# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- rve PF00665.21 KZN83379.1 - 1.3e-14 54.3 0.0 2.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KZN83379.1 - 2.2e-05 23.9 0.0 5.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 KZN83379.1 - 0.00019 21.0 0.2 0.00059 19.4 0.1 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN83380.1 - 1.2e-05 24.9 0.5 2.2e-05 24.0 0.3 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type p450 PF00067.17 KZN83381.1 - 5.7e-38 130.6 0.0 7.7e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ring_hydroxyl_A PF00848.14 KZN83382.1 - 9.5e-38 129.9 1.7 1.9e-37 128.9 1.2 1.5 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KZN83382.1 - 8.8e-15 54.0 0.0 1.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 KZN83383.1 - 2.4e-10 39.7 4.7 5.7e-10 38.5 3.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE PF01188.16 KZN83384.1 - 3.4e-14 53.1 0.0 7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 KZN83384.1 - 1.4e-12 47.5 0.0 3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KZN83384.1 - 0.00013 21.9 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Epimerase PF01370.16 KZN83385.1 - 4.6e-14 52.4 0.4 2e-08 33.9 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN83385.1 - 5.6e-14 52.5 0.0 1.4e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN83385.1 - 9.7e-13 47.4 0.0 5.9e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN83385.1 - 3.4e-08 33.5 0.1 1.1e-07 31.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KZN83385.1 - 4.3e-08 32.6 0.1 8.3e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KZN83385.1 - 9.6e-08 31.2 0.1 0.007 15.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 KZN83385.1 - 0.00022 20.9 0.2 0.0055 16.3 0.1 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KZN83385.1 - 0.028 13.3 0.3 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 KZN83386.1 - 3e-104 349.1 15.2 3.4e-104 348.9 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83386.1 - 7.2e-24 84.1 12.6 7.2e-24 84.1 8.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN83386.1 - 0.0055 16.4 1.6 0.022 14.5 0.0 2.7 3 0 0 3 3 3 1 MFS_1 like family ATP-grasp_4 PF13535.1 KZN83387.1 - 2.3e-07 30.7 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KZN83387.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KZN83387.1 - 7.8e-06 25.4 0.0 2.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN83387.1 - 0.00017 20.4 0.0 0.0057 15.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KZN83387.1 - 0.00045 19.6 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KZN83387.1 - 0.0013 18.3 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CP_ATPgrasp_1 PF04174.8 KZN83387.1 - 0.0022 16.6 0.0 0.034 12.7 0.0 2.1 2 0 0 2 2 2 1 A circularly permuted ATPgrasp Pyr_redox PF00070.22 KZN83388.1 - 2e-14 53.7 0.0 2.3e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN83388.1 - 1e-12 48.3 0.0 0.0014 18.5 0.0 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN83388.1 - 2e-09 36.8 0.0 0.015 14.1 0.0 3.5 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN83388.1 - 1.7e-07 31.5 0.4 0.0035 17.4 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN83388.1 - 3.8e-07 29.3 0.1 1.2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KZN83388.1 - 1.2e-06 28.6 0.0 7.2e-05 22.9 0.0 2.8 3 1 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KZN83388.1 - 4.4e-06 26.6 0.0 0.0086 16.0 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KZN83388.1 - 0.00013 21.9 0.8 0.051 13.5 0.0 3.7 5 0 0 5 5 5 1 TrkA-N domain NAD_binding_9 PF13454.1 KZN83388.1 - 0.00014 21.6 0.5 3.1 7.5 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KZN83388.1 - 0.0005 18.8 0.0 0.19 10.2 0.0 2.4 2 1 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 KZN83388.1 - 0.008 15.1 0.0 0.059 12.2 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein ApbA PF02558.11 KZN83388.1 - 0.032 13.6 0.0 0.25 10.7 0.0 2.5 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SGL PF08450.7 KZN83389.1 - 4.1e-09 36.1 0.1 0.0028 17.0 0.0 3.1 2 1 1 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region B_lectin PF01453.19 KZN83389.1 - 0.0079 16.0 0.1 3.7 7.4 0.0 2.7 3 0 0 3 3 3 2 D-mannose binding lectin Oxidored_FMN PF00724.15 KZN83390.1 - 4.6e-47 160.6 0.0 6.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UPF0160 PF03690.8 KZN83390.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Polysacc_deac_2 PF04748.8 KZN83390.1 - 0.048 12.6 0.0 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Fungal_trans PF04082.13 KZN83391.1 - 3.7e-16 58.7 0.0 5e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.12 KZN83392.1 - 1.6e-62 210.1 0.0 2.3e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.13 KZN83393.1 - 4.2e-11 42.2 2.3 2e-10 40.0 1.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.3 KZN83394.1 - 2.2e-11 43.1 1.9 3.8e-11 42.4 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2406 PF10295.4 KZN83396.1 - 1.7e-20 73.3 1.7 2.5e-20 72.7 1.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein (DUF2406) Glyco_hydro_72 PF03198.9 KZN83397.1 - 3.1e-120 400.9 5.5 3.6e-119 397.4 3.8 2.0 1 1 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KZN83397.1 - 2.1e-25 88.9 8.0 9.9e-25 86.8 5.5 2.2 1 0 0 1 1 1 1 X8 domain TA0956 PF11513.3 KZN83397.1 - 0.041 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Abhydrolase_6 PF12697.2 KZN83398.1 - 2.6e-17 63.4 0.2 4e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN83398.1 - 6.5e-08 32.4 0.4 7.4e-07 29.0 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AP_endonuc_2 PF01261.19 KZN83398.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Abhydrolase_1 PF00561.15 KZN83398.1 - 0.12 11.9 0.1 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold CorA PF01544.13 KZN83399.1 - 1.7e-11 43.6 2.8 3.5e-11 42.6 1.9 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PSD3 PF07626.6 KZN83399.1 - 0.057 13.4 0.7 0.16 11.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) DUF2677 PF10838.3 KZN83399.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) FAD_binding_4 PF01565.18 KZN83400.1 - 2e-27 95.3 0.2 4.4e-27 94.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain CopD PF05425.8 KZN83401.1 - 5.4 7.2 11.1 0.26 11.5 1.3 2.9 1 1 2 3 3 3 0 Copper resistance protein D Cupin_2 PF07883.6 KZN83402.1 - 1.1e-05 24.8 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 KZN83403.1 - 3.3e-13 49.8 0.2 4.6e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83403.1 - 4.6e-08 32.9 0.3 6.6e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN83403.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KZN83403.1 - 0.0027 16.6 0.1 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein TPP_enzyme_C PF02775.16 KZN83403.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Shikimate_DH PF01488.15 KZN83403.1 - 0.13 12.3 0.1 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MBOAT_2 PF13813.1 KZN83404.1 - 8.3e-20 70.6 1.6 9.1e-20 70.5 0.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.17 KZN83405.1 - 1.4e-55 188.6 0.0 2e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KZN83406.1 - 3.2e-86 288.9 1.9 6.4e-86 287.9 0.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN83406.1 - 3.7e-79 266.3 1.7 7.9e-79 265.2 1.2 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KZN83406.1 - 2.8e-59 199.8 0.8 8.1e-58 195.0 0.0 3.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KZN83406.1 - 2.9e-54 183.4 0.6 1.2e-52 178.2 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN83406.1 - 3.2e-40 136.6 1.8 2.4e-39 133.8 0.5 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KZN83406.1 - 4.1e-16 59.0 3.0 4.1e-16 59.0 2.1 2.1 3 0 0 3 3 3 1 Polyketide synthase dehydratase PP-binding PF00550.20 KZN83406.1 - 2.4e-09 37.2 0.0 8.4e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN83406.1 - 6.3e-06 25.3 0.0 1.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Strabismus PF06638.6 KZN83406.1 - 0.041 12.1 0.1 0.064 11.5 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein UbiA PF01040.13 KZN83407.1 - 2.5e-33 115.4 18.9 3.1e-33 115.0 13.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Amidohydro_2 PF04909.9 KZN83408.1 - 3.2e-25 89.2 0.3 6.6e-25 88.1 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase p450 PF00067.17 KZN83409.1 - 1.4e-80 271.0 0.0 1.9e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S-methyl_trans PF02574.11 KZN83410.1 - 9.8e-22 77.6 0.0 1.2e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ala_racemase_N PF01168.15 KZN83410.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Pkinase PF00069.20 KZN83411.1 - 1.9e-14 53.4 0.0 3e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83411.1 - 1.6e-12 47.0 0.0 2e-12 46.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN83411.1 - 0.0018 18.0 0.6 0.0027 17.4 0.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN83411.1 - 0.002 17.2 0.1 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_N PF08240.7 KZN83412.1 - 2.3e-22 78.8 7.2 3.7e-22 78.1 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN83412.1 - 5.8e-18 64.6 0.0 9e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN83412.1 - 0.00039 19.6 0.1 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KZN83412.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ferritin_2 PF13668.1 KZN83413.1 - 7.1e-31 106.9 7.0 3.9e-30 104.5 3.7 2.4 2 1 0 2 2 2 1 Ferritin-like domain DUF455 PF04305.9 KZN83413.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Rubrerythrin PF02915.12 KZN83413.1 - 0.24 11.7 0.9 0.74 10.1 0.5 1.8 2 1 0 2 2 2 0 Rubrerythrin PAAR_motif PF05488.8 KZN83414.1 - 1.1 9.3 10.9 0.33 10.9 0.4 3.0 2 1 0 2 2 2 0 PAAR motif MFS_1 PF07690.11 KZN83415.1 - 3.1e-32 111.6 22.5 3.1e-32 111.6 15.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ThylakoidFormat PF11264.3 KZN83415.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Thylakoid formation protein Sulfatase PF00884.18 KZN83416.1 - 6.1e-65 219.4 1.4 7.9e-65 219.0 0.9 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN83416.1 - 0.00022 20.6 1.3 0.051 12.8 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KZN83416.1 - 0.15 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UBN2_3 PF14244.1 KZN83417.1 - 4.7e-05 22.9 0.4 0.00042 19.9 0.3 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_transf_36 PF06165.6 KZN83417.1 - 0.071 12.9 0.1 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 MFS_1 PF07690.11 KZN83423.1 - 1.1e-45 155.8 44.3 2.3e-45 154.8 30.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83423.1 - 2e-14 53.0 8.1 2e-14 53.0 5.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KZN83423.1 - 8.4e-12 44.0 10.8 8.4e-12 44.0 7.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_15 PF00723.16 KZN83424.1 - 7.3e-106 354.4 0.1 8.8e-106 354.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KZN83424.1 - 2e-32 110.6 1.5 5.2e-32 109.3 1.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 KZN83425.1 - 6.5e-74 249.1 1.9 9.5e-74 248.6 1.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 KZN83425.1 - 2.4e-32 110.4 0.5 5.3e-32 109.2 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 KZN83425.1 - 2.9e-31 107.4 1.9 3.4e-31 107.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 KZN83425.1 - 0.00023 20.1 0.2 0.00031 19.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 hDGE_amylase PF14701.1 KZN83425.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF187 PF02638.10 KZN83425.1 - 0.044 12.6 0.2 0.069 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 COesterase PF00135.23 KZN83426.1 - 2.2e-96 323.7 0.0 3e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN83426.1 - 3.4e-05 23.5 0.6 0.0002 21.0 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN83426.1 - 0.012 14.8 0.2 0.39 9.8 0.2 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family PTR2 PF00854.16 KZN83427.1 - 1.1e-39 136.3 10.2 1.6e-39 135.8 7.1 1.2 1 0 0 1 1 1 1 POT family Lipase_3 PF01764.20 KZN83430.1 - 8.3e-30 103.2 0.0 1.2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KZN83430.1 - 0.0004 20.1 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 KZN83430.1 - 0.055 13.2 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KZN83430.1 - 0.064 12.5 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pyr_redox_3 PF13738.1 KZN83431.1 - 2.3e-29 102.9 0.0 7.2e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN83431.1 - 1.1e-17 63.4 0.0 1.1e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN83431.1 - 3e-12 46.3 0.0 2e-09 37.3 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN83431.1 - 1.8e-09 36.9 0.1 3.5e-07 29.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN83431.1 - 2.3e-07 30.8 0.2 0.019 14.8 0.0 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN83431.1 - 5.8e-07 28.7 0.1 8.3e-05 21.6 0.0 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN83431.1 - 1.8e-06 27.2 0.0 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KZN83431.1 - 7.5e-05 23.0 0.0 0.017 15.5 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN83431.1 - 0.0001 22.1 0.3 0.52 10.0 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KZN83431.1 - 0.00017 20.6 0.0 0.0096 14.8 0.0 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KZN83431.1 - 0.0025 16.9 0.1 0.47 9.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KZN83431.1 - 0.0037 16.4 0.0 2.1 7.3 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 KZN83431.1 - 0.012 15.7 0.0 0.31 11.1 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KZN83431.1 - 0.013 14.3 0.0 0.07 11.9 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.10 KZN83431.1 - 0.02 13.1 0.0 0.46 8.5 0.0 2.5 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 KZN83431.1 - 0.028 13.2 0.9 0.73 8.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KZN83431.1 - 0.029 14.6 0.0 0.11 12.7 0.0 2.0 3 0 0 3 3 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KZN83431.1 - 0.15 11.0 0.1 16 4.4 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 KZN83431.1 - 0.19 10.3 0.1 6.1 5.3 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 KZN83431.1 - 0.25 9.7 0.1 1.5 7.1 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein Abhydrolase_3 PF07859.8 KZN83432.1 - 7.5e-22 77.9 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN83432.1 - 8.3e-13 47.7 0.0 1.6e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KZN83432.1 - 1.4e-06 28.0 0.1 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN83432.1 - 0.063 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.20 KZN83433.1 - 5.2e-24 85.0 0.1 1.2e-23 83.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN83433.1 - 6.8e-09 35.8 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN83433.1 - 1.7e-06 27.7 2.7 1.2e-05 25.1 0.6 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN83433.1 - 0.001 18.5 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN83433.1 - 0.0085 16.1 0.1 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding ThiF PF00899.16 KZN83433.1 - 0.086 12.6 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 ThiF family p450 PF00067.17 KZN83434.1 - 1.4e-75 254.6 0.0 1.8e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2841 PF11001.3 KZN83434.1 - 0.044 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) MFS_1 PF07690.11 KZN83435.1 - 9.4e-32 110.0 25.4 9.4e-32 110.0 17.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83435.1 - 2.3e-10 39.6 6.6 2.3e-10 39.6 4.6 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KZN83435.1 - 1.7e-07 29.8 3.4 1.7e-07 29.8 2.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_28 PF00295.12 KZN83436.1 - 7e-51 173.1 3.0 1e-50 172.5 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4528 PF15031.1 KZN83436.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) YabP PF07873.6 KZN83436.1 - 0.089 12.3 0.5 0.35 10.4 0.1 2.2 3 0 0 3 3 3 0 YabP family MAPEG PF01124.13 KZN83437.1 - 5.1e-14 51.9 1.4 7e-14 51.5 0.9 1.2 1 0 0 1 1 1 1 MAPEG family Pyridoxal_deC PF00282.14 KZN83438.1 - 1.9e-71 240.5 0.0 2.3e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Rubis-subs-bind PF09273.6 KZN83438.1 - 0.089 12.7 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Fungal_trans PF04082.13 KZN83439.1 - 3.7e-21 75.1 0.2 7.6e-21 74.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83439.1 - 2.8e-07 30.3 9.0 6.8e-07 29.0 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KZN83440.1 - 2.2e-74 249.1 50.1 8.1e-40 136.2 18.0 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN83440.1 - 2.5e-37 128.2 0.0 2.7e-17 63.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN83440.1 - 6.7e-26 89.9 12.8 1.7e-25 88.6 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 KZN83440.1 - 1.9e-09 37.2 0.1 0.00045 19.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KZN83440.1 - 7.4e-07 29.3 2.7 1.1e-05 25.5 0.3 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 KZN83440.1 - 3e-06 27.3 0.1 0.0033 17.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KZN83440.1 - 1.4e-05 24.5 0.5 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KZN83440.1 - 3e-05 23.2 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KZN83440.1 - 0.00013 21.0 45.4 0.013 14.5 16.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein MMR_HSR1 PF01926.18 KZN83440.1 - 0.00022 21.1 0.0 0.041 13.8 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KZN83440.1 - 0.00064 19.2 0.1 0.2 11.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KZN83440.1 - 0.0012 18.9 0.3 0.25 11.5 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KZN83440.1 - 0.002 18.0 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KZN83440.1 - 0.0084 16.6 0.0 0.22 12.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KZN83440.1 - 0.018 14.5 0.1 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KZN83440.1 - 0.032 14.5 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KZN83440.1 - 0.032 14.5 0.1 0.074 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KZN83440.1 - 0.033 13.2 0.0 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KZN83440.1 - 0.04 13.5 0.4 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KZN83440.1 - 0.04 13.5 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KZN83440.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN83440.1 - 0.085 13.6 0.0 0.63 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KZN83440.1 - 0.086 12.0 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ArgK PF03308.11 KZN83440.1 - 0.12 11.1 0.1 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 KZN83440.1 - 0.13 11.8 0.4 9.1 5.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KZN83440.1 - 0.17 11.3 0.4 0.82 9.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KZN83440.1 - 0.22 11.3 0.2 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 KZN83440.1 - 0.29 10.1 0.5 10 5.1 0.4 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.4 KZN83440.1 - 0.44 9.0 0.0 0.73 8.3 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF1115 PF06544.7 KZN83441.1 - 0.00034 20.2 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Glyco_transf_8 PF01501.15 KZN83442.1 - 0.0011 18.3 0.1 0.0011 18.3 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KZN83442.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Methyltransf_2 PF00891.13 KZN83444.1 - 1e-17 64.1 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KZN83444.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KZN83444.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain MFS_1 PF07690.11 KZN83445.1 - 1.3e-23 83.3 46.7 1.3e-23 83.3 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAN_1 PF00024.21 KZN83446.1 - 5.3e-05 22.8 0.2 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 KZN83446.1 - 6.3e-05 22.3 2.0 0.0017 17.6 0.2 3.1 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.1 KZN83446.1 - 0.0057 16.3 0.4 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 PAN domain DUF2235 PF09994.4 KZN83447.1 - 1.5e-80 270.5 0.0 1.8e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UPF0542 PF15086.1 KZN83447.1 - 0.043 13.5 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Pkinase PF00069.20 KZN83449.1 - 4.3e-46 157.1 0.0 6e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_12 PF13424.1 KZN83449.1 - 3.1e-30 103.9 21.7 1.2e-10 41.1 1.0 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 KZN83449.1 - 7.2e-25 87.5 0.0 1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.1 KZN83449.1 - 1.4e-19 69.3 14.1 6.8e-07 29.0 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN83449.1 - 2.8e-11 42.4 9.8 0.026 14.4 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN83449.1 - 2.8e-10 39.6 2.3 0.00068 19.2 0.1 3.5 2 1 0 3 3 3 3 TPR repeat Apc3 PF12895.2 KZN83449.1 - 1.9e-08 34.3 7.3 3.8e-07 30.1 1.7 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KZN83449.1 - 9.8e-08 31.2 1.4 0.19 11.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 KZN83449.1 - 1.3e-07 31.2 2.1 0.95 9.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN83449.1 - 2.2e-07 31.3 6.8 0.0025 18.4 0.5 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN83449.1 - 0.00022 21.5 1.8 4.6 8.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Kdo PF06293.9 KZN83449.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_6 PF13174.1 KZN83449.1 - 0.0084 16.5 10.8 0.12 12.9 0.3 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN83449.1 - 0.064 13.6 0.1 1.3 9.4 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat Pox_ser-thr_kin PF05445.6 KZN83449.1 - 0.2 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 KZN83450.1 - 8.1e-18 64.2 59.0 2.6e-10 39.5 19.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.10 KZN83450.1 - 3.3e-07 29.3 6.0 3.3e-07 29.3 4.2 2.5 4 0 0 4 4 4 1 PUCC protein Fungal_trans PF04082.13 KZN83451.1 - 2e-20 72.7 0.0 3.8e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83451.1 - 3.1e-07 30.1 14.2 5e-07 29.5 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF500 PF04366.7 KZN83452.1 - 2.1e-44 149.9 0.1 3.2e-44 149.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) DHquinase_I PF01487.10 KZN83454.1 - 9.7e-48 162.7 0.0 1.4e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KZN83454.1 - 1.9e-19 70.0 0.5 6.4e-19 68.3 0.0 2.2 3 0 0 3 3 3 1 Shikimate kinase Shikimate_DH PF01488.15 KZN83454.1 - 4e-14 52.8 0.0 9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 KZN83454.1 - 2.1e-13 50.0 0.0 5.2e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 KZN83454.1 - 0.0068 16.8 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KZN83454.1 - 0.058 13.2 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 ThiF family BAF1_ABF1 PF04684.8 KZN83455.1 - 0.039 12.7 2.3 0.058 12.2 1.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 KZN83455.1 - 7 4.7 6.9 8 4.5 4.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prenyltransf PF01255.14 KZN83456.1 - 0.0025 16.9 0.0 0.0066 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 KZN83457.1 - 1.3e-230 767.4 0.0 1.5e-230 767.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 FlgN PF05130.7 KZN83457.1 - 0.02 15.1 6.0 3.5 7.8 0.5 3.8 4 0 0 4 4 4 0 FlgN protein Tropomyosin PF00261.15 KZN83457.1 - 0.13 11.3 0.1 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Tropomyosin Apolipoprotein PF01442.13 KZN83457.1 - 0.14 11.6 6.4 3.5 7.0 2.0 3.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KZN83457.1 - 0.35 10.6 5.8 1.6 8.5 0.4 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_tranf_2_3 PF13641.1 KZN83458.1 - 7.4e-20 71.7 0.0 1.2e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KZN83458.1 - 3.4e-10 39.9 0.5 3.4e-10 39.9 0.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KZN83458.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KZN83458.1 - 0.0028 16.9 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 BNR PF02012.15 KZN83460.1 - 1.2e-07 30.4 23.1 5 7.3 0.2 10.2 10 0 0 10 10 10 6 BNR/Asp-box repeat DUF2167 PF09935.4 KZN83460.1 - 0.0037 16.1 0.4 0.011 14.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2167) dCMP_cyt_deam_1 PF00383.17 KZN83461.1 - 2.3e-16 59.3 0.3 2.7e-16 59.0 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KZN83461.1 - 3.6e-09 36.6 0.8 8.4e-08 32.2 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KZN83461.1 - 9.1e-06 25.1 0.6 0.07 12.5 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Peptidase_C12 PF01088.16 KZN83462.1 - 3.6e-38 130.9 0.0 6.4e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NmrA PF05368.8 KZN83462.1 - 5.6e-33 114.1 0.0 8.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN83462.1 - 1.5e-08 34.8 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding CmcI PF04989.7 KZN83462.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Fungal_trans PF04082.13 KZN83463.1 - 4.5e-19 68.3 0.0 8.1e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83463.1 - 0.014 15.3 4.9 0.026 14.4 3.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 KZN83464.1 - 2.1e-66 219.6 0.4 2.4e-22 78.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.9 KZN83465.1 - 5.4e-38 129.5 23.5 6.1e-38 129.3 16.3 1.0 1 0 0 1 1 1 1 Cgr1 family 2OG-FeII_Oxy_4 PF13661.1 KZN83465.1 - 0.046 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PRP1_N PF06424.7 KZN83465.1 - 0.18 12.1 8.3 0.22 11.8 5.7 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal N2227 PF07942.7 KZN83465.1 - 0.43 9.4 1.9 0.49 9.2 1.3 1.2 1 0 0 1 1 1 0 N2227-like protein Golgin_A5 PF09787.4 KZN83465.1 - 1.2 7.5 15.0 1.4 7.3 10.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 3HCDH_N PF02737.13 KZN83465.1 - 1.2 8.7 3.5 1.4 8.5 2.5 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDHD PF02862.12 KZN83465.1 - 1.5 8.6 5.1 1.7 8.4 3.5 1.0 1 0 0 1 1 1 0 DDHD domain DUF2058 PF09831.4 KZN83465.1 - 2.3 8.0 14.1 2.8 7.7 9.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Adeno_VII PF03228.9 KZN83465.1 - 4.9 7.7 7.5 6.1 7.4 5.2 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII GAS PF13851.1 KZN83466.1 - 0.00022 20.5 2.3 0.00039 19.6 1.6 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KZN83466.1 - 0.0019 16.7 0.8 0.0026 16.2 0.5 1.1 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 KZN83466.1 - 0.013 15.3 1.5 0.11 12.3 1.0 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KZN83466.1 - 0.013 14.1 0.9 0.02 13.5 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein LXG PF04740.7 KZN83466.1 - 0.019 14.7 1.0 0.03 14.0 0.7 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily MitMem_reg PF13012.1 KZN83466.1 - 0.033 14.2 0.5 0.088 12.9 0.3 1.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function AAA_27 PF13514.1 KZN83466.1 - 0.053 11.2 5.4 0.06 11.0 2.9 1.5 1 1 0 1 1 1 0 AAA domain MtrG PF04210.8 KZN83466.1 - 0.074 12.7 0.2 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Snapin_Pallidin PF14712.1 KZN83466.1 - 0.081 13.2 1.1 0.21 11.9 0.7 1.7 1 0 0 1 1 1 0 Snapin/Pallidin EMP24_GP25L PF01105.19 KZN83466.1 - 0.16 11.6 0.5 0.27 10.9 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MtrB PF05440.7 KZN83466.1 - 0.19 11.7 0.0 2.7 8.0 0.0 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF3552 PF12072.3 KZN83466.1 - 0.34 10.1 4.2 0.73 9.0 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF948 PF06103.6 KZN83466.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.8 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF948) DUF607 PF04678.8 KZN83466.1 - 2.2 8.1 5.9 0.26 11.2 0.4 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF607 BicD PF09730.4 KZN83466.1 - 2.2 6.5 13.7 0.013 13.9 2.9 1.8 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D SUI1 PF01253.17 KZN83467.1 - 5.9e-20 70.8 0.5 1e-19 70.0 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 KZN83467.1 - 0.0083 16.0 0.1 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF1752 PF08550.5 KZN83468.1 - 4.1e-11 42.2 3.8 7.6e-11 41.3 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.8 KZN83469.1 - 4.9e-46 156.3 0.0 1e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KZN83469.1 - 0.00012 21.8 0.2 0.0013 18.4 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Rad17 PF03215.10 KZN83470.1 - 1.4e-56 192.2 0.0 2.1e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KZN83470.1 - 7.4e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KZN83470.1 - 0.0006 20.6 0.0 0.0016 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN83470.1 - 0.00065 19.9 0.0 0.0017 18.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KZN83470.1 - 0.00077 19.1 0.0 0.0024 17.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN83470.1 - 0.018 15.1 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KZN83470.1 - 0.024 14.2 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN83470.1 - 0.028 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KZN83470.1 - 0.051 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KZN83470.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KZN83470.1 - 0.18 11.4 0.2 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain UAA PF08449.6 KZN83471.1 - 1.9e-79 266.7 8.2 4.7e-79 265.4 5.7 1.5 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KZN83471.1 - 0.00012 21.2 0.3 0.00026 20.1 0.2 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KZN83471.1 - 0.00017 21.2 9.6 0.0013 18.3 6.7 2.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Mannosyl_trans3 PF11051.3 KZN83471.1 - 0.091 12.0 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Mannosyltransferase putative EamA PF00892.15 KZN83471.1 - 0.25 11.4 26.3 0.095 12.7 4.0 3.6 3 2 1 4 4 4 0 EamA-like transporter family EmrE PF13536.1 KZN83471.1 - 0.98 9.6 30.1 0.051 13.7 1.6 4.1 3 2 2 5 5 5 0 Multidrug resistance efflux transporter Dynamin_M PF01031.15 KZN83472.1 - 7.4e-114 379.4 0.0 1.4e-113 378.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KZN83472.1 - 8.5e-54 181.8 0.0 1.6e-53 180.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KZN83472.1 - 7e-31 105.9 0.6 7e-31 105.9 0.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KZN83472.1 - 0.00073 19.4 0.2 0.0047 16.8 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN83472.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 KZN83472.1 - 0.025 13.8 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SH3_9 PF14604.1 KZN83473.1 - 1.3e-28 98.2 5.6 2.9e-14 52.3 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KZN83473.1 - 1.5e-24 85.1 6.2 1.4e-12 46.7 0.4 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KZN83473.1 - 1.5e-15 56.4 0.5 6.4e-07 28.7 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KZN83473.1 - 1.9e-10 40.6 0.0 3.4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein A_deaminase PF00962.17 KZN83474.1 - 1.6e-114 382.3 0.0 2.2e-114 381.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MAP65_ASE1 PF03999.7 KZN83475.1 - 4.2 5.8 8.3 7.9 4.9 5.8 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3752 PF12572.3 KZN83476.1 - 2.5e-38 131.6 13.7 2.8e-38 131.4 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) BNIP3 PF06553.7 KZN83476.1 - 0.1 11.9 7.5 0.023 14.0 2.8 1.5 1 1 1 2 2 2 0 BNIP3 ORC6 PF05460.8 KZN83476.1 - 1.6 7.7 8.5 1.9 7.4 5.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3408 PF11888.3 KZN83476.1 - 3.9 7.3 6.3 5.9 6.8 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Metallophos PF00149.23 KZN83477.1 - 8.3e-09 35.1 0.9 8.1e-07 28.6 0.7 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN83477.1 - 2.6e-06 27.3 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box PF00646.28 KZN83478.1 - 1.1e-05 24.9 0.0 2.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KZN83478.1 - 6.4e-05 22.6 0.2 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like ALAD PF00490.16 KZN83479.1 - 3.4e-119 397.5 0.0 4.1e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac PF12464.3 KZN83480.1 - 7.3e-13 48.3 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KZN83480.1 - 9.4e-10 38.2 8.4 1.8e-09 37.3 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 KZN83480.1 - 1.4e-09 37.0 9.4 3e-05 23.3 0.3 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KZN83480.1 - 1.1e-05 24.9 8.3 0.00016 21.1 0.9 3.6 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase CRA PF06589.6 KZN83480.1 - 0.75 9.0 2.2 2 7.6 1.5 1.7 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) CRM1_C PF08767.6 KZN83481.1 - 4.2e-135 449.7 4.7 4.2e-135 449.7 3.2 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KZN83481.1 - 1.3e-43 148.4 10.5 3.6e-43 147.0 3.2 4.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KZN83481.1 - 8.7e-12 44.7 0.1 3.8e-11 42.7 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KZN83481.1 - 0.011 15.6 0.6 0.16 11.9 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) PPI_Ypi1 PF07491.6 KZN83482.1 - 1.4e-25 88.6 6.4 5.4e-25 86.7 4.4 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor RNA_polI_A34 PF08208.6 KZN83482.1 - 2.2 7.9 10.4 4.6 6.8 7.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 KZN83482.1 - 7.8 4.3 7.3 7.7 4.4 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Shugoshin_N PF07558.6 KZN83483.1 - 2.1e-16 59.3 5.1 2.1e-16 59.3 3.5 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KZN83483.1 - 8.7e-11 41.0 4.7 8.7e-11 41.0 3.3 2.9 4 0 0 4 4 4 1 Shugoshin C terminus bZIP_1 PF00170.16 KZN83483.1 - 0.037 13.9 2.3 0.064 13.2 0.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.3 KZN83483.1 - 1.4 8.7 6.0 0.92 9.3 2.0 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DASH_Dad2 PF08654.5 KZN83484.1 - 3.6e-32 110.4 0.2 4.5e-32 110.1 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Dapper PF15268.1 KZN83484.1 - 0.016 14.0 0.2 0.021 13.6 0.2 1.1 1 0 0 1 1 1 0 Dapper Seryl_tRNA_N PF02403.17 KZN83484.1 - 0.018 15.0 0.2 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain p450 PF00067.17 KZN83485.1 - 3.3e-71 240.2 0.0 3.7e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 KZN83486.1 - 1.4e-50 172.1 0.0 1.9e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN83486.1 - 7e-09 35.0 1.1 2e-08 33.5 0.8 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KZN83486.1 - 1.4e-05 24.3 0.2 0.00016 20.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN83486.1 - 0.00013 21.9 0.1 0.00075 19.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN83486.1 - 0.001 19.0 0.1 0.0039 17.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KZN83486.1 - 0.0022 17.6 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KZN83486.1 - 0.0064 15.6 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KZN83486.1 - 0.012 14.5 0.0 0.078 11.8 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KZN83486.1 - 0.019 13.4 0.2 0.033 12.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KZN83486.1 - 0.027 13.5 0.1 0.051 12.6 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KZN83486.1 - 0.039 14.3 0.3 0.13 12.6 0.2 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN83486.1 - 0.073 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN83486.1 - 0.1 11.4 0.1 0.61 8.8 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.13 KZN83486.1 - 0.1 10.8 0.1 0.31 9.3 0.0 1.7 2 0 0 2 2 2 0 GDP dissociation inhibitor DUF814 PF05670.8 KZN83488.1 - 4.3e-16 58.5 0.6 6.6e-15 54.7 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF814) TBCC PF07986.7 KZN83488.1 - 0.0025 17.2 0.2 0.05 13.0 0.0 2.5 2 1 0 2 2 2 1 Tubulin binding cofactor C Y_phosphatase3 PF13350.1 KZN83488.1 - 0.63 10.2 4.2 0.98 9.6 2.9 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Paramyxo_ncap PF00973.14 KZN83488.1 - 1.6 7.3 6.7 2 6.9 4.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pox_P35 PF03213.9 KZN83488.1 - 4.1 6.3 8.3 6.7 5.6 4.1 1.9 1 1 1 2 2 2 0 Poxvirus P35 protein GRAB PF10375.4 KZN83489.1 - 7.2e-09 34.9 0.2 1.6e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 KZN83489.1 - 3.2e-05 23.2 11.6 0.0013 18.0 3.4 2.4 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 KZN83489.1 - 0.0024 17.3 6.3 0.0024 17.3 4.4 4.0 1 1 3 4 4 4 1 Phage minor structural protein GP20 Filament PF00038.16 KZN83489.1 - 0.011 15.2 51.8 0.012 15.0 13.1 3.0 1 1 2 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.7 KZN83489.1 - 0.064 13.0 20.9 0.41 10.4 3.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 KZN83489.1 - 0.22 10.4 38.8 0.14 11.1 12.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ApoO PF09769.4 KZN83489.1 - 0.32 10.6 13.3 1.3 8.7 1.6 3.9 1 1 3 4 4 4 0 Apolipoprotein O AAA_13 PF13166.1 KZN83489.1 - 0.98 7.8 42.7 0.41 9.0 16.1 2.1 1 1 1 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 KZN83489.1 - 3.7 7.3 62.3 1.5 8.5 9.2 4.7 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 KZN83489.1 - 5.2 4.4 30.0 0.36 8.3 12.8 2.0 1 1 1 2 2 2 0 Prominin Laminin_II PF06009.7 KZN83489.1 - 6.8 6.4 35.6 0.16 11.7 3.1 4.3 1 1 3 4 4 4 0 Laminin Domain II DUF3584 PF12128.3 KZN83489.1 - 7.6 3.7 53.8 16 2.6 37.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.1 KZN83489.1 - 8.3 5.7 59.9 0.08 12.3 11.6 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Guanylate_kin PF00625.16 KZN83490.1 - 5.1e-65 218.3 0.0 6.2e-65 218.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KZN83490.1 - 1.2e-06 28.4 0.1 4.8e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN83490.1 - 3.1e-06 28.0 0.2 3e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN83490.1 - 3.5e-06 27.3 0.1 2.4e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN83490.1 - 3.6e-06 27.1 0.3 1.6e-05 24.9 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN83490.1 - 2.6e-05 24.3 0.0 9.2e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KZN83490.1 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 KZN83490.1 - 0.00027 20.9 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KZN83490.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KZN83490.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 DUF2075 PF09848.4 KZN83490.1 - 0.0012 17.9 0.0 0.028 13.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KZN83490.1 - 0.0021 17.0 0.0 0.004 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KZN83490.1 - 0.0034 17.1 0.0 0.0084 15.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 KZN83490.1 - 0.0046 17.4 0.0 0.0072 16.8 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 KZN83490.1 - 0.0048 17.0 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 KZN83490.1 - 0.0052 16.7 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KZN83490.1 - 0.0056 16.4 0.1 0.0078 15.9 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 KZN83490.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 KZN83490.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 KZN83490.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Rad17 PF03215.10 KZN83490.1 - 0.016 13.8 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KZN83490.1 - 0.019 14.6 0.1 0.031 14.0 0.1 1.6 1 1 0 1 1 1 0 NTPase AAA PF00004.24 KZN83490.1 - 0.022 14.9 0.1 0.04 14.1 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1895 PF08988.5 KZN83490.1 - 0.023 14.7 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) AAA_30 PF13604.1 KZN83490.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KZN83490.1 - 0.038 13.7 0.1 0.26 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KZN83490.1 - 0.042 13.4 0.1 0.065 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KZN83490.1 - 0.042 13.2 0.5 0.29 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KZN83490.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 KZN83490.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KZN83490.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KZN83490.1 - 0.16 12.3 3.9 0.53 10.5 2.7 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KZN83491.1 - 4.5e-113 376.9 0.7 5.3e-113 376.7 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KZN83491.1 - 1.6e-07 31.2 0.0 3.2e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KZN83491.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KZN83491.1 - 0.00011 21.4 0.0 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KZN83491.1 - 0.00021 20.7 0.5 0.0096 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KZN83491.1 - 0.00023 21.0 0.5 0.57 9.9 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KZN83491.1 - 0.0019 17.6 0.1 0.0019 17.6 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KZN83491.1 - 0.0031 16.6 0.2 0.024 13.7 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 KZN83491.1 - 0.0041 17.4 0.0 0.006 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KZN83491.1 - 0.008 16.4 0.6 0.014 15.7 0.3 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 KZN83491.1 - 0.019 13.8 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KZN83491.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN83491.1 - 0.024 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 KZN83491.1 - 0.038 12.8 0.1 0.11 11.3 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 KZN83491.1 - 0.055 13.9 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KZN83491.1 - 0.063 13.2 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KZN83491.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.18 KZN83492.1 - 7.3e-14 51.6 4.7 9.8e-14 51.2 3.3 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 KZN83492.1 - 0.02 14.6 0.4 0.037 13.8 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KZN83492.1 - 2.7 7.3 7.6 1.5 8.1 0.3 2.1 1 1 1 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 KZN83493.1 - 2.6e-31 106.3 14.3 3.9e-11 42.3 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KZN83493.1 - 7.3e-05 22.5 0.0 0.0045 16.7 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 KZN83493.1 - 0.0014 17.7 0.0 0.0092 15.0 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 KZN83493.1 - 0.0052 15.1 0.1 1.4 7.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 KZN83493.1 - 0.0063 16.1 0.2 14 5.5 0.0 3.9 3 1 1 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KZN83493.1 - 0.013 13.6 0.7 0.024 12.7 0.1 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KZN83493.1 - 0.079 11.6 0.1 0.8 8.3 0.1 2.4 1 1 0 1 1 1 0 Nup133 N terminal like Apc4_WD40 PF12894.2 KZN83493.1 - 0.11 11.9 0.0 52 3.4 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pyridox_oxidase PF01243.15 KZN83493.1 - 0.13 12.2 0.0 24 5.0 0.0 2.8 1 1 2 3 3 3 0 Pyridoxamine 5'-phosphate oxidase Spindle_Spc25 PF08234.7 KZN83494.1 - 8.6e-22 76.9 0.2 3.6e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 KZN83494.1 - 0.0018 17.7 11.5 0.0027 17.2 8.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Rrn6 PF10214.4 KZN83494.1 - 0.023 12.8 1.2 0.028 12.5 0.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TarH PF02203.10 KZN83494.1 - 0.63 9.8 8.7 1.1 9.0 5.3 1.9 2 0 0 2 2 2 0 Tar ligand binding domain homologue CM_2 PF01817.16 KZN83494.1 - 3.3 7.8 11.1 4.5 7.4 2.0 2.7 2 1 1 3 3 3 0 Chorismate mutase type II Rrn6 PF10214.4 KZN83495.1 - 1.4e-156 522.7 0.0 1.7e-156 522.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor HMA PF00403.21 KZN83496.1 - 4.7e-17 61.8 1.0 5.9e-17 61.5 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.9 KZN83496.1 - 0.015 15.0 0.1 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF2293 PF10056.4 KZN83497.1 - 2.7e-28 97.7 0.2 8.9e-28 96.0 0.1 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) RtcB PF01139.12 KZN83497.1 - 0.0067 15.4 2.0 0.014 14.4 1.4 1.4 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB zinc_ribbon_6 PF14599.1 KZN83498.1 - 7.2e-26 89.7 0.4 7.2e-26 89.7 0.3 3.7 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 KZN83498.1 - 2.3e-16 59.7 22.7 2.3e-16 59.7 15.7 4.2 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.1 KZN83498.1 - 1.1e-09 37.9 7.9 1.1e-09 37.9 5.5 4.3 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN83498.1 - 3.7e-07 29.7 7.8 3.7e-07 29.7 5.4 6.0 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN83498.1 - 8.5e-07 28.9 5.3 8.5e-07 28.9 3.7 5.6 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN83498.1 - 3.3e-06 26.7 2.7 3.3e-06 26.7 1.9 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.1 KZN83498.1 - 4e-05 23.2 8.4 4e-05 23.2 5.8 6.0 4 1 1 5 5 5 1 zinc-RING finger domain Nop14 PF04147.7 KZN83498.1 - 0.95 7.3 8.3 1.4 6.7 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 KZN83498.1 - 0.96 7.1 13.8 1.5 6.5 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 KZN83498.1 - 1.9 7.0 9.5 4.7 5.8 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tcp11 PF05794.8 KZN83499.1 - 1.5e-49 168.9 0.0 3.4e-49 167.7 0.0 1.6 2 0 0 2 2 2 1 T-complex protein 11 WD40 PF00400.27 KZN83500.1 - 1.1e-52 174.1 15.5 4.1e-11 42.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KZN83500.1 - 0.0033 16.8 0.0 6.5 6.3 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KZN83500.1 - 0.13 11.0 0.4 0.61 8.8 0.1 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Peptidase_S10 PF00450.17 KZN83501.1 - 7.6e-112 374.5 0.0 9.3e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MLANA PF14991.1 KZN83501.1 - 0.045 13.7 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Rifin_STEVOR PF02009.11 KZN83501.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF1811 PF08838.5 KZN83501.1 - 0.14 12.1 0.0 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF2530 PF10745.4 KZN83501.1 - 0.14 12.1 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) RNA_Me_trans PF04252.8 KZN83502.1 - 7.2e-47 159.3 0.0 8.8e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 KZN83503.1 - 8.2e-22 76.9 0.0 1.2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ICE2 PF08426.5 KZN83504.1 - 2.4e-141 471.1 11.5 2.8e-141 470.9 7.9 1.0 1 0 0 1 1 1 1 ICE2 UPF0160 PF03690.8 KZN83505.1 - 8e-119 396.7 0.0 9.1e-119 396.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Yae1_N PF09811.4 KZN83506.1 - 6.1e-07 28.8 2.7 9.2e-07 28.2 1.9 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal AAA_27 PF13514.1 KZN83506.1 - 0.016 12.9 0.1 0.018 12.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain tRNA-synt_1g PF09334.6 KZN83507.1 - 1.1e-137 458.8 0.0 1.4e-137 458.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KZN83507.1 - 1.4e-08 33.2 0.3 3e-05 22.2 0.0 3.6 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KZN83507.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Elongin_A PF06881.6 KZN83507.1 - 0.14 12.5 3.1 0.36 11.2 2.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DZR PF12773.2 KZN83507.1 - 0.66 9.8 5.4 2.2 8.1 3.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 KZN83508.1 - 9.8e-29 98.1 1.9 6.9e-07 28.9 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat FliO PF04347.8 KZN83508.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO DUF1374 PF07118.6 KZN83510.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1374) PXA PF02194.10 KZN83512.1 - 1.8e-51 174.3 0.5 1.8e-51 174.3 0.3 2.9 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KZN83512.1 - 2.8e-28 98.2 1.2 2.1e-27 95.4 0.0 2.9 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KZN83512.1 - 8.6e-22 77.0 0.6 1.8e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KZN83512.1 - 3.5e-11 43.2 0.0 1.3e-10 41.4 0.0 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain PEMT PF04191.8 KZN83513.1 - 1.2e-32 112.1 2.8 1.2e-32 112.1 1.9 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1223 PF06764.6 KZN83513.1 - 0.0084 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) YrhK PF14145.1 KZN83513.1 - 0.013 15.1 1.2 0.025 14.2 0.2 1.9 2 0 0 2 2 2 0 YrhK-like protein ATP1G1_PLM_MAT8 PF02038.11 KZN83513.1 - 0.9 8.6 2.8 2.3 7.3 1.9 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family RXT2_N PF08595.6 KZN83514.1 - 3.5e-40 137.2 2.2 5.5e-40 136.5 0.0 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal Gryzun PF07919.7 KZN83515.1 - 1.6e-147 492.2 0.0 1.9e-147 491.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KZN83515.1 - 4.2e-97 324.4 0.9 1.7e-86 289.7 1.7 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KZN83515.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 KZN83516.1 - 1.2e-20 74.3 0.3 2.4e-19 70.1 0.2 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN83516.1 - 3.1e-07 30.2 0.0 4.8e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN83516.1 - 3.4e-07 30.0 0.0 6.8e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KZN83516.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KZN83516.1 - 0.22 11.4 0.0 0.71 9.7 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Glutaredoxin PF00462.19 KZN83517.1 - 2.3e-12 46.6 0.0 8.7e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin FimP PF09766.4 KZN83517.1 - 0.00073 18.7 0.2 0.00073 18.7 0.1 1.5 2 0 0 2 2 2 1 Fms-interacting protein Neur_chan_memb PF02932.11 KZN83517.1 - 0.01 15.7 1.4 0.015 15.1 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Conotoxin PF02950.12 KZN83517.1 - 0.04 14.7 1.4 3.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Conotoxin GST_N_3 PF13417.1 KZN83517.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SHR3_chaperone PF08229.6 KZN83517.1 - 0.1 11.5 0.1 0.1 11.5 0.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 COX6C PF02937.10 KZN83517.1 - 0.13 12.1 0.3 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc TP53IP5 PF15331.1 KZN83517.1 - 1.1 9.1 11.0 1.1 9.0 4.8 2.0 1 1 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 AAA_11 PF13086.1 KZN83517.1 - 2.5 7.6 9.5 5.5 6.4 6.6 1.5 1 1 0 1 1 1 0 AAA domain Sec62 PF03839.11 KZN83517.1 - 4.3 6.6 7.1 8.1 5.7 3.6 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Ribosomal_L6 PF00347.18 KZN83518.1 - 3.8e-22 78.5 3.8 4.1e-10 40.0 0.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.3 KZN83519.1 - 1.7e-38 131.3 0.0 6.6e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KZN83519.1 - 5.1e-17 62.4 0.3 1.6e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.9 KZN83519.1 - 0.0099 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 NHR1 homology to TAF MVP_shoulder PF11978.3 KZN83519.1 - 0.14 12.0 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Shoulder domain ETC_C1_NDUFA4 PF04800.7 KZN83519.1 - 0.17 11.7 1.5 0.48 10.3 1.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region Pkinase PF00069.20 KZN83520.1 - 5.5e-27 94.5 0.0 1.9e-26 92.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83520.1 - 0.00073 18.6 0.1 0.012 14.6 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Aa_trans PF01490.13 KZN83521.1 - 4.3e-34 117.6 44.6 5.4e-28 97.5 20.3 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Spore_permease PF03845.8 KZN83521.1 - 2.9 6.4 32.2 0.062 11.9 15.2 2.8 2 1 0 2 2 2 0 Spore germination protein AA_permease_2 PF13520.1 KZN83522.1 - 1.3e-38 132.7 50.7 1.6e-38 132.4 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN83522.1 - 1.1e-24 86.6 44.7 1.4e-24 86.3 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease Tmemb_18A PF09771.4 KZN83522.1 - 2.6 8.0 5.5 2.4 8.1 2.1 2.2 1 1 1 2 2 2 0 Transmembrane protein 188 PhoD PF09423.5 KZN83523.1 - 6.8e-14 51.2 1.0 1.3e-08 33.8 0.3 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 KZN83528.1 - 9.5e-20 71.1 8.9 9.5e-20 71.1 6.1 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1449 PF07290.6 KZN83528.1 - 0.13 11.6 0.0 0.38 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) zf-C4H2 PF10146.4 KZN83529.1 - 0.17 11.9 0.7 0.2 11.6 0.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF904 PF06005.7 KZN83529.1 - 7.5 6.9 6.6 2.1 8.7 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Mob1_phocein PF03637.12 KZN83530.1 - 1.5e-30 106.1 1.3 2.3e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 Mob1/phocein family NdhO PF11910.3 KZN83530.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Leo1 PF04004.8 KZN83531.1 - 1.6e-29 102.7 1.3 1.7e-29 102.7 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein BOP1NT PF08145.7 KZN83532.1 - 1.7e-110 368.8 7.7 2.6e-110 368.2 5.3 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KZN83532.1 - 1e-25 88.6 9.1 1.5e-10 40.4 0.2 6.1 7 1 0 7 7 7 4 WD domain, G-beta repeat AAA PF00004.24 KZN83533.1 - 1.3e-89 297.1 0.0 8e-44 149.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN83533.1 - 2.5e-14 53.7 0.7 1.4e-06 28.4 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 KZN83533.1 - 1.5e-13 50.3 0.0 1.7e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KZN83533.1 - 3e-13 50.0 0.3 0.0012 18.9 0.0 5.6 3 2 1 4 4 3 2 AAA domain AAA_17 PF13207.1 KZN83533.1 - 7.1e-12 46.2 0.0 7.5e-07 29.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KZN83533.1 - 1.1e-10 41.4 0.2 0.0014 18.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN83533.1 - 1.6e-10 41.1 0.0 0.00018 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KZN83533.1 - 2.6e-10 40.2 0.0 0.00025 20.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KZN83533.1 - 4e-10 39.7 0.0 0.00014 21.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KZN83533.1 - 5.6e-09 35.3 0.0 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 KZN83533.1 - 9.7e-09 34.4 0.0 8.9e-05 21.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KZN83533.1 - 1.3e-08 34.4 0.1 0.0046 16.6 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 KZN83533.1 - 9.9e-08 32.1 0.0 0.0064 16.6 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KZN83533.1 - 3.2e-07 29.9 1.7 0.018 14.4 0.0 3.0 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_25 PF13481.1 KZN83533.1 - 4.7e-07 29.4 3.2 1.2 8.4 0.0 4.6 2 2 2 4 4 4 3 AAA domain AAA_28 PF13521.1 KZN83533.1 - 9.2e-07 28.9 0.0 0.019 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN83533.1 - 1e-06 29.0 0.0 0.012 15.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KZN83533.1 - 1.5e-06 27.8 0.0 0.0053 16.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KZN83533.1 - 1.6e-06 27.4 0.3 0.038 13.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KZN83533.1 - 5.3e-06 26.2 0.2 0.61 9.7 0.0 4.1 3 1 1 4 4 4 2 NACHT domain KaiC PF06745.8 KZN83533.1 - 8.1e-06 25.1 0.1 0.27 10.3 0.0 3.4 2 1 1 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 KZN83533.1 - 2.3e-05 24.3 0.0 0.0036 17.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.11 KZN83533.1 - 2.4e-05 23.6 0.0 0.065 12.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 KZN83533.1 - 6.1e-05 23.0 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KZN83533.1 - 6.2e-05 23.3 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SKI PF01202.17 KZN83533.1 - 8.5e-05 22.4 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activat PF00158.21 KZN83533.1 - 0.0001 21.8 0.0 0.26 10.7 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KZN83533.1 - 0.00019 21.2 0.0 1.9 8.1 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KZN83533.1 - 0.00039 19.3 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 KZN83533.1 - 0.00077 18.2 0.0 0.27 9.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 KZN83533.1 - 0.0012 17.7 0.1 0.68 8.6 0.0 3.0 2 1 0 2 2 2 1 AFG1-like ATPase ResIII PF04851.10 KZN83533.1 - 0.0012 18.6 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KZN83533.1 - 0.0019 17.1 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 KZN83533.1 - 0.0022 17.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KZN83533.1 - 0.0055 16.2 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KZN83533.1 - 0.0062 16.1 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KZN83533.1 - 0.0072 15.2 0.0 0.078 11.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KZN83533.1 - 0.013 15.2 0.0 2 8.0 0.0 3.0 2 1 1 3 3 3 0 NTPase ATP-synt_ab PF00006.20 KZN83533.1 - 0.014 14.9 0.0 1.9 7.9 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 KZN83533.1 - 0.016 14.2 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KZN83533.1 - 0.019 14.5 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KZN83533.1 - 0.036 13.2 0.0 24 4.0 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CPT PF07931.7 KZN83533.1 - 0.04 13.5 0.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.11 KZN83533.1 - 0.043 12.9 0.0 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 KZN83533.1 - 0.17 11.0 0.1 42 3.2 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MSA-2c PF12238.3 KZN83533.1 - 6.2 6.4 6.0 50 3.4 4.2 2.2 1 1 0 1 1 1 0 Merozoite surface antigen 2c Snf7 PF03357.16 KZN83534.1 - 1.5e-10 40.7 1.6 2.1e-10 40.2 1.1 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 KZN83534.1 - 0.048 13.6 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PITH PF06201.8 KZN83535.1 - 5.5e-43 146.3 0.0 6.7e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain OB_NTP_bind PF07717.11 KZN83536.1 - 2.5e-23 82.0 0.0 4.6e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KZN83536.1 - 2.2e-20 72.5 0.1 4.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN83536.1 - 1.3e-12 47.4 0.0 2.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KZN83536.1 - 3.1e-06 27.3 0.0 7.6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KZN83536.1 - 3.1e-05 23.5 0.0 7.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KZN83536.1 - 0.0034 16.3 0.1 0.0094 14.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 KZN83536.1 - 0.013 14.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KZN83536.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KZN83536.1 - 0.018 14.9 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KZN83536.1 - 0.044 12.8 0.6 0.19 10.8 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KZN83536.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CUE PF02845.11 KZN83537.1 - 8e-11 41.2 0.0 1.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain MOZART1 PF12554.3 KZN83538.1 - 1.7e-24 85.0 1.1 2e-24 84.7 0.7 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 KZN83538.1 - 0.011 15.8 0.2 0.028 14.5 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF1844 PF08899.6 KZN83538.1 - 0.012 15.5 0.4 0.017 15.0 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) WXG100 PF06013.7 KZN83538.1 - 0.044 13.8 0.1 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF3926 PF13080.1 KZN83538.1 - 0.17 11.4 0.9 0.22 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Metallophos PF00149.23 KZN83539.1 - 0.0015 17.9 0.7 0.0054 16.1 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.19 KZN83540.1 - 2e-11 43.7 0.1 3.1e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KZN83540.1 - 2.7e-09 36.6 0.0 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KZN83540.1 - 2e-07 31.0 0.1 2.9e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN83540.1 - 2.1e-06 27.8 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KZN83540.1 - 0.00018 21.1 0.4 0.00027 20.5 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN83540.1 - 0.00061 19.6 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KZN83540.1 - 0.00081 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN83540.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KZN83540.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain He_PIG PF05345.7 KZN83541.1 - 1.9e-15 56.6 4.9 0.00024 21.0 0.0 4.4 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 KZN83541.1 - 7.5e-08 31.5 0.4 1.5e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3328 PF11807.3 KZN83541.1 - 0.11 12.1 0.6 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) PP2C PF00481.16 KZN83542.1 - 4.4e-80 268.7 0.0 6.8e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KZN83542.1 - 0.00026 20.4 0.0 0.00067 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 KZN83543.1 - 7.2e-21 74.8 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase EamA PF00892.15 KZN83544.1 - 2.6e-16 59.8 28.9 1.6e-11 44.3 5.7 3.7 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 KZN83544.1 - 6.5e-06 26.3 3.1 6.5e-06 26.3 2.2 3.9 2 2 2 4 4 4 2 Multidrug resistance efflux transporter DUF1253 PF06862.7 KZN83545.1 - 6e-161 535.7 0.0 7.7e-161 535.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) JAB PF01398.16 KZN83546.1 - 8.5e-17 60.9 0.2 2.7e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KZN83546.1 - 4.3e-16 59.0 0.2 7.8e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function TFIID-18kDa PF02269.11 KZN83547.1 - 1.1e-23 82.8 0.0 1.7e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 KZN83547.1 - 0.00026 21.1 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KZN83547.1 - 0.00034 20.6 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KZN83547.1 - 0.0037 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KZN83547.1 - 0.004 17.4 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KZN83547.1 - 0.019 15.0 0.8 0.085 12.9 0.1 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 KZN83547.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) cwf18 PF08315.7 KZN83548.1 - 3.5e-42 143.8 4.6 7.1e-42 142.9 3.2 1.5 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.7 KZN83548.1 - 2.4 9.1 8.4 0.26 12.2 0.6 2.5 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component SUZ PF12752.2 KZN83549.1 - 9.2e-20 70.9 0.6 9.2e-20 70.9 0.4 2.4 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 KZN83549.1 - 2.9e-06 26.8 0.0 6.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L16 PF00252.13 KZN83550.1 - 0.063 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e EphA2_TM PF14575.1 KZN83550.1 - 0.1 13.0 0.4 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UCR_Fe-S_N PF10399.4 KZN83550.1 - 0.22 10.6 0.1 0.22 10.6 0.1 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF865 PF05906.6 KZN83550.1 - 2.6 7.7 5.6 1.8 8.1 0.9 2.4 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L17 PF01196.14 KZN83551.1 - 4.4e-30 104.1 0.3 9.6e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 Mg_chelatase_2 PF13335.1 KZN83551.1 - 0.089 13.1 0.9 0.089 13.1 0.6 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Bac_small_YrzI PF09501.5 KZN83552.1 - 0.41 10.5 3.7 0.72 9.7 0.6 2.2 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Ribosom_S12_S23 PF00164.20 KZN83554.1 - 1.5e-40 137.4 0.4 1.7e-40 137.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 KZN83555.1 - 6.7e-64 215.5 0.2 2.9e-38 131.4 0.0 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family NIF PF03031.13 KZN83556.1 - 1.3e-54 184.2 0.0 2.3e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Metallophos PF00149.23 KZN83557.1 - 3.4e-08 33.1 0.5 2e-07 30.6 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN83557.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_76 PF03663.9 KZN83558.1 - 4.7e-140 467.1 24.5 5.9e-140 466.8 17.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 KZN83559.1 - 2.6e-30 105.3 54.6 4.6e-29 101.2 22.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83559.1 - 1.1e-11 44.0 22.1 2.9e-11 42.6 15.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Nucleoside_tran PF01733.13 KZN83559.1 - 0.0048 16.1 0.9 0.0048 16.1 0.6 1.7 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KZN83560.1 - 2.2e-31 108.8 34.4 6.8e-31 107.2 23.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily APOC4 PF15119.1 KZN83560.1 - 0.057 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein C4 Symplekin_C PF12295.3 KZN83560.1 - 0.074 12.9 0.0 5.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal DUF912 PF06024.7 KZN83560.1 - 0.092 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MFS_1 PF07690.11 KZN83561.1 - 3.6e-36 124.6 28.9 3.6e-36 124.6 20.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83561.1 - 2.1e-12 46.3 9.7 2.1e-12 46.3 6.7 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KZN83561.1 - 7.1e-06 24.4 4.1 7.1e-06 24.4 2.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KZN83562.1 - 3.2e-21 75.3 0.3 4.2e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TMPIT PF07851.8 KZN83562.1 - 0.06 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sugar_tr PF00083.19 KZN83563.1 - 0.00037 19.1 0.1 0.00038 19.1 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter N2227 PF07942.7 KZN83564.1 - 6.7e-58 195.7 0.0 1.5e-57 194.6 0.0 1.5 2 0 0 2 2 2 1 N2227-like protein Methyltransf_12 PF08242.7 KZN83564.1 - 0.0016 18.8 0.1 0.019 15.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN83564.1 - 0.0031 17.2 0.0 0.0087 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN83564.1 - 0.0052 17.2 0.0 0.015 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN83564.1 - 0.04 14.5 0.0 0.094 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF3106 PF11304.3 KZN83564.1 - 0.076 13.4 1.7 0.2 12.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Methyltransf_26 PF13659.1 KZN83564.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain IFT46_B_C PF12317.3 KZN83564.1 - 0.17 11.2 0.4 0.47 9.7 0.1 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal NFRKB_winged PF14465.1 KZN83564.1 - 0.37 10.6 2.3 0.56 10.0 0.1 2.4 3 1 0 3 3 3 0 NFRKB Winged Helix-like Strep_his_triad PF04270.8 KZN83565.1 - 0.11 12.2 4.3 13 5.6 0.2 3.3 3 0 0 3 3 3 0 Streptococcal histidine triad protein Med3 PF11593.3 KZN83565.1 - 2.6 7.1 11.0 3.5 6.7 7.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2531 PF10748.4 KZN83565.1 - 3.6 6.7 7.9 17 4.6 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2531) HECT PF00632.20 KZN83566.1 - 8.6e-93 310.9 0.0 1.2e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KZN83566.1 - 5.1e-31 106.1 18.0 1.3e-11 44.1 2.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KZN83566.1 - 1.1e-16 60.4 0.0 2.5e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 KZN83567.1 - 8.9e-16 57.2 0.0 1.7e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN83567.1 - 1.5e-14 53.6 0.1 4.5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN83567.1 - 8.9e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 KZN83567.1 - 0.0056 14.6 0.3 0.0061 14.4 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 KZN83567.1 - 0.043 14.0 0.5 0.083 13.1 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.8 KZN83567.1 - 0.045 12.6 4.0 0.064 12.2 2.8 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CASP_C PF08172.7 KZN83567.1 - 0.066 12.2 0.1 0.081 11.9 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal IncA PF04156.9 KZN83567.1 - 0.07 12.7 4.6 0.092 12.3 3.2 1.1 1 0 0 1 1 1 0 IncA protein Nup35_RRM_2 PF14605.1 KZN83567.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif APG6 PF04111.7 KZN83567.1 - 0.11 11.5 2.4 0.12 11.3 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 STAT_alpha PF01017.15 KZN83567.1 - 0.11 12.2 1.5 0.15 11.7 1.0 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain COG6 PF06419.6 KZN83567.1 - 0.12 10.4 0.7 0.16 10.0 0.5 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 BLOC1_2 PF10046.4 KZN83567.1 - 0.13 12.4 1.7 0.2 11.8 1.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pox_A_type_inc PF04508.7 KZN83567.1 - 0.17 11.7 1.1 0.46 10.4 0.6 1.9 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DUF904 PF06005.7 KZN83567.1 - 0.27 11.5 5.3 0.46 10.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Troponin PF00992.15 KZN83567.1 - 0.37 10.8 6.4 0.51 10.3 4.4 1.1 1 0 0 1 1 1 0 Troponin DUF724 PF05266.9 KZN83567.1 - 0.41 10.2 3.6 0.55 9.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.10 KZN83567.1 - 0.51 9.8 4.5 0.79 9.2 3.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.1 KZN83567.1 - 0.57 10.0 2.5 0.77 9.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF947 PF06102.7 KZN83567.1 - 1 9.1 5.0 1.3 8.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Metallophos_2 PF12850.2 KZN83568.1 - 2.9e-10 40.2 0.0 3.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 KZN83569.1 - 7.9e-27 93.9 0.0 1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KZN83569.1 - 0.0017 18.2 0.1 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain MFS_1 PF07690.11 KZN83571.1 - 1e-24 86.9 37.3 1e-24 86.9 25.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KZN83572.1 - 5.7e-08 32.5 10.7 1.2e-07 31.5 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 KZN83573.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Pkinase PF00069.20 KZN83574.1 - 5.9e-10 38.7 0.0 9.7e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KZN83574.1 - 1.8e-06 27.1 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KZN83574.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KZN83574.1 - 0.0029 17.3 0.1 0.0063 16.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KZN83574.1 - 0.0037 16.3 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KZN83574.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KZN83575.1 - 1.1e-10 41.6 0.0 2.8e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN83575.1 - 3e-07 30.2 0.0 8.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN83575.1 - 0.0005 18.8 0.1 0.0019 16.9 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 KZN83575.1 - 0.0053 15.9 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain DUF3297 PF11730.3 KZN83575.1 - 0.0068 16.0 0.9 0.014 15.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3297) EcKinase PF02958.15 KZN83575.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_ser-thr_kin PF05445.6 KZN83575.1 - 0.057 12.2 0.3 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Tox-URI2 PF15653.1 KZN83575.1 - 0.075 13.2 1.5 0.18 11.9 1.0 1.6 1 0 0 1 1 1 0 URI fold toxin 2 AcetylCoA_hyd_C PF13336.1 KZN83575.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Zn_clus PF00172.13 KZN83576.1 - 0.0003 20.6 7.1 0.0003 20.6 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF547 PF04784.9 KZN83576.1 - 0.031 14.1 0.0 0.081 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF547 MLANA PF14991.1 KZN83577.1 - 0.02 14.9 1.3 1.6 8.7 0.2 2.1 1 1 1 2 2 2 0 Protein melan-A HHH PF00633.18 KZN83578.1 - 0.11 12.1 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lamp PF01299.12 KZN83579.1 - 0.57 9.2 4.3 0.94 8.5 3.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF202 PF02656.10 KZN83581.1 - 2.4e-12 46.9 4.7 2.4e-12 46.9 3.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 KZN83581.1 - 0.013 15.2 0.5 0.021 14.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4117 PF13491.1 KZN83581.1 - 0.044 13.2 1.9 0.055 12.9 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) DUF2207 PF09972.4 KZN83581.1 - 0.067 11.7 1.2 0.073 11.6 0.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 KZN83581.1 - 7.6 5.8 6.8 3.1 7.1 1.0 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) GMC_oxred_N PF00732.14 KZN83582.1 - 7.9e-54 182.8 0.0 1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN83582.1 - 6.7e-31 107.5 0.1 1.2e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN83582.1 - 8e-06 24.9 1.5 0.0086 14.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KZN83582.1 - 0.0015 18.6 0.2 1.1 9.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN83582.1 - 0.0045 15.9 0.1 0.0079 15.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KZN83582.1 - 0.0059 15.5 4.4 0.0087 14.9 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN83582.1 - 0.039 13.0 0.6 0.45 9.5 0.1 2.4 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KZN83582.1 - 0.067 13.2 0.3 0.2 11.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.13 KZN83583.1 - 4.8e-10 39.1 10.0 8.3e-10 38.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN83583.1 - 7.5e-07 28.0 0.3 1e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HATPase_c PF02518.21 KZN83585.1 - 1.3e-12 47.3 0.0 2.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BSMAP PF12280.3 KZN83585.1 - 0.6 9.9 2.6 0.69 9.7 0.2 2.0 1 1 1 2 2 2 0 Brain specific membrane anchored protein Methyltransf_11 PF08241.7 KZN83586.1 - 1e-12 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN83586.1 - 2.6e-11 44.0 0.0 4.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN83586.1 - 4.3e-09 36.1 0.0 6.3e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN83586.1 - 8.4e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN83586.1 - 8.2e-08 32.6 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN83586.1 - 3.1e-07 30.2 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN83586.1 - 4.9e-06 26.5 0.2 1.2e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN83586.1 - 0.00013 21.1 0.1 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KZN83586.1 - 0.00038 19.8 0.1 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KZN83586.1 - 0.00042 19.5 0.5 0.00062 18.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KZN83586.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 KZN83586.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ImmE5 PF11480.3 KZN83586.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Colicin-E5 Imm protein N6_N4_Mtase PF01555.13 KZN83586.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.4 2 0 0 2 2 2 0 DNA methylase CheR PF01739.13 KZN83586.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.17 KZN83587.1 - 1.1e-53 182.4 0.0 1.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ATP1G1_PLM_MAT8 PF02038.11 KZN83588.1 - 0.11 11.5 1.0 0.23 10.5 0.7 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family FAD_binding_4 PF01565.18 KZN83589.1 - 4.8e-23 81.1 0.3 8.8e-23 80.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN83589.1 - 0.0036 17.1 0.2 0.0081 16.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.8 KZN83593.1 - 5.7e-18 65.0 0.0 1.3e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN83593.1 - 1.7e-16 60.7 0.0 2.9e-16 59.9 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KZN83593.1 - 9.7e-09 35.0 0.0 5.8e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KZN83593.1 - 4.6e-05 22.5 0.0 5.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KZN83593.1 - 0.00017 21.5 0.1 0.00036 20.4 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83593.1 - 0.00059 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KZN83593.1 - 0.0026 16.7 0.0 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KZN83593.1 - 0.0044 15.9 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 KZN83593.1 - 0.0049 16.9 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KZN83593.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KZN83593.1 - 0.013 15.3 0.8 0.086 12.7 0.2 2.4 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KZN83593.1 - 0.017 15.5 0.3 0.043 14.2 0.1 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KZN83593.1 - 0.039 12.6 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.14 KZN83593.1 - 0.087 12.6 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Semialdhyde_dh PF01118.19 KZN83593.1 - 0.13 12.5 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain COesterase PF00135.23 KZN83594.1 - 9.1e-68 229.2 0.0 1.2e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN83594.1 - 5.2e-06 26.1 0.1 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN83594.1 - 0.0012 18.0 0.0 0.0039 16.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Pkinase PF00069.20 KZN83595.1 - 2.2e-28 99.1 0.0 1.5e-27 96.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83595.1 - 8.7e-08 31.5 0.0 0.012 14.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_3 PF00933.16 KZN83597.1 - 3e-75 252.9 0.0 4.5e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN83597.1 - 2.8e-62 210.2 0.0 4.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN83597.1 - 3.2e-25 87.8 0.0 6.8e-25 86.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KZN83597.1 - 1.3e-14 54.0 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain T6SS-SciN PF12790.2 KZN83597.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion lipoprotein Sugar_tr PF00083.19 KZN83598.1 - 5.6e-73 246.0 23.0 6.7e-73 245.7 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83598.1 - 6.4e-22 77.7 18.8 6.4e-22 77.7 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 KZN83600.1 - 2.3e-19 69.1 5.1 4.5e-19 68.2 3.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN83600.1 - 7.4e-11 41.7 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN83600.1 - 0.00036 19.7 0.1 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN83600.1 - 0.0015 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KZN83600.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF521 PF04412.8 KZN83601.1 - 1.8e-144 481.1 0.0 2.4e-144 480.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 KZN83601.1 - 1.9e-30 104.3 0.0 4.2e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF126 Aminotran_1_2 PF00155.16 KZN83602.1 - 2.3e-51 174.8 0.0 2.8e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Reo_sigmaC PF04582.7 KZN83604.1 - 0.23 10.6 6.8 0.14 11.2 3.0 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2663 PF10864.3 KZN83604.1 - 0.25 11.5 3.1 0.51 10.5 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) IncA PF04156.9 KZN83604.1 - 6.4 6.3 39.3 7.2 6.1 6.6 3.5 2 1 1 3 3 3 0 IncA protein MACPF PF01823.14 KZN83605.1 - 4.2e-11 42.9 1.5 8e-11 42.0 1.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Con-6 PF10346.4 KZN83606.1 - 8e-28 95.5 2.2 1.6e-16 59.4 0.2 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 KZN83606.1 - 0.07 12.6 1.3 0.21 11.0 0.2 1.9 1 1 0 2 2 2 0 SpoIIIAH-like protein MIP PF00230.15 KZN83607.1 - 3.2e-33 115.1 4.1 3.8e-33 114.8 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF606 PF04657.8 KZN83607.1 - 0.092 12.8 3.3 0.2 11.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF606 Tad PF13400.1 KZN83607.1 - 0.16 12.0 2.0 20 5.3 0.6 3.1 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3325 PF11804.3 KZN83607.1 - 0.46 10.4 0.0 0.46 10.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3325) Gly-zipper_Omp PF13488.1 KZN83607.1 - 0.57 9.8 3.1 8 6.1 0.0 3.1 3 0 0 3 3 3 0 Glycine zipper PALP PF00291.20 KZN83608.1 - 1.4e-53 182.1 0.0 1.6e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme XET_C PF06955.7 KZN83609.1 - 0.062 13.0 0.8 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus BNR PF02012.15 KZN83610.1 - 0.022 14.5 0.2 0.081 12.8 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Tctex-1 PF03645.8 KZN83611.1 - 1.2e-32 111.7 0.0 1.4e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.27 KZN83612.1 - 5.1e-42 140.2 14.0 8.4e-12 44.4 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KZN83612.1 - 2.1e-06 26.1 3.0 0.42 8.6 0.1 3.9 3 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 KZN83612.1 - 0.14 10.3 0.0 0.23 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Hira PF07569.6 KZN83612.1 - 0.2 10.8 0.4 2.6 7.1 0.0 2.8 2 1 2 4 4 4 0 TUP1-like enhancer of split Mod_r PF07200.8 KZN83613.1 - 0.014 15.2 5.5 0.024 14.5 3.8 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Vps5 PF09325.5 KZN83613.1 - 0.02 14.1 3.0 0.031 13.5 2.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like BLOC1_2 PF10046.4 KZN83613.1 - 0.024 14.7 2.3 0.047 13.8 1.6 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.1 KZN83613.1 - 0.079 12.5 3.3 0.086 12.4 1.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain of unknown function DUF3584 PF12128.3 KZN83613.1 - 0.11 9.8 8.0 0.14 9.4 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 KZN83613.1 - 0.19 11.6 11.8 0.26 11.1 8.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KZN83613.1 - 1.1 8.1 10.7 1.5 7.6 7.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2664 PF10867.3 KZN83613.1 - 1.1 9.8 4.1 0.35 11.5 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) TilS PF09179.6 KZN83614.1 - 0.21 11.6 2.9 2 8.5 1.0 2.5 1 1 1 2 2 2 0 TilS substrate binding domain LysM PF01476.15 KZN83615.1 - 3.5e-05 23.6 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 LysM domain MFS_1 PF07690.11 KZN83616.1 - 4.4e-31 107.8 38.1 1.1e-29 103.2 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83616.1 - 2.8e-08 32.7 8.8 2.8e-08 32.7 6.1 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KZN83616.1 - 1.6e-07 29.9 1.6 1.6e-07 29.9 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AIP3 PF03915.8 KZN83617.1 - 1e-156 522.1 1.2 1e-156 522.1 0.8 2.2 3 0 0 3 3 3 1 Actin interacting protein 3 Lectin_N PF03954.9 KZN83617.1 - 0.0015 17.9 0.1 0.0015 17.9 0.0 3.0 4 0 0 4 4 4 1 Hepatic lectin, N-terminal domain LsmAD PF06741.8 KZN83618.1 - 1.9e-26 91.9 3.5 4.2e-26 90.8 1.6 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 KZN83618.1 - 1.4e-15 57.0 0.0 3.5e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.20 KZN83619.1 - 1.3e-09 37.5 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KZN83619.1 - 1.4e-09 37.2 2.1 0.03 14.3 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 KZN83619.1 - 1.1e-07 31.2 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KZN83619.1 - 0.0014 19.0 0.4 2.3 8.8 0.0 3.1 2 1 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.15 KZN83619.1 - 0.0014 17.0 0.0 0.002 16.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KZN83619.1 - 0.0041 16.9 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KZN83619.1 - 0.0048 15.9 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.1 KZN83619.1 - 0.0093 16.2 0.1 0.18 12.0 0.1 2.7 1 1 1 2 2 2 1 HEAT repeats CoA_trans PF01144.18 KZN83619.1 - 0.02 14.0 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Ipi1_N PF12333.3 KZN83619.1 - 0.028 14.3 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Amino_oxidase PF01593.19 KZN83621.1 - 4e-59 200.8 0.1 1.5e-43 149.5 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN83621.1 - 3.1e-12 46.3 0.3 5.5e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN83621.1 - 1.4e-09 37.3 1.1 2.8e-06 26.4 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN83621.1 - 5.2e-06 26.7 0.5 1.2e-05 25.5 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN83621.1 - 1.2e-05 24.4 1.4 0.016 14.1 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KZN83621.1 - 1.3e-05 25.4 0.6 0.0017 18.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN83621.1 - 1.4e-05 24.1 3.0 2.4e-05 23.3 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KZN83621.1 - 2.2e-05 23.6 0.4 3.9e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KZN83621.1 - 3.5e-05 22.4 1.2 0.00046 18.7 1.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KZN83621.1 - 0.00012 21.2 0.5 0.00064 18.8 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN83621.1 - 0.00022 21.2 0.1 0.0004 20.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN83621.1 - 0.00031 19.9 0.5 0.00041 19.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN83621.1 - 0.00065 19.4 0.2 0.023 14.4 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 KZN83621.1 - 0.0076 15.1 0.6 0.012 14.5 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KZN83621.1 - 1.1 8.8 2.7 0.65 9.5 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF61 PF01886.11 KZN83622.1 - 0.075 12.8 0.3 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF61 Chromate_transp PF02417.10 KZN83623.1 - 3.9e-33 114.4 35.4 6.3e-30 103.9 7.7 2.5 3 0 0 3 3 3 2 Chromate transporter zf-MYND PF01753.13 KZN83625.1 - 1.2e-09 37.8 11.1 1.9e-09 37.2 7.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KZN83625.1 - 1.8 8.4 5.9 3.5 7.5 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 HATPase_c PF02518.21 KZN83630.1 - 5.7e-24 83.9 0.0 9.4e-23 80.0 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN83630.1 - 8.8e-23 80.4 0.3 2.2e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KZN83630.1 - 1e-19 70.2 0.1 2.6e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KZN83630.1 - 2e-18 66.6 0.0 3e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KZN83630.1 - 8.9e-16 57.6 0.0 5.2e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KZN83630.1 - 1.5e-11 44.2 0.0 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold Gemin7 PF11095.3 KZN83630.1 - 0.024 14.3 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF3454 PF11936.3 KZN83631.1 - 0.091 12.9 1.6 0.18 11.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) Fungal_trans PF04082.13 KZN83632.1 - 3.5e-23 81.8 4.2 5e-23 81.2 2.4 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83632.1 - 9.3e-08 31.8 9.5 9.3e-08 31.8 6.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferritin_2 PF13668.1 KZN83633.1 - 1.6e-17 63.7 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 KZN83634.1 - 1.7e-06 26.8 3.8 3e-06 26.0 2.6 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter GFA PF04828.9 KZN83635.1 - 6.8e-11 41.9 0.7 1.4e-10 40.9 0.5 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Thioredoxin_4 PF13462.1 KZN83636.1 - 1.7e-09 37.9 0.0 2.8e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KZN83636.1 - 0.0037 16.8 0.3 0.48 9.9 0.0 2.6 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 KZN83636.1 - 0.024 14.8 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain LysM PF01476.15 KZN83637.1 - 2.4e-15 56.1 0.0 3e-06 27.0 0.0 3.2 3 0 0 3 3 3 3 LysM domain Antimicrobial_6 PF08036.6 KZN83637.1 - 0.0042 16.7 3.2 0.2 11.4 0.4 2.7 2 0 0 2 2 2 2 Diapausin family of antimicrobial peptide SARA PF11409.3 KZN83637.1 - 1.6 8.7 8.5 0.57 10.1 0.1 3.2 3 0 0 3 3 3 0 Smad anchor for receptor activation (SARA) LysM PF01476.15 KZN83640.1 - 9.4e-22 76.6 0.5 1.2e-06 28.3 0.0 3.2 3 0 0 3 3 3 3 LysM domain Sporozoite_P67 PF05642.6 KZN83640.1 - 0.23 9.2 4.6 0.32 8.7 3.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UPF0203 PF05254.7 KZN83640.1 - 2.3 8.1 4.9 12 5.8 0.4 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Lamp PF01299.12 KZN83640.1 - 3.6 6.6 12.8 2.9 6.9 2.8 2.2 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Hydrophobin PF01185.13 KZN83641.1 - 5.8e-06 26.6 7.9 8.7e-06 26.1 5.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN83641.1 - 0.051 13.6 1.8 0.051 13.6 1.2 2.3 2 0 0 2 2 2 0 Granulin UBN2_3 PF14244.1 KZN83642.1 - 0.00032 20.2 0.2 0.00051 19.6 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PDEase_I_N PF08499.7 KZN83642.1 - 0.087 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal CBM_14 PF01607.19 KZN83644.1 - 2.2e-07 30.7 3.2 3.3e-07 30.1 2.2 1.4 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3425 PF11905.3 KZN83645.1 - 9.6e-35 119.4 0.5 9.6e-35 119.4 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KZN83645.1 - 0.081 12.8 13.2 0.83 9.6 3.7 2.8 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.10 KZN83645.1 - 0.15 11.9 9.7 0.23 11.3 1.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Herpes_UL6 PF01763.11 KZN83645.1 - 0.15 10.2 5.2 0.19 9.8 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like MFS_1 PF07690.11 KZN83646.1 - 8.5e-49 166.1 39.8 8.5e-49 166.1 27.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83646.1 - 1.9e-10 39.9 34.3 6.7e-10 38.1 24.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KZN83646.1 - 0.014 13.5 0.4 0.014 13.5 0.3 2.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family UBN2_3 PF14244.1 KZN83647.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_7 PF02796.10 KZN83647.1 - 0.089 12.6 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Acetyltransf_1 PF00583.19 KZN83649.1 - 2.9e-13 49.6 0.1 4.8e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KZN83649.1 - 8.3e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KZN83649.1 - 0.0034 17.4 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN83649.1 - 0.0057 16.5 0.3 0.0088 15.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN83649.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SUR7 PF06687.7 KZN83651.1 - 1.6e-48 165.0 7.1 1.9e-48 164.8 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KZN83651.1 - 0.28 11.0 16.2 0.057 13.2 8.3 1.9 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 adh_short PF00106.20 KZN83652.1 - 1.1e-25 90.4 2.1 1.4e-25 90.1 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN83652.1 - 2.4e-25 89.7 0.0 2.8e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN83652.1 - 2.5e-13 50.0 0.7 3.6e-13 49.5 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN83652.1 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN83652.1 - 0.0045 15.9 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HLH PF00010.21 KZN83653.1 - 1.6e-12 46.9 0.0 6.2e-12 45.0 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 KZN83654.1 - 4.9e-34 116.9 17.3 7.5e-34 116.3 12.0 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KZN83654.1 - 0.00038 19.4 0.2 0.00081 18.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M50 tRNA_lig_CPD PF08302.6 KZN83655.1 - 2.6e-94 315.2 0.0 3.9e-94 314.6 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 KZN83655.1 - 2.1e-78 262.8 0.0 3.4e-78 262.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KZN83655.1 - 5.1e-49 166.3 0.0 9e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 KZN83655.1 - 0.057 13.3 0.1 0.2 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 KZN83656.1 - 5.3e-13 48.7 0.1 2.5e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN83656.1 - 1.7e-08 34.7 0.0 1.6e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KZN83656.1 - 9.5e-06 25.1 0.8 0.00033 20.3 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KZN83656.1 - 2e-05 24.8 0.3 0.00015 21.9 0.1 2.0 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN83656.1 - 4e-05 23.4 0.6 0.00038 20.4 0.1 2.7 3 1 0 3 3 3 1 Ankyrin repeat YejG PF13989.1 KZN83656.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 YejG-like protein TipAS PF07739.8 KZN83656.1 - 0.067 13.5 0.6 6.1 7.1 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Mod_r PF07200.8 KZN83657.1 - 1.7e-10 40.9 1.8 2.5e-10 40.4 1.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RcbX PF02341.10 KZN83657.1 - 0.014 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 RbcX protein Fib_alpha PF08702.5 KZN83657.1 - 0.046 13.8 0.9 0.084 13.0 0.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family KIAA1430 PF13879.1 KZN83657.1 - 0.1 13.0 1.4 0.22 11.9 1.0 1.5 1 0 0 1 1 1 0 KIAA1430 homologue PAP2 PF01569.16 KZN83658.1 - 4.9e-22 77.9 3.8 4.9e-22 77.9 2.6 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF1206 PF06724.6 KZN83658.1 - 0.0045 16.7 8.1 0.037 13.7 0.1 3.4 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1206) UPF0182 PF03699.8 KZN83658.1 - 0.097 10.5 0.2 0.13 10.1 0.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Spatacsin_C PF14649.1 KZN83659.1 - 0.04 12.7 0.3 0.06 12.2 0.2 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus UCR_Fe-S_N PF10399.4 KZN83659.1 - 0.13 11.4 0.1 6.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Grp1_Fun34_YaaH PF01184.14 KZN83661.1 - 1.3e-09 37.6 5.4 1.5e-09 37.4 3.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Amino_oxidase PF01593.19 KZN83662.1 - 3.1e-33 115.5 0.0 6.1e-33 114.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN83662.1 - 2.5e-05 24.2 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KZN83662.1 - 0.0042 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAGAT PF03982.8 KZN83662.1 - 0.15 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase Ctr PF04145.10 KZN83663.1 - 1.7e-35 122.2 4.8 2e-35 121.9 3.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family UPF0016 PF01169.14 KZN83663.1 - 0.2 11.8 2.8 0.96 9.6 1.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 Ferric_reduct PF01794.14 KZN83664.1 - 2.9e-22 79.0 10.0 7.2e-22 77.7 6.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KZN83664.1 - 7.1e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KZN83664.1 - 7e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KZN83664.1 - 2.3e-06 28.1 0.0 7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CRAL_TRIO PF00650.15 KZN83665.1 - 4.1e-45 153.1 0.0 6.6e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN83665.1 - 5.3e-13 48.8 0.0 1.7e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KZN83665.1 - 1.3e-12 47.8 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_tranf_2_3 PF13641.1 KZN83666.1 - 7e-33 114.3 0.0 1e-32 113.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KZN83666.1 - 1.9e-19 70.1 0.1 2.8e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KZN83666.1 - 2.8e-11 43.3 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KZN83666.1 - 3.6e-06 26.3 0.0 5.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Oxidored_FMN PF00724.15 KZN83667.1 - 1.9e-68 231.0 0.0 2.4e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.16 KZN83668.1 - 1.8e-54 184.5 0.0 2.6e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 KZN83668.1 - 4.6e-10 39.6 0.0 8.5e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN83668.1 - 0.00071 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain HTH_Tnp_1 PF01527.15 KZN83668.1 - 0.045 13.7 0.0 0.69 9.9 0.0 2.6 2 0 0 2 2 2 0 Transposase GFA PF04828.9 KZN83669.1 - 0.00018 21.4 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 KZN83670.1 - 1.3e-05 24.9 0.8 1.8e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KZN83670.1 - 0.039 13.9 2.1 0.11 12.5 1.5 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KZN83670.1 - 0.26 11.3 4.1 2.5 8.1 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 KZN83671.1 - 6.8e-137 456.6 2.9 6.9e-137 456.6 0.0 2.2 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 KZN83671.1 - 0.0035 16.0 0.0 0.0078 14.9 0.0 1.5 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Mago-bind PF09282.5 KZN83671.1 - 7.3 6.2 7.9 0.49 10.0 1.4 2.1 2 0 0 2 2 2 0 Mago binding La PF05383.12 KZN83672.1 - 1e-19 70.0 0.3 1.9e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 La domain RRN9 PF10680.4 KZN83672.1 - 0.19 11.4 5.4 3.3 7.5 0.2 3.2 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor Band_7 PF01145.20 KZN83673.1 - 3.7e-31 108.3 0.9 7.3e-31 107.4 0.6 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KZN83673.1 - 0.0052 16.3 0.1 0.0096 15.4 0.0 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family HTH_5 PF01022.15 KZN83675.1 - 0.076 12.6 0.2 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PSI_PsaJ PF01701.13 KZN83677.1 - 0.032 13.9 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ Hira PF07569.6 KZN83678.1 - 3.6e-83 278.1 0.0 7.3e-83 277.0 0.0 1.5 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KZN83678.1 - 2.8e-40 134.7 19.4 1.5e-07 30.9 0.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 KZN83678.1 - 7.5e-10 38.0 0.0 2.6e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KZN83678.1 - 0.00018 21.0 0.3 1.6 8.4 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KZN83678.1 - 0.1 10.3 0.0 0.25 9.1 0.0 1.4 1 1 0 1 1 1 0 IKI3 family YchF-GTPase_C PF06071.8 KZN83679.1 - 9.2e-34 115.0 0.3 1.9e-33 114.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KZN83679.1 - 2.3e-12 46.8 0.0 4.8e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN83679.1 - 0.0007 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KZN83679.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 TGS domain SecA_PP_bind PF01043.15 KZN83679.1 - 0.0084 16.4 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 SecA preprotein cross-linking domain AAA_14 PF13173.1 KZN83679.1 - 0.033 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1955 PF09205.5 KZN83679.1 - 0.046 13.2 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) PUA PF01472.15 KZN83680.1 - 1.1e-13 50.6 0.1 1.6e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 PUA domain GPI-anchored PF10342.4 KZN83683.1 - 9.3e-20 70.9 2.1 9.3e-20 70.9 1.4 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF605 PF04652.11 KZN83683.1 - 0.32 10.3 9.2 0.33 10.2 6.4 1.1 1 0 0 1 1 1 0 Vta1 like Alpha-amylase PF00128.19 KZN83684.1 - 1.2e-29 103.7 0.0 3.6e-29 102.1 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KZN83684.1 - 3.7e-06 25.0 0.2 0.088 10.5 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase PF00128.19 KZN83685.1 - 2.5e-55 188.1 1.2 3.5e-55 187.6 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KZN83685.1 - 8.6e-33 112.2 0.1 1.6e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_transf_17 PF04724.8 KZN83685.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 Alpha-amylase PF00128.19 KZN83686.1 - 1.5e-16 60.6 0.8 1.5e-16 60.6 0.5 2.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KZN83686.1 - 4e-15 55.9 0.1 8e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KZN83686.1 - 3.7e-06 27.1 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KZN83686.1 - 9.7e-06 25.1 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ank_2 PF12796.2 KZN83687.1 - 2.3e-104 341.9 24.2 5.6e-18 65.0 0.2 9.2 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83687.1 - 8.3e-97 312.5 25.6 2.3e-06 27.1 0.0 17.5 17 0 0 17 17 17 16 Ankyrin repeat Ank_5 PF13857.1 KZN83687.1 - 1.4e-75 247.5 30.4 3.5e-09 36.6 0.4 13.8 3 2 12 15 15 15 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN83687.1 - 2.2e-69 228.7 14.3 1.3e-07 31.9 0.0 13.3 4 3 12 16 16 16 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83687.1 - 3.9e-62 199.9 14.9 0.0012 18.8 0.0 17.5 17 0 0 17 17 17 13 Ankyrin repeat HET PF06985.6 KZN83687.1 - 2.7e-07 30.8 0.5 5e-05 23.4 0.0 2.8 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) YjgF_endoribonc PF14588.1 KZN83687.1 - 0.082 12.8 0.4 45 3.9 0.0 4.0 2 1 0 3 3 3 0 YjgF/chorismate_mutase-like, putative endoribonuclease Antirestrict PF03230.8 KZN83688.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Antirestriction protein Dala_Dala_lig_C PF07478.8 KZN83689.1 - 4.2e-23 81.7 0.0 6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KZN83689.1 - 5.9e-10 39.1 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN83689.1 - 0.0013 17.5 0.0 0.024 13.3 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KZN83689.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KZN83689.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Phe_hydrox_dim PF07976.7 KZN83690.1 - 9.8e-40 135.9 0.0 1.8e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 KZN83690.1 - 3.7e-32 111.7 0.0 5.2e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KZN83690.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.14 KZN83691.1 - 1e-09 37.9 0.0 1.2e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_12 PF01670.11 KZN83693.1 - 8.5e-56 188.0 3.3 1.4e-55 187.3 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 UBN2_3 PF14244.1 KZN83694.1 - 0.00064 19.3 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF1049 PF06305.6 KZN83695.1 - 0.051 13.0 0.2 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4234 PF14018.1 KZN83695.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) RNase_H PF00075.19 KZN83696.1 - 3.7e-13 49.9 0.0 5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KZN83696.1 - 7.2e-05 22.4 0.1 0.001 18.8 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like VPS9 PF02204.13 KZN83697.1 - 1.2e-17 63.8 0.0 3.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KZN83697.1 - 1.2e-16 60.3 0.1 9.2e-11 41.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN83697.1 - 7.5e-12 45.4 0.0 5.5e-08 33.0 0.0 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN83697.1 - 4.1e-09 36.7 0.0 0.0043 17.5 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83697.1 - 6.6e-08 32.0 0.1 1.8 9.0 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.19 KZN83697.1 - 1.6e-07 31.1 1.7 2.3e-07 30.6 0.2 2.0 2 0 0 2 2 2 1 PX domain Ank PF00023.25 KZN83697.1 - 3.6e-07 29.6 0.3 0.1 12.4 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ribosomal_S11 PF00411.14 KZN83698.1 - 1.2e-06 28.7 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 KZN83699.1 - 1.9e-33 115.5 0.0 6e-33 113.9 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain FHIPEP PF00771.15 KZN83699.1 - 0.076 11.3 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 FHIPEP family NifW PF03206.9 KZN83699.1 - 0.1 12.7 1.2 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 Nitrogen fixation protein NifW MFS_1 PF07690.11 KZN83700.1 - 5.9e-28 97.5 21.2 1.2e-27 96.5 14.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CN_hydrolase PF00795.17 KZN83700.1 - 1.2e-21 76.8 0.0 2.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_3 PF01494.14 KZN83701.1 - 9e-14 51.2 1.1 1.6e-07 30.6 0.9 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN83701.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KZN83701.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KZN83701.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 KZN83702.1 - 1.2e-49 168.7 0.0 1.6e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN83702.1 - 7e-06 25.0 0.3 1.6e-05 23.8 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KZN83702.1 - 3.4e-05 23.1 0.0 0.055 12.6 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KZN83702.1 - 0.00028 20.8 0.1 0.00037 20.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KZN83702.1 - 0.00048 18.7 0.1 0.024 13.1 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 KZN83702.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KZN83702.1 - 0.11 11.6 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF3085 PF11284.3 KZN83702.1 - 0.16 12.1 0.1 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) Epimerase PF01370.16 KZN83703.1 - 1.6e-15 57.1 0.1 2.4e-15 56.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN83703.1 - 5.6e-13 48.2 0.0 1e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN83703.1 - 7.7e-12 44.6 0.0 2.1e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KZN83703.1 - 1.6e-11 44.5 0.0 4.3e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN83703.1 - 4.1e-06 26.8 0.7 7.2e-06 26.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN83703.1 - 0.00013 20.9 0.0 0.00027 19.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KZN83703.1 - 0.00028 20.2 0.1 0.00054 19.2 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KZN83703.1 - 0.0004 20.0 0.4 0.00078 19.1 0.3 1.4 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 KZN83704.1 - 2e-34 118.8 34.4 2.8e-34 118.4 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KZN83704.1 - 0.0012 16.9 0.4 0.0026 15.9 0.3 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 KZN83705.1 - 2.4e-23 82.7 0.0 3.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KZN83705.1 - 1.6e-08 34.4 1.3 1.6e-08 34.4 0.9 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN83705.1 - 2e-07 30.2 3.6 1.3e-06 27.5 1.8 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN83705.1 - 2.1e-05 23.6 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KZN83705.1 - 3.2e-05 23.2 0.1 4.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN83705.1 - 5.9e-05 22.0 4.4 9.6e-05 21.3 2.9 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN83705.1 - 9.5e-05 22.3 1.1 0.00014 21.7 0.8 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN83705.1 - 0.00069 19.9 0.5 0.0018 18.6 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN83705.1 - 0.0015 17.4 0.7 0.0022 16.9 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KZN83705.1 - 0.0017 18.4 0.3 0.0036 17.3 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN83705.1 - 0.004 15.8 0.1 0.022 13.3 0.0 2.1 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 KZN83705.1 - 0.0073 14.8 1.1 0.0073 14.8 0.8 1.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KZN83705.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KZN83705.1 - 0.018 14.7 0.2 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KZN83705.1 - 0.018 14.1 0.1 0.082 11.9 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.19 KZN83705.1 - 0.021 13.9 1.3 0.065 12.2 0.5 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KZN83705.1 - 0.033 13.9 0.7 0.069 12.9 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Rossmann-like PF10727.4 KZN83705.1 - 0.047 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 KZN83705.1 - 0.13 11.9 0.3 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KZN83706.1 - 7.9e-51 172.8 5.2 1.1e-50 172.3 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83706.1 - 6.3e-11 42.0 36.1 2.8e-05 23.9 11.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KZN83707.1 - 1.1e-60 204.3 59.0 4.6e-34 117.4 10.7 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KZN83707.1 - 8.1e-39 133.0 0.0 2.8e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN83707.1 - 4.4e-25 87.3 0.3 6.7e-21 73.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter AAA_21 PF13304.1 KZN83707.1 - 6.9e-07 29.5 0.1 0.0094 15.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KZN83707.1 - 7.7e-06 25.4 0.0 0.0031 16.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN83707.1 - 2.8e-05 23.3 0.0 0.00042 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KZN83707.1 - 9.5e-05 21.5 4.0 9.5e-05 21.5 2.8 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 KZN83707.1 - 0.00019 20.8 0.6 0.0044 16.5 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN83707.1 - 0.00065 19.7 0.2 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KZN83707.1 - 0.0033 17.5 0.0 1.6 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KZN83707.1 - 0.009 15.9 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KZN83707.1 - 0.019 14.3 0.1 5 6.4 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KZN83707.1 - 0.079 12.5 0.1 5.4 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KZN83707.1 - 0.081 12.3 0.2 0.65 9.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KZN83707.1 - 0.082 12.6 0.0 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 KZN83707.1 - 0.085 12.0 0.0 15 4.6 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MRVI1 PF05781.7 KZN83707.1 - 0.092 11.1 0.5 0.14 10.5 0.3 1.1 1 0 0 1 1 1 0 MRVI1 protein AAA_18 PF13238.1 KZN83707.1 - 0.1 12.9 0.1 11 6.3 0.0 2.9 4 0 0 4 4 2 0 AAA domain DUF964 PF06133.6 KZN83707.1 - 0.13 12.2 0.3 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF87 PF01935.12 KZN83707.1 - 0.23 11.2 0.1 26 4.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 KZN83707.1 - 0.24 10.4 0.0 2.1 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KZN83707.1 - 0.25 12.1 0.0 20 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KZN83707.1 - 0.33 11.2 1.3 0.65 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KZN83708.1 - 4.4e-17 61.8 0.0 6.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83708.1 - 8.7e-09 35.1 10.0 1.7e-08 34.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 KZN83709.1 - 6.7e-21 73.7 9.2 1.1e-15 57.0 3.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KZN83709.1 - 1.5e-15 55.9 7.7 2.5e-06 26.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KZN83709.1 - 2.2e-14 52.0 10.8 2.5e-05 23.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN83709.1 - 4.6e-09 35.4 4.0 0.00046 19.7 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN83709.1 - 1.4e-08 35.1 11.9 1.8e-06 28.4 4.7 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN83709.1 - 3.1e-08 33.1 2.4 0.0014 18.6 0.2 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN83709.1 - 6.2e-07 28.7 2.4 0.033 13.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN83709.1 - 3e-06 27.0 7.7 0.0019 18.1 1.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN83709.1 - 9.7e-06 25.7 8.3 0.064 13.9 1.4 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KZN83709.1 - 1.8e-05 24.9 7.2 0.0013 19.0 3.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN83709.1 - 0.00035 20.3 2.9 0.0095 15.7 1.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KZN83709.1 - 0.00043 20.6 1.6 0.0037 17.5 0.5 2.3 2 0 0 2 2 2 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 KZN83709.1 - 0.0006 19.2 2.1 0.0006 19.2 1.5 1.9 2 0 0 2 2 2 1 XPC-binding domain Apc3 PF12895.2 KZN83709.1 - 0.056 13.5 2.9 1.6 8.8 2.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KZN83709.1 - 0.073 13.5 7.9 0.31 11.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KZN83709.1 - 0.15 11.9 4.9 0.89 9.4 0.2 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KZN83709.1 - 1.2 9.1 6.9 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RIC1 PF07064.8 KZN83710.1 - 2.6e-87 292.5 0.1 4e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 KZN83710.1 - 0.064 13.1 2.5 7.2 6.6 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Aldedh PF00171.17 KZN83711.1 - 2.1e-107 359.3 0.0 2.5e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN83711.1 - 0.093 11.4 0.1 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) MIP-T3 PF10243.4 KZN83712.1 - 1.3 7.3 68.9 1.6 7.1 47.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 KZN83712.1 - 6.3 4.8 73.0 9.3 4.2 50.6 1.2 1 0 0 1 1 1 0 Utp14 protein Aconitase PF00330.15 KZN83714.1 - 6.3e-122 407.3 0.1 1.8e-71 241.0 0.0 2.7 2 1 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN83714.1 - 5.4e-36 123.5 0.0 9.5e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain GHMP_kinases_C PF08544.8 KZN83714.1 - 0.061 13.5 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 GHMP kinases C terminal Methyltransf_6 PF03737.10 KZN83715.1 - 6e-29 100.8 0.0 8.3e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase FliJ PF02050.11 KZN83717.1 - 0.0072 16.3 0.9 0.12 12.4 0.0 2.2 1 1 1 2 2 2 2 Flagellar FliJ protein Bac_luciferase PF00296.15 KZN83718.1 - 2.9e-63 213.8 0.0 3.6e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2961 PF11175.3 KZN83719.1 - 7.9e-88 293.7 6.0 1e-87 293.3 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Glyco_hydro_32N PF00251.15 KZN83721.1 - 7.8e-51 173.2 0.0 1.2e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN83721.1 - 1.1e-07 32.0 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KZN83721.1 - 0.0068 15.7 0.1 0.024 13.9 0.1 1.9 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KZN83721.1 - 0.038 13.7 3.8 0.16 11.9 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Sugar_tr PF00083.19 KZN83722.1 - 1.8e-69 234.5 25.5 2.2e-69 234.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83722.1 - 9.4e-19 67.3 25.1 9.4e-19 67.3 17.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN83722.1 - 1.6e-07 29.9 2.2 2.8e-07 29.1 1.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cytochrome-c551 PF10643.4 KZN83722.1 - 0.053 12.8 0.1 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Inhibitor_I78 PF11720.3 KZN83723.1 - 5.1e-14 51.7 0.0 6.9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KZN83723.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Potato inhibitor I family Alpha-L-AF_C PF06964.7 KZN83724.1 - 9.2e-37 126.5 0.1 1.3e-36 125.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 KZN83725.1 - 4.5e-103 345.2 18.4 5.2e-103 345.0 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83725.1 - 8.1e-35 120.1 20.5 2.1e-25 89.2 1.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nefa_Nip30_N PF10187.4 KZN83726.1 - 8.2e-30 102.9 14.3 8.2e-30 102.9 9.9 2.5 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 KZN83726.1 - 0.057 12.6 22.2 0.068 12.3 15.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Anth_synt_I_N PF04715.8 KZN83726.1 - 4.3 7.3 6.0 2 8.4 1.3 2.3 2 1 0 2 2 2 0 Anthranilate synthase component I, N terminal region DUF4192 PF13830.1 KZN83726.1 - 4.5 6.8 7.8 6.4 6.3 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Aldo_ket_red PF00248.16 KZN83727.1 - 3.5e-49 167.1 0.0 4.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_6 PF01341.12 KZN83729.1 - 9.1e-110 366.7 4.5 1.1e-109 366.5 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CK_II_beta PF01214.13 KZN83730.1 - 6.8e-72 240.8 0.1 1.1e-71 240.1 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF805 PF05656.9 KZN83730.1 - 3.8 7.3 5.7 22 4.9 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Abhydrolase_5 PF12695.2 KZN83731.1 - 3.4e-08 33.3 0.0 1.5e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN83731.1 - 1.8e-07 31.2 2.8 3.2e-07 30.4 2.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN83731.1 - 0.00052 19.6 0.1 0.007 15.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KZN83731.1 - 0.0081 15.7 0.3 0.036 13.6 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 KZN83731.1 - 0.049 12.9 0.1 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) JAB PF01398.16 KZN83732.1 - 5.4e-09 35.7 0.2 6.1e-08 32.4 0.2 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_XkdX PF09693.5 KZN83732.1 - 0.076 12.5 0.6 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Lactamase_B PF00753.22 KZN83734.1 - 9.3e-23 80.8 1.7 1.4e-22 80.3 1.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN83734.1 - 0.0004 19.9 0.3 0.00061 19.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.9 KZN83735.1 - 8.7e-06 25.7 0.0 7.9e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN83735.1 - 0.0033 17.2 0.0 0.0093 15.7 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KZN83735.1 - 0.013 14.4 0.2 0.023 13.6 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN83735.1 - 0.014 15.4 0.1 0.041 13.9 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 KZN83735.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Mito_carr PF00153.22 KZN83736.1 - 1.5e-42 143.2 2.2 7.9e-17 60.7 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Dynamin_N PF00350.18 KZN83739.1 - 3.6e-26 91.9 1.1 2.6e-14 53.4 0.1 2.8 2 1 1 3 3 3 2 Dynamin family Dynamin_M PF01031.15 KZN83739.1 - 1.3e-11 43.7 0.0 7.7e-11 41.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KZN83739.1 - 1.2e-05 25.1 0.0 4.4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KZN83739.1 - 0.0019 18.0 2.4 0.0083 15.9 0.0 3.1 3 1 0 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 KZN83739.1 - 0.0029 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KZN83739.1 - 0.013 14.6 0.2 0.19 10.7 0.0 2.7 2 1 0 2 2 2 0 AIG1 family FeoB_N PF02421.13 KZN83739.1 - 0.018 14.2 0.6 2.6 7.3 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Ras PF00071.17 KZN83739.1 - 0.026 13.8 0.0 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.1 KZN83739.1 - 0.064 13.2 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Spo0A_C PF08769.6 KZN83739.1 - 0.12 12.2 0.4 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF3134 PF11332.3 KZN83740.1 - 0.02 15.0 0.1 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Ins_P5_2-kin PF06090.7 KZN83740.1 - 0.1 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Trypan_PARP PF05887.6 KZN83741.1 - 0.00016 21.5 31.0 0.00016 21.5 21.5 14.8 8 3 9 17 17 17 6 Procyclic acidic repetitive protein (PARP) HMG_box_2 PF09011.5 KZN83742.1 - 1.2e-05 25.5 7.4 4.7e-05 23.6 0.2 3.3 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 KZN83742.1 - 0.0017 18.5 1.2 0.0017 18.5 0.9 3.2 2 2 0 2 2 2 1 HMG (high mobility group) box HMG_box_5 PF14887.1 KZN83742.1 - 0.0038 16.9 0.3 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DEAD PF00270.24 KZN83743.1 - 3.5e-43 147.0 0.0 3e-42 143.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN83743.1 - 7e-25 86.7 0.0 2.4e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KZN83743.1 - 0.0055 15.5 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Metaviral_G PF09595.5 KZN83744.1 - 0.19 11.3 4.5 0.23 11.1 3.1 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein zf-C2H2 PF00096.21 KZN83745.1 - 3.2e-21 74.3 41.6 9.5e-06 25.6 3.0 8.3 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN83745.1 - 5.8e-18 64.2 37.2 2.1e-07 30.8 1.6 7.7 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN83745.1 - 6e-13 48.1 44.1 0.0016 18.6 1.2 8.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN83745.1 - 8.2e-06 25.8 20.1 0.0029 17.7 0.2 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN83745.1 - 0.00033 20.7 24.5 0.004 17.2 0.1 6.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN83745.1 - 0.0089 15.8 1.3 0.0089 15.8 0.9 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger DUF1690 PF07956.6 KZN83746.1 - 0.08 12.9 1.7 0.089 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) PapG_C PF03628.8 KZN83746.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PapG chaperone-binding domain Podoplanin PF05808.6 KZN83747.1 - 5.7e-06 25.9 0.6 9.1e-06 25.3 0.4 1.2 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 KZN83747.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KZN83747.1 - 0.0052 16.0 0.9 0.0052 16.0 0.6 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KZN83747.1 - 0.0067 16.0 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 KZN83747.1 - 0.012 13.9 0.2 0.016 13.4 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KZN83747.1 - 0.022 14.4 0.4 0.051 13.2 0.0 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 Plasmodium_Vir PF05795.6 KZN83747.1 - 0.032 13.4 0.2 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Phage_Coat_B PF05356.6 KZN83747.1 - 0.042 13.5 2.9 0.086 12.5 2.0 1.6 1 1 0 1 1 1 0 Phage Coat protein B Rifin_STEVOR PF02009.11 KZN83747.1 - 0.044 13.4 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family VSP PF03302.8 KZN83747.1 - 0.06 11.9 8.1 0.18 10.4 5.6 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein TMEM154 PF15102.1 KZN83747.1 - 0.071 12.8 0.9 0.11 12.2 0.6 1.4 1 1 0 1 1 1 0 TMEM154 protein family DUF4366 PF14283.1 KZN83747.1 - 0.097 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1517 PF07466.6 KZN83747.1 - 0.11 11.5 1.8 0.15 11.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Hamartin PF04388.7 KZN83747.1 - 2.3 6.7 8.1 2.8 6.5 5.6 1.1 1 0 0 1 1 1 0 Hamartin protein polyprenyl_synt PF00348.12 KZN83748.1 - 9.8e-13 47.5 0.0 1e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 KZN83749.1 - 1.4e-07 30.9 0.0 2.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KZN83749.1 - 0.059 13.0 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KZN83751.1 - 8.8e-09 34.8 0.0 5.8e-08 32.1 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83751.1 - 4.8e-06 25.8 0.0 7.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN83751.1 - 4.6e-05 23.2 0.1 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN83751.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase CrtC PF07143.6 KZN83752.1 - 1.6e-10 40.7 0.5 3.8e-10 39.5 0.4 1.5 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Sulfotransfer_3 PF13469.1 KZN83753.1 - 0.047 14.6 0.7 0.25 12.2 0.5 2.1 1 1 0 1 1 1 0 Sulfotransferase family DUF2985 PF11204.3 KZN83755.1 - 2.5e-12 46.3 0.0 5.7e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sugar_tr PF00083.19 KZN83759.1 - 1.8e-89 300.3 26.2 2.1e-89 300.1 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83759.1 - 1.2e-31 109.7 58.4 2.5e-29 102.1 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KZN83759.1 - 2.9e-07 28.9 6.1 0.0018 16.4 0.0 2.7 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KZN83759.1 - 0.00029 20.5 1.1 0.88 9.3 0.0 2.9 3 0 0 3 3 3 2 MFS_1 like family ADH_zinc_N PF00107.21 KZN83761.1 - 6.2e-07 29.0 0.0 9.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.19 KZN83762.1 - 9.8e-80 268.3 20.3 1.2e-79 268.0 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83762.1 - 1e-22 80.3 23.4 1e-22 80.3 16.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN83763.1 - 4.1e-12 45.5 0.4 1.2e-11 44.0 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN83763.1 - 2.4e-09 36.9 10.4 8.2e-05 22.7 0.8 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN83763.1 - 1.9e-07 30.9 2.3 1.9e-07 30.9 1.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN83763.1 - 1.8e-05 24.7 16.9 5.8e-05 23.1 1.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 KZN83763.1 - 0.00012 21.8 11.6 0.00012 21.8 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 KZN83763.1 - 0.00035 20.6 0.5 0.00035 20.6 0.3 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN83763.1 - 0.019 14.8 1.3 0.019 14.8 0.9 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN83763.1 - 0.064 13.4 5.9 0.53 10.5 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Condensation PF00668.15 KZN83763.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Condensation domain RRN7 PF11781.3 KZN83763.1 - 8.5 5.9 9.4 5.5 6.5 0.1 3.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Glyco_hydro_31 PF01055.21 KZN83764.1 - 1.4e-131 439.3 6.3 1.7e-131 439.1 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN83764.1 - 0.00023 20.9 1.6 0.00054 19.7 0.1 2.5 3 1 0 3 3 3 1 Galactose mutarotase-like Glyco_hydro_39 PF01229.12 KZN83766.1 - 0.0024 16.3 0.1 0.0033 15.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Acetyltransf_3 PF13302.1 KZN83769.1 - 2.7e-17 63.2 0.0 3.1e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN83769.1 - 2.1e-05 24.4 0.0 6.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family adh_short PF00106.20 KZN83770.1 - 1.3e-26 93.5 0.0 2.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN83770.1 - 1.5e-19 70.7 0.1 3.4e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN83770.1 - 7.2e-14 51.8 0.1 3.6e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN83770.1 - 9e-06 25.2 0.0 4.2e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.19 KZN83771.1 - 2e-27 96.1 0.0 3.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Lactamase_B PF00753.22 KZN83772.1 - 1.2e-09 38.0 0.2 1.8e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN83772.1 - 1e-05 25.1 0.1 1.5e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EZH2_WD-Binding PF11616.3 KZN83773.1 - 0.55 10.1 6.0 10 6.0 0.3 2.7 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Pkinase PF00069.20 KZN83774.1 - 6.5e-37 127.0 0.0 1.8e-36 125.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83774.1 - 1.3e-18 67.0 0.0 2.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KZN83774.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 FHA domain YrbL-PhoP_reg PF10707.4 KZN83774.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UPF0261 PF06792.6 KZN83775.1 - 1.3e-147 491.4 1.3 1.5e-147 491.2 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) AdoHcyase PF05221.12 KZN83776.1 - 2.5e-136 452.9 0.0 2.8e-136 452.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KZN83776.1 - 5.5e-81 270.1 2.9 9.6e-81 269.3 2.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN83776.1 - 3.6e-06 26.2 0.1 6.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KZN83776.1 - 0.0022 17.5 0.2 0.005 16.4 0.2 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KZN83776.1 - 0.0028 17.0 0.4 0.005 16.2 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KZN83776.1 - 0.0033 17.4 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.14 KZN83776.1 - 0.039 12.6 0.2 0.21 10.1 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase adh_short PF00106.20 KZN83776.1 - 0.079 12.8 1.2 8.4 6.2 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase F420_oxidored PF03807.12 KZN83776.1 - 0.081 13.3 0.2 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4448 PF14610.1 KZN83776.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RPM2 PF08579.6 KZN83776.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) 3HCDH_N PF02737.13 KZN83776.1 - 0.16 11.6 0.9 0.3 10.7 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HMG-CoA_red PF00368.13 KZN83778.1 - 2.4e-99 332.5 0.0 2.8e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Acyl-CoA_dh_M PF02770.14 KZN83779.1 - 0.0042 16.5 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RVT_2 PF07727.9 KZN83781.1 - 1.5e-28 99.4 0.0 2.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KZN83781.1 - 2.1e-11 44.0 0.0 4.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CDK5_activator PF03261.10 KZN83781.1 - 1.8 7.8 6.7 4.4 6.5 4.6 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein ERM PF00769.14 KZN83781.1 - 6.1 6.2 14.0 0.3 10.5 5.2 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family UBN2_3 PF14244.1 KZN83782.1 - 0.00055 19.5 1.0 0.00083 18.9 0.2 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF2201_N PF13203.1 KZN83782.1 - 0.021 13.9 2.4 0.039 13.1 1.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2763 PF10961.3 KZN83782.1 - 3.8 7.9 7.7 11 6.4 5.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Acyl-CoA_dh_1 PF00441.19 KZN83783.1 - 2.2e-05 24.6 0.2 5.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 KZN83783.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA oxidase zf-C2H2_4 PF13894.1 KZN83784.1 - 1.5e-08 34.3 8.7 1.2e-05 25.3 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN83784.1 - 3.2e-08 33.4 7.9 3.1e-06 27.1 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN83784.1 - 1.5e-05 25.0 0.6 1.5e-05 25.0 0.4 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-Di19 PF05605.7 KZN83784.1 - 0.00046 20.2 4.1 0.0011 19.1 2.8 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KZN83784.1 - 0.00081 19.5 7.7 0.0017 18.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 KZN83784.1 - 0.0039 16.6 0.3 0.006 16.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 KZN83784.1 - 0.0056 16.7 0.4 0.0056 16.7 0.3 1.9 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.6 KZN83784.1 - 0.026 14.7 0.2 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) GnHR_trans PF12369.3 KZN83784.1 - 0.038 14.4 1.5 0.24 11.8 0.1 2.4 3 0 0 3 3 2 0 Gonadotropin hormone receptor transmembrane region zf-C2H2_2 PF12756.2 KZN83784.1 - 0.12 12.5 0.9 0.2 11.7 0.6 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PRP21_like_P PF12230.3 KZN83784.1 - 0.19 11.2 1.1 0.26 10.7 0.8 1.4 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-BED PF02892.10 KZN83784.1 - 0.41 10.4 5.0 0.86 9.4 3.5 1.5 1 0 0 1 1 1 0 BED zinc finger Kelch_6 PF13964.1 KZN83787.1 - 0.0007 19.6 2.7 1.6 9.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KZN83787.1 - 0.024 14.8 0.1 0.024 14.8 0.0 5.3 6 1 1 7 7 7 0 Galactose oxidase, central domain TPR_14 PF13428.1 KZN83788.1 - 3.9e-19 67.4 20.3 0.00066 20.0 0.1 11.0 8 3 5 13 13 11 4 Tetratricopeptide repeat HAT PF02184.11 KZN83788.1 - 2e-18 65.7 78.4 2.3e-14 52.8 3.5 13.2 15 0 0 15 15 15 4 HAT (Half-A-TPR) repeat Suf PF05843.9 KZN83788.1 - 4.7e-13 49.5 18.7 0.0012 18.6 0.1 6.0 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KZN83788.1 - 1e-11 45.0 13.4 1.1e-05 25.6 0.0 6.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN83788.1 - 8.5e-11 42.2 21.5 0.012 16.2 0.0 7.6 10 1 2 12 12 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN83788.1 - 1.1e-09 37.7 2.1 0.52 10.0 0.0 6.2 5 1 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 KZN83788.1 - 3.4e-08 33.0 1.9 0.21 11.8 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN83788.1 - 2e-05 24.4 12.6 0.5 10.3 0.0 7.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 KZN83788.1 - 4.3e-05 22.7 18.1 0.41 9.6 0.1 6.1 1 1 4 6 6 6 5 Tetratricopeptide repeat NRDE-2 PF08424.5 KZN83788.1 - 0.00017 20.5 26.9 0.027 13.3 6.8 5.1 4 3 0 4 4 4 3 NRDE-2, necessary for RNA interference TPR_2 PF07719.12 KZN83788.1 - 0.00098 18.8 19.3 0.17 11.9 0.0 7.8 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN83788.1 - 0.0025 17.3 2.2 7.2 6.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN83788.1 - 0.0087 15.7 11.8 5.4 7.0 0.0 6.2 8 0 0 8 8 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KZN83788.1 - 0.017 14.8 1.4 0.017 14.8 1.0 6.8 5 2 2 7 7 6 0 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 KZN83788.1 - 0.049 13.5 5.5 15 5.5 0.7 5.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KZN83788.1 - 0.17 12.3 17.1 13 6.5 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Prp31_C PF09785.4 KZN83789.1 - 6e-43 146.2 0.2 1.1e-42 145.3 0.1 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KZN83789.1 - 2e-36 124.5 0.1 3.2e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KZN83789.1 - 1.2e-14 53.8 0.0 2.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain DUF3571 PF12095.3 KZN83789.1 - 0.12 12.5 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) MFS_1 PF07690.11 KZN83791.1 - 2.9e-30 105.1 52.7 1.5e-29 102.7 36.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83791.1 - 3e-07 29.4 17.8 3e-07 29.4 12.3 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter ketoacyl-synt PF00109.21 KZN83793.1 - 6.8e-66 222.3 0.0 1.8e-65 220.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KZN83793.1 - 2.2e-63 214.2 1.1 3.7e-63 213.4 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN83793.1 - 4.2e-53 180.7 0.1 8.3e-53 179.7 0.0 1.5 2 0 0 2 2 1 1 Acyl transferase domain KR PF08659.5 KZN83793.1 - 5.2e-51 172.8 0.2 3.7e-50 170.0 0.0 2.4 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 KZN83793.1 - 2.1e-40 138.3 4.4 1.2e-38 132.6 0.0 3.5 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN83793.1 - 1e-32 112.4 1.0 1.7e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN83793.1 - 6.6e-11 41.8 0.1 1.1e-09 37.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN83793.1 - 4.2e-09 37.3 0.0 6e-06 27.1 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Collagen PF01391.13 KZN83793.1 - 5.5e-08 32.2 14.1 1.3e-07 31.0 9.7 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PP-binding PF00550.20 KZN83793.1 - 1.5e-07 31.5 0.1 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 KZN83793.1 - 0.00025 20.7 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KZN83793.1 - 0.00035 19.6 0.3 0.001 18.1 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KZN83793.1 - 0.0012 18.4 0.6 0.006 16.2 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_12 PF08242.7 KZN83793.1 - 0.0088 16.5 0.0 0.16 12.4 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 KZN83793.1 - 0.011 15.8 0.5 0.3 11.0 0.1 2.9 3 0 0 3 3 3 0 NADH(P)-binding ACT PF01842.20 KZN83793.1 - 0.011 15.1 0.1 4.6 6.8 0.0 3.8 3 0 0 3 3 3 0 ACT domain Fungal_trans PF04082.13 KZN83794.1 - 2.7e-10 39.5 1.4 8.5e-10 37.9 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83794.1 - 0.0045 16.8 5.1 0.011 15.5 3.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KZN83795.1 - 3.9e-50 170.7 0.0 1.1e-33 116.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 PhyH PF05721.8 KZN83796.1 - 1.1e-07 32.1 0.0 4.9e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Med3 PF11593.3 KZN83797.1 - 1.1 8.4 6.7 1.3 8.1 4.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aldo_ket_red PF00248.16 KZN83798.1 - 1.4e-61 207.8 0.0 1.6e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 KZN83799.1 - 1e-06 28.6 9.4 1.5e-06 28.1 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN83799.1 - 2.3e-05 24.4 9.7 9.4e-05 22.4 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN83799.1 - 9.8e-05 22.4 0.7 9.8e-05 22.4 0.5 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN83799.1 - 0.0018 18.1 0.1 0.33 10.9 0.0 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN83799.1 - 0.041 14.0 5.4 0.14 12.3 0.3 3.0 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN83799.1 - 0.18 12.0 1.8 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SNF2_N PF00176.18 KZN83800.1 - 1.4e-64 217.8 0.1 2.3e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KZN83800.1 - 8.6e-21 73.3 9.7 1.3e-14 53.5 0.2 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KZN83800.1 - 2.6e-13 49.6 0.0 8.7e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KZN83800.1 - 1.4e-11 44.5 0.1 5.1e-11 42.6 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ABC_tran PF00005.22 KZN83801.1 - 1.1e-34 119.6 0.0 1.9e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KZN83801.1 - 2e-13 50.9 2.4 0.069 13.1 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KZN83801.1 - 5.8e-11 42.0 1.9 0.0019 17.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KZN83801.1 - 2.8e-06 28.1 0.6 0.099 13.4 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KZN83801.1 - 2.9e-06 26.5 0.0 1.5 7.7 0.0 4.3 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 KZN83801.1 - 1e-05 25.7 0.1 0.0069 16.5 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KZN83801.1 - 4.7e-05 22.8 0.3 0.074 12.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN83801.1 - 6.4e-05 23.1 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 KZN83801.1 - 7.8e-05 22.1 2.5 7.8e-05 22.1 1.7 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain DUF258 PF03193.11 KZN83801.1 - 8.4e-05 21.8 0.0 0.31 10.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KZN83801.1 - 9e-05 22.3 0.0 0.007 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KZN83801.1 - 9.4e-05 22.1 5.4 0.00017 21.3 3.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain UPF0079 PF02367.12 KZN83801.1 - 0.00012 21.6 0.7 0.00097 18.7 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KZN83801.1 - 0.00036 20.2 1.6 0.03 14.0 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KZN83801.1 - 0.00041 20.6 3.6 0.34 11.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 KZN83801.1 - 0.00077 19.6 0.1 0.28 11.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KZN83801.1 - 0.00087 18.9 1.9 0.056 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 KZN83801.1 - 0.0011 19.3 0.0 0.072 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 KZN83801.1 - 0.0015 18.0 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 KZN83801.1 - 0.0025 17.2 0.2 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN83801.1 - 0.0027 17.7 0.1 1.8 8.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KZN83801.1 - 0.0045 15.7 0.0 0.053 12.2 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RLI PF04068.10 KZN83801.1 - 0.0066 16.0 0.3 0.0066 16.0 0.2 2.3 3 0 0 3 3 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4_6 PF12837.2 KZN83801.1 - 0.0099 15.7 2.1 0.0099 15.7 1.5 1.9 2 0 0 2 2 1 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 KZN83801.1 - 0.011 15.0 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.17 KZN83801.1 - 0.011 15.1 3.7 0.13 11.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_10 PF13237.1 KZN83801.1 - 0.017 14.9 1.6 0.017 14.9 1.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Miro PF08477.8 KZN83801.1 - 0.02 15.3 0.1 1.2 9.6 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein Fer4_16 PF13484.1 KZN83801.1 - 0.021 15.5 1.8 0.049 14.3 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain SbcCD_C PF13558.1 KZN83801.1 - 0.024 14.5 0.1 11 5.9 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KZN83801.1 - 0.03 14.0 0.2 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_7 PF12838.2 KZN83801.1 - 0.033 14.5 6.6 0.097 13.0 4.7 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF815 PF05673.8 KZN83801.1 - 0.037 12.9 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 KZN83801.1 - 0.05 13.1 0.3 1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KZN83801.1 - 0.08 12.6 1.8 2.9 7.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_8 PF13183.1 KZN83801.1 - 0.093 12.7 6.4 0.33 11.0 1.1 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 KZN83801.1 - 0.094 12.9 8.2 0.062 13.5 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 KZN83801.1 - 0.099 11.4 0.2 8 5.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KZN83801.1 - 0.13 12.2 0.2 8.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KZN83801.1 - 0.14 11.6 2.1 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KZN83801.1 - 0.15 11.9 1.2 8.8 6.2 0.0 2.9 2 2 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 KZN83801.1 - 0.16 12.2 3.8 0.18 12.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 KZN83801.1 - 0.18 11.2 2.4 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 KZN83801.1 - 0.18 10.5 0.3 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_13 PF13166.1 KZN83801.1 - 0.29 9.5 0.0 0.29 9.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Fer4_18 PF13746.1 KZN83801.1 - 0.8 10.1 7.7 0.44 11.0 0.6 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 KZN83801.1 - 9.7 7.0 11.4 0.82 10.3 3.8 2.2 2 0 0 2 2 1 0 4Fe-4S binding domain Strep_67kDa_ant PF06100.6 KZN83803.1 - 2.1e-80 270.5 0.0 2.6e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family FF PF01846.14 KZN83804.1 - 6.5e-56 186.0 20.3 1.5e-15 56.8 0.9 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.21 KZN83804.1 - 1.6e-18 66.1 10.6 6.2e-09 35.5 3.1 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 KZN83805.1 - 2.2e-94 316.2 0.1 2.7e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 KZN83806.1 - 9.1e-22 76.4 0.1 9.1e-22 76.4 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 KZN83807.1 - 1.9e-149 497.4 0.5 2.2e-149 497.2 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.3 KZN83807.1 - 0.081 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.8 KZN83808.1 - 6.3e-25 86.7 15.2 8.4e-25 86.3 10.6 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.4 KZN83809.1 - 4.3e-157 523.4 0.1 6e-157 522.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Pneumo_att_G PF05539.6 KZN83809.1 - 0.084 12.2 1.8 0.17 11.1 1.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GXWXG PF14231.1 KZN83809.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 GXWXG protein MFS_1 PF07690.11 KZN83810.1 - 8.4e-40 136.5 58.9 7e-39 133.5 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 KZN83810.1 - 0.00082 19.4 2.0 0.37 10.9 0.3 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2583) AMP-binding PF00501.23 KZN83811.1 - 0 1021.2 0.0 8.2e-87 291.2 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.15 KZN83811.1 - 6.8e-246 813.1 0.0 1e-47 162.4 0.0 9.1 9 1 0 9 9 9 7 Condensation domain PP-binding PF00550.20 KZN83811.1 - 1.6e-47 159.6 6.1 4e-10 39.8 0.1 6.1 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN83811.1 - 2.9e-15 56.9 1.2 0.0028 18.5 0.0 5.4 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.10 KZN83811.1 - 0.00078 18.0 0.0 1.1 7.5 0.0 3.0 3 0 0 3 3 3 2 Transferase family DUF3409 PF11889.3 KZN83811.1 - 2.9 7.6 0.8 6.3 6.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) Cwf_Cwc_15 PF04889.7 KZN83811.1 - 4.6 6.8 0.8 8.3 6.0 0.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ABC_tran PF00005.22 KZN83812.1 - 7.6e-50 168.7 0.0 1.7e-26 93.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN83812.1 - 5.2e-32 111.3 29.5 2.2e-21 76.4 8.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KZN83812.1 - 1e-10 42.0 2.1 0.00078 19.4 0.0 4.3 4 1 1 5 5 4 2 AAA domain SMC_N PF02463.14 KZN83812.1 - 2.1e-09 36.9 4.6 0.007 15.6 0.1 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN83812.1 - 9.8e-09 35.4 3.3 2.5e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 KZN83812.1 - 1.4e-07 31.1 0.1 0.00058 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN83812.1 - 6.3e-07 28.8 0.8 0.0005 19.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KZN83812.1 - 3.2e-06 26.4 0.2 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN83812.1 - 6.4e-06 26.3 2.7 0.016 15.3 0.0 3.6 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 KZN83812.1 - 4.3e-05 23.9 0.6 0.072 13.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KZN83812.1 - 5.3e-05 22.2 0.1 0.014 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 KZN83812.1 - 6.4e-05 23.1 0.2 0.082 13.1 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KZN83812.1 - 0.00016 22.1 1.4 0.4 11.1 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 KZN83812.1 - 0.00021 21.0 0.0 0.011 15.4 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 KZN83812.1 - 0.00043 19.8 0.1 0.48 9.8 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KZN83812.1 - 0.00044 20.1 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 KZN83812.1 - 0.00049 20.2 0.1 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KZN83812.1 - 0.00082 19.2 0.1 0.077 12.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KZN83812.1 - 0.00092 18.7 2.6 0.23 10.8 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 KZN83812.1 - 0.0011 19.8 2.5 0.13 13.0 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KZN83812.1 - 0.0011 18.5 0.3 1.2 8.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KZN83812.1 - 0.0034 17.0 0.3 0.25 10.9 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.7 KZN83812.1 - 0.0038 16.3 0.3 1.2 8.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 KZN83812.1 - 0.0074 15.9 1.2 3.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KZN83812.1 - 0.0091 14.8 0.5 3.3 6.3 0.1 2.4 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 KZN83812.1 - 0.021 14.4 0.5 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KZN83812.1 - 0.023 14.2 0.1 1.6 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 KZN83812.1 - 0.026 13.9 0.2 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KZN83812.1 - 0.031 14.0 2.2 0.69 9.6 0.1 2.9 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KZN83812.1 - 0.034 14.4 2.2 1 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KZN83812.1 - 0.034 13.8 1.4 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 KZN83812.1 - 0.036 13.9 0.6 0.52 10.2 0.0 2.9 4 0 0 4 4 2 0 AAA domain Guanylate_kin PF00625.16 KZN83812.1 - 0.041 13.3 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase cobW PF02492.14 KZN83812.1 - 0.056 12.8 1.7 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 KZN83812.1 - 0.057 13.3 0.0 12 5.8 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 KZN83812.1 - 0.061 12.2 0.3 1.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KZN83812.1 - 0.068 12.0 1.0 8.4 5.1 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain Dynamin_N PF00350.18 KZN83812.1 - 0.083 12.6 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.7 KZN83812.1 - 0.089 12.0 0.4 8.1 5.6 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 KZN83812.1 - 0.099 12.1 1.2 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 KZN83812.1 - 0.13 10.8 1.5 0.2 10.2 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_11 PF13086.1 KZN83812.1 - 0.16 11.4 0.0 19 4.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KZN83812.1 - 0.17 10.8 0.0 0.39 9.7 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KZN83812.1 - 0.2 11.0 3.3 6.3 6.1 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Rad17 PF03215.10 KZN83812.1 - 0.24 10.0 0.2 0.39 9.3 0.2 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 KZN83812.1 - 0.39 10.2 1.7 5.3 6.5 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KZN83812.1 - 0.47 10.0 0.8 12 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KZN83812.1 - 0.58 10.1 2.8 0.25 11.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.12 KZN83812.1 - 0.64 9.7 2.3 3.1 7.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Nup160 PF11715.3 KZN83813.1 - 4.3e-157 523.5 1.5 7.2e-157 522.8 1.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 KZN83814.1 - 7.4e-138 457.6 0.0 9.1e-138 457.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KZN83814.1 - 4e-14 52.4 0.0 5.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KZN83814.1 - 9e-09 35.3 0.3 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KZN83814.1 - 1.7e-08 33.9 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KZN83814.1 - 3e-05 23.2 0.5 7.3e-05 21.9 0.1 1.9 2 1 0 2 2 2 1 KaiC DnaB_C PF03796.10 KZN83814.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KZN83814.1 - 0.076 11.8 0.2 0.22 10.3 0.1 1.7 2 0 0 2 2 2 0 PAXNEB protein FAD_binding_4 PF01565.18 KZN83815.1 - 3.2e-15 55.8 0.1 4.9e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 KZN83815.1 - 3.7e-05 23.4 2.7 8.4e-05 22.2 0.2 2.2 2 1 0 2 2 2 1 D-arabinono-1,4-lactone oxidase GMC_oxred_N PF00732.14 KZN83816.1 - 7e-82 274.9 0.0 8.8e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN83816.1 - 0.0013 18.6 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN83816.1 - 0.0024 16.8 0.8 0.0046 15.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN83816.1 - 0.0077 15.1 0.1 0.015 14.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KZN83816.1 - 0.032 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KZN83816.1 - 0.057 12.5 0.5 0.16 11.0 0.0 1.9 3 0 0 3 3 3 0 Thi4 family Fungal_trans PF04082.13 KZN83817.1 - 4.3e-06 25.8 0.2 8.4e-06 24.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prefoldin PF02996.12 KZN83818.1 - 7.1e-25 86.9 0.2 9.3e-25 86.6 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KZN83818.1 - 0.0022 17.7 1.5 0.055 13.2 0.4 2.0 2 0 0 2 2 2 2 Prefoldin subunit Requiem_N PF14051.1 KZN83819.1 - 0.33 10.8 3.0 0.39 10.6 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of DPF2/REQ. AAA PF00004.24 KZN83820.1 - 4.6e-14 52.7 0.0 8.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN83820.1 - 2.1e-09 37.6 0.1 9.4e-09 35.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN83820.1 - 1.8e-08 34.6 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN83820.1 - 7.2e-06 26.8 0.0 0.00075 20.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain BAH PF01426.13 KZN83820.1 - 2.3e-05 24.1 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.1 KZN83820.1 - 0.00073 19.5 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN83820.1 - 0.00086 19.0 1.3 0.0027 17.4 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KZN83820.1 - 0.0018 17.3 0.0 0.0036 16.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.1 KZN83820.1 - 0.0052 15.5 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN83820.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KZN83820.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KZN83820.1 - 0.015 15.6 0.0 0.057 13.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KZN83820.1 - 0.026 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 KZN83820.1 - 0.031 13.2 0.4 0.071 12.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase Arch_ATPase PF01637.13 KZN83820.1 - 0.057 13.1 0.0 0.47 10.1 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KZN83820.1 - 0.096 11.6 0.0 0.46 9.4 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KZN83820.1 - 0.12 12.6 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Kinesin PF00225.18 KZN83820.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain WD40 PF00400.27 KZN83821.1 - 6e-56 184.4 11.8 6.8e-10 38.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KZN83821.1 - 0.0045 15.1 5.3 8.2 4.4 0.0 4.6 1 1 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KZN83821.1 - 0.039 13.4 0.3 2.8 7.3 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 KZN83821.1 - 0.18 10.5 0.0 6.4 5.3 0.0 3.0 1 1 1 2 2 2 0 Nup133 N terminal like Ank_2 PF12796.2 KZN83822.1 - 5.6e-46 154.7 0.1 2.6e-18 66.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN83822.1 - 1.1e-34 117.6 0.1 6.6e-10 38.9 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KZN83822.1 - 2.2e-30 102.9 0.1 0.00029 20.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KZN83822.1 - 3.5e-29 100.6 0.1 1.3e-09 38.2 0.0 4.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83822.1 - 6.9e-25 84.6 0.1 0.029 14.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat LHH PF14411.1 KZN83822.1 - 0.024 14.8 0.0 0.069 13.3 0.0 1.8 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Shal-type PF11601.3 KZN83822.1 - 0.03 13.8 0.2 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels Pyr_redox_3 PF13738.1 KZN83823.1 - 1.6e-22 80.5 0.0 4.1e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN83823.1 - 9.4e-16 57.0 0.0 4.1e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN83823.1 - 1.9e-10 40.2 0.4 4.7e-08 32.3 0.0 2.6 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KZN83823.1 - 0.028 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN83823.1 - 0.046 13.5 0.0 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4219 PF13961.1 KZN83824.1 - 0.82 9.1 0.0 0.82 9.1 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4219) PTR2 PF00854.16 KZN83825.1 - 1e-27 96.9 12.3 5.1e-16 58.4 1.4 2.4 1 1 1 2 2 2 2 POT family ATP-grasp_4 PF13535.1 KZN83826.1 - 3.3e-22 79.1 0.0 1.3e-18 67.3 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KZN83826.1 - 3e-07 30.0 0.0 5.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 KZN83826.1 - 1.3e-05 24.5 0.0 0.00014 21.2 0.0 2.4 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KZN83826.1 - 0.00012 20.9 0.0 0.0026 16.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KZN83826.1 - 0.00047 20.0 0.0 0.0076 16.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KZN83826.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KZN83826.1 - 0.003 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 KZN83826.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Pyr_redox_3 PF13738.1 KZN83827.1 - 8.1e-20 71.7 0.1 1.6e-19 70.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN83827.1 - 2.7e-13 48.9 0.4 7.3e-13 47.5 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN83827.1 - 3.2e-10 39.8 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN83827.1 - 3.7e-07 29.3 0.0 3.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KZN83827.1 - 0.00051 19.0 0.1 0.039 12.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN83827.1 - 0.00056 19.7 0.5 0.038 13.7 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KZN83827.1 - 0.017 15.0 0.0 0.053 13.3 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KZN83827.1 - 0.02 13.1 0.1 0.35 9.0 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 KZN83827.1 - 0.041 12.9 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 KZN83827.1 - 0.37 9.7 0.9 0.72 8.8 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain HNH_2 PF13391.1 KZN83828.1 - 3.6e-16 58.6 0.0 7e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease His_Phos_2 PF00328.17 KZN83829.1 - 6.4e-13 48.7 0.0 2.5e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 KZN83830.1 - 8.3e-32 110.2 40.5 8.3e-32 110.2 28.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KZN83831.1 - 1.6e-59 201.4 4.0 2e-59 201.1 2.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83831.1 - 3.7e-08 33.1 10.4 6.2e-08 32.4 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_H_N PF03224.9 KZN83832.1 - 2.2e-80 270.0 0.0 3.3e-80 269.5 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KZN83832.1 - 7.7e-40 135.5 0.1 2.9e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.18 KZN83832.1 - 0.089 12.6 0.0 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TMF_TATA_bd PF12325.3 KZN83833.1 - 3.4e-43 146.2 12.1 3.4e-43 146.2 8.4 6.2 2 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KZN83833.1 - 4.4e-20 71.2 17.3 4.4e-20 71.2 12.0 9.7 5 4 5 10 10 10 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 KZN83833.1 - 0.56 10.5 31.3 0.13 12.5 1.0 6.4 7 1 1 8 8 8 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KZN83833.1 - 4.9 7.2 53.0 0.22 11.6 7.6 5.8 3 1 3 6 6 6 0 Fibrinogen alpha/beta chain family NADH-u_ox-rdase PF10785.4 KZN83835.1 - 1.6 9.0 6.6 6.9 6.9 0.2 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PrgI PF12666.2 KZN83835.1 - 4.9 7.3 6.1 3.9 7.6 1.9 2.3 1 1 1 2 2 2 0 PrgI family protein Filament PF00038.16 KZN83836.1 - 0.0001 21.8 5.4 0.0001 21.8 3.8 5.7 4 1 1 6 6 6 4 Intermediate filament protein Apq12 PF12716.2 KZN83837.1 - 1.9e-17 62.6 13.6 1.9e-17 62.6 9.4 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 KZN83838.1 - 2.6e-75 253.0 0.2 2.9e-75 252.8 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KZN83838.1 - 1.4e-05 25.8 0.0 6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KZN83838.1 - 0.00046 19.1 0.3 0.00099 18.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KZN83838.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KZN83838.1 - 0.00072 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN83838.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN83838.1 - 0.0026 17.9 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN83838.1 - 0.0026 17.7 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_31 PF13614.1 KZN83838.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KZN83838.1 - 0.0041 17.3 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KZN83838.1 - 0.0048 16.3 0.0 0.0092 15.4 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 KZN83838.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KZN83838.1 - 0.022 14.4 0.1 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KZN83838.1 - 0.025 14.0 0.2 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KZN83838.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 KZN83838.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KZN83838.1 - 0.041 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KZN83838.1 - 0.045 13.2 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KZN83838.1 - 0.051 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArsA_ATPase PF02374.10 KZN83838.1 - 0.052 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase GTP_EFTU PF00009.22 KZN83838.1 - 0.055 12.9 0.1 8.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.21 KZN83838.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KZN83838.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Gtr1_RagA PF04670.7 KZN83838.1 - 0.06 12.4 0.0 0.2 10.7 0.0 2.0 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Septin PF00735.13 KZN83838.1 - 0.074 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.9 KZN83838.1 - 0.088 11.7 0.0 0.2 10.5 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain RuvB_N PF05496.7 KZN83838.1 - 0.097 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 KZN83838.1 - 0.098 12.9 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 KZN83838.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein S-AdoMet_synt_C PF02773.11 KZN83839.1 - 6.5e-78 259.1 1.3 7.8e-77 255.6 0.2 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KZN83839.1 - 1.6e-45 153.9 0.0 2.8e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KZN83839.1 - 1.6e-42 143.7 0.7 2.7e-42 143.0 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.1 KZN83839.1 - 0.061 13.0 0.1 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF2312 PF10073.4 KZN83839.1 - 0.087 12.1 0.3 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) SLD3 PF08639.5 KZN83840.1 - 1.4e-146 489.0 7.9 1.4e-146 489.0 5.5 1.4 2 0 0 2 2 2 1 DNA replication regulator SLD3 DUF420 PF04238.7 KZN83841.1 - 0.0021 17.9 1.5 0.0021 17.9 1.1 2.2 4 0 0 4 4 4 1 Protein of unknown function (DUF420) DUF2910 PF11139.3 KZN83841.1 - 0.0039 16.3 0.7 0.0039 16.3 0.5 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2910) DUF3671 PF12420.3 KZN83841.1 - 1.6 8.7 11.3 4.5 7.2 1.7 2.6 1 1 1 2 2 2 0 Protein of unknown function SpoIIIAC PF06686.6 KZN83841.1 - 3.1 7.6 8.6 0.66 9.8 1.2 2.7 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family GFA PF04828.9 KZN83845.1 - 1e-21 76.6 1.3 1.9e-21 75.8 0.8 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 KZN83845.1 - 0.15 11.7 0.5 0.15 11.7 0.4 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Cys_rich_CWC PF14375.1 KZN83845.1 - 0.3 11.0 8.3 4.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC CRC_subunit PF08624.5 KZN83847.1 - 9.7e-53 177.8 0.0 1.4e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit F-box-like PF12937.2 KZN83848.1 - 0.0022 17.7 1.2 0.057 13.1 0.0 3.2 4 0 0 4 4 4 1 F-box-like His_Phos_1 PF00300.17 KZN83849.1 - 7e-12 45.7 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hydrolase_4 PF12146.3 KZN83849.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Homeobox PF00046.24 KZN83850.1 - 8.4e-17 60.5 2.5 2.3e-16 59.1 1.7 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KZN83850.1 - 8.4e-07 28.5 0.4 2.3e-06 27.1 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 KZN83851.1 - 5.1e-17 62.6 0.0 6.5e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN83851.1 - 7.5e-10 39.5 0.0 2.9e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN83851.1 - 6.8e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KZN83851.1 - 0.00087 19.5 0.0 0.0016 18.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_A4 PF01828.12 KZN83851.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase A4 family MMR_HSR1 PF01926.18 KZN83852.1 - 3.1e-23 81.9 0.2 6.3e-16 58.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 KZN83852.1 - 2.6e-22 78.5 17.4 2.6e-22 78.5 12.0 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase GTP_EFTU PF00009.22 KZN83852.1 - 1.1e-06 28.1 0.3 0.083 12.3 0.0 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KZN83852.1 - 2e-05 23.8 0.0 0.00025 20.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KZN83852.1 - 5.5e-05 23.0 9.3 0.16 11.8 0.2 4.5 3 2 1 4 4 4 2 Dynamin family DUF258 PF03193.11 KZN83852.1 - 0.0011 18.1 1.2 0.0014 17.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KZN83852.1 - 0.0019 18.7 2.4 0.42 11.1 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein ArgK PF03308.11 KZN83852.1 - 0.011 14.5 0.1 0.011 14.5 0.0 2.0 2 0 0 2 2 2 0 ArgK protein SAPS PF04499.10 KZN83852.1 - 0.081 11.5 1.2 0.098 11.2 0.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Arf PF00025.16 KZN83852.1 - 0.082 12.1 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.1 KZN83852.1 - 0.12 12.3 2.3 0.7 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KZN83852.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN83852.1 - 0.5 11.1 0.0 0.5 11.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain Nop14 PF04147.7 KZN83852.1 - 1.4 6.7 25.7 2.6 5.8 17.8 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 KZN83852.1 - 4.6 7.0 16.4 6.8 6.4 11.0 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CBFD_NFYB_HMF PF00808.18 KZN83853.1 - 1.9e-05 24.6 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.8 KZN83853.1 - 0.00062 19.7 12.5 0.001 19.0 8.7 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 KZN83853.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.14 KZN83853.1 - 8.5 6.8 20.7 0.34 11.3 8.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SIR2 PF02146.12 KZN83854.1 - 8.9e-29 100.4 0.0 2.8e-28 98.8 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 KZN83855.1 - 7.6e-192 639.1 0.0 9.4e-191 635.5 0.0 1.9 1 1 1 2 2 2 2 Mediator complex subunit 16 Ribosomal_L29 PF00831.18 KZN83856.1 - 5.8e-18 64.3 0.7 5.8e-18 64.3 0.5 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein CorA PF01544.13 KZN83856.1 - 0.043 12.8 3.1 0.052 12.5 2.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cortex-I_coil PF09304.5 KZN83856.1 - 0.42 10.6 8.4 0.14 12.2 2.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3585 PF12130.3 KZN83856.1 - 0.44 10.3 5.0 0.6 9.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Snapin_Pallidin PF14712.1 KZN83856.1 - 3.2 8.1 6.7 0.45 10.8 1.2 1.9 1 1 1 2 2 2 0 Snapin/Pallidin V-SNARE_C PF12352.3 KZN83857.1 - 5.5e-12 45.5 0.0 5.5e-12 45.5 0.0 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 KZN83857.1 - 0.011 14.2 4.8 0.015 13.8 3.3 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.8 KZN83857.1 - 0.019 14.6 1.3 1.5 8.6 0.0 3.1 3 1 0 3 3 3 0 Sec20 Syntaxin-6_N PF09177.6 KZN83857.1 - 0.14 12.5 4.5 0.14 12.5 1.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Surfac_D-trimer PF09006.6 KZN83857.1 - 0.17 11.5 0.7 6.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation APG6 PF04111.7 KZN83857.1 - 0.7 8.8 4.9 1.2 8.1 3.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-H PF05837.7 KZN83857.1 - 3.9 7.6 8.3 2.5 8.3 4.1 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CorA PF01544.13 KZN83857.1 - 5.8 5.8 9.0 15 4.4 6.3 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 KZN83857.1 - 6.5 6.3 14.9 15 5.0 10.4 1.6 1 1 0 1 1 1 0 IncA protein DUF802 PF05650.6 KZN83857.1 - 9.9 6.3 9.4 7.4 6.7 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF802) ATP-synt_10 PF05176.9 KZN83858.1 - 2e-90 302.4 0.0 2.5e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Phosphodiest PF01663.17 KZN83860.1 - 1.2e-09 37.9 0.1 8.3e-09 35.2 0.0 1.9 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KZN83860.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KZN83860.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Sulfatase adh_short PF00106.20 KZN83861.1 - 1.2e-12 48.0 0.0 1.5e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN83861.1 - 0.0003 20.6 0.0 0.00039 20.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN83861.1 - 0.003 17.2 0.0 0.0035 17.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN83861.1 - 0.067 13.1 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 KZN83861.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein MFS_1 PF07690.11 KZN83862.1 - 1.8e-42 145.3 64.2 4.8e-42 143.9 42.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN83862.1 - 4e-14 51.7 30.0 2.5e-13 49.1 19.8 2.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN83862.1 - 9.3e-13 47.5 12.7 9.3e-13 47.5 8.8 3.6 3 1 0 3 3 3 1 Sugar (and other) transporter Kinocilin PF15033.1 KZN83862.1 - 0.38 10.2 0.0 0.38 10.2 0.0 3.5 4 0 0 4 4 4 0 Kinocilin protein Abhydrolase_6 PF12697.2 KZN83863.1 - 9.2e-14 51.8 0.3 1.1e-13 51.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN83863.1 - 1.1e-10 41.4 0.3 7.2e-10 38.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KZN83863.1 - 6e-07 28.2 0.1 8.8e-07 27.7 0.1 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KZN83863.1 - 6.5e-06 25.5 0.0 0.0017 17.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 KZN83863.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KZN83863.1 - 0.00063 19.2 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KZN83863.1 - 0.0011 18.2 0.0 0.071 12.3 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family HTH_23 PF13384.1 KZN83863.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Esterase PF00756.15 KZN83863.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3990 PF13151.1 KZN83864.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Herpes_IE68 PF02479.11 KZN83864.1 - 0.098 11.8 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus immediate early protein KR PF08659.5 KZN83865.1 - 9.1e-51 172.0 0.2 2e-50 170.9 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KZN83865.1 - 1e-35 123.1 0.1 8.5e-35 120.1 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KZN83865.1 - 2.2e-16 59.5 0.0 5.5e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN83865.1 - 1.3e-12 48.6 0.0 4.8e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN83865.1 - 4.1e-05 23.3 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PS-DH PF14765.1 KZN83865.1 - 0.00017 20.8 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Fungal_trans_2 PF11951.3 KZN83866.1 - 0.0024 16.5 0.1 0.0046 15.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 KZN83867.1 - 8.6e-39 133.3 1.4 1.1e-38 132.9 1.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DNA_pol_B_palm PF14792.1 KZN83868.1 - 6.6e-32 109.8 0.0 1.4e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KZN83868.1 - 1.7e-21 75.6 0.0 3.3e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KZN83868.1 - 1.3e-18 66.9 0.5 2.8e-18 65.8 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KZN83868.1 - 4.6e-16 58.0 0.3 1.4e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.21 KZN83868.1 - 0.0052 16.9 0.0 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 KZN83868.1 - 0.035 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH PF00633.18 KZN83868.1 - 0.059 13.0 0.2 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif PTCB-BRCT PF12738.2 KZN83868.1 - 0.14 12.0 0.0 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain Zn_clus PF00172.13 KZN83869.1 - 0.0033 17.3 4.7 0.0083 16.0 3.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.10 KZN83869.1 - 0.0045 16.7 0.3 0.0045 16.7 0.2 1.8 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.1 KZN83869.1 - 0.026 14.4 2.5 0.24 11.3 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CPL PF08144.6 KZN83871.1 - 3.7e-16 59.2 0.1 2.4e-15 56.6 0.0 2.5 2 0 0 2 2 2 1 CPL (NUC119) domain Daxx PF03344.10 KZN83871.1 - 0.02 13.4 27.2 0.038 12.4 18.9 1.4 1 0 0 1 1 1 0 Daxx Family AA_permease PF00324.16 KZN83874.1 - 1e-132 442.8 44.5 1.3e-132 442.5 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN83874.1 - 2.6e-35 121.7 50.6 3.6e-35 121.3 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KZN83875.1 - 1.3e-16 60.2 58.4 1.1e-13 50.6 40.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN83875.1 - 3.3e-12 45.4 28.3 4.9e-12 44.8 19.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KZN83875.1 - 0.0026 17.6 1.4 0.017 15.0 1.0 2.4 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Arylsulfotran_2 PF14269.1 KZN83876.1 - 7.5e-119 396.3 4.0 9.1e-119 396.0 2.8 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Acetyltransf_1 PF00583.19 KZN83877.1 - 3.1e-11 43.1 0.5 7e-11 42.0 0.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN83877.1 - 3.2e-11 43.2 0.0 9.6e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN83877.1 - 1e-06 28.8 0.1 2.7e-06 27.5 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN83877.1 - 4.8e-05 23.2 0.1 0.00067 19.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN83877.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KZN83877.1 - 0.04 13.6 0.0 0.2 11.4 0.0 2.1 1 1 0 1 1 1 0 FR47-like protein Pyr_redox PF00070.22 KZN83878.1 - 2.7e-13 50.1 3.2 8.6e-12 45.2 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN83878.1 - 2.2e-09 37.6 0.0 0.00084 19.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN83878.1 - 1.2e-05 24.3 0.0 4.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN83878.1 - 1.4e-05 25.1 3.6 0.00074 19.4 0.5 3.2 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN83878.1 - 3.4e-05 22.9 2.3 0.099 11.5 0.4 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN83878.1 - 8.5e-05 21.6 0.3 0.0016 17.4 0.1 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KZN83878.1 - 0.00026 19.7 1.2 1.1 7.7 0.6 3.5 4 0 0 4 4 4 2 Tryptophan halogenase HI0933_like PF03486.9 KZN83878.1 - 0.011 14.2 1.1 0.17 10.3 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 KZN83878.1 - 0.034 13.1 1.0 1.4 7.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KZN83878.1 - 0.12 12.1 2.4 1 9.1 0.0 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KZN83878.1 - 0.64 9.0 4.7 5.7 5.8 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase ABC_membrane PF00664.18 KZN83879.1 - 2.3e-70 237.1 31.9 1.1e-42 146.3 7.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN83879.1 - 4e-66 221.5 0.0 1.8e-32 112.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN83879.1 - 1.1e-15 57.4 1.0 2.7e-05 23.4 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN83879.1 - 2.1e-09 37.7 0.0 0.024 14.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KZN83879.1 - 7.6e-09 35.8 2.1 0.00063 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KZN83879.1 - 1.2e-08 34.3 0.6 0.0019 17.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KZN83879.1 - 4.2e-07 30.8 0.0 0.066 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KZN83879.1 - 2.3e-06 26.5 0.4 0.0016 17.1 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 KZN83879.1 - 2.1e-05 24.6 0.5 0.52 10.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.1 KZN83879.1 - 3.1e-05 23.6 3.4 0.13 11.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 KZN83879.1 - 3.8e-05 23.1 0.2 0.12 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KZN83879.1 - 4.5e-05 22.6 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KZN83879.1 - 0.00019 21.2 0.2 1.2 9.0 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KZN83879.1 - 0.00022 21.1 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KZN83879.1 - 0.00033 20.3 0.2 0.21 11.2 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KZN83879.1 - 0.00047 19.3 0.1 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KZN83879.1 - 0.00076 19.8 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN83879.1 - 0.0012 19.1 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KZN83879.1 - 0.0058 16.0 0.6 3.1 7.1 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 KZN83879.1 - 0.007 16.1 0.0 1.7 8.4 0.0 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KZN83879.1 - 0.0078 16.0 0.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF3987 PF13148.1 KZN83879.1 - 0.01 14.4 0.0 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA PF00004.24 KZN83879.1 - 0.023 14.8 0.7 37 4.5 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KZN83879.1 - 0.055 13.1 0.2 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KZN83879.1 - 0.079 11.8 0.0 7.6 5.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 KZN83879.1 - 0.08 12.9 1.3 9.1 6.2 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KZN83879.1 - 0.088 12.7 0.0 27 4.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Acetyltransf_8 PF13523.1 KZN83880.1 - 1.1e-39 135.6 0.4 1.7e-39 135.1 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 KZN83881.1 - 6e-88 295.0 0.0 3.7e-85 285.8 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KZN83881.1 - 1.6e-64 217.6 0.0 5e-35 120.8 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KZN83881.1 - 3.8e-26 91.1 1.3 1.9e-12 47.2 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site zf-DHHC PF01529.15 KZN83884.1 - 0.86 8.9 2.8 6.3 6.1 1.8 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase ketoacyl-synt PF00109.21 KZN83885.1 - 2.4e-76 256.5 0.9 8.8e-76 254.7 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN83885.1 - 6.4e-57 192.1 0.0 1.5e-56 190.9 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KZN83885.1 - 1.1e-55 189.2 0.0 2.1e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KZN83885.1 - 3.8e-47 160.8 0.0 6.6e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KZN83885.1 - 2.6e-42 144.5 0.0 6.1e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN83885.1 - 3.4e-37 126.9 0.0 8.8e-37 125.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KZN83885.1 - 6.7e-06 26.2 0.1 2.9e-05 24.2 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN83885.1 - 0.0032 16.4 0.1 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 KZN83885.1 - 0.0056 16.3 0.6 0.021 14.4 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 KZN83885.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN83886.1 - 2.8e-11 43.0 0.1 7.5e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN83886.1 - 6.9e-05 22.5 0.3 0.00026 20.7 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN83886.1 - 0.0039 18.0 0.1 0.18 12.6 0.1 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF2436 PF10365.4 KZN83886.1 - 0.063 12.8 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2436) Cupin_2 PF07883.6 KZN83887.1 - 1.5e-20 72.4 0.3 2.6e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KZN83887.1 - 2.6e-17 61.9 1.9 1.7e-13 49.7 0.3 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KZN83887.1 - 9.5e-06 25.1 0.0 0.00039 19.8 0.0 2.4 2 1 0 2 2 2 1 Cupin AraC_binding PF02311.14 KZN83887.1 - 3.3e-05 23.5 0.1 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.3 KZN83887.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.5 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_6 PF12852.2 KZN83887.1 - 0.0099 15.5 0.0 2.2 7.8 0.0 2.3 1 1 1 2 2 2 2 Cupin DUF2793 PF10983.3 KZN83887.1 - 0.038 13.7 0.1 0.09 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) MannoseP_isomer PF01050.13 KZN83887.1 - 0.1 12.2 0.0 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase KR PF08659.5 KZN83888.1 - 2.4e-20 72.9 0.1 1.1e-19 70.8 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KZN83888.1 - 1.3e-16 60.9 0.3 9.7e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KZN83888.1 - 6.7e-11 41.8 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 KZN83888.1 - 0.16 11.8 0.5 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 ThiF family Strep_67kDa_ant PF06100.6 KZN83889.1 - 2.4e-90 303.3 0.0 2.9e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KZN83889.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2367 PF10164.4 KZN83891.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ank_2 PF12796.2 KZN83893.1 - 5.7e-76 250.9 0.6 1.4e-20 73.4 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83893.1 - 1.1e-61 201.6 8.8 1.1e-08 34.4 0.0 11.2 10 1 1 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KZN83893.1 - 2.5e-48 161.0 12.8 3.1e-12 46.3 0.0 7.5 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN83893.1 - 5.9e-46 154.0 8.5 3.3e-10 40.1 0.0 7.9 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83893.1 - 1.5e-38 126.9 5.8 2.2e-05 24.2 0.0 11.0 11 0 0 11 11 11 8 Ankyrin repeat NACHT PF05729.7 KZN83893.1 - 6.6e-06 25.8 0.0 3.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KZN83893.1 - 0.0016 18.5 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Lyase_aromatic PF00221.14 KZN83894.1 - 2e-153 511.2 7.3 2.7e-153 510.8 5.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase HTH_17 PF12728.2 KZN83894.1 - 0.048 13.9 0.0 0.34 11.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase PF00069.20 KZN83895.1 - 3.5e-28 98.4 0.0 3.5e-27 95.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83895.1 - 7.6e-12 44.8 0.0 4.7e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KZN83895.1 - 0.042 13.5 0.1 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KZN83895.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sugar_tr PF00083.19 KZN83896.1 - 8.9e-101 337.6 38.7 1e-100 337.4 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83896.1 - 2.6e-29 102.0 37.1 2.6e-29 102.0 25.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Mpv17_PMP22 PF04117.7 KZN83896.1 - 0.21 11.2 0.1 0.21 11.2 0.0 2.3 2 1 0 2 2 2 0 Mpv17 / PMP22 family AA_permease_2 PF13520.1 KZN83898.1 - 2.4e-42 144.9 46.3 3e-42 144.6 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN83898.1 - 4.9e-23 81.2 41.0 7.9e-23 80.5 28.4 1.2 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 KZN83900.1 - 3.9e-09 36.4 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN83900.1 - 3.2e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN83900.1 - 1.7e-05 24.8 0.1 4.6e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KZN83900.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_9 PF13527.1 KZN83900.1 - 0.13 12.1 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RTA1 PF04479.8 KZN83902.1 - 2.1e-49 168.0 4.6 2.9e-49 167.5 3.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_2 PF00703.16 KZN83903.1 - 1e-13 51.7 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KZN83903.1 - 2.6e-11 43.3 0.0 8.6e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KZN83903.1 - 0.05 12.4 0.1 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 KZN83904.1 - 6.5e-63 212.8 26.3 7.5e-63 212.6 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83904.1 - 4.7e-31 107.7 48.6 5.4e-26 91.1 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN83904.1 - 7.9e-09 34.2 2.8 1.6e-08 33.2 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KZN83905.1 - 1.9e-21 76.1 0.1 3.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83905.1 - 1.1e-06 28.3 11.9 2.2e-06 27.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad9_Rad53_bind PF08605.5 KZN83905.1 - 0.2 11.4 0.0 0.57 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Aconitase PF00330.15 KZN83906.1 - 1.9e-69 234.3 0.0 1.4e-43 149.0 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN83906.1 - 2.4e-22 79.4 0.0 4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain AA_permease PF00324.16 KZN83907.1 - 1e-88 297.7 42.0 1.2e-88 297.5 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN83907.1 - 1.5e-25 89.6 45.4 1.8e-25 89.3 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1189 PF06691.6 KZN83907.1 - 0.2 10.9 2.1 3.3 6.9 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Glyco_hydro_2_C PF02836.12 KZN83908.1 - 1.2e-87 293.5 0.0 1.6e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KZN83908.1 - 1e-34 119.4 0.0 1.8e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KZN83908.1 - 2.5e-12 47.2 0.4 6.5e-12 45.8 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.1 KZN83908.1 - 0.0007 19.3 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase-like PF12876.2 KZN83908.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Big_5 PF13205.1 KZN83908.1 - 0.026 15.1 0.6 0.065 13.8 0.4 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Pyr_redox_3 PF13738.1 KZN83909.1 - 4.7e-22 79.0 0.0 1.7e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN83909.1 - 2.4e-17 62.3 0.5 7.3e-16 57.4 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN83909.1 - 3.3e-07 30.2 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN83909.1 - 0.00012 21.1 0.0 0.0059 15.5 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) S_locus_glycop PF00954.15 KZN83909.1 - 0.066 13.4 2.5 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 S-locus glycoprotein family NAD_binding_9 PF13454.1 KZN83909.1 - 0.16 11.7 0.4 3.3 7.4 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.8 KZN83910.1 - 5e-50 169.9 0.0 7.3e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN83910.1 - 6.2e-16 58.2 0.6 2.7e-15 56.1 0.3 2.0 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KZN83910.1 - 0.00084 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN83910.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN83910.1 - 0.072 12.2 0.0 0.46 9.6 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox_3 PF13738.1 KZN83911.1 - 2.8e-19 69.9 0.0 1.7e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN83911.1 - 4.5e-17 61.4 0.0 6.7e-16 57.5 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN83911.1 - 2e-09 37.3 0.0 6.1e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN83911.1 - 8.4e-07 28.2 0.0 0.00015 20.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN83911.1 - 0.00098 19.0 0.0 0.056 13.3 0.0 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN83911.1 - 0.0012 18.6 0.3 0.086 12.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KZN83911.1 - 0.0031 16.6 0.0 1 8.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase MFS_1 PF07690.11 KZN83912.1 - 1.6e-24 86.3 37.9 1.6e-24 86.3 26.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2838 PF10998.3 KZN83912.1 - 0.022 14.6 1.2 0.072 12.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) DUF1129 PF06570.6 KZN83912.1 - 0.12 11.6 2.9 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Lactamase_B PF00753.22 KZN83913.1 - 9.8e-10 38.3 0.3 1.3e-09 37.9 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN83913.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ADH_N PF08240.7 KZN83914.1 - 1.2e-22 79.7 0.9 1.9e-22 79.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN83914.1 - 6.6e-16 58.0 0.0 1.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN83914.1 - 1.6e-07 32.2 0.0 4.8e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KZN83914.1 - 0.0051 16.4 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KZN83914.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIS_2 PF13580.1 KZN83914.1 - 0.13 11.9 0.2 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 SIS domain adh_short PF00106.20 KZN83915.1 - 2e-19 70.1 0.0 4.2e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83915.1 - 4.9e-08 32.8 0.0 4.4e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KZN83915.1 - 1.6e-05 24.8 0.0 0.00051 19.8 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN83915.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN83915.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aa_trans PF01490.13 KZN83916.1 - 1e-27 96.6 33.3 1.3e-27 96.3 23.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 KZN83917.1 - 5.8e-14 51.5 20.4 1.5e-12 46.9 12.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN83917.1 - 0.0043 16.8 0.2 0.017 14.9 0.1 2.0 1 0 0 1 1 1 1 MFS_1 like family Ank_2 PF12796.2 KZN83918.1 - 0.0002 21.6 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83918.1 - 0.11 12.3 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 KZN83919.1 - 1.6e-35 121.2 0.2 4.3e-12 46.1 0.0 4.0 1 1 4 5 5 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83919.1 - 1.1e-25 88.0 10.5 4.5e-07 29.3 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KZN83919.1 - 1.4e-21 76.3 4.4 0.0062 17.0 0.0 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83919.1 - 6.8e-19 66.0 9.4 0.02 15.1 0.0 9.0 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.1 KZN83919.1 - 2.4e-18 65.7 6.1 1.9e-05 24.7 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) GDPD PF03009.12 KZN83920.1 - 1.5e-49 168.7 0.0 2.8e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KZN83920.1 - 1.2e-25 89.6 0.6 2.8e-10 40.3 0.0 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83920.1 - 4.3e-14 51.5 4.3 0.00026 20.6 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KZN83920.1 - 2.5e-10 40.5 1.7 0.034 14.6 0.1 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN83920.1 - 5.3e-09 35.4 0.5 0.18 12.1 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat SPX PF03105.14 KZN83920.1 - 1.3e-08 35.0 0.0 0.0018 18.0 0.0 2.4 2 1 0 2 2 2 2 SPX domain Ank_5 PF13857.1 KZN83920.1 - 1.8e-08 34.3 0.3 0.034 14.3 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Beta_elim_lyase PF01212.16 KZN83921.1 - 1.1e-79 267.6 0.0 1.3e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Catalase PF00199.14 KZN83922.1 - 5.3e-170 565.2 0.1 6.2e-170 564.9 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN83922.1 - 4.9e-12 45.5 0.1 1.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.14 KZN83923.1 - 4.8e-53 180.2 0.0 6.2e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN83923.1 - 4e-35 121.2 0.0 6.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KZN83923.1 - 0.00083 18.3 0.1 0.002 17.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KZN83923.1 - 0.005 15.7 0.1 0.0094 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN83923.1 - 0.018 13.8 0.2 0.18 10.6 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KZN83923.1 - 0.056 13.4 0.9 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN83923.1 - 0.071 12.2 0.2 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KZN83923.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KZN83923.1 - 0.15 11.7 0.1 0.95 9.1 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 KZN83923.1 - 0.18 11.8 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KZN83924.1 - 7.3e-52 176.2 25.4 7.3e-52 176.2 17.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN83924.1 - 9.1e-11 40.9 8.7 9.1e-11 40.9 6.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KZN83924.1 - 4.5e-07 28.6 6.4 0.0024 16.3 0.2 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KZN83924.1 - 4.4e-06 25.1 2.0 8.6e-06 24.2 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 KZN83924.1 - 0.0083 14.5 0.0 0.014 13.8 0.0 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF4231 PF14015.1 KZN83924.1 - 4 7.4 6.4 0.71 9.8 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Grp1_Fun34_YaaH PF01184.14 KZN83926.1 - 1e-38 132.7 17.6 1.3e-38 132.4 12.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.20 KZN83928.1 - 2.4e-20 72.7 0.0 1.1e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83928.1 - 7e-10 38.4 0.0 0.0017 17.4 0.0 3.2 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KZN83928.1 - 0.032 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NmrA PF05368.8 KZN83929.1 - 1.2e-15 57.4 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN83929.1 - 4.2e-14 52.9 0.0 6.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN83929.1 - 4.1e-08 32.9 0.2 1.9e-05 24.2 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN83929.1 - 7.8e-05 22.9 0.1 0.00025 21.3 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KZN83929.1 - 0.00024 21.0 0.4 0.00097 19.0 0.3 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KZN83929.1 - 0.00092 19.2 0.3 0.002 18.1 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KZN83929.1 - 0.0068 16.3 0.7 0.019 14.8 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83929.1 - 0.0082 15.8 0.2 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 KR domain DXP_reductoisom PF02670.11 KZN83929.1 - 0.017 15.6 0.2 0.05 14.1 0.1 1.7 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 KZN83929.1 - 0.018 13.9 0.1 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN83929.1 - 0.031 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KZN83929.1 - 0.072 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein SseC PF04888.7 KZN83930.1 - 0.00093 18.6 6.9 0.0011 18.3 4.8 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF3464 PF11947.3 KZN83930.1 - 0.05 13.0 3.4 0.057 12.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) IncFII_repA PF02387.10 KZN83930.1 - 0.093 11.8 6.5 0.1 11.7 4.5 1.1 1 0 0 1 1 1 0 IncFII RepA protein family ATC_hydrolase PF14196.1 KZN83930.1 - 0.17 12.3 2.9 0.22 11.9 2.0 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase COXG PF06240.8 KZN83930.1 - 0.19 11.3 1.4 0.85 9.2 1.0 1.9 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) RuvB_N PF05496.7 KZN83930.1 - 0.47 9.4 6.0 0.57 9.1 4.2 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF853 PF05872.7 KZN83930.1 - 0.86 7.8 4.6 0.97 7.7 3.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PRTP PF01366.13 KZN83930.1 - 0.94 7.3 4.5 1 7.2 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF2228 PF10228.4 KZN83930.1 - 1.2 8.6 4.8 1.3 8.5 3.3 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Ribosomal_L28e PF01778.12 KZN83930.1 - 1.3 9.4 9.2 1.6 9.1 6.4 1.2 1 0 0 1 1 1 0 Ribosomal L28e protein family HK97-gp10_like PF04883.7 KZN83930.1 - 2.3 9.2 20.0 2.3e+02 2.8 13.9 2.2 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component MRFAP1 PF15155.1 KZN83930.1 - 2.8 8.2 11.1 3.9 7.8 7.7 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 SRI PF08236.6 KZN83930.1 - 3.3 7.7 9.4 34 4.4 6.5 2.2 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Choline_kinase PF01633.15 KZN83932.1 - 6.8e-23 81.3 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KZN83932.1 - 3.8e-06 26.8 0.0 5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_2 PF04693.7 KZN83932.1 - 0.044 12.7 0.1 0.061 12.3 0.1 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 EcKinase PF02958.15 KZN83932.1 - 0.053 12.6 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Sugar_tr PF00083.19 KZN83933.1 - 2e-88 296.9 15.5 2.3e-88 296.7 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83933.1 - 8.5e-32 110.2 28.6 2.5e-27 95.5 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN83933.1 - 0.0015 16.8 4.6 0.0041 15.3 0.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KZN83933.1 - 0.14 10.1 2.2 6.7 4.6 1.5 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.13 KZN83934.1 - 3e-13 49.2 0.2 5.2e-13 48.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.13 KZN83935.1 - 4.9e-33 114.4 0.0 6.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CAF1 PF04857.15 KZN83935.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 CAF1 family ribonuclease DUF2173 PF09941.4 KZN83935.1 - 0.067 13.1 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) CdhC PF03598.10 KZN83935.1 - 0.074 11.4 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Peptidase_A4 PF01828.12 KZN83936.1 - 5.8e-90 299.9 7.4 6.8e-90 299.6 5.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family LysM PF01476.15 KZN83937.1 - 5.2e-06 26.2 0.2 1.6e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.14 KZN83937.1 - 0.00029 20.7 11.0 0.00029 20.7 7.6 2.8 3 0 0 3 3 3 1 Chitin recognition protein AAA_14 PF13173.1 KZN83938.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3094 PF11293.3 KZN83938.1 - 0.66 9.4 4.4 0.25 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) GMC_oxred_C PF05199.8 KZN83939.1 - 7.4e-29 100.8 0.1 2.8e-28 98.9 0.0 2.1 2 1 0 2 2 2 1 GMC oxidoreductase Sugar_tr PF00083.19 KZN83940.1 - 5.1e-78 262.6 22.7 6.3e-78 262.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN83940.1 - 5.3e-16 58.2 48.6 9.8e-15 54.1 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipoprotein_Ltp PF07553.6 KZN83940.1 - 1.1 9.1 3.1 0.87 9.5 0.6 1.8 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Acetyltransf_1 PF00583.19 KZN83942.1 - 4e-12 45.9 0.1 9.5e-12 44.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN83942.1 - 1.9e-11 43.9 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN83942.1 - 3.9e-05 23.7 0.0 5.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN83942.1 - 0.00058 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN83942.1 - 0.0056 16.5 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KZN83942.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN83942.1 - 0.061 13.2 0.2 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_2b PF00587.20 KZN83943.1 - 7.1e-32 110.3 0.0 1.1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KZN83943.1 - 1.1e-12 47.7 0.0 2.9e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 KZN83944.1 - 3.5e-47 159.8 0.7 1.1e-46 158.3 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family Prok-E2_C PF14459.1 KZN83944.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family C Aa_trans PF01490.13 KZN83945.1 - 4.9e-24 84.5 36.6 6.3e-24 84.1 25.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 KZN83946.1 - 6.2e-58 195.6 0.0 8.3e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KZN83946.1 - 3.4e-19 68.6 0.1 7.9e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain LVIVD PF08309.6 KZN83946.1 - 0.0022 16.9 0.1 0.0043 15.9 0.1 1.5 1 0 0 1 1 1 1 LVIVD repeat DUF3336 PF11815.3 KZN83951.1 - 2.2e-43 147.2 2.9 3.8e-43 146.4 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KZN83951.1 - 1.2e-23 84.1 0.0 2.2e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_5 PF12695.2 KZN83952.1 - 4.2e-07 29.8 0.0 7.8e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN83952.1 - 2e-05 24.5 0.1 8.5e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN83952.1 - 0.016 14.4 0.5 0.054 12.7 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Cutinase PF01083.17 KZN83952.1 - 0.027 14.2 0.0 0.059 13.0 0.0 1.5 2 0 0 2 2 2 0 Cutinase Seryl_tRNA_N PF02403.17 KZN83953.1 - 0.0029 17.5 6.4 0.0055 16.7 2.4 2.5 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 KZN83953.1 - 0.0059 16.1 2.0 0.0059 16.1 1.4 2.3 2 0 0 2 2 2 1 Intermediate filament protein DUF3189 PF11385.3 KZN83953.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Reo_sigmaC PF04582.7 KZN83953.1 - 0.018 14.2 1.1 0.039 13.1 0.7 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KZN83953.1 - 0.044 13.9 4.1 0.11 12.5 0.7 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NuA4 PF09340.5 KZN83953.1 - 0.048 13.3 1.4 0.24 11.0 0.4 2.5 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Vac_Fusion PF02346.11 KZN83953.1 - 0.095 12.1 2.0 2 7.9 0.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus fusion protein TMCO5 PF14992.1 KZN83953.1 - 0.12 11.4 7.2 0.28 10.2 5.0 1.6 1 0 0 1 1 1 0 TMCO5 family Clp1 PF06807.9 KZN83953.1 - 0.12 12.1 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 TMF_DNA_bd PF12329.3 KZN83953.1 - 0.16 11.7 10.4 0.033 13.9 2.5 2.7 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KZN83953.1 - 0.18 11.2 1.6 2.5 7.6 0.3 2.7 2 0 0 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.6 KZN83953.1 - 0.24 10.8 5.8 0.81 9.1 3.6 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.7 KZN83953.1 - 0.31 10.8 2.4 0.65 9.8 0.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 KZN83953.1 - 0.4 10.9 2.6 16 5.7 1.5 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 KZN83953.1 - 0.56 9.7 12.5 0.1 12.1 4.1 2.4 2 1 0 2 2 2 0 IncA protein Paralemmin PF03285.10 KZN83953.1 - 0.71 9.3 5.5 0.4 10.0 1.1 2.2 2 0 0 2 2 2 0 Paralemmin CENP-H PF05837.7 KZN83953.1 - 0.82 9.8 7.1 0.32 11.2 2.7 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) COG5 PF10392.4 KZN83953.1 - 0.85 9.5 10.2 0.25 11.3 2.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF724 PF05266.9 KZN83953.1 - 0.89 9.1 5.1 0.6 9.7 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.3 KZN83953.1 - 3 7.6 11.9 9.8 5.9 0.1 3.2 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 KZN83953.1 - 5.2 6.6 9.7 0.25 10.9 2.0 2.2 2 1 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 KZN83953.1 - 8.7 4.0 6.6 20 2.8 4.5 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KZN83953.1 - 9.2 5.2 11.1 1.2 8.1 4.2 1.9 1 1 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 KZN83953.1 - 9.3 6.4 8.3 1.9 8.7 0.7 3.3 4 0 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PC_rep PF01851.17 KZN83954.1 - 6.2e-38 126.9 19.9 1.4e-09 37.6 0.0 9.4 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KZN83954.1 - 1.7e-19 69.8 0.6 1.5e-12 47.6 0.0 5.3 2 1 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 KZN83954.1 - 7e-07 29.5 5.3 3.7e-05 24.0 0.0 5.3 5 1 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KZN83954.1 - 7.1e-07 28.7 0.0 3.2 8.0 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 KZN83954.1 - 0.022 15.1 2.1 0.87 10.2 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 KZN83954.1 - 0.11 12.4 0.2 7.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Acyl-CoA_dh_1 PF00441.19 KZN83955.1 - 1.1e-39 135.8 0.3 1.7e-39 135.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN83955.1 - 7.6e-20 70.1 0.1 1.4e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KZN83955.1 - 1.2e-18 67.6 0.0 2.8e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 KZN83955.1 - 1.6e-15 56.6 0.1 2.9e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KZN83955.1 - 1.5e-06 28.4 0.0 2.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CTD PF12815.2 KZN83956.1 - 1.3e-27 96.6 49.2 2.1e-24 86.2 18.7 3.8 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KZN83956.1 - 2.7e-17 62.2 0.0 4.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KZN83956.1 - 1.4e-16 60.8 11.5 1.4e-16 60.8 8.0 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KZN83956.1 - 3.1e-11 42.5 11.0 0.0013 18.3 0.0 4.0 4 0 0 4 4 4 3 KOW motif TFIIF_alpha PF05793.7 KZN83956.1 - 1.8 6.8 39.1 2.6 6.3 27.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Amidase PF01425.16 KZN83957.1 - 1.1e-96 324.4 0.0 1.4e-96 324.0 0.0 1.2 1 0 0 1 1 1 1 Amidase DAO PF01266.19 KZN83958.1 - 2.4e-34 118.7 2.8 3.6e-34 118.2 1.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN83958.1 - 0.0012 18.8 0.5 0.0055 16.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN83958.1 - 0.0037 17.0 0.2 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KZN83958.1 - 0.034 14.2 0.0 9.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN83958.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KZN83959.1 - 1.9e-36 125.5 15.8 1.9e-36 125.5 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 KZN83959.1 - 0.37 10.4 2.6 0.99 9.1 0.3 2.4 2 0 0 2 2 2 0 Glycine zipper Fungal_trans_2 PF11951.3 KZN83960.1 - 2.4e-09 36.2 4.3 3.9e-05 22.4 0.5 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83960.1 - 9.8e-09 34.9 11.1 2.2e-08 33.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain mRNA_triPase PF02940.10 KZN83961.1 - 1.4e-58 198.2 0.3 3.4e-58 196.8 0.1 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain BolA PF01722.13 KZN83961.1 - 0.057 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 BolA-like protein Acyl_transf_3 PF01757.17 KZN83963.1 - 1.4e-30 106.2 40.5 3.1e-30 105.1 28.1 1.6 1 1 0 1 1 1 1 Acyltransferase family WD40 PF00400.27 KZN83964.1 - 4.9e-22 76.9 15.4 3.8e-08 32.9 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 KZN83965.1 - 6.7e-06 26.2 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KZN83965.1 - 0.081 12.5 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD synthetase Herpes_gI PF01688.12 KZN83965.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Nse5 PF08691.5 KZN83966.1 - 0.047 12.2 0.1 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 F-box-like PF12937.2 KZN83966.1 - 0.076 12.7 0.1 0.46 10.2 0.1 2.3 1 1 0 1 1 1 0 F-box-like His_Phos_2 PF00328.17 KZN83967.1 - 1.5e-60 205.3 0.0 1.9e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Reprolysin_5 PF13688.1 KZN83968.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M6 PF05547.6 KZN83968.1 - 0.014 13.5 0.9 0.023 12.7 0.6 1.4 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Reprolysin_4 PF13583.1 KZN83968.1 - 0.055 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KZN83968.1 - 0.06 13.0 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF2007 PF09413.5 KZN83969.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2007) Cep57_MT_bd PF06657.8 KZN83970.1 - 1.6e-28 98.4 0.1 1.6e-28 98.4 0.1 3.8 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KZN83970.1 - 3.2e-19 68.6 12.5 3.2e-19 68.6 8.7 4.6 5 0 0 5 5 5 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 KZN83970.1 - 0.015 15.0 2.2 0.015 15.0 1.5 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.13 KZN83970.1 - 0.31 11.0 5.9 1.5 8.8 0.7 3.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.6 KZN83970.1 - 0.64 9.7 7.3 0.16 11.7 2.0 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region MAT1 PF06391.8 KZN83971.1 - 7.4e-38 130.1 16.3 9.6e-38 129.7 11.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KZN83971.1 - 0.00035 20.1 5.1 0.0013 18.3 3.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN83971.1 - 0.00083 18.9 7.6 0.0018 17.8 5.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN83971.1 - 0.0023 17.9 6.6 0.0057 16.6 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN83971.1 - 0.0027 17.5 5.5 0.0053 16.5 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KZN83971.1 - 0.0045 16.5 6.6 0.025 14.1 1.4 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KZN83971.1 - 0.0057 16.3 8.1 0.06 13.0 6.0 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Phage_B PF02304.10 KZN83971.1 - 0.47 10.7 6.6 0.25 11.6 2.1 2.2 2 0 0 2 2 2 0 Scaffold protein B Prefoldin_3 PF13758.1 KZN83972.1 - 7.3e-36 121.9 0.4 1.8e-35 120.6 0.2 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 KZN83972.1 - 3.2e-13 50.4 2.4 3.2e-13 50.4 1.7 6.2 6 2 1 7 7 7 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 KZN83972.1 - 0.0081 15.8 0.3 0.031 13.9 0.2 2.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KZN83972.1 - 0.66 9.7 5.2 1.2 8.9 0.1 3.2 2 1 1 3 3 3 0 Prefoldin subunit adh_short PF00106.20 KZN83973.1 - 3.3e-13 49.8 0.1 6.4e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83973.1 - 7.7e-06 25.6 0.2 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KZN83974.1 - 3e-15 55.7 0.0 5.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN83974.1 - 0.12 12.3 4.8 0.28 11.1 3.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KZN83975.1 - 4e-42 144.1 0.0 1.4e-41 142.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN83975.1 - 9.3e-30 103.5 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN83975.1 - 8.8e-05 21.6 0.0 0.00036 19.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN83975.1 - 0.0007 18.7 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN83975.1 - 0.0044 16.7 2.0 0.0085 15.8 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Ank_2 PF12796.2 KZN83976.1 - 3.6e-08 33.6 0.0 7.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN83976.1 - 1e-07 31.3 0.0 0.00032 20.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 KZN83976.1 - 1.3e-06 28.2 0.1 5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.1 KZN83976.1 - 2.2e-06 28.0 0.0 2e-05 24.9 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KZN83976.1 - 1.7e-05 24.9 1.3 9.2e-05 22.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KZN83976.1 - 2e-05 24.6 2.7 2.5e-05 24.3 0.0 2.6 4 1 0 4 4 3 1 AAA ATPase domain Ank_5 PF13857.1 KZN83976.1 - 0.00014 22.0 0.0 0.19 12.0 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NB-ARC PF00931.17 KZN83976.1 - 0.00027 19.8 0.4 0.00071 18.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KZN83976.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase Ank_3 PF13606.1 KZN83976.1 - 0.0014 18.6 0.0 1.6 9.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat AAA_14 PF13173.1 KZN83976.1 - 0.0027 17.6 0.0 0.056 13.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KZN83976.1 - 0.0036 17.1 0.1 0.014 15.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KZN83976.1 - 0.0093 16.1 0.6 0.055 13.6 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SCO1-SenC PF02630.9 KZN83976.1 - 0.012 15.2 0.3 0.083 12.5 0.1 2.2 2 0 0 2 2 2 0 SCO1/SenC Zeta_toxin PF06414.7 KZN83976.1 - 0.025 13.6 0.7 1.8 7.5 0.0 3.0 2 1 1 3 3 3 0 Zeta toxin AAA_29 PF13555.1 KZN83976.1 - 0.035 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KZN83976.1 - 0.057 12.8 0.5 1.1 8.5 0.4 2.4 1 1 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 KZN83976.1 - 0.058 12.9 0.1 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN83976.1 - 0.065 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain NGP1NT PF08153.7 KZN83977.1 - 3.5e-47 159.6 0.1 6.6e-47 158.6 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KZN83977.1 - 5.6e-19 68.2 0.0 1.4e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN83977.1 - 1.7e-05 24.1 0.0 0.00018 20.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KZN83977.1 - 0.00015 21.5 0.1 0.21 11.3 0.1 3.4 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KZN83977.1 - 0.00026 20.2 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 KZN83977.1 - 0.0023 17.1 0.0 0.0044 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KZN83977.1 - 0.017 15.5 0.0 6 7.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KZN83977.1 - 0.022 14.1 0.0 3.3 7.0 0.0 3.0 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF2462 PF09495.5 KZN83979.1 - 3.3e-18 66.1 3.3 3.3e-18 66.1 2.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Zn_clus PF00172.13 KZN83980.1 - 0.0032 17.3 9.9 0.0069 16.2 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.17 KZN83980.1 - 0.077 13.1 0.2 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 RNA helicase SurE PF01975.12 KZN83981.1 - 2.9e-46 157.2 0.0 3.6e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_transf_28 PF03033.15 KZN83981.1 - 0.035 13.8 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF2413 PF10310.4 KZN83982.1 - 1.6e-147 491.9 0.1 1.8e-147 491.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KZN83982.1 - 0.1 12.6 2.4 0.12 12.3 0.2 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF2020 PF09449.5 KZN83982.1 - 0.34 10.5 3.1 0.82 9.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) CMD PF02627.15 KZN83983.1 - 8.6e-08 31.9 0.1 1.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family API5 PF05918.6 KZN83984.1 - 0.15 10.5 1.7 0.23 9.8 1.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2 PF00096.21 KZN83985.1 - 0.0067 16.7 3.1 0.21 12.0 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KZN83985.1 - 0.015 15.4 2.6 0.64 10.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KZN83985.1 - 0.025 14.8 2.0 0.9 10.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KZN83985.1 - 0.056 13.5 1.2 3.9 7.6 0.1 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HDV_ag PF01517.13 KZN83985.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen DUF629 PF04780.7 KZN83985.1 - 0.059 11.8 0.0 0.083 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 KZN83985.1 - 0.39 10.6 2.2 6.1 6.8 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger Tmemb_14 PF03647.8 KZN83986.1 - 2.8e-21 75.7 10.4 3.2e-21 75.5 7.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Peptidase_M28 PF04389.12 KZN83987.1 - 1.8e-15 57.1 0.0 3.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KZN83987.1 - 2.1e-15 56.3 0.0 3.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KZN83987.1 - 4.7e-06 26.2 0.1 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KZN83987.1 - 0.0034 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin RTC4 PF14474.1 KZN83988.1 - 7.9e-35 119.5 0.0 1.4e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 KZN83989.1 - 4.6e-127 423.6 2.8 6.8e-127 423.0 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glyco_hydro_18 PF00704.23 KZN83989.1 - 3.1e-79 266.9 0.8 1.7e-78 264.4 1.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KZN83989.1 - 8.5e-15 54.4 44.9 1.1e-10 41.2 10.7 2.5 2 0 0 2 2 2 2 Chitin recognition protein Lipase_3 PF01764.20 KZN83989.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) NIR_SIR PF01077.17 KZN83991.1 - 1.4e-31 109.0 0.1 3.5e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KZN83991.1 - 1e-28 100.5 0.6 5.2e-28 98.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KZN83991.1 - 3.6e-17 61.9 0.0 7.2e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 KZN83991.1 - 3.7e-15 56.0 3.8 7e-14 51.9 0.4 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KZN83991.1 - 4.2e-14 51.8 0.2 1.2e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.10 KZN83991.1 - 7.1e-13 48.4 4.7 3e-12 46.3 2.4 2.5 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 KZN83991.1 - 8e-11 41.4 0.0 1.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KZN83991.1 - 4.9e-06 26.7 0.0 0.00073 19.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN83991.1 - 0.002 17.9 1.4 2.5 7.8 0.1 3.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN83991.1 - 0.018 13.9 0.1 0.24 10.2 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KZN83991.1 - 0.025 14.8 0.2 0.82 9.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KZN83991.1 - 0.03 13.1 0.1 0.092 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Ribonuc_L-PSP PF01042.16 KZN83992.1 - 2.4e-24 85.3 0.0 2.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_6 PF13458.1 KZN83992.1 - 0.066 12.5 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein MFS_1 PF07690.11 KZN83993.1 - 8.6e-28 97.0 26.5 8.6e-28 97.0 18.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF718 PF05336.8 KZN83994.1 - 7.7e-35 118.9 0.2 8.7e-35 118.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Abhydrolase_6 PF12697.2 KZN83996.1 - 2.1e-32 112.8 1.6 2.6e-32 112.5 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN83996.1 - 4.5e-20 72.1 0.6 2.1e-17 63.4 0.1 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN83996.1 - 2.4e-15 56.5 0.1 1.2e-14 54.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN83996.1 - 2.6e-06 27.2 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KZN83996.1 - 1.8e-05 23.3 0.0 2.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 KZN83996.1 - 3.6e-05 23.4 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KZN83996.1 - 0.0017 17.5 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2424 PF10340.4 KZN83996.1 - 0.0031 16.2 0.0 0.0045 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Esterase PF00756.15 KZN83996.1 - 0.0037 16.7 0.1 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 KZN83996.1 - 0.032 13.9 0.1 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.8 KZN83996.1 - 0.062 12.9 0.0 0.35 10.4 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase Eno-Rase_NADH_b PF12242.3 KZN83996.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioesterase PF00975.15 KZN83996.1 - 0.14 12.3 0.1 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Acyl_transf_1 PF00698.16 KZN83996.1 - 0.15 11.3 0.2 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase domain DLH PF01738.13 KZN83996.1 - 0.16 11.2 0.6 25 4.0 0.0 3.0 2 1 0 2 2 2 0 Dienelactone hydrolase family TauD PF02668.11 KZN83997.1 - 3.8e-19 69.3 0.5 8.3e-16 58.4 0.2 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family IucA_IucC PF04183.7 KZN83998.1 - 3.9e-25 88.5 0.3 5.3e-24 84.8 0.2 2.3 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 KZN83998.1 - 4.8e-21 75.3 0.0 9.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter adh_short PF00106.20 KZN83999.1 - 8.4e-13 48.5 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN83999.1 - 0.00018 21.1 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KZN83999.1 - 0.073 13.4 0.1 0.28 11.6 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ORC6 PF05460.8 KZN84001.1 - 0.58 9.2 5.4 0.66 9.0 3.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_L18p PF00861.17 KZN84002.1 - 5.1e-43 146.0 0.2 9.2e-43 145.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KZN84002.1 - 5.3e-31 107.0 7.4 5.3e-31 107.0 5.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MtrA PF04208.9 KZN84002.1 - 0.039 13.4 0.2 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF4284 PF14112.1 KZN84002.1 - 0.16 12.4 1.5 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4284) HAD_2 PF13419.1 KZN84003.1 - 1.6e-17 64.2 0.0 2.6e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN84003.1 - 4.5e-07 29.4 0.0 8.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 KZN84003.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase G10 PF01125.12 KZN84003.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 G10 protein FTA4 PF13093.1 KZN84004.1 - 1.9e-71 239.8 4.2 2.2e-71 239.7 2.9 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Mnd1 PF03962.10 KZN84004.1 - 0.0048 16.5 1.8 0.0073 15.9 1.0 1.4 1 1 0 1 1 1 1 Mnd1 family Cortex-I_coil PF09304.5 KZN84004.1 - 0.062 13.3 7.7 0.2 11.6 5.2 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4477 PF14780.1 KZN84004.1 - 0.095 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Seryl_tRNA_N PF02403.17 KZN84004.1 - 0.11 12.5 5.3 0.48 10.4 1.9 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Transcrip_act PF04949.8 KZN84004.1 - 2 8.0 7.0 3.4 7.2 0.2 2.3 1 1 1 2 2 2 0 Transcriptional activator NUDIX PF00293.23 KZN84005.1 - 1.2e-16 60.5 0.2 1.5e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KZN84005.1 - 0.012 15.0 0.2 0.067 12.6 0.2 1.9 1 1 0 1 1 1 0 NUDIX domain DegT_DnrJ_EryC1 PF01041.12 KZN84006.1 - 6.5e-64 216.2 0.0 9e-57 192.7 0.1 2.1 1 1 1 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KZN84006.1 - 1.9e-07 30.1 0.0 3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN84006.1 - 6.8e-05 21.9 0.0 0.00018 20.6 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II GFO_IDH_MocA_C PF02894.12 KZN84006.1 - 0.00017 21.3 0.0 0.00045 19.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Beta_elim_lyase PF01212.16 KZN84006.1 - 0.0065 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3829 PF12889.2 KZN84007.1 - 0.0015 17.7 3.1 0.0027 16.9 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) ABC_membrane_2 PF06472.10 KZN84009.1 - 2.8e-110 367.9 0.8 2.8e-110 367.9 0.6 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KZN84009.1 - 4.3e-19 69.1 0.0 8.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KZN84009.1 - 0.00016 21.7 0.0 0.00053 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KZN84009.1 - 0.0099 16.2 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN84009.1 - 0.022 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KZN84009.1 - 0.028 13.6 0.1 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN84009.1 - 0.034 14.1 1.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KZN84009.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HAD PF12710.2 KZN84010.1 - 2.6e-10 40.7 0.0 4.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KZN84010.1 - 0.0002 20.6 0.0 0.39 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KZN84010.1 - 0.0016 18.9 0.0 0.19 12.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN84010.1 - 0.13 12.5 0.1 21 5.2 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Phosphorylase PF00343.15 KZN84011.1 - 0 1071.8 0.6 0 1071.6 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.15 KZN84012.1 - 1.1e-123 412.8 0.2 1.3e-123 412.5 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KZN84012.1 - 4.2e-15 55.4 1.0 2.9e-10 39.6 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN84012.1 - 0.00036 19.7 0.2 0.64 9.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN84012.1 - 0.0014 19.1 0.1 0.57 10.6 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 KZN84012.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 KZN84013.1 - 7.5e-73 244.8 0.0 9.2e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84013.1 - 1.6e-31 109.2 0.0 2.1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN84013.1 - 3.2e-05 23.1 0.0 0.00012 21.1 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN84013.1 - 0.00037 19.5 0.0 0.041 12.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KZN84013.1 - 0.0006 19.6 0.0 0.0018 18.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN84013.1 - 0.05 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 KZN84014.1 - 7.2e-139 462.4 0.0 9.7e-139 462.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KZN84014.1 - 5e-07 29.4 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KZN84014.1 - 6.4e-05 22.3 2.6 0.004 16.4 0.0 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 KZN84015.1 - 4.1e-203 676.1 12.2 4.1e-203 676.1 8.5 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KZN84015.1 - 1.9e-27 94.8 4.9 1.9e-27 94.8 3.4 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain WGG PF10273.4 KZN84015.1 - 0.17 11.9 6.8 20 5.3 0.0 4.5 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 KZN84015.1 - 0.95 8.9 9.0 3.6 7.0 0.6 2.4 2 0 0 2 2 2 0 Kinase/pyrophosphorylase APH PF01636.18 KZN84016.1 - 9e-27 94.3 0.3 1.2e-26 93.9 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN84016.1 - 9.9e-05 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Exonuc_X-T_C PF08411.5 KZN84016.1 - 0.071 12.1 0.4 0.14 11.1 0.1 1.5 2 0 0 2 2 2 0 Exonuclease C-terminal EcKinase PF02958.15 KZN84016.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Cupin_2 PF07883.6 KZN84017.1 - 4.1e-07 29.4 0.5 1.2e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KZN84017.1 - 2.1e-06 27.2 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 KZN84017.1 - 0.00094 19.1 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 KZN84017.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Mit_KHE1 PF10173.4 KZN84019.1 - 7.1e-65 218.3 0.7 1.2e-64 217.6 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related YqjK PF13997.1 KZN84019.1 - 0.3 11.3 5.7 4 7.6 0.1 3.1 3 0 0 3 3 3 0 YqjK-like protein End3 PF12761.2 KZN84020.1 - 1.9e-75 252.8 0.2 2.7e-75 252.2 0.2 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KZN84020.1 - 2e-51 172.0 0.2 4.1e-48 161.4 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KZN84020.1 - 1e-07 30.7 0.3 3.3e-07 29.1 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KZN84020.1 - 2.3e-05 24.4 0.7 7.7e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KZN84020.1 - 4.7e-05 22.9 0.1 9.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN84020.1 - 6.7e-05 22.4 0.1 0.00039 20.0 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KZN84020.1 - 0.00052 19.2 0.2 0.0019 17.4 0.1 2.0 1 0 0 1 1 1 1 EF hand TPR_MLP1_2 PF07926.7 KZN84020.1 - 0.028 14.1 5.4 0.098 12.4 0.1 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KZN84020.1 - 0.37 10.3 4.1 18 4.8 2.5 2.4 2 0 0 2 2 2 0 IncA protein Rabaptin PF03528.10 KZN84020.1 - 0.39 10.6 5.1 4.4 7.2 3.7 2.4 1 1 1 2 2 2 0 Rabaptin DUF4407 PF14362.1 KZN84020.1 - 0.49 9.2 2.5 0.74 8.7 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.6 KZN84020.1 - 1.3 8.4 5.1 0.34 10.3 0.4 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.6 KZN84020.1 - 1.4 7.4 6.8 0.74 8.4 1.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 KZN84020.1 - 2.3 7.6 8.2 0.91 8.9 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Med9 PF07544.8 KZN84020.1 - 3 7.6 5.4 2.5 7.9 0.2 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SNF2_N PF00176.18 KZN84021.1 - 3.9e-67 226.1 0.0 7e-67 225.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN84021.1 - 3e-18 65.4 0.0 4.8e-17 61.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN84021.1 - 3.5e-05 23.7 0.0 0.00022 21.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2538 PF10804.3 KZN84021.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) HDA2-3 PF11496.3 KZN84021.1 - 0.55 9.0 7.6 0.071 11.9 0.3 2.6 2 1 1 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DSPc PF00782.15 KZN84023.1 - 6.1e-12 45.2 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KZN84023.1 - 0.0029 16.5 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF4471 PF14740.1 KZN84024.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) APH PF01636.18 KZN84025.1 - 6.7e-15 55.4 0.0 2.1e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN84025.1 - 0.00032 20.3 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN84025.1 - 0.043 12.4 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 KZN84025.1 - 0.074 12.1 0.0 2.2 7.3 0.0 2.4 2 1 0 2 2 2 0 Protein kinase domain EamA PF00892.15 KZN84027.1 - 4.5e-05 23.4 1.4 4.5e-05 23.4 1.0 3.7 4 0 0 4 4 4 3 EamA-like transporter family EmrE PF13536.1 KZN84027.1 - 8.5e-05 22.7 3.6 8.5e-05 22.7 2.5 3.2 4 1 0 4 4 4 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 KZN84027.1 - 0.0011 18.1 0.1 0.0011 18.1 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter Neurensin PF14927.1 KZN84027.1 - 0.066 12.5 0.8 14 5.0 0.0 3.0 2 1 0 2 2 2 0 Neurensin DUF202 PF02656.10 KZN84027.1 - 2 8.6 14.9 0.68 10.1 2.1 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF202) Aldo_ket_red PF00248.16 KZN84028.1 - 1.8e-53 181.2 0.0 2e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp_Glu_race PF01177.17 KZN84029.1 - 4.9e-18 65.8 0.0 6.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Tubulin PF00091.20 KZN84030.1 - 2.3e-75 253.1 0.0 3.9e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KZN84030.1 - 5.8e-44 149.1 0.3 9.2e-44 148.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KZN84030.1 - 1.3e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain zf-AN1 PF01428.11 KZN84031.1 - 2.3e-11 43.3 12.7 3.2e-11 42.9 8.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4187 PF13821.1 KZN84031.1 - 0.12 11.9 2.2 0.18 11.4 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF1754 PF08555.5 KZN84032.1 - 1.4e-14 54.4 18.8 2.2e-14 53.8 13.0 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.5 KZN84032.1 - 0.046 12.9 16.3 0.053 12.7 11.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adaptin_binding PF10199.4 KZN84032.1 - 0.19 11.9 8.2 0.29 11.4 5.6 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Geminin PF07412.7 KZN84032.1 - 0.31 10.7 11.5 0.42 10.2 8.0 1.1 1 0 0 1 1 1 0 Geminin PLRV_ORF5 PF01690.12 KZN84032.1 - 0.42 9.7 7.4 0.44 9.6 5.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2201_N PF13203.1 KZN84032.1 - 1.1 8.3 11.0 1.3 8.1 7.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 KZN84032.1 - 1.4 8.9 14.1 1.8 8.5 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.7 KZN84032.1 - 3.2 6.8 11.3 3.9 6.5 7.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 KZN84032.1 - 4.4 5.2 15.7 5.1 5.0 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 KZN84032.1 - 4.5 5.6 22.5 4.8 5.5 15.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CMV_1a PF12467.3 KZN84032.1 - 5.6 7.3 8.9 7.3 6.9 6.2 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF4457 PF14652.1 KZN84033.1 - 0.023 13.6 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF2875 PF11394.3 KZN84033.1 - 0.09 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) Acyl-CoA_dh_1 PF00441.19 KZN84034.1 - 7.7e-14 52.0 0.0 1.6e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN84034.1 - 1e-05 24.9 0.4 0.00024 20.5 0.1 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain CBM_20 PF00686.14 KZN84035.1 - 9.2e-35 118.1 0.1 2.1e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KZN84035.1 - 1.7e-08 34.9 0.1 2.4e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Chitin binding domain PTPA PF03095.10 KZN84036.1 - 1.7e-110 368.9 0.0 2e-110 368.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF202 PF02656.10 KZN84037.1 - 2.7e-26 91.5 0.5 2.7e-26 91.5 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1675 PF07897.6 KZN84037.1 - 5.2 6.8 9.0 7.5 6.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CAF-1_p150 PF11600.3 KZN84037.1 - 6.3 6.1 10.5 9 5.6 7.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Actin PF00022.14 KZN84038.1 - 5.9e-116 387.1 0.0 7.2e-116 386.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KZN84038.1 - 0.0059 15.2 0.0 0.031 12.8 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein NAD_binding_2 PF03446.10 KZN84039.1 - 4.4e-22 78.6 0.1 6.9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN84039.1 - 5.1e-13 49.1 0.0 9.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IMPDH PF00478.20 KZN84039.1 - 0.021 13.7 0.3 0.61 8.9 0.1 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF3425 PF11905.3 KZN84040.1 - 7.4e-35 119.8 4.0 1.4e-34 118.9 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KZN84040.1 - 0.006 16.5 6.0 0.031 14.2 4.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor T2SM_b PF10741.4 KZN84040.1 - 0.12 11.9 0.7 0.27 10.8 0.5 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b bZIP_2 PF07716.10 KZN84040.1 - 1.4 8.8 7.7 15 5.5 5.3 2.2 1 1 0 1 1 1 0 Basic region leucine zipper GTP_cyclohydro2 PF00925.15 KZN84041.1 - 2.2e-56 189.7 0.0 3.3e-51 172.8 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1325 PF07039.6 KZN84042.1 - 6.8e-31 106.5 0.0 1.2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain TATR PF03430.8 KZN84042.1 - 0.15 10.6 2.1 0.21 10.1 1.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PMI_typeI PF01238.16 KZN84043.1 - 7.1e-148 492.5 0.0 8.2e-148 492.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KZN84043.1 - 0.0011 18.4 0.3 0.01 15.3 0.2 2.1 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KZN84043.1 - 0.0089 15.7 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 2 AraC-like ligand binding domain NAD_binding_1 PF00175.16 KZN84044.1 - 8.7e-14 52.0 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN84044.1 - 5.5e-10 39.2 0.0 1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KZN84044.1 - 4.1e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 KZN84044.1 - 2.2e-05 24.4 0.0 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain B PF02216.11 KZN84044.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 B domain Acetate_kinase PF00871.12 KZN84044.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family TPR_11 PF13414.1 KZN84045.1 - 1e-12 47.5 1.1 4.6e-06 26.1 0.1 3.7 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KZN84045.1 - 2.8e-12 45.5 8.7 0.00035 20.2 0.3 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84045.1 - 2.9e-10 39.3 2.5 0.0013 18.2 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN84045.1 - 3e-10 39.8 4.9 0.00076 19.3 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84045.1 - 1.3e-06 28.8 0.2 0.27 11.9 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84045.1 - 7.4e-05 23.0 0.3 11 6.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KZN84045.1 - 0.00031 20.8 1.1 0.32 11.1 0.1 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KZN84045.1 - 0.00057 19.4 0.8 0.37 10.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KZN84045.1 - 0.0012 19.2 0.0 14 6.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84045.1 - 0.0017 18.0 2.2 0.37 10.6 0.1 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN84045.1 - 0.0024 18.1 0.2 0.26 11.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN84045.1 - 0.0025 17.8 0.1 0.076 13.2 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.13 KZN84045.1 - 0.0027 17.5 2.5 8.4 6.3 0.1 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KZN84045.1 - 0.0059 16.4 1.5 0.12 12.3 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat GTPase_Cys_C PF12631.2 KZN84045.1 - 0.088 13.2 1.1 5.6 7.4 0.0 3.1 3 1 0 3 3 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE AalphaY_MDB PF04611.7 KZN84046.1 - 0.048 13.5 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region adh_short PF00106.20 KZN84048.1 - 1.4e-06 28.3 0.4 5.2e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84048.1 - 0.027 14.1 0.1 0.036 13.7 0.1 1.4 1 1 0 1 1 1 0 KR domain PrpR_N PF06506.6 KZN84048.1 - 0.036 13.4 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator Abhydrolase_3 PF07859.8 KZN84049.1 - 5e-24 85.0 0.0 7.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN84049.1 - 7.9e-21 74.1 0.0 1.1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KZN84049.1 - 5.2e-07 29.7 0.3 9.1e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84049.1 - 3.5e-05 23.5 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN84049.1 - 0.0012 18.0 0.0 0.0073 15.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KZN84049.1 - 0.0056 16.1 0.0 0.056 12.8 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KZN84049.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KZN84049.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Coatomer_E PF04733.9 KZN84050.1 - 1.7e-59 201.4 4.5 1.9e-59 201.2 3.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KZN84050.1 - 2.1e-09 37.5 17.0 0.00072 19.8 2.8 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84050.1 - 3.6e-09 36.4 13.2 0.0017 18.8 0.1 5.5 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84050.1 - 5.5e-08 33.2 16.2 0.00054 20.5 2.7 4.0 3 2 2 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KZN84050.1 - 1.1e-07 31.8 2.3 0.00013 21.9 0.4 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KZN84050.1 - 1.1e-05 25.5 6.3 0.0061 16.9 0.3 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN84050.1 - 0.0004 20.0 13.0 0.032 14.1 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN84050.1 - 0.00043 19.8 5.0 0.66 9.6 1.1 3.4 2 1 2 4 4 4 3 TPR repeat TPR_4 PF07721.9 KZN84050.1 - 0.00054 20.1 17.4 0.71 10.4 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN84050.1 - 0.0039 17.2 1.0 15 6.0 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KZN84050.1 - 0.005 16.6 5.6 0.44 10.4 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84050.1 - 0.0098 15.4 4.0 1 9.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3508 PF12018.3 KZN84050.1 - 0.024 13.6 0.2 0.056 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) GHL13 PF14883.1 KZN84050.1 - 0.03 13.5 0.3 0.046 12.8 0.2 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF1874 PF08960.5 KZN84050.1 - 0.062 13.0 0.4 0.27 11.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1874) TPR_5 PF12688.2 KZN84050.1 - 0.075 13.0 6.7 0.63 10.0 1.2 3.3 2 2 1 3 3 3 0 Tetratrico peptide repeat TPR_12 PF13424.1 KZN84050.1 - 0.2 11.6 10.3 9.6 6.2 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KZN84050.1 - 0.6 10.2 11.8 0.84 9.7 2.6 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN84050.1 - 4.3 7.4 13.9 6.9 6.7 0.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.22 KZN84053.1 - 4e-07 29.6 0.0 7.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U5_2-snRNA_bdg PF10597.4 KZN84053.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 GreA_GreB_N PF03449.10 KZN84053.1 - 4.5 7.4 6.0 58 3.8 0.1 3.5 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Pox_A_type_inc PF04508.7 KZN84053.1 - 4.9 7.2 5.4 21 5.2 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PI-PLC-X PF00388.14 KZN84054.1 - 3e-59 198.6 0.0 6.3e-59 197.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KZN84054.1 - 6.6e-41 139.0 0.1 2.3e-40 137.2 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KZN84054.1 - 1.3e-06 28.3 0.0 3.7e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 KZN84054.1 - 0.0024 17.4 0.1 0.0084 15.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN84054.1 - 0.0043 16.8 2.9 0.13 12.1 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KZN84054.1 - 0.0093 15.2 0.5 0.054 12.8 0.1 2.6 3 0 0 3 3 3 1 EF hand GDPD PF03009.12 KZN84054.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_7 PF13499.1 KZN84054.1 - 0.027 14.5 1.5 0.62 10.2 0.4 2.7 1 1 2 3 3 3 0 EF-hand domain pair Transp_cyt_pur PF02133.10 KZN84055.1 - 1e-150 502.1 42.7 1.2e-150 501.9 29.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF543 PF04418.7 KZN84057.1 - 6.5e-27 93.3 0.1 7.1e-27 93.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 KZN84058.1 - 1.5e-64 217.7 3.9 2.3e-62 210.5 0.0 3.2 4 0 0 4 4 4 2 Urb2/Npa2 family Metallothio_2 PF01439.13 KZN84059.1 - 0.042 14.3 23.4 0.65 10.5 2.4 4.2 4 0 0 4 4 4 0 Metallothionein DUF2731 PF10806.3 KZN84060.1 - 2.7e-06 27.6 0.1 8.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 KZN84060.1 - 5.8e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KZN84060.1 - 0.00068 19.4 0.7 0.0014 18.4 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN84060.1 - 0.0034 17.8 0.2 0.0077 16.6 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KZN84060.1 - 0.0041 17.0 0.0 0.056 13.3 0.1 2.1 1 1 1 2 2 2 1 Tom37 C-terminal domain Methyltransf_18 PF12847.2 KZN84061.1 - 2.2e-09 37.8 0.0 4.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84061.1 - 3.9e-08 33.1 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN84061.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84061.1 - 1.3e-05 25.5 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN84061.1 - 1.3e-05 25.5 0.0 5.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84061.1 - 4e-05 23.9 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KZN84061.1 - 0.00017 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN84061.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KZN84061.1 - 0.06 12.7 0.2 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CheR PF01739.13 KZN84061.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KZN84061.1 - 0.073 13.1 0.4 0.23 11.4 0.3 1.8 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KZN84061.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KZN84061.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_7 PF03492.10 KZN84061.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase CDC14 PF08045.6 KZN84062.1 - 8.5e-95 316.7 0.0 9.7e-95 316.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 KZN84063.1 - 1.7e-58 197.5 0.0 2.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.5 KZN84064.1 - 9.9e-26 89.5 6.3 2.9e-25 88.0 4.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KZN84064.1 - 1.3e-16 60.5 0.3 3.4e-16 59.1 0.2 1.8 1 0 0 1 1 1 1 Smr domain G-alpha PF00503.15 KZN84065.1 - 2.4e-134 447.8 2.2 3e-134 447.5 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KZN84065.1 - 2.1e-15 56.4 1.7 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KZN84065.1 - 8.5e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KZN84065.1 - 0.0012 19.3 0.7 2.4 8.6 0.1 2.9 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KZN84065.1 - 0.0063 15.6 3.6 0.14 11.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KZN84065.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KZN84065.1 - 0.021 14.2 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KZN84065.1 - 0.051 13.9 0.2 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KZN84065.1 - 0.096 12.6 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KZN84065.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.4 KZN84066.1 - 6.2e-09 35.6 3.6 9.4e-09 35.0 2.5 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 PEP-utilisers_N PF05524.8 KZN84066.1 - 0.089 12.5 8.8 0.3 10.8 2.6 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF572 PF04502.8 KZN84066.1 - 0.39 9.8 18.0 0.55 9.3 12.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.8 KZN84066.1 - 4 5.4 9.5 5.2 5.1 6.6 1.2 1 0 0 1 1 1 0 Menin BatA PF07584.6 KZN84067.1 - 0.081 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal AMP-binding PF00501.23 KZN84068.1 - 2.1e-86 289.9 0.0 2.7e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN84068.1 - 3.2e-11 43.9 0.1 8.6e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nup188 PF10487.4 KZN84069.1 - 7e-56 189.7 0.5 2.1e-55 188.1 0.4 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF465 PF04325.8 KZN84069.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) IGPS PF00218.16 KZN84070.1 - 4.2e-97 324.1 0.0 1.2e-96 322.7 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KZN84070.1 - 1.1e-60 204.5 0.0 1.2e-59 201.1 0.0 2.2 1 1 1 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KZN84070.1 - 8.8e-51 172.0 0.0 1.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN84070.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KZN84070.1 - 0.0009 18.7 0.4 0.022 14.2 0.0 2.9 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain IMPDH PF00478.20 KZN84070.1 - 0.0014 17.6 0.0 0.33 9.7 0.0 2.5 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KZN84070.1 - 0.0056 15.9 0.1 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 KZN84070.1 - 0.01 14.8 0.6 0.071 12.0 0.0 2.6 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase BRCT PF00533.21 KZN84071.1 - 2.1e-08 34.2 0.0 6.6e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KZN84071.1 - 2.6e-08 33.5 0.0 9.1e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain WGR PF05406.10 KZN84071.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 WGR domain Peptidase_S74 PF13884.1 KZN84071.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Brix PF04427.13 KZN84072.1 - 5.2e-45 153.4 0.0 6.5e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 KZN84073.1 - 3.1e-73 244.3 1.4 3.1e-73 244.3 1.0 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KZN84073.1 - 4.2e-60 202.5 0.0 7.5e-60 201.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN84073.1 - 4.9e-56 189.9 1.0 7.6e-56 189.3 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN84073.1 - 1.2e-14 53.7 0.3 3.1e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KZN84073.1 - 4.9e-12 45.8 0.1 6.2e-11 42.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KZN84073.1 - 1.4e-08 34.7 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KZN84073.1 - 1.7e-05 24.4 0.1 0.26 10.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KZN84073.1 - 0.00028 19.9 0.3 0.003 16.6 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KZN84073.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KZN84073.1 - 0.0024 16.8 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 KZN84073.1 - 0.0029 16.9 0.0 0.034 13.4 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KZN84073.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KZN84073.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KZN84073.1 - 0.044 12.8 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KZN84073.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KZN84073.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KZN84073.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KZN84073.1 - 0.23 11.6 0.5 0.64 10.2 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4396 PF14342.1 KZN84074.1 - 6.8e-44 149.3 3.9 8.5e-44 149.0 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) zf-C2H2_4 PF13894.1 KZN84075.1 - 8.3e-06 25.7 13.8 0.046 14.0 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN84075.1 - 0.0034 17.6 19.2 0.7 10.3 2.4 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type Med4 PF10018.4 KZN84075.1 - 0.0076 15.6 0.2 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Microtub_assoc PF07989.6 KZN84075.1 - 0.018 14.8 1.6 0.032 14.0 0.2 1.9 2 0 0 2 2 2 0 Microtubule associated Transpos_assoc PF13963.1 KZN84075.1 - 0.12 12.3 0.4 0.12 12.3 0.3 1.7 2 0 0 2 2 2 0 Transposase-associated domain zf-H2C2_5 PF13909.1 KZN84075.1 - 0.13 12.5 0.9 3.6 8.0 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KZN84075.1 - 0.21 11.9 0.2 0.21 11.9 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF3115 PF11312.3 KZN84077.1 - 3.1e-104 348.2 0.0 3.9e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Band_7 PF01145.20 KZN84078.1 - 5.3e-25 88.3 6.7 7.6e-25 87.8 4.1 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KZN84078.1 - 0.0084 15.5 0.5 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) UcrQ PF02939.11 KZN84079.1 - 1.4e-26 92.0 0.1 1.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 KZN84079.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2741) Spermine_synth PF01564.12 KZN84080.1 - 1.5e-96 322.0 0.0 1.9e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 KZN84080.1 - 7.3e-05 22.3 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN84080.1 - 0.00013 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84080.1 - 0.00049 20.5 0.2 0.005 17.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KZN84080.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KZN84080.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84080.1 - 0.058 13.1 0.0 0.3 10.7 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KZN84080.1 - 0.081 13.4 0.0 0.26 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 KZN84080.1 - 0.13 11.4 0.4 0.49 9.5 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase Fungal_trans PF04082.13 KZN84081.1 - 7.4e-18 64.3 0.3 1.4e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84081.1 - 2.5e-11 43.2 7.3 4.8e-11 42.3 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.13 KZN84084.1 - 1.6e-24 86.5 0.0 2.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN84084.1 - 1.5e-10 41.3 0.1 6.1e-10 39.3 0.0 1.9 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KZN84084.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 KZN84084.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transketolase_N PF00456.16 KZN84085.1 - 1.6e-74 250.7 0.2 2.5e-74 250.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KZN84085.1 - 2.2e-45 154.3 0.0 3.9e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KZN84085.1 - 2e-13 50.3 0.0 4.8e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KZN84085.1 - 0.011 14.6 0.1 0.03 13.2 0.0 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KZN84085.1 - 0.023 13.3 0.1 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component FAD_binding_3 PF01494.14 KZN84086.1 - 9.3e-80 268.3 0.0 8.1e-57 192.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 KZN84086.1 - 2e-36 125.1 0.0 3.5e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KZN84086.1 - 3.5e-05 23.0 0.0 5.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KZN84086.1 - 5e-05 21.9 0.0 7.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KZN84086.1 - 7.7e-05 21.7 0.1 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN84086.1 - 0.00016 21.6 0.1 0.00051 19.9 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN84086.1 - 0.0014 18.5 0.0 0.03 14.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN84086.1 - 0.0039 16.1 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN84086.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN84086.1 - 0.0091 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KZN84086.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KZN84086.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2199 PF09965.4 KZN84086.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Lycopene_cycl PF05834.7 KZN84086.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.19 KZN84087.1 - 2.5e-137 458.1 24.0 2.9e-137 457.9 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84087.1 - 3.5e-32 111.4 50.8 2.6e-25 88.9 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 KZN84087.1 - 0.0074 16.2 1.6 0.44 10.5 0.0 3.6 3 1 0 3 3 3 1 Poxvirus virion envelope protein A14 DUF4064 PF13273.1 KZN84087.1 - 6.2 6.9 16.9 0.71 10.0 1.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) DUF3533 PF12051.3 KZN84088.1 - 1.2e-90 304.0 15.8 1.4e-90 303.8 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1129 PF06570.6 KZN84088.1 - 0.43 9.8 7.2 0.85 8.8 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Fungal_trans PF04082.13 KZN84089.1 - 1.4e-33 115.8 0.1 2.5e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84089.1 - 8.3e-09 35.2 14.7 1.4e-08 34.4 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 KZN84090.1 - 0.0026 18.1 0.0 0.0041 17.4 0.0 1.6 1 1 0 1 1 1 1 SET domain DUF3857 PF12969.2 KZN84090.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) MMR_HSR1_C PF08438.5 KZN84092.1 - 1e-31 109.3 0.0 1.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KZN84092.1 - 7.5e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AMP-binding PF00501.23 KZN84094.1 - 1.1e-70 238.1 0.0 1.9e-70 237.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KZN84094.1 - 4.1e-35 120.9 0.0 4.1e-25 88.1 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein AMP-binding_C PF13193.1 KZN84094.1 - 4.5e-12 46.7 0.1 1.4e-11 45.1 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KZN84094.1 - 5.2e-09 35.8 0.0 1e-05 25.1 0.0 3.0 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN84094.1 - 1.7e-07 31.3 0.1 3.9e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN84094.1 - 6.5e-05 21.7 0.0 0.048 12.3 0.0 3.0 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KZN84094.1 - 0.0002 21.6 0.0 0.00064 20.0 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KZN84094.1 - 0.00055 19.8 0.0 0.0022 17.9 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84094.1 - 0.039 13.6 0.1 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 KZN84094.1 - 0.097 12.6 0.5 0.85 9.6 0.1 2.6 3 0 0 3 3 3 0 NADH(P)-binding Aminotran_1_2 PF00155.16 KZN84095.1 - 2.3e-33 115.6 0.0 2.9e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KZN84095.1 - 0.00076 18.1 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 KZN84095.1 - 0.015 13.6 0.0 0.026 12.7 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF3834 PF12916.2 KZN84095.1 - 0.067 12.1 0.0 7.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) Ribosomal_L7Ae PF01248.21 KZN84098.1 - 1.1e-18 66.5 1.4 1.1e-18 66.5 1.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Topoisom_I_N PF02919.10 KZN84098.1 - 0.77 9.0 6.2 1.5 8.0 4.3 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment MAD PF05557.8 KZN84099.1 - 1.3e-52 178.8 70.4 1.1e-43 149.4 49.2 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein Flp_N PF03930.9 KZN84099.1 - 0.036 13.8 0.8 0.17 11.6 0.4 2.4 1 1 0 1 1 1 0 Recombinase Flp protein N-terminus DASH_Dam1 PF08653.5 KZN84099.1 - 4.3 7.1 10.2 7.1 6.4 0.0 4.5 4 1 1 5 5 5 0 DASH complex subunit Dam1 muHD PF10291.4 KZN84100.1 - 3.3e-79 265.7 0.0 4.7e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KZN84100.1 - 9.9e-11 41.6 0.0 3.5e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain COG2 PF06148.6 KZN84100.1 - 0.074 12.9 2.4 0.14 11.9 0.3 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 KZN84101.1 - 3.4e-45 154.2 0.0 4.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84101.1 - 2.5e-16 59.5 0.0 3.7e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN84101.1 - 3.6e-08 33.4 0.8 0.00033 20.4 0.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN84101.1 - 0.00025 20.1 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN84101.1 - 0.017 14.1 0.0 0.046 12.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KZN84101.1 - 0.066 12.5 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SH3_9 PF14604.1 KZN84102.1 - 7.2e-08 31.9 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN84102.1 - 1.4e-05 24.3 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KZN84102.1 - 0.00025 20.4 0.0 0.00055 19.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Syndecan PF01034.15 KZN84102.1 - 0.0034 16.9 0.1 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KZN84102.1 - 0.0063 15.8 3.2 0.017 14.4 2.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 KZN84102.1 - 0.0083 15.8 0.1 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family Plasmodium_Vir PF05795.6 KZN84102.1 - 2.9 7.0 4.6 5.6 6.0 3.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tim54 PF11711.3 KZN84102.1 - 4.2 5.8 7.6 6.2 5.3 5.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ank_4 PF13637.1 KZN84104.1 - 8.3e-21 73.9 0.4 4.4e-10 39.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN84104.1 - 1.4e-18 66.9 0.0 3.5e-12 46.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84104.1 - 7.2e-18 63.4 0.9 3.8e-06 26.4 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KZN84104.1 - 2.4e-13 49.8 0.7 3.1e-09 36.7 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN84104.1 - 9.6e-13 47.0 0.0 0.0015 18.5 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeat DUF2384 PF09722.5 KZN84104.1 - 0.26 11.1 1.2 1e+02 2.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) Sugar_tr PF00083.19 KZN84105.1 - 6.1e-105 351.3 15.9 7.6e-105 351.0 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84105.1 - 1.9e-17 63.0 28.2 9.8e-15 54.1 1.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KZN84105.1 - 2.3e-05 22.6 1.2 4.6e-05 21.6 0.8 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TPR_19 PF14559.1 KZN84105.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF605 PF04652.11 KZN84107.1 - 7.9 5.7 22.9 10 5.3 15.8 1.1 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 KZN84108.1 - 5.5e-38 130.5 28.9 5.5e-38 130.5 20.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84108.1 - 4.3e-13 48.6 11.4 4.3e-13 48.6 7.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KZN84108.1 - 0.0061 14.7 3.2 0.0093 14.1 2.2 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OPT PF03169.10 KZN84109.1 - 1.6e-175 585.1 10.9 1.8e-175 584.9 7.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 KZN84109.1 - 0.11 12.4 7.9 3.7 7.6 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) ERG4_ERG24 PF01222.12 KZN84110.1 - 3.2e-135 451.0 21.4 3.9e-135 450.7 14.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UAA PF08449.6 KZN84110.1 - 0.038 12.8 3.2 0.061 12.2 0.6 2.1 2 0 0 2 2 2 0 UAA transporter family Acetyltransf_1 PF00583.19 KZN84111.1 - 2.3e-05 24.3 0.4 4.2e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KZN84111.1 - 0.0045 16.8 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KZN84111.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN84111.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TPP_enzyme_N PF02776.13 KZN84112.1 - 1.6e-22 79.7 0.3 3.3e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN84112.1 - 1.6e-11 44.1 0.0 7.5e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ArsD PF06953.6 KZN84112.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD 4HBT_2 PF13279.1 KZN84113.1 - 2.4e-09 37.6 0.0 3.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily JmjC PF02373.17 KZN84114.1 - 4.6e-38 129.9 2.2 6.8e-38 129.4 0.4 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KZN84114.1 - 1.4e-17 63.6 3.4 2.6e-17 62.8 2.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KZN84114.1 - 1.4e-16 60.4 4.0 2.9e-16 59.3 2.8 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 KZN84114.1 - 1.6e-16 59.4 0.5 3.9e-16 58.2 0.3 1.7 1 0 0 1 1 1 1 jmjN domain AA_permease_2 PF13520.1 KZN84115.1 - 5.4e-57 193.2 53.2 6.5e-57 192.9 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84115.1 - 7.6e-33 113.5 48.7 1e-32 113.1 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease ACBP PF00887.14 KZN84116.1 - 1.9e-26 91.5 0.0 3.9e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein HSP90 PF00183.13 KZN84116.1 - 0.26 9.6 4.0 0.38 9.0 2.7 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 KZN84116.1 - 1.8 6.4 14.6 2.6 5.9 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_71 PF03659.9 KZN84117.1 - 1.1e-150 501.4 3.2 1.6e-150 500.9 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CHCH PF06747.8 KZN84118.1 - 6.2e-07 29.1 6.5 6.2e-07 29.1 4.5 2.6 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 KZN84118.1 - 0.08 12.9 10.6 6.8 6.8 6.3 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KZN84118.1 - 2.5 7.9 14.6 2.8 7.7 3.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 KZN84118.1 - 3.4 7.7 11.1 4.6 7.3 0.5 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Nup54 PF13874.1 KZN84119.1 - 1.1e-44 151.5 1.9 4.6e-44 149.4 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KZN84119.1 - 7.8e-13 48.6 126.9 8.6e-08 32.4 28.3 2.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region Fib_alpha PF08702.5 KZN84119.1 - 0.0013 18.9 1.7 0.0033 17.5 1.2 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family EzrA PF06160.7 KZN84119.1 - 0.0064 14.7 7.0 0.057 11.6 1.7 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA ApoLp-III PF07464.6 KZN84119.1 - 0.0066 16.4 3.3 0.015 15.3 2.3 1.6 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF3867 PF12983.2 KZN84119.1 - 0.048 13.6 2.8 0.13 12.2 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) V-SNARE_C PF12352.3 KZN84119.1 - 0.058 13.4 1.9 5.6 7.1 0.1 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF948 PF06103.6 KZN84119.1 - 0.12 12.2 0.2 0.8 9.6 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.8 KZN84119.1 - 0.21 11.0 4.2 0.42 10.1 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.1 KZN84119.1 - 0.36 11.1 6.6 13 6.1 0.1 3.2 2 1 1 3 3 3 0 Snapin/Pallidin DUF4164 PF13747.1 KZN84119.1 - 0.92 9.6 5.9 1.1 9.4 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Tup_N PF08581.5 KZN84119.1 - 1.9 8.7 8.6 0.16 12.1 1.5 2.4 3 0 0 3 3 2 0 Tup N-terminal DUF1664 PF07889.7 KZN84119.1 - 2.4 7.9 5.7 2.2 8.0 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Gly-zipper_OmpA PF13436.1 KZN84119.1 - 3.2 7.4 14.1 3.8 7.2 2.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Occludin_ELL PF07303.8 KZN84119.1 - 4.2 8.1 6.4 15 6.3 1.5 2.9 2 2 0 2 2 2 0 Occludin homology domain Prefoldin PF02996.12 KZN84119.1 - 5.8 6.5 7.8 4 7.0 0.8 2.8 1 1 0 2 2 2 0 Prefoldin subunit Tom5 PF10642.4 KZN84120.1 - 5.5e-20 70.7 0.3 5.9e-20 70.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 KZN84121.1 - 4.6e-13 48.4 0.3 8.5e-13 47.5 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HIG_1_N PF04588.8 KZN84122.1 - 1.7e-06 27.6 0.7 1.7e-06 27.6 0.5 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Innate_immun PF12782.2 KZN84122.1 - 0.015 14.5 0.5 0.028 13.6 0.3 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DASH_Ask1 PF08655.5 KZN84123.1 - 2.3e-32 110.6 0.1 5.1e-32 109.5 0.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 Pkinase PF00069.20 KZN84125.1 - 4.6e-54 183.2 0.0 6.2e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84125.1 - 4.4e-22 78.4 0.0 6.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84125.1 - 0.00059 18.8 0.0 0.00088 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KZN84125.1 - 0.007 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KZN84125.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN84125.1 - 0.019 14.6 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thiolase_N PF00108.18 KZN84128.1 - 5.8e-71 238.5 0.1 9.5e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN84128.1 - 2.9e-41 139.7 1.7 3.6e-41 139.4 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KZN84128.1 - 0.012 15.1 1.3 0.031 13.7 0.9 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KZN84128.1 - 0.043 13.4 0.0 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WLM PF08325.5 KZN84129.1 - 1.1e-46 159.0 0.1 9.9e-46 155.9 0.0 2.2 3 0 0 3 3 3 1 WLM domain SprT-like PF10263.4 KZN84129.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 KZN84129.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 KZN84129.1 - 0.033 14.2 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Zn_clus PF00172.13 KZN84130.1 - 3.2e-10 39.7 10.7 5.8e-10 38.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.5 KZN84130.1 - 0.71 9.8 5.0 2.1 8.3 3.4 1.8 1 0 0 1 1 1 0 BCMA, TALL-1 binding Sugar_tr PF00083.19 KZN84131.1 - 2.7e-115 385.5 22.4 3.1e-115 385.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84131.1 - 1.3e-27 96.4 26.4 2.8e-20 72.3 2.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 KZN84132.1 - 1.5e-58 197.5 2.1 1.7e-58 197.3 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN84132.1 - 4.9e-42 143.4 9.8 4.9e-42 143.4 6.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN84132.1 - 1.4e-27 97.5 0.0 3.4e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN84132.1 - 9.5e-15 54.3 0.0 1.9e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN84132.1 - 5.2e-14 52.8 0.0 3e-13 50.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN84132.1 - 3.2e-08 32.9 0.0 1.7e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN84132.1 - 0.00029 20.4 0.2 0.0013 18.3 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IBR PF01485.16 KZN84133.1 - 6.6e-13 48.3 45.3 5e-06 26.2 10.1 4.4 4 0 0 4 4 4 4 IBR domain zf-C3HC4 PF00097.20 KZN84133.1 - 0.001 18.6 3.4 0.001 18.6 2.4 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN84133.1 - 0.0097 15.7 5.1 0.0097 15.7 3.5 4.6 3 1 2 5 5 5 1 Ring finger domain M_domain PF12938.2 KZN84133.1 - 0.29 10.8 0.9 1 9.1 0.6 1.7 1 1 1 2 2 2 0 M domain of GW182 HSP70 PF00012.15 KZN84134.1 - 9.5e-160 532.4 1.6 9.5e-160 532.4 1.1 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KZN84134.1 - 4.4e-11 41.9 0.0 4.5e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KZN84134.1 - 2.2e-05 24.2 0.4 0.097 12.5 0.1 3.2 2 1 0 2 2 2 2 Cell division protein FtsA Imm26 PF15572.1 KZN84134.1 - 0.042 13.9 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 26 Chitin_synth_2 PF03142.10 KZN84135.1 - 1.5e-23 83.0 0.8 1.5e-23 83.0 0.6 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KZN84135.1 - 1e-15 57.9 7.6 1e-15 57.9 5.3 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN84135.1 - 1.7e-15 57.4 0.0 2.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 La PF05383.12 KZN84136.1 - 7.9e-19 67.2 0.0 1.3e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KZN84136.1 - 1.1e-08 34.5 0.1 2.6e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84136.1 - 3.4e-06 26.9 0.0 7.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84136.1 - 0.006 16.4 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 KZN84136.1 - 0.011 14.2 3.5 0.023 13.2 2.4 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Dabb PF07876.7 KZN84137.1 - 9e-18 64.5 0.0 1e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain AAA_12 PF13087.1 KZN84138.1 - 1e-37 129.4 0.0 2.2e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN84138.1 - 2.7e-28 99.1 0.0 5.9e-28 98.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN84138.1 - 9.8e-10 38.0 0.0 3.1e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KZN84138.1 - 8.9e-08 31.9 0.0 0.0032 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KZN84138.1 - 0.00021 20.8 0.1 0.27 10.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KZN84138.1 - 0.00028 20.3 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KZN84138.1 - 0.00084 18.6 0.0 0.089 12.0 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein UvrD_C_2 PF13538.1 KZN84138.1 - 0.0015 18.6 0.1 0.28 11.3 0.0 3.0 3 0 0 3 3 2 1 UvrD-like helicase C-terminal domain AAA_18 PF13238.1 KZN84138.1 - 0.0044 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN84138.1 - 0.0076 17.0 0.2 0.03 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN84138.1 - 0.0084 16.1 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KZN84138.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KZN84138.1 - 0.036 13.0 0.3 0.19 10.6 0.0 2.4 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 KZN84138.1 - 0.062 13.0 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KZN84138.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PBP1_TM PF14812.1 KZN84138.1 - 0.21 11.9 7.3 0.86 9.9 5.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sulfatase PF00884.18 KZN84139.1 - 2.9e-21 75.9 0.6 5.8e-21 74.9 0.4 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN84139.1 - 5.2e-05 22.7 0.3 9.1e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4059 PF13268.1 KZN84139.1 - 0.008 16.3 0.6 0.21 11.8 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4059) DUF229 PF02995.12 KZN84139.1 - 0.076 11.4 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) EFP PF01132.15 KZN84139.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain APH PF01636.18 KZN84140.1 - 1.2e-12 48.0 0.0 9.6e-12 45.1 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN84140.1 - 0.011 15.3 1.0 0.074 12.6 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase SUI1 PF01253.17 KZN84141.1 - 2.5e-17 62.4 0.1 5.3e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 KZN84141.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein TIR_2 PF13676.1 KZN84143.1 - 0.14 12.2 0.6 0.21 11.7 0.1 1.5 2 0 0 2 2 2 0 TIR domain Glyco_hydro_61 PF03443.9 KZN84144.1 - 7.9e-84 280.8 0.3 7.9e-84 280.8 0.2 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 TIG PF01833.19 KZN84145.1 - 6e-12 45.3 0.2 1.9e-11 43.8 0.2 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 KZN84145.1 - 5e-10 39.5 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84145.1 - 3.3e-09 36.0 2.9 0.001 18.7 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KZN84145.1 - 4.6e-08 33.0 2.0 3.4e-06 27.0 0.9 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN84145.1 - 7.1e-07 29.5 1.2 7.2e-06 26.3 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN84145.1 - 3.2e-06 26.8 0.7 0.12 12.6 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Aminotran_3 PF00202.16 KZN84146.1 - 1.3e-54 185.3 0.0 2.6e-54 184.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III MBOAT_2 PF13813.1 KZN84147.1 - 9.3e-25 86.5 0.0 2.8e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TRAPPC10 PF12584.3 KZN84148.1 - 4.2e-39 133.3 0.0 1.1e-38 132.0 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KZN84148.1 - 0.006 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 FA_desaturase PF00487.19 KZN84149.1 - 1.8e-24 86.6 15.8 3e-24 85.8 11.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KZN84149.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.6 KZN84150.1 - 1.3e-24 86.5 0.0 2.7e-24 85.4 0.0 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 KZN84150.1 - 1.2e-15 57.4 0.0 2.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KZN84150.1 - 7.5e-08 31.7 0.0 2.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.16 KZN84150.1 - 1.9e-06 27.1 0.0 4.6e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 recA bacterial DNA recombination protein NACHT PF05729.7 KZN84150.1 - 0.0041 16.7 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DnaB_C PF03796.10 KZN84150.1 - 0.012 14.5 0.2 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KZN84150.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KZN84150.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Phage_1_1 PF08200.6 KZN84151.1 - 0.032 14.4 0.7 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein Velvet PF11754.3 KZN84152.1 - 7.8e-63 211.7 0.0 1.4e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Velvet factor MFS_1 PF07690.11 KZN84154.1 - 3.2e-19 68.8 54.6 8.1e-13 47.7 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KZN84154.1 - 0.11 12.5 9.7 1.7 8.6 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) Cyclase PF04199.8 KZN84155.1 - 6.9e-14 51.8 0.1 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase LSM14 PF12701.2 KZN84156.1 - 1.5e-31 108.0 0.0 2.8e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KZN84156.1 - 1.8e-19 70.1 1.5 3.6e-19 69.2 1.0 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 KZN84156.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain WD40 PF00400.27 KZN84157.1 - 3.5e-28 96.4 2.0 8e-05 22.3 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KZN84157.1 - 0.0013 18.2 1.2 0.073 12.5 0.6 2.8 1 1 2 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 KZN84157.1 - 0.0042 17.3 0.1 6.8 7.1 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain Reg_prop PF07494.6 KZN84157.1 - 0.0043 16.9 0.0 0.45 10.7 0.0 2.9 2 0 0 2 2 2 1 Two component regulator propeller Nup160 PF11715.3 KZN84157.1 - 0.012 13.7 0.1 0.061 11.4 0.1 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Sigma70_r1_2 PF00140.15 KZN84157.1 - 0.1 12.3 0.9 0.28 10.8 0.6 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Thioredox_DsbH PF03190.10 KZN84158.1 - 1e-70 236.6 0.1 1.6e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KZN84158.1 - 2e-08 34.1 0.0 4.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 KZN84158.1 - 0.012 14.8 0.5 5.4 6.2 0.2 2.9 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Thioredoxin_2 PF13098.1 KZN84158.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_47 PF01532.15 KZN84158.1 - 0.056 12.0 0.1 0.099 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 CAP PF00188.21 KZN84159.1 - 3.6e-18 66.2 2.2 3.6e-18 66.2 1.5 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TFIIA PF03153.8 KZN84159.1 - 3.9 7.2 7.9 4.7 7.0 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3359 PF11839.3 KZN84159.1 - 4.1 7.7 10.6 0.24 11.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3359) Carn_acyltransf PF00755.15 KZN84160.1 - 1.8e-166 554.7 0.0 1.4e-150 502.2 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.14 KZN84160.1 - 7.9e-35 119.7 0.3 2.4e-16 59.6 0.1 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 KZN84160.1 - 1.3e-17 64.0 0.1 3.2e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 KZN84160.1 - 1.7e-09 37.3 0.0 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KZN84160.1 - 0.0037 17.4 0.1 0.011 15.8 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KZN84160.1 - 0.2 10.9 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RTA1 PF04479.8 KZN84161.1 - 5.7e-40 137.2 2.8 6.9e-40 136.9 2.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DAG1 PF05454.6 KZN84161.1 - 0.11 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RicinB_lectin_2 PF14200.1 KZN84162.1 - 8e-06 26.1 0.0 0.014 15.7 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rad60-SLD PF11976.3 KZN84164.1 - 6.7e-21 73.7 0.3 8.3e-21 73.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KZN84164.1 - 2.5e-08 33.2 0.1 3.1e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 KZN84164.1 - 0.025 14.2 0.1 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 KZN84165.1 - 3.8e-59 200.0 0.0 5.2e-58 196.3 0.0 2.6 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 RRN3 PF05327.6 KZN84165.1 - 4.7 5.1 11.3 7.7 4.4 7.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 E1-E2_ATPase PF00122.15 KZN84166.1 - 1.4e-64 217.2 3.0 1.9e-64 216.8 0.8 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN84166.1 - 1.3e-44 151.8 7.6 1.3e-44 151.8 5.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN84166.1 - 3.6e-27 96.1 0.6 4.1e-26 92.7 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN84166.1 - 8.4e-18 64.1 0.0 1.7e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN84166.1 - 2.9e-13 50.4 0.0 8e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN84166.1 - 1.1e-08 34.4 0.1 3.6e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN84166.1 - 3.2e-05 23.6 2.4 0.00029 20.5 1.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PepSY_TM_3 PF13706.1 KZN84166.1 - 3.3 7.1 6.9 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix APH PF01636.18 KZN84167.1 - 1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN84167.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KZN84167.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase PAN_4 PF14295.1 KZN84169.1 - 0.00035 20.2 18.2 0.029 14.0 0.9 3.1 3 0 0 3 3 3 2 PAN domain MANEC PF07502.9 KZN84169.1 - 0.012 15.5 2.0 1.2 9.2 0.5 2.5 2 0 0 2 2 2 0 MANEC domain D-ser_dehydrat PF14031.1 KZN84170.1 - 1.8e-22 79.2 0.1 4.3e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KZN84170.1 - 1.7e-12 47.3 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain adh_short PF00106.20 KZN84171.1 - 7e-23 81.3 1.2 1e-22 80.8 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84171.1 - 4.9e-19 69.0 0.2 7.2e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN84171.1 - 1.2e-05 24.9 0.2 2.7e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN84171.1 - 4.6e-05 23.1 0.5 7e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN84171.1 - 0.00025 21.0 0.1 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN84171.1 - 0.00029 19.8 0.0 0.00039 19.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 KZN84171.1 - 0.0003 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KZN84171.1 - 0.089 12.5 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Transp_cyt_pur PF02133.10 KZN84174.1 - 1.1e-17 63.7 41.6 2.1e-17 62.8 28.8 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.4 KZN84175.1 - 1.9e-11 43.7 0.2 1.1e-10 41.2 0.2 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Tubulin PF00091.20 KZN84176.1 - 3e-69 233.1 0.0 5.2e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KZN84176.1 - 6.8e-49 165.0 0.0 1.2e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KZN84176.1 - 1e-05 25.5 0.0 2.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KZN84176.1 - 0.0044 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 KZN84177.1 - 1.5e-13 50.1 0.0 3.6e-05 23.3 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84177.1 - 1.3e-07 31.3 0.0 1.8e-05 24.4 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84177.1 - 1e-06 28.5 0.0 0.00052 19.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AIF-MLS PF14962.1 KZN84177.1 - 0.46 10.1 4.5 0.98 9.0 3.1 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Ammonium_transp PF00909.16 KZN84178.1 - 2.2e-123 411.7 31.0 2.5e-123 411.5 21.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 KZN84180.1 - 8.2e-67 225.0 0.0 1.3e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84180.1 - 1.7e-36 125.6 0.0 6.6e-36 123.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84180.1 - 1.8e-06 27.1 0.1 1.5e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KZN84180.1 - 0.0027 17.4 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN84180.1 - 0.0079 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KZN84180.1 - 0.042 12.9 0.4 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pirin PF02678.11 KZN84181.1 - 2.3e-24 85.3 0.9 9.9e-24 83.2 0.6 1.9 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KZN84181.1 - 4.3e-07 29.3 1.3 2.8e-05 23.5 0.1 3.5 3 2 0 3 3 3 1 Cupin domain Vac_ImportDeg PF09783.4 KZN84182.1 - 2.2e-71 238.9 1.3 2.9e-71 238.6 0.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 KZN84183.1 - 2.5e-76 254.2 0.6 2.8e-76 254.0 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 KZN84184.1 - 2.9e-91 306.3 10.2 4.8e-91 305.6 7.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KZN84184.1 - 4.1e-62 207.6 0.1 1.6e-61 205.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KZN84184.1 - 5.6e-62 207.5 0.8 1.3e-61 206.4 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KZN84184.1 - 9.2e-13 48.2 9.7 4.7e-08 33.1 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KZN84184.1 - 7.8e-05 22.5 9.9 0.0013 18.6 0.1 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KZN84184.1 - 9.7e-05 22.1 0.7 0.18 12.0 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KZN84184.1 - 0.00015 22.1 2.8 0.012 16.0 0.0 4.8 3 1 2 5 5 5 2 HEAT-like repeat AP4E_app_platf PF14807.1 KZN84184.1 - 0.03 14.5 0.1 0.15 12.2 0.1 2.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 KZN84184.1 - 0.038 13.8 2.0 0.44 10.4 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.19 KZN84185.1 - 8.8e-23 80.1 0.0 1.7e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 KZN84186.1 - 6.2e-45 153.2 0.0 2.5e-37 128.4 0.2 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 NOT2_3_5 PF04153.13 KZN84186.1 - 0.05 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DUF1730 PF08331.5 KZN84186.1 - 0.092 12.4 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) HATPase_c PF02518.21 KZN84187.1 - 1.4e-22 79.5 0.1 2.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN84187.1 - 1.4e-19 70.0 0.8 2.6e-19 69.2 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KZN84187.1 - 2.4e-13 49.8 0.0 1.3e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KZN84187.1 - 0.069 13.2 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 GAF domain Rad60-SLD PF11976.3 KZN84188.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1604 PF07713.8 KZN84189.1 - 3.2e-38 129.3 2.3 3.2e-38 129.3 1.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KZN84189.1 - 8e-07 28.7 3.6 2.5e-06 27.1 1.6 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KZN84189.1 - 0.011 15.5 0.5 0.011 15.5 0.4 3.2 3 1 0 3 3 3 0 DExH-box splicing factor binding site Glyco_transf_90 PF05686.7 KZN84190.1 - 9.3e-15 54.2 4.6 1e-05 24.4 1.0 4.1 3 1 0 3 3 3 3 Glycosyl transferase family 90 EABR PF12180.3 KZN84190.1 - 0.049 12.9 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 APH PF01636.18 KZN84191.1 - 9.1e-05 22.3 0.0 0.00033 20.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN84191.1 - 0.0037 16.2 0.0 0.0064 15.4 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.20 KZN84192.1 - 5.2e-23 81.5 0.0 9.3e-23 80.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84192.1 - 0.0058 15.7 0.0 0.18 10.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_16 PF00722.16 KZN84193.1 - 7.4e-40 136.2 4.6 7.4e-40 136.2 3.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KZN84194.1 - 2.8e-36 124.9 10.5 2.8e-36 124.9 7.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84194.1 - 1.2e-06 27.4 9.5 1.2e-06 27.4 6.6 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.15 KZN84194.1 - 1.9 7.7 6.6 11 5.2 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 PhaG_MnhG_YufB PF03334.9 KZN84194.1 - 7.2 6.7 10.5 6.8 6.8 0.8 4.0 3 1 0 3 3 3 0 Na+/H+ antiporter subunit Amino_oxidase PF01593.19 KZN84195.1 - 2.5e-45 155.3 0.1 2.4e-41 142.2 0.0 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN84195.1 - 4.9e-15 55.3 0.3 8.7e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN84195.1 - 4.9e-09 36.4 0.6 9.2e-08 32.3 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN84195.1 - 6.8e-07 28.1 0.6 1.3e-06 27.1 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KZN84195.1 - 2.6e-06 26.5 0.0 4.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN84195.1 - 3.7e-06 27.1 0.3 1.6e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN84195.1 - 9e-06 24.9 0.2 2e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KZN84195.1 - 1.1e-05 25.0 0.1 2.1e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KZN84195.1 - 1.2e-05 24.5 0.5 2.2e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KZN84195.1 - 5.9e-05 22.3 0.5 5.9e-05 22.3 0.4 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN84195.1 - 9.6e-05 21.3 1.9 0.00016 20.6 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KZN84195.1 - 0.00025 20.0 0.5 0.57 9.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KZN84195.1 - 0.00087 18.2 2.6 0.0019 17.1 1.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KZN84195.1 - 0.0022 17.9 0.1 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KZN84195.1 - 0.0038 16.9 0.2 0.0069 16.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KZN84195.1 - 0.0082 16.2 0.3 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 KZN84195.1 - 0.025 12.7 0.0 0.034 12.3 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 KZN84195.1 - 0.063 13.5 0.7 0.51 10.6 0.0 2.4 3 0 0 3 3 3 0 Putative NAD(P)-binding YjeF_N PF03853.10 KZN84195.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus UPF0146 PF03686.8 KZN84195.1 - 0.17 11.6 0.3 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Lycopene_cycl PF05834.7 KZN84195.1 - 0.2 10.5 0.4 0.31 9.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AA_permease PF00324.16 KZN84196.1 - 1.1e-99 334.0 50.8 1.3e-99 333.7 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN84196.1 - 7.2e-28 97.2 51.7 9.9e-28 96.8 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_C PF05199.8 KZN84197.1 - 2.4e-30 105.6 0.1 3.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KZN84197.1 - 6.1e-30 104.3 0.0 1.9e-26 92.8 0.0 2.9 1 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN84197.1 - 0.0023 17.9 0.5 0.0079 16.2 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN84197.1 - 0.0086 14.9 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN84197.1 - 0.019 14.8 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN84197.1 - 0.025 13.5 0.1 0.72 8.6 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KZN84197.1 - 0.092 12.1 0.6 0.19 11.1 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KZN84197.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3431 PF11913.3 KZN84199.1 - 2.6e-72 242.9 0.0 3.3e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) NAD_binding_10 PF13460.1 KZN84200.1 - 9.4e-13 48.5 0.4 1.5e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN84200.1 - 8.2e-10 38.3 0.0 1.6e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 KZN84200.1 - 6.3e-07 28.7 0.0 8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KZN84200.1 - 0.00012 22.0 0.1 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KZN84200.1 - 0.0011 18.4 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN84200.1 - 0.0019 17.8 0.2 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KZN84200.1 - 0.0024 18.1 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KZN84200.1 - 0.042 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain HicB PF05534.7 KZN84200.1 - 0.043 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 HicB family DapB_N PF01113.15 KZN84200.1 - 0.045 13.6 0.1 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KZN84200.1 - 0.049 14.0 0.1 0.099 13.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EI24 PF07264.6 KZN84201.1 - 0.00029 20.3 3.6 0.00069 19.1 2.5 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FSH1 PF03959.8 KZN84202.1 - 6.8e-41 140.0 0.0 9.1e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KZN84202.1 - 0.0002 21.1 0.0 0.00034 20.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN84202.1 - 0.0026 17.6 0.0 0.69 9.7 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 KZN84203.1 - 1.8e-09 37.5 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KZN84203.1 - 8.9e-09 35.4 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN84203.1 - 3.4e-08 33.5 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN84203.1 - 5.5e-07 29.7 0.1 6.8e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN84203.1 - 0.0095 15.7 0.1 0.026 14.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN84203.1 - 0.15 11.9 0.0 0.45 10.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.1 KZN84204.1 - 2e-10 40.9 0.1 3.3e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN84204.1 - 1.6e-06 27.6 0.0 5e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KZN84204.1 - 0.00052 19.5 0.0 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN84204.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KZN84204.1 - 0.032 14.1 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HIM1 PF08732.5 KZN84204.1 - 0.097 11.1 0.0 0.19 10.1 0.0 1.3 1 1 0 1 1 1 0 HIM1 Glyco_transf_90 PF05686.7 KZN84205.1 - 2.7e-14 52.6 0.8 8e-10 37.9 0.0 3.1 3 0 0 3 3 3 3 Glycosyl transferase family 90 ImpA-rel_N PF06812.7 KZN84205.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 ImpA-related N-terminal CRAL_TRIO PF00650.15 KZN84206.1 - 2.3e-25 88.9 0.0 4.7e-25 87.9 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN84206.1 - 1.9e-05 24.6 0.0 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain TPR_7 PF13176.1 KZN84208.1 - 3.8e-06 26.2 4.2 1.1 9.1 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN84208.1 - 4.6e-06 26.4 13.1 0.0002 21.2 1.4 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN84208.1 - 5.3e-06 25.9 14.4 0.00011 21.8 0.5 4.5 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KZN84208.1 - 6.4e-06 26.7 5.0 0.027 15.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84208.1 - 0.00011 22.4 13.1 0.058 14.0 0.0 6.3 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN84208.1 - 0.00067 19.9 9.9 0.00082 19.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 KZN84208.1 - 0.0011 18.7 0.1 0.0044 16.7 0.0 2.1 1 1 0 1 1 1 1 NACHT domain PerB PF06590.6 KZN84208.1 - 0.056 13.7 0.2 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 PerB protein DUF3366 PF11846.3 KZN84208.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) TPR_1 PF00515.23 KZN84208.1 - 0.17 11.5 10.7 1.3 8.7 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-LSD1 PF06943.7 KZN84208.1 - 0.17 11.5 0.5 6.5 6.4 0.3 2.5 2 0 0 2 2 2 0 LSD1 zinc finger TPR_6 PF13174.1 KZN84208.1 - 0.18 12.3 11.7 1.6 9.3 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN84208.1 - 0.48 10.4 17.2 1.1 9.3 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84208.1 - 0.7 9.8 7.1 8.6 6.4 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Response_reg PF00072.19 KZN84210.1 - 8.2e-21 74.1 0.3 2.6e-19 69.2 0.4 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KZN84210.1 - 2.1e-19 69.2 0.1 4.9e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KZN84210.1 - 4.4e-12 45.8 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KZN84210.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dynein_light PF01221.13 KZN84210.1 - 0.094 12.7 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Dynein light chain type 1 Acyl_transf_3 PF01757.17 KZN84211.1 - 5.4e-18 64.9 29.7 1.3e-17 63.6 20.6 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF3579 PF12112.3 KZN84211.1 - 0.016 15.1 0.0 0.061 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) RabGAP-TBC PF00566.13 KZN84212.1 - 2e-39 135.2 0.0 9.9e-39 133.0 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Choline_transpo PF04515.7 KZN84213.1 - 1.2e-106 356.3 23.7 1.2e-106 356.3 16.4 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 KZN84213.1 - 0.028 14.4 2.5 0.079 13.0 1.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CFEM PF05730.6 KZN84214.1 - 1.5 8.6 10.4 1.8 8.4 4.3 2.2 2 0 0 2 2 2 0 CFEM domain ABM PF03992.11 KZN84216.1 - 0.00088 19.2 0.1 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.9 KZN84216.1 - 0.023 14.0 0.3 0.026 13.9 0.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF482 PF04339.7 KZN84216.1 - 0.06 12.2 0.2 0.066 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF482 DUF188 PF02639.9 KZN84216.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 BCS1_N PF08740.6 KZN84217.1 - 2.8e-53 180.3 0.2 3.7e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KZN84217.1 - 2.9e-18 66.3 0.0 5.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN84217.1 - 5e-05 24.1 0.0 0.00011 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN84217.1 - 0.00018 21.7 0.0 0.00048 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KZN84217.1 - 0.00058 19.8 0.2 0.0022 18.0 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KZN84217.1 - 0.00065 18.7 0.0 0.001 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KZN84217.1 - 0.00089 18.7 0.0 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN84217.1 - 0.0019 18.3 0.0 0.0084 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KZN84217.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KZN84217.1 - 0.0068 16.5 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.9 KZN84217.1 - 0.0068 16.1 0.0 0.024 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KZN84217.1 - 0.0074 16.1 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KZN84217.1 - 0.016 14.7 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KZN84217.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF2735 PF10931.3 KZN84217.1 - 0.03 14.5 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) AAA_24 PF13479.1 KZN84217.1 - 0.041 13.4 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN84217.1 - 0.048 13.4 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 KZN84217.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 KZN84217.1 - 0.066 12.3 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KZN84217.1 - 0.085 12.8 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KZN84217.1 - 0.091 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KZN84217.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.1 KZN84217.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KZN84218.1 - 3e-41 141.1 0.1 4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN84218.1 - 8.6e-11 41.8 0.0 3e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KZN84218.1 - 0.0023 17.6 3.0 0.081 12.5 1.0 2.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.19 KZN84219.1 - 1.6e-164 548.0 0.1 1.9e-164 547.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 KZN84220.1 - 6.1e-43 145.7 9.0 8.9e-43 145.2 6.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNase_H2-Ydr279 PF09468.5 KZN84220.1 - 0.28 10.3 6.3 0.35 10.0 4.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 KZN84220.1 - 0.6 9.8 4.9 0.9 9.3 3.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 KZN84220.1 - 2 6.3 7.3 2.4 6.0 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 KZN84220.1 - 2.4 8.1 7.5 4.9 7.1 5.2 1.6 1 0 0 1 1 1 0 YqfQ-like protein Med19 PF10278.4 KZN84220.1 - 4.1 7.0 12.8 6.3 6.4 8.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 zf-PARP PF00645.13 KZN84221.1 - 6.4e-22 77.5 0.1 1.5e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Pecanex_C PF05041.10 KZN84221.1 - 0.039 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) AT_hook PF02178.14 KZN84221.1 - 0.059 13.0 16.0 0.038 13.6 2.3 3.8 2 0 0 2 2 2 0 AT hook motif DUF605 PF04652.11 KZN84222.1 - 2.6 7.3 14.9 3.7 6.8 10.3 1.1 1 0 0 1 1 1 0 Vta1 like CENP-B_dimeris PF09026.5 KZN84222.1 - 5.6 7.2 8.9 11 6.2 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB PF00651.26 KZN84223.1 - 2.7e-07 30.5 0.0 1.9e-06 27.8 0.0 2.3 3 0 0 3 3 3 1 BTB/POZ domain Lipase_3 PF01764.20 KZN84224.1 - 6.6e-23 80.8 0.0 9e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) MU117 PF15474.1 KZN84225.1 - 1.5e-24 86.2 5.2 3.9e-24 84.9 3.6 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene family F-box-like PF12937.2 KZN84227.1 - 0.0051 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KZN84227.1 - 0.67 9.6 8.6 15 5.2 0.2 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Abhydrolase_6 PF12697.2 KZN84229.1 - 1.9e-12 47.5 0.5 3.3e-12 46.7 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84229.1 - 3.7e-11 42.9 0.4 9e-11 41.7 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN84229.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KZN84229.1 - 0.001 18.6 0.1 0.0024 17.4 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KZN84229.1 - 0.007 15.8 0.1 0.14 11.5 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KZN84229.1 - 0.014 14.5 0.1 0.063 12.4 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 KZN84229.1 - 0.031 12.7 0.0 0.066 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KZN84229.1 - 0.037 13.8 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF218 PF02698.12 KZN84229.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 DUF218 domain DUF2752 PF10825.3 KZN84230.1 - 0.076 13.0 3.4 0.12 12.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Adaptin_binding PF10199.4 KZN84230.1 - 6.9 6.9 12.1 23 5.2 8.4 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 F-box-like PF12937.2 KZN84231.1 - 8.6e-06 25.3 0.3 0.00037 20.1 0.2 2.4 2 0 0 2 2 2 2 F-box-like Epimerase PF01370.16 KZN84235.1 - 1.8e-42 145.4 0.1 2.1e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN84235.1 - 1.8e-14 53.1 0.0 2.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN84235.1 - 3e-14 52.6 0.0 6.2e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KZN84235.1 - 0.0004 19.3 0.1 0.0016 17.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KZN84235.1 - 0.0029 17.5 0.1 0.023 14.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN84235.1 - 0.0091 14.9 0.1 0.063 12.1 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN84235.1 - 0.011 15.7 0.1 0.051 13.5 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Pkinase PF00069.20 KZN84236.1 - 9.7e-10 38.0 0.0 3e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84236.1 - 7.9e-08 31.6 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84236.1 - 0.023 13.6 0.0 0.053 12.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like DUF4551 PF15087.1 KZN84236.1 - 8.6 4.5 7.5 13 4.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_72 PF03198.9 KZN84237.1 - 1e-100 336.7 0.1 2.1e-100 335.7 0.1 1.4 2 0 0 2 2 2 1 Glucanosyltransferase Methyltransf_32 PF13679.1 KZN84239.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sds3 PF08598.6 KZN84240.1 - 1.6e-45 155.1 8.4 1.1e-44 152.4 5.8 2.0 1 1 0 1 1 1 1 Sds3-like DUF416 PF04222.7 KZN84240.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Hemerythrin PF01814.18 KZN84241.1 - 2.4e-11 43.9 0.1 3.3e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HTH_29 PF13551.1 KZN84244.1 - 0.0018 18.4 2.4 0.0018 18.4 1.7 1.8 1 1 1 2 2 2 1 Winged helix-turn helix Myb_DNA-binding PF00249.26 KZN84244.1 - 0.0098 15.9 1.0 0.025 14.6 0.7 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rubrerythrin PF02915.12 KZN84244.1 - 0.11 12.8 0.8 0.19 12.0 0.6 1.3 1 0 0 1 1 1 0 Rubrerythrin PP_M1 PF03012.9 KZN84244.1 - 0.2 10.9 6.3 0.056 12.7 0.9 1.9 1 1 1 2 2 2 0 Phosphoprotein Ferritin PF00210.19 KZN84247.1 - 3.8e-11 42.9 0.0 4.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Thioredoxin_2 PF13098.1 KZN84248.1 - 0.0078 16.4 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Ras PF00071.17 KZN84249.1 - 1.3e-41 141.6 0.0 2.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Beta-lactamase PF00144.19 KZN84249.1 - 7.1e-40 137.0 0.0 1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Miro PF08477.8 KZN84249.1 - 5.5e-14 52.6 0.0 1.4e-12 48.1 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein DUF3471 PF11954.3 KZN84249.1 - 5.6e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) AAA_16 PF13191.1 KZN84249.1 - 0.12 12.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 KZN84249.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPMT PF05724.6 KZN84250.1 - 2.8e-31 108.6 0.0 3.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 KZN84250.1 - 5.6e-09 35.7 0.0 2.3e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN84250.1 - 4.1e-08 33.7 0.0 8.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84250.1 - 4.5e-08 32.9 0.0 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN84250.1 - 7.1e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84250.1 - 3.2e-05 24.3 0.0 5.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84250.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.7 KZN84250.1 - 0.0036 16.2 0.1 0.011 14.7 0.0 1.6 1 1 1 2 2 2 1 N2227-like protein TehB PF03848.9 KZN84250.1 - 0.0045 16.1 0.0 0.04 13.0 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB CheR PF01739.13 KZN84250.1 - 0.046 12.9 0.0 0.21 10.8 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 KZN84250.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ABC_membrane PF00664.18 KZN84251.1 - 3.2e-74 249.8 39.0 1.5e-40 139.3 11.3 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN84251.1 - 2.4e-67 225.4 0.0 1.6e-34 119.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 KZN84251.1 - 7.1e-12 45.6 1.1 1.3e-07 31.7 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 KZN84251.1 - 1.1e-11 45.2 0.1 0.005 16.8 0.0 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KZN84251.1 - 1.4e-11 44.0 10.3 0.00069 18.9 0.7 4.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KZN84251.1 - 1.2e-08 35.1 1.8 0.0057 16.7 0.0 4.5 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN84251.1 - 2.3e-08 33.4 1.5 0.00091 18.7 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KZN84251.1 - 4.4e-08 32.1 0.2 0.00011 20.8 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KZN84251.1 - 8.7e-08 31.5 0.0 0.009 15.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KZN84251.1 - 6.1e-07 30.2 0.0 0.003 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KZN84251.1 - 2.4e-05 23.8 0.1 1.1 8.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KZN84251.1 - 0.00011 22.0 0.0 0.83 9.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KZN84251.1 - 0.00018 21.6 1.0 6.8 6.9 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KZN84251.1 - 0.0004 20.0 1.0 2.6 7.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 KZN84251.1 - 0.0011 18.8 1.4 0.29 11.0 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KZN84251.1 - 0.0012 19.1 2.5 0.42 10.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN84251.1 - 0.0017 18.0 0.1 1.7 8.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) MobB PF03205.9 KZN84251.1 - 0.0058 16.3 0.0 2.6 7.7 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KZN84251.1 - 0.0067 16.1 0.0 1.7 8.4 0.0 3.1 2 1 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 KZN84251.1 - 0.01 16.1 3.4 0.47 10.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KZN84251.1 - 0.012 15.5 0.1 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KZN84251.1 - 0.015 14.7 0.2 3.8 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 KZN84251.1 - 0.016 13.9 0.1 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF3465 PF11948.3 KZN84251.1 - 0.018 14.8 0.1 0.58 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) PRK PF00485.13 KZN84251.1 - 0.019 14.5 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 KZN84251.1 - 0.036 14.2 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.20 KZN84251.1 - 0.036 13.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KZN84251.1 - 0.038 13.9 0.2 4.2 7.3 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 KZN84251.1 - 0.045 13.1 0.0 8.8 5.7 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MoaE PF02391.12 KZN84251.1 - 0.049 13.4 0.3 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 MoaE protein AAA_15 PF13175.1 KZN84251.1 - 0.059 12.4 0.0 0.74 8.7 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 KZN84251.1 - 0.068 12.9 0.8 0.93 9.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KZN84251.1 - 0.092 12.3 0.1 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.10 KZN84251.1 - 0.13 10.8 0.1 0.36 9.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AMP-binding PF00501.23 KZN84252.1 - 0 1048.7 0.0 1.4e-81 274.0 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KZN84252.1 - 1.6e-222 736.4 0.1 8.3e-49 166.0 0.0 7.2 7 0 0 7 7 7 6 Condensation domain PP-binding PF00550.20 KZN84252.1 - 1.5e-47 159.7 0.4 1.1e-10 41.6 0.0 5.8 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN84252.1 - 8.3e-18 65.1 0.8 0.002 19.0 0.0 5.4 4 1 0 4 4 4 4 AMP-binding enzyme C-terminal domain AAA_16 PF13191.1 KZN84253.1 - 2.5e-07 30.8 0.0 2.5e-07 30.8 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 KZN84253.1 - 3.9e-05 23.4 16.0 0.83 9.6 0.2 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat NACHT PF05729.7 KZN84253.1 - 0.00025 20.7 0.0 0.00074 19.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KZN84253.1 - 0.00083 19.4 3.4 0.0024 17.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain Vps39_1 PF10366.4 KZN84253.1 - 0.0049 16.8 0.3 0.27 11.2 0.1 3.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 ABC_tran PF00005.22 KZN84253.1 - 0.021 15.1 0.5 0.25 11.6 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Amidohydro_1 PF01979.15 KZN84254.1 - 3.9e-25 89.1 0.2 5.2e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN84254.1 - 4.6e-18 64.8 0.1 2e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 KZN84254.1 - 4.5e-08 33.4 4.7 5.4e-06 26.6 3.2 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN84254.1 - 1.8e-06 27.4 6.0 0.0021 17.3 0.1 3.1 3 0 0 3 3 3 2 Amidohydrolase family FA_desaturase PF00487.19 KZN84255.1 - 8.3e-18 64.7 16.3 1.5e-17 63.9 11.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KZN84255.1 - 2.1e-15 56.2 0.0 4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 KZN84256.1 - 7.7e-59 199.4 0.0 1.5e-58 198.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 PetG PF02529.10 KZN84256.1 - 0.52 9.8 2.9 1 8.9 2.0 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Mito_carr PF00153.22 KZN84257.1 - 7.3e-61 201.9 2.9 6.5e-20 70.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldose_epim PF01263.15 KZN84258.1 - 4.7e-50 170.3 0.4 6.2e-50 170.0 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Cupin_2 PF07883.6 KZN84258.1 - 0.019 14.4 0.1 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain GYF PF02213.11 KZN84258.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 GYF domain ACOX PF01756.14 KZN84259.1 - 3.5e-38 130.8 0.1 1.6e-37 128.7 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KZN84259.1 - 1.3e-25 90.1 2.0 2.5e-25 89.1 1.4 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KZN84259.1 - 4.4e-08 32.5 0.0 1.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KZN84259.1 - 0.0081 16.2 0.4 0.049 13.7 0.3 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.23 KZN84260.1 - 2.8e-53 180.8 0.1 3.4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN84260.1 - 2.9e-11 44.1 0.0 7.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 KZN84261.1 - 4.5e-25 88.1 0.0 5.3e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 KZN84262.1 - 4e-19 68.5 0.1 7.7e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84262.1 - 2.7e-05 23.9 11.4 6.6e-05 22.7 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.13 KZN84263.1 - 3.4e-23 81.5 0.0 1.6e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KZN84263.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain CTP_transf_1 PF01148.15 KZN84264.1 - 2.6e-18 66.6 5.3 7.7e-17 61.8 3.5 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family DEAD PF00270.24 KZN84265.1 - 1.2e-36 125.7 0.0 3.6e-36 124.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KZN84265.1 - 1.5e-21 75.6 0.0 3.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KZN84265.1 - 2.4e-19 68.9 0.0 8.3e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN84265.1 - 0.0072 16.1 3.8 0.0082 15.9 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Pilt PF15453.1 KZN84265.1 - 0.17 11.5 8.3 0.25 10.9 5.8 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CAF-1_p150 PF11600.3 KZN84265.1 - 1.6 8.0 28.9 2.4 7.4 20.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_S15 PF00312.17 KZN84267.1 - 9.1e-19 67.0 0.9 1.8e-18 66.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 RRS1 PF04939.7 KZN84267.1 - 0.024 14.1 1.4 0.057 12.8 0.1 2.1 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_S2 PF00318.15 KZN84268.1 - 1.9e-42 144.8 0.0 8.5e-23 80.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.17 KZN84269.1 - 8.8e-18 64.2 0.0 1.7e-17 63.2 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN84269.1 - 1.7e-07 31.7 0.0 2.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KZN84269.1 - 0.0013 18.8 0.1 0.049 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 KZN84269.1 - 0.0027 16.9 0.0 0.028 13.6 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family NACHT PF05729.7 KZN84269.1 - 0.0036 16.9 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN84269.1 - 0.0052 16.7 0.2 0.014 15.4 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KZN84269.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KZN84269.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KZN84269.1 - 0.031 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 KZN84269.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DAP3 PF10236.4 KZN84269.1 - 0.08 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 KZN84269.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KZN84269.1 - 0.14 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PseudoU_synth_1 PF01416.15 KZN84270.1 - 6.6e-28 97.2 0.0 2.2e-21 76.2 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 KZN84271.1 - 1.2e-27 95.2 0.1 2.5e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.18 KZN84272.1 - 0.00025 20.3 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 KZN84272.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF4661 PF15576.1 KZN84272.1 - 0.47 10.0 4.7 0.37 10.3 2.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Pribosyl_synth PF14572.1 KZN84273.1 - 1.7e-39 135.4 2.9 1.7e-34 119.2 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KZN84273.1 - 2.8e-32 110.8 0.0 1.6e-31 108.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KZN84273.1 - 1.6e-11 43.9 0.4 3.8e-11 42.7 0.2 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KZN84273.1 - 0.0043 16.2 0.3 0.007 15.5 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Fe_bilin_red PF05996.7 KZN84276.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase MFS_1 PF07690.11 KZN84277.1 - 3.3e-33 114.8 62.1 1.4e-24 86.4 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84277.1 - 1.5e-07 30.4 27.9 0.00035 19.2 10.7 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KZN84277.1 - 0.013 15.2 1.4 0.99 9.2 0.0 3.3 3 0 0 3 3 3 0 MFS_1 like family Pterin_4a PF01329.14 KZN84278.1 - 7.1e-07 28.9 0.1 2.6e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase UPRTase PF14681.1 KZN84278.1 - 0.054 12.6 0.3 2.3 7.3 0.2 2.2 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase HAD_2 PF13419.1 KZN84279.1 - 2.3e-17 63.7 0.0 3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN84279.1 - 2.4e-10 41.1 0.3 1.5e-05 25.5 0.1 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN84279.1 - 8.4e-09 35.8 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN84279.1 - 9.3e-09 34.8 0.1 2e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KZN84279.1 - 1.6e-05 24.7 0.0 0.0014 18.4 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase vATP-synt_AC39 PF01992.11 KZN84280.1 - 1.6e-107 359.5 0.0 1.8e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 KZN84281.1 - 5.7e-55 184.7 0.3 1.4e-54 183.5 0.2 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KZN84281.1 - 1.8e-27 94.8 0.1 3.8e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KZN84281.1 - 7.2e-23 80.5 2.4 7.2e-23 80.5 1.6 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF760 PF05542.6 KZN84281.1 - 0.017 15.2 0.0 0.2 11.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF760) RNA_pol_Rpb4 PF03874.11 KZN84282.1 - 1.2e-05 25.2 0.5 0.17 11.8 0.0 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb4 DUF899 PF05988.7 KZN84283.1 - 3.4e-69 232.5 0.0 4.1e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Redoxin PF08534.5 KZN84283.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin p450 PF00067.17 KZN84284.1 - 5.6e-51 173.4 0.0 7e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COG5 PF10392.4 KZN84286.1 - 0.022 14.7 0.2 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG7 PF10191.4 KZN84286.1 - 0.046 11.6 0.0 1.1 7.0 0.0 2.3 3 0 0 3 3 3 0 Golgi complex component 7 (COG7) SKG6 PF08693.5 KZN84288.1 - 6.5e-06 25.3 0.1 1.5e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KZN84288.1 - 0.21 11.1 5.1 0.4 10.2 3.3 1.6 1 1 0 1 1 1 0 Podoplanin Abhydrolase_6 PF12697.2 KZN84289.1 - 2.2e-30 106.2 0.2 6.8e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN84289.1 - 2.5e-16 59.9 0.0 2.8e-12 46.6 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN84289.1 - 2.4e-13 50.0 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KZN84289.1 - 3.1e-06 27.0 0.0 8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 KZN84289.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KZN84289.1 - 0.045 12.2 0.0 0.082 11.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family Muskelin_N PF06588.6 KZN84289.1 - 0.054 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Muskelin N-terminus Ser_hydrolase PF06821.8 KZN84289.1 - 0.1 12.1 0.1 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase PS_Dcarbxylase PF02666.10 KZN84290.1 - 6.4e-46 156.2 0.0 8e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Band_7 PF01145.20 KZN84292.1 - 7.2e-27 94.4 1.9 1.1e-26 93.8 1.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Cellulase PF00150.13 KZN84293.1 - 7.7e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.8 KZN84294.1 - 2.2e-14 53.5 0.0 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN84294.1 - 1.9e-09 37.0 0.0 9e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 KZN84294.1 - 4.1e-08 32.4 0.4 9.1e-08 31.2 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KZN84294.1 - 8.5e-08 32.3 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84294.1 - 5.6e-07 29.4 0.0 9.8e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KZN84294.1 - 7.5e-05 21.7 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 KZN84294.1 - 0.0002 19.9 0.0 0.018 13.5 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KZN84294.1 - 0.00095 18.6 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 KZN84294.1 - 0.0042 16.5 0.0 0.033 13.6 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 KZN84294.1 - 0.0086 15.5 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Cupin_2 PF07883.6 KZN84295.1 - 1.5e-10 40.4 0.1 1.8e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KZN84295.1 - 0.015 14.6 0.0 0.66 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KZN84295.1 - 0.059 12.7 0.0 0.75 9.2 0.0 2.2 1 1 0 1 1 1 0 Cupin AraC_binding PF02311.14 KZN84295.1 - 0.085 12.5 0.1 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain FAD_binding_3 PF01494.14 KZN84296.1 - 2.6e-25 89.2 0.0 4.4e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN84296.1 - 2.1e-12 46.6 1.4 7.6e-05 21.7 1.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN84296.1 - 2.9e-07 30.7 0.5 8.7e-05 22.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN84296.1 - 6e-06 26.2 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN84296.1 - 6.2e-06 25.3 3.3 1e-05 24.6 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KZN84296.1 - 7.1e-06 24.9 0.7 3.3e-05 22.7 0.1 1.9 1 1 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KZN84296.1 - 1.2e-05 25.2 0.9 3.4e-05 23.7 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN84296.1 - 3.9e-05 22.3 0.9 0.00012 20.7 0.9 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KZN84296.1 - 0.00019 20.5 0.3 0.00032 19.8 0.2 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KZN84296.1 - 0.00033 19.6 1.2 0.00054 18.9 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KZN84296.1 - 0.003 17.1 0.3 0.0051 16.3 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KZN84296.1 - 0.0031 17.6 0.0 0.0051 16.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KZN84296.1 - 0.0054 16.4 0.5 0.0085 15.7 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KZN84296.1 - 0.006 15.7 2.5 0.009 15.1 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 KZN84296.1 - 0.0078 15.0 0.0 0.032 13.0 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 KZN84296.1 - 0.019 13.9 1.0 0.15 10.9 1.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KZN84296.1 - 0.026 13.5 0.2 7.5 5.5 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 KZN84296.1 - 0.033 13.5 0.3 0.054 12.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 KZN84297.1 - 2.4e-09 36.9 9.1 4.7e-09 36.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN84297.1 - 0.034 13.0 0.2 0.061 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Bac_luciferase PF00296.15 KZN84298.1 - 1e-62 212.0 1.0 1.5e-62 211.5 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.1 KZN84299.1 - 2.3e-18 67.0 0.0 3.9e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN84299.1 - 1.6e-15 56.3 0.3 1.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN84299.1 - 2.5e-06 27.4 0.0 7.5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN84299.1 - 5.4e-05 22.2 0.1 0.00016 20.7 0.1 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN84299.1 - 0.00094 19.1 0.0 0.0035 17.2 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN84299.1 - 0.11 12.2 0.6 0.83 9.4 0.0 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding DnaB_2 PF07261.6 KZN84299.1 - 0.12 12.0 0.4 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment GIDA PF01134.17 KZN84299.1 - 0.19 10.5 0.1 10 4.8 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KZN84299.1 - 0.2 10.8 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 KZN84300.1 - 4.6e-18 65.6 0.0 7.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84300.1 - 3.8e-10 39.9 0.0 5.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN84300.1 - 9.3e-09 35.1 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN84300.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KZN84300.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TIR-like PF10137.4 KZN84300.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Catalase PF00199.14 KZN84301.1 - 1.1e-139 465.4 0.2 1.4e-139 465.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN84301.1 - 1.9e-10 40.4 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_7 PF13508.1 KZN84302.1 - 3.2e-08 33.6 0.0 5.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN84302.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN84302.1 - 2.1e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN84302.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KZN84302.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN84302.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.20 KZN84303.1 - 8.9e-09 35.4 0.1 2.3e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84303.1 - 0.00021 20.9 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 KR domain F-box PF00646.28 KZN84304.1 - 2.3e-05 23.9 0.4 0.0024 17.4 0.0 2.8 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 KZN84304.1 - 3.2e-05 23.5 0.1 0.00011 21.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like Sulfate_transp PF00916.15 KZN84305.1 - 9.6e-48 162.5 5.9 1.9e-47 161.6 4.1 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KZN84305.1 - 1.2e-26 92.1 4.5 1.2e-26 92.1 3.1 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KZN84305.1 - 2.3e-15 56.0 0.0 3.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KZN84305.1 - 2.2e-05 24.3 0.0 0.00011 22.1 0.0 2.2 2 1 0 2 2 2 1 STAS domain EIF_2_alpha PF07541.7 KZN84306.1 - 3.5e-38 129.8 0.0 9e-38 128.5 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KZN84306.1 - 1.8e-07 31.1 0.2 3.9e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.7 KZN84307.1 - 6e-07 28.2 22.6 5.9e-06 24.9 14.0 2.6 1 1 1 2 2 2 1 Polycystin cation channel Hydrolase PF00702.21 KZN84308.1 - 2.2e-22 80.5 0.0 2.7e-21 76.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN84308.1 - 1.1e-21 77.8 0.0 2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KZN84308.1 - 4.1e-21 75.0 0.0 1.3e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KZN84308.1 - 0.00027 20.8 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN84308.1 - 0.001 18.7 0.1 0.0059 16.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KZN84308.1 - 0.071 12.4 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Mt_ATP-synt_B PF05405.9 KZN84308.1 - 0.78 9.1 4.1 14 5.0 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease_2 PF13520.1 KZN84309.1 - 3.4e-45 154.3 52.4 7.1e-45 153.3 36.3 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84309.1 - 2.7e-17 62.2 45.8 8.7e-17 60.6 31.8 1.7 1 1 0 1 1 1 1 Amino acid permease CinA PF02464.12 KZN84310.1 - 4.4e-45 152.8 0.2 5.1e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein DUF1455 PF07306.6 KZN84310.1 - 0.016 15.3 0.3 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Aldo_ket_red PF00248.16 KZN84311.1 - 1.4e-14 53.5 0.0 2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 KZN84312.1 - 9.2e-10 37.9 0.0 3e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN84312.1 - 4.7e-08 33.0 0.1 0.0023 17.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KZN84312.1 - 2.3e-07 30.2 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KZN84312.1 - 0.0043 16.4 0.0 0.5 9.6 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 KZN84312.1 - 0.009 15.0 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_antitermQ PF06530.7 KZN84312.1 - 0.034 13.7 0.1 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q AP_endonuc_2 PF01261.19 KZN84312.1 - 0.05 12.8 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 KZN84313.1 - 2.8e-09 36.7 7.8 7.2e-09 35.4 5.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb1_5 PF04998.12 KZN84314.1 - 5.8e-86 288.1 0.2 9.8e-86 287.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KZN84314.1 - 1.2e-85 287.7 0.0 1.9e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KZN84314.1 - 1.5e-67 226.7 0.0 3.7e-67 225.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KZN84314.1 - 1.1e-34 119.4 0.0 2.7e-33 114.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KZN84314.1 - 9.2e-28 96.1 0.1 2.5e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 KZN84314.1 - 0.15 11.9 1.6 0.61 9.9 1.1 2.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.22 KZN84315.1 - 1e-47 162.0 0.0 1.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KZN84315.1 - 3.7e-39 132.9 4.2 6.3e-39 132.2 2.9 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KZN84315.1 - 1.3e-17 63.4 0.0 2.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KZN84315.1 - 3.5e-05 23.7 0.0 8.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KZN84315.1 - 0.00024 20.5 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 KZN84315.1 - 0.00058 19.6 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 KZN84315.1 - 0.0035 16.5 0.0 0.0072 15.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.20 KZN84315.1 - 0.0077 16.3 0.1 0.019 15.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HORMA PF02301.13 KZN84316.1 - 3e-49 167.3 0.3 3.4e-49 167.1 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF218 PF02698.12 KZN84317.1 - 4.9e-07 29.3 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain Serglycin PF04360.7 KZN84318.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Serglycin FA_desaturase PF00487.19 KZN84319.1 - 0.0045 16.4 1.7 0.068 12.5 0.0 2.3 2 0 0 2 2 2 2 Fatty acid desaturase zf-CCCH PF00642.19 KZN84321.1 - 0.00013 21.5 1.1 0.00022 20.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KZN84321.1 - 0.012 15.5 3.2 0.023 14.6 2.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type 14-3-3 PF00244.15 KZN84321.1 - 0.075 12.1 0.4 0.13 11.2 0.3 1.3 1 0 0 1 1 1 0 14-3-3 protein Sec1 PF00995.18 KZN84322.1 - 1.2e-154 516.0 0.0 1.5e-154 515.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FYVE PF01363.16 KZN84324.1 - 2.2e-23 81.9 25.4 4.6e-17 61.6 3.7 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KZN84324.1 - 0.0014 18.7 8.8 0.056 13.5 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KZN84324.1 - 0.013 15.3 6.9 0.013 15.3 4.8 3.5 3 1 1 4 4 4 0 AN1-like Zinc finger IBR PF01485.16 KZN84324.1 - 0.017 15.0 3.6 0.017 15.0 2.5 3.1 3 0 0 3 3 3 0 IBR domain TMF_TATA_bd PF12325.3 KZN84324.1 - 0.079 12.6 3.1 0.09 12.5 0.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GLTP PF08718.6 KZN84326.1 - 3.4e-45 153.7 0.0 4.4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cir_N PF10197.4 KZN84326.1 - 0.039 13.9 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR PH_4 PF15404.1 KZN84327.1 - 1.9e-60 203.5 0.0 7.6e-60 201.6 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 KZN84327.1 - 5.6e-21 73.7 0.3 1.2e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 KZN84327.1 - 6.6e-09 35.9 0.0 0.00013 22.1 0.0 3.9 3 1 0 3 3 3 2 PH domain Peptidase_S24 PF00717.18 KZN84328.1 - 1.8e-07 30.6 0.1 1.4e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KZN84328.1 - 0.01 15.3 0.0 2.3 7.7 0.0 2.4 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Macro PF01661.16 KZN84329.1 - 2e-40 137.3 0.1 2.8e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain DUF3929 PF13066.1 KZN84329.1 - 0.047 13.4 1.4 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) GATA PF00320.22 KZN84330.1 - 8.4e-15 53.8 5.2 1.6e-14 52.9 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 KZN84330.1 - 0.23 11.5 1.9 0.49 10.4 1.3 1.5 1 0 0 1 1 1 0 zinc-finger COesterase PF00135.23 KZN84331.1 - 2.3e-113 379.7 0.3 2.9e-113 379.4 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN84331.1 - 2.2e-05 24.1 0.5 0.00034 20.2 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN84331.1 - 0.01 15.0 0.2 0.02 14.1 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family CaMKII_AD PF08332.5 KZN84332.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 KZN84332.1 - 0.059 13.5 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) GCS PF03074.11 KZN84333.1 - 3.6e-155 516.5 0.0 9e-155 515.2 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase NDUF_B7 PF05676.8 KZN84334.1 - 2.4e-32 110.1 5.6 2.9e-32 109.8 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KZN84334.1 - 0.0056 16.4 3.5 0.008 15.9 2.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_2 PF12796.2 KZN84335.1 - 9.9e-13 48.2 0.8 3.9e-07 30.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84335.1 - 9.9e-11 40.8 2.7 1.1e-08 34.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KZN84335.1 - 1.2e-10 41.2 1.7 8.8e-07 28.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN84335.1 - 2.7e-10 40.4 0.6 4.6e-05 23.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN84335.1 - 2.8e-08 33.2 1.9 0.0024 17.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KZN84335.1 - 2.1e-05 24.0 0.1 0.00019 21.0 0.0 2.5 2 0 0 2 2 2 1 KilA-N domain Med3 PF11593.3 KZN84335.1 - 0.062 12.5 8.4 0.041 13.1 3.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal HALZ PF02183.13 KZN84335.1 - 1.7 8.3 5.6 18 5.1 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1212 PF06738.7 KZN84337.1 - 1.2e-56 191.2 9.8 3.5e-50 170.1 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KZN84337.1 - 3.9e-32 110.9 8.5 3.9e-32 110.9 5.9 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) MIS13 PF08202.6 KZN84338.1 - 4.8e-44 150.6 1.1 9.9e-44 149.6 0.8 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AT_hook PF02178.14 KZN84338.1 - 0.014 14.9 13.9 0.67 9.8 1.9 3.4 2 0 0 2 2 2 0 AT hook motif PS_Dcarbxylase PF02666.10 KZN84339.1 - 6.4e-50 169.2 0.0 1e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KZN84339.1 - 2.3e-33 113.9 0.0 2.2e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KZN84339.1 - 0.0036 17.4 0.6 0.011 15.8 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KZN84339.1 - 0.015 14.5 0.1 0.063 12.6 0.1 2.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KZN84339.1 - 0.057 13.3 0.0 0.3 11.1 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain Sugar_tr PF00083.19 KZN84340.1 - 2.4e-87 293.3 15.5 3e-87 293.0 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84340.1 - 7.7e-36 123.5 60.6 5.9e-32 110.7 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KZN84341.1 - 8.4e-63 211.9 0.0 1.1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84341.1 - 3.4e-30 104.9 0.0 5.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84341.1 - 0.048 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN84341.1 - 0.13 12.0 0.0 0.98 9.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-UBR PF02207.15 KZN84342.1 - 7.4e-16 57.6 8.1 7.4e-16 57.6 5.6 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AUX_IAA PF02309.11 KZN84342.1 - 0.22 11.2 3.2 0.44 10.2 2.2 1.4 1 0 0 1 1 1 0 AUX/IAA family MCM PF00493.18 KZN84343.1 - 1.2e-136 454.9 0.0 1.7e-136 454.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KZN84343.1 - 1.8e-35 122.2 39.8 1.8e-35 122.2 27.6 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KZN84343.1 - 1.5e-16 60.9 0.0 4.3e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN84343.1 - 7.2e-08 31.8 0.1 7.2e-06 25.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN84343.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KZN84343.1 - 0.0028 17.1 0.1 0.021 14.3 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KZN84343.1 - 0.017 14.7 0.1 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zn_ribbon_2 PF12674.2 KZN84343.1 - 0.031 14.6 0.3 0.11 12.8 0.2 2.0 1 0 0 1 1 1 0 Putative zinc ribbon domain Pal1 PF08316.6 KZN84344.1 - 2.6e-47 160.8 2.7 8.1e-46 155.9 1.9 2.8 1 1 0 1 1 1 1 Pal1 cell morphology protein DUF2250 PF10007.4 KZN84346.1 - 0.011 15.6 1.4 0.026 14.4 1.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Med31 PF05669.7 KZN84347.1 - 1.4e-29 101.7 0.0 1.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 SOH1 Palm_thioest PF02089.10 KZN84349.1 - 2.8e-59 200.3 0.0 3.6e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KZN84349.1 - 0.032 13.3 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) HTH_18 PF12833.2 KZN84349.1 - 0.055 13.5 0.0 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain GluR_Homer-bdg PF10606.4 KZN84350.1 - 0.11 12.4 0.4 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor zf-C2H2_4 PF13894.1 KZN84351.1 - 0.019 15.2 5.9 0.38 11.2 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN84351.1 - 0.12 12.7 1.3 6.8 7.2 0.0 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 KZN84352.1 - 8.5e-65 218.6 0.0 1.5e-64 217.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KZN84352.1 - 4.5e-05 23.3 0.4 9.8e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KZN84352.1 - 0.045 13.3 6.4 0.76 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Methyltransf_16 PF10294.4 KZN84353.1 - 1.3e-15 57.3 0.0 2.2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KZN84353.1 - 0.00032 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sugar_tr PF00083.19 KZN84355.1 - 4.9e-82 275.9 22.4 6.3e-82 275.5 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84355.1 - 1e-14 54.0 46.8 1.5e-13 50.1 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C14 PF00656.17 KZN84357.1 - 2.9e-67 226.9 0.0 3.6e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 KZN84357.1 - 0.18 11.0 0.6 5.8 6.1 0.1 2.3 1 1 1 2 2 2 0 Peptidase C13 family F-box-like PF12937.2 KZN84358.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN84358.1 - 0.15 11.7 0.3 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 F-box domain DUF3712 PF12505.3 KZN84359.1 - 4.7e-29 100.9 0.3 1.1e-28 99.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2236 PF09995.4 KZN84360.1 - 9.9e-47 159.2 3.1 1.2e-46 159.0 2.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.6 KZN84360.1 - 0.013 16.0 0.0 0.054 14.0 0.0 2.1 1 1 0 1 1 1 0 MDMPI C-terminal domain IDO PF01231.13 KZN84362.1 - 6.5e-168 558.5 0.0 8.1e-168 558.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CsbD PF05532.7 KZN84362.1 - 1.5e-14 53.3 23.6 9.8e-10 37.9 4.0 3.1 3 0 0 3 3 3 2 CsbD-like COesterase PF00135.23 KZN84363.1 - 1.7e-17 63.3 0.8 3.1e-12 45.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Esterase_phd PF10503.4 KZN84363.1 - 0.00049 19.4 0.1 0.00054 19.2 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KZN84363.1 - 0.018 14.5 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KZN84363.1 - 0.02 14.7 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84363.1 - 0.047 13.4 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KZN84363.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PolyA_pol_RNAbd PF12627.2 KZN84363.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Aminotran_5 PF00266.14 KZN84364.1 - 3.8e-93 312.1 0.0 4.5e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KZN84364.1 - 1.5e-05 24.3 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KZN84364.1 - 0.014 14.4 0.0 0.038 13.0 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family BAR PF03114.13 KZN84365.1 - 1.6e-60 204.5 9.1 2e-60 204.1 6.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KZN84365.1 - 1.2e-13 50.2 0.1 2.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN84365.1 - 1.2e-12 47.1 0.1 2.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KZN84365.1 - 9.7e-09 34.5 0.2 2.1e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 KZN84365.1 - 0.014 14.6 6.7 1.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Vps5 C terminal like UBA PF00627.26 KZN84365.1 - 0.017 14.9 0.2 0.76 9.6 0.1 2.7 2 0 0 2 2 2 0 UBA/TS-N domain AHS1 PF02682.11 KZN84365.1 - 0.041 13.3 0.5 0.077 12.4 0.4 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 YlqD PF11068.3 KZN84365.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.0 3 1 0 3 3 3 0 YlqD protein TMPIT PF07851.8 KZN84365.1 - 1.5 7.8 7.7 0.27 10.2 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF4140 PF13600.1 KZN84365.1 - 2.6 8.5 6.1 10 6.5 2.1 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) STE2 PF02116.10 KZN84366.1 - 4.4e-100 334.3 20.0 5.3e-100 334.1 13.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Orbi_NS3 PF01616.11 KZN84366.1 - 0.034 13.1 1.5 0.35 9.8 0.3 2.3 1 1 1 2 2 2 0 Orbivirus NS3 SP_C-Propep PF08999.5 KZN84366.1 - 0.34 10.4 3.9 0.75 9.3 1.9 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide CcmD PF04995.9 KZN84366.1 - 0.54 10.0 15.0 0.64 9.7 0.1 3.7 3 1 0 3 3 3 0 Heme exporter protein D (CcmD) Oxidored_q2 PF00420.19 KZN84366.1 - 2.6 7.7 13.3 1.7 8.3 2.4 3.1 2 2 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2929 PF11151.3 KZN84366.1 - 3 7.9 9.6 0.15 12.1 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) UEV PF05743.8 KZN84367.1 - 8.4e-39 131.9 0.1 8.4e-39 131.9 0.0 1.5 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 KZN84367.1 - 6.3e-21 73.7 0.1 1.6e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 KZN84367.1 - 0.078 12.3 0.1 0.078 12.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Alpha_GJ PF03229.8 KZN84367.1 - 2.5 8.4 12.5 0.72 10.1 5.4 2.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J Opy2 PF09463.5 KZN84368.1 - 5.6e-09 35.9 23.6 1.1e-08 34.9 16.3 1.5 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KZN84368.1 - 0.00023 20.7 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KZN84368.1 - 0.00025 20.2 1.4 0.00058 19.1 1.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Chitin_synth_1 PF01644.12 KZN84369.1 - 2.7e-67 225.6 0.0 4.1e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KZN84369.1 - 8.9e-28 95.8 0.1 1.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KZN84369.1 - 1.1e-25 90.0 0.0 5.3e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KZN84369.1 - 7.7e-13 48.5 0.1 7.7e-13 48.5 0.0 2.7 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN84369.1 - 2.1e-09 37.5 0.0 6.3e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UQ_con PF00179.21 KZN84370.1 - 2.2e-37 127.6 0.0 3.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KZN84370.1 - 0.084 12.5 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 UEV domain Prok-E2_B PF14461.1 KZN84370.1 - 0.093 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B TAF8_C PF10406.4 KZN84372.1 - 3.3e-20 71.8 0.0 8.7e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KZN84372.1 - 4.3e-09 35.9 0.0 7.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated PAP2 PF01569.16 KZN84372.1 - 0.038 13.6 0.2 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 PAP2 superfamily Mitochondr_Som1 PF11093.3 KZN84373.1 - 2.6e-12 46.3 0.1 3.6e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.6 KZN84374.1 - 0.00026 19.9 0.0 0.0031 16.4 0.0 2.3 2 1 0 2 2 2 1 Rad51 DUF913 PF06025.7 KZN84374.1 - 0.18 10.5 0.2 0.31 9.7 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PALP PF00291.20 KZN84375.1 - 9.5e-77 258.2 0.2 1.4e-76 257.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KZN84375.1 - 0.011 14.7 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.7 KZN84376.1 - 4.3e-45 153.0 0.0 6.1e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KZN84376.1 - 7e-45 152.5 0.0 1.2e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KZN84376.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Isochorismatase PF00857.15 KZN84377.1 - 6.6e-25 88.0 0.0 1.6e-24 86.8 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 KZN84377.1 - 2.1e-23 83.1 0.0 3.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 KZN84377.1 - 2e-07 31.4 0.0 8.8e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN84377.1 - 1.9e-05 24.4 0.0 6.8e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN84377.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN84377.1 - 0.1 12.8 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.8 KZN84377.1 - 0.2 11.2 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lipase_GDSL PF00657.17 KZN84378.1 - 1.5e-15 57.7 0.1 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KZN84378.1 - 1.2e-13 51.5 0.8 1.5e-13 51.2 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ECH PF00378.15 KZN84379.1 - 1.2e-39 135.9 0.1 2.3e-39 134.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HSP20 PF00011.16 KZN84380.1 - 9.2e-18 63.9 0.1 4.1e-17 61.9 0.1 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Tbf5 PF06331.7 KZN84381.1 - 7.1e-24 83.3 1.7 8.3e-24 83.1 1.2 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 KZN84381.1 - 0.079 12.5 0.5 0.087 12.4 0.3 1.2 1 0 0 1 1 1 0 SGF29 tudor-like domain DIOX_N PF14226.1 KZN84382.1 - 2.3e-24 86.1 0.0 2.1e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN84382.1 - 2e-13 50.4 0.0 3.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 KZN84385.1 - 7.4e-28 96.3 12.1 1.7e-10 40.7 0.0 5.4 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KZN84385.1 - 5.6e-14 51.5 15.9 0.0048 16.8 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KZN84385.1 - 2.2e-06 27.7 0.1 6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN84385.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_16 PF13432.1 KZN84385.1 - 1.8e-05 25.2 3.3 0.7 10.6 0.3 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN84385.1 - 2.1e-05 24.7 5.4 3.2 8.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84385.1 - 0.00034 20.1 0.9 1.7 8.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF676 PF05057.9 KZN84385.1 - 0.00044 19.5 0.1 0.0014 17.9 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.1 KZN84385.1 - 0.00099 18.7 5.4 2.1 8.3 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN84385.1 - 0.0016 18.5 3.9 1.3 9.1 0.4 3.1 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KZN84385.1 - 0.0017 17.9 6.2 0.53 9.9 0.3 4.0 3 1 0 3 3 3 1 TPR repeat Abhydrolase_5 PF12695.2 KZN84385.1 - 0.0074 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_14 PF13428.1 KZN84385.1 - 0.011 16.2 10.3 1 10.1 0.2 5.9 5 2 2 7 7 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN84385.1 - 0.013 15.3 7.7 0.094 12.6 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84385.1 - 0.028 14.0 7.4 0.4 10.3 0.2 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN84385.1 - 0.039 14.4 5.5 4.7 7.8 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Lipase_3 PF01764.20 KZN84385.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KZN84385.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Cutinase SLAC1 PF03595.12 KZN84386.1 - 3.1e-87 292.2 44.8 3.5e-87 292.1 31.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_43 PF04616.9 KZN84387.1 - 9.7e-35 120.0 3.8 1.2e-34 119.7 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KZN84388.1 - 1.6e-14 53.4 0.3 3.1e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84388.1 - 2.6e-05 24.0 8.9 4.6e-05 23.2 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 KZN84389.1 - 1.3e-163 544.6 0.2 1.5e-163 544.3 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KZN84389.1 - 4.8e-07 29.7 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KZN84389.1 - 0.00027 20.9 0.1 0.00061 19.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 KZN84390.1 - 3.2e-62 210.4 49.3 3.9e-62 210.1 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84390.1 - 6.9e-27 93.9 42.0 9.3e-27 93.4 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KZN84392.1 - 4.4e-103 345.2 28.3 5.2e-103 345.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84392.1 - 5.9e-20 71.2 36.7 1.5e-15 56.7 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrophobin PF01185.13 KZN84393.1 - 9.4e-05 22.7 7.7 0.00015 22.1 5.3 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN84393.1 - 0.032 14.3 2.4 0.032 14.3 1.7 2.3 2 0 0 2 2 2 0 Granulin GMC_oxred_N PF00732.14 KZN84394.1 - 5.8e-62 209.5 0.2 7.6e-62 209.1 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN84394.1 - 3.1e-36 124.8 0.0 5.1e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN84394.1 - 3.1e-06 26.3 0.2 7.1e-05 21.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN84394.1 - 7.7e-06 25.8 0.1 2.2e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN84394.1 - 7.5e-05 21.7 0.2 0.0037 16.1 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN84394.1 - 0.00013 21.9 0.0 0.0031 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN84394.1 - 0.00076 18.4 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN84394.1 - 0.0037 15.8 0.1 0.006 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KZN84394.1 - 0.0055 17.0 0.1 0.022 15.1 0.1 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN84394.1 - 0.0069 15.5 0.5 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KZN84394.1 - 0.077 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Rieske PF00355.21 KZN84395.1 - 1.1e-10 40.9 0.0 1.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KZN84395.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RNase_T PF00929.19 KZN84396.1 - 4.3e-22 79.1 0.0 6.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.19 KZN84397.1 - 2.9e-18 65.5 0.0 1.8e-17 63.0 0.0 2.2 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KZN84397.1 - 8.9e-13 47.8 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KZN84397.1 - 0.00085 19.4 0.0 0.0069 16.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like TauD PF02668.11 KZN84398.1 - 4.1e-60 203.6 1.2 7.3e-60 202.7 0.4 1.7 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KZN84398.1 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KZN84398.1 - 0.0058 15.5 0.1 0.016 14.1 0.0 1.7 1 1 0 1 1 1 1 CsiD Mito_carr PF00153.22 KZN84399.1 - 4.6e-66 218.5 2.6 5.9e-22 77.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KZN84399.1 - 0.083 12.8 0.0 17 5.4 0.0 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Tubulin PF00091.20 KZN84400.1 - 1.4e-65 221.1 0.0 1.9e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KZN84400.1 - 5.9e-44 149.1 0.0 8.9e-44 148.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KZN84400.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain MS_channel PF00924.13 KZN84401.1 - 1.7e-25 89.5 2.3 3.7e-25 88.4 1.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KZN84401.1 - 0.00032 19.7 0.3 0.0008 18.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KZN84401.1 - 0.0014 17.8 0.0 0.003 16.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KZN84401.1 - 0.0015 18.5 0.1 0.004 17.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN84401.1 - 0.0031 17.2 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain DUF2648 PF10855.3 KZN84401.1 - 0.036 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Pkinase PF00069.20 KZN84402.1 - 5.5e-59 199.4 0.0 4.7e-39 134.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84402.1 - 4.1e-26 91.5 0.0 2.7e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KZN84402.1 - 7.6e-12 45.2 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.18 KZN84402.1 - 2.2e-07 30.8 0.0 0.0057 16.4 0.1 2.8 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN84402.1 - 2.6e-07 29.8 2.3 3.5e-05 22.9 0.0 3.0 4 0 0 4 4 4 2 Kinase-like Kdo PF06293.9 KZN84402.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4546 PF15079.1 KZN84402.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Seadorna_VP7 PF07387.6 KZN84402.1 - 0.089 11.6 0.1 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Fungal_trans PF04082.13 KZN84403.1 - 1.5e-26 92.8 0.1 2.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84403.1 - 1.7e-09 37.4 10.9 1.7e-09 37.4 7.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNase PF00565.12 KZN84404.1 - 0.12 12.6 0.0 2.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal nuclease homologue adh_short PF00106.20 KZN84406.1 - 1.8e-23 83.2 0.0 2.5e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84406.1 - 1.8e-13 50.8 0.0 2.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN84406.1 - 1.6e-05 24.6 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN84406.1 - 0.0002 20.8 0.0 0.002 17.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN84406.1 - 0.00071 19.6 0.1 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding ABC2_membrane PF01061.19 KZN84407.1 - 2e-66 223.1 49.1 1.8e-35 122.0 14.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN84407.1 - 2.3e-40 138.0 0.0 8.5e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN84407.1 - 1.4e-22 79.2 11.4 2.3e-19 68.9 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter AAA_21 PF13304.1 KZN84407.1 - 5.9e-08 33.0 0.0 0.29 11.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KZN84407.1 - 3e-07 30.0 0.0 0.018 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KZN84407.1 - 2.3e-06 26.8 33.2 2.5e-06 26.8 9.1 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.1 KZN84407.1 - 1.3e-05 25.3 0.1 0.13 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN84407.1 - 3.4e-05 24.6 0.0 0.036 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN84407.1 - 0.0002 20.5 0.0 0.0013 17.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN84407.1 - 0.00048 20.1 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KZN84407.1 - 0.00058 19.1 0.0 0.59 9.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KZN84407.1 - 0.00069 19.9 0.1 0.085 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN84407.1 - 0.0011 18.7 0.7 0.83 9.2 0.1 2.6 2 0 0 2 2 2 2 NACHT domain UPF0079 PF02367.12 KZN84407.1 - 0.0013 18.3 1.4 0.36 10.4 0.3 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 P5-ATPase PF12409.3 KZN84407.1 - 0.0015 18.3 0.4 0.005 16.6 0.3 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter AAA_19 PF13245.1 KZN84407.1 - 0.0017 18.1 0.1 0.66 9.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 KZN84407.1 - 0.0024 16.8 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 KZN84407.1 - 0.0036 17.1 0.1 0.92 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN84407.1 - 0.0048 16.3 0.2 0.24 10.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KZN84407.1 - 0.0051 16.2 3.1 0.18 11.2 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KZN84407.1 - 0.0077 15.8 0.0 0.55 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 KZN84407.1 - 0.01 15.3 2.0 2.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KZN84407.1 - 0.011 15.6 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 KZN84407.1 - 0.014 14.3 0.3 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.13 KZN84407.1 - 0.038 13.4 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 KZN84407.1 - 0.041 13.7 0.0 0.49 10.3 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KZN84407.1 - 0.048 14.1 0.0 5.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KZN84407.1 - 0.073 12.4 1.7 5.5 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 KZN84407.1 - 0.1 12.8 0.4 8.4 6.6 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 KZN84407.1 - 0.22 10.7 0.5 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 KZN84407.1 - 0.23 10.9 1.1 16 4.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KZN84407.1 - 0.36 10.4 0.0 1.7 8.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 KZN84407.1 - 1.9 7.9 4.4 3.1 7.1 0.8 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Oxidored_FMN PF00724.15 KZN84408.1 - 1.1e-77 261.3 0.0 1.4e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.19 KZN84409.1 - 2.3e-105 352.7 24.2 2.7e-105 352.5 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84409.1 - 1.6e-23 83.0 26.8 7.5e-21 74.2 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.1 KZN84409.1 - 0.068 13.1 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family Phe_tRNA-synt_N PF02912.13 KZN84409.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Hexapep_2 PF14602.1 KZN84410.1 - 4.1e-16 58.2 9.6 2.2e-11 43.0 0.6 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KZN84410.1 - 1.3e-15 57.1 0.0 2.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KZN84410.1 - 1.1e-13 49.9 12.4 1.4e-11 43.3 1.0 4.0 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) MFS_1 PF07690.11 KZN84411.1 - 7e-39 133.5 28.6 7e-39 133.5 19.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN84412.1 - 6.5e-31 107.3 38.2 1.9e-27 95.8 27.2 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN84413.1 - 5.7e-06 25.2 1.6 6.6e-06 25.0 1.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KZN84414.1 - 4.4e-23 81.5 22.2 4.4e-23 81.5 15.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pro_racemase PF05544.6 KZN84415.1 - 1.4e-61 208.1 0.0 1.9e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Peptidase_M24 PF00557.19 KZN84416.1 - 2e-38 132.0 0.0 2.7e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KZN84416.1 - 0.00045 20.0 5.3 0.001 18.8 3.7 1.6 1 0 0 1 1 1 1 MYND finger 3Beta_HSD PF01073.14 KZN84417.1 - 7.7e-46 156.0 0.0 4.3e-41 140.4 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN84417.1 - 1.6e-21 76.7 0.2 9.4e-21 74.3 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN84417.1 - 2.5e-13 49.5 0.0 1.4e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KZN84417.1 - 2.5e-06 26.6 0.1 1.6e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN84417.1 - 0.0015 18.5 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN84417.1 - 0.088 11.6 0.0 0.39 9.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein UQ_con PF00179.21 KZN84419.1 - 9.2e-06 25.1 0.1 4.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Kdo PF06293.9 KZN84420.1 - 3e-06 26.4 0.0 1.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN84420.1 - 0.00023 20.9 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN84420.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain MCRS_N PF13325.1 KZN84420.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein RhoGAP PF00620.22 KZN84421.1 - 6.1e-35 120.0 0.3 1.1e-34 119.2 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KZN84421.1 - 2.3e-25 88.4 42.8 1.4e-11 44.2 4.5 4.8 5 0 0 5 5 5 4 LIM domain DUF1272 PF06906.6 KZN84421.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF1272) T2SE PF00437.15 KZN84421.1 - 0.024 13.5 0.1 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF164 PF02591.10 KZN84421.1 - 9.7 6.1 10.9 4 7.3 0.1 3.6 3 0 0 3 3 3 0 Putative zinc ribbon domain MFS_1 PF07690.11 KZN84422.1 - 4.1e-27 94.8 46.7 1.1e-26 93.3 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN84422.1 - 3.5e-05 22.2 3.3 3.5e-05 22.2 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_4 PF07993.7 KZN84423.1 - 1.2e-35 122.6 0.3 3.5e-34 117.8 0.2 2.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KZN84423.1 - 2.8e-07 30.1 0.0 5.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN84423.1 - 0.15 10.7 0.5 0.85 8.2 0.4 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 KZN84424.1 - 7.1e-05 22.3 0.0 9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AA_permease_2 PF13520.1 KZN84425.1 - 2.4e-45 154.8 43.8 3.3e-24 85.2 8.7 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KZN84425.1 - 4.9e-14 51.5 37.1 7.9e-08 31.0 9.2 2.4 1 1 1 2 2 2 2 Amino acid permease Fungal_trans_2 PF11951.3 KZN84426.1 - 5.8e-38 130.4 2.6 7.2e-38 130.1 1.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Menin PF05053.8 KZN84426.1 - 0.13 10.3 0.1 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Menin Nbl1_Borealin_N PF10444.4 KZN84427.1 - 2.9e-20 71.3 4.5 2.9e-20 71.3 3.1 1.7 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 KZN84428.1 - 3.8e-10 40.1 0.1 5.1e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KZN84428.1 - 1.3e-05 24.8 0.1 1.9e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KZN84428.1 - 0.0024 17.2 0.5 0.0095 15.4 0.3 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA PF00092.23 KZN84428.1 - 0.0029 17.3 0.5 0.0048 16.6 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sybindin PF04099.7 KZN84429.1 - 9.3e-47 158.3 0.0 1.9e-46 157.2 0.0 1.5 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KZN84429.1 - 3e-08 33.6 0.0 8.1e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region ABC2_membrane PF01061.19 KZN84430.1 - 3.5e-83 277.8 65.2 9.6e-46 155.5 18.5 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN84430.1 - 4.9e-36 124.0 0.0 1.6e-16 60.8 0.0 3.4 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.7 KZN84430.1 - 6e-31 106.1 13.7 8.9e-31 105.6 0.0 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 KZN84430.1 - 5.4e-23 80.8 0.1 1.1e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KZN84430.1 - 5.1e-05 22.7 0.5 0.016 14.6 0.2 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN84430.1 - 0.0011 18.1 0.1 0.031 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KZN84430.1 - 0.0032 17.3 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN84430.1 - 0.0038 17.5 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KZN84430.1 - 0.0064 15.9 0.6 0.072 12.5 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KZN84430.1 - 0.01 15.3 0.7 0.71 9.4 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KZN84430.1 - 0.012 14.6 45.5 0.01 14.9 14.0 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein SMC_N PF02463.14 KZN84430.1 - 0.019 14.2 0.0 2.1 7.5 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KZN84430.1 - 0.029 14.0 0.7 12 5.5 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.1 KZN84430.1 - 0.043 13.9 0.1 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KZN84430.1 - 0.051 14.0 0.0 8.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KZN84430.1 - 0.11 12.1 0.3 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN84430.1 - 0.11 13.2 0.0 2.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KZN84430.1 - 0.12 12.3 0.6 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KZN84430.1 - 0.61 10.3 0.0 1.4 9.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arylsulfotran_2 PF14269.1 KZN84431.1 - 7.1e-75 251.9 0.4 1.1e-74 251.3 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN84431.1 - 1.1e-14 53.8 0.0 2.3e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 KZN84432.1 - 4.8e-42 143.9 43.7 4.8e-42 143.9 30.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84432.1 - 3.9e-13 48.7 34.7 1e-12 47.3 12.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Alpha-L-AF_C PF06964.7 KZN84433.1 - 2.4e-34 118.6 0.0 4.4e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KZN84433.1 - 0.1 12.6 0.7 0.28 11.2 0.5 1.8 1 1 0 1 1 1 0 Carbohydrate binding domain PA_decarbox PF05870.6 KZN84434.1 - 1.1e-09 37.9 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Bac_rhamnosid PF05592.6 KZN84435.1 - 8.4e-33 113.3 1.3 4.7e-27 94.3 1.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 KZN84435.1 - 3.4e-05 22.6 1.1 4.8e-05 22.1 0.8 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 KZN84435.1 - 0.00021 20.1 2.5 0.00039 19.2 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 TPR_12 PF13424.1 KZN84436.1 - 9.1e-38 128.0 0.0 1.1e-12 47.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 KZN84436.1 - 1.2e-30 104.4 0.0 1e-05 25.2 0.0 7.8 9 0 0 9 9 9 4 Tetratricopeptide repeat Patatin PF01734.17 KZN84436.1 - 4e-20 72.6 0.0 1.3e-19 70.9 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.1 KZN84436.1 - 2.8e-12 46.1 0.2 0.0028 17.2 0.0 4.7 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 KZN84436.1 - 2.2e-11 42.7 0.1 0.23 11.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 KZN84436.1 - 1.3e-10 40.5 0.2 2.5e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 KZN84436.1 - 1.4e-07 30.7 0.9 1.4 8.9 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84436.1 - 3e-07 29.7 0.3 0.31 10.7 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NACHT PF05729.7 KZN84436.1 - 1.4e-06 28.1 0.1 4.4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain TPR_19 PF14559.1 KZN84436.1 - 2.3e-06 27.8 0.0 0.12 12.7 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84436.1 - 8.1e-06 26.3 0.0 0.89 10.3 0.2 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84436.1 - 1.9e-05 24.9 0.0 12 6.8 0.0 6.4 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84436.1 - 2.2e-05 23.8 0.4 3 7.8 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.9 KZN84436.1 - 6.9e-05 22.1 0.7 0.019 14.1 0.0 3.1 3 1 0 3 3 3 1 Coatomer epsilon subunit IstB_IS21 PF01695.12 KZN84436.1 - 0.00072 19.0 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KZN84436.1 - 0.0009 19.3 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.1 KZN84436.1 - 0.074 13.5 1.3 87 3.9 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 KZN84436.1 - 0.093 12.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) SH3BGR PF04908.10 KZN84439.1 - 0.00035 20.4 0.0 0.0014 18.5 0.0 2.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Carboxyl_trans PF01039.17 KZN84439.1 - 0.024 12.9 0.1 0.044 12.1 0.1 1.5 1 0 0 1 1 1 0 Carboxyl transferase domain DUF4193 PF13834.1 KZN84439.1 - 5.7 7.1 8.6 3.6 7.8 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Ribul_P_3_epim PF00834.14 KZN84440.1 - 4.3e-62 208.7 0.0 6.9e-61 204.8 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 KZN84440.1 - 0.054 12.8 0.1 0.098 12.0 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_11 PF08241.7 KZN84441.1 - 1.9e-07 31.4 0.0 3.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84441.1 - 0.00062 19.5 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain LSM PF01423.17 KZN84442.1 - 4.8e-15 54.8 0.6 6.9e-15 54.3 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN84442.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DRMBL PF07522.9 KZN84443.1 - 4.5e-33 113.5 0.0 8.8e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KZN84443.1 - 2.9e-10 40.0 0.0 6.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TIP49 PF06068.8 KZN84443.1 - 0.21 10.2 0.2 0.32 9.6 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Abhydrolase_6 PF12697.2 KZN84444.1 - 1.1e-16 61.4 0.0 1.9e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84444.1 - 2.4e-09 37.1 0.1 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN84444.1 - 3.5e-05 23.4 0.0 6.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 KZN84445.1 - 6.4e-102 341.4 0.0 7.7e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.10 KZN84446.1 - 4e-185 616.8 58.4 4.6e-185 616.6 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zn_clus PF00172.13 KZN84447.1 - 6.3e-07 29.1 7.5 6.3e-07 29.1 5.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN84447.1 - 1.7e-06 27.1 0.4 2.8e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMP PF04927.7 KZN84448.1 - 1.6e-13 50.3 17.2 0.00026 20.8 1.5 3.1 2 1 1 3 3 3 3 Seed maturation protein GFA PF04828.9 KZN84449.1 - 1.2e-22 79.6 0.0 1.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KZN84449.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal NMD3 PF04981.8 KZN84449.1 - 0.16 11.0 0.7 0.61 9.1 0.3 1.8 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 KZN84449.1 - 0.38 10.6 3.1 1.2 8.9 1.1 2.4 2 1 0 2 2 2 0 Double zinc ribbon Citrate_synt PF00285.16 KZN84450.1 - 1.8e-68 230.8 0.0 2.1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase MFS_1 PF07690.11 KZN84451.1 - 1.2e-43 149.2 28.6 1.9e-43 148.5 19.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PBP PF01161.15 KZN84451.1 - 5.5e-14 52.2 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TRI12 PF06609.8 KZN84451.1 - 5.1e-05 21.6 3.9 5.1e-05 21.6 2.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KZN84451.1 - 0.00096 17.3 4.8 0.00096 17.3 3.3 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 KZN84451.1 - 0.0045 16.7 3.3 0.0066 16.2 0.3 2.9 3 0 0 3 3 3 1 MFS_1 like family Zn_clus PF00172.13 KZN84452.1 - 2.3e-08 33.8 5.6 5.1e-08 32.6 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.15 KZN84453.1 - 1.5e-21 76.7 0.0 1.7e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Epimerase PF01370.16 KZN84454.1 - 1.1e-07 31.5 0.2 5.8e-07 29.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN84454.1 - 6.2e-06 26.3 0.1 8.6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN84454.1 - 9.6e-06 25.0 0.2 2.2e-05 23.8 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KZN84454.1 - 2.4e-05 23.1 0.2 0.00077 18.2 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KZN84454.1 - 0.016 15.2 0.3 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain ATG22 PF11700.3 KZN84455.1 - 8.6e-185 614.7 12.6 9.8e-185 614.5 8.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KZN84455.1 - 0.045 12.4 54.9 0.032 12.9 7.1 3.5 2 1 1 3 3 3 0 Major Facilitator Superfamily IncA PF04156.9 KZN84455.1 - 0.059 12.9 0.8 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 IncA protein DUF973 PF06157.6 KZN84455.1 - 0.83 8.5 9.6 0.064 12.2 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Sugar_tr PF00083.19 KZN84459.1 - 6.7e-75 252.3 30.4 7.7e-75 252.1 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84459.1 - 1.1e-19 70.3 38.8 7.3e-18 64.3 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KZN84459.1 - 0.015 14.5 1.8 0.062 12.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF21 Stap_Strp_toxin PF01123.15 KZN84459.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain F-box-like PF12937.2 KZN84460.1 - 0.049 13.3 0.3 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like DUF4418 PF14387.1 KZN84461.1 - 2.8 7.6 12.8 0.18 11.5 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Dioxygenase_C PF00775.16 KZN84462.1 - 2.8e-12 46.2 0.2 4.6e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase MFS_1 PF07690.11 KZN84463.1 - 1.1e-25 90.1 32.9 1.1e-25 90.1 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN84463.1 - 7.8e-06 24.3 1.9 1.4e-05 23.5 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.1 KZN84464.1 - 2.9e-31 109.0 0.0 3.3e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN84464.1 - 2.7e-30 105.4 0.1 3.4e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84464.1 - 2.5e-17 63.1 0.1 3.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.19 KZN84466.1 - 6.8e-93 311.6 29.0 8e-93 311.4 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84466.1 - 2.3e-23 82.4 27.5 2.3e-23 82.4 19.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN84466.1 - 1.6e-05 23.3 1.5 1.6e-05 23.3 1.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KZN84467.1 - 4.1e-45 154.0 36.3 5.2e-45 153.6 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84467.1 - 3.5e-19 68.7 16.4 8.8e-19 67.4 11.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KZN84467.1 - 2.4 6.1 18.3 4.3 5.2 6.6 3.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aa_trans PF01490.13 KZN84468.1 - 1.4e-39 135.7 35.3 1.7e-39 135.5 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KZN84469.1 - 1.7e-48 165.2 45.6 2.1e-48 164.9 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84469.1 - 7.7e-25 87.1 38.7 9.8e-25 86.8 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease DivIVA PF05103.8 KZN84470.1 - 0.043 13.8 2.0 0.063 13.3 1.4 1.2 1 0 0 1 1 1 0 DivIVA protein DUF1275 PF06912.6 KZN84471.1 - 3.2e-35 121.2 17.3 4e-35 120.9 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.17 KZN84472.1 - 1.1e-31 109.1 0.0 1.9e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KZN84472.1 - 4e-25 87.0 0.8 2e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KZN84472.1 - 3.4e-10 39.1 0.0 2.8e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KZN84472.1 - 1.3e-06 28.1 0.2 0.00057 19.5 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KZN84472.1 - 0.0033 17.0 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 Cupin Glyco_hydro_31 PF01055.21 KZN84476.1 - 3.2e-50 171.2 8.8 4.3e-50 170.8 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AA_permease_2 PF13520.1 KZN84477.1 - 7.6e-77 258.6 38.9 9.3e-77 258.3 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84477.1 - 4.2e-20 71.5 35.9 5.4e-20 71.1 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3092 PF11289.3 KZN84477.1 - 0.014 14.6 3.1 0.027 13.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Glyco_hydro_92 PF07971.7 KZN84478.1 - 3.6e-141 471.2 9.0 4.6e-141 470.9 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 UPRTase PF14681.1 KZN84479.1 - 3.5e-40 137.4 0.1 7.3e-40 136.3 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 KZN84479.1 - 2.4e-06 27.8 0.1 1.3e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 KZN84479.1 - 1e-05 26.3 0.0 2.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 KZN84479.1 - 0.00018 21.2 0.6 0.0024 17.5 0.4 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_18 PF13238.1 KZN84479.1 - 0.004 17.4 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN84479.1 - 0.0056 15.8 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin PRTase_2 PF15609.1 KZN84479.1 - 0.0056 15.9 0.2 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase AAA_16 PF13191.1 KZN84479.1 - 0.011 15.7 0.0 0.42 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain KAP_NTPase PF07693.9 KZN84479.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Hydrolase_3 PF08282.7 KZN84479.1 - 0.061 12.8 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_U4 PF03419.8 KZN84479.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA AAA_22 PF13401.1 KZN84479.1 - 0.12 12.5 0.2 0.64 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.5 KZN84479.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_M50B PF13398.1 KZN84481.1 - 2e-56 190.5 21.6 2.5e-56 190.2 15.0 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KZN84481.1 - 0.004 16.1 0.3 0.004 16.1 0.2 2.6 2 1 1 3 3 3 1 Peptidase family M50 SecD_SecF PF02355.11 KZN84481.1 - 0.052 12.7 0.3 0.052 12.7 0.2 2.7 4 0 0 4 4 4 0 Protein export membrane protein Peptidase_M41 PF01434.13 KZN84481.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.13 KZN84481.1 - 1.6 6.5 7.1 2.6 5.8 4.9 1.3 1 0 0 1 1 1 0 Patched family MLANA PF14991.1 KZN84481.1 - 8.3 6.4 9.2 2.4 8.1 1.1 2.4 1 1 1 2 2 2 0 Protein melan-A GvpK PF05121.7 KZN84482.1 - 0.041 13.7 0.1 23 4.9 0.0 3.0 2 1 1 3 3 3 0 Gas vesicle protein K Yippee-Mis18 PF03226.9 KZN84482.1 - 0.22 11.6 1.5 0.47 10.5 1.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Beta_elim_lyase PF01212.16 KZN84483.1 - 3.7e-68 229.7 0.0 4.5e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KZN84483.1 - 0.00083 18.0 0.0 0.0015 17.1 0.0 1.3 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 KZN84483.1 - 0.00099 17.4 0.0 0.0016 16.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 KZN84484.1 - 3.5e-69 232.8 0.0 5.1e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84484.1 - 1.1e-33 116.4 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KZN84484.1 - 3.9e-11 42.9 0.2 1.2e-10 41.3 0.3 1.8 2 0 0 2 2 2 1 FHA domain APH PF01636.18 KZN84484.1 - 2.4e-05 24.2 0.5 0.034 13.8 0.0 3.0 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN84484.1 - 0.00011 21.3 0.2 0.00021 20.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN84484.1 - 0.0011 17.9 0.0 0.0043 16.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KZN84484.1 - 0.11 11.8 0.3 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KZN84484.1 - 0.2 10.4 0.1 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_transf_34 PF05637.7 KZN84485.1 - 3.3e-62 210.1 0.5 4.4e-62 209.6 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 KZN84486.1 - 0.0034 17.5 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 KZN84487.1 - 1.5e-06 27.1 0.0 2.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Glyco_hydro_16 PF00722.16 KZN84489.1 - 9.4e-22 77.1 1.2 1e-13 51.0 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 KZN84490.1 - 1.6e-36 125.3 4.6 2.9e-36 124.4 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Bromo_TP PF07524.8 KZN84491.1 - 1.5e-06 27.8 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated AstB PF04996.7 KZN84491.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Succinylarginine dihydrolase TAFII55_N PF04658.8 KZN84492.1 - 2.8e-51 173.2 0.7 5.6e-51 172.2 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region Epimerase PF01370.16 KZN84494.1 - 4.6e-13 49.1 0.0 5.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN84494.1 - 5.9e-13 48.1 0.0 7.9e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN84494.1 - 1.9e-11 44.3 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN84494.1 - 4.2e-09 35.6 0.0 1.1e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KZN84494.1 - 5.5e-05 22.5 0.0 0.00023 20.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KZN84494.1 - 0.00073 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 KZN84494.1 - 0.036 13.9 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KZN84494.1 - 0.079 11.8 0.0 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 KZN84494.1 - 0.11 12.3 0.3 0.78 9.6 0.2 2.3 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.21 KZN84495.1 - 3.7e-25 87.9 0.1 6.2e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN84495.1 - 5.2e-22 77.6 0.9 1.1e-21 76.5 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN84495.1 - 0.00048 21.0 0.0 0.0013 19.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.8 KZN84495.1 - 0.036 13.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain EthD PF07110.6 KZN84496.1 - 2.3e-12 47.6 0.5 3.4e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 EthD domain Dicer_dimer PF03368.9 KZN84496.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Dicer dimerisation domain ECH PF00378.15 KZN84497.1 - 1.1e-20 73.8 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KZN84497.1 - 0.006 16.3 0.0 1.6 8.4 0.0 2.4 2 1 0 2 2 2 2 Peptidase family S49 DUF3880 PF12996.2 KZN84498.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DUF4291 PF14124.1 KZN84500.1 - 9e-78 260.0 0.0 1e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) TelA PF05816.6 KZN84501.1 - 0.099 11.3 0.7 0.15 10.7 0.5 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Ofd1_CTDD PF10637.4 KZN84502.1 - 1.2e-101 339.3 0.2 9.1e-95 316.7 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KZN84502.1 - 3.8e-16 59.4 0.0 8.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KZN84502.1 - 0.016 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily HLH PF00010.21 KZN84504.1 - 4e-14 52.0 0.5 1e-13 50.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ig PF00047.20 KZN84504.1 - 0.073 13.2 0.7 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Immunoglobulin domain DUF805 PF05656.9 KZN84505.1 - 0.039 13.7 0.2 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Tetraspannin PF00335.15 KZN84505.1 - 0.41 9.8 0.0 0.73 9.0 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Phosphodiest PF01663.17 KZN84507.1 - 1.7e-90 303.9 0.1 2.1e-90 303.6 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KZN84507.1 - 0.0002 20.6 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 2 Sulfatase PRCC PF10253.4 KZN84507.1 - 6.2 7.4 6.7 2.7 8.6 2.9 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting WD40 PF00400.27 KZN84508.1 - 6.8e-69 225.4 19.3 5e-13 48.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.20 KZN84508.1 - 1.2e-35 122.9 0.0 1.6e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84508.1 - 1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasome_A_N PF10584.4 KZN84508.1 - 6.7e-14 50.9 0.9 0.3 10.4 0.0 6.7 7 0 0 7 7 7 5 Proteasome subunit A N-terminal signature eIF2A PF08662.6 KZN84508.1 - 2.4e-09 37.1 0.1 0.021 14.5 0.0 3.3 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KZN84508.1 - 1.4e-08 33.3 2.4 0.0012 17.0 0.0 4.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 KZN84508.1 - 2.5e-08 33.4 1.6 6 6.6 0.0 7.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KZN84508.1 - 1.3e-07 30.2 0.0 0.045 12.0 0.0 3.5 2 1 2 4 4 4 4 Cytochrome D1 heme domain B_lectin PF01453.19 KZN84508.1 - 2.8e-07 30.4 13.5 0.048 13.5 0.8 4.7 2 1 2 5 5 5 3 D-mannose binding lectin TruB_C PF09142.6 KZN84508.1 - 5.2e-06 26.0 0.1 23 4.7 0.0 6.0 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal Gmad1 PF10647.4 KZN84508.1 - 5.4e-06 25.9 9.4 0.0028 17.1 1.1 4.3 2 1 3 5 5 5 3 Lipoprotein LpqB beta-propeller domain DUF1513 PF07433.6 KZN84508.1 - 8.4e-05 21.6 2.0 0.094 11.5 0.0 3.5 2 2 2 4 4 4 1 Protein of unknown function (DUF1513) IKI3 PF04762.7 KZN84508.1 - 0.00083 17.3 0.0 0.8 7.4 0.0 2.7 1 1 0 2 2 2 2 IKI3 family SoxG PF04268.7 KZN84508.1 - 0.0058 16.4 0.2 0.56 10.0 0.0 3.0 1 1 2 3 3 3 1 Sarcosine oxidase, gamma subunit family Kdo PF06293.9 KZN84508.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1258 PF06869.7 KZN84508.1 - 0.099 11.7 2.2 36 3.3 0.0 4.3 2 2 4 6 6 6 0 Protein of unknown function (DUF1258) BCS1_N PF08740.6 KZN84510.1 - 1.7e-51 174.4 1.3 2.8e-51 173.7 0.9 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KZN84510.1 - 2e-18 66.8 0.0 3.5e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN84510.1 - 0.00037 21.2 0.5 0.0017 19.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KZN84510.1 - 0.0032 17.4 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KZN84510.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN84510.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 KZN84510.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KZN84510.1 - 0.04 14.2 0.2 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KZN84510.1 - 0.073 12.7 0.0 0.46 10.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Glyco_hydro_43 PF04616.9 KZN84511.1 - 4e-33 114.7 0.0 5.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KZN84511.1 - 0.48 9.7 3.0 0.44 9.8 0.3 2.1 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_31 PF01055.21 KZN84512.1 - 4.5e-94 315.7 9.6 6e-94 315.3 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN84512.1 - 4.9e-05 23.1 0.2 0.0002 21.1 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF3533 PF12051.3 KZN84513.1 - 2.2e-98 329.5 11.7 2.9e-98 329.1 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) CRF-BP PF05428.6 KZN84513.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Pkinase PF00069.20 KZN84514.1 - 4.2e-07 29.3 0.0 7.9e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84514.1 - 0.033 13.2 0.0 0.08 12.0 0.0 1.7 1 1 1 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 KZN84515.1 - 4.4e-13 48.9 0.0 9.7e-12 44.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84515.1 - 8.2e-06 25.0 0.0 0.00017 20.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN84515.1 - 0.0005 19.1 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN84515.1 - 0.046 13.4 0.4 0.62 9.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family BNIP2 PF12496.3 KZN84516.1 - 5 7.3 7.4 8.1 6.6 4.9 1.4 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RibD_C PF01872.12 KZN84517.1 - 4.1e-32 111.4 0.0 4.7e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DUF718 PF05336.8 KZN84517.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF718) Ank_2 PF12796.2 KZN84518.1 - 6e-50 167.5 0.8 1.6e-16 60.3 0.0 4.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84518.1 - 1.8e-28 96.8 11.0 0.0003 20.4 0.1 8.1 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 KZN84518.1 - 2.9e-26 88.9 2.0 0.0044 17.1 0.0 8.1 7 1 1 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KZN84518.1 - 1e-20 73.6 0.9 1.8e-07 31.4 0.0 5.9 4 1 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN84518.1 - 4.3e-18 64.9 4.0 0.0049 17.0 0.1 7.7 3 3 5 8 8 8 7 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN84518.1 - 0.00014 21.5 1.7 0.00023 20.8 1.2 1.4 1 0 0 1 1 1 1 F-box-like Dyp_perox PF04261.7 KZN84520.1 - 6.5e-12 44.8 0.0 9.5e-10 37.7 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family DUF1796 PF08795.5 KZN84520.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Glyco_hydro_11 PF00457.12 KZN84523.1 - 5.1e-76 254.0 22.2 5.9e-76 253.8 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sulfate_transp PF00916.15 KZN84524.1 - 5.5e-69 232.2 8.2 5.5e-69 232.2 5.7 2.4 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KZN84524.1 - 7.2e-31 105.7 3.1 7.2e-31 105.7 2.2 3.8 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KZN84524.1 - 4.8e-08 32.4 0.0 1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KZN84524.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 STAS domain SNN_transmemb PF09049.5 KZN84524.1 - 0.028 14.0 0.9 0.028 14.0 0.6 3.4 3 0 0 3 3 3 0 Stannin transmembrane Glyco_transf_90 PF05686.7 KZN84525.1 - 1.9e-31 109.1 0.0 2.7e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KZN84525.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.18 KZN84526.1 - 4.1e-111 370.9 0.0 6.1e-111 370.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KZN84526.1 - 9.4e-43 145.2 0.2 2.1e-42 144.1 0.2 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KZN84526.1 - 8.8e-08 32.3 0.0 2.9e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 KZN84526.1 - 3.3e-07 30.2 0.2 8.9e-07 28.8 0.2 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KZN84526.1 - 1e-05 25.5 0.0 0.00011 22.2 0.0 2.7 2 0 0 2 2 2 1 FHA domain DUF4407 PF14362.1 KZN84526.1 - 0.05 12.5 0.5 0.13 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.8 KZN84526.1 - 1.2 8.8 6.7 8.5 6.2 1.0 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal LPP PF04728.8 KZN84527.1 - 4.8e-05 23.0 0.8 0.067 12.9 0.5 3.0 3 0 0 3 3 3 2 Lipoprotein leucine-zipper IFT20 PF14931.1 KZN84527.1 - 0.011 15.5 1.4 0.013 15.3 0.3 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3826 PF12875.2 KZN84527.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) NPV_P10 PF05531.7 KZN84527.1 - 0.025 14.8 0.3 9.1 6.6 0.6 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HEPN PF05168.9 KZN84527.1 - 0.027 14.3 0.0 7.4 6.4 0.0 2.6 2 1 1 3 3 3 0 HEPN domain Reo_sigmaC PF04582.7 KZN84527.1 - 0.028 13.6 0.3 0.034 13.3 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_I PF06008.9 KZN84527.1 - 0.028 13.7 1.6 0.075 12.3 0.8 1.7 1 1 1 2 2 2 0 Laminin Domain I ADIP PF11559.3 KZN84527.1 - 0.034 14.0 1.2 1.2 9.0 0.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KZN84527.1 - 0.037 13.8 1.4 3.3 7.5 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.3 KZN84527.1 - 0.049 13.3 0.6 0.2 11.3 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) ydhR PF08803.6 KZN84527.1 - 0.11 12.5 0.1 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR Cep57_MT_bd PF06657.8 KZN84527.1 - 0.16 11.9 1.2 2.4 8.1 0.2 3.0 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 PspB PF06667.7 KZN84527.1 - 0.2 11.6 2.3 23 5.0 0.0 3.2 2 1 1 3 3 3 0 Phage shock protein B Syntaxin PF00804.20 KZN84527.1 - 0.27 11.4 2.1 1.4 9.1 0.3 2.2 1 1 1 2 2 2 0 Syntaxin DUF948 PF06103.6 KZN84527.1 - 0.76 9.6 4.2 2.2 8.1 0.1 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 KZN84527.1 - 1.3 9.1 4.5 14 5.9 0.3 3.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CBFB_NFYA PF02045.10 KZN84528.1 - 1.2e-30 105.8 4.1 2.3e-30 104.9 2.9 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 KZN84528.1 - 0.043 12.7 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein FAM163 PF15069.1 KZN84528.1 - 6.4 7.3 5.9 1.4 9.4 0.3 2.4 1 1 1 3 3 3 0 FAM163 family DUF3546 PF12066.3 KZN84530.1 - 9.1e-25 86.8 1.5 9.1e-25 86.8 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KZN84530.1 - 3.5e-23 80.9 0.1 8e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KZN84530.1 - 1.1e-11 45.4 1.6 1.7e-11 44.7 0.2 2.0 1 1 1 2 2 2 1 Arsenite-resistance protein 2 Cnd1_N PF12922.2 KZN84530.1 - 0.6 9.7 3.3 2.7 7.6 0.9 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term bZIP_1 PF00170.16 KZN84532.1 - 0.0029 17.5 11.7 0.0096 15.8 8.1 1.8 1 1 0 1 1 1 1 bZIP transcription factor AAA_13 PF13166.1 KZN84532.1 - 0.086 11.2 0.6 0.12 10.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 KZN84532.1 - 0.35 10.7 10.4 0.056 13.2 3.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper eIF-3_zeta PF05091.7 KZN84533.1 - 3e-191 636.5 0.0 3.5e-191 636.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ank_2 PF12796.2 KZN84534.1 - 1.2e-25 89.6 0.3 1.6e-17 63.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84534.1 - 3.1e-22 77.2 3.5 4e-07 29.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KZN84534.1 - 1.2e-18 66.7 7.1 6.8e-14 51.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN84534.1 - 2.8e-18 65.8 0.8 5.7e-11 42.6 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN84534.1 - 5.4e-16 57.1 1.4 0.00011 22.1 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeat CMD PF02627.15 KZN84535.1 - 9.2e-19 67.0 0.1 1.5e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_9 PF13454.1 KZN84536.1 - 2.6e-45 153.9 0.0 5e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding ThiF PF00899.16 KZN84536.1 - 0.12 12.2 0.1 7.4 6.3 0.0 2.9 3 0 0 3 3 3 0 ThiF family HMG_CoA_synt_C PF08540.5 KZN84537.1 - 3.1e-98 328.7 0.8 3.7e-98 328.4 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KZN84537.1 - 5.1e-83 276.8 0.0 7.4e-83 276.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Hydrophobin PF01185.13 KZN84538.1 - 0.0002 21.7 2.5 0.00039 20.8 1.7 1.5 1 0 0 1 1 1 1 Fungal hydrophobin Clathrin_bdg PF15045.1 KZN84538.1 - 0.022 14.2 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Pkinase PF00069.20 KZN84539.1 - 8e-12 44.8 0.1 5.3e-08 32.3 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84539.1 - 1.7e-07 30.5 0.2 0.00012 21.2 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase HD_3 PF13023.1 KZN84540.1 - 2.6e-10 40.2 0.9 4.7e-10 39.4 0.6 1.4 1 0 0 1 1 1 1 HD domain ADK PF00406.17 KZN84540.1 - 1.3e-06 28.3 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KZN84540.1 - 5.4e-05 23.4 0.2 0.00017 21.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Pkinase PF00069.20 KZN84541.1 - 3e-13 49.5 0.0 4.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84541.1 - 1.3e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN84541.1 - 2.1e-06 27.6 0.3 3.5e-06 26.9 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN84541.1 - 0.0001 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KZN84541.1 - 0.00016 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KZN84541.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 KZN84541.1 - 0.081 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zn_clus PF00172.13 KZN84542.1 - 2.1e-13 49.9 34.1 6.6e-07 29.1 9.3 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN84542.1 - 1.9e-09 36.7 2.5 1.9e-09 36.7 1.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KZN84543.1 - 3.8e-66 223.3 0.2 5.2e-66 222.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN84543.1 - 3.6e-07 29.8 6.4 2.2e-06 27.2 4.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN84543.1 - 0.039 12.3 0.0 0.076 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 KZN84543.1 - 0.049 13.9 0.1 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 KZN84544.1 - 8.7e-72 242.1 23.0 9.9e-72 241.9 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84544.1 - 3.7e-13 48.9 36.9 3.7e-13 48.9 25.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN84544.1 - 5.4e-06 25.0 3.7 5.4e-06 25.0 2.6 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Cupin_1 PF00190.17 KZN84545.1 - 5.1e-27 94.0 0.0 5.7e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KZN84545.1 - 4.6e-23 80.4 0.4 3.3e-12 45.7 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KZN84545.1 - 1e-09 37.6 0.0 0.00056 19.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KZN84545.1 - 2.8e-07 30.2 0.0 0.00048 19.8 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KZN84545.1 - 8.3e-05 22.2 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.13 KZN84545.1 - 0.0016 18.0 0.0 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 KZN84545.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 KZN84545.1 - 0.027 14.4 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family FdtA PF05523.6 KZN84545.1 - 0.034 13.6 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 WxcM-like, C-terminal Cupin_4 PF08007.7 KZN84545.1 - 0.035 13.3 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.1 KZN84545.1 - 0.045 14.0 0.6 75 3.6 0.0 3.5 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase DUF1971 PF09313.6 KZN84545.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) MFS_1 PF07690.11 KZN84546.1 - 4.8e-23 81.4 24.2 1.8e-19 69.7 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.6 KZN84546.1 - 0.00043 19.5 3.9 0.00062 18.9 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) Peptidase_M20 PF01546.23 KZN84547.1 - 5.8e-10 38.9 0.1 9.5e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN84547.1 - 5e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KZN84548.1 - 1.5e-12 46.8 1.9 3.5e-11 42.3 1.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 KZN84549.1 - 1.4e-42 145.0 0.7 7.9e-14 51.9 0.0 5.2 6 0 0 6 6 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 KZN84549.1 - 1.2e-40 139.0 0.0 1.6e-39 135.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KZN84549.1 - 1.9e-26 93.0 20.6 7.4e-25 87.8 0.0 6.4 5 1 0 5 5 5 1 AAA domain AAA_19 PF13245.1 KZN84549.1 - 1.1e-18 66.7 1.4 2.1e-07 30.5 0.0 5.1 4 0 0 4 4 4 4 Part of AAA domain AAA_5 PF07728.9 KZN84549.1 - 1.1e-13 51.0 0.4 0.057 13.1 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN84549.1 - 3.6e-13 49.7 5.0 0.029 14.5 0.0 7.0 4 3 0 4 4 4 3 AAA domain AAA_30 PF13604.1 KZN84549.1 - 1.1e-12 47.9 0.1 4.8e-05 23.0 0.0 6.2 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 KZN84549.1 - 5.7e-12 46.5 10.6 0.015 16.0 0.0 5.8 6 0 0 6 6 4 4 AAA domain IstB_IS21 PF01695.12 KZN84549.1 - 3.2e-10 39.7 0.0 0.032 13.6 0.0 5.0 4 0 0 4 4 4 3 IstB-like ATP binding protein Mg_chelatase PF01078.16 KZN84549.1 - 7.1e-09 35.1 0.6 0.29 10.2 0.0 4.9 5 0 0 5 5 5 3 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KZN84549.1 - 3.1e-08 33.9 8.0 0.11 12.8 0.0 6.4 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.1 KZN84549.1 - 3.4e-08 33.6 14.4 0.026 14.4 0.0 6.2 6 0 0 6 6 5 3 AAA ATPase domain RNA_helicase PF00910.17 KZN84549.1 - 4.1e-08 33.3 0.1 0.46 10.6 0.0 4.8 4 0 0 4 4 4 1 RNA helicase AAA_24 PF13479.1 KZN84549.1 - 4e-05 23.2 4.4 2.9 7.4 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KZN84549.1 - 4.3e-05 23.0 1.2 0.1 11.9 0.0 4.4 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.4 KZN84549.1 - 0.00011 21.3 8.8 0.00055 19.0 0.0 5.3 6 1 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KZN84549.1 - 0.00011 22.2 4.1 3.8 7.4 0.1 5.0 4 0 0 4 4 4 1 AAA domain PhoH PF02562.11 KZN84549.1 - 0.00035 19.8 0.1 0.89 8.7 0.0 4.3 4 0 0 4 4 4 1 PhoH-like protein SKI PF01202.17 KZN84549.1 - 0.0019 18.0 2.2 12 5.7 0.0 5.1 4 0 0 4 4 4 0 Shikimate kinase AAA_33 PF13671.1 KZN84549.1 - 0.009 15.8 15.3 1.8 8.4 0.0 5.2 6 0 0 6 6 4 2 AAA domain NACHT PF05729.7 KZN84549.1 - 0.0098 15.5 0.8 9.5 5.8 0.0 4.2 4 0 0 4 4 4 0 NACHT domain KaiC PF06745.8 KZN84549.1 - 0.044 12.8 3.3 2.7 7.0 0.0 3.9 4 0 0 4 4 4 0 KaiC Adeno_IVa2 PF02456.10 KZN84549.1 - 0.063 11.9 0.0 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein zf-NF-X1 PF01422.12 KZN84549.1 - 1.7 8.6 9.7 4.9 7.1 6.7 1.9 1 0 0 1 1 1 0 NF-X1 type zinc finger Pet127 PF08634.5 KZN84550.1 - 0.16 11.1 0.0 0.41 9.7 0.0 1.7 1 1 1 2 2 2 0 Mitochondrial protein Pet127 WD40 PF00400.27 KZN84551.1 - 9.1e-75 244.1 18.6 2.3e-12 46.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KZN84551.1 - 0.00036 18.8 2.6 0.34 8.9 0.0 4.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KZN84551.1 - 0.012 14.3 1.4 3.6 6.2 0.0 3.9 2 1 2 4 4 4 0 Nup133 N terminal like LisH PF08513.6 KZN84551.1 - 0.018 14.7 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 LisH Ribonuclease_3 PF00636.21 KZN84553.1 - 1e-07 32.3 0.0 3.4e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN84553.1 - 3.1e-05 23.9 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like TFR_dimer PF04253.10 KZN84553.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain CSTF_C PF14304.1 KZN84554.1 - 0.011 14.9 2.3 0.019 14.2 1.6 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Abhydro_lipase PF04083.11 KZN84555.1 - 9.3e-21 72.9 0.0 2e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KZN84555.1 - 2.7e-06 27.4 2.0 5.6e-06 26.3 1.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN84555.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN84555.1 - 0.037 13.5 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNA_pol_Rpb1_R PF05001.8 KZN84555.1 - 4.1 7.7 7.1 16 5.9 4.9 2.1 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat MFS_1 PF07690.11 KZN84556.1 - 3.1e-40 137.9 53.8 1.3e-38 132.6 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1418 PF07214.7 KZN84556.1 - 0.0078 15.8 0.0 0.061 12.9 0.0 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) Arylsulfotran_2 PF14269.1 KZN84557.1 - 4.2e-120 400.4 0.2 5.3e-120 400.0 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Glyco_hydro_43 PF04616.9 KZN84558.1 - 4.7e-32 111.2 4.3 8.1e-32 110.4 3.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 SPRY PF00622.23 KZN84558.1 - 0.042 13.9 0.2 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 SPRY domain Glyco_hydro_3 PF00933.16 KZN84559.1 - 1.3e-45 155.7 0.0 1.5e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Cation_efflux PF01545.16 KZN84560.1 - 1.4e-80 270.4 0.0 2.4e-80 269.6 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 KZN84560.1 - 0.022 13.7 10.0 0.071 12.1 6.9 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1840 PF08895.6 KZN84560.1 - 0.1 12.5 0.4 0.54 10.3 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Metallophos PF00149.23 KZN84561.1 - 1.1e-10 41.2 0.8 3.4e-09 36.3 0.6 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 KZN84562.1 - 2.2e-125 418.7 27.1 2.5e-125 418.5 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84562.1 - 2.6e-23 82.3 32.6 6.4e-16 58.0 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 KZN84562.1 - 0.1 12.9 0.2 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2530 PF10745.4 KZN84562.1 - 3.4 7.7 7.5 3.6 7.6 0.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HET PF06985.6 KZN84563.1 - 1.2e-10 41.7 0.4 1.1e-06 28.8 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Lipase_GDSL PF00657.17 KZN84564.1 - 4.7e-14 52.7 0.0 5.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KZN84564.1 - 6e-14 52.5 0.0 7.5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KZN84564.1 - 5.6e-06 26.2 0.1 1.2e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family PhyH PF05721.8 KZN84565.1 - 1.2e-15 58.1 0.0 1.5e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KZN84565.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Fungal_trans_2 PF11951.3 KZN84566.1 - 3e-10 39.2 4.2 6.4e-10 38.1 1.1 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sugar_tr PF00083.19 KZN84567.1 - 1.3e-113 380.0 23.6 1.6e-113 379.6 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84567.1 - 6.4e-29 100.7 40.3 4.9e-25 87.9 16.1 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_transf_28 PF03033.15 KZN84569.1 - 7.5e-21 74.3 0.0 4.1e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KZN84569.1 - 5.7e-05 21.8 0.0 9.2e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KZN84569.1 - 6.7e-05 22.6 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 KZN84569.1 - 0.0002 21.4 0.0 0.00066 19.7 0.0 1.9 2 0 0 2 2 2 1 ATG C terminal domain HDOD PF08668.7 KZN84571.1 - 0.16 11.2 0.1 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 HDOD domain DUF202 PF02656.10 KZN84573.1 - 7.9e-17 61.2 2.8 7.9e-17 61.2 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) GFA PF04828.9 KZN84574.1 - 8e-20 70.5 1.9 1.3e-19 69.9 1.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_11 PF08241.7 KZN84575.1 - 3.4e-14 53.0 0.0 6.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN84575.1 - 1.3e-13 50.7 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84575.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84575.1 - 2.8e-11 43.3 0.0 5e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN84575.1 - 2.9e-11 43.9 0.0 4.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84575.1 - 1.3e-08 35.1 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN84575.1 - 7.8e-07 28.6 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KZN84575.1 - 2.3e-06 27.6 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN84575.1 - 5.8e-06 25.5 0.0 9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KZN84575.1 - 6.3e-06 25.4 0.0 9.3e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 KZN84575.1 - 0.00022 20.6 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 KZN84575.1 - 0.0012 17.5 0.0 0.0023 16.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 KZN84575.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KZN84575.1 - 0.0038 16.4 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 KZN84575.1 - 0.0043 15.9 0.0 0.0075 15.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Pox_MCEL PF03291.11 KZN84575.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme CMAS PF02353.15 KZN84575.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KZN84575.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KZN84575.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW zf-DHHC PF01529.15 KZN84576.1 - 2.2e-37 128.1 1.6 4.3e-37 127.1 1.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KZN84576.1 - 0.021 14.5 0.4 0.051 13.3 0.3 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF4636 PF15468.1 KZN84576.1 - 0.022 14.1 2.1 0.027 13.9 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) Daxx PF03344.10 KZN84576.1 - 0.78 8.1 5.8 1.1 7.6 4.0 1.1 1 0 0 1 1 1 0 Daxx Family adh_short PF00106.20 KZN84577.1 - 6.3e-23 81.5 0.0 9.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84577.1 - 3.6e-22 79.3 0.0 4.7e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN84577.1 - 3.6e-07 30.0 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KZN84577.1 - 0.00046 19.4 0.0 0.0011 18.1 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 KZN84577.1 - 0.0084 16.3 0.3 0.043 14.0 0.4 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding OTCace PF00185.19 KZN84577.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_3 PF03447.11 KZN84578.1 - 0.059 13.7 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain HATPase_c PF02518.21 KZN84579.1 - 2.2e-12 46.6 0.4 3.9e-11 42.6 0.1 3.0 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KZN84579.1 - 7.5e-10 38.5 0.0 1.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KZN84579.1 - 2.1e-09 36.8 0.0 5.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF1295 PF06966.7 KZN84580.1 - 1.1e-34 119.7 0.0 1.6e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KZN84580.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KZN84580.1 - 0.00029 20.8 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 KZN84580.1 - 0.0027 17.8 0.0 0.0066 16.6 0.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family BPD_transp_1 PF00528.17 KZN84580.1 - 0.0035 16.8 0.1 0.0076 15.7 0.0 1.6 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ERG4_ERG24 PF01222.12 KZN84580.1 - 0.034 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family 2-Hacid_dh_C PF02826.14 KZN84582.1 - 2e-37 128.0 0.0 5.7e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN84582.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.13 KZN84582.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KZN84582.1 - 0.16 11.9 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KZN84582.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_7 PF13508.1 KZN84583.1 - 2.2e-12 46.9 0.0 4.8e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN84583.1 - 1.5e-10 40.9 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN84583.1 - 3.5e-07 30.3 0.0 2.5e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN84583.1 - 0.00011 22.0 0.1 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN84583.1 - 0.00049 19.9 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KZN84583.1 - 0.0042 16.8 0.0 0.045 13.4 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein CFEM PF05730.6 KZN84585.1 - 3.8e-06 26.6 8.9 7.3e-06 25.7 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_transf_28 PF03033.15 KZN84587.1 - 6e-22 77.9 0.2 7.5e-21 74.3 0.1 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KZN84587.1 - 0.00079 18.0 0.0 0.0027 16.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.10 KZN84587.1 - 0.055 12.7 0.1 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF2985 PF11204.3 KZN84588.1 - 2.2e-38 129.8 1.4 2.2e-38 129.8 1.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) PepSY_TM PF03929.11 KZN84588.1 - 0.019 15.3 1.8 0.019 15.3 1.3 3.2 3 0 0 3 3 3 0 PepSY-associated TM helix UPF0104 PF03706.8 KZN84588.1 - 0.052 12.8 3.3 0.99 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) DUF1469 PF07332.6 KZN84588.1 - 1.9 8.2 6.5 0.3 10.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF998 PF06197.8 KZN84588.1 - 6.6 6.0 11.0 0.083 12.1 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF998) MFS_1 PF07690.11 KZN84589.1 - 1.6e-45 155.3 48.5 1.1e-44 152.5 34.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN84589.1 - 2.3e-22 78.9 27.6 5.1e-22 77.8 19.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN84589.1 - 3.3e-15 55.6 9.9 3.3e-15 55.6 6.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.3 KZN84589.1 - 0.014 13.9 20.8 0.23 9.8 8.2 3.4 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like OATP PF03137.15 KZN84589.1 - 0.31 9.0 6.4 2.7 5.9 0.6 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.7 KZN84590.1 - 9.2e-31 105.8 3.9 1.7e-30 104.9 0.4 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN84590.1 - 1.9e-14 53.3 0.1 5.8e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN84590.1 - 0.0022 18.8 0.0 0.0066 17.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 KZN84590.1 - 0.0053 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN84590.1 - 0.0065 16.0 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KZN84590.1 - 0.012 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M24 PF00557.19 KZN84590.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 Metallopeptidase family M24 HI0933_like PF03486.9 KZN84590.1 - 0.052 12.0 0.4 0.091 11.2 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.1 KZN84590.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 KZN84590.1 - 0.084 13.2 1.1 0.26 11.7 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KZN84590.1 - 0.094 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KZN84591.1 - 1.2e-69 234.3 0.0 4.3e-69 232.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84591.1 - 8.4e-42 143.0 0.0 1.3e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KZN84591.1 - 7.8e-08 32.1 0.1 0.0041 17.0 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KZN84591.1 - 2e-07 30.2 0.0 4.4e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Cyto_ox_2 PF02322.10 KZN84592.1 - 0.71 8.9 18.6 0.18 10.9 3.6 2.3 2 1 0 2 2 2 0 Cytochrome oxidase subunit II AA_permease PF00324.16 KZN84593.1 - 7.8e-106 354.2 39.2 8.8e-106 354.0 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN84593.1 - 3.5e-29 101.6 43.8 9.2e-29 100.2 30.1 1.7 1 1 0 1 1 1 1 Amino acid permease OPA3 PF07047.7 KZN84596.1 - 7.7e-33 113.1 2.5 1.3e-32 112.4 1.7 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Mucin PF01456.12 KZN84596.1 - 0.77 9.5 10.2 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Integrin_beta PF00362.13 KZN84597.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Integrin, beta chain Myosin_head PF00063.16 KZN84598.1 - 6.8e-235 781.2 0.5 1e-234 780.7 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KZN84598.1 - 1.4e-50 171.4 0.0 2.4e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 KZN84598.1 - 1.6e-12 46.6 0.1 3.9e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN84598.1 - 5.6e-10 38.6 0.0 1.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KZN84598.1 - 7.3e-09 34.9 0.1 2.4e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 KZN84598.1 - 0.0041 16.6 7.9 0.48 10.2 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KZN84598.1 - 0.0073 16.4 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN84598.1 - 0.022 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 KZN84598.1 - 0.039 13.2 0.8 4.9 6.4 0.0 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 KZN84598.1 - 0.061 12.9 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KZN84598.1 - 0.092 13.5 0.0 0.27 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain P30 PF07390.6 KZN84599.1 - 0.03 13.8 4.8 0.06 12.8 3.3 1.4 1 0 0 1 1 1 0 Mycoplasma P30 protein p450 PF00067.17 KZN84600.1 - 7.8e-70 235.6 0.0 9.2e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.10 KZN84602.1 - 6.6e-294 975.1 0.2 8.2e-294 974.8 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KZN84602.1 - 1.9e-16 60.3 1.3 5.9e-16 58.7 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN84602.1 - 6.9e-13 48.9 0.0 1.3e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KZN84602.1 - 6.7e-09 35.4 0.1 6.8e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KZN84602.1 - 0.00015 21.4 0.0 0.007 16.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KZN84602.1 - 0.00087 18.6 0.1 0.0037 16.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Sel1 PF08238.7 KZN84603.1 - 1.9e-37 126.8 15.2 4.3e-06 27.1 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat Arrestin_C PF02752.17 KZN84604.1 - 1.3e-09 38.2 0.1 4.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KZN84604.1 - 3.9e-09 36.4 0.4 1.5e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Fungal_trans PF04082.13 KZN84605.1 - 6.2e-12 44.9 0.1 6.2e-12 44.9 0.1 2.3 2 2 1 3 3 3 1 Fungal specific transcription factor domain COesterase PF00135.23 KZN84606.1 - 2.2e-61 208.1 0.0 2.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN84606.1 - 4.4e-08 32.9 2.4 1.1e-06 28.4 1.7 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN84606.1 - 0.013 15.2 0.1 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KZN84607.1 - 1.1e-37 129.5 37.4 1.1e-37 129.5 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HpcH_HpaI PF03328.9 KZN84608.1 - 7e-31 106.8 0.0 8.8e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2-Hacid_dh_C PF02826.14 KZN84609.1 - 5.1e-48 162.5 0.0 6.7e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN84609.1 - 3.8e-23 81.4 0.0 4.4e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 KZN84609.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 KZN84609.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KZN84609.1 - 0.049 12.9 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KZN84609.1 - 0.056 13.1 0.2 0.2 11.4 0.1 1.7 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KZN84609.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KZN84610.1 - 0.00089 18.2 0.0 0.32 9.8 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain PARP PF00644.15 KZN84612.1 - 4.3e-62 209.1 0.0 1.2e-61 207.7 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KZN84612.1 - 8.8e-42 141.9 0.0 1.6e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KZN84612.1 - 7.8e-19 67.4 0.2 1.7e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KZN84612.1 - 2.2e-09 37.3 0.1 4.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KZN84612.1 - 1.6e-07 31.0 0.2 4.4e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 twin BRCT domain WD40 PF00400.27 KZN84613.1 - 3.7e-42 140.7 26.1 3.2e-11 42.6 0.1 11.6 11 0 0 11 11 11 8 WD domain, G-beta repeat NACHT PF05729.7 KZN84613.1 - 1.5e-14 54.0 0.0 3.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 KZN84613.1 - 1.9e-06 27.3 6.8 3.1 7.5 0.0 8.4 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 KZN84613.1 - 9.4e-05 21.9 4.5 0.3 10.4 0.1 3.6 2 2 0 2 2 2 2 PQQ-like domain AAA_16 PF13191.1 KZN84613.1 - 0.00011 22.1 0.0 0.0021 18.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Proteasome_A_N PF10584.4 KZN84613.1 - 0.00014 21.0 5.9 3.5 7.0 0.0 5.9 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature AAA PF00004.24 KZN84613.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1513 PF07433.6 KZN84613.1 - 0.0036 16.2 0.1 0.91 8.3 0.0 3.9 3 1 1 5 5 5 1 Protein of unknown function (DUF1513) AAA_19 PF13245.1 KZN84613.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain UPF0079 PF02367.12 KZN84613.1 - 0.032 13.8 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KZN84613.1 - 0.061 13.4 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KZN84613.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IKI3 PF04762.7 KZN84613.1 - 0.12 10.2 0.2 2.2 5.9 0.0 2.7 2 1 0 2 2 2 0 IKI3 family AAA_11 PF13086.1 KZN84613.1 - 0.12 11.8 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KZN84613.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain APH PF01636.18 KZN84614.1 - 1.6e-11 44.3 0.1 1.7e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN84614.1 - 0.00054 19.1 0.0 0.00062 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KZN84614.1 - 0.0018 17.8 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KZN84614.1 - 0.13 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase PfkB PF00294.19 KZN84617.1 - 1.1e-38 133.0 1.0 1.3e-38 132.8 0.7 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.13 KZN84618.1 - 0.0061 16.4 0.6 0.011 15.6 0.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.17 KZN84619.1 - 1.4e-05 24.8 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KZN84619.1 - 1 9.2 5.8 0.79 9.5 0.1 2.8 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain DUF3716 PF12511.3 KZN84620.1 - 1.3e-16 59.9 1.4 2e-16 59.3 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3716 PF12511.3 KZN84621.1 - 5e-17 61.2 3.1 8e-17 60.6 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HNH_2 PF13391.1 KZN84623.1 - 0.00032 20.4 0.1 0.00047 19.8 0.1 1.2 1 0 0 1 1 1 1 HNH endonuclease Sugar_tr PF00083.19 KZN84625.1 - 9.2e-106 354.1 31.1 5.3e-105 351.5 21.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84625.1 - 1.3e-21 76.7 59.6 2e-14 53.0 17.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN84625.1 - 0.31 9.3 42.3 0.0093 14.4 6.6 3.5 2 2 1 3 3 3 0 MFS/sugar transport protein Fungal_trans_2 PF11951.3 KZN84626.1 - 5e-10 38.5 0.0 1.2e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain nlz1 PF12402.3 KZN84627.1 - 0.12 12.7 0.8 0.26 11.6 0.4 1.6 1 1 1 2 2 2 0 NocA-like zinc-finger protein 1 NmrA PF05368.8 KZN84628.1 - 3.5e-14 52.6 0.0 1.1e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KZN84628.1 - 0.0004 20.4 0.2 0.00079 19.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN84628.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN84629.1 - 9.5e-34 116.4 0.0 1.3e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KZN84629.1 - 8e-08 31.9 0.0 2.8e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KZN84629.1 - 0.067 13.0 0.0 0.27 11.1 0.0 2.1 1 1 0 1 1 1 0 short chain dehydrogenase ketoacyl-synt PF00109.21 KZN84630.1 - 5.6e-67 225.8 0.0 1.5e-66 224.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN84630.1 - 6e-66 222.9 0.0 2.7e-65 220.7 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KZN84630.1 - 1.3e-57 194.4 0.2 2.5e-57 193.4 0.1 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KZN84630.1 - 3.4e-54 184.0 0.0 5.4e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KZN84630.1 - 1e-44 152.3 1.5 2.8e-44 150.9 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN84630.1 - 1.4e-27 95.9 0.4 3e-27 94.8 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KZN84630.1 - 2.1e-17 63.3 0.0 5.7e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84630.1 - 3.4e-13 49.6 0.0 7.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN84630.1 - 3.5e-12 47.3 0.0 1.3e-11 45.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN84630.1 - 1.8e-10 40.4 0.1 1.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KZN84630.1 - 8.4e-09 35.1 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN84630.1 - 1.4e-08 35.0 0.0 3.9e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN84630.1 - 3.1e-08 34.1 0.0 8.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KZN84630.1 - 8.2e-07 28.7 0.4 8.2e-07 28.7 0.3 2.3 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KZN84630.1 - 3.4e-05 24.0 0.0 0.00015 21.9 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KZN84630.1 - 0.00018 20.6 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KZN84630.1 - 0.00078 19.4 0.0 0.0026 17.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84630.1 - 0.0014 19.0 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KZN84630.1 - 0.0014 18.0 0.0 0.0039 16.6 0.0 1.7 2 0 0 2 2 1 1 Putative methyltransferase Thiolase_N PF00108.18 KZN84630.1 - 0.0045 16.0 0.3 0.0087 15.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF938 PF06080.7 KZN84630.1 - 0.015 14.8 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF938) 3Beta_HSD PF01073.14 KZN84630.1 - 0.025 13.3 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.5 KZN84630.1 - 0.069 12.8 0.4 0.19 11.4 0.3 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.7 KZN84630.1 - 0.56 9.0 0.0 1.1 8.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Acetyltransf_2 PF00797.12 KZN84632.1 - 1.7e-27 96.5 0.0 2.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase GDPD PF03009.12 KZN84633.1 - 2.3e-13 50.2 0.0 4.5e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Zip PF02535.17 KZN84635.1 - 3.9e-51 173.9 0.3 4.6e-51 173.7 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 KZN84635.1 - 0.085 12.0 1.7 0.21 10.7 1.2 1.6 1 0 0 1 1 1 0 UNC-50 family bZIP_1 PF00170.16 KZN84636.1 - 3.7e-05 23.6 28.0 3.8e-05 23.5 9.6 3.3 1 1 2 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 KZN84636.1 - 0.0077 16.0 26.7 0.016 14.9 8.9 3.4 2 1 1 3 3 3 3 Basic region leucine zipper bZIP_Maf PF03131.12 KZN84636.1 - 0.43 10.9 18.3 0.12 12.6 6.5 2.9 1 1 1 2 2 2 0 bZIP Maf transcription factor APG6 PF04111.7 KZN84636.1 - 6.1 5.7 15.5 10 5.0 10.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-CCCH PF00642.19 KZN84637.1 - 3.4e-16 58.4 30.3 1.9e-05 24.2 0.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KZN84637.1 - 0.067 12.6 2.6 0.29 10.6 0.1 2.9 2 0 0 2 2 2 0 Putative zinc-finger domain Ebp2 PF05890.7 KZN84637.1 - 0.25 10.5 4.8 0.54 9.5 3.3 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 LRV_FeS PF05484.6 KZN84637.1 - 1.6 8.3 6.9 3.1 7.4 0.3 3.4 2 1 1 3 3 3 0 LRV protein FeS4 cluster TFIIF_beta PF02270.10 KZN84638.1 - 1.3e-82 277.6 0.4 1.6e-82 277.4 0.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF859 PF05895.7 KZN84638.1 - 0.017 13.3 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) PCI PF01399.22 KZN84640.1 - 1.5e-12 47.7 0.0 4.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KZN84640.1 - 6.7e-05 22.3 0.3 0.00011 21.6 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KZN84640.1 - 0.00029 21.1 1.4 0.0047 17.2 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat PspA_IM30 PF04012.7 KZN84640.1 - 0.0095 15.3 1.6 0.021 14.1 1.1 1.5 1 0 0 1 1 1 1 PspA/IM30 family TPR_14 PF13428.1 KZN84640.1 - 0.022 15.3 3.7 17 6.3 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Herpes_UL14 PF03580.9 KZN84640.1 - 0.044 13.5 2.2 0.65 9.7 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus UL14-like protein TPR_12 PF13424.1 KZN84640.1 - 0.17 11.8 3.4 0.76 9.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldedh PF00171.17 KZN84642.1 - 9.1e-130 433.0 1.0 6.3e-75 252.2 0.6 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_2 PF00890.19 KZN84643.1 - 3.3e-85 286.4 0.8 4.2e-85 286.1 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KZN84643.1 - 1.6e-18 66.2 3.1 1.7e-18 66.1 0.0 2.6 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KZN84643.1 - 2.5e-12 46.3 2.3 2e-11 43.4 1.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN84643.1 - 4.4e-10 39.7 0.0 3.4e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN84643.1 - 5.2e-09 36.0 0.6 5.4e-08 32.7 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN84643.1 - 7.5e-08 31.2 0.8 0.0022 16.5 0.0 3.1 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.2 KZN84643.1 - 9.6e-08 31.5 0.5 2.7e-07 30.0 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN84643.1 - 1.7e-06 27.3 0.4 0.0011 18.1 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 KZN84643.1 - 4.2e-05 22.7 0.1 7.4e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN84643.1 - 0.0005 20.1 0.5 0.003 17.6 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN84643.1 - 0.00091 18.1 3.2 0.1 11.4 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KZN84643.1 - 0.0015 17.6 0.1 0.92 8.5 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Ribosomal_60s PF00428.14 KZN84643.1 - 0.027 14.8 3.0 0.065 13.6 2.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pyr_redox PF00070.22 KZN84643.1 - 0.078 13.3 1.4 3.9 7.9 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Histone_HNS PF00816.16 KZN84644.1 - 0.00015 22.2 0.1 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 H-NS histone family WD40 PF00400.27 KZN84645.1 - 1.9e-12 46.5 3.2 0.22 11.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Serglycin PF04360.7 KZN84645.1 - 0.1 12.2 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Serglycin PAH PF02671.16 KZN84646.1 - 2.1e-41 139.2 1.1 4.7e-16 58.1 0.4 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KZN84646.1 - 1.9e-40 136.6 0.0 4.7e-40 135.4 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.10 KZN84647.1 - 1.8e-49 168.1 0.0 2.8e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KZN84647.1 - 1.8e-37 128.3 0.0 3e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_17 PF00332.13 KZN84649.1 - 0.015 14.3 0.8 0.05 12.6 0.2 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 FAM176 PF14851.1 KZN84650.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM176 family CcoS PF03597.10 KZN84650.1 - 1.6 8.2 9.5 3.9 6.9 6.6 1.6 1 1 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Orbi_VP6 PF01516.11 KZN84650.1 - 2.7 6.9 6.9 7.8 5.4 0.0 2.0 2 0 0 2 2 2 0 Orbivirus helicase VP6 DUF808 PF05661.7 KZN84651.1 - 0.074 11.8 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) HemY_N PF07219.8 KZN84651.1 - 0.56 9.7 2.9 1.7 8.2 2.0 1.8 1 1 0 1 1 1 0 HemY protein N-terminus MFS_1 PF07690.11 KZN84652.1 - 1.8e-30 105.8 35.8 1.8e-30 105.8 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.19 KZN84652.1 - 0.013 14.9 11.8 0.038 13.4 1.3 2.9 2 1 0 2 2 2 0 Fatty acid desaturase MFS_1 PF07690.11 KZN84653.1 - 7.3e-23 80.8 44.6 2.2e-15 56.2 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN84653.1 - 0.0023 16.2 6.9 0.0025 16.0 4.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_Fe-S_N PF10399.4 KZN84653.1 - 0.31 10.2 4.6 12 5.1 0.0 3.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sugar_tr PF00083.19 KZN84654.1 - 1.1e-71 241.8 24.2 1.3e-71 241.5 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84654.1 - 2.6e-19 69.1 43.2 4.5e-14 51.9 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN84654.1 - 0.0022 16.3 17.0 0.008 14.4 1.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Transgly_assoc PF04226.8 KZN84654.1 - 0.54 10.3 7.4 0.56 10.3 0.1 4.2 4 0 0 4 4 4 0 Transglycosylase associated protein SdpI PF13630.1 KZN84654.1 - 7.9 6.2 18.0 8.8 6.1 0.4 4.1 3 0 0 3 3 3 0 SdpI/YhfL protein family Sel1 PF08238.7 KZN84655.1 - 2.8e-21 75.4 7.9 1.6e-07 31.7 0.4 3.7 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 KZN84655.1 - 0.0031 17.8 2.7 0.54 10.8 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84655.1 - 0.059 14.0 3.6 0.57 10.9 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 KZN84656.1 - 3.1e-51 173.0 9.2 4.2e-51 172.6 6.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2526 PF10735.4 KZN84656.1 - 0.017 15.0 2.3 0.092 12.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) DUF445 PF04286.7 KZN84656.1 - 0.037 13.5 6.3 0.053 13.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) GSH_synth_ATP PF03917.12 KZN84656.1 - 0.085 11.4 5.2 0.15 10.6 3.6 1.4 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain CBF PF03914.12 KZN84657.1 - 6.4e-48 162.3 0.3 1.4e-47 161.2 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family MIF4G PF02854.14 KZN84657.1 - 0.0019 17.6 0.3 1.5 8.2 0.0 2.6 2 0 0 2 2 2 2 MIF4G domain LemA PF04011.7 KZN84657.1 - 0.002 17.2 0.2 0.0066 15.5 0.1 1.8 1 0 0 1 1 1 1 LemA family GPI-anchored PF10342.4 KZN84658.1 - 1.2e-17 64.2 0.7 1.2e-17 64.2 0.5 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4449 PF14613.1 KZN84658.1 - 0.13 12.1 0.4 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Macoilin PF09726.4 KZN84658.1 - 1.5 7.0 7.1 1.7 6.8 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KZN84659.1 - 0.0091 15.9 16.1 0.0091 15.9 11.2 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.11 KZN84659.1 - 0.8 9.1 7.5 0.66 9.4 0.0 3.7 3 1 1 4 4 4 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 KZN84659.1 - 3.1 6.9 5.5 2.6 7.1 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DXP_reductoisom PF02670.11 KZN84659.1 - 3.7 8.0 8.1 5.3 7.5 0.3 2.6 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase APG6 PF04111.7 KZN84659.1 - 4.7 6.1 39.4 0.94 8.4 18.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Hydrolase_like PF13242.1 KZN84661.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like MMS19_C PF12460.3 KZN84663.1 - 2.1e-127 425.3 18.4 2.4e-127 425.1 7.1 3.2 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 KZN84663.1 - 1.3e-94 316.3 0.1 2.2e-93 312.2 0.0 2.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 KZN84663.1 - 1.4e-07 31.6 13.8 0.065 13.5 0.3 7.0 7 2 0 7 7 7 3 HEAT repeats Arm PF00514.18 KZN84663.1 - 0.0022 17.7 0.8 1.5 8.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KZN84663.1 - 0.0028 17.5 13.5 28 5.1 0.2 7.4 7 0 0 7 7 7 0 HEAT repeat DUF2435 PF10363.4 KZN84663.1 - 0.0068 16.2 5.2 3.8 7.4 0.0 4.4 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KZN84663.1 - 2.7 8.5 22.5 24 5.5 1.6 6.8 6 1 0 6 6 6 0 HEAT-like repeat Fasciclin PF02469.17 KZN84664.1 - 2.2e-08 34.1 0.0 3.9e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 KZN84665.1 - 3.4e-47 160.1 0.9 4.3e-47 159.7 0.6 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 KZN84666.1 - 8e-45 152.3 0.0 9.1e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MFS_2 PF13347.1 KZN84666.1 - 0.014 13.8 0.8 0.018 13.4 0.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Ion_trans_N PF08412.5 KZN84667.1 - 0.69 9.2 5.1 16 4.9 1.8 2.2 2 0 0 2 2 2 0 Ion transport protein N-terminal THF_DHG_CYH PF00763.18 KZN84668.1 - 8.4e-20 70.9 0.2 1.3e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KZN84668.1 - 9.4e-12 44.2 0.1 1.1e-09 37.5 0.0 2.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 KZN84669.1 - 4.5e-71 238.7 0.0 6.3e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KZN84669.1 - 1e-25 90.3 0.1 3e-25 88.8 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KZN84669.1 - 1.1e-15 57.5 2.7 2.7e-15 56.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KZN84669.1 - 0.0071 16.2 1.0 0.029 14.2 0.7 2.0 1 1 1 2 2 2 1 HAS barrel domain DUF962 PF06127.6 KZN84670.1 - 1.4e-17 63.3 2.6 2.1e-17 62.8 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.12 KZN84671.1 - 7.6e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KZN84671.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Piwi PF02171.12 KZN84673.1 - 3.7e-72 242.8 0.0 5.8e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KZN84673.1 - 1.5e-12 46.9 0.0 3.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KZN84673.1 - 1e-11 44.0 0.2 2.5e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) E1-E2_ATPase PF00122.15 KZN84674.1 - 7.2e-56 188.7 0.0 1.7e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN84674.1 - 8.5e-48 162.2 11.5 8.5e-48 162.2 8.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN84674.1 - 4.5e-23 82.7 0.0 7.8e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN84674.1 - 9.5e-20 70.3 0.0 1.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KZN84674.1 - 7.5e-12 44.5 0.5 1.6e-10 40.3 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KZN84674.1 - 1.3e-11 45.0 0.0 3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN84674.1 - 0.00019 21.0 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KZN84674.1 - 0.015 15.2 0.0 0.015 15.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3325) Chitin_bind_1 PF00187.14 KZN84675.1 - 4.2e-05 23.4 5.9 4.2e-05 23.4 4.1 3.2 2 1 1 3 3 3 1 Chitin recognition protein LysM PF01476.15 KZN84675.1 - 0.00018 21.3 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 LysM domain Dicty_REP PF05086.7 KZN84675.1 - 1.7 6.2 6.9 2.3 5.8 4.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Paramyxo_C PF01692.13 KZN84675.1 - 8.7 5.8 13.7 13 5.2 9.5 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c HSP20 PF00011.16 KZN84676.1 - 1.1e-18 67.0 0.0 1.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family dCMP_cyt_deam_1 PF00383.17 KZN84677.1 - 1.1e-14 53.8 0.1 1.5e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KZN84677.1 - 0.0002 21.0 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain UBN2_3 PF14244.1 KZN84678.1 - 0.00057 19.4 0.1 0.042 13.4 0.0 2.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type CST-I PF06002.7 KZN84678.1 - 0.021 14.0 0.2 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) CagZ PF09053.5 KZN84678.1 - 0.085 12.1 1.5 0.71 9.1 0.5 2.2 1 1 1 2 2 2 0 CagZ MSP7_C PF12948.2 KZN84678.1 - 0.47 10.7 3.6 0.94 9.7 0.1 2.7 2 2 1 3 3 3 0 MSP7-like protein C-terminal domain NAD_binding_8 PF13450.1 KZN84680.1 - 1.2e-10 41.2 0.0 2.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN84680.1 - 8e-08 32.5 0.0 1.4e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN84680.1 - 2.5e-06 26.7 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KZN84680.1 - 6.2e-06 25.3 0.2 1.9e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KZN84680.1 - 4.7e-05 22.5 0.0 8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KZN84680.1 - 7.3e-05 22.7 0.1 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN84680.1 - 0.00013 20.5 0.1 0.00022 19.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KZN84680.1 - 0.00072 18.5 0.0 0.0051 15.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KZN84680.1 - 0.0015 17.7 0.0 0.0058 15.7 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KZN84680.1 - 0.003 16.6 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KZN84680.1 - 0.012 14.4 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN84680.1 - 0.15 11.8 0.3 1 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4541 PF15074.1 KZN84680.1 - 0.16 12.5 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) FA_desaturase PF00487.19 KZN84681.1 - 4.9e-25 88.4 19.2 7.9e-25 87.7 13.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KZN84681.1 - 0.00045 20.2 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) MFS_1 PF07690.11 KZN84682.1 - 1.2e-38 132.7 46.9 1.2e-38 132.7 32.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN84682.1 - 1.9e-19 69.3 29.8 3.2e-19 68.5 20.7 1.2 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN84682.1 - 1.2e-14 53.7 18.1 1.2e-14 53.7 12.5 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter DUF4448 PF14610.1 KZN84682.1 - 1.1 8.6 3.8 19 4.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) Abhydrolase_3 PF07859.8 KZN84683.1 - 5.4e-38 130.6 0.0 7.6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN84683.1 - 1.5e-05 23.9 0.1 0.00015 20.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KZN84683.1 - 4.8e-05 23.1 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN84683.1 - 0.00077 18.7 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KZN84683.1 - 0.0026 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KZN84683.1 - 0.0064 15.0 0.0 0.0091 14.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KZN84683.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family 4HBT_3 PF13622.1 KZN84683.1 - 0.11 12.2 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily PMP1_2 PF08114.6 KZN84685.1 - 0.096 12.1 0.1 0.096 12.1 0.1 2.7 3 0 0 3 3 3 0 ATPase proteolipid family COesterase PF00135.23 KZN84686.1 - 5.6e-68 229.9 0.1 7e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN84686.1 - 4.2e-06 26.4 1.6 5.4e-06 26.1 0.2 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KZN84686.1 - 0.0054 16.0 0.5 0.13 11.4 0.1 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KZN84686.1 - 0.0055 16.6 0.2 0.011 15.6 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN84686.1 - 0.0097 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN84686.1 - 0.031 14.0 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GATase PF00117.23 KZN84687.1 - 1.6e-08 34.2 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN84687.1 - 0.027 13.9 0.0 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 OPT PF03169.10 KZN84688.1 - 1.8e-128 429.6 40.5 2.1e-128 429.4 28.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sial-lect-inser PF09264.5 KZN84688.1 - 0.0022 17.3 0.1 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae sialidase, lectin insertion DUF2370 PF10176.4 KZN84688.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3661 PF12400.3 KZN84688.1 - 0.089 12.8 4.8 0.073 13.1 0.7 2.4 2 0 0 2 2 2 0 Vaculolar membrane protein DUF2207 PF09972.4 KZN84688.1 - 0.3 9.6 2.8 0.17 10.4 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3425 PF11905.3 KZN84689.1 - 3.6e-36 124.0 1.6 5.7e-36 123.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KZN84689.1 - 0.24 11.3 4.6 0.4 10.6 3.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.20 KZN84690.1 - 3.5e-20 72.5 0.0 5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84690.1 - 0.00023 20.8 1.1 0.0059 16.2 0.3 2.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN84690.1 - 0.0062 16.0 0.1 0.034 13.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN84690.1 - 0.049 12.3 0.1 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_5 PF12695.2 KZN84691.1 - 5.3e-14 52.1 0.0 8.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN84691.1 - 1.2e-13 51.4 0.0 1.9e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN84691.1 - 3.8e-06 26.3 0.0 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.6 KZN84691.1 - 0.00036 19.2 0.0 0.00048 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 KZN84691.1 - 0.00058 19.3 0.1 0.00082 18.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KZN84691.1 - 0.0031 16.0 0.1 0.082 11.3 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) FTCD_C PF04961.7 KZN84691.1 - 0.015 14.7 0.2 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase HET PF06985.6 KZN84692.1 - 1.4e-06 28.5 0.0 0.00018 21.6 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 KZN84693.1 - 1.7e-79 266.8 0.0 2.5e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN84693.1 - 5.1e-51 173.3 0.0 1.2e-50 172.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN84693.1 - 2.4e-22 78.6 0.0 5e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Isochorismatase PF00857.15 KZN84694.1 - 8.9e-41 139.7 0.2 1e-40 139.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Catalase PF00199.14 KZN84695.1 - 1.5e-109 366.2 5.8 7.1e-60 202.7 0.4 3.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 KZN84695.1 - 5e-09 35.8 0.0 2.1e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive ASD2 PF08687.6 KZN84695.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GMC_oxred_C PF05199.8 KZN84696.1 - 0.00078 19.7 0.0 0.0009 19.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KZN84697.1 - 8.1e-16 58.5 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN84697.1 - 1.9e-08 33.6 0.1 0.00043 19.2 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN84697.1 - 3.7e-07 28.9 0.0 5.8e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KZN84697.1 - 1.1e-06 28.9 0.1 0.018 15.1 0.0 2.9 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN84697.1 - 0.00014 20.8 0.0 0.00055 18.9 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KZN84697.1 - 0.00014 20.8 0.1 0.0014 17.6 0.0 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN84697.1 - 0.00017 21.3 0.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN84697.1 - 0.00026 20.9 0.1 0.00064 19.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN84697.1 - 0.00082 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KZN84697.1 - 0.0011 17.9 0.1 0.039 12.8 0.0 2.3 1 1 1 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KZN84697.1 - 0.004 16.2 0.1 0.0066 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 KZN84697.1 - 0.0094 14.9 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KZN84697.1 - 0.024 13.7 1.8 0.025 13.6 0.1 1.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN84697.1 - 0.029 14.7 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN84697.1 - 0.032 12.8 0.0 0.054 12.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase CpeS PF09367.5 KZN84698.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 CpeS-like protein Pro-NT_NN PF07421.6 KZN84698.1 - 0.07 12.6 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor DUF2229 PF09989.4 KZN84698.1 - 0.075 12.4 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) APH PF01636.18 KZN84699.1 - 4.8e-12 46.1 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KZN84699.1 - 0.00026 20.2 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KZN84699.1 - 0.0055 16.2 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN84699.1 - 0.03 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.17 KZN84699.1 - 0.12 11.6 0.0 0.58 9.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KZN84700.1 - 2.8e-14 53.4 0.0 7e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN84700.1 - 0.00084 18.0 0.0 0.93 8.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GXWXG PF14231.1 KZN84702.1 - 0.00023 20.7 0.0 95 2.7 0.0 5.5 6 0 0 6 6 6 4 GXWXG protein G-alpha PF00503.15 KZN84705.1 - 4.2e-54 183.7 6.9 4e-40 137.7 1.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KZN84705.1 - 4.9e-11 42.1 0.1 1.1e-10 41.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN84705.1 - 1.5e-06 27.5 0.2 1.8e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN84705.1 - 1.5e-05 25.4 0.0 3.8e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KZN84705.1 - 0.002 17.6 0.1 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KZN84705.1 - 0.0061 15.7 0.0 0.013 14.7 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KZN84705.1 - 0.014 15.2 0.0 0.044 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KZN84705.1 - 0.019 13.8 0.3 0.032 13.0 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KZN84705.1 - 0.02 15.1 0.5 0.035 14.4 0.3 1.5 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KZN84705.1 - 0.025 14.0 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KZN84705.1 - 0.031 14.2 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.8 KZN84705.1 - 0.04 12.8 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KZN84705.1 - 0.046 14.5 0.6 0.1 13.3 0.4 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KZN84705.1 - 0.056 12.4 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 KZN84705.1 - 0.085 12.2 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KZN84705.1 - 0.11 11.9 0.3 7.3 6.0 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 KZN84705.1 - 0.11 11.3 0.4 0.19 10.5 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 KZN84705.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NYN PF01936.13 KZN84706.1 - 9.7e-32 110.2 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 KZN84706.1 - 1.7e-14 53.3 0.0 3.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Fe-S_assembly PF04384.8 KZN84706.1 - 0.0031 17.8 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Frag1 PF10277.4 KZN84707.1 - 0.0095 15.4 1.8 0.056 12.9 0.1 2.1 1 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family DUF914 PF06027.7 KZN84707.1 - 0.016 14.0 0.1 0.033 13.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF975 PF06161.6 KZN84707.1 - 0.048 13.4 0.6 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF975) Vps54 PF07928.7 KZN84707.1 - 0.065 13.3 1.5 0.78 9.8 0.1 2.5 2 1 0 2 2 2 0 Vps54-like protein Cyto_ox_2 PF02322.10 KZN84707.1 - 0.33 10.0 3.6 0.41 9.7 0.4 2.0 2 0 0 2 2 2 0 Cytochrome oxidase subunit II BIR PF00653.16 KZN84708.1 - 6.5e-05 23.2 0.1 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain TPR_10 PF13374.1 KZN84709.1 - 4.5e-85 277.4 7.6 2.1e-12 46.5 0.0 8.0 7 1 1 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KZN84709.1 - 3.9e-69 228.5 10.0 7.7e-16 57.7 0.0 5.2 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KZN84709.1 - 1e-26 90.5 13.9 0.0011 18.6 0.1 8.2 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_4 PF07721.9 KZN84709.1 - 4.8e-23 79.1 1.2 0.025 14.9 0.0 6.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KZN84709.1 - 7.6e-22 75.6 11.4 0.03 14.5 0.0 8.1 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84709.1 - 2.4e-20 71.1 7.7 0.071 12.7 0.0 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 KZN84709.1 - 6.5e-20 69.4 7.0 0.21 11.5 0.0 8.0 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KZN84709.1 - 9.5e-18 63.6 4.9 0.0011 18.5 0.1 6.4 1 1 5 6 6 6 5 TPR repeat TPR_19 PF14559.1 KZN84709.1 - 2e-14 53.6 8.6 0.075 13.3 0.0 7.3 3 1 4 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84709.1 - 2.6e-14 53.4 3.7 0.013 16.2 0.1 6.6 4 1 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84709.1 - 1.9e-12 46.6 8.6 4.3 8.2 0.1 7.7 5 2 2 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84709.1 - 7.2e-09 34.7 6.3 1.6 8.6 0.1 7.1 7 1 1 8 8 7 1 Tetratricopeptide repeat PPR PF01535.15 KZN84709.1 - 6.9e-08 31.9 0.3 15 5.7 0.0 7.1 6 1 1 7 7 7 0 PPR repeat Apc3 PF12895.2 KZN84709.1 - 4.2e-07 30.0 0.6 0.22 11.6 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 KZN84709.1 - 1e-06 28.5 2.3 1.7 9.1 0.0 6.4 7 0 0 7 7 6 1 Pentatricopeptide repeat domain TPR_20 PF14561.1 KZN84709.1 - 2.4e-06 27.5 8.5 7.3 6.7 0.0 6.5 1 1 5 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 KZN84709.1 - 1.1e-05 25.0 0.0 9.9 6.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN84709.1 - 4.1e-05 23.7 12.3 29 5.4 0.0 8.1 8 1 1 9 9 7 0 Tetratricopeptide repeat DUF4074 PF13293.1 KZN84709.1 - 4.1e-05 23.7 2.4 33 4.8 0.0 6.3 7 1 1 8 8 6 0 Domain of unknown function (DUF4074) SLT_2 PF13406.1 KZN84709.1 - 4.5e-05 22.4 1.3 0.11 11.3 0.2 3.9 1 1 1 3 3 3 1 Transglycosylase SLT domain Rab5-bind PF09311.6 KZN84709.1 - 9.4e-05 22.3 7.6 1.3 8.8 1.1 4.8 1 1 3 4 4 4 1 Rabaptin-like protein DUF3157 PF11355.3 KZN84709.1 - 0.00016 21.0 1.9 0.53 9.5 0.1 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF3157) SNAP PF14938.1 KZN84709.1 - 0.0039 16.3 0.5 0.056 12.5 0.2 2.2 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP DUF4054 PF13262.1 KZN84709.1 - 0.0051 17.0 1.5 1.4 9.1 0.0 3.5 4 0 0 4 4 3 1 Protein of unknown function (DUF4054) DUF367 PF04034.8 KZN84709.1 - 0.015 14.8 0.2 8.4 6.0 0.0 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF367) DNAJ_related PF12339.3 KZN84709.1 - 0.041 13.7 2.5 2.4 8.0 0.1 3.0 1 1 2 4 4 4 0 DNA-J related protein DUF3662 PF12401.3 KZN84709.1 - 0.041 14.0 1.5 28 4.9 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2662) PPR_1 PF12854.2 KZN84709.1 - 0.066 12.6 2.8 41 3.7 0.0 4.8 5 0 0 5 5 5 0 PPR repeat TPM PF04536.9 KZN84709.1 - 0.092 12.6 0.6 17 5.3 0.0 3.4 4 0 0 4 4 4 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase PNPase PF03726.9 KZN84709.1 - 0.095 12.9 0.5 21 5.4 0.0 3.8 3 2 2 5 5 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3268 PF11672.3 KZN84709.1 - 0.11 12.5 0.0 27 4.9 0.0 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3268) DUF3366 PF11846.3 KZN84709.1 - 0.11 12.3 4.0 34 4.2 0.0 4.3 1 1 4 5 5 5 0 Domain of unknown function (DUF3366) SASP PF00269.15 KZN84709.1 - 0.12 12.2 4.4 1.7 8.5 0.2 3.8 3 1 1 4 4 3 0 Small, acid-soluble spore proteins, alpha/beta type DUF1897 PF09005.5 KZN84709.1 - 0.14 11.6 6.8 15 5.0 0.1 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1897) Dimer_Tnp_Tn5 PF02281.11 KZN84709.1 - 0.16 12.0 2.5 29 4.8 0.0 3.6 2 2 0 4 4 3 0 Transposase Tn5 dimerisation domain COesterase PF00135.23 KZN84710.1 - 1.6e-83 281.2 0.6 2.1e-83 280.8 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN84710.1 - 2.3e-07 30.5 0.1 3e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN84710.1 - 0.037 12.6 0.0 0.17 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) PLAC8 PF04749.12 KZN84711.1 - 7.8e-26 90.7 9.7 9.8e-26 90.3 6.7 1.1 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.27 KZN84712.1 - 2e-144 464.9 27.4 1.2e-14 53.5 0.2 13.3 13 0 0 13 13 13 11 WD domain, G-beta repeat IKI3 PF04762.7 KZN84712.1 - 1.9e-10 39.2 1.5 0.00071 17.5 0.1 4.0 2 1 1 4 4 4 2 IKI3 family NACHT PF05729.7 KZN84712.1 - 3.5e-10 39.7 0.5 1.2e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain eIF2A PF08662.6 KZN84712.1 - 1.8e-08 34.3 0.0 0.16 11.6 0.0 4.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KZN84712.1 - 3.2e-08 32.7 10.5 3.4 7.0 0.0 8.1 8 0 0 8 8 8 3 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 KZN84712.1 - 4.3e-07 28.5 0.5 0.0012 17.2 0.0 4.4 1 1 5 6 6 6 1 Cytochrome D1 heme domain PD40 PF07676.7 KZN84712.1 - 4.8e-07 29.2 7.5 22 4.8 0.0 9.0 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 KZN84712.1 - 1.6e-06 28.2 3.2 3e-06 27.3 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain DUF1258 PF06869.7 KZN84712.1 - 6.2e-06 25.4 0.2 1.7 7.6 0.0 6.4 2 1 6 8 8 8 1 Protein of unknown function (DUF1258) DUF642 PF04862.7 KZN84712.1 - 1.6e-05 24.6 0.0 7.5 6.1 0.0 5.0 3 1 2 6 6 6 0 Protein of unknown function (DUF642) TruB_C PF09142.6 KZN84712.1 - 2.7e-05 23.7 1.4 78 3.0 0.0 7.4 9 0 0 9 9 7 0 tRNA Pseudouridine synthase II, C terminal AAA_22 PF13401.1 KZN84712.1 - 0.0017 18.5 0.1 0.013 15.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KZN84712.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KZN84712.1 - 0.017 13.9 0.0 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Nucleoporin_N PF08801.6 KZN84712.1 - 0.034 12.8 3.2 11 4.6 0.2 4.2 1 1 3 4 4 4 0 Nup133 N terminal like AAA PF00004.24 KZN84712.1 - 0.035 14.2 0.7 0.27 11.4 0.0 2.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN84712.1 - 0.038 14.8 0.0 0.2 12.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 KZN84712.1 - 0.068 12.1 3.3 1.9 7.4 1.2 2.6 2 1 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.15 KZN84712.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PIF1 PF05970.9 KZN84712.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Mito_carr PF00153.22 KZN84714.1 - 3e-67 222.3 1.6 3.2e-22 78.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.10 KZN84714.1 - 0.018 14.6 0.6 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 Chromate transporter Glyco_hydro_42 PF02449.10 KZN84714.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Abi PF02517.11 KZN84715.1 - 2.4e-12 46.8 11.3 2.4e-12 46.8 7.8 2.6 1 1 1 2 2 2 1 CAAX protease self-immunity Synaptobrevin PF00957.16 KZN84716.1 - 0.031 13.8 2.1 0.057 13.0 1.4 1.3 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.14 KZN84717.1 - 2.1e-48 165.1 7.7 3.4e-48 164.4 5.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 KZN84718.1 - 6.3e-150 500.4 0.0 7.2e-150 500.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 KZN84718.1 - 0.048 13.0 0.0 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.20 KZN84719.1 - 9.9e-23 80.8 0.0 1.4e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84719.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN84719.1 - 1.7e-06 27.6 0.0 2.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN84719.1 - 0.00083 19.4 0.1 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KZN84719.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN84719.1 - 0.0012 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KZN84719.1 - 0.0019 17.4 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KZN84719.1 - 0.0037 16.0 0.0 0.0054 15.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KZN84719.1 - 0.0073 16.2 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KZN84719.1 - 0.061 12.2 0.0 4 6.2 0.0 2.5 2 1 1 3 3 3 0 Male sterility protein HNH_2 PF13391.1 KZN84720.1 - 1.4e-06 27.9 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease CENP-F_leu_zip PF10473.4 KZN84720.1 - 0.13 12.1 2.6 0.22 11.3 1.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.1 KZN84720.1 - 0.33 9.8 8.1 0.088 11.7 3.6 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF3318 PF11780.3 KZN84721.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) FMO-like PF00743.14 KZN84722.1 - 3.6e-24 84.8 0.1 1e-16 60.2 0.0 3.0 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN84722.1 - 1.8e-23 83.6 0.0 4e-23 82.5 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN84722.1 - 2.2e-11 43.9 0.0 6.2e-10 39.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN84722.1 - 2.3e-09 37.5 0.2 0.0025 18.1 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN84722.1 - 5.3e-09 35.5 0.2 0.0014 17.7 0.1 3.2 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 KZN84722.1 - 5.5e-08 32.1 0.2 2.6e-06 26.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN84722.1 - 1.1e-06 28.4 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN84722.1 - 3.6e-05 22.9 0.0 0.12 11.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KZN84722.1 - 4.2e-05 22.6 0.4 0.058 12.2 0.2 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KZN84722.1 - 4.5e-05 22.6 0.0 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KZN84722.1 - 8e-05 21.8 0.0 0.065 12.2 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KZN84722.1 - 0.0012 17.7 0.3 0.17 10.7 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN84722.1 - 0.0036 17.0 4.3 3.5 7.3 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KZN84722.1 - 0.0047 15.4 0.1 0.54 8.6 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN84722.1 - 0.081 11.7 0.1 1.2 7.9 0.1 2.5 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KZN84722.1 - 0.084 11.7 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 KZN84722.1 - 0.092 12.8 0.0 22 5.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KZN84723.1 - 8.3e-19 68.2 0.0 2.7e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN84723.1 - 1.8e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KZN84723.1 - 0.0073 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KZN84723.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KZN84723.1 - 0.041 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 KZN84724.1 - 3.4e-112 375.2 24.4 4.1e-112 375.0 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84724.1 - 4.7e-24 84.7 64.9 2.9e-18 65.7 26.0 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN84724.1 - 2.2e-07 29.4 14.1 3.6e-05 22.1 4.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 KZN84724.1 - 0.0019 17.6 2.4 0.0019 17.6 1.6 3.4 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 tRNA-synt_1 PF00133.17 KZN84725.1 - 1.4e-55 188.4 0.0 2.9e-34 118.0 0.1 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KZN84725.1 - 9.4e-39 132.6 0.0 1.4e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KZN84725.1 - 1.3e-28 99.7 0.0 5.1e-22 78.0 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KZN84725.1 - 9e-11 41.7 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 KZN84725.1 - 0.00025 19.9 0.0 0.00046 19.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Suc_Fer-like PF06999.7 KZN84726.1 - 6.6e-46 157.1 0.0 9e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like 2-Hacid_dh_C PF02826.14 KZN84727.1 - 2.5e-51 173.3 0.0 4.3e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN84727.1 - 7.8e-16 57.7 0.0 1e-15 57.3 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN84727.1 - 0.00048 19.9 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase FH2 PF02181.18 KZN84729.1 - 1.2e-85 287.6 1.9 1.2e-85 287.6 1.3 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KZN84729.1 - 2.3e-68 229.2 0.0 2.3e-68 229.2 0.0 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KZN84729.1 - 8.2e-53 178.7 1.9 4e-52 176.5 0.1 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain TrmE_N PF10396.4 KZN84730.1 - 7.1e-36 122.6 0.0 1.6e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KZN84730.1 - 6.2e-24 84.1 0.2 2.5e-23 82.2 0.1 2.1 1 1 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KZN84730.1 - 3.2e-17 62.5 0.0 5.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN84730.1 - 8.5e-05 21.8 0.1 0.00039 19.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KZN84730.1 - 8.9e-05 21.9 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KZN84730.1 - 9.9e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KZN84730.1 - 0.00028 21.3 0.1 0.0015 19.0 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KZN84730.1 - 0.099 12.2 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.2 KZN84731.1 - 0.05 13.7 0.2 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.1 KZN84731.1 - 1.9 8.3 6.7 9.9 6.1 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger Aminotran_5 PF00266.14 KZN84732.1 - 4.1e-28 98.1 0.0 3.6e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.1 KZN84732.1 - 0.024 13.9 0.0 0.084 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) NAD_binding_1 PF00175.16 KZN84733.1 - 1.5e-06 28.7 0.0 0.012 16.2 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN84733.1 - 3.8e-06 26.9 0.0 2.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KZN84733.1 - 0.0047 16.8 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.1 KZN84734.1 - 1.5e-62 211.5 39.1 2.6e-62 210.7 27.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84734.1 - 3.4e-28 98.2 25.1 3.4e-28 98.2 17.4 2.3 2 1 0 2 2 2 1 Amino acid permease NADHdeh_related PF10125.4 KZN84734.1 - 0.89 8.6 12.3 0.02 14.0 3.5 1.9 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Glyco_hydro_32N PF00251.15 KZN84735.1 - 5.2e-47 160.7 0.0 7.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN84735.1 - 2.6e-07 30.9 0.0 5.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KZN84735.1 - 0.0015 18.0 1.7 0.09 12.6 0.0 3.1 2 0 0 2 2 2 1 BNR/Asp-box repeat BNR_2 PF13088.1 KZN84735.1 - 0.0083 15.4 1.6 0.04 13.2 1.1 2.2 1 1 0 1 1 1 1 BNR repeat-like domain Sugar_tr PF00083.19 KZN84736.1 - 2.9e-80 270.0 12.5 3.5e-80 269.7 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84736.1 - 2e-23 82.6 29.1 3.3e-21 75.4 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TspO_MBR PF03073.10 KZN84736.1 - 0.26 10.8 13.4 0.014 14.9 3.9 2.5 2 0 0 2 2 2 0 TspO/MBR family Fungal_trans PF04082.13 KZN84737.1 - 4.3e-13 48.7 0.1 9.2e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84737.1 - 1.7e-09 37.3 9.5 1.7e-09 37.3 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KZN84738.1 - 5.1e-103 345.2 0.0 6.2e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Rep_fac_C PF08542.6 KZN84739.1 - 6.5e-21 74.1 0.0 1.7e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KZN84739.1 - 2.4e-11 43.9 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KZN84739.1 - 9.8e-07 28.5 0.0 9.8e-05 22.0 0.0 2.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KZN84739.1 - 2.6e-06 27.3 0.0 1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KZN84739.1 - 1.1e-05 24.3 0.0 0.084 11.5 0.0 2.3 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KZN84739.1 - 1.6e-05 24.1 0.1 4.9e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KZN84739.1 - 2.3e-05 24.4 0.1 0.00016 21.6 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KZN84739.1 - 8.6e-05 22.6 0.2 0.011 15.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KZN84739.1 - 0.00016 21.2 0.0 0.063 12.6 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain Viral_helicase1 PF01443.13 KZN84739.1 - 0.00052 19.6 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KZN84739.1 - 0.0016 18.1 0.0 0.0049 16.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KZN84739.1 - 0.0022 17.5 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 KZN84739.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit KTI12 PF08433.5 KZN84739.1 - 0.0049 16.1 0.0 0.009 15.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 KZN84739.1 - 0.0072 15.1 0.1 0.018 13.8 0.0 1.6 1 1 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 KZN84739.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.1 KZN84739.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KZN84739.1 - 0.018 14.1 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KZN84739.1 - 0.022 14.1 0.2 0.3 10.4 0.0 2.7 3 1 1 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN84739.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KZN84739.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KZN84739.1 - 0.047 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KZN84739.1 - 0.055 12.9 0.2 1.8 7.9 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KZN84739.1 - 0.059 13.0 0.1 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Imm29 PF15575.1 KZN84740.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 29 DUF410 PF04190.8 KZN84741.1 - 1.2e-45 156.1 0.0 1.5e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 KZN84742.1 - 1.2e-29 101.9 0.0 3.2e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 KZN84743.1 - 3e-51 173.8 0.4 5.2e-51 173.1 0.3 1.3 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.2 KZN84743.1 - 5.4e-06 26.4 2.6 9.5e-06 25.6 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN84743.1 - 1.3e-05 25.2 5.4 2.3e-05 24.4 3.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 KZN84743.1 - 1.9e-05 25.4 2.9 0.00012 22.9 1.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN84743.1 - 0.00015 21.6 0.1 0.0098 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN84743.1 - 0.00039 20.7 0.8 0.037 14.3 0.5 2.9 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 KZN84743.1 - 0.0014 17.8 0.1 0.0045 16.1 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase AAA_25 PF13481.1 KZN84743.1 - 0.019 14.3 0.0 0.31 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.2 KZN84743.1 - 0.021 14.9 2.4 0.052 13.6 1.7 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Las1 PF04031.8 KZN84743.1 - 0.024 14.2 0.1 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 Las1-like AAA_22 PF13401.1 KZN84743.1 - 0.029 14.5 0.0 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KZN84743.1 - 0.059 13.3 0.4 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN84743.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2 PF00096.21 KZN84743.1 - 0.17 12.3 1.4 0.34 11.3 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type MUG113 PF13455.1 KZN84743.1 - 0.21 12.0 1.9 0.64 10.5 1.3 1.9 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 ABC_tran PF00005.22 KZN84744.1 - 2.2e-17 63.6 0.1 1.9e-16 60.6 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KZN84744.1 - 9.2e-11 42.2 0.3 3.8e-05 23.7 0.1 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 KZN84744.1 - 4e-05 22.8 0.0 0.088 11.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain PduV-EutP PF10662.4 KZN84744.1 - 0.00028 20.3 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KZN84744.1 - 0.00036 20.0 0.1 0.00064 19.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KZN84744.1 - 0.00072 18.8 0.1 0.3 10.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 KZN84744.1 - 0.0017 15.8 0.2 0.0023 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_25 PF13481.1 KZN84744.1 - 0.0063 15.9 0.1 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KZN84744.1 - 0.01 16.1 0.1 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KZN84744.1 - 0.015 15.1 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN84744.1 - 0.018 15.8 0.3 0.04 14.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN84744.1 - 0.024 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KZN84744.1 - 0.032 14.1 0.3 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KZN84744.1 - 0.035 13.5 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KZN84744.1 - 0.057 13.4 1.4 0.1 12.5 0.9 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KZN84744.1 - 0.076 13.1 0.7 0.51 10.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KZN84744.1 - 0.11 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 KZN84744.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.1 KZN84744.1 - 0.13 11.8 0.5 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KZN84744.1 - 0.15 12.2 0.2 0.76 9.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 KZN84744.1 - 0.16 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KZN84744.1 - 0.16 11.6 0.4 0.92 9.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 KZN84745.1 - 1.8e-64 211.4 22.5 4.2e-09 35.9 0.0 12.9 13 0 0 13 13 13 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 KZN84745.1 - 1.2e-06 28.2 0.1 0.35 10.6 0.0 6.0 8 0 0 8 8 8 2 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.6 KZN84746.1 - 8.4e-35 118.7 0.1 9.6e-35 118.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KZN84746.1 - 0.00072 19.9 0.0 0.00088 19.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.13 KZN84747.1 - 7.8e-63 211.5 0.1 1.2e-62 210.9 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KZN84747.1 - 1.2e-22 80.7 1.2 2e-22 79.9 0.9 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KZN84747.1 - 1.3e-05 25.9 1.8 0.0011 19.7 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KZN84747.1 - 0.00066 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KZN84747.1 - 0.0048 16.1 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 KZN84747.1 - 0.05 13.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Porin_3 PF01459.17 KZN84748.1 - 1.3e-78 264.0 0.0 1.5e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 KZN84748.1 - 0.032 13.6 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 KZN84749.1 - 1.3e-64 217.8 0.0 1.6e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84749.1 - 4.3e-25 88.2 0.0 5.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84749.1 - 1e-06 27.9 0.0 4.5e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN84749.1 - 0.00068 19.4 0.1 0.019 14.6 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family rpo132 PF12415.3 KZN84749.1 - 0.029 13.3 0.7 0.91 8.5 0.0 2.6 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Choline_kinase PF01633.15 KZN84749.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.6 KZN84750.1 - 2.4e-82 275.0 0.1 4.2e-82 274.2 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KZN84750.1 - 1.2e-61 208.2 0.0 1.8e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like DUF2326 PF10088.4 KZN84750.1 - 0.05 13.2 0.3 1 9.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2326) zf-C2H2 PF00096.21 KZN84751.1 - 1.7e-19 68.8 21.7 5.5e-05 23.2 0.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN84751.1 - 5.6e-17 61.1 23.7 1.5e-08 34.5 1.7 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN84751.1 - 2.3e-15 55.6 19.1 0.0023 18.1 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 KZN84751.1 - 0.00062 19.8 7.4 0.14 12.3 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KZN84751.1 - 0.017 14.7 5.5 1.2 8.7 0.0 3.4 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger CHORD PF04968.7 KZN84751.1 - 2.5 8.3 11.6 14 6.0 1.2 3.5 2 1 1 3 3 3 0 CHORD WD40 PF00400.27 KZN84752.1 - 2.4e-73 239.6 9.2 8.4e-12 44.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KZN84752.1 - 2.2e-26 91.8 11.1 3.2e-26 91.3 7.7 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 KZN84752.1 - 7.2e-05 21.2 0.3 0.00084 17.7 0.1 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 KZN84752.1 - 0.00033 18.9 0.3 0.16 10.0 0.0 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KZN84752.1 - 0.00049 19.8 0.0 0.031 13.9 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KZN84752.1 - 0.031 13.3 0.0 4.9 6.1 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FA_hydroxylase PF04116.8 KZN84753.1 - 5e-13 49.4 22.4 8.5e-13 48.7 12.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Methyltransf_26 PF13659.1 KZN84754.1 - 5.2e-12 45.8 0.0 9e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN84754.1 - 1.3e-09 38.6 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN84754.1 - 9.8e-09 34.8 0.0 1.3e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 KZN84754.1 - 3.6e-08 33.1 0.0 6.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84754.1 - 9.9e-05 22.6 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KZN84754.1 - 0.00041 19.5 0.0 0.00056 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KZN84754.1 - 0.00095 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KZN84754.1 - 0.0018 17.9 0.0 0.0019 17.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84754.1 - 0.024 15.1 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KZN84754.1 - 0.026 15.0 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.7 KZN84754.1 - 0.029 13.5 0.0 0.081 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF890) GIDA_assoc_3 PF13932.1 KZN84754.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 GidA associated domain 3 Methyltransf_23 PF13489.1 KZN84754.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KZN84754.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.4 KZN84754.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Asp PF00026.18 KZN84755.1 - 4.8e-70 236.3 9.4 5.8e-70 236.0 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KZN84755.1 - 2e-09 37.6 3.6 2.3e-09 37.3 1.4 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KZN84755.1 - 6e-07 29.8 1.5 0.0064 16.9 0.3 3.8 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KZN84755.1 - 0.00016 21.2 0.1 0.0016 18.0 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KZN84755.1 - 0.031 14.0 2.3 5.5 6.8 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KZN84755.1 - 0.13 12.1 1.2 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease tRNA-synt_1b PF00579.20 KZN84756.1 - 3.3e-75 252.9 0.0 4.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 KZN84757.1 - 2.4e-25 88.1 0.0 4.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.15 KZN84758.1 - 2.7e-47 160.6 0.1 3.8e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 KZN84759.1 - 2e-30 104.7 2.4 5.9e-30 103.2 1.6 1.9 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 KZN84760.1 - 3.7e-19 68.5 0.6 6.2e-19 67.8 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KZN84760.1 - 1.8e-12 47.1 0.1 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KZN84760.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KZN84761.1 - 3.6e-116 387.8 1.8 7.9e-116 386.7 1.3 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 KZN84761.1 - 0.0005 19.8 7.9 0.00097 18.9 0.9 3.2 2 1 1 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.6 KZN84761.1 - 0.00066 19.5 1.6 0.00066 19.5 1.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 KZN84761.1 - 0.0033 17.3 4.2 0.011 15.7 1.6 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 KZN84761.1 - 0.0057 15.5 3.4 0.0057 15.5 2.3 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KZN84761.1 - 0.016 14.8 1.0 0.016 14.8 0.7 3.1 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain Vps51 PF08700.6 KZN84761.1 - 0.054 13.3 1.5 0.2 11.4 0.2 2.7 2 0 0 2 2 2 0 Vps51/Vps67 RRM_2 PF04059.7 KZN84762.1 - 2.7e-33 113.8 0.1 8.3e-33 112.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 KZN84762.1 - 6.7e-06 25.6 0.0 0.03 13.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84762.1 - 0.017 15.0 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.2 KZN84762.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain SprA-related PF12118.3 KZN84763.1 - 0.0056 16.0 0.1 0.0085 15.4 0.1 1.2 1 0 0 1 1 1 1 SprA-related family DUF2413 PF10310.4 KZN84763.1 - 7 5.3 9.6 9.1 4.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Phosphodiest PF01663.17 KZN84764.1 - 2.5e-16 59.9 2.6 5.2e-15 55.6 1.9 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KZN84764.1 - 4.4e-06 26.1 0.0 6.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KZN84764.1 - 0.028 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 KZN84764.1 - 0.28 9.5 0.0 0.39 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2423 PF10338.4 KZN84765.1 - 1.1e-18 66.8 3.1 1.1e-18 66.8 2.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) RR_TM4-6 PF06459.7 KZN84765.1 - 0.61 9.9 4.5 0.67 9.7 3.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PINIT PF14324.1 KZN84766.1 - 6.6e-41 139.7 0.4 1.3e-40 138.7 0.3 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KZN84766.1 - 1.9e-21 75.2 7.3 3.3e-21 74.5 5.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KZN84766.1 - 1.2e-06 27.8 2.9 3.3e-06 26.5 2.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KZN84766.1 - 2.1e-05 23.9 0.0 5.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain TRAPP PF04051.11 KZN84767.1 - 2.5e-45 153.7 0.0 2.8e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 KZN84767.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Alpha helical Porin B Ldh_1_N PF00056.18 KZN84768.1 - 6.5e-45 152.4 0.1 9.5e-45 151.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KZN84768.1 - 2.7e-40 137.9 0.0 3.7e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KZN84768.1 - 6.1e-05 21.8 0.0 9.3e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.12 KZN84769.1 - 2.2e-43 147.3 1.7 2.8e-43 147.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 KZN84770.1 - 9e-46 154.8 0.0 1e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.17 KZN84771.1 - 2e-33 113.8 0.0 1.5e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84771.1 - 3.7e-21 74.8 0.1 3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84771.1 - 3e-16 59.0 0.0 7.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KZN84771.1 - 0.0094 15.6 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 1 Limkain b1 OB_RNB PF08206.6 KZN84771.1 - 0.015 14.7 0.1 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain CMV_1a_C PF12503.3 KZN84771.1 - 0.063 13.0 0.2 5.4 6.8 0.0 2.6 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein C terminal DUF605 PF04652.11 KZN84771.1 - 0.31 10.3 12.1 0.37 10.1 8.4 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KZN84771.1 - 1.7 6.7 14.9 2.3 6.3 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tom7 PF08038.7 KZN84772.1 - 3.8e-20 71.0 0.2 4.3e-20 70.8 0.2 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 KZN84773.1 - 3.8e-42 141.8 1.1 2.3e-21 75.3 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein SWIRM PF04433.12 KZN84774.1 - 6e-15 55.1 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.10 KZN84775.1 - 2.8e-98 328.4 0.0 3.6e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 KZN84775.1 - 0.14 12.3 2.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Peptidase_M43 PF05572.8 KZN84776.1 - 1.4e-13 50.7 0.1 3.3e-13 49.5 0.1 1.7 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KZN84776.1 - 3.2e-05 23.9 5.5 8e-05 22.6 3.8 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KZN84776.1 - 0.0019 18.7 0.3 0.0053 17.2 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KZN84776.1 - 0.012 15.7 2.1 0.018 15.1 1.4 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KZN84776.1 - 0.084 12.3 2.0 0.13 11.8 1.4 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPT16 PF08644.6 KZN84777.1 - 2.9e-59 199.2 0.0 6.6e-59 198.1 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KZN84777.1 - 1.6e-55 187.1 0.1 5.3e-55 185.3 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KZN84777.1 - 6.7e-25 87.8 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KZN84777.1 - 9.5e-20 70.3 0.0 2.5e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Arc_PepC PF06819.6 KZN84777.1 - 0.0055 16.6 0.0 0.47 10.3 0.0 2.9 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminal Domain Mito_carr PF00153.22 KZN84778.1 - 1.4e-19 69.6 5.2 6.2e-15 54.6 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.19 KZN84779.1 - 8.2e-100 334.4 13.2 1.1e-99 334.0 9.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84779.1 - 9.4e-29 100.2 30.0 2e-24 86.0 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN84779.1 - 8.8e-10 37.5 17.9 5.1e-06 25.1 3.9 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein PMT PF02366.13 KZN84780.1 - 1.5e-83 279.9 14.5 1.5e-83 279.9 10.1 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KZN84780.1 - 1.2e-39 135.8 0.3 1.6e-39 135.4 0.2 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 KZN84781.1 - 7.9e-48 161.9 0.0 3.2e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KZN84781.1 - 1.4e-15 57.8 0.0 2.1e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN84781.1 - 5.6e-11 42.0 0.0 1.9e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN84781.1 - 1.6e-09 37.4 0.0 4.2e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN84781.1 - 6.1e-05 22.2 0.0 0.00021 20.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN84781.1 - 0.00017 21.4 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KZN84781.1 - 0.0065 16.0 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN84781.1 - 0.0066 16.5 0.1 0.043 13.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain Flu_M1_C PF08289.6 KZN84781.1 - 0.045 13.7 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain MAGE_N PF12440.3 KZN84781.1 - 0.083 13.1 0.4 0.19 12.0 0.3 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal AAA_16 PF13191.1 KZN84781.1 - 0.18 11.7 0.2 0.42 10.5 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain Choline_transpo PF04515.7 KZN84782.1 - 8.2e-08 31.3 15.2 8.2e-08 31.3 10.5 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter Bacteriocin_IIc PF10439.4 KZN84782.1 - 5.3 7.2 7.5 18 5.5 5.2 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Aldo_ket_red PF00248.16 KZN84784.1 - 4.3e-47 160.2 0.1 5.1e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 KZN84785.1 - 2.3e-114 382.3 0.0 2.8e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family F-box PF00646.28 KZN84786.1 - 2.3e-06 27.1 0.3 2.3e-06 27.1 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KZN84786.1 - 2.1e-05 24.1 0.1 4.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 KZN84786.1 - 0.00011 21.9 0.7 0.4 10.6 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat SAE2 PF08573.5 KZN84787.1 - 3.6e-29 101.3 4.4 4.5e-29 100.9 0.0 3.2 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Histone_HNS PF00816.16 KZN84787.1 - 0.00062 20.2 4.4 0.0093 16.4 0.3 3.0 2 0 0 2 2 2 1 H-NS histone family MAGUK_N_PEST PF10608.4 KZN84787.1 - 0.028 14.7 1.0 0.089 13.2 0.7 1.8 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK GAS PF13851.1 KZN84787.1 - 0.15 11.2 4.8 0.35 10.0 3.3 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 KZN84787.1 - 2.1 8.3 13.2 12 5.9 1.0 3.8 3 0 0 3 3 3 0 bZIP transcription factor Pex16 PF08610.5 KZN84788.1 - 9.6e-115 383.1 0.0 1.1e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 KZN84789.1 - 1.1e-45 155.7 0.0 1.5e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Mif2_N PF15624.1 KZN84790.1 - 2.6e-39 134.9 3.5 2.6e-39 134.9 2.4 4.1 4 2 1 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 KZN84790.1 - 5.5e-37 125.6 0.6 9.6e-37 124.8 0.4 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KZN84790.1 - 3.9e-07 29.4 0.0 9.2e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.20 KZN84791.1 - 1.3e-27 95.2 0.0 2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KZN84791.1 - 4.1e-14 52.5 0.0 6.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KZN84791.1 - 4.2e-05 22.8 0.0 0.00016 20.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Methyltransf_11 PF08241.7 KZN84792.1 - 2.3e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN84792.1 - 1.7e-08 34.7 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84792.1 - 2.9e-08 33.5 0.0 9.9e-08 31.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN84792.1 - 1.8e-06 28.3 0.0 3.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN84792.1 - 4.3e-05 23.1 0.0 6.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KZN84792.1 - 0.0016 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 KZN84792.1 - 0.0038 17.8 0.0 0.0074 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KZN84792.1 - 0.019 13.6 0.0 0.067 11.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 KZN84792.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Myb_DNA-binding PF00249.26 KZN84793.1 - 2.4e-11 43.4 3.0 6.4e-09 35.7 0.0 3.2 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KZN84793.1 - 6.2e-07 29.4 4.7 0.0002 21.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.24 KZN84794.1 - 2.5e-21 75.9 0.0 5.2e-21 74.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN84794.1 - 1.1e-08 34.9 0.0 2.4e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.1 KZN84795.1 - 4.6e-40 136.2 0.5 9.5e-40 135.2 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KZN84795.1 - 4.6e-29 100.4 0.0 1e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NARP1 PF12569.3 KZN84795.1 - 0.074 11.7 4.7 0.13 10.9 3.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ADK PF00406.17 KZN84796.1 - 1.4e-59 200.2 0.0 1.9e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KZN84796.1 - 3.6e-14 52.1 0.0 1e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KZN84796.1 - 4.1e-06 26.7 0.0 8.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN84796.1 - 1.9e-05 25.4 0.0 2.9e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN84796.1 - 0.00091 19.5 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN84796.1 - 0.0081 15.2 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 KZN84796.1 - 0.09 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.1 KZN84796.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 KZN84796.1 - 0.15 11.9 0.9 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GFO_IDH_MocA PF01408.17 KZN84797.1 - 8.5e-18 65.0 0.1 1.3e-17 64.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN84797.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CTD_bind PF04818.8 KZN84798.1 - 0.0038 17.4 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 KZN84798.1 - 0.018 15.2 0.2 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 RRN7 PF11781.3 KZN84798.1 - 0.028 13.9 1.4 0.16 11.4 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 VHS PF00790.14 KZN84798.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 VHS domain zf-C2HC_2 PF13913.1 KZN84798.1 - 0.34 10.6 5.2 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HOOK PF05622.7 KZN84799.1 - 4.9e-24 84.1 38.1 4.9e-24 84.1 26.4 2.8 1 1 1 2 2 2 1 HOOK protein TPR_MLP1_2 PF07926.7 KZN84799.1 - 0.00097 18.8 12.6 0.00097 18.8 8.7 6.2 4 1 1 6 6 6 2 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 KZN84799.1 - 0.01 14.3 50.3 0.02 13.4 20.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.15 KZN84799.1 - 0.012 15.4 1.8 0.012 15.4 1.3 9.4 5 2 3 8 8 8 0 Prefoldin subunit DUF1411 PF07199.6 KZN84799.1 - 0.028 13.8 2.2 0.11 11.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Reo_sigmaC PF04582.7 KZN84799.1 - 0.24 10.5 18.1 0.025 13.7 1.5 3.4 2 2 1 3 3 3 0 Reovirus sigma C capsid protein HALZ PF02183.13 KZN84799.1 - 0.25 11.0 48.5 0.7 9.6 0.0 9.1 7 3 1 8 8 8 0 Homeobox associated leucine zipper Spc7 PF08317.6 KZN84799.1 - 1.3 7.6 66.5 0.13 10.9 5.4 4.8 3 1 2 5 5 5 0 Spc7 kinetochore protein CCDC155 PF14662.1 KZN84799.1 - 1.7 8.2 86.3 0.72 9.4 13.7 5.4 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 AAA_27 PF13514.1 KZN84799.1 - 2.4 5.6 64.7 0.027 12.1 23.3 3.0 1 1 1 3 3 3 0 AAA domain DivIVA PF05103.8 KZN84799.1 - 4.8 7.2 68.9 0.15 12.1 5.9 8.3 6 2 3 9 9 9 0 DivIVA protein Bacillus_HBL PF05791.6 KZN84799.1 - 6.2 6.1 44.7 0.056 12.8 3.1 6.0 2 2 2 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) Mito_carr PF00153.22 KZN84800.1 - 1.1e-27 95.4 1.9 2.3e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.11 KZN84801.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KZN84801.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KZN84802.1 - 1.9e-120 400.8 0.0 4.6e-120 399.6 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Mito_carr PF00153.22 KZN84803.1 - 3.2e-28 97.2 4.6 1.9e-12 46.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 KZN84804.1 - 8.4e-102 340.5 0.0 1e-101 340.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Amidohydro_1 PF01979.15 KZN84804.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family RRM_1 PF00076.17 KZN84805.1 - 3.7e-06 26.4 0.0 7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KZN84805.1 - 0.0018 18.4 0.0 0.0063 16.7 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_6 PF14259.1 KZN84805.1 - 0.0018 18.1 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84805.1 - 0.0023 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.15 KZN84806.1 - 2e-148 493.7 0.0 2.3e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KZN84806.1 - 5.5e-13 48.7 0.6 9.1e-13 47.9 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KZN84806.1 - 9.3e-09 34.4 0.2 1.4e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN84806.1 - 3.3e-08 32.8 0.1 5.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KZN84806.1 - 7.4e-06 25.3 0.0 1.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KZN84806.1 - 0.0005 18.4 0.1 0.00068 18.0 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KZN84806.1 - 0.016 13.9 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Sugar_tr PF00083.19 KZN84807.1 - 1.7e-77 260.9 22.0 2e-77 260.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84807.1 - 3.8e-20 71.9 40.2 3.2e-13 49.1 11.3 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KZN84807.1 - 3.1e-05 22.5 2.9 3.1e-05 22.5 2.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Fungal_trans PF04082.13 KZN84808.1 - 2.5e-08 33.1 0.6 4.5e-08 32.2 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HLH PF00010.21 KZN84809.1 - 4e-12 45.6 2.6 7.9e-12 44.6 1.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Septin PF00735.13 KZN84810.1 - 1.1e-12 47.6 0.0 4.9e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KZN84810.1 - 1.2e-05 25.2 0.0 2.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KZN84810.1 - 0.00046 19.3 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.13 KZN84810.1 - 0.002 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KZN84810.1 - 0.0023 17.7 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN84810.1 - 0.0048 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KZN84810.1 - 0.0081 15.8 0.1 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KZN84810.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 KZN84810.1 - 0.013 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 KZN84810.1 - 0.013 15.5 0.1 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN84810.1 - 0.014 16.1 0.0 0.028 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KZN84810.1 - 0.014 14.8 0.1 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 KZN84810.1 - 0.018 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KZN84810.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN84810.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 KZN84810.1 - 0.039 13.6 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 KZN84810.1 - 0.048 13.4 0.2 6.1 6.6 0.1 2.9 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.1 KZN84810.1 - 0.049 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KZN84810.1 - 0.051 12.4 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KZN84810.1 - 0.097 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 KZN84810.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 KZN84810.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KZN84810.1 - 0.11 12.0 0.1 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KZN84810.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KZN84810.1 - 0.27 9.9 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Peptidase_M16 PF00675.15 KZN84811.1 - 3.3e-20 72.3 0.0 8.3e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KZN84811.1 - 5e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.6 KZN84811.1 - 0.0023 16.8 0.0 0.0041 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Bac_DNA_binding PF00216.16 KZN84811.1 - 0.17 11.9 1.0 21 5.2 0.1 2.7 2 0 0 2 2 2 0 Bacterial DNA-binding protein RNA_pol_Rpc82 PF05645.8 KZN84812.1 - 5.5e-27 94.9 0.0 1e-22 80.9 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KZN84812.1 - 1.1e-16 60.4 2.6 1.3e-09 37.7 0.1 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KZN84812.1 - 0.00014 21.3 0.2 0.0012 18.2 0.0 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit HTH_27 PF13463.1 KZN84812.1 - 0.0037 17.5 0.0 0.62 10.4 0.0 3.1 3 0 0 3 3 3 1 Winged helix DNA-binding domain MARVEL PF01284.18 KZN84813.1 - 1.1e-22 80.4 15.9 1.3e-22 80.1 11.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain Kelch_5 PF13854.1 KZN84813.1 - 0.096 12.6 0.5 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Kelch motif AA_permease PF00324.16 KZN84814.1 - 4.4e-132 440.8 48.5 5.3e-132 440.5 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN84814.1 - 2.4e-32 112.0 54.0 3e-32 111.7 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 KZN84814.1 - 0.02 13.8 0.9 0.43 9.5 0.0 3.0 2 2 1 3 3 3 0 Peptidase family M50 AMP-binding PF00501.23 KZN84815.1 - 4.3e-80 269.1 0.0 5.3e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GST_N_3 PF13417.1 KZN84816.1 - 3.2e-12 46.4 0.1 6.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN84816.1 - 1.2e-09 38.0 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN84816.1 - 6.1e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KZN84816.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Fructosamin_kin PF03881.9 KZN84817.1 - 2.6e-31 108.6 0.0 3.4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KZN84817.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family NACHT PF05729.7 KZN84818.1 - 8e-07 28.8 0.1 1.8e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KZN84818.1 - 1.5e-05 24.7 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KZN84818.1 - 6.2e-05 22.3 0.2 0.00053 19.3 0.0 2.5 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KZN84818.1 - 6.6e-05 22.8 0.0 0.00023 21.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KZN84818.1 - 0.00016 21.8 0.4 0.037 14.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN84818.1 - 0.00023 21.1 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KZN84818.1 - 0.00064 18.6 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_5 PF12695.2 KZN84818.1 - 0.0069 16.1 0.0 0.021 14.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2075 PF09848.4 KZN84818.1 - 0.0085 15.0 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KZN84818.1 - 0.014 15.0 0.0 0.056 13.1 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KZN84818.1 - 0.015 15.2 0.0 0.45 10.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KZN84818.1 - 0.023 14.4 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase LCAT PF02450.10 KZN84818.1 - 0.027 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0565 PF10561.4 KZN84818.1 - 0.044 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 AAA PF00004.24 KZN84818.1 - 0.048 13.8 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KZN84818.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AA_permease_2 PF13520.1 KZN84819.1 - 9.1e-45 152.9 39.7 1.1e-44 152.7 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84819.1 - 7.7e-18 64.0 36.7 1e-17 63.6 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease ketoacyl-synt PF00109.21 KZN84820.1 - 6.9e-75 251.7 0.0 2.1e-74 250.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN84820.1 - 3.5e-51 173.4 0.1 6.9e-51 172.4 0.1 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KZN84820.1 - 2.1e-49 168.6 0.0 3.7e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KZN84820.1 - 2.8e-45 154.2 0.0 1.2e-44 152.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KZN84820.1 - 6.3e-41 140.4 0.0 1.1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KZN84820.1 - 5.5e-30 103.6 0.0 1.5e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KZN84820.1 - 5.7e-17 62.0 0.0 2e-16 60.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN84820.1 - 4.1e-15 55.8 0.0 1.1e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN84820.1 - 3.7e-11 42.8 0.0 8.2e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN84820.1 - 9.3e-11 42.0 0.0 2.5e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN84820.1 - 4.4e-08 32.5 0.0 9.7e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KZN84820.1 - 4.7e-08 33.5 0.0 3.4e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 KZN84820.1 - 3.1e-06 26.3 0.0 6.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 KZN84820.1 - 0.0082 15.1 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase PP-binding PF00550.20 KZN84820.1 - 0.033 14.4 0.1 0.08 13.2 0.1 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF3458 PF11940.3 KZN84820.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) F420_oxidored PF03807.12 KZN84820.1 - 0.1 13.0 0.1 0.54 10.7 0.0 2.3 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent DREV PF05219.7 KZN84820.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 KZN84820.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.11 KZN84822.1 - 2e-19 69.5 21.1 2e-19 69.5 14.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily E1_dh PF00676.15 KZN84824.1 - 5.7e-109 363.4 0.7 6.7e-109 363.2 0.5 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KZN84824.1 - 0.038 12.9 0.0 0.079 11.8 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HSP90 PF00183.13 KZN84826.1 - 2.5e-252 838.0 31.3 2.9e-252 837.8 21.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KZN84826.1 - 2.4e-10 40.1 0.0 4.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KZN84826.1 - 5.3e-10 39.0 0.2 5.3e-10 39.0 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 KZN84826.1 - 0.17 11.3 1.7 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF399 Peptidase_S10 PF00450.17 KZN84826.1 - 0.46 9.5 0.0 0.46 9.5 0.0 2.2 1 1 0 2 2 2 0 Serine carboxypeptidase Tom37_C PF11801.3 KZN84826.1 - 1.3 8.9 11.4 5.9 6.7 2.9 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1510 PF07423.6 KZN84826.1 - 5.8 6.2 26.3 0.17 11.1 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NTF2 PF02136.15 KZN84827.1 - 8.4e-26 90.6 0.2 1.5e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KZN84827.1 - 1.1e-07 31.3 0.0 2.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84827.1 - 0.00052 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84827.1 - 0.0021 17.8 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN84827.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif TPR_11 PF13414.1 KZN84829.1 - 6.5e-06 25.6 5.7 0.92 9.2 0.0 4.9 3 2 2 5 5 5 3 TPR repeat TPR_17 PF13431.1 KZN84829.1 - 0.13 12.5 1.2 12 6.3 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84829.1 - 1.5 9.5 18.6 4.5 8.0 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KZN84829.1 - 4.4 7.3 10.2 1.4 8.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 KZN84830.1 - 6.6e-29 100.0 2.6 1e-28 99.5 1.8 1.3 1 0 0 1 1 1 1 Nnf1 Dicty_CAR PF05462.6 KZN84830.1 - 8e-09 34.8 11.1 1.3e-08 34.1 7.7 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KZN84830.1 - 1.2e-07 31.0 12.5 2.8e-07 29.8 8.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KZN84830.1 - 1.3e-07 31.4 11.3 2e-07 30.8 7.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Pkinase PF00069.20 KZN84831.1 - 2.8e-75 252.8 0.0 3.2e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84831.1 - 1.6e-36 125.6 0.0 2.2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN84831.1 - 0.00012 21.1 0.3 0.0018 17.2 0.0 2.6 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 KZN84831.1 - 0.0097 14.9 0.6 0.02 13.9 0.1 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KZN84831.1 - 0.031 13.1 0.0 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.18 KZN84831.1 - 0.045 13.4 0.1 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family SIR2 PF02146.12 KZN84832.1 - 4.3e-30 104.7 0.0 6.4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 KZN84833.1 - 9.3e-63 211.9 0.2 1.1e-62 211.6 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 KZN84833.1 - 0.052 12.1 0.1 0.078 11.5 0.1 1.2 1 0 0 1 1 1 0 Cation transport protein PAP2 PF01569.16 KZN84833.1 - 7.6 6.2 8.3 0.89 9.2 2.2 2.0 3 0 0 3 3 3 0 PAP2 superfamily FGGY_C PF02782.11 KZN84834.1 - 4.6e-31 107.9 0.0 7.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KZN84834.1 - 1.5e-22 80.0 0.0 5.5e-13 48.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 KZN84835.1 - 2.5e-40 137.8 0.2 4.2e-39 133.8 0.0 3.3 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KZN84835.1 - 0.0033 17.3 0.4 3.8 7.8 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat GFA PF04828.9 KZN84837.1 - 3.9e-22 78.0 0.3 5.8e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KZN84837.1 - 0.084 12.1 0.1 0.084 12.1 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Sgf11 PF08209.6 KZN84837.1 - 0.54 9.6 3.8 0.71 9.2 0.7 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 KZN84837.1 - 0.56 9.7 6.7 0.38 10.3 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KZN84837.1 - 1.5 8.3 5.4 1.7 8.1 0.2 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-Mss51 PF13824.1 KZN84837.1 - 2 8.3 4.6 5.5 6.9 0.7 2.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Esterase PF00756.15 KZN84838.1 - 3.5e-55 187.1 0.0 4.4e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KZN84838.1 - 9.2e-07 28.7 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KZN84838.1 - 1.6e-06 27.5 0.0 0.00011 21.5 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KZN84838.1 - 6.2e-05 22.3 0.1 0.00013 21.2 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KZN84838.1 - 8.8e-05 22.4 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KZN84838.1 - 0.0015 17.5 0.0 0.0029 16.5 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 KZN84838.1 - 0.0023 16.4 0.0 0.0034 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 KZN84838.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KZN84838.1 - 0.028 13.9 0.1 0.33 10.4 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KZN84838.1 - 0.058 12.9 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.11 KZN84838.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 KZN84838.1 - 0.14 10.9 0.0 0.46 9.2 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Peptidase_C50 PF03568.12 KZN84839.1 - 1.2e-126 422.4 0.0 3e-126 421.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 TPR_2 PF07719.12 KZN84839.1 - 8.4e-06 25.3 4.4 1 9.4 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat CHAT PF12770.2 KZN84839.1 - 1.8e-05 24.0 0.5 0.0032 16.6 0.0 3.4 2 1 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 KZN84839.1 - 0.00011 22.0 20.5 0.013 15.4 1.3 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN84839.1 - 0.0032 17.0 6.5 2.2 8.0 0.0 5.2 6 0 0 6 6 6 2 TPR repeat TPR_14 PF13428.1 KZN84839.1 - 0.0081 16.7 11.9 9.4 7.1 0.0 7.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KZN84839.1 - 0.015 15.1 0.4 4.9 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84839.1 - 0.042 13.4 1.4 34 4.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84839.1 - 0.066 13.0 0.2 29 4.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Moulting_cycle PF04870.11 KZN84840.1 - 0.85 8.6 7.4 0.95 8.4 4.8 1.3 1 1 0 1 1 1 0 Moulting cycle Mito_carr PF00153.22 KZN84841.1 - 6.7e-75 246.9 0.1 9.6e-26 89.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 KZN84841.1 - 1.5e-12 46.2 5.0 1.2e-06 27.8 0.1 4.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KZN84841.1 - 9.7e-12 43.3 3.2 1.7e-06 26.8 0.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KZN84841.1 - 1.4e-11 44.3 2.7 8.4e-07 29.0 0.7 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KZN84841.1 - 5.9e-09 35.4 2.6 0.84 9.3 0.0 5.2 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 KZN84841.1 - 2e-08 33.2 5.8 1.7e-05 23.9 0.2 3.8 4 0 0 4 4 4 2 EF hand Auxin_repressed PF05564.7 KZN84842.1 - 0.16 12.6 3.0 0.19 12.3 2.1 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein Peptidase_M22 PF00814.20 KZN84843.1 - 3.7e-43 147.9 0.0 2.5e-42 145.2 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.11 KZN84843.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain zf-HC5HC2H_2 PF13832.1 KZN84844.1 - 4.8e-32 110.2 5.2 4.8e-32 110.2 3.6 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 KZN84844.1 - 2.2e-30 106.0 0.0 4.8e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 KZN84844.1 - 1.6e-26 92.2 1.8 1.6e-26 92.2 1.3 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KZN84844.1 - 3.8e-15 54.8 8.4 5.2e-14 51.2 1.5 2.5 2 0 0 2 2 2 2 PHD-finger PHD PF00628.24 KZN84844.1 - 8.9e-10 38.1 19.8 6.4e-08 32.1 6.6 2.6 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KZN84844.1 - 0.35 10.6 19.3 0.035 13.8 1.2 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KZN84844.1 - 1.1 9.3 19.2 0.024 14.6 2.1 2.6 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KZN84844.1 - 4.4 7.1 14.8 3.4 7.4 4.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.17 KZN84845.1 - 1.4e-20 72.7 0.0 2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84845.1 - 1.9e-16 59.8 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84845.1 - 1.2e-11 44.2 0.0 1.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.8 KZN84846.1 - 3e-15 55.4 0.0 4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.6 KZN84847.1 - 1e-17 63.9 0.1 6.4e-17 61.4 0.0 2.3 3 0 0 3 3 3 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 KZN84848.1 - 2e-27 94.7 0.0 3.8e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KZN84848.1 - 9e-22 76.6 0.0 1.4e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KZN84848.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain OGG_N PF07934.7 KZN84849.1 - 5e-35 120.0 0.3 1.1e-34 118.9 0.2 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KZN84849.1 - 1.2e-14 54.4 0.0 1.5e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.17 KZN84850.1 - 5.1e-28 96.5 0.2 4.7e-12 45.3 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84850.1 - 3.2e-20 71.8 0.0 5e-05 23.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84850.1 - 1.3e-14 53.8 0.0 3e-07 30.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CARD PF00619.16 KZN84850.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Septin PF00735.13 KZN84851.1 - 4.9e-123 409.6 0.1 4.9e-123 409.6 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KZN84851.1 - 4.1e-07 29.9 0.0 8.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN84851.1 - 5e-06 26.0 0.6 0.00022 20.7 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KZN84851.1 - 2.6e-05 23.4 0.2 9e-05 21.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KZN84851.1 - 0.00015 20.9 0.8 0.00039 19.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 KZN84851.1 - 0.00024 21.4 2.0 0.022 15.0 0.0 2.8 2 1 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 KZN84851.1 - 0.00033 20.2 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain Ras PF00071.17 KZN84851.1 - 0.0013 18.1 0.1 0.015 14.7 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.1 KZN84851.1 - 0.0022 17.9 0.1 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KZN84851.1 - 0.0033 17.9 0.0 0.015 15.8 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 KZN84851.1 - 0.0034 17.5 0.0 0.012 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN84851.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KZN84851.1 - 0.016 14.6 2.2 0.019 14.4 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KZN84851.1 - 0.02 14.4 0.5 3.6 7.0 0.0 3.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KZN84851.1 - 0.06 12.9 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KZN84851.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Exonuc_VII_L PF02601.10 KZN84851.1 - 0.11 11.7 3.0 0.22 10.6 2.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit MobB PF03205.9 KZN84851.1 - 0.12 12.0 0.8 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 KZN84851.1 - 0.14 11.9 2.2 0.21 11.3 0.9 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat RNA_helicase PF00910.17 KZN84851.1 - 0.14 12.3 0.2 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 KZN84851.1 - 0.15 11.8 6.3 0.46 10.2 0.1 3.3 3 2 0 4 4 4 0 Dynamin family AAA_32 PF13654.1 KZN84851.1 - 0.18 10.3 9.6 0.43 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KZN84851.1 - 0.53 9.0 4.3 0.22 10.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SSrecog PF03531.9 KZN84852.1 - 1.4e-71 240.3 0.4 1.2e-70 237.3 0.2 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KZN84852.1 - 6.5e-29 99.7 0.1 1.5e-27 95.3 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Pyridox_oxidase PF01243.15 KZN84853.1 - 0.0008 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1381 PF07129.6 KZN84853.1 - 0.17 11.3 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) Rax2 PF12768.2 KZN84854.1 - 3.2e-100 334.9 14.2 5.8e-90 301.3 0.0 6.1 5 2 2 7 7 7 6 Cortical protein marker for cell polarity Zn_clus PF00172.13 KZN84855.1 - 1.4e-07 31.2 12.4 2.6e-07 30.4 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN84855.1 - 8e-06 24.6 0.8 9.7e-05 21.1 0.6 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain 7tm_2 PF00002.19 KZN84856.1 - 3.9 6.4 12.9 26 3.7 9.0 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) SH3_3 PF08239.6 KZN84857.1 - 0.00064 19.8 0.1 0.0011 19.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain UPF0121 PF03661.8 KZN84858.1 - 4e-12 45.8 4.8 5.7e-12 45.3 3.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.22 KZN84859.1 - 5.6e-62 205.4 0.1 2.4e-21 75.2 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Rho_N PF07498.7 KZN84860.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Herpes_BLLF1 PF05109.8 KZN84860.1 - 0.31 8.9 7.6 0.4 8.5 5.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TPK_catalytic PF04263.11 KZN84861.1 - 6.2e-22 77.4 0.1 4.8e-19 68.1 0.0 2.9 2 1 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KZN84861.1 - 3.7e-20 71.4 0.0 6.7e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 KZN84862.1 - 1.4e-07 31.2 4.4 2.3e-07 30.5 3.0 1.4 1 0 0 1 1 1 1 CHCH domain Death PF00531.17 KZN84862.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Death domain PfkB PF00294.19 KZN84863.1 - 8.3e-15 54.6 0.0 1.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Methyltransf_2 PF00891.13 KZN84864.1 - 1.2e-30 106.5 0.2 4.8e-30 104.5 0.0 2.0 2 1 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 KZN84864.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain HTH_27 PF13463.1 KZN84864.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 KZN84864.1 - 0.1 12.7 0.0 0.52 10.4 0.0 2.1 3 0 0 3 3 3 0 Transcriptional regulator DUF3671 PF12420.3 KZN84865.1 - 2 8.4 6.1 3.2 7.7 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function ABC2_membrane_5 PF13346.1 KZN84865.1 - 2.7 7.2 20.3 0.18 11.0 9.4 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein ADH_N PF08240.7 KZN84866.1 - 3.1e-11 42.9 0.2 8.3e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN84866.1 - 1.6e-09 37.3 0.2 3.4e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L1 PF00687.16 KZN84867.1 - 1.7e-54 184.4 6.2 1.7e-54 184.4 4.3 1.9 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family ETF PF01012.16 KZN84868.1 - 8.5e-42 142.6 0.5 1.7e-41 141.6 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KZN84868.1 - 2.6e-34 116.7 0.1 5.1e-34 115.7 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.24 KZN84869.1 - 1.3e-11 44.8 0.0 3.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN84869.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KZN84869.1 - 4e-05 23.3 0.0 9.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KZN84869.1 - 5.1e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KZN84869.1 - 0.00018 21.2 0.0 0.00073 19.2 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KZN84869.1 - 0.00056 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN84869.1 - 0.0012 19.6 0.0 0.0051 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KZN84869.1 - 0.0028 16.4 0.0 0.0057 15.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 KZN84869.1 - 0.0035 17.3 0.0 0.021 14.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KZN84869.1 - 0.0035 16.4 0.0 0.0081 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 KZN84869.1 - 0.0038 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN84869.1 - 0.059 13.6 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN84869.1 - 0.059 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KZN84869.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mucin PF01456.12 KZN84870.1 - 0.26 11.0 7.1 0.29 10.8 4.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Apc15p PF05841.6 KZN84870.1 - 0.28 11.9 8.6 0.31 11.7 6.0 1.0 1 0 0 1 1 1 0 Apc15p protein CAF-1_p150 PF11600.3 KZN84870.1 - 3.7 6.8 9.4 4.9 6.4 6.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 KZN84870.1 - 4.2 5.5 12.1 4.5 5.4 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein GST_C PF00043.20 KZN84871.1 - 4.6e-15 55.3 0.0 7.5e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN84871.1 - 2.7e-13 49.9 0.0 4.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN84871.1 - 4.5e-12 45.9 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN84871.1 - 1.8e-11 43.8 0.1 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN84871.1 - 1.4e-07 31.2 0.0 6.1e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN84871.1 - 1.3e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KZN84871.1 - 0.042 14.2 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain SUN PF03856.8 KZN84872.1 - 3.5e-97 324.5 6.1 5.8e-97 323.8 4.3 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Melittin PF01372.12 KZN84873.1 - 0.055 12.8 0.4 0.092 12.1 0.3 1.3 1 0 0 1 1 1 0 Melittin MIF4G PF02854.14 KZN84875.1 - 4.1e-61 206.0 0.0 7.4e-33 113.7 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KZN84875.1 - 9.7e-54 181.6 22.4 9.7e-54 181.6 15.6 3.2 3 1 0 3 3 3 1 Up-frameshift suppressor 2 TRI12 PF06609.8 KZN84876.1 - 1.2e-38 132.7 26.3 1.5e-38 132.3 18.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KZN84876.1 - 1.8e-08 33.4 46.8 1.8e-08 33.4 32.4 2.6 1 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KZN84877.1 - 2.8e-20 72.8 0.0 1e-19 71.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84877.1 - 1.7e-11 44.3 0.0 4.3e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN84877.1 - 1e-06 28.5 0.0 2.9e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN84877.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 KZN84878.1 - 7.5e-16 58.5 0.0 4.3e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84878.1 - 1.3e-07 31.6 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Methyltransf_26 PF13659.1 KZN84878.1 - 0.0034 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.5 KZN84878.1 - 0.072 12.7 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 KZN84880.1 - 5.8e-17 62.1 0.1 1.1e-16 61.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN84880.1 - 1.9e-05 24.4 0.1 3.9e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN84880.1 - 7.5e-05 22.6 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN84880.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KZN84880.1 - 0.003 17.3 0.3 1.6 8.5 0.1 2.4 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Terpene_synth_C PF03936.11 KZN84881.1 - 7.6e-21 74.5 0.1 5.6e-19 68.4 0.1 2.1 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain FAD_binding_4 PF01565.18 KZN84882.1 - 1.3e-19 70.0 1.9 2.1e-19 69.4 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KZN84883.1 - 5.5e-20 71.9 0.1 8.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN84883.1 - 9.6e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KZN84883.1 - 0.0003 20.8 0.1 0.00082 19.4 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KZN84883.1 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 KR domain DAO PF01266.19 KZN84883.1 - 0.027 13.3 0.0 0.03 13.2 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KZN84883.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN84883.1 - 0.094 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 KZN84883.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.9 KZN84883.1 - 0.14 10.5 0.2 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.17 KZN84884.1 - 7.5e-38 130.2 0.1 1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KZN84885.1 - 4.4e-48 163.9 0.0 5.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3237 PF11578.3 KZN84886.1 - 8.4e-18 64.1 0.0 9.5e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Transferase PF02458.10 KZN84887.1 - 6.5e-22 77.5 0.0 2.8e-13 49.1 0.0 2.6 3 0 0 3 3 3 2 Transferase family p450 PF00067.17 KZN84888.1 - 7.4e-70 235.7 0.0 8.7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Curto_V3 PF07436.6 KZN84889.1 - 0.04 14.0 0.1 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Curtovirus V3 protein p450 PF00067.17 KZN84890.1 - 2.3e-69 234.1 0.0 2.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KZN84891.1 - 1.8e-58 192.4 41.1 7.3e-13 47.8 1.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat NACHT PF05729.7 KZN84891.1 - 1.4e-14 54.0 0.0 4.7e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Nup160 PF11715.3 KZN84891.1 - 3.5e-05 22.1 0.1 0.033 12.3 0.0 3.7 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KZN84891.1 - 6.6e-05 21.3 0.0 0.00044 18.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain CDtoxinA PF03498.9 KZN84891.1 - 0.00016 21.0 0.0 3.5 6.9 0.0 4.3 2 2 2 4 4 4 1 Cytolethal distending toxin A/C family AAA_16 PF13191.1 KZN84891.1 - 0.00022 21.2 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain PQQ_2 PF13360.1 KZN84891.1 - 0.0056 16.1 0.2 0.15 11.4 0.0 3.0 2 1 0 2 2 2 1 PQQ-like domain CppA_N PF14506.1 KZN84891.1 - 0.17 11.5 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal Alpha-amylase PF00128.19 KZN84892.1 - 6.7e-36 124.2 0.1 1.1e-35 123.5 0.0 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KZN84892.1 - 0.00087 19.3 0.0 0.0027 17.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Alpha-amylase PF00128.19 KZN84893.1 - 3.2e-23 82.6 0.0 4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.11 KZN84894.1 - 0.72 8.5 18.2 2.5 6.7 8.4 2.6 1 1 1 2 2 2 0 Major Facilitator Superfamily Tad PF13400.1 KZN84894.1 - 0.83 9.7 7.3 1.1 9.3 1.5 2.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like VKOR PF07884.9 KZN84894.1 - 1.3 8.8 12.1 0.87 9.4 1.3 2.8 1 1 0 2 2 2 0 Vitamin K epoxide reductase family TspO_MBR PF03073.10 KZN84894.1 - 6 6.3 15.6 0.12 11.8 3.6 2.7 2 1 1 3 3 3 0 TspO/MBR family DUF3176 PF11374.3 KZN84895.1 - 8.7e-38 128.6 2.1 1.8e-37 127.6 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3112 PF11309.3 KZN84895.1 - 0.0045 16.8 1.0 0.0087 15.8 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) HlyIII PF03006.15 KZN84897.1 - 2.6e-44 151.2 16.5 3.2e-44 150.9 11.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 KZN84897.1 - 0.038 13.8 0.1 0.35 10.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF4149 PF13664.1 KZN84897.1 - 4.3 7.4 10.6 28 4.8 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4231 PF14015.1 KZN84897.1 - 8.6 6.3 9.2 6.4 6.8 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) S1-P1_nuclease PF02265.11 KZN84898.1 - 5.8e-71 239.0 0.1 6.8e-71 238.8 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease AA_permease_2 PF13520.1 KZN84899.1 - 8.5e-61 205.7 46.0 1e-60 205.4 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84899.1 - 4.3e-18 64.9 35.4 5.8e-18 64.4 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease Sdh_cyt PF01127.17 KZN84900.1 - 0.012 15.4 1.7 0.012 15.4 1.2 3.0 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3632 PF12311.3 KZN84901.1 - 8.8e-30 103.8 3.1 1.2e-29 103.4 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) T4_neck-protein PF11649.3 KZN84901.1 - 0.048 12.9 0.0 0.5 9.6 0.0 2.1 2 0 0 2 2 2 0 Virus neck protein F-box-like PF12937.2 KZN84903.1 - 0.00029 20.4 0.1 0.00055 19.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.2 KZN84904.1 - 2e-64 213.9 3.0 6.1e-18 64.9 0.0 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN84904.1 - 2.7e-41 137.3 0.6 1.1e-06 28.0 0.1 8.3 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KZN84904.1 - 5.5e-38 128.6 0.6 8.6e-12 45.2 0.0 6.4 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN84904.1 - 2.4e-37 126.0 0.4 4.6e-11 42.5 0.0 7.8 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN84904.1 - 3.9e-33 110.1 1.6 0.0004 20.3 0.0 8.4 8 0 0 8 8 8 7 Ankyrin repeat DUF2183 PF09949.4 KZN84905.1 - 4e-16 58.7 0.0 7.5e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Gly_transf_sug PF04488.10 KZN84906.1 - 3.5e-10 40.1 0.2 8.2e-10 39.0 0.1 1.6 1 1 1 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KZN84906.1 - 0.0068 14.9 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain SWIRM PF04433.12 KZN84909.1 - 3.6e-34 116.7 0.1 9e-34 115.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 KZN84909.1 - 5.7e-06 26.3 0.1 1.4e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN84909.1 - 9.4e-06 25.5 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KZN84909.1 - 0.032 13.7 5.1 0.26 10.8 3.5 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type V_ATPase_I PF01496.14 KZN84909.1 - 0.14 9.9 1.3 0.2 9.4 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.8 KZN84909.1 - 0.42 11.0 9.5 0.55 10.6 3.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ResIII PF04851.10 KZN84911.1 - 1.7e-22 80.1 0.0 3.2e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KZN84911.1 - 2.2e-12 46.6 0.0 5.8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN84911.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KZN84911.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 KZN84911.1 - 0.023 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ABC_tran PF00005.22 KZN84912.1 - 4.9e-46 156.4 0.1 1.7e-23 83.4 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KZN84912.1 - 1.5e-15 57.9 0.1 0.0017 18.3 0.1 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KZN84912.1 - 4.9e-13 48.8 0.1 9.1e-05 21.7 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KZN84912.1 - 2.3e-09 36.6 0.1 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KZN84912.1 - 4.5e-09 36.9 0.1 0.0021 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN84912.1 - 8.6e-08 32.3 0.0 0.0093 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN84912.1 - 3.5e-07 31.0 0.2 0.035 14.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KZN84912.1 - 3.7e-06 26.8 0.1 0.021 14.7 0.0 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KZN84912.1 - 7.3e-06 26.1 0.0 0.01 15.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 KZN84912.1 - 7.5e-06 25.4 0.0 0.094 12.1 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KZN84912.1 - 8.9e-06 25.5 0.0 0.041 13.8 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KZN84912.1 - 1.1e-05 24.7 0.0 0.0084 15.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KZN84912.1 - 1.8e-05 25.0 0.2 0.49 10.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 KZN84912.1 - 1.8e-05 25.1 0.0 0.024 15.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 KZN84912.1 - 3.8e-05 23.3 0.0 0.032 13.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KZN84912.1 - 4e-05 23.1 0.1 0.33 10.3 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain AAA_16 PF13191.1 KZN84912.1 - 5.6e-05 23.2 1.2 1 9.3 0.0 4.2 5 0 0 5 5 5 2 AAA ATPase domain AAA_15 PF13175.1 KZN84912.1 - 6.1e-05 22.2 3.2 0.6 9.0 0.0 3.7 2 2 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 KZN84912.1 - 7.8e-05 22.8 0.0 0.39 10.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 KZN84912.1 - 9.2e-05 22.3 0.0 0.21 11.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 KZN84912.1 - 0.00011 22.1 0.4 0.058 13.2 0.1 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_33 PF13671.1 KZN84912.1 - 0.00011 22.1 0.0 0.48 10.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.1 KZN84912.1 - 0.00015 20.4 0.0 0.41 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 KZN84912.1 - 0.00021 20.8 0.5 0.13 11.6 0.0 3.5 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KZN84912.1 - 0.00023 21.3 0.0 0.17 12.0 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KZN84912.1 - 0.0003 20.6 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 KZN84912.1 - 0.00043 19.9 0.2 0.83 9.3 0.0 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 KZN84912.1 - 0.00057 20.1 3.7 0.45 10.8 0.0 3.3 2 1 0 3 3 3 2 HEAT repeats AAA_25 PF13481.1 KZN84912.1 - 0.00069 19.0 0.0 1.2 8.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KZN84912.1 - 0.0015 18.1 0.0 1.7 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 KZN84912.1 - 0.0018 17.1 0.2 1 8.0 0.1 2.4 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 KZN84912.1 - 0.002 17.9 0.0 0.089 12.4 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 KZN84912.1 - 0.0043 16.5 0.0 0.64 9.4 0.0 2.8 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KZN84912.1 - 0.0046 16.4 0.4 0.14 11.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KZN84912.1 - 0.011 15.4 0.1 6.1 6.6 0.0 3.2 3 0 0 3 3 2 0 Part of AAA domain Septin PF00735.13 KZN84912.1 - 0.013 14.5 0.3 1.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Septin ATP_bind_1 PF03029.12 KZN84912.1 - 0.026 14.0 0.0 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KZN84912.1 - 0.027 13.3 0.5 8.2 5.2 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.17 KZN84912.1 - 0.029 13.2 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Arf PF00025.16 KZN84912.1 - 0.062 12.5 0.1 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.15 KZN84912.1 - 0.066 11.8 0.1 1.6 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit HEAT_EZ PF13513.1 KZN84912.1 - 0.42 11.1 4.0 1.1e+02 3.4 0.0 5.0 4 1 0 5 5 3 0 HEAT-like repeat Tmemb_14 PF03647.8 KZN84913.1 - 9.2e-26 90.0 3.1 1e-25 89.9 2.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PGAP1 PF07819.8 KZN84914.1 - 3.5e-84 281.8 0.0 5.9e-84 281.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KZN84914.1 - 5.6e-11 42.3 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN84914.1 - 1e-07 32.1 0.4 1.8e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KZN84914.1 - 0.0012 18.3 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.15 KZN84914.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KZN84914.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 KZN84914.1 - 0.02 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 KZN84914.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KZN84914.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.19 KZN84915.1 - 2.5e-36 125.2 14.7 5.3e-36 124.1 10.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN84915.1 - 4.9e-34 117.5 31.6 1.1e-31 109.9 13.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.10 KZN84916.1 - 0.00012 21.6 15.2 0.00021 20.8 10.5 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KZN84916.1 - 0.00088 18.9 2.4 0.0021 17.7 1.7 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KZN84916.1 - 0.019 14.5 11.0 0.043 13.4 7.6 1.5 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KZN84916.1 - 0.049 13.1 11.0 0.087 12.3 7.6 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF1269 PF06897.7 KZN84916.1 - 0.055 13.5 1.2 0.071 13.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) SNARE_assoc PF09335.6 KZN84916.1 - 0.089 13.0 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein SR-25 PF10500.4 KZN84916.1 - 0.26 10.7 15.2 0.34 10.3 10.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 KZN84916.1 - 1.5 6.9 17.0 1.6 6.8 11.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF755 PF05501.6 KZN84916.1 - 1.9 8.5 18.9 2.6 8.1 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 KZN84916.1 - 2.9 7.6 12.6 3.9 7.2 8.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF533 PF04391.7 KZN84916.1 - 7.2 5.9 10.0 0.11 11.9 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Complex1_LYR_1 PF13232.1 KZN84917.1 - 3.1e-06 27.2 0.5 7.5e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KZN84917.1 - 1.2e-05 25.0 0.4 2.7e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ank_4 PF13637.1 KZN84918.1 - 1e-13 51.3 0.3 1.6e-09 37.9 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN84918.1 - 6.1e-07 29.4 1.5 0.00014 21.9 0.1 3.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN84918.1 - 2.8e-06 27.5 0.1 0.0048 17.1 0.0 2.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN84918.1 - 0.0009 19.2 1.0 0.22 11.8 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.8 KZN84918.1 - 0.0028 17.2 0.3 0.015 14.9 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.25 KZN84918.1 - 0.49 10.2 3.4 2.4 8.1 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Cellulase PF00150.13 KZN84919.1 - 9.5e-31 107.0 2.3 2.3e-30 105.7 0.6 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 KZN84920.1 - 9.8e-11 41.1 0.6 4.5e-07 29.4 0.0 5.1 4 1 2 6 6 6 2 TPR repeat TPR_2 PF07719.12 KZN84920.1 - 0.0014 18.4 12.3 0.017 15.0 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN84920.1 - 0.0077 16.1 6.3 11 6.0 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN84920.1 - 0.014 15.5 0.0 1.8 8.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN84920.1 - 0.022 14.3 5.5 0.21 11.2 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN84920.1 - 0.044 13.5 0.9 2 8.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84920.1 - 0.052 13.3 1.5 46 4.1 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN84920.1 - 0.073 13.7 5.1 0.41 11.3 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KZN84920.1 - 0.18 12.1 6.5 1.9 8.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_10 PF05971.7 KZN84921.1 - 1.8e-59 201.3 0.0 2.4e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 KZN84921.1 - 1.9e-06 27.3 0.0 5.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KZN84921.1 - 6.2e-06 26.2 0.0 2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KZN84921.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KZN84921.1 - 0.0048 17.4 0.0 0.022 15.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 KZN84921.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.4 KZN84921.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 KZN84921.1 - 0.15 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MFS_1 PF07690.11 KZN84922.1 - 1.5e-43 148.9 36.4 2.1e-39 135.2 15.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN84922.1 - 2.3e-07 29.7 15.3 2.3e-07 29.7 10.6 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter Dabb PF07876.7 KZN84922.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain Ribonuc_L-PSP PF01042.16 KZN84925.1 - 1.7e-20 72.9 0.0 2e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4602 PF15375.1 KZN84926.1 - 0.00029 20.8 12.2 0.00029 20.8 8.4 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) BNIP2 PF12496.3 KZN84926.1 - 2.8 8.1 9.4 0.58 10.3 3.8 1.9 1 1 1 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 His_biosynth PF00977.16 KZN84927.1 - 3.4e-31 108.2 0.0 4.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein MARVEL PF01284.18 KZN84928.1 - 0.0064 16.3 0.6 0.0079 16.0 0.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain Yip1 PF04893.12 KZN84928.1 - 0.011 15.2 0.5 0.011 15.2 0.3 1.3 1 1 0 1 1 1 0 Yip1 domain TMEMspv1-c74-12 PF11044.3 KZN84928.1 - 0.094 12.2 1.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CoA_binding PF02629.14 KZN84929.1 - 4.6e-26 91.1 3.1 4.4e-25 88.0 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KZN84929.1 - 7e-22 77.6 0.1 1.1e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KZN84929.1 - 3.3e-07 29.9 0.0 7.3e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KZN84929.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain CDC45 PF02724.9 KZN84930.1 - 4.1 5.3 9.3 5.5 4.8 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Isochorismatase PF00857.15 KZN84931.1 - 8.7e-18 64.8 0.0 2.4e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Rogdi_lz PF10259.4 KZN84931.1 - 0.077 12.0 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF1388 PF07142.7 KZN84932.1 - 0.15 11.7 0.2 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) ADH_zinc_N PF00107.21 KZN84934.1 - 1.5e-31 108.6 1.1 2.8e-31 107.7 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN84934.1 - 7.4e-22 78.5 0.1 1.4e-21 77.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN84934.1 - 2.9e-11 43.0 0.0 9.5e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KZN84934.1 - 0.00099 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KZN84934.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KZN84934.1 - 0.053 12.6 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KZN84934.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FA_desaturase PF00487.19 KZN84935.1 - 7.6e-15 55.0 24.6 7.6e-15 55.0 17.0 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Prominin PF05478.6 KZN84935.1 - 0.2 9.1 0.0 0.3 8.5 0.0 1.1 1 0 0 1 1 1 0 Prominin Arylsulfotran_2 PF14269.1 KZN84936.1 - 4.2e-47 160.7 0.0 7e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN84936.1 - 7.4e-21 74.2 0.0 1.6e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PepSY PF03413.14 KZN84936.1 - 0.021 15.4 0.3 10 6.8 0.0 3.8 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain DUF455 PF04305.9 KZN84938.1 - 4.9e-103 343.7 0.0 6.1e-103 343.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KZN84938.1 - 1e-05 25.0 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KZN84938.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF605 PF04652.11 KZN84940.1 - 2.7 7.3 22.0 9 5.5 15.3 1.9 1 1 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KZN84941.1 - 7 4.8 6.8 7.8 4.6 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 KZN84941.1 - 7 5.6 7.0 9.2 5.2 4.8 1.1 1 0 0 1 1 1 0 BUD22 Amidohydro_3 PF07969.6 KZN84942.1 - 2.5e-51 175.1 1.8 2.9e-51 174.9 1.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN84942.1 - 5.5e-12 45.3 0.1 1.6e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN84942.1 - 3.8e-06 26.8 1.9 0.006 16.2 0.3 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KZN84942.1 - 0.02 14.9 0.4 0.02 14.9 0.3 3.3 1 1 2 3 3 3 0 Amidohydrolase MFS_1 PF07690.11 KZN84944.1 - 1.3e-31 109.6 30.6 1.3e-31 109.6 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.3 KZN84944.1 - 0.12 12.4 1.2 0.35 10.9 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) STE PF02200.11 KZN84945.1 - 8.4e-60 199.7 0.1 1.5e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KZN84945.1 - 7.7e-12 44.8 13.4 1.7e-06 28.0 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN84945.1 - 4.2e-10 39.2 10.3 0.00015 21.8 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN84945.1 - 1.6e-09 37.5 4.1 1.6e-09 37.5 2.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KZN84945.1 - 0.0059 16.4 0.2 0.039 13.8 0.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-TRAF PF02176.13 KZN84945.1 - 0.0064 16.8 2.1 0.015 15.6 1.5 1.6 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KZN84945.1 - 0.099 12.8 4.3 1.7 8.9 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KZN84945.1 - 0.12 12.1 4.9 2.1 8.0 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 KZN84945.1 - 0.24 11.5 3.1 0.63 10.2 2.1 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding MFS_2 PF13347.1 KZN84946.1 - 6.6e-08 31.3 11.4 6.6e-08 31.3 7.9 2.1 1 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 KZN84946.1 - 9.4e-05 21.2 3.3 0.00015 20.6 2.3 1.3 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.16 KZN84947.1 - 6.6e-66 222.3 40.9 8.5e-66 222.0 28.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pex14_N PF04695.8 KZN84947.1 - 0.42 10.6 2.1 34 4.4 0.2 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4396 PF14342.1 KZN84947.1 - 1.1 9.3 8.6 0.65 10.0 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) AA_permease_2 PF13520.1 KZN84948.1 - 2.1e-52 178.1 28.6 2.7e-52 177.7 19.8 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 KZN84949.1 - 1.2e-28 99.0 0.7 2e-28 98.2 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN84949.1 - 5.4e-26 90.6 0.5 5.4e-26 90.6 0.4 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN84949.1 - 0.00022 22.1 0.2 0.00039 21.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN84949.1 - 0.0024 17.0 0.2 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1537 PF07005.6 KZN84949.1 - 0.05 13.2 0.5 0.05 13.2 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF1537 AlaDh_PNT_C PF01262.16 KZN84949.1 - 0.071 12.6 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1967 PF09269.6 KZN84949.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Peptidase_MA_2 PF13485.1 KZN84951.1 - 0.0014 18.6 0.1 0.0032 17.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily WD40 PF00400.27 KZN84952.1 - 2.7e-29 99.9 14.8 7.9e-10 38.2 0.0 9.6 10 0 0 10 10 10 6 WD domain, G-beta repeat HNH_2 PF13391.1 KZN84952.1 - 2.7e-11 43.0 0.2 6e-11 41.9 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease IKI3 PF04762.7 KZN84952.1 - 0.76 7.5 0.0 5.7 4.6 0.0 2.3 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.7 KZN84952.1 - 1.9 8.2 6.0 55 3.5 0.1 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SNF2_N PF00176.18 KZN84953.1 - 3.6e-71 239.4 2.6 7e-71 238.4 1.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KZN84953.1 - 1.6e-52 177.2 23.5 1.6e-52 177.2 16.3 4.3 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KZN84953.1 - 4.9e-17 61.5 0.0 1.6e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PuR_N PF09182.5 KZN84953.1 - 0.16 11.5 0.1 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DnaJ PF00226.26 KZN84954.1 - 1.5e-19 69.4 0.4 1.5e-19 69.4 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain MBF1 PF08523.5 KZN84954.1 - 0.079 12.9 6.9 0.19 11.7 4.8 1.7 1 0 0 1 1 1 0 Multiprotein bridging factor 1 DUF4200 PF13863.1 KZN84954.1 - 0.68 9.8 15.1 0.15 12.0 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) dCMP_cyt_deam_1 PF00383.17 KZN84955.1 - 2.2e-10 40.1 0.0 9.4e-10 38.0 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KZN84955.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Stn1 PF10451.4 KZN84956.1 - 1.7e-12 46.7 0.1 1.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KZN84956.1 - 1.8e-05 24.4 0.0 0.00061 19.6 0.0 2.3 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Ric8 PF10165.4 KZN84956.1 - 0.034 12.9 0.3 0.043 12.6 0.2 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn IMD PF08397.6 KZN84956.1 - 0.092 12.0 2.0 0.15 11.3 1.4 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain PIN_4 PF13638.1 KZN84956.1 - 0.14 12.2 0.6 0.23 11.5 0.4 1.3 1 0 0 1 1 1 0 PIN domain PhyH PF05721.8 KZN84956.1 - 0.16 12.0 1.1 0.31 11.0 0.8 1.5 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Stc1 PF12898.2 KZN84958.1 - 6.3e-22 77.4 14.7 8.8e-22 76.9 10.2 1.2 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.20 KZN84959.1 - 3.9e-59 199.9 0.0 6.3e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN84959.1 - 5.2e-31 107.6 0.0 2.6e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KZN84959.1 - 0.055 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_PH PF01138.16 KZN84960.1 - 5.7e-13 49.3 0.0 1.3e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KZN84960.1 - 0.042 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fmp27 PF10344.4 KZN84961.1 - 0.082 10.5 0.0 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 TMEM173 PF15009.1 KZN84961.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 Pneumo_att_G PF05539.6 KZN84961.1 - 1.8 7.8 4.2 2.6 7.3 2.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Cytochrom_C PF00034.16 KZN84962.1 - 6.2e-12 46.1 0.1 1.1e-11 45.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KZN84962.1 - 3.9e-08 33.3 3.6 2.8e-07 30.5 2.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KZN84962.1 - 0.00081 18.8 0.1 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.4 KZN84962.1 - 0.0056 15.9 0.3 0.0078 15.5 0.2 1.2 1 0 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Haem_bd PF14376.1 KZN84962.1 - 0.1 12.3 0.2 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Haem-binding domain Baculo_PEP_C PF04513.7 KZN84963.1 - 0.22 11.3 2.3 0.52 10.1 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.10 KZN84964.1 - 7.3e-46 155.3 1.6 1.2e-45 154.6 1.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KZN84964.1 - 1e-20 73.2 3.3 2.4e-20 72.0 2.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KZN84964.1 - 0.0072 16.2 0.4 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NUDIX PF00293.23 KZN84965.1 - 8.3e-18 64.3 0.2 1e-17 64.0 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.21 KZN84966.1 - 4.4e-30 104.1 0.0 6.8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KZN84966.1 - 1.8e-11 42.9 0.0 2.8e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.7 KZN84967.1 - 4e-30 104.7 0.5 5.7e-30 104.2 0.3 1.2 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.7 KZN84967.1 - 0.062 12.1 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF2232 PF09991.4 KZN84968.1 - 0.016 14.1 1.3 0.02 13.9 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TspO_MBR PF03073.10 KZN84968.1 - 0.035 13.6 0.3 0.041 13.3 0.2 1.1 1 0 0 1 1 1 0 TspO/MBR family DUF4345 PF14248.1 KZN84968.1 - 0.12 11.8 0.8 0.42 10.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) AA_permease_2 PF13520.1 KZN84969.1 - 1.1e-74 251.5 34.5 1.1e-74 251.5 23.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN84969.1 - 6.3e-15 54.4 32.7 1e-14 53.7 22.7 1.2 1 0 0 1 1 1 1 Amino acid permease GrpE PF01025.14 KZN84971.1 - 1.6e-41 141.6 7.1 2.5e-41 141.0 4.9 1.3 1 0 0 1 1 1 1 GrpE Phage_Gp23 PF10669.4 KZN84971.1 - 0.046 13.8 2.6 0.091 12.8 1.8 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Focal_AT PF03623.8 KZN84971.1 - 0.055 12.9 0.8 0.11 12.0 0.6 1.6 1 1 0 1 1 1 0 Focal adhesion targeting region tRNA-synt_2d PF01409.15 KZN84972.1 - 2.6e-48 164.3 0.1 4.9e-25 88.1 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KZN84972.1 - 1.5e-26 92.3 0.0 4.5e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 KZN84973.1 - 0.0012 18.4 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 KZN84974.1 - 1.7e-48 162.2 1.1 1e-17 63.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 KZN84975.1 - 7e-19 67.6 7.5 8e-19 67.4 5.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KZN84975.1 - 0.0038 16.6 1.4 0.0062 15.9 1.0 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain UCR_hinge PF02320.11 KZN84975.1 - 0.031 14.1 0.2 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein RRM_1 PF00076.17 KZN84976.1 - 7.9e-18 63.8 0.0 1.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN84976.1 - 8.9e-13 48.0 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN84976.1 - 8.1e-10 38.4 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KZN84976.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 KZN84976.1 - 0.056 13.2 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 KZN84977.1 - 2.2e-20 71.7 12.0 9.3e-05 22.1 0.6 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 KZN84977.1 - 2.7e-15 56.4 0.0 2.7e-15 56.4 0.0 3.9 4 1 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KZN84977.1 - 0.067 12.9 0.1 0.45 10.2 0.1 2.2 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Prp18 PF02840.10 KZN84977.1 - 0.31 10.8 0.9 0.85 9.4 0.1 2.1 2 1 0 2 2 2 0 Prp18 domain Pex14_N PF04695.8 KZN84978.1 - 1.9e-34 118.6 0.4 1.9e-34 118.6 0.3 2.5 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 KZN84978.1 - 4.2 5.4 8.3 3.6 5.6 4.7 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PAPA-1 PF04795.7 KZN84979.1 - 2.8e-29 101.6 5.2 2.8e-29 101.6 3.6 3.4 4 0 0 4 4 4 1 PAPA-1-like conserved region CD24 PF14984.1 KZN84979.1 - 0.17 11.7 1.4 0.32 10.8 1.0 1.4 1 0 0 1 1 1 0 CD24 protein Mus7 PF09462.5 KZN84981.1 - 1.5e-204 681.3 0.1 2.2e-204 680.8 0.1 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Glyco_hydro_71 PF03659.9 KZN84982.1 - 3.2e-119 397.8 8.0 3.4e-70 236.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KZN84982.1 - 0.47 10.1 3.0 1.2 8.8 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4434) AAA PF00004.24 KZN84983.1 - 7.1e-40 136.2 0.0 1.7e-37 128.5 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN84983.1 - 2.1e-05 24.5 0.3 0.005 16.8 0.0 3.4 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KZN84983.1 - 8.3e-05 22.7 0.4 0.0029 17.7 0.0 3.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KZN84983.1 - 0.00013 21.1 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KZN84983.1 - 0.0002 20.2 0.1 0.00061 18.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 KZN84983.1 - 0.00086 19.0 0.0 0.0028 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KZN84983.1 - 0.00097 19.9 0.2 0.0036 18.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN84983.1 - 0.0011 18.6 0.4 0.0038 16.9 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KZN84983.1 - 0.0013 18.6 0.0 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KZN84983.1 - 0.0045 16.9 0.1 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN84983.1 - 0.0048 16.3 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KZN84983.1 - 0.016 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KZN84983.1 - 0.02 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KZN84983.1 - 0.026 14.6 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SHQ1 PF04925.10 KZN84983.1 - 0.028 13.8 0.0 0.074 12.4 0.0 1.6 2 0 0 2 2 2 0 SHQ1 protein AAA_24 PF13479.1 KZN84983.1 - 0.048 13.2 0.2 0.14 11.6 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN84983.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1951 PF09188.5 KZN84983.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) PhoH PF02562.11 KZN84983.1 - 0.23 10.6 0.5 0.8 8.8 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein LIM_bind PF01803.11 KZN84984.1 - 4.5e-76 255.1 0.1 4.5e-76 255.1 0.1 3.8 3 1 1 4 4 4 1 LIM-domain binding protein cobW PF02492.14 KZN84985.1 - 3.3e-34 117.8 0.0 3.9e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KZN84985.1 - 4.7e-06 25.5 1.5 7.9e-05 21.5 1.1 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KZN84985.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KZN84985.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN84985.1 - 0.014 16.2 0.0 0.028 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KZN84985.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KZN84985.1 - 0.021 13.5 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 KZN84985.1 - 0.029 13.7 0.0 0.074 12.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KZN84985.1 - 0.073 12.7 0.0 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KZN84985.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PRK PF00485.13 KZN84985.1 - 0.087 12.3 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.18 KZN84985.1 - 0.092 12.1 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 KZN84985.1 - 0.11 12.4 0.1 0.39 10.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.9 KZN84985.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 KZN84985.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KZN84985.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin BING4CT PF08149.6 KZN84986.1 - 1.4e-39 133.4 0.0 1e-36 124.2 0.0 2.6 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 KZN84986.1 - 1.6e-05 24.6 0.0 0.0035 17.1 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4319 PF14203.1 KZN84986.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4319) Coatomer_WDAD PF04053.9 KZN84986.1 - 0.023 13.5 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region DUF663 PF04950.7 KZN84987.1 - 6.7e-96 320.7 0.2 1.1e-95 320.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KZN84987.1 - 2.7e-23 81.3 0.0 5.9e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.1 KZN84988.1 - 4.7e-116 386.8 11.2 5.3e-116 386.6 7.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KZN84988.1 - 1.4e-05 24.9 17.5 0.014 15.2 5.3 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN84988.1 - 0.00068 19.2 10.6 0.063 13.0 0.4 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KZN84988.1 - 0.0026 17.3 17.9 0.26 10.9 1.3 4.2 3 2 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 KZN84988.1 - 0.0039 16.7 20.4 0.17 11.5 0.3 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF2811 PF10929.3 KZN84988.1 - 0.0097 15.8 0.2 0.033 14.1 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2811) PhoU PF01895.14 KZN84988.1 - 0.013 15.9 4.7 1.3 9.5 0.2 3.2 2 1 1 3 3 3 0 PhoU domain TPR_6 PF13174.1 KZN84988.1 - 0.018 15.4 12.5 1.1 9.8 0.4 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN84988.1 - 0.027 14.2 0.9 0.027 14.2 0.6 6.0 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN84988.1 - 0.03 14.9 12.2 0.58 10.9 1.2 4.8 2 1 3 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 KZN84988.1 - 0.032 14.6 16.9 3.8 8.4 0.1 7.3 7 1 1 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat DFF40 PF09230.5 KZN84988.1 - 0.11 11.8 1.1 0.54 9.5 0.1 2.0 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa TPR_2 PF07719.12 KZN84988.1 - 0.65 10.0 24.9 0.83 9.7 0.5 7.5 4 3 3 8 8 8 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.10 KZN84989.1 - 4.4e-05 23.2 0.2 0.00089 19.0 0.2 2.2 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.7 KZN84990.1 - 3e-115 384.7 1.7 4e-115 384.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 KZN84990.1 - 2.5e-05 24.6 0.1 7.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 KZN84990.1 - 0.00015 21.5 0.4 0.00032 20.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN84990.1 - 0.0097 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KZN84990.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.15 KZN84990.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold APH PF01636.18 KZN84992.1 - 2e-13 50.6 0.0 3.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN84992.1 - 4.1e-05 23.2 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ADH_zinc_N_2 PF13602.1 KZN84993.1 - 1.1e-21 78.0 0.1 1.9e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN84993.1 - 1.5e-13 50.3 0.1 3.3e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN84993.1 - 9.5e-06 25.3 0.4 0.00021 21.0 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KZN84993.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fe_hyd_lg_C PF02906.9 KZN84993.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain DUF3335 PF11814.3 KZN84993.1 - 0.065 12.3 0.2 0.28 10.3 0.1 1.8 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_M20 PF01546.23 KZN84994.1 - 8.9e-18 64.4 0.2 1.4e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN84994.1 - 1.4e-10 40.8 0.0 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Alkyl_sulf_dimr PF14863.1 KZN84995.1 - 8.8e-58 194.5 0.0 1.4e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 KZN84995.1 - 4.9e-27 94.3 0.0 8.4e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 KZN84995.1 - 3.3e-23 82.3 0.0 5.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN84995.1 - 0.00023 20.7 0.0 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NatB_MDM20 PF09797.4 KZN84995.1 - 0.072 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Fungal_trans PF04082.13 KZN84996.1 - 2.6e-19 69.1 1.2 4.5e-19 68.3 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN84996.1 - 0.2 11.5 5.4 0.43 10.5 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Alkyl_sulf_dimr PF14863.1 KZN84997.1 - 1.5e-60 203.4 0.1 3.1e-60 202.4 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 KZN84997.1 - 1e-34 119.1 0.1 1.9e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 KZN84997.1 - 1.2e-24 87.0 0.7 2e-24 86.3 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_11 PF13414.1 KZN84997.1 - 3.6e-05 23.3 0.2 7.9e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KZN84997.1 - 4.9e-05 23.8 1.2 4.9e-05 23.8 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 KZN84997.1 - 0.00016 21.2 0.0 0.0004 19.9 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPR_19 PF14559.1 KZN84997.1 - 0.0019 18.4 0.2 0.0049 17.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Arylsulfotran_2 PF14269.1 KZN84998.1 - 2.7e-59 200.7 3.0 2e-58 197.9 2.7 1.8 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN84998.1 - 6.7e-16 57.8 3.2 2.3e-15 56.1 2.3 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.16 KZN84998.1 - 0.0078 15.7 0.3 9.9 5.9 0.1 3.4 2 0 0 2 2 2 2 PQQ enzyme repeat DUF1759 PF03564.10 KZN84999.1 - 0.076 12.8 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Amidase02_C PF12123.3 KZN84999.1 - 0.11 12.1 0.1 4.2 7.0 0.2 2.2 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DIOX_N PF14226.1 KZN85002.1 - 3.1e-13 50.2 0.0 6.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN85002.1 - 3e-05 24.2 0.0 0.0001 22.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KZN85003.1 - 4.7e-31 107.7 35.0 1.4e-30 106.1 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 KZN85003.1 - 0.0076 15.7 1.3 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Hexapep PF00132.19 KZN85004.1 - 2e-07 30.2 6.7 0.0053 16.2 2.3 3.5 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KZN85004.1 - 0.00072 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_114 PF03537.8 KZN85005.1 - 4.8e-27 93.5 0.4 4.8e-27 93.5 0.3 2.0 2 0 0 2 2 2 1 Glycoside-hydrolase family GH114 MIP-T3 PF10243.4 KZN85005.1 - 0.11 10.9 64.8 0.15 10.5 44.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Metallophos PF00149.23 KZN85006.1 - 2.3e-11 43.4 0.0 4.6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN85006.1 - 2.5e-09 37.1 0.1 4.2e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain C1_3 PF07649.7 KZN85007.1 - 0.057 13.4 2.4 0.27 11.2 1.7 2.1 1 1 0 1 1 1 0 C1-like domain Glyco_hydro_31 PF01055.21 KZN85008.1 - 1.9e-153 511.4 1.3 2.4e-153 511.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN85008.1 - 0.00046 19.9 0.1 0.0024 17.6 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_75 PF07335.6 KZN85009.1 - 1.5e-44 151.6 0.1 2.2e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ribosomal_L33 PF00471.15 KZN85010.1 - 0.0002 21.5 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L33 Rab5-bind PF09311.6 KZN85011.1 - 0.0043 16.9 30.8 0.0043 16.9 21.3 5.6 4 2 1 5 5 5 1 Rabaptin-like protein FlaC_arch PF05377.6 KZN85011.1 - 9.9 6.1 18.5 4.8 7.1 1.2 4.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pkinase PF00069.20 KZN85013.1 - 1.4e-61 207.9 0.0 1.9e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85013.1 - 3.3e-33 114.8 0.0 4.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN85013.1 - 3e-07 29.7 0.0 4.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN85013.1 - 0.0016 18.2 0.3 0.0016 18.2 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN85013.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 KZN85013.1 - 0.45 9.8 14.2 0.61 9.4 9.9 1.2 1 0 0 1 1 1 0 Vta1 like APH PF01636.18 KZN85014.1 - 1.8e-15 57.3 0.6 4.8e-15 55.9 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN85014.1 - 0.00098 18.3 0.0 0.51 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 KZN85014.1 - 0.025 13.9 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 KZN85014.1 - 0.052 13.1 0.1 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase Clr5 PF14420.1 KZN85016.1 - 0.00041 20.1 0.0 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 1 Clr5 domain PqqD PF05402.7 KZN85016.1 - 0.031 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Sugar_tr PF00083.19 KZN85017.1 - 1.3e-74 251.3 28.4 1.6e-74 251.1 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85017.1 - 1.5e-19 69.9 30.6 1.5e-19 69.9 21.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 KZN85018.1 - 5.9e-21 74.9 0.6 7.9e-21 74.4 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KZN85018.1 - 0.00017 20.5 0.0 0.00046 19.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KZN85018.1 - 0.00061 20.1 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KZN85018.1 - 0.0071 15.4 0.1 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KZN85018.1 - 0.078 11.9 0.3 0.28 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 TrkH PF02386.11 KZN85019.1 - 1e-106 356.5 6.2 4e-103 344.6 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein Epimerase PF01370.16 KZN85020.1 - 5.7e-11 42.2 0.0 8.1e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN85020.1 - 9.3e-10 38.8 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN85020.1 - 0.011 14.6 0.0 0.023 13.6 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KZN85020.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KZN85020.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cellulase PF00150.13 KZN85021.1 - 8.3e-14 51.4 2.1 8.3e-14 51.4 1.4 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 KZN85021.1 - 0.11 12.9 1.6 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HATPase_c PF02518.21 KZN85022.1 - 2.5e-18 65.8 0.1 1.4e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KZN85022.1 - 8.7e-14 51.2 0.4 2.7e-13 49.6 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KZN85022.1 - 5.9e-12 45.5 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PHY PF00360.15 KZN85022.1 - 1.7e-06 27.3 0.0 5.8e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Phytochrome region GAF PF01590.21 KZN85022.1 - 0.00015 21.9 0.0 0.0004 20.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 KZN85022.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_2 PF08446.6 KZN85022.1 - 0.029 14.8 0.0 0.078 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold SNF2_N PF00176.18 KZN85023.1 - 1.1e-74 250.9 0.0 2e-74 250.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN85023.1 - 3.3e-11 42.8 0.0 9.1e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 KZN85023.1 - 0.002 17.5 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 BUD22 PF09073.5 KZN85023.1 - 0.92 8.5 53.0 0.011 14.8 17.3 2.4 2 0 0 2 2 2 0 BUD22 TPP_enzyme_N PF02776.13 KZN85024.1 - 6.7e-41 139.6 0.3 6.4e-40 136.4 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KZN85024.1 - 1e-22 80.3 0.3 9.4e-22 77.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN85024.1 - 1.4e-15 57.2 0.0 3.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Peptidase_U35_2 PF14550.1 KZN85024.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative phage protease XkdF XFP_N PF09364.5 KZN85024.1 - 0.19 10.2 0.8 0.3 9.5 0.6 1.2 1 0 0 1 1 1 0 XFP N-terminal domain SIR2 PF02146.12 KZN85025.1 - 1e-38 132.8 0.0 5.3e-38 130.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family DUF4231 PF14015.1 KZN85025.1 - 0.1 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) APG12 PF04110.8 KZN85027.1 - 3.1e-29 100.9 0.0 7.3e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KZN85027.1 - 0.0045 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 KZN85028.1 - 6.7e-106 353.1 0.9 8.1e-106 352.9 0.6 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KZN85028.1 - 9.2e-08 31.5 0.5 2e-07 30.4 0.3 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Dfp1_Him1_M PF08630.5 KZN85029.1 - 5.7e-41 139.2 0.0 1.3e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KZN85029.1 - 1.1e-24 85.7 0.3 2.4e-24 84.7 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 KZN85029.1 - 0.033 14.0 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Peptidase_M24 PF00557.19 KZN85030.1 - 4.1e-50 170.2 0.0 5.9e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KZN85030.1 - 4.1e-35 120.0 0.0 7.2e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pyridox_ox_2 PF12900.2 KZN85031.1 - 6.9e-36 123.2 0.0 9.4e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ank_2 PF12796.2 KZN85032.1 - 2.6e-51 171.8 2.1 2e-15 56.8 0.0 8.8 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KZN85032.1 - 2e-35 118.8 20.0 4.2e-06 26.2 0.0 13.5 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.1 KZN85032.1 - 3.8e-34 115.9 5.7 8.9e-05 22.6 0.0 11.1 10 1 1 11 11 11 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN85032.1 - 1.5e-33 114.5 5.4 4.3e-06 27.0 0.0 11.5 11 0 0 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN85032.1 - 4.1e-24 82.2 11.0 0.0091 16.1 0.0 13.0 14 0 0 14 14 14 6 Ankyrin repeat LAMTOR PF15454.1 KZN85034.1 - 1.7e-23 82.6 0.1 2.6e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4045 PF13254.1 KZN85034.1 - 0.0013 18.1 2.1 0.0017 17.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) PolyA_pol_arg_C PF12626.2 KZN85034.1 - 0.082 12.5 0.1 1.5 8.4 0.1 2.2 1 1 1 2 2 2 0 Polymerase A arginine-rich C-terminus DUF2011 PF09428.5 KZN85035.1 - 6.2e-45 152.2 5.9 1e-44 151.5 4.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Tht1 PF04163.7 KZN85037.1 - 6.5e-06 24.8 10.3 7.9e-06 24.5 6.6 1.5 2 0 0 2 2 2 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.7 KZN85037.1 - 0.01 15.6 5.2 0.01 15.6 3.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LMP PF04778.7 KZN85037.1 - 0.38 10.4 8.4 0.69 9.6 0.2 2.9 3 0 0 3 3 3 0 LMP repeated region DUF3584 PF12128.3 KZN85037.1 - 2 5.6 23.8 3.3 4.9 16.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Trns_repr_metal PF02583.12 KZN85037.1 - 2 8.6 7.6 1.7 8.8 0.8 3.1 2 1 1 3 3 3 0 Metal-sensitive transcriptional repressor Folliculin PF11704.3 KZN85037.1 - 3.6 7.1 10.3 0.045 13.3 1.1 2.1 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport 5_nucleotid PF05761.9 KZN85037.1 - 6.9 5.0 8.3 8.4 4.7 0.3 2.2 2 0 0 2 2 2 0 5' nucleotidase family Ribosomal_L6 PF00347.18 KZN85039.1 - 3.5e-23 81.8 0.2 1.3e-11 44.7 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KZN85040.1 - 1.1e-50 172.5 1.5 3.6e-50 170.7 1.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 KZN85041.1 - 1.3e-25 89.6 0.0 3.5e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KZN85041.1 - 4.9e-09 36.0 0.4 1.1e-08 34.9 0.3 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 KZN85041.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 ENTH domain Dexa_ind PF15198.1 KZN85041.1 - 0.053 13.4 0.2 0.52 10.2 0.1 2.2 2 0 0 2 2 2 0 Dexamethasone-induced ABM PF03992.11 KZN85042.1 - 0.015 15.3 0.2 0.17 11.9 0.1 2.5 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Flavoprotein PF02441.14 KZN85043.1 - 7.8e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Abhydrolase_6 PF12697.2 KZN85043.1 - 1.5e-09 38.0 0.2 1.5e-09 38.0 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN85043.1 - 5e-09 36.0 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KZN85043.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF1391 PF07151.7 KZN85043.1 - 0.083 12.3 1.9 0.25 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) RNA_POL_M_15KD PF02150.11 KZN85044.1 - 0.0019 17.8 0.3 0.0048 16.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit HA2 PF04408.18 KZN85044.1 - 0.036 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Zn_Tnp_IS1595 PF12760.2 KZN85044.1 - 0.087 12.6 0.7 0.17 11.7 0.5 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF3039 PF11238.3 KZN85044.1 - 0.15 11.5 0.1 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) MFS_1 PF07690.11 KZN85045.1 - 5.2e-42 143.8 48.2 5.2e-42 143.8 33.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85045.1 - 1e-14 53.9 16.3 1e-14 53.9 11.3 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2140 PF09911.4 KZN85045.1 - 0.15 11.2 0.2 0.31 10.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3632 PF12311.3 KZN85047.1 - 4e-40 137.5 0.0 5.4e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Bradykinin PF06753.7 KZN85047.1 - 0.11 11.9 0.2 0.25 10.8 0.2 1.5 1 0 0 1 1 1 0 Bradykinin Antifungal_prot PF11402.3 KZN85048.1 - 2.6e-21 75.5 10.9 3.2e-21 75.2 7.6 1.1 1 0 0 1 1 1 1 Antifungal protein Macin PF14865.1 KZN85048.1 - 0.89 9.7 7.1 0.48 10.5 0.4 2.1 1 1 1 2 2 2 0 Macin Tannase PF07519.6 KZN85049.1 - 7.5e-115 384.3 0.8 1.4e-114 383.4 0.6 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KZN85049.1 - 0.00045 19.9 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN85049.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KZN85051.1 - 9.6e-07 27.8 37.6 9.6e-07 27.8 26.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FolB PF02152.13 KZN85052.1 - 5.8e-22 77.9 0.0 2.2e-16 60.0 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase PTR2 PF00854.16 KZN85054.1 - 8.9e-45 153.0 15.4 1.6e-30 106.1 0.5 2.4 3 0 0 3 3 3 2 POT family RseC_MucC PF04246.7 KZN85054.1 - 2.9 7.4 11.2 1.2 8.6 0.1 3.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Abhydrolase_3 PF07859.8 KZN85055.1 - 6.9e-37 127.0 0.0 9e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN85055.1 - 0.00039 19.2 1.1 0.0018 17.0 0.8 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KZN85055.1 - 0.0028 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN85055.1 - 0.0028 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KZN85055.1 - 0.02 14.1 0.1 0.03 13.5 0.1 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase Fungal_trans PF04082.13 KZN85056.1 - 4.2e-14 52.0 0.1 6.8e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpi16 PF04113.9 KZN85057.1 - 6.1e-253 839.9 0.0 7.1e-253 839.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 KZN85058.1 - 1.8e-71 240.6 2.4 2.2e-71 240.3 1.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 KZN85058.1 - 0.021 14.3 0.1 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.6 KZN85058.1 - 0.057 12.0 0.7 0.092 11.3 0.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Duo1 PF08651.5 KZN85058.1 - 0.092 12.3 0.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Prefoldin PF02996.12 KZN85058.1 - 0.19 11.3 1.1 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DegS PF05384.6 KZN85058.1 - 0.27 10.4 2.2 1.6 7.9 0.2 2.2 1 1 1 2 2 2 0 Sensor protein DegS Cep57_MT_bd PF06657.8 KZN85058.1 - 0.3 11.0 2.3 12 5.8 0.1 3.3 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TFIIS_M PF07500.9 KZN85059.1 - 2.1e-23 82.5 0.6 2.1e-23 82.5 0.4 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KZN85059.1 - 5.2e-20 72.1 0.0 1.1e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KZN85059.1 - 1.4e-10 40.6 13.0 2.5e-10 39.8 9.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KZN85059.1 - 0.0083 16.3 0.4 0.027 14.7 0.3 1.9 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 KZN85059.1 - 0.089 12.1 6.1 0.15 11.4 4.3 1.4 1 0 0 1 1 1 0 PHD-finger V_ATPase_I PF01496.14 KZN85060.1 - 2.2 6.0 3.6 2.7 5.7 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTV_NS2 PF04514.7 KZN85060.1 - 7.6 5.3 12.7 13 4.5 8.8 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hex_IIIa PF02455.11 KZN85060.1 - 8 5.0 8.7 11 4.5 6.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FF PF01846.14 KZN85061.1 - 4.7e-14 52.0 7.1 1.4e-10 40.9 0.1 3.5 3 0 0 3 3 3 2 FF domain WW PF00397.21 KZN85061.1 - 0.00065 19.5 1.6 0.00065 19.5 1.1 3.3 3 0 0 3 3 3 1 WW domain Proteasome PF00227.21 KZN85062.1 - 2.5e-61 206.2 0.2 3e-61 206.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KZN85062.1 - 3e-14 52.0 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4094 PF13334.1 KZN85063.1 - 0.046 14.1 0.5 0.058 13.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Not3 PF04065.10 KZN85063.1 - 0.077 12.2 1.9 0.1 11.8 1.2 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component NAD_binding_10 PF13460.1 KZN85065.1 - 5.5e-12 46.0 0.0 7.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN85065.1 - 1.2e-06 28.1 0.0 7.2e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN85065.1 - 0.0013 17.7 0.3 1.2 8.0 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KZN85065.1 - 0.0017 17.6 0.1 0.0036 16.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 KZN85065.1 - 0.0046 15.4 0.0 0.0064 14.9 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.19 KZN85065.1 - 0.0046 17.2 0.1 0.035 14.4 0.0 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.8 KZN85065.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) YTH PF04146.10 KZN85065.1 - 0.099 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 YT521-B-like domain 3Beta_HSD PF01073.14 KZN85065.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ank PF00023.25 KZN85066.1 - 8.1e-28 94.8 2.4 1.4e-06 27.8 0.2 7.2 7 1 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KZN85066.1 - 8.4e-27 93.3 0.0 2.9e-11 43.5 0.0 3.9 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN85066.1 - 3.6e-18 63.8 1.4 5.8e-05 22.9 0.1 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 KZN85066.1 - 2.7e-14 53.2 1.6 0.0012 19.3 0.0 6.4 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN85066.1 - 9.1e-12 44.8 1.5 0.019 15.2 0.0 6.6 8 0 0 8 8 8 2 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN85066.1 - 0.018 14.7 0.4 0.035 13.8 0.3 1.5 1 0 0 1 1 1 0 F-box-like Acyl-CoA_dh_1 PF00441.19 KZN85067.1 - 1.8e-33 115.7 0.5 3.3e-33 114.8 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN85067.1 - 1.3e-20 72.6 0.8 2.3e-20 71.8 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KZN85067.1 - 4e-14 53.1 0.2 1.8e-13 51.0 0.0 2.3 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KZN85067.1 - 3.6e-06 27.2 1.3 4.2e-06 27.0 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain RicinB_lectin_2 PF14200.1 KZN85069.1 - 5.7e-09 36.2 0.6 5.4e-07 29.9 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KZN85069.1 - 1.5e-05 25.0 0.1 2.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Antirestrict PF03230.8 KZN85069.1 - 0.46 10.5 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Antirestriction protein FB_lectin PF07367.6 KZN85070.1 - 4.4e-50 168.9 0.2 5.1e-50 168.7 0.1 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin zf-C2H2_4 PF13894.1 KZN85071.1 - 2.3e-08 33.7 27.1 0.35 11.2 0.3 7.7 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN85071.1 - 0.0015 18.7 39.7 0.81 10.1 0.2 8.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-FCS PF06467.9 KZN85071.1 - 0.012 15.2 8.4 0.038 13.6 0.1 4.3 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.1 KZN85071.1 - 0.054 13.4 10.7 2.5 8.1 1.0 4.3 3 1 0 3 3 3 0 C2H2-type zinc finger zf-CHCC PF10276.4 KZN85071.1 - 3 7.7 15.1 4.4 7.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain FAD_binding_1 PF00667.15 KZN85072.1 - 9.2e-60 201.7 0.0 1.6e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KZN85072.1 - 3.2e-11 43.7 0.0 1.1e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KZN85072.1 - 1.5e-08 34.7 0.3 3.4e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KZN85072.1 - 0.0015 18.4 0.1 0.0071 16.2 0.1 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain FtsJ PF01728.14 KZN85073.1 - 7.4e-63 211.7 0.0 9.6e-63 211.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 KZN85074.1 - 2.6e-44 150.6 0.1 5.7e-44 149.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN85074.1 - 2.2e-22 78.7 0.1 1.3e-21 76.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KZN85074.1 - 0.0013 17.5 0.0 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KZN85074.1 - 0.02 15.0 0.2 0.066 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Sec62 PF03839.11 KZN85074.1 - 4.8 6.5 8.8 13 5.0 6.1 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1688 PF07958.6 KZN85075.1 - 4.1e-167 555.9 0.0 4.6e-167 555.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 4HBT PF03061.17 KZN85077.1 - 2e-08 34.2 0.0 4.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily HECT PF00632.20 KZN85079.1 - 4.6e-80 269.1 0.0 7.3e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 KZN85079.1 - 0.00029 20.6 0.5 0.072 13.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 KZN85079.1 - 0.053 13.3 5.5 2.4 8.1 0.0 5.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KZN85079.1 - 0.084 12.2 0.2 1.9 7.7 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.1 KZN85079.1 - 0.086 13.3 0.4 2.4 8.7 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat OAD_beta PF03977.8 KZN85079.1 - 0.24 10.1 0.1 0.38 9.4 0.1 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit CTP_transf_2 PF01467.21 KZN85080.1 - 1.7e-29 102.9 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 KZN85080.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 1 1 2 2 2 0 Mnd1 family SIS PF01380.17 KZN85081.1 - 6.5e-14 51.6 0.0 1.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KZN85081.1 - 1e-05 25.2 0.0 0.003 17.2 0.0 2.3 1 1 1 2 2 2 2 SIS domain Ubie_methyltran PF01209.13 KZN85082.1 - 3.3e-81 271.8 0.0 4.5e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KZN85082.1 - 1.1e-13 51.4 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85082.1 - 2e-13 50.1 0.0 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN85082.1 - 1.6e-11 44.5 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN85082.1 - 7.1e-11 42.3 0.0 4.5e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN85082.1 - 2.2e-09 37.2 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN85082.1 - 7e-07 29.8 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN85082.1 - 6.5e-05 22.9 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KZN85082.1 - 0.0059 16.2 0.0 0.044 13.4 0.0 2.2 2 1 0 2 2 2 1 Hypothetical methyltransferase DUF3649 PF12365.3 KZN85082.1 - 0.83 9.2 3.0 0.59 9.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) AA_permease PF00324.16 KZN85083.1 - 6.2e-103 344.6 43.5 7e-103 344.5 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN85083.1 - 1.8e-33 115.7 47.5 2.1e-33 115.5 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KZN85083.1 - 3.1 7.4 4.6 1.5 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) Fungal_trans PF04082.13 KZN85084.1 - 1.9e-15 56.4 0.0 2.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85084.1 - 4.5e-05 23.2 8.9 8.1e-05 22.4 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KZN85085.1 - 2.3e-84 283.5 14.1 2.7e-84 283.3 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85085.1 - 2.9e-30 105.1 42.5 5e-24 84.6 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN85085.1 - 0.0031 15.7 0.5 0.0031 15.7 0.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UPF0075 PF03702.9 KZN85086.1 - 2.1e-75 253.9 0.0 2.6e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 KZN85086.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family NAGidase PF07555.8 KZN85087.1 - 6.1e-103 343.9 1.3 6.1e-103 343.9 0.9 1.5 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 KZN85087.1 - 3.7e-23 82.3 0.1 8.3e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 KZN85087.1 - 0.0017 18.3 0.2 0.0037 17.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DUF4455 PF14643.1 KZN85087.1 - 0.024 13.3 0.1 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Amino_oxidase PF01593.19 KZN85089.1 - 1.7e-64 218.5 0.7 4e-64 217.3 0.5 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN85089.1 - 1.9e-09 37.3 0.2 6.8e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN85089.1 - 1.2e-06 28.7 1.7 0.00034 20.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN85089.1 - 9.1e-06 24.7 0.0 0.085 11.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KZN85089.1 - 0.00096 18.2 0.2 0.013 14.5 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 KZN85089.1 - 0.0025 16.9 0.6 0.025 13.6 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN85089.1 - 0.0042 17.4 0.4 0.16 12.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN85089.1 - 0.013 14.3 0.3 0.034 13.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KZN85089.1 - 0.014 15.2 0.1 0.046 13.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN85089.1 - 0.019 13.8 0.0 0.071 11.9 0.1 1.8 2 1 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 KZN85089.1 - 0.028 13.9 0.1 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KZN85089.1 - 0.031 12.7 0.4 0.29 9.5 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KZN85089.1 - 0.039 13.6 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KZN85089.1 - 0.049 12.7 0.2 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KZN85089.1 - 0.054 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans_2 PF11951.3 KZN85090.1 - 0.0008 18.1 3.1 0.0022 16.6 2.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Y_phosphatase3 PF13350.1 KZN85091.1 - 2.4e-39 135.1 0.0 3.3e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KZN85091.1 - 1.7e-06 28.0 0.0 6.7e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KZN85091.1 - 5.3e-06 25.9 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KZN85091.1 - 0.0035 17.3 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 KZN85091.1 - 0.0041 16.5 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.9 KZN85091.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain NUDIX PF00293.23 KZN85092.1 - 6.2e-08 32.3 0.0 7.7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KZN85092.1 - 0.15 11.5 0.0 7.8 5.9 0.0 2.1 2 0 0 2 2 2 0 NUDIX domain E1_dh PF00676.15 KZN85093.1 - 1.9e-88 296.0 0.0 2.3e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KZN85093.1 - 1.3e-05 24.8 0.1 0.00027 20.5 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 KZN85093.1 - 0.035 12.6 0.0 0.063 11.8 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain SGS PF05002.10 KZN85093.1 - 0.037 13.7 1.7 3 7.6 0.7 2.7 2 1 0 2 2 2 0 SGS domain DXP_synthase_N PF13292.1 KZN85093.1 - 0.057 12.3 0.0 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Spherulin4 PF12138.3 KZN85094.1 - 9.2e-45 153.0 0.6 1e-44 152.8 0.4 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 zf-RING_4 PF14570.1 KZN85095.1 - 5.9e-19 67.3 13.7 1.1e-18 66.4 9.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KZN85095.1 - 5.5e-05 22.7 6.0 9.9e-05 21.9 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KZN85095.1 - 7.2e-05 22.3 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85095.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 KZN85095.1 - 0.006 16.3 4.8 0.011 15.4 3.4 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 KZN85095.1 - 0.006 15.8 2.0 0.006 15.8 1.4 2.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 KZN85095.1 - 0.091 12.4 12.2 0.18 11.4 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN85095.1 - 0.5 10.4 11.1 0.93 9.5 7.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 KZN85096.1 - 2.6e-36 123.9 0.0 3.8e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BUD22 PF09073.5 KZN85097.1 - 1.9e-93 313.8 14.6 2.4e-93 313.5 10.1 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.13 KZN85098.1 - 4.5e-26 91.2 0.0 8e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85098.1 - 1.8e-05 24.5 10.8 4.1e-05 23.4 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavi_NS5 PF00972.15 KZN85098.1 - 0.097 10.5 0.0 0.14 9.9 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase Shikimate_DH PF01488.15 KZN85099.1 - 0.00018 21.6 0.0 0.00066 19.7 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pro_dh PF01619.13 KZN85100.1 - 2.4e-35 122.0 0.2 3.5e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 KZN85101.1 - 1.5e-106 356.5 0.1 1.8e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.19 KZN85102.1 - 1.2e-33 116.1 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.14 KZN85103.1 - 4.9e-58 196.6 0.0 7e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KZN85103.1 - 1.4e-36 125.8 0.2 2.8e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KZN85103.1 - 1.7e-05 24.5 0.1 2.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN85103.1 - 0.00073 18.7 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN85103.1 - 0.0014 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KZN85103.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KZN85103.1 - 0.041 13.2 0.1 0.088 12.1 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 KZN85103.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PNP_UDP_1 PF01048.15 KZN85104.1 - 4.5e-39 133.8 0.2 5.6e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF747 PF05346.6 KZN85105.1 - 2.1e-128 428.0 2.1 2.8e-128 427.6 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family OSTbeta PF15048.1 KZN85105.1 - 0.036 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein adh_short PF00106.20 KZN85107.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN85107.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 KR domain PBP_like PF12727.2 KZN85108.1 - 0.099 11.5 0.1 0.18 10.7 0.1 1.4 1 1 0 1 1 1 0 PBP superfamily domain RNHCP PF12647.2 KZN85109.1 - 0.048 13.4 0.2 0.089 12.6 0.2 1.5 1 0 0 1 1 1 0 RNHCP domain p450 PF00067.17 KZN85110.1 - 9.5e-77 258.4 0.0 1.3e-76 258.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KZN85111.1 - 1.1e-06 28.3 5.8 2.1e-06 27.5 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 KZN85112.1 - 5.1e-13 49.0 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN85112.1 - 8e-13 48.1 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN85112.1 - 2.4e-09 37.2 0.0 4.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN85112.1 - 1.8e-06 27.8 0.0 3.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN85112.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN85112.1 - 0.0095 16.4 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 KZN85113.1 - 3.4e-49 167.2 0.0 4.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KZN85113.1 - 1.4e-23 82.8 0.0 3.2e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 KZN85114.1 - 1e-192 640.2 0.1 1.2e-192 640.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ribosomal_L11 PF00298.14 KZN85115.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Glyoxalase PF00903.20 KZN85116.1 - 3.5e-20 72.2 0.5 2.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KZN85116.1 - 7.7e-14 51.6 0.2 9.1e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KZN85116.1 - 1.6e-08 35.0 0.0 0.0032 18.0 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KZN85116.1 - 4.1e-07 30.0 0.2 1.2e-05 25.3 0.1 2.4 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KZN85116.1 - 2.3e-06 27.6 0.3 0.1 12.4 0.1 3.5 3 1 0 3 3 3 2 Glyoxalase-like domain zf-CHY PF05495.7 KZN85117.1 - 3.5e-18 65.5 15.4 3.5e-18 65.5 10.7 3.6 3 0 0 3 3 3 2 CHY zinc finger zf-CCCH PF00642.19 KZN85117.1 - 0.062 12.9 6.4 0.031 13.9 1.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3295 PF11702.3 KZN85118.1 - 2.1e-189 630.7 27.0 2.7e-189 630.3 18.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KZN85118.1 - 1.5e-12 46.8 1.6 4e-12 45.4 1.1 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Cpn60_TCP1 PF00118.19 KZN85120.1 - 2.5e-144 481.5 2.3 2.9e-144 481.3 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 KZN85120.1 - 0.15 11.9 2.0 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Chromo PF00385.19 KZN85121.1 - 7.9e-10 38.2 1.3 7.9e-10 38.2 0.9 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KZN85121.1 - 2e-09 37.1 0.8 2.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain BSP_II PF05432.6 KZN85121.1 - 0.89 8.7 16.9 1.8 7.7 11.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Prothymosin PF03247.9 KZN85121.1 - 2.7 8.2 28.1 0.34 11.0 15.6 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family FAM176 PF14851.1 KZN85121.1 - 7.9 6.1 10.5 0.67 9.6 2.3 2.2 2 0 0 2 2 2 0 FAM176 family Rap1_C PF11626.3 KZN85122.1 - 8.7e-23 80.0 0.0 1.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KZN85122.1 - 8.4e-16 57.5 0.5 1.6e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KZN85122.1 - 0.0013 19.2 0.1 0.008 16.7 0.0 2.2 2 0 0 2 2 2 1 Rap1, DNA-binding zf-DHHC PF01529.15 KZN85123.1 - 1.9e-27 95.8 10.0 2.3e-27 95.4 6.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase stn_TNFRSF12A PF12191.3 KZN85123.1 - 0.055 13.4 8.4 0.049 13.6 4.1 2.0 1 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Atx10homo_assoc PF09759.4 KZN85124.1 - 4.2e-30 103.4 0.3 1.8e-29 101.4 0.1 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF2360 PF10152.4 KZN85124.1 - 0.068 13.4 0.7 0.93 9.7 0.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RYDR_ITPR PF01365.16 KZN85124.1 - 0.11 11.7 0.7 0.39 9.8 0.2 2.0 2 0 0 2 2 2 0 RIH domain Bap31 PF05529.7 KZN85125.1 - 0.041 13.3 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ost4 PF10215.4 KZN85125.1 - 8.1 6.0 6.2 13 5.3 4.3 1.3 1 0 0 1 1 1 0 Oligosaccaryltransferase zf-RING_2 PF13639.1 KZN85126.1 - 1.9e-08 34.0 2.8 2.8e-08 33.4 1.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN85126.1 - 2.9e-06 27.3 0.7 6.7e-06 26.1 0.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN85126.1 - 0.00075 19.2 0.6 0.0012 18.6 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KZN85126.1 - 0.0012 18.8 2.2 0.0018 18.2 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KZN85126.1 - 0.0041 17.0 0.3 0.01 15.8 0.2 1.7 1 0 0 1 1 1 1 zinc-finger zf-C3HC4 PF00097.20 KZN85126.1 - 0.021 14.4 0.9 0.036 13.7 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN85126.1 - 0.13 11.9 1.4 0.47 10.1 1.0 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pyridox_oxidase PF01243.15 KZN85127.1 - 6.8e-09 35.6 0.0 0.00014 21.7 0.0 2.8 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 KZN85127.1 - 3.3e-06 27.1 0.0 4.2e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain TMEM192 PF14802.1 KZN85128.1 - 0.84 8.4 4.6 0.19 10.5 0.5 1.7 1 1 1 2 2 2 0 TMEM192 family NTP_transferase PF00483.18 KZN85129.1 - 4e-29 101.6 0.0 5.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KZN85129.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KZN85129.1 - 4.4e-08 32.2 6.2 8.2e-07 28.2 0.1 3.7 2 1 1 3 3 3 1 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 KZN85129.1 - 0.0027 17.2 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.7 KZN85129.1 - 0.027 13.0 0.0 0.46 8.9 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase Glycos_transf_2 PF00535.21 KZN85129.1 - 0.042 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KZN85129.1 - 0.13 11.9 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 APH PF01636.18 KZN85130.1 - 0.0098 15.6 0.1 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dynamin_N PF00350.18 KZN85133.1 - 1.4e-24 86.7 0.0 5.5e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KZN85133.1 - 2.7e-16 59.2 0.2 6.3e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KZN85133.1 - 7.3e-05 22.7 0.0 0.0011 18.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KZN85133.1 - 0.0016 18.2 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 KZN85133.1 - 0.0026 18.2 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein tRNA-synt_2 PF00152.15 KZN85134.1 - 5.5e-88 294.9 0.9 9.4e-88 294.1 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN85134.1 - 3.3e-13 49.2 0.1 9e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KZN85134.1 - 3.8e-06 26.2 0.0 0.0065 15.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Gb3_synth PF04572.7 KZN85134.1 - 0.0037 16.9 0.0 0.024 14.3 0.0 2.2 1 1 1 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region UCR_Fe-S_N PF10399.4 KZN85134.1 - 0.045 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal POX PF07526.6 KZN85134.1 - 0.32 11.2 5.4 0.74 10.0 3.7 1.5 1 0 0 1 1 1 0 Associated with HOX Peptidase_S49_N PF08496.5 KZN85134.1 - 5.4 6.7 6.4 12 5.6 4.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-C3HC4_2 PF13923.1 KZN85135.1 - 0.11 12.4 3.9 0.23 11.5 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 KZN85135.1 - 0.14 12.1 5.3 0.24 11.3 3.7 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_3 PF13920.1 KZN85135.1 - 0.85 9.3 7.7 0.46 10.1 3.8 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 KZN85135.1 - 2.8 6.0 8.0 3.5 5.7 5.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C4H2 PF10146.4 KZN85135.1 - 6 6.8 11.9 12 5.8 8.3 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein COX15-CtaA PF02628.10 KZN85136.1 - 2.1e-97 325.6 8.0 2.5e-97 325.3 5.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein zf-C3HC PF07967.8 KZN85137.1 - 3.6e-39 133.5 0.1 1.1e-35 122.2 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KZN85137.1 - 7.8e-33 112.1 1.5 2.6e-30 104.1 0.0 3.0 3 0 0 3 3 3 2 Rsm1-like DUF1759 PF03564.10 KZN85137.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Pox_MCEL PF03291.11 KZN85138.1 - 1.5e-63 214.7 0.0 1.4e-31 109.6 0.0 3.8 3 1 0 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 KZN85138.1 - 2e-07 31.3 0.0 1.5e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85138.1 - 9.7e-07 29.2 0.0 0.014 15.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KZN85138.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN85138.1 - 2.3e-05 24.9 0.0 5.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85138.1 - 2.4e-05 23.9 0.0 0.0055 16.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KZN85138.1 - 0.00088 19.5 0.0 0.0047 17.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KZN85138.1 - 0.01 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-Nse PF11789.3 KZN85139.1 - 3.2e-22 77.7 1.2 6.1e-22 76.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KZN85139.1 - 3.8e-05 23.4 0.3 6.3e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KZN85139.1 - 0.0028 17.3 0.2 0.011 15.4 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 KZN85139.1 - 0.041 13.3 3.8 0.24 10.9 2.6 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger MFS_1 PF07690.11 KZN85140.1 - 5.5e-11 41.7 29.6 1.1e-10 40.8 20.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN85140.1 - 5.1e-09 35.8 5.6 5.1e-09 35.8 3.9 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.22 KZN85141.1 - 7.7e-57 189.0 3.4 4.5e-20 71.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEPCK_ATP PF01293.15 KZN85143.1 - 1.9e-214 712.5 0.0 2.2e-214 712.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 KZN85143.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN85143.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DZR PF12773.2 KZN85147.1 - 0.0069 16.1 5.8 0.0078 16.0 4.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KZN85147.1 - 0.023 14.1 7.4 0.026 14.0 4.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.1 KZN85147.1 - 0.13 11.9 3.7 0.21 11.3 2.6 1.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 KZN85147.1 - 0.14 11.4 12.3 0.41 9.9 7.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 KZN85147.1 - 0.31 10.5 3.7 4.3 6.9 0.1 2.1 1 1 1 2 2 2 0 A2L zinc ribbon domain Fer4_3 PF12798.2 KZN85147.1 - 0.86 10.3 9.5 0.28 11.8 1.2 2.3 2 1 0 2 2 2 0 4Fe-4S binding domain zinc_ribbon_5 PF13719.1 KZN85147.1 - 1 9.0 4.0 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Fer4 PF00037.22 KZN85147.1 - 1.3 8.7 9.2 0.6 9.7 2.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain zf-NADH-PPase PF09297.6 KZN85147.1 - 1.4 8.4 9.5 69 3.0 6.6 2.2 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-HIT PF04438.11 KZN85147.1 - 2.6 7.7 6.2 5.3 6.7 0.1 2.2 2 1 0 2 2 2 0 HIT zinc finger zf-tcix PF14952.1 KZN85147.1 - 3.8 6.9 12.9 1.5 8.2 2.9 2.1 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Fer4_6 PF12837.2 KZN85147.1 - 4.1 7.4 6.7 5.6 7.0 1.0 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain zinc_ribbon_4 PF13717.1 KZN85147.1 - 4.7 6.9 5.8 3.6 7.3 0.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.15 KZN85147.1 - 5.8 6.8 6.5 1.9 8.4 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin Zn-ribbon_8 PF09723.5 KZN85147.1 - 6.9 6.7 9.5 0.87 9.5 0.6 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KZN85147.1 - 8.6 6.2 8.1 14 5.5 3.8 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PEX11 PF05648.9 KZN85148.1 - 6.5e-78 261.0 0.1 7.3e-78 260.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) COX14 PF14880.1 KZN85148.1 - 0.0093 15.5 0.3 0.06 12.9 0.0 2.5 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Spore_YhaL PF14147.1 KZN85148.1 - 0.093 12.1 0.2 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL Sugar_tr PF00083.19 KZN85149.1 - 9.8e-27 93.6 34.6 1.6e-17 63.2 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KZN85149.1 - 5.2e-16 58.3 41.7 1.4e-11 43.7 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPN7 PF10602.4 KZN85150.1 - 8.2e-53 178.3 0.2 1.3e-52 177.7 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KZN85150.1 - 5.4e-15 55.5 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.16 KZN85151.1 - 3.3e-39 134.8 0.0 5.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Exo_endo_phos PF03372.18 KZN85152.1 - 2.6e-11 43.9 0.1 3.6e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_6 PF12697.2 KZN85153.1 - 2.5e-23 83.1 2.0 2.5e-23 83.1 1.4 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN85153.1 - 8e-15 54.8 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN85153.1 - 6e-08 32.5 0.1 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KZN85153.1 - 0.00088 19.5 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1612 PF07756.7 KZN85153.1 - 0.021 14.9 0.2 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Hydrolase_4 PF12146.3 KZN85153.1 - 0.021 14.6 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KZN85153.1 - 0.063 12.7 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Copper-fist PF00649.13 KZN85154.1 - 4.4e-21 73.7 3.2 4.4e-21 73.7 2.2 2.9 2 1 1 3 3 3 1 Copper fist DNA binding domain Zn_clus PF00172.13 KZN85155.1 - 2.4e-10 40.1 8.2 3.8e-10 39.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SspK PF08176.7 KZN85157.1 - 0.086 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Small acid-soluble spore protein K family RPE65 PF03055.10 KZN85158.1 - 6.6e-121 404.2 0.0 7.4e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.13 KZN85159.1 - 7.7e-17 61.0 0.1 1.2e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85159.1 - 5.3e-08 32.6 6.6 5.3e-08 32.6 4.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrgI PF12666.2 KZN85161.1 - 1.8 8.7 8.8 1.4 9.1 0.1 3.2 3 0 0 3 3 3 0 PrgI family protein ArfGap PF01412.13 KZN85162.1 - 2.8e-40 136.7 0.2 4.1e-40 136.2 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 KZN85163.1 - 8.3e-50 167.6 0.1 1.1e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 SelR domain Auxin_repressed PF05564.7 KZN85163.1 - 0.094 13.3 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein DZR PF12773.2 KZN85163.1 - 0.29 10.9 3.2 11 5.9 2.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon Smr PF01713.16 KZN85164.1 - 2.6e-07 30.7 0.6 7.3e-07 29.3 0.4 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 KZN85164.1 - 0.016 14.6 0.7 0.03 13.8 0.1 1.8 2 0 0 2 2 2 0 CUE domain Zds_C PF08632.5 KZN85165.1 - 3.4e-31 106.4 1.3 7.4e-31 105.3 0.9 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF500 PF04366.7 KZN85166.1 - 7.3e-44 148.2 0.9 1.4e-43 147.2 0.4 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KZN85166.1 - 5.4e-13 48.1 0.2 2e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KZN85166.1 - 1.3e-11 43.7 0.1 3.2e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KZN85166.1 - 3e-10 39.5 0.0 3e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Miro PF08477.8 KZN85167.1 - 2.6e-38 131.1 0.0 5.3e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KZN85167.1 - 2.4e-35 120.1 0.0 4.3e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KZN85167.1 - 2.1e-31 107.0 0.0 3.6e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KZN85167.1 - 2.1e-24 85.7 0.0 1.9e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KZN85167.1 - 1.2e-10 41.4 0.0 0.00064 19.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 KZN85167.1 - 1.2e-07 30.4 1.1 0.0013 17.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KZN85167.1 - 4.2e-07 30.0 0.3 0.00064 19.8 0.1 3.0 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN85167.1 - 5.6e-07 28.9 1.6 0.0012 18.4 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_29 PF13555.1 KZN85167.1 - 1.9e-05 24.0 0.2 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN85167.1 - 2.9e-05 24.2 0.5 1.1 9.4 0.0 3.2 2 1 1 3 3 3 2 AAA domain EF-hand_8 PF13833.1 KZN85167.1 - 3e-05 23.5 0.8 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 KZN85167.1 - 3.8e-05 23.7 3.4 0.059 13.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 KZN85167.1 - 9.8e-05 22.2 0.4 0.37 10.6 0.2 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KZN85167.1 - 0.00019 20.8 0.1 0.6 9.5 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 KZN85167.1 - 0.00022 21.2 0.1 0.086 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 KZN85167.1 - 0.00022 20.3 2.6 0.012 14.8 0.2 2.7 2 0 0 2 2 2 1 EF hand FtsK_SpoIIIE PF01580.13 KZN85167.1 - 0.001 18.6 0.0 0.39 10.1 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 KZN85167.1 - 0.0011 18.6 0.1 0.25 11.0 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KZN85167.1 - 0.0015 18.0 0.2 0.036 13.5 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KZN85167.1 - 0.0016 17.8 0.0 2 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN85167.1 - 0.0018 18.5 0.1 2.8 8.2 0.0 2.9 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN85167.1 - 0.0044 17.1 0.0 0.85 9.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 KZN85167.1 - 0.0049 16.3 0.0 0.83 9.0 0.0 2.6 3 0 0 3 3 2 1 AAA-like domain AAA_33 PF13671.1 KZN85167.1 - 0.0051 16.6 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN85167.1 - 0.0055 16.3 0.4 3.7 7.1 0.0 2.7 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KZN85167.1 - 0.0056 16.9 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 KZN85167.1 - 0.0084 15.7 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KZN85167.1 - 0.011 16.5 0.0 8 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KZN85167.1 - 0.016 14.6 0.8 1.1 8.6 0.1 3.7 4 1 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KZN85167.1 - 0.02 14.1 0.1 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF815 PF05673.8 KZN85167.1 - 0.039 12.8 0.3 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KZN85167.1 - 0.051 13.3 0.7 24 4.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Septin PF00735.13 KZN85167.1 - 0.052 12.5 0.0 0.84 8.5 0.0 2.2 2 0 0 2 2 2 0 Septin SMC_N PF02463.14 KZN85167.1 - 0.067 12.4 0.4 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IIGP PF05049.8 KZN85167.1 - 0.083 11.6 0.4 1.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) EF-hand_10 PF14788.1 KZN85167.1 - 0.11 12.2 0.6 0.57 9.8 0.1 2.2 2 0 0 2 2 2 0 EF hand DUF3201 PF11447.3 KZN85167.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) AAA PF00004.24 KZN85167.1 - 0.13 12.4 1.2 14 5.8 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KZN85167.1 - 0.19 12.0 0.2 32 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KZN85167.1 - 0.19 10.2 0.1 14 4.1 0.0 2.3 2 1 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 KZN85167.1 - 0.2 11.1 1.7 29 4.0 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KZN85167.1 - 0.21 10.3 0.4 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 ArgK protein WD40 PF00400.27 KZN85168.1 - 7.6e-19 66.8 12.2 4e-06 26.4 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 KZN85168.1 - 1.5e-05 23.0 0.0 0.00046 18.1 0.0 2.0 1 1 1 2 2 2 2 IKI3 family eIF2A PF08662.6 KZN85168.1 - 0.0074 16.0 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KZN85168.1 - 0.0091 14.3 0.0 0.022 13.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Pkinase PF00069.20 KZN85169.1 - 1.2e-26 93.3 0.0 1.4e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85169.1 - 2.9e-11 42.9 0.0 1.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GPI-anchored PF10342.4 KZN85170.1 - 4.6e-18 65.4 1.3 4.6e-18 65.4 0.9 4.8 2 1 3 5 5 5 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AAA_10 PF12846.2 KZN85171.1 - 1.7e-08 34.2 0.0 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KZN85171.1 - 0.0024 18.0 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zot PF05707.7 KZN85171.1 - 0.0039 16.6 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 KZN85171.1 - 0.0057 16.8 0.1 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KZN85171.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KZN85171.1 - 0.04 12.5 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.7 KZN85171.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Ank_2 PF12796.2 KZN85172.1 - 1.4e-23 83.0 0.0 4.6e-13 49.3 0.0 3.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN85172.1 - 8.6e-18 64.3 0.4 2.6e-07 30.9 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN85172.1 - 3.2e-15 55.7 0.2 0.0038 17.4 0.0 6.5 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 KZN85172.1 - 6.3e-14 50.9 3.8 0.016 15.0 0.0 6.3 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KZN85172.1 - 3.2e-10 39.2 0.3 0.052 13.7 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat F-box-like PF12937.2 KZN85172.1 - 0.031 13.9 0.2 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like Ribonuc_L-PSP PF01042.16 KZN85173.1 - 5.4e-10 39.0 0.2 3.7e-08 33.1 0.0 2.3 2 1 0 2 2 2 1 Endoribonuclease L-PSP Zn_clus PF00172.13 KZN85174.1 - 2.2e-08 33.8 14.7 4.4e-08 32.8 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KZN85175.1 - 5.3e-20 71.8 1.7 7.6e-20 71.3 1.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3112 PF11309.3 KZN85175.1 - 0.039 13.7 7.1 2.5 7.8 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) CATSPERB PF15149.1 KZN85175.1 - 0.16 10.1 0.7 0.24 9.5 0.1 1.5 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit beta protein family DAO PF01266.19 KZN85176.1 - 1.3e-53 182.1 0.0 1.6e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN85176.1 - 7.3e-07 29.1 0.0 2.4e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN85176.1 - 0.00012 21.1 0.0 0.029 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KZN85176.1 - 0.00039 20.5 0.0 0.0056 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN85176.1 - 0.00071 19.5 0.0 0.015 15.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN85176.1 - 0.001 18.8 0.1 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 KZN85176.1 - 0.0015 17.4 0.4 0.04 12.7 0.0 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KZN85176.1 - 0.0033 16.5 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN85176.1 - 0.0037 17.6 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KZN85176.1 - 0.036 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KZN85176.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KZN85176.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family Zn_clus PF00172.13 KZN85177.1 - 1.5e-09 37.6 8.9 2.8e-09 36.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNARE PF05739.14 KZN85178.1 - 0.011 15.3 0.4 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 SNARE domain Rootletin PF15035.1 KZN85178.1 - 0.033 14.1 0.2 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Synaptobrevin PF00957.16 KZN85178.1 - 0.082 12.5 0.9 0.15 11.7 0.4 1.7 1 1 1 2 2 2 0 Synaptobrevin Arrestin_C PF02752.17 KZN85179.1 - 5.3e-18 65.4 0.1 9.7e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KZN85179.1 - 1.3e-14 54.2 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KZN85179.1 - 0.0039 16.7 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 KZN85180.1 - 0.027 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Glyoxalase PF00903.20 KZN85182.1 - 5.5e-42 142.7 0.1 7.3e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KZN85182.1 - 2e-29 102.3 0.1 4.5e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KZN85182.1 - 2.6e-17 62.8 0.0 1.5e-07 31.3 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KZN85182.1 - 1.7e-07 31.3 0.0 0.0075 16.1 0.0 3.2 2 1 1 3 3 3 2 Glyoxalase-like domain EAP30 PF04157.11 KZN85182.1 - 0.052 12.7 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family PRT_C PF08372.5 KZN85182.1 - 0.15 11.5 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Fungal_trans PF04082.13 KZN85183.1 - 8.7e-23 80.5 0.0 1.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85183.1 - 7.8e-10 38.5 13.2 1.3e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 KZN85184.1 - 2.5e-07 30.5 0.0 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN85184.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 KZN85184.1 - 0.049 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KZN85184.1 - 0.057 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 KZN85184.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KZN85184.1 - 0.075 12.5 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 KZN85184.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_C2 PF00648.16 KZN85185.1 - 1.3e-57 195.1 1.6 1.5e-36 125.9 0.2 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Pkinase PF00069.20 KZN85186.1 - 4.8e-71 238.9 0.0 5.6e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85186.1 - 5e-31 107.7 0.0 6.2e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN85186.1 - 0.00044 19.3 0.0 0.00073 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN85186.1 - 0.0052 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN85186.1 - 0.0071 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KZN85186.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 KZN85187.1 - 4.7e-29 101.5 0.0 9.8e-29 100.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 KZN85188.1 - 5.7e-94 315.4 0.0 7e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.19 KZN85190.1 - 4.2e-87 290.7 53.9 2.2e-49 167.5 15.5 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KZN85190.1 - 7.6e-37 126.6 0.0 1.4e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN85190.1 - 1.6e-34 117.6 0.6 3.2e-27 94.2 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KZN85190.1 - 2.7e-13 49.7 35.2 5.9e-07 28.8 12.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KZN85190.1 - 1.1e-07 31.8 0.0 6e-07 29.4 0.0 2.3 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KZN85190.1 - 1.4e-07 31.7 0.4 2.9e-06 27.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KZN85190.1 - 1.7e-07 30.8 0.0 0.00062 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KZN85190.1 - 2.4e-07 31.0 0.0 0.0069 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN85190.1 - 3.8e-06 27.7 0.0 0.0011 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN85190.1 - 1.1e-05 24.8 0.1 0.0019 17.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN85190.1 - 4.2e-05 23.6 0.2 0.047 13.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN85190.1 - 9.3e-05 21.6 0.0 0.00042 19.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KZN85190.1 - 0.0002 20.9 0.1 0.4 10.1 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KZN85190.1 - 0.00026 20.5 0.2 0.66 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 KZN85190.1 - 0.0003 21.1 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN85190.1 - 0.0016 18.0 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KZN85190.1 - 0.0017 18.2 0.0 0.094 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KZN85190.1 - 0.002 17.6 0.1 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KZN85190.1 - 0.0027 17.6 0.2 0.0027 17.6 0.1 2.0 3 0 0 3 3 1 1 AAA domain AAA_19 PF13245.1 KZN85190.1 - 0.0037 16.9 0.1 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KZN85190.1 - 0.015 15.2 0.2 0.76 9.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.4 KZN85190.1 - 0.015 13.8 0.2 0.88 8.0 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T2SE PF00437.15 KZN85190.1 - 0.017 14.0 0.1 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 KZN85190.1 - 0.018 14.5 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KZN85190.1 - 0.019 14.1 0.1 4.9 6.3 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KZN85190.1 - 0.021 14.4 0.4 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KZN85190.1 - 0.039 14.2 0.3 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KZN85190.1 - 0.043 13.9 0.1 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KZN85190.1 - 0.046 13.4 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KZN85190.1 - 0.064 13.4 0.0 0.85 9.8 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KZN85190.1 - 0.21 11.0 0.1 0.89 9.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DJ-1_PfpI PF01965.19 KZN85193.1 - 8.8e-23 80.3 0.0 1.3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KZN85193.1 - 0.0043 16.5 0.2 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KZN85193.1 - 0.035 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase GMC_oxred_N PF00732.14 KZN85194.1 - 2.8e-75 253.2 0.0 4e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN85194.1 - 5.8e-36 123.9 0.1 2.2e-35 122.0 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN85194.1 - 6.6e-06 25.2 0.0 0.0027 16.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN85194.1 - 4.1e-05 22.6 0.1 0.045 12.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN85194.1 - 0.0061 15.5 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KZN85194.1 - 0.019 14.0 0.1 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family AAA_22 PF13401.1 KZN85195.1 - 0.00043 20.4 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN85195.1 - 0.00046 20.2 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KZN85195.1 - 0.0005 19.9 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KZN85195.1 - 0.00077 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 KZN85195.1 - 0.00078 19.2 0.1 0.0037 17.0 0.0 2.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 KZN85195.1 - 0.021 15.6 0.0 0.068 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KZN85195.1 - 0.023 14.3 0.7 0.095 12.3 0.0 2.3 3 0 0 3 3 3 0 Bacterial dnaA protein KAP_NTPase PF07693.9 KZN85195.1 - 0.038 12.9 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 KZN85195.1 - 0.072 13.0 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KZN85195.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Defensin_1 PF00323.14 KZN85195.1 - 0.16 12.3 0.7 0.55 10.6 0.1 2.2 2 0 0 2 2 2 0 Mammalian defensin AMP-binding PF00501.23 KZN85197.1 - 2.6e-60 203.9 0.0 3.9e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 KZN85197.1 - 1.6e-13 49.4 12.0 4.4e-06 25.9 0.0 7.3 8 0 0 8 8 8 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 KZN85197.1 - 9e-10 38.6 0.0 2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 KZN85197.1 - 5.2e-06 25.9 14.2 1.2 8.7 0.1 6.4 7 0 0 7 7 7 4 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.1 KZN85197.1 - 0.061 14.2 2.6 0.88 10.5 0.2 3.0 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KZN85197.1 - 0.29 9.5 0.1 1.9 6.9 0.1 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF1993 PF09351.5 KZN85199.1 - 8.7e-52 175.2 0.4 9.8e-52 175.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Prefoldin_2 PF01920.15 KZN85199.1 - 0.043 13.5 0.9 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF3196 PF11428.3 KZN85199.1 - 0.066 12.5 0.6 0.086 12.1 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) NTPase_1 PF03266.10 KZN85199.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 NTPase IF-2B PF01008.12 KZN85199.1 - 0.14 11.0 1.0 0.2 10.6 0.7 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family CCD PF07860.6 KZN85200.1 - 0.048 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region Pec_lyase_C PF00544.14 KZN85201.1 - 1.1e-20 74.0 4.0 1.7e-20 73.3 2.8 1.3 1 0 0 1 1 1 1 Pectate lyase DUF222 PF02720.12 KZN85202.1 - 0.051 12.6 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF222) DUF3716 PF12511.3 KZN85203.1 - 2.2e-08 33.5 2.1 4e-08 32.7 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Fungal_trans_2 PF11951.3 KZN85205.1 - 9.8e-10 37.5 0.1 5.3e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85205.1 - 1.4e-06 28.1 15.4 2.6e-06 27.2 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K1 PF02960.9 KZN85206.1 - 0.0019 18.2 1.9 0.0053 16.8 1.3 1.8 1 0 0 1 1 1 1 K1 glycoprotein DUF2371 PF10177.4 KZN85206.1 - 0.03 14.1 0.7 0.35 10.7 0.0 2.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) IncA PF04156.9 KZN85206.1 - 0.12 11.9 3.5 2.3 7.7 3.4 2.3 2 0 0 2 2 2 0 IncA protein F-box PF00646.28 KZN85207.1 - 0.014 15.0 0.0 0.038 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain Toxin_52 PF15605.1 KZN85207.1 - 0.086 12.7 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative toxin 52 Ank_2 PF12796.2 KZN85208.1 - 4.9e-148 481.9 35.8 7e-22 77.5 0.1 13.1 4 3 8 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 KZN85208.1 - 1.1e-117 378.4 84.6 6.2e-09 35.2 0.0 27.4 28 0 0 28 28 28 24 Ankyrin repeat Ank_4 PF13637.1 KZN85208.1 - 3.8e-102 333.0 40.5 4e-11 43.1 0.2 20.9 8 5 14 23 23 23 20 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN85208.1 - 1.9e-90 287.5 45.6 2.9e-06 26.9 0.0 27.5 28 0 0 28 28 28 17 Ankyrin repeat Ank_5 PF13857.1 KZN85208.1 - 7.8e-83 270.6 54.5 1e-09 38.3 0.4 20.3 11 6 9 21 21 21 18 Ankyrin repeats (many copies) NACHT PF05729.7 KZN85208.1 - 7.2e-08 32.2 0.0 4.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KZN85208.1 - 8.9e-05 22.5 0.7 0.0023 17.9 0.0 3.2 3 2 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KZN85208.1 - 0.0051 16.6 0.4 0.055 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Laminin_I PF06008.9 KZN85208.1 - 0.14 11.4 1.1 0.24 10.6 0.8 1.3 1 0 0 1 1 1 0 Laminin Domain I RNA_helicase PF00910.17 KZN85208.1 - 0.31 11.2 0.0 0.75 10.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.20 KZN85210.1 - 7.4e-19 67.9 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85210.1 - 1.8e-05 23.9 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WGG PF10273.4 KZN85211.1 - 9.1e-31 105.7 0.4 1.8e-30 104.8 0.3 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KZN85211.1 - 0.81 9.7 0.1 0.81 9.7 0.1 2.2 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_60s PF00428.14 KZN85211.1 - 4.9 7.6 8.5 0.67 10.3 3.1 1.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.22 KZN85212.1 - 1.6e-39 135.3 0.0 2.6e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KZN85212.1 - 3.4e-20 72.0 0.1 8.4e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KZN85212.1 - 1.8e-05 24.7 0.0 4.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN85212.1 - 0.0034 17.3 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KZN85212.1 - 0.012 14.2 0.1 0.022 13.4 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit PAT1 PF09770.4 KZN85212.1 - 6.5 4.8 26.1 9.5 4.3 18.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ran-binding PF05508.6 KZN85213.1 - 4.7e-103 344.2 0.1 6e-103 343.9 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.12 KZN85214.1 - 1.4e-16 59.9 0.7 3.4e-16 58.7 0.5 1.7 1 0 0 1 1 1 1 BSD domain DUF1759 PF03564.10 KZN85214.1 - 0.055 13.2 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) MDMPI_N PF11716.3 KZN85214.1 - 0.97 9.8 4.4 1.4 9.3 1.6 2.3 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain GFO_IDH_MocA PF01408.17 KZN85215.1 - 3.6e-22 79.1 0.0 6.2e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KZN85215.1 - 6.1e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 KZN85215.1 - 0.12 12.2 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Rad4 PF03835.10 KZN85216.1 - 1.2e-34 118.8 0.1 3.1e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KZN85216.1 - 7.7e-28 96.0 0.0 1.4e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KZN85216.1 - 3.3e-21 74.5 0.0 7.1e-21 73.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KZN85216.1 - 1.4e-12 47.7 2.3 2.9e-12 46.6 0.0 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KZN85216.1 - 0.0076 16.4 0.0 0.03 14.5 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily Methyltransf_23 PF13489.1 KZN85217.1 - 3.3e-20 72.4 0.0 5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN85217.1 - 1.1e-09 38.8 0.0 2.7e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85217.1 - 5.8e-08 32.4 0.0 5.5e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85217.1 - 6.9e-07 29.6 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN85217.1 - 2.1e-06 28.1 0.0 9.7e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN85217.1 - 0.00084 18.5 0.0 0.0042 16.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KZN85217.1 - 0.0013 19.0 0.0 0.0054 17.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN85217.1 - 0.0016 17.4 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KZN85217.1 - 0.0017 17.5 0.0 0.0057 15.8 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KZN85217.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KZN85217.1 - 0.012 15.6 0.0 0.04 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KZN85217.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Proteasome PF00227.21 KZN85219.1 - 2.7e-44 150.7 0.1 3.6e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KZN85219.1 - 1.5e-12 46.5 0.3 3.4e-12 45.3 0.2 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF1664 PF07889.7 KZN85220.1 - 0.31 10.8 0.9 2.5 7.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CbiG_mid PF11761.3 KZN85222.1 - 0.11 12.7 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis central region KH_1 PF00013.24 KZN85223.1 - 8.8e-42 140.5 2.0 4.8e-16 58.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KZN85223.1 - 1.3e-30 104.4 10.2 1.4e-10 40.5 1.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KZN85223.1 - 2.7e-12 46.0 2.7 0.004 16.6 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KZN85223.1 - 4.8e-05 22.9 0.1 1.5 8.4 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KZN85223.1 - 0.0028 17.4 5.8 1.4 8.7 0.2 3.2 3 0 0 3 3 3 2 NusA-like KH domain AceK PF06315.6 KZN85224.1 - 0.014 13.6 4.8 0.023 12.9 3.3 1.3 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) CENP-K PF11802.3 KZN85224.1 - 0.047 12.9 10.1 0.16 11.1 0.0 2.6 2 1 0 2 2 2 0 Centromere-associated protein K DUF3510 PF12022.3 KZN85224.1 - 1.7 8.7 6.9 0.16 12.0 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) DEAD PF00270.24 KZN85225.1 - 1e-22 80.4 0.0 5.5e-21 74.7 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN85225.1 - 4.2e-18 64.9 0.1 4.6e-15 55.2 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.5 KZN85225.1 - 8.2e-15 54.4 0.0 2.1e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 KZN85225.1 - 1.8e-07 30.8 0.0 6.6e-07 28.9 0.0 2.1 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 KZN85225.1 - 0.0021 17.9 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.1 KZN85226.1 - 9.3e-29 99.1 1.4 9.3e-29 99.1 1.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KZN85226.1 - 5e-27 93.4 16.4 8.3e-09 35.3 0.1 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KZN85226.1 - 6.7e-24 83.4 19.1 1.9e-06 27.5 0.0 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KZN85226.1 - 4.3e-14 52.0 6.3 1.7e-05 24.6 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 KZN85226.1 - 6.3e-14 51.4 7.1 0.0012 18.9 0.2 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KZN85226.1 - 7.8e-12 44.4 9.8 0.0003 20.4 0.0 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KZN85226.1 - 1.2e-11 44.0 0.2 1.3e-05 24.6 0.1 5.2 5 0 0 5 5 5 1 Kelch motif Bd3614-deam PF14439.1 KZN85226.1 - 4.8 7.0 6.1 15 5.4 2.4 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase Pyridoxal_deC PF00282.14 KZN85227.1 - 1.4e-28 99.4 0.0 2e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KZN85227.1 - 0.00068 18.8 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KZN85227.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 KZN85227.1 - 0.02 13.3 0.0 0.058 11.8 0.0 1.6 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 KZN85227.1 - 0.022 13.4 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V MFS_1 PF07690.11 KZN85228.1 - 2.8e-32 111.8 41.1 2.8e-32 111.8 28.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN85228.1 - 1.1e-16 60.2 21.3 1.4e-16 59.8 14.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN85228.1 - 3.8e-12 45.5 11.7 3.8e-12 45.5 8.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KZN85228.1 - 2.9e-05 22.4 2.8 2.9e-05 22.4 1.9 3.1 3 0 0 3 3 3 1 Transmembrane secretion effector Abhydrolase_6 PF12697.2 KZN85229.1 - 9.2e-14 51.8 0.0 3.1e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN85229.1 - 4.3e-10 39.5 0.0 2e-09 37.3 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN85229.1 - 9.9e-10 38.3 0.0 6e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN85229.1 - 0.0037 16.5 0.0 0.018 14.2 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KZN85229.1 - 0.013 15.3 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KZN85229.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 KZN85229.1 - 0.098 12.0 0.0 3 7.1 0.0 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Mon1 PF03164.9 KZN85230.1 - 7.1e-120 400.3 0.0 8.6e-120 400.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 KZN85231.1 - 4.6e-120 400.0 0.0 1e-119 398.9 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal Hpt PF01627.18 KZN85231.1 - 0.027 14.4 1.1 1.2 9.2 0.0 3.8 3 0 0 3 3 3 0 Hpt domain MazG PF03819.12 KZN85231.1 - 0.15 12.0 0.2 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain MBOAT PF03062.14 KZN85234.1 - 2.5e-41 141.8 11.1 5.3e-41 140.8 7.7 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family AOX PF01786.12 KZN85235.1 - 3.3e-92 307.5 0.0 4.2e-92 307.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase KAR9 PF08580.5 KZN85236.1 - 9.6e-145 483.5 3.1 9.6e-145 483.5 2.1 2.6 2 1 1 3 3 3 1 Yeast cortical protein KAR9 DUF2746 PF10874.3 KZN85236.1 - 0.018 15.2 0.7 6.1 7.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) NPV_P10 PF05531.7 KZN85236.1 - 0.29 11.4 5.7 0.28 11.4 0.4 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Acetyltransf_1 PF00583.19 KZN85237.1 - 1.9e-06 27.8 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KZN85237.1 - 8.5e-06 25.9 0.0 1.5e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN85237.1 - 0.0025 17.6 0.0 0.0037 17.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN85237.1 - 0.0027 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN85237.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 KZN85237.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN85237.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 KZN85238.1 - 3.6e-08 33.0 0.0 6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN85238.1 - 8.4e-07 29.1 0.1 1.1e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KZN85238.1 - 4.9e-05 23.7 0.1 6.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like CSTF2_hinge PF14327.1 KZN85238.1 - 0.13 12.3 0.2 20 5.3 0.0 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Methyltransf_26 PF13659.1 KZN85239.1 - 1.1e-17 64.1 0.1 1.6e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN85239.1 - 0.00037 19.9 0.3 0.00092 18.6 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase small domain LSM PF01423.17 KZN85240.1 - 6.2e-12 44.8 0.0 2.9e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 LSM domain DUF2763 PF10961.3 KZN85240.1 - 3.9 7.9 7.2 6.9 7.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 KZN85240.1 - 4.4 5.6 9.0 5.4 5.3 6.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2_4 PF13894.1 KZN85241.1 - 4.5e-05 23.4 1.5 0.03 14.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN85241.1 - 8.2e-05 22.7 0.8 0.32 11.4 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN85241.1 - 0.035 14.3 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KZN85241.1 - 0.036 13.9 0.7 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger GAGA PF09237.6 KZN85241.1 - 0.27 10.8 1.7 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 GAGA factor AD PF09793.4 KZN85242.1 - 5.7e-25 86.9 0.0 9.5e-25 86.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain YodL PF14191.1 KZN85242.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 YodL-like 2-Hacid_dh_C PF02826.14 KZN85243.1 - 7.1e-55 184.9 0.0 1.1e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN85243.1 - 5.2e-36 123.0 0.1 8.6e-36 122.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 KZN85243.1 - 0.0056 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 KZN85243.1 - 0.012 15.1 0.3 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KZN85243.1 - 0.019 14.8 0.2 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KZN85243.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KZN85243.1 - 0.042 13.2 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DAO PF01266.19 KZN85243.1 - 0.1 11.4 1.2 1.2 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ACT PF01842.20 KZN85243.1 - 0.13 11.7 2.1 1.8 8.1 0.0 3.6 4 0 0 4 4 4 0 ACT domain Fungal_trans_2 PF11951.3 KZN85244.1 - 3.5e-07 29.1 0.1 1.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85244.1 - 9.2e-07 28.6 7.9 1.8e-06 27.7 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe-ADH PF00465.14 KZN85245.1 - 1e-103 346.8 0.1 1.3e-103 346.5 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KZN85245.1 - 1.8e-15 56.9 0.0 1.3e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KZN85245.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Bys1 PF04681.7 KZN85246.1 - 2.7e-08 33.6 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Arylsulfotran_2 PF14269.1 KZN85247.1 - 1.6e-114 382.1 9.0 2e-114 381.7 6.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Cytochrome-c551 PF10643.4 KZN85248.1 - 2.2 7.4 5.5 4.3 6.5 3.8 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 ADH_zinc_N PF00107.21 KZN85249.1 - 2.4e-26 91.8 0.4 3.7e-26 91.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN85249.1 - 1.5e-22 79.4 0.4 2.8e-22 78.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN85249.1 - 1.6e-06 28.9 0.0 3.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KZN85249.1 - 0.037 14.0 0.8 0.059 13.3 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF336 PF03928.9 KZN85251.1 - 9.7e-17 61.0 3.7 5e-15 55.4 2.6 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF336) HSP70 PF00012.15 KZN85253.1 - 6.7e-262 869.7 13.9 7.6e-262 869.5 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KZN85253.1 - 1.2e-16 60.2 1.4 2.3e-15 55.9 0.3 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KZN85253.1 - 0.0059 15.4 2.3 0.015 14.1 0.2 2.4 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KZN85253.1 - 0.1 11.6 6.3 0.22 10.5 0.1 3.3 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KZN85253.1 - 1.5 8.6 4.8 4.6 7.0 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA GTP_EFTU PF00009.22 KZN85254.1 - 4.7e-51 172.9 0.0 7.8e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KZN85254.1 - 1.7e-16 60.1 5.4 3.3e-16 59.1 3.8 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KZN85254.1 - 1.3e-09 38.0 0.0 3.2e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN85254.1 - 3.3e-08 33.4 0.0 8.3e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KZN85254.1 - 1.4e-07 31.5 0.0 7.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KZN85254.1 - 8.8e-05 22.9 0.0 0.00049 20.5 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KZN85254.1 - 0.00034 19.8 0.1 0.0007 18.8 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KZN85254.1 - 0.00036 19.8 0.1 0.031 13.4 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KZN85254.1 - 0.0036 16.5 0.0 1.7 7.8 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Septin PF00735.13 KZN85254.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KZN85254.1 - 0.018 14.2 0.6 0.53 9.5 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KZN85254.1 - 0.023 14.5 0.1 3 7.6 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Met_asp_mut_E PF06368.6 KZN85254.1 - 0.075 11.1 0.2 0.2 9.7 0.0 1.7 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) UCH_1 PF13423.1 KZN85255.1 - 2.6e-66 224.0 0.6 3.3e-66 223.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KZN85255.1 - 2.1e-21 76.9 0.0 4.2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KZN85255.1 - 4.7e-07 29.1 0.0 4.1e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.13 KZN85256.1 - 1.9e-14 53.1 0.0 4.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GATase PF00117.23 KZN85257.1 - 0.00046 19.6 0.0 0.00068 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pkinase PF00069.20 KZN85258.1 - 2.7e-12 46.4 0.0 4.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85258.1 - 9.1e-08 31.4 0.0 1.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN85258.1 - 0.11 12.2 0.7 0.48 10.0 0.5 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_Tnp_ISL3 PF13542.1 KZN85259.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.1 KZN85259.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF3529 PF12046.3 KZN85260.1 - 0.06 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) VHS PF00790.14 KZN85261.1 - 1.5e-35 121.8 1.0 2.7e-35 121.0 0.7 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KZN85261.1 - 3.7e-16 58.2 0.0 8.9e-16 57.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN85261.1 - 2e-15 56.1 0.1 3.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KZN85261.1 - 1.5e-14 53.1 0.0 3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 KZN85262.1 - 6.7e-70 235.2 0.0 1.1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85262.1 - 3e-44 151.0 0.0 4.9e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KZN85262.1 - 6.2e-21 74.5 1.6 1.1e-20 73.7 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 KZN85262.1 - 1.2e-06 27.6 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN85262.1 - 0.021 14.5 3.1 0.27 10.9 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 KZN85262.1 - 0.057 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain Glyco_hydro_43 PF04616.9 KZN85264.1 - 4.1e-32 111.3 6.3 5.1e-32 111.1 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SprB PF13573.1 KZN85264.1 - 0.14 11.8 1.3 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 SprB repeat KH_1 PF00013.24 KZN85265.1 - 3.9e-86 282.6 21.2 2.3e-12 46.3 0.2 13.1 14 0 0 14 14 14 9 KH domain KH_3 PF13014.1 KZN85265.1 - 4.6e-63 208.0 17.0 5.2e-09 35.5 0.9 12.5 13 0 0 13 13 13 10 KH domain SLS PF14611.1 KZN85265.1 - 1.3e-13 50.8 1.5 0.23 10.8 0.0 7.6 6 3 3 9 9 9 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 KZN85265.1 - 3e-10 39.4 28.8 0.003 17.0 0.2 7.3 7 1 1 8 8 8 6 KH domain BMC PF00936.14 KZN85265.1 - 8.3e-06 25.4 0.8 8.5 6.1 0.1 5.6 6 0 0 6 6 6 3 BMC domain KH_5 PF13184.1 KZN85265.1 - 0.0054 16.4 8.6 21 5.0 0.1 6.7 7 0 0 7 7 7 0 NusA-like KH domain KH_4 PF13083.1 KZN85265.1 - 0.022 14.3 6.2 14 5.4 0.0 4.8 5 0 0 5 5 5 0 KH domain Acylphosphatase PF00708.13 KZN85265.1 - 0.13 12.3 1.4 1.7 8.8 0.1 3.3 3 0 0 3 3 3 0 Acylphosphatase Cyt-b5 PF00173.23 KZN85266.1 - 2.4e-25 88.1 0.0 3.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 KZN85266.1 - 0.053 13.4 0.2 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 YqzH-like protein UCH PF00443.24 KZN85267.1 - 8.6e-57 192.2 0.0 1.4e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN85267.1 - 2.7e-29 102.5 0.0 4.2e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 KZN85267.1 - 3.1e-06 27.1 0.3 1.2e-05 25.2 0.0 2.1 3 0 0 3 3 3 1 USP8 dimerisation domain Rhodanese PF00581.15 KZN85267.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.14 KZN85268.1 - 2e-39 134.4 1.0 1.7e-38 131.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KZN85268.1 - 2.3e-16 59.4 2.4 3.7e-16 58.7 1.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KZN85268.1 - 0.00036 19.8 16.5 0.0061 16.0 1.4 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KZN85268.1 - 0.018 14.4 0.3 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 KZN85268.1 - 0.051 13.4 0.3 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4598 PF15370.1 KZN85269.1 - 1.4 9.2 8.0 0.37 11.0 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) KAAG1 PF15354.1 KZN85269.1 - 1.6 9.1 16.8 0.9 9.9 1.6 3.8 3 0 0 3 3 3 0 Kidney-associated antigen 1 p450 PF00067.17 KZN85270.1 - 1.7e-72 244.4 0.0 1.9e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ion_trans_2 PF07885.11 KZN85270.1 - 0.082 12.6 0.9 0.19 11.4 0.6 1.7 1 0 0 1 1 1 0 Ion channel DUF3684 PF12449.3 KZN85270.1 - 0.22 9.0 0.1 0.3 8.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) RCC1 PF00415.13 KZN85271.1 - 2.1e-23 82.2 0.4 2.8e-06 27.4 0.0 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KZN85271.1 - 1.5e-11 44.2 0.2 5.1e-10 39.3 0.2 2.4 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.1 KZN85271.1 - 1.1e-10 40.7 3.7 3.8e-07 29.5 0.1 3.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 KZN85271.1 - 1.4e-09 38.2 0.2 0.00016 22.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN85271.1 - 3.4e-06 26.7 0.4 0.018 15.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KZN85271.1 - 0.00014 22.0 0.1 0.0015 18.8 0.1 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN85271.1 - 0.0053 16.9 0.1 2.1 8.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KZN85271.1 - 0.22 11.3 1.3 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat Dynamin_N PF00350.18 KZN85272.1 - 7.7e-29 100.6 0.0 1.7e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KZN85272.1 - 2.2e-20 72.6 1.4 5.3e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KZN85272.1 - 0.001 18.9 0.1 0.0082 16.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KZN85272.1 - 0.027 14.9 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DNA_primase_lrg PF04104.9 KZN85272.1 - 0.42 9.8 2.3 2.3 7.4 0.0 2.9 4 0 0 4 4 4 0 Eukaryotic and archaeal DNA primase, large subunit LIP PF03583.9 KZN85274.1 - 1.1e-67 228.2 0.2 1.7e-67 227.6 0.2 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KZN85274.1 - 1.8e-07 31.3 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN85274.1 - 6.5e-07 28.7 0.0 0.00047 19.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN85274.1 - 9.1e-07 28.7 0.0 2.3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KZN85274.1 - 0.00035 20.0 0.0 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 KZN85274.1 - 0.022 14.0 0.2 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family ATG13 PF10033.4 KZN85275.1 - 4.8e-79 265.0 0.0 8.3e-79 264.2 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 6PGD PF00393.14 KZN85276.1 - 1.4e-134 447.9 0.0 1.6e-134 447.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KZN85276.1 - 9e-52 175.1 0.0 1.3e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN85276.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 KZN85276.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.17 KZN85277.1 - 2.2e-15 55.9 0.0 3.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN85277.1 - 1.5e-09 37.6 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med13_C PF06333.7 KZN85278.1 - 4.6e-104 348.2 0.0 8.3e-104 347.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KZN85278.1 - 5.3e-74 249.2 0.0 8.6e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Rsm1 PF08600.5 KZN85278.1 - 0.083 12.7 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.7 KZN85279.1 - 1.2e-13 50.3 0.1 3.4e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KZN85279.1 - 0.0047 16.7 0.0 3.9 7.4 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat APH PF01636.18 KZN85280.1 - 1.3e-08 34.8 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3602 PF12223.3 KZN85281.1 - 0.0021 18.4 2.0 0.0022 18.3 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) DUF3990 PF13151.1 KZN85283.1 - 0.0037 16.6 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3990) Gluconate_2-dh3 PF13618.1 KZN85283.1 - 0.0045 17.1 2.2 1.8 8.6 0.1 2.2 1 1 1 2 2 2 2 Gluconate 2-dehydrogenase subunit 3 MgtE_N PF03448.12 KZN85283.1 - 0.02 15.1 4.2 2.9 8.2 0.2 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain SRP9-21 PF05486.7 KZN85285.1 - 0.018 14.7 0.5 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) His_Phos_1 PF00300.17 KZN85286.1 - 1.7e-15 57.4 0.1 5.1e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.20 KZN85287.1 - 2.3e-75 253.7 0.0 3.6e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 KZN85288.1 - 2.6e-37 126.9 20.0 4.4e-31 106.9 3.6 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KZN85288.1 - 3.1e-06 27.1 21.3 6.2e-06 26.1 3.9 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN85288.1 - 2e-05 24.6 9.6 4.8e-05 23.4 3.6 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type ASCH PF04266.9 KZN85288.1 - 0.011 16.0 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 ASCH domain DUF2777 PF10949.3 KZN85288.1 - 0.021 14.5 0.5 0.038 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) zf-C2H2 PF00096.21 KZN85288.1 - 0.18 12.2 23.6 0.15 12.4 2.0 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF21 PF01595.15 KZN85289.1 - 4e-32 110.9 0.1 6.5e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KZN85289.1 - 3.5e-06 26.6 0.3 0.014 15.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain ERM PF00769.14 KZN85290.1 - 5.9e-06 26.0 19.4 5.9e-06 26.0 13.4 3.6 2 1 1 3 3 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 KZN85290.1 - 5.1e-05 23.0 18.4 5.1e-05 23.0 12.8 4.0 3 1 0 4 4 4 3 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 KZN85290.1 - 0.0024 17.2 6.5 0.0024 17.2 4.5 3.9 2 1 2 4 4 3 2 Protein of unknown function (DUF3450) IncA PF04156.9 KZN85290.1 - 0.0035 16.9 2.1 0.0035 16.9 1.5 4.4 2 1 1 3 3 3 1 IncA protein ADIP PF11559.3 KZN85290.1 - 0.0069 16.3 11.1 0.0069 16.3 7.7 5.9 2 1 4 6 6 6 2 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KZN85290.1 - 0.014 15.1 4.6 0.014 15.1 3.2 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 KZN85290.1 - 0.028 14.5 2.4 0.028 14.5 1.7 4.9 3 1 1 4 4 4 0 Syntaxin DUF4055 PF13264.1 KZN85290.1 - 0.03 14.3 0.9 0.03 14.3 0.6 3.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4055) Myosin_tail_1 PF01576.14 KZN85290.1 - 0.67 7.5 62.9 0.36 8.4 7.7 2.6 2 1 0 2 2 2 0 Myosin tail DUF3584 PF12128.3 KZN85290.1 - 1.8 5.7 56.0 0.29 8.4 7.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HALZ PF02183.13 KZN85290.1 - 2.1 8.1 19.0 3.1 7.5 4.9 4.6 3 1 1 4 4 4 0 Homeobox associated leucine zipper Filament PF00038.16 KZN85290.1 - 4.5 6.6 50.1 0.63 9.4 5.4 2.6 2 1 0 2 2 2 0 Intermediate filament protein FlxA PF14282.1 KZN85290.1 - 8.1 6.4 36.0 0.23 11.4 5.5 4.4 2 1 1 4 4 4 0 FlxA-like protein MR_MLE_C PF13378.1 KZN85291.1 - 5.6e-18 64.9 0.1 8.9e-18 64.2 0.1 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KZN85291.1 - 1.2e-16 60.7 0.0 2.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HMGL-like PF00682.14 KZN85291.1 - 0.079 12.6 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 HMGL-like Gly_transf_sug PF04488.10 KZN85292.1 - 1.8e-11 44.2 0.0 4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KZN85292.1 - 0.00038 19.6 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein AhpC-TSA PF00578.16 KZN85293.1 - 9.8e-33 112.4 0.0 1.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KZN85293.1 - 1.8e-13 49.8 0.5 3e-13 49.1 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KZN85293.1 - 1e-12 47.8 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Glyco_hydro_3 PF00933.16 KZN85294.1 - 2.2e-92 309.2 0.0 3.1e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN85294.1 - 9.9e-52 175.7 0.0 2.6e-50 171.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN85294.1 - 9.4e-21 73.5 0.2 1.6e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 KZN85295.1 - 2e-43 148.4 83.8 6.4e-41 140.2 41.1 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85295.1 - 1.7e-15 56.5 46.3 2.1e-15 56.2 13.6 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KZN85295.1 - 1.6e-12 46.4 30.8 2.7e-12 45.7 21.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KZN85295.1 - 0.01 15.5 6.0 0.45 10.3 0.1 3.4 2 1 1 3 3 3 0 MFS_1 like family Fungal_trans PF04082.13 KZN85296.1 - 1.7e-13 50.0 0.3 3.5e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85296.1 - 9.6e-10 38.2 10.9 9.6e-10 38.2 7.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn-ribbon_8 PF09723.5 KZN85296.1 - 2.7 8.0 8.5 4.4 7.3 0.0 3.7 3 0 0 3 3 3 0 Zinc ribbon domain Methyltransf_23 PF13489.1 KZN85297.1 - 2.6e-10 40.2 0.0 3.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN85297.1 - 1.5e-08 34.9 0.0 3.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85297.1 - 2e-07 30.7 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN85297.1 - 1.3e-05 25.4 0.0 6.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN85297.1 - 6.1e-05 23.5 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85297.1 - 0.00018 21.9 0.0 0.00048 20.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN85297.1 - 0.019 14.9 0.0 0.077 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.7 KZN85297.1 - 0.039 13.2 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_M20 PF01546.23 KZN85298.1 - 1.8e-23 83.0 0.0 1e-22 80.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KZN85298.1 - 5.9e-09 35.4 11.6 0.014 15.2 0.1 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.9 KZN85298.1 - 3.5e-07 29.9 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KZN85298.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PT PF04886.7 KZN85299.1 - 0.00033 19.9 7.8 0.00033 19.9 5.4 3.3 4 0 0 4 4 4 1 PT repeat TraQ PF09679.5 KZN85299.1 - 0.072 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF605 PF04652.11 KZN85299.1 - 2.8 7.2 22.5 0.35 10.2 7.9 2.1 2 0 0 2 2 2 0 Vta1 like Arginosuc_synth PF00764.14 KZN85300.1 - 4.1e-158 526.4 0.0 4.7e-158 526.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KZN85300.1 - 0.00032 20.2 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KZN85300.1 - 0.0075 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KZN85300.1 - 0.021 13.4 0.0 0.031 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Transket_pyr PF02779.19 KZN85301.1 - 7.5e-44 149.3 0.0 1.3e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KZN85301.1 - 1.3e-30 105.8 0.0 5.8e-30 103.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain IBR PF01485.16 KZN85302.1 - 5e-06 26.3 9.0 5e-06 26.3 6.2 3.3 2 1 1 3 3 3 1 IBR domain zf-RING_5 PF14634.1 KZN85302.1 - 0.00061 19.4 3.5 0.00061 19.4 2.5 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN85302.1 - 0.012 15.4 5.4 0.012 15.4 3.8 3.1 2 1 1 3 3 3 0 Ring finger domain DUF2719 PF10891.3 KZN85302.1 - 0.013 15.1 0.7 0.028 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) HrpB1_HrpK PF09613.5 KZN85302.1 - 0.064 12.7 0.6 0.26 10.7 0.1 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) NmrA PF05368.8 KZN85303.1 - 3.6e-23 82.0 0.0 5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN85303.1 - 4e-19 69.3 0.0 5.7e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN85303.1 - 1.5e-06 27.8 0.1 2.6e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KZN85303.1 - 3.7e-05 22.8 0.1 5.5e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KZN85303.1 - 0.0019 16.9 0.0 0.0036 16.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN85303.1 - 0.0062 15.5 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 KZN85303.1 - 0.0077 16.1 0.5 0.045 13.6 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KZN85303.1 - 0.1 11.4 0.1 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain IBR PF01485.16 KZN85304.1 - 0.0002 21.1 8.4 0.0002 21.1 5.8 3.9 2 1 1 3 3 3 2 IBR domain zf-RING_6 PF14835.1 KZN85304.1 - 0.0043 16.8 1.2 0.0043 16.8 0.8 3.2 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KZN85304.1 - 0.024 14.3 9.6 0.024 14.3 6.7 3.6 3 2 0 3 3 3 0 zinc-RING finger domain zf-RING_2 PF13639.1 KZN85304.1 - 5.9 6.7 27.5 0.061 13.1 5.3 3.9 3 1 0 3 3 3 0 Ring finger domain DUF572 PF04502.8 KZN85305.1 - 1e-48 166.2 2.9 1.1e-48 166.0 2.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Filament PF00038.16 KZN85306.1 - 8.9e-06 25.3 159.3 0.0035 16.8 13.2 8.5 2 1 6 9 9 9 5 Intermediate filament protein Fib_alpha PF08702.5 KZN85306.1 - 0.0008 19.5 4.4 0.0008 19.5 3.1 9.8 2 1 6 10 10 10 3 Fibrinogen alpha/beta chain family GAS PF13851.1 KZN85306.1 - 0.0019 17.3 8.4 0.0019 17.3 5.8 9.1 2 1 6 9 9 9 2 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.7 KZN85306.1 - 0.2 11.5 18.3 1.8 8.5 0.0 8.1 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat PTPA PF03095.10 KZN85308.1 - 5.2e-113 377.1 0.0 6.1e-113 376.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Zip PF02535.17 KZN85309.1 - 5.7e-52 176.6 0.7 7.2e-52 176.3 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Med3 PF11593.3 KZN85310.1 - 0.097 11.8 35.6 0.13 11.4 24.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HC2 PF07382.6 KZN85310.1 - 1 9.2 83.5 19 5.0 58.0 1.9 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 TFIIA PF03153.8 KZN85310.1 - 1.8 8.3 24.8 2.6 7.8 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dapper PF15268.1 KZN85310.1 - 5.3 5.7 27.9 6.5 5.4 19.4 1.0 1 0 0 1 1 1 0 Dapper IMS PF00817.15 KZN85311.1 - 2.7e-42 144.0 0.0 5.4e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KZN85311.1 - 2.6e-20 72.6 0.0 6.1e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KZN85311.1 - 3.1e-13 49.5 14.7 4.9e-07 29.6 0.4 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KZN85311.1 - 3.9e-06 26.9 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 KZN85311.1 - 7.7e-06 25.9 0.0 3.5e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 KZN85311.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 KZN85311.1 - 0.0032 17.4 0.0 0.0099 15.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 KZN85311.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.23 KZN85312.1 - 1.8e-31 108.0 0.1 8.8e-31 105.7 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RING_2 PF13639.1 KZN85313.1 - 6.5e-14 51.4 9.6 1e-13 50.8 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN85313.1 - 3.8e-08 32.8 4.2 5.6e-08 32.3 2.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN85313.1 - 1.2e-07 31.6 6.1 2.4e-07 30.7 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN85313.1 - 2.7e-07 30.5 8.3 4.2e-07 29.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN85313.1 - 1e-05 25.0 8.1 1.6e-05 24.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN85313.1 - 5.1e-05 22.9 6.0 7.6e-05 22.3 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KZN85313.1 - 0.00092 19.0 2.9 0.0017 18.1 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KZN85313.1 - 0.077 12.5 3.2 0.13 11.8 2.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KZN85313.1 - 0.1 12.3 6.0 0.17 11.5 4.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 KZN85313.1 - 0.42 10.3 5.3 0.94 9.2 3.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KZN85313.1 - 0.93 9.4 6.0 2 8.3 4.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 KZN85313.1 - 4 7.5 6.8 6.3 6.8 4.7 1.3 1 0 0 1 1 1 0 RING-like domain Peptidase_M3 PF01432.15 KZN85315.1 - 2.2e-118 396.2 0.0 3.2e-118 395.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 ApoO PF09769.4 KZN85316.1 - 1.3e-46 158.1 0.1 3.9e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.9 KZN85317.1 - 6.2e-41 139.6 0.0 4.4e-40 136.8 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 KZN85318.1 - 8.8e-50 168.4 0.0 1.1e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KZN85318.1 - 4.7e-10 39.3 0.0 6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KZN85318.1 - 1.5e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KZN85318.1 - 2.8e-09 36.7 0.0 3.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 KZN85318.1 - 1.5e-07 31.9 0.0 2.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KZN85318.1 - 1.1e-06 28.1 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KZN85318.1 - 2.2e-06 27.3 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KZN85318.1 - 0.0062 15.6 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_3 PF01596.12 KZN85318.1 - 0.0093 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KZN85318.1 - 0.049 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_5 PF01795.14 KZN85318.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family DUF3591 PF12157.3 KZN85319.1 - 1.1e-191 637.2 0.3 1.4e-191 636.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KZN85319.1 - 0.0039 16.8 1.2 0.0088 15.6 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KZN85319.1 - 0.015 15.2 0.9 0.025 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 KZN85320.1 - 6.5e-47 159.8 0.4 9.1e-25 87.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85320.1 - 2.1e-20 72.9 0.0 3.8e-12 45.8 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KZN85320.1 - 0.00099 18.9 0.4 0.0026 17.5 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KZN85320.1 - 0.0079 16.7 0.0 0.039 14.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KZN85320.1 - 0.2 10.4 0.1 0.46 9.2 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase AAA PF00004.24 KZN85321.1 - 5.9e-17 62.1 0.0 1.2e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KZN85321.1 - 0.00053 19.6 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KZN85321.1 - 0.0025 17.8 0.0 0.0095 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN85321.1 - 0.0039 17.3 0.1 0.025 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN85321.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KZN85321.1 - 0.081 12.8 0.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KZN85321.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1509 PF07420.6 KZN85321.1 - 0.6 9.3 8.1 1.1 8.5 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Fungal_trans PF04082.13 KZN85322.1 - 8.4e-35 119.8 0.0 1.4e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85323.1 - 2.6e-05 24.0 10.3 3.9e-05 23.4 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.5 KZN85324.1 - 7.2e-96 320.8 0.0 9.5e-96 320.4 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KZN85324.1 - 2.5e-16 58.9 0.0 4.6e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 KZN85324.1 - 0.12 12.3 8.1 1.3 9.1 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) PP2C PF00481.16 KZN85325.1 - 4.8e-51 173.5 0.0 8.2e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KZN85325.1 - 1.3e-48 161.9 54.7 7.6e-07 28.6 0.5 12.5 7 3 6 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN85325.1 - 5.2e-39 131.8 56.9 1.6e-07 30.9 0.5 10.8 7 3 5 12 12 12 9 Leucine rich repeat Guanylate_cyc PF00211.15 KZN85325.1 - 2.3e-26 92.2 0.0 4.2e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KZN85325.1 - 1.5e-20 70.0 60.9 0.32 11.1 0.5 18.3 17 1 1 18 18 18 9 Leucine Rich Repeat LRR_7 PF13504.1 KZN85325.1 - 2e-08 33.0 45.6 3.2 8.3 0.2 15.4 16 1 0 16 16 16 3 Leucine rich repeat RA PF00788.18 KZN85325.1 - 2.8e-07 30.9 0.0 7.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.1 KZN85325.1 - 0.00014 21.5 8.9 0.75 9.5 0.1 4.6 3 2 1 4 4 4 2 Leucine rich repeats (6 copies) Ad_cyc_g-alpha PF08509.6 KZN85325.1 - 0.00074 18.8 0.1 0.0034 16.6 0.1 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 KZN85325.1 - 0.0052 16.7 48.2 12 6.2 0.1 14.7 15 1 1 16 16 16 2 Leucine Rich repeat Glyco_hydro_16 PF00722.16 KZN85326.1 - 5.6e-44 149.6 5.4 1e-43 148.7 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FRQ PF09421.5 KZN85327.1 - 0.0057 14.5 1.9 0.0073 14.1 1.3 1.1 1 0 0 1 1 1 1 Frequency clock protein RRN3 PF05327.6 KZN85327.1 - 0.32 9.0 4.4 0.79 7.7 1.7 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 KZN85327.1 - 0.87 8.8 10.5 1.1 8.4 7.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KZN85327.1 - 8.4 4.2 12.5 11 3.8 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KZN85327.1 - 9.1 5.8 10.5 13 5.3 7.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region ABC_membrane PF00664.18 KZN85328.1 - 2.7e-81 272.9 38.6 1.1e-42 146.3 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN85328.1 - 3.5e-72 241.1 0.0 9.5e-35 119.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KZN85328.1 - 2.2e-12 47.5 0.2 0.036 14.0 0.0 4.2 2 2 0 4 4 4 4 AAA domain SMC_N PF02463.14 KZN85328.1 - 2.7e-12 46.3 0.0 0.00096 18.4 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN85328.1 - 1.7e-08 34.6 2.2 0.0034 17.4 0.1 3.5 2 1 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KZN85328.1 - 7.5e-08 31.3 1.1 0.012 14.2 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KZN85328.1 - 3.7e-07 30.9 0.0 0.053 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN85328.1 - 4.9e-07 29.1 0.7 0.0056 16.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KZN85328.1 - 3.1e-06 26.4 0.0 0.086 12.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KZN85328.1 - 3.8e-05 23.9 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KZN85328.1 - 0.00013 21.8 0.1 2 8.3 0.0 3.7 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 KZN85328.1 - 0.00016 21.5 3.3 0.18 11.7 0.3 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 KZN85328.1 - 0.00018 20.9 0.5 0.14 11.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain PRK PF00485.13 KZN85328.1 - 0.00034 20.2 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 KZN85328.1 - 0.00041 20.5 1.5 4.4 7.5 0.1 4.6 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN85328.1 - 0.00053 19.7 0.2 2.2 7.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KZN85328.1 - 0.00056 19.4 2.3 1 8.8 0.7 3.1 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KZN85328.1 - 0.00056 19.5 2.2 3.8 7.0 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KZN85328.1 - 0.00084 19.4 3.8 2.5 8.2 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN85328.1 - 0.0015 18.4 0.3 2 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KZN85328.1 - 0.0018 18.1 0.5 0.59 9.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Mg_chelatase PF01078.16 KZN85328.1 - 0.0048 16.0 0.0 0.43 9.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KZN85328.1 - 0.0059 16.4 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KZN85328.1 - 0.0065 16.8 0.6 0.58 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN85328.1 - 0.012 15.7 0.0 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KZN85328.1 - 0.013 14.9 2.1 1.3 8.3 0.0 3.8 4 0 0 4 4 4 0 AAA-like domain MMR_HSR1 PF01926.18 KZN85328.1 - 0.014 15.3 0.0 3.8 7.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KZN85328.1 - 0.018 13.9 0.7 2.2 7.0 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 KZN85328.1 - 0.022 13.8 0.4 1.3 8.1 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin APS_kinase PF01583.15 KZN85328.1 - 0.047 13.3 0.6 13 5.4 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase Miro PF08477.8 KZN85328.1 - 0.06 13.8 0.0 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 KZN85328.1 - 0.068 12.2 0.0 0.7 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KZN85328.1 - 0.11 11.1 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.1 KZN85328.1 - 0.11 12.0 0.7 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KZN85328.1 - 0.18 10.9 1.5 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 KaiC Cys_Met_Meta_PP PF01053.15 KZN85329.1 - 8.2e-93 310.7 0.0 9.5e-93 310.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KZN85329.1 - 1.8e-06 26.9 0.0 2.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN85329.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KZN85329.1 - 0.081 11.2 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase FAD_oxidored PF12831.2 KZN85329.1 - 0.1 11.6 0.6 0.25 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase bZIP_1 PF00170.16 KZN85330.1 - 5e-05 23.1 0.8 0.00011 22.1 0.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KZN85330.1 - 0.12 11.9 0.1 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Aminotran_5 PF00266.14 KZN85331.1 - 1.7e-19 69.8 0.0 3.7e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN85331.1 - 0.00048 19.1 0.0 0.00096 18.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KZN85331.1 - 0.11 11.5 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fis1_TPR_C PF14853.1 KZN85332.1 - 5.6e-25 86.9 0.5 9e-25 86.3 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KZN85332.1 - 5.5e-16 57.5 0.0 8.4e-16 56.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KZN85332.1 - 0.011 15.5 1.4 0.011 15.5 1.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN85332.1 - 0.027 15.1 0.2 0.055 14.1 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF357 PF04010.8 KZN85332.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DdrB PF12747.2 KZN85332.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 DdrB-like protein Spc24 PF08286.6 KZN85333.1 - 2.6e-39 133.5 1.5 2e-38 130.6 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Streptin-Immun PF11083.3 KZN85333.1 - 0.013 15.4 0.4 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Prefoldin_2 PF01920.15 KZN85333.1 - 0.03 14.0 2.0 2.6 7.8 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit APG6 PF04111.7 KZN85333.1 - 0.12 11.4 4.9 0.14 11.1 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3166 PF11365.3 KZN85333.1 - 0.22 11.9 3.2 0.18 12.2 0.8 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3166) Viral_P18 PF04521.8 KZN85333.1 - 0.69 9.3 4.8 0.31 10.4 0.5 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DMPK_coil PF08826.5 KZN85333.1 - 1.2 9.0 8.7 0.69 9.8 0.6 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like Lge1 PF11488.3 KZN85333.1 - 5.6 7.2 7.2 2.3 8.4 0.4 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2034 PF10356.4 KZN85334.1 - 9.9e-43 145.4 0.0 3.4e-26 91.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KZN85334.1 - 3.1e-08 33.4 0.0 5.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.3 KZN85335.1 - 9.1e-58 194.3 6.1 7.5e-57 191.3 4.2 1.9 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 KZN85335.1 - 0.0015 18.1 3.2 0.037 13.7 2.5 2.5 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4515 PF14988.1 KZN85335.1 - 0.028 14.0 0.7 0.045 13.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) APG6 PF04111.7 KZN85335.1 - 0.036 13.1 0.6 0.053 12.5 0.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cortex-I_coil PF09304.5 KZN85335.1 - 0.05 13.6 2.4 0.081 12.9 1.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4455 PF14643.1 KZN85335.1 - 0.076 11.6 0.3 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Spore_III_AB PF09548.5 KZN85335.1 - 0.17 11.6 0.5 0.28 10.9 0.1 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FlgM PF04316.8 KZN85335.1 - 2.3 8.2 5.6 0.28 11.1 1.0 1.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM SNF2_N PF00176.18 KZN85336.1 - 5.8e-65 219.0 0.1 8.3e-65 218.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN85336.1 - 1.9e-09 37.2 0.1 1.1e-08 34.8 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN85336.1 - 3.1e-07 30.0 0.0 8.4e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KZN85336.1 - 0.0003 20.4 1.7 0.00051 19.7 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN85336.1 - 0.0062 16.3 2.8 0.013 15.2 2.0 1.6 1 0 0 1 1 1 1 Ring finger domain PI3_PI4_kinase PF00454.22 KZN85337.1 - 1.9e-36 125.7 0.0 2.8e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 KZN85338.1 - 7.6e-16 57.1 2.6 1.3e-15 56.3 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KZN85338.1 - 0.016 14.5 0.4 0.031 13.5 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.8 KZN85338.1 - 0.04 13.9 0.2 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein Pox_A_type_inc PF04508.7 KZN85338.1 - 0.12 12.2 0.4 0.12 12.2 0.3 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 KZN85338.1 - 0.13 12.0 4.7 7 6.5 1.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-F_N PF10481.4 KZN85338.1 - 0.14 11.4 2.1 1.3 8.2 1.2 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain ArfGap PF01412.13 KZN85338.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf bZIP_2 PF07716.10 KZN85338.1 - 1.1 9.1 8.2 10 6.0 0.1 2.5 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 KZN85338.1 - 1.1 8.7 3.9 1.7 8.2 2.7 1.2 1 0 0 1 1 1 0 IncA protein WD40_alt PF14077.1 KZN85338.1 - 2.6 7.7 5.9 9 6.0 0.1 3.2 2 1 1 3 3 3 0 Alternative WD40 repeat motif Nodulin-like PF06813.8 KZN85339.1 - 2.5e-24 85.8 0.8 5.3e-24 84.8 0.5 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 KZN85339.1 - 3.1e-15 55.7 29.0 3.1e-15 55.7 20.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Serinc PF03348.10 KZN85340.1 - 1.8e-174 580.4 13.5 2.1e-174 580.2 9.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PGA2 PF07543.7 KZN85340.1 - 0.5 10.1 2.9 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 MutL_C PF08676.6 KZN85341.1 - 2.5e-23 82.2 0.1 2.5e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KZN85341.1 - 2.7e-18 65.5 0.0 2.9e-17 62.2 0.0 2.7 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KZN85341.1 - 8.2e-14 51.4 0.0 3.6e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KZN85341.1 - 4.2e-12 45.7 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.8 KZN85342.1 - 3.3e-14 52.7 2.7 8.6e-14 51.4 2.1 1.4 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) APH PF01636.18 KZN85342.1 - 0.024 14.3 5.4 0.42 10.3 3.7 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.3 KZN85343.1 - 1e-62 211.9 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Sugar_tr PF00083.19 KZN85345.1 - 2.7e-92 309.7 18.9 3.3e-92 309.4 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85345.1 - 2.1e-27 95.7 44.6 2.6e-24 85.6 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN85345.1 - 0.0039 15.4 1.0 0.0039 15.4 0.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KZN85345.1 - 0.0041 15.2 3.0 0.01 13.9 1.7 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UPF0193 PF05250.6 KZN85346.1 - 0.059 12.9 0.7 0.067 12.7 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Mito_fiss_reg PF05308.6 KZN85347.1 - 0.0006 19.2 4.9 0.00082 18.8 3.4 1.3 1 0 0 1 1 1 1 Mitochondrial fission regulator NeA_P2 PF12312.3 KZN85347.1 - 4.6 6.3 9.5 2.3 7.3 5.6 1.3 1 1 0 1 1 1 0 Nepovirus subgroup A polyprotein Chitin_synth_2 PF03142.10 KZN85348.1 - 2.5e-250 831.3 1.1 3.7e-250 830.8 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KZN85348.1 - 2.6e-184 614.0 0.0 3.4e-184 613.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KZN85348.1 - 2.5e-18 65.6 0.0 2e-13 49.9 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KZN85348.1 - 1.4e-16 59.9 0.9 3.1e-15 55.6 0.6 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KZN85348.1 - 4.1e-12 46.3 0.0 3.6e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KZN85348.1 - 2.3e-11 43.7 9.0 2.3e-11 43.7 6.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KZN85348.1 - 0.0095 15.6 0.0 0.067 12.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KZN85348.1 - 0.018 14.2 0.0 0.071 12.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 AAA_16 PF13191.1 KZN85348.1 - 0.043 13.8 0.1 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KZN85348.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN85348.1 - 0.049 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KZN85348.1 - 0.17 12.1 0.0 0.54 10.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Chitin_synth_2 PF03142.10 KZN85349.1 - 2.7e-230 765.2 0.0 3.6e-230 764.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KZN85349.1 - 9.8e-74 248.6 0.0 2.6e-73 247.2 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KZN85349.1 - 8.3e-17 60.7 0.0 3.7e-08 33.0 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KZN85349.1 - 2.4e-16 60.0 3.3 2.4e-16 60.0 2.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KZN85349.1 - 1.5e-15 56.6 1.1 4.1e-15 55.2 0.6 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KZN85349.1 - 1e-13 51.6 0.0 8.7e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KZN85349.1 - 1.3e-05 24.5 0.0 5.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KZN85349.1 - 0.0029 17.3 0.0 0.04 13.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.1 KZN85349.1 - 0.044 13.7 2.0 3.8 7.5 0.2 2.6 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone Glyco_hydro_2_N PF02837.13 KZN85350.1 - 1.5e-27 96.2 0.0 3.6e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KZN85350.1 - 7.4e-14 51.3 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KZN85350.1 - 1.8e-07 31.5 0.0 4.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 KH_1 PF00013.24 KZN85351.1 - 1.1e-28 98.6 7.3 1e-07 31.4 0.2 7.5 9 0 0 9 9 9 5 KH domain KH_3 PF13014.1 KZN85351.1 - 3.5e-22 77.5 5.5 0.0003 20.3 0.0 6.2 6 0 0 6 6 6 4 KH domain HATPase_c_5 PF14501.1 KZN85351.1 - 0.077 12.7 1.1 0.18 11.5 0.2 2.0 1 1 1 2 2 2 0 GHKL domain HNH_2 PF13391.1 KZN85352.1 - 3.3e-06 26.7 0.2 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease HAD_2 PF13419.1 KZN85354.1 - 7e-27 94.7 0.0 8.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN85354.1 - 5.5e-07 30.2 0.0 6.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN85354.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PAH PF02671.16 KZN85354.1 - 0.14 11.8 0.8 0.57 9.8 0.2 2.1 2 0 0 2 2 2 0 Paired amphipathic helix repeat Dynactin PF12455.3 KZN85355.1 - 2.7e-91 305.3 11.1 2.7e-91 305.3 7.7 4.0 3 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 KZN85355.1 - 9e-23 79.7 0.2 1.6e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 KZN85355.1 - 0.0022 17.6 11.4 0.0022 17.6 7.9 8.0 3 2 2 5 5 5 1 IncA protein Reo_sigmaC PF04582.7 KZN85355.1 - 0.22 10.6 23.5 0.071 12.2 0.3 5.1 3 2 3 6 6 6 0 Reovirus sigma C capsid protein Solute_trans_a PF03619.11 KZN85357.1 - 2.5e-97 325.4 3.5 3e-97 325.2 2.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GntP_permease PF02447.11 KZN85358.1 - 2.7 6.3 0.1 17 3.7 0.0 1.9 2 0 0 2 2 2 0 GntP family permease Aminotran_1_2 PF00155.16 KZN85359.1 - 1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KZN85359.1 - 0.00055 18.6 0.0 0.0011 17.5 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 KZN85359.1 - 0.12 11.4 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family TPP_enzyme_N PF02776.13 KZN85360.1 - 8.2e-40 136.0 0.0 2.6e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN85360.1 - 2.1e-23 82.6 0.0 1.5e-22 79.8 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KZN85360.1 - 6.5e-21 74.4 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2235 PF09994.4 KZN85361.1 - 8.8e-69 231.9 0.0 1.2e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) APH PF01636.18 KZN85362.1 - 1.3e-05 25.0 0.2 2.4e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN85362.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PLDc_2 PF13091.1 KZN85363.1 - 9.3e-18 64.1 0.1 1.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KZN85363.1 - 0.021 14.6 0.2 0.46 10.3 0.0 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KZN85363.1 - 0.032 13.1 0.0 0.08 11.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB MmgE_PrpD PF03972.9 KZN85364.1 - 2.3e-99 332.5 0.0 2.8e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family BCDHK_Adom3 PF10436.4 KZN85365.1 - 3.8e-42 143.5 0.0 5.4e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KZN85365.1 - 1.4e-17 63.4 0.0 5.3e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KZN85365.1 - 0.16 11.7 0.0 0.58 9.9 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Inhibitor_I9 PF05922.11 KZN85366.1 - 9.7e-05 22.8 0.0 0.0001 22.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.5 KZN85367.1 - 1.6e-53 180.5 0.0 4.4e-53 179.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) DSPc PF00782.15 KZN85368.1 - 2.3e-21 75.7 0.0 6.1e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KZN85368.1 - 0.00094 18.5 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BDHCT PF08072.6 KZN85368.1 - 0.031 14.3 0.2 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain DUF663 PF04950.7 KZN85369.1 - 1.2e-92 310.0 0.3 1.2e-92 310.0 0.2 3.4 3 1 1 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KZN85369.1 - 1.3e-25 88.6 0.0 3.4e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KZN85369.1 - 8.1e-06 25.3 0.0 0.0019 17.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KZN85369.1 - 3e-05 24.1 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN85369.1 - 3.1e-05 24.0 0.2 0.0001 22.3 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 KZN85369.1 - 0.00029 21.1 0.6 0.001 19.3 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA_33 PF13671.1 KZN85369.1 - 0.00048 20.0 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN85369.1 - 0.0005 20.8 0.0 0.0005 20.8 0.0 4.8 3 1 0 3 3 1 1 AAA domain NACHT PF05729.7 KZN85369.1 - 0.00064 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 KZN85369.1 - 0.00065 19.4 0.2 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KZN85369.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN85369.1 - 0.0017 18.8 0.0 0.0058 17.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA PF00004.24 KZN85369.1 - 0.0028 17.8 0.0 0.0065 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KZN85369.1 - 0.0028 17.0 0.0 0.0099 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KZN85369.1 - 0.0046 16.5 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KZN85369.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN85369.1 - 0.0048 16.6 0.2 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain cobW PF02492.14 KZN85369.1 - 0.0076 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KZN85369.1 - 0.012 15.2 0.3 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KZN85369.1 - 0.013 14.3 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KZN85369.1 - 0.013 15.8 0.1 0.013 15.8 0.1 3.3 3 1 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 KZN85369.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 KZN85369.1 - 0.02 13.8 0.3 0.044 12.7 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain DUF258 PF03193.11 KZN85369.1 - 0.029 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KZN85369.1 - 0.034 13.6 0.1 0.28 10.6 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KZN85369.1 - 0.042 13.5 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 KZN85369.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.1 KZN85369.1 - 0.98 8.9 5.7 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KZN85372.1 - 4.3e-43 147.3 26.0 4.3e-43 147.3 18.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN85372.1 - 2.4e-09 35.9 1.0 2.4e-09 35.9 0.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN85372.1 - 1.5e-06 27.0 25.2 6.2e-06 25.0 17.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KZN85373.1 - 3e-16 59.0 0.0 4.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KZN85373.1 - 7.7e-08 32.2 8.6 4.4e-07 29.8 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KZN85373.1 - 2.4e-07 30.6 9.9 0.005 17.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN85373.1 - 1.3e-05 25.1 11.5 0.034 14.4 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Methyltransf_24 PF13578.1 KZN85374.1 - 2.3e-15 57.2 0.0 3.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KZN85374.1 - 1.7e-08 33.7 0.0 4.6e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KZN85374.1 - 2e-05 25.1 0.0 7.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF1442 PF07279.6 KZN85374.1 - 8.4e-05 21.7 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Sir1 PF11603.3 KZN85374.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Regulatory protein Sir1 Glyoxalase_2 PF12681.2 KZN85375.1 - 3.6e-15 56.4 0.0 1.3e-14 54.7 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KZN85375.1 - 1.3e-13 51.0 0.0 1.8e-12 47.3 0.0 2.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KZN85375.1 - 1.5e-06 28.2 0.0 3.7e-05 23.6 0.0 2.5 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PWI PF01480.12 KZN85376.1 - 9.6e-09 35.2 0.1 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_6 PF14259.1 KZN85376.1 - 3.9e-08 33.1 0.2 1.9e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85376.1 - 3.7e-07 29.8 0.0 9.6e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN85376.1 - 4.7e-07 29.3 0.3 6.2e-05 22.5 0.1 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN85376.1 - 2.2e-05 24.1 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KZN85376.1 - 0.011 15.3 1.8 0.021 14.5 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GRP PF07172.6 KZN85376.1 - 0.023 15.1 9.9 0.023 15.1 6.9 4.0 4 0 0 4 4 4 0 Glycine rich protein family Borrelia_P83 PF05262.6 KZN85376.1 - 1.6 6.9 12.4 2.3 6.4 8.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.1 KZN85376.1 - 2 7.3 14.7 3 6.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.22 KZN85377.1 - 9.1e-61 204.5 0.0 1.4e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KZN85377.1 - 1.4e-38 131.1 0.0 3.1e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KZN85377.1 - 3.4e-22 78.1 0.0 2e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 KZN85377.1 - 1.7e-12 47.0 0.0 4.3e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KZN85377.1 - 3.6e-11 43.0 0.1 4e-10 39.6 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN85377.1 - 8.3e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.11 KZN85378.1 - 1.7e-34 119.0 64.4 6.7e-30 103.9 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85378.1 - 0.0076 14.8 33.7 0.039 12.5 9.6 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1576 PF07613.6 KZN85378.1 - 0.88 9.0 8.5 0.21 11.0 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) Aminotran_4 PF01063.14 KZN85379.1 - 2.7e-27 95.7 0.0 3.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV HTH_Tnp_Tc5 PF03221.11 KZN85380.1 - 0.047 13.4 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 KZN85380.1 - 0.49 10.8 30.8 1 9.8 4.3 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger Pkinase PF00069.20 KZN85382.1 - 6.5e-58 195.9 0.0 8.8e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85382.1 - 8.3e-43 146.3 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN85382.1 - 3.4e-06 26.2 0.0 5.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN85382.1 - 0.0018 17.3 0.1 0.0047 16.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN85382.1 - 0.0032 17.2 0.1 0.017 14.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN85382.1 - 0.054 12.8 0.1 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KZN85385.1 - 7e-72 241.6 0.0 9.5e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85385.1 - 2.8e-36 124.9 0.0 4.2e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN85385.1 - 7.9e-05 21.7 0.0 0.00016 20.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KZN85385.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KZN85385.1 - 0.0064 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 KZN85386.1 - 5e-25 87.5 0.1 5.5e-25 87.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN85386.1 - 4.8e-07 29.5 0.0 5.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KZN85386.1 - 2.8e-05 23.9 0.1 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Aminotran_1_2 PF00155.16 KZN85387.1 - 1.1e-24 87.1 0.0 1.2e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KZN85387.1 - 0.14 10.6 0.0 0.3 9.5 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Surface_Ag_2 PF01617.12 KZN85387.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Surface antigen DUF3455 PF11937.3 KZN85388.1 - 1.2e-43 149.1 0.1 1.5e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.5 KZN85389.1 - 7.3e-25 87.7 0.0 1.6e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KZN85389.1 - 5.8e-16 58.5 4.6 0.017 15.3 0.0 7.6 6 3 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KZN85389.1 - 2e-10 39.8 10.1 0.46 10.7 0.2 8.9 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KZN85389.1 - 2.5e-10 40.5 3.0 0.75 10.3 0.0 7.8 7 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KZN85389.1 - 7.8e-06 26.1 0.7 1.1 9.7 0.0 4.9 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KZN85389.1 - 0.00084 19.2 0.2 18 5.1 0.0 4.4 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KZN85389.1 - 0.068 12.5 0.1 1.5 8.1 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal Podoplanin PF05808.6 KZN85389.1 - 0.074 12.6 0.9 0.2 11.2 0.6 1.7 1 0 0 1 1 1 0 Podoplanin zf-H2C2_2 PF13465.1 KZN85390.1 - 8.6e-12 44.7 14.5 5.9e-06 26.3 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KZN85390.1 - 6.2e-10 38.8 11.6 1.8e-05 24.7 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN85390.1 - 2.5e-07 30.5 8.3 0.00019 21.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KZN85390.1 - 5.7e-06 26.3 1.5 1.8e-05 24.7 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN85390.1 - 5.4e-05 23.2 5.7 0.00011 22.2 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN85390.1 - 0.00017 21.3 6.9 0.0037 17.1 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KZN85390.1 - 0.055 13.5 1.0 0.055 13.5 0.7 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KZN85390.1 - 0.69 9.7 5.1 0.24 11.1 0.5 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KZN85390.1 - 1.8 8.3 6.2 5.6 6.7 0.2 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 KZN85390.1 - 4.5 7.7 8.7 6.1 7.2 1.2 3.2 2 1 1 3 3 3 0 C2H2-type zinc-finger domain SNARE PF05739.14 KZN85391.1 - 0.00052 19.6 1.4 0.00052 19.6 0.9 2.3 2 0 0 2 2 2 1 SNARE domain PGC7_Stella PF15549.1 KZN85391.1 - 5.4 6.9 10.6 2.3 8.2 3.2 2.2 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain Sec1 PF00995.18 KZN85392.1 - 3.1e-129 432.2 0.0 3.5e-129 432.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Telomere_reg-2 PF10193.4 KZN85393.1 - 1.5e-32 112.2 0.0 4.6e-32 110.6 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Ebola_NP PF05505.7 KZN85393.1 - 0.0057 14.7 2.8 0.0089 14.1 2.0 1.2 1 0 0 1 1 1 1 Ebola nucleoprotein ThiF PF00899.16 KZN85394.1 - 5.2e-38 129.9 0.3 2.1e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KZN85394.1 - 2.6e-28 97.5 0.0 4.7e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KZN85394.1 - 2.8e-23 81.2 1.4 6.1e-23 80.1 1.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KZN85394.1 - 3.8e-13 48.6 3.4 3.8e-13 48.6 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KZN85394.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Cu-oxidase_2 PF07731.9 KZN85394.1 - 0.02 14.3 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Multicopper oxidase UBA_e1_C PF09358.5 KZN85394.1 - 0.04 14.0 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 KZN85394.1 - 0.087 12.7 0.4 0.18 11.6 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RNA_pol_A_bac PF01000.21 KZN85395.1 - 4.7e-28 97.5 0.0 9.4e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KZN85395.1 - 1.6e-13 49.5 0.0 2.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 KZN85396.1 - 1.4e-132 440.7 0.0 1.8e-132 440.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KZN85396.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Mito_carr PF00153.22 KZN85397.1 - 2.1e-46 155.5 0.0 1.4e-16 59.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 KZN85398.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KZN85399.1 - 0.032 13.9 0.1 0.079 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like SAP PF02037.22 KZN85400.1 - 2.7e-10 39.4 0.5 9e-10 37.8 0.0 2.1 2 0 0 2 2 2 1 SAP domain PorB PF11565.3 KZN85400.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Alpha helical Porin B Methyltransf_11 PF08241.7 KZN85401.1 - 0.0036 17.7 0.0 0.0083 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATP-synt_DE PF00401.15 KZN85401.1 - 0.025 14.4 0.5 0.058 13.2 0.4 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain p450 PF00067.17 KZN85402.1 - 6.8e-74 249.0 0.0 8.1e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Annexin PF00191.15 KZN85403.1 - 7.3e-61 201.9 0.5 5.6e-19 67.8 0.0 4.2 4 0 0 4 4 4 4 Annexin MFS_1 PF07690.11 KZN85406.1 - 1.2e-13 50.5 44.2 3.6e-12 45.6 29.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85406.1 - 0.0032 16.1 8.0 0.0032 16.1 5.5 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4405 PF14358.1 KZN85406.1 - 0.28 11.3 6.4 0.17 12.0 0.7 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) HCO3_cotransp PF00955.16 KZN85407.1 - 1.2e-53 182.5 15.4 1e-32 113.4 2.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF1955 PF09205.5 KZN85407.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) SET PF00856.23 KZN85408.1 - 3.3e-11 43.7 0.1 3.5e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 SET domain zf-C3HC4 PF00097.20 KZN85409.1 - 2.2e-08 33.5 5.3 2.2e-08 33.5 3.6 4.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN85409.1 - 1.8e-07 30.8 7.1 1.8e-07 30.8 5.0 4.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KZN85409.1 - 2.7e-07 30.4 6.4 2.7e-07 30.4 4.4 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 KZN85409.1 - 3.6e-07 29.6 0.4 3.6e-07 29.6 0.3 2.5 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_6 PF14835.1 KZN85409.1 - 3.5e-06 26.7 2.6 3.5e-06 26.7 1.8 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein ZZ PF00569.12 KZN85409.1 - 1.1e-05 24.8 5.5 1.1e-05 24.8 3.8 3.8 3 0 0 3 3 3 2 Zinc finger, ZZ type zf-C3HC4_4 PF15227.1 KZN85409.1 - 3.8e-05 23.4 6.5 3.8e-05 23.4 4.5 4.1 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN85409.1 - 0.00032 20.3 2.7 0.00032 20.3 1.9 2.8 3 0 0 3 3 3 1 RING-type zinc-finger SH3_2 PF07653.12 KZN85409.1 - 0.0079 15.6 0.2 0.024 14.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN85409.1 - 0.0088 15.4 0.3 0.02 14.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain CBM_21 PF03370.8 KZN85410.1 - 8.5e-37 125.5 0.8 1.5e-36 124.7 0.6 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 KZN85411.1 - 1.7e-15 56.8 0.3 2e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KZN85411.1 - 4.7e-05 23.4 0.1 6.4e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KZN85411.1 - 5.6e-05 23.1 0.2 9.5e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 KZN85411.1 - 6.1e-05 22.8 0.2 8.7e-05 22.3 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KZN85411.1 - 0.0037 16.9 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KZN85411.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 KZN85411.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PAD_porph PF04371.10 KZN85412.1 - 6.2e-65 219.4 0.0 7.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Fungal_trans_2 PF11951.3 KZN85413.1 - 3.4e-07 29.2 0.0 4.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85413.1 - 1.6 8.6 5.5 3 7.8 3.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 KZN85413.1 - 3.5 7.0 13.5 5.4 6.4 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acetyltransf_3 PF13302.1 KZN85414.1 - 3.9e-17 62.7 0.0 4.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN85414.1 - 5.2e-13 48.8 0.0 7.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KZN85414.1 - 6.5e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN85414.1 - 3.9e-07 30.0 0.0 9.4e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN85414.1 - 0.00046 20.3 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 KZN85415.1 - 5.3e-44 147.8 0.9 1.5e-15 56.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 KZN85415.1 - 0.02 15.2 0.7 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF346 PF03984.8 KZN85415.1 - 0.68 9.4 3.2 0.59 9.6 0.7 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) EBP PF05241.7 KZN85416.1 - 7.4e-69 230.6 5.4 9e-69 230.3 3.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3292 PF11696.3 KZN85418.1 - 3.5e-261 867.6 0.0 4e-261 867.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) ABM PF03992.11 KZN85419.1 - 0.00058 19.8 0.6 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Lin-8 PF03353.10 KZN85420.1 - 1.5 8.0 7.1 2.3 7.3 4.9 1.4 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist adh_short PF00106.20 KZN85421.1 - 3.1e-05 23.9 0.0 5.1e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Deltaretro_Tax PF05599.6 KZN85421.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Velvet PF11754.3 KZN85422.1 - 0.084 12.4 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Velvet factor L31 PF09784.4 KZN85424.1 - 2e-47 159.4 2.4 2.2e-47 159.3 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.16 KZN85425.1 - 1.3e-05 24.5 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DEAD PF00270.24 KZN85427.1 - 1.2e-41 142.0 0.9 2.5e-41 140.9 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN85427.1 - 1.1e-22 79.6 0.1 4.5e-12 45.6 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KZN85427.1 - 6.7e-07 29.3 1.1 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KZN85427.1 - 0.00098 17.2 0.1 0.0013 16.8 0.1 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_22 PF13401.1 KZN85427.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KZN85431.1 - 9.6e-28 97.1 0.1 1.6e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KZN85431.1 - 5.7e-27 94.2 29.8 9.6e-27 93.5 20.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 KZN85431.1 - 5.3e-07 29.8 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN85431.1 - 4.6e-06 26.7 0.0 7.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KZN85431.1 - 3.2e-05 23.8 0.1 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KZN85431.1 - 4.2e-05 22.7 0.0 7.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN85431.1 - 9.6e-05 21.8 0.0 0.0004 19.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KZN85431.1 - 0.00035 20.5 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KZN85431.1 - 0.00052 20.1 0.0 0.034 14.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 KZN85431.1 - 0.00065 20.5 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN85431.1 - 0.0015 18.7 0.1 0.0077 16.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KZN85431.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KZN85431.1 - 0.0017 18.4 0.1 0.0054 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KZN85431.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 KZN85431.1 - 0.0021 16.8 0.1 0.0035 16.1 0.1 1.2 1 0 0 1 1 1 1 ArgK protein Rad17 PF03215.10 KZN85431.1 - 0.0031 16.2 0.0 0.0046 15.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KZN85431.1 - 0.0033 16.9 0.0 0.009 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KZN85431.1 - 0.004 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KZN85431.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 KZN85431.1 - 0.0066 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KZN85431.1 - 0.007 15.6 0.1 0.029 13.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KZN85431.1 - 0.0089 15.1 0.0 0.7 8.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 KZN85431.1 - 0.01 15.4 0.3 0.029 13.9 0.2 1.6 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 KZN85431.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KZN85431.1 - 0.015 14.9 0.0 0.056 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KZN85431.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 KZN85431.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KZN85431.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KZN85431.1 - 0.034 14.0 0.0 0.084 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 KZN85431.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase SbcCD_C PF13558.1 KZN85431.1 - 0.047 13.6 0.2 0.63 9.9 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KZN85431.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KZN85431.1 - 0.051 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KZN85431.1 - 0.056 12.2 0.0 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain CHASE3 PF05227.8 KZN85431.1 - 0.12 12.0 0.4 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 CHASE3 domain SRP54 PF00448.17 KZN85431.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_35 PF14516.1 KZN85431.1 - 0.2 10.2 0.0 0.35 9.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain tRNA-synt_1d PF00750.14 KZN85432.1 - 2.4e-82 276.6 7.9 2.6e-45 154.8 3.8 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KZN85432.1 - 8.7e-28 96.6 0.3 2.4e-27 95.2 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KZN85432.1 - 6.3e-09 36.2 0.7 3.3e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Med9 PF07544.8 KZN85432.1 - 0.049 13.3 0.4 0.14 11.8 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FAD_binding_6 PF00970.19 KZN85433.1 - 1.5e-30 105.2 0.0 2.3e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KZN85433.1 - 4.1e-27 94.9 0.0 6.5e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KZN85433.1 - 5.7e-07 29.5 0.0 7.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KZN85433.1 - 0.00041 20.3 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3605 PF12239.3 KZN85434.1 - 7e-56 188.4 0.0 1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) HTH_27 PF13463.1 KZN85436.1 - 0.032 14.5 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Rrf2 PF02082.15 KZN85436.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_2 PF00891.13 KZN85437.1 - 5.3e-32 110.9 0.3 1.3e-30 106.3 0.0 2.0 2 0 0 2 2 2 2 O-methyltransferase SMC_N PF02463.14 KZN85438.1 - 2.3e-72 242.7 2.2 3.6e-72 242.1 1.5 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KZN85438.1 - 7.2e-33 113.1 0.0 4.9e-32 110.4 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KZN85438.1 - 7.8e-19 68.8 3.3 7.8e-19 68.8 2.3 6.6 2 2 1 4 4 2 1 AAA domain AAA_21 PF13304.1 KZN85438.1 - 5.8e-18 65.8 4.1 1.3e-09 38.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KZN85438.1 - 4.4e-10 39.1 22.3 1.9e-08 33.8 1.5 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KZN85438.1 - 0.00033 20.1 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 KZN85438.1 - 0.00094 18.3 9.5 0.00094 18.3 6.6 7.2 2 2 5 7 7 7 3 Autophagy protein Apg6 FliD_N PF02465.13 KZN85438.1 - 0.0036 17.6 2.4 0.0036 17.6 1.7 6.9 4 3 2 6 6 6 1 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 KZN85438.1 - 0.0039 16.4 28.1 0.1 11.7 1.1 5.3 2 2 3 6 6 6 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 KZN85438.1 - 0.055 11.9 84.3 0.022 13.2 8.4 6.4 3 2 3 7 7 7 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN85438.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.1 4 1 0 4 4 3 0 FtsK/SpoIIIE family IncA PF04156.9 KZN85438.1 - 2 7.9 105.0 0.31 10.6 6.7 6.9 3 2 3 6 6 6 0 IncA protein DUF2730 PF10805.3 KZN85438.1 - 9.9 5.9 28.5 4 7.2 0.1 7.3 5 1 2 7 7 7 0 Protein of unknown function (DUF2730) RIO1 PF01163.17 KZN85439.1 - 2.2e-72 242.3 0.1 2.2e-72 242.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KZN85439.1 - 7.3e-05 22.6 0.0 0.059 13.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN85439.1 - 0.0013 17.8 0.2 0.018 14.0 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG17 PF04108.7 KZN85440.1 - 1.5e-129 432.4 0.1 1.7e-129 432.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4358 PF14270.1 KZN85440.1 - 0.02 14.7 0.7 0.057 13.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) HR1 PF02185.11 KZN85440.1 - 0.047 13.4 0.6 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Hr1 repeat FliD_N PF02465.13 KZN85440.1 - 0.22 11.8 3.6 27 5.1 0.0 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1845 PF08900.6 KZN85440.1 - 0.96 8.6 5.1 0.33 10.2 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1845) Flu_NS2 PF00601.14 KZN85440.1 - 1.2 9.3 4.3 26 5.0 0.1 3.8 3 1 2 5 5 5 0 Influenza non-structural protein (NS2) Syntaxin-6_N PF09177.6 KZN85440.1 - 1.5 9.2 8.2 11 6.4 0.2 3.7 3 1 1 4 4 4 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.4 KZN85440.1 - 1.7 8.6 4.3 34 4.3 0.0 3.0 3 0 0 3 3 3 0 Zinc finger-containing protein DUF2293 PF10056.4 KZN85440.1 - 3.6 7.6 7.2 5.3 7.0 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) LXG PF04740.7 KZN85440.1 - 7.6 6.2 10.7 11 5.7 0.6 3.6 2 2 0 2 2 2 0 LXG domain of WXG superfamily WD40 PF00400.27 KZN85441.1 - 3.7e-51 169.2 13.9 7.5e-09 35.1 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KZN85441.1 - 1.5e-13 50.2 0.8 3.7e-13 48.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KZN85441.1 - 4.9e-12 44.7 11.0 0.018 13.1 0.2 5.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 KZN85441.1 - 7.9e-11 41.3 1.0 2.2e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 F-box domain UCH PF00443.24 KZN85444.1 - 1.8e-65 220.7 0.0 2.9e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN85444.1 - 5.7e-13 48.9 0.0 4.7e-06 26.2 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KZN85444.1 - 2e-09 37.7 0.0 1.2e-08 35.2 0.0 2.4 3 0 0 3 3 3 1 DUSP domain PX PF00787.19 KZN85446.1 - 1e-17 63.9 0.0 3.6e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KZN85446.1 - 2.1e-09 37.0 9.0 1.7e-05 24.1 1.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Noggin PF05806.7 KZN85446.1 - 0.084 12.1 0.0 0.44 9.7 0.0 1.9 2 0 0 2 2 2 0 Noggin Peptidase_C10 PF01640.12 KZN85446.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Peptidase C10 family Glyco_hydro_43 PF04616.9 KZN85447.1 - 1.2e-38 132.8 1.0 1.8e-38 132.3 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase PF00069.20 KZN85448.1 - 1e-06 28.0 0.0 4.5e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain DUF4407 PF14362.1 KZN85449.1 - 0.1 11.5 0.4 0.19 10.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2428 PF10350.4 KZN85450.1 - 1.8e-77 259.8 0.0 3e-77 259.1 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KZN85450.1 - 1.6e-08 33.9 8.9 0.55 10.4 0.2 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 KZN85450.1 - 2.6e-05 24.4 3.8 0.8 10.0 0.1 4.7 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KZN85450.1 - 0.017 15.6 8.5 1.2 9.7 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.18 KZN85450.1 - 0.029 14.1 0.1 1.7 8.5 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 KZN85450.1 - 0.086 11.0 0.0 0.2 9.8 0.0 1.5 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Tim17 PF02466.14 KZN85452.1 - 2e-27 95.7 4.1 2.4e-27 95.5 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fungal_trans_2 PF11951.3 KZN85453.1 - 6e-35 120.5 5.1 8.7e-35 120.0 3.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KZN85454.1 - 7.2e-47 159.7 0.0 1.5e-45 155.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85454.1 - 5.7e-26 91.1 0.0 9.3e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN85454.1 - 0.00044 19.2 0.0 0.0011 17.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Lipase_3 PF01764.20 KZN85455.1 - 2e-18 66.3 0.0 3.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FAD_binding_4 PF01565.18 KZN85456.1 - 1.9e-28 98.6 1.4 3.2e-28 97.9 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN85456.1 - 8.9e-14 51.1 0.0 2.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Acyltransferase PF01553.16 KZN85457.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase MFS_1 PF07690.11 KZN85458.1 - 9.6e-15 54.1 21.5 9.6e-15 54.1 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 KZN85458.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF202) RAI16-like PF10257.4 KZN85459.1 - 2.7e-87 292.9 0.0 4.1e-87 292.3 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.18 KZN85460.1 - 4.9e-16 58.5 2.0 8.2e-16 57.8 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KZN85460.1 - 2.8e-07 30.5 0.6 4.3e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.1 KZN85461.1 - 0.0013 18.3 11.9 0.0022 17.6 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KZN85461.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-C3HC4_2 PF13923.1 KZN85461.1 - 0.16 12.0 12.4 0.26 11.3 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KZN85461.1 - 1.5 8.6 6.6 2.6 7.9 4.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KZN85461.1 - 2.7 7.7 12.9 4.3 7.1 9.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF1900 PF08954.6 KZN85462.1 - 2.6e-51 172.7 0.0 6.1e-50 168.2 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KZN85462.1 - 2.4e-33 113.5 0.0 4.4e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KZN85462.1 - 6.7e-23 79.6 1.5 1.8e-06 27.5 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KZN85462.1 - 0.00012 20.4 0.2 0.21 9.6 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DivIC PF04977.10 KZN85462.1 - 0.057 12.9 1.5 0.12 11.8 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Apc4_WD40 PF12894.2 KZN85462.1 - 0.1 12.1 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SlyX PF04102.7 KZN85462.1 - 0.11 12.8 2.9 0.23 11.8 1.1 2.1 2 0 0 2 2 2 0 SlyX Kinesin PF00225.18 KZN85463.1 - 3.5e-105 351.4 0.8 3.5e-105 351.4 0.6 2.1 2 0 0 2 2 2 1 Kinesin motor domain Bac_DnaA PF00308.13 KZN85463.1 - 0.012 15.2 0.2 0.036 13.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein Arch_ATPase PF01637.13 KZN85463.1 - 0.027 14.1 4.4 1.9 8.1 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase ArsR PF09824.4 KZN85463.1 - 0.31 10.3 3.1 0.82 8.9 0.0 2.9 3 0 0 3 3 3 0 ArsR transcriptional regulator IF-2B PF01008.12 KZN85464.1 - 6.8e-19 67.9 0.0 1.3e-18 67.0 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KZN85464.1 - 1.2e-13 50.8 0.1 2.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF3631 PF12307.3 KZN85464.1 - 0.01 15.7 0.7 0.01 15.7 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) GFA PF04828.9 KZN85465.1 - 4.7e-18 64.9 0.2 6.3e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KZN85465.1 - 0.097 12.5 1.2 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.11 KZN85465.1 - 0.15 11.7 2.8 8.2 6.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 KZN85465.1 - 0.67 9.2 0.0 0.67 9.2 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain AAA_17 PF13207.1 KZN85466.1 - 1.4e-07 32.3 0.0 9.9e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN85466.1 - 3.6e-07 30.5 0.1 3.4e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KZN85466.1 - 7.3e-07 28.9 0.0 6.7e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KZN85466.1 - 2.6e-05 24.2 0.0 3.9e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KZN85466.1 - 6.3e-05 22.1 0.0 0.00093 18.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KZN85466.1 - 7.1e-05 22.7 0.0 0.00055 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KZN85466.1 - 0.00024 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.24 KZN85466.1 - 0.00059 20.0 0.0 0.00092 19.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KZN85466.1 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN85466.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KZN85466.1 - 0.0026 17.1 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.5 KZN85466.1 - 0.0031 16.7 0.0 0.0043 16.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MobB PF03205.9 KZN85466.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KZN85466.1 - 0.0055 15.6 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 KZN85466.1 - 0.0057 16.2 0.0 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KZN85466.1 - 0.0057 15.5 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ArgK PF03308.11 KZN85466.1 - 0.0079 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein FtsK_SpoIIIE PF01580.13 KZN85466.1 - 0.0098 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 KZN85466.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 KZN85466.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KZN85466.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.15 KZN85466.1 - 0.046 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 KZN85466.1 - 0.066 12.1 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KZN85466.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KZN85466.1 - 0.11 11.8 0.0 0.47 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 KZN85466.1 - 0.14 11.6 0.1 0.54 9.7 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Hemerythrin PF01814.18 KZN85467.1 - 9.9e-13 48.4 1.9 9.9e-13 48.4 1.3 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain RTA1 PF04479.8 KZN85468.1 - 7.4e-58 195.6 8.4 9.4e-58 195.3 5.8 1.0 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KZN85468.1 - 0.08 12.5 1.3 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Na_Ca_ex PF01699.19 KZN85469.1 - 1.9e-45 153.8 31.3 5.6e-23 81.1 8.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Fungal_trans PF04082.13 KZN85470.1 - 1.4e-22 79.8 0.0 2.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85470.1 - 5.2e-05 23.0 7.6 9.2e-05 22.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2397 PF09660.5 KZN85470.1 - 0.28 9.7 0.1 0.5 8.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF4401 PF14351.1 KZN85471.1 - 0.0025 16.8 18.7 0.053 12.4 13.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4401) DUF373 PF04123.8 KZN85471.1 - 0.0027 16.8 4.6 0.11 11.4 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF373) Cytochrom_B_C PF00032.12 KZN85471.1 - 0.047 13.9 6.1 0.12 12.6 1.3 2.9 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2614 PF11023.3 KZN85471.1 - 0.058 13.1 4.7 0.033 13.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Acyl_transf_3 PF01757.17 KZN85471.1 - 0.94 8.2 18.0 6.1 5.5 11.6 2.0 1 1 1 2 2 2 0 Acyltransferase family YjgP_YjgQ PF03739.9 KZN85471.1 - 3.9 6.1 16.2 0.16 10.6 3.7 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family PHD PF00628.24 KZN85472.1 - 7e-05 22.4 5.8 0.00013 21.5 4.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KZN85472.1 - 0.00061 19.0 1.6 0.0012 18.0 1.1 1.5 1 0 0 1 1 1 1 PHD-finger AA_permease PF00324.16 KZN85474.1 - 2.1e-129 431.9 46.4 2.6e-129 431.6 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN85474.1 - 3.4e-33 114.8 53.0 4.6e-33 114.3 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KZN85475.1 - 6.3e-22 77.7 32.3 6.2e-22 77.7 22.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85475.1 - 1.2e-05 24.0 10.0 1.2e-05 24.0 6.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85476.1 - 1.6e-38 132.3 25.5 1.6e-38 132.3 17.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85476.1 - 3.5e-12 45.6 13.4 3.5e-12 45.6 9.3 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter Fungal_trans PF04082.13 KZN85477.1 - 5.2e-22 77.9 2.8 8.6e-22 77.2 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_7N PF13733.1 KZN85477.1 - 0.11 11.9 0.1 7.4 5.9 0.0 2.5 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 Fungal_trans PF04082.13 KZN85478.1 - 1.6e-08 33.7 0.4 8.2e-08 31.4 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85479.1 - 2.4e-08 33.7 13.6 3.7e-08 33.1 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Siva PF05458.7 KZN85479.1 - 0.63 9.5 7.8 1 8.9 5.4 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF3608 PF12257.3 KZN85480.1 - 2e-74 250.0 0.0 3.5e-74 249.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KZN85480.1 - 4.1e-29 100.1 1.0 7.8e-29 99.2 0.7 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_18 PF12847.2 KZN85481.1 - 2.4e-12 47.4 0.0 3.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85481.1 - 1.8e-10 40.6 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85481.1 - 3.3e-10 40.3 0.0 5.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN85481.1 - 3e-08 33.5 0.0 3.7e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN85481.1 - 4.9e-08 33.3 0.0 7.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KZN85481.1 - 7.1e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.1 KZN85481.1 - 0.00031 21.0 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN85481.1 - 0.0019 18.2 0.1 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KZN85481.1 - 0.0038 16.7 0.0 0.0082 15.6 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 KZN85481.1 - 0.0047 16.0 0.1 0.01 14.9 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KZN85481.1 - 0.0066 15.8 0.1 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Glyco_hydro_31 PF01055.21 KZN85482.1 - 3.7e-122 408.3 0.7 4.9e-122 407.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN85482.1 - 1e-21 76.5 0.0 4.9e-20 71.1 0.1 3.0 2 0 0 2 2 2 1 Galactose mutarotase-like Glyoxalase_5 PF14696.1 KZN85482.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal FNIP_N PF14636.1 KZN85483.1 - 1.5e-20 73.9 0.0 1.5e-20 73.9 0.0 4.2 2 1 1 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KZN85483.1 - 0.22 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain NUC153 PF08159.7 KZN85484.1 - 2.7e-11 42.8 7.3 5.4e-10 38.6 0.2 4.0 3 0 0 3 3 3 2 NUC153 domain Eaf7 PF07904.8 KZN85484.1 - 0.14 12.1 5.7 0.26 11.2 1.3 3.1 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 PRK PF00485.13 KZN85485.1 - 7.5e-57 192.0 0.0 1.1e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KZN85485.1 - 2.6e-40 137.8 0.0 4.8e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KZN85485.1 - 5.7e-09 36.8 0.0 1.6e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN85485.1 - 2.9e-06 27.6 0.1 1.9e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain CPT PF07931.7 KZN85485.1 - 5.7e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KZN85485.1 - 0.0061 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 KZN85485.1 - 0.0062 16.2 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Zeta_toxin PF06414.7 KZN85485.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 KZN85485.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KZN85485.1 - 0.042 13.5 0.4 0.72 9.5 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 KZN85485.1 - 0.12 12.2 0.2 0.5 10.2 0.1 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family NB-ARC PF00931.17 KZN85485.1 - 0.13 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KZN85485.1 - 0.13 12.5 0.3 0.45 10.8 0.1 1.9 2 0 0 2 2 2 0 ABC transporter CLTH PF10607.4 KZN85486.1 - 8.5e-34 116.3 0.1 1.1e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KZN85486.1 - 1.3e-09 37.5 0.0 2.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 LisH RPAP3_C PF13877.1 KZN85486.1 - 0.016 15.1 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 ATP-cone PF03477.11 KZN85486.1 - 0.18 12.2 2.2 3.3 8.2 0.0 3.4 2 2 1 3 3 3 0 ATP cone domain Pyr_redox_2 PF07992.9 KZN85488.1 - 1.2e-20 74.2 0.0 2.3e-20 73.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN85488.1 - 4.2e-14 52.7 0.0 5.5e-12 45.9 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KZN85488.1 - 7.2e-06 26.0 0.1 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KZN85488.1 - 1.2e-05 24.2 0.1 4.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KZN85488.1 - 0.00015 21.3 0.1 0.0005 19.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KZN85488.1 - 0.00049 19.3 0.1 0.0029 16.8 0.0 2.2 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 KZN85488.1 - 0.077 13.0 0.1 5.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nipped-B_C PF12830.2 KZN85489.1 - 1.2e-50 171.7 0.6 1.2e-50 171.7 0.4 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KZN85489.1 - 5.9e-13 48.4 0.9 2.8e-12 46.2 0.2 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KZN85489.1 - 0.00082 19.2 4.1 0.019 14.7 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MA3 PF02847.12 KZN85489.1 - 0.0024 17.5 0.1 2.4 7.9 0.0 3.8 3 0 0 3 3 3 2 MA3 domain HEAT PF02985.17 KZN85489.1 - 0.4 10.8 6.2 3.4 7.9 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat TFIIS_C PF01096.13 KZN85490.1 - 2e-12 46.5 3.3 2e-12 46.5 2.3 3.2 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KZN85490.1 - 5.3e-06 26.0 3.3 2.6e-05 23.8 0.4 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 KZN85490.1 - 0.0005 19.4 5.1 0.042 13.3 0.1 2.8 3 1 0 3 3 3 2 zinc-ribbon domain DZR PF12773.2 KZN85490.1 - 0.00071 19.3 3.1 0.029 14.1 0.2 2.5 2 0 0 2 2 2 1 Double zinc ribbon Zn_ribbon_recom PF13408.1 KZN85490.1 - 0.0047 17.1 5.4 0.21 11.8 0.1 2.4 2 1 0 2 2 2 2 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 KZN85490.1 - 0.023 14.0 3.7 3.7 6.9 0.1 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding DUF2072 PF09845.4 KZN85490.1 - 0.026 14.4 2.3 0.73 9.7 0.1 2.1 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) Zn-ribbon_8 PF09723.5 KZN85490.1 - 0.031 14.2 1.2 1.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain C1_1 PF00130.17 KZN85490.1 - 0.069 12.8 2.7 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 KZN85490.1 - 0.082 12.7 2.1 1.1 9.2 0.1 2.4 3 0 0 3 3 3 0 IBR domain zf-trcl PF13451.1 KZN85490.1 - 0.13 11.9 5.4 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain YhfH PF14149.1 KZN85490.1 - 0.15 11.8 3.3 11 5.8 0.1 3.0 3 0 0 3 3 3 0 YhfH-like protein zf-ribbon_3 PF13248.1 KZN85490.1 - 0.19 10.9 7.3 2.9 7.1 0.0 3.4 3 1 1 4 4 4 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 KZN85490.1 - 0.41 10.2 3.4 4 7.0 0.0 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 OrfB_Zn_ribbon PF07282.6 KZN85490.1 - 0.43 10.2 9.4 0.39 10.3 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 KZN85490.1 - 0.53 10.0 9.8 8.1 6.2 0.0 3.5 4 0 0 4 4 3 0 Nudix N-terminal RNHCP PF12647.2 KZN85490.1 - 0.83 9.5 5.3 3.5 7.5 2.5 2.5 1 1 1 2 2 2 0 RNHCP domain Elf1 PF05129.8 KZN85490.1 - 1.1 8.9 5.4 2.9 7.6 0.5 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like HEAT_2 PF13646.1 KZN85491.1 - 5.2e-29 100.3 1.0 2.4e-15 56.5 0.0 3.5 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 KZN85491.1 - 2e-16 58.7 0.1 0.012 15.9 0.1 6.5 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KZN85491.1 - 1.7e-09 36.9 0.5 1.9 8.8 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KZN85491.1 - 1.5e-07 31.6 3.0 0.17 12.3 0.0 4.6 3 2 2 5 5 5 4 HEAT-like repeat Cohesin_HEAT PF12765.2 KZN85491.1 - 0.055 13.4 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.8 KZN85491.1 - 0.062 13.4 3.9 3.8 7.7 0.1 3.2 4 0 0 4 4 4 0 RuvA, C-terminal domain ETC_C1_NDUFA4 PF04800.7 KZN85492.1 - 6.6e-38 128.6 0.6 1.1e-37 127.9 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 KZN85492.1 - 0.067 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) F1F0-ATPsyn_F PF10791.4 KZN85493.1 - 1.6e-35 121.1 1.0 1.3e-33 115.0 0.7 2.0 1 1 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KZN85493.1 - 0.0018 18.2 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f MOZ_SAS PF01853.13 KZN85495.1 - 4.6e-85 283.6 0.1 6.5e-85 283.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KZN85495.1 - 1.6e-23 82.1 0.0 3.4e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KZN85495.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4484 PF14831.1 KZN85495.1 - 0.1 12.6 0.4 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) mRNA_cap_enzyme PF01331.14 KZN85496.1 - 2.6e-53 180.5 0.1 3.7e-53 180.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KZN85496.1 - 2.2e-23 82.5 0.0 3.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KZN85496.1 - 5.4e-08 32.4 0.2 2.3e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SCA7 PF08313.7 KZN85497.1 - 2e-33 113.7 3.3 8.1e-33 111.8 2.3 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.9 KZN85497.1 - 0.42 8.5 10.6 0.59 8.0 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.21 KZN85498.1 - 3.9e-43 147.7 0.6 3.9e-43 147.7 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KZN85498.1 - 6.9e-33 113.0 4.1 1.8e-32 111.6 2.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KZN85498.1 - 6.9e-06 25.2 0.7 4e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN85498.1 - 0.00098 18.5 3.7 0.014 14.8 0.4 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain Arginase PF00491.16 KZN85499.1 - 6.3e-92 307.7 0.0 7.4e-92 307.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KZN85499.1 - 0.00031 20.9 0.2 0.00073 19.7 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain DUF1301 PF06979.7 KZN85499.1 - 0.15 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) Ras PF00071.17 KZN85500.1 - 3.6e-52 176.0 0.0 4.2e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN85500.1 - 6.2e-16 58.9 0.0 9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN85500.1 - 6.4e-06 25.5 0.0 8.9e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 KZN85501.1 - 1.2e-19 70.3 44.2 7e-19 67.7 29.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN85501.1 - 0.0034 17.1 4.1 0.0034 17.1 2.8 2.6 2 0 0 2 2 2 1 MFS_1 like family DUF1349 PF07081.6 KZN85502.1 - 2.7e-23 82.2 0.0 3.3e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CAP59_mtransfer PF11735.3 KZN85503.1 - 4e-83 278.3 0.0 5.2e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 KZN85504.1 - 4.6e-58 196.8 0.0 9.8e-58 195.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF2092 PF09865.4 KZN85505.1 - 0.062 12.3 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF1762 PF08574.5 KZN85507.1 - 1.9e-19 69.8 13.8 1.9e-19 69.8 9.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) RRM_6 PF14259.1 KZN85508.1 - 2e-38 130.1 0.0 1.8e-10 40.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN85508.1 - 1.8e-37 126.8 0.0 1.7e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85508.1 - 1e-16 60.4 0.0 0.0015 18.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KZN85508.1 - 9.1e-15 53.9 3.4 4e-14 51.9 2.3 2.2 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 KZN85508.1 - 1.6e-05 24.6 0.1 0.082 12.7 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 KZN85508.1 - 0.021 14.7 0.0 1.8 8.5 0.0 3.2 3 1 0 3 3 3 0 RNA binding domain tRNA-synt_2 PF00152.15 KZN85509.1 - 6.1e-71 238.9 0.0 9.7e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN85509.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MAD PF05557.8 KZN85509.1 - 0.0084 14.2 1.2 0.012 13.7 0.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Bcl-2_BAD PF10514.4 KZN85511.1 - 0.036 14.0 3.1 2 8.3 0.2 2.2 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD Ecl1 PF12855.2 KZN85512.1 - 2.4e-14 52.3 3.9 4e-14 51.6 2.7 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KZN85512.1 - 0.0022 17.2 1.4 0.005 16.1 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 KZN85512.1 - 0.041 13.7 1.7 0.096 12.5 1.2 1.6 1 0 0 1 1 1 0 MYND finger YL1 PF05764.8 KZN85513.1 - 1.4e-57 195.0 21.6 1.4e-57 195.0 15.0 2.4 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 KZN85513.1 - 6.5e-12 44.7 0.3 6.5e-12 44.7 0.2 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 KZN85514.1 - 5.2e-29 98.0 0.0 5.1e-05 22.5 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KZN85514.1 - 5.1e-10 38.8 0.0 1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85514.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN85514.1 - 4e-05 23.5 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 KZN85515.1 - 2.6e-40 138.2 50.0 1.1e-39 136.1 33.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2768 PF10966.3 KZN85515.1 - 0.03 14.4 6.8 0.04 14.0 1.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Peptidase_C12 PF01088.16 KZN85516.1 - 3.9e-62 209.2 0.0 4.6e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 KZN85516.1 - 0.035 14.6 0.1 0.22 12.1 0.0 2.1 1 1 1 2 2 2 0 Glyoxalase-like domain Adeno_E3B PF03376.9 KZN85517.1 - 9.3 6.2 11.6 0.14 12.1 1.7 2.7 2 1 0 2 2 2 0 Adenovirus E3B protein DcpS PF05652.7 KZN85518.1 - 6.3e-29 100.5 0.0 1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 KZN85518.1 - 8.6e-28 96.8 0.0 1.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNase_H2_suC PF08615.6 KZN85519.1 - 3e-31 108.0 0.0 3.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Glyco_hydro_76 PF03663.9 KZN85519.1 - 0.053 12.9 0.2 0.072 12.4 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 RNase_T PF00929.19 KZN85520.1 - 6.7e-29 101.2 0.0 1.1e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Nop53 PF07767.6 KZN85521.1 - 1e-114 383.5 30.5 1.2e-114 383.3 21.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FLO_LFY PF01698.11 KZN85521.1 - 0.076 11.8 13.3 0.14 10.9 9.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Myb_Cef PF11831.3 KZN85522.1 - 4.5e-66 222.3 1.2 4.5e-66 222.3 0.8 3.5 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KZN85522.1 - 5.3e-20 71.2 5.4 2.3e-09 37.1 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KZN85522.1 - 8.7e-20 70.5 4.8 2.7e-13 49.8 0.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ribophorin_I PF04597.9 KZN85523.1 - 1.1e-150 502.0 0.0 1.2e-150 501.8 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I DUF2502 PF10697.4 KZN85523.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) Indigoidine_A PF04227.7 KZN85524.1 - 3.1e-111 371.2 0.3 4.3e-111 370.8 0.2 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KZN85524.1 - 6.6e-15 55.0 0.1 3.8e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Arrestin_N PF00339.24 KZN85525.1 - 4.9e-06 26.4 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SnoaL PF07366.7 KZN85526.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase RGS-like PF09128.6 KZN85526.1 - 0.08 12.4 1.3 0.19 11.2 0.9 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Flavokinase PF01687.12 KZN85527.1 - 1.9e-35 121.4 0.0 2.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 KZN85528.1 - 0.0068 16.2 9.2 0.014 15.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KZN85528.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold MFS_1 PF07690.11 KZN85529.1 - 7.7e-39 133.3 30.6 9.5e-39 133.0 21.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN85529.1 - 4.9e-06 25.0 2.5 4.9e-06 25.0 1.7 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KZN85529.1 - 0.0017 16.5 2.5 0.0023 16.1 1.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Bap31 PF05529.7 KZN85529.1 - 0.036 13.5 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1049 PF06305.6 KZN85529.1 - 2.6 7.5 0.0 2.6 7.5 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1049) Rad21_Rec8_N PF04825.8 KZN85530.1 - 1e-38 131.6 0.0 2.1e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KZN85530.1 - 4.2e-07 29.0 0.8 9.3e-07 27.9 0.2 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KZN85530.1 - 0.09 12.3 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 ScpA/B protein E1-E2_ATPase PF00122.15 KZN85531.1 - 8.1e-83 276.9 0.1 1.4e-82 276.1 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN85531.1 - 1.7e-43 148.3 0.2 1.7e-43 148.3 0.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN85531.1 - 8.1e-30 104.8 0.0 5.8e-29 102.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN85531.1 - 3e-20 71.4 0.0 5.9e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KZN85531.1 - 9.7e-15 55.2 0.0 2.6e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN85531.1 - 6.5e-14 51.6 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN85531.1 - 1.5e-05 24.7 1.2 0.00013 21.6 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KZN85532.1 - 3.5e-17 62.3 0.0 3.4e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85532.1 - 2.4e-13 49.7 0.0 8.4e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN85532.1 - 0.0026 16.8 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN85532.1 - 0.062 12.2 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 KZN85532.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KZN85532.1 - 0.085 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ammonium_transp PF00909.16 KZN85534.1 - 3.5e-115 384.6 29.1 4.1e-115 384.4 20.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.7 KZN85535.1 - 2.2e-107 358.6 0.0 3.2e-107 358.1 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein TMF_TATA_bd PF12325.3 KZN85535.1 - 0.19 11.4 0.4 11 5.7 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SIR2 PF02146.12 KZN85536.1 - 1.1e-57 194.6 0.0 1.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 KZN85536.1 - 0.29 11.1 3.0 0.65 10.0 2.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Hexokinase_2 PF03727.11 KZN85537.1 - 1e-86 290.1 0.0 1.3e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KZN85537.1 - 1.5e-75 253.0 0.0 2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 KZN85537.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PHO4 PF01384.15 KZN85540.1 - 1e-109 366.1 14.6 1.2e-109 365.8 10.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF1929 PF09118.6 KZN85541.1 - 9.4e-19 67.3 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KZN85541.1 - 1.6e-14 53.3 4.6 3.7e-05 23.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KZN85541.1 - 2.4e-08 33.4 4.3 0.037 13.7 0.2 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 KZN85541.1 - 3.3e-08 32.9 1.7 0.00061 19.2 0.1 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 KZN85541.1 - 7.6e-06 25.8 5.7 0.9 9.8 0.2 5.1 5 0 0 5 5 5 3 Kelch motif Glyoxal_oxid_N PF07250.6 KZN85541.1 - 1.9e-05 23.8 0.1 0.082 11.9 0.0 2.7 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_5 PF13854.1 KZN85541.1 - 0.0017 18.2 2.2 2.5 8.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Cu-oxidase_3 PF07732.10 KZN85542.1 - 7.8e-40 135.2 0.6 2.5e-39 133.6 0.2 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN85542.1 - 4.7e-26 90.9 1.6 8.8e-23 80.3 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KZN85542.1 - 5.7e-19 68.5 0.0 4.4e-17 62.4 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN85543.1 - 4.8e-38 129.5 4.5 4.8e-38 129.5 3.1 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN85543.1 - 1.7e-37 127.9 0.8 1.7e-37 127.9 0.5 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KZN85543.1 - 3.4e-37 127.7 0.9 1.2e-34 119.4 0.2 2.7 2 0 0 2 2 2 2 Multicopper oxidase MRP-S35 PF10246.4 KZN85543.1 - 0.21 11.5 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Cupin_8 PF13621.1 KZN85546.1 - 1.4e-09 37.8 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.24 KZN85546.1 - 3.9e-09 36.0 5.8 3.9e-09 36.0 4.1 2.6 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.17 KZN85546.1 - 5.5e-09 36.2 0.1 5.1e-08 33.1 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD_2 PF13831.1 KZN85546.1 - 0.00031 20.0 4.8 0.00033 19.8 1.9 2.3 2 0 0 2 2 2 1 PHD-finger Dickkopf_N PF04706.7 KZN85546.1 - 0.17 12.0 9.5 3.9 7.7 1.8 2.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KZN85546.1 - 2.5 8.0 30.5 0.26 11.2 4.4 3.5 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 KZN85547.1 - 3.5e-19 68.2 0.3 5.7e-19 67.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN85547.1 - 1.3e-13 50.7 0.1 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85547.1 - 1.8e-10 40.5 0.1 2.9e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPCD PF14913.1 KZN85547.1 - 0.074 12.1 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 DPCD protein family RRM_3 PF08777.6 KZN85547.1 - 0.083 12.7 0.2 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif DUF3661 PF12400.3 KZN85548.1 - 1.9e-42 144.3 4.4 3.2e-42 143.6 3.1 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein WD40 PF00400.27 KZN85549.1 - 3.8e-09 36.0 0.8 0.062 13.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF946 PF06101.6 KZN85550.1 - 1.6e-12 46.2 3.3 1.8e-12 46.0 0.6 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KZN85550.1 - 0.02 14.6 0.2 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) TFIIIC_sub6 PF10419.4 KZN85551.1 - 4e-14 51.7 0.1 8.3e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 TFIIIC subunit Mito_fiss_reg PF05308.6 KZN85552.1 - 0.74 9.1 3.7 0.82 8.9 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator ELFV_dehydrog PF00208.16 KZN85553.1 - 3.6e-58 197.0 0.0 5.7e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KZN85553.1 - 5.7e-18 63.8 0.0 1.1e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Sporozoite_P67 PF05642.6 KZN85554.1 - 0.005 14.7 7.5 0.0069 14.3 5.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Tub_2 PF04525.7 KZN85554.1 - 0.18 11.1 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Tubby C 2 DUF1212 PF06738.7 KZN85555.1 - 2.1e-56 190.4 8.4 5.2e-48 163.0 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KZN85555.1 - 5.3e-26 91.0 9.4 5.3e-26 91.0 6.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) MFS_1 PF07690.11 KZN85558.1 - 7.8e-31 107.0 49.3 7.8e-31 107.0 34.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KZN85559.1 - 2.5e-18 66.5 0.4 1.5e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KZN85559.1 - 4.5e-06 26.2 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KZN85559.1 - 3.5e-05 23.6 0.0 0.0036 17.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN85559.1 - 4.7e-05 23.1 0.0 7.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KZN85559.1 - 0.00087 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein zf-ribbon_3 PF13248.1 KZN85560.1 - 0.00042 19.4 4.3 0.00099 18.2 3.0 1.7 1 0 0 1 1 1 1 zinc-ribbon domain CD20 PF04103.10 KZN85560.1 - 0.0022 17.9 0.9 0.0035 17.2 0.3 1.5 2 0 0 2 2 2 1 CD20-like family DZR PF12773.2 KZN85560.1 - 0.003 17.3 3.1 0.0065 16.2 2.1 1.6 1 0 0 1 1 1 1 Double zinc ribbon DUF161 PF02588.10 KZN85560.1 - 0.0072 16.6 0.0 0.0095 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized BCR, YitT family COG1284 EphA2_TM PF14575.1 KZN85560.1 - 0.0072 16.6 0.1 0.024 15.0 0.1 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KZN85560.1 - 0.0075 16.4 1.3 0.0075 16.4 0.9 2.6 2 1 2 4 4 2 1 Wnt and FGF inhibitory regulator MSC PF09402.5 KZN85560.1 - 0.009 14.7 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RRN7 PF11781.3 KZN85560.1 - 0.019 14.4 8.2 0.5 9.8 0.9 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_2 PF13240.1 KZN85560.1 - 0.027 13.9 8.1 0.3 10.6 5.4 2.4 1 1 1 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KZN85560.1 - 0.077 12.6 8.1 0.32 10.7 0.5 2.5 1 1 1 2 2 2 0 Nudix N-terminal DUF1517 PF07466.6 KZN85560.1 - 0.14 11.0 0.6 0.22 10.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) Claudin_2 PF13903.1 KZN85560.1 - 0.2 11.3 3.8 0.34 10.5 2.0 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 KZN85560.1 - 0.31 10.8 2.9 6.1 6.6 2.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1218 PF06749.7 KZN85560.1 - 0.53 10.7 6.0 0.096 13.1 0.4 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF1218) DUF1469 PF07332.6 KZN85560.1 - 1.4 8.6 5.1 3.6 7.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) zf-NADH-PPase PF09297.6 KZN85560.1 - 2.3 7.8 8.8 2.3 7.8 1.6 2.4 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1772 PF08592.6 KZN85561.1 - 0.099 12.3 4.4 0.14 11.8 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) eIF3g PF12353.3 KZN85563.1 - 0.032 14.1 2.4 0.069 13.0 1.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Acyl_transf_1 PF00698.16 KZN85564.1 - 4.4e-100 335.0 0.0 6.7e-100 334.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KZN85564.1 - 6.7e-85 284.5 0.8 1.1e-84 283.8 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN85564.1 - 4.9e-58 195.7 0.0 1.2e-57 194.5 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KZN85564.1 - 1.3e-49 168.2 0.0 3.3e-49 167.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN85564.1 - 3.6e-43 146.2 2.6 4.1e-43 146.0 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KZN85564.1 - 1.8e-15 56.9 0.3 3.6e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KZN85564.1 - 2.7e-11 43.5 0.0 7.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN85564.1 - 2e-05 23.7 1.6 2.2e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Cupin_2 PF07883.6 KZN85565.1 - 0.00054 19.3 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Cupin domain p450 PF00067.17 KZN85566.1 - 2.8e-79 266.7 0.0 3.5e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KZN85567.1 - 6.7e-20 71.0 3.0 1.1e-19 70.3 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85567.1 - 2.2e-07 30.6 10.6 6e-07 29.2 7.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KZN85567.1 - 0.0054 16.3 0.8 0.022 14.5 0.5 2.1 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Amidohydro_2 PF04909.9 KZN85568.1 - 8.2e-23 81.3 0.6 9.6e-23 81.1 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 KZN85569.1 - 2.1e-76 257.3 0.0 2.6e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YkyB PF14177.1 KZN85569.1 - 0.048 13.8 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 YkyB-like protein PPR_2 PF13041.1 KZN85570.1 - 1.5e-09 37.6 0.4 2.7 8.0 0.0 7.6 7 2 2 9 9 9 2 PPR repeat family PPR_3 PF13812.1 KZN85570.1 - 2.8e-09 36.5 2.0 0.09 13.0 0.0 7.2 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KZN85570.1 - 5.5e-05 22.8 4.4 0.31 11.0 0.2 6.6 7 0 0 7 7 7 1 PPR repeat TPR_19 PF14559.1 KZN85570.1 - 0.0033 17.7 4.4 1.5 9.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Death_2 PF14786.1 KZN85570.1 - 0.055 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Tube Death domain Mycoplasma_p37 PF06646.6 KZN85570.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 High affinity transport system protein p37 Ribosomal_S18 PF01084.15 KZN85571.1 - 1.5e-14 53.5 0.0 3.8e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S18 WD40 PF00400.27 KZN85572.1 - 8.8e-22 76.1 13.3 1.8e-07 30.7 1.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat DUF126 PF01989.11 KZN85572.1 - 0.097 12.3 0.1 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF126 FUSC_2 PF13515.1 KZN85573.1 - 2.2e-28 98.7 9.3 2.2e-28 98.7 6.4 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KZN85573.1 - 6.3e-06 25.9 0.4 1.4e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KZN85573.1 - 0.00025 19.8 20.2 0.038 12.6 0.0 3.9 4 1 0 4 4 4 2 Aluminium activated malate transporter WHIM1 PF15612.1 KZN85573.1 - 0.084 12.8 0.1 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Rota_NSP3 PF01665.11 KZN85573.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 SAGA-Tad1 PF12767.2 KZN85574.1 - 1.6e-57 195.0 0.0 2e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 KZN85575.1 - 8.5e-53 178.2 6.6 2.7e-52 176.5 4.5 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KZN85575.1 - 1.1e-30 103.2 37.4 5.9e-05 23.3 0.3 14.6 5 3 10 15 15 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 KZN85575.1 - 1.5e-28 98.8 14.3 1.2e-06 28.7 0.2 9.7 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KZN85575.1 - 3.9e-27 94.2 24.5 9.5e-06 26.1 1.2 8.6 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KZN85575.1 - 1.4e-13 50.2 10.7 0.0027 17.3 0.0 8.5 5 4 5 10 10 10 5 TPR repeat TPR_2 PF07719.12 KZN85575.1 - 5.6e-13 47.7 12.4 0.38 10.7 0.0 9.0 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KZN85575.1 - 1.1e-07 31.1 0.6 0.54 9.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 KZN85575.1 - 4.5e-07 29.2 20.7 0.00026 20.1 4.8 5.5 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN85575.1 - 1.5e-06 27.9 6.7 6 7.3 0.0 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN85575.1 - 1e-05 25.3 4.0 1.9 8.5 0.0 6.5 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN85575.1 - 0.00012 21.5 0.3 15 5.6 0.0 6.1 5 2 1 6 6 4 0 Tetratricopeptide repeat Suf PF05843.9 KZN85575.1 - 0.0013 18.4 3.3 0.37 10.4 0.0 4.0 5 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_7 PF13176.1 KZN85575.1 - 0.0056 16.3 5.6 41 4.3 0.0 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN85575.1 - 0.012 15.9 13.1 5.8 7.6 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 KZN85575.1 - 0.013 15.4 19.7 0.21 11.5 2.6 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN85575.1 - 0.21 12.1 16.8 36 5.1 0.0 9.1 11 0 0 11 11 9 0 Tetratricopeptide repeat RrnaAD PF00398.15 KZN85576.1 - 4.8e-59 199.5 0.0 1.1e-58 198.2 0.0 1.6 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KZN85576.1 - 3.6e-11 43.1 0.0 7.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85576.1 - 8.8e-07 28.6 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN85576.1 - 5.7e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KZN85576.1 - 2e-05 24.2 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 KZN85576.1 - 3.6e-05 24.1 0.0 7.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN85576.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN85576.1 - 0.00022 20.6 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KZN85576.1 - 0.00056 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KZN85576.1 - 0.00098 18.3 0.0 0.002 17.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KZN85576.1 - 0.0019 18.5 0.0 0.0088 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KZN85576.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 KZN85576.1 - 0.0072 15.9 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KZN85576.1 - 0.038 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 KZN85576.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RRM_1 PF00076.17 KZN85578.1 - 1.8e-36 123.6 0.2 2.4e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN85578.1 - 1.9e-28 98.2 0.1 2.2e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85578.1 - 5.6e-13 48.5 0.4 1.9e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN85578.1 - 0.062 13.1 6.0 1.6 8.6 0.0 3.3 3 1 1 4 4 4 0 RNA binding motif TRP PF06011.7 KZN85579.1 - 7.1e-132 440.0 7.5 8.9e-132 439.7 5.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KZN85579.1 - 3.4e-38 130.8 0.4 5.6e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 ML-like domain EpsG PF14897.1 KZN85579.1 - 0.00082 18.4 1.2 0.00082 18.4 0.8 1.9 3 0 0 3 3 3 1 EpsG family Shisa PF13908.1 KZN85579.1 - 0.056 13.6 6.5 1.9 8.6 0.1 2.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2663 PF10864.3 KZN85579.1 - 0.1 12.7 4.9 1.1 9.5 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Protocadherin PF08374.6 KZN85579.1 - 0.72 9.4 0.0 0.72 9.4 0.0 2.6 2 1 0 2 2 2 0 Protocadherin HTH_32 PF13565.1 KZN85580.1 - 6.8e-07 29.9 1.9 0.0018 19.0 0.0 2.3 1 1 1 2 2 2 2 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KZN85580.1 - 0.0078 16.2 0.3 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Transposase WD40 PF00400.27 KZN85581.1 - 1.4e-56 186.4 18.6 8.2e-12 44.5 0.3 8.2 8 2 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KZN85581.1 - 2e-07 30.9 0.0 0.0028 17.3 0.0 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KZN85581.1 - 0.0015 16.7 5.1 0.35 8.9 0.0 4.6 1 1 2 5 5 5 1 Nucleoporin Nup120/160 IKI3 PF04762.7 KZN85581.1 - 0.026 12.3 0.0 0.035 11.9 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Cytochrom_D1 PF02239.11 KZN85581.1 - 0.032 12.5 0.0 0.24 9.6 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KZN85581.1 - 0.081 11.6 0.1 1.1 7.9 0.0 2.5 2 1 0 3 3 3 0 Nup133 N terminal like CAP_N PF01213.14 KZN85581.1 - 0.48 9.6 2.8 0.83 8.8 2.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Exo_endo_phos PF03372.18 KZN85582.1 - 5e-17 62.6 0.0 7.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 KZN85582.1 - 0.07 12.2 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Thi4 PF01946.12 KZN85583.1 - 1.2e-101 338.6 0.0 1.4e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KZN85583.1 - 4.2e-09 35.7 0.2 1.9e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN85583.1 - 1.7e-05 23.9 0.3 3.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN85583.1 - 5.1e-05 23.2 0.7 0.00013 21.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN85583.1 - 0.00011 21.9 0.2 0.00044 20.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KZN85583.1 - 0.00048 19.0 1.5 0.0053 15.6 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN85583.1 - 0.00068 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN85583.1 - 0.0015 18.4 0.7 0.0025 17.7 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN85583.1 - 0.0042 16.1 0.1 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KZN85583.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN85583.1 - 0.1 11.0 0.1 0.35 9.2 0.4 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 KZN85583.1 - 0.12 10.9 0.2 0.17 10.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 KZN85584.1 - 5e-31 107.7 28.6 5e-31 107.7 19.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN85584.1 - 0.061 13.1 2.6 0.09 12.5 0.3 2.4 2 0 0 2 2 2 0 MFS_1 like family Inhibitor_I10 PF12559.3 KZN85584.1 - 0.18 12.0 0.4 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Serine endopeptidase inhibitors SWI-SNF_Ssr4 PF08549.5 KZN85585.1 - 2.3e-269 895.3 23.8 2.6e-248 825.7 5.7 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Pil1 PF13805.1 KZN85586.1 - 3.1e-97 324.9 3.5 3.9e-97 324.6 2.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 KZN85586.1 - 0.086 13.0 0.5 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Spectrin PF00435.16 KZN85586.1 - 0.099 12.9 2.6 0.48 10.7 0.7 2.5 2 1 0 2 2 2 0 Spectrin repeat UPF0231 PF06062.6 KZN85586.1 - 0.1 12.4 0.1 2.5 8.0 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0231) Macoilin PF09726.4 KZN85586.1 - 0.8 7.9 4.9 0.89 7.7 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 KZN85586.1 - 2.5 7.6 7.8 0.64 9.5 0.2 2.9 2 1 0 2 2 2 0 Septum formation initiator Proteasome PF00227.21 KZN85587.1 - 3.7e-43 147.0 0.5 2.7e-41 140.9 0.4 2.1 1 1 0 1 1 1 1 Proteasome subunit Fungal_trans PF04082.13 KZN85588.1 - 4e-08 32.4 3.6 2e-07 30.1 2.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85588.1 - 3.5e-07 30.0 9.3 5.9e-07 29.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 KZN85589.1 - 3.3e-101 338.8 3.9 1.6e-99 333.2 0.5 2.0 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Staygreen PF12638.2 KZN85589.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Staygreen protein Cyc-maltodext_C PF10438.4 KZN85589.1 - 0.064 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Sugar_tr PF00083.19 KZN85590.1 - 4e-86 289.3 27.4 4.7e-86 289.1 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85590.1 - 3.1e-22 78.7 23.7 3.1e-22 78.7 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb2_6 PF00562.23 KZN85591.1 - 1.9e-117 392.2 0.3 2.6e-117 391.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KZN85591.1 - 1.2e-31 109.2 0.0 1.8e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 KZN85591.1 - 1.7e-25 88.7 0.1 4.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KZN85591.1 - 1.3e-24 86.7 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KZN85591.1 - 9.7e-24 82.9 0.0 2.5e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KZN85591.1 - 1.6e-14 53.9 0.0 5.3e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KZN85591.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Gly-zipper_OmpA PF13436.1 KZN85591.1 - 0.065 12.8 4.8 0.15 11.6 3.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Arf PF00025.16 KZN85592.1 - 1.4e-43 148.1 0.0 1.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KZN85592.1 - 4.8e-19 68.3 0.0 5.4e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN85592.1 - 9.3e-10 39.0 0.0 1.4e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KZN85592.1 - 5.3e-07 29.0 0.0 6.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN85592.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KZN85592.1 - 1.4e-05 24.4 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KZN85592.1 - 2.3e-05 23.8 0.0 0.00025 20.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 KZN85592.1 - 7.2e-05 21.6 0.4 0.00026 19.8 0.0 2.0 2 1 1 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 KZN85592.1 - 0.0011 18.8 0.0 0.016 15.0 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KZN85592.1 - 0.024 13.9 0.2 0.11 11.7 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B Actin PF00022.14 KZN85593.1 - 5.7e-143 476.0 0.0 6.5e-143 475.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KZN85593.1 - 0.03 12.9 0.0 1.1 7.7 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein Hep_59 PF07052.6 KZN85594.1 - 5.5e-19 68.4 0.1 5.5e-19 68.4 0.0 3.3 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Cut8_N PF14482.1 KZN85594.1 - 5.6 7.0 8.1 2.4 8.2 1.2 2.9 2 2 1 3 3 3 0 Cut8 proteasome-binding domain Sugar_tr PF00083.19 KZN85595.1 - 1.3e-94 317.3 23.5 1.6e-94 317.0 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85595.1 - 1.5e-29 102.8 42.0 4.8e-25 88.0 15.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.14 KZN85597.1 - 2e-30 105.9 0.0 7.8e-19 67.9 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN85597.1 - 1.7e-29 102.9 0.0 2.9e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN85597.1 - 0.00057 19.8 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN85597.1 - 0.002 17.1 0.1 0.023 13.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN85597.1 - 0.0022 16.9 1.0 0.0097 14.7 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN85597.1 - 0.0099 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.18 KZN85597.1 - 0.073 12.8 2.6 5.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif Pyr_redox_3 PF13738.1 KZN85597.1 - 0.094 12.7 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN85597.1 - 0.099 11.5 0.6 0.17 10.8 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein CFEM PF05730.6 KZN85598.1 - 2e-14 53.1 13.2 3.4e-14 52.4 9.2 1.4 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.12 KZN85599.1 - 3.8e-12 45.5 0.1 1.7e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase, family 2 Beta-lactamase PF00144.19 KZN85600.1 - 2.7e-30 105.5 0.0 4.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Acyl-CoA_dh_M PF02770.14 KZN85602.1 - 5e-07 29.1 0.0 1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DIOX_N PF14226.1 KZN85603.1 - 5.3e-17 62.4 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN85603.1 - 4.5e-13 49.3 0.0 7.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_11 PF13414.1 KZN85604.1 - 1.2e-10 40.9 11.9 7.5e-08 31.9 0.3 4.3 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 KZN85604.1 - 1.7e-10 40.6 7.4 0.0016 18.3 0.4 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN85604.1 - 6.6e-07 28.6 5.4 0.035 13.8 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN85604.1 - 1.8e-06 27.2 0.3 1.8e-06 27.2 0.2 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN85604.1 - 3.1e-05 23.5 0.2 3.1e-05 23.5 0.2 6.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN85604.1 - 0.00023 20.7 3.3 0.13 12.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN85604.1 - 0.0012 19.5 18.8 0.94 10.2 2.7 6.4 6 1 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN85604.1 - 0.0061 17.0 11.1 5.7 7.8 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN85604.1 - 0.11 12.9 0.4 0.11 12.9 0.3 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 KZN85604.1 - 0.18 11.7 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 PPR_3 PF13812.1 KZN85604.1 - 1.8 9.0 4.3 3.7 8.0 0.1 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_17 PF13431.1 KZN85604.1 - 8 6.9 8.0 2.1e+02 2.5 0.0 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat Rhodanese PF00581.15 KZN85606.1 - 4e-26 91.5 0.0 5.8e-07 29.8 0.0 4.5 4 0 0 4 4 4 4 Rhodanese-like domain DUF2263 PF10021.4 KZN85607.1 - 1.5e-26 93.1 0.0 2.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SKG6 PF08693.5 KZN85608.1 - 0.0016 17.6 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 KZN85608.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Glyco_hydro_15 PF00723.16 KZN85609.1 - 2.2e-18 66.0 0.0 2.7e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF605 PF04652.11 KZN85609.1 - 5.7 6.2 18.6 7.8 5.7 12.9 1.1 1 0 0 1 1 1 0 Vta1 like His_Phos_2 PF00328.17 KZN85610.1 - 3.3e-32 112.1 0.0 4.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 KZN85611.1 - 5.6e-09 36.1 0.0 7.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN85611.1 - 0.00056 19.6 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF3505 PF12013.3 KZN85612.1 - 2.6e-21 75.9 0.5 4e-21 75.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 KZN85612.1 - 1.7e-11 43.3 0.3 3.8e-11 42.2 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Frigida PF07899.6 KZN85612.1 - 0.21 10.3 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Frigida-like protein FAD_binding_4 PF01565.18 KZN85613.1 - 1.8e-23 82.5 0.8 3e-23 81.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN85613.1 - 1.2e-05 25.0 0.2 4.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 KZN85615.1 - 5.9e-29 100.8 22.9 5.9e-29 100.8 15.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN85615.1 - 0.002 16.4 0.7 0.004 15.4 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Polyketide_cyc2 PF10604.4 KZN85616.1 - 6.5e-10 39.3 0.0 8.2e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Zn_clus PF00172.13 KZN85617.1 - 1.8e-07 30.9 10.4 2.8e-07 30.3 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN85617.1 - 3e-05 22.8 0.1 0.076 11.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain p450 PF00067.17 KZN85618.1 - 3.9e-49 167.4 0.0 5.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Response_reg PF00072.19 KZN85619.1 - 1.6e-22 79.6 1.7 3e-22 78.7 0.2 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KZN85619.1 - 7.8e-22 77.0 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KZN85619.1 - 5.9e-11 42.2 1.4 8.1e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 KZN85619.1 - 5.6e-05 23.1 0.1 0.00019 21.4 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_7 PF12860.2 KZN85619.1 - 0.00065 19.6 0.1 0.51 10.3 0.0 3.3 2 1 1 3 3 3 1 PAS fold PAS_3 PF08447.6 KZN85619.1 - 0.0022 18.0 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.1 KZN85619.1 - 0.25 11.0 1.6 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 GHKL domain MFS_1 PF07690.11 KZN85620.1 - 1.4e-46 158.8 53.0 5.4e-46 156.9 35.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KZN85621.1 - 1.2e-21 77.1 0.7 7.3e-13 48.3 0.4 3.0 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KZN85621.1 - 2.9e-05 23.0 0.0 5.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KZN85621.1 - 6.4e-05 22.8 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN85621.1 - 0.00012 21.1 0.0 0.00068 18.6 0.0 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KZN85621.1 - 0.00042 19.3 0.0 0.0033 16.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN85621.1 - 0.0014 17.1 0.1 0.0046 15.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KZN85621.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN85621.1 - 0.0029 17.4 0.1 0.0054 16.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN85621.1 - 0.0045 16.1 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KZN85621.1 - 0.007 16.7 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.20 KZN85621.1 - 0.018 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme IlvN PF07991.7 KZN85621.1 - 0.079 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KZN85621.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CPSase_L_chain PF00289.17 KZN85621.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 KZN85621.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_25 PF01755.12 KZN85622.1 - 0.00036 20.2 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Sugar_tr PF00083.19 KZN85623.1 - 1.4e-83 280.9 25.0 1.7e-83 280.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85623.1 - 6.8e-23 80.9 33.6 6.8e-23 80.9 23.3 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN85623.1 - 1.3e-05 23.6 1.6 1.3e-05 23.6 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KZN85623.1 - 0.0011 17.3 3.0 0.0011 17.3 2.1 4.1 2 2 2 4 4 4 2 MFS/sugar transport protein DUF2530 PF10745.4 KZN85623.1 - 0.086 12.8 5.9 0.043 13.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) p450 PF00067.17 KZN85625.1 - 2.4e-72 243.9 0.0 2.9e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 KZN85627.1 - 3.6e-06 27.5 1.0 0.00024 21.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 KZN85627.1 - 9.3e-06 25.6 3.9 1.8e-05 24.6 1.3 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.13 KZN85628.1 - 1e-58 198.3 0.0 1.5e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.17 KZN85629.1 - 1.3e-53 182.1 0.0 1.6e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rcd1 PF04078.8 KZN85629.1 - 0.12 11.2 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like FAD_binding_3 PF01494.14 KZN85630.1 - 1.3e-96 323.8 0.0 1.5e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN85630.1 - 1.4e-06 28.3 0.0 5.2e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN85630.1 - 4.9e-06 25.6 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KZN85630.1 - 0.008 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KZN85630.1 - 0.013 15.4 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN85630.1 - 0.024 13.4 0.5 0.19 10.5 0.4 2.0 1 1 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KZN85630.1 - 0.028 14.7 0.0 2.4 8.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN85630.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Metal_resist PF13801.1 KZN85630.1 - 0.035 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance FAD_oxidored PF12831.2 KZN85630.1 - 0.056 12.5 0.2 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN85630.1 - 0.061 13.3 0.1 0.52 10.3 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN85630.1 - 0.16 10.4 0.1 0.3 9.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 KZN85631.1 - 1.5e-05 25.1 0.0 3.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN85631.1 - 0.00028 20.4 0.0 0.00081 18.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN85631.1 - 0.012 14.5 0.0 0.32 9.8 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein DUF1456 PF07308.8 KZN85631.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) KR PF08659.5 KZN85631.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 KZN85631.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 KZN85632.1 - 8.5e-17 60.8 0.0 1.6e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN85632.1 - 5.5e-09 35.8 7.1 0.00023 21.3 0.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KZN85632.1 - 1.8e-07 30.9 7.4 4.3e-07 29.7 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KZN85632.1 - 5e-06 26.4 12.4 0.0023 18.1 1.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN85632.1 - 1.5e-05 25.0 7.2 0.00036 20.6 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.7 KZN85632.1 - 8.2e-05 22.6 1.6 0.00019 21.4 1.1 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KZN85632.1 - 0.00046 20.2 0.8 0.4 10.8 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN85632.1 - 0.00051 20.1 1.1 0.065 13.4 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN85632.1 - 0.039 13.8 3.5 1.7 8.6 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Arena_RNA_pol PF06317.6 KZN85632.1 - 0.22 8.0 0.0 0.31 7.5 0.0 1.1 1 0 0 1 1 1 0 Arenavirus RNA polymerase ADH_zinc_N PF00107.21 KZN85633.1 - 1.4e-25 89.3 0.1 2.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN85633.1 - 2.2e-16 60.8 0.0 1.1e-15 58.6 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN85633.1 - 1.4e-05 24.8 0.3 0.0036 17.0 0.0 3.0 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 KZN85633.1 - 0.043 13.7 0.1 3 7.7 0.0 2.2 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Cupin_2 PF07883.6 KZN85634.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain 4HBT_3 PF13622.1 KZN85635.1 - 1.2e-40 139.9 0.8 1.5e-40 139.5 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KZN85635.1 - 6.2e-21 74.3 0.0 1.1e-15 57.4 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Aa_trans PF01490.13 KZN85636.1 - 2.8e-47 161.1 33.6 3.1e-47 160.9 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_cc PF11790.3 KZN85638.1 - 8.4e-67 225.0 0.9 9.7e-67 224.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Frataxin_Cyay PF01491.11 KZN85639.1 - 3.2e-33 113.7 0.0 4.2e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain FixH PF05751.6 KZN85639.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 FixH zf-CSL PF05207.8 KZN85640.1 - 4.8e-25 86.8 0.8 6e-25 86.5 0.6 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KZN85640.1 - 0.0082 16.0 0.3 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KZN85640.1 - 0.71 9.2 3.1 0.36 10.1 0.5 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding HAUS4 PF14735.1 KZN85641.1 - 3.5e-05 23.2 2.7 3.5e-05 23.2 1.9 2.0 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 4 DinB_2 PF12867.2 KZN85641.1 - 0.31 11.3 3.7 4.5 7.6 0.2 2.5 1 1 0 2 2 2 0 DinB superfamily Bromodomain PF00439.20 KZN85642.1 - 1.5e-38 130.5 0.5 2.3e-21 75.4 0.0 2.7 2 0 0 2 2 2 2 Bromodomain DUF3573 PF12097.3 KZN85642.1 - 1.1 7.7 5.1 1.9 7.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Utp12 PF04003.7 KZN85643.1 - 1.6e-22 79.4 0.0 2.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KZN85645.1 - 2.9e-14 52.2 3.7 4e-06 26.4 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat PPTA PF01239.17 KZN85646.1 - 7.6e-30 100.9 8.5 1.5e-08 33.5 0.0 4.6 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat RabGAP-TBC PF00566.13 KZN85647.1 - 5.2e-50 169.8 0.0 5.2e-50 169.8 0.0 2.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain V_ATPase_I PF01496.14 KZN85647.1 - 3.3 5.4 8.8 6.5 4.4 6.1 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dabb PF07876.7 KZN85648.1 - 4.6e-13 49.4 0.0 4.9e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Nepo_coat_N PF03689.10 KZN85648.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Glyoxalase PF00903.20 KZN85649.1 - 1.4e-16 60.6 0.1 1.9e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KZN85649.1 - 7e-13 48.5 0.1 1.5e-05 24.9 0.0 2.8 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KZN85649.1 - 1.7e-07 31.7 0.1 0.009 16.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 KZN85649.1 - 1.1e-06 28.6 0.0 0.18 11.6 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KZN85649.1 - 6.1e-06 26.2 0.0 0.0056 16.6 0.0 3.0 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ctf8 PF09696.5 KZN85650.1 - 1.1e-38 131.6 0.0 1.4e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Ctf8 NHR2 PF08788.6 KZN85650.1 - 0.0035 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 NHR2 domain like Cnl2_NKP2 PF09447.5 KZN85651.1 - 2.8e-27 94.1 0.7 2.8e-27 94.1 0.5 1.8 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF948 PF06103.6 KZN85651.1 - 0.004 16.9 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Rabaptin PF03528.10 KZN85651.1 - 0.023 14.6 1.9 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Rabaptin GlutR_dimer PF00745.15 KZN85651.1 - 0.043 13.7 0.9 0.043 13.7 0.6 1.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Elongin_A PF06881.6 KZN85651.1 - 0.095 13.0 0.2 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ATP-synt_B PF00430.13 KZN85651.1 - 0.25 11.1 3.1 2.8 7.7 0.8 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Toxin_39 PF15500.1 KZN85651.1 - 0.46 10.6 2.0 1.2 9.3 0.7 2.3 1 1 1 2 2 2 0 Putative RNase-like toxin MRG PF05712.8 KZN85652.1 - 4.6e-53 179.0 0.0 6.7e-53 178.4 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KZN85652.1 - 3.3e-08 33.1 3.0 6.5e-08 32.1 2.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KZN85652.1 - 0.015 14.9 1.9 0.041 13.5 1.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1741 PF08427.5 KZN85653.1 - 1.3e-92 309.5 0.1 3.6e-92 308.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MBOAT_2 PF13813.1 KZN85653.1 - 0.026 14.6 0.1 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Fe-S_biosyn PF01521.15 KZN85654.1 - 1.8e-18 66.5 0.0 2.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3275 PF11679.3 KZN85654.1 - 0.15 11.6 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF566 PF04484.7 KZN85654.1 - 5.8 6.3 7.8 7.5 5.9 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2407_C PF13373.1 KZN85655.1 - 8.8e-43 145.5 0.2 1.3e-42 145.0 0.2 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KZN85655.1 - 1.4e-31 108.5 0.0 2.8e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KZN85655.1 - 0.00046 19.5 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KZN85655.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like V-SNARE PF05008.10 KZN85656.1 - 2.6e-21 75.5 5.2 2.6e-21 75.5 3.6 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KZN85656.1 - 1.6e-15 56.9 4.5 1.6e-15 56.9 3.1 2.9 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KZN85656.1 - 0.00044 19.8 0.5 0.00044 19.8 0.3 2.5 2 1 1 3 3 3 1 Sec20 DUF1978 PF09321.5 KZN85656.1 - 0.00054 19.4 9.9 0.00071 19.0 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) Fusion_gly PF00523.13 KZN85656.1 - 0.00065 17.8 3.2 0.0036 15.4 0.2 2.2 2 0 0 2 2 2 1 Fusion glycoprotein F0 TMP_2 PF06791.8 KZN85656.1 - 0.015 14.9 3.5 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein Spc7 PF08317.6 KZN85656.1 - 0.063 11.9 12.5 0.029 13.0 5.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein End3 PF12761.2 KZN85656.1 - 0.76 9.3 10.2 0.025 14.2 2.5 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ZapA PF05164.8 KZN85656.1 - 0.84 9.6 12.9 0.48 10.4 0.1 3.6 2 1 0 2 2 2 0 Cell division protein ZapA Synaptobrevin PF00957.16 KZN85656.1 - 2 8.0 9.8 0.24 11.0 1.9 2.9 3 1 1 4 4 4 0 Synaptobrevin DUF912 PF06024.7 KZN85656.1 - 2.2 8.3 4.5 0.51 10.4 0.2 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sec8_exocyst PF04048.9 KZN85656.1 - 2.2 7.8 8.3 4.6 6.8 0.0 2.9 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain YqjK PF13997.1 KZN85656.1 - 3.1 8.0 7.0 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 YqjK-like protein DUF106 PF01956.11 KZN85656.1 - 4 6.9 7.6 0.67 9.4 0.5 2.4 1 1 1 2 2 2 0 Integral membrane protein DUF106 zf-C4H2 PF10146.4 KZN85656.1 - 6.3 6.7 8.2 1.2 9.1 1.0 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Histone_HNS PF00816.16 KZN85656.1 - 7.5 7.1 6.3 0.84 10.1 0.5 2.2 2 1 0 2 2 2 0 H-NS histone family TIP49 PF06068.8 KZN85657.1 - 6.1e-187 621.2 0.1 7.1e-187 620.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KZN85657.1 - 2e-11 43.3 0.7 7.8e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KZN85657.1 - 4e-11 43.2 0.1 3.9e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN85657.1 - 5e-06 26.6 0.0 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KZN85657.1 - 9.2e-06 25.8 0.2 0.15 12.1 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KZN85657.1 - 9.5e-05 22.0 0.1 0.00024 20.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KZN85657.1 - 0.00033 20.6 0.1 0.00067 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KZN85657.1 - 0.00069 19.3 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KZN85657.1 - 0.0013 18.2 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KZN85657.1 - 0.0013 17.8 0.2 0.0029 16.7 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KZN85657.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KZN85657.1 - 0.014 14.5 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KZN85657.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 KZN85657.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KZN85657.1 - 0.038 13.1 0.4 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 KZN85657.1 - 0.039 14.2 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN85657.1 - 0.061 14.1 0.1 0.16 12.7 0.0 1.9 2 1 0 2 2 1 0 AAA domain DnaB_C PF03796.10 KZN85657.1 - 0.083 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain T2SE PF00437.15 KZN85657.1 - 0.13 11.1 0.7 0.7 8.7 0.1 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein Ribosomal_L28 PF00830.14 KZN85658.1 - 1.9e-18 66.0 0.8 2.9e-18 65.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L28 family UPF0147 PF03685.8 KZN85659.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) CN_hydrolase PF00795.17 KZN85660.1 - 2.9e-20 72.4 0.0 4.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_transf_34 PF05637.7 KZN85661.1 - 2.6e-59 200.6 0.0 3.2e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF1270 PF06900.6 KZN85661.1 - 0.1 12.7 1.1 0.21 11.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Steroid_dh PF02544.11 KZN85662.1 - 5.6e-33 113.8 1.7 7.5e-33 113.4 1.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KZN85662.1 - 3.3e-06 26.5 1.6 4.6e-06 26.0 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KZN85662.1 - 4.8e-05 23.4 0.6 0.00011 22.2 0.4 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase An_peroxidase PF03098.10 KZN85663.1 - 4.8e-97 325.5 0.0 1e-77 261.7 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KZN85663.1 - 3.1e-08 32.5 0.0 2.1e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 DUF2359 PF10151.4 KZN85663.1 - 0.031 12.8 0.1 0.045 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF913 PF06025.7 KZN85664.1 - 1e-150 501.7 0.1 2.3e-149 497.3 0.0 2.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KZN85664.1 - 5.9e-96 321.3 0.0 1e-95 320.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KZN85664.1 - 8.9e-91 304.6 1.7 3.5e-90 302.6 1.2 2.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KZN85664.1 - 1e-31 109.0 7.8 1e-31 109.0 5.4 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Pribosyltran_N PF13793.1 KZN85665.1 - 2.1e-45 153.1 1.0 2.3e-44 149.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KZN85665.1 - 7.9e-39 133.2 1.8 3.8e-32 111.5 0.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KZN85665.1 - 4.6e-13 48.9 0.9 4e-12 45.9 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KZN85665.1 - 4.2e-05 22.8 0.2 7.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 KZN85665.1 - 0.012 15.3 1.3 0.022 14.4 0.9 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Ribosomal_S6e PF01092.14 KZN85666.1 - 7e-55 184.0 0.6 1.2e-53 180.1 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein S6e ATPgrasp_TupA PF14305.1 KZN85666.1 - 0.065 12.5 0.1 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 TupA-like ATPgrasp DUF3891 PF13030.1 KZN85667.1 - 0.024 14.1 0.1 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) HMG_box PF00505.14 KZN85668.1 - 6.9e-24 83.9 0.7 1.2e-23 83.0 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KZN85668.1 - 2.1e-09 37.6 0.2 4e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.18 KZN85669.1 - 4.6e-37 127.4 0.0 4.2e-32 111.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN85669.1 - 0.00094 18.9 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_17 PF13207.1 KZN85670.1 - 6.1e-07 30.2 0.0 1.9e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KZN85670.1 - 1.9e-05 24.3 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KZN85670.1 - 0.00023 21.4 0.0 0.00088 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KZN85670.1 - 0.00051 20.4 0.0 0.00082 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KZN85670.1 - 0.0089 16.3 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 KZN85670.1 - 0.024 14.6 0.1 0.085 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 KZN85670.1 - 0.039 13.9 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 KZN85670.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 KZN85670.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 KZN85670.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN85670.1 - 0.14 12.1 0.2 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Velvet PF11754.3 KZN85672.1 - 1.2e-56 191.5 1.0 6.3e-56 189.2 0.7 2.0 1 1 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 KZN85673.1 - 1.2e-78 262.6 0.0 2.2e-78 261.8 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family OrfB_Zn_ribbon PF07282.6 KZN85673.1 - 0.98 9.1 5.5 18 5.0 2.6 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain PHD PF00628.24 KZN85673.1 - 4.2 7.1 8.8 1.3 8.7 3.3 2.1 2 0 0 2 2 2 0 PHD-finger Acetyltransf_2 PF00797.12 KZN85675.1 - 1.4e-34 119.7 0.0 1.9e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Methyltransf_6 PF03737.10 KZN85676.1 - 2.7e-22 79.2 0.3 4.3e-22 78.6 0.2 1.4 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Thiolase_N PF00108.18 KZN85677.1 - 1.4e-76 257.0 3.1 1.4e-76 257.0 2.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN85677.1 - 3e-44 149.3 0.2 7.4e-44 148.1 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KZN85677.1 - 0.011 15.1 3.6 0.035 13.6 0.5 2.7 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KZN85677.1 - 0.029 14.3 0.0 0.092 12.7 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KZN85677.1 - 0.037 13.6 0.5 13 5.5 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF218 PF02698.12 KZN85678.1 - 1.4e-12 47.3 0.0 2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Glyco_trans_2_3 PF13632.1 KZN85678.1 - 0.039 13.6 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Drf_GBD PF06371.8 KZN85680.1 - 2.4e-16 59.6 1.0 2.4e-16 59.6 0.7 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Xpo1 PF08389.7 KZN85680.1 - 0.072 13.0 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Nramp PF01566.13 KZN85681.1 - 1.4e-94 316.8 19.3 1.4e-94 316.8 13.4 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.16 KZN85682.1 - 2.3e-42 144.2 15.4 2.8e-42 143.9 10.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 KZN85682.1 - 8.4e-05 22.0 6.8 8.4e-05 22.0 4.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 KZN85682.1 - 0.00076 19.6 7.6 0.043 14.0 0.8 2.7 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KZN85682.1 - 0.0069 13.7 6.1 0.0088 13.4 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KZN85682.1 - 0.012 14.7 4.0 0.043 12.9 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 KZN85682.1 - 0.06 12.2 7.6 0.078 11.9 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC37_N PF03234.9 KZN85682.1 - 0.076 13.3 7.4 0.1 12.8 5.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Glutaredoxin PF00462.19 KZN85682.1 - 0.16 11.9 1.3 0.3 11.0 0.2 2.0 2 0 0 2 2 2 0 Glutaredoxin Prefoldin_2 PF01920.15 KZN85682.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.8 2 1 2 4 4 4 0 Prefoldin subunit Mod_r PF07200.8 KZN85682.1 - 0.28 11.0 10.3 0.075 12.9 3.9 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 KZN85682.1 - 0.32 10.5 5.0 1.1 8.8 0.3 2.2 1 1 0 2 2 2 0 IncA protein Sec34 PF04136.10 KZN85682.1 - 0.66 9.6 5.2 0.76 9.4 2.2 1.9 1 1 0 2 2 2 0 Sec34-like family BLOC1_2 PF10046.4 KZN85682.1 - 0.76 9.9 8.6 8.2 6.6 2.1 3.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mnd1 PF03962.10 KZN85682.1 - 1.1 8.8 11.7 3.2 7.3 8.1 1.8 1 1 0 1 1 1 0 Mnd1 family DUF1090 PF06476.7 KZN85682.1 - 2 8.0 6.8 4 7.1 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) FliD_N PF02465.13 KZN85682.1 - 3.5 8.0 10.4 25 5.3 4.0 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Uso1_p115_C PF04871.8 KZN85682.1 - 4.6 7.1 14.0 13 5.7 9.7 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.7 KZN85682.1 - 4.8 6.9 9.0 2 8.1 1.4 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4337 PF14235.1 KZN85682.1 - 6.5 6.5 9.1 0.54 10.0 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Glyco_hydro_26 PF02156.10 KZN85683.1 - 3.4e-76 256.6 2.1 4.2e-76 256.4 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 SAPS PF04499.10 KZN85684.1 - 1.7e-203 676.5 0.0 7.8e-202 671.0 0.0 2.5 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 KZN85686.1 - 5.2e-46 156.1 0.0 8.3e-46 155.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KZN85686.1 - 2.5e-18 64.9 0.7 4.8e-18 64.0 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KZN85686.1 - 5e-09 35.9 0.0 1.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 SLBB domain MFS_1 PF07690.11 KZN85687.1 - 1.7e-49 168.4 27.3 2.2e-48 164.7 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Colicin_C PF12106.3 KZN85687.1 - 3.4 7.3 5.7 1 8.9 0.9 2.2 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain MFS_1_like PF12832.2 KZN85687.1 - 5.3 6.9 10.9 3.4 7.5 1.2 3.1 3 0 0 3 3 3 0 MFS_1 like family Nup96 PF12110.3 KZN85688.1 - 5.1e-91 304.7 0.2 9.5e-91 303.9 0.1 1.5 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KZN85688.1 - 2.4e-47 160.3 0.0 3.7e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KZN85688.1 - 2.5e-14 53.4 104.1 1.2e-09 38.3 26.9 11.1 5 2 6 11 11 11 4 Nucleoporin FG repeat region adh_short PF00106.20 KZN85689.1 - 6.9e-13 48.8 1.3 8.4e-13 48.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN85689.1 - 3.7e-06 26.7 0.2 6.3e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KZN85689.1 - 0.00086 19.6 0.1 0.0022 18.3 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.1 KZN85689.1 - 0.0018 18.1 0.2 0.0032 17.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HEM4 PF02602.10 KZN85689.1 - 0.0038 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD 3HCDH_N PF02737.13 KZN85689.1 - 0.037 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AMP-binding PF00501.23 KZN85690.1 - 2.5e-91 306.1 0.1 3.2e-91 305.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN85690.1 - 8e-23 81.1 1.0 3.2e-21 76.0 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain APH PF01636.18 KZN85691.1 - 2.2e-12 47.2 0.0 2e-11 44.0 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_M20 PF01546.23 KZN85692.1 - 1.5e-28 99.6 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 KZN85692.1 - 1.1e-05 25.1 0.0 4.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 KZN85692.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PALP PF00291.20 KZN85693.1 - 9.1e-56 189.3 0.3 9.1e-56 189.3 0.2 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 KZN85693.1 - 6.7e-29 100.7 0.1 1.3e-28 99.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN85693.1 - 3.4e-18 65.4 0.0 9.8e-18 63.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KZN85693.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M28 Beta-Casp PF10996.3 KZN85693.1 - 0.088 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Beta-Casp domain GET2 PF08690.5 KZN85694.1 - 7.7e-08 31.9 1.1 1.4e-07 31.0 0.3 1.6 2 0 0 2 2 2 1 GET complex subunit GET2 XPC-binding PF09280.6 KZN85694.1 - 0.0067 15.8 1.6 1.3 8.5 0.1 2.6 2 0 0 2 2 2 2 XPC-binding domain Neisseria_TspB PF05616.8 KZN85694.1 - 8.5 4.6 6.2 12 4.1 4.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Homeobox_KN PF05920.6 KZN85695.1 - 9.7e-16 57.1 1.2 3e-15 55.6 0.8 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KZN85695.1 - 2.6e-07 30.1 3.3 5.4e-07 29.1 2.3 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KZN85695.1 - 0.017 15.4 38.9 0.029 14.6 2.4 5.6 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN85695.1 - 0.022 15.0 3.5 0.022 15.0 2.4 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type HA PF03457.9 KZN85695.1 - 0.057 13.5 0.5 0.32 11.1 0.1 2.5 3 0 0 3 3 3 0 Helicase associated domain zf-met PF12874.2 KZN85695.1 - 0.078 13.2 12.7 0.34 11.1 0.0 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 KZN85695.1 - 1.4 8.9 12.4 0.056 13.3 4.0 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KZN85696.1 - 3.4e-40 137.7 29.7 4.2e-40 137.4 20.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 KZN85696.1 - 1.3 8.7 9.8 3.5 7.3 0.1 3.6 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase NAD_binding_10 PF13460.1 KZN85697.1 - 2.3e-14 53.7 0.0 3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 KZN85698.1 - 4.1e-18 65.2 0.0 7.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85698.1 - 3.8e-09 36.2 12.4 6.5e-09 35.5 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Octopine_DH PF02317.12 KZN85699.1 - 1.6e-42 144.7 0.0 2.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 KZN85699.1 - 1.2e-11 44.6 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 KZN85699.1 - 0.00042 20.2 0.1 0.00084 19.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN85699.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KZN85699.1 - 0.002 18.5 0.0 0.0053 17.1 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KZN85699.1 - 0.0027 17.1 0.0 0.0078 15.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 KZN85699.1 - 0.0031 16.4 0.1 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KZN85699.1 - 0.0062 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN85699.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN85699.1 - 0.02 15.2 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN85699.1 - 0.023 13.1 0.1 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KZN85699.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KZN85699.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN85699.1 - 0.071 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN85699.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KZN85700.1 - 2.2e-56 191.0 11.4 2.2e-56 191.0 7.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85700.1 - 2.3e-13 49.5 11.7 2.3e-13 49.5 8.1 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter DUF791 PF05631.9 KZN85700.1 - 2.1e-06 26.6 6.1 5e-05 22.1 1.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KZN85700.1 - 7.6e-06 25.6 2.7 0.02 14.6 0.0 3.4 3 0 0 3 3 3 2 MFS_1 like family TRI12 PF06609.8 KZN85700.1 - 9.9e-05 20.7 4.2 0.00016 19.9 2.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NUDIX PF00293.23 KZN85701.1 - 4.3e-11 42.5 0.0 7.5e-11 41.8 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain gp32 PF08804.5 KZN85703.1 - 0.099 12.7 0.2 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like TrkH PF02386.11 KZN85704.1 - 2.6e-14 52.6 1.2 4.4e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1049 PF06305.6 KZN85704.1 - 0.24 10.9 5.8 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TrkH PF02386.11 KZN85705.1 - 3.3e-08 32.5 0.0 3.5e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Cation transport protein Alk_phosphatase PF00245.15 KZN85706.1 - 4.1e-69 233.2 0.1 6.3e-69 232.6 0.1 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 KZN85706.1 - 6.1e-08 32.1 4.2 1.6e-06 27.5 2.9 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN85706.1 - 1.9e-07 30.7 0.8 2.9e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN85706.1 - 0.00036 19.0 0.2 0.00059 18.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 KZN85706.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Metalloenzyme PF01676.13 KZN85706.1 - 0.054 12.8 0.6 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily FabA PF07977.8 KZN85707.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 FabA-like domain Zn_clus PF00172.13 KZN85708.1 - 8.5e-05 22.3 8.7 0.00014 21.7 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YihI PF04220.7 KZN85708.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) Fungal_trans PF04082.13 KZN85709.1 - 1.9e-20 72.8 0.9 4.8e-20 71.5 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85709.1 - 1e-07 31.7 12.5 1e-07 31.7 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4319 PF14203.1 KZN85709.1 - 0.0059 16.1 0.0 0.077 12.5 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4319) C2 PF00168.25 KZN85710.1 - 6.3e-21 74.0 0.0 1.4e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF3332 PF11810.3 KZN85710.1 - 0.18 11.4 1.8 0.38 10.4 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) IMS PF00817.15 KZN85712.1 - 5.8e-37 126.7 0.0 1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KZN85712.1 - 4.4e-12 46.0 0.1 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KZN85712.1 - 2.3e-05 24.1 0.0 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif HHH_8 PF14716.1 KZN85712.1 - 0.016 15.3 0.0 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_5 PF14520.1 KZN85712.1 - 0.046 13.8 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix domain Reprolysin_5 PF13688.1 KZN85713.1 - 3.8e-60 203.1 9.1 3.8e-60 203.1 6.3 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KZN85713.1 - 5.7e-45 153.3 4.1 1.2e-44 152.3 2.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KZN85713.1 - 6.9e-45 153.2 5.1 1.3e-44 152.3 3.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KZN85713.1 - 1.4e-19 70.0 34.1 1.4e-19 70.0 23.6 4.5 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 KZN85713.1 - 7.6e-17 61.9 3.3 9.8e-17 61.6 0.3 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KZN85713.1 - 3.3e-06 26.9 0.0 7.1e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Reprolysin family propeptide Mid2 PF04478.7 KZN85713.1 - 0.0029 17.0 0.1 0.0098 15.3 0.1 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Peptidase_M10 PF00413.19 KZN85713.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Matrixin EF-hand_1 PF00036.27 KZN85714.1 - 1.1e-13 49.3 2.1 5.3e-05 22.2 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KZN85714.1 - 2.1e-12 45.8 6.9 1.7e-05 24.2 0.2 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KZN85714.1 - 4.2e-12 46.0 4.0 6.8e-07 29.3 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KZN85714.1 - 6.9e-11 41.5 0.9 3.4e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 KZN85714.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 KZN85714.1 - 0.55 9.6 8.2 4.4 6.8 0.3 3.3 3 0 0 3 3 3 0 EF hand Zn_clus PF00172.13 KZN85715.1 - 1.2 9.0 8.3 2.4 8.1 5.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.3 KZN85716.1 - 1.1e-56 191.1 0.0 1.9e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KZN85716.1 - 1.8e-13 50.8 0.0 4.3e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KZN85716.1 - 1.7e-10 40.3 0.0 5.1e-10 38.8 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KZN85716.1 - 1.7e-05 24.0 0.0 0.13 11.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN85716.1 - 3.5e-05 23.5 0.0 0.00067 19.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KZN85716.1 - 5.4e-05 22.7 0.0 0.0025 17.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 KZN85716.1 - 0.00013 21.6 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN85716.1 - 0.00055 20.0 0.5 0.0022 18.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KZN85716.1 - 0.00068 19.2 0.0 0.0019 17.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KZN85716.1 - 0.0028 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KZN85716.1 - 0.003 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN85716.1 - 0.0048 16.9 0.1 0.11 12.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KZN85716.1 - 0.0049 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 KZN85716.1 - 0.0052 16.6 0.1 3.7 7.3 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit TIP49 PF06068.8 KZN85716.1 - 0.018 13.7 0.1 0.046 12.4 0.1 1.6 1 1 1 2 2 2 0 TIP49 C-terminus AAA_30 PF13604.1 KZN85716.1 - 0.021 14.4 0.1 0.053 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN85716.1 - 0.039 14.7 0.1 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF927 PF06048.6 KZN85716.1 - 0.045 13.0 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) PIF1 PF05970.9 KZN85716.1 - 0.046 12.6 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.1 KZN85716.1 - 0.1 12.1 0.1 5.6 6.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.1 KZN85716.1 - 0.11 12.1 0.0 0.6 9.7 0.0 2.1 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_18 PF13238.1 KZN85716.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KZN85716.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF605 PF04652.11 KZN85716.1 - 2.8 7.2 9.8 4.1 6.7 6.8 1.1 1 0 0 1 1 1 0 Vta1 like Aminotran_1_2 PF00155.16 KZN85717.1 - 2.1e-58 198.0 0.0 1.5e-37 129.4 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II zf-MYND PF01753.13 KZN85718.1 - 0.92 9.4 6.5 3 7.7 4.5 1.9 1 0 0 1 1 1 0 MYND finger SR-25 PF10500.4 KZN85718.1 - 3.9 6.8 46.8 0.011 15.2 6.8 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Baculo_PEP_C PF04513.7 KZN85719.1 - 0.032 14.0 4.4 0.59 9.9 0.5 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YbaJ PF10757.4 KZN85719.1 - 0.067 13.3 0.8 0.95 9.6 0.1 2.9 2 1 0 2 2 2 0 Biofilm formation regulator YbaJ Rifin_STEVOR PF02009.11 KZN85719.1 - 0.12 12.0 2.9 4.4 6.8 0.2 3.1 3 1 0 3 3 3 0 Rifin/stevor family PgaD PF13994.1 KZN85719.1 - 8 5.9 10.7 0.66 9.4 0.1 3.4 4 0 0 4 4 4 0 PgaD-like protein Ald_Xan_dh_C2 PF02738.13 KZN85720.1 - 1.7e-195 650.4 0.7 2.4e-195 650.0 0.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KZN85720.1 - 7.8e-50 168.6 0.0 1.6e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KZN85720.1 - 8.1e-33 112.8 0.0 2.1e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KZN85720.1 - 5.2e-31 106.6 2.2 1.1e-30 105.5 0.1 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KZN85720.1 - 1.2e-28 98.8 0.0 2.5e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KZN85720.1 - 4.6e-07 29.4 2.4 4.7e-07 29.4 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_4 PF07993.7 KZN85722.1 - 1.8e-71 240.0 0.0 2.9e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN85722.1 - 4.9e-71 239.3 0.0 8.7e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KZN85722.1 - 7.7e-14 51.6 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN85722.1 - 1.3e-09 38.1 0.0 3.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN85722.1 - 5.6e-09 36.8 0.0 2.8e-08 34.6 0.0 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KZN85722.1 - 2.9e-06 26.2 0.0 6.1e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN85722.1 - 0.0021 17.0 0.0 0.045 12.6 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN85722.1 - 0.0021 18.0 0.0 0.096 12.6 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN85722.1 - 0.0098 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KZN85722.1 - 0.028 14.3 0.7 0.14 12.1 0.1 2.5 2 1 0 2 2 2 0 short chain dehydrogenase Prok-E2_E PF14462.1 KZN85722.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family E Pro_CA PF00484.14 KZN85723.1 - 3.8e-43 147.1 0.0 5.2e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase AAA PF00004.24 KZN85724.1 - 2.2e-18 66.7 0.0 5.5e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN85724.1 - 0.0097 16.0 0.1 0.16 12.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 KZN85724.1 - 0.016 14.0 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.7 KZN85724.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN85724.1 - 0.022 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KZN85724.1 - 0.038 14.8 0.1 0.2 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KZN85724.1 - 0.11 12.4 1.0 0.53 10.2 0.4 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 KZN85724.1 - 0.14 12.0 0.2 0.65 9.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KZN85725.1 - 7.7e-59 196.0 2.8 1.7e-16 60.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN85725.1 - 2.7e-50 165.7 4.6 1.2e-12 46.9 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 KZN85725.1 - 1.9e-31 104.9 1.5 3e-08 33.1 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KZN85725.1 - 1.4e-30 105.0 0.8 1.1e-08 35.3 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN85725.1 - 2.1e-27 94.5 6.3 6e-10 39.0 0.0 6.0 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Baculo_PEP_C PF04513.7 KZN85726.1 - 0.051 13.3 0.2 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4279 PF14106.1 KZN85726.1 - 0.056 13.3 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Sulfatase PF00884.18 KZN85727.1 - 6.9e-15 55.0 0.1 1e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN85727.1 - 1.7e-06 27.5 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 KZN85727.1 - 0.0076 15.1 0.4 0.016 14.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.12 KZN85727.1 - 0.0099 14.3 0.1 0.018 13.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Arylsulfotran_2 PF14269.1 KZN85728.1 - 2.2e-43 148.5 1.3 3.2e-43 147.9 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN85728.1 - 5.7e-12 44.9 3.0 2e-10 39.7 2.2 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.13 KZN85729.1 - 1.1e-18 67.1 2.8 1.1e-18 67.1 1.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85729.1 - 0.00013 21.7 10.0 0.00022 21.0 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.15 KZN85732.1 - 4.3e-74 249.5 0.0 6.9e-74 248.8 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.3 KZN85733.1 - 1.3e-06 27.2 0.1 2e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85733.1 - 0.00072 19.4 4.6 0.0015 18.3 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1422 PF07226.6 KZN85733.1 - 0.014 15.0 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Pyr_redox_3 PF13738.1 KZN85735.1 - 1.2e-26 94.0 0.0 1.5e-25 90.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN85735.1 - 2e-13 49.3 0.1 3.8e-10 38.5 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN85735.1 - 2.9e-10 40.0 0.1 1e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN85735.1 - 4.5e-08 33.2 0.0 8.4e-06 25.7 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN85735.1 - 5.5e-07 28.8 0.2 0.0028 16.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN85735.1 - 1e-05 25.3 0.6 0.00094 18.9 0.0 3.7 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KZN85735.1 - 0.001 18.0 0.0 0.0075 15.2 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN85735.1 - 0.0011 19.3 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 KZN85735.1 - 0.044 13.8 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 KZN85735.1 - 0.046 12.6 0.2 0.19 10.6 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Aldo_ket_red PF00248.16 KZN85736.1 - 8e-69 231.5 0.0 9.1e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans2 PF04188.8 KZN85738.1 - 8.1e-63 212.8 12.5 8.7e-62 209.4 8.7 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3437 PF11919.3 KZN85739.1 - 4.1e-32 109.7 0.0 1.3e-31 108.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 KZN85739.1 - 0.00011 21.6 0.4 0.22 10.8 0.0 3.0 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KZN85739.1 - 0.0019 18.1 0.9 0.71 10.1 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Pkinase PF00069.20 KZN85740.1 - 4.3e-30 104.7 0.0 1.4e-29 103.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85740.1 - 3.6e-06 26.2 0.0 0.071 12.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KZN85740.1 - 0.0021 17.8 0.1 0.0069 16.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3405 PF11885.3 KZN85741.1 - 3.8e-171 569.6 1.6 6.2e-171 568.9 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1376 PF07120.6 KZN85741.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) DUF1162 PF06650.7 KZN85742.1 - 3e-88 295.6 0.0 3.2e-87 292.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KZN85742.1 - 1.2e-41 140.9 0.0 3.6e-41 139.4 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KZN85742.1 - 4.1e-06 26.8 0.1 3e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain Urease_beta PF00699.15 KZN85742.1 - 0.091 12.6 0.1 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Urease beta subunit BA14K PF07886.6 KZN85742.1 - 1.4 8.6 1.1 3 7.6 0.8 1.5 1 0 0 1 1 1 0 BA14K-like protein DUF3429 PF11911.3 KZN85743.1 - 4.4e-40 136.9 11.5 6.1e-40 136.4 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 KZN85744.1 - 9.7e-72 240.7 1.7 1.7e-71 239.9 1.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KZN85744.1 - 6.1e-63 212.3 0.0 8.1e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KZN85744.1 - 0.013 14.7 0.3 2 7.6 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 KZN85745.1 - 2.8e-66 223.0 0.3 4.9e-66 222.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KZN85745.1 - 7.7e-43 145.8 0.0 2.7e-42 144.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN85745.1 - 6.7e-06 26.9 0.1 3.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN85745.1 - 1.1e-05 25.2 0.0 3.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN85745.1 - 1.3e-05 25.2 0.7 6.3e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN85745.1 - 0.00011 22.3 1.6 0.0095 16.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KZN85745.1 - 0.00012 20.9 0.0 0.00012 20.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 KZN85745.1 - 0.00028 20.3 1.5 0.11 11.9 0.3 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 KZN85745.1 - 0.00059 18.9 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KZN85745.1 - 0.0016 18.1 0.3 0.0047 16.6 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KZN85745.1 - 0.0021 17.9 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN85745.1 - 0.0027 17.1 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KZN85745.1 - 0.011 14.8 2.6 0.028 13.5 0.2 2.4 2 1 1 3 3 3 0 Zeta toxin AAA_28 PF13521.1 KZN85745.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KZN85745.1 - 0.018 14.9 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KZN85745.1 - 0.02 14.0 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KZN85745.1 - 0.024 14.5 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN85745.1 - 0.047 14.0 0.3 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KZN85745.1 - 0.053 13.1 0.3 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KZN85745.1 - 0.058 12.5 0.5 1.2 8.1 0.0 2.6 3 0 0 3 3 3 0 KaiC NTP_transferase PF00483.18 KZN85747.1 - 4.4e-49 167.0 0.0 8.6e-49 166.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KZN85747.1 - 2.9e-17 61.3 23.9 4.5e-10 38.5 3.0 4.5 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KZN85747.1 - 1.9e-10 41.0 0.0 3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KZN85747.1 - 1.2e-06 27.9 3.4 1.2e-06 27.9 2.3 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KZN85747.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 KZN85748.1 - 3e-10 40.2 0.2 1.3e-05 25.1 0.1 2.8 1 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KZN85748.1 - 0.0043 16.7 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 KR domain NYD-SP28 PF14772.1 KZN85748.1 - 0.59 10.2 5.1 1 9.4 3.6 1.4 1 0 0 1 1 1 0 Sperm tail Suc_Fer-like PF06999.7 KZN85749.1 - 2.8e-35 122.4 0.0 1e-34 120.5 0.0 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like zf-H2C2_2 PF13465.1 KZN85750.1 - 2.3e-16 59.1 29.8 1e-06 28.7 0.5 4.7 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KZN85750.1 - 3.9e-16 58.3 39.7 0.00011 22.3 3.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN85750.1 - 1.9e-05 24.6 36.4 0.024 14.9 3.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger TFIIA PF03153.8 KZN85750.1 - 3.2 7.5 17.2 4 7.2 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.16 KZN85751.1 - 8e-34 117.1 0.0 1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.1 KZN85752.1 - 6.5e-40 135.9 0.0 1.3e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KZN85752.1 - 1.2e-33 115.0 0.0 2.3e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 KZN85752.1 - 1.4e-30 106.4 3.5 2.5e-30 105.6 2.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 KZN85752.1 - 5.1e-08 32.4 0.1 1.2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 KZN85752.1 - 0.07 13.3 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 PH domain WD40 PF00400.27 KZN85753.1 - 3.5e-40 134.4 12.5 1.8e-07 30.7 0.0 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 KZN85753.1 - 1.5e-10 40.5 1.3 3.7e-10 39.3 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN85753.1 - 1.1e-07 31.2 0.3 2.2e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KZN85753.1 - 6.2e-07 27.9 4.2 0.0022 16.2 0.0 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KZN85753.1 - 0.013 14.3 0.7 6.1 5.4 0.0 3.5 3 1 1 4 4 4 0 Nup133 N terminal like Hira PF07569.6 KZN85753.1 - 0.073 12.2 0.1 3.2 6.8 0.0 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split GST_N_2 PF13409.1 KZN85754.1 - 5.4e-09 35.9 0.0 1.7e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KZN85754.1 - 8.5e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN85754.1 - 3.4e-07 30.0 3.5 5.8e-07 29.3 2.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN85754.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pectate_lyase PF03211.8 KZN85755.1 - 4.8e-61 205.9 4.5 5.8e-61 205.6 3.1 1.0 1 0 0 1 1 1 1 Pectate lyase Uds1 PF15456.1 KZN85756.1 - 4.6e-48 162.3 0.8 4.6e-48 162.3 0.5 8.3 4 1 3 7 7 7 1 Up-regulated During Septation TPR_MLP1_2 PF07926.7 KZN85756.1 - 0.00019 21.1 81.6 0.19 11.4 8.7 9.1 3 1 4 8 8 8 7 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 KZN85756.1 - 0.0018 16.8 33.8 0.0018 16.8 23.4 5.5 4 1 3 7 7 7 3 Weak chloroplast movement under blue light Rab5-bind PF09311.6 KZN85756.1 - 0.0042 16.9 22.3 0.0042 16.9 15.5 6.1 2 1 5 7 7 7 4 Rabaptin-like protein HisKA PF00512.20 KZN85756.1 - 0.012 15.5 0.8 0.012 15.5 0.6 9.2 3 1 7 10 10 10 0 His Kinase A (phospho-acceptor) domain DUF1192 PF06698.6 KZN85756.1 - 0.14 11.9 0.1 0.14 11.9 0.1 7.7 8 1 0 8 8 8 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 KZN85756.1 - 0.89 9.4 100.9 0.81 9.5 6.3 9.7 4 1 5 9 9 9 0 Tropomyosin like MFS_1 PF07690.11 KZN85757.1 - 2.8e-25 88.8 30.1 2.8e-25 88.8 20.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN85757.1 - 0.026 14.2 0.5 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 MFS_1 like family DUF2929 PF11151.3 KZN85757.1 - 0.028 14.4 3.2 0.51 10.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) UCR_hinge PF02320.11 KZN85758.1 - 5.6e-26 90.2 8.0 1.2e-25 89.2 5.5 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF1510 PF07423.6 KZN85758.1 - 0.39 10.0 25.6 0.46 9.8 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 KZN85758.1 - 0.7 9.1 18.1 0.87 8.8 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC27 PF09507.5 KZN85758.1 - 2.6 7.1 28.1 3.2 6.8 19.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 KZN85758.1 - 3.5 6.1 12.0 3.8 6.0 8.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KZN85758.1 - 3.8 5.4 16.0 4.2 5.2 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KZN85758.1 - 4.2 4.9 12.7 4.7 4.7 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T PF15511.1 KZN85758.1 - 5.9 6.0 26.2 7 5.7 18.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Mitofilin PF09731.4 KZN85758.1 - 6 5.4 24.5 8 4.9 17.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2201_N PF13203.1 KZN85758.1 - 6.2 5.9 10.6 7.3 5.6 7.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain GAGA_bind PF06217.7 KZN85758.1 - 9.5 6.0 8.3 11 5.8 5.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family WWbp PF10349.4 KZN85759.1 - 3.5e-22 79.4 2.6 1.1e-21 77.8 0.8 1.9 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 KZN85759.1 - 0.00018 21.2 0.0 0.038 13.7 0.0 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Acyltransferase PF01553.16 KZN85760.1 - 6.4e-10 38.5 0.0 1.5e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Prenyltransf PF01255.14 KZN85761.1 - 7.6e-82 273.7 0.0 1.3e-81 272.9 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 KZN85762.1 - 5.5e-114 381.1 0.0 9.4e-114 380.3 0.0 1.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN85762.1 - 1.9e-08 34.5 0.1 3.2e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KZN85762.1 - 3.9e-08 33.4 0.6 7e-07 29.4 0.3 2.3 3 0 0 3 3 3 1 NADH(P)-binding NmrA PF05368.8 KZN85762.1 - 0.00025 20.3 0.5 0.0004 19.7 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KZN85762.1 - 0.00034 19.3 0.1 0.00054 18.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IlvN PF07991.7 KZN85762.1 - 0.00041 19.7 0.2 0.0094 15.3 0.1 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KZN85762.1 - 0.0017 18.7 0.2 0.004 17.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KZN85762.1 - 0.012 15.8 0.3 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 KZN85762.1 - 0.053 13.8 0.2 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aha1_N PF09229.6 KZN85763.1 - 3.2e-37 127.4 0.6 5.6e-37 126.6 0.4 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KZN85763.1 - 2.9e-17 62.9 0.5 7.1e-17 61.6 0.3 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Flu_PB1 PF00602.12 KZN85763.1 - 0.14 9.9 0.0 0.19 9.4 0.0 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 MFS_1 PF07690.11 KZN85765.1 - 4.3e-40 137.5 44.1 1.5e-32 112.7 15.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN85765.1 - 0.0016 18.2 5.3 0.0023 17.6 1.6 2.9 2 1 0 2 2 2 1 MFS_1 like family FBPase PF00316.15 KZN85766.1 - 8.7e-117 389.5 0.0 1e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase V_ATPase_I PF01496.14 KZN85767.1 - 1.2e-297 988.9 0.0 1.4e-297 988.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 KZN85767.1 - 0.028 14.2 0.1 0.075 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CheZ PF04344.8 KZN85767.1 - 0.14 11.8 1.0 0.62 9.6 0.1 2.3 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF3669 PF12417.3 KZN85768.1 - 0.09 12.5 0.1 1.6 8.5 0.0 2.9 2 1 1 3 3 3 0 Zinc finger protein PH_6 PF15406.1 KZN85770.1 - 9.9e-38 128.6 4.1 9.9e-38 128.6 2.8 4.2 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KZN85770.1 - 0.00096 19.3 0.0 0.0032 17.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_4 PF15404.1 KZN85770.1 - 0.28 10.7 0.0 0.28 10.7 0.0 4.4 3 1 1 4 4 4 0 Pleckstrin homology domain bZIP_1 PF00170.16 KZN85771.1 - 5.6e-06 26.2 7.2 1.1e-05 25.2 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN85771.1 - 0.00036 20.2 9.8 0.00078 19.2 6.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper SlyX PF04102.7 KZN85771.1 - 0.17 12.2 1.9 0.39 11.1 1.3 1.5 1 0 0 1 1 1 0 SlyX Bap31 PF05529.7 KZN85771.1 - 0.24 10.8 3.9 0.38 10.1 2.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Asn_synthase PF00733.16 KZN85772.1 - 5.5e-50 170.2 0.0 7.6e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KZN85772.1 - 8.9e-07 28.6 0.0 4.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KZN85772.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KZN85772.1 - 0.00015 21.0 0.1 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein VPS9 PF02204.13 KZN85773.1 - 2e-31 108.0 0.0 3.8e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KZN85773.1 - 1.2e-09 37.4 0.3 1.7e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 CUE domain Abhydrolase_6 PF12697.2 KZN85774.1 - 3e-26 92.6 0.2 7.1e-26 91.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN85774.1 - 2.8e-05 23.8 0.0 4.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN85774.1 - 0.00011 21.8 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KZN85774.1 - 0.011 15.3 0.1 0.053 13.0 0.0 2.1 3 0 0 3 3 3 0 PGAP1-like protein Ceramidase PF05875.7 KZN85775.1 - 3.5e-109 363.9 15.2 5.4e-109 363.3 10.6 1.3 1 1 0 1 1 1 1 Ceramidase MerC PF03203.9 KZN85775.1 - 0.69 10.2 8.8 17 5.8 3.8 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein Mito_carr PF00153.22 KZN85776.1 - 2.4e-56 187.4 2.5 5.9e-20 70.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FA_desaturase PF00487.19 KZN85777.1 - 6.4 6.1 8.3 11 5.4 5.7 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Prefoldin_2 PF01920.15 KZN85778.1 - 1.4e-17 63.4 7.1 1.7e-17 63.0 4.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 KZN85778.1 - 0.051 13.7 0.5 0.051 13.7 0.4 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.9 KZN85778.1 - 0.13 10.8 5.5 0.14 10.6 3.8 1.0 1 0 0 1 1 1 0 Tektin family DUF641 PF04859.7 KZN85778.1 - 0.42 10.3 4.7 3.2 7.5 0.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2681 PF10883.3 KZN85778.1 - 1.1 9.5 6.2 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Sigma54_AID PF00309.15 KZN85778.1 - 1.6 8.2 7.1 0.32 10.4 2.0 2.0 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) DUF4200 PF13863.1 KZN85778.1 - 5 7.0 9.1 11 6.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KZN85778.1 - 6.5 6.8 6.9 16 5.6 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HMG_box PF00505.14 KZN85779.1 - 1.3e-13 50.9 0.3 2.5e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KZN85779.1 - 0.00085 19.6 0.2 0.00085 19.6 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain PHD PF00628.24 KZN85780.1 - 3.4e-08 33.0 9.6 3.4e-08 33.0 6.7 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KZN85780.1 - 0.0064 15.7 5.8 0.0064 15.7 4.0 2.0 2 0 0 2 2 2 1 PHD-finger WHIM2 PF15613.1 KZN85780.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Rcd1 PF04078.8 KZN85781.1 - 6.5e-131 434.9 1.5 8e-131 434.6 1.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like POR_N PF01855.14 KZN85783.1 - 0.81 9.1 5.5 1.6 8.2 3.8 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HAD_2 PF13419.1 KZN85785.1 - 9.4e-21 74.8 0.1 1.6e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN85785.1 - 6.5e-05 22.5 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN85785.1 - 0.031 14.6 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DIOX_N PF14226.1 KZN85786.1 - 6.2e-28 97.6 0.0 9.9e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN85786.1 - 1.7e-18 66.7 0.0 3.3e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sld5 PF05916.6 KZN85787.1 - 6e-12 45.8 0.0 9.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.15 KZN85788.1 - 1.1e-41 142.7 8.7 2.1e-41 141.7 6.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KZN85788.1 - 7.9e-16 57.6 0.0 1.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KZN85788.1 - 2.9e-12 46.0 0.1 5.4e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 STAS domain BRCT PF00533.21 KZN85790.1 - 3.6e-33 113.5 0.0 3.3e-09 36.7 0.0 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KZN85790.1 - 7.5e-31 105.7 1.5 1.1e-19 70.0 0.3 5.7 5 1 0 5 5 5 4 twin BRCT domain ESCRT-II PF05871.7 KZN85791.1 - 1.7e-51 173.8 0.0 2.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 KZN85792.1 - 5e-48 162.7 0.0 2.3e-35 121.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KZN85792.1 - 5.8e-05 23.6 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN85792.1 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KZN85792.1 - 0.0018 17.3 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_26 PF13659.1 KZN85792.1 - 0.0052 16.8 0.0 0.016 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KZN85792.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN85792.1 - 0.015 14.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KZN85792.1 - 0.018 15.3 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85792.1 - 0.023 15.1 0.0 0.92 10.0 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85792.1 - 0.039 13.5 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LIM PF00412.17 KZN85793.1 - 3.6e-26 91.0 26.2 2.3e-10 40.3 2.5 3.8 3 1 0 3 3 3 3 LIM domain MFS_1 PF07690.11 KZN85794.1 - 6.9e-24 84.2 44.7 2.3e-23 82.4 31.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily RNB PF00773.14 KZN85795.1 - 1.4e-95 320.3 0.0 2e-95 319.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KZN85795.1 - 2.7e-07 30.7 0.4 1.3e-06 28.5 0.1 2.3 2 1 0 2 2 2 1 PIN domain CN_hydrolase PF00795.17 KZN85796.1 - 3e-26 91.9 0.0 5.6e-26 91.0 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ESSS PF10183.4 KZN85797.1 - 2.8e-31 108.0 0.1 3.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 KZN85797.1 - 0.73 9.4 3.4 1.2 8.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Dna2 PF08696.6 KZN85798.1 - 1.4e-68 230.3 0.2 2.3e-68 229.6 0.2 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KZN85798.1 - 3.4e-50 170.2 0.0 5.1e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN85798.1 - 9e-41 139.9 0.2 1e-19 71.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KZN85798.1 - 2.6e-14 53.2 0.0 5.8e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN85798.1 - 9.7e-12 44.4 0.1 3.4e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 KZN85798.1 - 2.6e-11 43.3 0.3 6.9e-11 42.0 0.1 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 KZN85798.1 - 4.6e-07 29.8 0.1 1.3e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KZN85798.1 - 3.4e-05 23.4 0.7 0.38 10.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KZN85798.1 - 0.00014 21.2 0.1 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KZN85798.1 - 0.00017 21.3 0.0 0.00035 20.2 0.0 1.5 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 KZN85798.1 - 0.00038 19.9 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KZN85798.1 - 0.00081 19.1 0.1 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KZN85798.1 - 0.0011 18.4 0.5 0.002 17.6 0.1 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain DUF911 PF06023.7 KZN85798.1 - 0.0014 17.9 0.1 0.003 16.8 0.1 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) AAA_16 PF13191.1 KZN85798.1 - 0.0018 18.3 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 KZN85798.1 - 0.005 15.8 0.2 0.026 13.4 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_25 PF13481.1 KZN85798.1 - 0.0099 15.2 0.0 0.032 13.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KZN85798.1 - 0.013 14.4 0.0 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KZN85798.1 - 0.042 13.3 0.1 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KZN85798.1 - 0.044 13.9 0.2 0.25 11.5 0.0 2.4 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KZN85798.1 - 0.045 13.6 0.6 0.73 9.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain ArgK PF03308.11 KZN85798.1 - 0.049 12.4 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 KZN85798.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 KZN85798.1 - 0.08 12.7 1.0 0.14 11.9 0.2 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA PF00004.24 KZN85798.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribonuc_P_40 PF08584.6 KZN85800.1 - 7.5e-84 281.0 0.0 9.8e-84 280.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 KZN85801.1 - 1.7e-34 116.4 9.3 8e-10 38.2 0.0 6.9 8 0 0 8 8 8 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KZN85801.1 - 5.6e-08 31.4 0.0 1.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 KZN85801.1 - 6.3e-05 22.7 0.1 0.14 11.8 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KZN85801.1 - 0.0017 17.7 0.0 0.033 13.6 0.0 3.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KZN85801.1 - 0.0026 15.9 0.3 0.046 11.8 0.0 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 KZN85801.1 - 0.023 14.4 0.3 1.2 8.7 0.0 3.2 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Fungal_trans PF04082.13 KZN85802.1 - 9e-19 67.3 0.1 1.6e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85802.1 - 1.2e-09 37.8 9.8 2.4e-09 36.9 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.13 KZN85803.1 - 1.8e-44 150.7 5.1 3.4e-32 110.9 0.2 2.8 3 0 0 3 3 3 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KZN85803.1 - 3.1e-25 87.9 0.1 5.7e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 KZN85804.1 - 1.8e-45 153.5 0.1 2.1e-44 150.1 0.0 2.2 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KZN85804.1 - 4.2e-35 120.2 0.1 7.4e-35 119.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain APH PF01636.18 KZN85805.1 - 1.6e-15 57.4 0.0 2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN85805.1 - 0.00083 18.9 0.0 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 KZN85805.1 - 0.028 13.5 0.0 0.083 12.0 0.0 1.7 1 1 1 2 2 2 0 Ecdysteroid kinase DUF1462 PF07315.6 KZN85805.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) HIT PF01230.18 KZN85806.1 - 5.8e-17 62.0 0.2 1.8e-16 60.4 0.1 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KZN85806.1 - 1.3e-05 25.3 0.0 2.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KZN85806.1 - 0.0029 17.2 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GluR_Homer-bdg PF10606.4 KZN85806.1 - 0.099 12.5 0.7 0.099 12.5 0.5 1.7 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor Methyltransf_26 PF13659.1 KZN85807.1 - 4.3e-11 42.8 0.0 9.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KZN85807.1 - 4.8e-09 36.0 0.0 9.4e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 KZN85807.1 - 0.07 12.6 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 DNA methylase N6_Mtase PF02384.11 KZN85807.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase SIR2 PF02146.12 KZN85808.1 - 6e-60 202.0 0.0 8.4e-60 201.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KZN85808.1 - 0.0008 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KZN85808.1 - 0.0029 17.3 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.1 KZN85809.1 - 2.4e-09 36.9 6.2 6e-08 32.5 0.2 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN85809.1 - 3.2e-09 36.0 0.9 0.0057 16.4 0.0 5.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN85809.1 - 6.6e-09 35.2 0.9 0.00016 21.2 0.1 4.5 3 2 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 KZN85809.1 - 1.9e-08 33.4 0.0 0.00086 18.9 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN85809.1 - 3.2e-08 34.0 9.0 0.002 18.7 0.4 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN85809.1 - 1.3e-07 31.8 15.2 3.7e-05 23.9 0.7 4.1 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN85809.1 - 1.9e-05 24.8 12.3 0.051 14.2 1.1 5.6 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN85809.1 - 3.2e-05 23.7 0.1 10 6.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN85809.1 - 0.00013 21.4 0.4 0.057 13.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN85809.1 - 0.0003 20.8 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KZN85809.1 - 0.00052 19.6 3.8 0.27 11.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN85809.1 - 0.0018 18.1 11.0 0.36 10.7 0.2 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KZN85809.1 - 0.011 16.1 0.4 0.011 16.1 0.3 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 KZN85809.1 - 0.018 14.1 3.3 0.021 13.9 0.2 2.5 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 KZN85809.1 - 0.022 14.6 2.6 0.048 13.5 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN85809.1 - 0.14 12.1 4.4 0.23 11.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN85809.1 - 0.41 11.2 10.7 17 6.1 0.3 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RWD PF05773.17 KZN85810.1 - 1.8e-22 79.3 0.1 1.8e-22 79.3 0.1 1.6 2 0 0 2 2 2 1 RWD domain RNase_H2-Ydr279 PF09468.5 KZN85810.1 - 0.23 10.6 6.4 0.32 10.1 4.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Complex1_LYR_1 PF13232.1 KZN85811.1 - 2.5e-15 56.4 0.4 2.2e-14 53.4 0.0 2.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KZN85811.1 - 3.6e-14 52.2 0.0 1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) POM121 PF15229.1 KZN85811.1 - 0.02 14.3 4.4 0.033 13.6 3.0 1.4 1 0 0 1 1 1 0 POM121 family UQ_con PF00179.21 KZN85812.1 - 2.8e-17 62.4 0.0 3.2e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN85812.1 - 0.015 15.1 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 KZN85813.1 - 1.1e-40 138.8 4.1 1.8e-40 138.1 0.0 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KZN85813.1 - 0.029 13.8 1.2 0.33 10.4 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) Ipi1_N PF12333.3 KZN85813.1 - 2.2 8.3 7.4 1.1 9.2 0.0 4.2 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Vps26 PF03643.10 KZN85814.1 - 4.4e-129 429.1 0.2 5.4e-129 428.8 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KZN85814.1 - 0.00046 20.0 0.5 1 9.2 0.0 3.2 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain SKI PF01202.17 KZN85815.1 - 1.8e-12 47.3 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KZN85815.1 - 2.7e-09 37.0 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN85815.1 - 6e-08 33.5 0.0 7.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN85815.1 - 1.5e-07 31.7 0.0 5.3e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KZN85815.1 - 0.0025 16.5 0.0 0.004 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KZN85815.1 - 0.022 14.9 0.0 0.06 13.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 KZN85815.1 - 0.037 13.2 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN85815.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KZN85815.1 - 0.046 14.0 0.2 0.075 13.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF4313 PF14190.1 KZN85815.1 - 0.053 13.2 0.1 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) AAA PF00004.24 KZN85815.1 - 0.073 13.2 0.1 0.19 11.9 0.0 1.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.15 KZN85815.1 - 0.082 12.3 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_14 PF13173.1 KZN85815.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 KZN85815.1 - 0.12 11.7 0.1 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.1 KZN85815.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain 2-oxoacid_dh PF00198.18 KZN85816.1 - 4.6e-79 264.9 0.2 6.8e-79 264.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KZN85816.1 - 1.3e-13 50.3 0.0 3.2e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KZN85816.1 - 2.1e-12 46.4 0.9 5.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain COesterase PF00135.23 KZN85817.1 - 2.7e-83 280.4 3.8 4.5e-83 279.7 2.7 1.3 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KZN85817.1 - 0.00015 21.0 0.2 0.00034 19.9 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KZN85817.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PI-PLC-X PF00388.14 KZN85818.1 - 3.6e-10 39.4 0.0 1.1e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 KZN85819.1 - 0.033 14.1 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 Glycos_transf_3 PF00591.16 KZN85820.1 - 8.7e-60 202.2 0.0 1.8e-57 194.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KZN85820.1 - 3e-07 29.9 0.4 7.7e-07 28.6 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 KZN85821.1 - 8.3e-17 60.3 5.2 1.1e-16 60.0 3.6 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 KZN85821.1 - 0.00047 20.0 0.9 0.078 12.9 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.14 KZN85821.1 - 0.0012 18.4 0.1 0.0014 18.3 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KZN85821.1 - 0.0025 17.5 0.2 0.0036 17.0 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 KZN85821.1 - 0.0056 16.1 1.5 0.07 12.6 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain GFA PF04828.9 KZN85821.1 - 0.06 13.2 0.5 0.41 10.6 0.3 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 KZN85821.1 - 0.078 12.9 0.9 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2318 PF10080.4 KZN85821.1 - 0.08 12.7 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIS_C PF01096.13 KZN85821.1 - 0.1 12.2 0.7 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Ribosomal_L40e PF01020.12 KZN85821.1 - 0.13 11.9 2.9 0.18 11.3 2.0 1.2 1 0 0 1 1 1 0 Ribosomal L40e family UPF0547 PF10571.4 KZN85821.1 - 0.16 11.7 1.7 0.46 10.2 1.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 KZN85821.1 - 0.27 10.7 3.3 3.1 7.3 0.1 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_4 PF13717.1 KZN85821.1 - 1.2 8.9 3.8 5.2 6.8 2.7 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KZN85821.1 - 1.4 8.5 3.9 5.5 6.6 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Fe_hyd_lg_C PF02906.9 KZN85822.1 - 2.2e-59 201.0 0.0 3.8e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 KZN85823.1 - 1.3e-26 93.4 0.0 2.7e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KZN85823.1 - 0.028 14.3 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Macro domain Fapy_DNA_glyco PF01149.19 KZN85825.1 - 4.3e-27 94.7 0.0 7.6e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KZN85825.1 - 1.3e-21 76.1 0.0 2.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KZN85825.1 - 0.0023 16.5 0.0 0.013 14.0 0.0 1.9 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Cid2 PF09774.4 KZN85826.1 - 4.1e-52 176.2 0.3 5.1e-52 175.9 0.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 KZN85827.1 - 4.3e-214 712.0 17.7 7.5e-212 704.6 8.2 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KZN85827.1 - 2.1e-20 72.8 19.8 0.0042 17.3 0.8 7.8 6 2 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KZN85827.1 - 2.4e-18 66.2 17.3 0.00051 20.6 0.5 8.6 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN85827.1 - 3.9e-18 64.8 22.0 1.1e-06 28.1 0.1 7.3 7 1 0 7 7 7 4 TPR repeat TPR_14 PF13428.1 KZN85827.1 - 4.8e-18 64.0 17.6 0.013 16.1 0.1 11.3 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 KZN85827.1 - 3.5e-16 57.7 24.4 0.00035 20.2 0.1 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KZN85827.1 - 5.4e-10 38.4 19.9 9.3e-05 21.8 0.1 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN85827.1 - 4.6e-07 29.6 16.6 0.023 14.6 0.2 7.2 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN85827.1 - 7.7e-07 28.8 12.5 2.7 8.4 0.1 7.6 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN85827.1 - 6.9e-06 25.8 8.5 0.0017 18.1 1.6 5.3 4 3 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KZN85827.1 - 1.7e-05 24.2 9.4 0.011 15.4 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN85827.1 - 0.00015 21.8 18.4 0.13 12.4 0.2 6.7 4 3 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3087 PF11286.3 KZN85827.1 - 0.0022 17.2 2.1 0.16 11.1 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3087) TPR_3 PF07720.7 KZN85827.1 - 0.0098 15.6 0.1 0.16 11.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KZN85827.1 - 0.013 15.9 18.5 3.7 8.2 0.1 7.4 9 0 0 9 9 6 0 Tetratricopeptide repeat MIT PF04212.13 KZN85827.1 - 0.03 14.1 0.1 0.03 14.1 0.1 4.5 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 KZN85827.1 - 0.043 13.6 6.9 12 5.8 0.0 5.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KZN85827.1 - 0.15 11.9 7.4 4.9 7.1 0.0 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN85827.1 - 0.84 10.2 13.7 0.17 12.4 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Tim54 PF11711.3 KZN85828.1 - 1.2e-145 484.9 0.2 1.4e-145 484.7 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Tyrosinase PF00264.15 KZN85829.1 - 5.9e-25 88.7 1.7 8.4e-25 88.2 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2573 PF10835.3 KZN85829.1 - 0.0075 16.2 0.0 0.32 11.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2573) HD PF01966.17 KZN85830.1 - 0.00021 21.2 0.1 0.00039 20.4 0.0 1.6 1 1 0 1 1 1 1 HD domain Glyco_hydro_20 PF00728.17 KZN85831.1 - 2.5e-33 115.7 0.0 2.7e-21 76.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain AIG2 PF06094.7 KZN85831.1 - 2.9e-06 27.6 0.0 4.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Pkinase PF00069.20 KZN85832.1 - 1.4e-53 181.6 0.1 2.7e-37 128.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85832.1 - 2.2e-24 85.9 0.4 3.3e-19 68.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KZN85832.1 - 5.8e-05 22.1 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN85832.1 - 0.00018 20.6 0.0 0.00037 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN85832.1 - 0.0004 20.1 2.2 0.0038 16.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN85832.1 - 0.0064 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 KZN85832.1 - 0.016 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 KZN85832.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-met PF12874.2 KZN85833.1 - 3.6e-05 23.8 1.9 3.6e-05 23.7 0.4 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KZN85833.1 - 0.048 12.9 0.9 0.092 12.0 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.20 KZN85834.1 - 8.8e-20 70.1 0.3 1.4e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 KZN85834.1 - 2.9e-13 49.3 7.0 6.3e-08 32.2 0.4 3.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KZN85834.1 - 3.8e-13 48.7 14.7 6.7e-05 22.4 0.1 5.5 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KZN85834.1 - 2.3e-07 29.8 10.3 0.43 10.7 0.4 7.4 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KZN85834.1 - 5.2e-07 29.0 12.9 0.84 9.8 0.2 8.1 7 2 1 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 KZN85834.1 - 0.00073 19.3 12.2 3.8 8.1 0.1 7.2 9 0 0 9 9 9 2 Leucine rich repeat CK2S PF15011.1 KZN85834.1 - 0.085 12.6 0.4 1.6 8.5 0.0 2.3 1 1 1 2 2 2 0 Casein Kinase 2 substrate LRR_9 PF14580.1 KZN85834.1 - 0.21 11.1 1.5 6.5 6.2 0.1 2.9 1 1 2 3 3 3 0 Leucine-rich repeat Zn_clus PF00172.13 KZN85836.1 - 6.3e-08 32.4 8.8 6.3e-08 32.4 6.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 KZN85837.1 - 1e-05 24.9 0.1 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 KZN85837.1 - 1.6e-05 24.5 0.1 4e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Coiled coil protein 84 2-Hacid_dh_C PF02826.14 KZN85838.1 - 1.7e-58 196.6 0.0 2.4e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN85838.1 - 8.9e-15 54.3 0.0 1.2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN85838.1 - 0.00016 21.5 0.3 0.00036 20.4 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KZN85838.1 - 0.01 15.1 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KZN85838.1 - 0.074 12.8 0.2 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 KZN85838.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CwfJ_C_1 PF04677.10 KZN85839.1 - 4.8e-29 100.4 0.0 3.8e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KZN85839.1 - 1.2e-23 83.3 0.0 3.9e-23 81.7 0.0 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF1777 PF08648.7 KZN85839.1 - 5.9e-05 22.8 35.0 5.9e-05 22.8 24.3 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) ATP_bind_1 PF03029.12 KZN85840.1 - 9.4e-77 257.7 0.0 1.2e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KZN85840.1 - 3.2e-05 23.4 0.0 0.00059 19.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KZN85840.1 - 0.00014 20.7 0.0 0.07 11.8 0.0 2.4 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 KZN85840.1 - 0.0002 21.3 0.0 0.00054 19.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KZN85840.1 - 0.00029 20.9 0.0 0.00095 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KZN85840.1 - 0.0003 20.3 0.0 0.00048 19.6 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 KZN85840.1 - 0.0004 20.8 0.0 0.5 10.8 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KZN85840.1 - 0.00074 20.3 0.5 0.0031 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 KZN85840.1 - 0.0019 17.6 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PRK PF00485.13 KZN85840.1 - 0.003 17.1 0.0 0.066 12.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 KZN85840.1 - 0.0037 16.9 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KZN85840.1 - 0.0039 17.0 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Methyltransf_32 PF13679.1 KZN85840.1 - 0.0053 16.4 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FeoB_N PF02421.13 KZN85840.1 - 0.0056 15.9 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B MobB PF03205.9 KZN85840.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KZN85840.1 - 0.01 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN85840.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KZN85840.1 - 0.016 14.6 0.0 0.75 9.2 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 KZN85840.1 - 0.022 13.9 0.0 7.7 5.7 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 KZN85840.1 - 0.023 13.5 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CbiA PF01656.18 KZN85840.1 - 0.026 13.9 0.0 0.075 12.4 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 KZN85840.1 - 0.04 12.8 0.4 0.15 11.0 0.3 2.0 1 1 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.15 KZN85840.1 - 0.055 12.1 4.6 0.53 8.9 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.12 KZN85840.1 - 0.065 13.0 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 KZN85840.1 - 0.1 12.0 0.1 1.1 8.7 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KZN85840.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4395 PF14340.1 KZN85841.1 - 0.028 14.5 0.2 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) MarC PF01914.12 KZN85841.1 - 0.11 11.6 1.1 0.21 10.6 0.8 1.4 1 0 0 1 1 1 0 MarC family integral membrane protein GST_N_3 PF13417.1 KZN85842.1 - 7.3e-25 87.0 0.0 1.4e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN85842.1 - 1.3e-16 60.2 0.0 2.9e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN85842.1 - 1.1e-08 34.7 0.0 7.6e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN85842.1 - 6.5e-06 26.0 0.0 2.2e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN85842.1 - 0.001 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KZN85842.1 - 0.02 14.8 0.2 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin SUZ PF12752.2 KZN85843.1 - 0.0031 17.9 2.8 0.0031 17.9 2.0 4.8 2 1 1 3 3 3 1 SUZ domain SDH_beta PF03315.10 KZN85843.1 - 0.055 13.5 2.0 0.063 13.3 0.3 1.8 2 1 0 2 2 2 0 Serine dehydratase beta chain eIF3_subunit PF08597.5 KZN85843.1 - 2.6 7.5 8.9 1.7 8.1 1.7 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Aldo_ket_red PF00248.16 KZN85846.1 - 1.2e-57 194.9 0.0 1.4e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 KZN85847.1 - 2.5e-21 75.4 0.0 4.3e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN85847.1 - 1.6e-18 66.1 0.0 5.3e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KZN85847.1 - 0.0019 18.4 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN85847.1 - 0.007 16.7 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KZN85847.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Apt1 PF10351.4 KZN85847.1 - 0.058 12.2 0.0 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain LRR_4 PF12799.2 KZN85848.1 - 0.00017 21.1 7.6 0.15 11.7 0.3 4.9 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN85848.1 - 0.0027 17.4 4.6 0.21 11.3 0.1 4.3 3 2 3 6 6 6 1 Leucine rich repeat F-box-like PF12937.2 KZN85848.1 - 0.0032 17.1 0.0 0.0081 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 KZN85848.1 - 0.0089 15.9 3.3 24 5.4 0.0 6.0 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 KZN85848.1 - 0.017 15.1 6.3 1.3 9.3 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 KZN85848.1 - 0.073 13.3 3.5 42 4.9 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat tRNA-synt_1f PF01921.13 KZN85849.1 - 0.15 10.7 0.3 0.33 9.5 0.2 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (K) BSD PF03909.12 KZN85850.1 - 6.2e-25 86.7 7.5 1.1e-14 53.9 0.4 2.8 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KZN85850.1 - 5.3e-24 83.6 0.0 1.1e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Peptidase_C80 PF11713.3 KZN85850.1 - 0.03 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase C80 family DUF1751 PF08551.5 KZN85851.1 - 0.016 15.5 0.1 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) ING PF12998.2 KZN85852.1 - 9.5e-12 45.1 0.0 3e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KZN85852.1 - 1.6e-09 37.3 8.0 2.6e-09 36.6 5.5 1.3 1 0 0 1 1 1 1 PHD-finger DUF4378 PF14309.1 KZN85852.1 - 0.039 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) zf-HC5HC2H PF13771.1 KZN85852.1 - 0.082 13.0 0.6 0.18 12.0 0.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prp19 PF08606.6 KZN85852.1 - 1.5 8.5 5.1 6.5 6.5 1.3 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like Transket_pyr PF02779.19 KZN85853.1 - 1.2e-65 220.3 0.0 2.2e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KZN85853.1 - 5.2e-56 189.5 0.0 7.2e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component APH PF01636.18 KZN85856.1 - 7.4e-07 29.1 0.0 2.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KZN85856.1 - 0.0059 16.4 9.4 0.012 15.4 6.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Allatostatin PF05953.7 KZN85856.1 - 0.13 12.8 0.5 9.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Allatostatin DUF4066 PF13278.1 KZN85857.1 - 2e-27 95.4 0.1 2.4e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KZN85857.1 - 5.9e-08 32.2 0.0 8.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KZN85857.1 - 0.025 14.0 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Sld5 PF05916.6 KZN85858.1 - 4.9e-16 58.9 0.0 6.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Microtub_assoc PF07989.6 KZN85859.1 - 2.6 7.9 8.7 3.7 7.4 5.2 1.9 1 1 1 2 2 2 0 Microtubule associated DUF2502 PF10697.4 KZN85860.1 - 0.082 13.0 1.4 0.16 12.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) zf-C2H2_4 PF13894.1 KZN85860.1 - 0.26 11.7 2.9 0.73 10.3 2.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN85860.1 - 1.6 9.1 5.9 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF3039 PF11238.3 KZN85861.1 - 0.034 13.5 0.1 0.94 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) F-box-like PF12937.2 KZN85861.1 - 0.087 12.5 0.9 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 F-box-like Sod_Fe_C PF02777.13 KZN85862.1 - 1.7e-38 130.6 0.8 2.7e-38 130.0 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KZN85862.1 - 1.3e-29 102.2 2.0 2.2e-29 101.5 1.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KZN85862.1 - 0.076 12.1 5.0 0.35 9.9 0.1 3.4 2 2 2 4 4 4 0 Immunity protein 15 GCFC PF07842.7 KZN85863.1 - 5.4e-84 281.8 5.4 9.1e-84 281.0 3.8 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KZN85863.1 - 2.2e-17 62.5 0.8 5.1e-17 61.3 0.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KZN85863.1 - 3.6e-08 33.1 0.4 3.6e-08 33.1 0.3 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site DHC_N1 PF08385.7 KZN85863.1 - 0.0027 16.1 0.8 0.0042 15.5 0.5 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Draxin PF15550.1 KZN85863.1 - 0.28 10.7 5.1 0.47 10.0 3.6 1.3 1 0 0 1 1 1 0 Draxin VIT1 PF01988.14 KZN85864.1 - 2.7e-58 196.9 7.3 3.2e-58 196.7 5.0 1.0 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 KZN85864.1 - 0.26 10.5 1.2 0.38 10.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4202 PF13875.1 KZN85865.1 - 1.4e-79 266.0 0.4 1.6e-79 265.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) PAM2 PF07145.10 KZN85865.1 - 0.18 11.3 0.3 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Sugar_tr PF00083.19 KZN85866.1 - 7.4e-79 265.4 22.7 9.2e-79 265.1 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85866.1 - 6.2e-24 84.3 22.5 6.2e-24 84.3 15.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KZN85866.1 - 0.00064 17.9 3.1 0.0065 14.6 0.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Caps_synth PF05704.7 KZN85866.1 - 0.086 11.9 0.1 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Cation_efflux PF01545.16 KZN85867.1 - 3.1e-41 141.3 2.0 3.6e-41 141.1 1.4 1.0 1 0 0 1 1 1 1 Cation efflux family DUF3848 PF12959.2 KZN85867.1 - 0.027 14.4 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) DUF1700 PF08006.6 KZN85867.1 - 0.1 11.8 3.1 0.059 12.6 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) p450 PF00067.17 KZN85868.1 - 7.7e-53 179.6 0.0 9.8e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rox3 PF08633.5 KZN85869.1 - 2.8e-51 174.6 0.2 2.8e-51 174.6 0.2 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit Fungal_trans PF04082.13 KZN85870.1 - 3e-17 62.3 0.0 4.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85870.1 - 1.3e-09 37.7 11.4 2.2e-09 37.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN85871.1 - 3.1e-23 81.9 0.1 4.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN85871.1 - 3.8e-08 33.0 8.2 3.8e-08 33.0 5.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhnA PF03831.9 KZN85872.1 - 0.23 10.8 3.1 0.4 10.1 1.3 2.0 2 0 0 2 2 2 0 PhnA protein BRI3BP PF14965.1 KZN85872.1 - 0.68 9.2 6.3 9.1 5.6 0.0 3.7 4 0 0 4 4 4 0 Negative regulator of p53/TP53 Beta-APP PF03494.8 KZN85873.1 - 0.088 12.2 0.3 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) MFS_1 PF07690.11 KZN85874.1 - 5.4e-39 133.9 27.6 8.5e-39 133.2 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85874.1 - 4.9e-12 45.1 26.3 2.5e-11 42.8 5.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 KZN85874.1 - 1.8e-07 29.7 3.0 1.8e-07 29.7 2.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1625 PF07787.7 KZN85876.1 - 4.6 6.4 5.7 6.9 5.8 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) dCMP_cyt_deam_1 PF00383.17 KZN85877.1 - 1.9e-11 43.5 0.1 2.6e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KZN85877.1 - 0.026 14.3 2.1 0.09 12.6 0.3 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase DUF4449 PF14613.1 KZN85878.1 - 2.7e-63 212.7 0.1 2.7e-63 212.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) AIRC PF00731.15 KZN85879.1 - 7.1e-59 197.3 1.9 1.4e-58 196.4 1.3 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KZN85879.1 - 1.1e-52 177.8 0.0 2.3e-52 176.8 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KZN85879.1 - 8.8e-12 45.1 0.0 1.3e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KZN85879.1 - 1.1e-06 28.1 0.0 2.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 KZN85879.1 - 0.00016 21.1 0.0 0.0025 17.2 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KZN85879.1 - 0.0038 16.0 0.0 0.11 11.2 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.1 KZN85879.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_M15_3 PF08291.6 KZN85879.1 - 0.029 14.1 0.0 0.48 10.2 0.0 2.8 2 1 0 3 3 3 0 Peptidase M15 2-Hacid_dh_C PF02826.14 KZN85879.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 KZN85879.1 - 0.11 12.7 0.5 21 5.3 0.1 3.3 2 1 1 3 3 3 0 CoA binding domain PPP4R2 PF09184.6 KZN85880.1 - 1.6e-10 41.0 0.0 1.6e-10 41.0 0.0 2.6 2 1 0 3 3 3 1 PPP4R2 HSF_DNA-bind PF00447.12 KZN85881.1 - 3.9e-38 129.7 0.4 7.6e-38 128.8 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KZN85881.1 - 1.9e-21 76.1 0.0 3.7e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CENP-Q PF13094.1 KZN85881.1 - 0.0062 16.5 5.1 0.0062 16.5 3.5 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 KZN85881.1 - 0.029 14.7 6.7 0.12 12.7 4.6 2.1 1 0 0 1 1 1 0 SlyX Clusterin PF01093.12 KZN85881.1 - 0.034 12.9 2.0 0.053 12.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin DivIC PF04977.10 KZN85881.1 - 0.14 11.6 2.0 0.27 10.7 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KZN85881.1 - 0.15 11.6 2.5 0.24 10.9 1.8 1.2 1 0 0 1 1 1 0 IncA protein Redoxin PF08534.5 KZN85882.1 - 5.4e-27 94.1 0.0 6.2e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KZN85882.1 - 8.9e-09 35.0 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.13 KZN85883.1 - 6.4e-23 80.5 0.0 1.3e-22 79.5 0.0 1.5 2 0 0 2 2 2 1 BolA-like protein Ribosomal_L13e PF01294.13 KZN85883.1 - 0.05 13.0 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e NIF3 PF01784.13 KZN85884.1 - 8.4e-56 189.2 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ENTH PF01417.15 KZN85885.1 - 7e-48 161.6 0.0 1.5e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KZN85885.1 - 0.0014 17.4 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 KZN85885.1 - 0.0064 15.9 4.0 0.012 15.0 0.5 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.1 KZN85885.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) ADP_ribosyl_GH PF03747.9 KZN85886.1 - 5.8e-56 190.3 0.0 7e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Chorismate_bind PF00425.13 KZN85887.1 - 1.7e-89 299.5 0.0 2.3e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KZN85887.1 - 4.1e-30 104.6 0.1 3.5e-27 95.1 0.0 2.8 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region WD40 PF00400.27 KZN85888.1 - 5.9e-07 29.1 6.0 0.0079 16.0 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat LisH PF08513.6 KZN85888.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KZN85888.1 - 0.00028 20.6 0.0 0.00099 18.8 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1751 PF08551.5 KZN85889.1 - 1.4e-28 99.0 2.8 1.4e-28 99.0 1.9 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KZN85889.1 - 0.0033 17.4 9.0 0.0085 16.1 6.2 1.7 1 1 0 1 1 1 1 Rhomboid family UPF0197 PF05251.7 KZN85890.1 - 0.5 10.7 8.4 0.46 10.8 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0197) DUF2721 PF11026.3 KZN85890.1 - 3.1 7.4 5.7 3.5 7.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Bromodomain PF00439.20 KZN85891.1 - 1.5e-24 85.7 0.4 2.8e-24 84.8 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KZN85891.1 - 1.2e-09 38.1 0.1 2.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN85891.1 - 5.1e-09 36.0 0.0 9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RGS PF00615.14 KZN85892.1 - 2.4e-11 43.7 0.0 2.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain NMN_transporter PF04973.7 KZN85892.1 - 0.084 12.3 2.8 0.15 11.5 2.0 1.4 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter PCI PF01399.22 KZN85893.1 - 7.2e-06 26.2 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF1192 PF06698.6 KZN85893.1 - 0.35 10.6 3.1 0.54 10.0 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) E1-E2_ATPase PF00122.15 KZN85894.1 - 1.2e-49 168.4 0.2 2.9e-49 167.2 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 KZN85894.1 - 2e-44 149.5 0.0 7.1e-11 42.0 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KZN85894.1 - 2.9e-44 152.0 0.7 6.2e-44 150.9 0.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN85894.1 - 6.8e-14 52.4 0.0 2e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN85894.1 - 2.4e-05 24.0 0.8 0.00026 20.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase W2 PF02020.13 KZN85895.1 - 1.9e-14 53.3 17.2 1.9e-14 53.3 11.9 2.7 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KZN85895.1 - 8.8e-08 31.3 19.2 3.3e-05 23.1 0.6 4.9 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KZN85895.1 - 3.1e-07 29.9 0.0 5.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KZN85895.1 - 4.1e-05 23.0 15.9 0.011 15.2 0.1 4.2 1 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KZN85895.1 - 0.00064 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain SpoIIID PF12116.3 KZN85896.1 - 0.026 14.4 0.5 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D VCX_VCY PF15231.1 KZN85896.1 - 0.2 12.0 10.9 0.23 11.8 7.6 1.1 1 0 0 1 1 1 0 Variable charge X/Y family MAGE_N PF12440.3 KZN85896.1 - 0.2 11.9 5.9 0.29 11.4 4.1 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF605 PF04652.11 KZN85896.1 - 5.5 6.2 9.2 6.2 6.1 6.4 1.0 1 0 0 1 1 1 0 Vta1 like IBR PF01485.16 KZN85897.1 - 1.1e-22 79.6 44.0 4.3e-12 45.7 4.1 4.5 3 1 1 4 4 4 4 IBR domain zf-C3HC4_2 PF13923.1 KZN85897.1 - 7e-06 25.9 6.5 7e-06 25.9 4.5 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN85897.1 - 2.4e-05 24.0 4.7 2.4e-05 24.0 3.2 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KZN85897.1 - 0.00018 21.0 4.3 0.00018 21.0 3.0 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN85897.1 - 0.0027 17.3 7.2 0.0027 17.3 5.0 4.0 2 1 1 3 3 3 1 zinc-RING finger domain UN_NPL4 PF11543.3 KZN85897.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.1 KZN85897.1 - 0.0081 15.8 1.6 0.0081 15.8 1.1 3.5 3 0 0 3 3 3 1 RING-type zinc-finger AceK PF06315.6 KZN85897.1 - 0.036 12.3 0.3 0.049 11.9 0.2 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-C3HC4_4 PF15227.1 KZN85897.1 - 0.11 12.3 0.3 0.11 12.3 0.2 4.6 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.22 KZN85898.1 - 3.1e-69 228.7 7.0 3.4e-25 87.5 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein O-antigen_lig PF13425.1 KZN85898.1 - 0.072 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 O-antigen ligase like membrane protein AAA PF00004.24 KZN85899.1 - 2.1e-38 131.5 0.0 4.1e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KZN85899.1 - 7.3e-07 28.9 0.0 2.3e-05 24.2 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KZN85899.1 - 3.2e-06 27.3 0.4 4.3e-05 23.6 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KZN85899.1 - 3.9e-05 23.6 0.0 7.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KZN85899.1 - 7e-05 21.9 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN85899.1 - 0.00054 19.7 0.1 0.002 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KZN85899.1 - 0.00077 18.2 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 KZN85899.1 - 0.0011 18.5 0.1 0.0034 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KZN85899.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KZN85899.1 - 0.0026 16.9 0.1 0.0055 15.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KZN85899.1 - 0.0031 17.2 0.2 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KZN85899.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN85899.1 - 0.0043 17.0 0.4 0.0043 17.0 0.3 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KZN85899.1 - 0.0059 16.0 0.2 0.091 12.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KZN85899.1 - 0.0066 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KZN85899.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN85899.1 - 0.015 16.1 0.5 0.046 14.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KZN85899.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KZN85899.1 - 0.057 12.8 0.0 0.23 10.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 KZN85899.1 - 0.06 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase NACHT PF05729.7 KZN85899.1 - 0.069 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 KZN85899.1 - 0.073 13.0 0.7 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KZN85899.1 - 0.091 13.0 0.0 0.53 10.5 0.0 2.3 2 1 0 2 2 2 0 ABC transporter PhoH PF02562.11 KZN85899.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein COG6 PF06419.6 KZN85900.1 - 4.1e-243 808.0 0.3 4.6e-243 807.8 0.2 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.8 KZN85900.1 - 0.017 14.7 0.8 0.041 13.5 0.6 1.7 1 0 0 1 1 1 0 Transcriptional activator COG2 PF06148.6 KZN85900.1 - 0.022 14.6 2.8 0.044 13.6 0.8 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Shugoshin_N PF07558.6 KZN85900.1 - 0.087 12.5 0.2 0.31 10.7 0.1 1.9 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Laminin_II PF06009.7 KZN85900.1 - 0.099 12.4 1.4 0.27 11.0 0.9 1.7 1 0 0 1 1 1 0 Laminin Domain II Tnp_DNA_bind PF14706.1 KZN85900.1 - 0.1 12.3 0.1 0.32 10.7 0.1 1.9 1 0 0 1 1 1 0 Transposase DNA-binding Syntaxin-6_N PF09177.6 KZN85901.1 - 0.065 13.6 6.1 17 5.9 1.5 3.6 2 1 2 4 4 4 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 KZN85901.1 - 0.1 11.0 1.9 0.084 11.3 0.3 1.5 1 1 1 2 2 2 0 AAA domain Alpha-E PF04168.7 KZN85901.1 - 2.8 7.2 7.2 10 5.3 2.1 2.4 1 1 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. NYN PF01936.13 KZN85902.1 - 0.00093 19.5 0.0 0.012 15.9 0.0 2.6 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 KZN85903.1 - 2e-25 88.6 8.6 3.5e-25 87.8 6.0 1.4 1 0 0 1 1 1 1 Heat shock protein 9/12 YtxH PF12732.2 KZN85903.1 - 2.1 8.7 4.6 2.2 8.7 2.7 1.5 1 1 0 1 1 1 0 YtxH-like protein Tombus_movement PF05318.7 KZN85903.1 - 3.8 8.1 5.6 2.8 8.6 3.1 1.3 1 1 0 1 1 1 0 Tombusvirus movement protein Mog1 PF04603.7 KZN85904.1 - 2.3e-12 47.0 0.1 3e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 Ran-interacting Mog1 protein SET PF00856.23 KZN85905.1 - 3.5e-09 37.1 0.0 1.9e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 SET domain adh_short PF00106.20 KZN85906.1 - 1.3e-23 83.7 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN85906.1 - 1.7e-11 44.3 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN85906.1 - 2.4e-07 30.6 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KZN85906.1 - 9.7e-06 24.7 0.1 1.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN85906.1 - 3.4e-05 23.9 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KZN85906.1 - 0.00013 22.0 0.1 0.00026 21.0 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 KZN85906.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 KZN85906.1 - 0.031 14.0 1.0 0.071 12.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KZN85906.1 - 0.055 12.3 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 KZN85906.1 - 0.067 12.6 0.1 0.31 10.4 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SprT-like PF10263.4 KZN85907.1 - 1.8e-34 118.6 2.0 2.6e-34 118.1 1.4 1.3 1 0 0 1 1 1 1 SprT-like family Pkinase PF00069.20 KZN85908.1 - 2.9e-11 43.0 0.0 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85908.1 - 8.9e-08 31.5 0.1 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN85908.1 - 4e-07 30.0 0.1 5.4e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN85908.1 - 1.6e-05 24.0 0.1 2.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KZN85908.1 - 0.0012 18.4 0.2 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 KZN85908.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 KZN85908.1 - 0.078 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Glucan_synthase PF02364.10 KZN85909.1 - 0 1488.5 0.0 0 1487.8 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KZN85909.1 - 8.3e-40 135.3 0.5 1.9e-39 134.1 0.3 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KZN85910.1 - 3.9e-40 137.9 0.0 4.5e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KZN85910.1 - 0.014 13.6 0.0 0.028 12.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 KZN85911.1 - 1.4e-06 27.6 0.0 0.00021 20.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 WD40 PF00400.27 KZN85913.1 - 3.9e-16 58.2 1.3 0.00045 19.9 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat RasGAP PF00616.14 KZN85914.1 - 2.4e-44 151.3 0.0 5.5e-44 150.1 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KZN85914.1 - 9.3e-07 28.6 0.0 2.5e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain APG9 PF04109.11 KZN85915.1 - 2e-169 563.3 2.6 2.5e-169 563.0 1.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 KZN85916.1 - 1.3e-177 591.0 0.0 1.6e-177 590.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 KZN85917.1 - 5.9e-52 175.1 0.3 5.9e-52 175.1 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) COQ9 PF08511.6 KZN85918.1 - 1.2e-20 72.7 0.1 2.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 KZN85919.1 - 1.1e-49 165.9 0.0 1.3e-17 63.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN85919.1 - 1.7e-40 136.8 0.0 2.5e-15 56.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN85919.1 - 1.9e-21 75.6 0.0 1.3e-07 31.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN85919.1 - 0.0018 18.0 0.0 7.9 6.3 0.0 3.5 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 KZN85919.1 - 0.0022 17.7 0.1 14 5.5 0.0 4.1 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 KZN85919.1 - 0.087 12.1 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain PH PF00169.24 KZN85920.1 - 2.3e-10 40.5 1.6 6.3e-10 39.1 0.1 2.3 2 1 0 2 2 2 1 PH domain Tim17 PF02466.14 KZN85921.1 - 5.1e-13 49.1 7.7 8.2e-13 48.5 5.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 KZN85922.1 - 4.1e-50 170.4 0.0 6.9e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KZN85922.1 - 7.2e-46 153.4 0.1 1.1e-20 72.7 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KZN85922.1 - 1.5e-11 44.3 1.1 1.3e-06 28.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 KZN85922.1 - 0.077 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 PUB domain CoA_trans PF01144.18 KZN85923.1 - 2e-100 334.4 1.1 2e-59 200.3 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.4 KZN85925.1 - 4.9e-88 294.4 0.5 9.5e-88 293.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.3 KZN85925.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3632 PF12311.3 KZN85926.1 - 1.9e-43 148.4 6.4 2.5e-43 148.0 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Rb_C PF08934.5 KZN85927.1 - 0.19 11.3 5.5 0.032 13.8 0.8 1.9 2 0 0 2 2 2 0 Rb C-terminal domain Cu-oxidase_3 PF07732.10 KZN85928.1 - 6.8e-09 35.4 0.0 7.6e-08 32.1 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN85928.1 - 5.8e-05 22.6 0.4 0.0012 18.3 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Pkinase PF00069.20 KZN85930.1 - 5.5e-71 238.7 0.0 7.1e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85930.1 - 7.1e-31 107.2 0.0 1.1e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN85930.1 - 0.044 13.5 2.1 0.058 13.1 0.1 2.2 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KZN85930.1 - 0.084 11.9 0.0 0.23 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN85931.1 - 7.8e-19 67.8 0.0 4.7e-18 65.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN85931.1 - 1.1e-08 34.5 0.0 0.0016 17.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KZN85931.1 - 0.012 15.3 0.3 0.089 12.5 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN85931.1 - 0.087 11.7 0.1 6.1 5.7 0.0 2.3 3 0 0 3 3 3 0 Kinase-like tRNA-synt_2b PF00587.20 KZN85933.1 - 1.1e-41 142.2 0.0 1.9e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KZN85933.1 - 1.3e-16 60.3 0.2 3e-16 59.1 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KZN85933.1 - 4.6e-14 52.0 0.0 8.8e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KZN85933.1 - 2.3e-06 27.3 0.0 5.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 KZN85934.1 - 1.4e-42 144.7 1.6 6e-42 142.7 1.1 1.8 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 KZN85935.1 - 5.8e-11 42.6 0.9 5.8e-11 42.6 0.6 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WSC PF01822.14 KZN85936.1 - 1.5e-13 50.4 10.5 1.5e-13 50.4 7.3 2.4 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 KZN85936.1 - 7.9e-08 31.4 2.0 7.9e-08 31.4 1.4 2.1 2 0 0 2 2 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KZN85936.1 - 0.00059 19.4 1.8 0.0011 18.5 1.2 1.4 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.1 KZN85936.1 - 0.0047 16.3 0.2 0.0087 15.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Sporozoite_P67 PF05642.6 KZN85936.1 - 0.012 13.5 7.9 0.014 13.2 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4448 PF14610.1 KZN85936.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2165 PF09933.4 KZN85936.1 - 0.071 12.8 0.7 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Plasmodium_Vir PF05795.6 KZN85936.1 - 0.079 12.1 0.2 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SCHIP-1 PF10148.4 KZN85936.1 - 0.2 11.0 2.7 0.3 10.4 1.9 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 DLIC PF05783.6 KZN85936.1 - 3.3 6.2 7.7 5.7 5.4 5.3 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Macoilin PF09726.4 KZN85936.1 - 4.1 5.5 6.3 5.6 5.1 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Papilloma_E5A PF05776.7 KZN85937.1 - 0.21 11.7 2.9 0.33 11.1 2.0 1.2 1 0 0 1 1 1 0 Papillomavirus E5A protein zf-C2H2_4 PF13894.1 KZN85938.1 - 1.3e-07 31.4 10.9 2.6e-05 24.2 2.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN85938.1 - 3.8e-06 26.9 10.4 0.0016 18.6 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN85938.1 - 2.3 8.6 14.4 1.4 9.3 2.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain G_glu_transpept PF01019.16 KZN85939.1 - 3.1e-142 474.6 0.0 3.9e-142 474.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Clusterin PF01093.12 KZN85940.1 - 0.046 12.5 0.9 0.065 12.0 0.6 1.2 1 0 0 1 1 1 0 Clusterin FYVE PF01363.16 KZN85940.1 - 0.34 10.8 13.7 3.4 7.6 9.3 2.6 1 1 0 1 1 1 0 FYVE zinc finger FYVE_2 PF02318.11 KZN85940.1 - 2.1 8.2 8.2 1 9.3 1.9 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.11 KZN85942.1 - 4.1e-48 163.8 29.4 4.1e-48 163.8 20.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN85942.1 - 9.2e-11 40.9 14.6 9.2e-11 40.9 10.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 KZN85942.1 - 0.0024 16.0 9.4 0.35 8.8 0.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Cytochrom_B558a PF05038.8 KZN85942.1 - 0.043 13.4 0.1 2 7.9 0.0 2.5 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit TPMT PF05724.6 KZN85943.1 - 1.3e-25 90.1 0.0 3.4e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KZN85943.1 - 1.5e-05 25.5 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN85943.1 - 3.2e-05 23.9 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN85943.1 - 0.00013 22.2 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN85943.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN85943.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN85943.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KZN85943.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 KZN85943.1 - 0.11 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 KZN85943.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.14 KZN85944.1 - 3.8e-16 59.7 3.2 7.8e-16 58.7 0.3 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KZN85944.1 - 3.7e-07 29.7 0.3 8.2e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 Peptidase C65 Otubain Dapper PF15268.1 KZN85944.1 - 0.0074 15.1 10.6 0.0081 15.0 7.4 1.1 1 0 0 1 1 1 1 Dapper SICA_alpha PF12887.2 KZN85944.1 - 0.2 11.4 3.0 0.38 10.4 2.1 1.5 1 0 0 1 1 1 0 SICA extracellular alpha domain Cep57_MT_bd PF06657.8 KZN85944.1 - 0.24 11.3 4.4 0.67 9.9 3.0 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3275 PF11679.3 KZN85944.1 - 2.2 7.8 12.7 2.2 7.8 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) adh_short_C2 PF13561.1 KZN85945.1 - 3.6e-26 92.4 0.0 4.4e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN85945.1 - 4.5e-26 91.7 0.0 6.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN85945.1 - 1.8e-07 30.9 0.0 3.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Trehalase PF01204.13 KZN85946.1 - 1.5e-189 630.9 0.0 1.8e-189 630.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KZN85946.1 - 5.2e-17 60.8 0.8 8.4e-17 60.1 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 KZN85946.1 - 0.14 12.0 0.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix domain ICL PF00463.16 KZN85947.1 - 3.6e-286 949.4 3.2 4.1e-286 949.2 2.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KZN85947.1 - 2.1e-12 46.7 0.1 5.5e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 KZN85947.1 - 0.067 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Pre-toxin TG NTF2 PF02136.15 KZN85948.1 - 3e-12 46.9 0.0 4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 KZN85948.1 - 0.0052 16.9 0.0 0.0069 16.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KZN85948.1 - 0.019 15.3 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Choline_kinase PF01633.15 KZN85949.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KZN85949.1 - 0.0014 18.4 1.8 0.0071 16.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 KZN85949.1 - 0.028 14.2 0.0 4 7.2 0.0 2.4 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) WaaY PF06176.6 KZN85949.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF4629 PF15442.1 KZN85949.1 - 6.8 6.8 10.4 2.3 8.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Aldedh PF00171.17 KZN85950.1 - 2.8e-77 260.0 0.0 3.8e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF281 PF03436.8 KZN85950.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Adap_comp_sub PF00928.16 KZN85951.1 - 1.9e-52 177.9 0.0 2.4e-51 174.3 0.0 2.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KZN85951.1 - 0.0001 22.0 0.1 0.00017 21.3 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NST1 PF13945.1 KZN85951.1 - 0.0038 17.3 4.5 0.0059 16.6 3.1 1.2 1 0 0 1 1 1 1 Salt tolerance down-regulator Rubella_Capsid PF05750.6 KZN85951.1 - 0.025 14.0 8.0 0.044 13.1 5.5 1.3 1 0 0 1 1 1 0 Rubella capsid protein BLVR PF06375.6 KZN85951.1 - 0.1 12.4 4.8 0.19 11.5 3.4 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SPT6_acidic PF14632.1 KZN85951.1 - 2.5 8.3 6.6 4.3 7.5 4.6 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2413 PF10310.4 KZN85951.1 - 3 6.5 6.0 3.9 6.1 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Ndc1_Nup PF09531.5 KZN85951.1 - 5.9 5.1 6.9 8.1 4.7 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4536 PF15055.1 KZN85952.1 - 0.00012 22.0 0.3 0.00051 20.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF4588 PF15251.1 KZN85953.1 - 0.097 12.6 14.5 2.9 7.8 10.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) SNF2_N PF00176.18 KZN85954.1 - 3.4e-84 282.1 0.2 5e-84 281.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KZN85954.1 - 1e-42 144.5 3.3 1.7e-42 143.8 1.1 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KZN85954.1 - 1.7e-36 125.0 1.6 1.7e-36 125.0 1.1 3.1 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 KZN85954.1 - 1.7e-14 53.4 0.0 7.4e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN85954.1 - 2.2e-09 37.4 0.0 1.3e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN85954.1 - 4.3e-06 26.3 0.0 9.8e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KZN85954.1 - 0.01 15.2 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 KZN85954.1 - 0.02 15.0 0.3 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KZN85954.1 - 0.03 14.2 1.0 0.079 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain Asp PF00026.18 KZN85955.1 - 1.7e-66 224.6 2.5 2e-66 224.4 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KZN85955.1 - 1.6e-07 31.4 0.0 2e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KZN85955.1 - 0.00077 19.9 1.8 0.27 11.7 0.3 3.0 2 1 0 2 2 2 2 Aspartyl protease ADH_zinc_N PF00107.21 KZN85956.1 - 3.5e-23 81.5 1.2 6.5e-23 80.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN85956.1 - 2.4e-20 72.3 1.0 3e-20 71.9 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN85956.1 - 0.00017 22.5 0.0 0.00038 21.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IlvN PF07991.7 KZN85956.1 - 0.0058 16.0 0.1 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 KZN85956.1 - 0.042 13.6 0.5 0.11 12.2 0.3 1.8 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.14 KZN85956.1 - 0.087 11.9 0.8 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN85956.1 - 0.098 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SpoU_methylase PF00588.14 KZN85957.1 - 9.4e-25 87.1 0.1 2.1e-23 82.7 0.1 2.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KZN85957.1 - 1.1e-05 25.4 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 KZN85958.1 - 1.1e-61 207.2 10.1 2.6e-61 205.9 7.0 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KZN85958.1 - 5.5e-56 189.5 0.0 8.3e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN85958.1 - 3.6e-15 55.5 0.0 1.3e-14 53.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KZN85958.1 - 4.7e-14 51.8 2.6 1.4e-13 50.3 1.8 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 KZN85958.1 - 2.6e-05 23.8 17.8 0.0019 17.8 3.6 3.6 3 1 1 4 4 4 2 PHD-finger Chromo PF00385.19 KZN85958.1 - 2.7e-05 23.7 3.9 0.047 13.3 0.2 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 KZN85958.1 - 0.0026 17.6 0.1 0.02 14.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KZN85958.1 - 0.026 14.6 0.1 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PHD_2 PF13831.1 KZN85958.1 - 0.13 11.6 14.0 0.15 11.4 5.0 3.4 2 1 1 3 3 3 0 PHD-finger MRP-S28 PF10213.4 KZN85961.1 - 3.6e-43 146.6 0.1 6e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 KZN85962.1 - 2.6e-22 79.2 0.1 4.7e-22 78.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Actin PF00022.14 KZN85963.1 - 4.2e-132 440.2 0.0 4.8e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3602 PF12223.3 KZN85964.1 - 1.5e-18 66.9 12.4 8.6e-13 48.4 1.0 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-U1 PF06220.7 KZN85967.1 - 4.1e-16 58.2 2.1 5.8e-16 57.7 1.4 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.7 KZN85968.1 - 4.1e-158 526.5 19.9 4.1e-158 526.5 13.8 1.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KZN85968.1 - 1.2e-38 132.3 0.0 1.9e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KZN85968.1 - 0.022 14.1 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DUF843 PF05814.6 KZN85968.1 - 0.094 12.5 5.2 5.4 6.8 0.1 3.3 2 1 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DEAD PF00270.24 KZN85969.1 - 4.4e-44 149.9 0.1 8.6e-44 149.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN85969.1 - 1.7e-21 75.8 0.0 4.4e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KZN85969.1 - 2.6e-20 71.7 0.1 4.9e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) GAGE PF05831.6 KZN85969.1 - 0.37 10.9 6.9 0.73 9.9 4.8 1.5 1 0 0 1 1 1 0 GAGE protein Flavin_Reduct PF01613.13 KZN85971.1 - 1.2e-25 90.1 0.0 1.6e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain UbiD PF01977.11 KZN85972.1 - 6e-133 443.2 0.0 1.1e-132 442.3 0.0 1.4 2 0 0 2 2 2 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase F-box PF00646.28 KZN85973.1 - 0.0012 18.4 0.3 0.0064 16.1 0.2 2.3 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 KZN85975.1 - 6.4e-16 58.0 2.4 1.3e-15 56.9 0.5 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain TPR_12 PF13424.1 KZN85975.1 - 0.12 12.3 0.3 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Flavoprotein PF02441.14 KZN85976.1 - 6.8e-31 106.6 0.4 8.7e-31 106.2 0.3 1.1 1 0 0 1 1 1 1 Flavoprotein HAD_2 PF13419.1 KZN85978.1 - 6.3e-14 52.5 0.0 2.8e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN85978.1 - 4.5e-12 46.8 0.0 2.3e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN85978.1 - 1.2e-06 28.0 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KZN85978.1 - 4.9e-06 26.8 0.0 8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KZN85978.1 - 0.026 13.8 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-CCHC PF00098.18 KZN85979.1 - 0.081 12.8 0.1 0.081 12.8 0.1 5.2 6 0 0 6 6 6 0 Zinc knuckle Nop14 PF04147.7 KZN85979.1 - 5.4 4.8 7.6 7.4 4.3 5.2 1.2 1 0 0 1 1 1 0 Nop14-like family ORMDL PF04061.9 KZN85980.1 - 1.2e-60 202.9 3.6 1.4e-60 202.7 2.5 1.0 1 0 0 1 1 1 1 ORMDL family CH PF00307.26 KZN85982.1 - 2.7e-13 49.9 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 KZN85983.1 - 6.7e-14 52.2 1.6 6.7e-14 52.2 1.1 2.3 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pro_3_hydrox_C PF05373.6 KZN85983.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Piwi PF02171.12 KZN85984.1 - 7.3e-67 225.4 0.0 1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KZN85984.1 - 3.8e-15 55.3 0.0 1.9e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 KZN85984.1 - 8.8e-15 53.8 0.9 1.3e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) EMP24_GP25L PF01105.19 KZN85988.1 - 1.2e-41 142.4 0.0 1.3e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 KZN85989.1 - 5.7e-22 77.1 0.1 1.2e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 KZN85990.1 - 1.5e-60 199.0 25.2 1e-11 44.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KZN85990.1 - 5.1e-05 21.6 6.0 0.5 8.4 0.1 3.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KZN85990.1 - 0.0034 15.7 0.0 0.66 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF2683 PF10884.3 KZN85990.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) TPR_12 PF13424.1 KZN85991.1 - 7.4e-08 32.2 11.6 0.00018 21.3 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN85991.1 - 0.0026 17.2 11.0 0.014 14.9 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN85991.1 - 0.0073 15.9 5.2 0.55 9.9 0.1 4.1 4 0 0 4 4 4 1 TPR repeat Med25_SD1 PF11235.3 KZN85991.1 - 0.021 15.1 0.9 0.021 15.1 0.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 TPR_7 PF13176.1 KZN85991.1 - 1.3 9.0 3.7 4.5 7.3 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN85991.1 - 3.3 7.6 10.6 1.4 8.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN85991.1 - 6.4 6.9 25.8 1.6 8.8 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF159 PF02586.9 KZN85992.1 - 1.1e-55 188.4 0.0 2.1e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Spore_coat_CotO PF14153.1 KZN85992.1 - 4.9 6.5 9.0 6.5 6.1 4.2 2.0 2 0 0 2 2 2 0 Spore coat protein CotO Med1 PF10744.4 KZN85994.1 - 1.9e-97 326.5 0.0 2.9e-97 325.9 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.19 KZN85995.1 - 6e-58 196.0 0.0 7.4e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KZN85995.1 - 5.9e-20 70.6 0.0 1e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 KZN85996.1 - 7e-32 110.5 30.4 7e-32 110.5 21.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN85996.1 - 0.14 11.6 7.1 0.13 11.7 3.7 1.8 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 FPN1 PF06963.7 KZN85996.1 - 0.15 10.4 6.4 0.057 11.7 2.3 1.8 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Rab5ip PF07019.7 KZN85996.1 - 0.27 11.3 7.9 4.9 7.3 0.7 3.2 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Sugar_tr PF00083.19 KZN85999.1 - 1.3e-104 350.3 24.3 1.5e-104 350.1 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN85999.1 - 1.7e-19 69.7 29.6 4.8e-15 55.1 3.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 KZN85999.1 - 0.38 10.1 2.9 0.82 9.1 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) zf-CCHC PF00098.18 KZN86000.1 - 3.7e-61 200.3 108.0 1.2e-06 28.1 1.4 13.4 13 0 0 13 13 13 13 Zinc knuckle zf-CCHC_3 PF13917.1 KZN86000.1 - 3.5e-12 45.8 85.7 0.0064 16.2 0.0 12.9 3 2 7 10 10 10 9 Zinc knuckle zf-CCHC_4 PF14392.1 KZN86000.1 - 1.9e-10 40.2 91.6 0.045 13.4 0.1 13.1 13 0 0 13 13 13 10 Zinc knuckle CHASE PF03924.8 KZN86000.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.1 1 0 0 1 1 1 0 CHASE domain zf-CCHC_2 PF13696.1 KZN86000.1 - 0.03 13.8 0.1 0.03 13.8 0.1 8.8 8 2 2 10 10 10 0 Zinc knuckle zf-CCHC_6 PF15288.1 KZN86000.1 - 2.5 7.8 82.0 0.034 13.8 1.2 11.5 10 1 1 11 11 11 0 Zinc knuckle DUF846 PF05832.7 KZN86001.1 - 2e-47 160.4 9.0 2.4e-47 160.1 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 KZN86001.1 - 0.77 9.7 11.2 0.34 10.8 1.3 2.2 2 0 0 2 2 2 0 Tic20-like protein HpcH_HpaI PF03328.9 KZN86002.1 - 2.1e-37 128.1 0.0 7.8e-37 126.2 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KZN86002.1 - 3.3e-11 42.6 0.0 6.1e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.5 KZN86003.1 - 2.5e-16 59.4 9.7 2.5e-16 59.4 6.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KZN86003.1 - 2.5e-13 50.0 0.4 1.2e-12 47.8 0.1 2.4 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 KZN86003.1 - 1.3e-06 27.9 2.2 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 KZN86003.1 - 0.14 11.6 1.6 0.41 10.1 0.1 2.4 2 0 0 2 2 2 0 CUE domain SNARE_assoc PF09335.6 KZN86004.1 - 1.4e-10 41.4 6.2 1.4e-10 41.4 4.3 2.4 1 1 1 2 2 2 1 SNARE associated Golgi protein Rhomboid PF01694.17 KZN86004.1 - 6.4 6.7 14.0 0.8 9.7 6.4 1.9 2 1 0 2 2 2 0 Rhomboid family Amino_oxidase PF01593.19 KZN86005.1 - 5.9e-92 309.0 0.0 8.1e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KZN86005.1 - 4e-11 42.8 0.0 8.7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KZN86005.1 - 5.3e-07 29.5 0.1 1.2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KZN86005.1 - 8.1e-05 22.8 0.7 0.00018 21.6 0.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.19 KZN86005.1 - 0.0017 17.2 0.3 0.033 13.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN86005.1 - 0.0024 17.9 0.0 0.077 13.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.5 KZN86005.1 - 0.05 13.9 1.1 0.11 12.8 0.8 1.6 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.9 KZN86006.1 - 1.2e-27 97.1 0.1 1.5e-27 96.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN86006.1 - 1.5e-14 54.1 0.1 1.8e-12 47.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN86006.1 - 6.1e-09 36.2 0.1 6e-06 26.4 0.0 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KZN86006.1 - 9.4e-05 22.6 0.1 0.012 15.8 0.0 3.0 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KZN86006.1 - 0.00014 21.8 0.7 0.031 14.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN86006.1 - 0.00076 18.6 1.5 0.0028 16.8 0.1 2.2 2 1 1 3 3 3 1 Thi4 family DAO PF01266.19 KZN86006.1 - 0.0041 16.0 2.9 5 5.9 0.0 3.7 2 2 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KZN86006.1 - 0.0057 15.6 0.1 0.42 9.4 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KZN86006.1 - 0.041 12.9 0.8 7.9 5.4 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 KZN86006.1 - 0.071 11.9 5.7 4.3 6.0 0.1 3.8 3 2 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KZN86006.1 - 0.15 10.8 4.3 0.65 8.7 0.2 3.4 3 1 2 5 5 5 0 FAD binding domain PhoD PF09423.5 KZN86007.1 - 1.6e-06 26.9 0.0 6.8e-06 24.9 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 KZN86008.1 - 1.1e-52 178.9 1.2 1.6e-52 178.4 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KZN86008.1 - 7.6e-28 96.1 0.1 1.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 KZN86009.1 - 1.1e-18 67.0 0.2 2.4e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KZN86009.1 - 1.1e-16 60.8 5.9 6.3e-08 32.1 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KZN86009.1 - 0.02 14.4 4.1 0.3 10.5 2.8 2.2 1 1 0 1 1 1 0 BAR domain DUF724 PF05266.9 KZN86009.1 - 0.1 12.1 2.0 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 KZN86009.1 - 0.34 10.7 1.3 7.2 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.15 KZN86009.1 - 0.64 9.7 4.4 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 KZN86009.1 - 0.86 9.1 5.0 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 IncA protein ADIP PF11559.3 KZN86009.1 - 1.6 8.6 5.6 13 5.6 0.0 2.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FAD_binding_3 PF01494.14 KZN86010.1 - 3.8e-21 75.5 0.0 9.3e-18 64.3 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KZN86010.1 - 5.9e-06 25.3 0.0 1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 KZN86010.1 - 0.0042 16.0 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KZN86010.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.19 KZN86010.1 - 0.013 14.3 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN86010.1 - 0.049 13.4 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN86010.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KZN86010.1 - 0.066 11.6 0.1 0.095 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KZN86010.1 - 0.075 11.6 0.1 0.95 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_His PF13393.1 KZN86011.1 - 2.4e-36 125.3 0.0 2.9e-30 105.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KZN86011.1 - 7.3e-17 61.4 0.0 3.1e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KZN86011.1 - 7.6e-10 38.6 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KZN86011.1 - 0.006 15.4 0.1 0.098 11.4 0.1 2.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) UCH PF00443.24 KZN86012.1 - 1e-64 218.2 0.1 1.9e-64 217.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN86012.1 - 6.5e-33 114.4 1.2 7.8e-24 84.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KZN86012.1 - 0.0067 15.7 3.8 0.085 12.1 1.6 2.8 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.5 KZN86013.1 - 3.9e-32 110.1 0.6 4.3e-32 110.0 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 KZN86014.1 - 1.5e-43 149.4 13.3 1.8e-43 149.1 9.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 KZN86015.1 - 7.9e-34 117.1 0.1 7.4e-16 57.9 0.1 2.1 2 0 0 2 2 2 2 Dynamitin CCDC32 PF14989.1 KZN86015.1 - 0.011 15.6 1.7 0.073 12.9 0.5 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing 32 DUF4200 PF13863.1 KZN86015.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Spc24 PF08286.6 KZN86015.1 - 0.026 14.2 1.5 1.6 8.4 0.1 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spectrin PF00435.16 KZN86015.1 - 0.033 14.4 4.3 1.1 9.6 0.3 3.3 3 0 0 3 3 3 0 Spectrin repeat Laminin_II PF06009.7 KZN86015.1 - 0.043 13.5 3.1 0.066 12.9 0.1 2.8 2 1 1 3 3 3 0 Laminin Domain II Tropomyosin_1 PF12718.2 KZN86015.1 - 0.074 12.8 0.3 0.074 12.8 0.2 3.1 3 0 0 3 3 3 0 Tropomyosin like TBPIP PF07106.8 KZN86015.1 - 0.098 12.1 0.3 5.3 6.5 0.0 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3259 PF11652.3 KZN86015.1 - 0.11 12.6 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3259) Jnk-SapK_ap_N PF09744.4 KZN86015.1 - 0.12 12.4 3.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.15 KZN86015.1 - 0.16 11.7 6.7 0.38 10.5 0.6 2.7 3 0 0 3 3 3 0 Prefoldin subunit MbeD_MobD PF04899.7 KZN86015.1 - 0.28 11.1 3.7 1.5 8.7 0.3 3.2 3 0 0 3 3 3 0 MbeD/MobD like Syntaxin-6_N PF09177.6 KZN86015.1 - 0.44 10.9 5.9 2.7 8.4 0.4 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 KZN86015.1 - 0.61 9.6 6.8 1.9 8.0 0.1 3.5 3 1 0 3 3 3 0 Septum formation initiator IncA PF04156.9 KZN86015.1 - 1.1 8.8 5.5 3.1 7.3 0.3 2.5 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 KZN86015.1 - 1.5 7.7 4.2 2.4 7.1 0.2 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin PF02996.12 KZN86015.1 - 2.2 7.9 7.0 0.56 9.8 0.3 2.9 3 1 0 3 3 2 0 Prefoldin subunit GvpK PF05121.7 KZN86015.1 - 3 7.7 5.7 2.7 7.8 0.4 3.1 3 1 0 3 3 3 0 Gas vesicle protein K Hemerythrin PF01814.18 KZN86015.1 - 3.1 7.9 14.9 0.27 11.3 0.6 3.7 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain ADIP PF11559.3 KZN86015.1 - 3.6 7.4 8.2 15 5.4 0.4 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Aldedh PF00171.17 KZN86017.1 - 3.4e-134 447.6 0.5 4e-134 447.4 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 KZN86018.1 - 8e-165 547.8 16.5 1e-164 547.5 11.4 1.1 1 0 0 1 1 1 1 Calreticulin family DUF3227 PF11537.3 KZN86018.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Aldolase_II PF00596.16 KZN86019.1 - 3.9e-39 134.1 0.0 4.6e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 KZN86020.1 - 6e-88 294.0 4.9 9.3e-88 293.4 3.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KZN86020.1 - 1.9e-23 82.3 0.0 4.5e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KZN86020.1 - 0.014 14.6 0.9 0.38 9.9 0.7 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein cwf18 PF08315.7 KZN86021.1 - 0.03 14.7 0.4 0.043 14.2 0.3 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Flavin_Reduct PF01613.13 KZN86022.1 - 9.2e-29 100.2 0.1 1.5e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.1 KZN86022.1 - 0.0033 17.0 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) DUF1351 PF07083.6 KZN86023.1 - 1.4 8.5 15.9 0.69 9.5 9.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) V_ATPase_I PF01496.14 KZN86023.1 - 8.2 4.1 20.6 12 3.5 14.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NUDIX PF00293.23 KZN86024.1 - 8.6e-16 57.8 0.0 1.3e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain 4HBT_2 PF13279.1 KZN86025.1 - 6.7e-07 29.7 0.1 1.3e-06 28.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase-like superfamily Gluconate_2-dh3 PF13618.1 KZN86025.1 - 0.048 13.8 0.1 0.091 12.9 0.1 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF4080 PF13311.1 KZN86025.1 - 0.059 13.4 0.2 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Complex1_LYR_2 PF13233.1 KZN86026.1 - 3.7e-11 43.4 0.1 4.1e-11 43.2 0.1 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KZN86026.1 - 2.5e-06 27.1 0.6 3.4e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN86026.1 - 8.6e-06 25.8 0.3 1e-05 25.6 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_11 PF08241.7 KZN86027.1 - 3.4e-06 27.4 0.0 5.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN86027.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN86027.1 - 0.00037 20.2 0.0 0.00086 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN86027.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KZN86027.1 - 0.15 12.6 0.0 0.64 10.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 KZN86028.1 - 4e-19 69.5 0.2 7.7e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KZN86028.1 - 1e-14 53.7 9.9 1.1e-08 34.4 1.7 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN86028.1 - 3.2e-10 39.6 5.2 1.8e-08 33.9 4.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KZN86028.1 - 4.4e-07 29.0 5.7 0.015 15.2 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KZN86028.1 - 0.00039 20.1 9.2 0.36 11.2 0.2 4.8 4 0 0 4 4 4 2 Leucine rich repeat APH PF01636.18 KZN86029.1 - 4.1e-13 49.6 0.7 8.6e-13 48.5 0.5 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN86029.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mito_carr PF00153.22 KZN86030.1 - 2.1e-30 104.2 2.6 2.2e-13 49.7 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IId PF09221.5 KZN86030.1 - 8.6 6.3 7.2 14 5.7 0.9 3.1 2 1 1 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like FMN_red PF03358.10 KZN86032.1 - 4.6e-25 87.9 0.0 6.7e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KZN86032.1 - 0.038 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Abhydrolase_6 PF12697.2 KZN86033.1 - 9.1e-20 71.5 0.2 1.2e-19 71.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN86033.1 - 4.8e-17 61.5 0.0 1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KZN86033.1 - 9.2e-14 51.4 0.0 2.1e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN86033.1 - 0.0013 18.0 0.1 0.014 14.7 0.1 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 KZN86033.1 - 0.002 17.7 0.1 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KZN86033.1 - 0.026 13.4 0.0 0.046 12.5 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S10 PF00450.17 KZN86033.1 - 0.032 13.3 0.0 0.5 9.4 0.0 2.0 1 1 0 2 2 2 0 Serine carboxypeptidase PDZ_assoc PF10600.4 KZN86033.1 - 0.055 13.7 0.3 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors GCD14 PF08704.5 KZN86034.1 - 7.2e-09 35.5 0.0 0.00069 19.1 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 KZN86034.1 - 0.0038 17.7 0.0 5.6 7.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Metallophos PF00149.23 KZN86035.1 - 9.9e-10 38.1 0.9 2.7e-09 36.7 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN86035.1 - 7.5e-06 25.8 0.2 1.7e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.14 KZN86035.1 - 0.071 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase NAD_binding_1 PF00175.16 KZN86036.1 - 3.8e-07 30.6 0.0 0.037 14.6 0.0 2.8 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KZN86036.1 - 6.2e-06 26.1 0.0 8.7e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KZN86036.1 - 0.086 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain GATA PF00320.22 KZN86039.1 - 6.4e-16 57.4 5.4 1.2e-15 56.5 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 KZN86039.1 - 3e-09 37.2 0.0 1.3e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 KZN86039.1 - 1.4e-08 34.7 0.0 3.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KZN86039.1 - 2.8e-08 33.5 0.5 1.6e-07 31.0 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 KZN86039.1 - 5e-08 32.9 0.0 1.3e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 KZN86039.1 - 0.00092 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 KZN86039.1 - 0.0043 16.9 0.1 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain AAA_23 PF13476.1 KZN86040.1 - 2.7e-29 102.9 1.5 2.7e-29 102.9 1.0 7.9 2 1 2 4 4 4 1 AAA domain SMC_N PF02463.14 KZN86040.1 - 1.1e-16 60.7 5.4 1.4e-09 37.5 2.2 3.5 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KZN86040.1 - 1e-11 44.5 0.0 4.2e-11 42.6 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KZN86040.1 - 8.2e-08 32.5 12.4 0.0021 18.0 0.0 4.6 4 1 0 4 4 4 2 AAA domain AAA_13 PF13166.1 KZN86040.1 - 1.1e-07 30.7 139.6 0.00026 19.6 0.0 7.2 2 1 2 5 5 5 4 AAA domain AAA_29 PF13555.1 KZN86040.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KZN86040.1 - 0.0024 17.5 1.7 0.006 16.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KZN86040.1 - 0.036 13.1 0.0 0.0062 15.6 17.3 4.5 3 2 0 3 3 3 0 AAA ATPase domain DASH_Dam1 PF08653.5 KZN86040.1 - 0.71 9.6 4.2 50 3.7 0.3 4.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 L51_S25_CI-B8 PF05047.11 KZN86041.1 - 7.2e-21 73.6 0.0 1.4e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain tRNA-synt_1 PF00133.17 KZN86042.1 - 2.7e-38 131.3 0.0 2.7e-27 95.0 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KZN86042.1 - 5.1e-19 68.1 0.2 1.3e-11 43.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KZN86042.1 - 8.5e-16 58.0 0.0 3.1e-15 56.2 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KZN86042.1 - 3e-07 29.8 0.0 6.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KZN86042.1 - 0.0045 15.7 0.0 0.19 10.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (K) Aminotran_1_2 PF00155.16 KZN86043.1 - 6.3e-39 133.9 0.0 7.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KZN86043.1 - 1.9e-06 27.2 0.0 3e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 KZN86043.1 - 0.017 13.9 0.1 0.028 13.2 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-III MMR_HSR1 PF01926.18 KZN86044.1 - 1.6e-06 28.0 0.0 7.4e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.3 KZN86044.1 - 0.0005 20.5 0.1 0.00097 19.6 0.1 1.5 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase DUF258 PF03193.11 KZN86044.1 - 0.0087 15.2 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KZN86044.1 - 0.076 12.8 0.0 0.8 9.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 KZN86044.1 - 0.086 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Siah-Interact_N PF09032.6 KZN86044.1 - 0.38 10.8 2.8 0.25 11.4 0.3 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal Telomere_Sde2 PF13019.1 KZN86045.1 - 6.7e-64 214.4 0.9 1.1e-63 213.7 0.6 1.3 1 0 0 1 1 1 1 Telomere stability and silencing LacI PF00356.16 KZN86045.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Use1 PF09753.4 KZN86045.1 - 0.21 10.9 4.6 0.35 10.2 3.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 S10_plectin PF03501.10 KZN86046.1 - 9.4e-42 140.8 0.1 1.1e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Rio2_N PF09202.6 KZN86046.1 - 0.07 13.1 0.5 0.11 12.5 0.1 1.5 2 0 0 2 2 2 0 Rio2, N-terminal Peptidase_M20 PF01546.23 KZN86047.1 - 2.3e-22 79.4 0.2 3e-22 79.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN86047.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KZN86047.1 - 0.001 18.8 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 ATG2_CAD PF13329.1 KZN86050.1 - 1.2e-48 164.6 0.0 2.9e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KZN86050.1 - 4.7e-27 94.0 0.0 1.1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain A_deaminase PF00962.17 KZN86051.1 - 8.9e-41 139.8 0.0 1.6e-40 139.0 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase PIP5K PF01504.13 KZN86052.1 - 4.7e-27 94.6 0.0 6.4e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.11 KZN86053.1 - 1.1e-16 60.5 45.4 1.1e-16 60.5 31.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN86053.1 - 9.5e-08 30.6 17.3 3.5e-07 28.8 12.0 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nucleos_tra2_C PF07662.8 KZN86056.1 - 1.4e-68 230.5 0.2 1.4e-68 230.5 0.1 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KZN86056.1 - 2.8e-23 82.0 4.8 2.8e-23 82.0 3.3 3.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus SelP_N PF04592.9 KZN86056.1 - 4.3 6.6 6.0 6.3 6.1 4.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UQ_con PF00179.21 KZN86057.1 - 1.8e-46 157.0 0.0 2.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN86057.1 - 0.00062 19.6 0.0 0.00082 19.2 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KZN86057.1 - 0.00063 19.4 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KZN86057.1 - 0.00083 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase PF00069.20 KZN86058.1 - 5.8e-61 205.9 0.0 7.9e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86058.1 - 5.6e-24 84.6 0.0 7.6e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86058.1 - 1.4e-07 30.8 0.0 1.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN86058.1 - 0.00031 20.5 0.1 0.37 10.4 0.0 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN86058.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KZN86059.1 - 5.2e-05 22.8 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN86059.1 - 0.0006 19.3 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain DHBP_synthase PF00926.14 KZN86060.1 - 2.2e-72 242.3 0.0 1.4e-71 239.7 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 KZN86061.1 - 8.1e-07 28.9 0.2 4.2e-06 26.6 0.0 2.4 3 1 0 3 3 3 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.7 KZN86062.1 - 1.5e-31 108.8 24.7 1.5e-31 108.8 17.1 15.8 6 3 6 13 13 13 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KZN86062.1 - 0.00022 21.0 19.8 0.00022 21.0 13.7 15.6 6 2 12 18 18 18 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KZN86062.1 - 0.00041 18.9 12.8 0.00041 18.9 8.9 9.5 5 3 4 9 9 9 2 Weak chloroplast movement under blue light TMF_DNA_bd PF12329.3 KZN86062.1 - 0.0046 16.7 10.4 0.0046 16.7 7.2 21.9 16 5 8 25 25 25 5 TATA element modulatory factor 1 DNA binding Plasmid_stabil PF05016.9 KZN86062.1 - 0.081 13.3 0.1 0.081 13.3 0.1 5.5 5 0 0 5 5 5 0 Plasmid stabilisation system protein Scm3 PF10384.4 KZN86062.1 - 8.4 5.9 18.1 0.076 12.5 0.3 4.7 5 0 0 5 5 5 0 Centromere protein Scm3 Hexapep PF00132.19 KZN86063.1 - 3.3e-07 29.5 9.0 0.003 17.0 0.1 4.4 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Acid_PPase PF12689.2 KZN86064.1 - 7.9e-69 230.6 0.0 9.3e-69 230.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase AA_permease PF00324.16 KZN86066.1 - 5.1e-103 344.9 33.0 6.4e-103 344.6 22.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN86066.1 - 2.7e-26 92.0 37.7 3.4e-26 91.7 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KZN86067.1 - 2.6e-52 177.8 0.0 4.1e-39 134.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.20 KZN86068.1 - 4.7e-23 81.9 0.8 5.7e-22 78.4 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86068.1 - 2.6e-17 63.3 0.0 9.3e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86068.1 - 3.3e-11 43.1 0.4 2.2e-09 37.2 0.1 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 KZN86068.1 - 0.078 12.4 0.0 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Amidase PF01425.16 KZN86069.1 - 1.6e-78 264.5 1.1 4e-78 263.2 0.7 1.6 1 1 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.2 KZN86070.1 - 9.1e-18 64.9 0.0 1.4e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN86070.1 - 5.9e-17 61.9 0.0 5.2e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN86070.1 - 0.00018 21.2 0.0 0.0018 18.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KZN86070.1 - 0.0049 16.3 0.1 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KZN86070.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 KZN86071.1 - 1.3e-34 119.5 72.5 1.9e-30 105.7 35.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN86071.1 - 7.6e-06 24.7 35.1 0.0027 16.3 12.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Neurensin PF14927.1 KZN86071.1 - 2.6 7.4 10.3 11 5.4 0.0 3.6 3 1 0 3 3 3 0 Neurensin Ribonuc_L-PSP PF01042.16 KZN86072.1 - 3.1e-17 62.4 0.0 3.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.6 KZN86072.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NOGCT (NUC087) domain Fungal_trans PF04082.13 KZN86073.1 - 2.1e-30 105.4 0.2 3.5e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LRR_6 PF13516.1 KZN86074.1 - 0.0051 16.7 0.2 4.2 7.7 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat Sec63 PF02889.11 KZN86075.1 - 5.9e-55 186.7 0.3 8.5e-55 186.1 0.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KZN86075.1 - 1.5e-27 96.1 0.1 2.9e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KZN86075.1 - 4e-10 39.8 0.0 1.1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KZN86075.1 - 3.1e-09 36.5 0.0 8e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KZN86075.1 - 0.00046 20.3 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN86075.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain UvrD-helicase PF00580.16 KZN86075.1 - 0.025 13.9 0.0 0.025 13.9 0.0 2.3 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain T2SE PF00437.15 KZN86075.1 - 0.025 13.4 0.0 0.067 12.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.9 KZN86075.1 - 0.08 12.5 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.1 KZN86075.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 KZN86075.1 - 0.1 12.8 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Nuc_sug_transp PF04142.10 KZN86076.1 - 3.4e-68 229.3 0.6 4.8e-68 228.8 0.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KZN86076.1 - 8e-09 34.8 0.0 1.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KZN86076.1 - 2e-07 31.2 14.3 1.4e-06 28.4 1.7 2.5 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KZN86076.1 - 0.0014 18.7 6.7 0.0014 18.7 4.6 2.7 2 2 0 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 KZN86076.1 - 0.05 13.4 0.4 0.05 13.4 0.3 1.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 KZN86076.1 - 2.3 7.8 16.4 2 8.0 3.2 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family HORMA PF02301.13 KZN86078.1 - 1.7e-29 102.7 0.0 2.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KZN86078.1 - 0.0011 18.5 8.6 0.0024 17.5 6.0 1.5 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.27 KZN86079.1 - 8.4e-58 190.3 11.8 6.5e-09 35.3 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KZN86079.1 - 5.1e-09 35.7 0.2 9.8e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN86079.1 - 1.2e-07 31.1 0.0 3.1e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KZN86079.1 - 0.0093 14.1 11.0 0.57 8.2 0.1 4.9 3 3 2 5 5 5 3 Nucleoporin Nup120/160 MMR_HSR1 PF01926.18 KZN86080.1 - 1.2e-20 73.6 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KZN86080.1 - 2e-06 27.7 0.0 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 KZN86080.1 - 0.00016 20.9 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KZN86080.1 - 0.0002 20.5 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KZN86080.1 - 0.00045 19.7 0.0 0.0058 16.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KZN86080.1 - 0.0012 18.0 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KZN86080.1 - 0.0029 16.8 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KZN86080.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KZN86080.1 - 0.03 14.6 0.1 0.053 13.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KZN86080.1 - 0.088 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KZN86080.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein Clat_adaptor_s PF01217.15 KZN86081.1 - 3.3e-43 146.8 0.0 6.9e-43 145.7 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 KZN86082.1 - 3.8e-23 80.8 0.6 6.1e-23 80.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KZN86082.1 - 0.00034 20.4 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 CLASP_N PF12348.3 KZN86083.1 - 1.7e-06 27.5 0.0 2.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 KZN86083.1 - 6.1e-06 25.8 0.9 6.8 7.0 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat IncA PF04156.9 KZN86083.1 - 0.0017 17.9 1.9 0.0048 16.5 1.3 1.7 1 0 0 1 1 1 1 IncA protein Cnd1 PF12717.2 KZN86083.1 - 0.011 15.5 0.0 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 V_ATPase_I PF01496.14 KZN86083.1 - 0.024 12.4 1.2 0.037 11.8 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TAN PF11640.3 KZN86083.1 - 0.04 13.6 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair APG6 PF04111.7 KZN86083.1 - 0.27 10.2 15.2 0.096 11.7 8.1 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 KZN86083.1 - 0.33 10.8 12.8 1 9.2 8.9 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Hemagglutinin PF00509.13 KZN86083.1 - 0.61 8.1 1.9 0.92 7.5 1.3 1.1 1 0 0 1 1 1 0 Haemagglutinin COG5 PF10392.4 KZN86083.1 - 0.81 9.6 7.8 0.29 11.0 3.2 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.6 KZN86083.1 - 2.2 6.8 9.2 4 6.0 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KZN86083.1 - 3.5 7.5 15.7 26 4.6 8.2 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 KZN86083.1 - 4.7 7.2 7.7 0.94 9.4 0.6 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat CENP-Q PF13094.1 KZN86083.1 - 4.7 7.2 16.7 0.32 10.9 7.9 1.7 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 KZN86083.1 - 8.1 6.8 7.1 29 5.0 4.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) WD40 PF00400.27 KZN86084.1 - 1.3e-77 253.1 19.5 2.6e-12 46.1 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KZN86084.1 - 8.7e-11 40.6 1.5 0.0065 14.6 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KZN86084.1 - 0.18 10.0 0.1 5.8 5.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribosomal_S17 PF00366.15 KZN86085.1 - 0.0047 16.9 0.5 0.01 15.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 MGC-24 PF05283.6 KZN86085.1 - 1.3 8.8 5.5 1.9 8.2 3.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Glyco_transf_20 PF00982.16 KZN86086.1 - 5.9e-201 668.0 0.0 6.7e-201 667.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KZN86086.1 - 0.012 15.1 0.3 0.03 13.8 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Lactamase_B PF00753.22 KZN86087.1 - 2.9e-13 49.9 4.2 3.6e-13 49.6 2.9 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN86087.1 - 0.0093 15.5 1.5 0.02 14.4 1.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.15 KZN86088.1 - 3.9e-174 579.5 0.0 8e-174 578.4 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN86088.1 - 1.1e-45 154.9 0.0 2.3e-45 153.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 KZN86089.1 - 2e-09 37.3 4.9 3.3e-09 36.6 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KZN86089.1 - 0.00052 19.5 1.0 0.00094 18.6 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.2 KZN86089.1 - 0.00058 19.9 2.2 0.001 19.1 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KZN86089.1 - 0.013 15.5 0.4 0.021 14.9 0.3 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KZN86089.1 - 0.037 14.3 0.7 0.099 13.0 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN86089.1 - 0.083 13.2 1.0 0.18 12.1 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN86089.1 - 0.14 12.1 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN86089.1 - 0.86 10.0 0.1 0.86 10.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Mito_carr PF00153.22 KZN86090.1 - 8.5e-49 163.2 0.9 3e-20 71.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 KZN86092.1 - 2.8e-14 52.9 0.0 4.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86092.1 - 4.3e-09 35.8 0.0 9.3e-09 34.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN86092.1 - 1.3e-06 28.2 0.3 2.6e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN86092.1 - 4.2e-05 22.9 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KZN86092.1 - 0.00023 20.2 0.1 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KZN86092.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase CbiA PF01656.18 KZN86092.1 - 0.012 14.9 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SNF2_N PF00176.18 KZN86094.1 - 2.5e-64 216.9 0.0 3.4e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KZN86094.1 - 4.7e-59 199.4 3.4 2.8e-58 196.9 2.6 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 KZN86094.1 - 2e-12 46.7 0.0 4.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KZN86094.1 - 1.5e-05 24.0 0.0 5.7e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KZN86094.1 - 0.00062 19.6 0.0 0.0029 17.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.3 KZN86095.1 - 1.2e-82 275.4 7.0 1.2e-82 275.4 4.8 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KZN86095.1 - 3.7e-44 149.0 0.0 8.5e-42 141.4 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KZN86095.1 - 3.4e-09 36.8 1.7 0.0067 16.6 0.0 5.5 5 2 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KZN86095.1 - 3.8e-09 35.8 0.8 0.00021 21.0 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KZN86095.1 - 5.9e-09 36.1 2.1 0.003 17.9 0.0 5.5 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KZN86095.1 - 0.00022 21.1 1.9 0.47 10.2 0.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KZN86095.1 - 0.0037 17.0 0.2 14 5.6 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KZN86095.1 - 0.044 13.7 0.9 5.6 6.8 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) Ipi1_N PF12333.3 KZN86095.1 - 0.068 13.1 0.0 2.8 7.9 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.3 KZN86095.1 - 0.086 12.2 1.7 0.79 9.1 0.0 2.9 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal AMP-binding PF00501.23 KZN86097.1 - 0.014 13.7 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme TauD PF02668.11 KZN86098.1 - 5.2e-18 65.6 0.2 8e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KZN86098.1 - 6.4e-06 25.2 0.0 1.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 CsiD T2SI PF02501.12 KZN86098.1 - 0.26 11.2 0.9 30 4.6 0.0 2.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein I CP_ATPgrasp_2 PF14403.1 KZN86099.1 - 0.00075 18.2 0.0 0.0014 17.3 0.0 1.5 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 Glyco_hydro_15 PF00723.16 KZN86100.1 - 8.2e-105 350.9 0.1 9.4e-105 350.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Dehydrin PF00257.14 KZN86101.1 - 0.0054 17.0 14.1 0.01 16.1 9.8 1.5 1 1 0 1 1 1 1 Dehydrin DUF3602 PF12223.3 KZN86101.1 - 0.95 9.8 7.1 0.29 11.5 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) Ank_2 PF12796.2 KZN86102.1 - 1.7e-99 326.3 9.2 1.1e-14 54.4 0.0 11.6 7 3 6 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.25 KZN86102.1 - 1.1e-73 239.5 46.5 3.2e-07 29.8 0.4 22.4 24 1 0 24 24 24 13 Ankyrin repeat Ank_4 PF13637.1 KZN86102.1 - 1e-59 197.9 14.6 7.8e-08 32.6 0.0 13.7 10 3 5 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN86102.1 - 3.1e-52 169.3 27.7 0.0002 21.2 0.0 20.5 23 1 0 23 23 23 12 Ankyrin repeat Ank_5 PF13857.1 KZN86102.1 - 2.5e-47 157.8 21.1 1.5e-06 28.2 0.0 15.0 9 3 7 16 16 16 10 Ankyrin repeats (many copies) NACHT PF05729.7 KZN86102.1 - 3e-05 23.7 0.0 9e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN86102.1 - 4.6e-05 23.4 0.1 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KZN86102.1 - 0.0065 15.3 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KZN86102.1 - 0.011 15.8 0.2 0.071 13.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KZN86102.1 - 0.033 14.3 0.0 0.31 11.2 0.0 2.6 3 0 0 3 3 3 0 RNA helicase Ribonuclease_3 PF00636.21 KZN86103.1 - 1.9e-08 34.7 0.0 7e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN86103.1 - 6.8e-07 29.2 0.0 9.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Pkinase PF00069.20 KZN86104.1 - 1.9e-18 66.5 0.0 1.3e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86104.1 - 3.9e-06 26.1 0.2 5.5e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DNA_pol_B_thumb PF14791.1 KZN86104.1 - 0.0083 15.8 0.2 0.042 13.5 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase beta thumb Kdo PF06293.9 KZN86104.1 - 0.077 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.18 KZN86105.1 - 6e-35 120.9 11.7 8.4e-35 120.5 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KZN86105.1 - 6.6e-34 117.1 0.0 1.2e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KZN86105.1 - 2.5e-07 30.9 0.2 0.0016 18.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 KZN86105.1 - 7.4e-06 25.3 0.2 0.0014 17.8 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN86105.1 - 9.7e-05 22.4 0.1 0.0014 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KZN86105.1 - 0.00037 21.2 0.0 0.00087 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KZN86105.1 - 0.0012 18.7 0.0 0.034 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN86105.1 - 0.0013 18.8 0.0 0.0066 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KZN86105.1 - 0.0026 17.2 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KZN86105.1 - 0.0061 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KZN86105.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KZN86105.1 - 0.012 15.8 0.2 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KZN86105.1 - 0.014 14.8 0.2 0.06 12.7 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KZN86105.1 - 0.015 14.7 0.0 0.042 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 KZN86105.1 - 0.016 13.8 0.0 0.18 10.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 KZN86105.1 - 0.03 14.6 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KZN86105.1 - 0.031 14.2 0.0 0.14 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KZN86105.1 - 0.059 13.5 0.0 0.32 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KZN86105.1 - 0.077 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 KZN86105.1 - 0.18 11.7 1.8 1.1 9.2 0.3 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIM24 PF01987.12 KZN86106.1 - 2.1e-44 151.5 0.0 2.7e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PQQ_2 PF13360.1 KZN86106.1 - 0.00037 20.0 1.1 0.00067 19.1 0.6 1.5 1 1 0 1 1 1 1 PQQ-like domain DUF4402 PF14352.1 KZN86106.1 - 0.0076 16.7 0.1 0.019 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4402) DivIC PF04977.10 KZN86106.1 - 0.039 13.4 0.3 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Med9 PF07544.8 KZN86106.1 - 0.085 12.6 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 MFS_1 PF07690.11 KZN86107.1 - 5e-35 120.8 74.9 2.1e-25 89.1 27.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN86107.1 - 7.4e-06 24.8 41.1 0.00051 18.7 3.9 3.7 2 2 0 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 KZN86107.1 - 0.13 12.0 7.9 0.092 12.5 0.5 2.8 2 0 0 2 2 2 0 MFS_1 like family Amidase PF01425.16 KZN86108.1 - 2.9e-67 227.4 0.6 2.1e-65 221.3 0.0 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_88 PF07470.8 KZN86109.1 - 5.5e-56 190.0 7.4 7.1e-56 189.6 5.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pkinase PF00069.20 KZN86110.1 - 7e-14 51.5 0.0 1.2e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86110.1 - 1.6e-07 30.7 0.0 1.4e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN86110.1 - 0.0041 16.2 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN86111.1 - 6.8e-14 52.1 0.0 1.1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.11 KZN86111.1 - 0.00051 19.8 7.3 0.001 18.9 5.0 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF2180 PF09947.4 KZN86111.1 - 0.009 15.7 2.2 0.016 14.9 1.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) adh_short PF00106.20 KZN86112.1 - 3.8e-14 52.9 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86112.1 - 0.00041 20.1 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86112.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Phage_CI_repr PF07022.8 KZN86112.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Kinesin PF00225.18 KZN86113.1 - 4.1e-81 272.2 5.8 8.1e-81 271.3 1.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain HHH PF00633.18 KZN86113.1 - 4.9e-05 22.8 0.2 0.57 9.9 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 KZN86113.1 - 0.032 14.3 0.2 0.2 11.8 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain MerR-DNA-bind PF09278.6 KZN86113.1 - 0.97 9.8 6.5 1.6 9.1 2.1 3.1 3 0 0 3 3 3 0 MerR, DNA binding Sec23_trunk PF04811.10 KZN86114.1 - 3.3e-73 246.0 0.0 6.2e-73 245.1 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KZN86114.1 - 1.8e-24 85.1 0.3 4.5e-23 80.6 0.0 2.9 3 0 0 3 3 3 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KZN86114.1 - 7e-18 63.9 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KZN86114.1 - 6.2e-17 61.9 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KZN86114.1 - 3.5e-10 39.4 0.0 6.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 KZN86114.1 - 0.098 12.6 0.8 0.29 11.1 0.6 1.7 1 0 0 1 1 1 0 Testis-expressed 12 Pkinase PF00069.20 KZN86115.1 - 1.7e-75 253.5 0.0 2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86115.1 - 4.1e-32 111.2 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86115.1 - 0.0006 18.8 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN86115.1 - 0.001 18.1 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN86115.1 - 0.012 15.3 0.2 0.029 14.1 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN86115.1 - 0.07 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.10 KZN86116.1 - 2.1e-33 115.4 0.0 2.8e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TauD PF02668.11 KZN86116.1 - 0.065 12.8 0.1 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Aa_trans PF01490.13 KZN86117.1 - 3.2e-51 174.0 31.6 3.7e-51 173.8 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.3 KZN86118.1 - 1.1e-36 126.2 2.1 1.3e-36 126.0 1.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_3 PF07969.6 KZN86119.1 - 2.3e-57 195.0 0.1 2.6e-57 194.8 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KZN86119.1 - 6.8e-08 32.8 0.1 0.00043 20.3 0.0 3.3 2 2 1 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 KZN86119.1 - 9.6e-07 28.5 0.0 3.2e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN86119.1 - 1.3e-06 28.3 0.3 0.00013 21.7 0.2 2.7 1 1 0 1 1 1 1 Amidohydrolase family Linocin_M18 PF04454.7 KZN86119.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase NAD_binding_10 PF13460.1 KZN86120.1 - 5.4e-20 72.1 0.0 7.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN86120.1 - 3.9e-17 62.2 0.0 4.6e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KZN86120.1 - 3e-15 56.2 0.2 8.1e-15 54.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN86120.1 - 1.9e-11 43.2 0.1 3.9e-11 42.1 0.1 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN86120.1 - 3.1e-10 39.4 0.0 5.7e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KZN86120.1 - 1.3e-07 30.8 0.7 0.0007 18.5 0.1 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 KZN86120.1 - 0.00011 22.1 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KZN86120.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase DDE_Tnp_1_3 PF13612.1 KZN86120.1 - 0.0084 15.8 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 1 Transposase DDE domain KR PF08659.5 KZN86120.1 - 0.012 15.3 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 KR domain HIT PF01230.18 KZN86121.1 - 2.9e-17 63.0 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KZN86121.1 - 1e-09 38.6 0.0 1.4e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KZN86121.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 KZN86122.1 - 3.5e-43 146.8 0.0 6e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN86122.1 - 2.6e-16 59.4 0.1 9.9e-16 57.6 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KZN86122.1 - 2.5e-09 37.1 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 KZN86123.1 - 1.5e-29 101.4 1.6 2e-29 101.1 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 KZN86124.1 - 8.6e-52 175.8 1.3 1.1e-51 175.5 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN86124.1 - 2.8e-26 92.6 0.2 3.8e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KZN86124.1 - 0.0018 18.3 1.7 0.0018 18.3 1.2 3.4 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.1 KZN86124.1 - 0.04 13.2 4.5 0.77 8.9 0.0 3.6 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_S14 PF00253.16 KZN86125.1 - 4.5e-18 64.3 6.3 4.8e-18 64.2 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 KZN86125.1 - 0.11 12.2 0.3 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) LRV_FeS PF05484.6 KZN86125.1 - 0.31 10.6 3.7 0.48 10.0 2.6 1.3 1 1 0 1 1 1 0 LRV protein FeS4 cluster RNA_POL_M_15KD PF02150.11 KZN86125.1 - 0.58 9.9 2.5 7.4 6.3 0.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Prim_Zn_Ribbon PF08273.7 KZN86125.1 - 0.6 10.2 4.3 8.1 6.6 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Toxin_17 PF08086.6 KZN86125.1 - 0.93 9.6 5.0 0.55 10.3 0.3 2.0 1 1 1 2 2 2 0 Ergtoxin family Ytp1 PF10355.4 KZN86126.1 - 9.9e-112 372.5 8.3 9.9e-112 372.5 5.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KZN86126.1 - 6.1e-33 112.5 13.3 2.7e-31 107.2 3.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DUF4131 PF13567.1 KZN86126.1 - 2.2 7.6 6.1 3.5 7.0 1.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DLH PF01738.13 KZN86127.1 - 1.8e-31 109.1 0.0 2.1e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KZN86127.1 - 0.00045 19.9 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN86127.1 - 0.032 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rhomboid PF01694.17 KZN86128.1 - 4.2e-15 56.0 10.6 4.2e-15 56.0 7.4 1.9 2 0 0 2 2 2 1 Rhomboid family 5TM-5TMR_LYT PF07694.7 KZN86128.1 - 0.013 14.8 1.2 0.013 14.8 0.9 1.8 2 1 0 2 2 2 0 5TMR of 5TMR-LYT Pectate_lyase_3 PF12708.2 KZN86128.1 - 0.04 14.0 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase superfamily protein Gaa1 PF04114.9 KZN86129.1 - 5e-102 342.1 4.8 7.5e-102 341.6 3.3 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Fun_ATP-synt_8 PF05933.8 KZN86129.1 - 2.7 8.0 8.1 1.3 9.1 3.7 2.0 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) LysM PF01476.15 KZN86130.1 - 0.00083 19.2 0.2 0.0038 17.0 0.0 2.0 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.14 KZN86130.1 - 0.0087 16.0 8.7 0.018 15.0 4.0 2.9 2 0 0 2 2 2 1 Chitin recognition protein PCI PF01399.22 KZN86131.1 - 1.3e-10 41.5 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain RicinB_lectin_2 PF14200.1 KZN86132.1 - 7.6e-20 71.2 0.7 1.9e-15 57.0 0.1 2.0 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KZN86132.1 - 1.7e-06 28.0 0.3 3.1e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ribosomal_L31e PF01198.14 KZN86133.1 - 8.9e-38 127.8 1.8 1.1e-37 127.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 KZN86133.1 - 0.0039 16.5 0.1 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel CN_hydrolase PF00795.17 KZN86134.1 - 5.1e-33 113.9 0.0 7.2e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_5 PF13854.1 KZN86134.1 - 0.11 12.4 0.0 0.53 10.3 0.0 2.1 3 0 0 3 3 3 0 Kelch motif APH PF01636.18 KZN86135.1 - 1.1e-10 41.6 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family COG2 PF06148.6 KZN86136.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CDC50 PF03381.10 KZN86139.1 - 6.3e-70 235.5 0.8 8.5e-70 235.0 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF202 PF02656.10 KZN86140.1 - 5 7.4 12.9 13 6.1 0.2 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF202) Ran_BP1 PF00638.13 KZN86142.1 - 9.9e-11 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 KZN86142.1 - 2.8e-05 24.4 1.5 2.8e-05 24.4 1.0 6.2 6 1 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Pectate_lyase_3 PF12708.2 KZN86143.1 - 5e-80 268.8 26.0 8.6e-62 209.1 9.5 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KZN86143.1 - 8.6e-08 31.5 2.9 0.0033 16.8 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Cyclase PF04199.8 KZN86144.1 - 1.8e-16 60.2 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase adh_short_C2 PF13561.1 KZN86145.1 - 5.1e-29 101.7 0.1 5.8e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN86145.1 - 1.4e-27 96.6 0.2 1.8e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86145.1 - 2e-12 47.1 0.1 2.9e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.7 KZN86145.1 - 0.024 14.4 0.1 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease Chorion_S16 PF05836.7 KZN86145.1 - 0.044 13.6 0.6 0.11 12.4 0.2 1.7 1 1 0 1 1 1 0 Chorion protein S16 adh_short_C2 PF13561.1 KZN86146.1 - 1.4e-25 90.5 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN86146.1 - 2.8e-24 85.9 0.0 3.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86146.1 - 7.1e-14 51.8 0.0 9.6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN86146.1 - 0.00025 20.5 0.0 0.00045 19.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN86146.1 - 0.013 14.1 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_5 PF08323.6 KZN86146.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Starch synthase catalytic domain ThiF PF00899.16 KZN86146.1 - 0.29 10.9 1.7 7.3 6.4 0.4 2.9 2 1 0 3 3 3 0 ThiF family ABC_tran PF00005.22 KZN86148.1 - 2.1e-43 147.9 0.0 1.6e-25 89.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN86148.1 - 4.5e-32 111.5 25.6 1.2e-17 64.2 10.1 3.5 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KZN86148.1 - 1.6e-12 47.1 4.7 2e-05 23.9 1.2 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN86148.1 - 6.4e-11 42.7 0.0 0.0055 16.7 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KZN86148.1 - 2.4e-07 30.9 0.1 0.025 14.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN86148.1 - 1.5e-06 27.6 2.0 0.0016 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KZN86148.1 - 1.8e-06 27.4 0.1 0.012 15.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KZN86148.1 - 7.6e-06 26.0 3.0 0.093 12.7 1.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KZN86148.1 - 8e-06 26.3 1.3 0.013 15.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KZN86148.1 - 0.00012 21.1 1.8 0.24 10.2 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 KZN86148.1 - 0.00029 20.5 0.6 0.94 9.1 0.0 2.9 3 0 0 3 3 2 2 NACHT domain FtsK_SpoIIIE PF01580.13 KZN86148.1 - 0.00056 19.4 0.3 0.19 11.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KZN86148.1 - 0.0009 19.7 0.0 0.46 10.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KZN86148.1 - 0.0018 17.7 0.2 0.36 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA-like domain DUF258 PF03193.11 KZN86148.1 - 0.0022 17.2 0.7 1.8 7.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 cobW PF02492.14 KZN86148.1 - 0.0054 16.1 1.3 0.22 10.9 0.1 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KZN86148.1 - 0.0065 16.3 1.8 0.018 14.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KZN86148.1 - 0.0075 17.0 0.0 0.99 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KZN86148.1 - 0.01 15.7 0.0 0.9 9.5 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KZN86148.1 - 0.02 14.7 0.5 5.8 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KZN86148.1 - 0.02 15.1 0.0 3.9 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KZN86148.1 - 0.023 14.2 0.1 13 5.2 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 KZN86148.1 - 0.031 14.1 0.0 5.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KZN86148.1 - 0.05 13.3 0.6 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KZN86148.1 - 0.059 12.9 3.4 11 5.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN86148.1 - 0.066 12.9 5.6 0.74 9.6 0.2 3.7 3 0 0 3 3 3 0 Part of AAA domain NTPase_1 PF03266.10 KZN86148.1 - 0.087 12.5 0.6 11 5.7 0.0 2.5 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 KZN86148.1 - 0.1 12.2 0.3 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 KZN86148.1 - 0.14 11.4 2.5 7.2 5.8 0.0 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein m04gp34like PF12216.3 KZN86148.1 - 0.14 11.4 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Immune evasion protein TrwB_AAD_bind PF10412.4 KZN86148.1 - 0.17 10.5 1.3 3.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 KZN86148.1 - 0.21 10.5 1.1 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KZN86148.1 - 0.21 10.6 0.2 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin KaiC PF06745.8 KZN86148.1 - 0.22 10.6 0.9 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.18 KZN86148.1 - 0.25 11.1 6.4 1.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Dynamin family AAA_13 PF13166.1 KZN86148.1 - 0.88 7.9 0.2 16 3.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain SCP2 PF02036.12 KZN86149.1 - 8e-26 90.3 0.6 1.3e-25 89.6 0.4 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KZN86149.1 - 2e-06 27.7 0.1 2.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal YebF PF13995.1 KZN86149.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 YebF-like protein F-box-like PF12937.2 KZN86150.1 - 0.024 14.3 0.3 0.074 12.7 0.2 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 KZN86150.1 - 0.034 13.7 1.4 0.055 13.1 0.3 1.8 2 0 0 2 2 2 0 F-box domain SNF2_N PF00176.18 KZN86151.1 - 1.3e-71 240.8 0.1 1.8e-71 240.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN86151.1 - 6.1e-13 48.4 0.0 1.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KZN86151.1 - 6.3e-08 32.5 6.0 1.3e-07 31.5 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN86151.1 - 7.9e-08 31.8 2.9 1.5e-07 30.9 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KZN86151.1 - 7.4e-06 25.9 1.4 5.9e-05 22.9 0.0 3.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN86151.1 - 9e-05 22.0 0.0 0.00025 20.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KZN86151.1 - 0.00021 20.8 5.3 0.00041 19.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN86151.1 - 0.00041 20.1 4.2 0.00084 19.1 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KZN86151.1 - 0.0019 18.0 5.1 0.004 17.0 3.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN86151.1 - 0.0061 16.2 1.5 0.014 15.0 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KZN86151.1 - 0.25 10.9 6.6 1.4 8.5 4.2 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KZN86151.1 - 0.44 10.3 6.5 2.2 8.1 4.9 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Ras PF00071.17 KZN86152.1 - 4.4e-49 165.9 0.0 5.4e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN86152.1 - 1.8e-14 54.2 0.0 3.5e-14 53.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KZN86152.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KZN86152.1 - 0.00051 20.1 0.1 0.0041 17.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KZN86152.1 - 0.00088 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KZN86152.1 - 0.014 14.1 1.6 0.93 8.1 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KZN86152.1 - 0.022 14.0 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KZN86152.1 - 0.056 13.5 0.1 0.21 11.7 0.1 1.8 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KZN86152.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KZN86152.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PDZ_2 PF13180.1 KZN86153.1 - 6.9e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KZN86153.1 - 4.4e-06 26.7 0.0 8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 KZN86153.1 - 4.5e-06 26.7 0.0 8.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Myotub-related PF06602.9 KZN86153.1 - 0.0033 16.2 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF3336 PF11815.3 KZN86153.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) RhoGEF PF00621.15 KZN86154.1 - 1.2e-21 77.3 0.0 4e-21 75.7 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 KZN86154.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 PH domain SBDS PF01172.13 KZN86155.1 - 3.2e-24 84.5 0.0 3.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 KZN86155.1 - 0.0011 18.7 0.0 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 Phage XkdN-like protein UDG PF03167.14 KZN86156.1 - 9.2e-20 70.6 0.2 2.7e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily ORC6 PF05460.8 KZN86156.1 - 4.5 6.2 12.0 6.2 5.8 8.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) 7TMR-DISM_7TM PF07695.6 KZN86157.1 - 0.22 11.1 3.4 0.28 10.8 2.3 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.7 KZN86158.1 - 3.5e-21 75.7 0.0 6.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KZN86158.1 - 1.1e-20 73.4 0.0 2.6e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KZN86158.1 - 2.3e-18 66.4 9.0 2.3e-18 66.4 6.3 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KZN86158.1 - 8.9e-06 25.7 0.0 2.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KZN86158.1 - 0.082 13.4 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Methyltransf_2 PF00891.13 KZN86160.1 - 7.2e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KZN86160.1 - 0.00017 21.3 0.2 0.00042 20.0 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain NinB PF05772.7 KZN86160.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NinB protein Bac_luciferase PF00296.15 KZN86161.1 - 5.3e-60 203.1 0.4 6.9e-60 202.7 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase NRDE-2 PF08424.5 KZN86162.1 - 3e-70 236.6 0.0 7.9e-68 228.7 0.0 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KZN86162.1 - 0.063 13.9 9.7 39 5.2 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat BP28CT PF08146.7 KZN86163.1 - 1.8e-41 141.4 1.7 6.8e-41 139.5 0.9 2.3 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KZN86163.1 - 1.4e-29 102.5 0.3 1.4e-29 102.5 0.2 6.0 8 0 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 KZN86163.1 - 2.2e-09 37.4 4.5 0.064 13.5 0.1 6.4 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.17 KZN86163.1 - 8.6e-05 22.2 2.1 1.1 9.5 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 KZN86163.1 - 0.0014 19.0 11.9 2.8 8.5 0.1 7.8 6 1 1 7 7 7 1 HEAT-like repeat CARD PF00619.16 KZN86163.1 - 0.03 14.1 0.2 0.03 14.1 0.1 2.4 3 0 0 3 3 3 0 Caspase recruitment domain SSF PF00474.12 KZN86164.1 - 6.6e-23 81.0 30.5 6.6e-23 81.0 21.2 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Glyco_hydro_18 PF00704.23 KZN86165.1 - 5.8e-96 321.9 7.6 6.7e-96 321.7 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KZN86165.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 EthD PF07110.6 KZN86166.1 - 3.2e-20 72.8 1.6 3.8e-20 72.6 1.1 1.1 1 0 0 1 1 1 1 EthD domain Bul1_N PF04425.7 KZN86167.1 - 8.6e-07 27.8 3.1 4.9e-05 22.0 0.5 3.0 1 1 1 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.24 KZN86167.1 - 8.9e-06 25.5 0.0 8.3e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 KZN86167.1 - 8e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus CPSF_A PF03178.10 KZN86168.1 - 2.2e-99 332.6 0.0 6.3e-98 327.8 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KZN86168.1 - 6.2e-66 222.5 0.0 9.3e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 KZN86168.1 - 0.091 12.3 0.0 15 5.2 0.0 3.0 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal ubiquitin PF00240.18 KZN86169.1 - 2.3e-17 62.1 0.1 3.8e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KZN86169.1 - 4.5e-09 35.8 1.8 6.1e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KZN86169.1 - 3.5e-08 33.0 0.0 5.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KZN86169.1 - 7.3e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KZN86169.1 - 9.2e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 KZN86169.1 - 0.00017 22.0 0.1 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 KZN86169.1 - 0.085 13.1 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain EMP70 PF02990.11 KZN86170.1 - 1.1e-156 522.3 2.4 5.5e-156 520.0 1.7 2.1 1 1 0 1 1 1 1 Endomembrane protein 70 DDDD PF10161.4 KZN86170.1 - 0.3 10.7 1.3 17 5.1 0.2 2.6 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Sulfatase PF00884.18 KZN86171.1 - 4.8e-59 200.0 0.2 6.9e-59 199.5 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KZN86171.1 - 4.8e-22 77.5 0.5 1.2e-21 76.2 0.3 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KZN86171.1 - 3.4e-08 33.2 0.9 4.6e-06 26.2 0.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KZN86171.1 - 0.0018 18.5 0.4 0.015 15.5 0.1 2.2 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KZN86171.1 - 0.0022 16.5 0.0 0.0028 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KZN86171.1 - 0.0055 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 KZN86171.1 - 0.012 15.0 0.0 0.044 13.1 0.0 1.9 2 0 0 2 2 2 0 Metalloenzyme superfamily CN_hydrolase PF00795.17 KZN86172.1 - 6.7e-22 77.7 0.0 1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lactamase_B_2 PF12706.2 KZN86174.1 - 1.1e-14 54.4 0.7 1.1e-13 51.2 0.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN86174.1 - 4.6e-11 42.7 0.1 7.7e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MCPVI PF02993.9 KZN86174.1 - 0.18 11.9 0.2 0.18 11.9 0.1 1.5 2 0 0 2 2 2 0 Minor capsid protein VI Pyridoxal_deC PF00282.14 KZN86175.1 - 3e-76 256.2 0.0 4.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.23 KZN86176.1 - 8.3e-47 159.5 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PALP PF00291.20 KZN86179.1 - 2.5e-37 128.7 0.7 3.3e-37 128.3 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBDS_C PF09377.5 KZN86180.1 - 8.5e-52 174.1 0.0 1.3e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KZN86180.1 - 1.4e-26 92.0 0.1 2.9e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Cohesin_HEAT PF12765.2 KZN86180.1 - 0.036 14.0 0.2 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Peptidase_S10 PF00450.17 KZN86181.1 - 3.5e-128 428.2 0.4 4.3e-128 428.0 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KZN86181.1 - 2.8e-10 40.3 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 KZN86181.1 - 0.0018 18.1 0.0 0.032 14.1 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family TPR_MLP1_2 PF07926.7 KZN86181.1 - 0.22 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribosomal_S13 PF00416.17 KZN86182.1 - 3.7e-42 143.0 1.7 4.5e-42 142.8 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF1822 PF08852.6 KZN86182.1 - 0.0051 15.6 0.0 0.0066 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) FbpA PF05833.6 KZN86182.1 - 0.0073 14.9 0.0 0.0073 14.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.3 KZN86182.1 - 0.026 14.7 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) HHH_6 PF14579.1 KZN86182.1 - 0.047 13.7 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif PP28 PF10252.4 KZN86182.1 - 0.14 12.1 0.3 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 peroxidase PF00141.18 KZN86184.1 - 5.7e-46 156.8 0.0 8.6e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Viral_env_E26 PF11050.3 KZN86185.1 - 0.0054 15.9 2.6 0.0066 15.6 1.5 1.3 1 1 0 1 1 1 1 Virus envelope protein E26 Rab5-bind PF09311.6 KZN86185.1 - 0.065 13.1 7.6 0.41 10.5 0.6 2.3 1 1 1 2 2 2 0 Rabaptin-like protein TEX13 PF15186.1 KZN86185.1 - 0.54 9.8 4.2 0.94 9.0 2.9 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family TMF_TATA_bd PF12325.3 KZN86185.1 - 1.5 8.5 10.5 0.9 9.2 1.1 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KZN86185.1 - 1.7 8.5 8.7 3.7 7.4 3.6 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KZN86185.1 - 3.6 7.1 6.2 3.1 7.3 3.4 1.3 1 1 0 1 1 1 0 IncA protein Iso_dh PF00180.15 KZN86186.1 - 1.3e-109 366.3 0.0 1.5e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TPR_11 PF13414.1 KZN86187.1 - 2.1e-08 33.6 11.6 3e-07 29.9 0.5 2.8 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KZN86187.1 - 2.7e-07 29.9 1.6 0.029 14.2 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86187.1 - 8.9e-05 21.9 3.7 1.5 8.5 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KZN86187.1 - 0.062 13.4 0.9 0.13 12.4 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KZN86187.1 - 0.063 13.4 0.2 2.1 8.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 KZN86187.1 - 0.077 12.8 0.5 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Glyco_hydro_10 PF00331.15 KZN86188.1 - 2.9e-67 226.9 0.1 3.3e-67 226.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KZN86188.1 - 1.2e-11 44.0 11.7 1.2e-11 44.0 8.1 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2841 PF11001.3 KZN86189.1 - 1.6e-40 137.8 0.7 1.6e-40 137.8 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) SSXT PF05030.7 KZN86190.1 - 3e-05 23.4 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 2 SSXT protein (N-terminal region) PDZ_1 PF12812.2 KZN86191.1 - 3.1e-52 174.3 0.0 2.7e-33 113.6 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KZN86191.1 - 5.4e-14 52.2 0.4 1.7e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KZN86191.1 - 7.7e-11 41.7 0.0 5.4e-05 22.9 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KZN86191.1 - 1.4e-05 25.1 0.0 0.0095 16.0 0.0 3.7 3 0 0 3 3 3 1 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KZN86191.1 - 0.011 15.5 0.2 0.66 9.7 0.1 3.2 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KZN86191.1 - 0.38 9.1 0.1 0.73 8.1 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 INCENP_ARK-bind PF03941.10 KZN86192.1 - 1.8e-18 66.1 1.3 5e-18 64.6 0.9 1.9 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region CAF-1_p150 PF11600.3 KZN86192.1 - 0.0047 16.3 49.5 0.0047 16.3 34.3 5.7 5 1 1 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal PP-binding PF00550.20 KZN86193.1 - 3.8e-07 30.2 0.1 7.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN86193.1 - 0.0084 17.0 0.0 0.019 15.9 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reticulon PF02453.12 KZN86194.1 - 2.1e-35 121.8 3.8 2.7e-35 121.4 2.7 1.1 1 0 0 1 1 1 1 Reticulon BRX_N PF13713.1 KZN86194.1 - 0.035 13.5 0.1 0.096 12.1 0.0 1.7 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain DNA_topoisoIV PF00521.15 KZN86196.1 - 2.5e-133 445.0 0.0 4.3e-133 444.2 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KZN86196.1 - 1.1e-32 112.5 0.2 3.1e-32 111.1 0.2 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KZN86196.1 - 3.4e-13 49.4 0.0 1.6e-12 47.2 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KZN86196.1 - 2e-11 43.5 0.0 7.4e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RabGAP-TBC PF00566.13 KZN86197.1 - 3.8e-48 163.8 0.0 2e-47 161.4 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF972 PF06156.8 KZN86197.1 - 0.14 12.5 0.2 0.14 12.5 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF3405 PF11885.3 KZN86198.1 - 9e-148 492.5 2.3 1e-147 492.3 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) adh_short PF00106.20 KZN86200.1 - 9.8e-29 100.4 8.2 1.3e-28 100.0 5.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86200.1 - 3.8e-23 82.4 3.5 4.6e-23 82.2 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86200.1 - 2.6e-12 46.7 5.5 4e-12 46.1 3.8 1.2 1 0 0 1 1 1 1 KR domain ACT PF01842.20 KZN86200.1 - 0.041 13.3 0.2 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 ACT domain DUF2493 PF10686.4 KZN86200.1 - 0.2 11.2 1.2 1.3 8.5 0.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2493) Glyco_hydro_92 PF07971.7 KZN86201.1 - 3.2e-177 590.1 0.2 4.1e-177 589.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Zn_clus PF00172.13 KZN86202.1 - 2.1e-08 33.9 12.1 3.2e-08 33.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YliH PF10799.3 KZN86202.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) MFS_1 PF07690.11 KZN86203.1 - 6.5e-25 87.5 35.6 6.5e-25 87.5 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_POL_M_15KD PF02150.11 KZN86204.1 - 0.00033 20.2 4.6 0.0038 16.8 3.2 2.3 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit GIY-YIG PF01541.19 KZN86204.1 - 0.074 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 GIY-YIG catalytic domain Med4 PF10018.4 KZN86205.1 - 6e-45 152.9 0.4 1e-44 152.1 0.3 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 KZN86205.1 - 0.062 13.1 0.4 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ead_Ea22 PF13935.1 KZN86205.1 - 0.13 12.6 1.5 0.46 10.8 1.0 2.1 1 1 0 1 1 1 0 Ead/Ea22-like protein LPP PF04728.8 KZN86205.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper SnoaL PF07366.7 KZN86206.1 - 5.7e-05 22.7 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KZN86206.1 - 0.0011 19.2 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain COesterase PF00135.23 KZN86207.1 - 4.2e-80 269.9 0.1 4.9e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN86207.1 - 3.4e-08 33.3 0.1 1.3e-07 31.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN86207.1 - 0.012 14.3 0.0 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Transposase_23 PF03017.9 KZN86207.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase Beta-lactamase PF00144.19 KZN86209.1 - 4.8e-49 167.1 0.3 6.5e-49 166.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KZN86209.1 - 1.6e-12 47.1 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) CFEM PF05730.6 KZN86210.1 - 6.5e-11 41.9 10.9 1.1e-10 41.1 7.6 1.4 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.22 KZN86211.1 - 3.5e-61 202.9 6.8 6.9e-21 73.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 KZN86213.1 - 6.5e-44 148.7 0.0 7.4e-44 148.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN86213.1 - 0.056 13.3 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain RTA1 PF04479.8 KZN86214.1 - 4e-45 154.0 3.2 5.7e-45 153.5 2.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 KZN86214.1 - 0.021 14.5 0.6 0.021 14.5 0.4 2.7 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Zn_clus PF00172.13 KZN86215.1 - 5.4e-10 39.0 10.0 9.3e-10 38.2 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN86215.1 - 0.0012 17.5 0.4 0.0018 16.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 KZN86216.1 - 2.9e-75 253.2 26.5 4.2e-40 137.8 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN86216.1 - 2e-69 232.1 0.0 1.1e-34 119.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN86216.1 - 1.8e-17 63.3 1.2 4.3e-05 22.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN86216.1 - 1.4e-15 57.9 0.0 4.5e-06 26.8 0.0 4.2 2 2 1 3 3 3 3 AAA domain ABC_ATPase PF09818.4 KZN86216.1 - 2.9e-13 49.2 4.2 0.0001 21.0 0.1 4.4 5 0 0 5 5 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KZN86216.1 - 3e-10 40.9 0.0 0.0013 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN86216.1 - 3.8e-10 40.0 3.2 0.00011 22.1 0.4 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KZN86216.1 - 5.8e-10 38.5 0.3 0.00018 20.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KZN86216.1 - 6e-09 36.5 0.0 0.00015 22.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KZN86216.1 - 3.8e-08 32.7 0.0 0.0049 16.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN86216.1 - 8.4e-08 32.4 0.2 0.015 15.4 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN86216.1 - 2.9e-07 30.8 0.0 0.0072 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KZN86216.1 - 9.2e-06 25.8 0.1 0.056 13.6 0.0 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN86216.1 - 1.5e-05 24.7 0.2 0.48 10.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KZN86216.1 - 1.9e-05 24.5 0.0 0.12 12.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KZN86216.1 - 4.8e-05 22.8 0.9 0.54 9.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KZN86216.1 - 6.1e-05 22.6 0.5 1.5 8.5 0.0 4.0 3 0 0 3 3 3 1 Part of AAA domain Rad17 PF03215.10 KZN86216.1 - 0.00037 19.3 0.0 0.085 11.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 KZN86216.1 - 0.00048 20.1 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KZN86216.1 - 0.00052 19.9 0.0 0.97 9.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 KZN86216.1 - 0.00063 19.3 0.5 2.9 7.4 0.0 3.6 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 KZN86216.1 - 0.00096 18.8 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KZN86216.1 - 0.0012 18.3 4.9 0.76 9.1 0.0 4.2 4 1 1 5 5 4 1 AAA-like domain SbcCD_C PF13558.1 KZN86216.1 - 0.0027 17.5 1.9 2.5 8.1 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Sigma54_activ_2 PF14532.1 KZN86216.1 - 0.003 17.6 0.0 0.19 11.7 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF87 PF01935.12 KZN86216.1 - 0.0038 17.0 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KZN86216.1 - 0.0039 17.1 0.0 3 7.8 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KZN86216.1 - 0.0068 15.2 0.1 2.2 7.0 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain RNA_helicase PF00910.17 KZN86216.1 - 0.0084 16.2 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 KZN86216.1 - 0.0086 15.6 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 KZN86216.1 - 0.011 14.7 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 KZN86216.1 - 0.012 15.1 0.1 5.3 6.4 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 KZN86216.1 - 0.016 14.3 0.3 6.5 5.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.7 KZN86216.1 - 0.024 14.2 0.1 10 5.7 0.0 3.2 3 0 0 3 3 3 0 NACHT domain KAP_NTPase PF07693.9 KZN86216.1 - 0.024 13.6 0.0 0.29 10.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.16 KZN86216.1 - 0.036 13.2 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 KZN86216.1 - 0.042 13.5 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 KZN86216.1 - 0.072 12.5 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Guanylate_kin PF00625.16 KZN86216.1 - 0.079 12.3 0.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase G-alpha PF00503.15 KZN86216.1 - 0.094 11.3 0.0 5.1 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 KZN86216.1 - 0.14 11.6 0.1 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KZN86216.1 - 0.17 11.2 3.2 4.7 6.5 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KZN86216.1 - 0.21 11.2 0.4 48 3.6 0.0 3.4 4 0 0 4 4 4 0 NTPase ADH_N PF08240.7 KZN86217.1 - 7.5e-05 22.4 0.8 0.00013 21.7 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_4 PF07993.7 KZN86218.1 - 3.1e-37 127.8 0.0 3.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KZN86218.1 - 2.7e-06 26.9 0.0 4.1e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN86218.1 - 0.00068 18.6 0.0 0.00096 18.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KZN86218.1 - 0.058 12.2 0.0 0.24 10.2 0.1 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 KZN86218.1 - 0.091 12.6 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Cation_efflux PF01545.16 KZN86219.1 - 3e-53 180.7 9.9 3e-53 180.7 6.9 3.2 3 0 0 3 3 3 2 Cation efflux family Glyco_trans_1_4 PF13692.1 KZN86220.1 - 6e-30 104.1 0.1 2.8e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KZN86220.1 - 0.0061 16.7 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KZN86220.1 - 0.028 14.6 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFIIIC_delta PF12657.2 KZN86221.1 - 1.2e-43 148.7 1.0 2e-43 148.1 0.7 1.3 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KZN86221.1 - 4.8e-33 113.0 1.9 1e-32 111.9 1.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Thiolase_N PF00108.18 KZN86222.1 - 1.3e-93 312.7 0.4 1.3e-93 312.7 0.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN86222.1 - 3.6e-38 129.7 1.3 3.6e-38 129.7 0.9 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KZN86222.1 - 5.7e-05 22.7 0.3 5.7e-05 22.7 0.2 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KZN86222.1 - 6.2 6.5 6.7 7.5 6.2 0.2 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 KZN86223.1 - 9.1e-52 174.2 0.0 1e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN86223.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KZN86223.1 - 0.041 13.7 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 KZN86224.1 - 4.3e-111 370.8 0.0 9.4e-111 369.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF972 PF06156.8 KZN86224.1 - 0.033 14.5 1.1 0.033 14.5 0.7 5.8 2 2 3 5 5 5 0 Protein of unknown function (DUF972) XkdW PF09636.5 KZN86224.1 - 1.1 9.1 6.0 9.1 6.2 0.2 3.1 2 0 0 2 2 2 0 XkdW protein Filament PF00038.16 KZN86224.1 - 2 7.8 57.3 2.8 7.3 21.6 4.1 2 1 1 3 3 3 0 Intermediate filament protein FlaC_arch PF05377.6 KZN86224.1 - 8.9 6.2 13.1 9.7 6.1 0.5 5.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) EF-hand_7 PF13499.1 KZN86225.1 - 2.7e-29 101.0 10.8 1.6e-13 50.5 0.7 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KZN86225.1 - 6.2e-26 87.6 11.5 4.9e-08 31.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KZN86225.1 - 3.9e-25 85.4 3.2 5.8e-06 25.7 0.0 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KZN86225.1 - 1e-17 62.5 11.9 8.9e-05 21.6 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KZN86225.1 - 1.2e-15 56.8 12.2 5.4e-06 25.9 1.2 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KZN86225.1 - 5.5e-09 35.7 5.8 0.0023 17.6 0.1 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KZN86225.1 - 0.00012 21.9 0.4 0.058 13.3 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 KZN86225.1 - 0.00085 18.9 1.7 0.58 9.8 0.0 3.7 4 0 0 4 4 4 1 EF hand DUF1679 PF07914.6 KZN86225.1 - 0.013 14.1 0.3 1.1 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SPARC_Ca_bdg PF10591.4 KZN86225.1 - 0.031 14.2 0.7 1.1 9.3 0.1 3.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 KZN86225.1 - 0.13 12.3 0.1 5.6 7.0 0.0 2.9 3 1 1 4 4 4 0 EF hand EMP70 PF02990.11 KZN86226.1 - 1e-187 624.7 0.0 1.5e-187 624.1 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.10 KZN86227.1 - 1.5e-16 60.3 0.2 3.7e-16 59.0 0.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2775 PF10950.3 KZN86227.1 - 0.044 13.9 1.8 0.15 12.3 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) TT_ORF2 PF02957.10 KZN86227.1 - 0.35 11.5 6.1 0.42 11.3 0.5 2.6 2 0 0 2 2 2 0 TT viral ORF2 DUF2165 PF09933.4 KZN86228.1 - 0.02 14.5 0.3 0.052 13.2 0.1 1.6 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) FMO-like PF00743.14 KZN86229.1 - 5.5e-12 44.6 0.0 1.1e-06 27.1 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN86229.1 - 1.4e-10 41.5 0.1 7.3e-07 29.4 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN86229.1 - 3.1e-06 27.2 0.0 0.004 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN86229.1 - 4.9e-06 26.4 0.5 3.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN86229.1 - 3.6e-05 23.6 0.2 0.011 15.4 0.1 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 KZN86229.1 - 0.00037 19.5 0.0 0.00062 18.7 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN86229.1 - 0.00047 19.8 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KZN86229.1 - 0.0014 18.9 0.7 0.53 10.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN86229.1 - 0.029 12.8 0.3 0.3 9.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KZN86229.1 - 0.052 12.3 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KZN86229.1 - 0.063 12.1 0.0 33 3.2 0.0 3.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KZN86229.1 - 0.16 10.7 0.2 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_4 PF01565.18 KZN86231.1 - 4.3e-14 52.1 0.0 6.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 5_nucleotid_C PF02872.13 KZN86232.1 - 4e-33 114.5 0.0 1.4e-32 112.8 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KZN86232.1 - 5e-08 32.5 0.7 7.8e-08 31.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PD40 PF07676.7 KZN86232.1 - 4.4 7.0 6.2 0.62 9.7 0.0 2.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat His_Phos_1 PF00300.17 KZN86233.1 - 1.5e-09 38.1 0.0 1.8e-05 24.9 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) FMN_dh PF01070.13 KZN86234.1 - 6.5e-107 357.4 0.0 7.5e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KZN86234.1 - 2.8e-05 23.2 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KZN86234.1 - 0.0013 17.6 0.3 0.012 14.5 0.2 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KZN86234.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 KZN86234.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KZN86234.1 - 0.14 11.3 0.0 8.9 5.4 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein Hydantoinase_B PF02538.9 KZN86235.1 - 8e-188 624.9 0.0 9.9e-188 624.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KZN86235.1 - 2.6e-94 315.5 0.1 5.5e-92 307.9 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KZN86235.1 - 7.7e-57 191.6 0.0 6.8e-54 182.0 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.13 KZN86236.1 - 2.4e-21 75.7 0.2 4.6e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP_sub_h PF10775.4 KZN86236.1 - 0.16 11.7 0.3 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h Cyclase PF04199.8 KZN86237.1 - 2.7e-14 53.2 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Amidase_2 PF01510.20 KZN86237.1 - 0.019 14.9 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Chitin_synth_1 PF01644.12 KZN86238.1 - 1.4e-66 223.2 0.0 2.1e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KZN86238.1 - 1e-26 92.4 0.1 2.5e-26 91.1 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KZN86238.1 - 1.7e-22 79.5 0.0 4e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KZN86238.1 - 4.2e-09 36.5 0.0 1.4e-08 34.7 0.0 1.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KZN86238.1 - 5.4e-09 36.0 10.9 5.4e-09 36.0 7.6 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Muted PF14942.1 KZN86238.1 - 0.22 11.3 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein adh_short PF00106.20 KZN86239.1 - 3.4e-18 66.0 0.0 6.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86239.1 - 2.6e-05 23.9 0.0 0.0001 22.0 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN86239.1 - 2.7e-05 24.0 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN86239.1 - 0.00037 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 KZN86240.1 - 3.9e-37 127.7 43.4 3.9e-37 127.7 30.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 KZN86241.1 - 2.3e-41 141.2 0.1 2.8e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aminotran_1_2 PF00155.16 KZN86242.1 - 1.1e-65 221.9 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aa_trans PF01490.13 KZN86243.1 - 1e-47 162.5 39.9 1.2e-47 162.3 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aminotran_4 PF01063.14 KZN86245.1 - 8.5e-37 126.8 0.0 1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV BNR_2 PF13088.1 KZN86247.1 - 6.3e-30 104.3 2.8 2e-29 102.7 1.9 1.7 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KZN86247.1 - 1.2e-11 42.5 27.1 0.05 13.4 0.4 6.3 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.1 KZN86247.1 - 1.8e-10 40.4 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain Mo-co_dimer PF03404.11 KZN86247.1 - 0.46 10.1 5.4 24 4.5 0.0 4.2 3 1 1 4 4 4 0 Mo-co oxidoreductase dimerisation domain DHDPS PF00701.17 KZN86248.1 - 1.1e-41 142.3 0.0 1.4e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family NTPase_P4 PF11602.3 KZN86248.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Diphthamide_syn PF01866.12 KZN86248.1 - 0.13 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Fungal_trans_2 PF11951.3 KZN86249.1 - 1.1e-13 50.5 0.0 1.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86249.1 - 2.4e-07 30.5 10.7 4e-07 29.8 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KZN86250.1 - 4.2e-63 212.8 0.0 5.2e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KZN86251.1 - 5.8e-33 114.0 27.7 5.3e-32 110.8 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.1 KZN86251.1 - 0.17 11.3 1.8 1.6 8.1 0.1 3.0 2 1 1 3 3 3 0 PgaD-like protein Transferase PF02458.10 KZN86253.1 - 5.1e-10 38.3 0.0 5.8e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 Transferase family DAO PF01266.19 KZN86255.1 - 1.8e-46 158.7 0.0 3.3e-46 157.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN86255.1 - 1.2e-06 28.3 0.0 0.008 15.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KZN86255.1 - 1.3e-05 24.2 0.2 9.3e-05 21.4 0.0 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN86255.1 - 2.9e-05 23.1 0.1 0.12 11.2 0.0 2.4 2 1 1 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN86255.1 - 0.00015 21.7 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN86255.1 - 0.00039 20.5 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN86255.1 - 0.00081 19.3 0.0 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KZN86255.1 - 0.02 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3239 PF11580.3 KZN86255.1 - 0.083 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) ApbA PF02558.11 KZN86255.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KZN86255.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KZN86255.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 KZN86256.1 - 6.6e-53 179.8 0.0 5.4e-45 153.6 0.0 2.0 1 1 1 2 2 2 2 Streptococcal 67 kDa myosin-cross-reactive antigen like family Aa_trans PF01490.13 KZN86257.1 - 1.5e-77 260.7 24.6 1.8e-77 260.5 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Zn_clus PF00172.13 KZN86258.1 - 1.1e-06 28.4 9.0 1.6e-06 27.8 6.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN86258.1 - 7.8e-05 21.6 0.2 0.00027 19.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DEC-1_N PF04625.8 KZN86258.1 - 0.25 9.9 7.7 0.41 9.2 5.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pox_Ag35 PF03286.9 KZN86259.1 - 0.0005 19.6 2.9 0.00061 19.3 2.0 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF1168 PF06658.7 KZN86259.1 - 0.0042 16.6 4.3 0.0047 16.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) NST1 PF13945.1 KZN86259.1 - 0.11 12.5 6.9 0.16 12.0 4.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-C2H2_jaz PF12171.3 KZN86260.1 - 2.1e-37 126.3 9.3 0.00013 22.0 0.1 6.6 6 0 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN86260.1 - 4.1e-37 125.2 10.1 4.6e-05 23.4 0.1 6.4 6 0 0 6 6 6 6 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KZN86260.1 - 7.4e-18 63.5 14.6 0.2 12.0 0.1 6.6 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN86260.1 - 1.7e-16 59.4 21.3 0.086 13.2 0.1 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN86260.1 - 2.6e-14 52.5 15.7 0.5 10.3 0.1 6.9 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KZN86260.1 - 6.3e-14 51.9 9.2 2.4 8.3 0.0 7.1 2 1 5 7 7 7 6 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KZN86260.1 - 5.3e-07 29.1 19.2 3.6 7.3 0.0 6.3 6 0 0 6 6 6 6 zinc-finger of a C2HC-type C1_4 PF07975.7 KZN86260.1 - 8.6e-05 22.4 18.1 0.24 11.4 0.5 5.3 2 1 4 6 6 6 4 TFIIH C1-like domain zf-H2C2_2 PF13465.1 KZN86260.1 - 0.00033 20.8 14.2 43 4.6 0.0 7.2 7 0 0 7 7 6 0 Zinc-finger double domain LpxD PF04613.9 KZN86260.1 - 0.0016 17.9 0.0 50 3.5 0.0 4.8 1 1 4 5 5 5 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hint_2 PF13403.1 KZN86260.1 - 0.0074 16.2 0.0 1.2e+02 2.6 0.0 4.8 2 1 4 6 6 6 0 Hint domain Endonuclease_7 PF02945.10 KZN86260.1 - 0.009 15.7 8.7 29 4.4 0.0 5.8 2 1 3 5 5 5 0 Recombination endonuclease VII DUF629 PF04780.7 KZN86260.1 - 0.0094 14.5 9.8 7.6 4.9 0.2 5.3 1 1 5 6 6 6 1 Protein of unknown function (DUF629) SprT-like PF10263.4 KZN86260.1 - 0.024 14.2 5.1 16 5.1 3.5 3.4 1 1 0 1 1 1 0 SprT-like family Yippee-Mis18 PF03226.9 KZN86260.1 - 0.1 12.6 5.0 3.7 7.6 0.3 3.7 1 1 4 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1190 PF06693.6 KZN86260.1 - 0.54 10.2 8.9 26 4.8 0.1 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1190) C1_2 PF03107.11 KZN86260.1 - 1.3 9.1 16.2 14 5.9 0.2 6.2 6 0 0 6 6 6 0 C1 domain Zip PF02535.17 KZN86261.1 - 5.8e-51 173.3 1.5 6.8e-51 173.1 1.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF350 PF03994.9 KZN86261.1 - 0.81 9.4 7.5 3.1 7.6 0.1 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) Sugar_tr PF00083.19 KZN86262.1 - 2.4e-75 253.8 23.8 2.6e-75 253.7 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86262.1 - 8.9e-19 67.4 52.2 2.6e-14 52.7 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 KZN86263.1 - 2.2e-35 122.1 3.8 2.9e-35 121.7 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 KZN86264.1 - 3.4e-93 312.6 27.1 4e-93 312.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86264.1 - 4.1e-25 88.2 27.9 4.1e-25 88.2 19.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN86264.1 - 8.4e-06 24.2 2.7 8.4e-06 24.2 1.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KZN86264.1 - 0.0051 15.3 12.8 0.028 12.9 1.6 2.7 2 1 1 3 3 3 2 Reduced folate carrier 2OG-FeII_Oxy_3 PF13640.1 KZN86265.1 - 1.2e-11 44.9 0.0 2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KZN86265.1 - 4.4e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IQ PF00612.22 KZN86266.1 - 0.00085 18.7 1.8 0.0028 17.1 1.3 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif GFA PF04828.9 KZN86267.1 - 1.2e-14 54.0 0.1 1.2e-14 54.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 KZN86267.1 - 1.3 9.0 6.2 0.18 11.7 1.6 1.5 2 0 0 2 2 2 0 Cysteine-rich CWC Thiolase_C PF02803.13 KZN86268.1 - 9.4e-11 41.2 1.4 1.4e-09 37.4 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KZN86268.1 - 3.5e-07 29.7 0.0 2.7e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KZN86268.1 - 3.8e-07 29.3 0.0 2.7e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KZN86268.1 - 3e-05 23.6 0.5 7e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 KZN86268.1 - 0.0035 15.8 0.2 0.0075 14.7 0.0 1.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 KZN86268.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Acyl-CoA_dh_1 PF00441.19 KZN86269.1 - 3.8e-35 121.2 2.8 6.1e-35 120.5 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN86269.1 - 5.8e-24 84.8 0.1 1.3e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KZN86269.1 - 1.1e-15 56.8 0.0 2.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN86269.1 - 2.7e-13 50.3 0.1 6.2e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.15 KZN86269.1 - 0.0023 18.0 0.3 0.0077 16.3 0.0 1.9 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF3023 PF11224.3 KZN86269.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) CoA_transf_3 PF02515.12 KZN86270.1 - 2.4e-61 206.3 1.0 3.4e-55 186.2 0.1 2.2 2 0 0 2 2 2 2 CoA-transferase family III Lipase_GDSL_2 PF13472.1 KZN86271.1 - 4e-18 66.1 2.3 4.9e-18 65.8 1.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN86271.1 - 2.3e-14 53.8 0.3 2.8e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Amidase PF01425.16 KZN86272.1 - 2.2e-11 43.2 0.0 6.2e-05 22.0 0.0 2.5 2 1 1 3 3 3 2 Amidase Fungal_trans_2 PF11951.3 KZN86272.1 - 0.0012 17.5 1.1 0.0057 15.2 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Recep_L_domain PF01030.19 KZN86273.1 - 3.5e-05 23.7 0.1 0.036 14.0 0.1 3.1 1 1 1 2 2 2 1 Receptor L domain Ecm33 PF12454.3 KZN86273.1 - 0.00023 20.9 0.9 0.00023 20.9 0.6 2.9 3 0 0 3 3 3 1 GPI-anchored cell wall organization protein VSP PF03302.8 KZN86273.1 - 0.00089 17.9 0.6 0.00089 17.9 0.4 1.6 2 0 0 2 2 2 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.10 KZN86273.1 - 0.0019 17.6 0.1 0.0046 16.4 0.1 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 P12 PF12669.2 KZN86273.1 - 0.004 17.3 2.9 0.017 15.3 0.0 2.7 3 0 0 3 3 2 1 Virus attachment protein p12 family Rifin_STEVOR PF02009.11 KZN86273.1 - 0.0058 16.3 0.3 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Rifin/stevor family RCR PF12273.3 KZN86273.1 - 0.0091 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 KZN86273.1 - 0.03 12.5 0.0 0.043 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KZN86273.1 - 0.068 13.5 0.3 0.15 12.5 0.1 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 KZN86273.1 - 0.069 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SKG6 PF08693.5 KZN86273.1 - 0.075 12.3 8.4 0.2 10.9 5.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 KZN86273.1 - 0.11 12.2 0.1 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF1191 PF06697.7 KZN86273.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2550 PF10739.4 KZN86273.1 - 0.18 11.7 0.4 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) Lamp PF01299.12 KZN86273.1 - 0.18 10.9 2.7 0.11 11.6 0.6 1.6 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF4381 PF14316.1 KZN86273.1 - 0.19 11.8 0.2 0.36 10.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2207 PF09972.4 KZN86273.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2215 PF10225.4 KZN86273.1 - 0.22 10.9 0.9 0.43 9.9 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Aldo_ket_red PF00248.16 KZN86274.1 - 6.6e-33 113.7 0.0 8.4e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pro-kuma_activ PF09286.6 KZN86275.1 - 1.1e-45 155.2 0.1 2.2e-45 154.2 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KZN86275.1 - 5.9e-05 22.3 0.4 9.7e-05 21.6 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.19 KZN86276.1 - 5.3e-25 87.6 0.2 1.2e-24 86.4 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KZN86276.1 - 9.6e-24 83.2 0.0 1.9e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KZN86276.1 - 5.6e-22 78.0 0.0 1.2e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 KZN86276.1 - 1.2e-18 66.8 0.1 3.1e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KZN86276.1 - 4.9e-14 52.0 0.0 4.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KZN86276.1 - 2.7e-11 43.4 0.1 6e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 KZN86276.1 - 0.017 15.2 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 PAS fold Gemin7 PF11095.3 KZN86276.1 - 0.081 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DAO PF01266.19 KZN86277.1 - 2.3e-19 69.5 0.6 3.7e-18 65.5 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KZN86277.1 - 0.036 13.5 0.7 0.085 12.2 0.5 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KZN86277.1 - 0.057 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KZN86277.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 KZN86277.1 - 0.14 11.7 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF604 PF04646.7 KZN86277.1 - 0.18 10.9 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 OPT PF03169.10 KZN86278.1 - 3.9e-169 564.0 58.5 4.4e-169 563.8 40.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidohydro_1 PF01979.15 KZN86279.1 - 2e-33 116.4 0.0 2.9e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KZN86279.1 - 5.5e-08 32.4 0.1 3e-05 23.4 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KZN86279.1 - 1.8e-06 28.2 0.0 0.0091 16.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KZN86279.1 - 5.6e-05 22.8 0.0 0.00015 21.5 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KZN86279.1 - 0.00037 19.5 0.0 0.00059 18.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dpy-30 PF05186.8 KZN86279.1 - 0.035 13.5 0.1 0.095 12.2 0.1 1.7 1 0 0 1 1 1 0 Dpy-30 motif Fungal_trans PF04082.13 KZN86280.1 - 1.2e-22 80.0 0.0 2.7e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86280.1 - 9.2e-10 38.2 9.5 1.4e-09 37.7 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_25 PF01183.15 KZN86281.1 - 3.7e-41 140.9 0.2 4.3e-41 140.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 p450 PF00067.17 KZN86282.1 - 2.4e-36 125.2 0.0 3.1e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.1 KZN86283.1 - 7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN86283.1 - 3.1e-05 24.0 0.0 6.9e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN86283.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KZN86283.1 - 0.0043 16.8 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.14 KZN86284.1 - 1.2e-45 154.8 0.0 1.7e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN86284.1 - 1.2e-06 28.0 0.0 1.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN86284.1 - 0.0033 17.2 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.23 KZN86285.1 - 0.023 15.0 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 SET domain PEX11 PF05648.9 KZN86287.1 - 1.1e-35 122.8 0.1 1.3e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4345 PF14248.1 KZN86287.1 - 0.11 11.9 3.5 0.62 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) F-actin_cap_A PF01267.12 KZN86288.1 - 4.8e-90 301.2 0.0 5.4e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Fungal_trans_2 PF11951.3 KZN86290.1 - 3.9e-80 269.2 2.0 5.3e-80 268.8 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 KZN86290.1 - 6.2e-20 71.0 0.0 1.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KZN86290.1 - 0.037 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) tRNA-synt_2c PF01411.14 KZN86291.1 - 1e-09 37.2 0.0 1.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KZN86291.1 - 1e-06 28.4 0.3 2.1e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP2 PF01569.16 KZN86292.1 - 5.7e-24 84.2 1.3 5.7e-24 84.2 0.9 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF2933 PF11666.3 KZN86292.1 - 0.038 13.5 0.1 0.038 13.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2933) RseC_MucC PF04246.7 KZN86292.1 - 0.85 9.1 7.8 10 5.6 0.3 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF368 PF04018.8 KZN86292.1 - 1.2 8.3 5.5 0.25 10.5 1.6 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF368) MNHE PF01899.11 KZN86292.1 - 1.3 8.6 8.2 17 5.0 0.3 3.2 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit Med7 PF05983.6 KZN86293.1 - 1e-58 197.7 1.2 1.3e-58 197.4 0.8 1.1 1 0 0 1 1 1 1 MED7 protein GHMP_kinases_C PF08544.8 KZN86293.1 - 0.06 13.5 0.1 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal DUF4337 PF14235.1 KZN86293.1 - 8.5 6.1 7.6 6.5 6.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Fungal_trans PF04082.13 KZN86294.1 - 2.5e-15 56.0 0.1 4e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KZN86294.1 - 0.0041 15.7 2.1 0.02 13.5 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.17 KZN86295.1 - 3.2e-19 67.2 3.3 5.6e-05 22.8 0.1 9.5 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 KZN86295.1 - 3.9e-19 68.7 5.9 9.8e-06 25.7 0.0 7.3 7 1 1 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 KZN86295.1 - 2.2e-17 62.9 6.7 7.3e-05 23.1 0.0 9.5 9 2 2 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KZN86295.1 - 1.6e-10 41.2 0.2 0.22 11.9 0.0 6.2 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KZN86295.1 - 1e-09 38.1 1.1 1.5e-07 31.1 0.1 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 KZN86295.1 - 1.4e-08 34.7 3.7 0.02 14.7 0.0 4.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KZN86295.1 - 4.4e-07 29.4 0.0 0.0016 17.8 0.0 3.7 3 0 0 3 3 3 2 CLASP N terminal UME PF08064.8 KZN86295.1 - 8.3e-05 22.4 0.1 1.1 9.1 0.0 5.4 4 2 2 6 6 6 2 UME (NUC010) domain MMS19_C PF12460.3 KZN86295.1 - 0.00012 20.9 4.8 0.0022 16.8 0.0 3.6 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Arm PF00514.18 KZN86295.1 - 0.1 12.4 8.8 1 9.2 0.0 5.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Patched PF02460.13 KZN86296.1 - 2.6e-75 253.9 13.2 3.7e-74 250.0 9.1 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KZN86296.1 - 2.3e-48 163.5 7.3 2.3e-48 163.5 5.1 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KZN86296.1 - 0.00015 20.5 13.7 0.00015 20.5 9.5 3.5 3 2 0 3 3 3 1 MMPL family DUF4537 PF15057.1 KZN86297.1 - 0.0088 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) FlxA PF14282.1 KZN86297.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein TP2 PF01254.13 KZN86297.1 - 0.12 12.7 0.8 0.21 11.9 0.6 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 PAP1 PF08601.5 KZN86298.1 - 1.3e-77 261.8 27.8 1.3e-77 261.8 19.3 3.6 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KZN86298.1 - 7.2e-08 32.2 8.6 1.5e-07 31.2 6.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor MbeD_MobD PF04899.7 KZN86298.1 - 0.014 15.2 2.1 0.029 14.2 1.5 1.5 1 0 0 1 1 1 0 MbeD/MobD like Macoilin PF09726.4 KZN86298.1 - 0.016 13.5 11.5 0.1 10.8 2.4 2.1 2 0 0 2 2 2 0 Transmembrane protein bZIP_Maf PF03131.12 KZN86298.1 - 0.2 11.9 10.0 0.42 10.9 6.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 KZN86298.1 - 2.5 7.6 5.2 4.8 6.7 3.6 1.4 1 0 0 1 1 1 0 IncA protein DUF2433 PF10360.4 KZN86299.1 - 4.4e-51 172.6 0.0 6.8e-51 172.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KZN86299.1 - 0.0018 18.0 0.0 0.0046 16.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KZN86299.1 - 0.0054 16.1 0.0 0.0095 15.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1793 PF08760.6 KZN86300.1 - 6.4e-51 172.5 0.0 1.3e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KZN86300.1 - 0.02 14.0 0.1 0.051 12.7 0.1 1.8 1 1 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal GFO_IDH_MocA PF01408.17 KZN86301.1 - 1.5e-23 83.5 0.1 2.5e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN86301.1 - 1.6e-06 27.9 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.15 KZN86301.1 - 0.0081 16.0 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus TRAUB PF08164.7 KZN86302.1 - 5.6e-33 112.8 0.4 3.2e-32 110.4 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KZN86302.1 - 1.3e-31 109.4 1.8 1.3e-31 109.4 1.3 2.7 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.4 KZN86303.1 - 4.7e-33 112.9 0.1 1e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KZN86303.1 - 1.2e-16 60.6 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KZN86303.1 - 2.1e-09 37.5 0.0 8.3e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KZN86303.1 - 3.8e-05 22.9 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KZN86303.1 - 0.0022 17.0 1.8 0.0061 15.6 0.5 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 KZN86303.1 - 0.0073 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KZN86303.1 - 0.066 12.3 0.0 0.84 8.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Abhydrolase_3 PF07859.8 KZN86304.1 - 9e-41 139.7 0.1 3.3e-33 115.0 0.0 3.3 4 0 0 4 4 4 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN86304.1 - 9.1e-14 50.8 0.0 1.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KZN86304.1 - 0.00052 19.7 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KZN86304.1 - 0.0055 15.4 0.6 0.053 12.2 0.4 2.1 1 1 0 1 1 1 1 Carboxylesterase family adh_short PF00106.20 KZN86306.1 - 1.1e-16 61.2 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86306.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN86306.1 - 3.1e-08 33.6 0.0 4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN86306.1 - 0.00017 21.0 0.0 0.00095 18.6 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN86306.1 - 0.00019 21.5 0.5 0.0013 18.7 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KZN86306.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_3 PF13440.1 KZN86306.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidase PF01425.16 KZN86307.1 - 2.1e-32 112.5 1.1 3.6e-32 111.7 0.3 1.6 2 0 0 2 2 2 1 Amidase DAO PF01266.19 KZN86308.1 - 3e-32 111.9 0.0 4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN86308.1 - 2e-06 27.8 0.0 0.00084 19.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN86308.1 - 2e-06 27.9 0.1 0.081 12.9 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN86308.1 - 2.2e-06 27.9 0.0 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN86308.1 - 6.6e-06 26.0 0.1 1.7e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 KZN86308.1 - 0.0032 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KZN86308.1 - 0.0036 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KZN86308.1 - 0.0036 16.9 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KZN86308.1 - 0.0061 16.3 0.1 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 KZN86308.1 - 0.018 13.8 0.0 0.62 8.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 KZN86308.1 - 0.033 14.1 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 KZN86308.1 - 0.053 11.9 0.2 0.64 8.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KZN86308.1 - 0.065 12.0 0.0 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KZN86308.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain THF_DHG_CYH_C PF02882.14 KZN86308.1 - 0.17 10.9 0.2 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cerato-platanin PF07249.7 KZN86309.1 - 4.5e-48 162.1 1.1 5.3e-48 161.9 0.8 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 KZN86309.1 - 0.024 14.7 0.4 0.029 14.4 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Barwin PF00967.12 KZN86309.1 - 0.044 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Barwin family VP_N-CPKC PF11475.3 KZN86309.1 - 0.24 10.9 1.0 0.44 10.1 0.7 1.4 1 0 0 1 1 1 0 Virion protein N terminal domain Pyr_redox_2 PF07992.9 KZN86310.1 - 1.3e-08 34.9 0.0 5.7e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN86310.1 - 1.5e-07 31.6 0.0 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN86310.1 - 0.0003 20.7 0.0 0.00078 19.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN86310.1 - 0.0043 16.8 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KZN86310.1 - 0.024 13.0 0.0 0.038 12.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.1 KZN86310.1 - 0.053 13.7 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KZN86310.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KZN86310.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family YwiC PF14256.1 KZN86311.1 - 0.2 11.7 6.6 0.034 14.2 0.8 2.0 1 1 1 2 2 2 0 YwiC-like protein Lectin_C PF00059.16 KZN86312.1 - 0.036 14.6 0.1 0.087 13.4 0.1 1.6 1 0 0 1 1 1 0 Lectin C-type domain Sec62 PF03839.11 KZN86313.1 - 1.3e-57 194.7 0.3 1.3e-57 194.7 0.2 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 Pterin_4a PF01329.14 KZN86314.1 - 3e-23 81.4 0.3 3.5e-23 81.1 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.16 KZN86315.1 - 1.5e-08 34.4 6.2 2.2e-08 33.9 4.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN86315.1 - 7.5e-06 25.6 6.8 1.1e-05 25.1 4.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper WD40_alt PF14077.1 KZN86315.1 - 0.0022 17.5 0.2 0.9 9.2 0.0 2.4 1 1 1 2 2 2 2 Alternative WD40 repeat motif bZIP_Maf PF03131.12 KZN86315.1 - 0.018 15.3 5.1 0.025 14.8 3.5 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor GAS PF13851.1 KZN86315.1 - 0.031 13.4 1.4 0.037 13.2 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.7 KZN86315.1 - 0.039 12.9 2.1 0.053 12.5 1.4 1.1 1 0 0 1 1 1 0 CASP C terminal DUF4140 PF13600.1 KZN86315.1 - 0.042 14.2 3.5 0.056 13.8 2.1 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 KZN86315.1 - 0.052 13.0 1.3 0.11 12.0 0.9 1.5 2 0 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 KZN86315.1 - 0.21 11.8 0.4 0.21 11.8 0.3 1.8 1 1 1 2 2 2 0 Striatin family CAF-1_p150 PF11600.3 KZN86315.1 - 0.34 10.2 4.1 0.44 9.8 2.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zn_clus PF00172.13 KZN86316.1 - 2.4e-07 30.5 8.4 2.4e-07 30.5 5.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KZN86316.1 - 0.0046 17.1 2.1 0.018 15.3 1.5 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN86316.1 - 0.011 16.0 3.1 0.05 13.9 1.9 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_1 PF07690.11 KZN86317.1 - 6.4e-24 84.3 29.4 1.4e-23 83.2 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily priB_priC PF07445.7 KZN86318.1 - 0.0021 17.5 1.6 0.0021 17.5 1.1 1.5 2 0 0 2 2 2 1 Primosomal replication protein priB and priC DUF2046 PF09755.4 KZN86318.1 - 0.0079 15.1 3.1 0.0079 15.1 2.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.5 KZN86318.1 - 0.07 12.7 2.6 2.1 7.9 2.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2968 PF11180.3 KZN86318.1 - 1.9 7.8 15.0 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MerR-DNA-bind PF09278.6 KZN86318.1 - 2.9 8.3 8.1 2 8.9 0.1 2.3 2 0 0 2 2 2 0 MerR, DNA binding FlxA PF14282.1 KZN86318.1 - 7.9 6.4 18.6 29 4.6 10.0 2.7 2 0 0 2 2 2 0 FlxA-like protein Carn_acyltransf PF00755.15 KZN86320.1 - 4.8e-178 592.9 0.0 5.6e-178 592.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 KZN86321.1 - 1.4e-27 96.2 0.0 2.8e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KZN86321.1 - 0.0035 17.2 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 LCCL domain MIP PF00230.15 KZN86322.1 - 5.5e-23 81.6 4.2 9.1e-21 74.3 2.9 2.1 1 1 0 1 1 1 1 Major intrinsic protein DUF2953 PF11167.3 KZN86322.1 - 0.51 10.2 2.3 0.54 10.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) AAA_11 PF13086.1 KZN86323.1 - 1.4e-16 60.8 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KZN86323.1 - 4.3e-08 32.7 0.0 7.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KZN86323.1 - 0.032 13.7 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APH PF01636.18 KZN86325.1 - 5e-10 39.5 0.0 1.6e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DAO PF01266.19 KZN86326.1 - 1.8e-53 181.7 0.6 2.1e-53 181.5 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN86326.1 - 5.1e-05 23.4 0.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN86326.1 - 0.0019 17.9 1.9 0.12 12.0 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN86326.1 - 0.039 13.9 0.5 0.15 12.1 0.0 2.1 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4147 PF13660.1 KZN86326.1 - 0.056 12.5 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Thi4 PF01946.12 KZN86326.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KZN86326.1 - 0.14 10.9 6.0 3 6.6 4.2 2.2 1 1 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 KZN86326.1 - 0.18 10.7 0.1 0.62 8.9 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FA_desaturase PF00487.19 KZN86327.1 - 0.063 12.7 0.3 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase Hid1 PF12722.2 KZN86327.1 - 1.2 6.6 10.7 1.3 6.5 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HAD_2 PF13419.1 KZN86328.1 - 6.8e-28 98.0 0.1 8.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN86328.1 - 5.1e-05 23.7 0.0 0.0025 18.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN86328.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KZN86328.1 - 0.13 12.1 0.0 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AA_permease PF00324.16 KZN86329.1 - 9.2e-96 321.0 38.4 1.1e-95 320.7 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN86329.1 - 1.1e-26 93.4 40.0 1.3e-26 93.1 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF543 PF04418.7 KZN86329.1 - 0.33 10.9 5.2 6.3 6.8 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Fungal_trans PF04082.13 KZN86330.1 - 7.4e-21 74.1 0.8 1.4e-20 73.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86330.1 - 3.4e-07 30.0 8.5 8.6e-07 28.7 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.1 KZN86331.1 - 0.0012 18.8 0.2 0.008 16.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KZN86331.1 - 0.0094 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KZN86331.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KTI12 PF08433.5 KZN86331.1 - 0.22 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MatC_N PF07158.6 KZN86332.1 - 0.046 13.5 1.8 0.074 12.8 1.2 1.3 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus ATP_synt_I PF03899.10 KZN86332.1 - 0.61 10.2 7.9 1.4 9.1 5.0 1.9 1 1 1 2 2 2 0 ATP synthase I chain MFS_1 PF07690.11 KZN86333.1 - 9.1e-37 126.5 60.1 1.3e-26 93.1 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.12 KZN86334.1 - 3.8e-95 319.0 13.8 9.6e-94 314.4 9.6 2.3 1 1 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.8 KZN86334.1 - 5.3e-34 117.6 0.0 9.3e-24 84.1 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN86334.1 - 0.23 10.0 0.0 0.5 8.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Aminotran_3 PF00202.16 KZN86335.1 - 1.2e-97 326.8 0.0 1.5e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KZN86335.1 - 0.00019 20.4 0.0 0.00036 19.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.7 KZN86336.1 - 3e-16 59.3 3.8 5.5e-16 58.5 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) APH PF01636.18 KZN86337.1 - 1.1e-20 74.3 0.0 1.9e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2945 PF11160.3 KZN86338.1 - 7.1e-22 77.0 0.1 8.9e-22 76.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Hexokinase_2 PF03727.11 KZN86339.1 - 2.2e-76 256.2 0.0 2.9e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KZN86339.1 - 4.9e-55 186.0 0.0 6.4e-53 179.1 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Neugrin PF06413.6 KZN86340.1 - 4.8e-12 46.1 0.3 4.8e-12 46.1 0.2 1.8 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KZN86340.1 - 4.3e-05 23.5 9.6 0.00014 21.8 6.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 KZN86340.1 - 0.087 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 HTH domain YqhG PF11079.3 KZN86340.1 - 0.14 10.9 1.5 0.25 10.1 1.0 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Acyl-CoA_dh_N PF02771.11 KZN86340.1 - 0.29 11.7 4.7 0.37 11.3 0.2 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Rgp1 PF08737.5 KZN86341.1 - 3.3e-111 372.3 0.0 5.8e-111 371.5 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 KZN86341.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KZN86341.1 - 0.029 14.4 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.12 KZN86342.1 - 4.6e-71 238.0 0.1 6e-71 237.7 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 KZN86343.1 - 4.4e-41 140.5 2.9 5.2e-41 140.3 2.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 KZN86344.1 - 9.4e-06 23.7 4.0 0.00051 18.0 0.0 3.7 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase OrfB_IS605 PF01385.14 KZN86345.1 - 0.0053 16.1 0.4 0.0068 15.8 0.3 1.1 1 0 0 1 1 1 1 Probable transposase ADIP PF11559.3 KZN86345.1 - 0.011 15.5 6.0 0.013 15.3 4.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 KZN86345.1 - 0.021 14.7 4.1 0.025 14.4 2.8 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein UPF0449 PF15136.1 KZN86345.1 - 0.024 14.8 0.5 0.036 14.2 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF2076 PF09849.4 KZN86345.1 - 0.039 14.0 8.8 0.065 13.2 6.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4407 PF14362.1 KZN86345.1 - 0.12 11.2 6.0 0.13 11.2 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uds1 PF15456.1 KZN86345.1 - 0.12 12.3 5.3 0.21 11.5 3.6 1.5 1 1 0 1 1 1 0 Up-regulated During Septation DASH_Spc34 PF08657.5 KZN86345.1 - 0.15 11.6 5.8 0.42 10.2 4.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF4446 PF14584.1 KZN86345.1 - 0.2 11.4 1.3 0.29 10.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Atg14 PF10186.4 KZN86345.1 - 0.3 9.9 4.9 0.33 9.8 3.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KZN86345.1 - 0.35 10.3 2.9 0.57 9.7 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 KZN86345.1 - 0.92 9.9 7.5 0.7 10.3 4.3 1.6 1 1 0 1 1 1 0 SlyX Bromodomain PF00439.20 KZN86346.1 - 5.6e-17 61.4 0.0 1.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Diphthamide_syn PF01866.12 KZN86347.1 - 6.2e-114 380.3 0.0 8.3e-114 379.9 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 KZN86348.1 - 6.4e-42 143.8 0.2 1.2e-41 142.9 0.1 1.4 1 1 0 1 1 1 1 HMGL-like WD40 PF00400.27 KZN86349.1 - 3.2e-25 87.0 4.7 4.8e-06 26.2 0.0 9.0 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF742 PF05331.6 KZN86349.1 - 0.01 15.4 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF742) SPO22 PF08631.5 KZN86350.1 - 8.6e-22 77.5 0.0 5.5e-21 74.8 0.0 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 KZN86350.1 - 0.046 14.0 3.0 0.17 12.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86350.1 - 0.44 11.3 5.1 17 6.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SnoaL_2 PF12680.2 KZN86351.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain CENP-Q PF13094.1 KZN86352.1 - 1e-47 162.1 2.9 1.5e-47 161.6 2.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 KZN86352.1 - 0.25 11.7 1.8 1.7 9.0 0.9 2.4 2 0 0 2 2 2 0 SlyX HLH PF00010.21 KZN86353.1 - 4.6e-07 29.4 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.8 KZN86353.1 - 0.25 10.4 2.8 0.39 9.7 1.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cation_ATPase_C PF00689.16 KZN86354.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CtaG_Cox11 PF04442.9 KZN86355.1 - 3.5e-58 195.7 0.0 4.8e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rep_fac_C PF08542.6 KZN86356.1 - 1.5e-21 76.1 0.0 3.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KZN86356.1 - 3.4e-11 43.0 0.0 7.4e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KZN86356.1 - 2.1e-06 27.9 0.1 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN86356.1 - 2.5e-05 24.4 0.8 0.00024 21.2 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN86356.1 - 0.0013 18.7 2.9 0.094 12.6 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KZN86356.1 - 0.02 14.3 0.1 0.58 9.5 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 KZN86356.1 - 0.027 14.5 0.2 0.37 10.8 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain SNF2_N PF00176.18 KZN86356.1 - 0.03 13.1 0.1 0.036 12.8 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.1 KZN86356.1 - 0.035 13.9 0.1 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KZN86356.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Rad17 PF03215.10 KZN86356.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T4SS-DNA_transf PF02534.9 KZN86356.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Ribosomal_L16 PF00252.13 KZN86358.1 - 6.2e-29 100.4 0.2 7.9e-29 100.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KZN86359.1 - 2e-56 190.0 0.1 5.7e-56 188.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KZN86359.1 - 4.6e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KZN86359.1 - 7.6e-10 39.1 0.1 2.1e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN86359.1 - 1.6e-07 31.5 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN86359.1 - 2.2e-05 25.2 1.7 5.5e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 KZN86359.1 - 3.7e-05 22.6 0.0 8e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KZN86359.1 - 0.00075 19.1 0.1 0.0021 17.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KZN86359.1 - 0.0015 18.5 0.5 0.011 15.6 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KZN86359.1 - 0.0032 17.3 0.1 0.0092 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KZN86359.1 - 0.0051 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KZN86359.1 - 0.0088 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN86359.1 - 0.014 15.6 0.1 0.014 15.6 0.1 3.2 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 KZN86359.1 - 0.042 13.5 0.9 0.47 10.1 0.1 2.4 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.9 KZN86359.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KZN86359.1 - 0.086 12.4 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain SIN1 PF05422.7 KZN86360.1 - 2.6e-27 95.5 6.3 5.4e-17 61.5 3.5 2.4 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KZN86360.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG BRF1 PF07741.8 KZN86361.1 - 6.9 6.9 13.5 1.7 8.9 4.3 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Lectin_leg-like PF03388.8 KZN86362.1 - 3e-65 219.5 0.0 3.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KZN86362.1 - 0.1 11.9 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain zf-Tim10_DDP PF02953.10 KZN86363.1 - 9.5e-22 76.0 1.3 1.2e-21 75.7 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF3_subunit PF08597.5 KZN86363.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase PF00069.20 KZN86364.1 - 2.9e-67 226.5 0.0 3.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86364.1 - 4.4e-37 127.5 0.0 5.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86364.1 - 3.3e-06 26.2 0.0 6.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN86364.1 - 0.014 15.1 0.1 0.04 13.6 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family PRCC PF10253.4 KZN86365.1 - 4.6e-43 148.0 2.7 4.6e-43 148.0 1.9 2.7 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting AAA_5 PF07728.9 KZN86366.1 - 1e-129 427.0 0.2 4.7e-22 78.2 0.0 9.7 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KZN86366.1 - 4.3e-29 100.7 0.0 9e-11 41.4 0.0 7.2 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KZN86366.1 - 1.7e-28 99.4 0.0 0.00023 21.3 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN86366.1 - 2.8e-26 92.0 0.0 8.8e-05 22.4 0.0 7.5 6 1 0 6 6 6 5 AAA domain AAA_16 PF13191.1 KZN86366.1 - 8.2e-22 78.0 9.3 0.0006 19.8 0.5 8.4 7 0 0 7 7 6 4 AAA ATPase domain AAA_17 PF13207.1 KZN86366.1 - 1.6e-20 74.1 1.2 0.0029 18.3 0.0 7.5 7 0 0 7 7 6 3 AAA domain AAA_22 PF13401.1 KZN86366.1 - 2.1e-20 73.1 3.2 0.0053 16.9 0.0 8.2 7 1 0 7 7 7 4 AAA domain AAA_14 PF13173.1 KZN86366.1 - 3e-20 72.4 0.0 0.00044 20.1 0.0 7.7 7 1 0 8 8 6 3 AAA domain AAA_18 PF13238.1 KZN86366.1 - 1.2e-18 67.6 0.0 0.015 15.6 0.0 7.4 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.22 KZN86366.1 - 7.2e-16 58.7 0.7 0.0032 17.7 0.0 7.0 6 0 0 6 6 6 3 ABC transporter Zeta_toxin PF06414.7 KZN86366.1 - 1.2e-15 57.1 5.0 0.023 13.7 0.0 7.9 8 1 0 8 8 6 4 Zeta toxin UPF0079 PF02367.12 KZN86366.1 - 1.2e-13 50.7 4.8 0.079 12.5 0.0 6.6 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KZN86366.1 - 1.5e-13 50.5 0.0 0.0097 15.3 0.0 5.7 6 0 0 6 6 6 3 Sigma-54 interaction domain RNA_helicase PF00910.17 KZN86366.1 - 7.4e-13 48.6 0.9 0.76 9.9 0.0 6.7 6 0 0 6 6 6 3 RNA helicase Mg_chelatase PF01078.16 KZN86366.1 - 1e-12 47.6 0.4 1.8 7.6 0.0 8.8 9 0 0 9 9 9 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 KZN86366.1 - 2.8e-12 46.5 2.2 0.34 10.6 0.0 6.6 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 KZN86366.1 - 3.4e-12 46.6 0.1 0.015 15.3 0.0 5.8 5 0 0 5 5 5 2 Sigma-54 interaction domain SRP54 PF00448.17 KZN86366.1 - 6.8e-12 45.2 2.9 0.044 13.2 0.0 6.2 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KZN86366.1 - 1.8e-11 44.2 4.7 0.15 12.0 0.1 6.9 6 0 0 6 6 6 2 AAA domain Arch_ATPase PF01637.13 KZN86366.1 - 1.9e-11 44.1 1.6 1.1 8.8 0.0 6.5 7 0 0 7 7 6 2 Archaeal ATPase NACHT PF05729.7 KZN86366.1 - 2.4e-11 43.5 11.2 0.063 12.9 0.1 6.4 7 0 0 7 7 5 4 NACHT domain Miro PF08477.8 KZN86366.1 - 3.9e-11 43.5 0.8 2.4 8.6 0.0 6.8 6 0 0 6 6 6 1 Miro-like protein DUF258 PF03193.11 KZN86366.1 - 5.6e-11 41.8 2.2 0.075 12.2 0.0 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 KZN86366.1 - 6.2e-11 41.9 5.5 0.28 10.9 0.1 6.5 6 0 0 6 6 6 3 Part of AAA domain MMR_HSR1 PF01926.18 KZN86366.1 - 2.5e-10 40.3 0.1 0.0095 15.8 0.0 6.5 6 0 0 6 6 6 1 50S ribosome-binding GTPase AAA_25 PF13481.1 KZN86366.1 - 4e-10 39.4 2.0 0.91 8.8 0.0 6.4 7 0 0 7 7 5 1 AAA domain PduV-EutP PF10662.4 KZN86366.1 - 4.3e-10 39.2 2.9 0.1 12.0 0.0 6.2 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 KZN86366.1 - 1.4e-09 37.3 5.7 0.47 9.4 0.0 7.2 8 0 0 8 8 8 2 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KZN86366.1 - 1.9e-09 36.9 1.2 0.56 9.7 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain T2SE PF00437.15 KZN86366.1 - 4.5e-09 35.6 3.1 0.54 9.0 0.0 5.8 6 0 0 6 6 6 3 Type II/IV secretion system protein DUF815 PF05673.8 KZN86366.1 - 1.2e-08 34.1 0.9 0.52 9.1 0.0 5.6 6 0 0 6 6 6 3 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KZN86366.1 - 5.7e-07 29.1 0.1 2 7.7 0.0 5.4 5 0 0 5 5 5 2 IstB-like ATP binding protein NTPase_1 PF03266.10 KZN86366.1 - 6.5e-07 29.2 5.1 1.5 8.4 0.0 5.6 5 0 0 5 5 5 2 NTPase cobW PF02492.14 KZN86366.1 - 8.9e-07 28.5 5.5 2.4 7.5 0.0 6.4 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 KZN86366.1 - 1.4e-06 27.9 0.1 0.26 10.7 0.0 5.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.2 KZN86366.1 - 2.3e-06 26.9 0.4 0.22 10.5 0.0 4.8 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 ATP_bind_1 PF03029.12 KZN86366.1 - 5.7e-06 26.0 2.7 2.7 7.4 0.0 5.9 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 KZN86366.1 - 6e-06 26.0 0.0 0.59 9.7 0.0 3.9 3 0 0 3 3 3 1 Bacterial dnaA protein SRPRB PF09439.5 KZN86366.1 - 1.1e-05 24.7 3.7 1.9 7.6 0.0 6.1 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit PhoH PF02562.11 KZN86366.1 - 4.4e-05 22.8 0.2 1.2 8.3 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein AAA_24 PF13479.1 KZN86366.1 - 4.7e-05 23.0 0.0 10 5.6 0.0 5.0 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.10 KZN86366.1 - 0.00012 20.8 1.0 0.68 8.5 0.0 4.4 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KZN86366.1 - 0.00013 20.9 1.5 3.6 6.3 0.0 4.8 5 0 0 5 5 4 0 NB-ARC domain MCM PF00493.18 KZN86366.1 - 0.00018 20.4 0.5 2.5 6.8 0.0 4.5 5 0 0 5 5 5 1 MCM2/3/5 family TIP49 PF06068.8 KZN86366.1 - 0.001 17.9 3.7 0.65 8.6 0.0 4.6 5 0 0 5 5 5 1 TIP49 C-terminus KTI12 PF08433.5 KZN86366.1 - 0.0025 17.0 0.1 1.9 7.6 0.0 4.1 4 0 0 4 4 3 1 Chromatin associated protein KTI12 FeoB_N PF02421.13 KZN86366.1 - 0.0035 16.6 4.7 0.75 9.0 0.0 5.1 6 0 0 6 6 5 1 Ferrous iron transport protein B CbiA PF01656.18 KZN86366.1 - 0.0039 16.6 0.3 0.49 9.7 0.1 3.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 KZN86366.1 - 0.0048 16.0 0.4 23 4.0 0.0 4.4 5 0 0 5 5 4 0 KaiC ResIII PF04851.10 KZN86366.1 - 0.013 15.3 13.0 0.15 11.8 0.0 5.2 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 KZN86366.1 - 0.018 14.5 0.1 33 3.8 0.0 3.9 5 0 0 5 5 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 KZN86366.1 - 0.023 13.5 1.0 4.5 5.9 0.1 3.4 3 0 0 3 3 3 0 ArgK protein AAA_6 PF12774.2 KZN86366.1 - 0.047 13.2 0.0 35 3.8 0.0 4.4 6 0 0 6 6 2 0 Hydrolytic ATP binding site of dynein motor region D1 Septin PF00735.13 KZN86366.1 - 0.084 11.8 1.2 6.3 5.7 0.0 3.9 5 0 0 5 5 5 0 Septin AAA_15 PF13175.1 KZN86366.1 - 0.11 11.5 0.2 15 4.4 0.0 3.8 5 0 0 5 5 4 0 AAA ATPase domain Voltage_CLC PF00654.15 KZN86367.1 - 1.5e-90 303.7 21.9 1.5e-90 303.7 15.2 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KZN86367.1 - 7.3e-07 28.8 0.0 0.0023 17.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain CTK3 PF12243.3 KZN86368.1 - 1e-57 193.6 0.5 1.6e-57 193.0 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KZN86368.1 - 1.4e-18 66.6 10.2 3.8e-18 65.2 7.0 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KZN86368.1 - 0.0022 17.7 0.2 0.0038 17.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein U3_snoRNA_assoc PF08297.6 KZN86369.1 - 4.7e-15 55.5 1.0 4.7e-15 55.5 0.7 3.4 3 1 0 3 3 3 2 U3 snoRNA associated DUF155 PF02582.9 KZN86370.1 - 2e-53 180.9 0.7 3e-53 180.3 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF2205 PF10224.4 KZN86371.1 - 0.083 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF1180 PF06679.7 KZN86371.1 - 2 8.3 7.0 8.8 6.1 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Mito_carr PF00153.22 KZN86372.1 - 8e-48 160.1 4.1 1.8e-16 59.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3716 PF12511.3 KZN86373.1 - 1.2e-13 50.4 8.9 1.9e-13 49.8 6.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_clus PF00172.13 KZN86374.1 - 2.8e-08 33.5 7.2 5.2e-08 32.6 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN86374.1 - 5.1e-05 22.0 0.1 0.00013 20.7 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KZN86375.1 - 3.4e-51 169.3 19.8 5.1e-09 35.6 0.4 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KZN86375.1 - 4.4e-11 42.3 0.5 9e-11 41.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KZN86375.1 - 2.3e-09 35.9 8.3 0.002 16.3 0.2 5.0 1 1 4 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 KZN86375.1 - 0.00018 21.0 0.4 0.00047 19.7 0.3 1.8 1 0 0 1 1 1 1 F-box domain Lamp PF01299.12 KZN86375.1 - 0.033 13.3 1.8 0.066 12.3 1.2 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Zip PF02535.17 KZN86376.1 - 1.3e-39 136.0 10.6 1.7e-37 129.1 7.4 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3649 PF12365.3 KZN86376.1 - 4.1 7.0 9.6 1.4 8.5 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) RTA1 PF04479.8 KZN86377.1 - 1.3e-43 149.1 3.6 1.3e-43 149.1 2.5 1.3 2 0 0 2 2 2 1 RTA1 like protein SUR7 PF06687.7 KZN86377.1 - 0.19 11.2 9.3 15 5.1 6.5 2.8 1 1 0 1 1 1 0 SUR7/PalI family Alginate_lyase PF05426.7 KZN86378.1 - 1.7e-15 57.0 1.3 4.5e-15 55.7 0.9 1.7 1 0 0 1 1 1 1 Alginate lyase Zn_clus PF00172.13 KZN86378.1 - 0.0025 17.6 1.5 0.0044 16.8 1.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3554 PF12074.3 KZN86378.1 - 0.13 11.7 3.5 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) Hat1_N PF10394.4 KZN86379.1 - 3.9e-44 150.5 0.0 7.2e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Cas_Csy2 PF09614.5 KZN86379.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) SLX9 PF15341.1 KZN86379.1 - 0.71 10.3 3.5 1.4 9.3 2.4 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 LSM PF01423.17 KZN86380.1 - 2.6e-18 65.3 0.0 4.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN86380.1 - 0.0061 16.4 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RAM PF15320.1 KZN86380.1 - 0.69 10.2 6.5 0.97 9.7 4.5 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein API5 PF05918.6 KZN86380.1 - 4.6 5.6 12.7 6.2 5.1 8.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PPR_3 PF13812.1 KZN86381.1 - 3e-20 70.7 7.5 0.00049 20.1 0.0 8.8 8 1 1 9 9 9 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 KZN86381.1 - 2.9e-12 46.3 0.1 0.0027 17.6 0.0 7.9 5 3 4 9 9 9 4 PPR repeat family PPR PF01535.15 KZN86381.1 - 8.9e-07 28.4 6.4 3.9 7.6 0.1 7.3 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 KZN86381.1 - 0.12 11.9 0.0 28 4.3 0.0 4.5 6 0 0 6 6 6 0 PPR repeat DSPc PF00782.15 KZN86383.1 - 2.3e-10 40.1 0.0 4.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KZN86383.1 - 2.5e-06 27.0 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KZN86383.1 - 0.0095 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KZN86383.1 - 0.02 14.9 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate PTEN_C2 PF10409.4 KZN86383.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein CDKN3 PF05706.7 KZN86383.1 - 0.18 11.2 0.0 0.41 10.0 0.0 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PLA2_B PF01735.13 KZN86384.1 - 9.3e-27 93.3 0.0 3.9e-26 91.2 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 KZN86385.1 - 1.2e-73 248.0 0.0 2.3e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit NPV_P10 PF05531.7 KZN86385.1 - 0.08 13.2 2.8 4.6 7.5 0.0 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lyase_1 PF00206.15 KZN86386.1 - 2.8e-21 76.0 0.0 6.1e-21 74.9 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 KZN86386.1 - 2.2e-14 53.2 1.2 6.7e-14 51.6 0.0 2.4 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus DUF2189 PF09955.4 KZN86387.1 - 0.097 12.6 0.2 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) BCDHK_Adom3 PF10436.4 KZN86388.1 - 3.3e-70 234.8 0.0 4.5e-70 234.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KZN86388.1 - 1.7e-17 63.1 0.0 4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KZN86388.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 KZN86388.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family SKN1 PF03935.10 KZN86390.1 - 9.7e-220 729.9 0.1 1.1e-219 729.7 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AflR PF08493.5 KZN86391.1 - 0.036 13.1 2.1 0.044 12.8 1.4 1.4 1 1 0 1 1 1 0 Aflatoxin regulatory protein Ribosomal_L3 PF00297.17 KZN86392.1 - 1.3e-118 395.1 8.4 1.6e-118 394.8 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 KZN86393.1 - 9.1e-52 170.6 27.0 4.2e-08 32.4 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 KZN86393.1 - 1.9e-46 155.5 17.5 1.8e-10 40.3 0.3 6.5 3 2 1 6 6 6 6 TPR repeat TPR_2 PF07719.12 KZN86393.1 - 2.6e-46 151.8 17.5 6.6e-06 25.6 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86393.1 - 6.1e-39 128.8 20.3 1.5e-05 24.4 0.5 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86393.1 - 8.9e-31 105.6 19.4 2.7e-07 30.4 0.1 7.5 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86393.1 - 6.1e-30 103.2 12.4 3.7e-07 30.6 0.1 7.2 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KZN86393.1 - 4.5e-27 91.9 18.0 8.8e-05 22.4 0.1 10.0 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86393.1 - 1.2e-24 84.5 13.8 0.00042 20.6 0.0 10.0 4 2 7 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86393.1 - 2.4e-22 79.0 14.4 3.4e-05 24.0 0.0 7.5 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86393.1 - 1.1e-21 74.8 10.0 0.002 17.7 0.0 9.7 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KZN86393.1 - 9.8e-20 69.6 17.5 0.0049 17.2 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 KZN86393.1 - 1.7e-15 56.6 7.8 0.0062 16.3 0.0 7.3 3 2 5 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 KZN86393.1 - 2.6e-12 46.7 11.0 4.2e-08 33.1 0.8 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KZN86393.1 - 6.5e-09 35.2 8.4 0.00021 20.4 1.9 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.4 KZN86393.1 - 0.00097 18.6 5.3 0.71 9.2 0.0 3.4 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 KZN86393.1 - 0.00099 19.4 3.1 0.75 10.0 0.0 3.8 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_21 PF09976.4 KZN86393.1 - 0.0017 18.2 11.5 0.19 11.6 0.0 4.7 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 KZN86393.1 - 0.0024 17.9 0.2 2.2 8.4 0.1 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 KZN86393.1 - 0.093 12.6 17.7 0.87 9.5 0.5 5.8 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.4 KZN86393.1 - 0.13 12.1 0.6 3.5 7.4 0.1 2.8 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DnaJ-X PF14308.1 KZN86393.1 - 0.14 11.4 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing ChAPs PF09295.5 KZN86393.1 - 0.31 9.7 2.6 5.8 5.5 0.2 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) GFO_IDH_MocA PF01408.17 KZN86395.1 - 1.9e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN86395.1 - 4.9e-17 61.7 0.2 1.1e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.11 KZN86396.1 - 3.2e-35 121.5 28.4 3.2e-35 121.5 19.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN86396.1 - 0.075 12.8 0.2 0.075 12.8 0.2 3.0 3 0 0 3 3 3 0 MFS_1 like family RNase_T PF00929.19 KZN86397.1 - 9.7e-14 51.9 0.0 1.7e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-C2H2_jaz PF12171.3 KZN86397.1 - 0.0091 16.1 1.2 5.1 7.3 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DNA_pol_A_exo1 PF01612.15 KZN86397.1 - 0.01 15.3 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease zf-C2H2_2 PF12756.2 KZN86397.1 - 0.022 14.8 0.1 0.086 12.9 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KZN86397.1 - 0.033 14.3 0.9 8.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN86397.1 - 0.13 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KZN86397.1 - 0.14 12.5 0.0 31 5.2 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.17 KZN86398.1 - 1.1e-66 225.3 0.0 1.2e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 KZN86400.1 - 5.6e-35 120.6 0.4 6.8e-35 120.4 0.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Chromo PF00385.19 KZN86401.1 - 1.6e-08 34.1 0.0 3.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Fructosamin_kin PF03881.9 KZN86402.1 - 7.4e-42 143.2 0.0 9.6e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KZN86402.1 - 3.1e-07 30.3 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.16 KZN86403.1 - 1.5e-09 37.3 0.3 3.3e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ala_racemase_N PF01168.15 KZN86404.1 - 8.2e-26 90.9 0.1 1e-25 90.6 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 KZN86404.1 - 8.9e-20 70.6 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain SDH_alpha PF03313.10 KZN86404.1 - 0.014 14.4 0.4 1.5 7.7 0.2 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain GTP_CH_N PF12471.3 KZN86404.1 - 0.071 12.7 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal 2OG-FeII_Oxy_2 PF13532.1 KZN86405.1 - 4.8e-17 62.4 0.0 6.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KZN86405.1 - 2.7e-09 37.1 0.0 5.9e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KZN86405.1 - 0.033 14.6 0.1 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 KZN86406.1 - 1.8e-22 79.0 13.4 1.1e-08 34.8 0.0 6.2 4 2 2 7 7 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KZN86406.1 - 3e-17 62.3 0.0 5.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 KZN86406.1 - 7.3e-16 57.5 1.3 0.006 16.4 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN86406.1 - 3e-08 32.9 12.8 1.3 9.0 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN86406.1 - 1.2e-07 31.2 0.2 1.8e-05 24.2 0.0 5.2 3 2 1 6 6 5 3 TPR repeat TPR_1 PF00515.23 KZN86406.1 - 1.7e-06 27.3 2.7 0.76 9.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86406.1 - 4.3e-05 22.9 2.6 4.1 7.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86406.1 - 4.6e-05 23.6 3.7 0.69 10.7 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86406.1 - 6.4e-05 23.2 0.8 1.8 8.9 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 KZN86406.1 - 0.00011 22.2 0.0 0.00053 20.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN86406.1 - 0.00012 22.2 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KZN86406.1 - 0.00058 19.4 9.7 2.2 8.2 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86406.1 - 0.0016 19.0 4.1 9 7.1 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KZN86406.1 - 0.02 15.0 0.1 2.4 8.5 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN86406.1 - 0.022 15.1 0.0 6.2 7.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KZN86406.1 - 0.12 12.3 0.2 1.1 9.3 0.0 2.7 3 0 0 3 3 2 0 PPR repeat TPR_6 PF13174.1 KZN86406.1 - 0.29 11.6 2.9 41 4.9 0.0 4.6 7 0 0 7 7 3 0 Tetratricopeptide repeat Pilin_PilA PF14245.1 KZN86407.1 - 0.043 14.3 1.3 0.081 13.4 0.9 1.5 1 0 0 1 1 1 0 Type IV pilin PilA Podoplanin PF05808.6 KZN86408.1 - 0.0003 20.3 0.2 0.00053 19.5 0.1 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 KZN86408.1 - 0.004 15.8 0.5 0.0052 15.4 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Glycophorin_A PF01102.13 KZN86408.1 - 0.026 14.2 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A RdRP_5 PF07925.6 KZN86408.1 - 1 6.6 3.7 1.4 6.2 2.6 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Glyco_transf_28 PF03033.15 KZN86409.1 - 3.6e-23 81.8 0.0 9.3e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KZN86409.1 - 0.032 12.7 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KZN86409.1 - 0.075 13.1 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 ATG C terminal domain Transferase PF02458.10 KZN86410.1 - 1.3e-32 112.8 0.0 2.1e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 KZN86410.1 - 0.00043 19.2 0.0 0.00089 18.1 0.0 1.5 1 0 0 1 1 1 1 Condensation domain p450 PF00067.17 KZN86411.1 - 3.5e-69 233.5 0.0 4.7e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KZN86412.1 - 4.2e-18 65.1 46.4 2.5e-11 42.9 22.1 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN86412.1 - 1.3e-14 53.3 12.8 1.8e-14 52.8 8.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.16 KZN86414.1 - 1.1e-10 41.3 0.2 7.7e-07 28.7 0.3 2.6 1 1 2 3 3 3 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN86414.1 - 2.4e-08 34.3 0.2 4.9e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KZN86414.1 - 7.6e-08 31.8 0.3 1.2e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN86414.1 - 1.5e-07 31.6 1.4 2e-07 31.1 0.4 1.8 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN86414.1 - 1.2e-05 24.4 0.1 2.6e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KZN86414.1 - 0.00051 19.1 0.3 0.00066 18.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KZN86414.1 - 0.00074 18.5 0.2 0.0014 17.6 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KZN86414.1 - 0.00093 17.9 0.1 0.0021 16.8 0.1 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 KZN86414.1 - 0.0032 17.9 0.1 0.0062 17.0 0.1 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 KZN86414.1 - 0.0039 16.1 0.2 0.018 13.9 0.2 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.15 KZN86414.1 - 0.0055 16.6 0.0 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KZN86414.1 - 0.03 14.8 0.2 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NUC173 PF08161.7 KZN86415.1 - 7.4e-77 257.1 0.0 4.4e-75 251.3 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 KZN86415.1 - 0.082 13.0 2.0 22 5.4 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Abi_C PF14355.1 KZN86415.1 - 0.091 12.7 0.1 2.3 8.2 0.0 3.1 3 0 0 3 3 3 0 Abortive infection C-terminus CDC45 PF02724.9 KZN86415.1 - 8.4 4.2 8.8 20 3.0 6.1 1.5 1 0 0 1 1 1 0 CDC45-like protein LSM PF01423.17 KZN86416.1 - 9.9e-13 47.4 0.1 1.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain zf-H2C2_2 PF13465.1 KZN86417.1 - 9.6e-10 38.2 16.3 1.1e-05 25.4 2.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KZN86417.1 - 1.6e-07 31.2 16.5 0.0013 18.9 1.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN86417.1 - 0.0002 21.4 16.7 0.013 15.7 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN86417.1 - 4.6 7.4 7.7 0.39 10.9 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SAP30_Sin3_bdg PF13867.1 KZN86418.1 - 5.5e-15 54.9 0.1 1.3e-13 50.6 0.0 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF719 PF05334.8 KZN86418.1 - 0.08 12.9 0.5 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) BRO1 PF03097.13 KZN86419.1 - 1.5e-120 402.4 2.6 1.5e-120 402.4 1.8 2.4 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KZN86419.1 - 2.7e-87 292.4 15.0 2.7e-87 292.4 10.4 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV BLOC1_2 PF10046.4 KZN86419.1 - 0.16 12.0 9.7 5.2 7.2 0.1 5.0 3 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sas10 PF09368.5 KZN86419.1 - 1 9.5 5.6 0.31 11.2 1.1 2.2 2 0 0 2 2 2 0 Sas10 C-terminal domain CTDII PF01556.13 KZN86420.1 - 5.1e-26 90.3 2.1 5.6e-20 71.0 0.2 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KZN86420.1 - 1.7e-23 82.0 4.1 3e-23 81.3 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KZN86420.1 - 6.8e-11 42.0 18.5 1.5e-10 40.9 12.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Lon_C PF05362.8 KZN86421.1 - 4.2e-64 215.6 0.0 8.2e-64 214.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KZN86421.1 - 1.2e-35 123.0 0.0 2.5e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KZN86421.1 - 6.8e-22 78.0 0.0 1.4e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN86421.1 - 2.1e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KZN86421.1 - 2.6e-06 26.9 0.1 9e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KZN86421.1 - 3.7e-06 26.9 0.0 9.7e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 KZN86421.1 - 5.8e-06 25.2 0.2 1.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 KZN86421.1 - 8.5e-06 25.9 0.1 0.00015 21.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN86421.1 - 5.1e-05 24.0 0.1 0.00024 21.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KZN86421.1 - 6.2e-05 23.0 0.0 0.00036 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KZN86421.1 - 0.0003 19.9 0.0 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KZN86421.1 - 0.0021 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN86421.1 - 0.003 17.8 1.7 0.018 15.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 KZN86421.1 - 0.017 14.6 0.1 0.079 12.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KZN86421.1 - 0.02 14.3 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KZN86421.1 - 0.041 13.5 0.1 0.37 10.4 0.0 2.3 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 KZN86421.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 KZN86421.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN86421.1 - 0.059 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KZN86421.1 - 0.063 13.1 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase Phage_connect_1 PF05135.8 KZN86421.1 - 0.065 13.4 0.4 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AAA_24 PF13479.1 KZN86421.1 - 0.091 12.3 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KZN86421.1 - 0.092 12.5 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KZN86421.1 - 0.14 12.4 1.7 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 KZN86421.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ClpB_D2-small PF10431.4 KZN86421.1 - 2.3 8.1 5.8 0.47 10.3 0.2 2.5 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein Pkinase_Tyr PF07714.12 KZN86422.1 - 1.3e-09 37.5 0.0 7.8e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KZN86422.1 - 5.5e-08 32.2 0.0 5.3e-07 29.0 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain cobW PF02492.14 KZN86423.1 - 5.1e-27 94.4 0.0 7.7e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KZN86423.1 - 4.9e-05 22.9 0.0 9.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF1827 PF08860.5 KZN86423.1 - 0.093 12.8 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Mob1_phocein PF03637.12 KZN86424.1 - 1.2e-25 90.1 0.3 2.1e-25 89.3 0.2 1.3 1 0 0 1 1 1 1 Mob1/phocein family HALZ PF02183.13 KZN86424.1 - 0.02 14.5 8.3 0.23 11.2 0.6 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper ORF11CD3 PF10549.4 KZN86424.1 - 0.18 11.5 3.9 0.86 9.3 0.2 2.5 2 0 0 2 2 2 0 ORF11CD3 domain ATP-synt_D PF01813.12 KZN86424.1 - 0.24 10.9 6.1 0.097 12.2 1.7 2.1 2 1 0 2 2 2 0 ATP synthase subunit D HJURP_C PF12347.3 KZN86424.1 - 1.1 8.8 12.5 0.3 10.6 1.5 3.3 2 1 1 3 3 3 0 Holliday junction regulator protein family C-terminal repeat 60KD_IMP PF02096.15 KZN86424.1 - 1.3 8.6 2.8 2.3 7.8 2.0 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein HIT PF01230.18 KZN86425.1 - 7.7e-25 87.2 0.3 1.7e-24 86.1 0.1 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KZN86425.1 - 1.4e-06 28.5 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HD_3 PF13023.1 KZN86426.1 - 2.5e-46 157.4 0.2 3.1e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 KZN86426.1 - 0.0038 17.0 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.17 KZN86426.1 - 0.02 14.8 0.4 0.048 13.6 0.3 1.7 1 1 0 1 1 1 0 HD domain HAUS6_N PF14661.1 KZN86427.1 - 3.1e-50 170.8 0.1 5e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ank_2 PF12796.2 KZN86428.1 - 5.9e-71 234.8 10.7 1.4e-17 63.8 0.1 5.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN86428.1 - 1.3e-42 139.5 3.1 0.0027 17.7 0.0 11.6 11 0 0 11 11 11 9 Ankyrin repeat Ank PF00023.25 KZN86428.1 - 7.6e-42 139.0 17.5 0.00054 19.6 0.0 11.7 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KZN86428.1 - 1.6e-35 120.8 3.9 5e-09 36.4 0.1 8.3 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN86428.1 - 1.3e-31 107.9 12.3 6.9e-05 22.9 0.1 10.1 1 1 8 10 10 10 9 Ankyrin repeats (many copies) NACHT PF05729.7 KZN86428.1 - 2.6e-08 33.6 1.1 6.1e-08 32.4 0.4 2.0 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.1 KZN86428.1 - 8.9e-06 25.8 0.6 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN86428.1 - 0.00074 19.6 0.0 0.0067 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KZN86428.1 - 0.0042 17.2 0.0 1.2 9.2 0.0 2.9 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KZN86428.1 - 0.008 16.4 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 KZN86428.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KZN86428.1 - 0.058 13.6 0.0 0.26 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KZN86428.1 - 0.081 12.8 0.0 0.27 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 KZN86428.1 - 0.17 11.7 2.9 5 6.9 0.0 3.3 3 0 0 3 3 3 0 Adenylate kinase DUF676 PF05057.9 KZN86429.1 - 4.7e-05 22.7 0.0 0.00011 21.5 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KZN86429.1 - 0.00036 20.2 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Spt4 PF06093.8 KZN86429.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Abhydrolase_5 PF12695.2 KZN86429.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KZN86429.1 - 0.023 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 KZN86429.1 - 0.049 13.5 0.0 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glucodextran_N PF09137.6 KZN86430.1 - 0.075 12.2 0.1 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain N NOA36 PF06524.7 KZN86432.1 - 2.6 7.2 5.5 4 6.6 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein BAF1_ABF1 PF04684.8 KZN86432.1 - 8.5 5.0 9.1 18 4.0 6.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CoA_binding_2 PF13380.1 KZN86433.1 - 1.1e-26 93.2 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.10 KZN86434.1 - 4.4e-34 116.9 0.0 1.2e-33 115.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KZN86434.1 - 1.1e-28 98.7 0.1 2e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KZN86434.1 - 3.3e-16 58.5 0.0 7.1e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KZN86434.1 - 3e-15 56.2 0.7 1.6e-14 53.9 0.1 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KZN86434.1 - 0.00078 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily Dioxygenase_C PF00775.16 KZN86435.1 - 1.5e-08 34.1 1.1 1.9e-08 33.7 0.1 1.9 2 1 0 2 2 2 1 Dioxygenase Sugar_tr PF00083.19 KZN86436.1 - 3.2e-131 438.0 28.9 3.7e-131 437.8 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86436.1 - 6.4e-29 100.7 53.1 1.1e-24 86.8 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN86436.1 - 0.0046 15.2 9.9 0.0081 14.4 2.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3154 PF11351.3 KZN86436.1 - 0.04 13.6 0.4 0.04 13.6 0.3 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3154) PIRT PF15099.1 KZN86436.1 - 0.3 10.2 7.1 0.91 8.7 2.7 2.6 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family MFS_1_like PF12832.2 KZN86436.1 - 1 9.1 10.7 0.22 11.3 0.2 3.8 3 0 0 3 3 3 0 MFS_1 like family Ank_2 PF12796.2 KZN86437.1 - 1e-52 176.4 0.8 5.7e-13 49.0 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN86437.1 - 2.5e-43 143.7 12.0 2.1e-06 27.2 0.0 10.1 9 2 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 KZN86437.1 - 9.7e-35 115.1 5.8 0.0012 18.8 0.0 10.4 10 1 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KZN86437.1 - 9e-33 112.0 5.7 1.3e-06 28.6 0.0 7.0 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN86437.1 - 2.8e-31 106.8 9.7 1.6e-05 25.0 0.0 8.4 3 2 5 9 9 9 8 Ankyrin repeats (many copies) Chitin_bind_3 PF03067.10 KZN86440.1 - 7.5e-10 39.3 0.0 2.8e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Chitin binding domain AA_permease_2 PF13520.1 KZN86441.1 - 4.1e-45 154.0 50.0 5.5e-45 153.6 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN86441.1 - 1.1e-10 40.5 48.7 3e-10 39.0 33.8 1.7 1 1 0 1 1 1 1 Amino acid permease TraH PF06122.6 KZN86441.1 - 0.26 10.0 0.5 0.39 9.4 0.3 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein adh_short PF00106.20 KZN86443.1 - 8.6e-25 87.5 1.3 1.2e-24 87.1 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86443.1 - 1.3e-18 67.6 0.0 1.6e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86443.1 - 1.5e-08 34.5 0.4 2.4e-08 33.8 0.3 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KZN86443.1 - 0.0008 19.1 0.1 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KZN86443.1 - 0.0052 17.3 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain THF_DHG_CYH_C PF02882.14 KZN86443.1 - 0.0098 14.9 0.2 0.027 13.5 0.0 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 KZN86443.1 - 0.01 14.8 0.1 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 KZN86443.1 - 0.02 14.6 0.5 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KZN86443.1 - 0.052 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN86443.1 - 0.053 13.5 0.9 0.11 12.5 0.4 1.7 1 1 0 1 1 1 0 NADH(P)-binding Gln-synt_C PF00120.19 KZN86444.1 - 2.2e-60 204.0 0.0 2.7e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.17 KZN86445.1 - 4.3e-233 774.0 0.0 4.8e-233 773.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_3 PF00933.16 KZN86447.1 - 8e-85 284.4 0.0 1.1e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN86447.1 - 2.6e-50 171.0 0.0 9.3e-50 169.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN86447.1 - 2e-22 78.9 0.1 4e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.22 KZN86448.1 - 3e-47 160.3 0.0 1.8e-25 89.8 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KZN86448.1 - 2.1e-15 57.4 6.2 0.00016 21.7 0.0 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 KZN86448.1 - 3.3e-11 42.8 0.6 0.0019 17.4 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KZN86448.1 - 1.4e-06 27.6 0.0 0.075 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KZN86448.1 - 1.5e-06 27.6 1.3 0.047 13.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KZN86448.1 - 3.7e-06 27.4 0.2 0.039 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KZN86448.1 - 3.9e-06 27.3 0.1 0.012 16.0 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein SbcCD_C PF13558.1 KZN86448.1 - 6.2e-06 26.0 0.0 0.11 12.3 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KZN86448.1 - 1.7e-05 24.7 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KZN86448.1 - 3.1e-05 24.7 0.0 0.44 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN86448.1 - 3.5e-05 23.0 0.0 0.22 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 KZN86448.1 - 4.9e-05 22.9 0.1 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.1 KZN86448.1 - 9.8e-05 22.5 0.0 0.073 13.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KZN86448.1 - 0.00018 21.0 1.8 1.1 8.6 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 KZN86448.1 - 0.00024 21.0 1.3 0.26 11.0 0.3 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 KZN86448.1 - 0.00026 20.7 0.0 0.91 9.2 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KZN86448.1 - 0.00035 20.4 0.0 0.25 11.1 0.0 3.4 3 0 0 3 3 3 1 Dynamin family NACHT PF05729.7 KZN86448.1 - 0.0004 20.0 0.1 0.098 12.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KZN86448.1 - 0.0008 19.4 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 KZN86448.1 - 0.0025 18.0 1.4 4.6 7.5 0.1 3.5 3 1 0 3 3 2 0 HEAT repeats ArgK PF03308.11 KZN86448.1 - 0.0027 16.5 0.6 0.78 8.4 0.1 2.3 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 KZN86448.1 - 0.0051 16.6 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN86448.1 - 0.0061 16.7 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase CLASP_N PF12348.3 KZN86448.1 - 0.0068 15.7 0.0 0.44 9.8 0.2 2.4 2 0 0 2 2 2 1 CLASP N terminal FtsK_SpoIIIE PF01580.13 KZN86448.1 - 0.0071 15.8 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family HEAT PF02985.17 KZN86448.1 - 0.012 15.6 0.6 23 5.4 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat AAA PF00004.24 KZN86448.1 - 0.013 15.7 0.0 0.56 10.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KZN86448.1 - 0.023 13.6 0.1 2.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KZN86448.1 - 0.023 14.1 0.0 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 KZN86448.1 - 0.024 13.1 0.1 2.4 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KZN86448.1 - 0.035 13.6 0.1 15 5.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KZN86448.1 - 0.038 14.2 0.0 12 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KZN86448.1 - 0.038 13.3 0.0 7.2 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KZN86448.1 - 0.062 13.2 0.0 3.5 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ipi1_N PF12333.3 KZN86448.1 - 0.064 13.2 0.0 34 4.4 0.0 3.4 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DNA_ligase_OB_2 PF14743.1 KZN86448.1 - 0.065 12.9 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 DNA ligase OB-like domain Septin PF00735.13 KZN86448.1 - 0.12 11.4 0.1 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Septin DUF3584 PF12128.3 KZN86448.1 - 0.37 8.0 0.4 2.2 5.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Citrate_synt PF00285.16 KZN86449.1 - 2.3e-99 332.5 0.0 2.7e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Wyosine_form PF08608.7 KZN86449.1 - 0.11 12.6 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Wyosine base formation AMP-binding PF00501.23 KZN86450.1 - 3.3e-76 256.3 0.0 4.1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN86450.1 - 2.2e-10 41.3 0.0 7.2e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BATS PF06968.8 KZN86451.1 - 1.3e-27 95.4 0.0 9.2e-27 92.7 0.0 2.3 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KZN86451.1 - 1.5e-16 61.0 0.1 3e-16 60.0 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily FAD_binding_4 PF01565.18 KZN86453.1 - 1.7e-19 69.7 1.3 6.5e-19 67.7 0.9 2.1 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN86453.1 - 9.8e-12 44.5 0.4 9.8e-12 44.5 0.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like Aa_trans PF01490.13 KZN86454.1 - 4.4e-38 130.8 31.3 5.7e-38 130.4 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 KZN86454.1 - 1.6e-06 27.0 15.3 1.6e-06 27.0 10.6 1.9 2 0 0 2 2 2 1 Spore germination protein Neurensin PF14927.1 KZN86454.1 - 0.03 13.7 0.4 0.03 13.7 0.3 1.8 2 0 0 2 2 2 0 Neurensin Aminotran_3 PF00202.16 KZN86455.1 - 1.1e-38 133.0 0.0 3.7e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KZN86455.1 - 2.6e-37 128.3 0.0 5.8e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KZN86455.1 - 0.0032 16.9 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.16 KZN86456.1 - 4.5e-35 121.2 0.0 5.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 KZN86456.1 - 0.00099 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 KZN86456.1 - 0.0045 15.7 0.0 0.23 10.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_3 PF00202.16 KZN86456.1 - 0.0086 14.9 0.0 0.042 12.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 KZN86456.1 - 0.066 11.4 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme E1-E2_ATPase PF00122.15 KZN86457.1 - 2e-63 213.5 2.0 4e-63 212.5 1.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN86457.1 - 2.3e-33 115.2 8.6 2.3e-33 115.2 5.9 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN86457.1 - 8.4e-29 101.5 0.0 2.1e-27 96.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN86457.1 - 1.3e-18 66.2 0.0 3.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KZN86457.1 - 1.4e-15 56.9 0.0 3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN86457.1 - 3e-12 47.1 0.0 7.9e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 KZN86457.1 - 6.2e-05 21.7 7.8 0.00037 19.1 0.3 3.0 3 0 0 3 3 3 2 DctM-like transporters Hydrolase_3 PF08282.7 KZN86457.1 - 0.0007 19.2 0.2 0.012 15.2 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.1 KZN86458.1 - 2e-10 40.3 9.6 9.6e-09 34.9 2.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 KZN86458.1 - 1.6e-09 37.7 10.3 4.3e-08 33.1 7.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN86458.1 - 2.3e-07 30.5 1.5 2.3e-07 30.5 1.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KZN86458.1 - 7.9e-06 25.8 8.5 4.3e-05 23.4 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN86458.1 - 1.4e-05 24.6 2.6 1.4e-05 24.6 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN86458.1 - 2.6e-05 23.8 2.3 2.6e-05 23.8 1.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN86458.1 - 8.2e-05 22.1 2.1 8.2e-05 22.1 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN86458.1 - 0.012 15.3 0.5 0.012 15.3 0.3 2.8 2 1 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 KZN86458.1 - 0.025 14.2 6.0 0.045 13.4 2.1 2.4 2 1 0 2 2 2 0 PHD-finger RINGv PF12906.2 KZN86458.1 - 0.036 14.1 2.1 0.036 14.1 1.5 2.6 2 1 1 3 3 3 0 RING-variant domain zf-C2H2_3 PF13878.1 KZN86458.1 - 0.083 12.4 2.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO FANCL_C PF11793.3 KZN86458.1 - 0.28 11.1 11.7 3.2 7.7 4.7 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain GAGA PF09237.6 KZN86458.1 - 0.32 10.6 3.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 GAGA factor zf-C3HC4_4 PF15227.1 KZN86458.1 - 0.49 10.3 10.9 0.62 9.9 0.8 2.8 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KZN86458.1 - 2 8.0 9.9 0.11 12.0 1.9 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 KZN86458.1 - 3.3 7.2 4.8 2.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif dCMP_cyt_deam_1 PF00383.17 KZN86459.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pectinesterase PF01095.14 KZN86460.1 - 2.5e-54 183.8 5.1 3.3e-54 183.4 3.6 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.12 KZN86461.1 - 6.3e-55 186.4 12.9 7.8e-55 186.0 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MmgE_PrpD PF03972.9 KZN86462.1 - 3.9e-150 499.9 0.0 4.6e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DNA_methylase PF00145.12 KZN86463.1 - 2.3e-40 138.7 0.0 2.3e-27 95.9 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MTS PF05175.9 KZN86463.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain GATase_2 PF00310.16 KZN86464.1 - 1.3e-20 73.4 0.0 5.2e-15 55.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KZN86464.1 - 1.4e-14 54.1 0.0 4.4e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KZN86464.1 - 1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KZN86464.1 - 1.1e-12 47.7 0.1 2.6e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KZN86464.1 - 1.4e-06 27.2 0.0 2.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 KZN86464.1 - 0.032 13.5 0.0 0.086 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase HhH-GPD PF00730.20 KZN86465.1 - 7.5e-08 32.6 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Roughex PF06020.6 KZN86465.1 - 0.018 13.7 2.7 0.022 13.4 0.7 1.8 2 0 0 2 2 2 0 Drosophila roughex protein HHH PF00633.18 KZN86465.1 - 0.024 14.3 0.0 0.081 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aldedh PF00171.17 KZN86466.1 - 1.9e-120 402.3 0.0 2.4e-120 401.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.7 KZN86468.1 - 0.0011 18.7 2.3 0.0012 18.5 1.6 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Protocadherin PF08374.6 KZN86468.1 - 0.11 12.1 1.0 0.12 11.9 0.7 1.1 1 0 0 1 1 1 0 Protocadherin Shisa PF13908.1 KZN86468.1 - 1.9 8.5 4.6 1.9 8.6 3.2 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 KZN86468.1 - 4.2 6.9 12.4 0.16 11.5 3.9 2.1 2 1 1 3 3 3 0 Adenovirus E3 region protein CR2 Mt_ATP-synt_D PF05873.7 KZN86470.1 - 3.1e-20 72.4 1.0 3.7e-20 72.1 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Tropomyosin PF00261.15 KZN86470.1 - 0.016 14.2 2.2 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin T2SM_b PF10741.4 KZN86470.1 - 0.025 14.1 0.4 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Spectrin PF00435.16 KZN86470.1 - 0.11 12.8 4.5 0.82 9.9 0.8 2.2 1 1 0 2 2 2 0 Spectrin repeat DUF2408 PF10303.4 KZN86470.1 - 0.14 12.2 0.8 0.23 11.5 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 KZN86470.1 - 0.16 11.9 1.9 6.5 6.7 0.4 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 KZN86470.1 - 0.23 11.2 4.9 13 5.6 1.7 2.4 2 1 1 3 3 3 0 Tropomyosin like DMPK_coil PF08826.5 KZN86470.1 - 1.3 8.9 4.5 0.71 9.8 0.9 2.2 2 1 0 2 2 2 0 DMPK coiled coil domain like NAC PF01849.13 KZN86471.1 - 6.8e-24 83.1 0.0 6.4e-22 76.8 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KZN86471.1 - 0.00013 21.7 0.3 0.00022 20.9 0.2 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CENP-B_dimeris PF09026.5 KZN86471.1 - 0.031 14.5 5.3 9.3 6.5 3.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NESP55 PF06390.7 KZN86471.1 - 0.41 10.0 10.3 0.047 13.0 3.5 1.9 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) CDC45 PF02724.9 KZN86471.1 - 0.47 8.4 9.3 0.02 12.9 2.5 1.5 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.2 KZN86471.1 - 3.6 7.0 11.8 0.67 9.4 5.5 1.6 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_L14e PF01929.12 KZN86472.1 - 4.8e-24 84.4 0.2 7.6e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KZN86472.1 - 2.9e-07 29.9 0.2 5.5e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.10 KZN86473.1 - 4.8e-74 248.5 4.0 5.9e-74 248.2 2.8 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KZN86473.1 - 3.3e-05 23.4 5.0 3.3e-05 23.4 3.4 1.5 2 0 0 2 2 2 1 Yip1 domain Chromate_transp PF02417.10 KZN86473.1 - 0.15 11.6 5.0 0.25 10.9 3.5 1.4 1 0 0 1 1 1 0 Chromate transporter SRP-alpha_N PF04086.8 KZN86474.1 - 2.6e-79 266.4 0.0 3.6e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KZN86474.1 - 1.5e-50 171.3 0.0 2.6e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KZN86474.1 - 3e-07 30.4 0.0 1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KZN86474.1 - 4.9e-07 28.8 0.0 8.9e-07 27.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KZN86474.1 - 9.7e-06 25.1 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KZN86474.1 - 0.0028 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KZN86474.1 - 0.0033 17.1 0.2 0.0098 15.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KZN86474.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN86474.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KZN86474.1 - 0.027 13.8 0.0 0.097 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KZN86474.1 - 0.043 13.7 0.0 0.24 11.3 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KZN86474.1 - 0.043 13.9 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 KZN86474.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.22 KZN86474.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter p450 PF00067.17 KZN86476.1 - 9.5e-45 152.9 0.3 1.6e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ERG4_ERG24 PF01222.12 KZN86477.1 - 8.1e-147 489.2 17.8 1e-146 488.8 12.4 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family p450 PF00067.17 KZN86477.1 - 9.8e-18 63.9 0.0 3.4e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 MFS_1 PF07690.11 KZN86478.1 - 1.8e-41 142.0 38.1 1.7e-35 122.4 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN86478.1 - 1.5e-10 40.2 2.2 1.5e-10 40.2 1.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KZN86478.1 - 8.1e-05 21.1 0.8 8.1e-05 21.1 0.5 3.7 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KZN86478.1 - 0.0032 17.2 0.8 0.085 12.6 0.0 3.4 3 0 0 3 3 3 1 MFS_1 like family TRI12 PF06609.8 KZN86478.1 - 0.014 13.5 0.7 0.025 12.8 0.5 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KZN86478.1 - 0.098 11.1 1.4 0.095 11.1 0.1 1.5 2 0 0 2 2 2 0 Reduced folate carrier Polysacc_lyase PF14099.1 KZN86480.1 - 3.3e-21 75.9 1.2 3.5e-21 75.8 0.8 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF1080 PF06439.6 KZN86480.1 - 0.0054 16.6 0.1 0.0057 16.5 0.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.19 KZN86480.1 - 0.059 13.4 0.1 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain Ank_2 PF12796.2 KZN86481.1 - 0.0049 17.1 0.0 0.07 13.4 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN86481.1 - 0.068 13.4 0.1 7.2 7.1 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 KZN86481.1 - 0.1 12.8 0.0 8.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Rieske PF00355.21 KZN86482.1 - 3e-17 61.9 0.0 5.1e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 KZN86482.1 - 6.1e-08 32.5 0.2 1.9e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Ring_hydroxyl_A PF00848.14 KZN86483.1 - 1.7e-29 103.0 0.6 3.7e-28 98.6 1.0 2.3 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) RabGAP-TBC PF00566.13 KZN86484.1 - 5.3e-39 133.9 0.9 1e-38 132.9 0.7 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KZN86484.1 - 7.8e-12 44.9 0.0 1.2e-07 31.2 0.0 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) GAS2 PF02187.12 KZN86485.1 - 0.0002 21.0 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hexokinase_2 PF03727.11 KZN86486.1 - 3.4e-77 258.9 0.0 4.7e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KZN86486.1 - 3.1e-63 212.8 0.0 4.6e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hus1 PF04005.7 KZN86487.1 - 1.1e-95 319.9 0.0 1.3e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 KZN86488.1 - 3.2e-104 348.6 0.0 4.4e-104 348.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 KZN86488.1 - 5e-66 223.1 22.8 5e-66 223.1 15.8 5.7 4 2 0 5 5 5 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 KZN86488.1 - 1.1e-32 112.4 0.0 2.5e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 KZN86489.1 - 1.1e-19 70.3 0.0 2.6e-18 65.9 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KZN86489.1 - 1.4e-15 58.2 0.0 1.2e-14 55.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN86489.1 - 2.7e-09 37.4 0.1 6.9e-09 36.1 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN86489.1 - 2.6e-06 27.3 0.0 9.6e-06 25.4 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN86489.1 - 0.0039 16.8 0.1 0.0099 15.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cytochrom_B562 PF07361.6 KZN86489.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b562 Ribosomal_L28e PF01778.12 KZN86490.1 - 1e-31 109.7 1.4 2.1e-31 108.7 1.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KZN86490.1 - 7.5e-24 83.7 10.9 7.5e-24 83.7 7.5 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 KZN86490.1 - 1.6e-07 30.8 11.9 1.9e-07 30.5 8.2 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 KZN86490.1 - 0.079 10.8 25.9 0.11 10.4 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 KZN86490.1 - 0.17 10.2 9.8 0.21 9.9 6.8 1.2 1 0 0 1 1 1 0 SGT1 protein CENP-T PF15511.1 KZN86490.1 - 0.18 10.9 13.6 0.24 10.5 9.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Mpp10 PF04006.7 KZN86490.1 - 1.6 7.0 27.2 8.7 4.5 0.0 2.1 1 1 1 2 2 2 0 Mpp10 protein TFIIF_alpha PF05793.7 KZN86490.1 - 3 6.1 24.4 4.8 5.4 16.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Stm1_N PF09598.5 KZN86490.1 - 3.9 8.2 14.1 2.8 8.6 5.1 2.4 2 0 0 2 2 2 0 Stm1 CDC45 PF02724.9 KZN86490.1 - 6.2 4.7 20.1 7.3 4.4 11.1 2.0 2 0 0 2 2 2 0 CDC45-like protein Mso1_Sec1_bdg PF14475.1 KZN86491.1 - 2.6e-10 39.5 0.0 4.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sugar_tr PF00083.19 KZN86492.1 - 1.5e-85 287.4 19.4 1.8e-85 287.2 13.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86492.1 - 5.4e-29 101.0 22.8 5.4e-29 101.0 15.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN86492.1 - 3.5e-08 32.1 5.6 1.2e-07 30.3 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KZN86492.1 - 0.029 12.4 3.2 0.072 11.1 2.2 1.6 1 0 0 1 1 1 0 Transmembrane secretion effector DUF1228 PF06779.9 KZN86492.1 - 0.68 9.9 12.0 1.4 9.0 0.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) DUF3638 PF12340.3 KZN86493.1 - 1.4e-100 335.0 0.3 2.9e-100 333.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KZN86493.1 - 3.2e-16 58.1 0.5 7e-16 57.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) GUCT PF08152.7 KZN86493.1 - 0.09 12.7 0.1 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 GUCT (NUC152) domain OTT_1508_deam PF14441.1 KZN86494.1 - 1.3e-13 50.9 0.3 2.6e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Fig1 PF12351.3 KZN86496.1 - 7.5e-28 97.6 0.1 9.3e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 AA_permease PF00324.16 KZN86496.1 - 0.023 13.0 0.2 0.029 12.7 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease DUF3317 PF11779.3 KZN86496.1 - 0.18 11.2 2.5 0.46 9.9 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3317) AATase PF07247.7 KZN86497.1 - 3.2e-17 62.2 0.0 5.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase CorA PF01544.13 KZN86497.1 - 1.7e-08 33.8 0.7 1.7e-08 33.8 0.5 3.0 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein WES_acyltransf PF03007.11 KZN86497.1 - 0.0008 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain SKG6 PF08693.5 KZN86497.1 - 7.6 5.9 11.6 7.9 5.8 3.3 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Oxidored_FMN PF00724.15 KZN86498.1 - 2.5e-95 319.3 0.0 2.8e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family YscK PF06578.7 KZN86500.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Glyoxalase PF00903.20 KZN86501.1 - 2.6e-09 37.1 3.1 7.6e-08 32.3 0.9 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KZN86501.1 - 4e-09 37.0 0.4 0.0036 17.8 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain UreD PF01774.12 KZN86502.1 - 3.8e-52 176.7 0.0 4.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Amidohydro_1 PF01979.15 KZN86503.1 - 6.5e-61 206.8 1.2 1.1e-60 206.0 0.9 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KZN86503.1 - 4.2e-52 175.3 1.2 8.1e-52 174.4 0.8 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KZN86503.1 - 8.6e-39 131.4 0.0 1.8e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 KZN86503.1 - 1.5e-13 50.6 0.1 3.5e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KZN86503.1 - 1.5e-08 34.3 4.1 5e-08 32.6 2.8 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN86503.1 - 9.9e-05 21.7 0.0 0.0022 17.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KZN86503.1 - 0.0048 16.9 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase DUF3402 PF11882.3 KZN86504.1 - 2e-163 544.2 0.0 2.6e-163 543.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KZN86504.1 - 2.6e-91 305.5 0.0 4e-91 304.9 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 KZN86505.1 - 1.7e-15 56.8 2.1 1.7e-15 56.8 1.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 KZN86505.1 - 0.041 13.5 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF4131 PF13567.1 KZN86505.1 - 0.69 9.2 8.0 1.7 8.0 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 KZN86505.1 - 8 6.7 7.8 17 5.6 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) RWD PF05773.17 KZN86506.1 - 2.9e-20 72.2 0.0 4.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KZN86506.1 - 4.6e-16 58.4 44.8 3e-12 46.2 5.3 4.4 3 1 1 4 4 4 2 IBR domain zf-RING_5 PF14634.1 KZN86506.1 - 0.00091 18.9 10.7 0.00091 18.9 7.4 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN86506.1 - 0.0017 18.1 10.1 0.0017 18.1 7.0 3.9 2 1 1 3 3 3 1 Ring finger domain Lipase_GDSL_2 PF13472.1 KZN86507.1 - 1.3e-14 54.7 0.1 1.6e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN86507.1 - 7.3e-10 39.0 0.2 3.3e-09 36.9 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA-synt_2c PF01411.14 KZN86507.1 - 0.13 10.5 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Cofilin_ADF PF00241.15 KZN86508.1 - 2.4e-29 101.7 0.1 2.6e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.2 KZN86509.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like CRT10 PF08728.5 KZN86510.1 - 7.2e-20 70.5 0.0 7.1e-12 44.1 0.0 2.1 2 0 0 2 2 2 2 CRT10 MMtag PF10159.4 KZN86511.1 - 3.7e-34 116.6 4.7 6e-34 115.9 3.3 1.4 1 0 0 1 1 1 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 KZN86512.1 - 3.2e-247 822.4 0.0 2.3e-246 819.5 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KZN86512.1 - 0.0013 17.4 3.4 0.0038 15.9 2.0 2.0 1 1 0 1 1 1 1 Trehalase DAO PF01266.19 KZN86513.1 - 2.1e-61 207.7 0.3 2.8e-61 207.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN86513.1 - 1.5e-06 28.1 0.3 3.2e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KZN86513.1 - 0.00011 21.0 0.3 0.0024 16.5 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KZN86513.1 - 0.00055 19.8 1.3 1.3 8.8 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN86513.1 - 0.0056 17.0 0.6 0.012 15.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN86513.1 - 0.0057 16.4 0.5 0.072 12.8 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KZN86513.1 - 0.0065 15.5 0.2 0.012 14.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KZN86513.1 - 0.0089 14.9 0.6 0.85 8.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Mqo PF06039.10 KZN86513.1 - 0.022 12.9 0.0 0.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Strep_67kDa_ant PF06100.6 KZN86513.1 - 0.12 10.6 0.1 0.2 9.9 0.1 1.3 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DUF1777 PF08648.7 KZN86514.1 - 3.5e-22 79.0 73.5 1.5e-18 67.1 50.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) AMP-binding PF00501.23 KZN86515.1 - 2.9e-80 269.7 0.0 4.8e-80 268.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KZN86515.1 - 7.3e-35 120.0 0.0 1.3e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 KZN86515.1 - 3.1e-09 37.6 0.1 1.6e-08 35.3 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KZN86515.1 - 5.6e-06 25.9 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN86515.1 - 0.042 14.1 0.1 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Zn_clus PF00172.13 KZN86516.1 - 3.2e-07 30.1 12.2 6.5e-07 29.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 KZN86517.1 - 1.4e-95 320.3 0.7 3.9e-95 318.8 0.2 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_42C PF08533.5 KZN86517.1 - 0.096 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.19 KZN86518.1 - 2.5e-81 273.5 20.5 2.9e-81 273.3 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86518.1 - 2.5e-16 59.3 27.8 8.1e-16 57.6 15.8 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Elong_Iki1 PF10483.4 KZN86519.1 - 3.6e-93 311.9 0.0 4.2e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 KZN86520.1 - 2.1e-28 97.6 0.8 3.3e-28 97.0 0.5 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KZN86520.1 - 7.5e-15 54.3 0.0 1.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 KZN86520.1 - 0.11 12.2 0.5 0.24 11.0 0.1 1.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD PilJ PF13675.1 KZN86520.1 - 0.24 11.7 3.3 0.73 10.1 0.3 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ASXH PF13919.1 KZN86521.1 - 1.4e-38 131.8 0.5 2.8e-38 130.8 0.4 1.5 1 0 0 1 1 1 1 Asx homology domain adh_short PF00106.20 KZN86522.1 - 7.6e-15 55.2 0.1 1.4e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86522.1 - 5.7e-08 32.8 0.0 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86522.1 - 7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain CLPTM1 PF05602.7 KZN86523.1 - 5e-170 565.9 0.0 5.9e-170 565.7 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Toxin_51 PF15531.1 KZN86523.1 - 0.093 12.5 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative toxin 51 DUF1240 PF06836.7 KZN86523.1 - 0.15 12.2 3.8 0.36 11.0 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) CENP-I PF07778.6 KZN86524.1 - 3.5e-92 309.2 1.1 5e-92 308.7 0.8 1.1 1 0 0 1 1 1 1 Mis6 Transcrip_reg PF01709.15 KZN86525.1 - 1.1e-62 211.2 0.4 1.2e-62 211.0 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.1 KZN86526.1 - 6.6e-14 51.9 1.6 0.00064 19.9 0.0 7.3 7 1 1 8 8 8 4 HEAT repeats HEAT PF02985.17 KZN86526.1 - 1.1e-09 37.5 11.7 0.058 13.5 0.0 9.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 KZN86526.1 - 0.0056 17.1 6.6 33 5.1 0.0 6.9 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 KZN86526.1 - 0.016 15.0 2.3 24 4.7 0.1 5.3 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Transp_cyt_pur PF02133.10 KZN86528.1 - 7.4e-26 90.6 38.7 1.2e-25 89.9 26.8 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Arylsulfotran_2 PF14269.1 KZN86529.1 - 6.7e-14 51.7 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN86529.1 - 1.6e-13 50.0 0.9 3.8e-08 32.2 0.1 3.6 2 2 1 3 3 3 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KZN86529.1 - 0.00081 18.9 0.1 0.0075 15.7 0.1 2.2 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KZN86529.1 - 0.091 12.3 1.2 3.8 7.2 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat DUF1640 PF07798.6 KZN86530.1 - 3e-13 50.2 5.1 4.8e-13 49.5 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 KZN86530.1 - 0.083 11.5 0.9 0.13 10.9 0.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter UvrD-helicase PF00580.16 KZN86531.1 - 1.5e-12 47.5 0.0 1.5e-08 34.2 0.0 2.8 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KZN86531.1 - 1.6e-09 37.7 0.1 3.4e-07 30.0 0.0 3.1 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 KZN86531.1 - 3.5e-06 27.0 0.1 4.2e-05 23.6 0.1 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain SNAP PF14938.1 KZN86531.1 - 6.5e-06 25.4 3.1 2.2e-05 23.7 2.2 1.9 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Clathrin PF00637.15 KZN86531.1 - 0.0057 16.2 0.7 0.2 11.2 0.1 3.4 2 2 1 3 3 3 1 Region in Clathrin and VPS TPR_11 PF13414.1 KZN86531.1 - 0.036 13.7 9.9 7.4 6.3 0.1 3.9 2 1 2 4 4 4 0 TPR repeat AAA_12 PF13087.1 KZN86531.1 - 0.036 13.4 0.0 0.46 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KZN86531.1 - 0.1 12.1 0.2 9.6 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.12 KZN86531.1 - 0.27 11.2 15.2 5.4 7.1 0.2 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86531.1 - 0.41 10.5 6.8 55 3.8 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86531.1 - 1.6 8.7 4.4 10 6.1 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86531.1 - 4.7 6.9 10.0 3 7.5 0.1 4.7 4 1 0 5 5 5 0 Tetratricopeptide repeat Vps51 PF08700.6 KZN86532.1 - 4.7e-15 55.2 0.0 5.5e-14 51.7 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 YbaB_DNA_bd PF02575.11 KZN86532.1 - 0.0086 15.9 0.0 0.073 12.9 0.0 2.4 2 0 0 2 2 2 1 YbaB/EbfC DNA-binding family APH PF01636.18 KZN86532.1 - 0.048 13.3 0.3 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family NPV_P10 PF05531.7 KZN86532.1 - 3.1 8.0 7.5 7.6 6.8 0.0 4.5 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein D123 PF07065.9 KZN86533.1 - 9.2e-89 297.4 0.0 7.3e-86 287.9 0.0 2.1 1 1 1 2 2 2 2 D123 DUF2392 PF10288.4 KZN86533.1 - 0.039 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ECH PF00378.15 KZN86534.1 - 3.7e-27 95.0 0.0 4.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 KZN86535.1 - 0.00067 19.4 2.5 0.0013 18.5 1.7 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) TMEM247 PF15444.1 KZN86535.1 - 0.083 12.7 0.8 0.096 12.4 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DUF3317 PF11779.3 KZN86536.1 - 3.8e-22 77.4 6.1 6e-22 76.8 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 KZN86537.1 - 1.4e-26 92.5 0.8 2.5e-26 91.7 0.5 1.3 1 0 0 1 1 1 1 RF-1 domain Paf1 PF03985.8 KZN86537.1 - 0.07 11.8 4.7 0.087 11.5 3.3 1.1 1 0 0 1 1 1 0 Paf1 E3_binding PF02817.12 KZN86537.1 - 0.074 12.6 1.2 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 e3 binding domain AAL_decarboxy PF03306.8 KZN86537.1 - 0.16 10.9 0.2 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase CAS_CSE1 PF03378.10 KZN86538.1 - 3.1e-185 615.6 1.2 6.5e-185 614.5 0.8 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KZN86538.1 - 6.2e-157 521.9 0.9 9.2e-157 521.3 0.6 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KZN86538.1 - 5.3e-13 48.6 0.1 2.6e-12 46.4 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KZN86538.1 - 0.0084 16.0 2.0 0.63 9.9 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 KZN86538.1 - 0.026 14.7 0.0 0.85 9.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats DUF1529 PF07485.6 KZN86538.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) CTP_synth_N PF06418.9 KZN86539.1 - 4e-117 390.2 0.1 5.3e-117 389.8 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KZN86539.1 - 5.9e-53 179.1 0.0 1e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN86539.1 - 1.5e-07 31.0 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KZN86539.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3384 PF11864.3 KZN86540.1 - 2.7e-97 326.1 1.6 3.6e-97 325.7 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KZN86540.1 - 8.1e-50 168.8 0.0 1.6e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KZN86540.1 - 4.5e-32 111.5 0.0 5.2e-30 104.7 0.0 2.7 3 0 0 3 3 3 2 Tuberin Fungal_trans PF04082.13 KZN86541.1 - 0.00045 19.1 0.3 0.00081 18.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1667 PF07892.6 KZN86541.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Zn_clus PF00172.13 KZN86541.1 - 0.3 11.0 6.2 0.043 13.7 1.2 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 KZN86542.1 - 4.3e-44 150.0 5.8 4.3e-44 150.0 4.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.7 KZN86542.1 - 0.0067 16.2 0.6 0.014 15.3 0.4 1.6 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Phosphodiest PF01663.17 KZN86543.1 - 3.9e-14 52.7 0.8 7.1e-14 51.9 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KZN86543.1 - 4.8e-07 29.4 0.6 8.2e-07 28.6 0.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KZN86543.1 - 6.5e-06 25.5 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Gly-zipper_OmpA PF13436.1 KZN86543.1 - 0.4 10.3 4.6 0.94 9.1 3.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 KZN86543.1 - 1.6 8.2 13.3 5 6.7 9.2 1.8 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KZN86543.1 - 2 8.1 14.0 5.1 6.8 9.7 1.7 1 0 0 1 1 1 0 Glycine zipper SP_C-Propep PF08999.5 KZN86544.1 - 0.041 13.3 1.6 0.045 13.2 0.1 1.7 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide PUF PF00806.14 KZN86545.1 - 9.6e-61 197.9 11.9 7e-10 37.8 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KZN86545.1 - 0.076 13.2 2.0 4.3 7.6 0.1 4.3 4 2 1 5 5 5 0 Protein of unknown function DUF260 DUF234 PF03008.9 KZN86545.1 - 0.23 11.6 0.9 1.8 8.7 0.1 2.7 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function cwf21 PF08312.7 KZN86546.1 - 1.5e-14 53.5 26.9 1.5e-14 53.5 18.7 2.7 2 1 0 2 2 2 1 cwf21 domain DUF3040 PF11239.3 KZN86546.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) HA2 PF04408.18 KZN86547.1 - 3.7e-21 75.0 0.0 1.3e-20 73.2 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN86547.1 - 1.6e-14 53.4 0.0 5.8e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KZN86547.1 - 2.8e-11 43.2 0.0 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KZN86547.1 - 7.2e-09 35.3 0.0 5.6e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN86547.1 - 0.00066 19.8 0.4 0.0049 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KZN86547.1 - 0.0064 15.4 0.1 0.053 12.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 KZN86547.1 - 0.069 12.9 9.2 1.4 8.7 0.0 3.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KZN86547.1 - 0.092 12.6 0.0 1.1 9.1 0.0 2.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KZN86547.1 - 0.11 12.1 3.9 0.35 10.5 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KZN86547.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.7 4 1 0 4 4 4 0 AAA domain DUF2372 PF10178.4 KZN86548.1 - 0.003 17.6 0.0 0.0069 16.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) Tyr-DNA_phospho PF06087.7 KZN86550.1 - 5.6e-67 226.2 0.0 8.6e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KZN86550.1 - 2.8e-05 23.8 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 KZN86550.1 - 0.00017 20.8 6.8 0.0013 18.1 0.1 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif ABC2_membrane PF01061.19 KZN86551.1 - 3e-88 294.4 55.4 1.9e-47 161.1 14.4 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN86551.1 - 4.7e-39 133.8 0.1 1e-20 74.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KZN86551.1 - 7.4e-32 109.0 1.7 5.1e-27 93.5 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KZN86551.1 - 3.9e-08 33.2 0.2 1.4e-07 31.4 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KZN86551.1 - 1.1e-05 25.3 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KZN86551.1 - 1.2e-05 25.4 0.0 0.3 11.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain cobW PF02492.14 KZN86551.1 - 1.4e-05 24.6 0.1 0.00013 21.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KZN86551.1 - 4.5e-05 22.7 0.0 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN86551.1 - 4.5e-05 22.9 0.1 0.19 11.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KZN86551.1 - 5.8e-05 23.2 0.0 0.084 13.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KZN86551.1 - 8.2e-05 22.0 0.1 0.23 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN86551.1 - 0.00013 21.9 0.7 0.014 15.3 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 KZN86551.1 - 0.00014 22.6 0.0 0.0045 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KZN86551.1 - 0.00033 20.1 0.1 1.1 8.7 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KZN86551.1 - 0.00053 19.9 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 KZN86551.1 - 0.0012 18.4 1.7 0.095 12.3 0.4 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KZN86551.1 - 0.0016 18.7 4.6 0.0035 17.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KZN86551.1 - 0.0025 17.8 0.1 0.0025 17.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 KZN86551.1 - 0.0035 16.5 0.1 0.061 12.5 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KZN86551.1 - 0.0053 16.4 0.8 0.26 10.9 0.3 2.5 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 KZN86551.1 - 0.014 15.8 0.1 0.66 10.4 0.0 3.2 3 0 0 3 3 2 0 Miro-like protein AAA PF00004.24 KZN86551.1 - 0.033 14.4 0.1 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KZN86551.1 - 0.058 12.2 0.2 3.7 6.3 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_24 PF13479.1 KZN86551.1 - 0.061 12.8 0.2 0.61 9.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KZN86551.1 - 0.078 11.8 0.5 6.1 5.6 0.2 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 KZN86551.1 - 0.089 12.2 2.1 3.3 7.0 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 KZN86551.1 - 0.1 11.5 0.5 0.31 9.9 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_19 PF13245.1 KZN86551.1 - 0.22 11.3 1.9 21 4.9 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 KZN86551.1 - 0.24 10.8 0.6 0.5 9.8 0.2 1.6 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation DUF2085 PF09858.4 KZN86551.1 - 0.37 10.8 6.9 0.54 10.3 0.1 4.0 4 0 0 4 4 3 0 Predicted membrane protein (DUF2085) CDP-OH_P_transf PF01066.16 KZN86552.1 - 1.5e-17 63.7 4.6 3e-17 62.7 3.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MFS_1_like PF12832.2 KZN86552.1 - 0.023 14.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 MFS_1 like family Gti1_Pac2 PF09729.4 KZN86554.1 - 1.9e-62 210.0 0.0 4.7e-62 208.7 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family GIDA PF01134.17 KZN86555.1 - 2.6e-154 513.8 0.0 3.1e-154 513.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KZN86555.1 - 2e-19 69.4 0.0 5.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KZN86555.1 - 9.9e-07 28.8 1.2 2e-06 27.8 0.8 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN86555.1 - 1.9e-06 27.2 1.8 3.3e-06 26.4 1.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KZN86555.1 - 0.00012 21.1 3.9 0.17 10.7 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN86555.1 - 0.0012 17.8 2.2 0.0012 17.8 1.5 1.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 KZN86555.1 - 0.0022 17.5 0.7 0.0036 16.8 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KZN86555.1 - 0.021 13.3 0.6 0.23 9.8 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 KZN86555.1 - 0.14 10.7 0.4 5.9 5.3 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KZN86555.1 - 0.18 11.5 0.4 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding ARD PF03079.9 KZN86556.1 - 7e-44 149.5 0.1 9e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KZN86556.1 - 4.5e-09 35.6 0.0 7.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KZN86556.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KZN86556.1 - 0.0041 16.5 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Cupin MFS_1 PF07690.11 KZN86557.1 - 7.4e-29 100.5 19.2 1.1e-26 93.4 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2404 PF10296.4 KZN86557.1 - 0.00044 20.3 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) p450 PF00067.17 KZN86558.1 - 8.2e-62 209.2 0.0 9.8e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KZN86559.1 - 1.9e-24 85.9 1.0 3.1e-24 85.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86559.1 - 2.8e-06 27.1 12.2 4.8e-06 26.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 KZN86560.1 - 4.6e-195 648.8 0.1 6.1e-195 648.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KZN86560.1 - 5.1e-93 311.3 0.0 7.7e-91 304.1 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KZN86560.1 - 4.6e-54 182.5 0.2 5.7e-52 175.7 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KZN86560.1 - 0.038 12.3 0.0 0.43 8.8 0.0 2.1 2 0 0 2 2 2 0 MutL protein Pyr_redox_2 PF07992.9 KZN86561.1 - 6.1e-20 71.9 0.0 9.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN86561.1 - 1.1e-14 54.9 0.1 2.7e-10 40.6 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN86561.1 - 1.5e-06 28.0 0.0 0.086 12.6 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KZN86561.1 - 1.4e-05 24.1 0.2 0.0019 17.1 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN86561.1 - 0.00019 20.4 0.0 0.00046 19.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KZN86561.1 - 0.00022 19.8 0.0 0.0034 15.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KZN86561.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KZN86561.1 - 0.0089 15.1 0.1 0.044 12.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KZN86561.1 - 0.0099 14.7 2.5 0.068 12.0 0.2 2.8 2 1 1 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN86561.1 - 0.024 13.5 0.0 0.77 8.5 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 KZN86561.1 - 0.026 13.6 0.2 0.047 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN86561.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HET PF06985.6 KZN86562.1 - 4.6e-28 98.1 3.2 3.3e-27 95.3 2.2 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1183 PF06682.7 KZN86563.1 - 2.2e-92 310.0 0.2 3e-92 309.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) RCR PF12273.3 KZN86563.1 - 0.043 14.3 0.1 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Myb_DNA-binding PF00249.26 KZN86564.1 - 1.9e-06 27.8 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 KZN86565.1 - 6.4e-27 93.3 8.4 6.4e-27 93.3 5.8 7.2 5 3 3 8 8 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KZN86565.1 - 3.5e-09 36.5 10.0 6.2e-09 35.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN86565.1 - 1.8e-08 33.8 7.1 3e-08 33.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN86565.1 - 5.7e-08 32.2 10.2 1e-07 31.4 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN86565.1 - 5.3e-07 29.3 7.0 9.7e-07 28.5 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN86565.1 - 4.3e-06 26.3 10.3 7.2e-06 25.6 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KZN86565.1 - 3.3e-05 23.4 5.8 9.2e-05 22.0 4.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF1272 PF06906.6 KZN86565.1 - 0.0055 16.5 5.7 0.011 15.5 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DUF3349 PF11829.3 KZN86565.1 - 0.0065 16.8 0.2 0.042 14.2 0.2 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) zf-C3HC4_4 PF15227.1 KZN86565.1 - 0.0074 16.1 6.6 0.014 15.2 4.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KZN86565.1 - 0.016 15.3 4.2 0.018 15.1 1.8 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KZN86565.1 - 0.023 14.2 6.8 0.089 12.3 4.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KZN86565.1 - 0.028 13.9 3.5 0.057 12.9 2.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PLAC9 PF15205.1 KZN86565.1 - 0.09 13.0 0.1 4.7 7.5 0.0 3.3 3 0 0 3 3 2 0 Placenta-specific protein 9 zf-ribbon_3 PF13248.1 KZN86565.1 - 0.11 11.7 2.1 0.25 10.6 1.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KZN86565.1 - 0.18 11.5 2.8 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_6 PF14835.1 KZN86565.1 - 0.32 10.8 3.7 0.72 9.6 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 KZN86565.1 - 0.45 10.3 6.1 1.1 9.1 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 KZN86565.1 - 0.63 9.9 11.6 0.68 9.8 4.5 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_6 PF13912.1 KZN86565.1 - 0.64 10.0 4.5 2.9 7.9 0.3 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KZN86565.1 - 1.1 9.0 5.8 2.7 7.7 1.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KZN86565.1 - 1.9 8.7 5.8 30 4.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Nse PF11789.3 KZN86565.1 - 3.8 7.1 9.1 0.46 10.0 3.1 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_4 PF13894.1 KZN86565.1 - 6.3 7.3 7.3 8.8 6.9 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-FCS PF06467.9 KZN86565.1 - 6.9 6.4 8.7 12 5.6 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UreF PF01730.11 KZN86566.1 - 1.5e-13 51.0 0.3 3.6e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 UreF ABC1 PF03109.11 KZN86567.1 - 9.2e-34 115.9 0.0 2.2e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family ERG4_ERG24 PF01222.12 KZN86568.1 - 1.1e-139 465.7 3.5 1.2e-139 465.5 2.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KZN86568.1 - 0.0002 20.7 0.1 0.0002 20.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) OTT_1508_deam PF14441.1 KZN86569.1 - 1.1e-11 44.7 0.1 2.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_S64 PF08192.6 KZN86570.1 - 0.00053 18.4 0.4 0.024 13.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S32 PF05579.8 KZN86570.1 - 0.011 14.6 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 DUF3716 PF12511.3 KZN86571.1 - 0.0003 20.3 2.9 0.00059 19.3 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Sipho_Gp157 PF05565.6 KZN86573.1 - 0.0097 15.4 0.2 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Siphovirus Gp157 Tmemb_cc2 PF10267.4 KZN86573.1 - 0.021 13.3 2.7 0.033 12.7 1.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cluap1 PF10234.4 KZN86573.1 - 0.067 12.3 0.3 0.095 11.8 0.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.2 KZN86573.1 - 0.14 12.0 3.2 0.22 11.3 2.2 1.2 1 0 0 1 1 1 0 Tropomyosin like GTP_EFTU_D2 PF03144.20 KZN86573.1 - 0.14 12.2 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 ADIP PF11559.3 KZN86573.1 - 0.18 11.7 2.0 0.32 10.8 1.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.3 KZN86573.1 - 0.54 9.2 1.6 0.94 8.4 1.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Mannosyl_trans3 PF11051.3 KZN86574.1 - 2.1e-79 266.6 0.1 1.2e-78 264.2 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative DUF605 PF04652.11 KZN86575.1 - 0.1 11.9 10.6 0.14 11.4 7.3 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_60s PF00428.14 KZN86575.1 - 0.4 11.1 0.1 0.4 11.1 0.1 3.6 2 2 0 2 2 2 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 KZN86575.1 - 2.1 7.2 7.8 1.2 8.1 3.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Fungal_trans_2 PF11951.3 KZN86576.1 - 2.7e-48 164.4 0.8 3.2e-48 164.2 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 KZN86577.1 - 2.3e-41 141.9 0.0 3.3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KZN86577.1 - 1.5e-09 37.4 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KZN86577.1 - 1.1e-05 24.3 0.0 1.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KZN86577.1 - 7.4e-05 21.2 0.0 0.00011 20.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KZN86577.1 - 0.00025 20.1 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Metallothio_11 PF02066.10 KZN86577.1 - 0.056 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Metallothionein family 11 AMPKBI PF04739.10 KZN86579.1 - 7.9e-29 99.4 1.6 1.2e-28 98.9 0.0 2.1 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 KZN86580.1 - 8.4e-86 287.7 0.0 9.7e-86 287.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.23 KZN86581.1 - 4.9e-17 62.7 0.0 5.2e-16 59.3 0.0 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 KZN86581.1 - 3.2e-05 23.8 0.1 8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding EPL1 PF10513.4 KZN86582.1 - 1.9e-32 112.7 0.7 1.9e-32 112.7 0.5 3.1 3 2 0 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KZN86583.1 - 4.5e-26 88.1 13.1 2.4e-07 29.5 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KZN86583.1 - 1.6e-21 76.1 3.3 1.4e-11 44.3 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KZN86583.1 - 7.2e-20 69.0 6.6 4.3e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KZN86583.1 - 5.2e-18 63.5 13.1 1.3e-05 24.3 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KZN86583.1 - 6.7e-14 51.2 13.4 7.7e-05 22.2 0.9 4.3 1 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KZN86583.1 - 1.6e-07 31.3 0.0 0.00044 20.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KZN86583.1 - 0.00031 20.4 7.9 0.3 10.8 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KZN86583.1 - 0.016 15.0 0.1 0.87 9.5 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain Anthrax-tox_M PF09156.5 KZN86583.1 - 0.031 13.3 0.7 0.063 12.3 0.1 1.6 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain ATP-cone PF03477.11 KZN86583.1 - 0.083 13.3 0.4 0.19 12.1 0.3 1.5 1 0 0 1 1 1 0 ATP cone domain PMBR PF09373.5 KZN86583.1 - 0.13 12.2 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat Ribosomal_S9 PF00380.14 KZN86585.1 - 4.7e-35 120.4 0.4 7.1e-35 119.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 KZN86586.1 - 1.7e-41 140.2 0.4 3.1e-41 139.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KZN86586.1 - 1.4e-13 50.6 0.1 2.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KZN86586.1 - 1.9e-10 40.7 0.0 6.2e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN86586.1 - 6.5e-10 38.7 2.3 8.8e-10 38.3 0.1 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN86586.1 - 2.9e-06 27.3 0.0 7.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN86586.1 - 1.5e-05 25.3 0.2 4e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KZN86586.1 - 0.0029 17.5 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 KZN86586.1 - 0.92 9.9 15.5 1.2 9.5 8.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein NIF PF03031.13 KZN86588.1 - 5.7e-23 81.3 0.0 3.4e-22 78.7 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 KZN86589.1 - 6.1e-46 156.3 20.5 6.1e-46 156.3 14.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF947) RNA_pol_L_2 PF13656.1 KZN86591.1 - 1.6e-29 101.1 0.0 2.1e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KZN86591.1 - 3.4e-13 48.4 0.0 4.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 KZN86592.1 - 3.4e-06 27.4 0.1 4.3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KZN86592.1 - 2.4e-05 24.0 0.1 4.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN86592.1 - 0.0001 22.4 0.1 0.00016 21.8 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_6 PF12697.2 KZN86594.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN86594.1 - 3.1e-08 33.4 0.0 8.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN86594.1 - 4.2e-05 23.3 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KZN86594.1 - 0.039 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Cutinase Cohesin_load PF10345.4 KZN86595.1 - 8.1e-171 569.3 1.2 1e-170 568.9 0.8 1.0 1 0 0 1 1 1 1 Cohesin loading factor DUF3323 PF11796.3 KZN86595.1 - 0.001 18.4 1.3 0.001 18.4 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) TPR_12 PF13424.1 KZN86595.1 - 0.067 13.1 11.3 0.24 11.3 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Histone PF00125.19 KZN86596.1 - 1.3e-27 95.7 0.2 1.9e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KZN86596.1 - 0.00054 20.0 0.1 0.00097 19.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KZN86596.1 - 0.023 14.7 0.4 0.023 14.7 0.3 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aminotran_4 PF01063.14 KZN86596.1 - 0.08 12.3 2.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class IV CENP-T PF15511.1 KZN86596.1 - 0.15 11.2 6.8 1.2 8.2 4.7 1.9 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 KZN86597.1 - 6.1e-49 166.1 4.7 7e-49 166.0 3.2 1.0 1 0 0 1 1 1 1 Der1-like family DUF4395 PF14340.1 KZN86597.1 - 1.6 8.8 7.9 0.65 10.0 3.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Gly_transf_sug PF04488.10 KZN86598.1 - 1.7e-18 66.8 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif IGPD PF00475.13 KZN86600.1 - 8.5e-57 191.0 0.5 1.2e-56 190.6 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Pet127 PF08634.5 KZN86602.1 - 1.3e-116 388.5 0.4 2.1e-116 387.9 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 TSP9 PF11493.3 KZN86602.1 - 0.022 15.3 0.4 13 6.4 0.0 2.9 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 GARS_A PF01071.14 KZN86603.1 - 4.6e-81 271.0 0.0 7.2e-81 270.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KZN86603.1 - 3.6e-34 117.2 0.0 1.3e-33 115.4 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KZN86603.1 - 2.4e-30 105.5 0.0 5.9e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KZN86603.1 - 4.9e-27 93.9 0.1 1.1e-26 92.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KZN86603.1 - 4.2e-16 58.9 1.4 1.5e-15 57.1 0.9 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KZN86603.1 - 1.2e-09 38.1 0.0 3.5e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN86603.1 - 7.7e-09 34.7 0.0 1.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KZN86603.1 - 5.5e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KZN86603.1 - 0.00014 21.7 0.0 0.00059 19.7 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KZN86603.1 - 0.00021 20.6 0.9 0.0003 20.1 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 KZN86603.1 - 0.00044 19.6 0.0 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KZN86603.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Actin PF00022.14 KZN86604.1 - 5.9e-158 525.4 0.0 6.7e-158 525.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KZN86604.1 - 0.039 14.3 0.0 0.11 12.9 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 KZN86605.1 - 4.7e-35 119.9 2.7 1.9e-34 117.9 0.7 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KZN86605.1 - 5.2e-10 39.4 0.8 2.4e-06 27.7 0.1 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KZN86605.1 - 7.4e-08 32.6 0.4 0.00044 20.6 0.0 3.0 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 KZN86605.1 - 1.6e-07 30.8 0.1 0.00092 18.9 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KZN86605.1 - 8.4e-05 22.3 0.1 0.0051 16.7 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Adaptin_N PF01602.15 KZN86605.1 - 0.028 12.7 0.0 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Atx10homo_assoc PF09759.4 KZN86605.1 - 0.054 13.2 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain CTNNBL PF08216.6 KZN86605.1 - 0.074 12.6 0.5 0.34 10.5 0.1 2.1 2 1 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear V-ATPase_H_C PF11698.3 KZN86605.1 - 0.13 12.2 0.5 0.96 9.3 0.0 2.1 2 1 1 3 3 3 0 V-ATPase subunit H UPF0220 PF05255.6 KZN86606.1 - 9.6e-69 229.8 2.1 1.1e-68 229.6 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF998 PF06197.8 KZN86606.1 - 1.8e-05 24.1 6.4 2.2e-05 23.8 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) ATP1G1_PLM_MAT8 PF02038.11 KZN86606.1 - 0.016 14.1 0.4 0.07 12.1 0.1 2.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Vps55 PF04133.9 KZN86608.1 - 1.4e-47 160.3 5.3 1.5e-47 160.2 3.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 KZN86608.1 - 0.28 11.2 2.5 0.29 11.2 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Proteasome PF00227.21 KZN86609.1 - 2.2e-49 167.3 0.0 2.8e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KZN86609.1 - 2.8e-12 45.7 0.3 4.3e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.9 KZN86610.1 - 4.9e-29 100.8 0.0 8.8e-29 100.0 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase Med6 PF04934.9 KZN86611.1 - 7.4e-42 142.2 0.1 9.8e-42 141.8 0.1 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Chorismate_bind PF00425.13 KZN86612.1 - 3.6e-63 213.2 0.0 8.3e-61 205.5 0.0 2.8 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 KZN86612.1 - 7.4e-30 103.8 0.0 1.2e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KZN86612.1 - 5.2e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KZN86612.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DUF3684 PF12449.3 KZN86613.1 - 0 1562.2 0.0 0 1562.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KZN86613.1 - 1.8e-05 24.4 0.0 5.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KZN86613.1 - 0.0013 18.3 0.0 0.005 16.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 KZN86613.1 - 2.2 8.1 8.0 0.64 9.8 0.1 2.6 2 1 1 3 3 3 0 WLM domain TRAPPC9-Trs120 PF08626.6 KZN86614.1 - 1.3e-154 516.3 0.0 1.7e-154 515.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Aldedh PF00171.17 KZN86615.1 - 3.7e-128 427.7 0.0 4.2e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IMS_C PF11799.3 KZN86616.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain DUF3430 PF11912.3 KZN86617.1 - 0.0021 17.8 0.2 0.0025 17.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Sugar_tr PF00083.19 KZN86619.1 - 1.8e-87 293.7 23.1 2.2e-87 293.5 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86619.1 - 2.8e-24 85.5 26.5 2.8e-24 85.5 18.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN86619.1 - 6.2e-07 28.0 4.4 6.2e-07 28.0 3.0 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 KZN86619.1 - 0.005 15.4 5.8 0.18 10.2 0.2 2.3 2 0 0 2 2 2 2 Reduced folate carrier DUF3021 PF11457.3 KZN86619.1 - 0.019 14.8 0.6 0.019 14.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) AAL_decarboxy PF03306.8 KZN86620.1 - 6.2e-66 221.5 0.4 7.5e-66 221.3 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 KZN86621.1 - 1e-51 174.8 0.1 2.2e-51 173.7 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KZN86621.1 - 2.1e-40 137.7 0.1 1.3e-38 132.0 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN86621.1 - 2e-31 108.5 0.1 5.2e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_32N PF00251.15 KZN86622.1 - 1.7e-44 152.4 0.5 7.1e-44 150.3 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN86622.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 KZN86622.1 - 0.0026 17.3 0.2 0.019 14.7 0.1 2.6 1 0 0 1 1 1 1 BNR/Asp-box repeat Nuc_deoxyrib_tr PF05014.10 KZN86623.1 - 0.026 14.3 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Ribosomal_L7Ae PF01248.21 KZN86624.1 - 4.4e-26 90.2 0.0 5.2e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KZN86624.1 - 0.0002 21.2 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Tim17 PF02466.14 KZN86625.1 - 7.4e-34 116.5 5.7 9e-34 116.2 3.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KZN86625.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal UPF0126 PF03458.8 KZN86625.1 - 5.7 6.6 7.3 13 5.5 0.6 3.1 3 1 1 4 4 4 0 UPF0126 domain zf-CCHC PF00098.18 KZN86626.1 - 0.00021 21.0 1.7 0.00085 19.1 0.2 2.2 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 KZN86626.1 - 0.0063 16.5 0.1 0.071 13.1 0.0 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein Trypsin PF00089.21 KZN86628.1 - 0.025 14.1 0.0 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Trypsin Peptidase_S7 PF00949.16 KZN86628.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Methyltransf_6 PF03737.10 KZN86629.1 - 7.9e-09 35.5 1.7 9.8e-09 35.2 1.2 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase FYRC PF05965.9 KZN86629.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus Ank_2 PF12796.2 KZN86631.1 - 4.7e-22 78.1 2.2 4.4e-10 39.7 0.0 4.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN86631.1 - 2.3e-19 69.3 7.9 9.7e-06 25.9 0.1 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN86631.1 - 2.5e-18 65.6 2.7 1.1e-08 34.9 0.0 5.8 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KZN86631.1 - 7.6e-17 60.2 4.5 0.0009 18.9 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 KZN86631.1 - 4.1e-14 51.2 7.4 0.039 14.1 0.0 7.5 8 1 1 9 9 9 4 Ankyrin repeat DUF3447 PF11929.3 KZN86631.1 - 0.029 14.1 0.3 0.71 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) CheD PF03975.8 KZN86631.1 - 0.11 12.2 0.2 2.9 7.7 0.0 2.4 1 1 1 2 2 2 0 CheD chemotactic sensory transduction Ank PF00023.25 KZN86632.1 - 5.4e-29 98.5 0.2 6.5e-06 25.6 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 KZN86632.1 - 7.8e-28 96.6 0.1 1.2e-13 51.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN86632.1 - 1.1e-20 71.6 0.3 0.00014 21.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KZN86632.1 - 7.1e-16 57.8 3.1 4.7e-08 33.0 0.1 3.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN86632.1 - 1.2e-12 47.9 1.1 0.001 19.5 0.0 4.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) CorA PF01544.13 KZN86633.1 - 6.2e-08 32.0 0.0 9.5e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.17 KZN86634.1 - 8.3e-73 245.4 0.0 1.1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bin3 PF06859.7 KZN86635.1 - 1.5e-26 92.5 0.0 2.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 KZN86635.1 - 4.7e-12 45.9 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN86635.1 - 5.1e-12 46.3 0.0 9.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN86635.1 - 9.7e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN86635.1 - 7.9e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN86635.1 - 2.8e-07 30.9 0.0 6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN86635.1 - 1.1e-06 28.6 0.1 3.6e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN86635.1 - 2.9e-05 23.5 0.0 8.9e-05 21.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KZN86635.1 - 4.5e-05 23.7 0.0 8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KZN86635.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KZN86635.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Glyco_hydro_16 PF00722.16 KZN86636.1 - 3e-12 46.2 0.0 1.8e-11 43.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SipA PF09052.5 KZN86636.1 - 2.7 6.2 6.7 3.5 5.9 4.6 1.0 1 0 0 1 1 1 0 Salmonella invasion protein A p450 PF00067.17 KZN86637.1 - 5.1e-67 226.3 0.0 6.8e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KZN86638.1 - 1.1e-11 44.1 0.0 1.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86638.1 - 1.2e-06 28.3 12.7 1.9e-06 27.6 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 KZN86638.1 - 0.11 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.17 KZN86639.1 - 2.5e-35 119.9 0.0 3.2e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86639.1 - 8.6e-30 102.5 0.0 7.7e-19 67.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86639.1 - 2.9e-11 43.0 0.0 1e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3445 PF11927.3 KZN86640.1 - 6.3e-76 255.0 0.7 7.7e-76 254.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Amidohydro_4 PF13147.1 KZN86641.1 - 2.2e-23 83.6 0.3 3.9e-23 82.8 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN86641.1 - 3.6e-23 82.7 0.0 3.2e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KZN86641.1 - 1.3e-08 34.4 0.2 3.1e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN86641.1 - 3.6e-07 29.7 0.0 0.00025 20.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family ubiquitin PF00240.18 KZN86641.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family AA_permease_2 PF13520.1 KZN86642.1 - 1.3e-36 126.1 48.6 1.6e-36 125.8 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN86642.1 - 1.3e-24 86.4 46.7 1.8e-24 85.9 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease Ribonuc_L-PSP PF01042.16 KZN86643.1 - 8.2e-20 70.7 0.0 9.7e-20 70.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.17 KZN86644.1 - 5.8e-176 585.3 0.1 6.5e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_11 PF13414.1 KZN86645.1 - 1.3e-24 85.5 4.9 2.2e-11 43.2 0.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 KZN86645.1 - 6e-22 75.7 3.1 1.6e-07 30.7 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86645.1 - 1.2e-21 75.3 2.8 2.5e-08 33.2 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86645.1 - 1.2e-16 59.6 4.5 8.2e-05 22.9 0.0 5.9 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86645.1 - 1.3e-16 60.7 2.9 2.4e-06 28.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN86645.1 - 3.6e-14 51.6 3.8 0.0012 18.8 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86645.1 - 1.2e-13 51.1 2.4 0.00058 20.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86645.1 - 2.3e-12 46.6 5.2 6.4e-08 32.4 0.5 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86645.1 - 9e-11 40.7 1.5 0.001 18.6 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86645.1 - 3.2e-10 39.0 0.4 0.00039 19.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 KZN86645.1 - 9.1e-10 38.5 3.9 0.0037 17.3 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN86645.1 - 2.1e-07 30.6 5.1 0.002 17.9 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN86645.1 - 2.8e-06 27.3 2.3 4.8e-05 23.4 0.4 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KZN86645.1 - 7.8e-06 26.0 0.9 0.95 10.0 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 KZN86645.1 - 0.00019 21.1 0.0 0.094 12.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 KZN86645.1 - 0.00027 20.0 0.2 0.34 9.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KZN86645.1 - 0.01 15.7 2.0 0.48 10.4 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KZN86645.1 - 0.028 14.2 1.8 1.3 8.9 0.5 3.8 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 KZN86645.1 - 0.068 12.7 0.1 3 7.3 0.0 3.0 3 1 1 4 4 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF1641 PF07849.6 KZN86645.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) DUF4192 PF13830.1 KZN86645.1 - 2.2 7.8 8.4 6.8 6.2 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) Amidase PF01425.16 KZN86646.1 - 2.4e-80 270.5 0.0 3.3e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Amidase LIP PF03583.9 KZN86647.1 - 5.2e-13 48.8 0.5 1.4e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.2 KZN86647.1 - 6.2e-10 39.3 3.4 9.8e-10 38.6 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN86647.1 - 7.1e-10 38.8 1.0 1.3e-09 37.9 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN86647.1 - 0.028 13.6 0.5 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.13 KZN86648.1 - 4.5e-07 29.6 10.2 1.1e-06 28.3 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL92 PF03048.9 KZN86648.1 - 0.14 11.7 2.1 0.27 10.8 1.4 1.4 1 0 0 1 1 1 0 UL92 family Abhydrolase_2 PF02230.11 KZN86649.1 - 0.00032 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KZN86649.1 - 0.00066 19.1 0.1 0.0015 17.9 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KZN86649.1 - 0.0048 16.1 0.1 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KZN86649.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN86649.1 - 0.085 12.0 0.1 0.25 10.5 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.9 KZN86650.1 - 6.8e-45 153.5 0.1 8.9e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 KZN86651.1 - 2.4e-43 148.1 31.0 2.4e-43 148.1 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN86651.1 - 8.9e-07 27.4 3.4 8.9e-07 27.4 2.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Transgly_assoc PF04226.8 KZN86651.1 - 0.021 14.9 7.8 0.021 14.9 5.4 3.6 3 0 0 3 3 3 0 Transglycosylase associated protein MFS_3 PF05977.8 KZN86651.1 - 1.8 6.5 9.7 0.26 9.3 3.8 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Lactamase_B_2 PF12706.2 KZN86652.1 - 3.6e-27 95.1 0.0 4.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN86652.1 - 4.2e-11 42.8 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 KZN86653.1 - 8.3e-10 38.1 8.4 0.0001 21.9 0.5 5.3 5 1 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 KZN86653.1 - 1.1e-09 37.4 9.9 0.011 15.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86653.1 - 5.7e-07 28.8 1.6 0.35 10.5 0.0 5.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86653.1 - 1.9e-06 27.7 6.7 0.053 13.4 0.0 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86653.1 - 2e-05 24.8 0.5 0.37 11.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86653.1 - 4.8e-05 22.8 1.6 0.26 11.1 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86653.1 - 9.4e-05 21.9 0.0 11 6.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86653.1 - 0.00024 21.4 6.1 14 6.6 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN86653.1 - 0.00036 20.7 6.0 0.11 12.9 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KZN86653.1 - 0.0068 16.3 3.5 0.93 9.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86653.1 - 0.025 15.2 19.2 1.1 10.0 0.1 6.4 5 1 1 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KZN86653.1 - 0.072 12.9 0.4 1.6 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 KZN86654.1 - 2.2e-23 82.8 0.0 2.7e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN86654.1 - 7.7e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FA_hydroxylase PF04116.8 KZN86655.1 - 1.2e-05 25.6 13.7 1.2e-05 25.6 9.5 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily DUF3669 PF12417.3 KZN86656.1 - 2.2e-22 78.5 0.0 4.7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein DUF4332 PF14229.1 KZN86656.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Methyltransf_28 PF02636.12 KZN86659.1 - 2.6e-36 125.2 0.0 3.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.5 KZN86659.1 - 0.12 12.1 0.4 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PRT_C PF08372.5 KZN86659.1 - 0.78 9.2 3.8 0.34 10.3 0.5 2.0 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal PALP PF00291.20 KZN86660.1 - 3.1e-51 174.4 0.2 3.8e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 KZN86661.1 - 3.3e-22 77.7 0.0 6e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Med3 PF11593.3 KZN86661.1 - 6.8 5.8 6.9 2.5 7.2 2.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal APG6 PF04111.7 KZN86662.1 - 3.4e-126 420.5 0.0 4.5e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 KZN86662.1 - 0.033 13.8 5.0 0.06 12.9 3.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 HoxA13_N PF12284.3 KZN86662.1 - 2.1 8.5 7.7 0.16 12.1 1.4 2.0 2 0 0 2 2 2 0 Hox protein A13 N terminal Clr5 PF14420.1 KZN86663.1 - 1.4e-18 66.4 4.3 2.5e-18 65.6 3.0 1.4 1 0 0 1 1 1 1 Clr5 domain Peroxin-13_N PF04088.8 KZN86664.1 - 5.3e-58 195.4 0.0 9.4e-58 194.6 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KZN86664.1 - 4.9e-10 38.7 0.0 1.2e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KZN86664.1 - 8.9e-09 34.6 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN86664.1 - 8.9e-07 28.3 0.1 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain OAD_gamma PF04277.8 KZN86664.1 - 0.07 13.5 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ERO1 PF04137.10 KZN86665.1 - 2.4e-136 454.4 0.0 2.9e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) p450 PF00067.17 KZN86667.1 - 9.7e-38 129.8 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RtcR PF06956.6 KZN86667.1 - 0.052 12.8 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase polyprenyl_synt PF00348.12 KZN86668.1 - 4e-35 120.9 0.0 6.9e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KZN86668.1 - 4.6e-05 22.7 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Abhydrolase_6 PF12697.2 KZN86669.1 - 1.5e-25 90.3 2.9 1.8e-25 90.1 2.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN86669.1 - 8.3e-08 32.1 0.6 1.3e-07 31.5 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN86669.1 - 0.13 11.7 0.1 2.7 7.5 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.23 KZN86670.1 - 6.3e-88 294.9 0.0 7.4e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN86670.1 - 2.5e-11 44.3 0.1 6.5e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 KZN86671.1 - 1.1e-125 419.7 20.3 1.3e-125 419.5 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86671.1 - 2.5e-23 82.3 25.2 2.5e-23 82.3 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.16 KZN86671.1 - 0.47 9.5 9.3 0.71 8.9 0.3 3.1 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.11 KZN86672.1 - 6.6e-31 107.3 36.9 1.5e-30 106.1 25.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 KZN86672.1 - 1.4 7.4 0.0 1.4 7.4 0.0 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Fungal_trans_2 PF11951.3 KZN86673.1 - 1.1e-05 24.1 6.2 7.3e-05 21.5 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain COesterase PF00135.23 KZN86674.1 - 3.3e-77 260.4 0.0 4.4e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN86674.1 - 7.8e-08 32.1 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN86674.1 - 0.049 13.3 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.23 KZN86677.1 - 3.4e-31 108.0 0.3 1.5e-30 105.9 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme CcmD PF04995.9 KZN86678.1 - 0.14 11.9 0.7 0.53 10.0 0.5 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Fungal_trans PF04082.13 KZN86679.1 - 1.4e-15 56.9 0.2 2.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KZN86680.1 - 3.2e-56 190.7 0.0 3.7e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN86680.1 - 0.015 15.0 0.4 0.024 14.3 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KZN86680.1 - 0.021 13.9 1.6 0.035 13.1 1.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KZN86680.1 - 0.049 12.4 0.2 0.089 11.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KZN86680.1 - 0.15 10.5 3.3 3.4 6.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KZN86680.1 - 0.5 10.2 5.9 10 5.9 3.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ALS2CR8 PF15299.1 KZN86682.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Pkinase PF00069.20 KZN86683.1 - 4e-31 108.1 0.0 8.2e-31 107.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86683.1 - 2.5e-10 39.8 0.0 5.2e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase MFS_1 PF07690.11 KZN86684.1 - 9.9e-39 133.0 29.5 9.9e-39 133.0 20.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN86684.1 - 2.6e-12 46.0 10.2 2.6e-12 46.0 7.1 2.4 2 2 1 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.4 KZN86684.1 - 0.036 13.2 0.2 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Methyltransf_23 PF13489.1 KZN86687.1 - 3e-15 56.3 0.1 3.9e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN86687.1 - 1.7e-14 53.7 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN86687.1 - 5.5e-12 46.0 0.0 9.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN86687.1 - 2.9e-11 43.6 0.0 6.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN86687.1 - 3.6e-09 36.9 0.0 8.5e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN86687.1 - 1.4e-08 35.3 0.0 2.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN86687.1 - 1.5e-06 27.4 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KZN86687.1 - 1.4e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN86687.1 - 0.00062 19.1 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KZN86687.1 - 0.003 16.4 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_15 PF09445.5 KZN86687.1 - 0.0038 16.8 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.6 KZN86687.1 - 0.01 14.5 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.13 KZN86687.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TPMT PF05724.6 KZN86687.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Beta-lactamase PF00144.19 KZN86688.1 - 1.4e-51 175.4 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KZN86688.1 - 4.4e-14 52.1 0.0 8.4e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Abhydrolase_5 PF12695.2 KZN86688.1 - 3.1e-10 39.9 0.3 6.1e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KZN86688.1 - 2e-07 29.6 0.0 0.0015 16.9 0.0 2.5 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KZN86688.1 - 5.4e-06 26.4 0.6 1.2e-05 25.3 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KZN86688.1 - 0.00056 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2413 PF10310.4 KZN86688.1 - 0.016 14.0 1.0 0.023 13.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DNA_pol3_beta PF00712.14 KZN86688.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain ABC_tran PF00005.22 KZN86689.1 - 1.5e-21 77.1 0.0 2.1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.12 KZN86689.1 - 0.054 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_16 PF13191.1 KZN86689.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MSA-2c PF12238.3 KZN86690.1 - 0.13 11.9 9.0 0.17 11.4 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ndc1_Nup PF09531.5 KZN86690.1 - 0.15 10.4 0.8 0.2 10.0 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MitoNEET_N PF10660.4 KZN86691.1 - 0.085 12.7 0.2 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF1814 PF08843.6 KZN86692.1 - 0.0016 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 KZN86692.1 - 0.0039 16.6 0.0 0.0093 15.4 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) NTP_transf_5 PF14907.1 KZN86692.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised nucleotidyltransferase Terpene_synth_C PF03936.11 KZN86693.1 - 7.4e-07 28.6 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain F-box-like PF12937.2 KZN86694.1 - 0.00027 20.5 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN86694.1 - 0.072 12.7 0.2 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 F-box domain DUF3659 PF12396.3 KZN86695.1 - 5e-187 605.8 85.6 1.5e-23 82.2 3.4 9.6 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) RPW8 PF05659.6 KZN86695.1 - 0.13 11.7 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Prominin PF05478.6 KZN86695.1 - 2 5.8 0.9 3.8 4.9 0.6 1.4 1 0 0 1 1 1 0 Prominin CDP-OH_P_transf PF01066.16 KZN86696.1 - 4.8e-16 58.9 2.8 4.8e-16 58.9 2.0 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1 PF01433.15 KZN86697.1 - 5.5e-05 22.4 0.0 0.79 8.7 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 LSM PF01423.17 KZN86698.1 - 3.4e-19 68.1 0.1 3.9e-19 67.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 KZN86699.1 - 3.2e-77 259.1 13.5 4.4e-77 258.7 9.4 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 MCR_C PF04609.7 KZN86699.1 - 0.071 11.8 0.1 0.19 10.4 0.1 1.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Myb_DNA-bind_4 PF13837.1 KZN86700.1 - 0.63 10.2 2.6 0.33 11.0 0.3 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain 2-Hacid_dh_C PF02826.14 KZN86701.1 - 5.8e-41 139.5 0.5 8e-41 139.1 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN86701.1 - 1.7e-09 37.2 0.0 2.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.19 KZN86701.1 - 0.046 13.6 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN86701.1 - 0.073 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ATP_transf PF09830.4 KZN86704.1 - 1e-22 79.6 0.3 2.1e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase zf-C2H2 PF00096.21 KZN86705.1 - 0.0067 16.7 25.0 0.91 10.0 0.1 5.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN86705.1 - 0.0067 16.6 20.9 0.11 12.8 0.0 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KZN86705.1 - 0.0088 15.9 0.8 0.2 11.6 0.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger Glyco_hydro_20 PF00728.17 KZN86706.1 - 5.9e-94 315.1 2.8 7.4e-94 314.7 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KZN86706.1 - 1.9e-19 70.5 0.0 3.8e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KZN86706.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DHDPS PF00701.17 KZN86707.1 - 1.3e-53 181.4 0.0 1.6e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SAS4 PF15460.1 KZN86708.1 - 3.8e-32 110.1 7.9 8.7e-32 109.0 5.5 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 KZN86708.1 - 0.029 14.8 0.5 0.029 14.8 0.3 4.6 4 2 0 5 5 5 0 PEHE domain APH PF01636.18 KZN86712.1 - 4.4e-05 23.3 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF3807 PF12720.2 KZN86713.1 - 7.3e-43 146.6 4.1 8.5e-43 146.4 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) VGLL4 PF15245.1 KZN86713.1 - 0.067 13.0 4.2 0.091 12.5 2.9 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 HVSL PF09749.4 KZN86714.1 - 5.1e-80 267.9 0.0 6e-80 267.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.20 KZN86715.1 - 4.2e-67 226.0 0.0 4.8e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86715.1 - 1.5e-30 106.1 0.0 2e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86715.1 - 6.2e-05 22.0 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN86715.1 - 0.0093 15.7 0.1 0.026 14.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN86715.1 - 0.041 12.7 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KZN86715.1 - 0.088 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pal1 PF08316.6 KZN86716.1 - 1.2e-09 38.7 0.1 2.4e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein Peptidase_S10 PF00450.17 KZN86717.1 - 7.6e-91 305.3 0.2 1.1e-90 304.7 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3425 PF11905.3 KZN86718.1 - 1.1e-26 93.3 1.9 1.5e-26 92.9 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Ferritin_2 PF13668.1 KZN86719.1 - 3.5e-09 36.7 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_3 PF00933.16 KZN86720.1 - 5.1e-91 304.7 0.0 7.7e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN86720.1 - 3.9e-62 209.7 0.5 6.8e-62 208.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN86720.1 - 1.6e-28 98.4 0.2 3.7e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SnAC PF14619.1 KZN86721.1 - 0.041 14.0 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex NAD_binding_10 PF13460.1 KZN86722.1 - 1.9e-06 28.0 0.0 4.8e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN86722.1 - 3.8e-05 23.0 0.0 0.00026 20.3 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family RRM_1 PF00076.17 KZN86723.1 - 1.6e-25 88.4 0.0 1.9e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86723.1 - 1.8e-18 66.2 0.0 2.1e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86723.1 - 1.2e-13 50.7 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN86723.1 - 0.007 16.2 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KZN86723.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1877 PF08974.5 KZN86723.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Limkain-b1 PF11608.3 KZN86723.1 - 0.11 12.2 0.1 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 Gelsolin PF00626.17 KZN86724.1 - 3e-38 129.3 0.6 4.5e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Sulfotransfer_3 PF13469.1 KZN86726.1 - 0.0003 21.7 0.3 0.00062 20.7 0.2 1.7 1 1 0 1 1 1 1 Sulfotransferase family Lipase_GDSL PF00657.17 KZN86727.1 - 2.4e-15 57.0 0.2 3.3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KZN86727.1 - 7e-14 52.3 0.1 9.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KZN86727.1 - 0.00065 19.4 0.1 0.0029 17.3 0.0 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family GspL_C PF12693.2 KZN86727.1 - 0.0035 17.1 0.1 0.067 12.9 0.0 2.3 2 0 0 2 2 2 1 GspL periplasmic domain ATP-grasp_2 PF08442.5 KZN86728.1 - 1.4e-41 142.0 0.0 2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KZN86728.1 - 1.1e-18 67.3 0.3 3.7e-18 65.5 0.3 1.8 2 0 0 2 2 2 1 CoA-ligase DUF303 PF03629.13 KZN86728.1 - 0.0081 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF303) Methyltransf_23 PF13489.1 KZN86729.1 - 3.9e-15 55.9 0.0 6.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN86729.1 - 1.6e-07 31.8 0.0 1.7e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN86729.1 - 0.0001 21.9 0.0 0.00059 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN86729.1 - 0.00023 21.5 0.0 0.0011 19.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN86729.1 - 0.00048 20.5 0.0 0.0072 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN86729.1 - 0.0021 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KZN86729.1 - 0.003 17.8 0.0 0.036 14.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN86729.1 - 0.021 14.8 0.0 0.072 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KZN86729.1 - 0.037 13.1 0.1 1.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KZN86729.1 - 0.05 12.6 0.0 0.71 8.9 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 KZN86729.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 KZN86729.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HlyIII PF03006.15 KZN86730.1 - 6.9e-35 120.4 15.2 8e-35 120.2 10.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related SnAC PF14619.1 KZN86730.1 - 0.048 13.8 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex PAS_9 PF13426.1 KZN86731.1 - 6.2e-22 77.9 0.0 1.2e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KZN86731.1 - 0.00062 19.7 0.0 1.8 8.6 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 KZN86731.1 - 0.0011 18.6 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 PAS fold AA_permease_2 PF13520.1 KZN86732.1 - 3.9e-54 183.8 54.3 4.7e-54 183.5 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN86732.1 - 5.2e-21 74.5 43.3 7e-21 74.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_4 PF13420.1 KZN86733.1 - 2.5e-07 30.7 0.0 0.0003 20.7 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain DUF2156 PF09924.4 KZN86735.1 - 9.5e-33 113.2 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) PX PF00787.19 KZN86736.1 - 6.8e-19 67.7 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 PX domain adh_short PF00106.20 KZN86738.1 - 5e-20 72.0 0.0 7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86738.1 - 4e-07 29.8 0.0 7.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN86738.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KZN86738.1 - 0.0019 17.4 0.0 0.0046 16.1 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KZN86738.1 - 0.029 14.3 0.1 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KZN86738.1 - 0.086 12.6 0.0 0.39 10.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RPN7 PF10602.4 KZN86739.1 - 2e-53 180.3 0.1 3.3e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KZN86739.1 - 1e-11 45.0 0.0 9.1e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 KZN86739.1 - 0.018 15.7 1.5 14 6.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 KZN86741.1 - 8.3e-21 74.3 0.0 1.4e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN86741.1 - 3.2e-08 33.9 0.0 5.7e-07 29.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN86741.1 - 6.1e-08 33.0 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN86741.1 - 1.8e-07 31.7 0.0 2.8e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN86741.1 - 0.00021 21.5 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN86741.1 - 0.00032 20.3 0.0 0.0041 16.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KZN86741.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KZN86741.1 - 0.081 12.2 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KZN86741.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KZN86741.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.17 KZN86742.1 - 7.4e-69 232.4 0.0 9e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KZN86743.1 - 1.4e-23 82.9 1.1 2.2e-23 82.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain KAR9 PF08580.5 KZN86744.1 - 1.4 7.1 9.3 1.6 6.8 6.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RAP1 PF07218.6 KZN86744.1 - 6.9 4.6 10.0 8.5 4.3 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 KZN86745.1 - 2.7e-22 78.9 33.1 1.1e-12 47.3 1.4 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KZN86745.1 - 5.5e-09 34.9 15.9 0.00035 19.1 2.8 3.2 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KZN86745.1 - 0.00055 19.6 0.2 1.1 9.0 0.1 2.9 2 0 0 2 2 2 2 MFS_1 like family Nucleoside_tran PF01733.13 KZN86745.1 - 0.0045 16.1 0.2 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 Nucleoside transporter zf-rbx1 PF12678.2 KZN86746.1 - 1.1e-11 44.6 0.4 2.4e-11 43.5 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KZN86746.1 - 9.8e-10 38.1 3.3 9.8e-10 38.1 2.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KZN86746.1 - 5e-07 29.2 0.5 1.4e-06 27.8 0.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN86746.1 - 9.9e-07 28.3 4.8 7e-06 25.6 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN86746.1 - 1.6e-05 24.8 2.1 1.6e-05 24.8 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN86746.1 - 3.5e-05 23.4 2.5 0.00011 21.8 0.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KZN86746.1 - 0.0021 17.8 1.7 0.037 13.8 0.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Kinesin-relat_1 PF12711.2 KZN86746.1 - 0.0089 16.4 0.5 0.026 14.9 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor zf-C3HC4_4 PF15227.1 KZN86746.1 - 0.025 14.4 1.3 0.052 13.4 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Transposase_28 PF04195.7 KZN86746.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon CopD PF05425.8 KZN86746.1 - 0.32 11.2 7.1 0.076 13.2 1.6 2.3 1 1 1 2 2 2 0 Copper resistance protein D zf-RING_UBOX PF13445.1 KZN86746.1 - 0.45 10.2 11.9 1.1 8.9 7.3 2.4 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KZN86746.1 - 2.9 7.5 5.1 0.63 9.6 1.2 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF3431 PF11913.3 KZN86747.1 - 5.3e-87 290.9 0.0 7.1e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) ASD2 PF08687.6 KZN86747.1 - 0.04 13.2 0.3 0.059 12.6 0.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Tim17 PF02466.14 KZN86749.1 - 5.1e-25 87.9 0.9 1e-24 87.0 0.7 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.13 KZN86750.1 - 2.6e-28 99.0 0.0 3.4e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_M14 PF00246.19 KZN86751.1 - 7.2e-20 71.7 0.1 1.2e-19 71.0 0.1 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 KZN86751.1 - 0.022 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 KZN86751.1 - 0.11 11.3 0.7 0.42 9.4 0.0 2.2 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.11 KZN86753.1 - 1.4e-35 122.7 19.0 1.4e-34 119.4 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.18 KZN86755.1 - 3.9e-74 249.5 40.3 2.7e-38 131.9 11.3 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN86755.1 - 5e-66 221.1 0.0 4.5e-33 114.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN86755.1 - 4.6e-13 48.9 2.4 6.4e-05 22.2 0.2 4.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN86755.1 - 9e-12 45.3 2.9 2.4e-08 34.1 0.1 3.2 4 0 0 4 4 3 2 AAA ATPase domain AAA_21 PF13304.1 KZN86755.1 - 1.2e-10 41.9 0.0 0.023 14.6 0.0 4.4 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN86755.1 - 7.9e-10 38.1 0.4 9.9e-05 21.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KZN86755.1 - 4e-09 35.8 0.0 0.0028 16.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN86755.1 - 6.2e-09 36.0 0.3 0.015 15.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KZN86755.1 - 1.1e-07 32.6 0.0 0.0072 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KZN86755.1 - 9.7e-07 27.7 0.4 0.029 12.9 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 KZN86755.1 - 1.8e-06 27.5 0.0 0.24 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KZN86755.1 - 1.2e-05 25.7 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KZN86755.1 - 1.4e-05 24.9 0.1 0.24 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KZN86755.1 - 4.6e-05 23.1 0.1 0.3 10.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KZN86755.1 - 4.8e-05 23.5 0.6 3.7 7.7 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KZN86755.1 - 7.8e-05 22.2 1.5 0.18 11.2 0.0 3.3 4 0 0 4 4 4 2 AAA-like domain MobB PF03205.9 KZN86755.1 - 8.4e-05 22.3 0.0 1.1 8.9 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KZN86755.1 - 0.00042 19.9 0.6 5 6.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 KZN86755.1 - 0.0005 19.7 0.0 0.059 13.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KZN86755.1 - 0.0022 18.3 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KZN86755.1 - 0.0031 17.5 0.1 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN86755.1 - 0.0034 17.5 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 KZN86755.1 - 0.0041 17.0 0.2 4.9 7.1 0.0 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 KZN86755.1 - 0.0051 16.4 0.0 3 7.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 KZN86755.1 - 0.0072 16.2 0.0 6.3 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.17 KZN86755.1 - 0.0087 14.9 0.0 1.9 7.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 KZN86755.1 - 0.012 15.2 0.1 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KZN86755.1 - 0.018 14.1 0.0 5.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KZN86755.1 - 0.023 14.1 0.4 12 5.3 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 KZN86755.1 - 0.03 13.8 0.0 1.8 7.9 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 KZN86755.1 - 0.032 12.9 0.0 1 7.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 KZN86755.1 - 0.037 13.5 0.1 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 KZN86755.1 - 0.042 13.2 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_PrkA PF08298.6 KZN86755.1 - 0.045 12.4 0.0 2.7 6.6 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain G-alpha PF00503.15 KZN86755.1 - 0.062 11.9 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.15 KZN86755.1 - 0.086 12.4 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.12 KZN86755.1 - 0.091 12.5 0.0 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 KZN86755.1 - 0.33 10.9 6.0 7.1 6.6 0.2 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit adh_short_C2 PF13561.1 KZN86756.1 - 5.5e-24 85.2 0.0 7.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN86756.1 - 6.5e-24 84.7 0.4 8.6e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN86756.1 - 2e-05 24.3 0.1 3.2e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 KR domain F_bP_aldolase PF01116.15 KZN86757.1 - 2.8e-76 256.3 0.1 3.1e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KZN86757.1 - 0.00085 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotriesterase family CobS PF02654.10 KZN86757.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Fungal_trans_2 PF11951.3 KZN86758.1 - 5.5e-19 68.0 4.4 3.6e-16 58.7 1.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86758.1 - 1.7e-08 34.2 9.6 3.1e-08 33.4 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN86758.1 - 4.1e-06 25.8 4.5 8.6e-06 24.8 2.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1281 PF06924.6 KZN86758.1 - 0.075 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) APH PF01636.18 KZN86760.1 - 9.2e-10 38.6 0.0 1.5e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN86760.1 - 3.6e-05 23.4 0.0 5.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase NAD_binding_4 PF07993.7 KZN86761.1 - 3.7e-43 147.2 0.0 1.2e-42 145.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KZN86761.1 - 2.3e-22 78.9 0.0 1.4e-17 63.2 0.0 2.9 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KZN86761.1 - 7.6e-13 48.4 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN86761.1 - 2.6e-08 34.0 0.0 2.5e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN86761.1 - 0.002 16.8 0.0 0.0089 14.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KZN86761.1 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KZN86761.1 - 0.033 14.0 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KZN86761.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 KR domain HTH_Tnp_1 PF01527.15 KZN86761.1 - 0.11 12.4 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Transposase p450 PF00067.17 KZN86762.1 - 7.1e-63 212.7 0.0 8.6e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 KZN86763.1 - 6.6e-21 75.1 0.0 8.9e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN86763.1 - 0.01 14.8 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Kdo PF06293.9 KZN86763.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KZN86764.1 - 3.6e-23 82.6 0.3 5.5e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN86764.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KZN86765.1 - 7.5e-31 107.1 31.4 1.6e-21 76.4 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN86765.1 - 3.3e-20 72.1 21.3 7.9e-20 70.8 14.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 KZN86766.1 - 2.9e-41 141.3 0.0 3.5e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN86766.1 - 1.1e-05 24.4 0.0 2.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KZN86766.1 - 4.1e-05 23.3 0.0 6.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN86766.1 - 0.00028 20.1 0.0 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KZN86766.1 - 0.00032 20.0 0.0 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 KZN86766.1 - 0.00039 20.1 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KZN86766.1 - 0.001 18.5 0.0 0.071 12.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 KZN86766.1 - 0.0015 17.9 0.0 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.2 KZN86766.1 - 0.008 15.0 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KZN86766.1 - 0.0097 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 KZN86766.1 - 0.0099 14.7 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 KZN86766.1 - 0.016 13.7 0.0 0.13 10.7 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 KZN86766.1 - 0.071 11.7 0.0 1.2 7.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2424) Esterase_phd PF10503.4 KZN86766.1 - 0.096 11.9 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase MFS_1 PF07690.11 KZN86767.1 - 4.3e-30 104.6 18.9 4.3e-30 104.6 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LamB_YcsF PF03746.11 KZN86768.1 - 3.7e-71 239.0 0.0 4.2e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AHS2 PF02626.10 KZN86770.1 - 1.9e-71 240.5 0.0 3e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KZN86770.1 - 5.6e-55 185.9 0.0 9.5e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KZN86770.1 - 7.9e-38 128.9 0.3 1.7e-37 127.8 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 KZN86770.1 - 2e-33 115.5 0.0 3.9e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 KZN86770.1 - 1.7e-32 111.5 0.0 3.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KZN86770.1 - 5.8e-12 45.7 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN86770.1 - 1.6e-09 36.9 0.0 3.1e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KZN86770.1 - 3.4e-09 36.2 2.2 1.1e-07 31.3 1.1 3.0 2 1 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KZN86770.1 - 7.4e-06 25.5 0.5 0.0012 18.5 0.1 2.7 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KZN86770.1 - 6e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 KZN86770.1 - 0.038 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KZN86770.1 - 0.091 11.9 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Glyco_hydro_31 PF01055.21 KZN86771.1 - 3.6e-158 527.0 2.3 4.6e-158 526.6 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 KZN86771.1 - 0.14 11.3 0.2 0.42 9.7 0.0 1.8 2 1 0 2 2 2 0 Rotavirus major outer capsid protein VP7 Aldose_epim PF01263.15 KZN86772.1 - 4.3e-48 163.9 0.4 6.3e-48 163.4 0.3 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase GMC_oxred_N PF00732.14 KZN86773.1 - 1.3e-75 254.3 0.0 1.7e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN86773.1 - 4.7e-25 88.5 0.0 8.9e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN86773.1 - 5.2e-05 22.3 0.1 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN86773.1 - 0.00041 19.3 0.0 0.0009 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KZN86773.1 - 0.00043 20.2 0.1 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN86773.1 - 0.0092 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KZN86773.1 - 0.014 14.5 0.1 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KZN86773.1 - 0.031 14.1 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactonase PF10282.4 KZN86774.1 - 4e-73 246.4 0.0 5.3e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 KZN86774.1 - 0.029 14.3 1.3 0.35 10.9 0.4 2.5 2 0 0 2 2 2 0 NHL repeat Fungal_trans_2 PF11951.3 KZN86776.1 - 2.4e-13 49.4 0.1 3.6e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86776.1 - 1.3e-05 25.0 6.3 2.7e-05 23.9 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apc3 PF12895.2 KZN86776.1 - 0.13 12.4 1.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.20 KZN86777.1 - 1.7e-22 79.8 0.0 2.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 KZN86777.1 - 1.1e-19 70.5 0.2 1.6e-07 31.5 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN86777.1 - 1.4e-12 47.4 1.0 0.00081 19.5 0.2 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KZN86777.1 - 2.2e-12 46.6 0.0 6.1e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 KZN86777.1 - 3.8e-12 45.3 3.3 2.6e-06 26.9 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 KZN86777.1 - 7.5e-11 41.1 0.1 0.0025 17.8 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 KZN86777.1 - 1.9e-08 34.5 0.3 0.00016 22.0 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Sugar_tr PF00083.19 KZN86778.1 - 2.5e-48 164.8 14.3 4.5e-47 160.6 9.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86778.1 - 2e-05 23.5 20.3 2e-05 23.5 14.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_US9 PF06072.6 KZN86778.1 - 5.3 6.9 7.5 2.1 8.2 0.2 3.3 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 CorA PF01544.13 KZN86780.1 - 1.1e-09 37.7 1.5 1.4e-09 37.4 1.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UPF0093 PF03653.8 KZN86780.1 - 0.0018 18.2 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) 7tm_7 PF08395.7 KZN86780.1 - 0.047 12.7 0.3 0.075 12.0 0.1 1.3 1 1 0 1 1 1 0 7tm Chemosensory receptor PgaD PF13994.1 KZN86780.1 - 0.068 12.6 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein NfeD PF01957.13 KZN86780.1 - 0.069 13.2 0.0 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding H_PPase PF03030.11 KZN86780.1 - 0.08 11.1 0.1 0.092 10.9 0.1 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF4064 PF13273.1 KZN86780.1 - 0.17 11.9 3.9 0.59 10.2 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Peptidase_M56 PF05569.6 KZN86780.1 - 0.36 9.7 2.8 1.6 7.6 0.6 1.9 1 1 1 2 2 2 0 BlaR1 peptidase M56 NVEALA PF14055.1 KZN86780.1 - 0.39 10.4 1.7 0.47 10.2 0.3 1.7 2 0 0 2 2 2 0 NVEALA protein DUF3980 PF13140.1 KZN86780.1 - 0.86 9.9 6.6 6.8 7.0 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3980) tRNA-synt_1 PF00133.17 KZN86781.1 - 4e-219 728.5 0.0 2.1e-218 726.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KZN86781.1 - 3.3e-32 111.3 1.5 1.1e-31 109.7 1.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KZN86781.1 - 2.1e-17 62.8 0.1 4.3e-08 32.2 0.0 4.9 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KZN86781.1 - 4.1e-07 29.4 5.9 4.1e-05 22.9 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KZN86781.1 - 0.002 18.1 6.6 0.002 18.1 4.6 2.8 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.20 KZN86782.1 - 7e-58 195.7 0.0 8.1e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86782.1 - 1.7e-18 66.6 0.0 2.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN86782.1 - 1.6e-07 31.3 0.5 9.1e-05 22.2 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN86782.1 - 0.0086 15.6 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KZN86782.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN86782.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aconitase_B_N PF11791.3 KZN86782.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Aconitate B N-terminal domain RNase_P_p30 PF01876.11 KZN86783.1 - 4.5e-50 168.7 0.0 6e-50 168.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Ureidogly_hydro PF04115.7 KZN86784.1 - 4e-53 179.1 0.0 4.8e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MutS_V PF00488.16 KZN86785.1 - 4.8e-84 281.4 0.0 7.2e-84 280.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN86785.1 - 1.4e-39 136.0 0.0 5e-39 134.1 0.0 2.0 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KZN86785.1 - 9.4e-21 73.9 0.0 2.4e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KZN86785.1 - 7.9e-07 29.2 0.0 2.4e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II CCDC92 PF14916.1 KZN86785.1 - 0.02 14.5 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_29 PF13555.1 KZN86785.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.13 KZN86785.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.1 KZN86785.1 - 0.095 13.0 0.1 0.43 10.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KZN86785.1 - 0.14 12.0 0.0 0.6 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Sec63 PF02889.11 KZN86786.1 - 2.6e-198 657.6 0.1 5e-108 361.0 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KZN86786.1 - 2.5e-55 186.5 0.8 6.3e-31 107.1 0.0 4.0 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KZN86786.1 - 1.7e-15 57.2 0.0 3.5e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KZN86786.1 - 9.4e-10 38.2 0.0 1.6e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KZN86786.1 - 0.0001 22.4 2.3 0.028 14.5 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KZN86786.1 - 0.0002 20.8 0.0 2.4 7.5 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain T2SE PF00437.15 KZN86786.1 - 0.0003 19.7 0.0 0.7 8.7 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.11 KZN86786.1 - 0.00054 19.2 0.0 0.09 11.9 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KZN86786.1 - 0.0043 16.7 0.0 0.84 9.4 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KZN86786.1 - 0.0072 15.8 0.0 0.062 12.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Peptidase_S9 PF00326.16 KZN86787.1 - 3.6e-49 166.8 0.1 6.9e-49 165.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN86787.1 - 7.2e-08 32.3 0.1 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN86787.1 - 2.7e-06 27.4 1.2 8.1e-06 25.8 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KZN86787.1 - 0.0052 15.3 0.1 0.057 11.8 0.1 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Glyco_hydro_43 PF04616.9 KZN86788.1 - 2.9e-27 95.4 1.3 9.1e-17 61.0 0.3 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 MFS_1 PF07690.11 KZN86789.1 - 1.3e-23 83.2 37.3 1.9e-21 76.1 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2374 PF09574.5 KZN86789.1 - 0.46 10.1 5.0 3.1 7.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) adh_short PF00106.20 KZN86790.1 - 1.3e-06 28.4 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN86790.1 - 0.00044 20.0 0.0 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN86790.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 KZN86791.1 - 7.9e-38 130.0 0.0 1e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86791.1 - 6.2e-13 48.4 0.0 6.7e-06 25.3 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KZN86791.1 - 0.0032 16.4 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KZN86791.1 - 0.0082 15.8 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family CAP_GLY PF01302.20 KZN86792.1 - 3.6e-16 58.6 0.6 7.1e-16 57.6 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 KZN86792.1 - 0.00014 21.5 32.8 0.00072 19.2 5.7 3.3 1 1 2 3 3 3 2 IncA protein SlyX PF04102.7 KZN86792.1 - 0.00073 19.8 23.7 0.14 12.5 4.7 3.9 3 0 0 3 3 3 2 SlyX TMF_DNA_bd PF12329.3 KZN86792.1 - 0.019 14.7 29.1 0.79 9.5 1.4 4.9 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KZN86792.1 - 0.025 13.7 6.4 1.5 7.9 0.1 3.0 1 1 3 4 4 4 0 Reovirus sigma C capsid protein PilJ PF13675.1 KZN86792.1 - 0.033 14.5 19.4 0.45 10.8 1.3 3.5 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3552 PF12072.3 KZN86792.1 - 0.036 13.2 35.0 0.082 12.1 2.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3552) AAA_13 PF13166.1 KZN86792.1 - 0.059 11.8 19.5 0.047 12.1 8.4 2.3 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 KZN86792.1 - 0.075 11.6 26.8 0.077 11.6 2.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.8 KZN86792.1 - 0.092 12.6 22.2 0.19 11.6 1.3 3.5 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Cortex-I_coil PF09304.5 KZN86792.1 - 0.24 11.4 31.1 0.38 10.8 8.2 3.9 2 1 0 3 3 3 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KZN86792.1 - 0.34 11.1 10.9 4.8 7.4 1.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 KZN86792.1 - 0.34 11.6 10.4 2.1 9.0 1.6 3.3 3 0 0 3 3 3 0 Occludin homology domain FliJ PF02050.11 KZN86792.1 - 0.4 10.7 26.0 0.45 10.5 0.6 3.9 2 1 2 4 4 4 0 Flagellar FliJ protein EzrA PF06160.7 KZN86792.1 - 0.46 8.5 25.0 0.18 9.9 4.7 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Tropomyosin PF00261.15 KZN86792.1 - 0.66 9.0 37.2 0.062 12.3 14.2 2.9 1 1 2 3 3 3 0 Tropomyosin FliD_N PF02465.13 KZN86792.1 - 0.8 10.1 7.7 11 6.4 0.2 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.7 KZN86792.1 - 2.3 8.0 13.8 2.2 8.0 2.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 KZN86792.1 - 2.6 7.5 21.5 1.4 8.4 1.6 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 KZN86792.1 - 5.3 7.2 15.6 1.7 8.8 2.6 3.8 3 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KZN86792.1 - 6.8 6.4 30.3 4.5 7.0 7.5 3.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 KZN86792.1 - 8 6.3 37.9 2.4 8.0 1.7 4.1 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 KZN86792.1 - 8.2 6.1 14.1 14 5.4 1.9 3.4 2 1 0 3 3 3 0 Laminin Domain II 3-HAO PF06052.7 KZN86793.1 - 7e-56 187.8 0.0 8.3e-56 187.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KZN86793.1 - 0.00035 20.0 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KZN86793.1 - 0.00075 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin DZR PF12773.2 KZN86793.1 - 0.016 14.9 1.1 0.053 13.3 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon AraC_binding PF02311.14 KZN86793.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain RTC PF01137.16 KZN86794.1 - 1.8e-29 102.1 0.1 2.5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KZN86794.1 - 2.2e-29 101.4 0.0 3.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SLAC1 PF03595.12 KZN86795.1 - 2.2e-81 273.0 38.1 2.6e-81 272.8 26.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HSCB_C PF07743.8 KZN86797.1 - 1.1e-19 70.6 0.6 3.5e-19 69.0 0.1 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KZN86797.1 - 3.6e-10 39.4 0.0 7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 KZN86798.1 - 1e-42 142.5 24.7 2.1e-08 33.7 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KZN86798.1 - 2.6e-14 52.1 5.4 2.6e-14 52.1 3.8 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like SpoIIE PF07228.7 KZN86799.1 - 1.2e-10 41.4 0.2 5.4e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KZN86799.1 - 3e-09 36.5 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KZN86799.1 - 7.4e-06 25.5 0.0 0.084 12.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PWWP PF00855.12 KZN86800.1 - 6.2e-17 61.5 0.0 6.2e-17 61.5 0.0 2.6 2 1 0 2 2 2 1 PWWP domain PAP2_3 PF14378.1 KZN86801.1 - 4.8e-14 52.3 20.1 9.6e-12 44.8 5.7 3.9 3 1 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 KZN86801.1 - 0.00023 20.8 3.9 0.00094 18.8 2.4 2.1 1 1 1 2 2 2 1 PAP2 superfamily MFS_1 PF07690.11 KZN86801.1 - 0.0088 14.8 4.3 0.03 13.0 2.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PAP2_C PF14360.1 KZN86801.1 - 4.4 7.6 7.0 0.62 10.3 0.2 2.9 3 0 0 3 3 3 0 PAP2 superfamily C-terminal ComA PF02679.10 KZN86802.1 - 5.3e-81 271.2 0.0 6.3e-81 271.0 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Pro_Al_protease PF02983.9 KZN86802.1 - 0.034 14.0 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Fungal_trans PF04082.13 KZN86803.1 - 3.7e-14 52.2 0.0 6.9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SH3_1 PF00018.23 KZN86805.1 - 1.6e-34 117.0 6.2 3.6e-13 48.6 0.1 4.0 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KZN86805.1 - 8.8e-34 114.9 0.3 1.5e-33 114.2 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KZN86805.1 - 4.7e-32 109.3 7.1 3.4e-13 48.9 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KZN86805.1 - 6.2e-22 76.8 0.3 3.4e-08 32.8 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 KZN86805.1 - 2.3e-05 24.4 5.1 0.057 13.6 0.5 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain Glyco_tranf_2_3 PF13641.1 KZN86805.1 - 0.092 12.5 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF1720 PF08226.6 KZN86805.1 - 7 6.7 169.1 0.061 13.3 29.6 6.1 1 1 3 4 4 4 0 Domain of unknown function (DUF1720) PRKCSH PF07915.8 KZN86806.1 - 3.1e-19 69.5 0.4 3.1e-19 69.5 0.3 3.3 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KZN86806.1 - 0.00025 20.5 0.5 0.0024 17.3 0.3 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pirin PF02678.11 KZN86807.1 - 1.4e-32 111.7 0.1 2.7e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KZN86807.1 - 2.7e-24 85.2 0.0 1.3e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KZN86807.1 - 7.2e-07 28.6 0.5 0.00012 21.5 0.6 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KZN86807.1 - 0.042 13.2 0.2 0.42 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF861) LRR_6 PF13516.1 KZN86808.1 - 0.024 14.6 7.4 25 5.3 0.0 6.4 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 KZN86808.1 - 0.55 9.9 8.5 39 4.0 1.3 5.1 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.18 KZN86809.1 - 9e-63 211.8 0.3 1.5e-62 211.1 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN86809.1 - 2.7e-12 46.3 0.0 7.6e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KZN86809.1 - 1.5e-05 24.5 12.1 1.5e-05 24.5 8.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 KZN86809.1 - 1.6e-05 24.4 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 KZN86809.1 - 0.00073 19.5 11.2 0.00073 19.5 7.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN86809.1 - 0.0013 18.4 10.9 0.0013 18.4 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN86809.1 - 0.0021 17.8 12.1 0.0021 17.8 8.4 2.3 2 0 0 2 2 2 1 Ring finger domain Zn_Tnp_IS91 PF14319.1 KZN86809.1 - 0.0054 16.2 3.5 0.0054 16.2 2.4 2.5 2 0 0 2 2 2 1 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 KZN86809.1 - 0.16 11.7 5.6 0.48 10.1 3.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger C2 PF00168.25 KZN86810.1 - 1.8e-08 34.1 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 KZN86811.1 - 7.9e-35 119.1 0.1 7.9e-35 119.1 0.1 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 KZN86811.1 - 7.6e-13 48.5 0.2 2.6e-12 46.8 0.1 1.9 1 0 0 1 1 1 1 PH domain YTH PF04146.10 KZN86812.1 - 4.8e-57 191.4 0.0 6.9e-57 190.9 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KZN86812.1 - 3.1e-08 33.1 0.0 5.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86812.1 - 5.7e-07 29.4 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86812.1 - 0.011 15.5 0.1 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KZN86814.1 - 8.8e-141 469.5 27.4 1.1e-140 469.2 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN86814.1 - 8.1e-26 90.5 48.8 1.1e-20 73.6 17.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN86814.1 - 3.8e-05 22.2 28.7 0.00021 19.8 1.9 3.0 2 1 0 3 3 3 2 MFS/sugar transport protein Pox_A14 PF05767.7 KZN86814.1 - 0.0052 16.7 0.3 0.3 11.0 0.0 3.0 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 PI3_PI4_kinase PF00454.22 KZN86815.1 - 3.2e-35 121.6 0.0 2.7e-34 118.6 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KZN86815.1 - 1.6e-23 82.8 0.0 3.6e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 KZN86815.1 - 0.13 11.2 0.0 0.35 9.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.20 KZN86816.1 - 7.1e-77 258.0 0.0 9.7e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86816.1 - 1.6e-36 125.6 0.0 2.3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KZN86816.1 - 1.3e-13 50.8 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KZN86816.1 - 2.5e-11 43.0 0.0 1.6e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN86816.1 - 2.2e-05 24.3 0.1 4.6e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KZN86816.1 - 0.054 12.8 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KZN86816.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KZN86816.1 - 0.094 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KZN86816.1 - 0.13 11.5 0.1 1.7 7.9 0.0 2.1 1 1 1 2 2 2 0 RIO1 family p450 PF00067.17 KZN86817.1 - 1.1e-75 255.0 0.0 1.4e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.5 KZN86818.1 - 1.4e-21 76.1 0.1 2.2e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 KZN86819.1 - 1.3e-62 211.2 0.0 1.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86819.1 - 1.6e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86819.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN86819.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.18 KZN86820.1 - 4.6e-97 324.7 0.0 9.4e-97 323.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Med9 PF07544.8 KZN86820.1 - 0.016 14.9 2.9 0.017 14.8 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KZN86820.1 - 3.9 7.0 9.4 13 5.3 0.2 2.5 2 0 0 2 2 2 0 IncA protein DAGAT PF03982.8 KZN86821.1 - 2.4e-90 302.2 0.0 3e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 KZN86821.1 - 3 7.4 7.0 2.1 7.8 3.6 1.6 1 1 1 2 2 2 0 Rer1 family G-patch PF01585.18 KZN86822.1 - 5e-06 26.1 0.1 8.9e-05 22.1 0.1 2.5 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.7 KZN86822.1 - 0.0064 15.4 21.3 0.0069 15.3 14.7 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) Macoilin PF09726.4 KZN86822.1 - 0.32 9.2 21.5 0.37 9.0 14.9 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 KZN86822.1 - 0.46 8.7 40.4 0.59 8.4 28.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FLO_LFY PF01698.11 KZN86822.1 - 2 7.2 17.4 2.9 6.6 12.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Asp-B-Hydro_N PF05279.6 KZN86822.1 - 2.9 7.6 19.7 4 7.2 13.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 KZN86822.1 - 3.4 6.0 42.9 4.6 5.5 29.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Peptidase_S64 PF08192.6 KZN86822.1 - 8.4 4.5 16.8 9.9 4.3 11.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Syja_N PF02383.13 KZN86823.1 - 1.1e-81 274.0 0.0 1.5e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KZN86823.1 - 8.4e-25 88.1 0.8 1.5e-24 87.3 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RAMP4 PF06624.7 KZN86824.1 - 8.3e-08 31.6 0.0 9.2e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.15 KZN86825.1 - 1.3e-84 284.4 0.1 2e-79 267.3 0.1 2.0 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 KZN86825.1 - 9.6e-07 29.0 3.5 0.057 13.6 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KZN86825.1 - 3.9e-05 23.3 4.0 0.062 13.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 KZN86825.1 - 0.00088 19.1 1.7 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KZN86825.1 - 0.42 11.1 5.3 9.9 6.7 0.1 4.6 3 2 2 5 5 5 0 HEAT-like repeat TPR_11 PF13414.1 KZN86826.1 - 7.1e-11 41.5 0.6 8.1e-07 28.6 0.1 4.1 2 1 3 5 5 5 3 TPR repeat TPR_14 PF13428.1 KZN86826.1 - 1.9e-08 34.1 0.3 0.0041 17.6 0.1 4.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86826.1 - 2.9e-07 30.7 0.4 0.00083 19.6 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN86826.1 - 6.8e-07 28.9 0.0 0.064 13.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86826.1 - 8.4e-06 25.1 0.0 0.00021 20.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN86826.1 - 1.2e-05 24.8 0.2 0.0029 17.3 0.1 4.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86826.1 - 5.1e-05 23.8 0.0 0.66 10.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86826.1 - 0.0057 16.3 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86826.1 - 0.017 15.0 4.7 0.23 11.4 0.1 3.7 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN86826.1 - 0.52 10.2 5.1 0.74 9.7 0.0 3.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.6 KZN86827.1 - 1.8 8.3 14.3 2.9 7.6 9.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Menin PF05053.8 KZN86827.1 - 9.3 4.2 8.9 16 3.4 6.2 1.3 1 0 0 1 1 1 0 Menin Yae1_N PF09811.4 KZN86828.1 - 1.2e-07 31.1 49.9 4.5 6.8 0.1 9.7 4 2 1 5 5 5 1 Essential protein Yae1, N terminal MspA PF09203.6 KZN86828.1 - 8.7e-05 22.0 1.2 0.49 9.8 0.3 3.0 1 1 1 2 2 2 2 MspA Retrotrans_gag PF03732.12 KZN86829.1 - 2.5e-11 43.5 1.0 1.9e-10 40.6 0.0 2.5 3 1 1 4 4 4 1 Retrotransposon gag protein PNMA PF14893.1 KZN86829.1 - 0.054 12.5 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 PNMA Baculo_PEP_C PF04513.7 KZN86829.1 - 0.2 11.4 1.8 2.4 7.9 0.2 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YccV-like PF08755.6 KZN86831.1 - 8.5e-26 89.8 0.0 1.5e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KZN86831.1 - 2.1e-10 40.2 0.0 5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KZN86831.1 - 9.5e-06 25.2 1.2 2.3e-05 24.0 0.8 1.7 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.26 KZN86832.1 - 2.8e-25 87.8 2.0 2.9e-25 87.7 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KZN86832.1 - 3.1e-09 36.7 6.8 3.1e-09 36.7 4.7 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN86832.1 - 5.3e-07 29.6 5.0 5.3e-07 29.6 3.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KZN86832.1 - 5.1e-06 26.5 5.4 0.012 15.7 1.9 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KZN86832.1 - 1e-05 25.5 9.2 0.014 15.6 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type LIM PF00412.17 KZN86832.1 - 0.067 13.2 2.6 8.6 6.5 0.0 2.5 2 0 0 2 2 2 0 LIM domain DUF2387 PF09526.5 KZN86832.1 - 0.09 12.7 1.1 0.36 10.7 0.7 2.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Cytochrome_C554 PF13435.1 KZN86832.1 - 0.27 11.2 7.3 0.25 11.3 2.3 2.5 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-C2H2_4 PF13894.1 KZN86832.1 - 0.29 11.5 8.5 1.9 9.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Elf1 PF05129.8 KZN86832.1 - 0.41 10.3 3.4 0.61 9.8 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Cytochrom_NNT PF03264.9 KZN86832.1 - 0.74 9.2 8.6 0.34 10.3 3.9 1.9 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region zf-C2H2_6 PF13912.1 KZN86832.1 - 3.8 7.5 8.3 17 5.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger R3H PF01424.17 KZN86833.1 - 1.3e-13 50.4 0.1 2.5e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KZN86833.1 - 1.1e-10 41.1 0.2 2.2e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KZN86833.1 - 0.00028 20.6 0.2 0.00096 18.9 0.2 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site TIP_N PF12457.3 KZN86833.1 - 0.0044 17.0 0.7 0.02 14.9 0.5 2.1 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal Peptidase_C54 PF03416.14 KZN86834.1 - 2.1e-48 164.8 0.0 4.9e-40 137.4 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Histone PF00125.19 KZN86835.1 - 2.9e-22 78.5 0.3 4.2e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN86835.1 - 0.00023 21.1 1.1 0.0004 20.3 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KZN86835.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 KZN86835.1 - 0.02 14.3 0.1 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 KZN86836.1 - 8.2e-26 89.9 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN86836.1 - 1.2e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 KZN86837.1 - 2.7e-09 36.6 0.5 4e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN86837.1 - 2.2e-06 27.7 0.3 3.2e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 KZN86838.1 - 3.5e-79 265.3 0.0 4.7e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KZN86838.1 - 1.6e-18 66.0 1.5 3e-18 65.2 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Tape_meas_lam_C PF09718.5 KZN86838.1 - 0.012 15.5 0.0 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Ribosomal_60s PF00428.14 KZN86838.1 - 0.022 15.1 2.3 0.022 15.1 1.6 2.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein Biotin_lipoyl_2 PF13533.1 KZN86838.1 - 0.022 14.3 0.4 0.86 9.3 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.1 KZN86838.1 - 0.027 14.1 0.2 0.34 10.6 0.0 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 KZN86838.1 - 0.044 13.4 0.5 0.099 12.3 0.3 1.7 1 1 0 1 1 1 0 Glycine cleavage H-protein DUF2360 PF10152.4 KZN86838.1 - 2.8 8.2 8.5 4.9 7.4 5.9 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PCMT PF01135.14 KZN86840.1 - 2.8e-63 213.2 0.0 3.8e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KZN86840.1 - 2.3e-10 41.0 0.0 3.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN86840.1 - 9.6e-09 34.9 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KZN86840.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN86840.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN86840.1 - 3.8e-05 23.9 0.0 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN86840.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KZN86840.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 KZN86840.1 - 0.0017 18.8 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN86840.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KZN86840.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KZN86840.1 - 0.025 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 KZN86840.1 - 0.038 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 KZN86840.1 - 0.051 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KZN86840.1 - 0.063 12.3 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KZN86840.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 KZN86840.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DnaJ PF00226.26 KZN86841.1 - 3.6e-24 84.2 1.0 3.6e-24 84.2 0.7 3.0 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KZN86841.1 - 5.4e-19 67.6 8.2 9.5e-07 28.3 0.0 5.3 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KZN86841.1 - 3.3e-18 64.0 0.7 0.08 12.9 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KZN86841.1 - 6.5e-18 63.5 0.0 0.00043 19.7 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN86841.1 - 1.8e-11 43.5 13.3 0.056 14.1 0.0 7.8 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86841.1 - 2.5e-10 40.7 16.8 0.0022 18.6 0.5 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86841.1 - 3.2e-10 39.0 0.1 0.14 11.9 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN86841.1 - 4.4e-10 39.7 9.2 0.0012 19.1 1.5 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN86841.1 - 1.2e-09 37.8 11.3 0.00054 19.7 0.2 4.9 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 KZN86841.1 - 4.1e-08 33.1 2.3 42 4.8 0.0 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86841.1 - 1.2e-06 28.3 9.2 0.8 9.6 0.0 6.3 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN86841.1 - 1.2e-05 25.1 3.3 0.23 11.7 0.0 6.6 7 1 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN86841.1 - 0.0008 19.4 9.2 0.85 9.8 0.2 4.8 4 2 3 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 RPT PF13446.1 KZN86841.1 - 0.0038 16.5 0.0 0.15 11.5 0.0 3.3 4 0 0 4 4 4 1 A repeated domain in UCH-protein YfiO PF13525.1 KZN86841.1 - 0.026 14.0 3.5 0.1 12.0 0.3 3.0 2 2 0 2 2 2 0 Outer membrane lipoprotein DUF2786 PF10979.3 KZN86841.1 - 3.4 7.4 10.4 0.59 9.8 0.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2786) RF-1 PF00472.15 KZN86842.1 - 7.7e-33 112.6 1.2 1.4e-32 111.8 0.8 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KZN86842.1 - 7.8e-26 90.0 0.0 3.1e-25 88.1 0.0 2.0 2 0 0 2 2 2 1 PCRF domain Mito_carr PF00153.22 KZN86843.1 - 8.4e-56 185.6 5.5 1.7e-22 78.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.24 KZN86844.1 - 2.6e-41 140.9 0.0 3.8e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN86844.1 - 8.7e-24 83.1 0.1 1.6e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SMC_N PF02463.14 KZN86845.1 - 8.6e-21 74.1 11.7 4.6e-20 71.8 8.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KZN86845.1 - 6.8e-18 65.7 6.4 6.8e-18 65.7 4.4 5.4 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 KZN86845.1 - 1.3e-09 38.4 1.2 8.1e-06 26.0 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN86845.1 - 0.00014 21.3 0.0 0.00034 20.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KZN86845.1 - 0.00069 18.7 3.2 0.00069 18.7 2.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain TPR_MLP1_2 PF07926.7 KZN86845.1 - 0.0019 17.9 16.2 0.0019 17.9 11.2 6.2 3 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein SbcCD_C PF13558.1 KZN86845.1 - 0.002 17.9 0.3 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 KZN86845.1 - 0.087 13.1 0.2 0.087 13.1 0.2 5.4 3 2 0 3 3 3 0 ABC transporter PAP_assoc PF03828.14 KZN86846.1 - 0.00078 19.3 0.0 0.0053 16.6 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase Glyco_transf_20 PF00982.16 KZN86847.1 - 1.5e-150 501.7 0.0 3e-150 500.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KZN86847.1 - 1.1e-90 302.6 0.0 1.8e-90 301.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.11 KZN86848.1 - 5.3e-17 61.5 57.0 8.6e-16 57.5 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 KZN86849.1 - 1.3e-30 105.2 19.2 1.3e-30 105.2 13.3 3.2 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 UNC-50 PF05216.8 KZN86850.1 - 1.3e-84 283.0 5.0 1.6e-84 282.7 3.5 1.1 1 0 0 1 1 1 1 UNC-50 family YobH PF13996.1 KZN86850.1 - 7.3 6.5 7.1 0.4 10.6 0.8 2.0 2 0 0 2 2 2 0 YobH-like protein Sec7 PF01369.15 KZN86851.1 - 2.8e-41 141.3 0.0 6e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KZN86851.1 - 5e-20 71.8 0.1 1.3e-18 67.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Tektin PF03148.9 KZN86851.1 - 0.032 12.7 0.3 0.051 12.1 0.2 1.2 1 0 0 1 1 1 0 Tektin family Microtub_assoc PF07989.6 KZN86852.1 - 1.1e-23 82.8 10.0 1.1e-23 82.8 6.9 7.6 9 1 0 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 KZN86852.1 - 1.7e-21 76.0 30.3 5.3e-18 64.8 11.8 12.1 13 3 1 14 14 14 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KZN86852.1 - 3.1e-05 23.3 4.5 3.1e-05 23.3 3.1 5.6 4 2 1 5 5 5 2 Reovirus sigma C capsid protein Orthopox_A36R PF05950.6 KZN86852.1 - 0.0015 18.4 0.9 0.0054 16.6 0.6 2.0 1 0 0 1 1 1 1 Orthopoxvirus A36R protein Fib_alpha PF08702.5 KZN86852.1 - 1.6 8.8 56.1 0.027 14.5 4.6 6.6 3 2 3 6 6 6 0 Fibrinogen alpha/beta chain family QRPTase_C PF01729.14 KZN86853.1 - 6.5e-48 162.4 0.2 2.7e-46 157.1 0.2 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KZN86853.1 - 3.8e-25 87.5 0.0 1.1e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 KZN86853.1 - 0.041 12.9 0.0 0.19 10.8 0.0 2.0 1 1 2 3 3 3 0 Ribulose-phosphate 3 epimerase family Aldose_epim PF01263.15 KZN86854.1 - 4.4e-61 206.5 0.0 4.9e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.13 KZN86855.1 - 8.1e-09 35.2 13.2 1.4e-08 34.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KZN86855.1 - 0.64 9.3 10.6 0.79 9.0 7.4 1.2 1 0 0 1 1 1 0 Vta1 like Ras PF00071.17 KZN86856.1 - 2.2e-28 98.6 0.0 4.8e-27 94.3 0.0 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN86856.1 - 1.4e-05 25.6 0.0 1.4e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KZN86856.1 - 0.06 12.7 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 KZN86856.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family PAS_9 PF13426.1 KZN86857.1 - 1.3e-27 96.2 0.0 1.5e-18 67.0 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KZN86857.1 - 2.3e-17 62.8 0.0 2.7e-11 43.4 0.0 3.7 3 0 0 3 3 3 2 PAS fold GATA PF00320.22 KZN86857.1 - 2.7e-14 52.1 7.2 7.3e-14 50.8 5.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KZN86857.1 - 5.2e-12 45.5 0.0 0.00057 19.6 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.5 KZN86857.1 - 8e-08 32.3 0.0 0.0069 16.4 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.1 KZN86857.1 - 2.1e-06 27.6 0.0 0.017 15.0 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.1 KZN86857.1 - 0.0013 18.4 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain LETM1 PF07766.8 KZN86858.1 - 1.1e-05 24.6 2.0 0.073 12.0 0.1 2.2 1 1 0 2 2 2 2 LETM1-like protein Nrap PF03813.9 KZN86859.1 - 0 1141.3 0.0 0 1141.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 KZN86860.1 - 1.7e-29 102.2 0.0 2.2e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KZN86860.1 - 0.00032 19.7 0.0 0.00052 19.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MRP-L20 PF12824.2 KZN86862.1 - 2.2e-62 209.8 4.2 2.5e-62 209.6 2.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 KZN86862.1 - 0.0027 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Neugrin Peptidase_M20 PF01546.23 KZN86863.1 - 1.8e-30 105.8 0.0 2.9e-30 105.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN86863.1 - 5e-14 51.9 0.0 7.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Amidohydro_5 PF13594.1 KZN86863.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase PLDc PF00614.17 KZN86864.1 - 4.4e-14 51.7 0.4 1.1e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KZN86864.1 - 2.8e-12 46.4 0.0 4.4e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KZN86864.1 - 3.7e-07 29.9 0.1 2.5e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 PX domain DUF313 PF03754.8 KZN86864.1 - 0.076 12.9 0.2 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Abhydrolase_6 PF12697.2 KZN86865.1 - 4.4e-07 30.0 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN86865.1 - 5.6e-06 26.1 0.0 1.1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PBP_like_2 PF12849.2 KZN86865.1 - 0.064 12.7 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 PBP superfamily domain Ribosomal_L18e PF00828.14 KZN86866.1 - 1.6e-33 115.8 0.0 2e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 KZN86867.1 - 5.7e-57 192.3 0.0 1.5e-56 190.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KZN86867.1 - 1.6e-46 157.8 0.0 4.1e-46 156.5 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KZN86867.1 - 0.036 13.8 0.3 3.6 7.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Lipoprotein_6 PF01441.14 KZN86867.1 - 0.084 12.7 2.6 0.17 11.6 0.5 2.3 2 0 0 2 2 2 0 Lipoprotein AAA_22 PF13401.1 KZN86867.1 - 0.095 12.8 0.0 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.7 KZN86868.1 - 7.1e-20 70.9 15.1 1.9e-07 31.4 0.0 6.8 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 KZN86868.1 - 0.00018 20.9 0.1 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KZN86868.1 - 0.017 14.7 0.2 0.017 14.7 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 KZN86868.1 - 0.041 14.5 3.5 0.15 12.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN86868.1 - 0.084 12.8 0.0 0.084 12.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN86868.1 - 0.1 13.2 0.1 0.1 13.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TBPIP PF07106.8 KZN86869.1 - 8.9e-22 77.4 0.8 1.1e-21 77.1 0.6 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 KZN86869.1 - 0.00034 19.0 2.0 0.0004 18.8 1.4 1.0 1 0 0 1 1 1 1 Transmembrane protein PspA_IM30 PF04012.7 KZN86869.1 - 0.01 15.1 4.5 0.083 12.2 3.1 2.1 1 1 0 1 1 1 0 PspA/IM30 family DUF3106 PF11304.3 KZN86869.1 - 0.019 15.3 2.2 0.029 14.7 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) WEMBL PF05701.6 KZN86869.1 - 0.023 13.1 6.9 0.021 13.3 4.0 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Snapin_Pallidin PF14712.1 KZN86869.1 - 0.043 14.1 0.9 0.097 12.9 0.6 1.5 1 0 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 KZN86869.1 - 0.075 12.2 2.0 0.15 11.2 1.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Wbp11 PF09429.5 KZN86869.1 - 0.075 13.0 5.7 3.2 7.7 0.4 2.8 1 1 1 2 2 2 0 WW domain binding protein 11 Penicillinase_R PF03965.11 KZN86869.1 - 0.078 13.0 0.9 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Penicillinase repressor DUF4140 PF13600.1 KZN86869.1 - 0.2 12.1 6.5 1.2 9.5 0.5 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.5 KZN86869.1 - 0.24 11.2 8.1 0.029 14.3 2.7 1.6 2 0 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) DUF1192 PF06698.6 KZN86869.1 - 0.55 10.0 9.1 3.4 7.5 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF572 PF04502.8 KZN86869.1 - 0.68 9.0 4.5 0.86 8.7 3.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCDC-167 PF15188.1 KZN86869.1 - 0.86 9.5 8.7 0.86 9.5 1.4 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF904 PF06005.7 KZN86869.1 - 2.2 8.6 9.9 3.8 7.8 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Prefoldin_2 PF01920.15 KZN86869.1 - 3.2 7.5 9.7 1.7 8.4 0.3 3.0 2 1 1 3 3 3 0 Prefoldin subunit IncA PF04156.9 KZN86869.1 - 8.3 5.9 8.3 1.4 8.4 3.1 1.7 2 0 0 2 2 2 0 IncA protein zf-CCCH PF00642.19 KZN86870.1 - 1.6e-11 43.5 10.7 8.6e-06 25.3 1.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KZN86870.1 - 0.84 9.7 16.0 2.3 8.3 2.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Bromodomain PF00439.20 KZN86871.1 - 2.8e-12 46.3 0.1 4.2e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Bromodomain OTU PF02338.14 KZN86872.1 - 1.1e-12 48.5 0.0 2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KZN86872.1 - 0.0069 15.7 0.0 0.025 13.9 0.0 1.7 1 1 1 2 2 2 1 Peptidase C65 Otubain UN_NPL4 PF11543.3 KZN86872.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pkinase PF00069.20 KZN86873.1 - 2.8e-41 141.4 0.0 1.7e-18 66.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86873.1 - 5.8e-09 35.4 0.0 0.00064 18.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KZN86873.1 - 0.00028 20.6 0.1 0.94 9.1 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN86873.1 - 0.0082 15.1 0.0 0.95 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Cnd1_N PF12922.2 KZN86874.1 - 8.5e-58 194.7 0.0 2.3e-57 193.3 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KZN86874.1 - 5.9e-56 189.1 4.8 4.3e-51 173.2 0.3 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KZN86874.1 - 9e-13 48.3 3.7 9.4e-07 29.0 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KZN86874.1 - 3.2e-07 30.6 9.6 0.042 14.3 0.1 6.4 6 0 0 6 6 6 3 HEAT-like repeat HEAT PF02985.17 KZN86874.1 - 3.5e-07 29.7 13.3 0.2 11.8 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 KZN86874.1 - 2.7e-06 25.9 10.6 0.00085 17.7 0.3 4.0 4 2 0 4 4 4 2 Adaptin N terminal region DUF2435 PF10363.4 KZN86874.1 - 0.0045 16.8 0.0 1.5 8.7 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) FlbD PF06289.6 KZN86874.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) Cnd3 PF12719.2 KZN86874.1 - 0.73 8.7 11.2 0.098 11.6 1.7 3.5 3 2 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 KZN86874.1 - 2.7 8.0 6.1 7.4 6.6 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Oxysterol_BP PF01237.13 KZN86875.1 - 1.4e-57 194.8 0.0 3.4e-57 193.5 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_C12 PF01088.16 KZN86876.1 - 1.5e-62 210.5 0.3 2.9e-62 209.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 P4Ha_N PF08336.6 KZN86876.1 - 0.092 12.5 1.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region I-set PF07679.11 KZN86877.1 - 1.2e-06 28.2 1.0 0.021 14.6 0.0 5.0 6 0 0 6 6 6 3 Immunoglobulin I-set domain SWM_repeat PF13753.1 KZN86877.1 - 0.0008 18.5 0.0 0.078 12.0 0.0 2.5 2 0 0 2 2 2 2 Putative flagellar system-associated repeat Arylesterase PF01731.15 KZN86878.1 - 0.00028 20.8 0.0 0.003 17.4 0.0 2.6 2 1 0 2 2 2 1 Arylesterase ZZ PF00569.12 KZN86879.1 - 4.3e-22 77.3 56.2 3.8e-08 32.7 3.1 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 KZN86880.1 - 4.3e-30 104.4 4.1 4.3e-30 104.4 2.8 1.9 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 KZN86881.1 - 4.3e-26 90.3 0.7 2e-14 52.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86881.1 - 2e-24 85.3 0.1 4.4e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86881.1 - 5.9e-09 35.6 0.1 4.6e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 KZN86881.1 - 2.4 8.3 15.3 2.5 8.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Ino80_Iec3 PF14612.1 KZN86882.1 - 4.8e-90 301.6 3.3 7.6e-90 301.0 2.3 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Nucleo_P87 PF07267.6 KZN86882.1 - 0.26 9.9 6.1 0.52 8.9 4.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ECR1_N PF14382.1 KZN86883.1 - 5.3e-11 41.6 0.1 1.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KZN86883.1 - 0.00083 19.2 0.1 0.014 15.3 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 IFRD PF05004.8 KZN86884.1 - 2.2e-33 115.6 0.1 3.2e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KZN86884.1 - 0.00047 20.3 0.5 1.4 9.2 0.0 3.1 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KZN86884.1 - 0.001 18.9 0.6 0.73 10.0 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Cnd3 PF12719.2 KZN86884.1 - 0.0034 16.4 0.1 0.0078 15.2 0.1 1.7 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain DUF4062 PF13271.1 KZN86884.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Sigma70_ner PF04546.8 KZN86884.1 - 0.13 11.8 11.2 0.69 9.4 2.1 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Oxysterol_BP PF01237.13 KZN86885.1 - 6e-119 396.6 0.0 1.6e-118 395.2 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KZN86885.1 - 1.3e-38 130.9 0.1 2.6e-38 129.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KZN86885.1 - 8.6e-06 25.9 0.1 5.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KZN86885.1 - 9.4e-05 22.6 1.7 0.002 18.3 1.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 KZN86885.1 - 0.022 14.9 0.0 0.081 13.1 0.0 2.0 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PH_3 PF14593.1 KZN86885.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 PH domain SH2_2 PF14633.1 KZN86886.1 - 9.9e-84 279.8 0.1 3.3e-83 278.0 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KZN86886.1 - 7e-38 129.2 5.4 7e-38 129.2 3.8 2.8 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 KZN86886.1 - 2.4e-31 107.9 0.0 4.7e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KZN86886.1 - 1.4e-27 96.1 0.0 3.9e-27 94.6 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 KZN86886.1 - 2.2e-19 69.6 3.1 2.8e-18 66.0 2.1 2.7 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 KZN86886.1 - 7.4e-19 67.7 19.9 7.4e-19 67.7 13.8 5.5 5 1 1 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 KZN86886.1 - 0.00019 21.2 0.0 0.00049 19.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KZN86886.1 - 0.0017 18.2 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.14 KZN86886.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 KZN86887.1 - 4.3e-61 206.3 0.0 5.6e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN86887.1 - 3.3e-36 124.6 0.0 4.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN86887.1 - 1.5e-05 24.1 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KZN86887.1 - 0.024 13.5 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KZN86887.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KZN86887.1 - 0.16 11.6 0.0 0.8 9.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN86887.1 - 0.2 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HUN PF08729.5 KZN86889.1 - 7e-14 51.4 0.1 7e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 KZN86890.1 - 1.1e-29 102.0 0.0 2.2e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KZN86890.1 - 4.2e-18 64.6 9.1 2.1e-17 62.4 6.4 2.1 2 0 0 2 2 2 1 RPAP1-like, N-terminal Apc1 PF12859.2 KZN86892.1 - 3.8e-31 107.4 0.2 1.1e-30 105.9 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KZN86892.1 - 1.1e-05 25.3 12.2 0.12 12.6 0.1 4.5 5 0 0 5 5 5 3 Proteasome/cyclosome repeat eIF2A PF08662.6 KZN86893.1 - 2.3e-81 272.1 0.0 1.5e-80 269.5 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KZN86893.1 - 3.4e-06 26.7 0.1 0.066 13.1 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 KZN86893.1 - 0.0039 17.2 0.4 0.0039 17.2 0.3 4.1 3 1 0 3 3 3 1 Carnitine deficiency-associated protein 3 Acetyltransf_13 PF13880.1 KZN86896.1 - 1.6e-29 101.4 0.0 3.6e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KZN86896.1 - 7.9e-17 60.5 0.2 1.5e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 KZN86897.1 - 1.6e-79 265.9 0.1 1.8e-79 265.7 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 KZN86898.1 - 1.6e-08 35.1 0.0 3.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KZN86898.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.10 KZN86898.1 - 0.014 15.0 3.1 0.033 13.8 2.1 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 KZN86898.1 - 0.037 13.6 4.2 0.079 12.6 2.9 1.5 1 0 0 1 1 1 0 Glycine zipper UQ_con PF00179.21 KZN86899.1 - 2.9e-51 172.5 0.0 3.3e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN86899.1 - 6.9e-05 22.6 0.0 7.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KZN86899.1 - 0.0053 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KZN86899.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 KZN86900.1 - 1.4e-26 93.3 0.1 3.3e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KZN86900.1 - 6.4e-25 88.0 1.5 1.2e-24 87.1 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN86900.1 - 1.3e-16 59.8 0.0 2.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN86900.1 - 6.7e-09 36.0 1.4 6.7e-09 36.0 1.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 KZN86901.1 - 1.1e-05 24.4 0.4 2.5e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86901.1 - 0.074 12.9 0.8 0.13 12.2 0.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.13 KZN86902.1 - 1.2e-29 102.1 0.0 3.2e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KZN86902.1 - 1.9e-27 95.5 0.3 8.2e-27 93.4 0.0 2.3 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KZN86902.1 - 9.6e-05 22.5 0.5 0.00054 20.1 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 KZN86902.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PcfK PF14058.1 KZN86902.1 - 0.95 9.6 11.3 1.4 9.1 3.4 3.0 3 0 0 3 3 3 0 PcfK-like protein Linker_histone PF00538.14 KZN86903.1 - 3.5e-23 81.4 0.4 7.1e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.13 KZN86904.1 - 2.1e-87 292.4 0.1 3.3e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIID_20kDa PF03847.8 KZN86905.1 - 5.3e-21 74.6 0.0 9.2e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 KZN86905.1 - 0.036 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN86905.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Kelch_5 PF13854.1 KZN86906.1 - 0.00017 21.4 4.1 0.0017 18.2 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.11 KZN86906.1 - 0.081 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 KZN86906.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Kelch_6 PF13964.1 KZN86906.1 - 2.3 8.5 4.9 11 6.4 0.1 3.7 2 1 1 3 3 3 0 Kelch motif DASH_Spc34 PF08657.5 KZN86907.1 - 1.1e-66 225.2 2.8 3.6e-65 220.2 1.9 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 IncA PF04156.9 KZN86907.1 - 0.00021 20.9 0.1 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 IncA protein DASH_Spc19 PF08287.6 KZN86907.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Spc19 Myosin_tail_1 PF01576.14 KZN86907.1 - 0.041 11.5 0.2 0.063 11.0 0.1 1.2 1 0 0 1 1 1 0 Myosin tail EndoU_bacteria PF14436.1 KZN86907.1 - 0.051 13.4 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial EndoU nuclease DUF465 PF04325.8 KZN86907.1 - 0.056 13.1 1.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Prefoldin_2 PF01920.15 KZN86907.1 - 0.12 12.1 0.2 8.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Tim44 PF04280.10 KZN86907.1 - 0.28 11.1 1.5 0.64 9.9 0.1 1.9 2 0 0 2 2 2 0 Tim44-like domain Rpn3_C PF08375.6 KZN86908.1 - 2.5e-25 88.6 0.6 9e-25 86.8 0.4 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KZN86908.1 - 3.3e-19 69.1 0.4 2e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KZN86908.1 - 0.00051 19.8 0.1 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 polyprenyl_synt PF00348.12 KZN86909.1 - 3.4e-51 173.5 0.0 3.6e-48 163.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF2404 PF10296.4 KZN86910.1 - 2.2e-30 104.6 0.0 4.2e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ANTH PF07651.11 KZN86911.1 - 1.1e-78 263.7 0.0 1.1e-78 263.7 0.0 2.7 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KZN86911.1 - 2.7e-64 215.7 4.7 2.7e-64 215.7 3.3 6.2 5 2 2 7 7 7 1 I/LWEQ domain ENTH PF01417.15 KZN86911.1 - 2.8e-05 23.9 0.1 0.0002 21.2 0.0 2.5 2 0 0 2 2 2 1 ENTH domain NFRKB_winged PF14465.1 KZN86911.1 - 0.19 11.5 3.3 3.7 7.4 0.4 3.8 3 1 1 4 4 4 0 NFRKB Winged Helix-like MAT_Alpha1 PF04769.7 KZN86912.1 - 3.6e-25 88.4 0.0 5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 PARP PF00644.15 KZN86914.1 - 1.6e-11 44.0 0.1 3e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KZN86914.1 - 4.8e-08 32.5 0.0 1.4e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN86914.1 - 0.037 13.7 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B Complex1_LYR_1 PF13232.1 KZN86916.1 - 9.6e-16 57.7 6.0 1.5e-15 57.0 4.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KZN86916.1 - 4.3e-14 52.0 5.0 4.3e-14 52.0 3.5 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KZN86916.1 - 0.0065 16.9 2.5 0.0086 16.5 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like IATP PF04568.7 KZN86916.1 - 0.96 9.5 4.8 0.27 11.2 1.0 1.8 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP hEGF PF12661.2 KZN86918.1 - 0.069 13.2 2.3 0.14 12.3 1.6 1.5 1 0 0 1 1 1 0 Human growth factor-like EGF Baculo_11_kDa PF06143.6 KZN86918.1 - 0.57 9.5 1.7 1.1 8.6 1.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.1 KZN86918.1 - 2.3 7.9 9.1 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family EGF_2 PF07974.8 KZN86918.1 - 7.1 6.8 11.7 12 6.1 8.1 1.4 1 0 0 1 1 1 0 EGF-like domain ATP-sulfurylase PF01747.12 KZN86919.1 - 4.7e-87 290.8 0.0 6.7e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KZN86919.1 - 2e-59 199.7 0.0 3.1e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KZN86919.1 - 4.3e-52 175.7 0.0 7.3e-52 174.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 KZN86919.1 - 0.086 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KZN86919.1 - 0.12 12.6 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SET PF00856.23 KZN86920.1 - 4.7e-16 59.5 0.4 4.7e-16 59.5 0.3 3.6 3 3 0 3 3 3 1 SET domain zf-DHHC PF01529.15 KZN86921.1 - 2e-34 118.5 6.2 2e-34 118.5 4.3 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PMT PF02366.13 KZN86923.1 - 7.1e-79 264.6 17.4 7.1e-79 264.6 12.1 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KZN86923.1 - 3.4e-53 180.0 0.0 6.9e-53 179.0 0.0 1.5 2 0 0 2 2 2 1 MIR domain DUF4231 PF14015.1 KZN86923.1 - 0.071 13.0 1.4 0.27 11.2 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PRP21_like_P PF12230.3 KZN86924.1 - 5.3e-63 212.5 9.3 8.3e-63 211.9 6.5 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KZN86924.1 - 2.7e-33 113.3 5.3 1.3e-16 59.9 0.2 2.5 2 0 0 2 2 2 2 Surp module DUF1517 PF07466.6 KZN86924.1 - 0.068 12.1 1.3 0.12 11.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) zf-Di19 PF05605.7 KZN86924.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Sec2p PF06428.6 KZN86925.1 - 4.1e-28 97.1 11.3 4.1e-28 97.1 7.8 1.9 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4250 PF14056.1 KZN86925.1 - 0.1 12.3 0.6 0.28 10.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) YjgP_YjgQ PF03739.9 KZN86925.1 - 0.86 8.2 1.5 1.2 7.7 1.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Coq4 PF05019.8 KZN86926.1 - 9.8e-99 328.7 0.0 1.2e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 KZN86927.1 - 5e-20 72.4 0.0 8.9e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 SET domain ApbA_C PF08546.6 KZN86928.1 - 2.4e-33 114.7 0.0 3.9e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KZN86928.1 - 1.5e-21 76.4 0.0 3.3e-21 75.3 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.10 KZN86929.1 - 4.8e-18 65.1 1.2 4.8e-18 65.1 0.8 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 KZN86929.1 - 2.2 5.8 11.9 2.2 5.8 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2076 PF09849.4 KZN86930.1 - 2.8e-09 37.3 11.9 3.3e-09 37.1 8.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KZN86930.1 - 0.00025 20.8 1.3 0.00047 19.9 0.9 1.6 1 0 0 1 1 1 1 CHCH domain CDC27 PF09507.5 KZN86930.1 - 0.61 9.2 3.3 0.74 8.9 2.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gly-zipper_OmpA PF13436.1 KZN86930.1 - 0.62 9.7 13.1 0.67 9.6 8.6 1.6 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain UBX PF00789.15 KZN86931.1 - 2.2e-09 37.2 0.0 4.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain SURF1 PF02104.10 KZN86932.1 - 4e-67 226.1 0.0 5.2e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 KZN86933.1 - 6.4e-94 315.5 19.7 1.7e-93 314.1 13.6 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 KZN86933.1 - 1.2e-07 31.8 0.1 2.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KZN86933.1 - 0.003 17.6 0.1 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN86933.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CMS1 PF14617.1 KZN86934.1 - 1.6e-80 269.8 4.2 2.1e-80 269.4 2.9 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KZN86934.1 - 7.4e-05 22.3 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.17 KZN86935.1 - 1e-12 47.4 0.0 2.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86935.1 - 4e-10 39.5 0.0 9.1e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86935.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 KZN86936.1 - 5.1e-55 185.2 0.0 5.9e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN86936.1 - 1e-17 64.7 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN86936.1 - 1.2e-07 31.1 0.0 1.5e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MAM1 PF10434.4 KZN86936.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 ABM PF03992.11 KZN86937.1 - 5.4e-13 48.7 0.0 7.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase YqeY PF09424.5 KZN86937.1 - 0.052 13.3 0.9 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Yqey-like protein Fungal_trans PF04082.13 KZN86938.1 - 8.8e-09 34.6 0.1 1.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN86938.1 - 2.4e-07 30.5 9.8 2.4e-07 30.5 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.22 KZN86939.1 - 6.4e-49 165.4 0.0 2.3e-48 163.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KZN86939.1 - 2e-14 53.5 0.3 7.1e-14 51.7 0.2 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Flagellin_N PF00669.15 KZN86939.1 - 0.11 12.3 4.9 2.6 7.8 0.1 2.6 1 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region MBA1 PF07961.6 KZN86940.1 - 2.3e-07 29.9 0.0 3.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.3 KZN86941.1 - 6.7e-31 106.9 14.9 1.4e-25 89.6 6.0 2.2 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.17 KZN86942.1 - 7.2e-29 99.4 5.8 1e-28 98.9 4.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Med12 PF09497.5 KZN86943.1 - 1.1e-26 92.5 0.4 3.1e-26 91.1 0.3 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ACDC PF14733.1 KZN86943.1 - 0.0095 16.0 0.2 2.5 8.2 0.0 2.8 2 0 0 2 2 2 2 AP2-coincident C-terminal RRM_1 PF00076.17 KZN86944.1 - 2.5e-11 43.0 0.1 3.5e-07 29.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN86944.1 - 8.6e-07 28.8 0.0 5.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN86944.1 - 0.0022 17.8 0.0 0.62 9.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 KZN86945.1 - 3.4e-39 134.2 0.1 5.9e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 KZN86945.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.13 KZN86946.1 - 6.7e-89 297.2 0.0 7.8e-89 297.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 KZN86947.1 - 2.1e-31 107.5 5.9 2.1e-31 107.5 4.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 KZN86947.1 - 0.0064 16.8 0.0 3.1 8.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN86947.1 - 0.028 14.3 6.9 11 6.0 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN86947.1 - 0.14 12.1 0.7 1.4 8.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN86947.1 - 0.14 12.0 1.8 4.5 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.13 KZN86948.1 - 4.8e-09 35.9 11.0 8.5e-09 35.1 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnAC PF14619.1 KZN86948.1 - 0.051 13.7 0.8 0.4 10.8 0.0 2.6 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Ring_hydroxyl_A PF00848.14 KZN86949.1 - 1.3e-41 142.5 4.7 3e-41 141.3 3.3 1.6 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) CorC_HlyC PF03471.12 KZN86949.1 - 0.019 14.7 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Transporter associated domain DIPSY PF11763.3 KZN86949.1 - 0.028 14.2 0.4 0.21 11.3 0.0 2.4 2 1 1 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal Glyco_tranf_2_3 PF13641.1 KZN86950.1 - 3.1e-38 131.8 0.0 4.8e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KZN86950.1 - 5.5e-22 78.4 1.0 5.5e-22 78.4 0.7 3.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 KZN86950.1 - 7.3e-14 51.0 3.6 2.8e-09 35.8 0.1 2.9 2 1 1 3 3 3 2 Cellulose synthase Glycos_transf_2 PF00535.21 KZN86950.1 - 1.2e-12 47.8 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KZN86950.1 - 3.2e-12 46.0 0.0 5.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 KZN86950.1 - 0.0084 14.5 0.1 0.049 12.0 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase Glyco_hydro_12 PF01670.11 KZN86951.1 - 1.4e-16 60.6 1.9 2.7e-16 59.7 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 MFS_1 PF07690.11 KZN86952.1 - 6.8e-20 71.0 34.0 6.8e-20 71.0 23.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN86952.1 - 3e-07 30.0 6.5 3e-07 30.0 4.5 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2406 PF10295.4 KZN86953.1 - 9.1e-21 74.1 0.2 9.1e-21 74.1 0.1 2.8 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.3 KZN86954.1 - 1.7e-13 50.7 8.0 3.4e-10 40.1 2.6 3.7 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) Mito_carr PF00153.22 KZN86955.1 - 1.8e-46 155.8 7.8 2.6e-17 62.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 KZN86956.1 - 0.00043 20.0 0.0 0.23 11.2 0.0 3.1 2 1 1 3 3 3 2 CBS domain VMA21 PF09446.5 KZN86957.1 - 4.8e-20 71.2 6.7 6.8e-20 70.7 4.6 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 KZN86958.1 - 3.5e-62 209.8 0.6 5e-62 209.3 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN86958.1 - 9.2e-15 54.2 0.0 2.3e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN86958.1 - 7.5e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN86958.1 - 2.2e-06 27.2 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 KZN86958.1 - 0.061 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Dus PF01207.12 KZN86959.1 - 6.4e-43 146.7 0.0 1.3e-42 145.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.14 KZN86960.1 - 7.9e-51 171.5 0.2 1e-50 171.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 KZN86961.1 - 1.3e-18 66.6 0.0 2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 KZN86962.1 - 3.8e-15 55.3 1.8 3.8e-15 55.3 1.2 2.1 2 0 0 2 2 2 1 Sec20 Laminin_II PF06009.7 KZN86962.1 - 0.28 10.9 9.8 1.3 8.7 1.9 3.7 3 2 1 4 4 4 0 Laminin Domain II Syntaxin-6_N PF09177.6 KZN86962.1 - 0.29 11.5 6.2 0.95 9.9 0.1 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal AAA PF00004.24 KZN86963.1 - 6.1e-15 55.5 0.0 2e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KZN86963.1 - 1.1e-12 47.8 0.0 2.7e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KZN86963.1 - 1.2e-10 41.1 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KZN86963.1 - 3.4e-10 39.2 0.0 5.4e-08 31.9 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KZN86963.1 - 1.2e-07 31.9 0.0 2.1e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KZN86963.1 - 2.6e-06 26.6 0.0 9e-06 24.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KZN86963.1 - 6.4e-05 23.0 0.1 0.0013 18.7 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KZN86963.1 - 7.9e-05 22.3 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KZN86963.1 - 0.00012 21.7 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KZN86963.1 - 0.00021 20.4 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KZN86963.1 - 0.00044 20.1 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KZN86963.1 - 0.0022 17.0 0.0 0.0044 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KZN86963.1 - 0.0024 17.4 1.5 0.0044 16.6 0.2 2.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KZN86963.1 - 0.0052 16.2 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_5 PF07728.9 KZN86963.1 - 0.0065 16.1 0.1 0.041 13.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KZN86963.1 - 0.014 14.8 0.2 0.04 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KZN86963.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KZN86963.1 - 0.025 15.3 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KZN86963.1 - 0.03 14.6 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 KZN86963.1 - 0.046 13.2 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 KZN86963.1 - 0.051 13.0 0.1 0.72 9.2 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KZN86963.1 - 0.073 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN86963.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KZN86963.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 KZN86965.1 - 1.8e-06 27.7 10.6 3.9e-06 26.6 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.1 KZN86965.1 - 0.37 10.4 8.0 0.16 11.6 3.0 2.1 2 0 0 2 2 2 0 Cytochrome c7 DUF1275 PF06912.6 KZN86966.1 - 5.7e-35 120.4 10.8 7.5e-35 120.0 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SKG6 PF08693.5 KZN86969.1 - 0.023 13.9 1.5 0.04 13.2 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 KZN86969.1 - 0.03 14.0 1.9 0.061 13.0 1.3 1.4 1 1 0 1 1 1 0 Glycophorin A Med3 PF11593.3 KZN86969.1 - 0.35 10.0 3.3 0.47 9.6 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3270 PF11674.3 KZN86971.1 - 0.0096 15.9 0.3 0.0096 15.9 0.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3270) BatA PF07584.6 KZN86971.1 - 7.7 6.7 8.0 37 4.6 2.0 2.7 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Hydrolase_6 PF13344.1 KZN86972.1 - 2.7e-30 104.2 0.0 5.8e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN86972.1 - 1e-12 48.9 0.0 1.6e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN86972.1 - 9.9e-12 44.4 0.0 7.1e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KZN86972.1 - 1.2e-06 28.9 0.1 2.7e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 KZN86972.1 - 0.039 13.3 0.0 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Acid_phosphat_B PF03767.9 KZN86972.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HTH_42 PF06224.7 KZN86973.1 - 0.0046 16.3 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain NUDIX PF00293.23 KZN86976.1 - 3.5e-07 29.9 0.1 1.6e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain LETM1 PF07766.8 KZN86977.1 - 1e-101 339.5 0.1 1.7e-101 338.8 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein DUF2838 PF10998.3 KZN86978.1 - 7.6e-45 151.3 10.2 7.6e-45 151.3 7.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 KZN86978.1 - 0.013 14.4 3.6 0.024 13.5 2.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2841 PF11001.3 KZN86979.1 - 2.1e-45 153.6 0.1 3.1e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Glyco_hydro_62 PF03664.8 KZN86980.1 - 3.7e-151 501.7 14.9 4.3e-151 501.5 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_10 PF00331.15 KZN86981.1 - 3e-104 348.4 0.0 3.5e-104 348.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Lipase_3 PF01764.20 KZN86982.1 - 2.3e-36 124.5 0.0 3.3e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KZN86982.1 - 0.00034 20.0 0.5 0.0089 15.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.15 KZN86982.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 KZN86982.1 - 0.0068 16.6 0.1 0.0093 16.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Cutinase PF01083.17 KZN86982.1 - 0.019 14.7 1.5 0.04 13.6 1.0 1.6 1 1 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 KZN86982.1 - 0.038 13.7 0.1 0.066 12.9 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family SMC_N PF02463.14 KZN86984.1 - 3e-60 203.2 0.4 6.5e-59 198.8 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KZN86984.1 - 7.7e-31 106.5 0.0 3.6e-30 104.3 0.0 2.3 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KZN86984.1 - 5e-11 43.0 0.1 2.4e-06 27.7 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.1 KZN86984.1 - 2.4e-08 33.3 0.0 6.3e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KZN86984.1 - 2.7e-07 31.1 31.3 2.7e-07 31.1 21.7 6.5 3 2 2 5 5 4 2 AAA domain MAD PF05557.8 KZN86984.1 - 2.6e-05 22.5 27.2 2.6e-05 22.5 18.8 4.2 3 1 1 4 4 4 2 Mitotic checkpoint protein DUF4200 PF13863.1 KZN86984.1 - 0.00022 21.1 5.5 0.00022 21.1 3.8 8.4 4 2 4 8 8 5 1 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 KZN86984.1 - 0.001 18.3 16.0 0.69 9.0 0.1 4.5 3 1 1 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 KZN86984.1 - 0.0011 18.8 0.0 0.0066 16.3 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 KZN86984.1 - 0.0037 16.8 13.5 0.0037 16.8 9.4 7.0 3 2 3 6 6 4 2 IncA protein TPR_MLP1_2 PF07926.7 KZN86984.1 - 0.0098 15.6 0.1 0.0098 15.6 0.1 7.6 5 2 2 7 7 6 3 TPR/MLP1/MLP2-like protein AAA_22 PF13401.1 KZN86984.1 - 0.035 14.2 1.4 7 6.8 0.0 4.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.22 KZN86984.1 - 0.82 9.9 0.0 0.82 9.9 0.0 6.5 4 2 1 5 5 4 0 ABC transporter AAA_13 PF13166.1 KZN86984.1 - 2.2 6.6 97.4 0.029 12.8 10.7 6.2 3 2 2 6 6 6 0 AAA domain E3_binding PF02817.12 KZN86986.1 - 9.8e-08 31.5 0.1 9.8e-08 31.5 0.1 2.6 3 0 0 3 3 3 1 e3 binding domain WD40 PF00400.27 KZN86987.1 - 1.1e-39 132.8 2.7 6.4e-08 32.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KZN86987.1 - 6.4e-09 35.7 0.1 0.0048 16.6 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A ATPgrasp_ST PF14397.1 KZN86987.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp TFIIA PF03153.8 KZN86987.1 - 0.34 10.7 2.1 0.45 10.3 1.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M18 PF02127.10 KZN86988.1 - 9.3e-166 551.6 0.0 1.1e-165 551.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF1746 PF08508.5 KZN86989.1 - 9.8e-38 128.6 2.5 1.4e-37 128.2 1.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.18 KZN86990.1 - 5.8e-74 247.6 0.0 7.7e-74 247.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 KZN86990.1 - 0.085 12.6 0.4 0.34 10.6 0.3 1.8 1 1 0 1 1 1 0 Peptidase family S49 DHDPS PF00701.17 KZN86990.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family adh_short PF00106.20 KZN86994.1 - 2.7e-17 63.2 0.9 1.8e-16 60.5 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN86994.1 - 6.9e-11 42.1 0.1 9.3e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KZN86994.1 - 5.7e-05 22.1 0.1 0.0001 21.3 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KZN86994.1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KZN86994.1 - 0.0057 16.1 0.1 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KZN86994.1 - 0.0061 15.9 0.1 1.6 8.0 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family adh_short_C2 PF13561.1 KZN86994.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Lipoprotein_18 PF06804.6 KZN86994.1 - 0.096 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein NAD_binding_4 PF07993.7 KZN86994.1 - 0.12 11.2 0.1 0.48 9.3 0.1 1.9 1 1 0 1 1 1 0 Male sterility protein ADH_N PF08240.7 KZN86995.1 - 7.5e-11 41.7 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN86995.1 - 3.5e-10 40.8 0.0 8.9e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN86995.1 - 1.4e-08 34.3 0.0 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SLT PF01464.15 KZN86996.1 - 0.00055 19.4 0.3 0.0017 17.8 0.2 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.15 KZN86996.1 - 0.0015 18.4 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 LysM domain DUF4425 PF14466.1 KZN86996.1 - 0.0086 16.2 0.6 0.02 15.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4425) DUF605 PF04652.11 KZN86996.1 - 0.072 12.4 10.6 0.097 12.0 7.4 1.2 1 0 0 1 1 1 0 Vta1 like HILPDA PF15220.1 KZN86996.1 - 0.8 9.7 2.5 1.9 8.5 1.7 1.6 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated AA_permease_2 PF13520.1 KZN86997.1 - 7.6e-65 219.1 43.0 1e-64 218.6 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN86997.1 - 1.2e-25 89.8 37.9 1.6e-25 89.4 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KZN86997.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 3.8 3 0 0 3 3 3 1 Gram positive anchor YwiC PF14256.1 KZN86998.1 - 3.2 7.8 8.4 0.18 11.9 0.7 2.4 2 1 0 2 2 2 0 YwiC-like protein Transferase PF02458.10 KZN86999.1 - 2.3e-22 79.0 0.0 9.1e-21 73.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family MGDG_synth PF06925.6 KZN86999.1 - 0.037 13.9 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_hydro_38 PF01074.17 KZN87000.1 - 5.3e-92 307.9 1.5 5.3e-92 307.9 1.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KZN87000.1 - 2.3e-73 247.5 0.0 4.1e-73 246.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KZN87000.1 - 1.2e-25 89.5 0.0 2.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NuA4 PF09340.5 KZN87001.1 - 5e-28 96.5 0.2 5e-28 96.5 0.1 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Tmemb_cc2 PF10267.4 KZN87001.1 - 0.65 8.5 0.0 0.65 8.5 0.0 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Ctr PF04145.10 KZN87002.1 - 2.9e-35 121.4 2.3 3.7e-35 121.0 1.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Wzy_C PF04932.10 KZN87002.1 - 0.07 12.9 1.4 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase Cupin_8 PF13621.1 KZN87003.1 - 1.9e-14 53.7 0.0 6.6e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KZN87003.1 - 5.2e-10 39.5 0.0 5.2e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KZN87003.1 - 3e-07 30.0 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN87003.1 - 0.013 15.0 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain DEAD PF00270.24 KZN87004.1 - 2.6e-42 144.2 1.0 5e-42 143.2 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN87004.1 - 1.2e-27 95.6 0.5 4.1e-27 93.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN87004.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KZN87004.1 - 0.0032 17.0 0.1 0.0085 15.6 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN87004.1 - 0.0034 17.5 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN87004.1 - 0.0059 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SNF2_N PF00176.18 KZN87004.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CMS1 PF14617.1 KZN87004.1 - 0.081 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.9 KZN87004.1 - 0.083 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein FAA_hydrolase PF01557.13 KZN87005.1 - 5.4e-53 179.6 0.0 6.5e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family UDPGT PF00201.13 KZN87007.1 - 7.1e-07 28.1 0.0 9.8e-07 27.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase p450 PF00067.17 KZN87008.1 - 8.5e-59 199.2 0.0 1.1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GHL12 PF14882.1 KZN87008.1 - 0.21 11.7 1.5 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 DAO PF01266.19 KZN87009.1 - 2.6e-23 82.5 0.4 1.2e-22 80.2 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN87009.1 - 0.00018 21.8 1.2 0.00041 20.7 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN87009.1 - 0.00046 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KZN87009.1 - 0.00082 18.5 0.4 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN87009.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KZN87009.1 - 0.0018 17.6 0.1 0.0018 17.6 0.1 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KZN87009.1 - 0.0034 16.2 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KZN87009.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN87009.1 - 0.037 13.3 0.2 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KZN87009.1 - 0.047 12.1 0.2 0.067 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KZN87009.1 - 0.062 13.3 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KZN87009.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 KZN87009.1 - 0.08 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AA_permease PF00324.16 KZN87010.1 - 4.2e-72 243.0 38.2 5.2e-72 242.7 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN87010.1 - 1.3e-19 70.0 43.3 1.7e-19 69.6 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF373 PF04123.8 KZN87010.1 - 2 7.3 13.5 0.37 9.7 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Fungal_trans_2 PF11951.3 KZN87011.1 - 2.7e-31 108.5 2.4 2.1e-27 95.7 0.4 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain MBOAT_2 PF13813.1 KZN87012.1 - 1e-24 86.3 2.3 3.1e-24 84.8 1.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 KZN87013.1 - 4e-43 147.4 45.7 4e-43 147.4 31.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN87013.1 - 4e-18 64.9 14.9 4e-18 64.9 10.3 2.4 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN87013.1 - 2.1e-12 46.4 13.1 2.1e-12 46.4 9.1 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 KZN87013.1 - 3.1e-08 32.5 11.8 3.1e-08 32.5 8.2 2.5 3 1 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KZN87014.1 - 4.3e-21 75.0 38.0 1.5e-20 73.2 18.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87014.1 - 1.8e-14 53.1 19.6 5.5e-14 51.6 13.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3794 PF12673.2 KZN87014.1 - 0.039 14.1 0.1 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) YrhC PF14143.1 KZN87014.1 - 4.8 7.2 6.1 12 5.9 0.6 2.8 2 0 0 2 2 2 0 YrhC-like protein PhyH PF05721.8 KZN87015.1 - 4.6e-07 30.0 0.1 1.1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KZN87015.1 - 8.6e-06 24.4 0.3 0.055 11.9 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.13 KZN87016.1 - 2.4e-40 138.6 0.5 4.9e-39 134.3 0.1 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KZN87016.1 - 8.8e-26 91.1 0.0 1.2e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KZN87016.1 - 2.3e-06 27.6 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN87016.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN87016.1 - 0.038 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 KZN87016.1 - 0.3 9.5 1.0 7.5 4.9 0.0 2.4 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 KZN87017.1 - 5.2e-18 64.8 0.1 1.2e-17 63.6 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87017.1 - 5e-09 35.9 14.0 8.9e-09 35.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 KZN87018.1 - 1e-06 28.9 0.2 2.5e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KZN87018.1 - 1.3e-05 23.9 0.0 0.16 10.4 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 KZN87019.1 - 1.4e-07 30.6 0.6 2.3e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PWI PF01480.12 KZN87021.1 - 6.4e-28 96.6 0.0 1.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.20 KZN87022.1 - 1e-47 162.5 0.0 1.5e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87022.1 - 8.2e-17 61.1 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN87022.1 - 0.00068 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KZN87022.1 - 0.0014 18.0 0.2 0.0028 17.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN87022.1 - 0.035 13.8 0.1 0.22 11.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KZN87022.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 KZN87022.1 - 0.096 10.7 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Choline_kinase PF01633.15 KZN87022.1 - 0.13 11.8 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S8e PF01201.17 KZN87023.1 - 2.8e-27 95.4 0.6 4.2e-27 94.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Enkurin PF13864.1 KZN87023.1 - 0.18 12.0 0.1 0.18 12.0 0.0 1.5 2 0 0 2 2 2 0 Calmodulin-binding RIB43A PF05914.7 KZN87024.1 - 0.0016 17.1 0.2 0.0025 16.5 0.1 1.2 1 0 0 1 1 1 1 RIB43A Ribosomal_L21p PF00829.16 KZN87024.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Fungal_trans PF04082.13 KZN87025.1 - 1.3e-23 83.2 0.2 2.6e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87025.1 - 0.0012 18.6 6.7 0.0028 17.5 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.11 KZN87026.1 - 2.3e-27 95.3 1.8 2.7e-27 95.0 1.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.11 KZN87027.1 - 2e-65 220.1 0.0 2.8e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KZN87027.1 - 0.11 13.0 0.0 0.98 10.0 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain zf-GRF PF06839.7 KZN87028.1 - 7.6e-07 28.9 5.1 1.6e-06 27.9 3.5 1.6 1 0 0 1 1 1 1 GRF zinc finger TMF_TATA_bd PF12325.3 KZN87028.1 - 0.059 13.1 0.4 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ank_2 PF12796.2 KZN87029.1 - 7.4e-78 256.9 0.0 1.8e-14 53.8 0.0 6.2 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87029.1 - 3.2e-52 171.8 0.8 2e-06 27.2 0.0 10.6 10 1 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KZN87029.1 - 4.4e-46 154.4 0.4 8.4e-12 45.2 0.0 7.3 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN87029.1 - 8.5e-39 130.7 6.9 2.7e-10 40.1 0.1 9.2 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87029.1 - 8.7e-38 124.5 0.0 0.00043 20.2 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat DUF3818 PF12825.2 KZN87030.1 - 2.5e-104 348.6 2.4 3.5e-104 348.1 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Vps5 PF09325.5 KZN87030.1 - 0.0048 16.1 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 Vps5 C terminal like DUF2373 PF10180.4 KZN87030.1 - 0.066 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Ku_PK_bind PF08785.6 KZN87030.1 - 0.28 11.1 1.7 1.4 8.8 0.1 2.6 2 1 1 3 3 3 0 Ku C terminal domain like PXB PF12828.2 KZN87031.1 - 1.8e-41 140.9 0.1 3.9e-41 139.8 0.1 1.5 1 0 0 1 1 1 1 PX-associated DUF3818 PF12825.2 KZN87031.1 - 1.3e-17 63.4 0.0 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.19 KZN87031.1 - 2.3e-15 56.3 0.9 1.3e-14 53.9 0.1 2.6 2 1 0 2 2 2 1 PX domain zf-C2H2 PF00096.21 KZN87032.1 - 0.00018 21.6 2.6 0.00018 21.6 1.8 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87032.1 - 0.21 12.0 21.2 0.21 12.0 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN87032.1 - 0.26 11.6 19.0 3.8 7.9 2.6 3.6 3 0 0 3 3 3 0 Zinc-finger double domain NAD_Gly3P_dh_N PF01210.18 KZN87034.1 - 1.4e-48 164.5 0.0 2.4e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KZN87034.1 - 8e-35 119.7 0.0 1.3e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus GerE PF00196.14 KZN87034.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family F420_oxidored PF03807.12 KZN87034.1 - 0.1 13.0 0.0 14 6.2 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Catalase PF00199.14 KZN87035.1 - 9.1e-166 551.2 0.4 1.2e-165 550.8 0.3 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN87035.1 - 5.7e-18 64.5 0.0 1.1e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KZN87035.1 - 0.0067 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans_2 PF11951.3 KZN87036.1 - 1.2e-28 99.8 1.8 1.6e-28 99.4 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2600 PF10776.4 KZN87036.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) HD PF01966.17 KZN87037.1 - 0.00018 21.5 0.0 0.00029 20.8 0.0 1.5 1 1 0 1 1 1 1 HD domain adh_short PF00106.20 KZN87038.1 - 4.8e-27 94.9 0.3 3e-26 92.3 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87038.1 - 4.7e-22 78.9 0.4 7.8e-22 78.2 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87038.1 - 7.3e-11 42.0 1.6 2.2e-09 37.2 1.1 2.2 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KZN87038.1 - 4.6e-05 23.5 0.5 0.00015 21.8 0.3 1.9 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KZN87038.1 - 0.00058 19.9 0.4 0.0058 16.6 0.1 2.3 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KZN87038.1 - 0.0014 17.7 1.6 0.0058 15.8 1.1 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 KZN87038.1 - 0.0086 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_tran_WecB PF03808.8 KZN87038.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family SRI PF08236.6 KZN87038.1 - 0.1 12.5 0.2 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain adh_short PF00106.20 KZN87039.1 - 1.3e-24 86.9 0.7 1.9e-24 86.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87039.1 - 3.4e-20 72.8 0.1 4.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87039.1 - 5.6e-11 42.4 0.4 1e-10 41.5 0.3 1.3 1 0 0 1 1 1 1 KR domain AAA PF00004.24 KZN87041.1 - 7.5e-48 162.0 0.0 3.8e-43 146.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KZN87041.1 - 5.2e-05 22.7 0.0 0.00023 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN87041.1 - 8.9e-05 23.2 0.0 0.0013 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN87041.1 - 0.00018 21.6 0.0 0.0066 16.5 0.0 3.5 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KZN87041.1 - 0.0002 20.4 0.0 0.00045 19.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KZN87041.1 - 0.00047 19.1 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KZN87041.1 - 0.00077 19.4 1.4 0.025 14.5 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KZN87041.1 - 0.0015 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KZN87041.1 - 0.0031 17.4 0.0 0.0078 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KZN87041.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KZN87041.1 - 0.0055 15.4 0.0 0.0087 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 KZN87041.1 - 0.0064 16.2 0.0 0.028 14.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KZN87041.1 - 0.021 13.9 0.1 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN87041.1 - 0.022 14.5 0.0 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KZN87041.1 - 0.032 13.3 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 KZN87041.1 - 0.037 14.3 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KZN87041.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 KZN87041.1 - 0.054 13.3 0.1 0.28 11.0 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_28 PF13521.1 KZN87041.1 - 0.06 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KZN87041.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KZN87041.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KZN87041.1 - 0.22 10.0 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase CEP1-DNA_bind PF09287.5 KZN87042.1 - 0.091 12.1 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 CEP-1, DNA binding KGG PF10685.4 KZN87043.1 - 1.5e-26 91.7 22.4 8.8e-11 41.4 2.0 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif CHZ PF09649.5 KZN87044.1 - 0.019 14.2 0.9 0.029 13.6 0.1 1.7 2 0 0 2 2 2 0 Histone chaperone domain CHZ Glyco_transf_20 PF00982.16 KZN87045.1 - 1.2e-144 482.3 0.0 1.7e-144 481.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KZN87045.1 - 9.6e-37 126.1 0.0 1.4e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CAS_CSE1 PF03378.10 KZN87045.1 - 0.082 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus AA_permease_2 PF13520.1 KZN87046.1 - 5.2e-53 180.1 53.3 6.3e-53 179.8 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN87046.1 - 2.6e-16 59.0 43.6 3.7e-16 58.5 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KZN87046.1 - 0.32 10.8 0.0 0.32 10.8 0.0 3.9 5 0 0 5 5 5 0 Gram positive anchor DUF4243 PF14027.1 KZN87047.1 - 1.9e-66 224.8 0.0 2.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 KZN87048.1 - 1.1e-90 303.8 0.0 1.3e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 KZN87048.1 - 0.11 12.5 0.2 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rifin_STEVOR PF02009.11 KZN87048.1 - 0.13 11.8 0.2 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family TauD PF02668.11 KZN87049.1 - 7.7e-54 183.0 0.3 9.1e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KZN87050.1 - 5.1e-25 87.9 19.7 8.2e-25 87.2 13.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN87050.1 - 0.00065 19.4 1.8 0.0011 18.6 0.2 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF4500 PF14937.1 KZN87050.1 - 0.017 14.9 0.2 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Cupin_2 PF07883.6 KZN87051.1 - 0.087 12.3 0.6 0.18 11.2 0.4 1.5 1 1 0 1 1 1 0 Cupin domain PI-PLC-X PF00388.14 KZN87052.1 - 5.3e-50 168.6 1.7 3.8e-49 165.8 1.2 2.3 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KZN87052.1 - 3.9e-36 123.6 2.2 7.9e-36 122.6 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain CENP-B_dimeris PF09026.5 KZN87052.1 - 1.2 9.4 4.3 3.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GST_N_3 PF13417.1 KZN87053.1 - 2.2e-09 37.3 0.1 7e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN87053.1 - 3e-05 23.9 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN87053.1 - 0.0037 17.1 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN87053.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.5 KZN87054.1 - 1.8e-28 97.9 4.8 2e-27 94.5 3.3 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Epimerase PF01370.16 KZN87055.1 - 3.5e-35 121.5 0.0 2.3e-34 118.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KZN87055.1 - 6.6e-13 48.3 0.1 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KZN87055.1 - 2.4e-08 33.2 0.0 2.5e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KZN87055.1 - 1.2e-06 27.6 0.0 9.4e-06 24.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KZN87055.1 - 5.2e-06 25.3 0.0 4e-05 22.4 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN87055.1 - 3.7e-05 23.6 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN87055.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KZN87055.1 - 0.00035 19.5 0.0 0.0047 15.8 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN87055.1 - 0.048 13.6 0.0 0.84 9.6 0.0 2.7 3 1 0 3 3 3 0 NADH(P)-binding Spherulin4 PF12138.3 KZN87056.1 - 2.6e-75 253.1 0.2 3e-75 252.9 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Ferrochelatase PF00762.14 KZN87056.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase Glyco_hydro_114 PF03537.8 KZN87057.1 - 2.9e-23 81.4 0.1 5.1e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.5 KZN87057.1 - 1.7 8.6 3.8 0.46 10.4 0.2 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Glycos_transf_1 PF00534.15 KZN87059.1 - 2.9e-12 46.3 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KZN87059.1 - 2.5e-05 23.9 0.0 0.00013 21.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KZN87059.1 - 0.0002 21.5 0.0 0.00096 19.3 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 DPPIV_N PF00930.16 KZN87060.1 - 4e-111 371.0 0.2 7.1e-111 370.2 0.0 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KZN87060.1 - 1.4e-52 178.0 1.4 2.3e-52 177.3 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN87060.1 - 3.8e-08 33.1 0.0 7.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KZN87060.1 - 5.1e-05 22.8 2.2 0.00015 21.3 1.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KZN87060.1 - 0.00018 21.4 0.2 0.0012 18.7 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KZN87060.1 - 0.0029 15.9 0.0 1.4 7.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 KZN87060.1 - 0.0087 15.5 0.1 0.027 13.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 KZN87060.1 - 0.014 13.9 0.0 0.045 12.2 0.0 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KZN87060.1 - 0.051 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cpn60_TCP1 PF00118.19 KZN87061.1 - 1.9e-137 458.8 8.6 2.4e-137 458.5 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3184 PF11380.3 KZN87061.1 - 0.041 11.8 1.0 0.059 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) GTP1_OBG PF01018.17 KZN87061.1 - 0.081 12.5 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 GTP1/OBG AAA PF00004.24 KZN87062.1 - 1.1e-40 138.8 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN87062.1 - 4.9e-06 26.7 0.0 0.0006 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KZN87062.1 - 5.5e-05 22.9 0.1 0.0003 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN87062.1 - 0.00024 21.1 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KZN87062.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KZN87062.1 - 0.002 17.1 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KZN87062.1 - 0.0039 18.0 0.1 0.012 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KZN87062.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KZN87062.1 - 0.01 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KZN87062.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KZN87062.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KZN87062.1 - 0.032 13.8 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KZN87062.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KZN87062.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KZN87062.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KZN87062.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KZN87062.1 - 0.087 13.1 0.1 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KZN87062.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KZN87062.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FAD_binding_2 PF00890.19 KZN87063.1 - 1.7e-125 419.1 3.9 2.1e-125 418.8 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KZN87063.1 - 3.3e-46 156.2 0.8 5e-46 155.7 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KZN87063.1 - 1.8e-08 34.4 0.0 0.0017 18.2 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN87063.1 - 8.1e-06 25.1 0.2 0.0086 15.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KZN87063.1 - 2.8e-05 23.1 0.7 0.016 14.1 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KZN87063.1 - 3.2e-05 23.0 1.1 0.001 18.0 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KZN87063.1 - 0.0015 17.6 0.2 0.003 16.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PAPS_reduct PF01507.14 KZN87063.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.9 KZN87063.1 - 0.21 9.9 1.9 0.83 8.0 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein Adeno_E3_CR2 PF02439.10 KZN87064.1 - 6.7e-05 22.3 6.6 0.00013 21.4 4.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mid2 PF04478.7 KZN87064.1 - 0.00081 18.8 0.3 0.00081 18.8 0.2 2.7 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Beta-APP PF03494.8 KZN87064.1 - 0.0024 17.2 4.8 0.0049 16.3 3.3 1.4 1 0 0 1 1 1 1 Beta-amyloid peptide (beta-APP) EphA2_TM PF14575.1 KZN87064.1 - 0.0031 17.8 0.0 0.0062 16.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KZN87064.1 - 0.0034 16.6 1.7 0.0085 15.3 1.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 KZN87064.1 - 0.0039 16.0 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 KZN87064.1 - 0.0047 15.2 0.0 0.0069 14.6 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Plasmodium_Vir PF05795.6 KZN87064.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lyase_1 PF00206.15 KZN87065.1 - 3e-83 279.5 0.0 5e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KZN87065.1 - 1.3e-25 89.1 0.1 4.5e-25 87.4 0.1 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Membralin PF09746.4 KZN87065.1 - 0.12 11.3 0.0 0.26 10.3 0.0 1.5 1 1 0 1 1 1 0 Tumour-associated protein FR47 PF08445.5 KZN87066.1 - 5.2e-07 29.3 0.0 0.0021 17.7 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 KZN87066.1 - 0.0017 18.5 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN87066.1 - 0.02 14.8 0.2 0.062 13.3 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Fungal_trans PF04082.13 KZN87069.1 - 4.7e-10 38.7 1.6 9.1e-10 37.8 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN87069.1 - 3.8e-05 23.7 22.5 0.00045 20.3 2.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KZN87069.1 - 5.1e-05 23.0 10.7 5.1e-05 23.0 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KZN87069.1 - 0.00016 21.7 19.8 0.00018 21.6 0.9 3.8 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN87069.1 - 0.0012 18.9 3.4 0.0012 18.9 2.4 4.4 4 1 1 5 5 5 2 C2H2-type zinc finger p450 PF00067.17 KZN87071.1 - 7.2e-72 242.3 0.0 8.8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SH3_9 PF14604.1 KZN87073.1 - 1.3e-23 82.3 0.2 7.9e-12 44.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KZN87073.1 - 3.8e-22 78.2 0.3 1.1e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KZN87073.1 - 2.1e-19 68.6 1.0 4.1e-10 38.8 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.17 KZN87073.1 - 1e-14 53.9 5.6 2.2e-14 52.8 3.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KZN87073.1 - 9.1e-05 21.8 0.0 0.069 12.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KZN87073.1 - 0.0082 16.3 0.2 0.092 12.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.11 KZN87073.1 - 0.13 12.3 7.2 0.23 11.6 5.0 1.4 1 0 0 1 1 1 0 C1 domain Cortex-I_coil PF09304.5 KZN87073.1 - 0.6 10.1 7.2 2.3 8.3 0.1 3.7 2 1 1 3 3 3 0 Cortexillin I, coiled coil DEAD PF00270.24 KZN87074.1 - 4.6e-31 107.5 2.0 1.8e-30 105.6 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN87074.1 - 5.5e-22 77.4 0.1 1.1e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KZN87074.1 - 0.027 14.2 0.5 0.28 10.9 0.0 2.7 2 1 1 3 3 3 0 Part of AAA domain Fungal_trans PF04082.13 KZN87075.1 - 8.2e-11 41.2 0.2 2e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87075.1 - 1.2e-06 28.2 7.2 2.5e-06 27.3 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_CH_N PF12471.3 KZN87076.1 - 2.7e-90 301.2 0.0 3.8e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KZN87076.1 - 2.7e-17 62.5 0.0 4.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.16 KZN87076.1 - 0.15 11.5 0.0 5.2 6.5 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family DUF2014 PF09427.5 KZN87077.1 - 2.5e-100 334.9 0.1 3.8e-100 334.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 KZN87077.1 - 2.5e-18 65.4 0.5 7.5e-18 63.9 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NUDE_C PF04880.8 KZN87077.1 - 0.0011 19.3 2.8 0.0011 19.3 2.0 2.9 3 0 0 3 3 3 1 NUDE protein, C-terminal conserved region Leu_zip PF15294.1 KZN87077.1 - 0.0038 16.3 0.4 0.0064 15.6 0.2 1.2 1 0 0 1 1 1 1 Leucine zipper bZIP_1 PF00170.16 KZN87077.1 - 0.064 13.2 3.5 0.047 13.6 0.6 2.1 2 0 0 2 2 2 0 bZIP transcription factor NAD_binding_6 PF08030.7 KZN87078.1 - 2.8e-19 69.5 0.0 1.5e-18 67.2 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KZN87078.1 - 1.2e-14 54.4 10.1 1.2e-14 54.4 7.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN87078.1 - 3.1e-12 46.2 0.0 2.8e-11 43.2 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KZN87078.1 - 0.0079 16.7 0.1 0.3 11.6 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF3043 PF11241.3 KZN87078.1 - 0.53 9.8 2.1 0.44 10.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF3632 PF12311.3 KZN87079.1 - 1.2e-22 80.6 0.2 2.2e-22 79.7 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) FSH1 PF03959.8 KZN87080.1 - 1.4e-31 109.6 0.0 2.8e-31 108.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.21 KZN87081.1 - 5.5e-13 48.5 0.0 3.4e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN87081.1 - 3e-07 30.1 0.0 1e-05 25.2 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN87081.1 - 0.002 19.0 0.0 0.0065 17.3 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.15 KZN87082.1 - 9.7e-62 207.9 6.2 1.9e-61 207.0 4.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN87082.1 - 7.4e-32 110.3 2.7 7.4e-32 110.3 1.9 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN87082.1 - 8.6e-28 98.2 0.1 5.4e-27 95.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN87082.1 - 2.8e-14 52.3 0.0 8.4e-14 50.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KZN87082.1 - 1.8e-13 51.1 0.3 6.3e-13 49.3 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN87082.1 - 3.9e-13 49.1 0.0 7.7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN87082.1 - 7.3e-07 29.0 2.2 1.4e-05 24.7 1.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 KZN87082.1 - 0.012 15.2 0.8 0.036 13.6 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) RNase_PH PF01138.16 KZN87083.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 KZN87084.1 - 1e-69 234.5 0.0 1.3e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase SSP160 PF06933.6 KZN87085.1 - 0.19 9.6 5.9 0.25 9.2 4.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NmrA PF05368.8 KZN87086.1 - 2.2e-22 79.4 0.0 1.3e-20 73.6 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN87086.1 - 9.4e-06 25.7 0.1 1.4e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN87086.1 - 0.16 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GAF_2 PF13185.1 KZN87087.1 - 2.1e-08 34.7 0.0 4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 KZN87087.1 - 2.6e-06 27.6 0.0 3.6e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KZN87087.1 - 0.00023 21.2 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 GAF domain adh_short PF00106.20 KZN87088.1 - 2.3e-35 121.9 0.1 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87088.1 - 4.4e-21 75.7 0.1 5.1e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87088.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN87088.1 - 1.7e-05 24.4 0.1 3.1e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KZN87088.1 - 4.3e-05 23.2 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KZN87088.1 - 6.2e-05 21.8 0.1 8.1e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 KZN87088.1 - 9.5e-05 22.7 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KZN87088.1 - 0.00021 20.2 0.1 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN87088.1 - 0.00045 20.2 0.2 0.0018 18.2 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 KZN87088.1 - 0.0012 19.1 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KZN87088.1 - 0.0048 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KZN87088.1 - 0.0065 16.0 0.1 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain RmlD_sub_bind PF04321.12 KZN87088.1 - 0.0088 14.9 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 KZN87088.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.1 KZN87088.1 - 0.02 15.1 0.1 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KZN87088.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KZN87088.1 - 0.03 13.7 0.2 0.066 12.6 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.11 KZN87088.1 - 0.037 14.4 0.1 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KZN87088.1 - 0.049 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KZN87088.1 - 0.066 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AdoHcyase_NAD PF00670.16 KZN87088.1 - 0.073 12.9 3.1 0.32 10.8 2.2 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sod_Cu PF00080.15 KZN87089.1 - 2e-40 138.1 1.4 2.3e-40 137.9 1.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) UBN2_3 PF14244.1 KZN87090.1 - 0.0096 15.4 0.2 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type adh_short PF00106.20 KZN87091.1 - 1.6e-17 63.9 0.2 2.1e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN87091.1 - 9.9e-10 38.3 0.2 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN87091.1 - 2.3e-05 23.9 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2893 PF11459.3 KZN87091.1 - 0.062 13.1 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) GFA PF04828.9 KZN87092.1 - 7.8e-14 51.3 1.5 1.5e-13 50.4 1.0 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KZN87092.1 - 0.032 14.0 2.3 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF35_N PF12172.3 KZN87092.1 - 0.81 9.6 7.4 5.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Metallophos PF00149.23 KZN87094.1 - 2.8e-06 26.8 8.5 1.4e-05 24.6 5.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MARVEL PF01284.18 KZN87095.1 - 7.3e-30 103.6 8.5 8.5e-30 103.4 5.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain zf-C2HC5 PF06221.8 KZN87095.1 - 0.022 14.5 0.3 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SUR7 PF06687.7 KZN87095.1 - 0.18 11.3 7.7 0.056 12.9 3.5 1.5 1 1 0 1 1 1 0 SUR7/PalI family Clat_adaptor_s PF01217.15 KZN87096.1 - 3.2e-53 179.2 1.6 3.8e-53 179.0 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.3 KZN87096.1 - 0.042 12.4 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Maf1 PF09174.5 KZN87097.1 - 1.6e-62 210.5 0.0 2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Filament PF00038.16 KZN87098.1 - 7.4e-07 28.9 20.0 7.4e-07 28.9 13.9 4.6 2 1 3 5 5 5 2 Intermediate filament protein WEMBL PF05701.6 KZN87098.1 - 0.00011 20.8 47.0 0.00011 20.8 32.6 1.8 2 0 0 2 2 2 1 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 KZN87098.1 - 0.0018 18.0 13.8 0.0018 18.0 9.6 5.0 4 1 1 5 5 5 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KZN87098.1 - 0.0096 15.7 2.9 0.0096 15.7 2.0 6.9 7 0 0 7 7 7 3 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KZN87098.1 - 0.72 8.9 18.8 2.2 7.3 6.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 KZN87098.1 - 4.3 7.1 65.7 0.024 14.4 13.5 5.6 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) COPIIcoated_ERV PF07970.7 KZN87099.1 - 7.9e-33 113.9 0.1 5.1e-32 111.3 0.1 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KZN87099.1 - 4.4e-23 81.0 0.0 8.8e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 KZN87100.1 - 1.3e-59 201.4 0.0 1.9e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87100.1 - 4.2e-20 71.8 0.0 8.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN87100.1 - 0.12 12.1 0.0 0.63 9.7 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pex24p PF06398.6 KZN87101.1 - 5.6e-90 301.7 0.0 8.2e-90 301.1 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 KZN87101.1 - 0.0023 16.1 0.8 0.0035 15.5 0.6 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 KZN87101.1 - 0.68 7.7 2.2 0.87 7.3 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Nop16 PF09420.5 KZN87102.1 - 5.3e-55 185.9 7.6 6.1e-55 185.7 5.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Borrelia_REV PF03978.8 KZN87102.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Zip PF02535.17 KZN87103.1 - 5.5e-59 199.7 5.9 1.2e-58 198.6 4.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.9 KZN87104.1 - 1.3e-106 355.7 0.0 1.6e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glyco_tranf_2_3 PF13641.1 KZN87104.1 - 0.13 12.0 0.3 0.5 10.1 0.2 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KZN87104.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.22 KZN87105.1 - 1.1e-45 153.2 2.1 3.3e-18 65.1 0.1 3.8 3 1 1 4 4 4 3 Mitochondrial carrier protein tRNA-synt_1b PF00579.20 KZN87107.1 - 2.7e-18 66.1 0.0 9.5e-18 64.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.14 KZN87108.1 - 2.1e-37 128.8 0.0 2.4e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 KZN87109.1 - 3.5e-47 157.9 20.0 4e-12 45.6 0.4 7.8 4 2 3 8 8 8 8 TPR repeat TPR_1 PF00515.23 KZN87109.1 - 2.7e-37 124.8 20.3 0.0012 18.3 0.0 11.3 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 KZN87109.1 - 1.6e-34 115.0 22.5 6.1e-05 22.6 0.0 11.1 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 KZN87109.1 - 1.9e-23 82.5 10.7 3e-05 24.5 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KZN87109.1 - 8.9e-20 70.4 27.5 1.4e-07 31.3 0.1 7.7 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KZN87109.1 - 1.6e-17 61.9 13.8 0.081 12.7 0.0 9.3 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KZN87109.1 - 8e-15 53.7 10.9 0.11 12.7 0.0 8.6 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KZN87109.1 - 5.6e-13 48.5 8.4 2.5e-05 24.0 0.1 5.8 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN87109.1 - 5.6e-12 45.1 14.5 0.037 14.6 0.0 8.0 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 KZN87109.1 - 5.9e-11 41.3 16.5 0.026 14.3 0.1 8.7 7 1 1 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN87109.1 - 4.1e-09 36.4 15.1 0.0046 17.0 0.2 5.2 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KZN87109.1 - 1.9e-07 31.3 21.5 2.1e-05 24.7 0.3 6.3 6 2 3 9 9 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 KZN87109.1 - 3.6e-05 22.9 5.1 0.89 8.8 0.0 5.9 5 0 0 5 5 5 1 SHNi-TPR MAS20 PF02064.10 KZN87109.1 - 6.4e-05 22.8 1.9 1.1 9.2 0.1 4.2 3 1 1 4 4 4 1 MAS20 protein import receptor TPR_6 PF13174.1 KZN87109.1 - 0.00045 20.4 21.3 3.3 8.3 0.5 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KZN87109.1 - 0.0007 19.4 5.3 2.5 8.1 0.3 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.5 KZN87109.1 - 0.0047 16.0 1.8 0.014 14.4 0.1 2.5 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like SpoIIIAH PF12685.2 KZN87109.1 - 0.0093 15.4 4.0 0.025 14.0 2.8 1.7 1 0 0 1 1 1 1 SpoIIIAH-like protein PPP4R2 PF09184.6 KZN87109.1 - 0.14 11.6 5.4 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 PPP4R2 Apc5 PF12862.2 KZN87109.1 - 0.25 11.1 9.8 12 5.8 0.0 4.2 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 5 Sel1 PF08238.7 KZN87109.1 - 6.8 7.4 8.9 0.85 10.3 0.1 3.9 4 0 0 4 4 3 0 Sel1 repeat FHA PF00498.21 KZN87110.1 - 9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-met PF12874.2 KZN87112.1 - 0.63 10.3 4.5 0.15 12.2 0.5 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PAT1 PF09770.4 KZN87112.1 - 1 7.5 14.3 1.2 7.3 9.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2 PF00096.21 KZN87112.1 - 1.2 9.5 14.0 3.9 7.9 2.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87112.1 - 5.7 7.5 9.2 28 5.3 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Zip PF02535.17 KZN87114.1 - 6.8e-46 156.7 11.4 8.2e-46 156.4 7.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PALP PF00291.20 KZN87115.1 - 3.8e-25 88.7 0.0 9.3e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3500 PF12006.3 KZN87116.1 - 4.2e-106 354.4 0.0 4.9e-106 354.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF2914 PF11141.3 KZN87116.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) L_HGMIC_fpl PF10242.4 KZN87117.1 - 8.3e-06 25.9 4.6 1.5e-05 25.0 3.2 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein ABC2_membrane PF01061.19 KZN87117.1 - 0.0037 16.4 0.7 0.069 12.2 0.2 2.1 2 0 0 2 2 2 1 ABC-2 type transporter DUF2232 PF09991.4 KZN87117.1 - 0.21 10.5 10.6 0.96 8.3 0.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2232) DUF1616 PF07760.6 KZN87117.1 - 0.22 10.6 2.8 0.89 8.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) Clc-like PF07062.7 KZN87117.1 - 0.95 8.6 5.5 3.6 6.7 0.0 2.3 1 1 1 2 2 2 0 Clc-like RRM_1 PF00076.17 KZN87118.1 - 8.6e-56 185.4 0.0 3.1e-20 71.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN87118.1 - 7.8e-44 147.5 0.2 2e-15 56.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN87118.1 - 4.9e-32 109.5 0.0 9.2e-14 51.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN87118.1 - 2.5e-09 36.7 0.0 0.093 12.5 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KZN87118.1 - 0.00057 19.1 1.1 0.0019 17.5 0.8 1.9 1 0 0 1 1 1 1 Lsm interaction motif U3_assoc_6 PF08640.6 KZN87118.1 - 0.017 14.8 1.6 0.34 10.7 0.5 2.8 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Nup35_RRM PF05172.8 KZN87118.1 - 0.059 13.1 0.0 0.88 9.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 KZN87118.1 - 0.084 12.3 0.0 23 4.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) TPR_14 PF13428.1 KZN87118.1 - 0.12 13.0 3.1 1.4 9.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.14 KZN87119.1 - 1.8e-16 59.9 0.2 1.8e-14 53.5 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.17 KZN87120.1 - 4.1e-22 78.9 0.1 6.7e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 KZN87122.1 - 5e-73 245.4 0.0 6.1e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87122.1 - 6.4e-36 123.7 0.0 8e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KZN87122.1 - 4.7e-09 36.3 0.0 9.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KZN87122.1 - 4.8e-06 25.7 0.0 8e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KZN87122.1 - 6.4e-05 22.3 0.1 0.00016 21.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family YukC PF10140.4 KZN87122.1 - 0.0099 14.4 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KZN87122.1 - 0.014 15.0 0.3 0.055 13.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KZN87122.1 - 0.016 14.2 0.1 0.025 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KZN87122.1 - 0.056 12.2 0.2 0.089 11.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KZN87122.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KZN87122.1 - 0.13 11.8 0.2 0.64 9.5 0.2 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase AAA_16 PF13191.1 KZN87124.1 - 7.6e-10 39.0 3.5 7.4e-08 32.5 0.1 3.0 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 KZN87124.1 - 4.5e-07 29.6 0.1 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KZN87124.1 - 9e-06 25.8 0.3 0.00072 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN87124.1 - 0.01 15.5 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 KZN87124.1 - 0.024 13.7 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KZN87124.1 - 0.031 14.5 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KZN87124.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain KAP_NTPase PF07693.9 KZN87124.1 - 0.085 11.8 1.4 1.5 7.7 0.0 2.8 2 1 0 3 3 3 0 KAP family P-loop domain AAA_29 PF13555.1 KZN87124.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KZN87124.1 - 0.19 12.5 1.3 0.64 10.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.16 KZN87125.1 - 1.4e-45 155.2 0.0 1.6e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family C2 PF00168.25 KZN87128.1 - 1.1e-10 41.1 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain UTP15_C PF09384.5 KZN87129.1 - 6.6e-53 178.3 1.9 6.6e-53 178.3 1.3 1.8 2 1 1 3 3 3 1 UTP15 C terminal WD40 PF00400.27 KZN87129.1 - 2.3e-27 93.8 0.4 8.2e-08 31.8 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KZN87129.1 - 0.00047 19.6 0.9 0.066 12.6 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain PhyH PF05721.8 KZN87130.1 - 5.9e-45 153.9 0.0 7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1826 PF08856.6 KZN87130.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) Sulfate_transp PF00916.15 KZN87132.1 - 1.5e-05 24.1 1.6 1.5e-05 24.1 1.1 3.3 2 1 1 3 3 3 1 Sulfate transporter family Sec62 PF03839.11 KZN87133.1 - 6.2 6.1 13.7 0.047 13.1 2.9 2.1 3 0 0 3 3 3 0 Translocation protein Sec62 ABC2_membrane PF01061.19 KZN87134.1 - 1.8e-88 295.1 70.3 4.3e-49 166.5 15.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KZN87134.1 - 8.8e-37 126.4 0.0 7.5e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN87134.1 - 1e-34 118.2 2.3 4.1e-31 106.6 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KZN87134.1 - 1.1e-18 67.0 0.3 4.6e-18 65.0 0.1 2.0 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KZN87134.1 - 2e-09 37.1 0.0 2.7e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 KZN87134.1 - 1.9e-08 33.7 56.5 8.4e-08 31.6 15.4 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KZN87134.1 - 2.6e-05 23.4 0.0 0.0053 15.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN87134.1 - 3.8e-05 23.7 0.1 0.0066 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KZN87134.1 - 7.7e-05 22.6 0.1 0.017 14.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KZN87134.1 - 0.00031 20.2 2.2 0.0012 18.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KZN87134.1 - 0.00092 18.6 2.2 0.04 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KZN87134.1 - 0.012 15.9 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KZN87134.1 - 0.015 15.4 0.0 0.79 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KZN87134.1 - 0.019 14.6 0.3 2.1 7.9 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KZN87134.1 - 0.023 15.5 0.0 0.3 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KZN87134.1 - 0.025 14.5 0.0 8.5 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 KZN87134.1 - 0.034 13.7 0.1 4 6.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN87134.1 - 0.05 13.3 0.4 2.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 KZN87134.1 - 0.086 12.4 1.2 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF1049 PF06305.6 KZN87134.1 - 2.4 7.6 6.9 18 4.9 0.2 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) UPF0546 PF10639.4 KZN87136.1 - 1.2e-36 124.9 0.1 1.6e-29 101.9 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 Chitin_synth_1 PF01644.12 KZN87137.1 - 3.7e-81 270.7 0.0 5.5e-81 270.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KZN87137.1 - 8.4e-30 102.2 0.0 1.8e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KZN87137.1 - 8.8e-23 80.4 4.1 3.8e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KZN87137.1 - 1.3e-08 34.8 3.5 1.3e-08 34.8 2.4 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN87137.1 - 1.7e-07 31.2 0.0 4.2e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 FxsA PF04186.8 KZN87137.1 - 0.0071 15.9 0.1 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 FxsA cytoplasmic membrane protein LMWPc PF01451.16 KZN87138.1 - 4.2e-31 108.0 0.0 3.5e-28 98.6 0.0 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 KZN87139.1 - 1.9e-61 206.5 0.5 2.3e-61 206.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KZN87139.1 - 3e-06 27.6 2.1 1.3e-05 25.4 1.5 1.9 1 1 0 1 1 1 1 Rubrerythrin UPF0184 PF03670.8 KZN87139.1 - 0.094 12.8 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Plus-3 PF03126.13 KZN87140.1 - 2.9e-30 104.5 0.0 2.3e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.5 KZN87141.1 - 1.1e-38 132.8 20.6 1.1e-38 132.8 14.3 5.6 5 1 1 6 6 6 1 MRC1-like domain KR PF08659.5 KZN87141.1 - 0.0019 17.8 1.8 0.0053 16.4 0.6 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KZN87141.1 - 0.064 13.1 2.3 0.61 9.9 1.1 2.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF2422 PF10337.4 KZN87141.1 - 3.3 6.3 5.5 7 5.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) 3HCDH_N PF02737.13 KZN87142.1 - 6.5e-23 81.3 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN87142.1 - 2.8e-21 75.6 0.0 7.3e-21 74.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain HAD_2 PF13419.1 KZN87143.1 - 2.5e-07 31.0 0.1 0.023 14.9 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN87143.1 - 5.1e-07 29.3 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN87143.1 - 0.13 12.6 0.0 1 9.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 KZN87144.1 - 1.1e-26 93.7 0.0 2e-26 92.8 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN87144.1 - 3e-19 69.7 0.4 6.1e-19 68.7 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN87144.1 - 6.8e-09 35.0 2.7 0.00016 20.7 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN87144.1 - 1.9e-07 30.3 0.5 0.0064 15.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KZN87144.1 - 7.6e-07 27.9 0.3 2e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KZN87144.1 - 9e-06 25.8 0.1 0.62 10.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN87144.1 - 4.6e-05 22.6 0.1 0.001 18.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN87144.1 - 0.00011 22.0 0.1 0.0095 15.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN87144.1 - 0.00011 22.0 0.0 0.00043 20.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN87144.1 - 0.00017 21.8 0.3 0.019 15.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN87144.1 - 0.00027 20.0 0.1 0.00059 19.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KZN87144.1 - 0.0037 16.3 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KZN87144.1 - 0.01 14.7 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN87144.1 - 0.026 13.4 0.1 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3638 PF12340.3 KZN87150.1 - 8.1e-95 316.1 0.2 1.5e-94 315.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KZN87150.1 - 1.1e-16 59.6 0.1 3.2e-16 58.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) FAD_binding_3 PF01494.14 KZN87151.1 - 1.4e-17 63.8 0.1 2.3e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN87151.1 - 2.9e-07 30.4 0.5 6.3e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN87151.1 - 0.0062 15.4 0.6 0.032 13.1 0.3 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN87151.1 - 0.016 14.0 1.6 0.03 13.1 0.4 2.0 3 0 0 3 3 3 0 FAD binding domain ThiF PF00899.16 KZN87151.1 - 0.02 14.7 0.1 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 ThiF family Pyr_redox_2 PF07992.9 KZN87151.1 - 0.026 14.3 0.5 0.061 13.1 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN87151.1 - 0.11 11.0 0.4 0.18 10.4 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 120_Rick_ant PF12574.3 KZN87151.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen UDPG_MGDP_dh_N PF03721.9 KZN87151.1 - 0.17 11.2 0.5 0.69 9.2 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Acetyltransf_2 PF00797.12 KZN87152.1 - 1.1e-42 146.2 0.0 2.3e-42 145.2 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase MIF4G PF02854.14 KZN87154.1 - 1.9e-20 73.2 0.2 4e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KZN87154.1 - 1.6e-18 66.4 0.1 1.7e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 KZN87155.1 - 1.1e-23 82.9 0.1 2.2e-23 81.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.3 KZN87155.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Inp1 PF12634.2 KZN87156.1 - 2.9e-35 121.0 0.0 6.4e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 KZN87157.1 - 0.00024 20.6 7.1 0.00024 20.6 4.9 3.5 2 2 0 3 3 3 1 Etoposide-induced protein 2.4 (EI24) DUF1700 PF08006.6 KZN87157.1 - 6.2 6.0 9.2 4.5 6.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) FmdA_AmdA PF03069.10 KZN87158.1 - 2.9e-155 516.5 0.0 3.3e-155 516.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Tyr_Deacylase PF02580.11 KZN87159.1 - 6.2e-46 155.9 0.0 7.9e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 KZN87160.1 - 1.5e-94 315.6 18.4 2e-94 315.2 12.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KZN87160.1 - 5e-43 146.1 10.6 1.1e-42 145.0 7.4 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Snapin_Pallidin PF14712.1 KZN87160.1 - 0.00066 19.9 7.7 0.014 15.6 0.3 2.6 2 1 0 2 2 2 2 Snapin/Pallidin Poty_PP PF08440.5 KZN87160.1 - 0.0041 16.2 1.2 0.0081 15.2 0.8 1.5 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 KZN87160.1 - 0.0085 15.6 3.0 0.023 14.2 2.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 KZN87160.1 - 0.018 14.9 7.4 0.028 14.3 0.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.6 KZN87160.1 - 0.073 12.8 3.3 0.14 12.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.1 KZN87160.1 - 0.57 10.2 7.9 0.1 12.6 1.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Syntaxin PF00804.20 KZN87160.1 - 1.4 9.1 10.2 1 9.5 3.0 2.8 3 0 0 3 3 3 0 Syntaxin DUF2951 PF11166.3 KZN87160.1 - 4 7.3 8.1 1.6 8.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.1 KZN87161.1 - 1.1e-05 25.3 14.3 0.0001 22.3 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN87161.1 - 7.2e-05 22.8 18.4 0.00012 22.2 0.9 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KZN87161.1 - 0.035 14.2 0.7 0.08 13.1 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KZN87161.1 - 0.89 9.9 14.8 0.75 10.2 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DNA_binding_1 PF01035.15 KZN87162.1 - 3.7e-26 90.6 0.1 7.3e-26 89.7 0.0 1.5 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF2914 PF11141.3 KZN87162.1 - 0.12 11.8 0.4 12 5.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Sugar_tr PF00083.19 KZN87163.1 - 5.7e-81 272.3 24.6 6.7e-81 272.1 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87163.1 - 6.1e-20 71.2 49.8 7.7e-15 54.4 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 KZN87164.1 - 1.7e-07 30.6 0.1 2.8e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 KZN87165.1 - 4.9e-43 147.1 22.8 7.9e-43 146.5 15.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87165.1 - 9.4e-09 34.3 11.1 9.4e-09 34.3 7.7 1.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KZN87165.1 - 0.00013 20.3 4.9 0.0002 19.7 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 KZN87165.1 - 0.0098 15.3 0.3 0.0098 15.3 0.2 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) Pyr_redox_dim PF02852.17 KZN87166.1 - 1.5e-40 137.6 0.6 4.9e-40 135.9 0.1 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KZN87166.1 - 2e-37 129.0 18.8 2.6e-36 125.4 13.0 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN87166.1 - 2e-21 76.1 10.7 2.1e-19 69.7 0.7 3.3 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN87166.1 - 1.2e-10 41.1 6.7 2.3e-10 40.1 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN87166.1 - 2.2e-09 37.2 5.8 7.8e-05 22.6 0.4 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KZN87166.1 - 1.4e-08 34.0 15.9 2.1e-07 30.1 3.9 3.5 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 KZN87166.1 - 2.1e-08 33.4 11.3 0.00046 19.2 0.1 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN87166.1 - 4.5e-08 33.4 1.5 5.4e-06 26.6 0.4 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN87166.1 - 2.2e-07 30.0 3.0 2.2e-07 30.0 2.1 3.0 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 KZN87166.1 - 7.1e-06 25.1 0.3 0.013 14.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KZN87166.1 - 2.4e-05 23.9 2.5 0.0059 16.1 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KZN87166.1 - 0.00021 19.8 1.8 0.00021 19.8 1.2 3.8 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.12 KZN87166.1 - 0.001 18.2 2.3 0.001 18.2 1.6 2.6 1 1 1 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KZN87166.1 - 0.0048 15.8 0.8 0.04 12.8 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 KZN87166.1 - 0.019 14.6 1.3 0.019 14.6 0.9 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KZN87166.1 - 0.021 13.8 8.8 0.34 9.9 0.6 3.1 3 0 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 KZN87166.1 - 0.069 13.4 2.3 0.65 10.2 0.2 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.14 KZN87166.1 - 0.091 10.9 0.9 0.47 8.5 0.0 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.12 KZN87166.1 - 1.3 9.4 5.1 5.1 7.5 1.7 3.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.9 KZN87166.1 - 5.3 5.5 7.5 1 7.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Asparaginase PF00710.15 KZN87167.1 - 3e-67 226.7 4.0 3.5e-67 226.5 2.8 1.0 1 0 0 1 1 1 1 Asparaginase HEAT_2 PF13646.1 KZN87168.1 - 6e-25 87.3 10.3 1.5e-05 25.2 0.0 5.9 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KZN87168.1 - 2.8e-17 61.1 10.0 0.17 12.0 0.0 9.2 9 0 0 9 9 9 5 HEAT repeat NACHT PF05729.7 KZN87168.1 - 3e-15 56.2 0.1 1.3e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain HEAT_EZ PF13513.1 KZN87168.1 - 2.9e-12 46.6 7.4 0.0065 16.9 0.1 7.6 6 2 1 7 7 7 3 HEAT-like repeat Cohesin_HEAT PF12765.2 KZN87168.1 - 1.6e-07 31.1 3.3 0.00016 21.5 0.0 3.4 2 1 1 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 KZN87168.1 - 6.4e-07 28.0 8.9 0.031 12.6 0.1 4.8 4 1 1 5 5 5 3 Adaptin N terminal region NB-ARC PF00931.17 KZN87168.1 - 1.1e-06 27.7 0.0 8.9e-06 24.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Vac14_Fab1_bd PF12755.2 KZN87168.1 - 3.8e-05 23.9 1.2 1.1 9.7 0.1 5.2 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region AAA_22 PF13401.1 KZN87168.1 - 0.00019 21.5 0.0 0.0019 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain TolA PF06519.6 KZN87168.1 - 0.0011 18.9 0.0 0.19 11.7 0.0 2.8 2 0 0 2 2 2 1 TolA C-terminal AAA_17 PF13207.1 KZN87168.1 - 0.0027 18.5 0.0 0.014 16.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN87168.1 - 0.003 17.7 0.0 0.011 15.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KZN87168.1 - 0.032 14.1 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KZN87168.1 - 0.036 13.4 0.3 0.15 11.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KZN87168.1 - 0.039 14.2 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KZN87168.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 KZN87168.1 - 0.052 13.2 0.3 0.16 11.6 0.1 1.9 2 0 0 2 2 1 0 NTPase AAA_16 PF13191.1 KZN87168.1 - 0.067 13.1 3.1 0.77 9.7 0.3 3.0 2 1 0 2 2 2 0 AAA ATPase domain Arm PF00514.18 KZN87168.1 - 0.078 12.8 0.7 79 3.2 0.0 4.8 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat CopD PF05425.8 KZN87169.1 - 0.24 11.6 3.2 0.51 10.5 2.1 1.7 1 1 1 2 2 2 0 Copper resistance protein D GTP_cyclohydroI PF01227.17 KZN87173.1 - 3.3e-70 234.9 0.2 4.2e-70 234.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KZN87173.1 - 0.00076 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Pribosyltran PF00156.22 KZN87174.1 - 1.4e-18 66.8 0.0 2.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 KZN87174.1 - 5.6e-14 51.7 1.7 1.8e-13 50.1 1.2 1.9 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.9 KZN87174.1 - 2.7e-08 33.5 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase UPRTase PF14681.1 KZN87174.1 - 0.0027 16.9 0.1 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.7 KZN87174.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PRTase_2 PF15609.1 KZN87174.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Aegerolysin PF06355.8 KZN87175.1 - 2.2e-30 105.2 1.7 2.6e-30 104.9 1.2 1.1 1 0 0 1 1 1 1 Aegerolysin TPR_11 PF13414.1 KZN87177.1 - 4.2e-14 51.9 2.4 1.4e-11 43.8 0.0 3.3 3 0 0 3 3 3 1 TPR repeat SET PF00856.23 KZN87177.1 - 4.5e-14 53.0 0.0 1.6e-12 47.9 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 KZN87177.1 - 2.4e-10 39.5 0.1 1.8e-06 27.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN87177.1 - 2.1e-08 33.4 0.9 0.0016 18.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN87177.1 - 2.1e-06 27.8 0.1 0.53 11.0 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN87177.1 - 3e-05 23.4 0.0 0.12 12.2 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN87177.1 - 5.3e-05 22.7 0.1 0.0038 16.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN87177.1 - 0.00011 22.7 1.7 0.16 12.6 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN87177.1 - 0.00026 21.0 1.3 0.00081 19.4 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KZN87177.1 - 0.00027 20.8 1.3 0.016 15.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KZN87177.1 - 0.0021 18.4 1.2 0.67 10.5 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN87177.1 - 0.0034 17.6 0.6 1.8 8.9 0.7 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN87177.1 - 0.012 15.4 0.1 3.1 7.7 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.1 KZN87177.1 - 0.03 13.8 0.4 0.44 9.9 0.0 2.2 1 1 1 2 2 2 0 Outer membrane lipoprotein MFS_1 PF07690.11 KZN87179.1 - 5.1e-31 107.6 39.5 6.5e-31 107.3 27.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87179.1 - 3.2e-08 32.5 15.0 3.2e-08 32.5 10.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KZN87179.1 - 1.2e-06 27.0 1.5 1.7e-06 26.5 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SKG6 PF08693.5 KZN87181.1 - 0.00026 20.2 0.9 0.00048 19.3 0.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 KZN87181.1 - 0.00094 18.8 0.3 0.0029 17.2 0.0 1.8 1 1 1 2 2 2 1 Protocadherin Herpes_gE PF02480.11 KZN87181.1 - 0.0011 17.2 0.1 0.0016 16.7 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KZN87181.1 - 0.0055 16.4 0.1 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 RCR PF12273.3 KZN87181.1 - 0.018 15.6 0.1 0.039 14.5 0.1 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FixQ PF05545.6 KZN87181.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glycophorin_A PF01102.13 KZN87181.1 - 0.057 13.1 3.5 0.12 12.1 2.4 1.5 1 1 0 1 1 1 0 Glycophorin A DUF4328 PF14219.1 KZN87181.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) EphA2_TM PF14575.1 KZN87181.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KZN87181.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain ORC6 PF05460.8 KZN87181.1 - 0.31 10.1 4.2 0.42 9.6 2.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Glyco_transf_8 PF01501.15 KZN87182.1 - 2e-10 40.4 0.1 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Sad1_UNC PF07738.8 KZN87182.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Pkinase PF00069.20 KZN87184.1 - 5.9e-12 45.2 0.0 8.8e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KZN87184.1 - 1.8e-07 31.1 0.1 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN87184.1 - 6.5e-06 25.3 0.1 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KZN87184.1 - 6.7e-05 22.0 0.0 9.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KZN87184.1 - 0.00037 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KZN87184.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PGM_PMM_II PF02879.11 KZN87185.1 - 3.3e-24 85.2 0.0 9.4e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 KZN87185.1 - 9.7e-24 83.4 0.1 2.1e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KZN87185.1 - 2.4e-15 56.5 0.2 4.9e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KZN87185.1 - 9.2e-09 35.1 0.0 3.2e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.19 KZN87186.1 - 1.3e-35 123.0 25.6 1.8e-35 122.6 17.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KZN87186.1 - 3.8e-13 49.0 0.0 8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Unstab_antitox PF09720.5 KZN87186.1 - 0.18 11.5 0.7 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative addiction module component CUE PF02845.11 KZN87187.1 - 1.1e-06 28.0 0.1 2.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 KZN87188.1 - 1.5e-27 95.2 0.6 1.8e-27 95.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 KZN87189.1 - 4e-07 29.5 2.8 7.9e-07 28.6 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KZN87189.1 - 0.09 12.8 4.9 0.23 11.5 3.4 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type ELYS PF13934.1 KZN87190.1 - 6.8e-79 264.7 0.3 8.1e-79 264.5 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 KZN87191.1 - 2.8e-78 262.1 3.6 7.1e-78 260.8 2.5 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KZN87191.1 - 4.5e-28 97.6 0.0 1.7e-27 95.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KZN87191.1 - 5.3e-11 43.0 9.7 0.0001 22.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN87191.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 KZN87191.1 - 0.00031 18.2 46.9 0.00031 18.2 32.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KZN87191.1 - 0.0011 18.1 2.0 0.0011 18.1 1.4 4.7 3 2 2 6 6 6 2 Reovirus sigma C capsid protein ATG16 PF08614.6 KZN87191.1 - 0.0027 17.5 5.5 0.0027 17.5 3.8 7.6 2 2 6 8 8 8 2 Autophagy protein 16 (ATG16) IncA PF04156.9 KZN87191.1 - 0.0051 16.4 14.9 0.0051 16.4 10.3 8.0 2 2 5 7 7 7 2 IncA protein Bacillus_HBL PF05791.6 KZN87191.1 - 3.9 6.8 50.6 0.25 10.6 1.6 6.4 5 1 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) Glyco_hydro_16 PF00722.16 KZN87193.1 - 2.4e-41 141.0 4.9 3.6e-41 140.4 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.17 KZN87194.1 - 3.3e-82 276.4 0.0 4.3e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KZN87194.1 - 2.8e-31 108.6 0.0 4.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KZN87194.1 - 1.8e-23 83.1 0.1 6.9e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KZN87194.1 - 4.5e-11 43.2 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KZN87194.1 - 0.00066 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain DUF550 PF04447.7 KZN87194.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) FMO-like PF00743.14 KZN87195.1 - 2.1e-28 98.8 0.0 1.1e-13 50.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN87195.1 - 3.8e-18 66.2 0.8 5e-17 62.6 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN87195.1 - 2.2e-08 34.0 0.5 0.00019 21.2 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KZN87195.1 - 1.5e-07 31.4 0.0 0.027 14.3 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN87195.1 - 6.7e-06 26.0 0.0 1.9e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN87195.1 - 1.4e-05 24.1 0.6 0.0019 17.2 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KZN87195.1 - 0.031 13.2 0.5 6.8 5.4 0.2 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 KZN87195.1 - 0.1 12.8 0.0 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 KZN87195.1 - 0.15 11.1 0.1 0.34 9.9 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KZN87195.1 - 0.22 9.9 0.1 0.64 8.4 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.1 KZN87196.1 - 3.7e-25 89.0 0.3 4.4e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN87196.1 - 1.2e-23 83.9 3.5 1.4e-23 83.6 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN87196.1 - 1.2e-09 38.1 2.0 1.7e-09 37.6 1.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KZN87196.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN87196.1 - 0.034 13.2 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.9 KZN87197.1 - 3.9e-36 124.6 0.7 4.9e-36 124.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KZN87198.1 - 7.9e-10 38.0 2.4 2e-09 36.7 0.9 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87198.1 - 1.2e-09 37.8 7.5 2.6e-09 36.8 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 KZN87199.1 - 3.8e-48 164.5 0.0 4.4e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PhyH PF05721.8 KZN87200.1 - 9e-13 48.7 0.0 6e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.16 KZN87201.1 - 2.9e-46 157.8 12.1 3.5e-46 157.5 8.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KZN87201.1 - 0.00063 19.4 0.1 0.0068 16.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF2665 PF11654.3 KZN87201.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Drc1-Sld2 PF11719.3 KZN87202.1 - 1.4e-117 393.4 29.9 1.6e-117 393.2 20.7 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Syntaxin PF00804.20 KZN87203.1 - 0.01 15.9 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Syntaxin COG6 PF06419.6 KZN87203.1 - 0.054 11.6 0.1 0.063 11.4 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF1593 PF07632.6 KZN87203.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) zf-RING_2 PF13639.1 KZN87204.1 - 5.3e-08 32.5 10.4 9.2e-08 31.7 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KZN87204.1 - 5e-06 26.4 10.6 8e-06 25.7 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN87204.1 - 8.9e-06 25.2 10.3 1.4e-05 24.6 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN87204.1 - 7.3e-05 22.3 6.1 0.00012 21.7 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN87204.1 - 0.0019 18.2 9.1 0.0055 16.7 6.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN87204.1 - 0.36 10.6 3.4 0.53 10.1 1.7 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KZN87204.1 - 0.76 9.3 6.4 1.6 8.3 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KZN87204.1 - 1.3 8.6 8.7 2.2 7.8 6.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2410 PF10307.4 KZN87205.1 - 3.9e-80 267.9 0.0 5.2e-80 267.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Fig1 PF12351.3 KZN87207.1 - 3.7e-58 196.4 5.6 3.7e-58 196.4 3.9 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KZN87207.1 - 1.6e-08 34.4 4.7 2.5e-08 33.7 3.3 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KZN87207.1 - 1.4e-05 24.2 6.3 1.4e-05 24.2 4.4 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF4064 PF13273.1 KZN87207.1 - 0.31 11.1 11.7 3 8.0 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) XPG_I PF00867.13 KZN87208.1 - 4.2e-26 90.8 0.1 8.1e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KZN87208.1 - 2.2e-23 82.4 0.0 1.5e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 KZN87208.1 - 0.00028 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing DUF2962 PF11176.3 KZN87209.1 - 5.2e-51 172.2 4.9 5.9e-51 172.0 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3965 PF13112.1 KZN87209.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) HTH_32 PF13565.1 KZN87209.1 - 0.84 10.4 6.6 3.2 8.6 1.4 2.4 1 1 1 2 2 2 0 Homeodomain-like domain MAM33 PF02330.11 KZN87210.1 - 1.5e-35 122.7 5.8 1.9e-35 122.4 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein FctA PF12892.2 KZN87210.1 - 0.1 13.4 0.1 0.66 10.8 0.0 2.1 2 0 0 2 2 2 0 T surface-antigen of pili Kri1 PF05178.7 KZN87210.1 - 0.27 11.5 4.5 0.21 11.8 1.5 1.9 2 0 0 2 2 2 0 KRI1-like family TBX PF12598.3 KZN87210.1 - 0.45 10.9 3.7 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 T-box transcription factor DNA_primase_S PF01896.14 KZN87211.1 - 2.9e-54 182.7 0.0 4.7e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit CDC27 PF09507.5 KZN87211.1 - 3.2 6.8 4.7 4.7 6.3 3.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Profilin PF00235.14 KZN87213.1 - 2e-17 63.4 0.0 2.3e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Profilin Sugar_tr PF00083.19 KZN87214.1 - 2.9e-74 250.3 23.9 3.5e-74 250.0 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87214.1 - 1.5e-17 63.3 51.2 2.8e-14 52.6 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 KZN87214.1 - 6.2 7.1 13.0 15 5.9 3.2 2.9 2 1 1 3 3 3 0 Divalent cation transporter Thr_synth_N PF14821.1 KZN87215.1 - 4.1e-30 103.6 0.0 3.3e-29 100.7 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KZN87215.1 - 3.7e-14 52.6 0.0 8.9e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N PF08240.7 KZN87216.1 - 2e-24 85.4 6.1 4.1e-24 84.4 4.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN87216.1 - 3.7e-16 58.8 0.0 6.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN87216.1 - 1.4e-06 29.1 0.0 2.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN87216.1 - 0.01 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adaptin_N PF01602.15 KZN87217.1 - 3.3e-148 494.3 1.9 4.3e-148 493.9 1.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KZN87217.1 - 7.3e-32 110.6 1.1 6.4e-28 97.7 0.1 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KZN87217.1 - 1.7e-20 73.0 1.5 4.6e-06 26.8 0.0 6.1 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KZN87217.1 - 2.9e-11 42.4 2.8 0.015 15.3 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KZN87217.1 - 4.7e-05 23.7 2.8 1.8 9.1 0.0 6.9 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 KZN87217.1 - 5.4e-05 22.6 1.0 0.49 9.7 0.0 4.3 3 2 2 5 5 5 2 CLASP N terminal Arm PF00514.18 KZN87217.1 - 0.0041 16.8 1.0 35 4.4 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat EntA_Immun PF08951.5 KZN87218.1 - 0.038 14.1 0.1 0.089 12.9 0.1 1.5 2 0 0 2 2 2 0 Enterocin A Immunity Vps55 PF04133.9 KZN87218.1 - 0.088 12.5 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DEK_C PF08766.6 KZN87219.1 - 0.00014 21.5 0.1 0.00039 20.1 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Evr1_Alr PF04777.8 KZN87220.1 - 3.6e-26 90.8 3.0 3.6e-26 90.8 2.1 1.7 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 KZN87220.1 - 0.075 12.8 0.0 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase Coatomer_WDAD PF04053.9 KZN87221.1 - 7.4e-152 506.1 0.0 2.8e-151 504.2 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KZN87221.1 - 2.5e-94 316.2 0.0 3.5e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KZN87221.1 - 4.3e-51 169.0 10.2 2.4e-09 36.7 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KZN87221.1 - 0.012 13.7 7.1 1.3 7.0 0.0 3.9 1 1 0 4 4 4 0 Nucleoporin Nup120/160 MIP-T3 PF10243.4 KZN87222.1 - 0.019 13.4 14.0 0.029 12.8 9.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NMU PF02070.10 KZN87222.1 - 0.54 9.8 5.4 4.9 6.7 2.2 2.8 2 0 0 2 2 2 0 Neuromedin U TBCC PF07986.7 KZN87223.1 - 8.5e-35 118.7 0.5 1.3e-34 118.1 0.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Halo_GVPC PF05465.8 KZN87223.1 - 0.32 10.9 2.0 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Pro-kuma_activ PF09286.6 KZN87224.1 - 9.8e-33 113.1 0.1 2.6e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KZN87224.1 - 1.5e-07 30.8 0.1 2.6e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Subtilase family SAC3_GANP PF03399.11 KZN87225.1 - 1.3e-22 80.3 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KZN87225.1 - 5.2e-20 71.6 0.0 7.5e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 WD40 PF00400.27 KZN87226.1 - 0.19 11.6 2.2 16 5.5 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat MFS_1 PF07690.11 KZN87227.1 - 1.1e-36 126.2 31.4 6.7e-33 113.8 16.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2453 PF10507.4 KZN87227.1 - 0.044 13.5 2.3 0.044 13.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) EHN PF06441.7 KZN87228.1 - 1.5e-38 131.1 0.0 2.5e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KZN87228.1 - 8.5e-09 35.6 0.9 1.8e-08 34.5 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN87228.1 - 5.5e-07 29.3 0.5 6.9e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF1917 PF08939.5 KZN87229.1 - 4.1e-74 249.3 0.0 4.8e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF4455 PF14643.1 KZN87229.1 - 0.16 10.5 0.2 0.25 9.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Vps51 PF08700.6 KZN87230.1 - 1.3e-27 95.4 0.0 2.9e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KZN87230.1 - 0.0085 14.5 0.2 0.011 14.2 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 KZN87230.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 ResIII PF04851.10 KZN87230.1 - 0.049 13.4 0.3 0.075 12.8 0.2 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1767 PF08585.7 KZN87231.1 - 1.6e-21 76.3 0.4 2.3e-21 75.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 KZN87232.1 - 2.4e-34 116.7 38.0 3.9e-07 29.6 0.5 12.2 9 4 6 15 15 13 11 TPR repeat TPR_14 PF13428.1 KZN87232.1 - 7.9e-27 91.3 38.4 1.6e-05 25.0 0.2 15.8 12 3 4 16 16 14 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN87232.1 - 2e-26 92.0 42.8 0.00011 22.7 0.4 12.2 11 2 2 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.23 KZN87232.1 - 1.1e-25 88.1 22.9 8.6e-05 21.9 0.0 11.9 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 KZN87232.1 - 1.8e-24 83.5 40.6 0.00013 21.6 0.1 15.3 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.1 KZN87232.1 - 8.2e-23 80.5 21.5 2.9e-05 24.3 0.4 10.6 8 3 3 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 KZN87232.1 - 1.3e-22 78.0 19.1 0.094 12.9 0.0 15.2 16 1 0 16 16 15 5 Tetratricopeptide repeat TPR_12 PF13424.1 KZN87232.1 - 6.3e-18 64.4 34.9 3e-08 33.4 1.3 10.3 10 3 4 14 14 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 KZN87232.1 - 9.1e-17 59.5 21.7 0.00019 20.9 0.0 11.7 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN87232.1 - 2.8e-12 45.4 12.2 0.002 17.7 0.1 9.2 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN87232.1 - 3.7e-12 45.8 26.7 3.1e-05 24.1 0.1 12.2 13 1 0 13 13 12 3 Tetratricopeptide repeat Apc3 PF12895.2 KZN87232.1 - 1.6e-09 37.7 18.4 9.9e-06 25.6 1.4 6.8 6 2 2 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KZN87232.1 - 1.5e-06 27.9 11.2 0.22 11.4 0.3 6.6 6 2 1 7 7 7 3 Tetratricopeptide repeat DUF2225 PF09986.4 KZN87232.1 - 0.0032 16.9 1.5 8.1 5.8 0.1 4.1 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KZN87232.1 - 0.038 13.9 19.6 0.56 10.2 0.5 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Malate_DH PF12434.3 KZN87232.1 - 0.76 9.5 5.4 8.5 6.1 0.1 3.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Cellulase PF00150.13 KZN87233.1 - 2.6e-08 33.4 5.6 3.9e-07 29.5 2.3 2.6 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KZN87233.1 - 0.008 15.3 1.7 0.62 9.1 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 KZN87233.1 - 0.049 12.9 0.4 0.094 12.0 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Xpo1 PF08389.7 KZN87234.1 - 1.9e-10 40.8 4.9 1.2e-05 25.2 0.0 4.0 4 0 0 4 4 4 2 Exportin 1-like protein HEAT_2 PF13646.1 KZN87234.1 - 0.0022 18.2 0.4 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats GRIM-19 PF06212.7 KZN87235.1 - 7.6e-23 80.6 0.3 1.5e-22 79.6 0.2 1.4 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 KZN87236.1 - 3.5e-29 101.7 0.0 4.5e-28 98.1 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 KZN87237.1 - 0 1164.1 3.8 0 1163.9 2.6 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Acetyltransf_1 PF00583.19 KZN87239.1 - 1.1e-07 31.7 0.0 2.6e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN87239.1 - 0.00083 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN87239.1 - 0.005 16.9 0.1 0.015 15.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 KZN87240.1 - 3.3e-09 36.0 0.0 7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87240.1 - 1.7e-07 30.9 9.4 3.7e-07 29.9 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MLP1_2 PF07926.7 KZN87241.1 - 0.0076 15.9 1.5 0.012 15.3 1.0 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 KZN87241.1 - 0.022 14.5 1.4 0.033 13.9 1.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit CCDC155 PF14662.1 KZN87241.1 - 0.13 11.8 0.7 0.19 11.3 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4559 PF15112.1 KZN87241.1 - 0.18 10.9 0.9 0.27 10.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Dynamin_M PF01031.15 KZN87242.1 - 3.7e-12 45.6 0.1 1.5e-11 43.6 0.0 1.9 1 1 1 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KZN87242.1 - 5.7e-10 39.2 0.0 1.7e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Dynamin family TLD PF07534.11 KZN87243.1 - 5.5e-25 87.9 0.0 1.2e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 TLD JAB PF01398.16 KZN87244.1 - 4.5e-14 52.1 0.0 1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KZN87244.1 - 7.3e-10 38.8 1.5 1.2e-09 38.1 1.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KZN87244.1 - 3.2e-05 23.4 0.0 8.5e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MIT PF04212.13 KZN87244.1 - 0.041 13.7 0.3 0.08 12.8 0.2 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RrnaAD PF00398.15 KZN87245.1 - 8.4e-07 28.2 0.0 1.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 KZN87246.1 - 1.1e-14 54.2 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87246.1 - 2.1e-05 23.7 0.0 3.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN87246.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C13 PF01650.13 KZN87247.1 - 0.005 16.1 0.0 0.0053 16.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family Polyketide_cyc2 PF10604.4 KZN87249.1 - 0.00088 19.4 9.7 0.11 12.6 6.8 2.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KZN87249.1 - 0.061 13.3 2.7 0.36 10.8 1.9 2.0 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport CRISPR_assoc PF08798.6 KZN87249.1 - 0.065 12.9 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein PLRV_ORF5 PF01690.12 KZN87249.1 - 4.2 6.4 14.8 5.7 5.9 10.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Fungal_trans_2 PF11951.3 KZN87251.1 - 5.9e-11 41.5 0.2 2e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87251.1 - 0.00018 21.3 7.1 0.00018 21.3 4.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KZN87252.1 - 7.1e-95 318.4 0.0 8.5e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Iso_dh PF00180.15 KZN87254.1 - 4.4e-69 233.0 0.0 5.3e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 KZN87254.1 - 0.1 12.6 0.2 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) FTHFS PF01268.14 KZN87255.1 - 1.2e-255 848.7 0.2 1.7e-255 848.3 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KZN87255.1 - 3.4e-67 224.5 0.9 8.1e-67 223.3 0.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KZN87255.1 - 2.2e-34 117.9 0.6 4.8e-34 116.8 0.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KZN87255.1 - 0.022 14.2 0.3 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 KZN87256.1 - 1.1e-32 110.6 3.1 6.7e-11 41.6 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Gmad1 PF10647.4 KZN87256.1 - 5.9e-06 25.8 0.3 1.2e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 KZN87256.1 - 1.9e-05 24.2 0.9 3.6e-05 23.3 0.6 1.6 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KZN87256.1 - 0.0011 17.2 0.1 0.0016 16.6 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 MBF1 PF08523.5 KZN87257.1 - 1.2e-23 82.9 0.9 2.1e-23 82.1 0.7 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KZN87257.1 - 1e-08 34.8 0.1 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KZN87257.1 - 0.00023 21.2 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KZN87257.1 - 0.00068 19.6 0.1 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain SH3_1 PF00018.23 KZN87258.1 - 4.9e-15 54.6 0.0 7.6e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN87258.1 - 7.4e-14 51.0 0.0 1.8e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KZN87258.1 - 2.4e-09 36.5 0.0 3.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 KZN87258.1 - 8.9 4.4 15.0 9.8 4.2 10.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ank_2 PF12796.2 KZN87259.1 - 1.1e-37 128.1 6.2 3.8e-16 59.2 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87259.1 - 4.2e-29 98.8 8.9 5.6e-07 29.0 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KZN87259.1 - 8.9e-27 92.5 8.5 7e-11 42.0 0.0 5.5 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87259.1 - 8.8e-26 89.8 2.6 2.1e-08 34.4 0.0 5.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87259.1 - 4.6e-15 54.2 4.6 0.077 13.2 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat AIM24 PF01987.12 KZN87260.1 - 5.9e-55 186.0 0.0 7.5e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.12 KZN87261.1 - 3.6e-43 146.1 0.2 5.3e-43 145.6 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KZN87261.1 - 0.12 12.6 0.5 0.38 11.0 0.4 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 KZN87261.1 - 1.9 8.7 7.1 1.1 9.4 0.2 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.17 KZN87264.1 - 8.1e-20 70.2 0.0 1.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN87264.1 - 5e-14 52.0 0.0 6.6e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN87264.1 - 7.9e-10 38.4 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN87264.1 - 0.04 13.7 0.1 0.074 12.8 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif ChaC PF04752.7 KZN87265.1 - 2e-39 135.3 0.2 2.8e-38 131.6 0.2 2.0 1 1 0 1 1 1 1 ChaC-like protein DUF3433 PF11915.3 KZN87266.1 - 9.8e-47 157.0 6.1 2.3e-24 85.3 0.2 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) adh_short PF00106.20 KZN87267.1 - 2e-13 50.6 0.0 5.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN87267.1 - 1.9e-07 30.8 0.0 5.8e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Ank_2 PF12796.2 KZN87268.1 - 5.3e-100 327.9 12.0 2.9e-18 65.9 0.1 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87268.1 - 1.1e-52 173.3 13.4 0.0001 21.9 0.1 11.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KZN87268.1 - 7.9e-42 140.9 7.3 8.8e-07 29.2 0.0 10.3 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87268.1 - 1.8e-33 111.2 1.2 0.055 13.7 0.0 11.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KZN87268.1 - 5.1e-27 93.2 17.1 7.4e-07 29.2 0.3 6.8 3 1 2 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 KZN87268.1 - 1.8e-07 31.0 0.0 4.3e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF4564 PF15169.1 KZN87268.1 - 0.0036 17.0 0.4 3.7 7.2 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4564) AAA_22 PF13401.1 KZN87268.1 - 0.0099 16.0 0.1 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ING PF12998.2 KZN87268.1 - 1.5 9.1 4.7 0.92 9.8 0.1 2.8 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding EF-hand_1 PF00036.27 KZN87269.1 - 9.9e-22 74.5 0.1 4e-08 31.9 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KZN87269.1 - 8.1e-19 65.7 1.0 0.00027 20.5 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KZN87269.1 - 8.4e-19 67.4 0.1 8.9e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KZN87269.1 - 4.3e-18 64.6 0.8 1e-08 34.6 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KZN87269.1 - 2.9e-14 51.6 2.2 9.1e-05 21.6 0.0 3.6 3 0 0 3 3 3 3 EF hand F-box-like PF12937.2 KZN87270.1 - 0.0017 18.0 6.8 0.028 14.1 4.3 3.0 2 1 0 2 2 2 1 F-box-like Cytokin_check_N PF10407.4 KZN87270.1 - 0.0022 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus MFS_1 PF07690.11 KZN87272.1 - 3.7e-50 170.6 59.1 1.2e-48 165.6 40.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN87272.1 - 1.7e-22 79.3 18.7 2.8e-22 78.6 13.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN87272.1 - 9.6e-13 47.4 15.3 9.6e-13 47.4 10.6 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KZN87272.1 - 4.5e-05 22.0 6.3 4.5e-05 22.0 4.3 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 KZN87272.1 - 0.0022 16.1 19.0 0.016 13.3 1.4 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KZN87272.1 - 0.069 12.9 6.9 0.27 11.0 0.3 3.1 2 1 1 3 3 3 0 MFS_1 like family zf-C2H2_4 PF13894.1 KZN87274.1 - 1.4e-05 25.0 3.0 0.012 15.9 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN87274.1 - 0.00037 20.6 14.2 0.0091 16.2 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN87274.1 - 0.0061 16.4 2.8 0.0074 16.1 0.9 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KZN87274.1 - 0.023 14.8 1.4 0.023 14.8 1.0 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KZN87274.1 - 0.027 14.7 2.9 0.032 14.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 KZN87274.1 - 0.96 9.8 9.9 1 9.7 0.1 3.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain MoCF_biosynth PF00994.19 KZN87275.1 - 4.6e-22 77.9 0.0 6.4e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 KZN87275.1 - 1.4e-08 34.3 0.0 2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) B12-binding PF02310.14 KZN87275.1 - 0.032 14.1 0.0 0.075 12.9 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain NTP_transf_3 PF12804.2 KZN87276.1 - 2.2e-21 76.5 0.0 3.2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Molybdopterin PF00384.17 KZN87277.1 - 8.6e-66 222.4 0.0 1.2e-65 221.9 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 KZN87277.1 - 4.2e-30 103.7 0.0 1.2e-29 102.3 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 KZN87277.1 - 7.3e-13 48.1 1.3 1.7e-12 46.9 0.4 2.1 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain zf-C2H2 PF00096.21 KZN87278.1 - 2.1e-06 27.7 8.4 0.01 16.1 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87278.1 - 0.0023 18.1 9.5 0.15 12.4 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN87278.1 - 0.017 15.3 0.7 0.017 15.3 0.5 2.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.7 KZN87278.1 - 0.036 14.2 2.0 0.085 12.9 0.2 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KZN87278.1 - 0.44 10.8 10.0 0.53 10.6 1.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain G6PD_C PF02781.11 KZN87279.1 - 1.7e-137 457.1 0.0 2.9e-137 456.3 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KZN87279.1 - 5.4e-66 222.3 0.1 8.9e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 KZN87279.1 - 0.06 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) MFS_2 PF13347.1 KZN87280.1 - 1.5e-13 49.9 16.1 1.7e-13 49.8 10.1 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 KZN87280.1 - 0.015 15.1 4.9 0.051 13.3 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family DJ-1_PfpI PF01965.19 KZN87282.1 - 2.9e-24 85.2 0.1 4.6e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KZN87282.1 - 2.6e-19 68.4 0.2 6.9e-19 67.0 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KZN87282.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase Peptidase_C26 PF07722.8 KZN87282.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 DUF1708 PF08101.6 KZN87283.1 - 3.1e-151 503.9 0.0 4.2e-151 503.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KZN87283.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain SRF-TF PF00319.13 KZN87284.1 - 3.2e-23 80.6 0.1 4.8e-23 80.1 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GFA PF04828.9 KZN87285.1 - 7.6e-24 83.4 0.1 9.8e-24 83.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Elf1 PF05129.8 KZN87285.1 - 0.17 11.5 1.2 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Nudix_N_2 PF14803.1 KZN87285.1 - 1.1 8.9 0.1 1.1 8.9 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal SIMPL PF04402.9 KZN87286.1 - 1.5e-26 93.5 0.0 1.7e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Aminotran_1_2 PF00155.16 KZN87287.1 - 1.9e-41 142.2 0.0 2.3e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cu_amine_oxidN2 PF02727.11 KZN87287.1 - 0.04 14.0 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain Aminotran_3 PF00202.16 KZN87287.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF2670 PF10875.3 KZN87287.1 - 0.14 12.1 0.1 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Beta_elim_lyase PF01212.16 KZN87287.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 1 0 1 1 1 0 Beta-eliminating lyase Ank_2 PF12796.2 KZN87288.1 - 2e-71 236.3 12.6 8.3e-18 64.5 0.1 5.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87288.1 - 9.2e-55 179.8 13.3 2.3e-07 30.2 0.0 10.9 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 KZN87288.1 - 4.6e-39 128.5 5.8 1e-06 28.4 0.0 11.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KZN87288.1 - 6.3e-36 121.6 9.5 4.8e-08 32.9 0.2 9.4 1 1 9 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87288.1 - 2.9e-32 110.4 2.8 3.4e-08 33.7 0.1 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 KZN87288.1 - 0.0026 17.4 0.0 0.0081 15.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 KZN87288.1 - 0.027 13.9 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KZN87288.1 - 0.049 13.6 2.1 0.78 9.6 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain PAPS_reduct PF01507.14 KZN87289.1 - 1.3e-42 145.6 0.2 2.7e-42 144.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 KZN87290.1 - 1.3e-16 61.3 0.0 1.9e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN87290.1 - 9.1e-12 45.8 0.2 4.3e-10 40.3 1.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN87290.1 - 3.5e-11 43.1 0.1 8.9e-09 35.2 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN87290.1 - 2.7e-07 30.9 0.0 5.3e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KZN87290.1 - 0.00081 18.6 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.7 KZN87290.1 - 0.023 13.7 0.1 0.035 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Radical_SAM PF04055.16 KZN87291.1 - 1.7e-14 54.3 0.0 2.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.27 KZN87293.1 - 1.7e-12 46.6 11.5 1.1e-06 28.3 0.2 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KZN87293.1 - 0.00073 19.0 1.0 0.012 15.1 0.2 2.6 2 1 1 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 KZN87293.1 - 0.025 14.8 5.1 1.3 9.4 0.0 3.9 3 1 1 4 4 4 0 PQQ-like domain TBPIP PF07106.8 KZN87293.1 - 0.066 12.7 7.4 0.1 12.1 5.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 KZN87293.1 - 0.15 11.2 9.9 0.22 10.7 6.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Gon7 PF08738.5 KZN87293.1 - 1.2 9.1 7.0 3 7.8 4.9 1.6 1 1 0 1 1 1 0 Gon7 family ADIP PF11559.3 KZN87293.1 - 4.5 7.1 12.8 7.6 6.4 8.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GRP PF07172.6 KZN87294.1 - 0.00022 21.6 1.5 0.00027 21.3 1.1 1.1 1 0 0 1 1 1 1 Glycine rich protein family DUF2763 PF10961.3 KZN87294.1 - 0.0015 18.9 13.9 0.016 15.5 9.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) eIF-4B PF06273.6 KZN87294.1 - 4.3 5.9 6.5 4.9 5.7 4.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B TP_methylase PF00590.15 KZN87295.1 - 1.5e-45 155.4 0.1 2.5e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KZN87295.1 - 2.3e-14 53.4 0.0 4.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KZN87295.1 - 8.6e-10 37.7 0.0 3e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal PCI PF01399.22 KZN87296.1 - 1.3e-21 76.9 0.0 3.9e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain Ku_PK_bind PF08785.6 KZN87296.1 - 0.019 14.8 0.1 0.096 12.5 0.1 2.3 1 0 0 1 1 1 0 Ku C terminal domain like DASH_Dad3 PF08656.5 KZN87296.1 - 0.18 11.4 2.6 0.43 10.2 0.5 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 FTA4 PF13093.1 KZN87296.1 - 6.1 6.2 12.1 1.6 8.0 5.6 2.1 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FSH1 PF03959.8 KZN87297.1 - 1.4e-72 243.5 0.0 1.7e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KZN87297.1 - 1.4e-08 34.5 0.7 2.1e-08 34.0 0.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN87297.1 - 1.5e-07 31.5 1.1 1.8e-06 27.9 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KZN87297.1 - 0.00048 19.6 0.1 2 7.8 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 KZN87297.1 - 0.0022 17.2 0.1 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Ribosomal_S27e PF01667.12 KZN87299.1 - 5.7e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KZN87299.1 - 0.0043 16.8 1.2 0.005 16.6 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 KZN87299.1 - 0.11 12.0 0.8 0.2 11.1 0.6 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 KZN87300.1 - 2.1e-12 47.2 4.0 2.1e-12 47.2 2.8 3.1 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.8 KZN87301.1 - 3.2e-38 129.8 4.8 2.7e-27 94.7 0.0 2.9 3 0 0 3 3 3 2 NIPSNAP Pyridox_oxidase PF01243.15 KZN87302.1 - 4.7e-13 48.9 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 KZN87302.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Colicin_C PF12106.3 KZN87302.1 - 1.9 8.1 6.0 0.69 9.5 0.1 2.8 3 0 0 3 3 3 0 Colicin C terminal ribonuclease domain BPL_LplA_LipB PF03099.14 KZN87303.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 KZN87304.1 - 8.4e-19 67.5 0.0 9.7e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN87304.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein PCI PF01399.22 KZN87305.1 - 6.7e-20 71.3 0.1 1.8e-19 69.9 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KZN87305.1 - 3.7e-06 26.7 0.1 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ipi1_N PF12333.3 KZN87305.1 - 0.034 14.1 0.4 0.98 9.4 0.0 3.0 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Peptidase_C65 PF10275.4 KZN87306.1 - 5.6e-63 212.5 0.0 7e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF4066 PF13278.1 KZN87307.1 - 2.3e-15 56.2 0.0 3.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KZN87307.1 - 8.9e-13 47.9 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KZN87307.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Sugar_tr PF00083.19 KZN87308.1 - 1.2e-119 399.8 18.3 2e-119 399.1 12.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87308.1 - 2.2e-23 82.5 60.4 4.3e-18 65.1 21.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN87308.1 - 0.00013 20.3 1.8 0.00013 20.3 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KZN87309.1 - 7e-33 113.6 0.2 1.3e-32 112.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87309.1 - 3e-10 39.8 10.8 5.1e-10 39.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KZN87309.1 - 3.7e-05 23.5 0.1 7.7e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain DUF2348 PF09807.4 KZN87310.1 - 4.5e-10 39.0 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KZN87310.1 - 0.02 14.0 0.0 0.05 12.7 0.0 1.6 2 0 0 2 2 2 0 KaiC Slu7 PF11708.3 KZN87311.1 - 3.2e-78 262.7 13.7 3.2e-78 262.7 9.5 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KZN87311.1 - 0.021 14.4 0.7 0.042 13.5 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4526 PF15029.1 KZN87311.1 - 3.6 7.0 5.2 1.1 8.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4526) DNA_pol_B PF00136.16 KZN87312.1 - 4.2e-94 315.9 0.0 6e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KZN87312.1 - 1.5e-23 83.1 0.0 4e-11 42.3 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KZN87312.1 - 1.7e-20 72.7 2.0 4.8e-20 71.3 1.4 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RdRP PF05183.7 KZN87313.1 - 1.7e-184 614.7 0.1 6.4e-184 612.8 0.0 1.8 2 0 0 2 2 2 1 RNA dependent RNA polymerase RRM_1 PF00076.17 KZN87313.1 - 0.00012 21.5 0.0 0.0004 19.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMF_DNA_bd PF12329.3 KZN87314.1 - 0.00092 18.9 10.1 0.00092 18.9 7.0 6.0 3 1 2 6 6 6 3 TATA element modulatory factor 1 DNA binding FAD-oxidase_C PF02913.14 KZN87315.1 - 4.8e-61 206.2 0.0 6.4e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KZN87315.1 - 2.1e-36 124.4 0.0 4.7e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KZN87315.1 - 0.087 11.2 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Semialdhyde_dhC PF02774.13 KZN87316.1 - 7.2e-35 120.5 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KZN87316.1 - 4.5e-30 104.4 0.0 1.2e-29 103.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KZN87316.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S4e PF00900.15 KZN87317.1 - 8.6e-34 115.0 0.2 1.7e-33 114.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KZN87317.1 - 2.1e-16 59.4 3.7 4.3e-16 58.4 2.5 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KZN87317.1 - 6.8e-07 28.6 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KZN87317.1 - 0.0055 16.3 1.4 0.0055 16.3 1.0 3.2 4 0 0 4 4 4 1 KOW motif RasGEF PF00617.14 KZN87318.1 - 3.2e-06 27.0 0.0 1.4e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain Cdc6_C PF09079.6 KZN87318.1 - 0.13 11.9 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 CDC6, C terminal Myb_DNA-bind_6 PF13921.1 KZN87320.1 - 5.7e-15 55.1 0.0 1.9e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN87320.1 - 1.7e-12 47.1 0.4 1.2e-05 25.2 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 KZN87321.1 - 5.6e-27 93.7 0.2 6.8e-27 93.5 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 KZN87321.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus GFA PF04828.9 KZN87322.1 - 3.5e-12 46.0 5.3 2.9e-09 36.7 0.0 2.5 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KZN87322.1 - 0.22 11.8 5.2 1.5 9.1 0.1 3.3 2 1 1 3 3 3 0 Restriction alleviation protein Lar NOB1_Zn_bind PF08772.6 KZN87322.1 - 3.2 7.6 6.7 14 5.5 0.2 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-B_box PF00643.19 KZN87322.1 - 9.6 6.1 7.4 52 3.8 0.4 3.1 3 0 0 3 3 3 0 B-box zinc finger WD40 PF00400.27 KZN87323.1 - 3.7e-20 70.9 15.7 2e-05 24.2 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KZN87323.1 - 2.2e-05 22.9 1.3 0.3 9.3 0.0 3.9 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 KZN87323.1 - 0.0026 17.9 0.5 1.4 9.3 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain Nucleoporin_N PF08801.6 KZN87323.1 - 0.052 12.2 0.1 2.1 7.0 0.1 2.6 2 1 0 2 2 2 0 Nup133 N terminal like PPARgamma_N PF12577.3 KZN87323.1 - 0.12 12.7 4.6 12 6.2 0.1 3.4 2 1 0 2 2 2 0 PPAR gamma N-terminal region SecE PF00584.15 KZN87324.1 - 9.8e-13 47.4 0.0 1.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 KZN87325.1 - 3.4e-08 33.3 0.0 6.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN87325.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN87325.1 - 0.09 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-DHHC PF01529.15 KZN87326.1 - 0.0086 15.4 3.0 0.013 14.8 2.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Abhydrolase_6 PF12697.2 KZN87327.1 - 1.2e-06 28.6 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN87327.1 - 1.8e-05 24.5 0.0 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KZN87327.1 - 0.0013 17.3 0.0 0.61 8.5 0.0 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KZN87327.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Tmemb_cc2 PF10267.4 KZN87329.1 - 0.092 11.3 0.2 0.089 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Mito_carr PF00153.22 KZN87330.1 - 2.1e-77 254.9 2.8 1.2e-25 89.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 KZN87330.1 - 0.0031 16.9 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) Ribosomal_L21e PF01157.13 KZN87331.1 - 1e-39 134.3 4.0 1e-39 134.3 2.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e CEP1-DNA_bind PF09287.5 KZN87331.1 - 0.052 12.9 0.2 0.061 12.7 0.2 1.2 1 0 0 1 1 1 0 CEP-1, DNA binding Ribosomal_S4 PF00163.14 KZN87332.1 - 5.8e-29 100.3 0.5 9.6e-29 99.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KZN87332.1 - 6.4e-13 47.9 0.7 6.4e-13 47.9 0.5 2.3 3 0 0 3 3 3 1 S4 domain FimP PF09766.4 KZN87333.1 - 0.023 13.7 5.9 0.032 13.3 4.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein Baculo_PEP_C PF04513.7 KZN87333.1 - 0.039 13.7 1.2 0.41 10.4 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KZN87333.1 - 0.045 13.6 10.5 0.11 12.4 7.3 1.7 1 1 0 1 1 1 0 Tropomyosin like LpxC PF03331.8 KZN87333.1 - 0.083 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Spc7 PF08317.6 KZN87333.1 - 0.085 11.4 5.6 0.23 10.0 0.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.7 KZN87333.1 - 0.17 12.0 9.1 2.5 8.3 1.2 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Usp PF00582.21 KZN87333.1 - 0.18 11.9 3.9 3.8 7.6 0.6 2.5 2 1 0 2 2 2 0 Universal stress protein family Prefoldin PF02996.12 KZN87333.1 - 0.35 10.5 7.8 0.15 11.7 0.7 3.1 2 2 1 3 3 3 0 Prefoldin subunit CENP-F_leu_zip PF10473.4 KZN87333.1 - 0.38 10.5 13.6 0.097 12.5 2.7 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD PF00529.15 KZN87333.1 - 0.57 9.4 14.4 3.8 6.7 6.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Med9 PF07544.8 KZN87333.1 - 1.1 9.0 6.2 1.3 8.8 1.0 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KZN87333.1 - 1.2 8.6 15.0 0.22 11.0 1.8 2.4 1 1 1 2 2 2 0 IncA protein ISG65-75 PF11727.3 KZN87333.1 - 1.4 7.9 7.1 0.16 10.9 1.1 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein Mod_r PF07200.8 KZN87333.1 - 1.6 8.5 10.4 0.19 11.6 2.7 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TBPIP PF07106.8 KZN87333.1 - 2 7.9 12.8 0.17 11.4 2.0 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KZN87333.1 - 2.6 8.4 9.0 4.8 7.5 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KZN87333.1 - 3.9 7.2 11.4 0.68 9.7 1.3 3.4 2 2 1 3 3 3 0 Prefoldin subunit Atg14 PF10186.4 KZN87333.1 - 6.5 5.5 12.4 0.84 8.5 1.4 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MIP-T3 PF10243.4 KZN87334.1 - 0.15 10.5 32.8 0.22 9.9 22.7 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DOPA_dioxygen PF08883.6 KZN87335.1 - 9.1e-32 109.2 0.0 1.2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF946 PF06101.6 KZN87336.1 - 8.6e-08 30.6 0.4 0.00018 19.6 0.1 2.3 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 KZN87336.1 - 0.071 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Septin PF00735.13 KZN87337.1 - 2.7e-34 118.4 0.0 1.1e-13 50.8 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 KZN87337.1 - 0.00021 21.2 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KZN87337.1 - 0.0086 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 KZN87337.1 - 0.013 15.7 0.3 0.053 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KZN87337.1 - 0.034 14.6 0.0 0.099 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KZN87337.1 - 0.039 13.7 0.5 0.25 11.1 0.0 2.4 2 1 1 3 3 3 0 Dynamin family Annexin PF00191.15 KZN87338.1 - 4.5e-15 55.2 8.0 5e-06 26.3 0.0 4.7 5 0 0 5 5 5 4 Annexin DUF2172 PF09940.4 KZN87339.1 - 0.16 10.3 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) DUF1793 PF08760.6 KZN87340.1 - 1.9e-66 223.1 1.9 2.9e-66 222.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Peptidase_M20 PF01546.23 KZN87341.1 - 1.6e-25 89.7 0.0 2.5e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN87341.1 - 5.2e-10 39.0 0.0 2e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KZN87341.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 WSC PF01822.14 KZN87342.1 - 3.2e-17 62.2 11.8 6.6e-17 61.2 8.2 1.5 1 0 0 1 1 1 1 WSC domain DUF1399 PF07173.7 KZN87343.1 - 1.3e-18 67.5 0.0 3.2e-15 56.6 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Ribosomal_L31e PF01198.14 KZN87343.1 - 0.084 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L31e MARVEL PF01284.18 KZN87344.1 - 0.00016 21.5 12.6 0.0002 21.1 8.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1230 PF06799.6 KZN87344.1 - 0.17 11.7 0.7 0.32 10.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) AMP-binding PF00501.23 KZN87345.1 - 1.7e-73 247.3 0.0 2.3e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KZN87345.1 - 2.9e-57 193.4 0.0 4.9e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KZN87345.1 - 6.4e-11 42.1 0.0 2.6e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN87345.1 - 1.2e-08 35.0 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN87345.1 - 3.5e-07 29.2 0.0 8.3e-07 27.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KZN87345.1 - 9.7e-06 26.4 0.0 2.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 KZN87345.1 - 0.004 16.1 0.0 0.0074 15.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.27 KZN87346.1 - 1.6e-56 186.2 21.6 1.2e-10 40.8 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KZN87346.1 - 5.5e-06 25.3 3.1 0.088 11.5 0.0 4.7 1 1 0 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KZN87346.1 - 2.1e-05 22.8 9.7 0.16 10.0 0.1 4.8 3 3 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KZN87346.1 - 0.0031 17.0 0.1 3.9 6.8 0.0 2.9 3 1 0 3 3 3 2 PQQ-like domain Myb_DNA-bind_6 PF13921.1 KZN87348.1 - 1e-06 28.7 0.0 3.3e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN87348.1 - 0.00034 20.5 0.1 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KZN87348.1 - 0.14 12.2 4.5 0.54 10.4 1.7 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain UPF0016 PF01169.14 KZN87349.1 - 2.4e-42 142.9 24.8 7.8e-22 77.2 5.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 KZN87349.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) MFS_1 PF07690.11 KZN87350.1 - 6e-36 123.8 24.9 6e-36 123.8 17.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87350.1 - 1.4e-14 53.5 5.1 1.4e-14 53.5 3.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter FAA_hydrolase PF01557.13 KZN87351.1 - 2.3e-47 161.2 0.0 3.3e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cupin_2 PF07883.6 KZN87352.1 - 7.1e-27 92.7 0.7 2.9e-16 58.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KZN87352.1 - 6.1e-06 25.9 3.6 0.0039 16.8 0.4 2.5 1 1 1 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 KZN87352.1 - 3.6e-05 23.0 0.0 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KZN87352.1 - 0.00091 18.6 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 2 Cupin CENP-C_C PF11699.3 KZN87352.1 - 0.0039 17.1 0.0 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.9 KZN87352.1 - 0.012 15.5 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family Fungal_trans PF04082.13 KZN87353.1 - 2.8e-29 101.7 0.0 5.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87353.1 - 1e-09 38.1 6.3 2.1e-09 37.1 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KZN87354.1 - 1.8e-23 82.5 0.1 2.6e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN87354.1 - 8.5e-22 76.9 2.2 1.6e-21 76.0 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN87354.1 - 2.9e-08 34.6 0.1 4.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2_3 PF13878.1 KZN87354.1 - 0.0087 15.6 0.8 0.019 14.5 0.5 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Amidohydro_1 PF01979.15 KZN87354.1 - 0.19 11.3 1.0 13 5.2 0.2 2.4 2 1 1 3 3 3 0 Amidohydrolase family Aldedh PF00171.17 KZN87355.1 - 2.5e-128 428.3 0.0 3.1e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SnoaL_2 PF12680.2 KZN87356.1 - 1.3e-07 31.9 0.1 1.6e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.1 KZN87357.1 - 3e-26 92.6 0.0 3.8e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN87357.1 - 4.7e-18 65.6 0.1 6.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN87357.1 - 1.9e-09 37.4 0.1 4.8e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KZN87357.1 - 0.089 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 KZN87358.1 - 1.3e-23 83.3 25.2 1.3e-23 83.3 17.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87358.1 - 0.00023 19.8 29.0 0.0013 17.4 20.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter HATPase_c PF02518.21 KZN87359.1 - 1e-20 73.5 0.0 1.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN87359.1 - 8.2e-20 70.8 0.8 4.2e-19 68.5 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KZN87359.1 - 7.3e-14 51.5 0.0 2.3e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Amidohydro_2 PF04909.9 KZN87360.1 - 3.1e-24 86.0 0.5 4.9e-24 85.3 0.1 1.5 2 0 0 2 2 2 1 Amidohydrolase Aldedh PF00171.17 KZN87361.1 - 1.2e-151 505.1 0.3 1.4e-151 504.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DMRL_synthase PF00885.14 KZN87361.1 - 0.082 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase ADH_zinc_N PF00107.21 KZN87362.1 - 1.9e-28 98.6 0.1 2.9e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN87362.1 - 8.3e-13 49.3 0.7 2.2e-12 47.9 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN87362.1 - 2.7e-11 43.1 0.5 1.5e-10 40.8 0.0 2.4 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CPSase_L_chain PF00289.17 KZN87362.1 - 0.024 14.7 0.1 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DUF1338 PF07063.8 KZN87363.1 - 1.6e-74 250.6 0.0 1.9e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.13 KZN87364.1 - 1.5e-13 50.2 0.1 2.7e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87364.1 - 2.3e-10 40.2 9.7 2.3e-10 40.2 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN87364.1 - 0.019 13.5 2.0 0.041 12.4 0.0 2.2 3 0 0 3 3 3 0 Fungal specific transcription factor domain DUF2917 PF11142.3 KZN87364.1 - 0.055 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Rep_fac-A_C PF08646.5 KZN87364.1 - 0.22 11.1 4.7 0.38 10.4 3.3 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Amidohydro_2 PF04909.9 KZN87365.1 - 7.6e-47 160.1 0.0 8.9e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Aldedh PF00171.17 KZN87366.1 - 1e-143 479.0 0.0 1.2e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuc_L-PSP PF01042.16 KZN87367.1 - 3.7e-19 68.6 0.1 7.4e-19 67.6 0.1 1.5 1 1 0 1 1 1 1 Endoribonuclease L-PSP Sulfatase PF00884.18 KZN87368.1 - 1.2e-77 261.2 0.0 1.5e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KZN87368.1 - 0.0025 16.2 0.0 0.0038 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KZN87368.1 - 0.014 14.7 0.1 0.034 13.4 0.1 1.7 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KZN87368.1 - 0.072 13.3 0.5 2.4 8.4 0.3 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase AA_permease PF00324.16 KZN87369.1 - 3.7e-81 272.8 31.6 4.1e-81 272.7 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN87369.1 - 1.1e-25 90.1 32.1 1.3e-25 89.8 22.2 1.0 1 0 0 1 1 1 1 Amino acid permease Phtf-FEM1B_bdg PF12129.3 KZN87369.1 - 0.14 11.4 7.1 1.2 8.4 2.3 2.2 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor AA_permease PF00324.16 KZN87370.1 - 6.1e-21 74.3 11.4 7.1e-21 74.0 7.9 1.0 1 0 0 1 1 1 1 Amino acid permease 7TMR-DISM_7TM PF07695.6 KZN87371.1 - 0.0021 17.7 13.9 0.0052 16.4 4.7 2.2 2 0 0 2 2 2 2 7TM diverse intracellular signalling FAD_binding_4 PF01565.18 KZN87372.1 - 9.7e-16 57.4 3.4 1.8e-15 56.6 2.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN87372.1 - 7.9e-10 38.4 0.1 2.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_4 PF07993.7 KZN87373.1 - 2.2e-39 134.8 0.0 3.3e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN87373.1 - 9e-31 106.6 0.0 2.4e-30 105.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KZN87373.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN87373.1 - 0.00014 20.7 0.0 0.00031 19.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN87373.1 - 0.00086 19.3 0.0 0.0049 16.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN87373.1 - 0.0024 17.8 0.2 0.0064 16.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KZN87373.1 - 0.0065 15.3 0.0 0.075 11.9 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 KZN87373.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site UvrC_HhH_N PF08459.6 KZN87373.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NmrA PF05368.8 KZN87373.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family KR PF08659.5 KZN87373.1 - 0.1 12.2 0.1 0.3 10.7 0.1 1.7 1 1 0 1 1 1 0 KR domain Glyco_hydro_18 PF00704.23 KZN87374.1 - 3e-50 171.6 1.9 4.6e-49 167.7 1.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KZN87374.1 - 2e-05 24.4 20.6 4.1e-05 23.4 14.3 1.5 1 0 0 1 1 1 1 Chitin recognition protein GPI2 PF06432.6 KZN87375.1 - 1.6e-125 418.0 3.2 1.9e-125 417.8 2.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Yip1 PF04893.12 KZN87375.1 - 0.0075 15.7 3.5 0.0075 15.7 2.4 2.8 3 0 0 3 3 3 1 Yip1 domain MRI PF15325.1 KZN87376.1 - 6.1 7.8 9.0 0.78 10.7 2.3 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Fumble PF03630.9 KZN87377.1 - 7.8e-136 452.4 0.2 5.6e-135 449.5 0.1 1.9 1 1 0 1 1 1 1 Fumble DEAD PF00270.24 KZN87378.1 - 1.3e-42 145.1 0.0 5.7e-42 143.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN87378.1 - 3.2e-20 71.7 0.8 5.9e-20 70.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KZN87378.1 - 2.5e-06 26.5 0.0 3.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Med3 PF11593.3 KZN87378.1 - 0.015 14.5 1.8 0.027 13.7 1.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ResIII PF04851.10 KZN87378.1 - 0.035 13.9 0.2 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2413 PF10310.4 KZN87378.1 - 2.2 7.0 14.7 3.3 6.4 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Polysacc_deac_1 PF01522.16 KZN87379.1 - 5.3e-18 64.8 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fringe PF02434.11 KZN87380.1 - 3.5e-09 36.2 0.0 5.9e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KZN87380.1 - 0.022 14.4 1.5 0.045 13.4 1.0 1.5 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.7 KZN87380.1 - 0.054 12.9 0.8 0.19 11.1 0.2 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DFP PF04127.10 KZN87381.1 - 8.5e-15 54.8 0.0 1.7e-05 24.5 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Abhydrolase_3 PF07859.8 KZN87383.1 - 2.5e-41 141.5 0.0 3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN87383.1 - 1.8e-06 27.3 0.0 6.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KZN87383.1 - 4.8e-06 26.6 1.3 8.9e-06 25.7 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN87383.1 - 0.0001 22.0 0.0 0.00029 20.6 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KZN87383.1 - 0.00027 20.3 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 KZN87383.1 - 0.00087 17.8 0.0 0.011 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 KZN87383.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.15 KZN87383.1 - 0.012 15.0 0.0 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Chlorophyllase2 PF12740.2 KZN87383.1 - 0.022 13.6 0.0 0.05 12.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KZN87383.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KZN87383.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2368 PF10166.4 KZN87384.1 - 5.7 6.5 16.0 0.53 9.9 3.9 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) CENP-O PF09496.5 KZN87385.1 - 3.8e-28 97.5 0.0 6e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.2 KZN87386.1 - 8.1e-147 490.0 22.4 3.9e-75 253.4 6.8 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Yae1_N PF09811.4 KZN87389.1 - 1.4e-10 40.5 1.0 3e-10 39.4 0.1 2.0 1 1 1 2 2 2 1 Essential protein Yae1, N terminal RNase_T PF00929.19 KZN87392.1 - 8.3e-12 45.6 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease zf-C2H2 PF00096.21 KZN87392.1 - 5.2e-05 23.3 1.2 0.084 13.2 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87392.1 - 0.00058 20.0 0.7 0.48 10.8 0.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TFIIB PF13453.1 KZN87392.1 - 0.0007 18.7 0.5 0.0017 17.5 0.4 1.6 1 0 0 1 1 1 1 Transcription factor zinc-finger zf-Di19 PF05605.7 KZN87392.1 - 0.041 14.0 3.2 0.25 11.5 1.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pribosyl_synth PF14572.1 KZN87392.1 - 0.056 13.1 0.9 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain zf-C2H2_6 PF13912.1 KZN87392.1 - 0.088 12.7 0.4 5.9 6.9 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M20 PF01546.23 KZN87393.1 - 1.1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN87393.1 - 8e-05 22.3 0.0 0.00075 19.2 0.0 2.4 2 2 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KZN87394.1 - 9.8e-16 57.3 3.1 1.7e-08 33.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CMD PF02627.15 KZN87395.1 - 1.2e-09 37.8 0.0 4.2e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 Carboxymuconolactone decarboxylase family Lactonase PF10282.4 KZN87396.1 - 1.5e-18 66.9 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.2 KZN87397.1 - 1.6e-27 96.8 0.4 1.6e-27 96.8 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN87397.1 - 6.5e-12 45.4 0.0 3.2e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN87397.1 - 6.6e-12 45.3 0.0 6.3e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KZN87397.1 - 0.00018 20.1 0.0 0.00028 19.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 KZN87397.1 - 0.0036 16.7 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 KZN87397.1 - 0.056 14.3 0.2 18 6.3 0.0 3.1 2 1 0 2 2 2 0 EthD domain Abhydrolase_4 PF08386.5 KZN87397.1 - 0.07 13.0 0.0 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein Metallophos PF00149.23 KZN87398.1 - 8.3e-37 126.5 0.1 6.8e-32 110.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FAD_binding_3 PF01494.14 KZN87399.1 - 3.5e-80 269.7 0.0 4.3e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KZN87399.1 - 4.2e-47 159.9 0.0 6.8e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 KZN87399.1 - 9.8e-05 22.3 0.9 0.0008 19.3 0.6 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN87399.1 - 0.00012 21.2 0.1 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KZN87399.1 - 0.0002 20.3 0.2 0.00046 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KZN87399.1 - 0.00024 20.1 0.1 0.00044 19.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN87399.1 - 0.00045 20.1 0.1 0.0014 18.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KZN87399.1 - 0.0015 17.6 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 KZN87399.1 - 0.027 13.2 0.0 0.23 10.2 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.22 KZN87399.1 - 0.061 13.7 0.1 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN87399.1 - 0.068 11.7 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KZN87399.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_7 PF00840.15 KZN87400.1 - 4.1e-223 740.4 18.5 4.1e-223 740.4 12.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KZN87400.1 - 3.9e-13 48.7 13.0 3.9e-13 48.7 9.0 4.0 5 0 0 5 5 5 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.6 KZN87400.1 - 0.58 7.9 7.8 0.93 7.2 5.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Formyl_trans_N PF00551.14 KZN87401.1 - 5.9e-39 133.4 0.2 7.6e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 KZN87401.1 - 1.8e-08 33.6 0.1 1.2e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 KZN87401.1 - 5.1e-08 32.5 0.1 4.2e-07 29.5 0.0 2.4 2 2 0 2 2 2 1 ACT domain NUDIX PF00293.23 KZN87402.1 - 1.9e-10 40.4 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Cellulase PF00150.13 KZN87403.1 - 2.6e-58 197.4 0.6 3.5e-58 197.0 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KZN87403.1 - 3.3e-12 45.8 10.1 3.3e-12 45.8 7.0 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Aconitase PF00330.15 KZN87404.1 - 1.3e-36 126.1 0.3 2.5e-20 72.3 0.0 3.2 1 1 2 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN87404.1 - 0.00071 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain UBN2_3 PF14244.1 KZN87405.1 - 0.0019 17.7 0.7 0.19 11.3 0.1 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Transp_cyt_pur PF02133.10 KZN87406.1 - 9.3e-130 433.0 48.2 2.8e-127 424.9 33.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CutC PF03932.9 KZN87407.1 - 2.8e-43 147.5 0.0 4.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 CutC family DHquinase_I PF01487.10 KZN87407.1 - 0.026 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Type I 3-dehydroquinase DUF1485 PF07364.7 KZN87408.1 - 1.9e-75 253.7 0.0 2.7e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 KZN87408.1 - 1.1e-37 129.2 0.0 2.4e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 MlrC C-terminus Ribonuc_L-PSP PF01042.16 KZN87409.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP polyprenyl_synt PF00348.12 KZN87410.1 - 1.1e-49 168.6 0.0 1.3e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase BpuJI_N PF11564.3 KZN87410.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal FAD_binding_3 PF01494.14 KZN87411.1 - 2.1e-26 92.8 0.1 7e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KZN87411.1 - 8.6e-05 21.7 0.4 0.29 10.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KZN87411.1 - 0.00011 21.2 0.4 0.027 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN87411.1 - 0.00042 20.2 0.2 0.0013 18.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KZN87411.1 - 0.005 15.6 0.0 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase FAD_binding_2 PF00890.19 KZN87411.1 - 0.012 14.4 0.5 0.024 13.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KZN87411.1 - 0.02 13.8 0.3 0.13 11.1 0.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN87411.1 - 0.045 13.6 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN87411.1 - 0.13 10.8 1.7 8.6 4.8 0.2 2.5 2 1 0 3 3 3 0 Tryptophan halogenase polyprenyl_synt PF00348.12 KZN87412.1 - 8.6e-12 44.4 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Glyco_hydro_43 PF04616.9 KZN87413.1 - 3.8e-58 196.8 2.5 1.5e-57 194.8 1.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3425 PF11905.3 KZN87413.1 - 1.8e-37 128.2 5.4 4.8e-37 126.8 3.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KZN87413.1 - 0.86 9.5 8.5 1.4 8.9 5.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.11 KZN87414.1 - 5.3e-20 71.4 51.0 2.9e-14 52.5 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3353 PF11833.3 KZN87414.1 - 0.69 9.3 3.8 2 7.8 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) ACOX PF01756.14 KZN87415.1 - 8.1e-39 132.9 0.0 2.3e-38 131.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KZN87415.1 - 2e-28 99.2 1.4 4e-28 98.2 1.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KZN87415.1 - 5.5e-12 45.0 1.9 7.7e-12 44.5 0.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KZN87415.1 - 8.7e-06 25.9 0.3 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Sugar_tr PF00083.19 KZN87416.1 - 1.4e-95 320.5 27.7 1.6e-95 320.3 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87416.1 - 4.3e-24 84.8 36.6 7.8e-18 64.3 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN87416.1 - 6.6e-05 21.3 0.5 6.6e-05 21.3 0.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN87417.1 - 2.4e-109 365.9 28.0 2.8e-109 365.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87417.1 - 1.4e-19 70.0 31.7 1.6e-14 53.4 4.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN87418.1 - 6.2e-45 153.4 41.1 1.6e-44 152.0 26.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Mak10 PF04112.8 KZN87418.1 - 0.058 12.6 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Zn_clus PF00172.13 KZN87419.1 - 1.4e-07 31.3 11.7 2.6e-07 30.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.1 KZN87421.1 - 2.2e-05 24.8 0.0 6.2e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KZN87421.1 - 0.00085 19.5 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sulfatase PF00884.18 KZN87423.1 - 1.4e-20 73.7 0.8 3.8e-20 72.2 0.6 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN87423.1 - 8.5e-05 22.0 0.1 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RFX_DNA_binding PF02257.10 KZN87424.1 - 1.2e-29 102.3 0.2 3.7e-29 100.6 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain HTH_32 PF13565.1 KZN87424.1 - 0.044 14.5 1.4 0.26 12.1 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain PLDc_2 PF13091.1 KZN87425.1 - 2.1e-11 43.6 0.0 0.0013 18.4 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 KZN87425.1 - 9e-10 38.0 6.0 3.3e-06 26.6 0.5 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Pribosyltran_N PF13793.1 KZN87426.1 - 1.7e-35 121.2 0.1 2.1e-34 117.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KZN87426.1 - 2.9e-33 115.1 0.1 3.1e-28 98.7 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KZN87426.1 - 0.00024 20.8 0.6 0.0088 15.7 0.1 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain Chitin_synth_1 PF01644.12 KZN87426.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Chitin synthase NAD_binding_7 PF13241.1 KZN87427.1 - 1.8e-34 118.0 0.1 2.9e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KZN87427.1 - 5.9e-32 108.8 0.0 9.9e-32 108.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KZN87427.1 - 9.6e-15 53.2 0.1 1.7e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central TrkA_N PF02254.13 KZN87427.1 - 0.015 15.2 0.5 0.035 14.1 0.3 1.6 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KZN87427.1 - 0.066 13.3 0.2 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KZN87427.1 - 0.11 12.2 2.0 0.13 12.0 0.1 1.9 1 1 1 2 2 2 0 ThiF family Sec7 PF01369.15 KZN87428.1 - 2e-64 216.7 0.4 6.9e-64 215.0 0.3 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KZN87428.1 - 6.8e-52 175.2 3.0 6.8e-52 175.2 2.1 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KZN87428.1 - 3.2e-32 109.8 0.9 7.7e-31 105.4 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 KZN87429.1 - 1.8e-75 253.2 0.2 2.3e-75 252.8 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KZN87429.1 - 3.8e-17 61.6 0.7 1.2e-16 60.0 0.3 2.1 1 1 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KZN87429.1 - 9e-13 47.6 0.6 2.3e-12 46.3 0.4 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KZN87429.1 - 0.23 11.7 0.1 0.23 11.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) SseC PF04888.7 KZN87430.1 - 0.0058 16.0 0.3 0.0073 15.6 0.2 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ETRAMP PF09716.5 KZN87430.1 - 3.6 7.5 6.4 22 5.1 4.4 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) V-SNARE_C PF12352.3 KZN87431.1 - 4.4e-14 52.2 0.3 6.6e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KZN87431.1 - 0.00048 19.7 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 Sec20 DUF1785 PF08699.5 KZN87431.1 - 0.071 12.4 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) Sigma70_r4 PF04545.11 KZN87431.1 - 0.09 12.1 0.2 0.19 11.0 0.2 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 Ldh_1_C PF02866.13 KZN87432.1 - 1.1e-42 145.7 0.0 1.6e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KZN87432.1 - 8.3e-42 142.3 0.0 1.4e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KZN87432.1 - 0.0016 17.1 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KZN87432.1 - 0.045 12.8 0.0 0.8 8.7 0.0 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 KZN87432.1 - 0.045 14.0 0.2 0.42 10.9 0.0 2.6 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.24 KZN87433.1 - 4.8e-16 59.1 0.0 1.8e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KZN87433.1 - 1.2e-05 25.0 0.1 4.5e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KZN87433.1 - 0.00062 19.4 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN87433.1 - 0.0013 18.8 4.3 0.0034 17.5 0.5 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KZN87433.1 - 0.0015 18.1 0.3 0.0098 15.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN87433.1 - 0.011 15.6 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KZN87433.1 - 0.013 15.5 0.0 0.013 15.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain NPR2 PF06218.6 KZN87433.1 - 0.058 12.0 0.0 0.14 10.8 0.0 1.6 1 0 0 1 1 1 0 Nitrogen permease regulator 2 ArgK PF03308.11 KZN87433.1 - 0.086 11.6 0.8 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein HbrB PF08539.6 KZN87435.1 - 6.4e-53 178.8 0.0 9.1e-53 178.3 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Flocculin PF00624.13 KZN87435.1 - 0.23 11.3 2.7 0.62 9.9 1.9 1.7 1 0 0 1 1 1 0 Flocculin repeat Gon7 PF08738.5 KZN87436.1 - 3e-16 59.2 5.5 4.6e-14 52.2 1.6 2.0 1 1 1 2 2 2 2 Gon7 family HrpB7 PF09486.5 KZN87436.1 - 0.0052 16.7 0.6 0.006 16.5 0.4 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) FlxA PF14282.1 KZN87436.1 - 0.019 14.8 1.3 0.025 14.5 0.9 1.1 1 0 0 1 1 1 0 FlxA-like protein Vps39_1 PF10366.4 KZN87437.1 - 1.5e-31 108.5 0.0 8.8e-29 99.6 0.0 3.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KZN87437.1 - 1.7e-31 108.6 0.0 3.3e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KZN87437.1 - 7e-20 71.5 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 KZN87437.1 - 4.4e-10 39.3 5.5 1.1e-08 34.8 2.5 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.23 KZN87437.1 - 0.0019 17.7 1.7 13 5.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KZN87437.1 - 0.017 14.7 3.7 1.8 8.2 0.7 3.9 2 1 2 4 4 4 0 TPR repeat Apc3 PF12895.2 KZN87437.1 - 0.14 12.2 3.1 3.8 7.6 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KZN87437.1 - 0.31 11.0 2.6 21 5.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat 6PF2K PF01591.13 KZN87438.1 - 1.2e-77 259.9 0.0 1.7e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KZN87438.1 - 3.8e-33 114.8 0.0 7.8e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KZN87438.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KZN87438.1 - 0.00017 20.8 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KZN87438.1 - 0.015 16.1 0.1 0.16 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 KZN87439.1 - 3.4e-16 58.6 0.0 2e-12 46.5 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN87439.1 - 5.9e-15 55.0 0.0 2.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN87439.1 - 7.7e-10 38.4 0.0 8.4e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KZN87439.1 - 0.013 15.1 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 Laminin_G_2 PF02210.19 KZN87439.1 - 0.078 13.0 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Laminin G domain Sugar_tr PF00083.19 KZN87440.1 - 8.1e-82 275.1 29.1 1e-81 274.8 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87440.1 - 8.4e-18 64.2 24.2 8.4e-18 64.2 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KZN87441.1 - 2.9e-23 82.1 0.0 4.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.9 KZN87443.1 - 2.5e-41 142.0 0.3 4.7e-41 141.1 0.1 1.5 1 1 1 2 2 2 1 Amidohydrolase RINGv PF12906.2 KZN87445.1 - 9e-08 32.0 3.4 9e-08 32.0 2.3 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RanBP PF00641.13 KZN87445.1 - 0.052 12.6 0.1 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-BED PF02892.10 KZN87445.1 - 0.056 13.1 0.3 0.056 13.1 0.2 1.8 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.1 KZN87445.1 - 0.39 10.5 11.0 3.2 7.6 7.6 2.1 1 1 0 1 1 1 0 Ring finger domain DUF2752 PF10825.3 KZN87445.1 - 1.1 9.3 5.0 0.83 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) DUF1206 PF06724.6 KZN87445.1 - 2.2 8.0 8.3 1.1 9.0 2.7 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) PHD PF00628.24 KZN87445.1 - 7.9 6.2 8.5 2.6 7.8 3.7 1.7 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 KZN87446.1 - 2.1e-56 190.2 0.0 1.3e-31 109.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KZN87446.1 - 1.7e-11 43.2 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 KZN87446.1 - 0.048 12.1 0.1 0.67 8.3 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Methyltransf_2 PF00891.13 KZN87446.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Rad51 PF08423.6 KZN87448.1 - 2.2e-10 39.8 0.0 2e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KZN87448.1 - 2.2e-07 30.5 0.0 1.3e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 KZN87448.1 - 4.4e-07 29.2 0.0 7.6e-07 28.4 0.0 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KZN87448.1 - 9.1e-06 24.9 0.0 2.1e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 KZN87448.1 - 0.00035 20.2 0.8 0.0034 17.0 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain IstB_IS21 PF01695.12 KZN87448.1 - 0.0011 18.3 0.1 0.0035 16.7 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.1 KZN87448.1 - 0.0016 18.0 0.0 0.0053 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KZN87448.1 - 0.0028 17.1 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KZN87448.1 - 0.003 18.3 0.0 0.015 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KZN87448.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 KZN87448.1 - 0.025 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 KZN87448.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.20 KZN87448.1 - 0.047 13.1 0.0 0.063 12.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 KZN87448.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KZN87448.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KZN87448.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MOSC PF03473.12 KZN87449.1 - 4.7e-18 64.9 0.0 9.2e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KZN87449.1 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Xan_ur_permease PF00860.15 KZN87451.1 - 4.1e-63 213.2 30.7 1.1e-62 211.7 21.3 1.6 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.19 KZN87452.1 - 6e-19 68.4 13.6 1e-18 67.7 9.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KZN87452.1 - 9.6e-17 60.5 0.1 2.5e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2225 PF09986.4 KZN87452.1 - 0.033 13.6 0.0 0.079 12.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Peptidase_M3 PF01432.15 KZN87453.1 - 5.5e-162 539.9 0.0 7.5e-162 539.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.3 KZN87453.1 - 0.0028 17.0 0.0 0.0079 15.6 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal EF-hand_7 PF13499.1 KZN87455.1 - 1.6e-12 47.3 0.3 1.6e-09 37.7 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN87455.1 - 2e-09 36.5 0.9 0.0084 15.9 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 KZN87455.1 - 2.3e-08 33.8 0.0 0.0014 18.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KZN87455.1 - 1.3e-07 30.4 0.8 0.013 14.7 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KZN87455.1 - 2.9e-06 26.8 0.6 0.00084 18.9 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain pair UPF0154 PF03672.8 KZN87455.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KZN87455.1 - 0.11 11.8 1.5 2.1 7.8 0.7 2.8 2 0 0 2 2 2 0 EF hand Fungal_trans PF04082.13 KZN87456.1 - 8e-64 215.0 0.4 1.1e-63 214.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KZN87456.1 - 0.0015 18.7 11.9 0.0031 17.7 0.5 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN87456.1 - 0.0016 18.7 0.9 0.0016 18.7 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN87456.1 - 0.034 14.4 1.6 0.034 14.4 1.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Xpo1 PF08389.7 KZN87457.1 - 3.6e-26 91.8 0.2 1.5e-24 86.6 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KZN87457.1 - 0.00012 21.8 0.1 0.00084 19.2 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 KZN87457.1 - 0.084 13.3 0.3 4.4 7.9 0.0 4.3 4 1 0 4 4 4 0 HEAT-like repeat LSM PF01423.17 KZN87458.1 - 3e-15 55.5 0.0 3.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain 5-FTHF_cyc-lig PF01812.15 KZN87459.1 - 1.1e-33 116.5 0.0 1.3e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 KZN87460.1 - 2.9e-86 288.2 0.0 3.3e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal JmjN PF02375.12 KZN87460.1 - 0.075 12.5 0.5 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 jmjN domain YqeY PF09424.5 KZN87461.1 - 5.7e-20 71.6 2.6 6.5e-20 71.4 1.8 1.0 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_C PF03177.9 KZN87462.1 - 2.4e-130 435.8 5.0 2.7e-129 432.3 3.5 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KZN87462.1 - 1.3e-86 291.0 0.5 2e-86 290.3 0.4 1.3 1 0 0 1 1 1 1 Nup133 N terminal like TauD PF02668.11 KZN87463.1 - 3.9e-45 154.5 0.1 4.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2781 PF10914.3 KZN87464.1 - 1.8e-43 147.8 11.0 2.1e-43 147.6 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Vma12 PF11712.3 KZN87464.1 - 1.9 8.2 4.2 0.35 10.5 0.3 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TMCO5 PF14992.1 KZN87464.1 - 2.2 7.3 4.4 0.33 10.0 0.5 1.4 2 0 0 2 2 2 0 TMCO5 family Asp_protease PF09668.5 KZN87465.1 - 1.2e-60 202.5 0.1 1.8e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KZN87465.1 - 1.9e-10 41.1 0.0 4.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KZN87465.1 - 9.2e-08 31.3 0.0 1.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KZN87465.1 - 3e-07 30.0 0.0 6.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KZN87465.1 - 3.2e-06 27.1 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KZN87465.1 - 1.6e-05 24.6 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KZN87465.1 - 0.0014 18.5 0.1 0.0057 16.5 0.0 2.1 2 1 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KZN87465.1 - 0.0022 17.6 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KZN87465.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain CDC45 PF02724.9 KZN87466.1 - 3.7 5.4 9.1 6.7 4.6 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.16 KZN87467.1 - 3.8e-14 52.6 0.1 5.9e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.4 KZN87468.1 - 2.2e-86 289.4 15.4 2.2e-86 289.4 10.7 2.0 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KZN87468.1 - 5.2e-33 112.7 1.2 5.2e-33 112.7 0.8 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) PIRT PF15099.1 KZN87468.1 - 0.22 10.7 3.1 2.9 7.1 0.4 2.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family ABC_membrane PF00664.18 KZN87469.1 - 5.5e-84 281.8 37.0 3.2e-43 148.1 9.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN87469.1 - 5.3e-68 227.5 0.0 4.8e-33 114.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN87469.1 - 2.8e-14 52.8 0.1 2.2e-05 23.7 0.7 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN87469.1 - 5e-10 39.8 0.1 0.52 10.2 0.1 4.3 2 2 1 3 3 3 3 AAA domain ABC_ATPase PF09818.4 KZN87469.1 - 5.2e-10 38.4 0.3 0.0024 16.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KZN87469.1 - 1.1e-08 35.2 0.6 0.0013 18.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KZN87469.1 - 3e-08 33.0 0.9 0.00082 18.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KZN87469.1 - 5e-08 33.7 0.0 0.01 16.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KZN87469.1 - 2.3e-07 31.0 0.3 3.8 7.7 0.0 4.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KZN87469.1 - 7.5e-06 25.2 0.1 0.13 11.4 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN87469.1 - 1e-05 25.0 1.0 0.15 11.4 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 KZN87469.1 - 4.1e-05 23.1 0.8 0.99 8.7 0.1 4.0 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 KZN87469.1 - 4.2e-05 23.7 3.8 0.22 11.6 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KZN87469.1 - 0.00017 21.2 3.7 2.3 7.7 0.0 4.4 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 KZN87469.1 - 0.00029 20.7 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN87469.1 - 0.00029 21.1 0.0 0.54 10.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 KZN87469.1 - 0.0012 18.6 0.7 3.1 7.5 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KZN87469.1 - 0.0022 17.8 5.7 0.66 9.9 0.2 3.8 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KZN87469.1 - 0.003 17.2 0.2 2.3 8.0 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 KZN87469.1 - 0.0048 16.6 0.2 5.7 6.6 0.0 3.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 KZN87469.1 - 0.0057 15.3 0.1 0.072 11.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KZN87469.1 - 0.0065 16.8 0.0 4 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KZN87469.1 - 0.007 16.2 0.0 1.2 9.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.17 KZN87469.1 - 0.0071 15.8 0.1 1.1 8.6 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KZN87469.1 - 0.012 15.7 0.0 3.3 7.9 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.1 KZN87469.1 - 0.023 14.6 0.6 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KZN87469.1 - 0.027 13.5 0.1 2.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.13 KZN87469.1 - 0.048 13.2 0.0 2.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KZN87469.1 - 0.53 10.2 2.4 10 6.1 0.1 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase APH PF01636.18 KZN87470.1 - 1.1e-08 35.0 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN87470.1 - 2e-05 24.3 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase HERV-K_env_2 PF13804.1 KZN87470.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Pkinase PF00069.20 KZN87470.1 - 0.062 12.4 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 KZN87470.1 - 0.07 12.4 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Ribosomal_L39 PF00832.15 KZN87471.1 - 6.2e-22 76.7 12.0 7.2e-22 76.5 8.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 KZN87472.1 - 1.1e-39 134.3 2.0 1.7e-39 133.6 1.4 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KZN87472.1 - 1.8e-23 82.3 0.1 4.3e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KZN87472.1 - 0.094 12.7 0.4 0.16 11.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 KZN87473.1 - 3e-47 161.5 20.4 3.7e-47 161.2 14.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 KZN87474.1 - 8.4e-22 76.3 10.6 1.7e-21 75.4 7.3 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 KZN87474.1 - 4e-19 67.7 2.0 5.9e-19 67.2 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 KZN87474.1 - 4.8e-16 58.0 0.8 2.1e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 KZN87474.1 - 1.1e-08 34.5 2.5 2.3e-08 33.5 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KZN87474.1 - 0.0004 20.2 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KZN87474.1 - 0.0019 18.3 0.0 0.0037 17.4 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.5 KZN87474.1 - 0.047 13.2 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Arteri_Gl PF00951.13 KZN87475.1 - 0.39 10.2 3.0 0.59 9.7 2.1 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein ABC2_membrane_4 PF12730.2 KZN87475.1 - 0.62 9.1 0.0 0.62 9.1 0.0 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 KZN87475.1 - 3.6 6.5 6.1 6.1 5.7 4.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Sds3 PF08598.6 KZN87476.1 - 0.0019 17.7 5.3 0.0019 17.7 3.6 2.1 2 1 0 2 2 2 1 Sds3-like eIF-6 PF01912.13 KZN87477.1 - 4.9e-82 273.8 1.0 6.4e-82 273.4 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family SET PF00856.23 KZN87478.1 - 3.9e-21 76.0 1.8 1.1e-20 74.5 0.2 2.6 2 1 0 2 2 2 1 SET domain SRI PF08236.6 KZN87478.1 - 2.7e-18 65.6 5.7 2.7e-18 65.6 4.0 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 KZN87478.1 - 9e-05 22.2 2.1 0.00021 21.0 1.5 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 KZN87478.1 - 0.026 14.0 0.1 0.085 12.3 0.0 1.9 1 0 0 1 1 1 0 TFIIS helical bundle-like domain AT_hook PF02178.14 KZN87479.1 - 0.0035 16.8 1.4 0.018 14.6 1.0 2.4 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.20 KZN87480.1 - 5.4e-58 196.1 0.0 8.3e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87480.1 - 7.5e-34 116.9 0.0 6.8e-32 110.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KZN87480.1 - 1.2e-09 37.5 0.0 3.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN87480.1 - 0.0072 16.0 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 KZN87481.1 - 3.4e-24 85.1 0.0 4.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KZN87481.1 - 0.013 15.3 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.20 KZN87482.1 - 8.8e-62 208.5 0.0 1.3e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87482.1 - 1.1e-25 90.1 0.0 1.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN87482.1 - 0.0071 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN87482.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN87482.1 - 0.03 14.0 2.7 1.8 8.2 0.0 3.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family Corona_nucleoca PF00937.13 KZN87482.1 - 0.24 10.3 6.7 0.41 9.5 4.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein BAR PF03114.13 KZN87483.1 - 2.6e-62 210.3 4.8 3.2e-62 210.0 3.3 1.1 1 0 0 1 1 1 1 BAR domain APG6 PF04111.7 KZN87483.1 - 0.16 11.0 2.0 2.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3340 PF11818.3 KZN87483.1 - 0.44 10.5 5.5 0.1 12.5 0.4 2.1 2 1 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pept_tRNA_hydro PF01195.14 KZN87484.1 - 3.4e-18 65.7 0.0 6.5e-05 22.5 0.0 3.1 2 1 1 3 3 3 3 Peptidyl-tRNA hydrolase Brix PF04427.13 KZN87486.1 - 9.3e-39 133.0 0.1 1.3e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 KZN87486.1 - 1.8 6.3 27.7 2.5 5.9 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 KZN87486.1 - 2.2 5.8 6.6 2.7 5.5 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein tRNA-synt_2b PF00587.20 KZN87487.1 - 5.7e-66 221.3 0.1 8.8e-66 220.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KZN87487.1 - 1e-21 76.6 0.0 1e-21 76.6 0.0 2.6 3 1 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 KZN87489.1 - 8.6e-70 234.8 0.0 1.5e-69 234.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87489.1 - 2.3e-51 174.3 0.1 4.1e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KZN87489.1 - 1.5e-23 82.9 0.4 2.2e-22 79.1 0.0 2.8 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 KZN87489.1 - 1.9e-17 63.5 0.1 4.2e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 KZN87489.1 - 3e-07 29.6 0.0 9.3e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH PF00169.24 KZN87489.1 - 1.2e-05 25.4 0.1 2.6e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 KZN87489.1 - 0.0074 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN87489.1 - 0.035 12.9 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 KZN87490.1 - 1.7e-48 164.8 0.0 2.5e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 KZN87491.1 - 6e-26 90.4 0.0 8.8e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_2 PF07719.12 KZN87492.1 - 2e-25 86.5 29.0 0.0002 21.0 0.2 11.8 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 KZN87492.1 - 3.3e-25 87.5 31.7 6.7e-06 25.6 0.0 11.0 10 2 3 13 13 13 7 TPR repeat TPR_1 PF00515.23 KZN87492.1 - 1.6e-21 74.9 17.3 0.0012 18.3 0.0 10.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 KZN87492.1 - 3.5e-19 68.8 23.4 2.8e-06 27.5 0.1 8.9 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 KZN87492.1 - 4.6e-15 54.7 31.6 0.014 15.9 0.0 11.6 12 2 2 14 14 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 KZN87492.1 - 1.5e-14 53.7 22.8 0.00036 20.4 0.2 9.3 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 KZN87492.1 - 2e-14 52.1 16.8 0.016 14.9 0.0 9.9 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN87492.1 - 3.4e-12 46.6 38.0 0.00012 22.6 0.0 11.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 KZN87492.1 - 3.2e-08 32.7 21.4 0.0078 15.9 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN87492.1 - 4.3e-07 29.9 29.7 0.011 16.0 0.0 12.0 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN87492.1 - 9.5e-07 28.5 12.7 0.61 10.4 0.0 10.7 13 1 1 14 14 14 1 Tetratricopeptide repeat PBD PF00786.23 KZN87494.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.7 3 0 0 3 3 3 0 P21-Rho-binding domain Pax7 PF12360.3 KZN87495.1 - 0.00051 20.2 0.3 1.5 9.1 0.0 2.4 2 0 0 2 2 2 2 Paired box protein 7 Es2 PF09751.4 KZN87496.1 - 2.6e-115 386.1 3.2 3e-115 385.9 2.2 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 APOC4 PF15119.1 KZN87496.1 - 0.088 12.7 0.1 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein C4 Mid1 PF12929.2 KZN87497.1 - 3.6e-155 516.8 7.7 3.6e-155 516.8 5.3 1.3 2 0 0 2 2 2 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KZN87497.1 - 0.051 13.9 3.7 0.6 10.4 0.4 2.7 2 0 0 2 2 2 0 Fz domain CorA PF01544.13 KZN87498.1 - 5e-46 157.0 0.0 7.3e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.21 KZN87499.1 - 7.4e-14 51.5 0.0 1.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KZN87499.1 - 2.2e-05 24.5 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SPC12 PF06645.8 KZN87500.1 - 2.2e-28 97.8 0.1 2.7e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.7 KZN87500.1 - 0.013 14.5 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 zf-rbx1 PF12678.2 KZN87501.1 - 7.8e-36 122.0 13.5 9.8e-36 121.7 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN87501.1 - 1.6e-17 63.1 10.3 2e-17 62.7 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KZN87501.1 - 3.3e-07 30.0 12.7 2.1e-06 27.4 8.8 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KZN87501.1 - 0.0012 18.4 11.9 0.022 14.4 8.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN87501.1 - 0.0033 17.0 9.7 0.3 10.7 6.9 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN87501.1 - 0.045 13.7 13.1 0.048 13.6 5.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KZN87501.1 - 0.18 11.7 9.3 0.75 9.8 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KZN87501.1 - 0.42 10.3 6.5 1.1 9.0 2.2 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 KZN87501.1 - 0.67 10.1 10.3 43 4.3 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KZN87501.1 - 0.7 9.9 9.7 1.6 8.7 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 KZN87501.1 - 1.1 9.0 11.9 7.9 6.3 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.1 KZN87502.1 - 6.3e-06 26.1 4.7 6.3e-06 26.1 3.3 4.8 4 2 0 4 4 4 1 Proline-rich nuclear receptor coactivator SMI1_KNR4 PF09346.5 KZN87504.1 - 1.3e-35 122.2 0.0 2.3e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.15 KZN87505.1 - 6.1e-05 22.6 0.0 9.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin UAA PF08449.6 KZN87506.1 - 4.5e-12 45.5 18.6 5.6e-12 45.1 12.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KZN87506.1 - 3.1e-10 39.9 5.9 3.1e-10 39.9 4.1 3.0 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KZN87506.1 - 0.00075 19.5 5.3 0.00075 19.5 3.7 2.3 2 0 0 2 2 2 1 EamA-like transporter family zf-C2H2_jaz PF12171.3 KZN87507.1 - 4.9e-10 39.2 5.5 0.02 15.0 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN87507.1 - 7.7e-08 32.2 6.8 0.025 14.7 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN87507.1 - 1.7e-07 30.9 8.4 0.016 15.0 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN87507.1 - 5.2e-06 26.4 12.2 0.038 14.3 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87507.1 - 0.001 19.2 12.1 0.25 11.7 0.5 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KZN87507.1 - 0.082 13.0 9.5 0.15 12.1 4.4 3.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 KZN87507.1 - 1.1 9.1 6.2 0.14 12.1 1.3 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.1 KZN87507.1 - 1.3 9.4 12.8 8 6.9 1.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain C1_4 PF07975.7 KZN87507.1 - 1.8 8.6 7.7 11 6.0 4.2 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain CpXC PF14353.1 KZN87507.1 - 6.9 6.6 6.0 5.7 6.9 0.2 2.7 1 1 2 3 3 3 0 CpXC protein DUF2431 PF10354.4 KZN87508.1 - 2.4e-43 147.9 0.0 7e-41 139.9 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Ribosomal_L19e PF01280.15 KZN87508.1 - 0.053 13.2 0.3 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L19e Sigma70_ner PF04546.8 KZN87508.1 - 0.56 9.7 7.2 3.8 7.0 1.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CLTH PF10607.4 KZN87509.1 - 3.6e-35 120.7 1.2 6.9e-35 119.8 0.8 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KZN87509.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 LisH UL73_N PF12522.3 KZN87509.1 - 0.36 10.4 8.5 0.83 9.2 5.9 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal DKCLD PF08068.7 KZN87510.1 - 1.1e-28 98.9 0.0 6.5e-28 96.4 0.0 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KZN87510.1 - 6.8e-23 81.4 1.5 3.5e-20 72.6 0.1 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KZN87510.1 - 3.6e-21 74.6 1.2 6.9e-21 73.7 0.8 1.5 1 0 0 1 1 1 1 PUA domain DUF3987 PF13148.1 KZN87510.1 - 1.8 7.0 8.8 2.4 6.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4407 PF14362.1 KZN87510.1 - 2.4 7.0 5.4 3.8 6.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_polI_A34 PF08208.6 KZN87510.1 - 5.4 6.6 24.7 8.5 5.9 17.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TFIIF_alpha PF05793.7 KZN87510.1 - 6 5.1 25.4 8.2 4.6 17.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 KZN87510.1 - 6.5 6.6 11.3 9 6.1 7.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 KZN87510.1 - 8.8 6.1 13.2 12 5.6 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DER1 PF04511.10 KZN87511.1 - 3.2e-27 95.3 4.8 3.6e-27 95.1 3.4 1.0 1 0 0 1 1 1 1 Der1-like family PDT PF00800.13 KZN87513.1 - 1.7e-66 223.2 0.0 2.3e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KZN87513.1 - 0.00023 20.5 0.0 0.00058 19.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.10 KZN87514.1 - 5.1e-45 153.0 0.0 9.1e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KZN87514.1 - 1.6e-37 128.1 0.6 3.6e-37 127.0 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KZN87514.1 - 1.5e-28 99.0 0.0 2.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KZN87514.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.13 KZN87515.1 - 5.6e-68 229.3 26.9 6.5e-68 229.0 18.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3321 PF11968.3 KZN87516.1 - 2.3e-93 311.8 0.0 2.8e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KZN87516.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L23eN PF03939.8 KZN87517.1 - 2.5e-21 75.4 7.4 2.5e-21 75.4 5.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KZN87517.1 - 2.8e-17 62.4 2.6 5.3e-17 61.5 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 KZN87517.1 - 0.12 12.2 0.7 0.23 11.3 0.5 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain zf-Tim10_DDP PF02953.10 KZN87518.1 - 1.8e-21 75.2 2.9 2.3e-21 74.8 2.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Latrotoxin_C PF15658.1 KZN87518.1 - 0.025 14.4 0.1 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Latrotoxin C-terminal domain FANCI_HD2 PF14680.1 KZN87518.1 - 0.063 12.3 1.0 0.071 12.2 0.7 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 G10 PF01125.12 KZN87519.1 - 3e-66 221.4 4.2 3.4e-66 221.2 2.9 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 KZN87520.1 - 6.9e-37 125.3 0.2 1.1e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Fork head domain AA_kinase PF00696.23 KZN87521.1 - 5e-39 134.2 0.0 7.7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 KZN87521.1 - 1.3e-11 43.8 1.4 2.6e-09 36.4 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KZN87521.1 - 3.1e-11 42.5 1.1 1.6e-08 33.8 0.1 3.5 3 0 0 3 3 3 2 ACT domain Peptidase_C78 PF07910.8 KZN87523.1 - 6.7e-71 237.8 0.0 8.8e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 KZN87523.1 - 0.016 15.3 3.2 3.5 7.8 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Siva PF05458.7 KZN87523.1 - 0.064 12.8 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) AAA_18 PF13238.1 KZN87524.1 - 9e-27 93.9 0.4 1.5e-26 93.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KZN87524.1 - 4.8e-14 53.2 0.4 9.3e-14 52.2 0.2 1.5 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KZN87524.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN87524.1 - 0.001 18.9 0.0 0.023 14.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KZN87524.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN87524.1 - 0.002 18.1 0.0 0.0056 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KZN87524.1 - 0.0026 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ADK PF00406.17 KZN87524.1 - 0.0028 17.5 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 KZN87524.1 - 0.0053 16.0 0.0 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 KZN87524.1 - 0.0072 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KZN87524.1 - 0.0082 15.8 0.3 0.016 14.9 0.1 1.6 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.1 KZN87524.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KZN87524.1 - 0.015 14.7 0.0 0.16 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA-like domain Cytidylate_kin2 PF13189.1 KZN87524.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family DUF2075 PF09848.4 KZN87524.1 - 0.02 13.9 0.2 0.027 13.4 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 KZN87524.1 - 0.028 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KZN87524.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KZN87524.1 - 0.071 12.5 0.2 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 KZN87524.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KZN87524.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KZN87524.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ham1p_like PF01725.11 KZN87525.1 - 2.7e-56 189.9 0.0 3e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.16 KZN87526.1 - 2.2e-249 829.2 0.8 3.4e-249 828.5 0.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 KZN87526.1 - 3e-34 117.0 2.9 3e-34 117.0 2.0 2.3 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 KZN87526.1 - 1.1e-14 52.5 28.3 0.00048 19.5 0.3 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KZN87526.1 - 0.00033 20.8 0.0 0.0019 18.3 0.0 2.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KZN87526.1 - 0.00061 19.0 0.0 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GAS PF13851.1 KZN87526.1 - 0.0012 18.0 27.7 0.031 13.4 9.0 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Myosin_N PF02736.14 KZN87526.1 - 0.0022 17.6 0.6 0.0053 16.4 0.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain TMP_2 PF06791.8 KZN87526.1 - 0.0067 16.0 1.7 0.014 15.0 1.2 1.5 1 0 0 1 1 1 1 Prophage tail length tape measure protein AAA_19 PF13245.1 KZN87526.1 - 0.012 15.3 0.0 0.051 13.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KZN87526.1 - 0.037 13.9 5.2 0.067 13.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 KZN87526.1 - 0.056 12.6 1.1 0.1 11.7 0.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KZN87526.1 - 2.7 7.8 29.6 12 5.7 4.3 3.0 1 1 1 2 2 2 0 Tropomyosin like FUSC PF04632.7 KZN87526.1 - 9.1 4.5 8.6 17 3.6 6.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family NAP PF00956.13 KZN87527.1 - 6.7e-87 290.6 9.4 6.7e-87 290.6 6.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Sigma70_ner PF04546.8 KZN87527.1 - 0.014 15.0 2.3 0.014 15.0 1.6 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region P5-ATPase PF12409.3 KZN87528.1 - 2.6e-39 133.7 0.0 1.7e-38 131.0 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 KZN87528.1 - 1.6e-32 113.2 0.0 1.8e-31 109.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KZN87528.1 - 2.7e-31 108.3 0.0 5.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN87528.1 - 2.8e-17 63.8 0.0 3.7e-16 60.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN87528.1 - 0.00065 19.1 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KZN87528.1 - 0.0018 18.1 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN87528.1 - 0.012 15.2 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NADH_B2 PF14813.1 KZN87529.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 KZN87530.1 - 1.4e-67 227.6 0.0 1.7e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87530.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase 2-Hacid_dh_C PF02826.14 KZN87531.1 - 1.4e-52 177.4 0.0 2.2e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN87531.1 - 2.6e-37 127.2 0.0 3.6e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN87531.1 - 2.9e-05 23.9 1.2 5.7e-05 23.0 0.1 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KZN87531.1 - 0.0037 17.1 0.1 0.0095 15.7 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KZN87531.1 - 0.004 16.5 0.2 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 KZN87531.1 - 0.018 14.5 0.1 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 ACT domain 3HCDH_N PF02737.13 KZN87531.1 - 0.089 12.4 0.6 1.2 8.7 0.2 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KZN87531.1 - 0.096 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain UBN2_3 PF14244.1 KZN87532.1 - 0.00055 19.5 1.1 0.0014 18.1 0.0 2.2 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type MSP7_C PF12948.2 KZN87532.1 - 0.14 12.3 2.9 1.8 8.8 2.0 2.4 1 1 0 1 1 1 0 MSP7-like protein C-terminal domain PH_10 PF15411.1 KZN87533.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain tRNA-synt_2b PF00587.20 KZN87534.1 - 4e-32 111.1 0.0 6.3e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KZN87534.1 - 1.8e-10 40.8 6.1 1.8e-10 40.8 4.2 2.9 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4375 PF14300.1 KZN87534.1 - 1.4 8.9 4.9 0.38 10.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) Ras PF00071.17 KZN87535.1 - 1.5e-45 154.5 0.1 1.7e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN87535.1 - 1.3e-15 57.9 0.1 1.9e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN87535.1 - 2e-08 33.6 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KZN87535.1 - 1.1e-06 28.5 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN87535.1 - 9.6e-06 25.1 0.5 0.0004 19.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KZN87535.1 - 0.00027 20.2 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KZN87535.1 - 0.0051 16.7 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KZN87535.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KZN87535.1 - 0.027 13.7 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.8 KZN87536.1 - 2e-40 138.6 0.0 4.5e-40 137.4 0.0 1.6 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 KZN87537.1 - 3.8e-78 261.4 0.0 4.8e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KZN87537.1 - 0.0044 16.7 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KZN87537.1 - 0.064 12.9 0.2 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 KZN87538.1 - 3.1e-29 100.4 0.2 3.9e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cript PF10235.4 KZN87538.1 - 0.016 15.5 0.4 0.1 12.9 0.3 2.0 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-Sec23_Sec24 PF04810.10 KZN87538.1 - 0.13 11.8 0.9 0.95 9.0 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.1 KZN87538.1 - 0.21 11.5 0.3 0.21 11.5 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_S3Ae PF01015.13 KZN87539.1 - 1.2e-80 269.4 6.1 1.5e-80 269.1 4.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family HABP4_PAI-RBP1 PF04774.10 KZN87540.1 - 0.001 19.5 3.5 0.002 18.5 2.4 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family YscJ_FliF_C PF08345.6 KZN87540.1 - 0.68 9.8 3.4 0.2 11.6 0.4 1.6 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Nucleoporin_C PF03177.9 KZN87541.1 - 2.7e-112 376.2 0.0 9.6e-112 374.4 0.0 1.7 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KZN87541.1 - 1.2e-66 225.2 0.0 1.6e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Acyl_transf_1 PF00698.16 KZN87542.1 - 9.8e-21 74.3 0.0 9.8e-13 48.1 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 KZN87543.1 - 2.7e-25 88.7 0.0 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3197 PF11432.3 KZN87543.1 - 0.069 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Oxidored_q6 PF01058.17 KZN87544.1 - 1.1e-22 80.0 0.0 1.9e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF3426 PF11906.3 KZN87544.1 - 0.13 11.8 1.2 5.1 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) AA_permease PF00324.16 KZN87545.1 - 9.3e-98 327.6 31.6 1.2e-97 327.3 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN87545.1 - 1.3e-35 122.7 33.7 1.6e-35 122.5 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1761 PF08570.5 KZN87547.1 - 9e-24 83.8 2.5 1e-23 83.7 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) PhaG_MnhG_YufB PF03334.9 KZN87547.1 - 0.58 10.2 0.1 0.58 10.2 0.0 2.6 3 1 0 3 3 3 0 Na+/H+ antiporter subunit QCR10 PF09796.4 KZN87547.1 - 9.1 6.0 6.6 6.6 6.4 0.4 3.0 1 1 2 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Methyltransf_16 PF10294.4 KZN87548.1 - 4e-50 169.6 0.0 5e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KZN87548.1 - 0.00093 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN87548.1 - 0.004 16.7 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN87548.1 - 0.0049 17.4 0.0 0.0076 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN87548.1 - 0.071 12.4 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Mpp10 PF04006.7 KZN87549.1 - 9.8e-86 288.4 60.1 1.3e-77 261.5 17.9 2.2 1 1 1 2 2 2 2 Mpp10 protein DUF2756 PF10956.3 KZN87549.1 - 7.8 6.8 8.8 4.5 7.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) adh_short PF00106.20 KZN87550.1 - 2.7e-29 102.2 0.0 3.8e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87550.1 - 9.8e-29 100.8 0.0 1.2e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87550.1 - 6.4e-12 45.4 0.0 8.7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KZN87550.1 - 0.00048 19.3 0.0 0.026 13.6 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KZN87550.1 - 0.0039 16.9 0.1 0.0081 15.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KZN87550.1 - 0.0042 16.2 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KZN87550.1 - 0.038 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AhpC-TSA PF00578.16 KZN87551.1 - 1.3e-22 79.8 0.0 1.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KZN87551.1 - 5.2e-14 52.0 0.0 7.2e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KZN87551.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PRELI PF04707.9 KZN87552.1 - 3.6e-42 143.5 0.2 4.2e-42 143.3 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.5 KZN87552.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 CTP_transf_2 PF01467.21 KZN87554.1 - 3.8e-17 62.7 0.0 3e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase Glutaredoxin PF00462.19 KZN87555.1 - 8.1e-15 54.5 0.0 1.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.14 KZN87556.1 - 1.8e-29 101.9 0.0 2.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Epimerase_Csub PF13950.1 KZN87556.1 - 0.028 14.3 0.3 0.068 13.1 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit UbiA PF01040.13 KZN87557.1 - 1.7e-32 112.6 19.0 2.2e-32 112.3 13.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2715 PF10895.3 KZN87557.1 - 0.052 13.0 0.1 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2715) JmjC PF02373.17 KZN87558.1 - 3.1e-08 33.8 0.3 9.5e-07 29.0 0.2 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KZN87558.1 - 0.00019 21.5 9.7 0.00019 21.5 6.7 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KZN87558.1 - 0.069 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Coa1 PF08695.5 KZN87560.1 - 7e-43 144.8 0.0 8.7e-43 144.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 KZN87561.1 - 1.3e-37 129.6 4.8 2.6e-36 125.3 3.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 DUF1279 PF06916.8 KZN87562.1 - 5.3e-29 100.3 0.0 7.7e-29 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Zeta_toxin PF06414.7 KZN87562.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Serglycin PF04360.7 KZN87562.1 - 0.17 11.5 1.0 0.33 10.6 0.3 1.7 2 0 0 2 2 2 0 Serglycin Ank_2 PF12796.2 KZN87563.1 - 1.3e-37 128.0 4.3 7e-11 42.3 0.0 5.2 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) SPX PF03105.14 KZN87563.1 - 5e-29 101.9 6.7 1.4e-16 61.1 0.7 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 KZN87563.1 - 9.6e-23 80.1 9.6 2.5e-09 37.3 0.1 7.1 5 3 4 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN87563.1 - 1.1e-17 63.6 6.4 5.5e-05 23.2 0.1 6.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KZN87563.1 - 1.9e-17 62.1 13.3 0.00017 21.2 0.1 8.3 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.1 KZN87563.1 - 1.8e-16 58.5 7.9 0.00013 21.8 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat GDPD PF03009.12 KZN87563.1 - 6.6e-16 58.5 0.1 5e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SKG6 PF08693.5 KZN87564.1 - 3.8e-09 35.7 3.0 3.8e-09 35.7 2.1 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KZN87564.1 - 1.2e-05 24.8 0.3 2.3e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 KZN87564.1 - 2.9e-05 23.8 7.6 0.00026 20.7 5.2 2.0 1 1 0 1 1 1 1 Rifin/stevor family DUF2910 PF11139.3 KZN87564.1 - 0.057 12.5 0.2 0.057 12.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) EphA2_TM PF14575.1 KZN87564.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 KZN87564.1 - 0.16 12.0 1.2 2.1 8.4 0.8 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC_tran PF00005.22 KZN87567.1 - 3e-48 163.5 0.6 6.3e-23 81.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KZN87567.1 - 4.6e-20 71.2 6.5 4.6e-20 71.2 4.5 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 KZN87567.1 - 4.5e-15 56.3 0.1 0.0023 17.9 0.0 4.6 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KZN87567.1 - 1.9e-09 38.4 0.0 0.0018 19.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KZN87567.1 - 4.7e-09 35.7 1.7 0.16 11.1 0.0 4.5 5 0 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KZN87567.1 - 3.3e-06 27.2 0.0 0.017 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN87567.1 - 4.5e-06 26.7 0.4 0.027 14.4 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KZN87567.1 - 4.9e-06 25.9 0.1 0.075 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KZN87567.1 - 5.7e-06 26.2 0.0 0.092 12.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KZN87567.1 - 5.9e-06 26.6 1.7 0.074 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KZN87567.1 - 7.2e-06 25.2 0.0 0.043 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KZN87567.1 - 1.8e-05 25.2 0.0 0.039 14.4 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 KZN87567.1 - 2.3e-05 24.0 0.1 0.1 12.2 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KZN87567.1 - 3.6e-05 23.7 3.6 0.021 14.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 KZN87567.1 - 3.6e-05 23.0 4.7 0.19 10.7 0.0 4.5 4 2 1 5 5 5 2 AAA ATPase domain Dynamin_N PF00350.18 KZN87567.1 - 9.5e-05 22.2 1.8 0.21 11.3 0.0 3.8 4 0 0 4 4 4 1 Dynamin family NACHT PF05729.7 KZN87567.1 - 0.00024 20.8 0.2 0.63 9.6 0.0 3.1 4 0 0 4 4 3 2 NACHT domain AAA_33 PF13671.1 KZN87567.1 - 0.00035 20.4 0.0 0.7 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KZN87567.1 - 0.00087 18.9 0.1 0.051 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KZN87567.1 - 0.00097 19.3 0.1 0.49 10.6 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KZN87567.1 - 0.0013 18.2 0.1 0.19 11.1 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KZN87567.1 - 0.0016 18.7 0.1 0.026 14.8 0.0 4.9 4 1 1 5 5 4 2 AAA domain RNA_helicase PF00910.17 KZN87567.1 - 0.0019 18.3 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KZN87567.1 - 0.0021 17.9 0.0 1.6 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KZN87567.1 - 0.0023 16.7 2.6 0.75 8.5 0.0 2.7 3 0 0 3 3 2 2 ArgK protein Zeta_toxin PF06414.7 KZN87567.1 - 0.0041 16.2 0.0 0.55 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 KZN87567.1 - 0.0049 16.3 1.6 1.8 7.9 0.0 3.7 3 1 0 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 KZN87567.1 - 0.0072 16.0 0.1 1.3 8.7 0.1 2.8 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.9 KZN87567.1 - 0.012 15.2 0.0 4.4 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KZN87567.1 - 0.017 14.7 0.0 3 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KZN87567.1 - 0.017 13.9 0.0 5.3 5.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.1 KZN87567.1 - 0.019 14.8 0.4 9.3 6.2 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 KZN87567.1 - 0.024 14.0 2.0 1.3 8.3 0.2 3.2 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KZN87567.1 - 0.028 13.8 0.4 0.98 8.8 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KZN87567.1 - 0.034 13.6 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KZN87567.1 - 0.063 12.6 0.0 10 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 KZN87567.1 - 0.1 11.8 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.12 KZN87567.1 - 1.8 8.3 0.0 1.8 8.3 0.0 4.0 6 0 0 6 6 5 0 Domain of unknown function DUF87 DUF4200 PF13863.1 KZN87567.1 - 3.9 7.4 19.5 2 8.3 1.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Arch_ATPase PF01637.13 KZN87567.1 - 6 6.4 7.5 20 4.8 0.0 3.6 4 0 0 4 4 4 0 Archaeal ATPase Sugar_tr PF00083.19 KZN87568.1 - 1.7e-105 353.2 21.2 4.2e-105 351.9 14.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN87568.1 - 2.9e-31 108.4 59.6 1.5e-30 106.0 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN87568.1 - 6.2e-06 24.6 4.9 6.2e-06 24.6 3.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KZN87568.1 - 8.4e-05 22.2 2.2 0.00085 19.0 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.14 KZN87568.1 - 0.00041 19.0 8.0 0.0026 16.4 1.1 2.5 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 KZN87568.1 - 0.001 17.2 13.4 0.0014 16.7 1.0 2.7 3 0 0 3 3 3 2 Transmembrane secretion effector PspC PF04024.7 KZN87568.1 - 0.01 15.3 0.3 0.01 15.3 0.2 3.1 3 0 0 3 3 3 1 PspC domain DUF788 PF05620.6 KZN87568.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF788) WD40 PF00400.27 KZN87569.1 - 6.2e-50 165.3 21.7 3.3e-12 45.8 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KZN87569.1 - 2e-05 24.4 13.1 0.014 15.1 0.4 3.9 3 2 1 4 4 4 2 Transcription factor IIIC subunit delta N-term Pec_lyase_C PF00544.14 KZN87572.1 - 3.8e-18 65.6 1.1 6.1e-18 65.0 0.8 1.4 1 0 0 1 1 1 1 Pectate lyase DAN PF03045.10 KZN87573.1 - 0.038 13.4 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 DAN domain Myb_DNA-bind_6 PF13921.1 KZN87576.1 - 5.3e-05 23.2 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN87576.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Zn_clus PF00172.13 KZN87577.1 - 1.9e-06 27.6 9.4 3.7e-06 26.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_8 PF00895.15 KZN87579.1 - 0.05 13.8 0.4 0.076 13.2 0.3 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 Ank_5 PF13857.1 KZN87579.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KZN87580.1 - 0.00075 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KZN87580.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Catalase-rel PF06628.7 KZN87582.1 - 4e-08 32.9 0.0 3.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive F-box-like PF12937.2 KZN87582.1 - 8.6e-05 22.1 0.4 0.0002 20.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN87582.1 - 0.0091 15.6 2.6 0.022 14.4 0.6 2.4 2 0 0 2 2 2 1 F-box domain Pectate_lyase_3 PF12708.2 KZN87584.1 - 7.9e-86 287.8 13.1 1.7e-68 231.1 4.6 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein LysM PF01476.15 KZN87584.1 - 1.4e-10 40.9 0.5 0.001 18.9 0.0 3.6 3 0 0 3 3 3 3 LysM domain End_N_terminal PF12218.3 KZN87584.1 - 3.7e-06 26.3 2.5 0.043 13.2 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KZN87584.1 - 0.0021 17.8 1.3 0.0021 17.8 0.9 2.5 2 0 0 2 2 2 1 Right handed beta helix region Glyco_hydro_18 PF00704.23 KZN87585.1 - 2.8e-70 237.4 0.4 2.8e-70 237.4 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KZN87585.1 - 1.2e-08 34.7 20.6 1.5e-08 34.4 6.1 5.0 4 0 0 4 4 4 2 Chitin recognition protein DNA_pol_E_B PF04042.11 KZN87586.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B MatE PF01554.13 KZN87587.1 - 8.8e-07 28.6 14.9 6.8e-05 22.5 0.3 3.6 4 0 0 4 4 4 3 MatE TPR_16 PF13432.1 KZN87588.1 - 1.6e-05 25.4 12.5 0.00071 20.1 3.5 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN87588.1 - 5.8e-05 22.6 8.9 0.00031 20.3 1.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KZN87588.1 - 0.00057 19.3 2.1 0.074 12.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN87588.1 - 0.041 13.7 7.7 0.31 11.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SpvB PF03534.8 KZN87588.1 - 0.17 10.8 0.1 17 4.2 0.0 2.4 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein TPR_14 PF13428.1 KZN87588.1 - 1.3 9.9 9.3 4.8 8.0 0.4 3.9 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3129 PF11327.3 KZN87591.1 - 1.4e-41 142.3 6.2 1.9e-41 141.8 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Scytalone_dh PF02982.9 KZN87592.1 - 1.2e-17 63.9 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KZN87592.1 - 2.7e-11 43.4 0.3 3.3e-11 43.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain Mitofilin PF09731.4 KZN87594.1 - 2.7 6.5 7.3 0.082 11.5 1.0 1.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CitX PF03802.9 KZN87595.1 - 0.15 11.4 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase PDGF_N PF04692.8 KZN87597.1 - 0.052 14.0 1.3 0.12 12.8 0.2 2.1 2 2 0 2 2 2 0 Platelet-derived growth factor, N terminal region Nucleo_P87 PF07267.6 KZN87597.1 - 1.7 7.2 4.5 2.3 6.7 3.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 KZN87597.1 - 2.5 7.2 5.4 2.6 7.2 2.6 1.7 2 0 0 2 2 2 0 NOA36 protein Mnd1 PF03962.10 KZN87598.1 - 0.32 10.6 5.5 0.47 10.0 3.8 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 KZN87598.1 - 0.89 9.1 8.1 1.1 8.7 5.6 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KZN87598.1 - 1.7 7.5 6.7 1.9 7.4 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3723 PF12520.3 KZN87601.1 - 8e-60 202.7 0.1 4e-54 183.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF2706 PF10913.3 KZN87602.1 - 0.27 10.8 1.7 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Prok-JAB PF14464.1 KZN87605.1 - 0.0024 17.4 0.8 0.0039 16.7 0.4 1.5 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain BAR_2 PF10455.4 KZN87606.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Patatin PF01734.17 KZN87608.1 - 6.2e-21 75.2 1.3 9.6e-21 74.6 0.2 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN87608.1 - 0.0011 18.5 5.2 0.0045 16.6 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN87608.1 - 0.0025 17.8 8.7 0.0086 16.0 6.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN87608.1 - 0.0045 16.6 7.2 0.014 15.1 5.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN87608.1 - 0.12 12.2 9.0 0.39 10.5 6.2 2.0 1 0 0 1 1 1 0 Ring finger domain FxsA PF04186.8 KZN87609.1 - 0.081 12.5 1.7 2.6 7.6 0.0 2.8 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DUF4625 PF15418.1 KZN87610.1 - 0.002 18.2 0.0 0.0056 16.7 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) priB_priC PF07445.7 KZN87612.1 - 0.06 12.8 2.2 0.077 12.4 1.5 1.2 1 0 0 1 1 1 0 Primosomal replication protein priB and priC MAP7 PF05672.6 KZN87612.1 - 0.082 12.2 2.2 0.12 11.7 1.5 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family RUN PF02759.14 KZN87612.1 - 0.084 12.6 0.4 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 RUN domain Syntaxin PF00804.20 KZN87613.1 - 0.04 14.0 0.4 0.052 13.7 0.3 1.2 1 1 0 1 1 1 0 Syntaxin EAP30 PF04157.11 KZN87613.1 - 0.047 12.8 0.5 0.079 12.1 0.3 1.3 1 1 0 1 1 1 0 EAP30/Vps36 family Phage_lysis PF03245.8 KZN87613.1 - 0.071 13.1 0.5 0.077 12.9 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein THOC7 PF05615.8 KZN87613.1 - 0.08 13.2 0.6 0.084 13.1 0.4 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 TMF_DNA_bd PF12329.3 KZN87615.1 - 0.00058 19.6 0.4 0.00058 19.6 0.3 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 KZN87615.1 - 0.015 15.0 2.1 2.2 8.0 0.3 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2390 PF09523.5 KZN87615.1 - 0.022 14.9 1.5 3.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) NPV_P10 PF05531.7 KZN87615.1 - 0.03 14.5 0.6 0.1 12.8 0.4 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 KZN87615.1 - 0.072 13.2 1.8 0.14 12.2 0.3 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KZN87615.1 - 0.077 12.1 2.2 0.17 11.0 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KZN87615.1 - 0.15 11.9 4.4 0.96 9.2 0.1 3.1 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 KZN87615.1 - 0.25 10.8 3.6 1 8.8 0.3 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 KZN87615.1 - 0.35 10.9 4.3 0.25 11.4 0.1 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 KZN87615.1 - 0.37 9.4 6.0 0.41 9.2 0.2 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein priB_priC PF07445.7 KZN87615.1 - 0.59 9.5 6.1 1.6 8.1 0.2 2.8 3 0 0 3 3 3 0 Primosomal replication protein priB and priC UCR_Fe-S_N PF10399.4 KZN87615.1 - 1.5 8.0 3.5 6.9 5.9 0.0 2.6 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4140 PF13600.1 KZN87615.1 - 2 8.8 5.7 1.1 9.7 0.3 2.9 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KZN87615.1 - 2.2 7.8 12.7 0.058 12.9 0.4 3.2 3 1 0 3 3 3 0 IncA protein UBN2 PF14223.1 KZN87616.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN87616.1 - 0.00066 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KZN87616.1 - 0.0038 17.0 4.7 0.0083 16.0 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 KZN87616.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RNase_H PF00075.19 KZN87618.1 - 0.0038 17.5 0.1 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 RNase H TP53IP5 PF15331.1 KZN87620.1 - 0.049 13.5 0.9 0.078 12.8 0.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PDGF_N PF04692.8 KZN87620.1 - 0.059 13.8 0.1 0.23 12.0 0.1 2.0 1 1 0 1 1 1 0 Platelet-derived growth factor, N terminal region Tmemb_9 PF05434.6 KZN87620.1 - 0.64 9.7 2.9 1.4 8.6 0.0 2.1 1 1 1 2 2 2 0 TMEM9 Ank_2 PF12796.2 KZN87621.1 - 3.1e-87 287.0 15.5 3.2e-14 53.0 0.1 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87621.1 - 2.5e-62 203.7 11.9 2.1e-07 30.4 0.0 13.6 13 1 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 KZN87621.1 - 1e-47 159.6 8.8 2e-07 31.3 0.0 10.5 3 3 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87621.1 - 1.5e-46 151.7 5.5 0.00022 21.1 0.0 12.9 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 KZN87621.1 - 1.3e-32 111.0 12.1 1.8e-07 31.1 0.0 8.8 5 4 5 10 10 10 8 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN87621.1 - 1.5e-05 24.6 1.1 2.3e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 F-box-like DUF812 PF05667.6 KZN87622.1 - 0.0095 14.5 1.1 0.012 14.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3734 PF12536.3 KZN87622.1 - 0.056 13.5 0.1 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Patatin phospholipase DUF4206 PF13901.1 KZN87622.1 - 0.13 11.7 0.2 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) BBS1 PF14779.1 KZN87624.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF904 PF06005.7 KZN87624.1 - 0.83 9.9 3.1 1.7 8.9 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) NEMO PF11577.3 KZN87624.1 - 3.8 7.3 6.3 5.6 6.7 2.9 2.2 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO AAA PF00004.24 KZN87627.1 - 3.2e-18 66.1 0.0 6.8e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN87627.1 - 0.00057 19.9 0.6 0.071 13.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KZN87627.1 - 0.0016 19.2 0.1 0.016 15.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KZN87627.1 - 0.011 15.8 2.6 3.3 7.8 0.0 3.5 2 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KZN87627.1 - 0.03 14.0 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3089 PF11288.3 KZN87627.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AAA_19 PF13245.1 KZN87627.1 - 0.099 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain HSDR_N_2 PF13588.1 KZN87628.1 - 0.0095 15.7 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Radial_spoke_3 PF06098.6 KZN87628.1 - 0.041 12.8 13.8 0.037 13.0 8.5 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 Spore_coat_CotO PF14153.1 KZN87628.1 - 0.32 10.4 7.7 0.026 13.9 1.6 1.9 2 0 0 2 2 2 0 Spore coat protein CotO ARGLU PF15346.1 KZN87628.1 - 1.3 8.7 29.5 0.035 13.8 15.4 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 NARP1 PF12569.3 KZN87628.1 - 1.9 7.1 10.2 3.4 6.3 7.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 KZN87628.1 - 2.9 7.2 21.3 0.094 12.1 10.4 1.7 2 0 0 2 2 2 0 DDRGK domain ORC6 PF05460.8 KZN87629.1 - 0.13 11.3 8.2 0.18 10.8 5.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Helitron_like_N PF14214.1 KZN87630.1 - 1.8e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KZN87630.1 - 4.2e-08 32.5 0.8 2.7e-06 26.5 0.6 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 KZN87630.1 - 0.0012 18.6 0.1 0.0044 16.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KZN87630.1 - 0.0071 15.9 0.2 0.019 14.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain Ehrlichia_rpt PF09528.5 KZN87630.1 - 0.18 9.9 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Stb3 PF10330.4 KZN87631.1 - 4.6e-32 109.5 0.0 8.5e-32 108.7 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2823 PF11034.3 KZN87633.1 - 4.8e-33 113.0 16.1 5.4e-33 112.9 11.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF2823 PF11034.3 KZN87634.1 - 8.1e-16 57.9 15.0 4.5e-14 52.3 10.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2823) MRFAP1 PF15155.1 KZN87634.1 - 0.41 10.9 2.8 0.44 10.8 1.9 1.1 1 0 0 1 1 1 0 MORF4 family-associated protein1 Linker_histone PF00538.14 KZN87635.1 - 0.28 11.2 6.5 41 4.3 2.4 3.5 1 1 1 2 2 2 0 linker histone H1 and H5 family CENP-X PF09415.5 KZN87635.1 - 0.78 9.6 2.3 32 4.4 0.0 3.0 2 1 1 3 3 3 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KZN87635.1 - 0.95 8.7 7.8 1.2 8.3 5.4 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like TryThrA_C PF12319.3 KZN87635.1 - 2.9 7.0 11.2 12 4.9 7.7 1.7 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal MARVEL PF01284.18 KZN87636.1 - 5.4e-13 48.9 7.9 7e-13 48.6 5.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.3 KZN87636.1 - 0.00049 19.9 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) DUF2530 PF10745.4 KZN87636.1 - 0.24 11.4 0.7 4.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF373 PF04123.8 KZN87636.1 - 0.95 8.4 4.0 0.62 9.0 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF202 PF02656.10 KZN87636.1 - 1.2 9.3 4.1 53 4.1 2.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HAD_2 PF13419.1 KZN87637.1 - 1.9e-11 44.5 0.0 2.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN87637.1 - 0.019 14.6 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like bZIP_1 PF00170.16 KZN87638.1 - 5.2e-07 29.5 9.8 1.4e-06 28.1 6.8 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN87638.1 - 0.00028 20.6 11.6 0.0022 17.7 8.1 2.4 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KZN87638.1 - 0.0039 17.4 7.3 0.0039 17.4 5.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Bap31 PF05529.7 KZN87638.1 - 7.3 5.9 7.6 17 4.8 5.3 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like RhoGEF PF00621.15 KZN87639.1 - 0.0083 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain RhoGEF PF00621.15 KZN87640.1 - 1.9e-14 53.9 0.0 3e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 KZN87640.1 - 0.06 12.8 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 BAR domain BAR PF03114.13 KZN87641.1 - 0.034 13.6 0.6 0.042 13.3 0.4 1.1 1 0 0 1 1 1 0 BAR domain Esterase_phd PF10503.4 KZN87641.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase zf-BED PF02892.10 KZN87643.1 - 0.0006 19.5 1.0 0.001 18.7 0.7 1.4 1 0 0 1 1 1 1 BED zinc finger NinB PF05772.7 KZN87643.1 - 0.11 12.0 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 NinB protein MFS_1 PF07690.11 KZN87644.1 - 3.3e-38 131.3 42.3 3.3e-38 131.3 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87644.1 - 5.3e-10 38.4 17.2 5.3e-10 38.4 11.9 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter Spc7_N PF15402.1 KZN87644.1 - 0.044 11.7 0.0 0.061 11.3 0.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1689 PF07954.6 KZN87644.1 - 0.51 10.1 2.0 4.8 7.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1689) RINGv PF12906.2 KZN87645.1 - 0.0018 18.2 3.4 0.0027 17.7 2.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN87645.1 - 0.082 12.7 3.4 0.14 11.9 2.4 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KZN87645.1 - 0.62 10.0 3.4 0.95 9.4 2.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain Ank_2 PF12796.2 KZN87646.1 - 1.3e-74 246.5 10.8 8.6e-16 58.0 0.0 5.2 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87646.1 - 1.6e-47 156.9 10.9 1.5e-06 27.6 0.0 10.6 10 0 0 10 10 10 10 Ankyrin repeat Ank_5 PF13857.1 KZN87646.1 - 2.7e-43 145.0 14.4 2.1e-09 37.3 0.0 8.9 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87646.1 - 6.5e-40 134.8 15.7 7.6e-08 32.6 0.1 7.4 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87646.1 - 4.3e-39 128.6 9.6 7.1e-05 22.6 0.0 10.8 11 0 0 11 11 11 9 Ankyrin repeat F-box-like PF12937.2 KZN87646.1 - 2.9e-05 23.6 0.3 6e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN87646.1 - 0.0022 17.6 0.2 0.0022 17.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain gag_pre-integrs PF13976.1 KZN87647.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Ank_5 PF13857.1 KZN87648.1 - 1.6e-60 199.7 11.7 1.6e-11 44.0 0.0 8.4 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN87648.1 - 1.2e-56 188.9 3.9 6.4e-20 71.2 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87648.1 - 9.3e-52 170.3 6.1 4e-06 26.3 0.0 9.6 9 1 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 KZN87648.1 - 2.6e-47 154.0 0.1 2.4e-05 24.1 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KZN87648.1 - 6.8e-41 137.9 0.0 4.1e-09 36.7 0.0 6.3 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Avirulence PF03377.8 KZN87648.1 - 0.00017 20.4 2.2 0.00021 20.1 1.5 1.2 1 0 0 1 1 1 1 Xanthomonas avirulence protein, Avr/PthA DUF3881 PF12997.2 KZN87648.1 - 0.00078 18.5 1.0 7.4 5.4 0.0 4.0 2 1 3 5 5 5 2 Domain of unknown function, E. rectale Gene description (DUF3881) LLGL PF08366.8 KZN87648.1 - 0.0047 16.8 0.1 39 4.2 0.0 3.5 3 0 0 3 3 3 0 LLGL2 Pyr_redox_3 PF13738.1 KZN87650.1 - 1.5e-26 93.7 0.1 3.5e-26 92.5 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN87650.1 - 2e-13 49.9 0.1 3.5e-10 39.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN87650.1 - 2.9e-12 46.9 0.0 1.5e-09 38.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN87650.1 - 8e-12 44.1 0.2 1.9e-10 39.5 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 KZN87650.1 - 1.3e-07 31.9 1.0 0.022 15.1 0.1 4.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KZN87650.1 - 6.3e-07 29.5 0.2 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KZN87650.1 - 1.3e-05 25.0 0.2 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN87650.1 - 2.6e-05 23.2 3.7 0.023 13.6 0.0 4.3 5 0 0 5 5 5 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KZN87650.1 - 3.1e-05 23.1 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KZN87650.1 - 8.8e-05 22.3 0.8 2.4 7.8 0.1 4.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KZN87650.1 - 0.00013 21.1 2.2 0.0027 16.7 0.3 2.5 2 1 1 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 KZN87650.1 - 0.00026 20.6 0.1 0.041 13.5 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KZN87650.1 - 0.00039 20.6 0.0 0.16 12.2 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding F420_oxidored PF03807.12 KZN87650.1 - 0.0012 19.2 0.0 0.51 10.8 0.0 3.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.19 KZN87650.1 - 0.0021 17.0 0.5 0.0089 14.9 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain ThiF PF00899.16 KZN87650.1 - 0.0039 17.0 1.6 0.67 9.7 0.1 2.3 2 0 0 2 2 2 1 ThiF family IlvN PF07991.7 KZN87650.1 - 0.0051 16.2 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 KZN87650.1 - 0.0076 15.1 0.5 3.1 6.5 0.1 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KZN87650.1 - 0.0096 15.5 0.1 0.99 8.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 KZN87650.1 - 0.012 15.9 0.0 0.061 13.6 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 KZN87650.1 - 0.015 15.0 0.5 6.8 6.4 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KZN87650.1 - 0.017 14.0 0.9 0.15 10.9 0.0 2.8 3 1 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.13 KZN87650.1 - 0.043 13.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.16 KZN87650.1 - 0.049 13.1 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KZN87650.1 - 0.097 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 KZN87652.1 - 2.3e-07 30.6 7.4 4.6e-07 29.6 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN87652.1 - 3.2e-07 29.3 1.3 5.4e-07 28.5 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2773 PF10971.3 KZN87652.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Caps_synth PF05704.7 KZN87653.1 - 1.6e-08 34.0 0.0 5.5e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KZN87653.1 - 6.8e-05 23.1 0.1 0.00018 21.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 4HBT_3 PF13622.1 KZN87654.1 - 1.5e-27 96.9 0.0 1.9e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily AAA PF00004.24 KZN87655.1 - 6.6e-17 61.9 0.0 1.5e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN87655.1 - 0.00036 21.3 0.1 0.0036 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN87655.1 - 0.0045 16.7 0.1 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN87655.1 - 0.0063 16.5 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN87655.1 - 0.0076 16.3 1.6 3.1 7.9 0.5 3.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN87655.1 - 0.075 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KZN87655.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein HSDR_N_2 PF13588.1 KZN87656.1 - 0.01 15.6 0.1 0.072 12.8 0.0 2.2 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Radial_spoke_3 PF06098.6 KZN87656.1 - 0.016 14.1 11.1 0.027 13.5 6.9 1.9 2 0 0 2 2 2 0 Radial spoke protein 3 Mnd1 PF03962.10 KZN87656.1 - 3.4 7.2 8.6 6.5 6.3 6.0 1.5 1 0 0 1 1 1 0 Mnd1 family DUF4629 PF15442.1 KZN87656.1 - 3.9 7.5 9.5 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Dimer_Tnp_hAT PF05699.9 KZN87658.1 - 9.7e-10 37.9 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4355 PF14265.1 KZN87662.1 - 0.0044 16.9 2.6 0.0054 16.6 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) CENP-Q PF13094.1 KZN87662.1 - 0.043 13.8 6.8 0.063 13.3 4.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.7 KZN87662.1 - 0.14 10.5 2.4 0.16 10.3 1.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 KZN87662.1 - 2.1 7.3 8.4 2.3 7.2 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyIII PF03006.15 KZN87664.1 - 0.24 10.7 11.7 0.32 10.3 8.1 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF3723 PF12520.3 KZN87665.1 - 2.1e-13 49.6 0.0 2.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF3723 PF12520.3 KZN87666.1 - 1.6e-33 115.9 0.2 1.8e-27 96.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF2706 PF10913.3 KZN87667.1 - 0.56 9.8 2.6 0.95 9.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2706) Prok-JAB PF14464.1 KZN87670.1 - 0.00061 19.3 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.1 KZN87670.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 JAB-like toxin 1 Patatin PF01734.17 KZN87673.1 - 3.4e-21 76.1 0.8 8.5e-21 74.8 0.2 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 KZN87673.1 - 0.004 17.1 9.9 0.013 15.5 6.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN87673.1 - 0.006 16.2 7.4 0.017 14.8 5.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN87673.1 - 0.0074 15.9 8.4 0.024 14.2 5.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN87673.1 - 0.14 11.9 9.2 0.42 10.4 6.4 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 KZN87673.1 - 0.61 9.6 6.4 4.8 6.7 2.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FxsA PF04186.8 KZN87674.1 - 0.079 12.5 1.7 2.1 7.9 0.0 2.7 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Pkinase PF00069.20 KZN87675.1 - 1.6e-05 24.2 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87675.1 - 0.029 13.4 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 KZN87680.1 - 4.9e-67 222.2 7.6 4.1e-14 52.6 0.0 5.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87680.1 - 2.4e-44 146.9 15.9 6.7e-07 28.8 0.0 10.3 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 KZN87680.1 - 5.2e-40 134.5 13.6 5.9e-10 39.0 0.0 8.8 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87680.1 - 7.6e-38 128.2 14.6 5.3e-08 33.1 0.0 7.7 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87680.1 - 6.1e-33 109.5 12.5 0.00097 19.1 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat F-box-like PF12937.2 KZN87680.1 - 0.00039 20.0 0.1 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN87680.1 - 0.03 13.9 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain zf-RING_2 PF13639.1 KZN87681.1 - 0.001 18.8 8.9 0.0019 17.9 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN87681.1 - 0.0024 17.8 9.4 0.005 16.8 6.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN87681.1 - 0.0083 16.2 3.4 0.019 15.0 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN87681.1 - 0.98 9.5 7.5 2.1 8.4 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN87682.1 - 3.9e-24 84.8 0.0 1e-11 44.9 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87682.1 - 1.9e-10 40.9 0.0 6.7e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN87682.1 - 4.4e-10 38.8 0.0 1.2e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KZN87682.1 - 5.9e-09 35.3 0.0 2.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KZN87682.1 - 8.3e-09 35.4 0.1 2.1e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Apolipoprotein PF01442.13 KZN87687.1 - 0.052 13.0 1.0 0.093 12.2 0.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2236 PF09995.4 KZN87687.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Kdo PF06293.9 KZN87688.1 - 0.00075 18.6 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KZN87688.1 - 0.0025 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN87688.1 - 0.0098 15.6 0.2 0.022 14.4 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN87688.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KZN87688.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-RING_2 PF13639.1 KZN87689.1 - 0.001 18.8 9.0 0.0016 18.2 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN87689.1 - 0.0022 18.0 9.8 0.0041 17.1 6.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN87689.1 - 0.012 15.7 4.0 0.022 14.8 2.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN87689.1 - 0.042 13.7 0.1 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN87689.1 - 1.4 8.9 7.8 2.7 8.1 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Chibby PF14645.1 KZN87690.1 - 0.074 12.9 0.1 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Chibby family Senescence_reg PF04520.8 KZN87691.1 - 0.079 13.4 0.1 0.079 13.4 0.1 1.0 1 0 0 1 1 1 0 Senescence regulator CitX PF03802.9 KZN87692.1 - 0.1 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase UPF0278 PF08745.6 KZN87693.1 - 0.015 14.5 4.1 0.096 11.9 2.9 1.9 1 1 0 1 1 1 0 UPF0278 family Cornifin PF02389.10 KZN87693.1 - 0.054 13.2 0.4 0.077 12.7 0.3 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family TryThrA_C PF12319.3 KZN87693.1 - 0.096 11.8 7.3 0.28 10.3 5.1 1.7 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ACP PF06857.6 KZN87693.1 - 0.58 10.1 6.3 1.3e+02 2.5 4.4 2.7 1 1 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Chordopox_G3 PF06129.7 KZN87693.1 - 0.65 10.1 9.9 2.9e+02 1.6 6.8 2.6 1 1 0 1 1 1 0 Chordopoxvirus G3 protein SVA PF05326.6 KZN87693.1 - 2.3 7.9 11.1 4 7.2 6.5 1.8 1 1 1 2 2 2 0 Seminal vesicle autoantigen (SVA) PDGF_N PF04692.8 KZN87694.1 - 0.032 14.7 2.7 0.045 14.2 0.3 2.3 2 2 0 2 2 2 0 Platelet-derived growth factor, N terminal region PTS_IIB PF02302.12 KZN87695.1 - 0.3 11.5 1.2 0.46 11.0 0.8 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit IncA PF04156.9 KZN87695.1 - 1.4 8.4 8.3 2.1 7.9 5.7 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KZN87695.1 - 2 7.3 6.7 2.2 7.2 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3723 PF12520.3 KZN87699.1 - 1.1e-59 202.2 0.0 5.3e-54 183.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF2706 PF10913.3 KZN87700.1 - 0.3 10.7 2.5 0.72 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Sarcoglycan_1 PF04790.8 KZN87702.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Patatin PF01734.17 KZN87704.1 - 2.6e-22 79.7 0.4 7.7e-22 78.2 0.3 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.1 KZN87704.1 - 0.074 12.7 10.8 0.21 11.3 7.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN87704.1 - 0.087 12.4 11.5 0.27 10.9 8.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN87704.1 - 0.13 12.2 13.4 0.42 10.6 9.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN87704.1 - 0.79 9.5 12.4 2.3 8.1 8.6 1.9 1 0 0 1 1 1 0 Ring finger domain rve PF00665.21 KZN87705.1 - 5.2e-24 84.6 0.1 1.1e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.1 KZN87705.1 - 4.3e-09 35.5 0.1 1.3e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KZN87705.1 - 5.1e-06 26.1 0.0 0.05 13.1 0.0 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KZN87705.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KZN87705.1 - 8.6e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 KZN87705.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 KZN87705.1 - 0.006 16.0 0.0 0.02 14.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 KZN87705.1 - 0.011 15.6 4.7 0.032 14.1 3.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Pyr_redox_2 PF07992.9 KZN87707.1 - 1.2e-20 74.3 0.0 2.3e-20 73.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN87707.1 - 4.2e-14 52.7 0.0 5.5e-12 45.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KZN87707.1 - 7.2e-06 26.0 0.1 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KZN87707.1 - 1.2e-05 24.1 0.1 4.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KZN87707.1 - 0.00016 21.2 0.1 0.0005 19.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KZN87707.1 - 0.00048 19.3 0.1 0.0029 16.8 0.0 2.2 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 KZN87707.1 - 0.074 13.0 0.1 5.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.4 KZN87708.1 - 9.4e-24 83.7 0.1 1.3e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C2H2 PF00096.21 KZN87709.1 - 1.2e-05 25.3 9.1 0.016 15.4 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN87709.1 - 8.2e-05 22.7 0.1 8.2e-05 22.7 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN87709.1 - 0.00068 19.7 7.4 0.073 13.4 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Ank_4 PF13637.1 KZN87710.1 - 3.1e-49 164.5 0.0 2.6e-10 40.5 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN87710.1 - 1.7e-47 159.6 0.0 4.6e-20 71.7 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87710.1 - 7.9e-46 151.6 0.0 1.7e-06 27.5 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KZN87710.1 - 1.6e-39 132.9 0.0 1.1e-07 31.8 0.0 5.5 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87710.1 - 6.5e-38 124.9 0.0 0.00015 21.6 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat DUF2256 PF10013.4 KZN87710.1 - 0.11 12.2 0.3 0.69 9.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RNase_P_p30 PF01876.11 KZN87710.1 - 0.14 11.4 0.0 8.1 5.6 0.0 3.2 2 2 2 4 4 4 0 RNase P subunit p30 HALZ PF02183.13 KZN87711.1 - 0.0023 17.6 1.9 0.023 14.3 0.6 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF904 PF06005.7 KZN87711.1 - 0.029 14.6 9.2 0.096 12.9 3.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) NUDE_C PF04880.8 KZN87711.1 - 0.061 13.6 6.9 0.24 11.7 0.6 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region DUF342 PF03961.8 KZN87711.1 - 0.072 11.4 2.0 0.098 11.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 KZN87711.1 - 0.27 10.7 4.2 0.68 9.4 2.3 2.2 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KZN87711.1 - 0.33 9.9 8.2 0.018 14.0 2.1 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 KZN87711.1 - 0.38 10.5 13.4 0.41 10.4 6.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 KZN87711.1 - 0.83 9.5 5.2 1.5 8.7 1.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF2205 PF10224.4 KZN87711.1 - 0.86 9.2 4.7 0.73 9.4 1.8 2.0 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DMPK_coil PF08826.5 KZN87711.1 - 1.9 8.4 7.9 5.8 6.8 3.8 2.7 2 1 0 2 2 2 0 DMPK coiled coil domain like DUF972 PF06156.8 KZN87711.1 - 3.5 8.0 7.5 0.5 10.7 1.0 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KZN87711.1 - 7 6.1 10.5 1.9 8.0 4.8 1.7 1 1 0 2 2 2 0 IncA protein Uso1_p115_C PF04871.8 KZN87711.1 - 7.4 6.5 11.3 0.68 9.8 3.0 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Thioredoxin_4 PF13462.1 KZN87712.1 - 0.00014 21.9 0.0 0.00023 21.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DUF1242 PF06842.7 KZN87713.1 - 0.1 12.0 15.1 99 2.5 0.1 7.6 1 1 11 12 12 12 0 Protein of unknown function (DUF1242) Pro-rich PF15240.1 KZN87713.1 - 0.59 10.2 20.4 8.4 6.4 14.1 2.0 1 1 0 1 1 1 0 Proline-rich MARVEL PF01284.18 KZN87714.1 - 4e-07 29.9 3.8 5.2e-07 29.5 2.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain E1-E2_ATPase PF00122.15 KZN87715.1 - 1.7e-71 239.8 8.0 1.2e-70 237.1 0.3 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KZN87715.1 - 7.7e-26 91.8 0.1 1.8e-25 90.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN87715.1 - 4.9e-16 59.4 0.0 9.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN87715.1 - 9.6e-10 37.7 0.0 2.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN87715.1 - 0.0012 18.4 1.8 0.023 14.2 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN87715.1 - 0.002 18.0 0.0 0.0063 16.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TRAP_beta PF05753.9 KZN87715.1 - 0.041 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) GNVR PF13807.1 KZN87715.1 - 0.33 10.7 1.8 0.62 9.8 0.0 2.5 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Ank_2 PF12796.2 KZN87719.1 - 2.9e-24 85.1 0.0 1e-11 44.9 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87719.1 - 1.9e-10 40.9 0.0 6.7e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN87719.1 - 4.3e-10 38.8 0.0 1.2e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KZN87719.1 - 5.9e-09 35.3 0.0 2.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KZN87719.1 - 7.1e-09 35.6 0.1 2.1e-06 27.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Kdo PF06293.9 KZN87720.1 - 4.5e-06 25.8 0.0 9.5e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN87720.1 - 0.00011 21.4 0.1 0.00026 20.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN87720.1 - 0.0043 16.8 0.1 0.0043 16.8 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family SRF-TF PF00319.13 KZN87721.1 - 0.04 13.1 0.1 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) SufE PF02657.10 KZN87721.1 - 0.057 13.0 0.1 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Fe-S metabolism associated domain Elf1 PF05129.8 KZN87721.1 - 0.067 12.8 0.7 0.087 12.5 0.5 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_clus PF00172.13 KZN87724.1 - 4.7e-08 32.8 16.2 7.1e-08 32.2 1.8 3.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain YlzJ PF14035.1 KZN87724.1 - 0.12 12.3 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 YlzJ-like protein zf-XS PF03470.9 KZN87725.1 - 1.2e-05 25.2 0.1 1e+02 3.0 0.0 6.1 6 0 0 6 6 6 0 XS zinc finger domain AcetylCoA_hyd_C PF13336.1 KZN87725.1 - 0.042 13.5 0.2 48 3.5 0.0 3.9 1 1 4 5 5 5 0 Acetyl-CoA hydrolase/transferase C-terminal domain PSI PF01437.20 KZN87726.1 - 0.24 11.5 1.7 0.53 10.4 1.2 1.6 1 1 0 1 1 1 0 Plexin repeat DUF4219 PF13961.1 KZN87727.1 - 3.3e-09 35.9 0.5 7.5e-09 34.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 KZN87727.1 - 1.6e-06 27.8 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN87727.1 - 0.0013 18.2 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KZN87727.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 KZN87727.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Ank_2 PF12796.2 KZN87728.1 - 8.1e-56 186.3 2.3 3.6e-17 62.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87728.1 - 5.5e-52 171.0 0.4 4.1e-08 32.6 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KZN87728.1 - 5.9e-40 134.9 6.1 2.4e-09 37.4 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN87728.1 - 1.4e-37 126.8 3.0 1.7e-11 43.9 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87728.1 - 1.2e-36 121.1 0.1 6.6e-07 28.9 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat F-box PF00646.28 KZN87728.1 - 0.00022 20.7 0.4 0.0005 19.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain Shigella_OspC PF06128.6 KZN87728.1 - 0.0019 17.7 0.2 0.95 8.9 0.1 3.4 2 2 2 4 4 4 1 Shigella flexneri OspC protein F-box-like PF12937.2 KZN87728.1 - 0.014 15.0 0.2 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Pribosyltran PF00156.22 KZN87729.1 - 1e-16 60.7 0.0 1.4e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KZN87729.1 - 7.2e-05 22.0 0.0 9.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KZN87729.1 - 0.0086 15.3 0.0 0.0099 15.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase PRTase_3 PF15610.1 KZN87729.1 - 0.17 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like zf-C2H2 PF00096.21 KZN87730.1 - 1.3e-05 25.2 8.6 0.01 16.1 0.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87730.1 - 7.7e-05 22.7 7.6 0.021 15.1 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN87730.1 - 8.4e-05 22.6 0.1 8.4e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Ank_2 PF12796.2 KZN87731.1 - 1.1e-89 294.8 14.0 3.2e-14 53.0 0.1 6.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87731.1 - 3.3e-64 209.6 10.7 2.1e-07 30.4 0.0 13.4 13 0 0 13 13 13 13 Ankyrin repeat Ank_3 PF13606.1 KZN87731.1 - 1.5e-47 154.8 4.2 0.00022 21.1 0.0 12.9 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 KZN87731.1 - 2.6e-47 158.3 7.4 3.2e-07 30.6 0.0 10.4 3 3 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN87731.1 - 6.2e-33 112.0 11.7 2.2e-07 30.9 0.0 8.9 5 4 5 10 10 10 8 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN87731.1 - 1.5e-05 24.5 1.0 2.4e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like zf-C2H2 PF00096.21 KZN87732.1 - 0.00013 22.0 10.0 0.048 14.0 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87732.1 - 0.00024 21.2 8.7 0.039 14.3 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN87732.1 - 0.00037 20.6 0.2 0.00037 20.6 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain APH PF01636.18 KZN87733.1 - 2.4e-05 24.1 0.2 4.5e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN87733.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DRIM PF07539.7 KZN87733.1 - 0.028 13.8 0.1 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis Mitofilin PF09731.4 KZN87736.1 - 0.054 12.1 1.1 0.13 10.9 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Ank_2 PF12796.2 KZN87738.1 - 4.5e-76 251.2 17.4 2.2e-13 50.3 0.0 5.7 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87738.1 - 8.3e-48 157.9 21.2 9.1e-07 28.3 0.0 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KZN87738.1 - 4.6e-42 141.0 20.0 6.6e-10 38.9 0.1 10.1 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87738.1 - 4.5e-41 138.5 16.4 4.4e-08 33.4 0.0 8.1 3 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87738.1 - 3.2e-36 119.7 13.4 6.7e-05 22.7 0.0 11.2 11 0 0 11 11 11 8 Ankyrin repeat F-box-like PF12937.2 KZN87738.1 - 0.0034 17.0 0.1 0.0066 16.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like UBN2_2 PF14227.1 KZN87740.1 - 1.6e-13 50.2 0.3 2.9e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KZN87740.1 - 2.2e-12 46.8 0.4 4.3e-12 45.8 0.3 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN87740.1 - 4.5e-05 23.0 1.1 0.044 13.3 0.3 2.6 1 1 2 3 3 3 2 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 KZN87740.1 - 0.0002 21.3 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1759 PF03564.10 KZN87740.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Ras PF00071.17 KZN87741.1 - 2.1e-38 131.2 0.0 5.1e-38 130.0 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN87741.1 - 3.4e-12 46.8 0.0 8.2e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN87741.1 - 6e-05 22.9 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ank_2 PF12796.2 KZN87743.1 - 2.7e-13 50.0 0.0 3.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87743.1 - 4e-11 42.1 0.1 9.2e-08 31.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN87743.1 - 7.4e-10 38.7 0.2 5.7e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87743.1 - 1.8e-09 37.8 0.1 7.6e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87743.1 - 1.4e-06 27.9 0.0 0.00059 19.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Dimer_Tnp_hAT PF05699.9 KZN87744.1 - 8e-12 44.6 0.0 2.7e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KZN87744.1 - 0.038 13.9 0.9 0.089 12.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Fic_N PF13784.1 KZN87744.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Fic/DOC family N-terminal SURF2 PF05477.6 KZN87744.1 - 0.19 10.8 5.3 0.45 9.6 3.7 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.5 KZN87744.1 - 0.63 9.0 7.9 1.1 8.2 5.5 1.3 1 0 0 1 1 1 0 BUD22 Virul_fac_BrkB PF03631.10 KZN87745.1 - 0.022 14.1 1.6 0.034 13.4 1.1 1.2 1 0 0 1 1 1 0 Virulence factor BrkB RbsD_FucU PF05025.8 KZN87747.1 - 0.0098 16.2 0.1 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 RbsD / FucU transport protein family Sigma70_ner PF04546.8 KZN87747.1 - 0.057 13.0 4.3 0.07 12.7 3.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Dimer_Tnp_hAT PF05699.9 KZN87748.1 - 8.9e-11 41.2 0.1 5.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KZN87748.1 - 1.1e-05 25.1 3.1 2.6e-05 23.8 2.2 1.6 1 0 0 1 1 1 1 BED zinc finger Kdo PF06293.9 KZN87749.1 - 4.8e-06 25.7 0.0 9.5e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN87749.1 - 0.0001 21.5 0.2 0.00026 20.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN87749.1 - 0.0043 16.8 0.1 0.0043 16.8 0.1 3.7 3 1 1 4 4 4 1 Phosphotransferase enzyme family CDC45 PF02724.9 KZN87749.1 - 8.8 4.2 5.7 1.4 6.8 1.2 1.6 2 0 0 2 2 2 0 CDC45-like protein Ank_2 PF12796.2 KZN87750.1 - 2.2e-31 108.0 1.2 5.9e-17 61.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87750.1 - 1.5e-18 66.7 1.2 1.7e-09 37.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN87750.1 - 1.8e-16 59.0 1.1 1.2e-08 34.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN87750.1 - 5.7e-16 58.1 1.5 4.4e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87750.1 - 1.7e-13 49.3 0.6 2.2e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_2 PF13639.1 KZN87752.1 - 0.00075 19.2 8.9 0.0013 18.5 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN87752.1 - 0.0017 18.3 9.8 0.0034 17.3 6.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN87752.1 - 0.011 15.8 3.9 0.024 14.7 2.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN87752.1 - 0.032 14.0 0.1 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN87752.1 - 1.1 9.3 7.8 2.3 8.3 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN87753.1 - 2.6e-67 223.1 13.1 6.6e-16 58.4 0.0 6.1 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN87753.1 - 3.6e-48 159.0 23.5 6.1e-07 28.9 0.0 12.4 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KZN87753.1 - 3.9e-47 157.2 20.8 6.8e-09 35.6 0.1 10.4 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN87753.1 - 1.2e-43 146.7 17.0 9.2e-07 29.2 0.0 8.7 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87753.1 - 2.5e-38 126.2 15.0 0.00042 20.2 0.0 12.3 12 0 0 12 12 12 9 Ankyrin repeat F-box-like PF12937.2 KZN87753.1 - 8.9e-05 22.1 0.2 0.00017 21.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN87753.1 - 0.00019 20.9 0.2 0.00045 19.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain SlyX PF04102.7 KZN87755.1 - 0.016 15.5 1.5 0.16 12.3 0.1 2.5 2 0 0 2 2 2 0 SlyX TerB PF05099.8 KZN87755.1 - 0.08 12.6 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TerB Na_H_Exchanger PF00999.16 KZN87756.1 - 8e-40 136.5 26.9 1.8e-39 135.3 18.6 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family CP2 PF04516.10 KZN87758.1 - 8.8e-15 54.4 0.0 1.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor adh_short PF00106.20 KZN87760.1 - 1.6e-26 93.2 0.7 2.2e-26 92.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87760.1 - 5.4e-22 78.7 0.1 6.7e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87760.1 - 8.8e-12 45.0 0.4 1.4e-11 44.4 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 KZN87760.1 - 0.012 15.4 0.1 0.47 10.2 0.0 2.6 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Dimer_Tnp_hAT PF05699.9 KZN87761.1 - 8.7e-08 31.6 0.0 2.4e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region NEMO PF11577.3 KZN87763.1 - 1.1 9.0 6.8 3.8 7.3 4.7 1.8 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO Chibby PF14645.1 KZN87764.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Chibby family RINGv PF12906.2 KZN87765.1 - 0.00061 19.7 4.2 0.0011 18.9 2.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN87765.1 - 0.042 13.6 4.3 0.074 12.9 3.0 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KZN87765.1 - 0.46 10.4 3.0 0.8 9.7 2.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Dimer_Tnp_hAT PF05699.9 KZN87766.1 - 8.9e-11 41.2 0.0 5e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KZN87766.1 - 1.3e-07 31.4 0.0 4.1e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-RanBP PF00641.13 KZN87769.1 - 0.011 14.8 0.2 0.014 14.4 0.1 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Shisa PF13908.1 KZN87773.1 - 4.4 7.4 5.4 12 6.0 3.4 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Ank_2 PF12796.2 KZN87774.1 - 3.2e-60 200.4 4.0 8e-16 58.1 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87774.1 - 1.2e-46 156.2 10.1 1.1e-08 35.2 0.0 8.5 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 KZN87774.1 - 2.4e-44 146.9 18.6 2.1e-07 30.4 0.0 12.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 KZN87774.1 - 7.6e-39 130.8 15.8 1.2e-10 41.3 0.0 10.0 5 5 6 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87774.1 - 4.9e-38 125.3 13.5 1.5e-05 24.8 0.0 12.5 13 0 0 13 13 13 9 Ankyrin repeat F-box PF00646.28 KZN87774.1 - 0.031 13.9 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KZN87774.1 - 0.056 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 F-box-like Chibby PF14645.1 KZN87775.1 - 0.24 11.2 2.4 0.17 11.7 0.3 1.6 2 0 0 2 2 2 0 Chibby family DUF4064 PF13273.1 KZN87777.1 - 0.54 10.3 6.2 2.7 8.1 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) CD20 PF04103.10 KZN87777.1 - 2.3 8.1 9.1 9.4 6.1 0.1 2.7 2 1 0 2 2 2 0 CD20-like family Tetraspannin PF00335.15 KZN87777.1 - 2.5 7.3 10.4 0.22 10.7 3.3 1.8 1 1 1 2 2 2 0 Tetraspanin family VIT1 PF01988.14 KZN87777.1 - 3 7.2 8.5 0.061 12.7 1.2 1.7 2 0 0 2 2 2 0 VIT family Ank_2 PF12796.2 KZN87778.1 - 8.7e-34 115.7 0.1 2.4e-18 66.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87778.1 - 6.3e-19 67.9 0.2 4.7e-09 36.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN87778.1 - 9.2e-17 59.9 0.2 1.3e-09 37.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN87778.1 - 5.7e-15 55.0 3.1 6.2e-09 35.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87778.1 - 2.8e-13 48.6 0.1 6.5e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Dimer_Tnp_hAT PF05699.9 KZN87780.1 - 1.7e-10 40.3 0.0 4.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KZN87780.1 - 1.1e-05 25.1 3.1 2.6e-05 23.8 2.2 1.6 1 0 0 1 1 1 1 BED zinc finger RbsD_FucU PF05025.8 KZN87781.1 - 0.0038 17.5 0.1 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 RbsD / FucU transport protein family Sigma70_ner PF04546.8 KZN87781.1 - 0.028 14.0 3.4 0.034 13.7 2.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Virul_fac_BrkB PF03631.10 KZN87783.1 - 0.01 15.2 1.0 0.015 14.6 0.7 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Mitofilin PF09731.4 KZN87784.1 - 0.044 12.4 0.5 0.071 11.7 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein zf-C2H2 PF00096.21 KZN87785.1 - 3.2e-06 27.1 18.8 0.0014 18.8 2.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN87785.1 - 1.4e-05 25.0 3.2 1.4e-05 25.0 2.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN87785.1 - 0.00024 21.1 10.3 0.058 13.7 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger ZF-HD_dimer PF04770.7 KZN87785.1 - 0.17 11.9 4.0 0.25 11.4 0.3 2.4 1 1 1 2 2 2 0 ZF-HD protein dimerisation region zf-met PF12874.2 KZN87785.1 - 0.5 10.6 10.2 3.5 7.9 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RasGEF PF00617.14 KZN87787.1 - 7.5e-05 22.5 0.6 0.0024 17.6 0.1 3.3 2 1 0 2 2 2 1 RasGEF domain Pkinase PF00069.20 KZN87795.1 - 3.6e-07 29.6 0.0 7.8e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87795.1 - 0.023 13.7 0.0 0.072 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Aida_C2 PF14186.1 KZN87797.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal adhesion DUF4219 PF13961.1 KZN87798.1 - 1.6e-08 33.7 0.7 2.8e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 KZN87798.1 - 2.2e-06 27.4 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN87798.1 - 3.9e-06 26.4 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KZN87798.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KZN87798.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain rve_3 PF13683.1 KZN87798.1 - 0.055 12.9 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 KZN87798.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain NEMO PF11577.3 KZN87799.1 - 0.94 9.2 5.6 3.7 7.3 3.9 1.9 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO zf-H2C2_2 PF13465.1 KZN87803.1 - 1.5e-05 25.0 3.2 1.5e-05 25.0 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KZN87803.1 - 6.8e-05 22.9 18.5 0.00097 19.3 1.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN87803.1 - 0.0021 18.2 9.0 0.042 14.1 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger RasGEF PF00617.14 KZN87804.1 - 5.2e-05 23.0 1.3 0.0044 16.7 0.0 3.5 2 1 1 3 3 3 1 RasGEF domain RINGv PF12906.2 KZN87806.1 - 0.00034 20.5 6.6 0.00065 19.6 4.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN87806.1 - 0.00066 19.4 8.4 0.0011 18.7 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN87806.1 - 0.01 15.8 3.2 0.02 14.9 2.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN87806.1 - 0.054 13.3 0.1 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN87806.1 - 0.72 9.9 7.2 1.4 9.0 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CitX PF03802.9 KZN87809.1 - 0.14 11.5 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase RHD3 PF05879.7 KZN87810.1 - 0.025 12.5 1.5 0.043 11.7 1.0 1.3 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Cornifin PF02389.10 KZN87810.1 - 0.11 12.2 0.3 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family TryThrA_C PF12319.3 KZN87810.1 - 0.12 11.5 10.5 1 8.4 7.4 1.9 1 1 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF3227 PF11537.3 KZN87810.1 - 0.36 10.9 2.7 59 3.8 1.9 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3227) Chordopox_G3 PF06129.7 KZN87810.1 - 0.68 10.1 10.4 4.5e+02 1.0 7.2 2.7 1 1 0 1 1 1 0 Chordopoxvirus G3 protein ACP PF06857.6 KZN87810.1 - 2.3 8.2 6.7 2.8e+02 1.4 4.7 2.8 1 1 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) MatP PF06303.7 KZN87810.1 - 5.5 6.8 10.8 8.3e+02 -0.2 7.5 2.5 1 1 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome CENP-T PF15511.1 KZN87812.1 - 0.037 13.2 5.3 0.041 13.1 3.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 KZN87812.1 - 0.5 8.3 3.8 0.53 8.2 2.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Sua5_yciO_yrdC PF01300.13 KZN87813.1 - 6.9e-13 48.2 0.0 1e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 Telomere recombination Kdo PF06293.9 KZN87814.1 - 0.00068 18.7 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KZN87814.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN87814.1 - 0.0089 15.7 0.2 0.019 14.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN87814.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KZN87814.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Elf1 PF05129.8 KZN87816.1 - 0.082 12.6 0.4 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Kdo PF06293.9 KZN87817.1 - 4.3e-06 25.9 0.0 8.6e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN87817.1 - 0.00032 19.9 0.1 0.00082 18.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN87817.1 - 0.0037 17.0 0.1 0.0037 17.0 0.0 3.7 3 1 1 4 4 4 1 Phosphotransferase enzyme family Spore_coat_CotO PF14153.1 KZN87817.1 - 0.0046 16.4 2.6 0.0072 15.7 1.8 1.3 1 0 0 1 1 1 1 Spore coat protein CotO CDC45 PF02724.9 KZN87817.1 - 0.095 10.7 5.9 0.061 11.3 2.7 1.6 2 0 0 2 2 2 0 CDC45-like protein Ycf1 PF05758.7 KZN87817.1 - 0.26 8.9 1.7 0.33 8.6 1.2 1.1 1 0 0 1 1 1 0 Ycf1 ARGLU PF15346.1 KZN87817.1 - 2.5 7.8 31.5 4.7 6.9 21.8 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ank_2 PF12796.2 KZN87819.1 - 7e-71 234.6 18.4 1.3e-16 60.6 0.1 6.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN87819.1 - 6.2e-64 211.3 14.1 1.3e-11 44.6 0.1 8.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 KZN87819.1 - 1.7e-58 191.6 18.0 6.4e-07 28.8 0.2 10.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KZN87819.1 - 8.8e-55 181.5 33.3 1.1e-10 41.4 0.2 9.2 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87819.1 - 4.6e-50 162.5 11.8 3.3e-05 23.6 0.0 11.3 11 0 0 11 11 11 10 Ankyrin repeat Shigella_OspC PF06128.6 KZN87819.1 - 0.0069 15.9 0.1 0.1 12.1 0.1 3.2 2 2 1 3 3 3 1 Shigella flexneri OspC protein TolA PF06519.6 KZN87819.1 - 0.063 13.2 0.2 2.2 8.2 0.0 3.2 4 0 0 4 4 4 0 TolA C-terminal PSI PF01437.20 KZN87821.1 - 0.12 12.6 1.0 0.18 11.9 0.7 1.4 1 1 0 1 1 1 0 Plexin repeat APH PF01636.18 KZN87823.1 - 0.00016 21.4 0.7 0.00016 21.4 0.5 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN87823.1 - 0.0038 16.3 0.1 0.0088 15.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KZN87823.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 KZN87824.1 - 7.6e-31 106.9 1.0 1.1e-30 106.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87824.1 - 1.1e-06 28.4 8.7 2.3e-06 27.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KicB PF03882.9 KZN87824.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 KicB killing factor UPF0561 PF10573.4 KZN87824.1 - 0.27 11.0 1.3 0.58 10.0 0.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Cyt-b5 PF00173.23 KZN87825.1 - 1.9e-12 46.8 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 KZN87826.1 - 1.5e-70 238.0 0.0 1.8e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 KZN87827.1 - 3.3e-33 114.5 0.0 5.7e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN87827.1 - 3e-25 88.2 0.0 8.2e-25 86.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KZN87827.1 - 1.1e-22 79.6 0.5 1.9e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KZN87827.1 - 1.5e-06 28.2 0.0 0.0003 20.7 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KZN87827.1 - 0.024 14.6 0.0 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.13 KZN87828.1 - 1.4e-31 109.5 0.0 2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN87828.1 - 9.5e-10 38.7 0.0 2.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KZN87828.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KZN87828.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.7 KZN87828.1 - 0.023 14.0 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region 2-Hacid_dh_C PF02826.14 KZN87828.1 - 0.043 12.9 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN87828.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KZN87829.1 - 1.5e-41 142.0 0.0 2.1e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN87829.1 - 1.6e-09 38.0 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 KZN87829.1 - 0.00088 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN87829.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KZN87829.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN87829.1 - 0.088 13.2 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KZN87829.1 - 0.13 11.1 0.2 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_N PF08240.7 KZN87830.1 - 4.2e-18 65.1 0.0 1.2e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN87830.1 - 2.8e-08 33.3 0.9 2.4e-07 30.3 0.6 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KZN87830.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KZN87830.1 - 0.025 13.0 0.1 0.036 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ADH_N_assoc PF13823.1 KZN87830.1 - 0.064 12.9 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated 3HCDH_N PF02737.13 KZN87830.1 - 0.14 11.7 0.3 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KZN87831.1 - 2.1e-30 105.6 35.4 4.5e-30 104.5 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KZN87832.1 - 3.9e-28 98.4 0.0 5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN87832.1 - 1.9e-23 83.4 0.0 2.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN87832.1 - 5.9e-12 45.6 0.0 8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KZN87832.1 - 0.01 15.5 0.1 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KZN87832.1 - 0.047 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KZN87832.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 6PGD PF00393.14 KZN87833.1 - 4.4e-58 196.8 0.0 6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KZN87833.1 - 8.3e-36 123.2 0.0 1.5e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KZN87833.1 - 1.8e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KZN87833.1 - 2.9e-06 27.0 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN87833.1 - 0.00035 19.7 0.0 0.00066 18.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN87833.1 - 0.00035 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KZN87833.1 - 0.0022 18.3 0.0 0.0061 16.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KZN87833.1 - 0.0092 16.3 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 KZN87833.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KZN87833.1 - 0.018 15.0 0.0 0.071 13.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain XdhC_C PF13478.1 KZN87833.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 KZN87833.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding PMI_typeI PF01238.16 KZN87834.1 - 4.6e-14 52.1 0.1 2e-12 46.7 0.0 2.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I HisKA PF00512.20 KZN87837.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Epimerase PF01370.16 KZN87838.1 - 6.1e-22 78.2 0.0 8.5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN87838.1 - 7.6e-11 41.4 0.5 2.2e-07 30.0 0.0 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KZN87838.1 - 1.1e-08 34.3 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KZN87838.1 - 5.5e-08 32.0 0.2 3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KZN87838.1 - 0.00088 18.0 0.0 0.0037 16.0 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN87838.1 - 0.062 13.2 0.7 7.6 6.4 0.0 3.0 4 0 0 4 4 4 0 short chain dehydrogenase KR PF08659.5 KZN87838.1 - 1 8.9 3.2 11 5.6 0.0 2.8 2 1 0 3 3 3 0 KR domain FlgN PF05130.7 KZN87839.1 - 0.0049 17.1 2.7 0.013 15.7 1.6 1.9 1 1 0 1 1 1 1 FlgN protein Syntaxin-6_N PF09177.6 KZN87839.1 - 0.025 14.9 3.5 0.15 12.4 0.4 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MutS_III PF05192.13 KZN87839.1 - 0.034 13.9 5.2 0.052 13.3 3.6 1.4 1 1 0 1 1 1 0 MutS domain III Peptidase_M20 PF01546.23 KZN87839.1 - 0.087 12.3 0.0 9.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Striatin PF08232.7 KZN87839.1 - 0.088 13.1 3.9 0.1 12.8 0.1 2.5 3 0 0 3 3 3 0 Striatin family HAUS-augmin3 PF14932.1 KZN87839.1 - 0.093 11.8 3.7 1.3 8.1 0.0 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.7 KZN87839.1 - 0.11 12.7 0.8 4.4 7.6 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 KZN87839.1 - 1.1 9.6 7.0 4.1 7.8 0.2 3.0 3 0 0 3 3 3 0 SlyX bZIP_1 PF00170.16 KZN87843.1 - 7.7e-08 32.1 6.4 1.3e-07 31.4 4.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN87843.1 - 1.1e-07 31.6 7.3 2e-07 30.7 5.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper NUDE_C PF04880.8 KZN87843.1 - 0.03 14.6 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region bZIP_Maf PF03131.12 KZN87843.1 - 0.74 10.1 7.6 0.39 11.0 3.7 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor Herpes_capsid PF06112.6 KZN87844.1 - 0.18 11.8 4.9 0.3 11.1 3.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4625 PF15418.1 KZN87845.1 - 0.0014 18.7 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) Chitin_bind_3 PF03067.10 KZN87845.1 - 0.023 14.9 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Chitin binding domain MAPKK1_Int PF08923.5 KZN87847.1 - 0.0078 15.8 0.1 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF972 PF06156.8 KZN87848.1 - 0.00048 20.4 1.0 0.00086 19.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF1664 PF07889.7 KZN87848.1 - 0.0022 17.8 1.1 0.0034 17.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 KZN87848.1 - 0.0072 14.1 1.2 0.01 13.6 0.8 1.1 1 0 0 1 1 1 1 Myosin tail TSC22 PF01166.13 KZN87848.1 - 0.0083 16.0 0.7 0.015 15.2 0.5 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Tmemb_cc2 PF10267.4 KZN87848.1 - 0.01 14.4 0.2 0.013 14.0 0.2 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein FlxA PF14282.1 KZN87848.1 - 0.014 15.3 4.0 0.022 14.7 2.7 1.4 1 0 0 1 1 1 0 FlxA-like protein ATG16 PF08614.6 KZN87848.1 - 0.017 14.9 1.4 0.017 14.9 1.0 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4527 PF15030.1 KZN87848.1 - 0.024 13.9 1.5 0.024 13.9 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) IncA PF04156.9 KZN87848.1 - 0.025 14.1 1.4 0.034 13.7 1.0 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 KZN87848.1 - 0.025 14.8 1.5 0.038 14.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 KZN87848.1 - 0.026 14.2 1.0 0.051 13.2 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper FUSC PF04632.7 KZN87848.1 - 0.15 10.4 4.5 0.19 10.0 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc24 PF08286.6 KZN87848.1 - 0.22 11.2 4.9 0.79 9.4 3.4 1.9 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KZN87848.1 - 0.26 10.8 5.1 0.64 9.5 3.5 1.7 1 1 0 1 1 1 0 Septum formation initiator DSL PF01414.14 KZN87849.1 - 0.19 11.7 1.1 0.27 11.2 0.7 1.2 1 0 0 1 1 1 0 Delta serrate ligand Glyco_transf_20 PF00982.16 KZN87850.1 - 3.8e-154 513.6 0.0 4.5e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KZN87850.1 - 6.8e-06 25.6 0.0 0.00013 21.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF4219 PF13961.1 KZN87852.1 - 2.6e-09 36.2 0.5 5.3e-09 35.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KZN87852.1 - 3.7e-07 29.8 0.0 0.0073 15.8 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KZN87852.1 - 8.1e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KZN87852.1 - 0.034 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4645 PF15488.1 KZN87855.1 - 0.16 11.1 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) Tcp11 PF05794.8 KZN87857.1 - 0.07 11.8 7.0 0.11 11.1 4.9 1.3 1 0 0 1 1 1 0 T-complex protein 11 DUF3227 PF11537.3 KZN87857.1 - 0.56 10.3 4.8 2.4 8.3 0.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3227) DUF1054 PF06335.7 KZN87857.1 - 9.8 5.7 13.3 6.2 6.4 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) Zn_clus PF00172.13 KZN87858.1 - 9.8e-08 31.7 10.9 2.1e-07 30.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 KZN87858.1 - 3.1 7.0 8.1 0.37 10.1 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.20 KZN87860.1 - 6.6e-58 195.8 0.1 7.8e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87860.1 - 5.9e-28 97.6 0.0 7.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN87860.1 - 1.2e-05 24.4 0.0 0.0002 20.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like DUF4413 PF14372.1 KZN87861.1 - 6.9e-05 22.7 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 KZN87861.1 - 0.0023 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.11 KZN87864.1 - 2.1e-25 89.1 6.8 2.7e-25 88.8 4.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87864.1 - 1.2e-10 40.6 10.8 3.1e-10 39.2 7.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 KZN87864.1 - 0.02 14.3 2.8 0.81 9.0 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3792 PF12670.2 KZN87864.1 - 5.8 6.8 10.8 0.082 12.7 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) DUF2841 PF11001.3 KZN87866.1 - 1.5e-44 150.9 0.4 2.2e-44 150.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) RhoGEF PF00621.15 KZN87869.1 - 2.3e-33 115.5 0.1 2.8e-32 112.0 0.0 2.5 3 0 0 3 3 3 1 RhoGEF domain BAR PF03114.13 KZN87869.1 - 5.6e-11 42.3 3.3 5.6e-11 42.3 2.3 1.7 2 0 0 2 2 2 1 BAR domain Cyclin PF08613.6 KZN87870.1 - 5.3e-11 43.1 0.0 9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN87870.1 - 3.8e-10 39.4 0.9 6.9e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain RRF_GI PF12614.3 KZN87870.1 - 0.063 13.0 0.6 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 Ribosome recycling factor XLF PF09302.6 KZN87870.1 - 0.12 12.1 1.3 1.2 8.9 0.6 2.1 2 0 0 2 2 2 0 XLF (XRCC4-like factor) IFP_35_N PF07334.8 KZN87870.1 - 2.3 8.2 6.2 4.9 7.2 4.3 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Catalase PF00199.14 KZN87871.1 - 2.6e-58 197.5 1.5 2.6e-31 108.6 0.0 3.1 1 1 2 3 3 3 3 Catalase Catalase-rel PF06628.7 KZN87871.1 - 4.2e-08 32.9 0.1 7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive PP2C PF00481.16 KZN87872.1 - 2.4e-27 95.9 0.6 2.9e-27 95.6 0.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KZN87872.1 - 2.3e-05 24.1 0.1 0.0093 15.6 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KZN87872.1 - 9.4e-05 21.8 0.3 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Caleosin PF05042.8 KZN87874.1 - 1.2e-55 187.7 0.0 1.5e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 KZN87874.1 - 4.2e-05 22.5 4.8 0.00041 19.4 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KZN87874.1 - 5.3e-05 22.7 6.9 0.00017 21.1 0.1 3.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KZN87874.1 - 7.2e-05 22.8 0.1 0.001 19.1 0.1 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KZN87874.1 - 0.0055 16.3 0.3 0.099 12.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KZN87874.1 - 0.015 14.6 10.0 0.017 14.4 0.3 3.6 4 0 0 4 4 4 0 EF hand DUF1959 PF09218.5 KZN87878.1 - 0.065 13.0 0.2 0.4 10.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) Pkinase_Tyr PF07714.12 KZN87879.1 - 0.0067 15.5 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.1 KZN87880.1 - 0.0021 17.8 9.2 0.0034 17.1 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN87880.1 - 0.0027 17.7 10.2 0.0048 16.9 7.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN87880.1 - 0.015 15.4 3.7 0.027 14.5 2.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN87880.1 - 0.036 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) FANCL_C PF11793.3 KZN87880.1 - 1.3 9.0 6.2 2.4 8.1 4.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KZN87880.1 - 1.8 8.6 8.1 3.4 7.7 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN87881.1 - 3.2e-56 187.6 8.8 2.4e-13 50.2 0.0 5.6 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN87881.1 - 6.5e-44 146.9 17.8 4.7e-10 39.3 0.0 9.2 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 KZN87881.1 - 6e-43 142.5 19.3 6.9e-07 28.7 0.0 10.6 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KZN87881.1 - 2.2e-38 129.9 16.6 5.4e-08 33.1 0.0 8.2 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN87881.1 - 9.6e-35 115.1 14.8 0.001 19.1 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat DAP_epimerase PF01678.14 KZN87884.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase GAF_3 PF13492.1 KZN87885.1 - 0.00065 19.7 2.2 15 5.7 0.1 4.8 1 1 1 2 2 2 2 GAF domain CLASP_N PF12348.3 KZN87885.1 - 2.2 7.5 11.4 59 2.9 0.0 6.4 1 1 7 8 8 8 0 CLASP N terminal IncA PF04156.9 KZN87888.1 - 4.4e-05 23.1 1.5 4.4e-05 23.1 1.1 1.4 1 1 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 KZN87888.1 - 8.7e-05 20.4 0.8 0.0001 20.2 0.5 1.1 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 KZN87888.1 - 0.00019 20.0 1.1 0.00026 19.6 0.8 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 KZN87888.1 - 0.00034 20.5 1.4 0.0006 19.6 1.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 KZN87888.1 - 0.00094 19.0 0.9 0.001 18.9 0.6 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 KZN87888.1 - 0.0012 18.8 2.2 0.0022 17.9 1.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1640 PF07798.6 KZN87888.1 - 0.0021 18.1 2.4 0.0051 16.8 1.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF972 PF06156.8 KZN87888.1 - 0.0024 18.2 0.4 0.0041 17.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Laminin_I PF06008.9 KZN87888.1 - 0.011 15.1 2.0 0.016 14.5 1.4 1.2 1 0 0 1 1 1 0 Laminin Domain I ADIP PF11559.3 KZN87888.1 - 0.011 15.6 1.7 0.011 15.6 1.1 1.4 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KZN87888.1 - 0.018 14.2 2.3 0.022 13.9 1.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KZN87888.1 - 0.021 14.3 1.1 0.033 13.7 0.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KZN87888.1 - 0.021 14.6 1.2 0.039 13.8 0.8 1.4 1 0 0 1 1 1 0 Tropomyosin like Filament PF00038.16 KZN87888.1 - 0.024 14.1 1.7 0.051 13.0 1.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein Prominin PF05478.6 KZN87888.1 - 0.024 12.1 0.3 0.029 11.9 0.2 1.1 1 0 0 1 1 1 0 Prominin HALZ PF02183.13 KZN87888.1 - 0.024 14.3 1.3 0.64 9.7 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.4 KZN87888.1 - 0.031 13.2 2.4 0.043 12.7 1.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Imm2 PF14426.1 KZN87888.1 - 0.034 14.1 0.2 0.083 12.9 0.1 1.7 1 1 0 1 1 1 0 Immunity protein Imm2 Herpes_UL6 PF01763.11 KZN87888.1 - 0.035 12.2 0.5 0.047 11.8 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4201 PF13870.1 KZN87888.1 - 0.037 13.4 2.1 0.06 12.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.6 KZN87888.1 - 0.04 12.5 0.9 0.051 12.2 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 KZN87888.1 - 0.048 13.4 0.8 0.12 12.1 0.5 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) GAS PF13851.1 KZN87888.1 - 0.048 12.8 0.8 0.086 12.0 0.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KZN87888.1 - 0.055 12.5 0.4 0.071 12.1 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Apolipoprotein PF01442.13 KZN87888.1 - 0.055 12.9 0.2 0.085 12.3 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2968 PF11180.3 KZN87888.1 - 0.062 12.6 0.3 0.091 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PEP-utilisers_N PF05524.8 KZN87888.1 - 0.076 12.8 0.7 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_MLP1_2 PF07926.7 KZN87888.1 - 0.079 12.7 2.8 0.48 10.1 0.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PMEI PF04043.10 KZN87888.1 - 0.1 12.5 0.3 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Effector_1 PF04518.7 KZN87888.1 - 0.12 11.2 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Effector from type III secretion system FlaC_arch PF05377.6 KZN87888.1 - 0.19 11.6 1.0 6.4 6.7 0.1 2.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 KZN87888.1 - 0.23 11.9 3.3 4.4 7.8 1.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 KZN87888.1 - 0.25 11.6 5.4 0.079 13.2 0.9 2.1 2 1 1 3 3 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KZN87888.1 - 0.6 9.9 4.3 7.6 6.4 0.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KZN87888.1 - 1.7 8.5 7.2 0.25 11.3 2.2 1.7 2 1 0 2 2 1 0 Domain of unknown function (DUF4200) Mto2_bdg PF12808.2 KZN87888.1 - 3.3 7.8 8.3 4.4 7.4 0.1 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3723 PF12520.3 KZN87891.1 - 2.1e-59 201.3 0.2 1.1e-53 182.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF2706 PF10913.3 KZN87892.1 - 0.69 9.5 3.7 0.95 9.1 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2706) BAR_2 PF10455.4 KZN87895.1 - 0.029 13.3 0.1 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Dimer_Tnp_hAT PF05699.9 KZN87897.1 - 2.7e-12 46.1 0.0 1e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Patatin PF01734.17 KZN87898.1 - 5.3e-22 78.7 0.4 1.3e-21 77.5 0.3 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN87898.1 - 0.0016 18.0 5.2 0.0059 16.2 3.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN87898.1 - 0.0019 18.1 8.4 0.0069 16.3 5.8 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN87898.1 - 0.003 17.2 6.8 0.0086 15.7 4.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN87898.1 - 0.12 12.2 8.9 0.38 10.6 6.2 2.0 1 0 0 1 1 1 0 Ring finger domain FxsA PF04186.8 KZN87899.1 - 0.021 14.4 1.9 0.56 9.8 0.0 2.8 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DUF4625 PF15418.1 KZN87901.1 - 0.002 18.2 0.0 0.0056 16.7 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) TACC PF05010.9 KZN87903.1 - 0.0045 16.7 3.9 0.0059 16.3 2.7 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) DUF1604 PF07713.8 KZN87903.1 - 0.088 12.6 0.3 0.29 10.9 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) Aa_trans PF01490.13 KZN87904.1 - 1.3e-74 251.1 27.3 1.5e-74 250.8 18.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Dimer_Tnp_hAT PF05699.9 KZN87905.1 - 1.8e-12 46.7 0.0 1.1e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KZN87905.1 - 1e-07 31.8 0.0 3.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-RING_2 PF13639.1 KZN87906.1 - 0.0012 18.5 7.9 0.0021 17.8 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN87906.1 - 0.0017 18.3 8.4 0.0034 17.3 5.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN87906.1 - 0.018 15.1 2.6 0.038 14.0 1.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN87906.1 - 0.054 13.3 0.1 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN87906.1 - 1.8 8.6 6.9 3.7 7.6 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.12 KZN87907.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3435 PF11917.3 KZN87909.1 - 1.9e-161 537.4 0.4 4.3e-161 536.3 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KZN87909.1 - 1.2 9.6 3.5 1.2 9.6 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type XFP_N PF09364.5 KZN87911.1 - 1e-179 597.0 0.0 1.3e-179 596.6 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KZN87911.1 - 1.4e-87 292.3 0.0 2.1e-87 291.7 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KZN87911.1 - 5e-83 277.0 0.0 9.3e-83 276.1 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Methyltransf_11 PF08241.7 KZN87912.1 - 1.1e-17 64.3 0.0 2.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN87912.1 - 3.4e-15 56.1 0.0 4.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN87912.1 - 4.3e-14 53.0 0.0 6.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN87912.1 - 8.8e-14 51.6 0.0 2.1e-13 50.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN87912.1 - 6.4e-13 49.0 0.0 1.4e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN87912.1 - 9.2e-12 44.8 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN87912.1 - 2.1e-09 37.4 0.0 3.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN87912.1 - 2.1e-08 33.5 0.0 2.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KZN87912.1 - 5.4e-07 29.1 0.0 9.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 KZN87912.1 - 1.3e-05 24.5 0.1 0.13 11.5 0.0 2.6 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain CMAS PF02353.15 KZN87912.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KZN87912.1 - 0.0018 17.7 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KZN87912.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase N2227 PF07942.7 KZN87912.1 - 0.011 14.7 0.0 0.26 10.2 0.0 2.2 1 1 1 2 2 2 0 N2227-like protein TehB PF03848.9 KZN87912.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB AviRa PF11599.3 KZN87912.1 - 0.031 13.3 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa RrnaAD PF00398.15 KZN87912.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Nse4_C PF08743.5 KZN87913.1 - 8.2e-34 115.4 0.0 2.4e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KZN87913.1 - 1.5e-17 63.1 0.8 4.9e-17 61.5 0.2 2.3 2 1 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.15 KZN87914.1 - 4.7e-58 195.4 0.4 7.9e-58 194.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KZN87914.1 - 2e-41 142.0 0.0 3.1e-39 134.8 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KZN87914.1 - 2.2e-25 89.1 0.0 3.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 KZN87914.1 - 0.023 14.5 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 C2 domain Grp1_Fun34_YaaH PF01184.14 KZN87915.1 - 4.8e-67 225.3 14.2 6.1e-67 224.9 9.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 KZN87915.1 - 2 7.3 4.4 2.7 6.9 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_32N PF00251.15 KZN87917.1 - 2.8e-52 177.9 0.2 5.6e-35 121.1 0.4 3.1 1 1 2 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN87917.1 - 3e-18 65.9 0.1 1.6e-17 63.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Zn_clus PF00172.13 KZN87918.1 - 1.8e-09 37.3 10.7 4.5e-09 36.0 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KZN87919.1 - 9.5e-58 195.3 10.5 9.5e-58 195.3 7.3 1.3 2 0 0 2 2 2 1 RTA1 like protein Endonuc_BglI PF14562.1 KZN87919.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI MMR_HSR1 PF01926.18 KZN87922.1 - 1.8e-14 53.7 0.1 4.3e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KZN87922.1 - 9.5e-07 28.1 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KZN87922.1 - 2.9e-06 26.6 0.1 4.3e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KZN87922.1 - 4.6e-05 22.6 0.0 7.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KZN87922.1 - 0.0019 17.3 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 KZN87922.1 - 0.0021 17.5 0.0 0.008 15.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KZN87922.1 - 0.009 16.4 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 KZN87922.1 - 0.0097 15.6 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KZN87922.1 - 0.016 15.5 0.1 0.045 14.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN87922.1 - 0.022 15.5 0.1 0.079 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 KZN87922.1 - 0.029 13.5 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.16 KZN87922.1 - 0.032 13.4 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 KZN87922.1 - 0.033 14.0 0.1 0.39 10.5 0.0 2.3 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.15 KZN87922.1 - 0.04 12.5 0.1 0.057 12.1 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 KZN87922.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KZN87922.1 - 0.15 11.5 0.1 8.7 5.8 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Isy1 PF06246.7 KZN87923.1 - 7.3e-84 281.1 0.7 8.9e-84 280.8 0.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Myosin_head PF00063.16 KZN87924.1 - 1.1e-246 820.1 0.0 4.4e-246 818.2 0.0 2.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KZN87924.1 - 7.9e-34 116.5 281.1 1.8e-21 75.6 90.3 5.9 1 1 3 4 4 4 4 Myosin tail Myosin_N PF02736.14 KZN87924.1 - 0.0044 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KZN87924.1 - 0.07 12.8 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 KZN87925.1 - 3.4e-13 48.8 0.5 5.1e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Mem_trans PF03547.13 KZN87925.1 - 4.4 5.4 5.3 3.1 6.0 0.3 2.2 2 0 0 2 2 2 0 Membrane transport protein zf-DHHC PF01529.15 KZN87926.1 - 5.8e-26 90.9 10.8 2e-25 89.1 6.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_hydro_17 PF00332.13 KZN87929.1 - 2.8e-07 29.8 4.3 0.00013 21.1 0.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Gly-zipper_Omp PF13488.1 KZN87929.1 - 2.7 7.6 22.0 0.071 12.7 1.9 3.0 3 0 0 3 3 3 0 Glycine zipper SRR1 PF07985.7 KZN87930.1 - 2.7e-14 52.7 0.0 5.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KZN87930.1 - 0.023 14.7 0.4 0.056 13.4 0.1 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF1688 PF07958.6 KZN87930.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Abhydrolase_6 PF12697.2 KZN87934.1 - 1.4e-23 84.0 5.9 4.6e-23 82.2 4.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN87934.1 - 2.9e-09 36.8 0.3 1.4e-08 34.6 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN87934.1 - 7.7e-09 35.4 0.2 1.8e-08 34.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN87934.1 - 4e-08 33.0 0.0 1.5e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KZN87934.1 - 0.0011 18.4 0.2 0.0045 16.4 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 KZN87934.1 - 0.045 12.9 2.0 0.079 12.1 0.9 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase Peptidase_M28 PF04389.12 KZN87935.1 - 1.4e-32 112.9 0.1 2.4e-32 112.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KZN87935.1 - 4.9e-12 45.4 1.2 1.3e-11 44.0 0.5 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 KZN87935.1 - 0.0051 15.6 0.0 0.03 13.1 0.0 2.1 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KZN87936.1 - 2.3e-11 43.0 8.0 2.3e-11 43.0 5.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 KZN87937.1 - 1.6e-08 34.3 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN87937.1 - 5.8e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Amidase PF01425.16 KZN87938.1 - 6.7e-92 308.6 0.0 9e-92 308.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 KZN87939.1 - 2.9e-19 68.9 0.9 5.9e-19 67.9 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN87939.1 - 1.4e-08 34.5 9.2 2.7e-08 33.5 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KZN87940.1 - 3.2e-22 78.9 0.0 4.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN87940.1 - 0.00022 20.3 0.0 0.0012 18.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Transferase PF02458.10 KZN87941.1 - 1.7e-09 36.6 0.0 1.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family HsbA PF12296.3 KZN87942.1 - 1.9e-17 63.3 0.0 2.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Acyl_transf_1 PF00698.16 KZN87943.1 - 5.4e-72 242.8 0.0 8e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KZN87943.1 - 4.5e-67 226.2 0.0 9e-67 225.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KZN87943.1 - 2.7e-58 197.4 0.0 4.9e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KZN87943.1 - 5.7e-54 182.6 0.0 9.5e-54 181.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 KZN87943.1 - 2.8e-35 121.6 0.0 2.4e-34 118.5 0.0 2.5 2 1 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 KZN87943.1 - 1.2e-31 109.0 0.3 2.6e-31 107.9 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KZN87943.1 - 6.8e-25 87.9 0.1 1.8e-23 83.2 0.0 3.1 3 0 0 3 3 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 KZN87943.1 - 1.8e-20 73.2 0.0 7.7e-20 71.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KZN87943.1 - 2e-17 62.9 0.1 5.6e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KZN87943.1 - 1.7e-13 50.4 0.0 5.3e-13 48.8 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN87943.1 - 2.9e-12 46.6 0.0 1.2e-11 44.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN87943.1 - 1.2e-11 45.6 0.0 4.9e-11 43.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KZN87943.1 - 8.5e-10 39.2 0.0 3.9e-09 37.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KZN87943.1 - 5.8e-09 35.7 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KZN87943.1 - 6.8e-09 36.1 0.0 3.6e-08 33.7 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KZN87943.1 - 8.7e-08 31.9 0.4 3.4e-07 29.9 0.2 2.2 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 KZN87943.1 - 3.1e-06 26.1 0.0 9.8e-06 24.4 0.0 1.9 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KZN87943.1 - 6.9e-05 22.3 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF938 PF06080.7 KZN87943.1 - 0.004 16.7 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KZN87943.1 - 0.0073 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KZN87943.1 - 0.017 14.1 0.4 0.036 13.0 0.3 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KZN87943.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain MTS PF05175.9 KZN87943.1 - 0.037 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 KZN87943.1 - 0.06 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KZN87943.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase ACP_syn_III PF08545.5 KZN87943.1 - 0.078 12.6 2.6 0.056 13.1 0.2 2.0 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 KZN87943.1 - 0.12 12.6 0.1 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site RrnaAD PF00398.15 KZN87943.1 - 0.2 10.6 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase eIF-5a PF01287.15 KZN87944.1 - 0.0032 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold MAPEG PF01124.13 KZN87945.1 - 1.4e-08 34.4 2.1 2e-08 33.8 1.4 1.2 1 0 0 1 1 1 1 MAPEG family PHD PF00628.24 KZN87946.1 - 3.3e-09 36.2 2.0 8.1e-09 35.0 1.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KZN87946.1 - 0.06 12.6 1.9 0.098 11.9 1.3 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 KZN87946.1 - 2.4 7.9 4.8 2 8.1 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MARVEL PF01284.18 KZN87948.1 - 2.3e-09 37.1 1.7 2.3e-09 37.1 1.2 2.0 2 0 0 2 2 2 1 Membrane-associating domain VIT1 PF01988.14 KZN87948.1 - 0.001 18.6 0.2 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 VIT family DIOX_N PF14226.1 KZN87950.1 - 1.4e-09 38.4 0.0 2.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short_C2 PF13561.1 KZN87951.1 - 1.6e-26 93.5 0.0 2e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN87951.1 - 8.9e-21 74.5 0.5 1.2e-20 74.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN87951.1 - 2.4e-11 43.6 0.2 3.5e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 KR domain CPSase_L_D2 PF02786.12 KZN87952.1 - 1.8e-73 246.3 0.0 3.6e-73 245.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KZN87952.1 - 5.4e-37 126.0 0.0 1.3e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KZN87952.1 - 1e-33 115.7 0.0 2.1e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KZN87952.1 - 1.2e-18 67.5 0.0 3e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KZN87952.1 - 4.5e-18 64.6 0.4 1.5e-17 62.9 0.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KZN87952.1 - 6.7e-13 48.0 0.0 1.5e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KZN87952.1 - 9e-10 38.2 0.0 2.1e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KZN87952.1 - 3e-07 29.9 0.0 6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KZN87952.1 - 2e-06 27.3 0.0 0.0023 17.5 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KZN87952.1 - 1.6e-05 24.8 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KZN87952.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 KZN87952.1 - 0.0021 18.3 0.0 4.3 7.7 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATPgrasp_ST PF14397.1 KZN87952.1 - 0.017 14.1 0.0 0.045 12.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 KZN87952.1 - 0.019 14.4 0.0 0.25 10.7 0.0 2.4 3 0 0 3 3 3 0 RimK-like ATP-grasp domain GCV_H PF01597.14 KZN87952.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF3415 PF11895.3 KZN87953.1 - 0.064 13.1 0.3 4.4 7.2 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3415) Acyl-CoA_dh_1 PF00441.19 KZN87955.1 - 2.5e-40 138.0 1.3 4e-40 137.3 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN87955.1 - 4.6e-33 114.1 0.1 9.4e-33 113.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KZN87955.1 - 1.5e-20 72.4 0.3 4e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN87955.1 - 6.5e-16 58.7 0.3 1.1e-15 58.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KZN87955.1 - 0.0021 17.4 0.1 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 KZN87956.1 - 6.5e-142 473.3 0.1 7.9e-142 473.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Kdo PF06293.9 KZN87957.1 - 0.0011 18.0 0.1 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN87957.1 - 0.0013 18.5 0.5 0.0086 15.8 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN87957.1 - 0.0038 16.5 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KZN87957.1 - 0.068 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF1649 PF07855.7 KZN87958.1 - 1.8e-63 213.0 0.0 2e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Peroxin-3 PF04882.7 KZN87959.1 - 4.1e-150 500.2 0.0 5e-150 499.9 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 CAF1A PF12253.3 KZN87961.1 - 1.1e-23 83.1 6.1 1.1e-23 83.1 4.2 4.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KZN87961.1 - 2.3e-10 40.2 82.4 6.1e-10 38.8 57.0 1.9 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KZN87961.1 - 8.2e-06 24.5 47.6 1.3e-05 23.9 33.0 1.5 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 KZN87961.1 - 1.5 7.0 3.6 2.3 6.3 2.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF912 PF06024.7 KZN87961.1 - 2.3 8.3 0.0 2.3 8.3 0.0 3.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mitofilin PF09731.4 KZN87961.1 - 8.8 4.8 36.5 13 4.2 25.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IPP-2 PF04979.9 KZN87963.1 - 1.6e-08 34.8 18.0 1.6e-06 28.4 2.1 2.6 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.3 KZN87963.1 - 0.032 13.8 0.3 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) MFS_1 PF07690.11 KZN87964.1 - 1.1e-32 113.1 28.9 5.9e-28 97.5 17.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN87964.1 - 2.2e-05 23.0 23.4 0.0066 14.9 6.0 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_3 PF05977.8 KZN87964.1 - 0.00047 18.3 4.9 0.00047 18.3 3.4 2.9 3 0 0 3 3 3 1 Transmembrane secretion effector LacY_symp PF01306.14 KZN87964.1 - 0.0011 17.5 16.5 0.19 10.2 3.1 3.3 3 0 0 3 3 3 3 LacY proton/sugar symporter MFS_1_like PF12832.2 KZN87964.1 - 0.0032 17.2 4.9 0.017 14.9 0.1 3.1 3 0 0 3 3 3 1 MFS_1 like family ATG22 PF11700.3 KZN87964.1 - 1.1 7.7 20.8 0.072 11.5 3.0 2.8 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like Aldo_ket_red PF00248.16 KZN87965.1 - 1.1e-53 181.9 0.0 1.3e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CRAL_TRIO PF00650.15 KZN87966.1 - 2.1e-15 56.5 0.0 3.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN87966.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 KZN87966.1 - 0.011 15.3 0.0 0.059 13.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Ubiquitin DUF1546 PF07571.8 KZN87967.1 - 8.8e-35 118.7 0.0 2.1e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KZN87967.1 - 7.8e-24 83.4 0.0 2.9e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KZN87967.1 - 1e-07 31.9 0.4 3.3e-07 30.3 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN87967.1 - 0.044 13.8 0.8 0.11 12.6 0.1 2.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_decarbox PF01536.11 KZN87968.1 - 1.2e-86 290.3 0.0 1.1e-85 287.2 0.0 2.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.9 KZN87969.1 - 3.6e-19 68.3 0.0 7.6e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region KTI12 PF08433.5 KZN87969.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2849 PF11011.3 KZN87969.1 - 2 8.7 8.6 2 8.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) DUF605 PF04652.11 KZN87969.1 - 2.7 7.2 14.4 0.018 14.4 3.9 1.8 2 0 0 2 2 2 0 Vta1 like Acyl_transf_3 PF01757.17 KZN87970.1 - 9.2e-20 70.7 26.1 2.8e-19 69.1 18.1 1.8 1 1 0 1 1 1 1 Acyltransferase family 60KD_IMP PF02096.15 KZN87971.1 - 1.5e-39 135.7 0.9 1.5e-39 135.7 0.6 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein TOM13 PF08219.6 KZN87972.1 - 1.1e-31 108.3 0.1 1.5e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 MFS_1 PF07690.11 KZN87973.1 - 1.3e-40 139.2 29.0 1.3e-40 139.2 20.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN87973.1 - 6.9e-09 34.7 26.8 2.2e-08 33.1 18.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KZN87973.1 - 1.2e-07 30.3 2.1 2.2e-07 29.4 1.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 KZN87973.1 - 0.0011 18.7 0.6 0.0011 18.7 0.4 2.6 3 0 0 3 3 3 1 Predicted membrane protein (DUF2178) DUF3169 PF11368.3 KZN87973.1 - 0.004 16.3 0.1 0.97 8.5 0.0 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF3169) FAD_binding_3 PF01494.14 KZN87974.1 - 3.5e-25 88.8 0.0 1.7e-24 86.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN87974.1 - 1.1e-09 37.6 0.2 1.1e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN87974.1 - 8.5e-05 22.5 0.3 0.0002 21.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN87974.1 - 0.00016 20.7 3.4 0.12 11.2 0.3 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KZN87974.1 - 0.00021 20.2 0.5 0.00035 19.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KZN87974.1 - 0.00042 19.5 1.1 0.29 10.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KZN87974.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN87974.1 - 0.0084 15.2 0.3 0.015 14.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KZN87974.1 - 0.011 14.4 0.0 0.032 12.8 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KZN87974.1 - 0.045 13.7 2.4 0.28 11.2 1.7 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN87974.1 - 0.068 11.6 2.0 0.23 9.8 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 KZN87974.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KZN87974.1 - 0.16 10.8 2.3 0.59 8.9 1.6 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KZN87974.1 - 0.23 11.8 7.3 0.064 13.6 0.8 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.16 KZN87975.1 - 0.00067 19.5 1.9 0.0011 18.8 1.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor PLDc_2 PF13091.1 KZN87976.1 - 1.5e-13 50.5 0.0 2.5e-05 23.9 0.0 3.5 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 KZN87976.1 - 1.4e-12 46.9 1.9 3.3e-05 23.5 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_transf_20 PF00982.16 KZN87977.1 - 1.1e-157 525.2 0.0 1.3e-157 525.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KZN87977.1 - 9.4e-06 25.1 0.1 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Hemerythrin PF01814.18 KZN87978.1 - 9.1e-17 61.4 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GPCR_chapero_1 PF11904.3 KZN87978.1 - 0.012 14.8 0.6 0.014 14.6 0.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone NAAA-beta PF15508.1 KZN87978.1 - 0.069 13.5 0.1 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ADH_N PF08240.7 KZN87979.1 - 9.2e-29 99.3 1.8 1.1e-28 99.1 0.3 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN87979.1 - 3.8e-22 78.2 0.2 7.3e-22 77.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KZN87979.1 - 0.0049 16.9 0.1 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KZN87979.1 - 0.0068 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KZN87979.1 - 0.0091 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 KZN87979.1 - 0.021 14.8 0.1 0.063 13.2 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.14 KZN87979.1 - 0.023 13.7 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KZN87979.1 - 0.11 12.9 0.6 0.4 11.1 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Kinetochor_Ybp2 PF08568.5 KZN87980.1 - 1e-151 506.3 0.1 1.2e-151 506.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.17 KZN87981.1 - 3e-33 114.9 8.5 3e-33 114.9 5.9 1.8 2 0 0 2 2 2 1 Rhomboid family DUF4203 PF13886.1 KZN87981.1 - 0.014 14.8 0.3 0.014 14.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) GRP PF07172.6 KZN87982.1 - 0.0059 17.0 5.7 0.0062 16.9 4.0 1.2 1 0 0 1 1 1 1 Glycine rich protein family API5 PF05918.6 KZN87982.1 - 0.93 7.9 3.6 0.95 7.8 2.5 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-DHHC PF01529.15 KZN87983.1 - 2e-42 144.5 1.9 2e-42 144.5 1.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase UQ_con PF00179.21 KZN87984.1 - 5.8e-21 74.4 0.0 8.1e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN87984.1 - 0.061 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain B-block_TFIIIC PF04182.7 KZN87985.1 - 3.5e-19 68.4 0.0 7.7e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TRAP-gamma PF07074.7 KZN87986.1 - 0.057 12.9 1.0 0.12 11.9 0.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3329 PF11808.3 KZN87986.1 - 2.7 8.1 6.7 0.18 11.9 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3329) Fmp27 PF10344.4 KZN87987.1 - 2e-241 803.3 0.0 2e-241 803.3 0.0 2.3 4 0 0 4 4 4 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KZN87987.1 - 4.6e-166 553.2 0.0 4.6e-166 553.2 0.0 3.9 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KZN87987.1 - 3.2e-154 513.8 1.9 3.2e-154 513.8 1.3 2.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KZN87987.1 - 1.9e-54 183.6 0.1 4.4e-54 182.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KZN87987.1 - 1.2e-52 177.9 0.0 3.6e-52 176.4 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KZN87987.1 - 1.3e-29 102.6 0.1 6.7e-29 100.3 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Osmo_CC PF08946.5 KZN87988.1 - 0.045 13.7 1.2 0.073 13.1 0.8 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Gly-zipper_OmpA PF13436.1 KZN87988.1 - 0.12 12.0 0.4 16 5.1 0.1 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain RRM_1 PF00076.17 KZN87989.1 - 2.1e-16 59.2 0.0 2.1e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN87989.1 - 9.9e-15 54.2 0.0 1.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN87989.1 - 7.3e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec2p PF06428.6 KZN87990.1 - 2.3e-09 37.0 12.5 2.3e-09 37.0 8.6 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Spc7 PF08317.6 KZN87990.1 - 0.029 13.0 6.1 0.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.4 KZN87990.1 - 0.11 12.4 11.9 11 6.0 0.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 KZN87990.1 - 0.14 12.1 0.2 0.14 12.1 0.1 3.2 2 1 1 3 3 3 0 bZIP transcription factor ECSIT PF06239.6 KZN87990.1 - 0.21 10.4 2.2 0.35 9.6 1.5 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Fib_alpha PF08702.5 KZN87990.1 - 0.3 11.1 2.8 9.8 6.2 1.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KZN87990.1 - 0.33 11.3 6.5 8.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AATF-Che1 PF13339.1 KZN87990.1 - 0.55 10.3 7.4 2.8 8.0 3.1 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Atg14 PF10186.4 KZN87990.1 - 1.6 7.6 12.6 7.3 5.4 0.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HR1 PF02185.11 KZN87990.1 - 1.7 8.4 13.6 5.3 6.8 5.1 3.0 2 2 0 2 2 2 0 Hr1 repeat COG2 PF06148.6 KZN87990.1 - 2.8 7.8 10.5 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KZN87990.1 - 4.5 6.8 22.1 12 5.4 0.1 2.3 2 1 0 2 2 2 0 IncA protein Striatin PF08232.7 KZN87990.1 - 7.4 6.8 15.5 0.085 13.1 0.5 2.7 2 1 0 2 2 2 0 Striatin family ATG16 PF08614.6 KZN87990.1 - 9.3 6.0 20.8 2e+03 -1.6 13.5 2.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2630 PF10944.3 KZN87990.1 - 9.3 6.4 17.1 0.68 10.0 3.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2630) Ribosomal_L32e PF01655.13 KZN87991.1 - 1.1e-48 163.7 1.3 2.3e-48 162.8 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 GFO_IDH_MocA PF01408.17 KZN87991.1 - 5.1e-19 68.9 0.0 1.1e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN87991.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Fringe PF02434.11 KZN87992.1 - 7.6e-06 25.3 3.9 5.2e-05 22.5 0.1 3.1 3 1 0 3 3 3 1 Fringe-like PAN_4 PF14295.1 KZN87992.1 - 0.1 12.2 2.9 0.21 11.2 1.0 2.1 2 0 0 2 2 2 0 PAN domain PAN_3 PF08277.7 KZN87992.1 - 0.14 11.7 0.6 0.34 10.5 0.4 1.6 1 0 0 1 1 1 0 PAN-like domain PseudoU_synth_2 PF00849.17 KZN87993.1 - 3.2e-25 88.8 0.0 5e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KZN87993.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain Glyco_tran_WecB PF03808.8 KZN87993.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family GFA PF04828.9 KZN87993.1 - 0.18 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme GATA PF00320.22 KZN87995.1 - 0.11 11.8 15.6 0.24 10.7 0.3 3.8 4 0 0 4 4 4 0 GATA zinc finger DUF3795 PF12675.2 KZN87995.1 - 5.7 7.1 13.7 4.3 7.5 3.2 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3795) Rpr2 PF04032.11 KZN87995.1 - 5.8 6.8 10.6 0.34 10.8 1.8 2.6 2 2 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TBX PF12598.3 KZN87996.1 - 3.8 7.9 9.6 0.48 10.8 1.2 2.5 2 0 0 2 2 2 0 T-box transcription factor Aegerolysin PF06355.8 KZN87997.1 - 7.7e-26 90.5 0.2 9.1e-26 90.2 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin NAD_binding_10 PF13460.1 KZN87998.1 - 0.004 17.1 0.8 0.01 15.8 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN87998.1 - 0.0078 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KZN87998.1 - 0.018 13.7 0.1 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN87998.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hexapep PF00132.19 KZN87999.1 - 1.5e-09 36.9 9.5 3.2e-05 23.2 1.5 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 KZN87999.1 - 0.0011 17.6 3.4 0.11 11.0 0.4 2.3 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 KZN87999.1 - 1.6 8.3 17.1 7.7 6.1 0.3 4.0 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase 4HBT PF03061.17 KZN88000.1 - 5.1e-14 52.1 0.0 8.5e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KZN88000.1 - 6e-07 29.9 0.0 8.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KZN88000.1 - 0.0012 17.8 0.2 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DCP2 PF05026.8 KZN88000.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Dcp2, box A domain MFS_1 PF07690.11 KZN88003.1 - 3.9e-27 94.9 67.7 5.9e-22 77.8 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tenui_NS4 PF03300.8 KZN88003.1 - 0.81 8.7 2.2 1.9 7.5 0.1 2.0 2 0 0 2 2 2 0 Tenuivirus non-structural protein NS4 ADH_zinc_N PF00107.21 KZN88004.1 - 0.00033 20.1 0.0 0.00088 18.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN88004.1 - 0.00052 19.7 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 KZN88005.1 - 4.1e-174 578.8 0.0 9.9e-100 333.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KZN88005.1 - 7.4e-46 156.3 0.3 4e-27 94.8 0.1 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KZN88005.1 - 4.8e-19 68.3 0.7 1.8e-09 37.6 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN88005.1 - 2.8e-18 66.6 0.2 2e-11 44.6 0.0 3.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF2802 PF10975.3 KZN88005.1 - 0.2 11.4 0.1 0.96 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Aa_trans PF01490.13 KZN88006.1 - 2.5e-30 105.2 25.0 3.5e-30 104.8 17.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.19 KZN88007.1 - 2.3e-116 389.0 29.9 2.6e-116 388.8 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88007.1 - 9.7e-23 80.4 62.8 1.6e-20 73.1 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF204 PF02659.10 KZN88007.1 - 0.29 11.3 0.1 0.29 11.3 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function DUF CTDII PF01556.13 KZN88008.1 - 4.9e-23 80.8 0.2 1.4e-20 72.9 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KZN88008.1 - 7.4e-16 57.6 4.2 2.9e-15 55.7 2.9 2.0 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KZN88008.1 - 1.3e-13 50.7 20.7 2.2e-13 50.0 14.3 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CHY PF05495.7 KZN88008.1 - 0.37 10.9 10.8 1.9 8.7 1.3 2.4 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.14 KZN88008.1 - 0.76 9.4 11.5 2.1 8.0 1.5 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family tRNA-synt_1c PF00749.16 KZN88009.1 - 2.6e-96 322.0 0.0 3.2e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MAP65_ASE1 PF03999.7 KZN88010.1 - 9.4e-75 252.4 0.1 1.7e-74 251.5 0.1 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.6 KZN88010.1 - 0.03 11.8 0.5 0.048 11.2 0.4 1.2 1 0 0 1 1 1 0 Prominin AIPR PF10592.4 KZN88010.1 - 0.2 10.9 0.1 0.42 9.8 0.1 1.4 1 0 0 1 1 1 0 AIPR protein PEP-utilisers_N PF05524.8 KZN88010.1 - 0.32 10.7 6.0 2.8 7.7 0.3 3.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal LTXXQ PF07813.7 KZN88010.1 - 0.45 10.9 6.9 2.9 8.4 0.2 3.7 3 0 0 3 3 3 0 LTXXQ motif family protein DUF4530 PF15039.1 KZN88010.1 - 2.4 8.0 7.6 7.6 6.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4530) LXG PF04740.7 KZN88010.1 - 2.5 7.8 6.3 1.8 8.3 0.3 3.3 4 0 0 4 4 4 0 LXG domain of WXG superfamily Spectrin PF00435.16 KZN88010.1 - 8.9 6.6 14.4 1.1 9.6 0.6 4.2 3 2 1 4 4 4 0 Spectrin repeat JAB PF01398.16 KZN88011.1 - 1.3e-28 98.9 0.1 2.8e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KZN88011.1 - 1.9e-07 30.6 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RasGEF PF00617.14 KZN88012.1 - 8.8e-64 214.7 0.0 1.5e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KZN88012.1 - 2.6e-29 101.3 0.7 5.9e-29 100.2 0.5 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KZN88012.1 - 6.3e-15 54.2 0.2 6.3e-15 54.2 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KZN88012.1 - 1.7e-13 49.9 0.2 5.1e-13 48.3 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KZN88012.1 - 1.4e-10 40.4 0.2 4.9e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 KZN88012.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.13 KZN88013.1 - 4.5e-19 68.3 1.7 6.8e-19 67.7 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KZN88013.1 - 4.6e-07 29.8 15.2 9.8e-05 22.4 4.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN88013.1 - 5.5e-05 23.2 13.3 0.0039 17.4 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN88013.1 - 0.00019 21.5 14.4 0.033 14.5 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN88013.1 - 0.56 10.1 4.2 15 5.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger UPRTase PF14681.1 KZN88014.1 - 3.6e-75 251.7 0.0 4.2e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KZN88014.1 - 1.7e-06 27.7 0.1 5.4e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.10 KZN88015.1 - 2.7e-28 98.1 28.8 8.4e-19 67.5 4.8 3.9 3 1 0 3 3 3 2 CrcB-like protein MHYT PF03707.11 KZN88016.1 - 0.045 13.8 0.1 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Tad PF13400.1 KZN88016.1 - 1 9.4 4.3 0.33 11.0 0.7 1.8 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DZR PF12773.2 KZN88018.1 - 6.4 6.6 37.8 6.5 6.6 0.2 6.4 3 2 2 5 5 5 0 Double zinc ribbon RNA_pol_Rpc4 PF05132.9 KZN88019.1 - 7.9e-33 113.2 0.0 7.9e-33 113.2 0.0 3.6 3 2 1 4 4 4 1 RNA polymerase III RPC4 Zn_clus PF00172.13 KZN88020.1 - 0.0022 17.8 12.5 0.0041 16.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KZN88020.1 - 0.048 12.9 0.0 0.16 11.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.18 KZN88022.1 - 1.5e-41 140.9 0.1 3.4e-41 139.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KZN88022.1 - 2.9e-30 104.6 0.0 6.9e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF433 PF04255.9 KZN88022.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HA2 PF04408.18 KZN88023.1 - 9e-20 70.6 0.3 2.5e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KZN88023.1 - 1.8e-18 66.3 0.0 3.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 KZN88023.1 - 1.2e-14 54.1 0.1 2.4e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.26 KZN88023.1 - 9.1e-13 47.8 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN88023.1 - 1.3e-09 37.7 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN88023.1 - 0.00024 21.2 0.9 0.0017 18.4 0.6 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KZN88023.1 - 0.0022 16.9 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KZN88023.1 - 0.0046 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DND1_DSRM PF14709.1 KZN88023.1 - 0.0051 17.0 0.1 0.015 15.5 0.1 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PhoH PF02562.11 KZN88023.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 KZN88023.1 - 0.028 14.7 0.1 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KZN88023.1 - 0.031 13.3 0.1 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 KZN88023.1 - 0.036 13.8 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 KZN88023.1 - 0.059 12.8 0.0 0.25 10.8 0.0 2.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 KZN88023.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DcpS_C PF11969.3 KZN88024.1 - 2.7e-18 66.2 3.3 2.1e-17 63.4 2.3 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KZN88024.1 - 6.2e-17 61.9 0.5 1.4e-16 60.7 0.3 1.6 1 1 0 1 1 1 1 HIT domain TRAP_alpha PF03896.11 KZN88025.1 - 3.6e-13 49.1 0.1 7.9e-13 48.0 0.1 1.6 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit FAP PF07174.6 KZN88026.1 - 0.21 10.8 8.9 0.35 10.1 6.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) POT1 PF02765.12 KZN88027.1 - 3.7e-14 52.8 0.0 6.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 KZN88027.1 - 0.0013 18.4 0.0 0.046 13.5 0.0 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Arm PF00514.18 KZN88028.1 - 2.1e-90 293.8 11.5 3.6e-14 51.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 KZN88028.1 - 2.7e-22 78.7 5.1 4.7e-22 77.9 3.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 KZN88028.1 - 2.8e-22 78.7 0.3 5.5e-09 36.1 0.0 5.5 1 1 5 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KZN88028.1 - 3e-19 68.9 8.9 2.4e-09 37.4 0.0 6.1 6 1 1 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KZN88028.1 - 5.1e-18 63.4 0.1 1.1e-06 28.1 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 KZN88028.1 - 3.1e-11 42.8 0.0 0.00069 18.8 0.0 4.2 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.3 KZN88028.1 - 0.00015 21.6 0.0 1.2 9.0 0.0 4.6 4 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KZN88028.1 - 0.014 13.7 0.0 1.2 7.3 0.0 2.8 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KZN88028.1 - 0.022 15.1 1.2 1.2 9.8 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat STAG PF08514.6 KZN88029.1 - 1.7e-37 127.6 0.5 5.8e-37 125.9 0.3 1.9 1 0 0 1 1 1 1 STAG domain Nipped-B_C PF12830.2 KZN88029.1 - 0.0076 15.9 0.0 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cnd1 PF12717.2 KZN88029.1 - 0.012 15.5 0.2 0.22 11.3 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MIF4G PF02854.14 KZN88029.1 - 0.02 14.3 0.1 0.3 10.4 0.0 2.7 3 0 0 3 3 3 0 MIF4G domain FlgM PF04316.8 KZN88029.1 - 0.32 10.9 5.7 0.29 11.1 2.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM UreD PF01774.12 KZN88030.1 - 5.5e-57 192.6 0.0 3.9e-56 189.8 0.0 1.9 1 1 0 1 1 1 1 UreD urease accessory protein S1 PF00575.18 KZN88032.1 - 8.2e-83 272.5 26.8 3.4e-17 62.2 0.6 12.8 13 0 0 13 13 13 10 S1 RNA binding domain TPR_16 PF13432.1 KZN88032.1 - 5.6e-08 33.2 0.6 0.24 12.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88032.1 - 6.2e-08 32.8 0.0 0.03 14.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88032.1 - 1.1e-05 25.6 6.4 0.74 10.6 0.7 5.5 2 1 5 7 7 6 2 Tetratricopeptide repeat Suf PF05843.9 KZN88032.1 - 7.6e-05 22.5 0.1 0.0025 17.5 0.0 5.0 3 2 2 5 5 4 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 KZN88032.1 - 0.00026 20.7 0.3 0.00047 19.9 0.2 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 SDA1 PF05285.7 KZN88032.1 - 0.0012 18.2 20.1 0.0012 18.2 13.9 3.0 3 1 0 3 3 2 1 SDA1 TPR_15 PF13429.1 KZN88032.1 - 0.0014 17.7 2.0 0.29 10.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN88032.1 - 0.012 15.2 0.3 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 TPR repeat PPR PF01535.15 KZN88032.1 - 0.025 14.5 0.2 12 6.1 0.0 3.6 3 0 0 3 3 3 0 PPR repeat TPR_12 PF13424.1 KZN88032.1 - 0.029 14.3 1.8 1.2 9.0 0.2 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.27 KZN88033.1 - 4.8e-26 89.6 4.5 6.7e-07 28.9 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 KZN88033.1 - 0.083 11.0 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Cpn60_TCP1 PF00118.19 KZN88035.1 - 7.2e-142 473.4 15.4 8.2e-142 473.2 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 KZN88036.1 - 4.2e-21 75.2 0.0 6.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 KZN88036.1 - 5.8e-21 74.1 1.9 1.6e-20 72.7 1.3 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 KZN88036.1 - 5.9e-10 38.9 0.0 2.6e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain MecA_N PF05223.6 KZN88036.1 - 0.99 9.4 5.7 48 4.0 0.0 2.8 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain RNase_PH PF01138.16 KZN88038.1 - 1.3e-30 106.4 0.0 2.6e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 KZN88039.1 - 1.3e-56 189.2 14.6 2.2e-36 124.1 0.5 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase Kinesin PF00225.18 KZN88040.1 - 5.5e-59 199.5 0.5 7.3e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain ANAPC15 PF15243.1 KZN88040.1 - 0.066 13.2 0.8 1 9.4 1.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 ParA PF10609.4 KZN88041.1 - 7.2e-36 121.9 0.0 2.2e-35 120.3 0.0 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KZN88041.1 - 8.8e-17 61.1 0.0 1.2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KZN88041.1 - 1.4e-06 28.3 0.0 5.7e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KZN88041.1 - 6.3e-06 25.4 1.1 0.00035 19.7 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 KZN88041.1 - 0.00084 18.5 0.0 0.0021 17.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KZN88041.1 - 0.0014 18.3 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN88041.1 - 0.0099 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN88041.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KZN88041.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 KZN88041.1 - 0.047 12.8 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.1 KZN88041.1 - 0.069 13.9 0.0 0.14 12.9 0.0 1.7 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.1 KZN88041.1 - 0.13 12.0 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KZN88041.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KZN88041.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 KZN88041.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zn_Tnp_IS1595 PF12760.2 KZN88041.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Exo_endo_phos PF03372.18 KZN88042.1 - 3.6e-09 36.9 1.2 5e-09 36.4 0.8 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 KZN88042.1 - 0.00055 19.8 0.2 0.001 18.9 0.2 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain NusB PF01029.13 KZN88044.1 - 0.031 14.2 1.6 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 NusB family SNARE PF05739.14 KZN88046.1 - 1.1e-12 47.4 3.2 3.4e-12 45.8 2.2 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KZN88046.1 - 0.0051 16.9 0.9 0.015 15.4 0.0 2.1 2 1 0 2 2 2 1 Syntaxin DUF1664 PF07889.7 KZN88046.1 - 0.085 12.6 0.9 0.17 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 KZN88046.1 - 0.11 12.8 2.1 2.7 8.3 0.1 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Synaptobrevin PF00957.16 KZN88046.1 - 0.12 12.0 0.9 0.34 10.5 0.6 1.8 1 0 0 1 1 1 0 Synaptobrevin DUF607 PF04678.8 KZN88046.1 - 0.14 12.1 0.1 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 FlxA PF14282.1 KZN88046.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 FlxA-like protein HrpB7 PF09486.5 KZN88046.1 - 8.3 6.3 9.6 0.2 11.5 0.2 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) zf-TRAF PF02176.13 KZN88047.1 - 1.9e-13 50.5 20.3 3.7e-09 36.8 2.0 4.1 1 1 3 4 4 4 4 TRAF-type zinc finger zf-C3HC4 PF00097.20 KZN88047.1 - 4.1e-07 29.5 10.5 4.1e-07 29.5 7.3 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN88047.1 - 6.8e-07 29.0 11.6 6.8e-07 29.0 8.0 3.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 KZN88047.1 - 1e-06 28.3 6.9 4e-06 26.4 4.8 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KZN88047.1 - 2.1e-06 27.4 12.9 2.1e-06 27.4 8.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KZN88047.1 - 2e-05 24.2 10.4 2e-05 24.2 7.2 3.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KZN88047.1 - 2.1e-05 24.4 11.8 2.1e-05 24.4 8.2 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN88047.1 - 5.3e-05 22.8 10.0 5.3e-05 22.8 6.9 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TraP PF07296.6 KZN88047.1 - 0.031 13.2 0.6 0.063 12.2 0.4 1.4 1 0 0 1 1 1 0 TraP protein Sina PF03145.11 KZN88047.1 - 0.18 11.4 18.1 0.16 11.6 0.4 3.0 1 1 3 4 4 4 0 Seven in absentia protein family Fungal_trans PF04082.13 KZN88048.1 - 2e-16 59.6 0.5 3.4e-16 58.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88048.1 - 3.6e-11 42.7 5.9 7.6e-11 41.7 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Het-C PF07217.6 KZN88051.1 - 3.1e-286 950.4 0.0 5.4e-286 949.6 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PhyH PF05721.8 KZN88052.1 - 3.4e-10 40.3 0.3 8.4e-10 39.0 0.2 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.13 KZN88053.1 - 2.3e-09 37.0 7.5 3.4e-09 36.4 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KZN88054.1 - 5.6e-20 71.6 0.0 1.2e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88054.1 - 1.1e-10 42.0 0.0 1.7e-09 38.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88054.1 - 7.5e-10 38.5 0.0 9.4e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN88054.1 - 3.7e-08 33.7 0.0 1.7e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN88054.1 - 9.2e-08 32.4 0.0 2.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN88054.1 - 0.00068 18.7 0.0 0.0023 16.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KZN88054.1 - 0.0015 18.8 0.0 0.0047 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KZN88054.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KZN88054.1 - 0.0056 16.6 0.0 0.048 13.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN88054.1 - 0.018 14.1 0.0 0.3 10.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KZN88054.1 - 0.031 13.3 0.0 0.076 12.0 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KZN88054.1 - 0.031 13.6 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain UPF0146 PF03686.8 KZN88054.1 - 0.042 13.6 0.0 0.89 9.3 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_16 PF10294.4 KZN88054.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase IBN_N PF03810.14 KZN88055.1 - 6.6e-08 32.3 0.2 6.6e-08 32.3 0.1 3.2 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KZN88055.1 - 3.3e-05 23.8 1.0 0.03 14.2 0.0 4.7 4 2 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KZN88055.1 - 0.00031 19.1 0.0 0.00066 18.1 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Proteasom_PSMB PF10508.4 KZN88055.1 - 0.0014 17.0 0.0 0.36 9.0 0.0 2.6 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit HORMA PF02301.13 KZN88056.1 - 1.2e-26 93.4 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Acetyltransf_7 PF13508.1 KZN88057.1 - 7.8e-07 29.1 0.1 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN88057.1 - 6.9e-05 22.7 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KZN88057.1 - 0.00019 21.2 0.1 0.00092 19.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN88057.1 - 0.0079 16.3 0.1 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN88057.1 - 0.015 15.4 0.1 0.056 13.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN88057.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 KZN88057.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2036 PF09724.4 KZN88058.1 - 9.1e-13 48.0 0.0 2.4e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Anp1 PF03452.9 KZN88059.1 - 1.9e-120 401.1 0.0 2.6e-120 400.6 0.0 1.2 1 0 0 1 1 1 1 Anp1 adh_short PF00106.20 KZN88060.1 - 9.8e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN88060.1 - 3.1e-09 36.7 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN88060.1 - 0.0037 16.7 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 KZN88061.1 - 3.6e-27 94.2 0.1 6.4e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88061.1 - 1.1e-25 89.6 1.1 1.7e-25 89.0 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KZN88061.1 - 8.2e-07 28.5 0.0 4.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated bZIP_1 PF00170.16 KZN88062.1 - 1.7e-07 31.0 7.9 2.6e-07 30.5 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KZN88062.1 - 0.00013 22.1 4.8 0.0002 21.5 3.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 KZN88062.1 - 0.00032 20.4 8.5 0.00047 19.9 5.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF2353 PF09789.4 KZN88062.1 - 0.012 14.8 1.3 0.017 14.4 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3432 PF11914.3 KZN88062.1 - 0.022 14.7 6.8 0.022 14.7 4.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3432) Ank_2 PF12796.2 KZN88063.1 - 1.1e-27 96.1 0.4 5.8e-08 32.9 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN88063.1 - 6.9e-25 86.9 0.3 1.3e-05 25.5 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN88063.1 - 1.4e-19 69.6 2.1 0.00085 19.5 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KZN88063.1 - 7.8e-19 66.4 1.2 0.0017 18.1 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KZN88063.1 - 8.3e-18 62.7 0.1 0.1 12.9 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeat F-box-like PF12937.2 KZN88063.1 - 8.1e-06 25.4 1.5 0.00014 21.5 0.1 2.9 2 1 1 3 3 3 1 F-box-like F-box PF00646.28 KZN88063.1 - 0.0036 16.9 0.2 0.011 15.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.2 KZN88064.1 - 4.5e-26 91.0 0.0 1.7e-08 34.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN88064.1 - 3.4e-23 81.5 0.3 8.3e-07 29.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN88064.1 - 3.3e-18 65.2 0.1 0.0061 16.7 0.0 4.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KZN88064.1 - 2.3e-16 58.6 9.4 0.0001 21.9 0.0 6.7 6 1 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 KZN88064.1 - 1.2e-14 52.9 0.0 0.0085 16.2 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat tRNA_bind PF01588.15 KZN88065.1 - 1.8e-22 79.0 0.1 1.9e-20 72.4 0.0 2.4 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KZN88065.1 - 2.2e-08 34.4 0.0 7.3e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN88065.1 - 3.4e-05 23.6 0.0 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN88065.1 - 0.028 14.4 0.2 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 KZN88065.1 - 0.058 11.9 2.5 0.085 11.3 1.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 KZN88065.1 - 3.2 7.5 8.2 5 6.9 5.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp PF00026.18 KZN88066.1 - 6.2e-62 209.6 0.2 9.5e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KZN88066.1 - 2.9e-06 27.6 0.1 0.093 13.2 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KZN88066.1 - 0.00054 19.9 0.0 0.0019 18.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KZN88066.1 - 0.0097 15.4 0.0 0.078 12.5 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KZN88066.1 - 0.078 12.8 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4452 PF14618.1 KZN88067.1 - 1.1e-68 230.2 8.9 1.1e-68 230.2 6.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.18 KZN88068.1 - 1.2e-10 40.9 0.1 4.7e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mito_carr PF00153.22 KZN88069.1 - 2.3e-67 222.7 4.4 6.9e-22 76.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KZN88069.1 - 9.3e-24 83.3 3.4 6.6e-13 48.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KZN88069.1 - 1.2e-22 77.3 3.6 7.3e-06 24.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KZN88069.1 - 1.5e-17 61.7 5.4 0.00027 20.5 0.0 4.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KZN88069.1 - 1.5e-16 58.8 4.6 3.6e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KZN88069.1 - 4.8e-16 58.1 1.6 1e-07 31.4 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KZN88069.1 - 2.1e-06 27.7 0.0 0.0049 16.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 KZN88069.1 - 0.12 12.0 0.0 21 4.8 0.0 3.0 3 0 0 3 3 3 0 EF hand GST_N_2 PF13409.1 KZN88070.1 - 8.1e-23 80.2 0.0 2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN88070.1 - 3.1e-18 65.4 0.1 8.8e-18 63.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN88070.1 - 4.2e-08 33.0 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN88070.1 - 2.2e-06 28.0 0.0 4.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN88070.1 - 5e-06 26.6 0.4 0.00036 20.6 0.1 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain ThiF PF00899.16 KZN88071.1 - 1.2e-51 174.1 0.0 2.7e-29 101.7 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KZN88071.1 - 5.8e-40 134.7 0.7 5.4e-26 89.9 0.1 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KZN88071.1 - 3.8e-38 130.4 0.0 9.2e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KZN88071.1 - 6.1e-24 83.1 1.5 3.6e-21 74.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Spc97_Spc98 PF04130.8 KZN88072.1 - 2e-80 270.6 0.0 2.9e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family adh_short PF00106.20 KZN88073.1 - 9.4e-27 93.9 1.0 1.3e-26 93.5 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88073.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88073.1 - 2e-14 53.6 0.2 3.3e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KZN88073.1 - 0.03 13.0 0.0 0.06 12.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lipocalin_3 PF12702.2 KZN88073.1 - 0.054 13.5 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like NAD_binding_10 PF13460.1 KZN88073.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 KZN88073.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.24 KZN88074.1 - 1.6e-19 70.0 0.0 3.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KZN88074.1 - 6e-09 35.9 0.0 4.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KZN88074.1 - 3.3e-06 26.8 0.1 9.8e-06 25.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KZN88074.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CVNH PF08881.5 KZN88075.1 - 7.3e-09 35.7 0.3 8.4e-09 35.6 0.2 1.1 1 0 0 1 1 1 1 CVNH domain DUF2839 PF10999.3 KZN88076.1 - 0.76 9.8 2.3 1.4 8.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) FAD_binding_4 PF01565.18 KZN88077.1 - 2.5e-17 62.6 0.1 5.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN88077.1 - 1.9e-09 37.2 0.4 4.8e-09 35.9 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KZN88077.1 - 0.027 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.11 KZN88078.1 - 6.7e-35 120.4 25.8 6.7e-35 120.4 17.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily C5-epim_C PF06662.8 KZN88079.1 - 0.013 14.8 0.6 0.09 12.0 0.1 2.0 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus GILT PF03227.11 KZN88080.1 - 2.7e-09 36.8 0.3 1.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.11 KZN88081.1 - 3.7e-31 108.2 0.0 3.3e-25 88.6 0.0 2.7 3 0 0 3 3 3 2 Hexokinase Hexokinase_1 PF00349.16 KZN88081.1 - 3.9e-28 98.1 0.0 2.7e-26 92.1 0.0 2.9 1 1 0 1 1 1 1 Hexokinase DUF4175 PF13779.1 KZN88082.1 - 0.62 7.7 5.7 0.71 7.5 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA_gamma_C PF02751.9 KZN88083.1 - 1.9e-27 94.8 2.7 2.7e-27 94.3 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KZN88083.1 - 4.2e-25 87.0 0.2 5.9e-25 86.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Dabb PF07876.7 KZN88086.1 - 1.2e-23 83.3 0.0 1.4e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TPR_12 PF13424.1 KZN88087.1 - 2.8e-15 55.9 9.6 9.8e-08 31.8 0.5 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88087.1 - 2.9e-05 24.3 11.0 1.7 9.4 0.1 6.0 4 2 3 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN88087.1 - 0.00029 20.9 1.2 0.24 11.5 0.4 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KZN88087.1 - 0.00042 19.8 3.0 0.38 10.4 0.1 3.7 2 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KZN88087.1 - 0.001 18.6 0.1 1.5 8.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88087.1 - 0.0046 17.2 3.1 5.5 7.4 0.1 3.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN88087.1 - 0.032 14.1 7.9 3.1 7.9 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 KZN88087.1 - 0.045 12.9 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 KZN88087.1 - 1.2 9.2 9.5 13 5.8 0.1 4.9 4 2 0 5 5 5 0 Tetratricopeptide repeat LigT_PEase PF02834.11 KZN88088.1 - 0.0011 18.8 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 LigT like Phosphoesterase AKAP7_NLS PF10469.4 KZN88088.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Aldedh PF00171.17 KZN88089.1 - 3e-133 444.5 0.1 3.3e-133 444.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN88089.1 - 6.9e-08 31.6 0.0 1.5e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ATP-synt_D PF01813.12 KZN88089.1 - 0.016 14.7 0.2 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 ATP synthase subunit D Methyltransf_33 PF10017.4 KZN88090.1 - 1.1e-26 93.2 0.0 3e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KZN88090.1 - 9.4e-20 71.0 1.3 1.7e-19 70.1 0.9 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KZN88090.1 - 2.1e-08 34.5 1.7 5.7e-08 33.1 1.1 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KZN88090.1 - 0.005 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TPR_11 PF13414.1 KZN88091.1 - 0.02 14.5 0.0 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 TPR repeat DUF605 PF04652.11 KZN88092.1 - 0.00085 18.8 7.8 0.0012 18.2 5.4 1.2 1 0 0 1 1 1 1 Vta1 like PHO4 PF01384.15 KZN88093.1 - 4.3e-101 337.8 18.9 5e-101 337.6 13.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Syndecan PF01034.15 KZN88093.1 - 0.031 13.9 0.0 0.2 11.3 0.0 2.4 1 0 0 1 1 1 0 Syndecan domain DUF486 PF04342.7 KZN88093.1 - 0.059 13.4 0.6 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF486 PgpA PF04608.8 KZN88093.1 - 3 7.6 8.0 0.53 10.0 0.6 2.9 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A 7TMR-DISM_7TM PF07695.6 KZN88093.1 - 4.8 6.7 15.0 4.1 7.0 0.1 3.9 3 1 0 3 3 3 0 7TM diverse intracellular signalling E1-E2_ATPase PF00122.15 KZN88094.1 - 4.4e-58 196.0 0.1 4.4e-58 196.0 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN88094.1 - 4.7e-44 150.1 7.8 4.7e-44 150.1 5.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN88094.1 - 5.6e-25 89.0 0.0 1.8e-24 87.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN88094.1 - 1.1e-17 63.6 0.0 2.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN88094.1 - 4.4e-16 59.6 0.0 2e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN88094.1 - 1.4e-06 27.6 0.7 9.2e-06 25.0 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus YjgP_YjgQ PF03739.9 KZN88094.1 - 0.00059 18.6 2.9 0.0021 16.8 2.0 1.9 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Hydrolase_3 PF08282.7 KZN88094.1 - 0.014 14.9 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DevR PF01905.11 KZN88094.1 - 0.048 12.4 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF202 PF02656.10 KZN88094.1 - 0.34 11.1 0.0 0.34 11.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) TPR_10 PF13374.1 KZN88095.1 - 9.4e-87 282.7 1.4 1.2e-12 47.3 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KZN88095.1 - 9.2e-84 275.4 10.6 3.7e-15 55.6 0.0 6.0 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KZN88095.1 - 9.7e-19 65.6 6.6 0.014 15.1 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_4 PF07721.9 KZN88095.1 - 7.7e-15 53.7 8.4 0.0021 18.3 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN88095.1 - 3e-14 51.9 1.3 0.14 11.8 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN88095.1 - 4.1e-14 51.5 3.6 1.3 9.4 0.0 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KZN88095.1 - 4.6e-14 51.1 6.5 0.028 14.3 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88095.1 - 4.2e-13 49.5 6.3 0.001 19.7 0.2 5.7 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN88095.1 - 6.3e-13 48.1 1.9 0.082 12.5 0.0 5.6 2 1 5 7 7 7 6 TPR repeat TPR_8 PF13181.1 KZN88095.1 - 1.4e-10 40.1 2.7 2 8.3 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88095.1 - 6.9e-10 39.1 3.3 4.3 7.7 0.1 6.4 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88095.1 - 7.1e-09 35.5 14.7 0.35 11.6 0.4 6.7 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN88095.1 - 3.8e-05 23.8 16.7 1.9 9.1 0.0 7.3 8 1 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN88095.1 - 5.2e-05 23.2 0.0 0.4 10.8 0.0 3.9 1 1 4 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KZN88095.1 - 0.0067 16.3 0.0 6.7 6.9 0.0 4.5 4 0 0 4 4 4 1 PPR repeat DUF2664 PF10867.3 KZN88095.1 - 0.0091 16.5 1.4 15 6.3 0.0 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF2664) Rab5-bind PF09311.6 KZN88095.1 - 0.063 13.1 1.9 36 4.1 0.0 4.0 3 1 0 3 3 3 0 Rabaptin-like protein DUF3366 PF11846.3 KZN88095.1 - 0.19 11.6 3.3 14 5.4 0.1 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) DUF1897 PF09005.5 KZN88095.1 - 1.8 8.1 6.8 19 4.7 0.1 4.6 6 0 0 6 6 5 0 Domain of unknown function (DUF1897) Na_Ca_ex PF01699.19 KZN88096.1 - 1.2e-17 63.8 24.1 2.5e-11 43.3 8.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein WND PF07861.6 KZN88096.1 - 0.0042 16.1 5.4 0.1 11.6 3.7 2.3 1 1 0 1 1 1 1 WisP family N-Terminal Region Na_Ca_ex PF01699.19 KZN88097.1 - 4.8e-19 68.3 21.7 7.7e-11 41.7 3.7 2.7 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF3784 PF12650.2 KZN88097.1 - 0.027 14.4 0.8 0.027 14.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) TetM_leader PF08076.6 KZN88097.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide zf-DHHC PF01529.15 KZN88097.1 - 0.23 10.8 1.1 0.6 9.4 0.7 1.8 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sdh_cyt PF01127.17 KZN88097.1 - 0.26 11.1 0.1 0.26 11.1 0.1 3.4 3 1 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Na_Ca_ex PF01699.19 KZN88098.1 - 1.3e-36 125.2 33.8 4e-21 75.0 5.4 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein TMEM154 PF15102.1 KZN88099.1 - 3.7e-05 23.4 1.6 4e-05 23.3 1.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family ASFV_J13L PF05568.6 KZN88099.1 - 0.0001 21.9 0.1 0.00011 21.7 0.1 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein SP_C-Propep PF08999.5 KZN88099.1 - 0.00011 21.5 0.1 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.1 KZN88099.1 - 0.014 15.7 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 KZN88099.1 - 0.016 15.3 0.3 0.02 15.0 0.2 1.1 1 0 0 1 1 1 0 Virus attachment protein p12 family RCR PF12273.3 KZN88099.1 - 0.02 15.4 0.3 0.025 15.1 0.2 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4079 PF13301.1 KZN88099.1 - 0.021 14.8 0.0 0.021 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) ODV-E18 PF10717.4 KZN88099.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4010 PF13194.1 KZN88099.1 - 0.024 13.9 0.1 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF3377 PF11857.3 KZN88099.1 - 0.029 13.9 0.9 0.04 13.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Baculo_11_kDa PF06143.6 KZN88099.1 - 0.041 13.2 1.1 0.055 12.8 0.8 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family Sulfate_transp PF00916.15 KZN88099.1 - 0.047 12.6 0.2 0.049 12.6 0.1 1.0 1 0 0 1 1 1 0 Sulfate transporter family DUF3328 PF11807.3 KZN88099.1 - 0.051 13.2 0.0 0.058 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) YajC PF02699.10 KZN88099.1 - 0.054 13.1 0.3 0.074 12.7 0.2 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit OSTbeta PF15048.1 KZN88099.1 - 0.1 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2207 PF09972.4 KZN88099.1 - 0.11 11.1 0.4 0.12 10.9 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1510 PF07423.6 KZN88099.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MSC PF09402.5 KZN88099.1 - 0.13 10.9 0.9 0.15 10.7 0.6 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4448 PF14610.1 KZN88099.1 - 0.13 11.7 1.3 0.17 11.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Vpu PF00558.14 KZN88099.1 - 0.16 11.5 0.5 0.21 11.1 0.3 1.1 1 0 0 1 1 1 0 Vpu protein SHP PF03579.8 KZN88099.1 - 0.17 11.2 0.4 0.21 10.9 0.2 1.1 1 0 0 1 1 1 0 Small hydrophobic protein Peptidase_S49_N PF08496.5 KZN88099.1 - 0.22 11.2 0.8 0.26 11.0 0.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rifin_STEVOR PF02009.11 KZN88099.1 - 0.28 10.7 8.7 0.34 10.5 6.0 1.0 1 0 0 1 1 1 0 Rifin/stevor family DUF92 PF01940.11 KZN88101.1 - 7.1e-59 198.6 12.2 8.8e-59 198.3 8.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Fungal_trans PF04082.13 KZN88102.1 - 7.7e-37 126.5 0.0 1.6e-36 125.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88102.1 - 2.1e-09 37.1 9.0 3.6e-09 36.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol PF00940.14 KZN88104.1 - 3e-167 556.1 0.0 4.1e-167 555.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KZN88104.1 - 2.2e-77 260.4 0.2 3.5e-77 259.7 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Filo_glycop PF01611.11 KZN88104.1 - 0.17 10.6 0.7 0.69 8.6 0.2 2.1 2 0 0 2 2 2 0 Filovirus glycoprotein Sin_N PF04801.8 KZN88105.1 - 1.4e-25 90.0 3.0 1.1e-24 87.1 2.0 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region MFS_1 PF07690.11 KZN88108.1 - 9e-38 129.8 20.1 9e-38 129.8 13.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.1 KZN88108.1 - 0.06 13.3 2.7 0.14 12.1 0.4 2.4 2 0 0 2 2 2 0 Stage V sporulation protein AB PepSY_TM_1 PF13172.1 KZN88108.1 - 1.9 8.3 6.1 0.79 9.5 0.7 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix OPT PF03169.10 KZN88109.1 - 0.014 13.8 0.0 0.016 13.7 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Rhabdo_glycop PF00974.13 KZN88109.1 - 0.014 13.6 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Abhydrolase_3 PF07859.8 KZN88110.1 - 2.7e-29 102.2 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN88110.1 - 6.5e-14 51.3 0.0 2.3e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KZN88110.1 - 0.00054 19.2 0.0 0.004 16.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN88110.1 - 0.0049 16.6 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family NIR_SIR PF01077.17 KZN88111.1 - 4.4e-50 169.0 0.0 9.2e-43 145.3 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KZN88111.1 - 1.2e-27 95.3 0.0 3.5e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KZN88111.1 - 4.6e-26 91.5 0.0 9.2e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KZN88111.1 - 1.3e-07 31.3 0.1 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KZN88112.1 - 5.3e-60 202.3 2.2 7.1e-60 201.9 1.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MmgE_PrpD PF03972.9 KZN88113.1 - 9.8e-101 337.0 3.2 1.2e-100 336.8 2.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1900 PF08954.6 KZN88113.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) DUF2891 PF11199.3 KZN88113.1 - 0.13 10.8 1.7 4.7 5.7 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2891) Ras PF00071.17 KZN88114.1 - 2.3e-59 199.3 0.2 3e-59 199.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN88114.1 - 7.5e-21 74.8 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN88114.1 - 1.2e-17 63.7 0.1 1.5e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN88114.1 - 2.3e-07 30.4 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN88114.1 - 3.9e-06 26.1 0.1 4.9e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KZN88114.1 - 5e-06 25.8 0.0 8.2e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KZN88114.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KZN88114.1 - 0.024 14.4 0.1 2.9 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KZN88114.1 - 0.048 13.5 0.2 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN88114.1 - 0.048 12.8 0.2 1.2 8.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN88114.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN88114.1 - 0.15 11.9 0.0 3.3 7.6 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain ATP-synt_C PF00137.16 KZN88115.1 - 2.2e-27 94.7 27.1 6.9e-17 61.1 4.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Lysis_S PF04971.7 KZN88115.1 - 0.13 11.9 1.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Lysis protein S Oxidored_q2 PF00420.19 KZN88115.1 - 1.4 8.5 5.8 0.74 9.4 1.0 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 KZN88116.1 - 4e-48 162.4 0.0 1.7e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KZN88116.1 - 3.8e-35 120.6 1.0 5.6e-35 120.0 0.7 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KZN88116.1 - 7.8e-14 51.3 0.2 2.3e-13 49.8 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) NicO PF03824.11 KZN88116.1 - 0.83 8.9 4.5 1.4 8.2 3.2 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein BAF1_ABF1 PF04684.8 KZN88116.1 - 1.1 8.0 9.9 1.6 7.4 6.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 KZN88116.1 - 6.1 6.1 12.0 9.3 5.5 8.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDHD PF02862.12 KZN88117.1 - 1.1e-44 152.9 2.1 4.1e-42 144.5 0.0 3.3 2 2 0 2 2 2 1 DDHD domain Abhydrolase_5 PF12695.2 KZN88117.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN88117.1 - 0.024 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3909 PF13077.1 KZN88118.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) FAD_binding_3 PF01494.14 KZN88119.1 - 3.1e-71 240.2 0.0 4e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KZN88119.1 - 3.6e-39 134.0 0.0 6e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KZN88119.1 - 0.0074 15.2 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN88119.1 - 0.0088 16.4 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN88119.1 - 0.015 14.2 0.1 0.061 12.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN88119.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN88119.1 - 0.035 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 KZN88119.1 - 0.059 11.6 0.0 0.092 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 KZN88119.1 - 0.063 13.1 0.0 0.27 11.0 0.0 2.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KZN88119.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF866 PF05907.8 KZN88120.1 - 3.6e-46 156.5 0.1 3.9e-46 156.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 KZN88120.1 - 0.042 13.4 1.0 0.072 12.7 0.7 1.5 1 1 0 1 1 1 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 KZN88120.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) LSM PF01423.17 KZN88121.1 - 6.5e-19 67.2 0.0 7.6e-19 67.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN88121.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2612 PF11041.3 KZN88121.1 - 0.051 13.1 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) RTA1 PF04479.8 KZN88123.1 - 3e-52 177.3 10.4 3.9e-52 176.9 7.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF687 PF05095.7 KZN88123.1 - 0.016 13.6 1.2 0.025 12.9 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF687) Herpes_pp38 PF04846.8 KZN88123.1 - 0.049 12.9 0.6 0.11 11.8 0.4 1.6 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF3493 PF11998.3 KZN88123.1 - 0.052 13.4 8.4 0.089 12.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Cation_ATPase_C PF00689.16 KZN88123.1 - 0.5 9.8 15.4 0.47 9.9 2.4 2.6 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus TMEM138 PF14935.1 KZN88123.1 - 0.57 10.5 7.7 0.68 10.2 0.5 3.0 2 1 1 3 3 3 0 Transmembrane protein 138 DASH_Dad1 PF08649.5 KZN88124.1 - 3.1e-23 81.2 2.1 4e-23 80.8 1.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Ras PF00071.17 KZN88125.1 - 1.8e-48 164.0 0.0 2.3e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN88125.1 - 2.8e-12 47.1 0.0 4.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN88125.1 - 2.7e-05 23.4 0.0 0.00016 20.9 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KZN88125.1 - 0.041 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KZN88125.1 - 0.047 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 KZN88126.1 - 2.6e-15 56.2 2.9 2.6e-15 56.2 2.0 2.2 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_C48 PF02902.14 KZN88127.1 - 6.8e-25 87.9 0.0 1.3e-24 87.0 0.0 1.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain zf-HIT PF04438.11 KZN88128.1 - 2e-10 40.1 9.6 2e-10 40.1 6.7 1.6 2 0 0 2 2 2 1 HIT zinc finger Btz PF09405.5 KZN88128.1 - 0.031 14.3 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding adh_short PF00106.20 KZN88129.1 - 3.7e-17 62.7 0.1 4.7e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88129.1 - 6.2e-09 35.9 0.0 7.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88129.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KZN88129.1 - 0.00025 20.2 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Toprim_3 PF13362.1 KZN88129.1 - 0.025 14.8 0.0 0.062 13.5 0.0 1.7 2 0 0 2 2 2 0 Toprim domain DUF460 PF04312.8 KZN88129.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) WD40 PF00400.27 KZN88130.1 - 0.078 12.8 3.1 0.051 13.4 0.2 2.2 3 0 0 3 3 3 0 WD domain, G-beta repeat DAO PF01266.19 KZN88131.1 - 1e-18 67.3 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase zf-CCCH PF00642.19 KZN88132.1 - 3.1e-05 23.5 2.7 3.1e-05 23.5 1.9 2.8 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CS PF04969.11 KZN88133.1 - 7.6e-10 39.2 0.3 1.2e-09 38.5 0.2 1.4 1 1 0 1 1 1 1 CS domain Xol-1_GHMP-like PF09109.5 KZN88133.1 - 0.15 12.1 1.3 0.24 11.4 0.9 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like Snf7 PF03357.16 KZN88134.1 - 9.6e-21 73.9 12.1 9.6e-21 73.9 8.4 1.7 1 1 1 2 2 2 1 Snf7 PSD4 PF07631.6 KZN88134.1 - 0.096 13.0 1.2 0.17 12.2 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) DNA_pol_viral_N PF00242.12 KZN88134.1 - 0.38 9.7 3.5 0.44 9.5 2.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain GAS PF13851.1 KZN88134.1 - 1.1 8.3 8.0 0.3 10.2 2.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BMFP PF04380.8 KZN88134.1 - 1.2 9.3 13.6 0.47 10.6 0.8 4.3 3 1 1 4 4 4 0 Membrane fusogenic activity Wbp11 PF09429.5 KZN88134.1 - 2.1 8.3 12.1 0.24 11.4 1.7 2.9 2 1 1 3 3 3 0 WW domain binding protein 11 Tnp_P_element_C PF12596.3 KZN88134.1 - 2.5 8.4 5.7 17 5.7 0.1 2.7 2 1 1 3 3 3 0 87kDa Transposase AAA_13 PF13166.1 KZN88134.1 - 8 4.7 10.2 2.9 6.2 3.0 1.8 1 1 0 2 2 2 0 AAA domain ING PF12998.2 KZN88134.1 - 9.2 6.5 8.5 8.7 6.6 2.7 2.8 1 1 3 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding RRM_1 PF00076.17 KZN88135.1 - 2.4e-15 55.9 0.0 4.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN88135.1 - 8.6e-12 44.8 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN88135.1 - 9.6e-05 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KZN88135.1 - 0.00012 22.4 1.7 0.00012 22.4 1.2 2.8 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 HSP33 PF01430.14 KZN88135.1 - 0.045 12.8 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein EVI2A PF05399.6 KZN88135.1 - 0.24 10.6 1.5 0.73 9.0 0.6 1.9 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) EF-hand_8 PF13833.1 KZN88136.1 - 0.0017 17.9 0.0 0.33 10.6 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KZN88136.1 - 0.0055 16.4 0.6 1.2 9.1 0.0 3.6 4 1 0 4 4 4 1 EF-hand domain RuvA_C PF07499.8 KZN88136.1 - 0.087 13.0 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 RuvA, C-terminal domain PUL PF08324.6 KZN88137.1 - 2.9e-38 131.1 0.0 5e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KZN88137.1 - 4.9e-33 114.0 0.0 8e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KZN88137.1 - 2e-15 56.3 0.0 3.9e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KZN88137.1 - 5.8e-05 23.2 0.1 0.00033 20.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KZN88137.1 - 0.0012 18.5 0.0 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 KZN88137.1 - 0.007 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 KZN88137.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 KZN88137.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin DUF2847 PF11009.3 KZN88137.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) 2-Hacid_dh_C PF02826.14 KZN88138.1 - 3.8e-37 127.1 0.0 5.3e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN88138.1 - 1.2e-20 73.3 0.0 1.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 KZN88138.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 KZN88138.1 - 0.013 15.3 2.8 0.019 14.8 0.5 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN88138.1 - 0.049 13.1 3.5 3.5 7.1 0.1 2.9 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KZN88138.1 - 0.13 11.8 1.4 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box PF00646.28 KZN88140.1 - 0.014 15.0 0.4 0.049 13.3 0.3 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KZN88140.1 - 0.022 14.4 0.7 0.039 13.6 0.1 1.7 2 0 0 2 2 2 0 F-box-like Alb1 PF09135.6 KZN88141.1 - 6.1e-30 104.0 13.5 9.1e-30 103.5 9.3 1.2 1 0 0 1 1 1 1 Alb1 Nop25 PF09805.4 KZN88141.1 - 0.3 11.1 9.3 0.5 10.4 6.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Vps16_N PF04841.8 KZN88142.1 - 3.9e-98 328.6 0.0 5.3e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KZN88142.1 - 1.2e-81 274.0 0.0 2.2e-81 273.2 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Bestrophin PF01062.16 KZN88144.1 - 3.7e-41 141.0 0.0 7.9e-41 139.9 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Desmo_N PF06771.6 KZN88144.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus DUF2510 PF10708.4 KZN88144.1 - 0.33 10.4 2.3 7.8 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) FHA PF00498.21 KZN88146.1 - 5.8e-14 51.9 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KZN88146.1 - 1.5e-06 27.9 9.1 3.1e-06 26.9 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN88146.1 - 0.00097 19.1 5.8 0.0022 18.0 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KZN88146.1 - 0.003 17.2 6.1 0.0058 16.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN88146.1 - 0.017 14.7 7.4 0.044 13.4 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88146.1 - 0.021 14.8 9.3 0.04 13.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN88146.1 - 0.036 13.8 2.8 0.08 12.7 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 KZN88146.1 - 0.23 11.4 5.6 0.62 10.1 3.9 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KZN88146.1 - 0.67 9.8 7.0 1.4 8.8 4.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Arm PF00514.18 KZN88147.1 - 9.1e-69 225.1 29.3 5e-13 48.3 0.1 11.3 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KZN88147.1 - 5.9e-24 84.1 12.6 2.2e-06 27.8 0.2 7.3 3 2 1 6 6 6 5 HEAT repeats HEAT PF02985.17 KZN88147.1 - 1.1e-20 71.8 14.2 0.016 15.2 0.0 9.6 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 KZN88147.1 - 3.6e-16 59.1 9.0 0.013 16.0 0.0 8.3 6 1 3 9 9 8 5 HEAT-like repeat Arm_2 PF04826.8 KZN88147.1 - 4.7e-12 45.5 5.7 0.0025 16.9 0.0 3.4 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 KZN88147.1 - 1.7e-11 43.1 5.9 1.2e-06 27.1 0.3 2.9 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 KZN88147.1 - 4.5e-10 38.1 0.4 7.7e-10 37.3 0.3 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KZN88147.1 - 9.7e-10 38.0 0.3 0.00018 20.7 0.4 3.5 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 KZN88147.1 - 0.0078 16.1 2.6 6.4 6.7 0.0 4.5 2 1 4 6 6 6 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 KZN88147.1 - 0.017 15.5 0.0 2.5 8.5 0.0 3.7 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 KZN88147.1 - 0.017 15.5 5.4 22 5.8 0.2 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat EXOSC1 PF10447.4 KZN88148.1 - 1.8e-28 98.3 1.2 2.6e-28 97.7 0.8 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KZN88148.1 - 2.8e-14 52.1 0.2 4.5e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CRISPR_Cse2 PF09485.5 KZN88148.1 - 0.03 14.3 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1423 PF07227.6 KZN88148.1 - 0.16 10.6 0.2 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) GTP_EFTU PF00009.22 KZN88149.1 - 1.6e-53 180.9 0.0 2.6e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KZN88149.1 - 2.5e-15 56.1 0.0 6.1e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KZN88149.1 - 4.2e-08 33.1 0.0 4.7e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KZN88149.1 - 1.4e-07 31.2 0.0 3.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KZN88149.1 - 0.0003 20.3 0.0 0.0035 16.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV DUF4604 PF15377.1 KZN88150.1 - 4.1e-23 82.3 17.3 4.7e-23 82.1 12.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) FLO_LFY PF01698.11 KZN88150.1 - 2.4 6.9 7.2 3 6.6 5.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 KZN88150.1 - 3 6.6 7.7 3.6 6.4 5.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tom37_C PF11801.3 KZN88150.1 - 9.2 6.0 6.8 8.9 6.1 4.1 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain WD40 PF00400.27 KZN88151.1 - 1e-18 66.3 3.9 5e-06 26.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KZN88151.1 - 1.5e-07 30.5 0.1 0.0054 15.5 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KZN88151.1 - 1.2e-05 25.1 0.1 0.027 14.1 0.0 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KZN88151.1 - 0.0036 15.6 0.1 0.033 12.4 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) HPS3_N PF14761.1 KZN88151.1 - 0.021 14.2 0.1 0.53 9.6 0.0 2.7 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 Cytochrom_D1 PF02239.11 KZN88151.1 - 0.046 12.0 0.7 0.8 7.9 0.1 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 KZN88151.1 - 5.6 7.3 10.7 1.9 8.8 0.2 3.7 4 0 0 4 4 4 0 PQQ-like domain zf-C3HC4_2 PF13923.1 KZN88152.1 - 0.00051 19.9 4.2 0.0012 18.8 3.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN88152.1 - 0.00053 19.7 1.2 0.00092 18.9 0.8 1.4 1 0 0 1 1 1 1 Ring finger domain FYVE PF01363.16 KZN88152.1 - 0.0029 17.4 2.4 0.0051 16.6 1.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_5 PF14634.1 KZN88152.1 - 0.011 15.3 5.3 0.02 14.6 3.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN88152.1 - 0.021 14.4 3.5 0.044 13.4 2.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 KZN88152.1 - 0.039 13.6 0.3 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4 PF00097.20 KZN88152.1 - 0.054 13.1 3.4 0.15 11.7 2.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) L51_S25_CI-B8 PF05047.11 KZN88153.1 - 2.6e-15 55.8 0.1 3.8e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 KZN88154.1 - 4e-32 110.3 3.1 7.6e-32 109.4 2.1 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KZN88154.1 - 3e-16 58.8 0.1 5.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN88154.1 - 3.7e-13 49.2 0.0 6.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN88154.1 - 3.6e-06 26.7 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 KZN88155.1 - 1.5e-17 63.2 0.0 3.4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribonuc_L-PSP PF01042.16 KZN88155.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Endoribonuclease L-PSP DUF3722 PF12519.3 KZN88156.1 - 5.8e-86 287.9 0.2 1.2e-85 286.9 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 KZN88157.1 - 1.2e-90 302.8 1.1 1.4e-90 302.6 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.17 KZN88157.1 - 0.01 15.4 0.2 4.7 6.8 0.1 2.8 2 1 1 3 3 3 0 DeoR C terminal sensor domain CutC PF03932.9 KZN88157.1 - 0.023 13.9 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 CutC family HGTP_anticodon PF03129.15 KZN88157.1 - 0.1 12.5 0.3 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Anticodon binding domain Pkinase PF00069.20 KZN88158.1 - 4.7e-11 42.3 0.3 3e-10 39.7 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88158.1 - 4.2e-06 26.0 0.1 7.7e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 KZN88158.1 - 0.0017 17.7 0.1 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Snf7 PF03357.16 KZN88159.1 - 3.3e-27 94.9 30.4 5e-14 52.0 9.8 2.7 2 1 1 3 3 3 2 Snf7 V_ATPase_I PF01496.14 KZN88159.1 - 0.13 10.1 2.5 0.15 9.8 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt_B PF00430.13 KZN88159.1 - 0.37 10.5 7.0 12 5.7 2.6 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) YlqD PF11068.3 KZN88159.1 - 1.8 8.5 14.0 1 9.3 4.3 2.2 2 0 0 2 2 2 0 YlqD protein Dynamin_N PF00350.18 KZN88160.1 - 1.6e-16 60.5 0.1 3.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KZN88160.1 - 1.2e-09 38.1 0.1 5.9e-09 35.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN88160.1 - 4.3e-07 29.5 0.2 5.2e-06 26.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KZN88160.1 - 0.0029 18.0 0.6 1.5 9.2 0.0 3.9 3 1 1 4 4 4 1 Miro-like protein IIGP PF05049.8 KZN88160.1 - 0.039 12.7 0.0 0.082 11.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 KZN88160.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 KZN88160.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 KZN88160.1 - 0.058 14.2 0.1 0.44 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.8 KZN88160.1 - 0.09 13.1 1.6 45 4.5 0.0 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PTCB-BRCT PF12738.2 KZN88161.1 - 7.3e-50 166.6 1.1 8.7e-23 79.9 0.1 4.9 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 KZN88161.1 - 2.8e-29 101.0 0.5 4.6e-14 52.3 0.1 4.6 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 KZN88162.1 - 8.1e-66 222.4 0.1 6.7e-51 173.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KZN88162.1 - 3.5e-17 62.6 0.0 6.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KZN88162.1 - 6.1e-07 29.6 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KZN88162.1 - 2.8e-05 22.1 0.1 0.00028 18.7 0.0 2.3 3 0 0 3 3 3 1 Helicase RNA_helicase PF00910.17 KZN88162.1 - 3.7e-05 23.8 0.3 0.029 14.5 0.0 2.8 2 1 0 2 2 2 1 RNA helicase UvrD_C_2 PF13538.1 KZN88162.1 - 5.7e-05 23.1 1.0 0.00067 19.7 0.1 2.9 2 1 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KZN88162.1 - 7.7e-05 22.3 0.2 0.00017 21.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KZN88162.1 - 0.0032 17.4 1.3 0.0062 16.5 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.24 KZN88162.1 - 0.0042 17.2 0.0 0.0088 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KZN88162.1 - 0.0055 15.9 0.3 0.032 13.4 0.1 2.1 1 1 1 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 KZN88162.1 - 0.0082 15.1 0.0 0.0082 15.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KZN88162.1 - 0.012 14.3 0.1 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 KZN88162.1 - 0.012 15.8 0.1 0.34 11.2 0.1 3.0 2 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.13 KZN88162.1 - 0.041 13.4 0.0 3.4 7.1 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KZN88162.1 - 0.051 13.0 0.3 0.79 9.1 0.1 2.3 2 1 0 2 2 2 0 AAA-like domain NACHT PF05729.7 KZN88162.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KZN88162.1 - 0.067 13.0 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.2 KZN88162.1 - 0.084 11.9 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 T2SE PF00437.15 KZN88162.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KZN88162.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KZN88162.1 - 0.14 11.5 0.0 19 4.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 KZN88162.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KZN88162.1 - 0.16 11.7 0.5 1.8 8.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 KZN88162.1 - 0.26 10.5 4.1 0.11 11.7 0.1 2.1 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 KZN88162.1 - 0.51 9.8 3.9 0.95 8.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KZN88162.1 - 0.58 9.8 3.1 0.54 9.9 0.4 2.2 1 1 1 2 2 2 0 Archaeal ATPase YjeF_N PF03853.10 KZN88163.1 - 9.1e-41 139.2 0.1 1.3e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KZN88163.1 - 6.5e-10 39.4 0.7 6.5e-10 39.4 0.5 2.1 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.18 KZN88163.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase F-box-like PF12937.2 KZN88166.1 - 6e-05 22.6 0.1 0.00015 21.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like PalH PF08733.5 KZN88167.1 - 1.5e-101 339.7 0.0 8.8e-101 337.2 0.0 1.9 1 1 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.1 KZN88167.1 - 1.2 9.1 4.5 4.3 7.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Asp PF00026.18 KZN88168.1 - 1.4e-75 254.4 8.0 2.2e-75 253.8 5.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KZN88168.1 - 6.5e-05 23.3 0.7 0.017 15.5 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KZN88168.1 - 0.0056 16.6 0.6 0.025 14.5 0.3 2.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KZN88168.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Zn_clus PF00172.13 KZN88169.1 - 4.5e-07 29.6 14.8 6.9e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.4 KZN88170.1 - 2.1e-22 79.4 0.3 3.2e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KZN88170.1 - 2.8e-05 23.3 0.1 9.5e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein Apg6 Mhr1 PF12829.2 KZN88171.1 - 6.5e-32 109.2 0.4 1.5e-31 108.0 0.3 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination PP2C PF00481.16 KZN88172.1 - 2e-62 210.8 2.2 3.6e-50 170.7 0.1 3.4 2 1 0 3 3 3 2 Protein phosphatase 2C Trp_syntA PF00290.15 KZN88173.1 - 2.8e-91 304.6 0.0 3.9e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KZN88173.1 - 3.3e-45 154.6 0.1 5.1e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPO1_KFDV PF12143.3 KZN88174.1 - 0.036 13.9 0.2 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Kdo PF06293.9 KZN88175.1 - 0.00021 20.4 0.1 0.00048 19.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN88175.1 - 0.00027 20.7 3.1 0.0035 17.1 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN88175.1 - 0.08 12.0 0.2 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.17 KZN88175.1 - 0.092 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family F-box PF00646.28 KZN88176.1 - 0.00023 20.7 0.2 0.0052 16.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KZN88176.1 - 0.00037 20.1 0.1 0.0009 18.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like BBIP10 PF14777.1 KZN88176.1 - 0.12 11.8 0.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 PRANC PF09372.5 KZN88176.1 - 3.2 7.7 5.5 0.54 10.2 0.5 2.2 3 1 0 3 3 3 0 PRANC domain Sigma70_r4_2 PF08281.7 KZN88180.1 - 2.7e-05 23.5 0.0 3.1 7.3 0.0 3.9 4 0 0 4 4 4 3 Sigma-70, region 4 MarR_2 PF12802.2 KZN88180.1 - 0.0013 18.3 1.4 16 5.2 0.1 3.9 2 1 1 3 3 3 1 MarR family HTH_38 PF13936.1 KZN88180.1 - 0.0025 17.3 0.6 5.8 6.5 0.0 3.5 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_5 PF01022.15 KZN88180.1 - 0.0062 16.1 0.0 59 3.4 0.0 4.2 4 0 0 4 4 4 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.14 KZN88180.1 - 0.0075 16.1 0.3 50 3.9 0.0 3.8 4 0 0 4 4 4 0 Iron dependent repressor, N-terminal DNA binding domain DUF3834 PF12916.2 KZN88180.1 - 0.03 13.3 0.7 15 4.5 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3834) HTH_AsnC-type PF13404.1 KZN88180.1 - 0.049 13.1 0.0 78 2.9 0.0 3.5 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Prok-E2_C PF14459.1 KZN88180.1 - 0.073 13.1 1.0 0.54 10.3 0.1 2.3 1 1 3 4 4 4 0 Prokaryotic E2 family C HTH_IclR PF09339.5 KZN88180.1 - 0.096 12.2 0.1 50 3.6 0.0 3.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF3328 PF11807.3 KZN88181.1 - 1e-33 116.8 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.2 KZN88182.1 - 4.2e-109 357.1 18.8 2.2e-17 63.1 0.2 16.0 4 4 9 16 16 16 15 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN88182.1 - 1.6e-90 296.0 22.2 4.1e-08 33.5 0.0 21.3 14 4 8 22 22 21 18 Ankyrin repeats (many copies) Ank PF00023.25 KZN88182.1 - 4.1e-85 275.6 37.1 8.9e-08 31.5 0.0 24.1 25 0 0 25 25 25 15 Ankyrin repeat Ank_3 PF13606.1 KZN88182.1 - 1.7e-68 219.6 21.2 3.5e-07 29.8 0.0 22.9 24 1 1 25 25 25 12 Ankyrin repeat Ank_5 PF13857.1 KZN88182.1 - 1.7e-64 212.3 28.3 2.6e-08 33.8 0.0 17.6 15 2 2 17 17 17 11 Ankyrin repeats (many copies) NACHT PF05729.7 KZN88182.1 - 7e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN88182.1 - 0.00077 19.4 0.0 0.0028 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KZN88182.1 - 0.0099 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KZN88182.1 - 0.027 14.2 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KZN88182.1 - 0.07 13.2 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KZN88182.1 - 0.091 12.5 0.0 0.89 9.3 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_35 PF14516.1 KZN88182.1 - 0.096 11.2 0.1 0.42 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain adh_short PF00106.20 KZN88183.1 - 0.014 15.3 0.2 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 KZN88183.1 - 0.069 12.5 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.21 KZN88184.1 - 7.4e-69 232.0 0.1 2.2e-68 230.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN88184.1 - 2.7e-59 199.8 0.3 2.7e-59 199.8 0.2 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KZN88184.1 - 1.2e-56 192.3 0.1 2.1e-56 191.5 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KZN88184.1 - 2.7e-51 174.4 0.2 5.2e-51 173.5 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KZN88184.1 - 2.7e-47 160.7 0.5 8.3e-47 159.2 0.3 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN88184.1 - 2.4e-38 130.6 0.2 6.8e-38 129.1 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN88184.1 - 1.6e-17 63.2 0.0 1.8e-16 59.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KZN88184.1 - 2.8e-15 56.5 0.0 7.1e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN88184.1 - 8e-12 45.1 0.0 2.2e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN88184.1 - 2.3e-10 41.4 0.2 5.2e-09 37.0 0.0 3.3 3 1 1 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KZN88184.1 - 1.7e-07 31.6 0.0 8.3e-07 29.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88184.1 - 3.8e-07 30.6 0.1 4e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88184.1 - 9.7e-07 28.4 0.0 2.7e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN88184.1 - 4.5e-06 26.6 0.6 2.6e-05 24.2 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN88184.1 - 1.5e-05 24.2 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KZN88184.1 - 2.2e-05 24.6 0.1 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 KZN88184.1 - 0.00015 21.5 0.3 0.00042 20.0 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 KZN88184.1 - 0.012 15.0 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Thiolase_N PF00108.18 KZN88184.1 - 0.042 12.8 0.1 0.088 11.7 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Shikimate_DH PF01488.15 KZN88184.1 - 0.3 11.1 0.0 0.83 9.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 KZN88185.1 - 3e-09 36.6 10.7 5.4e-09 35.8 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KZN88185.1 - 0.06 13.4 7.2 0.21 11.6 5.0 1.9 1 0 0 1 1 1 0 Opy2 protein adh_short PF00106.20 KZN88186.1 - 6.9e-13 48.8 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN88186.1 - 0.0011 18.7 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 KR domain GMC_oxred_N PF00732.14 KZN88187.1 - 3.7e-54 183.8 0.0 4.9e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN88187.1 - 6.3e-32 110.8 0.0 1.2e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN88187.1 - 6.8e-06 25.2 0.2 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN88187.1 - 0.00063 18.7 0.1 0.6 8.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN88187.1 - 0.012 15.6 0.2 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN88187.1 - 0.024 13.5 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN88187.1 - 0.025 14.4 0.1 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.21 KZN88189.1 - 3.3e-72 243.0 0.0 8e-72 241.7 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KZN88189.1 - 2.1e-71 240.5 0.0 3.3e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN88189.1 - 1.3e-58 198.8 0.0 2.3e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KZN88189.1 - 1.9e-58 197.1 0.1 4.6e-58 195.8 0.1 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KZN88189.1 - 2.1e-49 167.6 0.3 7.4e-49 165.8 0.2 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN88189.1 - 4.6e-29 100.6 0.1 1.2e-28 99.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KZN88189.1 - 1.6e-05 24.0 0.7 3.3e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KZN88189.1 - 2.6e-05 23.9 0.0 6.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88189.1 - 0.00092 18.7 0.1 0.0024 17.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KZN88189.1 - 0.0049 17.0 0.1 0.017 15.3 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site ACP_syn_III PF08545.5 KZN88189.1 - 0.021 14.4 0.4 0.069 12.8 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3Beta_HSD PF01073.14 KZN88189.1 - 0.071 11.7 0.0 0.16 10.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 7tm_1 PF00001.16 KZN88190.1 - 0.027 13.6 0.8 0.058 12.5 0.5 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Pyr_redox_3 PF13738.1 KZN88191.1 - 1e-27 97.5 0.0 4.2e-25 89.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN88191.1 - 2.5e-11 42.4 0.0 1.2e-07 30.3 0.0 2.4 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN88191.1 - 2.1e-10 40.0 0.1 2e-08 33.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN88191.1 - 2.2e-09 37.2 1.6 0.0013 18.5 0.2 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN88191.1 - 1.1e-06 28.5 0.0 3.5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN88191.1 - 4.5e-06 26.6 0.0 0.00052 19.9 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN88191.1 - 5e-05 22.3 1.1 0.56 9.0 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN88191.1 - 0.0021 16.5 0.0 1.2 7.5 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein Transferase PF02458.10 KZN88192.1 - 2.5e-12 45.9 0.0 7.4e-09 34.5 0.0 2.5 3 0 0 3 3 3 2 Transferase family adh_short_C2 PF13561.1 KZN88193.1 - 4.2e-18 65.9 0.0 5.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN88193.1 - 2.5e-17 63.3 4.0 4.4e-17 62.4 2.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN88193.1 - 3.6e-07 30.0 1.3 6.5e-07 29.1 0.9 1.4 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 KZN88193.1 - 0.084 13.0 0.2 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain FAD_binding_3 PF01494.14 KZN88194.1 - 1.1e-21 77.2 0.0 3e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KZN88194.1 - 7.3e-07 28.4 0.0 1.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KZN88194.1 - 1.9e-06 27.0 0.3 0.00098 18.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN88194.1 - 1.7e-05 24.7 1.9 4.7e-05 23.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN88194.1 - 0.00016 20.6 0.3 0.00025 20.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN88194.1 - 0.00061 19.9 0.2 0.0025 17.9 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN88194.1 - 0.0025 18.1 0.6 0.26 11.7 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN88194.1 - 0.0046 16.8 0.2 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN88194.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KZN88194.1 - 0.048 12.1 0.1 0.13 10.7 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KZN88194.1 - 0.052 13.3 0.1 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3237 PF11578.3 KZN88195.1 - 1.3e-14 53.8 0.0 1.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Pro_isomerase PF00160.16 KZN88196.1 - 6.6e-39 133.6 0.0 1.2e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KZN88196.1 - 6.4e-06 25.5 0.0 2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 KZN88196.1 - 0.00028 20.7 0.1 0.0019 18.1 0.0 2.3 1 1 0 2 2 2 1 U-box domain DUF1479 PF07350.7 KZN88197.1 - 4.1e-08 32.1 0.8 0.0017 16.9 0.0 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 KZN88197.1 - 3.5e-07 30.4 0.1 6.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 KZN88197.1 - 7.3e-07 28.3 2.9 1.2e-06 27.5 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3145 PF11343.3 KZN88198.1 - 0.042 13.2 0.1 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Methyltransf_PK PF05891.7 KZN88199.1 - 7.4e-72 241.1 0.0 8.7e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KZN88199.1 - 0.00016 22.1 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN88199.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CitG PF01874.11 KZN88199.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase TPT PF03151.11 KZN88200.1 - 1.3e-29 102.8 8.9 1.3e-29 102.8 6.2 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KZN88200.1 - 2.3e-07 30.0 18.9 1e-05 24.6 13.1 2.2 1 1 0 1 1 1 1 UAA transporter family DUF3377 PF11857.3 KZN88200.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MFS_1 PF07690.11 KZN88201.1 - 5e-15 55.0 15.5 5e-15 55.0 10.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KZN88201.1 - 0.67 10.0 8.2 0.065 13.2 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1228) UPF0052 PF01933.13 KZN88202.1 - 2.1e-55 188.2 0.0 2.7e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.1 KZN88203.1 - 6e-11 41.8 10.0 8.9e-11 41.2 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN88203.1 - 1.4e-09 37.4 9.0 2.9e-09 36.4 6.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88203.1 - 1.9e-09 37.3 11.5 3.3e-09 36.6 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN88203.1 - 2.9e-09 36.5 10.8 4.6e-09 35.9 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN88203.1 - 5.6e-07 29.1 11.7 1e-06 28.3 8.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KZN88203.1 - 5.4e-05 22.9 10.3 0.00033 20.4 7.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN88203.1 - 0.0005 19.7 9.0 0.00058 19.5 3.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 KZN88203.1 - 0.009 15.5 3.4 0.025 14.0 2.3 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KZN88203.1 - 0.015 15.2 7.9 0.042 13.8 5.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.9 KZN88203.1 - 0.024 14.1 1.1 0.27 10.7 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 KZN88203.1 - 0.032 13.8 8.5 0.1 12.2 5.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain EB1_binding PF05937.6 KZN88203.1 - 0.041 14.2 2.3 0.041 14.2 1.6 1.7 2 0 0 2 2 2 0 EB-1 Binding Domain zf-RING_6 PF14835.1 KZN88203.1 - 0.068 12.9 8.9 0.8 9.5 3.7 2.5 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 KZN88203.1 - 0.17 11.5 5.4 0.35 10.5 3.7 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 KZN88203.1 - 0.23 11.0 13.1 0.83 9.2 0.3 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DNA_ligase_ZBD PF03119.11 KZN88203.1 - 1 9.1 5.5 0.31 10.7 0.4 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-rbx1 PF12678.2 KZN88203.1 - 1.9 8.6 8.6 9.8 6.3 6.2 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger DNA_pol_A PF00476.15 KZN88204.1 - 1.6e-99 333.1 0.0 2.2e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1454 PF07305.7 KZN88204.1 - 0.069 12.2 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) CorA PF01544.13 KZN88205.1 - 3.6e-25 88.5 9.0 3.8e-18 65.5 0.7 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.14 KZN88206.1 - 1.2e-48 165.7 0.0 1.6e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 KZN88207.1 - 3.4e-68 229.6 0.0 4.5e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KZN88207.1 - 4.1e-22 78.1 0.0 1.1e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KZN88207.1 - 6.2e-14 51.6 0.0 1.9e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KZN88207.1 - 1.1e-06 28.4 11.4 2.4e-06 27.4 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN88207.1 - 6e-05 22.6 9.0 0.00011 21.8 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN88207.1 - 0.0021 17.8 10.4 0.0041 16.9 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN88207.1 - 0.0052 16.4 10.6 0.0099 15.5 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN88207.1 - 0.0067 16.0 11.4 0.014 15.0 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN88207.1 - 0.18 11.5 8.0 0.41 10.4 5.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KZN88207.1 - 0.92 9.4 10.7 1.9 8.4 7.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GTP_EFTU PF00009.22 KZN88209.1 - 2e-21 76.2 0.0 6.5e-21 74.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KZN88209.1 - 4.2e-14 52.5 0.0 8.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KZN88209.1 - 5.6e-07 29.5 2.4 2.7e-06 27.4 1.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KZN88209.1 - 0.0018 17.7 0.5 0.43 10.0 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KZN88209.1 - 0.1 13.1 0.5 1.2 9.6 0.3 2.6 2 1 0 2 2 2 0 Miro-like protein COG6 PF06419.6 KZN88209.1 - 0.22 9.6 0.0 0.33 9.0 0.0 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 LSM PF01423.17 KZN88210.1 - 2.9e-18 65.1 0.2 3.7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 KZN88210.1 - 0.39 10.3 1.7 5.6 6.6 0.0 2.6 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 KZN88211.1 - 1.6e-25 88.9 0.0 3.3e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 KZN88211.1 - 0.016 15.1 0.0 4.8 7.2 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family PIG-L PF02585.12 KZN88212.1 - 1.7e-29 102.9 0.0 3.4e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase LDB19 PF13002.2 KZN88213.1 - 1.5e-58 197.4 0.0 2.3e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KZN88213.1 - 2.3e-07 30.7 0.1 9.2e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 KZN88213.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) D-ser_dehydrat PF14031.1 KZN88214.1 - 3.6e-30 104.0 0.6 7.9e-30 102.9 0.1 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KZN88214.1 - 1.8e-13 50.5 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain CcmD PF04995.9 KZN88215.1 - 0.24 11.1 3.1 0.4 10.4 2.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FtsJ PF01728.14 KZN88216.1 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KZN88216.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AAA_16 PF13191.1 KZN88217.1 - 2.6e-12 47.1 0.4 1.7e-11 44.4 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KZN88217.1 - 3.8e-11 43.3 0.0 2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN88217.1 - 1.9e-10 40.9 0.0 4.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KZN88217.1 - 2.5e-06 27.1 0.0 6.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal KTI12 PF08433.5 KZN88217.1 - 0.00011 21.5 0.3 0.055 12.6 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KZN88217.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 NTPase PIF1 PF05970.9 KZN88217.1 - 0.0074 15.2 0.0 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase Arch_ATPase PF01637.13 KZN88217.1 - 0.0097 15.6 0.0 0.027 14.1 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase TIP49 PF06068.8 KZN88217.1 - 0.013 14.2 0.0 0.024 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 KZN88217.1 - 0.015 16.1 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KZN88217.1 - 0.02 13.6 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KZN88217.1 - 0.023 14.8 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KZN88217.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KZN88217.1 - 0.067 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thioredoxin_7 PF13899.1 KZN88218.1 - 6.1e-15 55.0 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KZN88218.1 - 3.9e-13 48.6 0.0 7.8e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KZN88218.1 - 2.1e-09 37.2 0.0 2.2e-08 34.0 0.0 2.3 3 0 0 3 3 3 1 UBX domain Thioredoxin_2 PF13098.1 KZN88218.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 KZN88218.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.20 KZN88219.1 - 1.3e-68 230.9 0.0 2.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88219.1 - 2.5e-49 167.7 0.0 5.3e-49 166.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN88219.1 - 1.3e-06 27.5 0.0 2.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Fungal_trans PF04082.13 KZN88220.1 - 3.6e-25 88.3 0.4 5.5e-25 87.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88220.1 - 5.1e-07 29.5 10.5 8.5e-07 28.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 KZN88221.1 - 5.4e-21 74.6 0.0 9.4e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KZN88221.1 - 7.5e-12 45.6 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KZN88221.1 - 2.2e-10 40.5 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.1 KZN88222.1 - 5.9e-13 49.1 0.0 6.5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN88222.1 - 5.6e-05 23.1 0.3 7.3e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Amidohydro_2 PF04909.9 KZN88223.1 - 1.3e-13 51.1 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase UxaC PF02614.9 KZN88223.1 - 0.044 12.4 0.5 0.062 11.8 0.3 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Peptidase_M19 PF01244.16 KZN88223.1 - 0.13 11.1 0.0 0.32 9.8 0.0 1.5 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.22 KZN88224.1 - 7.9e-15 54.7 0.5 1.9e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KZN88224.1 - 1e-11 44.8 0.0 4.4e-11 42.8 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KZN88224.1 - 6.8e-10 38.5 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease PF00324.16 KZN88225.1 - 1.3e-145 485.4 39.1 1.5e-145 485.2 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN88225.1 - 7.9e-39 133.3 38.3 1.1e-38 132.9 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 KZN88226.1 - 3.7e-19 68.0 0.0 4.2e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 KZN88227.1 - 1e-18 67.4 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.9 KZN88228.1 - 4.4e-44 150.5 6.1 5.5e-44 150.2 4.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KZN88228.1 - 4.7e-10 38.9 7.4 7.3e-10 38.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88228.1 - 4.9e-10 39.2 9.7 7.5e-10 38.6 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN88228.1 - 1.4e-09 37.6 10.0 2.2e-09 36.9 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN88228.1 - 2.2e-09 36.8 6.3 3.3e-09 36.2 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN88228.1 - 8.4e-08 31.8 6.8 1.3e-07 31.1 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KZN88228.1 - 1.1e-05 25.2 8.5 1.9e-05 24.4 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN88228.1 - 2e-05 24.1 2.7 2.4e-05 23.9 0.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KZN88228.1 - 0.00072 19.6 8.3 0.0017 18.3 5.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KZN88228.1 - 0.001 18.7 2.7 0.0019 17.9 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KZN88228.1 - 0.044 13.6 3.4 0.075 12.8 2.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 KZN88228.1 - 0.066 13.1 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 U-box domain DUF2851 PF11013.3 KZN88228.1 - 0.07 11.8 0.1 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) zf-RING_4 PF14570.1 KZN88228.1 - 0.094 12.3 7.5 0.18 11.4 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KZN88228.1 - 0.13 11.7 3.1 0.28 10.7 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 KZN88228.1 - 0.69 9.8 6.7 2.1 8.2 4.7 1.8 1 1 0 1 1 1 0 IBR domain FYVE PF01363.16 KZN88228.1 - 1.9 8.4 6.3 6.4 6.7 4.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger EXS PF03124.9 KZN88229.1 - 4.9e-94 315.1 13.5 5.7e-94 314.9 9.4 1.0 1 0 0 1 1 1 1 EXS family CMAS PF02353.15 KZN88230.1 - 9e-62 208.6 0.0 1.1e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KZN88230.1 - 8.8e-12 45.0 0.0 1.6e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN88230.1 - 1.9e-07 31.4 0.0 3.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88230.1 - 2.8e-05 24.6 0.0 5.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN88230.1 - 4.4e-05 23.8 0.0 8.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN88230.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN88230.1 - 0.00044 19.6 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KZN88230.1 - 0.0018 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KZN88230.1 - 0.0051 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 KZN88230.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KZN88230.1 - 0.031 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 KZN88230.1 - 0.055 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KZN88230.1 - 0.062 13.2 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tropomyosin_1 PF12718.2 KZN88232.1 - 2.7e-44 150.4 36.8 3.2e-44 150.2 25.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KZN88232.1 - 9.7e-10 37.9 35.7 0.00017 20.7 9.9 2.7 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 KZN88232.1 - 0.0025 17.6 5.4 0.0025 17.6 3.7 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 KZN88232.1 - 0.0058 16.9 33.5 2.9 8.2 7.2 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF904) CCDC155 PF14662.1 KZN88232.1 - 0.0077 15.8 34.6 0.064 12.8 13.4 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 MAD PF05557.8 KZN88232.1 - 0.011 13.8 24.6 0.015 13.4 17.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein IncA PF04156.9 KZN88232.1 - 0.012 15.2 34.8 0.63 9.6 17.7 2.2 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 KZN88232.1 - 0.012 14.7 31.3 0.15 11.2 15.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 KZN88232.1 - 0.014 14.9 29.2 0.032 13.7 12.0 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 KZN88232.1 - 0.055 13.2 20.3 0.26 11.0 5.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.4 KZN88232.1 - 0.056 12.3 28.5 0.14 11.0 15.9 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 KZN88232.1 - 0.068 12.6 37.0 0.28 10.7 10.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family KLRAQ PF10205.4 KZN88232.1 - 0.11 12.5 22.3 0.052 13.5 6.9 2.5 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein NABP PF07990.7 KZN88232.1 - 0.12 11.6 5.7 0.12 11.5 3.9 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ATG16 PF08614.6 KZN88232.1 - 0.12 12.1 30.5 1.2 8.8 10.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 KZN88232.1 - 0.13 12.6 28.1 0.43 10.9 7.8 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Mod_r PF07200.8 KZN88232.1 - 0.19 11.6 29.4 0.088 12.7 14.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 KZN88232.1 - 0.21 11.3 36.4 0.24 11.1 7.0 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KZN88232.1 - 0.25 11.2 33.6 5.7 6.8 10.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 KZN88232.1 - 0.3 9.4 27.1 0.72 8.1 7.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Striatin PF08232.7 KZN88232.1 - 0.36 11.1 25.3 0.55 10.5 12.5 2.2 1 1 1 2 2 2 0 Striatin family APG6 PF04111.7 KZN88232.1 - 0.43 9.5 35.0 0.83 8.6 9.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 KZN88232.1 - 0.43 10.5 34.2 0.18 11.7 10.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 KZN88232.1 - 0.48 10.1 28.8 4.5 7.0 14.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.1 KZN88232.1 - 0.94 9.9 27.5 1.5 9.3 1.9 3.6 1 1 2 3 3 2 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 KZN88232.1 - 1.1 8.4 7.7 1.5 7.9 4.8 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF724 PF05266.9 KZN88232.1 - 1.1 8.8 29.7 0.21 11.2 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMCO5 PF14992.1 KZN88232.1 - 1.7 7.7 29.2 0.8 8.7 2.0 2.0 1 1 1 2 2 2 0 TMCO5 family TMF_DNA_bd PF12329.3 KZN88232.1 - 1.8 8.4 38.4 0.49 10.2 2.8 3.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 KZN88232.1 - 2 8.2 13.6 7 6.4 0.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 KZN88232.1 - 2.6 7.6 26.6 1.8 8.2 1.4 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 SlyX PF04102.7 KZN88232.1 - 2.7 8.4 24.0 0.96 9.8 4.7 3.5 1 1 1 3 3 2 0 SlyX DUF745 PF05335.8 KZN88232.1 - 3 7.3 23.8 2.8 7.4 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4201 PF13870.1 KZN88232.1 - 3.3 7.0 29.3 1.6 8.1 15.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) BssS PF13991.1 KZN88232.1 - 3.4 7.4 5.8 0.79 9.4 0.2 2.4 2 1 0 2 2 2 0 BssS protein family AAA_13 PF13166.1 KZN88232.1 - 3.9 5.8 27.0 41 2.4 18.7 1.8 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.3 KZN88232.1 - 4 6.6 27.9 1.1 8.4 3.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 KZN88232.1 - 4.8 7.2 31.4 5.2 7.1 0.6 4.9 1 1 3 4 4 4 0 bZIP transcription factor DUF3251 PF11622.3 KZN88232.1 - 4.9 6.5 7.4 8.1 5.8 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3251) DUF641 PF04859.7 KZN88232.1 - 6.6 6.4 21.3 0.32 10.7 3.6 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.10 KZN88232.1 - 6.7 5.8 23.5 8.1 5.5 4.2 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit IFT46_B_C PF12317.3 KZN88232.1 - 7.6 5.8 9.8 4.5 6.5 5.0 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 KZN88232.1 - 9.9 4.7 29.4 5.4 5.5 7.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.10 KZN88232.1 - 10 6.0 36.3 2.8 7.8 1.7 5.1 1 1 4 5 5 5 0 Basic region leucine zipper Nop25 PF09805.4 KZN88233.1 - 6.1e-37 126.7 20.4 6.1e-37 126.7 14.1 2.9 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) zf-SAP30 PF13866.1 KZN88233.1 - 0.13 11.9 0.4 0.13 11.9 0.3 1.9 2 0 0 2 2 2 0 SAP30 zinc-finger DUF4604 PF15377.1 KZN88233.1 - 7.2 6.7 37.5 0.034 14.3 15.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) ATP-synt_S1 PF05827.7 KZN88234.1 - 2.3e-59 201.0 0.0 2.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.8 KZN88234.1 - 0.027 14.8 0.2 0.048 14.0 0.2 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cu_amine_oxid PF01179.15 KZN88235.1 - 6e-171 568.7 1.6 7.1e-171 568.4 1.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KZN88235.1 - 1.9e-06 27.8 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KZN88235.1 - 7.4e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.3 KZN88236.1 - 3.5e-51 173.9 0.1 5.4e-51 173.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KZN88237.1 - 1.1e-35 123.0 34.1 1.2e-35 122.8 23.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pex24p PF06398.6 KZN88238.1 - 2.9e-99 332.2 0.4 4.1e-99 331.7 0.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.8 KZN88239.1 - 8.5e-32 109.6 0.3 1e-31 109.3 0.2 1.0 1 0 0 1 1 1 1 Pam16 Closter_coat PF01785.12 KZN88239.1 - 0.0083 15.1 0.0 0.019 14.0 0.0 1.5 2 0 0 2 2 2 1 Closterovirus coat protein Aldo_ket_red PF00248.16 KZN88240.1 - 3.5e-66 222.9 0.0 4.5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S16 PF00886.14 KZN88240.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S16 PAP_assoc PF03828.14 KZN88241.1 - 1.7e-10 40.6 1.4 6.1e-10 38.9 0.4 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KZN88241.1 - 9.9e-10 38.6 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Bravo_FIGEY PF13882.1 KZN88241.1 - 0.24 12.3 0.1 0.24 12.3 0.0 2.7 3 0 0 3 3 3 0 Bravo-like intracellular region PRKCSH-like PF12999.2 KZN88243.1 - 2.2e-43 147.8 15.9 7.4e-27 94.0 1.0 3.4 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KZN88243.1 - 3.1e-33 114.4 8.0 1e-32 112.7 2.6 2.8 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KZN88243.1 - 1.6e-07 32.0 2.6 5.1e-07 30.4 1.8 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MRP-S25 PF13741.1 KZN88243.1 - 0.0014 18.1 0.7 0.0029 17.1 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Fib_alpha PF08702.5 KZN88243.1 - 0.0068 16.5 10.9 0.31 11.1 0.0 3.2 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family PRCC PF10253.4 KZN88243.1 - 0.16 12.6 12.2 0.58 10.8 5.2 2.7 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting V_ATPase_I PF01496.14 KZN88243.1 - 5.4 4.7 8.4 0.72 7.6 2.8 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Ldl_recept_a PF00057.13 KZN88243.1 - 7.1 6.6 13.2 0.69 9.8 1.2 3.1 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Rtf2 PF04641.7 KZN88244.1 - 6.6e-67 225.4 1.2 9.5e-67 224.9 0.8 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KZN88244.1 - 3.2e-09 36.1 0.4 0.0016 17.9 0.0 3.0 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KZN88244.1 - 1.9e-06 27.4 1.8 8.8e-06 25.3 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KZN88244.1 - 0.0025 17.5 0.1 0.0065 16.1 0.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN88244.1 - 0.02 14.6 0.3 0.12 12.2 0.0 2.3 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_3 PF13920.1 KZN88244.1 - 0.041 13.5 0.3 0.089 12.4 0.1 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88244.1 - 0.07 13.1 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L50 PF10501.4 KZN88245.1 - 8.7e-11 41.7 0.1 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S ArsA_ATPase PF02374.10 KZN88245.1 - 0.054 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase Thiolase_N PF00108.18 KZN88246.1 - 1.6e-77 260.0 0.2 2.3e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN88246.1 - 4.4e-44 148.8 1.0 1.1e-43 147.5 0.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KZN88246.1 - 0.17 11.5 1.0 7.7 6.2 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RNase_H PF00075.19 KZN88247.1 - 1.2e-06 28.9 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNase H UPF0254 PF06787.6 KZN88247.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) DAHP_synth_1 PF00793.15 KZN88249.1 - 2.8e-94 314.8 0.0 3.4e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 KZN88250.1 - 4e-18 64.7 0.4 4e-18 64.7 0.3 2.0 3 0 0 3 3 3 1 Cytochrome oxidase c assembly ECM11 PF15463.1 KZN88250.1 - 0.00033 20.9 1.5 0.00058 20.1 0.0 2.1 2 1 1 3 3 3 1 Extracellular mutant protein 11 DUF2458 PF10454.4 KZN88251.1 - 1e-43 148.8 0.0 1.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) PHA_synth_III_E PF09712.5 KZN88251.1 - 0.0064 15.9 0.2 0.0097 15.3 0.2 1.4 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) RIC3 PF15361.1 KZN88251.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.8 2 1 1 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.13 KZN88252.1 - 8.4e-14 51.0 0.4 8.4e-14 51.0 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CDO_I PF05995.7 KZN88253.1 - 5.9e-39 133.0 0.0 7.2e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KZN88253.1 - 0.0006 19.2 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) NAD_binding_1 PF00175.16 KZN88254.1 - 6.7e-26 90.9 0.0 1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN88254.1 - 1.8e-14 53.6 0.0 3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KZN88254.1 - 9.2e-07 28.8 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KZN88254.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain APH PF01636.18 KZN88255.1 - 3.3e-15 56.4 0.0 1.9e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN88255.1 - 0.0041 16.1 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase Arylsulfotran_2 PF14269.1 KZN88256.1 - 1.3e-42 145.9 0.9 2.1e-42 145.3 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN88256.1 - 1.1e-11 43.9 0.5 1.3e-10 40.4 0.3 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Hexokinase_2 PF03727.11 KZN88259.1 - 1.6e-37 129.0 0.0 2.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KZN88259.1 - 1.3e-31 109.5 0.0 1.8e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase ketoacyl-synt PF00109.21 KZN88260.1 - 2.7e-70 236.7 0.0 5.2e-70 235.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN88260.1 - 2.2e-66 224.4 0.1 5.5e-66 223.0 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 KZN88260.1 - 2.3e-61 206.6 0.1 1e-60 204.5 0.0 2.3 2 0 0 2 2 1 1 KR domain adh_short PF00106.20 KZN88260.1 - 1.8e-49 167.8 1.7 3.4e-49 166.9 0.0 2.5 3 0 0 3 3 2 1 short chain dehydrogenase PS-DH PF14765.1 KZN88260.1 - 3.1e-43 148.0 0.0 5.4e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KZN88260.1 - 1e-38 131.8 0.5 4.2e-38 129.8 0.1 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN88260.1 - 5.2e-18 64.8 0.0 1.9e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88260.1 - 1.8e-12 48.2 0.0 5.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN88260.1 - 2.1e-08 33.8 0.1 4.9e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KZN88260.1 - 7.2e-05 22.9 0.6 0.00018 21.7 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.1 KZN88260.1 - 0.00017 21.4 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KZN88260.1 - 0.0057 16.6 1.7 2.3 8.1 0.1 3.1 3 0 0 3 3 2 2 NADH(P)-binding Thiolase_N PF00108.18 KZN88260.1 - 0.0094 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 KZN88260.1 - 0.013 15.5 0.1 0.079 13.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KZN88260.1 - 0.036 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.5 KZN88260.1 - 0.058 13.0 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF915 PF06028.6 KZN88260.1 - 0.49 9.4 0.0 0.92 8.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 KZN88261.1 - 2.2e-19 69.7 0.0 5.3e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KZN88261.1 - 0.00038 20.2 0.0 0.00079 19.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADK PF00406.17 KZN88263.1 - 1.2e-42 145.3 0.0 1.6e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 KZN88263.1 - 3.7e-08 33.3 0.0 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN88263.1 - 9e-08 32.9 0.0 1.4e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN88263.1 - 1e-07 32.3 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KZN88263.1 - 9.7e-07 28.3 0.0 0.035 13.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 KZN88263.1 - 0.1 11.6 0.0 0.53 9.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin PCI PF01399.22 KZN88264.1 - 6e-12 45.7 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain Herpes_capsid PF06112.6 KZN88265.1 - 8.9 6.3 11.4 14 5.6 7.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein 4HBT PF03061.17 KZN88266.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KZN88267.1 - 9.8e-59 199.1 1.6 1.1e-58 198.9 1.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily RTA1 PF04479.8 KZN88268.1 - 4.3e-38 131.0 12.4 4.3e-38 131.0 8.6 1.4 1 1 0 1 1 1 1 RTA1 like protein Tetraspannin PF00335.15 KZN88268.1 - 1.7 7.8 16.5 0.012 14.9 2.9 2.4 1 1 1 2 2 2 0 Tetraspanin family DUF2976 PF11190.3 KZN88268.1 - 2.9 7.4 10.9 6.6 6.3 0.4 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) DUF3098 PF11297.3 KZN88268.1 - 6 6.6 10.4 0.099 12.3 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Glyco_transf_20 PF00982.16 KZN88269.1 - 1.6e-159 531.4 0.0 2.5e-159 530.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KZN88269.1 - 4.6e-36 123.9 0.1 7.1e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 KZN88269.1 - 0.035 13.6 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Stk19 PF10494.4 KZN88270.1 - 2.3e-79 266.3 0.0 2.8e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 PTR PF12789.2 KZN88270.1 - 0.099 12.5 0.0 0.45 10.3 0.0 2.0 1 1 1 2 2 2 0 Phage tail repeat like DUF3074 PF11274.3 KZN88271.1 - 2.4e-32 112.0 0.0 3.4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) NHS PF15273.1 KZN88271.1 - 0.042 12.4 1.1 0.076 11.6 0.8 1.3 1 0 0 1 1 1 0 NHS-like zf-H2C2_2 PF13465.1 KZN88274.1 - 1e-13 50.8 16.7 1.4e-07 31.4 0.8 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KZN88274.1 - 1.7e-07 31.1 34.0 0.0009 19.4 3.1 4.1 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN88274.1 - 6.5e-05 22.9 33.7 0.0035 17.5 3.1 4.4 5 0 0 5 5 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN88274.1 - 0.00054 20.0 8.0 0.14 12.3 1.1 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN88274.1 - 0.012 15.5 11.4 0.05 13.5 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 KZN88274.1 - 0.015 15.4 9.5 0.049 13.7 3.8 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KZN88274.1 - 0.023 14.2 0.2 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-CHCC PF10276.4 KZN88274.1 - 0.031 14.1 3.8 5.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-RING_3 PF14369.1 KZN88274.1 - 0.29 11.1 4.7 17 5.5 0.1 3.4 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 KZN88274.1 - 0.32 10.8 7.0 5.2 6.9 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KZN88274.1 - 0.52 10.3 9.3 6.2 6.8 2.3 3.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-CHY PF05495.7 KZN88274.1 - 0.66 10.1 6.1 1.6 8.9 4.2 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 KZN88274.1 - 0.76 9.5 8.8 0.042 13.5 1.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.7 KZN88274.1 - 1.1 9.0 4.1 2 8.2 1.5 2.1 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.14 KZN88274.1 - 2.1 8.0 3.8 6 6.5 2.5 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 KZN88274.1 - 4.7 7.1 10.8 3 7.8 2.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF202 PF02656.10 KZN88275.1 - 0.54 10.5 7.2 6.3 7.0 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Tetraspannin PF00335.15 KZN88275.1 - 4.1 6.6 9.7 16 4.7 6.9 1.8 1 1 0 1 1 1 0 Tetraspanin family FixQ PF05545.6 KZN88275.1 - 5.9 6.6 11.0 2.2 7.9 0.3 3.7 3 1 1 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Cnd2 PF05786.9 KZN88276.1 - 9.1e-265 880.7 3.1 1.2e-264 880.3 2.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 eIF-3c_N PF05470.7 KZN88276.1 - 1 7.3 3.7 1.8 6.5 2.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Na_Ca_ex PF01699.19 KZN88277.1 - 8.2e-47 158.3 30.1 2.6e-24 85.4 8.0 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Fungal_trans PF04082.13 KZN88278.1 - 2.9e-15 55.8 0.6 5.7e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88278.1 - 3e-07 30.2 11.9 5.3e-07 29.4 6.3 2.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KZN88279.1 - 1.2e-23 83.7 0.3 1.8e-22 79.8 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN88279.1 - 3.7e-07 29.3 0.5 3.8e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN88279.1 - 1.3e-05 25.0 0.1 3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN88279.1 - 2.5e-05 24.4 0.1 0.00012 22.2 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN88279.1 - 0.00078 19.8 0.1 0.002 18.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN88279.1 - 0.0045 16.7 0.3 0.062 13.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.5 KZN88279.1 - 0.031 13.0 0.0 0.79 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 KZN88279.1 - 0.062 11.9 0.6 0.71 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 KZN88279.1 - 0.095 11.7 0.9 2.5 7.0 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase ketoacyl-synt PF00109.21 KZN88280.1 - 9e-69 231.7 0.1 2.1e-68 230.5 0.0 1.7 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KZN88280.1 - 1.6e-33 115.0 0.0 3.1e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KZN88280.1 - 2.2e-30 106.0 0.0 3.6e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KZN88280.1 - 1.2e-23 83.3 0.0 2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KZN88280.1 - 1.8e-15 57.2 0.0 5.4e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88280.1 - 1.1e-10 41.2 0.0 2.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN88280.1 - 1.8e-10 40.7 0.0 5.3e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KZN88280.1 - 2.7e-08 33.9 0.4 6.8e-08 32.6 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KZN88280.1 - 5.6e-07 29.9 0.0 2.1e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN88280.1 - 2.4e-05 24.6 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88280.1 - 0.00011 22.7 0.0 0.00059 20.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KZN88280.1 - 0.00043 19.7 0.0 0.0012 18.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NodS PF05401.6 KZN88280.1 - 0.0012 18.3 0.0 0.0055 16.1 0.0 2.1 3 0 0 3 3 2 1 Nodulation protein S (NodS) adh_short PF00106.20 KZN88280.1 - 0.0049 16.7 0.2 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RrnaAD PF00398.15 KZN88280.1 - 0.018 14.0 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KZN88280.1 - 0.03 14.3 0.0 0.088 12.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.18 KZN88280.1 - 0.032 13.2 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 KZN88280.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polysacc_synt_2 PF02719.10 KZN88280.1 - 0.82 8.5 0.0 1.7 7.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.21 KZN88281.1 - 1.3e-71 241.0 0.5 1.3e-71 241.0 0.3 2.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN88281.1 - 2.6e-56 190.1 0.4 9.1e-56 188.3 0.1 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KZN88281.1 - 4.3e-52 177.1 0.1 7.4e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN88281.1 - 4.5e-47 160.9 2.5 5.6e-47 160.6 0.4 2.1 3 0 0 3 3 3 1 Acyl transferase domain adh_short PF00106.20 KZN88281.1 - 9.3e-46 155.7 0.2 5.4e-45 153.3 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN88281.1 - 2.6e-39 133.7 0.3 1.1e-38 131.6 0.1 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN88281.1 - 2.4e-16 59.4 0.1 1.1e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KZN88281.1 - 1.2e-09 38.5 0.0 2.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN88281.1 - 2.2e-09 38.2 0.0 9.8e-09 36.1 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KZN88281.1 - 9.4e-08 31.9 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88281.1 - 3.1e-07 30.9 0.0 1.5e-06 28.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 KZN88281.1 - 1.5e-06 27.4 0.1 3.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 KZN88281.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KZN88281.1 - 0.00012 22.2 0.3 0.00032 20.8 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KZN88281.1 - 0.00042 20.7 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain YjeF_N PF03853.10 KZN88281.1 - 0.011 15.3 1.9 0.39 10.3 0.1 3.4 3 0 0 3 3 3 0 YjeF-related protein N-terminus Methyltransf_26 PF13659.1 KZN88281.1 - 0.014 15.3 0.0 0.048 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 KZN88281.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KZN88281.1 - 0.058 12.9 0.7 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LEM PF03020.10 KZN88281.1 - 0.15 11.5 0.0 0.45 10.0 0.0 1.8 1 0 0 1 1 1 0 LEM domain Fungal_trans PF04082.13 KZN88282.1 - 1e-17 63.8 1.0 1e-17 63.8 0.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KZN88283.1 - 3.2e-31 108.3 31.9 3.2e-31 108.3 22.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 KZN88284.1 - 1.7e-25 89.0 1.4 3.4e-25 88.1 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN88284.1 - 4.5e-13 48.8 0.3 1.9e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.9 KZN88284.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase EF-hand_4 PF12763.2 KZN88285.1 - 6.2e-27 93.3 0.0 1.5e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 KZN88285.1 - 4.6e-10 38.7 1.1 1e-09 37.6 0.8 1.6 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 KZN88285.1 - 5.6e-08 32.7 154.2 0.00042 20.3 23.7 7.6 4 2 3 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KZN88285.1 - 4.6e-06 26.6 0.1 0.00042 20.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KZN88285.1 - 0.017 14.3 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KZN88285.1 - 0.14 12.1 0.0 43 4.3 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain RNA_pol_L_2 PF13656.1 KZN88286.1 - 6.8e-23 79.8 0.0 1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KZN88286.1 - 2.2e-12 45.8 0.0 3.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PBP1_TM PF14812.1 KZN88287.1 - 0.52 10.6 16.4 4.7 7.5 0.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.12 KZN88287.1 - 9.5 4.9 4.5 25 3.5 3.1 1.6 1 0 0 1 1 1 0 Presenilin PMT PF02366.13 KZN88288.1 - 1.6e-82 276.5 18.1 2.7e-82 275.8 12.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KZN88288.1 - 2.4e-22 79.4 0.5 4.5e-22 78.5 0.2 1.5 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KZN88288.1 - 0.0015 18.4 13.2 0.0015 18.4 9.1 4.4 5 1 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Erf4 PF10256.4 KZN88289.1 - 0.021 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 KZN88289.1 - 0.045 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) MFS_1 PF07690.11 KZN88291.1 - 2.1e-30 105.6 33.4 2.1e-30 105.6 23.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88291.1 - 3.4e-06 25.9 27.3 5.3e-06 25.2 18.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 KZN88292.1 - 4.2 7.5 8.8 5.5 7.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) WD40 PF00400.27 KZN88293.1 - 7.2e-14 51.0 9.6 5.7e-06 26.0 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 KZN88294.1 - 5.9e-25 87.0 0.8 6.4e-25 86.9 0.6 1.0 1 0 0 1 1 1 1 ATP synthase E chain FCH PF00611.18 KZN88294.1 - 0.031 14.4 1.0 0.038 14.1 0.7 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Chordopox_A13L PF05961.6 KZN88294.1 - 0.23 11.4 1.6 0.62 10.0 0.4 1.9 1 1 1 2 2 2 0 Chordopoxvirus A13L protein PCI_Csn8 PF10075.4 KZN88295.1 - 7.5e-30 103.5 0.1 1.1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KZN88295.1 - 2.5e-05 23.9 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family STT3 PF02516.9 KZN88296.1 - 1.8e-132 442.7 38.9 9.6e-128 427.1 25.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Coiled-coil_56 PF09813.4 KZN88297.1 - 3.9e-05 23.5 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 KZN88298.1 - 1.7e-73 246.9 0.0 3.3e-73 246.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) p450 PF00067.17 KZN88299.1 - 1.8e-69 234.4 0.0 2.2e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 KZN88300.1 - 5.3e-31 107.4 0.0 9.1e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN88300.1 - 6.8e-27 93.5 0.0 1.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KZN88300.1 - 1.6e-22 79.0 0.1 4.2e-22 77.7 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KZN88300.1 - 2.8e-05 24.0 0.0 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KZN88300.1 - 0.011 15.7 0.0 0.24 11.3 0.0 2.3 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.13 KZN88301.1 - 1.5e-32 112.6 0.0 2.1e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN88301.1 - 7e-09 35.9 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KZN88301.1 - 2.2e-06 27.4 0.0 3.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KZN88301.1 - 0.00074 19.3 0.0 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.12 KZN88301.1 - 0.036 14.3 1.5 7.9 6.8 0.0 4.7 5 1 0 5 5 5 0 Low-density lipoprotein receptor repeat class B UDPG_MGDP_dh_N PF03721.9 KZN88301.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 KZN88302.1 - 2.6e-13 49.4 0.8 2.6e-13 49.4 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88302.1 - 3.5e-08 33.2 10.0 8.6e-08 31.9 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN88303.1 - 1.3e-43 149.1 38.2 1.3e-43 149.1 26.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88303.1 - 4.8e-09 35.3 14.5 4.8e-09 35.3 10.1 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter OAD_gamma PF04277.8 KZN88303.1 - 7.2 7.0 6.2 12 6.3 0.1 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Fungal_trans PF04082.13 KZN88304.1 - 4.9e-28 97.7 1.6 7.9e-28 97.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sds3 PF08598.6 KZN88305.1 - 1.1e-27 96.9 2.3 1.1e-27 96.9 1.6 3.3 3 1 0 3 3 3 1 Sds3-like Ku_PK_bind PF08785.6 KZN88305.1 - 0.047 13.5 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like RRM_1 PF00076.17 KZN88306.1 - 4.1e-05 23.1 0.0 0.033 13.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN88306.1 - 0.00029 20.6 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN88306.1 - 0.014 15.3 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 KZN88308.1 - 4e-29 102.1 0.0 6.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN88308.1 - 2.6e-06 27.4 0.0 5.9e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN88308.1 - 1.5e-05 24.7 0.0 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN88308.1 - 0.00029 19.8 0.0 0.0043 16.0 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KZN88308.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GPI-anchored PF10342.4 KZN88310.1 - 1.2e-20 73.8 1.7 1.2e-20 73.8 1.2 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KZN88310.1 - 1.3e-06 28.0 2.2 1.3e-06 28.0 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) DUF605 PF04652.11 KZN88310.1 - 0.23 10.8 15.1 0.27 10.6 10.4 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 KZN88310.1 - 0.57 8.7 27.9 0.72 8.4 19.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.8 KZN88310.1 - 0.86 8.7 18.7 1.2 8.3 13.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 KZN88310.1 - 1 9.1 10.1 1.3 8.8 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KZN88310.1 - 3 6.0 24.1 3.5 5.7 16.7 1.0 1 0 0 1 1 1 0 Transmembrane protein NUFIP1 PF10453.4 KZN88311.1 - 9.7e-17 60.2 1.4 9.7e-17 60.2 1.0 4.4 4 1 1 5 5 5 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KZN88311.1 - 1.3e-08 34.3 4.8 2.3e-08 33.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.7 KZN88312.1 - 8e-37 126.1 0.2 1.1e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KZN88312.1 - 1.5e-14 53.8 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 KZN88313.1 - 1e-139 465.1 0.1 1.1e-139 465.0 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KZN88313.1 - 2.4e-09 36.6 0.1 3.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KZN88313.1 - 6.4e-08 32.0 0.1 1.3e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KZN88313.1 - 3.3e-07 29.3 0.6 6.8e-07 28.3 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KZN88313.1 - 5.2e-06 25.8 0.1 9.9e-06 24.8 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Methyltransf_16 PF10294.4 KZN88314.1 - 0.0038 16.6 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Filament PF00038.16 KZN88316.1 - 0.0034 16.9 69.0 0.011 15.2 40.1 3.2 1 1 2 3 3 3 2 Intermediate filament protein DUF3584 PF12128.3 KZN88316.1 - 0.088 10.1 71.2 0.034 11.4 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 KZN88316.1 - 0.46 10.0 78.4 1.4 8.4 19.0 3.6 1 1 2 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 KZN88316.1 - 0.5 9.4 19.4 0.57 9.3 3.1 3.6 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Cellulase PF00150.13 KZN88317.1 - 1.4e-15 57.2 2.3 1.9e-15 56.8 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KZN88317.1 - 0.00035 19.8 1.2 0.03 13.4 0.1 2.5 3 0 0 3 3 3 2 Beta-galactosidase Cellulase-like PF12876.2 KZN88317.1 - 0.0025 18.1 0.0 0.0058 17.0 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 KZN88317.1 - 0.0032 16.5 0.3 0.027 13.5 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 10 Glyco_hydro_2_C PF02836.12 KZN88317.1 - 0.012 14.5 0.3 0.024 13.5 0.2 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AP_endonuc_2 PF01261.19 KZN88317.1 - 0.045 13.0 0.0 0.073 12.3 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Acyltransferase PF01553.16 KZN88319.1 - 1.5e-16 60.0 0.0 3.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.10 KZN88320.1 - 1.2e-79 266.9 0.0 7.8e-79 264.3 0.0 1.9 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 KZN88321.1 - 3e-41 140.7 0.1 4.6e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KZN88321.1 - 8.8e-19 66.8 0.0 1.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KZN88321.1 - 1.7e-18 66.2 0.0 4.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN88321.1 - 0.00015 21.6 0.9 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAM176 PF14851.1 KZN88321.1 - 0.021 14.4 3.2 0.15 11.7 0.3 2.8 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.5 KZN88321.1 - 9 6.6 15.2 2.1 8.6 4.4 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain WD40 PF00400.27 KZN88322.1 - 1.5e-20 72.2 11.3 0.00062 19.5 0.2 7.7 8 1 0 8 8 8 5 WD domain, G-beta repeat DYW_deaminase PF14432.1 KZN88323.1 - 1.4e-18 66.9 0.0 4.9e-18 65.2 0.0 1.9 2 1 0 2 2 2 1 DYW family of nucleic acid deaminases Ank_2 PF12796.2 KZN88323.1 - 2.2e-16 59.9 0.1 4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN88323.1 - 1.4e-15 56.9 1.9 3.1e-09 36.7 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN88323.1 - 1.8e-15 55.8 0.2 2.4e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KZN88323.1 - 5.4e-11 41.6 0.0 0.00048 20.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KZN88323.1 - 8.2e-10 38.9 0.5 2.3e-07 31.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) IncA PF04156.9 KZN88323.1 - 3.4 7.2 5.5 6.3 6.3 3.8 1.4 1 0 0 1 1 1 0 IncA protein Fungal_trans_2 PF11951.3 KZN88324.1 - 4.8e-13 48.4 0.1 1.3e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88324.1 - 3.8e-05 23.5 10.9 6.9e-05 22.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN88325.1 - 6.4e-39 133.6 58.2 1.7e-31 109.2 23.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88325.1 - 1e-08 34.2 19.3 1e-08 34.2 13.4 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KZN88325.1 - 1.4e-05 23.5 21.5 2.2e-05 22.8 14.9 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2048 PF09752.4 KZN88325.1 - 0.089 11.6 0.3 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF3309 PF11752.3 KZN88325.1 - 8.1 6.3 14.9 2.3 8.0 5.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) GATase PF00117.23 KZN88326.1 - 1.3e-12 47.6 0.0 1.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN88326.1 - 0.0042 16.5 0.1 0.045 13.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KZN88326.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain OTU PF02338.14 KZN88327.1 - 1.2e-14 54.9 0.3 3.8e-14 53.3 0.2 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KZN88327.1 - 0.0009 18.6 0.1 0.0025 17.2 0.0 1.7 2 0 0 2 2 2 1 CUE domain Peptidase_C65 PF10275.4 KZN88327.1 - 0.0061 15.9 0.1 3.5 6.8 0.0 2.3 1 1 0 2 2 2 2 Peptidase C65 Otubain UBA_4 PF14555.1 KZN88327.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain DAO PF01266.19 KZN88328.1 - 2.1e-17 63.1 0.0 2.5e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase TFIIA_gamma_N PF02268.11 KZN88329.1 - 0.11 12.1 0.2 5.9 6.5 0.1 3.0 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain MFS_1 PF07690.11 KZN88330.1 - 4.8e-39 134.0 37.6 4.7e-34 117.6 19.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN88330.1 - 0.0012 17.2 26.8 0.0054 15.1 6.0 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4131 PF13567.1 KZN88330.1 - 0.11 11.8 6.9 5.1 6.4 2.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2613 PF11021.3 KZN88330.1 - 0.16 11.7 7.5 1.3 8.7 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) DUF4418 PF14387.1 KZN88330.1 - 3 7.5 9.5 0.67 9.7 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) COPI_assoc PF08507.5 KZN88331.1 - 2.9e-43 146.8 5.8 3.2e-43 146.7 4.0 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.8 KZN88331.1 - 0.21 11.1 1.6 0.36 10.4 1.1 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Bax1-I PF01027.15 KZN88331.1 - 4 6.9 13.0 6.6 6.2 9.0 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2892 PF11127.3 KZN88331.1 - 7.9 6.3 15.9 0.81 9.5 3.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2892) Cg6151-P PF10233.4 KZN88331.1 - 9.6 6.2 8.4 31 4.5 3.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein CG6151-P GATA PF00320.22 KZN88332.1 - 2.8e-30 103.3 17.9 7.8e-16 57.1 4.3 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KZN88332.1 - 1.1e-05 24.6 1.9 0.0063 15.8 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 KZN88332.1 - 9.1e-05 22.0 2.6 0.12 12.0 0.2 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 KZN88332.1 - 0.0008 18.5 7.3 0.074 12.2 0.3 3.0 2 1 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 KZN88332.1 - 0.0064 16.2 5.4 0.073 12.8 0.3 2.5 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 KZN88332.1 - 0.054 13.4 2.7 1.6 8.7 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KZN88332.1 - 0.07 12.7 4.0 2.3 7.9 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_S27e PF01667.12 KZN88332.1 - 0.085 12.4 1.4 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 ArfGap PF01412.13 KZN88332.1 - 0.27 11.0 4.3 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf HypA PF01155.14 KZN88332.1 - 2 8.1 3.5 6.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PGA_cap PF09587.5 KZN88333.1 - 8e-58 195.7 0.0 1.2e-57 195.1 0.0 1.3 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap ABC2_membrane PF01061.19 KZN88334.1 - 3.6e-88 294.2 44.6 1.6e-47 161.3 11.0 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KZN88334.1 - 1.6e-40 138.6 0.0 8.3e-19 68.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN88334.1 - 5.1e-28 96.7 0.0 1.5e-24 85.5 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KZN88334.1 - 2.4e-14 53.1 26.7 4.5e-08 32.5 6.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KZN88334.1 - 1.8e-10 40.7 0.1 5.6e-10 39.1 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KZN88334.1 - 1.6e-05 24.1 0.1 0.0038 16.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KZN88334.1 - 6.3e-05 23.0 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KZN88334.1 - 7.5e-05 22.2 0.1 0.016 14.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KZN88334.1 - 0.00015 21.9 0.1 0.14 12.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 KZN88334.1 - 0.00024 20.6 0.9 0.4 10.0 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KZN88334.1 - 0.00028 20.7 0.0 1 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN88334.1 - 0.00091 18.7 0.5 0.077 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN88334.1 - 0.0015 18.5 0.5 0.28 11.1 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KZN88334.1 - 0.0024 17.8 0.8 0.36 10.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN88334.1 - 0.0043 17.3 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KZN88334.1 - 0.022 15.5 0.0 0.8 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN88334.1 - 0.025 14.3 0.7 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 KZN88334.1 - 0.025 14.2 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KZN88334.1 - 0.025 14.2 0.4 3.4 7.3 0.2 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 KZN88334.1 - 0.025 14.0 0.4 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KZN88334.1 - 0.032 14.2 0.0 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 KZN88334.1 - 0.072 12.3 0.0 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 KZN88334.1 - 0.23 11.2 0.1 1 9.1 0.0 2.1 3 0 0 3 3 3 0 Dynamin family bZIP_1 PF00170.16 KZN88335.1 - 1.8e-05 24.5 1.0 4.2e-05 23.4 0.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN88335.1 - 0.032 14.0 1.7 0.061 13.1 1.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Glutaredoxin2_C PF04399.8 KZN88335.1 - 0.051 13.1 0.1 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CinA PF02464.12 KZN88335.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Competence-damaged protein Tropomyosin_1 PF12718.2 KZN88335.1 - 0.076 12.8 0.6 0.13 12.0 0.4 1.3 1 0 0 1 1 1 0 Tropomyosin like adh_short PF00106.20 KZN88336.1 - 4.5e-22 78.7 0.1 6.3e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88336.1 - 4e-11 43.1 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KZN88336.1 - 2e-06 27.1 0.0 6.2e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KZN88336.1 - 0.00023 21.2 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KZN88336.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 KZN88336.1 - 0.061 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA VWA_2 PF13519.1 KZN88336.1 - 0.076 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain TrkA_N PF02254.13 KZN88336.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Tautomerase_3 PF14832.1 KZN88337.1 - 2.4e-55 186.2 0.1 2.7e-55 186.0 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme MFS_1 PF07690.11 KZN88339.1 - 2.3e-25 89.0 56.1 3.5e-25 88.4 36.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Nitroreductase PF00881.19 KZN88340.1 - 1.8e-11 44.1 0.0 2.3e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family p450 PF00067.17 KZN88343.1 - 1.2e-46 159.2 0.0 1.5e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KZN88344.1 - 1.7e-20 72.9 5.3 1.7e-20 72.9 1.9 2.2 3 0 0 3 3 3 1 FAD binding domain MFS_3 PF05977.8 KZN88344.1 - 0.043 11.9 0.0 0.067 11.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.11 KZN88346.1 - 1.4e-34 119.3 34.2 5e-34 117.5 24.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 KZN88346.1 - 0.0038 17.5 0.2 0.013 15.8 0.2 1.9 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2762 PF10960.3 KZN88346.1 - 0.18 11.5 0.1 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) NfeD PF01957.13 KZN88346.1 - 2.8 8.0 19.4 1.9 8.6 1.2 4.2 2 2 3 5 5 5 0 NfeD-like C-terminal, partner-binding Prominin PF05478.6 KZN88347.1 - 3.4 5.0 4.6 0.53 7.7 0.1 1.7 2 0 0 2 2 2 0 Prominin FAD_binding_3 PF01494.14 KZN88348.1 - 4.9e-16 58.7 0.2 1.8e-10 40.4 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN88348.1 - 3.4e-07 30.1 0.2 9.8e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN88348.1 - 0.00022 21.5 0.0 0.055 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN88348.1 - 0.00024 20.1 0.0 0.007 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN88348.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KZN88348.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN88348.1 - 0.075 11.9 0.2 0.38 9.6 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN88348.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1654 PF07867.6 KZN88348.1 - 0.13 11.6 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) NAD_binding_9 PF13454.1 KZN88348.1 - 0.15 11.8 0.5 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Zn_clus PF00172.13 KZN88349.1 - 1.5e-09 37.5 15.4 3.1e-09 36.5 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN88350.1 - 9.1e-36 123.2 32.0 4.3e-35 121.0 23.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.7 KZN88350.1 - 0.24 11.1 0.0 0.24 11.1 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function, DUF485 OPT PF03169.10 KZN88351.1 - 9.9e-169 562.7 45.2 1.5e-168 562.0 31.3 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.20 KZN88354.1 - 1.7e-33 115.8 0.0 2.9e-33 115.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88354.1 - 1e-14 54.9 0.1 1.2e-14 54.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88354.1 - 1.5e-12 47.5 0.0 2.6e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KZN88354.1 - 0.0056 15.6 0.4 0.011 14.6 0.3 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KZN88354.1 - 0.023 14.4 0.5 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KZN88354.1 - 0.034 13.5 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lin0512_fam PF09585.5 KZN88354.1 - 0.046 13.2 0.4 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) DUF258 PF03193.11 KZN88354.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MIT PF04212.13 KZN88356.1 - 0.00084 19.1 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 KZN88356.1 - 0.025 14.3 0.1 0.12 12.2 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat Ras PF00071.17 KZN88357.1 - 1.6e-58 196.6 0.2 1.8e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN88357.1 - 6.1e-18 65.4 0.0 8.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN88357.1 - 1.5e-08 34.0 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN88357.1 - 1.1e-07 31.5 0.1 5e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KZN88357.1 - 0.00086 18.6 0.0 0.0014 17.9 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KZN88357.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 KZN88357.1 - 0.051 12.9 0.7 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 KZN88357.1 - 0.061 12.5 0.1 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 KZN88357.1 - 0.066 12.6 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 KZN88357.1 - 0.2 11.1 2.4 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.19 KZN88358.1 - 2e-36 124.5 0.0 3.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 KZN88359.1 - 5.8e-12 45.6 0.0 6.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2732 PF10809.3 KZN88359.1 - 0.026 14.0 0.3 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) DUF4276 PF14103.1 KZN88360.1 - 0.099 12.4 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) 2OG-FeII_Oxy PF03171.15 KZN88361.1 - 3.6e-14 52.8 0.0 6.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KZN88361.1 - 2.3e-11 44.2 0.0 3.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 KZN88362.1 - 7.5e-30 102.4 0.2 1.2e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 tRNA_int_endo PF01974.12 KZN88363.1 - 2e-15 56.3 0.0 4.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Helicase_C PF00271.26 KZN88363.1 - 0.1 12.4 0.1 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Totivirus_coat PF05518.6 KZN88363.1 - 0.55 7.9 4.3 0.68 7.6 3.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein PAXNEB PF05625.6 KZN88365.1 - 1.8e-127 425.1 0.0 2e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 KZN88366.1 - 2.2e-39 134.7 0.0 2.5e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Proteasom_Rpn13 PF04683.8 KZN88366.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor NUDIX PF00293.23 KZN88367.1 - 9.5e-09 35.0 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 KZN88368.1 - 1.3e-59 201.1 0.0 1.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MHYT PF03707.11 KZN88369.1 - 1.2e-10 41.3 22.0 5e-06 26.5 0.6 4.4 4 1 0 4 4 4 2 Bacterial signalling protein N terminal repeat UBA PF00627.26 KZN88369.1 - 0.082 12.7 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 UBA/TS-N domain ABC2_membrane_5 PF13346.1 KZN88369.1 - 9.4 5.4 8.9 4.6 6.4 2.5 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein Thioredoxin PF00085.15 KZN88370.1 - 7.5e-31 105.8 0.1 8.1e-31 105.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KZN88370.1 - 5.4e-08 32.8 0.0 7.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KZN88370.1 - 8.5e-07 29.1 0.1 1.1e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KZN88370.1 - 5.8e-06 26.2 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KZN88370.1 - 9e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KZN88370.1 - 2.6e-05 23.7 0.0 3.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KZN88370.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.4 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 KZN88370.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 1 1 2 2 2 0 Glutaredoxin Cpl-7 PF08230.6 KZN88370.1 - 0.027 14.2 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain DSBA PF01323.15 KZN88370.1 - 0.049 13.1 0.0 1 8.8 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain IF-2B PF01008.12 KZN88373.1 - 2.4e-49 167.8 0.0 2.9e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.9 KZN88374.1 - 2.3e-45 154.1 0.2 2.3e-45 154.1 0.1 2.1 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 KZN88374.1 - 8.4 5.4 11.5 12 4.9 0.2 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Glyco_trans_4_4 PF13579.1 KZN88375.1 - 0.13 12.3 2.4 0.15 12.1 0.4 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Adaptin_N PF01602.15 KZN88376.1 - 5.5e-100 335.1 0.0 1.2e-99 334.0 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KZN88376.1 - 8.9e-11 41.9 0.0 0.00016 21.8 0.0 4.6 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KZN88376.1 - 1.5e-09 37.1 0.3 0.068 13.2 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.2 KZN88376.1 - 0.00073 19.4 0.3 0.056 13.4 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 KZN88376.1 - 0.0017 18.8 1.7 3.7 8.1 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Amidohydro_1 PF01979.15 KZN88377.1 - 1.6e-36 126.6 0.3 2e-36 126.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KZN88377.1 - 4.3e-16 59.7 0.1 2.2e-13 50.8 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KZN88377.1 - 3.9e-14 52.2 0.0 2.4e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN88377.1 - 1.3e-13 51.0 1.9 3.3e-12 46.3 0.1 2.4 1 1 1 2 2 2 2 Amidohydrolase family Metallophos PF00149.23 KZN88378.1 - 7.4e-41 139.7 0.4 9.6e-41 139.3 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KZN88379.1 - 1.1e-59 201.2 0.6 1.2e-59 201.1 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 KZN88380.1 - 0.00075 19.0 3.0 0.046 13.3 0.0 3.2 2 1 1 3 3 3 2 KilA-N domain FimP PF09766.4 KZN88380.1 - 0.41 9.6 18.2 0.41 9.6 2.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF940 PF06082.6 KZN88380.1 - 3.7 5.9 10.2 6.3 5.2 7.0 1.4 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Clp1 PF06807.9 KZN88381.1 - 1.6e-17 63.9 0.0 6.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KZN88381.1 - 0.00015 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KZN88381.1 - 0.00018 21.4 0.0 0.00068 19.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KZN88381.1 - 0.00018 21.1 0.0 0.0018 17.8 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.17 KZN88381.1 - 0.022 14.1 0.0 7 6.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_35 PF14516.1 KZN88381.1 - 0.025 13.2 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KZN88381.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KZN88381.1 - 0.061 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 KZN88381.1 - 0.14 11.3 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.5 KZN88381.1 - 0.18 11.0 0.0 0.44 9.7 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gly_transf_sug PF04488.10 KZN88382.1 - 1.9e-13 50.6 0.0 3.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.17 KZN88383.1 - 3.8e-41 141.0 34.6 4.7e-41 140.7 24.0 1.1 1 0 0 1 1 1 1 Acyltransferase family CFEM PF05730.6 KZN88385.1 - 3.3e-15 55.6 9.8 4.8e-15 55.1 6.8 1.2 1 0 0 1 1 1 1 CFEM domain ADH_zinc_N PF00107.21 KZN88387.1 - 1.7e-30 105.2 0.0 2.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88387.1 - 1.4e-19 71.2 0.0 2.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN88387.1 - 9.1e-12 44.7 0.0 1.5e-10 40.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Arb1 PF09692.5 KZN88388.1 - 1e-111 373.5 0.0 3e-111 372.0 0.0 1.7 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 KZN88389.1 - 5.3e-61 205.7 0.0 7.7e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 KZN88390.1 - 1e-20 73.0 0.0 1.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 KZN88391.1 - 1.8e-23 82.1 0.1 2.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TRF PF08558.5 KZN88392.1 - 3.5e-88 294.9 0.5 5.5e-88 294.3 0.3 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KZN88392.1 - 1.3e-05 25.0 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain His_Phos_2 PF00328.17 KZN88393.1 - 1.7e-12 47.3 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KZN88395.1 - 2e-70 236.9 0.0 3.3e-70 236.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88395.1 - 6.4e-30 104.0 0.0 2.1e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KZN88395.1 - 1.7e-08 33.7 0.2 0.005 15.8 0.0 3.1 2 1 1 3 3 3 2 Kinase-like APH PF01636.18 KZN88395.1 - 0.032 13.9 0.0 1.6 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KZN88395.1 - 0.074 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 KZN88395.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain FA_desaturase PF00487.19 KZN88396.1 - 1.7e-37 129.2 30.1 3.4e-37 128.2 20.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KZN88396.1 - 2.1e-13 49.8 0.0 4.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DASH_Dad3 PF08656.5 KZN88397.1 - 1e-11 44.3 0.2 1.4e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.10 KZN88398.1 - 1.7e-17 62.4 0.0 3.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KZN88398.1 - 8.6e-07 28.6 0.2 6.1e-06 25.8 0.0 2.3 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain Acetyltransf_11 PF13720.1 KZN88398.1 - 0.078 13.2 2.3 14 5.9 0.0 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 tRNA_U5-meth_tr PF05958.6 KZN88399.1 - 2.1e-12 46.4 0.0 1.1e-05 24.2 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KZN88399.1 - 7.4e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KZN88399.1 - 7.9e-06 25.5 0.1 3.1e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 KZN88399.1 - 0.044 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KZN88399.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Actin PF00022.14 KZN88400.1 - 3.6e-90 302.2 0.0 8.9e-90 300.9 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KZN88400.1 - 0.029 12.9 0.0 0.85 8.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KZN88401.1 - 4.3e-39 134.0 4.5 2.5e-20 72.4 0.1 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 KZN88402.1 - 1.3e-120 401.7 0.0 1.6e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 KZN88402.1 - 0.28 10.9 3.9 0.56 10.0 2.7 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type UNC45-central PF11701.3 KZN88403.1 - 1.3e-39 135.4 0.4 2.1e-38 131.4 0.1 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central TPR_11 PF13414.1 KZN88403.1 - 0.018 14.6 0.4 0.051 13.2 0.2 1.8 1 0 0 1 1 1 0 TPR repeat TPR_15 PF13429.1 KZN88403.1 - 0.024 13.7 0.2 0.043 12.8 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT_2 PF13646.1 KZN88403.1 - 1.6 9.0 21.3 0.14 12.4 2.1 6.0 5 3 2 7 7 7 0 HEAT repeats TPR_16 PF13432.1 KZN88403.1 - 1.7 9.3 12.1 2.3 8.9 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Arm PF00514.18 KZN88403.1 - 4.1 7.3 21.1 2.8 7.8 0.0 6.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat GDPD PF03009.12 KZN88404.1 - 3.1e-71 239.8 0.0 6.5e-71 238.8 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KZN88404.1 - 2.5e-33 114.2 0.1 1.1e-15 57.6 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN88404.1 - 3.4e-30 102.3 0.5 6.4e-06 25.7 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KZN88404.1 - 3.4e-29 100.6 2.9 1.1e-08 35.3 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 KZN88404.1 - 4.9e-27 95.4 7.0 1.3e-12 48.0 2.7 3.3 2 1 0 2 2 2 2 SPX domain Ank_3 PF13606.1 KZN88404.1 - 2.2e-19 67.5 0.2 0.00033 20.6 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KZN88404.1 - 3.6e-19 68.3 0.3 1.1e-06 28.6 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN88405.1 - 9.1e-06 25.3 1.6 9.1e-06 25.3 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN88405.1 - 4.1 7.1 7.0 32 4.3 0.1 3.5 3 0 0 3 3 3 0 F-box domain Polysacc_deac_1 PF01522.16 KZN88406.1 - 6.9e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 KZN88406.1 - 0.027 12.5 0.0 0.041 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 KZN88406.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Pyr_redox_2 PF07992.9 KZN88407.1 - 2.4e-15 56.9 0.0 3.9e-14 52.9 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN88407.1 - 6.2e-15 55.3 0.2 4.4e-11 43.0 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN88407.1 - 1.3e-05 25.0 1.9 5.2 6.8 0.1 4.2 3 1 1 4 4 4 3 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KZN88407.1 - 5.8e-05 22.1 2.1 0.021 13.7 0.0 3.2 4 0 0 4 4 4 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KZN88407.1 - 7.9e-05 22.8 1.1 2.6 8.0 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN88407.1 - 0.00026 19.9 1.0 2 7.2 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KZN88407.1 - 0.00047 19.1 0.4 0.6 8.9 0.0 2.7 1 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 KZN88407.1 - 0.061 13.3 0.8 14 5.6 0.1 3.6 3 1 0 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.9 KZN88407.1 - 0.062 11.9 0.5 2.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase DUF1188 PF06690.6 KZN88407.1 - 0.077 12.1 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) HNH_2 PF13391.1 KZN88408.1 - 1.2e-15 57.0 0.3 2.1e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.2 KZN88409.1 - 7.5e-87 285.8 19.8 7.4e-19 67.8 0.2 6.8 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN88409.1 - 9.8e-79 255.5 25.8 2.5e-06 26.9 0.0 14.1 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 KZN88409.1 - 4e-66 218.3 14.8 2.7e-11 43.6 0.0 9.4 6 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN88409.1 - 6.2e-61 196.2 17.3 0.0013 18.7 0.3 14.2 14 0 0 14 14 14 13 Ankyrin repeat Ank_5 PF13857.1 KZN88409.1 - 5.1e-52 172.7 24.7 6.7e-08 32.5 0.2 12.0 3 2 9 12 12 12 12 Ankyrin repeats (many copies) SchA_CurD PF04486.7 KZN88409.1 - 0.022 14.6 1.0 0.54 10.1 0.0 3.5 4 0 0 4 4 4 0 SchA/CurD like domain Cu-oxidase_3 PF07732.10 KZN88410.1 - 5.7e-38 129.2 0.0 1.9e-36 124.3 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN88410.1 - 9.4e-31 106.1 2.4 2.3e-23 82.2 0.1 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KZN88410.1 - 1.1e-15 57.8 0.0 1.9e-14 53.8 0.0 2.7 2 1 0 2 2 2 1 Multicopper oxidase HeLo PF14479.1 KZN88411.1 - 3.6e-48 164.1 2.3 4.6e-48 163.7 1.6 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation priB_priC PF07445.7 KZN88411.1 - 0.013 14.9 1.4 0.025 14.0 1.0 1.5 1 1 0 1 1 1 0 Primosomal replication protein priB and priC Fungal_trans_2 PF11951.3 KZN88412.1 - 7.3e-41 140.0 9.6 1.7e-21 76.2 2.8 2.0 1 1 0 2 2 2 2 Fungal specific transcription factor domain Arginase PF00491.16 KZN88413.1 - 2.3e-87 292.8 0.0 2.6e-87 292.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family p450 PF00067.17 KZN88414.1 - 7.7e-57 192.8 0.0 3.1e-56 190.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 KZN88416.1 - 4.8e-45 154.2 0.1 6e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2_4 PF13894.1 KZN88417.1 - 2.3e-07 30.6 8.7 0.00011 22.3 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN88417.1 - 8.3e-06 25.8 8.5 0.02 15.2 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN88417.1 - 0.16 12.3 12.6 0.27 11.6 4.9 2.8 2 0 0 2 2 2 0 Zinc-finger double domain CHORD PF04968.7 KZN88417.1 - 0.33 11.2 3.0 9.1 6.6 0.1 2.4 1 1 1 2 2 2 0 CHORD AA_permease_2 PF13520.1 KZN88418.1 - 1.3e-46 159.0 54.6 1.6e-46 158.7 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN88418.1 - 3.8e-23 81.5 45.8 5.6e-23 81.0 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease SARS_3b PF12383.3 KZN88419.1 - 0.091 12.6 0.6 0.4 10.5 0.1 2.2 1 1 1 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein Peptidase_S10 PF00450.17 KZN88421.1 - 1.1e-93 314.6 1.8 1.4e-93 314.3 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Lipase_3 PF01764.20 KZN88422.1 - 1.2e-36 125.3 0.0 1.8e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KZN88422.1 - 2.5e-22 78.4 0.1 5.9e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Cutinase PF01083.17 KZN88422.1 - 4.4e-05 23.2 0.1 9.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Cutinase Abhydrolase_5 PF12695.2 KZN88422.1 - 4.9e-05 23.1 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN88422.1 - 0.0001 22.2 0.1 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KZN88422.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Thioesterase PF00975.15 KZN88422.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 KZN88422.1 - 0.0047 16.3 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 PE-PPE domain Ser_hydrolase PF06821.8 KZN88422.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.15 KZN88422.1 - 0.037 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 KZN88422.1 - 0.056 12.8 0.7 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 KZN88422.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KZN88422.1 - 0.077 12.5 0.2 0.51 9.8 0.0 2.2 2 1 0 3 3 3 0 alpha/beta hydrolase fold DUF676 PF05057.9 KZN88422.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PRMT5 PF05185.11 KZN88423.1 - 1.2e-169 565.0 0.0 1.5e-169 564.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 KZN88424.1 - 2e-29 101.6 0.1 6.4e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KZN88424.1 - 2.9e-24 85.0 0.1 7.1e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN88424.1 - 8.1e-11 41.6 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN88424.1 - 3e-06 26.8 0.2 7.1e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN88424.1 - 0.00024 21.2 0.1 0.0009 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KZN88424.1 - 0.0011 18.4 0.3 0.003 17.0 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KZN88424.1 - 0.01 14.7 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KZN88424.1 - 0.051 13.1 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KZN88424.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.9 KZN88424.1 - 0.12 12.0 0.3 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_29 PF13555.1 KZN88424.1 - 0.18 11.3 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SAP18 PF06487.7 KZN88425.1 - 0.00067 19.4 0.1 0.0017 18.1 0.1 1.7 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) TPR_14 PF13428.1 KZN88425.1 - 0.005 17.3 0.7 7.5 7.4 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat EF-hand_6 PF13405.1 KZN88426.1 - 1e-09 37.4 0.1 0.00062 19.4 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KZN88426.1 - 0.00054 20.0 2.0 0.0048 16.9 0.1 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KZN88426.1 - 0.001 18.2 0.0 0.0034 16.5 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KZN88426.1 - 0.051 12.9 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 KZN88427.1 - 0.00016 21.3 0.1 0.15 11.9 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KZN88427.1 - 0.00042 19.2 0.0 0.0019 17.0 0.0 2.0 1 1 0 2 2 2 1 Coatomer WD associated region CNH PF00780.17 KZN88427.1 - 0.00087 18.7 0.1 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 CNH domain Hira PF07569.6 KZN88427.1 - 0.033 13.3 0.1 0.12 11.5 0.0 1.9 3 0 0 3 3 3 0 TUP1-like enhancer of split DNA_gyraseA_C PF03989.8 KZN88427.1 - 0.12 11.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Apc4_WD40 PF12894.2 KZN88427.1 - 0.12 11.9 0.0 8.2 6.0 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GST_N_2 PF13409.1 KZN88428.1 - 1.8e-20 72.7 0.0 3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN88428.1 - 5.7e-15 54.9 0.1 2.5e-14 52.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN88428.1 - 1.7e-05 24.6 0.1 4.6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN88428.1 - 4.5e-05 23.5 0.0 0.00089 19.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN88428.1 - 0.00021 21.6 0.0 0.00051 20.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSPc PF00782.15 KZN88429.1 - 3e-31 107.7 0.0 4e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KZN88429.1 - 9e-06 25.1 0.0 0.00043 19.6 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KZN88429.1 - 0.096 12.7 0.1 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate DNA_mis_repair PF01119.14 KZN88430.1 - 2.3e-33 114.1 0.2 3.8e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KZN88430.1 - 9.6e-16 57.6 0.0 2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KZN88430.1 - 6e-11 42.0 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PC_rep PF01851.17 KZN88432.1 - 2.3e-19 68.4 15.2 5.1e-05 23.2 0.1 8.1 9 0 0 9 9 9 4 Proteasome/cyclosome repeat TPR_5 PF12688.2 KZN88432.1 - 0.031 14.3 0.8 4.4 7.3 0.0 3.6 3 1 0 4 4 4 0 Tetratrico peptide repeat DUF2776 PF10951.3 KZN88432.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) RIO1 PF01163.17 KZN88433.1 - 5.7e-41 139.9 0.4 1e-28 100.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KZN88433.1 - 6.1e-30 103.1 0.0 1.9e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KZN88433.1 - 1e-06 28.7 0.0 0.0078 15.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN88433.1 - 5.3e-06 25.6 0.1 0.00019 20.5 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 KZN88433.1 - 0.6 7.9 11.3 0.72 7.6 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KZN88433.1 - 3.4 5.5 12.9 4.7 5.1 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KZN88433.1 - 4.6 6.3 9.3 7.2 5.7 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein APH PF01636.18 KZN88435.1 - 6.1e-05 22.8 0.5 0.0071 16.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN88435.1 - 0.0033 16.5 0.1 0.01 14.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L23 PF00276.15 KZN88436.1 - 4.8e-13 48.8 0.0 7.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.8 KZN88437.1 - 3.6e-70 235.4 0.2 1.1e-69 233.8 0.1 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KZN88437.1 - 3.3e-27 95.5 0.1 6.7e-27 94.5 0.0 1.6 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KZN88437.1 - 3.4e-23 82.3 0.0 2.2e-22 79.6 0.0 2.5 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KZN88437.1 - 2e-09 36.9 0.0 1.7e-08 34.0 0.0 2.3 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KZN88437.1 - 1.1e-07 31.6 0.0 3.3e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN88437.1 - 4.6e-07 30.0 0.1 3.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 KZN88437.1 - 1e-05 25.1 0.0 3e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KZN88437.1 - 1.4e-05 24.0 0.1 0.00013 20.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KZN88437.1 - 2.3e-05 25.1 0.0 0.0001 23.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN88437.1 - 5.4e-05 22.8 0.0 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN88437.1 - 0.00012 22.1 0.1 0.002 18.2 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KZN88437.1 - 0.00032 20.5 0.0 0.00089 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KZN88437.1 - 0.00035 20.5 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KZN88437.1 - 0.00047 19.2 0.1 0.0018 17.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KZN88437.1 - 0.00088 19.1 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN88437.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KZN88437.1 - 0.0026 16.9 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 KZN88437.1 - 0.006 16.1 0.2 0.29 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KZN88437.1 - 0.0086 15.8 0.0 0.59 9.7 0.0 2.9 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 KZN88437.1 - 0.018 14.4 0.0 0.057 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN88437.1 - 0.019 15.2 1.8 0.1 12.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 KZN88437.1 - 0.021 14.0 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 KZN88437.1 - 0.025 14.7 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KZN88437.1 - 0.031 13.9 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CCDC-167 PF15188.1 KZN88437.1 - 0.032 14.1 3.6 0.054 13.4 0.6 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mg_chelatase PF01078.16 KZN88437.1 - 0.041 13.0 0.1 0.1 11.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 KZN88437.1 - 0.061 12.0 0.0 0.39 9.3 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.1 KZN88437.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KZN88437.1 - 0.077 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KZN88437.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KZN88437.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KZN88437.1 - 0.12 12.6 5.3 0.25 11.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain Porphobil_deam PF01379.15 KZN88438.1 - 3.9e-78 261.2 0.0 5.1e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KZN88438.1 - 7.3e-17 61.2 0.3 1.3e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TAP42 PF04177.7 KZN88439.1 - 4.8e-104 347.9 1.0 5.4e-104 347.7 0.7 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.21 KZN88440.1 - 1.5e-44 151.0 0.1 1.3e-21 77.1 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN88440.1 - 1.8e-28 99.0 0.0 7.1e-15 55.0 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KZN88440.1 - 3.7e-21 74.6 0.8 2.7e-20 71.9 0.1 2.7 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 KZN88440.1 - 5.9e-15 54.8 0.1 1.7e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN88440.1 - 4.2e-11 43.0 0.0 2.4e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN88440.1 - 3.2e-10 39.7 0.0 8.1e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KZN88440.1 - 0.00012 21.0 0.0 0.00022 20.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain dsrm PF00035.20 KZN88440.1 - 0.021 15.3 0.2 7.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF2075 PF09848.4 KZN88440.1 - 0.041 12.8 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DHC_N1 PF08385.7 KZN88441.1 - 2.3e-186 620.6 5.1 2.3e-186 620.6 3.6 5.1 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KZN88441.1 - 4.9e-128 427.1 5.5 4.9e-128 427.1 3.8 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KZN88441.1 - 8.1e-105 351.4 0.0 2.3e-104 349.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KZN88441.1 - 2.7e-77 259.3 0.0 7.2e-77 258.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KZN88441.1 - 2.5e-43 147.5 0.9 7.6e-43 145.9 0.0 2.4 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 MT PF12777.2 KZN88441.1 - 1.7e-42 145.4 8.4 3.9e-42 144.2 5.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 KZN88441.1 - 1.4e-40 138.9 0.0 9.3e-40 136.2 0.0 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KZN88441.1 - 3.5e-32 111.0 0.2 6.1e-10 38.9 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KZN88441.1 - 1.7e-19 69.9 0.1 1e-18 67.4 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 KZN88441.1 - 8e-15 55.2 0.0 8.1e-05 22.8 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN88441.1 - 1.1e-14 54.7 0.0 0.0075 16.4 0.0 6.1 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.1 KZN88441.1 - 1.1e-08 35.0 0.8 0.37 10.6 0.1 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 KZN88441.1 - 4.4e-08 33.4 2.2 0.019 15.2 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_17 PF13207.1 KZN88441.1 - 6e-08 33.5 0.1 0.04 14.7 0.0 5.5 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 KZN88441.1 - 5.3e-07 28.8 0.0 0.026 13.4 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.1 KZN88441.1 - 2.1e-06 27.8 6.4 0.1 12.5 0.1 7.4 6 1 1 7 7 7 1 AAA ATPase domain ABC_tran PF00005.22 KZN88441.1 - 5e-06 26.8 0.5 0.95 9.7 0.1 5.2 4 0 0 4 4 3 2 ABC transporter AAA_14 PF13173.1 KZN88441.1 - 1.7e-05 24.7 0.0 0.23 11.3 0.0 4.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KZN88441.1 - 2.2e-05 23.8 0.0 2 7.9 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KZN88441.1 - 2.9e-05 23.7 0.3 0.43 10.3 0.0 4.3 4 0 0 4 4 4 1 Part of AAA domain Zeta_toxin PF06414.7 KZN88441.1 - 3.5e-05 22.9 0.3 0.46 9.5 0.0 4.0 4 0 0 4 4 3 2 Zeta toxin Mg_chelatase PF01078.16 KZN88441.1 - 0.00018 20.7 0.9 0.45 9.6 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KZN88441.1 - 0.0015 17.9 0.7 0.25 10.7 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KZN88441.1 - 0.01 15.9 0.2 27 5.0 0.0 4.6 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KZN88441.1 - 0.021 14.2 1.3 0.48 9.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF3762 PF12591.3 KZN88441.1 - 0.18 11.8 0.1 0.68 9.9 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3762) ERM PF00769.14 KZN88441.1 - 0.39 10.2 24.6 0.13 11.7 0.8 3.0 3 0 0 3 3 2 0 Ezrin/radixin/moesin family Svf1 PF08622.5 KZN88442.1 - 9.5e-133 442.1 0.1 1.1e-132 441.9 0.1 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 KZN88442.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.4 1 1 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Ribosomal_L11_N PF03946.9 KZN88443.1 - 1.8e-26 91.3 0.1 3.1e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KZN88443.1 - 7.9e-23 80.3 0.0 1.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 KZN88444.1 - 2.3e-57 194.0 0.0 9e-57 192.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88444.1 - 7.9e-19 67.7 0.0 1.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN88444.1 - 0.022 14.4 0.4 0.048 13.3 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.22 KZN88445.1 - 3.1e-42 142.2 2.7 8.8e-15 54.1 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Cupin_5 PF06172.6 KZN88446.1 - 8.9e-26 90.4 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily (DUF985) CaMKII_AD PF08332.5 KZN88446.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DUF3337 PF11816.3 KZN88447.1 - 7.2e-95 318.1 0.0 1.1e-90 304.3 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KZN88447.1 - 1.5e-26 91.2 16.7 1.7e-08 34.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_2 PF07719.12 KZN88448.1 - 2.9e-14 51.7 4.9 0.0041 16.9 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KZN88448.1 - 1.9e-12 46.6 1.2 0.00048 19.7 0.1 4.5 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 KZN88448.1 - 2.7e-08 33.0 0.9 0.17 11.5 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN88448.1 - 7.3e-07 29.0 8.7 0.17 11.8 1.6 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88448.1 - 2.9e-06 27.5 9.9 0.0025 18.1 0.1 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88448.1 - 5.5e-06 26.9 19.2 0.00083 19.9 1.3 6.2 5 2 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KZN88448.1 - 6.8e-05 22.9 12.0 1 10.0 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88448.1 - 0.00044 20.6 15.3 2.1 9.2 1.0 8.2 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 KZN88448.1 - 0.00054 19.5 0.0 5 7.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN88448.1 - 0.0026 17.8 0.1 17 5.9 0.0 4.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KZN88448.1 - 0.013 15.6 0.9 1.2 9.2 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KZN88448.1 - 0.016 14.9 6.7 23 5.1 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 KZN88448.1 - 0.023 14.9 2.9 0.079 13.2 0.5 3.1 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ofd1_CTDD PF10637.4 KZN88448.1 - 0.065 12.3 0.3 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Fungal_trans PF04082.13 KZN88449.1 - 0.014 14.3 1.3 0.031 13.1 0.9 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain ATP_bind_3 PF01171.15 KZN88450.1 - 2.2e-37 128.2 0.0 3e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 KZN88450.1 - 0.056 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 KZN88451.1 - 1.2e-22 80.6 0.0 4.2e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 KZN88451.1 - 3e-06 26.8 0.0 6.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGAP PF00620.22 KZN88451.1 - 0.082 12.5 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 RhoGAP domain Sec7 PF01369.15 KZN88452.1 - 1e-58 198.1 0.0 1.7e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KZN88452.1 - 7e-20 71.1 0.1 2.3e-12 46.6 0.0 3.5 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal APC2 PF08672.6 KZN88452.1 - 0.09 13.0 0.0 11 6.3 0.1 3.0 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 TPR_14 PF13428.1 KZN88453.1 - 1.1e-11 44.2 10.6 1.3 9.8 0.0 11.0 11 2 2 13 13 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN88453.1 - 2.5e-10 40.1 6.3 2.1 8.3 0.0 7.7 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88453.1 - 6.4e-10 39.2 0.1 0.32 11.3 0.0 6.1 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 KZN88453.1 - 6.9e-08 32.5 14.9 0.035 13.8 0.3 6.1 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 KZN88453.1 - 2.9e-07 30.0 9.2 0.083 12.5 0.0 6.9 8 0 0 8 8 6 2 TPR repeat Mad3_BUB1_I PF08311.7 KZN88453.1 - 4.3e-07 29.7 12.4 0.39 10.5 0.2 6.6 6 1 0 6 6 6 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 KZN88453.1 - 1.4e-06 27.7 15.5 0.96 9.5 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88453.1 - 5.5e-06 26.9 6.0 0.086 13.5 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KZN88453.1 - 7.7e-06 25.3 3.8 0.22 11.4 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KZN88453.1 - 1e-05 24.7 7.1 0.0026 16.8 1.9 4.0 5 1 1 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.1 KZN88453.1 - 2.9e-05 23.3 3.0 0.083 12.0 0.1 4.4 5 1 0 5 5 5 2 Soluble NSF attachment protein, SNAP NRDE-2 PF08424.5 KZN88453.1 - 0.00021 20.3 7.6 0.18 10.6 0.4 4.5 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 KZN88453.1 - 0.004 17.2 8.9 0.06 13.5 0.0 6.0 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN88453.1 - 0.0089 15.7 8.9 11 6.1 0.0 7.8 10 0 0 10 10 9 0 Tetratricopeptide repeat HAT PF02184.11 KZN88453.1 - 0.069 12.9 4.4 2.6 7.8 0.0 5.4 7 0 0 7 7 6 0 HAT (Half-A-TPR) repeat CKAP2_C PF15297.1 KZN88453.1 - 0.088 11.5 0.1 0.26 10.0 0.1 1.8 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TPR_6 PF13174.1 KZN88453.1 - 0.55 10.8 12.0 1.4 9.5 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Esterase_phd PF10503.4 KZN88454.1 - 8.8e-06 25.1 0.1 1.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KZN88454.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN88454.1 - 0.02 14.1 0.3 0.045 12.9 0.2 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family TFCD_C PF12612.3 KZN88455.1 - 1.7e-44 151.5 0.2 2e-43 148.0 0.1 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal MatE PF01554.13 KZN88455.1 - 1.6e-35 122.1 28.3 2.3e-25 89.0 6.0 3.1 3 0 0 3 3 3 2 MatE HEAT PF02985.17 KZN88455.1 - 0.019 15.0 12.7 1.6 9.0 0.0 7.6 8 0 0 8 8 8 0 HEAT repeat HEAT_2 PF13646.1 KZN88455.1 - 0.025 14.8 9.4 2.3 8.5 0.0 5.3 5 1 1 6 6 6 0 HEAT repeats Pkinase PF00069.20 KZN88457.1 - 3.4e-61 206.6 0.0 5.3e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88457.1 - 1e-34 119.7 0.0 1.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KZN88457.1 - 1.4e-33 114.4 14.1 2.5e-19 68.7 2.9 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KZN88457.1 - 2.6e-20 71.8 30.1 1.2e-11 44.0 6.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KZN88457.1 - 1.9e-14 53.8 3.3 6.6e-14 52.1 2.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KZN88457.1 - 0.079 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peptidase_M6 PF05547.6 KZN88457.1 - 0.17 9.8 0.3 0.89 7.5 0.0 1.9 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 Uds1 PF15456.1 KZN88457.1 - 2 8.4 6.2 0.26 11.3 0.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation eIF-1a PF01176.14 KZN88458.1 - 3.8e-14 51.8 0.3 6.6e-14 51.0 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Enkurin PF13864.1 KZN88458.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Calmodulin-binding ALG3 PF05208.8 KZN88459.1 - 3.1e-128 428.1 21.1 3.6e-128 427.9 14.6 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 KZN88459.1 - 0.035 13.0 16.1 0.048 12.5 11.1 1.3 1 0 0 1 1 1 0 EpsG family DUF3628 PF12300.3 KZN88460.1 - 0.011 15.7 0.2 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) NSP2-B_epitope PF14757.1 KZN88460.1 - 0.017 14.6 0.2 0.022 14.2 0.2 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Metallophos PF00149.23 KZN88461.1 - 4.3e-36 124.1 0.3 2.2e-29 102.3 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 KZN88462.1 - 1e-42 145.7 0.4 1.9e-42 144.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88462.1 - 3.8e-08 33.1 8.2 7.6e-08 32.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 KZN88462.1 - 0.0057 16.3 5.3 0.0071 16.0 2.8 1.8 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 KZN88462.1 - 1.1 9.0 9.0 2 8.1 6.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DNA_ligase_A_M PF01068.16 KZN88464.1 - 3.1e-47 160.5 0.0 3.5e-46 157.1 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KZN88464.1 - 2.5e-41 141.4 0.0 1e-40 139.4 0.0 2.1 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KZN88464.1 - 3.9e-18 65.6 0.4 1.6e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KZN88464.1 - 4.8e-08 33.0 0.0 3.3e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KZN88464.1 - 1.8e-05 24.3 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV RNA_ligase PF09414.5 KZN88464.1 - 0.0039 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.14 KZN88464.1 - 0.009 15.7 0.1 0.33 10.6 0.0 3.0 2 2 0 2 2 2 1 mRNA capping enzyme, catalytic domain DUF2072 PF09845.4 KZN88464.1 - 1.6 8.6 5.4 0.24 11.3 0.4 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Fungal_trans PF04082.13 KZN88465.1 - 1.1e-19 70.4 2.3 2.4e-19 69.2 1.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KZN88465.1 - 2.9e-07 30.4 8.7 1.5e-06 28.2 3.6 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KZN88465.1 - 9.5e-06 25.6 23.7 0.00038 20.6 2.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KZN88465.1 - 1.7e-05 24.6 7.9 1.7e-05 24.6 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KZN88465.1 - 9.9e-05 22.4 23.3 0.00019 21.4 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KZN88465.1 - 0.015 15.4 0.6 0.015 15.4 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN88465.1 - 0.02 15.0 6.0 0.95 9.6 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EF-hand_4 PF12763.2 KZN88466.1 - 0.00061 19.4 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Zn_clus PF00172.13 KZN88467.1 - 5.3e-07 29.4 6.3 1.4e-06 28.0 4.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88467.1 - 2e-06 26.8 2.0 5.5e-06 25.4 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spb1_C PF07780.7 KZN88469.1 - 4.4e-74 248.5 28.8 4.4e-74 248.5 20.0 4.5 2 1 2 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 KZN88469.1 - 2.8e-55 186.1 8.6 2.8e-55 186.1 5.9 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KZN88469.1 - 3.4e-54 183.5 0.0 6.4e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DOT1 PF08123.8 KZN88470.1 - 7.8e-78 260.4 0.0 1.1e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KZN88470.1 - 0.00029 20.8 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88470.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.6 KZN88471.1 - 1.2e-52 178.5 14.2 1.4e-52 178.3 9.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KZN88471.1 - 0.0037 15.9 7.1 0.0057 15.3 4.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CCDC144C PF14915.1 KZN88471.1 - 0.0058 15.5 9.1 0.0058 15.5 6.3 1.5 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region Ring_hydroxyl_B PF00866.13 KZN88471.1 - 0.007 16.0 1.9 0.32 10.6 0.5 2.3 2 0 0 2 2 2 1 Ring hydroxylating beta subunit IncA PF04156.9 KZN88471.1 - 0.028 14.0 13.2 0.042 13.4 9.1 1.4 1 1 0 1 1 1 0 IncA protein Nup54 PF13874.1 KZN88471.1 - 0.038 13.6 11.5 0.082 12.5 2.2 2.4 2 1 1 3 3 2 0 Nucleoporin complex subunit 54 DUF3450 PF11932.3 KZN88471.1 - 0.044 13.0 5.3 0.071 12.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 KZN88471.1 - 0.049 12.5 7.5 0.061 12.2 5.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 KZN88471.1 - 0.062 12.7 16.8 0.021 14.2 9.9 1.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TBPIP PF07106.8 KZN88471.1 - 0.07 12.6 6.6 0.11 12.0 4.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4201 PF13870.1 KZN88471.1 - 0.11 11.8 14.8 0.034 13.5 8.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) MscS_porin PF12795.2 KZN88471.1 - 0.13 11.5 21.4 0.62 9.3 4.7 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain APG6 PF04111.7 KZN88471.1 - 0.22 10.5 10.1 0.35 9.8 7.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 KZN88471.1 - 0.36 10.7 9.0 4.2 7.3 0.1 3.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CENP-F_leu_zip PF10473.4 KZN88471.1 - 0.43 10.4 13.7 0.71 9.7 9.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.10 KZN88471.1 - 0.69 9.9 15.6 0.41 10.6 6.7 2.2 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.7 KZN88471.1 - 0.83 9.4 5.1 8.8 6.1 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KZN88471.1 - 0.93 7.2 6.9 1.3 6.7 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KZN88471.1 - 1 9.7 11.1 2.8 8.3 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KZN88471.1 - 1.7 8.4 11.4 1.2 8.9 0.6 2.6 2 1 1 3 3 3 0 Prefoldin subunit CCDC-167 PF15188.1 KZN88471.1 - 2.2 8.2 15.5 3.3 7.7 1.4 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 GrpE PF01025.14 KZN88471.1 - 3.4 7.1 11.7 0.43 10.0 1.3 2.4 1 1 1 2 2 2 0 GrpE DUF4140 PF13600.1 KZN88471.1 - 4.3 7.8 14.2 4.2 7.8 1.0 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) YlqD PF11068.3 KZN88471.1 - 7.9 6.5 8.4 5.8 6.9 4.1 2.0 2 1 0 2 2 2 0 YlqD protein TSC22 PF01166.13 KZN88471.1 - 9.6 6.2 8.3 2 8.4 0.7 2.8 1 1 0 2 2 2 0 TSC-22/dip/bun family Ras PF00071.17 KZN88472.1 - 1.1e-56 190.6 0.1 1.3e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN88472.1 - 1.9e-19 70.2 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN88472.1 - 9.5e-13 47.7 0.0 1.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KZN88472.1 - 5.9e-07 29.4 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN88472.1 - 1.4e-06 27.8 0.0 2.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN88472.1 - 2.9e-06 26.6 0.0 3.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KZN88472.1 - 0.001 19.2 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KZN88472.1 - 0.001 18.5 0.0 0.012 15.1 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KZN88472.1 - 0.0012 18.0 0.1 0.0025 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KZN88472.1 - 0.0016 18.0 0.2 0.056 12.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KZN88472.1 - 0.0024 17.3 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KZN88472.1 - 0.0049 16.4 0.1 0.0085 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 KZN88472.1 - 0.0064 15.5 0.1 0.057 12.4 0.0 2.1 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 KZN88472.1 - 0.0074 16.0 0.5 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 KZN88472.1 - 0.0088 16.0 0.0 0.051 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KZN88472.1 - 0.012 15.2 0.0 0.027 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KZN88472.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 NTPase SRPRB PF09439.5 KZN88472.1 - 0.024 13.8 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KZN88472.1 - 0.026 13.9 0.3 0.058 12.8 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KZN88472.1 - 0.048 13.3 0.4 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KZN88472.1 - 0.067 12.8 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 KZN88472.1 - 0.14 11.4 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B EamA PF00892.15 KZN88473.1 - 4.2e-07 30.0 4.6 4.2e-07 30.0 3.2 3.3 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KZN88473.1 - 7.1e-06 25.1 9.9 1.2e-05 24.3 6.9 1.3 1 0 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 KZN88473.1 - 0.00039 19.3 4.2 0.00039 19.3 2.9 2.1 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KZN88473.1 - 0.0014 18.8 4.6 0.0014 18.8 3.2 3.8 3 2 0 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 KZN88473.1 - 0.085 12.5 28.7 0.012 15.2 7.2 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family PH PF00169.24 KZN88474.1 - 9.7e-26 89.9 0.1 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KZN88474.1 - 1.3e-11 44.7 0.3 2.6e-05 24.4 0.0 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KZN88474.1 - 6.4e-10 39.2 0.2 5.7e-05 23.2 0.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain Glyco_transf_15 PF01793.11 KZN88475.1 - 3.3e-132 440.4 3.6 4.1e-132 440.1 2.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Cyt-b5 PF00173.23 KZN88476.1 - 1.1e-09 37.8 0.0 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 KZN88478.1 - 1.7e-27 96.0 46.1 1.7e-27 96.0 31.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 KZN88478.1 - 0.49 10.5 6.3 0.52 10.5 0.5 3.5 3 1 0 3 3 3 0 Phage holin Peptidase_S76 PF13611.1 KZN88479.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 BRCT_assoc PF12820.2 KZN88479.1 - 0.038 13.7 0.6 0.082 12.6 0.4 1.5 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT Ran_BP1 PF00638.13 KZN88480.1 - 1.6e-48 163.7 2.6 1.6e-48 163.7 1.8 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 KZN88480.1 - 1.8e-05 24.3 0.5 0.0001 22.0 0.4 1.9 1 1 0 1 1 1 1 WH1 domain CDC27 PF09507.5 KZN88480.1 - 1 8.4 23.2 1.4 8.0 16.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FHIPEP PF00771.15 KZN88480.1 - 1.3 7.2 3.1 1.6 7.0 1.8 1.3 1 1 0 1 1 1 0 FHIPEP family TMEM247 PF15444.1 KZN88480.1 - 1.8 8.3 9.3 2.7 7.7 6.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 YEATS PF03366.11 KZN88481.1 - 2.2e-21 75.3 0.2 4e-21 74.5 0.2 1.4 1 0 0 1 1 1 1 YEATS family Phosducin PF02114.11 KZN88482.1 - 9.5e-16 57.3 0.0 2.4e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Phosducin TIMELESS_C PF05029.8 KZN88482.1 - 0.49 9.2 5.1 3.4 6.4 1.1 2.2 2 0 0 2 2 2 0 Timeless protein C terminal region WD40 PF00400.27 KZN88483.1 - 2.5e-52 172.9 22.5 1.1e-08 34.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KZN88483.1 - 6.2e-05 22.7 0.0 0.09 12.4 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 KZN88483.1 - 0.4 9.8 1.2 0.57 9.3 0.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 zf-MYND PF01753.13 KZN88484.1 - 2.1e-07 30.7 20.6 4.4e-07 29.6 14.3 1.6 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.1 KZN88485.1 - 2.2e-19 70.1 0.0 3.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN88485.1 - 2e-11 44.0 0.0 7.5e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 KZN88486.1 - 1.1e-74 250.4 0.0 1.5e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KZN88486.1 - 3.6e-30 104.1 0.0 9.1e-30 102.8 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KZN88486.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KZN88486.1 - 0.00014 22.0 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin PF00085.15 KZN88487.1 - 4.6e-60 199.7 0.0 4.1e-29 100.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KZN88487.1 - 9.9e-22 77.3 1.3 2.3e-21 76.2 0.9 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KZN88487.1 - 3e-19 69.2 0.4 5e-09 36.3 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KZN88487.1 - 8.1e-15 54.6 0.0 1.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KZN88487.1 - 5.7e-12 45.6 0.0 0.00013 21.9 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 KZN88487.1 - 6.5e-08 32.3 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 KZN88487.1 - 4.8e-06 26.5 0.6 0.17 11.7 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 KZN88487.1 - 5.4e-06 26.0 0.4 0.088 12.3 0.1 2.7 2 1 1 3 3 3 2 Redoxin Glutaredoxin PF00462.19 KZN88487.1 - 0.0013 18.6 0.5 2.6 8.1 0.0 3.1 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.1 KZN88487.1 - 0.0029 17.1 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 KZN88487.1 - 0.0045 16.7 0.0 3.8 7.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KZN88487.1 - 0.01 15.8 2.3 14 5.6 0.0 4.0 3 2 2 5 5 5 0 Thioredoxin TraF PF13728.1 KZN88487.1 - 0.061 12.8 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein HSBP1 PF06825.7 KZN88488.1 - 1.8e-18 65.8 0.2 3.2e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KZN88488.1 - 0.00052 19.3 1.5 0.092 12.1 0.1 2.2 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 KZN88488.1 - 0.011 15.5 0.2 0.014 15.2 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KZN88488.1 - 0.018 15.2 0.3 0.028 14.6 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.1 KZN88488.1 - 0.021 14.9 0.2 0.032 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Vinculin PF01044.14 KZN88488.1 - 0.036 12.1 0.0 0.041 11.9 0.0 1.0 1 0 0 1 1 1 0 Vinculin family Prp19 PF08606.6 KZN88488.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Prp19/Pso4-like Ebp2 PF05890.7 KZN88489.1 - 2.3e-91 305.8 17.3 2.3e-91 305.8 12.0 2.1 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CPSF100_C PF13299.1 KZN88489.1 - 0.84 9.8 17.2 1.7 8.8 6.1 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Spore_coat_CotO PF14153.1 KZN88489.1 - 1.8 7.9 30.8 0.046 13.1 11.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Prothymosin PF03247.9 KZN88489.1 - 2.2 8.4 55.1 1 9.5 27.8 3.0 2 1 1 3 3 3 0 Prothymosin/parathymosin family TruB_N PF01509.13 KZN88490.1 - 1.3e-45 155.2 0.1 5.4e-45 153.1 0.0 2.0 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) Baculo_PP31 PF05311.6 KZN88490.1 - 0.03 13.5 0.0 0.085 12.1 0.0 1.7 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DNMT1-RFD PF12047.3 KZN88491.1 - 1.9e-05 24.4 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain OHCU_decarbox PF09349.5 KZN88493.1 - 2.7e-50 170.7 0.0 3.1e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Tymo_45kd_70kd PF03251.8 KZN88493.1 - 0.042 12.5 0.4 0.053 12.2 0.3 1.0 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein HBS1_N PF08938.5 KZN88493.1 - 0.22 11.6 1.8 11 6.1 0.1 2.2 2 0 0 2 2 2 0 HBS1 N-terminus WD40 PF00400.27 KZN88494.1 - 2.1e-32 109.8 6.9 2.4e-10 39.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nbas_N PF15492.1 KZN88494.1 - 0.096 11.7 0.0 9.2 5.2 0.0 3.4 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal SRP9-21 PF05486.7 KZN88495.1 - 5.7e-31 106.0 0.3 7.1e-31 105.7 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 KZN88496.1 - 4.7e-121 403.1 1.0 5.6e-121 402.8 0.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.5 KZN88496.1 - 0.0094 14.8 0.2 1 8.1 0.0 2.1 2 0 0 2 2 2 2 XcyI restriction endonuclease Mito_carr PF00153.22 KZN88497.1 - 2.2e-58 193.9 4.1 1.5e-20 72.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KZN88498.1 - 9.1e-12 44.3 4.6 8.3e-06 25.4 0.0 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF3312 PF11768.3 KZN88498.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1308 PF07000.6 KZN88499.1 - 1.1e-98 330.2 0.0 1.6e-98 329.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) NmrA PF05368.8 KZN88500.1 - 1.2e-14 54.1 0.0 1.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN88500.1 - 2.2e-12 47.3 0.1 1.7e-11 44.5 0.0 2.1 1 1 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KZN88500.1 - 6.2e-05 22.1 0.0 9.9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KZN88500.1 - 0.068 12.5 0.1 0.6 9.4 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN88500.1 - 0.073 11.7 0.0 0.17 10.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 KZN88501.1 - 2.1e-09 36.6 0.3 2.7e-09 36.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88501.1 - 1.3e-07 31.3 13.3 2.2e-07 30.6 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1098 PF06497.6 KZN88501.1 - 0.0071 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1098) Lung_7-TM_R PF06814.8 KZN88502.1 - 1.2e-68 231.2 16.5 1.4e-68 231.0 11.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KZN88502.1 - 0.083 13.0 16.4 0.53 10.4 0.6 3.5 2 2 1 3 3 3 0 PrgI family protein DUF2392 PF10288.4 KZN88503.1 - 4.7e-25 87.9 0.0 9.6e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) XdhC_C PF13478.1 KZN88503.1 - 0.15 12.4 0.0 0.37 11.0 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain DUF4112 PF13430.1 KZN88504.1 - 2.3e-33 114.3 0.4 2.9e-33 113.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 KZN88505.1 - 4.3e-36 122.6 1.7 7.8e-36 121.8 1.2 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KZN88505.1 - 3.4e-17 62.3 0.1 6.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 KZN88506.1 - 1.3e-12 47.5 0.0 3.1e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KZN88506.1 - 0.00056 19.8 0.0 0.0016 18.4 0.0 1.8 1 1 1 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain VIT_2 PF13757.1 KZN88506.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DnaJ PF00226.26 KZN88507.1 - 1.1e-19 69.9 0.8 3e-19 68.4 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain Mei4 PF13971.1 KZN88508.1 - 0.0074 15.2 4.8 0.018 14.0 0.0 2.4 2 0 0 2 2 2 1 Meiosis-specific protein Mei4 Amidohydro_2 PF04909.9 KZN88509.1 - 1e-34 120.3 0.3 3.8e-34 118.5 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KZN88509.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase EthD PF07110.6 KZN88510.1 - 0.024 15.5 0.0 0.039 14.8 0.0 1.3 1 1 0 1 1 1 0 EthD domain DIOX_N PF14226.1 KZN88512.1 - 8.6e-24 84.3 0.0 2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN88512.1 - 6.1e-17 61.7 0.0 1.3e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 KZN88513.1 - 5.2e-19 68.7 0.3 1.5e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88513.1 - 1.6e-14 54.3 0.1 3.9e-13 49.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88513.1 - 1.6e-07 31.1 0.4 6.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KZN88513.1 - 0.00032 19.7 0.2 0.00059 18.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KZN88513.1 - 0.0022 16.7 0.5 0.0053 15.4 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KZN88513.1 - 0.0022 18.0 0.1 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KZN88513.1 - 0.0063 15.9 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KZN88513.1 - 0.041 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Saccharop_dh PF03435.13 KZN88513.1 - 0.055 12.4 0.2 0.081 11.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KZN88513.1 - 0.12 12.3 0.3 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding GFO_IDH_MocA PF01408.17 KZN88514.1 - 8.7e-19 68.2 0.1 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN88514.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.3 KZN88515.1 - 0.0082 14.7 0.2 0.014 13.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain KRAB PF01352.22 KZN88515.1 - 0.036 13.5 1.1 0.1 12.0 0.8 1.8 1 0 0 1 1 1 0 KRAB box Ferritin_2 PF13668.1 KZN88518.1 - 6.6e-18 64.9 0.1 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KZN88518.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.7 1 1 0 1 1 1 0 Rubrerythrin Trep_Strep PF09605.5 KZN88519.1 - 0.12 12.0 1.7 0.19 11.3 1.2 1.3 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) AMP-binding PF00501.23 KZN88520.1 - 1.4e-72 244.4 0.0 2.1e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN88520.1 - 5.1e-15 56.1 0.0 1.3e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GpcrRhopsn4 PF10192.4 KZN88521.1 - 2.1 7.5 9.0 0.13 11.4 2.5 1.6 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Response_reg PF00072.19 KZN88522.1 - 7.9e-23 80.5 0.3 1.6e-22 79.6 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KZN88522.1 - 6.9e-17 61.1 0.1 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KZN88522.1 - 4.7e-10 39.3 0.1 1.6e-09 37.6 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KZN88522.1 - 0.0013 18.7 0.0 0.033 14.2 0.0 2.6 2 0 0 2 2 2 1 GAF domain DUF1002 PF06207.6 KZN88522.1 - 0.16 11.2 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) CoA_transf_3 PF02515.12 KZN88523.1 - 4.1e-32 110.9 0.0 3.7e-31 107.8 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III ABC_tran PF00005.22 KZN88524.1 - 1.1e-25 90.4 0.0 9.2e-14 51.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KZN88524.1 - 2.1e-13 50.8 1.1 1.3e-05 25.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KZN88524.1 - 2.8e-06 27.1 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KZN88524.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN88524.1 - 0.0035 17.4 0.1 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KZN88524.1 - 0.0043 17.4 0.2 0.0086 16.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KZN88524.1 - 0.014 14.6 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 KZN88524.1 - 0.023 14.1 0.1 11 5.3 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.1 KZN88524.1 - 0.023 13.7 0.0 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KZN88524.1 - 0.029 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KZN88524.1 - 0.044 13.7 0.1 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_10 PF12846.2 KZN88524.1 - 0.06 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 KZN88524.1 - 0.11 11.8 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 KZN88524.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN88524.1 - 0.21 10.7 0.0 0.45 9.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MscL PF01741.13 KZN88525.1 - 1.7e-13 50.8 1.3 4.4e-13 49.4 0.9 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-ribbon_3 PF13248.1 KZN88525.1 - 0.0097 15.0 0.9 0.017 14.3 0.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KZN88525.1 - 0.019 14.4 0.7 0.037 13.5 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KZN88525.1 - 0.021 14.5 1.9 0.038 13.6 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.7 KZN88525.1 - 0.029 14.4 0.9 0.057 13.5 0.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 KZN88525.1 - 0.074 12.8 1.1 0.13 12.1 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon PLAC8 PF04749.12 KZN88529.1 - 1.6e-22 80.0 10.0 2.3e-22 79.5 6.9 1.2 1 0 0 1 1 1 1 PLAC8 family DUF605 PF04652.11 KZN88529.1 - 6.9 5.9 11.0 10 5.3 7.6 1.3 1 0 0 1 1 1 0 Vta1 like IPK PF03770.11 KZN88531.1 - 7.1e-58 195.4 0.0 1.2e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 KZN88531.1 - 0.094 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 KZN88532.1 - 1.3e-21 76.7 11.8 1.3e-21 76.7 8.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KZN88532.1 - 4.5e-08 32.6 3.1 3.4e-07 29.7 1.3 2.1 2 0 0 2 2 2 1 Nodulin-like PVL_ORF50 PF07768.6 KZN88532.1 - 0.044 13.7 0.9 0.092 12.7 0.6 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Glycos_transf_1 PF00534.15 KZN88533.1 - 9.6e-30 103.2 0.1 3e-28 98.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 ERCC4 PF02732.10 KZN88533.1 - 2.2e-25 89.0 0.0 4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Glyco_transf_4 PF13439.1 KZN88533.1 - 1.3e-10 41.3 0.0 3.8e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KZN88533.1 - 9.9e-08 32.2 2.9 9.9e-08 32.2 2.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KZN88533.1 - 5.3e-07 29.8 0.0 0.00021 21.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KZN88533.1 - 0.00065 19.9 0.0 0.0022 18.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Vma12 PF11712.3 KZN88534.1 - 2.4 7.8 5.1 1.1 8.9 1.4 2.1 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Kinesin PF00225.18 KZN88535.1 - 1.8e-91 306.3 0.1 1.8e-91 306.3 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Cu-oxidase_2 PF07731.9 KZN88536.1 - 2.3e-46 156.7 5.8 2.2e-41 140.6 0.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN88536.1 - 3.6e-41 139.5 7.2 2.5e-39 133.6 1.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KZN88536.1 - 2.8e-35 121.5 1.2 2.5e-32 111.9 0.3 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 KZN88536.1 - 0.12 12.2 0.0 30 4.5 0.0 3.2 4 0 0 4 4 4 0 Cupredoxin-like domain FTR1 PF03239.9 KZN88537.1 - 1.7e-85 286.6 4.8 2e-85 286.4 3.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.3 KZN88537.1 - 0.089 11.9 0.4 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Wzy_C PF04932.10 KZN88537.1 - 0.3 10.8 6.2 0.097 12.4 0.2 2.6 2 2 0 2 2 2 0 O-Antigen ligase DUF1043 PF06295.7 KZN88537.1 - 0.52 9.9 1.6 2.4 7.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) YjgP_YjgQ PF03739.9 KZN88537.1 - 0.57 8.8 7.4 0.84 8.3 3.4 2.3 2 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family NAD_binding_6 PF08030.7 KZN88538.1 - 4.3e-24 85.1 0.0 5.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KZN88538.1 - 3.2e-11 43.0 0.0 1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KZN88538.1 - 0.0013 18.7 2.5 0.0013 18.7 1.7 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KZN88538.1 - 0.0093 16.5 0.0 0.13 12.8 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain DUF2208 PF09973.4 KZN88538.1 - 4.9 6.3 8.6 10 5.2 6.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) CRAL_TRIO PF00650.15 KZN88539.1 - 3.2e-39 133.9 0.0 4.4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN88539.1 - 1.8e-12 47.1 0.1 4.8e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KZN88539.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Mec-17 PF05301.6 KZN88539.1 - 0.001 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 HrpB_C PF08482.5 KZN88539.1 - 0.0028 17.7 0.1 0.029 14.5 0.0 2.2 1 1 1 2 2 2 1 ATP-dependent helicase C-terminal Pol_alpha_B_N PF08418.5 KZN88540.1 - 3.4e-62 210.2 0.1 4.3e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KZN88540.1 - 1.8e-36 125.4 0.0 2.6e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 KZN88541.1 - 2.9e-19 68.8 0.1 1.7e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Apc13p protein APH PF01636.18 KZN88542.1 - 5.1e-11 42.7 1.4 8e-11 42.1 0.8 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN88542.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN88542.1 - 0.032 13.3 0.0 0.69 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.15 KZN88542.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase IF-2B PF01008.12 KZN88543.1 - 9.6e-75 251.1 0.0 1.3e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.18 KZN88544.1 - 6.4e-113 376.8 0.0 9.8e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF1460 PF07313.7 KZN88544.1 - 0.11 11.7 1.5 0.19 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF87 PF01935.12 KZN88544.1 - 0.14 11.9 3.5 0.72 9.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KZN88544.1 - 1.4 6.6 7.0 2.2 6.0 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Extensin_2 PF04554.8 KZN88545.1 - 0.01 15.6 2.1 0.024 14.5 1.4 1.6 1 0 0 1 1 1 0 Extensin-like region DUF1275 PF06912.6 KZN88546.1 - 1.3e-46 158.4 14.1 1.6e-46 158.1 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.6 KZN88546.1 - 0.095 12.4 5.4 0.15 11.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) UPF0154 PF03672.8 KZN88546.1 - 0.16 11.5 0.5 0.35 10.5 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF3953 PF13129.1 KZN88546.1 - 3.7 7.2 0.0 3.6 7.3 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3953) Macro_2 PF14519.1 KZN88548.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Ion_trans_2 PF07885.11 KZN88549.1 - 3.4e-29 100.3 19.1 6.5e-17 61.0 3.9 3.3 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.26 KZN88549.1 - 0.03 13.5 20.3 0.14 11.3 1.1 3.8 3 2 0 3 3 3 0 Ion transport protein Fungal_trans_2 PF11951.3 KZN88551.1 - 8.5e-51 172.7 0.0 1.8e-50 171.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88551.1 - 2e-05 24.4 5.9 4.1e-05 23.4 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans3 PF11051.3 KZN88552.1 - 8.1e-75 251.6 0.0 2.5e-74 250.0 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative 3-PAP PF12578.3 KZN88553.1 - 0.1 12.4 0.8 0.17 11.7 0.6 1.3 1 0 0 1 1 1 0 Myotubularin-associated protein CMD PF02627.15 KZN88554.1 - 0.064 13.0 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family BCIP PF13862.1 KZN88555.1 - 1.9e-74 249.4 0.1 2.4e-74 249.0 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 KZN88556.1 - 1.6e-09 37.7 0.0 3.2e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 KZN88557.1 - 5.3e-37 124.3 9.5 1.3e-09 37.5 0.6 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KZN88557.1 - 6.6e-05 21.2 9.0 0.061 11.4 0.2 4.2 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Sad1_UNC PF07738.8 KZN88558.1 - 1.8e-10 40.7 0.0 1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal SRR1 PF07985.7 KZN88559.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 LCM PF04072.9 KZN88559.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase CBS PF00571.23 KZN88562.1 - 1.7e-29 101.2 3.4 3.1e-11 42.8 0.0 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 KZN88562.1 - 0.087 12.7 0.9 4.2 7.3 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RhoGAP PF00620.22 KZN88563.1 - 0.0092 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.19 KZN88564.1 - 1.2e-106 357.0 14.6 1.3e-106 356.8 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88564.1 - 6.3e-23 81.0 20.2 6.3e-23 81.0 14.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.18 KZN88565.1 - 1.2e-70 238.1 0.0 1.5e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KZN88565.1 - 0.067 13.4 0.1 1.7 8.9 0.1 2.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Fructosamin_kin PF03881.9 KZN88566.1 - 0.032 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Fungal_trans_2 PF11951.3 KZN88567.1 - 8.6e-13 47.6 0.3 3e-12 45.8 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88567.1 - 8.6e-10 38.3 6.8 1.7e-09 37.4 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 KZN88567.1 - 0.01 15.6 1.2 0.022 14.5 0.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) FPN1 PF06963.7 KZN88568.1 - 5.4e-156 519.3 26.6 6.3e-156 519.0 18.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) ECH_C PF13766.1 KZN88569.1 - 7.5e-40 135.7 0.0 1.8e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KZN88569.1 - 2.6e-25 88.9 0.0 1.8e-24 86.2 0.0 1.9 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 KZN88570.1 - 1.5e-44 151.7 0.0 2.1e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 KZN88571.1 - 5.5e-13 49.0 0.0 8.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S26 PF10502.4 KZN88572.1 - 1.3e-06 27.9 0.0 0.00037 20.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KZN88572.1 - 0.00011 21.7 0.1 0.00024 20.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like DUF1264 PF06884.6 KZN88573.1 - 2.5e-76 254.8 0.0 2.9e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Acetyltransf_4 PF13420.1 KZN88575.1 - 1.9e-05 24.6 0.1 3.5e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN88575.1 - 2.2e-05 24.6 0.0 3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN88575.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Imm42 PF15601.1 KZN88576.1 - 0.028 13.8 0.2 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 42 adh_short PF00106.20 KZN88577.1 - 0.0006 19.7 0.1 0.0094 15.8 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase AP_endonuc_2 PF01261.19 KZN88578.1 - 0.0029 16.9 0.0 0.0083 15.4 0.0 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel ADH_N PF08240.7 KZN88579.1 - 3.6e-25 87.8 0.1 9e-25 86.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88579.1 - 3.9e-09 36.1 0.1 8.6e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KZN88579.1 - 5.7e-06 25.8 0.3 1.3e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 KZN88579.1 - 0.002 16.7 0.2 0.0052 15.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN88579.1 - 0.0077 15.1 0.5 0.015 14.1 0.2 1.5 1 1 1 2 2 2 1 FAD binding domain Methyltransf_18 PF12847.2 KZN88579.1 - 0.011 16.3 0.2 0.045 14.3 0.1 2.2 2 1 0 2 2 1 0 Methyltransferase domain TrkA_N PF02254.13 KZN88579.1 - 0.012 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KZN88579.1 - 0.015 15.7 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KZN88579.1 - 0.015 14.1 0.1 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 KZN88579.1 - 0.023 14.7 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 KZN88579.1 - 0.039 13.5 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KZN88579.1 - 0.044 13.8 0.2 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KZN88579.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KZN88579.1 - 0.059 13.4 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KZN88579.1 - 0.065 13.6 0.1 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LRR_3 PF07725.7 KZN88580.1 - 0.24 11.2 0.8 0.63 9.9 0.6 1.8 1 0 0 1 1 1 0 Leucine Rich Repeat Pkinase PF00069.20 KZN88581.1 - 1.1e-25 90.2 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88581.1 - 2.2e-07 30.2 0.0 3.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN88581.1 - 0.11 12.2 0.6 0.26 10.9 0.4 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4483 PF14825.1 KZN88582.1 - 0.05 13.2 0.2 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Las1 PF04031.8 KZN88583.1 - 1.2e-43 148.4 0.0 1.9e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 KZN88583.1 - 4.1e-29 101.6 0.4 6.6e-29 100.9 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN88583.1 - 0.00019 21.0 0.1 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KZN88583.1 - 0.016 14.5 0.1 0.033 13.4 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family NAD_kinase PF01513.16 KZN88584.1 - 6.6e-68 228.5 0.0 9.9e-68 227.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase L_biotic_typeA PF04604.8 KZN88584.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Type-A lantibiotic TRAPP PF04051.11 KZN88585.1 - 1.3e-36 125.4 0.0 1.6e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 KZN88586.1 - 4.5e-44 150.7 33.1 4.5e-44 150.7 23.0 2.4 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain Rep_fac-A_3 PF08661.6 KZN88587.1 - 2e-27 95.2 0.0 2.4e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 KZN88587.1 - 0.0024 17.6 0.2 0.029 14.1 0.1 2.0 1 1 0 1 1 1 1 Telomere capping, CST complex subunit GATA PF00320.22 KZN88588.1 - 8.1e-05 21.8 3.0 0.003 16.8 0.7 2.7 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 KZN88589.1 - 3.3e-19 68.2 0.1 4.5e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Lyase_1 PF00206.15 KZN88589.1 - 0.028 13.5 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Lyase Dak1 PF02733.12 KZN88590.1 - 7.1e-110 366.6 0.3 1e-109 366.0 0.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KZN88590.1 - 9e-44 149.2 0.2 1.5e-43 148.4 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.17 KZN88591.1 - 9.3e-129 430.6 0.0 1.1e-128 430.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KZN88591.1 - 1.6e-25 88.6 0.5 5e-25 87.1 0.3 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 KZN88591.1 - 0.00025 20.8 0.0 0.00078 19.3 0.0 1.8 1 1 0 1 1 1 1 HbrB-like HTH_34 PF13601.1 KZN88591.1 - 0.068 13.2 0.0 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain Peptidase_C48 PF02902.14 KZN88592.1 - 4.1e-15 55.9 0.3 3.1e-14 53.1 0.2 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.13 KZN88593.1 - 1.2e-05 25.0 3.1 4.9e-05 23.1 2.2 2.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TarH PF02203.10 KZN88593.1 - 0.18 11.6 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue RhoGEF PF00621.15 KZN88595.1 - 3.6e-36 124.7 0.0 6.8e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 KZN88595.1 - 2.2e-12 46.9 2.8 2.7e-12 46.6 0.4 2.3 2 1 1 3 3 3 1 BAR domain SH3_2 PF07653.12 KZN88595.1 - 0.089 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain Telomerase_RBD PF12009.3 KZN88596.1 - 1.1e-44 151.5 1.2 2.6e-44 150.4 0.9 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KZN88596.1 - 1.8e-14 53.6 0.0 5.1e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.13 KZN88597.1 - 1.3e-29 103.2 0.1 3.4e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain E1-E2_ATPase PF00122.15 KZN88598.1 - 1.6e-48 164.7 4.2 1.6e-48 164.7 2.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN88598.1 - 4.6e-42 143.5 4.0 4.6e-42 143.5 2.8 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN88598.1 - 1e-31 111.0 0.0 3.4e-31 109.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN88598.1 - 2.7e-20 72.0 0.0 5.3e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN88598.1 - 7.8e-13 49.0 0.0 1.9e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN88598.1 - 1.5e-10 40.4 0.0 3.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN88598.1 - 6.2e-05 22.7 0.1 0.00035 20.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KZN88599.1 - 2.7e-31 108.6 0.0 1.3e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88599.1 - 1.5e-14 53.7 0.0 3.2e-14 52.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN88599.1 - 0.052 12.5 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.20 KZN88600.1 - 1.5e-22 80.3 0.9 5.6e-22 78.4 0.6 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88600.1 - 7e-18 65.2 0.5 2e-17 63.7 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88600.1 - 1.4e-09 37.8 0.5 2.8e-09 36.9 0.3 1.6 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KZN88600.1 - 0.0026 17.8 0.2 0.0057 16.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 KZN88600.1 - 0.0027 16.8 0.1 0.0045 16.1 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KZN88600.1 - 0.015 14.7 0.5 0.082 12.3 0.1 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN88600.1 - 0.016 15.1 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding ADH_zinc_N PF00107.21 KZN88601.1 - 3e-22 78.5 0.1 5.9e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88601.1 - 3.2e-07 31.2 0.0 8e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3806 PF12713.2 KZN88601.1 - 0.026 14.0 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) DUF506 PF04720.7 KZN88601.1 - 0.12 11.9 0.0 0.47 10.0 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF506) Abhydrolase_6 PF12697.2 KZN88603.1 - 2.9e-08 33.8 1.2 1.7e-06 28.0 0.2 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN88603.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 KZN88603.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KZN88603.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_S28e PF01200.13 KZN88604.1 - 5.3e-34 115.7 2.2 5.8e-34 115.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 KZN88605.1 - 2e-90 302.3 0.0 3.4e-90 301.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN88605.1 - 1.6e-38 132.5 1.5 2.2e-38 132.0 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KZN88605.1 - 2.5e-28 98.3 0.0 7.2e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KZN88605.1 - 2.8e-08 33.8 0.0 9.6e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KZN88605.1 - 4.4e-06 26.7 0.0 1.5e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV ORC6 PF05460.8 KZN88605.1 - 1.8 7.5 17.3 3.3 6.7 12.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Prenyltrans PF00432.16 KZN88606.1 - 1.9e-53 177.6 7.6 1.7e-11 43.4 0.1 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KZN88606.1 - 7.4e-34 116.5 0.3 1.1e-12 48.3 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KZN88606.1 - 3.7e-12 46.2 0.0 9.3e-05 22.4 0.0 3.8 2 1 1 3 3 3 2 Prenyltransferase-like RhoGAP PF00620.22 KZN88607.1 - 1.6e-27 95.9 0.0 2.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 KZN88608.1 - 3.8e-60 202.0 3.9 4.8e-60 201.7 2.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 KZN88609.1 - 1.7e-97 326.0 0.0 2.1e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 KZN88609.1 - 0.0036 16.2 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Aldo_ket_red PF00248.16 KZN88610.1 - 9.8e-62 208.3 0.0 1.1e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 KZN88610.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like CAMP_factor PF07373.6 KZN88610.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 CAMP factor (Cfa) Arylsulfotran_2 PF14269.1 KZN88611.1 - 2.5e-44 151.6 0.1 3.7e-44 151.0 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN88611.1 - 3.9e-12 45.4 1.9 6e-11 41.5 1.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3405 PF11885.3 KZN88612.1 - 1.6e-160 534.6 8.6 2.9e-159 530.4 6.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) KRBA1 PF15287.1 KZN88612.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 KRBA1 family repeat SET PF00856.23 KZN88613.1 - 3e-09 37.3 0.0 1.2e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 KZN88613.1 - 6.2e-08 32.1 0.3 1.4e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 KZN88613.1 - 1.7e-06 27.3 0.0 3.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain TPR_17 PF13431.1 KZN88613.1 - 0.00079 19.4 0.1 0.0025 17.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88613.1 - 0.0011 19.5 0.0 0.0036 17.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN88613.1 - 0.012 15.1 0.4 0.8 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN88613.1 - 0.052 13.4 0.3 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.7 KZN88613.1 - 0.16 12.3 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 SAF domain DUF4414 PF14377.1 KZN88615.1 - 0.038 13.8 0.6 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Daxx PF03344.10 KZN88615.1 - 0.17 10.3 6.8 0.24 9.8 4.7 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KZN88615.1 - 4.2 6.3 11.0 6.4 5.7 7.7 1.2 1 0 0 1 1 1 0 BUD22 NRN1 PF15056.1 KZN88616.1 - 0.02 14.8 0.6 0.02 14.8 0.4 2.1 3 0 0 3 3 3 0 Neuritin protein family ADH_N PF08240.7 KZN88617.1 - 6.5e-26 90.2 0.7 1.1e-25 89.5 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88617.1 - 7.4e-22 77.2 0.3 1.1e-21 76.7 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88617.1 - 0.05 14.4 0.2 0.1 13.5 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TAN PF11640.3 KZN88619.1 - 4.5e-47 159.6 0.9 1.8e-46 157.7 0.4 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 KZN88619.1 - 3.1e-45 154.4 0.7 8e-45 153.1 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KZN88619.1 - 3e-10 39.3 0.1 7.2e-10 38.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain DUF4015 PF13200.1 KZN88619.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain DUF3414 PF11894.3 KZN88620.1 - 0 1480.0 12.5 0 1479.7 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) SLX9 PF15341.1 KZN88621.1 - 0.13 12.7 1.3 15 6.0 0.1 2.7 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Cyclin PF08613.6 KZN88623.1 - 1.1e-37 129.7 1.2 2.6e-22 79.8 0.3 2.6 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 KZN88624.1 - 8.3e-44 149.1 0.0 9.4e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_5 PF12695.2 KZN88625.1 - 2.7e-22 79.1 0.0 4.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN88625.1 - 9.8e-19 68.1 0.0 1.7e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN88625.1 - 6.9e-06 25.4 0.0 2.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 KZN88625.1 - 0.00016 20.5 0.0 0.00023 20.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.7 KZN88625.1 - 0.00022 19.8 0.0 0.24 9.8 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KZN88625.1 - 0.00027 20.7 0.0 0.039 13.6 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KZN88625.1 - 0.00074 19.0 0.0 0.0035 16.8 0.0 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KZN88625.1 - 0.0054 16.2 0.0 0.46 9.9 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KZN88625.1 - 0.01 15.1 0.0 0.97 8.6 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.8 KZN88625.1 - 0.014 14.9 0.0 0.13 11.8 0.0 2.3 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 KZN88625.1 - 0.015 14.8 0.0 0.84 9.1 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KZN88625.1 - 0.033 13.7 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KZN88625.1 - 0.082 12.3 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Putative esterase DUF2305 PF10230.4 KZN88625.1 - 0.1 11.9 0.0 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KZN88625.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 KZN88625.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ATP11 PF06644.6 KZN88626.1 - 4.2e-87 292.0 0.0 4.9e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF1880 PF08976.6 KZN88626.1 - 0.0071 16.4 0.4 0.013 15.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1880) zf-C4H2 PF10146.4 KZN88626.1 - 0.019 14.9 2.7 0.019 14.9 1.9 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4168 PF13767.1 KZN88626.1 - 0.14 12.8 0.5 1.8 9.2 0.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Cupin_7 PF12973.2 KZN88627.1 - 2.3e-07 30.5 0.0 2.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain R3H PF01424.17 KZN88628.1 - 8.6e-10 38.1 0.0 2.2e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KZN88628.1 - 2.6e-05 24.0 30.7 0.0003 20.6 7.6 14.0 13 2 0 13 13 13 7 NF-X1 type zinc finger Rpp20 PF12328.3 KZN88628.1 - 0.41 10.2 3.8 1.2 8.7 2.6 1.7 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P zf-LYAR PF08790.6 KZN88629.1 - 1.3e-14 53.5 4.5 2.7e-14 52.5 3.1 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Eapp_C PF10238.4 KZN88629.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.4 3 0 0 3 3 3 0 E2F-associated phosphoprotein Evr1_Alr PF04777.8 KZN88630.1 - 1e-20 73.3 1.7 6.2e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 Erv1 / Alr family Glyco_hydro_92 PF07971.7 KZN88631.1 - 4.3e-172 573.2 0.2 5.6e-172 572.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 GP41 PF00517.12 KZN88632.1 - 0.036 13.6 0.3 0.051 13.1 0.2 1.1 1 0 0 1 1 1 0 Retroviral envelope protein T2SJ PF11612.3 KZN88632.1 - 0.045 13.4 0.1 0.076 12.7 0.0 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J GvpL_GvpF PF06386.6 KZN88632.1 - 0.067 12.7 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FAM91_C PF14648.1 KZN88632.1 - 0.072 11.9 0.2 0.088 11.6 0.1 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Aldo_ket_red PF00248.16 KZN88634.1 - 2.3e-62 210.3 0.0 2.8e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KZN88635.1 - 3.9e-19 68.5 56.6 1.6e-14 53.3 22.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN88635.1 - 0.00071 17.9 7.7 0.0013 17.0 5.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KZN88636.1 - 3e-50 170.9 36.0 3e-50 170.9 25.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88636.1 - 1.6e-09 36.8 13.6 1.6e-09 36.8 9.4 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter PAP_PilO PF06864.7 KZN88636.1 - 0.15 10.4 0.0 0.26 9.6 0.0 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Bacteriocin_IIc PF10439.4 KZN88636.1 - 4 7.6 11.0 0.93 9.6 3.4 2.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide MBOAT_2 PF13813.1 KZN88638.1 - 1.1e-19 70.3 2.1 4.3e-19 68.3 1.4 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.3 KZN88641.1 - 0.00011 21.0 3.1 0.001 17.7 1.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88641.1 - 0.001 18.9 4.1 0.0016 18.2 2.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 KZN88642.1 - 6.6e-160 532.9 0.1 7.6e-160 532.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Git3 PF11710.3 KZN88644.1 - 3e-32 111.8 15.1 3e-32 111.8 10.5 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KZN88644.1 - 2e-13 49.9 0.0 5.5e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KZN88644.1 - 1.3e-07 30.9 11.2 1.3e-07 30.9 7.8 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 KZN88644.1 - 0.00014 20.8 17.5 0.00024 20.0 11.9 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.6 KZN88644.1 - 0.063 13.0 0.1 0.063 13.0 0.1 2.4 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Fungal_lectin PF07938.7 KZN88645.1 - 6e-80 268.8 3.4 6.7e-80 268.6 2.4 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin Xlink PF00193.12 KZN88645.1 - 0.047 13.7 0.1 0.97 9.5 0.0 2.4 2 0 0 2 2 2 0 Extracellular link domain Alkyl_sulf_dimr PF14863.1 KZN88645.1 - 0.057 13.6 0.3 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Aldo_ket_red PF00248.16 KZN88646.1 - 4.1e-64 216.1 0.0 4.7e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AHH PF14412.1 KZN88646.1 - 0.029 14.3 0.3 0.061 13.3 0.0 1.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Methyltransf_15 PF09445.5 KZN88646.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Fungal_trans_2 PF11951.3 KZN88647.1 - 1.2e-27 96.5 8.4 1.7e-15 56.5 0.4 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88647.1 - 0.00023 21.0 11.6 0.00041 20.2 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KZN88648.1 - 6.1e-42 143.6 42.9 3.3e-34 118.1 20.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KZN88648.1 - 2.8e-18 65.5 38.8 1.5e-16 59.8 26.9 2.0 1 1 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KZN88648.1 - 0.052 13.3 2.5 0.085 12.6 0.0 2.8 2 0 0 2 2 2 0 Gram positive anchor Amino_oxidase PF01593.19 KZN88649.1 - 4.5e-50 171.0 0.3 5.3e-50 170.7 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN88649.1 - 2.3e-14 53.1 0.1 4.5e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN88649.1 - 6.4e-11 41.7 0.0 5.4e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN88649.1 - 1.3e-08 34.1 0.2 2.4e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KZN88649.1 - 1.7e-06 27.4 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN88649.1 - 2.3e-06 26.7 0.3 3.6e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN88649.1 - 7.8e-06 26.0 0.4 0.0049 16.9 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN88649.1 - 3.1e-05 24.2 0.0 8.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN88649.1 - 4.8e-05 22.0 0.0 9.6e-05 21.0 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KZN88649.1 - 5.7e-05 22.3 0.3 9e-05 21.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KZN88649.1 - 8.7e-05 21.5 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN88649.1 - 0.00025 20.0 0.0 0.00064 18.7 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN88649.1 - 0.00032 20.6 0.2 0.00077 19.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN88649.1 - 0.0046 16.7 0.1 0.44 10.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Fungal_trans PF04082.13 KZN88650.1 - 3.4e-26 91.6 0.3 6.7e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88650.1 - 6.5e-09 35.5 10.1 1.7e-08 34.2 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2614 PF11023.3 KZN88650.1 - 0.35 10.6 1.0 0.74 9.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Mito_carr PF00153.22 KZN88651.1 - 2e-53 178.0 0.9 3.7e-17 61.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Hexokinase_2 PF03727.11 KZN88651.1 - 0.11 11.6 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Hexokinase Acyl-CoA_dh_1 PF00441.19 KZN88652.1 - 1.1e-28 100.2 0.5 1.6e-28 99.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN88652.1 - 1.4e-18 66.0 0.9 2.5e-18 65.3 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KZN88652.1 - 1.9e-17 63.8 0.0 3e-16 59.9 0.0 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KZN88652.1 - 0.00092 19.4 0.2 0.0014 18.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KZN88652.1 - 0.097 12.0 1.2 0.19 11.0 0.4 1.8 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DAGAT PF03982.8 KZN88652.1 - 0.15 10.7 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase CPSase_L_D2 PF02786.12 KZN88653.1 - 2.2e-69 232.9 0.1 3.9e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KZN88653.1 - 1e-35 122.1 0.2 4.6e-35 120.0 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KZN88653.1 - 3e-32 110.7 0.0 7.3e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KZN88653.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KZN88653.1 - 6.7e-11 41.9 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 KZN88653.1 - 9.8e-11 41.1 1.2 2.2e-10 39.9 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KZN88653.1 - 3.4e-10 39.1 0.0 6.5e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KZN88653.1 - 5.2e-10 38.9 0.3 2.7e-09 36.5 0.1 2.2 1 1 1 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KZN88653.1 - 3.6e-06 26.9 0.0 6.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KZN88653.1 - 6.4e-06 25.7 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.14 KZN88653.1 - 0.024 14.3 0.2 0.31 10.7 0.2 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF3182 PF11379.3 KZN88653.1 - 0.033 12.8 0.1 0.1 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) Carboxyl_trans PF01039.17 KZN88654.1 - 2.3e-116 389.0 0.0 2.7e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.23 KZN88655.1 - 8e-88 294.6 0.0 9.5e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN88655.1 - 8.7e-12 45.8 0.0 1.9e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L7Ae PF01248.21 KZN88655.1 - 0.029 13.8 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HMGL-like PF00682.14 KZN88656.1 - 4.2e-41 141.1 0.0 5.7e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 KZN88656.1 - 2.4e-37 128.4 0.0 3.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FAD_binding_4 PF01565.18 KZN88657.1 - 3.1e-21 75.3 2.2 6.1e-21 74.3 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN88658.1 - 2.3e-09 36.9 0.1 3.2e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KZN88658.1 - 0.013 14.6 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_76 PF03663.9 KZN88659.1 - 5.5e-47 160.9 10.0 9.5e-47 160.1 6.9 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KZN88659.1 - 0.0014 17.7 0.1 0.16 10.9 0.0 2.3 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.15 KZN88659.1 - 0.084 11.5 0.0 0.29 9.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 BetaGal_dom2 PF10435.4 KZN88660.1 - 1.4e-37 128.8 0.0 2.1e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KZN88660.1 - 1.2e-15 56.6 0.2 2.4e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 GST_N PF02798.15 KZN88661.1 - 6.7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN88661.1 - 2.9e-06 27.1 0.0 5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KZN88661.1 - 2.8e-05 24.2 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN88661.1 - 0.00035 20.4 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN88661.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.22 KZN88662.1 - 3.9e-18 65.7 0.1 5.5e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-CCCH PF00642.19 KZN88663.1 - 0.0039 16.8 1.4 0.0039 16.8 1.0 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GrpB PF04229.9 KZN88663.1 - 0.094 12.4 0.6 0.17 11.6 0.4 1.3 1 0 0 1 1 1 0 GrpB protein IncA PF04156.9 KZN88663.1 - 0.2 11.2 3.4 0.33 10.5 2.3 1.3 1 0 0 1 1 1 0 IncA protein APH PF01636.18 KZN88664.1 - 3e-17 63.1 0.1 5.7e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN88664.1 - 0.00048 19.7 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase NDUF_B5 PF09781.4 KZN88664.1 - 0.042 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit RIO1 PF01163.17 KZN88664.1 - 0.098 11.9 0.1 3.2 7.0 0.0 2.7 3 0 0 3 3 3 0 RIO1 family F-box-like PF12937.2 KZN88665.1 - 3e-10 39.6 0.1 1.1e-09 37.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN88665.1 - 4.1e-05 23.1 0.0 0.00017 21.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain UNC-50 PF05216.8 KZN88666.1 - 0.023 13.8 2.9 0.059 12.5 2.0 1.7 1 0 0 1 1 1 0 UNC-50 family Beta-lactamase PF00144.19 KZN88667.1 - 1.4e-57 195.2 0.0 1.6e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Xan_ur_permease PF00860.15 KZN88668.1 - 6.2e-23 80.9 34.0 9.7e-22 76.9 21.9 2.5 2 1 0 2 2 2 1 Permease family MFS_1 PF07690.11 KZN88669.1 - 1.4e-35 122.7 44.9 1.4e-35 122.7 31.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88669.1 - 1e-11 44.1 15.2 1e-11 44.1 10.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Podoplanin PF05808.6 KZN88671.1 - 5.5e-05 22.7 3.9 0.00011 21.7 2.7 1.5 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 KZN88671.1 - 0.0011 18.7 0.4 0.0016 18.1 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 KZN88671.1 - 0.0017 18.0 0.1 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Glycophorin_A PF01102.13 KZN88671.1 - 0.0027 17.4 8.3 0.0038 16.9 4.9 1.8 1 1 1 2 2 2 1 Glycophorin A Mid2 PF04478.7 KZN88671.1 - 0.004 16.5 0.6 0.004 16.5 0.4 2.2 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 KZN88671.1 - 0.011 15.0 1.0 0.032 13.5 0.7 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 KZN88671.1 - 0.013 14.9 0.1 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TrbL PF04610.9 KZN88671.1 - 0.059 13.0 4.0 0.084 12.5 2.8 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF2668 PF10873.3 KZN88671.1 - 0.062 13.4 0.2 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) EphA2_TM PF14575.1 KZN88671.1 - 0.079 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KZN88671.1 - 0.15 11.7 4.2 0.057 13.0 1.0 1.7 2 0 0 2 2 2 0 Syndecan domain Adeno_E3_CR2 PF02439.10 KZN88671.1 - 0.48 10.0 5.6 1 8.9 3.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 gpUL132 PF11359.3 KZN88671.1 - 0.78 9.0 8.3 1.1 8.4 5.8 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 DUF515 PF04415.7 KZN88671.1 - 0.98 7.5 8.3 1.4 7.0 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med3 PF11593.3 KZN88671.1 - 1.1 8.4 10.5 1.5 7.9 7.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Protocadherin PF08374.6 KZN88671.1 - 2.2 7.8 7.1 0.14 11.7 1.1 1.8 1 1 1 2 2 2 0 Protocadherin Macoilin PF09726.4 KZN88671.1 - 3.2 5.9 6.4 3.8 5.6 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Shisa PF13908.1 KZN88671.1 - 3.5 7.7 11.8 0.16 12.1 1.6 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Folate_carrier PF01770.13 KZN88672.1 - 0.098 11.1 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Sugar_tr PF00083.19 KZN88674.1 - 4e-123 411.3 25.0 4.5e-123 411.1 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88674.1 - 5.9e-25 87.7 36.5 2.6e-21 75.7 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2781 PF10914.3 KZN88674.1 - 0.09 12.5 1.4 0.51 10.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) ThiF PF00899.16 KZN88675.1 - 8.3e-43 145.4 0.0 1.3e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KZN88675.1 - 3.1e-23 81.1 0.1 7.2e-23 79.9 0.1 1.6 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KZN88675.1 - 6e-08 33.0 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KZN88675.1 - 0.00064 19.8 0.1 0.0018 18.3 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF4407 PF14362.1 KZN88675.1 - 0.012 14.6 0.8 0.017 14.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_7 PF13241.1 KZN88675.1 - 0.033 14.4 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DPBB_1 PF03330.13 KZN88676.1 - 5.6e-06 26.2 0.1 1.2e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Toxin_45 PF15524.1 KZN88676.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 45 adh_short PF00106.20 KZN88678.1 - 4.6e-28 98.2 0.0 6.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN88678.1 - 1e-24 87.6 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN88678.1 - 6.8e-12 45.4 0.0 9.1e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KZN88678.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KZN88678.1 - 0.1 11.6 0.1 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abhydrolase_3 PF07859.8 KZN88679.1 - 4.8e-33 114.5 0.0 5.8e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN88679.1 - 8.3e-09 34.9 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KZN88679.1 - 0.00027 20.2 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 KZN88679.1 - 0.042 13.5 0.0 0.093 12.4 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2422 PF10337.4 KZN88680.1 - 3.5e-114 382.1 3.6 3.5e-114 382.1 2.5 4.2 3 2 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KZN88680.1 - 1.3e-14 54.3 0.0 4.2e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KZN88680.1 - 1.4e-14 54.0 17.3 1.4e-14 54.0 12.0 3.4 2 2 1 3 3 3 1 Fusaric acid resistance protein-like SnoaL_2 PF12680.2 KZN88681.1 - 0.00077 19.8 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KZN88681.1 - 0.049 13.8 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) p450 PF00067.17 KZN88682.1 - 3e-63 213.9 0.0 4e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KZN88683.1 - 7.2e-35 120.3 39.7 4.6e-34 117.6 21.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN88684.1 - 2.4e-25 89.0 51.4 2.4e-25 89.0 35.6 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88684.1 - 2.4e-08 33.0 14.3 2.4e-08 33.0 9.9 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.19 KZN88686.1 - 2.4e-81 273.6 17.8 2.7e-81 273.4 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88686.1 - 1.6e-33 115.9 40.6 1.1e-31 109.9 13.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KZN88686.1 - 0.00055 18.1 0.3 0.0011 17.1 0.2 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3624 PF12292.3 KZN88686.1 - 0.47 10.8 7.1 0.74 10.2 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) Pec_lyase_C PF00544.14 KZN88688.1 - 2.8e-22 79.2 4.6 5e-22 78.3 3.2 1.4 1 0 0 1 1 1 1 Pectate lyase Amidase PF01425.16 KZN88689.1 - 2.8e-70 237.3 0.7 2.3e-66 224.4 0.0 2.0 2 0 0 2 2 2 2 Amidase PepSY_TM_3 PF13706.1 KZN88690.1 - 0.26 10.7 3.8 0.77 9.2 0.4 2.8 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1908 PF08926.6 KZN88690.1 - 0.29 9.8 1.3 0.46 9.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) NmrA PF05368.8 KZN88692.1 - 2.8e-11 43.1 0.0 4.8e-11 42.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KZN88692.1 - 0.00016 21.3 0.0 0.003 17.2 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KZN88692.1 - 0.00064 19.6 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KZN88692.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN88692.1 - 0.043 12.7 1.2 2 7.2 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Epimerase PF01370.16 KZN88692.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Fer2_3 PF13085.1 KZN88693.1 - 5.9e-32 109.7 0.0 9.7e-32 109.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KZN88693.1 - 6.3e-10 39.2 5.3 6.3e-10 39.2 3.7 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KZN88693.1 - 6.5e-09 35.6 4.4 6.5e-09 35.6 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KZN88693.1 - 0.00018 21.6 3.6 0.038 14.2 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KZN88693.1 - 0.00034 20.3 4.2 0.00034 20.3 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KZN88693.1 - 0.0019 18.5 1.8 0.0019 18.5 1.3 2.7 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 KZN88693.1 - 0.0053 17.1 4.9 0.0053 17.1 3.4 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KZN88693.1 - 0.012 15.3 0.6 0.012 15.3 0.4 2.2 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 KZN88693.1 - 1 9.9 5.6 0.92 10.1 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain p450 PF00067.17 KZN88694.1 - 2.8e-58 197.5 0.0 3.6e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F_bP_aldolase PF01116.15 KZN88696.1 - 8.1e-84 281.1 0.0 9e-84 280.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 KZN88696.1 - 0.05 12.6 0.1 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family NAD_binding_2 PF03446.10 KZN88697.1 - 1.6e-38 132.1 0.2 3.8e-38 130.8 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN88697.1 - 6.5e-38 129.5 3.9 4.8e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KZN88697.1 - 3.5e-05 24.1 0.2 0.00034 21.0 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KZN88697.1 - 0.00021 20.9 0.1 0.00053 19.6 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN88697.1 - 0.0053 15.9 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RGS PF00615.14 KZN88698.1 - 0.00013 22.0 0.0 0.00054 20.0 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain MethyTransf_Reg PF10119.4 KZN88700.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain zf-LITAF-like PF10601.4 KZN88701.1 - 9.8e-24 83.0 11.1 1.4e-23 82.4 7.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Ank_2 PF12796.2 KZN88702.1 - 2.8e-53 178.2 1.4 2.4e-15 56.6 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN88702.1 - 1.5e-42 141.3 3.1 1.7e-06 27.5 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KZN88702.1 - 1.5e-27 92.8 0.3 0.0024 17.9 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KZN88702.1 - 3.7e-27 93.7 11.7 6.1e-06 26.3 0.0 6.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN88702.1 - 2.5e-26 91.5 0.5 1.2e-07 32.0 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Pkinase PF00069.20 KZN88704.1 - 4.3e-11 42.4 0.0 1.3e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Alpha-amylase_C PF02806.13 KZN88705.1 - 1.7e-23 82.5 0.0 4.6e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KZN88705.1 - 3e-17 63.0 0.2 2.7e-13 50.0 0.1 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KZN88705.1 - 1.8e-16 59.9 0.1 4e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ATP-synt_ab PF00006.20 KZN88706.1 - 4.6e-62 209.3 0.0 7.3e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KZN88706.1 - 5.6e-25 88.0 0.5 1e-24 87.1 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KZN88706.1 - 2.3e-24 85.3 1.8 1.8e-23 82.4 0.8 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 KZN88706.1 - 0.0027 16.8 0.1 0.0046 16.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KZN88706.1 - 0.0075 15.6 0.1 0.036 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KZN88706.1 - 0.0088 16.2 0.0 0.88 9.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KZN88706.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 KZN88706.1 - 0.013 15.5 0.4 0.45 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KZN88706.1 - 0.018 14.7 0.1 1 9.0 0.0 3.0 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KZN88706.1 - 0.025 14.7 0.1 0.15 12.1 0.0 2.2 3 1 0 3 3 3 0 AAA domain NACHT PF05729.7 KZN88706.1 - 0.027 14.1 0.2 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 KZN88706.1 - 0.067 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KZN88706.1 - 0.075 11.8 0.5 0.29 9.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KZN88706.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase COX4 PF02936.9 KZN88707.1 - 4.7e-49 165.7 0.5 5.9e-49 165.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV GST_N_3 PF13417.1 KZN88708.1 - 1.4e-18 66.8 0.0 2.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN88708.1 - 2.3e-14 53.1 0.0 4.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN88708.1 - 4.2e-12 46.0 0.0 1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KZN88708.1 - 0.00035 20.4 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 KZN88708.1 - 0.00084 19.1 0.3 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Luciferase_cat PF10285.4 KZN88708.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain GST_C PF00043.20 KZN88708.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SH3_9 PF14604.1 KZN88709.1 - 1e-06 28.1 0.1 2.2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN88709.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Podoplanin PF05808.6 KZN88709.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Pmp3 PF01679.12 KZN88710.1 - 1e-19 69.9 6.7 1.3e-19 69.6 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GST_C_3 PF14497.1 KZN88711.1 - 9.4e-10 38.8 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN88711.1 - 4.6e-06 26.4 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN88711.1 - 0.0009 19.4 0.0 0.0049 17.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain She9_MDM33 PF05546.6 KZN88712.1 - 8.5e-94 312.9 11.1 1.4e-93 312.2 7.7 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 KZN88712.1 - 0.0034 16.9 0.7 0.0071 15.8 0.5 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Hanta_nucleocap PF00846.13 KZN88712.1 - 0.072 11.7 0.4 0.15 10.7 0.3 1.7 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein UCR_TM PF02921.9 KZN88713.1 - 3.8e-19 68.6 2.0 5.8e-19 68.0 0.7 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KZN88713.1 - 8.2e-17 60.5 0.0 1.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CBFD_NFYB_HMF PF00808.18 KZN88714.1 - 3.1e-15 55.9 0.4 3.1e-15 55.9 0.3 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 KZN88715.1 - 2.8e-89 299.6 30.3 2.8e-89 299.6 21.0 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KZN88715.1 - 2.6e-14 52.7 0.1 6.6e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain Sugar_tr PF00083.19 KZN88716.1 - 3.1e-69 233.7 21.0 3.6e-69 233.4 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88716.1 - 4.9e-22 78.1 33.0 3.6e-15 55.5 9.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN88716.1 - 0.00083 17.6 2.9 0.00083 17.6 2.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.9 KZN88717.1 - 1.9e-72 243.7 1.5 2.5e-72 243.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 KZN88717.1 - 0.033 12.9 0.0 0.084 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF377) F-box-like PF12937.2 KZN88718.1 - 0.0034 17.0 0.1 0.015 15.0 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN88718.1 - 0.053 13.1 1.1 0.34 10.6 0.0 2.8 3 0 0 3 3 3 0 F-box domain DUF3577 PF12101.3 KZN88719.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) FAD_binding_3 PF01494.14 KZN88720.1 - 2.6e-18 66.1 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KZN88720.1 - 9.8e-07 27.9 0.9 1.8e-06 27.0 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KZN88720.1 - 1.1e-06 28.5 0.3 2.5e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN88720.1 - 9.7e-06 24.7 5.0 0.0025 16.8 1.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN88720.1 - 2.7e-05 23.4 0.9 5.6e-05 22.3 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN88720.1 - 4.7e-05 23.7 1.5 0.00083 19.7 1.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN88720.1 - 0.00017 20.1 0.6 0.00072 18.1 0.5 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KZN88720.1 - 0.00024 21.0 0.4 0.00044 20.1 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN88720.1 - 0.00027 19.9 0.4 0.00055 18.9 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN88720.1 - 0.0015 17.5 0.2 0.32 9.8 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KZN88720.1 - 0.003 17.6 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN88720.1 - 0.036 13.1 0.8 0.087 11.9 0.2 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 KZN88720.1 - 0.21 11.2 0.7 0.37 10.4 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 KZN88720.1 - 0.3 9.2 0.5 0.46 8.6 0.3 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like EamA PF00892.15 KZN88721.1 - 3.5e-05 23.8 8.5 3.9e-05 23.6 5.2 1.6 1 1 1 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 KZN88721.1 - 0.0093 15.7 0.8 0.011 15.5 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 KZN88721.1 - 0.013 15.7 8.8 0.013 15.7 6.1 1.7 1 1 1 2 2 2 0 Multidrug resistance efflux transporter DUF2336 PF10098.4 KZN88721.1 - 0.044 13.0 0.1 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) CoA_transf_3 PF02515.12 KZN88721.1 - 0.084 12.1 0.7 0.54 9.4 0.0 2.1 2 1 0 2 2 2 0 CoA-transferase family III TPT PF03151.11 KZN88721.1 - 0.13 11.8 7.4 0.63 9.6 5.1 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family PNPOx_C PF10590.4 KZN88722.1 - 4.8e-20 70.7 7.1 1e-19 69.7 3.6 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KZN88722.1 - 1e-06 28.6 0.2 0.0025 17.8 0.0 3.1 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 KZN88723.1 - 1.8e-46 155.8 7.3 6.9e-10 38.7 0.0 13.4 11 4 5 16 16 16 10 PPR repeat family PPR_3 PF13812.1 KZN88723.1 - 4.4e-30 101.4 25.9 0.0017 18.4 0.0 15.6 16 0 0 16 16 16 7 Pentatricopeptide repeat domain PPR PF01535.15 KZN88723.1 - 7.2e-26 88.3 19.7 0.00043 20.0 0.0 13.7 14 2 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 KZN88723.1 - 1.6e-19 69.0 4.0 1.3e-06 27.7 0.0 10.1 12 0 0 12 12 12 3 PPR repeat RPM2 PF08579.6 KZN88723.1 - 8e-07 29.2 0.0 0.00053 20.1 0.0 4.3 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.1 KZN88723.1 - 1.3e-05 25.4 7.1 0.92 9.8 0.0 6.7 5 1 2 7 7 7 1 Tetratricopeptide repeat CHAD PF05235.9 KZN88723.1 - 0.0044 16.6 5.0 1.6 8.2 0.0 3.1 2 0 0 2 2 2 2 CHAD domain TPR_7 PF13176.1 KZN88723.1 - 0.25 11.2 6.0 2.6 8.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_11 PF08241.7 KZN88724.1 - 4.7e-23 81.4 0.0 1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88724.1 - 3.1e-18 65.7 0.0 5.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN88724.1 - 9.6e-16 57.9 0.1 2.3e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN88724.1 - 1.3e-15 57.5 0.1 4.1e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN88724.1 - 1.2e-12 48.0 0.0 2.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN88724.1 - 2e-12 46.7 0.0 2.7e-11 43.0 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KZN88724.1 - 7.1e-11 41.6 0.0 9.9e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KZN88724.1 - 1.6e-10 41.5 0.0 3.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN88724.1 - 2.6e-09 37.1 0.0 9.5e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN88724.1 - 1.3e-06 27.8 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KZN88724.1 - 1.7e-06 27.5 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 KZN88724.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 KZN88724.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 KZN88724.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KZN88724.1 - 0.0017 17.5 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KZN88724.1 - 0.0024 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KZN88724.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 KZN88724.1 - 0.0069 15.1 0.1 0.067 11.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PCMT PF01135.14 KZN88724.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 KZN88724.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 KZN88724.1 - 0.018 14.7 0.0 0.17 11.4 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.11 KZN88724.1 - 0.055 11.8 0.0 0.08 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.8 KZN88724.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 1 0 Histone methylation protein DOT1 GHMP_kinases_N PF00288.21 KZN88725.1 - 5.6e-14 51.9 1.7 1.6e-13 50.5 1.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KZN88725.1 - 1.3e-07 31.6 0.0 6.2e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 KZN88726.1 - 1e-11 44.6 0.0 2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KZN88726.1 - 0.00029 20.1 0.0 0.00054 19.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KZN88726.1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 KZN88727.1 - 4.3e-20 71.9 0.0 5.9e-20 71.5 0.0 1.3 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 KZN88728.1 - 3.5e-39 132.9 1.2 4.5e-39 132.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 KZN88729.1 - 9.9e-141 468.4 9.3 1.2e-140 468.1 6.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 KZN88730.1 - 1.9e-281 936.0 3.4 2.2e-281 935.8 2.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 KZN88731.1 - 7.6e-46 156.4 0.0 1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KZN88731.1 - 3.6e-25 87.6 0.2 6.3e-25 86.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KZN88731.1 - 2.4e-16 59.2 0.0 3.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN88731.1 - 4.3e-12 45.5 0.0 7.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN88731.1 - 2e-11 43.3 0.0 1.1e-09 37.6 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN88731.1 - 9.3e-10 38.7 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN88731.1 - 1.7e-09 37.8 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN88731.1 - 3.2e-07 30.1 0.0 5.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KZN88731.1 - 1.3e-06 27.5 0.0 4.3e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KZN88731.1 - 0.015 14.5 0.0 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Phage_lysozyme PF00959.14 KZN88731.1 - 0.033 14.4 0.1 0.73 10.1 0.0 2.4 2 0 0 2 2 2 0 Phage lysozyme UDPG_MGDP_dh_N PF03721.9 KZN88731.1 - 0.057 12.8 0.1 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.19 KZN88731.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KZN88732.1 - 8.2e-15 55.1 0.0 1.2e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN88732.1 - 3.9e-07 29.9 0.0 8.6e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN88732.1 - 8.3e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN88732.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KZN88732.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_4 PF13579.1 KZN88732.1 - 0.027 14.6 0.3 0.069 13.2 0.1 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain NmrA PF05368.8 KZN88732.1 - 0.043 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KZN88732.1 - 0.1 11.4 1.0 0.23 10.3 0.0 2.0 3 0 0 3 3 3 0 RmlD substrate binding domain E1-N PF14463.1 KZN88732.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain G-patch PF01585.18 KZN88733.1 - 4.2e-06 26.4 0.1 7.5e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Mito_fiss_reg PF05308.6 KZN88733.1 - 6.8 5.9 12.9 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Sec1 PF00995.18 KZN88734.1 - 6.2e-141 470.8 0.0 7.2e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.3 KZN88735.1 - 1.6e-16 59.4 0.1 4.1e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KZN88735.1 - 2.1e-09 37.1 0.0 4.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 KZN88736.1 - 1.4e-28 98.9 0.1 1.4e-28 98.9 0.1 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KZN88736.1 - 5.2e-26 90.7 0.0 3.2e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KZN88736.1 - 8.3e-12 44.7 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KZN88736.1 - 6.2e-11 42.2 0.6 1.2e-10 41.2 0.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KZN88736.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KZN88736.1 - 0.00015 20.8 0.0 0.00033 19.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KZN88736.1 - 0.00025 21.2 0.0 0.00065 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KZN88736.1 - 0.007 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KZN88736.1 - 0.049 12.7 0.1 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KZN88736.1 - 0.071 12.8 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KZN88736.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Npa1 PF11707.3 KZN88737.1 - 2.9e-98 328.9 0.0 9.4e-98 327.2 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal MFS_1 PF07690.11 KZN88738.1 - 3.5e-32 111.4 32.2 4.6e-32 111.1 22.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 KZN88739.1 - 0.00012 21.7 0.3 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN88739.1 - 0.00014 21.3 0.2 0.0013 18.3 0.0 2.5 1 1 1 2 2 2 1 F-box domain ADH_N PF08240.7 KZN88740.1 - 4.2e-28 97.2 2.5 7.9e-28 96.3 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88740.1 - 1.8e-18 66.3 0.5 8.6e-18 64.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88740.1 - 2e-07 31.9 0.0 3.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN88740.1 - 0.042 13.0 0.1 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.1 KZN88740.1 - 0.052 13.2 0.2 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Aa_trans PF01490.13 KZN88741.1 - 1.2e-55 188.7 39.1 1.3e-55 188.5 27.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 KZN88741.1 - 0.25 10.5 0.9 0.5 9.5 0.6 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 MFS_1 PF07690.11 KZN88743.1 - 2.3e-07 29.8 19.4 2.3e-07 29.8 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.4 KZN88745.1 - 6.1e-15 55.4 4.4 6.1e-15 55.4 3.1 3.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF572 PF04502.8 KZN88745.1 - 3.9 6.6 10.9 4.5 6.4 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Alpha-amylase PF00128.19 KZN88746.1 - 1.5e-56 192.0 0.0 2.2e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KZN88746.1 - 2.7e-22 78.6 0.6 5.1e-22 77.7 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Avirulence PF03377.8 KZN88746.1 - 0.15 10.7 0.0 0.65 8.6 0.0 1.8 2 0 0 2 2 2 0 Xanthomonas avirulence protein, Avr/PthA Alpha-amylase PF00128.19 KZN88747.1 - 9e-20 71.2 0.5 1.5e-17 63.9 0.4 3.1 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KZN88747.1 - 2.4e-15 56.6 0.1 4e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KZN88747.1 - 4.9e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KZN88747.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 KZN88747.1 - 0.1 13.2 0.4 0.26 11.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Ins_P5_2-kin PF06090.7 KZN88748.1 - 0.092 11.7 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DUF1772 PF08592.6 KZN88749.1 - 5.8e-19 68.2 0.5 8e-19 67.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pro_CA PF00484.14 KZN88750.1 - 4.3e-49 166.4 0.0 5.9e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF3824 PF12868.2 KZN88752.1 - 1.2e-14 55.4 7.1 1.2e-14 55.4 4.9 5.9 3 3 1 4 4 4 1 Domain of unknwon function (DUF3824) E1-E2_ATPase PF00122.15 KZN88753.1 - 6.7e-45 152.8 5.1 1.3e-44 151.9 3.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN88753.1 - 2.2e-26 93.5 0.1 3.6e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN88753.1 - 1.1e-13 51.8 0.0 3e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN88753.1 - 3.1e-06 27.2 0.5 2.4e-05 24.3 0.1 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KZN88753.1 - 1.2e-05 25.0 0.5 0.00088 18.9 0.1 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase SNF2_N PF00176.18 KZN88756.1 - 2.6e-51 174.1 0.0 4e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN88756.1 - 0.00052 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KZN88756.1 - 0.0016 18.0 1.8 0.0039 16.8 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88756.1 - 0.0063 16.5 4.3 0.018 15.0 3.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN88756.1 - 0.011 15.3 3.0 0.031 13.9 2.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN88756.1 - 0.047 13.4 3.9 0.12 12.0 2.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KZN88756.1 - 0.2 11.5 3.4 0.56 10.0 2.4 1.7 1 0 0 1 1 1 0 Ring finger domain SNF2_N PF00176.18 KZN88757.1 - 7.4e-50 169.4 0.1 1.3e-49 168.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN88757.1 - 4.2e-10 39.3 0.0 9.4e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KZN88757.1 - 4.2e-07 29.5 8.5 8.3e-07 28.6 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 KZN88757.1 - 2.4e-05 24.2 0.0 7.4e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN88757.1 - 0.0011 18.4 0.7 0.0067 15.9 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KZN88757.1 - 0.0018 18.0 7.9 0.0041 16.9 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain UPF0449 PF15136.1 KZN88757.1 - 0.016 15.4 0.2 0.043 14.0 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 zf-C3HC4_2 PF13923.1 KZN88757.1 - 0.027 14.4 6.9 0.072 13.1 4.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN88757.1 - 0.027 14.1 3.3 0.087 12.5 1.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KZN88757.1 - 0.51 10.0 7.9 1.3 8.7 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KZN88757.1 - 0.53 10.2 6.5 1.4 8.9 4.5 1.7 1 0 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 KZN88757.1 - 5.5 6.8 8.3 44 3.9 0.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon LRR_4 PF12799.2 KZN88758.1 - 0.084 12.5 0.8 0.32 10.6 0.2 2.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 KZN88758.1 - 0.15 12.0 1.7 11 6.0 0.7 2.6 2 0 0 2 2 2 0 FNIP Repeat DUF221 PF02714.10 KZN88759.1 - 2.3e-110 368.5 16.5 2.3e-110 368.5 11.5 2.8 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KZN88759.1 - 2.9e-42 143.9 5.5 2.9e-42 143.9 3.8 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KZN88759.1 - 8.1e-33 112.1 0.3 3.9e-32 109.9 0.1 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KZN88759.1 - 1.3e-21 76.8 0.3 2.2e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ODV-E18 PF10717.4 KZN88759.1 - 0.47 9.9 13.0 0.88 9.0 1.1 3.6 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF4519 PF15012.1 KZN88759.1 - 0.83 9.6 0.0 0.83 9.6 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4519) TraQ PF09679.5 KZN88759.1 - 2.6 8.0 5.3 4.8 7.1 0.0 3.6 4 0 0 4 4 4 0 Type-F conjugative transfer system pilin chaperone (TraQ) Transglut_core2 PF13369.1 KZN88760.1 - 0.04 13.3 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily MCM PF00493.18 KZN88762.1 - 9.1e-131 435.5 0.1 1.4e-130 434.9 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KZN88762.1 - 2e-15 57.3 1.6 3.9e-15 56.3 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN88762.1 - 4.2e-05 22.8 0.0 0.0002 20.5 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN88762.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KZN88762.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KZN88762.1 - 0.0081 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain NUT_N PF12881.2 KZN88763.1 - 0.0052 15.9 0.8 0.0094 15.1 0.6 1.6 1 1 0 1 1 1 1 NUT protein N terminus DUF2360 PF10152.4 KZN88763.1 - 3 8.1 7.9 0.75 10.0 1.6 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pyridox_oxase_2 PF12766.2 KZN88765.1 - 6.1e-29 100.2 0.0 1.3e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Terpene_synth_C PF03936.11 KZN88766.1 - 3.1e-07 29.8 0.2 5e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4508 PF14969.1 KZN88766.1 - 0.12 12.4 0.6 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) DUF3716 PF12511.3 KZN88767.1 - 4.6e-14 51.7 5.0 6.8e-14 51.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AMP-binding PF00501.23 KZN88768.1 - 0 1440.6 4.1 3.1e-85 286.0 0.0 7.3 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KZN88768.1 - 0 1014.4 7.3 1.6e-50 171.6 0.0 8.5 8 0 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KZN88768.1 - 9.4e-77 253.2 4.0 2e-11 43.9 0.0 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN88768.1 - 2.2e-26 92.5 3.0 9.7e-05 23.2 0.0 6.6 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain AATase PF07247.7 KZN88768.1 - 1.2e-05 24.0 0.0 0.075 11.5 0.0 3.2 4 0 0 4 4 4 2 Alcohol acetyltransferase Transferase PF02458.10 KZN88768.1 - 0.013 13.9 0.1 34 2.6 0.0 4.0 4 0 0 4 4 4 0 Transferase family GNAT_acetyltran PF12746.2 KZN88768.1 - 3 6.6 0.0 5.7 5.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase CRAL_TRIO PF00650.15 KZN88768.1 - 3.4 7.1 0.0 7.3 6.0 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO domain GH3 PF03321.8 KZN88768.1 - 7.6 4.9 0.1 2.2e+02 0.0 0.0 2.9 5 0 0 5 5 5 0 GH3 auxin-responsive promoter DUF619 PF04768.8 KZN88769.1 - 5.4e-11 42.2 0.1 1.4e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 KZN88769.1 - 0.0024 17.4 0.0 0.04 13.4 0.0 2.3 1 1 0 1 1 1 1 Amino acid kinase family Tom7 PF08038.7 KZN88769.1 - 0.1 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 TOM7 family Ank_4 PF13637.1 KZN88770.1 - 1.2e-18 67.0 2.1 1.6e-11 44.3 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN88770.1 - 1.5e-18 65.5 6.6 1.8e-07 30.6 0.5 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KZN88770.1 - 8.1e-17 61.3 1.2 1.7e-16 60.2 0.8 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN88770.1 - 1.4e-15 56.9 2.3 2.7e-07 30.5 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN88770.1 - 1.5e-11 43.3 1.1 8.9e-05 22.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Aminotran_4 PF01063.14 KZN88771.1 - 3.1e-23 82.4 0.0 3.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 KZN88772.1 - 3.5e-72 243.4 0.0 4.7e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KZN88773.1 - 2.6e-19 69.7 0.1 5.4e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KZN88773.1 - 3.1e-18 66.4 0.0 7.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KZN88773.1 - 2.8e-13 49.7 0.0 1.1e-12 47.8 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KZN88773.1 - 0.0018 17.3 0.1 0.0035 16.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ABC_tran PF00005.22 KZN88774.1 - 1e-46 158.6 0.0 2e-26 92.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN88774.1 - 1.1e-32 113.5 32.2 9.5e-28 97.3 9.1 2.9 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KZN88774.1 - 6.4e-11 42.7 0.1 0.12 12.3 0.0 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KZN88774.1 - 4.3e-09 35.9 0.7 8.6e-06 25.1 0.3 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN88774.1 - 5.4e-08 33.0 0.1 0.00073 19.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KZN88774.1 - 4.1e-07 30.2 0.1 0.0015 18.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KZN88774.1 - 8.1e-07 28.3 0.1 0.031 13.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KZN88774.1 - 4e-06 26.6 0.1 0.014 15.3 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KZN88774.1 - 1.4e-05 24.5 0.3 0.11 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 KZN88774.1 - 2.5e-05 24.2 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KZN88774.1 - 2.9e-05 24.5 0.1 0.036 14.5 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KZN88774.1 - 0.00011 22.1 0.3 0.19 11.7 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KZN88774.1 - 0.00016 22.4 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KZN88774.1 - 0.0021 17.7 1.1 1.1 8.8 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KZN88774.1 - 0.0031 17.3 0.7 0.42 10.3 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 KZN88774.1 - 0.005 16.2 0.1 2.3 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KZN88774.1 - 0.0075 16.6 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN88774.1 - 0.009 16.1 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KZN88774.1 - 0.0097 15.3 2.3 4.3 6.6 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain ATP-synt_ab PF00006.20 KZN88774.1 - 0.012 15.0 0.2 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KZN88774.1 - 0.016 14.6 0.4 6.7 6.1 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KZN88774.1 - 0.019 15.2 0.0 6.9 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KZN88774.1 - 0.023 14.2 0.0 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KZN88774.1 - 0.025 14.3 0.4 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 KZN88774.1 - 0.034 13.7 0.6 4.4 6.9 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA PF00004.24 KZN88774.1 - 0.04 14.1 0.1 2.2 8.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KZN88774.1 - 0.042 13.3 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KZN88774.1 - 0.057 13.1 0.2 8.7 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Septin PF00735.13 KZN88774.1 - 0.065 12.2 0.2 4.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 KZN88774.1 - 0.093 12.4 0.4 2 8.0 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 KZN88774.1 - 0.14 11.0 0.0 13 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KZN88774.1 - 0.16 11.8 0.1 3.5 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain Endonuc_subdom PF09062.5 KZN88774.1 - 0.22 12.2 0.0 0.62 10.8 0.0 1.7 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain Rad17 PF03215.10 KZN88774.1 - 0.27 9.8 0.1 0.6 8.7 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KZN88774.1 - 0.31 10.6 0.1 17 4.9 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase Acyl_transf_1 PF00698.16 KZN88775.1 - 9.6e-57 192.7 0.0 1e-55 189.2 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 KZN88775.1 - 4.6e-30 103.1 0.1 1e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KZN88775.1 - 1.1e-27 95.8 0.0 2.4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KZN88775.1 - 4.3e-13 49.1 0.3 5.2e-12 45.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KZN88775.1 - 0.083 12.0 0.0 4.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase RTA1 PF04479.8 KZN88776.1 - 1.9e-24 86.4 5.0 2.6e-24 85.9 3.5 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 KZN88776.1 - 0.37 9.7 6.7 0.58 9.1 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3007 PF11460.3 KZN88776.1 - 3.5 7.7 5.1 4.5 7.3 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3007) UPF0542 PF15086.1 KZN88776.1 - 6.4 6.5 7.2 36 4.1 3.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Ank PF00023.25 KZN88777.1 - 1.1e-35 119.7 1.9 3.1e-08 33.0 0.3 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KZN88777.1 - 2.4e-30 104.6 0.2 8.8e-14 51.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN88777.1 - 2.3e-26 91.2 4.1 2.3e-09 37.2 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN88777.1 - 1.1e-24 83.9 0.3 0.0001 22.2 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KZN88777.1 - 1.2e-24 86.1 0.1 5.3e-13 49.0 0.1 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.16 KZN88777.1 - 0.0046 16.8 1.9 0.0077 16.1 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor Cut8_N PF14482.1 KZN88777.1 - 3.2 7.8 9.7 0.21 11.6 2.5 2.2 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Asp PF00026.18 KZN88778.1 - 1e-43 149.7 0.1 1.6e-43 149.1 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KZN88778.1 - 4.2e-07 30.3 0.7 9.2e-05 22.8 0.2 3.1 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 KZN88778.1 - 0.0018 18.1 0.2 0.082 12.8 0.0 2.7 3 0 0 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KZN88778.1 - 0.014 15.2 1.1 0.048 13.4 0.1 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease GMC_oxred_N PF00732.14 KZN88779.1 - 6.7e-64 215.8 0.0 8.1e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN88779.1 - 4.3e-35 121.1 0.0 7.4e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KZN88779.1 - 1.4e-06 28.5 0.2 0.027 14.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN88779.1 - 4.1e-06 26.8 0.3 0.0011 18.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN88779.1 - 7.6e-06 25.0 0.2 0.0067 15.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN88779.1 - 6.4e-05 22.9 0.0 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN88779.1 - 6.5e-05 22.0 1.2 0.0019 17.1 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN88779.1 - 0.00084 19.1 1.6 0.049 13.4 0.0 2.7 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KZN88779.1 - 0.0029 16.5 0.1 0.0058 15.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN88779.1 - 0.0033 15.9 0.2 0.029 12.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KZN88779.1 - 0.017 15.5 0.4 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN88779.1 - 0.024 13.7 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KZN88779.1 - 0.085 11.4 0.3 0.14 10.7 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 KZN88780.1 - 3.8e-36 124.5 31.8 3.8e-36 124.5 22.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KZN88780.1 - 0.11 12.4 4.9 1.9 8.5 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Amidohydro_1 PF01979.15 KZN88781.1 - 3e-34 119.1 0.6 3.8e-34 118.8 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KZN88781.1 - 9.8e-17 61.8 0.1 1.8e-15 57.6 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KZN88781.1 - 7.3e-11 41.7 0.0 2.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN88781.1 - 1.8e-10 40.6 2.2 9.9e-09 34.8 0.1 2.4 1 1 1 2 2 2 2 Amidohydrolase family DHO_dh PF01180.16 KZN88781.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Fungal_trans PF04082.13 KZN88782.1 - 5.1e-21 74.7 0.2 6.1e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain HET PF06985.6 KZN88785.1 - 3.6e-09 36.9 1.2 2.9e-07 30.7 0.1 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF953 PF06110.6 KZN88787.1 - 2.6e-12 46.2 0.0 2.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KZN88787.1 - 4.6e-05 22.9 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin FAD_binding_4 PF01565.18 KZN88788.1 - 2.6e-20 72.2 0.3 4.3e-20 71.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN88788.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like LRR_9 PF14580.1 KZN88791.1 - 2.9e-53 180.0 0.0 4.8e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KZN88791.1 - 1.5e-09 37.2 4.4 0.00056 19.4 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN88791.1 - 1.4e-07 31.1 5.2 0.0048 16.6 0.4 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KZN88791.1 - 0.0013 18.4 4.7 5 7.5 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KZN88791.1 - 0.021 14.9 5.7 16 6.2 0.0 4.7 4 0 0 4 4 4 0 Leucine rich repeat HTH_38 PF13936.1 KZN88791.1 - 0.06 12.9 0.4 0.16 11.5 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_6 PF13516.1 KZN88791.1 - 0.97 9.7 4.8 58 4.2 0.1 4.5 4 1 0 4 4 4 0 Leucine Rich repeat GDA1_CD39 PF01150.12 KZN88792.1 - 2.7e-103 345.8 0.0 3.6e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ammonium_transp PF00909.16 KZN88793.1 - 8.9e-112 373.4 25.9 1e-111 373.2 18.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 KZN88793.1 - 0.094 12.6 0.2 0.094 12.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1691) AAA PF00004.24 KZN88796.1 - 1.8e-48 164.0 0.0 8.9e-42 142.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KZN88796.1 - 6.8e-08 32.1 0.0 2.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KZN88796.1 - 2.5e-06 27.5 0.0 9.2e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KZN88796.1 - 6.9e-06 26.1 2.3 1.8e-05 24.8 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 KZN88796.1 - 4e-05 23.3 0.0 0.0012 18.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN88796.1 - 0.00015 21.9 0.0 0.0031 17.6 0.0 2.8 2 1 0 2 2 1 1 AAA domain Bromodomain PF00439.20 KZN88796.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Sigma54_activ_2 PF14532.1 KZN88796.1 - 0.00077 19.5 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KZN88796.1 - 0.0013 18.5 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KZN88796.1 - 0.0019 17.7 0.1 0.0098 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KZN88796.1 - 0.0021 18.2 0.0 0.0065 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KZN88796.1 - 0.003 17.2 0.2 0.048 13.4 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 KZN88796.1 - 0.0037 18.0 0.0 0.032 15.0 0.0 2.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KZN88796.1 - 0.011 14.9 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KZN88796.1 - 0.011 15.1 1.8 0.025 13.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KZN88796.1 - 0.013 15.3 0.0 0.047 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KZN88796.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 KZN88796.1 - 0.018 14.1 0.0 0.059 12.3 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KZN88796.1 - 0.032 13.7 0.0 0.98 8.8 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KZN88796.1 - 0.043 13.4 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KZN88796.1 - 0.052 12.4 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KZN88796.1 - 0.091 12.4 0.0 0.9 9.1 0.0 2.5 2 1 0 2 2 2 0 NACHT domain Zot PF05707.7 KZN88796.1 - 0.11 11.8 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PhoH PF02562.11 KZN88796.1 - 0.16 11.1 0.0 0.45 9.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KZN88796.1 - 0.21 11.4 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Sec66 PF09802.4 KZN88797.1 - 1.2e-81 272.6 0.5 1.4e-81 272.4 0.4 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Duffy_binding PF05424.6 KZN88797.1 - 0.23 11.2 8.5 0.81 9.4 5.9 1.8 1 1 0 1 1 1 0 Duffy binding domain PPR_2 PF13041.1 KZN88798.1 - 1.1e-05 25.3 0.8 3.8 7.5 0.0 5.0 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 KZN88798.1 - 1.2e-05 25.1 1.7 0.57 10.6 0.0 6.6 9 0 0 9 9 9 2 Pentatricopeptide repeat domain HTH_AsnC-type PF13404.1 KZN88798.1 - 0.023 14.2 1.4 0.12 11.9 0.4 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TPR_14 PF13428.1 KZN88798.1 - 1.8 9.4 9.0 3 8.7 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ORC3_N PF07034.6 KZN88799.1 - 5.8e-32 110.9 0.0 8.6e-31 107.1 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus P4Ha_N PF08336.6 KZN88799.1 - 0.025 14.3 0.2 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spc7_N PF15402.1 KZN88800.1 - 0.05 11.6 0.2 0.065 11.2 0.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Nop14 PF04147.7 KZN88801.1 - 2.8e-280 931.9 37.2 3.3e-280 931.7 25.8 1.0 1 0 0 1 1 1 1 Nop14-like family COesterase PF00135.23 KZN88802.1 - 3.4e-97 326.3 0.1 3.8e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN88802.1 - 3e-09 36.7 0.1 1.5e-08 34.4 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN88802.1 - 0.00031 20.0 0.1 0.00048 19.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN88802.1 - 0.0055 16.4 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4187 PF13821.1 KZN88803.1 - 3.8e-18 64.8 2.7 1e-17 63.4 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KZN88803.1 - 1.8e-07 30.7 0.0 7.6e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 G-patch domain DbpA PF03880.10 KZN88806.1 - 0.0054 16.3 0.1 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 DbpA RNA binding domain Peptidase_S49_N PF08496.5 KZN88807.1 - 0.076 12.8 7.9 0.61 9.8 3.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFS_1 PF07690.11 KZN88808.1 - 1.5e-33 116.0 15.0 1.5e-33 116.0 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88808.1 - 6.6e-11 41.4 3.1 6.6e-11 41.4 2.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.14 KZN88808.1 - 1.3e-05 23.9 10.3 0.00056 18.5 2.9 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.8 KZN88808.1 - 0.00021 19.6 0.5 0.00036 18.8 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KZN88808.1 - 0.00023 19.7 3.1 0.00023 19.7 2.1 3.0 2 1 1 3 3 3 1 MFS/sugar transport protein DUF791 PF05631.9 KZN88808.1 - 0.0049 15.6 0.0 0.0093 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KZN88808.1 - 0.18 9.8 10.3 0.056 11.5 1.9 2.6 2 1 1 3 3 3 0 Transmembrane secretion effector Kinetocho_Slk19 PF12709.2 KZN88809.1 - 4.7e-23 81.0 26.3 1.1e-22 79.9 4.8 4.2 4 1 0 4 4 4 2 Central kinetochore-associated DUF4407 PF14362.1 KZN88809.1 - 0.8 8.5 33.9 2.3 7.0 16.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 KZN88809.1 - 4.7 7.3 9.9 43 4.2 1.8 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KZN88809.1 - 8.4 6.2 15.1 0.17 11.6 2.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fungal_trans PF04082.13 KZN88810.1 - 1.2e-35 122.6 1.5 2e-35 121.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88810.1 - 0.00072 19.4 17.6 0.0014 18.4 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88811.1 - 2e-14 53.0 0.0 3.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.14 KZN88812.1 - 3.2e-26 91.6 0.1 4.8e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin PF00085.15 KZN88813.1 - 2e-63 210.5 4.9 4.5e-32 109.8 0.1 4.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KZN88813.1 - 6e-52 176.1 5.6 5.7e-39 133.8 0.4 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.12 KZN88813.1 - 2e-12 46.5 1.7 3.2e-12 45.9 0.6 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.1 KZN88813.1 - 9.5e-11 41.8 4.6 0.0018 18.4 0.8 4.2 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KZN88813.1 - 2.2e-10 40.4 0.2 0.0027 17.6 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KZN88813.1 - 2.3e-10 40.4 0.3 0.00076 19.5 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Redoxin PF08534.5 KZN88813.1 - 8.2e-10 38.3 4.8 0.0087 15.6 0.1 3.4 3 0 0 3 3 3 3 Redoxin AhpC-TSA PF00578.16 KZN88813.1 - 1.1e-09 38.0 2.8 5.8e-05 22.7 0.0 3.6 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_3 PF13192.1 KZN88813.1 - 0.053 13.3 0.7 0.29 10.9 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain Mu-like_Com PF10122.4 KZN88813.1 - 0.42 9.7 1.2 25 4.0 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Thioredoxin_4 PF13462.1 KZN88813.1 - 5.2 7.0 10.6 11 6.0 0.0 3.9 4 1 0 4 4 4 0 Thioredoxin ATG22 PF11700.3 KZN88814.1 - 5.9e-218 724.1 12.5 6.7e-218 723.9 8.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KZN88814.1 - 2.5e-08 33.0 20.1 2.5e-08 33.0 14.0 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN88814.1 - 0.0018 16.7 28.2 0.041 12.2 7.5 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Med14 PF08638.6 KZN88815.1 - 1.7e-73 246.0 0.0 2.8e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 DNA_pol_E_B PF04042.11 KZN88816.1 - 1e-48 165.4 0.0 1.3e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SHNi-TPR PF10516.4 KZN88817.1 - 4.6e-14 51.3 1.2 7.9e-14 50.6 0.1 2.0 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 KZN88817.1 - 1.2e-07 31.6 3.5 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN88817.1 - 1e-06 28.2 2.9 0.024 14.2 0.4 2.8 3 0 0 3 3 3 2 TPR repeat CCDC-167 PF15188.1 KZN88817.1 - 0.016 15.1 3.8 0.069 13.1 2.6 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TPR_9 PF13371.1 KZN88817.1 - 0.075 12.8 3.3 2.2 8.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 KZN88817.1 - 0.11 12.7 5.8 1.7 8.9 1.4 3.1 3 0 0 3 3 3 0 Snapin/Pallidin TPR_2 PF07719.12 KZN88817.1 - 0.84 9.7 5.2 27 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88817.1 - 2 9.1 10.2 1.2 9.9 1.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 KZN88818.1 - 1.2e-23 82.8 0.1 2.1e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.7 KZN88818.1 - 0.016 15.1 0.4 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) RIG-I_C-RD PF11648.3 KZN88818.1 - 0.096 12.5 0.6 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I DWNN PF08783.6 KZN88819.1 - 3.9e-32 110.0 0.1 3.9e-32 110.0 0.1 2.3 3 0 0 3 3 3 1 DWNN domain zf-CCHC_2 PF13696.1 KZN88819.1 - 1.5e-05 24.3 8.7 4e-05 23.0 6.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KZN88819.1 - 0.0083 16.0 1.2 0.019 14.8 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 KZN88819.1 - 0.17 11.4 3.0 0.4 10.2 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KZN88819.1 - 3 7.5 8.2 6.5 6.5 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KZN88819.1 - 5.3 6.9 9.6 13 5.7 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KZN88819.1 - 5.8 6.7 11.4 0.31 10.7 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.16 KZN88820.1 - 5.2e-45 153.4 0.2 1.4e-44 152.1 0.1 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KZN88820.1 - 2e-29 102.4 0.0 3.2e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KZN88820.1 - 5.8e-11 42.3 0.0 5.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KZN88820.1 - 8.4e-10 38.4 0.0 2.1e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KZN88820.1 - 0.00086 18.7 0.0 0.0024 17.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 UPF0180 PF03698.8 KZN88820.1 - 0.021 14.6 0.1 2.2 8.1 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Dus PF01207.12 KZN88820.1 - 0.11 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) dCMP_cyt_deam_1 PF00383.17 KZN88821.1 - 5.5e-27 93.3 1.0 8.7e-27 92.7 0.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 KZN88821.1 - 0.00096 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KZN88821.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KZN88821.1 - 0.036 14.8 0.1 0.061 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain PSD5 PF07637.6 KZN88821.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) ThiF PF00899.16 KZN88822.1 - 1.4e-27 96.1 0.0 2.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KZN88822.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FtsJ PF01728.14 KZN88823.1 - 1.1e-56 191.7 0.0 1.3e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KZN88823.1 - 0.00026 20.7 0.0 0.00062 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN88823.1 - 0.0047 17.4 0.0 0.013 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN88823.1 - 0.018 14.6 0.0 0.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Filament PF00038.16 KZN88824.1 - 0.014 14.8 34.3 0.17 11.3 23.7 2.7 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 KZN88824.1 - 0.72 8.9 10.7 1.9 7.5 1.8 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 KZN88824.1 - 1.5 8.4 30.4 0.88 9.2 11.0 3.1 1 1 2 3 3 3 0 Mnd1 family APG6 PF04111.7 KZN88824.1 - 3.7 6.5 33.7 4.6 6.1 13.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 OST3_OST6 PF04756.8 KZN88825.1 - 1.3e-22 80.0 2.9 2.1e-22 79.4 2.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family VIT1 PF01988.14 KZN88825.1 - 0.1 12.1 11.3 0.68 9.3 1.8 2.4 1 1 1 2 2 2 0 VIT family Thioredoxin PF00085.15 KZN88825.1 - 0.17 11.6 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin NADH-u_ox-rdase PF10785.4 KZN88825.1 - 0.94 9.7 3.3 3.3 8.0 0.0 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Rft-1 PF04506.8 KZN88826.1 - 2.8e-100 336.2 13.0 3.3e-100 336.0 9.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 KZN88826.1 - 1.2e-06 27.9 4.7 1.2e-06 27.9 3.2 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein DEAD PF00270.24 KZN88827.1 - 1.2e-46 158.3 0.0 4.6e-46 156.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN88827.1 - 1.7e-26 91.8 0.3 1.3e-25 89.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN88827.1 - 1.3e-06 28.3 0.1 3.3e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 KZN88827.1 - 0.00032 19.2 0.0 0.056 11.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 KZN88827.1 - 0.0017 17.4 1.1 0.027 13.5 0.0 2.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SRP1_TIP1 PF00660.12 KZN88827.1 - 0.035 13.9 0.2 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Seripauperin and TIP1 family Rep_fac-A_C PF08646.5 KZN88828.1 - 2.5e-53 179.6 4.5 3.8e-51 172.6 0.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KZN88828.1 - 5.9e-23 80.5 0.5 1.2e-22 79.6 0.1 1.8 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KZN88828.1 - 5.5e-14 51.7 0.0 2e-09 37.2 0.0 3.7 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain UCH PF00443.24 KZN88829.1 - 1.3e-47 162.1 0.0 1.9e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KZN88829.1 - 1.1e-22 79.8 21.1 1.2e-18 66.9 1.9 3.5 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KZN88829.1 - 1.3e-17 64.2 0.0 1e-16 61.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KZN88829.1 - 1.4e-17 62.9 0.5 1.1e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.1 KZN88829.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF1815 PF08844.5 KZN88829.1 - 0.093 12.3 0.4 1.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1815) Prim_Zn_Ribbon PF08273.7 KZN88829.1 - 0.24 11.4 0.1 0.24 11.4 0.1 5.1 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase RNA_pol_N PF01194.12 KZN88830.1 - 5.4e-30 103.2 1.7 6.4e-30 102.9 1.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 KZN88831.1 - 0.00013 21.7 16.5 0.00022 20.9 0.1 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat Kelch_2 PF07646.10 KZN88831.1 - 0.061 13.1 0.9 0.75 9.6 0.2 3.1 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 KZN88831.1 - 0.31 11.2 2.8 1.6 9.0 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Clr5 PF14420.1 KZN88832.1 - 6.3e-19 67.6 1.2 1.9e-18 66.1 0.8 1.9 1 0 0 1 1 1 1 Clr5 domain DUF2407_C PF13373.1 KZN88832.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Het-C PF07217.6 KZN88834.1 - 4.6e-270 897.0 0.0 6.7e-270 896.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zip PF02535.17 KZN88834.1 - 1.8 7.5 4.9 3.1 6.7 3.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter FAD-oxidase_C PF02913.14 KZN88835.1 - 1.2e-56 191.8 0.1 3.8e-56 190.1 0.1 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KZN88835.1 - 1.3e-36 125.1 0.0 3.3e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain ADH_N PF08240.7 KZN88836.1 - 2.7e-35 120.4 0.2 6.1e-35 119.2 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88836.1 - 2.4e-20 72.4 0.3 4.8e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KZN88836.1 - 0.00077 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KZN88836.1 - 0.0025 18.3 0.0 0.0057 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN88836.1 - 0.0043 17.9 0.1 0.0073 17.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN88836.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 KZN88836.1 - 0.082 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 KZN88836.1 - 0.092 12.3 1.4 0.16 11.4 0.7 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 KZN88836.1 - 0.13 11.3 0.3 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.17 KZN88837.1 - 8.8e-40 135.7 0.0 1.4e-39 135.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN88837.1 - 3e-13 50.3 0.0 5.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN88837.1 - 9.4e-11 41.2 0.0 1.1e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN88837.1 - 0.00034 19.8 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KZN88837.1 - 0.002 17.5 0.0 0.0055 16.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KZN88837.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KZN88837.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KZN88837.1 - 0.024 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KZN88837.1 - 0.038 13.1 0.0 0.06 12.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KZN88837.1 - 0.074 12.5 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KZN88837.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KZN88837.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN88837.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3295 PF11702.3 KZN88839.1 - 5.2 5.9 10.0 6.1 5.7 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) zf-Mss51 PF13824.1 KZN88840.1 - 8.9e-29 99.1 6.8 2e-28 98.0 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KZN88840.1 - 0.015 15.1 0.3 0.015 15.1 0.2 1.8 2 0 0 2 2 2 0 MYND finger zf-HIT PF04438.11 KZN88840.1 - 0.31 10.7 2.3 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 HIT zinc finger Oxysterol_BP PF01237.13 KZN88841.1 - 4.3e-131 436.6 0.1 1.2e-130 435.1 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.6 KZN88841.1 - 5.7e-35 119.9 0.2 1.3e-34 118.7 0.2 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_2 PF12796.2 KZN88841.1 - 7.7e-16 58.2 0.0 2.6e-10 40.4 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN88841.1 - 8.7e-16 57.5 0.6 1.2e-09 38.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KZN88841.1 - 4.7e-15 54.5 0.1 0.0013 18.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KZN88841.1 - 1.1e-12 46.8 0.0 0.0033 17.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KZN88841.1 - 1.6e-12 47.5 0.2 8.1e-07 29.3 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 KZN88841.1 - 2.7e-10 40.3 0.2 6.8e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KZN88841.1 - 1.2e-06 28.4 0.9 2.8e-06 27.2 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Exonuc_VII_S PF02609.11 KZN88841.1 - 0.041 13.6 0.1 2.1 8.2 0.0 2.8 2 0 0 2 2 2 0 Exonuclease VII small subunit Raptor_N PF14538.1 KZN88842.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.6 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain MA-Mit PF09245.5 KZN88842.1 - 0.11 11.8 0.1 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Peptidase_C14 PF00656.17 KZN88842.1 - 0.11 12.2 0.0 0.36 10.4 0.0 1.7 2 1 0 2 2 2 0 Caspase domain Glyco_tranf_2_3 PF13641.1 KZN88843.1 - 1.4e-24 87.1 0.1 2e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KZN88843.1 - 5.9e-07 28.9 0.0 0.00049 19.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KZN88843.1 - 1.5e-05 24.7 0.0 3.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 ADH_zinc_N PF00107.21 KZN88846.1 - 3.2e-30 104.3 1.5 5.8e-30 103.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN88846.1 - 2.6e-08 33.6 0.0 2.2e-07 30.6 0.0 2.5 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN88846.1 - 5e-08 33.9 0.1 1.4e-07 32.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KZN88846.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HupF_HypC PF01455.13 KZN88846.1 - 0.13 12.2 0.4 0.79 9.7 0.1 2.4 2 0 0 2 2 2 0 HupF/HypC family AlaDh_PNT_C PF01262.16 KZN88846.1 - 0.31 10.5 4.0 0.086 12.4 0.7 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Clr5 PF14420.1 KZN88847.1 - 1.5e-12 47.2 1.6 2.5e-12 46.5 1.1 1.4 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 KZN88848.1 - 2.5e-72 243.2 0.3 3.8e-72 242.6 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN88848.1 - 1.6e-14 53.5 0.0 3.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN88848.1 - 4.2e-09 36.4 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KZN88848.1 - 8.5e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 KZN88848.1 - 0.00037 20.2 6.8 0.00037 20.2 4.7 2.4 2 0 0 2 2 2 1 HSA DEAD_2 PF06733.10 KZN88848.1 - 0.0047 16.3 0.2 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 NDUF_B8 PF05821.6 KZN88849.1 - 3.8e-08 33.1 0.0 5.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 KZN88850.1 - 1.6e-30 105.6 1.9 2.7e-30 104.9 0.0 2.4 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KZN88850.1 - 3.6e-14 52.3 0.0 9.6e-14 50.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain Pribosyltran PF00156.22 KZN88852.1 - 1.2e-17 63.8 0.0 1.5e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AIG2_2 PF13772.1 KZN88853.1 - 0.0045 17.0 0.0 0.077 13.1 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family F-box-like PF12937.2 KZN88854.1 - 0.0009 18.9 1.2 0.13 11.9 0.0 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 KZN88854.1 - 0.033 13.8 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 F-box domain AP_endonuc_2 PF01261.19 KZN88855.1 - 3.8e-26 91.6 0.0 6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Rab3-GTPase_cat PF13890.1 KZN88855.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Glyco_hydro_47 PF01532.15 KZN88856.1 - 4.2e-131 437.7 0.0 5.2e-131 437.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.27 KZN88858.1 - 2.4e-57 188.8 8.0 2.9e-09 36.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KZN88858.1 - 0.00019 20.3 1.3 0.071 11.8 0.2 2.8 1 1 1 2 2 2 2 Nup133 N terminal like TRAPP PF04051.11 KZN88859.1 - 1.8e-36 124.9 0.0 2.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 KZN88859.1 - 0.091 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) LisH PF08513.6 KZN88860.1 - 1.7e-05 24.3 0.3 4.4e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 LisH RRM_1 PF00076.17 KZN88863.1 - 3.4e-46 154.7 0.0 8.1e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN88863.1 - 4.1e-28 97.1 0.0 2e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN88863.1 - 2.6e-22 78.4 0.0 2.6e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN88863.1 - 1e-05 25.3 0.0 0.0001 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KZN88863.1 - 0.00012 21.7 0.1 0.0087 15.8 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRP7 PF12923.2 KZN88865.1 - 1e-31 109.6 9.0 1e-31 109.6 6.2 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KZN88865.1 - 0.018 14.6 0.0 2.7 7.6 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.12 KZN88865.1 - 2.8 8.3 11.6 1.4 9.3 1.7 2.8 2 1 0 2 2 2 0 Ribosomal protein L14 Rad51 PF08423.6 KZN88866.1 - 1.2e-123 411.0 0.1 1.6e-123 410.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KZN88866.1 - 2.5e-10 40.0 0.0 3.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KZN88866.1 - 9.4e-10 38.0 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KZN88866.1 - 2.8e-09 37.0 1.5 5.3e-08 32.9 0.2 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain KaiC PF06745.8 KZN88866.1 - 2.5e-08 33.3 0.0 6.4e-08 31.9 0.0 1.7 2 1 0 2 2 2 1 KaiC RNA_pol_A_CTD PF03118.10 KZN88866.1 - 0.13 11.6 0.1 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.18 KZN88867.1 - 7.1e-36 120.4 39.8 7.2e-08 32.0 1.9 5.5 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.1 KZN88867.1 - 2e-07 30.6 22.4 0.036 13.7 0.1 5.1 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 KZN88867.1 - 5.1e-05 22.8 30.4 0.11 12.2 0.3 6.0 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_2 PF13696.1 KZN88867.1 - 0.0049 16.3 26.6 0.065 12.7 0.1 5.6 5 1 1 6 6 6 4 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 KZN88867.1 - 2.9 7.9 29.1 0.27 11.2 4.5 3.4 2 1 1 3 3 3 0 DnaJ central domain UDPGP PF01704.13 KZN88868.1 - 5.2e-58 196.5 0.0 7.4e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KZN88868.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Pro_isomerase PF00160.16 KZN88869.1 - 2.6e-37 128.4 0.0 3.7e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KZN88869.1 - 6e-15 54.6 0.0 1.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN88869.1 - 1.8e-11 43.8 0.0 3.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN88869.1 - 5e-09 35.8 0.0 9.9e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KZN88870.1 - 8.3e-09 35.2 6.5 1.5e-08 34.3 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.14 KZN88871.1 - 2e-35 120.4 0.0 2.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 KZN88871.1 - 0.03 13.7 0.3 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 RRXRR protein Methyltransf_16 PF10294.4 KZN88872.1 - 1.1e-16 60.8 0.0 6.2e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KZN88872.1 - 5.3e-06 26.9 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN88872.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KZN88872.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KZN88872.1 - 0.027 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KZN88872.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KZN88872.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain IncA PF04156.9 KZN88873.1 - 0.0086 15.6 40.2 0.48 9.9 10.6 3.3 1 1 2 3 3 3 3 IncA protein DivIVA PF05103.8 KZN88873.1 - 0.072 13.1 30.1 0.69 9.9 0.1 3.8 2 1 2 4 4 4 0 DivIVA protein DUF948 PF06103.6 KZN88873.1 - 0.36 10.7 10.2 3.7 7.4 0.5 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 KZN88873.1 - 2.1 7.8 25.7 0.24 10.9 1.8 3.6 3 1 1 4 4 4 0 Septum formation initiator Fib_alpha PF08702.5 KZN88873.1 - 4 7.5 20.5 1.7 8.7 3.2 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 KZN88873.1 - 5.3 7.4 26.2 1.7 9.0 3.8 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 KZN88873.1 - 9.1 4.6 20.9 4.5 5.5 12.4 1.8 1 1 1 2 2 2 0 AAA domain CLTH PF10607.4 KZN88874.1 - 7e-34 116.6 0.0 1.3e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KZN88874.1 - 2.2e-23 82.6 0.3 3.4e-23 82.0 0.2 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KZN88874.1 - 0.00083 19.0 0.3 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 KZN88875.1 - 9.4e-63 212.1 19.3 1.2e-62 211.8 13.4 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DnaJ PF00226.26 KZN88876.1 - 6.2e-17 61.1 0.2 1.1e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 KZN88877.1 - 4.7e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_polI_A34 PF08208.6 KZN88877.1 - 1.2 8.7 45.5 0.1 12.2 22.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Pyr_redox_2 PF07992.9 KZN88878.1 - 7.4e-23 81.4 0.0 1.5e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KZN88878.1 - 3.2e-15 55.4 0.0 9e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KZN88878.1 - 1.2e-13 51.2 1.1 4.8e-12 46.1 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN88878.1 - 5.7e-05 23.2 0.0 0.0016 18.5 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KZN88878.1 - 0.00098 19.3 0.0 0.004 17.4 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.1 KZN88878.1 - 0.0023 17.7 0.4 1.4 8.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.6 KZN88878.1 - 0.0088 15.2 0.1 0.03 13.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 KZN88878.1 - 0.011 15.7 0.7 1.3 9.0 0.0 3.0 2 1 1 3 3 3 0 TrkA-N domain Arrestin_N PF00339.24 KZN88880.1 - 2.8e-13 49.9 0.2 1.3e-08 34.8 0.0 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Val_tRNA-synt_C PF10458.4 KZN88883.1 - 0.1 12.7 0.4 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Aldo_ket_red PF00248.16 KZN88884.1 - 2.7e-64 216.7 0.0 3.6e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1537 PF07005.6 KZN88884.1 - 1.7e-22 80.2 0.8 3e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 FMN_dh PF01070.13 KZN88885.1 - 9.8e-111 370.0 0.0 1.2e-110 369.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KZN88885.1 - 3.4e-18 65.2 0.0 8.8e-18 63.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KZN88885.1 - 3.6e-06 26.1 0.4 1.8e-05 23.8 0.0 1.9 1 1 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 KZN88885.1 - 0.00014 20.8 0.6 0.00072 18.5 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KZN88885.1 - 0.0011 18.1 0.5 0.069 12.2 0.0 2.5 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 KZN88885.1 - 0.0019 17.4 1.4 0.0032 16.6 0.1 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KZN88885.1 - 0.022 14.0 0.0 0.13 11.4 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein Ribosomal_L23eN PF03939.8 KZN88885.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain DHO_dh PF01180.16 KZN88885.1 - 0.15 11.0 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Epimerase PF01370.16 KZN88886.1 - 8.4e-20 71.2 0.0 1.1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN88886.1 - 5e-09 35.2 0.0 7.2e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN88886.1 - 1.5e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KZN88886.1 - 6.1e-08 31.9 0.0 6.4e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KZN88886.1 - 1.9e-07 30.2 0.0 5.5e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 KZN88886.1 - 1.1e-06 28.4 0.0 2.8e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN88886.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Ldh_1_N PF00056.18 KZN88886.1 - 0.002 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 KZN88886.1 - 0.038 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KZN88886.1 - 0.055 12.3 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Zn_clus PF00172.13 KZN88887.1 - 4.3e-09 36.1 7.0 7.4e-09 35.3 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88887.1 - 0.00091 18.1 0.1 0.0017 17.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 KZN88888.1 - 8.4e-44 149.3 0.0 1.1e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family BNR_2 PF13088.1 KZN88889.1 - 8.5e-78 261.4 0.8 9.9e-78 261.1 0.5 1.0 1 0 0 1 1 1 1 BNR repeat-like domain PSII_BNR PF14870.1 KZN88889.1 - 0.0044 16.0 0.5 0.087 11.7 0.0 2.6 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 KZN88889.1 - 0.032 14.0 28.5 0.31 11.0 0.3 5.7 6 0 0 6 6 6 0 BNR/Asp-box repeat Sugar_tr PF00083.19 KZN88890.1 - 1.5e-101 340.1 13.9 1.9e-101 339.8 9.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN88890.1 - 1.5e-25 89.6 17.6 1.5e-25 89.6 12.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KZN88891.1 - 2.7e-52 177.3 0.0 3.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IDO PF01231.13 KZN88892.1 - 3e-41 141.2 0.0 4.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 KZN88893.1 - 2.5e-15 55.8 5.8 1.2e-11 44.0 1.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KZN88893.1 - 2.3e-10 39.5 6.8 0.0073 16.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88893.1 - 3.9e-09 36.9 3.4 0.00018 22.0 0.4 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88893.1 - 3.4e-08 33.4 3.9 0.017 15.6 0.0 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 KZN88893.1 - 4.6e-07 29.3 0.1 1.5e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 KZN88893.1 - 4.3e-06 26.1 7.0 0.66 9.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88893.1 - 4.4e-06 26.9 1.2 0.0063 16.8 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN88893.1 - 1.3e-05 25.0 3.5 0.017 15.0 0.3 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN88893.1 - 1.4e-05 24.5 0.1 0.012 15.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 KZN88893.1 - 0.00033 20.3 0.1 0.00074 19.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 KZN88893.1 - 0.0011 18.7 3.9 3.1 8.3 0.0 7.1 8 0 0 8 8 5 1 Leucine rich repeat TPR_17 PF13431.1 KZN88893.1 - 0.0013 18.7 0.8 0.31 11.3 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat LRR_8 PF13855.1 KZN88893.1 - 0.0026 17.4 1.1 1.3 8.8 0.0 4.8 5 1 0 5 5 5 1 Leucine rich repeat TPR_9 PF13371.1 KZN88893.1 - 0.0038 17.0 1.4 0.26 11.1 0.3 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN88893.1 - 0.0057 16.7 0.4 0.03 14.4 0.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 LRR_6 PF13516.1 KZN88893.1 - 0.028 14.4 8.3 0.9 9.7 0.0 5.8 7 0 0 7 7 4 0 Leucine Rich repeat LRR_4 PF12799.2 KZN88893.1 - 0.033 13.8 10.1 0.39 10.4 0.0 5.8 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KZN88893.1 - 0.12 12.5 4.9 17 5.9 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat TPR_6 PF13174.1 KZN88893.1 - 0.25 11.8 5.6 3.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.3 KZN88894.1 - 5.3e-42 143.2 9.0 5.3e-42 143.2 6.2 2.6 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KZN88894.1 - 0.0069 15.4 8.4 0.0069 15.4 5.8 2.4 3 0 0 3 3 3 1 Autophagy protein Apg6 Alpha-E PF04168.7 KZN88894.1 - 0.56 9.5 11.7 0.035 13.4 4.1 1.9 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. FlaC_arch PF05377.6 KZN88894.1 - 1.2 9.1 3.9 2.5 8.0 0.3 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF465 PF04325.8 KZN88894.1 - 1.8 8.3 9.5 2.9 7.6 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF465) TBPIP PF07106.8 KZN88894.1 - 2.6 7.5 19.5 0.91 9.0 6.0 3.3 4 0 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prominin PF05478.6 KZN88894.1 - 9 3.6 8.5 13 3.1 5.9 1.1 1 0 0 1 1 1 0 Prominin HlyD PF00529.15 KZN88894.1 - 9.1 5.4 18.8 0.1 11.9 6.9 2.0 2 0 0 2 2 2 0 HlyD family secretion protein ADH_N PF08240.7 KZN88895.1 - 2.3e-22 78.8 0.8 3.7e-22 78.1 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN88895.1 - 3.9e-16 58.7 0.1 6.2e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88895.1 - 7.5e-06 26.8 0.0 1.5e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN88895.1 - 0.026 13.7 1.1 0.046 12.8 0.7 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RTA1 PF04479.8 KZN88896.1 - 2.1e-49 168.0 17.2 2.1e-49 168.0 11.9 2.0 2 1 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.13 KZN88897.1 - 8.5e-08 31.9 10.9 1.4e-07 31.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN88897.1 - 2.3e-07 29.7 0.0 2.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleopor_Nup85 PF07575.8 KZN88899.1 - 6.2e-23 80.8 0.4 1.2e-12 46.8 0.0 3.5 4 0 0 4 4 4 3 Nup85 Nucleoporin DUF2890 PF11081.3 KZN88899.1 - 0.19 11.7 4.5 0.59 10.1 3.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BOF PF04076.8 KZN88900.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein PPV_E2_C PF00511.12 KZN88901.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 E2 (early) protein, C terminal Pkinase PF00069.20 KZN88902.1 - 1.9e-16 60.0 0.0 3.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88902.1 - 1.6e-15 56.8 0.0 2.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos_3 PF14582.1 KZN88902.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Fungal_trans PF04082.13 KZN88904.1 - 1.2e-11 44.0 0.0 2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88904.1 - 7e-09 35.4 7.9 1.1e-08 34.8 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN88905.1 - 9.1e-38 129.8 35.4 1.5e-32 112.7 16.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN88906.1 - 4.9e-06 25.6 0.1 8.5e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88906.1 - 1.3e-05 24.9 10.1 2.5e-05 24.0 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 KZN88907.1 - 2.7e-36 124.9 34.7 3.3e-36 124.6 24.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KZN88907.1 - 0.0013 17.6 13.0 0.0013 17.6 9.0 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF679 PF05078.7 KZN88907.1 - 0.43 10.2 6.1 0.25 10.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF679) DUF2649 PF10854.3 KZN88907.1 - 1 9.5 7.1 2 8.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) GWT1 PF06423.7 KZN88907.1 - 3 7.9 14.8 0.13 12.3 2.7 3.0 2 2 0 2 2 2 0 GWT1 CAAD PF14159.1 KZN88907.1 - 8.6 6.0 10.4 1.4 8.6 0.3 3.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Glyco_hydro_76 PF03663.9 KZN88908.1 - 2.7e-106 356.0 17.6 3.3e-106 355.7 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 KZN88910.1 - 1e-40 139.5 54.3 4.7e-40 137.3 36.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KZN88911.1 - 0.00052 19.8 8.7 0.0012 18.6 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88911.1 - 0.0007 18.5 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 KZN88912.1 - 5.6e-74 248.8 0.1 1e-73 247.9 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN88912.1 - 3.7e-65 218.9 0.6 1.4e-63 213.7 0.0 3.5 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 KZN88912.1 - 9.8e-58 195.9 0.2 2e-57 194.9 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KZN88912.1 - 1.4e-50 171.4 0.1 1.4e-49 168.2 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 KZN88912.1 - 4.2e-45 154.1 0.0 7.5e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KZN88912.1 - 4.6e-37 126.4 0.3 4.6e-37 126.4 0.2 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN88912.1 - 1.4e-18 66.6 0.0 7.7e-18 64.2 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN88912.1 - 6.1e-15 56.2 0.0 9.3e-14 52.4 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 KZN88912.1 - 8.5e-06 25.9 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN88912.1 - 8.9e-06 24.8 0.1 2.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KZN88912.1 - 0.00099 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.16 KZN88912.1 - 0.019 14.7 0.5 0.048 13.4 0.3 1.7 1 0 0 1 1 1 0 ThiF family ketoacyl-synt PF00109.21 KZN88913.1 - 3.3e-63 213.5 0.0 6.1e-63 212.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN88913.1 - 6.6e-44 150.5 0.0 9.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KZN88913.1 - 2.7e-37 127.2 0.7 9.1e-37 125.5 0.1 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KZN88913.1 - 6.4e-14 52.7 0.0 1.2e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KZN88913.1 - 4.9e-10 39.5 0.4 1.3e-09 38.1 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 KZN88913.1 - 7.9e-09 35.0 0.0 9.6e-08 31.5 0.0 2.3 1 1 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KZN88913.1 - 0.08 11.9 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain HET PF06985.6 KZN88914.1 - 1.1e-08 35.2 0.2 2.7e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RhgB_N PF09284.5 KZN88915.1 - 1.2e-79 267.2 6.2 2.1e-79 266.4 4.3 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KZN88915.1 - 5.3e-51 172.5 0.0 2.1e-50 170.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KZN88915.1 - 2.1e-12 46.9 0.4 2.5e-11 43.5 0.1 2.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CARDB PF07705.6 KZN88915.1 - 0.011 15.7 6.2 2.9 7.9 0.1 3.6 3 1 0 3 3 3 0 CARDB DUF2012 PF09430.5 KZN88915.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Toxin_37 PF11415.3 KZN88917.1 - 0.35 10.5 7.8 4.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Antifungal peptide termicin NAPRTase PF04095.11 KZN88918.1 - 4.9e-51 173.3 0.1 6.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Pkinase PF00069.20 KZN88919.1 - 4.6e-18 65.2 0.0 7.4e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN88919.1 - 2.4e-17 62.9 0.0 3.2e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN88919.1 - 0.00086 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN88919.1 - 0.0034 17.1 2.2 0.0076 16.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family GATase PF00117.23 KZN88920.1 - 0.00057 19.3 0.0 0.00068 19.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I FAD_binding_4 PF01565.18 KZN88921.1 - 2.5e-19 69.1 2.6 4e-19 68.4 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KZN88921.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 KZN88922.1 - 5.6e-13 49.1 0.1 1.1e-12 48.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN88922.1 - 3.9e-05 23.3 0.1 0.00012 21.7 0.1 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN88922.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN88922.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L12 PF00542.14 KZN88922.1 - 0.084 12.8 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Asn_synthase PF00733.16 KZN88924.1 - 2.6e-52 177.8 0.0 4e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KZN88924.1 - 4e-35 120.2 0.0 8.4e-35 119.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KZN88924.1 - 2.8e-30 104.9 0.0 6.2e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KZN88924.1 - 0.00021 20.5 0.0 0.00043 19.5 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 KZN88924.1 - 0.039 12.5 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase GATase_2 PF00310.16 KZN88924.1 - 0.071 11.8 0.1 0.92 8.1 0.0 2.4 1 1 2 3 3 3 0 Glutamine amidotransferases class-II AMP-binding PF00501.23 KZN88925.1 - 4.9e-150 499.5 0.0 2.4e-82 276.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KZN88925.1 - 3.7e-64 216.4 0.0 2e-32 112.2 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KZN88925.1 - 2.8e-20 72.3 0.1 1.3e-09 38.1 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN88925.1 - 3.8e-15 56.5 0.1 8.1e-06 26.7 0.0 3.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KZN88925.1 - 0.13 10.8 0.9 0.7 8.3 0.0 2.5 3 0 0 3 3 3 0 GH3 auxin-responsive promoter Fungal_trans PF04082.13 KZN88926.1 - 5.4e-28 97.5 1.0 5.4e-28 97.5 0.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain CTNNBL PF08216.6 KZN88928.1 - 2e-34 117.3 1.7 1.7e-33 114.3 0.3 2.8 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KZN88928.1 - 0.0059 16.3 0.1 9.7 6.1 0.0 3.8 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KZN88928.1 - 0.015 15.5 5.1 0.9 9.8 0.1 3.9 2 1 1 3 3 3 0 HEAT repeats Mo25 PF08569.6 KZN88928.1 - 0.017 14.1 0.5 0.045 12.7 0.1 1.9 1 1 0 1 1 1 0 Mo25-like RNA_pol_Rpb2_6 PF00562.23 KZN88929.1 - 3.5e-123 411.1 0.1 6.7e-123 410.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KZN88929.1 - 1.4e-61 206.9 0.0 2.3e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KZN88929.1 - 1.3e-46 158.3 0.0 2.3e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KZN88929.1 - 1.6e-30 105.1 0.0 3.6e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KZN88929.1 - 4.5e-24 84.0 1.2 1e-23 82.9 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KZN88929.1 - 4.8e-23 80.7 0.2 2.2e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KZN88929.1 - 9.3e-23 79.9 0.1 2.1e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Methyltransf_23 PF13489.1 KZN88931.1 - 7.1e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN88931.1 - 0.0092 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2931 PF11153.3 KZN88931.1 - 0.065 12.5 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) Methyltransf_18 PF12847.2 KZN88931.1 - 0.077 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S64 PF08192.6 KZN88933.1 - 2.1e-05 23.1 0.0 2.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 KZN88933.1 - 0.0047 16.9 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KZN88933.1 - 0.037 13.6 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Trypsin Neisseria_TspB PF05616.8 KZN88934.1 - 3.1 6.0 7.1 3.8 5.7 4.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ING PF12998.2 KZN88935.1 - 1.7e-24 86.1 3.5 2.6e-24 85.4 2.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KZN88935.1 - 2.9e-08 33.2 9.8 5e-08 32.5 6.8 1.4 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.8 KZN88935.1 - 0.00082 19.3 7.7 0.00082 19.3 5.3 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF4200 PF13863.1 KZN88935.1 - 0.008 16.1 0.9 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Cwf_Cwc_15 PF04889.7 KZN88935.1 - 0.011 15.4 5.4 0.023 14.3 3.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PHD_2 PF13831.1 KZN88935.1 - 0.91 8.8 5.3 1.8 7.9 3.6 1.5 1 0 0 1 1 1 0 PHD-finger ATG16 PF08614.6 KZN88935.1 - 3.8 7.2 7.8 17 5.2 0.0 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) RNA_pol_Rpc34 PF05158.7 KZN88936.1 - 4.9e-119 397.3 0.0 5.5e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 KZN88936.1 - 0.017 14.8 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 KZN88936.1 - 0.078 12.7 0.1 0.39 10.5 0.0 2.1 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family MarR PF01047.17 KZN88936.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 MarR family TPR_11 PF13414.1 KZN88937.1 - 3.4e-57 189.9 22.5 1.3e-17 63.2 0.9 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KZN88937.1 - 3.9e-45 149.6 21.6 1.5e-06 27.5 0.1 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KZN88937.1 - 6.6e-36 119.3 20.8 0.0001 21.9 0.3 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KZN88937.1 - 2.4e-24 85.4 11.2 7.9e-05 23.2 0.0 6.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KZN88937.1 - 4.4e-22 77.8 18.7 1.8e-09 37.4 0.1 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN88937.1 - 3.1e-16 58.4 12.0 0.11 13.2 0.0 9.3 4 3 6 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KZN88937.1 - 3.9e-13 49.5 13.6 0.013 15.8 0.1 7.3 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN88937.1 - 7e-13 47.3 19.5 7.2e-05 22.2 0.2 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN88937.1 - 1.7e-11 43.3 10.8 0.0035 17.4 0.1 8.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN88937.1 - 4.2e-10 39.3 8.2 0.0055 16.5 0.0 5.9 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN88937.1 - 6.1e-09 35.0 12.9 0.0029 17.2 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KZN88937.1 - 6e-06 26.0 3.2 0.12 12.2 0.0 5.4 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KZN88937.1 - 0.00028 21.1 21.6 0.25 11.9 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat RPN7 PF10602.4 KZN88937.1 - 0.00033 20.0 10.4 0.38 10.1 0.2 5.3 3 2 2 5 5 5 2 26S proteasome subunit RPN7 TPR_20 PF14561.1 KZN88937.1 - 0.00034 20.6 19.9 0.0013 18.8 0.1 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat MIT PF04212.13 KZN88937.1 - 0.012 15.5 22.4 0.083 12.7 2.6 6.1 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KZN88937.1 - 0.07 12.9 14.4 1.6 8.5 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN88937.1 - 0.072 13.0 9.7 12 5.9 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2937 PF11157.3 KZN88937.1 - 0.34 10.2 6.0 0.23 10.8 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Alkyl_sulf_dimr PF14863.1 KZN88937.1 - 0.36 11.0 9.6 2.6 8.2 0.0 4.0 3 2 1 5 5 4 0 Alkyl sulfatase dimerisation C2 PF00168.25 KZN88938.1 - 1.8e-66 220.0 1.7 2.2e-19 69.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KZN88938.1 - 0.14 12.2 0.4 0.69 10.0 0.0 2.3 3 0 0 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 KZN88938.1 - 0.2 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Fungal_trans PF04082.13 KZN88940.1 - 1.9e-12 46.6 0.0 3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88940.1 - 1.4e-06 28.0 9.7 2.7e-06 27.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88941.1 - 1e-23 83.5 3.3 1.9e-23 82.6 2.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88941.1 - 5.4e-09 35.8 10.8 1.5e-08 34.4 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.19 KZN88942.1 - 8e-24 84.1 0.1 4.8e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_I PF01487.10 KZN88942.1 - 0.14 11.7 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Type I 3-dehydroquinase MFS_1 PF07690.11 KZN88943.1 - 6.5e-35 120.4 24.6 8.7e-27 93.7 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_B_C PF00032.12 KZN88943.1 - 4.4 7.5 8.1 1.3 9.2 2.0 2.7 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD AMP-binding PF00501.23 KZN88944.1 - 5.4e-64 216.1 0.0 8.7e-64 215.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN88944.1 - 0.001 19.9 0.0 0.0027 18.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AT_hook PF02178.14 KZN88945.1 - 0.00015 21.0 32.9 0.013 15.0 2.0 4.4 4 0 0 4 4 4 3 AT hook motif HTH_32 PF13565.1 KZN88945.1 - 1.9 9.3 12.5 3.4 8.5 0.3 4.2 4 0 0 4 4 4 0 Homeodomain-like domain REC114-like PF15165.1 KZN88945.1 - 2.7 7.6 5.4 6.8 6.3 3.7 1.7 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like PAT1 PF09770.4 KZN88946.1 - 6.7 4.8 17.6 7 4.7 12.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_3 PF01494.14 KZN88948.1 - 4.1e-76 256.3 0.0 5.2e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KZN88948.1 - 8.9e-33 113.2 0.0 1.5e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_3 PF13738.1 KZN88948.1 - 4.4e-06 26.8 0.0 8.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN88948.1 - 1.3e-05 25.2 0.1 6.3e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN88948.1 - 1.6e-05 24.0 0.1 0.0018 17.2 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN88948.1 - 6.1e-05 23.3 0.0 0.0019 18.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN88948.1 - 0.00013 21.9 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN88948.1 - 0.00028 19.4 0.2 0.00055 18.5 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KZN88948.1 - 0.004 16.3 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN88948.1 - 0.0044 16.1 0.3 0.0099 14.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 KZN88948.1 - 0.006 15.7 0.0 0.47 9.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KZN88948.1 - 0.0071 15.3 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KZN88948.1 - 0.015 13.9 0.2 0.15 10.6 0.1 2.0 1 1 1 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 KZN88948.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KZN88948.1 - 0.061 12.1 0.1 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KZN88948.1 - 0.2 10.4 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KZN88949.1 - 8e-10 38.2 0.0 4.1e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KZN88949.1 - 1.3e-08 34.1 2.1 0.00014 20.8 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KZN88949.1 - 1.5e-06 27.1 1.7 0.0043 15.7 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 KZN88949.1 - 2e-05 23.2 0.2 0.00033 19.2 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN88949.1 - 0.00014 20.8 4.7 0.00014 20.8 3.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KZN88949.1 - 0.00041 20.3 2.7 0.00076 19.4 0.8 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN88949.1 - 0.00048 20.4 0.9 0.032 14.6 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KZN88949.1 - 0.0009 18.9 0.4 0.0016 18.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KZN88949.1 - 0.0013 18.6 1.2 0.0027 17.6 0.8 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KZN88949.1 - 0.0023 17.5 0.2 0.0046 16.5 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KZN88949.1 - 0.0094 15.0 0.2 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KZN88949.1 - 0.018 13.9 1.4 0.21 10.4 1.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KZN88949.1 - 0.025 13.4 3.5 0.04 12.7 2.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KZN88949.1 - 0.055 12.5 2.6 0.12 11.3 1.8 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN88949.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.22 KZN88950.1 - 6.2e-05 22.7 0.1 0.084 12.5 0.0 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN88950.1 - 0.00051 19.6 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Chlorosome_CsmC PF11098.3 KZN88951.1 - 0.02 14.5 5.8 0.026 14.2 4.0 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C Glycoprotein_B PF00606.13 KZN88951.1 - 0.14 10.1 3.2 0.16 9.9 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B MFS_1 PF07690.11 KZN88952.1 - 6.4e-24 84.3 38.1 9.4e-21 73.9 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88952.1 - 2.5e-18 65.9 20.6 3.8e-18 65.3 14.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1962 PF09227.5 KZN88953.1 - 7.3e-35 118.8 19.0 8.6e-35 118.5 13.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) MFS_1 PF07690.11 KZN88954.1 - 1.6e-43 148.7 35.6 1.6e-43 148.7 24.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88954.1 - 6.9e-08 31.4 36.1 5.1e-07 28.6 25.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KZN88954.1 - 5.6e-07 28.1 1.6 5.6e-07 28.1 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KZN88954.1 - 4.3e-05 21.8 0.9 4.3e-05 21.8 0.6 1.8 2 1 0 2 2 2 1 Transmembrane secretion effector Archaeal_AmoA PF12942.2 KZN88954.1 - 0.79 9.4 5.9 3.4 7.3 0.0 2.6 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) Zn_clus PF00172.13 KZN88955.1 - 0.0093 15.8 10.2 0.017 15.0 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L7Ae PF01248.21 KZN88956.1 - 4.3e-26 90.2 0.0 5.2e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KZN88956.1 - 0.00011 22.1 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 MFS_1 PF07690.11 KZN88957.1 - 9.1e-30 103.5 28.6 9.1e-30 103.5 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_6 PF08030.7 KZN88958.1 - 4.4e-19 68.9 0.0 8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KZN88958.1 - 4.7e-14 52.5 9.4 1.3e-13 51.1 6.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN88958.1 - 1.2e-06 28.2 0.1 5.5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.19 KZN88958.1 - 0.0091 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KZN88958.1 - 0.062 13.8 0.0 2.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PSDC PF12588.3 KZN88959.1 - 9.8e-55 184.0 0.0 1.4e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KZN88959.1 - 1.8e-35 122.0 0.0 3e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KZN88959.1 - 0.00065 19.3 0.6 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 KZN88959.1 - 0.14 11.9 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain COesterase PF00135.23 KZN88960.1 - 5.1e-97 325.8 0.0 7.2e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN88960.1 - 1.3e-09 37.9 0.1 4.5e-09 36.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN88960.1 - 9.7e-06 24.9 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.16 KZN88960.1 - 0.1 13.2 0.7 0.26 11.9 0.4 1.8 1 1 0 1 1 1 0 Lectin C-type domain DUF2177 PF09945.4 KZN88961.1 - 0.29 11.1 0.0 0.43 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) APH PF01636.18 KZN88962.1 - 1.7e-16 60.6 0.0 5.4e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN88962.1 - 1.5e-05 24.6 0.1 2.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KZN88962.1 - 0.015 14.6 0.0 0.066 12.5 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KZN88962.1 - 0.02 13.9 0.0 0.24 10.4 0.0 2.2 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN88962.1 - 0.028 13.5 0.0 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain MFS_1 PF07690.11 KZN88963.1 - 5.1e-22 78.0 22.7 5.1e-22 78.0 15.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Bystin PF05291.6 KZN88963.1 - 0.18 10.6 0.3 0.26 10.1 0.2 1.1 1 0 0 1 1 1 0 Bystin Arrestin_N PF00339.24 KZN88965.1 - 7.9e-05 22.5 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF2324 PF10086.4 KZN88966.1 - 0.019 14.1 0.1 0.024 13.8 0.1 1.1 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) Mid2 PF04478.7 KZN88966.1 - 0.026 13.9 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor UPF0233 PF06781.7 KZN88966.1 - 0.034 13.7 0.2 0.043 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Ferric_reduct PF01794.14 KZN88966.1 - 0.073 13.1 0.2 0.079 13.0 0.1 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF2077 PF09850.4 KZN88966.1 - 0.12 11.8 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Amidase PF01425.16 KZN88967.1 - 6.1e-86 288.9 0.0 8.3e-86 288.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 KZN88968.1 - 9.7e-07 27.7 0.3 5.5e-06 25.2 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KZN88969.1 - 2.4e-06 26.5 27.1 3.9e-05 22.5 18.8 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KZN88970.1 - 1.9e-07 30.0 0.6 1.9e-07 30.0 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN88970.1 - 1.7e-05 24.5 9.4 3.3e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EcKinase PF02958.15 KZN88971.1 - 1.1e-13 51.0 0.0 2e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KZN88971.1 - 4.1e-10 39.8 0.2 3.1e-09 36.9 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family FAD_binding_1 PF00667.15 KZN88972.1 - 6.5e-46 156.5 0.0 8.8e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KZN88972.1 - 1.2e-28 99.9 0.1 2.8e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KZN88972.1 - 1.8e-20 73.4 0.0 7.5e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KZN88972.1 - 0.097 12.5 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Ferric reductase NAD binding domain NAD_binding_10 PF13460.1 KZN88974.1 - 1.3e-14 54.6 0.0 2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN88974.1 - 3.4e-14 52.6 0.1 4.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KZN88974.1 - 5.9e-06 26.2 0.0 9.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KZN88974.1 - 2.2e-05 24.0 0.0 0.00019 20.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN88974.1 - 0.00066 19.3 0.1 0.0016 18.0 0.0 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KZN88974.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 KZN88974.1 - 0.0089 16.0 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KZN88974.1 - 0.036 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 KZN88974.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KZN88974.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 KZN88974.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain AlaDh_PNT_C PF01262.16 KZN88974.1 - 0.093 12.2 0.1 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KZN88974.1 - 0.12 11.4 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_3 PF00933.16 KZN88975.1 - 2.3e-87 292.7 0.0 3.6e-87 292.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN88975.1 - 1.6e-45 155.4 0.0 8.7e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN88975.1 - 1.9e-20 72.5 0.0 3.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 KZN88977.1 - 6.7e-20 70.9 0.2 1.1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FYVE PF01363.16 KZN88978.1 - 5.3e-20 71.0 15.5 1.3e-19 69.8 3.3 3.5 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KZN88978.1 - 1.3e-08 34.5 6.9 1.3e-08 34.5 4.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KZN88978.1 - 0.00035 20.6 15.6 0.00035 20.6 3.0 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN88978.1 - 0.018 14.7 6.0 0.018 14.7 4.1 3.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN88978.1 - 0.02 14.8 6.2 0.02 14.8 4.3 3.8 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN88978.1 - 2.1 8.2 11.4 0.15 11.9 1.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.11 KZN88978.1 - 8.2 6.3 11.6 0.083 12.7 0.8 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Zn_clus PF00172.13 KZN88979.1 - 1.8e-05 24.5 12.2 3.1e-05 23.8 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN88979.1 - 2.8e-05 23.1 0.0 4.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KZN88980.1 - 9.6e-57 192.5 0.0 1.4e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRP PF06011.7 KZN88981.1 - 1.1e-90 304.3 24.9 3.5e-90 302.6 17.3 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KZN88981.1 - 1.8e-15 57.2 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Cys_Met_Meta_PP PF01053.15 KZN88983.1 - 1.3e-61 208.0 0.0 2.7e-61 207.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KZN88983.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN88983.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KZN88983.1 - 0.052 12.5 0.0 15 4.4 0.0 2.9 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family ThiS PF02597.15 KZN88984.1 - 3.9e-11 43.2 0.0 4.3e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 ThiS family MARVEL PF01284.18 KZN88985.1 - 0.062 13.1 13.6 0.098 12.4 9.3 1.3 1 1 0 1 1 1 0 Membrane-associating domain QCR10 PF09796.4 KZN88985.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) FAD_binding_4 PF01565.18 KZN88986.1 - 7e-22 77.3 1.5 1.1e-21 76.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KZN88987.1 - 1.1e-38 132.9 49.6 1.1e-38 132.9 34.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN88987.1 - 1.5e-11 43.5 6.2 1.5e-11 43.5 4.3 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2987 PF11205.3 KZN88988.1 - 0.017 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) RNB PF00773.14 KZN88989.1 - 4e-52 177.5 0.0 4.1e-50 170.9 0.0 2.2 1 1 0 1 1 1 1 RNB domain MARVEL PF01284.18 KZN88990.1 - 1.3e-09 37.9 13.5 1.7e-09 37.6 9.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.4 KZN88991.1 - 1.1e-42 146.0 15.2 1.2e-42 145.8 10.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3671 PF12420.3 KZN88991.1 - 0.065 13.2 0.4 0.065 13.2 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function SPC25 PF06703.6 KZN88991.1 - 0.33 10.5 1.9 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Excalibur PF05901.6 KZN88992.1 - 0.051 13.9 7.5 43 4.5 0.0 5.3 5 0 0 5 5 5 0 Excalibur calcium-binding domain YpzI PF14140.1 KZN88992.1 - 0.71 9.4 18.7 4 6.9 0.0 5.3 5 0 0 5 5 5 0 YpzI-like protein AMP-binding PF00501.23 KZN88993.1 - 7.1e-67 225.6 0.0 9.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN88993.1 - 2.1e-11 44.6 0.1 6.3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 KZN88994.1 - 3e-28 97.5 3.0 7.1e-28 96.3 2.2 1.4 1 1 1 2 2 2 1 BolA-like protein SNARE PF05739.14 KZN88995.1 - 4.6e-10 39.0 1.8 4.6e-10 39.0 1.3 3.4 3 1 1 4 4 4 1 SNARE domain COG5 PF10392.4 KZN88995.1 - 0.012 15.5 8.8 0.021 14.7 0.5 3.0 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF2580 PF10824.3 KZN88995.1 - 0.022 15.0 4.3 0.42 10.9 0.1 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF2580) SLS PF14611.1 KZN88995.1 - 0.024 14.0 0.7 0.045 13.1 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Dispanin PF04505.7 KZN88995.1 - 0.033 13.7 0.2 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein GP41 PF00517.12 KZN88995.1 - 0.039 13.5 0.2 0.039 13.5 0.2 2.5 3 0 0 3 3 3 0 Retroviral envelope protein VitD-bind_III PF09164.5 KZN88995.1 - 0.087 12.4 0.3 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Syntaxin_2 PF14523.1 KZN88995.1 - 0.088 12.8 11.1 0.26 11.3 3.2 3.0 2 1 0 2 2 2 0 Syntaxin-like protein HisKA_3 PF07730.8 KZN88995.1 - 0.14 12.5 5.2 1.4 9.2 0.0 3.5 2 2 1 3 3 3 0 Histidine kinase CDC37_N PF03234.9 KZN88995.1 - 0.17 12.1 8.1 0.62 10.3 1.7 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Syntaxin PF00804.20 KZN88995.1 - 0.24 11.5 13.8 0.24 11.5 3.3 2.7 1 1 1 2 2 2 0 Syntaxin Osmo_CC PF08946.5 KZN88995.1 - 0.25 11.3 3.1 1 9.4 0.2 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil COG2 PF06148.6 KZN88995.1 - 0.61 9.9 5.1 5.2 6.9 0.1 2.8 3 1 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3708 PF12501.3 KZN88995.1 - 1.3 8.8 5.3 1 9.1 0.3 2.8 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter MCPsignal PF00015.16 KZN88995.1 - 2 7.9 9.5 0.88 9.0 2.7 2.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 KZN88995.1 - 2.9 8.2 5.8 1.9 8.8 0.0 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KZN88995.1 - 3.6 7.6 13.6 5 7.2 0.6 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 KZN88995.1 - 3.6 7.3 9.5 20 5.0 0.4 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2317 PF10079.4 KZN88995.1 - 5.3 5.5 12.3 0.25 9.9 2.7 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) ETRAMP PF09716.5 KZN88995.1 - 5.3 7.0 5.5 6.6 6.7 0.3 2.8 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PTR2 PF00854.16 KZN88996.1 - 8.9e-54 182.6 10.3 5.3e-52 176.8 7.2 2.3 1 1 0 1 1 1 1 POT family IF4E PF01652.13 KZN88997.1 - 3.8e-59 198.9 0.4 4.6e-59 198.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 KZN88998.1 - 9.3e-25 86.0 2.3 1.8e-24 85.1 1.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 KZN88999.1 - 2e-27 94.7 1.6 5.5e-27 93.3 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KZN88999.1 - 1.7e-21 75.3 0.1 3.4e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Glyco_hydro_31 PF01055.21 KZN89000.1 - 1.4e-164 548.1 2.9 1.7e-164 547.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN89000.1 - 8.2e-11 41.6 1.1 2.5e-10 40.0 0.7 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like HC2 PF07382.6 KZN89001.1 - 0.24 11.2 10.3 0.63 9.8 3.0 2.1 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 Bac_rhodopsin PF01036.13 KZN89002.1 - 2.4e-30 105.5 12.9 3e-30 105.1 9.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF805 PF05656.9 KZN89002.1 - 0.077 12.8 0.1 0.077 12.8 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF805) FA_desaturase PF00487.19 KZN89002.1 - 0.5 9.7 12.7 0.1 11.9 6.1 1.8 1 1 1 2 2 2 0 Fatty acid desaturase DUF485 PF04341.7 KZN89002.1 - 1.3 8.7 9.7 0.98 9.1 0.8 3.6 2 2 1 3 3 3 0 Protein of unknown function, DUF485 DUF2516 PF10724.4 KZN89002.1 - 2.5 8.1 7.9 5.5 7.0 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) tRNA-synt_1 PF00133.17 KZN89003.1 - 6.4e-161 536.3 0.0 8.3e-161 535.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KZN89003.1 - 3e-22 78.8 0.0 1.5e-12 46.8 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KZN89003.1 - 3.7e-20 72.2 0.4 6.4e-20 71.4 0.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KZN89003.1 - 4.4e-05 23.0 3.3 8.5e-05 22.0 2.3 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 KZN89003.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KZN89003.1 - 0.12 11.5 0.0 6.2 5.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KZN89003.1 - 0.21 10.3 0.0 0.88 8.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) ABC_membrane PF00664.18 KZN89004.1 - 1.3e-69 234.6 37.0 3.5e-35 121.7 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN89004.1 - 2.2e-66 222.3 0.0 3.1e-33 114.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN89004.1 - 1.9e-12 46.8 1.1 0.0017 17.6 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN89004.1 - 8.2e-12 45.6 0.0 0.12 12.3 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KZN89004.1 - 1e-08 34.5 0.6 0.00049 19.5 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KZN89004.1 - 1.8e-08 33.3 1.6 0.0027 16.3 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KZN89004.1 - 1.8e-07 30.4 0.0 0.0062 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN89004.1 - 8.7e-07 29.1 2.1 0.024 14.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN89004.1 - 3.7e-06 27.0 1.8 0.036 14.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KZN89004.1 - 9.7e-06 25.1 0.7 0.17 11.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KZN89004.1 - 1.2e-05 25.1 1.2 0.18 11.7 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KZN89004.1 - 1.2e-05 26.0 0.0 0.12 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KZN89004.1 - 1.6e-05 24.5 0.0 0.84 9.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KZN89004.1 - 0.00016 21.5 0.0 0.56 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN89004.1 - 0.0046 16.9 0.1 0.73 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KZN89004.1 - 0.0072 16.6 0.0 3.7 7.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KZN89004.1 - 0.014 15.0 0.1 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KZN89004.1 - 0.015 15.1 0.0 25 4.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA PF00004.24 KZN89004.1 - 0.017 15.3 0.5 43 4.3 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KZN89004.1 - 0.021 14.2 2.1 4.4 6.6 0.1 3.7 4 0 0 4 4 4 0 AAA-like domain AAA_5 PF07728.9 KZN89004.1 - 0.024 14.3 0.3 9.5 5.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KZN89004.1 - 0.027 14.7 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KZN89004.1 - 0.04 13.8 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 KZN89004.1 - 0.051 12.2 0.0 6.9 5.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.15 KZN89004.1 - 0.052 13.2 0.1 2.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KZN89004.1 - 0.069 12.2 0.0 8 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KZN89004.1 - 0.07 13.2 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase CENP-L PF13092.1 KZN89004.1 - 0.073 12.8 0.0 0.46 10.2 0.0 2.3 2 1 0 2 2 1 0 Kinetochore complex Sim4 subunit Fta1 Synapsin_N PF10581.4 KZN89004.1 - 0.078 12.8 0.0 7.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Synapsin N-terminal DUF87 PF01935.12 KZN89004.1 - 0.087 12.6 0.2 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 KZN89004.1 - 0.15 10.8 0.1 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KZN89004.1 - 0.82 8.6 0.0 14 4.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain UPF0183 PF03676.9 KZN89005.1 - 3.1e-38 131.4 0.0 3.3e-28 98.3 0.0 4.0 4 0 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 KZN89006.1 - 1.8e-110 368.7 0.5 1.8e-110 368.7 0.3 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KZN89006.1 - 5.3e-08 33.1 2.9 5.3e-08 33.1 2.0 4.8 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 KZN89006.1 - 0.00014 21.6 15.0 0.029 14.2 0.0 5.2 2 1 3 7 7 7 2 Baculovirus polyhedron envelope protein, PEP, C terminus TBCA PF02970.11 KZN89006.1 - 1.2 9.2 22.0 0.015 15.3 2.0 4.5 4 2 0 4 4 4 0 Tubulin binding cofactor A HrpA_pilin PF09589.5 KZN89006.1 - 7.7 6.9 11.5 0.52 10.7 0.9 3.5 1 1 2 3 3 3 0 HrpA pilus formation protein zf-Apc11 PF12861.2 KZN89008.1 - 9.3e-47 156.8 10.1 1e-46 156.6 7.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KZN89008.1 - 3.2e-32 110.4 11.0 3.6e-32 110.2 7.6 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KZN89008.1 - 9.9e-07 28.4 18.7 7.4e-06 25.7 12.7 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN89008.1 - 0.0007 19.2 13.4 0.04 13.5 9.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KZN89008.1 - 0.0058 16.5 14.6 0.099 12.6 10.1 2.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 KZN89008.1 - 0.0097 15.4 11.8 0.4 10.2 6.0 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 KZN89008.1 - 0.013 15.5 13.5 0.14 12.1 9.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN89008.1 - 0.016 14.9 14.5 0.11 12.2 10.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain Opy2 PF09463.5 KZN89008.1 - 0.051 13.6 7.6 0.19 11.8 2.7 2.3 2 1 0 2 2 2 0 Opy2 protein zf-C3HC4 PF00097.20 KZN89008.1 - 0.08 12.6 15.0 0.59 9.8 10.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KZN89008.1 - 0.52 10.0 12.9 2 8.1 9.0 2.0 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 KZN89008.1 - 1.6 8.3 5.4 2.7 7.5 3.8 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 KZN89008.1 - 2.3 8.4 10.9 8.7 6.5 7.6 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain RecR PF02132.10 KZN89008.1 - 2.5 7.6 5.8 6.9 6.1 0.3 3.0 3 0 0 3 3 3 0 RecR protein zf-HIT PF04438.11 KZN89008.1 - 2.6 7.7 8.1 0.2 11.3 0.9 2.3 3 0 0 3 3 2 0 HIT zinc finger zf-RING-like PF08746.6 KZN89008.1 - 3.4 7.7 11.3 19 5.3 7.8 2.2 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 KZN89008.1 - 4.2 7.4 10.5 1.1 9.3 4.7 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.2 KZN89008.1 - 5 7.0 10.6 1.9e+02 1.9 7.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon RINGv PF12906.2 KZN89008.1 - 5.4 7.1 12.8 12 5.9 8.1 2.2 1 1 1 2 2 2 0 RING-variant domain Rhodanese PF00581.15 KZN89009.1 - 1e-17 64.5 0.0 5e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 KZN89010.1 - 0.00013 22.1 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 PIN domain RPEL PF02755.10 KZN89011.1 - 1e-28 97.8 14.3 2.9e-10 39.1 0.9 3.6 3 0 0 3 3 3 3 RPEL repeat PPV_E1_N PF00524.13 KZN89011.1 - 0.15 12.2 4.2 0.2 11.9 2.9 1.2 1 0 0 1 1 1 0 E1 Protein, N terminal domain DUF4174 PF13778.1 KZN89011.1 - 0.16 12.1 2.6 1.7 8.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) Translin PF01997.11 KZN89012.1 - 4e-68 228.9 0.0 4.6e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Translin family Glyco_hydro_2 PF00703.16 KZN89013.1 - 1.4e-15 57.6 0.3 4.3e-15 56.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KZN89013.1 - 6.4e-12 45.3 0.2 1.9e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KZN89013.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 KZN89014.1 - 1.8e-21 76.1 0.2 3.5e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89014.1 - 2.8e-06 27.1 14.6 5.3e-06 26.2 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3712 PF12505.3 KZN89015.1 - 2.2e-24 85.8 1.3 2.7e-24 85.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Mannosyl_trans PF05007.8 KZN89017.1 - 3.6e-76 256.2 14.1 4.6e-76 255.8 9.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KZN89017.1 - 1.7e-11 43.5 3.6 1.7e-11 43.5 2.5 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KZN89017.1 - 4.4e-08 32.9 30.2 4.4e-08 32.9 20.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2029) FHA PF00498.21 KZN89018.1 - 1.3e-09 38.0 0.1 2.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain IMS PF00817.15 KZN89019.1 - 3.1e-43 147.1 0.5 7.4e-43 145.9 0.4 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KZN89019.1 - 1.3e-17 63.8 0.1 4.6e-17 62.1 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KZN89019.1 - 1.7e-06 27.7 0.0 5.5e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.9 KZN89019.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Barrier to autointegration factor DUF1875 PF08961.5 KZN89020.1 - 0.025 13.9 0.7 0.83 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) DUF2236 PF09995.4 KZN89021.1 - 4.9e-09 35.8 0.1 1.6e-08 34.1 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MARVEL PF01284.18 KZN89022.1 - 5.8e-08 32.6 22.6 9.4e-08 31.9 15.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF420 PF04238.7 KZN89022.1 - 0.29 11.0 17.2 0.026 14.4 8.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF420) TMEM52 PF14979.1 KZN89022.1 - 0.45 10.4 0.1 0.45 10.4 0.1 1.9 2 0 0 2 2 2 0 Transmembrane 52 TMEM192 PF14802.1 KZN89022.1 - 5 5.9 8.9 5.8 5.7 2.1 2.4 1 1 1 2 2 2 0 TMEM192 family DnaJ-X PF14308.1 KZN89023.1 - 1.7e-67 226.6 4.9 1.7e-67 226.6 3.4 3.0 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KZN89023.1 - 2.7e-25 87.8 1.6 4.1e-25 87.2 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain DIT1_PvcA PF05141.7 KZN89023.1 - 0.045 13.0 0.3 0.076 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Peptidase_S64 PF08192.6 KZN89023.1 - 2.6 6.2 7.4 3.4 5.8 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 SQS_PSY PF00494.14 KZN89024.1 - 5.4e-40 137.3 0.0 9.7e-40 136.5 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Synaptobrevin PF00957.16 KZN89024.1 - 0.024 14.2 0.1 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Synaptobrevin Hemerythrin PF01814.18 KZN89025.1 - 1.9e-13 50.6 3.3 2.4e-13 50.3 2.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_9 PF13371.1 KZN89025.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 KZN89026.1 - 8e-14 51.4 0.1 1.2e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN89026.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN89026.1 - 2.8e-05 24.2 0.3 4.5e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN89026.1 - 4e-05 23.2 0.0 0.00018 21.1 0.1 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.1 KZN89026.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN89026.1 - 0.0045 16.8 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KZN89026.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN89026.1 - 0.02 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 KZN89027.1 - 9.9e-14 51.1 0.0 5.1e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KZN89027.1 - 0.0048 15.8 0.0 0.0095 14.8 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KZN89027.1 - 0.045 12.6 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase TauD PF02668.11 KZN89028.1 - 5e-53 180.3 0.3 6e-53 180.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease PF00324.16 KZN89029.1 - 2.4e-108 362.5 41.7 2.9e-108 362.2 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN89029.1 - 1.7e-26 92.7 45.1 2.3e-26 92.3 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KZN89030.1 - 3.3e-143 477.5 29.8 3.8e-143 477.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89030.1 - 2.3e-21 75.9 38.1 5.6e-15 54.9 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 KZN89031.1 - 3.9e-17 62.3 0.9 5.4e-17 61.9 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KZN89031.1 - 1.1e-10 40.9 16.1 3.4e-10 39.4 11.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 KZN89031.1 - 0.0013 17.6 0.1 0.0034 16.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KZN89031.1 - 0.006 15.7 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase AA_permease_2 PF13520.1 KZN89032.1 - 6.2e-46 156.8 56.5 7.6e-46 156.4 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN89032.1 - 7.6e-26 90.4 47.8 9.9e-26 90.1 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 KZN89032.1 - 0.12 12.0 1.6 0.25 10.9 1.1 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Herpes_pp38 PF04846.8 KZN89033.1 - 0.1 11.9 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Acetyltransf_1 PF00583.19 KZN89034.1 - 3.4e-09 36.6 0.0 5.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KZN89034.1 - 0.00021 21.1 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN89034.1 - 0.00055 20.0 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN89034.1 - 0.00071 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN89034.1 - 0.004 17.0 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KZN89034.1 - 0.0043 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.11 KZN89035.1 - 1.4e-22 79.8 48.4 4e-22 78.4 33.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN89035.1 - 0.029 13.8 6.7 0.024 14.1 2.6 2.2 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 p450 PF00067.17 KZN89036.1 - 4.1e-58 197.0 0.0 5.4e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.10 KZN89036.1 - 0.04 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family His_Phos_2 PF00328.17 KZN89037.1 - 5.6e-16 58.7 0.0 7.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S8 PF00082.17 KZN89038.1 - 1.8e-44 151.9 19.0 2.8e-44 151.3 13.1 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KZN89038.1 - 7.8e-15 55.2 0.0 1.5e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2252 PF10009.4 KZN89039.1 - 9.5e-116 386.8 1.6 1.1e-115 386.6 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) APH PF01636.18 KZN89039.1 - 0.0012 18.6 1.1 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Reprolysin_5 PF13688.1 KZN89040.1 - 1.6e-29 103.2 6.3 2.6e-29 102.5 4.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KZN89040.1 - 1e-23 83.9 2.3 1.6e-23 83.3 1.6 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KZN89040.1 - 4.9e-16 59.2 2.1 8.6e-16 58.4 1.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KZN89040.1 - 6.7e-13 49.2 0.6 1.4e-12 48.1 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KZN89040.1 - 0.00075 19.1 0.4 0.0028 17.2 0.3 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease MFS_1 PF07690.11 KZN89041.1 - 8.1e-28 97.1 27.1 8.1e-28 97.1 18.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1524 PF07510.6 KZN89042.1 - 8.2e-15 54.8 0.0 1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KZN89042.1 - 0.095 12.3 0.3 0.22 11.1 0.2 1.6 1 1 0 1 1 1 0 HNH endonuclease Oxidored_FMN PF00724.15 KZN89043.1 - 1.3e-65 221.6 0.0 9.4e-65 218.8 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Amidohydro_3 PF07969.6 KZN89044.1 - 3.2e-51 174.8 1.0 3.7e-51 174.6 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN89044.1 - 8.1e-10 38.3 2.3 3e-09 36.5 0.1 2.9 4 0 0 4 4 4 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN89044.1 - 3.3e-08 33.5 0.1 0.0039 16.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KZN89044.1 - 0.00095 19.2 0.0 0.00095 19.2 0.0 2.9 4 1 0 4 4 4 1 Amidohydrolase DUF1445 PF07286.7 KZN89045.1 - 5.2e-59 197.9 0.0 6.7e-59 197.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.11 KZN89046.1 - 4.7e-41 140.6 23.5 6.2e-41 140.2 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN89047.1 - 5.8e-11 41.7 0.1 1.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89047.1 - 3e-07 30.2 12.4 5.5e-07 29.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KZN89048.1 - 8.1e-65 219.1 0.0 9.3e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.26 KZN89049.1 - 1e-09 38.2 0.0 2.1e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.12 KZN89050.1 - 9.9e-139 461.5 0.0 1.1e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KZN89050.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Thioredoxin_9 PF14595.1 KZN89050.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MORN PF02493.15 KZN89051.1 - 2.2e-14 52.2 23.8 3.2e-05 23.4 0.5 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 KZN89051.1 - 1.4e-10 40.6 11.1 2.3e-10 39.9 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KZN89051.1 - 9.9e-09 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KZN89051.1 - 1e-06 28.9 0.0 0.039 14.1 0.0 2.5 2 0 0 2 2 2 2 MATH domain zf-C3HC4_2 PF13923.1 KZN89051.1 - 0.065 13.2 13.1 0.12 12.3 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 KZN89051.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 TSKS PF15358.1 KZN89051.1 - 1 7.4 2.7 1.3 7.1 0.9 1.8 2 0 0 2 2 2 0 Testis-specific serine kinase substrate zf-RING_5 PF14634.1 KZN89051.1 - 2.7 7.7 11.7 4.8 6.9 8.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Nol1_Nop2_Fmu PF01189.12 KZN89052.1 - 8.2e-93 310.8 0.0 1.3e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 KZN89052.1 - 0.0024 17.8 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KZN89052.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Blt1 PF12754.2 KZN89053.1 - 2.8e-68 230.7 0.2 7.7e-68 229.3 0.1 1.6 1 1 0 1 1 1 1 Cell-cycle control medial ring component Striatin PF08232.7 KZN89054.1 - 1.1e-41 142.3 6.2 1.1e-41 142.3 4.3 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 KZN89054.1 - 1.8e-29 100.5 13.1 8.9e-06 25.3 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KZN89054.1 - 0.076 12.7 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A XPA_C PF05181.7 KZN89055.1 - 5.4e-29 99.5 2.3 1.3e-28 98.3 1.6 1.7 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.1 KZN89055.1 - 0.015 15.0 6.2 0.21 11.4 0.5 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2_3 PF13878.1 KZN89055.1 - 0.15 11.6 2.5 3.8 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO XPA_N PF01286.13 KZN89055.1 - 0.51 10.0 12.6 0.04 13.5 4.9 1.9 2 0 0 2 2 2 0 XPA protein N-terminal ArfGap PF01412.13 KZN89055.1 - 3.8 7.3 11.2 0.092 12.5 1.9 2.5 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf PIG-P PF08510.7 KZN89056.1 - 4.8e-44 149.0 2.8 4.9e-44 148.9 0.3 1.9 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 KZN89056.1 - 0.089 10.8 0.0 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DPM2 PF07297.7 KZN89056.1 - 2.9 8.2 9.9 5.1 7.4 6.9 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 4HBT PF03061.17 KZN89057.1 - 1.9e-12 47.0 0.6 3e-12 46.4 0.4 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KZN89057.1 - 0.025 14.5 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) adh_short_C2 PF13561.1 KZN89058.1 - 1e-10 41.7 0.0 1.3e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN89058.1 - 3.1e-06 27.1 0.0 3.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF221 PF02714.10 KZN89059.1 - 4.2e-105 351.2 21.4 4.2e-105 351.2 14.8 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KZN89059.1 - 4.8e-41 139.9 1.4 4.8e-41 139.9 1.0 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KZN89059.1 - 6.6e-28 96.4 0.5 1.3e-27 95.4 0.4 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KZN89059.1 - 1.6e-18 67.0 1.0 3.4e-18 65.9 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 KZN89059.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4164 PF13747.1 KZN89059.1 - 0.61 10.2 4.0 10 6.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cellulase PF00150.13 KZN89060.1 - 1.7e-40 138.9 1.6 4.8e-40 137.5 0.3 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KZN89060.1 - 2.2e-24 85.0 9.0 6e-22 77.2 2.1 3.8 3 1 1 4 4 4 3 Carbohydrate binding domain X2 DUF544 PF04424.8 KZN89061.1 - 5.5e-10 39.1 0.0 9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 KZN89062.1 - 8e-102 340.3 0.0 1e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Shugoshin_N PF07558.6 KZN89062.1 - 0.1 12.3 0.5 0.24 11.1 0.4 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region P21-Arc PF04062.9 KZN89063.1 - 2.1e-75 252.3 0.0 1.7e-73 246.0 0.0 2.0 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.24 KZN89064.1 - 2.4e-16 60.1 0.0 4.9e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KZN89064.1 - 1.1e-15 57.3 0.0 3.6e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KZN89064.1 - 2.8e-13 49.8 0.1 8.8e-13 48.2 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KZN89064.1 - 3.3e-10 39.2 0.0 1.6e-07 30.4 0.0 2.6 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KZN89064.1 - 1.3e-07 31.8 0.2 5e-06 26.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN89064.1 - 2e-06 27.4 0.1 6.8e-06 25.7 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KZN89064.1 - 2.6e-06 27.5 0.1 0.00046 20.2 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KZN89064.1 - 8.2e-06 25.0 0.1 4.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KZN89064.1 - 1.8e-05 24.4 0.3 0.00015 21.4 0.0 2.2 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 KZN89064.1 - 2.5e-05 24.0 0.4 0.00011 21.9 0.1 2.3 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KZN89064.1 - 2.5e-05 23.1 0.0 0.11 11.1 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus DNA_pol3_delta PF06144.8 KZN89064.1 - 2.8e-05 23.6 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 KZN89064.1 - 4e-05 23.2 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KZN89064.1 - 4.8e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KZN89064.1 - 8.2e-05 21.6 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 KZN89064.1 - 0.0002 20.9 0.1 0.0017 17.9 0.1 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KZN89064.1 - 0.00049 19.3 0.3 0.65 9.1 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KZN89064.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KZN89064.1 - 0.0026 17.2 0.0 0.14 11.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KZN89064.1 - 0.006 15.6 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KZN89064.1 - 0.0072 15.7 0.6 0.021 14.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 KZN89064.1 - 0.0099 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 KZN89064.1 - 0.01 15.7 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KZN89064.1 - 0.014 14.8 0.1 3 7.1 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KZN89064.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KZN89064.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KZN89064.1 - 0.028 15.2 0.0 0.06 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KZN89064.1 - 0.038 13.1 0.2 0.21 10.7 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KZN89064.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 KZN89064.1 - 0.044 13.1 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 KZN89064.1 - 0.055 13.2 0.0 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KZN89064.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.18 KZN89064.1 - 0.11 11.2 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 KZN89064.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family His_Phos_2 PF00328.17 KZN89065.1 - 4.9e-14 52.4 0.0 6.9e-13 48.6 0.0 2.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) GNVR PF13807.1 KZN89065.1 - 3.1 7.6 4.3 8.4 6.2 0.0 2.9 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Clr5 PF14420.1 KZN89066.1 - 1.2e-10 41.0 0.2 3.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.13 KZN89066.1 - 8.5e-05 22.5 2.3 0.0042 17.1 0.5 2.2 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 KZN89066.1 - 0.00069 20.3 1.4 0.066 14.0 0.2 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_12 PF08461.5 KZN89066.1 - 0.0011 18.6 2.2 0.24 11.1 0.1 2.4 1 1 0 2 2 2 2 Ribonuclease R winged-helix domain DUF4498 PF14926.1 KZN89066.1 - 0.021 13.9 0.1 0.037 13.1 0.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4498) Sigma54_DBD PF04552.8 KZN89066.1 - 0.025 14.0 0.3 0.089 12.3 0.2 1.8 1 1 0 1 1 1 0 Sigma-54, DNA binding domain HTH_23 PF13384.1 KZN89066.1 - 0.33 10.6 2.3 16 5.3 0.0 3.2 2 1 0 2 2 2 0 Homeodomain-like domain Pro_isomerase PF00160.16 KZN89067.1 - 2.2e-38 131.8 0.0 4.1e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.12 KZN89068.1 - 6.9e-29 100.0 0.1 1.3e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 KZN89068.1 - 0.008 15.9 1.9 0.18 11.5 0.2 2.4 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding PhaP_Bmeg PF09602.5 KZN89068.1 - 0.087 12.6 0.7 0.18 11.6 0.5 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ets PF00178.17 KZN89068.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Aldo_ket_red PF00248.16 KZN89069.1 - 2.3e-21 75.8 0.0 4.8e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Nop14 PF04147.7 KZN89070.1 - 0.018 13.0 9.4 0.02 12.8 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2796 PF10986.3 KZN89070.1 - 0.046 13.6 8.6 0.061 13.2 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SDA1 PF05285.7 KZN89070.1 - 0.086 12.1 7.8 0.094 11.9 5.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KZN89070.1 - 0.1 10.5 8.8 0.13 10.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KZN89070.1 - 0.14 10.9 24.6 0.18 10.4 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.4 KZN89070.1 - 0.2 9.8 3.6 0.24 9.6 2.5 1.0 1 0 0 1 1 1 0 Transmembrane protein FYDLN_acid PF09538.5 KZN89070.1 - 0.59 10.7 18.3 0.3 11.7 11.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 KZN89070.1 - 0.65 8.4 9.0 0.78 8.1 6.2 1.2 1 0 0 1 1 1 0 Daxx Family RXT2_N PF08595.6 KZN89070.1 - 0.77 9.5 9.7 1.2 8.8 6.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2722 PF10846.3 KZN89070.1 - 2.4 7.1 7.1 2.7 6.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BTV_NS2 PF04514.7 KZN89070.1 - 3.4 6.4 6.5 4.4 6.0 4.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YL1 PF05764.8 KZN89070.1 - 8.9 5.8 8.9 10 5.6 6.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.7 KZN89070.1 - 8.9 5.9 14.8 15 5.1 10.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3431 PF11913.3 KZN89071.1 - 7.3e-87 290.4 2.2 9.7e-87 290.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) R3H PF01424.17 KZN89072.1 - 1.8e-10 40.3 0.1 3.7e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KZN89072.1 - 1.2e-06 28.3 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN89072.1 - 7e-06 25.5 0.1 1.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN89072.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 KZN89072.1 - 0.045 13.3 6.3 0.13 11.8 2.8 3.0 2 0 0 2 2 2 0 SUZ-C motif Histone PF00125.19 KZN89073.1 - 4.4e-22 77.9 0.0 5.6e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KZN89073.1 - 5.1e-05 23.2 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.4 KZN89074.1 - 2.2e-79 265.1 0.2 2.5e-79 264.9 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) GAD-like PF08887.6 KZN89074.1 - 0.081 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain DUF2576 PF10845.3 KZN89074.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Gp_dh_C PF02800.15 KZN89075.1 - 5e-74 246.9 0.1 6.8e-74 246.5 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KZN89075.1 - 1.7e-40 138.4 0.1 6.3e-40 136.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Hist_deacetyl PF00850.14 KZN89076.1 - 9.2e-85 284.6 0.1 1.5e-84 283.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KZN89076.1 - 7.4e-46 155.8 0.4 1.3e-45 155.0 0.1 1.5 2 0 0 2 2 2 1 Arb2 domain Bys1 PF04681.7 KZN89077.1 - 2.3e-15 56.6 1.4 2.7e-15 56.4 0.9 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Peptidase_M16_C PF05193.16 KZN89078.1 - 4.8e-32 111.1 0.1 7.7e-21 74.5 0.0 4.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KZN89078.1 - 5.5e-30 104.0 9.7 1.4e-29 102.8 1.9 4.0 3 2 1 4 4 4 1 Insulinase (Peptidase family M16) Phage_int_SAM_1 PF02899.12 KZN89078.1 - 0.0012 18.9 2.8 0.13 12.4 0.2 3.7 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Bac_thur_toxin PF01338.13 KZN89078.1 - 0.033 13.4 0.1 3.6 6.7 0.0 3.0 3 0 0 3 3 3 0 Bacillus thuringiensis toxin NUDIX_2 PF13869.1 KZN89079.1 - 8e-82 273.1 0.0 9.5e-82 272.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Lipase_3 PF01764.20 KZN89080.1 - 4.4e-37 126.8 0.0 6.6e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KZN89080.1 - 4.5e-07 29.5 0.1 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.7 KZN89080.1 - 0.00012 21.6 0.1 0.0007 19.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase Thioesterase PF00975.15 KZN89080.1 - 0.00073 19.8 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KZN89080.1 - 0.003 17.4 0.1 0.0054 16.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KZN89080.1 - 0.042 13.2 0.0 0.083 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KZN89080.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 KZN89080.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3431 PF11913.3 KZN89081.1 - 5.7e-91 303.9 0.2 2.3e-90 301.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) CoaE PF01121.15 KZN89082.1 - 8.1e-42 142.6 0.0 1.2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KZN89082.1 - 0.0027 18.5 0.1 0.0045 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain 2TM PF13239.1 KZN89082.1 - 0.033 14.2 0.5 0.07 13.1 0.3 1.5 1 0 0 1 1 1 0 2TM domain AAA_18 PF13238.1 KZN89082.1 - 0.054 13.8 2.2 0.68 10.2 1.5 2.4 1 1 0 1 1 1 0 AAA domain zf-Di19 PF05605.7 KZN89084.1 - 0.0053 16.8 5.8 0.34 11.0 1.5 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF1684 PF07920.6 KZN89085.1 - 0.021 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) MPP6 PF10175.4 KZN89085.1 - 0.22 11.8 0.3 0.22 11.8 0.2 2.8 2 2 1 3 3 3 0 M-phase phosphoprotein 6 SURF1 PF02104.10 KZN89085.1 - 6.2 6.6 6.6 2.4 7.9 2.7 1.6 1 1 1 2 2 2 0 SURF1 family zf-CHCC PF10276.4 KZN89086.1 - 1.9e-17 62.7 0.5 3.4e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain Mucin PF01456.12 KZN89086.1 - 0.78 9.5 4.2 1.2 8.9 2.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein UPF0047 PF01894.12 KZN89087.1 - 7.1e-41 138.7 0.0 8e-41 138.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TRI5 PF06330.6 KZN89088.1 - 2e-28 99.1 0.9 2.8e-28 98.6 0.4 1.2 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Lactamase_B PF00753.22 KZN89089.1 - 7.9e-17 61.5 2.3 1.2e-16 60.8 1.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN89089.1 - 0.0012 18.4 1.1 0.0017 17.9 0.7 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_32N PF00251.15 KZN89090.1 - 2.1e-90 303.2 2.9 2.7e-90 302.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN89090.1 - 2e-15 56.9 0.2 4e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KZN89090.1 - 0.012 14.9 1.4 0.78 8.9 0.1 2.7 1 1 0 2 2 2 0 BNR repeat-like domain BNR PF02012.15 KZN89090.1 - 0.1 12.4 0.8 0.69 9.9 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.13 KZN89091.1 - 1.7e-07 30.4 0.2 2.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NPP1 PF05630.6 KZN89092.1 - 4.8e-05 23.1 2.5 0.00016 21.5 0.1 2.5 2 1 1 3 3 3 1 Necrosis inducing protein (NPP1) GFA PF04828.9 KZN89093.1 - 3.9e-09 36.3 2.6 7e-09 35.5 1.8 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.7 KZN89093.1 - 0.25 10.9 6.4 1.5 8.4 1.2 2.4 2 0 0 2 2 2 0 LSD1 zinc finger F-box-like PF12937.2 KZN89094.1 - 0.00015 21.3 0.1 0.00044 19.9 0.1 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KZN89094.1 - 0.0058 16.2 0.3 0.19 11.4 0.0 3.4 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) DUF3431 PF11913.3 KZN89095.1 - 1.8e-81 272.8 0.1 2.2e-81 272.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PP1 PF07430.6 KZN89095.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phloem filament protein PP1 WXG100 PF06013.7 KZN89096.1 - 2.2e-09 37.1 7.7 2.8e-09 36.8 5.3 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF2580 PF10824.3 KZN89096.1 - 2.8e-06 27.5 5.0 4.5e-06 26.9 3.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2580) RmuC PF02646.11 KZN89096.1 - 0.0055 15.5 1.0 0.14 10.9 0.1 2.0 1 1 1 2 2 2 2 RmuC family MCPsignal PF00015.16 KZN89096.1 - 0.0056 16.2 3.2 0.023 14.2 2.2 1.7 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Baculo_PEP_C PF04513.7 KZN89096.1 - 0.009 15.8 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.1 KZN89096.1 - 0.023 14.5 0.3 0.036 13.8 0.2 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF2317 PF10079.4 KZN89096.1 - 0.043 12.4 0.1 0.051 12.1 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4618 PF15397.1 KZN89096.1 - 0.046 13.0 0.1 0.081 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Apolipoprotein PF01442.13 KZN89096.1 - 0.082 12.4 0.9 0.11 12.0 0.6 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 KZN89096.1 - 0.086 13.1 1.7 0.72 10.1 1.0 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mnd1 PF03962.10 KZN89096.1 - 0.1 12.2 0.6 2.6 7.6 0.1 2.0 2 0 0 2 2 2 0 Mnd1 family Sec34 PF04136.10 KZN89096.1 - 0.11 12.1 0.4 0.14 11.8 0.3 1.1 1 0 0 1 1 1 0 Sec34-like family DUF4164 PF13747.1 KZN89096.1 - 0.13 12.3 0.6 0.22 11.6 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 KZN89096.1 - 0.15 11.7 1.8 30 4.3 0.2 2.0 1 1 0 1 1 1 0 Laminin Domain II Calpain_inhib PF00748.14 KZN89096.1 - 0.24 11.7 1.3 0.29 11.4 0.9 1.2 1 0 0 1 1 1 0 Calpain inhibitor Tape_meas_lam_C PF09718.5 KZN89096.1 - 1.2 9.1 5.3 2.2 8.2 1.4 2.5 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PE PF00934.15 KZN89096.1 - 1.4 9.0 7.2 1.9 8.6 3.5 2.1 1 1 1 2 2 2 0 PE family Melibiase PF02065.13 KZN89098.1 - 8.5e-26 90.5 1.3 1.7e-20 73.1 0.0 3.4 1 1 1 2 2 2 2 Melibiase Exo_endo_phos PF03372.18 KZN89099.1 - 3.6e-23 82.7 0.1 6.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KZN89099.1 - 0.12 12.3 3.3 0.59 10.1 0.9 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-CHY PF05495.7 KZN89100.1 - 2e-13 50.2 22.5 2.6e-13 49.8 15.6 1.1 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.7 KZN89100.1 - 0.0056 16.6 12.9 0.099 12.6 4.8 2.5 1 1 1 2 2 2 2 TFIIH C1-like domain Tmemb_55A PF09788.4 KZN89100.1 - 0.27 10.3 7.0 0.3 10.1 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn_Tnp_IS1595 PF12760.2 KZN89100.1 - 0.29 10.9 12.0 11 5.8 6.5 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Transposase_21 PF02992.9 KZN89100.1 - 2.9 6.9 6.1 4.1 6.4 4.2 1.3 1 1 0 1 1 1 0 Transposase family tnp2 zf-RING_3 PF14369.1 KZN89100.1 - 5.5 7.0 13.1 0.42 10.6 3.5 2.6 1 1 1 2 2 2 0 zinc-finger Ribosomal_L37ae PF01780.14 KZN89100.1 - 9 6.2 8.5 4.2 7.2 4.0 1.8 1 1 1 2 2 2 0 Ribosomal L37ae protein family Proteasome PF00227.21 KZN89101.1 - 6.2e-54 182.1 0.1 8.2e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KZN89101.1 - 5.3e-08 32.0 0.0 5.3e-08 32.0 0.0 2.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KZN89101.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-RanBP PF00641.13 KZN89102.1 - 1e-20 72.4 9.1 6.4e-11 41.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KZN89102.1 - 1.6e-08 34.0 0.0 5.9e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN89102.1 - 1.3e-06 28.3 0.0 8.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KZN89102.1 - 1.6e-06 28.4 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 KZN89102.1 - 0.52 10.1 8.3 0.82 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cnd3 PF12719.2 KZN89103.1 - 1.7e-94 316.1 0.4 1.8e-93 312.8 0.0 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KZN89103.1 - 3.5e-08 33.6 7.9 3e-06 27.4 0.6 4.1 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KZN89103.1 - 8.2e-07 29.3 2.0 0.00048 20.5 0.1 4.4 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 KZN89103.1 - 2.9e-06 26.8 0.8 0.077 13.1 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 KZN89103.1 - 0.078 12.8 0.5 11 5.7 0.0 3.7 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 PALP PF00291.20 KZN89104.1 - 2.9e-62 210.6 0.1 3.5e-62 210.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tim17 PF02466.14 KZN89105.1 - 6.8e-52 174.8 7.5 9.1e-52 174.4 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 KZN89105.1 - 3.6 7.7 15.2 3.2 7.9 7.1 2.7 2 1 1 3 3 3 0 Bacteriocin class II with double-glycine leader peptide DUF4048 PF13257.1 KZN89106.1 - 6.2e-96 320.9 22.7 6.2e-96 320.9 15.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) Myosin_HC-like PF07058.6 KZN89106.1 - 0.6 9.1 3.3 1.5 7.8 2.3 1.7 1 0 0 1 1 1 0 Myosin II heavy chain-like ADIP PF11559.3 KZN89106.1 - 7.4 6.4 7.1 0.32 10.8 0.7 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.20 KZN89107.1 - 4.9e-08 32.4 0.0 0.00012 21.2 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.18 KZN89108.1 - 7e-15 55.4 0.0 1.3e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN89108.1 - 5.3e-06 26.1 0.1 3.9e-05 23.3 0.0 2.3 3 0 0 3 3 3 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN89109.1 - 7.5e-71 238.3 0.0 1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89109.1 - 2.6e-47 161.0 0.0 3.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN89109.1 - 2.2e-05 23.5 0.0 0.00013 21.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FAD-oxidase_C PF02913.14 KZN89110.1 - 3.8e-57 193.4 0.0 6.3e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KZN89110.1 - 5.6e-36 123.0 0.3 1.1e-35 122.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain RmlD_sub_bind PF04321.12 KZN89111.1 - 5.5e-57 192.8 0.0 6.9e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KZN89111.1 - 1e-23 84.0 0.0 2e-23 83.0 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN89111.1 - 3.5e-14 52.3 0.1 8.9e-12 44.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KZN89111.1 - 5.8e-12 44.8 0.1 4e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KZN89111.1 - 2.8e-10 39.6 0.1 4.8e-08 32.2 0.0 2.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN89111.1 - 4.4e-05 23.5 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN89111.1 - 0.00016 21.6 0.0 0.016 15.1 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN89111.1 - 0.034 13.7 0.1 7.1 6.2 0.0 2.8 3 0 0 3 3 3 0 KR domain RA PF00788.18 KZN89112.1 - 7.4e-05 23.1 0.0 0.00036 20.9 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 KZN89112.1 - 0.0089 16.2 1.2 0.025 14.7 0.9 1.7 1 1 0 1 1 1 1 PH domain TUG-UBL1 PF11470.3 KZN89112.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG RE_TdeIII PF09520.5 KZN89113.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Glyco_hydro_16 PF00722.16 KZN89114.1 - 2.4e-07 30.2 0.0 4.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TrkH PF02386.11 KZN89115.1 - 9.7e-124 412.5 15.6 9.6e-123 409.2 6.1 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1289 PF06945.8 KZN89116.1 - 0.0057 16.0 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) ADH_N PF08240.7 KZN89117.1 - 3e-05 23.7 0.0 0.00013 21.6 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN89117.1 - 7e-05 22.3 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CN_hydrolase PF00795.17 KZN89118.1 - 3.2e-21 75.5 0.0 4.4e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Poxvirus_B22R_C PF13168.1 KZN89119.1 - 0.0014 17.9 0.0 0.4 9.9 0.0 3.0 3 0 0 3 3 3 2 Poxvirus B22R protein C-terminal Dynamin_M PF01031.15 KZN89120.1 - 1.3e-105 352.4 0.3 1.3e-105 352.4 0.2 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KZN89120.1 - 4.9e-56 189.1 0.1 1e-55 188.1 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KZN89120.1 - 4.7e-30 103.3 4.4 4.7e-30 103.3 3.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KZN89120.1 - 4.9e-05 23.2 0.3 0.00047 20.0 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN89120.1 - 0.0084 16.6 0.0 0.057 13.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein ATP-synt_ab PF00006.20 KZN89121.1 - 6.1e-115 382.1 0.0 9.3e-115 381.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KZN89121.1 - 2.9e-17 63.1 0.7 5.2e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KZN89121.1 - 1.2e-15 57.5 0.7 2.5e-15 56.4 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Imm19 PF15567.1 KZN89122.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 19 DUF2236 PF09995.4 KZN89123.1 - 4.1e-35 121.2 0.0 6.9e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HTH_8 PF02954.14 KZN89123.1 - 0.022 14.3 0.0 0.063 12.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_20 PF12840.2 KZN89123.1 - 0.062 13.1 0.1 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HpcH_HpaI PF03328.9 KZN89124.1 - 1.6e-37 128.5 0.0 1.9e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Mem_trans PF03547.13 KZN89125.1 - 1e-15 56.9 8.4 9.1e-13 47.2 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein DUF2929 PF11151.3 KZN89125.1 - 0.05 13.6 0.4 0.66 10.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF4481 PF14800.1 KZN89125.1 - 0.084 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) ketoacyl-synt PF00109.21 KZN89126.1 - 8.9e-69 231.7 0.3 1.5e-68 231.0 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN89126.1 - 7.9e-64 215.9 0.0 1.2e-63 215.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KZN89126.1 - 1.2e-57 194.4 0.0 3.3e-57 193.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KZN89126.1 - 3e-55 187.4 0.0 4.6e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KZN89126.1 - 9.6e-48 162.2 0.9 2.2e-44 151.3 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN89126.1 - 4.5e-32 110.3 0.1 1e-31 109.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KZN89126.1 - 7.5e-21 74.0 0.1 3.5e-20 71.8 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KZN89126.1 - 3.1e-20 72.4 0.0 1.1e-19 70.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN89126.1 - 5.5e-14 52.2 0.0 1.7e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89126.1 - 1.9e-11 43.7 0.0 3.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89126.1 - 6.8e-11 42.7 0.0 2.6e-10 40.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN89126.1 - 1.5e-09 38.2 0.0 3.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KZN89126.1 - 7.5e-08 33.3 0.0 1e-06 29.6 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN89126.1 - 3.5e-07 29.9 0.0 9.3e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KZN89126.1 - 1e-06 28.8 0.0 3.4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN89126.1 - 0.00021 20.3 3.4 0.00021 20.3 0.3 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KZN89126.1 - 0.00032 20.7 0.0 0.00098 19.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN89126.1 - 0.0023 17.1 0.0 0.0078 15.3 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KZN89126.1 - 0.0067 15.1 0.0 0.013 14.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KZN89126.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 KZN89126.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.5 KZN89126.1 - 0.046 13.3 1.5 0.12 12.0 1.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.27 KZN89127.1 - 2.6e-29 99.9 13.7 2.6e-07 30.2 0.3 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat CLTH PF10607.4 KZN89127.1 - 1.2e-05 25.0 0.5 2.1e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain IKI3 PF04762.7 KZN89127.1 - 0.022 12.5 0.1 0.16 9.7 0.0 2.3 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.7 KZN89127.1 - 0.084 12.5 0.1 52 3.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DEAD PF00270.24 KZN89128.1 - 1e-39 135.7 0.3 2.6e-39 134.4 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN89128.1 - 1.6e-29 101.5 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KZN89128.1 - 0.0047 16.6 0.2 0.012 15.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KZN89128.1 - 0.012 15.4 0.2 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KZN89128.1 - 0.037 13.6 0.6 0.086 12.4 0.4 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KZN89128.1 - 0.046 13.4 0.5 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KZN89128.1 - 0.12 12.4 0.6 0.54 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 KZN89129.1 - 3.6e-69 232.2 0.2 3.6e-69 232.2 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KZN89129.1 - 1.6e-16 59.4 0.8 3.8e-16 58.3 0.5 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KZN89129.1 - 4.7e-08 32.9 1.7 1.8e-06 27.9 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN89129.1 - 1.5e-07 31.3 3.0 2.8e-06 27.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KZN89129.1 - 0.00097 19.2 0.3 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DNA_ligase_A_M PF01068.16 KZN89130.1 - 1.5e-21 76.7 0.0 6e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KZN89130.1 - 2.6e-10 40.3 0.0 4.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus APC8 PF04049.8 KZN89131.1 - 1.3e-53 180.5 0.1 4.3e-53 178.8 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KZN89131.1 - 2.9e-22 77.2 7.2 0.00035 20.0 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN89131.1 - 2e-21 75.3 10.5 5.9e-07 29.0 0.0 6.6 4 2 3 7 7 7 4 TPR repeat TPR_8 PF13181.1 KZN89131.1 - 1.7e-18 64.9 6.8 0.00076 19.0 0.0 8.0 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89131.1 - 1.7e-18 64.9 18.5 0.068 13.1 2.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89131.1 - 5.2e-17 62.0 15.3 6.5e-05 23.4 0.4 7.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN89131.1 - 8.4e-15 53.9 15.3 0.0076 16.8 0.0 9.0 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KZN89131.1 - 1.1e-10 41.1 10.4 6.1e-05 22.7 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN89131.1 - 4.1e-10 39.0 4.9 0.28 11.4 0.0 7.2 7 1 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN89131.1 - 5.5e-10 39.2 10.0 0.25 11.5 0.0 6.0 7 0 0 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KZN89131.1 - 6.5e-10 38.8 25.4 0.032 14.1 0.1 7.4 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KZN89131.1 - 9.9e-10 38.6 14.3 0.045 14.1 0.1 7.9 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN89131.1 - 4.9e-09 35.3 5.4 1.1 9.2 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KZN89131.1 - 4.4e-05 23.6 23.7 0.73 10.4 0.2 9.5 10 1 0 10 10 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 KZN89131.1 - 0.0033 16.5 13.0 0.0039 16.2 3.7 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 KZN89131.1 - 0.0097 14.7 0.1 5.7 5.6 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 KZN89131.1 - 0.024 14.8 0.0 2.6 8.5 0.0 3.4 3 0 0 3 3 2 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 KZN89131.1 - 0.23 11.4 18.6 17 5.4 0.0 6.9 7 1 1 8 8 7 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 KZN89132.1 - 2.1e-73 246.4 0.0 2.4e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase GatB_Yqey PF02637.13 KZN89132.1 - 0.086 12.5 1.7 0.24 11.1 1.2 1.8 1 0 0 1 1 1 0 GatB domain PHO4 PF01384.15 KZN89133.1 - 1.4e-107 359.1 11.5 1.7e-107 358.8 8.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 KZN89133.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 2.1 3 0 0 3 3 3 1 Glycophorin A Tim17 PF02466.14 KZN89133.1 - 0.079 13.0 0.3 0.079 13.0 0.2 4.0 5 1 0 5 5 5 0 Tim17/Tim22/Tim23/Pmp24 family HTH_IclR PF09339.5 KZN89133.1 - 0.081 12.5 0.1 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain ParA PF10609.4 KZN89134.1 - 8.3e-34 115.3 0.0 1.5e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KZN89134.1 - 2.7e-13 49.7 0.0 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KZN89134.1 - 5.7e-07 28.8 0.0 5.2e-06 25.7 0.0 2.0 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KZN89134.1 - 4.6e-05 23.4 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KZN89134.1 - 0.00015 20.9 1.4 0.00025 20.2 1.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 KZN89134.1 - 0.00027 20.4 0.2 0.00057 19.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KZN89134.1 - 0.0011 18.4 1.0 0.0044 16.3 0.4 2.2 1 1 1 2 2 2 1 YhjQ protein ArgK PF03308.11 KZN89134.1 - 0.0034 16.2 0.5 0.0048 15.7 0.4 1.2 1 0 0 1 1 1 1 ArgK protein AAA_26 PF13500.1 KZN89134.1 - 0.0038 16.8 0.5 0.5 9.9 0.4 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KZN89134.1 - 0.068 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase UIM PF02809.15 KZN89134.1 - 0.16 11.5 0.3 0.16 11.5 0.2 2.2 2 0 0 2 2 1 0 Ubiquitin interaction motif DUF258 PF03193.11 KZN89134.1 - 0.69 9.0 2.9 0.54 9.4 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SEP PF08059.8 KZN89135.1 - 3.9e-28 97.5 0.1 6.7e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KZN89135.1 - 1.4e-13 50.6 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KZN89135.1 - 4.5e-12 45.3 3.1 7.2e-12 44.6 2.1 1.3 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 KZN89135.1 - 0.031 14.1 0.1 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Asp_protease_2 PF13650.1 KZN89137.1 - 0.13 12.7 0.1 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Fungal_trans PF04082.13 KZN89138.1 - 1.2e-13 50.5 0.4 2.1e-13 49.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89138.1 - 3.4e-06 26.8 12.0 6e-06 26.0 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2730 PF10805.3 KZN89138.1 - 0.052 13.2 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4066 PF13278.1 KZN89139.1 - 7.8e-22 77.3 0.0 1.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KZN89139.1 - 1.4e-05 24.5 0.0 3.9e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DIT1_PvcA PF05141.7 KZN89140.1 - 4.7e-88 295.1 0.0 6.7e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 KZN89140.1 - 1.9e-27 96.5 0.0 3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family bZIP_1 PF00170.16 KZN89141.1 - 0.0014 18.5 8.3 0.0021 18.0 5.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF4149 PF13664.1 KZN89142.1 - 1.7e-19 69.7 0.8 1.7e-19 69.7 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) p450 PF00067.17 KZN89143.1 - 2.5e-47 161.4 0.0 3.2e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF572 PF04502.8 KZN89144.1 - 1.2e-62 211.9 20.5 1.4e-62 211.8 14.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zinc_ribbon_2 PF13240.1 KZN89144.1 - 0.044 13.2 0.6 0.11 12.0 0.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KZN89144.1 - 0.069 12.7 0.1 16 5.2 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Benyvirus_14KDa PF07255.6 KZN89144.1 - 0.16 11.8 0.6 0.85 9.4 0.4 2.0 1 1 1 2 2 2 0 Benyvirus 14KDa protein zf-FCS PF06467.9 KZN89144.1 - 0.19 11.3 2.9 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 KZN89144.1 - 0.25 10.6 1.1 0.43 9.8 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain ATPase-cat_bd PF12156.3 KZN89144.1 - 4.2 7.9 7.7 3.5 8.2 0.0 3.1 3 0 0 3 3 3 0 Putative metal-binding domain of cation transport ATPase TPR_11 PF13414.1 KZN89145.1 - 8.1e-30 102.2 12.4 6.3e-09 35.3 0.0 8.2 6 2 1 7 7 7 7 TPR repeat TPR_1 PF00515.23 KZN89145.1 - 6.5e-29 98.3 0.5 0.00038 19.9 0.2 10.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89145.1 - 2.1e-28 95.9 11.2 0.0035 17.1 0.2 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 KZN89145.1 - 1.8e-25 88.8 10.6 8.5e-20 70.6 0.4 5.6 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KZN89145.1 - 9.2e-19 67.5 5.9 1.8e-05 24.9 0.1 8.0 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 KZN89145.1 - 5.9e-18 64.5 21.1 6.5e-08 32.3 0.1 9.2 10 1 0 10 10 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN89145.1 - 1.8e-16 59.1 15.7 0.24 12.1 0.2 10.7 8 3 3 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89145.1 - 1e-14 54.7 21.3 2.8e-05 24.6 0.4 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN89145.1 - 1.6e-12 46.2 0.1 0.25 11.1 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN89145.1 - 1.6e-10 39.9 14.3 0.19 11.5 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN89145.1 - 9.1e-09 34.8 0.4 0.29 11.4 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KZN89145.1 - 2.1e-08 34.0 8.0 1.9 9.1 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KZN89145.1 - 4.6e-06 26.3 18.4 0.054 13.4 0.1 8.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_4 PF07721.9 KZN89145.1 - 0.016 15.5 17.3 22 5.8 0.1 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KZN89145.1 - 0.026 14.3 13.6 16 5.4 0.0 6.5 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 KZN89145.1 - 0.65 9.9 5.7 37 4.2 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 KZN89145.1 - 2.4 8.0 6.9 2.6 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.7 KZN89146.1 - 1.9e-29 102.5 0.2 2.5e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 FAT PF02259.18 KZN89147.1 - 7.2e-74 248.8 8.3 1.7e-73 247.6 5.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KZN89147.1 - 3.8e-30 105.0 0.5 2e-29 102.7 0.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KZN89147.1 - 4e-08 32.5 0.1 1.1e-07 31.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain Toxin_22 PF08092.6 KZN89149.1 - 0.17 11.7 3.0 0.28 11.0 2.1 1.4 1 0 0 1 1 1 0 Magi peptide toxin family MFS_1 PF07690.11 KZN89150.1 - 4.3e-43 147.3 44.0 4.3e-43 147.3 30.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN89150.1 - 4e-11 41.8 21.6 5.7e-11 41.3 15.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN89150.1 - 5.5e-11 41.7 23.2 1e-07 30.9 6.1 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter Trp_DMAT PF11991.3 KZN89151.1 - 1.5e-106 356.6 0.0 1.7e-106 356.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Methyltransf_11 PF08241.7 KZN89152.1 - 1.2e-12 48.1 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89152.1 - 2.5e-10 40.1 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN89152.1 - 3.9e-09 35.9 0.0 1.2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KZN89152.1 - 2.9e-08 34.0 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN89152.1 - 8.6e-08 32.4 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN89152.1 - 9.6e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN89152.1 - 6e-07 29.4 0.0 9.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89152.1 - 0.00039 20.9 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN89152.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KZN89152.1 - 0.057 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KZN89153.1 - 1.8e-39 135.5 0.3 2.4e-39 135.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF3_N PF09440.5 KZN89153.1 - 0.16 12.1 1.2 0.78 9.9 0.1 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain FAD_binding_3 PF01494.14 KZN89154.1 - 5.9e-15 55.1 9.1 5e-14 52.1 0.8 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN89154.1 - 4.2e-09 35.7 6.3 3.3e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN89154.1 - 4.9e-05 22.3 5.0 0.00074 18.4 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KZN89154.1 - 0.00099 19.0 1.3 0.0023 17.8 0.6 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN89154.1 - 0.0043 15.5 2.2 0.11 10.9 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 KZN89154.1 - 0.016 14.1 0.6 1.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KZN89154.1 - 0.037 13.6 0.2 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 KZN89154.1 - 0.065 13.2 0.4 0.23 11.4 0.3 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 KZN89155.1 - 3.8e-42 144.3 0.0 5.1e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KZN89156.1 - 7.7e-162 538.4 0.0 1.4e-80 270.7 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KZN89156.1 - 5.6e-67 225.7 0.1 4.3e-35 121.0 0.0 3.2 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KZN89156.1 - 9.4e-21 73.8 0.0 8.7e-10 38.7 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN89156.1 - 2.3e-14 54.1 0.0 6.9e-06 26.9 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain B56 PF01603.15 KZN89157.1 - 9e-173 574.5 5.8 1.1e-172 574.2 4.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Macoilin PF09726.4 KZN89157.1 - 6.4 4.9 7.5 0.43 8.8 1.9 1.4 2 0 0 2 2 2 0 Transmembrane protein DUF3016 PF11454.3 KZN89158.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Tau95 PF09734.4 KZN89160.1 - 6.6e-72 242.4 0.0 7.9e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit PfkB PF00294.19 KZN89162.1 - 2.3e-32 112.3 0.0 3.8e-32 111.6 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RNase_H PF00075.19 KZN89163.1 - 1.9e-06 28.2 0.0 0.00038 20.8 0.0 2.1 2 0 0 2 2 2 2 RNase H RNase_H PF00075.19 KZN89165.1 - 2.1e-06 28.0 0.0 0.003 17.8 0.0 2.2 2 0 0 2 2 2 2 RNase H CVNH PF08881.5 KZN89167.1 - 1.2e-30 105.7 0.6 1.4e-30 105.5 0.4 1.0 1 0 0 1 1 1 1 CVNH domain MCM PF00493.18 KZN89169.1 - 4.3e-142 472.7 0.1 5.6e-142 472.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KZN89169.1 - 1.1e-18 67.8 0.5 3.7e-18 66.1 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN89169.1 - 3.7e-06 26.2 0.0 0.0009 18.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN89169.1 - 4.2e-05 23.2 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KZN89169.1 - 0.00043 19.8 0.1 0.0015 18.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KZN89169.1 - 0.0068 16.7 0.4 0.021 15.1 0.3 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KZN89169.1 - 0.052 13.0 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.7 KZN89170.1 - 1.4e-48 164.4 0.5 1.2e-47 161.4 0.1 2.4 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KZN89170.1 - 1.6e-06 27.2 0.4 4.2e-06 25.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 KZN89170.1 - 0.0065 16.0 1.0 0.023 14.2 0.7 1.9 1 0 0 1 1 1 1 LUC7 N_terminus DUF2451 PF10474.4 KZN89170.1 - 0.048 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Glycogen_syn PF05693.8 KZN89173.1 - 0 1124.5 0.0 0 1124.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 KZN89173.1 - 5.1e-06 26.7 0.1 1.1e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KZN89173.1 - 1.5e-05 24.5 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KZN89173.1 - 6.2e-05 22.6 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain NMT1 PF09084.6 KZN89174.1 - 7.5e-76 254.4 0.0 9.9e-76 254.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KZN89174.1 - 8.8e-07 28.5 2.8 0.087 12.1 0.0 3.2 2 1 1 3 3 3 3 NMT1-like family THRAP3_BCLAF1 PF15440.1 KZN89175.1 - 6 5.3 8.7 8.4 4.9 6.0 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family COG2 PF06148.6 KZN89176.1 - 1.1e-35 122.4 1.7 1.8e-35 121.7 1.2 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KZN89176.1 - 1.4e-05 24.8 2.0 2.3e-05 24.1 0.1 2.3 2 1 1 3 3 3 1 Vps51/Vps67 COG5 PF10392.4 KZN89176.1 - 8.2e-05 22.5 0.5 0.00064 19.6 0.1 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4335 PF14233.1 KZN89176.1 - 0.0032 16.9 0.4 0.0084 15.5 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4335) DUF2450 PF10475.4 KZN89176.1 - 0.019 13.8 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Bul1_C PF04426.7 KZN89176.1 - 0.041 13.0 0.1 0.13 11.4 0.0 1.7 1 1 1 2 2 2 0 Bul1 C terminus Sec34 PF04136.10 KZN89176.1 - 0.17 11.6 1.0 0.83 9.3 0.1 2.0 1 1 1 2 2 2 0 Sec34-like family Spc7 PF08317.6 KZN89176.1 - 0.17 10.4 2.6 0.34 9.5 1.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Gasdermin PF04598.7 KZN89176.1 - 0.29 9.8 4.6 0.28 9.8 1.0 2.0 2 0 0 2 2 2 0 Gasdermin family IncA PF04156.9 KZN89176.1 - 0.64 9.5 7.1 1.8 8.1 4.9 1.7 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 KZN89176.1 - 0.83 9.5 5.4 13 5.8 0.0 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) BBP1_C PF15272.1 KZN89176.1 - 1.5 8.3 7.6 5.6 6.4 5.3 1.9 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TBPIP PF07106.8 KZN89176.1 - 2.1 7.8 7.5 1.6 8.2 1.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L1 PF00687.16 KZN89177.1 - 3.1e-30 105.1 0.0 3.4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 KZN89178.1 - 4e-99 331.2 0.0 5.7e-99 330.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KZN89178.1 - 1.9e-37 128.5 0.2 3.4e-37 127.7 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KZN89178.1 - 8.5e-08 32.5 0.1 3.3e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN89178.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KZN89178.1 - 0.031 13.4 0.3 0.072 12.1 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain E1-E2_ATPase PF00122.15 KZN89179.1 - 6.1e-75 251.1 2.9 1.3e-74 250.1 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KZN89179.1 - 1.4e-25 91.0 0.1 2.7e-25 90.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN89179.1 - 7.8e-14 52.2 0.0 1.5e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN89179.1 - 1.1e-08 34.4 0.0 2.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN89179.1 - 0.0023 17.5 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN89179.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Glyco_hydro_18 PF00704.23 KZN89180.1 - 2.8e-18 66.5 2.6 6.1e-18 65.3 1.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF605 PF04652.11 KZN89180.1 - 0.05 13.0 17.9 0.07 12.5 12.4 1.2 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KZN89180.1 - 0.06 11.6 11.5 0.08 11.2 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 KZN89180.1 - 0.18 11.2 16.7 0.36 10.2 11.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med3 PF11593.3 KZN89180.1 - 0.2 10.8 17.8 0.25 10.5 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mitofilin PF09731.4 KZN89180.1 - 0.3 9.6 7.7 0.39 9.3 5.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4551 PF15087.1 KZN89180.1 - 0.49 8.6 13.5 0.71 8.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sec3_C PF09763.4 KZN89180.1 - 0.77 7.8 2.4 1 7.4 1.7 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 TFIIA PF03153.8 KZN89180.1 - 2.3 8.0 11.9 3.2 7.5 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 KZN89180.1 - 4.1 6.7 18.1 6.6 6.0 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Herpes_BLLF1 PF05109.8 KZN89180.1 - 7.9 4.3 30.0 10 3.9 20.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Strep_67kDa_ant PF06100.6 KZN89181.1 - 6.7e-103 344.6 0.0 7.7e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family DAO PF01266.19 KZN89181.1 - 0.00095 18.1 0.0 0.38 9.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN89181.1 - 0.0012 18.7 0.1 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN89181.1 - 0.0039 16.0 0.3 0.046 12.5 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NMT1 PF09084.6 KZN89182.1 - 0.00028 20.5 0.0 0.0011 18.6 0.0 1.9 1 1 1 2 2 2 1 NMT1/THI5 like Gag_p6 PF08705.6 KZN89182.1 - 0.36 10.8 3.2 0.69 9.9 2.2 1.5 1 0 0 1 1 1 0 Gag protein p6 PQ-loop PF04193.9 KZN89183.1 - 1.9e-21 75.3 3.8 1.2e-13 50.3 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.11 KZN89185.1 - 8.6e-39 133.2 32.5 8.6e-39 133.2 22.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.1 KZN89185.1 - 0.0031 17.4 1.6 0.0031 17.4 1.1 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AB Glyco_hydro_31 PF01055.21 KZN89186.1 - 1.5e-145 485.3 7.8 2.2e-145 484.8 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN89186.1 - 2.3e-23 81.8 0.1 2e-22 78.8 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 KZN89187.1 - 3.3e-55 185.5 0.0 3.8e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 KZN89188.1 - 4.5e-27 93.9 0.0 7e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KZN89188.1 - 0.0011 19.1 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.12 KZN89189.1 - 5.1e-96 321.1 0.0 7e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TGT PF01702.13 KZN89190.1 - 2.4e-41 141.6 0.0 2.9e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 KZN89191.1 - 8.4e-49 165.4 0.0 9.6e-49 165.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 KZN89191.1 - 0.00046 19.4 0.1 0.0019 17.4 0.0 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 KZN89191.1 - 0.062 13.6 0.0 1.1 9.5 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KZN89191.1 - 0.12 12.3 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain GIY-YIG PF01541.19 KZN89192.1 - 4.5e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 KZN89192.1 - 4.8e-05 23.2 3.1 7.8e-05 22.5 2.1 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 KZN89192.1 - 0.0023 17.6 3.9 0.0051 16.4 2.7 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KZN89192.1 - 0.0056 16.3 4.0 0.018 14.7 0.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 KZN89192.1 - 0.03 14.4 0.9 0.064 13.4 0.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain FYDLN_acid PF09538.5 KZN89192.1 - 0.088 13.3 2.2 0.12 12.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.1 KZN89192.1 - 0.12 12.1 6.2 0.24 11.2 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain HypA PF01155.14 KZN89192.1 - 0.23 11.1 2.2 1.3 8.7 1.5 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 KZN89192.1 - 0.41 10.4 2.8 0.43 10.3 0.6 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PLU-1 PF08429.6 KZN89193.1 - 3.9e-102 341.5 15.7 5.6e-99 331.2 10.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KZN89193.1 - 1.3e-42 144.5 0.1 3.9e-42 143.1 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KZN89193.1 - 6e-26 90.1 0.0 1.8e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KZN89193.1 - 4.7e-18 64.4 1.5 1.1e-17 63.1 1.0 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KZN89193.1 - 8.3e-18 64.2 9.4 2e-17 62.9 6.5 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 KZN89193.1 - 2e-17 62.5 31.2 2.6e-09 36.6 5.7 3.5 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.1 KZN89193.1 - 0.00076 18.7 2.7 0.00076 18.7 1.9 3.0 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 KZN89193.1 - 0.0013 18.0 9.5 0.012 14.8 1.1 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_3 PF07649.7 KZN89193.1 - 0.26 11.3 9.3 0.087 12.8 2.3 2.9 2 0 0 2 2 2 0 C1-like domain PALP PF00291.20 KZN89194.1 - 2.9e-25 89.1 0.0 3.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DHHA2 PF02833.9 KZN89195.1 - 9e-14 51.7 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KZN89195.1 - 5.4e-06 26.1 0.0 7.3e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.14 KZN89196.1 - 1.8e-08 34.5 0.0 3.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KZN89196.1 - 3.2e-08 32.9 0.1 8.3e-08 31.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN89196.1 - 2.7e-06 26.6 0.4 6.6e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KZN89196.1 - 1.5e-05 24.4 0.2 5.5e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain ketoacyl-synt PF00109.21 KZN89197.1 - 1.3e-76 257.4 0.0 2.5e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN89197.1 - 7.3e-49 166.8 0.1 2.3e-48 165.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KZN89197.1 - 5.2e-32 110.1 0.1 1.2e-31 109.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KZN89197.1 - 1.8e-25 90.4 0.0 6.1e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KZN89197.1 - 5.6e-22 77.7 5.6 5.6e-11 42.5 0.8 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KZN89197.1 - 4.6e-12 45.7 0.0 7.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KZN89197.1 - 9.3e-05 21.5 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 KZN89197.1 - 0.0011 18.9 0.1 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family HDA2-3 PF11496.3 KZN89198.1 - 2.2e-51 174.4 0.0 6.8e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KZN89198.1 - 0.01 15.4 1.2 0.026 14.1 0.8 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TMEM192 PF14802.1 KZN89198.1 - 0.16 10.7 2.2 0.35 9.6 1.5 1.5 1 0 0 1 1 1 0 TMEM192 family DUF1202 PF06717.6 KZN89198.1 - 1.1 8.4 4.9 2.2 7.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) GAS PF13851.1 KZN89198.1 - 3.4 6.8 29.8 15 4.6 6.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 KZN89198.1 - 7.8 6.3 43.9 4.1 7.2 2.5 3.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FMO-like PF00743.14 KZN89199.1 - 1.6e-43 148.6 0.0 1.1e-25 89.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN89199.1 - 2.7e-20 73.3 0.0 1.1e-19 71.3 0.0 2.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN89199.1 - 1.4e-13 50.4 0.1 2.6e-10 39.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN89199.1 - 1.5e-12 47.8 0.0 5.5e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89199.1 - 1.7e-12 47.3 0.1 1.6e-11 44.2 0.0 2.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN89199.1 - 3.3e-07 30.2 0.0 2.5e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN89199.1 - 5.9e-06 25.5 0.2 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KZN89199.1 - 0.0001 21.3 0.0 1.2 8.0 0.0 3.3 1 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN89199.1 - 0.003 16.0 0.3 0.28 9.6 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 KZN89199.1 - 0.023 15.0 0.3 9.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase POT1 PF02765.12 KZN89200.1 - 2.6e-12 46.8 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF3367 PF11847.3 KZN89200.1 - 1.8 6.4 3.7 3.4 5.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) NUDIX-like PF09296.6 KZN89201.1 - 1.5e-22 79.7 0.0 3.5e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 KZN89201.1 - 2.5e-16 59.5 0.1 4.7e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 KZN89201.1 - 2.1e-05 23.9 1.8 4.2e-05 22.9 1.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain CN_hydrolase PF00795.17 KZN89202.1 - 3.9e-30 104.6 0.0 6.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KZN89202.1 - 9.6e-18 63.9 0.0 1.9e-07 30.2 0.0 3.1 2 2 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 KZN89202.1 - 0.033 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase DUF4243 PF14027.1 KZN89204.1 - 1.9e-108 362.8 0.1 2.5e-108 362.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Helicase_C_3 PF13625.1 KZN89205.1 - 2.5e-28 98.3 0.0 9.9e-28 96.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN89205.1 - 5.3e-15 55.7 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KZN89205.1 - 2.2e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KZN89205.1 - 3.7e-12 45.6 0.2 6.8e-12 44.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 KZN89205.1 - 3e-06 26.8 0.1 6.9e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 KZN89205.1 - 0.0032 16.2 0.1 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Selenoprotein_S PF06936.6 KZN89206.1 - 0.24 10.9 2.3 0.31 10.5 1.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) APC_CDC26 PF10471.4 KZN89206.1 - 0.55 11.0 6.4 1.4 9.7 4.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 CTD_bind PF04818.8 KZN89208.1 - 0.0052 16.9 0.0 0.029 14.5 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. PAT1 PF09770.4 KZN89208.1 - 0.042 12.1 11.9 0.056 11.6 8.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF515 PF04415.7 KZN89208.1 - 3.7 5.6 6.9 5.9 5.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hydrophobin PF01185.13 KZN89209.1 - 0.011 16.1 3.2 0.019 15.4 2.2 1.4 1 0 0 1 1 1 0 Fungal hydrophobin EMP24_GP25L PF01105.19 KZN89211.1 - 6e-47 159.7 3.9 6.8e-47 159.5 2.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 KZN89211.1 - 0.029 14.2 0.2 0.081 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) USP7_ICP0_bdg PF12436.3 KZN89212.1 - 1.6e-88 296.1 0.8 7.7e-88 293.9 0.3 2.3 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KZN89212.1 - 2.6e-71 239.4 3.6 2.2e-69 233.1 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KZN89212.1 - 7.4e-56 189.2 0.9 7.4e-56 189.2 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN89212.1 - 1.4e-34 119.9 0.0 4.1e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KZN89212.1 - 3e-08 33.9 0.0 1.4e-07 31.7 0.0 2.2 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.3 KZN89212.1 - 0.00038 20.0 2.3 1.3 8.7 0.1 5.0 4 1 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.4 KZN89213.1 - 3.2e-44 150.3 0.1 9.7e-44 148.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KZN89213.1 - 4.8e-11 42.3 0.0 1.8e-09 37.3 0.0 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KZN89213.1 - 0.0089 15.8 0.0 0.7 9.6 0.0 2.4 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KZN89213.1 - 0.0094 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pmp3 PF01679.12 KZN89214.1 - 1.6e-22 78.9 9.0 2.1e-22 78.5 6.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3165 PF11364.3 KZN89214.1 - 0.045 13.8 0.8 0.068 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) NapE PF06796.6 KZN89214.1 - 2.7 7.3 4.5 3.5 6.9 3.1 1.2 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE SPC22 PF04573.7 KZN89215.1 - 1.3e-35 122.2 0.0 6.4e-25 87.3 0.0 2.2 2 0 0 2 2 2 2 Signal peptidase subunit AIG2 PF06094.7 KZN89216.1 - 7.8e-16 58.4 0.0 1.1e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Peptidase_C48 PF02902.14 KZN89217.1 - 7.7e-33 113.9 0.0 6.4e-32 110.9 0.0 2.4 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 KZN89218.1 - 1.4e-52 177.5 0.0 2e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 KZN89219.1 - 3.4e-68 229.6 0.0 5.1e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89219.1 - 7.4e-35 120.2 0.0 1.4e-34 119.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN89219.1 - 0.0012 17.8 0.0 0.0026 16.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KZN89219.1 - 0.032 13.2 0.1 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_11 PF14598.1 KZN89219.1 - 0.089 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain GTP_cyclohydroI PF01227.17 KZN89221.1 - 9.2e-73 243.3 0.4 1.2e-72 242.9 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KZN89221.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein WD40 PF00400.27 KZN89222.1 - 2.9e-42 141.0 9.6 8.3e-10 38.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KZN89222.1 - 6.8e-30 102.7 0.6 1.5e-29 101.7 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 KZN89222.1 - 0.00044 18.5 0.3 0.79 7.7 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 XRN_N PF03159.13 KZN89223.1 - 1.1e-102 342.4 0.0 2.1e-102 341.5 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus p450 PF00067.17 KZN89224.1 - 1.6e-30 106.0 0.3 4.3e-30 104.6 0.2 1.6 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KZN89225.1 - 2.4e-54 179.3 23.2 1.3e-12 47.1 0.2 12.4 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 KZN89225.1 - 3e-29 101.1 0.0 5e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KZN89225.1 - 1.1e-07 31.7 3.4 0.012 15.3 0.0 6.6 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KZN89225.1 - 1.9e-06 26.3 6.9 0.63 8.1 0.0 5.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KZN89225.1 - 0.0028 16.7 0.5 2.9 6.9 0.0 3.4 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 KZN89225.1 - 0.012 14.3 0.0 1.8 7.2 0.0 3.1 3 1 1 4 4 4 0 Coatomer WD associated region DUF1513 PF07433.6 KZN89225.1 - 0.026 13.4 0.3 2.6 6.8 0.0 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1513) PQQ_3 PF13570.1 KZN89225.1 - 0.68 10.2 7.9 2.2 8.6 0.1 5.2 6 0 0 6 6 6 0 PQQ-like domain Septin PF00735.13 KZN89226.1 - 6.2e-112 373.2 0.6 6.2e-112 373.2 0.4 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KZN89226.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN89226.1 - 5.7e-06 25.8 0.2 0.00011 21.6 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KZN89226.1 - 9.2e-05 21.6 0.0 0.00022 20.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN89226.1 - 0.0021 18.1 0.1 0.0091 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KZN89226.1 - 0.021 15.3 0.7 0.049 14.1 0.1 2.2 2 1 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KZN89226.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KZN89226.1 - 0.086 12.2 0.9 0.25 10.7 0.3 2.0 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 KZN89226.1 - 0.1 12.1 1.1 8.4 5.8 0.1 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KZN89226.1 - 0.11 12.7 0.1 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 KZN89226.1 - 0.22 11.3 6.0 0.99 9.1 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Myc-LZ PF02344.10 KZN89226.1 - 0.48 10.0 5.1 0.86 9.2 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain Ribosomal_L6e PF01159.14 KZN89226.1 - 1.8 8.8 5.5 6.9 6.9 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_23 PF13476.1 KZN89226.1 - 9.9 6.4 16.9 2.9e+02 1.6 11.7 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 KZN89227.1 - 1.5e-30 103.9 15.8 8.9e-08 31.7 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KZN89227.1 - 0.0069 16.1 0.2 0.035 13.8 0.0 2.2 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.5 KZN89227.1 - 0.0085 14.3 0.0 0.011 13.9 0.0 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein BBS2_Mid PF14783.1 KZN89227.1 - 0.056 13.2 0.0 1.1 9.0 0.0 2.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 KZN89227.1 - 0.065 12.7 0.2 0.77 9.4 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat FLgD_tudor PF13861.1 KZN89227.1 - 0.33 10.9 4.1 25 4.9 0.1 3.6 3 1 1 4 4 4 0 FlgD Tudor-like domain WI12 PF07107.6 KZN89227.1 - 0.97 9.3 4.6 0.53 10.2 0.1 2.4 2 1 0 2 2 2 0 Wound-induced protein WI12 GPS PF01825.16 KZN89227.1 - 2.7 8.1 5.6 0.62 10.2 0.4 2.4 2 1 0 2 2 2 0 Latrophilin/CL-1-like GPS domain ACT_7 PF13840.1 KZN89228.1 - 1.1e-24 85.6 0.1 2e-16 59.2 0.0 3.5 3 0 0 3 3 3 3 ACT domain Cu-oxidase_3 PF07732.10 KZN89229.1 - 3.4e-40 136.4 10.2 8.3e-40 135.1 0.3 3.4 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN89229.1 - 1.6e-37 128.0 5.2 1.6e-37 128.0 3.6 4.2 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 KZN89229.1 - 1.2e-35 122.7 1.3 2.7e-34 118.3 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Nop14 PF04147.7 KZN89230.1 - 0.18 9.6 4.6 0.19 9.6 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cecropin PF00272.14 KZN89230.1 - 0.2 11.2 0.2 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 Cecropin family TRP PF06011.7 KZN89232.1 - 6.2e-18 64.5 23.6 8e-17 60.9 16.4 2.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Scytalone_dh PF02982.9 KZN89233.1 - 1.4e-77 258.7 3.1 1.7e-77 258.4 2.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KZN89233.1 - 3e-07 30.3 1.8 3.9e-07 30.0 1.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 KZN89234.1 - 9.3e-36 123.2 1.9 1.2e-35 122.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89234.1 - 8e-31 107.6 0.0 1e-30 107.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89234.1 - 6e-19 68.3 1.2 8.6e-19 67.8 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89234.1 - 0.00021 20.8 0.2 0.00026 20.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KZN89234.1 - 0.0028 16.7 0.1 0.11 11.6 0.1 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KZN89234.1 - 0.11 12.4 1.6 0.25 11.3 1.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF1100 PF06500.6 KZN89235.1 - 1.9e-10 39.8 0.0 2.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 KZN89235.1 - 5.1e-10 39.6 0.4 2e-09 37.7 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89235.1 - 6.4e-10 38.9 0.0 1.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KZN89235.1 - 4.2e-06 26.3 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KZN89235.1 - 7.5e-05 22.0 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KZN89235.1 - 0.0008 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 KZN89235.1 - 0.03 13.7 0.0 0.2 11.0 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KZN89235.1 - 0.13 11.8 0.1 53 3.2 0.0 3.5 2 2 2 4 4 4 0 alpha/beta hydrolase fold SKIP_SNW PF02731.10 KZN89236.1 - 1.3e-67 226.1 3.7 1.3e-67 226.1 2.6 2.5 2 0 0 2 2 2 1 SKIP/SNW domain DUF3984 PF13136.1 KZN89236.1 - 2.3 7.3 24.1 7.9 5.6 16.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3395 PF11875.3 KZN89237.1 - 1.7e-45 154.3 0.0 2.8e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KZN89237.1 - 5.1e-17 61.3 0.2 1.2e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain NAAA-beta PF15508.1 KZN89238.1 - 4.2e-23 81.5 0.0 1.3e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fungal_trans PF04082.13 KZN89239.1 - 6.6e-16 57.9 1.9 1.3e-15 57.0 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89239.1 - 1.6e-05 24.6 9.8 2.9e-05 23.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L4 PF00573.17 KZN89240.1 - 2e-42 144.7 0.4 2.9e-42 144.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KZN89240.1 - 9.4e-30 102.3 0.6 9.4e-30 102.3 0.4 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Diphtheria_T PF02764.9 KZN89240.1 - 0.043 13.5 0.1 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Glyco_hydro_61 PF03443.9 KZN89241.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4625 PF15418.1 KZN89241.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF605 PF04652.11 KZN89241.1 - 5.7 6.2 8.9 7 5.9 6.1 1.2 1 0 0 1 1 1 0 Vta1 like UPF0029 PF01205.14 KZN89242.1 - 3.5e-31 107.1 0.0 5.4e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KZN89242.1 - 1.2e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF2340 PF10209.4 KZN89243.1 - 0.087 12.9 0.0 0.098 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) LCCL PF03815.14 KZN89244.1 - 4.1e-23 81.1 0.1 6.3e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Fungal_trans PF04082.13 KZN89245.1 - 1.8e-08 33.5 0.9 6.8e-08 31.6 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89245.1 - 7.9e-05 22.4 4.4 0.00014 21.7 3.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind_2 PF13725.1 KZN89245.1 - 0.1 12.7 0.1 1.5 8.9 0.1 2.4 1 1 0 1 1 1 0 Possible tRNA binding domain DUF2360 PF10152.4 KZN89245.1 - 0.39 10.9 3.2 0.31 11.3 0.5 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Asparaginase PF00710.15 KZN89246.1 - 6.9e-105 350.3 0.0 8.9e-105 350.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KZN89246.1 - 3.8e-12 46.3 0.1 8.4e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89246.1 - 2.5e-09 36.4 0.8 3.7e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KZN89246.1 - 1.1e-07 31.8 0.0 5.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN89246.1 - 1.2e-07 32.0 0.2 2.5e-05 24.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN89246.1 - 8.5e-05 22.4 0.6 0.017 15.3 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat MTTB PF06253.6 KZN89246.1 - 0.039 11.6 0.3 0.06 11.0 0.2 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.8 KZN89247.1 - 1.7e-65 220.5 0.0 2e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN89247.1 - 0.00097 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAP PF00956.13 KZN89248.1 - 1.7e-46 158.3 1.9 2.7e-46 157.6 1.3 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Bd3614_N PF14442.1 KZN89248.1 - 0.29 11.1 9.8 0.53 10.2 3.0 2.4 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Syntaxin-6_N PF09177.6 KZN89249.1 - 1.1e-23 83.4 0.8 6.9e-23 80.8 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KZN89249.1 - 9.8e-14 50.7 3.4 9.8e-14 50.7 2.4 3.1 3 0 0 3 3 3 1 SNARE domain TBPIP PF07106.8 KZN89249.1 - 0.052 13.0 2.7 0.082 12.4 0.2 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 KZN89249.1 - 0.12 12.2 1.5 3.2 7.5 0.5 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 KZN89249.1 - 0.29 10.8 2.6 0.88 9.3 0.2 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4047 PF13256.1 KZN89249.1 - 0.58 10.1 2.4 0.52 10.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) NPV_P10 PF05531.7 KZN89249.1 - 1 9.6 7.7 15 5.8 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KZN89249.1 - 1.4 9.3 5.1 1.8 8.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Adaptin_binding PF10199.4 KZN89249.1 - 1.5 9.0 7.4 2.6 8.3 5.2 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF4164 PF13747.1 KZN89249.1 - 5.8 7.1 8.7 13 5.9 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Pkinase PF00069.20 KZN89250.1 - 6.8e-62 208.9 0.0 1.2e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89250.1 - 7.8e-39 133.2 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN89250.1 - 3.4e-07 29.5 0.0 8.2e-07 28.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN89250.1 - 0.00068 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN89250.1 - 0.044 13.5 0.4 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 KZN89251.1 - 3.7e-14 53.0 0.0 9.3e-13 48.4 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN89251.1 - 0.02 13.5 0.0 0.63 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KZN89251.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Methyltransf_32 PF13679.1 KZN89252.1 - 7.1e-21 74.3 2.6 4.2e-20 71.8 1.8 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89252.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89252.1 - 0.093 13.3 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cupin_2 PF07883.6 KZN89254.1 - 6.2e-08 32.0 0.2 0.00059 19.2 0.0 2.5 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 KZN89254.1 - 2.9e-06 26.7 0.0 4.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KZN89254.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KZN89254.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.5 1 1 0 1 1 1 0 Cupin Abhydrolase_2 PF02230.11 KZN89258.1 - 2.5e-14 53.2 0.0 3.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KZN89258.1 - 2.8e-10 40.4 1.2 2e-07 31.1 0.3 2.4 1 1 2 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89258.1 - 1.3e-06 28.2 0.1 1.9e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.3 KZN89259.1 - 8.8e-40 134.5 11.0 1e-39 134.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SPX PF03105.14 KZN89260.1 - 2.8e-69 233.9 0.2 4.1e-69 233.4 0.1 1.3 1 0 0 1 1 1 1 SPX domain EXS PF03124.9 KZN89260.1 - 2e-09 36.9 0.6 3.3e-09 36.2 0.4 1.3 1 0 0 1 1 1 1 EXS family SEA PF01390.15 KZN89260.1 - 0.063 12.9 0.2 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 SEA domain CagE_TrbE_VirB PF03135.9 KZN89260.1 - 0.19 11.4 1.5 0.48 10.1 1.1 1.6 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Aa_trans PF01490.13 KZN89261.1 - 1.9e-39 135.3 39.4 2.3e-39 135.0 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 KZN89261.1 - 1.7e-05 23.6 20.2 1.7e-05 23.6 14.0 2.2 1 1 0 1 1 1 1 Spore germination protein Bax1-I PF01027.15 KZN89262.1 - 6.6e-48 163.0 30.1 7.7e-48 162.8 20.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 KZN89262.1 - 0.075 12.4 0.2 0.24 10.8 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL Aa_trans PF01490.13 KZN89263.1 - 3.1e-91 305.8 13.9 4.5e-91 305.3 9.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KZN89263.1 - 7.8e-06 24.9 15.4 7.8e-06 24.9 10.7 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family adh_short PF00106.20 KZN89264.1 - 1.3e-15 57.7 0.1 1.4e-14 54.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89264.1 - 6.5e-08 32.6 0.0 1.9e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89264.1 - 1.7e-06 27.8 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 KR domain DNA_ligase_A_C PF04679.10 KZN89264.1 - 0.087 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region DUF1479 PF07350.7 KZN89265.1 - 8.1e-166 551.6 0.0 9.4e-166 551.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF1620 PF07774.8 KZN89267.1 - 1.2e-75 253.5 0.0 2.2e-75 252.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KZN89267.1 - 4.4e-24 85.2 18.7 3.3e-21 75.8 3.4 3.2 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 KZN89267.1 - 1.2e-07 30.9 0.8 0.42 10.2 0.0 5.3 5 0 0 5 5 5 2 PQQ enzyme repeat Hira PF07569.6 KZN89267.1 - 0.1 11.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.1 KZN89267.1 - 0.49 10.7 0.0 0.49 10.7 0.0 5.1 6 0 0 6 6 6 0 PQQ-like domain FA_hydroxylase PF04116.8 KZN89268.1 - 3.7e-13 49.8 13.2 3.7e-13 49.8 9.1 2.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CRAL_TRIO PF00650.15 KZN89269.1 - 1.5e-24 86.2 0.0 2e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN89269.1 - 1.7e-10 40.8 0.5 4.3e-10 39.5 0.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.12 KZN89270.1 - 2.2e-73 243.3 0.0 1.2e-23 83.3 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KZN89270.1 - 3.1e-22 78.6 0.0 1.7e-21 76.2 0.0 2.3 3 0 0 3 3 3 1 Tudor domain SMN PF06003.7 KZN89270.1 - 0.0002 20.5 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 KZN89271.1 - 5.8e-43 146.4 3.9 7.8e-43 146.0 2.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 KZN89272.1 - 7.3e-91 304.2 0.2 9e-91 303.9 0.2 1.0 1 0 0 1 1 1 1 Transaldolase Beach PF02138.13 KZN89273.1 - 1.3e-107 359.2 0.0 2.5e-107 358.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 KZN89273.1 - 3.1e-13 49.4 0.1 6.7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KZN89273.1 - 9.8e-10 37.9 1.8 5.5e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KZN89273.1 - 3.4e-09 37.1 0.0 9.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF3937 PF13073.1 KZN89273.1 - 0.27 11.1 0.0 0.83 9.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) Peptidase_S8 PF00082.17 KZN89274.1 - 8.6e-57 192.4 11.8 1.4e-56 191.7 8.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KZN89274.1 - 9.4e-21 74.1 0.1 1.9e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cu-oxidase PF00394.17 KZN89275.1 - 2.7e-30 105.3 0.0 8.3e-30 103.7 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN89275.1 - 6.6e-29 100.0 0.2 1.5e-27 95.6 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN89275.1 - 7.3e-22 77.3 10.6 7e-20 70.9 3.1 3.6 2 2 0 2 2 2 2 Multicopper oxidase UQ_con PF00179.21 KZN89276.1 - 4.9e-39 132.9 0.0 6.2e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN89276.1 - 0.0022 17.7 0.1 0.0091 15.7 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KZN89276.1 - 0.1 12.4 0.5 0.16 11.9 0.3 1.5 1 1 0 1 1 1 0 RWD domain Dicistro_VP4 PF11492.3 KZN89277.1 - 0.28 11.2 1.5 0.38 10.7 0.3 1.7 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 AAA_16 PF13191.1 KZN89280.1 - 3.4e-10 40.2 0.1 1.7e-08 34.6 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain TPR_12 PF13424.1 KZN89280.1 - 2.4e-08 33.8 9.7 0.014 15.3 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat NACHT PF05729.7 KZN89280.1 - 8e-06 25.6 1.5 6.8e-05 22.5 0.0 3.4 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KZN89280.1 - 0.00011 22.3 1.3 0.00084 19.4 0.0 3.3 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.1 KZN89280.1 - 0.004 17.0 0.3 0.13 12.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_19 PF13245.1 KZN89280.1 - 0.037 13.7 0.0 0.15 11.8 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain TPR_16 PF13432.1 KZN89280.1 - 0.15 12.7 0.5 13 6.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 KZN89282.1 - 5.8e-55 185.3 0.1 1e-31 110.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN89282.1 - 4.7e-43 147.5 28.1 3e-26 92.4 1.4 4.2 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 KZN89282.1 - 1.6e-10 41.4 0.2 0.0042 17.0 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KZN89282.1 - 1.3e-07 32.1 0.9 7.5e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KZN89282.1 - 1.5e-07 30.9 5.5 0.01 15.1 0.2 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KZN89282.1 - 4.5e-06 26.2 0.1 0.1 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KZN89282.1 - 4.9e-05 23.2 1.5 0.038 13.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 KZN89282.1 - 6.7e-05 22.1 0.4 0.084 12.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN89282.1 - 7.7e-05 22.8 1.3 1.8 8.6 0.1 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KZN89282.1 - 0.0001 22.2 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KZN89282.1 - 0.00016 22.4 0.1 1.1 10.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN89282.1 - 0.00019 20.8 2.4 0.37 10.3 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KZN89282.1 - 0.00019 20.4 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 KZN89282.1 - 0.0003 21.2 0.1 0.89 10.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 KZN89282.1 - 0.00032 20.2 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 KZN89282.1 - 0.00038 20.5 2.0 0.78 9.6 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KZN89282.1 - 0.00068 18.7 2.5 0.2 10.7 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KZN89282.1 - 0.0017 17.8 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KZN89282.1 - 0.0027 18.0 0.2 2.2 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KZN89282.1 - 0.0063 16.2 0.5 0.6 9.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KZN89282.1 - 0.016 14.6 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KZN89282.1 - 0.034 14.3 0.7 3 8.0 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN89282.1 - 0.036 13.9 0.2 2.4 8.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KZN89282.1 - 0.086 11.4 1.9 4.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 KZN89282.1 - 0.12 12.2 2.8 2.3 7.9 0.0 2.8 3 0 0 3 3 2 0 Dynamin family NACHT PF05729.7 KZN89282.1 - 0.12 12.0 2.6 1.4 8.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 KZN89282.1 - 0.17 11.4 1.4 26 4.3 0.1 3.2 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 KZN89282.1 - 0.18 11.3 0.8 8.3 5.8 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.8 KZN89282.1 - 0.19 10.4 1.1 7.2 5.1 0.1 2.2 2 0 0 2 2 2 0 TIP49 C-terminus Adeno_IVa2 PF02456.10 KZN89282.1 - 0.2 10.2 0.0 0.44 9.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein Pox_A32 PF04665.7 KZN89282.1 - 0.26 10.5 1.2 4.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Arch_ATPase PF01637.13 KZN89282.1 - 0.27 10.8 0.6 0.72 9.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 KZN89282.1 - 0.63 9.0 0.0 1.3 7.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 KZN89282.1 - 0.91 8.9 5.3 0.85 9.0 0.3 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Gly-rich_Ago1 PF12764.2 KZN89283.1 - 2.2 8.9 4.8 0.26 11.9 0.5 1.5 2 0 0 2 2 2 0 Glycine-rich region of argonaut Polysacc_deac_1 PF01522.16 KZN89284.1 - 5e-22 77.8 0.0 9.7e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Parvo_coat PF00740.13 KZN89284.1 - 0.01 14.8 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2334 PF10096.4 KZN89284.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4110 PF13422.1 KZN89284.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Amidase PF01425.16 KZN89285.1 - 1.9e-94 317.0 0.4 2.4e-94 316.6 0.3 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.13 KZN89286.1 - 2.1e-17 62.8 0.9 4.4e-17 61.8 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN89286.1 - 1.4e-06 28.2 14.3 0.00032 20.8 2.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN89286.1 - 4e-06 26.7 9.8 0.0012 18.9 2.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN89286.1 - 5.7e-05 23.1 1.8 5.7e-05 23.1 1.3 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KZN89286.1 - 0.045 13.9 1.4 0.075 13.2 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.15 KZN89286.1 - 0.12 12.0 0.8 0.22 11.2 0.5 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AAA_12 PF13087.1 KZN89287.1 - 2.1e-41 141.5 0.0 3.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN89287.1 - 5.4e-25 88.3 0.0 2.5e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN89287.1 - 3.1e-09 36.4 0.0 1.6e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN89287.1 - 2.1e-08 34.0 0.0 6.1e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KZN89287.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KZN89287.1 - 0.001 18.6 0.0 0.071 12.6 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KZN89287.1 - 0.0047 16.1 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 KZN89287.1 - 0.033 13.1 0.1 0.51 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KZN89287.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 KZN89287.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KZN89287.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KZN89287.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain WD40 PF00400.27 KZN89288.1 - 3.5e-21 74.2 1.9 0.019 14.8 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Excalibur PF05901.6 KZN89289.1 - 0.45 10.9 2.0 5.3 7.4 0.6 2.6 2 0 0 2 2 2 0 Excalibur calcium-binding domain PRP38 PF03371.10 KZN89290.1 - 4.6e-67 224.9 0.0 5.6e-67 224.6 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF3445 PF11927.3 KZN89291.1 - 3.6e-78 262.4 0.0 4.6e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Bac_rhamnosid_N PF08531.5 KZN89291.1 - 0.014 14.9 0.2 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Zn_clus PF00172.13 KZN89292.1 - 0.00019 21.2 1.8 0.00033 20.4 1.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN89292.1 - 0.0022 16.6 0.5 0.011 14.4 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DBC1 PF14443.1 KZN89292.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 DBC1 RTA1 PF04479.8 KZN89293.1 - 6.2e-47 159.9 8.8 6.2e-47 159.9 6.1 1.4 2 0 0 2 2 2 1 RTA1 like protein DAP10 PF07213.6 KZN89293.1 - 0.25 11.1 1.4 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 DAP10 membrane protein Phage_holin_4 PF05105.7 KZN89293.1 - 5.6 6.6 9.0 0.27 10.9 1.8 2.1 2 1 0 2 2 2 0 Holin family DUF4131 PF13567.1 KZN89293.1 - 7.4 5.9 12.5 0.17 11.2 1.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Oxidored_molyb PF00174.14 KZN89294.1 - 3.2e-47 160.1 0.0 2.1e-46 157.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KZN89294.1 - 1.1e-36 125.3 0.1 2.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KZN89294.1 - 9.6e-25 87.2 0.1 1.3e-23 83.6 0.0 2.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN89294.1 - 5.4e-21 74.5 0.0 3.6e-20 71.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KZN89294.1 - 3.4e-20 71.6 0.1 9.1e-20 70.2 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KZN89294.1 - 0.0018 18.2 1.0 0.015 15.2 0.0 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Sugar_tr PF00083.19 KZN89295.1 - 7.9e-22 77.4 9.5 1.4e-19 70.0 6.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89295.1 - 0.13 10.9 17.3 2.3 6.8 11.9 2.0 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2304 PF10066.4 KZN89295.1 - 1.8 8.4 4.5 2 8.2 0.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pyr_redox_3 PF13738.1 KZN89297.1 - 1.2e-19 71.1 0.0 3.1e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN89297.1 - 1.2e-11 43.4 1.1 1.2e-10 40.2 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN89297.1 - 2e-07 30.2 0.1 5.5e-05 22.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN89297.1 - 3.9e-06 26.7 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89297.1 - 0.002 18.0 0.0 0.016 15.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89297.1 - 0.014 15.1 0.1 0.074 12.8 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 KZN89297.1 - 0.17 10.9 0.0 9.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family WSC PF01822.14 KZN89299.1 - 1.2e-11 44.4 10.1 1.2e-11 44.4 7.0 2.5 2 1 0 2 2 2 1 WSC domain Podoplanin PF05808.6 KZN89299.1 - 0.00078 19.0 14.9 0.0014 18.2 10.3 1.4 1 0 0 1 1 1 1 Podoplanin Rifin_STEVOR PF02009.11 KZN89299.1 - 0.0019 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF2029 PF09594.5 KZN89299.1 - 0.0034 16.9 1.9 0.21 11.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2029) Amnionless PF14828.1 KZN89299.1 - 0.022 13.2 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4328 PF14219.1 KZN89299.1 - 0.11 11.7 0.2 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Adeno_E3_CR2 PF02439.10 KZN89299.1 - 0.15 11.6 1.5 0.32 10.5 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HNH_2 PF13391.1 KZN89300.1 - 6.9e-06 25.7 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease IMS PF00817.15 KZN89301.1 - 3.8e-37 127.3 0.0 2.3e-36 124.8 0.0 2.1 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KZN89301.1 - 6.4e-13 48.7 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DDOST_48kD PF03345.9 KZN89304.1 - 5.7e-167 555.5 0.0 6.4e-167 555.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pilus_PilP PF11356.3 KZN89304.1 - 0.08 13.1 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus biogenesis Abhydrolase_6 PF12697.2 KZN89305.1 - 4.4e-25 88.8 0.3 5.1e-25 88.6 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89305.1 - 9.3e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN89305.1 - 3.9e-05 23.3 0.0 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KZN89305.1 - 0.0022 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.7 KZN89305.1 - 0.0064 16.0 0.1 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF900 PF05990.7 KZN89305.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.6 KZN89305.1 - 0.16 11.3 0.0 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain Pet191_N PF10203.4 KZN89306.1 - 1.7e-29 101.6 4.3 2.1e-29 101.3 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GDNF PF02351.11 KZN89306.1 - 0.025 15.0 1.0 0.035 14.6 0.7 1.2 1 0 0 1 1 1 0 GDNF/GAS1 domain Perm-CXXC PF15629.1 KZN89306.1 - 0.042 13.8 0.2 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Cmc1 PF08583.5 KZN89306.1 - 0.065 13.0 3.2 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 KZN89306.1 - 0.13 11.9 0.6 0.26 10.9 0.2 1.7 2 0 0 2 2 2 0 PAN-like domain Abhydro_lipase PF04083.11 KZN89307.1 - 1.6e-22 78.6 0.3 3.6e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KZN89307.1 - 1.6e-18 67.1 0.2 2.4e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN89307.1 - 2e-07 31.1 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89307.1 - 2.8e-05 23.8 0.0 0.00018 21.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KZN89307.1 - 0.0013 18.2 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Tannase PF07519.6 KZN89309.1 - 6.1e-147 490.1 5.3 7.6e-147 489.8 3.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase SNF2_N PF00176.18 KZN89310.1 - 2.3e-84 282.7 1.2 2.3e-84 282.7 0.8 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KZN89310.1 - 1.4e-24 85.8 0.3 4.2e-24 84.2 0.2 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KZN89310.1 - 2.3e-19 69.0 0.5 9.9e-18 63.7 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 KZN89310.1 - 6.3e-18 64.7 2.8 6.3e-18 64.7 1.9 4.1 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KZN89310.1 - 7.8e-17 60.8 13.6 7.8e-17 60.8 9.4 2.5 2 0 0 2 2 2 1 HSA QLQ PF08880.6 KZN89310.1 - 8.2e-13 47.5 1.3 8.2e-13 47.5 0.9 2.4 2 0 0 2 2 2 1 QLQ M11L PF11099.3 KZN89310.1 - 0.053 13.2 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11L like BAR PF03114.13 KZN89311.1 - 1.6e-47 161.9 5.6 2.1e-47 161.5 3.9 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KZN89311.1 - 2e-06 26.9 2.6 2.6e-06 26.5 1.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF137 PF02006.11 KZN89311.1 - 0.022 14.1 0.2 0.053 12.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF137 APG6 PF04111.7 KZN89311.1 - 3.5 6.6 9.1 5.7 5.8 6.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ada_Zn_binding PF02805.11 KZN89312.1 - 1.3e-28 98.3 5.3 2.1e-28 97.6 3.7 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KZN89312.1 - 1.3e-09 37.5 0.0 2.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KZN89312.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Ribosomal_L2_C PF03947.13 KZN89313.1 - 7.5e-39 132.4 4.1 1.2e-38 131.8 2.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KZN89313.1 - 1.1e-11 44.5 0.1 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM1 PF15612.1 KZN89314.1 - 0.00089 19.0 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 KZN89314.1 - 0.27 9.1 8.8 0.51 8.1 6.1 1.4 1 0 0 1 1 1 0 Nop14-like family WHIM2 PF15613.1 KZN89314.1 - 0.47 10.4 2.7 0.41 10.6 0.4 2.1 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF1770 PF08589.5 KZN89315.1 - 9.1e-27 93.5 0.9 1.7e-26 92.7 0.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.19 KZN89316.1 - 3.7e-65 220.0 0.1 4.3e-65 219.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KZN89316.1 - 0.0022 17.2 0.0 0.0076 15.4 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 KZN89317.1 - 1e-64 218.4 0.7 4.8e-64 216.2 0.0 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KZN89317.1 - 1.4e-20 73.6 0.3 4.1e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KZN89317.1 - 0.073 12.7 0.4 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 TPR repeat zf-C2H2 PF00096.21 KZN89318.1 - 0.061 13.6 0.8 0.061 13.6 0.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN89318.1 - 0.083 13.2 6.4 2.1 8.8 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 KZN89320.1 - 2.2e-67 226.9 0.0 5.8e-67 225.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89320.1 - 5.3e-48 163.3 0.0 2.5e-47 161.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KZN89320.1 - 6.4e-30 103.1 0.0 1.4e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KZN89320.1 - 1.5e-16 60.2 0.0 3.2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KZN89320.1 - 4.1e-14 52.1 0.1 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KZN89320.1 - 5e-07 28.9 0.0 0.00055 18.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 KZN89320.1 - 0.00045 20.6 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain M-inducer_phosp PF06617.8 KZN89320.1 - 0.0026 16.8 0.4 0.0066 15.5 0.3 1.6 1 0 0 1 1 1 1 M-phase inducer phosphatase Kdo PF06293.9 KZN89320.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 KZN89321.1 - 1e-24 86.0 0.0 1.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus UCH_1 PF13423.1 KZN89322.1 - 8.2e-73 245.4 1.3 3.7e-72 243.2 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KZN89322.1 - 8.1e-16 57.9 0.0 3.1e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pep3_Vps18 PF05131.9 KZN89323.1 - 2.3e-43 147.1 0.0 8.6e-43 145.2 0.0 2.0 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KZN89323.1 - 5.6e-08 32.4 3.5 9.8e-05 21.9 0.0 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KZN89323.1 - 0.00078 19.2 0.5 0.0019 18.0 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN89323.1 - 0.0014 18.3 0.2 0.0032 17.1 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN89323.1 - 0.066 12.8 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 KZN89323.1 - 0.11 12.6 0.1 0.38 10.8 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Fungal_trans PF04082.13 KZN89324.1 - 1.2e-10 40.6 1.6 2.1e-10 39.9 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 KZN89326.1 - 6.4e-57 192.6 0.0 9.3e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89326.1 - 7.3e-35 120.2 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN89326.1 - 7.5e-12 44.8 0.0 3.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KZN89326.1 - 0.013 14.5 0.0 0.036 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 KZN89327.1 - 5.9e-33 113.5 0.1 1.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Spo12 PF05032.7 KZN89328.1 - 1.3e-16 59.8 1.2 2.7e-16 58.9 0.8 1.5 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 KZN89329.1 - 3.1e-30 105.2 1.7 5e-30 104.5 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN89329.1 - 1.2e-16 59.9 0.2 3.4e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN89329.1 - 2.6e-15 56.8 2.8 4.4e-15 56.1 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN89329.1 - 2.4e-13 50.6 0.0 5.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain MMR_HSR1 PF01926.18 KZN89330.1 - 2.2e-17 63.0 0.2 1.6e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN89330.1 - 4.5e-07 29.2 0.1 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KZN89330.1 - 0.00032 19.9 0.0 0.00072 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KZN89330.1 - 0.0011 18.7 3.8 0.16 11.7 0.2 3.2 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 KZN89330.1 - 0.0041 16.2 0.0 0.0086 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Glyco_transf_25 PF01755.12 KZN89330.1 - 0.038 13.6 1.4 0.11 12.1 1.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Miro PF08477.8 KZN89330.1 - 0.048 14.1 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein LTV PF04180.9 KZN89331.1 - 1.7e-71 242.0 4.9 5.5e-71 240.2 3.4 1.7 1 1 0 1 1 1 1 Low temperature viability protein DUF2890 PF11081.3 KZN89331.1 - 6.3 6.8 6.9 22 5.0 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) HAD_2 PF13419.1 KZN89332.1 - 5.8e-23 81.9 0.1 7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN89332.1 - 1.9e-07 31.6 0.1 4.2e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN89332.1 - 0.0011 19.1 0.2 0.0015 18.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN89332.1 - 0.0048 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PLDc_2 PF13091.1 KZN89333.1 - 3.1e-15 56.0 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KZN89333.1 - 8.4e-09 34.9 0.5 0.014 15.2 0.4 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif TPR_14 PF13428.1 KZN89334.1 - 1.3e-06 28.4 19.7 4.4 8.2 0.1 8.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN89334.1 - 8.4e-06 25.3 12.6 0.0039 16.8 0.1 5.2 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 KZN89334.1 - 1.4e-05 24.9 14.1 0.11 12.4 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN89334.1 - 0.00012 22.0 1.0 4.2 7.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN89334.1 - 0.0012 18.5 2.5 4.1 7.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN89334.1 - 0.0017 17.8 6.8 2 8.1 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89334.1 - 0.0035 17.1 16.0 3.8 7.6 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89334.1 - 0.015 15.9 21.0 0.91 10.2 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KZN89334.1 - 0.077 13.3 15.0 0.75 10.1 0.3 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat RIX1 PF08167.7 KZN89335.1 - 1.3e-60 203.7 1.1 1.3e-60 203.7 0.8 2.3 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.1 KZN89336.1 - 7.2e-22 77.2 5.4 7.6e-22 77.1 1.9 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family adh_short PF00106.20 KZN89337.1 - 7.3e-28 97.5 0.1 9.4e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89337.1 - 1.1e-18 67.8 0.2 1.4e-18 67.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89337.1 - 9.6e-11 41.6 0.2 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89337.1 - 2e-07 30.7 0.3 3.5e-07 29.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN89337.1 - 0.00027 19.9 0.1 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN89337.1 - 0.0015 18.5 1.0 0.017 15.1 0.7 2.6 1 1 0 1 1 1 1 NADH(P)-binding ACT_7 PF13840.1 KZN89337.1 - 0.0019 17.6 0.9 0.018 14.5 0.0 2.7 3 0 0 3 3 3 1 ACT domain Saccharop_dh PF03435.13 KZN89337.1 - 0.0034 16.4 0.1 0.0048 15.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1776 PF08643.5 KZN89337.1 - 0.016 14.3 0.0 0.11 11.5 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Syntaxin_2 PF14523.1 KZN89337.1 - 0.064 13.2 0.3 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein 2OG-FeII_Oxy PF03171.15 KZN89338.1 - 1.6e-12 47.6 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KZN89338.1 - 2e-08 34.7 0.0 5e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Ribonuc_L-PSP PF01042.16 KZN89339.1 - 1.9e-22 79.2 0.0 2.4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP HpcH_HpaI PF03328.9 KZN89340.1 - 1.9e-34 118.4 0.3 2.5e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 KZN89340.1 - 0.002 17.0 0.1 0.049 12.5 0.0 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain MFS_1 PF07690.11 KZN89341.1 - 2.8e-39 134.8 18.0 2.8e-39 134.8 12.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CopD PF05425.8 KZN89341.1 - 5.8 7.1 9.8 6.2 7.0 2.8 2.8 2 1 0 2 2 2 0 Copper resistance protein D Fungal_trans PF04082.13 KZN89342.1 - 2.2e-15 56.2 0.9 2.2e-15 56.2 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KZN89342.1 - 8.7e-06 25.7 12.4 0.01 16.1 1.4 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN89342.1 - 3.7e-05 23.8 14.0 0.037 14.3 1.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KZN89342.1 - 0.07 13.0 5.3 2.1 8.3 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KZN89342.1 - 0.28 11.4 6.0 8.6 6.7 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.6 KZN89342.1 - 0.86 9.2 6.0 2.1 7.9 0.4 2.6 1 1 1 2 2 2 0 GAGA factor SNF2_N PF00176.18 KZN89343.1 - 3.1e-70 236.3 0.0 4.5e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KZN89343.1 - 1.7e-12 47.1 0.0 4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KZN89343.1 - 7.8e-12 44.9 0.0 1.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KZN89343.1 - 1.7e-10 40.5 9.5 3.9e-10 39.3 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KZN89343.1 - 1e-09 38.2 13.2 1.2e-09 38.0 6.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN89343.1 - 1.5e-09 37.3 8.3 1.5e-09 37.3 5.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN89343.1 - 6.5e-09 35.3 10.2 6.5e-09 35.3 7.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN89343.1 - 3e-07 30.0 8.5 7.4e-07 28.7 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KZN89343.1 - 7.4e-07 28.9 9.3 1.4e-06 28.0 6.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KZN89343.1 - 3.9e-05 23.6 4.0 0.00012 22.0 2.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KZN89343.1 - 0.0016 18.0 5.4 0.0049 16.5 3.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KZN89343.1 - 0.0022 17.4 5.4 0.0049 16.3 3.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KZN89343.1 - 0.025 14.3 3.7 0.06 13.1 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KZN89343.1 - 0.05 13.1 7.6 0.11 12.0 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HDA2-3 PF11496.3 KZN89343.1 - 0.051 12.3 0.1 2.5 6.8 0.0 3.2 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Prok-RING_4 PF14447.1 KZN89343.1 - 0.08 12.4 3.3 0.17 11.4 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 KZN89343.1 - 0.14 12.1 0.4 0.7 9.8 0.0 2.3 3 0 0 3 3 2 0 U-box domain SH3_8 PF13457.1 KZN89344.1 - 1 9.5 3.3 0.48 10.6 0.2 2.0 2 0 0 2 2 2 0 SH3-like domain Fungal_trans_2 PF11951.3 KZN89345.1 - 1.4e-09 37.0 1.5 3.6e-09 35.6 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89345.1 - 0.00075 19.3 6.2 0.0017 18.2 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M11L PF11099.3 KZN89345.1 - 0.039 13.7 0.2 0.69 9.6 0.0 2.6 3 0 0 3 3 3 0 Apoptosis regulator M11L like Transferase PF02458.10 KZN89346.1 - 4e-07 28.8 0.0 5.4e-06 25.1 0.0 2.1 2 1 0 2 2 2 2 Transferase family SNF2_N PF00176.18 KZN89347.1 - 4.1e-45 153.8 0.0 6.7e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN89347.1 - 2e-14 53.1 0.0 4e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN89347.1 - 0.00045 20.0 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SMP_2 PF10144.4 KZN89347.1 - 0.14 11.2 0.1 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin GSH_synth_ATP PF03917.12 KZN89348.1 - 5.6e-100 334.4 0.0 6.8e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KZN89348.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FMN_dh PF01070.13 KZN89349.1 - 1.6e-101 339.7 0.0 2.1e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KZN89349.1 - 5.9e-07 28.7 0.2 0.00068 18.6 0.0 3.0 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KZN89349.1 - 1.5e-06 27.3 0.1 2.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KZN89349.1 - 0.011 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 KZN89349.1 - 0.014 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 KZN89349.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Bestrophin PF01062.16 KZN89350.1 - 5.5e-50 169.9 2.0 1e-48 165.8 1.4 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF876 PF05936.7 KZN89350.1 - 0.086 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) Sugar_tr PF00083.19 KZN89352.1 - 1.1e-89 301.0 20.1 1.4e-89 300.7 13.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89352.1 - 3.2e-13 49.1 42.5 2.8e-10 39.4 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.16 KZN89354.1 - 1.5e-102 342.9 0.0 1.8e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.8 KZN89355.1 - 1.2e-32 111.5 0.3 1.5e-32 111.3 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 KZN89355.1 - 0.046 13.5 0.5 0.061 13.1 0.3 1.2 1 0 0 1 1 1 0 RNHCP domain DNA_ligase_ZBD PF03119.11 KZN89355.1 - 0.078 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF459 PF04311.8 KZN89355.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Metallophos PF00149.23 KZN89356.1 - 6.7e-39 133.3 0.0 9.7e-39 132.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KZN89356.1 - 2.4e-28 97.9 0.2 5.2e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KZN89356.1 - 1.6e-20 72.5 1.3 3.4e-14 52.2 0.0 3.2 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KZN89356.1 - 2.1e-09 36.5 1.9 9.7e-05 21.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89356.1 - 2.6e-09 36.2 2.1 0.034 14.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89356.1 - 1.6e-05 25.4 2.7 0.069 13.8 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN89356.1 - 0.003 17.6 0.5 1.7 9.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN89356.1 - 0.004 16.9 0.1 0.8 9.6 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN89356.1 - 0.0048 17.1 0.3 2.3 8.6 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KZN89356.1 - 0.12 12.3 0.2 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 KZN89356.1 - 0.27 11.9 4.1 43 5.1 0.0 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF89 PF01937.14 KZN89357.1 - 6.5e-120 400.1 0.0 7.2e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.1 KZN89357.1 - 0.14 11.5 0.0 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain Cut12 PF11500.3 KZN89358.1 - 2.4e-47 160.4 5.7 2.4e-47 160.4 4.0 4.6 4 1 1 5 5 5 1 Spindle pole body formation-associated protein FUSC PF04632.7 KZN89358.1 - 1.3 7.3 11.8 2.1 6.6 8.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4267 PF14087.1 KZN89359.1 - 2.9e-34 117.0 3.3 3.4e-34 116.8 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF2892 PF11127.3 KZN89359.1 - 2.9 7.7 6.5 0.48 10.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) HGTP_anticodon2 PF12745.2 KZN89360.1 - 3.8e-82 275.5 2.5 3.8e-82 275.5 1.7 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 KZN89360.1 - 5.6e-66 222.3 0.1 4e-37 127.7 0.0 5.3 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89360.1 - 8.9e-37 126.5 0.0 7e-19 67.9 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 KZN89360.1 - 1.4e-14 53.8 0.0 5.3e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 KZN89360.1 - 3.3e-14 52.6 1.6 7.6e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 KZN89360.1 - 0.00019 21.2 5.9 0.0015 18.3 0.0 3.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN89360.1 - 0.0017 17.3 0.0 0.36 9.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.15 KZN89360.1 - 0.0068 16.3 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF3455 PF11937.3 KZN89361.1 - 0.045 13.6 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) TPR_10 PF13374.1 KZN89361.1 - 2.1 8.3 5.7 3.8 7.5 2.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 KZN89362.1 - 0.00037 20.0 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN89362.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN89362.1 - 0.0028 17.5 0.2 0.0062 16.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN89362.1 - 0.0043 16.7 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.18 KZN89363.1 - 3.3e-19 68.9 0.1 8.6e-19 67.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KZN89363.1 - 1.9e-18 66.0 0.1 4.2e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KZN89363.1 - 1.4e-12 47.1 0.0 2.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KZN89363.1 - 4e-05 23.5 0.2 0.029 14.1 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KZN89363.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KZN89363.1 - 0.02 13.6 0.3 0.061 12.0 0.1 1.8 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 KZN89363.1 - 0.031 13.0 0.0 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AIG1 PF04548.11 KZN89363.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 AIG1 family CPSase_sm_chain PF00988.17 KZN89364.1 - 9.2e-46 154.5 0.0 1.6e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KZN89364.1 - 1.8e-45 154.7 0.0 2.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN89364.1 - 4.1e-06 26.3 0.1 0.0005 19.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase C26 SnoaL PF07366.7 KZN89365.1 - 0.025 14.1 0.2 0.043 13.3 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Fungal_trans PF04082.13 KZN89366.1 - 6.8e-09 34.9 0.0 1.4e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89366.1 - 1.1e-08 34.8 12.4 2e-08 33.9 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 KZN89367.1 - 5.8e-27 93.2 5.9 9.2e-27 92.5 4.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KZN89367.1 - 2.9e-23 81.5 1.0 5.8e-21 74.1 0.0 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain PIG-X PF08320.7 KZN89368.1 - 1.7e-69 233.2 0.0 2.7e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Abhydrolase_3 PF07859.8 KZN89369.1 - 2.8e-40 138.1 0.0 3.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89369.1 - 0.00041 20.1 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN89369.1 - 0.00074 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.23 KZN89369.1 - 0.015 14.0 0.0 0.045 12.4 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family DUF2424 PF10340.4 KZN89369.1 - 0.052 12.1 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S10 PF00450.17 KZN89370.1 - 2.3e-51 175.3 0.3 7.5e-51 173.5 0.2 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.15 KZN89371.1 - 1.1e-35 122.9 0.0 2.5e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.21 KZN89371.1 - 1.8e-06 28.0 0.0 4.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KZN89371.1 - 9.2e-05 22.2 0.1 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain PBP PF01161.15 KZN89372.1 - 3.4e-18 65.9 0.1 3.9e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein p450 PF00067.17 KZN89373.1 - 1.1e-18 66.9 0.0 1.4e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 KZN89374.1 - 3.2e-06 27.0 0.0 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Glyco_hydro_6 PF01341.12 KZN89374.1 - 0.037 13.4 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 DUF500 PF04366.7 KZN89375.1 - 3.4e-44 149.3 0.0 6.5e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) ETF PF01012.16 KZN89376.1 - 9.1e-37 126.2 0.2 1.2e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ribosomal_L20 PF00453.13 KZN89376.1 - 0.036 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 FAD_binding_1 PF00667.15 KZN89377.1 - 1.3e-33 116.2 0.0 2e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KZN89377.1 - 2.2e-29 102.2 0.0 4.1e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KZN89377.1 - 9.1e-15 55.1 0.0 2.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KZN89377.1 - 0.0019 18.2 0.0 0.0059 16.6 0.0 1.7 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KZN89377.1 - 0.0073 15.7 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain FAD_binding_6 PF00970.19 KZN89377.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain RNA_pol_3_Rpc31 PF11705.3 KZN89378.1 - 6.1e-57 193.2 10.7 7.5e-57 192.9 7.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cut8_N PF14482.1 KZN89378.1 - 0.089 12.8 0.1 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Cwf_Cwc_15 PF04889.7 KZN89378.1 - 0.41 10.3 5.3 0.63 9.7 3.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein JAB PF01398.16 KZN89380.1 - 1.9e-07 30.8 0.0 6.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KZN89380.1 - 0.02 14.9 2.4 0.093 12.8 1.6 2.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Solute_trans_a PF03619.11 KZN89381.1 - 3.5e-85 285.6 18.3 4.1e-85 285.4 12.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SAP PF02037.22 KZN89382.1 - 2e-09 36.7 0.2 3.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain Glyco_hydro_67M PF07488.7 KZN89383.1 - 1.7e-151 503.7 0.2 2.4e-151 503.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KZN89383.1 - 9.8e-96 319.5 4.5 1.5e-95 318.9 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KZN89383.1 - 1.7e-33 115.2 0.0 3.1e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KZN89383.1 - 0.0025 18.3 0.0 0.0064 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 BetaGal_dom4_5 PF13364.1 KZN89383.1 - 0.0072 16.5 0.9 0.087 13.0 0.2 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Ribosomal_L7Ae PF01248.21 KZN89384.1 - 3.2e-26 90.6 0.0 3.6e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Abhydrolase_1 PF00561.15 KZN89385.1 - 3.8e-42 144.4 0.0 2.6e-41 141.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN89385.1 - 6.5e-14 52.3 0.9 2.9e-13 50.2 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89385.1 - 0.0084 15.8 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KZN89385.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Glyco_hydro_3 PF00933.16 KZN89387.1 - 1.8e-85 286.5 0.0 2.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN89387.1 - 3.9e-66 222.8 0.0 1.3e-65 221.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN89387.1 - 1.4e-22 79.4 1.7 3.8e-22 77.9 0.8 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KZN89387.1 - 3.6e-15 55.8 0.1 8e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 PA14 domain DUF2808 PF10989.3 KZN89387.1 - 0.1 12.2 0.2 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Tho2 PF11262.3 KZN89388.1 - 4.9e-92 308.1 0.0 8.5e-92 307.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KZN89388.1 - 4.3e-30 103.3 0.2 3.6e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit SAPS PF04499.10 KZN89388.1 - 0.23 10.0 0.2 0.55 8.8 0.1 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_13 PF13166.1 KZN89388.1 - 0.61 8.4 0.3 1.1 7.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.16 KZN89389.1 - 8.5e-11 41.7 0.1 0.00038 19.9 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN89389.1 - 2.7e-06 27.7 0.0 7.1e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KZN89389.1 - 1.5e-05 24.3 0.1 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN89389.1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN89389.1 - 0.095 11.6 0.0 0.99 8.2 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 KZN89389.1 - 0.11 11.2 0.1 1.4 7.5 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFA PF04828.9 KZN89390.1 - 5.9e-19 67.8 0.5 8.9e-19 67.2 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KZN89390.1 - 0.015 14.5 0.1 0.043 13.0 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain MafB19-deam PF14437.1 KZN89390.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase DPBB_1 PF03330.13 KZN89390.1 - 0.4 10.7 2.3 1.8 8.6 1.6 2.1 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Nudix_N_2 PF14803.1 KZN89390.1 - 0.42 10.3 0.1 0.42 10.3 0.1 3.8 4 0 0 4 4 4 0 Nudix N-terminal DiS_P_DiS PF06750.8 KZN89390.1 - 0.49 10.2 0.1 0.49 10.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Vps5 PF09325.5 KZN89391.1 - 2.3e-17 63.0 0.6 3.6e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KZN89391.1 - 1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.22 KZN89392.1 - 2.3e-52 177.1 0.0 3.4e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KZN89392.1 - 2.4e-25 88.1 0.0 5.2e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KZN89392.1 - 3.3e-17 62.1 0.0 2.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KZN89392.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FTHFS PF01268.14 KZN89392.1 - 0.046 11.6 0.0 0.071 11.0 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase MMR_HSR1 PF01926.18 KZN89392.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArfGap PF01412.13 KZN89393.1 - 7.1e-32 109.6 0.1 1.4e-31 108.6 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 KZN89394.1 - 1.1e-31 108.2 0.2 7.8e-15 54.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN89394.1 - 3.6e-22 78.1 0.0 3.3e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN89394.1 - 1.3e-09 37.7 0.1 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KZN89394.1 - 0.071 12.7 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain API5 PF05918.6 KZN89394.1 - 0.25 9.7 2.4 0.41 9.0 1.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2985 PF11204.3 KZN89395.1 - 2.5e-29 100.8 4.3 3e-29 100.5 2.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF3328 PF11807.3 KZN89395.1 - 7.3 6.2 6.8 2 8.0 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) NAD_binding_10 PF13460.1 KZN89396.1 - 1.2e-05 25.4 0.0 0.0055 16.7 0.0 2.7 2 2 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 KZN89396.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Hydrophobin PF01185.13 KZN89397.1 - 1.4e-14 54.3 8.0 1.8e-14 53.9 5.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ub-RnfH PF03658.9 KZN89397.1 - 0.12 12.2 0.1 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 RnfH family Ubiquitin SMI1_KNR4 PF09346.5 KZN89398.1 - 0.0085 16.0 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PAD_porph PF04371.10 KZN89399.1 - 1.6e-68 231.2 0.0 2e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Orn_Arg_deC_N PF02784.11 KZN89400.1 - 9.8e-61 205.1 0.0 1.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KZN89400.1 - 7.4e-25 86.9 0.1 1.2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CinA PF02464.12 KZN89400.1 - 0.11 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Competence-damaged protein Opi1 PF08618.5 KZN89401.1 - 1.3e-97 327.4 0.4 5.1e-55 187.1 1.9 3.5 1 1 2 3 3 3 3 Transcription factor Opi1 RdRP PF05183.7 KZN89402.1 - 2.7e-121 406.0 0.0 4.5e-121 405.3 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase WXG100 PF06013.7 KZN89402.1 - 0.24 11.3 1.2 0.61 10.1 0.9 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Sugar_tr PF00083.19 KZN89403.1 - 1.7e-07 30.2 0.2 1.9e-07 30.0 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PRELI PF04707.9 KZN89406.1 - 2.5e-24 85.6 0.0 1.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family NmrA PF05368.8 KZN89407.1 - 1.1e-29 103.4 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN89407.1 - 2.2e-13 50.6 0.0 4e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KZN89407.1 - 1.6e-06 27.4 0.1 2.1e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KZN89407.1 - 0.00032 20.9 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KZN89407.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KZN89407.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KZN89407.1 - 0.063 13.1 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KZN89407.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4301 PF14134.1 KZN89407.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) DUF1612 PF07756.7 KZN89408.1 - 0.04 13.9 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Prenyltrans PF00432.16 KZN89408.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat KCNQC3-Ank-G_bd PF11956.3 KZN89409.1 - 0.0041 17.1 0.3 0.0066 16.4 0.2 1.3 1 0 0 1 1 1 1 Ankyrin-G binding motif of KCNQ2-3 PSI_8 PF00796.13 KZN89409.1 - 0.24 10.9 1.6 0.44 10.1 1.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII adh_short_C2 PF13561.1 KZN89410.1 - 5.2e-25 88.6 0.3 6.7e-25 88.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN89410.1 - 4e-23 82.1 2.8 6.2e-23 81.5 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN89410.1 - 1.1e-08 34.9 4.4 6.1e-08 32.5 3.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89410.1 - 0.0029 17.0 1.5 0.025 14.0 1.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KZN89410.1 - 0.0043 16.2 0.7 0.012 14.7 0.2 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN89410.1 - 0.012 16.0 1.4 0.024 15.0 1.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KZN89410.1 - 0.025 14.3 1.3 0.055 13.1 0.5 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KZN89410.1 - 0.049 13.2 1.4 0.082 12.5 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 KZN89410.1 - 0.05 13.2 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.14 KZN89410.1 - 0.068 12.2 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 KZN89410.1 - 0.098 12.0 0.2 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KZN89410.1 - 0.12 12.4 0.4 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Voldacs PF03517.8 KZN89412.1 - 2.2e-30 105.2 0.2 1.1e-29 103.0 0.1 2.1 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Nse5 PF08691.5 KZN89413.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Fungal_trans_2 PF11951.3 KZN89414.1 - 8.5e-35 120.0 0.1 1.8e-34 119.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89414.1 - 3.4e-08 33.2 9.4 6.1e-08 32.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27_GFWDK PF10347.4 KZN89414.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CM_2 PF01817.16 KZN89415.1 - 2.6e-12 46.6 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Chorismate mutase type II CENP-H PF05837.7 KZN89415.1 - 0.021 15.0 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.6 KZN89415.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Nucleic_acid_bd PF13820.1 KZN89415.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative nucleic acid-binding region adh_short_C2 PF13561.1 KZN89416.1 - 1.8e-34 119.5 0.0 2.3e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN89416.1 - 2.3e-29 102.4 0.0 2.8e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN89416.1 - 6e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89416.1 - 0.027 13.9 0.3 0.072 12.5 0.0 1.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 KZN89416.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Eno-Rase_NADH_b PF12242.3 KZN89416.1 - 0.086 12.6 0.6 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dyp_perox PF04261.7 KZN89418.1 - 4.5e-10 38.7 0.1 1.1e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 Dyp-type peroxidase family DUF1929 PF09118.6 KZN89419.1 - 1.6e-24 85.8 0.0 3.9e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KZN89419.1 - 8.4e-17 60.5 3.3 0.00059 19.9 0.1 4.6 4 0 0 4 4 4 3 Kelch motif F5_F8_type_C PF00754.20 KZN89419.1 - 7.5e-16 58.1 0.3 2.1e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Kelch_1 PF01344.20 KZN89419.1 - 2.5e-13 49.3 2.9 0.00039 19.9 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KZN89419.1 - 1.3e-12 47.2 10.1 0.0013 18.4 0.2 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 KZN89419.1 - 9.1e-12 44.5 0.5 9.4e-09 34.6 0.2 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 KZN89419.1 - 9.6e-08 31.5 0.4 0.6 9.9 0.0 5.3 5 0 0 5 5 4 2 Kelch motif Kelch_3 PF13415.1 KZN89419.1 - 0.00055 20.0 2.1 3.5 7.8 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain APC10 PF03256.11 KZN89419.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) XRCC1_N PF01834.11 KZN89419.1 - 0.07 12.6 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Kelch_5 PF13854.1 KZN89419.1 - 0.081 12.9 8.1 11 6.0 0.1 4.5 4 0 0 4 4 4 0 Kelch motif DUF3472 PF11958.3 KZN89420.1 - 6.3e-13 49.4 0.1 8.5e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Aldo_ket_red PF00248.16 KZN89421.1 - 3.6e-70 236.0 0.0 4.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family But2 PF09792.4 KZN89422.1 - 0.087 12.5 4.0 0.15 11.8 0.2 2.4 2 1 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain DUF1996 PF09362.5 KZN89423.1 - 5e-79 265.2 0.1 5e-79 265.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) AIP3 PF03915.8 KZN89423.1 - 0.063 12.1 0.1 0.091 11.6 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Ribosomal_S26e PF01283.14 KZN89424.1 - 0.098 12.8 0.3 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S26e Metallophos PF00149.23 KZN89425.1 - 3.3e-42 144.1 0.4 4.8e-42 143.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Beta-lactamase PF00144.19 KZN89426.1 - 5.3e-40 137.4 0.0 1e-39 136.5 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF1993 PF09351.5 KZN89427.1 - 5.9e-46 156.3 0.0 6.8e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) UBN2_3 PF14244.1 KZN89428.1 - 0.0018 17.8 0.7 0.0032 17.0 0.5 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BCS1_N PF08740.6 KZN89429.1 - 3.2e-30 105.1 0.1 4.5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KZN89429.1 - 3.2e-20 72.6 0.0 9.7e-20 71.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN89429.1 - 0.00087 20.1 0.0 0.0027 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KZN89429.1 - 0.0036 16.7 0.0 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN89429.1 - 0.0092 15.7 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KZN89429.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 KZN89429.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KZN89429.1 - 0.033 14.1 0.1 0.13 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 KZN89429.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 KZN89429.1 - 0.046 12.8 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Polyoma_lg_T_C PF06431.6 KZN89429.1 - 0.052 12.1 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_29 PF13555.1 KZN89429.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KZN89429.1 - 0.074 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KZN89429.1 - 0.082 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 KZN89429.1 - 0.096 12.8 0.2 0.95 9.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 KZN89429.1 - 0.1 12.4 0.7 0.36 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KZN89429.1 - 0.12 12.3 0.1 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KZN89429.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 KZN89429.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KZN89429.1 - 0.18 12.1 0.1 0.5 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KZN89430.1 - 2.7e-34 118.4 22.4 3.7e-34 117.9 15.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YgaB PF14182.1 KZN89431.1 - 0.034 14.3 1.8 0.078 13.2 1.3 1.5 1 0 0 1 1 1 0 YgaB-like protein DUF3716 PF12511.3 KZN89433.1 - 1.9e-14 52.9 5.6 2.6e-14 52.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AA_permease_2 PF13520.1 KZN89434.1 - 4.6e-43 147.3 52.8 5.7e-43 147.0 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN89434.1 - 1.4e-17 63.2 44.4 2e-17 62.7 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.14 KZN89434.1 - 0.036 13.5 0.2 0.036 13.5 0.2 3.2 5 0 0 5 5 5 0 VIT family PNTB PF02233.11 KZN89435.1 - 9.6e-166 552.1 22.6 1.6e-165 551.3 15.7 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KZN89435.1 - 5.8e-55 185.3 0.5 1.1e-54 184.4 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KZN89435.1 - 1.5e-44 151.3 0.0 3.5e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KZN89435.1 - 1.3e-30 105.3 4.3 1.3e-30 105.3 3.0 4.5 3 1 0 4 4 4 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KZN89435.1 - 3.8e-05 22.9 0.1 0.23 10.6 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 KZN89435.1 - 0.0015 18.3 0.3 0.0096 15.6 0.2 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Methyltransf_31 PF13847.1 KZN89435.1 - 0.0061 16.1 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89435.1 - 0.0092 16.5 0.0 0.035 14.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KZN89435.1 - 0.01 15.3 0.2 0.038 13.5 0.1 2.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KZN89435.1 - 0.019 14.8 0.3 0.071 12.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89435.1 - 0.32 11.0 2.9 0.41 10.7 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KZN89435.1 - 1.3 9.1 6.6 9.3 6.3 0.0 3.9 5 0 0 5 5 4 0 Shikimate / quinate 5-dehydrogenase ELO PF01151.13 KZN89437.1 - 7.8e-62 208.8 24.2 9.1e-62 208.6 16.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.7 KZN89437.1 - 7.3 6.8 11.7 2.2 8.5 2.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1240) COX5A PF02284.11 KZN89438.1 - 1.8e-37 127.6 0.2 2.7e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Glyco_transf_15 PF01793.11 KZN89439.1 - 9.8e-137 455.3 7.7 1.2e-136 455.0 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_25 PF01755.12 KZN89439.1 - 0.0038 16.9 0.5 0.0052 16.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Spc97_Spc98 PF04130.8 KZN89440.1 - 2.7e-71 240.5 8.2 4.6e-71 239.7 5.7 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KZN89440.1 - 1.2e-11 43.5 0.0 3.5e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 tRNA-synt_1b PF00579.20 KZN89441.1 - 7.4e-53 179.5 0.0 9.3e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) GATase_5 PF13507.1 KZN89442.1 - 1.1e-95 319.4 0.0 1.7e-95 318.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KZN89442.1 - 5.6e-44 149.8 0.3 1.1e-20 74.1 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KZN89442.1 - 3e-27 94.6 0.1 1.3e-26 92.6 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Fungal_trans PF04082.13 KZN89443.1 - 3.1e-29 101.6 0.4 6.2e-29 100.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89443.1 - 1.4e-09 37.7 11.3 2.4e-09 36.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCSMST1 PF15013.1 KZN89443.1 - 0.066 13.1 0.0 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 CCSMST1 family DHDPS PF00701.17 KZN89444.1 - 1.6e-39 135.2 0.0 1.9e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank_2 PF12796.2 KZN89445.1 - 2.5e-69 229.6 14.0 2.5e-15 56.6 0.0 6.1 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89445.1 - 1.5e-44 147.6 27.4 0.00031 20.4 0.1 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KZN89445.1 - 5.6e-38 128.6 1.1 5.6e-07 29.9 0.1 8.4 2 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN89445.1 - 2.7e-31 104.4 16.2 0.0067 16.5 0.0 13.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 KZN89445.1 - 8.2e-21 73.5 15.6 0.13 12.5 0.0 11.9 5 3 8 13 13 13 6 Ankyrin repeats (many copies) NACHT PF05729.7 KZN89445.1 - 1.4e-11 44.3 0.1 3.4e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN89445.1 - 8.3e-06 25.9 0.5 4.5e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KZN89445.1 - 8e-05 22.7 0.4 0.00035 20.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KZN89445.1 - 0.0019 17.9 0.0 0.007 16.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain KAP_NTPase PF07693.9 KZN89445.1 - 0.0037 16.3 0.0 0.19 10.6 0.1 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA_11 PF13086.1 KZN89445.1 - 0.019 14.5 0.1 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KZN89445.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 KZN89445.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Wbp11 PF09429.5 KZN89445.1 - 0.19 11.7 0.6 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 WW domain binding protein 11 Cyanate_lyase PF02560.9 KZN89446.1 - 6.9e-32 108.8 0.0 1.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KZN89446.1 - 0.0089 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Homeobox PF00046.24 KZN89446.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Homeobox domain zf-C2H2 PF00096.21 KZN89447.1 - 0.0002 21.5 19.8 0.066 13.5 0.0 5.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN89447.1 - 0.0025 18.0 17.6 0.13 12.6 0.1 5.7 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KZN89447.1 - 0.0026 17.6 5.4 0.034 14.0 0.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger Laminin_I PF06008.9 KZN89447.1 - 0.035 13.4 0.0 0.075 12.3 0.0 1.6 1 1 0 1 1 1 0 Laminin Domain I Laminin_II PF06009.7 KZN89447.1 - 0.25 11.0 4.4 0.69 9.6 0.4 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF2580 PF10824.3 KZN89447.1 - 0.86 9.9 9.6 1.1 9.7 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) zf-C2H2_2 PF12756.2 KZN89447.1 - 2.4 8.3 22.1 0.8 9.8 0.4 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF3619 PF12279.3 KZN89449.1 - 0.036 14.1 1.1 0.066 13.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) OmpH PF03938.9 KZN89449.1 - 0.28 11.1 3.3 0.39 10.6 2.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4278 PF14105.1 KZN89450.1 - 0.23 11.4 4.5 3.5 7.6 1.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4278) DNA_pol_B PF00136.16 KZN89451.1 - 1.5e-145 485.5 3.2 2.4e-145 484.9 2.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KZN89451.1 - 1.6e-80 270.3 0.0 3.5e-80 269.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KZN89451.1 - 6.5e-24 83.7 6.5 1.5e-23 82.5 4.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KZN89451.1 - 0.00076 19.3 0.6 0.0041 16.9 0.4 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KZN89451.1 - 0.0099 15.4 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase PF00069.20 KZN89452.1 - 1.3e-37 129.3 0.0 2.1e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89452.1 - 8.5e-17 61.0 0.0 6.1e-07 28.7 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase DUF3827 PF12877.2 KZN89452.1 - 1.4 6.9 6.6 2.6 6.0 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Acyl-CoA_dh_1 PF00441.19 KZN89453.1 - 1.6e-29 102.9 0.4 2.4e-29 102.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN89453.1 - 8.6e-23 79.6 0.5 1.6e-22 78.7 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KZN89453.1 - 2.5e-21 76.3 0.0 6.1e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KZN89453.1 - 0.0015 18.7 0.2 0.0031 17.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1237 PF06824.6 KZN89454.1 - 6.1e-181 601.6 0.1 7.1e-181 601.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) C2 PF00168.25 KZN89454.1 - 0.016 15.0 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 C2 domain CDC27 PF09507.5 KZN89455.1 - 3.2e-109 366.0 25.4 3.7e-109 365.8 17.6 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.1 KZN89456.1 - 1.9e-09 37.3 17.7 4.1e-08 33.1 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN89456.1 - 2e-08 33.7 16.6 1.3e-07 31.1 9.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN89456.1 - 3.9e-08 32.9 15.3 8e-07 28.7 8.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KZN89456.1 - 1.7e-07 30.8 17.4 5.8e-07 29.1 9.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN89456.1 - 3.5e-07 29.7 14.0 1.1e-06 28.2 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KZN89456.1 - 2.8e-06 27.0 4.8 2.8e-06 27.0 3.3 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KZN89456.1 - 4.5e-05 23.2 12.8 4.5e-05 23.2 8.9 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING SAP PF02037.22 KZN89456.1 - 7.1e-05 22.2 0.0 0.00017 20.9 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.1 KZN89456.1 - 0.00048 19.7 12.9 0.002 17.8 6.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Mob_synth_C PF06463.8 KZN89456.1 - 0.0007 19.2 2.1 0.002 17.8 1.5 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 KZN89456.1 - 0.0036 17.3 8.3 0.0053 16.8 4.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 KZN89456.1 - 0.0055 16.6 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 KZN89456.1 - 0.0069 15.9 12.7 0.032 13.7 7.0 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KZN89456.1 - 0.023 14.5 2.9 0.065 13.0 2.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FAM104 PF15434.1 KZN89456.1 - 0.81 9.9 8.1 0.35 11.1 1.3 2.4 2 0 0 2 2 2 0 Family 104 Snf7 PF03357.16 KZN89457.1 - 4.1e-16 58.8 10.3 4.1e-16 58.8 7.1 1.8 1 1 1 2 2 2 1 Snf7 UME PF08064.8 KZN89457.1 - 0.075 12.9 0.4 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 UME (NUC010) domain NPV_P10 PF05531.7 KZN89457.1 - 0.077 13.2 2.5 14 6.0 1.7 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HAUS-augmin3 PF14932.1 KZN89457.1 - 0.27 10.3 11.7 0.18 10.9 1.6 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 KZN89457.1 - 0.52 10.1 8.2 3.3 7.5 3.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TRAPPC-Trs85 PF12739.2 KZN89458.1 - 1.2e-120 402.9 0.1 1.8e-120 402.4 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 KZN89458.1 - 0.23 10.5 0.7 4 6.4 0.1 2.9 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP PolyA_pol PF01743.15 KZN89459.1 - 1.6e-20 73.5 1.6 8.6e-20 71.2 1.1 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KZN89459.1 - 9.3e-07 28.3 0.1 2.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KZN89459.1 - 0.00032 20.5 0.1 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 KZN89460.1 - 4.1e-90 301.6 1.4 5.4e-90 301.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 KZN89461.1 - 6.1e-95 317.6 0.0 1.3e-94 316.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Ank_2 PF12796.2 KZN89462.1 - 3.7e-81 267.5 0.1 9.3e-17 61.1 0.0 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89462.1 - 9.8e-39 129.2 5.5 9.2e-05 22.0 0.0 9.9 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 KZN89462.1 - 3.9e-36 122.2 0.2 4.1e-05 23.6 0.0 8.4 2 2 7 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN89462.1 - 2.2e-35 120.3 0.1 2.2e-08 34.3 0.0 6.2 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN89462.1 - 6.1e-30 100.2 0.1 0.00035 20.5 0.0 10.0 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.7 KZN89462.1 - 7.2e-07 29.0 0.3 3.9e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KZN89462.1 - 0.0001 22.3 0.1 0.00055 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KZN89462.1 - 0.0037 17.1 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KZN89462.1 - 0.017 15.2 0.2 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KZN89462.1 - 0.033 13.6 0.0 0.15 11.4 0.0 2.3 1 1 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 KZN89462.1 - 0.039 13.4 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RuvC PF02075.12 KZN89462.1 - 0.15 11.9 0.1 0.46 10.3 0.1 1.8 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC HNH_2 PF13391.1 KZN89463.1 - 7.9e-08 31.9 0.0 1.9e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease Pex2_Pex12 PF04757.9 KZN89464.1 - 3.1e-57 193.6 1.7 3.9e-57 193.3 1.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KZN89464.1 - 9.7e-06 25.3 2.2 1.7e-05 24.5 1.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KZN89464.1 - 1.6e-05 24.7 4.0 1.9e-05 24.6 1.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN89464.1 - 0.0027 17.4 1.8 0.0027 17.4 1.3 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KZN89464.1 - 0.018 14.7 1.6 0.031 13.9 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN89464.1 - 0.029 14.0 1.9 0.051 13.2 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Oligomerisation PF02410.10 KZN89465.1 - 9.1e-06 25.6 0.0 8e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 Oligomerisation domain NMD3 PF04981.8 KZN89466.1 - 2.2e-71 239.6 6.4 2.2e-71 239.6 4.4 1.5 2 0 0 2 2 2 1 NMD3 family AF1Q PF15017.1 KZN89466.1 - 0.98 9.3 0.0 0.98 9.3 0.0 3.0 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator DUF1003 PF06210.6 KZN89466.1 - 2.2 8.2 4.7 4.6 7.1 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nop14 PF04147.7 KZN89468.1 - 7.9e-05 20.7 5.5 7.9e-05 20.7 3.8 1.5 2 0 0 2 2 2 1 Nop14-like family DUF2735 PF10931.3 KZN89468.1 - 0.24 11.6 1.2 0.97 9.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) CDC45 PF02724.9 KZN89468.1 - 3.4 5.5 14.4 0.0098 13.9 2.7 1.8 2 0 0 2 2 2 0 CDC45-like protein Mito_carr PF00153.22 KZN89469.1 - 5.8e-63 208.6 1.2 5.2e-22 77.3 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein WAC_Acf1_DNA_bd PF10537.4 KZN89470.1 - 4.4e-41 139.1 0.1 1.9e-40 137.1 0.1 2.2 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KZN89470.1 - 4.8e-19 67.8 1.6 1.2e-18 66.5 1.1 1.7 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KZN89470.1 - 1e-08 34.7 0.2 2.1e-08 33.7 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 KZN89470.1 - 3.6e-05 23.4 0.3 0.00011 21.8 0.2 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 KZN89470.1 - 0.0001 22.0 0.1 0.00064 19.5 0.1 2.4 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.10 KZN89471.1 - 3.6e-141 471.2 32.8 5.1e-141 470.7 22.8 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KZN89472.1 - 2.1e-28 99.0 0.0 3.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF3508 PF12018.3 KZN89472.1 - 0.013 14.5 2.3 0.018 14.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) FadA PF09403.5 KZN89472.1 - 0.072 13.1 2.0 0.13 12.2 1.4 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Perilipin PF03036.11 KZN89472.1 - 0.14 10.9 1.6 0.2 10.4 1.1 1.1 1 0 0 1 1 1 0 Perilipin family PHD PF00628.24 KZN89473.1 - 2.1e-17 62.5 24.4 1.4e-10 40.6 7.4 2.6 2 0 0 2 2 2 2 PHD-finger zf-RanBP PF00641.13 KZN89473.1 - 0.026 13.6 0.2 0.026 13.6 0.2 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_1 PF00130.17 KZN89473.1 - 0.078 12.7 14.2 0.24 11.1 2.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KZN89473.1 - 0.11 12.2 19.6 0.57 9.9 3.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KZN89473.1 - 0.34 10.2 16.3 0.27 10.6 0.2 3.4 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.19 KZN89474.1 - 4.6e-11 42.6 0.0 6.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 KZN89475.1 - 1.4e-10 41.5 0.1 2e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 KZN89476.1 - 6.3e-77 258.3 0.8 1e-76 257.6 0.5 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 KZN89477.1 - 9e-08 32.2 2.7 1.3e-05 25.3 0.2 5.4 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KZN89477.1 - 0.0003 20.6 12.7 0.042 13.9 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Proteasom_PSMB PF10508.4 KZN89477.1 - 0.0085 14.4 0.1 0.087 11.0 0.0 2.6 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 KZN89477.1 - 0.031 14.7 6.3 0.98 9.9 0.1 4.8 5 0 0 5 5 5 0 HEAT-like repeat MFS_1 PF07690.11 KZN89478.1 - 3.1e-39 134.6 43.0 3.1e-39 134.6 29.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2129 PF09902.4 KZN89478.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) AAA PF00004.24 KZN89479.1 - 1.4e-97 322.9 0.0 2.4e-47 160.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KZN89479.1 - 4.7e-20 71.3 0.8 1.4e-19 69.8 0.3 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KZN89479.1 - 2.1e-14 53.7 0.0 8.8e-08 32.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KZN89479.1 - 8.5e-14 51.1 0.1 7.4e-06 25.1 0.0 3.2 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KZN89479.1 - 3.2e-13 49.7 0.0 6.2e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KZN89479.1 - 2.2e-12 46.8 0.5 5.4e-06 26.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN89479.1 - 9.5e-12 45.1 0.2 0.0018 18.3 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN89479.1 - 2.3e-11 44.5 0.0 0.0005 20.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN89479.1 - 6.2e-11 42.6 0.0 0.0019 18.2 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KZN89479.1 - 3e-09 36.1 0.1 0.00093 18.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 KZN89479.1 - 8.2e-09 34.9 0.0 1.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 KZN89479.1 - 2.6e-08 33.7 0.0 0.0035 17.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 KZN89479.1 - 2.8e-08 33.4 4.5 0.027 13.8 0.0 4.6 3 2 1 5 5 4 2 AAA domain IstB_IS21 PF01695.12 KZN89479.1 - 5.9e-08 32.3 0.0 0.0053 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KZN89479.1 - 1.1e-07 31.2 0.6 0.0085 15.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KZN89479.1 - 1.3e-07 30.8 0.0 0.0075 15.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KZN89479.1 - 1.6e-07 31.0 1.3 0.0083 15.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KZN89479.1 - 4.9e-07 29.8 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 KZN89479.1 - 1.7e-06 27.3 1.0 0.45 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 KZN89479.1 - 2.9e-06 27.2 0.0 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KZN89479.1 - 5.1e-06 26.8 0.0 0.085 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KZN89479.1 - 5.8e-06 26.0 0.0 0.095 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN89479.1 - 5.9e-06 26.3 0.0 0.09 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 KZN89479.1 - 8.3e-06 24.9 0.0 0.011 14.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KZN89479.1 - 1.2e-05 25.1 0.0 4.3 6.9 0.0 4.2 2 2 2 4 4 4 0 Archaeal ATPase Parvo_NS1 PF01057.12 KZN89479.1 - 1.3e-05 24.2 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KZN89479.1 - 2.6e-05 23.7 0.1 0.3 10.5 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KZN89479.1 - 3.7e-05 23.4 0.1 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 KZN89479.1 - 5e-05 23.1 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 KZN89479.1 - 6.3e-05 23.0 0.0 0.33 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 KZN89479.1 - 7.5e-05 22.4 0.0 0.51 9.9 0.0 3.2 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.22 KZN89479.1 - 0.00012 22.3 0.0 0.47 10.7 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 KZN89479.1 - 0.00015 21.0 0.4 0.52 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 KZN89479.1 - 0.00015 21.3 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KZN89479.1 - 0.00027 20.5 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KZN89479.1 - 0.00071 19.2 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KZN89479.1 - 0.0011 18.6 0.5 0.65 9.6 0.0 4.0 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 KZN89479.1 - 0.0013 17.8 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KZN89479.1 - 0.0016 17.4 0.2 0.64 8.8 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 KZN89479.1 - 0.0032 17.0 0.0 0.29 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KZN89479.1 - 0.0062 16.0 0.6 1.6 8.0 0.0 3.7 3 1 0 4 4 4 1 AAA-like domain KAP_NTPase PF07693.9 KZN89479.1 - 0.0078 15.2 0.2 0.92 8.4 0.0 3.2 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 KZN89479.1 - 0.014 14.5 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 KZN89479.1 - 0.047 13.1 1.1 12 5.3 0.1 4.1 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) SKI PF01202.17 KZN89479.1 - 0.068 13.0 0.1 8.1 6.2 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 KZN89479.1 - 0.071 11.8 0.0 8.4 5.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase MobB PF03205.9 KZN89479.1 - 0.087 12.5 0.2 3.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KZN89479.1 - 0.089 12.4 0.1 9.2 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 KZN89479.1 - 0.16 11.1 0.4 11 5.1 0.0 2.7 3 0 0 3 3 2 0 Chromatin associated protein KTI12 PEX11 PF05648.9 KZN89480.1 - 1e-12 47.7 0.0 4.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mpv17_PMP22 PF04117.7 KZN89482.1 - 2.8e-14 52.5 0.6 2.5e-12 46.2 0.4 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.10 KZN89483.1 - 4e-32 110.8 0.7 6.8e-32 110.0 0.5 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KZN89483.1 - 6.3e-09 35.2 0.0 1.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UPF0113 PF03657.8 KZN89484.1 - 2.2e-07 30.6 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KZN89484.1 - 9.3e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain NOC3p PF07540.6 KZN89485.1 - 5.3e-32 109.9 0.3 5.3e-32 109.9 0.2 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 KZN89485.1 - 5.6e-32 110.4 1.0 1.4e-31 109.1 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family WEMBL PF05701.6 KZN89486.1 - 0.00015 20.4 5.8 0.00025 19.6 4.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tektin PF03148.9 KZN89486.1 - 0.0012 17.4 2.4 0.0012 17.4 1.7 1.7 2 0 0 2 2 1 1 Tektin family GAS PF13851.1 KZN89486.1 - 0.0013 17.9 8.1 0.002 17.3 4.7 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.4 KZN89486.1 - 0.0019 17.5 12.2 0.11 11.7 0.5 2.1 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) TBPIP PF07106.8 KZN89486.1 - 0.0025 17.3 6.1 0.0025 17.3 3.1 1.8 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 KZN89486.1 - 0.0026 15.5 14.3 0.013 13.3 9.9 1.8 1 1 0 1 1 1 1 Myosin tail V_ATPase_I PF01496.14 KZN89486.1 - 0.0034 15.3 6.1 0.0048 14.8 4.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 KZN89486.1 - 0.0038 15.7 4.0 0.0058 15.1 2.8 1.3 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 KZN89486.1 - 0.0048 14.3 5.9 0.0068 13.8 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 KZN89486.1 - 0.0055 16.4 11.8 0.18 11.5 3.4 3.3 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Cast PF10174.4 KZN89486.1 - 0.0065 14.5 7.0 0.01 13.9 4.9 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2730 PF10805.3 KZN89486.1 - 0.0066 16.1 0.7 0.017 14.8 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Spc7 PF08317.6 KZN89486.1 - 0.0084 14.8 9.3 0.0077 14.9 5.4 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein HAUS-augmin3 PF14932.1 KZN89486.1 - 0.0088 15.2 1.7 0.016 14.3 1.2 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.17 KZN89486.1 - 0.01 15.8 7.0 0.01 15.8 4.9 2.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.10 KZN89486.1 - 0.013 15.6 3.2 0.051 13.7 2.2 2.0 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus IFT57 PF10498.4 KZN89486.1 - 0.013 14.2 3.1 0.022 13.4 2.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 USP8_interact PF08941.5 KZN89486.1 - 0.015 14.6 3.0 1.3 8.3 0.2 2.2 2 0 0 2 2 2 0 USP8 interacting YgaB PF14182.1 KZN89486.1 - 0.025 14.8 0.2 1.1 9.5 0.9 2.6 2 0 0 2 2 2 0 YgaB-like protein Sec2p PF06428.6 KZN89486.1 - 0.025 14.4 3.7 0.79 9.6 0.9 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF677 PF05055.7 KZN89486.1 - 0.039 12.6 1.9 0.045 12.4 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) NPV_P10 PF05531.7 KZN89486.1 - 0.043 14.0 4.6 0.15 12.2 0.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.1 KZN89486.1 - 0.043 14.1 1.3 0.066 13.5 0.9 1.3 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KZN89486.1 - 0.044 13.5 4.7 0.043 13.5 0.7 2.3 1 1 1 2 2 2 0 Laminin Domain II Spore_GerAC PF05504.6 KZN89486.1 - 0.044 13.5 2.6 4.3 7.0 0.0 2.3 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal YvrJ PF12841.2 KZN89486.1 - 0.079 12.2 0.5 6.4 6.1 0.0 2.6 2 0 0 2 2 2 0 YvrJ protein family CAF1 PF04857.15 KZN89486.1 - 0.083 12.2 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF948 PF06103.6 KZN89486.1 - 0.091 12.6 4.2 0.099 12.5 0.2 2.8 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 KZN89486.1 - 0.094 11.7 5.9 0.15 11.0 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 KZN89486.1 - 0.099 12.0 10.8 0.37 10.2 7.4 1.7 1 1 0 1 1 1 0 Intermediate filament protein DUF342 PF03961.8 KZN89486.1 - 0.11 10.9 2.9 0.16 10.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sec8_exocyst PF04048.9 KZN89486.1 - 0.13 11.9 1.5 0.25 10.9 1.1 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.4 KZN89486.1 - 0.14 12.0 12.1 0.03 14.1 5.7 1.8 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.8 KZN89486.1 - 0.14 12.0 6.3 0.34 10.8 4.4 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.7 KZN89486.1 - 0.16 11.8 0.5 0.67 9.7 0.3 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.1 KZN89486.1 - 0.2 10.9 9.4 0.11 11.7 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) PEARLI-4 PF05278.7 KZN89486.1 - 0.25 10.6 5.3 0.44 9.8 3.7 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF3373 PF11853.3 KZN89486.1 - 0.26 9.7 1.0 0.42 9.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TMF_TATA_bd PF12325.3 KZN89486.1 - 0.44 10.2 11.8 6.1 6.6 0.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KZN89486.1 - 0.49 10.2 11.4 2.1 8.2 2.6 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KZN89486.1 - 0.73 9.3 9.2 0.049 13.1 1.0 2.7 3 1 0 3 3 3 0 Septum formation initiator CENP-Q PF13094.1 KZN89486.1 - 0.97 9.4 9.3 0.63 10.0 3.6 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 KZN89486.1 - 0.97 8.3 9.6 2.8 6.7 6.5 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KZN89486.1 - 1 9.7 8.1 1.8 8.9 1.6 2.7 1 1 2 3 3 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KZN89486.1 - 1.1 9.0 8.2 1.2 8.9 3.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KZN89486.1 - 1.2 9.0 5.9 2.6 8.0 0.9 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KZN89486.1 - 1.4 8.4 11.2 11 5.5 7.8 2.3 1 1 1 2 2 2 0 IncA protein COMP PF11598.3 KZN89486.1 - 1.5 8.9 4.2 0.38 10.8 0.5 1.8 2 0 0 2 2 1 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.5 KZN89486.1 - 2.4 8.3 9.0 0.79 9.8 3.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Transposase_22 PF02994.9 KZN89486.1 - 2.5 6.4 11.9 0.0081 14.7 1.8 1.5 2 0 0 2 2 1 0 L1 transposable element Tup_N PF08581.5 KZN89486.1 - 3.6 7.8 11.8 1.9 8.7 0.1 3.1 3 0 0 3 3 3 0 Tup N-terminal BLOC1_2 PF10046.4 KZN89486.1 - 5 7.3 9.7 2.4 8.3 2.2 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sulfate_transp PF00916.15 KZN89488.1 - 7.2e-75 251.5 8.0 1.4e-74 250.5 5.5 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KZN89488.1 - 2.4e-32 110.4 3.8 2.4e-32 110.4 2.6 3.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KZN89488.1 - 5.1e-09 35.5 0.0 1.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KZN89488.1 - 0.0015 18.1 1.8 0.0015 18.1 1.2 3.7 4 0 0 4 4 4 1 Stannin transmembrane ATP-synt_C PF00137.16 KZN89489.1 - 1.2e-14 53.8 10.6 2.2e-14 53.0 7.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF1349 PF07081.6 KZN89490.1 - 1.9e-19 69.6 0.0 1.4e-18 66.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) DUF2651 PF10852.3 KZN89491.1 - 0.014 15.7 2.0 0.014 15.7 1.4 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2651) Cript PF10235.4 KZN89492.1 - 1.8e-34 117.9 7.2 1.8e-34 117.9 5.0 1.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.2 KZN89492.1 - 0.009 15.8 15.0 0.052 13.3 6.5 2.6 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KZN89492.1 - 0.082 12.1 11.0 1.4 8.2 2.1 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KZN89492.1 - 0.17 11.3 12.7 15 5.2 0.1 3.3 2 1 0 2 2 2 0 zinc-ribbon domain AAA_29 PF13555.1 KZN89492.1 - 0.63 9.6 2.3 36 3.9 0.0 2.5 2 1 0 2 2 2 0 P-loop containing region of AAA domain zf-BED PF02892.10 KZN89492.1 - 1.1 9.1 5.4 9.5 6.0 1.2 2.5 2 0 0 2 2 2 0 BED zinc finger DUF581 PF04570.9 KZN89492.1 - 5.4 6.3 13.0 4 6.7 1.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) NinF PF05810.7 KZN89492.1 - 7.9 6.3 9.1 11 5.8 0.0 2.8 2 1 1 3 3 3 0 NinF protein Prim_Zn_Ribbon PF08273.7 KZN89492.1 - 8.6 6.5 11.1 31 4.7 0.0 3.9 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2039 PF10217.4 KZN89492.1 - 9.2 6.3 19.2 4.9 7.2 8.5 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) MRP-L46 PF11788.3 KZN89493.1 - 2e-35 121.8 1.1 4.1e-35 120.7 0.8 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KZN89493.1 - 0.0066 16.0 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 KZN89494.1 - 7.7e-45 153.2 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease HDA2-3 PF11496.3 KZN89494.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF572 PF04502.8 KZN89495.1 - 0.0094 15.2 10.4 0.015 14.5 7.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4137 PF13593.1 KZN89496.1 - 3.1e-90 302.4 16.7 3.5e-90 302.2 11.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 KZN89496.1 - 1.6e-08 34.2 4.5 1.6e-08 34.2 3.1 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family LrgA PF03788.9 KZN89496.1 - 6.2 6.6 11.7 0.067 12.9 1.2 2.8 2 1 0 2 2 2 0 LrgA family Mito_carr PF00153.22 KZN89497.1 - 2e-67 222.9 4.4 2e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 KZN89498.1 - 4.5e-15 55.6 0.0 6.3e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pinin_SDK_memA PF04696.8 KZN89499.1 - 1.3e-27 95.9 10.7 1.3e-27 95.9 7.4 2.3 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 KZN89500.1 - 4.5e-52 174.6 9.3 5.1e-52 174.4 6.4 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KZN89500.1 - 0.9 9.4 15.4 8.3 6.3 1.6 2.7 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 KZN89500.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 KZN89500.1 - 4.6 4.7 5.8 4.7 4.7 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KZN89500.1 - 8.5 6.1 15.7 0.22 11.2 4.6 2.5 1 1 1 2 2 2 0 PHD-finger Abhydrolase_6 PF12697.2 KZN89501.1 - 5.1e-31 108.3 0.2 1.3e-29 103.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN89501.1 - 2e-14 53.7 0.1 1.6e-08 34.3 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89501.1 - 3.9e-09 36.3 0.0 1.2e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN89501.1 - 0.00037 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KZN89501.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Saccharop_dh PF03435.13 KZN89502.1 - 1.5e-21 76.8 0.0 3e-21 75.8 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN89502.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.14 KZN89503.1 - 9e-41 137.6 10.0 9.9e-41 137.5 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KZN89503.1 - 0.0012 18.2 3.2 0.12 11.8 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KZN89503.1 - 0.0026 17.5 1.9 0.0039 16.9 1.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 KZN89503.1 - 0.049 13.3 4.1 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger GCC2_GCC3 PF07699.8 KZN89503.1 - 0.08 12.5 0.4 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 zf-H2C2_2 PF13465.1 KZN89503.1 - 0.23 11.8 4.8 3.1 8.2 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Tnp_zf-ribbon_2 PF13842.1 KZN89503.1 - 0.25 11.7 2.2 0.61 10.5 1.5 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.21 KZN89503.1 - 0.3 11.4 3.4 7.8 7.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type NOB1_Zn_bind PF08772.6 KZN89503.1 - 0.32 10.8 3.1 0.56 10.0 0.8 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rep_fac-A_C PF08646.5 KZN89503.1 - 0.51 10.0 2.8 0.88 9.2 2.0 1.4 1 1 0 1 1 1 0 Replication factor-A C terminal domain PHD PF00628.24 KZN89504.1 - 1.1e-10 41.0 13.4 1.1e-10 40.9 3.4 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KZN89504.1 - 6.5e-10 38.6 2.9 6.5e-10 38.6 2.0 3.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KZN89504.1 - 4.9e-07 29.3 0.5 4.9e-07 29.3 0.3 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 KZN89504.1 - 1.7e-06 28.0 0.3 1.7e-06 28.0 0.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN89504.1 - 1.9e-06 27.7 0.6 1.9e-06 27.7 0.4 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN89504.1 - 3.5e-06 26.5 0.6 3.5e-06 26.5 0.4 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN89504.1 - 3.7e-06 26.4 3.2 3.7e-06 26.4 2.2 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 KZN89504.1 - 0.0005 19.3 1.9 0.0005 19.3 1.3 1.8 2 0 0 2 2 1 1 PHD-finger Prok-RING_4 PF14447.1 KZN89504.1 - 0.00055 19.4 3.9 0.0021 17.5 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KZN89504.1 - 0.00057 19.6 0.2 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 KZN89504.1 - 0.026 13.7 0.0 0.026 13.7 0.0 2.6 4 0 0 4 4 4 0 Rtf2 RING-finger zf-C2HC_2 PF13913.1 KZN89504.1 - 0.048 13.3 3.5 0.18 11.5 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_4 PF14570.1 KZN89504.1 - 1.6 8.3 5.0 0.35 10.4 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KZN89504.1 - 1.9 8.2 9.7 0.12 12.0 1.1 3.0 3 1 0 3 3 3 0 RING-type zinc-finger DZR PF12773.2 KZN89504.1 - 1.9 8.3 9.2 1.3e+02 2.5 3.5 3.2 1 1 1 2 2 2 0 Double zinc ribbon Pyr_redox_3 PF13738.1 KZN89505.1 - 3.8e-29 102.2 0.0 5.5e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN89505.1 - 8.7e-18 63.8 0.0 3.5e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN89505.1 - 7.8e-13 48.0 0.1 2.2e-09 36.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN89505.1 - 1.3e-10 41.1 0.0 6.9e-09 35.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89505.1 - 4.7e-06 26.6 0.0 0.00013 21.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN89505.1 - 5.2e-05 22.4 0.0 0.0059 15.7 0.0 2.7 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.1 KZN89505.1 - 0.00018 21.3 1.1 0.036 13.8 0.4 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KZN89505.1 - 0.00044 19.2 3.7 0.016 14.1 0.2 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN89505.1 - 0.00093 18.1 0.0 0.0019 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN89505.1 - 0.0031 17.8 0.3 2.2 8.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN89505.1 - 0.016 13.6 0.6 0.15 10.5 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KZN89505.1 - 0.05 13.7 0.0 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KZN89505.1 - 0.082 13.1 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KZN89505.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KZN89505.1 - 0.33 9.9 3.1 0.17 10.9 0.3 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KZN89506.1 - 6.9e-20 71.0 0.2 1.1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1924 PF09086.6 KZN89506.1 - 0.074 13.1 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) ADH_zinc_N PF00107.21 KZN89507.1 - 4.4e-17 61.8 0.1 7.2e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN89507.1 - 4.8e-10 39.1 0.1 2e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN89507.1 - 6.1e-06 27.1 0.0 1.3e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KZN89507.1 - 0.036 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.1 KZN89508.1 - 1.5e-28 100.1 0.0 1.8e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN89508.1 - 2.4e-19 69.8 0.7 3.1e-19 69.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase UPF0146 PF03686.8 KZN89508.1 - 0.14 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Abhydrolase_3 PF07859.8 KZN89509.1 - 6.5e-44 150.0 0.0 8.9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN89509.1 - 6.3e-10 38.3 4.2 1.2e-09 37.4 1.6 2.1 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KZN89509.1 - 0.00022 21.2 0.2 0.00041 20.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89509.1 - 0.0034 17.1 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN89509.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KZN89509.1 - 0.043 13.0 0.0 9.6 5.3 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family EnY2 PF10163.4 KZN89510.1 - 0.00052 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 RA PF00788.18 KZN89511.1 - 2.3e-16 60.0 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 KZN89511.1 - 1.2e-14 53.8 0.0 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KZN89511.1 - 2.7e-13 49.8 0.0 4.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.1 KZN89511.1 - 0.12 12.2 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Ras-binding domain of Byr2 Fungal_trans PF04082.13 KZN89512.1 - 6e-23 81.0 1.4 8.2e-23 80.6 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.7 KZN89513.1 - 6.8e-31 106.2 0.6 1.2e-30 105.5 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN89513.1 - 1e-22 80.0 0.3 1.6e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN89513.1 - 0.00045 21.1 0.0 0.00087 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KZN89513.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KZN89513.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN89513.1 - 0.049 13.1 0.2 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.19 KZN89514.1 - 7.3e-93 311.5 27.5 8.5e-93 311.3 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89514.1 - 4e-37 127.7 43.9 1.1e-31 109.9 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN89514.1 - 0.0024 17.6 1.8 0.59 9.9 0.1 3.2 2 1 1 3 3 3 2 MFS_1 like family DUF3317 PF11779.3 KZN89514.1 - 0.48 9.8 5.3 2.3 7.7 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DUF2530 PF10745.4 KZN89514.1 - 7.5 6.6 8.8 1.5 8.8 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Polysacc_deac_1 PF01522.16 KZN89516.1 - 2.2e-31 108.0 0.0 4.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KZN89516.1 - 0.0067 16.3 15.3 0.0067 16.3 10.6 3.0 2 1 1 3 3 3 1 Chitin recognition protein Conotoxin PF02950.12 KZN89516.1 - 4.6 8.1 12.6 0.98 10.2 0.4 2.8 2 0 0 2 2 2 0 Conotoxin HEAT_2 PF13646.1 KZN89517.1 - 2.9e-05 24.2 0.9 0.00012 22.3 0.1 2.3 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KZN89517.1 - 0.00054 19.8 2.1 0.068 13.2 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat Cnd3 PF12719.2 KZN89517.1 - 0.0018 17.3 0.2 0.0045 16.0 0.0 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 KZN89517.1 - 0.0038 15.6 0.4 0.33 9.2 0.1 2.7 2 1 1 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KZN89517.1 - 0.0058 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region UME PF08064.8 KZN89517.1 - 0.0058 16.5 0.4 1.2 9.1 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain DUF4072 PF13284.1 KZN89517.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) V-ATPase_H_N PF03224.9 KZN89517.1 - 0.046 12.8 0.7 0.059 12.4 0.5 1.4 1 1 0 1 1 1 0 V-ATPase subunit H PRRSV_Env PF02340.10 KZN89517.1 - 0.081 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 PRRSV putative envelope protein DRIM PF07539.7 KZN89517.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Down-regulated in metastasis Cas_Cas02710 PF09670.5 KZN89517.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) HEAT_EZ PF13513.1 KZN89517.1 - 1.1 9.8 5.1 7.4 7.1 0.0 4.2 4 2 2 6 6 6 0 HEAT-like repeat CT47 PF15623.1 KZN89518.1 - 0.011 15.5 35.0 0.014 15.1 24.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 CENP-T PF15511.1 KZN89518.1 - 0.22 10.7 24.4 0.25 10.5 16.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1183 PF06682.7 KZN89518.1 - 3.2 7.2 5.6 0.33 10.4 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) PEP_mutase PF13714.1 KZN89519.1 - 1.2e-53 181.8 0.8 1.5e-53 181.4 0.6 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KZN89519.1 - 9.2e-14 50.5 0.3 1.3e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KZN89519.1 - 0.00011 21.4 0.1 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.11 KZN89520.1 - 4.3e-30 104.6 22.2 4.3e-30 104.6 15.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.11 KZN89522.1 - 1.7e-35 122.4 19.4 1.7e-35 122.4 13.4 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KZN89522.1 - 4.7e-23 80.4 0.0 4.7e-23 80.4 0.0 2.1 3 0 0 3 3 3 1 TRAM1-like protein Chordopox_G3 PF06129.7 KZN89522.1 - 0.068 13.3 0.5 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Sugar_tr PF00083.19 KZN89523.1 - 7.8e-108 360.9 23.0 9.6e-108 360.6 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89523.1 - 5.3e-27 94.4 32.3 5.5e-26 91.1 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN89523.1 - 2.1e-05 23.1 27.6 0.00054 18.4 4.3 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KZN89523.1 - 3e-05 22.4 0.5 6.9e-05 21.2 0.4 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KZN89523.1 - 5.4e-05 22.0 0.3 0.00011 21.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KZN89523.1 - 0.011 15.4 1.6 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 MFS_1 like family Sulfatase PF00884.18 KZN89524.1 - 8e-25 87.6 0.7 1.5e-24 86.7 0.5 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN89524.1 - 4e-07 29.6 0.3 7.6e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN89524.1 - 0.11 10.8 0.1 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Transglut_core PF01841.14 KZN89526.1 - 5.9e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KZN89526.1 - 0.0016 17.6 0.0 0.0037 16.5 0.0 1.5 2 0 0 2 2 2 1 Transglutaminase-like domain Ras PF00071.17 KZN89527.1 - 3.3e-31 107.8 0.2 4.4e-31 107.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN89527.1 - 3e-20 72.8 0.1 1.1e-19 71.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KZN89527.1 - 1.1e-06 27.9 0.1 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN89527.1 - 5.3e-05 22.4 0.2 7.5e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KZN89527.1 - 0.01 14.5 6.2 0.28 9.8 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit RNR_inhib PF08591.5 KZN89527.1 - 5.9 7.8 9.2 1.1 10.2 3.6 1.8 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor WD40 PF00400.27 KZN89528.1 - 8.9e-26 88.7 7.4 3.3e-09 36.2 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KZN89528.1 - 2.9e-21 75.1 0.0 8.3e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Fungal_trans PF04082.13 KZN89529.1 - 3.1e-24 85.2 2.6 5.8e-24 84.3 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN89529.1 - 6.2e-10 38.8 12.7 0.00015 21.8 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN89529.1 - 8.6e-07 28.9 18.4 1.2e-06 28.4 4.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN89529.1 - 0.00025 21.1 17.3 0.023 15.0 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN89529.1 - 0.16 12.1 3.2 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN89529.1 - 3.1 7.8 6.7 2.6 8.0 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Clathrin PF00637.15 KZN89531.1 - 5.1e-24 84.5 1.6 3.6e-21 75.2 1.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KZN89531.1 - 1.3e-18 66.5 0.0 2.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 KZN89531.1 - 2e-05 24.8 0.1 0.096 13.3 0.0 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 KZN89531.1 - 0.00053 19.6 5.8 0.0011 18.6 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KZN89531.1 - 0.0018 18.2 5.2 0.0035 17.3 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN89531.1 - 0.0021 17.8 6.4 0.004 16.9 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 KZN89531.1 - 0.0038 16.8 0.6 0.018 14.6 0.1 2.4 2 0 0 2 2 2 1 TPR repeat DUF2334 PF10096.4 KZN89531.1 - 0.0081 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) TPR_12 PF13424.1 KZN89531.1 - 0.017 15.0 0.4 0.017 15.0 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 KZN89531.1 - 0.021 14.9 4.3 0.04 14.0 3.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN89531.1 - 0.023 14.3 5.3 0.044 13.4 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.1 KZN89531.1 - 0.032 14.8 0.6 0.35 11.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KZN89531.1 - 0.08 12.6 4.6 0.15 11.7 3.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Katanin_con80 PF13925.1 KZN89531.1 - 0.088 12.5 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 con80 domain of Katanin zf-RING_6 PF14835.1 KZN89531.1 - 0.12 12.1 1.2 0.25 11.1 0.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KZN89531.1 - 0.24 11.2 1.9 0.56 10.0 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 KZN89531.1 - 0.72 9.9 6.0 0.16 11.9 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN89531.1 - 1.8 8.5 6.0 0.45 10.4 0.2 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN89531.1 - 4.6 7.2 6.2 6 6.9 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Nha1_C PF08619.5 KZN89532.1 - 5.5e-92 309.3 46.9 5.5e-92 309.3 32.5 2.5 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KZN89532.1 - 1e-67 228.3 15.2 1.3e-67 227.9 10.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Serglycin PF04360.7 KZN89532.1 - 0.0038 16.9 6.2 0.0087 15.7 4.3 1.5 1 0 0 1 1 1 1 Serglycin PX PF00787.19 KZN89533.1 - 7.4e-17 61.1 0.2 1.8e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 KZN89533.1 - 0.0083 14.7 0.5 0.013 14.1 0.3 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.1 KZN89533.1 - 0.023 14.4 0.7 0.023 14.4 0.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit Aldedh PF00171.17 KZN89534.1 - 5.7e-104 348.0 0.0 6.7e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.13 KZN89535.1 - 2.5e-36 125.2 0.0 3.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase ATG2_CAD PF13329.1 KZN89536.1 - 0.077 12.5 0.4 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3530 PF12048.3 KZN89536.1 - 0.13 11.1 0.3 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Rota_NS6 PF04866.7 KZN89536.1 - 0.22 11.5 2.1 0.29 11.1 0.0 2.2 3 0 0 3 3 3 0 Rotavirus non-structural protein 6 Flavin_Reduct PF01613.13 KZN89538.1 - 2.2e-16 60.0 0.0 3.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Pyridox_oxidase PF01243.15 KZN89538.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF347 PF03988.7 KZN89539.1 - 0.048 13.5 0.1 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) TMEM154 PF15102.1 KZN89539.1 - 0.051 13.2 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Claudin_2 PF13903.1 KZN89539.1 - 0.052 13.2 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 KZN89539.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 KZN89539.1 - 0.15 11.7 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Syndecan domain AAA PF00004.24 KZN89540.1 - 2.5e-07 30.9 0.1 1.3e-06 28.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN89540.1 - 7.8e-05 22.7 0.1 0.00053 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN89540.1 - 0.00051 20.2 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN89540.1 - 0.00053 20.8 0.0 0.0022 18.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KZN89540.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KZN89540.1 - 0.0094 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KZN89540.1 - 0.014 14.4 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 KZN89540.1 - 0.016 13.9 0.1 0.14 10.7 0.0 2.6 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KZN89540.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KZN89540.1 - 0.036 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 KZN89540.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 LRR_4 PF12799.2 KZN89542.1 - 1.6e-28 97.7 29.5 2.8e-06 26.8 0.1 9.3 3 1 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN89542.1 - 1.1e-23 82.6 32.5 6.5e-07 29.0 0.4 7.9 4 2 4 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 KZN89542.1 - 1.1e-10 39.9 29.1 0.64 10.2 0.0 12.1 11 2 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.1 KZN89542.1 - 4.7e-10 38.4 24.6 0.25 11.5 0.0 11.0 8 2 2 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 KZN89542.1 - 1.3e-08 33.6 32.0 1 9.8 0.2 11.7 13 0 0 13 13 13 4 Leucine rich repeat LRR_9 PF14580.1 KZN89542.1 - 2.8e-06 27.0 10.7 0.01 15.4 0.6 3.9 1 1 3 4 4 4 3 Leucine-rich repeat Cupin_2 PF07883.6 KZN89543.1 - 0.0011 18.3 0.0 0.021 14.2 0.0 2.5 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.17 KZN89543.1 - 0.0067 15.8 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 KZN89543.1 - 0.0082 15.4 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein MFS_1 PF07690.11 KZN89544.1 - 8.8e-29 100.3 33.9 2.5e-24 85.6 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SecE PF00584.15 KZN89544.1 - 0.01 15.3 1.2 3.3 7.3 0.0 3.2 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Phage_holin_5 PF06946.6 KZN89544.1 - 0.049 13.7 2.6 0.35 11.0 0.1 2.7 2 0 0 2 2 2 0 Phage holin NfeD PF01957.13 KZN89544.1 - 9.4 6.3 10.0 2.7 8.1 0.3 3.5 3 2 0 3 3 3 0 NfeD-like C-terminal, partner-binding DAO PF01266.19 KZN89545.1 - 1.8e-55 188.2 0.2 2.2e-55 188.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN89545.1 - 0.00039 20.5 0.0 0.025 14.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89545.1 - 0.00047 20.1 0.4 0.0013 18.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN89545.1 - 0.048 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 KZN89547.1 - 2.8e-18 66.0 0.0 9.7e-15 54.4 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89547.1 - 5.3e-08 32.2 0.0 1.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Sulfatase PF00884.18 KZN89548.1 - 2.2e-18 66.4 1.0 2.4e-18 66.3 0.1 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KZN89548.1 - 9e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN89548.1 - 0.00028 19.4 0.0 0.00041 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KZN89548.1 - 0.089 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 KZN89548.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Mg_chelatase PF01078.16 KZN89548.1 - 0.16 11.1 0.1 0.59 9.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Methyltransf_23 PF13489.1 KZN89549.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TIP120 PF08623.5 KZN89550.1 - 7e-62 207.9 0.2 6.9e-61 204.7 0.0 2.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KZN89550.1 - 2.1e-08 33.5 9.5 0.1 12.7 0.0 8.8 9 0 0 9 9 9 2 HEAT repeat Arm PF00514.18 KZN89550.1 - 0.023 14.5 1.3 2.5 8.0 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 KZN89550.1 - 0.06 13.4 0.0 3.8 7.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 KZN89550.1 - 0.76 10.4 5.1 2 9.1 0.3 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KZN89550.1 - 1.4 9.5 27.6 1.2 9.6 0.0 9.1 9 3 4 13 13 13 0 HEAT-like repeat DBR1 PF05011.8 KZN89551.1 - 2e-41 141.2 0.0 5.4e-41 139.8 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KZN89551.1 - 8.8e-09 35.0 1.3 1.7e-08 34.0 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 KZN89552.1 - 8.6e-25 86.4 0.3 5.5e-24 83.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KZN89552.1 - 3.7e-06 26.3 0.0 1.1e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) zf-ZPR1 PF03367.8 KZN89553.1 - 9.6e-93 307.6 0.0 1.5e-46 157.5 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrome_C554 PF13435.1 KZN89553.1 - 0.012 15.7 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c554 and c-prime HypA PF01155.14 KZN89553.1 - 0.019 14.6 1.1 0.79 9.4 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FeS PF04060.8 KZN89553.1 - 0.025 14.1 0.9 0.06 12.9 0.6 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster DUF3716 PF12511.3 KZN89553.1 - 0.1 12.2 1.9 5.3 6.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) Elf1 PF05129.8 KZN89553.1 - 0.26 10.9 1.6 11 5.7 0.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Cytochrome_C7 PF14522.1 KZN89553.1 - 0.37 10.4 4.4 0.93 9.1 1.0 2.7 2 1 0 2 2 2 0 Cytochrome c7 Acyl_transf_3 PF01757.17 KZN89554.1 - 1.4e-23 83.2 21.1 7.5e-23 80.8 14.7 2.1 1 1 0 1 1 1 1 Acyltransferase family ABC_tran PF00005.22 KZN89555.1 - 6.8e-33 113.8 0.0 1.3e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KZN89555.1 - 7.7e-28 97.6 12.5 1e-27 97.2 8.2 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KZN89555.1 - 1.5e-07 30.9 0.0 1.1e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN89555.1 - 3.9e-05 23.7 0.0 0.021 14.8 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN89555.1 - 0.0012 18.2 0.1 0.003 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KZN89555.1 - 0.0017 18.1 0.2 0.021 14.7 0.2 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KZN89555.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KZN89555.1 - 0.042 13.0 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KZN89555.1 - 0.099 12.3 0.1 0.92 9.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KZN89555.1 - 0.12 11.7 0.1 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain APH PF01636.18 KZN89556.1 - 1.2e-16 61.1 0.7 8.3e-10 38.8 0.0 3.0 2 1 0 2 2 2 2 Phosphotransferase enzyme family Glycos_transf_1 PF00534.15 KZN89556.1 - 3.1e-12 46.2 0.0 6.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KZN89556.1 - 2.3e-07 31.0 0.0 8.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Choline_kinase PF01633.15 KZN89556.1 - 3.2e-05 23.5 0.0 0.0093 15.5 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.6 KZN89556.1 - 0.0035 16.6 0.0 0.0089 15.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 KZN89556.1 - 0.019 14.1 0.0 0.73 8.9 0.0 2.4 2 0 0 2 2 2 0 Ecdysteroid kinase Pro_isomerase PF00160.16 KZN89557.1 - 4.4e-37 127.6 0.0 5.4e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC6 PF05460.8 KZN89558.1 - 4.6e-93 312.1 0.0 5.3e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF2419 PF10343.4 KZN89559.1 - 1e-142 474.5 0.0 1.3e-142 474.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 KZN89559.1 - 0.072 12.9 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.16 KZN89560.1 - 1.8e-40 137.8 0.9 3e-40 137.1 0.1 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 KZN89560.1 - 4.3e-28 96.6 0.4 8.9e-28 95.6 0.3 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KZN89560.1 - 1.1e-19 70.3 0.1 2.9e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KZN89560.1 - 1.7e-18 65.7 1.3 1.7e-18 65.7 0.9 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KZN89560.1 - 0.00027 21.0 0.1 0.0027 17.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KZN89560.1 - 0.0022 18.1 0.0 0.0078 16.4 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KZN89560.1 - 0.11 12.9 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sec20 PF03908.8 KZN89560.1 - 0.15 11.8 0.7 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Sec20 adh_short PF00106.20 KZN89561.1 - 1e-26 93.8 0.8 3.1e-24 85.7 0.6 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89561.1 - 1.5e-12 47.7 0.1 2.9e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89561.1 - 8.6e-12 45.0 0.9 1e-10 41.5 0.6 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89561.1 - 2e-07 30.7 0.6 0.0001 21.8 0.4 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN89561.1 - 1.1e-05 24.5 0.1 0.00034 19.5 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KZN89561.1 - 9.6e-05 22.5 0.5 0.0014 18.6 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KZN89561.1 - 0.00051 20.4 0.2 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KZN89561.1 - 0.0025 17.8 1.7 0.16 11.9 0.3 2.2 1 1 1 2 2 2 2 NADH(P)-binding NAD_binding_4 PF07993.7 KZN89561.1 - 0.012 14.5 0.1 0.021 13.7 0.1 1.5 1 0 0 1 1 1 0 Male sterility protein DFP PF04127.10 KZN89561.1 - 0.043 13.4 0.3 1.1 8.8 0.1 2.7 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein Skp1_POZ PF03931.10 KZN89562.1 - 4e-07 30.0 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.1 KZN89563.1 - 4.1e-08 32.7 12.3 7.3e-08 31.9 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Malic_M PF03949.10 KZN89564.1 - 2e-81 273.3 0.0 2.7e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KZN89564.1 - 2.1e-65 219.7 0.4 3.2e-65 219.1 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Gag_p24 PF00607.15 KZN89564.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Na_Ca_ex PF01699.19 KZN89565.1 - 6e-10 38.8 26.5 9.3e-08 31.7 6.3 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein NACHT PF05729.7 KZN89566.1 - 8e-09 35.3 0.0 3.4e-08 33.3 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KZN89566.1 - 3.4e-06 27.2 0.0 4e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN89566.1 - 0.00063 19.7 1.6 0.016 15.2 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KZN89566.1 - 0.0024 16.9 0.1 0.29 10.1 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.1 KZN89566.1 - 0.003 18.3 0.0 0.033 14.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KZN89566.1 - 0.01 16.1 0.0 0.081 13.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KZN89566.1 - 0.04 13.7 0.2 16 5.3 0.0 3.7 4 1 0 4 4 4 0 AAA domain KAP_NTPase PF07693.9 KZN89566.1 - 0.056 12.4 0.3 5.9 5.7 0.1 2.5 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 KZN89566.1 - 0.057 13.7 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 KZN89566.1 - 0.058 12.8 0.3 0.77 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 KZN89566.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KZN89566.1 - 0.094 12.9 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 KZN89566.1 - 0.12 12.2 0.0 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat CFEM PF05730.6 KZN89568.1 - 1.6e-15 56.6 10.8 2.9e-15 55.8 7.5 1.5 1 0 0 1 1 1 1 CFEM domain CytochromB561_N PF09786.4 KZN89568.1 - 1.2 7.5 5.9 1.4 7.2 4.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal PAP1 PF08601.5 KZN89568.1 - 9 5.8 14.4 11 5.6 10.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DNA_pol_delta_4 PF04081.8 KZN89569.1 - 1.5e-24 86.6 0.6 2.2e-24 86.0 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Mei5 PF10376.4 KZN89569.1 - 6.8 6.1 6.1 5.7 6.3 1.7 2.2 2 1 0 2 2 2 0 Double-strand recombination repair protein Arrestin_C PF02752.17 KZN89570.1 - 7.1e-16 58.5 0.0 4e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.11 KZN89571.1 - 2.8e-42 144.7 18.1 2.8e-42 144.7 12.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN89571.1 - 4.3e-12 45.3 17.4 4.2e-11 42.1 12.1 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KZN89571.1 - 0.00026 19.1 3.3 0.073 11.1 0.2 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KZN89571.1 - 0.0018 16.4 0.7 0.0018 16.4 0.5 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.8 KZN89571.1 - 0.0055 14.9 2.4 0.0078 14.4 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_kinase PF02595.10 KZN89572.1 - 7.6e-108 360.5 4.9 8.5e-108 360.4 3.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family NAD_binding_10 PF13460.1 KZN89572.1 - 0.072 13.0 0.0 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding Melibiase PF02065.13 KZN89574.1 - 7.3e-160 531.9 0.0 8.9e-160 531.6 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KZN89574.1 - 2.7e-07 29.7 0.0 4.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 tRNA_int_end_N2 PF12928.2 KZN89576.1 - 1.6e-34 117.1 0.0 2.5e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KZN89576.1 - 0.0037 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain ThiF PF00899.16 KZN89577.1 - 1.7e-08 34.3 0.0 5.3e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 ThiF family Rib_5-P_isom_A PF06026.9 KZN89578.1 - 4e-38 130.4 0.0 2.5e-36 124.5 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KZN89578.1 - 0.016 14.8 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain DND1_DSRM PF14709.1 KZN89578.1 - 0.025 14.8 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 WD40 PF00400.27 KZN89579.1 - 2.5e-23 81.0 2.0 0.00012 21.7 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat SGL PF08450.7 KZN89579.1 - 0.047 13.0 0.0 0.29 10.4 0.0 2.1 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region ATP_bind_1 PF03029.12 KZN89580.1 - 4.1e-76 255.6 0.0 5.2e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KZN89580.1 - 0.00033 21.4 4.4 0.00069 20.4 1.8 2.6 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KZN89580.1 - 0.00071 19.1 0.1 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 KZN89580.1 - 0.00072 18.4 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 KZN89580.1 - 0.0039 17.1 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KZN89580.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KZN89580.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KZN89580.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 KZN89580.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KZN89580.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KZN89580.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Fer4_NifH PF00142.13 KZN89580.1 - 0.22 10.6 0.6 1.1 8.4 0.1 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNase_P_Rpp14 PF01900.14 KZN89581.1 - 4.4e-35 119.8 0.0 5.8e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 KZN89582.1 - 1.4e-18 66.7 0.0 5.5e-16 58.2 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KZN89582.1 - 2e-18 66.6 0.0 8.2e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KZN89582.1 - 9.5e-15 54.5 0.1 1.7e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KZN89582.1 - 4.2e-06 26.3 0.0 8.5e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CEP1-DNA_bind PF09287.5 KZN89582.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding ATP-grasp_2 PF08442.5 KZN89583.1 - 9e-09 35.0 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain MBOAT_2 PF13813.1 KZN89584.1 - 1.3e-22 79.6 1.1 1.3e-22 79.6 0.8 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PhyH PF05721.8 KZN89585.1 - 0.11 12.5 0.2 0.51 10.3 0.1 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Allexi_40kDa PF05549.6 KZN89586.1 - 0.0017 17.6 3.3 0.0025 17.1 2.3 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Spc24 PF08286.6 KZN89586.1 - 0.077 12.6 5.7 0.12 12.0 4.0 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Nup88 PF10168.4 KZN89586.1 - 0.078 10.8 5.9 0.1 10.4 4.1 1.0 1 0 0 1 1 1 0 Nuclear pore component TMV_coat PF00721.16 KZN89586.1 - 0.1 12.4 2.1 0.53 10.1 0.1 2.3 1 1 1 2 2 2 0 Virus coat protein (TMV like) AAA_27 PF13514.1 KZN89586.1 - 0.12 10.0 6.2 0.15 9.7 4.3 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 KZN89586.1 - 0.12 10.9 8.3 0.16 10.5 5.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KZN89586.1 - 0.13 12.3 8.6 0.19 11.8 5.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KZN89586.1 - 0.17 11.4 5.0 0.24 10.9 3.5 1.2 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 KZN89586.1 - 0.28 10.3 6.4 0.39 9.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF342 PF03961.8 KZN89586.1 - 0.88 7.9 7.9 1.1 7.5 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 KZN89586.1 - 1.1 9.1 10.9 1.6 8.6 7.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.7 KZN89586.1 - 1.3 8.7 9.2 2.1 8.1 6.4 1.3 1 0 0 1 1 1 0 Laminin Domain II SlyX PF04102.7 KZN89586.1 - 6.7 7.1 9.4 42 4.6 4.6 2.8 1 1 1 2 2 2 0 SlyX XAP5 PF04921.9 KZN89587.1 - 7.5e-81 271.2 0.3 1.3e-80 270.4 0.0 1.4 2 0 0 2 2 2 1 XAP5, circadian clock regulator Mcm10 PF09332.6 KZN89587.1 - 2.5 7.3 5.2 4.5 6.5 3.6 1.4 1 0 0 1 1 1 0 Mcm10 replication factor Fip1 PF05182.8 KZN89588.1 - 2.1e-20 71.6 1.1 3.6e-20 70.9 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif Ribosomal_60s PF00428.14 KZN89588.1 - 3 8.2 17.4 0.16 12.3 0.7 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Cpn10 PF00166.16 KZN89589.1 - 4.7e-27 93.7 0.0 5.3e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TauD PF02668.11 KZN89591.1 - 7.2e-47 160.2 0.1 8.9e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleoporin_FG PF13634.1 KZN89592.1 - 1.1e-09 38.4 102.9 3.5e-07 30.4 26.8 3.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF1664 PF07889.7 KZN89592.1 - 0.13 12.0 0.5 0.69 9.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 KZN89592.1 - 0.3 11.0 1.4 42 4.1 0.0 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 KZN89593.1 - 9.7e-08 31.6 6.8 0.24 11.3 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Lactonase PF10282.4 KZN89593.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.1 KZN89594.1 - 5.4e-12 46.2 0.0 9.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN89594.1 - 2.9e-05 24.5 0.0 0.0002 21.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN89594.1 - 7.2e-05 22.4 0.0 0.00059 19.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like NIR_SIR PF01077.17 KZN89594.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain TPR_11 PF13414.1 KZN89595.1 - 1.6e-13 50.1 0.4 8.4e-13 47.7 0.1 2.1 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KZN89595.1 - 5.2e-07 28.9 1.3 0.005 16.3 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN89595.1 - 1.2e-06 28.4 1.0 2.3e-06 27.4 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89595.1 - 8.8e-06 25.2 0.8 0.053 13.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN89595.1 - 0.0011 18.6 1.7 2 8.4 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89595.1 - 0.0012 19.4 0.5 0.043 14.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN89595.1 - 0.0016 18.5 0.3 0.0033 17.5 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KZN89595.1 - 0.015 15.6 0.2 0.52 10.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN89595.1 - 0.083 13.5 1.0 1.5 9.6 0.0 3.4 4 1 1 5 5 5 0 Tetratricopeptide repeat GBP_C PF02841.9 KZN89595.1 - 7.8 5.5 8.7 1.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain dUTPase PF00692.14 KZN89598.1 - 9e-11 41.3 0.0 1.6e-10 40.5 0.0 1.4 2 0 0 2 2 2 1 dUTPase AMP-binding PF00501.23 KZN89599.1 - 3.6e-84 282.5 0.0 4.1e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN89599.1 - 5.3e-11 43.3 0.0 1.3e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KZN89600.1 - 2.4e-52 177.8 32.8 1.1e-46 159.2 12.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KZN89600.1 - 8.7e-07 27.4 9.1 8.7e-07 27.4 6.3 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Mem_trans PF03547.13 KZN89600.1 - 0.056 11.7 1.6 0.091 11.0 0.0 2.0 2 0 0 2 2 2 0 Membrane transport protein ATG22 PF11700.3 KZN89600.1 - 0.16 10.4 21.6 0.22 9.9 7.5 3.1 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like 3Beta_HSD PF01073.14 KZN89601.1 - 2.3e-12 46.2 0.0 3.4e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN89601.1 - 8.4e-12 45.0 0.0 1.7e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN89601.1 - 2.4e-11 43.9 0.0 5.3e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN89601.1 - 2e-07 30.2 0.0 4.4e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KZN89601.1 - 4e-06 26.8 1.9 2.4e-05 24.2 0.3 2.8 3 1 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.8 KZN89601.1 - 2.3e-05 23.7 0.2 5.8e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KZN89601.1 - 0.00054 19.6 0.2 0.0048 16.5 0.1 2.2 1 1 0 1 1 1 1 KR domain DUF3112 PF11309.3 KZN89602.1 - 1.1e-45 155.3 16.5 7.9e-43 146.0 2.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.23 KZN89603.1 - 9.4e-44 149.2 0.7 1.2e-43 148.8 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 KZN89604.1 - 9.8e-34 116.1 0.0 1.2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KZN89604.1 - 1.8e-18 66.9 19.1 1.8e-18 66.9 13.2 3.7 3 1 1 4 4 4 1 PI31 proteasome regulator Acyl-CoA_dh_1 PF00441.19 KZN89605.1 - 1.3e-28 100.0 2.6 2.6e-28 98.9 1.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KZN89605.1 - 4.4e-19 68.0 0.1 1.1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KZN89605.1 - 5.8e-19 67.3 0.4 1.5e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KZN89605.1 - 1e-06 29.2 0.0 3.1e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2153 PF09921.4 KZN89605.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Acyl-CoA_dh_2 PF08028.6 KZN89605.1 - 0.023 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain UvdE PF03851.9 KZN89606.1 - 2.7e-112 374.3 0.0 3.4e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE ADH_N PF08240.7 KZN89607.1 - 0.0013 18.4 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 KZN89607.1 - 0.0038 16.9 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN89607.1 - 0.023 15.1 0.1 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Leukemia_assc_2 PF15197.1 KZN89607.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Leukemia-associated protein 2 MFS_1 PF07690.11 KZN89608.1 - 3.5e-32 111.4 77.6 9.3e-27 93.6 31.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN89608.1 - 0.057 11.8 32.9 0.0087 14.4 2.0 2.8 1 1 2 3 3 3 0 MFS/sugar transport protein DUF1517 PF07466.6 KZN89608.1 - 0.31 9.9 0.6 0.77 8.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Hexokinase_2 PF03727.11 KZN89609.1 - 5.1e-25 88.0 0.0 8.1e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KZN89609.1 - 3.6e-20 72.1 0.0 1.6e-19 70.0 0.0 1.9 1 1 0 1 1 1 1 Hexokinase TatD_DNase PF01026.16 KZN89610.1 - 1.9e-41 141.9 0.0 2.3e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF936 PF06075.7 KZN89611.1 - 0.13 11.1 12.5 0.19 10.6 8.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2413 PF10310.4 KZN89611.1 - 0.79 8.4 15.4 0.014 14.2 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Tim54 PF11711.3 KZN89611.1 - 0.82 8.1 5.3 1.2 7.7 0.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Macoilin PF09726.4 KZN89611.1 - 2.6 6.2 20.8 4 5.6 14.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 KZN89611.1 - 4.1 6.5 26.6 0.91 8.6 14.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal APH PF01636.18 KZN89613.1 - 7.1e-15 55.3 0.0 1.4e-14 54.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN89613.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.12 KZN89613.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MARVEL PF01284.18 KZN89615.1 - 0.13 12.0 15.9 0.92 9.3 11.2 1.9 1 1 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.7 KZN89615.1 - 0.25 10.8 5.6 2.4 7.6 0.2 2.2 1 1 1 2 2 2 0 SUR7/PalI family CENP-S PF15630.1 KZN89616.1 - 3.3e-35 120.1 0.0 4.2e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KZN89616.1 - 1.7e-05 24.4 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KZN89616.1 - 2.3e-05 23.8 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KZN89616.1 - 0.021 14.6 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KZN89616.1 - 0.039 14.0 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF1015 PF06245.6 KZN89616.1 - 0.078 11.4 0.0 0.095 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) TAF PF02969.12 KZN89616.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 KZN89616.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PGA2 PF07543.7 KZN89617.1 - 3.8e-33 114.2 2.7 5e-33 113.8 1.8 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 MMS1_N PF10433.4 KZN89618.1 - 3.7e-90 302.4 0.0 5.9e-90 301.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KZN89618.1 - 1.3e-76 257.7 0.1 2.1e-72 243.9 0.0 3.6 4 0 0 4 4 4 2 CPSF A subunit region Tbf5 PF06331.7 KZN89618.1 - 0.12 12.2 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 FAD_binding_1 PF00667.15 KZN89619.1 - 7.5e-60 202.0 0.0 1.2e-59 201.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KZN89619.1 - 2.3e-34 118.4 3.4 2.7e-34 118.2 1.5 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 KZN89619.1 - 3.6e-22 78.9 0.1 5e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KZN89619.1 - 0.0074 16.2 0.2 0.069 13.1 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin domain MOR2-PAG1_N PF14222.1 KZN89620.1 - 1.5e-223 743.5 0.0 2.7e-223 742.6 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KZN89620.1 - 6.7e-97 324.3 0.0 1.7e-96 322.9 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KZN89620.1 - 3.2e-34 117.7 11.4 4.4e-12 44.4 0.1 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region NAD_binding_11 PF14833.1 KZN89621.1 - 2e-32 111.7 0.0 4e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KZN89621.1 - 1.1e-31 109.8 0.2 1.8e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN89621.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KZN89621.1 - 0.0068 15.5 0.0 0.012 14.8 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KZN89621.1 - 0.033 14.1 0.1 0.43 10.5 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain TGS PF02824.16 KZN89621.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 TGS domain RRM_1 PF00076.17 KZN89622.1 - 7.4e-22 76.7 0.0 8.8e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN89622.1 - 2.9e-14 52.8 0.0 1.8e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN89622.1 - 0.00046 19.9 2.0 0.13 12.1 0.1 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VirE_N PF08800.5 KZN89622.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 VirE N-terminal domain PAPS_reduct PF01507.14 KZN89623.1 - 1.3e-24 86.9 0.0 5.1e-23 81.7 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DnaJ PF00226.26 KZN89624.1 - 2.9e-14 52.5 1.2 2.9e-14 52.5 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain HSP20 PF00011.16 KZN89624.1 - 0.02 14.7 1.8 4.9 7.0 0.9 2.7 2 1 0 2 2 2 0 Hsp20/alpha crystallin family DUF2277 PF10041.4 KZN89624.1 - 0.08 12.9 1.1 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DEAD PF00270.24 KZN89625.1 - 2.9e-44 150.5 0.0 5.5e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KZN89625.1 - 1.6e-25 88.4 0.1 3.7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KZN89625.1 - 2.1e-21 75.5 0.0 4.8e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN89625.1 - 0.0035 17.2 0.1 0.0035 17.2 0.0 2.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KZN89625.1 - 0.024 13.4 0.0 0.055 12.2 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.1 KZN89625.1 - 0.058 13.1 0.0 0.65 9.7 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain TMEM247 PF15444.1 KZN89625.1 - 0.18 11.6 5.7 0.26 11.0 2.7 2.1 2 0 0 2 2 2 0 Transmembrane protein 247 AA_permease PF00324.16 KZN89626.1 - 6.6e-125 417.1 37.8 7.5e-125 416.9 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN89626.1 - 2e-44 151.8 43.6 2.5e-44 151.5 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2576 PF10845.3 KZN89627.1 - 0.19 10.9 3.1 1.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) 7tm_2 PF00002.19 KZN89630.1 - 1.3e-10 40.7 7.2 2.1e-10 40.1 5.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KZN89630.1 - 3.7e-10 39.1 11.1 3.7e-10 39.1 7.7 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KZN89630.1 - 1.2e-07 31.0 0.2 1.6e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KZN89630.1 - 6.5e-07 29.1 12.4 1.2e-06 28.2 8.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Zn_clus PF00172.13 KZN89631.1 - 1e-06 28.5 5.0 2e-06 27.5 3.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KZN89632.1 - 3.4e-53 180.7 0.0 5.4e-33 114.4 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN89632.1 - 8.4e-35 120.1 0.0 1.4e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN89632.1 - 2.4e-05 24.2 0.1 0.00027 20.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN89632.1 - 0.0014 18.7 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN89632.1 - 0.0019 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KZN89632.1 - 0.0053 15.6 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN89632.1 - 0.026 14.4 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN89632.1 - 0.027 13.3 1.2 0.078 11.8 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KZN89632.1 - 0.042 12.3 0.1 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 KZN89632.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 KZN89633.1 - 9e-22 77.7 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN89633.1 - 2.3e-14 53.1 0.8 1.1e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN89633.1 - 1.2e-10 40.9 1.3 7.6e-09 34.9 0.7 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN89633.1 - 2.6e-07 30.1 0.0 3.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN89633.1 - 5.9e-07 28.8 0.1 9.8e-07 28.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KZN89633.1 - 7.1e-07 29.3 0.7 4e-06 26.8 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN89633.1 - 9.8e-07 27.9 0.4 1.5e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN89633.1 - 5.3e-06 26.6 0.2 8.1e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN89633.1 - 6.9e-06 25.2 0.2 0.00031 19.8 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN89633.1 - 9e-06 24.4 0.2 2.1e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KZN89633.1 - 1.3e-05 24.4 0.1 4.5e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KZN89633.1 - 1.8e-05 23.8 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KZN89633.1 - 5e-05 23.6 0.4 0.00066 20.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KZN89633.1 - 0.0079 15.8 0.2 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KZN89633.1 - 0.014 15.4 0.1 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KZN89633.1 - 0.026 14.2 0.1 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 KZN89633.1 - 0.047 13.4 0.2 0.24 11.1 0.1 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 KZN89633.1 - 0.12 12.3 0.4 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 KZN89633.1 - 0.13 11.8 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KZN89634.1 - 5.1e-07 29.1 0.1 5.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KZN89635.1 - 1.6e-26 93.6 0.0 2.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN89635.1 - 2.1e-14 52.6 0.1 9.2e-12 43.9 0.0 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN89635.1 - 7.2e-10 38.7 0.0 1.2e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN89635.1 - 1.6e-09 37.1 0.0 2.1e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KZN89635.1 - 6.3e-07 28.7 0.0 5.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.10 KZN89635.1 - 4.7e-06 25.0 0.0 0.02 13.0 0.0 2.7 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 KZN89635.1 - 4.3e-05 22.6 0.0 0.00016 20.7 0.0 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KZN89635.1 - 5.5e-05 22.2 0.0 0.00046 19.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN89635.1 - 0.00031 20.7 0.0 0.27 11.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN89635.1 - 0.00072 19.9 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89635.1 - 0.0073 16.0 1.8 0.21 11.3 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KZN89635.1 - 0.031 13.1 0.0 0.074 11.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KZN89635.1 - 0.085 12.9 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KZN89635.1 - 0.093 12.1 0.0 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 KZN89636.1 - 1.8e-27 96.3 0.3 8.3e-25 87.5 0.5 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase Rsbr_N PF08678.5 KZN89638.1 - 0.096 12.5 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Rsbr N terminal Cutinase PF01083.17 KZN89641.1 - 2.9e-51 173.7 0.8 3.4e-51 173.5 0.5 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 KZN89641.1 - 0.0012 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KZN89641.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 KZN89641.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DIM PF08194.7 KZN89641.1 - 0.58 10.1 3.6 11 6.1 2.1 2.9 2 1 0 2 2 2 0 DIM protein FA_hydroxylase PF04116.8 KZN89642.1 - 1e-15 58.1 20.2 1e-15 58.1 14.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ank PF00023.25 KZN89642.1 - 0.04 13.7 1.0 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 Ankyrin repeat Glyoxalase_2 PF12681.2 KZN89643.1 - 1.7e-10 41.4 0.0 2.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KZN89643.1 - 8.3e-06 25.8 0.0 0.0001 22.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Saccharop_dh PF03435.13 KZN89644.1 - 2.4e-22 79.4 0.1 6.8e-21 74.6 0.1 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase adh_short PF00106.20 KZN89644.1 - 0.0042 17.0 0.4 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DAO PF01266.19 KZN89645.1 - 1.8e-32 112.6 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN89645.1 - 5.9e-06 26.2 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89645.1 - 0.0022 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN89645.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KZN89645.1 - 0.018 15.4 0.1 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89645.1 - 0.023 14.4 0.1 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAT PF03417.11 KZN89646.1 - 3.3e-58 196.8 0.0 4e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KZN89646.1 - 2.5e-05 24.5 0.1 6.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase 2OG-FeII_Oxy PF03171.15 KZN89647.1 - 7.8e-21 74.2 0.0 6.9e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KZN89647.1 - 1.6e-15 57.6 0.1 2.5e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 KZN89647.1 - 0.074 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain AMP-binding PF00501.23 KZN89648.1 - 1.6e-277 919.5 0.0 1.7e-96 323.2 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KZN89648.1 - 3.2e-249 824.1 10.4 2.1e-86 289.4 0.1 4.2 4 0 0 4 4 4 4 Condensation domain Thioesterase PF00975.15 KZN89648.1 - 3.1e-45 155.1 0.0 7.6e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KZN89648.1 - 2e-42 143.2 0.1 4.9e-15 55.5 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN89648.1 - 6.5e-34 116.7 0.0 1.3e-10 42.0 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KZN89648.1 - 1.2e-25 89.5 2.1 7.9e-19 67.7 0.4 3.9 3 0 0 3 3 3 3 HxxPF-repeated domain Abhydrolase_6 PF12697.2 KZN89648.1 - 0.022 14.6 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family GH3 PF03321.8 KZN89648.1 - 0.054 12.0 2.1 0.14 10.6 0.0 2.8 4 0 0 4 4 4 0 GH3 auxin-responsive promoter Abhydrolase_5 PF12695.2 KZN89648.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KZN89648.1 - 0.076 13.1 0.1 7.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Peptidase_S41 PF03572.13 KZN89649.1 - 6.8e-10 38.6 0.0 1.5e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Methyltransf_32 PF13679.1 KZN89650.1 - 2.7e-19 69.2 0.2 5.2e-19 68.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89650.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain BNIP3 PF06553.7 KZN89652.1 - 0.079 12.3 6.2 0.096 12.0 4.3 1.1 1 0 0 1 1 1 0 BNIP3 Glyco_transf_54 PF04666.8 KZN89655.1 - 3.5e-11 42.3 0.1 4.7e-09 35.3 0.1 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF606 PF04657.8 KZN89655.1 - 0.045 13.8 0.3 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF606 PSD2 PF07624.6 KZN89656.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) FAD_binding_4 PF01565.18 KZN89657.1 - 1.7e-20 72.9 2.4 4.5e-20 71.5 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KZN89657.1 - 5.6e-09 35.7 0.6 1.3e-08 34.6 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KZN89658.1 - 0.0002 20.1 31.5 0.00078 18.2 21.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily EBP PF05241.7 KZN89659.1 - 2.5e-46 157.1 13.5 1.5e-43 148.1 5.1 2.0 1 1 1 2 2 2 2 Emopamil binding protein MCR_beta PF02241.13 KZN89659.1 - 0.12 11.5 0.2 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain MFS_1 PF07690.11 KZN89660.1 - 1.2e-32 112.9 35.0 1.5e-32 112.7 24.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KZN89660.1 - 0.041 14.2 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 KZN89661.1 - 9.9e-104 347.9 0.0 1.2e-103 347.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN89661.1 - 2.8e-08 33.6 0.6 1.2e-07 31.4 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89661.1 - 0.0043 16.8 0.3 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ank_2 PF12796.2 KZN89662.1 - 2.3e-67 223.3 24.6 5.1e-18 65.1 0.7 5.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89662.1 - 6.2e-45 148.8 22.4 4.4e-07 29.3 0.1 13.5 12 1 1 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 KZN89662.1 - 1.1e-37 124.2 13.5 1.8e-05 24.5 0.0 13.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 KZN89662.1 - 2e-34 117.3 3.2 2.2e-10 40.7 0.0 9.3 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN89662.1 - 1.7e-22 78.9 7.5 0.00016 21.7 0.1 10.3 4 2 7 11 11 11 6 Ankyrin repeats (many copies) NACHT PF05729.7 KZN89662.1 - 9.1e-12 44.9 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN89662.1 - 1.7e-08 34.7 0.0 1.3e-07 31.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN89662.1 - 5e-07 29.9 0.1 2.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KZN89662.1 - 0.00062 18.8 0.3 0.75 8.7 0.0 2.5 1 1 1 2 2 2 2 KAP family P-loop domain AAA_11 PF13086.1 KZN89662.1 - 0.0016 18.1 0.1 0.0058 16.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN89662.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KZN89662.1 - 0.0053 16.9 0.2 0.037 14.2 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2857 PF11198.3 KZN89662.1 - 0.013 15.0 0.0 0.24 10.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) RNA_helicase PF00910.17 KZN89662.1 - 0.015 15.4 0.1 0.078 13.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KZN89662.1 - 0.024 14.5 0.1 0.47 10.3 0.1 2.6 1 1 0 1 1 1 0 AAA domain TrbL PF04610.9 KZN89662.1 - 0.22 11.1 0.0 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein HTH_32 PF13565.1 KZN89663.1 - 1.2e-07 32.4 2.1 3.8e-06 27.6 0.3 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 KZN89663.1 - 6.1e-07 29.5 0.3 7.6e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KZN89663.1 - 6.9e-05 22.8 0.5 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 KZN89663.1 - 0.00053 19.5 1.3 0.0031 17.1 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.1 KZN89663.1 - 0.0094 15.3 0.2 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF433 PF04255.9 KZN89663.1 - 0.043 13.2 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF433) HTH_38 PF13936.1 KZN89663.1 - 0.084 12.4 0.5 2.7 7.6 0.2 3.0 2 2 0 2 2 2 0 Helix-turn-helix domain HTH_39 PF14090.1 KZN89663.1 - 0.13 11.7 0.6 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sugar_tr PF00083.19 KZN89665.1 - 5.7e-113 377.8 22.8 6.5e-113 377.6 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89665.1 - 1.3e-22 79.9 41.4 2.7e-15 55.9 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NifU_N PF01592.11 KZN89666.1 - 0.07 13.0 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 NifU-like N terminal domain E1-E2_ATPase PF00122.15 KZN89667.1 - 1.5e-61 207.3 1.2 2.8e-61 206.4 0.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN89667.1 - 1.2e-34 119.4 6.5 1.2e-34 119.4 4.5 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN89667.1 - 2.1e-31 110.0 0.1 2.7e-25 90.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN89667.1 - 6.5e-18 63.9 0.0 1.8e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KZN89667.1 - 1.3e-17 63.4 0.0 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN89667.1 - 6.6e-14 52.5 0.0 1.7e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN89667.1 - 0.00018 21.1 0.8 0.0012 18.5 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1759 PF03564.10 KZN89668.1 - 0.07 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RTA1 PF04479.8 KZN89669.1 - 2.5e-40 138.3 5.4 2.5e-40 138.3 3.7 1.5 2 0 0 2 2 2 1 RTA1 like protein Lung_7-TM_R PF06814.8 KZN89669.1 - 0.0034 16.3 4.5 0.0034 16.3 3.1 1.9 2 0 0 2 2 2 1 Lung seven transmembrane receptor DUF4083 PF13314.1 KZN89669.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Peptidase_M50 PF02163.17 KZN89669.1 - 2.1 7.2 7.7 60 2.5 5.3 2.6 1 1 0 1 1 1 0 Peptidase family M50 DUF1761 PF08570.5 KZN89669.1 - 8.3 6.4 10.9 4.4 7.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) ADH_zinc_N PF00107.21 KZN89670.1 - 6.5e-23 80.6 0.9 1.1e-22 80.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN89670.1 - 1.1e-12 47.6 0.1 2.8e-11 43.1 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN89670.1 - 1.6e-11 45.1 0.2 3.4e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KZN89671.1 - 4e-11 42.2 0.8 4e-11 42.2 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN89671.1 - 0.0052 17.0 2.0 0.019 15.2 1.4 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sec10 PF07393.6 KZN89671.1 - 0.049 11.8 0.2 0.068 11.3 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Fungal_trans_2 PF11951.3 KZN89672.1 - 7.4e-12 44.5 0.5 4.1e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89672.1 - 1.2e-05 25.1 2.6 2.1e-05 24.3 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF892 PF05974.7 KZN89672.1 - 0.017 14.9 0.6 0.046 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Glyoxalase_2 PF12681.2 KZN89674.1 - 1.7e-10 41.4 0.0 2.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KZN89674.1 - 8.3e-06 25.8 0.0 0.0001 22.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Saccharop_dh PF03435.13 KZN89675.1 - 2.4e-22 79.4 0.1 6.8e-21 74.6 0.1 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase adh_short PF00106.20 KZN89675.1 - 0.0042 17.0 0.4 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DAO PF01266.19 KZN89676.1 - 1.8e-32 112.6 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN89676.1 - 5.9e-06 26.2 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89676.1 - 0.0022 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN89676.1 - 0.014 14.5 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KZN89676.1 - 0.018 15.4 0.1 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89676.1 - 0.023 14.4 0.1 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAT PF03417.11 KZN89677.1 - 3.3e-58 196.8 0.0 4e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KZN89677.1 - 2.5e-05 24.5 0.1 6.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase 2OG-FeII_Oxy PF03171.15 KZN89678.1 - 7.8e-21 74.2 0.0 6.9e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KZN89678.1 - 1.6e-15 57.6 0.1 2.5e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_20 PF00728.17 KZN89678.1 - 0.074 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain AMP-binding PF00501.23 KZN89679.1 - 1.6e-277 919.5 0.0 1.7e-96 323.2 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KZN89679.1 - 3.2e-249 824.1 10.4 2.1e-86 289.4 0.1 4.2 4 0 0 4 4 4 4 Condensation domain Thioesterase PF00975.15 KZN89679.1 - 3.1e-45 155.1 0.0 7.6e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KZN89679.1 - 2e-42 143.2 0.1 4.9e-15 55.5 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN89679.1 - 6.5e-34 116.7 0.0 1.3e-10 42.0 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KZN89679.1 - 1.2e-25 89.5 2.1 7.9e-19 67.7 0.4 3.9 3 0 0 3 3 3 3 HxxPF-repeated domain Abhydrolase_6 PF12697.2 KZN89679.1 - 0.022 14.6 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family GH3 PF03321.8 KZN89679.1 - 0.054 12.0 2.1 0.14 10.6 0.0 2.8 4 0 0 4 4 4 0 GH3 auxin-responsive promoter Abhydrolase_5 PF12695.2 KZN89679.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KZN89679.1 - 0.076 13.1 0.1 7.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Peptidase_S41 PF03572.13 KZN89680.1 - 6.8e-10 38.6 0.0 1.5e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Methyltransf_32 PF13679.1 KZN89681.1 - 2.7e-19 69.2 0.2 5.2e-19 68.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89681.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain BNIP3 PF06553.7 KZN89683.1 - 0.079 12.3 6.2 0.096 12.0 4.3 1.1 1 0 0 1 1 1 0 BNIP3 Glyco_transf_54 PF04666.8 KZN89686.1 - 3.5e-11 42.3 0.1 4.7e-09 35.3 0.1 2.8 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF606 PF04657.8 KZN89686.1 - 0.045 13.8 0.3 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF606 PSD2 PF07624.6 KZN89687.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) FAD_binding_4 PF01565.18 KZN89688.1 - 1.7e-20 72.9 2.4 4.5e-20 71.5 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KZN89688.1 - 5.6e-09 35.7 0.6 1.3e-08 34.6 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KZN89689.1 - 0.0002 20.1 31.5 0.00078 18.2 21.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily EBP PF05241.7 KZN89690.1 - 2.5e-46 157.1 13.5 1.5e-43 148.1 5.1 2.0 1 1 1 2 2 2 2 Emopamil binding protein MCR_beta PF02241.13 KZN89690.1 - 0.12 11.5 0.2 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain MFS_1 PF07690.11 KZN89691.1 - 1.2e-32 112.9 35.0 1.5e-32 112.7 24.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KZN89691.1 - 0.041 14.2 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 KZN89692.1 - 9.9e-104 347.9 0.0 1.2e-103 347.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN89692.1 - 2.8e-08 33.6 0.6 1.2e-07 31.4 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89692.1 - 0.0043 16.8 0.3 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ank_2 PF12796.2 KZN89693.1 - 2.3e-67 223.3 24.6 5.1e-18 65.1 0.7 5.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89693.1 - 6.2e-45 148.8 22.4 4.4e-07 29.3 0.1 13.5 12 1 1 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 KZN89693.1 - 1.1e-37 124.2 13.5 1.8e-05 24.5 0.0 13.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 KZN89693.1 - 2e-34 117.3 3.2 2.2e-10 40.7 0.0 9.3 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN89693.1 - 1.7e-22 78.9 7.5 0.00016 21.7 0.1 10.3 4 2 7 11 11 11 6 Ankyrin repeats (many copies) NACHT PF05729.7 KZN89693.1 - 9.1e-12 44.9 0.0 2.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN89693.1 - 1.7e-08 34.7 0.0 1.3e-07 31.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN89693.1 - 5e-07 29.9 0.1 2.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KZN89693.1 - 0.00062 18.8 0.3 0.75 8.7 0.0 2.5 1 1 1 2 2 2 2 KAP family P-loop domain AAA_11 PF13086.1 KZN89693.1 - 0.0016 18.1 0.1 0.0058 16.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN89693.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KZN89693.1 - 0.0053 16.9 0.2 0.037 14.2 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2857 PF11198.3 KZN89693.1 - 0.013 15.0 0.0 0.24 10.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) RNA_helicase PF00910.17 KZN89693.1 - 0.015 15.4 0.1 0.078 13.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KZN89693.1 - 0.024 14.5 0.1 0.47 10.3 0.1 2.6 1 1 0 1 1 1 0 AAA domain TrbL PF04610.9 KZN89693.1 - 0.22 11.1 0.0 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein HTH_32 PF13565.1 KZN89694.1 - 1.2e-07 32.4 2.1 3.8e-06 27.6 0.3 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 KZN89694.1 - 6.1e-07 29.5 0.3 7.6e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KZN89694.1 - 6.9e-05 22.8 0.5 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 KZN89694.1 - 0.00053 19.5 1.3 0.0031 17.1 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.1 KZN89694.1 - 0.0094 15.3 0.2 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding DUF433 PF04255.9 KZN89694.1 - 0.043 13.2 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF433) HTH_38 PF13936.1 KZN89694.1 - 0.084 12.4 0.5 2.7 7.6 0.2 3.0 2 2 0 2 2 2 0 Helix-turn-helix domain HTH_39 PF14090.1 KZN89694.1 - 0.13 11.7 0.6 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sugar_tr PF00083.19 KZN89696.1 - 5.7e-113 377.8 22.8 6.5e-113 377.6 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89696.1 - 1.3e-22 79.9 41.4 2.7e-15 55.9 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NifU_N PF01592.11 KZN89697.1 - 0.07 13.0 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 NifU-like N terminal domain E1-E2_ATPase PF00122.15 KZN89698.1 - 1.5e-61 207.3 1.2 2.8e-61 206.4 0.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN89698.1 - 1.2e-34 119.4 6.5 1.2e-34 119.4 4.5 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN89698.1 - 2.1e-31 110.0 0.1 2.7e-25 90.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN89698.1 - 6.5e-18 63.9 0.0 1.8e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KZN89698.1 - 1.3e-17 63.4 0.0 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN89698.1 - 6.6e-14 52.5 0.0 1.7e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN89698.1 - 0.00018 21.1 0.8 0.0012 18.5 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1759 PF03564.10 KZN89699.1 - 0.07 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) RTA1 PF04479.8 KZN89700.1 - 2.5e-40 138.3 5.4 2.5e-40 138.3 3.7 1.5 2 0 0 2 2 2 1 RTA1 like protein Lung_7-TM_R PF06814.8 KZN89700.1 - 0.0034 16.3 4.5 0.0034 16.3 3.1 1.9 2 0 0 2 2 2 1 Lung seven transmembrane receptor DUF4083 PF13314.1 KZN89700.1 - 0.83 9.5 0.0 0.83 9.5 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Peptidase_M50 PF02163.17 KZN89700.1 - 2.1 7.2 7.7 60 2.5 5.3 2.6 1 1 0 1 1 1 0 Peptidase family M50 DUF1761 PF08570.5 KZN89700.1 - 8.3 6.4 10.9 4.4 7.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) ADH_zinc_N PF00107.21 KZN89701.1 - 6.5e-23 80.6 0.9 1.1e-22 80.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN89701.1 - 1.1e-12 47.6 0.1 2.8e-11 43.1 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN89701.1 - 1.6e-11 45.1 0.2 3.4e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KZN89702.1 - 4e-11 42.2 0.8 4e-11 42.2 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN89702.1 - 0.0052 17.0 2.0 0.019 15.2 1.4 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sec10 PF07393.6 KZN89702.1 - 0.049 11.8 0.2 0.068 11.3 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Fungal_trans_2 PF11951.3 KZN89703.1 - 7.4e-12 44.5 0.5 4.1e-10 38.8 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89703.1 - 1.2e-05 25.1 2.6 2.1e-05 24.3 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF892 PF05974.7 KZN89703.1 - 0.017 14.9 0.6 0.046 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DEAD PF00270.24 KZN89705.1 - 9.4e-44 148.8 0.0 1.8e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN89705.1 - 5.2e-21 74.3 0.1 1.1e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KZN89705.1 - 8e-21 73.6 3.2 2.2e-20 72.2 2.2 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.6 KZN89706.1 - 1.3e-19 70.4 0.0 2.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KZN89706.1 - 0.0002 21.1 0.3 0.00058 19.6 0.2 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain MatE PF01554.13 KZN89707.1 - 3.1e-55 186.2 26.4 5.5e-30 104.1 6.2 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KZN89707.1 - 6.6e-06 25.9 5.3 6.6e-06 25.9 3.7 3.7 1 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 KZN89708.1 - 5.9e-21 74.4 0.7 5.9e-21 74.4 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2499 PF10693.4 KZN89708.1 - 0.027 14.5 1.4 0.045 13.8 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2499) COX4_pro_2 PF07835.7 KZN89708.1 - 0.11 12.4 0.4 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF4131 PF13567.1 KZN89708.1 - 0.22 10.9 2.5 0.43 9.9 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NUDIX PF00293.23 KZN89709.1 - 1.5e-27 95.8 0.0 2.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FMO-like PF00743.14 KZN89710.1 - 2.8e-34 118.2 0.0 1e-19 70.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN89710.1 - 1.7e-17 64.1 0.3 3.3e-16 59.9 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN89710.1 - 2.3e-08 33.9 0.3 6.4e-07 29.2 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN89710.1 - 3.4e-07 29.5 1.0 0.00014 20.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN89710.1 - 5.5e-07 29.5 0.5 1.7e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89710.1 - 6.8e-07 29.3 0.0 2.1e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN89710.1 - 5.3e-06 25.5 3.9 4.2e-05 22.6 3.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN89710.1 - 7.8e-05 22.9 3.4 0.0082 16.5 0.7 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN89710.1 - 0.00055 19.0 2.1 0.00099 18.2 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KZN89710.1 - 0.0016 17.6 0.9 0.003 16.6 0.6 1.4 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 KZN89710.1 - 0.0024 17.3 0.1 0.14 11.5 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 KZN89710.1 - 0.0077 15.3 0.3 0.022 13.8 0.1 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KZN89710.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN89710.1 - 0.022 13.2 3.6 0.038 12.4 2.5 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 KZN89710.1 - 0.03 14.1 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KZN89710.1 - 0.034 13.8 2.9 0.061 12.9 2.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KZN89710.1 - 0.036 12.9 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN89710.1 - 0.069 12.5 1.3 0.22 10.9 0.6 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KZN89710.1 - 0.13 12.3 3.1 0.77 9.8 0.6 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KZN89710.1 - 2.3 6.9 3.8 4.2 6.1 2.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-C2H2 PF00096.21 KZN89711.1 - 5.5e-12 45.2 24.3 5.3e-05 23.3 3.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN89711.1 - 1.6e-11 43.6 22.2 0.00027 21.0 2.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN89711.1 - 1.3e-10 41.0 16.5 7.7e-06 25.9 0.8 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.2 KZN89711.1 - 1e-06 28.7 12.6 0.017 15.2 1.0 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN89711.1 - 4e-06 26.8 12.7 0.017 15.2 1.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN89711.1 - 0.0018 18.1 12.6 1 9.3 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KZN89711.1 - 0.0019 18.2 4.9 0.0019 18.2 3.4 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_1g PF09334.6 KZN89711.1 - 0.17 10.4 0.5 0.25 9.9 0.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-C2HC_2 PF13913.1 KZN89711.1 - 0.73 9.5 16.5 3.1 7.5 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KZN89711.1 - 5.8 7.0 16.1 7.9 6.6 2.0 3.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 KZN89712.1 - 1.9e-24 86.2 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KZN89712.1 - 6.9e-14 51.0 9.6 1.5e-09 37.3 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.17 KZN89712.1 - 9.4e-11 40.8 5.4 0.015 15.3 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 KZN89712.1 - 1.7e-06 28.1 0.9 1.4 9.2 0.0 4.0 1 1 2 3 3 3 3 HEAT repeats Pkinase_Tyr PF07714.12 KZN89712.1 - 4e-05 22.8 0.0 7.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KZN89712.1 - 0.032 14.7 4.5 0.16 12.5 0.3 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF2454 PF10521.4 KZN89712.1 - 0.051 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) DENN PF02141.16 KZN89713.1 - 6.1e-40 136.9 0.1 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KZN89713.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KZN89713.1 - 0.013 15.9 5.8 0.013 15.9 4.0 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A IncA PF04156.9 KZN89713.1 - 0.41 10.2 25.6 0.031 13.8 4.6 3.8 1 1 2 4 4 4 0 IncA protein DivIVA PF05103.8 KZN89713.1 - 7.9 6.5 19.1 0.14 12.1 4.9 3.3 1 1 2 3 3 3 0 DivIVA protein DUF2570 PF10828.3 KZN89713.1 - 8.4 6.0 9.8 10 5.7 5.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) adh_short PF00106.20 KZN89714.1 - 2.1e-27 96.0 1.2 3.6e-27 95.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89714.1 - 2e-26 93.2 0.2 2.3e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89714.1 - 3.2e-10 39.9 0.6 1e-09 38.3 0.4 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89714.1 - 0.00024 20.6 0.1 0.00029 20.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.13 KZN89715.1 - 7.9e-42 143.1 0.0 3.7e-40 137.7 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SMC_Nse1 PF07574.8 KZN89715.1 - 0.15 11.6 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex tRNA-synt_1g PF09334.6 KZN89716.1 - 0.03 13.0 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Nsp1_C PF05064.8 KZN89717.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Zn_clus PF00172.13 KZN89718.1 - 4.1e-10 39.4 8.9 6.3e-10 38.8 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN89718.1 - 5.8e-10 38.4 0.0 8.8e-10 37.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ost4 PF10215.4 KZN89719.1 - 1.4e-18 66.0 0.9 1.9e-18 65.6 0.6 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase KOW PF00467.24 KZN89721.1 - 6.4e-06 25.6 0.4 1.5e-05 24.5 0.3 1.6 1 0 0 1 1 1 1 KOW motif Synaptobrevin PF00957.16 KZN89722.1 - 6.6e-32 108.9 0.0 9e-32 108.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KZN89722.1 - 2.7e-24 84.5 0.0 4.4e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 KZN89722.1 - 0.082 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DUF2628 PF10947.3 KZN89722.1 - 0.23 11.2 1.8 0.44 10.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) ODV-E18 PF10717.4 KZN89722.1 - 0.46 9.9 2.1 0.76 9.2 0.1 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2315 PF10231.4 KZN89723.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Toxin_36 PF10550.4 KZN89723.1 - 6.1 8.2 6.2 23 6.4 1.8 3.0 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin TPR_10 PF13374.1 KZN89724.1 - 9.3e-53 174.7 1.2 5e-10 38.9 0.0 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 KZN89724.1 - 2.8e-44 148.9 1.4 1.5e-10 40.8 0.1 6.6 3 3 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KZN89724.1 - 4.5e-10 38.5 5.8 0.72 9.8 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN89724.1 - 1e-08 34.4 3.5 17 5.6 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KZN89724.1 - 8.4e-06 26.0 1.3 0.25 11.7 0.1 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN89724.1 - 9.5e-06 25.8 8.3 1.9 9.3 0.0 6.9 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN89724.1 - 1.1e-05 25.9 1.8 0.74 10.5 0.0 5.2 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KZN89724.1 - 4.7e-05 22.9 0.1 0.48 10.1 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 KZN89724.1 - 0.00011 21.6 0.8 37 4.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 KZN89724.1 - 0.00042 20.4 13.9 0.42 11.0 0.7 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger TPR_8 PF13181.1 KZN89724.1 - 0.0018 17.8 3.8 23 5.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN89724.1 - 0.0037 17.5 0.1 4.5 7.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF629 PF04780.7 KZN89724.1 - 0.0041 15.7 0.3 0.0072 14.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 KZN89724.1 - 0.019 15.3 8.4 1.6 9.2 0.1 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 KZN89724.1 - 0.019 15.1 3.2 0.13 12.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KZN89724.1 - 0.026 14.6 6.8 11 6.1 0.3 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TPR_17 PF13431.1 KZN89724.1 - 0.027 14.6 1.4 90 3.6 0.0 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR PF01535.15 KZN89724.1 - 0.04 13.9 0.4 5.1 7.3 0.0 4.4 5 0 0 5 5 4 0 PPR repeat zf-C2H2_2 PF12756.2 KZN89724.1 - 0.087 12.9 3.2 2.1 8.4 0.1 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Bac_DnaA_C PF08299.6 KZN89724.1 - 0.11 12.3 1.1 8.4 6.3 0.0 3.6 4 0 0 4 4 3 0 Bacterial dnaA protein helix-turn-helix zf-Sec23_Sec24 PF04810.10 KZN89724.1 - 0.66 9.5 6.9 1 8.9 0.2 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger TPR_6 PF13174.1 KZN89724.1 - 0.7 10.4 6.7 25 5.6 0.1 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 KZN89728.1 - 5.7e-114 378.6 0.2 9.2e-84 279.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KZN89728.1 - 1.2e-45 154.2 0.0 2.9e-45 152.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KZN89728.1 - 1.5e-45 155.0 0.0 6.6e-45 152.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KZN89728.1 - 1.2e-42 144.9 0.0 2.4e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KZN89728.1 - 5.8e-41 139.0 0.0 3.7e-19 68.8 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 KZN89728.1 - 7.4e-40 135.5 0.0 1.7e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 KZN89728.1 - 1.9e-33 115.5 0.0 4.5e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KZN89728.1 - 9.7e-33 113.4 0.1 8.1e-20 71.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN89728.1 - 7.7e-21 74.1 0.0 2.8e-09 36.1 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KZN89728.1 - 1.9e-20 72.5 0.0 1.2e-19 70.0 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KZN89728.1 - 1.2e-15 57.5 0.6 1.7e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KZN89728.1 - 1.5e-14 53.6 0.1 4.9e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KZN89728.1 - 2.3e-07 30.4 0.1 3.9e-06 26.4 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 KZN89728.1 - 5.3e-06 26.0 0.1 0.0053 16.2 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KZN89728.1 - 1.5e-05 24.8 0.4 0.27 11.0 0.0 3.2 2 0 0 2 2 2 2 ATP-grasp domain MFS_1 PF07690.11 KZN89729.1 - 2.3e-37 128.5 22.6 2.3e-37 128.5 15.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KZN89729.1 - 3.3 7.8 12.9 15 5.7 2.5 3.6 2 1 3 5 5 5 0 NfeD-like C-terminal, partner-binding AMP-binding PF00501.23 KZN89730.1 - 7.1e-81 271.7 0.0 8.4e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN89730.1 - 6.9e-10 39.7 0.6 1.9e-09 38.3 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KZN89731.1 - 3.5e-06 27.1 0.0 4.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN89731.1 - 4.6e-05 22.9 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN89731.1 - 0.0001 21.3 0.0 0.002 17.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KZN89731.1 - 0.045 12.6 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KZN89731.1 - 0.071 11.7 0.0 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KZN89731.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KZN89731.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Vps51 PF08700.6 KZN89732.1 - 2.2e-18 65.8 1.5 5.2e-18 64.6 1.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KZN89732.1 - 0.0098 15.7 0.1 0.043 13.6 0.0 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 MAS20 PF02064.10 KZN89733.1 - 7.8e-20 71.0 0.2 2.8e-19 69.2 0.1 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor PAXIP1_C PF15364.1 KZN89733.1 - 0.12 12.3 1.2 2.9 7.7 0.3 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Toxin_39 PF15500.1 KZN89733.1 - 0.18 11.9 1.2 0.28 11.3 0.9 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin Glyco_hydro_72 PF03198.9 KZN89734.1 - 5.8e-125 416.4 1.9 7.4e-125 416.1 1.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KZN89734.1 - 0.00024 20.4 0.1 0.015 14.5 0.0 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KZN89734.1 - 0.0099 14.8 0.0 0.026 13.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AMP-binding PF00501.23 KZN89735.1 - 1.6e-85 287.0 0.0 2e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN89735.1 - 5.8e-14 52.7 2.3 1.7e-13 51.3 1.6 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 KZN89736.1 - 2.5e-09 36.7 0.2 6.1e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN89736.1 - 8.4e-08 31.6 0.3 2.1e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain Hira PF07569.6 KZN89736.1 - 0.27 10.4 0.0 0.59 9.3 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Tyrosinase PF00264.15 KZN89738.1 - 3.3e-55 187.6 2.1 6.7e-55 186.6 1.5 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Gal-bind_lectin PF00337.17 KZN89738.1 - 1.2e-09 37.5 0.0 2.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Galactoside-binding lectin Mre11_DNA_bind PF04152.9 KZN89739.1 - 1.7e-59 200.6 1.2 1.7e-59 200.6 0.8 2.0 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KZN89739.1 - 8.7e-25 87.2 1.4 1.2e-24 86.8 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN89739.1 - 3.3e-05 23.7 0.1 7.7e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KZN89739.1 - 0.068 12.3 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF1446 PF07287.6 KZN89740.1 - 7.9e-126 419.3 0.0 9.4e-126 419.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) NST1 PF13945.1 KZN89741.1 - 8.9 6.3 8.3 8.9 6.3 5.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator YihI PF04220.7 KZN89741.1 - 10 5.4 10.6 13 5.0 7.3 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Metallophos PF00149.23 KZN89742.1 - 2e-11 43.6 0.1 5.3e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN89742.1 - 1.4e-10 41.1 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 2-Hacid_dh_C PF02826.14 KZN89743.1 - 7.2e-54 181.6 0.0 9.8e-54 181.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN89743.1 - 2.6e-22 78.6 0.0 3.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN89743.1 - 1.5e-05 24.8 0.0 4.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_5 PF12695.2 KZN89744.1 - 8.6e-11 41.7 0.2 2.5e-10 40.2 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN89744.1 - 1.6e-08 34.6 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 KZN89744.1 - 0.00089 18.5 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 KZN89744.1 - 0.0032 16.7 0.1 0.28 10.3 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KZN89744.1 - 0.019 14.3 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4131 PF13567.1 KZN89745.1 - 0.03 13.7 0.1 0.083 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Methyltransf_31 PF13847.1 KZN89746.1 - 1.8e-18 66.5 0.0 2.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN89746.1 - 1.7e-17 63.6 0.0 2.7e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN89746.1 - 3.1e-16 59.5 0.0 4.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KZN89746.1 - 5.5e-13 48.6 0.0 6.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KZN89746.1 - 1.1e-12 48.0 0.1 2.2e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89746.1 - 7.9e-12 45.7 0.0 1.3e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN89746.1 - 6.6e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KZN89746.1 - 2.1e-09 36.9 0.0 3.8e-09 36.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KZN89746.1 - 2.1e-09 37.6 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN89746.1 - 2.4e-08 33.4 0.0 6.4e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 KZN89746.1 - 2e-06 27.3 0.0 3.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KZN89746.1 - 2.7e-06 26.3 0.0 3.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) UPF0020 PF01170.13 KZN89746.1 - 3.7e-06 26.6 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 KZN89746.1 - 9.6e-05 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KZN89746.1 - 0.00019 21.0 0.1 0.00038 20.0 0.1 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 KZN89746.1 - 0.00079 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.8 KZN89746.1 - 0.0073 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KZN89746.1 - 0.0075 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KZN89746.1 - 0.01 15.5 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.12 KZN89746.1 - 0.017 14.1 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase TehB PF03848.9 KZN89746.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.6 KZN89746.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 KZN89746.1 - 0.059 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 KZN89746.1 - 0.067 14.0 0.1 0.11 13.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 KZN89746.1 - 0.07 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Herpes_TAF50 PF03326.8 KZN89747.1 - 0.038 12.9 0.2 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Ribosomal_L7Ae PF01248.21 KZN89748.1 - 1.4e-24 85.3 0.0 1.8e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KZN89748.1 - 1.7e-05 24.7 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KZN89748.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Dus PF01207.12 KZN89749.1 - 1.4e-57 194.9 0.0 2e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 KZN89749.1 - 0.0078 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase WD40 PF00400.27 KZN89750.1 - 3.9e-06 26.5 0.7 0.35 10.8 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.7 KZN89750.1 - 0.02 14.5 0.3 0.83 9.3 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ERG4_ERG24 PF01222.12 KZN89752.1 - 8.2e-77 258.5 7.6 1e-76 258.2 5.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KZN89752.1 - 0.00056 20.0 0.0 0.0024 18.0 0.0 2.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KZN89752.1 - 0.00058 19.2 2.7 0.00058 19.2 1.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) p450 PF00067.17 KZN89753.1 - 1.5e-22 79.7 0.0 5.8e-21 74.5 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.1 KZN89754.1 - 4.6e-25 87.5 0.3 1.1e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 KZN89755.1 - 2.2e-31 108.9 0.0 3.2e-30 105.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KZN89756.1 - 2.8e-37 128.3 0.0 3.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.12 KZN89757.1 - 7.2e-142 472.9 11.9 8.1e-142 472.7 8.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KZN89757.1 - 3.3e-05 23.3 0.2 0.00012 21.4 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.17 KZN89759.1 - 8.2e-75 252.0 0.0 1e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAGLU_N PF12971.2 KZN89759.1 - 0.048 13.3 0.1 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Acyl-CoA_dh_M PF02770.14 KZN89759.1 - 0.12 11.8 0.2 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Aldedh PF00171.17 KZN89760.1 - 9.7e-45 152.7 1.9 2e-36 125.3 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.11 KZN89761.1 - 1.7e-31 109.1 29.0 2.3e-31 108.7 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN89761.1 - 1.4e-06 26.8 6.2 1.4e-06 26.8 4.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 KZN89762.1 - 5.9e-21 75.1 0.1 1.5e-20 73.7 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89762.1 - 9e-07 28.9 0.0 1.6e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89762.1 - 0.00028 20.5 0.1 0.003 17.2 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN89762.1 - 0.049 13.0 0.0 0.076 12.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 KZN89762.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.18 KZN89762.1 - 0.093 12.5 0.1 2 8.2 0.0 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CMD PF02627.15 KZN89763.1 - 2.8e-20 71.9 0.0 4.1e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.10 KZN89764.1 - 2e-40 138.2 0.0 3.1e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN89764.1 - 4.2e-24 84.9 0.0 5.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KZN89764.1 - 0.00015 20.6 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KZN89764.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KZN89764.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B_2 PF12706.2 KZN89765.1 - 2.6e-05 23.8 0.2 3.7e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KZN89765.1 - 0.00012 21.8 0.4 0.00024 20.8 0.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MaoC_dehydratas PF01575.14 KZN89765.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Abhydrolase_6 PF12697.2 KZN89766.1 - 4.3e-28 98.7 1.8 5.5e-28 98.3 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN89766.1 - 5.1e-17 62.2 0.0 1.3e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89766.1 - 9.1e-09 35.2 0.0 1.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KZN89766.1 - 8.1e-07 28.8 0.0 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 KZN89766.1 - 0.00076 19.2 0.0 0.0045 16.8 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 KZN89766.1 - 0.0092 14.4 0.0 0.074 11.5 0.0 1.9 2 0 0 2 2 2 1 Ndr family COesterase PF00135.23 KZN89767.1 - 9.4e-60 202.8 0.0 1.8e-58 198.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN89767.1 - 2e-08 34.0 0.1 6.7e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN89767.1 - 0.0001 22.0 0.1 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN89767.1 - 0.0006 19.7 0.1 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KZN89767.1 - 0.00095 18.6 0.1 0.0032 16.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KZN89767.1 - 0.1 11.9 0.3 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2424 PF10340.4 KZN89767.1 - 0.11 11.0 0.1 0.61 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) adh_short PF00106.20 KZN89768.1 - 4.1e-15 56.0 0.2 9e-15 54.9 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89768.1 - 2.6e-09 37.2 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89768.1 - 1e-06 28.5 0.1 3.7e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF2493 PF10686.4 KZN89768.1 - 0.008 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2493) Eno-Rase_NADH_b PF12242.3 KZN89768.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 KZN89768.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KZN89769.1 - 1.5e-47 162.4 0.0 2.1e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN89769.1 - 5e-07 28.9 0.1 0.0016 17.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN89769.1 - 7e-07 28.0 0.0 3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KZN89769.1 - 3.1e-06 27.5 0.0 0.0085 16.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89769.1 - 1.1e-05 25.3 0.2 3.5e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN89769.1 - 3.7e-05 23.8 0.0 0.0081 16.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN89769.1 - 9.8e-05 22.3 0.0 0.00037 20.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN89769.1 - 0.00021 20.3 0.1 0.0015 17.5 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KZN89769.1 - 0.00084 18.2 0.8 0.0032 16.3 0.4 1.8 1 1 1 2 2 2 1 FAD binding domain Mqo PF06039.10 KZN89769.1 - 0.0027 15.9 0.0 0.004 15.4 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 KZN89769.1 - 0.0048 16.0 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KZN89769.1 - 0.015 15.0 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KZN89769.1 - 0.019 14.0 0.4 0.91 8.5 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 KZN89769.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KZN89769.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KZN89769.1 - 0.051 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 KZN89769.1 - 0.097 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.17 KZN89770.1 - 9.5e-57 192.5 0.0 1.3e-56 192.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 KZN89771.1 - 9.1e-07 28.8 14.9 7.1e-05 22.9 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN89771.1 - 1.4e-06 28.2 11.5 0.00069 19.7 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN89771.1 - 2.9e-05 24.1 18.0 0.0008 19.5 3.3 3.6 4 0 0 4 4 4 2 Zinc-finger double domain Fungal_trans PF04082.13 KZN89771.1 - 0.00021 20.2 1.2 0.00035 19.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 KZN89773.1 - 6.7e-63 213.2 0.0 2.3e-60 204.8 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN89773.1 - 0.00027 20.5 0.0 0.0006 19.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.8 KZN89774.1 - 4.2e-149 496.5 0.0 4.9e-149 496.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Zn_clus PF00172.13 KZN89775.1 - 6.5e-06 25.9 8.6 6.5e-06 25.9 6.0 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KZN89775.1 - 0.00079 19.6 7.9 0.00079 19.6 5.5 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN89775.1 - 0.011 15.9 9.3 0.57 10.5 2.3 3.0 2 0 0 2 2 2 0 Zinc-finger double domain AMP-binding PF00501.23 KZN89776.1 - 1.4e-73 247.6 0.0 2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KZN89776.1 - 4.9e-08 33.1 0.1 1.1e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN89776.1 - 0.015 16.2 2.4 0.041 14.8 0.2 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain ATP-grasp_4 PF13535.1 KZN89777.1 - 1.2e-16 61.0 0.0 1.4e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KZN89777.1 - 0.0044 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KZN89777.1 - 0.025 13.3 0.0 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon DNA_pol3_beta_2 PF02767.11 KZN89777.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain HTH_19 PF12844.2 KZN89777.1 - 0.12 12.4 0.1 0.65 10.0 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Porphobil_deam PF01379.15 KZN89778.1 - 5.8e-40 136.5 0.0 2e-36 124.9 0.0 2.1 1 1 1 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KZN89778.1 - 3.5e-15 55.8 0.0 9.6e-15 54.4 0.1 1.7 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain p450 PF00067.17 KZN89779.1 - 5.2e-37 127.4 0.0 7.2e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KZN89779.1 - 2.3e-06 27.4 4.6 5.6e-06 26.1 3.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mur_ligase_C PF02875.16 KZN89780.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KZN89781.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Mur ligase middle domain NB-ARC PF00931.17 KZN89782.1 - 6e-11 41.7 0.0 9.1e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 KZN89782.1 - 7.3e-08 31.9 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KZN89782.1 - 7.9e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KZN89782.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KZN89782.1 - 0.0057 15.3 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Cutinase PF01083.17 KZN89782.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 KZN89782.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KZN89782.1 - 0.094 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase RicinB_lectin_2 PF14200.1 KZN89783.1 - 0.0011 19.3 0.0 0.48 10.8 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_transf_90 PF05686.7 KZN89784.1 - 3e-19 69.0 0.4 1.4e-14 53.5 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 90 Taeniidae_ag PF05596.6 KZN89784.1 - 0.0092 15.7 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 1 Taeniidae antigen NAD_binding_4 PF07993.7 KZN89785.1 - 7.7e-36 123.2 0.1 1.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN89785.1 - 6.2e-30 103.9 0.7 1.2e-29 102.9 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KZN89785.1 - 1.6e-10 40.8 0.0 4.4e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 KZN89785.1 - 6.7e-10 39.8 0.0 9.3e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN89785.1 - 7.3e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain PP-binding PF00550.20 KZN89785.1 - 6.2e-07 29.5 0.1 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AAA_18 PF13238.1 KZN89785.1 - 8.9e-05 22.8 0.0 0.00044 20.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain APS_kinase PF01583.15 KZN89785.1 - 9.1e-05 22.1 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.17 KZN89785.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Rad17 PF03215.10 KZN89785.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KZN89785.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KZN89785.1 - 0.0027 17.7 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN89785.1 - 0.0027 16.8 0.0 0.006 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NAD_binding_10 PF13460.1 KZN89785.1 - 0.0045 17.0 0.4 0.33 10.9 0.2 3.4 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 KZN89785.1 - 0.0052 16.4 0.8 0.021 14.5 0.6 2.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KZN89785.1 - 0.0089 15.9 2.0 0.039 13.8 1.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase AAA_22 PF13401.1 KZN89785.1 - 0.011 15.8 0.0 0.075 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KZN89785.1 - 0.012 15.3 0.0 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN89785.1 - 0.016 15.1 0.1 0.068 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain CoaE PF01121.15 KZN89785.1 - 0.03 13.7 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_29 PF13555.1 KZN89785.1 - 0.035 13.6 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KZN89785.1 - 0.038 14.2 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.6 KZN89785.1 - 0.053 12.2 0.0 0.094 11.3 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.17 KZN89785.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KZN89785.1 - 0.13 11.8 0.0 0.41 10.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin2 PF13189.1 KZN89785.1 - 0.14 12.0 0.0 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family 3Beta_HSD PF01073.14 KZN89785.1 - 0.2 10.3 0.0 15 4.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA_lig_kinase PF08303.6 KZN89785.1 - 0.22 11.4 0.0 0.55 10.0 0.0 1.7 1 0 0 1 1 1 0 tRNA ligase kinase domain Aldo_ket_red PF00248.16 KZN89786.1 - 4.3e-49 166.8 0.0 5.3e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 KZN89787.1 - 6.6e-27 94.0 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89787.1 - 1.5e-05 24.7 8.1 1.5e-05 24.7 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN89788.1 - 1.6e-40 138.9 27.5 2.7e-40 138.1 18.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fe-S_assembly PF04384.8 KZN89788.1 - 0.14 12.5 0.2 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Aa_trans PF01490.13 KZN89789.1 - 2.4e-35 121.8 29.2 2.8e-35 121.5 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KZN89789.1 - 0.00018 20.4 13.2 0.00018 20.4 9.2 1.9 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family Glyco_hydro_31 PF01055.21 KZN89791.1 - 6.1e-84 282.3 0.3 4.6e-83 279.4 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN89791.1 - 4.7e-14 51.9 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 KZN89792.1 - 6.6e-32 110.5 24.1 5.5e-31 107.5 16.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.3 KZN89794.1 - 0.65 9.6 13.5 0.88 9.2 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) AA_permease_2 PF13520.1 KZN89795.1 - 3.3e-54 184.0 41.4 6e-54 183.2 28.7 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN89795.1 - 1.3e-24 86.3 38.3 2.7e-24 85.3 26.5 1.4 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 KZN89796.1 - 5.2e-41 140.6 0.0 1.3e-40 139.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KZN89797.1 - 5.2e-10 39.0 12.7 1.1e-09 38.0 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KZN89798.1 - 1.5e-186 620.3 0.7 1.6e-186 620.1 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.7 KZN89799.1 - 1.5e-29 101.9 0.6 3e-29 100.9 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN89799.1 - 1.2e-23 83.0 0.1 1.2e-23 83.0 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN89799.1 - 0.0043 16.2 0.1 0.0082 15.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN89799.1 - 0.023 14.2 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 KZN89799.1 - 0.026 15.4 0.0 0.047 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Grp1_Fun34_YaaH PF01184.14 KZN89801.1 - 5.2e-26 91.2 21.4 6.9e-26 90.8 14.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1690 PF07956.6 KZN89802.1 - 0.74 9.7 5.9 1.1 9.2 3.7 1.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF1034 PF06280.7 KZN89802.1 - 2.2 8.7 5.7 10 6.5 0.2 2.4 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) Ank_2 PF12796.2 KZN89803.1 - 9.4e-16 57.9 0.4 8.2e-05 22.8 0.0 4.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN89803.1 - 3.2e-11 43.4 6.5 0.021 15.3 0.0 5.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN89803.1 - 9.8e-11 41.5 7.3 0.004 17.3 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 KZN89803.1 - 2.6e-06 26.9 12.6 0.034 13.9 0.0 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KZN89803.1 - 7.3e-06 25.7 7.6 0.016 15.4 0.0 5.9 6 1 0 6 6 6 2 Ankyrin repeat Orthopox_F14 PF06076.7 KZN89803.1 - 0.004 17.1 0.6 0.085 12.9 0.5 2.9 3 0 0 3 3 3 1 Orthopoxvirus F14 protein GST_N_3 PF13417.1 KZN89804.1 - 2.2e-11 43.8 0.0 5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN89804.1 - 4.5e-10 39.3 0.0 7.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN89804.1 - 9.8e-06 25.3 0.1 3.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN89804.1 - 0.00085 19.2 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN89804.1 - 0.0033 17.8 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PPR_1 PF12854.2 KZN89804.1 - 0.089 12.2 0.4 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 PPR repeat Abhydrolase_2 PF02230.11 KZN89805.1 - 1.1e-25 90.3 0.0 2.4e-16 59.8 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KZN89805.1 - 2.7e-05 24.1 0.0 5.6e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN89805.1 - 0.00072 19.3 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN89805.1 - 0.0069 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 KZN89805.1 - 0.031 13.4 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AF-4 PF05110.8 KZN89805.1 - 0.39 8.5 6.1 0.55 8.0 4.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein APH PF01636.18 KZN89806.1 - 3.1e-11 43.4 0.0 1.4e-10 41.3 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN89806.1 - 0.065 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.15 KZN89806.1 - 0.091 12.3 0.2 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2002 PF09400.5 KZN89807.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) APH PF01636.18 KZN89809.1 - 3.3e-10 40.0 0.3 6.9e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1014 PF06244.7 KZN89809.1 - 0.033 14.4 1.5 0.065 13.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) Adaptin_binding PF10199.4 KZN89809.1 - 0.72 10.1 7.5 0.81 9.9 3.3 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MecA PF05389.7 KZN89809.1 - 2 7.9 5.6 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Ribosomal_S25 PF03297.10 KZN89810.1 - 3.4e-39 133.1 3.5 3.7e-39 132.9 2.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KZN89810.1 - 0.013 15.1 0.1 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.7 KZN89810.1 - 0.028 13.9 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 KZN89810.1 - 0.067 13.3 0.1 0.097 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator GntR PF00392.16 KZN89810.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Cyt-b5 PF00173.23 KZN89811.1 - 6.6e-11 41.8 0.0 8.9e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NQR2_RnfD_RnfE PF03116.10 KZN89811.1 - 0.014 14.5 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family DUF473 PF04322.7 KZN89811.1 - 0.044 13.4 0.1 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF473) Gtr1_RagA PF04670.7 KZN89812.1 - 1.7e-57 194.2 0.4 8.2e-57 192.0 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KZN89812.1 - 0.048 13.2 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 KZN89813.1 - 2.5e-48 163.8 4.9 8.9e-46 155.5 3.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KZN89813.1 - 4.5e-21 74.3 0.0 1.8e-16 59.5 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KZN89813.1 - 0.0012 18.6 0.1 0.0029 17.3 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KZN89813.1 - 0.0063 16.3 0.1 0.1 12.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KZN89813.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KZN89813.1 - 0.016 15.3 0.2 0.063 13.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KZN89813.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 KZN89813.1 - 0.027 13.3 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 KZN89813.1 - 0.033 13.7 0.1 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KZN89813.1 - 0.046 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN89813.1 - 0.068 13.1 0.5 0.17 11.8 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KZN89813.1 - 0.068 13.0 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KZN89813.1 - 0.078 13.2 0.0 0.078 13.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 KZN89813.1 - 0.091 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SelP_N PF04592.9 KZN89813.1 - 0.64 9.3 5.2 5.6 6.2 1.8 2.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region adh_short PF00106.20 KZN89814.1 - 8.5e-20 71.3 0.1 6e-19 68.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN89814.1 - 2.8e-06 27.1 0.0 6.1e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN89814.1 - 7.3e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KZN89814.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KZN89814.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding His_Phos_2 PF00328.17 KZN89815.1 - 3.8e-17 62.6 0.0 3.3e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 KZN89816.1 - 5.4e-30 104.4 0.0 1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KZN89816.1 - 3.5e-23 80.8 0.0 7.5e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 KZN89816.1 - 8.1e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.16 KZN89817.1 - 1.4e-06 28.1 12.2 3.1e-06 27.0 8.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN89817.1 - 0.0065 16.2 12.9 0.0065 16.2 8.9 2.3 3 0 0 3 3 3 1 Basic region leucine zipper ABC_tran PF00005.22 KZN89818.1 - 4.4e-44 150.1 8.0 3.8e-23 82.2 0.1 3.8 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KZN89818.1 - 8.1e-20 71.9 0.3 0.00043 20.3 0.1 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KZN89818.1 - 2.4e-09 36.7 5.7 0.019 14.1 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KZN89818.1 - 2.9e-08 33.4 4.3 2.9e-08 33.4 3.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_17 PF13207.1 KZN89818.1 - 1e-06 29.5 2.9 0.0016 19.2 0.0 3.4 4 1 0 4 4 2 2 AAA domain AAA_29 PF13555.1 KZN89818.1 - 1.1e-06 28.0 1.5 0.0036 16.7 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KZN89818.1 - 1.4e-06 28.2 0.1 0.081 12.8 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase Miro PF08477.8 KZN89818.1 - 2.2e-05 24.9 0.1 0.34 11.3 0.1 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_13 PF13166.1 KZN89818.1 - 2.3e-05 23.0 3.8 0.043 12.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KZN89818.1 - 7.4e-05 22.4 0.1 0.57 9.8 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KZN89818.1 - 0.00011 22.1 3.2 0.012 15.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KZN89818.1 - 0.00012 22.2 3.7 0.48 10.5 0.0 4.1 3 2 0 3 3 3 1 AAA domain NACHT PF05729.7 KZN89818.1 - 0.00013 21.6 0.3 0.6 9.7 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KZN89818.1 - 0.00015 22.0 0.2 0.59 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KZN89818.1 - 0.00025 20.9 0.2 0.49 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KZN89818.1 - 0.00031 20.9 0.8 0.49 10.5 0.0 3.8 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KZN89818.1 - 0.0004 19.8 0.6 1.2 8.5 0.0 3.2 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 KZN89818.1 - 0.00055 19.1 1.5 0.39 9.8 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 KZN89818.1 - 0.004 17.0 0.2 5.9 6.8 0.0 3.7 4 0 0 4 4 3 0 AAA domain HlyD PF00529.15 KZN89818.1 - 0.0046 16.3 9.5 0.0046 16.3 6.6 1.8 2 0 0 2 2 2 1 HlyD family secretion protein AAA_23 PF13476.1 KZN89818.1 - 0.0065 16.8 0.2 0.16 12.2 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.1 KZN89818.1 - 0.0072 15.4 0.0 4.4 6.2 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain ArgK PF03308.11 KZN89818.1 - 0.009 14.8 0.8 3.2 6.4 0.1 2.6 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 KZN89818.1 - 0.012 15.3 1.8 4 7.0 0.0 3.0 3 0 0 3 3 2 0 Archaeal ATPase RNA_helicase PF00910.17 KZN89818.1 - 0.017 15.3 0.8 1.2 9.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.9 KZN89818.1 - 0.028 14.1 1.8 0.53 9.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KZN89818.1 - 0.042 13.3 0.5 7.6 6.0 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KZN89818.1 - 0.043 13.2 3.9 1.1 8.7 0.3 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KZN89818.1 - 0.14 12.1 13.3 3.2 7.7 1.0 3.5 2 2 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KZN89818.1 - 0.24 11.1 6.1 3.1 7.5 0.0 3.1 3 1 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KZN89818.1 - 0.28 10.6 8.0 1.6 8.1 0.1 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KZN89818.1 - 1.3 8.4 6.7 6.4 6.1 0.4 2.9 4 0 0 4 4 3 0 AAA-like domain DUF87 PF01935.12 KZN89818.1 - 1.8 8.3 14.0 1.4 8.7 0.1 3.4 5 0 0 5 5 3 0 Domain of unknown function DUF87 MoaC PF01967.16 KZN89819.1 - 1.6e-48 163.8 0.3 2.5e-48 163.1 0.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KZN89819.1 - 3.1e-35 120.6 0.0 1e-34 119.0 0.0 1.9 1 1 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KZN89819.1 - 9.3e-21 74.7 0.0 1.6e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KZN89819.1 - 0.00017 21.6 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KZN89819.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain TrkH PF02386.11 KZN89820.1 - 1.2e-76 257.5 7.5 1.7e-72 243.9 0.6 2.0 2 0 0 2 2 2 2 Cation transport protein Noc2 PF03715.8 KZN89821.1 - 2.2e-121 404.3 0.0 2.2e-121 404.3 0.0 2.2 3 1 1 4 4 4 1 Noc2p family adh_short PF00106.20 KZN89821.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 short chain dehydrogenase Nop14 PF04147.7 KZN89821.1 - 3.2 5.5 67.1 0.37 8.6 0.0 3.1 3 0 0 3 3 3 0 Nop14-like family VPS28 PF03997.7 KZN89822.1 - 1.6e-60 203.9 0.0 1.9e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Dak2 PF02734.12 KZN89822.1 - 0.012 15.2 0.2 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 DAK2 domain GvpG PF05120.7 KZN89822.1 - 0.26 11.1 2.1 0.87 9.4 0.2 2.1 2 0 0 2 2 2 0 Gas vesicle protein G Methyltransf_16 PF10294.4 KZN89823.1 - 7.9e-21 74.2 0.0 1.9e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KZN89823.1 - 0.0081 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN89823.1 - 0.025 14.6 0.1 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89823.1 - 0.027 14.0 0.0 0.078 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KZN89823.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Dyp_perox PF04261.7 KZN89824.1 - 0.00023 20.0 0.0 0.0064 15.2 0.0 3.0 2 1 0 2 2 2 1 Dyp-type peroxidase family Oxidored_q2 PF00420.19 KZN89825.1 - 0.092 12.3 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1929 PF09118.6 KZN89826.1 - 3.1e-23 81.6 0.0 6.8e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 KZN89826.1 - 4.1e-11 42.8 0.1 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Kelch_4 PF13418.1 KZN89826.1 - 2.1e-10 40.1 9.6 0.0003 20.4 0.2 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KZN89826.1 - 5.7e-08 32.6 2.8 0.0018 18.3 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KZN89826.1 - 4.7e-07 29.3 4.9 0.006 16.3 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KZN89826.1 - 1.1e-06 28.0 4.6 3.4e-05 23.2 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.6 KZN89826.1 - 1.1e-06 27.9 0.1 0.034 13.2 0.1 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_5 PF13854.1 KZN89826.1 - 0.22 11.5 5.8 1.9 8.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Mito_fiss_reg PF05308.6 KZN89827.1 - 0.015 14.6 0.3 0.026 13.9 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DEAD PF00270.24 KZN89828.1 - 8.7e-28 96.9 0.0 9.7e-27 93.5 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN89828.1 - 3.9e-23 81.1 0.1 4.5e-22 77.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN89828.1 - 0.00017 21.5 0.0 0.00079 19.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KZN89828.1 - 0.026 14.2 0.4 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain ATP-synt_G PF04718.10 KZN89829.1 - 5.9e-31 107.1 0.0 1.2e-30 106.1 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.7 KZN89830.1 - 1.5e-26 92.2 2.7 1.5e-26 92.2 1.9 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN89830.1 - 2.1e-13 49.9 0.0 4.4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KZN89830.1 - 0.0028 17.3 0.1 0.097 12.4 0.0 2.5 2 0 0 2 2 2 1 S1-like DUF2591 PF10765.4 KZN89830.1 - 0.075 13.2 0.1 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) Glyco_hydro_31 PF01055.21 KZN89831.1 - 3.1e-170 566.7 0.6 3.8e-170 566.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN89831.1 - 5.6e-12 45.3 0.3 3.7e-11 42.7 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Coq4 PF05019.8 KZN89831.1 - 0.12 11.3 0.0 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Glyco_hydro_16 PF00722.16 KZN89832.1 - 4.9e-42 143.3 3.0 4.9e-42 143.3 2.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CIA30 PF08547.7 KZN89832.1 - 0.044 13.6 0.3 0.081 12.7 0.2 1.5 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) YjcZ PF13990.1 KZN89833.1 - 0.00014 21.1 0.0 0.00032 19.9 0.0 1.6 1 1 0 1 1 1 1 YjcZ-like protein DUF4407 PF14362.1 KZN89833.1 - 0.024 13.6 0.1 0.047 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.7 KZN89833.1 - 0.043 13.6 1.0 5.4 6.8 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus tRNA-synt_2b PF00587.20 KZN89834.1 - 1.5e-46 158.1 0.0 2.6e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KZN89834.1 - 1.9e-07 30.9 0.0 4.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.14 KZN89835.1 - 1.6e-66 224.3 0.0 2.3e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KZN89835.1 - 8e-23 80.7 0.0 1.8e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sulfatase PF00884.18 KZN89836.1 - 8.3e-64 215.7 0.8 1.1e-63 215.2 0.6 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN89836.1 - 2.4e-06 27.1 0.4 6.4e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AMP-binding PF00501.23 KZN89837.1 - 1.5e-60 204.7 3.3 5.4e-23 81.0 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 KZN89837.1 - 1.5e-09 38.4 0.0 4.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 KZN89837.1 - 0.0033 17.2 0.1 0.0067 16.2 0.1 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Ribosomal_S7 PF00177.16 KZN89838.1 - 7.6e-40 135.8 0.9 9.4e-40 135.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 KZN89839.1 - 1.3e-92 310.5 36.5 3.9e-92 308.9 21.0 2.5 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KZN89839.1 - 1.7e-21 76.2 0.4 4.4e-21 74.8 0.3 1.8 1 0 0 1 1 1 1 NUC130/3NT domain UCN2 PF11613.3 KZN89839.1 - 0.43 10.5 3.1 0.49 10.3 0.4 2.4 2 0 0 2 2 2 0 Agonist of corticotropin releasing factor R2, Urocortin-2 RNR_inhib PF08591.5 KZN89840.1 - 3e-16 60.1 0.4 5.3e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor HicB PF05534.7 KZN89843.1 - 0.048 13.2 0.8 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 HicB family Herpes_capsid PF06112.6 KZN89843.1 - 0.33 11.0 9.4 0.49 10.4 6.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MAGE_N PF12440.3 KZN89843.1 - 1.9 8.8 15.7 0.092 13.0 7.0 1.6 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Gly_transf_sug PF04488.10 KZN89844.1 - 4.3e-11 43.1 0.6 9.7e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KZN89844.1 - 3.7e-05 22.4 0.1 0.0052 15.3 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DUF2293 PF10056.4 KZN89846.1 - 8.6e-30 102.5 0.2 5.3e-29 100.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) RE_BstXI PF09552.5 KZN89846.1 - 0.0038 16.3 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 2 BstXI restriction endonuclease PHD PF00628.24 KZN89847.1 - 2.4e-08 33.5 6.9 3.8e-08 32.8 4.8 1.3 1 0 0 1 1 1 1 PHD-finger DUF957 PF06117.6 KZN89847.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Mtc PF03820.12 KZN89848.1 - 2.8e-102 341.4 0.9 1.1e-101 339.5 0.7 1.7 1 1 0 1 1 1 1 Tricarboxylate carrier Amidase PF01425.16 KZN89849.1 - 5.3e-89 299.0 0.3 6.8e-89 298.7 0.2 1.1 1 0 0 1 1 1 1 Amidase Syntaxin-6_N PF09177.6 KZN89849.1 - 0.002 18.4 0.1 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Pkinase PF00069.20 KZN89850.1 - 1.3e-54 185.1 0.0 2e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN89850.1 - 3e-18 65.8 0.0 1e-17 64.1 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KZN89850.1 - 0.15 10.8 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TAF4 PF05236.9 KZN89851.1 - 7.8e-19 67.9 2.2 1.7e-12 47.2 1.0 3.1 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Form-deh_trans PF09163.6 KZN89851.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane CPSF73-100_C PF11718.3 KZN89852.1 - 4.8e-75 251.6 0.1 8e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KZN89852.1 - 5.9e-31 107.0 0.0 1.4e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KZN89852.1 - 2.2e-15 56.8 0.4 4.2e-15 55.9 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN89852.1 - 5.5e-09 35.8 0.1 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KZN89852.1 - 5.6e-07 29.2 0.2 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KZN89852.1 - 0.0051 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_3 PF00202.16 KZN89853.1 - 1.8e-87 293.3 0.0 2.3e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SRP19 PF01922.12 KZN89854.1 - 1.8e-30 105.3 0.0 2.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein FA_hydroxylase PF04116.8 KZN89858.1 - 7.8e-18 64.9 12.4 7.8e-18 64.9 8.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1973 PF09315.6 KZN89858.1 - 0.0018 17.7 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1973) DUF3606 PF12244.3 KZN89858.1 - 0.031 13.8 0.1 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) TCTP PF00838.12 KZN89859.1 - 3.4e-36 124.7 0.1 3.9e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Fungal_trans PF04082.13 KZN89860.1 - 1.3e-15 57.0 0.1 2.2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89860.1 - 3e-11 43.0 11.4 5.2e-11 42.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KZN89861.1 - 2.1e-65 217.0 3.2 3.3e-21 75.4 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN89861.1 - 1.4e-56 185.5 9.6 1.5e-07 30.8 0.0 10.9 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.1 KZN89861.1 - 1e-40 133.6 1.5 0.00012 22.0 0.0 10.9 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KZN89861.1 - 1.6e-38 130.4 10.0 8.3e-09 35.7 0.0 8.4 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN89861.1 - 1.2e-35 120.7 11.9 5.1e-06 26.5 0.0 9.3 1 1 8 9 9 9 9 Ankyrin repeats (many copies) NACHT PF05729.7 KZN89861.1 - 6.1e-07 29.2 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KZN89861.1 - 0.0014 18.7 0.1 0.0048 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SchA_CurD PF04486.7 KZN89861.1 - 0.073 12.9 0.0 0.98 9.2 0.0 2.8 3 0 0 3 3 3 0 SchA/CurD like domain Tn7_Tnp_TnsA_C PF08721.6 KZN89861.1 - 0.31 11.0 1.9 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 TnsA endonuclease C terminal Methyltransf_23 PF13489.1 KZN89862.1 - 8.6e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN89862.1 - 4.6e-08 33.6 0.0 5.9e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN89862.1 - 5.5e-05 23.5 0.0 0.00086 19.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN89862.1 - 0.00034 19.7 0.0 0.00079 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KZN89862.1 - 0.00082 18.9 0.0 0.0056 16.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN89862.1 - 0.0032 17.9 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN89862.1 - 0.04 13.9 0.0 0.21 11.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KZN89862.1 - 0.058 12.7 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KZN89862.1 - 0.17 10.9 0.0 3.2 6.7 0.0 2.4 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 KZN89862.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Glyco_hydro_3 PF00933.16 KZN89863.1 - 5.5e-70 235.7 0.0 1.4e-69 234.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN89863.1 - 5.3e-50 170.0 0.1 9.4e-50 169.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN89863.1 - 9.2e-10 38.3 0.0 3.5e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain DEAD PF00270.24 KZN89864.1 - 1.2e-32 112.7 0.0 4.9e-15 55.4 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN89864.1 - 1.8e-17 62.9 0.4 4.1e-17 61.8 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN89864.1 - 3e-06 27.2 0.0 1.2e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TRAP_alpha PF03896.11 KZN89864.1 - 0.04 12.9 4.7 0.11 11.4 3.3 1.8 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PIGA PF08288.7 KZN89865.1 - 3.9e-46 155.3 2.4 7.9e-46 154.3 0.7 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KZN89865.1 - 3.6e-29 101.3 0.0 5.5e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KZN89865.1 - 1.6e-16 60.5 0.4 3.1e-16 59.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KZN89865.1 - 4.4e-15 56.0 0.0 7.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KZN89865.1 - 2.9e-14 53.5 0.0 4.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KZN89865.1 - 6.2e-05 22.8 0.2 0.00011 21.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KZN89865.1 - 0.0019 18.4 0.0 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KZN89865.1 - 0.042 13.3 0.0 0.13 11.7 0.0 1.8 1 1 1 2 2 2 0 Starch synthase catalytic domain Arf PF00025.16 KZN89866.1 - 1.2e-39 135.3 0.0 3.7e-26 91.4 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KZN89866.1 - 5.5e-14 51.6 0.0 4.9e-07 28.7 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KZN89866.1 - 2.4e-07 31.2 0.0 2.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 KZN89866.1 - 5.5e-07 28.9 0.0 8.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN89866.1 - 2e-06 27.7 0.0 1.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KZN89866.1 - 2.4e-06 27.0 0.0 0.002 17.5 0.0 2.7 2 1 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 KZN89866.1 - 4.6e-06 26.2 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KZN89866.1 - 1.1e-05 24.7 0.0 9.3e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KZN89866.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 KZN89866.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Pyr_redox_3 PF13738.1 KZN89867.1 - 0.0011 19.0 0.0 0.0045 17.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HD PF01966.17 KZN89868.1 - 2e-06 27.8 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 HD domain Prp18 PF02840.10 KZN89869.1 - 5.6e-53 178.6 0.0 5.6e-53 178.6 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KZN89869.1 - 7.5e-07 28.3 0.5 7.5e-07 28.3 0.4 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like TMCO5 PF14992.1 KZN89869.1 - 0.16 11.0 8.6 0.33 10.0 5.9 1.5 1 0 0 1 1 1 0 TMCO5 family CDC27 PF09507.5 KZN89869.1 - 0.86 8.7 20.2 1.2 8.2 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAF-1_p150 PF11600.3 KZN89869.1 - 1.8 7.8 31.8 3.3 7.0 22.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 KZN89869.1 - 5.9 5.8 11.8 11 4.9 8.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 SAP18 PF06487.7 KZN89870.1 - 1.4e-41 141.0 0.0 1.8e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GST_N_3 PF13417.1 KZN89871.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN89871.1 - 1.9e-09 37.5 0.0 5.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN89871.1 - 2.4e-09 37.0 0.0 6.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN89871.1 - 6.5e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN89871.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN89871.1 - 0.0002 21.8 0.0 0.00052 20.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.14 KZN89872.1 - 5.7e-52 175.4 0.0 8.3e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN89872.1 - 1.9e-29 101.8 0.0 2.2e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 KZN89872.1 - 0.0021 17.6 0.1 0.053 13.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KZN89872.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ferrochelatase PF00762.14 KZN89872.1 - 0.08 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase FYVE PF01363.16 KZN89873.1 - 5.1e-15 55.1 7.9 8.1e-15 54.4 5.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 KZN89873.1 - 0.045 13.6 9.6 0.087 12.7 6.7 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.16 KZN89873.1 - 0.05 13.4 1.1 0.05 13.4 0.8 1.8 2 0 0 2 2 2 0 IBR domain Acetyltransf_1 PF00583.19 KZN89874.1 - 1.3e-08 34.7 0.0 3.1e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 KZN89874.1 - 1.6e-06 28.5 0.0 3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN89874.1 - 1.1e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN89874.1 - 0.0014 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 KZN89874.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FR47 PF08445.5 KZN89874.1 - 0.13 11.9 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Nol1_Nop2_Fmu PF01189.12 KZN89875.1 - 2.3e-11 43.5 0.0 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Ribosomal_60s PF00428.14 KZN89875.1 - 0.0037 17.6 3.5 0.018 15.4 1.9 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Polyketide_cyc2 PF10604.4 KZN89875.1 - 0.028 14.5 0.4 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport BSP_II PF05432.6 KZN89875.1 - 0.065 12.5 5.5 0.034 13.4 1.8 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BTB_2 PF02214.17 KZN89876.1 - 1e-07 32.0 1.0 0.0032 17.6 0.2 2.3 2 0 0 2 2 2 2 BTB/POZ domain GMC_oxred_N PF00732.14 KZN89877.1 - 2.8e-48 164.5 0.8 3.9e-48 164.1 0.5 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN89877.1 - 7.7e-31 107.3 0.3 7.6e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KZN89877.1 - 8.1e-07 28.2 4.6 1e-05 24.6 3.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN89877.1 - 1.4e-06 27.3 0.1 2.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KZN89877.1 - 3.4e-06 26.9 0.0 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN89877.1 - 6.8e-06 25.3 0.0 9.2e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KZN89877.1 - 1.5e-05 24.2 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN89877.1 - 6.6e-05 22.8 0.2 0.00019 21.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN89877.1 - 0.016 13.6 0.3 0.029 12.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 KZN89877.1 - 0.031 13.3 0.4 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KZN89877.1 - 0.04 12.7 0.1 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN89877.1 - 0.096 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Toxin_45 PF15524.1 KZN89877.1 - 0.1 12.7 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative toxin 45 3HCDH_N PF02737.13 KZN89877.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KZN89877.1 - 0.36 10.6 1.4 0.59 9.9 0.1 1.9 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 KZN89877.1 - 0.39 10.0 1.1 0.51 9.6 0.2 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GST_N PF02798.15 KZN89878.1 - 1.1e-12 47.9 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN89878.1 - 2.1e-11 43.6 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN89878.1 - 1.3e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN89878.1 - 2.7e-10 39.9 0.1 4.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN89878.1 - 1e-08 35.5 0.1 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KZN89878.1 - 2.1e-07 30.8 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pyr_redox PF00070.22 KZN89879.1 - 9.9e-17 61.1 0.8 7.1e-14 51.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN89879.1 - 4.4e-10 39.7 0.0 2.6e-09 37.2 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN89879.1 - 3.2e-07 30.6 0.0 0.012 15.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN89879.1 - 5.4e-06 25.5 0.4 2e-05 23.6 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KZN89879.1 - 0.013 14.4 7.6 0.25 10.1 0.2 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN89879.1 - 0.02 13.8 0.4 0.09 11.6 0.1 1.9 1 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KZN89879.1 - 0.062 13.5 0.2 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KZN89879.1 - 0.091 11.7 1.1 5.5 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain AMP-binding PF00501.23 KZN89880.1 - 3.5e-101 338.6 0.0 4.7e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN89880.1 - 1.9e-10 41.5 0.0 4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OPT PF03169.10 KZN89881.1 - 5.1e-160 533.9 44.0 5.8e-160 533.7 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 KZN89881.1 - 0.0014 18.3 0.3 0.0014 18.3 0.2 2.4 2 0 0 2 2 2 1 Heme exporter protein D (CcmD) Ppx-GppA PF02541.11 KZN89882.1 - 3e-42 144.7 0.0 8.7e-42 143.2 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Ferric_reduct PF01794.14 KZN89883.1 - 2e-22 79.5 15.6 3.8e-22 78.6 10.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN89883.1 - 5.6e-13 48.6 0.0 3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KZN89883.1 - 8e-11 42.0 0.0 2.3e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KZN89883.1 - 0.011 16.2 0.0 0.039 14.5 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Hydrophobin PF01185.13 KZN89884.1 - 1.9e-08 34.5 11.3 2.5e-08 34.2 7.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.13 KZN89885.1 - 4.8e-27 94.4 0.1 6.9e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Inhibitor_I48 PF10467.4 KZN89885.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Zn_clus PF00172.13 KZN89886.1 - 6.1e-10 38.8 6.9 1.2e-09 37.9 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN89886.1 - 5.4e-07 28.7 0.2 1.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain NPP PF08384.5 KZN89887.1 - 1.8 8.2 6.2 0.45 10.1 0.4 2.6 2 1 0 2 2 2 0 Pro-opiomelanocortin, N-terminal region MFS_1 PF07690.11 KZN89888.1 - 4.4e-16 58.5 14.6 4.4e-16 58.5 10.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.1 KZN89888.1 - 1.6 8.1 16.9 1.3 8.3 0.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CRAL_TRIO PF00650.15 KZN89890.1 - 9.1e-45 151.9 0.0 1.6e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN89890.1 - 3.4e-15 55.9 0.1 7.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KZN89890.1 - 1.5e-09 37.8 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ADP_ribosyl_GH PF03747.9 KZN89891.1 - 7.4e-57 193.3 1.4 8.4e-57 193.1 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Acetyltransf_1 PF00583.19 KZN89892.1 - 1.5e-16 60.1 0.0 2.3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN89892.1 - 3.7e-09 36.7 0.0 4.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN89892.1 - 4e-08 33.3 0.0 5.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN89892.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN89892.1 - 4.7e-05 23.3 0.0 6.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN89892.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KZN89892.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arginase PF00491.16 KZN89893.1 - 1.6e-56 191.6 0.0 3.3e-56 190.6 0.0 1.5 1 1 0 1 1 1 1 Arginase family MFS_1 PF07690.11 KZN89894.1 - 9.9e-36 123.1 24.9 1.4e-35 122.6 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN89894.1 - 2e-08 33.2 19.8 6.3e-08 31.6 13.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter GSAP-16 PF14959.1 KZN89894.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Peptidase_M24 PF00557.19 KZN89896.1 - 4e-42 144.1 0.0 5.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 KZN89896.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.13 KZN89897.1 - 6.5e-21 74.3 0.6 1.2e-20 73.5 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TauD PF02668.11 KZN89898.1 - 3.7e-25 89.0 0.1 6.7e-25 88.2 0.0 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Form_Nir_trans PF01226.12 KZN89899.1 - 7.2e-74 247.8 18.0 8.2e-74 247.6 12.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.4 KZN89899.1 - 0.001 18.8 0.4 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2107) MFS_1 PF07690.11 KZN89900.1 - 2.4e-34 118.6 29.6 2.8e-34 118.4 19.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN89900.1 - 6.4e-10 38.1 29.4 1.8e-09 36.6 12.7 1.6 1 1 1 2 2 2 2 Sugar (and other) transporter AMP-binding PF00501.23 KZN89901.1 - 3.8e-79 266.0 0.2 6.6e-79 265.2 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KZN89901.1 - 5.2e-76 255.4 0.0 2.5e-75 253.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN89901.1 - 2e-51 174.2 2.0 1.5e-50 171.3 0.0 2.7 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KZN89901.1 - 7.6e-51 173.0 0.0 1.5e-50 172.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN89901.1 - 2.4e-50 171.6 0.1 5.2e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 KZN89901.1 - 7.3e-49 166.2 0.4 1.1e-48 165.6 0.3 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KZN89901.1 - 8e-43 146.2 0.0 5e-39 133.8 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 KZN89901.1 - 4e-37 127.4 0.0 9.8e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KZN89901.1 - 9.6e-31 106.0 0.1 2.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KZN89901.1 - 9.9e-16 57.7 1.0 2.4e-07 30.8 0.0 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KZN89901.1 - 2.7e-14 53.1 0.0 2.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 KZN89901.1 - 1.2e-12 48.1 0.0 2.8e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN89901.1 - 2.4e-11 43.4 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KZN89901.1 - 3.4e-10 40.0 0.0 9.8e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 KZN89901.1 - 6e-10 39.4 0.0 1.5e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN89901.1 - 1.2e-09 38.0 0.0 3.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KZN89901.1 - 2.3e-08 33.1 0.0 1.7e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 KZN89901.1 - 4.6e-06 27.1 0.0 2e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KZN89901.1 - 7.5e-06 25.1 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NodS PF05401.6 KZN89901.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KZN89901.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAD_binding_10 PF13460.1 KZN89901.1 - 0.0029 17.6 0.0 0.009 16.0 0.0 2.0 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_16 PF10294.4 KZN89901.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Semialdhyde_dh PF01118.19 KZN89901.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GCD14 PF08704.5 KZN89901.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AATase PF07247.7 KZN89901.1 - 0.91 7.9 0.1 1.5 7.2 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase ADH_zinc_N PF00107.21 KZN89902.1 - 3e-08 33.2 0.0 4.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN89902.1 - 0.02 14.6 0.0 0.056 13.1 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 KZN89904.1 - 8.3e-05 22.4 7.7 0.00017 21.4 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KZN89905.1 - 7e-56 189.6 0.1 9.2e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.5 KZN89905.1 - 0.038 14.0 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Acyl-CoA_dh_1 PF00441.19 KZN89906.1 - 4.6e-33 114.4 1.5 7.9e-33 113.6 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN89906.1 - 7.5e-19 66.9 0.2 1.4e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN89906.1 - 3e-14 53.4 0.2 5.7e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN89906.1 - 0.0022 18.5 0.0 0.0072 16.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KZN89906.1 - 0.003 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PH_BEACH PF14844.1 KZN89906.1 - 0.039 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DUF1540 PF07561.6 KZN89906.1 - 0.078 13.0 0.3 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) AA_permease PF00324.16 KZN89907.1 - 2.8e-125 418.3 49.4 3.4e-125 418.1 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN89907.1 - 6.8e-31 107.2 53.5 8.1e-31 106.9 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 KZN89907.1 - 0.21 11.8 0.0 0.21 11.8 0.0 4.4 4 1 1 5 5 5 0 Divalent cation transporter OppC_N PF12911.2 KZN89907.1 - 0.49 9.7 4.1 0.42 10.0 0.1 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MFS_1 PF07690.11 KZN89908.1 - 1.9e-22 79.4 71.7 3.5e-18 65.4 31.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2427 PF10348.4 KZN89908.1 - 8.5 6.0 18.0 4.7 6.8 1.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Phosphoesterase PF04185.9 KZN89909.1 - 4e-76 256.6 1.5 6e-76 256.0 1.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 KZN89909.1 - 0.003 16.8 0.5 3.5 6.7 0.0 3.0 2 1 0 3 3 3 2 Sulfatase Transketolase_N PF00456.16 KZN89910.1 - 1.8e-122 408.3 0.0 2.6e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KZN89910.1 - 9e-43 145.8 0.0 1.5e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KZN89910.1 - 5.5e-08 32.0 0.0 2e-06 26.9 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KZN89910.1 - 1.2e-06 27.5 0.1 3e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 KZN89910.1 - 3.6e-06 26.9 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain ADH_N PF08240.7 KZN89911.1 - 2.1e-30 104.6 0.8 4.4e-30 103.6 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN89911.1 - 2.1e-14 53.1 0.0 3.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KZN89911.1 - 0.0038 17.3 0.7 0.093 12.7 0.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KZN89911.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans_2 PF11951.3 KZN89913.1 - 4.6e-16 58.4 4.3 7.7e-16 57.6 3.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KZN89913.1 - 0.011 14.6 1.0 0.014 14.2 0.1 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89914.1 - 9.7e-09 34.9 9.1 1.8e-08 34.1 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KZN89915.1 - 2.2e-16 60.5 0.0 1.5e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN89915.1 - 4.7e-06 25.0 0.0 0.0051 15.0 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN89915.1 - 2.7e-05 23.2 0.0 0.0031 16.4 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN89915.1 - 0.0004 20.1 0.3 0.1 12.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KZN89915.1 - 0.00058 19.7 0.0 0.0046 16.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89915.1 - 0.0065 16.4 0.1 1.7 8.7 0.2 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN89915.1 - 0.1 11.0 0.0 1.4 7.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein MHYT PF03707.11 KZN89915.1 - 0.16 12.1 0.6 0.35 11.0 0.4 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Pyridoxal_deC PF00282.14 KZN89916.1 - 5e-108 360.8 0.0 6.4e-108 360.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Epimerase PF01370.16 KZN89916.1 - 4.1e-16 59.1 0.0 8.2e-16 58.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN89916.1 - 4.7e-15 55.0 0.0 4.2e-14 51.9 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN89916.1 - 3.8e-12 46.5 0.1 9.7e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN89916.1 - 7.6e-11 41.3 0.0 4.4e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KZN89916.1 - 8.2e-06 25.2 0.1 1.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KZN89916.1 - 0.00085 19.2 0.9 0.0038 17.1 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN89916.1 - 0.00098 18.0 0.1 0.0024 16.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Beta_elim_lyase PF01212.16 KZN89916.1 - 0.0062 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase KR PF08659.5 KZN89916.1 - 0.013 15.1 0.5 0.082 12.5 0.3 2.1 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 KZN89916.1 - 0.08 11.8 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain MBOAT PF03062.14 KZN89916.1 - 0.12 11.5 0.4 0.22 10.6 0.3 1.3 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Cupin_2 PF07883.6 KZN89917.1 - 3.2e-08 32.9 0.0 5.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KZN89917.1 - 0.043 13.1 0.1 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SIR2 PF02146.12 KZN89918.1 - 2.2e-50 170.8 0.0 3.5e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Zn_clus PF00172.13 KZN89919.1 - 3.3e-08 33.2 10.0 6.1e-08 32.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN89920.1 - 1.6e-29 102.7 48.7 1e-23 83.6 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.6 KZN89920.1 - 0.017 14.6 2.3 0.39 10.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) MFS_1_like PF12832.2 KZN89920.1 - 0.31 10.8 13.1 0.044 13.5 2.5 3.0 3 0 0 3 3 3 0 MFS_1 like family Glyco_hydro_32C PF08244.7 KZN89922.1 - 8.5e-19 67.7 0.1 1.9e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KZN89922.1 - 1.6e-13 50.6 0.0 3.5e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain p450 PF00067.17 KZN89924.1 - 2.1e-61 207.8 0.0 3e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S28 PF05577.7 KZN89925.1 - 4.8e-59 200.0 2.0 1.4e-58 198.5 0.6 2.0 2 0 0 2 2 2 1 Serine carboxypeptidase S28 adh_short PF00106.20 KZN89926.1 - 4.6e-26 91.7 3.1 4.6e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KZN89926.1 - 7.8e-19 68.3 0.0 5.2e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN89926.1 - 1.3e-06 28.1 0.7 0.00076 19.1 0.4 2.2 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 KZN89926.1 - 0.047 12.7 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KZN89926.1 - 0.05 13.3 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KZN89926.1 - 0.081 12.3 0.1 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Peptidase_S10 PF00450.17 KZN89927.1 - 6.3e-91 305.6 0.0 7.8e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase NAD_binding_10 PF13460.1 KZN89928.1 - 1.5e-06 28.3 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN89928.1 - 0.00079 18.4 0.1 0.0023 16.8 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KZN89928.1 - 0.0049 17.1 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KZN89928.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 KZN89928.1 - 0.064 12.1 0.0 8.3 5.2 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 KZN89928.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN89928.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RhgB_N PF09284.5 KZN89929.1 - 4e-117 389.9 6.4 4e-117 389.9 4.4 1.5 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KZN89929.1 - 3.2e-61 205.8 0.1 3.3e-59 199.2 0.0 2.7 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KZN89929.1 - 1.1e-18 67.1 2.4 4.1e-18 65.2 1.7 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KZN89929.1 - 0.0008 19.4 0.6 0.0008 19.4 0.4 4.3 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain Amidohydro_1 PF01979.15 KZN89930.1 - 1.1e-31 110.8 0.0 1.3e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KZN89930.1 - 0.00066 18.9 1.7 0.039 13.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KZN89930.1 - 0.0036 17.0 0.0 0.0095 15.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KZN89930.1 - 0.04 13.9 0.6 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Amidohydrolase A_deaminase PF00962.17 KZN89930.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase GDC-P PF02347.11 KZN89931.1 - 5.9e-171 568.8 0.0 2.3e-159 530.6 0.0 2.4 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KZN89931.1 - 5.2e-05 22.5 0.2 9.4e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KZN89931.1 - 0.02 13.9 0.0 0.05 12.6 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 KZN89932.1 - 1e-35 123.1 31.0 1e-35 123.1 21.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.6 KZN89932.1 - 0.89 9.4 4.5 2.7 7.9 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) MFS_1 PF07690.11 KZN89933.1 - 1.4e-16 60.2 13.2 2.7e-16 59.2 8.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN89933.1 - 1.2e-10 40.5 0.4 1.2e-10 40.5 0.2 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter DUF788 PF05620.6 KZN89933.1 - 0.017 15.0 0.9 0.083 12.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF788) MFS_1 PF07690.11 KZN89934.1 - 3e-41 141.3 51.8 3e-41 141.3 35.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN89934.1 - 1.4e-10 40.3 9.5 1.4e-10 40.3 6.6 3.3 2 1 2 4 4 4 2 Sugar (and other) transporter DLH PF01738.13 KZN89935.1 - 0.0086 15.3 0.0 0.032 13.4 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family SnoaL_2 PF12680.2 KZN89935.1 - 0.026 14.9 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain SnoaL PF07366.7 KZN89935.1 - 0.033 13.7 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RIO1 PF01163.17 KZN89936.1 - 0.0013 18.1 0.0 0.0029 16.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN89936.1 - 0.0019 17.9 0.1 0.0019 17.9 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 KZN89936.1 - 0.058 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Mnd1 PF03962.10 KZN89936.1 - 1.6 8.4 4.8 6 6.4 3.3 2.0 1 0 0 1 1 1 0 Mnd1 family Hydrolase_6 PF13344.1 KZN89937.1 - 1.7e-20 72.7 0.0 2.8e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN89937.1 - 3.3e-11 42.7 0.0 2.9e-10 39.7 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like DUF4231 PF14015.1 KZN89938.1 - 0.063 13.2 0.9 0.19 11.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) YrhK PF14145.1 KZN89938.1 - 5.3 6.7 17.5 1.9 8.2 0.1 3.7 2 2 1 4 4 4 0 YrhK-like protein Sugar_tr PF00083.19 KZN89939.1 - 1.2e-91 307.6 22.6 1.4e-91 307.3 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN89939.1 - 5.1e-27 94.5 34.8 1.5e-25 89.6 11.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydantoinase_A PF01968.13 KZN89940.1 - 2.7e-83 279.4 4.9 1.4e-82 277.0 0.7 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 KZN89940.1 - 1.6e-63 214.7 0.0 2.5e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 KZN89940.1 - 5.8e-48 162.7 0.1 4.7e-45 153.2 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KZN89940.1 - 5e-05 21.8 1.6 0.16 10.2 0.1 2.4 2 0 0 2 2 2 2 MutL protein FtsA PF14450.1 KZN89940.1 - 0.0025 17.6 0.3 0.23 11.3 0.0 3.4 3 0 0 3 3 3 1 Cell division protein FtsA Ppx-GppA PF02541.11 KZN89940.1 - 0.085 12.0 0.1 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family MFS_1 PF07690.11 KZN89942.1 - 2.2e-27 95.7 34.5 1.2e-14 53.8 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 KZN89942.1 - 0.013 14.5 0.2 0.028 13.4 0.1 1.7 1 0 0 1 1 1 0 E1-E2 ATPase OATP PF03137.15 KZN89942.1 - 0.086 10.8 5.3 0.32 8.9 1.3 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KZN89942.1 - 3.5 7.5 11.4 0.97 9.2 0.1 3.8 5 0 0 5 5 5 0 MFS_1 like family p450 PF00067.17 KZN89943.1 - 7.3e-75 252.2 0.0 8.7e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 KZN89944.1 - 1.1e-32 112.8 0.0 2.4e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN89944.1 - 8.6e-27 93.1 0.0 2.5e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KZN89944.1 - 2.8e-24 84.7 0.1 4.6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KZN89944.1 - 4.1e-06 26.7 0.0 0.00053 19.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KZN89944.1 - 0.0022 17.9 0.0 0.0067 16.3 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MDMPI_N PF11716.3 KZN89944.1 - 0.0078 16.6 0.1 0.02 15.3 0.1 1.7 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain GreA_GreB PF01272.14 KZN89944.1 - 0.1 12.2 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Mid2 PF04478.7 KZN89945.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MFS_1 PF07690.11 KZN89947.1 - 1e-32 113.2 26.7 1e-32 113.2 18.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN89947.1 - 6.2e-06 25.7 3.1 2e-05 24.1 2.2 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 GDPD PF03009.12 KZN89948.1 - 0.046 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KZN89948.1 - 0.083 13.1 0.4 0.27 11.4 0.2 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family CoA_trans PF01144.18 KZN89949.1 - 3.5e-100 333.6 1.4 7.2e-61 205.1 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KZN89949.1 - 0.0041 16.8 1.2 0.0047 16.6 0.1 1.6 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Fungal_trans PF04082.13 KZN89950.1 - 6.6e-06 25.1 0.2 1.4e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C25 PF01364.13 KZN89950.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 AKAP28 PF14469.1 KZN89951.1 - 0.15 11.6 0.5 11 5.5 0.0 2.3 2 0 0 2 2 2 0 28 kDa A-kinase anchor Snf7 PF03357.16 KZN89952.1 - 1e-06 28.2 8.7 1.2e-06 28.0 6.1 1.1 1 0 0 1 1 1 1 Snf7 bZIP_2 PF07716.10 KZN89953.1 - 2.3e-11 43.3 21.1 2.6e-11 43.1 11.2 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KZN89953.1 - 5.7e-06 26.2 16.0 1.1e-05 25.2 11.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor CENP-Q PF13094.1 KZN89953.1 - 0.00092 19.2 6.3 0.0021 18.1 4.4 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_Maf PF03131.12 KZN89953.1 - 0.00093 19.4 13.7 0.00093 19.4 9.5 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor APG6 PF04111.7 KZN89953.1 - 0.26 10.2 7.8 0.4 9.6 5.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bystin PF05291.6 KZN89954.1 - 2.1e-127 424.2 0.0 2.9e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 Bystin Amidase PF01425.16 KZN89956.1 - 1.5e-115 386.6 1.2 1.8e-115 386.3 0.9 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 KZN89957.1 - 1.1e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.1 KZN89957.1 - 0.0013 18.5 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4265) ADH_N PF08240.7 KZN89957.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KZN89957.1 - 0.02 14.8 0.1 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Metallophos PF00149.23 KZN89958.1 - 3.7e-09 36.2 1.1 7.2e-09 35.3 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 KZN89959.1 - 7.1e-47 159.1 0.0 1.1e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KZN89959.1 - 9.7e-36 122.4 0.3 4.7e-35 120.2 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain zf-C2H2 PF00096.21 KZN89960.1 - 0.0046 17.2 1.2 0.009 16.3 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 KZN89960.1 - 0.0057 16.8 0.3 0.0093 16.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KZN89960.1 - 0.01 16.1 0.4 0.021 15.1 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KZN89960.1 - 0.05 13.7 0.2 0.075 13.1 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KZN89960.1 - 0.061 13.2 0.6 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN89960.1 - 0.067 13.3 2.2 0.11 12.7 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1691 PF07950.6 KZN89961.1 - 7.6e-50 167.4 9.4 1.3e-32 112.0 3.4 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) VirB8 PF04335.8 KZN89961.1 - 0.21 11.1 1.1 0.35 10.4 0.7 1.2 1 0 0 1 1 1 0 VirB8 protein TRM PF02005.11 KZN89962.1 - 4.4e-114 381.3 0.0 6.5e-99 331.3 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KZN89962.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 KZN89962.1 - 0.00031 20.3 0.0 0.00078 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2067 PF09840.4 KZN89962.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Trypan_PARP PF05887.6 KZN89962.1 - 0.0094 15.7 10.8 0.031 14.0 3.3 2.4 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Methyltransf_18 PF12847.2 KZN89962.1 - 0.069 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KZN89962.1 - 0.11 11.8 0.0 0.34 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KZN89962.1 - 0.15 11.1 0.1 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3306 PF11748.3 KZN89962.1 - 0.35 11.5 9.7 0.058 14.0 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SpaB_C PF14028.1 KZN89962.1 - 0.8 9.2 5.2 0.26 10.8 0.4 2.0 2 0 0 2 2 2 0 SpaB C-terminal domain DUF2360 PF10152.4 KZN89962.1 - 7.4 6.8 11.2 13 6.0 2.1 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Acyl_transf_1 PF00698.16 KZN89963.1 - 4.8e-83 279.1 0.0 4.6e-81 272.6 0.0 3.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KZN89963.1 - 1.5e-39 134.1 0.0 3.6e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KZN89963.1 - 5.1e-31 106.2 0.1 1.8e-30 104.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KZN89963.1 - 1.3e-19 70.3 0.0 4.5e-19 68.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short_C2 PF13561.1 KZN89964.1 - 7.1e-22 78.3 0.0 1.9e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KZN89964.1 - 1e-20 74.2 0.1 3.1e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KZN89964.1 - 3.8e-19 68.6 0.1 8.7e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KZN89964.1 - 3.5e-11 43.0 1.2 7.7e-11 41.8 0.0 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KZN89964.1 - 5e-06 26.5 0.0 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN89964.1 - 0.0015 18.2 0.0 0.0047 16.5 0.0 1.9 1 0 0 1 1 1 1 KR domain TFIIF_alpha PF05793.7 KZN89965.1 - 7e-08 31.2 56.0 1.9e-07 29.8 4.2 3.1 1 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) OPT PF03169.10 KZN89966.1 - 1.4e-201 671.1 37.6 1.7e-201 670.9 26.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF383 PF04063.9 KZN89967.1 - 3.2e-74 248.6 0.5 1.3e-73 246.7 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KZN89967.1 - 2.3e-23 81.4 1.8 3.1e-22 77.9 0.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF384) SMK-1 PF04802.10 KZN89967.1 - 0.0094 15.4 0.4 1.1 8.7 0.0 2.4 1 1 0 2 2 2 2 Component of IIS longevity pathway SMK-1 HEAT_2 PF13646.1 KZN89967.1 - 0.12 12.7 0.7 3.5 7.9 0.2 3.0 2 1 0 2 2 2 0 HEAT repeats Inositol_P PF00459.20 KZN89968.1 - 2.3e-65 220.6 0.0 2.7e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 KZN89969.1 - 7.5e-42 143.0 0.1 1.8e-27 96.1 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KZN89969.1 - 0.00055 19.5 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KZN89969.1 - 0.0038 16.9 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KZN89969.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 KZN89969.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DAGK_cat PF00781.19 KZN89970.1 - 1.4e-12 47.1 0.0 2.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.17 KZN89971.1 - 4.2e-119 397.9 0.0 5.3e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KZN89971.1 - 1.1e-05 24.9 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 KZN89972.1 - 1.3e-84 282.9 0.0 2.4e-84 282.1 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KZN89972.1 - 3.4e-17 61.5 26.7 0.0003 20.5 0.2 8.8 9 0 0 9 9 9 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KZN89972.1 - 0.16 10.2 0.2 0.65 8.2 0.0 2.0 2 1 1 3 3 3 0 Cytochrome D1 heme domain XPG_I_2 PF12813.2 KZN89973.1 - 3e-85 285.6 0.0 3.9e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KZN89973.1 - 0.00037 20.4 0.1 0.00085 19.3 0.1 1.5 1 0 0 1 1 1 1 XPG I-region Fcf1 PF04900.7 KZN89974.1 - 1e-38 131.4 0.1 1e-38 131.4 0.1 1.6 2 0 0 2 2 2 1 Fcf1 IF-2B PF01008.12 KZN89975.1 - 4.7e-73 245.6 4.1 5.4e-73 245.4 2.9 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LSM PF01423.17 KZN89976.1 - 1.2e-18 66.4 0.1 1.3e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN89976.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Rad60-SLD PF11976.3 KZN89977.1 - 2.4e-21 75.1 0.1 4.2e-18 64.7 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KZN89977.1 - 0.001 18.3 0.0 0.027 13.8 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family Trm112p PF03966.11 KZN89978.1 - 3.5e-15 56.1 0.0 4.2e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 KZN89978.1 - 0.046 13.9 0.5 0.087 13.0 0.4 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 KZN89978.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain N-SET PF11764.3 KZN89979.1 - 3e-47 160.6 1.4 3e-47 160.6 0.9 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 KZN89979.1 - 3e-24 84.0 0.7 5.9e-24 83.1 0.5 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 KZN89979.1 - 7.8e-24 84.8 0.2 7.8e-24 84.8 0.2 3.3 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 KZN89979.1 - 0.00026 20.5 0.0 0.00055 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 KZN89981.1 - 1.1e-11 44.1 0.2 1.7e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89981.1 - 2e-10 40.4 10.2 3.6e-10 39.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 KZN89982.1 - 1.1e-40 139.4 47.0 1.1e-40 139.4 32.6 3.2 2 1 1 3 3 3 1 Amino acid permease MFS_1 PF07690.11 KZN89982.1 - 7.6e-30 103.8 48.5 7.6e-30 103.8 33.6 5.4 2 2 1 3 3 3 1 Major Facilitator Superfamily AA_permease PF00324.16 KZN89982.1 - 6.8e-21 74.1 40.0 6.8e-21 74.1 27.7 2.7 2 0 0 2 2 2 1 Amino acid permease Pyr_redox_3 PF13738.1 KZN89982.1 - 4e-11 43.3 0.0 1.5e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN89982.1 - 1.7e-05 23.9 0.0 3.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN89982.1 - 0.049 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN89983.1 - 1.6e-11 43.7 0.0 2.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peptidase_C93 PF06035.6 KZN89983.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Cupin_3 PF05899.7 KZN89984.1 - 2.5e-10 39.5 0.3 3.7e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KZN89984.1 - 1e-05 24.9 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KZN89984.1 - 0.00039 20.0 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding_2 PF14525.1 KZN89984.1 - 0.0054 16.3 0.0 0.0072 15.9 0.0 1.1 1 0 0 1 1 1 1 AraC-binding-like domain EutQ PF06249.7 KZN89984.1 - 0.0057 16.2 0.1 0.0069 15.9 0.1 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 KZN89984.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain CENP-C_C PF11699.3 KZN89984.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like Zn_clus PF00172.13 KZN89985.1 - 2.6e-08 33.6 7.5 5.1e-08 32.7 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KZN89986.1 - 2.8e-51 174.4 0.0 3.7e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN89986.1 - 6.7e-34 117.2 0.0 1.1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN89986.1 - 3.1e-05 23.0 0.1 5.4e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN89986.1 - 0.00051 19.0 0.1 0.00082 18.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KZN89986.1 - 0.0066 15.3 0.4 1.9 7.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KZN89986.1 - 0.088 12.8 0.1 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89986.1 - 0.16 12.0 0.2 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN89986.1 - 0.18 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 KZN89987.1 - 3e-36 124.8 0.8 3.6e-36 124.5 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN89987.1 - 2e-08 34.0 10.0 2e-08 34.0 6.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KZN89988.1 - 7.6e-25 88.1 0.0 2.2e-24 86.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN89988.1 - 2.8e-13 48.9 0.0 6.1e-13 47.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN89988.1 - 1.5e-07 31.2 0.0 4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN89988.1 - 5e-07 28.9 0.0 1.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN89988.1 - 3.7e-06 26.9 0.0 0.017 15.0 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN89988.1 - 0.00011 21.2 0.0 0.00027 19.9 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KZN89988.1 - 0.00064 18.8 0.7 0.94 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN89988.1 - 0.0021 17.0 0.2 0.076 11.8 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN89988.1 - 0.0049 15.7 0.1 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KZN89988.1 - 0.0078 15.1 0.9 1.3 7.7 0.1 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN89988.1 - 0.016 14.9 1.6 2.4 7.9 0.1 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 KZN89988.1 - 0.016 14.2 0.1 0.038 13.0 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Integrin_b_cyt PF08725.6 KZN89988.1 - 0.042 13.2 0.3 0.094 12.1 0.2 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain 2-Hacid_dh_C PF02826.14 KZN89988.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SbcCD_C PF13558.1 KZN89988.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FAD_oxidored PF12831.2 KZN89988.1 - 0.48 9.4 2.9 0.97 8.4 1.1 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Cupin_3 PF05899.7 KZN89989.1 - 2e-07 30.3 0.3 2.8e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KZN89989.1 - 0.00067 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Big_2 PF02368.13 KZN89989.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) CENP-C_C PF11699.3 KZN89989.1 - 0.082 12.8 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like p450 PF00067.17 KZN89990.1 - 2.9e-43 148.0 0.0 3.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 KZN89991.1 - 9.3e-183 607.7 0.3 1e-182 607.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN89991.1 - 4.3e-06 25.7 0.0 6.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DAO PF01266.19 KZN89992.1 - 7.3e-48 163.2 0.1 8.6e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN89992.1 - 0.0028 17.7 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN89992.1 - 0.005 16.8 0.3 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN89992.1 - 0.024 14.4 0.1 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN89992.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aldedh PF00171.17 KZN89993.1 - 1.1e-156 521.8 0.4 1.2e-156 521.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NmrA PF05368.8 KZN89994.1 - 2.6e-27 95.5 0.0 3.4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN89994.1 - 1.4e-07 31.6 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KZN89994.1 - 9.5e-05 22.6 0.0 0.00021 21.5 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KZN89994.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 KZN89994.1 - 0.0018 18.2 0.0 0.0065 16.4 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.20 KZN89994.1 - 0.0021 18.0 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KZN89994.1 - 0.0024 17.3 0.0 0.0094 15.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN89994.1 - 0.005 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 KR domain DapB_N PF01113.15 KZN89994.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KZN89994.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aldedh PF00171.17 KZN89995.1 - 2.4e-180 599.8 1.5 2.7e-180 599.6 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Semialdhyde_dh PF01118.19 KZN89995.1 - 0.0081 16.4 0.3 3.8 7.8 0.0 3.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Lantibiotic_a PF14867.1 KZN89995.1 - 0.055 12.7 0.2 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Lantibiotic alpha Oxidored_FMN PF00724.15 KZN89996.1 - 6.6e-43 147.0 0.0 9e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SIS PF01380.17 KZN89998.1 - 4.5e-55 184.8 0.0 5.7e-29 100.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KZN89998.1 - 2.5e-28 98.8 0.0 3.7e-19 68.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KZN89998.1 - 2e-19 69.8 0.0 4.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KZN89998.1 - 1.4e-12 47.4 0.0 3.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KZN89998.1 - 2.6e-08 32.8 0.1 5.7e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DMRL_synthase PF00885.14 KZN89999.1 - 1.5e-45 154.4 0.3 8.9e-26 90.2 0.0 2.0 1 1 1 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 KZN90000.1 - 1e-46 158.6 0.7 1.8e-32 112.1 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 KZN90000.1 - 8.4e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF4157 PF13699.1 KZN90001.1 - 0.033 14.3 0.5 0.083 13.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) HNF-1A_C PF04813.7 KZN90001.1 - 1.6 9.0 7.7 2.7 8.2 2.5 2.4 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF1059 PF06348.6 KZN90002.1 - 0.026 14.3 0.6 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Iso_dh PF00180.15 KZN90003.1 - 1.3e-84 284.1 0.0 1.6e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 KZN90004.1 - 6.5e-17 61.8 0.3 1.2e-16 60.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KZN90004.1 - 3.2e-11 43.5 0.0 6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN90004.1 - 9.8e-10 38.7 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90004.1 - 6.5e-07 29.0 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN90004.1 - 5.7e-06 26.8 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN90004.1 - 5.7e-06 26.7 0.0 1.8e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN90004.1 - 2.9e-05 24.0 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN90004.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KZN90004.1 - 0.00028 20.5 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KZN90004.1 - 0.0019 17.3 0.0 0.0053 15.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KZN90004.1 - 0.048 12.7 0.0 0.75 8.8 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 KZN90005.1 - 6.4e-91 303.4 0.0 7.2e-91 303.2 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 RhoGAP PF00620.22 KZN90006.1 - 6.5e-41 139.4 0.1 1.3e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KZN90006.1 - 6.8e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KZN90006.1 - 1.7e-07 31.5 0.0 3.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KZN90006.1 - 0.0038 17.2 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3450 PF11932.3 KZN90006.1 - 0.03 13.5 0.6 0.066 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MDM31_MDM32 PF08118.6 KZN90007.1 - 5.6e-197 655.1 0.3 6.6e-197 654.9 0.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 KZN90007.1 - 0.1 12.0 0.1 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 TraH_2 KH_1 PF00013.24 KZN90008.1 - 0.00019 21.0 1.8 0.00038 20.0 1.2 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 KZN90009.1 - 1.2e-32 112.7 0.6 2.3e-31 108.5 0.4 2.1 1 1 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 KZN90010.1 - 1.8e-32 111.2 0.5 2.5e-32 110.7 0.3 1.2 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 KZN90012.1 - 1.1e-27 96.5 0.0 1.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 KZN90013.1 - 2e-62 210.5 0.0 2.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 KZN90014.1 - 1.6e-17 63.2 0.1 4.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Autophagy_act_C PF03987.10 KZN90016.1 - 3.9e-15 55.7 0.1 6.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 KZN90017.1 - 3.1e-10 39.7 0.1 4.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN90017.1 - 2.2e-08 33.5 0.1 4.5e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90017.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KZN90017.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Calcipressin WD40 PF00400.27 KZN90018.1 - 9.2e-21 72.9 10.1 1.1e-08 34.6 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KZN90018.1 - 0.00094 18.4 0.1 0.0036 16.5 0.0 1.8 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 KZN90018.1 - 0.093 11.3 0.3 17 3.8 0.0 3.2 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF2388 PF09498.5 KZN90018.1 - 0.12 11.9 0.7 0.37 10.4 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2388) Lipase_3 PF01764.20 KZN90019.1 - 1.3e-28 99.3 0.0 1.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KZN90019.1 - 0.0098 15.6 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN90019.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN90019.1 - 0.039 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.3 KZN90019.1 - 0.081 12.2 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 KZN90019.1 - 0.098 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold WW PF00397.21 KZN90020.1 - 4.5e-09 35.9 0.3 1.3e-08 34.5 0.2 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KZN90020.1 - 0.0079 14.8 0.6 0.012 14.1 0.4 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase APH PF01636.18 KZN90021.1 - 1.1e-13 51.4 0.0 3.4e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 KZN90022.1 - 5.4e-18 64.7 5.7 7.2e-18 64.3 4.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.2 KZN90023.1 - 1.6e-158 528.3 0.0 4.9e-157 523.4 0.0 2.8 3 0 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 KZN90023.1 - 3.9e-05 23.9 0.5 0.041 14.2 0.0 5.1 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KZN90023.1 - 5.5e-05 22.9 3.5 9.6 6.5 0.1 8.1 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KZN90023.1 - 0.00068 20.0 15.9 0.22 12.0 0.0 7.8 9 0 0 9 9 9 2 HEAT-like repeat SNF2_N PF00176.18 KZN90024.1 - 8.2e-52 175.8 0.0 2e-51 174.5 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 KZN90024.1 - 5.8e-08 32.2 8.5 1.5e-07 30.9 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN90024.1 - 2.2e-07 30.5 10.1 5.2e-07 29.3 7.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN90024.1 - 2.2e-06 27.2 7.8 2.2e-06 27.2 5.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN90024.1 - 1.4e-05 24.9 9.7 3.8e-05 23.6 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN90024.1 - 0.00016 21.7 4.7 0.00038 20.5 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KZN90024.1 - 0.00016 21.3 8.4 0.00016 21.3 5.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Nucleoplasmin PF03066.10 KZN90024.1 - 0.0023 17.4 0.0 0.0072 15.8 0.0 1.8 1 0 0 1 1 1 1 Nucleoplasmin Helicase_C PF00271.26 KZN90024.1 - 0.006 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 KZN90024.1 - 0.0064 16.0 4.7 0.015 14.8 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 TPR_2 PF07719.12 KZN90024.1 - 0.014 15.3 0.6 0.05 13.5 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 KZN90024.1 - 0.023 14.6 0.6 0.072 13.0 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 KZN90024.1 - 0.048 13.5 8.0 0.1 12.4 5.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN90024.1 - 0.11 12.2 3.5 0.3 10.8 2.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PNGaseA PF12222.3 KZN90025.1 - 1.9e-158 527.8 3.2 1.3e-156 521.7 2.2 2.1 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.6 KZN90026.1 - 2.2e-64 216.7 6.0 2.8e-64 216.4 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CLAMP PF14769.1 KZN90026.1 - 0.12 12.4 0.7 0.65 10.1 0.1 2.3 2 1 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 PMM PF03332.8 KZN90027.1 - 5.1e-101 336.8 0.3 5.9e-101 336.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KZN90027.1 - 0.00027 20.5 0.0 0.00059 19.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KZN90027.1 - 0.0067 15.7 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 KZN90027.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DnaJ PF00226.26 KZN90029.1 - 5.1e-11 42.1 2.4 2.1e-10 40.1 1.2 2.4 2 1 0 2 2 2 1 DnaJ domain LZ_Tnp_IS66 PF13007.2 KZN90029.1 - 1.1 10.0 4.9 3.3 8.4 1.2 2.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain PRA1 PF03208.14 KZN90030.1 - 1e-40 138.6 2.3 1.1e-40 138.4 1.6 1.0 1 0 0 1 1 1 1 PRA1 family protein E1-E2_ATPase PF00122.15 KZN90030.1 - 0.16 11.0 0.2 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase Frag1 PF10277.4 KZN90032.1 - 1.6e-42 145.3 11.2 1.9e-42 145.1 7.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3353 PF11833.3 KZN90032.1 - 0.0022 17.4 0.1 0.0056 16.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) Tetraspannin PF00335.15 KZN90032.1 - 0.0062 15.8 6.9 0.0062 15.8 4.8 1.9 2 0 0 2 2 2 1 Tetraspanin family DUF998 PF06197.8 KZN90032.1 - 0.17 11.1 17.0 0.018 14.3 6.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3671 PF12420.3 KZN90032.1 - 6.5 6.7 9.9 0.51 10.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function Y_phosphatase3 PF13350.1 KZN90033.1 - 8e-31 107.5 0.5 9.9e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KZN90033.1 - 4.1e-07 29.5 0.0 9.2e-07 28.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KZN90033.1 - 1.7e-05 24.8 0.1 4e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KZN90033.1 - 0.0085 15.4 0.1 0.017 14.4 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 KZN90033.1 - 0.015 14.8 0.0 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 KZN90033.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Cut8_N PF14482.1 KZN90033.1 - 1.6 8.8 6.2 0.54 10.2 2.3 1.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Glyco_hydro_35 PF01301.14 KZN90034.1 - 4.6e-75 252.9 4.1 6.4e-75 252.4 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KZN90034.1 - 2e-59 200.0 4.1 4.8e-59 198.7 2.8 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KZN90034.1 - 5.4e-51 171.5 1.4 2.3e-25 88.9 0.6 3.3 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KZN90034.1 - 3e-25 87.4 0.2 7.6e-25 86.1 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Ank_2 PF12796.2 KZN90035.1 - 1e-55 185.9 9.1 2.3e-16 59.9 0.1 5.4 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90035.1 - 2e-45 150.3 16.3 4.3e-06 26.2 0.0 10.1 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KZN90035.1 - 1.2e-38 130.8 7.4 1.5e-07 31.7 0.1 8.8 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90035.1 - 9.9e-34 112.0 8.2 0.00046 20.1 0.0 9.6 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KZN90035.1 - 2.8e-31 106.8 16.2 8e-09 35.4 0.3 6.8 3 3 5 8 8 8 6 Ankyrin repeats (many copies) DUF3812 PF12757.2 KZN90036.1 - 5.9e-39 132.9 13.3 5.9e-39 132.9 9.3 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3812) Glyco_hydro_18 PF00704.23 KZN90037.1 - 1e-78 265.1 5.0 1.7e-78 264.4 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KZN90037.1 - 2.3e-10 40.2 17.7 2.3e-10 40.2 12.3 6.4 7 0 0 7 7 7 2 Chitin recognition protein Pneumo_att_G PF05539.6 KZN90038.1 - 0.11 11.8 6.2 0.14 11.4 4.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G LysM PF01476.15 KZN90039.1 - 7.2e-11 41.8 0.0 0.0025 17.6 0.0 3.3 3 0 0 3 3 3 3 LysM domain Fib_alpha PF08702.5 KZN90040.1 - 0.0068 16.5 0.6 0.025 14.7 0.1 1.9 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Peptidase_M91 PF14891.1 KZN90040.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Effector protein Iron_traffic PF04362.9 KZN90040.1 - 0.055 12.8 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Aspzincin_M35 PF14521.1 KZN90040.1 - 0.12 12.8 1.9 6.3 7.2 0.0 3.0 2 1 2 4 4 4 0 Lysine-specific metallo-endopeptidase Ank_2 PF12796.2 KZN90041.1 - 8.7e-57 189.4 0.1 2.7e-18 66.0 0.1 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90041.1 - 1.2e-36 122.6 5.4 9.5e-06 25.1 0.0 9.2 8 1 1 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KZN90041.1 - 2.2e-24 85.3 4.6 5.9e-11 42.5 0.2 7.7 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90041.1 - 1e-23 80.9 5.2 0.0015 18.5 0.1 9.0 8 1 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 KZN90041.1 - 8e-20 70.4 4.1 1.1e-08 35.0 0.1 7.4 6 2 3 9 9 9 5 Ankyrin repeats (many copies) F-box PF00646.28 KZN90041.1 - 0.015 14.9 1.2 0.03 13.9 0.8 1.5 1 0 0 1 1 1 0 F-box domain WD40 PF00400.27 KZN90042.1 - 3.1e-18 64.9 6.7 1.4e-11 43.7 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat MFS_1 PF07690.11 KZN90043.1 - 2.7e-31 108.5 19.9 2.7e-31 108.5 13.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90043.1 - 1.7e-10 40.0 11.2 1.7e-10 40.0 7.7 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter CBFD_NFYB_HMF PF00808.18 KZN90044.1 - 5.1e-29 100.1 0.6 6.8e-29 99.7 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KZN90044.1 - 5.8e-07 29.5 0.0 8.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KZN90044.1 - 0.00021 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 KZN90044.1 - 0.00044 19.9 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CFEM PF05730.6 KZN90045.1 - 2.4e-11 43.2 13.1 5.5e-11 42.1 9.1 1.6 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 KZN90045.1 - 0.022 13.4 2.9 0.022 13.4 2.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.12 KZN90045.1 - 0.71 9.6 25.0 1 9.1 17.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF793 PF05633.6 KZN90045.1 - 1.7 7.3 4.4 1.7 7.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Ilm1 PF10311.4 KZN90046.1 - 5.3e-47 159.3 6.0 1.5e-46 157.9 4.1 1.6 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 KZN90047.1 - 1.2e-33 114.2 13.3 5.5e-07 29.0 0.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KZN90047.1 - 2.9e-22 79.1 0.0 3e-16 59.8 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KZN90047.1 - 3.5e-05 23.7 0.0 0.005 16.8 0.0 3.4 3 1 0 3 3 3 1 Prenyltransferase-like Pkinase PF00069.20 KZN90048.1 - 1.6e-68 230.6 0.0 1.6e-68 230.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90048.1 - 1.2e-42 145.7 0.0 1.8e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN90048.1 - 1e-09 37.8 0.0 4.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN90048.1 - 0.001 18.1 0.1 0.0078 15.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN90048.1 - 0.0051 16.5 5.0 1.3 8.7 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 KZN90048.1 - 1.4 8.2 4.9 0.7 9.2 0.0 2.5 3 0 0 3 3 3 0 RIO1 family MFS_1 PF07690.11 KZN90049.1 - 5e-15 55.0 40.4 5.9e-15 54.8 24.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90049.1 - 0.00028 19.5 7.6 0.00028 19.5 5.2 2.8 1 1 2 3 3 3 1 Sugar (and other) transporter E1-E2_ATPase PF00122.15 KZN90050.1 - 1.2e-63 214.2 5.5 6.1e-63 211.9 3.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN90050.1 - 3e-46 157.2 6.0 3e-46 157.2 4.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN90050.1 - 3.6e-31 109.2 0.0 2.7e-30 106.3 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN90050.1 - 6e-20 71.0 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KZN90050.1 - 1.7e-19 69.0 0.1 5.2e-19 67.4 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KZN90050.1 - 6.3e-18 65.6 0.3 3.3e-17 63.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN90050.1 - 4.4e-07 29.7 1.7 2.3e-05 24.1 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN90050.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase eIF3_subunit PF08597.5 KZN90052.1 - 1.7e-70 237.4 26.4 1.9e-70 237.2 18.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit IRF PF00605.12 KZN90052.1 - 0.2 11.4 8.3 0.076 12.8 2.5 2.2 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor ATC_hydrolase PF14196.1 KZN90052.1 - 0.59 10.5 0.1 0.59 10.5 0.0 2.2 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Nop53 PF07767.6 KZN90052.1 - 0.61 9.0 30.2 0.031 13.2 15.0 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) RepB-RCR_reg PF10723.4 KZN90052.1 - 0.84 9.4 10.9 3.2 7.5 1.7 2.8 2 1 0 2 2 2 0 Replication regulatory protein RepB FNIP_N PF14636.1 KZN90052.1 - 1.4 9.4 7.7 0.57 10.6 2.3 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus SpoVR PF04293.8 KZN90052.1 - 4.9 5.4 9.1 9.3 4.4 6.3 1.4 1 0 0 1 1 1 0 SpoVR like protein Enolase_C PF00113.17 KZN90053.1 - 9.8e-152 504.0 0.0 1.3e-151 503.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KZN90053.1 - 2e-57 192.7 0.5 3.8e-57 191.8 0.1 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 KZN90053.1 - 0.023 13.6 0.3 0.75 8.6 0.0 2.6 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KZN90053.1 - 0.034 14.6 0.0 0.083 13.4 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain AAA PF00004.24 KZN90054.1 - 9.6e-43 145.5 0.0 1.6e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN90054.1 - 9.7e-08 32.2 0.0 5.2e-06 26.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KZN90054.1 - 1.9e-06 27.6 0.1 4.3e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN90054.1 - 4e-06 26.8 0.0 1.6e-05 24.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KZN90054.1 - 6.7e-06 26.2 0.0 0.0033 17.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KZN90054.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KZN90054.1 - 0.00021 20.2 0.0 0.00059 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KZN90054.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KZN90054.1 - 0.0015 17.3 0.2 0.0038 15.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KZN90054.1 - 0.0024 18.6 0.2 0.0076 17.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN90054.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KZN90054.1 - 0.0029 17.4 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KZN90054.1 - 0.005 17.0 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 KZN90054.1 - 0.005 16.0 0.0 0.0095 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KZN90054.1 - 0.0055 16.1 0.1 0.03 13.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KZN90054.1 - 0.0064 15.9 0.0 0.021 14.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 KZN90054.1 - 0.0074 15.3 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KZN90054.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KZN90054.1 - 0.009 15.6 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN90054.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KZN90054.1 - 0.019 14.5 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KZN90054.1 - 0.024 14.7 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KZN90054.1 - 0.026 13.6 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 KZN90054.1 - 0.028 14.3 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain eIF-1a PF01176.14 KZN90054.1 - 0.032 13.6 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 PhoH PF02562.11 KZN90054.1 - 0.038 13.2 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KZN90054.1 - 0.048 13.3 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KZN90054.1 - 0.055 13.1 0.0 0.32 10.6 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 KZN90054.1 - 0.055 13.0 0.1 0.44 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 KZN90054.1 - 0.073 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KZN90054.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KZN90054.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KZN90054.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_hydro_47 PF01532.15 KZN90055.1 - 4.6e-158 526.5 0.0 5.4e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M20 PF01546.23 KZN90056.1 - 1.8e-21 76.5 0.1 2.5e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN90056.1 - 6.9e-16 57.9 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain NAD_binding_4 PF07993.7 KZN90057.1 - 3.2e-44 150.7 0.0 5.4e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN90057.1 - 5.8e-31 107.2 0.0 2.4e-30 105.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KZN90057.1 - 9.4e-13 48.1 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN90057.1 - 1.8e-05 24.8 0.0 5.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN90057.1 - 0.00037 19.2 0.0 0.024 13.3 0.0 2.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN90057.1 - 0.012 14.4 0.1 1.4 7.7 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN90057.1 - 0.16 10.8 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_42 PF02449.10 KZN90058.1 - 5.5e-111 371.2 1.6 7.5e-111 370.8 1.1 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 KZN90058.1 - 1.8e-28 99.1 0.0 2.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_14 PF01373.12 KZN90058.1 - 7.1e-06 25.0 0.1 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42C PF08533.5 KZN90058.1 - 0.00032 20.1 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain DUF4434 PF14488.1 KZN90058.1 - 0.00037 20.2 0.8 0.0067 16.1 0.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase PF00150.13 KZN90058.1 - 0.0011 18.2 0.1 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KZN90058.1 - 0.0068 15.7 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Cellulase-like PF12876.2 KZN90058.1 - 0.051 14.0 0.0 2.3 8.7 0.0 2.7 1 1 0 1 1 1 0 Sugar-binding cellulase-like PNK3P PF08645.6 KZN90060.1 - 6.8e-55 184.8 0.0 1.1e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KZN90060.1 - 8.4e-33 113.2 0.0 7.9e-32 110.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 KZN90060.1 - 2.1e-05 23.8 1.5 0.037 13.2 0.0 2.6 2 1 1 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KZN90060.1 - 0.024 13.7 0.0 0.26 10.3 0.0 2.0 1 1 0 2 2 2 0 Zeta toxin GBP_repeat PF02526.9 KZN90060.1 - 0.083 12.2 0.1 3.3 7.1 0.1 2.5 2 0 0 2 2 2 0 Glycophorin-binding protein Med18 PF09637.5 KZN90061.1 - 1.6e-64 217.8 0.0 1.8e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 KZN90062.1 - 2.9e-38 131.3 0.1 3.3e-38 131.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 KZN90063.1 - 1e-75 254.1 3.2 1.6e-75 253.5 2.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 KZN90064.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 KZN90065.1 - 1.6e-36 125.8 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90065.1 - 1.5e-14 53.7 0.0 1.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN90065.1 - 0.016 14.9 0.0 0.56 9.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtt106 PF08512.7 KZN90066.1 - 1.1e-25 89.4 0.1 4.4e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Pox_Ag35 PF03286.9 KZN90066.1 - 8.4 5.8 12.3 15 5.0 8.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KOW PF00467.24 KZN90067.1 - 0.0019 17.8 1.0 0.0037 16.9 0.7 1.5 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 KZN90068.1 - 4.4e-56 188.7 0.0 5.5e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN90068.1 - 1.5e-15 57.7 0.0 2.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN90068.1 - 3.2e-07 29.7 0.0 5.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KZN90068.1 - 0.00052 19.2 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KZN90068.1 - 0.00097 18.6 0.0 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN90068.1 - 0.0089 15.1 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1712 PF08217.6 KZN90069.1 - 8.8e-15 53.9 0.0 3.6e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 KZN90070.1 - 5.1e-21 75.0 0.1 8e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KZN90070.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain adh_short PF00106.20 KZN90071.1 - 4.8e-25 88.3 0.0 6.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN90071.1 - 1.2e-22 80.8 0.1 1.4e-22 80.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN90071.1 - 1.8e-10 40.7 0.0 4.2e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN90071.1 - 0.0011 18.4 0.0 0.0096 15.3 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribosomal_L17 PF01196.14 KZN90071.1 - 0.035 14.6 0.0 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L17 Alg14 PF08660.6 KZN90072.1 - 1.8e-53 181.0 0.3 2.9e-53 180.3 0.0 1.4 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.4 KZN90073.1 - 6.4e-39 133.4 4.0 6.4e-39 133.4 2.7 1.8 2 0 0 2 2 2 1 Ima1 N-terminal domain KduI PF04962.7 KZN90073.1 - 0.07 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 KduI/IolB family DZR PF12773.2 KZN90073.1 - 5.1 6.9 7.4 4 7.3 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF2264 PF10022.4 KZN90074.1 - 9.2e-135 448.9 0.1 1.1e-134 448.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BPL_LplA_LipB PF03099.14 KZN90075.1 - 2.5e-15 56.5 0.0 7.2e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 KZN90076.1 - 5e-131 436.3 0.0 5.7e-131 436.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase KGG PF10685.4 KZN90077.1 - 2.8e-22 78.1 19.8 6e-11 41.9 1.8 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif VanY PF02557.12 KZN90077.1 - 0.14 11.9 0.4 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Hemerythrin PF01814.18 KZN90078.1 - 5.2e-14 52.5 0.3 7.9e-14 51.9 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hairy_orange PF07527.8 KZN90078.1 - 0.017 14.8 0.1 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Hairy Orange TRF PF08558.5 KZN90078.1 - 0.065 12.5 0.3 0.13 11.6 0.1 1.5 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) CENP-O PF09496.5 KZN90078.1 - 0.11 12.6 0.2 0.21 11.8 0.1 1.5 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Zn_clus PF00172.13 KZN90080.1 - 1.9e-06 27.7 9.4 3.7e-06 26.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2146 PF10220.4 KZN90080.1 - 0.02 12.8 2.0 0.027 12.5 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) BIR PF00653.16 KZN90082.1 - 0.017 15.5 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-RING_2 PF13639.1 KZN90086.1 - 0.0007 19.3 8.4 0.0013 18.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN90086.1 - 0.0022 18.0 9.1 0.0046 16.9 6.3 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN90086.1 - 0.0095 16.0 3.2 0.024 14.7 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger DUF3330 PF11809.3 KZN90086.1 - 0.045 13.6 0.1 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN90086.1 - 0.68 10.0 7.2 1.6 8.8 5.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN90087.1 - 3.1e-26 91.5 0.9 5.6e-14 52.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90087.1 - 5.2e-22 76.5 4.9 7e-08 31.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KZN90087.1 - 2.2e-19 68.9 9.0 6.2e-07 29.4 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90087.1 - 5.5e-17 60.1 4.4 0.00023 21.1 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KZN90087.1 - 2.1e-15 56.7 5.3 2e-07 31.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN90087.1 - 9.5e-06 25.2 0.2 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN90087.1 - 2e-05 24.1 0.2 3.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain DUF4347 PF14252.1 KZN90088.1 - 0.024 14.1 0.2 0.051 13.0 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Hydrolase PF00702.21 KZN90091.1 - 2e-21 77.3 0.0 2.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN90091.1 - 2.7e-10 40.7 0.0 3.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN90091.1 - 8.8e-07 28.7 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NIF PF03031.13 KZN90091.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase ACP_syn_III_C PF08541.5 KZN90091.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3292 PF11696.3 KZN90092.1 - 7.2e-289 959.1 0.0 2.6e-240 798.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) zf-C4H2 PF10146.4 KZN90094.1 - 0.016 15.2 0.1 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein BRE1 PF08647.6 KZN90094.1 - 0.016 15.1 5.4 0.026 14.4 3.7 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TFCD_C PF12612.3 KZN90094.1 - 0.044 13.1 0.5 0.054 12.9 0.4 1.1 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Sec8_exocyst PF04048.9 KZN90094.1 - 0.22 11.1 3.5 0.61 9.7 2.4 1.7 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Phage_Mu_Gam PF07352.7 KZN90094.1 - 0.23 10.9 1.7 0.29 10.6 1.2 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein APG6 PF04111.7 KZN90094.1 - 0.36 9.8 5.6 0.38 9.7 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KZN90094.1 - 0.54 9.1 6.7 0.61 8.9 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 KZN90094.1 - 0.68 7.1 8.7 0.76 7.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 KZN90094.1 - 0.84 9.2 5.5 0.97 9.0 3.8 1.2 1 0 0 1 1 1 0 Mnd1 family Flagellar_rod PF05149.7 KZN90094.1 - 1.5 7.9 10.3 2 7.5 7.1 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein DUF4625 PF15418.1 KZN90096.1 - 0.0091 16.1 0.0 0.022 14.8 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) SirB PF04247.7 KZN90097.1 - 0.0084 15.8 0.1 0.037 13.7 0.0 1.9 2 0 0 2 2 2 1 Invasion gene expression up-regulator, SirB DUF4153 PF13687.1 KZN90097.1 - 0.022 14.2 0.1 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) Patatin PF01734.17 KZN90098.1 - 9.1e-21 74.7 1.1 1.6e-20 73.9 0.2 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN90098.1 - 0.0011 18.5 5.2 0.0045 16.6 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN90098.1 - 0.0028 17.6 8.7 0.0086 16.0 6.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN90098.1 - 0.0047 16.6 7.2 0.014 15.1 5.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN90098.1 - 0.12 12.2 9.0 0.39 10.5 6.2 2.0 1 0 0 1 1 1 0 Ring finger domain DUF2841 PF11001.3 KZN90101.1 - 2e-42 144.0 0.6 3e-42 143.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) PDGF_N PF04692.8 KZN90102.1 - 0.29 11.6 2.8 0.33 11.4 0.1 2.4 3 1 0 3 3 3 0 Platelet-derived growth factor, N terminal region Nucleo_P87 PF07267.6 KZN90102.1 - 0.67 8.5 3.4 0.92 8.1 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 OmpH PF03938.9 KZN90103.1 - 0.042 13.7 9.9 0.048 13.6 6.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.1 KZN90103.1 - 0.062 13.2 10.2 0.091 12.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DinB_2 PF12867.2 KZN90103.1 - 0.14 12.5 6.6 3.6 7.9 0.6 2.9 1 1 1 2 2 2 0 DinB superfamily APG6 PF04111.7 KZN90103.1 - 0.14 11.1 7.5 0.18 10.8 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KZN90103.1 - 0.23 11.1 10.7 3.2 7.3 0.1 1.9 1 1 1 2 2 2 0 Mnd1 family Seryl_tRNA_N PF02403.17 KZN90103.1 - 0.23 11.4 7.5 0.39 10.7 5.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 KZN90103.1 - 0.45 8.8 2.7 0.53 8.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 KZN90103.1 - 0.5 8.7 4.5 0.57 8.5 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 KZN90103.1 - 5.1 7.4 12.4 3.7 7.9 3.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Myosin_tail_1 PF01576.14 KZN90104.1 - 0.0029 15.4 0.5 0.0035 15.1 0.4 1.0 1 0 0 1 1 1 1 Myosin tail DUF972 PF06156.8 KZN90104.1 - 0.0069 16.7 0.2 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 KZN90104.1 - 0.018 14.9 1.0 0.029 14.2 0.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 KZN90104.1 - 0.023 12.7 0.1 0.026 12.5 0.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Tropomyosin_1 PF12718.2 KZN90104.1 - 0.025 14.4 0.5 0.039 13.8 0.4 1.2 1 0 0 1 1 1 0 Tropomyosin like ATG16 PF08614.6 KZN90104.1 - 0.036 13.8 0.3 0.044 13.6 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KZN90104.1 - 0.062 12.8 0.3 0.068 12.7 0.2 1.1 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 KZN90104.1 - 0.07 12.8 0.7 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_UL6 PF01763.11 KZN90104.1 - 0.11 10.6 0.2 0.15 10.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Mto2_bdg PF12808.2 KZN90104.1 - 0.27 11.3 2.5 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4200 PF13863.1 KZN90104.1 - 0.67 9.9 4.4 13 5.8 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-H2C2_2 PF13465.1 KZN90106.1 - 4.9e-19 67.6 21.3 1.6e-06 28.0 0.1 4.9 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 KZN90106.1 - 7.8e-14 51.0 37.1 0.00031 20.8 0.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN90106.1 - 0.00075 19.6 33.2 0.069 13.5 4.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN90106.1 - 0.077 13.1 6.1 17 5.6 0.1 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN90106.1 - 2.6 8.0 11.2 21 5.1 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KZN90106.1 - 7.8 6.2 15.0 2.3 8.0 2.2 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Epimerase PF01370.16 KZN90107.1 - 0.0052 16.2 0.0 0.0053 16.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KZN90107.1 - 0.0062 15.8 0.1 0.0069 15.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN90107.1 - 0.007 16.3 0.0 0.0075 16.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN90107.1 - 0.087 11.5 0.0 0.096 11.3 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family bZIP_1 PF00170.16 KZN90108.1 - 2.1e-07 30.7 13.2 3.1e-07 30.2 8.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KZN90108.1 - 0.00015 22.0 8.7 0.00015 22.0 6.0 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor dsrm PF00035.20 KZN90108.1 - 0.028 15.0 2.6 0.087 13.4 1.8 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding motif Adeno_PIX PF03955.9 KZN90108.1 - 0.19 12.2 1.2 0.32 11.5 0.9 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_2 PF07716.10 KZN90108.1 - 0.45 10.3 23.3 0.06 13.1 11.6 2.6 2 1 0 2 2 2 0 Basic region leucine zipper RRM_1 PF00076.17 KZN90109.1 - 1.8e-07 30.6 0.0 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90109.1 - 6.6e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CP2 PF04516.10 KZN90111.1 - 2e-76 256.1 0.0 3.2e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Halogen_Hydrol PF10112.4 KZN90111.1 - 0.14 11.5 0.2 0.72 9.2 0.0 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3723 PF12520.3 KZN90112.1 - 4.1e-53 180.6 0.0 5.1e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Ferritin PF00210.19 KZN90113.1 - 1e-12 48.0 0.0 1.3e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DNA_pol_alpha_N PF12254.3 KZN90114.1 - 0.061 13.1 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal bZIP_1 PF00170.16 KZN90115.1 - 5.5e-09 35.8 6.8 8.9e-09 35.1 4.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN90115.1 - 4.2e-07 29.6 7.2 7.1e-07 28.9 5.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper NUDE_C PF04880.8 KZN90115.1 - 0.03 14.6 0.5 0.043 14.1 0.4 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region bZIP_Maf PF03131.12 KZN90115.1 - 0.13 12.5 7.5 0.098 12.9 3.9 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 KZN90116.1 - 9.8e-08 31.8 6.4 1.9e-07 30.8 4.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN90116.1 - 1.8e-05 24.4 5.7 3.6e-05 23.4 4.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KZN90116.1 - 4.2 7.7 7.5 4.4 7.6 3.8 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Thioredoxin_4 PF13462.1 KZN90117.1 - 0.062 13.3 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin BRE1 PF08647.6 KZN90120.1 - 0.31 11.0 7.3 0.86 9.6 5.0 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4625 PF15418.1 KZN90122.1 - 0.00081 19.5 0.0 0.0023 18.0 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) Glyco_hydro_61 PF03443.9 KZN90122.1 - 0.067 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 FxsA PF04186.8 KZN90123.1 - 0.1 12.2 2.1 2.2 7.9 0.0 2.7 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Patatin PF01734.17 KZN90124.1 - 1.9e-21 76.9 0.8 1.1e-20 74.4 0.2 2.5 3 0 0 3 3 3 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 KZN90124.1 - 0.0039 17.1 9.9 0.013 15.5 6.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN90124.1 - 0.0057 16.3 7.4 0.017 14.8 5.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN90124.1 - 0.0066 16.0 8.4 0.024 14.2 5.8 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN90124.1 - 0.12 12.1 9.2 0.42 10.4 6.4 2.0 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 KZN90124.1 - 0.62 9.6 6.4 4.9 6.7 2.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 BAR_2 PF10455.4 KZN90126.1 - 0.025 13.5 0.1 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2706 PF10913.3 KZN90128.1 - 0.27 10.8 1.7 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) DUF3723 PF12520.3 KZN90129.1 - 1.7e-40 138.9 0.5 1.6e-20 73.1 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) DUF1129 PF06570.6 KZN90130.1 - 0.26 10.5 2.6 0.42 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Myosin_tail_1 PF01576.14 KZN90132.1 - 8.8e-05 20.4 0.4 0.00011 20.0 0.3 1.1 1 0 0 1 1 1 1 Myosin tail ATG16 PF08614.6 KZN90132.1 - 0.0016 18.3 0.6 0.0024 17.7 0.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 KZN90132.1 - 0.0017 18.7 0.2 0.0032 17.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) WEMBL PF05701.6 KZN90132.1 - 0.0018 16.8 0.5 0.0025 16.3 0.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light HALZ PF02183.13 KZN90132.1 - 0.0025 17.4 0.3 0.22 11.2 0.1 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 KZN90132.1 - 0.0047 16.7 0.8 0.0077 16.0 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 KZN90132.1 - 0.013 15.4 0.8 0.025 14.4 0.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KZN90132.1 - 0.025 14.1 0.6 0.025 14.1 0.4 1.5 2 0 0 2 2 2 0 IncA protein DUF4200 PF13863.1 KZN90132.1 - 0.028 14.3 1.1 0.028 14.3 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 KZN90132.1 - 0.051 13.6 1.0 0.11 12.5 0.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF641 PF04859.7 KZN90132.1 - 0.063 13.0 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DNA_repr_REX1B PF14966.1 KZN90132.1 - 0.087 13.2 0.1 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA repair REX1-B Herpes_UL6 PF01763.11 KZN90132.1 - 0.14 10.3 0.3 0.19 9.8 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4164 PF13747.1 KZN90132.1 - 0.21 11.7 5.0 1 9.5 3.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) LMBR1 PF04791.11 KZN90132.1 - 0.25 9.8 0.3 0.31 9.5 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mto2_bdg PF12808.2 KZN90132.1 - 0.4 10.8 0.1 0.4 10.8 0.0 3.0 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region APG6 PF04111.7 KZN90133.1 - 0.37 9.7 7.6 0.45 9.5 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 KZN90133.1 - 0.54 10.2 11.2 0.77 9.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DinB_2 PF12867.2 KZN90133.1 - 0.75 10.1 4.7 4.9 7.5 1.5 2.7 1 1 1 2 2 2 0 DinB superfamily OmpH PF03938.9 KZN90133.1 - 1.1 9.2 7.4 1.5 8.6 5.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.1 KZN90133.1 - 1.1 9.2 8.7 2.1 8.3 6.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance IncA PF04156.9 KZN90133.1 - 1.1 8.8 9.5 1.4 8.4 6.6 1.2 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 KZN90133.1 - 7.5 6.1 12.3 11 5.6 8.4 1.5 1 1 0 1 1 1 0 Mnd1 family APH PF01636.18 KZN90135.1 - 1.1e-10 41.7 0.0 4.9e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family UPF0449 PF15136.1 KZN90138.1 - 0.068 13.3 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Ank_2 PF12796.2 KZN90139.1 - 2.3e-31 107.9 1.1 6.1e-17 61.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN90139.1 - 1.5e-18 66.7 1.2 1.7e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN90139.1 - 1.8e-16 59.0 1.1 1.2e-08 34.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN90139.1 - 5.7e-16 58.1 1.5 4.4e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90139.1 - 1.6e-13 49.4 0.6 2.2e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KZN90140.1 - 8.3e-17 61.2 0.2 4.5e-06 27.0 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN90140.1 - 3.6e-16 59.2 0.0 6.7e-09 35.9 0.0 3.1 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN90140.1 - 1.1e-12 47.7 0.0 9.7e-05 22.4 0.0 4.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN90140.1 - 2e-12 46.2 0.0 0.0033 17.1 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KZN90140.1 - 1.6e-06 27.7 0.0 2.5 8.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Zn_clus PF00172.13 KZN90141.1 - 4.5e-09 36.0 12.3 8.9e-09 35.1 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN90141.1 - 0.00031 19.6 0.0 0.00081 18.3 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRN7 PF11781.3 KZN90141.1 - 0.76 9.3 7.6 1.5 8.3 5.3 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Dimer_Tnp_hAT PF05699.9 KZN90142.1 - 3.5e-07 29.7 0.0 9.8e-07 28.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KZN90142.1 - 1.5e-05 24.8 0.3 0.0002 21.2 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4413) Methyltransf_23 PF13489.1 KZN90144.1 - 5.2e-08 32.7 0.0 9.6e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90144.1 - 0.00027 20.5 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90144.1 - 0.00074 19.9 0.0 0.0014 19.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN90144.1 - 0.00089 19.6 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ras PF00071.17 KZN90145.1 - 1e-37 128.9 0.0 2.6e-37 127.7 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN90145.1 - 2.5e-12 47.3 0.0 5.9e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN90145.1 - 0.00019 21.3 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-CCHC PF00098.18 KZN90146.1 - 0.0022 17.8 4.7 0.0046 16.8 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 KZN90148.1 - 7.3e-10 38.0 0.1 1.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KZN90148.1 - 0.037 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Zn_clus PF00172.13 KZN90151.1 - 5.2e-08 32.6 10.3 1.1e-07 31.5 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.3 KZN90152.1 - 3.9e-40 136.6 0.9 6.3e-40 135.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF1349 PF07081.6 KZN90152.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Cyclin PF08613.6 KZN90153.1 - 1.5e-12 48.1 0.0 2.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN90153.1 - 6.3e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Hydrolase PF00702.21 KZN90154.1 - 1.1e-15 58.6 0.0 1.2e-14 55.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KZN90154.1 - 4e-14 52.2 0.5 6.1e-14 51.6 0.4 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN90154.1 - 6.1e-10 38.9 0.3 6.1e-10 38.9 0.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KZN90154.1 - 2.1e-07 30.7 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN90154.1 - 6.1e-06 26.5 0.0 1.5e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN90154.1 - 0.083 12.4 0.5 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Chibby PF14645.1 KZN90156.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Chibby family HSF_DNA-bind PF00447.12 KZN90159.1 - 8.6e-11 41.9 0.1 3.1e-10 40.1 0.1 1.9 1 1 0 1 1 1 1 HSF-type DNA-binding zf-H2C2_2 PF13465.1 KZN90160.1 - 0.00088 19.4 6.7 0.001 19.2 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN90160.1 - 0.0011 19.1 4.9 0.5 10.8 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN90160.1 - 0.0013 18.9 7.3 0.15 12.4 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type RNA_pol_I_TF PF04090.7 KZN90160.1 - 0.046 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Methyltransf_23 PF13489.1 KZN90161.1 - 6.4e-15 55.2 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN90161.1 - 5.9e-08 33.2 0.0 3.4e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90161.1 - 0.0018 17.8 0.0 0.0062 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN90161.1 - 0.0019 17.2 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 KZN90161.1 - 0.007 16.8 0.0 0.12 12.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90161.1 - 0.013 15.9 0.0 0.07 13.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KZN90161.1 - 0.056 13.4 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KZN90161.1 - 0.1 11.7 0.0 6 5.9 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KZN90161.1 - 0.12 11.4 0.0 3.6 6.6 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KZN90161.1 - 0.13 11.5 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain DUF4219 PF13961.1 KZN90163.1 - 3.5e-09 35.8 0.5 7.2e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KZN90163.1 - 2.4e-06 27.1 0.0 0.0091 15.5 0.0 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KZN90163.1 - 3.3e-06 26.8 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KZN90163.1 - 0.00065 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KZN90163.1 - 0.14 12.1 0.4 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Molybdopterin PF00384.17 KZN90164.1 - 3.1e-64 217.2 0.0 4.5e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 KZN90164.1 - 1.9e-29 101.6 0.0 4.2e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 KZN90164.1 - 2.1e-12 46.6 1.6 2.9e-12 46.2 0.4 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain DUF3431 PF11913.3 KZN90165.1 - 3.7e-25 88.7 0.0 4.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Caleosin PF05042.8 KZN90167.1 - 1.4e-55 187.5 0.0 1.8e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.27 KZN90167.1 - 4.2e-05 22.5 4.8 0.00041 19.4 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 KZN90167.1 - 5.4e-05 22.7 6.9 0.00017 21.1 0.1 3.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KZN90167.1 - 9.4e-05 22.4 0.1 0.001 19.1 0.1 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KZN90167.1 - 0.0055 16.2 0.3 0.099 12.2 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KZN90167.1 - 0.015 14.5 10.0 0.017 14.4 0.3 3.6 4 0 0 4 4 4 0 EF hand NmrA PF05368.8 KZN90169.1 - 1.3e-26 93.3 0.0 2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN90169.1 - 8.6e-11 42.1 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KZN90169.1 - 3e-05 24.3 0.1 5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KZN90169.1 - 0.0016 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KZN90169.1 - 0.0033 16.1 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KZN90169.1 - 0.0048 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KZN90169.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 KZN90169.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 KZN90169.1 - 0.077 13.5 0.1 0.44 11.0 0.0 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ank_2 PF12796.2 KZN90170.1 - 1.5e-35 121.4 7.6 3.4e-16 59.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90170.1 - 1.6e-31 106.5 14.4 3.1e-06 26.7 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KZN90170.1 - 1.8e-30 104.7 7.5 4.5e-09 36.5 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN90170.1 - 1.2e-28 98.5 9.9 6.6e-08 32.5 0.0 6.1 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90170.1 - 2.4e-25 86.0 5.8 8.3e-05 22.4 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat E3_binding PF02817.12 KZN90170.1 - 0.15 11.7 0.1 19 5.0 0.0 2.8 3 0 0 3 3 3 0 e3 binding domain HeLo PF14479.1 KZN90171.1 - 9e-40 136.6 0.0 1.5e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KZN90171.1 - 0.00027 20.1 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Transferase PF02458.10 KZN90173.1 - 1.3e-19 69.9 0.0 1.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Transferase family DUF3505 PF12013.3 KZN90174.1 - 7.9e-08 32.5 0.2 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) APH PF01636.18 KZN90176.1 - 6.9e-11 42.3 0.1 6.8e-10 39.0 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN90176.1 - 8.8e-11 41.7 0.0 2.1e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Glyco_hydro_31 PF01055.21 KZN90177.1 - 3.9e-128 428.0 2.6 4.7e-128 427.7 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN90177.1 - 0.00024 20.9 2.5 0.0082 15.9 0.1 3.3 3 1 0 3 3 3 1 Galactose mutarotase-like APH PF01636.18 KZN90178.1 - 4.6e-14 52.7 0.0 7.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN90178.1 - 0.0064 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN90178.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2414 PF10309.4 KZN90179.1 - 3.8e-22 77.7 0.0 5.9e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF4610 PF15384.1 KZN90179.1 - 0.0081 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4610) LisH PF08513.6 KZN90180.1 - 0.00047 19.8 0.1 0.00099 18.7 0.0 1.6 1 0 0 1 1 1 1 LisH WD40 PF00400.27 KZN90180.1 - 0.0024 17.6 1.9 5.7 6.9 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribosomal_L29e PF01779.12 KZN90181.1 - 2.7e-21 75.1 9.7 2.7e-21 75.1 6.7 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.11 KZN90182.1 - 3e-20 71.7 0.1 4.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.11 KZN90184.1 - 0.0006 19.6 10.3 0.0028 17.4 6.7 2.2 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KZN90184.1 - 1.2 8.7 5.2 3.9 7.0 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) PQ-loop PF04193.9 KZN90185.1 - 4.5e-33 112.5 13.7 8e-18 63.7 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat zf-C2H2_4 PF13894.1 KZN90186.1 - 1.8e-05 24.7 12.1 0.38 11.2 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger Serglycin PF04360.7 KZN90186.1 - 0.072 12.8 0.5 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Serglycin zf-C2H2 PF00096.21 KZN90186.1 - 0.18 12.2 8.2 0.19 12.1 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Abhydrolase_6 PF12697.2 KZN90187.1 - 6.7e-05 22.8 0.0 8.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN90187.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KZN90187.1 - 0.00096 18.5 0.0 0.0029 16.9 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KZN90187.1 - 0.0099 15.6 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-C2H2 PF00096.21 KZN90188.1 - 1.2e-06 28.5 12.9 0.0052 17.0 1.2 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN90188.1 - 7.8e-06 25.8 15.7 0.00064 19.8 2.0 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN90188.1 - 0.00099 19.2 14.0 0.41 11.0 0.1 4.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-Di19 PF05605.7 KZN90188.1 - 0.42 10.7 6.9 0.18 11.9 0.7 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.18 KZN90189.1 - 2.3e-39 135.5 0.0 3.9e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KZN90189.1 - 1.3e-05 24.4 0.0 4.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KZN90189.1 - 0.0013 18.0 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KZN90189.1 - 0.0028 17.2 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KZN90189.1 - 0.0077 15.3 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 KZN90189.1 - 0.041 12.8 0.0 0.99 8.3 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase dUTPase PF00692.14 KZN90190.1 - 4.7e-43 145.7 0.0 6e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KZN90190.1 - 0.064 11.6 0.0 0.089 11.1 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.7 KZN90191.1 - 5.2e-13 48.7 0.0 1.5e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KZN90191.1 - 4.3e-07 29.3 1.3 7e-06 25.3 0.0 2.7 2 1 0 2 2 2 1 pfkB family carbohydrate kinase StbA PF06406.6 KZN90191.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 StbA protein Afi1 PF07792.7 KZN90193.1 - 2.5e-63 212.4 0.0 4.3e-63 211.6 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KZN90193.1 - 1.1e-38 131.3 0.0 1.9e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KZN90193.1 - 6.7e-10 37.9 0.0 0.003 16.1 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 KZN90193.1 - 0.025 13.8 0.0 0.075 12.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) CD99L2 PF12301.3 KZN90193.1 - 0.065 12.9 2.8 0.11 12.1 1.9 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 HEAT PF02985.17 KZN90193.1 - 0.1 12.7 0.0 0.47 10.6 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat EF-hand_6 PF13405.1 KZN90194.1 - 7.2e-12 44.1 6.1 6.9e-06 25.5 0.1 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KZN90194.1 - 3.5e-11 41.5 3.6 7.9e-06 24.8 0.2 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KZN90194.1 - 1.6e-10 40.9 0.3 2.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KZN90194.1 - 1.8e-06 27.0 7.4 0.0061 15.8 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KZN90194.1 - 2.7e-06 26.8 2.2 0.012 15.2 0.2 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 KZN90194.1 - 0.014 15.3 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.13 KZN90195.1 - 5.5e-29 101.1 0.0 3.8e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain p450 PF00067.17 KZN90196.1 - 0.00022 19.9 1.2 0.00039 19.0 0.3 1.8 2 1 0 2 2 2 1 Cytochrome P450 RRM_1 PF00076.17 KZN90197.1 - 9.4e-13 47.6 0.0 5.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90197.1 - 5.8e-10 39.0 0.0 3.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90197.1 - 2.9e-06 27.0 0.0 8.5e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glucosamine_iso PF01182.15 KZN90198.1 - 6.2e-58 195.8 0.0 7.5e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Thionin PF00321.12 KZN90199.1 - 0.00086 19.4 1.6 0.0011 19.1 1.1 1.1 1 0 0 1 1 1 1 Plant thionin Hom_end PF05204.9 KZN90199.1 - 0.0071 16.2 0.1 0.0077 16.1 0.0 1.0 1 0 0 1 1 1 1 Homing endonuclease Toxin_7 PF05980.7 KZN90200.1 - 1.6 8.8 9.6 9 6.4 6.7 2.0 1 1 0 1 1 1 0 Toxin 7 Conotoxin PF02950.12 KZN90200.1 - 1.9 9.3 14.5 0.32 11.8 5.5 2.0 1 1 1 2 2 2 0 Conotoxin Toxin_12 PF07740.7 KZN90200.1 - 9.1 6.8 10.2 29 5.2 7.1 1.8 1 1 0 1 1 1 0 Ion channel inhibitory toxin WD40 PF00400.27 KZN90201.1 - 1.4e-17 62.8 9.4 6.7e-08 32.1 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 KZN90202.1 - 1.5e-24 84.8 14.0 2.5e-08 33.4 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF4463 PF14703.1 KZN90202.1 - 0.73 10.3 3.2 3.1 8.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) SET PF00856.23 KZN90203.1 - 8.9e-08 32.6 0.7 0.00078 19.7 0.1 3.1 4 0 0 4 4 4 2 SET domain TPR_9 PF13371.1 KZN90203.1 - 0.062 13.1 0.5 0.23 11.3 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-MYND PF01753.13 KZN90203.1 - 0.083 12.7 3.7 0.21 11.4 2.5 1.8 1 0 0 1 1 1 0 MYND finger MA3 PF02847.12 KZN90204.1 - 8.3e-27 93.1 0.1 3.1e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KZN90204.1 - 4e-24 85.1 0.6 7e-24 84.4 0.4 1.4 1 0 0 1 1 1 1 MIF4G domain DPM2 PF07297.7 KZN90205.1 - 3.6e-33 113.6 1.6 4.3e-33 113.4 1.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KZN90205.1 - 6.9e-05 22.4 0.7 8.3e-05 22.2 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4083 PF13314.1 KZN90205.1 - 0.0006 19.5 0.1 0.0006 19.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) DUF1469 PF07332.6 KZN90205.1 - 0.051 13.2 1.4 0.065 12.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Cation_efflux PF01545.16 KZN90205.1 - 0.057 12.4 0.2 0.065 12.2 0.2 1.0 1 0 0 1 1 1 0 Cation efflux family EamA PF00892.15 KZN90205.1 - 0.2 11.6 3.5 0.53 10.3 2.4 1.6 1 1 0 1 1 1 0 EamA-like transporter family HAMP PF00672.20 KZN90205.1 - 0.36 11.0 2.7 6.9 6.9 0.4 2.1 2 0 0 2 2 2 0 HAMP domain DUF4229 PF14012.1 KZN90205.1 - 0.75 9.7 4.1 0.94 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF3169 PF11368.3 KZN90205.1 - 1.2 8.3 3.7 3.4 6.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) FixQ PF05545.6 KZN90205.1 - 2.6 7.7 5.4 20 4.9 2.3 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Helicase_C PF00271.26 KZN90207.1 - 1e-19 70.1 0.2 4.2e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN90207.1 - 1.2e-19 70.4 0.0 5e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KZN90207.1 - 1.1e-18 67.7 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KZN90207.1 - 0.049 12.5 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KZN90207.1 - 0.053 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 KZN90208.1 - 1.6 6.9 13.0 1.8 6.7 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1180 PF06679.7 KZN90208.1 - 5.2 6.9 6.8 0.28 11.0 0.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Presenilin PF01080.12 KZN90208.1 - 8 5.1 6.0 9.6 4.9 4.2 1.2 1 0 0 1 1 1 0 Presenilin Golgin_A5 PF09787.4 KZN90208.1 - 9 4.6 6.3 10 4.5 4.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HD PF01966.17 KZN90209.1 - 9.8e-05 22.3 0.5 0.00032 20.6 0.2 2.0 2 1 0 2 2 2 1 HD domain F_actin_cap_B PF01115.12 KZN90210.1 - 1.1e-107 358.7 0.0 1.3e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 KZN90211.1 - 2.9e-33 114.3 0.0 3.8e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF1385 PF07136.6 KZN90211.1 - 0.13 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) WD40 PF00400.27 KZN90212.1 - 3.3e-51 169.4 23.6 4.8e-10 38.9 0.7 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KZN90212.1 - 2.4e-47 160.6 0.0 3.7e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KZN90212.1 - 5.8e-07 28.0 5.7 0.0013 16.9 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.6 KZN90212.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 LisH Nbas_N PF15492.1 KZN90212.1 - 0.0073 15.4 0.5 0.63 9.0 0.2 3.0 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 KZN90212.1 - 0.0082 15.8 0.4 0.047 13.3 0.1 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KZN90212.1 - 0.0085 14.8 0.3 2.6 6.6 0.0 3.5 2 1 1 3 3 3 1 Nup133 N terminal like DUF4106 PF13388.1 KZN90212.1 - 0.11 11.4 6.8 0.27 10.1 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Abhydrolase_6 PF12697.2 KZN90213.1 - 3.4e-22 79.4 0.2 5.6e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN90213.1 - 2.3e-08 33.8 0.0 5.6e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90213.1 - 1.5e-05 24.6 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 KZN90213.1 - 0.046 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RNase_T PF00929.19 KZN90214.1 - 5e-06 26.8 0.0 0.019 15.2 0.0 2.2 1 1 1 2 2 2 2 Exonuclease Cwf_Cwc_15 PF04889.7 KZN90215.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Aldedh PF00171.17 KZN90216.1 - 9e-146 485.8 0.0 1.1e-145 485.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN90216.1 - 2.8e-07 29.6 0.0 4.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KZN90216.1 - 0.0006 19.1 0.0 0.021 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) Matrilin_ccoil PF10393.4 KZN90216.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2417 PF10329.4 KZN90217.1 - 8.2e-84 280.6 0.1 1e-83 280.2 0.1 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KZN90217.1 - 1.1e-08 35.3 1.2 2.2e-08 34.2 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2975 PF11188.3 KZN90217.1 - 6.9 6.3 14.6 1 9.0 3.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) NPL4 PF05021.10 KZN90218.1 - 4.8e-125 416.7 0.0 5.9e-125 416.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KZN90218.1 - 6.4e-71 236.7 0.1 1e-70 236.1 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KZN90218.1 - 2.6e-05 24.4 0.1 0.00061 20.0 0.0 2.9 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 Flavodoxin_1 PF00258.20 KZN90219.1 - 5.9e-10 39.3 0.1 8.6e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KZN90219.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KZN90219.1 - 3.6e-07 29.8 0.0 4.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 KZN90219.1 - 0.0095 15.9 0.0 0.035 14.1 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin domain zf-CCCH PF00642.19 KZN90220.1 - 4.4e-19 67.7 29.7 1.7e-06 27.5 0.8 5.2 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KZN90220.1 - 0.1 12.0 3.9 0.66 9.5 0.1 3.0 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 KZN90220.1 - 0.39 10.7 0.1 0.39 10.7 0.1 5.0 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Epimerase PF01370.16 KZN90221.1 - 4.3e-18 65.6 0.0 6.6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN90221.1 - 5.3e-14 51.5 0.0 3.7e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN90221.1 - 2.9e-13 50.2 0.5 1e-12 48.4 0.2 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KZN90221.1 - 1.5e-07 30.9 0.0 9.7e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 KZN90221.1 - 4.6e-07 29.9 0.1 1.3e-06 28.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KZN90221.1 - 4.8e-06 25.6 0.2 0.00024 20.1 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KZN90221.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tautomerase_3 PF14832.1 KZN90222.1 - 2.7e-51 173.1 0.1 3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 KZN90222.1 - 0.049 13.2 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme NACHT PF05729.7 KZN90223.1 - 4e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN90223.1 - 6.7e-08 32.7 0.1 8.5e-06 25.8 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 KZN90223.1 - 0.00042 19.9 3.6 0.68 9.6 0.1 3.0 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KZN90223.1 - 0.0014 18.4 1.0 1.6 8.8 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN90223.1 - 0.003 17.6 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_19 PF13245.1 KZN90223.1 - 0.0046 16.6 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KZN90223.1 - 0.0082 16.2 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 KZN90223.1 - 0.027 14.4 4.5 0.047 13.6 1.3 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.17 KZN90223.1 - 0.031 14.4 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 KZN90223.1 - 0.076 13.8 0.0 2 9.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KZN90223.1 - 0.095 12.4 0.0 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TPR_16 PF13432.1 KZN90223.1 - 3.9 8.2 11.3 0.57 10.9 1.2 4.2 5 0 0 5 5 3 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.23 KZN90224.1 - 1.6e-79 267.8 0.0 1.8e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KZN90224.1 - 5.6e-06 26.1 0.0 8.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Acyl-CoA_dh_1 PF00441.19 KZN90225.1 - 5.3e-18 65.5 0.1 2.4e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN90225.1 - 4.4e-06 26.1 0.1 7e-05 22.2 0.1 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fungal_trans PF04082.13 KZN90227.1 - 2.8e-12 46.0 0.0 5.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90227.1 - 2.3e-09 36.9 13.1 4.4e-09 36.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 KZN90228.1 - 1.4e-39 135.6 0.0 2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KZN90228.1 - 0.053 13.2 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 PIG-F PF06699.6 KZN90229.1 - 2.2e-51 174.5 4.1 3.1e-51 174.0 2.9 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4310 PF14187.1 KZN90229.1 - 0.018 14.5 0.1 0.04 13.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4310) Gly-zipper_YMGG PF13441.1 KZN90229.1 - 0.021 14.3 0.6 0.055 12.9 0.0 2.0 2 1 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 KZN90229.1 - 0.11 12.2 4.3 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycine zipper DUF3169 PF11368.3 KZN90229.1 - 0.11 11.6 0.0 0.73 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Rick_17kDa_Anti PF05433.10 KZN90229.1 - 2 8.1 0.0 2 8.1 0.0 2.6 3 0 0 3 3 3 0 Glycine zipper 2TM domain RhoGAP PF00620.22 KZN90230.1 - 5.5e-37 126.7 0.0 9e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.10 KZN90231.1 - 1.4e-19 69.0 7.2 1.9e-19 68.7 5.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KZN90231.1 - 0.043 13.2 5.8 0.069 12.6 4.0 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) GED PF02212.13 KZN90231.1 - 0.047 13.5 0.6 0.059 13.2 0.4 1.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain PALP PF00291.20 KZN90232.1 - 1.7e-31 109.6 0.0 2.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 KZN90232.1 - 0.053 12.4 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 LytB protein NAD_binding_5 PF07994.7 KZN90233.1 - 1.5e-110 369.3 0.1 1.8e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KZN90233.1 - 2.6e-46 156.0 0.6 5.6e-46 154.9 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF1459 PF07312.6 KZN90233.1 - 0.14 12.1 0.1 0.67 9.9 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1459) Sugar_tr PF00083.19 KZN90234.1 - 5.5e-81 272.4 26.5 6.2e-81 272.2 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN90234.1 - 7e-21 74.3 33.0 7e-21 74.3 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydr_30_2 PF14587.1 KZN90234.1 - 0.23 10.3 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Fungal_trans_2 PF11951.3 KZN90235.1 - 5e-09 35.2 0.0 7.7e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LIM PF00412.17 KZN90236.1 - 4.4e-16 58.6 23.9 8.8e-11 41.7 3.1 3.1 3 0 0 3 3 3 2 LIM domain Terminase_GpA PF05876.7 KZN90236.1 - 0.0015 17.0 0.7 0.0024 16.2 0.5 1.3 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) GDPD PF03009.12 KZN90237.1 - 2.8e-32 112.2 0.0 5.7e-32 111.2 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ADH_zinc_N PF00107.21 KZN90239.1 - 8e-26 90.1 0.1 1.1e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN90239.1 - 1e-18 68.4 0.0 2.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN90239.1 - 2.5e-11 43.2 0.1 5.2e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.6 KZN90240.1 - 2.5e-07 30.0 0.0 5.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KZN90240.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 KZN90240.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SopA PF13981.1 KZN90241.1 - 0.0016 18.4 0.1 0.0037 17.2 0.1 1.6 1 1 0 1 1 1 1 SopA-like central domain Sulfotransfer_1 PF00685.22 KZN90241.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.8 1 1 0 1 1 1 0 Sulfotransferase domain MFS_1 PF07690.11 KZN90242.1 - 1.8e-33 115.7 28.9 1.8e-33 115.7 20.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.1 KZN90243.1 - 1.1e-18 68.0 0.2 1.6e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN90243.1 - 5.5e-14 52.5 0.1 1.7e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NUP PF06516.6 KZN90244.1 - 2.6e-129 430.5 0.1 3e-129 430.3 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ank_2 PF12796.2 KZN90245.1 - 4.2e-191 619.9 58.8 1.5e-17 63.6 0.1 14.5 4 3 13 18 18 18 18 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90245.1 - 1.4e-124 400.2 82.5 4.3e-06 26.2 0.0 33.4 33 0 0 33 33 33 29 Ankyrin repeat Ank_4 PF13637.1 KZN90245.1 - 3.2e-101 330.1 35.2 4.2e-08 33.4 0.2 23.8 9 5 12 24 24 24 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90245.1 - 2.7e-89 284.0 43.6 0.0016 18.4 0.0 31.9 33 0 0 33 33 33 20 Ankyrin repeat Ank_5 PF13857.1 KZN90245.1 - 1.6e-79 260.1 55.2 1.9e-07 31.0 0.6 23.4 12 5 11 23 23 23 20 Ankyrin repeats (many copies) NACHT PF05729.7 KZN90245.1 - 2.3e-05 24.0 0.0 6.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KZN90245.1 - 0.00013 22.0 0.0 0.00042 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KZN90245.1 - 0.028 13.2 0.0 0.064 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF4440 PF14534.1 KZN90246.1 - 1.7e-07 31.3 0.0 2e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KZN90246.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 KZN90247.1 - 2e-38 132.0 34.1 1.7e-33 115.8 18.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN90247.1 - 0.012 15.4 0.2 0.33 10.7 0.0 2.8 2 0 0 2 2 2 0 MFS_1 like family Oleosin PF01277.12 KZN90247.1 - 1.5 8.4 9.1 0.2 11.2 2.1 2.7 2 0 0 2 2 2 0 Oleosin LacY_symp PF01306.14 KZN90247.1 - 4.1 5.8 15.4 3.1 6.2 0.1 3.0 3 1 0 3 3 3 0 LacY proton/sugar symporter DUF2955 PF11168.3 KZN90247.1 - 7.4 6.2 19.4 0.042 13.5 3.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2955) FAD_binding_3 PF01494.14 KZN90248.1 - 1.9e-13 50.2 0.1 1.5e-12 47.2 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN90248.1 - 3.3e-09 36.1 0.1 9.5e-06 24.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN90248.1 - 1e-05 25.4 0.0 2.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN90248.1 - 0.00048 19.9 0.3 0.0072 16.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KZN90248.1 - 0.015 13.9 2.5 0.22 10.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KZN90248.1 - 0.016 15.1 0.1 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN90248.1 - 0.017 13.9 0.3 0.037 12.8 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KZN90248.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 KZN90248.1 - 0.083 11.9 0.1 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pec_lyase_C PF00544.14 KZN90249.1 - 7.3e-43 146.3 9.3 1e-42 145.8 6.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KZN90249.1 - 1.9e-05 24.4 13.3 0.001 18.8 8.9 2.4 1 1 0 1 1 1 1 Right handed beta helix region DIOX_N PF14226.1 KZN90250.1 - 1.4e-23 83.6 0.0 3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN90250.1 - 1.2e-18 67.2 0.0 3.1e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EcsB PF05975.7 KZN90250.1 - 0.2 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB FAD_binding_4 PF01565.18 KZN90251.1 - 4.4e-31 107.2 7.5 6.9e-31 106.5 5.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN90251.1 - 6.7e-13 48.3 0.2 1.3e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.9 KZN90251.1 - 0.046 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase COG4 PF08318.7 KZN90251.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 COG4 transport protein Aldedh PF00171.17 KZN90252.1 - 3.1e-139 464.2 0.5 3.5e-139 464.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN90252.1 - 0.0002 20.2 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1275 PF06912.6 KZN90253.1 - 7.7e-41 139.5 11.3 9.4e-41 139.3 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3353 PF11833.3 KZN90253.1 - 2.9 7.2 8.1 1.5 8.2 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Pcc1 PF09341.5 KZN90254.1 - 4.1e-26 90.8 0.4 1.4e-25 89.1 0.3 1.7 1 1 0 1 1 1 1 Transcription factor Pcc1 DUF4571 PF15137.1 KZN90254.1 - 0.0069 15.8 0.0 0.0084 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) PEP_mutase PF13714.1 KZN90255.1 - 3.2e-44 150.9 0.0 3.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KZN90255.1 - 1.3e-22 79.7 0.1 1.9e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family CCDC92 PF14916.1 KZN90256.1 - 0.031 13.8 1.3 0.2 11.3 0.8 2.2 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DivIVA PF05103.8 KZN90256.1 - 0.076 13.0 4.7 2.5 8.1 0.4 2.3 2 0 0 2 2 2 0 DivIVA protein Apt1 PF10351.4 KZN90256.1 - 0.11 11.3 1.5 0.17 10.6 1.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain HSP70 PF00012.15 KZN90257.1 - 0.00017 19.6 0.1 0.0015 16.5 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein Glyco_hydro_20 PF00728.17 KZN90258.1 - 1e-34 120.3 2.2 5.1e-34 117.9 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KZN90258.1 - 4.3e-08 33.7 0.0 1.2e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Fungal_trans PF04082.13 KZN90259.1 - 6e-20 71.2 0.1 1e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90259.1 - 7.5e-06 25.7 9.6 1.5e-05 24.8 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2655 PF10848.3 KZN90259.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) AMP-binding PF00501.23 KZN90261.1 - 2.3e-84 283.2 0.0 2.9e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN90261.1 - 2.3e-11 44.4 0.1 5.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1275 PF06912.6 KZN90262.1 - 2.6e-41 141.1 11.1 3.3e-41 140.7 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4603 PF15376.1 KZN90262.1 - 0.11 9.6 0.1 0.14 9.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4131 PF13567.1 KZN90262.1 - 0.57 9.5 7.6 5.8 6.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Transgly_assoc PF04226.8 KZN90262.1 - 4.4 7.4 8.3 6.4 6.9 2.0 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein FA_desaturase PF00487.19 KZN90263.1 - 1.9e-31 109.4 23.3 2.7e-31 108.9 16.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PTR2 PF00854.16 KZN90264.1 - 2.9e-34 118.4 9.0 4.4e-34 117.8 6.2 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 KZN90264.1 - 4.2e-10 38.8 23.6 2.2e-09 36.5 16.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily CcmH PF03918.9 KZN90264.1 - 0.049 12.6 0.1 1.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF1469 PF07332.6 KZN90264.1 - 0.1 12.3 15.6 0.16 11.6 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) DUF443 PF04276.7 KZN90264.1 - 2.7 7.3 7.2 0.33 10.3 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Acetyltransf_3 PF13302.1 KZN90265.1 - 1.5e-17 64.0 0.0 2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN90265.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KZN90265.1 - 7.3e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN90265.1 - 0.0016 18.3 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN90265.1 - 0.0064 16.2 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KZN90265.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1581 PF07619.6 KZN90265.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) FMO-like PF00743.14 KZN90266.1 - 6.7e-28 97.1 0.0 5.3e-10 38.1 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN90266.1 - 5.3e-19 69.0 0.0 1.2e-17 64.6 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN90266.1 - 3.1e-09 36.8 0.1 2.2e-07 30.7 0.2 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN90266.1 - 6.4e-08 31.9 0.1 0.00015 20.7 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN90266.1 - 7e-08 32.5 0.0 0.0039 17.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN90266.1 - 8.3e-07 28.9 0.0 2.7e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN90266.1 - 0.0017 17.4 0.1 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KZN90266.1 - 0.0056 15.6 0.0 4.3 6.1 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN90266.1 - 0.0079 16.5 1.0 2.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN90266.1 - 0.071 12.1 0.0 0.15 11.0 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase His_Phos_1 PF00300.17 KZN90267.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.19 KZN90268.1 - 4.4e-106 355.1 19.1 6e-106 354.7 13.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN90268.1 - 4.9e-21 74.8 24.1 4.9e-21 74.8 16.7 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily TMEM151 PF14857.1 KZN90268.1 - 0.029 12.9 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 TMEM151 family F-box-like PF12937.2 KZN90270.1 - 0.00032 20.3 0.1 0.00075 19.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.3 KZN90270.1 - 0.019 14.8 1.0 0.086 12.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) IucA_IucC PF04183.7 KZN90270.1 - 0.049 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 IucA / IucC family Redoxin PF08534.5 KZN90271.1 - 4e-38 130.2 0.0 4.4e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KZN90271.1 - 1.3e-14 53.9 0.0 1.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AP_endonuc_2 PF01261.19 KZN90272.1 - 4e-10 39.3 0.0 5.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FAD_binding_2 PF00890.19 KZN90274.1 - 1.3e-37 129.7 1.5 3e-36 125.1 1.1 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN90274.1 - 3.7e-12 45.8 0.4 2.7e-09 36.3 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN90274.1 - 8.3e-11 41.6 0.4 1.6e-10 40.6 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN90274.1 - 5.1e-08 32.8 1.6 2.5e-07 30.6 1.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN90274.1 - 1.8e-07 30.4 0.7 8e-07 28.3 0.5 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KZN90274.1 - 4e-06 25.5 0.5 1e-05 24.2 0.4 1.9 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KZN90274.1 - 3.5e-05 23.9 0.1 0.00039 20.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN90274.1 - 4.5e-05 23.4 2.9 0.00024 21.0 2.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN90274.1 - 0.00064 18.8 0.6 0.0011 18.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN90274.1 - 0.0024 18.2 1.3 0.0046 17.3 0.4 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN90274.1 - 0.006 15.4 2.9 0.006 15.4 2.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN90274.1 - 0.036 12.9 0.2 0.058 12.2 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KZN90274.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KZN90274.1 - 0.47 10.0 1.9 0.78 9.3 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.7 KZN90275.1 - 6.8e-22 77.2 1.4 1.2e-21 76.4 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN90275.1 - 1.2e-15 57.1 0.0 2.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN90275.1 - 9.2e-05 21.6 0.2 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KZN90275.1 - 0.0013 18.3 0.3 0.0024 17.4 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KZN90275.1 - 0.0094 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KZN90275.1 - 0.021 14.6 0.1 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KZN90275.1 - 0.039 13.6 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KZN90275.1 - 0.042 13.6 0.5 0.068 13.0 0.3 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KZN90275.1 - 0.047 13.1 0.1 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MAF_flag10 PF01973.13 KZN90275.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 DUF1075 PF06388.6 KZN90276.1 - 0.15 11.7 0.6 0.33 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Pyr_redox_3 PF13738.1 KZN90277.1 - 7.4e-19 68.6 0.0 2.2e-18 67.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN90277.1 - 4e-12 45.1 0.0 2.9e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KZN90277.1 - 4.5e-08 33.2 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN90277.1 - 1.9e-07 30.9 0.1 6.4e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN90277.1 - 3e-07 29.6 0.0 5.5e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN90277.1 - 7.3e-05 22.5 0.3 0.0016 18.2 0.1 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KZN90277.1 - 0.00054 19.1 1.1 0.0019 17.3 0.7 2.0 1 1 0 1 1 1 1 Thi4 family DAO PF01266.19 KZN90277.1 - 0.0015 17.4 0.1 0.035 13.0 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN90277.1 - 0.004 16.1 0.0 0.0088 15.0 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN90277.1 - 0.0049 15.4 0.2 0.39 9.1 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein zf-HC2 PF13490.1 KZN90277.1 - 0.065 13.1 0.2 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Putative zinc-finger FAD_binding_2 PF00890.19 KZN90277.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KZN90277.1 - 0.12 12.7 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CrtC PF07143.6 KZN90278.1 - 1.1e-16 60.9 0.4 1.8e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-C2H2 PF00096.21 KZN90279.1 - 5.6e-11 42.1 13.1 1.1e-05 25.4 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN90279.1 - 2.3e-09 36.9 8.0 4.8e-05 23.3 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN90279.1 - 4.6e-09 36.1 9.1 8e-07 29.0 1.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 KZN90279.1 - 0.00027 20.9 7.9 0.019 15.1 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KZN90279.1 - 0.00046 20.2 3.0 0.014 15.5 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KZN90279.1 - 0.012 15.4 4.3 0.42 10.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KZN90279.1 - 0.051 13.3 1.3 0.22 11.2 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger zf-CHY PF05495.7 KZN90279.1 - 0.095 12.8 0.9 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 KZN90279.1 - 0.21 11.8 0.2 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DLH PF01738.13 KZN90280.1 - 1.2e-13 50.8 0.0 1.6e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KZN90280.1 - 0.0017 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90280.1 - 0.0048 16.4 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.13 KZN90282.1 - 3e-08 33.4 6.3 4.4e-08 32.9 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AreA_N PF07573.6 KZN90283.1 - 3.8e-23 81.8 4.0 3.8e-23 81.8 2.8 3.8 3 1 1 4 4 4 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 KZN90283.1 - 1.5e-16 59.3 1.9 2.9e-16 58.5 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KZN90283.1 - 1.3e-13 50.2 5.4 1.3e-13 50.2 3.7 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) HSP9_HSP12 PF04119.7 KZN90284.1 - 0.015 15.4 0.4 0.66 10.1 0.1 2.5 2 1 0 2 2 2 0 Heat shock protein 9/12 Ipi1_N PF12333.3 KZN90285.1 - 3.7e-31 107.1 0.0 5e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 KZN90285.1 - 0.12 12.5 1.0 5.8 7.2 0.1 2.9 3 0 0 3 3 3 0 HEAT repeat Robl_LC7 PF03259.12 KZN90287.1 - 8.4e-08 31.6 0.2 0.0035 16.8 0.0 3.1 3 0 0 3 3 3 3 Roadblock/LC7 domain Aminotran_5 PF00266.14 KZN90288.1 - 1.1e-55 188.8 0.0 1.7e-55 188.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN90288.1 - 0.00059 18.8 0.1 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KZN90288.1 - 0.00067 18.0 0.0 0.0011 17.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Cyclin PF08613.6 KZN90289.1 - 5.1e-14 52.9 0.0 1.3e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN90289.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Transp_cyt_pur PF02133.10 KZN90290.1 - 1.8e-87 293.7 40.8 2.1e-87 293.5 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyrid_oxidase_2 PF13883.1 KZN90291.1 - 3.3e-33 114.8 0.0 5.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SEN1_N PF12726.2 KZN90292.1 - 6.1e-228 758.5 1.0 8e-228 758.1 0.7 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KZN90292.1 - 5.8e-69 232.2 1.2 5.8e-69 232.2 0.8 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KZN90292.1 - 6.4e-62 208.4 0.0 1.2e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN90292.1 - 6.1e-11 41.9 0.3 2.3e-10 40.0 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KZN90292.1 - 3.4e-09 36.5 0.2 5e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KZN90292.1 - 2e-07 30.7 0.2 0.022 14.3 0.1 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KZN90292.1 - 2.5e-06 27.0 0.2 0.00027 20.3 0.1 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T2SE PF00437.15 KZN90292.1 - 0.0012 17.8 0.0 0.0027 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KZN90292.1 - 0.0072 15.3 0.4 0.1 11.5 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KZN90292.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KZN90292.1 - 0.029 14.5 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KZN90292.1 - 0.037 14.3 0.5 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KZN90292.1 - 0.041 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KZN90292.1 - 0.059 13.1 0.2 0.48 10.2 0.2 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 KZN90292.1 - 0.085 12.3 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-CCHC_3 PF13917.1 KZN90292.1 - 0.88 9.3 17.3 0.13 12.0 0.2 3.7 1 1 2 3 3 3 0 Zinc knuckle HAD PF12710.2 KZN90293.1 - 3e-13 50.3 0.0 6.5e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN90293.1 - 1.9e-11 43.7 0.0 4.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KZN90293.1 - 8.3e-11 42.7 1.7 2.2e-09 38.0 1.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KZN90293.1 - 9.7e-11 41.1 0.0 3.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD_2 PF13419.1 KZN90293.1 - 0.022 15.0 0.1 0.058 13.6 0.1 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN90293.1 - 0.04 13.5 0.4 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 KZN90295.1 - 2.4e-58 196.7 9.1 2.7e-58 196.5 6.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit WAPL PF07814.8 KZN90295.1 - 0.0056 15.4 1.9 0.0071 15.1 1.3 1.1 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF4288 PF14119.1 KZN90295.1 - 0.18 11.9 7.2 7.6 6.7 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) DUF2188 PF09954.4 KZN90295.1 - 0.48 10.3 2.0 24 4.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Mg_trans_NIPA PF05653.9 KZN90296.1 - 2.6e-14 52.8 7.9 2.2e-10 40.0 1.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KZN90296.1 - 7.3e-06 26.0 0.5 7.3e-06 26.0 0.3 2.7 3 0 0 3 3 3 1 EamA-like transporter family Multi_Drug_Res PF00893.14 KZN90296.1 - 6.7 7.2 8.8 5.9 7.4 0.2 3.1 2 1 1 3 3 3 0 Small Multidrug Resistance protein SRF-TF PF00319.13 KZN90297.1 - 1.3e-23 81.9 0.2 1.9e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KZN90297.1 - 0.11 10.5 0.1 0.15 10.0 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF604 PF04646.7 KZN90298.1 - 7.1e-06 25.4 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 KZN90298.1 - 0.00025 20.3 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.8 KZN90298.1 - 0.031 13.8 0.2 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Lactamase_B_2 PF12706.2 KZN90299.1 - 2.5e-25 89.1 0.0 3.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN90299.1 - 9.8e-10 38.3 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Isochorismatase PF00857.15 KZN90300.1 - 7.5e-40 136.6 0.1 8.5e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family SLAC1 PF03595.12 KZN90301.1 - 9.8e-103 343.2 53.4 1.1e-102 343.0 37.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_2 PF07719.12 KZN90302.1 - 1.7e-09 36.8 16.5 0.057 13.3 0.0 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KZN90302.1 - 9.1e-09 34.8 14.6 1.4e-05 24.6 0.3 6.2 5 2 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KZN90302.1 - 8e-06 26.3 20.6 0.25 12.0 0.0 6.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN90302.1 - 0.00032 20.2 6.0 0.071 12.9 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KZN90302.1 - 0.00078 19.6 8.7 2.3 8.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN90302.1 - 0.0023 17.9 7.2 0.086 13.0 0.0 5.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN90302.1 - 0.0023 17.8 9.5 0.11 12.4 0.1 5.6 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN90302.1 - 0.0054 16.2 10.3 6.6 6.5 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN90302.1 - 3.2 8.3 8.2 43 4.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KZN90303.1 - 1.5e-10 40.4 0.3 4.8e-10 38.7 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KZN90304.1 - 2.4e-60 204.3 3.0 3.1e-60 203.9 2.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN90304.1 - 5.1e-05 22.7 6.3 0.00046 19.6 4.3 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HATPase_c PF02518.21 KZN90304.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF229 PF02995.12 KZN90304.1 - 0.12 10.8 1.0 0.22 9.8 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF229) DUF3285 PF11688.3 KZN90304.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Glyco_hydro_3 PF00933.16 KZN90305.1 - 1.2e-77 260.8 0.0 1.7e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN90305.1 - 5.9e-58 196.0 0.0 8.2e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN90305.1 - 1e-16 60.6 0.1 2.6e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KZN90305.1 - 1.9e-10 40.5 0.0 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.19 KZN90306.1 - 3.9e-82 276.2 25.6 4.5e-82 276.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN90306.1 - 3.7e-15 55.4 36.7 3.3e-11 42.5 6.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN90307.1 - 2.8e-26 92.0 45.5 2.8e-26 92.0 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KZN90308.1 - 4.2e-32 111.8 0.0 5.3e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90308.1 - 9e-19 67.9 0.0 9.1e-15 54.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN90308.1 - 3.1e-17 62.6 0.0 2.1e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KZN90308.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase Ndr PF03096.9 KZN90308.1 - 0.0024 16.3 0.0 0.043 12.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 KZN90308.1 - 0.039 13.7 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Transferase PF02458.10 KZN90309.1 - 0.0092 14.4 0.0 0.079 11.3 0.0 1.9 1 1 0 1 1 1 1 Transferase family Prenyltrans_2 PF13249.1 KZN90310.1 - 2.5e-46 156.7 15.7 2e-15 57.1 0.1 5.3 2 1 3 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 KZN90310.1 - 2.8e-31 107.7 6.2 3.4e-14 52.7 0.0 5.8 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 KZN90310.1 - 2.3e-30 103.8 17.8 2e-09 36.8 0.1 7.6 8 0 0 8 8 8 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 KZN90310.1 - 1.1e-08 34.5 3.8 0.89 8.6 0.0 5.6 4 1 1 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 KZN90310.1 - 1.4e-06 27.7 0.0 0.21 10.7 0.0 4.8 5 0 0 5 5 5 2 A-macroglobulin complement component p450 PF00067.17 KZN90311.1 - 5.2e-40 137.3 0.0 1.2e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SNN_linker PF09050.5 KZN90312.1 - 0.04 13.4 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 Stannin unstructured linker MFS_1 PF07690.11 KZN90313.1 - 2.6e-33 115.2 27.2 4.1e-33 114.5 18.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 KZN90314.1 - 1.8e-80 262.2 16.3 8.3e-14 50.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 KZN90314.1 - 4.4e-06 26.2 0.8 0.57 9.9 0.0 4.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KZN90314.1 - 3.3e-05 22.2 8.4 0.16 10.0 0.1 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KZN90314.1 - 7.5e-05 21.9 0.5 16 4.9 0.0 4.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature eIF2A PF08662.6 KZN90314.1 - 8.5e-05 22.3 0.0 0.12 12.1 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KZN90314.1 - 9e-05 21.3 1.3 0.039 12.7 0.9 3.4 1 1 0 1 1 1 1 Nup133 N terminal like DUF1652 PF07865.6 KZN90314.1 - 0.00024 20.6 0.0 11 5.7 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) TruB_C PF09142.6 KZN90314.1 - 0.0038 16.8 0.0 15 5.3 0.0 4.3 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal DUF1258 PF06869.7 KZN90314.1 - 0.0038 16.3 0.0 0.049 12.7 0.0 2.6 1 1 1 3 3 3 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 KZN90314.1 - 0.0099 15.3 2.1 0.022 14.2 0.6 2.1 1 1 1 2 2 2 1 PQQ-like domain Ribosomal_L21e PF01157.13 KZN90314.1 - 0.013 15.2 0.0 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L21e Flagellin_N PF00669.15 KZN90314.1 - 0.079 12.7 0.5 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cytochrom_D1 PF02239.11 KZN90314.1 - 0.079 11.2 0.1 1.9 6.6 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain MBD PF01429.14 KZN90314.1 - 0.12 11.8 0.0 6 6.4 0.0 3.3 2 1 1 3 3 3 0 Methyl-CpG binding domain FMN_dh PF01070.13 KZN90315.1 - 7.2e-123 409.9 0.0 8.2e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 KZN90315.1 - 4.5e-05 22.6 0.0 0.026 13.6 0.2 2.7 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 KZN90315.1 - 7.8e-05 21.9 0.4 0.00012 21.3 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KZN90315.1 - 0.00077 18.4 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KZN90315.1 - 0.0013 17.7 0.3 0.0062 15.4 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KZN90315.1 - 0.015 14.5 0.1 0.4 9.8 0.0 2.7 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 KZN90315.1 - 0.12 11.3 0.2 0.76 8.6 0.1 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IGPS PF00218.16 KZN90315.1 - 0.15 11.0 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Lipase_3 PF01764.20 KZN90316.1 - 2.9e-15 56.1 0.0 7.4e-14 51.5 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KZN90316.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-H2C2_2 PF13465.1 KZN90317.1 - 1.8e-05 24.8 0.9 1.8e-05 24.8 0.6 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KZN90317.1 - 0.0001 22.4 15.5 0.0024 18.0 3.1 3.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN90317.1 - 0.015 15.6 13.4 0.075 13.4 1.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 KZN90317.1 - 0.14 12.4 4.1 0.32 11.2 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KZN90317.1 - 0.21 11.5 2.2 3.1 7.8 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 KZN90317.1 - 0.26 11.0 11.9 0.85 9.4 2.3 2.5 1 1 1 2 2 2 0 BED zinc finger PAT1 PF09770.4 KZN90317.1 - 0.65 8.1 16.3 0.75 7.9 11.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SMC_N PF02463.14 KZN90318.1 - 8.6e-23 80.7 0.0 2.3e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KZN90318.1 - 4.9e-15 56.3 12.4 4.9e-15 56.3 8.6 4.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 KZN90318.1 - 2.3e-05 24.5 0.6 0.0013 18.7 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KZN90318.1 - 0.0003 20.2 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KZN90318.1 - 0.044 12.2 60.3 0.12 10.8 17.7 3.7 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KZN90318.1 - 0.057 12.8 1.3 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KZN90318.1 - 0.088 13.1 0.0 0.088 13.1 0.0 4.6 3 2 0 3 3 3 0 ABC transporter AAA_19 PF13245.1 KZN90318.1 - 0.14 11.9 0.1 0.47 10.2 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain BTB PF00651.26 KZN90319.1 - 1.5e-26 92.5 0.0 8.6e-13 48.2 0.3 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 KZN90319.1 - 4.2e-10 39.8 0.0 9.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90319.1 - 1.5e-08 33.9 0.1 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KZN90319.1 - 6.1e-08 32.6 0.0 3e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN90319.1 - 2.2e-07 31.2 0.0 4.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90319.1 - 0.00015 21.6 0.0 0.0035 17.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 KZN90320.1 - 9.1e-58 195.4 0.3 1.8e-57 194.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90320.1 - 1.7e-36 125.6 0.0 6.1e-26 91.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KZN90320.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN90320.1 - 0.11 12.1 0.6 0.85 9.2 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Wbp11 PF09429.5 KZN90321.1 - 5.1e-23 80.8 13.5 5.1e-23 80.8 9.3 2.4 2 1 1 3 3 3 1 WW domain binding protein 11 Syntaxin PF00804.20 KZN90322.1 - 0.018 15.2 3.4 0.94 9.6 0.4 2.6 1 1 1 2 2 2 0 Syntaxin Baculo_PEP_C PF04513.7 KZN90322.1 - 0.032 14.0 0.3 0.41 10.4 0.2 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 KZN90322.1 - 0.044 13.1 0.2 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region Glyco_hydro_3_C PF01915.17 KZN90322.1 - 0.044 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF1664 PF07889.7 KZN90322.1 - 0.045 13.5 1.3 0.52 10.1 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PhaP_Bmeg PF09602.5 KZN90322.1 - 0.1 12.3 0.5 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ING PF12998.2 KZN90322.1 - 0.25 11.6 2.2 2 8.7 0.1 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ORF11CD3 PF10549.4 KZN90322.1 - 0.73 9.6 0.1 0.73 9.6 0.1 3.0 4 0 0 4 4 4 0 ORF11CD3 domain Rpr2 PF04032.11 KZN90323.1 - 1.4e-25 88.9 0.6 2.3e-25 88.2 0.4 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 KZN90323.1 - 0.15 11.8 1.2 0.99 9.1 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal DEAD PF00270.24 KZN90324.1 - 2.4e-35 121.5 0.4 4e-35 120.7 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90324.1 - 8.4e-25 86.4 0.0 4.4e-23 80.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN90324.1 - 7.6e-07 29.1 0.2 2.2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ApbA PF02558.11 KZN90325.1 - 9e-25 86.8 0.0 1.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KZN90325.1 - 7.8e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 KZN90326.1 - 1.3e-21 76.5 2.1 1.7e-21 76.1 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Mating_C PF12737.2 KZN90326.1 - 0.0051 15.7 0.2 0.0062 15.4 0.1 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 His_Phos_1 PF00300.17 KZN90327.1 - 4.7e-30 104.7 0.0 5.9e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AdoMet_MTase PF07757.8 KZN90328.1 - 8.8e-27 93.4 0.0 1.8e-26 92.4 0.0 1.5 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CorA PF01544.13 KZN90329.1 - 3.6e-07 29.5 0.1 6.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WH1 PF00568.18 KZN90331.1 - 1.4e-28 98.8 0.0 2.1e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KZN90331.1 - 0.027 14.0 4.0 0.13 11.9 2.8 2.2 1 1 0 1 1 1 0 WH2 motif ERCC4 PF02732.10 KZN90334.1 - 7.1e-25 87.4 0.0 3.8e-24 85.0 0.0 2.3 2 1 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 KZN90334.1 - 0.00028 20.9 0.0 0.00086 19.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Peptidase_S41 PF03572.13 KZN90335.1 - 7.5e-09 35.2 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 eIF-1a PF01176.14 KZN90336.1 - 1.2e-28 98.3 0.1 1.6e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3124 PF11322.3 KZN90336.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) PTCB-BRCT PF12738.2 KZN90337.1 - 5.7e-12 45.3 0.0 1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KZN90337.1 - 7.6e-07 29.1 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 KZN90337.1 - 0.00075 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 KZN90337.1 - 0.00075 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF1509 PF07420.6 KZN90337.1 - 2.1 7.5 13.3 3.3 6.8 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) CDC27 PF09507.5 KZN90337.1 - 6.1 5.9 16.8 8.6 5.4 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Aminotran_1_2 PF00155.16 KZN90338.1 - 4.3e-75 252.9 0.0 4.8e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.8 KZN90339.1 - 5.3e-56 189.5 0.0 6.8e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN90339.1 - 4.3e-05 22.8 0.0 0.0031 16.7 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KZN90339.1 - 0.00012 22.0 0.3 0.00017 21.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lyase_1 PF00206.15 KZN90340.1 - 3.1e-111 371.5 0.0 4.8e-111 370.8 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KZN90340.1 - 8e-22 77.0 0.0 2.5e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_1 PF00583.19 KZN90341.1 - 1.9e-09 37.4 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN90341.1 - 6.9e-09 35.7 0.3 1.2e-08 35.0 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN90341.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.15 KZN90342.1 - 3.8e-30 103.5 0.4 3.8e-30 103.5 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e SIMPL PF04402.9 KZN90342.1 - 0.3 10.9 12.0 0.36 10.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF1117 PF06547.7 KZN90342.1 - 3.6 7.7 5.9 6.4 6.9 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1117) UQ_con PF00179.21 KZN90343.1 - 1.3e-46 157.5 0.0 1.5e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN90343.1 - 6.7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KZN90343.1 - 0.011 15.3 0.1 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 KZN90343.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 KZN90344.1 - 5.3e-15 54.6 13.2 0.00022 20.9 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 KZN90344.1 - 0.012 15.6 7.7 0.038 14.0 5.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN90344.1 - 0.025 14.4 7.5 0.07 12.9 5.2 1.8 1 0 0 1 1 1 0 Ring finger domain RWD PF05773.17 KZN90344.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Redoxin PF08534.5 KZN90345.1 - 5.6e-35 120.0 0.0 6e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KZN90345.1 - 1.7e-15 56.7 0.0 2.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family PS-DH PF14765.1 KZN90346.1 - 3e-58 197.3 0.0 6.2e-58 196.2 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 KZN90346.1 - 3.9e-58 196.9 0.0 1.4e-57 195.1 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN90346.1 - 5.7e-51 172.7 0.5 1.6e-50 171.2 0.4 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KZN90346.1 - 1.5e-48 165.7 0.0 3.2e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Beta-lactamase PF00144.19 KZN90346.1 - 3e-42 144.8 0.0 5.8e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.20 KZN90346.1 - 1.2e-41 142.4 4.9 2.3e-41 141.4 1.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN90346.1 - 3.5e-32 110.7 0.0 1e-31 109.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KZN90346.1 - 1.7e-17 63.6 0.0 5e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KZN90346.1 - 7.6e-16 57.8 0.0 1.6e-14 53.5 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN90346.1 - 3e-14 54.0 0.0 2.4e-13 51.0 0.0 2.7 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KZN90346.1 - 3.9e-12 46.1 0.0 1.2e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90346.1 - 2.1e-09 37.1 0.0 5.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN90346.1 - 4.9e-09 36.7 0.0 3.3e-07 30.8 0.0 3.7 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90346.1 - 9.9e-09 35.5 0.0 4.2e-08 33.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KZN90346.1 - 9.2e-08 32.2 0.0 2.8e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KZN90346.1 - 1.1e-06 28.9 0.1 3.8e-05 23.9 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 KZN90346.1 - 1.2e-05 24.9 0.1 2.8e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_26 PF13659.1 KZN90346.1 - 3.2e-05 23.9 0.0 0.00011 22.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN90346.1 - 0.00038 19.6 0.0 0.00081 18.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KZN90346.1 - 0.0098 14.8 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF938 PF06080.7 KZN90346.1 - 0.047 13.2 0.0 0.3 10.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF938) NAS PF03059.11 KZN90346.1 - 0.16 11.1 0.0 0.64 9.1 0.0 1.8 2 0 0 2 2 2 0 Nicotianamine synthase protein Methyltransf_16 PF10294.4 KZN90346.1 - 0.28 10.6 0.0 0.9 8.9 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase DUF3419 PF11899.3 KZN90347.1 - 6.4e-146 485.9 0.0 8.8e-146 485.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KZN90347.1 - 2.1e-11 43.8 0.0 1.7e-10 40.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90347.1 - 5.5e-08 32.5 0.0 1.8e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KZN90347.1 - 1.8e-07 31.5 0.0 6.2e-07 29.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN90347.1 - 3.1e-07 30.9 0.0 9.5e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90347.1 - 1.7e-05 25.2 0.0 0.00086 19.7 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN90347.1 - 1.8e-05 23.9 0.0 0.067 12.2 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KZN90347.1 - 0.0002 21.6 0.0 0.00064 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN90347.1 - 0.00043 20.2 0.0 0.0039 17.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 KZN90347.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 KZN90347.1 - 0.0032 17.0 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KZN90347.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KZN90348.1 - 5.3e-44 150.3 58.2 2.5e-43 148.1 37.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90348.1 - 4.3e-17 61.8 13.8 4.3e-17 61.8 9.6 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KZN90348.1 - 2.2e-15 55.9 19.8 3.6e-15 55.2 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) P5CR_dimer PF14748.1 KZN90349.1 - 6.4e-30 103.3 2.7 1.6e-29 102.0 0.8 2.2 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KZN90349.1 - 1.1e-12 48.2 0.2 4.5e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KZN90350.1 - 4e-08 32.5 0.1 9.9e-06 24.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN90350.1 - 8.4e-05 22.5 0.1 0.00041 20.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN90350.1 - 0.0075 16.3 0.2 0.029 14.4 0.1 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN90350.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN90350.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN90350.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 KZN90350.1 - 0.057 13.4 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KZN90350.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.16 KZN90350.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family YjeF_N PF03853.10 KZN90350.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.18 KZN90350.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 KZN90350.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1348 PF07080.6 KZN90352.1 - 1.8e-45 154.2 3.4 2.2e-45 154.0 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 KZN90352.1 - 1.2e-07 31.9 0.5 1.6e-07 31.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KZN90352.1 - 4.4e-06 27.0 1.7 6.8e-06 26.4 1.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain Pkinase PF00069.20 KZN90353.1 - 8.5e-70 234.8 0.0 1.4e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90353.1 - 1.1e-34 119.7 0.0 7.5e-33 113.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN90353.1 - 2.1e-05 24.3 0.1 0.0028 17.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN90353.1 - 0.00029 19.9 0.0 0.00068 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN90353.1 - 0.00079 18.4 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KZN90353.1 - 0.0043 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Zn_clus PF00172.13 KZN90354.1 - 8.9e-09 35.1 6.9 1.3e-08 34.6 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 KZN90355.1 - 5e-71 238.4 0.1 8.1e-38 129.9 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) SURF2 PF05477.6 KZN90355.1 - 0.5 9.4 4.3 1.1 8.3 3.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRM_6 PF14259.1 KZN90356.1 - 0.0006 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 KZN90357.1 - 4.2e-73 244.3 3.9 4.6e-73 244.1 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KZN90358.1 - 3.9e-56 190.1 0.1 4.9e-56 189.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN90358.1 - 1.4e-19 70.6 2.5 6.6e-18 65.1 1.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KZN90358.1 - 1.2e-11 43.8 0.0 3.8e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Atg14 PF10186.4 KZN90358.1 - 1.4 7.7 9.5 2.5 6.9 6.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 4HBT PF03061.17 KZN90359.1 - 2.4e-06 27.5 0.1 4.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.8 KZN90360.1 - 2.7e-38 131.5 27.8 3.3e-38 131.2 19.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KZN90360.1 - 4.1e-18 65.2 58.2 1.3e-17 63.5 36.6 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90360.1 - 1.2e-10 40.5 11.4 1.2e-10 40.5 7.9 3.7 3 1 1 4 4 4 2 Sugar (and other) transporter POP1 PF06978.6 KZN90361.1 - 3e-64 216.1 18.7 6.2e-64 215.1 13.0 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KZN90361.1 - 3.9e-29 100.3 0.4 1.2e-28 98.7 0.3 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF1690 PF07956.6 KZN90362.1 - 6.9e-28 97.4 5.9 2.5e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 KZN90362.1 - 0.0068 16.4 3.8 0.34 10.8 0.1 2.1 2 0 0 2 2 2 2 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.13 KZN90362.1 - 0.0075 15.8 4.4 0.31 10.5 1.2 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Herpes_UL25 PF01499.11 KZN90362.1 - 0.13 10.5 1.6 0.16 10.2 1.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Matrilin_ccoil PF10393.4 KZN90362.1 - 0.71 9.2 3.5 18 4.8 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin LsmAD PF06741.8 KZN90362.1 - 1.3 9.2 4.3 1.3 9.1 1.6 1.9 2 0 0 2 2 2 0 LsmAD domain Hexokinase_2 PF03727.11 KZN90363.1 - 2.2e-72 243.1 0.0 3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KZN90363.1 - 8.8e-62 208.0 0.0 1.4e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Aldo_ket_red PF00248.16 KZN90364.1 - 1.3e-63 214.4 0.0 1.5e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KZN90365.1 - 2e-43 148.4 50.5 2e-43 148.4 35.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.19 KZN90365.1 - 9.1 5.6 21.4 0.039 13.3 3.0 2.9 2 1 1 3 3 3 0 Fatty acid desaturase Mpv17_PMP22 PF04117.7 KZN90366.1 - 2e-15 56.1 0.2 4.2e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family p450 PF00067.17 KZN90367.1 - 2.2e-65 220.9 0.0 3e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.17 KZN90367.1 - 0.16 11.7 1.6 0.33 10.8 1.1 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C2HC5 PF06221.8 KZN90368.1 - 1.2e-22 79.4 3.5 1.8e-22 78.8 2.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.6 KZN90369.1 - 2.1e-06 26.9 0.6 2.1e-06 26.9 0.4 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KZN90369.1 - 0.022 14.4 0.9 0.04 13.6 0.6 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KZN90369.1 - 0.25 11.6 1.5 7.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KZN90369.1 - 1 9.8 3.6 6.8 7.2 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Acetyltransf_1 PF00583.19 KZN90370.1 - 0.00058 19.8 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RRN3 PF05327.6 KZN90370.1 - 0.075 11.1 0.9 0.091 10.8 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NAD_binding_6 PF08030.7 KZN90371.1 - 1.4e-21 77.0 0.0 3.5e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KZN90371.1 - 3.9e-18 65.7 12.8 2.6e-17 63.0 6.7 2.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN90371.1 - 9e-16 57.6 0.0 2.1e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KZN90371.1 - 0.00024 21.6 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.16 KZN90372.1 - 8.8e-15 55.1 0.2 5e-14 52.7 0.1 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.8 KZN90373.1 - 1.2e-56 192.4 0.0 5.1e-56 190.3 0.0 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KZN90373.1 - 7e-06 25.3 2.2 7e-06 25.3 1.5 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) DUF3216 PF11505.3 KZN90373.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) UPF0233 PF06781.7 KZN90373.1 - 0.1 12.2 0.0 7.9 6.1 0.0 3.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Pro_isomerase PF00160.16 KZN90374.1 - 7.5e-51 172.4 0.0 8.7e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 KZN90376.1 - 2.4e-40 138.1 0.0 3.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KZN90376.1 - 0.037 14.0 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1469 PF07332.6 KZN90377.1 - 5.3 6.7 12.0 9.5 5.9 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Pox_P35 PF03213.9 KZN90377.1 - 6.1 5.7 5.4 26 3.6 1.4 2.1 2 0 0 2 2 2 0 Poxvirus P35 protein PIRT PF15099.1 KZN90377.1 - 7.7 5.7 6.3 13 5.0 4.3 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Aldedh PF00171.17 KZN90378.1 - 4.5e-76 256.0 0.0 5.6e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.3 KZN90379.1 - 1.4e-69 234.5 4.9 1.7e-69 234.2 3.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KZN90380.1 - 3.2e-57 194.0 0.0 3.7e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN90380.1 - 6.2e-06 26.2 0.0 0.02 14.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN90380.1 - 1.6e-05 24.7 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN90380.1 - 1.6e-05 24.8 0.0 5e-05 23.2 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KZN90380.1 - 2e-05 24.7 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KZN90380.1 - 6.3e-05 23.1 0.0 0.066 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN90380.1 - 0.00017 20.5 0.0 0.011 14.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A GMC_oxred_N PF00732.14 KZN90380.1 - 0.00022 20.5 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN90380.1 - 0.00046 19.1 0.1 0.004 16.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KZN90380.1 - 0.018 13.7 0.1 0.24 9.9 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 KZN90380.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family MFS_1 PF07690.11 KZN90381.1 - 9e-34 116.7 30.1 1.4e-33 116.1 20.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KZN90381.1 - 0.023 14.7 1.3 0.023 14.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ESSS PF10183.4 KZN90381.1 - 0.032 14.6 0.3 0.13 12.7 0.2 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3859 PF12975.2 KZN90381.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) Hydantoinase_B PF02538.9 KZN90382.1 - 5e-174 579.3 0.0 7.4e-174 578.8 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KZN90382.1 - 1.9e-95 319.2 1.3 2e-95 319.2 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KZN90382.1 - 1.7e-57 193.7 2.5 4.8e-56 189.0 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 KZN90382.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature His_Phos_2 PF00328.17 KZN90383.1 - 6.4e-37 127.6 0.0 8.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Nup35_RRM PF05172.8 KZN90384.1 - 0.00059 19.5 0.0 0.0015 18.2 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif NAC PF01849.13 KZN90385.1 - 3e-09 36.2 0.0 4.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 NAC domain NOGCT PF08155.6 KZN90385.1 - 0.046 13.4 0.5 0.098 12.3 0.2 1.6 2 0 0 2 2 2 0 NOGCT (NUC087) domain Epimerase PF01370.16 KZN90386.1 - 6.8e-26 91.1 0.0 1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN90386.1 - 1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN90386.1 - 3.2e-10 39.2 0.0 6.2e-10 38.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN90386.1 - 4.5e-09 35.5 0.0 1e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KZN90386.1 - 4.3e-07 29.1 0.0 7.1e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN90386.1 - 0.00012 21.1 0.0 0.0011 17.9 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KZN90386.1 - 0.076 12.9 0.0 0.35 10.7 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KZN90386.1 - 0.095 11.9 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 KZN90387.1 - 2.7e-19 69.6 0.2 2.7e-17 63.1 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90387.1 - 1.4e-08 34.5 0.1 3e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KZN90387.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KZN90387.1 - 0.002 17.6 0.0 0.0031 16.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KZN90387.1 - 0.0057 16.7 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NUMOD1 PF07453.8 KZN90387.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NUMOD1 domain FSH1 PF03959.8 KZN90388.1 - 4.5e-35 121.0 0.0 5.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KZN90388.1 - 5.3e-05 23.2 0.0 0.0004 20.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KZN90388.1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Synaptobrevin PF00957.16 KZN90389.1 - 5.8e-33 112.3 0.8 6.7e-33 112.1 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1035 PF06281.7 KZN90389.1 - 0.75 9.6 3.5 1.2 8.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF619 PF04768.8 KZN90390.1 - 2.8e-54 183.0 0.2 5.9e-54 182.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KZN90390.1 - 6.4e-30 103.9 0.0 2.7e-29 101.9 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KZN90390.1 - 3.1e-24 85.8 0.0 5.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KZN90390.1 - 0.023 14.5 0.0 0.083 12.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 KZN90390.1 - 0.068 13.6 0.0 0.26 11.8 0.0 2.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rad21_Rec8_N PF04825.8 KZN90391.1 - 4.1e-29 100.7 0.0 8.1e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KZN90391.1 - 0.0022 17.1 0.0 0.0063 15.6 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Foie-gras_1 PF11817.3 KZN90391.1 - 0.012 15.1 0.1 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF3237 PF11578.3 KZN90392.1 - 5.5e-37 126.3 0.0 8.3e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 KZN90392.1 - 1.4e-07 31.1 2.3 0.0048 16.6 0.2 2.3 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 KZN90392.1 - 0.024 14.7 4.2 2.4 8.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 KZN90392.1 - 0.15 12.1 0.6 1.4 8.9 0.4 2.4 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein Fungal_trans PF04082.13 KZN90393.1 - 0.00017 20.5 1.1 0.0013 17.6 0.2 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Chitin_synth_1 PF01644.12 KZN90394.1 - 4.3e-68 228.2 0.0 6.2e-68 227.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KZN90394.1 - 4.7e-28 97.8 0.1 4.1e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KZN90394.1 - 5.3e-26 90.1 0.1 1.5e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KZN90394.1 - 6.8e-12 45.4 0.0 6.8e-12 45.4 0.0 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN90394.1 - 7.9e-09 35.6 0.0 1.8e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 eIF-4B PF06273.6 KZN90395.1 - 0.079 11.7 1.3 0.11 11.2 0.9 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF515 PF04415.7 KZN90395.1 - 0.7 8.0 2.3 0.8 7.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ICL PF00463.16 KZN90396.1 - 3.4e-190 632.7 0.0 4e-190 632.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KZN90396.1 - 3.5e-10 39.5 0.0 5.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KZN90396.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Fungal_trans_2 PF11951.3 KZN90398.1 - 1.5e-55 188.3 0.3 2e-55 187.9 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_3 PF13417.1 KZN90399.1 - 2.3e-09 37.3 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN90399.1 - 1.6e-08 34.3 0.0 4.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN90399.1 - 1.7e-07 31.0 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN90399.1 - 9.2e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KZN90399.1 - 6.9e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN90399.1 - 5e-05 23.7 0.0 9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPP_enzyme_N PF02776.13 KZN90400.1 - 3.7e-55 186.0 0.2 2.7e-54 183.2 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KZN90400.1 - 5.4e-45 152.6 0.1 1.8e-43 147.7 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN90400.1 - 6.6e-41 139.2 0.0 1.3e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 KZN90400.1 - 0.0038 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Molybdopterin PF00384.17 KZN90400.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Aminotran_1_2 PF00155.16 KZN90401.1 - 1.4e-70 238.0 0.0 1.7e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KZN90401.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase EutQ PF06249.7 KZN90402.1 - 8.1e-12 44.9 0.0 9.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KZN90402.1 - 4.4e-10 38.7 0.1 5.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KZN90402.1 - 1.7e-05 24.2 0.1 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KZN90402.1 - 0.0045 16.6 0.0 0.011 15.3 0.0 1.6 1 1 1 2 2 2 1 Cupin Cupin_1 PF00190.17 KZN90402.1 - 0.07 12.5 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Pirin PF02678.11 KZN90402.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Pirin Pkinase PF00069.20 KZN90403.1 - 1e-55 188.7 0.0 8.1e-55 185.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90403.1 - 4.9e-28 97.9 0.1 1.5e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KZN90403.1 - 2.1e-06 28.1 0.2 6.1e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KZN90403.1 - 0.0005 19.1 0.1 0.0062 15.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN90403.1 - 0.0014 18.3 3.2 0.34 10.5 0.0 3.6 3 1 1 4 4 4 2 Phosphotransferase enzyme family ORC6 PF05460.8 KZN90403.1 - 8.5 5.3 9.5 0.12 11.4 1.3 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF1687 PF07955.6 KZN90404.1 - 5e-13 49.1 0.2 2.6e-12 46.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) OSCP PF00213.13 KZN90404.1 - 0.046 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit FAD_binding_8 PF08022.7 KZN90405.1 - 3e-20 72.0 0.0 5.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KZN90405.1 - 2e-16 60.2 0.0 3.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KZN90405.1 - 5.1e-16 58.8 13.9 1.2e-15 57.7 9.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KZN90405.1 - 0.0013 18.8 0.0 0.0058 16.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Ctr PF04145.10 KZN90406.1 - 6.8e-36 123.4 0.2 8.4e-36 123.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family AATase PF07247.7 KZN90408.1 - 1.5e-28 99.6 0.0 4.6e-28 98.0 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KZN90408.1 - 0.00056 18.8 0.1 0.002 17.0 0.0 1.8 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 KZN90408.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Abhydrolase_2 PF02230.11 KZN90409.1 - 4e-48 163.7 0.0 4.6e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KZN90409.1 - 1.9e-10 40.6 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN90409.1 - 1.3e-08 34.3 0.1 2.4e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KZN90409.1 - 1.6e-06 28.1 0.0 0.0085 15.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family LIP PF03583.9 KZN90409.1 - 5.8e-05 22.4 0.0 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase BAAT_C PF08840.6 KZN90409.1 - 0.0077 15.9 0.2 0.25 11.0 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 KZN90409.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.13 KZN90409.1 - 0.0088 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KZN90409.1 - 0.0089 15.6 0.0 0.032 13.8 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 KZN90409.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.3 KZN90409.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2920 PF11144.3 KZN90409.1 - 0.061 12.3 0.0 1.9 7.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Cutinase PF01083.17 KZN90409.1 - 0.069 12.8 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Cutinase Abhydrolase_4 PF08386.5 KZN90409.1 - 0.11 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein CBP4 PF07960.6 KZN90410.1 - 3.2e-34 117.3 2.3 3.5e-34 117.1 1.6 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 KZN90410.1 - 0.013 15.1 0.9 0.019 14.5 0.0 1.6 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) G6PD_bact PF10786.4 KZN90410.1 - 0.077 12.4 4.2 0.085 12.2 2.9 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) OPA3 PF07047.7 KZN90410.1 - 0.14 11.9 3.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) MMtag PF10159.4 KZN90410.1 - 1.4 8.9 8.9 0.83 9.7 4.9 1.5 1 1 0 1 1 1 0 Kinase phosphorylation protein Sel1 PF08238.7 KZN90411.1 - 5.1e-44 147.7 26.9 2e-07 31.4 0.0 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.1 KZN90411.1 - 0.073 13.1 2.0 0.19 11.8 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LigB PF02900.13 KZN90412.1 - 1.1e-49 168.8 0.0 1.4e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 KZN90413.1 - 3.1e-13 49.2 0.0 3.9e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 KZN90414.1 - 6e-44 148.8 0.3 8e-44 148.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF2863 PF11062.3 KZN90414.1 - 0.0065 14.6 0.3 0.22 9.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2863) Glyco_hydro_28 PF00295.12 KZN90415.1 - 2.2e-51 174.7 6.2 5.5e-51 173.4 4.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KZN90415.1 - 0.5 10.0 15.4 2.4 7.8 10.7 2.1 1 1 0 1 1 1 0 Right handed beta helix region Transferase PF02458.10 KZN90416.1 - 5.1e-12 44.9 0.0 1.1e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Transferase family FAD_binding_3 PF01494.14 KZN90418.1 - 1.7e-22 79.9 0.0 4.6e-21 75.2 0.0 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN90418.1 - 1.2e-06 27.6 0.3 0.0027 16.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KZN90418.1 - 6.3e-05 22.2 0.2 0.01 14.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KZN90418.1 - 0.00018 20.5 0.0 0.00046 19.2 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN90418.1 - 0.00026 20.9 0.1 0.00085 19.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN90418.1 - 0.0042 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KZN90418.1 - 0.0072 15.1 0.0 0.069 11.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KZN90418.1 - 0.0089 15.9 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN90418.1 - 0.016 15.5 0.5 0.077 13.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN90418.1 - 0.032 13.0 0.2 0.049 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KZN90418.1 - 0.068 11.7 0.1 7.6 5.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UbiA PF01040.13 KZN90419.1 - 2.6e-30 105.5 17.8 3.3e-30 105.1 12.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family adh_short PF00106.20 KZN90420.1 - 4e-25 88.6 0.6 7.1e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN90420.1 - 4.5e-22 78.9 0.4 6.1e-22 78.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN90420.1 - 1.4e-07 31.3 1.9 1.1e-06 28.4 1.3 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KZN90420.1 - 0.011 15.4 0.7 0.011 15.4 0.5 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KZN90421.1 - 1.1e-11 44.6 0.1 3.3e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN90421.1 - 5.6e-10 38.3 0.0 7.7e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN90421.1 - 3.5e-07 30.3 0.1 6e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN90421.1 - 6.4e-05 22.3 0.2 9.3e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KZN90421.1 - 0.0002 20.3 0.3 0.048 12.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 KZN90421.1 - 0.00037 20.4 0.1 0.00073 19.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90421.1 - 0.0013 18.4 1.7 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 KZN90422.1 - 1.6e-71 240.7 0.9 1.6e-71 240.7 0.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KZN90422.1 - 6e-37 126.1 0.0 1.4e-36 124.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KZN90422.1 - 1.8e-22 80.0 0.1 6.8e-21 74.9 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 KZN90422.1 - 6.3e-22 78.0 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 KZN90422.1 - 2.6e-17 63.1 0.0 8.2e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 KZN90422.1 - 8.5e-16 58.1 0.0 1.9e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold PP-binding PF00550.20 KZN90422.1 - 2.1e-14 53.5 0.5 4.8e-14 52.3 0.4 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 KZN90422.1 - 7.3e-11 42.0 0.1 2.7e-09 36.9 0.0 2.9 3 0 0 3 3 2 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 KZN90422.1 - 1.1e-09 38.6 0.0 2.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN90422.1 - 9.5e-09 35.1 0.0 2.8e-08 33.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KZN90422.1 - 1.7e-08 33.9 0.0 1.6e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 KZN90422.1 - 4.4e-08 33.6 0.0 1.7e-07 31.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90422.1 - 5.3e-08 32.5 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KZN90422.1 - 5.6e-08 32.9 1.5 2.1e-07 31.0 0.2 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KZN90422.1 - 1.5e-06 27.6 0.0 0.00039 19.7 0.0 3.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Thiolase_N PF00108.18 KZN90422.1 - 1.1e-05 24.5 0.3 2.8e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 KZN90422.1 - 9.6e-05 22.6 0.0 0.00029 21.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN90422.1 - 0.00023 20.3 0.0 0.00053 19.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Abhydrolase_2 PF02230.11 KZN90422.1 - 0.00044 19.7 0.0 0.0039 16.6 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_16 PF10294.4 KZN90422.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase LIP PF03583.9 KZN90422.1 - 0.0024 17.1 0.0 0.0056 15.9 0.0 1.5 1 0 0 1 1 1 1 Secretory lipase Thioesterase PF00975.15 KZN90422.1 - 0.036 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain RrnaAD PF00398.15 KZN90422.1 - 0.27 10.2 0.0 0.53 9.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ABC2_membrane PF01061.19 KZN90423.1 - 2.4e-76 255.5 57.0 1.8e-41 141.6 14.3 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 KZN90423.1 - 5.8e-39 133.5 0.0 8.5e-18 64.9 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KZN90423.1 - 6.9e-30 102.7 6.9 1.8e-27 95.0 0.0 2.9 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 KZN90423.1 - 1.4e-07 31.1 0.0 0.0016 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KZN90423.1 - 3.7e-06 26.2 12.7 3.7e-06 26.2 8.8 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.1 KZN90423.1 - 3.7e-05 23.6 0.1 0.0082 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN90423.1 - 4.3e-05 22.7 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KZN90423.1 - 4.4e-05 24.3 0.0 0.018 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KZN90423.1 - 0.00021 20.8 0.2 0.00097 18.6 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_2 PF12679.2 KZN90423.1 - 0.0013 17.6 13.2 0.0015 17.4 1.2 3.2 2 2 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KZN90423.1 - 0.0028 17.6 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_19 PF13245.1 KZN90423.1 - 0.0029 17.2 0.1 0.49 10.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KZN90423.1 - 0.0038 16.7 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 KZN90423.1 - 0.0047 16.8 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KZN90423.1 - 0.0051 17.1 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN90423.1 - 0.0058 16.1 0.8 0.33 10.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN90423.1 - 0.0074 16.2 0.2 0.54 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KZN90423.1 - 0.0079 16.3 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 KZN90423.1 - 0.02 15.0 0.2 0.35 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KZN90423.1 - 0.026 14.1 1.7 2.5 7.7 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 KZN90423.1 - 0.047 13.2 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KZN90423.1 - 0.12 11.9 1.2 0.54 9.8 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KZN90423.1 - 0.13 12.1 0.0 8.3 6.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain SMC_N PF02463.14 KZN90423.1 - 0.13 11.4 0.1 0.9 8.7 0.0 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KZN90423.1 - 0.14 12.3 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KZN90423.1 - 0.22 10.9 0.2 10 5.5 0.1 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family p450 PF00067.17 KZN90424.1 - 1.5e-41 142.3 0.0 2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 KZN90425.1 - 6.8e-17 62.0 0.0 9e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN90425.1 - 0.0014 17.6 0.0 0.0071 15.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KZN90425.1 - 0.0021 16.9 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KZN90425.1 - 0.0036 17.4 0.2 2.2 8.3 0.1 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN90425.1 - 0.0095 14.4 0.1 0.023 13.1 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KZN90425.1 - 0.017 14.8 0.2 5 6.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KZN90425.1 - 0.038 12.8 0.4 0.52 9.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 KZN90425.1 - 1.5 7.6 4.6 3.4 6.4 0.3 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KZN90426.1 - 3.1e-12 45.9 0.3 6e-12 44.9 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90426.1 - 1.6e-07 31.1 9.1 1.6e-07 31.1 6.3 2.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KZN90426.1 - 1e-05 25.5 14.0 9.7e-05 22.4 1.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KZN90426.1 - 0.0046 17.2 4.9 0.0046 17.2 3.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN90426.1 - 0.0083 16.3 4.8 0.0083 16.3 3.3 4.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.2 KZN90426.1 - 1.5 9.0 6.3 0.59 10.4 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pyr_redox_3 PF13738.1 KZN90427.1 - 6.9e-24 85.0 0.0 1.4e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN90427.1 - 6.9e-14 50.9 0.8 9.4e-13 47.1 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN90427.1 - 2.1e-12 46.8 0.0 4.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN90427.1 - 1.1e-09 37.6 0.4 2.4e-06 26.6 0.0 3.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN90427.1 - 1.2e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN90427.1 - 5.2e-07 29.5 0.1 4.5e-05 23.2 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KZN90427.1 - 0.00023 20.3 0.0 0.027 13.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KZN90427.1 - 0.00026 20.0 0.1 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KZN90427.1 - 0.00031 19.7 0.0 0.005 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KZN90427.1 - 0.042 13.9 0.0 57 3.8 0.0 3.8 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KZN90427.1 - 0.044 12.6 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KZN90427.1 - 0.067 11.6 0.0 0.16 10.4 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein zf-met PF12874.2 KZN90428.1 - 2.6e-21 75.0 33.4 3.2e-05 23.9 1.3 8.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN90428.1 - 2.8e-19 68.6 36.2 4.1e-07 29.9 1.3 8.1 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KZN90428.1 - 1.7e-16 59.2 33.5 0.046 14.0 1.7 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN90428.1 - 8.8e-16 57.2 42.7 0.0017 18.5 0.5 8.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KZN90428.1 - 1.6e-14 53.8 35.9 0.025 14.6 0.1 8.0 2 2 6 8 8 8 6 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KZN90428.1 - 4.1e-07 29.9 34.4 0.29 11.5 0.0 8.5 8 0 0 8 8 8 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 KZN90428.1 - 0.0016 18.2 36.1 0.36 10.8 0.4 8.1 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KZN90428.1 - 0.0018 17.9 25.4 0.27 10.9 0.2 6.5 7 0 0 7 7 7 4 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KZN90428.1 - 0.02 14.8 0.2 0.02 14.8 0.1 4.5 6 1 1 7 7 7 0 zinc-finger Penicillinase_R PF03965.11 KZN90428.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Penicillinase repressor zf-Di19 PF05605.7 KZN90428.1 - 0.35 11.0 0.2 0.35 11.0 0.1 5.3 5 1 1 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding CFEM PF05730.6 KZN90429.1 - 0.061 13.1 7.4 0.13 12.1 5.1 1.5 1 0 0 1 1 1 0 CFEM domain VSP PF03302.8 KZN90430.1 - 3.5e-05 22.6 3.4 6e-05 21.8 2.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD99L2 PF12301.3 KZN90430.1 - 0.044 13.4 0.3 0.077 12.6 0.2 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Cu_bind_like PF02298.12 KZN90430.1 - 0.094 12.5 0.3 0.29 10.9 0.2 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Pkinase PF00069.20 KZN90433.1 - 3.2e-29 101.8 0.0 4.3e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90433.1 - 4.6e-10 38.9 0.0 5.4e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase ILVD_EDD PF00920.16 KZN90434.1 - 9.1e-203 674.3 0.7 1.1e-202 674.1 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 KZN90434.1 - 0.017 15.0 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain DUF1380 PF07128.7 KZN90434.1 - 0.11 12.3 0.0 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1380) Acyl-CoA_dh_1 PF00441.19 KZN90435.1 - 3.8e-32 111.4 0.4 3.8e-32 111.4 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN90435.1 - 6.7e-18 65.3 0.2 1.7e-17 64.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KZN90435.1 - 2.5e-15 56.9 0.3 2.5e-15 56.9 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN90435.1 - 3.4e-13 48.8 0.2 8.1e-13 47.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SSB PF00436.20 KZN90437.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Single-strand binding protein family FAD_binding_4 PF01565.18 KZN90438.1 - 4.1e-20 71.6 3.3 7.4e-20 70.8 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN90438.1 - 1.8e-10 40.5 1.8 3.9e-10 39.4 1.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KZN90438.1 - 0.0046 16.1 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Aldo_ket_red PF00248.16 KZN90439.1 - 2.6e-42 144.5 0.0 2.9e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.2 KZN90440.1 - 9.3e-25 87.8 0.3 1.1e-24 87.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN90440.1 - 8.3e-11 41.8 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN90440.1 - 0.00054 19.6 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KZN90440.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 KZN90440.1 - 0.04 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Methyltransf_18 PF12847.2 KZN90442.1 - 1.1e-05 25.9 0.0 3.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90442.1 - 4.1e-05 23.2 0.0 8.6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN90442.1 - 5.3e-05 22.9 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN90442.1 - 0.00011 22.6 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN90442.1 - 0.0051 16.8 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90442.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN90442.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KZN90443.1 - 9.7e-49 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KZN90444.1 - 1.4e-12 47.8 2.1 2.2e-12 47.1 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90444.1 - 1.6e-07 31.1 1.3 2.3e-07 30.6 0.9 1.3 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.23 KZN90445.1 - 8.7e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN90445.1 - 0.0073 17.2 0.0 0.015 16.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KZN90447.1 - 3.3e-20 72.0 0.0 9.5e-20 70.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90447.1 - 8.5e-09 35.1 10.7 1.6e-08 34.3 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KZN90447.1 - 0.21 11.6 0.6 0.46 10.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) FAD_binding_7 PF03441.9 KZN90448.1 - 2.9e-100 335.0 1.4 5.1e-100 334.2 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KZN90448.1 - 2.4e-42 144.5 0.2 4.1e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Na_H_Exchanger PF00999.16 KZN90450.1 - 3.4e-61 206.8 44.6 4.9e-61 206.3 30.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aminotran_4 PF01063.14 KZN90451.1 - 7.6e-21 74.6 0.0 9.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV BNR_2 PF13088.1 KZN90451.1 - 0.0093 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain ADH_N PF08240.7 KZN90452.1 - 3.1e-27 94.4 2.0 5.3e-27 93.7 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN90452.1 - 3.4e-12 46.0 0.0 2.9e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN90452.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.1 KZN90452.1 - 0.0026 17.3 0.9 0.0066 16.0 0.6 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Methyltransf_18 PF12847.2 KZN90452.1 - 0.0096 16.4 0.0 0.03 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 KZN90453.1 - 3.1e-41 141.2 0.0 5.8e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KZN90453.1 - 8.7e-41 138.7 0.0 2.1e-40 137.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KZN90453.1 - 4.4e-20 71.8 0.0 9.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 KZN90453.1 - 0.0015 17.9 0.0 0.13 11.8 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 KZN90453.1 - 0.0016 17.9 0.1 0.093 12.1 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Cytokin_check_N PF10407.4 KZN90453.1 - 0.0078 15.8 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus YrbL-PhoP_reg PF10707.4 KZN90453.1 - 0.048 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_76 PF03663.9 KZN90454.1 - 3.1e-136 454.6 19.8 4e-136 454.2 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 KZN90454.1 - 0.0028 17.6 0.1 0.0065 16.4 0.1 1.6 1 0 0 1 1 1 1 Cloacin immunity protein Cpn60_TCP1 PF00118.19 KZN90455.1 - 3.1e-133 444.9 9.2 3.7e-133 444.7 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CO_deh_flav_C PF03450.12 KZN90455.1 - 0.21 11.5 3.7 0.31 10.9 0.2 2.7 2 1 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Pro_isomerase PF00160.16 KZN90456.1 - 3.3e-49 167.0 0.1 6.5e-49 166.0 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KZN90456.1 - 9e-16 57.0 1.6 7.7e-06 25.5 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KZN90456.1 - 0.057 11.5 0.0 1.1 7.2 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TMEM154 PF15102.1 KZN90457.1 - 0.0017 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Synaptobrevin PF00957.16 KZN90457.1 - 0.021 14.3 0.3 0.04 13.5 0.2 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF2207 PF09972.4 KZN90457.1 - 0.024 13.2 0.0 0.033 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rifin_STEVOR PF02009.11 KZN90457.1 - 0.05 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF3619 PF12279.3 KZN90457.1 - 0.058 13.4 0.2 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4381 PF14316.1 KZN90457.1 - 0.16 12.0 0.8 0.34 10.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Tetraspannin PF00335.15 KZN90457.1 - 1.1 8.5 7.8 6 6.0 0.1 1.9 1 1 1 2 2 2 0 Tetraspanin family DUF2981 PF11200.3 KZN90457.1 - 1.1 8.2 6.4 1.5 7.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MFS_1 PF07690.11 KZN90459.1 - 5.8e-25 87.7 32.3 3e-23 82.1 22.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Far-17a_AIG1 PF04750.9 KZN90460.1 - 1e-74 250.0 9.7 1.2e-74 249.8 6.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein TMEM107 PF14995.1 KZN90460.1 - 0.037 14.1 2.2 4.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein Claudin_2 PF13903.1 KZN90460.1 - 0.56 9.8 6.4 0.31 10.7 0.6 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans_2 PF11951.3 KZN90461.1 - 2.8e-52 177.6 0.2 8.1e-52 176.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90461.1 - 1.1e-09 38.0 7.9 2e-09 37.1 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 KZN90462.1 - 3.1e-34 118.2 0.0 3.9e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pam17 PF08566.5 KZN90463.1 - 3.7e-68 228.6 0.0 4.9e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Defensin_2 PF01097.13 KZN90464.1 - 8e-06 25.4 8.2 1.2e-05 24.8 5.7 1.4 1 1 0 1 1 1 1 Arthropod defensin DUF2667 PF10868.3 KZN90464.1 - 0.00017 21.8 0.9 0.00019 21.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2667) SLR1-BP PF07333.7 KZN90464.1 - 0.014 15.6 4.8 0.02 15.1 3.3 1.2 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF3602 PF12223.3 KZN90465.1 - 2.6e-19 69.4 8.4 1.3e-17 63.9 1.0 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Fungal_trans_2 PF11951.3 KZN90466.1 - 1.5e-07 30.3 0.0 2.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.3 KZN90467.1 - 1.4e-82 276.2 0.0 1.7e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor WD40 PF00400.27 KZN90469.1 - 3e-83 271.0 19.5 5.6e-14 51.4 0.0 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KZN90469.1 - 2.7e-09 36.9 1.0 0.0022 17.7 0.0 3.7 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KZN90469.1 - 4.3e-07 28.4 7.6 0.24 9.4 0.0 5.3 2 2 4 6 6 6 3 Nucleoporin Nup120/160 NLE PF08154.7 KZN90469.1 - 2.8e-06 27.2 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 KZN90469.1 - 0.017 15.1 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Rav1p_C PF12234.3 KZN90469.1 - 0.037 12.1 0.0 1.2 7.1 0.0 2.4 1 1 1 2 2 2 0 RAVE protein 1 C terminal MutS_III PF05192.13 KZN90470.1 - 1.5e-28 99.9 1.5 2.2e-28 99.4 1.0 1.2 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KZN90470.1 - 8.9e-09 35.5 0.1 2.6e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 MutS domain II MutS_V PF00488.16 KZN90471.1 - 4.3e-76 255.4 0.0 6e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN90471.1 - 9.4e-07 28.8 1.3 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KZN90471.1 - 2.8e-06 27.3 0.0 6.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV zf-C3HC4_3 PF13920.1 KZN90472.1 - 1.1e-05 25.0 9.0 1.1e-05 25.0 6.3 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 KZN90472.1 - 3.6 7.3 5.5 0.54 10.0 0.7 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain SWIB PF02201.13 KZN90473.1 - 1.8e-25 88.3 0.3 5.4e-25 86.8 0.1 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KZN90473.1 - 1.1e-14 53.9 0.9 1.9e-14 53.1 0.6 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF3275 PF11679.3 KZN90473.1 - 3.4 7.2 8.2 1.2 8.7 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) eIF2A PF08662.6 KZN90474.1 - 2.4e-39 135.0 6.9 3.3e-36 124.8 3.3 4.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 KZN90474.1 - 4.1e-06 26.6 0.0 8.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90474.1 - 5.5e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN90474.1 - 6.4e-06 25.7 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KZN90474.1 - 0.0054 16.5 0.1 1.5 8.8 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat CAP PF00188.21 KZN90475.1 - 6.1e-20 71.9 3.1 9e-20 71.4 2.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sec10 PF07393.6 KZN90476.1 - 1.6e-183 611.7 1.1 1.8e-183 611.5 0.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KZN90476.1 - 3.2e-05 23.5 0.0 7.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN90476.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cytochrom_C1 PF02167.10 KZN90477.1 - 5.4e-79 264.8 0.0 7.2e-79 264.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KZN90477.1 - 0.0064 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KZN90477.1 - 0.092 13.5 0.2 0.57 11.0 0.0 2.4 3 0 0 3 3 3 0 Cytochrome c AIG2_2 PF13772.1 KZN90478.1 - 0.0013 18.7 0.0 0.0086 16.1 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family DUF837 PF05769.6 KZN90479.1 - 0.0057 16.2 1.5 0.011 15.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF837) DAHP_synth_1 PF00793.15 KZN90480.1 - 6.9e-98 326.6 0.0 8.3e-98 326.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family F-box-like PF12937.2 KZN90481.1 - 1.9e-06 27.5 2.4 3e-06 26.8 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN90481.1 - 7.3e-05 22.3 0.1 0.00036 20.1 0.0 2.2 1 0 0 1 1 1 1 F-box domain DUF221 PF02714.10 KZN90483.1 - 1.4e-97 326.5 19.4 2.4e-97 325.7 13.4 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KZN90483.1 - 2e-44 150.8 0.2 7.3e-44 149.0 0.1 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KZN90483.1 - 2e-22 79.5 0.7 3.3e-22 78.7 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KZN90483.1 - 0.0036 17.2 0.0 0.93 9.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3545 PF12065.3 KZN90483.1 - 0.3 10.8 2.8 1.1 9.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) VirB3 PF05101.8 KZN90483.1 - 2.5 8.1 9.1 9 6.3 0.2 3.6 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein DUF1814 PF08843.6 KZN90484.1 - 4.8e-05 23.2 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) hDGE_amylase PF14701.1 KZN90486.1 - 2e-180 600.2 0.0 2.6e-180 599.8 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KZN90486.1 - 1.1e-111 373.1 0.0 1.9e-111 372.3 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KZN90486.1 - 9.5e-88 293.7 0.0 1.4e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KZN90486.1 - 3.4e-26 90.8 0.0 7.2e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KZN90486.1 - 5e-05 22.8 0.1 0.002 17.5 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KZN90487.1 - 8.3e-49 165.3 0.1 2.4e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KZN90487.1 - 3.5e-41 140.3 0.2 4.9e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLX9 PF15341.1 KZN90488.1 - 9e-33 113.2 10.6 1.1e-32 113.0 7.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Neugrin PF06413.6 KZN90488.1 - 0.0048 16.7 1.7 0.0067 16.2 1.2 1.2 1 0 0 1 1 1 1 Neugrin DUF2894 PF11445.3 KZN90488.1 - 0.058 13.6 5.8 0.075 13.2 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) AAA_2 PF07724.9 KZN90489.1 - 8.7e-37 126.6 0.0 9.8e-36 123.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KZN90489.1 - 1.7e-14 54.1 0.0 3.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KZN90489.1 - 1.4e-07 31.3 0.0 3.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KZN90489.1 - 5.8e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KZN90489.1 - 0.00019 20.6 0.1 0.01 15.0 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KZN90489.1 - 0.00027 21.0 0.3 0.01 15.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KZN90489.1 - 0.00034 20.1 0.0 0.087 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KZN90489.1 - 0.00053 20.8 0.1 0.0018 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KZN90489.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KZN90489.1 - 0.0015 18.5 2.2 0.0045 16.9 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KZN90489.1 - 0.0017 17.4 0.1 0.044 12.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KZN90489.1 - 0.0026 17.3 0.3 0.0066 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KZN90489.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KZN90489.1 - 0.039 14.1 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KZN90489.1 - 0.055 13.1 0.2 0.83 9.2 0.2 2.3 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KZN90489.1 - 0.073 12.9 0.5 0.56 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KZN90489.1 - 0.076 12.4 0.2 0.3 10.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KZN90489.1 - 0.13 12.3 0.0 0.87 9.6 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KZN90489.1 - 0.28 11.4 0.0 0.28 11.4 0.0 2.0 3 0 0 3 3 1 0 AAA domain Chromo PF00385.19 KZN90490.1 - 1e-07 31.5 0.7 2.4e-07 30.3 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 KZN90491.1 - 2.2e-54 183.2 0.3 2.7e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN90491.1 - 4.4e-13 49.7 0.0 6.7e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN90491.1 - 6.6e-10 38.4 0.1 8.7e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN90491.1 - 0.00017 21.0 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SpoIIID PF12116.3 KZN90491.1 - 0.074 12.9 0.1 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D Brix PF04427.13 KZN90492.1 - 1.2e-29 103.3 0.0 1.6e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain PfkB PF00294.19 KZN90493.1 - 5.5e-17 61.8 0.0 4.6e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HCV_NS5a_C PF12941.2 KZN90494.1 - 0.087 12.3 9.2 0.16 11.4 6.4 1.5 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region eIF-3_zeta PF05091.7 KZN90494.1 - 0.62 8.6 32.1 0.042 12.4 18.9 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.1 KZN90494.1 - 0.85 9.8 28.2 1.6 9.0 19.5 1.5 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KZN90494.1 - 3.9 6.4 29.3 5.9 5.8 20.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AUX_IAA PF02309.11 KZN90494.1 - 4.1 7.1 25.9 2.3 7.9 16.3 1.7 2 0 0 2 2 2 0 AUX/IAA family MMR1 PF08505.5 KZN90494.1 - 6.8 6.6 33.3 14 5.6 23.1 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.17 KZN90494.1 - 7.5 5.4 9.6 11 4.9 6.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 KZN90494.1 - 8.7 3.9 30.0 12 3.4 20.8 1.1 1 0 0 1 1 1 0 Ycf1 YjgP_YjgQ PF03739.9 KZN90494.1 - 9.7 4.8 10.0 13 4.3 6.9 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Abp2 PF09441.5 KZN90497.1 - 1.9e-82 275.4 0.0 3.2e-82 274.6 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.11 KZN90497.1 - 0.026 14.3 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Surfac_D-trimer PF09006.6 KZN90497.1 - 0.11 12.2 2.4 0.23 11.2 1.6 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation F-box-like PF12937.2 KZN90498.1 - 0.00056 19.5 1.4 0.0014 18.3 1.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2360 PF10152.4 KZN90498.1 - 2.2 8.5 7.0 2 8.6 0.9 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) LRR_7 PF13504.1 KZN90498.1 - 6.5 7.4 7.8 1.7 9.1 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat WW PF00397.21 KZN90499.1 - 0.00032 20.4 6.8 0.00073 19.3 3.1 2.7 2 0 0 2 2 2 1 WW domain Ribosomal_S30 PF04758.9 KZN90500.1 - 0.04 13.6 2.5 0.066 12.9 1.8 1.4 1 0 0 1 1 1 0 Ribosomal protein S30 ORC6 PF05460.8 KZN90501.1 - 0.13 11.3 5.3 0.15 11.1 3.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) OSR1_C PF12202.3 KZN90501.1 - 0.25 10.9 1.6 0.67 9.6 1.1 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal NumbF PF06311.7 KZN90502.1 - 0.063 13.3 0.3 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 NUMB domain Fungal_trans PF04082.13 KZN90504.1 - 6.3e-07 28.5 0.8 1.1e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KZN90504.1 - 1.6e-06 28.1 17.6 8.6e-05 22.6 0.3 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN90504.1 - 1.9e-05 24.6 16.1 3.6e-05 23.8 4.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KZN90504.1 - 0.0031 17.3 7.5 0.37 10.7 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KZN90504.1 - 0.023 14.9 19.6 0.14 12.5 0.4 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN90504.1 - 0.038 14.1 7.2 0.47 10.6 0.0 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Daxx PF03344.10 KZN90504.1 - 0.21 10.0 0.3 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Daxx Family zf-BED PF02892.10 KZN90504.1 - 3.1 7.6 8.6 1.5 8.6 3.2 2.4 1 1 1 2 2 2 0 BED zinc finger MFS_1 PF07690.11 KZN90505.1 - 9.8e-39 133.0 27.4 1.3e-38 132.6 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90505.1 - 1.1e-13 50.6 31.0 7.9e-13 47.7 5.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.8 KZN90505.1 - 8e-06 24.3 4.9 5e-05 21.7 1.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Gly-zipper_Omp PF13488.1 KZN90505.1 - 0.036 13.7 0.9 7.1 6.3 0.3 2.8 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KZN90505.1 - 1.1 8.8 5.0 15 5.1 3.5 2.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper FAA_hydrolase PF01557.13 KZN90506.1 - 1.1e-53 181.8 0.0 1.5e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family B12-binding PF02310.14 KZN90507.1 - 4.7e-05 23.2 0.1 6.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.13 KZN90507.1 - 0.00084 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family EHN PF06441.7 KZN90509.1 - 2e-36 124.3 1.8 6.7e-36 122.6 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KZN90509.1 - 5.8e-12 45.9 0.4 1.6e-11 44.5 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90509.1 - 4.9e-08 32.8 0.0 3.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN90510.1 - 4.7e-32 111.7 0.0 9e-32 110.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90510.1 - 8.4e-22 77.8 0.0 1.4e-21 77.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN90510.1 - 1.7e-17 63.5 0.0 5.8e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN90510.1 - 1.1e-10 41.4 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KZN90510.1 - 8.9e-08 31.9 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KZN90510.1 - 9.6e-07 29.2 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KZN90510.1 - 9.1e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 KZN90510.1 - 0.00072 18.4 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 KZN90510.1 - 0.00083 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 KZN90510.1 - 0.0019 16.7 0.0 0.0042 15.6 0.0 1.6 1 0 0 1 1 1 1 Ndr family Lipase_3 PF01764.20 KZN90510.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 KZN90510.1 - 0.0045 16.5 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase2 PF12740.2 KZN90510.1 - 0.0096 14.8 0.0 0.046 12.6 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF2048 PF09752.4 KZN90510.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2305 PF10230.4 KZN90510.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 KZN90510.1 - 0.033 13.4 0.0 1.6 7.9 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.3 KZN90510.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TBPIP PF07106.8 KZN90511.1 - 0.019 14.5 56.2 0.09 12.3 0.0 9.1 4 3 5 9 9 9 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KZN90511.1 - 0.08 12.7 44.9 0.03 14.1 2.1 8.1 4 4 2 8 8 8 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KZN90511.1 - 0.11 12.6 44.2 0.34 11.0 1.5 9.4 5 4 2 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 KZN90511.1 - 0.2 11.5 57.1 0.039 13.7 0.6 8.4 2 2 5 8 8 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KZN90511.1 - 0.23 11.7 55.6 3 8.1 0.9 11.1 7 5 2 9 9 9 0 Nucleopolyhedrovirus P10 protein Mit_KHE1 PF10173.4 KZN90511.1 - 0.28 11.0 4.1 0.23 11.2 0.5 2.7 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related FlaC_arch PF05377.6 KZN90511.1 - 0.5 10.3 0.0 0.5 10.3 0.0 9.6 11 1 0 11 11 11 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 KZN90511.1 - 0.64 8.4 60.9 0.31 9.4 6.2 5.0 2 1 2 5 5 5 0 AAA domain DUF3584 PF12128.3 KZN90511.1 - 0.68 7.1 67.1 0.029 11.7 15.6 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF3584) Hemerythrin PF01814.18 KZN90511.1 - 1 9.5 14.1 13 5.9 0.1 5.8 5 2 1 6 6 6 0 Hemerythrin HHE cation binding domain LPP PF04728.8 KZN90511.1 - 7.3 6.4 26.3 2.4 8.0 4.6 6.8 6 1 1 7 7 7 0 Lipoprotein leucine-zipper TIP49 PF06068.8 KZN90512.1 - 5.4e-173 575.2 5.0 6.3e-173 575.0 3.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KZN90512.1 - 3.3e-09 37.0 0.8 5.8e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KZN90512.1 - 5.7e-08 32.1 1.4 4.7e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KZN90512.1 - 6.3e-06 25.2 0.4 1.2e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KZN90512.1 - 4.8e-05 23.4 0.0 0.00069 19.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN90512.1 - 0.00013 22.1 0.0 0.12 12.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KZN90512.1 - 0.00094 18.3 0.7 0.0099 15.0 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KZN90512.1 - 0.0018 18.1 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KZN90512.1 - 0.0085 15.5 0.1 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KZN90512.1 - 0.01 15.3 0.0 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KZN90512.1 - 0.019 14.7 0.7 0.091 12.5 0.2 2.2 1 1 1 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 KZN90512.1 - 0.024 14.3 0.1 0.7 9.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 KZN90512.1 - 0.052 12.4 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KZN90512.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KZN90512.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 KZN90513.1 - 2.8e-14 52.4 0.5 5.8e-14 51.4 0.3 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 KZN90514.1 - 2.7e-75 251.3 0.0 3.4e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KZN90514.1 - 0.00091 18.8 0.0 0.011 15.4 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.9 KZN90515.1 - 2.8e-55 187.6 0.0 3.3e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.1 KZN90516.1 - 1.2e-157 525.5 0.1 1.5e-157 525.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RNA_pol_Rpb2_6 PF00562.23 KZN90517.1 - 5.1e-116 387.5 0.6 1.2e-115 386.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KZN90517.1 - 1.9e-53 180.4 0.6 1.9e-53 180.4 0.4 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KZN90517.1 - 1.2e-29 102.3 0.2 1.2e-28 99.2 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KZN90517.1 - 3.8e-29 101.4 3.6 7.5e-29 100.4 2.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KZN90517.1 - 1.1e-21 76.4 3.1 1.1e-21 76.3 0.5 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KZN90517.1 - 4.2e-20 71.2 0.2 3.1e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KZN90517.1 - 1.7e-14 53.5 0.6 3.4e-14 52.5 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 KZN90518.1 - 7.5e-61 198.3 10.8 2.4e-07 29.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.12 KZN90518.1 - 0.049 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 MgtE intracellular N domain ORC5_C PF14630.1 KZN90519.1 - 7.5e-93 310.9 0.0 9.6e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KZN90519.1 - 9.9e-15 55.0 0.2 3e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN90519.1 - 0.007 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KZN90519.1 - 0.026 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain E1-E2_ATPase PF00122.15 KZN90521.1 - 4.6e-60 202.5 7.3 4.6e-60 202.5 5.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KZN90521.1 - 4.3e-22 79.5 0.0 1.7e-21 77.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN90521.1 - 6.9e-14 52.4 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN90521.1 - 4.6e-10 38.8 0.0 1.6e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN90521.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2614 PF11023.3 KZN90521.1 - 6.3 6.6 6.4 0.99 9.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) 7tm_1 PF00001.16 KZN90523.1 - 5e-09 35.6 1.8 6.9e-09 35.2 1.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KZN90523.1 - 3e-08 33.4 11.6 9.5e-08 31.8 8.0 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 KZN90523.1 - 5.4e-08 32.0 5.6 5.4e-08 32.0 3.9 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KZN90523.1 - 1e-05 24.7 2.9 1.5e-05 24.2 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 KZN90523.1 - 0.0015 17.7 5.0 0.0022 17.1 3.5 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx gpUL132 PF11359.3 KZN90523.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 CFEM PF05730.6 KZN90524.1 - 7.6e-05 22.4 7.6 0.00013 21.6 5.3 1.5 1 1 0 1 1 1 1 CFEM domain EF-hand_4 PF12763.2 KZN90525.1 - 4.2e-36 122.8 0.0 3.9e-14 52.2 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KZN90525.1 - 6.9e-10 38.9 0.0 5.5e-06 26.4 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KZN90525.1 - 5e-06 25.4 0.1 0.0019 17.3 0.0 4.4 5 0 0 5 5 5 1 EF hand UBA PF00627.26 KZN90525.1 - 8.8e-06 25.4 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 KZN90525.1 - 3.8e-05 23.2 0.0 0.0059 16.1 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair Macoilin PF09726.4 KZN90525.1 - 0.00024 19.5 8.5 0.00024 19.5 5.9 1.6 2 0 0 2 2 2 1 Transmembrane protein GAS PF13851.1 KZN90525.1 - 0.00032 19.9 22.9 0.00083 18.6 7.4 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_6 PF13405.1 KZN90525.1 - 0.0017 18.0 0.9 1.7 8.7 0.0 5.0 5 0 0 5 5 5 1 EF-hand domain TPR_MLP1_2 PF07926.7 KZN90525.1 - 0.0023 17.7 28.8 0.03 14.0 12.5 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 KZN90525.1 - 0.0079 14.7 22.4 0.012 14.1 15.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3584 PF12128.3 KZN90525.1 - 0.029 11.7 25.0 0.041 11.2 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-hand_5 PF13202.1 KZN90525.1 - 0.059 12.7 0.5 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 EF hand Myosin_tail_1 PF01576.14 KZN90525.1 - 0.066 10.9 27.1 0.13 9.9 18.8 1.4 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 KZN90525.1 - 0.072 11.7 23.5 0.11 11.1 7.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KZN90525.1 - 0.086 12.4 25.7 0.016 14.8 9.5 2.2 1 1 1 2 2 2 0 IncA protein DUF812 PF05667.6 KZN90525.1 - 0.17 10.3 21.7 0.18 10.3 13.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) MAD PF05557.8 KZN90525.1 - 0.18 9.8 20.3 0.3 9.1 14.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.4 KZN90525.1 - 1.1 9.1 24.7 0.54 10.1 7.8 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KZN90525.1 - 1.5 8.7 11.1 1.9 8.3 2.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 KZN90525.1 - 1.6 7.8 9.7 0.83 8.7 2.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 KZN90525.1 - 3.7 7.4 30.6 1.4 8.8 9.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 KZN90525.1 - 3.8 6.9 21.7 2.9 7.2 7.4 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 KZN90525.1 - 6.1 6.5 22.7 8.6 6.1 2.8 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 KZN90525.1 - 7.2 5.5 26.3 1 8.3 14.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Mod_r PF07200.8 KZN90525.1 - 7.5 6.4 24.4 0.34 10.8 9.7 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tubulin PF00091.20 KZN90526.1 - 2.1e-69 233.6 0.0 3e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KZN90526.1 - 1.8e-48 163.7 0.0 3.2e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KZN90526.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.4 KZN90527.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator tRNA-synt_2 PF00152.15 KZN90528.1 - 4.8e-75 252.3 0.0 7.4e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 KZN90528.1 - 6.1e-17 61.3 0.0 8.5e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 KZN90528.1 - 0.0028 16.9 0.1 2.2 7.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KZN90528.1 - 0.0078 16.0 0.1 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.8 KZN90529.1 - 9.1e-43 146.2 0.0 1.2e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN90529.1 - 1.1e-07 30.9 0.4 3.2e-07 29.4 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KZN90529.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN90529.1 - 0.024 13.8 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KZN90529.1 - 0.1 12.0 0.0 0.42 10.0 0.0 1.8 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KZN90529.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) COesterase PF00135.23 KZN90530.1 - 6.6e-14 51.5 0.0 3.4e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family SKG6 PF08693.5 KZN90531.1 - 6.4e-06 25.3 0.0 6.4e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.7 KZN90531.1 - 0.0026 17.1 0.1 0.0065 15.9 0.0 1.6 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF2407_C PF13373.1 KZN90531.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain MIP PF00230.15 KZN90532.1 - 6e-46 156.7 10.3 7.6e-46 156.4 7.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 KZN90533.1 - 6.8e-37 126.9 42.2 2.2e-36 125.3 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90533.1 - 1.4e-13 50.2 16.9 1.4e-13 50.2 11.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KZN90533.1 - 4.3e-06 25.2 6.6 4.3e-06 25.2 4.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_transf_8 PF01501.15 KZN90534.1 - 3.2e-24 85.6 0.0 4.1e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KZN90534.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Gly_transf_sug PF04488.10 KZN90536.1 - 3.6e-07 30.5 0.0 7.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KZN90536.1 - 0.033 13.3 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RRN3 PF05327.6 KZN90537.1 - 2.8e-175 583.6 0.0 3.6e-175 583.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Fungal_trans PF04082.13 KZN90540.1 - 1.2e-18 66.9 0.5 2.2e-18 66.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRK PF00485.13 KZN90541.1 - 4.4e-06 26.3 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KZN90541.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KZN90541.1 - 0.00014 22.6 0.0 0.00073 20.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KZN90541.1 - 0.00033 19.8 0.0 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 KZN90541.1 - 0.00036 19.3 0.0 0.00059 18.6 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 KZN90541.1 - 0.00087 19.1 0.1 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KZN90541.1 - 0.0015 18.0 0.3 0.0054 16.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KZN90541.1 - 0.0033 17.7 0.0 0.011 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KZN90541.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 KZN90541.1 - 0.019 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 KZN90541.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KZN90541.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF4432 PF14486.1 KZN90541.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Torsin PF06309.6 KZN90541.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 KZN90541.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Tyr-DNA_phospho PF06087.7 KZN90542.1 - 5.5e-146 486.6 0.0 1.1e-145 485.6 0.0 1.4 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Iso_dh PF00180.15 KZN90542.1 - 4.8e-83 278.9 0.0 6.7e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PLDc_2 PF13091.1 KZN90542.1 - 0.069 12.9 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain ACBP PF00887.14 KZN90543.1 - 3.1e-13 49.1 0.4 4.9e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein MR_MLE_N PF02746.11 KZN90543.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UPF0149 PF03695.8 KZN90543.1 - 0.13 12.1 0.9 0.19 11.5 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) U-box PF04564.10 KZN90544.1 - 5e-20 71.2 0.0 9.5e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KZN90544.1 - 1.9e-14 53.0 2.9 1.6e-13 50.0 0.2 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KZN90544.1 - 9e-07 28.3 5.3 0.00035 20.2 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN90544.1 - 1.1e-05 24.8 5.8 5e-05 22.7 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KZN90544.1 - 2.7e-05 24.3 4.1 0.048 14.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN90544.1 - 6.1e-05 23.5 13.3 0.00075 20.0 0.1 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN90544.1 - 0.00093 19.4 2.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN90544.1 - 0.0056 16.7 0.7 1 9.6 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN90544.1 - 0.019 15.1 0.3 0.077 13.1 0.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Phasin_2 PF09361.5 KZN90544.1 - 0.13 12.3 5.5 0.54 10.3 2.8 2.4 2 0 0 2 2 2 0 Phasin protein GvpG PF05120.7 KZN90544.1 - 0.17 11.7 1.7 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G TPR_12 PF13424.1 KZN90544.1 - 0.34 10.8 3.9 9.3 6.2 0.3 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat LacAB_rpiB PF02502.13 KZN90545.1 - 6.8e-43 145.6 0.0 7.7e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.12 KZN90545.1 - 0.024 13.5 0.1 0.083 11.7 0.0 1.7 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) TIM PF00121.13 KZN90546.1 - 1.2e-45 155.5 0.0 1.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase IL13 PF03487.8 KZN90546.1 - 0.98 9.1 4.3 0.42 10.3 0.7 2.2 2 1 0 2 2 2 0 Interleukin-13 DHO_dh PF01180.16 KZN90547.1 - 2.2e-67 227.0 0.1 3.7e-55 186.9 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KZN90547.1 - 6.8e-07 28.4 0.0 4.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.12 KZN90547.1 - 4.9e-05 22.6 0.3 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 PcrB family IMPDH PF00478.20 KZN90547.1 - 0.068 12.0 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ADH_zinc_N PF00107.21 KZN90548.1 - 1.3e-26 92.6 0.3 1.9e-26 92.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN90548.1 - 1.2e-22 79.7 1.0 2e-22 79.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN90548.1 - 1.2e-11 45.5 0.1 2.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glucokinase PF02685.11 KZN90548.1 - 0.071 11.8 0.2 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Glucokinase Methyltransf_18 PF12847.2 KZN90548.1 - 0.08 13.5 0.2 1.1 9.8 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain Arf PF00025.16 KZN90549.1 - 1.5e-73 245.7 0.1 1.8e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KZN90549.1 - 2.9e-12 46.1 0.0 3.7e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KZN90549.1 - 3.9e-11 42.6 0.0 4.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KZN90549.1 - 9.2e-10 37.7 0.6 1.1e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KZN90549.1 - 5.3e-09 35.5 0.0 6.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN90549.1 - 1.1e-07 32.3 0.0 1.5e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN90549.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN90549.1 - 1.8e-05 24.2 0.0 0.0026 17.2 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KZN90549.1 - 0.0095 15.2 0.5 0.046 12.9 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 KZN90549.1 - 0.079 13.4 0.1 0.17 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 KZN90550.1 - 5.9e-31 107.2 0.0 1.1e-17 63.5 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KZN90550.1 - 2.5e-05 23.0 0.0 0.002 16.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 KZN90550.1 - 0.12 10.6 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Paf1 PF03985.8 KZN90551.1 - 1.8e-38 132.4 0.6 1.2e-26 93.4 0.0 3.0 2 1 0 2 2 2 2 Paf1 APH PF01636.18 KZN90552.1 - 7.9e-17 61.7 0.0 1.2e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN90552.1 - 0.017 14.3 0.0 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 KZN90552.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 KZN90553.1 - 7.1e-13 48.8 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN90553.1 - 0.024 13.2 0.0 0.57 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF3419 PF11899.3 KZN90554.1 - 1.3e-155 517.8 0.0 1.8e-155 517.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KZN90554.1 - 6.8e-12 45.3 0.0 2e-09 37.3 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90554.1 - 6.2e-11 42.1 0.0 6.1e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN90554.1 - 4.3e-10 40.1 0.0 4.1e-09 37.0 0.0 2.6 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN90554.1 - 8e-10 39.0 0.0 3e-09 37.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN90554.1 - 6.2e-07 29.7 0.0 4.4e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN90554.1 - 7.9e-07 29.4 0.0 9.6e-05 22.7 0.0 3.1 3 1 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN90554.1 - 1.3e-06 27.7 0.0 2.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KZN90554.1 - 1.9e-06 27.9 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KZN90554.1 - 0.00032 20.2 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KZN90554.1 - 0.00036 20.2 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN90554.1 - 0.028 13.4 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_28 PF02636.12 KZN90554.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KZN90554.1 - 0.048 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ctr PF04145.10 KZN90556.1 - 1.1e-30 106.5 0.5 3.6e-30 104.9 0.3 1.7 1 1 0 1 1 1 1 Ctr copper transporter family Rer1 PF03248.8 KZN90557.1 - 7.8e-83 276.3 3.0 8.7e-83 276.2 2.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.6 KZN90557.1 - 0.31 10.9 4.9 2.7 7.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF962) ECH PF00378.15 KZN90558.1 - 1.8e-72 243.4 0.0 2.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KZN90558.1 - 0.003 17.6 0.1 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Sugar_tr PF00083.19 KZN90559.1 - 3.8e-82 276.2 20.1 4.4e-82 276.0 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN90559.1 - 1.8e-16 59.8 24.3 4.1e-14 52.0 11.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Catalase PF00199.14 KZN90561.1 - 4.6e-186 618.0 1.4 5.5e-186 617.8 1.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN90561.1 - 8e-12 44.8 0.1 2.5e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Lipase_3 PF01764.20 KZN90562.1 - 1.1e-06 28.3 0.0 5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) VPS9 PF02204.13 KZN90563.1 - 2.1e-26 91.9 0.1 4.1e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ECM11 PF15463.1 KZN90564.1 - 5.8e-46 156.2 0.0 5.8e-46 156.2 0.0 2.9 3 1 0 3 3 3 1 Extracellular mutant protein 11 APH PF01636.18 KZN90565.1 - 9.2e-18 64.8 0.0 2.5e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_I_TF PF04090.7 KZN90566.1 - 1.5e-11 43.9 0.0 2.1e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor zf-RING_2 PF13639.1 KZN90567.1 - 1.4e-15 56.8 4.6 2.2e-15 56.1 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN90567.1 - 7.6e-11 41.9 0.8 1.4e-10 41.1 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN90567.1 - 6.4e-08 32.1 3.5 9.8e-08 31.5 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN90567.1 - 1.7e-07 31.1 4.1 2.9e-07 30.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN90567.1 - 3.1e-06 26.9 0.4 6e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KZN90567.1 - 8.4e-06 25.4 2.8 1.3e-05 24.8 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN90567.1 - 4.4e-05 23.0 1.4 7.4e-05 22.3 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KZN90567.1 - 0.00076 19.4 5.2 0.0012 18.8 3.6 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 KZN90567.1 - 0.0066 15.9 1.0 0.013 15.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KZN90567.1 - 0.039 13.9 1.7 0.068 13.1 1.2 1.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 KZN90567.1 - 0.041 13.8 2.9 0.074 13.0 2.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 KZN90567.1 - 0.059 13.1 1.5 0.11 12.2 1.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KZN90567.1 - 0.075 12.7 2.0 0.16 11.6 1.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KZN90567.1 - 0.15 11.6 3.3 0.24 11.0 2.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Formyl_trans_N PF00551.14 KZN90568.1 - 6.2e-39 133.4 0.1 7.3e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Fungal_trans_2 PF11951.3 KZN90569.1 - 2.4e-12 46.1 0.7 4.5e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90569.1 - 3.8e-07 29.8 8.5 6.4e-07 29.1 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1387 PF07139.6 KZN90569.1 - 1.4 8.4 9.5 2.2 7.8 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DEAD PF00270.24 KZN90570.1 - 3.6e-23 81.8 0.0 6.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90570.1 - 1.8e-11 43.7 0.0 4.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KZN90570.1 - 8.1e-10 39.1 0.3 1.1e-08 35.5 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 KZN90570.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.10 KZN90570.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Neur PF00064.13 KZN90570.1 - 1.1 7.3 2.7 1.7 6.6 1.9 1.2 1 0 0 1 1 1 0 Neuraminidase Peptidase_S10 PF00450.17 KZN90571.1 - 8.8e-89 298.5 1.1 1e-88 298.2 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ran_BP1 PF00638.13 KZN90572.1 - 5.5e-18 65.1 0.1 8.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Yip1 PF04893.12 KZN90573.1 - 1.2e-12 47.6 14.9 2e-12 46.9 10.3 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 KZN90573.1 - 1.1 8.8 9.9 2 8.0 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) TraG_N PF07916.6 KZN90573.1 - 2.6 6.3 4.8 5 5.4 3.3 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region 7TM_transglut PF14402.1 KZN90573.1 - 6.4 5.5 9.3 8.3 5.2 6.4 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Bac_luciferase PF00296.15 KZN90574.1 - 7.7e-63 212.4 0.1 1.1e-62 211.9 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PPR_2 PF13041.1 KZN90575.1 - 2e-22 78.8 0.0 1.6e-15 56.8 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KZN90575.1 - 1.8e-07 30.8 0.5 0.021 15.1 0.0 5.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 KZN90575.1 - 4.8e-05 23.0 0.1 0.12 12.3 0.0 4.0 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 KZN90575.1 - 0.054 12.9 0.4 17 4.9 0.0 3.5 4 0 0 4 4 4 0 PPR repeat APC_CDC26 PF10471.4 KZN90576.1 - 4.4 8.1 9.4 0.26 12.0 1.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3987 PF13148.1 KZN90576.1 - 6.3 5.2 8.8 10 4.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Lipase_GDSL PF00657.17 KZN90577.1 - 1e-07 32.0 1.1 2.5e-07 30.7 0.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KZN90577.1 - 0.0003 20.9 1.2 0.00055 20.1 0.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DEAD PF00270.24 KZN90578.1 - 1.2e-45 155.0 0.0 9.5e-44 148.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90578.1 - 1.1e-27 95.7 0.0 2.6e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN90578.1 - 0.0021 17.8 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KZN90578.1 - 0.0074 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KZN90578.1 - 0.058 11.8 0.0 1.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 KZN90578.1 - 0.081 13.0 0.5 2.6 8.2 0.1 3.0 1 1 1 2 2 2 0 AAA domain DUF2443 PF10398.4 KZN90578.1 - 0.081 12.7 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Phos_pyr_kin PF08543.7 KZN90579.1 - 1.5e-81 273.1 0.4 2.1e-81 272.7 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KZN90579.1 - 2.7e-51 174.3 0.3 3.5e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KZN90579.1 - 2.5e-07 30.1 0.1 3.8e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 KZN90579.1 - 4.4e-05 22.8 1.5 0.00011 21.5 0.3 2.0 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.10 KZN90579.1 - 0.002 17.3 0.8 0.06 12.5 0.1 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family DNA_pol_B PF00136.16 KZN90580.1 - 2.3e-115 386.0 3.4 3.8e-115 385.3 2.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KZN90580.1 - 2.8e-67 225.7 1.0 5.8e-67 224.7 0.7 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KZN90580.1 - 3e-39 134.7 0.0 1.2e-38 132.8 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KZN90580.1 - 1.2e-23 82.7 8.2 1.2e-23 82.7 5.7 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DUF4451 PF14616.1 KZN90580.1 - 0.0083 15.8 1.7 0.02 14.6 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Ribosomal_S9 PF00380.14 KZN90581.1 - 6.1e-40 136.2 1.2 6.9e-40 136.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 KZN90582.1 - 4.5e-42 143.1 0.0 5.8e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 KZN90583.1 - 3.2e-84 279.9 1.1 1.1e-47 161.6 0.4 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KZN90583.1 - 0.0037 16.9 0.3 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Plasmid recombination enzyme MFS_1 PF07690.11 KZN90584.1 - 5e-42 143.8 53.4 7.7e-36 123.5 21.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF843 PF05814.6 KZN90584.1 - 0.16 11.7 0.6 0.68 9.7 0.1 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) MFS_3 PF05977.8 KZN90584.1 - 8.7 4.3 18.3 1.1 7.3 8.6 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector PAD_porph PF04371.10 KZN90585.1 - 7.2e-70 235.6 0.0 2.9e-68 230.3 0.0 2.0 1 1 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase SelP_N PF04592.9 KZN90586.1 - 0.011 15.1 17.7 0.011 15.1 12.2 1.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.17 KZN90586.1 - 0.13 11.2 8.1 0.15 11.0 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4551 PF15087.1 KZN90586.1 - 0.38 9.0 6.4 0.45 8.8 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.4 KZN90586.1 - 0.68 8.1 11.5 0.77 7.9 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 KZN90586.1 - 0.73 7.9 3.7 0.85 7.7 2.6 1.1 1 0 0 1 1 1 0 Menin RCR PF12273.3 KZN90586.1 - 6.9 7.2 8.5 11 6.6 5.9 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Presenilin PF01080.12 KZN90586.1 - 7 5.3 5.6 7.7 5.2 3.9 1.1 1 0 0 1 1 1 0 Presenilin zf-H2C2_2 PF13465.1 KZN90587.1 - 3.5e-07 30.2 12.4 9.8e-06 25.6 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN90587.1 - 2.7e-06 27.3 13.9 0.00019 21.5 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KZN90587.1 - 0.00038 20.5 3.9 0.00068 19.7 2.7 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KZN90587.1 - 0.0036 17.5 16.8 0.018 15.3 4.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KZN90587.1 - 0.0042 17.1 4.7 0.058 13.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 KZN90587.1 - 0.17 11.7 1.4 0.28 11.0 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 KZN90587.1 - 0.51 10.1 8.4 0.25 11.1 0.9 2.3 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 KZN90587.1 - 0.63 10.3 5.3 1.8 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KZN90587.1 - 6.1 6.6 8.4 8.8 6.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AA_permease_2 PF13520.1 KZN90588.1 - 4.9e-63 213.1 44.9 5.9e-63 212.8 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN90588.1 - 8.6e-18 63.9 33.2 1.2e-17 63.4 23.0 1.2 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.4 KZN90589.1 - 4e-24 84.0 0.0 5.6e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Thioredoxin PF00085.15 KZN90590.1 - 3.5e-38 129.4 0.0 3.9e-24 84.3 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KZN90590.1 - 9e-14 51.6 0.0 4.7e-06 26.5 0.0 4.3 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KZN90590.1 - 2.2e-07 31.0 0.3 0.015 15.4 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KZN90590.1 - 2.1e-05 24.5 0.1 0.019 15.0 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KZN90590.1 - 0.00039 20.3 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 KZN90590.1 - 0.00041 20.0 0.7 1.1 8.9 0.0 3.4 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_3 PF13192.1 KZN90590.1 - 0.0035 17.1 0.1 0.52 10.1 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KZN90590.1 - 0.017 15.1 0.7 0.13 12.3 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin-like ETC_C1_NDUFA5 PF04716.9 KZN90591.1 - 1.9e-22 78.5 2.0 3e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF3121 PF11319.3 KZN90591.1 - 0.066 12.7 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Coatomer_WDAD PF04053.9 KZN90592.1 - 1.5e-167 557.9 0.0 5.1e-167 556.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 KZN90592.1 - 1.8e-47 157.5 8.2 2.1e-10 40.0 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KZN90592.1 - 6.5e-05 21.2 0.1 0.063 11.3 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KZN90592.1 - 0.0033 17.1 0.0 2.5 7.9 0.0 3.7 1 1 3 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 KZN90593.1 - 6e-71 238.6 0.0 7.7e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90593.1 - 7.7e-32 110.3 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KZN90593.1 - 6.3e-09 36.2 0.2 6.3e-09 36.2 0.1 2.4 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 KZN90593.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RNA_pol_A_bac PF01000.21 KZN90593.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain SWIRM PF04433.12 KZN90594.1 - 2.5e-14 53.1 0.0 6.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KZN90594.1 - 2.2e-11 43.0 4.4 3.8e-11 42.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KZN90594.1 - 2.1e-08 34.0 0.0 5.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ECH PF00378.15 KZN90595.1 - 4.3e-46 157.0 0.1 5.4e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 KZN90595.1 - 0.079 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 TQO small subunit DoxD Mannitol_dh_C PF08125.8 KZN90596.1 - 4e-47 160.4 0.0 6.1e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KZN90596.1 - 2.9e-18 66.2 1.1 3.9e-18 65.8 0.2 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 KZN90596.1 - 0.0081 15.8 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KZN90596.1 - 0.048 13.0 1.1 0.14 11.5 0.8 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain B12-binding PF02310.14 KZN90596.1 - 0.079 12.8 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain SUR7 PF06687.7 KZN90597.1 - 8.4e-22 77.7 4.7 1.1e-21 77.4 3.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Mtp PF03821.11 KZN90597.1 - 0.12 11.7 0.1 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Fig1 PF12351.3 KZN90597.1 - 2.1 8.2 12.2 1.6 8.5 5.5 2.4 2 1 1 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4282 PF14110.1 KZN90597.1 - 4.3 7.5 13.4 0.19 11.9 3.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) APH PF01636.18 KZN90598.1 - 1.5e-13 51.0 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN90598.1 - 0.017 13.7 0.0 3.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 KZN90598.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase LOH1CR12 PF10158.4 KZN90598.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Sugar_tr PF00083.19 KZN90599.1 - 2.5e-22 79.1 25.1 3.1e-20 72.1 17.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter RCC1 PF00415.13 KZN90600.1 - 3.2e-37 126.4 7.0 1.7e-08 34.5 0.0 7.2 6 2 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KZN90600.1 - 1.9e-24 84.6 23.3 1.5e-07 30.7 0.3 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 KZN90601.1 - 3.6e-58 196.6 1.5 4.2e-58 196.4 1.0 1.0 1 0 0 1 1 1 1 Rad9 Glyco_transf_54 PF04666.8 KZN90602.1 - 2e-14 53.0 0.0 4e-11 42.2 0.0 3.0 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF3405 PF11885.3 KZN90603.1 - 1.3e-143 478.8 11.1 2.5e-143 477.9 7.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_transf_54 PF04666.8 KZN90604.1 - 1.5e-09 37.0 0.0 1.2e-07 30.7 0.0 2.8 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Nuc_sug_transp PF04142.10 KZN90604.1 - 0.038 13.0 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter Glyco_transf_25 PF01755.12 KZN90604.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) LON PF02190.11 KZN90605.1 - 6.5e-26 91.2 0.0 9.9e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KZN90605.1 - 3.2e-12 46.2 18.2 2.4e-08 33.8 6.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN90605.1 - 1.5e-11 43.9 18.6 3.3e-08 33.2 7.1 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KZN90605.1 - 5e-11 42.1 16.5 4.9e-07 29.3 5.4 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN90605.1 - 2.3e-10 39.9 14.9 1.1e-08 34.6 4.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KZN90605.1 - 3.7e-10 39.5 15.6 3e-06 27.0 4.7 3.0 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KZN90605.1 - 1e-09 37.8 15.3 2.6e-07 30.1 6.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN90605.1 - 1.3e-07 31.1 14.6 3.6e-05 23.3 1.8 3.3 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_4 PF14570.1 KZN90605.1 - 0.00017 21.0 7.4 0.0065 16.0 3.8 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.10 KZN90605.1 - 0.0024 17.7 0.1 0.0083 16.0 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-rbx1 PF12678.2 KZN90605.1 - 0.0067 16.5 3.9 0.021 14.9 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KZN90605.1 - 0.045 13.2 9.6 1.1 8.9 2.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KZN90605.1 - 0.11 12.3 2.0 1.1 9.1 1.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KZN90605.1 - 7.7 6.0 15.6 0.023 14.1 3.4 2.4 2 1 0 2 2 2 0 P-11 zinc finger DAO PF01266.19 KZN90606.1 - 1.7e-43 148.9 0.2 2.1e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 KZN90606.1 - 2.3e-13 49.5 0.1 5.9e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 KZN90606.1 - 5.2e-08 32.8 0.6 1.7e-07 31.1 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN90606.1 - 4.5e-06 25.9 0.0 7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KZN90606.1 - 6.2e-06 25.5 0.8 0.0011 18.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN90606.1 - 9.4e-06 24.7 0.4 1.9e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 KZN90606.1 - 2.1e-05 23.7 0.1 3.2e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN90606.1 - 4.7e-05 23.3 0.1 0.00019 21.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN90606.1 - 0.00044 19.2 0.2 0.001 18.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KZN90606.1 - 0.0015 18.9 0.3 0.0033 17.7 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN90606.1 - 0.0019 17.1 0.3 0.0077 15.1 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KZN90606.1 - 0.0032 17.5 0.3 0.051 13.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KZN90606.1 - 0.0045 16.1 0.2 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KZN90606.1 - 0.0051 16.4 0.1 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KZN90606.1 - 0.01 15.6 0.3 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KZN90606.1 - 0.023 13.1 0.1 0.036 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Amidohydro_4 PF13147.1 KZN90607.1 - 1.4e-25 90.9 0.0 1.8e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN90607.1 - 3.3e-14 53.2 0.0 2.3e-08 34.0 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KZN90607.1 - 2.7e-13 49.5 1.4 3.9e-13 49.0 0.3 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN90607.1 - 2e-06 27.3 0.0 0.019 14.2 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.13 KZN90608.1 - 5.6e-07 29.3 10.8 1e-06 28.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RICTOR_N PF14664.1 KZN90609.1 - 8.2e-133 442.5 1.3 1.3e-132 441.8 0.9 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KZN90609.1 - 8e-89 296.5 0.3 2.3e-86 288.4 0.3 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KZN90609.1 - 2.6e-43 146.6 0.0 9.4e-42 141.5 0.0 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KZN90609.1 - 2.9e-25 88.0 1.7 1.2e-24 85.9 0.2 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KZN90609.1 - 8.5e-10 38.2 3.4 1.7e-09 37.2 2.4 1.5 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 KZN90609.1 - 0.014 15.4 3.1 0.034 14.1 2.2 1.6 1 0 0 1 1 1 0 Up-regulated During Septation PsiA PF06952.6 KZN90609.1 - 0.052 12.6 0.1 0.089 11.8 0.1 1.3 1 0 0 1 1 1 0 PsiA protein PDH PF02153.12 KZN90610.1 - 4.1e-09 35.7 0.0 5.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KZN90610.1 - 1.1e-06 28.5 0.0 4e-06 26.7 0.0 1.9 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN90610.1 - 1.8e-06 28.2 0.0 3.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KZN90610.1 - 0.00034 20.0 0.0 0.00077 18.9 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KZN90610.1 - 0.00064 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KZN90610.1 - 0.0094 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KZN90610.1 - 0.059 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KZN90610.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S11 PF00411.14 KZN90611.1 - 2e-40 137.3 0.4 2.6e-40 137.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 AAR2 PF05282.6 KZN90612.1 - 4e-95 318.8 0.0 4.7e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Aminotran_4 PF01063.14 KZN90613.1 - 4.2e-24 85.3 0.0 8.9e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class IV Fungal_trans PF04082.13 KZN90614.1 - 1.8e-20 72.9 0.6 3e-20 72.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90614.1 - 1.3e-05 25.0 10.0 2.8e-05 23.9 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Paf67 PF10255.4 KZN90615.1 - 6.2e-155 516.0 0.0 7.2e-155 515.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KZN90615.1 - 0.07 13.0 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 KZN90616.1 - 2.7e-127 425.2 10.3 3.3e-127 424.9 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KZN90616.1 - 4.2e-16 59.2 0.9 4.2e-16 59.2 0.6 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KZN90616.1 - 5.1e-15 55.5 0.5 9.5e-09 35.4 0.0 4.6 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 KZN90616.1 - 3.1e-10 39.2 4.1 0.0015 18.4 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.4 KZN90616.1 - 2.1e-06 27.4 0.3 2 8.1 0.0 3.9 3 1 0 3 3 3 3 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KZN90616.1 - 0.00062 19.1 2.1 2.4 7.4 0.0 3.7 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KZN90616.1 - 0.0017 18.7 8.9 0.98 9.9 0.0 6.3 6 1 1 7 7 7 2 HEAT-like repeat DNA_alkylation PF08713.6 KZN90616.1 - 0.047 13.2 0.1 0.43 10.0 0.0 2.4 2 1 1 3 3 3 0 DNA alkylation repair enzyme Arm PF00514.18 KZN90616.1 - 0.25 11.2 6.7 3.4 7.6 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF1077 PF06417.7 KZN90617.1 - 4.1e-51 171.5 2.2 5.5e-51 171.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.1 KZN90617.1 - 0.05 12.4 2.2 0.052 12.3 0.5 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 Rubella_Capsid PF05750.6 KZN90617.1 - 7.4 5.8 10.0 12 5.2 7.0 1.3 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.11 KZN90618.1 - 1.4e-52 178.5 18.9 1.4e-52 178.5 13.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90618.1 - 1.2e-11 43.9 11.7 1.2e-11 43.9 8.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF791 PF05631.9 KZN90618.1 - 0.00027 19.7 3.4 0.00048 18.9 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) DUF3353 PF11833.3 KZN90618.1 - 0.26 10.7 4.7 0.73 9.2 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) MFS_3 PF05977.8 KZN90618.1 - 0.47 8.4 12.7 0.048 11.7 3.5 2.6 3 0 0 3 3 3 0 Transmembrane secretion effector Aminotran_5 PF00266.14 KZN90619.1 - 2.4e-14 52.8 0.0 8.6e-14 51.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KZN90619.1 - 0.0044 16.1 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KZN90619.1 - 0.0048 15.2 0.0 0.0074 14.6 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KZN90619.1 - 0.0065 15.0 0.1 0.013 14.0 0.1 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cleaved_Adhesin PF07675.6 KZN90619.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain Fe-S_biosyn PF01521.15 KZN90620.1 - 4.3e-11 42.7 0.0 1.2e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.20 KZN90621.1 - 4.7e-34 117.7 0.0 6.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90621.1 - 2.4e-09 36.6 0.0 0.00021 20.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Zn_clus PF00172.13 KZN90622.1 - 1.5e-08 34.3 11.1 2.9e-08 33.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN90622.1 - 1.9e-05 23.4 0.2 3.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adeno_E1A PF02703.9 KZN90622.1 - 5.2 6.4 6.1 9.8 5.5 4.2 1.3 1 0 0 1 1 1 0 Early E1A protein Peroxidase_2 PF01328.12 KZN90623.1 - 4.1e-35 120.9 0.2 4.8e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 TFIID-18kDa PF02269.11 KZN90623.1 - 0.023 14.5 0.0 0.97 9.2 0.0 2.5 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit CWC25 PF12542.3 KZN90624.1 - 8.6e-23 80.6 0.1 8.6e-23 80.6 0.1 3.8 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KZN90624.1 - 1.6e-14 53.6 9.9 1.6e-14 53.6 6.9 4.8 4 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR FAT PF02259.18 KZN90625.1 - 1.2e-127 425.7 0.2 1.2e-127 425.7 0.1 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KZN90625.1 - 2.4e-60 203.0 1.1 4.1e-57 192.5 0.6 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KZN90625.1 - 4e-58 196.6 0.2 9e-58 195.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KZN90625.1 - 1.8e-40 137.0 3.4 4e-40 135.9 0.1 3.4 2 1 1 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 KZN90625.1 - 1e-16 60.9 9.2 0.0028 17.9 0.0 8.8 7 2 2 9 9 9 5 HEAT repeats FATC PF02260.15 KZN90625.1 - 2.7e-16 58.6 0.7 6.4e-16 57.4 0.5 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 KZN90625.1 - 5.5e-14 52.1 8.3 0.0051 17.2 0.0 10.7 10 2 4 14 14 14 3 HEAT-like repeat HEAT PF02985.17 KZN90625.1 - 1.3e-10 40.3 19.8 0.16 12.1 0.0 11.3 13 0 0 13 13 13 3 HEAT repeat CLASP_N PF12348.3 KZN90625.1 - 0.0016 17.8 1.4 0.94 8.7 0.0 4.8 6 0 0 6 6 6 1 CLASP N terminal Epimerase PF01370.16 KZN90626.1 - 1.6e-18 67.0 0.0 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN90626.1 - 5.5e-15 54.8 0.0 7.1e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN90626.1 - 7.9e-10 38.0 0.0 3.2e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KZN90626.1 - 5.2e-09 36.3 0.0 1e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN90626.1 - 1.5e-06 28.2 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN90626.1 - 0.00013 21.0 0.0 0.00019 20.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KZN90626.1 - 0.00031 20.4 0.0 0.00067 19.3 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KZN90626.1 - 0.00039 19.7 0.4 0.0026 17.0 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 KZN90626.1 - 0.0015 17.6 0.2 0.02 13.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KZN90626.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mit_ribos_Mrp51 PF11709.3 KZN90627.1 - 6.2e-99 331.1 0.1 7.3e-99 330.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 KZN90628.1 - 3.4e-59 197.9 1.0 4.2e-59 197.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KZN90628.1 - 0.045 14.4 0.2 0.073 13.7 0.1 1.4 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 KZN90629.1 - 7.2e-15 54.8 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF1749 PF08538.5 KZN90632.1 - 1e-97 326.7 0.0 1.1e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KZN90632.1 - 6.1e-08 32.8 0.0 8.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN90632.1 - 2.7e-07 30.4 0.1 8.9e-07 28.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN90632.1 - 0.00023 20.8 0.1 0.046 13.2 0.0 3.0 1 1 1 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 KZN90632.1 - 0.005 16.2 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 KZN90632.1 - 0.023 14.2 0.4 0.058 12.9 0.1 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.23 KZN90633.1 - 2e-83 280.1 0.0 7.9e-78 261.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KZN90633.1 - 8.8e-69 231.6 0.1 2.3e-33 115.3 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KZN90633.1 - 3.6e-27 94.4 0.4 2.3e-12 46.9 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN90633.1 - 7e-09 36.5 0.2 0.0023 18.8 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KZN90633.1 - 0.018 13.6 0.2 4.3 5.7 0.1 2.4 2 0 0 2 2 2 0 Alcohol acetyltransferase ABC_membrane PF00664.18 KZN90634.1 - 1.3e-77 260.9 30.5 6e-46 157.0 5.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN90634.1 - 1.9e-62 209.5 0.0 6.6e-31 107.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN90634.1 - 4.8e-17 61.9 0.7 8.1e-06 25.2 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KZN90634.1 - 2.6e-09 36.4 0.2 0.0012 18.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KZN90634.1 - 7.2e-09 36.0 0.0 0.035 14.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KZN90634.1 - 1e-08 35.4 2.4 0.001 19.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KZN90634.1 - 4.1e-07 30.8 0.0 0.056 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KZN90634.1 - 1.2e-06 28.6 2.2 0.56 10.3 0.0 4.4 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KZN90634.1 - 3.3e-06 26.3 0.0 0.018 14.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KZN90634.1 - 5.6e-06 25.8 0.6 0.38 10.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain ABC_ATPase PF09818.4 KZN90634.1 - 6.7e-06 24.9 1.1 0.0034 16.0 0.0 2.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class APS_kinase PF01583.15 KZN90634.1 - 9.2e-06 25.3 0.2 0.0051 16.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF87 PF01935.12 KZN90634.1 - 1.2e-05 25.2 0.3 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_30 PF13604.1 KZN90634.1 - 1.4e-05 24.7 1.6 0.34 10.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KZN90634.1 - 2e-05 25.0 0.2 0.19 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KZN90634.1 - 9.5e-05 22.0 0.2 0.25 11.0 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KZN90634.1 - 0.00043 20.4 1.0 9 6.5 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN90634.1 - 0.00058 19.7 0.2 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KZN90634.1 - 0.00067 18.8 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KZN90634.1 - 0.00072 19.8 0.1 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KZN90634.1 - 0.0011 18.7 0.0 2.3 7.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 KZN90634.1 - 0.0011 18.8 0.2 3.1 7.7 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KZN90634.1 - 0.002 17.6 3.6 0.29 10.5 0.1 3.4 2 1 1 3 3 3 1 AAA-like domain AAA_14 PF13173.1 KZN90634.1 - 0.0043 16.9 0.0 3.7 7.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KZN90634.1 - 0.0066 15.9 0.0 0.14 11.5 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KZN90634.1 - 0.01 15.7 0.0 3.6 7.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 KZN90634.1 - 0.023 14.4 0.2 8.6 6.0 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KZN90634.1 - 0.047 13.1 0.9 8.2 5.8 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain KdpD PF02702.12 KZN90634.1 - 0.083 12.0 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain NB-ARC PF00931.17 KZN90634.1 - 0.18 10.6 0.3 12 4.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Acetyltransf_8 PF13523.1 KZN90635.1 - 2.1e-33 115.3 0.4 3.2e-33 114.7 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 KZN90636.1 - 8.6e-47 159.3 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DoxD PF04173.8 KZN90636.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.11 KZN90637.1 - 2.4e-20 72.5 45.8 2.4e-20 72.5 31.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KZN90638.1 - 5.4e-49 166.5 0.0 6.7e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF706 PF05153.10 KZN90639.1 - 6e-128 425.4 3.0 8e-128 425.0 2.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KZN90639.1 - 0.16 11.9 3.3 0.42 10.6 0.0 2.8 3 1 0 3 3 3 0 HD domain GFO_IDH_MocA PF01408.17 KZN90640.1 - 2e-24 86.3 0.1 3.7e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN90640.1 - 3.5e-05 23.5 0.0 8.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 KZN90640.1 - 0.042 13.6 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_C13 PF01650.13 KZN90642.1 - 2.5e-08 33.5 0.0 3.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Glyco_hydro_28 PF00295.12 KZN90643.1 - 2.5e-114 381.6 17.0 2.8e-114 381.4 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KZN90643.1 - 0.0069 16.1 27.6 0.019 14.7 17.8 2.6 1 1 2 3 3 3 1 Right handed beta helix region NAD_binding_10 PF13460.1 KZN90644.1 - 4.1e-16 59.5 0.0 8.3e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN90644.1 - 4.6e-07 29.5 0.0 7.6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KZN90644.1 - 0.037 12.9 0.0 0.066 12.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain AMP-binding PF00501.23 KZN90645.1 - 1.1e-91 307.3 0.0 1.3e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN90645.1 - 3.4e-11 43.9 0.0 8.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S19 PF00203.16 KZN90646.1 - 9.6e-34 114.8 0.3 1.5e-33 114.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 KZN90647.1 - 1.2e-27 96.0 12.7 1.4e-27 95.8 8.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KZN90647.1 - 0.16 10.1 1.5 0.16 10.1 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SPT2 PF08243.6 KZN90648.1 - 3.8e-05 23.9 13.1 3.8e-05 23.9 9.0 2.0 2 1 0 2 2 2 1 SPT2 chromatin protein Glyco_hydro_52 PF03512.8 KZN90648.1 - 0.02 13.5 0.4 0.026 13.1 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Carb_kinase PF01256.12 KZN90649.1 - 3.9e-42 144.1 0.1 8.1e-41 139.9 0.1 2.1 1 1 0 1 1 1 1 Carbohydrate kinase EGF_CA PF07645.10 KZN90650.1 - 8.7e-06 25.6 5.9 8.7e-06 25.6 4.1 2.2 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 KZN90650.1 - 1.1e-05 25.2 5.4 1.1e-05 25.2 3.8 2.4 3 1 0 3 3 3 1 EGF domain cEGF PF12662.2 KZN90650.1 - 0.003 17.1 0.1 0.003 17.1 0.1 2.6 4 0 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KZN90650.1 - 0.0038 17.3 5.2 0.0038 17.3 3.6 2.5 2 2 0 2 2 2 1 Coagulation Factor Xa inhibitory site MCM PF00493.18 KZN90651.1 - 3.9e-134 446.6 0.1 3.4e-133 443.5 0.0 2.0 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KZN90651.1 - 5.7e-29 101.0 0.4 2.3e-28 99.1 0.1 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN90651.1 - 3.3e-07 29.6 0.0 2.4e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN90651.1 - 1.9e-06 27.6 0.0 4.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KZN90651.1 - 0.028 14.0 0.1 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KZN90651.1 - 0.11 11.9 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 KZN90652.1 - 1.8e-53 180.2 0.0 2.4e-43 147.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KZN90652.1 - 1.7e-29 101.6 0.4 4e-29 100.4 0.3 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KZN90652.1 - 1.4e-10 41.5 3.0 5.5e-06 26.4 0.1 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 KZN90652.1 - 1.1e-06 28.3 0.1 0.0019 17.9 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_2 PF07724.9 KZN90652.1 - 1.5e-06 28.2 0.0 0.084 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KZN90652.1 - 3.8e-06 26.6 0.4 0.029 14.0 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 KZN90652.1 - 4.3e-06 27.5 0.0 0.18 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KZN90652.1 - 1.2e-05 24.7 0.2 0.024 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 KZN90652.1 - 2.6e-05 24.3 0.2 0.35 11.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN90652.1 - 7.1e-05 23.1 0.7 0.06 13.6 0.2 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KZN90652.1 - 8.3e-05 21.7 0.0 0.007 15.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KZN90652.1 - 9.7e-05 21.5 0.0 0.44 9.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 KZN90652.1 - 0.00045 20.1 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KZN90652.1 - 0.0011 18.7 0.1 0.87 9.3 0.0 3.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KZN90652.1 - 0.0018 18.2 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KZN90652.1 - 0.002 17.5 0.5 3.6 6.9 0.1 3.3 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 KZN90652.1 - 0.0043 16.6 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KZN90652.1 - 0.0057 15.4 0.0 0.96 8.0 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 KZN90652.1 - 0.0075 16.1 0.1 0.21 11.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KZN90652.1 - 0.015 14.5 0.2 0.16 11.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KZN90652.1 - 0.015 15.4 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 KZN90652.1 - 0.016 14.9 0.0 0.3 10.7 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 KZN90652.1 - 0.039 12.9 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KZN90652.1 - 0.041 13.3 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KZN90652.1 - 0.056 12.3 0.1 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 KZN90652.1 - 0.059 13.6 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin2 PF13189.1 KZN90652.1 - 0.072 12.9 0.1 1.5 8.7 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase-like family SKI PF01202.17 KZN90652.1 - 0.076 12.8 0.0 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 KZN90652.1 - 0.085 12.5 0.1 12 5.4 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 KZN90652.1 - 0.1 11.6 0.1 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 KZN90652.1 - 0.1 12.0 0.0 4.5 6.7 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain cobW PF02492.14 KZN90652.1 - 0.11 11.9 0.9 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 KZN90652.1 - 0.22 10.7 0.1 13 4.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SET PF00856.23 KZN90655.1 - 7.1e-15 55.6 0.1 9.2e-14 52.0 0.0 2.6 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 KZN90655.1 - 8e-09 35.2 10.2 8e-09 35.2 7.1 2.0 2 0 0 2 2 2 1 MYND finger Fzo_mitofusin PF04799.8 KZN90655.1 - 0.025 13.9 0.2 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 fzo-like conserved region HTH_35 PF13693.1 KZN90655.1 - 0.082 12.7 0.0 4 7.2 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding CPSase_L_D2 PF02786.12 KZN90656.1 - 3.6e-107 356.4 0.0 1.6e-84 282.4 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KZN90656.1 - 6.5e-42 142.1 0.0 1.5e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KZN90656.1 - 3.7e-38 131.0 0.4 1.5e-20 73.7 0.1 2.7 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KZN90656.1 - 1.5e-37 128.0 0.0 6.7e-18 64.8 0.0 2.8 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KZN90656.1 - 4.2e-23 81.6 0.0 4.4e-08 32.2 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KZN90656.1 - 1.8e-17 63.1 0.0 2.5e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KZN90656.1 - 1.4e-16 60.4 0.1 1.1e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KZN90656.1 - 2e-07 30.6 0.0 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 KZN90656.1 - 0.00046 19.4 0.0 0.12 11.5 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KZN90656.1 - 0.0014 18.2 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain YfkB PF08756.5 KZN90657.1 - 0.16 11.5 0.0 2.2 7.8 0.0 2.5 2 1 1 3 3 3 0 YfkB-like domain PAT1 PF09770.4 KZN90658.1 - 1.5 7.0 17.3 2.3 6.3 12.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KZN90658.1 - 1.5 8.6 16.1 2 8.1 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.12 KZN90658.1 - 3.7 6.2 5.6 5.3 5.7 3.9 1.2 1 0 0 1 1 1 0 Presenilin Complex1_LYR_2 PF13233.1 KZN90659.1 - 0.41 11.1 9.7 2.6 8.5 2.0 3.3 2 1 1 3 3 3 0 Complex1_LYR-like Spc7 PF08317.6 KZN90659.1 - 0.56 8.8 5.0 0.14 10.8 1.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DegS PF05384.6 KZN90660.1 - 0.0086 15.3 2.4 0.039 13.1 0.7 2.1 2 0 0 2 2 2 1 Sensor protein DegS AKNA PF12443.3 KZN90660.1 - 0.011 15.6 1.2 0.067 13.2 0.4 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor SPX PF03105.14 KZN90660.1 - 0.015 15.0 6.2 0.041 13.6 4.3 1.7 1 1 0 1 1 1 0 SPX domain DUF2046 PF09755.4 KZN90660.1 - 0.045 12.6 3.4 0.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Rho_Binding PF08912.6 KZN90660.1 - 0.066 13.5 2.1 0.24 11.7 0.7 2.0 2 0 0 2 2 2 0 Rho Binding bZIP_2 PF07716.10 KZN90660.1 - 0.094 12.5 7.9 0.097 12.5 0.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.7 KZN90660.1 - 0.2 12.0 4.4 7.2 7.0 0.7 2.5 2 0 0 2 2 2 0 SlyX Striatin PF08232.7 KZN90660.1 - 0.35 11.1 8.3 1.1 9.5 0.9 2.3 2 0 0 2 2 2 0 Striatin family FlaC_arch PF05377.6 KZN90660.1 - 0.48 10.3 2.2 0.54 10.1 0.1 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Uds1 PF15456.1 KZN90660.1 - 1.6 8.7 7.7 6 6.8 0.6 2.5 2 0 0 2 2 2 0 Up-regulated During Septation CCDC14 PF15254.1 KZN90660.1 - 2 6.6 13.9 0.051 11.9 0.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 RAP1 PF07218.6 KZN90660.1 - 2.1 6.3 8.4 3 5.8 5.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ADIP PF11559.3 KZN90660.1 - 3.1 7.6 7.8 0.38 10.6 1.4 2.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 KZN90660.1 - 5.9 5.0 14.0 9.3 4.3 9.7 1.3 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 KZN90661.1 - 7.6e-09 35.0 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90661.1 - 4.6e-07 29.7 0.0 9.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN90661.1 - 6.2e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif IBN_N PF03810.14 KZN90663.1 - 7.9e-17 60.9 0.4 4.3e-12 45.7 0.0 4.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 KZN90663.1 - 1.4e-09 37.0 0.0 2.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 KZN90663.1 - 1e-05 25.4 0.6 0.0019 18.0 0.1 3.2 2 0 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KZN90663.1 - 0.0014 17.0 3.9 0.14 10.4 0.2 2.9 3 1 0 3 3 3 2 CAS/CSE protein, C-terminus DUF2435 PF10363.4 KZN90663.1 - 0.0071 16.2 0.8 0.038 13.8 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) SDA1 PF05285.7 KZN90663.1 - 3.7 6.7 10.8 6.2 6.0 7.5 1.2 1 0 0 1 1 1 0 SDA1 DSHCT PF08148.7 KZN90664.1 - 1.4e-60 203.6 0.8 3e-60 202.5 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KZN90664.1 - 1.1e-20 73.8 0.0 2.8e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90664.1 - 1.2e-06 28.2 0.0 3.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN90664.1 - 0.0015 18.3 0.0 0.019 14.8 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BRCA2 PF00634.13 KZN90664.1 - 0.037 13.3 0.4 0.08 12.2 0.3 1.6 1 0 0 1 1 1 0 BRCA2 repeat MFS_1 PF07690.11 KZN90665.1 - 2.6e-20 72.4 23.9 4.6e-20 71.6 14.8 1.9 1 1 0 2 2 2 2 Major Facilitator Superfamily MIB_HERC2 PF06701.8 KZN90666.1 - 0.0094 15.8 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Mib_herc2 DUF2415 PF10313.4 KZN90667.1 - 1.8e-17 62.7 0.1 3.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KZN90667.1 - 0.0094 15.8 2.8 1.5 8.7 0.3 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat HSP70 PF00012.15 KZN90668.1 - 1e-261 869.1 18.5 1.2e-261 868.9 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KZN90668.1 - 2.1e-15 56.1 5.4 2.5e-14 52.6 1.4 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KZN90668.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KZN90668.1 - 0.0069 16.2 7.8 0.92 9.3 2.3 4.6 2 2 0 2 2 2 1 Cell division protein FtsA THUMP PF02926.12 KZN90668.1 - 0.015 15.2 1.5 1.4 8.7 0.8 2.7 2 0 0 2 2 2 0 THUMP domain UBN_AB PF14075.1 KZN90668.1 - 1.3 8.5 7.2 3.8 7.1 5.0 1.8 1 1 0 1 1 1 0 Ubinuclein conserved middle domain IncA PF04156.9 KZN90668.1 - 2.2 7.8 10.0 4.4 6.8 6.9 1.4 1 0 0 1 1 1 0 IncA protein Hydantoinase_A PF01968.13 KZN90668.1 - 3 6.8 11.2 1.1 8.2 0.1 4.0 3 1 2 5 5 5 0 Hydantoinase/oxoprolinase Bac_globin PF01152.16 KZN90669.1 - 7 6.6 6.4 4.8 7.2 1.9 2.3 3 0 0 3 3 3 0 Bacterial-like globin DUF1682 PF07946.9 KZN90669.1 - 8.4 5.1 7.6 13 4.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Methyltransf_16 PF10294.4 KZN90670.1 - 8.8e-10 38.3 0.0 0.00018 20.9 0.0 2.6 3 0 0 3 3 3 2 Putative methyltransferase AMP-binding PF00501.23 KZN90671.1 - 4e-79 265.9 0.0 6e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN90671.1 - 0.0029 18.5 0.3 0.0075 17.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NDT80_PhoG PF05224.7 KZN90673.1 - 8.1e-37 127.0 0.0 1.5e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family eIF3g PF12353.3 KZN90674.1 - 7.4e-47 158.4 4.0 1e-46 157.9 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KZN90674.1 - 1.1e-14 53.8 0.0 1.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90674.1 - 5.1e-11 42.4 0.0 9.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90674.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_34 PF05637.7 KZN90675.1 - 1.2e-08 34.7 0.1 1.8e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 KZN90675.1 - 0.00024 20.9 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Transp_cyt_pur PF02133.10 KZN90676.1 - 1.3e-44 152.5 36.0 1.5e-44 152.2 25.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sod_Cu PF00080.15 KZN90678.1 - 1.1e-14 54.7 0.0 1.5e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KZN90678.1 - 2.9e-13 49.7 0.0 5.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 KZN90679.1 - 8.8e-64 215.1 0.0 1.3e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90679.1 - 1e-26 93.6 0.0 2.5e-26 92.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_3_C PF01915.17 KZN90679.1 - 3.4e-16 59.4 0.8 1.2e-14 54.4 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN90679.1 - 3.5e-07 30.0 0.1 7.5e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Jnk-SapK_ap_N PF09744.4 KZN90679.1 - 0.27 11.2 3.4 0.62 10.0 2.4 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3987 PF13148.1 KZN90679.1 - 4.8 5.6 7.7 7.7 4.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) VWA_3 PF13768.1 KZN90680.1 - 1.1e-30 106.4 0.1 3.2e-30 104.8 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 KZN90680.1 - 5.8e-19 67.9 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KZN90680.1 - 2.1e-14 53.9 0.0 4.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KZN90680.1 - 6.1e-13 48.8 0.1 1.1e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KZN90680.1 - 1.2e-07 31.1 0.1 2.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 KZN90680.1 - 0.00011 21.4 0.6 0.00023 20.4 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF2201 PF09967.4 KZN90680.1 - 0.008 16.1 0.1 0.081 12.9 0.1 2.3 1 1 0 1 1 1 1 VWA-like domain (DUF2201) vWA-TerF-like PF10138.4 KZN90680.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF3720 PF12517.3 KZN90681.1 - 5.4 7.7 9.0 18 6.1 4.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3720) Methyltransf_28 PF02636.12 KZN90683.1 - 3.6e-78 262.4 0.0 4.6e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 KZN90684.1 - 2.5e-14 53.5 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Flavodoxin_3 PF12641.2 KZN90684.1 - 0.054 12.9 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain Ribosomal_S21 PF01165.15 KZN90685.1 - 3.1e-11 42.5 0.9 7.1e-11 41.3 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 PGI PF00342.14 KZN90687.1 - 2.1e-217 722.3 0.9 2.4e-217 722.1 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF924 PF06041.6 KZN90687.1 - 0.04 13.6 1.4 0.78 9.4 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) PWI PF01480.12 KZN90688.1 - 4.7e-11 42.6 0.3 1.1e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 PWI domain SUKH_6 PF14568.1 KZN90688.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall RRM_1 PF00076.17 KZN90688.1 - 0.15 11.6 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MR_MLE_C PF13378.1 KZN90689.1 - 8.5e-19 67.5 0.0 2.8e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KZN90689.1 - 3.2e-15 56.3 0.0 1.3e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KZN90689.1 - 1.9e-06 27.8 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF464 PF04327.7 KZN90689.1 - 0.036 14.2 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF464) UPF0150 PF03681.10 KZN90689.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) F-box-like PF12937.2 KZN90690.1 - 1.1e-08 34.6 1.4 3.8e-08 32.9 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN90690.1 - 0.00092 18.7 1.6 0.0027 17.3 1.1 1.9 1 1 0 1 1 1 1 F-box domain DUF1682 PF07946.9 KZN90691.1 - 1.4e-113 378.9 0.4 1.6e-113 378.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RbsD_FucU PF05025.8 KZN90691.1 - 0.001 19.4 0.3 0.0016 18.7 0.2 1.3 1 0 0 1 1 1 1 RbsD / FucU transport protein family B12-binding PF02310.14 KZN90691.1 - 0.11 12.4 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain Tom37_C PF11801.3 KZN90691.1 - 0.17 11.7 3.1 0.32 10.8 2.1 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Phage_Gp23 PF10669.4 KZN90691.1 - 7 6.7 10.4 6.2 6.9 5.1 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DNAPolymera_Pol PF11590.3 KZN90692.1 - 0.5 10.0 2.3 1.2 8.8 0.3 2.1 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF2404 PF10296.4 KZN90694.1 - 0.00014 21.9 0.0 0.00053 20.0 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) IMS_C PF11799.3 KZN90694.1 - 0.026 14.4 0.0 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain TIM21 PF08294.6 KZN90695.1 - 2.8e-40 137.3 0.0 3.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KZN90695.1 - 5.1e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 KZN90696.1 - 3.2e-34 117.2 0.7 5.4e-34 116.4 0.5 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PRCC PF10253.4 KZN90696.1 - 0.054 14.1 7.6 0.039 14.6 3.8 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pterin_bind PF00809.17 KZN90697.1 - 1.2e-65 220.8 0.0 2.1e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KZN90697.1 - 2.8e-39 133.7 0.0 4.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) ArabFuran-catal PF09206.6 KZN90698.1 - 5.1e-165 548.1 22.1 7.8e-165 547.5 15.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KZN90698.1 - 2.1e-61 205.7 3.4 3.4e-61 205.1 2.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) UBN2_3 PF14244.1 KZN90699.1 - 0.057 12.9 0.2 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type adh_short PF00106.20 KZN90700.1 - 1.1e-13 51.3 0.4 1.6e-13 50.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90700.1 - 2.2e-05 24.1 0.2 3.1e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN90700.1 - 0.02 14.6 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_3 PF03447.11 KZN90700.1 - 0.023 15.0 0.3 1.1 9.7 0.0 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AAA PF00004.24 KZN90701.1 - 1.8e-17 63.7 0.0 3.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN90701.1 - 0.0002 21.4 0.0 0.00074 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN90701.1 - 0.00048 20.2 0.0 0.0022 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KZN90701.1 - 0.0032 17.2 0.0 0.009 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.7 KZN90701.1 - 0.018 14.5 0.1 0.33 10.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 KZN90701.1 - 0.025 15.3 0.1 0.099 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KZN90701.1 - 0.044 14.0 0.2 0.15 12.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KZN90701.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 KZN90701.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Tim17 PF02466.14 KZN90703.1 - 5.9e-34 116.8 6.3 7.2e-34 116.5 4.4 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KZN90703.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Ank_2 PF12796.2 KZN90704.1 - 4.4e-203 658.3 5.9 5.7e-22 77.8 0.0 10.8 2 1 11 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90704.1 - 1e-149 479.5 21.3 5.3e-09 35.4 0.0 21.1 21 0 0 21 21 21 20 Ankyrin repeat Ank_5 PF13857.1 KZN90704.1 - 3.2e-105 341.8 31.1 3.2e-10 39.9 0.0 18.4 2 1 19 21 21 21 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN90704.1 - 2.9e-99 314.9 6.4 9.3e-05 22.3 0.0 21.4 22 0 0 22 22 22 17 Ankyrin repeat Ank_4 PF13637.1 KZN90704.1 - 1.2e-97 318.7 11.9 1.8e-11 44.2 0.0 15.2 5 3 12 18 18 18 15 Ankyrin repeats (many copies) HeLo PF14479.1 KZN90704.1 - 1.9e-23 83.3 0.6 3.2e-22 79.3 0.4 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 KZN90704.1 - 5e-05 23.0 0.1 0.034 13.8 0.0 2.4 1 1 1 2 2 2 2 NACHT domain C1_3 PF07649.7 KZN90704.1 - 0.0074 16.3 5.9 0.017 15.1 4.1 1.7 1 0 0 1 1 1 1 C1-like domain NmrA PF05368.8 KZN90706.1 - 7.3e-17 61.4 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN90706.1 - 7.9e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KZN90706.1 - 1.4e-06 27.5 0.1 2.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN90706.1 - 1.7e-05 24.9 0.1 4.6e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KZN90706.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 KZN90706.1 - 0.00022 21.1 0.4 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN90706.1 - 0.002 18.5 0.5 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KZN90706.1 - 0.0031 17.1 0.0 0.012 15.3 0.0 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KZN90706.1 - 0.023 13.4 0.0 0.13 10.9 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4366 PF14283.1 KZN90708.1 - 0.042 13.2 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) NMO PF03060.10 KZN90710.1 - 4.1e-71 239.8 1.4 4.9e-71 239.5 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KZN90710.1 - 2.8e-09 36.3 0.7 6.6e-09 35.1 0.5 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KZN90710.1 - 1.1e-07 31.0 1.9 1.7e-07 30.4 1.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KZN90710.1 - 0.00024 20.1 1.9 0.00044 19.2 1.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KZN90710.1 - 0.0009 18.2 0.4 0.0014 17.6 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TPR_11 PF13414.1 KZN90711.1 - 8.5e-15 54.1 3.4 1.1e-09 37.7 0.1 3.2 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 KZN90711.1 - 2.1e-13 49.2 6.8 3.4e-06 26.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KZN90711.1 - 1e-12 46.9 5.4 0.00055 19.6 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN90711.1 - 2e-09 36.5 0.2 0.00031 20.2 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN90711.1 - 2.9e-08 33.5 0.3 0.0002 21.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN90711.1 - 3.4e-06 27.5 0.5 0.0021 18.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN90711.1 - 5.1e-06 25.8 0.7 7.6e-05 22.2 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.19 KZN90711.1 - 6.1e-06 25.8 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.1 KZN90711.1 - 2.8e-05 23.8 0.2 0.23 11.3 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN90711.1 - 8.3e-05 22.7 0.3 2.7 8.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN90711.1 - 0.017 15.3 0.1 0.63 10.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 KZN90711.1 - 0.095 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat Apc3 PF12895.2 KZN90711.1 - 0.23 11.6 1.8 0.56 10.3 0.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Di19_C PF14571.1 KZN90712.1 - 0.0061 16.8 0.2 0.0077 16.5 0.1 1.2 1 0 0 1 1 1 1 Stress-induced protein Di19, C-terminal Syntaxin-18_N PF10496.4 KZN90714.1 - 1.4e-16 60.0 3.0 2e-16 59.5 0.5 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KZN90714.1 - 5e-06 26.1 0.5 2.9e-05 23.6 0.7 2.1 2 0 0 2 2 2 1 SNARE domain DUF3819 PF12842.2 KZN90714.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3819) Aminotran_1_2 PF00155.16 KZN90715.1 - 1.6e-83 280.6 0.0 2.1e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.1 KZN90716.1 - 1.2e-15 57.0 5.4 2.1e-15 56.2 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN90716.1 - 8.4e-09 35.4 2.3 2.1e-08 34.1 1.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN90716.1 - 3e-08 33.2 4.2 5.4e-08 32.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN90716.1 - 6.5e-08 32.4 5.4 1.2e-07 31.5 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN90716.1 - 3.4e-06 26.6 1.8 3.4e-06 26.6 1.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN90716.1 - 9.3e-06 25.2 2.7 9.3e-06 25.2 1.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KZN90716.1 - 0.00011 21.9 2.4 0.00026 20.7 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KZN90716.1 - 0.00033 20.1 3.5 0.00064 19.2 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KZN90716.1 - 0.01 15.7 2.4 0.021 14.8 1.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KZN90716.1 - 0.2 11.5 9.9 0.033 14.0 4.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 KZN90716.1 - 1.5 8.9 4.0 11 6.1 0.1 3.2 3 0 0 3 3 3 0 zinc-finger FANCL_C PF11793.3 KZN90716.1 - 3.4 7.7 8.9 1.6 8.7 3.6 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain NACHT PF05729.7 KZN90717.1 - 0.02 14.5 0.1 0.083 12.5 0.1 2.1 1 0 0 1 1 1 0 NACHT domain PRTP PF01366.13 KZN90717.1 - 0.19 9.6 0.4 0.33 8.8 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus processing and transport protein PhyH PF05721.8 KZN90718.1 - 1.3e-24 87.3 0.1 2e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MS_channel PF00924.13 KZN90719.1 - 5.4e-20 71.6 0.4 1.1e-19 70.6 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KZN90719.1 - 0.00055 19.0 0.3 0.0016 17.6 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KZN90719.1 - 0.0038 17.3 0.2 0.0094 16.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KZN90719.1 - 0.0065 16.2 0.1 0.021 14.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KZN90719.1 - 0.05 12.9 0.2 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 EF hand Mgm101p PF06420.7 KZN90720.1 - 3.6e-90 299.8 0.0 4.6e-90 299.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.8 KZN90721.1 - 2.7e-07 30.3 8.5 3.8e-07 29.8 5.9 1.2 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.4 KZN90721.1 - 0.0017 18.2 1.3 0.002 18.0 0.9 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 KZN90721.1 - 0.0064 16.2 7.3 0.065 13.0 1.0 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KZN90721.1 - 0.038 13.9 4.1 0.053 13.5 2.8 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 KZN90721.1 - 0.14 12.2 4.2 0.2 11.7 2.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Toxin_25 PF08095.6 KZN90721.1 - 0.16 11.7 0.2 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 Hefutoxin family BPL_N PF09825.4 KZN90722.1 - 2.7e-139 464.0 0.0 3.4e-139 463.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KZN90722.1 - 2.5e-20 72.7 0.0 5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.6 KZN90722.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Trehalose utilisation MUG113 PF13455.1 KZN90723.1 - 2.7e-36 123.8 0.6 5.4e-36 122.9 0.4 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KZN90723.1 - 6.3e-26 90.7 0.1 1.6e-25 89.4 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain DLH PF01738.13 KZN90724.1 - 4.3e-17 62.1 0.0 2.7e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KZN90724.1 - 1.3e-07 31.5 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN90724.1 - 3.1e-05 23.9 0.0 0.00052 19.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KZN90724.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 KZN90725.1 - 3.3e-48 164.0 0.0 3.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN90725.1 - 1.9e-05 24.4 0.1 2.9e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN90725.1 - 0.00042 20.2 0.1 0.00062 19.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KZN90725.1 - 0.0019 16.8 0.0 0.0028 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 KZN90725.1 - 0.0042 15.8 0.3 0.011 14.4 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.15 KZN90725.1 - 0.015 15.4 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 KZN90725.1 - 0.044 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CN_hydrolase PF00795.17 KZN90726.1 - 3.1e-31 108.1 0.0 4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank_2 PF12796.2 KZN90727.1 - 3.9e-34 116.8 7.1 6e-11 42.5 0.1 3.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN90727.1 - 4.4e-18 65.2 0.5 0.00011 22.5 0.0 5.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN90727.1 - 2.3e-13 49.8 8.2 0.013 15.7 0.1 6.5 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KZN90727.1 - 6.1e-13 47.8 11.0 0.037 13.8 0.1 6.7 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.7 KZN90727.1 - 4.7e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KZN90727.1 - 1.4e-09 38.2 1.0 2.6e-08 34.0 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 KZN90727.1 - 6.2e-09 35.2 6.0 1.7 9.0 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat AAA_22 PF13401.1 KZN90727.1 - 0.00018 21.6 0.1 0.0017 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KZN90727.1 - 0.0021 17.4 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN90727.1 - 0.011 15.9 0.1 0.089 12.9 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN90727.1 - 0.04 14.7 0.8 0.9 10.3 0.1 3.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KZN90727.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF3447 PF11929.3 KZN90727.1 - 0.12 12.2 0.0 11 5.9 0.0 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF3447) Aldedh PF00171.17 KZN90728.1 - 1.8e-163 544.1 0.8 5.2e-161 536.0 0.6 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DHDPS PF00701.17 KZN90729.1 - 6.8e-64 215.2 0.0 7.7e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 KZN90730.1 - 1.4e-46 158.8 3.1 1.8e-46 158.4 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90730.1 - 1.4e-09 37.7 7.9 2.8e-09 36.7 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 KZN90731.1 - 2.4e-116 388.5 0.0 5e-116 387.4 0.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KZN90731.1 - 5.5e-07 28.7 0.1 9.5e-07 28.0 0.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KZN90731.1 - 0.00013 20.9 0.0 0.00025 20.0 0.0 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KZN90731.1 - 0.00052 19.3 0.0 0.026 13.8 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 KZN90731.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KZN90731.1 - 0.0057 15.6 0.1 0.0087 15.0 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.9 KZN90731.1 - 0.0071 15.4 0.0 0.19 10.8 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Adeno_PVIII PF01310.13 KZN90732.1 - 0.0022 17.8 0.1 0.0025 17.6 0.1 1.0 1 0 0 1 1 1 1 Adenovirus hexon associated protein, protein VIII bZIP_1 PF00170.16 KZN90733.1 - 0.013 15.4 2.0 0.013 15.4 1.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor GPP34 PF05719.6 KZN90733.1 - 0.016 15.2 1.0 0.036 14.1 0.7 1.6 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) p450 PF00067.17 KZN90734.1 - 5.4e-59 199.9 0.0 7.3e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 KZN90735.1 - 3e-55 187.4 1.8 4.2e-55 186.9 1.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KZN90735.1 - 5.9e-14 51.4 9.9 5.9e-14 51.4 6.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF605 PF04652.11 KZN90735.1 - 6.2 6.1 14.2 8.9 5.6 9.9 1.1 1 0 0 1 1 1 0 Vta1 like NRDE PF05742.7 KZN90736.1 - 8.9e-46 156.3 0.0 4.5e-45 154.0 0.0 1.8 1 1 0 1 1 1 1 NRDE protein TB2_DP1_HVA22 PF03134.14 KZN90737.1 - 3.4e-29 100.4 6.1 4.9e-29 99.9 4.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MIF4G PF02854.14 KZN90739.1 - 2.9e-51 173.8 0.0 4.1e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KZN90739.1 - 8.9e-19 67.1 0.2 8.9e-19 67.1 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 AAA_23 PF13476.1 KZN90739.1 - 1.4 9.1 9.5 2.9 8.1 6.6 1.5 1 0 0 1 1 1 0 AAA domain Usp PF00582.21 KZN90740.1 - 5.8e-21 75.1 1.9 3.3e-20 72.7 0.1 2.6 3 0 0 3 3 3 1 Universal stress protein family TFIIA PF03153.8 KZN90741.1 - 0.87 9.4 8.5 1.4 8.7 5.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tom22 PF04281.8 KZN90741.1 - 9.1 5.8 12.6 6.6 6.2 2.8 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pro-kuma_activ PF09286.6 KZN90743.1 - 6e-50 168.9 0.1 4.7e-49 166.0 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KZN90743.1 - 0.0026 16.9 0.1 0.0043 16.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family AICARFT_IMPCHas PF01808.13 KZN90744.1 - 4.6e-109 364.3 0.0 6.3e-109 363.8 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KZN90744.1 - 4.3e-25 87.4 0.0 9.4e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain INSIG PF07281.7 KZN90745.1 - 1.6e-83 278.8 1.1 2e-83 278.5 0.8 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DEAD PF00270.24 KZN90747.1 - 6.5e-46 155.9 0.0 1.6e-44 151.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90747.1 - 3.1e-28 97.4 0.1 6.1e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN90747.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 KZN90747.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KZN90747.1 - 0.087 11.2 0.0 0.17 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Pro_isomerase PF00160.16 KZN90748.1 - 4.3e-45 153.6 0.5 5.2e-45 153.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 KZN90749.1 - 1.1e-18 67.6 0.7 1.2e-18 67.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 WD40 PF00400.27 KZN90750.1 - 2.7e-33 112.6 14.4 6.1e-07 29.0 0.2 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 KZN90750.1 - 6.4e-22 77.3 0.1 1.2e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KZN90750.1 - 0.0012 17.1 4.1 1 7.4 0.8 3.5 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Zw10 PF06248.8 KZN90751.1 - 8.8e-15 53.8 0.7 2.5e-12 45.7 0.3 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KZN90751.1 - 7e-09 35.2 0.1 7e-09 35.2 0.1 2.2 2 1 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 KZN90751.1 - 0.037 14.4 0.0 0.037 14.4 0.0 3.8 4 1 1 5 5 5 0 Syntaxin 6, N-terminal BUD22 PF09073.5 KZN90751.1 - 0.062 12.3 11.3 0.11 11.5 7.8 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KZN90751.1 - 0.082 10.8 25.2 0.0058 14.6 13.5 1.9 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 KZN90751.1 - 0.59 8.5 15.1 0.52 8.7 9.5 1.5 2 0 0 2 2 2 0 Daxx Family Peptidase_M16_C PF05193.16 KZN90752.1 - 1.8e-15 57.1 0.0 1e-08 35.0 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KZN90752.1 - 1.6e-05 24.6 0.0 6e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ribosomal_L34 PF00468.12 KZN90753.1 - 7.6e-13 47.9 12.2 1.7e-12 46.8 8.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 Clathrin_H_link PF13838.1 KZN90753.1 - 0.12 12.2 0.4 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Clathrin-H-link Mucin PF01456.12 KZN90753.1 - 0.53 10.0 7.5 0.72 9.6 5.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RNA_polI_A14 PF08203.6 KZN90754.1 - 0.00025 21.1 0.0 0.00074 19.7 0.0 1.7 1 0 0 1 1 1 1 Yeast RNA polymerase I subunit RPA14 Peptidase_M48 PF01435.13 KZN90755.1 - 1.5e-49 168.5 0.0 2.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.1 KZN90755.1 - 0.081 12.2 0.8 0.19 11.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 KZN90755.1 - 0.11 11.6 0.3 0.26 10.4 0.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain eIF2_C PF09173.6 KZN90756.1 - 1.3e-36 124.4 0.2 2.4e-36 123.6 0.2 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 KZN90756.1 - 1.4e-18 66.9 0.2 2e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KZN90756.1 - 2e-12 47.0 0.3 4.5e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 WD40 PF00400.27 KZN90757.1 - 5e-12 45.2 0.1 0.011 15.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat HSA PF07529.8 KZN90758.1 - 4.3e-25 87.2 0.7 4.3e-25 87.2 0.5 3.5 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 KZN90758.1 - 7.3e-16 58.0 2.0 8.8e-16 57.7 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN90758.1 - 0.0072 16.3 1.4 0.021 14.8 0.1 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF4419 PF14388.1 KZN90759.1 - 1e-98 330.2 0.0 1.2e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) RTA1 PF04479.8 KZN90760.1 - 3.8e-39 134.4 0.7 5.9e-39 133.8 0.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DsbD_2 PF13386.1 KZN90760.1 - 5 6.8 10.0 1.8 8.2 0.8 3.4 2 1 3 5 5 5 0 Cytochrome C biogenesis protein transmembrane region G-patch_2 PF12656.2 KZN90761.1 - 7e-28 96.2 0.0 7e-28 96.2 0.0 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 KZN90761.1 - 0.00031 20.4 0.2 0.00081 19.1 0.1 1.8 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.27 KZN90762.1 - 1.1e-77 253.3 29.9 4.7e-10 38.9 0.0 13.4 13 2 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 KZN90762.1 - 2e-45 153.8 0.0 3.1e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KZN90762.1 - 7.7e-08 30.9 9.4 0.13 10.3 0.1 6.6 3 3 3 7 7 7 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KZN90762.1 - 0.00012 20.9 5.3 0.86 8.2 0.1 5.2 2 2 1 5 5 5 3 Nup133 N terminal like DUF3312 PF11768.3 KZN90762.1 - 0.043 12.0 0.0 0.13 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Proteasome PF00227.21 KZN90764.1 - 3.7e-37 127.4 0.0 5.8e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 KZN90764.1 - 3.3e-20 72.3 0.0 1.3e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KZN90764.1 - 4.8e-12 45.8 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.27 KZN90765.1 - 1.8e-30 103.6 16.5 1.1e-08 34.6 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4 PF00097.20 KZN90766.1 - 4.4e-09 35.8 4.4 4.4e-09 35.8 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN90766.1 - 6.6e-09 35.4 6.8 6.6e-09 35.4 4.7 2.5 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 KZN90766.1 - 5.1e-08 32.6 7.0 5.1e-08 32.6 4.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KZN90766.1 - 1.3e-07 31.5 7.3 1.3e-07 31.5 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN90766.1 - 1.5e-07 30.9 3.7 1.5e-07 30.9 2.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN90766.1 - 7e-07 28.8 5.6 7e-07 28.8 3.9 2.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KZN90766.1 - 7.1e-05 22.4 1.8 7.1e-05 22.4 1.2 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KZN90766.1 - 0.0046 17.0 8.9 0.0079 16.2 2.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN90766.1 - 0.0075 16.0 1.0 0.0075 16.0 0.7 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KZN90766.1 - 0.011 15.5 8.3 1.5 8.7 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_6 PF14835.1 KZN90766.1 - 0.013 15.2 3.3 0.013 15.2 2.3 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SDA1 PF05285.7 KZN90766.1 - 0.041 13.1 21.4 0.22 10.7 9.5 2.3 2 0 0 2 2 2 0 SDA1 IBR PF01485.16 KZN90766.1 - 0.37 10.6 8.8 6.1 6.7 3.5 3.0 1 1 1 2 2 2 0 IBR domain DUF1903 PF08991.5 KZN90767.1 - 1.9e-05 24.6 2.5 2.7e-05 24.2 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KZN90767.1 - 2.3e-05 24.1 6.1 4e-05 23.3 4.3 1.4 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 KZN90767.1 - 0.051 13.4 6.1 0.11 12.3 3.6 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) JTB PF05439.7 KZN90767.1 - 0.11 12.3 0.8 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Cmc1 PF08583.5 KZN90767.1 - 0.15 11.8 6.6 0.2 11.4 1.0 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NatB_MDM20 PF09797.4 KZN90768.1 - 1.1e-70 238.2 0.0 2.1e-70 237.3 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ribosomal_L36e PF01158.13 KZN90768.1 - 3.2e-34 116.8 5.6 3.2e-34 116.8 3.9 2.3 2 0 0 2 2 2 1 Ribosomal protein L36e TPR_19 PF14559.1 KZN90768.1 - 0.0079 16.5 3.4 0.8 10.0 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN90768.1 - 0.021 15.4 1.7 7.2 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN90768.1 - 5.1 8.0 7.1 60 4.6 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TUG-UBL1 PF11470.3 KZN90769.1 - 8.2e-26 89.7 0.1 1.9e-25 88.5 0.1 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 KZN90769.1 - 0.004 17.1 0.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 UBX domain Proteasome PF00227.21 KZN90770.1 - 1.6e-41 141.6 0.0 1.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EHN PF06441.7 KZN90771.1 - 1.2e-32 112.1 1.4 1.6e-31 108.5 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 KZN90771.1 - 5.4e-05 22.8 0.0 0.00032 20.3 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN90771.1 - 9.3e-05 22.4 0.5 0.00066 19.6 0.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family RuvC PF02075.12 KZN90771.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC T_cell_tran_alt PF15128.1 KZN90772.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered DUF2790 PF10976.3 KZN90772.1 - 0.16 11.7 0.0 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) HATPase_c PF02518.21 KZN90773.1 - 1.8e-16 59.8 0.0 3.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN90773.1 - 2.9e-15 56.2 0.2 0.00019 21.4 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 KZN90773.1 - 4.5e-05 23.3 0.2 0.00031 20.6 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain EMP24_GP25L PF01105.19 KZN90774.1 - 3.1e-52 176.9 0.3 3.6e-52 176.7 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 KZN90775.1 - 0.045 13.8 0.1 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1388 PF07142.7 KZN90776.1 - 4e-05 23.2 4.1 4e-05 23.2 2.8 2.1 2 0 0 2 2 2 1 Repeat of unknown function (DUF1388) Transaldolase PF00923.14 KZN90777.1 - 1.1e-35 123.2 2.6 1.2e-35 123.0 1.8 1.1 1 0 0 1 1 1 1 Transaldolase MFS_1 PF07690.11 KZN90778.1 - 3.4e-25 88.5 37.3 5e-25 87.9 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90778.1 - 2.7e-07 29.5 18.0 2.7e-07 29.5 12.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Gly_transf_sug PF04488.10 KZN90779.1 - 5.2e-08 33.2 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KZN90779.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Glyco_hydro_72 PF03198.9 KZN90780.1 - 2.2e-90 302.8 5.4 2.9e-90 302.4 3.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KZN90780.1 - 6.4e-27 93.8 7.1 1.5e-26 92.6 4.9 1.7 1 0 0 1 1 1 1 X8 domain DUF2164 PF09932.4 KZN90780.1 - 0.074 12.8 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) zf-met2 PF12907.2 KZN90781.1 - 1.5e-18 66.4 0.8 2.2e-18 65.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KZN90781.1 - 3.4e-07 30.8 12.1 5.8e-07 30.1 8.4 1.4 1 0 0 1 1 1 1 4F5 protein family adh_short_C2 PF13561.1 KZN90782.1 - 1e-25 90.9 0.0 1.2e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN90782.1 - 1.2e-20 74.0 0.0 1.3e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90782.1 - 3.7e-06 26.7 0.0 4.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN90782.1 - 0.0018 17.7 0.0 0.0059 16.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Meth_synt_2 PF01717.13 KZN90783.1 - 1.5e-132 441.4 0.0 2.4e-128 427.6 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KZN90783.1 - 8.3e-123 409.5 0.0 3.6e-111 371.3 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Abhydrolase_6 PF12697.2 KZN90784.1 - 3e-27 95.9 0.4 4e-27 95.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN90784.1 - 3.1e-22 79.2 0.0 1.2e-21 77.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN90784.1 - 9.1e-13 48.1 0.0 2.5e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN90784.1 - 0.0005 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KZN90784.1 - 0.0036 17.1 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Peptidase_S28 PF05577.7 KZN90784.1 - 0.026 13.1 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.15 KZN90784.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S10 PF00450.17 KZN90785.1 - 2.4e-76 257.5 0.0 4.2e-76 256.7 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KZN90785.1 - 0.0001 22.3 0.1 0.0035 17.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN90785.1 - 0.0043 16.8 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Tcp11 PF05794.8 KZN90786.1 - 2.9e-121 405.2 0.0 7.1e-121 403.9 0.0 1.5 1 1 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.5 KZN90786.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Imelysin Dpoe2NT PF12213.3 KZN90786.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal CTP_transf_2 PF01467.21 KZN90788.1 - 3.1e-05 24.0 0.0 9e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase DUF4536 PF15055.1 KZN90789.1 - 0.002 18.1 0.3 0.0043 17.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF2416 PF10315.4 KZN90789.1 - 0.0022 18.2 0.1 0.0026 17.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF1977 PF09320.6 KZN90790.1 - 2.7e-28 98.3 0.0 5e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KZN90790.1 - 7.4e-23 80.0 0.7 1.6e-22 78.9 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 KZN90790.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Phage_tail_S PF05069.8 KZN90790.1 - 0.019 14.7 0.2 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 Phage virion morphogenesis family Ufd2P_core PF10408.4 KZN90791.1 - 1.3e-201 671.2 11.0 1.6e-201 670.8 7.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KZN90791.1 - 1.4e-25 89.0 0.5 3.9e-25 87.6 0.4 1.9 1 0 0 1 1 1 1 U-box domain OmpH PF03938.9 KZN90791.1 - 3.2 7.6 10.3 4.3 7.2 0.6 3.8 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Steroid_dh PF02544.11 KZN90792.1 - 1.1e-15 57.7 0.4 1.7e-06 27.9 0.1 3.4 3 1 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KZN90792.1 - 0.0059 15.9 0.2 0.015 14.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF21 PF01595.15 KZN90792.1 - 1.6 8.0 10.4 9.8 5.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF21 NfeD PF01957.13 KZN90793.1 - 4.1 7.5 10.2 0.24 11.5 0.5 3.1 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Tyrosinase PF00264.15 KZN90794.1 - 1.5e-48 165.9 0.3 2e-48 165.4 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.23 KZN90795.1 - 6.1e-06 25.7 1.9 0.00012 21.5 1.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN90795.1 - 0.00018 21.3 0.7 0.00041 20.2 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cofilin_ADF PF00241.15 KZN90796.1 - 2.1e-25 89.0 0.1 2.3e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SOG2 PF10428.4 KZN90797.1 - 3e-86 289.8 6.9 5.2e-49 167.1 0.0 3.8 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 KZN90797.1 - 1.9e-16 59.2 1.9 6.4e-10 38.4 1.5 3.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN90797.1 - 1.6e-11 43.8 4.0 1.9e-07 30.7 0.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KZN90797.1 - 9.8e-11 40.1 3.0 0.047 13.7 0.2 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KZN90797.1 - 1.8e-06 27.2 2.9 2.7 8.5 0.0 5.0 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KZN90797.1 - 0.031 14.3 3.6 15 6.0 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.1 KZN90798.1 - 1e-89 299.9 2.3 1.2e-89 299.7 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Motilin_assoc PF04643.7 KZN90798.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide PPR_2 PF13041.1 KZN90799.1 - 1.6e-10 40.7 0.8 0.00015 21.6 0.0 4.1 3 2 2 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KZN90799.1 - 2.8e-08 33.4 1.4 0.011 15.9 0.0 5.1 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 KZN90799.1 - 1.4e-05 24.7 0.4 0.0084 16.0 0.0 4.1 4 0 0 4 4 4 1 PPR repeat Helicase_C PF00271.26 KZN90800.1 - 4.2e-18 64.9 0.0 9.9e-15 54.1 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KZN90800.1 - 3.2e-16 59.2 0.0 5.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase KH_1 PF00013.24 KZN90801.1 - 3.1e-09 36.3 0.0 8.3e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KZN90801.1 - 2.4e-06 27.0 2.3 0.001 18.6 0.1 3.3 4 0 0 4 4 4 2 KH domain ALS_ss_C PF10369.4 KZN90802.1 - 1.3e-19 69.6 0.0 2.4e-18 65.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KZN90802.1 - 7.3e-11 41.3 0.1 1.4e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KZN90802.1 - 2.9e-09 36.5 0.0 5.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KZN90802.1 - 0.0092 15.6 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 ACT domain LEA_2 PF03168.8 KZN90803.1 - 5.3e-06 26.7 0.5 0.0088 16.4 0.1 3.9 4 0 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.3 KZN90803.1 - 7.3e-05 22.7 1.4 0.00055 19.9 0.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) SEEEED PF14797.1 KZN90803.1 - 1 9.4 3.9 1.7 8.7 2.7 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex OTCace_N PF02729.16 KZN90804.1 - 2.3e-43 147.2 0.1 4.4e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KZN90804.1 - 1.7e-41 141.6 0.0 2.8e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain FAD_binding_3 PF01494.14 KZN90805.1 - 5.7e-14 51.9 0.2 2.5e-13 49.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN90805.1 - 2.8e-06 27.5 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN90805.1 - 0.0031 16.4 1.4 1.3 7.8 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN90805.1 - 0.0081 16.1 0.1 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KZN90805.1 - 0.011 14.6 0.0 0.16 10.7 0.0 2.2 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 KZN90805.1 - 0.016 13.8 0.1 0.13 10.8 0.0 2.0 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KZN90805.1 - 0.021 14.6 0.6 0.093 12.4 0.2 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KZN90805.1 - 0.085 12.7 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3984 PF13136.1 KZN90806.1 - 1.3e-111 372.9 17.6 1.7e-111 372.5 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Cut8_C PF08559.5 KZN90807.1 - 4.5e-51 172.4 0.0 6e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KZN90807.1 - 1e-14 53.9 1.3 2.1e-14 53.0 0.9 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 KZN90807.1 - 1.5e-12 47.3 6.9 2.7e-12 46.4 4.8 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain rRNA_proc-arch PF13234.1 KZN90808.1 - 5.2e-101 337.3 0.1 1e-100 336.3 0.1 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KZN90808.1 - 1.2e-65 220.1 1.7 2.5e-65 219.0 1.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KZN90808.1 - 1.8e-21 76.3 0.3 4.9e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN90808.1 - 2.3e-07 30.5 0.0 5.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KZN90808.1 - 0.0065 15.4 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF3121 PF11319.3 KZN90808.1 - 0.022 14.2 0.0 0.065 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) ResIII PF04851.10 KZN90808.1 - 0.041 13.7 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Prp19 PF08606.6 KZN90808.1 - 0.084 12.6 0.1 1.2 8.9 0.1 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like COX7C PF02935.11 KZN90809.1 - 8e-15 54.3 1.1 1.2e-14 53.8 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 KZN90810.1 - 0 1121.9 0.0 0 1121.6 0.0 1.1 1 0 0 1 1 1 1 IKI3 family GHMP_kinases_N PF00288.21 KZN90811.1 - 3.9e-11 42.8 0.4 9.1e-11 41.6 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 KZN90812.1 - 1.8e-76 257.1 0.1 1.2e-71 241.3 0.0 1.9 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.1 KZN90813.1 - 3.8e-25 87.8 7.4 5.5e-25 87.3 1.9 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KZN90813.1 - 1.7e-16 59.6 2.7 1.7e-16 59.6 1.8 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KZN90813.1 - 6e-05 23.1 1.9 6e-05 23.1 1.3 2.8 2 2 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 KZN90813.1 - 0.0042 16.6 2.2 0.01 15.4 0.4 2.4 2 0 0 2 2 2 1 Synaptobrevin OmpH PF03938.9 KZN90813.1 - 0.044 13.7 6.9 0.067 13.1 4.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) T2SF PF00482.18 KZN90813.1 - 0.1 12.5 0.8 0.21 11.4 0.2 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF883 PF05957.8 KZN90813.1 - 0.11 12.9 0.1 0.11 12.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 KZN90813.1 - 0.16 11.7 2.4 3.1 7.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 KZN90813.1 - 0.26 11.6 0.3 0.26 11.6 0.2 3.7 2 1 2 4 4 4 0 SlyX Ndc1_Nup PF09531.5 KZN90814.1 - 2.1e-156 521.8 0.8 2.4e-156 521.6 0.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Vfa1 PF08432.5 KZN90815.1 - 2.7e-64 216.5 16.8 3.1e-64 216.3 11.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KZN90815.1 - 0.00097 17.2 11.7 0.00097 17.2 8.1 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2201_N PF13203.1 KZN90815.1 - 0.066 12.3 6.3 0.075 12.1 4.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_21 PF13304.1 KZN90815.1 - 0.077 12.9 2.6 0.092 12.6 1.8 1.0 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 KZN90815.1 - 0.079 10.6 11.7 0.086 10.5 8.1 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 KZN90815.1 - 0.15 12.0 7.7 0.16 11.9 5.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Raftlin PF15250.1 KZN90815.1 - 0.47 8.9 7.5 0.57 8.6 5.2 1.1 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.5 KZN90815.1 - 0.63 9.1 25.9 0.85 8.7 18.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adaptin_binding PF10199.4 KZN90815.1 - 1.5 9.1 16.7 2.1 8.6 11.6 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 NARP1 PF12569.3 KZN90815.1 - 1.7 7.2 16.6 2.3 6.8 11.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Astro_capsid PF03115.9 KZN90815.1 - 1.8 6.7 5.9 1.9 6.6 4.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FLO_LFY PF01698.11 KZN90815.1 - 1.9 7.2 10.9 2.5 6.8 7.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIF_alpha PF05793.7 KZN90815.1 - 2.4 6.4 30.7 3.2 6.0 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0560 PF10577.4 KZN90815.1 - 3.3 5.8 11.6 4 5.5 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FKBP_N PF01346.13 KZN90815.1 - 3.5 7.6 12.2 2.3 8.2 7.2 1.6 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Iron_permease PF04120.7 KZN90815.1 - 4.7 6.7 5.1 10 5.7 3.5 1.5 1 0 0 1 1 1 0 Low affinity iron permease Atrophin-1 PF03154.10 KZN90815.1 - 6.4 4.7 12.6 7.2 4.6 8.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family Paramyxo_ncap PF00973.14 KZN90815.1 - 8.2 4.9 8.1 8.9 4.8 5.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1510 PF07423.6 KZN90815.1 - 8.5 5.6 25.0 12 5.2 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KZN90815.1 - 9.6 5.9 9.6 13 5.5 6.6 1.2 1 0 0 1 1 1 0 DDHD domain DSPc PF00782.15 KZN90816.1 - 3.5e-25 88.1 0.0 4.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KZN90816.1 - 0.0014 17.6 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KZN90816.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KZN90816.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-DNA_Pol PF08996.5 KZN90816.1 - 0.2 10.9 0.3 13 5.0 0.0 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.1 KZN90817.1 - 1.8e-05 24.7 23.4 0.031 14.6 2.2 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN90817.1 - 0.005 17.1 23.7 0.031 14.6 1.4 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-CHCC PF10276.4 KZN90817.1 - 0.079 12.8 3.4 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-FCS PF06467.9 KZN90817.1 - 0.14 11.8 7.4 1.6 8.4 0.1 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif 4HBT PF03061.17 KZN90818.1 - 0.0017 18.3 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily FMN_dh PF01070.13 KZN90819.1 - 4.8e-106 354.6 0.0 5.6e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KZN90819.1 - 5.4e-05 22.2 0.1 9.3e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KZN90819.1 - 0.00087 18.6 0.5 0.025 13.8 0.1 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 KZN90819.1 - 0.0019 17.1 0.1 0.0027 16.6 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KZN90819.1 - 0.048 12.7 0.3 1.1 8.3 0.1 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 KZN90819.1 - 0.19 10.8 2.6 0.37 9.9 1.8 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Asp PF00026.18 KZN90820.1 - 6.5e-71 239.1 1.1 8.7e-71 238.7 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KZN90820.1 - 2.6e-09 37.2 0.0 1.7e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KZN90820.1 - 0.00014 22.2 0.0 0.14 12.6 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KZN90820.1 - 0.00071 19.1 0.1 0.003 17.1 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal CHASE PF03924.8 KZN90820.1 - 0.0029 16.8 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 CHASE domain FMN_dh PF01070.13 KZN90822.1 - 4.5e-112 374.4 0.0 5.5e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KZN90822.1 - 2.4e-18 65.6 0.0 6.5e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KZN90822.1 - 8.8e-05 21.5 0.0 0.00018 20.5 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.10 KZN90822.1 - 0.0011 18.2 0.1 0.53 9.3 0.0 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KZN90822.1 - 0.0039 16.1 0.4 0.033 13.0 0.2 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KZN90822.1 - 0.026 13.6 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG TatD_DNase PF01026.16 KZN90823.1 - 8.9e-50 169.2 0.0 1e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.8 KZN90824.1 - 3.5e-13 49.2 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2620 PF10941.3 KZN90825.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Peptidase_C13 PF01650.13 KZN90826.1 - 2.1e-06 27.2 0.0 3.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Aa_trans PF01490.13 KZN90827.1 - 1e-72 244.8 25.5 1.2e-72 244.6 17.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF908 PF06012.7 KZN90828.1 - 2.1 7.5 4.4 1.5 8.0 1.2 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) Rad52_Rad22 PF04098.10 KZN90829.1 - 8.4e-62 207.4 0.1 1.2e-61 206.8 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBA PF00627.26 KZN90830.1 - 5.1e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 KZN90830.1 - 0.043 14.1 0.2 0.074 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Hydantoinase_B PF02538.9 KZN90830.1 - 0.087 11.0 3.9 0.12 10.5 2.7 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Crystallin PF00525.13 KZN90830.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal Pol_alpha_B_N PF08418.5 KZN90830.1 - 0.44 10.0 14.4 0.49 9.8 9.5 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1421 PF07223.6 KZN90830.1 - 0.52 10.0 9.4 1.8 8.2 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) SOBP PF15279.1 KZN90830.1 - 3.9 7.7 8.9 4.8 7.4 6.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein GAGA_bind PF06217.7 KZN90830.1 - 5.4 6.8 13.8 7.3 6.4 9.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Lipoprotein_X PF03305.8 KZN90830.1 - 8.3 5.7 12.7 17 4.6 8.8 1.5 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Motile_Sperm PF00635.21 KZN90831.1 - 2.3e-26 91.5 0.2 4.4e-26 90.6 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Phage_GP20 PF06810.6 KZN90831.1 - 0.015 14.7 1.2 0.024 14.0 0.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 FA_desaturase PF00487.19 KZN90832.1 - 1.5e-26 93.4 14.0 2.1e-26 92.8 9.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KZN90832.1 - 8.2e-20 69.7 0.2 1.8e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.19 KZN90833.1 - 2.1e-45 154.8 0.1 2.8e-45 154.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2924 PF11149.3 KZN90833.1 - 0.15 12.1 0.2 0.15 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) LZ_Tnp_IS66 PF13007.2 KZN90833.1 - 1.4 9.6 7.6 3.5 8.3 5.3 1.7 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Ank_2 PF12796.2 KZN90834.1 - 9.3e-26 90.0 0.1 7e-07 29.5 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN90834.1 - 3.8e-15 55.9 6.8 0.033 14.7 0.0 8.0 4 3 6 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.25 KZN90834.1 - 2.2e-14 52.4 5.4 0.049 13.4 0.1 7.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 KZN90834.1 - 1.5e-10 40.2 4.5 5.6 7.5 0.0 8.6 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.1 KZN90834.1 - 1.2e-06 28.5 3.3 16 5.9 0.0 7.1 6 2 2 8 8 8 2 Ankyrin repeats (many copies) Git3 PF11710.3 KZN90835.1 - 1.3e-24 86.9 9.9 1.3e-24 86.9 6.9 2.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KZN90835.1 - 2e-10 40.2 1.1 1e-09 38.0 0.0 2.6 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KZN90835.1 - 0.0051 15.9 7.5 0.0069 15.5 4.6 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ank_2 PF12796.2 KZN90836.1 - 5.6e-45 151.6 20.1 1.9e-13 50.5 1.9 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN90836.1 - 3.3e-23 80.2 7.2 2.6e-05 23.8 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 KZN90836.1 - 4.4e-19 66.6 7.8 0.0012 18.8 0.0 7.7 6 1 1 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KZN90836.1 - 5e-19 68.2 3.8 1e-07 32.2 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN90836.1 - 1.1e-13 50.9 10.8 0.0023 18.1 0.5 6.2 3 3 3 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.2 KZN90836.1 - 4.1e-05 23.2 0.0 9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN90836.1 - 0.00015 21.3 0.7 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain DnaJ PF00226.26 KZN90837.1 - 3.4e-12 45.9 0.2 5.5e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 KZN90838.1 - 6.2e-66 222.4 0.2 8.8e-66 221.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 KZN90839.1 - 2.5e-68 230.3 0.0 3.4e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KZN90839.1 - 5.4e-38 129.5 0.0 9.6e-38 128.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KZN90839.1 - 2.5e-29 101.9 0.0 7.7e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KZN90839.1 - 8.9e-08 31.6 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KZN90839.1 - 0.0007 18.3 0.0 0.036 12.7 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KZN90839.1 - 0.0031 16.4 0.0 0.0057 15.5 0.0 1.5 1 1 0 1 1 1 1 NAD synthase DUF2939 PF11159.3 KZN90839.1 - 0.14 12.3 0.0 0.75 10.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) UQ_con PF00179.21 KZN90840.1 - 7.4e-44 148.5 0.0 8.7e-44 148.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN90840.1 - 0.024 14.3 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF1325 PF07039.6 KZN90841.1 - 0.21 11.2 0.5 0.86 9.2 0.0 2.2 2 1 1 3 3 3 0 SGF29 tudor-like domain G-patch PF01585.18 KZN90842.1 - 5.2e-09 35.7 2.3 9.6e-09 34.8 1.2 1.8 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 KZN90842.1 - 8.4e-05 22.3 0.0 0.0003 20.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KZN90842.1 - 0.0082 15.9 0.6 0.032 14.0 0.4 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 KZN90842.1 - 0.022 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90842.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 KZN90843.1 - 4.7e-69 228.1 0.1 9.7e-23 79.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 KZN90844.1 - 1.8e-45 152.9 0.1 2.1e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.19 KZN90844.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Ferritin-like domain DUF4211 PF13926.1 KZN90844.1 - 0.075 12.4 0.1 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) HhH-GPD PF00730.20 KZN90845.1 - 4.5e-15 55.8 0.0 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 KZN90845.1 - 0.036 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) RuvB_C PF05491.8 KZN90845.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB C-terminus Ecm33 PF12454.3 KZN90846.1 - 5.6e-14 51.7 0.6 5.6e-14 51.7 0.4 2.4 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 KZN90846.1 - 4.5e-07 29.8 0.6 0.47 10.4 0.0 4.7 1 1 5 6 6 6 4 Receptor L domain LRR_5 PF13306.1 KZN90846.1 - 1.6e-06 27.8 0.1 0.064 12.9 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Herpes_env PF01673.13 KZN90847.1 - 0.014 13.9 0.2 0.018 13.6 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF972 PF06156.8 KZN90847.1 - 1.1 9.6 5.8 0.33 11.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 KZN90847.1 - 1.3 8.5 4.9 2.9 7.4 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Anp1 PF03452.9 KZN90848.1 - 1.1e-107 359.2 0.0 1.3e-107 358.9 0.0 1.1 1 0 0 1 1 1 1 Anp1 YCII PF03795.9 KZN90849.1 - 1.9e-09 37.5 0.0 2.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain NifU_N PF01592.11 KZN90850.1 - 5.2e-52 175.1 0.1 6.6e-52 174.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain ABC1 PF03109.11 KZN90851.1 - 7.3e-33 113.0 0.0 1.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KZN90851.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KZN90852.1 - 1.1e-70 237.8 0.0 2.6e-70 236.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90852.1 - 1.1e-50 172.1 0.0 2.3e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN90852.1 - 0.0018 17.3 0.0 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SPT2 PF08243.6 KZN90852.1 - 0.13 12.5 5.9 0.12 12.6 2.6 2.1 2 0 0 2 2 2 0 SPT2 chromatin protein FBP PF07299.6 KZN90852.1 - 0.26 10.6 0.8 14 4.9 0.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Mur_ligase_M PF08245.7 KZN90853.1 - 3.6e-07 30.4 0.2 9.9e-07 28.9 0.2 1.7 1 1 0 1 1 1 1 Mur ligase middle domain AAA_17 PF13207.1 KZN90855.1 - 0.00043 21.0 0.2 0.0017 19.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KZN90855.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KZN90855.1 - 0.0073 16.6 0.4 0.05 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN90855.1 - 0.012 15.4 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KZN90855.1 - 0.019 14.0 0.1 0.059 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KZN90855.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KZN90855.1 - 0.028 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KZN90855.1 - 0.054 12.3 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KZN90855.1 - 0.062 13.0 0.3 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 Part of AAA domain Ribonuc_red_lgC PF02867.10 KZN90857.1 - 1.4e-213 710.3 0.0 2.4e-213 709.5 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KZN90857.1 - 1e-22 79.7 1.0 2.8e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KZN90857.1 - 3.7e-15 56.1 0.0 9.7e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Glyco_transf_25 PF01755.12 KZN90858.1 - 0.0044 16.6 0.0 0.0099 15.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DAP_epimerase PF01678.14 KZN90858.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase DPBB_1 PF03330.13 KZN90859.1 - 0.0004 20.3 0.1 0.0012 18.7 0.1 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KZN90859.1 - 0.0024 17.5 0.2 0.0061 16.2 0.1 1.6 1 0 0 1 1 1 1 Barwin family BPL_C PF02237.12 KZN90859.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain NiFe_hyd_SSU_C PF14720.1 KZN90859.1 - 0.24 11.4 3.3 3.2 7.8 0.3 2.3 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal FAA_hydrolase PF01557.13 KZN90860.1 - 2.1e-56 190.8 0.0 2.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.14 KZN90861.1 - 7.7e-17 61.3 3.4 1.1e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN90861.1 - 9.9e-06 24.6 7.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN90861.1 - 0.0022 16.9 0.5 0.0078 15.1 0.1 2.0 2 1 0 2 2 2 1 Lycopene cyclase protein Eno-Rase_NADH_b PF12242.3 KZN90861.1 - 0.0068 16.1 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_2 PF07992.9 KZN90861.1 - 0.011 15.6 0.7 0.02 14.7 0.5 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN90861.1 - 0.054 12.3 6.4 0.094 11.5 4.4 1.3 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 KZN90861.1 - 0.055 12.2 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.1 KZN90861.1 - 0.11 12.5 4.5 0.27 11.3 3.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN90861.1 - 0.13 12.7 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN90861.1 - 0.14 10.5 2.2 14 3.9 2.1 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KZN90861.1 - 0.66 8.7 5.3 1.3 7.8 3.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN90861.1 - 2 6.9 6.1 12 4.3 0.0 3.1 2 1 1 3 3 3 0 Tryptophan halogenase Cupin_2 PF07883.6 KZN90862.1 - 6.1e-26 89.7 0.3 3.3e-15 55.3 0.1 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KZN90862.1 - 5.3e-06 26.1 0.2 0.018 14.7 0.1 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.3 KZN90862.1 - 2.6e-05 24.1 0.0 0.00024 21.0 0.0 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_3 PF05899.7 KZN90862.1 - 0.0004 19.7 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KZN90862.1 - 0.0016 17.8 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 Cupin ARD PF03079.9 KZN90862.1 - 0.013 15.4 0.2 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 ARD/ARD' family ArsB PF02040.10 KZN90863.1 - 1.1e-11 44.3 25.6 1.1e-06 27.8 8.2 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein WSK PF03832.8 KZN90863.1 - 0.12 11.7 0.4 0.35 10.2 0.3 1.8 1 0 0 1 1 1 0 WSK motif PMSI1 PF15322.1 KZN90864.1 - 0.0034 16.5 0.1 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative Fungal_trans PF04082.13 KZN90865.1 - 1e-28 99.9 0.0 1.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90865.1 - 2.5e-11 43.2 5.3 4.3e-11 42.5 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 KZN90866.1 - 8.9e-09 35.0 0.4 1.6e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN90866.1 - 1.6e-06 28.0 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 KZN90867.1 - 1.3e-12 47.1 31.5 1.3e-12 47.1 21.9 3.5 2 2 1 3 3 3 2 Major Facilitator Superfamily ELFV_dehydrog PF00208.16 KZN90869.1 - 6e-84 281.4 3.9 7.4e-84 281.1 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KZN90869.1 - 2.1e-48 163.1 0.0 3.7e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Med5 PF08689.5 KZN90870.1 - 0 1070.6 0.0 0 1070.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 ABC2_membrane PF01061.19 KZN90871.1 - 6.6e-84 280.2 49.9 2.4e-46 157.5 10.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN90871.1 - 1e-37 129.5 0.0 5e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN90871.1 - 1.7e-31 107.9 5.5 1.6e-29 101.5 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KZN90871.1 - 3.9e-07 29.4 32.5 8.1e-05 21.8 7.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KZN90871.1 - 1.6e-06 27.6 0.1 0.002 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KZN90871.1 - 3.3e-05 24.0 0.1 0.083 13.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN90871.1 - 0.00013 22.0 0.3 0.036 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KZN90871.1 - 0.00026 20.8 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KZN90871.1 - 0.00056 19.4 0.3 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KZN90871.1 - 0.0007 18.8 0.0 0.0054 15.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 KZN90871.1 - 0.00084 19.3 0.3 0.36 10.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KZN90871.1 - 0.00097 19.9 0.0 0.74 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN90871.1 - 0.0022 17.4 0.9 0.082 12.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KZN90871.1 - 0.0026 18.0 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN90871.1 - 0.0096 15.5 0.5 2.3 7.8 0.1 2.3 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 KZN90871.1 - 0.014 14.8 1.0 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 KZN90871.1 - 0.03 14.0 0.4 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 KZN90871.1 - 0.045 13.4 0.0 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 KZN90871.1 - 0.051 12.4 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.1 KZN90871.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KZN90871.1 - 0.16 11.6 0.3 5.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KZN90871.1 - 0.17 12.4 0.1 2.9 8.3 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein Zeta_toxin PF06414.7 KZN90871.1 - 0.17 10.9 0.0 5.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin HTH_32 PF13565.1 KZN90872.1 - 4.5e-05 24.1 3.0 0.0021 18.7 0.7 2.1 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 KZN90872.1 - 9.3e-05 22.5 0.2 0.00017 21.6 0.1 1.5 1 1 1 2 2 2 1 Winged helix-turn helix RasGEF PF00617.14 KZN90873.1 - 2.6e-55 187.0 0.7 5.6e-55 185.9 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KZN90873.1 - 5e-19 68.3 0.0 1.4e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KZN90873.1 - 1.9e-06 27.3 0.0 3.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN90873.1 - 2.1e-05 23.8 0.0 4.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HATPase_c_3 PF13589.1 KZN90874.1 - 1.4e-17 63.6 0.0 2.6e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KZN90874.1 - 4.7e-06 26.2 0.0 9.6e-05 22.0 0.0 2.7 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KZN90874.1 - 9.8e-06 25.2 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase p450 PF00067.17 KZN90876.1 - 6e-45 153.6 0.0 8.1e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAN_4 PF14295.1 KZN90879.1 - 1.1e-05 25.0 1.3 1.1e-05 25.0 0.9 3.6 3 0 0 3 3 2 2 PAN domain Pox_A_type_inc PF04508.7 KZN90879.1 - 0.0034 17.0 3.3 0.0086 15.7 0.2 3.0 1 1 1 2 2 2 1 Viral A-type inclusion protein repeat PAN_3 PF08277.7 KZN90879.1 - 0.008 15.7 4.2 0.016 14.7 0.1 2.9 2 0 0 2 2 2 1 PAN-like domain DUF2968 PF11180.3 KZN90879.1 - 0.022 14.1 7.6 0.035 13.4 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SlyX PF04102.7 KZN90879.1 - 0.027 14.8 0.5 0.072 13.4 0.3 1.8 1 1 0 1 1 1 0 SlyX Macoilin PF09726.4 KZN90879.1 - 0.031 12.5 13.0 0.036 12.3 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KZN90879.1 - 0.052 13.4 15.6 0.087 12.7 10.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 KZN90879.1 - 0.055 13.0 16.0 0.085 12.3 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4164 PF13747.1 KZN90879.1 - 0.11 12.6 10.1 0.18 11.9 6.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3584 PF12128.3 KZN90879.1 - 0.11 9.7 16.5 0.17 9.1 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 KZN90879.1 - 0.13 11.2 19.9 0.2 10.6 13.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Bacillus_HBL PF05791.6 KZN90879.1 - 0.25 10.6 3.4 0.43 9.9 2.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.6 KZN90879.1 - 0.26 9.9 13.0 0.37 9.4 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF342 PF03961.8 KZN90879.1 - 0.28 9.5 6.1 0.4 9.0 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 KZN90879.1 - 0.39 10.1 9.6 0.74 9.2 6.7 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Effector_1 PF04518.7 KZN90879.1 - 0.6 9.0 8.0 0.068 12.1 2.2 1.7 2 0 0 2 2 2 0 Effector from type III secretion system Exonuc_VII_L PF02601.10 KZN90879.1 - 0.94 8.5 5.3 1.4 8.0 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 KZN90879.1 - 1.8 8.5 6.4 2.6 7.9 4.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 KZN90879.1 - 4.7 7.4 10.6 6.5 7.0 7.4 1.3 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KZN90880.1 - 4.8e-22 78.0 0.1 1.5e-13 50.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN90880.1 - 2.1e-17 62.7 0.2 8.3e-09 35.4 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN90880.1 - 1.1e-16 59.7 0.1 1.7e-05 24.3 0.1 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KZN90880.1 - 4.7e-15 54.1 0.0 3.7e-05 23.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KZN90880.1 - 3.3e-14 52.9 0.4 4.4e-06 27.0 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 KZN90880.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Dyp_perox PF04261.7 KZN90882.1 - 4.9e-12 45.2 0.1 5.9e-09 35.1 0.0 3.2 3 0 0 3 3 3 2 Dyp-type peroxidase family bZIP_2 PF07716.10 KZN90883.1 - 2.8e-13 49.4 12.0 7.7e-13 48.0 8.3 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KZN90883.1 - 3.6e-07 30.0 7.0 7.4e-07 29.0 4.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor Macoilin PF09726.4 KZN90883.1 - 0.0042 15.4 0.9 0.0049 15.2 0.6 1.2 1 0 0 1 1 1 1 Transmembrane protein Inhibitor_I34 PF10466.4 KZN90883.1 - 0.18 11.8 4.3 5.3 7.1 0.4 2.5 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 DUF3260 PF11658.3 KZN90883.1 - 1.5 6.8 4.3 0.22 9.6 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) DDRGK PF09756.4 KZN90883.1 - 4.9 6.5 15.3 0.61 9.4 7.8 1.4 2 0 0 2 2 2 0 DDRGK domain DUF4094 PF13334.1 KZN90883.1 - 9.6 6.6 8.6 0.7 10.3 1.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Methyltransf_23 PF13489.1 KZN90884.1 - 0.044 13.5 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KZN90884.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 KZN90884.1 - 0.08 13.5 0.1 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KZN90884.1 - 0.18 11.3 0.2 0.45 10.1 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 KZN90885.1 - 4.7e-39 134.1 41.2 4.7e-39 134.1 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN90885.1 - 1.2e-13 50.4 8.7 1.2e-13 50.4 6.0 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans_2 PF11951.3 KZN90886.1 - 2.6e-07 29.5 0.1 3.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KZN90887.1 - 1.5e-23 83.7 0.0 1.8e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN90887.1 - 9.4e-23 80.9 0.3 1.1e-22 80.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN90887.1 - 2.5e-12 46.8 0.1 3.1e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN90887.1 - 0.0009 18.7 0.2 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.1 KZN90888.1 - 7.2e-15 54.7 0.0 1.8e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN90888.1 - 0.002 17.9 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KZN90888.1 - 0.0031 16.6 0.0 0.049 12.6 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 KZN90888.1 - 0.014 14.2 0.1 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN90888.1 - 0.03 14.7 0.2 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN90888.1 - 0.048 12.5 0.0 0.14 11.0 0.0 1.7 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KZN90888.1 - 0.067 13.0 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CENP-N PF05238.8 KZN90889.1 - 1.2e-131 439.4 0.0 1.4e-131 439.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Prok-RING_1 PF14446.1 KZN90890.1 - 8.2e-06 25.4 7.7 8.3e-06 25.4 2.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 KZN90890.1 - 2.1e-05 24.2 8.7 2.1e-05 24.2 6.0 2.4 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 KZN90890.1 - 0.00027 20.8 8.1 0.00027 20.8 5.6 2.2 2 1 0 2 2 2 1 FANCL C-terminal domain SWIM PF04434.12 KZN90890.1 - 0.0018 17.7 0.5 0.0018 17.7 0.3 1.7 2 0 0 2 2 1 1 SWIM zinc finger HypA PF01155.14 KZN90890.1 - 0.002 17.7 2.3 0.018 14.7 0.2 2.3 1 1 1 2 2 2 1 Hydrogenase expression/synthesis hypA family Rtf2 PF04641.7 KZN90890.1 - 0.046 12.9 0.3 0.062 12.4 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Cytochrom_CIII PF02085.11 KZN90890.1 - 0.093 12.8 6.3 0.16 12.0 4.4 1.3 1 0 0 1 1 1 0 Class III cytochrome C family PHD PF00628.24 KZN90890.1 - 0.16 11.6 9.5 0.38 10.4 6.5 1.7 1 1 0 1 1 1 0 PHD-finger zinc-ribbons_6 PF07191.7 KZN90890.1 - 0.17 11.6 5.4 0.69 9.7 3.7 2.0 1 1 0 1 1 1 0 zinc-ribbons PHF5 PF03660.9 KZN90890.1 - 0.18 11.8 4.7 0.41 10.7 0.5 2.1 2 0 0 2 2 2 0 PHF5-like protein zf-Apc11 PF12861.2 KZN90890.1 - 0.2 11.5 8.8 0.037 13.8 2.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 KZN90890.1 - 0.36 10.6 6.1 0.97 9.2 4.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.1 KZN90890.1 - 1.6 8.5 17.7 0.76 9.5 7.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain OrfB_Zn_ribbon PF07282.6 KZN90890.1 - 2.7 7.7 7.0 1.7 8.3 1.9 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF2318 PF10080.4 KZN90890.1 - 6.4 6.5 7.6 8.6 6.1 1.0 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-C3HC4_2 PF13923.1 KZN90890.1 - 9.8 6.2 14.2 0.19 11.7 4.2 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF974 PF06159.8 KZN90891.1 - 1.3e-76 257.3 0.0 1.6e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 KZN90892.1 - 3.4e-57 193.1 0.2 5.9e-57 192.3 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KZN90892.1 - 3.6e-18 65.3 0.5 7.7e-18 64.3 0.4 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KZN90892.1 - 1.9e-16 59.7 0.4 4.4e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 uDENN domain C1_1 PF00130.17 KZN90892.1 - 1.6e-05 24.4 7.2 3e-05 23.6 5.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KZN90892.1 - 0.00074 19.4 8.9 0.0014 18.6 2.6 2.4 1 1 1 2 2 2 1 C1-like domain SPA PF08616.5 KZN90892.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis C1_2 PF03107.11 KZN90892.1 - 0.013 15.5 3.9 0.03 14.4 2.7 1.6 1 0 0 1 1 1 0 C1 domain FDF PF09532.5 KZN90892.1 - 0.1 13.1 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 FDF domain PHD PF00628.24 KZN90892.1 - 0.18 11.4 9.5 0.053 13.2 3.3 2.3 1 1 1 2 2 2 0 PHD-finger DHquinase_I PF01487.10 KZN90893.1 - 2e-59 200.9 0.0 2.7e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase FMN_bind_2 PF04299.7 KZN90894.1 - 1.4e-43 148.3 0.0 7.1e-37 126.5 0.0 2.4 2 0 0 2 2 2 2 Putative FMN-binding domain Fungal_trans PF04082.13 KZN90895.1 - 2.1e-21 75.9 0.0 4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90895.1 - 2.1e-06 27.5 16.8 4.9e-06 26.3 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KZN90895.1 - 1.1 8.0 3.7 1.9 7.2 2.6 1.3 1 0 0 1 1 1 0 Clusterin Acyl_transf_1 PF00698.16 KZN90896.1 - 1.1e-30 107.1 0.2 1.3e-30 106.8 0.2 1.2 1 0 0 1 1 1 1 Acyl transferase domain Peripla_BP_6 PF13458.1 KZN90896.1 - 0.042 13.1 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein 2-Hacid_dh_C PF02826.14 KZN90897.1 - 2.6e-44 150.5 0.0 3.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KZN90897.1 - 4.3e-05 22.9 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.16 KZN90897.1 - 0.0005 19.7 0.0 0.00073 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 KZN90897.1 - 0.005 17.1 0.0 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 KZN90897.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 KZN90897.1 - 0.051 13.4 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KZN90897.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cu_amine_oxid PF01179.15 KZN90898.1 - 1.3e-170 567.6 0.0 1.6e-170 567.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KZN90898.1 - 1.2e-17 63.8 0.0 3.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KZN90898.1 - 5.7e-16 58.3 0.1 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldedh PF00171.17 KZN90899.1 - 1e-183 610.9 0.4 1.1e-183 610.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KZN90899.1 - 0.068 12.3 0.0 0.58 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease_2 PF13520.1 KZN90900.1 - 6.9e-55 186.2 49.5 8.3e-55 186.0 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN90900.1 - 1.2e-23 83.2 38.9 1.6e-23 82.7 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 KZN90900.1 - 0.069 13.0 1.5 0.89 9.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Kelch_5 PF13854.1 KZN90901.1 - 1.5e-17 63.1 8.9 1.7e-15 56.5 0.7 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KZN90901.1 - 1.5e-06 27.6 2.9 0.0091 15.5 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 KZN90901.1 - 0.00076 19.5 2.4 0.029 14.5 0.2 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 KZN90901.1 - 0.0015 18.6 10.6 0.036 14.2 0.3 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 KZN90901.1 - 0.0025 17.5 12.7 0.47 10.2 0.1 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF1517 PF07466.6 KZN90901.1 - 0.0048 15.9 0.3 0.013 14.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 KZN90901.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KZN90901.1 - 0.32 10.3 2.2 0.7 9.2 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M20 PF01546.23 KZN90903.1 - 1.2e-20 73.8 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN90903.1 - 4e-13 49.0 0.1 1.9e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain zf-RING_2 PF13639.1 KZN90903.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Ring finger domain GATase PF00117.23 KZN90904.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF2321 PF10083.4 KZN90904.1 - 0.0023 17.4 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) SNO PF01174.14 KZN90904.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family HAD_2 PF13419.1 KZN90905.1 - 1.8e-27 96.7 0.1 2.4e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AA_permease PF00324.16 KZN90906.1 - 6.8e-109 364.3 40.7 8.2e-109 364.0 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN90906.1 - 1.2e-30 106.4 41.9 1.7e-30 105.9 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 KZN90907.1 - 1.8e-09 37.3 8.9 4.3e-09 36.1 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAM_LAG1_CLN8 PF03798.11 KZN90908.1 - 7e-31 107.3 18.7 7e-31 107.3 13.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KZN90908.1 - 3.1e-21 74.6 0.3 8e-21 73.3 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein BRO1 PF03097.13 KZN90909.1 - 5.9e-115 384.0 0.0 1.1e-114 383.1 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KZN90909.1 - 5.9e-83 278.2 4.9 1.1e-82 277.3 3.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SET PF00856.23 KZN90910.1 - 7.4e-16 58.8 0.1 1.5e-15 57.8 0.1 1.5 1 1 0 1 1 1 1 SET domain Mito_carr PF00153.22 KZN90911.1 - 5e-45 151.1 3.8 9.9e-18 63.6 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Thiolase_C PF02803.13 KZN90912.1 - 2.5e-12 46.3 0.7 5.1e-11 42.0 0.5 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KZN90912.1 - 1.4e-07 31.0 0.1 8.9e-06 25.2 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KZN90912.1 - 5.8e-06 25.4 0.4 2.1e-05 23.6 0.1 2.1 1 1 1 2 2 2 1 Thiolase, N-terminal domain SpoVAD PF07451.6 KZN90912.1 - 0.0041 15.6 0.2 0.02 13.3 0.1 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 KZN90912.1 - 0.031 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KZN90912.1 - 0.066 13.0 0.1 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3431 PF11913.3 KZN90913.1 - 1.9e-73 246.6 0.0 2.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PT PF04886.7 KZN90914.1 - 0.022 14.0 3.8 0.022 14.0 2.6 2.3 2 0 0 2 2 2 0 PT repeat TAF4 PF05236.9 KZN90914.1 - 0.039 13.2 4.4 0.045 13.0 3.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PEARLI-4 PF05278.7 KZN90914.1 - 0.075 12.4 1.9 0.1 11.9 1.3 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Peptidase_S49_N PF08496.5 KZN90914.1 - 0.081 12.7 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDV3 PF15359.1 KZN90914.1 - 0.11 12.5 2.9 0.15 12.1 2.0 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Neur_chan_memb PF02932.11 KZN90914.1 - 0.12 12.1 0.3 0.14 12.0 0.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Menin PF05053.8 KZN90914.1 - 1.8 6.6 4.3 2.1 6.4 3.0 1.1 1 0 0 1 1 1 0 Menin SMN PF06003.7 KZN90915.1 - 4.4e-07 29.2 6.9 4.1e-05 22.8 0.7 2.1 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.17 KZN90916.1 - 1.2e-13 50.5 0.0 2.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90916.1 - 2.7e-09 36.8 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90916.1 - 6.5e-08 32.3 0.2 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHD5 PF04420.9 KZN90917.1 - 5e-63 211.5 3.7 6.5e-63 211.1 2.6 1.1 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.17 KZN90918.1 - 6e-06 25.3 3.6 0.13 11.6 0.7 3.8 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.9 KZN90919.1 - 2.2e-09 37.8 3.9 2.2e-09 37.8 2.7 2.2 2 0 0 2 2 2 1 4F5 protein family TRAM_LAG1_CLN8 PF03798.11 KZN90921.1 - 2.2e-39 135.0 20.8 2.2e-39 135.0 14.4 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KZN90921.1 - 5.4e-20 70.6 0.0 1.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein Abhydrolase_6 PF12697.2 KZN90922.1 - 0.00093 19.1 0.3 0.88 9.4 0.1 3.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family MFS_1 PF07690.11 KZN90923.1 - 2e-16 59.6 38.1 2e-16 59.6 26.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN90923.1 - 3.7e-07 28.7 8.9 3.7e-07 28.7 6.2 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HrpB7 PF09486.5 KZN90924.1 - 0.025 14.5 5.2 0.38 10.6 0.8 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Cortex-I_coil PF09304.5 KZN90924.1 - 0.03 14.3 2.0 0.053 13.5 0.4 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3584 PF12128.3 KZN90924.1 - 0.031 11.6 1.6 0.035 11.4 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HR1 PF02185.11 KZN90924.1 - 0.064 12.9 2.6 0.091 12.5 1.8 1.3 1 0 0 1 1 1 0 Hr1 repeat DUF972 PF06156.8 KZN90924.1 - 0.1 12.9 2.5 4.2 7.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) BCAS2 PF05700.6 KZN90924.1 - 0.18 11.2 2.2 0.22 10.9 1.5 1.0 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Caps_synth_GfcC PF06251.6 KZN90924.1 - 0.33 10.0 2.2 0.37 9.9 1.5 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC DUF1409 PF07197.7 KZN90924.1 - 0.52 10.4 4.0 1.2 9.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) DUF3585 PF12130.3 KZN90924.1 - 0.99 9.2 5.5 1.2 8.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) DUF4200 PF13863.1 KZN90924.1 - 1.6 8.7 5.0 4.6 7.2 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.6 KZN90924.1 - 4.8 7.6 8.0 20 5.6 4.2 2.8 1 1 1 2 2 2 0 MerR, DNA binding Zn_clus PF00172.13 KZN90925.1 - 9.4e-06 25.4 9.8 2.1e-05 24.3 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F17 PF04767.7 KZN90925.1 - 0.72 10.1 3.7 1.5 9.1 2.6 1.4 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Rad10 PF03834.9 KZN90926.1 - 2.2e-31 107.3 0.0 3.5e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.18 KZN90926.1 - 0.00041 19.8 0.0 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KZN90926.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KZN90926.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 KZN90927.1 - 1.3e-59 197.7 0.1 1.2e-20 72.9 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90927.1 - 5.8e-41 138.3 0.0 3e-12 46.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90927.1 - 8.1e-22 76.8 0.1 7.6e-10 38.4 0.0 4.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Atg14 PF10186.4 KZN90927.1 - 1.5 7.7 7.2 0.055 12.4 0.9 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cyt-b5 PF00173.23 KZN90928.1 - 1.1e-10 41.1 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AA_permease PF00324.16 KZN90929.1 - 1.9e-93 313.4 33.0 2.4e-93 313.0 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN90929.1 - 4.7e-15 55.0 33.4 6.5e-15 54.5 23.2 1.2 1 0 0 1 1 1 1 Amino acid permease CAF-1_p150 PF11600.3 KZN90930.1 - 2.8 7.2 8.6 1.7 8.0 0.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cupin_8 PF13621.1 KZN90931.1 - 4.6e-22 78.7 0.0 9.9e-22 77.6 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Pyr_redox_3 PF13738.1 KZN90932.1 - 5.2e-23 82.1 0.1 2.2e-22 80.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN90932.1 - 6.6e-08 31.2 0.3 5.4e-07 28.1 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN90932.1 - 1.3e-07 30.8 0.1 7.3e-06 25.1 0.1 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN90932.1 - 4.7e-07 29.7 0.1 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KZN90932.1 - 0.0033 16.5 0.1 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Fungal_trans PF04082.13 KZN90933.1 - 1.2e-20 73.4 0.1 2.3e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90933.1 - 8.2e-08 32.0 13.4 1.4e-07 31.3 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK_II_beta PF01214.13 KZN90934.1 - 8e-78 260.1 0.0 1.7e-77 259.1 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KZN90934.1 - 0.012 16.2 7.3 0.012 16.2 5.1 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 KZN90934.1 - 6.9 5.7 6.1 4.3 6.3 2.7 1.7 2 0 0 2 2 2 0 Myc amino-terminal region bZIP_1 PF00170.16 KZN90935.1 - 0.00014 21.7 8.9 0.00026 20.8 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN90935.1 - 0.0041 16.8 8.2 0.007 16.1 5.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KZN90935.1 - 0.023 14.9 2.4 0.057 13.7 1.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4616 PF15394.1 KZN90935.1 - 0.028 13.4 2.2 0.038 13.0 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) DUF1777 PF08648.7 KZN90935.1 - 5.8 6.5 14.0 8 6.1 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Aminotran_4 PF01063.14 KZN90936.1 - 2.7e-30 105.5 0.0 3.7e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 KZN90937.1 - 1.1e-17 64.0 0.0 2.5e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90937.1 - 7e-09 35.1 0.0 2.8e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3433 PF11915.3 KZN90937.1 - 0.065 13.3 0.0 0.36 11.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3433) Peptidase_M49 PF03571.10 KZN90938.1 - 3.1e-231 768.2 0.0 3.7e-231 768.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 PRA-PH PF01503.12 KZN90938.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase SNF5 PF04855.7 KZN90940.1 - 3.6e-87 291.8 0.0 4.9e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 KZN90940.1 - 1.1e-05 24.7 1.1 3.1e-05 23.2 0.7 1.9 1 0 0 1 1 1 1 GATA zinc finger DUF4336 PF14234.1 KZN90941.1 - 2.9e-17 62.7 0.0 7.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.18 KZN90942.1 - 1.7e-19 70.0 11.9 2.2e-19 69.7 8.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF308 PF03729.8 KZN90942.1 - 0.024 14.6 0.3 0.024 14.6 0.2 3.7 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) MpPF26 PF07666.6 KZN90942.1 - 0.096 12.5 1.3 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 PepSY_TM_2 PF13703.1 KZN90942.1 - 0.35 11.0 12.4 0.12 12.5 0.7 3.3 1 1 2 3 3 3 0 PepSY-associated TM helix DUF4381 PF14316.1 KZN90942.1 - 3.4 7.7 5.1 3.3 7.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) phiKZ_IP PF12699.2 KZN90943.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Porphobil_deam PF01379.15 KZN90944.1 - 3.2e-75 251.7 0.0 6.9e-75 250.6 0.0 1.5 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KZN90944.1 - 1.3e-19 70.0 0.2 4.7e-19 68.2 0.1 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Hydantoinase_B PF02538.9 KZN90945.1 - 5.3e-173 576.0 0.3 7.2e-173 575.5 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KZN90945.1 - 2.5e-90 302.5 0.0 1.2e-89 300.2 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KZN90945.1 - 6e-55 185.4 0.0 2e-53 180.5 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region EVE PF01878.13 KZN90945.1 - 0.16 11.9 0.2 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 EVE domain MFS_1 PF07690.11 KZN90946.1 - 2.3e-25 89.0 32.4 2.3e-25 89.0 22.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 KZN90946.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF485 PF04341.7 KZN90946.1 - 0.36 10.5 6.8 0.19 11.4 1.9 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF485 DIOX_N PF14226.1 KZN90947.1 - 1e-15 58.2 0.0 1.6e-13 51.2 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN90947.1 - 1.2e-12 47.9 0.1 2.7e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.3 KZN90948.1 - 3.2e-52 177.4 6.3 4.3e-52 177.0 4.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain LCCL PF03815.14 KZN90949.1 - 2.7e-21 75.3 0.0 4.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Metallophos PF00149.23 KZN90950.1 - 2.2e-10 40.2 0.0 7.3e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN90950.1 - 1.6e-07 31.2 0.2 3.9e-07 30.0 0.1 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Cupin_3 PF05899.7 KZN90950.1 - 5.4e-06 25.6 0.2 1.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 KZN90950.1 - 0.0037 16.8 0.0 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ ThiF PF00899.16 KZN90951.1 - 1.8e-34 118.5 0.0 3e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 KZN90951.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KZN90951.1 - 0.013 15.5 0.2 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 KZN90951.1 - 0.051 12.5 0.3 0.25 10.2 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KZN90951.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KZN90951.1 - 0.06 12.2 1.9 0.09 11.6 0.1 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KZN90951.1 - 0.092 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KZN90951.1 - 0.14 11.5 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_17 PF00332.13 KZN90951.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 AA_permease_2 PF13520.1 KZN90952.1 - 1e-45 156.0 35.1 1.4e-45 155.6 24.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN90952.1 - 4.3e-15 55.0 29.1 6.1e-15 54.5 20.2 1.1 1 0 0 1 1 1 1 Amino acid permease Mac PF12464.3 KZN90953.1 - 1.5e-12 47.2 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KZN90953.1 - 4.7e-12 44.8 5.0 2.2e-09 36.3 2.4 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KZN90953.1 - 7.9e-12 44.5 4.1 3.1e-09 36.2 1.4 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Acetyltransf_11 PF13720.1 KZN90953.1 - 0.16 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Abhydrolase_1 PF00561.15 KZN90954.1 - 8.6e-19 68.0 0.0 9.2e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN90954.1 - 6.6e-13 49.0 0.7 2e-11 44.1 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KZN90954.1 - 0.00061 19.2 0.1 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Gly_transf_sug PF04488.10 KZN90956.1 - 2e-12 47.4 0.0 3.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FAD_binding_4 PF01565.18 KZN90958.1 - 4.6e-19 68.2 1.1 9.3e-19 67.2 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN90958.1 - 1.1e-11 44.4 1.3 2.4e-11 43.3 0.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like DapB_N PF01113.15 KZN90958.1 - 0.01 15.7 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pkinase PF00069.20 KZN90959.1 - 1.7e-63 214.2 0.0 2.2e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90959.1 - 2.1e-36 125.3 0.0 2.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN90959.1 - 0.0055 15.7 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN90959.1 - 0.0059 15.5 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN90959.1 - 0.017 14.8 0.1 0.11 12.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KZN90959.1 - 0.052 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_C PF00137.16 KZN90960.1 - 2e-18 66.0 19.8 2.5e-14 52.9 6.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ApbE PF02424.10 KZN90960.1 - 0.12 11.6 0.4 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 ApbE family G0-G1_switch_2 PF15103.1 KZN90960.1 - 6.1 7.1 5.5 8.7 6.6 0.7 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 SDF PF00375.13 KZN90960.1 - 6.2 5.4 15.1 1.1 7.8 8.0 1.5 1 1 1 2 2 2 0 Sodium:dicarboxylate symporter family DUF3816 PF12822.2 KZN90960.1 - 7.1 6.4 13.0 8.5 6.2 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) CNH PF00780.17 KZN90961.1 - 2.4e-82 276.4 0.0 4.7e-82 275.4 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KZN90961.1 - 3.7e-43 146.6 0.0 9.2e-43 145.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KZN90961.1 - 9e-37 126.6 0.0 1.7e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KZN90961.1 - 1.3e-12 47.2 0.0 3.5e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1833 PF08875.6 KZN90961.1 - 0.098 11.8 0.1 0.24 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Septin PF00735.13 KZN90962.1 - 9e-102 339.8 0.5 1.6e-101 339.0 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KZN90962.1 - 0.00026 20.9 0.0 0.00061 19.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KZN90962.1 - 0.00089 18.4 0.1 0.0024 17.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KZN90962.1 - 0.0035 16.8 1.4 0.044 13.2 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KZN90962.1 - 0.011 15.5 7.0 0.88 9.3 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 KZN90962.1 - 0.02 15.3 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein IIGP PF05049.8 KZN90962.1 - 0.056 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 KZN90962.1 - 0.064 13.4 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 KZN90962.1 - 0.069 12.2 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.13 KZN90962.1 - 0.32 10.4 0.1 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KZN90962.1 - 0.44 11.3 5.7 0.46 11.3 0.2 2.9 2 2 0 2 2 2 0 AAA domain WD40 PF00400.27 KZN90963.1 - 1.1e-08 34.6 2.6 0.0025 17.6 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KZN90963.1 - 0.0027 17.1 0.0 2.7 7.5 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 KZN90963.1 - 0.0067 15.5 0.0 0.31 10.0 0.0 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KZN90963.1 - 0.014 13.2 0.0 0.033 11.9 0.0 1.5 1 1 1 2 2 2 0 IKI3 family RRM_1 PF00076.17 KZN90964.1 - 4.3e-20 71.1 0.0 1.1e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90964.1 - 7.3e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90964.1 - 8.6e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KZN90964.1 - 0.06 12.8 1.2 0.49 9.9 0.0 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain DLIC PF05783.6 KZN90965.1 - 2e-37 129.0 0.0 9.3e-36 123.4 0.0 2.8 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) Spermine_synth PF01564.12 KZN90966.1 - 5.5e-09 35.3 0.0 9.7e-09 34.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_30 PF05430.6 KZN90966.1 - 0.051 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 KZN90966.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2052 PF09747.4 KZN90967.1 - 2.4e-32 112.3 9.8 9e-32 110.4 6.8 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.23 KZN90968.1 - 1.9e-94 316.4 0.0 2.3e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN90968.1 - 1.8e-16 60.8 0.1 6e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SET PF00856.23 KZN90969.1 - 7.9e-08 32.7 3.8 9.6e-07 29.2 0.1 3.2 2 1 0 2 2 2 1 SET domain HC2 PF07382.6 KZN90969.1 - 7.4e-06 25.9 45.0 1.1e-05 25.3 31.2 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Spc7 PF08317.6 KZN90969.1 - 0.029 13.0 16.2 0.058 12.0 11.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec23_helical PF04815.10 KZN90969.1 - 0.3 10.5 13.2 0.92 8.9 2.4 2.7 1 1 1 2 2 2 0 Sec23/Sec24 helical domain LMBR1 PF04791.11 KZN90969.1 - 0.58 8.6 4.6 0.81 8.1 3.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Acetyltransf_11 PF13720.1 KZN90969.1 - 0.77 10.0 5.0 8.3 6.7 0.4 2.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Mitofilin PF09731.4 KZN90969.1 - 1.7 7.1 24.9 2.3 6.7 17.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.6 KZN90969.1 - 4.9 5.3 23.5 6.5 4.9 16.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Otopetrin PF03189.8 KZN90969.1 - 6.9 5.5 8.5 11 4.9 5.9 1.4 1 0 0 1 1 1 0 Otopetrin UBA_4 PF14555.1 KZN90970.1 - 4.6e-12 45.2 0.3 6.5e-11 41.5 0.2 2.5 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 KZN90970.1 - 0.073 12.6 3.9 0.075 12.6 0.5 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif SH3_1 PF00018.23 KZN90972.1 - 3.3e-09 35.9 0.1 6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KZN90972.1 - 4.9e-07 29.1 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KZN90972.1 - 3.8e-06 26.3 0.0 7.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MIG-14_Wnt-bd PF06664.7 KZN90972.1 - 0.042 12.6 2.1 0.063 12.1 1.5 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Bac_chlorC PF02043.12 KZN90972.1 - 0.78 9.5 2.9 0.9 9.3 0.6 2.2 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein ABC2_membrane_5 PF13346.1 KZN90972.1 - 7.3 5.8 18.0 12 5.1 12.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein APH PF01636.18 KZN90973.1 - 3.6e-22 79.2 0.0 4.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN90973.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KZN90973.1 - 0.011 15.0 0.0 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KZN90973.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Response_reg PF00072.19 KZN90974.1 - 6.1e-20 71.3 0.0 5.2e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain SH3_3 PF08239.6 KZN90975.1 - 0.00056 20.0 0.1 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain NLPC_P60 PF00877.14 KZN90975.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family Bot1p PF12298.3 KZN90976.1 - 4e-51 173.3 0.4 4e-51 173.3 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein PUL PF08324.6 KZN90977.1 - 1.4e-56 191.2 0.0 1.9e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KZN90977.1 - 1.8e-44 150.4 0.1 3.4e-44 149.5 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KZN90977.1 - 3.6e-42 140.7 13.8 8.2e-09 35.0 0.5 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KZN90977.1 - 0.0013 18.4 0.0 0.12 12.1 0.0 2.8 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region GCV_T_C PF08669.6 KZN90977.1 - 0.034 14.1 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain YjeF_N PF03853.10 KZN90978.1 - 6.4e-35 120.2 0.0 8e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 KZN90979.1 - 5.6e-25 86.8 0.1 6.8e-25 86.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 KZN90980.1 - 4.5e-16 58.2 0.0 5.7e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90980.1 - 7.3e-09 35.4 0.0 1.1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KZN90981.1 - 8.9e-34 114.1 10.6 1.2e-10 40.8 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 KZN90981.1 - 0.016 13.8 0.0 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 KZN90981.1 - 0.05 11.8 0.0 0.085 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain RRM_1 PF00076.17 KZN90982.1 - 3.2e-16 58.7 0.0 5.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN90982.1 - 1.8e-10 40.6 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN90982.1 - 2.2e-05 24.2 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KZN90982.1 - 3.4e-05 24.2 9.4 3.4e-05 24.2 6.5 4.4 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 CH PF00307.26 KZN90983.1 - 7.5e-37 125.6 0.0 2e-18 66.3 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KZN90983.1 - 1.5e-27 95.3 0.2 3.4e-27 94.1 0.1 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KZN90983.1 - 1.9e-09 37.0 2.0 5e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KZN90983.1 - 0.00054 19.6 0.1 0.004 16.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KZN90983.1 - 0.0023 17.1 0.1 0.02 14.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KZN90983.1 - 0.01 15.4 0.3 0.077 12.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.1 KZN90983.1 - 0.25 11.4 2.6 1.5 8.9 0.2 3.2 2 1 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.16 KZN90983.1 - 3.6 7.9 7.2 2.5 8.4 0.0 3.4 2 1 2 4 4 4 0 Spectrin repeat PhyH PF05721.8 KZN90984.1 - 6e-13 49.3 0.0 9.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.13 KZN90985.1 - 7.5e-10 38.1 0.0 1.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN90985.1 - 6.9e-06 25.8 6.6 1.3e-05 25.0 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KZN90986.1 - 1.2e-22 80.3 0.0 2.4e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN90986.1 - 8.6e-11 41.3 0.0 1.1e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PAR1 PF06521.6 KZN90986.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 PAR1 protein Gmad1 PF10647.4 KZN90986.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain CorA PF01544.13 KZN90987.1 - 1.6e-08 33.9 1.5 2.1e-08 33.5 1.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.16 KZN90988.1 - 4e-21 74.8 33.7 1e-12 47.1 4.9 3.8 1 1 1 2 2 2 2 Amino acid permease APH PF01636.18 KZN90989.1 - 7.3e-17 61.9 0.0 8.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN90989.1 - 6.2e-07 29.1 0.0 9.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KZN90989.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.6 KZN90989.1 - 0.054 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Aldo_ket_red PF00248.16 KZN90991.1 - 1.3e-48 165.2 0.0 1.6e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 KZN90991.1 - 0.13 11.5 0.3 3 7.2 0.2 2.6 2 0 0 2 2 2 0 Poliovirus 3A protein like ALMT PF11744.3 KZN90991.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Init_tRNA_PT PF04179.7 KZN90992.1 - 6.1e-134 447.2 0.0 4.4e-101 338.9 0.0 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 KZN90993.1 - 2.4e-15 57.2 0.0 3.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN90993.1 - 1.8e-07 30.7 0.1 3.4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN90993.1 - 3.8e-05 24.1 0.1 0.00038 20.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KZN90993.1 - 0.019 14.6 0.0 0.2 11.2 0.0 2.1 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase SIS PF01380.17 KZN90993.1 - 0.086 12.4 0.3 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 SIS domain NUDIX PF00293.23 KZN90994.1 - 1.2e-18 67.0 0.0 1.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 KZN90995.1 - 9.9e-05 22.0 0.0 0.00028 20.5 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain EST1_DNA_bind PF10373.4 KZN90996.1 - 4.7e-06 26.0 0.1 1.6e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Glycos_transf_2 PF00535.21 KZN90997.1 - 1.5e-20 73.5 0.0 1.2e-17 64.1 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KZN90997.1 - 3.7e-08 33.4 0.5 0.0079 16.0 0.0 3.6 1 1 3 4 4 4 2 Glycosyltransferase like family 2 Striatin PF08232.7 KZN90999.1 - 0.0019 18.5 1.0 0.0024 18.1 0.0 1.7 2 0 0 2 2 2 1 Striatin family HBS1_N PF08938.5 KZN90999.1 - 0.45 10.6 2.2 11 6.1 0.2 2.5 2 0 0 2 2 2 0 HBS1 N-terminus Autophagy_N PF03986.8 KZN91001.1 - 9.9e-50 168.1 0.0 2e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KZN91001.1 - 6.8e-22 77.4 0.2 1.5e-21 76.3 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KZN91001.1 - 2.1e-14 52.2 0.5 3.5e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal AAA_11 PF13086.1 KZN91002.1 - 1.7e-21 76.8 0.3 4.3e-21 75.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain zf-CCCH PF00642.19 KZN91002.1 - 5.6e-07 29.1 1.5 1e-06 28.2 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_12 PF13087.1 KZN91002.1 - 9.9e-07 28.3 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN91002.1 - 1.6e-06 27.7 0.1 5.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN91002.1 - 0.00044 19.8 0.2 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KZN91002.1 - 0.0034 16.4 0.0 0.0074 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) zf-CCCH_2 PF14608.1 KZN91002.1 - 0.7 9.9 2.7 1.6 8.8 1.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Cyclin_N PF00134.18 KZN91004.1 - 0.00058 19.4 0.0 0.12 11.9 0.0 2.6 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 KZN91004.1 - 0.00083 19.1 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF2856 PF11043.3 KZN91005.1 - 0.15 12.2 2.6 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) DUF3450 PF11932.3 KZN91005.1 - 0.21 10.8 7.9 0.3 10.3 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF812 PF05667.6 KZN91005.1 - 0.23 9.9 6.9 0.32 9.4 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IncA PF04156.9 KZN91005.1 - 0.32 10.5 6.1 0.49 9.9 4.2 1.2 1 0 0 1 1 1 0 IncA protein SPX PF03105.14 KZN91005.1 - 0.33 10.6 3.3 0.56 9.9 2.3 1.6 1 1 0 1 1 1 0 SPX domain DUF2570 PF10828.3 KZN91005.1 - 0.8 9.3 5.2 0.26 10.9 1.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) GAS PF13851.1 KZN91005.1 - 1.9 7.6 12.4 2.8 7.0 8.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SecY PF00344.15 KZN91006.1 - 1.2e-96 323.7 9.3 1.5e-96 323.4 6.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KZN91006.1 - 4.8e-18 64.3 0.3 1.5e-17 62.7 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ArgJ PF01960.13 KZN91007.1 - 6.5e-145 482.3 0.2 7.6e-145 482.1 0.1 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.9 KZN91008.1 - 4.5e-96 321.5 0.0 5.8e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.2 KZN91008.1 - 0.076 13.0 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain ORC6 PF05460.8 KZN91008.1 - 0.18 10.8 8.3 0.31 10.1 5.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.10 KZN91009.1 - 1.9e-11 44.1 0.3 3.4e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 FUN14 family DUF543 PF04418.7 KZN91009.1 - 0.0016 18.3 2.5 0.27 11.2 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF543) SOR_SNZ PF01680.12 KZN91010.1 - 9.9e-110 365.0 6.6 1.7e-109 364.2 4.6 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KZN91010.1 - 5.4e-09 35.4 7.0 2.2e-06 26.9 0.1 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KZN91010.1 - 0.00024 20.0 0.6 0.14 10.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KZN91010.1 - 0.00093 18.5 0.9 0.15 11.2 0.0 3.2 2 2 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 KZN91010.1 - 0.0018 17.4 0.1 0.043 12.8 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KZN91010.1 - 0.0064 15.4 1.0 0.14 11.1 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 KZN91010.1 - 0.018 14.1 0.4 0.018 14.1 0.3 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.1 KZN91010.1 - 0.032 13.4 3.6 0.3 10.2 0.2 3.0 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase IBN_N PF03810.14 KZN91011.1 - 0.00012 21.9 1.7 0.00032 20.5 1.0 2.0 1 1 0 1 1 1 1 Importin-beta N-terminal domain DUF577 PF04510.7 KZN91011.1 - 0.062 12.9 0.5 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF577) Phage_Coat_Gp8 PF05371.7 KZN91011.1 - 0.067 12.7 0.7 1.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Peptidase_M24 PF00557.19 KZN91012.1 - 5.2e-39 133.9 0.0 7.9e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KZN91012.1 - 1.7e-21 77.0 0.0 6.6e-20 71.9 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Nse4-Nse3_bdg PF15412.1 KZN91012.1 - 0.19 11.6 1.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Sec8_exocyst PF04048.9 KZN91013.1 - 2.5e-47 160.0 1.1 5.7e-47 158.9 0.8 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KZN91013.1 - 2.6e-09 36.4 0.4 5.1e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 KZN91013.1 - 0.00035 18.8 0.5 0.00072 17.8 0.3 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.7 KZN91013.1 - 0.024 13.1 1.9 0.042 12.3 1.3 1.3 1 0 0 1 1 1 0 Dor1-like family DPBB_1 PF03330.13 KZN91014.1 - 1.5e-09 37.7 0.1 5.4e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KZN91014.1 - 0.0038 16.9 0.1 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.16 KZN91014.1 - 0.0097 15.6 0.6 0.019 14.7 0.4 1.5 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.7 KZN91014.1 - 0.025 14.5 0.2 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 Cerato-platanin Mo-co_dimer PF03404.11 KZN91014.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Inhibitor_I9 PF05922.11 KZN91015.1 - 1.6e-10 41.4 0.1 1.9e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 HLH PF00010.21 KZN91016.1 - 1.3e-13 50.4 2.7 2.6e-13 49.4 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CN_hydrolase PF00795.17 KZN91017.1 - 1e-13 51.0 0.0 6.1e-13 48.5 0.0 2.0 1 1 0 2 2 2 1 Carbon-nitrogen hydrolase DUF3114 PF11311.3 KZN91017.1 - 0.039 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Pkinase PF00069.20 KZN91018.1 - 1.3e-20 73.6 0.0 1.1e-19 70.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91018.1 - 7e-09 35.1 0.1 0.00057 19.0 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase SAC3_GANP PF03399.11 KZN91019.1 - 2.1e-55 187.4 1.3 3.1e-55 186.9 0.9 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KZN91019.1 - 0.00012 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2841 PF11001.3 KZN91020.1 - 1.9e-46 157.0 0.0 4.2e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 KZN91021.1 - 7.9e-75 251.8 27.6 6.8e-39 133.9 6.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN91021.1 - 1.5e-51 174.3 0.0 6.4e-30 104.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN91021.1 - 7.2e-10 38.4 2.9 0.0043 16.3 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KZN91021.1 - 1.5e-06 28.3 0.5 0.031 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KZN91021.1 - 1.2e-05 25.4 1.8 1.2 9.0 0.0 4.8 5 0 0 5 5 5 1 AAA domain MMR_HSR1 PF01926.18 KZN91021.1 - 1.3e-05 25.1 0.0 0.22 11.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KZN91021.1 - 3e-05 23.5 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN91021.1 - 0.00015 20.9 0.6 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KZN91021.1 - 0.00022 20.6 0.3 0.92 9.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KZN91021.1 - 0.0014 18.4 0.6 1.2 8.9 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 KZN91021.1 - 0.0022 17.8 0.4 0.32 10.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KZN91021.1 - 0.0032 17.9 2.7 2.2 8.8 0.0 3.2 3 0 0 3 3 3 2 Miro-like protein AAA_23 PF13476.1 KZN91021.1 - 0.0059 16.9 0.2 0.74 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KZN91021.1 - 0.018 14.6 4.4 0.97 8.9 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 KZN91021.1 - 0.054 13.6 1.3 3.9 7.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN91021.1 - 0.061 14.1 0.0 8 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN91021.1 - 0.084 12.3 0.1 10 5.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KZN91021.1 - 0.095 11.7 0.1 7.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KZN91021.1 - 0.12 12.6 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KZN91021.1 - 0.14 11.9 0.7 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KZN91021.1 - 0.29 10.5 2.9 9.7 5.5 0.0 3.1 2 1 0 3 3 3 0 AAA-like domain NACHT PF05729.7 KZN91021.1 - 0.49 10.0 4.6 0.26 10.9 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Ank_2 PF12796.2 KZN91022.1 - 7.2e-25 87.1 0.0 9.2e-17 61.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN91022.1 - 2.5e-15 55.3 1.2 0.056 13.2 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KZN91022.1 - 3.7e-13 49.5 0.4 0.0023 18.3 0.0 6.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN91022.1 - 2.6e-11 42.6 2.5 0.053 13.7 0.0 6.9 6 2 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 KZN91022.1 - 1.3e-08 34.7 1.0 0.065 13.5 0.0 5.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN91024.1 - 1e-06 28.7 0.1 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KZN91024.1 - 0.00094 18.8 0.8 0.0026 17.5 0.5 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 KZN91024.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KZN91024.1 - 0.013 15.7 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 KZN91024.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Myb_DNA-bind_6 PF13921.1 KZN91025.1 - 1.9e-05 24.7 0.2 3.4e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN91025.1 - 5.6e-05 23.1 1.0 0.00015 21.7 0.7 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Adap_comp_sub PF00928.16 KZN91026.1 - 1.6e-85 286.4 0.0 1.9e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KZN91026.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KZN91026.1 - 0.006 15.7 0.1 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain p450 PF00067.17 KZN91027.1 - 3.9e-68 230.0 0.0 4.5e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4203 PF13886.1 KZN91028.1 - 4.1e-44 150.5 22.1 5.5e-44 150.1 15.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 KZN91028.1 - 1.8e-31 108.4 0.0 3.4e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SSB PF00436.20 KZN91029.1 - 9.1e-19 67.2 0.0 1.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 KZN91030.1 - 6e-101 337.2 15.1 7.4e-101 336.9 10.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Exo_endo_phos PF03372.18 KZN91032.1 - 2.2e-20 73.6 0.1 3.4e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 KZN91033.1 - 1.2e-18 67.3 0.0 1.7e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Dcp1-like decapping family DUF2305 PF10230.4 KZN91034.1 - 4.9e-81 272.0 0.0 5.7e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KZN91034.1 - 3e-06 27.2 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN91034.1 - 7.4e-05 22.5 0.0 0.00027 20.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN91034.1 - 0.0051 16.4 0.0 0.0094 15.5 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 KZN91034.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KZN91034.1 - 0.02 13.7 0.0 0.071 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF3089 PF11288.3 KZN91034.1 - 0.031 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LCAT PF02450.10 KZN91034.1 - 0.086 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SMK-1 PF04802.10 KZN91035.1 - 9.9e-76 253.5 0.3 1.9e-75 252.6 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 KZN91035.1 - 0.051 12.6 0.1 0.24 10.4 0.0 1.8 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D DUF914 PF06027.7 KZN91036.1 - 2.8e-104 348.6 18.7 3.7e-104 348.1 13.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KZN91036.1 - 3e-05 24.0 27.7 0.00017 21.6 7.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 KZN91036.1 - 0.011 15.4 3.4 0.011 15.4 2.3 2.5 2 0 0 2 2 2 0 Triose-phosphate Transporter family Zwint PF15556.1 KZN91037.1 - 0.2 10.8 3.4 0.29 10.3 2.4 1.1 1 0 0 1 1 1 0 ZW10 interactor PAP_assoc PF03828.14 KZN91038.1 - 2.6e-18 65.7 0.1 6.8e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KZN91038.1 - 8.7e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sigma54_AID PF00309.15 KZN91038.1 - 8.3 5.9 17.2 18 4.8 11.9 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) SE PF08491.5 KZN91039.1 - 2.1e-95 318.7 0.0 2.8e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KZN91039.1 - 2.9e-11 43.0 0.0 1.6e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN91039.1 - 3.8e-08 32.6 0.2 4e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN91039.1 - 0.00056 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KZN91039.1 - 0.001 19.4 0.2 0.0062 16.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN91039.1 - 0.0011 17.9 0.7 0.0018 17.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KZN91039.1 - 0.0027 16.6 0.1 0.062 12.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KZN91039.1 - 0.0041 16.0 0.3 0.042 12.7 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN91039.1 - 0.0052 16.7 0.7 0.011 15.7 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KZN91039.1 - 0.0073 15.4 0.3 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN91039.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KZN91039.1 - 0.017 14.5 0.3 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KZN91039.1 - 0.046 13.3 0.1 0.092 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KZN91039.1 - 0.097 11.1 0.3 0.16 10.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 KZN91039.1 - 0.098 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KZN91039.1 - 0.11 11.8 0.1 0.29 10.4 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KZN91039.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KZN91039.1 - 0.23 10.0 0.1 0.64 8.5 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase PPR_3 PF13812.1 KZN91040.1 - 1.5e-05 24.8 0.3 0.096 13.0 0.0 5.4 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 KZN91040.1 - 0.00022 21.1 0.7 0.079 12.9 0.0 4.0 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.15 KZN91040.1 - 0.002 17.9 2.2 0.22 11.6 0.0 4.2 5 0 0 5 5 5 1 PPR repeat Spo0A_C PF08769.6 KZN91040.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal MFS_1 PF07690.11 KZN91041.1 - 1.4e-23 83.2 40.6 6.7e-23 80.9 16.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91041.1 - 0.0049 15.4 23.0 0.048 12.2 15.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1751 PF08551.5 KZN91041.1 - 0.028 14.7 0.9 0.028 14.7 0.6 2.3 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Ferrochelatase PF00762.14 KZN91042.1 - 2.3e-92 309.3 0.0 2.7e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 KZN91043.1 - 3.5e-37 127.7 0.0 7.2e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KZN91043.1 - 4.3e-32 111.3 0.0 6.2e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KZN91043.1 - 2.4e-12 47.1 0.0 6.2e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KZN91043.1 - 1.9e-11 43.1 0.0 3.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain VWA PF00092.23 KZN91043.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 KZN91043.1 - 0.029 13.9 0.4 0.22 11.0 0.2 2.3 1 1 0 1 1 1 0 HeH/LEM domain VWA_2 PF13519.1 KZN91043.1 - 0.073 13.1 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF3431 PF11913.3 KZN91044.1 - 7.1e-87 290.5 0.2 1.1e-86 289.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-CCCH PF00642.19 KZN91045.1 - 1.2e-08 34.4 1.3 2.1e-08 33.6 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KZN91045.1 - 4.5e-08 32.9 9.6 7.9e-08 32.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN91045.1 - 6.1e-08 32.2 4.0 1e-07 31.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN91045.1 - 7.2e-07 28.9 7.0 1.2e-06 28.2 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN91045.1 - 7.7e-07 28.7 7.8 1.3e-06 28.0 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN91045.1 - 1.3e-06 27.9 9.5 2.3e-06 27.1 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KZN91045.1 - 0.0023 17.7 8.4 0.0045 16.8 5.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN91045.1 - 0.037 13.7 5.5 0.087 12.5 3.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KZN91045.1 - 0.039 13.4 2.2 0.075 12.5 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 KZN91045.1 - 0.14 12.5 3.5 0.32 11.3 0.5 2.7 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT Mcp5_PH PF12814.2 KZN91046.1 - 1.1e-42 144.7 0.1 2.7e-42 143.5 0.1 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Methyltransf_23 PF13489.1 KZN91047.1 - 2.9e-13 49.8 0.0 4.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN91047.1 - 8.3e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91047.1 - 2.7e-06 27.9 0.0 4.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN91047.1 - 4.3e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN91047.1 - 0.0029 17.2 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KZN91047.1 - 0.051 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2439 PF10382.4 KZN91048.1 - 1.4e-28 98.8 0.2 2.1e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.1 KZN91049.1 - 2e-17 62.5 0.2 4.5e-17 61.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN91049.1 - 1.9e-14 52.7 0.1 3.2e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KZN91049.1 - 6.3e-11 41.6 0.1 1e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 KZN91049.1 - 6.7e-09 35.5 0.4 1.1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 BAR domain Apolipoprotein PF01442.13 KZN91049.1 - 0.00031 20.3 0.8 0.0014 18.1 1.2 1.6 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain GAS PF13851.1 KZN91049.1 - 0.014 14.5 0.7 0.021 14.0 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding p450 PF00067.17 KZN91051.1 - 3.7e-50 170.8 0.0 5.2e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KZN91052.1 - 2.2e-13 50.6 0.0 5.3e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN91052.1 - 0.0004 19.9 0.0 0.00057 19.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN91052.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.9 KZN91052.1 - 0.081 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Alpha-amylase PF00128.19 KZN91053.1 - 1.4e-17 64.0 1.4 2.5e-16 59.9 0.9 2.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KZN91053.1 - 1.3e-14 54.2 0.1 2.3e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KZN91053.1 - 7e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KZN91053.1 - 3.1e-06 26.6 0.0 6.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 GST_N_2 PF13409.1 KZN91054.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KZN91054.1 - 6.1e-06 26.3 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN91054.1 - 0.00028 20.6 0.1 0.0007 19.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN91054.1 - 0.03 14.7 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN91054.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KZN91055.1 - 3.3e-24 85.1 1.0 7e-24 84.0 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91055.1 - 7.7e-06 25.7 8.7 1.8e-05 24.5 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KZN91056.1 - 5.1e-73 246.1 16.4 5.9e-73 245.9 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91056.1 - 8.7e-20 70.7 30.8 6.5e-17 61.2 9.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DAO PF01266.19 KZN91057.1 - 3.8e-41 141.1 0.0 9e-41 139.9 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN91057.1 - 0.00012 22.0 0.9 0.00025 21.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN91057.1 - 0.00072 19.4 0.0 0.024 14.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KZN91057.1 - 0.0041 17.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KZN91057.1 - 0.0044 16.1 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN91057.1 - 0.0083 16.5 0.0 0.029 14.7 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN91057.1 - 0.014 14.2 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN91057.1 - 0.12 12.1 0.0 1.7 8.3 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KZN91057.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KZN91057.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN91057.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KZN91057.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Glyco_hydro_3 PF00933.16 KZN91058.1 - 6.3e-87 291.3 0.0 8.9e-87 290.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN91058.1 - 5.3e-56 189.6 0.3 9.6e-56 188.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN91058.1 - 1.3e-24 85.9 0.0 2.4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DAO PF01266.19 KZN91060.1 - 1.8e-46 158.6 0.1 2.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN91060.1 - 0.002 18.0 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN91060.1 - 0.006 15.5 0.1 0.0091 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN91060.1 - 0.0093 15.9 0.3 0.02 14.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN91060.1 - 0.011 15.7 0.1 0.035 14.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KZN91060.1 - 0.017 15.1 0.3 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 KZN91060.1 - 0.046 13.4 2.2 0.15 11.8 0.2 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KZN91060.1 - 0.074 11.9 0.3 5.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN91060.1 - 0.089 11.4 0.2 0.45 9.0 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 KZN91060.1 - 0.12 11.8 0.4 0.21 11.0 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.17 KZN91063.1 - 1.7e-138 461.8 0.0 2e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN91063.1 - 4.4e-06 25.6 0.0 6.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) UDPGT PF00201.13 KZN91064.1 - 0.054 12.0 2.3 1.9 6.9 0.3 2.3 1 1 1 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Fungal_trans PF04082.13 KZN91065.1 - 8.8e-14 50.9 0.7 1.7e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91065.1 - 1.4e-08 34.4 4.9 4.6e-08 32.8 3.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KZN91065.1 - 1.2e-05 25.3 9.9 0.015 15.6 1.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN91065.1 - 0.0011 19.1 16.3 0.0025 18.0 1.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KZN91065.1 - 0.11 12.7 2.9 1.5 9.1 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KZN91065.1 - 0.15 12.3 0.3 0.15 12.3 0.2 3.7 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KZN91065.1 - 0.17 12.0 6.8 0.13 12.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FA_hydroxylase PF04116.8 KZN91066.1 - 2.4e-12 47.2 17.1 3.5e-12 46.7 10.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RTC PF01137.16 KZN91068.1 - 2.5e-36 124.5 0.0 4.4e-36 123.7 0.0 1.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase CPSase_L_D2 PF02786.12 KZN91070.1 - 5.5e-57 192.4 0.0 8.7e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KZN91070.1 - 6.8e-32 109.6 0.0 1.3e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KZN91070.1 - 1e-26 93.2 0.0 1.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KZN91070.1 - 6.5e-18 65.1 0.1 1.5e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Exo_endo_phos PF03372.18 KZN91070.1 - 3.7e-15 56.5 0.9 6.3e-15 55.7 0.6 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATPgrasp_Ter PF15632.1 KZN91070.1 - 1.1e-11 44.1 0.0 1.6e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KZN91070.1 - 7.2e-11 41.5 0.2 1.7e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KZN91070.1 - 1.3e-09 37.7 0.0 2.8e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KZN91070.1 - 3.5e-05 23.2 0.1 6.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KZN91070.1 - 0.0002 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 KZN91070.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RimK PF08443.6 KZN91070.1 - 0.0036 16.7 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KZN91070.1 - 0.0074 15.9 0.1 0.022 14.4 0.0 1.8 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_5 PF13549.1 KZN91070.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain HlyD PF00529.15 KZN91070.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 KZN91070.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Carboxyl_trans PF01039.17 KZN91071.1 - 1.6e-78 264.2 0.0 2.1e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF2422 PF10337.4 KZN91072.1 - 1.2e-116 390.2 7.6 6.1e-116 387.9 0.5 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KZN91072.1 - 2.1e-62 210.7 0.2 1.3e-61 208.1 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) HPP PF04982.8 KZN91072.1 - 2.6e-40 137.0 7.1 2.6e-40 137.0 4.9 3.8 4 0 0 4 4 4 1 HPP family FUSC_2 PF13515.1 KZN91072.1 - 1.5e-09 37.8 15.7 1.5e-09 37.8 10.9 4.7 4 1 1 5 5 5 1 Fusaric acid resistance protein-like Tmemb_14 PF03647.8 KZN91072.1 - 0.19 12.1 21.5 0.021 15.2 3.7 4.0 3 2 0 3 3 3 0 Transmembrane proteins 14C APH PF01636.18 KZN91074.1 - 3.5e-11 43.2 0.0 5.7e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KZN91074.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase AA_permease PF00324.16 KZN91075.1 - 1.4e-110 369.9 42.5 1.6e-110 369.7 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN91075.1 - 5.3e-40 137.2 49.4 6.4e-40 136.9 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease S-methyl_trans PF02574.11 KZN91076.1 - 2.4e-25 89.4 0.0 3.4e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase CAP59_mtransfer PF11735.3 KZN91077.1 - 2.5e-88 295.3 0.0 3.4e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1772 PF08592.6 KZN91079.1 - 0.0011 18.7 0.4 0.056 13.1 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) adh_short_C2 PF13561.1 KZN91080.1 - 2.1e-21 76.7 0.0 7.1e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN91080.1 - 3.8e-19 69.2 0.4 7.2e-19 68.3 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN91080.1 - 1.5e-06 28.0 0.3 5e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN91080.1 - 0.0031 16.9 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF4056 PF13265.1 KZN91080.1 - 0.05 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Polysacc_synt_2 PF02719.10 KZN91080.1 - 0.058 12.2 0.1 0.079 11.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein IncA PF04156.9 KZN91081.1 - 0.085 12.4 5.3 0.17 11.4 3.7 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KZN91081.1 - 1.4 6.6 2.8 2 6.1 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.13 KZN91084.1 - 1e-47 162.3 0.0 1.7e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 KZN91084.1 - 0.0075 16.0 0.2 0.035 13.9 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain GRAM PF02893.15 KZN91084.1 - 0.0099 15.3 0.0 0.024 14.1 0.0 1.7 1 1 0 1 1 1 1 GRAM domain CNH PF00780.17 KZN91085.1 - 4.3e-70 236.2 0.0 7.3e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KZN91085.1 - 1.8e-33 115.9 1.3 2.4e-33 115.5 0.3 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 KZN91085.1 - 3.4e-14 52.9 0.0 1e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Fungal_trans PF04082.13 KZN91086.1 - 6.1e-08 31.8 0.3 1.1e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_2 PF13532.1 KZN91087.1 - 1.5e-30 106.5 0.0 2.7e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SHOCT PF09851.4 KZN91087.1 - 0.00016 21.0 1.1 0.00034 19.9 0.8 1.6 1 0 0 1 1 1 1 Short C-terminal domain AMP-binding PF00501.23 KZN91088.1 - 3.1e-76 256.4 0.0 3.8e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN91088.1 - 7.4e-15 55.6 0.3 2.8e-14 53.8 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 KZN91089.1 - 9.1e-29 98.2 4.1 3.5e-05 23.4 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KZN91089.1 - 0.047 13.1 0.0 7.5 6.1 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B12 PF08122.7 KZN91090.1 - 2.1e-20 72.2 1.6 3.3e-20 71.5 1.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF2933 PF11666.3 KZN91090.1 - 0.27 10.7 5.0 0.39 10.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) CAF1 PF04857.15 KZN91091.1 - 4.4e-64 216.3 0.0 6.2e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 KZN91092.1 - 3.3e-168 559.7 0.0 4e-168 559.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KZN91092.1 - 1.8e-22 79.2 0.8 3.2e-21 75.2 0.1 2.4 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KZN91092.1 - 5.2e-15 55.2 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_11 PF13414.1 KZN91093.1 - 1.2e-13 50.4 7.1 9.8e-08 31.5 0.6 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KZN91093.1 - 4.1e-10 38.7 7.8 6.5e-05 22.5 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KZN91093.1 - 1e-09 37.6 5.1 0.0014 18.1 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KZN91093.1 - 1.3e-08 34.6 3.7 2.2e-06 27.4 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN91093.1 - 9.6e-06 25.0 1.8 0.0036 16.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN91093.1 - 1.4e-05 24.5 2.9 0.29 11.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KZN91093.1 - 4.5e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KZN91093.1 - 0.00012 22.3 0.5 0.007 16.6 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN91093.1 - 0.00015 22.3 7.6 0.01 16.4 0.6 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN91093.1 - 0.0012 18.6 0.4 0.85 9.5 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 KZN91093.1 - 0.0016 17.6 0.4 0.0025 17.0 0.3 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP SPO22 PF08631.5 KZN91093.1 - 0.011 14.8 0.2 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.7 KZN91093.1 - 0.02 14.6 0.8 0.57 10.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 KZN91093.1 - 0.043 13.6 1.5 0.5 10.2 0.2 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 KZN91093.1 - 0.044 14.2 3.6 0.25 11.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN91093.1 - 0.11 13.2 7.9 0.4 11.4 0.0 3.9 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN91093.1 - 0.36 10.8 0.0 0.36 10.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MARVEL PF01284.18 KZN91094.1 - 3.3e-08 33.4 2.8 5.7e-08 32.6 1.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain Methyltransf_3 PF01596.12 KZN91095.1 - 6.7e-18 64.4 0.0 5.6e-17 61.4 0.0 1.9 1 1 0 2 2 2 1 O-methyltransferase Methyltransf_24 PF13578.1 KZN91095.1 - 1e-11 45.5 0.0 2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KZN91095.1 - 0.0041 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 KZN91095.1 - 0.026 14.5 0.1 0.07 13.1 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91095.1 - 0.026 15.0 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2119 PF09892.4 KZN91095.1 - 0.033 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) GFO_IDH_MocA PF01408.17 KZN91096.1 - 9.9e-27 93.8 0.1 1.8e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN91096.1 - 3.2e-13 49.4 0.0 5.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KZN91096.1 - 0.00015 22.1 0.1 0.00032 21.0 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 KZN91096.1 - 0.0003 20.6 0.1 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KZN91096.1 - 0.017 15.3 0.0 0.057 13.7 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HPP PF04982.8 KZN91098.1 - 1.1e-34 118.8 7.6 1.1e-34 118.8 5.3 1.5 2 0 0 2 2 2 1 HPP family Bax1-I PF01027.15 KZN91098.1 - 4.6 6.7 14.0 0.44 10.1 1.4 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 ABC_tran PF00005.22 KZN91099.1 - 7.7e-45 152.5 0.0 9.4e-22 77.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KZN91099.1 - 3.2e-20 71.7 1.5 3.2e-20 71.7 1.0 2.7 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 KZN91099.1 - 3.4e-20 73.1 0.2 0.00016 21.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KZN91099.1 - 3.1e-10 39.6 0.3 0.19 10.9 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KZN91099.1 - 1e-08 35.7 2.3 0.04 14.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN91099.1 - 2.5e-08 33.2 0.2 0.001 18.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KZN91099.1 - 2.9e-06 28.1 0.0 0.037 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN91099.1 - 3.2e-06 27.2 0.0 0.094 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KZN91099.1 - 6.7e-06 25.3 0.9 0.0028 16.8 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KZN91099.1 - 8.9e-06 26.0 0.0 0.11 12.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KZN91099.1 - 1e-05 25.7 0.0 0.2 11.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KZN91099.1 - 1.7e-05 25.0 0.1 0.32 11.2 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KZN91099.1 - 2.2e-05 24.4 0.0 0.017 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KZN91099.1 - 3.5e-05 24.2 0.0 0.098 13.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_5 PF07728.9 KZN91099.1 - 8.9e-05 22.2 0.1 0.37 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KZN91099.1 - 0.00011 22.3 0.9 1.9 8.7 0.0 3.8 4 0 0 4 4 4 2 RNA helicase MMR_HSR1 PF01926.18 KZN91099.1 - 0.00015 21.7 0.1 0.14 12.1 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.7 KZN91099.1 - 0.00015 21.4 0.1 0.67 9.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 KZN91099.1 - 0.00032 19.8 0.2 0.081 11.9 0.0 3.1 5 0 0 5 5 4 1 AAA ATPase domain AAA_33 PF13671.1 KZN91099.1 - 0.0006 19.7 0.1 0.17 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KZN91099.1 - 0.00076 18.9 0.0 0.85 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KZN91099.1 - 0.0011 18.4 1.1 0.68 9.3 0.2 3.2 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 KZN91099.1 - 0.0016 18.3 0.3 0.32 10.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 KZN91099.1 - 0.0017 18.0 0.0 2.3 7.8 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KZN91099.1 - 0.0019 17.1 0.0 1.8 7.3 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain MobB PF03205.9 KZN91099.1 - 0.0027 17.4 0.2 0.055 13.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KZN91099.1 - 0.0029 17.5 0.0 2.8 7.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KZN91099.1 - 0.0029 17.1 0.0 0.04 13.4 0.0 2.5 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 KZN91099.1 - 0.021 13.8 0.7 6.2 5.6 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 VirE PF05272.6 KZN91099.1 - 0.075 12.4 0.2 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E NTPase_1 PF03266.10 KZN91099.1 - 0.078 12.6 0.2 7 6.3 0.1 2.5 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 KZN91099.1 - 0.094 12.5 2.8 12 5.6 0.0 3.7 2 1 1 3 3 3 0 Dynamin family DUF2813 PF11398.3 KZN91099.1 - 0.22 10.5 1.7 13 4.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DUF87 PF01935.12 KZN91099.1 - 0.28 10.9 2.8 19 4.9 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_24 PF13479.1 KZN91099.1 - 2.5 7.6 4.9 9.2 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF3584 PF12128.3 KZN91099.1 - 4.2 4.5 8.2 0.21 8.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) UQ_con PF00179.21 KZN91101.1 - 3e-42 143.3 0.1 1.8e-41 140.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KZN91101.1 - 9.3e-06 25.1 0.0 2.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Cyclin_N PF00134.18 KZN91101.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Prok-E2_B PF14461.1 KZN91101.1 - 0.00031 20.5 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.24 KZN91102.1 - 2.6e-40 137.6 0.0 4.8e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN91102.1 - 7.2e-07 29.4 0.2 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KZN91102.1 - 1.4e-05 25.0 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KZN91102.1 - 1.9e-05 23.7 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KZN91102.1 - 2.7e-05 23.9 0.0 7.8e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN91102.1 - 0.00027 20.9 0.1 0.0012 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KZN91102.1 - 0.00074 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KZN91102.1 - 0.0013 18.6 0.1 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KZN91102.1 - 0.0046 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN91102.1 - 0.0058 17.4 0.8 0.013 16.2 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KZN91102.1 - 0.0067 16.1 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KZN91102.1 - 0.007 15.8 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KZN91102.1 - 0.0089 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 KZN91102.1 - 0.011 15.0 0.6 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 KZN91102.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN91102.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KZN91102.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KZN91102.1 - 0.019 13.6 0.0 0.043 12.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 KZN91102.1 - 0.027 14.1 0.1 0.34 10.5 0.0 2.2 1 1 0 2 2 2 0 NACHT domain KaiC PF06745.8 KZN91102.1 - 0.032 13.3 0.2 0.42 9.6 0.0 2.2 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 KZN91102.1 - 0.039 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KZN91102.1 - 0.04 14.0 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KZN91102.1 - 0.049 13.1 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KZN91102.1 - 0.049 13.0 1.6 0.25 10.7 0.3 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KZN91102.1 - 0.054 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KZN91102.1 - 0.14 11.5 0.1 0.81 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 KZN91102.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 KZN91103.1 - 1.1e-19 69.5 21.1 6.3e-09 35.3 0.8 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat PBP1_TM PF14812.1 KZN91103.1 - 0.14 12.4 7.0 0.5 10.7 4.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 KZN91103.1 - 0.16 11.0 7.8 0.35 9.9 5.3 1.6 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KZN91103.1 - 1 9.6 8.3 2.1 8.6 5.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KZN91103.1 - 3.7 6.7 5.3 5.7 6.1 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein Mg_trans_NIPA PF05653.9 KZN91104.1 - 6.7e-62 209.1 5.6 7.3e-58 195.8 3.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KZN91104.1 - 2.4e-05 24.5 0.1 2.4e-05 24.5 0.1 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KZN91104.1 - 0.0001 22.3 0.6 0.0001 22.3 0.4 3.5 3 1 0 3 3 3 1 EamA-like transporter family DUF1211 PF06736.6 KZN91104.1 - 2.8 8.1 5.8 25 5.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Glyco_hydro_3 PF00933.16 KZN91105.1 - 3.8e-71 239.4 0.0 5.2e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN91105.1 - 2.9e-60 203.6 1.9 1.7e-59 201.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN91105.1 - 5e-22 77.6 0.3 5e-22 77.6 0.2 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KZN91105.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1034 PF06280.7 KZN91105.1 - 0.037 14.4 0.7 0.083 13.2 0.5 1.5 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) MAD PF05557.8 KZN91106.1 - 0.0029 15.7 0.9 0.0029 15.7 0.6 2.0 2 0 0 2 2 2 1 Mitotic checkpoint protein Med30 PF11315.3 KZN91106.1 - 0.028 14.5 0.4 7.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 DivIC PF04977.10 KZN91106.1 - 0.039 13.4 3.6 0.44 10.0 2.2 2.4 2 0 0 2 2 2 0 Septum formation initiator CENP-Q PF13094.1 KZN91106.1 - 0.057 13.4 0.1 0.057 13.4 0.1 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3837 PF12939.2 KZN91106.1 - 0.11 12.5 0.4 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF972 PF06156.8 KZN91106.1 - 0.63 10.4 4.4 2.9 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rootletin PF15035.1 KZN91106.1 - 2 8.3 11.9 31 4.4 8.0 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIVA PF05103.8 KZN91106.1 - 2.9 7.9 8.7 0.81 9.7 1.1 2.8 3 0 0 3 3 3 0 DivIVA protein DUF812 PF05667.6 KZN91106.1 - 3.1 6.1 9.0 0.14 10.6 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Striatin PF08232.7 KZN91106.1 - 6.3 7.1 11.8 16 5.8 2.8 3.3 2 1 1 3 3 3 0 Striatin family GRAM PF02893.15 KZN91107.1 - 8.3e-17 60.4 0.0 1.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain FAD_binding_4 PF01565.18 KZN91108.1 - 4.2e-28 97.5 0.7 6.8e-28 96.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN91108.1 - 2.2e-09 37.0 0.0 5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3309 PF11752.3 KZN91108.1 - 0.056 13.2 1.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Trypan_PARP PF05887.6 KZN91109.1 - 2.9 7.6 33.6 0.97 9.2 7.5 2.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4551 PF15087.1 KZN91109.1 - 8.7 4.5 20.5 12 4.1 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) UBN2_3 PF14244.1 KZN91110.1 - 0.0022 17.5 0.1 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sugar_tr PF00083.19 KZN91111.1 - 1.7e-64 218.0 26.4 1.9e-64 217.8 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91111.1 - 1.1e-14 53.9 25.9 1.1e-14 53.9 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_P21 PF05313.7 KZN91111.1 - 0.014 14.6 2.2 0.025 13.8 1.6 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Thioredoxin PF00085.15 KZN91112.1 - 5.4e-29 99.9 0.1 6.7e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KZN91112.1 - 8.7e-10 38.7 0.2 5.9e-09 36.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KZN91112.1 - 1.4e-09 37.9 0.1 7.2e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KZN91112.1 - 3.9e-07 29.7 0.4 9.9e-05 21.9 0.1 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KZN91112.1 - 5.1e-06 26.1 0.0 7.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KZN91112.1 - 0.00014 21.4 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 KZN91112.1 - 0.00031 20.7 0.3 0.44 10.5 0.0 2.5 1 1 2 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.1 KZN91112.1 - 0.00066 19.6 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 KZN91112.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 KZN91112.1 - 0.0027 17.2 0.1 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein DSBA PF01323.15 KZN91112.1 - 0.0063 16.0 1.2 1.4 8.3 0.1 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.1 KZN91112.1 - 0.0089 15.6 0.1 0.059 12.9 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Glutaredoxin PF00462.19 KZN91112.1 - 0.025 14.5 0.1 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 KZN91112.1 - 0.053 13.4 0.1 0.08 12.8 0.1 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.11 KZN91112.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosducin SIMPL PF04402.9 KZN91113.1 - 9.8e-28 97.4 3.7 2e-27 96.4 2.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF541) Dot_icm_IcmQ PF09475.5 KZN91113.1 - 0.098 11.8 0.0 9.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) HMA PF00403.21 KZN91115.1 - 1.7e-09 37.6 0.5 2.2e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain ABC2_membrane PF01061.19 KZN91116.1 - 2.2e-85 285.1 57.1 8.8e-46 155.7 10.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN91116.1 - 1.5e-36 125.6 0.1 1.7e-17 64.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KZN91116.1 - 3.9e-28 97.1 0.6 3.2e-23 81.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KZN91116.1 - 4.2e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KZN91116.1 - 5.4e-06 26.3 0.1 0.0051 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KZN91116.1 - 1.1e-05 24.9 0.2 0.0034 16.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 KZN91116.1 - 1.3e-05 24.4 48.6 0.00079 18.5 13.7 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 KZN91116.1 - 2.7e-05 24.9 0.0 0.041 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN91116.1 - 7.1e-05 22.2 0.2 0.0035 16.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN91116.1 - 0.00019 21.5 0.0 0.15 12.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KZN91116.1 - 0.00036 20.2 0.8 0.69 9.7 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 KZN91116.1 - 0.00047 20.4 0.1 0.084 13.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KZN91116.1 - 0.00054 19.4 1.7 0.011 15.2 0.5 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KZN91116.1 - 0.00062 18.9 0.0 0.0019 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KZN91116.1 - 0.0016 18.4 0.1 0.081 12.8 0.0 3.4 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KZN91116.1 - 0.002 18.1 0.5 0.13 12.2 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KZN91116.1 - 0.0023 17.9 0.4 0.025 14.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KZN91116.1 - 0.0052 16.4 1.1 1 9.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KZN91116.1 - 0.016 14.8 0.5 5.6 6.6 0.2 2.4 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 KZN91116.1 - 0.029 13.8 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KZN91116.1 - 0.033 13.8 0.0 5.2 6.6 0.0 3.0 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KZN91116.1 - 0.034 13.6 0.4 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 KZN91116.1 - 0.044 13.0 0.0 0.64 9.2 0.0 2.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KZN91116.1 - 0.13 12.5 0.0 20 5.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KZN91116.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 1 0 3 3 2 0 AAA domain DUF4246 PF14033.1 KZN91117.1 - 1.9e-168 561.1 0.0 2.3e-168 560.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Thioredoxin PF00085.15 KZN91118.1 - 3.3e-24 84.5 0.0 4.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 KZN91118.1 - 0.00017 21.4 0.0 0.019 14.8 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KZN91118.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KZN91118.1 - 0.0023 17.8 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KZN91118.1 - 0.0054 16.4 0.0 0.0063 16.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KZN91118.1 - 0.044 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Fungal_trans PF04082.13 KZN91120.1 - 5.2e-13 48.4 6.6 9.2e-13 47.6 4.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.12 KZN91121.1 - 6.6e-98 327.2 0.0 9.7e-98 326.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KZN91121.1 - 2e-52 177.1 0.7 3.8e-52 176.2 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 KZN91121.1 - 3e-52 177.3 0.0 7.3e-52 176.0 0.0 1.6 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 KZN91121.1 - 3.6e-12 46.6 0.4 1e-11 45.2 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Sugar_tr PF00083.19 KZN91122.1 - 1.3e-84 284.4 34.0 1.5e-84 284.2 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91122.1 - 8.9e-08 31.2 40.7 3.8e-07 29.1 28.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KZN91123.1 - 3.7e-33 114.7 25.9 6.3e-33 113.9 17.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 KZN91125.1 - 0.0073 14.7 0.0 0.016 13.6 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.22 KZN91126.1 - 1.6e-53 178.3 11.1 1.2e-18 66.5 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KZN91127.1 - 1.5e-29 102.6 0.3 2.9e-29 101.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PrpF PF04303.8 KZN91128.1 - 2.3e-78 263.5 2.7 5e-77 259.1 1.9 2.0 1 1 0 1 1 1 1 PrpF protein DUF4397 PF14344.1 KZN91128.1 - 0.046 14.0 0.2 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) 2OG-Fe_Oxy_2 PF10014.4 KZN91128.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe dioxygenase MFS_1 PF07690.11 KZN91129.1 - 4.7e-35 120.9 15.2 5.9e-35 120.6 10.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91129.1 - 7.7e-09 34.6 6.2 1e-08 34.2 4.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Sensor PF13796.1 KZN91129.1 - 0.0022 17.6 1.9 0.0029 17.2 0.0 2.2 2 1 0 2 2 2 1 Putative sensor DUF1772 PF08592.6 KZN91129.1 - 0.89 9.2 5.5 0.11 12.1 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Ribosomal_L19 PF01245.15 KZN91130.1 - 5.7e-18 64.7 1.1 9.2e-18 64.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Parathyroid PF01279.12 KZN91131.1 - 0.071 13.7 0.7 9 6.9 0.1 2.3 2 0 0 2 2 2 0 Parathyroid hormone family AMP-binding PF00501.23 KZN91132.1 - 5.3e-14 51.4 0.1 2.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 KZN91133.1 - 1e-35 122.7 0.1 2.4e-34 118.2 0.1 2.1 1 1 0 1 1 1 1 Nuclear pore complex component Hid1 PF12722.2 KZN91134.1 - 6.2e-282 937.4 0.0 9.8e-282 936.8 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KZN91134.1 - 2.6e-78 263.8 0.0 4.4e-78 263.0 0.0 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein GHL1-3 PF11308.3 KZN91134.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 KAT11 PF08214.6 KZN91137.1 - 4.2e-103 345.0 0.0 6.1e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.1 KZN91138.1 - 8.3e-12 44.7 0.2 5.1e-05 22.6 0.0 3.5 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KZN91138.1 - 9.9e-10 38.5 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KZN91138.1 - 0.0014 18.3 0.0 0.0044 16.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 FA_desaturase PF00487.19 KZN91138.1 - 0.52 9.7 6.7 0.071 12.5 1.0 2.0 2 0 0 2 2 2 0 Fatty acid desaturase Ank_2 PF12796.2 KZN91139.1 - 4.7e-15 55.6 2.2 7.6e-15 55.0 1.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN91139.1 - 3.5e-14 51.8 1.0 4.5e-11 41.9 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KZN91139.1 - 7.8e-14 51.3 2.7 4.2e-10 39.5 0.5 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN91139.1 - 2.3e-10 39.6 0.3 1.7e-07 30.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KZN91139.1 - 4.2e-09 36.6 0.4 2.6e-08 34.1 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) WW PF00397.21 KZN91140.1 - 1.4e-09 37.5 2.3 3.4e-09 36.3 1.6 1.6 1 0 0 1 1 1 1 WW domain Sfi1_C PF10638.4 KZN91140.1 - 0.048 14.0 0.6 0.048 14.0 0.4 1.6 2 0 0 2 2 2 0 Spindle body associated protein C-terminus CFEM PF05730.6 KZN91141.1 - 0.00011 21.8 5.1 0.00011 21.8 3.6 3.0 4 0 0 4 4 4 1 CFEM domain PNRC PF15365.1 KZN91141.1 - 2.7 8.0 10.8 1.5 8.9 2.4 3.5 3 1 0 3 3 3 0 Proline-rich nuclear receptor coactivator Hydrophobin PF01185.13 KZN91142.1 - 6.3e-15 55.3 7.4 8.6e-15 54.9 5.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin LETM1 PF07766.8 KZN91143.1 - 0.19 10.7 0.7 2 7.4 0.0 2.2 2 1 0 2 2 2 0 LETM1-like protein Cut8_N PF14482.1 KZN91143.1 - 0.39 10.7 5.7 13 5.8 2.3 2.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain NMO PF03060.10 KZN91144.1 - 7e-62 209.4 0.8 1.2e-61 208.6 0.6 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KZN91144.1 - 7.1e-11 41.5 0.0 0.0001 21.3 0.2 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KZN91144.1 - 4.3e-05 22.5 0.3 7.6e-05 21.7 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KZN91144.1 - 0.011 14.9 0.2 0.11 11.7 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KZN91144.1 - 0.018 13.9 0.1 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 KZN91144.1 - 0.034 13.0 0.4 0.074 11.9 0.3 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.6 KZN91144.1 - 0.06 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Sdh_cyt PF01127.17 KZN91145.1 - 7.8e-25 87.0 4.6 7.8e-25 87.0 3.2 1.3 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_3 PF13706.1 KZN91145.1 - 0.056 12.8 0.2 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Ribonucleas_3_3 PF14622.1 KZN91146.1 - 6.1e-28 97.3 0.0 1.3e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KZN91146.1 - 6.8e-05 23.2 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.16 KZN91147.1 - 5e-90 301.1 0.0 6.7e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KZN91147.1 - 8.3e-09 35.2 0.2 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KZN91147.1 - 0.077 12.1 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Gtr1_RagA PF04670.7 KZN91148.1 - 2.7e-94 314.6 0.3 3.3e-94 314.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KZN91148.1 - 1.6e-08 33.9 0.0 2.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KZN91148.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN91148.1 - 5.5e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN91148.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN91148.1 - 0.00034 20.0 0.0 0.00087 18.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KZN91148.1 - 0.003 17.0 0.3 0.0089 15.5 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KZN91148.1 - 0.009 14.9 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KZN91148.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KZN91148.1 - 0.098 11.8 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KZN91148.1 - 0.15 10.7 2.5 2.7 6.5 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 KZN91148.1 - 0.17 11.2 0.4 0.32 10.3 0.3 1.6 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 KZN91148.1 - 0.26 10.3 1.4 0.38 9.8 0.3 1.9 2 1 0 2 2 2 0 AIG1 family DUF1688 PF07958.6 KZN91149.1 - 8e-183 607.7 0.0 9.2e-183 607.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) NapE PF06796.6 KZN91150.1 - 0.043 13.1 0.2 0.098 11.9 0.1 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE TPR_11 PF13414.1 KZN91151.1 - 5.5e-07 29.1 0.0 8.6e-06 25.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 KZN91151.1 - 0.00018 21.2 0.0 0.00057 19.6 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.1 KZN91151.1 - 0.00018 22.0 0.3 0.059 14.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN91151.1 - 0.00021 20.9 0.3 0.47 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN91151.1 - 0.0035 16.9 0.1 7.3 6.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN91151.1 - 0.0099 15.8 1.5 0.062 13.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 KZN91151.1 - 0.076 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain GCD14 PF08704.5 KZN91152.1 - 8.1e-60 202.3 0.2 3.5e-59 200.2 0.0 2.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KZN91152.1 - 0.00042 20.3 0.0 0.00083 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91152.1 - 0.063 13.8 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase PF05221.12 KZN91152.1 - 0.084 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase tRNA-synt_1e PF01406.14 KZN91153.1 - 1.2e-114 382.4 0.0 2.2e-114 381.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KZN91153.1 - 1.6e-06 27.0 0.6 0.027 13.1 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KZN91153.1 - 0.048 13.9 0.1 0.048 13.9 0.0 2.3 2 0 0 2 2 2 0 DALR domain Herpes_pp85 PF04637.7 KZN91153.1 - 0.055 11.7 0.1 0.093 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Transaldolase PF00923.14 KZN91154.1 - 2.1e-47 161.6 0.1 2.8e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Transaldolase PQ-loop PF04193.9 KZN91155.1 - 1.5e-40 136.5 12.0 7.9e-21 73.3 1.5 2.6 2 0 0 2 2 2 2 PQ loop repeat SGS PF05002.10 KZN91157.1 - 3e-27 94.1 2.7 1.2e-26 92.2 1.9 2.1 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KZN91157.1 - 2.1e-17 63.4 0.1 3.6e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KZN91157.1 - 2.1e-09 36.8 4.7 4.7e-09 35.7 2.1 2.1 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KZN91157.1 - 0.00051 19.5 3.4 0.18 11.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN91157.1 - 0.0019 17.9 7.1 0.74 9.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN91157.1 - 0.011 16.4 5.6 0.28 11.9 0.9 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN91157.1 - 0.027 14.2 1.2 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4129 PF13559.1 KZN91157.1 - 0.082 12.8 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) TPR_12 PF13424.1 KZN91157.1 - 0.14 12.1 5.3 1.3 9.0 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Prenyltrans PF00432.16 KZN91158.1 - 1.5e-33 113.9 8.9 1.4e-10 40.5 0.3 4.5 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KZN91158.1 - 2.7e-26 91.6 0.0 2.8e-16 59.4 0.2 5.3 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KZN91158.1 - 1.4e-25 89.9 0.6 7e-14 52.1 0.2 5.1 3 1 1 4 4 4 4 Prenyltransferase-like Pec_lyase PF09492.5 KZN91158.1 - 3.8e-07 29.5 2.9 1.8 7.6 0.0 4.9 3 1 1 5 5 5 4 Pectic acid lyase TP6A_N PF04406.9 KZN91159.1 - 6e-16 57.8 0.1 1.1e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase UQ_con PF00179.21 KZN91160.1 - 1.8e-50 169.9 0.0 2.1e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.10 KZN91161.1 - 1.2e-55 188.0 2.7 1e-29 103.1 0.1 3.0 1 1 0 2 2 2 2 Scramblase DUF2076 PF09849.4 KZN91162.1 - 0.016 15.2 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.14 KZN91163.1 - 1.3e-27 95.4 0.0 2e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein GMC_oxred_N PF00732.14 KZN91164.1 - 1.3e-52 178.8 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91164.1 - 2.1e-43 148.0 0.1 3.8e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN91164.1 - 9.6e-07 27.9 0.5 0.00041 19.3 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN91164.1 - 5.3e-06 25.5 0.1 1.8e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN91164.1 - 4.5e-05 23.3 0.4 0.00012 22.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN91164.1 - 0.00011 22.1 0.2 0.00027 20.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN91164.1 - 0.001 18.1 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN91164.1 - 0.0041 15.6 0.1 0.034 12.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KZN91164.1 - 0.014 14.4 0.1 0.029 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KZN91164.1 - 0.017 14.0 0.3 0.017 14.0 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN91164.1 - 0.092 11.3 0.2 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 KZN91164.1 - 0.1 12.2 0.5 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KZN91164.1 - 0.11 12.5 0.8 13 5.8 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN91164.1 - 0.14 11.1 0.5 0.28 10.2 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF500 PF04366.7 KZN91165.1 - 1.2e-39 134.5 0.5 2e-39 133.9 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) HGWP PF03578.10 KZN91166.1 - 0.058 12.7 0.3 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 HGWP repeat Rad9_Rad53_bind PF08605.5 KZN91168.1 - 1.1e-30 106.0 0.0 1.8e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 KZN91168.1 - 1.4e-08 34.7 0.0 2.9e-07 30.5 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain tRNA_int_endo PF01974.12 KZN91169.1 - 1.1e-20 73.2 0.4 2.7e-20 71.9 0.3 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KZN91169.1 - 9.3e-07 28.3 0.0 0.00054 19.4 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.7 KZN91170.1 - 1e-21 76.3 0.2 1.2e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 KZN91171.1 - 2e-30 104.4 4.6 3.9e-30 103.4 3.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 KZN91171.1 - 0.13 11.8 1.5 0.44 10.0 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 KZN91171.1 - 1.6 8.7 19.1 0.067 13.1 7.4 2.8 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator DUF3995 PF13160.1 KZN91172.1 - 3.3 7.7 13.2 0.15 12.1 1.9 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3995) Peptidase_M18 PF02127.10 KZN91173.1 - 9.4e-134 446.1 0.0 1.1e-133 445.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KZN91173.1 - 0.048 12.4 0.2 0.95 8.1 0.0 2.4 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase ADH_N PF08240.7 KZN91174.1 - 1.4e-27 95.6 1.8 1.4e-27 95.6 1.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KZN91174.1 - 1.7e-05 24.3 0.5 5.6e-05 22.7 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KZN91174.1 - 0.00027 20.4 0.3 0.2 11.2 0.0 2.9 2 1 0 2 2 2 2 Zinc-binding dehydrogenase Hap4_Hap_bind PF10297.4 KZN91175.1 - 5.1e-09 35.6 7.1 5.1e-09 35.6 4.9 2.5 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KZN91175.1 - 6.4e-08 32.4 8.0 3.3e-05 23.7 6.2 2.3 1 1 1 2 2 2 1 bZIP transcription factor Filament PF00038.16 KZN91175.1 - 0.0025 17.3 1.7 0.0039 16.7 1.2 1.3 1 0 0 1 1 1 1 Intermediate filament protein bZIP_Maf PF03131.12 KZN91175.1 - 0.025 14.8 2.5 0.08 13.2 1.8 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2408 PF10303.4 KZN91175.1 - 0.034 14.2 0.4 0.059 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin_1 PF12718.2 KZN91175.1 - 0.036 13.9 2.4 0.059 13.2 1.7 1.3 1 0 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.6 KZN91175.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 KZN91175.1 - 0.12 12.2 10.9 0.25 11.2 7.4 1.7 1 1 0 1 1 1 0 Basic region leucine zipper FUSC PF04632.7 KZN91175.1 - 0.27 9.5 1.6 0.41 9.0 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2051 PF09738.4 KZN91175.1 - 0.29 10.3 4.3 0.41 9.8 3.0 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) SRP54 PF00448.17 KZN91176.1 - 2.2e-75 252.3 3.2 4.1e-75 251.5 2.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KZN91176.1 - 8.5e-24 83.8 0.5 8.5e-24 83.8 0.4 4.2 4 1 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 KZN91176.1 - 4.1e-16 58.8 0.6 8.4e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KZN91176.1 - 7.9e-10 38.4 0.4 1.9e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KZN91176.1 - 5.6e-07 29.5 0.2 2.2e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KZN91176.1 - 3.1e-05 23.7 0.1 8.5e-05 22.2 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 KZN91176.1 - 3.2e-05 23.9 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN91176.1 - 3.3e-05 24.6 0.0 7.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KZN91176.1 - 6.5e-05 22.4 0.5 0.00021 20.7 0.3 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KZN91176.1 - 0.00031 19.9 0.1 0.0008 18.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin ArgK PF03308.11 KZN91176.1 - 0.00057 18.7 0.3 0.00057 18.7 0.2 2.5 2 1 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 KZN91176.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KZN91176.1 - 0.00062 19.7 0.1 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN91176.1 - 0.0027 17.8 0.1 0.0086 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain 6PF2K PF01591.13 KZN91176.1 - 0.0035 16.4 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase ATP_bind_1 PF03029.12 KZN91176.1 - 0.0041 16.6 0.6 0.014 14.9 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KZN91176.1 - 0.0042 16.3 1.4 1.3 8.1 0.7 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 KZN91176.1 - 0.0065 15.8 0.1 0.02 14.2 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KZN91176.1 - 0.0097 15.8 0.1 0.026 14.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN91176.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KZN91176.1 - 0.055 12.8 0.0 0.096 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 KZN91176.1 - 0.061 12.7 0.2 0.18 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 KZN91176.1 - 0.073 12.3 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family VirE PF05272.6 KZN91176.1 - 0.086 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.22 KZN91176.1 - 0.091 13.0 0.7 0.38 11.0 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Torsin PF06309.6 KZN91176.1 - 0.12 12.2 0.1 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Torsin Rrp15p PF07890.7 KZN91177.1 - 2.1e-33 115.1 5.2 4.7e-33 114.0 3.6 1.6 1 0 0 1 1 1 1 Rrp15p DUF1373 PF07117.6 KZN91177.1 - 0.092 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Fer2 PF00111.22 KZN91178.1 - 5.5e-14 51.6 1.0 7.7e-14 51.2 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 KZN91179.1 - 5.3e-13 48.4 0.3 0.053 13.2 0.0 5.4 4 1 0 4 4 4 4 Mitochondrial carrier protein PhoD PF09423.5 KZN91180.1 - 5.5e-57 193.3 0.0 7.6e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KZN91180.1 - 0.022 14.9 0.3 0.063 13.4 0.2 1.9 1 0 0 1 1 1 0 Fibronectin type III domain Glyco_hydro_18 PF00704.23 KZN91181.1 - 9.1e-10 38.5 0.0 2.7e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 KGG PF10685.4 KZN91182.1 - 3.2e-17 61.9 13.3 2.2e-10 40.1 1.9 3.2 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif DUF869 PF05911.6 KZN91183.1 - 9e-07 27.5 42.7 0.00043 18.6 22.7 2.2 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) Metal_resist PF13801.1 KZN91183.1 - 0.0023 17.9 6.5 0.0023 17.9 4.5 6.6 5 2 2 7 7 7 1 Heavy-metal resistance HOOK PF05622.7 KZN91183.1 - 1.4 6.6 59.9 0.055 11.2 20.7 4.1 3 1 1 4 4 4 0 HOOK protein Fungal_trans PF04082.13 KZN91185.1 - 4.3e-22 78.2 0.0 7.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KZN91186.1 - 5.3e-93 309.9 57.4 1.6e-48 164.6 17.3 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN91186.1 - 1.6e-38 132.1 0.1 1.5e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN91186.1 - 3.4e-37 126.2 6.1 7.7e-34 115.4 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KZN91186.1 - 2.7e-22 78.6 0.1 6.2e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KZN91186.1 - 1e-06 28.3 0.1 0.00044 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN91186.1 - 9.6e-06 24.8 0.3 0.0052 15.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN91186.1 - 5.4e-05 23.2 1.0 0.0089 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KZN91186.1 - 0.00017 20.7 43.2 0.032 13.2 13.4 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KZN91186.1 - 0.00045 19.6 3.0 0.02 14.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KZN91186.1 - 0.00073 19.0 0.9 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KZN91186.1 - 0.0012 18.6 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN91186.1 - 0.0018 18.5 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KZN91186.1 - 0.0022 18.1 0.9 0.53 10.4 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KZN91186.1 - 0.0032 16.7 0.0 0.38 9.9 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.6 KZN91186.1 - 0.0054 16.2 1.9 0.21 11.1 0.4 2.8 2 0 0 2 2 2 1 Plant PDR ABC transporter associated NACHT PF05729.7 KZN91186.1 - 0.0064 16.1 3.3 2.6 7.6 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 KZN91186.1 - 0.007 17.1 0.1 0.5 11.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 KZN91186.1 - 0.0087 16.0 0.0 2.1 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN91186.1 - 0.011 15.4 0.1 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KZN91186.1 - 0.011 15.8 0.4 1 9.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KZN91186.1 - 0.027 14.9 0.0 4 7.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KZN91186.1 - 0.04 13.3 0.1 3.1 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 KZN91186.1 - 0.18 11.7 0.7 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KZN91186.1 - 0.18 11.2 0.2 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KZN91186.1 - 0.19 11.3 0.2 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.8 KZN91187.1 - 6.6e-67 225.1 0.0 9.4e-67 224.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN91187.1 - 1e-11 44.5 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KZN91187.1 - 6.6e-09 35.0 0.5 1.3e-08 34.0 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KZN91187.1 - 8.3e-06 24.6 0.0 2e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KZN91187.1 - 1.3e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KZN91187.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 KZN91187.1 - 0.027 13.7 0.0 0.073 12.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Ribonuc_L-PSP PF01042.16 KZN91188.1 - 3.7e-39 133.2 0.0 4e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 KZN91188.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Sugar_tr PF00083.19 KZN91189.1 - 6.9e-85 285.2 20.4 7.9e-85 285.0 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91189.1 - 8.5e-12 44.4 20.2 8.5e-12 44.4 14.0 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2 PF04550.7 KZN91189.1 - 0.01 15.8 0.9 0.037 14.0 0.4 2.1 2 0 0 2 2 2 0 Phage holin family 2 UNC-93 PF05978.11 KZN91189.1 - 0.16 11.4 9.3 0.26 10.7 0.5 3.3 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 DUF1593 PF07632.6 KZN91190.1 - 4.9e-92 307.9 0.0 6.1e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) MFS_1 PF07690.11 KZN91191.1 - 2.3e-19 69.3 30.1 2.3e-19 69.3 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_2 PF02230.11 KZN91192.1 - 1.1e-22 80.5 0.0 8.4e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KZN91192.1 - 1.9e-05 24.4 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN91192.1 - 7.2e-05 22.7 0.1 0.00028 20.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KZN91192.1 - 0.00011 21.6 0.0 0.00022 20.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) APH PF01636.18 KZN91193.1 - 1e-05 25.4 0.2 0.017 14.8 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.23 KZN91194.1 - 1.8e-16 60.5 0.7 1.2e-15 57.8 0.0 2.2 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 CoA_transf_3 PF02515.12 KZN91195.1 - 1.3e-49 168.0 0.0 1.7e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III GMC_oxred_N PF00732.14 KZN91196.1 - 2.3e-58 197.7 0.0 3e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91196.1 - 5.5e-35 120.7 0.0 1.4e-34 119.4 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN91196.1 - 0.00027 20.8 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN91196.1 - 0.0028 16.5 0.1 0.042 12.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KZN91196.1 - 0.012 14.4 0.0 0.072 11.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN91196.1 - 0.047 13.5 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN91196.1 - 0.061 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein SeqA PF03925.8 KZN91196.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 SeqA protein HI0933_like PF03486.9 KZN91196.1 - 0.2 10.0 0.1 0.32 9.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Aminotran_3 PF00202.16 KZN91198.1 - 1.6e-90 303.4 0.0 1.9e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NmrA PF05368.8 KZN91199.1 - 5.6e-35 120.6 0.0 6.7e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KZN91199.1 - 2.2e-13 50.6 0.0 3.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN91199.1 - 3.5e-07 29.2 0.0 4.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN91199.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN91199.1 - 0.0037 16.2 0.0 0.0052 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KZN91199.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 KZN91201.1 - 5.2e-21 74.6 0.9 1.4e-20 73.2 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91201.1 - 1.4e-05 24.9 9.5 2.3e-05 24.2 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3294 PF07957.6 KZN91201.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MFS_1 PF07690.11 KZN91202.1 - 2.6e-12 46.1 23.9 2.6e-12 46.1 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN91202.1 - 1.9e-06 27.4 1.4 6.7e-06 25.6 1.0 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KZN91202.1 - 0.0025 16.4 10.3 0.0025 16.4 7.1 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter Transketolase_N PF00456.16 KZN91203.1 - 2.9e-17 62.5 0.7 4.1e-16 58.7 0.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KZN91203.1 - 4.5e-10 39.5 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KZN91203.1 - 4.8e-06 26.1 0.6 1.7e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 KZN91203.1 - 0.00013 21.5 0.9 0.00076 19.0 0.6 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KZN91203.1 - 0.00038 19.2 0.0 0.0006 18.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_30 PF02055.11 KZN91204.1 - 3.5e-44 150.8 2.2 4.5e-44 150.5 1.5 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Gly_transf_sug PF04488.10 KZN91205.1 - 6.3e-13 49.0 0.2 1.7e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Inhibitor_I48 PF10467.4 KZN91205.1 - 0.00016 21.6 0.5 0.0026 17.6 0.0 2.3 2 1 0 2 2 2 1 Peptidase inhibitor clitocypin TcdA_TcdB PF12919.2 KZN91205.1 - 0.0063 15.0 0.4 0.016 13.6 0.0 1.7 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 KZN91207.1 - 1.1e-34 119.7 33.6 1.1e-34 119.7 23.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_I_A49 PF06870.7 KZN91208.1 - 2.3e-49 168.0 0.0 9.3e-36 123.2 0.0 2.6 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.16 KZN91209.1 - 7.3e-87 291.6 0.0 9.2e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KZN91209.1 - 9.5e-07 27.4 0.0 1.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KZN91209.1 - 9.1e-06 24.6 0.0 1.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KZN91209.1 - 0.00064 18.8 0.2 0.0019 17.3 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KZN91209.1 - 0.005 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Usp PF00582.21 KZN91210.1 - 2.6e-19 69.7 1.1 1.4e-17 64.1 0.8 2.7 1 1 0 1 1 1 1 Universal stress protein family ATP-synt_ab PF00006.20 KZN91211.1 - 4.2e-62 209.4 0.0 5.5e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KZN91211.1 - 2.4e-16 60.1 0.0 4.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KZN91211.1 - 5.3e-11 42.5 0.2 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KZN91211.1 - 0.00099 18.9 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain Trp_syntA PF00290.15 KZN91212.1 - 5.4e-93 310.2 0.0 9.6e-93 309.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KZN91212.1 - 1.1e-46 159.4 0.7 1.8e-46 158.7 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 KZN91215.1 - 1.8e-25 88.9 0.3 2.8e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN91215.1 - 2.1e-11 44.8 0.1 5.8e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN91215.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KZN91215.1 - 0.062 13.3 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KZN91215.1 - 0.097 12.5 0.9 0.23 11.3 0.6 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF605 PF04652.11 KZN91216.1 - 4.1 6.7 17.0 5 6.4 11.8 1.2 1 0 0 1 1 1 0 Vta1 like GYF PF02213.11 KZN91217.1 - 1.2e-17 63.2 0.1 2.6e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 GYF domain MIP PF00230.15 KZN91220.1 - 6.7e-53 179.4 8.7 8.6e-53 179.1 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 KZN91221.1 - 9.4e-73 244.0 0.5 1.8e-72 243.1 0.4 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KZN91221.1 - 7.8e-66 221.8 0.0 1.3e-65 221.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KZN91221.1 - 0.024 13.9 0.5 6.1 6.0 0.0 3.0 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF2625 PF10946.3 KZN91221.1 - 0.084 11.8 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 p450 PF00067.17 KZN91222.1 - 1.3e-60 205.2 0.0 1.8e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_2 PF14608.1 KZN91223.1 - 3.7e-09 36.2 57.4 2.8e-05 23.9 7.9 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KZN91223.1 - 0.0015 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 KZN91224.1 - 4e-28 98.6 0.0 5.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN91224.1 - 2.2e-13 49.9 1.9 2.2e-12 46.8 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN91224.1 - 3.1e-06 26.3 0.1 4.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN91224.1 - 0.00017 20.8 0.2 0.0016 17.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN91224.1 - 0.013 13.9 0.0 0.25 9.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KZN91224.1 - 0.021 13.7 0.2 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KZN91224.1 - 0.03 14.7 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN91224.1 - 0.041 13.9 0.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN91224.1 - 0.051 12.4 0.1 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NOC3p PF07540.6 KZN91224.1 - 0.12 12.6 0.1 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Nucleolar complex-associated protein Mago-bind PF09282.5 KZN91225.1 - 4.5e-14 51.6 3.5 7.9e-14 50.9 2.4 1.4 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.7 KZN91226.1 - 3.8e-23 80.8 2.7 4.6e-23 80.5 1.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.1 KZN91226.1 - 0.011 15.2 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) zf-UBR PF02207.15 KZN91227.1 - 3.7e-17 61.8 14.9 9.3e-17 60.5 10.3 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 KZN91227.1 - 0.00014 21.6 1.7 0.00014 21.6 1.2 4.7 4 1 1 5 5 5 1 Ring finger domain ClpS PF02617.12 KZN91227.1 - 0.00044 19.9 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.1 KZN91227.1 - 0.0063 16.5 0.8 0.0063 16.5 0.5 4.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.7 KZN91227.1 - 0.25 9.1 6.0 0.5 8.2 4.2 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KZN91227.1 - 2.6 7.0 6.0 5.1 6.0 4.1 1.4 1 0 0 1 1 1 0 BUD22 RED_N PF07808.8 KZN91228.1 - 4e-08 32.7 0.5 8.1e-08 31.7 0.4 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.7 KZN91228.1 - 1.4 8.8 4.7 0.21 11.3 0.2 1.9 2 0 0 2 2 2 0 Gas vesicle protein G Fungal_trans_2 PF11951.3 KZN91229.1 - 0.48 8.9 10.7 1.5 7.3 3.1 2.8 1 1 0 2 2 2 0 Fungal specific transcription factor domain AKAP7_NLS PF10469.4 KZN91230.1 - 1e-16 61.3 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 KZN91231.1 - 2.5e-170 567.3 10.9 2.5e-170 567.3 7.5 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Ribosomal_L30 PF00327.15 KZN91232.1 - 1.1e-15 56.8 0.2 1.5e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 KZN91233.1 - 8.8e-23 80.3 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KZN91233.1 - 1.6e-08 33.7 0.0 1.1e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KZN91233.1 - 1.8e-06 27.1 0.0 3.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KZN91233.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KZN91233.1 - 0.099 10.9 0.0 0.67 8.1 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF1744 PF08490.7 KZN91233.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) HMGL-like PF00682.14 KZN91234.1 - 5.6e-70 235.6 0.7 9.2e-70 234.9 0.5 1.3 1 0 0 1 1 1 1 HMGL-like DUF939_C PF11728.3 KZN91235.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 DUF939 C-terminal domain NAD_binding_2 PF03446.10 KZN91236.1 - 2.3e-32 112.0 0.0 3.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN91236.1 - 5e-23 81.4 0.0 7.2e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KZN91236.1 - 2.6e-05 24.5 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 KZN91236.1 - 0.0015 17.3 0.0 0.0021 16.8 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_Gly3P_dh_N PF01210.18 KZN91236.1 - 0.0089 15.7 0.0 0.04 13.6 0.0 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding PF02629.14 KZN91236.1 - 0.073 13.5 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain PTH2 PF01981.11 KZN91237.1 - 1.9e-42 143.5 0.1 2.6e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.8 KZN91238.1 - 2.4e-177 591.0 59.8 2.7e-177 590.8 41.5 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.16 KZN91239.1 - 1.5e-92 310.3 0.0 1.8e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF155 PF02582.9 KZN91240.1 - 2.2e-57 193.7 0.0 3.7e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3753 PF12575.3 KZN91240.1 - 0.18 11.6 1.9 0.42 10.4 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Pox_A_type_inc PF04508.7 KZN91241.1 - 0.06 13.1 1.1 0.88 9.5 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PEP_mutase PF13714.1 KZN91242.1 - 1.2e-66 224.3 7.6 1.3e-66 224.2 5.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Hydrolase_6 PF13344.1 KZN91242.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ComA PF02679.10 KZN91242.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) HAD_2 PF13419.1 KZN91243.1 - 1.1e-10 41.9 0.0 2.7e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN91243.1 - 1.6e-07 30.9 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN91243.1 - 6.8e-07 29.9 0.0 4.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase APH PF01636.18 KZN91244.1 - 4.3e-17 62.6 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KZN91244.1 - 0.0021 17.0 0.0 0.03 13.2 0.0 2.0 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.6 KZN91244.1 - 0.11 11.1 0.1 0.72 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 KZN91244.1 - 0.18 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Vps54 PF07928.7 KZN91245.1 - 1.3e-40 138.6 0.1 4.1e-40 137.0 0.0 2.0 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KZN91245.1 - 6.7e-07 28.5 0.7 6.7e-07 28.5 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) zf-H2C2_2 PF13465.1 KZN91246.1 - 3.6e-20 71.1 30.4 2.9e-07 30.4 0.9 5.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 KZN91246.1 - 1.9e-19 68.7 27.3 2.5e-05 24.3 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN91246.1 - 7.7e-13 47.8 27.3 0.00046 20.3 3.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN91246.1 - 3.8e-05 23.6 8.4 0.23 11.6 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN91246.1 - 0.0012 18.9 16.0 0.012 15.7 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN91246.1 - 0.031 14.1 17.5 1.6 8.7 0.9 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 KZN91246.1 - 0.086 12.5 0.3 0.086 12.5 0.2 3.3 5 0 0 5 5 5 0 XPA protein N-terminal Yippee-Mis18 PF03226.9 KZN91246.1 - 0.41 10.7 2.7 7 6.7 0.2 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_1 PF00130.17 KZN91246.1 - 1.4 8.6 6.9 0.91 9.3 0.8 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.7 KZN91246.1 - 2 8.4 5.7 4.6 7.3 0.1 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DDE_Tnp_1_6 PF13751.1 KZN91246.1 - 2.2 8.2 7.7 0.24 11.4 2.1 1.7 2 0 0 2 2 2 0 Transposase DDE domain Zn-ribbon_8 PF09723.5 KZN91246.1 - 2.8 7.9 12.7 26 4.8 1.1 4.0 4 1 0 4 4 4 0 Zinc ribbon domain Fringe PF02434.11 KZN91247.1 - 9.5e-10 38.1 0.0 1.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 KZN91247.1 - 1.6e-06 27.5 0.1 1.2e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF604 SRP72 PF08492.7 KZN91248.1 - 7e-18 64.7 1.8 7e-18 64.7 1.3 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 KZN91248.1 - 5.9e-05 23.1 12.0 1.2 9.3 0.1 4.4 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KZN91248.1 - 6.4e-05 22.5 10.6 2.2 8.4 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN91248.1 - 6.8e-05 23.1 22.3 0.33 11.3 0.6 7.2 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN91248.1 - 0.0035 17.8 27.4 8.6 7.3 0.0 9.3 6 3 5 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN91248.1 - 0.0042 16.9 14.9 0.22 11.4 0.1 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KZN91248.1 - 0.02 14.9 8.6 2.2 8.4 0.6 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN91248.1 - 0.021 14.5 9.4 2.7 7.9 0.1 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 KZN91248.1 - 0.1 12.6 0.8 22 5.3 0.0 4.0 5 0 0 5 5 5 0 PPR repeat SPOB_a PF14689.1 KZN91248.1 - 0.12 11.9 1.6 0.42 10.2 0.2 2.6 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_6 PF13174.1 KZN91248.1 - 1.1 9.8 11.2 66 4.2 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN91248.1 - 3.9 7.2 11.8 2.8 7.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.17 KZN91249.1 - 1e-15 58.3 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KZN91249.1 - 0.0019 18.5 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KZN91249.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KZN91250.1 - 1.1e-38 132.9 32.6 4.9e-27 94.6 7.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KZN91250.1 - 8.7e-32 110.1 52.1 1.3e-22 79.9 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DiS_P_DiS PF06750.8 KZN91250.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain LRRC37AB_C PF14914.1 KZN91250.1 - 0.25 10.7 0.4 0.51 9.7 0.3 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain PhyH PF05721.8 KZN91251.1 - 1.3e-19 71.0 0.0 1.8e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KZN91251.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sec6 PF06046.8 KZN91252.1 - 0.06 11.4 0.0 0.078 11.0 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 RepB PF07506.6 KZN91252.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RepB plasmid partitioning protein vWA-TerF-like PF10138.4 KZN91253.1 - 8.7e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus E1-E2_ATPase PF00122.15 KZN91254.1 - 1.4e-21 76.5 0.0 5.2e-21 74.7 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN91254.1 - 3.4e-16 60.2 0.0 2.2e-15 57.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN91254.1 - 9.5e-15 55.2 0.1 7.7e-14 52.3 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN91254.1 - 6.8e-10 38.7 0.0 2.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN91254.1 - 0.0021 17.6 0.1 0.0063 16.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 KZN91254.1 - 0.035 13.5 5.5 0.28 10.6 0.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DUF4181 PF13789.1 KZN91254.1 - 0.058 13.3 0.1 0.058 13.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) RELT PF12606.3 KZN91254.1 - 7.6 5.7 6.0 24 4.1 4.1 1.8 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 MFS_1 PF07690.11 KZN91256.1 - 7e-30 103.9 59.8 3.4e-25 88.5 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91256.1 - 3.7e-15 55.4 30.4 4.4e-14 51.9 21.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_3 PF13302.1 KZN91257.1 - 3.4e-09 37.0 0.0 4.2e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN91257.1 - 0.0036 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Phytase PF02333.10 KZN91258.1 - 4.1e-63 213.3 0.3 1.8e-59 201.4 0.1 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.8 KZN91258.1 - 0.00015 21.8 12.7 0.00015 21.8 8.8 2.5 2 0 0 2 2 2 1 EGF-like domain PQQ_3 PF13570.1 KZN91258.1 - 0.093 13.0 1.2 7.7 6.9 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain Glyco_transf_8 PF01501.15 KZN91259.1 - 2.4e-06 27.0 1.0 6.2e-06 25.7 0.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KZN91259.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Aminotran_3 PF00202.16 KZN91260.1 - 2.6e-83 279.6 0.0 3.1e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KZN91260.1 - 8.5e-05 21.6 0.0 0.0006 18.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II TonB_2 PF13103.1 KZN91260.1 - 0.056 13.4 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 TonB C terminal Fungal_trans_2 PF11951.3 KZN91261.1 - 6.3e-31 107.3 0.0 7.7e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeobox PF00046.24 KZN91262.1 - 3.8e-19 68.0 2.3 7.2e-19 67.1 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KZN91262.1 - 0.0009 18.8 0.9 0.0019 17.8 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain SR-25 PF10500.4 KZN91262.1 - 0.027 13.9 2.1 0.052 13.0 1.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANF_receptor PF01094.23 KZN91262.1 - 0.058 12.1 0.3 0.12 11.0 0.2 1.5 1 1 0 1 1 1 0 Receptor family ligand binding region PGP_phosphatase PF09419.5 KZN91263.1 - 1.7e-60 203.1 0.0 2.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KZN91263.1 - 0.00042 19.9 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN91263.1 - 0.11 12.8 0.2 4.9 7.5 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LSM PF01423.17 KZN91264.1 - 7.1e-15 54.3 0.5 9.7e-15 53.8 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN91264.1 - 0.029 14.3 0.2 0.053 13.4 0.2 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Fungal_trans PF04082.13 KZN91265.1 - 3.2e-09 36.0 0.3 4.9e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.17 KZN91266.1 - 3.5e-19 69.2 0.1 6.9e-19 68.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MFS_1 PF07690.11 KZN91268.1 - 2.1e-29 102.3 47.9 2.1e-29 102.3 33.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91268.1 - 7.3e-07 28.1 18.8 7.3e-07 28.1 13.1 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter Adaptin_binding PF10199.4 KZN91269.1 - 7.1e-20 71.6 3.2 3.5e-19 69.4 2.7 1.8 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.8 KZN91269.1 - 0.019 14.5 0.4 0.019 14.5 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF607 PF04678.8 KZN91270.1 - 1e-44 152.5 0.2 2.8e-44 151.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Sporozoite_P67 PF05642.6 KZN91270.1 - 0.028 12.3 0.1 0.051 11.4 0.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen B12D PF06522.6 KZN91271.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Hpt PF01627.18 KZN91272.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Hpt domain NusB PF01029.13 KZN91272.1 - 0.066 13.2 0.2 0.066 13.2 0.1 2.3 2 1 0 2 2 2 0 NusB family DUF4481 PF14800.1 KZN91272.1 - 0.12 11.2 1.1 0.13 11.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) GAGA_bind PF06217.7 KZN91272.1 - 0.5 10.2 6.6 0.53 10.2 4.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF73-100_C PF11718.3 KZN91272.1 - 0.59 9.4 7.3 0.22 10.8 3.3 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term CDC45 PF02724.9 KZN91272.1 - 2.3 6.1 9.2 2.6 5.9 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PTPLA PF04387.9 KZN91273.1 - 6.9e-54 181.6 3.7 6.9e-54 181.6 2.6 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF4408 PF14364.1 KZN91274.1 - 0.38 10.3 1.7 0.93 9.1 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) DUF2823 PF11034.3 KZN91275.1 - 1.2e-30 105.4 11.3 1.3e-30 105.2 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) HSP9_HSP12 PF04119.7 KZN91275.1 - 0.1 12.6 3.9 0.26 11.3 2.7 1.6 1 1 1 2 2 2 0 Heat shock protein 9/12 APH PF01636.18 KZN91276.1 - 8.7e-20 71.4 0.0 1.4e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family dsrm PF00035.20 KZN91278.1 - 1.7e-05 25.3 0.0 5.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KZN91278.1 - 0.00027 21.1 0.1 0.00054 20.1 0.1 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.16 KZN91279.1 - 7e-44 147.0 29.1 4.7e-12 45.2 0.5 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KZN91279.1 - 3.5e-28 98.2 0.0 1.3e-17 64.1 0.0 4.2 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KZN91279.1 - 6.3e-05 22.9 0.0 0.0049 16.8 0.0 3.0 2 1 1 3 3 3 1 Prenyltransferase-like Pea-VEAacid PF08111.6 KZN91279.1 - 0.067 13.3 2.5 0.99 9.6 0.3 2.7 2 0 0 2 2 2 0 Pea-VEAacid family Zn_clus PF00172.13 KZN91280.1 - 0.0025 17.6 7.7 0.0061 16.4 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spectrin PF00435.16 KZN91280.1 - 0.071 13.3 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 Spectrin repeat SelP_N PF04592.9 KZN91280.1 - 7.4 5.8 12.8 0.47 9.7 3.2 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region ubiquitin PF00240.18 KZN91281.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KZN91281.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KZN91281.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KZN91281.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KZN91281.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KZN91281.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KZN91281.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KZN91281.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 KZN91281.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 KZN91281.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 KZN91281.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 KZN91281.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 KZN91281.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 KZN91281.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 KZN91281.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 KZN91281.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 KZN91281.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 KZN91281.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 KZN91281.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 KZN91281.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 KZN91281.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 KZN91282.1 - 4.2e-26 90.6 0.0 8.5e-26 89.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KZN91282.1 - 4.6e-20 71.4 5.4 1.8e-19 69.6 3.8 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KZN91282.1 - 7.9e-10 38.4 10.0 7.9e-10 38.4 6.9 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 KZN91282.1 - 2.1e-05 24.1 8.2 2.1e-05 24.1 5.7 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN91282.1 - 0.00019 21.0 9.1 0.00019 21.0 6.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN91282.1 - 0.0003 20.3 5.9 0.0003 20.3 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN91282.1 - 0.0005 20.0 9.5 0.0005 20.0 6.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN91282.1 - 0.0011 19.0 6.0 0.0011 19.0 4.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KZN91282.1 - 0.0012 18.5 2.7 0.0012 18.5 1.9 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KZN91282.1 - 0.0031 17.1 3.0 0.0031 17.1 2.1 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-Apc11 PF12861.2 KZN91282.1 - 0.0087 15.8 5.8 0.026 14.3 4.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_MLP1_2 PF07926.7 KZN91282.1 - 0.042 13.5 7.1 0.076 12.7 4.9 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Baculo_RING PF05883.6 KZN91282.1 - 0.16 11.8 2.5 0.45 10.3 1.7 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FTA4 PF13093.1 KZN91282.1 - 0.24 10.8 2.2 0.4 10.0 1.5 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-HC5HC2H PF13771.1 KZN91282.1 - 0.52 10.5 6.9 1.1 9.3 0.7 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 KZN91282.1 - 8.2 6.3 13.4 1.1 9.2 4.1 3.2 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Methyltransf_23 PF13489.1 KZN91283.1 - 1.6e-17 63.6 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN91283.1 - 3e-11 43.6 0.0 6.9e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN91283.1 - 6.9e-11 42.4 0.0 9.9e-09 35.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91283.1 - 4.6e-09 36.8 0.0 7.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN91283.1 - 3.2e-08 33.2 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KZN91283.1 - 3.9e-05 23.6 0.0 7.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN91283.1 - 4.4e-05 23.7 0.0 9.9e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.10 KZN91283.1 - 0.086 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Prp18 domain Fungal_trans PF04082.13 KZN91284.1 - 5.3e-22 77.9 0.2 8.7e-22 77.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91284.1 - 5.4e-09 35.8 11.6 1.2e-08 34.7 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 KZN91285.1 - 1.5e-168 561.2 2.6 1.9e-168 560.9 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KZN91285.1 - 6.8e-05 22.6 0.2 0.00057 19.6 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like GHL15 PF14885.1 KZN91285.1 - 1.5 9.0 5.5 0.19 11.9 0.6 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Alpha-amylase PF00128.19 KZN91286.1 - 6e-74 249.2 3.6 8.2e-74 248.8 2.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KZN91286.1 - 5.2e-30 103.3 0.0 1.4e-29 101.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 KZN91286.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Zn_clus PF00172.13 KZN91287.1 - 3.1e-06 26.9 8.4 5.7e-06 26.1 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.6 KZN91289.1 - 2.6e-20 71.8 0.3 5.5e-20 70.7 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KZN91289.1 - 4.7e-07 29.3 0.1 8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Homeobox domain FAD_binding_1 PF00667.15 KZN91291.1 - 8.1e-44 149.6 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KZN91291.1 - 8.2e-10 39.2 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.1 KZN91292.1 - 4.9e-54 183.4 45.9 6e-54 183.1 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN91292.1 - 1.8e-24 85.9 38.9 2.5e-24 85.4 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease CstA PF02554.9 KZN91293.1 - 0.26 9.8 10.2 3 6.3 7.1 2.0 1 1 0 1 1 1 0 Carbon starvation protein CstA Glyco_hydro_47 PF01532.15 KZN91294.1 - 1.7e-172 574.1 0.2 1.9e-172 573.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyoxal_oxid_N PF07250.6 KZN91294.1 - 0.023 13.7 0.2 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus DUF1680 PF07944.7 KZN91294.1 - 0.043 12.0 0.1 5 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Med20 PF08612.6 KZN91295.1 - 2.1e-78 262.5 0.0 2.5e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 KZN91296.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KZN91296.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KZN91296.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KZN91296.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KZN91296.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KZN91296.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KZN91296.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KZN91296.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KZN91296.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KZN91296.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KZN91296.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KZN91296.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 KZN91296.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KZN91296.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KZN91296.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 KZN91296.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KZN91296.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KZN91296.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 KZN91296.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 KZN91297.1 - 1.2e-16 60.1 2.2 1.2e-16 60.1 1.5 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KZN91297.1 - 1.3e-12 47.7 1.3 3.8e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KZN91297.1 - 0.11 12.5 5.0 1 9.4 0.1 3.1 2 2 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.16 KZN91297.1 - 0.21 11.0 9.5 0.088 12.3 1.2 2.7 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain H-kinase_dim PF02895.9 KZN91297.1 - 0.44 10.9 4.2 11 6.4 0.2 2.7 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain ATG16 PF08614.6 KZN91297.1 - 0.58 9.9 4.9 0.87 9.3 0.1 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DNA_repr_REX1B PF14966.1 KZN91297.1 - 1.5 9.2 4.5 1.3 9.4 0.0 3.0 4 1 0 4 4 4 0 DNA repair REX1-B CTD_bind PF04818.8 KZN91298.1 - 3.1e-18 65.7 0.0 7.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KZN91298.1 - 0.001 18.5 0.0 0.0029 17.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) DUF869 PF05911.6 KZN91298.1 - 0.0045 15.3 0.2 0.0059 14.8 0.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Muted PF14942.1 KZN91298.1 - 0.04 13.7 0.4 0.08 12.8 0.3 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.6 KZN91298.1 - 0.12 12.2 0.7 0.35 10.7 0.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Clathrin_lg_ch PF01086.12 KZN91299.1 - 1.9e-71 240.5 5.0 2.4e-71 240.2 3.5 1.1 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 KZN91300.1 - 8.4e-61 205.3 4.3 8.4e-61 205.3 3.0 2.4 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KZN91300.1 - 3.3e-46 156.9 0.1 8.5e-46 155.5 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KZN91300.1 - 7.4e-28 96.3 0.8 7.4e-28 96.3 0.5 2.6 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF922 PF06037.6 KZN91300.1 - 0.046 13.0 0.3 0.54 9.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF922) Rsbr_N PF08678.5 KZN91300.1 - 0.1 12.5 2.7 3.6 7.4 0.1 3.3 3 0 0 3 3 3 0 Rsbr N terminal MutS_IV PF05190.13 KZN91300.1 - 0.18 11.9 6.2 0.7 10.1 0.2 3.0 3 0 0 3 3 3 0 MutS family domain IV ThylakoidFormat PF11264.3 KZN91300.1 - 0.28 10.7 4.3 1.1 8.8 0.3 2.6 3 0 0 3 3 3 0 Thylakoid formation protein ABC_membrane PF00664.18 KZN91301.1 - 4e-47 160.9 10.7 5.5e-47 160.4 7.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KZN91301.1 - 9.5e-37 126.3 0.0 2.7e-36 124.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KZN91301.1 - 3.2e-05 23.2 0.0 0.0027 16.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN91301.1 - 0.00014 21.9 0.3 0.19 11.6 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN91301.1 - 0.0019 17.7 0.0 0.0053 16.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN91301.1 - 0.0036 17.3 0.1 0.012 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KZN91301.1 - 0.006 16.0 0.1 0.093 12.1 0.0 2.5 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.1 KZN91301.1 - 0.0095 16.7 0.1 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 KZN91301.1 - 0.011 14.3 0.2 0.048 12.2 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 KZN91301.1 - 0.016 15.3 0.4 0.11 12.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KZN91301.1 - 0.032 14.4 0.1 0.2 11.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KZN91301.1 - 0.038 13.1 0.0 0.08 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KZN91301.1 - 0.054 12.9 0.3 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KZN91301.1 - 0.064 12.6 0.6 0.51 9.7 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KZN91301.1 - 0.095 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KZN91301.1 - 0.11 12.4 3.5 0.21 11.5 0.4 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KZN91301.1 - 0.14 12.4 1.4 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain Nucleoside_tran PF01733.13 KZN91302.1 - 1.5e-41 142.5 16.8 3.1e-39 134.9 11.7 2.9 1 1 0 1 1 1 1 Nucleoside transporter DUF2975 PF11188.3 KZN91302.1 - 5.4 6.7 11.8 0.96 9.1 0.4 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2975) Gram_pos_anchor PF00746.16 KZN91302.1 - 6.2 6.7 6.1 2.1 8.2 0.0 2.9 2 0 0 2 2 2 0 Gram positive anchor p450 PF00067.17 KZN91303.1 - 2.5e-65 220.8 0.0 2.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3635 PF12330.3 KZN91304.1 - 5.3e-05 23.2 0.1 0.00014 21.8 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 KZN91305.1 - 0.00024 21.1 0.0 0.00084 19.4 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF1682 PF07946.9 KZN91306.1 - 2.3e-108 361.8 0.0 2.6e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Polysacc_deac_1 PF01522.16 KZN91307.1 - 1.6e-29 102.0 0.0 2.3e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Creatininase PF02633.9 KZN91307.1 - 3.9e-05 22.8 0.1 6.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Creatinine amidohydrolase Glyco_hydro_57 PF03065.10 KZN91307.1 - 0.0002 20.4 0.0 0.00097 18.1 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 PAC2 PF09754.4 KZN91307.1 - 0.064 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 PAC2 family Nitroreductase PF00881.19 KZN91308.1 - 5.4e-15 55.6 0.0 7.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Pkinase PF00069.20 KZN91309.1 - 3.1e-12 46.2 0.0 2.9e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91309.1 - 4.9e-09 35.6 0.0 5.5e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN91309.1 - 0.003 16.6 0.0 0.0097 14.9 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN91309.1 - 0.047 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 KZN91310.1 - 8.1e-22 77.4 75.7 2.8e-20 72.3 33.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 KZN91311.1 - 1.4e-11 44.9 0.0 1.8e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KZN91311.1 - 1.1e-08 35.1 0.1 6e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KZN91311.1 - 0.00012 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KZN91311.1 - 0.027 14.3 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain Tub_2 PF04525.7 KZN91312.1 - 1.2e-05 24.8 0.0 2.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Tubby C 2 adh_short PF00106.20 KZN91313.1 - 2.7e-06 27.3 0.9 3.9e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KZN91313.1 - 3.8e-05 23.7 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN91313.1 - 0.00016 21.1 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KZN91313.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KZN91313.1 - 0.0026 17.4 0.1 0.0026 17.4 0.0 1.7 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.12 KZN91313.1 - 0.011 14.6 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KZN91313.1 - 0.015 13.9 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KZN91313.1 - 0.055 12.3 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KZN91313.1 - 0.074 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase UPF0146 PF03686.8 KZN91313.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) adh_short PF00106.20 KZN91314.1 - 1e-07 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NUDIX PF00293.23 KZN91315.1 - 3.5e-18 65.5 0.0 4.2e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 KZN91315.1 - 0.069 12.5 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 NUDIX domain Antimicrobial_9 PF08104.6 KZN91315.1 - 0.081 12.7 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Ponericin L family RNase_H PF00075.19 KZN91318.1 - 5e-20 72.1 0.0 7.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KZN91318.1 - 0.00049 19.8 0.2 0.012 15.3 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like Ins_P5_2-kin PF06090.7 KZN91319.1 - 3.1e-73 246.5 0.0 3.7e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 KZN91320.1 - 7.6e-32 108.8 0.2 8.7e-32 108.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 PI-PLC-X PF00388.14 KZN91321.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain COX7a PF02238.10 KZN91322.1 - 0.09 12.5 1.0 0.22 11.2 0.7 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Fungal_trans PF04082.13 KZN91323.1 - 0.0022 16.9 0.1 0.045 12.6 0.0 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epsilon_antitox PF08998.6 KZN91323.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Aminotran_5 PF00266.14 KZN91324.1 - 4.4e-10 38.8 0.0 4.3e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KZN91324.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 KZN91325.1 - 4.5e-140 466.8 0.0 5.5e-140 466.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase YEATS PF03366.11 KZN91326.1 - 2.5e-36 123.2 1.6 3.8e-36 122.6 1.1 1.3 1 0 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 KZN91327.1 - 4.5e-12 46.3 0.0 1.2e-10 41.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN91327.1 - 4.7e-07 29.4 0.0 1.6e-06 27.7 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN91327.1 - 4.3e-05 22.3 0.0 0.00024 19.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN91327.1 - 0.0019 18.1 0.0 0.0059 16.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KZN91327.1 - 0.019 13.9 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KZN91327.1 - 0.08 11.8 0.0 0.51 9.1 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 KZN91327.1 - 0.088 12.0 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family SYF2 PF08231.7 KZN91328.1 - 2.7e-54 183.4 14.5 2.7e-54 183.4 10.0 2.0 2 0 0 2 2 2 1 SYF2 splicing factor Pneumo_att_G PF05539.6 KZN91328.1 - 1.1 8.5 7.2 1.4 8.1 5.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Velvet PF11754.3 KZN91330.1 - 2.6e-62 210.0 0.0 3.9e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Velvet factor PRP38_assoc PF12871.2 KZN91330.1 - 0.00012 22.5 7.0 0.00012 22.5 4.9 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 KZN91330.1 - 0.34 10.6 19.1 0.78 9.4 13.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SSURE PF11966.3 KZN91331.1 - 0.037 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Fibronectin-binding repeat Ribosomal_L12 PF00542.14 KZN91332.1 - 3.3e-18 65.4 4.4 3.6e-17 62.1 2.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Cpn60_TCP1 PF00118.19 KZN91333.1 - 6.6e-125 417.4 1.4 7.4e-125 417.3 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.13 KZN91334.1 - 2.7e-21 76.1 0.0 2.7e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 KZN91334.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_MA_2 PF13485.1 KZN91334.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 KZN91334.1 - 0.15 11.7 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF955) PH_10 PF15411.1 KZN91335.1 - 6.2e-23 81.1 0.0 1.1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KZN91335.1 - 1.9e-13 50.3 0.0 3.4e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KZN91335.1 - 2.7e-08 33.4 8.5 6.2e-08 32.3 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KZN91335.1 - 4.2e-07 29.8 0.0 8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 KZN91335.1 - 0.0074 15.9 4.7 0.013 15.1 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN91335.1 - 0.0084 15.8 7.4 0.015 15.0 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KZN91335.1 - 0.017 15.2 3.7 0.032 14.3 2.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN91335.1 - 0.028 14.4 6.8 0.052 13.5 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN91335.1 - 0.13 11.9 6.8 0.24 11.0 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KZN91335.1 - 5.1 7.1 7.0 9.7 6.2 4.8 1.5 1 0 0 1 1 1 0 RING-like domain E1_dh PF00676.15 KZN91337.1 - 4.2e-114 380.3 0.5 5e-114 380.0 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KZN91337.1 - 0.00081 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Mitofilin PF09731.4 KZN91338.1 - 0.4 9.2 5.9 0.68 8.5 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein S4 PF01479.20 KZN91339.1 - 6.2e-16 57.5 0.0 1.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KZN91339.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain Glyco_hydro_11 PF00457.12 KZN91339.1 - 0.095 12.0 0.5 0.16 11.3 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 DUF4355 PF14265.1 KZN91339.1 - 0.22 11.4 23.9 0.82 9.6 10.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF3636 PF12331.3 KZN91340.1 - 4.9e-56 188.4 0.3 1e-55 187.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Atg14 PF10186.4 KZN91340.1 - 0.15 10.9 5.3 0.25 10.2 3.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KZN91340.1 - 1 8.3 5.6 1.8 7.5 3.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CTP_transf_1 PF01148.15 KZN91341.1 - 2.2e-81 273.3 26.8 2.6e-81 273.0 18.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 KZN91342.1 - 3.1e-13 49.3 0.0 2.5e-10 39.9 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain GST_N_3 PF13417.1 KZN91343.1 - 2.1e-22 79.1 0.6 4.9e-22 77.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN91343.1 - 5.8e-15 55.0 1.0 1.3e-14 53.9 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN91343.1 - 5.6e-07 29.6 0.0 9.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN91343.1 - 1.2e-06 28.2 0.3 4.2e-06 26.5 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN91343.1 - 0.00014 21.8 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN91343.1 - 0.00087 19.7 0.1 0.0024 18.3 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Fructosamin_kin PF03881.9 KZN91344.1 - 8.2e-73 244.8 0.0 1.1e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Arm PF00514.18 KZN91344.1 - 1.2e-17 63.0 8.5 3.1e-05 23.6 0.0 8.3 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat APH PF01636.18 KZN91344.1 - 9.2e-05 22.2 0.0 0.00031 20.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT PF02985.17 KZN91344.1 - 0.00013 21.7 0.8 5.4 7.3 0.1 5.7 4 1 1 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KZN91344.1 - 0.00099 19.3 4.2 0.088 13.1 0.0 5.2 6 1 1 7 7 7 1 HEAT repeats Ric8 PF10165.4 KZN91344.1 - 0.031 13.0 0.1 4.7 5.9 0.0 3.6 4 0 0 4 4 4 0 Guanine nucleotide exchange factor synembryn Cyclin PF08613.6 KZN91345.1 - 4.3e-30 105.1 0.2 1.3e-29 103.5 0.2 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN91345.1 - 3.7e-05 23.2 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain dCMP_cyt_deam_1 PF00383.17 KZN91346.1 - 5.3e-05 22.8 0.6 0.25 10.9 0.1 2.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Na_Ca_ex PF01699.19 KZN91347.1 - 4.7e-29 100.7 29.9 4.9e-15 55.3 10.7 2.4 2 1 1 3 3 3 2 Sodium/calcium exchanger protein UCH PF00443.24 KZN91348.1 - 3e-50 170.8 0.0 4.9e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN91348.1 - 5.8e-18 65.3 0.0 4.5e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 KZN91348.1 - 0.048 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated zf-C3HC4_2 PF13923.1 KZN91349.1 - 4.9e-08 32.8 9.0 8.1e-08 32.1 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN91349.1 - 3.1e-07 29.9 7.7 5.3e-07 29.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN91349.1 - 8.3e-07 28.7 8.2 1.4e-06 28.0 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KZN91349.1 - 3.1e-06 26.7 5.8 5.4e-06 25.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KZN91349.1 - 6.2e-06 25.9 5.4 3.9e-05 23.4 4.1 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KZN91349.1 - 2.2e-05 24.0 5.5 4.2e-05 23.1 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KZN91349.1 - 0.011 15.4 5.0 0.014 15.0 2.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger GEMIN8 PF15348.1 KZN91349.1 - 0.026 14.5 0.4 0.026 14.5 0.3 2.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 zf-MIZ PF02891.15 KZN91349.1 - 0.88 9.1 10.5 2.4 7.7 7.2 1.8 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger ERG4_ERG24 PF01222.12 KZN91350.1 - 1.1e-140 468.9 20.1 1.3e-140 468.7 13.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DLH PF01738.13 KZN91351.1 - 2e-30 105.6 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KZN91351.1 - 3.5e-07 30.0 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KZN91351.1 - 0.0045 16.7 0.1 0.2 11.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KZN91351.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 KZN91351.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KZN91351.1 - 0.12 12.2 0.0 9.5 6.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF2305 PF10230.4 KZN91351.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chs3p PF12271.3 KZN91352.1 - 8.7e-107 356.4 4.7 1e-106 356.2 3.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit BC10 PF06726.7 KZN91353.1 - 1.6e-15 56.8 9.4 2.6e-15 56.1 6.5 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF2203 PF09969.4 KZN91354.1 - 5 7.3 6.4 0.76 10.0 0.5 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Na_H_Exchanger PF00999.16 KZN91355.1 - 2.5e-42 144.7 20.7 3.3e-42 144.3 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LMBR1 PF04791.11 KZN91355.1 - 0.0035 15.9 0.5 0.0084 14.7 0.3 1.5 1 0 0 1 1 1 1 LMBR1-like membrane protein Cauli_VI PF01693.11 KZN91356.1 - 4.9e-33 112.8 5.0 1.1e-15 57.2 0.8 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KZN91356.1 - 4.3e-27 95.0 0.0 6.8e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 RNase H Homeobox_KN PF05920.6 KZN91356.1 - 0.1 12.3 0.4 0.29 10.8 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain NMO PF03060.10 KZN91357.1 - 8.1e-43 146.8 6.5 1.3e-41 142.8 4.5 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KZN91357.1 - 1.5e-08 33.9 2.1 2.4e-08 33.2 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KZN91357.1 - 1.9e-08 33.5 1.0 3e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KZN91357.1 - 0.0039 16.1 0.5 0.0064 15.4 0.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GspH PF12019.3 KZN91357.1 - 0.011 15.8 1.2 0.78 9.9 0.1 2.4 2 0 0 2 2 2 0 Type II transport protein GspH Ribul_P_3_epim PF00834.14 KZN91357.1 - 0.017 14.2 0.6 0.83 8.7 0.1 2.2 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Ribosomal_S9 PF00380.14 KZN91357.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S9/S16 FMN_dh PF01070.13 KZN91358.1 - 9e-108 360.2 0.0 1.1e-107 360.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KZN91358.1 - 1.8e-21 75.7 0.0 6.2e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KZN91358.1 - 9.8e-07 27.9 1.4 0.002 17.0 0.1 3.0 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KZN91358.1 - 3.7e-05 22.8 0.0 6.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KZN91358.1 - 0.021 14.1 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein ATP11 PF06644.6 KZN91358.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein DUF998 PF06197.8 KZN91359.1 - 0.029 13.6 3.6 0.37 10.0 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF202 PF02656.10 KZN91359.1 - 0.052 13.7 8.1 0.47 10.7 5.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) 6PF2K PF01591.13 KZN91360.1 - 5.4e-71 238.2 0.0 1.4e-50 171.4 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KZN91360.1 - 2.3e-29 102.5 0.1 5.5e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KZN91360.1 - 5.4e-09 36.0 0.0 0.00035 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN91360.1 - 0.00088 20.0 0.0 0.004 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KZN91360.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KZN91360.1 - 0.077 12.0 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DSBA PF01323.15 KZN91361.1 - 1.8e-32 112.4 0.1 3.4e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain 3-alpha PF03475.9 KZN91361.1 - 0.034 13.8 0.1 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 3-alpha domain VTC PF09359.5 KZN91362.1 - 4.1e-88 295.0 0.9 4.7e-88 294.8 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KZN91362.1 - 1.7e-21 77.2 9.6 1.6e-18 67.4 4.9 3.3 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KZN91362.1 - 9.4e-11 41.7 4.8 1.1e-10 41.5 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PCNP PF15473.1 KZN91362.1 - 0.025 14.9 0.3 0.062 13.6 0.2 1.6 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DUF3815 PF12821.2 KZN91362.1 - 0.039 13.8 0.3 0.059 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) Bax1-I PF01027.15 KZN91362.1 - 0.046 13.3 0.7 0.078 12.5 0.5 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 NUDIX PF00293.23 KZN91363.1 - 2.4e-15 56.3 0.1 4.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.18 KZN91364.1 - 6.8e-05 22.8 0.1 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KZN91364.1 - 0.084 12.8 0.2 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W AAA_32 PF13654.1 KZN91364.1 - 0.097 11.3 0.1 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ant_C PF05586.6 KZN91365.1 - 0.04 14.3 0.1 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 Anthrax receptor C-terminus region HrcA_DNA-bdg PF03444.10 KZN91365.1 - 0.1 12.0 0.2 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding OmpH PF03938.9 KZN91365.1 - 0.22 11.4 11.0 0.45 10.4 7.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.11 KZN91366.1 - 3.6e-45 154.2 13.4 3.6e-45 154.2 9.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91366.1 - 3.8e-07 29.0 4.2 7.6e-07 28.0 3.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KZN91366.1 - 0.00012 20.4 1.0 0.00018 19.8 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 KZN91368.1 - 2e-17 62.3 5.3 6.5e-09 35.3 0.1 7.2 8 0 0 8 8 8 3 WD domain, G-beta repeat DUF3639 PF12341.3 KZN91368.1 - 1.2e-09 37.9 0.1 1.2e-09 37.9 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KZN91368.1 - 3.8e-07 29.2 0.0 6e-06 25.3 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 KZN91368.1 - 0.019 13.2 0.2 1.1 7.5 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain DNA_pol_alpha_N PF12254.3 KZN91368.1 - 0.024 14.4 3.0 0.058 13.2 2.1 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 KZN91368.1 - 0.23 9.2 0.5 0.7 7.6 0.1 1.8 2 1 1 3 3 3 0 IKI3 family MMS1_N PF10433.4 KZN91368.1 - 0.28 9.2 0.0 2.6 6.0 0.0 2.3 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF499 PF04465.7 KZN91368.1 - 0.46 7.9 0.0 0.65 7.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) ILVD_EDD PF00920.16 KZN91369.1 - 3.3e-167 557.0 0.9 3.8e-167 556.8 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family p450 PF00067.17 KZN91370.1 - 3.9e-13 48.7 0.0 7.3e-13 47.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 RNA12 PF10443.4 KZN91371.1 - 2e-164 547.2 0.0 3e-164 546.6 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 KZN91371.1 - 2.2e-06 27.5 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 KZN91371.1 - 3.5e-05 23.3 0.0 0.00011 21.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIR_2 PF13676.1 KZN91371.1 - 0.00076 19.5 0.1 2.4 8.3 0.0 4.1 4 0 0 4 4 4 1 TIR domain DUF2487 PF10673.4 KZN91371.1 - 0.0032 17.2 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_16 PF13191.1 KZN91371.1 - 0.0034 17.4 0.0 0.0087 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RRM_6 PF14259.1 KZN91371.1 - 0.0043 17.0 0.0 0.078 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 KZN91371.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3128 PF11326.3 KZN91372.1 - 3.1e-29 100.9 1.5 3.1e-29 100.9 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Glu_synthase PF01645.12 KZN91374.1 - 1.1e-158 528.0 0.0 1.5e-158 527.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KZN91374.1 - 4e-139 463.3 0.0 5.4e-139 462.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KZN91374.1 - 1.3e-117 392.1 0.0 2.1e-117 391.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KZN91374.1 - 1.5e-67 226.5 1.8 2.8e-67 225.6 1.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KZN91374.1 - 7.1e-22 77.1 0.0 1.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KZN91374.1 - 7.8e-18 65.0 0.0 3.3e-17 63.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN91374.1 - 5.6e-10 39.6 1.3 0.00062 19.8 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN91374.1 - 8.3e-09 35.3 0.0 3.6e-08 33.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN91374.1 - 1.3e-07 31.8 0.1 0.00049 20.4 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN91374.1 - 2.5e-06 26.6 1.0 0.00019 20.4 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KZN91374.1 - 4e-06 26.1 0.2 6.6e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KZN91374.1 - 8.7e-06 24.8 0.1 0.0002 20.3 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KZN91374.1 - 4.6e-05 22.0 0.3 0.00012 20.7 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KZN91374.1 - 0.00014 21.0 0.3 0.00029 20.0 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KZN91374.1 - 0.00031 20.3 0.1 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KZN91374.1 - 0.00085 18.4 0.1 0.0016 17.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KZN91374.1 - 0.003 16.7 0.4 0.015 14.4 0.2 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KZN91374.1 - 0.0041 17.3 1.3 3.4 7.9 0.1 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding DJ-1_PfpI PF01965.19 KZN91374.1 - 0.042 13.3 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 DJ-1/PfpI family NAD_binding_9 PF13454.1 KZN91374.1 - 0.047 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMN_dh PF01070.13 KZN91374.1 - 0.053 12.3 1.1 0.19 10.5 0.5 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FMO-like PF00743.14 KZN91374.1 - 0.073 11.2 0.1 3.3 5.7 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 KZN91374.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MADF_DNA_bdg PF10545.4 KZN91374.1 - 0.3 11.3 0.4 0.74 10.0 0.3 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GIDA PF01134.17 KZN91374.1 - 0.71 8.6 5.7 0.074 11.8 0.4 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Apc15p PF05841.6 KZN91375.1 - 6.3e-28 98.0 2.1 6.3e-28 98.0 1.4 2.2 2 0 0 2 2 2 1 Apc15p protein SNARE PF05739.14 KZN91376.1 - 8.4e-07 28.5 1.3 1.1e-06 28.2 0.9 1.2 1 0 0 1 1 1 1 SNARE domain OPT PF03169.10 KZN91377.1 - 3.7e-137 458.3 46.5 4.3e-137 458.2 32.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 KZN91377.1 - 0.016 14.2 0.5 0.044 12.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.4 KZN91377.1 - 8.6 4.8 10.2 0.73 8.3 1.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) HSP70 PF00012.15 KZN91378.1 - 5.6e-272 903.0 7.3 6.3e-272 902.8 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KZN91378.1 - 7.4e-18 64.2 0.1 3.5e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KZN91378.1 - 0.00057 19.7 1.4 0.44 10.4 0.0 3.1 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KZN91378.1 - 0.0014 18.2 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KZN91378.1 - 0.008 15.4 0.1 0.81 8.9 0.0 2.5 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 KZN91378.1 - 0.0089 15.1 0.1 0.035 13.2 0.0 1.9 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase PMBR PF09373.5 KZN91378.1 - 0.036 14.0 0.1 0.34 10.9 0.0 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat StbA PF06406.6 KZN91378.1 - 0.041 12.8 0.0 0.083 11.8 0.0 1.5 1 0 0 1 1 1 0 StbA protein Macoilin PF09726.4 KZN91378.1 - 0.081 11.1 2.2 0.12 10.6 0.4 1.9 2 0 0 2 2 2 0 Transmembrane protein DUF2665 PF11654.3 KZN91379.1 - 1.7e-06 27.4 0.2 5.9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) DUF2012 PF09430.5 KZN91380.1 - 9e-31 106.2 0.0 1.2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 KZN91381.1 - 1.6e-08 34.2 4.1 1.6e-08 34.2 2.8 2.3 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 KZN91381.1 - 0.00014 21.9 19.3 0.00014 21.9 13.4 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.27 KZN91382.1 - 1.2e-10 40.7 15.9 0.00085 19.1 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Mito_carr PF00153.22 KZN91383.1 - 3.2e-53 177.3 2.5 1.4e-17 63.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.1 KZN91383.1 - 0.0043 16.6 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Putative AphA-like transcriptional regulator Ras PF00071.17 KZN91384.1 - 7.5e-66 220.4 0.5 8.8e-66 220.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN91384.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN91384.1 - 2e-16 59.7 0.1 2.4e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN91384.1 - 1.8e-05 23.9 0.1 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KZN91384.1 - 4.1e-05 23.1 0.1 8.4e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KZN91384.1 - 6.3e-05 22.9 0.0 9.1e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KZN91384.1 - 0.00031 20.9 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KZN91384.1 - 0.00073 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KZN91384.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 KZN91384.1 - 0.0041 16.4 0.0 0.029 13.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KZN91384.1 - 0.0092 15.1 0.0 0.024 13.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN91384.1 - 0.02 14.8 0.1 0.084 12.8 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KZN91384.1 - 0.03 14.2 0.1 0.09 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KZN91384.1 - 0.032 13.2 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 KZN91384.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KZN91384.1 - 0.053 13.2 0.1 0.1 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KZN91384.1 - 0.056 13.7 0.1 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KZN91384.1 - 0.086 12.3 0.1 0.89 9.0 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M1 PF01433.15 KZN91385.1 - 6.9e-120 400.7 0.3 1.2e-112 376.8 0.0 2.4 3 0 0 3 3 3 2 Peptidase family M1 ERAP1_C PF11838.3 KZN91385.1 - 2.5e-77 260.2 0.1 3.7e-77 259.7 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KZN91385.1 - 5.9e-19 68.3 0.0 1.9e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 KZN91386.1 - 3.8e-75 251.7 0.0 5.1e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KZN91386.1 - 2.6e-17 62.5 9.6 2.6e-17 62.5 6.6 2.6 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KZN91386.1 - 3.5e-12 46.7 0.0 5.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KZN91386.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Tfb4 PF03850.9 KZN91386.1 - 0.29 10.3 4.8 0.53 9.4 3.4 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 DZR PF12773.2 KZN91386.1 - 0.56 10.0 21.1 3.2 7.6 3.7 3.3 2 1 0 2 2 2 0 Double zinc ribbon PUF PF00806.14 KZN91388.1 - 2.5e-34 114.7 2.1 2.1e-05 23.7 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat TPT PF03151.11 KZN91389.1 - 3e-35 121.1 3.5 3e-35 121.1 2.4 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KZN91389.1 - 1.3e-05 24.3 16.9 8.2e-05 21.6 11.7 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KZN91389.1 - 0.00013 21.9 32.9 0.00058 19.9 4.7 3.0 4 0 0 4 4 4 2 EamA-like transporter family Molybdopterin PF00384.17 KZN91390.1 - 2.6e-69 234.0 0.0 1.2e-66 225.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KZN91390.1 - 3.1e-19 67.9 0.1 8.6e-19 66.4 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KZN91390.1 - 2e-14 53.1 0.1 5.3e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KZN91390.1 - 1.2e-13 50.9 0.1 3.3e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer4 PF00037.22 KZN91390.1 - 0.11 12.1 1.0 3 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 KZN91390.1 - 0.19 11.6 2.4 0.23 11.3 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 KZN91390.1 - 0.28 11.0 2.1 4.5 7.1 1.4 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster XRCC4 PF06632.7 KZN91391.1 - 2.2e-09 36.6 1.9 2.9e-09 36.2 1.3 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pox_A11 PF05061.8 KZN91391.1 - 0.042 12.9 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF1759 PF03564.10 KZN91391.1 - 0.077 12.8 0.5 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Tropomyosin_1 PF12718.2 KZN91391.1 - 0.85 9.4 7.3 0.042 13.7 1.3 1.6 2 0 0 2 2 2 0 Tropomyosin like zf-H2C2 PF09337.5 KZN91393.1 - 0.018 14.4 0.4 0.031 13.6 0.3 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ER_lumen_recept PF00810.13 KZN91394.1 - 6.7e-56 188.8 7.8 1.1e-55 188.1 5.4 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KZN91394.1 - 0.0084 15.6 16.8 0.48 10.0 0.2 4.2 3 1 2 5 5 5 3 PQ loop repeat DUF382 PF04037.8 KZN91396.1 - 1.4e-62 209.2 1.1 3.1e-62 208.1 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KZN91396.1 - 2.1e-21 75.0 4.7 5.8e-21 73.6 3.3 1.8 1 0 0 1 1 1 1 PSP Ribonuclease_3 PF00636.21 KZN91397.1 - 2.4e-16 60.2 0.0 6.4e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN91397.1 - 2.1e-12 47.1 0.0 4.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like tRNA-synt_2c PF01411.14 KZN91399.1 - 0.011 14.0 0.0 0.016 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) APH PF01636.18 KZN91400.1 - 0.0042 16.8 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Cupin_3 PF05899.7 KZN91400.1 - 0.12 11.7 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Bromodomain PF00439.20 KZN91401.1 - 1.9e-15 56.5 0.0 3.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain CKS PF01111.14 KZN91402.1 - 6.9e-37 125.1 0.5 6.9e-37 125.1 0.3 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KZN91402.1 - 5.4 7.2 6.5 0.94 9.6 0.2 2.5 3 0 0 3 3 3 0 APC 15 residue motif DUF3844 PF12955.2 KZN91404.1 - 1.1e-37 128.2 5.0 1.9e-37 127.4 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KZN91404.1 - 0.41 10.8 8.5 1.6 8.9 5.9 1.9 1 1 0 1 1 1 0 EGF-like domain zf-RING_2 PF13639.1 KZN91405.1 - 2.8e-13 49.4 6.1 4.5e-13 48.8 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KZN91405.1 - 1.1e-07 31.3 3.9 1.8e-07 30.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN91405.1 - 7.9e-07 29.1 4.6 1.8e-06 27.9 3.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KZN91405.1 - 2.1e-06 27.3 3.8 3.2e-06 26.7 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KZN91405.1 - 7.4e-06 25.8 5.7 1.2e-05 25.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN91405.1 - 7.7e-05 22.2 2.5 0.00012 21.6 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN91405.1 - 0.0018 18.0 3.0 0.0049 16.6 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KZN91405.1 - 0.03 13.9 6.4 0.049 13.2 4.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KZN91405.1 - 0.045 13.6 4.9 0.091 12.6 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KZN91405.1 - 0.13 11.9 5.5 0.25 11.0 3.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KZN91405.1 - 0.65 10.0 5.6 1.2 9.2 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KZN91405.1 - 0.67 9.9 3.5 1.8 8.6 2.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Pro_isomerase PF00160.16 KZN91406.1 - 4.5e-46 156.8 1.2 5.1e-46 156.7 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 KZN91407.1 - 2e-215 716.2 0.0 3.3e-215 715.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KZN91407.1 - 3.7e-17 61.9 0.5 8e-17 60.8 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KZN91407.1 - 0.0011 18.6 1.1 0.0025 17.4 0.8 1.7 1 0 0 1 1 1 1 DHHA1 domain HSP70 PF00012.15 KZN91408.1 - 7.9e-228 757.2 7.1 8.8e-228 757.0 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KZN91408.1 - 1.9e-16 59.6 0.6 6.6e-16 57.8 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KZN91408.1 - 0.00056 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BACON PF13004.2 KZN91408.1 - 0.043 14.0 0.0 0.2 11.8 0.0 2.2 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal ATP-synt_DE PF00401.15 KZN91408.1 - 0.077 12.8 0.4 2.5 8.0 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NAF PF03822.9 KZN91408.1 - 0.37 10.5 3.8 0.86 9.3 0.2 2.7 2 0 0 2 2 2 0 NAF domain RRF PF01765.14 KZN91409.1 - 3.3e-39 133.9 1.1 4.5e-39 133.5 0.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor SpoIIIAH PF12685.2 KZN91409.1 - 0.029 13.8 2.0 0.051 13.0 1.4 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein PcfJ PF14284.1 KZN91409.1 - 0.049 13.1 1.3 0.11 11.9 0.9 1.6 1 0 0 1 1 1 0 PcfJ-like protein Syntaxin PF00804.20 KZN91409.1 - 0.56 10.4 5.1 2.3 8.4 0.7 2.4 2 0 0 2 2 2 0 Syntaxin DUF1104 PF06518.6 KZN91409.1 - 0.82 9.8 6.4 1.8 8.7 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Fungal_trans PF04082.13 KZN91411.1 - 8.5e-08 31.3 0.0 1.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91411.1 - 2.9e-06 27.0 8.5 5.2e-06 26.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 KZN91412.1 - 2.1e-06 27.6 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 KZN91413.1 - 2.3e-43 147.8 0.0 3.4e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KZN91413.1 - 4.7e-27 93.9 0.0 1.1e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KZN91413.1 - 1.2e-19 69.9 0.0 2.8e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KZN91413.1 - 5.8e-11 42.3 0.0 1.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KZN91413.1 - 2.2e-07 30.6 0.2 1.4e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KZN91413.1 - 2.6e-06 27.3 0.1 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN91413.1 - 0.00036 21.0 0.0 0.0014 19.1 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KZN91413.1 - 0.0058 16.0 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 KZN91413.1 - 0.012 15.4 0.1 3.2 7.5 0.1 2.5 1 1 1 2 2 2 0 Dynamin family Thiolase_N PF00108.18 KZN91414.1 - 6.2e-96 320.4 0.2 8.4e-96 319.9 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN91414.1 - 1.2e-43 147.4 2.8 1.2e-43 147.3 0.9 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KZN91414.1 - 2.9e-05 23.6 2.7 2.9e-05 23.6 1.8 2.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KZN91414.1 - 0.16 11.6 2.8 0.3 10.7 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.17 KZN91415.1 - 3.4e-47 160.9 1.0 4.5e-47 160.5 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter LMBR1 PF04791.11 KZN91417.1 - 5.6e-20 71.3 11.2 8.6e-20 70.7 1.1 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein Anemone_cytotox PF06369.7 KZN91417.1 - 0.056 12.8 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 Sea anemone cytotoxic protein CPSF_A PF03178.10 KZN91418.1 - 3.7e-101 338.4 0.0 1.3e-100 336.6 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KZN91418.1 - 4.4e-05 21.8 0.2 0.13 10.3 0.0 2.5 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term NDT80_PhoG PF05224.7 KZN91419.1 - 1.5e-41 142.4 0.2 4e-41 141.0 0.0 1.8 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 KZN91420.1 - 2.1e-58 197.6 0.0 3e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KZN91420.1 - 0.0013 18.7 0.0 0.0052 16.7 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 KZN91420.1 - 0.0023 17.5 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.1 KZN91420.1 - 0.011 15.7 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 KZN91421.1 - 1e-14 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.17 KZN91422.1 - 2.3e-155 517.4 0.6 2.8e-155 517.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KZN91423.1 - 8.9e-53 179.3 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91423.1 - 7.2e-38 130.1 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN91423.1 - 4.7e-06 25.7 0.1 0.057 12.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN91423.1 - 1.7e-05 23.8 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN91423.1 - 0.00097 19.1 0.1 0.0038 17.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN91423.1 - 0.0033 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KZN91423.1 - 0.019 14.0 2.0 0.078 12.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN91423.1 - 0.059 13.4 0.1 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91423.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_4 PF13147.1 KZN91424.1 - 3.5e-13 50.2 7.7 3.8e-12 46.8 5.4 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN91424.1 - 2.6e-11 43.7 0.1 4.9e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KZN91424.1 - 1e-06 28.2 0.4 2.2e-06 27.1 0.0 1.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN91424.1 - 7.4e-05 22.4 0.0 0.00022 20.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 KZN91425.1 - 3.8e-17 62.0 30.3 5.6e-17 61.4 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN91425.1 - 1.4e-10 40.8 5.4 1.4e-10 40.8 3.7 2.5 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Peptidase_S10 PF00450.17 KZN91426.1 - 6.2e-106 355.0 0.7 7.4e-106 354.7 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase YtxH PF12732.2 KZN91427.1 - 0.067 13.5 0.7 5.5 7.4 0.1 3.2 3 0 0 3 3 3 0 YtxH-like protein RCR PF12273.3 KZN91428.1 - 4.5e-26 91.9 13.6 6.2e-26 91.4 9.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 KZN91428.1 - 0.052 13.1 0.4 0.072 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Rhabdo_glycop PF00974.13 KZN91428.1 - 0.15 10.2 0.1 0.19 9.8 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Sld5 PF05916.6 KZN91429.1 - 1.2e-10 41.6 0.3 1.7e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein MxiH PF09392.5 KZN91429.1 - 0.43 11.1 2.2 1 10.0 0.0 2.1 1 1 1 2 2 2 0 Type III secretion needle MxiH like Cullin PF00888.17 KZN91430.1 - 2.2e-127 426.0 9.6 3.2e-127 425.5 6.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KZN91430.1 - 1.8e-28 98.1 0.5 7.5e-28 96.1 0.3 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-DNL PF05180.7 KZN91431.1 - 5.4e-29 99.7 0.4 8.3e-29 99.1 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KZN91431.1 - 0.00028 20.3 0.3 0.00051 19.4 0.2 1.4 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.8 KZN91431.1 - 0.0043 16.7 0.2 0.0074 15.9 0.2 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like TFIIS_C PF01096.13 KZN91431.1 - 0.0054 16.3 2.7 0.4 10.3 0.3 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) E7 PF00527.13 KZN91431.1 - 0.014 15.5 1.0 0.014 15.5 0.7 2.2 1 1 1 2 2 2 0 E7 protein, Early protein zf-DNA_Pol PF08996.5 KZN91431.1 - 0.017 14.5 0.5 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF2039 PF10217.4 KZN91431.1 - 0.052 13.5 0.8 0.083 12.9 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) HypA PF01155.14 KZN91431.1 - 0.086 12.5 0.5 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KZN91431.1 - 0.088 12.7 1.8 0.24 11.3 1.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 KZN91431.1 - 0.16 11.4 1.5 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.2 KZN91431.1 - 0.59 9.9 6.4 12 5.7 4.3 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Pheromone PF08015.6 KZN91431.1 - 6.8 7.5 6.3 4.3 8.2 2.1 2.1 1 1 1 2 2 2 0 Fungal mating-type pheromone DRIM PF07539.7 KZN91432.1 - 4e-45 152.6 0.0 1.6e-44 150.7 0.0 2.2 2 0 0 2 2 2 1 Down-regulated in metastasis BP28CT PF08146.7 KZN91432.1 - 0.0026 17.4 0.4 0.065 12.9 0.0 3.7 3 0 0 3 3 3 1 BP28CT (NUC211) domain HEAT PF02985.17 KZN91432.1 - 0.24 11.5 0.0 0.24 11.5 0.0 5.8 7 0 0 7 7 7 0 HEAT repeat Delta_lysin PF05372.6 KZN91432.1 - 0.34 10.2 0.6 41 3.6 0.0 3.2 3 0 0 3 3 3 0 Delta lysin family CwfJ_C_1 PF04677.10 KZN91433.1 - 6.4e-24 83.9 0.0 2e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KZN91433.1 - 7e-22 77.7 0.3 1.2e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Rhodanese PF00581.15 KZN91435.1 - 8.3e-13 48.6 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.8 KZN91436.1 - 1.2e-72 244.9 12.7 1.6e-72 244.5 8.8 1.2 1 0 0 1 1 1 1 DNA polymerase phi SGT1 PF07093.6 KZN91436.1 - 4.9e-05 21.9 18.2 0.00034 19.1 12.1 2.5 2 0 0 2 2 2 1 SGT1 protein SDA1 PF05285.7 KZN91436.1 - 0.11 11.6 21.2 0.32 10.2 14.7 1.7 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KZN91436.1 - 4.3 5.7 19.0 7.9 4.8 13.2 1.3 1 0 0 1 1 1 0 Daxx Family MOSC_N PF03476.11 KZN91437.1 - 8.1e-22 77.1 0.0 4.9e-21 74.6 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KZN91437.1 - 1e-16 60.6 0.0 1.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 MOSC domain Peptidase_C15 PF01470.12 KZN91438.1 - 8.6e-13 48.5 0.0 1.8e-05 24.6 0.0 2.7 2 1 0 2 2 2 2 Pyroglutamyl peptidase p450 PF00067.17 KZN91439.1 - 3.1e-39 134.7 0.0 3.9e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 QCR10 PF09796.4 KZN91439.1 - 0.094 12.3 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Mad3_BUB1_I PF08311.7 KZN91441.1 - 2.5e-43 146.8 0.0 5.4e-43 145.7 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KZN91441.1 - 6e-12 45.2 0.0 3.2e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91441.1 - 0.0011 18.1 0.0 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 KZN91441.1 - 0.003 17.4 0.0 0.062 13.2 0.0 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 AP_endonuc_2 PF01261.19 KZN91442.1 - 1.1e-24 86.8 0.0 1.7e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HGTP_anticodon2 PF12745.2 KZN91442.1 - 6.2 5.8 9.2 0.21 10.7 1.6 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs TPT PF03151.11 KZN91443.1 - 6.3e-30 103.8 11.4 6.3e-30 103.8 7.9 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KZN91443.1 - 4.6e-05 23.4 30.7 0.002 18.1 7.5 3.0 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KZN91443.1 - 0.0014 17.6 20.3 0.0014 17.6 14.1 1.6 2 0 0 2 2 2 1 UAA transporter family Glyco_hydro_15 PF00723.16 KZN91444.1 - 4.4e-49 167.2 0.0 6.3e-47 160.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 YfiO PF13525.1 KZN91444.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein F-box-like PF12937.2 KZN91445.1 - 0.0023 17.6 0.9 0.0041 16.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN91445.1 - 0.0075 15.8 0.3 0.026 14.1 0.1 2.1 2 0 0 2 2 2 1 F-box domain Sugar_tr PF00083.19 KZN91446.1 - 6.8e-120 400.6 14.9 9.1e-120 400.2 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91446.1 - 5.6e-29 100.9 27.1 4.9e-23 81.4 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KZN91446.1 - 0.0051 14.9 4.0 0.036 12.1 0.6 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector DUF3611 PF12263.3 KZN91446.1 - 0.22 10.8 0.0 0.22 10.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3611) Pkr1 PF08636.5 KZN91447.1 - 1.3e-32 111.6 6.5 1.7e-32 111.2 4.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KZN91447.1 - 0.007 14.7 0.2 0.0082 14.5 0.1 1.0 1 0 0 1 1 1 1 FHIPEP family Mem_trans PF03547.13 KZN91447.1 - 0.026 12.8 0.0 0.027 12.7 0.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Phage_Gp23 PF10669.4 KZN91447.1 - 0.055 13.5 0.1 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) OAD_gamma PF04277.8 KZN91447.1 - 0.083 13.2 2.8 0.21 11.9 2.0 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cullin PF00888.17 KZN91448.1 - 5.5e-46 157.3 0.3 8.8e-46 156.6 0.2 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KZN91448.1 - 1.9e-21 76.0 0.0 5.9e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 TauD PF02668.11 KZN91449.1 - 5.1e-26 91.9 0.0 6.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATase PF00117.23 KZN91450.1 - 0.0041 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Lactonase PF10282.4 KZN91452.1 - 2.3e-82 276.8 0.0 2.8e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 KZN91452.1 - 0.053 13.5 3.1 0.077 13.0 0.3 2.7 3 0 0 3 3 3 0 Putative Ig domain 3HCDH_N PF02737.13 KZN91453.1 - 1.2e-27 96.7 0.0 3.4e-27 95.2 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN91453.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.12 KZN91453.1 - 0.033 14.5 0.4 14 6.1 0.0 3.5 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B Pyr_redox PF00070.22 KZN91453.1 - 0.037 14.4 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NHL PF01436.16 KZN91453.1 - 0.041 13.8 0.1 1.3 9.1 0.0 3.1 2 0 0 2 2 2 0 NHL repeat DUF3716 PF12511.3 KZN91454.1 - 9.2e-14 50.7 1.8 1.6e-13 50.0 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF987 PF06174.6 KZN91454.1 - 0.074 12.5 0.1 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF987) Macoilin PF09726.4 KZN91454.1 - 1.2 7.3 11.0 0.068 11.4 3.7 1.8 2 0 0 2 2 2 0 Transmembrane protein Pex14_N PF04695.8 KZN91454.1 - 2.9 7.9 12.9 8.1 6.4 6.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Chal_sti_synt_N PF00195.14 KZN91455.1 - 3.5e-18 65.6 0.1 4.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 KZN91455.1 - 0.0039 16.2 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein IU_nuc_hydro PF01156.14 KZN91456.1 - 8.5e-46 156.5 0.0 1.1e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GMC_oxred_N PF00732.14 KZN91457.1 - 4e-54 183.7 0.0 5.3e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91457.1 - 8.5e-31 107.1 0.1 1.6e-30 106.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN91457.1 - 2e-06 26.9 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN91457.1 - 0.00055 18.9 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN91457.1 - 0.00065 19.6 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KZN91457.1 - 0.0063 15.4 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KZN91457.1 - 0.03 14.3 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91457.1 - 0.045 13.6 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN91457.1 - 0.058 11.8 0.0 0.76 8.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KZN91457.1 - 0.07 11.9 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Metallophos PF00149.23 KZN91459.1 - 1.1e-17 64.1 0.0 3.1e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KZN91459.1 - 4.3e-17 61.9 0.0 9.5e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KZN91459.1 - 5.1e-09 35.2 0.1 2.4e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 KZN91459.1 - 0.024 14.4 0.0 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 KZN91459.1 - 0.092 12.8 1.6 0.16 12.0 1.1 1.4 1 0 0 1 1 1 0 Fibronectin type III domain MFS_1 PF07690.11 KZN91460.1 - 2.3e-32 112.0 32.6 3.7e-32 111.4 22.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CMAS PF02353.15 KZN91461.1 - 9e-58 195.5 1.2 1.1e-57 195.1 0.8 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KZN91461.1 - 3e-11 43.2 0.0 5.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN91461.1 - 4.1e-08 33.6 0.0 7.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91461.1 - 5.3e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN91461.1 - 0.0001 22.2 0.0 0.00047 20.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN91461.1 - 0.00012 22.4 0.0 0.00025 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN91461.1 - 0.00022 20.6 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KZN91461.1 - 0.00025 20.6 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KZN91461.1 - 0.0036 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KZN91461.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KZN91461.1 - 0.068 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KZN91461.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FokI_C PF02980.11 KZN91461.1 - 0.11 12.1 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain Aldo_ket_red PF00248.16 KZN91465.1 - 1.6e-41 142.0 0.0 2.3e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.1 KZN91466.1 - 3.8e-37 128.3 0.1 7.6e-24 84.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN91466.1 - 8.5e-26 90.8 1.7 2.6e-24 86.0 0.5 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN91466.1 - 2.3e-06 27.4 0.1 4.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 KR domain Choline_kin_N PF04428.9 KZN91466.1 - 0.011 15.1 0.0 1.7 8.1 0.0 2.5 2 1 0 2 2 2 0 Choline kinase N terminus adh_short PF00106.20 KZN91467.1 - 8.2e-25 87.6 0.7 1.4e-24 86.8 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN91467.1 - 2.7e-19 69.9 0.0 3.3e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN91467.1 - 3.8e-09 36.4 0.6 6.6e-09 35.6 0.4 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 KZN91468.1 - 1.6e-17 63.3 55.8 1.1e-12 47.3 18.0 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91468.1 - 3.2e-05 22.6 13.0 3.2e-05 22.6 9.0 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter QCR10 PF09796.4 KZN91468.1 - 1.4 8.6 6.6 3.5 7.3 0.6 3.3 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) GMC_oxred_C PF05199.8 KZN91469.1 - 2.5e-31 108.9 0.0 3.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KZN91469.1 - 1.5e-27 96.5 0.0 3.9e-23 82.0 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KZN91469.1 - 0.0044 17.0 0.3 0.015 15.2 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN91469.1 - 0.01 15.7 0.0 0.085 12.7 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN91469.1 - 0.015 14.1 0.1 0.031 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 KZN91469.1 - 0.037 12.9 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KZN91469.1 - 0.1 12.0 0.2 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_43 PF04616.9 KZN91470.1 - 5.2e-07 29.0 1.2 1.7e-06 27.3 0.3 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 Asp PF00026.18 KZN91471.1 - 6.4e-38 130.7 5.6 7.8e-38 130.4 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KZN91471.1 - 0.0076 15.8 0.1 0.063 12.8 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KZN91471.1 - 0.019 15.4 0.4 2.3 8.7 0.0 2.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_N PF14543.1 KZN91471.1 - 0.025 14.5 0.3 0.096 12.6 0.1 2.0 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal NAD_binding_4 PF07993.7 KZN91472.1 - 9.8e-40 136.0 0.0 1.4e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN91472.1 - 9.9e-38 129.6 0.0 1.7e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KZN91472.1 - 3.4e-12 46.2 0.0 7.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN91472.1 - 0.00058 20.0 0.0 0.002 18.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PAX PF00292.13 KZN91472.1 - 0.057 13.1 0.0 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 'Paired box' domain adh_short PF00106.20 KZN91472.1 - 0.063 13.1 2.4 0.12 12.3 0.0 2.7 3 1 0 3 3 3 0 short chain dehydrogenase KR PF08659.5 KZN91472.1 - 0.16 11.6 0.8 0.45 10.1 0.0 2.2 2 1 0 2 2 2 0 KR domain GMC_oxred_N PF00732.14 KZN91474.1 - 4.1e-64 216.5 0.0 5.6e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91474.1 - 5.5e-36 124.0 0.1 1.8e-35 122.3 0.0 1.9 3 0 0 3 3 2 1 GMC oxidoreductase DAO PF01266.19 KZN91474.1 - 8.6e-07 28.1 0.1 0.0048 15.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN91474.1 - 3.4e-05 22.8 0.0 0.032 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN91474.1 - 7.2e-05 22.7 0.2 0.00017 21.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN91474.1 - 0.00061 18.8 0.2 0.00095 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KZN91474.1 - 0.0015 18.6 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91474.1 - 0.0021 17.9 0.1 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN91474.1 - 0.13 12.0 0.3 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KZN91474.1 - 0.14 11.2 0.1 0.9 8.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family PsiA PF06952.6 KZN91474.1 - 0.21 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 PsiA protein HI0933_like PF03486.9 KZN91474.1 - 0.27 9.6 0.2 0.64 8.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Mannitol_dh_C PF08125.8 KZN91475.1 - 3.3e-73 245.8 0.0 6.7e-73 244.8 0.0 1.5 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KZN91475.1 - 1e-41 142.3 0.0 2.3e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain PIR PF00399.14 KZN91475.1 - 0.089 12.1 0.3 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Yeast PIR protein repeat Glyco_hydro_72 PF03198.9 KZN91476.1 - 1.4e-132 441.4 5.0 1.8e-132 441.1 3.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KZN91476.1 - 1.6e-20 73.3 1.3 3.9e-20 72.1 0.9 1.7 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KZN91476.1 - 1.6e-05 23.9 0.1 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KZN91476.1 - 0.00055 19.2 0.3 0.0014 17.9 0.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CFC PF09443.5 KZN91476.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Yae1_N PF09811.4 KZN91477.1 - 6.7e-08 31.9 42.0 2.3e+02 1.4 2.0 8.2 3 1 0 3 3 3 0 Essential protein Yae1, N terminal MspA PF09203.6 KZN91477.1 - 0.00089 18.7 0.7 0.31 10.4 0.4 2.4 1 1 0 1 1 1 1 MspA Pkinase PF00069.20 KZN91478.1 - 1.2e-21 76.9 0.0 4.1e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91478.1 - 4.4e-20 71.8 0.0 1e-19 70.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KZN91478.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KZN91478.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_4 PF07993.7 KZN91480.1 - 6e-31 107.2 0.0 8.9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KZN91480.1 - 1.2e-30 106.3 0.0 2.7e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KZN91480.1 - 8.8e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN91480.1 - 8.5e-08 32.3 0.0 4.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN91480.1 - 0.0042 15.8 0.0 0.022 13.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KZN91480.1 - 0.0074 15.2 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 KZN91480.1 - 0.015 14.9 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 KZN91480.1 - 0.024 14.5 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN91480.1 - 0.024 13.5 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KZN91480.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 3 0 0 3 3 3 0 NADH(P)-binding Methyltransf_2 PF00891.13 KZN91481.1 - 1.7e-28 99.4 0.0 3.5e-28 98.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KZN91481.1 - 0.086 12.6 1.1 0.35 10.7 0.7 2.0 1 1 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.1 KZN91481.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BcrAD_BadFG PF01869.15 KZN91482.1 - 4.8e-14 52.2 1.5 9.8e-14 51.2 1.1 1.5 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 KZN91482.1 - 0.002 17.7 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 KZN91482.1 - 0.0058 16.3 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 SIS domain MFS_1 PF07690.11 KZN91483.1 - 1e-15 57.3 37.1 1e-15 57.3 25.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN91483.1 - 2.3e-08 33.7 4.0 2.3e-08 33.7 2.8 3.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 RE_TdeIII PF09520.5 KZN91485.1 - 0.04 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF3433 PF11915.3 KZN91487.1 - 1.9e-45 152.9 20.6 7.4e-25 86.9 1.9 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) ApbA PF02558.11 KZN91488.1 - 1.1e-35 122.3 0.1 1.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KZN91488.1 - 6e-29 100.5 0.0 9.5e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 KZN91488.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KZN91488.1 - 0.03 14.1 0.2 0.083 12.7 0.2 1.8 1 1 0 1 1 1 0 ThiF family Saccharop_dh PF03435.13 KZN91488.1 - 0.097 11.6 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase FMN_dh PF01070.13 KZN91489.1 - 4e-114 381.1 0.0 4.9e-114 380.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KZN91489.1 - 1.9e-18 65.9 0.0 1.3e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KZN91489.1 - 2.4e-06 26.7 0.0 4.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KZN91489.1 - 9.3e-06 24.7 0.4 0.00015 20.8 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KZN91489.1 - 0.012 14.6 0.0 0.025 13.5 0.0 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KZN91489.1 - 0.044 12.8 0.1 7.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KZN91489.1 - 0.083 12.1 0.0 0.99 8.6 0.0 2.3 3 0 0 3 3 3 0 Histidine biosynthesis protein MR_MLE_C PF13378.1 KZN91490.1 - 6.1e-32 109.9 0.0 1e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KZN91490.1 - 1.8e-19 69.8 0.0 3.6e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KZN91490.1 - 5.2e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF1990 PF09348.5 KZN91490.1 - 0.037 13.6 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) MAAL_C PF07476.6 KZN91490.1 - 0.15 10.9 0.0 0.42 9.5 0.0 1.7 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Glyco_hydro_71 PF03659.9 KZN91491.1 - 3.3e-145 483.4 2.6 3.8e-145 483.1 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KZN91491.1 - 0.089 12.5 0.3 0.2 11.3 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) SOBP PF15279.1 KZN91492.1 - 2.9 8.1 16.2 4.2 7.6 11.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CN_hydrolase PF00795.17 KZN91493.1 - 1.8e-34 118.7 0.0 2.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CIA30 PF08547.7 KZN91494.1 - 5.5e-39 133.5 0.0 6.8e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) MFS_1 PF07690.11 KZN91495.1 - 7.7e-40 136.6 44.0 7.7e-40 136.6 30.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91495.1 - 1.3e-09 37.1 14.1 1.3e-09 37.1 9.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_76 PF03663.9 KZN91496.1 - 2e-139 465.0 24.7 2.6e-139 464.7 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Steroid_dh PF02544.11 KZN91496.1 - 0.019 14.7 3.5 1.4 8.7 0.0 3.2 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase COesterase PF00135.23 KZN91497.1 - 1.8e-98 330.5 0.0 2.1e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN91497.1 - 1.3e-07 31.3 0.1 3.1e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN91497.1 - 0.0047 16.6 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN91497.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_2 PF00703.16 KZN91498.1 - 3e-11 43.7 1.6 5.1e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KZN91498.1 - 2.6e-08 33.6 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KZN91498.1 - 0.048 12.5 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_76 PF03663.9 KZN91499.1 - 7e-157 522.5 25.3 8.7e-157 522.2 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KZN91499.1 - 1.3e-05 24.4 8.9 0.17 10.9 0.5 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 ATP-grasp_5 PF13549.1 KZN91499.1 - 0.21 10.7 0.0 0.71 9.0 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ADH_N PF08240.7 KZN91500.1 - 2.1e-26 91.7 0.2 6.5e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN91500.1 - 4.2e-19 68.3 1.7 6.3e-19 67.8 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN91500.1 - 8.4e-05 23.4 0.1 0.00016 22.5 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 KZN91500.1 - 0.033 13.9 0.0 0.17 11.6 0.0 2.3 1 1 1 2 2 2 0 HAD-hyrolase-like Glyco_hydro_1 PF00232.13 KZN91501.1 - 5.2e-75 252.3 0.1 9.6e-73 244.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.20 KZN91502.1 - 1.1e-19 71.0 0.6 1.5e-19 70.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN91502.1 - 3.9e-09 36.4 0.2 4.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN91502.1 - 2.9e-08 33.7 0.0 3.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN91502.1 - 0.00015 21.2 0.3 0.00036 20.0 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 KZN91502.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Med17 PF10156.4 KZN91503.1 - 9.6e-122 406.5 0.2 1.2e-121 406.2 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex DAO PF01266.19 KZN91504.1 - 4.4e-44 150.8 0.2 5.1e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN91504.1 - 2.8e-05 24.0 1.1 5.2e-05 23.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN91504.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KZN91504.1 - 0.022 13.6 0.0 0.042 12.6 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.19 KZN91504.1 - 0.035 13.1 0.3 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KZN91504.1 - 0.044 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KZN91504.1 - 0.068 13.2 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91504.1 - 0.068 13.0 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN91504.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein PFK PF00365.15 KZN91506.1 - 1.2e-163 542.8 1.8 9.5e-118 392.2 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 KZN91506.1 - 0.11 11.2 0.2 0.82 8.3 0.1 2.1 2 0 0 2 2 2 0 ATP-NAD kinase DUF4646 PF15496.1 KZN91506.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) ISN1 PF06437.6 KZN91507.1 - 1.8e-165 550.6 0.0 2e-165 550.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF4646 PF15496.1 KZN91508.1 - 5.1e-14 52.3 0.0 7.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) UBN2_3 PF14244.1 KZN91510.1 - 4e-05 23.2 0.1 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sugar_tr PF00083.19 KZN91511.1 - 6.5e-77 259.0 22.6 8.1e-77 258.6 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91511.1 - 2.1e-14 53.0 53.6 3.3e-12 45.7 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.4 KZN91511.1 - 0.45 10.4 3.6 1 9.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) MFS_1 PF07690.11 KZN91512.1 - 1.2e-30 106.3 30.5 1.7e-30 105.9 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN91513.1 - 3.6e-15 55.5 1.4 4.3e-15 55.2 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91513.1 - 1e-08 34.9 12.0 1.9e-08 34.0 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRXRR PF14239.1 KZN91513.1 - 0.26 10.6 1.7 12 5.3 0.0 2.3 2 0 0 2 2 2 0 RRXRR protein ABC2_membrane PF01061.19 KZN91514.1 - 2.8e-84 281.4 50.7 7.2e-47 159.2 12.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KZN91514.1 - 1.7e-36 125.4 0.0 2.1e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN91514.1 - 3.8e-25 87.5 4.2 6.8e-23 80.2 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KZN91514.1 - 2.1e-09 36.8 33.8 1.3e-07 31.0 11.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KZN91514.1 - 1.7e-08 34.7 0.0 0.084 12.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KZN91514.1 - 8.3e-07 29.1 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KZN91514.1 - 1.1e-05 24.9 0.5 0.008 15.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 KZN91514.1 - 6.1e-05 22.6 0.5 0.035 13.7 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KZN91514.1 - 0.00012 21.3 0.0 0.0025 17.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KZN91514.1 - 0.00018 21.8 0.1 0.059 13.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 KZN91514.1 - 0.00029 20.1 0.0 0.13 11.4 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KZN91514.1 - 0.00033 20.7 0.0 0.092 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN91514.1 - 0.0005 19.5 0.2 0.0063 16.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KZN91514.1 - 0.00057 19.6 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 KZN91514.1 - 0.0042 16.7 0.2 0.27 10.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.1 KZN91514.1 - 0.0053 16.7 0.1 0.036 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KZN91514.1 - 0.0073 17.1 0.3 0.095 13.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KZN91514.1 - 0.0091 15.4 0.1 0.34 10.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KZN91514.1 - 0.011 15.4 0.3 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 KZN91514.1 - 0.015 15.8 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KZN91514.1 - 0.019 14.8 0.0 0.14 12.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN91514.1 - 0.02 14.3 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KZN91514.1 - 0.024 14.1 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KZN91514.1 - 0.08 12.9 0.0 9.8 6.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 KZN91514.1 - 0.12 12.3 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KZN91514.1 - 0.27 10.7 0.1 1.2 8.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KZN91514.1 - 0.31 11.3 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain SurE PF01975.12 KZN91515.1 - 1.1e-30 106.4 0.4 1.5e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Survival protein SurE NPP1 PF05630.6 KZN91516.1 - 2.8e-57 193.7 0.0 3.2e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_61 PF03443.9 KZN91517.1 - 7.6e-79 264.5 0.1 1.4e-78 263.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KZN91517.1 - 3.7e-13 48.8 8.7 9.6e-13 47.5 6.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain MFS_1 PF07690.11 KZN91518.1 - 4.3e-33 114.4 25.2 5.4e-33 114.1 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_25 PF13481.1 KZN91518.1 - 0.0049 16.2 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF1049 PF06305.6 KZN91518.1 - 0.71 9.3 6.0 19 4.8 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Glyco_hydro_88 PF07470.8 KZN91519.1 - 4.5e-90 302.0 2.2 5.8e-90 301.7 1.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KZN91519.1 - 0.0025 16.1 0.1 0.0034 15.7 0.1 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 KZN91519.1 - 0.6 9.4 10.1 3 7.1 0.9 3.1 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 Amidohydro_1 PF01979.15 KZN91520.1 - 1.9e-55 188.8 0.2 2.9e-55 188.2 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KZN91520.1 - 2.5e-12 47.4 0.1 4.5e-09 36.7 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KZN91520.1 - 2.4e-11 43.5 0.0 1.5e-09 37.6 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN91520.1 - 5.2e-08 32.5 0.0 1.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KZN91520.1 - 0.0019 17.2 0.0 0.0057 15.6 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Aldedh PF00171.17 KZN91521.1 - 1.6e-138 461.9 0.0 2e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family P5CR_dimer PF14748.1 KZN91523.1 - 3.3e-36 123.5 1.1 3.3e-36 123.5 0.8 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KZN91523.1 - 8.6e-17 61.3 0.2 2.3e-16 60.0 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KZN91523.1 - 2.4e-05 24.1 2.0 0.00023 20.9 1.4 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KZN91523.1 - 0.019 14.8 0.2 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NMT1_2 PF13379.1 KZN91523.1 - 0.022 14.1 0.1 0.18 11.1 0.0 2.2 3 0 0 3 3 3 0 NMT1-like family Shikimate_DH PF01488.15 KZN91523.1 - 0.052 13.6 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KZN91523.1 - 0.072 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.12 KZN91523.1 - 0.086 11.7 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase CoA_binding_2 PF13380.1 KZN91523.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DUF2296 PF10058.4 KZN91524.1 - 3.3e-18 65.1 0.1 5.7e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) PAT1 PF09770.4 KZN91524.1 - 3.5 5.7 17.0 5.3 5.1 11.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribonuclease_3 PF00636.21 KZN91525.1 - 2.6e-44 150.2 0.0 1.9e-23 83.0 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN91525.1 - 5.1e-29 100.8 0.0 3.3e-14 52.9 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KZN91525.1 - 6e-25 86.8 0.0 2.9e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 KZN91525.1 - 1.1e-14 53.9 0.0 3.4e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN91525.1 - 2.4e-13 49.9 0.0 3.8e-12 46.0 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KZN91525.1 - 2.2e-09 37.4 0.2 2.5e-08 33.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KZN91525.1 - 0.046 12.5 0.2 0.18 10.5 0.1 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain DIOX_N PF14226.1 KZN91527.1 - 1.5e-20 73.8 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN91527.1 - 3.5e-15 56.0 0.0 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fructosamin_kin PF03881.9 KZN91527.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Fungal_trans_2 PF11951.3 KZN91528.1 - 2.5e-49 167.9 4.6 3.3e-49 167.5 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain peroxidase PF00141.18 KZN91529.1 - 1.3e-82 276.7 0.0 2.7e-44 151.3 0.0 2.3 2 0 0 2 2 2 2 Peroxidase FAD_binding_3 PF01494.14 KZN91530.1 - 1.8e-25 89.7 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN91530.1 - 4.3e-08 32.4 0.3 4.2e-06 25.9 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN91530.1 - 3e-06 27.5 0.4 0.00032 21.0 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN91530.1 - 0.00057 19.8 0.2 0.0031 17.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KZN91530.1 - 0.0041 16.5 0.2 0.0074 15.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KZN91530.1 - 0.0051 15.7 2.0 0.0052 15.6 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 KZN91530.1 - 0.0085 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KZN91530.1 - 0.0093 15.6 0.3 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KZN91530.1 - 0.0095 15.0 0.9 0.024 13.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KZN91530.1 - 0.011 14.4 0.4 5.8 5.4 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KZN91530.1 - 0.017 14.9 0.2 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN91530.1 - 0.033 13.0 0.7 0.045 12.6 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 KZN91530.1 - 0.071 11.9 0.0 0.1 11.4 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase TrkA_N PF02254.13 KZN91530.1 - 0.091 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KZN91530.1 - 0.11 11.5 0.3 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KZN91530.1 - 0.13 11.1 0.3 0.29 10.0 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein AphA_like PF14557.1 KZN91530.1 - 0.13 11.7 0.0 0.79 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator NAD_Gly3P_dh_N PF01210.18 KZN91530.1 - 0.15 11.8 0.1 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Apyrase PF06079.6 KZN91532.1 - 0.055 12.6 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 Apyrase MFS_1 PF07690.11 KZN91534.1 - 2.3e-11 42.9 21.4 2.7e-11 42.7 14.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3488 PF11992.3 KZN91534.1 - 6 5.4 8.5 1.3 7.5 3.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3488) M20_dimer PF07687.9 KZN91535.1 - 6.1e-09 35.6 0.0 1.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KZN91535.1 - 1.6e-08 34.2 0.2 2.6e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.14 KZN91537.1 - 1.4e-55 188.5 0.0 1.9e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN91537.1 - 4.4e-32 111.3 0.0 7.3e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN91537.1 - 6.5e-07 28.5 0.3 0.002 17.1 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN91537.1 - 8.1e-05 21.7 0.1 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KZN91537.1 - 0.00046 20.1 0.2 0.0013 18.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN91537.1 - 0.0041 15.6 0.1 0.16 10.4 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KZN91537.1 - 0.0045 15.8 0.2 1.5 7.6 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KZN91537.1 - 0.0097 14.7 1.9 0.031 13.1 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN91537.1 - 0.012 15.4 0.2 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN91537.1 - 0.053 13.5 0.1 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN91537.1 - 0.1 12.3 0.7 0.24 11.1 0.1 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KZN91537.1 - 0.15 12.4 0.2 0.64 10.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN91537.1 - 2.3 7.2 4.7 1.5 7.7 0.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase bZIP_1 PF00170.16 KZN91538.1 - 0.012 15.4 5.1 0.021 14.7 3.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_1 PF00170.16 KZN91539.1 - 5.9e-08 32.5 14.3 1.3e-07 31.4 6.8 2.5 2 1 0 2 2 2 1 bZIP transcription factor Adeno_PIX PF03955.9 KZN91539.1 - 0.02 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) BLOC1_2 PF10046.4 KZN91539.1 - 0.091 12.9 0.7 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glutaredoxin2_C PF04399.8 KZN91539.1 - 0.092 12.3 0.1 0.24 10.9 0.1 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 KZN91539.1 - 0.32 10.8 12.7 4.6 7.1 7.0 2.9 2 1 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 KZN91539.1 - 0.33 11.3 2.0 0.23 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Anoctamin PF04547.7 KZN91540.1 - 1e-123 413.3 3.3 1.4e-123 412.9 2.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Acetyltransf_1 PF00583.19 KZN91540.1 - 1.4e-13 50.6 0.0 3.8e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KZN91540.1 - 2.7e-06 27.0 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KZN91540.1 - 9.7e-06 25.6 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN91540.1 - 0.00096 19.2 0.0 0.0032 17.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN91540.1 - 0.0024 18.0 0.0 0.0064 16.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GRIP PF01465.15 KZN91541.1 - 2.6e-19 68.4 0.3 5.6e-19 67.3 0.2 1.6 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 KZN91541.1 - 4e-09 36.4 158.4 4.1e-05 23.4 17.5 10.6 3 2 5 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KZN91541.1 - 4.4e-08 32.9 155.4 0.0046 16.5 10.5 9.5 3 2 5 8 8 7 5 IncA protein Spc7 PF08317.6 KZN91541.1 - 1.5e-06 27.0 124.1 0.013 14.2 12.1 7.3 2 2 5 7 7 7 6 Spc7 kinetochore protein GAS PF13851.1 KZN91541.1 - 6.5e-06 25.4 131.3 0.01 15.0 9.1 9.5 3 2 6 9 9 8 5 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KZN91541.1 - 3.8e-05 23.0 57.6 0.18 10.9 0.2 6.6 3 2 2 6 6 6 5 Reovirus sigma C capsid protein FliJ PF02050.11 KZN91541.1 - 6.9e-05 22.8 90.3 0.02 14.9 10.3 9.5 4 2 8 12 12 12 4 Flagellar FliJ protein DUF3584 PF12128.3 KZN91541.1 - 7.6e-05 20.2 43.9 7.6e-05 20.2 30.4 5.5 2 2 2 4 4 4 3 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KZN91541.1 - 0.00011 20.8 101.4 0.046 12.1 14.3 5.6 2 2 3 5 5 5 4 AAA domain Fib_alpha PF08702.5 KZN91541.1 - 0.00018 21.6 80.0 0.19 11.8 5.4 8.0 3 2 4 8 8 8 5 Fibrinogen alpha/beta chain family APG6 PF04111.7 KZN91541.1 - 0.0017 17.4 16.5 0.0017 17.4 11.4 8.2 2 2 8 10 10 9 3 Autophagy protein Apg6 EzrA PF06160.7 KZN91541.1 - 0.0021 16.3 6.1 0.0021 16.3 4.2 6.1 2 2 2 4 4 4 1 Septation ring formation regulator, EzrA IFT57 PF10498.4 KZN91541.1 - 0.0042 15.8 10.9 0.0042 15.8 7.6 6.6 3 2 3 6 6 6 3 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.6 KZN91541.1 - 0.0062 15.9 79.0 0.0066 15.8 3.0 9.2 5 3 3 9 9 9 5 Bacillus haemolytic enterotoxin (HBL) DUF869 PF05911.6 KZN91541.1 - 0.0067 14.7 123.7 0.08 11.1 20.1 5.3 1 1 3 5 5 5 3 Plant protein of unknown function (DUF869) WEMBL PF05701.6 KZN91541.1 - 0.044 12.2 151.6 0.13 10.6 26.2 6.2 2 2 3 5 5 5 0 Weak chloroplast movement under blue light DUF4201 PF13870.1 KZN91541.1 - 0.052 12.9 124.9 0.16 11.4 10.8 10.5 3 2 8 11 11 11 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.7 KZN91541.1 - 0.069 13.4 47.6 1.6 9.0 0.2 9.8 5 3 3 8 8 8 0 Nucleopolyhedrovirus P10 protein AAA_27 PF13514.1 KZN91541.1 - 0.18 9.4 121.1 0.27 8.8 20.1 3.4 2 1 1 3 3 3 0 AAA domain ATG16 PF08614.6 KZN91541.1 - 0.36 10.6 140.1 0.36 10.6 7.6 8.9 3 2 6 9 9 8 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 KZN91541.1 - 0.41 9.9 122.2 0.033 13.5 12.8 7.4 3 2 3 7 7 7 0 Mechanosensitive ion channel porin domain Filament PF00038.16 KZN91541.1 - 0.67 9.3 128.8 0.57 9.5 6.7 9.2 2 2 5 7 7 6 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 KZN91541.1 - 0.92 9.2 141.1 0.24 11.1 12.5 10.3 5 2 3 9 9 7 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.1 KZN91541.1 - 7.7 6.8 80.5 0.024 14.9 3.4 10.4 5 3 4 10 10 10 0 Snapin/Pallidin TBPIP PF07106.8 KZN91541.1 - 9.5 5.7 116.7 0.22 11.0 6.0 10.1 3 2 4 9 9 9 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) cNMP_binding PF00027.24 KZN91542.1 - 2.1e-37 126.7 0.1 5.3e-20 71.0 0.0 5.0 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KZN91542.1 - 6.4e-18 65.4 5.4 1.6e-16 60.8 3.7 2.8 1 1 0 1 1 1 1 Patatin-like phospholipase MARVEL PF01284.18 KZN91543.1 - 6e-16 58.5 10.3 7.7e-16 58.2 7.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2615 PF11027.3 KZN91543.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF872 PF05915.7 KZN91543.1 - 0.018 14.8 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF420 PF04238.7 KZN91543.1 - 0.23 11.4 4.3 0.87 9.5 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF420) Actin PF00022.14 KZN91544.1 - 7.1e-55 186.0 0.0 8.2e-30 103.4 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 KZN91545.1 - 4.9e-28 96.8 6.3 5.3e-28 96.7 4.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KZN91545.1 - 0.041 13.8 0.3 0.043 13.7 0.2 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DUF2443 PF10398.4 KZN91545.1 - 0.091 12.5 0.5 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) DASH_Dad1 PF08649.5 KZN91545.1 - 0.21 11.2 2.3 0.27 10.9 1.6 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.6 KZN91546.1 - 8.4e-16 57.2 0.3 2.3e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 KZN91547.1 - 3.6e-19 68.9 12.8 4.4e-19 68.7 8.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KZN91547.1 - 3.7 7.2 9.1 0.61 9.7 3.4 1.9 2 0 0 2 2 2 0 YrhK-like protein SdpI PF13630.1 KZN91547.1 - 4.9 6.9 12.7 0.74 9.5 2.2 2.3 1 1 1 2 2 2 0 SdpI/YhfL protein family Profilin PF00235.14 KZN91548.1 - 2.4e-35 121.2 0.1 2.7e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.11 KZN91550.1 - 2.2e-144 480.4 0.0 5.9e-96 321.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KZN91550.1 - 5.6e-55 185.4 0.2 5.4e-29 100.8 0.4 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN91550.1 - 1.6e-18 66.3 0.0 8.1e-08 32.0 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KZN91550.1 - 7.1e-17 61.8 0.0 2.3e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KZN91550.1 - 4.3e-09 36.5 0.0 0.0023 18.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KZN91550.1 - 1.4e-05 24.7 0.1 0.016 14.9 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 KZN91550.1 - 4e-05 22.5 0.7 0.046 12.5 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 KZN91550.1 - 0.0043 16.4 0.3 2 7.8 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 KZN91550.1 - 0.01 15.0 0.0 4.4 6.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 KZN91550.1 - 0.015 14.7 0.0 3.6 7.0 0.1 3.3 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KZN91550.1 - 0.045 13.1 0.0 8.8 5.6 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain Synaptobrevin PF00957.16 KZN91551.1 - 5.8e-15 54.6 0.7 9.9e-15 53.9 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KZN91551.1 - 6.4e-14 51.2 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tbf5 PF06331.7 KZN91551.1 - 0.0088 15.8 0.7 0.017 14.9 0.5 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Peptidase_S15 PF02129.13 KZN91552.1 - 1.5e-42 145.8 1.1 2.1e-42 145.4 0.8 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KZN91552.1 - 3.7e-37 128.3 0.1 6.2e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KZN91552.1 - 2.2e-06 27.7 0.8 3.7e-06 27.0 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN91552.1 - 1.8e-05 24.5 0.2 4.3e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN91552.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DIPSY PF11763.3 KZN91552.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal FAD_binding_3 PF01494.14 KZN91553.1 - 1.3e-23 83.6 0.1 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.6 KZN91553.1 - 4.8e-09 35.9 0.0 1.4e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.1 KZN91553.1 - 1.6e-07 31.2 0.2 4.4e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN91553.1 - 2.4e-05 24.4 0.1 4.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN91553.1 - 8e-05 21.7 1.9 0.00011 21.2 0.4 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN91553.1 - 0.0001 21.3 0.7 0.0001 21.3 0.5 1.9 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN91553.1 - 0.00011 22.1 0.1 0.0002 21.3 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KZN91553.1 - 0.0057 15.3 0.6 0.0097 14.5 0.2 1.4 1 1 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 KZN91553.1 - 0.012 14.6 0.3 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KZN91553.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN91553.1 - 0.029 13.2 0.2 0.043 12.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KZN91553.1 - 0.048 13.4 0.7 0.11 12.2 0.5 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KZN91553.1 - 0.049 12.1 0.1 0.087 11.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KZN91553.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KZN91553.1 - 0.12 11.2 0.8 4.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein zf-C2H2 PF00096.21 KZN91554.1 - 9.1e-11 41.4 10.0 1.6e-05 24.9 0.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN91554.1 - 1.5e-08 34.3 8.3 0.00094 19.3 0.4 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN91554.1 - 1.7e-06 27.9 11.7 4.5e-06 26.6 3.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain Zn_clus PF00172.13 KZN91554.1 - 3.7e-05 23.5 12.3 3.7e-05 23.5 8.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 KZN91554.1 - 0.048 13.8 4.7 2.4 8.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Cupin_2 PF07883.6 KZN91555.1 - 1.2e-09 37.4 0.0 2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KZN91555.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 KZN91555.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin FAA_hydrolase PF01557.13 KZN91556.1 - 5.5e-52 176.3 0.0 7e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KZN91556.1 - 1.4e-15 57.1 0.0 3.6e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.11 KZN91557.1 - 2.7e-40 138.1 19.7 2.7e-40 138.1 13.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91557.1 - 4.7e-13 48.5 19.0 8.3e-13 47.7 13.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KZN91557.1 - 1.7e-07 29.8 4.8 2.8e-07 29.1 3.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KZN91557.1 - 0.00073 17.7 1.0 0.0018 16.3 0.7 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3169 PF11368.3 KZN91557.1 - 0.026 13.7 7.9 0.11 11.6 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF3353 PF11833.3 KZN91557.1 - 1.3 8.4 9.1 6.7 6.1 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) LigB PF02900.13 KZN91558.1 - 3.2e-24 85.3 0.2 3.9e-24 85.0 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FeoB_C PF07664.7 KZN91559.1 - 0.046 13.1 0.2 0.095 12.1 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Aldedh PF00171.17 KZN91560.1 - 8.1e-16 57.4 0.1 1.9e-09 36.3 0.0 2.7 3 0 0 3 3 3 2 Aldehyde dehydrogenase family Cupin_2 PF07883.6 KZN91562.1 - 1e-07 31.3 0.1 1.4e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 KZN91562.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 Cysteine dioxygenase type I Sugar_tr PF00083.19 KZN91563.1 - 9.7e-50 169.4 27.3 1.1e-49 169.3 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91563.1 - 1.3e-16 60.2 38.8 1.6e-16 59.9 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.3 KZN91563.1 - 0.12 11.8 0.3 0.12 11.8 0.2 2.7 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Cation_efflux PF01545.16 KZN91564.1 - 0.022 13.8 4.2 0.025 13.6 0.1 2.2 2 1 0 2 2 2 0 Cation efflux family Dpy19 PF10034.4 KZN91565.1 - 0.0021 16.3 0.0 0.0023 16.1 0.0 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation OPA3 PF07047.7 KZN91565.1 - 0.0037 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Bim_N PF06773.6 KZN91565.1 - 0.014 15.1 0.9 0.023 14.4 0.6 1.3 1 0 0 1 1 1 0 Bim protein N-terminus DUF4133 PF13571.1 KZN91565.1 - 7.3 6.8 8.0 0.91 9.7 0.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4133) FAD_binding_4 PF01565.18 KZN91566.1 - 1.3e-22 79.7 0.0 2.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN91566.1 - 5e-05 23.1 2.5 5.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Berberine and berberine like SSF PF00474.12 KZN91567.1 - 1.7e-25 89.5 31.6 2.4e-25 89.0 21.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family WTF PF03303.8 KZN91567.1 - 0.0088 15.4 0.1 0.022 14.1 0.1 1.7 1 0 0 1 1 1 1 WTF protein ADH_N PF08240.7 KZN91568.1 - 1.2e-06 28.1 0.1 4.6e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3431 PF11913.3 KZN91569.1 - 5.8e-85 284.2 0.0 7.2e-85 283.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.17 KZN91571.1 - 2e-16 59.7 0.0 5.5e-09 35.6 0.0 3.0 2 1 1 3 3 3 2 Ras family Miro PF08477.8 KZN91571.1 - 2.5e-06 27.9 0.1 2.4e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KZN91571.1 - 0.0022 18.0 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN91571.1 - 0.036 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KZN91571.1 - 0.051 13.5 0.4 0.17 11.8 0.1 2.0 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 KZN91571.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KZN91571.1 - 0.08 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KZN91571.1 - 0.088 12.6 0.1 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KZN91571.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA PF00004.24 KZN91571.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KZN91571.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KZN91571.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 KZN91571.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Sugar_tr PF00083.19 KZN91572.1 - 1.6e-99 333.5 27.7 1.9e-99 333.3 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91572.1 - 1e-24 86.9 38.5 2.1e-14 53.0 8.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 KZN91572.1 - 0.073 13.0 0.0 0.073 13.0 0.0 3.4 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF1228 PF06779.9 KZN91572.1 - 3.5 7.7 8.4 0.65 10.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) FMN_dh PF01070.13 KZN91573.1 - 1.6e-122 408.7 0.1 2.1e-122 408.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KZN91573.1 - 1.6e-24 85.4 0.0 3.8e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KZN91573.1 - 8.4e-07 28.2 0.1 1.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KZN91573.1 - 0.00031 20.0 0.4 0.00056 19.1 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KZN91573.1 - 0.00092 18.1 0.1 0.003 16.5 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KZN91573.1 - 0.058 12.6 1.6 1.2 8.3 0.0 2.5 2 1 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 KZN91573.1 - 0.069 12.2 0.0 6.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 KZN91573.1 - 0.078 11.9 0.1 1.9 7.3 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) Metallophos PF00149.23 KZN91574.1 - 2.7e-06 26.9 5.3 0.00047 19.6 0.7 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN91574.1 - 0.0001 22.1 0.1 0.00025 20.9 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4589 PF15252.1 KZN91574.1 - 0.075 12.8 0.7 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Pkinase PF00069.20 KZN91575.1 - 4.4e-42 144.0 0.5 1.1e-24 86.9 0.2 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91575.1 - 3.4e-15 55.8 0.5 8.7e-11 41.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DNA_binding_1 PF01035.15 KZN91576.1 - 4.4e-21 74.4 0.1 6.4e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Bud13 PF09736.4 KZN91577.1 - 2.5e-46 157.5 7.1 2.5e-46 157.5 4.9 3.0 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF4551 PF15087.1 KZN91577.1 - 0.033 12.5 3.1 0.048 12.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hom_end_hint PF05203.11 KZN91577.1 - 0.12 12.1 0.9 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint SPATIAL PF15256.1 KZN91577.1 - 0.44 10.5 3.8 0.86 9.6 2.7 1.5 1 0 0 1 1 1 0 SPATIAL FAM74 PF15026.1 KZN91577.1 - 1 9.0 6.8 2 8.0 4.7 1.5 1 0 0 1 1 1 0 FAM74 protein Brr6_like_C_C PF10104.4 KZN91578.1 - 6.4e-42 142.2 0.7 8.5e-42 141.8 0.5 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.11 KZN91579.1 - 3.3e-31 108.2 47.2 3.3e-31 108.2 32.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91579.1 - 1.2e-09 37.2 39.1 4.3e-08 32.1 9.5 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KZN91579.1 - 5.1e-07 28.4 7.3 5.1e-07 28.4 5.1 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein Glyco_transf_20 PF00982.16 KZN91580.1 - 9.2e-156 519.0 0.0 1.1e-155 518.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KZN91580.1 - 0.0034 16.8 0.3 0.082 12.3 0.2 2.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 DUF693 PF05113.8 KZN91580.1 - 0.0042 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF693) Glyco_trans_1_2 PF13524.1 KZN91580.1 - 0.0062 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KZN91580.1 - 0.0098 16.0 0.0 0.035 14.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KZN91580.1 - 0.14 11.5 0.2 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain AA_permease PF00324.16 KZN91581.1 - 1.1e-130 436.2 41.3 1.3e-130 435.9 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN91581.1 - 2.1e-36 125.3 45.6 2.6e-36 125.1 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease PMBR PF09373.5 KZN91581.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Ribonuclease PF00545.15 KZN91582.1 - 1e-19 70.3 0.2 1.3e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 ribonuclease YjbE PF11106.3 KZN91582.1 - 0.052 13.5 3.5 0.091 12.7 2.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE GST_N_3 PF13417.1 KZN91583.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN91583.1 - 1.8e-09 37.4 0.2 2.8e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KZN91583.1 - 2.7e-09 37.0 0.0 7.4e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN91583.1 - 8.3e-09 35.3 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN91583.1 - 0.00023 21.5 0.1 0.00035 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN91583.1 - 0.00029 20.6 0.0 0.00044 20.0 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KZN91583.1 - 0.025 14.9 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 MetRS-N binding domain Methyltransf_31 PF13847.1 KZN91584.1 - 4.9e-28 97.6 0.0 6.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN91584.1 - 6e-26 90.7 0.0 1e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN91584.1 - 2.5e-20 72.6 0.0 3.6e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KZN91584.1 - 3.6e-16 59.3 0.0 4.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN91584.1 - 6.1e-16 58.7 0.0 1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91584.1 - 4.1e-15 56.3 0.0 6.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN91584.1 - 3.5e-14 53.0 0.0 5.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN91584.1 - 6.2e-10 39.1 0.1 1.3e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN91584.1 - 9.9e-09 34.7 0.0 1.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KZN91584.1 - 1.7e-08 34.0 0.0 2.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KZN91584.1 - 3.5e-06 26.7 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 KZN91584.1 - 0.00039 19.2 0.0 0.0006 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 KZN91584.1 - 0.00058 19.3 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 KZN91584.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 KZN91584.1 - 0.004 16.0 0.0 0.0088 14.9 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 KZN91584.1 - 0.0064 15.6 0.0 0.0081 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 KZN91584.1 - 0.0064 14.8 0.0 0.0084 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 KZN91584.1 - 0.0073 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KZN91584.1 - 0.023 14.3 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase RrnaAD PF00398.15 KZN91584.1 - 0.024 13.6 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 KZN91584.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.14 KZN91584.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 KZN91584.1 - 0.07 13.9 0.1 0.37 11.6 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 KZN91584.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 KZN91584.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WW PF00397.21 KZN91585.1 - 1.1e-06 28.3 0.4 3.4e-06 26.8 0.3 1.9 1 0 0 1 1 1 1 WW domain Gly-zipper_OmpA PF13436.1 KZN91585.1 - 0.035 13.7 0.6 0.056 13.0 0.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF2076 PF09849.4 KZN91585.1 - 0.064 13.3 7.6 0.078 13.0 5.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Na_Ca_ex PF01699.19 KZN91586.1 - 2.5e-40 137.3 33.0 1.7e-21 76.2 9.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CorA PF01544.13 KZN91587.1 - 1.1e-38 133.0 0.0 1.3e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Anoctamin PF04547.7 KZN91588.1 - 1.2e-78 264.8 0.0 1.6e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel YbgT_YccB PF08173.6 KZN91589.1 - 3.4 7.5 6.3 0.38 10.5 1.1 1.9 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Transp_cyt_pur PF02133.10 KZN91590.1 - 2.9e-84 283.1 42.9 3.3e-84 282.9 29.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TauD PF02668.11 KZN91591.1 - 1.3e-21 77.4 0.0 1.7e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KZN91591.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 CsiD PEP_mutase PF13714.1 KZN91592.1 - 3.3e-30 105.0 0.0 3.6e-19 68.9 0.0 2.0 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KZN91592.1 - 3.1e-12 45.5 0.1 4.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Fungal_trans PF04082.13 KZN91593.1 - 7e-23 80.8 1.0 1.3e-22 79.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91593.1 - 4.7e-09 35.9 10.5 8.8e-09 35.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 KZN91594.1 - 9.9e-09 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.16 KZN91595.1 - 2.4e-88 296.9 0.7 3.1e-88 296.5 0.5 1.1 1 0 0 1 1 1 1 Amidase DUF1212 PF06738.7 KZN91596.1 - 4.2e-52 176.4 12.2 2.8e-47 160.6 0.6 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KZN91596.1 - 1.6e-28 99.1 8.2 1.6e-28 99.1 5.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) Pectate_lyase_3 PF12708.2 KZN91597.1 - 5.6e-52 177.1 15.9 1.4e-38 133.3 3.7 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.1 KZN91597.1 - 0.003 17.3 6.8 0.003 17.3 4.7 2.1 2 0 0 2 2 2 1 Right handed beta helix region End_N_terminal PF12218.3 KZN91597.1 - 0.011 15.1 1.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF566 PF04484.7 KZN91597.1 - 3.2 7.1 8.5 4.8 6.6 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Raptor_N PF14538.1 KZN91599.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain MIP PF00230.15 KZN91600.1 - 1.3e-45 155.6 8.7 1.7e-45 155.2 6.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.16 KZN91601.1 - 7.4e-12 45.8 0.0 1.3e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 KZN91601.1 - 3e-08 33.9 0.0 9.5e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 KZN91601.1 - 3e-08 33.6 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KZN91601.1 - 1.6e-05 24.8 0.0 8e-05 22.5 0.0 2.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 KZN91601.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protoglobin Guanylate_kin PF00625.16 KZN91601.1 - 0.032 13.6 0.1 0.071 12.5 0.0 1.6 1 1 1 2 2 2 0 Guanylate kinase Dabb PF07876.7 KZN91601.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain NmrA PF05368.8 KZN91602.1 - 2.2e-19 69.6 0.0 2.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN91602.1 - 9.3e-11 42.0 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN91602.1 - 0.0043 15.7 0.0 0.0082 14.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KZN91602.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PhageMin_Tail PF10145.4 KZN91602.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein adh_short PF00106.20 KZN91602.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase HLH PF00010.21 KZN91604.1 - 1.8e-10 40.3 0.1 3.6e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AA_permease_2 PF13520.1 KZN91605.1 - 2.3e-58 197.7 50.7 2.8e-58 197.4 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN91605.1 - 9.8e-23 80.2 41.3 1.3e-22 79.8 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4235 PF14019.1 KZN91605.1 - 0.035 13.9 0.4 0.093 12.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF3493 PF11998.3 KZN91605.1 - 0.15 12.0 2.8 0.2 11.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Pro-kuma_activ PF09286.6 KZN91606.1 - 4.4e-36 124.0 0.1 2.1e-35 121.8 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KZN91606.1 - 6.9e-15 54.9 1.4 1e-14 54.3 0.1 1.8 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 KZN91607.1 - 6.2e-08 32.7 0.1 1.1e-07 31.9 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN91607.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Alpha_GJ PF03229.8 KZN91608.1 - 0.018 15.3 16.2 0.12 12.7 5.4 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF3447 PF11929.3 KZN91608.1 - 0.11 12.3 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Sugar_tr PF00083.19 KZN91609.1 - 3.1e-110 368.8 27.4 4.2e-110 368.4 19.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91609.1 - 5.6e-28 97.6 40.3 8e-20 70.8 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KZN91610.1 - 1.5e-24 86.5 0.0 2.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91610.1 - 5.7e-07 28.8 0.5 9.7e-06 24.8 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KZN91610.1 - 0.0038 16.6 0.1 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Acetyltransf_1 PF00583.19 KZN91611.1 - 0.00022 21.1 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN91611.1 - 0.0022 18.1 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ImpA-rel_N PF06812.7 KZN91611.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 ImpA-related N-terminal Sugar_tr PF00083.19 KZN91612.1 - 1.5e-35 122.6 23.5 6.4e-26 90.9 5.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KZN91612.1 - 3.7e-29 101.5 23.3 3.7e-29 101.5 16.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3533 PF12051.3 KZN91613.1 - 2.3e-125 418.3 10.8 2.6e-125 418.1 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF202 PF02656.10 KZN91613.1 - 0.05 13.8 0.0 0.05 13.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) PQ-loop PF04193.9 KZN91614.1 - 7.6e-08 31.7 0.8 0.00062 19.2 0.1 3.2 2 0 0 2 2 2 2 PQ loop repeat UvrD_C_2 PF13538.1 KZN91614.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain BCLP PF12304.3 KZN91614.1 - 0.2 11.0 3.9 0.41 10.0 2.7 1.6 1 1 0 1 1 1 0 Beta-casein like protein ECH PF00378.15 KZN91615.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DnaJ PF00226.26 KZN91616.1 - 5.6e-18 64.4 0.7 5.6e-18 64.4 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain IncA PF04156.9 KZN91616.1 - 3.3 7.2 9.0 6.7 6.2 6.2 1.5 1 0 0 1 1 1 0 IncA protein Complex1_LYR PF05347.10 KZN91617.1 - 2.1e-05 24.2 0.2 3.7e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN91617.1 - 0.00041 20.4 0.1 0.00079 19.5 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 KZN91618.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN91618.1 - 5.5e-08 32.3 0.0 9.3e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN91618.1 - 0.00069 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN91618.1 - 0.0041 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 KZN91619.1 - 1.2e-26 92.4 0.0 2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KZN91619.1 - 3.4e-22 78.7 0.0 6.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN91619.1 - 1.4e-17 63.7 0.0 2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN91619.1 - 3.6e-14 52.7 0.0 6.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN91619.1 - 8.2e-14 51.7 0.0 1.5e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN91619.1 - 3.3e-11 43.7 0.0 7.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KZN91619.1 - 1.1e-10 41.0 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KZN91619.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KZN91619.1 - 1e-09 38.7 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN91619.1 - 3.7e-09 36.6 0.0 1.2e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KZN91619.1 - 3.2e-05 23.5 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KZN91619.1 - 8.1e-05 21.8 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KZN91619.1 - 0.00033 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 KZN91619.1 - 0.00049 19.2 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.11 KZN91619.1 - 0.00055 18.4 0.0 0.00069 18.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 KZN91619.1 - 0.001 18.6 0.1 0.0022 17.5 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KZN91619.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KZN91619.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KZN91619.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ank_2 PF12796.2 KZN91620.1 - 6.9e-58 192.9 1.8 7.7e-14 51.8 0.0 6.9 4 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN91620.1 - 1.9e-41 137.8 16.2 0.00016 21.2 0.0 12.2 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.1 KZN91620.1 - 6.9e-37 121.8 3.7 0.00024 21.0 0.0 12.6 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 KZN91620.1 - 7.5e-29 99.5 11.4 0.00019 21.8 0.1 10.8 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN91620.1 - 2.7e-26 90.9 12.2 4.2e-05 23.6 0.0 11.6 8 3 5 13 13 13 7 Ankyrin repeats (many copies) Phosphoesterase PF04185.9 KZN91621.1 - 1.6e-33 116.4 1.3 7.7e-33 114.2 0.9 1.8 1 1 0 1 1 1 1 Phosphoesterase family Sugar_tr PF00083.19 KZN91622.1 - 4.6e-111 371.5 27.9 5.5e-111 371.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91622.1 - 1e-17 63.9 39.3 4.5e-11 42.0 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KZN91623.1 - 1.4e-44 152.3 23.1 1.4e-44 152.3 16.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91623.1 - 3.3e-19 68.7 11.5 4.9e-19 68.2 8.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KZN91623.1 - 1.6e-06 26.6 1.4 2.7e-06 25.8 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KZN91623.1 - 0.0098 13.9 0.5 0.15 10.1 0.3 2.5 2 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Imm42 PF15601.1 KZN91623.1 - 0.2 11.0 0.3 0.36 10.2 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 42 MFS_3 PF05977.8 KZN91623.1 - 0.69 7.9 4.7 1.1 7.2 3.3 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Fungal_trans_2 PF11951.3 KZN91624.1 - 3.3e-41 141.1 0.9 4.2e-41 140.8 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91624.1 - 2.5e-07 30.5 10.1 4.5e-07 29.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KZN91625.1 - 3.6e-26 92.0 1.2 5.1e-26 91.5 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN91625.1 - 1.5e-15 57.6 0.0 1.9e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN91625.1 - 3.3e-09 36.6 0.9 4.7e-09 36.1 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KZN91625.1 - 0.00061 19.4 0.2 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KZN91625.1 - 0.0014 18.0 0.2 0.0029 17.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KZN91625.1 - 0.0025 16.8 0.6 0.0064 15.5 0.4 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KZN91625.1 - 0.0035 17.3 1.1 0.036 14.0 0.7 2.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KZN91625.1 - 0.021 13.8 0.2 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KZN91625.1 - 0.065 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pellino PF04710.9 KZN91625.1 - 0.076 11.6 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Pellino Aldedh PF00171.17 KZN91626.1 - 3.2e-133 444.4 0.0 3.6e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN91626.1 - 6.3e-05 21.8 0.2 0.00021 20.1 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KZN91626.1 - 0.00097 18.4 0.4 0.0029 16.8 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GATase PF00117.23 KZN91627.1 - 2.1e-08 33.8 0.0 2.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN91627.1 - 2.3e-05 23.9 0.0 0.00012 21.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 KZN91627.1 - 4.3e-05 23.1 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 KZN91627.1 - 0.0069 15.6 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase RusA PF05866.6 KZN91627.1 - 0.035 14.5 0.1 0.051 13.9 0.1 1.2 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA SNO PF01174.14 KZN91627.1 - 0.05 13.2 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Gln-synt_C PF00120.19 KZN91628.1 - 1.9e-56 191.1 0.0 2.4e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Cation_efflux PF01545.16 KZN91629.1 - 5.5e-32 110.9 6.8 7.1e-32 110.6 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family Cyclase PF04199.8 KZN91631.1 - 6.6e-07 29.1 0.0 9.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KZN91631.1 - 0.054 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RHD3 PF05879.7 KZN91632.1 - 0 1055.4 0.0 0 1055.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KZN91632.1 - 3.4e-07 29.5 0.1 5.6e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KZN91632.1 - 1.5e-06 28.1 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 KZN91632.1 - 0.00087 19.2 0.0 0.0027 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KZN91632.1 - 0.00091 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN91632.1 - 0.0018 18.7 0.0 0.0038 17.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Fungal_trans PF04082.13 KZN91633.1 - 1.4e-06 27.4 0.1 2.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91633.1 - 3.1e-06 27.0 12.8 7.8e-06 25.7 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 KZN91635.1 - 2.2e-60 203.3 0.1 3.1e-60 202.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KZN91635.1 - 5.8e-22 77.7 0.0 1.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KZN91635.1 - 1.4e-17 63.5 3.0 1.5e-17 63.4 1.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN91635.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KZN91635.1 - 0.0026 17.3 0.1 0.0072 15.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KZN91635.1 - 0.0056 17.1 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KZN91635.1 - 0.066 12.6 0.1 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GDA1_CD39 PF01150.12 KZN91636.1 - 2.9e-95 319.3 0.0 4.1e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.1 KZN91637.1 - 4.6e-43 146.0 5.9 4.6e-43 146.0 4.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Macoilin PF09726.4 KZN91637.1 - 0.47 8.6 7.1 0.63 8.2 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 KZN91637.1 - 1.5 8.2 14.8 0.095 12.1 6.7 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 KZN91637.1 - 2.5 7.7 18.6 4.1 7.0 1.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 KZN91637.1 - 6.6 6.3 10.9 3.9 7.1 3.6 2.2 2 0 0 2 2 2 0 FAM176 family Nop25 PF09805.4 KZN91637.1 - 8.1 6.5 11.3 8.4 6.4 2.0 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) COMPASS-Shg1 PF05205.7 KZN91638.1 - 3.2e-31 107.7 0.1 9e-31 106.3 0.1 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 zf-RING_2 PF13639.1 KZN91640.1 - 1.6e-10 40.6 3.9 4.9e-09 35.8 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KZN91640.1 - 3.3e-09 36.7 0.3 6.3e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN91640.1 - 1.2e-06 28.0 0.9 2.1e-06 27.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN91640.1 - 1.9e-06 27.4 2.4 6.3e-06 25.8 1.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KZN91640.1 - 1.4e-05 24.6 5.7 6.6e-05 22.4 4.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN91640.1 - 0.00013 21.8 2.4 0.00013 21.8 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN91640.1 - 0.0081 15.9 1.1 0.019 14.8 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 KZN91640.1 - 0.18 9.4 0.5 0.33 8.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 KZN91640.1 - 0.41 10.4 3.7 0.46 10.2 0.7 2.5 1 1 1 2 2 2 0 RING-type zinc-finger PQ-loop PF04193.9 KZN91640.1 - 3.1 7.3 10.8 0.44 10.1 0.2 3.0 3 0 0 3 3 3 0 PQ loop repeat FANCL_C PF11793.3 KZN91640.1 - 4.4 7.3 6.0 3.3 7.7 2.1 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain GCV_H PF01597.14 KZN91641.1 - 3.3e-36 123.6 1.8 4.3e-36 123.2 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KZN91641.1 - 0.13 11.8 0.8 1.3 8.6 0.4 2.2 1 1 1 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.12 KZN91642.1 - 1.9e-07 30.8 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 4HBT_3 PF13622.1 KZN91643.1 - 2.4e-43 148.7 0.1 2.9e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4082 PF13313.1 KZN91643.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) DUF2370 PF10176.4 KZN91644.1 - 0.062 12.6 1.4 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2956 PF11169.3 KZN91644.1 - 2.7 7.9 4.8 3.6 7.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRM_1 PF00076.17 KZN91645.1 - 2e-61 203.5 0.0 5.2e-21 74.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN91645.1 - 2e-45 152.5 0.0 1.3e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN91645.1 - 6.6e-30 102.7 0.0 3.5e-10 39.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN91645.1 - 8.3e-05 22.2 0.0 0.023 14.4 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KZN91645.1 - 0.014 15.3 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Glyco_hydro_114 PF03537.8 KZN91645.1 - 0.016 14.9 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Arrestin_C PF02752.17 KZN91647.1 - 9.6e-22 77.5 0.8 5.7e-21 75.0 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KZN91647.1 - 6.9e-07 29.1 0.0 0.00072 19.4 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KZN91647.1 - 0.0099 15.3 0.0 0.056 12.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Acetyltransf_1 PF00583.19 KZN91648.1 - 1.7e-08 34.3 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN91648.1 - 1.4e-07 31.6 0.1 3.2e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN91648.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN91648.1 - 8.8e-05 22.3 0.2 0.011 15.6 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN91648.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KZN91648.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 KZN91648.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Chs3p PF12271.3 KZN91649.1 - 6e-139 462.0 14.3 6.8e-139 461.8 9.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KZN91649.1 - 0.62 9.9 7.3 0.065 13.1 1.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Abhydrolase_5 PF12695.2 KZN91650.1 - 6.3e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN91650.1 - 2.9e-05 24.0 1.0 6.1e-05 23.0 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KZN91650.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KZN91650.1 - 0.00018 21.2 0.2 0.00034 20.2 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 KZN91650.1 - 0.035 13.0 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GATase_4 PF13230.1 KZN91651.1 - 6.9e-14 51.1 0.0 1.3e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KZN91651.1 - 8.1e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KZN91651.1 - 5.4e-06 25.3 0.0 0.00082 18.1 0.0 2.4 3 0 0 3 3 3 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 KZN91652.1 - 2.2e-44 151.2 0.0 3.9e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KZN91652.1 - 1.3e-11 43.8 0.0 2.3e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KZN91652.1 - 0.00089 19.1 0.0 0.0042 17.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN91652.1 - 0.0041 17.6 0.0 0.0085 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KZN91652.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 KZN91653.1 - 3e-25 89.3 0.0 1.2e-14 54.7 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN91653.1 - 1.2e-11 44.8 0.0 7.9e-11 42.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN91653.1 - 0.0013 18.8 0.2 1.5 8.8 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4391 PF14335.1 KZN91653.1 - 0.036 13.4 0.8 0.062 12.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Cyclin PF08613.6 KZN91654.1 - 2.1e-17 63.8 0.1 3.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN91654.1 - 0.00013 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 KZN91655.1 - 6.2e-15 55.7 0.3 6.2e-15 55.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 KZN91656.1 - 1.3e-49 168.6 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91656.1 - 8.5e-27 93.8 0.0 6.3e-26 90.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 KZN91657.1 - 8.6e-07 28.2 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN91657.1 - 0.00037 20.0 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rick_17kDa_Anti PF05433.10 KZN91658.1 - 1.3e-05 24.7 3.5 2e-05 24.1 2.4 1.2 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 KZN91658.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KZN91658.1 - 0.012 15.1 0.9 0.026 14.1 0.6 1.5 1 0 0 1 1 1 0 Glycine zipper DUF533 PF04391.7 KZN91658.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TraT PF05818.7 KZN91658.1 - 0.15 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Innate_immun PF12782.2 KZN91658.1 - 1.8 7.6 30.8 2.9 7.0 21.4 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PAT1 PF09770.4 KZN91658.1 - 2.7 6.1 15.3 3.9 5.5 10.6 1.2 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HTH_Tnp_Tc5 PF03221.11 KZN91659.1 - 2.7e-07 30.2 0.0 6.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BLOC1_2 PF10046.4 KZN91659.1 - 0.016 15.3 0.6 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HTH_psq PF05225.11 KZN91659.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain APH PF01636.18 KZN91660.1 - 2.3e-11 43.9 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KZN91660.1 - 3.4e-08 33.0 0.1 7.7e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KZN91660.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN91660.1 - 0.024 13.2 0.1 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Aegerolysin PF06355.8 KZN91661.1 - 8.2e-39 132.4 0.3 1e-38 132.1 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin HMG-CoA_red PF00368.13 KZN91664.1 - 8.7e-61 205.6 7.2 2.8e-28 98.6 0.0 3.0 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A reductase CBM_4_9 PF02018.12 KZN91665.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain Cyclin PF08613.6 KZN91666.1 - 1.4e-15 58.0 0.1 1.9e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN91666.1 - 0.00059 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TT_ORF2 PF02957.10 KZN91666.1 - 0.8 10.4 8.3 0.16 12.7 1.2 2.7 3 0 0 3 3 3 0 TT viral ORF2 His_Phos_1 PF00300.17 KZN91667.1 - 1.5e-32 112.9 1.1 2.2e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Dor1 PF04124.7 KZN91668.1 - 4.2e-57 193.1 0.9 5.5e-46 156.5 1.9 2.4 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 KZN91668.1 - 0.00011 21.9 0.4 0.00033 20.4 0.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 ApoLp-III PF07464.6 KZN91668.1 - 0.032 14.2 0.3 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Acetyltransf_3 PF13302.1 KZN91669.1 - 2.1e-10 40.9 0.0 1e-09 38.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN91669.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pkinase PF00069.20 KZN91670.1 - 4.8e-15 55.4 0.0 1.1e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN91670.1 - 2.8e-06 27.2 0.0 4.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN91670.1 - 3.7e-06 26.1 0.0 5.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KZN91670.1 - 7e-06 25.2 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KZN91670.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KZN91670.1 - 0.0033 16.7 0.1 0.0075 15.6 0.0 1.6 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 KZN91670.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PhoD PF09423.5 KZN91671.1 - 1e-148 495.6 1.1 1.2e-148 495.4 0.7 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase DUF4237 PF14021.1 KZN91672.1 - 5.8e-31 106.6 0.0 1e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) DUF4577 PF15145.1 KZN91673.1 - 0.044 13.6 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DC_STAMP PF07782.8 KZN91673.1 - 0.046 13.3 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein DUF4330 PF14221.1 KZN91673.1 - 0.05 13.4 0.1 0.055 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Phosphoesterase PF04185.9 KZN91675.1 - 2.9e-43 148.5 2.7 2.4e-42 145.4 1.9 1.9 1 1 0 1 1 1 1 Phosphoesterase family Saccharop_dh PF03435.13 KZN91675.1 - 0.047 12.6 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase VIT1 PF01988.14 KZN91676.1 - 1.8e-58 197.5 2.6 2.1e-58 197.3 1.8 1.0 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.6 KZN91676.1 - 0.004 16.8 1.9 0.0059 16.2 1.3 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling Abhydrolase_9_N PF15420.1 KZN91676.1 - 0.076 12.7 0.4 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2948 PF11164.3 KZN91677.1 - 0.13 11.8 0.2 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) PAP2 PF01569.16 KZN91678.1 - 1.1e-14 54.2 5.9 1.1e-14 54.2 4.1 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KZN91678.1 - 4.5e-07 29.5 5.1 1e-06 28.4 3.5 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KZN91678.1 - 2.6 8.3 8.9 0.72 10.1 3.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal LCAT PF02450.10 KZN91679.1 - 2.3e-97 326.4 0.0 2.7e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KZN91679.1 - 0.018 14.3 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 2) BAAT_C PF08840.6 KZN91679.1 - 0.035 13.7 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KZN91679.1 - 0.053 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 KZN91679.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.19 KZN91680.1 - 2.1e-17 62.9 0.0 3.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN91680.1 - 2.3e-11 43.8 0.0 3.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN91680.1 - 3.4e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN91680.1 - 1.4e-10 40.7 0.0 2.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KZN91680.1 - 6.8e-09 36.0 0.0 9.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN91680.1 - 6.1e-07 29.4 0.0 8.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN91680.1 - 1.9e-05 24.5 0.0 3.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN91680.1 - 0.00016 21.6 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN91680.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KZN91680.1 - 0.011 15.3 0.1 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 KZN91680.1 - 0.019 13.8 0.3 0.04 12.7 0.0 1.5 2 0 0 2 2 2 0 GNAT acetyltransferase Serglycin PF04360.7 KZN91682.1 - 3.7 7.2 8.1 11 5.7 5.1 2.0 2 1 0 2 2 2 0 Serglycin Mis14 PF08641.7 KZN91683.1 - 2.7e-31 108.4 3.8 4.9e-31 107.6 2.3 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.15 KZN91684.1 - 3.8e-36 123.9 0.0 5e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KZN91684.1 - 1.5e-10 41.0 2.1 2.7e-10 40.2 0.5 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KZN91684.1 - 3.8e-06 26.8 0.0 9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 KZN91685.1 - 2.8e-55 187.0 0.1 7.3e-55 185.6 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KZN91685.1 - 1.3e-31 109.2 0.6 1.3e-31 109.2 0.4 2.3 2 0 0 2 2 2 1 RasGAP C-terminus CD36 PF01130.16 KZN91685.1 - 0.064 11.5 0.1 0.12 10.5 0.0 1.4 1 0 0 1 1 1 0 CD36 family zf-ZPR1 PF03367.8 KZN91685.1 - 0.23 10.5 0.9 0.52 9.4 0.1 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF972 PF06156.8 KZN91685.1 - 0.3 11.4 4.1 17 5.8 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DNA_pol_A_exo1 PF01612.15 KZN91686.1 - 7.5e-40 136.2 1.4 9.2e-40 135.9 0.0 1.9 3 0 0 3 3 3 1 3'-5' exonuclease PMC2NT PF08066.7 KZN91686.1 - 4.6e-27 94.1 0.1 1.3e-26 92.6 0.1 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KZN91686.1 - 2.7e-10 39.8 0.0 5.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain UPF0203 PF05254.7 KZN91687.1 - 1.8e-28 98.1 1.4 2.1e-28 97.9 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KZN91687.1 - 0.0018 18.2 0.5 0.0039 17.1 0.3 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KZN91687.1 - 0.0035 17.0 1.6 0.067 12.9 1.1 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3826 PF12875.2 KZN91687.1 - 0.066 12.9 0.1 0.084 12.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) UCR_hinge PF02320.11 KZN91687.1 - 0.086 12.7 0.4 6.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Gpi1 PF05024.10 KZN91688.1 - 3.8e-62 209.3 8.4 3.8e-62 209.3 5.8 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.16 KZN91689.1 - 1.3e-94 315.9 0.0 2.1e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN91689.1 - 3.1e-38 131.6 0.9 6.5e-38 130.5 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KZN91689.1 - 3.5e-18 65.5 1.0 1.2e-17 63.8 0.7 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KZN91689.1 - 4.3e-18 65.6 0.3 2e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 KZN91689.1 - 7.1e-15 55.0 0.0 3.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain I Vip3A_N PF12495.3 KZN91689.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Pkinase PF00069.20 KZN91691.1 - 8.7e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KZN91691.1 - 6.2e-07 28.6 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN91691.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KZN91691.1 - 0.017 14.1 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 KZN91691.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KZN91691.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TroA PF01297.12 KZN91692.1 - 0.0016 17.7 0.4 0.0025 17.1 0.3 1.2 1 0 0 1 1 1 1 Periplasmic solute binding protein family PG_binding_4 PF12229.3 KZN91692.1 - 0.005 17.0 0.9 0.0086 16.3 0.4 1.5 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Syntaxin PF00804.20 KZN91692.1 - 0.0099 16.0 2.9 0.013 15.6 1.9 1.3 1 1 0 1 1 1 1 Syntaxin DUF883 PF05957.8 KZN91692.1 - 0.011 16.0 7.6 0.03 14.7 2.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FadA PF09403.5 KZN91692.1 - 0.034 14.1 2.4 0.033 14.1 1.3 1.3 1 1 0 1 1 1 0 Adhesion protein FadA Apolipoprotein PF01442.13 KZN91692.1 - 0.097 12.1 4.1 0.21 11.0 2.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Hydrolase_6 PF13344.1 KZN91692.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3072 PF11272.3 KZN91692.1 - 0.47 10.1 2.1 18 5.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3072) V-ATPase_G PF03179.10 KZN91692.1 - 0.59 10.4 5.7 1.1 9.5 4.0 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KZN91692.1 - 0.97 9.2 7.7 1.4 8.6 5.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) rRNA_processing PF08524.6 KZN91692.1 - 1.4 8.7 6.3 1.6 8.4 4.2 1.3 1 1 0 1 1 1 0 rRNA processing zf-H2C2_2 PF13465.1 KZN91693.1 - 6e-06 26.2 4.0 6e-06 26.2 2.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KZN91693.1 - 3.1e-05 24.0 13.0 0.011 15.9 1.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN91693.1 - 3.3e-05 23.9 14.7 0.0043 17.2 1.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger TylF PF05711.6 KZN91693.1 - 0.11 11.5 0.0 0.53 9.3 0.0 1.8 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-C2H2_6 PF13912.1 KZN91693.1 - 2.8 7.9 5.8 0.33 10.9 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger SEO_N PF14576.1 KZN91694.1 - 0.062 12.5 0.1 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus COG5 PF10392.4 KZN91696.1 - 1.7e-40 138.0 0.5 1.7e-40 138.0 0.4 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Aldolase_II PF00596.16 KZN91697.1 - 3.7e-46 157.0 0.1 4.8e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SYS1 PF09801.4 KZN91698.1 - 1e-53 181.1 7.0 1.2e-53 180.9 4.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MFS_1 PF07690.11 KZN91698.1 - 0.015 13.9 10.7 0.019 13.6 7.4 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily COX6B PF02297.12 KZN91699.1 - 3.3e-23 81.4 4.0 4.2e-23 81.1 2.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KZN91699.1 - 0.016 15.2 1.0 0.023 14.6 0.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 RRM_1 PF00076.17 KZN91700.1 - 1.2e-08 34.4 0.0 1.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN91700.1 - 3.9e-06 26.7 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hairy_orange PF07527.8 KZN91700.1 - 0.067 12.9 0.5 6.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Hairy Orange RRM_5 PF13893.1 KZN91700.1 - 0.15 11.9 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U3_assoc_6 PF08640.6 KZN91701.1 - 3.1e-29 100.5 0.7 3.1e-29 100.5 0.5 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 KZN91701.1 - 0.0017 18.1 0.6 0.81 9.3 0.0 3.0 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KZN91701.1 - 0.0022 18.4 0.5 1.8 9.3 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KZN91701.1 - 0.024 13.7 0.0 0.12 11.4 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Frag1 PF10277.4 KZN91702.1 - 4.6e-44 150.4 9.2 4.6e-44 150.4 6.4 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family ABC2_membrane_2 PF12679.2 KZN91702.1 - 0.16 10.8 8.1 0.068 12.0 3.3 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein CPSF100_C PF13299.1 KZN91704.1 - 7.6e-44 149.7 0.0 1.7e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KZN91704.1 - 2.3e-28 98.6 0.0 1.4e-27 96.1 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 KZN91704.1 - 0.00026 20.7 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KZN91704.1 - 0.0097 15.5 0.2 0.047 13.3 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.1 KZN91705.1 - 9.4e-56 189.1 47.2 1.2e-55 188.7 32.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN91705.1 - 2e-19 69.2 38.7 2.7e-19 68.8 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease COPI_assoc PF08507.5 KZN91705.1 - 0.51 10.0 9.0 5.5 6.6 1.4 3.2 3 0 0 3 3 3 0 COPI associated protein DUF485 PF04341.7 KZN91705.1 - 3.4 7.4 8.2 0.35 10.6 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Sec23_trunk PF04811.10 KZN91706.1 - 8.1e-54 182.5 0.0 2.3e-53 181.0 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KZN91706.1 - 5.5e-26 89.9 0.0 9.9e-26 89.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KZN91706.1 - 1.3e-17 64.0 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KZN91706.1 - 2e-16 59.2 5.6 3.7e-16 58.4 3.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KZN91706.1 - 3.4e-08 33.0 0.0 7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.6 KZN91706.1 - 0.23 10.9 0.0 0.62 9.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Gti1_Pac2 PF09729.4 KZN91707.1 - 7.1e-50 169.1 4.7 1.1e-49 168.4 0.4 2.7 2 1 0 2 2 2 1 Gti1/Pac2 family tRNA-synt_2 PF00152.15 KZN91708.1 - 2.2e-57 194.3 0.0 3.3e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN91708.1 - 8.3e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.17 KZN91709.1 - 4.7e-12 45.3 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN91709.1 - 3e-09 36.7 0.0 5.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN91709.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3763 PF12592.3 KZN91709.1 - 0.13 11.9 2.8 0.42 10.2 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) Prominin PF05478.6 KZN91709.1 - 0.32 8.4 0.1 0.48 7.9 0.1 1.1 1 0 0 1 1 1 0 Prominin MOZ_SAS PF01853.13 KZN91710.1 - 9.1e-55 184.8 0.0 3.1e-53 179.8 0.0 2.1 1 1 0 1 1 1 1 MOZ/SAS family Cpn60_TCP1 PF00118.19 KZN91711.1 - 2.6e-149 497.9 0.1 3e-149 497.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nop PF01798.13 KZN91712.1 - 3e-61 205.1 0.0 6.6e-61 203.9 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KZN91712.1 - 5.9e-25 86.8 0.4 1.2e-24 85.8 0.3 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KZN91712.1 - 4.3e-22 78.0 0.1 4.3e-22 78.0 0.1 3.0 4 0 0 4 4 4 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KZN91712.1 - 0.29 10.7 32.9 0.62 9.6 22.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 KZN91712.1 - 0.93 9.2 6.3 1.8 8.3 4.3 1.5 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 KZN91712.1 - 4.9 6.0 10.3 8.2 5.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAGA_bind PF06217.7 KZN91712.1 - 5.9 6.7 18.1 1.4 8.8 10.3 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family PAT1 PF09770.4 KZN91713.1 - 0.046 11.9 1.0 0.051 11.8 0.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3767 PF12597.3 KZN91714.1 - 2.6e-36 123.8 0.0 4.2e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) TMA7 PF09072.5 KZN91714.1 - 0.028 14.9 4.0 0.052 14.0 2.8 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF1744 PF08490.7 KZN91715.1 - 8.8e-149 495.3 0.0 1.3e-148 494.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KZN91715.1 - 4.4e-71 239.3 1.3 1.9e-70 237.2 0.8 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KZN91715.1 - 6.8e-22 77.8 0.0 3.1e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KZN91715.1 - 1.3e-07 31.4 0.0 3.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KZN91715.1 - 7.6e-05 22.5 0.0 0.00037 20.3 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Pkinase PF00069.20 KZN91716.1 - 2.4e-70 236.6 0.0 3.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91716.1 - 9.2e-31 106.8 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN91716.1 - 1.1e-06 27.8 0.0 2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN91716.1 - 0.00018 20.6 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN91716.1 - 0.0002 21.1 0.1 0.00035 20.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KZN91716.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 KZN91717.1 - 1.4e-38 131.7 0.0 2.9e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 PBP_sp32 PF07222.7 KZN91717.1 - 0.017 14.3 6.8 0.029 13.5 4.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sigma70_ner PF04546.8 KZN91717.1 - 0.051 13.1 6.3 0.075 12.6 4.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF572 PF04502.8 KZN91717.1 - 0.062 12.5 6.0 0.08 12.1 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 KZN91717.1 - 3.2 6.0 9.1 4.1 5.7 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HNH_2 PF13391.1 KZN91718.1 - 3.7e-16 58.6 0.0 1.4e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease SHMT PF00464.14 KZN91719.1 - 2.3e-208 691.4 0.0 2.7e-208 691.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KZN91719.1 - 3.1e-07 29.6 0.0 7.5e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KZN91719.1 - 4.8e-05 22.2 0.0 7.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KZN91719.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KZN91719.1 - 0.079 11.3 0.4 0.35 9.2 0.1 2.2 2 1 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain Med9 PF07544.8 KZN91720.1 - 5.2e-25 87.0 0.0 7.4e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF2730 PF10805.3 KZN91720.1 - 0.0065 16.1 0.1 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Med21 PF11221.3 KZN91720.1 - 0.3 11.0 1.4 0.57 10.1 1.0 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Metalloenzyme PF01676.13 KZN91721.1 - 7.4e-73 245.0 0.0 8.4e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KZN91721.1 - 7.1e-69 231.5 0.0 9.5e-69 231.1 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KZN91721.1 - 7e-10 38.7 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KZN91721.1 - 7e-05 22.1 0.0 0.00014 21.1 0.0 1.7 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 KZN91721.1 - 0.032 12.9 0.0 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.15 KZN91722.1 - 1.6e-22 79.3 13.4 2e-22 78.9 9.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KZN91722.1 - 0.0046 16.6 4.9 0.0076 15.9 3.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.6 KZN91722.1 - 0.012 15.2 15.6 0.031 13.9 3.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.4 KZN91722.1 - 0.014 15.5 7.9 0.46 10.6 0.9 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 KZN91722.1 - 0.018 14.6 20.0 0.037 13.6 13.9 1.5 1 1 0 1 1 1 0 IncA protein DUF3727 PF12527.3 KZN91722.1 - 0.047 13.7 3.4 1.5 8.9 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3727) Atg14 PF10186.4 KZN91722.1 - 0.1 11.5 11.1 0.12 11.2 7.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 KZN91722.1 - 0.15 11.6 12.4 0.36 10.4 8.6 1.6 1 1 0 1 1 1 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KZN91722.1 - 0.27 10.9 12.2 0.3 10.8 1.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GreA_GreB_N PF03449.10 KZN91722.1 - 0.3 11.1 8.0 2 8.5 0.3 3.3 2 2 1 3 3 3 0 Transcription elongation factor, N-terminal Cast PF10174.4 KZN91722.1 - 0.33 8.9 16.8 0.12 10.4 8.7 1.8 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone COG2 PF06148.6 KZN91722.1 - 0.34 10.7 9.2 0.47 10.3 1.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1640 PF07798.6 KZN91722.1 - 0.38 10.7 11.1 0.034 14.1 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) AAA_27 PF13514.1 KZN91722.1 - 0.51 7.9 14.6 0.54 7.8 10.1 1.0 1 0 0 1 1 1 0 AAA domain DUF904 PF06005.7 KZN91722.1 - 0.61 10.4 17.5 1.3 9.4 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SpecificRecomb PF10136.4 KZN91722.1 - 0.75 7.7 5.6 0.85 7.5 3.9 1.0 1 0 0 1 1 1 0 Site-specific recombinase APG6 PF04111.7 KZN91722.1 - 0.78 8.7 16.9 0.021 13.8 3.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KZN91722.1 - 0.79 10.1 10.1 3.3 8.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 KZN91722.1 - 0.89 9.0 17.9 0.68 9.4 1.2 3.1 2 1 1 3 3 3 0 Septum formation initiator Streptin-Immun PF11083.3 KZN91722.1 - 0.9 9.5 5.8 1.3 9.0 0.4 2.3 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein Viral_P18 PF04521.8 KZN91722.1 - 1.4 8.3 7.7 4.4 6.7 0.8 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Fez1 PF06818.10 KZN91722.1 - 1.5 8.8 14.7 0.075 13.0 1.7 2.0 1 1 1 2 2 2 0 Fez1 GAS PF13851.1 KZN91722.1 - 1.9 7.6 14.4 3.1 6.9 3.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KZN91722.1 - 2 8.1 17.8 3.5 7.3 3.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 KZN91722.1 - 2.2 8.3 17.9 2.1 8.4 4.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Spc7 PF08317.6 KZN91722.1 - 2.5 6.6 13.0 3.6 6.1 9.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.13 KZN91722.1 - 2.7 6.9 6.3 0.54 9.2 0.5 1.9 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Nup54 PF13874.1 KZN91722.1 - 4.1 7.0 12.6 0.8 9.3 2.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Occludin_ELL PF07303.8 KZN91722.1 - 4.3 8.1 8.3 9.4 7.0 2.2 2.2 1 1 1 2 2 2 0 Occludin homology domain SPX PF03105.14 KZN91722.1 - 4.6 6.9 7.2 5.8 6.6 5.0 1.2 1 0 0 1 1 1 0 SPX domain DUF4140 PF13600.1 KZN91722.1 - 4.6 7.7 15.6 6.9 7.1 3.2 2.9 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sas10_Utp3 PF04000.10 KZN91722.1 - 4.8 7.4 7.3 3 8.0 1.1 2.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family PEP-utilisers_N PF05524.8 KZN91722.1 - 5 6.9 9.9 0.7 9.7 1.3 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Tropomyosin_1 PF12718.2 KZN91722.1 - 5.9 6.7 19.3 0.78 9.5 3.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Macoilin PF09726.4 KZN91722.1 - 6.6 4.8 14.4 17 3.5 10.0 1.6 1 1 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 KZN91722.1 - 9.8 6.2 9.5 1 9.4 0.9 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 KZN91722.1 - 10 6.5 12.7 0.27 11.5 0.8 2.4 2 1 0 2 2 2 0 Snapin/Pallidin AAA PF00004.24 KZN91723.1 - 2.8e-42 144.0 0.0 4.7e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KZN91723.1 - 1.6e-29 101.5 0.1 7.8e-29 99.3 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KZN91723.1 - 3.6e-22 78.0 1.4 3.6e-22 78.0 1.0 2.5 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KZN91723.1 - 2.3e-06 28.4 0.3 1e-05 26.3 0.0 2.5 2 2 1 3 3 1 1 AAA domain RuvB_N PF05496.7 KZN91723.1 - 9.8e-06 24.7 0.0 1.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN91723.1 - 1.5e-05 24.7 0.0 8.5e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN91723.1 - 1.7e-05 24.9 0.1 0.0013 18.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN91723.1 - 2.7e-05 23.6 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 KZN91723.1 - 3.9e-05 22.7 0.0 0.0011 17.9 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KZN91723.1 - 3.9e-05 23.7 0.0 0.0091 16.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KZN91723.1 - 4e-05 23.1 0.5 0.19 11.0 0.1 3.5 3 1 1 4 4 4 2 AAA domain AAA_14 PF13173.1 KZN91723.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN91723.1 - 0.00011 22.2 0.0 0.0011 19.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KZN91723.1 - 0.00013 20.8 0.0 0.00022 20.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KZN91723.1 - 0.00015 21.7 0.0 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KZN91723.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN91723.1 - 0.0048 17.2 0.2 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KZN91723.1 - 0.0082 15.8 0.3 0.31 10.6 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 KZN91723.1 - 0.0087 15.6 0.1 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KZN91723.1 - 0.016 14.3 0.0 0.058 12.5 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KZN91723.1 - 0.022 13.8 0.1 0.14 11.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KZN91723.1 - 0.024 14.4 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain USP8_dimer PF08969.6 KZN91723.1 - 0.027 14.4 2.8 0.056 13.3 1.9 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain NACHT PF05729.7 KZN91723.1 - 0.027 14.1 0.0 0.62 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 KZN91723.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Torsin PF06309.6 KZN91723.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 KZN91723.1 - 0.039 13.1 0.0 0.092 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KZN91723.1 - 0.053 12.3 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KZN91723.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KZN91723.1 - 0.16 11.5 0.0 0.62 9.6 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein Microtub_assoc PF07989.6 KZN91724.1 - 4.6e-24 84.0 5.4 4.6e-24 84.0 3.7 11.5 9 3 5 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 KZN91724.1 - 1.8e-23 82.2 0.9 7.4e-23 80.2 0.6 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Atg14 PF10186.4 KZN91724.1 - 0.0026 16.7 10.7 0.0026 16.7 7.4 8.8 1 1 8 9 9 9 1 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KZN91724.1 - 0.0092 15.8 8.8 0.0092 15.8 6.1 12.6 1 1 9 11 11 11 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KZN91724.1 - 0.63 9.1 44.9 0.069 12.3 3.0 6.4 1 1 2 6 6 6 0 Reovirus sigma C capsid protein SGT1 PF07093.6 KZN91725.1 - 2.6e-149 498.3 24.4 5.6e-148 493.9 16.9 2.0 1 1 0 1 1 1 1 SGT1 protein PAS_9 PF13426.1 KZN91725.1 - 0.018 15.4 0.0 0.059 13.7 0.0 1.9 1 0 0 1 1 1 0 PAS domain Folliculin PF11704.3 KZN91726.1 - 5e-46 156.3 0.0 7.1e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PCI_Csn8 PF10075.4 KZN91727.1 - 9.6e-48 161.5 0.0 1.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KZN91727.1 - 1.9e-21 76.5 0.1 2.5e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pkinase PF00069.20 KZN91728.1 - 3.8e-35 121.2 0.0 5.9e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91728.1 - 5.4e-13 48.5 0.0 3e-11 42.9 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KZN91728.1 - 0.011 14.5 0.3 0.022 13.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KZN91728.1 - 0.031 14.0 0.3 0.81 9.3 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KZN91728.1 - 0.16 11.2 1.1 0.34 10.2 0.1 2.0 3 0 0 3 3 3 0 RIO1 family PDCD2_C PF04194.8 KZN91729.1 - 3.1e-52 176.4 0.0 5.7e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 KZN91729.1 - 0.02 14.3 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain Prenylcys_lyase PF07156.9 KZN91730.1 - 8.8e-37 126.8 0.0 2e-35 122.3 0.0 2.3 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KZN91730.1 - 9e-13 48.0 0.0 1.9e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KZN91730.1 - 2.2e-07 30.3 0.0 1.1e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KZN91730.1 - 5.1e-06 25.6 0.2 0.0029 16.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN91730.1 - 0.00047 19.9 0.2 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Abhydrolase_3 PF07859.8 KZN91730.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pyr_redox_3 PF13738.1 KZN91730.1 - 0.072 13.1 0.0 0.68 9.9 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91730.1 - 0.081 12.7 0.4 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN91730.1 - 0.09 11.2 0.1 0.78 8.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GATase PF00117.23 KZN91731.1 - 9.6e-41 139.3 0.0 1.7e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KZN91731.1 - 1.4e-33 114.5 0.0 4.1e-33 112.9 0.0 1.9 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KZN91731.1 - 6.9e-10 38.2 0.1 3.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KZN91731.1 - 9.4e-06 25.2 0.1 2.8e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 KZN91731.1 - 0.00023 19.8 0.2 0.00055 18.5 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 KZN91731.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 KZN91731.1 - 0.0035 16.4 0.1 0.005 15.9 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.9 KZN91731.1 - 0.0037 16.7 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 KZN91731.1 - 0.0051 16.1 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KZN91731.1 - 0.043 13.3 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase Clp1 PF06807.9 KZN91732.1 - 1.5e-08 34.6 0.0 1.1e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KZN91732.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KZN91732.1 - 0.0022 18.8 0.0 0.013 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN91732.1 - 0.0052 16.6 2.2 0.018 14.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KZN91732.1 - 0.038 14.1 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 KZN91732.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KZN91732.1 - 0.29 9.7 0.0 0.44 9.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_polI_A34 PF08208.6 KZN91733.1 - 1.2e-36 126.3 20.0 1.2e-36 126.3 13.9 2.5 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 GRAM PF02893.15 KZN91734.1 - 1.9e-29 100.9 0.9 5e-18 64.3 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KZN91734.1 - 2.7e-23 82.2 0.0 5.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KZN91734.1 - 1.6e-16 60.3 0.0 1.6e-15 57.1 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KZN91734.1 - 1.1e-07 32.0 2.4 2.4e-07 30.9 0.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 KZN91734.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KZN91734.1 - 0.00025 21.0 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 KZN91734.1 - 0.015 13.8 0.0 0.025 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.12 KZN91735.1 - 9.7e-29 99.4 0.1 1.8e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KZN91735.1 - 4.3e-05 23.2 1.0 0.00021 21.0 0.0 2.2 2 1 0 2 2 2 1 Prefoldin subunit DUF4201 PF13870.1 KZN91735.1 - 0.0013 18.1 0.9 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Filament PF00038.16 KZN91735.1 - 0.0076 15.7 2.1 0.14 11.5 0.1 2.0 1 1 1 2 2 2 1 Intermediate filament protein HR1 PF02185.11 KZN91735.1 - 0.0092 15.6 0.3 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Hr1 repeat Syntaxin-6_N PF09177.6 KZN91735.1 - 0.015 15.6 0.5 4 7.9 0.0 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KZN91735.1 - 0.17 11.7 2.6 19 5.2 0.2 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Vma12 PF11712.3 KZN91736.1 - 7.8e-34 116.4 0.0 1e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PsbN PF02468.10 KZN91736.1 - 0.46 10.1 1.9 1 9.0 1.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Amidohydro_4 PF13147.1 KZN91737.1 - 7.9e-21 75.3 0.3 2.8e-20 73.5 0.2 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN91737.1 - 3.6e-20 72.8 0.5 1.3e-11 44.7 0.0 3.0 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 KZN91737.1 - 6.4e-10 38.7 0.1 2.3e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN91737.1 - 3.8e-07 29.6 0.0 0.00069 18.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Arb2 PF09757.4 KZN91738.1 - 2.1e-09 37.0 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Abhydrolase_6 PF12697.2 KZN91738.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_S14 PF00253.16 KZN91739.1 - 4.7e-20 70.7 0.3 2.2e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e ATP-synt_J PF04911.7 KZN91740.1 - 5.5e-22 76.9 0.7 6e-22 76.8 0.5 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 KZN91741.1 - 1e-51 174.5 4.5 1.3e-51 174.2 3.1 1.1 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 KZN91741.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.4 1 1 0 1 1 1 0 Mur ligase middle domain COG5 PF10392.4 KZN91741.1 - 1.4 8.9 7.8 7.7 6.4 0.1 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Rsm22 PF09243.5 KZN91742.1 - 5.1e-32 111.0 0.1 4.9e-30 104.4 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Rogdi_lz PF10259.4 KZN91743.1 - 4.3e-79 265.4 0.0 4.9e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.7 KZN91744.1 - 4.4e-39 134.2 10.1 5.1e-39 134.0 7.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KZN91744.1 - 0.00012 21.8 12.0 0.00012 21.8 8.3 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KZN91744.1 - 0.0034 16.6 0.3 0.0034 16.6 0.2 1.5 2 0 0 2 2 2 1 Clc-like Amastin PF07344.6 KZN91744.1 - 1.1 8.8 15.5 1.4 8.5 9.8 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Fig1 PF12351.3 KZN91744.1 - 1.5 8.7 8.5 0.72 9.7 4.1 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4064 PF13273.1 KZN91744.1 - 4.4 7.4 7.6 15 5.8 2.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) HSP70 PF00012.15 KZN91745.1 - 2.3e-82 276.8 1.1 2.3e-82 276.8 0.8 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KZN91745.1 - 2.9e-09 35.9 0.2 4.4e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.1 KZN91745.1 - 0.0058 16.0 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein DUF2067 PF09840.4 KZN91746.1 - 0.065 12.7 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) DUF261 PF03196.8 KZN91746.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 Myb_DNA-bind_6 PF13921.1 KZN91747.1 - 3.9e-16 58.9 6.8 6.5e-12 45.3 0.9 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN91747.1 - 3e-14 52.7 7.7 2.3e-07 30.7 0.3 3.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain UDP-g_GGTase PF06427.6 KZN91748.1 - 3.1e-68 229.2 0.0 5.7e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KZN91748.1 - 0.00033 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpp20 PF12328.3 KZN91750.1 - 6.6e-52 174.9 13.1 1e-51 174.4 9.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KZN91750.1 - 1.2e-25 88.8 1.9 2e-25 88.1 1.3 1.3 1 0 0 1 1 1 1 Alba DUF1529 PF07485.6 KZN91750.1 - 0.012 15.3 0.3 0.021 14.5 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) ATG2_CAD PF13329.1 KZN91750.1 - 0.02 14.4 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif FYDLN_acid PF09538.5 KZN91750.1 - 1.2 9.8 0.0 1.2 9.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) TruB_N PF01509.13 KZN91750.1 - 3.3 7.8 6.1 1.7 8.8 1.6 2.0 1 1 1 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) SynMuv_product PF06047.6 KZN91750.1 - 3.4 7.4 7.6 0.25 11.0 0.5 2.3 2 0 0 2 2 2 0 Ras-induced vulval development antagonist FHA PF00498.21 KZN91751.1 - 4.8e-17 61.8 0.0 1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain EMP24_GP25L PF01105.19 KZN91751.1 - 0.18 11.5 1.9 0.48 10.1 0.5 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2408 PF10303.4 KZN91751.1 - 1.9 8.6 11.6 0.058 13.5 2.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) COG2 PF06148.6 KZN91751.1 - 1.9 8.3 10.5 0.12 12.2 2.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IFT57 PF10498.4 KZN91751.1 - 2 7.1 16.2 0.3 9.7 2.5 2.7 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Romo1 PF10247.4 KZN91752.1 - 5.3e-29 100.2 13.6 6.7e-29 99.8 9.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TMEM141 PF15110.1 KZN91752.1 - 1.7 9.0 4.0 2.9 8.2 0.6 2.0 1 1 1 2 2 2 0 TMEM141 protein family Tim17 PF02466.14 KZN91752.1 - 3.2 7.8 9.0 16 5.5 6.2 1.9 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ABC_tran PF00005.22 KZN91753.1 - 6.5e-35 120.4 0.0 1.9e-34 118.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 KZN91753.1 - 2.2e-17 63.4 5.4 4.1e-17 62.4 3.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KZN91753.1 - 5.1e-08 32.4 0.0 1e-05 24.9 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 KZN91753.1 - 0.00025 20.9 0.0 0.27 11.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KZN91753.1 - 0.00053 20.0 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KZN91753.1 - 0.0012 19.6 0.0 0.0035 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KZN91753.1 - 0.0023 17.9 0.0 0.016 15.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KZN91753.1 - 0.0025 16.9 1.6 0.012 14.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 KZN91753.1 - 0.0032 17.8 0.7 0.005 17.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KZN91753.1 - 0.0033 17.5 0.0 0.0093 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Herpes_gE PF02480.11 KZN91753.1 - 0.0041 15.4 0.5 0.008 14.4 0.0 1.6 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E AAA_18 PF13238.1 KZN91753.1 - 0.0049 17.1 0.1 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 KZN91753.1 - 0.0098 15.7 0.8 0.086 12.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_29 PF13555.1 KZN91753.1 - 0.013 15.0 0.1 0.04 13.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KZN91753.1 - 0.017 15.3 0.0 0.17 12.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KZN91753.1 - 0.02 14.8 1.1 0.51 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1510 PF07423.6 KZN91753.1 - 0.04 13.2 2.5 0.082 12.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NB-ARC PF00931.17 KZN91753.1 - 0.051 12.4 0.1 0.094 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KZN91753.1 - 0.088 12.5 0.2 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KZN91753.1 - 0.12 11.7 0.2 0.37 10.2 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KZN91753.1 - 0.13 11.9 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KZN91753.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KZN91753.1 - 0.24 11.0 3.5 1.4 8.5 0.2 3.0 4 0 0 4 4 4 0 NACHT domain G-alpha PF00503.15 KZN91753.1 - 0.49 9.0 2.6 0.38 9.3 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit LRR_8 PF13855.1 KZN91755.1 - 4.6e-13 48.7 18.4 1.3e-07 31.2 4.7 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KZN91755.1 - 8.8e-13 47.5 16.2 1.1e-09 37.6 2.3 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KZN91755.1 - 4.4e-06 25.9 8.8 0.2 11.8 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KZN91755.1 - 0.0003 20.4 4.5 0.31 11.4 0.1 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KZN91755.1 - 0.097 12.7 3.1 17 5.9 0.3 3.2 3 0 0 3 3 3 0 Leucine Rich repeat adh_short PF00106.20 KZN91756.1 - 1.1e-29 103.5 1.3 1.4e-29 103.1 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN91756.1 - 4.5e-16 59.3 0.0 5.9e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN91756.1 - 5.4e-16 58.7 0.3 7.9e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN91756.1 - 1.4e-07 31.7 0.1 3.4e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN91756.1 - 0.00022 20.7 0.1 0.0018 17.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KZN91756.1 - 0.00097 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KZN91756.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-RING_2 PF13639.1 KZN91757.1 - 1.7e-14 53.3 5.8 2.8e-14 52.6 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KZN91757.1 - 5e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KZN91757.1 - 2.9e-09 36.7 5.4 4.7e-09 36.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN91757.1 - 3.2e-08 33.5 3.8 5.8e-08 32.7 2.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KZN91757.1 - 5.3e-08 32.4 3.8 8.6e-08 31.7 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN91757.1 - 9.3e-08 31.6 3.3 1.4e-07 31.0 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN91757.1 - 1.4e-07 31.0 2.8 2.3e-07 30.4 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KZN91757.1 - 0.001 18.8 1.0 0.0018 18.0 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KZN91757.1 - 0.0051 16.5 3.0 0.012 15.3 2.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 KZN91757.1 - 0.074 13.0 2.4 0.2 11.6 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KZN91757.1 - 0.087 12.8 4.5 0.16 12.0 3.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KZN91757.1 - 0.19 11.6 3.1 0.55 10.1 2.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KZN91757.1 - 0.45 10.1 3.4 0.81 9.3 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KZN91757.1 - 2.2 8.3 4.0 4.3 7.4 2.8 1.5 1 0 0 1 1 1 0 RING-like domain adh_short PF00106.20 KZN91759.1 - 5.5e-15 55.6 0.0 8.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN91759.1 - 3.4e-07 30.1 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN91759.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Raptor_N PF14538.1 KZN91760.1 - 1.3e-63 213.5 0.0 2.2e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KZN91760.1 - 2.7e-06 27.0 6.0 1.1 9.2 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KZN91760.1 - 0.0021 17.7 0.2 1.5 8.6 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Peptidase_C14 PF00656.17 KZN91760.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Kelch_3 PF13415.1 KZN91761.1 - 9e-36 121.2 10.8 4.9e-08 32.9 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KZN91761.1 - 4.9e-31 106.1 3.6 1e-05 25.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KZN91761.1 - 4.3e-30 103.2 10.5 8e-06 25.5 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KZN91761.1 - 6.5e-29 99.2 0.7 2.8e-09 36.3 0.2 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KZN91761.1 - 1.9e-24 84.7 8.7 4.4e-09 36.1 0.3 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KZN91761.1 - 6.4e-18 63.7 8.2 1.4e-05 24.6 0.1 6.4 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KZN91761.1 - 0.0095 14.6 0.1 0.17 10.6 0.0 2.8 4 0 0 4 4 4 1 Recombination activating protein 2 Pkinase PF00069.20 KZN91762.1 - 4.3e-38 130.9 0.0 5.5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91762.1 - 8.2e-14 51.2 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN91762.1 - 3e-05 23.8 0.0 0.0017 18.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family bZIP_1 PF00170.16 KZN91763.1 - 9.6e-10 38.2 11.4 1.5e-09 37.6 7.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN91763.1 - 2.6e-05 23.9 15.2 2.8e-05 23.8 9.8 1.6 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KZN91763.1 - 0.00075 19.7 8.8 0.0012 19.0 6.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MIS13 PF08202.6 KZN91763.1 - 0.0022 17.1 1.1 0.003 16.6 0.8 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF972 PF06156.8 KZN91763.1 - 0.0047 17.2 0.2 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KZN91763.1 - 0.017 15.0 0.3 0.028 14.2 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glutaredoxin2_C PF04399.8 KZN91763.1 - 0.019 14.5 1.9 0.033 13.7 1.3 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TMF_TATA_bd PF12325.3 KZN91763.1 - 0.048 13.3 2.6 0.09 12.5 1.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.6 KZN91763.1 - 0.064 11.7 5.7 0.086 11.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_UL6 PF01763.11 KZN91763.1 - 0.065 11.4 0.8 0.083 11.0 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Effector_1 PF04518.7 KZN91763.1 - 0.076 11.9 4.2 0.1 11.5 2.9 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF724 PF05266.9 KZN91763.1 - 0.098 12.2 5.7 0.16 11.5 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.10 KZN91763.1 - 0.14 11.7 4.8 0.27 10.7 3.3 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 KZN91763.1 - 0.17 9.7 0.8 0.21 9.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KZN91763.1 - 0.3 10.0 4.2 0.4 9.6 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KZN91763.1 - 0.32 10.5 1.9 0.47 10.0 1.3 1.2 1 0 0 1 1 1 0 IncA protein Phosducin PF02114.11 KZN91764.1 - 2.8e-11 42.6 0.1 3.8e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Phosducin Pup PF05639.6 KZN91764.1 - 0.063 13.7 1.6 0.063 13.7 1.1 2.0 2 1 1 3 3 3 0 Pup-like protein Adaptin_N PF01602.15 KZN91765.1 - 5.8e-110 368.0 0.2 7.7e-110 367.6 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KZN91765.1 - 2.5e-58 196.1 1.1 6.4e-58 194.8 0.8 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KZN91765.1 - 9.1e-15 54.7 0.4 2.1e-05 24.6 0.0 6.0 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 KZN91765.1 - 0.00011 21.9 5.7 0.31 11.2 0.2 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KZN91765.1 - 0.0073 16.7 2.9 0.031 14.7 0.3 3.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT_PBS PF03130.11 KZN91765.1 - 0.015 15.7 4.3 12 6.7 0.0 5.3 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 KZN91765.1 - 0.11 12.3 5.4 0.19 11.5 0.2 3.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_2 PF00152.15 KZN91766.1 - 1.8e-75 253.8 0.3 2.4e-75 253.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN91766.1 - 2.2e-06 27.4 0.1 4.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1510 PF07423.6 KZN91766.1 - 0.14 11.4 3.4 0.25 10.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hydrolase_6 PF13344.1 KZN91767.1 - 1.1e-24 86.2 0.0 2.6e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN91767.1 - 4.7e-16 58.2 0.0 3.4e-15 55.4 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 KZN91767.1 - 1.4e-06 28.6 0.0 0.019 15.2 0.0 3.6 2 1 2 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN91767.1 - 1.7e-05 25.3 0.0 0.19 12.1 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.19 KZN91767.1 - 0.073 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain F-box-like PF12937.2 KZN91768.1 - 3e-06 26.8 0.2 7.8e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like NmrA PF05368.8 KZN91769.1 - 4.2e-17 62.1 0.0 8.6e-17 61.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN91769.1 - 6.1e-14 52.4 0.1 9.7e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN91769.1 - 0.00024 20.6 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN91769.1 - 0.0012 19.1 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN91769.1 - 0.0021 18.4 0.3 0.0097 16.3 0.2 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KZN91769.1 - 0.0041 17.6 0.1 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 KZN91769.1 - 0.0052 16.2 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 KZN91769.1 - 0.0097 15.8 0.3 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KZN91769.1 - 0.022 14.6 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.18 KZN91769.1 - 0.025 14.3 0.6 0.069 12.9 0.4 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KZN91769.1 - 0.17 11.5 1.2 0.87 9.2 0.8 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SIP1 PF04938.7 KZN91770.1 - 2.8e-06 26.8 0.2 0.007 15.7 0.0 3.4 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Curto_V2 PF07325.6 KZN91770.1 - 0.078 12.6 0.9 0.11 12.1 0.2 1.5 1 1 0 1 1 1 0 Curtovirus V2 protein PX PF00787.19 KZN91771.1 - 1.8e-13 50.2 0.0 3.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KZN91771.1 - 1.6e-06 27.6 5.7 1.6e-06 27.6 3.9 1.9 2 0 0 2 2 2 1 SNARE domain BCIP PF13862.1 KZN91771.1 - 0.014 14.9 0.4 0.024 14.1 0.3 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DGF-1_C PF11040.3 KZN91771.1 - 0.054 13.3 1.9 0.23 11.3 0.0 2.9 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus IBV_3A PF03617.8 KZN91772.1 - 2.1 8.1 5.3 0.24 11.1 0.3 2.0 2 0 0 2 2 2 0 IBV 3A protein Cyclase PF04199.8 KZN91773.1 - 6e-14 52.0 0.1 8.5e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.7 KZN91773.1 - 0.026 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Sugar_tr PF00083.19 KZN91774.1 - 2.8e-79 266.8 26.8 3.2e-79 266.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91774.1 - 1.6e-23 82.9 59.7 1.3e-20 73.4 24.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 KZN91774.1 - 0.11 12.1 2.5 0.27 10.9 0.4 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Acetyltransf_1 PF00583.19 KZN91775.1 - 1.8e-08 34.3 0.0 3.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN91775.1 - 0.00034 20.6 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN91775.1 - 0.0034 17.4 0.0 0.0074 16.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ecotin PF03974.8 KZN91775.1 - 0.0075 15.9 0.2 0.03 14.0 0.0 2.0 3 0 0 3 3 3 1 Ecotin Fungal_trans PF04082.13 KZN91776.1 - 1e-09 37.6 0.0 1.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3-HAO PF06052.7 KZN91776.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase zf-RING_2 PF13639.1 KZN91777.1 - 2.4e-12 46.4 7.8 4.1e-12 45.7 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KZN91777.1 - 1.2e-07 31.2 4.4 2e-07 30.5 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN91777.1 - 3.7e-07 30.0 5.2 6.8e-07 29.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN91777.1 - 5.3e-07 29.2 2.0 1e-06 28.3 1.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KZN91777.1 - 1.2e-05 24.9 5.3 1.8e-05 24.3 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KZN91777.1 - 5.7e-05 23.1 8.8 0.00014 21.8 6.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KZN91777.1 - 0.0004 19.9 3.2 0.00074 19.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN91777.1 - 0.00049 19.8 2.0 0.00073 19.3 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SKG6 PF08693.5 KZN91777.1 - 0.0016 17.7 0.2 0.003 16.8 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RINGv PF12906.2 KZN91777.1 - 0.0024 17.8 3.9 0.0024 17.8 2.7 1.8 2 1 0 2 2 1 1 RING-variant domain Rtf2 PF04641.7 KZN91777.1 - 0.0027 16.9 0.1 0.0034 16.6 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Rax2 PF12768.2 KZN91777.1 - 0.0048 16.1 0.0 0.0059 15.8 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity zf-RING_4 PF14570.1 KZN91777.1 - 0.013 15.0 4.7 0.021 14.3 3.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cad PF03596.8 KZN91777.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Cadmium resistance transporter Mid2 PF04478.7 KZN91777.1 - 0.049 13.0 1.2 0.077 12.4 0.9 1.3 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor FANCL_C PF11793.3 KZN91777.1 - 0.054 13.4 7.6 0.31 11.0 5.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain OppC_N PF12911.2 KZN91777.1 - 0.061 12.6 0.4 0.1 11.9 0.3 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C EphA2_TM PF14575.1 KZN91777.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Zn_Tnp_IS1595 PF12760.2 KZN91777.1 - 0.12 12.1 5.3 0.11 12.3 0.8 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TMEM51 PF15345.1 KZN91777.1 - 0.14 11.8 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 zf-Nse PF11789.3 KZN91777.1 - 0.29 10.6 2.0 0.48 9.9 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 KZN91777.1 - 1.1 9.1 5.8 15 5.5 4.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 KZN91777.1 - 1.9 8.2 6.5 7.2 6.4 4.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 KZN91777.1 - 5.3 6.8 6.5 19 5.0 4.5 1.9 1 1 0 1 1 1 0 PHD-finger Homeobox PF00046.24 KZN91778.1 - 2.8e-14 52.4 3.0 6e-14 51.4 2.1 1.6 1 0 0 1 1 1 1 Homeobox domain Amino_oxidase PF01593.19 KZN91779.1 - 1.5e-48 166.0 0.5 6.7e-48 163.8 0.3 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN91779.1 - 1.1e-15 57.3 0.3 2.9e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN91779.1 - 3.4e-06 27.3 0.2 8.3e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN91779.1 - 2.1e-05 23.6 0.3 0.00016 20.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN91779.1 - 3.9e-05 23.8 1.8 0.00037 20.6 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN91779.1 - 0.00051 19.2 0.2 0.00088 18.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KZN91779.1 - 0.0008 19.2 1.2 0.33 10.6 0.4 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 KZN91779.1 - 0.0014 17.2 0.8 0.0018 16.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN91779.1 - 0.0017 17.2 0.1 0.0026 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN91779.1 - 0.0027 17.6 0.9 0.17 11.7 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN91779.1 - 0.006 15.6 0.4 0.01 14.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KZN91779.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN91779.1 - 0.08 12.5 0.5 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2235 PF09994.4 KZN91781.1 - 4.5e-111 370.6 4.2 8.2e-111 369.8 2.9 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 KZN91782.1 - 4.3e-95 319.1 0.0 8.5e-93 311.5 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KZN91782.1 - 4.2e-06 25.5 0.1 0.00024 19.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 HTH_Tnp_Tc5 PF03221.11 KZN91783.1 - 3.1e-11 42.8 0.1 9.6e-11 41.3 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Phage_CP76 PF06892.6 KZN91783.1 - 0.018 14.3 0.3 0.04 13.2 0.1 1.7 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) Sigma70_r4 PF04545.11 KZN91783.1 - 0.066 12.5 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF972 PF06156.8 KZN91783.1 - 1.5 9.1 6.8 4.8 7.5 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Hexapep PF00132.19 KZN91784.1 - 5.4e-07 28.8 8.8 0.015 14.7 0.5 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KZN91784.1 - 0.00011 21.7 0.3 0.00011 21.7 0.2 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Glycos_transf_1 PF00534.15 KZN91785.1 - 4.9e-18 65.1 0.0 9.4e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KZN91785.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KZN91785.1 - 9.7e-06 25.7 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arf PF00025.16 KZN91786.1 - 3.6e-71 238.0 0.1 4.1e-71 237.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KZN91786.1 - 2.5e-13 49.7 0.0 2.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KZN91786.1 - 2.3e-12 46.3 1.4 5.8e-09 35.1 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KZN91786.1 - 4.2e-12 45.6 0.0 5.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KZN91786.1 - 4.7e-10 38.9 0.0 5.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN91786.1 - 2.9e-07 31.0 0.0 4.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KZN91786.1 - 7e-05 22.3 0.0 0.00014 21.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KZN91786.1 - 8.7e-05 22.4 0.1 0.00017 21.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KZN91786.1 - 0.014 14.4 0.2 0.023 13.7 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 KZN91786.1 - 0.015 14.5 0.4 0.029 13.6 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2945 PF11160.3 KZN91787.1 - 7.1e-09 35.3 0.0 3.2e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) Meth_synt_2 PF01717.13 KZN91789.1 - 3.3e-14 52.5 0.0 3.5e-09 36.1 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KZN91789.1 - 0.00087 18.6 0.0 0.014 14.6 0.0 2.6 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain F-box PF00646.28 KZN91790.1 - 0.16 11.6 3.5 1.9 8.2 0.2 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KZN91790.1 - 2 8.2 8.7 0.51 10.1 2.0 2.9 3 1 0 3 3 3 0 F-box-like PHD PF00628.24 KZN91792.1 - 7.1e-11 41.6 7.1 7.1e-11 41.6 4.9 2.4 2 0 0 2 2 2 1 PHD-finger APH PF01636.18 KZN91792.1 - 0.00071 19.3 0.1 0.0093 15.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family CDC27 PF09507.5 KZN91792.1 - 1.6 7.8 20.7 3.2 6.8 14.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TPR_10 PF13374.1 KZN91793.1 - 4.7e-63 207.4 0.1 7.9e-11 41.5 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KZN91793.1 - 1.2e-52 175.7 4.9 5.7e-14 51.8 0.0 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KZN91793.1 - 2.9e-20 70.3 6.4 0.00051 19.6 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN91793.1 - 4.9e-15 54.1 0.1 0.041 13.7 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN91793.1 - 9.5e-14 50.8 0.1 0.00055 19.5 0.0 4.5 3 1 0 5 5 4 3 TPR repeat TPR_1 PF00515.23 KZN91793.1 - 3.1e-13 48.7 0.0 0.22 11.2 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN91793.1 - 9.2e-13 47.6 7.7 0.61 10.8 0.0 8.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KZN91793.1 - 3.3e-12 45.5 0.3 1.7 9.0 0.0 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN91793.1 - 1.1e-11 45.1 0.0 0.0098 16.5 0.0 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KZN91793.1 - 6.3e-11 41.6 21.6 0.19 12.2 0.0 6.7 8 0 0 8 8 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KZN91793.1 - 9.3e-10 38.7 4.4 0.13 12.6 0.0 6.4 3 1 5 8 8 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 KZN91793.1 - 1.4e-08 34.5 0.3 0.33 11.4 0.0 6.1 8 0 0 8 8 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 KZN91793.1 - 2.8e-08 32.9 0.2 0.0031 16.4 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain TPR_8 PF13181.1 KZN91793.1 - 3.4e-08 32.6 0.0 2.6 8.0 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_5 PF12688.2 KZN91793.1 - 2.5e-07 30.7 3.3 0.01 15.8 0.1 4.3 1 1 3 4 4 4 2 Tetratrico peptide repeat Apc3 PF12895.2 KZN91793.1 - 2.9e-07 30.5 0.0 0.032 14.3 0.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 KZN91793.1 - 0.00031 20.7 0.2 3.5 8.1 0.0 4.7 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 KZN91793.1 - 0.00043 20.0 0.6 2.9 8.0 0.0 5.2 5 0 0 5 5 5 1 PPR repeat AAA_22 PF13401.1 KZN91793.1 - 0.013 15.6 0.0 0.068 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KZN91793.1 - 0.016 15.1 6.5 0.047 13.6 1.5 3.6 2 1 0 2 2 2 0 AAA ATPase domain 14-3-3 PF00244.15 KZN91793.1 - 0.048 12.7 0.2 9.6 5.1 0.0 2.9 1 1 0 3 3 3 0 14-3-3 protein Arch_ATPase PF01637.13 KZN91793.1 - 0.054 13.1 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase TPR_3 PF07720.7 KZN91793.1 - 0.096 12.5 0.0 96 2.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat THP2 PF09432.5 KZN91794.1 - 0.03 14.1 0.7 1.2 8.9 0.1 2.6 2 1 0 2 2 2 0 Tho complex subunit THP2 Sigma70_r2 PF04542.9 KZN91795.1 - 0.021 14.4 0.4 0.53 9.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-70 region 2 AMP-binding PF00501.23 KZN91796.1 - 1.3e-80 270.8 0.1 3e-80 269.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KZN91796.1 - 6.2e-61 205.4 0.0 1.8e-60 203.9 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KZN91796.1 - 2.4e-32 112.1 10.1 2.9e-30 105.3 3.9 2.9 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KZN91796.1 - 1.5e-18 67.1 5.9 1.2e-15 57.5 3.1 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KZN91796.1 - 3.4e-16 59.7 0.2 7.4e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN91796.1 - 2.2e-15 56.7 0.0 1.1e-08 34.8 0.0 3.1 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN91796.1 - 1.5e-11 44.3 0.0 3.8e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN91796.1 - 8.8e-10 37.7 0.1 0.00016 20.5 0.0 3.2 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KZN91796.1 - 2.3e-07 31.6 0.0 2.5e-06 28.3 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KZN91796.1 - 2.9e-06 26.3 1.6 4.6e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN91796.1 - 0.0012 18.8 2.7 0.01 15.8 0.8 3.1 3 1 0 3 3 3 1 NADH(P)-binding DFP PF04127.10 KZN91796.1 - 0.0024 17.5 1.1 0.0087 15.6 0.9 1.8 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 KZN91796.1 - 0.0085 15.8 1.1 0.021 14.5 0.8 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KZN91796.1 - 0.01 14.7 0.4 6.8 5.4 0.1 3.3 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein ApbA PF02558.11 KZN91796.1 - 0.014 14.7 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 KZN91796.1 - 0.32 10.2 2.5 0.9 8.7 0.9 2.3 4 0 0 4 4 4 0 NmrA-like family Sugar_tr PF00083.19 KZN91797.1 - 2.1e-99 333.1 24.4 2.4e-99 332.9 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91797.1 - 1.5e-26 93.0 42.3 7.4e-26 90.6 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN91798.1 - 1.6e-30 105.8 0.0 2.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91798.1 - 9.4e-11 41.4 12.9 1.7e-10 40.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KZN91798.1 - 0.018 14.9 0.4 0.086 12.7 0.1 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain 2OG-FeII_Oxy PF03171.15 KZN91799.1 - 1.2e-05 25.4 0.0 4.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KZN91799.1 - 3.1e-05 24.3 0.0 5.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KZN91799.1 - 4e-05 23.1 0.5 8.5e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2H2 PF00096.21 KZN91800.1 - 1.7e-06 27.9 14.5 2.7e-05 24.2 1.9 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN91800.1 - 6.7e-06 26.1 7.0 1.8e-05 24.8 2.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN91800.1 - 0.0014 18.7 0.7 0.0014 18.7 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN91800.1 - 0.0031 17.5 0.7 0.0031 17.5 0.5 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KZN91800.1 - 0.13 12.6 4.6 0.41 11.0 1.5 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 KZN91800.1 - 2.5 8.2 8.0 5.9 7.0 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fork_head PF00250.13 KZN91801.1 - 5.2e-38 128.9 1.5 1e-37 128.0 1.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KZN91801.1 - 2.5e-08 33.8 0.0 6.5e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain TENA_THI-4 PF03070.11 KZN91802.1 - 8.8e-17 61.5 0.0 7.5e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family PHD PF00628.24 KZN91805.1 - 3.5e-09 36.2 10.4 6.7e-09 35.3 7.2 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KZN91805.1 - 2.5e-05 24.4 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding AAA_17 PF13207.1 KZN91805.1 - 0.036 14.8 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-HC5HC2H PF13771.1 KZN91805.1 - 0.095 12.8 1.6 0.19 11.8 1.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 KZN91805.1 - 0.42 10.6 6.4 0.85 9.6 4.4 1.5 1 0 0 1 1 1 0 RING-like domain GFO_IDH_MocA PF01408.17 KZN91807.1 - 7.6e-11 42.5 0.1 2e-10 41.2 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 KZN91808.1 - 1e-33 116.1 0.0 6.3e-27 93.9 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family His_Phos_1 PF00300.17 KZN91809.1 - 5.1e-21 75.4 0.0 6e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3530 PF12048.3 KZN91809.1 - 0.0023 16.9 0.0 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) ADH_N PF08240.7 KZN91811.1 - 2.2e-26 91.7 4.1 3.8e-26 90.9 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN91811.1 - 1.8e-15 56.5 0.0 4.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KZN91811.1 - 0.00029 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 KZN91811.1 - 0.6 9.3 5.8 0.13 11.3 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region WD40 PF00400.27 KZN91812.1 - 1.3e-43 145.3 7.6 7.3e-08 32.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KZN91812.1 - 4.3e-09 35.9 0.1 9.5e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 KZN91812.1 - 0.00055 19.4 0.1 0.0085 15.5 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 KZN91812.1 - 0.0016 17.8 0.0 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat Nup160 PF11715.3 KZN91812.1 - 0.0081 14.3 0.2 0.68 7.9 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 F-box PF00646.28 KZN91812.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain EB1 PF03271.12 KZN91813.1 - 2.5e-16 59.4 0.5 4e-16 58.7 0.3 1.3 1 0 0 1 1 1 1 EB1-like C-terminal motif E1-E2_ATPase PF00122.15 KZN91814.1 - 1.1e-52 178.3 0.8 3.6e-52 176.6 0.0 2.2 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN91814.1 - 8.8e-46 155.7 9.5 2.3e-45 154.3 6.6 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN91814.1 - 3.2e-27 96.3 0.0 1.4e-26 94.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN91814.1 - 4.2e-16 58.6 0.0 8.6e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN91814.1 - 6.5e-15 55.7 0.0 1.7e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN91814.1 - 1.1e-07 31.1 0.1 4.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN91814.1 - 1e-05 25.2 0.0 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KZN91814.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) P16-Arc PF04699.9 KZN91815.1 - 1.1e-58 197.5 0.0 1.3e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.7 KZN91816.1 - 1.3e-11 44.8 0.0 3.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN91816.1 - 5.8e-08 32.6 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN91816.1 - 5.4e-07 30.0 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN91816.1 - 9.3e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN91816.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.8 KZN91817.1 - 1.2e-189 631.1 0.0 1.5e-189 630.8 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.4 KZN91817.1 - 0.54 9.3 5.9 0.97 8.5 0.8 2.7 2 0 0 2 2 2 0 Mu-like prophage protein Com Trm112p PF03966.11 KZN91817.1 - 4.5 7.7 6.7 17 5.8 0.2 3.3 3 0 0 3 3 3 0 Trm112p-like protein Ribosomal_S7e PF01251.13 KZN91818.1 - 3.9e-84 280.8 0.1 4.3e-84 280.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.17 KZN91819.1 - 1.1e-56 190.7 0.0 1.9e-56 189.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN91819.1 - 1.4e-20 74.0 0.0 2.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN91819.1 - 2.5e-14 52.8 0.0 4.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN91819.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN91819.1 - 2.4e-06 26.8 0.0 2.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN91819.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KZN91819.1 - 0.0055 16.7 0.0 0.0087 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN91819.1 - 0.076 13.1 0.1 0.21 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain Acetate_kinase PF00871.12 KZN91820.1 - 1.3e-93 313.6 0.0 1.6e-93 313.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 KZN91820.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) XFP_N PF09364.5 KZN91821.1 - 1.3e-154 514.4 0.0 1.7e-154 513.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KZN91821.1 - 5.3e-68 228.4 0.0 8.3e-68 227.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KZN91821.1 - 6.9e-67 224.4 0.0 1.1e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 KZN91821.1 - 0.0026 17.3 0.1 0.0067 16.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RTA1 PF04479.8 KZN91824.1 - 9.9e-56 188.7 9.3 1.4e-55 188.2 6.5 1.1 1 0 0 1 1 1 1 RTA1 like protein AAA_16 PF13191.1 KZN91827.1 - 0.00013 21.9 0.8 0.0048 16.9 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KZN91827.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KZN91827.1 - 0.087 12.5 0.1 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN91827.1 - 0.12 12.5 0.1 0.95 9.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain CLU PF13236.1 KZN91828.1 - 1.5e-80 269.8 0.0 3.3e-80 268.6 0.0 1.6 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 KZN91828.1 - 1.9e-53 180.8 0.0 4.8e-53 179.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KZN91828.1 - 6.4e-30 102.9 14.4 6.7e-11 41.9 0.1 4.2 2 1 3 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.1 KZN91828.1 - 4.5e-27 94.0 0.2 1.4e-26 92.4 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 KZN91828.1 - 2.1e-17 62.3 0.1 4.3e-06 26.4 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KZN91828.1 - 7e-06 25.5 2.7 0.36 10.8 0.1 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KZN91828.1 - 1.2e-05 24.8 3.1 0.081 12.5 0.3 3.5 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.1 KZN91828.1 - 0.0067 17.0 0.0 4.4 8.0 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat EnY2 PF10163.4 KZN91828.1 - 0.035 14.0 0.2 0.45 10.4 0.0 2.8 3 0 0 3 3 3 0 Transcription factor e(y)2 TPR_8 PF13181.1 KZN91828.1 - 0.038 13.7 2.9 1.1 9.1 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KZN91828.1 - 0.3 11.3 2.7 1.1e+02 3.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Aft1_HRR PF11787.3 KZN91829.1 - 0.13 13.3 0.4 0.13 13.3 0.3 2.4 2 0 0 2 2 2 0 Aft1 HRR domain NAD_binding_6 PF08030.7 KZN91830.1 - 3.8e-19 69.1 0.0 7.6e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KZN91830.1 - 2.7e-15 56.1 0.0 5.9e-14 51.8 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KZN91830.1 - 2.9e-14 53.2 11.4 2.9e-14 53.2 7.9 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KZN91830.1 - 8.8 6.5 14.5 4.6 7.4 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Tannase PF07519.6 KZN91831.1 - 2.1e-54 185.0 3.1 1.2e-33 116.6 0.0 3.0 2 1 1 3 3 3 3 Tannase and feruloyl esterase RTA1 PF04479.8 KZN91831.1 - 3.3e-08 33.3 2.5 0.00021 20.8 0.2 2.3 1 1 1 2 2 2 2 RTA1 like protein Peptidase_S9 PF00326.16 KZN91831.1 - 0.057 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family GST_N_3 PF13417.1 KZN91832.1 - 3.9e-14 52.6 0.0 7.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN91832.1 - 7.4e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN91832.1 - 7.2e-12 45.3 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN91832.1 - 1.9e-09 37.3 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KZN91832.1 - 3.3e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN91832.1 - 3.5e-07 30.6 0.0 7.6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 KZN91833.1 - 1.4e-11 43.7 9.7 1.8e-05 24.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KZN91833.1 - 8.1e-07 28.6 5.3 0.0006 19.4 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KZN91833.1 - 0.00055 19.5 0.2 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KZN91833.1 - 0.00081 19.0 6.1 0.36 10.5 0.4 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KZN91833.1 - 0.0011 18.5 6.0 0.29 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle HCO3_cotransp PF00955.16 KZN91834.1 - 4.2e-61 207.1 13.8 8e-42 143.5 2.9 2.7 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.24 KZN91835.1 - 7.1e-41 139.5 0.0 1.1e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN91835.1 - 1.5e-26 92.0 0.1 4e-26 90.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KZN91835.1 - 7.6e-05 21.6 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KZN91835.1 - 0.00028 20.7 0.0 0.00092 19.0 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1793 PF08760.6 KZN91837.1 - 1.3e-72 243.2 1.7 1.4e-72 243.0 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Stm1_N PF09598.5 KZN91838.1 - 2.2e-16 60.3 3.9 2.2e-16 60.3 2.7 5.5 3 1 1 4 4 4 1 Stm1 HSP9_HSP12 PF04119.7 KZN91838.1 - 9.7 6.3 7.6 11 6.1 0.2 2.9 3 0 0 3 3 3 0 Heat shock protein 9/12 NAD_binding_10 PF13460.1 KZN91839.1 - 8e-17 61.8 0.2 1.2e-16 61.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN91839.1 - 5.9e-12 45.5 0.5 2.9e-11 43.2 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KZN91839.1 - 1.1e-09 37.9 0.3 1.7e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KZN91839.1 - 2.9e-08 32.9 0.1 7.9e-08 31.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KZN91839.1 - 3.2e-06 26.0 0.1 9e-05 21.3 0.1 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN91839.1 - 7.5e-06 25.0 0.1 7.2e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.13 KZN91839.1 - 8.6e-06 25.7 0.1 4.4e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 TrkA-N domain adh_short PF00106.20 KZN91839.1 - 9.9e-05 22.3 0.3 0.00022 21.1 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KZN91839.1 - 0.00037 19.5 0.1 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KZN91839.1 - 0.026 14.4 0.5 0.064 13.1 0.2 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KZN91839.1 - 0.04 14.3 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent bZIP_1 PF00170.16 KZN91840.1 - 0.00016 21.5 10.3 0.00027 20.8 6.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KZN91840.1 - 0.025 14.3 9.9 0.025 14.3 6.9 2.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 KZN91840.1 - 0.031 13.2 3.1 1.3 7.9 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 KZN91840.1 - 0.12 12.5 1.8 0.18 11.8 1.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GvpL_GvpF PF06386.6 KZN91840.1 - 0.52 9.8 4.0 0.83 9.1 2.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pex19 PF04614.7 KZN91841.1 - 1.3e-69 234.6 9.4 2.9e-69 233.4 6.5 1.6 1 1 0 1 1 1 1 Pex19 protein family EspB PF05802.6 KZN91841.1 - 0.47 9.3 6.9 0.69 8.8 4.8 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF1631 PF07793.6 KZN91841.1 - 9.5 4.2 9.3 1.2 7.1 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1631) Mid2 PF04478.7 KZN91844.1 - 8.6e-10 38.2 1.1 8.6e-10 38.2 0.8 2.9 1 1 3 4 4 4 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.5 KZN91844.1 - 0.065 11.6 8.9 0.075 11.4 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SKG6 PF08693.5 KZN91844.1 - 0.071 12.4 1.3 0.33 10.2 0.9 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CRA PF06589.6 KZN91844.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.9 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Mitofilin PF09731.4 KZN91844.1 - 5.5 5.5 8.6 7.1 5.1 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2697 PF10906.3 KZN91846.1 - 1.3e-05 25.1 0.1 1.7e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) Fungal_trans_2 PF11951.3 KZN91847.1 - 1.3e-31 109.5 0.2 4.5e-31 107.8 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91847.1 - 1.4e-06 28.1 8.0 2.6e-06 27.2 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KZN91848.1 - 6.9e-66 222.0 0.0 9.3e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN91848.1 - 1.3e-31 109.6 0.0 2.9e-31 108.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN91848.1 - 4.6e-05 22.5 0.0 8.7e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN91848.1 - 0.0003 19.8 0.0 0.00063 18.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KZN91848.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN91848.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 RIO1 family APC_CDC26 PF10471.4 KZN91849.1 - 0.017 15.8 0.2 0.081 13.6 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 NAD_binding_8 PF13450.1 KZN91850.1 - 2.1e-09 37.2 0.0 5.6e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN91850.1 - 3.9e-05 23.7 0.2 0.00016 21.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KZN91850.1 - 0.00029 20.0 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KZN91850.1 - 0.0051 15.9 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KZN91850.1 - 0.0081 16.0 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN91850.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KZN91850.1 - 0.034 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN91850.1 - 0.04 12.3 0.0 0.06 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 KZN91850.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 KZN91850.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN91850.1 - 0.14 11.0 0.1 0.28 10.0 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.11 KZN91851.1 - 2.7e-26 92.0 15.6 2.7e-26 92.0 10.8 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KZN91851.1 - 5.7e-06 25.4 24.4 4.5e-05 22.5 16.9 2.0 1 1 0 1 1 1 1 UAA transporter family TFIIB PF00382.14 KZN91854.1 - 3.2e-32 110.1 0.3 1.6e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KZN91854.1 - 1.3e-24 86.2 1.8 2.9e-24 85.1 0.0 2.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KZN91854.1 - 4.2e-06 26.3 0.0 0.037 13.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KZN91854.1 - 0.00027 20.1 2.8 0.00074 18.7 1.9 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 KZN91854.1 - 0.11 12.3 0.9 0.21 11.4 0.6 1.4 1 0 0 1 1 1 0 IBR domain E1-E2_ATPase PF00122.15 KZN91855.1 - 1.3e-52 178.0 0.1 1.9e-51 174.2 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KZN91855.1 - 5.3e-42 141.8 2.7 2.6e-13 49.8 0.0 5.2 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.21 KZN91855.1 - 7.5e-39 134.3 0.1 1.6e-38 133.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN91855.1 - 2.4e-17 63.7 0.0 4.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN91855.1 - 4.4e-07 29.7 0.1 0.001 18.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ERCC4 PF02732.10 KZN91856.1 - 1.5e-30 105.8 0.0 3e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KZN91856.1 - 0.0041 17.2 0.0 0.0088 16.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Epimerase PF01370.16 KZN91858.1 - 3.3e-20 72.5 0.0 4.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN91858.1 - 1.1e-10 40.7 0.0 1.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KZN91858.1 - 9.2e-08 31.3 0.0 0.002 17.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 KZN91858.1 - 1.9e-07 31.1 0.0 1.2e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KZN91858.1 - 2.4e-07 30.9 0.0 3.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KZN91858.1 - 3.2e-06 26.2 0.0 1.5e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KZN91858.1 - 0.00031 20.4 0.0 0.093 12.3 0.0 2.5 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 KZN91858.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KZN91858.1 - 0.046 12.6 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KZN91858.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.13 KZN91859.1 - 1.7e-08 33.7 0.5 4.2e-08 32.3 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91859.1 - 2.7e-06 27.2 10.8 4.4e-06 26.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ChAPs PF09295.5 KZN91861.1 - 2e-158 527.2 0.0 2.6e-158 526.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 KZN91861.1 - 1.3e-06 27.9 0.1 0.013 15.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KZN91861.1 - 5e-05 22.7 0.0 3.7 7.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN91861.1 - 0.00012 21.5 0.0 6 6.8 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KZN91861.1 - 0.00022 20.8 0.4 0.43 10.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KZN91861.1 - 0.0011 18.8 0.7 9 6.3 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KZN91861.1 - 0.0016 17.5 1.1 0.16 11.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN91861.1 - 0.0017 18.6 0.2 1.2 9.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN91861.1 - 0.0022 17.6 0.5 24 5.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN91861.1 - 0.0041 17.6 5.9 1.9 9.3 0.0 4.7 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN91861.1 - 0.0058 17.2 0.0 2.3 8.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN91861.1 - 0.014 15.2 0.1 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KZN91861.1 - 0.018 15.1 0.2 1.2 9.3 0.0 3.1 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KZN91862.1 - 0.00018 21.0 1.3 0.033 13.8 0.4 3.9 4 0 0 4 4 4 2 TPR repeat Kinesin PF00225.18 KZN91863.1 - 3.3e-59 200.2 0.0 4.9e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 KZN91863.1 - 0.0023 17.7 2.0 0.0056 16.4 1.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper KIAA1430 PF13879.1 KZN91863.1 - 0.049 14.0 1.0 0.11 12.9 0.7 1.5 1 0 0 1 1 1 0 KIAA1430 homologue DUF837 PF05769.6 KZN91863.1 - 0.14 11.6 3.1 0.24 10.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) AAA_33 PF13671.1 KZN91863.1 - 0.44 10.4 3.2 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KZN91863.1 - 5.6 6.7 5.2 5.2 6.8 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 RTA1 PF04479.8 KZN91864.1 - 0.1 12.0 4.5 0.15 11.4 3.2 1.3 1 1 0 1 1 1 0 RTA1 like protein MFS_1 PF07690.11 KZN91865.1 - 1.7e-31 109.2 38.4 1.1e-30 106.5 26.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91865.1 - 4.9e-11 41.8 29.8 1.3e-10 40.4 20.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KZN91865.1 - 0.00032 19.2 6.2 0.00032 19.2 4.3 3.4 1 1 2 3 3 3 1 MFS/sugar transport protein Peptidase_S24 PF00717.18 KZN91866.1 - 2.7e-05 23.7 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Sarcolipin PF05366.6 KZN91866.1 - 0.12 11.8 0.2 0.39 10.1 0.2 1.8 1 0 0 1 1 1 0 Sarcolipin UQ_con PF00179.21 KZN91867.1 - 5.1e-41 139.3 0.0 5.8e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN91867.1 - 1.1e-06 28.3 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KZN91867.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 KZN91867.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain F_bP_aldolase PF01116.15 KZN91871.1 - 1.5e-98 329.4 0.0 1.7e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.24 KZN91872.1 - 1.9e-43 148.5 0.0 4.5e-37 127.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN91872.1 - 2.1e-15 56.9 0.1 9.6e-15 54.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Multi-haem_cyto PF13447.1 KZN91872.1 - 4 6.4 5.2 0.54 9.2 0.1 2.0 2 0 0 2 2 2 0 Seven times multi-haem cytochrome CxxCH AlaDh_PNT_N PF05222.10 KZN91873.1 - 9.2e-30 103.4 0.0 1.5e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KZN91873.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF739 PF05339.6 KZN91875.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF739) CUE PF02845.11 KZN91876.1 - 1.6e-08 33.8 0.0 2.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 KZN91876.1 - 0.25 11.0 4.5 0.11 12.1 0.3 2.7 3 0 0 3 3 3 0 Ubiquitin-associated protein 2 MFS_1 PF07690.11 KZN91878.1 - 3.5e-40 137.7 42.2 6.3e-39 133.6 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91878.1 - 4.4e-07 28.8 14.3 4.4e-07 28.8 9.9 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 KZN91879.1 - 8.5e-112 374.0 19.6 9.8e-112 373.8 13.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KZN91879.1 - 3.9e-06 25.8 6.8 3.9e-06 25.8 4.7 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX16 PF14138.1 KZN91879.1 - 0.035 14.2 1.0 4.6 7.4 0.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 DUF4381 PF14316.1 KZN91879.1 - 0.58 10.2 2.2 0.56 10.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Glyco_hydro_3 PF00933.16 KZN91880.1 - 2.1e-65 220.6 0.0 2.9e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 KZN91880.1 - 4.3e-17 61.9 0.0 3.3e-08 33.4 0.0 3.1 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN91880.1 - 3.9e-14 52.5 0.0 4.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN91880.1 - 1.4e-09 38.0 0.0 1.6e-06 28.2 0.0 2.9 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN91880.1 - 4.3e-05 23.3 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 KZN91880.1 - 0.0005 20.0 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 KZN91880.1 - 0.0041 16.6 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain FR47 PF08445.5 KZN91880.1 - 0.02 14.6 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein GST_N_3 PF13417.1 KZN91881.1 - 1.2e-13 51.0 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN91881.1 - 4e-12 46.1 0.0 1.1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KZN91881.1 - 8.4e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KZN91881.1 - 1.8e-09 37.4 0.0 3.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KZN91881.1 - 5.8e-08 32.5 0.0 1.8e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN91881.1 - 2.5e-05 24.6 0.0 3.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Saccharop_dh PF03435.13 KZN91882.1 - 2.4e-81 273.6 0.0 1.2e-48 166.0 0.0 2.0 1 1 1 2 2 2 2 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN91882.1 - 2e-07 31.2 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KZN91882.1 - 0.0015 18.8 0.1 0.004 17.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KZN91882.1 - 0.0027 17.7 0.3 0.0042 17.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KZN91882.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KZN91882.1 - 0.094 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.19 KZN91883.1 - 3.3e-86 289.6 25.5 4.2e-86 289.3 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN91883.1 - 1.9e-17 63.0 64.9 9.5e-15 54.1 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ashwin PF15323.1 KZN91884.1 - 0.037 14.0 0.3 0.089 12.7 0.2 1.7 1 0 0 1 1 1 0 Developmental protein Cwf_Cwc_15 PF04889.7 KZN91884.1 - 3.8 7.1 18.6 2 8.0 2.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNase_T PF00929.19 KZN91885.1 - 8.4e-26 91.2 0.0 9.5e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 KZN91886.1 - 6.5e-32 109.8 0.0 9.6e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KZN91886.1 - 2.5e-25 88.7 0.0 4.3e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KZN91886.1 - 8.6e-17 61.3 0.0 2.2e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KZN91886.1 - 4.2e-09 36.2 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 KZN91887.1 - 1.7e-11 44.6 0.0 5.4e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN91887.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain K_oxygenase PF13434.1 KZN91888.1 - 1.9e-16 59.9 0.0 1.5e-10 40.5 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KZN91888.1 - 2e-12 47.6 0.0 3.9e-05 23.8 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN91888.1 - 7.3e-07 29.0 0.0 0.041 13.6 0.0 3.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KZN91888.1 - 0.00021 21.3 0.0 0.14 12.3 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KZN91888.1 - 0.00076 18.4 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KZN91888.1 - 0.00092 19.1 0.0 0.1 12.4 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN91888.1 - 0.0024 16.4 0.0 0.079 11.4 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN91888.1 - 0.0026 16.6 0.0 0.024 13.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KZN91888.1 - 0.003 16.4 0.4 0.22 10.3 0.0 2.4 2 1 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 KZN91888.1 - 0.0043 16.1 0.0 0.04 13.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KZN91888.1 - 0.0076 16.2 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KZN91888.1 - 0.015 14.3 0.3 0.058 12.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 KZN91888.1 - 0.016 14.1 0.1 0.86 8.4 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase HMG_CoA_synt_C PF08540.5 KZN91890.1 - 7.3e-103 343.9 0.5 9e-103 343.6 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KZN91890.1 - 1e-93 311.6 0.3 1.7e-93 310.9 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TFR_dimer PF04253.10 KZN91891.1 - 1.2e-31 108.8 0.1 2.4e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KZN91891.1 - 2.2e-15 56.8 0.0 4.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KZN91891.1 - 3.8e-06 26.5 0.0 7.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KZN91891.1 - 0.00029 20.4 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans PF04082.13 KZN91892.1 - 6e-06 25.3 0.1 1.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91892.1 - 0.00012 21.9 8.4 0.00012 21.9 5.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPP_enzyme_N PF02776.13 KZN91893.1 - 5.9e-36 123.5 0.0 9.8e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN91893.1 - 8.8e-19 67.6 0.0 2.2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KZN91893.1 - 2.8e-15 56.1 0.2 9.2e-14 51.2 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1765 PF08578.5 KZN91894.1 - 6.5e-46 155.4 4.6 6.5e-46 155.4 3.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 KZN91895.1 - 3.7e-26 90.6 1.5 5.4e-26 90.0 1.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KZN91895.1 - 0.00014 21.6 0.1 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 DOR PF14839.1 KZN91895.1 - 0.066 12.9 2.3 0.095 12.4 0.4 1.8 1 1 1 2 2 2 0 DOR family DUF3070 PF11270.3 KZN91895.1 - 2.6 7.9 6.5 0.29 10.9 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) TFIIB PF00382.14 KZN91896.1 - 9.8e-40 134.2 0.2 6.3e-20 70.7 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KZN91896.1 - 1.9e-10 39.8 1.1 1.9e-10 39.8 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 KZN91896.1 - 0.001 18.6 0.1 0.75 9.3 0.0 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain HTH_23 PF13384.1 KZN91896.1 - 0.07 12.8 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DZR PF12773.2 KZN91896.1 - 0.11 12.3 1.3 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Sigma70_r4_2 PF08281.7 KZN91896.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1610 PF07754.6 KZN91896.1 - 0.54 10.4 3.3 2.9 8.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 KZN91896.1 - 3.5 6.9 5.7 0.54 9.5 1.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Mucin PF01456.12 KZN91897.1 - 0.15 11.8 4.9 0.18 11.5 3.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DIL PF01843.14 KZN91899.1 - 4.4e-18 65.1 1.5 4.2e-11 42.6 0.1 2.7 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KZN91899.1 - 8.5e-17 61.2 0.0 7.3e-16 58.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN91899.1 - 1.2e-12 47.6 0.0 2.4e-05 24.4 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KZN91899.1 - 2.4e-12 45.9 0.0 4e-05 23.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KZN91899.1 - 4.7e-08 33.3 0.0 0.0035 17.8 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN91899.1 - 2e-06 27.4 0.2 0.005 16.9 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat RasGEF PF00617.14 KZN91900.1 - 4.8e-45 153.6 0.4 7.2e-45 153.0 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KZN91900.1 - 2.4e-13 50.0 1.0 4.6e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M13_N PF05649.8 KZN91901.1 - 7.8e-91 305.0 0.0 1.1e-90 304.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KZN91901.1 - 8.8e-55 185.0 0.0 1.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 PhageMin_Tail PF10145.4 KZN91901.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.7 1 1 0 1 1 1 0 Phage-related minor tail protein RicinB_lectin_2 PF14200.1 KZN91902.1 - 0.014 15.7 0.0 0.099 13.0 0.0 2.3 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like FMN_dh PF01070.13 KZN91903.1 - 6.8e-108 360.6 0.0 8.5e-108 360.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KZN91903.1 - 2.4e-06 26.7 0.0 6.2e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 KZN91903.1 - 2.2e-05 23.5 0.2 4.5e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KZN91903.1 - 0.00089 18.5 0.2 0.16 11.2 0.0 2.5 2 1 1 3 3 3 2 Histidine biosynthesis protein NMO PF03060.10 KZN91903.1 - 0.055 12.6 0.3 0.1 11.7 0.1 1.4 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.9 KZN91903.1 - 0.12 11.4 0.0 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Peripla_BP_4 PF13407.1 KZN91903.1 - 0.16 11.2 0.0 1 8.6 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein domain MFS_1 PF07690.11 KZN91905.1 - 1.9e-18 66.3 21.5 1.9e-18 66.3 14.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 KZN91905.1 - 2.1 6.8 6.2 0.66 8.4 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) G-alpha PF00503.15 KZN91906.1 - 8.8e-115 383.4 0.1 1.1e-114 383.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KZN91906.1 - 3.5e-14 52.4 0.1 2.2e-09 36.7 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KZN91906.1 - 1.2e-06 27.8 0.2 0.0036 16.4 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN91906.1 - 0.0017 18.8 0.0 0.1 13.0 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KZN91906.1 - 0.0062 16.4 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF1967 PF09269.6 KZN91906.1 - 0.013 15.0 0.1 5 6.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) GTP_EFTU PF00009.22 KZN91906.1 - 0.032 13.6 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KZN91906.1 - 0.038 13.5 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 KZN91906.1 - 0.17 10.9 4.5 0.03 13.3 0.5 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF1713 PF08213.6 KZN91907.1 - 9.1e-13 47.5 19.9 9.1e-13 47.5 13.8 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KZN91907.1 - 0.017 15.0 0.6 0.045 13.6 0.0 2.2 2 1 0 2 2 2 0 Mitochondrial protein Pet20 Tox-GHH2 PF15635.1 KZN91907.1 - 0.041 14.2 0.4 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 ATP-synt_C PF00137.16 KZN91908.1 - 1.5e-24 85.6 18.2 7.6e-18 64.1 8.0 2.0 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.8 KZN91908.1 - 1.6 6.7 4.5 4 5.4 0.4 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2970 PF11174.3 KZN91908.1 - 5.7 6.6 9.0 1.5 8.4 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Pmp3 PF01679.12 KZN91910.1 - 1.6e-27 94.9 6.6 1.7e-27 94.8 4.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 KZN91910.1 - 0.088 12.8 0.7 0.11 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) CFEM PF05730.6 KZN91911.1 - 6.8e-05 22.6 7.2 0.00014 21.5 5.0 1.5 1 0 0 1 1 1 1 CFEM domain Ste5 PF11610.3 KZN91911.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.3 3 0 0 3 3 3 0 Scaffold protein Ste5-Fus5 binding region LRR_4 PF12799.2 KZN91912.1 - 0.0044 16.6 1.3 5.1 6.8 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Hydrolase_6 PF13344.1 KZN91913.1 - 7.6e-22 77.1 0.0 1.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN91913.1 - 2.6e-11 43.0 0.0 1e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Lipase_3 PF01764.20 KZN91913.1 - 0.016 14.7 0.1 0.046 13.3 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 3) HAD_2 PF13419.1 KZN91913.1 - 0.1 12.8 0.0 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN91913.1 - 0.1 12.9 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_2c PF01411.14 KZN91914.1 - 4.4e-11 41.7 0.0 5.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KZN91914.1 - 7.7e-09 35.3 0.8 1.7e-08 34.2 0.5 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF676 PF05057.9 KZN91915.1 - 1.4e-46 158.5 0.0 2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KZN91915.1 - 2.4e-05 23.9 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KZN91915.1 - 2.8e-05 24.1 0.0 9.9e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN91915.1 - 4.9e-05 23.1 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN91915.1 - 8.3e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF2235 PF09994.4 KZN91915.1 - 0.0016 17.8 0.1 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_2 PF01674.13 KZN91915.1 - 0.038 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DLH PF01738.13 KZN91915.1 - 0.082 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KZN91915.1 - 0.09 12.1 0.1 1.1 8.7 0.1 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase LCAT PF02450.10 KZN91915.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4551 PF15087.1 KZN91916.1 - 1 7.6 3.5 1.4 7.2 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_L22e PF01776.12 KZN91917.1 - 1.9e-50 169.5 0.4 2.3e-50 169.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DIM1 PF02966.11 KZN91918.1 - 1.4e-70 234.9 0.3 1.6e-70 234.7 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Translin PF01997.11 KZN91919.1 - 1.3e-51 175.1 0.1 1.5e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Translin family FRQ PF09421.5 KZN91919.1 - 0.0037 15.1 0.0 0.0065 14.3 0.0 1.3 2 0 0 2 2 2 1 Frequency clock protein GMP_synt_C PF00958.17 KZN91919.1 - 0.015 15.0 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain GSHPx PF00255.14 KZN91920.1 - 4.8e-38 128.8 0.0 6.9e-38 128.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KZN91920.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 KZN91920.1 - 0.06 12.8 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Redoxin Ral PF11058.3 KZN91920.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DSPn PF14671.1 KZN91922.1 - 5.5e-46 156.0 0.0 4.5e-42 143.3 0.0 3.2 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KZN91922.1 - 1.2e-16 60.4 0.0 1.7e-15 56.7 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KZN91922.1 - 3.7e-06 26.4 0.1 1.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase LptE PF04390.7 KZN91922.1 - 0.027 14.2 0.4 0.052 13.2 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Ku PF02735.11 KZN91923.1 - 7.9e-29 100.5 0.0 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KZN91923.1 - 4e-23 82.0 0.0 2.2e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KZN91923.1 - 9.4e-17 61.0 0.0 1.9e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.23 KZN91923.1 - 0.00082 19.1 1.5 0.0039 16.9 0.2 2.4 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF4149 PF13664.1 KZN91924.1 - 1.4e-24 86.0 4.6 1.9e-24 85.6 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DAO PF01266.19 KZN91925.1 - 7e-20 71.2 0.1 2e-19 69.7 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN91925.1 - 0.0023 18.2 0.8 0.0064 16.8 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN91925.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN91925.1 - 0.029 14.2 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN91925.1 - 0.043 12.8 0.3 0.067 12.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KZN91925.1 - 0.067 12.2 0.3 0.48 9.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 KZN91925.1 - 0.11 12.1 0.4 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 KZN91925.1 - 0.94 9.2 2.7 0.6 9.9 0.2 1.9 3 0 0 3 3 3 0 ThiF family DUF4613 PF15390.1 KZN91926.1 - 0.034 12.3 2.5 0.045 11.9 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF812 PF05667.6 KZN91926.1 - 0.1 11.0 3.0 0.14 10.6 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) MADF_DNA_bdg PF10545.4 KZN91926.1 - 1.3 9.2 6.5 0.31 11.2 0.5 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BNR_2 PF13088.1 KZN91927.1 - 1.2e-07 31.3 0.0 3.7e-07 29.7 0.0 1.8 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KZN91927.1 - 0.0014 18.1 8.4 0.083 12.7 0.1 4.1 4 0 0 4 4 4 2 BNR/Asp-box repeat ABC_tran PF00005.22 KZN91928.1 - 1.7e-47 161.1 0.1 1.4e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN91928.1 - 7.2e-16 58.4 29.3 9.5e-13 48.1 5.8 4.3 3 2 0 3 3 3 2 ABC transporter transmembrane region AAA_16 PF13191.1 KZN91928.1 - 3.1e-10 40.3 0.0 8.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KZN91928.1 - 2.1e-09 37.7 0.2 0.41 10.5 0.0 4.5 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KZN91928.1 - 1.3e-08 34.4 8.2 0.0033 16.6 1.7 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KZN91928.1 - 2.3e-08 33.4 1.4 0.0035 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KZN91928.1 - 5.9e-07 28.6 0.2 0.0054 15.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 KZN91928.1 - 1.6e-05 24.1 0.1 0.018 14.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KZN91928.1 - 4.1e-05 23.1 0.2 0.18 11.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 KZN91928.1 - 9.4e-05 22.8 0.2 0.4 10.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KZN91928.1 - 0.00012 22.8 0.4 0.86 10.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 KZN91928.1 - 0.0002 21.2 1.2 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KZN91928.1 - 0.00033 20.7 3.5 0.34 11.0 0.2 3.9 2 2 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 KZN91928.1 - 0.00058 18.5 0.5 0.05 12.2 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Miro PF08477.8 KZN91928.1 - 0.0013 19.1 0.7 1 9.8 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein NB-ARC PF00931.17 KZN91928.1 - 0.0014 17.5 0.0 0.046 12.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 KZN91928.1 - 0.0014 18.5 0.1 0.71 9.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KZN91928.1 - 0.0023 17.3 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KZN91928.1 - 0.0025 17.5 0.7 1.9 8.1 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KZN91928.1 - 0.0039 17.5 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KZN91928.1 - 0.0054 16.6 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 KZN91928.1 - 0.0057 15.6 0.1 0.32 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 KZN91928.1 - 0.0059 16.5 0.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KZN91928.1 - 0.0059 16.4 2.4 1.9 8.2 0.1 2.7 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.7 KZN91928.1 - 0.0087 15.1 1.3 1.2 8.1 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 KZN91928.1 - 0.011 15.2 2.6 0.37 10.1 0.2 2.7 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 KZN91928.1 - 0.016 14.8 0.3 1.5 8.4 0.0 3.3 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 KZN91928.1 - 0.017 15.2 0.4 15 5.8 0.0 3.4 4 0 0 4 4 3 0 RNA helicase ATP_bind_1 PF03029.12 KZN91928.1 - 0.024 14.2 0.4 3.4 7.1 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 KZN91928.1 - 0.12 11.8 0.6 3.9 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KZN91928.1 - 0.12 11.9 0.6 28 4.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KZN91928.1 - 0.29 10.1 0.3 1.2 8.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TyeA PF09059.5 KZN91930.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 TyeA CsgF PF10614.4 KZN91930.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein ADH_zinc_N_2 PF13602.1 KZN91931.1 - 7.1e-17 62.4 0.6 1.5e-16 61.4 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN91931.1 - 4e-11 42.5 2.4 7.7e-11 41.6 1.5 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KZN91931.1 - 0.00041 20.4 0.9 0.00063 19.7 0.6 1.4 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 KZN91931.1 - 0.00046 19.9 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KZN91931.1 - 0.084 12.4 0.4 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 KZN91931.1 - 0.18 11.7 1.3 0.28 11.0 0.9 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_3 PF00933.16 KZN91932.1 - 1.6e-94 316.3 0.0 3.8e-94 315.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN91932.1 - 5.8e-57 192.8 1.8 3.4e-56 190.3 1.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN91932.1 - 1e-16 60.6 0.1 2.2e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.16 KZN91933.1 - 0.00038 20.3 13.8 0.0021 18.0 9.5 2.1 1 1 1 2 2 2 1 bZIP transcription factor EcoR124_C PF12008.3 KZN91933.1 - 0.0043 16.2 2.6 0.0077 15.4 1.8 1.3 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal Dynactin PF12455.3 KZN91933.1 - 0.089 11.6 5.4 0.15 10.9 3.7 1.3 1 0 0 1 1 1 0 Dynein associated protein CCDC32 PF14989.1 KZN91933.1 - 0.1 12.4 3.1 0.17 11.6 2.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 EBP PF05241.7 KZN91934.1 - 5.8e-09 35.2 5.8 5.4e-08 32.0 4.0 2.1 1 1 0 1 1 1 1 Emopamil binding protein Fungal_trans PF04082.13 KZN91935.1 - 1.1e-24 86.6 0.0 1.9e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN91935.1 - 2.7e-09 36.8 11.9 4.2e-09 36.1 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain hDGE_amylase PF14701.1 KZN91935.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Man-6-P_recep PF02157.10 KZN91936.1 - 8.2e-12 44.7 0.1 1.1e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KZN91936.1 - 2.3e-10 40.3 0.1 6.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KZN91936.1 - 0.0004 19.6 0.1 0.00092 18.5 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 ERG4_ERG24 PF01222.12 KZN91937.1 - 8e-158 525.4 6.0 9e-158 525.3 4.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KZN91937.1 - 5.6e-05 22.5 0.1 0.00016 21.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-MYND PF01753.13 KZN91938.1 - 2.2e-11 43.4 9.4 4.5e-11 42.4 6.5 1.6 1 0 0 1 1 1 1 MYND finger Glyco_hydro_7 PF00840.15 KZN91938.1 - 0.048 12.0 0.0 0.084 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 SF3b10 PF07189.6 KZN91939.1 - 1.2e-36 124.3 0.0 1.3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.3 KZN91940.1 - 5.6e-62 208.6 0.1 5.6e-62 208.6 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) START PF01852.14 KZN91940.1 - 0.0013 18.0 0.2 0.25 10.6 0.0 2.7 3 0 0 3 3 3 2 START domain HALZ PF02183.13 KZN91940.1 - 0.11 12.2 8.0 0.11 12.2 1.0 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper ATG16 PF08614.6 KZN91940.1 - 0.79 9.5 29.5 1.2 8.9 10.0 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 KZN91940.1 - 1.8 8.5 6.1 9.4 6.2 0.4 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 KZN91940.1 - 2.1 8.3 24.5 0.82 9.7 6.9 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PRKCSH-like PF12999.2 KZN91942.1 - 0.045 13.3 1.6 0.056 13.0 1.1 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Phage_GP20 PF06810.6 KZN91942.1 - 0.12 11.8 11.1 0.17 11.3 7.7 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Nop25 PF09805.4 KZN91942.1 - 0.13 12.3 14.8 0.097 12.7 9.1 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) MxiH PF09392.5 KZN91942.1 - 0.15 12.6 2.2 0.23 12.0 1.5 1.3 1 0 0 1 1 1 0 Type III secretion needle MxiH like DUF3552 PF12072.3 KZN91942.1 - 0.23 10.6 14.7 0.31 10.2 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2951 PF11166.3 KZN91942.1 - 0.29 11.0 7.6 0.41 10.5 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) APG6 PF04111.7 KZN91942.1 - 1.2 8.1 11.0 1.5 7.8 7.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 BRE1 PF08647.6 KZN91942.1 - 1.2 9.1 15.8 2 8.4 11.0 1.3 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Peptidase_S49_N PF08496.5 KZN91942.1 - 1.2 8.9 9.4 1.5 8.6 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IncA PF04156.9 KZN91942.1 - 1.2 8.6 8.1 1.5 8.3 5.6 1.1 1 0 0 1 1 1 0 IncA protein DUF4163 PF13739.1 KZN91942.1 - 1.2 9.9 4.0 1.7 9.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) ADIP PF11559.3 KZN91942.1 - 1.5 8.7 11.4 2 8.3 7.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KZN91942.1 - 1.9 6.2 5.3 2.2 5.9 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 KZN91942.1 - 2.7 6.9 6.8 3 6.8 4.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein NT-C2 PF10358.4 KZN91943.1 - 1e-29 102.8 0.0 1.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 KZN91944.1 - 4e-51 173.4 0.0 8.2e-51 172.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Myotub-related PF06602.9 KZN91945.1 - 2.2e-123 411.5 0.0 3.2e-123 410.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KZN91945.1 - 0.079 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.15 KZN91946.1 - 7.7e-17 61.2 0.1 1.6e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KZN91946.1 - 3.6e-12 45.6 0.0 6.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KZN91946.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Glyco_transf_8 PF01501.15 KZN91947.1 - 4.8e-37 127.6 0.0 7.8e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KZN91947.1 - 0.00026 20.8 0.1 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Abhydrolase_6 PF12697.2 KZN91948.1 - 2.5e-20 73.3 0.3 1e-19 71.3 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN91948.1 - 4e-05 23.4 0.0 7.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN91948.1 - 8.9e-05 22.1 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Arb2 PF09757.4 KZN91948.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.5 2 0 0 2 2 2 0 Arb2 domain Aldolase PF01081.14 KZN91948.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Glyco_transf_90 PF05686.7 KZN91949.1 - 2.3e-17 62.7 12.2 1.3e-14 53.7 6.4 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ferric_reduct PF01794.14 KZN91950.1 - 8.3e-13 48.5 4.6 8.3e-13 48.5 3.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF2678 PF10856.3 KZN91950.1 - 0.066 12.9 1.4 0.17 11.6 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) Cytochrom_B_C PF00032.12 KZN91950.1 - 1.2 9.4 7.8 2.9 8.1 1.1 2.8 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD HEAT PF02985.17 KZN91951.1 - 2.9e-43 142.0 15.1 0.0028 17.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KZN91951.1 - 2.5e-34 117.4 0.5 6.5e-09 35.9 0.0 7.4 2 2 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KZN91951.1 - 4.2e-12 46.2 3.2 0.00056 20.2 0.0 7.3 5 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KZN91951.1 - 2.2e-10 40.6 9.6 0.012 16.0 0.0 8.7 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KZN91951.1 - 5.7e-07 28.2 10.7 0.0008 17.8 1.5 4.4 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 KZN91951.1 - 0.00056 19.3 2.0 3 7.1 0.0 4.5 3 2 1 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 KZN91951.1 - 0.0016 18.2 5.1 0.94 9.4 0.2 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KZN91951.1 - 0.016 14.2 0.2 0.3 10.0 0.1 2.7 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 KZN91951.1 - 0.018 14.8 5.0 1.6 8.5 0.2 4.3 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KZN91951.1 - 0.099 10.8 3.9 0.72 8.0 0.1 2.9 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.18 KZN91951.1 - 0.16 11.8 11.6 1.6 8.7 0.0 6.3 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat B3_4 PF03483.12 KZN91952.1 - 8.8e-25 87.1 0.0 2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KZN91952.1 - 4.1e-20 71.3 0.0 1.8e-16 59.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain CDO_I PF05995.7 KZN91953.1 - 1.7e-41 141.3 0.0 2.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KZN91953.1 - 5.3e-05 22.6 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) MMR_HSR1 PF01926.18 KZN91954.1 - 1.8e-20 73.0 0.1 4.4e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 KZN91954.1 - 4e-19 68.1 0.1 8.9e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KZN91954.1 - 5.6e-11 41.9 0.1 2.7e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KZN91954.1 - 1.1e-05 25.3 0.1 0.046 13.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KZN91954.1 - 3.4e-05 23.3 0.3 0.75 9.1 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KZN91954.1 - 0.0064 15.2 0.1 0.015 14.0 0.1 1.6 1 0 0 1 1 1 1 ArgK protein AIG1 PF04548.11 KZN91954.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KZN91954.1 - 0.018 15.5 0.0 0.057 13.9 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 KZN91954.1 - 0.029 13.6 0.2 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 KZN91954.1 - 0.069 12.5 0.0 0.86 8.9 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 KZN91954.1 - 0.1 11.8 0.3 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HTH_Tnp_Tc5 PF03221.11 KZN91955.1 - 9.2e-14 51.0 0.0 1.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KZN91955.1 - 3.8e-05 23.0 0.1 7.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KZN91955.1 - 0.0025 17.3 0.1 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 KZN91955.1 - 0.0099 15.5 0.2 0.065 12.9 0.0 2.4 3 0 0 3 3 3 1 MarR family HTH_Tnp_4 PF13613.1 KZN91955.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.5 KZN91955.1 - 0.036 13.6 0.0 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_10 PF04967.7 KZN91955.1 - 0.079 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.1 KZN91955.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PXA PF02194.10 KZN91956.1 - 1.5e-41 141.9 0.0 2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 PXA domain FAM209 PF15206.1 KZN91956.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 FAM209 family Kinocilin PF15033.1 KZN91956.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinocilin protein IU_nuc_hydro PF01156.14 KZN91957.1 - 7.6e-47 160.0 0.0 8.9e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.4 KZN91958.1 - 1.3e-45 155.0 0.0 4.4e-45 153.3 0.0 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein Amino_oxidase PF01593.19 KZN91959.1 - 2.6e-67 227.8 0.0 2e-52 178.8 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN91959.1 - 4.3e-08 33.0 0.1 1.1e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN91959.1 - 2.1e-05 24.8 0.7 0.057 13.8 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN91959.1 - 2.5e-05 23.3 0.3 0.077 11.8 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN91959.1 - 0.00027 21.0 0.3 0.085 12.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN91959.1 - 0.001 18.8 0.2 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KZN91959.1 - 0.0044 16.1 0.4 0.037 13.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KZN91959.1 - 0.0077 15.3 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KZN91959.1 - 0.046 13.5 0.1 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KZN91959.1 - 0.061 12.8 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KZN91959.1 - 0.16 10.7 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KZN91959.1 - 0.19 10.1 0.3 2.1 6.7 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_43 PF04616.9 KZN91960.1 - 0.0041 16.2 7.3 0.0088 15.1 4.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Exo_endo_phos_2 PF14529.1 KZN91960.1 - 0.077 12.6 0.6 1 8.9 0.4 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase MFS_1 PF07690.11 KZN91961.1 - 1.5e-37 129.1 35.1 1.7e-37 128.9 24.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN91961.1 - 5.4e-12 45.0 13.4 5.4e-12 45.0 9.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2530 PF10745.4 KZN91961.1 - 0.54 10.2 0.0 0.54 10.2 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2530) CRPA PF05745.6 KZN91961.1 - 1.1 9.1 3.7 12 5.7 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Zn_clus PF00172.13 KZN91962.1 - 1.4e-10 40.9 10.6 2.2e-10 40.2 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMO PF03060.10 KZN91963.1 - 6.6e-29 101.0 2.2 1e-18 67.5 0.1 2.1 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KZN91963.1 - 1.3e-06 27.6 3.3 0.0032 16.4 1.6 2.1 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KZN91963.1 - 1.3e-05 24.2 3.0 1.5e-05 24.0 1.8 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KZN91963.1 - 0.0054 15.6 0.1 0.0093 14.9 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KZN91963.1 - 0.048 12.6 0.3 0.081 11.8 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase p450 PF00067.17 KZN91965.1 - 3.3e-69 233.6 0.0 4.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KZN91966.1 - 0.067 13.1 14.3 0.11 12.4 9.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L7Ae PF01248.21 KZN91967.1 - 2.3e-27 94.3 0.7 2.8e-27 94.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KZN91967.1 - 0.041 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 KZN91968.1 - 9.9e-26 89.9 0.2 5.1e-18 65.1 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN91968.1 - 1.3e-21 76.1 1.2 6.9e-09 35.6 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KZN91968.1 - 1.9e-20 71.5 1.7 7.5e-07 28.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KZN91968.1 - 9.3e-17 61.0 0.8 8.8e-07 29.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN91968.1 - 1.7e-12 46.2 0.1 0.001 19.0 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Steroid_dh PF02544.11 KZN91969.1 - 3.6e-12 46.2 0.6 3.6e-12 46.2 0.4 1.8 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3492 PF11997.3 KZN91969.1 - 0.092 12.2 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) BRI3BP PF14965.1 KZN91969.1 - 0.34 10.2 8.9 0.053 12.8 0.5 2.5 3 0 0 3 3 3 0 Negative regulator of p53/TP53 2OG-FeII_Oxy_2 PF13532.1 KZN91970.1 - 1.1e-11 44.9 0.0 5.7e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KZN91970.1 - 0.00036 20.7 0.0 0.0008 19.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.1 KZN91971.1 - 1.6e-18 67.0 0.8 3.2e-18 66.1 0.1 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 KZN91971.1 - 1.6e-16 60.8 0.1 1.6e-16 60.8 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KZN91971.1 - 8.9e-05 23.1 3.5 0.00011 22.8 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.6 KZN91972.1 - 3.3e-73 246.2 7.9 7.2e-73 245.1 5.5 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KZN91972.1 - 1.7e-06 28.0 27.3 0.00012 22.1 5.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KZN91972.1 - 2.4e-05 23.5 0.7 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 KZN91972.1 - 0.0018 17.9 17.8 0.0029 17.2 5.2 2.7 2 2 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KZN91972.1 - 0.008 16.3 16.9 0.015 15.4 1.5 3.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Sen15 PF09631.5 KZN91973.1 - 3e-13 49.8 0.0 4.7e-11 42.8 0.0 2.3 1 1 0 1 1 1 1 Sen15 protein tRNA_int_end_N2 PF12928.2 KZN91973.1 - 0.11 11.9 0.1 3.6 7.1 0.0 2.8 3 0 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term PH PF00169.24 KZN91974.1 - 4e-10 39.8 0.1 2e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 KZN91974.1 - 0.023 14.2 0.0 0.064 12.7 0.0 1.8 1 0 0 1 1 1 0 GRAM domain JmjN PF02375.12 KZN91974.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 jmjN domain bPH_3 PF14470.1 KZN91974.1 - 0.23 11.7 0.0 0.62 10.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain Kri1_C PF12936.2 KZN91975.1 - 7.1e-31 106.0 0.9 7.1e-31 106.0 0.7 3.5 2 2 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KZN91975.1 - 2e-28 98.5 17.2 2e-28 98.5 11.9 5.4 5 3 0 5 5 5 1 KRI1-like family LicD PF04991.8 KZN91975.1 - 4.7e-05 23.6 10.7 0.0001 22.5 1.4 2.4 2 0 0 2 2 2 2 LicD family AHS2 PF02626.10 KZN91975.1 - 0.12 11.6 1.0 0.23 10.7 0.7 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Mito_carr PF00153.22 KZN91976.1 - 3.1e-67 222.3 5.7 5.2e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1421 PF07223.6 KZN91977.1 - 2 8.1 45.2 2.5 7.7 31.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Stb3 PF10330.4 KZN91978.1 - 1.4e-39 133.6 0.0 2.3e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein COesterase PF00135.23 KZN91979.1 - 2.7e-88 296.9 0.0 4.7e-88 296.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN91979.1 - 1.2e-11 44.5 0.2 4.2e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN91979.1 - 9.5e-05 21.7 0.5 0.00019 20.7 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN91979.1 - 0.0014 18.3 0.2 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family TSP_C PF05735.7 KZN91979.1 - 0.036 13.6 0.3 0.062 12.8 0.2 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region Ribosomal_S19e PF01090.14 KZN91981.1 - 1.5e-56 189.7 0.1 1.7e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 KZN91982.1 - 1.9e-23 83.5 1.3 4.2e-23 82.4 0.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN91982.1 - 2.1e-14 53.5 0.0 6.8e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN91982.1 - 2.6e-10 40.2 0.0 9.4e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KZN91982.1 - 2.1e-09 37.0 0.0 8.2e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 KZN91982.1 - 5.7e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 KZN91982.1 - 0.00039 20.0 0.3 0.0037 16.8 0.1 2.4 2 1 0 2 2 2 1 Serine hydrolase DUF1749 PF08538.5 KZN91982.1 - 0.00046 19.1 0.0 0.08 11.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 KZN91982.1 - 0.00046 19.8 0.1 0.018 14.6 0.1 2.4 1 1 1 2 2 2 1 Lipase (class 3) PTPlike_phytase PF14566.1 KZN91982.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Hydrolase_4 PF12146.3 KZN91982.1 - 0.0018 18.1 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 KZN91982.1 - 0.0023 17.5 0.0 0.0081 15.7 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 KZN91982.1 - 0.0055 16.1 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 KZN91982.1 - 0.019 14.4 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LCAT PF02450.10 KZN91982.1 - 0.025 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_4 PF08386.5 KZN91982.1 - 0.042 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Y_phosphatase3 PF13350.1 KZN91982.1 - 0.1 12.8 0.2 0.47 10.6 0.1 2.0 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KZN91982.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF1057 PF06342.7 KZN91982.1 - 0.24 10.1 0.0 0.42 9.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) HTH_Tnp_Tc5 PF03221.11 KZN91983.1 - 3e-13 49.3 0.0 9.2e-13 47.8 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF755 PF05501.6 KZN91983.1 - 0.085 12.9 4.6 0.2 11.7 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TPR_MLP1_2 PF07926.7 KZN91983.1 - 0.28 10.9 8.1 0.21 11.3 2.1 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HTH_psq PF05225.11 KZN91983.1 - 0.43 10.1 0.0 0.43 10.1 0.0 3.0 4 0 0 4 4 4 0 helix-turn-helix, Psq domain ILVD_EDD PF00920.16 KZN91984.1 - 5.1e-203 675.2 0.9 5.8e-203 675.0 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.6 KZN91985.1 - 2e-19 69.7 0.2 2e-18 66.4 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Pex2_Pex12 PF04757.9 KZN91986.1 - 6.9e-40 136.8 0.1 6.9e-40 136.8 0.1 1.5 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 KZN91986.1 - 0.00074 19.3 5.5 0.0014 18.4 3.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN91986.1 - 0.97 9.2 3.4 0.35 10.6 0.2 1.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KZN91986.1 - 2.1 8.4 9.7 0.84 9.7 3.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HNH_2 PF13391.1 KZN91987.1 - 2.5e-14 52.8 0.0 6.1e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Phosphoesterase PF04185.9 KZN91988.1 - 3.7e-32 111.9 10.8 4.9e-32 111.5 4.9 2.3 2 1 0 2 2 2 1 Phosphoesterase family IBN_N PF03810.14 KZN91989.1 - 1.6e-15 56.7 0.0 1.7e-14 53.4 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KZN91989.1 - 1.2e-05 25.2 1.8 0.00035 20.5 0.0 3.1 2 1 0 2 2 2 1 Exportin 1-like protein Cellulase PF00150.13 KZN91990.1 - 2.1e-20 73.0 3.5 6.8e-20 71.4 2.5 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CN_hydrolase PF00795.17 KZN91991.1 - 1.1e-34 119.3 0.0 1.5e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FGase PF05013.7 KZN91991.1 - 0.062 13.1 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Glyco_hydro_2_N PF02837.13 KZN91992.1 - 3.5e-28 98.2 0.4 1.6e-27 96.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KZN91992.1 - 2.5e-15 56.1 0.2 2.1e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KZN91992.1 - 5.1e-12 46.2 0.1 1.4e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Protoglobin PF11563.3 KZN91993.1 - 1.4e-53 180.8 0.5 1.7e-53 180.4 0.3 1.1 1 0 0 1 1 1 1 Protoglobin DUF1153 PF06627.6 KZN91993.1 - 0.099 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) Aldedh PF00171.17 KZN91994.1 - 1.4e-136 455.4 0.5 1.7e-136 455.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN91994.1 - 8.2e-06 24.7 0.0 0.00013 20.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) GPI-anchored PF10342.4 KZN91995.1 - 4.5e-23 81.5 0.1 4.5e-23 81.5 0.1 2.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.13 KZN91996.1 - 4.1e-16 58.6 3.5 4.8e-16 58.4 0.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF16 PF01519.11 KZN91997.1 - 0.056 13.6 0.1 0.088 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_2 PF07716.10 KZN91997.1 - 0.069 12.9 12.1 0.11 12.2 8.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper COG2 PF06148.6 KZN91997.1 - 0.16 11.8 1.3 0.24 11.2 0.9 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Remorin_C PF03763.8 KZN91997.1 - 0.23 11.0 6.6 0.42 10.1 4.4 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region SGL PF08450.7 KZN91998.1 - 8.5e-75 251.2 0.0 1e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Aldedh PF00171.17 KZN91999.1 - 4.4e-185 615.4 0.1 5e-185 615.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KZN91999.1 - 0.00042 19.6 0.0 0.00075 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) IPI_T4 PF11634.3 KZN91999.1 - 0.059 13.2 0.0 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 EVE PF01878.13 KZN92000.1 - 1.7e-51 174.0 0.3 2.7e-51 173.3 0.2 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 KZN92000.1 - 7e-06 25.1 45.9 0.027 14.1 1.4 5.2 5 0 0 5 5 5 4 AT hook motif AhpC-TSA PF00578.16 KZN92001.1 - 9.6e-34 115.7 0.0 1.5e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KZN92001.1 - 7e-14 51.5 0.0 9.8e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KZN92001.1 - 6.8e-13 48.0 0.1 1.1e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.1 KZN92002.1 - 9.7e-21 73.2 0.1 2.3e-08 33.6 0.0 5.3 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KZN92002.1 - 7.2e-18 64.2 3.0 3.1e-10 39.9 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KZN92002.1 - 4.6e-11 42.4 6.0 0.00015 21.6 0.0 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KZN92002.1 - 5.1e-10 38.7 0.1 0.00084 19.0 0.0 4.4 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 KZN92002.1 - 3.9e-09 35.9 0.0 0.037 13.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KZN92002.1 - 1.7e-08 34.2 3.4 0.031 14.4 0.0 5.1 4 1 0 4 4 4 2 Kelch motif BTB PF00651.26 KZN92002.1 - 0.054 13.4 0.0 0.73 9.8 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Ribophorin_II PF05817.9 KZN92005.1 - 1.9e-22 79.2 0.0 2.3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II FMN_bind_2 PF04299.7 KZN92007.1 - 3.9e-54 182.6 0.0 4.7e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain LIP PF03583.9 KZN92007.1 - 0.029 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Sulfatase PF00884.18 KZN92008.1 - 1.7e-20 73.4 1.4 2.7e-20 72.7 1.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KZN92008.1 - 2.2e-07 30.5 0.1 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN92008.1 - 0.00025 19.5 0.0 0.00038 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 KZN92008.1 - 0.097 12.0 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Pkinase PF00069.20 KZN92009.1 - 5.5e-15 55.2 0.0 1.2e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92009.1 - 1.1e-13 50.8 0.0 4.6e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN92009.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN92009.1 - 0.013 14.8 0.1 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KZN92009.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 KZN92010.1 - 2.5e-29 102.3 1.8 3.3e-29 101.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN92010.1 - 2.1e-28 99.7 0.1 2.5e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN92010.1 - 2.1e-16 60.1 0.8 2.9e-16 59.6 0.6 1.1 1 0 0 1 1 1 1 KR domain PTR2 PF00854.16 KZN92011.1 - 5.9e-38 130.6 12.4 6.5e-37 127.1 8.6 2.2 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KZN92011.1 - 9.8e-09 34.3 21.8 2.3e-07 29.8 14.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 KZN92011.1 - 3.8 6.7 13.0 6.2 6.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF21 PLA2_B PF01735.13 KZN92012.1 - 1.6e-210 699.4 0.8 1.9e-210 699.2 0.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTCB-BRCT PF12738.2 KZN92013.1 - 0.17 11.8 0.1 0.68 9.8 0.1 2.0 1 1 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 KZN92013.1 - 0.22 11.7 0.0 0.51 10.5 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DAHP_synth_2 PF01474.11 KZN92014.1 - 2.8e-193 642.2 0.0 3.1e-193 642.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Tmemb_cc2 PF10267.4 KZN92015.1 - 0.32 9.5 11.8 0.41 9.1 8.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF822 PF05687.8 KZN92015.1 - 0.41 10.9 11.8 0.35 11.2 7.2 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) PAP1 PF08601.5 KZN92015.1 - 0.51 9.9 16.0 0.76 9.4 11.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 KZN92015.1 - 7.9 4.6 16.0 9.9 4.3 11.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 KZN92015.1 - 9.7 5.6 16.3 14 5.0 11.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3653 PF12375.3 KZN92017.1 - 0.067 13.4 0.2 0.19 11.9 0.0 1.7 1 1 1 2 2 2 0 Phage protein CRA_rpt PF07046.6 KZN92017.1 - 0.43 10.6 3.5 2 8.4 0.5 2.3 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat MFS_1 PF07690.11 KZN92018.1 - 1.1e-28 100.0 24.2 1.8e-28 99.2 16.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG11 PF10377.4 KZN92019.1 - 0.012 15.5 0.1 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 11 MA-Mit PF09245.5 KZN92019.1 - 0.13 11.4 0.3 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Aldose_epim PF01263.15 KZN92020.1 - 2.8e-38 131.7 0.1 3.6e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AA_permease_2 PF13520.1 KZN92021.1 - 6.8e-45 153.3 48.4 8.3e-45 153.0 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN92021.1 - 4.3e-19 68.2 41.3 6.1e-19 67.7 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4381 PF14316.1 KZN92021.1 - 0.1 12.6 0.3 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Bac_thur_toxin PF01338.13 KZN92022.1 - 0.052 12.7 0.2 0.079 12.1 0.2 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin PsbN PF02468.10 KZN92022.1 - 0.7 9.5 3.6 2.7 7.6 2.5 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) SNF PF00209.13 KZN92023.1 - 1.2e-70 238.5 37.5 7e-45 153.4 11.5 2.8 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family DUF3810 PF12725.2 KZN92023.1 - 0.27 10.1 0.8 0.44 9.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Aldo_ket_red PF00248.16 KZN92024.1 - 2.3e-49 167.7 0.0 2.9e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Seadorna_Vp10 PF07322.6 KZN92024.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 PUA PF01472.15 KZN92024.1 - 0.14 11.8 0.1 0.39 10.4 0.1 1.7 1 0 0 1 1 1 0 PUA domain Rif1_N PF12231.3 KZN92025.1 - 7.5e-145 482.5 0.1 1.2e-144 481.8 0.1 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 KZN92026.1 - 2.3e-127 425.4 0.0 2.8e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Cnd3 PF12719.2 KZN92026.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Polysacc_synt_4 PF04669.8 KZN92027.1 - 6.6e-20 71.2 2.2 4.9e-19 68.4 1.5 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.18 KZN92028.1 - 4.6e-72 242.7 26.7 4.8e-36 124.6 4.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN92028.1 - 4.3e-61 205.1 0.0 5e-29 101.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KZN92028.1 - 3.3e-19 68.9 0.5 1.4e-08 34.2 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN92028.1 - 2.4e-12 47.4 0.0 0.18 11.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KZN92028.1 - 4.2e-09 35.7 0.6 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KZN92028.1 - 4.3e-08 34.0 0.0 0.0096 16.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KZN92028.1 - 7.1e-08 32.6 1.3 0.0057 16.7 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KZN92028.1 - 4.7e-07 29.4 0.1 0.1 11.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KZN92028.1 - 1e-06 28.9 1.9 0.03 14.3 0.4 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_10 PF12846.2 KZN92028.1 - 7.5e-06 25.5 2.7 0.0074 15.7 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 KZN92028.1 - 1.3e-05 25.5 0.1 0.11 12.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN92028.1 - 1.9e-05 23.9 0.5 0.23 10.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_13 PF13166.1 KZN92028.1 - 0.00011 20.9 0.2 0.87 7.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KZN92028.1 - 0.00014 21.7 0.1 0.48 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KZN92028.1 - 0.00029 20.6 0.0 1.4 8.8 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KZN92028.1 - 0.00039 20.1 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KZN92028.1 - 0.00065 19.5 0.9 0.81 9.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 KZN92028.1 - 0.00075 19.2 0.1 1.4 8.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KZN92028.1 - 0.00099 18.6 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family ABC_ATPase PF09818.4 KZN92028.1 - 0.001 17.7 1.5 0.051 12.1 0.1 3.2 4 1 0 4 4 4 1 Predicted ATPase of the ABC class DUF3987 PF13148.1 KZN92028.1 - 0.0021 16.7 0.1 1.2 7.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 KZN92028.1 - 0.0063 16.6 0.0 3.6 7.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_15 PF13175.1 KZN92028.1 - 0.0082 15.2 0.8 3.2 6.6 0.0 3.6 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 KZN92028.1 - 0.012 15.5 1.4 2.8 7.9 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 KZN92028.1 - 0.014 15.0 0.2 2 8.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KZN92028.1 - 0.017 15.4 0.4 2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KZN92028.1 - 0.024 14.3 0.1 0.89 9.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain APS_kinase PF01583.15 KZN92028.1 - 0.027 14.1 0.1 9.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase KaiC PF06745.8 KZN92028.1 - 0.041 13.0 4.7 4 6.5 0.0 3.8 4 0 0 4 4 4 0 KaiC Sigma54_activat PF00158.21 KZN92028.1 - 0.068 12.6 0.0 9.3 5.6 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain CbiA PF01656.18 KZN92028.1 - 0.068 12.5 0.7 2 7.7 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Gtr1_RagA PF04670.7 KZN92028.1 - 0.11 11.5 0.4 12 4.9 0.0 2.9 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region Abhydrolase_6 PF12697.2 KZN92029.1 - 4.6e-16 59.3 1.1 5.4e-16 59.1 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN92029.1 - 0.002 17.8 0.1 0.0033 17.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_kinase PF00696.23 KZN92030.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family RSN1_TM PF13967.1 KZN92031.1 - 0.05 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Epiglycanin_C PF14654.1 KZN92031.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Methyltransf_2 PF00891.13 KZN92032.1 - 3.4e-28 98.4 0.4 1.6e-27 96.2 0.3 2.0 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KZN92032.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 KZN92033.1 - 4.8e-10 39.1 7.4 8.1e-10 38.4 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92033.1 - 1e-05 24.5 0.1 1.6e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain But2 PF09792.4 KZN92035.1 - 9e-56 187.6 1.5 1.5e-55 186.8 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain UNC-50 PF05216.8 KZN92036.1 - 0.0079 15.4 2.5 0.017 14.3 1.8 1.5 1 0 0 1 1 1 1 UNC-50 family MARVEL PF01284.18 KZN92036.1 - 0.083 12.7 15.7 0.12 12.2 10.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain Polysacc_synt_3 PF13440.1 KZN92036.1 - 0.17 11.3 13.0 0.085 12.3 6.5 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PLDc_N PF13396.1 KZN92036.1 - 2 8.1 11.4 0.072 12.7 1.4 2.9 2 1 0 2 2 2 0 Phospholipase_D-nuclease N-terminal 7TMR-DISM_7TM PF07695.6 KZN92036.1 - 3.6 7.2 18.8 0.23 11.1 8.3 1.9 1 1 0 2 2 2 0 7TM diverse intracellular signalling Cation_ATPase_C PF00689.16 KZN92036.1 - 8 5.9 11.4 33 3.9 5.3 2.5 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Acetyltransf_3 PF13302.1 KZN92037.1 - 7e-38 129.9 0.0 8.4e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN92037.1 - 0.00037 20.4 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN92037.1 - 0.00038 20.4 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN92037.1 - 0.00085 19.3 0.1 0.0057 16.6 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3515 PF12028.3 KZN92037.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) DAO PF01266.19 KZN92038.1 - 4.3e-57 193.6 0.0 4.9e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN92038.1 - 0.0035 16.2 5.4 0.028 13.2 3.8 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KZN92038.1 - 0.0038 16.3 1.1 0.0072 15.4 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN92038.1 - 0.0067 16.0 0.1 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KZN92038.1 - 0.019 14.8 1.4 0.31 10.9 1.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN92038.1 - 0.022 14.5 0.0 5.3 6.8 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KZN92038.1 - 0.034 14.1 0.2 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KZN92038.1 - 0.04 12.7 2.5 0.13 11.0 0.4 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KZN92038.1 - 0.1 11.0 1.7 5.2 5.4 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Ribosomal_S2 PF00318.15 KZN92039.1 - 1.6e-49 168.0 0.0 2.4e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S2 BBE PF08031.7 KZN92039.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Rick_17kDa_Anti PF05433.10 KZN92040.1 - 9.6e-05 21.9 14.4 0.00018 21.0 10.0 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF533 PF04391.7 KZN92040.1 - 0.014 14.7 2.2 0.014 14.7 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF533) TraT PF05818.7 KZN92040.1 - 0.1 11.9 1.4 0.17 11.2 0.9 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 KZN92040.1 - 0.16 11.6 14.9 0.64 9.6 10.2 2.1 1 1 0 1 1 1 0 Glycine zipper Transgly_assoc PF04226.8 KZN92040.1 - 0.24 11.4 11.9 0.4 10.7 8.2 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein TatD_DNase PF01026.16 KZN92041.1 - 0.031 13.4 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase SURF6 PF04935.7 KZN92042.1 - 5e-49 166.4 36.5 5e-49 166.4 25.3 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KZN92042.1 - 4.8e-23 81.0 2.0 4.8e-23 81.0 1.4 9.0 7 2 0 7 7 7 2 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.22 KZN92043.1 - 5.3e-14 51.1 16.4 3.1e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KZN92043.1 - 2.7e-12 46.8 10.8 4.3e-12 46.2 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KZN92043.1 - 1.8e-10 40.4 23.7 2.4e-08 33.6 9.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KZN92043.1 - 2.9e-10 40.2 9.4 5.4e-10 39.3 6.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KZN92043.1 - 9.7e-10 38.1 5.2 5.7e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KZN92043.1 - 1e-09 38.9 8.3 6.1e-05 23.6 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 KZN92043.1 - 6e-09 36.1 2.3 0.00067 19.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 KZN92043.1 - 9e-09 35.2 20.1 1.6e-05 24.8 8.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KZN92043.1 - 1.1e-07 31.3 14.3 0.00057 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KZN92043.1 - 4.1e-07 29.8 12.5 0.00056 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KZN92043.1 - 5.8e-07 29.0 17.4 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KZN92043.1 - 4.2e-05 23.8 9.9 0.014 15.8 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 KZN92043.1 - 0.003 18.0 12.7 0.32 11.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 KZN92043.1 - 0.0083 16.4 15.7 0.29 11.5 3.2 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 KZN92043.1 - 0.016 15.3 4.3 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 KZN92043.1 - 0.018 15.5 17.5 0.039 14.5 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 KZN92043.1 - 0.11 12.4 4.4 0.18 11.6 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain PP-binding PF00550.20 KZN92044.1 - 6.8e-11 42.2 0.2 9.4e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KZN92044.1 - 1.7e-06 27.9 0.1 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 KZN92044.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal subunit 39S GPP34 PF05719.6 KZN92045.1 - 4.6e-64 216.2 0.1 6.1e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 KZN92046.1 - 0.0079 17.0 0.1 0.016 16.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN92046.1 - 0.053 13.2 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2183 PF09949.4 KZN92047.1 - 1.8e-31 107.9 0.0 3.7e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) ApoA-II PF04711.8 KZN92047.1 - 0.099 12.5 0.3 0.49 10.3 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) His_Phos_1 PF00300.17 KZN92048.1 - 3.2e-29 102.0 0.1 3.8e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF367 PF04034.8 KZN92049.1 - 3.5e-49 165.6 0.0 5.4e-49 165.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KZN92049.1 - 3.9e-11 42.3 1.0 8.5e-11 41.2 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Nop14 PF04147.7 KZN92049.1 - 1.5 6.6 23.5 1.8 6.3 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KZN92049.1 - 1.8 7.7 21.9 2.6 7.2 15.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KZN92049.1 - 3.5 5.5 14.1 4.3 5.2 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 KZN92049.1 - 3.8 7.1 18.5 6.4 6.4 12.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 KZN92049.1 - 8.5 4.7 20.4 11 4.3 14.1 1.1 1 0 0 1 1 1 0 Daxx Family VHS PF00790.14 KZN92050.1 - 3.2e-43 146.7 0.0 1.2e-42 144.8 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KZN92050.1 - 6.9e-25 86.9 1.2 1.9e-24 85.5 0.8 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KZN92050.1 - 3.3e-21 75.7 0.5 7.3e-21 74.6 0.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Mei5 PF10376.4 KZN92050.1 - 0.067 12.7 2.5 0.067 12.7 0.6 1.8 1 1 0 1 1 1 0 Double-strand recombination repair protein DUF605 PF04652.11 KZN92050.1 - 3.1 7.1 20.5 4.7 6.4 14.2 1.3 1 0 0 1 1 1 0 Vta1 like CBS PF00571.23 KZN92052.1 - 2.5e-21 75.1 3.2 1.7e-05 24.4 0.0 5.5 4 1 2 6 6 6 5 CBS domain Sugar_tr PF00083.19 KZN92053.1 - 0.00038 19.1 1.2 0.0004 19.0 0.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92053.1 - 0.061 12.0 4.0 0.16 10.6 2.8 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2955 PF11168.3 KZN92053.1 - 0.27 10.8 5.0 2.5 7.7 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) Zn_clus PF00172.13 KZN92054.1 - 1.7e-09 37.4 9.4 2.8e-09 36.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92054.1 - 0.0063 15.4 0.1 0.024 13.5 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Vezatin PF12632.2 KZN92054.1 - 0.071 12.1 0.5 0.14 11.1 0.3 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes YvfG PF09628.5 KZN92054.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 YvfG protein PhyH PF05721.8 KZN92055.1 - 5.6e-29 101.6 0.1 7.4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KZN92055.1 - 3.3e-06 27.3 0.0 7.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Aminotran_5 PF00266.14 KZN92056.1 - 1.9e-27 96.0 0.0 2.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 KZN92056.1 - 1.5e-25 89.1 0.0 2.7e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KZN92056.1 - 9.8e-21 73.6 0.0 1.8e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Suf PF05843.9 KZN92058.1 - 9.5e-05 22.2 4.1 0.012 15.4 0.1 3.1 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KZN92058.1 - 0.001 19.6 6.1 2.2 9.0 0.1 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92058.1 - 0.0035 17.8 4.2 79 4.3 0.0 6.7 5 2 1 7 7 7 0 Tetratricopeptide repeat FAT PF02259.18 KZN92058.1 - 0.0072 15.3 0.1 0.039 12.9 0.0 2.3 3 0 0 3 3 3 1 FAT domain DEAD PF00270.24 KZN92059.1 - 2e-41 141.2 0.0 1.6e-40 138.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN92059.1 - 2.8e-26 91.1 0.2 5.6e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 KZN92059.1 - 0.0064 16.7 3.7 0.029 14.6 2.6 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 KZN92059.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) ResIII PF04851.10 KZN92059.1 - 0.067 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M1 PF01433.15 KZN92060.1 - 2.7e-144 481.0 0.5 3.4e-144 480.7 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KZN92060.1 - 2.2e-96 322.9 0.0 2.8e-95 319.2 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KZN92060.1 - 2.4e-19 69.6 0.1 5.6e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 KZN92060.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) AA_permease_2 PF13520.1 KZN92061.1 - 8.3e-97 324.4 39.3 1e-96 324.0 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN92061.1 - 1.9e-22 79.3 33.7 2.7e-22 78.7 23.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3543 PF12063.3 KZN92062.1 - 4.3e-97 324.0 0.0 6.1e-97 323.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KZN92062.1 - 3.3e-62 209.9 0.0 5.6e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92062.1 - 1.5e-42 145.4 0.0 2.6e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92062.1 - 0.049 12.5 0.0 0.59 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like CTP_transf_1 PF01148.15 KZN92063.1 - 3.4e-05 23.6 8.8 0.001 18.8 0.3 3.7 4 0 0 4 4 4 2 Cytidylyltransferase family zf-C2H2 PF00096.21 KZN92064.1 - 4e-12 45.7 12.1 2.3e-06 27.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN92064.1 - 4.6e-10 39.0 10.7 0.00026 21.1 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN92064.1 - 1.7e-07 31.1 11.1 2.8e-06 27.3 3.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KZN92064.1 - 1e-05 25.4 5.5 0.0023 18.0 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN92064.1 - 0.00064 19.8 8.8 0.0032 17.6 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KZN92064.1 - 0.018 14.9 9.4 0.021 14.7 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KZN92064.1 - 0.46 10.6 3.8 5.8 7.0 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KZN92064.1 - 3.5 7.4 7.2 1.4 8.7 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger PITH PF06201.8 KZN92065.1 - 2.7e-38 131.1 0.0 4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KZN92065.1 - 2.2e-27 94.7 0.0 3.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KZN92065.1 - 2.4e-07 30.9 0.2 1.1e-06 28.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KZN92065.1 - 2.6e-07 30.6 0.0 0.00063 19.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KZN92065.1 - 0.00068 19.3 0.0 0.34 10.5 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KZN92065.1 - 0.00071 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KZN92065.1 - 0.0056 16.6 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KZN92065.1 - 0.0078 15.7 0.2 0.39 10.2 0.0 2.2 1 1 1 2 2 2 1 Redoxin HyaE PF07449.6 KZN92065.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DASH_Spc34 PF08657.5 KZN92065.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 zf-CSL PF05207.8 KZN92066.1 - 1.1e-16 60.0 2.1 1.6e-16 59.5 1.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KZN92066.1 - 7.4e-14 51.2 0.1 1.9e-13 49.9 0.1 1.7 1 1 0 1 1 1 1 DnaJ domain peroxidase PF00141.18 KZN92067.1 - 5.2e-51 173.3 0.0 8e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.13 KZN92068.1 - 2.4e-35 120.8 0.1 6.6e-35 119.4 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.12 KZN92069.1 - 1.5e-81 274.5 15.8 1.8e-81 274.2 10.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HrpB1_HrpK PF09613.5 KZN92069.1 - 0.05 13.1 0.2 0.094 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Aminotran_3 PF00202.16 KZN92070.1 - 2.6e-104 348.7 0.0 3.3e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KZN92070.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_membrane PF00664.18 KZN92071.1 - 7e-48 163.4 38.0 4.9e-27 95.0 14.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KZN92071.1 - 8.4e-46 155.6 0.1 5.1e-25 88.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KZN92071.1 - 3.1e-07 30.6 0.4 0.088 12.7 0.1 4.2 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KZN92071.1 - 6.8e-07 29.2 0.1 0.039 13.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.14 KZN92071.1 - 2.6e-06 26.8 2.2 0.38 9.9 0.1 3.6 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KZN92071.1 - 4.5e-06 27.1 0.2 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 KZN92071.1 - 3e-05 23.2 0.0 0.019 14.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KZN92071.1 - 4.8e-05 23.4 1.9 0.18 11.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 KZN92071.1 - 7.1e-05 23.6 0.7 0.32 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN92071.1 - 0.00018 20.7 0.1 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KZN92071.1 - 0.00037 19.9 4.9 0.079 12.4 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain ArgK PF03308.11 KZN92071.1 - 0.0024 16.6 0.5 0.97 8.1 0.1 2.3 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 KZN92071.1 - 0.0032 16.8 0.0 0.66 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KZN92071.1 - 0.0042 16.5 1.1 2.4 7.5 0.0 3.2 2 1 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KZN92071.1 - 0.013 15.6 1.2 8.4 6.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 KZN92071.1 - 0.031 13.7 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 KZN92071.1 - 0.038 13.7 6.2 0.19 11.5 0.0 2.9 3 0 0 3 3 2 0 Dynamin family ATP-synt_ab PF00006.20 KZN92071.1 - 0.059 12.8 0.1 7.6 5.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 KZN92071.1 - 0.063 13.0 6.5 0.2 11.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF815 PF05673.8 KZN92071.1 - 0.094 11.6 0.2 8.1 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 KZN92071.1 - 0.12 11.3 0.6 10 5.0 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 KZN92071.1 - 0.21 11.8 9.0 0.34 11.1 0.1 3.4 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.1 KZN92071.1 - 1.2 8.7 4.9 3.6 7.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KZN92071.1 - 2.2 8.1 5.5 1.1 9.2 0.1 2.9 3 0 0 3 3 3 0 AAA domain DUF788 PF05620.6 KZN92071.1 - 2.7 7.8 8.1 0.3 10.9 0.7 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF788) AAA_18 PF13238.1 KZN92071.1 - 3.8 7.8 7.1 11 6.3 0.0 3.0 4 0 0 4 4 2 0 AAA domain FMN_red PF03358.10 KZN92072.1 - 6e-30 103.7 0.0 8.1e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KZN92072.1 - 2.7e-08 33.5 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3328 PF11807.3 KZN92073.1 - 0.00071 19.3 1.7 0.0078 15.9 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Virul_fac_BrkB PF03631.10 KZN92073.1 - 0.065 12.5 0.3 0.089 12.1 0.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB ORC4_C PF14629.1 KZN92076.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF3666 PF12408.3 KZN92077.1 - 0.12 11.4 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Sugar_tr PF00083.19 KZN92078.1 - 5.2e-30 104.4 29.4 2e-23 82.7 5.6 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 KZN92078.1 - 6.2e-26 90.9 27.0 6.2e-26 90.9 18.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KZN92078.1 - 0.0008 18.0 22.4 0.0018 16.8 4.2 3.1 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like Transferase PF02458.10 KZN92079.1 - 1.6e-42 145.4 0.0 2.5e-20 72.3 0.0 3.0 3 0 0 3 3 3 3 Transferase family Glyco_hydro_47 PF01532.15 KZN92080.1 - 7.1e-25 87.5 0.0 1.5e-16 60.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Pyr_redox_3 PF13738.1 KZN92081.1 - 2.1e-23 83.4 0.0 3e-22 79.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN92081.1 - 1.4e-15 56.4 0.1 5.6e-13 47.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KZN92081.1 - 1.5e-12 47.7 0.0 1.4e-10 41.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN92081.1 - 9.7e-11 41.1 0.1 3.4e-08 32.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KZN92081.1 - 2e-06 28.1 0.2 0.17 12.3 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN92081.1 - 3.5e-06 26.9 0.0 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KZN92081.1 - 2.2e-05 23.6 0.0 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KZN92081.1 - 0.00075 18.4 0.0 0.0038 16.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KZN92081.1 - 0.00093 19.0 0.7 1.4 8.6 0.0 3.2 2 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KZN92081.1 - 0.0032 16.5 0.0 0.045 12.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 KZN92081.1 - 0.0038 16.3 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KZN92081.1 - 0.0043 15.5 0.5 0.019 13.4 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 KZN92081.1 - 0.0058 15.5 0.0 0.3 9.9 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KZN92081.1 - 0.02 14.5 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KZN92081.1 - 0.038 14.0 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.2 KZN92081.1 - 0.052 13.9 0.4 0.86 10.0 0.0 2.8 3 0 0 3 3 3 0 SnoaL-like domain NAD_binding_7 PF13241.1 KZN92081.1 - 0.063 13.5 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 KZN92081.1 - 0.07 12.1 0.2 1.1 8.2 0.0 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KZN92081.1 - 0.098 11.5 0.1 0.95 8.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A SLAC1 PF03595.12 KZN92083.1 - 1.4e-55 188.2 37.0 1.6e-55 188.0 25.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HemY_N PF07219.8 KZN92083.1 - 3.1 7.3 6.3 7.4 6.1 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus CDC45 PF02724.9 KZN92085.1 - 0.14 10.1 0.8 0.19 9.6 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIIC_delta PF12657.2 KZN92086.1 - 0.0031 17.2 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term F-box PF00646.28 KZN92086.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KZN92086.1 - 0.0079 15.8 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KZN92087.1 - 1.2e-18 66.9 0.1 4.3e-18 65.1 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92087.1 - 1.2e-06 28.3 7.0 2.8e-06 27.1 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIF PF03031.13 KZN92088.1 - 4.2e-40 137.0 0.1 5.9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KZN92088.1 - 0.075 13.2 0.2 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2893 PF11459.3 KZN92089.1 - 0.072 12.8 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) JAB PF01398.16 KZN92090.1 - 1.9e-35 121.0 0.0 4.6e-35 119.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KZN92090.1 - 8.2e-26 90.3 2.5 1.4e-25 89.5 1.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KZN92090.1 - 4.7e-09 35.7 0.0 9.9e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 KZN92090.1 - 0.061 13.0 0.2 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF771 PF05595.6 KZN92090.1 - 0.24 11.3 1.6 5.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF771) Hist_deacetyl PF00850.14 KZN92091.1 - 4.4e-80 269.2 0.0 8.8e-80 268.2 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L14 PF00238.14 KZN92092.1 - 3.7e-33 113.8 0.0 4.2e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Metallophos PF00149.23 KZN92093.1 - 2e-10 40.3 1.6 6.3e-10 38.7 1.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Vps8 PF12816.2 KZN92093.1 - 0.091 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 PH PF00169.24 KZN92094.1 - 1.6e-11 44.2 0.0 5.6e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 KZN92094.1 - 2.9e-09 36.6 0.1 5.1e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KZN92094.1 - 3.5e-08 32.8 0.0 7.3e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KZN92094.1 - 8.9e-07 28.2 0.0 1.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 KZN92094.1 - 4.4e-06 26.9 0.1 1.2e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 KZN92094.1 - 0.0055 16.8 0.1 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-MIZ PF02891.15 KZN92095.1 - 3.9e-10 39.0 0.4 8.3e-10 38.0 0.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KZN92095.1 - 0.00031 20.2 0.3 0.00075 18.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rubredoxin PF00301.15 KZN92095.1 - 0.59 10.0 2.4 0.72 9.7 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin Nsp1_C PF05064.8 KZN92097.1 - 1e-40 138.0 0.5 1e-40 138.0 0.4 1.9 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KZN92097.1 - 2.1e-08 34.3 141.1 8e-05 22.8 24.6 5.2 1 1 2 3 3 3 2 Nucleoporin FG repeat region Laminin_II PF06009.7 KZN92097.1 - 0.025 14.3 8.0 7.6 6.2 1.5 3.1 1 1 2 3 3 3 0 Laminin Domain II ParB PF08775.5 KZN92097.1 - 0.045 14.0 1.1 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 ParB family MscS_porin PF12795.2 KZN92097.1 - 0.28 10.4 7.7 2 7.6 1.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 KZN92097.1 - 0.5 8.7 4.2 0.32 9.4 0.8 1.7 1 1 1 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 KZN92097.1 - 0.53 10.1 6.0 0.37 10.6 3.0 1.5 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 KZN92097.1 - 0.93 9.2 2.9 1 9.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 KZN92097.1 - 0.95 8.4 5.4 1.4 7.8 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 KZN92097.1 - 2.7 6.5 7.6 0.66 8.5 0.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KZN92097.1 - 2.8 7.4 6.6 8.5 5.9 4.6 1.7 1 1 0 1 1 1 0 IncA protein IATP PF04568.7 KZN92098.1 - 1.9e-25 88.7 0.2 2.1e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 KZN92098.1 - 0.021 13.7 0.0 0.021 13.7 0.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vac_Fusion PF02346.11 KZN92098.1 - 0.068 12.6 1.1 0.092 12.1 0.7 1.2 1 0 0 1 1 1 0 Chordopoxvirus fusion protein BLOC1_2 PF10046.4 KZN92098.1 - 0.076 13.1 0.8 0.092 12.8 0.5 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LEA_6 PF10714.4 KZN92098.1 - 0.16 11.7 3.7 0.24 11.2 2.1 1.7 1 1 1 2 2 2 0 Late embryogenesis abundant protein 18 Sds3 PF08598.6 KZN92098.1 - 0.19 11.2 3.4 0.25 10.8 2.4 1.1 1 0 0 1 1 1 0 Sds3-like DASH_Dad2 PF08654.5 KZN92098.1 - 0.22 11.5 1.8 0.28 11.1 1.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 RBD-FIP PF09457.5 KZN92098.1 - 0.33 10.8 3.8 0.52 10.1 2.6 1.3 1 0 0 1 1 1 0 FIP domain bZIP_2 PF07716.10 KZN92098.1 - 0.45 10.3 6.3 0.62 9.9 4.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper 14-3-3 PF00244.15 KZN92099.1 - 9.8e-115 381.5 5.5 1.1e-114 381.3 3.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3456 PF11938.3 KZN92099.1 - 0.056 13.4 0.3 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DUF2205 PF10224.4 KZN92100.1 - 1.2e-30 104.8 2.9 1.2e-30 104.8 2.0 1.7 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 KZN92100.1 - 0.0022 16.3 4.2 0.0025 16.2 2.9 1.0 1 0 0 1 1 1 1 Transmembrane protein Dynamitin PF04912.9 KZN92100.1 - 0.012 14.4 0.7 0.017 13.9 0.5 1.1 1 0 0 1 1 1 0 Dynamitin DUF4140 PF13600.1 KZN92100.1 - 0.015 15.7 1.2 0.031 14.7 0.8 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 KZN92100.1 - 0.019 15.2 2.5 0.033 14.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spectrin PF00435.16 KZN92100.1 - 0.028 14.7 1.0 0.043 14.1 0.7 1.3 1 0 0 1 1 1 0 Spectrin repeat IncA PF04156.9 KZN92100.1 - 0.037 13.6 0.7 0.038 13.6 0.5 1.2 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 KZN92100.1 - 0.041 13.7 3.2 0.046 13.5 1.4 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 KZN92100.1 - 0.048 13.3 4.4 0.3 10.8 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.5 KZN92100.1 - 0.052 13.3 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DivIC PF04977.10 KZN92100.1 - 0.061 12.8 2.1 0.1 12.1 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 KZN92100.1 - 0.087 12.7 4.9 0.12 12.2 3.4 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KZN92100.1 - 0.091 12.5 0.5 0.12 12.1 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glutaredoxin2_C PF04399.8 KZN92100.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain OmpH PF03938.9 KZN92100.1 - 0.27 11.1 4.9 0.36 10.7 3.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 KZN92100.1 - 0.5 10.6 3.7 1.8 8.9 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Glyco_hydro_76 PF03663.9 KZN92101.1 - 3.6e-20 72.6 1.1 1.3e-12 47.7 0.0 3.7 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 RRM_1 PF00076.17 KZN92102.1 - 8.9e-12 44.4 0.0 4.8e-05 22.9 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN92102.1 - 3.4e-10 39.7 0.0 9.5e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN92102.1 - 5.3e-10 38.9 0.0 6.7e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bax1-I PF01027.15 KZN92103.1 - 9.6e-31 106.9 11.2 1.5e-30 106.3 7.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 KZN92103.1 - 0.59 10.2 5.7 6.2 6.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) DUF4282 PF14110.1 KZN92103.1 - 1.9 8.7 6.7 4.8 7.4 0.2 3.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4282) CGI-121 PF08617.5 KZN92104.1 - 1.3e-52 177.7 0.4 1.4e-52 177.5 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 VAR1 PF05316.7 KZN92104.1 - 0.058 11.9 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Slx4 PF09494.5 KZN92105.1 - 2.2e-29 100.9 0.0 3.9e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.13 KZN92106.1 - 0.00012 21.9 8.9 0.0002 21.2 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AKNA PF12443.3 KZN92106.1 - 0.0035 17.3 1.4 0.0036 17.2 0.1 1.7 2 0 0 2 2 2 1 AT-hook-containing transcription factor ADIP PF11559.3 KZN92106.1 - 0.0068 16.3 0.6 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KZN92106.1 - 0.012 15.8 1.0 0.023 14.9 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) WXG100 PF06013.7 KZN92106.1 - 0.015 15.3 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG bZIP_2 PF07716.10 KZN92106.1 - 0.015 15.1 2.8 0.039 13.7 2.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 KZN92106.1 - 0.017 14.9 0.8 0.03 14.1 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 KZN92106.1 - 0.039 13.9 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Prefoldin PF02996.12 KZN92106.1 - 0.042 13.4 0.9 0.072 12.7 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit DivIC PF04977.10 KZN92106.1 - 0.05 13.0 1.2 0.082 12.4 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.6 KZN92106.1 - 0.051 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Ded_cyto PF06920.8 KZN92106.1 - 0.055 12.7 0.6 0.082 12.2 0.4 1.2 1 0 0 1 1 1 0 Dedicator of cytokinesis FliD_C PF07195.7 KZN92106.1 - 0.056 12.7 0.3 0.072 12.3 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sec3_C_2 PF15278.1 KZN92106.1 - 0.07 13.2 0.1 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit IncA PF04156.9 KZN92106.1 - 0.082 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 KZN92106.1 - 0.096 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HIPIP PF01355.12 KZN92106.1 - 0.5 10.5 3.5 1 9.5 2.4 1.5 1 0 0 1 1 1 0 High potential iron-sulfur protein ER_lumen_recept PF00810.13 KZN92108.1 - 9.4e-38 129.9 7.7 1.5e-37 129.3 5.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KZN92108.1 - 0.059 12.9 0.1 0.059 12.9 0.0 3.8 4 1 0 4 4 4 0 PQ loop repeat Myb_DNA-binding PF00249.26 KZN92109.1 - 1.8e-12 47.0 6.1 5.5e-07 29.5 2.0 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KZN92109.1 - 2.6e-11 43.4 3.3 2.3e-06 27.6 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Transp_cyt_pur PF02133.10 KZN92110.1 - 8.3e-18 64.1 36.6 1.2e-17 63.6 25.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 KZN92111.1 - 1.8e-37 128.0 0.0 1.3e-36 125.2 0.0 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase subunit Vb zf-UBP PF02148.14 KZN92111.1 - 0.089 12.9 0.4 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-bind_6 PF13921.1 KZN92112.1 - 4.3e-07 29.9 0.5 0.0092 16.0 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN92112.1 - 0.0001 22.2 0.9 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain PROCN PF08083.6 KZN92113.1 - 1.2e-222 738.6 6.6 2.1e-222 737.9 4.5 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KZN92113.1 - 1.7e-125 416.9 1.6 3.1e-125 416.0 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KZN92113.1 - 2e-99 329.5 0.2 9.3e-61 203.8 0.3 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KZN92113.1 - 3.6e-78 260.4 2.1 1.1e-77 258.8 1.4 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KZN92113.1 - 8e-67 223.0 0.2 1.8e-66 221.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 KZN92113.1 - 4.7e-49 167.0 9.6 3.1e-30 105.5 0.0 3.4 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 KZN92113.1 - 6e-46 155.2 0.0 1.5e-45 153.9 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KZN92113.1 - 6.5e-44 147.7 0.1 1.9e-43 146.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hint_2 PF13403.1 KZN92113.1 - 0.0017 18.3 0.1 0.027 14.4 0.1 2.4 1 1 0 1 1 1 1 Hint domain DUF3753 PF12575.3 KZN92113.1 - 0.1 12.4 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 KZN92113.1 - 0.29 9.8 1.5 0.96 8.1 0.7 1.9 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 KZN92114.1 - 1.5e-34 118.0 0.5 2.1e-34 117.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Fork_head PF00250.13 KZN92115.1 - 2.6e-15 56.2 0.1 5.2e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 KZN92116.1 - 1.3e-63 213.7 5.3 2.2e-63 213.0 3.7 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KZN92116.1 - 1.7e-55 185.9 3.5 2.9e-55 185.1 2.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein CENP-Q PF13094.1 KZN92116.1 - 0.04 13.9 2.4 0.27 11.2 1.7 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit XLF PF09302.6 KZN92117.1 - 9.3e-32 110.1 1.5 1.4e-31 109.5 1.1 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 KZN92118.1 - 2.2e-29 100.2 14.9 4.2e-09 35.9 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KZN92118.1 - 5.2e-06 26.2 0.1 0.13 11.9 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A zf-rbx1 PF12678.2 KZN92118.1 - 3.2 7.9 6.8 0.96 9.6 0.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger ABC_tran PF00005.22 KZN92119.1 - 3.1e-33 114.9 0.0 1.5e-32 112.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KZN92119.1 - 1.6e-25 90.1 8.5 1.6e-25 90.1 5.9 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 KZN92119.1 - 4.3e-08 32.6 0.2 2.2e-06 27.0 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KZN92119.1 - 0.00021 21.3 0.0 0.16 11.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN92119.1 - 0.0015 18.5 0.1 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KZN92119.1 - 0.0052 16.6 0.3 0.059 13.2 0.2 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KZN92119.1 - 0.0082 15.6 0.2 0.019 14.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN92119.1 - 0.032 14.3 0.6 0.36 10.9 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KZN92119.1 - 0.046 12.9 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KZN92119.1 - 0.1 12.2 0.0 0.73 9.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF498 PF04430.9 KZN92120.1 - 6.8e-26 89.9 0.0 1e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 KZN92121.1 - 1.5e-110 369.8 0.0 1.7e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KZN92121.1 - 0.0034 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SecE PF00584.15 KZN92121.1 - 0.21 11.1 0.2 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex SET PF00856.23 KZN92123.1 - 2.6e-13 50.5 0.2 4.7e-12 46.5 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 KZN92123.1 - 1.8e-11 43.4 1.6 4.1e-08 32.7 0.1 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KZN92123.1 - 1.6e-08 33.8 5.2 0.04 13.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KZN92123.1 - 2.9e-06 26.6 3.2 0.00039 19.8 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92123.1 - 0.00045 20.6 0.1 4.2 8.2 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KZN92123.1 - 0.0019 17.9 0.1 0.046 13.5 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92123.1 - 0.0036 16.9 0.3 4.3 7.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.1 KZN92123.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 Outer membrane lipoprotein Apc3 PF12895.2 KZN92123.1 - 0.097 12.8 0.2 0.93 9.6 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KZN92123.1 - 10 6.9 8.5 21 5.9 0.0 4.0 4 1 0 5 5 5 0 Tetratricopeptide repeat Clr5 PF14420.1 KZN92124.1 - 7.4e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain NPP PF08384.5 KZN92124.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region Methyltransf_23 PF13489.1 KZN92127.1 - 5.1e-16 58.7 0.2 1e-15 57.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN92127.1 - 1.8e-08 34.9 0.0 1.2e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN92127.1 - 0.00027 21.3 0.0 0.004 17.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN92127.1 - 0.00094 18.2 0.0 0.0026 16.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 KZN92127.1 - 0.0017 18.7 0.0 0.0075 16.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92127.1 - 0.0018 17.8 0.0 0.0064 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN92127.1 - 0.0052 16.8 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN92127.1 - 0.015 14.6 0.0 0.087 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KZN92127.1 - 0.08 12.0 0.0 3.4 6.7 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KZN92127.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_16 PF00722.16 KZN92128.1 - 1.4e-43 148.3 9.3 2.5e-43 147.5 6.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KZN92128.1 - 0.48 10.4 15.1 1.1 9.3 10.5 1.6 1 0 0 1 1 1 0 Chitin recognition protein cNMP_binding PF00027.24 KZN92131.1 - 3.5e-38 129.2 0.0 6.4e-21 73.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 KZN92131.1 - 5.8e-15 53.6 4.0 2.2 8.5 0.0 9.8 10 0 0 10 10 10 3 Leucine Rich repeat F-box-like PF12937.2 KZN92131.1 - 8.9e-07 28.5 0.2 2.7e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 KZN92131.1 - 3.2e-06 26.4 4.1 20 5.7 0.1 7.9 7 2 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.1 KZN92131.1 - 5.5e-06 26.0 0.1 0.088 12.5 0.3 4.3 4 0 0 4 4 4 1 Leucine rich repeat F-box PF00646.28 KZN92131.1 - 2.5e-05 23.8 0.8 0.00012 21.6 0.6 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KZN92131.1 - 0.00013 21.4 1.1 1.6 8.4 0.0 5.1 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KZN92131.1 - 0.015 15.3 9.6 50 4.7 0.1 7.0 8 0 0 8 8 8 0 Leucine rich repeat Ste50p-SAM PF09235.5 KZN92131.1 - 0.5 10.4 4.1 4.5 7.3 0.3 3.4 4 0 0 4 4 4 0 Ste50p, sterile alpha motif Tim17 PF02466.14 KZN92132.1 - 0.00062 19.8 1.4 0.0011 19.0 1.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Kinesin PF00225.18 KZN92134.1 - 1.4e-114 382.3 0.0 2.1e-114 381.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 KZN92134.1 - 0.034 14.0 0.1 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PMSR PF01625.16 KZN92135.1 - 7.2e-59 198.1 0.1 8.3e-59 197.9 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 KZN92135.1 - 0.073 12.3 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 KaiA domain Abhydrolase_6 PF12697.2 KZN92136.1 - 1.9e-21 77.0 0.0 4.1e-21 75.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN92136.1 - 1.3e-10 41.2 0.1 1.6e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN92136.1 - 1.5e-09 37.7 0.0 3.9e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN92136.1 - 3.2e-05 23.3 0.0 0.049 12.9 0.0 2.9 2 1 1 3 3 3 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KZN92136.1 - 6.4e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 KZN92136.1 - 0.0021 16.9 0.5 0.0048 15.8 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 KZN92136.1 - 0.02 14.5 0.3 0.072 12.7 0.1 1.9 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KZN92136.1 - 0.097 12.2 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold TRP PF06011.7 KZN92138.1 - 1.5e-119 399.4 27.2 1.9e-119 399.1 18.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KZN92138.1 - 4.8e-33 114.1 0.2 7.9e-33 113.4 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Sugar_tr PF00083.19 KZN92139.1 - 1e-127 426.4 27.3 1.2e-127 426.2 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92139.1 - 2.1e-22 79.3 44.2 1.2e-17 63.6 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 KZN92140.1 - 3.5e-63 209.9 5.1 2e-18 66.4 0.0 5.5 3 2 4 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN92140.1 - 1.6e-47 157.0 17.5 2e-06 27.2 0.0 9.2 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KZN92140.1 - 1.6e-36 123.5 8.7 0.00016 21.8 0.2 8.8 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN92140.1 - 1.6e-33 114.4 4.1 1.1e-08 35.3 0.0 7.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN92140.1 - 2.4e-27 92.2 7.5 0.0065 16.5 0.0 9.8 10 0 0 10 10 10 7 Ankyrin repeat NACHT PF05729.7 KZN92140.1 - 0.0068 16.0 0.2 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_13 PF13166.1 KZN92140.1 - 0.024 13.1 1.9 0.04 12.4 1.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2120 PF09893.4 KZN92140.1 - 0.14 12.0 0.1 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) APG5 PF04106.7 KZN92141.1 - 3.3e-64 216.0 0.0 4e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SAM_2 PF07647.12 KZN92142.1 - 3.9e-10 39.4 0.0 7.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KZN92142.1 - 5.3e-09 36.1 0.1 1.7e-08 34.4 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KZN92142.1 - 4e-05 23.7 0.1 9.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Fungal_trans_2 PF11951.3 KZN92143.1 - 1.5e-85 287.1 0.0 2.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92143.1 - 4.2e-08 32.9 8.3 7.4e-08 32.1 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SHR3_chaperone PF08229.6 KZN92146.1 - 1.5e-78 262.2 0.0 1.9e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 HlyIII PF03006.15 KZN92146.1 - 0.52 9.6 6.0 0.07 12.5 1.6 1.4 2 0 0 2 2 2 0 Haemolysin-III related Arrestin_N PF00339.24 KZN92147.1 - 2.1e-15 56.8 0.0 2.6e-14 53.3 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KZN92147.1 - 9.2e-07 29.0 0.3 0.002 18.2 0.0 3.3 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.27 KZN92148.1 - 5.6e-26 89.4 18.9 9.7e-08 31.6 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat HRXXH PF13933.1 KZN92151.1 - 1e-108 362.4 0.0 1.3e-108 362.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family PDZ_1 PF12812.2 KZN92151.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 PDZ-like domain Zip PF02535.17 KZN92152.1 - 2.2e-35 122.2 19.2 2.2e-35 122.2 13.3 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Thyroglobulin_1 PF00086.13 KZN92152.1 - 2 7.8 4.7 8.7 5.7 0.0 2.9 4 0 0 4 4 4 0 Thyroglobulin type-1 repeat Acetyltransf_1 PF00583.19 KZN92153.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN92153.1 - 1.4e-06 28.3 0.0 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN92153.1 - 3.4e-05 23.9 0.0 0.0011 19.1 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN92153.1 - 0.00013 21.8 0.1 0.0014 18.4 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN92153.1 - 0.00091 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KZN92153.1 - 0.0028 17.3 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KZN92153.1 - 0.043 13.6 0.0 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KZN92156.1 - 1.2e-29 103.1 39.0 1.2e-29 103.1 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN92156.1 - 8.3e-09 34.5 39.4 1.9e-08 33.3 9.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Peptidase_S10 PF00450.17 KZN92157.1 - 3.2e-89 299.9 0.0 4.5e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 KZN92158.1 - 4.8e-28 97.8 39.8 1.9e-16 59.7 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN92158.1 - 4.9e-17 61.6 22.4 1.8e-16 59.7 15.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 KZN92159.1 - 9e-70 234.7 0.0 1.2e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92159.1 - 3.4e-32 111.5 0.0 2.1e-30 105.6 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN92159.1 - 0.0035 17.1 0.0 0.33 10.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN92159.1 - 0.087 11.7 1.4 1.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Abhydrolase_6 PF12697.2 KZN92160.1 - 2.6e-17 63.4 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN92160.1 - 3.8e-13 49.5 0.0 4.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN92160.1 - 9.8e-12 44.8 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN92160.1 - 1.1e-05 25.1 0.0 2.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 KZN92160.1 - 1.9e-05 24.4 0.0 0.019 14.6 0.1 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.16 KZN92160.1 - 0.0003 20.0 0.0 0.071 12.3 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 KZN92160.1 - 0.0018 17.7 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AurF PF11583.3 KZN92162.1 - 0.024 13.5 0.4 0.03 13.2 0.3 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF DUF4526 PF15029.1 KZN92162.1 - 0.074 12.6 0.5 0.094 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) p450 PF00067.17 KZN92163.1 - 6.7e-37 127.0 0.0 7.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KZN92164.1 - 6.7e-13 48.0 2.3 7.7e-13 47.9 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92164.1 - 5.2e-06 26.2 9.8 1e-05 25.3 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1399 PF07173.7 KZN92165.1 - 4.7e-21 75.4 2.4 1e-16 61.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) zf-C2H2_4 PF13894.1 KZN92166.1 - 0.024 14.9 1.0 0.073 13.4 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN92166.1 - 0.21 12.0 2.5 0.52 10.7 1.7 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_18 PF12847.2 KZN92169.1 - 2.1e-17 63.7 0.0 3.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92169.1 - 8.2e-12 44.9 0.0 3.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KZN92169.1 - 2.5e-10 40.2 0.0 4.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN92169.1 - 2.6e-07 31.0 0.2 5.9e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN92169.1 - 1.6e-06 28.4 2.3 1.1e-05 25.8 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN92169.1 - 1.4e-05 25.0 0.0 7.2e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KZN92169.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KZN92169.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KZN92169.1 - 0.0018 18.5 0.0 0.0063 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KZN92169.1 - 0.0027 17.0 0.0 0.0059 16.0 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 KZN92169.1 - 0.0073 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KZN92169.1 - 0.038 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RXT2_N PF08595.6 KZN92169.1 - 0.075 12.8 6.7 0.14 11.9 1.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal SDA1 PF05285.7 KZN92169.1 - 0.11 11.7 4.6 0.16 11.2 3.2 1.2 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 KZN92169.1 - 1.3 8.4 11.9 0.33 10.4 4.1 2.1 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KZN92169.1 - 4.6 7.5 16.0 7.4 6.8 8.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KZN92169.1 - 6 6.4 13.0 6.5 6.3 5.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.4 KZN92169.1 - 6.3 5.4 14.1 3 6.4 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KZN92169.1 - 7.7 5.4 8.0 9.6 5.1 3.2 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DSPc PF00782.15 KZN92170.1 - 1.7e-23 82.6 0.0 3.8e-21 75.0 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KZN92170.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4139 PF13598.1 KZN92170.1 - 1.2 8.3 8.5 0.17 11.1 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) KH_1 PF00013.24 KZN92172.1 - 5.7e-39 131.5 9.4 2.9e-15 55.6 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KZN92172.1 - 1.3e-29 101.3 11.4 4.6e-11 42.1 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KZN92172.1 - 2.9e-09 36.3 10.6 0.0022 17.4 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KZN92172.1 - 1.9e-07 30.6 5.5 0.12 12.0 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KZN92172.1 - 0.00038 20.1 3.5 0.96 9.3 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KZN92172.1 - 0.0036 16.7 0.1 0.99 8.8 0.0 3.1 3 0 0 3 3 3 1 dUTPase GARS_C PF02843.11 KZN92172.1 - 0.11 12.6 0.6 10 6.4 0.0 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ADH_N PF08240.7 KZN92173.1 - 2.2e-29 101.4 1.3 4e-29 100.5 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN92173.1 - 4.2e-20 71.6 0.0 1.1e-19 70.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KZN92173.1 - 0.00049 19.6 0.4 0.0012 18.4 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Yippee-Mis18 PF03226.9 KZN92174.1 - 8.9e-25 86.5 1.8 1e-24 86.3 1.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 KZN92174.1 - 0.026 14.5 0.7 0.3 11.1 0.0 2.2 1 1 1 2 2 2 0 HNH endonuclease DUF2039 PF10217.4 KZN92174.1 - 0.03 14.3 0.4 0.03 14.3 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 KZN92174.1 - 0.048 13.5 1.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 KZN92174.1 - 0.23 11.3 3.4 0.16 11.8 1.2 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Endonuclease_7 PF02945.10 KZN92174.1 - 0.41 10.3 2.6 0.35 10.6 0.7 1.9 1 1 1 2 2 2 0 Recombination endonuclease VII GFA PF04828.9 KZN92174.1 - 1.5 8.8 4.2 0.56 10.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.27 KZN92175.1 - 1.4e-12 46.9 11.1 0.077 12.9 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KZN92175.1 - 1.4e-05 24.6 0.0 0.11 11.8 0.0 3.3 2 1 0 2 2 2 2 PQQ-like domain Cyclin_N PF00134.18 KZN92176.1 - 2.1e-35 121.0 0.3 2.1e-35 121.0 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KZN92176.1 - 5.2e-15 55.4 1.4 1.6e-14 53.8 1.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain FLO_LFY PF01698.11 KZN92176.1 - 0.037 12.8 0.1 0.08 11.7 0.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein UvrD_C PF13361.1 KZN92178.1 - 2.5e-74 250.8 0.0 3.7e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KZN92178.1 - 2.4e-62 211.0 0.9 4.5e-60 203.5 0.1 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KZN92178.1 - 1.1e-14 54.3 0.0 4e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KZN92178.1 - 1.7e-12 46.9 0.1 3.2e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN92178.1 - 6.6e-07 29.1 0.1 0.00023 20.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 KZN92178.1 - 2.1e-06 27.2 0.0 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KZN92178.1 - 7.4e-05 22.4 0.1 0.00056 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KZN92178.1 - 0.00024 20.6 0.3 0.18 11.3 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Rrp15p PF07890.7 KZN92178.1 - 0.0017 18.3 0.1 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 Rrp15p AAA_22 PF13401.1 KZN92178.1 - 0.0029 17.7 0.7 0.35 11.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN92178.1 - 0.095 12.6 2.7 0.12 12.3 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain p450 PF00067.17 KZN92179.1 - 4.2e-60 203.5 0.0 5.6e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FmdA_AmdA PF03069.10 KZN92180.1 - 4.6e-53 180.2 0.0 1.1e-27 96.6 0.0 2.3 1 1 1 2 2 2 2 Acetamidase/Formamidase family PP2C PF00481.16 KZN92181.1 - 6.7e-42 143.6 0.0 8.5e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KZN92181.1 - 5.4e-06 25.9 0.0 2.9e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KZN92181.1 - 1.5e-05 24.8 0.1 0.03 14.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Cyt-b5 PF00173.23 KZN92182.1 - 4.2e-14 52.1 0.0 6.3e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 KZN92183.1 - 3.5e-32 110.2 0.0 4.2e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugar_tr PF00083.19 KZN92184.1 - 7.2e-50 169.8 29.1 2.4e-49 168.1 20.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92184.1 - 3.4e-15 55.6 37.6 6.1e-08 31.7 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 KZN92185.1 - 5.6e-57 193.1 9.4 6.3e-57 192.9 6.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tom37_C PF11801.3 KZN92187.1 - 4.1e-36 124.3 0.0 6.7e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KZN92187.1 - 2.3e-25 88.6 0.2 6e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein PEP_mutase PF13714.1 KZN92189.1 - 5.7e-49 166.4 0.9 6.6e-49 166.2 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KZN92189.1 - 1.2e-19 69.9 0.2 1.7e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KZN92189.1 - 0.014 14.5 0.2 0.075 12.1 0.1 2.0 1 1 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Hist_deacetyl PF00850.14 KZN92190.1 - 1.6e-76 257.5 0.2 2.4e-76 256.9 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Oxysterol_BP PF01237.13 KZN92191.1 - 4.3e-90 301.7 0.0 5.6e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3868 PF12984.2 KZN92191.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) DUF3605 PF12239.3 KZN92192.1 - 1.4e-61 206.9 0.2 1.8e-61 206.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 KZN92193.1 - 3.8e-25 88.8 0.0 7.6e-25 87.8 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Ssu72 PF04722.8 KZN92194.1 - 2.5e-82 274.9 0.0 3e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 KZN92194.1 - 0.017 14.5 3.3 0.023 14.0 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KZN92194.1 - 3.2 6.9 7.9 5.2 6.2 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF2_N PF00176.18 KZN92195.1 - 1.5e-52 178.2 0.0 2.3e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KZN92195.1 - 1.5e-26 92.0 0.8 2.5e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KZN92195.1 - 3.8e-15 55.5 0.0 3.3e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN92195.1 - 2e-05 24.4 0.0 0.00016 21.5 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNase_PH PF01138.16 KZN92196.1 - 1.1e-32 113.1 0.3 2.3e-32 112.0 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 KZN92196.1 - 0.024 15.1 3.1 0.062 13.7 2.2 1.7 1 0 0 1 1 1 0 Coiled coil Ctr PF04145.10 KZN92197.1 - 3.1e-42 144.0 0.1 8.6e-42 142.5 0.1 1.6 1 1 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KZN92197.1 - 0.005 16.3 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) DUF3123 PF11321.3 KZN92197.1 - 0.047 13.9 0.2 0.095 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Oxidored_q3 PF00499.15 KZN92197.1 - 0.27 11.0 7.2 0.52 10.0 5.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4407 PF14362.1 KZN92197.1 - 4.5 6.1 6.5 8.5 5.2 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pro_isomerase PF00160.16 KZN92198.1 - 1e-42 145.9 0.2 1.3e-42 145.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GIT_SHD PF08518.6 KZN92199.1 - 1.7e-24 84.8 3.5 3.5e-15 55.0 0.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT CENP-F_leu_zip PF10473.4 KZN92199.1 - 0.0088 15.8 26.3 0.2 11.5 9.0 2.8 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspB PF06667.7 KZN92199.1 - 0.55 10.1 6.0 0.68 9.9 0.9 3.2 1 1 1 2 2 2 0 Phage shock protein B DUF904 PF06005.7 KZN92199.1 - 2 8.7 29.9 53 4.2 0.8 4.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 KZN92199.1 - 2.1 7.3 27.9 0.016 14.2 11.4 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 KSR1-SAM PF13543.1 KZN92200.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 HD_4 PF13328.1 KZN92202.1 - 0.0028 17.3 0.1 0.0043 16.7 0.1 1.3 1 0 0 1 1 1 1 HD domain HMG-CoA_red PF00368.13 KZN92203.1 - 3.5e-154 512.9 4.9 4.5e-154 512.6 3.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KZN92203.1 - 1.8e-51 173.8 0.2 3.7e-51 172.8 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KZN92203.1 - 1.6e-13 50.3 3.8 9.1e-13 47.9 2.6 2.1 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KZN92203.1 - 4.6e-08 31.4 1.4 4.6e-08 31.4 1.0 1.4 2 0 0 2 2 2 1 Patched family DUF2304 PF10066.4 KZN92203.1 - 0.025 14.4 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) PT PF04886.7 KZN92204.1 - 0.0012 18.1 21.0 0.0013 17.9 11.0 3.3 2 0 0 2 2 2 1 PT repeat RAP1 PF07218.6 KZN92204.1 - 2.1 6.3 5.9 2.9 5.8 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SH3_1 PF00018.23 KZN92205.1 - 7.2e-11 41.3 0.1 1.6e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KZN92205.1 - 2.1e-10 40.0 0.1 4.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KZN92205.1 - 3.9e-08 32.6 0.0 7.3e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ENTH PF01417.15 KZN92206.1 - 2.5e-45 153.3 0.2 3.6e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KZN92206.1 - 0.00045 19.0 0.0 0.00066 18.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain RasGAP_C PF03836.10 KZN92207.1 - 3.7e-44 149.8 3.9 3.7e-44 149.8 2.7 2.2 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 KZN92207.1 - 2.1e-37 128.7 0.1 6.6e-37 127.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 KZN92207.1 - 5.8e-10 39.1 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 KZN92207.1 - 4.9e-08 31.9 57.6 0.75 9.6 0.0 14.4 15 0 0 15 15 15 8 IQ calmodulin-binding motif DUF952 PF06108.7 KZN92208.1 - 9.5e-25 86.2 0.0 1.2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) adh_short PF00106.20 KZN92209.1 - 3.9e-29 101.7 0.0 1.2e-28 100.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN92209.1 - 2.3e-22 79.9 0.0 2.9e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN92209.1 - 2.4e-10 40.3 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KZN92209.1 - 0.00059 19.5 0.1 0.0026 17.4 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KZN92209.1 - 0.0031 16.9 0.1 0.0056 16.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KZN92209.1 - 0.0059 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 KZN92209.1 - 0.011 15.1 0.4 0.025 13.9 0.3 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 KZN92209.1 - 0.084 12.8 0.0 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding IMPDH PF00478.20 KZN92210.1 - 1.1e-130 435.6 4.3 1.4e-130 435.2 3.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KZN92210.1 - 1.1e-17 63.5 0.0 8e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KZN92210.1 - 1.3e-06 27.8 4.5 0.0046 16.1 1.8 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KZN92210.1 - 1.2e-05 24.3 0.6 3.1e-05 23.0 0.5 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KZN92210.1 - 0.0023 17.2 3.4 0.062 12.5 2.4 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 KZN92210.1 - 0.019 14.1 0.8 0.084 12.0 0.1 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase NUDIX PF00293.23 KZN92211.1 - 1.3e-12 47.5 0.0 3.1e-10 39.8 0.0 3.1 1 1 0 1 1 1 1 NUDIX domain DUF4473 PF14747.1 KZN92211.1 - 0.041 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Ribosomal_S21e PF01249.13 KZN92212.1 - 7e-42 141.2 0.0 7.8e-42 141.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.15 KZN92213.1 - 8.1e-88 293.7 0.0 1.2e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KZN92213.1 - 4.5e-05 22.3 0.5 0.0023 16.7 0.0 3.1 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KZN92213.1 - 0.00038 20.0 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Androgen_recep PF02166.11 KZN92213.1 - 0.04 12.7 0.6 0.07 11.9 0.4 1.3 1 0 0 1 1 1 0 Androgen receptor tRNA-synt_His PF13393.1 KZN92213.1 - 0.086 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HAMP PF00672.20 KZN92214.1 - 2.3e-49 165.4 16.2 8.1e-10 38.7 0.4 6.8 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KZN92214.1 - 2e-31 107.9 0.2 7.2e-31 106.1 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN92214.1 - 1.1e-27 96.2 1.3 2e-25 88.9 0.2 3.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 KZN92214.1 - 4.5e-16 58.5 0.1 4.5e-16 58.5 0.1 4.5 6 0 0 6 6 6 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 KZN92214.1 - 0.01 14.3 28.5 0.077 11.4 2.9 4.1 1 1 2 4 4 4 3 AAA domain DUF2365 PF10157.4 KZN92214.1 - 0.01 15.7 19.5 1.6 8.5 0.0 7.0 7 1 0 8 8 8 0 Uncharacterized conserved protein (DUF2365) NOD PF06816.8 KZN92214.1 - 0.038 13.0 0.1 1.1 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein Scaffolding_pro PF11418.3 KZN92214.1 - 0.28 11.5 9.3 39 4.6 0.0 5.6 5 0 0 5 5 5 0 Phi29 scaffolding protein Pox_A_type_inc PF04508.7 KZN92214.1 - 0.41 10.5 2.9 1.1 9.1 0.1 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PilJ PF13675.1 KZN92214.1 - 1 9.6 12.3 10 6.4 0.1 6.1 4 2 2 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term NAAA-beta PF15508.1 KZN92214.1 - 1.5 9.1 6.4 18 5.7 0.1 5.2 6 1 0 6 6 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ribosomal_L24e PF01246.15 KZN92215.1 - 1.2e-25 89.1 2.9 1.2e-25 89.1 2.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DnaJ PF00226.26 KZN92216.1 - 3.8e-08 32.9 0.1 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KZN92216.1 - 5.9e-08 32.5 0.1 1.2e-07 31.6 0.1 1.6 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 KZN92216.1 - 0.073 12.4 1.0 0.073 12.4 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Fungal_trans PF04082.13 KZN92217.1 - 2.4e-29 101.9 0.1 9.7e-29 100.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92217.1 - 7.2e-10 38.6 13.1 1.2e-09 37.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAN PF11640.3 KZN92217.1 - 8.9 6.0 5.8 15 5.2 0.0 3.4 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Peptidase_M41 PF01434.13 KZN92218.1 - 2e-74 249.6 0.0 3.1e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KZN92218.1 - 1.4e-42 145.0 0.0 3e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KZN92218.1 - 6.5e-13 48.8 0.4 1.8e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 KZN92218.1 - 0.00031 20.4 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN92218.1 - 0.0012 18.9 0.1 0.22 11.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KZN92218.1 - 0.004 17.9 2.0 0.016 16.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KZN92218.1 - 0.0048 16.3 0.0 0.041 13.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KZN92218.1 - 0.0062 16.2 0.5 0.02 14.6 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KZN92218.1 - 0.0064 15.2 0.1 0.015 14.0 0.1 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KZN92218.1 - 0.0069 15.4 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KZN92218.1 - 0.014 15.3 0.4 0.22 11.5 0.1 2.6 2 1 0 3 3 3 0 AAA ATPase domain DUF1155 PF06633.6 KZN92218.1 - 0.029 13.6 0.1 0.067 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) AAA_25 PF13481.1 KZN92218.1 - 0.04 13.3 0.6 0.17 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain DUF2201_N PF13203.1 KZN92218.1 - 0.041 13.0 11.9 0.035 13.2 7.1 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain AAA_2 PF07724.9 KZN92218.1 - 0.044 13.6 0.8 0.12 12.3 0.0 2.1 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KZN92218.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 KZN92218.1 - 0.22 10.1 2.3 0.32 9.5 1.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KZN92218.1 - 0.26 9.2 10.4 0.39 8.6 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_18 PF13238.1 KZN92218.1 - 0.8 10.0 0.0 0.8 10.0 0.0 3.1 4 0 0 4 4 3 0 AAA domain DUF2146 PF10220.4 KZN92218.1 - 5.2 4.9 9.8 7.7 4.3 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1295 PF06966.7 KZN92219.1 - 1.2e-39 136.0 7.2 1.5e-39 135.6 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4181 PF13789.1 KZN92219.1 - 7.5 6.5 9.2 1.2 9.0 2.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) Topoisom_bac PF01131.15 KZN92220.1 - 8.2e-90 301.5 0.0 1e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KZN92220.1 - 2e-18 66.1 0.0 4.5e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4140 PF13600.1 KZN92221.1 - 0.12 12.7 1.4 0.32 11.4 0.2 2.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) T2SF PF00482.18 KZN92221.1 - 0.13 12.1 1.0 6.3 6.7 0.2 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Stc1 PF12898.2 KZN92222.1 - 0.081 12.9 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Stc1 domain Glyco_hydro_28 PF00295.12 KZN92224.1 - 3.9e-36 124.6 10.8 1.1e-31 110.0 4.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Glyco_hydro_7 PF00840.15 KZN92225.1 - 5.8e-215 713.6 18.0 6.7e-215 713.4 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 WD40 PF00400.27 KZN92226.1 - 6.5e-07 29.0 3.2 0.1 12.4 0.0 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat YL1 PF05764.8 KZN92226.1 - 0.7 9.4 9.6 1.1 8.7 6.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Bromodomain PF00439.20 KZN92227.1 - 1.6e-21 75.9 0.1 2.9e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KZN92227.1 - 5e-10 39.4 0.1 1e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN92227.1 - 1.8e-09 37.4 0.0 3.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KZN92227.1 - 0.064 13.4 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 KZN92229.1 - 8.2e-22 77.1 4.9 2e-21 75.9 3.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN92229.1 - 3.5e-07 30.0 0.0 8.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3969 PF13108.1 KZN92229.1 - 0.023 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Fe-ADH PF00465.14 KZN92230.1 - 5.7e-75 252.2 0.7 6.6e-75 252.0 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KZN92230.1 - 2.7e-16 59.6 0.2 3.6e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Diphthamide_syn PF01866.12 KZN92231.1 - 9.5e-53 179.4 0.0 2.4e-52 178.0 0.0 1.5 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Glyco_tranf_2_3 PF13641.1 KZN92231.1 - 0.083 12.6 0.1 1.9 8.2 0.1 2.7 2 1 1 3 3 3 0 Glycosyltransferase like family 2 AP4E_app_platf PF14807.1 KZN92233.1 - 0.05 13.8 0.5 0.059 13.5 0.3 1.1 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF543 PF04418.7 KZN92233.1 - 0.14 12.1 0.2 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Taxilin PF09728.4 KZN92233.1 - 0.25 10.3 6.8 0.25 10.4 4.7 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CS PF04969.11 KZN92234.1 - 2e-17 63.4 0.0 3.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 CS domain Zn_clus PF00172.13 KZN92235.1 - 3e-10 39.8 10.3 6e-10 38.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN92235.1 - 0.0053 15.4 0.2 0.0053 15.4 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Peripla_BP_4 PF13407.1 KZN92235.1 - 0.25 10.6 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Methyltransf_12 PF08242.7 KZN92237.1 - 1.1e-14 54.6 0.0 7.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN92237.1 - 6.6e-14 51.9 0.1 1.8e-13 50.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN92237.1 - 6.4e-11 42.6 0.0 1.8e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN92237.1 - 1.3e-08 35.4 0.0 6.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92237.1 - 5e-08 32.6 0.0 1.5e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN92237.1 - 4e-07 30.3 0.0 8.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN92237.1 - 4.3e-07 29.2 0.0 7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KZN92237.1 - 6.6e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 KZN92237.1 - 9.6e-05 21.2 0.0 0.00015 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.10 KZN92237.1 - 0.00025 20.7 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase MTS PF05175.9 KZN92237.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KZN92237.1 - 0.027 15.2 0.0 0.22 12.3 0.0 2.3 3 0 0 3 3 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KZN92237.1 - 0.038 12.9 0.0 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.1 KZN92237.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.15 KZN92238.1 - 2.3e-56 190.6 24.9 2.8e-56 190.4 17.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 KZN92238.1 - 0.0031 17.3 0.8 0.0031 17.3 0.5 2.5 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.8 KZN92238.1 - 2.4 7.0 5.5 4.8 6.0 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4131 PF13567.1 KZN92238.1 - 6.4 6.1 7.4 1.6 8.0 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FimP PF09766.4 KZN92239.1 - 2.8e-26 92.4 13.5 3.5e-26 92.1 9.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 KZN92239.1 - 8.5e-05 22.5 13.3 0.023 14.6 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 KZN92239.1 - 0.026 14.5 12.4 0.72 9.9 3.4 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil RNase_E_G PF10150.4 KZN92239.1 - 0.071 12.3 7.4 0.055 12.7 1.5 2.1 2 0 0 2 2 2 0 Ribonuclease E/G family K-box PF01486.12 KZN92239.1 - 0.087 12.6 0.6 0.087 12.6 0.4 3.3 2 2 0 2 2 2 0 K-box region CwfJ_C_1 PF04677.10 KZN92239.1 - 0.12 11.9 0.9 0.45 10.1 0.2 1.9 1 1 1 2 2 2 0 Protein similar to CwfJ C-terminus 1 DUF972 PF06156.8 KZN92239.1 - 0.43 10.9 8.3 3.9 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2353 PF09789.4 KZN92239.1 - 0.46 9.6 10.8 0.86 8.7 7.5 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) PIG-S PF10510.4 KZN92240.1 - 2.1e-180 600.8 0.0 2.4e-180 600.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1517 PF07466.6 KZN92241.1 - 0.079 11.9 1.2 0.12 11.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Sporozoite_P67 PF05642.6 KZN92241.1 - 5.8 4.6 10.1 7.5 4.2 7.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sod_Fe_C PF02777.13 KZN92242.1 - 1.2e-13 50.7 0.1 4e-08 33.0 0.2 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KZN92242.1 - 0.021 15.0 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Polyketide_cyc PF03364.15 KZN92243.1 - 3.7e-23 81.9 0.0 1.6e-22 79.9 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KZN92243.1 - 0.00033 20.8 0.1 0.0026 17.9 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.13 KZN92244.1 - 1.2e-14 53.7 1.9 2.2e-14 52.9 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92244.1 - 9e-06 25.4 13.2 9e-06 25.4 9.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KZN92246.1 - 5.8e-51 172.9 0.0 6.5e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 KZN92247.1 - 2.3e-65 220.6 0.0 3.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN92247.1 - 4.1e-08 34.0 0.0 7.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 KZN92248.1 - 8.8e-45 153.2 0.0 1.1e-44 152.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KZN92248.1 - 1.4e-07 30.9 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KZN92248.1 - 8.9e-07 27.9 0.0 1.9e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KZN92248.1 - 3.1e-05 22.4 0.0 4.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KZN92248.1 - 0.00082 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.19 KZN92249.1 - 2e-35 121.8 21.2 3.9e-35 120.9 14.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KZN92249.1 - 3.9e-23 82.2 1.9 5.2e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KZN92249.1 - 1.2e-09 38.5 0.1 1.7e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KZN92249.1 - 2.5e-05 23.4 27.2 2.5e-05 23.4 18.9 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 KZN92249.1 - 0.00011 22.0 22.1 0.034 14.2 1.8 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 KZN92249.1 - 0.0017 17.8 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KZN92249.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KZN92249.1 - 0.028 13.4 0.0 0.63 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KZN92249.1 - 0.035 13.6 0.2 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KZN92249.1 - 0.056 12.6 0.8 1.1 8.4 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KZN92249.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.8 KZN92249.1 - 0.17 12.0 36.7 0.025 14.7 8.7 4.5 4 0 0 4 4 4 0 EGF-like domain AAA_23 PF13476.1 KZN92249.1 - 0.35 11.1 1.6 0.38 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain Laminin_EGF PF00053.19 KZN92249.1 - 2.6 8.0 29.1 0.92 9.4 5.4 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Cornichon PF03311.9 KZN92250.1 - 4.9e-53 178.6 13.1 5.5e-53 178.4 9.1 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KZN92250.1 - 0.046 13.3 0.2 0.095 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 KZN92250.1 - 8.6 5.8 8.4 19 4.6 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) WD40 PF00400.27 KZN92251.1 - 1.4e-43 145.2 6.9 3.4e-11 42.5 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KZN92251.1 - 0.00063 19.2 0.0 0.0018 17.7 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain Tox-PL PF15644.1 KZN92251.1 - 0.97 10.1 3.5 71 4.1 0.2 4.4 4 2 0 4 4 4 0 Papain fold toxin 1 FAD_binding_3 PF01494.14 KZN92252.1 - 1.4e-17 63.8 0.0 2.9e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN92252.1 - 5.7e-05 23.4 0.0 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN92252.1 - 0.0006 18.7 0.0 0.0016 17.4 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KZN92252.1 - 0.00067 19.6 0.2 0.0027 17.6 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KZN92252.1 - 0.0016 17.0 0.1 0.0024 16.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KZN92252.1 - 0.002 18.0 0.0 0.0059 16.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN92252.1 - 0.0021 17.0 0.1 0.005 15.7 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN92252.1 - 0.014 14.4 1.1 0.066 12.2 0.8 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KZN92252.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KZN92252.1 - 0.17 10.7 0.1 0.36 9.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KZN92252.1 - 0.19 11.3 0.7 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 KZN92253.1 - 2.7e-44 151.2 0.0 3.3e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KZN92253.1 - 0.0016 18.2 5.7 0.0016 18.2 4.0 2.3 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.11 KZN92254.1 - 4.5e-46 157.1 53.3 4.5e-46 157.1 36.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN92254.1 - 1.3e-14 53.6 10.2 1.3e-14 53.6 7.1 3.6 3 1 0 4 4 4 1 Sugar (and other) transporter DUF2752 PF10825.3 KZN92254.1 - 0.022 14.7 1.3 0.022 14.7 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) EF-hand_1 PF00036.27 KZN92255.1 - 1.3e-12 46.0 2.8 1.9e-05 23.6 0.2 3.3 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 KZN92255.1 - 1.3e-11 43.8 4.8 2.3e-11 43.0 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 KZN92255.1 - 6.6e-10 38.0 2.5 0.00013 21.5 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KZN92255.1 - 2.4e-09 37.2 4.9 4.5e-09 36.3 1.7 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KZN92255.1 - 8.2e-08 31.7 3.0 0.012 15.1 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KZN92255.1 - 0.00067 18.8 5.3 0.25 10.7 0.2 3.2 3 0 0 3 3 3 2 EF hand DUF4614 PF15391.1 KZN92255.1 - 0.92 9.2 2.8 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) UNC-93 PF05978.11 KZN92256.1 - 2.2e-15 56.4 2.4 2.2e-15 56.4 1.6 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KZN92256.1 - 1.8e-14 53.2 20.0 1.8e-14 53.2 13.9 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KZN92256.1 - 0.081 10.9 0.0 0.081 10.9 0.0 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 KZN92256.1 - 1 7.8 20.8 0.01 14.4 3.8 2.9 2 1 1 3 3 3 0 Sugar (and other) transporter 3Beta_HSD PF01073.14 KZN92257.1 - 1.6e-54 184.4 0.0 2e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN92257.1 - 5.6e-42 143.7 0.0 6.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN92257.1 - 1e-17 63.8 0.0 1.8e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KZN92257.1 - 3e-16 59.1 0.0 4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN92257.1 - 3.4e-13 50.0 0.0 4.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN92257.1 - 9.9e-12 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN92257.1 - 5e-10 38.7 0.0 3.5e-09 35.9 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KZN92257.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KZN92257.1 - 8.4e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KZN92257.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KZN92257.1 - 0.00087 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KZN92257.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.8 KZN92257.1 - 0.021 14.0 0.0 0.049 12.8 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 KZN92257.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.1 KZN92257.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ribosomal_S8 PF00410.14 KZN92260.1 - 6.2e-25 87.5 0.0 9.6e-25 86.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 KZN92263.1 - 1.5e-97 326.7 0.0 2.7e-97 325.8 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.5 KZN92264.1 - 3.7e-29 100.4 0.3 1.3e-28 98.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DUF2945 PF11160.3 KZN92265.1 - 0.086 12.6 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) Beta-lactamase PF00144.19 KZN92266.1 - 7.2e-60 202.7 0.2 8.9e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KZN92266.1 - 0.0036 16.6 0.3 0.056 12.7 0.1 2.1 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.1 KZN92266.1 - 0.072 12.5 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase enzyme family CENP-F_leu_zip PF10473.4 KZN92267.1 - 5.8e-05 22.9 35.2 0.019 14.8 7.4 4.6 3 1 0 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KZN92267.1 - 0.00022 20.8 0.2 0.00022 20.8 0.2 4.1 3 1 0 4 4 4 2 IncA protein ADIP PF11559.3 KZN92267.1 - 0.004 17.0 6.2 0.004 17.0 4.3 4.4 2 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding Sec3_C_2 PF15278.1 KZN92267.1 - 0.022 14.8 0.1 0.077 13.1 0.0 2.0 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Reo_sigmaC PF04582.7 KZN92267.1 - 0.36 9.9 10.0 0.35 9.9 1.7 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Tup_N PF08581.5 KZN92267.1 - 0.4 10.9 16.9 1.2 9.3 0.5 4.5 4 1 0 4 4 4 0 Tup N-terminal Fib_alpha PF08702.5 KZN92267.1 - 0.44 10.6 18.2 0.61 10.2 1.4 3.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Taxilin PF09728.4 KZN92267.1 - 5.2 6.0 27.7 2.2 7.2 13.4 2.7 2 1 0 2 2 2 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.7 KZN92267.1 - 5.7 6.6 30.4 1.9 8.2 6.7 4.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 KZN92267.1 - 6.5 6.1 33.4 0.86 9.0 14.5 3.3 2 1 0 2 2 2 0 Intermediate filament protein DUF3506 PF12014.3 KZN92268.1 - 2.2e-47 160.2 0.0 3.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KZN92268.1 - 5.6e-09 35.5 0.1 9.8e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN92268.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KZN92268.1 - 0.029 14.1 0.1 0.077 12.7 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain 2OG-FeII_Oxy PF03171.15 KZN92269.1 - 1e-21 77.0 0.0 2.4e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KZN92269.1 - 1.4e-16 61.0 0.0 2.9e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF1748 PF08520.5 KZN92273.1 - 2.7e-18 65.3 0.0 3e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 KZN92274.1 - 2.7e-171 568.8 2.9 3.4e-171 568.5 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KZN92274.1 - 1.7e-32 111.4 0.0 4.7e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KZN92274.1 - 0.00011 21.1 0.5 0.00028 19.8 0.4 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KZN92274.1 - 0.032 13.1 0.1 0.63 8.8 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Methyltransf_2 PF00891.13 KZN92275.1 - 2.1e-34 118.8 0.0 3.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase HTH_27 PF13463.1 KZN92275.1 - 0.0058 16.9 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.1 KZN92275.1 - 0.03 13.7 0.0 0.097 12.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KZN92275.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 KZN92275.1 - 0.11 12.5 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PY_rept_46 PF09689.5 KZN92276.1 - 0.094 13.0 0.7 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) Arif-1 PF06770.6 KZN92276.1 - 0.55 9.5 6.3 1.4 8.2 4.3 1.7 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) PIP5K PF01504.13 KZN92277.1 - 4.7e-58 196.2 0.0 9.3e-58 195.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KZN92277.1 - 2.3e-25 89.1 0.0 3.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KZN92277.1 - 1.4e-14 53.7 5.7 1.4e-14 53.7 3.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger SUR7 PF06687.7 KZN92279.1 - 2.9e-50 170.7 13.0 3.5e-50 170.5 9.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4191 PF13829.1 KZN92279.1 - 0.5 9.4 3.7 0.75 8.8 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Dala_Dala_lig_C PF07478.8 KZN92282.1 - 1.3e-27 96.5 0.0 2.2e-27 95.7 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KZN92282.1 - 8.1e-12 45.2 0.0 2.3e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN92282.1 - 1.8e-07 30.2 0.0 3.2e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 KZN92282.1 - 0.00034 20.2 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 KZN92282.1 - 0.0004 20.2 0.1 0.0008 19.3 0.1 1.6 1 1 0 1 1 1 1 ATP-grasp domain Peptidase_C70 PF12385.3 KZN92282.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 ATP-grasp PF02222.17 KZN92282.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Cellulase PF00150.13 KZN92283.1 - 2.4e-55 187.7 2.6 3.2e-55 187.3 1.8 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL PF00657.17 KZN92284.1 - 8.6e-13 48.6 0.5 1e-12 48.4 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.27 KZN92285.1 - 3.6e-23 80.5 28.3 2.1e-09 36.8 0.8 10.4 10 1 0 10 10 10 6 WD domain, G-beta repeat XPG_N PF00752.12 KZN92286.1 - 3e-35 120.5 0.2 1.9e-34 117.9 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KZN92286.1 - 8e-25 86.7 1.0 1.7e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 KZN92286.1 - 5.1e-05 23.4 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 KZN92286.1 - 0.0024 17.2 0.1 0.017 14.6 0.1 2.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Transposase_20 PF02371.11 KZN92286.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family TSC22 PF01166.13 KZN92288.1 - 0.0073 16.2 0.2 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 KZN92288.1 - 0.02 14.6 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pil1 PF13805.1 KZN92289.1 - 6.8e-153 507.5 0.4 8.2e-153 507.2 0.3 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KZN92289.1 - 0.14 11.4 4.6 0.19 11.0 0.5 2.2 1 1 1 2 2 2 0 FAM92 protein bZIP_2 PF07716.10 KZN92290.1 - 2.3e-13 49.7 12.7 3.9e-13 48.9 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KZN92290.1 - 2.4e-05 24.2 14.6 5.1e-05 23.1 9.9 1.7 1 1 1 2 2 2 2 bZIP transcription factor Herpes_BLRF2 PF05812.7 KZN92290.1 - 0.00091 19.0 0.6 0.00091 19.0 0.4 1.9 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 KZN92290.1 - 0.0092 16.3 0.6 0.015 15.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) CCDC144C PF14915.1 KZN92290.1 - 0.018 13.9 4.4 0.024 13.5 3.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF3552 PF12072.3 KZN92290.1 - 0.13 11.5 8.1 0.16 11.1 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fungal_trans PF04082.13 KZN92291.1 - 1.1e-24 86.7 0.4 2e-24 85.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92291.1 - 0.00022 21.0 10.7 0.00037 20.3 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc7_N PF15402.1 KZN92292.1 - 0 1024.8 74.8 5.2e-192 640.3 28.8 3.1 2 1 2 4 4 4 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KZN92292.1 - 6.9e-121 402.8 4.8 1.4e-120 401.8 3.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 KZN92292.1 - 3.9 5.2 5.4 6.5 4.4 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S17 PF00366.15 KZN92293.1 - 5e-30 103.3 1.5 8.2e-30 102.6 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 ANTH PF07651.11 KZN92295.1 - 2.5e-58 197.0 0.0 3.3e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KZN92295.1 - 1.2e-07 31.5 0.0 9.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.3 KZN92296.1 - 8.5e-13 47.6 0.0 3.1e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain CAP_N PF01213.14 KZN92296.1 - 2.2 7.5 14.0 0.34 10.1 7.2 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Grp1_Fun34_YaaH PF01184.14 KZN92297.1 - 6.1e-86 287.0 17.4 7.6e-86 286.7 12.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Oxidored_FMN PF00724.15 KZN92298.1 - 2.8e-97 325.8 0.0 3.3e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2011 PF09428.5 KZN92299.1 - 5.9 6.7 26.6 0.048 13.5 1.2 5.0 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF2011) WD40 PF00400.27 KZN92301.1 - 9e-31 104.6 9.5 9.8e-08 31.5 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KZN92301.1 - 9.5e-06 25.4 0.5 0.022 14.5 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 KZN92301.1 - 0.00034 20.0 0.2 0.00034 20.0 0.2 2.9 3 0 0 3 3 3 1 HIRA B motif PD40 PF07676.7 KZN92301.1 - 0.02 14.5 2.3 6.3 6.5 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_transf_20 PF00982.16 KZN92302.1 - 7.2e-140 466.6 0.0 1.3e-139 465.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KZN92302.1 - 1e-28 99.8 0.0 2.2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Rad4 PF03835.10 KZN92303.1 - 4.6e-14 52.0 6.7 7.6e-14 51.3 4.6 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KZN92303.1 - 1.9e-11 44.1 2.2 4.7e-11 42.8 1.5 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glyco_hydro_71 PF03659.9 KZN92305.1 - 3.2e-133 443.9 0.8 4.1e-133 443.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KZN92305.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) EIF_2_alpha PF07541.7 KZN92305.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Memo PF01875.12 KZN92306.1 - 9.3e-67 224.7 0.0 1.1e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Presenilin PF01080.12 KZN92307.1 - 1.4 7.6 4.2 1.8 7.2 2.9 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.10 KZN92307.1 - 2.6 7.2 7.5 3.2 6.9 5.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tuberculin PF12198.3 KZN92307.1 - 3.9 7.4 5.8 4 7.4 1.0 2.2 2 0 0 2 2 2 0 Theoretical tuberculin protein LSM PF01423.17 KZN92308.1 - 5.8e-05 22.5 0.0 7.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KZN92308.1 - 0.008 16.0 0.0 0.01 15.7 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Metallophos PF00149.23 KZN92309.1 - 6.5e-42 143.1 0.2 8.7e-42 142.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AOX PF01786.12 KZN92310.1 - 5.1e-85 284.0 0.1 6.5e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF3435 PF11917.3 KZN92311.1 - 2.7e-74 250.3 0.6 4.3e-74 249.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF883 PF05957.8 KZN92311.1 - 0.032 14.6 1.0 0.032 14.6 0.7 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phe_tRNA-synt_N PF02912.13 KZN92311.1 - 0.035 13.8 1.0 0.099 12.3 0.7 1.8 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Adeno_PVIII PF01310.13 KZN92316.1 - 0.042 13.6 0.4 0.089 12.5 0.2 1.5 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII APH PF01636.18 KZN92318.1 - 2.9e-06 27.1 0.2 0.0014 18.4 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KZN92318.1 - 0.0026 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN92318.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CENP-R PF06729.7 KZN92319.1 - 0.13 11.8 0.2 0.13 11.8 0.1 3.3 4 0 0 4 4 4 0 Kinetochore component, CENP-R NUDIX PF00293.23 KZN92321.1 - 6.4e-07 29.0 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain APH PF01636.18 KZN92323.1 - 1.9e-16 60.5 0.0 3.7e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN92323.1 - 8e-07 28.8 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN92323.1 - 0.0085 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KZN92323.1 - 0.025 13.9 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KZN92323.1 - 0.053 12.6 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase HMG_box PF00505.14 KZN92324.1 - 1.4e-12 47.7 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Sensor PF13796.1 KZN92326.1 - 1.4 8.5 12.6 0.65 9.5 0.7 3.0 1 1 2 3 3 3 0 Putative sensor CENP-F_leu_zip PF10473.4 KZN92327.1 - 0.024 14.5 3.0 0.024 14.5 2.1 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KZN92327.1 - 0.12 11.3 7.2 0.17 10.8 5.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KZN92327.1 - 0.56 10.3 5.3 0.78 9.8 3.1 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.4 KZN92327.1 - 0.74 8.0 8.3 0.92 7.7 5.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 KZN92327.1 - 1.9 8.8 6.2 4.1 7.8 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 KZN92327.1 - 3 7.7 12.2 0.29 11.0 4.5 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 KZN92327.1 - 7.1 6.8 10.0 25 5.1 4.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) BRE1 PF08647.6 KZN92327.1 - 7.3 6.6 12.3 6 6.9 3.7 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.9 KZN92327.1 - 9.2 5.8 9.9 0.86 9.1 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-RING_2 PF13639.1 KZN92329.1 - 8.9e-05 22.2 6.1 0.00024 20.8 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN92329.1 - 0.00013 21.9 5.0 0.00036 20.5 3.5 1.8 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 KZN92329.1 - 0.0017 17.9 3.4 0.0048 16.5 2.3 1.8 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 KZN92329.1 - 0.0097 15.5 2.5 0.021 14.5 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN92329.1 - 0.077 12.8 9.7 0.26 11.1 2.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KZN92329.1 - 2.6 8.1 14.0 0.072 13.1 4.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN92329.1 - 3.3 7.8 8.9 0.36 10.9 2.4 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger Pkinase PF00069.20 KZN92330.1 - 0.00072 18.7 0.0 0.0014 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92330.1 - 0.075 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 KZN92331.1 - 8.9e-33 112.5 4.3 1e-12 48.2 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN92331.1 - 4.3e-26 89.3 0.3 6.4e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KZN92331.1 - 3.5e-19 68.7 4.6 1.4e-05 25.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN92331.1 - 5.2e-16 57.1 0.7 0.00023 21.1 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KZN92331.1 - 5.2e-14 51.9 2.4 0.00024 21.2 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DMPK_coil PF08826.5 KZN92332.1 - 0.0018 18.1 2.2 0.1 12.5 0.1 3.3 2 1 1 3 3 3 1 DMPK coiled coil domain like ADIP PF11559.3 KZN92332.1 - 0.0029 17.5 1.1 0.0046 16.8 0.7 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KZN92332.1 - 0.0059 16.0 0.8 0.01 15.2 0.2 1.7 1 1 0 1 1 1 1 Septum formation initiator Jnk-SapK_ap_N PF09744.4 KZN92332.1 - 0.0083 16.1 0.9 0.011 15.7 0.6 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF812 PF05667.6 KZN92332.1 - 0.0086 14.6 0.2 0.0096 14.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF972 PF06156.8 KZN92332.1 - 0.016 15.5 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Occludin_ELL PF07303.8 KZN92332.1 - 0.016 15.9 0.3 0.043 14.5 0.1 1.8 2 1 0 2 2 2 0 Occludin homology domain ATG16 PF08614.6 KZN92332.1 - 0.018 14.8 2.0 0.027 14.3 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.16 KZN92332.1 - 0.02 14.3 0.5 0.03 13.8 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein KLRAQ PF10205.4 KZN92332.1 - 0.055 13.5 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Rootletin PF15035.1 KZN92332.1 - 0.11 12.4 2.3 0.18 11.7 1.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.2 KZN92332.1 - 0.12 12.1 2.7 0.33 10.8 1.0 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF4164 PF13747.1 KZN92332.1 - 0.29 11.3 2.9 6.9 6.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Mto2_bdg PF12808.2 KZN92332.1 - 0.32 11.1 2.0 5.5 7.1 0.3 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PaaA_PaaC PF05138.7 KZN92333.1 - 0.05 12.5 0.1 0.06 12.2 0.1 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF904 PF06005.7 KZN92334.1 - 0.0052 17.0 1.5 0.0052 17.0 1.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF904) DivIC PF04977.10 KZN92334.1 - 0.019 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF2031 PF09592.5 KZN92334.1 - 0.07 12.2 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) IncA PF04156.9 KZN92335.1 - 0.11 12.1 4.1 0.14 11.7 2.8 1.2 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 KZN92335.1 - 0.12 12.4 4.2 0.11 12.5 1.8 1.6 1 1 1 2 2 2 0 DivIVA protein AIG1 PF04548.11 KZN92335.1 - 0.17 10.9 1.5 0.22 10.6 1.1 1.2 1 0 0 1 1 1 0 AIG1 family NYD-SP28_assoc PF14775.1 KZN92335.1 - 0.66 9.7 8.0 17 5.2 2.8 3.1 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF904 PF06005.7 KZN92335.1 - 1.7 8.9 8.9 4.4 7.6 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KZN92335.1 - 2.2 8.6 6.5 7.4 6.9 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) FAD_binding_8 PF08022.7 KZN92336.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain Ferric_reduct PF01794.14 KZN92336.1 - 0.9 9.6 14.3 2.3 8.3 9.9 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component F-box-like PF12937.2 KZN92337.1 - 0.0011 18.7 4.7 0.0011 18.6 1.3 2.5 2 1 0 2 2 2 1 F-box-like Glyco_hydro_18 PF00704.23 KZN92341.1 - 1.7e-80 271.0 6.1 1.5e-79 267.9 4.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 QueF_N PF14819.1 KZN92345.1 - 0.018 15.0 0.1 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF676 PF05057.9 KZN92346.1 - 0.0014 17.9 0.1 0.016 14.4 0.1 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KZN92346.1 - 0.0088 15.9 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dicty_REP PF05086.7 KZN92346.1 - 0.025 12.3 1.9 0.035 11.8 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_1 PF00561.15 KZN92346.1 - 0.027 14.0 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4418 PF14387.1 KZN92347.1 - 0.11 12.2 0.5 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DDE_1 PF03184.14 KZN92348.1 - 2.4e-36 124.9 0.0 3.2e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_10 PF13374.1 KZN92350.1 - 3.1e-269 862.6 48.9 5.7e-14 51.5 0.2 22.7 22 0 0 22 22 22 22 Tetratricopeptide repeat TPR_12 PF13424.1 KZN92350.1 - 1.2e-247 800.5 34.2 8.2e-22 76.9 0.3 13.5 6 3 8 15 15 15 15 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92350.1 - 1e-108 346.7 44.5 5.3e-05 22.7 0.1 23.3 23 0 0 23 23 22 21 Tetratricopeptide repeat TPR_1 PF00515.23 KZN92350.1 - 2.3e-99 321.3 39.1 2.5e-05 23.6 0.0 22.4 22 0 0 22 22 22 21 Tetratricopeptide repeat TPR_11 PF13414.1 KZN92350.1 - 6.9e-84 275.4 59.4 1.3e-09 37.5 0.1 15.3 4 3 14 18 18 18 18 TPR repeat TPR_16 PF13432.1 KZN92350.1 - 6.7e-67 220.9 26.9 2e-06 28.3 0.3 14.9 2 1 16 20 20 20 19 Tetratricopeptide repeat TPR_2 PF07719.12 KZN92350.1 - 5.3e-62 200.8 39.5 0.02 14.7 0.0 22.4 22 0 0 22 22 22 17 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92350.1 - 2.4e-60 195.7 0.1 0.51 10.6 0.0 21.6 21 0 0 21 21 21 12 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92350.1 - 6.9e-45 151.2 10.6 0.0027 17.9 0.1 17.1 5 3 15 20 20 20 16 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92350.1 - 1.7e-43 143.0 34.3 0.48 11.2 0.0 23.6 21 2 3 24 24 24 9 Tetratricopeptide repeat TPR_4 PF07721.9 KZN92350.1 - 3.6e-43 141.5 0.0 2.8 8.6 0.0 22.3 22 0 0 22 22 22 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92350.1 - 3.1e-34 114.1 47.8 0.92 9.4 0.0 21.5 21 0 0 21 21 21 7 Tetratricopeptide repeat Apc3 PF12895.2 KZN92350.1 - 1.6e-30 105.0 0.0 0.012 15.7 0.0 10.3 2 1 10 13 13 13 11 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KZN92350.1 - 6e-26 88.5 13.2 5.7 7.1 0.0 20.3 21 0 0 21 21 21 0 PPR repeat DUF1925 PF09094.6 KZN92350.1 - 3.3e-13 49.4 27.2 40 4.2 0.0 18.2 11 6 8 19 19 19 0 Domain of unknown function (DUF1925) TPR_21 PF09976.4 KZN92350.1 - 3.3e-12 46.5 20.0 2.5 8.0 0.0 14.7 4 4 10 15 15 15 1 Tetratricopeptide repeat nec1 PF10379.4 KZN92350.1 - 8.2e-11 41.5 9.3 22 4.2 0.0 14.0 1 1 18 20 20 20 0 Virulence protein nec1 TPR_3 PF07720.7 KZN92350.1 - 5.2e-10 38.9 22.7 35 4.3 0.0 18.5 21 0 0 21 21 21 0 Tetratricopeptide repeat FTCD PF02971.9 KZN92350.1 - 5.5e-09 35.7 0.6 21 4.7 0.0 10.0 5 2 6 12 12 12 0 Formiminotransferase domain Rab5-bind PF09311.6 KZN92350.1 - 1.4e-07 31.5 24.6 5.6 6.8 0.1 9.9 2 2 7 11 11 11 0 Rabaptin-like protein DUF2670 PF10875.3 KZN92350.1 - 7.6e-07 29.2 1.4 33 4.4 0.0 10.2 3 2 10 15 15 14 0 Protein of unknown function (DUF2670) Atu4866 PF11512.3 KZN92350.1 - 2.9e-06 26.9 66.7 16 5.2 0.0 19.9 9 5 13 22 22 22 0 Agrobacterium tumefaciens protein Atu4866 DUF676 PF05057.9 KZN92350.1 - 0.00038 19.7 0.1 0.0011 18.3 0.0 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 KZN92350.1 - 0.0017 18.4 0.0 0.011 15.8 0.0 2.5 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 KZN92350.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN92350.1 - 0.016 14.8 0.0 0.12 11.9 0.0 2.4 3 0 0 3 3 3 0 PGAP1-like protein NB-ARC PF00931.17 KZN92350.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain HDOD PF08668.7 KZN92350.1 - 0.047 12.9 0.1 0.44 9.7 0.0 2.8 2 0 0 2 2 1 0 HDOD domain NPV_P10 PF05531.7 KZN92351.1 - 0.067 13.4 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribonucleas_3_3 PF14622.1 KZN92352.1 - 4.1e-13 49.4 0.0 4.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KZN92352.1 - 1.8e-12 47.7 0.0 4.4e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain DUF3723 PF12520.3 KZN92353.1 - 3.8e-54 184.0 0.0 3.1e-51 174.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) F-box-like PF12937.2 KZN92356.1 - 0.0011 18.6 4.7 0.0011 18.6 1.3 2.5 2 1 0 2 2 2 1 F-box-like DUF63 PF01889.12 KZN92357.1 - 0.13 12.3 3.2 0.077 13.0 0.9 1.5 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 Ferric_reduct PF01794.14 KZN92357.1 - 0.24 11.4 14.5 0.89 9.6 10.0 2.0 1 1 0 1 1 1 0 Ferric reductase like transmembrane component YlqD PF11068.3 KZN92358.1 - 0.19 11.7 4.1 8.4 6.4 0.0 1.8 1 1 0 1 1 1 0 YlqD protein Cep57_CLD_2 PF14197.1 KZN92358.1 - 0.22 11.4 9.2 0.89 9.5 5.7 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 KZN92358.1 - 0.38 10.2 5.4 2.8 7.4 3.0 2.3 1 1 1 2 2 2 0 Septum formation initiator IncA PF04156.9 KZN92358.1 - 0.39 10.2 8.6 0.55 9.7 5.9 1.3 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 KZN92358.1 - 0.48 10.7 10.9 8.4 6.7 7.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TBPIP PF07106.8 KZN92358.1 - 0.5 9.8 5.3 0.5 9.9 2.9 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 KZN92358.1 - 0.54 10.1 7.5 0.87 9.4 5.2 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DEP PF00610.16 KZN92359.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2064 PF09837.4 KZN92359.1 - 0.048 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF904 PF06005.7 KZN92360.1 - 0.0052 17.0 1.5 0.0052 17.0 1.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF904) DivIC PF04977.10 KZN92360.1 - 0.019 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF2031 PF09592.5 KZN92360.1 - 0.07 12.2 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) PaaA_PaaC PF05138.7 KZN92361.1 - 0.05 12.5 0.1 0.06 12.2 0.1 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DMPK_coil PF08826.5 KZN92362.1 - 0.0018 18.1 2.2 0.1 12.5 0.1 3.3 2 1 1 3 3 3 1 DMPK coiled coil domain like ADIP PF11559.3 KZN92362.1 - 0.0029 17.5 1.1 0.0046 16.8 0.7 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KZN92362.1 - 0.0059 16.0 0.8 0.01 15.2 0.2 1.7 1 1 0 1 1 1 1 Septum formation initiator Jnk-SapK_ap_N PF09744.4 KZN92362.1 - 0.0083 16.1 0.9 0.011 15.7 0.6 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF812 PF05667.6 KZN92362.1 - 0.0086 14.6 0.2 0.0096 14.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF972 PF06156.8 KZN92362.1 - 0.016 15.5 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Occludin_ELL PF07303.8 KZN92362.1 - 0.016 15.9 0.3 0.043 14.5 0.1 1.8 2 1 0 2 2 2 0 Occludin homology domain ATG16 PF08614.6 KZN92362.1 - 0.018 14.8 2.0 0.027 14.3 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.16 KZN92362.1 - 0.02 14.3 0.5 0.03 13.8 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein KLRAQ PF10205.4 KZN92362.1 - 0.055 13.5 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Rootletin PF15035.1 KZN92362.1 - 0.11 12.4 2.3 0.18 11.7 1.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.2 KZN92362.1 - 0.12 12.1 2.7 0.33 10.8 1.0 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF4164 PF13747.1 KZN92362.1 - 0.29 11.3 2.9 6.9 6.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Mto2_bdg PF12808.2 KZN92362.1 - 0.32 11.1 2.0 5.5 7.1 0.3 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ank_2 PF12796.2 KZN92363.1 - 8.9e-33 112.5 4.3 1e-12 48.2 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN92363.1 - 4.3e-26 89.3 0.3 6.4e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KZN92363.1 - 3.5e-19 68.7 4.6 1.4e-05 25.4 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN92363.1 - 5.2e-16 57.1 0.7 0.00023 21.1 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KZN92363.1 - 5.2e-14 51.9 2.4 0.00024 21.2 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.20 KZN92364.1 - 0.00072 18.7 0.0 0.0014 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92364.1 - 0.075 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase zf-RING_2 PF13639.1 KZN92365.1 - 8.9e-05 22.2 6.1 0.00024 20.8 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN92365.1 - 0.00013 21.9 5.0 0.00036 20.5 3.5 1.8 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 KZN92365.1 - 0.0017 17.9 3.4 0.0048 16.5 2.3 1.8 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 KZN92365.1 - 0.0097 15.5 2.5 0.021 14.5 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KZN92365.1 - 0.077 12.8 9.7 0.26 11.1 2.8 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KZN92365.1 - 2.6 8.1 14.0 0.072 13.1 4.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KZN92365.1 - 3.3 7.8 8.9 0.36 10.9 2.4 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger CENP-F_leu_zip PF10473.4 KZN92367.1 - 0.016 15.1 0.7 0.016 15.1 0.5 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KZN92367.1 - 0.024 13.6 6.1 0.032 13.2 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3373 PF11853.3 KZN92367.1 - 0.028 12.9 1.1 0.036 12.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Suppressor_APC PF11414.3 KZN92367.1 - 0.14 11.9 2.4 0.28 10.9 1.7 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein BRE1 PF08647.6 KZN92367.1 - 0.4 10.6 7.0 0.38 10.7 0.7 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 KZN92367.1 - 0.62 9.9 11.6 0.048 13.5 3.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KZN92367.1 - 0.86 9.7 5.9 0.23 11.5 2.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 KZN92367.1 - 1.6 8.7 9.1 0.23 11.4 3.2 1.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PIF1 PF05970.9 KZN92368.1 - 5.5e-21 74.9 0.2 5.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.1 KZN92368.1 - 5.2e-11 42.6 0.0 9.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 KZN92368.1 - 9e-11 41.7 0.0 5.4e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN92368.1 - 0.0016 18.1 0.1 0.0054 16.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KZN92368.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MC1 PF05854.6 KZN92368.1 - 0.25 11.3 0.0 0.57 10.1 0.0 1.5 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 FMN_red PF03358.10 KZN92369.1 - 2.5e-24 85.5 0.0 3.7e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KZN92369.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Cyclin PF08613.6 KZN92370.1 - 1.2e-28 100.4 0.0 1.8e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN92370.1 - 8.4e-05 22.1 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SBF PF01758.11 KZN92371.1 - 1.1e-50 171.6 11.1 1.1e-50 171.6 7.7 2.5 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF3671 PF12420.3 KZN92371.1 - 0.69 9.9 6.3 2.9 7.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function LMWPc PF01451.16 KZN92372.1 - 4.1e-30 104.9 0.0 4.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF3485 PF11984.3 KZN92373.1 - 0.0023 17.0 1.1 0.0034 16.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3485) TPR_12 PF13424.1 KZN92374.1 - 2.8e-101 331.5 16.8 4.1e-19 68.2 0.0 6.2 2 2 5 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 KZN92374.1 - 9.2e-95 308.2 26.3 5.2e-11 42.1 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.23 KZN92374.1 - 1e-34 116.6 4.6 0.00074 19.0 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92374.1 - 2.9e-34 114.1 19.6 0.0036 16.9 0.0 10.5 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 KZN92374.1 - 7.3e-32 108.8 7.4 5.4e-07 29.1 0.0 6.5 3 2 4 7 7 7 6 TPR repeat TPR_16 PF13432.1 KZN92374.1 - 5.4e-24 84.2 15.0 2.2e-05 24.9 0.2 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN92374.1 - 4.9e-18 63.5 15.6 0.17 11.8 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92374.1 - 3e-14 53.0 2.6 0.13 12.6 0.1 7.6 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92374.1 - 4.8e-14 50.9 7.4 0.74 9.7 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92374.1 - 6.6e-14 51.1 20.3 0.5 11.1 0.1 10.9 8 3 3 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92374.1 - 5.8e-13 47.9 0.0 0.94 9.8 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KZN92374.1 - 2.4e-11 42.9 0.0 30 5.4 0.0 9.5 9 0 0 9 9 9 0 Tetratricopeptide repeat FTCD PF02971.9 KZN92374.1 - 7.4e-10 38.6 0.0 11 5.6 0.0 7.0 2 1 5 7 7 7 0 Formiminotransferase domain Apc3 PF12895.2 KZN92374.1 - 2.7e-08 33.8 0.0 0.39 10.8 0.0 4.5 1 1 5 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 DUF1925 PF09094.6 KZN92374.1 - 3.8e-05 23.6 0.5 55 3.8 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF1925) DUF676 PF05057.9 KZN92374.1 - 4.5e-05 22.8 0.1 0.00012 21.5 0.1 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 KZN92374.1 - 0.00023 20.1 0.0 0.00037 19.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PPR PF01535.15 KZN92374.1 - 0.0005 19.8 3.9 50 4.1 0.0 7.1 8 0 0 8 8 8 0 PPR repeat Abhydrolase_6 PF12697.2 KZN92374.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KZN92374.1 - 0.0051 16.9 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KZN92374.1 - 0.011 15.3 0.0 0.077 12.5 0.0 2.3 3 0 0 3 3 3 0 PGAP1-like protein NapD PF03927.8 KZN92374.1 - 0.012 15.4 0.0 70 3.3 0.0 4.3 3 0 0 3 3 3 0 NapD protein Rab5-bind PF09311.6 KZN92374.1 - 0.021 14.7 5.2 11 5.8 1.2 4.2 1 1 2 3 3 3 0 Rabaptin-like protein DUF1203 PF06718.6 KZN92374.1 - 0.1 12.4 0.0 18 5.1 0.0 3.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1203) TPR_6 PF13174.1 KZN92374.1 - 0.12 12.8 4.4 3.8e+02 1.9 0.0 7.4 9 0 0 9 9 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KZN92374.1 - 0.15 12.0 4.1 1.1e+02 2.6 0.1 5.3 4 3 0 4 4 4 0 Tetratricopeptide repeat DUF4404 PF14357.1 KZN92374.1 - 3.2 8.2 14.9 32 5.0 0.1 6.6 6 2 2 8 8 7 0 Domain of unknown function (DUF4404) EPV_E5 PF08135.6 KZN92375.1 - 0.16 11.9 6.3 0.058 13.3 1.2 2.3 2 0 0 2 2 2 0 Major transforming protein E5 family DDE_1 PF03184.14 KZN92376.1 - 1.6e-45 154.8 0.0 2.4e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease gag_pre-integrs PF13976.1 KZN92377.1 - 6.7e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain TPR_12 PF13424.1 KZN92378.1 - 1.1e-176 573.1 39.2 6.2e-22 77.3 0.3 7.8 2 1 8 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 KZN92378.1 - 1e-141 457.4 32.1 9e-15 54.0 0.1 12.1 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_11 PF13414.1 KZN92378.1 - 2.1e-68 225.8 48.9 1.3e-11 43.9 0.5 7.2 1 1 9 10 10 10 10 TPR repeat TPR_1 PF00515.23 KZN92378.1 - 6.5e-60 196.4 38.6 1.3e-06 27.7 0.2 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92378.1 - 1.1e-50 165.4 32.3 0.00014 21.3 0.1 12.3 12 0 0 12 12 11 11 Tetratricopeptide repeat TPR_2 PF07719.12 KZN92378.1 - 3.5e-40 132.6 41.2 7e-05 22.4 0.1 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 KZN92378.1 - 1e-36 124.8 33.9 7.3e-09 36.0 0.5 7.7 3 2 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92378.1 - 1.3e-30 102.8 24.1 0.0023 17.5 0.1 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92378.1 - 3.2e-30 101.7 3.4 0.18 12.0 0.0 11.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_4 PF07721.9 KZN92378.1 - 1.5e-29 99.3 0.0 0.09 13.2 0.0 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92378.1 - 3.3e-29 98.7 28.5 0.013 16.1 0.0 12.3 11 1 1 12 12 11 7 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92378.1 - 7.6e-27 93.4 21.0 2.4e-05 24.5 0.2 8.2 2 2 7 9 9 9 9 Tetratricopeptide repeat Apc3 PF12895.2 KZN92378.1 - 1.7e-23 82.5 1.4 2.3e-06 27.6 0.3 5.4 1 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KZN92378.1 - 1.5e-15 55.9 7.2 4.4 7.5 0.0 10.1 10 0 0 10 10 10 0 PPR repeat TPR_6 PF13174.1 KZN92378.1 - 1.2e-08 34.8 37.2 0.23 12.0 0.1 10.4 11 0 0 11 11 9 3 Tetratricopeptide repeat DUF1925 PF09094.6 KZN92378.1 - 2.6e-08 33.7 12.3 20 5.2 0.0 9.8 8 1 2 10 10 10 0 Domain of unknown function (DUF1925) FTCD PF02971.9 KZN92378.1 - 2.6e-06 27.1 3.2 9.6 5.8 0.0 7.2 2 1 6 8 8 8 0 Formiminotransferase domain NACHT PF05729.7 KZN92378.1 - 1.5e-05 24.7 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Rab5-bind PF09311.6 KZN92378.1 - 7.2e-05 22.7 13.4 1 9.1 0.4 5.6 2 2 3 6 6 6 2 Rabaptin-like protein NB-ARC PF00931.17 KZN92378.1 - 0.00055 18.8 0.0 0.0013 17.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 KZN92378.1 - 0.00065 19.0 0.1 0.0036 16.6 0.1 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_5 PF12688.2 KZN92378.1 - 0.0024 17.9 19.4 0.092 12.7 0.3 5.3 2 1 4 6 6 6 1 Tetratrico peptide repeat MIT PF04212.13 KZN92378.1 - 0.0025 17.6 24.5 17 5.3 0.1 8.8 7 2 2 9 9 9 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.2 KZN92378.1 - 0.0026 17.6 16.7 23 4.7 0.2 7.9 3 2 4 8 8 8 0 Domain of Unknown Function (DUF3856) 14-3-3 PF00244.15 KZN92378.1 - 0.0034 16.5 1.7 1.9 7.5 0.0 5.0 3 2 2 6 6 6 1 14-3-3 protein AAA_22 PF13401.1 KZN92378.1 - 0.0045 17.1 0.0 0.032 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 KZN92378.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_3 PF07720.7 KZN92378.1 - 0.017 14.9 19.4 3.2 7.6 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_21 PF09976.4 KZN92378.1 - 0.024 14.5 23.8 3.7 7.4 1.0 7.8 3 3 2 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KZN92378.1 - 0.044 13.0 13.5 25 4.1 0.0 7.3 10 0 0 10 10 8 0 SHNi-TPR PGAP1 PF07819.8 KZN92378.1 - 0.047 13.2 0.0 0.23 11.0 0.0 2.1 3 0 0 3 3 2 0 PGAP1-like protein HDOD PF08668.7 KZN92378.1 - 0.06 12.6 0.1 0.34 10.1 0.0 2.4 1 0 0 1 1 1 0 HDOD domain nec1 PF10379.4 KZN92378.1 - 0.073 12.3 0.0 94 2.2 0.0 4.3 3 2 1 4 4 4 0 Virulence protein nec1 Abhydrolase_1 PF00561.15 KZN92378.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mad3_BUB1_I PF08311.7 KZN92378.1 - 1.3 8.7 7.7 15 5.3 0.1 5.6 6 0 0 6 6 6 0 Mad3/BUB1 homology region 1 Claudin_2 PF13903.1 KZN92379.1 - 0.03 14.0 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Colicin_V PF02674.11 KZN92379.1 - 0.081 12.7 2.3 0.14 12.0 1.6 1.3 1 0 0 1 1 1 0 Colicin V production protein DDE_1 PF03184.14 KZN92380.1 - 3.6e-48 163.5 0.0 5.8e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KZN92380.1 - 2.5e-08 33.5 0.0 6.7e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF676 PF05057.9 KZN92381.1 - 3.1e-05 23.3 0.1 9.1e-05 21.8 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KZN92381.1 - 0.00097 19.0 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN92381.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 KZN92381.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LPP PF04728.8 KZN92382.1 - 0.0074 16.0 0.1 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF4618 PF15397.1 KZN92382.1 - 0.069 12.4 0.1 0.091 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HAUS5 PF14817.1 KZN92383.1 - 0.00072 18.2 4.6 0.00076 18.1 3.2 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 IncA PF04156.9 KZN92383.1 - 0.0085 15.7 4.2 0.011 15.3 2.9 1.3 1 0 0 1 1 1 1 IncA protein DUF4618 PF15397.1 KZN92383.1 - 0.011 15.1 6.3 0.053 12.8 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Seryl_tRNA_N PF02403.17 KZN92383.1 - 0.014 15.3 5.4 0.028 14.4 3.4 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Peripla_BP_2 PF01497.13 KZN92383.1 - 0.016 14.3 0.7 0.019 14.0 0.5 1.2 1 0 0 1 1 1 0 Periplasmic binding protein DUF3186 PF11382.3 KZN92383.1 - 0.02 14.0 2.6 0.027 13.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Spectrin PF00435.16 KZN92383.1 - 0.021 15.0 1.4 0.021 15.0 0.9 2.1 1 1 1 2 2 2 0 Spectrin repeat T4SS PF07996.6 KZN92383.1 - 0.023 14.5 6.2 0.76 9.6 0.9 2.1 1 1 1 2 2 2 0 Type IV secretion system proteins Tropomyosin_1 PF12718.2 KZN92383.1 - 0.024 14.4 11.1 0.049 13.4 7.7 1.4 1 1 0 1 1 1 0 Tropomyosin like DUF2982 PF11201.3 KZN92383.1 - 0.029 13.7 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) Tektin PF03148.9 KZN92383.1 - 0.03 12.8 7.2 0.067 11.7 4.7 1.6 1 1 1 2 2 2 0 Tektin family Afi1 PF07792.7 KZN92383.1 - 0.03 14.3 2.1 0.041 13.9 1.4 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CorA PF01544.13 KZN92383.1 - 0.035 13.1 0.6 0.042 12.8 0.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 KZN92383.1 - 0.043 13.6 2.1 0.074 12.9 1.5 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 KZN92383.1 - 0.046 13.5 7.7 0.068 13.0 5.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KZN92383.1 - 0.054 13.3 1.7 2.3 8.1 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IFT46_B_C PF12317.3 KZN92383.1 - 0.065 12.5 0.9 0.086 12.1 0.6 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Vps23_core PF09454.5 KZN92383.1 - 0.075 12.6 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Vps23 core domain LUC7 PF03194.10 KZN92383.1 - 0.1 12.1 4.3 0.12 11.8 3.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Syntaxin-6_N PF09177.6 KZN92383.1 - 0.1 12.9 6.7 1.6 9.1 4.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal bZIP_Maf PF03131.12 KZN92383.1 - 0.14 12.4 6.5 1 9.7 0.7 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor COG2 PF06148.6 KZN92383.1 - 0.16 11.8 3.4 0.74 9.6 0.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 KZN92383.1 - 0.16 9.7 3.9 0.19 9.5 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG5 PF10392.4 KZN92383.1 - 0.19 11.7 2.7 0.25 11.2 1.9 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 GAT PF03127.9 KZN92383.1 - 0.2 11.6 4.1 1.2 9.1 2.8 2.1 1 1 0 1 1 1 0 GAT domain Lge1 PF11488.3 KZN92383.1 - 0.22 11.7 2.8 0.52 10.5 2.0 1.7 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF848 PF05852.6 KZN92383.1 - 0.24 11.2 6.4 0.36 10.6 4.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) WXG100 PF06013.7 KZN92383.1 - 0.24 11.4 3.2 4.7 7.2 0.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Macoilin PF09726.4 KZN92383.1 - 0.24 9.6 5.0 0.27 9.4 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein SICA_alpha PF12887.2 KZN92383.1 - 0.26 11.0 2.9 4.1 7.1 0.0 2.1 1 1 1 2 2 2 0 SICA extracellular alpha domain DUF2802 PF10975.3 KZN92383.1 - 0.27 10.9 3.1 0.67 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) AKNA PF12443.3 KZN92383.1 - 0.3 11.1 6.0 0.11 12.5 0.5 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.10 KZN92383.1 - 0.36 10.3 8.6 0.92 9.0 1.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Bap31 PF05529.7 KZN92383.1 - 0.37 10.2 4.1 0.55 9.6 2.8 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2205 PF10224.4 KZN92383.1 - 0.43 10.1 5.4 0.23 11.0 0.9 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) TBPIP PF07106.8 KZN92383.1 - 0.43 10.0 7.4 0.82 9.2 5.1 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cauli_AT PF03233.8 KZN92383.1 - 0.44 10.2 3.6 0.52 9.9 0.5 1.9 1 1 1 2 2 2 0 Aphid transmission protein APG6 PF04111.7 KZN92383.1 - 0.49 9.3 7.1 0.59 9.1 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KZN92383.1 - 0.54 10.6 8.4 0.31 11.4 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 KZN92383.1 - 0.54 10.3 6.3 3.2 7.8 1.1 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil Ax_dynein_light PF10211.4 KZN92383.1 - 0.56 10.0 8.6 0.25 11.1 3.7 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4094 PF13334.1 KZN92383.1 - 0.57 10.6 3.5 5.7 7.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PspB PF06667.7 KZN92383.1 - 0.57 10.1 3.0 4.1 7.4 0.2 2.2 2 0 0 2 2 2 0 Phage shock protein B NPV_P10 PF05531.7 KZN92383.1 - 0.85 9.9 4.1 2.3 8.5 0.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KZN92383.1 - 1.4 8.5 8.3 0.31 10.6 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 KZN92383.1 - 1.5 8.5 9.4 4.9 6.9 6.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GP41 PF00517.12 KZN92383.1 - 1.6 8.2 5.0 2.1 7.8 0.7 2.0 1 1 1 2 2 2 0 Retroviral envelope protein DivIVA PF05103.8 KZN92383.1 - 2.3 8.2 11.2 0.24 11.4 1.8 2.2 1 1 1 2 2 2 0 DivIVA protein Utp21 PF04192.7 KZN92383.1 - 2.5 7.1 8.3 3.5 6.6 1.4 2.2 1 1 1 2 2 2 0 Utp21 specific WD40 associated putative domain bZIP_1 PF00170.16 KZN92383.1 - 2.6 8.0 8.0 2.7 8.0 0.4 3.1 1 1 2 3 3 3 0 bZIP transcription factor EMP24_GP25L PF01105.19 KZN92383.1 - 3.2 7.4 6.6 3.2 7.4 0.6 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.10 KZN92383.1 - 3.6 7.4 12.7 6.8 6.6 1.8 3.2 2 1 1 3 3 3 0 Basic region leucine zipper FlaG PF03646.10 KZN92383.1 - 4.1 7.6 8.9 1.2 9.3 1.6 2.3 1 1 1 2 2 2 0 FlaG protein Striatin PF08232.7 KZN92383.1 - 4.8 7.5 8.8 1.5 9.1 0.5 2.3 2 1 0 2 2 2 0 Striatin family Spc24 PF08286.6 KZN92383.1 - 5.5 6.7 10.4 1.2 8.8 2.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 XhlA PF10779.4 KZN92383.1 - 6.1 6.8 9.3 3.2 7.7 3.1 2.2 1 1 2 3 3 3 0 Haemolysin XhlA Mnd1 PF03962.10 KZN92383.1 - 7.1 6.2 11.3 23 4.5 7.2 1.9 1 1 0 1 1 1 0 Mnd1 family EST1_DNA_bind PF10373.4 KZN92385.1 - 2.5e-05 23.6 0.0 5.1e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF3435 PF11917.3 KZN92390.1 - 4.8e-107 358.2 0.5 6.4e-107 357.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) IncA PF04156.9 KZN92390.1 - 0.31 10.6 3.9 0.53 9.8 2.7 1.3 1 0 0 1 1 1 0 IncA protein zf-PARP PF00645.13 KZN92391.1 - 0.00071 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region E1-E2_ATPase PF00122.15 KZN92392.1 - 2.3e-44 151.1 0.0 7.2e-44 149.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN92392.1 - 2.6e-36 126.0 0.0 5.9e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN92392.1 - 4.6e-28 97.1 1.0 2.3e-08 34.0 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KZN92392.1 - 2.9e-16 60.2 0.0 6.5e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN92392.1 - 0.00078 19.0 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN92392.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Zip PF02535.17 KZN92393.1 - 1.6e-48 165.4 3.6 2.5e-48 164.7 2.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Cu-oxidase_2 PF07731.9 KZN92394.1 - 1.2e-42 144.7 5.5 7.5e-36 122.6 0.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN92394.1 - 1.8e-40 137.3 6.1 2.5e-40 136.8 0.1 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 KZN92394.1 - 3.8e-22 78.8 0.0 5.7e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN92395.1 - 1.8e-10 40.5 0.1 3.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN92395.1 - 0.0003 20.3 0.1 0.00036 20.0 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase DUF3723 PF12520.3 KZN92396.1 - 1.8e-188 627.1 0.5 2.7e-188 626.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Pkinase PF00069.20 KZN92397.1 - 0.049 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain FAD_binding_8 PF08022.7 KZN92399.1 - 8.7e-11 41.6 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KZN92399.1 - 7e-10 39.0 7.2 7e-10 39.0 5.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KZN92399.1 - 8.2e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PE PF00934.15 KZN92401.1 - 0.031 14.3 0.1 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 PE family DUF759 PF05537.6 KZN92401.1 - 0.033 12.9 0.2 3.3 6.3 0.0 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) NUDIX PF00293.23 KZN92401.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain APH PF01636.18 KZN92405.1 - 2e-15 57.2 0.0 4.5e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN92405.1 - 0.021 13.4 0.0 0.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) APH PF01636.18 KZN92407.1 - 1e-05 25.3 0.1 0.0025 17.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN92407.1 - 0.00035 20.1 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KZN92407.1 - 0.00092 18.3 0.2 0.0015 17.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN92407.1 - 0.0034 16.5 0.1 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2841 PF11001.3 KZN92409.1 - 2.2e-20 72.8 0.0 4.2e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Glyco_hydro_71 PF03659.9 KZN92410.1 - 2.9e-143 477.0 3.3 3.4e-143 476.7 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 KZN92410.1 - 0.014 15.0 0.4 0.028 14.1 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) CENP-F_leu_zip PF10473.4 KZN92413.1 - 0.015 15.1 0.7 0.015 15.1 0.5 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KZN92413.1 - 0.024 13.7 6.1 0.031 13.3 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3373 PF11853.3 KZN92413.1 - 0.028 12.9 1.2 0.036 12.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Suppressor_APC PF11414.3 KZN92413.1 - 0.14 11.9 2.4 0.28 11.0 1.7 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein BRE1 PF08647.6 KZN92413.1 - 0.39 10.7 7.0 0.37 10.8 0.7 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 KZN92413.1 - 0.6 9.9 11.6 0.047 13.6 3.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 KZN92413.1 - 0.84 9.7 5.9 0.23 11.5 2.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 KZN92413.1 - 2.6 8.0 9.6 0.3 11.0 3.2 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 KZN92414.1 - 0.001 18.9 23.8 0.021 14.6 8.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KZN92414.1 - 0.0018 17.5 4.2 0.0018 17.5 2.9 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein EzrA PF06160.7 KZN92414.1 - 0.0064 14.7 17.4 0.018 13.2 12.0 1.7 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Mnd1 PF03962.10 KZN92414.1 - 0.0079 15.8 10.4 0.0079 15.8 7.2 2.6 2 1 1 3 3 3 1 Mnd1 family CorA PF01544.13 KZN92414.1 - 0.0081 15.2 7.8 0.016 14.2 5.1 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TACC PF05010.9 KZN92414.1 - 0.019 14.7 15.0 0.056 13.2 10.4 1.8 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) V_ATPase_I PF01496.14 KZN92414.1 - 0.081 10.7 11.8 0.045 11.6 6.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 KZN92414.1 - 0.082 12.7 3.4 0.11 12.3 0.9 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_27 PF13514.1 KZN92414.1 - 0.15 9.6 19.7 0.36 8.4 13.6 1.6 1 1 0 1 1 1 0 AAA domain DUF812 PF05667.6 KZN92414.1 - 0.24 9.8 19.7 0.38 9.2 12.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4201 PF13870.1 KZN92414.1 - 0.48 9.8 21.2 1.2 8.5 3.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PEP-utilisers_N PF05524.8 KZN92414.1 - 0.93 9.3 9.7 0.059 13.1 1.2 2.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal AAA_13 PF13166.1 KZN92414.1 - 1.1 7.6 20.2 1.3 7.3 13.0 1.8 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 KZN92414.1 - 1.1 8.1 22.3 18 4.1 15.5 2.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 KZN92414.1 - 2.3 6.7 25.0 0.24 10.0 4.6 2.8 3 1 1 4 4 4 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KZN92414.1 - 3.9 7.5 15.8 0.15 12.1 5.7 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HAP1_N PF04849.8 KZN92414.1 - 4.3 6.1 26.4 1.3 7.9 6.1 2.4 1 1 0 2 2 2 0 HAP1 N-terminal conserved region IncA PF04156.9 KZN92414.1 - 4.6 6.7 33.5 0.71 9.4 10.5 2.6 2 1 1 3 3 3 0 IncA protein DUF3450 PF11932.3 KZN92414.1 - 8.6 5.5 21.8 2.8 7.1 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.3 KZN92414.1 - 9.2 6.1 22.9 0.86 9.4 4.8 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding 4HBT PF03061.17 KZN92417.1 - 0.00047 20.2 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily Ank_2 PF12796.2 KZN92418.1 - 1e-67 224.4 11.8 1e-10 41.7 0.1 6.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KZN92418.1 - 1.1e-50 169.1 9.2 7.8e-11 42.1 0.0 8.5 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 KZN92418.1 - 8.5e-45 148.4 11.3 7.4e-05 22.3 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KZN92418.1 - 1.5e-42 142.6 14.0 7.3e-09 35.6 0.1 9.9 4 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN92418.1 - 2.3e-37 123.2 7.8 0.004 17.2 0.0 11.3 11 0 0 11 11 11 8 Ankyrin repeat Myb_DNA-binding PF00249.26 KZN92419.1 - 5.4e-05 23.1 0.1 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KZN92419.1 - 6.5e-05 22.9 0.2 0.00023 21.2 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pro_dh PF01619.13 KZN92420.1 - 3.4e-43 147.8 0.1 4.5e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 KZN92420.1 - 0.0043 16.3 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 KZN92421.1 - 1.1e-96 324.1 19.7 1.3e-96 324.0 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92421.1 - 2.2e-29 102.2 52.7 1.1e-21 76.9 19.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN92421.1 - 0.082 12.7 0.0 0.082 12.7 0.0 2.8 3 0 0 3 3 3 0 MFS_1 like family PsbW PF07123.7 KZN92422.1 - 0.0059 16.6 2.8 0.041 13.9 1.9 2.2 1 1 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) DUF2568 PF10823.3 KZN92422.1 - 0.98 9.6 4.8 0.16 12.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Aldedh PF00171.17 KZN92423.1 - 1.8e-94 316.7 0.0 2.3e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1308 PF07000.6 KZN92423.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) LuxC PF05893.9 KZN92423.1 - 0.16 10.6 0.1 1.4 7.5 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA reductase (LuxC) DAO PF01266.19 KZN92424.1 - 5.8e-40 137.2 0.0 6.8e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN92424.1 - 2.6e-05 24.1 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN92424.1 - 0.0094 14.8 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN92424.1 - 0.014 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN92424.1 - 0.018 14.9 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN92424.1 - 0.022 13.8 0.0 0.097 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 KZN92424.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 KZN92424.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 KZN92425.1 - 1.9e-09 36.7 0.4 5.4e-09 35.2 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PGAMP PF07644.6 KZN92425.1 - 0.065 12.9 0.9 3.3 7.5 0.4 2.5 2 0 0 2 2 2 0 Planctomycete PGAMP RabGAP-TBC PF00566.13 KZN92428.1 - 3.2e-34 118.2 0.4 5.1e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain vATP-synt_E PF01991.13 KZN92428.1 - 0.099 11.9 0.9 1.6 7.9 0.2 2.2 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Pkinase PF00069.20 KZN92429.1 - 3.7e-58 196.7 0.0 5.8e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92429.1 - 5.1e-21 74.9 0.0 7.8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92429.1 - 1.6e-05 24.0 0.0 3.9e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN92429.1 - 9.6e-05 22.2 0.2 0.0044 16.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN92429.1 - 0.00034 19.7 0.1 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KZN92429.1 - 0.01 15.2 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 KZN92430.1 - 1.8e-11 43.5 0.0 6.9e-11 41.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KZN92430.1 - 1.4e-10 40.1 7.5 0.27 11.4 0.0 7.8 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.28 KZN92430.1 - 5.2e-09 35.5 0.0 5.6e-08 32.2 0.0 2.9 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KZN92430.1 - 7.9e-06 25.3 7.5 0.0038 16.8 0.0 5.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KZN92430.1 - 0.021 14.7 13.9 2.2 8.6 0.2 7.1 5 3 0 5 5 5 0 Leucine Rich Repeat PRANC PF09372.5 KZN92430.1 - 0.14 12.1 0.1 0.98 9.4 0.0 2.4 2 0 0 2 2 2 0 PRANC domain LRR_7 PF13504.1 KZN92430.1 - 0.17 12.2 6.5 81 4.1 0.1 5.9 6 0 0 6 6 6 0 Leucine rich repeat zf-C3HC4_2 PF13923.1 KZN92431.1 - 1.2 9.1 10.7 0.15 12.0 2.2 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2361 PF10153.4 KZN92432.1 - 4.4e-38 129.9 7.9 4.4e-38 129.9 5.5 3.0 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) Zip PF02535.17 KZN92432.1 - 9.2 5.1 5.2 15 4.4 3.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M55 PF04951.8 KZN92433.1 - 0.31 10.1 4.7 0.5 9.5 3.2 1.3 1 0 0 1 1 1 0 D-aminopeptidase PTS_2-RNA PF01885.11 KZN92434.1 - 1.2e-73 246.3 0.0 1.6e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KZN92434.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 La domain AreA_N PF07573.6 KZN92434.1 - 5.5 7.6 6.5 92 3.7 4.5 2.5 1 1 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus Dioxygenase_C PF00775.16 KZN92435.1 - 8.2e-52 175.1 0.0 1.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KZN92435.1 - 4.6e-12 45.7 0.1 7.4e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KZN92435.1 - 3.9e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KZN92435.1 - 0.017 15.1 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) Cna_B PF05738.8 KZN92435.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Cna protein B-type domain Abhydrolase_6 PF12697.2 KZN92436.1 - 3.3e-33 115.4 0.0 4.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN92436.1 - 3e-18 66.2 0.0 8.1e-13 48.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN92436.1 - 9.6e-17 61.0 0.1 2.9e-16 59.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KZN92436.1 - 5.8e-06 25.0 0.0 7.2e-06 24.6 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 KZN92436.1 - 4.7e-05 22.9 0.1 0.0043 16.5 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KZN92436.1 - 0.0013 17.9 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KZN92436.1 - 0.002 17.8 0.1 0.0047 16.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 KZN92436.1 - 0.0043 16.6 0.2 0.096 12.2 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 KZN92436.1 - 0.0067 16.0 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 KZN92436.1 - 0.016 14.5 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.15 KZN92436.1 - 0.05 13.0 0.0 0.098 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF915 PF06028.6 KZN92436.1 - 0.063 12.3 0.2 0.2 10.7 0.0 1.8 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 KZN92436.1 - 0.13 11.5 0.1 0.53 9.5 0.1 2.0 2 1 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.10 KZN92436.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Aldo_ket_red PF00248.16 KZN92437.1 - 1.7e-42 145.2 0.0 2.2e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 KZN92438.1 - 3.2e-44 149.6 0.0 5e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KZN92438.1 - 1.6e-20 73.4 0.0 2.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KZN92438.1 - 5.7e-20 72.0 0.0 8.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 MFS_1 PF07690.11 KZN92440.1 - 2.9e-22 78.8 48.6 6e-20 71.2 22.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.16 KZN92441.1 - 1.7e-31 107.9 21.4 5.7e-17 61.3 5.5 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 KZN92441.1 - 0.036 13.6 0.9 0.036 13.6 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF4234 PF14018.1 KZN92441.1 - 0.57 9.9 4.5 5.4 6.8 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Flavi_NS4A PF01350.12 KZN92441.1 - 1.6 8.2 4.9 0.52 9.8 1.4 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Peptidase_C14 PF00656.17 KZN92442.1 - 2.2e-73 247.0 0.0 2.9e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KZN92442.1 - 0.068 13.0 0.5 0.25 11.1 0.0 2.2 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.19 KZN92443.1 - 5.8e-140 467.1 2.1 6.6e-140 466.9 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 KZN92443.1 - 0.077 12.8 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-H2C2 PF09337.5 KZN92444.1 - 6.4e-22 76.6 4.2 1.2e-21 75.8 2.9 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KZN92444.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KZN92444.1 - 0.0028 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN92444.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN92444.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN92444.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PAT1 PF09770.4 KZN92444.1 - 3.3 5.8 12.8 4 5.5 8.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FlxA PF14282.1 KZN92444.1 - 9.5 6.2 6.6 2.4 8.1 2.1 1.7 2 0 0 2 2 2 0 FlxA-like protein LANC_like PF05147.8 KZN92445.1 - 7e-24 84.0 0.0 1.2e-22 80.0 0.0 2.3 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein F-box-like PF12937.2 KZN92446.1 - 3.3e-05 23.5 0.3 8.7e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KZN92446.1 - 0.0029 17.5 0.1 29 5.1 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat F-box PF00646.28 KZN92446.1 - 0.014 15.0 0.9 0.047 13.3 0.1 2.3 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.28 KZN92446.1 - 0.037 14.0 1.9 18 5.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1635 PF07795.6 KZN92446.1 - 0.04 13.3 0.8 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Ribosomal_S26e PF01283.14 KZN92447.1 - 6.4e-52 174.6 6.6 7.4e-52 174.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 KZN92447.1 - 0.02 15.2 1.0 0.59 10.5 0.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 KZN92447.1 - 0.07 13.4 0.3 9 6.7 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KZN92447.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF1101 PF06503.6 KZN92447.1 - 0.14 10.9 0.1 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) CBS PF00571.23 KZN92448.1 - 3.2e-42 142.0 7.5 4.4e-10 39.1 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KZN92448.1 - 5.5e-10 38.7 0.0 1.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 PB1 domain HEAT_EZ PF13513.1 KZN92449.1 - 1.6e-21 76.1 18.2 1.4e-08 34.9 0.2 10.9 9 2 2 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.1 KZN92449.1 - 4.4e-21 74.9 8.8 2e-07 31.1 0.1 8.5 6 2 4 10 10 10 5 HEAT repeats HEAT PF02985.17 KZN92449.1 - 5.4e-21 72.7 12.0 0.00038 20.2 0.0 12.1 13 0 0 13 13 12 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KZN92449.1 - 7.5e-10 39.0 0.2 0.0059 16.9 0.0 5.9 2 2 3 5 5 5 3 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KZN92449.1 - 3.2e-09 36.6 0.0 0.053 13.1 0.0 5.4 4 1 2 6 6 6 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KZN92449.1 - 1.4e-08 34.3 0.1 0.089 12.1 0.0 6.0 4 3 2 6 6 6 3 CLASP N terminal Adaptin_N PF01602.15 KZN92449.1 - 2.6e-07 29.3 0.0 0.0011 17.4 0.1 3.1 2 1 0 2 2 2 2 Adaptin N terminal region MMS19_C PF12460.3 KZN92449.1 - 3.9e-06 25.8 2.6 0.00031 19.5 0.8 4.0 3 2 1 4 4 4 1 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 KZN92449.1 - 4.7e-05 21.8 0.1 0.0031 15.8 0.0 2.6 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 KZN92449.1 - 9.7e-05 22.0 2.2 1.4 8.8 0.1 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KZN92449.1 - 0.00028 20.7 0.3 2.8 7.7 0.0 5.0 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.3 KZN92449.1 - 0.0018 18.2 0.1 11 5.9 0.0 4.9 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) DUF4042 PF13251.1 KZN92449.1 - 0.0019 17.6 1.8 11 5.3 0.0 5.0 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) IBN_N PF03810.14 KZN92449.1 - 0.0033 17.3 0.0 0.027 14.3 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain SEN1_N PF12726.2 KZN92449.1 - 0.028 12.4 1.3 0.067 11.2 0.1 2.3 2 0 0 2 2 2 0 SEN1 N terminal DNA_alkylation PF08713.6 KZN92449.1 - 0.043 13.3 0.0 0.16 11.4 0.0 2.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme NmrA PF05368.8 KZN92450.1 - 1.6e-25 89.7 0.0 2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN92450.1 - 5.5e-10 39.5 0.0 8.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KZN92450.1 - 2.6e-06 27.7 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KZN92450.1 - 0.00026 19.9 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KZN92450.1 - 0.0003 19.5 0.0 0.00047 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN92450.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KZN92450.1 - 0.0026 16.8 0.1 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 KZN92450.1 - 0.003 18.1 0.1 0.0055 17.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 KZN92450.1 - 0.0035 17.2 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN92450.1 - 0.0044 16.7 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KZN92450.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 KZN92450.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KZN92450.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein PrpR_N PF06506.6 KZN92450.1 - 0.12 11.7 0.3 0.34 10.3 0.2 1.7 1 1 0 1 1 1 0 Propionate catabolism activator Bac_rhamnosid PF05592.6 KZN92451.1 - 3.7e-32 111.2 3.9 4.9e-24 84.4 2.8 2.4 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 KZN92451.1 - 0.00045 19.0 0.1 0.00067 18.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 KZN92451.1 - 0.017 13.8 8.2 0.025 13.2 5.2 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF608 Fe-ADH PF00465.14 KZN92452.1 - 1.1e-67 228.2 0.0 1.4e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KZN92452.1 - 7.5e-11 41.8 0.0 6.4e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Chalcone PF02431.10 KZN92453.1 - 7.2e-66 221.3 0.0 9.1e-66 221.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 KZN92454.1 - 3.8e-20 71.6 0.1 6.6e-20 70.8 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.9 KZN92454.1 - 0.00059 20.0 0.1 0.00076 19.6 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 KZN92454.1 - 0.0055 16.8 0.1 0.0091 16.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 KZN92454.1 - 0.015 14.9 0.1 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KZN92454.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.1 KZN92454.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.15 KZN92454.1 - 0.021 14.4 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 KZN92454.1 - 0.029 14.3 0.0 0.058 13.4 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KZN92454.1 - 0.065 13.2 0.7 5.7 6.9 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin DUF244 PF03112.9 KZN92454.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF BAG PF02179.11 KZN92456.1 - 4.8e-12 45.8 0.0 8.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KZN92456.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YopE_N PF09020.5 KZN92456.1 - 0.62 10.1 9.9 1.8 8.5 2.1 2.3 2 0 0 2 2 2 0 YopE, N terminal DUF605 PF04652.11 KZN92456.1 - 9.1 5.5 12.0 13 5.0 8.3 1.2 1 0 0 1 1 1 0 Vta1 like LMBR1 PF04791.11 KZN92457.1 - 6.1e-30 104.2 1.9 8.7e-30 103.7 1.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.7 KZN92457.1 - 4.3e-05 22.1 1.4 4.3e-05 22.1 1.0 2.1 2 0 0 2 2 2 1 Fusaric acid resistance protein family NAD_binding_9 PF13454.1 KZN92457.1 - 0.046 13.4 0.1 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding IncA PF04156.9 KZN92457.1 - 0.054 13.0 0.2 0.054 13.0 0.1 2.5 2 1 0 2 2 2 0 IncA protein Syntaxin_2 PF14523.1 KZN92457.1 - 0.22 11.5 0.1 0.47 10.5 0.1 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Med15_fungi PF05397.7 KZN92458.1 - 2.1e-30 105.0 0.2 2.1e-30 105.0 0.1 5.4 8 0 0 8 8 8 1 Mediator complex subunit 15 Nuc_sug_transp PF04142.10 KZN92459.1 - 2e-09 36.9 0.9 3.4e-09 36.1 0.6 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KZN92459.1 - 4.1e-08 32.5 10.3 8.1e-08 31.5 7.1 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KZN92459.1 - 7.8e-08 32.4 23.1 3.7e-05 23.7 2.3 3.1 2 1 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KZN92459.1 - 0.00021 21.4 2.9 0.00021 21.4 2.0 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KZN92459.1 - 0.00044 19.9 20.9 0.0077 15.8 6.4 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family Lyase_aromatic PF00221.14 KZN92459.1 - 0.029 12.8 0.1 0.041 12.3 0.1 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase DUF460 PF04312.8 KZN92459.1 - 0.19 11.2 0.3 0.35 10.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF3353 PF11833.3 KZN92459.1 - 4.1 6.8 5.8 13 5.1 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Adaptin_N PF01602.15 KZN92460.1 - 1.2e-139 466.0 1.2 1.5e-139 465.7 0.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KZN92460.1 - 1.7e-16 60.5 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KZN92460.1 - 1.7e-07 31.3 1.5 0.014 15.6 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KZN92460.1 - 0.0027 17.5 5.3 0.014 15.2 0.6 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KZN92460.1 - 0.005 16.8 1.8 13 6.1 0.0 4.8 5 1 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 KZN92460.1 - 0.0086 15.6 0.3 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 KZN92460.1 - 0.013 15.3 0.2 72 3.4 0.1 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KZN92460.1 - 0.016 15.6 0.2 6.4 7.4 0.0 4.5 3 1 2 5 5 5 0 HEAT-like repeat MBOAT PF03062.14 KZN92461.1 - 3.5e-36 124.9 15.5 6.3e-36 124.1 10.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3671 PF12420.3 KZN92461.1 - 3.8 7.5 6.2 0.49 10.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function ALO PF04030.9 KZN92462.1 - 9.9e-09 35.1 0.4 1.3e-08 34.7 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DnaJ PF00226.26 KZN92463.1 - 1.1e-18 66.7 0.6 1.1e-18 66.7 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain Metallophos PF00149.23 KZN92464.1 - 0.0045 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L13 PF00572.13 KZN92465.1 - 5.7e-28 97.5 0.1 1.2e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 KZN92465.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MOSC_N PF03476.11 KZN92466.1 - 1.8e-12 47.0 0.0 3.6e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KZN92466.1 - 1.3e-10 40.8 0.2 8.9e-10 38.1 0.1 2.2 1 1 0 1 1 1 1 MOSC domain AMP-binding PF00501.23 KZN92467.1 - 9.6e-70 235.0 0.1 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN92467.1 - 5.3e-16 59.3 0.0 1.2e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 KZN92468.1 - 3.1e-11 42.8 0.0 1.1e-10 41.0 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KZN92468.1 - 2.3e-10 40.0 14.8 0.021 14.5 0.3 6.6 3 1 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 KZN92468.1 - 5e-08 32.3 11.1 0.24 11.0 0.0 7.4 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KZN92468.1 - 8.2e-07 28.4 16.2 4.9 7.5 0.0 10.9 13 0 0 13 13 13 1 Leucine Rich repeat LRR_1 PF00560.28 KZN92468.1 - 0.0022 17.7 19.9 76 3.9 0.0 10.1 8 3 0 8 8 8 0 Leucine Rich Repeat F-box PF00646.28 KZN92468.1 - 0.0033 17.0 0.0 0.02 14.5 0.0 2.5 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.6 KZN92468.1 - 0.078 12.5 1.5 0.7 9.4 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) Recep_L_domain PF01030.19 KZN92468.1 - 0.089 12.7 0.5 1e+02 2.9 0.0 4.0 2 2 2 5 5 5 0 Receptor L domain Sugar_tr PF00083.19 KZN92469.1 - 1.9e-100 336.5 34.5 2.2e-100 336.3 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92469.1 - 1.1e-27 96.6 18.6 1.1e-27 96.6 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 KZN92470.1 - 1.8e-33 116.2 4.1 1e-30 107.2 2.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KZN92470.1 - 2.4e-19 69.5 0.2 4.6e-18 65.3 0.3 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Oxidored_molyb PF00174.14 KZN92471.1 - 5.4e-40 136.5 0.0 8.1e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KZN92471.1 - 1.5e-08 34.3 0.7 2.5e-08 33.6 0.5 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FMN_bind_2 PF04299.7 KZN92472.1 - 8.1e-58 194.6 0.1 9.6e-58 194.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain GATase PF00117.23 KZN92473.1 - 3.2e-10 39.7 0.0 4.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Aldedh PF00171.17 KZN92475.1 - 8.9e-145 482.5 0.6 1e-144 482.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF126 PF01989.11 KZN92475.1 - 0.13 11.9 1.8 7.1 6.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF126 Sugar_tr PF00083.19 KZN92476.1 - 5.4e-98 328.5 25.5 6.2e-98 328.3 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92476.1 - 6.2e-19 67.9 25.1 6.2e-19 67.9 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN92477.1 - 3e-19 68.9 0.1 4.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92477.1 - 3e-06 27.0 15.4 7.6e-06 25.7 10.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAXi_N PF14543.1 KZN92477.1 - 0.036 14.0 1.9 0.11 12.4 1.3 1.8 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Transketolase_N PF00456.16 KZN92478.1 - 1.3e-105 352.9 0.0 1.7e-105 352.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KZN92478.1 - 1.1e-33 116.2 0.0 2.6e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KZN92478.1 - 8.1e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KZN92478.1 - 9.4e-08 31.3 0.0 6.3e-07 28.6 0.0 2.3 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KZN92478.1 - 0.00028 20.4 0.2 0.00096 18.7 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KZN92478.1 - 0.0028 16.4 0.1 0.0057 15.4 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.7 KZN92479.1 - 2.2e-25 88.5 0.6 5e-25 87.3 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN92479.1 - 2.6e-15 56.1 0.3 2.6e-15 56.1 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase MCE PF02470.15 KZN92479.1 - 0.039 13.9 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 mce related protein HupF_HypC PF01455.13 KZN92479.1 - 0.078 12.9 0.3 3 7.8 0.0 2.5 2 0 0 2 2 2 0 HupF/HypC family Pyr_redox_3 PF13738.1 KZN92480.1 - 1.3e-23 84.1 0.0 2.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN92480.1 - 9.9e-14 50.4 0.1 5.3e-13 48.0 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN92480.1 - 1.1e-11 44.5 0.0 3e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN92480.1 - 1.2e-07 31.8 0.0 2e-06 27.8 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN92480.1 - 2.2e-06 26.8 0.2 0.00025 20.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KZN92480.1 - 0.0025 16.7 0.0 0.86 8.4 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN92480.1 - 0.0026 17.5 0.0 0.075 12.7 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KZN92480.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KZN92480.1 - 0.19 11.8 0.1 29 4.7 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KZN92481.1 - 5.4e-24 85.0 0.2 9.6e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN92481.1 - 2.2e-06 27.4 0.1 4.3e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 KZN92481.1 - 0.0011 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF987 PF06174.6 KZN92481.1 - 0.12 11.8 0.1 5.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF987) adh_short_C2 PF13561.1 KZN92482.1 - 8.3e-31 107.5 0.0 9.9e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN92482.1 - 4.9e-23 81.8 0.0 6.3e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN92482.1 - 3.9e-12 46.1 0.0 6.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN92482.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Thiol_cytolysin PF01289.14 KZN92483.1 - 0.0036 15.7 0.0 0.0053 15.1 0.0 1.2 1 0 0 1 1 1 1 Thiol-activated cytolysin Arylsulfotran_2 PF14269.1 KZN92485.1 - 3.4e-18 65.8 0.0 4.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN92485.1 - 0.12 10.8 0.0 0.95 7.8 0.0 2.1 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) NYN PF01936.13 KZN92486.1 - 2.9e-32 111.9 0.0 4.4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 KZN92486.1 - 2.2e-21 75.4 0.1 4e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DUF1793 PF08760.6 KZN92487.1 - 2e-24 86.3 0.7 2.9e-24 85.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) MFS_1 PF07690.11 KZN92488.1 - 8.5e-34 116.8 59.6 1.4e-32 112.7 41.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN92488.1 - 1.1e-10 40.3 15.1 2.3e-10 39.2 10.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN92488.1 - 3.1e-10 39.2 40.0 4.8e-10 38.5 7.2 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter PsbH PF00737.15 KZN92488.1 - 5.3 6.7 9.6 0.58 9.7 0.3 3.4 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein Peptidase_M28 PF04389.12 KZN92489.1 - 1e-29 103.5 0.0 1.6e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.15 KZN92489.1 - 0.0023 18.1 1.4 0.0023 18.1 1.0 5.6 6 0 0 6 6 6 1 ATP synthase protein 8 Peptidase_M20 PF01546.23 KZN92489.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Epimerase PF01370.16 KZN92491.1 - 1.2e-26 93.6 0.0 2.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN92491.1 - 2.7e-12 47.0 0.0 2.5e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN92491.1 - 1.2e-10 40.7 0.0 5.9e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KZN92491.1 - 4.2e-08 32.4 0.0 7.2e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KZN92491.1 - 1.9e-07 30.0 0.1 7.6e-07 28.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN92491.1 - 0.0031 17.4 0.1 0.014 15.3 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN92491.1 - 0.011 14.6 0.0 0.053 12.4 0.0 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 KZN92491.1 - 0.02 14.5 0.2 0.094 12.3 0.1 2.1 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 KZN92491.1 - 0.06 12.5 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Lipase_GDSL_2 PF13472.1 KZN92492.1 - 1e-19 71.3 0.1 1.2e-19 71.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN92492.1 - 6.6e-07 29.3 0.0 8.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KZN92492.1 - 1.8e-05 24.5 0.0 0.027 14.2 0.0 2.8 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Pro_racemase PF05544.6 KZN92494.1 - 1.2e-125 418.6 0.1 1.4e-125 418.4 0.1 1.0 1 0 0 1 1 1 1 Proline racemase CorA PF01544.13 KZN92495.1 - 4.5e-05 22.6 2.3 9.7e-05 21.5 1.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.1 KZN92496.1 - 5e-45 153.8 52.1 6.3e-45 153.4 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN92496.1 - 5.9e-29 100.7 47.4 6.8e-29 100.5 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KZN92497.1 - 3.2e-27 95.1 3.8 4.5e-27 94.6 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 KZN92498.1 - 1.5e-59 201.1 0.0 2e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 KZN92499.1 - 2.1e-28 99.0 16.9 2.1e-28 99.0 11.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.15 KZN92499.1 - 0.016 14.5 1.2 4.4 6.5 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF21 DUF4231 PF14015.1 KZN92499.1 - 0.074 13.0 0.0 0.074 13.0 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Fungal_trans PF04082.13 KZN92500.1 - 1.1e-19 70.3 0.1 2e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3535 PF12054.3 KZN92502.1 - 7.5e-152 505.9 0.0 2.1e-151 504.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KZN92502.1 - 2.5e-70 236.6 0.0 4.2e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KZN92502.1 - 3.9e-16 57.6 12.4 0.2 11.8 0.0 10.1 10 0 0 10 10 10 6 HEAT repeat Helicase_C PF00271.26 KZN92502.1 - 2.3e-14 52.9 0.0 6.8e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KZN92502.1 - 4.5e-07 30.1 0.0 0.092 13.1 0.0 3.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 KZN92502.1 - 1.8e-05 24.9 16.0 0.072 13.3 0.1 7.5 7 1 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 KZN92502.1 - 0.0017 18.8 17.5 3.8 8.1 0.0 8.8 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 KZN92502.1 - 0.017 14.4 0.1 7.3 5.8 0.0 3.9 4 1 2 6 6 6 0 CLASP N terminal Cnd1 PF12717.2 KZN92502.1 - 0.081 12.7 1.2 6.7 6.5 0.0 4.0 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ndufs5 PF10200.4 KZN92503.1 - 0.00078 19.3 0.0 0.00098 19.0 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KZN92503.1 - 0.005 16.9 0.3 0.007 16.4 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 KZN92503.1 - 0.0055 16.7 0.2 0.0077 16.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KZN92503.1 - 0.0089 15.9 0.1 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 CHCH domain Sec39 PF08314.6 KZN92504.1 - 7.5e-249 827.4 4.8 8.5e-249 827.2 3.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.20 KZN92505.1 - 2.2e-61 207.3 0.0 2.6e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92505.1 - 3.4e-36 124.6 0.0 4.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92505.1 - 1.5e-09 37.2 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN92505.1 - 0.14 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.1 KZN92507.1 - 4.8e-45 151.0 26.8 9.7e-18 63.5 1.6 5.6 3 2 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 KZN92507.1 - 1.9e-34 114.8 11.6 1.3e-05 24.6 0.2 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 KZN92507.1 - 1.9e-34 115.8 13.7 6.1e-08 31.9 0.3 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 KZN92507.1 - 7.2e-27 92.9 1.7 7.2e-27 92.9 1.2 2.4 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 KZN92507.1 - 7.4e-26 90.2 10.4 1.4e-06 28.8 0.1 5.9 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92507.1 - 3.5e-22 78.4 15.7 7.7e-06 26.1 0.0 5.7 4 2 1 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 KZN92507.1 - 8.5e-19 67.4 3.9 3.1e-08 33.6 0.0 4.0 2 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KZN92507.1 - 7e-18 63.5 11.6 0.1 13.2 0.1 8.2 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KZN92507.1 - 1.7e-16 59.9 11.8 9e-06 25.5 0.7 6.1 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92507.1 - 3e-16 58.1 12.3 0.0019 18.2 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92507.1 - 7.6e-14 50.3 3.4 0.53 10.2 0.1 7.2 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92507.1 - 3.6e-13 48.2 14.2 0.0028 17.3 0.3 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KZN92507.1 - 2.6e-11 43.2 8.7 0.27 11.7 0.4 7.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KZN92507.1 - 7.7e-11 41.6 5.8 0.00046 19.9 0.1 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 KZN92507.1 - 2.5e-07 30.0 8.5 0.018 14.1 0.1 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KZN92507.1 - 3.7e-07 29.9 11.2 0.0057 16.5 0.2 5.4 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 KZN92507.1 - 0.00055 19.6 0.1 0.12 12.1 0.0 4.2 3 1 2 5 5 4 1 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 KZN92507.1 - 0.0013 18.9 3.3 5.3 7.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF928 PF06051.7 KZN92507.1 - 0.0026 17.3 0.4 0.32 10.5 0.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF928) Alkyl_sulf_dimr PF14863.1 KZN92507.1 - 0.0033 17.6 5.0 1.3 9.2 0.3 4.3 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KZN92507.1 - 0.028 14.5 14.9 0.32 11.1 0.0 5.3 5 2 1 6 6 5 0 Tetratricopeptide repeat PPR PF01535.15 KZN92507.1 - 0.041 13.8 1.5 21 5.3 0.0 4.0 5 0 0 5 5 2 0 PPR repeat SPO22 PF08631.5 KZN92507.1 - 0.042 12.9 1.6 0.083 11.9 0.3 2.1 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.12 KZN92507.1 - 0.082 13.2 1.8 3.6 7.8 0.2 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.4 KZN92507.1 - 0.097 11.9 1.7 11 5.3 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR HEAT_2 PF13646.1 KZN92507.1 - 0.1 12.8 3.4 0.31 11.3 0.3 2.6 2 0 0 2 2 2 0 HEAT repeats MIT PF04212.13 KZN92507.1 - 0.12 12.3 7.8 7.7 6.4 0.1 4.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 KZN92509.1 - 2.5e-39 134.9 0.0 3.8e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92509.1 - 3.1e-30 105.1 0.0 4.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN92509.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN92509.1 - 0.018 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN92509.1 - 0.034 13.8 0.0 5.2 6.7 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Med10 PF09748.4 KZN92510.1 - 6.1e-44 148.9 0.0 7.3e-44 148.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 KZN92510.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Fungal_trans PF04082.13 KZN92511.1 - 2e-25 89.1 2.1 3.8e-25 88.2 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA_lig_kinase PF08303.6 KZN92511.1 - 0.18 11.7 0.3 0.73 9.6 0.2 1.9 1 1 0 1 1 1 0 tRNA ligase kinase domain HpcH_HpaI PF03328.9 KZN92512.1 - 1.2e-37 128.9 0.0 1.4e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 KZN92512.1 - 0.12 11.5 0.0 5.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase ILVD_EDD PF00920.16 KZN92513.1 - 6.5e-154 513.1 0.0 7.5e-154 512.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Erythro_esteras PF05139.9 KZN92514.1 - 2.4e-142 474.2 2.1 2.7e-142 474.0 1.5 1.0 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.4 KZN92516.1 - 4.4e-67 225.5 2.4 5.7e-67 225.2 1.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Mito_carr PF00153.22 KZN92517.1 - 1.3e-38 130.5 0.8 1.6e-20 72.6 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein GTP_EFTU PF00009.22 KZN92518.1 - 4.4e-35 120.8 2.1 2.3e-34 118.5 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KZN92518.1 - 3.4e-26 91.2 1.8 1.2e-25 89.4 0.7 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 IF2_N PF04760.10 KZN92518.1 - 9.1e-09 34.8 0.0 2.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.20 KZN92518.1 - 1.1e-08 35.0 1.1 2.5e-06 27.4 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN92518.1 - 2.9e-07 30.4 0.0 8.2e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KZN92518.1 - 0.00064 20.1 0.1 0.0015 19.0 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KZN92518.1 - 0.0059 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KZN92518.1 - 0.013 14.9 0.1 0.039 13.4 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3279 PF11682.3 KZN92518.1 - 0.041 13.4 0.6 0.085 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) zf-RanBP PF00641.13 KZN92518.1 - 0.052 12.6 4.6 0.11 11.6 3.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others FeoB_N PF02421.13 KZN92518.1 - 0.088 12.0 0.1 0.25 10.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DZR PF12773.2 KZN92518.1 - 0.2 11.5 1.4 0.44 10.4 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 KZN92518.1 - 0.35 10.5 3.1 0.72 9.5 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 KZN92518.1 - 0.58 9.8 6.4 1.2 8.8 4.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Zn_clus PF00172.13 KZN92519.1 - 1.6e-08 34.2 9.4 1.6e-08 34.2 6.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92519.1 - 6.9e-05 21.8 0.0 0.00031 19.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain EI24 PF07264.6 KZN92520.1 - 5.9e-06 25.8 16.7 1e-05 25.0 11.6 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4231 PF14015.1 KZN92520.1 - 1.3 8.9 6.0 0.93 9.4 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HAD_2 PF13419.1 KZN92521.1 - 3.7e-13 50.0 0.0 4.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN92521.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HNH PF01844.18 KZN92522.1 - 0.021 14.6 0.6 0.042 13.7 0.4 1.5 1 1 0 1 1 1 0 HNH endonuclease Trypan_PARP PF05887.6 KZN92523.1 - 1.8 8.3 72.6 0.47 10.2 24.2 2.8 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Ceramidase_alk PF04734.8 KZN92524.1 - 1.4e-274 912.1 0.0 1.7e-274 911.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 KZN92525.1 - 7.1e-55 185.8 5.9 7.7e-55 185.7 4.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) 3Beta_HSD PF01073.14 KZN92526.1 - 8.9e-27 93.5 0.0 2.8e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN92526.1 - 2.2e-12 46.9 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN92526.1 - 8e-10 38.0 0.0 5.9e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KZN92526.1 - 2.4e-08 34.2 0.0 1.9e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN92526.1 - 8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KZN92526.1 - 0.00088 18.2 0.0 0.032 13.1 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 KZN92526.1 - 0.31 10.9 1.9 5.9 6.7 1.3 2.6 1 1 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 KZN92527.1 - 4.1e-41 140.8 31.7 4.1e-41 140.8 21.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN92527.1 - 3.3e-14 52.3 15.1 3.3e-14 52.3 10.5 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KZN92527.1 - 1.7e-08 33.1 6.7 3e-08 32.3 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KZN92527.1 - 0.12 10.5 9.9 0.011 13.9 3.5 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Corona_S2 PF01601.11 KZN92527.1 - 0.29 9.2 0.6 0.47 8.4 0.4 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ten1 PF12658.2 KZN92528.1 - 9.5e-47 157.8 0.0 1.1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KZN92528.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Snf7 PF03357.16 KZN92529.1 - 3.5e-35 120.8 17.8 3.5e-35 120.8 12.3 2.0 1 1 1 2 2 2 1 Snf7 Fmp27_WPPW PF10359.4 KZN92529.1 - 0.11 10.8 8.6 0.15 10.4 6.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IFT57 PF10498.4 KZN92529.1 - 0.92 8.1 13.4 1.4 7.5 8.9 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TMCO5 PF14992.1 KZN92529.1 - 2 7.4 17.0 1.1 8.3 10.4 1.5 1 1 1 2 2 2 0 TMCO5 family DUF3573 PF12097.3 KZN92529.1 - 3.1 6.3 8.1 5.6 5.4 5.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Atg14 PF10186.4 KZN92529.1 - 3.1 6.6 13.9 5.1 5.9 9.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3138 PF11336.3 KZN92529.1 - 6.7 4.7 7.5 11 4.0 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) NuA4 PF09340.5 KZN92529.1 - 7.6 6.2 7.8 0.45 10.1 0.3 2.6 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 CRC_subunit PF08624.5 KZN92530.1 - 2e-56 189.7 0.0 2.9e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 KZN92531.1 - 1e-70 237.9 0.0 1.4e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92531.1 - 9.8e-31 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KZN92531.1 - 3.4e-15 56.2 0.8 2.6e-14 53.4 0.6 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KZN92531.1 - 5.7e-09 35.3 0.1 1.6e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KZN92531.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KZN92531.1 - 0.057 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KZN92531.1 - 0.07 12.6 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.2 KZN92532.1 - 2e-20 72.9 0.0 7.3e-09 35.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KZN92532.1 - 3.2e-18 64.5 0.1 2.5e-06 27.0 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KZN92532.1 - 4.6e-14 51.1 0.3 0.00017 21.5 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 KZN92532.1 - 5.6e-12 45.8 1.0 0.0041 17.5 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN92532.1 - 1.3e-11 44.2 0.2 0.00015 21.8 0.0 4.4 3 3 1 4 4 4 2 Ankyrin repeats (many copies) FadR_C PF07840.7 KZN92532.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 FadR C-terminal domain F-box PF00646.28 KZN92534.1 - 0.0031 17.1 0.0 0.0088 15.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KZN92534.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like tRNA-synt_1c PF00749.16 KZN92535.1 - 2.4e-99 331.9 0.0 3.2e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KZN92535.1 - 1.7e-31 109.2 0.0 5.4e-31 107.5 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.12 KZN92535.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain AAA PF00004.24 KZN92536.1 - 1.2e-40 138.7 0.0 2.4e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KZN92536.1 - 3.4e-05 23.0 0.1 0.00011 21.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN92536.1 - 6.3e-05 22.7 0.0 0.00031 20.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN92536.1 - 0.00035 20.5 0.2 0.017 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KZN92536.1 - 0.0012 18.9 0.2 0.031 14.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KZN92536.1 - 0.0028 16.6 0.0 0.0074 15.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 KZN92536.1 - 0.0045 16.2 0.2 0.05 12.8 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.9 KZN92536.1 - 0.0056 16.6 3.4 0.0096 15.8 0.0 3.0 3 2 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KZN92536.1 - 0.0062 15.7 0.1 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KZN92536.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KZN92536.1 - 0.012 15.2 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KZN92536.1 - 0.024 14.0 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KZN92536.1 - 0.036 13.4 0.9 0.49 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KZN92536.1 - 0.038 13.5 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KZN92536.1 - 0.041 13.7 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KZN92536.1 - 0.043 12.8 0.9 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KZN92536.1 - 0.047 14.5 0.1 0.047 14.5 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KZN92536.1 - 0.56 9.7 4.6 0.79 9.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain TauD PF02668.11 KZN92537.1 - 3.1e-38 131.9 0.8 4.8e-38 131.3 0.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KZN92537.1 - 2.1e-08 34.4 0.0 6.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 KZN92537.1 - 0.00028 21.3 0.2 0.023 15.1 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 KZN92537.1 - 0.023 13.6 0.1 0.055 12.3 0.1 1.6 1 1 0 1 1 1 0 CsiD MaoC_dehydratas PF01575.14 KZN92538.1 - 2.6e-23 81.7 0.0 4.7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KZN92538.1 - 1.1e-07 31.6 0.0 3.4e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Per1 PF04080.8 KZN92539.1 - 4e-108 360.8 11.9 5e-108 360.5 8.2 1.1 1 0 0 1 1 1 1 Per1-like PGM_PMM_II PF02879.11 KZN92540.1 - 6.1e-16 58.6 0.7 4.9e-15 55.7 0.1 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KZN92540.1 - 6.2e-11 42.1 0.2 1.7e-10 40.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.11 KZN92540.1 - 4.6e-06 26.1 0.2 1.5e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KZN92540.1 - 0.00034 20.6 0.2 0.0014 18.6 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.24 KZN92541.1 - 5.9e-45 152.7 0.0 8.7e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN92541.1 - 3.8e-25 87.5 0.0 8.7e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN92541.1 - 0.03 14.1 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Brix PF04427.13 KZN92542.1 - 9.7e-58 194.9 0.5 1.3e-57 194.5 0.3 1.2 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.12 KZN92543.1 - 5.9e-35 119.0 0.1 1e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.12 KZN92544.1 - 1e-59 201.0 0.1 1.5e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III GxDLY PF14607.1 KZN92544.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type 2OG-FeII_Oxy PF03171.15 KZN92545.1 - 9e-05 22.7 0.0 0.00031 20.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KZN92545.1 - 0.00037 20.9 0.5 0.0011 19.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 KZN92546.1 - 2.4e-27 95.9 1.6 3.5e-27 95.3 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN92546.1 - 1.5e-11 44.2 0.3 2.6e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN92546.1 - 2.1e-09 37.5 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.27 KZN92547.1 - 4.2e-39 131.0 2.0 5.3e-09 35.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 KZN92547.1 - 1.1e-29 102.2 13.0 2.5e-29 101.1 9.0 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KZN92547.1 - 0.00039 20.1 0.4 0.0017 18.1 0.0 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KZN92547.1 - 0.05 11.7 5.6 0.099 10.7 0.1 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PCI PF01399.22 KZN92548.1 - 1.5e-20 73.4 1.4 3.6e-20 72.2 0.1 2.3 2 1 0 2 2 2 1 PCI domain TPR_8 PF13181.1 KZN92548.1 - 3.3e-05 23.3 6.8 9.3 6.2 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat DDRGK PF09756.4 KZN92548.1 - 6.5e-05 22.4 0.5 0.00011 21.6 0.3 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.1 KZN92548.1 - 0.00044 20.1 17.4 0.6 10.0 2.8 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92548.1 - 0.0015 18.9 9.5 29 5.6 0.6 6.2 4 2 2 6 6 6 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.1 KZN92548.1 - 0.0023 17.6 0.2 1.1 9.1 0.1 3.3 3 1 1 4 4 4 1 Crp-like helix-turn-helix domain PCI_Csn8 PF10075.4 KZN92548.1 - 0.013 15.3 0.4 0.032 14.0 0.3 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Soyouz_module PF14313.1 KZN92548.1 - 0.05 13.1 0.2 0.32 10.5 0.0 2.4 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Prefoldin_2 PF01920.15 KZN92548.1 - 0.059 13.1 3.0 0.087 12.5 0.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit TPR_2 PF07719.12 KZN92548.1 - 0.11 12.4 9.5 7.2 6.7 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92548.1 - 0.21 11.4 9.2 1.4 8.9 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN92548.1 - 0.57 10.7 5.1 45 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KZN92548.1 - 1.7 9.4 14.1 6 7.6 1.4 4.6 5 2 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KZN92548.1 - 6.3 6.5 10.1 12 5.6 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat SWIB PF02201.13 KZN92549.1 - 8.1e-16 57.4 0.0 1.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.11 KZN92550.1 - 3.6e-52 176.8 15.4 6.2e-52 176.0 10.7 1.4 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.20 KZN92551.1 - 4.9e-13 48.8 0.0 1.3e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92551.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SAP30_Sin3_bdg PF13867.1 KZN92552.1 - 4.2e-06 26.5 0.2 1.6 8.6 0.0 6.9 8 1 1 9 9 9 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2730 PF10805.3 KZN92552.1 - 1.8 8.3 10.9 0.18 11.5 0.4 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) DUF3647 PF12363.3 KZN92552.1 - 2.5 8.2 21.0 13 5.9 0.0 8.7 7 2 1 8 8 8 0 Phage protein PMC2NT PF08066.7 KZN92552.1 - 2.7 8.3 23.9 3.1 8.1 0.0 7.6 5 1 0 5 5 5 0 PMC2NT (NUC016) domain Ribosomal_L27e PF01777.13 KZN92553.1 - 1.4e-36 124.5 1.1 1.8e-36 124.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KZN92553.1 - 0.0072 16.0 2.1 0.0094 15.6 0.5 1.9 2 0 0 2 2 2 1 KOW motif TCL1_MTCP1 PF01840.12 KZN92554.1 - 0.071 12.6 0.6 0.24 10.9 0.4 1.9 1 1 0 1 1 1 0 TCL1/MTCP1 family MAGE PF01454.14 KZN92556.1 - 5.3e-42 143.3 0.0 6.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 MAGE family PBP1_TM PF14812.1 KZN92556.1 - 3.3 8.0 14.2 3.2 8.1 0.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GTP_EFTU PF00009.22 KZN92557.1 - 4.4e-57 192.5 0.0 6.5e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KZN92557.1 - 6e-37 125.7 0.1 2.3e-36 123.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KZN92557.1 - 1.1e-14 54.2 0.7 3.2e-14 52.7 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KZN92557.1 - 0.00013 21.5 0.2 0.00029 20.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KZN92557.1 - 0.0015 18.4 0.3 0.005 16.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 KZN92557.1 - 0.025 14.4 0.2 0.27 11.0 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain TFIIS_C PF01096.13 KZN92558.1 - 3.3e-20 71.4 2.3 3.3e-20 71.4 1.6 2.9 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KZN92558.1 - 1.9e-07 30.6 4.8 4.7e-07 29.3 0.9 2.7 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KZN92558.1 - 0.0034 17.1 4.0 0.33 10.8 0.2 2.6 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 KZN92558.1 - 0.0064 16.7 0.2 0.53 10.5 0.0 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Elf1 PF05129.8 KZN92558.1 - 0.011 15.4 3.1 0.7 9.6 0.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 KZN92558.1 - 0.026 13.7 11.1 0.16 11.2 2.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KZN92558.1 - 0.033 14.0 7.6 0.86 9.5 0.2 2.9 2 1 0 2 2 2 0 IBR domain zinc_ribbon_4 PF13717.1 KZN92558.1 - 0.04 13.6 6.7 1.9 8.2 0.1 3.1 3 1 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KZN92558.1 - 0.052 13.3 1.3 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-TFIIB PF13453.1 KZN92558.1 - 0.11 11.7 4.7 0.23 10.6 0.4 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_5 PF13719.1 KZN92558.1 - 0.21 11.2 8.1 1.7 8.2 0.1 3.1 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KZN92558.1 - 0.29 10.9 7.4 0.28 11.0 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 KZN92558.1 - 0.9 9.9 6.4 8.5 6.8 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.7 KZN92558.1 - 0.96 8.8 6.2 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1 PF03811.8 KZN92558.1 - 1.3 8.5 8.6 0.17 11.4 0.9 2.9 3 1 0 3 3 3 0 InsA N-terminal domain zinc_ribbon_2 PF13240.1 KZN92558.1 - 6.5 6.3 9.9 5.8 6.5 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin PF00301.15 KZN92558.1 - 8.7 6.3 6.9 16 5.4 0.1 3.5 4 0 0 4 4 4 0 Rubredoxin Nudix_N_2 PF14803.1 KZN92558.1 - 9.1 6.0 7.2 31 4.3 1.9 3.1 2 1 0 2 2 2 0 Nudix N-terminal Ank_2 PF12796.2 KZN92559.1 - 5e-18 65.2 0.2 2.5e-09 37.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN92559.1 - 2.7e-09 36.3 0.1 0.0021 18.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KZN92559.1 - 5.2e-09 35.4 0.1 9.3e-05 22.0 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN92559.1 - 7.2e-08 32.4 0.1 0.0032 17.6 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN92559.1 - 2.7e-05 24.5 0.7 0.0025 18.2 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PPR_3 PF13812.1 KZN92559.1 - 0.0069 16.5 0.2 2.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 KZN92559.1 - 0.34 10.9 1.8 39 4.5 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Glycos_transf_1 PF00534.15 KZN92560.1 - 2.6e-19 69.2 0.0 4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KZN92560.1 - 3.4e-09 36.9 0.0 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KZN92560.1 - 0.00021 21.0 0.2 0.0012 18.5 0.0 2.4 4 0 0 4 4 4 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KZN92560.1 - 0.0041 17.3 0.1 0.0087 16.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KZN92560.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.3 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain 60KD_IMP PF02096.15 KZN92561.1 - 3.5e-13 49.6 0.7 4.7e-13 49.2 0.5 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.16 KZN92562.1 - 4.6e-42 144.1 0.0 9.3e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KZN92562.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KZN92562.1 - 0.0043 16.7 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 KZN92563.1 - 1.1e-90 304.1 0.1 1.9e-90 303.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Metallophos_2 PF12850.2 KZN92564.1 - 2.9e-12 46.6 0.1 4.7e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KZN92564.1 - 2.4e-09 36.9 1.1 9.2e-08 31.7 0.7 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HNH_2 PF13391.1 KZN92565.1 - 8.1e-13 47.9 0.0 2.1e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease PQ-loop PF04193.9 KZN92566.1 - 3.8e-21 74.3 0.2 3.8e-21 74.3 0.1 1.5 2 0 0 2 2 2 1 PQ loop repeat DUF4190 PF13828.1 KZN92566.1 - 0.13 11.8 2.4 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Ribosomal_60s PF00428.14 KZN92567.1 - 1.9e-24 85.8 10.7 2.3e-24 85.5 7.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 KZN92568.1 - 1e-53 180.9 6.8 4.4e-34 117.4 0.9 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Spc7 PF08317.6 KZN92568.1 - 0.0016 17.1 0.9 0.0042 15.8 0.6 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.7 KZN92568.1 - 0.002 16.3 2.2 0.059 11.5 0.1 2.4 2 1 0 2 2 2 1 Septation ring formation regulator, EzrA DUF2383 PF09537.5 KZN92568.1 - 0.022 14.9 0.1 0.088 13.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) PTRF_SDPR PF15237.1 KZN92568.1 - 0.064 12.6 0.9 0.16 11.3 0.6 1.6 1 0 0 1 1 1 0 PTRF/SDPR family DUF1664 PF07889.7 KZN92568.1 - 0.073 12.8 0.3 2.4 7.9 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1128 PF06569.6 KZN92568.1 - 0.12 12.0 0.5 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) HR1 PF02185.11 KZN92568.1 - 0.28 10.9 5.7 0.79 9.5 0.1 3.4 3 0 0 3 3 3 0 Hr1 repeat Snapin_Pallidin PF14712.1 KZN92568.1 - 0.39 11.0 6.2 0.48 10.7 0.4 3.7 4 0 0 4 4 4 0 Snapin/Pallidin Prefoldin_2 PF01920.15 KZN92568.1 - 0.46 10.2 7.0 5.9 6.6 0.1 3.7 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 KZN92568.1 - 0.47 10.2 2.5 0.69 9.7 0.7 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KZN92568.1 - 5.4 6.5 10.5 40 3.7 7.3 2.5 1 1 0 1 1 1 0 IncA protein Aconitase PF00330.15 KZN92570.1 - 3e-155 517.2 0.0 1.4e-154 515.0 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN92570.1 - 1e-38 132.4 0.0 1.6e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-H2C2_2 PF13465.1 KZN92571.1 - 1.1e-13 50.7 8.3 5.4e-08 32.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KZN92571.1 - 7.4e-12 44.8 12.3 8.3e-06 25.8 1.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN92571.1 - 1.1e-10 41.0 12.8 4e-05 23.6 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN92571.1 - 2.6e-07 30.5 1.8 0.031 14.4 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN92571.1 - 3.7e-05 23.7 1.2 0.014 15.5 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF4415 PF14384.1 KZN92571.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) zf-Di19 PF05605.7 KZN92571.1 - 0.1 12.7 1.7 0.22 11.6 1.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KZN92571.1 - 0.67 9.9 7.9 11 6.0 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 KZN92571.1 - 0.96 9.5 2.8 8.4 6.5 2.1 2.2 1 1 1 2 2 2 0 LIM domain Glyco_hydro_53 PF07745.8 KZN92572.1 - 3.5e-108 361.3 0.1 4e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.3 KZN92572.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Pkinase PF00069.20 KZN92573.1 - 3.6e-53 180.3 0.2 1.2e-36 126.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92573.1 - 3.5e-27 95.1 0.0 6.2e-26 91.0 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92573.1 - 9e-05 21.5 0.0 0.00025 20.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KZN92573.1 - 0.0021 17.8 1.5 0.03 14.0 1.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Myb_DNA-binding PF00249.26 KZN92574.1 - 3.3e-24 84.6 2.0 6.6e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KZN92574.1 - 7.2e-19 67.6 6.7 3.6e-14 52.6 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.3 KZN92574.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 KZN92574.1 - 0.027 14.5 1.4 0.093 12.8 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_38 PF13936.1 KZN92574.1 - 0.03 13.8 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 KZN92574.1 - 0.052 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_transf_41 PF13844.1 KZN92575.1 - 2.4e-99 332.4 0.0 9e-51 172.2 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.1 KZN92575.1 - 2.6e-20 71.8 10.2 1.9e-06 27.4 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KZN92575.1 - 2.1e-17 61.9 3.4 4.4e-05 22.9 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KZN92575.1 - 3.2e-15 54.7 8.6 0.03 14.2 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KZN92575.1 - 1.6e-12 47.1 8.1 1.1e-06 28.4 0.2 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92575.1 - 1.4e-10 40.8 6.1 0.067 13.8 0.0 5.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92575.1 - 2e-10 39.9 2.0 0.47 10.7 0.0 5.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN92575.1 - 4e-10 38.7 0.3 0.0014 18.2 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN92575.1 - 2e-07 31.5 10.1 0.11 13.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92575.1 - 4.9e-06 25.9 1.9 0.67 9.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92575.1 - 7.7e-06 26.1 5.2 0.029 14.7 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KZN92575.1 - 0.00027 20.7 12.4 0.17 11.8 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN92575.1 - 0.0021 18.1 0.6 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KZN92575.1 - 0.0061 16.9 2.2 12 6.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KZN92575.1 - 0.024 14.4 5.6 0.078 12.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 KZN92575.1 - 0.036 14.0 0.9 0.46 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetratrico peptide repeat DUF2225 PF09986.4 KZN92575.1 - 0.28 10.6 0.0 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Ribosomal_L11_N PF03946.9 KZN92576.1 - 1.6e-17 62.7 0.0 2.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KZN92576.1 - 2.5e-10 40.3 0.3 3.7e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 KZN92577.1 - 1.2e-81 273.7 0.0 1.7e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KZN92577.1 - 1.6e-33 114.1 0.0 3.1e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KZN92577.1 - 1.3e-29 102.5 0.0 2.7e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KZN92577.1 - 9.4e-17 60.2 3.7 2.1e-16 59.1 2.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KZN92577.1 - 6.1e-11 41.8 0.0 1.5e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DNA_primase_lrg PF04104.9 KZN92578.1 - 5.3e-87 291.3 0.0 7.4e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.17 KZN92579.1 - 2.6e-35 121.5 0.0 1.9e-20 73.2 0.0 2.1 1 1 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KZN92579.1 - 1.1e-14 53.8 0.0 1.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KZN92579.1 - 1.8e-05 25.0 0.0 0.00012 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN92579.1 - 0.00038 21.2 0.0 0.001 19.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KZN92579.1 - 0.00041 20.2 0.1 0.0053 16.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KZN92579.1 - 0.016 14.2 0.0 0.067 12.2 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KZN92579.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KZN92579.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 KZN92579.1 - 0.074 12.4 0.1 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase KTI12 PF08433.5 KZN92579.1 - 0.14 11.3 0.0 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SNase PF00565.12 KZN92580.1 - 2e-21 76.2 0.0 2.7e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue F-box-like PF12937.2 KZN92581.1 - 2.1e-08 33.7 0.2 4.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN92581.1 - 2.6e-06 26.9 0.1 6.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_M74 PF03411.8 KZN92581.1 - 0.089 12.0 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase DnaJ PF00226.26 KZN92582.1 - 1.2e-18 66.5 1.5 1.4e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain ATP-synt PF00231.14 KZN92583.1 - 2e-68 230.8 6.5 2.3e-68 230.6 4.5 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 KZN92584.1 - 2.5e-96 321.0 2.6 2.5e-96 321.0 1.8 3.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KZN92584.1 - 6.8e-82 274.0 5.7 6.8e-82 274.0 3.9 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KZN92584.1 - 4.1e-33 112.8 0.6 1.7e-32 110.8 0.4 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KZN92584.1 - 0.026 13.6 0.1 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ribosomal_S15 PF00312.17 KZN92584.1 - 4.4 7.1 11.0 0.14 11.9 1.1 2.9 2 1 1 3 3 3 0 Ribosomal protein S15 Epimerase PF01370.16 KZN92585.1 - 2.3e-19 69.7 0.0 3.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN92585.1 - 1.4e-06 27.2 0.0 5.9e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN92585.1 - 2.7e-06 27.4 0.0 7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KZN92585.1 - 4.5e-06 25.7 0.0 7.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KZN92585.1 - 1.2e-05 25.4 0.0 5.6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KZN92585.1 - 0.0037 16.9 0.0 0.041 13.5 0.0 2.1 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 KZN92585.1 - 0.0087 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KZN92585.1 - 0.091 11.7 0.0 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase AA_permease PF00324.16 KZN92586.1 - 2.5e-108 362.5 41.5 2.8e-108 362.3 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN92586.1 - 8.5e-27 93.7 45.6 1e-26 93.4 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.19 KZN92587.1 - 6e-21 74.9 0.2 8.9e-21 74.4 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KZN92587.1 - 1.1e-16 61.5 0.0 1.7e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M20 PF01546.23 KZN92588.1 - 1.3e-28 99.8 0.1 1.6e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KZN92588.1 - 7.9e-17 61.0 0.0 2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KZN92589.1 - 4.1e-59 200.1 3.8 5.2e-59 199.7 2.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 KZN92590.1 - 1.2e-147 492.0 0.0 1.5e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.15 KZN92591.1 - 1.3e-164 547.8 0.0 1.6e-164 547.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KZN92591.1 - 1.6e-10 40.9 0.2 3.2e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KZN92591.1 - 5e-07 29.7 0.0 3.4e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain DUF605 PF04652.11 KZN92592.1 - 2.8e-97 326.5 6.9 3.2e-97 326.3 4.8 1.0 1 0 0 1 1 1 1 Vta1 like Calpain_III PF01067.17 KZN92593.1 - 1.3e-22 80.0 0.0 5.4e-18 65.0 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KZN92593.1 - 2.5e-22 79.2 0.0 5.7e-22 78.0 0.0 1.5 1 1 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KZN92593.1 - 6.1e-06 26.0 6.8 1e-05 25.2 4.7 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 KZN92594.1 - 3e-55 183.9 1.1 8.4e-20 70.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 KZN92595.1 - 4.7e-16 59.1 0.3 6.8e-16 58.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN92595.1 - 2.1e-11 44.0 0.1 2.9e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN92595.1 - 2.3e-09 37.1 0.0 5.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN92595.1 - 3.2e-07 30.5 0.2 1e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN92595.1 - 7.4e-06 25.3 0.1 1.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KZN92595.1 - 0.00015 21.7 0.4 0.00039 20.3 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.14 KZN92595.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN92595.1 - 0.0062 16.0 0.3 0.028 13.8 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN92595.1 - 0.0097 14.8 0.2 0.13 11.1 0.1 2.4 2 1 0 2 2 2 1 Male sterility protein PseudoU_synth_2 PF00849.17 KZN92595.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase Zn_clus PF00172.13 KZN92596.1 - 4.9e-05 23.1 7.4 8.4e-05 22.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Allexi_40kDa PF05549.6 KZN92596.1 - 0.017 14.4 1.6 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Thioredoxin PF00085.15 KZN92597.1 - 1.6e-06 27.7 0.1 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin GNAT_acetyltr_2 PF13718.1 KZN92598.1 - 1.3e-78 262.8 0.0 2.2e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KZN92598.1 - 3.6e-66 222.1 0.0 1.1e-65 220.5 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KZN92598.1 - 1.1e-40 137.2 0.0 2.6e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KZN92598.1 - 2.4e-37 127.0 0.9 7.6e-37 125.4 0.7 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_19 PF13245.1 KZN92598.1 - 0.012 15.3 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_7 PF13508.1 KZN92598.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN92598.1 - 0.017 15.1 0.0 0.063 13.3 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_transf_90 PF05686.7 KZN92599.1 - 2e-11 43.2 0.2 0.0016 17.1 0.0 3.8 3 1 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_16 PF00722.16 KZN92600.1 - 4.9e-11 42.2 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.2 KZN92601.1 - 7.6e-72 240.6 0.0 1.3e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KZN92601.1 - 1.3e-06 28.0 0.0 0.033 13.7 0.0 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KZN92601.1 - 0.0044 16.8 0.4 0.0044 16.8 0.3 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KZN92601.1 - 0.03 14.3 1.8 0.034 14.1 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pox_D3 PF04580.8 KZN92601.1 - 0.056 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein Syntaxin-18_N PF10496.4 KZN92601.1 - 0.076 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus zf-RING_5 PF14634.1 KZN92601.1 - 3 7.6 3.7 0.9 9.3 0.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Condensation PF00668.15 KZN92602.1 - 0.0016 17.3 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain 2-oxoacid_dh PF00198.18 KZN92602.1 - 0.0077 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Transferase PF02458.10 KZN92602.1 - 0.029 12.8 0.1 0.043 12.2 0.0 1.4 1 1 0 1 1 1 0 Transferase family PI-PLC-X PF00388.14 KZN92603.1 - 0.0027 17.1 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Abhydrolase_5 PF12695.2 KZN92604.1 - 3.8e-05 23.4 0.1 0.0002 21.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN92604.1 - 0.00075 19.4 0.0 0.0044 16.9 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN92604.1 - 0.012 14.8 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KZN92604.1 - 0.027 14.0 0.4 0.055 13.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.5 KZN92604.1 - 0.04 12.7 0.0 0.086 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) FAA_hydrolase PF01557.13 KZN92605.1 - 6.9e-55 185.8 0.0 9.2e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SM-ATX PF14438.1 KZN92605.1 - 0.24 11.3 1.2 1.1 9.2 0.3 2.4 3 0 0 3 3 3 0 Ataxin 2 SM domain Glyoxalase PF00903.20 KZN92606.1 - 5.9e-13 48.9 4.8 8.7e-10 38.6 1.5 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KZN92606.1 - 2.8e-06 27.9 1.4 0.024 15.2 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KZN92606.1 - 0.00052 20.0 0.2 0.045 13.7 0.1 2.7 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.13 KZN92607.1 - 3.3e-05 22.8 0.1 4.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KZN92608.1 - 4.5e-67 226.6 0.0 5.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Peptidase_S9 PF00326.16 KZN92610.1 - 4.4e-53 179.6 0.0 7e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN92610.1 - 1.2e-09 38.1 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN92610.1 - 4.5e-08 33.2 0.0 9.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KZN92610.1 - 0.00061 19.3 1.8 0.0088 15.6 0.1 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KZN92610.1 - 0.021 13.4 0.0 0.093 11.3 0.0 2.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region COesterase PF00135.23 KZN92610.1 - 0.043 12.5 0.1 0.063 11.9 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF2920 PF11144.3 KZN92610.1 - 0.22 10.5 0.0 0.93 8.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) DNA_ligase_A_N PF04675.9 KZN92611.1 - 1e-55 188.2 0.0 1.8e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 KZN92611.1 - 1.9e-55 187.4 0.4 1.2e-53 181.4 0.3 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 KZN92611.1 - 1e-27 96.3 0.0 5.4e-26 90.8 0.0 2.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Nucleoporin_FG PF13634.1 KZN92611.1 - 0.23 11.6 8.7 0.63 10.2 6.0 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region DUF3677 PF12432.3 KZN92612.1 - 0.016 15.6 0.1 0.097 13.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) HEAT_EZ PF13513.1 KZN92612.1 - 0.27 11.7 6.0 0.87 10.1 0.3 4.0 3 0 0 3 3 3 0 HEAT-like repeat eIF-5_eIF-2B PF01873.12 KZN92613.1 - 6.1e-39 132.5 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KZN92613.1 - 7.9e-25 86.6 0.2 2.1e-24 85.2 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon HK PF02110.10 KZN92614.1 - 4.7e-75 251.9 0.1 8.4e-75 251.0 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KZN92614.1 - 1.1e-58 197.2 1.4 1.7e-58 196.6 0.9 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KZN92614.1 - 0.0003 20.1 0.0 0.00078 18.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KZN92614.1 - 0.011 14.9 0.8 0.051 12.7 0.0 2.4 3 1 0 3 3 3 0 Phosphomethylpyrimidine kinase Isochorismatase PF00857.15 KZN92615.1 - 1.7e-28 99.7 0.0 2.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3618 PF12277.3 KZN92615.1 - 0.071 13.1 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Med22 PF06179.7 KZN92618.1 - 8.8e-20 70.7 0.1 1.3e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DHFR_1 PF00186.14 KZN92619.1 - 1.6e-20 73.2 0.0 2.4e-13 49.9 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase Voltage_CLC PF00654.15 KZN92620.1 - 7.9e-93 311.2 24.2 1.7e-92 310.1 13.9 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel PqiA PF04403.8 KZN92620.1 - 0.001 18.6 1.3 0.0054 16.3 0.3 2.6 2 1 1 3 3 3 1 Paraquat-inducible protein A CBS PF00571.23 KZN92620.1 - 0.037 13.8 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 CBS domain Lipase_GDSL_2 PF13472.1 KZN92621.1 - 2.3e-24 86.5 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN92621.1 - 8.1e-20 71.6 0.0 9.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cwf_Cwc_15 PF04889.7 KZN92622.1 - 8.7e-83 277.7 11.7 9.6e-83 277.6 8.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 KZN92622.1 - 0.0019 17.6 3.6 0.0025 17.3 2.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 KZN92622.1 - 7.5 4.4 16.6 9 4.1 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_PH PF01138.16 KZN92623.1 - 2e-17 63.7 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KZN92623.1 - 2.4e-05 24.1 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HAD PF12710.2 KZN92624.1 - 8.3e-18 65.2 0.1 2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KZN92624.1 - 4e-16 58.7 0.1 6.8e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN92624.1 - 2.4e-14 54.2 0.1 2e-13 51.2 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN92624.1 - 8.7e-12 44.8 0.0 2.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KZN92624.1 - 0.0039 16.7 0.3 0.014 14.9 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN92624.1 - 0.017 15.3 0.1 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DNA_pol_lambd_f PF10391.4 KZN92625.1 - 9.1e-23 79.5 0.6 1.6e-22 78.7 0.4 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KZN92625.1 - 7.5e-19 67.1 0.1 3e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KZN92625.1 - 8e-15 54.8 0.2 2.6e-14 53.2 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KZN92625.1 - 2.3e-09 37.2 0.0 9.7e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KZN92625.1 - 0.00023 21.2 0.0 0.0035 17.4 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KZN92625.1 - 0.0054 17.0 0.1 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2759 PF10958.3 KZN92626.1 - 9.6 5.8 6.0 0.98 9.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) NicO PF03824.11 KZN92627.1 - 1e-57 195.6 22.4 3.8e-55 187.2 5.3 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein IncA PF04156.9 KZN92627.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.2 3 0 0 3 3 3 0 IncA protein ATP-synt_B PF00430.13 KZN92627.1 - 0.17 11.6 0.1 17 5.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) MIG-14_Wnt-bd PF06664.7 KZN92627.1 - 0.2 10.4 8.8 0.054 12.3 3.2 1.9 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Peptidase_M14 PF00246.19 KZN92629.1 - 1.7e-72 244.3 0.0 2.1e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 KZN92630.1 - 8.1e-38 129.9 0.0 1.6e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KZN92630.1 - 7.6e-05 22.8 0.3 0.00018 21.6 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KZN92630.1 - 0.0081 16.3 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 PH domain p450 PF00067.17 KZN92630.1 - 0.011 14.2 0.2 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome P450 zf-C3HC4_2 PF13923.1 KZN92631.1 - 1.1e-07 31.7 14.5 0.00014 21.7 2.4 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN92631.1 - 1.6e-05 24.5 12.5 0.0088 15.8 4.5 2.5 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.7 KZN92631.1 - 0.00018 20.7 13.6 0.00048 19.3 0.7 3.0 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_5 PF14634.1 KZN92631.1 - 0.00032 20.3 7.7 0.00032 20.3 5.3 2.6 2 1 0 2 2 2 1 zinc-RING finger domain Atg14 PF10186.4 KZN92631.1 - 0.0011 18.0 1.6 0.0019 17.1 1.1 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FYVE PF01363.16 KZN92631.1 - 0.0026 17.6 11.1 0.049 13.5 3.6 3.6 2 1 1 3 3 3 2 FYVE zinc finger zf-C3HC4 PF00097.20 KZN92631.1 - 0.0034 17.0 5.1 0.0034 17.0 3.5 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KZN92631.1 - 0.0085 15.7 5.4 0.0085 15.7 3.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Vps39_2 PF10367.4 KZN92631.1 - 0.03 14.4 1.2 0.03 14.4 0.9 3.2 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 IBR PF01485.16 KZN92631.1 - 7.9 6.4 11.5 7 6.5 0.4 3.4 3 1 0 3 3 3 0 IBR domain Endonuclease_NS PF01223.18 KZN92632.1 - 5.9e-60 202.4 0.0 9.6e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.17 KZN92633.1 - 7.9e-28 97.3 16.8 4.2e-27 94.9 11.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter PAD_N PF08526.5 KZN92633.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain AAA_16 PF13191.1 KZN92635.1 - 6.6e-10 39.2 0.2 3.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KZN92635.1 - 1.2e-05 25.4 0.1 0.00029 20.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain TPR_12 PF13424.1 KZN92635.1 - 0.00022 21.0 18.4 0.44 10.5 0.2 8.0 8 1 0 8 8 8 3 Tetratricopeptide repeat NACHT PF05729.7 KZN92635.1 - 0.00024 20.8 0.0 0.0012 18.5 0.0 2.2 1 0 0 1 1 1 1 NACHT domain Shikimate_DH PF01488.15 KZN92635.1 - 0.025 14.6 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TPR_7 PF13176.1 KZN92635.1 - 0.059 13.1 4.8 2.1 8.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_17 PF13207.1 KZN92635.1 - 0.13 13.0 0.0 0.7 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_S30 PF04758.9 KZN92636.1 - 6.8e-28 96.1 6.3 7.9e-28 95.9 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DUF2040 PF09745.4 KZN92637.1 - 4.3e-39 133.2 16.9 4.3e-39 133.2 11.7 3.6 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Sedlin_N PF04628.8 KZN92638.1 - 9.1e-41 138.8 0.0 1.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KZN92638.1 - 0.00094 18.9 0.0 0.0043 16.7 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family Isochorismatase PF00857.15 KZN92639.1 - 5.1e-43 147.0 0.0 1.9e-42 145.1 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 KZN92639.1 - 7.5e-07 29.5 0.0 1.3e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 KZN92639.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT NUDE_C PF04880.8 KZN92640.1 - 1.9e-32 112.8 6.6 1.9e-32 112.8 4.6 4.1 3 1 1 4 4 4 1 NUDE protein, C-terminal conserved region ATG16 PF08614.6 KZN92640.1 - 0.19 11.5 31.9 0.14 12.0 12.4 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF745 PF05335.8 KZN92640.1 - 0.51 9.8 8.2 0.93 8.9 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Filament PF00038.16 KZN92640.1 - 0.62 9.4 30.0 3.8 6.8 8.7 2.8 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin_1 PF12718.2 KZN92640.1 - 1.5 8.6 32.2 0.56 10.0 14.6 3.3 2 1 1 3 3 3 0 Tropomyosin like Tho2 PF11262.3 KZN92640.1 - 4.2 6.3 16.6 1.7 7.6 2.3 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF904 PF06005.7 KZN92640.1 - 6.1 7.2 34.5 0.028 14.6 5.7 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF904) Peptidase_S46 PF10459.4 KZN92640.1 - 7.6 4.8 14.5 9.5 4.4 10.0 1.1 1 0 0 1 1 1 0 Peptidase S46 ADIP PF11559.3 KZN92640.1 - 8.8 6.2 31.8 0.8 9.6 3.0 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ACC_central PF08326.7 KZN92641.1 - 3.9e-259 861.5 0.0 5e-259 861.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KZN92641.1 - 3.6e-179 596.2 0.0 6.7e-179 595.3 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KZN92641.1 - 5.4e-52 176.1 0.0 1.1e-51 175.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KZN92641.1 - 7.7e-24 83.9 0.1 1.5e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KZN92641.1 - 2.5e-23 82.0 0.0 1.2e-19 70.2 0.0 3.5 4 0 0 4 4 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KZN92641.1 - 4.5e-16 58.2 0.1 1.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KZN92641.1 - 2.6e-11 43.5 0.0 6.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN92641.1 - 6.5e-08 31.6 0.0 0.019 13.7 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KZN92641.1 - 5.4e-05 22.6 0.0 0.00013 21.3 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KZN92641.1 - 0.00036 20.4 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 KZN92641.1 - 0.19 11.1 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain MFS_1 PF07690.11 KZN92643.1 - 1.7e-30 105.9 62.2 1.2e-29 103.1 40.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3753 PF12575.3 KZN92643.1 - 0.57 10.0 6.9 4.1 7.2 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Glyoxalase_2 PF12681.2 KZN92644.1 - 1.7e-05 25.3 0.0 2.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain F-box-like PF12937.2 KZN92645.1 - 5.3e-07 29.2 0.3 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN92645.1 - 0.084 12.5 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 F-box domain SDA1 PF05285.7 KZN92645.1 - 1.3 8.2 10.1 1.8 7.7 7.0 1.1 1 0 0 1 1 1 0 SDA1 DUF3669 PF12417.3 KZN92646.1 - 1.2e-20 73.0 0.3 3e-20 71.7 0.2 1.7 1 0 0 1 1 1 1 Zinc finger protein Peptidase_S64 PF08192.6 KZN92647.1 - 0.013 13.8 0.1 0.082 11.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 RINGv PF12906.2 KZN92648.1 - 6.5e-16 58.1 9.8 1.1e-15 57.4 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.1 KZN92648.1 - 0.18 11.5 5.5 0.31 10.7 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KZN92648.1 - 0.46 10.0 6.3 0.77 9.3 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 KZN92648.1 - 0.57 10.0 9.5 1 9.2 6.6 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KZN92648.1 - 0.8 9.7 6.1 1.6 8.7 4.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF788 PF05620.6 KZN92650.1 - 3.5e-46 157.1 0.0 4e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_1 PF00515.23 KZN92651.1 - 1.1e-45 151.3 17.3 3.9e-08 32.5 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 KZN92651.1 - 2e-41 136.5 18.9 1.6e-05 24.4 0.2 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 KZN92651.1 - 5.1e-40 134.9 27.0 3e-11 42.7 2.0 7.7 5 1 2 8 8 8 7 TPR repeat TPR_16 PF13432.1 KZN92651.1 - 2.7e-30 104.3 24.6 1.5e-08 35.0 0.1 8.6 7 2 1 8 8 8 7 Tetratricopeptide repeat Apc3 PF12895.2 KZN92651.1 - 3.4e-28 97.6 18.9 5.8e-19 68.0 0.7 4.5 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KZN92651.1 - 6.4e-28 94.4 0.0 0.0016 18.0 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KZN92651.1 - 5e-23 80.8 20.3 4.7e-05 23.2 0.4 7.7 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92651.1 - 1.2e-22 79.9 9.3 3.4e-07 30.5 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92651.1 - 1.2e-20 72.0 6.9 0.088 13.4 0.0 9.2 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92651.1 - 2.3e-13 49.1 13.6 0.05 13.8 0.0 9.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92651.1 - 2.5e-13 48.7 2.6 0.0026 17.4 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KZN92651.1 - 2.9e-10 39.9 3.3 0.75 10.3 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 KZN92651.1 - 0.00038 20.4 5.1 0.014 15.3 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN92651.1 - 0.0083 15.9 7.5 12 5.8 0.1 5.8 4 1 4 8 8 8 0 Tetratricopeptide repeat MIT PF04212.13 KZN92651.1 - 0.043 13.7 2.7 2.5 8.0 0.1 4.3 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 KZN92651.1 - 0.16 10.6 0.6 10 4.7 0.1 2.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) APP_E2 PF12925.2 KZN92651.1 - 0.23 11.0 2.5 0.27 10.7 0.3 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein DUF2225 PF09986.4 KZN92651.1 - 7.4 5.9 12.0 2.1 7.7 0.1 4.1 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) Acyltransferase PF01553.16 KZN92652.1 - 2e-31 108.1 0.0 3.3e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.15 KZN92653.1 - 3.5e-09 36.4 0.0 1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 KZN92654.1 - 6.9e-55 185.5 0.0 6.6e-45 153.0 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KZN92654.1 - 2.3e-09 37.0 0.0 1.9e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KZN92654.1 - 0.00026 20.4 0.0 0.0019 17.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KZN92654.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KZN92654.1 - 0.027 13.7 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative amidotransferase RRM_1 PF00076.17 KZN92655.1 - 7.3e-16 57.5 0.0 1.1e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN92655.1 - 1.4e-11 44.1 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN92655.1 - 2.3e-08 33.7 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OTT_1508_deam PF14441.1 KZN92655.1 - 0.13 12.0 0.2 0.28 10.9 0.2 1.7 1 1 0 1 1 1 0 OTT_1508-like deaminase TACC PF05010.9 KZN92656.1 - 1.9e-05 24.5 2.3 4e-05 23.4 1.6 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Macoilin PF09726.4 KZN92656.1 - 0.043 12.1 1.2 0.093 11.0 0.9 1.5 1 0 0 1 1 1 0 Transmembrane protein TFIIIC_delta PF12657.2 KZN92656.1 - 0.85 9.3 6.4 4.2 7.0 0.1 3.2 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term GSG-1 PF07803.6 KZN92657.1 - 0.11 12.0 0.2 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 GSG1-like protein Rotamase PF00639.16 KZN92659.1 - 6.8e-23 81.2 0.1 9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KZN92659.1 - 7.2e-15 55.2 0.0 8.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KZN92659.1 - 3e-10 39.7 1.1 3e-10 39.7 0.8 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KZN92659.1 - 1.1e-05 25.9 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain TFIIS_C PF01096.13 KZN92660.1 - 5.2e-14 51.5 3.3 5.2e-14 51.5 2.3 3.4 5 0 0 5 5 5 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KZN92660.1 - 2.3e-10 39.9 1.4 2.3e-10 39.9 1.0 3.7 4 1 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 KZN92660.1 - 0.037 14.3 3.0 0.037 14.3 2.1 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar GFA PF04828.9 KZN92660.1 - 3.2 7.7 17.5 0.55 10.2 0.6 3.5 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L14 PF00238.14 KZN92661.1 - 3.2e-45 152.8 1.8 3.6e-45 152.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FlgH PF02107.11 KZN92661.1 - 0.077 12.5 0.1 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein SET PF00856.23 KZN92662.1 - 5.1e-10 39.8 0.0 1.1e-07 32.2 0.0 2.9 2 0 0 2 2 2 2 SET domain IER PF05760.7 KZN92662.1 - 0.015 15.2 2.2 0.015 15.2 1.5 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) COesterase PF00135.23 KZN92663.1 - 2.8e-78 263.9 0.3 6.2e-78 262.8 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN92663.1 - 1.2e-05 24.9 0.4 0.0002 21.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN92663.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.24 KZN92664.1 - 2e-30 105.5 0.2 5.2e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN92664.1 - 4.1e-16 58.6 0.0 1e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN92664.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KZN92664.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain Anillin PF08174.6 KZN92665.1 - 9.2e-29 100.2 0.4 3.2e-28 98.5 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KZN92665.1 - 1.1e-07 31.9 0.0 4.3e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 PH domain Kelch_3 PF13415.1 KZN92666.1 - 2.5e-34 116.6 5.7 3.6e-07 30.1 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KZN92666.1 - 1.3e-28 98.4 9.1 3.4e-12 45.9 0.1 6.0 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KZN92666.1 - 1.6e-20 72.3 1.6 0.00042 20.3 0.0 6.2 4 2 2 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KZN92666.1 - 1.1e-14 53.9 0.5 0.0016 18.3 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KZN92666.1 - 8.8e-12 44.2 6.8 0.00034 20.2 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KZN92666.1 - 2.2e-11 43.0 0.0 0.16 11.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif ASFV_J13L PF05568.6 KZN92666.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF829 PF05705.9 KZN92668.1 - 1.2e-57 195.4 0.1 1.3e-57 195.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KZN92668.1 - 0.0076 16.1 0.1 0.013 15.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KZN92669.1 - 4.6e-17 61.7 1.2 4.6e-17 61.7 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Acyl_transf_3 PF01757.17 KZN92670.1 - 1.5e-20 73.3 24.6 7.3e-20 71.0 17.1 2.0 1 1 0 1 1 1 1 Acyltransferase family HS1_rep PF02218.10 KZN92671.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 1 0 1 1 1 0 Repeat in HS1/Cortactin DUF202 PF02656.10 KZN92674.1 - 2.9e-17 62.6 0.6 2.9e-17 62.6 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2818 PF10993.3 KZN92674.1 - 0.037 14.5 0.8 0.097 13.1 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) EpsG PF14897.1 KZN92674.1 - 0.11 11.4 1.5 0.13 11.1 1.1 1.1 1 0 0 1 1 1 0 EpsG family Sarcoglycan_1 PF04790.8 KZN92674.1 - 0.21 10.7 1.7 9.6 5.2 0.3 2.2 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein PIG-Y PF15159.1 KZN92674.1 - 0.22 11.7 2.5 0.74 10.0 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Tic20 PF09685.5 KZN92674.1 - 0.22 11.4 5.9 7 6.6 4.1 2.2 1 1 0 1 1 1 0 Tic20-like protein DAO PF01266.19 KZN92675.1 - 6.5e-65 219.3 0.5 9.7e-65 218.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 KZN92675.1 - 5.5e-56 189.2 0.0 8.9e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KZN92675.1 - 2.1e-18 66.1 0.0 5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 KZN92675.1 - 1.2e-05 25.4 0.0 0.00012 22.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN92675.1 - 0.00018 21.8 1.6 0.0079 16.5 0.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.7 KZN92675.1 - 0.00049 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.13 KZN92675.1 - 0.0024 17.8 0.1 0.01 15.7 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 KZN92675.1 - 0.0037 17.0 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.16 KZN92675.1 - 0.0048 16.7 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 ThiF family NAD_binding_8 PF13450.1 KZN92675.1 - 0.016 15.2 0.0 0.063 13.2 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KZN92675.1 - 0.017 14.1 0.5 0.22 10.5 0.3 2.1 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KZN92675.1 - 0.03 14.2 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KZN92675.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1962 PF09227.5 KZN92675.1 - 0.11 12.5 0.3 0.31 11.1 0.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1962) MFS_1 PF07690.11 KZN92677.1 - 7.9e-13 47.8 48.0 5.7e-12 45.0 32.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_DE_N PF02823.11 KZN92678.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain p450 PF00067.17 KZN92679.1 - 7.5e-60 202.7 0.0 1e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UDP-g_GGTase PF06427.6 KZN92679.1 - 0.021 14.1 0.3 0.038 13.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase DRAT PF07357.6 KZN92679.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Prok-E2_A PF14457.1 KZN92679.1 - 0.071 12.5 0.4 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A TFIIE_alpha PF02002.12 KZN92680.1 - 1.2e-16 60.1 0.0 2.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit PseudoU_synth_1 PF01416.15 KZN92681.1 - 2.7e-22 79.1 0.1 3.9e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pex14_N PF04695.8 KZN92681.1 - 3 7.8 8.0 9.1 6.3 5.5 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3517 PF12030.3 KZN92682.1 - 2.2e-91 305.9 0.0 3.8e-91 305.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 KZN92682.1 - 5e-45 153.7 0.1 1e-44 152.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KZN92682.1 - 1.5e-17 64.0 0.0 3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hexapep PF00132.19 KZN92683.1 - 8.2e-15 53.5 6.9 7.8e-12 44.1 2.3 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KZN92683.1 - 9.7e-14 50.6 6.7 1.9e-11 43.3 1.9 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KZN92683.1 - 5.8e-13 48.6 0.2 9.5e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.9 KZN92684.1 - 4.2e-27 94.1 1.1 7.7e-27 93.3 0.8 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KZN92684.1 - 2.4e-12 46.8 3.9 2.4e-12 46.8 2.7 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KZN92684.1 - 1.6e-07 30.8 1.1 2.3e-07 30.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KZN92684.1 - 0.16 11.7 4.8 0.082 12.6 2.1 1.5 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Tmemb_170 PF10190.4 KZN92686.1 - 3.6e-05 23.7 7.6 4.6e-05 23.4 5.2 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF3397 PF11877.3 KZN92686.1 - 1.9 8.5 12.6 3.5 7.6 6.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) WD40 PF00400.27 KZN92687.1 - 4.9e-48 159.3 27.2 6.6e-09 35.3 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KZN92687.1 - 0.002 17.8 0.2 0.42 10.2 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 KZN92687.1 - 0.15 12.2 0.0 0.5 10.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes MBOAT PF03062.14 KZN92688.1 - 2.6e-23 82.6 16.4 5.3e-23 81.6 11.4 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KZN92688.1 - 0.023 14.7 3.1 0.068 13.2 2.2 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family MAPEG PF01124.13 KZN92689.1 - 4.1e-26 91.0 1.7 4.9e-26 90.8 1.1 1.0 1 0 0 1 1 1 1 MAPEG family DUF2613 PF11021.3 KZN92689.1 - 0.11 12.2 3.1 0.19 11.4 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) OMPdecase PF00215.19 KZN92690.1 - 8.9e-78 260.7 0.0 1e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PGK PF00162.14 KZN92690.1 - 0.034 12.6 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase MFS_1 PF07690.11 KZN92691.1 - 5.9e-39 133.7 22.6 7.8e-39 133.3 14.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PIRT PF15099.1 KZN92691.1 - 0.064 12.4 5.6 0.061 12.5 0.6 2.5 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family NfeD PF01957.13 KZN92691.1 - 1.1 9.4 12.1 6.2 6.9 0.0 3.9 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding S4 PF01479.20 KZN92693.1 - 6.4e-14 51.1 0.0 1.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KZN92693.1 - 5.6e-06 26.6 3.3 9e-06 25.9 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Occludin_ELL PF07303.8 KZN92693.1 - 0.0088 16.7 0.1 0.021 15.5 0.1 1.7 1 0 0 1 1 1 1 Occludin homology domain COG2 PF06148.6 KZN92693.1 - 0.05 13.4 0.2 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Clr5 PF14420.1 KZN92694.1 - 5.6e-11 42.1 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain Sigma54_DBD PF04552.8 KZN92694.1 - 8.1e-05 22.1 0.5 0.0036 16.8 0.0 2.3 1 1 1 2 2 2 1 Sigma-54, DNA binding domain rve PF00665.21 KZN92694.1 - 0.0058 16.7 0.4 4.7 7.3 0.0 2.6 2 1 0 2 2 2 2 Integrase core domain HTH_12 PF08461.5 KZN92694.1 - 0.065 12.9 0.1 3.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 KZN92694.1 - 0.15 12.0 4.1 0.62 10.1 0.1 3.1 2 1 1 3 3 3 0 HTH-like domain ketoacyl-synt PF00109.21 KZN92695.1 - 6.6e-70 235.4 0.0 5e-69 232.5 0.0 2.6 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN92695.1 - 7e-59 198.5 0.2 1.6e-58 197.3 0.2 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KZN92695.1 - 2e-57 194.6 0.0 3.6e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN92695.1 - 2.1e-51 175.1 0.0 3.7e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KZN92695.1 - 7.9e-43 146.2 0.0 3.3e-42 144.2 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN92695.1 - 6.1e-34 116.4 0.0 1.3e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KZN92695.1 - 4e-18 65.6 0.0 2e-17 63.4 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN92695.1 - 6.2e-13 48.7 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KZN92695.1 - 1.9e-12 46.8 0.0 4.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KZN92695.1 - 7.3e-10 39.4 0.0 9.9e-09 35.7 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92695.1 - 1.5e-08 34.3 0.0 3.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN92695.1 - 7.3e-07 29.5 0.0 1.9e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KZN92695.1 - 5.8e-06 26.4 0.1 1.5e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NodS PF05401.6 KZN92695.1 - 1.7e-05 24.2 0.0 4.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) Thiolase_N PF00108.18 KZN92695.1 - 0.00034 19.7 0.0 0.00077 18.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KZN92695.1 - 0.00091 18.4 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KZN92695.1 - 0.0044 16.4 0.1 0.21 10.9 0.0 2.8 3 0 0 3 3 3 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.7 KZN92695.1 - 0.0066 16.1 0.1 0.022 14.5 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 KZN92695.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DnaJ PF00226.26 KZN92696.1 - 2.5e-24 84.7 1.6 4.1e-24 84.0 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KZN92696.1 - 8.4e-17 60.9 15.6 1.4e-16 60.2 10.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KZN92696.1 - 7.1e-11 41.8 0.0 6.2e-09 35.6 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 KZN92696.1 - 0.12 12.0 7.7 0.72 9.5 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 KZN92696.1 - 1.3 8.9 5.8 3.3 7.6 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Lar_restr_allev PF14354.1 KZN92696.1 - 3.2 8.1 8.7 6.2 7.2 0.1 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar Cytochrom_c3_2 PF14537.1 KZN92696.1 - 3.4 8.0 12.1 2.2 8.7 2.8 2.0 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KZN92696.1 - 5.2 6.7 11.7 31 4.3 8.2 2.2 1 1 0 1 1 1 0 Cytochrome c7 Tricorn_C1 PF14684.1 KZN92697.1 - 0.0014 18.4 0.2 0.022 14.6 0.1 2.8 3 0 0 3 3 3 1 Tricorn protease C1 domain DUF4449 PF14613.1 KZN92697.1 - 0.0025 17.7 0.1 0.0025 17.7 0.1 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF4449) Malic_M PF03949.10 KZN92698.1 - 3e-84 282.5 0.0 4.1e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KZN92698.1 - 2.3e-63 213.0 0.0 6.6e-63 211.5 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Oxidored_FMN PF00724.15 KZN92699.1 - 1.3e-51 175.6 0.0 1.6e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KZN92699.1 - 0.0089 15.3 0.1 0.51 9.5 0.0 2.6 1 1 0 2 2 2 1 Xylose isomerase-like TIM barrel HLH PF00010.21 KZN92700.1 - 0.01 15.5 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain EGF_3 PF12947.2 KZN92700.1 - 2.5 8.1 4.7 48 4.0 3.2 2.3 1 1 0 1 1 1 0 EGF domain Fungal_trans PF04082.13 KZN92701.1 - 7.4e-31 106.9 0.1 1.7e-30 105.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92701.1 - 2.6e-07 30.4 7.2 6.3e-07 29.1 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92702.1 - 5.7e-33 113.8 2.1 8.9e-33 113.2 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92702.1 - 1.7e-08 34.1 13.3 2.8e-08 33.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN92703.1 - 9.6e-49 165.9 44.2 4.5e-46 157.1 32.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN92703.1 - 1.3e-14 53.3 17.1 1.3e-14 53.3 11.8 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN92703.1 - 9.4e-11 40.9 14.6 9.4e-11 40.9 10.1 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter DBD_Tnp_Mut PF03108.10 KZN92704.1 - 1.2e-11 44.0 0.9 2.3e-11 43.0 0.6 1.4 1 0 0 1 1 1 1 MuDR family transposase PAT1 PF09770.4 KZN92704.1 - 0.92 7.6 11.1 1.1 7.3 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THOC7 PF05615.8 KZN92705.1 - 2.6e-37 128.2 8.7 2.6e-37 128.2 6.0 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 KZN92705.1 - 0.016 15.2 8.0 0.013 15.5 1.3 2.3 1 1 2 3 3 3 0 Zinc finger-containing protein DUF4600 PF15372.1 KZN92705.1 - 0.045 13.9 9.8 0.084 13.0 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) CHASE3 PF05227.8 KZN92705.1 - 0.064 12.9 11.9 0.021 14.4 4.4 2.4 1 1 1 2 2 2 0 CHASE3 domain FUSC PF04632.7 KZN92705.1 - 3.5 5.9 5.9 4 5.7 4.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.11 KZN92706.1 - 3e-24 84.9 9.2 3.8e-24 84.5 6.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Prominin PF05478.6 KZN92706.1 - 0.01 13.4 4.4 0.011 13.3 3.0 1.0 1 0 0 1 1 1 0 Prominin Aida_N PF08910.5 KZN92706.1 - 0.098 12.9 1.4 0.22 11.7 1.0 1.5 1 1 0 1 1 1 0 Aida N-terminus Uso1_p115_C PF04871.8 KZN92706.1 - 0.23 11.4 9.7 0.34 10.8 6.7 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region RRF_GI PF12614.3 KZN92706.1 - 0.27 11.0 3.2 0.43 10.4 2.2 1.5 1 1 0 1 1 1 0 Ribosome recycling factor CENP-Q PF13094.1 KZN92706.1 - 0.54 10.2 11.7 2.2 8.2 8.1 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-C4H2 PF10146.4 KZN92706.1 - 0.95 9.4 8.6 1.2 9.1 6.0 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Fib_alpha PF08702.5 KZN92706.1 - 2.7 8.0 7.3 3.4 7.7 5.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 KZN92706.1 - 6 7.2 9.3 2.6 8.3 3.3 2.0 1 1 0 2 2 2 0 Spectrin repeat Elongin_A PF06881.6 KZN92707.1 - 2.7e-26 92.0 0.1 4.7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 KZN92708.1 - 9.3e-25 85.8 0.0 1e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KZN92708.1 - 6.8e-16 57.7 0.0 7.5e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KZN92708.1 - 0.00035 20.7 0.0 0.0014 18.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain LigT_PEase PF02834.11 KZN92709.1 - 0.011 15.7 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase Syntaxin-18_N PF10496.4 KZN92709.1 - 0.15 11.8 0.4 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ribosomal_L44 PF00935.14 KZN92710.1 - 1.3e-27 95.6 6.1 1.8e-27 95.1 4.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Sugar_tr PF00083.19 KZN92711.1 - 5.9e-84 282.2 30.9 6.7e-84 282.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92711.1 - 3e-28 98.5 27.6 1.5e-27 96.2 17.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN92712.1 - 1.4e-14 53.6 0.3 2.5e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92712.1 - 9.4e-08 31.8 6.2 1.7e-07 31.0 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4588 PF15251.1 KZN92712.1 - 0.031 14.2 4.7 0.074 13.0 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Dickkopf_N PF04706.7 KZN92712.1 - 1.3 9.2 11.2 0.29 11.3 5.2 1.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Acetyltransf_7 PF13508.1 KZN92713.1 - 2.3e-06 27.6 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN92713.1 - 4.2e-06 26.7 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KZN92713.1 - 0.033 14.3 0.0 0.057 13.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Phosphoesterase PF04185.9 KZN92715.1 - 3.6e-67 227.1 0.8 5.5e-67 226.5 0.6 1.3 1 1 0 1 1 1 1 Phosphoesterase family DUF3824 PF12868.2 KZN92716.1 - 1.5e-49 168.4 29.5 1.5e-49 168.4 20.5 8.8 4 3 4 8 8 8 1 Domain of unknwon function (DUF3824) DUF3681 PF12442.3 KZN92716.1 - 0.46 10.6 4.0 2.9 8.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) DUF2910 PF11139.3 KZN92716.1 - 3.6 6.6 8.9 34 3.4 4.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2910) Vac7 PF12751.2 KZN92717.1 - 1e-204 679.6 3.3 1e-204 679.6 2.3 1.9 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 CorA PF01544.13 KZN92720.1 - 7.1e-30 104.0 3.9 1e-18 67.4 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein TIM-br_sig_trns PF09370.5 KZN92721.1 - 1e-134 447.7 1.0 1.2e-134 447.5 0.7 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 KZN92721.1 - 0.00029 20.0 0.4 0.00029 20.0 0.2 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase DUF3573 PF12097.3 KZN92722.1 - 0.79 8.2 2.4 1.4 7.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Adenylate_cycl PF01295.13 KZN92722.1 - 0.85 7.8 3.3 1.4 7.0 2.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase, class-I Reo_sigmaC PF04582.7 KZN92722.1 - 0.86 8.7 10.6 1.2 8.2 6.0 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein adh_short PF00106.20 KZN92723.1 - 9.6e-27 93.9 0.3 1e-25 90.5 0.1 2.2 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN92723.1 - 2.1e-10 40.7 0.0 3.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN92723.1 - 2.4e-10 40.3 0.8 2.7e-08 33.6 0.3 2.7 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN92723.1 - 0.00042 20.3 0.1 0.0031 17.5 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding TilS PF09179.6 KZN92723.1 - 0.021 14.8 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 TilS substrate binding domain Epimerase PF01370.16 KZN92723.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KZN92724.1 - 3.7e-10 39.5 11.6 3.7e-10 39.5 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92724.1 - 0.0029 16.5 0.1 0.0074 15.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRN7 PF11781.3 KZN92724.1 - 0.41 10.1 5.2 0.92 9.0 3.6 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Alpha_GJ PF03229.8 KZN92726.1 - 0.0038 17.5 2.3 0.0038 17.5 1.6 2.4 2 0 0 2 2 2 1 Alphavirus glycoprotein J Herpes_gE PF02480.11 KZN92726.1 - 0.0076 14.5 0.3 0.014 13.7 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KZN92726.1 - 0.035 12.9 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3554 PF12074.3 KZN92727.1 - 1.1e-101 340.6 5.7 1.4e-101 340.3 1.4 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KZN92727.1 - 2.1e-58 196.2 8.7 5.9e-58 194.8 6.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.17 KZN92727.1 - 6.1e-37 122.3 32.4 0.016 15.2 0.0 22.3 24 0 0 24 24 24 7 HEAT repeat HEAT_2 PF13646.1 KZN92727.1 - 7.3e-31 106.3 53.4 5.6e-09 36.1 0.1 15.6 10 3 5 15 15 15 7 HEAT repeats HEAT_EZ PF13513.1 KZN92727.1 - 4.3e-25 87.5 64.6 2.9e-05 24.4 0.1 23.7 21 4 7 28 28 27 9 HEAT-like repeat Cnd1 PF12717.2 KZN92727.1 - 7.6e-11 42.1 0.0 0.034 13.9 0.0 8.1 8 1 1 10 10 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KZN92727.1 - 2.9e-10 40.3 0.0 1.5 9.2 0.0 7.9 6 2 2 8 8 8 2 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KZN92727.1 - 5.1e-09 36.2 2.4 0.035 13.9 0.0 6.1 7 1 0 7 7 7 2 Parkin co-regulated protein CLASP_N PF12348.3 KZN92727.1 - 3.4e-07 29.8 0.0 0.5 9.6 0.0 7.2 6 1 2 8 8 8 1 CLASP N terminal Vitellogenin_N PF01347.17 KZN92727.1 - 0.13 10.4 0.0 0.29 9.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein amino terminal region MMS19_C PF12460.3 KZN92727.1 - 1.8 7.2 17.2 1.8 7.2 0.5 6.3 8 0 0 8 8 8 0 RNAPII transcription regulator C-terminal HA2 PF04408.18 KZN92728.1 - 8.1e-19 67.5 0.0 2.3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN92728.1 - 1.1e-13 50.8 0.3 3.5e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN92728.1 - 8.6e-10 38.3 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN92728.1 - 8.1e-07 29.2 0.0 4.2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF3602 PF12223.3 KZN92728.1 - 0.0014 18.9 0.0 0.0077 16.5 0.0 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) KilA-N PF04383.8 KZN92729.1 - 0.00043 19.8 0.0 0.0065 16.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Abhydrolase_6 PF12697.2 KZN92731.1 - 5e-30 105.0 0.2 6.5e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN92731.1 - 6e-11 42.3 0.2 1.5e-10 40.9 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN92731.1 - 0.00077 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KZN92731.1 - 0.0035 16.9 0.0 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein PTCB-BRCT PF12738.2 KZN92732.1 - 0.084 12.7 3.7 0.18 11.7 0.1 2.6 2 0 0 2 2 2 0 twin BRCT domain Mg_trans_NIPA PF05653.9 KZN92733.1 - 5.5e-90 301.3 25.6 7.8e-90 300.8 17.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KZN92733.1 - 2.2e-06 27.8 8.3 2.2e-06 27.8 5.8 3.3 1 1 2 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KZN92733.1 - 5.9e-06 26.3 6.2 5.9e-06 26.3 4.3 3.2 3 1 0 3 3 3 1 EamA-like transporter family Patatin PF01734.17 KZN92734.1 - 1.4e-27 96.9 0.0 2.9e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.12 KZN92735.1 - 1.8e-17 63.0 0.0 2.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KZN92735.1 - 2.9e-13 49.5 0.0 5.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain APH PF01636.18 KZN92736.1 - 2.3e-14 53.6 0.1 7.8e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN92736.1 - 1.8e-06 27.6 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN92736.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SHMT PF00464.14 KZN92737.1 - 3.8e-198 657.7 0.0 4.5e-198 657.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KZN92737.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Flocculin_t3 PF13928.1 KZN92739.1 - 0.014 15.5 7.3 0.014 15.5 5.1 2.8 1 1 2 3 3 3 0 Flocculin type 3 repeat Presenilin PF01080.12 KZN92740.1 - 1.9 7.2 4.5 2.5 6.8 3.1 1.1 1 0 0 1 1 1 0 Presenilin FA_hydroxylase PF04116.8 KZN92741.1 - 5.8e-15 55.6 10.5 5.8e-15 55.6 7.3 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Hemagglutinin PF00509.13 KZN92742.1 - 0.11 10.6 0.7 0.16 10.0 0.5 1.1 1 0 0 1 1 1 0 Haemagglutinin Fungal_trans_2 PF11951.3 KZN92744.1 - 4.2e-21 74.9 6.3 1.7e-20 72.9 4.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92744.1 - 3.4e-07 30.0 12.2 3.4e-07 30.0 8.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KZN92745.1 - 9.1e-104 347.5 22.3 1.1e-103 347.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92745.1 - 1.2e-18 66.9 35.8 2.1e-15 56.3 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KZN92745.1 - 0.0054 14.8 0.6 0.0054 14.8 0.4 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3917 PF13055.1 KZN92745.1 - 0.015 15.5 0.4 0.089 13.0 0.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) adh_short_C2 PF13561.1 KZN92746.1 - 1.4e-27 97.0 0.0 1.8e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN92746.1 - 1.7e-22 80.1 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN92746.1 - 1.4e-14 54.2 0.1 1.9e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF3277 PF11681.3 KZN92746.1 - 0.001 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) Epimerase PF01370.16 KZN92746.1 - 0.007 15.8 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN92746.1 - 0.043 12.5 0.1 0.063 11.9 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cutinase PF01083.17 KZN92747.1 - 7.9e-55 185.3 0.7 9.1e-55 185.1 0.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KZN92747.1 - 0.00028 20.3 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KZN92747.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 KZN92747.1 - 0.062 12.6 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 KZN92747.1 - 0.073 12.5 0.0 0.098 12.0 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.14 KZN92748.1 - 7.3e-92 308.1 0.0 1e-91 307.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KZN92748.1 - 1.9e-60 203.3 0.0 3.7e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KZN92748.1 - 6.8e-05 22.0 0.0 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KZN92748.1 - 0.00012 22.0 0.1 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN92748.1 - 0.0003 19.4 0.1 0.0012 17.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN92748.1 - 0.00055 18.8 0.1 0.00093 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KZN92748.1 - 0.0006 18.7 0.0 0.00093 18.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KZN92748.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KZN92748.1 - 0.0063 15.4 0.1 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KZN92748.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN92748.1 - 0.011 15.6 0.0 0.044 13.8 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 KZN92748.1 - 0.052 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.1 KZN92748.1 - 0.083 12.9 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KZN92748.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KZN92748.1 - 0.17 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AMP-binding PF00501.23 KZN92749.1 - 2.7e-79 266.4 0.0 3.3e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN92749.1 - 5.1e-13 49.7 0.3 1.3e-12 48.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 KZN92750.1 - 1.4e-51 174.0 0.6 7.8e-51 171.6 0.4 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KZN92750.1 - 4.4e-16 59.4 0.1 2.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KZN92750.1 - 0.00044 19.5 0.1 0.0034 16.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 KZN92750.1 - 0.01 15.1 0.2 0.17 11.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KZN92750.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KZN92750.1 - 0.024 13.8 0.1 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 KZN92750.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KZN92750.1 - 0.081 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 KZN92750.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1749 PF08538.5 KZN92751.1 - 8.3e-94 313.8 0.0 1e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KZN92751.1 - 9.3e-09 35.4 0.2 1.4e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN92751.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AA_permease PF00324.16 KZN92752.1 - 3.7e-104 348.7 35.4 4.2e-104 348.5 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN92752.1 - 4.9e-30 104.4 39.8 6.2e-30 104.0 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.7 KZN92752.1 - 0.41 10.7 3.2 9.2 6.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) HAD_2 PF13419.1 KZN92753.1 - 6.6e-24 85.0 0.2 1.4e-23 84.0 0.2 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KZN92753.1 - 3.8e-06 26.5 0.0 7.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KZN92753.1 - 0.00072 20.0 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mcp5_PH PF12814.2 KZN92754.1 - 2.2e-46 156.7 0.0 4.8e-46 155.6 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KZN92754.1 - 0.0023 17.7 12.3 0.013 15.2 3.7 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein GldM_N PF12081.3 KZN92754.1 - 0.053 13.0 1.1 0.083 12.4 0.8 1.2 1 0 0 1 1 1 0 GldM N-terminal domain IncA PF04156.9 KZN92754.1 - 0.058 12.9 8.6 0.14 11.7 6.0 1.6 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 KZN92754.1 - 0.23 10.0 7.8 0.37 9.3 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 KZN92754.1 - 0.25 10.5 11.8 0.42 9.7 0.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 KZN92754.1 - 0.3 11.2 0.7 2.5 8.2 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF212 PF02681.9 KZN92754.1 - 1.8 8.2 3.8 0.94 9.1 0.8 1.8 2 0 0 2 2 2 0 Divergent PAP2 family V_ATPase_I PF01496.14 KZN92754.1 - 2.9 5.6 1.4 4.6 4.9 1.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KZN92754.1 - 5.2 6.0 8.6 8.5 5.3 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cyt-b5 PF00173.23 KZN92755.1 - 4e-20 71.3 0.0 4.5e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 KZN92755.1 - 0.029 14.2 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H BRX PF08381.6 KZN92755.1 - 0.098 11.7 0.2 0.51 9.4 0.2 2.0 2 1 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 OB_NTP_bind PF07717.11 KZN92756.1 - 3.1e-29 101.0 0.0 8.3e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KZN92756.1 - 8.1e-26 90.0 0.0 4.3e-25 87.6 0.0 2.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN92756.1 - 3.2e-12 46.1 0.0 7.3e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN92756.1 - 1.2e-06 28.1 0.2 6e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 KZN92756.1 - 2.5e-05 23.3 0.0 5.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KZN92756.1 - 5.7e-05 23.2 0.1 0.00023 21.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KZN92756.1 - 0.0035 17.3 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 KZN92756.1 - 0.013 15.2 0.1 0.062 13.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KZN92756.1 - 0.014 14.9 0.0 0.014 14.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain SRP54 PF00448.17 KZN92756.1 - 0.058 12.8 0.2 0.14 11.5 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 KZN92756.1 - 0.079 12.4 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KZN92756.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.5 1 1 1 2 2 1 0 AAA domain Pkinase PF00069.20 KZN92757.1 - 1.2e-40 139.2 0.0 2.4e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92757.1 - 1.6e-23 83.0 0.0 3.5e-23 81.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92757.1 - 0.022 13.7 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KZN92757.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KZN92757.1 - 0.35 9.6 0.0 0.49 9.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 KZN92758.1 - 7.5e-210 696.5 0.0 5.2e-90 301.8 0.0 3.9 3 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KZN92758.1 - 8.8e-199 658.5 8.2 6e-38 130.3 0.1 6.5 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 KZN92758.1 - 1.4e-55 185.4 12.8 2.4e-11 43.7 0.1 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KZN92758.1 - 2.5e-17 63.5 1.4 1.6e-06 28.9 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 KZN92758.1 - 3e-06 27.0 0.4 0.5 9.8 0.0 4.3 4 0 0 4 4 4 3 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 KZN92758.1 - 0.007 14.9 0.1 26 3.1 0.0 4.6 5 0 0 5 5 5 0 Alcohol acetyltransferase Imm1 PF14430.1 KZN92758.1 - 0.097 12.8 0.0 0.71 10.0 0.0 2.5 3 0 0 3 3 3 0 Immunity protein Imm1 K_oxygenase PF13434.1 KZN92759.1 - 2.4e-109 365.3 0.0 6.6e-109 363.9 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KZN92759.1 - 3.4e-12 46.8 0.0 5.1e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN92759.1 - 1.7e-05 24.8 0.0 0.00076 19.4 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN92759.1 - 2.2e-05 24.3 0.1 0.0029 17.4 0.0 3.2 2 2 0 2 2 2 1 FAD-NAD(P)-binding Ank_2 PF12796.2 KZN92760.1 - 2.1e-49 165.7 1.4 5.1e-17 61.9 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 KZN92760.1 - 2.1e-38 131.4 7.5 2.1e-38 131.4 5.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 KZN92760.1 - 2.8e-33 112.0 3.4 1.7e-09 37.0 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KZN92760.1 - 1.4e-28 98.2 4.6 2.1e-08 34.1 0.0 5.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN92760.1 - 2.3e-23 79.9 3.1 1.1e-07 31.3 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KZN92760.1 - 4.5e-23 81.1 7.9 1.1e-08 35.3 0.2 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) HAUS-augmin3 PF14932.1 KZN92762.1 - 7.5 5.6 19.3 0.02 14.0 1.8 2.9 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 Cyclin PF08613.6 KZN92763.1 - 2.1e-32 112.5 0.0 2.2e-32 112.5 0.0 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN92763.1 - 0.00048 19.6 0.1 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Na_Ca_ex PF01699.19 KZN92764.1 - 3.1e-22 78.6 23.6 3.9e-13 49.1 3.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF202 PF02656.10 KZN92764.1 - 0.011 15.9 8.1 4.7 7.4 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) PALP PF00291.20 KZN92765.1 - 1.1e-57 195.6 0.0 1.4e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KZN92765.1 - 5.6e-07 29.2 0.0 7.2e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 KZN92766.1 - 9e-24 83.6 4.3 3.3e-22 78.5 3.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KZN92766.1 - 5.5e-05 23.2 0.5 0.0002 21.3 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 KZN92766.1 - 0.00012 21.3 0.1 0.0021 17.3 0.0 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 KZN92766.1 - 0.0046 16.5 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KZN92766.1 - 0.0068 15.9 1.0 0.023 14.2 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KZN92766.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 KZN92766.1 - 0.05 13.0 0.1 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 KZN92766.1 - 0.059 13.6 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KZN92766.1 - 0.067 12.3 0.3 0.2 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN92766.1 - 0.067 13.3 0.5 0.17 12.0 0.4 1.9 1 1 0 1 1 1 0 AAA domain FBP PF07299.6 KZN92766.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) AAA PF00004.24 KZN92766.1 - 0.31 11.2 1.4 1.1 9.4 1.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GPI-anchored PF10342.4 KZN92767.1 - 9.8e-06 25.9 0.2 3.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 KZN92767.1 - 5.3e-05 23.5 8.3 5.3e-05 23.5 5.7 1.8 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 KZN92768.1 - 7.6e-38 130.4 0.5 1.2e-37 129.7 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KZN92768.1 - 9.1e-16 57.3 0.1 1e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 KZN92769.1 - 1.2e-72 242.9 2.7 1.4e-72 242.7 1.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family ECR1_N PF14382.1 KZN92769.1 - 0.029 13.6 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region E6 PF00518.12 KZN92769.1 - 0.1 12.9 2.2 1.7 8.9 0.1 2.4 2 1 0 2 2 2 0 Early Protein (E6) Pkinase PF00069.20 KZN92770.1 - 4.7e-71 238.9 0.0 1.4e-70 237.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92770.1 - 1.4e-44 152.1 0.0 1.9e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN92770.1 - 1.1e-07 31.0 0.0 3.5e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN92770.1 - 3.7e-05 22.8 0.1 6.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KZN92770.1 - 0.019 14.2 0.1 0.05 12.9 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KZN92770.1 - 0.05 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 KZN92771.1 - 3.9e-78 260.8 0.0 4.6e-78 260.6 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.7 KZN92772.1 - 7.4e-38 129.5 0.1 3.8e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.15 KZN92773.1 - 2e-73 247.7 0.0 2.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KZN92773.1 - 3.5e-43 146.6 0.0 2.2e-42 144.0 0.0 2.1 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KZN92773.1 - 8e-18 64.7 0.1 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KZN92773.1 - 0.014 15.3 2.4 0.45 10.4 1.5 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase MIT PF04212.13 KZN92774.1 - 1.8e-09 37.3 0.2 5.1e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pou PF00157.12 KZN92774.1 - 0.14 11.7 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Zn_clus PF00172.13 KZN92775.1 - 4.5e-09 36.0 7.2 4.5e-09 36.0 5.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN92775.1 - 7.6e-05 21.7 0.1 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBP1_TM PF14812.1 KZN92775.1 - 9 6.6 6.6 0.61 10.4 0.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M24 PF00557.19 KZN92776.1 - 2e-51 174.5 0.4 2.7e-51 174.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KZN92776.1 - 2.4e-24 85.2 0.0 4.8e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BTB PF00651.26 KZN92777.1 - 0.0061 16.5 0.0 0.029 14.3 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_M22 PF00814.20 KZN92777.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family MBOAT PF03062.14 KZN92778.1 - 1.4e-36 126.2 16.9 1.4e-36 126.2 11.7 3.1 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KZN92778.1 - 1.4e-05 25.0 2.8 3.3e-05 23.8 1.9 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family UPF0093 PF03653.8 KZN92778.1 - 0.99 9.3 14.0 0.47 10.4 6.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) DLH PF01738.13 KZN92779.1 - 5.5e-18 65.0 0.0 5.7e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KZN92779.1 - 5.7e-06 26.1 0.0 7.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN92779.1 - 0.042 13.7 0.0 0.84 9.4 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family HHH_5 PF14520.1 KZN92779.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain CH PF00307.26 KZN92780.1 - 1.9e-64 214.4 0.0 1.7e-20 73.0 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KZN92780.1 - 1.2e-05 25.3 0.6 0.00068 19.7 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 KZN92780.1 - 8.6e-05 22.1 0.0 0.51 10.0 0.0 3.7 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_1 PF00036.27 KZN92780.1 - 0.078 12.3 0.6 13 5.3 0.1 3.3 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 KZN92780.1 - 0.13 12.2 2.9 2.1 8.4 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain DDHD PF02862.12 KZN92781.1 - 1.2e-51 175.7 4.0 1.4e-49 168.9 0.0 2.6 3 0 0 3 3 3 2 DDHD domain PGAP1 PF07819.8 KZN92781.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein PXA PF02194.10 KZN92782.1 - 9.7e-39 132.8 0.0 2.6e-38 131.4 0.0 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KZN92782.1 - 4.9e-23 81.3 0.0 1.4e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KZN92782.1 - 1.9e-10 40.4 0.3 5.4e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 PX domain PC4 PF02229.11 KZN92783.1 - 2.2e-20 71.5 0.1 4.1e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 KZN92784.1 - 3.8e-203 675.4 0.0 5.3e-203 675.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KZN92784.1 - 2.7e-93 312.2 0.2 4.3e-93 311.5 0.2 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KZN92784.1 - 2.8e-54 183.2 0.7 1.5e-52 177.6 0.0 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.17 KZN92785.1 - 1.4e-11 43.8 0.0 1.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN92785.1 - 8.1e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN92785.1 - 4.2e-07 29.7 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KZN92785.1 - 0.0031 17.2 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1510 PF07423.6 KZN92785.1 - 5.1 6.3 6.2 7.3 5.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mito_carr PF00153.22 KZN92786.1 - 3.1e-76 251.1 1.5 2e-25 88.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 KZN92787.1 - 9.5e-24 84.2 0.1 1.7e-23 83.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 KZN92788.1 - 3e-13 48.9 9.3 6.3e-12 44.5 4.2 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FA_hydroxylase PF04116.8 KZN92790.1 - 1.4e-15 57.6 18.5 1.4e-15 57.6 12.8 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily NCA2 PF08637.5 KZN92791.1 - 1.9e-80 269.8 0.0 3.1e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 KZN92792.1 - 1.8e-65 219.2 0.0 2.2e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN92792.1 - 7.5e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KZN92792.1 - 5.8e-14 51.7 0.0 7.5e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN92792.1 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN92792.1 - 2.4e-06 26.8 0.0 2.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN92792.1 - 0.0058 16.5 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN92792.1 - 0.022 14.0 0.0 0.1 11.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 KZN92792.1 - 0.033 13.3 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KZN92792.1 - 0.048 12.8 0.0 0.19 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KZN92792.1 - 0.1 12.1 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KZN92792.1 - 0.12 12.6 0.0 6.1 7.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KZN92792.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 KZN92793.1 - 1.9e-65 219.0 0.0 1.5e-41 141.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN92793.1 - 4e-13 49.7 0.5 0.00035 20.6 0.0 4.1 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 KZN92793.1 - 3e-09 36.7 0.5 0.0043 16.7 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN92793.1 - 5.2e-08 33.1 4.6 0.047 13.8 0.2 4.8 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.1 KZN92793.1 - 4.6e-07 29.7 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KZN92793.1 - 9.4e-07 28.6 0.0 4.8e-05 23.1 0.0 2.9 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_17 PF13207.1 KZN92793.1 - 9.4e-06 26.4 0.0 0.13 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN92793.1 - 1.4e-05 25.1 0.1 0.066 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KZN92793.1 - 1.9e-05 24.1 0.0 0.036 13.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KZN92793.1 - 2.3e-05 23.8 3.9 1.7 7.9 0.0 4.2 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 KZN92793.1 - 3e-05 23.2 0.0 0.017 14.1 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 KZN92793.1 - 3.3e-05 23.6 0.3 0.024 14.3 0.1 3.0 2 2 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 KZN92793.1 - 4.4e-05 22.3 0.1 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 KZN92793.1 - 5.9e-05 22.1 0.0 0.095 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.9 KZN92793.1 - 9.2e-05 22.4 0.0 0.014 15.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KZN92793.1 - 0.00023 21.3 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 KZN92793.1 - 0.00031 20.4 0.1 0.41 10.4 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain Rad17 PF03215.10 KZN92793.1 - 0.00039 19.2 0.1 0.0037 15.9 0.0 2.3 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KZN92793.1 - 0.00059 19.4 1.0 0.053 13.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN92793.1 - 0.0051 16.4 2.9 1.3 8.6 1.2 3.7 2 2 1 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 KZN92793.1 - 0.0051 16.8 0.0 0.54 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 KZN92793.1 - 0.0073 16.5 0.2 0.99 9.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 KZN92793.1 - 0.008 15.2 0.0 0.99 8.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KZN92793.1 - 0.0083 16.0 0.2 1.4 8.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KZN92793.1 - 0.012 15.1 0.0 1.7 8.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KZN92793.1 - 0.018 14.2 0.1 3.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Miro PF08477.8 KZN92793.1 - 0.034 14.6 0.1 0.21 12.0 0.0 2.4 2 0 0 2 2 1 0 Miro-like protein AAA_30 PF13604.1 KZN92793.1 - 0.038 13.5 1.0 0.69 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.5 KZN92793.1 - 0.041 13.0 0.1 0.86 8.7 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 KZN92793.1 - 0.043 14.1 0.1 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KZN92793.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KZN92794.1 - 1.3e-13 50.3 0.0 2.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN92794.1 - 4.6e-10 39.3 0.0 8.6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN92794.1 - 7.4e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN92794.1 - 0.0034 17.2 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif PI3_PI4_kinase PF00454.22 KZN92795.1 - 1.5e-50 171.8 0.5 5.7e-50 169.9 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KZN92795.1 - 1.6e-44 152.3 4.1 1.6e-44 152.3 2.9 2.5 3 0 0 3 3 3 1 FAT domain UME PF08064.8 KZN92795.1 - 2.9e-40 136.5 0.4 1.2e-39 134.5 0.3 2.2 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KZN92795.1 - 9.2e-14 50.5 0.0 2.5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 KZN92795.1 - 1.1e-05 24.9 2.4 0.55 9.9 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 KZN92795.1 - 0.00025 21.3 4.0 9.4 7.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN92795.1 - 0.00051 20.6 0.5 2 9.2 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN92795.1 - 0.0087 16.3 1.1 0.43 10.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KZN92795.1 - 0.011 15.4 0.9 25 4.9 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KZN92795.1 - 0.13 12.5 1.3 5 7.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 KZN92796.1 - 2.1e-25 88.3 0.1 2.9e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 KZN92796.1 - 0.0048 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.1 KZN92796.1 - 0.027 14.3 1.4 0.18 11.6 1.0 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase NADH-u_ox-rdase PF10785.4 KZN92797.1 - 2.3e-34 117.4 0.1 3.4e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KZN92797.1 - 5.6e-34 115.7 0.3 8.2e-34 115.2 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 KZN92798.1 - 9.2e-32 108.5 0.3 1.6e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 KZN92799.1 - 1.2e-55 185.4 7.6 8.6e-12 45.0 0.0 8.1 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KZN92799.1 - 1.7e-28 97.5 40.4 7.9e-07 28.5 1.8 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF966 PF06136.8 KZN92799.1 - 3.7 6.8 16.6 5.9 6.2 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RibD_C PF01872.12 KZN92800.1 - 2e-30 105.8 0.0 3e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.9 KZN92801.1 - 3.5e-203 676.1 0.0 4.3e-203 675.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KZN92801.1 - 1.6 8.9 53.2 0.38 10.9 28.7 2.4 2 0 0 2 2 2 0 Nucleoporin FG repeat region COX16 PF14138.1 KZN92802.1 - 7.8e-30 102.8 0.1 1e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.22 KZN92803.1 - 1.7e-60 204.2 0.0 2.1e-59 200.6 0.0 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KZN92803.1 - 9.5e-08 32.3 0.0 4.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 KZN92803.1 - 0.0031 17.1 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KZN92803.1 - 0.0032 17.7 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family F-box PF00646.28 KZN92804.1 - 0.0013 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KZN92804.1 - 0.051 13.3 0.9 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 KZN92804.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain FGGY_C PF02782.11 KZN92806.1 - 2.2e-49 167.7 0.3 3.3e-49 167.2 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KZN92806.1 - 1.6e-24 86.6 0.1 1.3e-21 77.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KZN92806.1 - 0.051 12.8 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Na_Ca_ex PF01699.19 KZN92807.1 - 3.8e-30 104.3 22.2 1e-17 64.0 5.9 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KZN92807.1 - 6.3e-14 52.1 10.5 6.3e-14 52.1 7.3 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF307) AAA PF00004.24 KZN92808.1 - 6e-43 146.2 0.0 9.9e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN92808.1 - 1.1e-07 31.7 0.0 2.8e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN92808.1 - 3.6e-07 30.2 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KZN92808.1 - 7.1e-06 26.1 0.1 3.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN92808.1 - 1.1e-05 25.5 0.1 0.00069 19.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN92808.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KZN92808.1 - 0.00022 22.0 0.0 0.00052 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KZN92808.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KZN92808.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KZN92808.1 - 0.0032 17.3 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN92808.1 - 0.0034 16.5 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KZN92808.1 - 0.0046 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KZN92808.1 - 0.0052 15.5 0.0 0.0095 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 KZN92808.1 - 0.0057 15.7 0.0 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 KZN92808.1 - 0.0068 16.7 0.0 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KZN92808.1 - 0.01 14.9 0.1 0.026 13.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KZN92808.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KZN92808.1 - 0.014 15.0 0.0 0.038 13.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KZN92808.1 - 0.019 14.2 0.0 0.064 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 KZN92808.1 - 0.028 13.8 0.1 0.13 11.6 0.0 1.8 1 1 0 2 2 2 0 AAA domain DUF2072 PF09845.4 KZN92808.1 - 0.031 14.1 0.1 0.076 12.9 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF815 PF05673.8 KZN92808.1 - 0.04 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KZN92808.1 - 0.044 13.2 0.0 0.21 11.0 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KZN92808.1 - 0.051 13.7 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 KZN92808.1 - 0.051 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Histone PF00125.19 KZN92808.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 UFD1 PF03152.9 KZN92810.1 - 1.6e-22 79.4 0.0 1.3e-18 66.7 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBA PF00627.26 KZN92810.1 - 0.064 13.1 0.6 0.37 10.6 0.3 2.4 2 0 0 2 2 2 0 UBA/TS-N domain zinc_ribbon_5 PF13719.1 KZN92810.1 - 6.6 6.4 11.7 8.4 6.0 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Yip1 PF04893.12 KZN92811.1 - 4.6e-07 29.5 16.9 8.4e-06 25.3 6.1 2.4 2 1 0 2 2 2 2 Yip1 domain Bac_surface_Ag PF01103.18 KZN92812.1 - 5.9e-39 134.4 0.8 7.4e-39 134.0 0.6 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 KZN92813.1 - 5e-25 87.5 0.1 7.1e-25 87.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans_2 PF11951.3 KZN92814.1 - 3.2e-14 52.3 0.3 4.7e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 KZN92815.1 - 1.1e-78 264.4 0.1 1.3e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 KZN92816.1 - 1.6e-23 82.9 0.0 7.2e-14 51.7 0.0 2.7 1 1 1 2 2 2 2 ABC1 family RIO1 PF01163.17 KZN92816.1 - 0.024 13.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KZN92816.1 - 0.061 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family KAP PF05804.7 KZN92818.1 - 0.0066 14.4 0.0 0.077 10.9 0.0 2.2 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Arm PF00514.18 KZN92818.1 - 0.11 12.3 0.7 28 4.7 0.2 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DPM3 PF08285.6 KZN92819.1 - 1.2e-28 98.8 0.4 1.3e-28 98.7 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1469 PF07332.6 KZN92819.1 - 4.5 7.0 8.2 1.9 8.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Pribosyltran PF00156.22 KZN92820.1 - 8.4e-09 35.2 0.1 2.8e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Acyl-CoA_dh_2 PF08028.6 KZN92821.1 - 1.2e-15 57.8 0.2 1.2e-15 57.8 0.2 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN92821.1 - 1.5e-07 31.9 0.1 2.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KZN92821.1 - 0.00035 20.6 0.9 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN92821.1 - 0.084 12.4 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain EAP30 PF04157.11 KZN92822.1 - 3.8e-58 196.2 0.0 4.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 KZN92822.1 - 0.015 14.9 0.3 0.084 12.5 0.0 2.4 4 0 0 4 4 4 0 MarR family HTH_6 PF01418.12 KZN92822.1 - 0.065 12.9 0.0 0.41 10.4 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Ribosomal_L30_N PF08079.7 KZN92823.1 - 2.7e-24 84.9 13.6 4.6e-24 84.2 9.4 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KZN92823.1 - 3.6e-17 61.6 2.9 4.4e-17 61.4 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PRK PF00485.13 KZN92824.1 - 0.0037 16.8 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KZN92824.1 - 0.0065 17.2 0.2 0.38 11.5 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN92824.1 - 0.02 15.1 0.0 0.088 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KZN92824.1 - 0.025 13.6 0.0 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.9 KZN92824.1 - 0.039 12.9 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 KZN92824.1 - 0.06 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 KZN92824.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KZN92824.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain adh_short PF00106.20 KZN92825.1 - 1.1e-59 201.0 8.9 8.5e-30 103.8 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KZN92825.1 - 1.4e-31 108.4 0.0 2.9e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KZN92825.1 - 2.5e-27 95.7 2.8 9.2e-13 48.2 0.1 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 KZN92825.1 - 0.0013 18.2 3.2 0.75 9.1 0.0 2.8 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KZN92825.1 - 0.0025 16.9 0.2 0.0025 16.9 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 KZN92825.1 - 0.015 15.1 0.9 2.1 8.1 0.7 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain IBR PF01485.16 KZN92826.1 - 0.00017 21.3 5.4 0.00017 21.3 3.8 4.6 4 1 0 4 4 4 3 IBR domain MFS_1 PF07690.11 KZN92828.1 - 2.7e-41 141.4 41.0 2.7e-41 141.4 28.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN92828.1 - 6.9e-18 64.1 24.4 8.9e-18 63.8 16.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN92828.1 - 1e-14 54.0 8.0 1e-14 54.0 5.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter PALP PF00291.20 KZN92829.1 - 1.3e-27 96.8 0.0 2.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 KZN92829.1 - 1.4e-09 38.2 0.0 4.3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Ferric_reduct PF01794.14 KZN92830.1 - 1.6e-17 63.7 14.2 1.6e-17 63.7 9.9 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN92830.1 - 1.2e-16 60.4 0.0 3e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KZN92830.1 - 2.6e-10 40.4 0.0 3.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KZN92830.1 - 0.0038 17.3 10.2 0.11 12.6 1.9 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) Cys_Met_Meta_PP PF01053.15 KZN92832.1 - 7.8e-139 462.2 0.0 9.1e-139 462.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 KZN92832.1 - 6e-05 21.5 0.0 0.0003 19.1 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 KZN92832.1 - 0.00082 18.5 0.0 0.0022 17.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KZN92832.1 - 0.002 17.3 0.0 0.0048 16.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 KZN92832.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Na_H_Exchanger PF00999.16 KZN92833.1 - 1.2e-33 116.2 36.0 9e-26 90.2 17.5 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Fungal_trans PF04082.13 KZN92835.1 - 2.3e-33 115.1 0.0 1.8e-31 108.9 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92835.1 - 1.3e-07 31.3 8.8 2.2e-07 30.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.9 KZN92836.1 - 7.1e-172 572.0 31.1 9.9e-172 571.5 21.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KZN92836.1 - 2.8e-11 43.3 0.1 5e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KZN92836.1 - 7.2e-10 38.5 0.2 2.6e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KZN92836.1 - 0.0046 16.3 0.1 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Mur_ligase PF01225.20 KZN92836.1 - 0.035 14.1 0.0 7 6.8 0.0 2.7 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Csm1 PF12539.3 KZN92837.1 - 1.2e-26 92.9 0.1 2.5e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 AAA_13 PF13166.1 KZN92837.1 - 0.0063 15.0 3.5 0.011 14.2 2.4 1.3 1 0 0 1 1 1 1 AAA domain DUF2968 PF11180.3 KZN92837.1 - 0.0084 15.5 12.0 0.0084 15.5 8.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Vps5 PF09325.5 KZN92837.1 - 0.022 14.0 4.7 0.067 12.4 3.3 1.7 1 1 0 1 1 1 0 Vps5 C terminal like APG6 PF04111.7 KZN92837.1 - 0.028 13.4 9.2 0.055 12.5 6.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3138 PF11336.3 KZN92837.1 - 0.083 11.0 5.9 0.15 10.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Baculo_PEP_C PF04513.7 KZN92837.1 - 0.95 9.2 7.7 0.94 9.3 3.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KZN92837.1 - 1.3 8.5 13.2 17 4.9 5.1 2.8 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 KZN92837.1 - 1.8 7.1 10.8 3.3 6.2 7.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KZN92837.1 - 1.9 7.6 4.2 1.8 7.6 1.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 KZN92837.1 - 2.5 7.2 13.7 2.3 7.3 5.8 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Bap31 PF05529.7 KZN92837.1 - 3.7 6.9 11.1 22 4.4 5.6 2.7 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF2203 PF09969.4 KZN92837.1 - 3.8 7.7 6.1 13 6.0 0.9 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) COG2 PF06148.6 KZN92837.1 - 5.3 6.9 8.4 6.5 6.6 3.4 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 KZN92837.1 - 6.7 6.6 14.0 15 5.4 8.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding AAA PF00004.24 KZN92838.1 - 3e-37 127.7 0.0 6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KZN92838.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN92838.1 - 1.2e-05 26.1 0.0 3.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KZN92838.1 - 2.3e-05 24.5 0.1 0.00067 19.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN92838.1 - 4.5e-05 23.5 0.3 0.0012 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KZN92838.1 - 5.4e-05 22.3 0.0 9.5e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN92838.1 - 8.2e-05 22.3 0.2 0.00078 19.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN92838.1 - 9.7e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KZN92838.1 - 0.00026 20.9 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KZN92838.1 - 0.0004 19.8 0.8 0.032 13.6 0.2 2.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KZN92838.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KZN92838.1 - 0.00067 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KZN92838.1 - 0.001 19.2 0.0 0.0028 17.7 0.0 1.9 1 1 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 KZN92838.1 - 0.0012 18.9 0.0 0.004 17.2 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 KZN92838.1 - 0.0026 17.7 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN92838.1 - 0.0027 18.0 0.2 0.01 16.1 0.0 2.1 3 0 0 3 3 1 1 AAA domain NACHT PF05729.7 KZN92838.1 - 0.0036 16.9 0.0 0.0097 15.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 KZN92838.1 - 0.0058 16.2 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KZN92838.1 - 0.0071 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KZN92838.1 - 0.012 15.3 0.4 0.054 13.2 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 KZN92838.1 - 0.029 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KZN92838.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 KZN92838.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 KZN92838.1 - 0.04 14.2 0.2 0.1 12.9 0.0 1.9 2 1 0 2 2 1 0 ABC transporter DUF815 PF05673.8 KZN92838.1 - 0.057 12.3 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KZN92838.1 - 0.058 13.0 0.0 0.2 11.3 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase KaiC PF06745.8 KZN92838.1 - 0.1 11.7 0.0 0.49 9.4 0.0 2.0 1 1 1 2 2 2 0 KaiC SKI PF01202.17 KZN92838.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase UPF0079 PF02367.12 KZN92838.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 KZN92838.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KZN92838.1 - 0.15 10.8 0.0 0.48 9.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Guanylate_kin PF00625.16 KZN92838.1 - 0.15 11.4 0.0 0.95 8.8 0.0 2.2 2 1 0 3 3 3 0 Guanylate kinase COesterase PF00135.23 KZN92840.1 - 4.9e-91 306.0 0.1 2e-90 304.0 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN92840.1 - 3.3e-06 26.8 0.0 2e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN92840.1 - 0.00054 19.2 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FKBP_C PF00254.23 KZN92841.1 - 1.1e-23 82.9 0.0 1.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 KZN92842.1 - 3.9e-13 49.5 0.0 9.9e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 PHP domain ACPS PF01648.15 KZN92843.1 - 3.1e-16 59.2 0.0 4.3e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2611 PF11022.3 KZN92844.1 - 4.4e-29 100.3 0.2 5.1e-29 100.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 KZN92845.1 - 8.7e-66 220.4 0.1 1.2e-65 219.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DIT1_PvcA PF05141.7 KZN92846.1 - 1.3e-65 221.4 0.0 1.7e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MFS_1 PF07690.11 KZN92847.1 - 1e-24 86.9 36.6 1e-24 86.9 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Caleosin PF05042.8 KZN92847.1 - 0.16 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Caleosin related protein DIT1_PvcA PF05141.7 KZN92848.1 - 7.9e-76 255.0 0.0 1e-75 254.6 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Ribonuc_L-PSP PF01042.16 KZN92850.1 - 1.2e-37 128.3 0.0 1.6e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP EAP30 PF04157.11 KZN92852.1 - 3.7e-53 179.9 0.0 5e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KZN92852.1 - 3.8e-27 93.9 0.0 6.9e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KZN92852.1 - 8.4e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 KZN92852.1 - 0.00014 20.9 11.3 0.00086 18.3 0.6 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KZN92852.1 - 0.00045 19.7 6.6 0.00095 18.6 0.7 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GCC2_GCC3 PF07699.8 KZN92852.1 - 0.39 10.3 3.3 1.5 8.4 0.1 2.4 2 0 0 2 2 2 0 GCC2 and GCC3 DZR PF12773.2 KZN92852.1 - 0.74 9.6 5.9 0.2 11.4 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 KZN92853.1 - 3.4e-66 222.6 0.1 4.6e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KZN92853.1 - 0.00025 20.8 0.1 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 KZN92854.1 - 1.2e-25 88.5 0.0 2.1e-11 43.0 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KZN92854.1 - 8.3e-16 57.3 0.1 1.9e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KZN92854.1 - 2.9e-14 52.8 0.0 6.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 KZN92854.1 - 1.5e-09 37.1 0.0 1.8e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KZN92854.1 - 6.2e-07 28.9 0.7 1.3e-06 27.9 0.5 1.5 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 KZN92855.1 - 4.7e-95 318.4 0.0 1.1e-89 300.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KZN92855.1 - 0.0014 18.6 0.1 0.26 11.2 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.13 KZN92855.1 - 0.0032 17.1 0.8 0.57 9.7 0.1 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.1 KZN92855.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KZN92855.1 - 0.0094 16.1 0.0 0.041 14.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KZN92855.1 - 0.012 15.8 0.0 0.078 13.1 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Catalase PF00199.14 KZN92856.1 - 5.5e-155 515.7 0.2 6.8e-155 515.4 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN92856.1 - 2.1e-19 69.1 0.0 6.6e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF4066 PF13278.1 KZN92856.1 - 0.0032 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KZN92856.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Cation_efflux PF01545.16 KZN92857.1 - 3.1e-60 203.6 2.9 3.9e-60 203.3 2.0 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KZN92857.1 - 0.00018 20.6 8.7 0.00027 20.0 6.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter BPD_transp_2 PF02653.11 KZN92857.1 - 0.02 13.8 1.4 0.02 13.8 1.0 1.6 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Amidase PF01425.16 KZN92858.1 - 9.7e-98 327.8 0.0 1.1e-97 327.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.7 KZN92859.1 - 1.9e-10 41.0 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN92859.1 - 8.4e-08 32.1 0.0 2.2e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN92859.1 - 2.4e-06 28.0 0.0 5.7e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN92859.1 - 1.4e-05 25.5 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KZN92859.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KZN92859.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92859.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_3 PF13302.1 KZN92860.1 - 6e-14 52.4 0.0 8.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN92860.1 - 8.4e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KZN92860.1 - 0.00019 21.4 0.1 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KZN92860.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KZN92861.1 - 1.1e-23 83.5 48.3 1.4e-23 83.2 33.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_1 PF01644.12 KZN92862.1 - 2e-85 284.6 0.1 3.6e-85 283.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KZN92862.1 - 2.3e-31 107.2 0.1 4.6e-31 106.3 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KZN92862.1 - 2.8e-22 78.8 0.5 9.4e-20 70.4 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KZN92862.1 - 5.6e-08 32.7 0.2 5.6e-08 32.7 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KZN92862.1 - 4.1e-06 26.7 0.0 8.5e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1774 PF08611.5 KZN92863.1 - 3.1e-36 123.4 2.7 3.1e-36 123.4 1.9 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.20 KZN92864.1 - 4.9e-40 137.5 0.1 8.6e-40 136.7 0.1 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Cupin_3 PF05899.7 KZN92865.1 - 7.6e-06 25.2 0.0 1.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 KZN92865.1 - 5e-05 22.8 0.0 5.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Peptidase_M28 PF04389.12 KZN92866.1 - 5.7e-27 94.6 0.1 9.8e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KZN92866.1 - 8.3e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.1 KZN92867.1 - 3.9e-28 98.0 3.8 9.2e-28 96.8 2.7 1.7 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 KZN92867.1 - 0.003 17.2 0.2 0.0083 15.7 0.1 1.8 1 0 0 1 1 1 1 R3H domain DND1_DSRM PF14709.1 KZN92869.1 - 0.038 14.2 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 MFS_1 PF07690.11 KZN92870.1 - 5.4e-26 91.1 35.0 8.1e-26 90.5 24.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TGT PF01702.13 KZN92871.1 - 2.1e-92 308.7 0.0 2.6e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 KZN92872.1 - 5.7e-110 366.5 0.0 6.5e-110 366.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.11 KZN92873.1 - 2.9e-22 78.2 25.0 4.9e-12 45.5 5.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KZN92873.1 - 0.0032 17.2 6.1 0.0032 17.2 4.2 2.6 2 1 0 2 2 2 1 IBR domain DDE_Tnp_IS66 PF03050.9 KZN92873.1 - 0.043 13.0 0.6 0.057 12.6 0.4 1.3 1 0 0 1 1 1 0 Transposase IS66 family Transp_Tc5_C PF04236.10 KZN92873.1 - 0.054 13.7 15.5 0.44 10.8 2.3 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zinc_ribbon_5 PF13719.1 KZN92873.1 - 0.18 11.4 6.0 2.8 7.6 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KZN92873.1 - 0.99 9.1 8.4 2.4 7.9 0.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KZN92873.1 - 1.6 8.6 6.4 9.1 6.1 0.2 2.8 2 1 0 2 2 2 0 PhnA Zinc-Ribbon DNA_RNApol_7kD PF03604.8 KZN92873.1 - 2.2 7.8 9.7 0.44 10.0 2.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.7 KZN92873.1 - 6.3 6.8 22.4 6.7 6.8 3.5 3.3 2 2 0 2 2 2 0 TFIIH C1-like domain Ada_Zn_binding PF02805.11 KZN92876.1 - 3.5e-28 96.9 2.9 5.4e-28 96.3 2.0 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KZN92876.1 - 5.6e-07 29.1 0.0 9.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KZN92876.1 - 0.0098 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 KZN92876.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.1 KZN92876.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain MFS_1 PF07690.11 KZN92877.1 - 2.1e-32 112.2 36.0 2.6e-32 111.9 24.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN92877.1 - 1e-07 30.9 21.2 4e-06 25.6 0.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KZN92877.1 - 0.02 14.6 0.2 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 MFS_1 like family Aldo_ket_red PF00248.16 KZN92878.1 - 8.5e-71 238.0 0.0 9.6e-71 237.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adaptin_N PF01602.15 KZN92878.1 - 0.048 11.9 0.0 0.078 11.2 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Fungal_trans_2 PF11951.3 KZN92879.1 - 1e-05 24.3 2.6 1.6e-05 23.6 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tfb2 PF03849.9 KZN92880.1 - 7.2e-139 462.4 0.0 1.8e-138 461.1 0.0 1.6 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KZN92880.1 - 2.3e-05 24.1 0.1 0.00017 21.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SinI PF08671.5 KZN92880.1 - 0.0059 16.0 0.0 0.063 12.7 0.0 2.3 2 0 0 2 2 2 1 Anti-repressor SinI AAA_12 PF13087.1 KZN92881.1 - 3.4e-26 91.8 0.0 5.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN92881.1 - 5.4e-23 81.8 0.0 9.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN92881.1 - 3.1e-09 36.4 0.0 1.9e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN92881.1 - 8.9e-07 28.6 0.0 0.0018 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KZN92881.1 - 0.00013 21.9 0.0 0.00041 20.2 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KZN92881.1 - 0.0012 18.4 0.1 0.23 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KZN92881.1 - 0.002 17.5 0.0 0.0063 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN92881.1 - 0.0075 16.4 0.0 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN92881.1 - 0.0093 15.9 0.0 0.034 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 KZN92881.1 - 0.014 14.2 0.4 0.23 10.3 0.0 2.6 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA PF00004.24 KZN92881.1 - 0.016 15.3 0.0 0.056 13.6 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 KZN92881.1 - 0.018 14.3 0.0 0.054 12.7 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KZN92881.1 - 0.02 14.4 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KZN92881.1 - 0.026 14.2 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KZN92881.1 - 0.033 13.1 0.7 0.054 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ring_hydroxyl_B PF00866.13 KZN92881.1 - 0.046 13.4 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Zeta_toxin PF06414.7 KZN92881.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KZN92881.1 - 0.058 14.2 0.0 2.3 9.0 0.0 3.4 3 1 1 4 4 2 0 AAA domain NB-ARC PF00931.17 KZN92881.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 KZN92881.1 - 0.069 12.0 0.0 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Arch_ATPase PF01637.13 KZN92881.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase UvrD_C_2 PF13538.1 KZN92881.1 - 0.13 12.4 0.2 0.39 10.8 0.0 1.9 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain SMC_N PF02463.14 KZN92881.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 KZN92881.1 - 0.26 11.4 0.0 0.76 9.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 KZN92881.1 - 0.31 9.8 0.0 0.52 9.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 efThoc1 PF11957.3 KZN92882.1 - 1.2e-175 584.7 3.4 1.8e-175 584.1 2.4 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor NADH_oxidored PF08040.6 KZN92882.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 MNLL subunit Homeobox PF00046.24 KZN92883.1 - 9.3e-17 60.4 3.9 2.2e-16 59.1 2.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KZN92883.1 - 0.029 14.0 0.2 0.085 12.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF1096 PF06493.6 KZN92884.1 - 4.6 7.2 49.5 0.74 9.8 13.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1096) Adaptin_N PF01602.15 KZN92885.1 - 3.7e-124 414.9 4.5 4.4e-124 414.6 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KZN92885.1 - 2.5e-43 146.6 0.0 5.6e-43 145.4 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KZN92885.1 - 8.2e-19 68.0 0.0 2.1e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Ala_racemase_N PF01168.15 KZN92886.1 - 1.9e-41 142.0 0.0 2.3e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Hist_deacetyl PF00850.14 KZN92888.1 - 1.3e-57 195.4 0.0 1.9e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SLAC1 PF03595.12 KZN92889.1 - 1.1e-75 254.2 46.0 1.3e-75 254.0 31.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ATP-grasp_2 PF08442.5 KZN92890.1 - 1.1e-77 259.9 0.3 2.1e-77 259.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KZN92890.1 - 7.5e-25 87.3 0.3 1.4e-24 86.4 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KZN92890.1 - 4.2e-08 32.6 0.2 1.2e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KZN92890.1 - 0.0023 17.5 1.0 0.11 12.0 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_S11 PF00411.14 KZN92890.1 - 0.0024 18.0 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S11 Peripla_BP_2 PF01497.13 KZN92890.1 - 0.034 13.2 0.1 0.08 12.0 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein F-box PF00646.28 KZN92891.1 - 1.3e-06 27.9 4.1 3.8e-06 26.3 1.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KZN92891.1 - 0.00036 20.2 0.5 0.00075 19.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like HSF_DNA-bind PF00447.12 KZN92892.1 - 4.7e-36 123.0 0.2 7.3e-36 122.4 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.3 KZN92893.1 - 4.2e-48 163.4 8.6 4.2e-48 163.4 6.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.14 KZN92893.1 - 0.0068 16.7 12.2 0.0068 16.7 8.5 3.2 2 1 1 3 3 3 1 60s Acidic ribosomal protein Cpl-7 PF08230.6 KZN92893.1 - 0.095 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain Spore_YtfJ PF09579.5 KZN92893.1 - 0.66 9.8 3.1 0.46 10.3 0.9 1.8 1 1 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) p450 PF00067.17 KZN92894.1 - 1.9e-68 231.1 0.0 2.3e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Imm-NTF2-2 PF15631.1 KZN92894.1 - 0.12 12.4 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 NTF2 fold immunity protein RFC1 PF08519.7 KZN92894.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Alpha-amylase PF00128.19 KZN92895.1 - 4e-16 59.2 0.0 4.9e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain HA2 PF04408.18 KZN92897.1 - 1.7e-11 44.0 0.1 4e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Oxidored-like PF09791.4 KZN92898.1 - 1.4e-25 88.4 3.1 2.6e-25 87.5 2.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Ribosomal_L13e PF01294.13 KZN92900.1 - 7.1e-65 217.8 8.5 1.7e-64 216.5 5.7 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e FAM60A PF15396.1 KZN92900.1 - 0.061 13.0 0.2 0.061 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein Family FAM60A Poty_PP PF08440.5 KZN92900.1 - 0.067 12.2 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Bac_luciferase PF00296.15 KZN92900.1 - 0.15 11.1 8.6 0.2 10.7 2.7 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase DUF4422 PF14393.1 KZN92901.1 - 0.17 11.4 0.3 0.27 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) LRR_4 PF12799.2 KZN92902.1 - 5e-40 134.5 54.7 1.4e-08 34.1 1.1 10.9 3 3 10 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN92902.1 - 7.4e-28 96.0 49.4 3.9e-09 36.1 2.3 8.8 6 1 7 13 13 13 11 Leucine rich repeat LRR_1 PF00560.28 KZN92902.1 - 8e-17 58.6 48.4 0.0045 16.8 0.2 15.9 14 4 3 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 KZN92902.1 - 1.1e-15 54.9 47.6 0.13 12.5 0.3 15.1 16 0 0 16 16 16 6 Leucine rich repeat LRR_6 PF13516.1 KZN92902.1 - 2.1e-09 36.4 39.9 1.8 8.8 0.3 13.7 14 1 1 15 15 15 5 Leucine Rich repeat LRR_9 PF14580.1 KZN92902.1 - 0.14 11.6 14.7 5.2 6.5 0.2 4.6 3 1 2 5 5 5 0 Leucine-rich repeat GCIP PF13324.1 KZN92903.1 - 1.6e-10 40.6 0.4 3.9e-10 39.4 0.1 1.7 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting PEX11 PF05648.9 KZN92903.1 - 0.033 13.4 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Sigma70_ner PF04546.8 KZN92903.1 - 0.15 11.6 4.6 0.058 13.0 0.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.4 KZN92903.1 - 3.5 6.2 10.8 5.5 5.5 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.2 KZN92905.1 - 1.4e-22 80.6 0.0 1.8e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN92905.1 - 5.9e-19 68.5 0.0 2.3e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN92905.1 - 2e-08 34.0 0.0 6.7e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KZN92905.1 - 9.9e-07 27.5 0.0 1.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Ndr family PhoPQ_related PF10142.4 KZN92905.1 - 0.017 13.6 0.0 0.051 12.0 0.0 1.6 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Actin PF00022.14 KZN92906.1 - 8e-105 350.4 0.0 9.2e-105 350.2 0.0 1.0 1 0 0 1 1 1 1 Actin 3HCDH_N PF02737.13 KZN92907.1 - 2.5e-51 173.9 2.0 3.2e-51 173.5 1.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN92907.1 - 2.6e-33 114.2 0.0 7.6e-33 112.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KZN92907.1 - 0.0011 18.7 1.1 0.0017 18.2 0.3 1.7 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KZN92907.1 - 0.0038 16.6 0.2 0.024 14.0 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 KZN92907.1 - 0.0045 16.0 0.2 0.0054 15.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 KZN92907.1 - 0.0087 15.0 0.2 0.0087 15.0 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KZN92907.1 - 0.011 15.7 0.3 0.043 13.7 0.1 2.0 2 1 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KZN92907.1 - 0.014 15.1 0.3 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TfuA PF07812.7 KZN92907.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 TfuA-like protein 2-Hacid_dh_C PF02826.14 KZN92907.1 - 0.053 12.6 0.1 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KZN92907.1 - 0.076 13.0 0.6 0.31 11.0 0.3 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 KZN92908.1 - 7.3e-94 313.9 0.0 1.7e-93 312.6 0.0 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KZN92908.1 - 1.9e-61 208.7 28.6 1.7e-59 202.2 0.7 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region PhzC-PhzF PF02567.11 KZN92909.1 - 1.4e-47 162.2 0.0 1.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF1857 PF08982.6 KZN92910.1 - 3.4e-42 143.5 0.0 3.8e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Lipocalin PF00061.18 KZN92910.1 - 0.057 13.4 0.1 0.08 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family 2OG-FeII_Oxy PF03171.15 KZN92912.1 - 1.3e-12 47.8 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KZN92914.1 - 1.1e-08 35.4 0.3 7.9e-07 29.5 0.2 2.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KZN92914.1 - 0.0006 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KZN92914.1 - 0.0087 15.6 0.3 0.12 12.0 0.1 2.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Med27 PF11571.3 KZN92915.1 - 1.9e-18 66.3 0.0 3.2e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 DUF2924 PF11149.3 KZN92915.1 - 0.041 13.9 0.8 0.09 12.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Oxysterol_BP PF01237.13 KZN92915.1 - 0.21 10.0 2.8 0.3 9.5 1.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Menin PF05053.8 KZN92917.1 - 0.044 11.9 2.2 0.056 11.6 1.5 1.2 1 0 0 1 1 1 0 Menin SNF2_N PF00176.18 KZN92919.1 - 2.5e-71 239.9 0.0 4.1e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN92919.1 - 1.2e-14 53.9 0.0 3.7e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN92919.1 - 0.024 14.1 0.0 0.25 10.8 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Pkinase PF00069.20 KZN92920.1 - 1.4e-50 171.9 0.0 3.2e-50 170.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92920.1 - 3.5e-21 75.4 0.0 7.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN92920.1 - 0.00079 19.2 0.6 0.0014 18.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN92920.1 - 0.0086 15.4 0.4 0.062 12.6 0.0 2.1 1 1 1 2 2 2 1 RIO1 family eIF-3c_N PF05470.7 KZN92921.1 - 6.9e-163 542.9 22.0 6.9e-163 542.9 15.3 2.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KZN92921.1 - 1.6e-12 47.6 1.2 1.2e-11 44.8 0.0 3.1 2 1 1 3 3 3 1 PCI domain Perm-CXXC PF15629.1 KZN92923.1 - 0.14 12.2 2.1 0.24 11.4 1.4 1.4 1 0 0 1 1 1 0 Permuted single zf-CXXC unit NmrA PF05368.8 KZN92924.1 - 1.4e-18 67.0 0.0 2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN92924.1 - 5.9e-12 45.9 0.1 2.2e-11 44.0 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN92924.1 - 1.2e-07 31.4 0.1 4e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KZN92924.1 - 0.0005 19.0 0.0 0.00073 18.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KZN92924.1 - 0.0018 17.2 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KZN92924.1 - 0.0055 16.6 0.0 0.0095 15.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase DUF3842 PF12953.2 KZN92924.1 - 0.0061 16.7 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) Saccharop_dh PF03435.13 KZN92924.1 - 0.034 13.1 0.1 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 KZN92924.1 - 0.045 13.4 0.1 0.087 12.4 0.0 1.5 1 1 0 1 1 1 0 KR domain ApbA PF02558.11 KZN92924.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KZN92924.1 - 0.065 13.4 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AAA_17 PF13207.1 KZN92924.1 - 0.072 13.9 0.1 0.19 12.5 0.0 1.6 2 1 0 2 2 1 0 AAA domain RmlD_sub_bind PF04321.12 KZN92924.1 - 0.13 11.0 0.1 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain LysM PF01476.15 KZN92925.1 - 1.2e-07 31.4 0.3 2e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 LysM domain Zn_clus PF00172.13 KZN92926.1 - 2e-09 37.2 9.8 3e-09 36.6 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HR1 PF02185.11 KZN92926.1 - 0.068 12.9 1.2 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 Hr1 repeat HalX PF08663.5 KZN92926.1 - 0.087 12.8 0.7 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 HalX domain DUF4140 PF13600.1 KZN92926.1 - 0.11 12.9 1.0 0.21 12.0 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CoA_transf_3 PF02515.12 KZN92927.1 - 3.7e-27 94.7 0.1 6.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Alpha-L-AF_C PF06964.7 KZN92928.1 - 3.1e-43 147.5 0.0 5.8e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KZN92928.1 - 0.0031 17.5 1.9 0.0031 17.5 1.3 2.5 2 1 1 3 3 3 1 Carbohydrate binding domain CTP_synth_N PF06418.9 KZN92931.1 - 2.7e-109 364.5 0.1 3.8e-109 364.0 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KZN92931.1 - 4e-46 156.8 0.1 6.2e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KZN92931.1 - 7.6e-09 35.3 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KZN92931.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AdoMet_Synthase PF01941.14 KZN92931.1 - 0.076 11.4 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) GHMP_kinases_N PF00288.21 KZN92932.1 - 2.7e-18 65.7 0.0 5.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KZN92932.1 - 5.8e-07 29.6 0.8 8.9e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KZN92932.1 - 0.0027 16.9 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.16 KZN92933.1 - 1.9e-54 184.7 32.1 2.4e-54 184.4 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 KZN92934.1 - 1.8e-84 283.5 31.0 2.2e-84 283.3 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_US9 PF06072.6 KZN92934.1 - 1 9.2 3.2 39 4.1 0.0 3.9 5 0 0 5 5 5 0 Alphaherpesvirus tegument protein US9 MPC PF03650.8 KZN92935.1 - 1.4e-20 73.4 0.0 1.5e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 KZN92936.1 - 4.1e-15 55.0 0.0 4.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 KZN92937.1 - 2e-23 81.9 0.0 2.8e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KZN92937.1 - 4.8e-19 67.8 0.1 2.1e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Sugar_tr PF00083.19 KZN92938.1 - 1.3e-29 103.1 25.7 2.9e-28 98.6 17.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN92938.1 - 2.2e-28 98.9 35.6 1.2e-23 83.4 9.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PIRT PF15099.1 KZN92938.1 - 0.0092 15.1 2.2 0.012 14.8 0.2 2.0 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family LacY_symp PF01306.14 KZN92938.1 - 0.01 14.3 13.7 0.0031 16.1 6.8 2.0 2 1 0 2 2 2 0 LacY proton/sugar symporter Clathrin PF00637.15 KZN92939.1 - 3.1e-200 655.8 33.9 2.7e-35 121.0 0.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KZN92939.1 - 7.9e-34 113.6 0.3 1.1e-06 28.5 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 KZN92939.1 - 2.3e-28 97.8 1.8 5.1e-28 96.7 0.2 2.6 2 0 0 2 2 2 1 Clathrin-H-link TPR_7 PF13176.1 KZN92939.1 - 0.00023 20.7 2.2 39 4.3 0.0 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KZN92939.1 - 0.0035 17.2 4.6 4.4 7.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Vps39_1 PF10366.4 KZN92939.1 - 0.033 14.2 8.5 7.2 6.6 0.0 5.6 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.12 KZN92939.1 - 0.12 12.4 3.8 6.1 7.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92939.1 - 2.9 8.7 16.4 13 6.7 0.1 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 KZN92940.1 - 3e-78 261.9 0.1 5e-78 261.2 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KZN92940.1 - 7.5e-63 211.5 0.0 1.4e-62 210.6 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KZN92940.1 - 1e-36 125.3 0.0 1.9e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KZN92940.1 - 7.7e-30 103.0 0.0 2.6e-29 101.3 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KZN92940.1 - 1.9e-26 93.2 0.0 4.1e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KZN92940.1 - 1.7e-17 62.8 2.2 1.7e-17 62.8 1.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KZN92940.1 - 3.8e-17 62.6 0.2 9.9e-17 61.2 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN92940.1 - 1.3e-16 60.3 0.0 4.2e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KZN92940.1 - 4.1e-11 42.3 3.7 8.5e-07 28.5 0.1 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KZN92940.1 - 4.7e-08 32.6 0.0 8.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KZN92940.1 - 1.3e-07 31.1 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KZN92940.1 - 3.9e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 1 1 ATP-grasp domain HlyD_3 PF13437.1 KZN92940.1 - 7.3e-05 23.0 0.1 0.022 15.0 0.1 3.4 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 KZN92940.1 - 0.00034 19.8 0.0 0.38 9.8 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 KZN92940.1 - 0.0011 18.4 0.1 0.049 12.9 0.0 2.5 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.6 KZN92940.1 - 0.0012 18.3 0.0 0.0055 16.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 KZN92940.1 - 0.017 14.8 1.7 0.85 9.3 0.1 2.6 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 KZN92940.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 KZN92940.1 - 0.12 12.0 1.9 0.72 9.5 0.2 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein COesterase PF00135.23 KZN92941.1 - 1.3e-53 182.5 0.0 1.8e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN92941.1 - 5.8e-06 26.0 0.0 4.3e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 KZN92943.1 - 6.7e-20 71.0 7.5 1.1e-13 50.5 0.2 2.7 4 0 0 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN92943.1 - 2.7e-05 23.9 1.2 4.7e-05 23.1 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF924 PF06041.6 KZN92944.1 - 2.5e-49 167.5 0.0 3.8e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Sulfatase PF00884.18 KZN92945.1 - 9.3e-20 71.0 0.8 2.9e-19 69.4 0.4 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KZN92945.1 - 6.3e-08 32.3 0.1 1.5e-07 31.1 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KZN92945.1 - 0.0026 16.2 0.0 0.0039 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Dispanin PF04505.7 KZN92945.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein PPTA PF01239.17 KZN92946.1 - 4.4e-39 130.2 19.8 8.4e-08 31.2 0.0 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 KZN92946.1 - 0.026 14.8 0.0 0.084 13.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN92946.1 - 0.055 14.1 0.7 11 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4269 PF14091.1 KZN92946.1 - 0.13 12.2 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) PALP PF00291.20 KZN92947.1 - 4.5e-48 164.0 1.3 4.6e-48 164.0 0.2 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.6 KZN92948.1 - 3.2e-114 381.6 0.0 2e-113 378.9 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KZN92948.1 - 2.5e-22 78.6 0.1 9e-12 43.7 0.0 3.3 1 1 3 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KZN92948.1 - 4.4e-11 42.4 0.1 9.7e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KZN92948.1 - 0.00012 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Peptidase_C28 PF05408.6 KZN92948.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase NTF2 PF02136.15 KZN92949.1 - 4.8e-06 26.9 0.2 9.5e-06 25.9 0.2 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KZN92949.1 - 8.7e-05 22.3 0.0 0.00086 19.1 0.0 1.9 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 DUF1470 PF07336.6 KZN92950.1 - 0.0035 17.6 0.1 0.004 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1470) Ish1 PF10281.4 KZN92950.1 - 0.0052 16.8 0.0 0.0064 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF4129 PF13559.1 KZN92950.1 - 0.085 12.8 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) CBM_25 PF03423.8 KZN92950.1 - 0.099 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PepSY_2 PF13670.1 KZN92950.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Pec_lyase_C PF00544.14 KZN92951.1 - 0.0024 17.3 1.6 0.0041 16.5 1.1 1.4 1 0 0 1 1 1 1 Pectate lyase EF-hand_6 PF13405.1 KZN92951.1 - 0.56 10.2 0.1 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KZN92951.1 - 1.6 8.2 5.0 0.57 9.6 0.1 2.4 2 0 0 2 2 2 0 EF hand Cupin_2 PF07883.6 KZN92953.1 - 8.1e-14 50.8 1.4 1.2e-13 50.3 0.5 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KZN92953.1 - 5.6e-06 25.8 0.1 8.3e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KZN92953.1 - 4.7e-05 23.0 0.0 7.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KZN92953.1 - 0.00048 19.4 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KZN92953.1 - 0.0018 17.9 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.13 KZN92953.1 - 0.0058 16.2 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase GPI PF06560.6 KZN92953.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 KZN92953.1 - 0.025 14.8 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase ARD PF03079.9 KZN92953.1 - 0.044 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family Ribosomal_L38e PF01781.13 KZN92954.1 - 9.2e-33 111.8 2.2 1.1e-32 111.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Pox_A3L PF05288.6 KZN92954.1 - 0.051 13.3 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein LAGLIDADG_WhiA PF14527.1 KZN92954.1 - 0.16 11.8 0.2 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Glyco_hydro_61 PF03443.9 KZN92956.1 - 6.4e-85 284.3 0.1 7.3e-85 284.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_3 PF13302.1 KZN92957.1 - 1.4e-16 60.9 0.0 2.1e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN92957.1 - 0.042 13.5 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.19 KZN92957.1 - 0.15 12.1 0.1 1.9 8.5 0.1 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.11 KZN92958.1 - 2.3e-48 164.2 0.0 5e-48 163.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.10 KZN92959.1 - 8e-72 242.1 2.6 9.3e-72 241.9 1.8 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KZN92959.1 - 5.1e-07 28.8 1.0 1.1e-06 27.8 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KZN92959.1 - 0.0048 15.7 1.9 0.0076 15.1 1.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 KZN92959.1 - 0.11 12.6 0.3 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain Taxilin PF09728.4 KZN92960.1 - 1.6e-96 323.0 53.5 4.2e-65 219.8 18.0 2.6 3 0 0 3 3 3 2 Myosin-like coiled-coil protein Laminin_I PF06008.9 KZN92960.1 - 1.8 7.8 35.6 0.29 10.4 10.1 3.1 1 1 1 2 2 2 0 Laminin Domain I DUF904 PF06005.7 KZN92960.1 - 2.7 8.3 47.8 0.21 11.8 2.6 5.1 3 1 2 5 5 5 0 Protein of unknown function (DUF904) ERM PF00769.14 KZN92960.1 - 6.1 6.3 55.5 0.048 13.1 12.5 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 KZN92960.1 - 7 6.4 32.4 3.3 7.4 4.6 4.0 2 2 2 4 4 4 0 Laminin Domain II TMF_TATA_bd PF12325.3 KZN92960.1 - 9.1 6.0 43.3 0.99 9.1 4.0 4.2 3 2 1 4 4 4 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 KZN92960.1 - 9.7 6.0 50.3 0.88 9.4 7.9 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding M16C_assoc PF08367.6 KZN92961.1 - 2.3e-53 180.6 0.0 9.2e-53 178.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KZN92961.1 - 2.4e-24 86.0 0.0 5.4e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KZN92961.1 - 2.5e-08 33.7 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Methyltransf_25 PF13649.1 KZN92963.1 - 2.6e-06 27.7 0.1 4.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN92963.1 - 0.0078 15.8 1.4 0.018 14.6 1.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN92963.1 - 0.011 16.1 0.4 0.018 15.5 0.3 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KZN92963.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NST1 PF13945.1 KZN92965.1 - 0.082 12.9 1.5 0.19 11.7 1.0 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Methyltransf_16 PF10294.4 KZN92966.1 - 5.5e-49 165.9 0.0 8.5e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KZN92966.1 - 0.0042 17.6 0.0 0.014 15.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN92966.1 - 0.018 15.0 0.1 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KZN92966.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Orn_Arg_deC_N PF02784.11 KZN92967.1 - 5.5e-77 258.3 0.0 7.3e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KZN92967.1 - 2.7e-31 107.6 0.0 5.3e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KZN92967.1 - 0.033 13.4 0.0 0.061 12.6 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel cobW PF02492.14 KZN92968.1 - 1.5e-26 92.9 0.0 1.4e-23 83.2 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KZN92968.1 - 0.0014 18.3 0.0 0.0066 16.1 0.0 2.1 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 KZN92968.1 - 0.0087 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KZN92968.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KZN92968.1 - 0.021 15.1 0.1 0.056 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 KZN92968.1 - 0.038 13.2 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 KZN92968.1 - 0.055 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KZN92968.1 - 0.11 12.0 0.2 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KZN92968.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KZN92968.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DSBA PF01323.15 KZN92969.1 - 5.8e-22 78.1 0.0 6.7e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain T2SK PF03934.8 KZN92969.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K DIOX_N PF14226.1 KZN92971.1 - 4.7e-18 65.8 0.1 1.7e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN92971.1 - 1.7e-10 41.0 0.0 5.6e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KZN92972.1 - 6.4e-30 104.0 27.7 7e-30 103.9 16.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0016 PF01169.14 KZN92972.1 - 0.098 12.8 1.5 14 5.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF3278 PF11683.3 KZN92972.1 - 0.96 9.4 4.8 4 7.4 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Abhydrolase_5 PF12695.2 KZN92973.1 - 1.4e-11 44.3 0.0 3.2e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN92973.1 - 2.3e-09 37.4 0.3 4e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN92973.1 - 0.00091 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KZN92973.1 - 0.0049 16.4 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KZN92973.1 - 0.0061 16.3 0.1 0.036 13.9 0.1 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Na_Pi_cotrans PF02690.10 KZN92973.1 - 0.015 15.0 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter Cutinase PF01083.17 KZN92973.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Cutinase TLD PF07534.11 KZN92975.1 - 1.1e-21 77.2 0.0 2.9e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 TLD IMPDH PF00478.20 KZN92977.1 - 3e-129 430.9 2.9 3.4e-129 430.7 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KZN92977.1 - 2.3e-18 65.7 0.0 2.5e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KZN92977.1 - 4.2e-07 29.4 11.4 0.0024 17.0 1.1 3.2 2 1 0 3 3 3 3 Nitronate monooxygenase FMN_dh PF01070.13 KZN92977.1 - 7.7e-06 24.9 2.7 1.5e-05 23.9 1.9 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KZN92977.1 - 0.00016 21.0 3.8 0.0035 16.6 2.6 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 KZN92977.1 - 0.0053 15.6 1.1 0.15 10.8 0.1 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 KZN92977.1 - 0.049 12.6 4.1 0.058 12.4 0.3 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG RTA1 PF04479.8 KZN92978.1 - 2.6e-27 95.7 1.7 3.1e-27 95.5 1.2 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4401 PF14351.1 KZN92978.1 - 0.0053 15.7 1.3 0.0069 15.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) NMT PF01233.14 KZN92979.1 - 2.5e-79 264.5 0.3 6.4e-79 263.2 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KZN92979.1 - 5.8e-77 257.3 0.1 1.3e-76 256.2 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KZN92979.1 - 3.1e-07 30.2 0.0 5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN92979.1 - 0.0015 18.6 0.2 0.0047 17.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF427 PF04248.7 KZN92979.1 - 0.023 14.3 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Mur_ligase_M PF08245.7 KZN92980.1 - 2.5e-09 37.4 1.3 2.3e-07 31.0 0.4 3.6 2 1 0 2 2 2 1 Mur ligase middle domain Syja_N PF02383.13 KZN92981.1 - 7.9e-93 310.7 0.0 9.9e-93 310.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 KZN92982.1 - 5.6e-59 198.1 0.2 6.5e-59 197.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KZN92982.1 - 7e-20 71.6 0.1 1.6e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KZN92982.1 - 6.8e-15 54.7 0.0 8.5e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KZN92982.1 - 2.3e-08 33.7 0.0 4.1e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KZN92982.1 - 4e-08 32.6 0.0 4.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN92982.1 - 6.1e-06 26.1 0.0 8.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KZN92982.1 - 0.005 16.9 0.0 0.48 10.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KZN92982.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN92982.1 - 0.041 13.8 0.3 0.11 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KZN92982.1 - 0.079 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mitofilin PF09731.4 KZN92983.1 - 2.7e-146 488.5 28.5 5.8e-146 487.5 19.7 1.5 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Med30 PF11315.3 KZN92983.1 - 1.5 8.9 8.0 2.1 8.4 4.4 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF479 PF04336.7 KZN92983.1 - 2.3 8.3 7.6 4 7.5 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function, DUF479 DUF2115 PF09888.4 KZN92983.1 - 9.2 6.3 7.7 12 5.9 2.2 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) 4HBT_3 PF13622.1 KZN92985.1 - 0.035 13.8 3.2 0.041 13.6 0.3 2.1 2 0 0 2 2 2 0 Thioesterase-like superfamily GTP_EFTU PF00009.22 KZN92986.1 - 1.5e-55 187.5 0.2 2.6e-55 186.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KZN92986.1 - 1.7e-32 111.0 0.0 3.7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KZN92986.1 - 1.7e-29 101.8 0.1 4.6e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KZN92986.1 - 4e-23 81.0 0.0 1.1e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KZN92986.1 - 2.6e-12 46.6 0.0 6.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_L36 PF00444.13 KZN92987.1 - 3.9e-10 39.5 3.0 7.1e-10 38.7 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 PALP PF00291.20 KZN92988.1 - 3.8e-73 246.4 0.3 6.4e-73 245.6 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KZN92988.1 - 5e-46 154.2 0.0 2.2e-22 78.4 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 KZN92989.1 - 5.4e-27 93.2 0.1 7.6e-27 92.8 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ATP-synt_E PF05680.7 KZN92989.1 - 4.2 7.3 7.9 1.3 9.0 3.0 1.9 1 1 1 2 2 2 0 ATP synthase E chain MARVEL PF01284.18 KZN92990.1 - 4.7e-14 52.4 8.0 6.5e-14 51.9 5.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Pkinase PF00069.20 KZN92991.1 - 1.6e-54 184.8 0.0 1.9e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN92991.1 - 2.1e-22 79.4 0.0 2.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN92991.1 - 5e-05 22.4 0.1 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN92991.1 - 0.00033 19.7 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KZN92991.1 - 0.0027 17.0 0.1 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN92991.1 - 0.0034 17.1 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KZN92991.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Complex1_LYR PF05347.10 KZN92992.1 - 5.3e-15 54.9 0.1 8.9e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KZN92992.1 - 1.1e-13 51.2 0.1 1.6e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KZN92992.1 - 0.067 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Aldedh PF00171.17 KZN92993.1 - 6.4e-164 545.6 0.4 7.3e-164 545.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KZN92993.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RRN9 PF10680.4 KZN92995.1 - 1.7e-14 53.2 1.4 8.5e-14 51.0 0.9 2.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 KZN92995.1 - 6.2 7.3 7.3 0.89 10.0 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PD40 PF07676.7 KZN92996.1 - 7.7e-38 127.5 26.8 1.2e-06 28.0 0.4 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KZN92996.1 - 5.7e-15 54.7 2.3 0.00024 19.8 0.2 6.3 5 1 0 6 6 6 6 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 KZN92996.1 - 0.31 11.0 4.8 45 4.1 0.1 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat KR PF08659.5 KZN92997.1 - 1.1e-26 93.6 0.7 1.7e-26 93.0 0.5 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KZN92997.1 - 2.4e-18 66.6 0.3 4e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase YchF-GTPase_C PF06071.8 KZN92998.1 - 3.6e-36 122.8 0.1 8.8e-36 121.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KZN92998.1 - 1.7e-16 60.1 0.0 2.7e-16 59.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN92998.1 - 1.2e-06 27.8 0.0 2.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Trypsin_2 PF13365.1 KZN92999.1 - 0.0014 18.5 0.0 0.0042 17.0 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.16 KZN92999.1 - 0.045 13.1 0.1 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease NAD_binding_2 PF03446.10 KZN93000.1 - 5.2e-17 62.1 0.0 7.8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KZN93000.1 - 4.8e-07 29.8 0.0 8.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF3405 PF11885.3 KZN93001.1 - 5.6e-105 351.4 1.4 1.1e-104 350.5 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) DUF3405 PF11885.3 KZN93002.1 - 1.6e-08 33.2 0.8 2.2e-08 32.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Pescadillo_N PF06732.6 KZN93003.1 - 1.4e-115 385.4 0.0 1.4e-115 385.4 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KZN93003.1 - 1.9e-07 31.1 0.0 1.9e-06 27.9 0.0 2.7 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 KZN93004.1 - 2.8e-121 404.9 24.5 3.2e-121 404.7 17.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 KZN93004.1 - 5.6e-05 22.9 0.3 0.00011 21.9 0.2 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) Acetyltransf_1 PF00583.19 KZN93005.1 - 1.7e-16 59.9 0.0 2.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KZN93005.1 - 5e-06 26.1 0.0 8.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KZN93005.1 - 9.9e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN93005.1 - 0.00026 21.0 0.1 0.00041 20.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN93005.1 - 0.031 14.4 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN93005.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN93005.1 - 0.16 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain APH PF01636.18 KZN93006.1 - 4.6e-13 49.4 0.0 1e-12 48.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93006.1 - 0.002 17.7 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN93006.1 - 0.0056 15.8 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.6 KZN93006.1 - 0.01 14.4 0.0 0.68 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.9 KZN93006.1 - 0.053 12.5 0.0 6.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.21 KZN93007.1 - 1.8e-27 95.4 0.6 2.8e-27 94.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN93007.1 - 2e-16 61.0 0.1 5.8e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN93007.1 - 6.2e-14 51.6 0.1 2e-13 50.0 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KZN93007.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Raffinose_syn PF05691.7 KZN93008.1 - 4.5e-50 169.9 0.5 1.6e-47 161.5 0.8 2.6 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KZN93008.1 - 1.7e-06 27.0 0.2 2.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 KZN93009.1 - 3.2e-70 236.5 0.0 4.2e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MutS_V PF00488.16 KZN93010.1 - 1.3e-80 270.1 0.0 2.3e-80 269.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN93010.1 - 1.3e-50 172.0 0.0 2.6e-50 171.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KZN93010.1 - 6.3e-33 113.1 0.2 1.4e-32 112.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KZN93010.1 - 5.7e-16 58.8 0.0 1.5e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KZN93010.1 - 2.5e-14 53.1 0.5 5.2e-14 52.1 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KZN93010.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCPVI PF02993.9 KZN93012.1 - 0.39 10.8 2.9 0.58 10.2 2.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF1990 PF09348.5 KZN93013.1 - 0.045 13.3 0.1 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) RelB PF04221.7 KZN93013.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin HTH_10 PF04967.7 KZN93014.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Peptidase_M28 PF04389.12 KZN93016.1 - 3.4e-32 111.6 0.0 4.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.9 KZN93017.1 - 8.2e-17 60.9 16.1 1.1e-10 41.4 3.4 4.7 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 KZN93017.1 - 2e-10 40.2 1.1 2e-10 40.2 0.7 3.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4341) FAD_binding_4 PF01565.18 KZN93018.1 - 2.2e-27 95.2 1.3 4.3e-27 94.2 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN93018.1 - 7.9e-13 48.0 0.0 1.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like LigD_N PF13298.1 KZN93019.1 - 5.3e-28 97.2 0.1 1.1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) ABC_tran PF00005.22 KZN93020.1 - 1.7e-47 161.1 0.0 8.1e-30 103.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN93020.1 - 1.1e-32 113.5 31.1 1e-19 71.0 7.3 4.0 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KZN93020.1 - 3.2e-10 39.6 0.0 0.01 15.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KZN93020.1 - 0.00013 21.4 0.0 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KZN93020.1 - 0.00019 21.4 2.4 0.047 13.6 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KZN93020.1 - 0.00023 20.1 0.0 0.16 10.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KZN93020.1 - 0.00093 18.6 1.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN93020.1 - 0.0015 18.6 0.0 4 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KZN93020.1 - 0.0019 18.2 0.0 7 6.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KZN93020.1 - 0.0019 17.6 0.8 1.2 8.4 0.0 3.3 4 0 0 4 4 4 1 AAA-like domain DUF87 PF01935.12 KZN93020.1 - 0.0021 17.9 0.7 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KZN93020.1 - 0.0027 17.6 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KZN93020.1 - 0.0035 16.5 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KZN93020.1 - 0.0043 17.4 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KZN93020.1 - 0.011 16.2 0.1 5.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KZN93020.1 - 0.021 13.8 0.1 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KZN93020.1 - 0.073 12.5 0.0 12 5.2 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 KZN93020.1 - 0.092 12.6 0.8 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit LST1 PF05083.8 KZN93020.1 - 0.17 11.9 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 LST-1 protein tRNA-synt_2 PF00152.15 KZN93021.1 - 1.5e-101 339.5 0.0 1.3e-60 204.9 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN93021.1 - 5.9e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Cutinase PF01083.17 KZN93022.1 - 1.7e-44 151.7 1.4 2.3e-44 151.2 1.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KZN93022.1 - 0.0065 15.9 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 KZN93022.1 - 0.0084 15.8 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KZN93022.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.6 KZN93022.1 - 0.061 13.1 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) UbiA PF01040.13 KZN93023.1 - 1.3e-27 96.6 19.0 1.9e-27 96.0 13.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.9 KZN93024.1 - 3.9e-22 77.5 5.2 5.4e-11 41.8 0.8 2.8 2 1 0 2 2 2 2 PQ loop repeat DoxX_3 PF13781.1 KZN93024.1 - 0.085 13.2 0.6 0.085 13.2 0.4 2.1 2 0 0 2 2 2 0 DoxX-like family Med8 PF10232.4 KZN93025.1 - 3.6e-53 180.4 0.0 4.2e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Myc_N PF01056.13 KZN93025.1 - 0.0078 15.4 0.2 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Med11 PF10280.4 KZN93025.1 - 0.093 12.7 1.4 0.11 12.5 0.3 1.6 2 0 0 2 2 2 0 Mediator complex protein RCR PF12273.3 KZN93026.1 - 1.9e-06 28.4 4.9 3.7e-06 27.5 3.4 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 KZN93026.1 - 0.03 14.0 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KZN93026.1 - 0.06 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PsbX PF06596.6 KZN93026.1 - 0.5 10.0 4.3 0.77 9.4 2.1 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DctM PF06808.7 KZN93027.1 - 0.036 12.6 0.7 0.049 12.1 0.5 1.1 1 0 0 1 1 1 0 DctM-like transporters PMI_typeI PF01238.16 KZN93028.1 - 4.5e-59 200.3 0.1 2.1e-57 194.8 0.1 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KZN93028.1 - 0.0047 16.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Glyco_hydro_92 PF07971.7 KZN93031.1 - 2.1e-167 557.8 0.1 2.6e-167 557.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bac_rhamnosid PF05592.6 KZN93032.1 - 6.3e-18 64.2 0.0 1.7e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KZN93032.1 - 7.1e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain LEA_2 PF03168.8 KZN93032.1 - 0.013 15.8 0.0 6.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Late embryogenesis abundant protein Sugar_tr PF00083.19 KZN93033.1 - 4.1e-64 216.8 29.7 1.5e-62 211.6 20.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93033.1 - 9e-17 60.8 31.2 1.8e-08 33.5 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN93033.1 - 3.2e-06 25.6 9.2 0.002 16.3 3.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Tetraspannin PF00335.15 KZN93033.1 - 0.0053 16.0 2.6 0.0053 16.0 1.8 2.5 2 0 0 2 2 2 1 Tetraspanin family DUF1680 PF07944.7 KZN93035.1 - 2.4e-133 445.1 0.2 2.7e-133 444.9 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) 4HBT PF03061.17 KZN93036.1 - 7.1e-12 45.2 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.15 KZN93037.1 - 3.9e-72 241.0 0.0 4.7e-72 240.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KZN93037.1 - 5.1e-08 32.8 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KZN93037.1 - 1.5e-05 25.3 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KZN93037.1 - 3.7e-05 24.5 0.0 6.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KZN93037.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KZN93037.1 - 0.0021 17.3 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KZN93037.1 - 0.057 12.9 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KZN93037.1 - 0.074 13.1 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 KZN93037.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KZN93037.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin V-ATPase_C PF03223.10 KZN93038.1 - 1.1e-120 402.9 0.1 1.3e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NMT PF01233.14 KZN93038.1 - 0.12 11.9 0.5 0.22 11.1 0.3 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain RhoGAP PF00620.22 KZN93039.1 - 1.5e-46 157.7 0.8 2.9e-46 156.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KZN93039.1 - 6.7e-15 54.8 19.4 1.2e-09 38.1 1.8 2.4 2 0 0 2 2 2 2 LIM domain HAUS6_N PF14661.1 KZN93039.1 - 0.023 14.0 3.0 0.045 13.1 2.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_Maf PF03131.12 KZN93039.1 - 0.11 12.7 8.1 0.19 12.0 1.6 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.1 KZN93039.1 - 0.18 10.9 10.9 0.012 14.8 3.8 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 OmpH PF03938.9 KZN93039.1 - 0.53 10.2 8.3 1.3 8.9 5.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Zn-ribbon_8 PF09723.5 KZN93039.1 - 2.2 8.3 19.8 0.25 11.3 1.1 4.0 3 1 1 4 4 4 0 Zinc ribbon domain CENP-F_leu_zip PF10473.4 KZN93039.1 - 2.7 7.8 17.2 0.33 10.7 4.3 3.4 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KZN93039.1 - 4.6 7.6 10.1 1 9.7 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CENP-H PF05837.7 KZN93039.1 - 9.9 6.3 13.9 0.082 13.0 1.8 3.2 3 1 0 3 3 3 0 Centromere protein H (CENP-H) DUF423 PF04241.10 KZN93040.1 - 0.45 10.4 2.4 0.28 11.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF423) FKBP_C PF00254.23 KZN93041.1 - 9e-29 99.3 0.0 1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AP_endonuc_2 PF01261.19 KZN93042.1 - 1.2e-27 96.6 0.0 1.5e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GFO_IDH_MocA PF01408.17 KZN93043.1 - 1.1e-27 96.8 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KZN93043.1 - 1.4e-17 63.5 0.0 6.2e-17 61.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KZN93043.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 KZN93043.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain Gp_dh_N PF00044.19 KZN93043.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KZN93044.1 - 1.5e-132 442.4 24.0 1.7e-132 442.2 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93044.1 - 3.6e-23 81.8 42.1 9.4e-23 80.4 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RhodobacterPufX PF11511.3 KZN93044.1 - 0.16 11.4 1.0 23 4.4 0.0 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX APH PF01636.18 KZN93045.1 - 9.9e-13 48.3 0.6 2.4e-11 43.8 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93045.1 - 8.5e-05 22.2 0.2 0.00038 20.1 0.0 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase Shikimate_dh_N PF08501.6 KZN93046.1 - 8.1e-21 73.8 0.0 2.1e-20 72.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KZN93046.1 - 1.5e-14 54.2 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.20 KZN93047.1 - 5.4e-80 268.5 0.0 6.1e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family APH PF01636.18 KZN93048.1 - 8.5e-09 35.4 4.3 2.2e-08 34.1 3.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93048.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase DHquinase_I PF01487.10 KZN93049.1 - 2.4e-47 161.4 0.0 3.5e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KZN93049.1 - 1.4e-20 73.7 0.0 3.1e-20 72.6 0.0 1.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KZN93049.1 - 6.4e-18 64.5 0.0 1.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KZN93049.1 - 3.3e-10 40.1 0.0 9.1e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 KZN93049.1 - 0.034 14.9 0.0 0.071 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KZN93049.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.12 KZN93049.1 - 0.16 12.3 0.1 0.72 10.3 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.13 KZN93050.1 - 1.7e-21 76.2 0.0 2.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93050.1 - 7.1e-07 29.0 17.4 1.1e-06 28.4 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_II PF01220.14 KZN93051.1 - 2.3e-61 205.2 0.1 2.6e-61 205.0 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Arrestin_C PF02752.17 KZN93052.1 - 0.00025 21.1 0.0 0.83 9.7 0.1 2.4 1 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KZN93052.1 - 0.00063 19.5 0.0 0.0032 17.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KZN93052.1 - 0.0033 16.9 0.2 0.0073 15.8 0.1 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like Fungal_trans_2 PF11951.3 KZN93053.1 - 2.9e-33 115.0 8.6 5.4e-33 114.1 5.9 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93053.1 - 1.6e-06 27.9 9.3 4.2e-06 26.5 6.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.15 KZN93054.1 - 4.7e-42 143.9 0.0 1.2e-40 139.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KZN93054.1 - 2e-09 37.5 0.3 4.1e-09 36.5 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.7 KZN93055.1 - 6.9e-48 160.7 17.4 9.8e-28 96.2 3.2 3.2 3 0 0 3 3 3 3 CHORD CS PF04969.11 KZN93055.1 - 1e-13 51.6 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 KZN93056.1 - 6.2e-15 55.2 0.0 7.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KZN93056.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.1 KZN93056.1 - 0.023 14.8 0.0 0.032 14.4 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain HTH_Tnp_4 PF13613.1 KZN93057.1 - 0.22 11.0 1.8 0.66 9.5 1.3 1.9 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Methyltransf_31 PF13847.1 KZN93058.1 - 9.4e-31 106.4 0.0 1.4e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93058.1 - 5.5e-18 65.2 0.0 1.6e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN93058.1 - 2.1e-16 59.7 0.0 4.3e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KZN93058.1 - 2.3e-13 50.7 0.0 4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93058.1 - 3.1e-13 49.9 0.0 7.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN93058.1 - 1.9e-12 47.1 0.0 3.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN93058.1 - 6.7e-11 42.2 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KZN93058.1 - 2.7e-09 36.6 0.1 7.1e-09 35.1 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KZN93058.1 - 3.5e-09 36.4 0.1 6.4e-09 35.6 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KZN93058.1 - 8e-07 29.4 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN93058.1 - 1.4e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 KZN93058.1 - 0.0003 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 KZN93058.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.8 KZN93058.1 - 0.0011 18.3 0.1 0.0032 16.8 0.0 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 KZN93058.1 - 0.0032 16.5 0.0 0.008 15.2 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase NNMT_PNMT_TEMT PF01234.12 KZN93058.1 - 0.004 16.1 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 KZN93058.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KZN93058.1 - 0.0082 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN93058.1 - 0.035 13.1 0.0 0.075 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.10 KZN93058.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase SBF PF01758.11 KZN93059.1 - 3.1e-51 173.4 11.5 3.1e-51 173.4 8.0 2.6 3 1 0 3 3 3 1 Sodium Bile acid symporter family Rhodanese PF00581.15 KZN93060.1 - 6e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain DUF3425 PF11905.3 KZN93061.1 - 1.9e-26 92.5 0.1 3e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KZN93061.1 - 0.016 15.1 8.4 0.035 14.0 5.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.20 KZN93062.1 - 1.3e-11 44.7 0.1 4.5e-11 42.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN93062.1 - 0.00028 20.5 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KZN93062.1 - 0.084 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 14-3-3 PF00244.15 KZN93065.1 - 4.8e-11 42.1 0.3 1.5e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 14-3-3 protein Toxin_15 PF07906.8 KZN93065.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Metallophos PF00149.23 KZN93066.1 - 2.9e-09 36.6 0.8 7.4e-09 35.2 0.5 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 KZN93067.1 - 3.2e-80 269.9 25.0 3.6e-80 269.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93067.1 - 4.5e-30 104.5 28.8 6.4e-30 104.0 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN93067.1 - 0.0093 14.2 6.1 0.0061 14.8 1.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KZN93067.1 - 0.11 12.5 5.1 0.24 11.4 0.2 3.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1228) MFS_3 PF05977.8 KZN93067.1 - 0.47 8.5 10.3 0.11 10.6 0.9 3.0 3 1 0 3 3 3 0 Transmembrane secretion effector GMC_oxred_N PF00732.14 KZN93068.1 - 4.4e-46 157.3 0.3 2.7e-45 154.8 0.2 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN93068.1 - 1.5e-29 103.1 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KZN93068.1 - 5.9e-10 38.5 0.7 1.3e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN93068.1 - 8.3e-07 28.1 2.1 0.012 14.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN93068.1 - 3.5e-05 23.7 0.1 8.1e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN93068.1 - 0.00017 20.6 0.1 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN93068.1 - 0.02 13.3 0.1 0.034 12.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KZN93068.1 - 0.054 13.5 0.1 1.3 9.0 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN93068.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Oxidored_q2 PF00420.19 KZN93069.1 - 1.6 8.3 7.5 0.73 9.4 0.2 3.1 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L APH PF01636.18 KZN93071.1 - 3.8e-08 33.3 0.0 1.6e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93071.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transferase PF02458.10 KZN93072.1 - 8.8e-19 67.2 0.0 7.4e-15 54.3 0.0 2.0 2 0 0 2 2 2 2 Transferase family ketoacyl-synt PF00109.21 KZN93073.1 - 2e-79 266.6 0.0 3.9e-79 265.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN93073.1 - 4.6e-70 236.4 0.2 7.3e-70 235.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KZN93073.1 - 1.6e-47 161.5 0.0 4.5e-47 160.0 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KZN93073.1 - 2.3e-44 151.7 0.0 5.1e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KZN93073.1 - 2.7e-43 147.7 1.0 6.9e-43 146.4 0.1 2.2 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KZN93073.1 - 2.1e-39 134.0 0.2 1.5e-38 131.2 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KZN93073.1 - 8.3e-20 71.1 0.0 3.5e-19 69.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KZN93073.1 - 2.3e-17 62.7 0.0 1.2e-16 60.3 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KZN93073.1 - 5.5e-12 45.7 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93073.1 - 7.6e-11 42.3 0.0 2.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93073.1 - 1.5e-09 37.6 0.0 7.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 KZN93073.1 - 3.5e-07 29.9 0.1 8.5e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 KZN93073.1 - 4.8e-07 30.0 0.0 4e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93073.1 - 5e-07 30.2 0.0 4.7e-06 27.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KZN93073.1 - 2.7e-06 27.5 0.1 9.1e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KZN93073.1 - 3.1e-06 26.4 0.0 6.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KZN93073.1 - 5.1e-06 25.6 0.1 1.1e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.1 KZN93073.1 - 2.3e-05 25.2 0.0 0.00021 22.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 KZN93073.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FSH1 PF03959.8 KZN93074.1 - 6.9e-27 94.2 0.0 3.2e-26 92.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KZN93074.1 - 0.0028 17.4 0.0 0.0047 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family EMP24_GP25L PF01105.19 KZN93075.1 - 7.6e-48 162.6 0.4 8.8e-48 162.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glycoprotein PF03409.10 KZN93075.1 - 0.074 11.7 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein PAM2 PF07145.10 KZN93076.1 - 0.94 9.1 15.4 0.51 9.9 0.0 4.3 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.13 KZN93077.1 - 9.1e-32 110.3 0.0 3.3e-31 108.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GLE1 PF07817.8 KZN93078.1 - 1.3e-15 57.0 0.0 1.3e-15 57.0 0.0 2.7 1 1 2 3 3 3 1 GLE1-like protein Peptidase_S64 PF08192.6 KZN93078.1 - 3.2 5.9 13.7 4.6 5.4 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 LMBR1 PF04791.11 KZN93078.1 - 8.4 4.8 10.7 13 4.2 7.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein RNB PF00773.14 KZN93079.1 - 1.7e-82 277.3 0.2 5.9e-81 272.2 0.0 2.3 2 0 0 2 2 2 2 RNB domain UQ_con PF00179.21 KZN93080.1 - 1.2e-34 118.7 0.0 1.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KZN93080.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Macoilin PF09726.4 KZN93081.1 - 2.3 6.4 12.0 2.3 6.3 8.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 KZN93081.1 - 5 6.5 11.8 6 6.2 8.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MMgT PF10270.4 KZN93082.1 - 8.7e-34 116.1 0.0 9.9e-34 115.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 KZN93084.1 - 7.8e-32 108.8 1.8 1.3e-31 108.1 1.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KZN93084.1 - 8.7e-12 44.9 2.1 8.7e-12 44.9 1.5 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 KZN93084.1 - 7.2e-05 22.6 0.4 0.00024 21.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KZN93084.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN93084.1 - 0.0071 16.2 0.3 0.11 12.3 0.2 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4604 PF15377.1 KZN93084.1 - 1.3 9.1 10.2 2.2 8.4 7.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) AAA_2 PF07724.9 KZN93085.1 - 5e-45 153.4 0.0 5.8e-44 150.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KZN93085.1 - 6.2e-26 90.1 0.2 1.7e-25 88.6 0.2 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KZN93085.1 - 8.4e-20 71.3 0.1 6e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN93085.1 - 2.2e-12 46.8 0.0 4.8e-08 32.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KZN93085.1 - 1.2e-10 41.6 0.6 0.00099 19.2 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 KZN93085.1 - 1.3e-10 41.5 11.8 0.0002 21.4 0.0 5.0 4 2 1 6 6 4 3 AAA ATPase domain AAA_14 PF13173.1 KZN93085.1 - 2.1e-07 30.8 0.4 0.034 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KZN93085.1 - 1e-06 28.3 0.5 0.0002 20.8 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KZN93085.1 - 3.9e-06 26.6 0.1 0.086 12.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 KZN93085.1 - 5e-06 26.3 5.7 0.04 13.5 0.1 4.5 3 2 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 KZN93085.1 - 7.5e-06 26.7 4.6 0.089 13.6 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KZN93085.1 - 4.9e-05 23.3 0.5 0.049 13.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 KZN93085.1 - 9.4e-05 22.1 0.0 0.045 13.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KZN93085.1 - 0.00012 20.8 0.2 0.088 11.4 0.0 2.9 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 KZN93085.1 - 0.00017 21.0 0.0 0.86 9.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KZN93085.1 - 0.00018 21.2 0.0 0.0098 15.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 KZN93085.1 - 0.0003 20.2 0.1 0.047 13.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KZN93085.1 - 0.00044 19.7 0.3 0.12 11.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN93085.1 - 0.001 19.3 7.6 0.19 12.0 0.0 3.3 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.17 KZN93085.1 - 0.0011 19.1 0.0 0.71 10.0 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KZN93085.1 - 0.0027 16.8 0.1 2.1 7.4 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KZN93085.1 - 0.0044 16.5 0.1 0.18 11.2 0.0 2.9 2 2 0 2 2 2 1 AAA-like domain DUF853 PF05872.7 KZN93085.1 - 0.0052 15.2 0.1 0.067 11.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_24 PF13479.1 KZN93085.1 - 0.0064 16.0 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KZN93085.1 - 0.0073 15.4 0.0 0.34 9.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 KZN93085.1 - 0.0078 16.5 1.7 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.1 KZN93085.1 - 0.0085 15.6 4.0 0.2 11.2 0.0 4.0 3 1 2 5 5 4 1 AAA domain DUF815 PF05673.8 KZN93085.1 - 0.0094 14.9 0.7 0.29 10.0 0.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KZN93085.1 - 0.0096 15.8 0.0 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KZN93085.1 - 0.012 15.1 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 KZN93085.1 - 0.015 15.1 8.0 0.93 9.2 0.0 3.9 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 KZN93085.1 - 0.016 14.7 0.1 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 KZN93085.1 - 0.028 14.0 0.1 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KZN93085.1 - 0.029 13.5 0.1 5 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DNA_pol3_delta2 PF13177.1 KZN93085.1 - 0.048 13.3 0.0 1.8 8.1 0.0 2.8 3 1 0 3 3 2 0 DNA polymerase III, delta subunit Miro PF08477.8 KZN93085.1 - 0.081 13.4 1.6 1.7 9.1 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_29 PF13555.1 KZN93085.1 - 0.15 11.5 0.1 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2968 PF11180.3 KZN93085.1 - 0.34 10.2 8.3 0.73 9.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4446 PF14584.1 KZN93085.1 - 0.63 9.8 2.8 1.1 9.0 0.8 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF4446) APG6 PF04111.7 KZN93085.1 - 3 6.7 9.4 5.2 6.0 6.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Endonuc_Holl PF10107.4 KZN93085.1 - 3.3 7.3 7.0 8 6.1 0.0 3.4 4 0 0 4 4 3 0 Endonuclease related to archaeal Holliday junction resolvase Cortex-I_coil PF09304.5 KZN93085.1 - 4.4 7.4 20.1 13 5.8 9.7 3.2 2 1 0 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.10 KZN93085.1 - 9.4 5.8 11.4 17 4.9 4.3 2.7 1 1 1 2 2 2 0 Septum formation initiator MutS_V PF00488.16 KZN93086.1 - 2.9e-58 197.0 0.0 4.6e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KZN93086.1 - 1.7e-17 63.8 0.0 2.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KZN93086.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA PF00004.24 KZN93086.1 - 0.034 14.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KZN93086.1 - 0.081 12.4 0.0 0.39 10.2 0.0 2.1 2 1 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.20 KZN93087.1 - 3.7e-45 154.1 0.0 5.2e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93087.1 - 2.8e-18 65.9 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN93087.1 - 3e-05 23.1 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KZN93087.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10 PF09368.5 KZN93088.1 - 4.2e-28 97.3 9.4 4.2e-28 97.3 6.5 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KZN93088.1 - 8.7e-16 57.9 0.0 8.7e-16 57.9 0.0 2.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 KZN93089.1 - 3.8e-19 69.2 0.1 5.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN93089.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN93089.1 - 2.3e-06 27.5 0.0 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KZN93089.1 - 4.8e-06 26.6 1.8 0.00055 19.9 0.6 2.9 2 2 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KZN93089.1 - 1.9e-05 24.2 0.2 4.6e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KZN93089.1 - 0.0019 17.2 0.3 0.0033 16.5 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KZN93089.1 - 0.0024 17.9 0.0 0.0063 16.6 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KZN93089.1 - 0.016 15.4 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KZN93089.1 - 0.034 13.9 0.1 0.064 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Eno-Rase_NADH_b PF12242.3 KZN93089.1 - 0.048 13.4 0.2 0.2 11.4 0.4 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Disulph_isomer PF06491.6 KZN93089.1 - 0.082 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Disulphide isomerase FA_hydroxylase PF04116.8 KZN93090.1 - 2.9e-14 53.4 9.9 2.9e-14 53.4 6.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 KZN93091.1 - 2.8e-38 130.4 0.3 4.5e-38 129.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Imm44 PF15584.1 KZN93091.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 44 DUF1070 PF06376.7 KZN93091.1 - 0.31 10.9 2.6 0.29 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1070) Proteasom_Rpn13 PF04683.8 KZN93092.1 - 7.8e-29 99.5 0.0 1.2e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 KZN93093.1 - 7.1e-99 329.0 78.6 1e-34 119.5 4.0 5.4 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 KZN93093.1 - 0.0074 15.5 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 EF hand PKD_channel PF08016.7 KZN93093.1 - 0.041 12.3 61.1 0.13 10.6 8.8 7.1 5 2 1 7 7 7 0 Polycystin cation channel EF-hand_6 PF13405.1 KZN93093.1 - 0.083 12.8 0.0 0.52 10.3 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain Hamartin PF04388.7 KZN93094.1 - 0.5 8.9 7.6 0.57 8.7 5.3 1.0 1 0 0 1 1 1 0 Hamartin protein ORC6 PF05460.8 KZN93094.1 - 4.7 6.2 6.5 5.3 6.0 4.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SET PF00856.23 KZN93095.1 - 1.7e-22 80.4 0.1 3.6e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 KZN93095.1 - 1.2e-11 44.7 4.5 1.2e-11 44.7 3.1 2.4 2 1 0 2 2 2 1 Pre-SET motif Pkinase PF00069.20 KZN93096.1 - 3.7e-76 255.6 0.0 5.9e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93096.1 - 3.9e-40 137.5 0.0 8e-40 136.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KZN93096.1 - 1.6e-17 62.6 0.3 2.5e-17 62.0 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KZN93096.1 - 4.6e-06 25.8 0.0 8.6e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN93096.1 - 6.1e-05 22.1 0.0 0.00071 18.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KZN93096.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KZN93096.1 - 0.0016 18.2 0.0 0.015 14.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KZN93096.1 - 0.0081 15.4 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KZN93096.1 - 0.023 14.0 0.3 0.085 12.1 0.2 1.9 1 1 0 1 1 1 0 RIO1 family DUF2823 PF11034.3 KZN93097.1 - 5.1e-30 103.3 14.3 5.7e-30 103.2 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF221 PF02714.10 KZN93098.1 - 1.2e-92 310.2 18.0 1.2e-92 310.2 12.4 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KZN93098.1 - 1.2e-43 148.3 1.6 1.2e-43 148.3 1.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KZN93098.1 - 1e-15 58.0 0.0 2.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3445 PF11927.3 KZN93100.1 - 5.1e-84 281.5 0.0 5.9e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.14 KZN93101.1 - 1.4e-51 174.7 0.0 1.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KZN93101.1 - 6.3e-14 52.3 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 KZN93102.1 - 1.6e-31 108.2 7.7 1.6e-31 108.2 5.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) HMG_box PF00505.14 KZN93104.1 - 9.8e-25 86.6 2.0 9.8e-25 86.6 1.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KZN93104.1 - 5.4e-19 68.3 1.0 5.4e-19 68.3 0.7 1.8 2 1 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 KZN93104.1 - 0.029 14.1 2.2 0.068 12.9 1.5 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF1014 PF06244.7 KZN93104.1 - 0.1 12.8 3.6 0.12 12.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) CENP-H PF05837.7 KZN93105.1 - 1.3e-29 102.4 8.9 1.3e-29 102.4 6.2 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF641 PF04859.7 KZN93105.1 - 0.2 11.4 6.5 1.5 8.6 1.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Mnd1 PF03962.10 KZN93105.1 - 1.3 8.6 8.9 0.42 10.2 2.0 2.1 2 0 0 2 2 2 0 Mnd1 family TBPIP PF07106.8 KZN93105.1 - 3.4 7.1 8.8 0.53 9.8 2.6 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG11 PF10377.4 KZN93106.1 - 1.3e-39 135.0 0.0 1.3e-39 135.0 0.0 2.9 3 1 0 3 3 3 1 Autophagy-related protein 11 Myosin_tail_1 PF01576.14 KZN93106.1 - 5.8e-07 27.6 22.7 5.8e-07 27.6 15.7 5.1 5 0 0 5 5 5 1 Myosin tail APG17 PF04108.7 KZN93106.1 - 6.1e-06 25.2 0.5 6.1e-06 25.2 0.3 5.9 4 3 1 6 6 6 2 Autophagy protein Apg17 GAS PF13851.1 KZN93106.1 - 0.00091 18.4 15.6 0.00091 18.4 10.8 6.3 5 2 1 7 7 7 1 Growth-arrest specific micro-tubule binding Ssu72 PF04722.8 KZN93106.1 - 0.16 11.3 1.7 0.39 9.9 1.2 1.7 1 0 0 1 1 1 0 Ssu72-like protein Fib_alpha PF08702.5 KZN93106.1 - 5.8 7.0 41.6 0.8 9.8 4.5 7.0 6 2 2 8 8 8 0 Fibrinogen alpha/beta chain family Abhydrolase_3 PF07859.8 KZN93109.1 - 1.9e-39 135.4 0.0 1.3e-37 129.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KZN93109.1 - 1.4e-07 30.4 0.0 5.7e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KZN93109.1 - 0.045 13.5 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HATPase_c PF02518.21 KZN93110.1 - 5.3e-30 103.4 0.0 2.5e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN93110.1 - 5.4e-21 74.6 0.2 3e-20 72.2 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KZN93110.1 - 4.1e-19 68.3 0.0 1.5e-18 66.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 KZN93110.1 - 4.8e-12 46.5 0.0 1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 KZN93110.1 - 6.2e-12 45.8 1.8 1.7e-10 41.1 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain GAF_3 PF13492.1 KZN93110.1 - 2.5e-09 37.3 0.1 1.7e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 KZN93110.1 - 2.5e-06 26.8 0.0 9.9e-06 24.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.21 KZN93110.1 - 4.7e-05 23.5 0.0 0.00031 20.8 0.0 2.3 2 0 0 2 2 2 1 GAF domain NACHT PF05729.7 KZN93110.1 - 0.0027 17.3 0.0 0.51 9.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_35 PF14516.1 KZN93110.1 - 0.0029 16.2 0.0 0.4 9.2 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain NB-ARC PF00931.17 KZN93110.1 - 0.0051 15.7 0.2 2.8 6.7 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain HATPase_c_3 PF13589.1 KZN93110.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 KZN93110.1 - 0.038 14.1 0.1 3.2 7.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.19 KZN93112.1 - 2.6e-59 201.0 28.0 3.1e-59 200.7 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93112.1 - 1.4e-25 89.8 27.4 1.8e-25 89.4 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 KZN93113.1 - 2.4e-63 214.0 0.0 3.1e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF608 PF04685.8 KZN93113.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Glyco_hydro_1 PF00232.13 KZN93114.1 - 5.1e-147 489.7 1.2 7e-147 489.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AAT PF03417.11 KZN93114.1 - 1.3e-20 73.8 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KZN93114.1 - 0.00029 21.1 0.0 0.00068 19.9 0.0 1.7 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Cytochrom_B561 PF03188.11 KZN93116.1 - 8.6e-16 58.0 5.3 8.6e-16 58.0 3.7 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF1129 PF06570.6 KZN93116.1 - 0.025 13.8 5.4 0.041 13.1 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2427 PF10348.4 KZN93116.1 - 0.42 10.2 9.6 0.033 13.7 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) tRNA-synt_2b PF00587.20 KZN93117.1 - 2.1e-21 76.2 0.0 3.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KZN93117.1 - 4.7e-09 36.2 2.6 2.1e-08 34.1 1.8 1.9 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 KZN93117.1 - 1.4e-05 23.8 1.0 1.9e-05 23.3 0.7 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 CENP-F_leu_zip PF10473.4 KZN93117.1 - 0.0012 18.6 2.2 0.4 10.5 0.0 2.3 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 KZN93117.1 - 0.0062 15.9 1.5 0.67 9.4 0.1 2.4 2 0 0 2 2 2 1 Septum formation initiator DUF904 PF06005.7 KZN93117.1 - 0.011 16.0 0.7 0.8 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4407 PF14362.1 KZN93117.1 - 0.02 13.8 1.2 0.044 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.3 KZN93117.1 - 0.029 14.0 0.3 6.6 6.4 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KZN93117.1 - 0.039 13.5 2.9 0.069 12.7 2.0 1.3 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 KZN93117.1 - 0.077 13.0 4.1 0.15 12.0 2.8 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Striatin PF08232.7 KZN93117.1 - 0.086 13.1 3.0 0.21 11.9 2.0 1.6 1 0 0 1 1 1 0 Striatin family TMCO5 PF14992.1 KZN93117.1 - 0.11 11.6 2.7 0.17 11.0 1.9 1.2 1 0 0 1 1 1 0 TMCO5 family Mnd1 PF03962.10 KZN93117.1 - 0.14 11.7 3.9 0.29 10.7 2.7 1.4 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KZN93117.1 - 0.23 11.9 1.9 9.3 6.7 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 KZN93117.1 - 0.54 9.7 6.9 3.4 7.1 0.9 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 KZN93117.1 - 0.64 8.3 1.6 0.94 7.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BTB PF00651.26 KZN93118.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Y_phosphatase PF00102.22 KZN93119.1 - 1.4e-52 178.3 0.0 3.7e-52 177.0 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KZN93119.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KZN93119.1 - 0.0024 17.9 0.0 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KZN93119.1 - 0.027 14.0 0.6 0.079 12.5 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain VanZ PF04892.7 KZN93120.1 - 5.7e-12 45.7 2.2 8.2e-12 45.2 1.5 1.2 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KZN93120.1 - 0.0009 18.3 0.1 0.0011 18.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) Antimicrobial20 PF08256.6 KZN93120.1 - 0.13 12.6 0.1 0.32 11.4 0.1 1.7 1 0 0 1 1 1 0 Aurein-like antibiotic peptide DUF4383 PF14325.1 KZN93120.1 - 0.15 12.0 2.3 0.43 10.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) DUF4131 PF13567.1 KZN93120.1 - 5.2 6.4 5.6 15 4.9 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 KZN93121.1 - 2e-17 62.9 0.0 5.5e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KZN93121.1 - 2.6e-10 39.8 0.0 9.3e-10 38.1 0.0 2.0 1 0 0 1 1 1 1 Bromodomain associated HisKA_3 PF07730.8 KZN93121.1 - 0.24 11.7 4.1 2 8.7 0.0 3.3 3 0 0 3 3 3 0 Histidine kinase Piwi PF02171.12 KZN93122.1 - 2.2e-58 197.5 0.0 3.7e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KZN93122.1 - 4.2e-14 52.0 0.8 8.4e-14 51.0 0.6 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KZN93122.1 - 1.3e-09 37.2 0.0 2.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) TraT PF05818.7 KZN93122.1 - 0.21 10.9 0.1 2.4 7.5 0.0 2.4 2 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein Ima1_N PF09779.4 KZN93123.1 - 0.022 15.2 3.1 0.033 14.6 2.2 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain MRP-S32 PF10210.4 KZN93123.1 - 0.028 14.7 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Coat_F PF07875.7 KZN93123.1 - 0.029 14.5 0.1 0.082 13.0 0.1 1.7 2 0 0 2 2 2 0 Coat F domain Glu_syn_central PF04898.9 KZN93123.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain CHORD PF04968.7 KZN93123.1 - 0.15 12.3 0.4 0.15 12.3 0.3 2.3 2 1 0 2 2 2 0 CHORD Cut8_M PF14483.1 KZN93123.1 - 0.15 11.8 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Cut8 dimerisation domain NinF PF05810.7 KZN93123.1 - 0.24 11.2 2.1 0.36 10.6 0.2 2.2 1 1 1 2 2 2 0 NinF protein Suf PF05843.9 KZN93124.1 - 2e-87 293.4 0.0 2e-87 293.4 0.0 3.8 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KZN93124.1 - 0.0001 22.6 2.6 0.032 14.8 0.3 5.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN93124.1 - 0.00012 22.6 4.4 0.011 16.4 0.1 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 KZN93124.1 - 0.021 14.5 0.0 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DUF4063 PF13272.1 KZN93124.1 - 0.23 11.2 0.3 1.1 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) ASF1_hist_chap PF04729.8 KZN93125.1 - 2.5e-66 222.0 0.0 3.5e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KZN93125.1 - 0.078 10.8 24.6 0.11 10.4 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.5 KZN93126.1 - 9.2e-133 442.5 0.0 9.9e-132 439.1 0.0 2.2 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KZN93126.1 - 8.4e-06 25.4 2.2 0.26 11.2 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 KZN93126.1 - 0.027 12.6 0.0 0.27 9.3 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.18 KZN93127.1 - 9.7e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 KZN93128.1 - 7.5e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.7 KZN93128.1 - 0.071 12.8 0.9 0.096 12.3 0.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPP_enzyme_N PF02776.13 KZN93129.1 - 1.7e-36 125.2 0.0 2.5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN93129.1 - 4.5e-26 91.2 0.0 8.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KZN93129.1 - 6e-16 58.3 0.0 1.8e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KZN93129.1 - 0.028 13.1 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Pkinase PF00069.20 KZN93130.1 - 3.7e-62 209.8 0.0 5.5e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93130.1 - 3.3e-43 147.6 0.0 4.8e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN93130.1 - 9.3e-08 31.3 0.0 2.8e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KZN93130.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 KZN93131.1 - 7.2e-28 97.2 2.8 1.8e-27 95.9 1.9 1.7 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.10 KZN93131.1 - 0.0069 15.2 2.5 1.3 7.7 0.1 3.1 3 0 0 3 3 3 2 Exo70 exocyst complex subunit GAS PF13851.1 KZN93131.1 - 0.045 12.9 1.6 0.11 11.6 0.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2127 PF09900.4 KZN93131.1 - 0.11 12.5 0.1 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) RCC1 PF00415.13 KZN93132.1 - 1.1e-30 105.5 2.7 3.7e-05 23.8 0.0 7.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KZN93132.1 - 1.9e-19 68.7 11.6 2.4e-12 46.1 0.1 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PUF PF00806.14 KZN93133.1 - 9.8e-14 49.9 0.0 0.21 11.1 0.0 7.6 9 0 0 9 9 9 5 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.14 KZN93134.1 - 1.9e-80 270.1 0.0 3.9e-79 265.8 0.0 2.4 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KZN93134.1 - 7.7e-06 24.8 0.0 1.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KZN93134.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KZN93134.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RINT1_TIP1 PF04437.8 KZN93135.1 - 1.9e-185 617.1 0.1 1.9e-185 617.1 0.1 2.2 2 1 1 3 3 3 1 RINT-1 / TIP-1 family ACT_6 PF13740.1 KZN93135.1 - 0.076 12.7 0.0 0.35 10.6 0.0 2.2 1 0 0 1 1 1 0 ACT domain DUF45 PF01863.12 KZN93135.1 - 1.1 8.9 4.1 0.52 10.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF45 DNA_ligase_A_M PF01068.16 KZN93136.1 - 5.9e-51 172.7 0.1 3.9e-48 163.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KZN93136.1 - 1.1e-43 149.0 0.2 4e-43 147.2 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KZN93136.1 - 8.2e-19 67.8 0.0 3e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DUF1365 PF07103.6 KZN93137.1 - 3.5e-11 42.6 0.0 1.3e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) Pyr_redox_3 PF13738.1 KZN93138.1 - 5.7e-24 85.3 0.0 1.9e-23 83.6 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN93138.1 - 1.4e-10 40.9 0.0 3.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN93138.1 - 1.9e-08 34.4 0.0 5.6e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN93138.1 - 4e-08 31.9 0.1 1.1e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KZN93138.1 - 3.2e-06 26.2 0.0 7.3e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN93138.1 - 5.4e-06 26.2 0.0 0.00024 20.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KZN93138.1 - 0.00011 21.2 0.0 0.0006 18.8 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN93138.1 - 0.00013 21.1 0.0 0.0032 16.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 KZN93138.1 - 0.0039 17.2 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KZN93138.1 - 0.012 15.9 0.0 0.053 13.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN93138.1 - 0.14 10.9 0.0 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Metallopep PF12044.3 KZN93140.1 - 2.8e-176 586.1 0.0 3.4e-176 585.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KZN93140.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KZN93140.1 - 0.026 14.4 0.4 0.048 13.5 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 CP2 PF04516.10 KZN93141.1 - 1.1e-82 276.6 0.0 1.8e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Clathrin PF00637.15 KZN93143.1 - 3.8e-19 68.6 0.1 2e-18 66.3 0.1 2.1 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 KZN93143.1 - 0.00014 21.6 1.0 0.075 12.9 0.3 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 KZN93143.1 - 0.047 13.4 0.2 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_1 PF10366.4 KZN93143.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 PQQ_3 PF13570.1 KZN93143.1 - 0.31 11.3 2.3 0.77 10.1 0.1 2.8 3 0 0 3 3 3 0 PQQ-like domain DNA_pol_phi PF04931.8 KZN93143.1 - 9.3 3.8 8.9 14 3.2 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF155 PF02582.9 KZN93144.1 - 2.5e-43 148.0 0.0 4.6e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.13 KZN93145.1 - 4e-46 157.0 0.0 6.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family zf-H2C2_2 PF13465.1 KZN93146.1 - 1.5e-10 40.8 4.2 0.00013 22.0 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KZN93146.1 - 1.8e-05 24.7 22.0 0.00087 19.4 2.9 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KZN93146.1 - 0.0011 19.0 5.3 0.0033 17.5 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KZN93146.1 - 0.0032 17.6 17.2 0.018 15.3 1.3 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger Bunya_G2 PF03563.8 KZN93146.1 - 0.21 10.4 0.5 0.37 9.6 0.4 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 KZN93146.1 - 0.21 11.5 6.4 0.65 9.9 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 KZN93146.1 - 0.54 10.0 8.6 0.13 12.0 2.7 2.2 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.2 KZN93146.1 - 8.7 6.7 6.7 1.8 8.8 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ubiquitin PF00240.18 KZN93147.1 - 1.5e-34 117.2 0.9 2.8e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KZN93147.1 - 5.1e-28 96.6 1.9 9.3e-28 95.7 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KZN93147.1 - 6.1e-20 70.6 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KZN93147.1 - 1e-05 25.7 0.4 4e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KZN93147.1 - 0.00012 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KZN93147.1 - 0.0012 18.6 0.6 0.0026 17.6 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KZN93147.1 - 0.0042 17.2 0.4 0.0057 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 KZN93147.1 - 0.018 14.8 0.4 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 KZN93147.1 - 0.06 13.3 0.6 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KZN93147.1 - 0.16 10.2 2.3 4.9 5.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 KZN93148.1 - 3.1e-97 326.1 0.5 3.6e-97 325.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3293 PF11697.3 KZN93149.1 - 0.063 13.4 0.2 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Acyl-CoA_dh_1 PF00441.19 KZN93149.1 - 0.13 12.3 2.1 0.095 12.7 0.7 1.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Proteasome PF00227.21 KZN93150.1 - 2.1e-50 170.6 0.1 2.9e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KZN93150.1 - 5.6e-13 47.9 0.3 8.9e-13 47.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 KZN93150.1 - 0.34 10.4 3.6 0.17 11.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 KZN93151.1 - 9.5e-21 73.1 0.2 1.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Spc97_Spc98 PF04130.8 KZN93152.1 - 2.6e-123 412.2 0.0 3.8e-123 411.6 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Fringe PF02434.11 KZN93153.1 - 4.3e-08 32.6 0.0 9e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KZN93153.1 - 0.00019 21.1 0.5 0.0007 19.2 0.3 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KZN93153.1 - 0.00082 19.0 0.1 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 KZN93153.1 - 0.013 15.3 0.3 0.035 13.9 0.2 1.7 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.16 KZN93153.1 - 0.014 15.0 0.0 0.48 9.9 0.0 2.3 1 1 0 2 2 2 0 Galactosyltransferase Aft1_HRA PF11786.3 KZN93154.1 - 8.6e-29 99.6 11.9 8.6e-29 99.6 8.3 2.9 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.3 KZN93154.1 - 1.4e-20 73.5 10.3 1.4e-20 73.5 7.1 3.9 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.3 KZN93154.1 - 5.1e-20 72.2 6.7 5.1e-20 72.2 4.6 4.1 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 KZN93154.1 - 2.2e-13 49.9 5.2 4.3e-13 49.0 3.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KZN93154.1 - 5.5e-06 26.1 6.5 1.3e-05 24.9 4.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KZN93154.1 - 0.0075 16.5 4.3 0.0075 16.5 3.0 2.5 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF4554 PF15091.1 KZN93154.1 - 0.87 8.2 5.4 1.5 7.4 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) AvrE PF11725.3 KZN93154.1 - 2.3 5.1 19.4 2.9 4.7 13.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor Macoilin PF09726.4 KZN93154.1 - 9.1 4.4 16.0 13 3.9 11.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Transthyretin PF00576.16 KZN93155.1 - 1.5e-21 76.3 0.0 8.7e-20 70.6 0.0 2.1 1 1 0 1 1 1 1 HIUase/Transthyretin family phage_tail_N PF08400.5 KZN93155.1 - 0.049 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal ArsA_ATPase PF02374.10 KZN93156.1 - 5.9e-115 383.4 0.1 6.8e-115 383.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KZN93156.1 - 2.1e-17 63.1 0.3 3.5e-17 62.4 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KZN93156.1 - 1.9e-08 34.4 0.0 2.4e-07 30.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KZN93156.1 - 1.5e-06 27.6 0.1 3.8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KZN93156.1 - 1.8e-05 24.2 0.3 0.00067 19.1 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KZN93156.1 - 0.0082 15.5 0.3 0.025 13.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN93156.1 - 0.011 15.5 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 KZN93156.1 - 0.012 14.9 0.1 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein MipZ PF09140.6 KZN93156.1 - 0.013 14.5 0.1 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 KZN93156.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KZN93156.1 - 0.027 13.8 0.0 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein T2SE PF00437.15 KZN93156.1 - 0.076 11.9 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 KZN93156.1 - 0.087 11.6 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AIP3 PF03915.8 KZN93156.1 - 0.088 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 A1_Propeptide PF07966.7 KZN93156.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.4 3 0 0 3 3 3 0 A1 Propeptide eIF3_N PF09440.5 KZN93158.1 - 2.5e-51 173.3 3.2 2.9e-51 173.1 1.5 1.7 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KZN93158.1 - 9.3e-14 51.6 0.0 3e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain EF_assoc_1 PF08355.7 KZN93158.1 - 0.0097 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 EF hand associated PCI_Csn8 PF10075.4 KZN93158.1 - 0.022 14.5 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Cortex-I_coil PF09304.5 KZN93158.1 - 0.19 11.7 2.5 0.56 10.2 1.4 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Img2 PF05046.9 KZN93159.1 - 3.2e-26 91.3 0.0 5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 KZN93160.1 - 1.4e-19 69.6 0.0 4e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 KZN93161.1 - 1.7e-46 157.6 0.1 6e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KZN93161.1 - 3.2e-09 36.6 0.6 1.1e-08 34.9 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN93161.1 - 4.2e-09 36.5 0.0 8.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KZN93161.1 - 2e-07 31.2 0.0 6.6e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KZN93161.1 - 2.3e-06 27.7 2.3 0.00011 22.3 0.5 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KZN93161.1 - 1.7e-05 24.6 0.0 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KZN93161.1 - 5.4e-05 22.2 0.0 0.0001 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KZN93161.1 - 0.00022 22.0 0.1 0.0012 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KZN93161.1 - 0.00046 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KZN93161.1 - 0.00065 19.4 0.9 0.056 13.0 0.0 3.2 3 1 0 3 3 3 1 NACHT domain NTPase_1 PF03266.10 KZN93161.1 - 0.00067 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 KZN93161.1 - 0.00073 18.6 0.1 0.0019 17.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KZN93161.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN93161.1 - 0.0012 18.5 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KZN93161.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KZN93161.1 - 0.002 16.8 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 KZN93161.1 - 0.0023 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KZN93161.1 - 0.0032 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KZN93161.1 - 0.0042 17.4 0.2 0.47 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KZN93161.1 - 0.0043 16.6 0.2 0.019 14.5 0.0 2.0 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.21 KZN93161.1 - 0.0049 16.3 0.1 0.2 11.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KZN93161.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KZN93161.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KZN93161.1 - 0.011 15.1 0.4 0.031 13.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KZN93161.1 - 0.012 15.2 1.1 0.13 11.9 0.0 2.5 2 1 0 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 KZN93161.1 - 0.014 14.9 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KZN93161.1 - 0.015 14.6 2.6 0.066 12.6 0.1 2.5 2 1 0 3 3 3 0 AAA domain Bac_DnaA PF00308.13 KZN93161.1 - 0.027 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 KZN93161.1 - 0.028 14.7 0.0 0.086 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cast PF10174.4 KZN93161.1 - 0.029 12.4 1.0 0.056 11.4 0.4 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AAA_30 PF13604.1 KZN93161.1 - 0.043 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KZN93161.1 - 0.058 12.5 0.9 0.75 8.8 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 KZN93161.1 - 0.079 13.0 0.0 0.4 10.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KZN93161.1 - 0.12 12.6 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KZN93161.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_Hsp90 PF03225.9 KZN93161.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 KZN93161.1 - 0.16 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 KZN93162.1 - 2.5e-109 365.3 0.0 3e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KZN93162.1 - 3.9e-12 46.4 0.1 1.1e-11 45.0 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KZN93162.1 - 1.4e-06 28.6 0.2 0.019 15.4 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KZN93162.1 - 6e-05 22.6 0.0 0.00092 18.7 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal NIF PF03031.13 KZN93163.1 - 1.2e-29 103.0 0.0 2.5e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KZN93163.1 - 5.6e-10 38.9 0.1 1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KZN93163.1 - 4.5e-08 33.1 0.0 1.4e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 KZN93163.1 - 0.035 13.7 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme MARVEL PF01284.18 KZN93164.1 - 0.0038 17.0 15.7 0.0057 16.4 10.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.7 KZN93164.1 - 3 8.0 14.9 0.21 11.7 6.2 2.1 2 1 0 2 2 2 0 Papillomavirus E5A protein Arginase PF00491.16 KZN93165.1 - 6.7e-79 265.0 0.7 7.7e-79 264.8 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 KZN93166.1 - 8.6e-102 339.8 0.0 1.2e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KZN93166.1 - 3.1e-26 91.8 0.0 6.4e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 GatB domain Vitellogenin_N PF01347.17 KZN93166.1 - 0.076 11.2 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region UNC-93 PF05978.11 KZN93167.1 - 3.2e-10 39.7 3.0 3.2e-10 39.7 2.1 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KZN93167.1 - 3.2e-08 32.6 30.7 3.2e-08 32.6 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93167.1 - 0.002 16.7 22.9 0.0054 15.3 13.6 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DAO PF01266.19 KZN93168.1 - 1.7e-55 188.4 0.0 1.9e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN93168.1 - 0.00047 20.0 0.0 0.17 11.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN93168.1 - 0.013 15.2 0.2 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KZN93168.1 - 0.019 13.8 0.0 0.57 8.9 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KZN93168.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ldh_1_N PF00056.18 KZN93168.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN93168.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.9 KZN93168.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DGC PF08859.6 KZN93169.1 - 0.39 10.6 4.4 0.2 11.5 1.3 1.8 1 1 0 1 1 1 0 DGC domain DUF1005 PF06219.7 KZN93169.1 - 1.3 7.6 7.1 0.43 9.2 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1005) Dioxygenase_C PF00775.16 KZN93170.1 - 5e-08 32.4 0.0 9.1e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Pox_T4_N PF04491.7 KZN93170.1 - 0.025 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus YL1 PF05764.8 KZN93172.1 - 0.005 16.4 0.3 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Bromodomain PF00439.20 KZN93173.1 - 0.092 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Bromodomain PPR_3 PF13812.1 KZN93174.1 - 0.00036 20.5 2.0 14 6.2 0.1 5.2 5 0 0 5 5 5 2 Pentatricopeptide repeat domain ECH PF00378.15 KZN93175.1 - 3e-50 170.6 0.0 3.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family LmjF365940-deam PF14421.1 KZN93175.1 - 0.08 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases NB-ARC PF00931.17 KZN93176.1 - 6.3e-13 48.2 0.0 9.4e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KZN93176.1 - 1.3e-06 28.4 0.0 3.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KZN93176.1 - 1.6e-05 24.9 0.1 3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KZN93176.1 - 4.1e-05 23.7 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KZN93176.1 - 0.00015 21.4 0.1 0.00093 18.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KZN93176.1 - 0.00055 19.1 0.1 0.0036 16.4 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin DUF676 PF05057.9 KZN93176.1 - 0.00059 19.1 0.4 0.0024 17.1 0.3 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) KaiC PF06745.8 KZN93176.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 KZN93176.1 - 0.023 14.5 0.1 0.073 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN93176.1 - 0.025 15.4 0.0 0.068 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KZN93176.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 KZN93176.1 - 0.055 13.2 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 KZN93176.1 - 0.089 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PGAP1 PF07819.8 KZN93176.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_10 PF12846.2 KZN93176.1 - 0.094 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RuvB_N PF05496.7 KZN93176.1 - 0.096 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ADH_zinc_N_2 PF13602.1 KZN93177.1 - 2.7e-21 76.7 0.0 4.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN93177.1 - 4.3e-17 61.8 0.0 7.6e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KZN93177.1 - 0.0024 17.4 0.6 0.0038 16.8 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Peptidase_S41 PF03572.13 KZN93177.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 Transp_cyt_pur PF02133.10 KZN93179.1 - 7.6e-102 341.1 29.5 8.9e-102 340.8 20.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 KZN93180.1 - 7.4e-27 94.1 0.1 1.2e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN93180.1 - 3.4e-20 72.1 0.0 7.3e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 KZN93180.1 - 0.13 11.7 0.1 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 KZN93182.1 - 8.5e-43 146.4 59.3 1.1e-42 146.0 37.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN93182.1 - 8.9e-13 47.2 27.3 1.2e-12 46.8 18.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2217 PF10265.4 KZN93183.1 - 0.092 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF883 PF05957.8 KZN93183.1 - 0.12 12.7 6.6 0.53 10.7 1.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KZN93183.1 - 0.69 10.3 12.5 0.32 11.3 3.8 2.3 1 1 1 2 2 2 0 YtxH-like protein ATP-synt_B PF00430.13 KZN93183.1 - 1.6 8.5 6.4 2.4 7.9 4.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) FHA PF00498.21 KZN93184.1 - 1.5e-13 50.6 0.0 3.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.26 KZN93185.1 - 4.5e-11 42.3 1.1 8.7e-11 41.3 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain HATPase_c PF02518.21 KZN93186.1 - 4.5e-22 77.8 0.0 1.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN93186.1 - 6.6e-21 74.4 0.3 3.5e-20 72.0 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KZN93186.1 - 5.2e-18 64.8 2.2 1.8e-17 63.0 0.0 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KZN93186.1 - 4e-11 43.2 0.1 7.4e-07 29.5 0.0 3.3 3 1 0 3 3 3 2 PAS domain PAS_3 PF08447.6 KZN93186.1 - 5.4e-10 39.2 4.4 0.011 15.7 0.2 3.9 2 1 1 3 3 3 3 PAS fold PAS_4 PF08448.5 KZN93186.1 - 2.7e-06 27.3 0.1 5.3e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 KZN93186.1 - 0.00086 19.0 0.0 2 8.2 0.0 3.0 2 0 0 2 2 2 2 PAS fold MotA_ExbB PF01618.11 KZN93186.1 - 0.3 10.6 0.0 1 8.9 0.0 1.9 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family KxDL PF10241.4 KZN93187.1 - 2.7e-34 116.9 1.0 3.4e-34 116.5 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF883 PF05957.8 KZN93187.1 - 0.84 10.0 4.1 1.5 9.2 2.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AAA PF00004.24 KZN93188.1 - 1e-53 181.0 0.0 2.5e-39 134.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KZN93188.1 - 1.4e-13 50.5 0.0 3.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KZN93188.1 - 5.1e-12 45.2 0.1 1.1e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KZN93188.1 - 2.4e-08 34.2 0.1 0.00054 20.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KZN93188.1 - 2.5e-08 33.8 0.0 0.0038 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KZN93188.1 - 2.2e-07 30.5 0.5 0.016 14.9 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_16 PF13191.1 KZN93188.1 - 4.9e-07 29.9 0.1 0.0061 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 KZN93188.1 - 1.5e-06 28.2 0.0 9.7e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KZN93188.1 - 1.8e-06 27.2 0.1 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KZN93188.1 - 1.9e-06 28.6 0.1 0.013 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KZN93188.1 - 3e-06 26.2 0.1 0.021 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 KZN93188.1 - 3.2e-06 26.3 0.1 0.07 12.1 0.1 2.7 3 1 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KZN93188.1 - 3.4e-06 26.8 0.0 0.00091 18.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KZN93188.1 - 3.7e-06 26.8 0.0 0.057 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KZN93188.1 - 2.6e-05 24.5 0.0 0.026 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KZN93188.1 - 0.00027 20.9 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KZN93188.1 - 0.00029 20.6 0.6 8.1 6.0 0.1 4.1 3 1 1 4 4 4 0 Archaeal ATPase AAA_25 PF13481.1 KZN93188.1 - 0.0003 20.2 1.4 0.62 9.4 0.0 3.9 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.17 KZN93188.1 - 0.00032 20.8 0.0 0.054 13.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 KZN93188.1 - 0.00047 19.6 0.6 0.054 12.9 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KZN93188.1 - 0.0009 18.3 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 KZN93188.1 - 0.0011 18.6 1.8 0.15 11.6 0.1 3.4 3 1 0 3 3 3 1 AAA domain KTI12 PF08433.5 KZN93188.1 - 0.0043 16.3 0.1 1.6 7.8 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 KaiC PF06745.8 KZN93188.1 - 0.0047 16.0 0.2 0.066 12.3 0.1 2.3 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.12 KZN93188.1 - 0.0048 15.8 0.0 0.77 8.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KZN93188.1 - 0.0075 16.5 0.2 0.047 13.9 0.1 2.3 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 KZN93188.1 - 0.0091 15.6 0.2 6.3 6.4 0.0 2.8 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.21 KZN93188.1 - 0.027 13.9 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KZN93188.1 - 0.028 14.0 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KZN93188.1 - 0.029 13.2 0.1 1.7 7.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.1 KZN93188.1 - 0.035 13.6 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KZN93188.1 - 0.04 13.1 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 KZN93188.1 - 0.053 13.1 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KZN93188.1 - 0.087 12.3 0.0 2 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KZN93188.1 - 0.094 12.2 0.0 0.27 10.6 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 KZN93188.1 - 0.15 12.1 0.0 7.4 6.6 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 KZN93188.1 - 0.16 10.9 0.1 0.42 9.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Methyltransf_31 PF13847.1 KZN93190.1 - 3.6e-11 42.8 0.0 7.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KZN93190.1 - 1.7e-09 37.2 0.2 3.3e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KZN93190.1 - 6.4e-09 36.3 0.0 2.4e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93190.1 - 1.7e-08 34.8 0.0 4.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN93190.1 - 1.3e-07 31.6 0.0 3.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN93190.1 - 9.9e-07 28.2 0.2 2.2e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KZN93190.1 - 1.8e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93190.1 - 3.2e-05 24.2 0.0 8.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KZN93190.1 - 0.00088 18.0 0.0 0.0017 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 KZN93190.1 - 0.0018 17.4 0.1 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 KZN93190.1 - 0.0025 18.2 0.0 0.0062 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KZN93190.1 - 0.0043 16.6 0.3 0.0075 15.8 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 KZN93190.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.11 KZN93190.1 - 0.008 15.1 0.0 0.018 13.9 0.0 1.7 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 KZN93190.1 - 0.013 14.5 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Surfac_D-trimer PF09006.6 KZN93190.1 - 0.023 14.4 0.4 0.24 11.1 0.3 2.6 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation Methyltransf_16 PF10294.4 KZN93190.1 - 0.027 13.9 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 KZN93190.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KZN93190.1 - 0.047 12.7 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 KZN93190.1 - 0.074 13.8 0.0 0.25 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KZN93190.1 - 0.17 11.4 0.1 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Mo25 PF08569.6 KZN93191.1 - 9.1e-127 422.6 0.6 1e-126 422.5 0.4 1.0 1 0 0 1 1 1 1 Mo25-like RabGAP-TBC PF00566.13 KZN93192.1 - 2.4e-32 112.1 0.0 3.6e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 3HCDH_N PF02737.13 KZN93193.1 - 9.9e-33 113.2 0.0 1.7e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KZN93193.1 - 1.3e-15 57.5 0.1 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KZN93193.1 - 1.6e-06 27.9 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KZN93193.1 - 3.2e-05 23.8 0.2 8.5e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN93193.1 - 0.00051 20.4 0.7 0.002 18.5 0.4 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KZN93193.1 - 0.032 13.1 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.11 KZN93194.1 - 3.7e-41 141.0 29.5 5.5e-41 140.4 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN93194.1 - 0.001 18.8 2.0 0.0031 17.2 1.4 1.9 1 0 0 1 1 1 1 MFS_1 like family Acyl_transf_3 PF01757.17 KZN93194.1 - 0.031 13.1 28.5 0.031 13.1 9.0 2.4 2 0 0 2 2 2 0 Acyltransferase family Phage_holin_5 PF06946.6 KZN93194.1 - 0.096 12.8 0.1 0.096 12.8 0.1 2.6 3 0 0 3 3 3 0 Phage holin OSTbeta PF15048.1 KZN93194.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Cg6151-P PF10233.4 KZN93195.1 - 2.1e-37 127.5 12.3 2.5e-37 127.2 8.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PEMT PF04191.8 KZN93195.1 - 0.0072 16.4 9.6 0.22 11.6 0.4 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase CbiQ PF02361.11 KZN93195.1 - 0.87 9.1 11.1 1.1 8.7 7.7 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF4149 PF13664.1 KZN93195.1 - 2.1 8.4 8.6 0.82 9.7 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) EmrE PF13536.1 KZN93195.1 - 2.5 8.3 12.7 0.13 12.5 2.3 2.1 1 1 1 2 2 2 0 Multidrug resistance efflux transporter DUF3210 PF11489.3 KZN93196.1 - 6.7e-240 798.5 85.2 6.7e-240 798.5 59.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3210) FANCL_C PF11793.3 KZN93197.1 - 1.1e-06 28.5 2.8 2e-06 27.6 1.9 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KZN93197.1 - 8.8e-06 25.6 5.9 1.6e-05 24.8 4.1 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN93197.1 - 0.0008 19.1 4.6 0.0014 18.4 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain MRP-L28 PF09812.4 KZN93198.1 - 6.4e-09 35.8 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 NST1 PF13945.1 KZN93199.1 - 8.9e-66 221.5 0.1 8.9e-66 221.5 0.1 4.5 2 2 2 4 4 4 1 Salt tolerance down-regulator Vps35 PF03635.12 KZN93200.1 - 0 1036.4 0.2 0 1036.2 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 zf-C3HC4_3 PF13920.1 KZN93201.1 - 0.94 9.2 3.9 16 5.2 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AAA_12 PF13087.1 KZN93202.1 - 1.7e-38 132.0 0.0 3.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN93202.1 - 5.1e-28 98.2 0.1 9.8e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN93202.1 - 6.3e-11 41.8 0.1 7e-10 38.5 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain UvrD-helicase PF00580.16 KZN93202.1 - 0.0001 21.7 0.0 0.00025 20.4 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 KZN93202.1 - 0.00054 19.6 0.3 0.01 15.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KZN93202.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KZN93202.1 - 0.0099 14.8 0.1 0.064 12.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.19 KZN93202.1 - 0.016 14.9 2.9 0.11 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UvrD_C_2 PF13538.1 KZN93202.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Apo-CII PF05355.6 KZN93202.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein C-II TPP_enzyme_N PF02776.13 KZN93203.1 - 4.5e-58 195.5 0.0 1.5e-57 193.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KZN93203.1 - 5.7e-48 162.3 0.0 9.9e-47 158.3 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN93203.1 - 7.1e-36 122.9 0.1 1.5e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KZN93203.1 - 0.03 13.8 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.4 KZN93204.1 - 1.3e-19 69.1 0.0 2.8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KZN93204.1 - 3.3e-15 55.8 2.0 6.7e-15 54.9 0.6 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KZN93204.1 - 2.6e-12 46.7 0.0 5.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal RNase_H2-Ydr279 PF09468.5 KZN93205.1 - 7.6e-87 291.3 0.3 9.6e-87 290.9 0.2 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Glu-tRNAGln PF02686.10 KZN93205.1 - 0.02 14.6 1.4 6.3 6.6 0.1 3.6 4 0 0 4 4 4 0 Glu-tRNAGln amidotransferase C subunit Alpha_GJ PF03229.8 KZN93205.1 - 2.5 8.4 5.1 5.7 7.3 3.5 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J zf-primase PF09329.6 KZN93206.1 - 1.2e-18 66.4 1.5 2e-18 65.6 1.0 1.4 1 0 0 1 1 1 1 Primase zinc finger Tic20 PF09685.5 KZN93208.1 - 1.4e-07 31.4 1.9 1.8e-07 31.1 1.3 1.2 1 0 0 1 1 1 1 Tic20-like protein PP2C PF00481.16 KZN93209.1 - 1.2e-41 142.8 0.0 2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KZN93209.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KZN93209.1 - 0.04 13.6 0.0 12 5.5 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) FCH PF00611.18 KZN93210.1 - 2.7e-19 69.1 1.4 5.2e-19 68.2 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KZN93210.1 - 1.9e-13 49.5 0.0 3.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KZN93210.1 - 1.7e-11 43.4 0.0 5.2e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KZN93210.1 - 1.1e-10 40.9 0.0 2.3e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Streptin-Immun PF11083.3 KZN93210.1 - 0.14 12.2 1.7 0.78 9.7 0.2 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein WD40 PF00400.27 KZN93212.1 - 0.047 13.5 6.8 36 4.4 1.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 KZN93213.1 - 1.9e-16 60.6 1.5 2.3e-16 60.3 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93213.1 - 4.3e-09 36.2 0.0 7.9e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN93213.1 - 8e-07 28.8 0.8 2.6e-06 27.1 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.7 KZN93213.1 - 0.028 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 KZN93213.1 - 0.031 13.5 0.3 0.09 11.9 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1749 PF08538.5 KZN93214.1 - 1.4e-103 345.9 0.0 1.7e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KZN93214.1 - 5.1e-06 26.5 0.1 1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93214.1 - 4.6e-05 23.2 0.0 0.00012 21.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KZN93214.1 - 0.014 14.8 0.0 1.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Glycos_transf_2 PF00535.21 KZN93215.1 - 3.1e-36 124.6 0.0 3.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KZN93215.1 - 5.6e-15 55.7 0.0 8.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KZN93215.1 - 3.7e-10 39.3 0.0 6.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KZN93215.1 - 0.00016 21.0 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KZN93215.1 - 0.007 16.1 2.2 0.0089 15.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 KZN93215.1 - 0.043 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 TPR_19 PF14559.1 KZN93216.1 - 3.9e-08 33.5 1.5 0.011 16.1 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN93216.1 - 9e-08 32.5 0.0 0.0013 19.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN93216.1 - 0.00017 21.4 0.4 0.2 11.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93216.1 - 0.00062 20.1 3.2 4 8.3 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KZN93216.1 - 0.0024 17.4 0.0 0.65 9.6 0.0 2.8 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KZN93216.1 - 0.0092 15.8 0.2 8.5 6.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KZN93216.1 - 0.085 12.7 2.8 0.61 10.0 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN93216.1 - 0.089 13.2 7.6 8.1 7.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KZN93216.1 - 0.1 13.1 0.3 88 3.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KZN93216.1 - 0.1 12.8 1.0 6.6 7.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KZN93216.1 - 0.35 10.8 3.5 2.4 8.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 KZN93217.1 - 3.1e-09 36.7 0.1 5.1e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KZN93217.1 - 0.0018 18.0 0.1 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 AKAP_110 PF05716.8 KZN93217.1 - 0.15 10.0 0.0 0.22 9.4 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) HlyIII PF03006.15 KZN93218.1 - 2.2e-61 207.0 11.4 2.6e-61 206.8 7.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related Zn_clus PF00172.13 KZN93219.1 - 8.2e-08 32.0 8.0 8.2e-08 32.0 5.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KZN93220.1 - 4.7e-33 114.4 4.4 6.4e-33 114.0 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93220.1 - 7.7e-27 94.5 0.8 3.9e-26 92.2 0.5 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93220.1 - 3.2e-18 66.0 1.2 4.2e-18 65.6 0.8 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KZN93220.1 - 0.001 18.7 1.3 0.0018 17.9 0.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KZN93220.1 - 0.0081 15.0 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.16 KZN93220.1 - 0.014 15.2 0.6 0.024 14.5 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 KZN93220.1 - 0.019 14.4 0.4 0.028 13.8 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KZN93220.1 - 0.046 13.7 0.4 0.082 12.9 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KZN93220.1 - 0.056 12.8 0.3 0.09 12.1 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.6 KZN93220.1 - 0.07 12.2 0.2 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Methyltransf_26 PF13659.1 KZN93220.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KZN93220.1 - 0.076 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 KZN93221.1 - 8.5e-60 202.0 0.0 1.1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93221.1 - 4.2e-34 117.8 0.0 5.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN93221.1 - 3e-06 26.3 0.0 0.00041 19.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KZN93221.1 - 0.0011 18.6 0.0 0.0049 16.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN93221.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KZN93221.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KZN93222.1 - 7.3e-50 169.5 0.0 1.2e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93222.1 - 3.9e-22 78.5 0.0 9.8e-22 77.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KZN93222.1 - 0.061 12.1 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 KZN93223.1 - 4.3e-21 75.1 20.5 4.8e-21 74.9 14.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF1851 PF08906.6 KZN93223.1 - 0.22 11.5 1.0 1.5 8.8 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1851) Cyt-b5 PF00173.23 KZN93225.1 - 1.6e-13 50.2 0.0 2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FixQ PF05545.6 KZN93225.1 - 0.1 12.2 0.3 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ish1 PF10281.4 KZN93226.1 - 9.6e-81 265.3 20.9 5.3e-13 48.7 0.0 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KZN93226.1 - 1.5e-10 40.4 0.1 0.033 13.7 0.1 5.4 6 0 0 6 6 6 2 HeH/LEM domain SAP PF02037.22 KZN93226.1 - 2e-10 39.8 0.0 1.1 8.9 0.0 6.3 6 1 0 6 6 6 4 SAP domain APC2 PF08672.6 KZN93226.1 - 7.7e-06 26.0 4.5 3.6 7.9 0.0 6.5 7 0 0 7 7 7 1 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 KZN93226.1 - 0.00014 21.5 5.2 9.2 6.0 0.0 5.6 6 0 0 6 6 6 1 Slx4 endonuclease LEM PF03020.10 KZN93226.1 - 0.00014 21.2 0.0 13 5.3 0.0 5.3 6 0 0 6 6 6 1 LEM domain Thymopoietin PF08198.6 KZN93226.1 - 0.019 14.4 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Thymopoietin protein Amidase02_C PF12123.3 KZN93226.1 - 0.027 14.0 0.0 2.2 7.9 0.1 3.7 4 0 0 4 4 4 0 N-acetylmuramoyl-l-alanine amidase SAM_2 PF07647.12 KZN93226.1 - 0.17 11.7 5.9 15 5.4 0.1 4.7 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) Phasin PF05597.6 KZN93226.1 - 2 8.2 8.3 2.3 7.9 0.1 4.1 5 0 0 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1470 PF07336.6 KZN93226.1 - 2.3 8.5 16.1 6.5 7.0 0.2 5.7 3 1 3 7 7 7 0 Protein of unknown function (DUF1470) APH PF01636.18 KZN93227.1 - 4.2e-15 56.1 0.0 1.2e-14 54.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KZN93227.1 - 0.029 12.9 0.0 0.23 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) DUF481 PF04338.7 KZN93227.1 - 0.11 12.1 0.1 11 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF481 PQ-loop PF04193.9 KZN93228.1 - 8.8e-21 73.2 23.3 6.1e-12 44.9 2.1 3.6 3 1 1 4 4 4 2 PQ loop repeat NTF2 PF02136.15 KZN93229.1 - 1.7e-34 118.7 0.3 1.9e-34 118.5 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 KZN93230.1 - 1.7e-17 62.7 0.0 3.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 KZN93230.1 - 0.16 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3169 PF11368.3 KZN93231.1 - 0.074 12.2 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1049 PF06305.6 KZN93231.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Not1 PF04054.10 KZN93232.1 - 1.8e-137 458.2 0.3 3.5e-137 457.2 0.2 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KZN93232.1 - 2.4e-51 173.2 1.0 4.9e-51 172.2 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF3696 PF12476.3 KZN93232.1 - 0.038 13.9 0.2 0.33 10.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3696) Seipin PF06775.9 KZN93233.1 - 1.1e-64 217.6 0.0 1.5e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 KZN93234.1 - 7.5e-57 192.4 0.0 1.1e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KZN93234.1 - 4.9e-06 25.5 0.0 0.00042 19.2 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KZN93234.1 - 1.1e-05 25.2 0.1 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain SurE PF01975.12 KZN93234.1 - 3.9e-05 23.0 0.0 6.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Dala_Dala_lig_C PF07478.8 KZN93234.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KZN93234.1 - 0.19 11.6 0.0 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain PrpF PF04303.8 KZN93235.1 - 2.5e-106 355.5 0.2 2.9e-106 355.3 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Pex14_N PF04695.8 KZN93237.1 - 4.7e-45 152.9 0.0 4.7e-45 152.9 0.0 3.6 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 KZN93237.1 - 0.0052 16.6 1.6 0.044 13.6 1.2 2.2 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.4 KZN93237.1 - 0.0081 16.2 1.6 0.0081 16.2 1.1 2.3 2 1 0 2 2 2 1 Zinc finger-containing protein BID PF06393.6 KZN93237.1 - 0.025 13.9 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF3584 PF12128.3 KZN93237.1 - 0.03 11.6 3.8 0.041 11.2 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KZN93237.1 - 0.049 13.2 1.3 0.11 12.1 0.9 1.6 1 1 0 1 1 1 0 IncA protein Cytochrom_B562 PF07361.6 KZN93237.1 - 0.073 13.4 0.7 0.18 12.2 0.5 1.7 1 0 0 1 1 1 0 Cytochrome b562 GRIM-19 PF06212.7 KZN93237.1 - 0.12 12.0 0.5 0.27 10.9 0.4 1.5 1 0 0 1 1 1 0 GRIM-19 protein TRADD_N PF09034.5 KZN93237.1 - 0.14 12.1 0.6 0.24 11.4 0.4 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain ERM PF00769.14 KZN93237.1 - 0.15 11.5 4.4 0.18 11.3 2.1 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ndc80_HEC PF03801.8 KZN93238.1 - 2.3e-61 205.9 0.0 5e-61 204.8 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family CENP-F_leu_zip PF10473.4 KZN93238.1 - 0.0028 17.4 10.1 0.0028 17.4 7.0 4.3 2 2 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KZN93238.1 - 0.0038 16.7 46.4 0.0047 16.4 15.4 2.6 2 1 0 2 2 2 2 Intermediate filament protein Adenylsucc_synt PF00709.16 KZN93238.1 - 0.7 8.4 11.9 4.3 5.8 0.2 2.3 2 0 0 2 2 2 0 Adenylosuccinate synthetase Reo_sigmaC PF04582.7 KZN93238.1 - 2.8 7.0 6.6 0.31 10.1 0.3 2.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein RNase_H PF00075.19 KZN93239.1 - 4.5e-06 27.0 0.1 6.7e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KZN93239.1 - 0.041 13.6 0.1 0.081 12.7 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like PT PF04886.7 KZN93240.1 - 0.02 14.1 55.0 0.1 11.9 8.0 4.2 3 2 1 4 4 4 0 PT repeat Fungal_trans PF04082.13 KZN93242.1 - 3.7e-22 78.4 0.0 5.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93242.1 - 5.6e-08 32.5 10.5 1.1e-07 31.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF PF05092.7 KZN93242.1 - 0.12 10.7 2.1 0.18 10.1 1.5 1.1 1 0 0 1 1 1 0 Per os infectivity GST_C PF00043.20 KZN93244.1 - 1.3e-14 53.9 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KZN93244.1 - 1.5e-13 50.6 0.0 5.5e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KZN93244.1 - 7.9e-13 48.4 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN93244.1 - 3.8e-10 39.6 0.0 8.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN93244.1 - 1.3e-09 38.3 0.1 1.9e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN93244.1 - 3.1e-06 26.9 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.17 KZN93245.1 - 2.5e-15 56.2 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 KZN93246.1 - 1.5e-28 99.5 32.5 1.5e-28 99.5 22.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 KZN93247.1 - 4.6e-24 84.9 0.0 6.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93247.1 - 8e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93247.1 - 0.00019 22.0 0.0 0.00046 20.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93247.1 - 0.00053 20.4 0.0 0.0028 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93247.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN93247.1 - 0.0041 17.1 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93247.1 - 0.0069 15.9 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 KZN93247.1 - 2.6 7.3 9.2 3.3 7.0 6.4 1.1 1 0 0 1 1 1 0 Vta1 like DAO PF01266.19 KZN93248.1 - 2.6e-50 171.3 0.2 3.1e-50 171.1 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KZN93248.1 - 1.2e-07 31.6 0.8 0.018 14.7 0.1 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KZN93248.1 - 1.2e-06 28.5 0.0 0.0001 22.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN93248.1 - 7.4e-06 25.1 0.1 0.00059 18.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KZN93248.1 - 2e-05 23.4 0.0 0.015 13.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 KZN93248.1 - 5.5e-05 23.3 0.1 0.0058 16.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN93248.1 - 9.6e-05 21.4 0.0 0.00072 18.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KZN93248.1 - 0.00017 21.9 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN93248.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KZN93248.1 - 0.0018 17.4 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN93248.1 - 0.002 17.0 0.0 0.32 9.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.13 KZN93248.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 KZN93248.1 - 0.036 13.1 0.0 0.27 10.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KZN93248.1 - 0.071 12.2 0.0 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TBP PF00352.16 KZN93249.1 - 4.6e-70 231.0 0.1 4.4e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KZN93249.1 - 0.00012 22.1 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KZN93249.1 - 0.037 14.3 0.4 0.055 13.7 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) ETF_QO PF05187.8 KZN93250.1 - 5.6e-44 148.6 0.0 9.2e-44 147.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KZN93250.1 - 1e-07 31.2 1.6 0.00073 18.5 0.4 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN93250.1 - 1.3e-07 30.8 0.4 0.00093 18.1 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN93250.1 - 2.9e-06 27.1 0.0 8.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KZN93250.1 - 9.7e-06 24.9 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN93250.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN93250.1 - 0.00034 19.1 0.5 0.00054 18.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KZN93250.1 - 0.00063 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KZN93250.1 - 0.001 18.2 0.1 0.0026 16.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KZN93250.1 - 0.0014 18.9 0.1 3.5 8.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN93250.1 - 0.0022 17.7 0.2 0.0062 16.3 0.2 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KZN93250.1 - 0.0023 16.6 0.1 0.15 10.6 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 KZN93250.1 - 0.0027 16.8 0.0 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Fer4_7 PF12838.2 KZN93250.1 - 0.0033 17.7 1.0 0.01 16.1 0.7 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KZN93250.1 - 0.037 12.9 0.3 0.057 12.3 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KZN93250.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KZN93250.1 - 0.097 11.5 0.2 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3319 PF11782.3 KZN93252.1 - 0.041 13.6 0.2 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) DUF1814 PF08843.6 KZN93253.1 - 2.4e-08 34.0 0.3 7.1e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 KZN93253.1 - 0.067 12.6 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) NTP_transf_2 PF01909.18 KZN93253.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase domain Cyclin_N PF00134.18 KZN93254.1 - 7e-16 57.9 1.2 1.7e-15 56.6 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KZN93254.1 - 3.4e-06 26.9 0.1 0.00027 20.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 KZN93254.1 - 1.8 8.4 4.9 1.4 8.7 0.5 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat EAF PF09816.4 KZN93255.1 - 1.3e-23 83.0 0.0 2.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor cNMP_binding PF00027.24 KZN93257.1 - 2.6e-42 142.5 0.0 3.7e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_4 PF13661.1 KZN93258.1 - 2.3e-09 36.7 0.0 5.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KZN93258.1 - 2.8e-09 37.4 0.0 4.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KZN93258.1 - 0.00073 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 KZN93259.1 - 5.7e-16 58.3 0.0 1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KZN93259.1 - 3e-06 27.2 0.0 5.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Aminotran_1_2 PF00155.16 KZN93260.1 - 7.2e-65 219.2 0.0 8.9e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KZN93260.1 - 0.0043 16.2 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.23 KZN93261.1 - 6.8e-44 149.8 0.0 9.4e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN93261.1 - 7.3e-05 23.6 0.0 0.00021 22.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3368 PF11848.3 KZN93261.1 - 0.14 11.7 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Peptidase_M16_C PF05193.16 KZN93262.1 - 8.3e-49 165.7 0.0 3.4e-48 163.7 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KZN93262.1 - 1.8e-40 138.0 0.0 5.4e-39 133.3 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tom22 PF04281.8 KZN93263.1 - 2.5e-53 179.2 0.7 2.8e-53 179.1 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 KZN93264.1 - 1.8e-43 147.5 0.0 1.8e-43 147.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Tir_receptor_C PF07489.6 KZN93264.1 - 0.048 13.3 1.7 0.085 12.5 1.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Sugar_tr PF00083.19 KZN93265.1 - 5.9e-95 318.4 22.2 6.8e-95 318.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93265.1 - 1.6e-28 99.4 28.8 5.3e-20 71.4 4.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PGBA_C PF15437.1 KZN93265.1 - 0.81 9.8 7.8 1.4 9.1 5.4 1.3 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Peptidase_S28 PF05577.7 KZN93266.1 - 0.0011 17.6 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 TPD52 PF04201.10 KZN93266.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Lipase_3 PF01764.20 KZN93268.1 - 1e-25 89.9 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF1031 PF06275.6 KZN93268.1 - 0.098 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) TauD PF02668.11 KZN93269.1 - 1.2e-33 116.9 0.1 1.9e-33 116.2 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KZN93269.1 - 0.084 11.7 0.0 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 CsiD MFS_1 PF07690.11 KZN93270.1 - 2.3e-33 115.3 25.2 2.3e-33 115.3 17.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 KZN93270.1 - 0.017 15.0 0.7 0.017 15.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SPC12 PF06645.8 KZN93270.1 - 7.9 6.3 11.5 1.3 8.9 1.4 3.7 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FMO-like PF00743.14 KZN93271.1 - 2.2e-15 55.8 0.0 3.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KZN93271.1 - 3.4e-14 53.4 0.0 8.5e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KZN93271.1 - 4.2e-07 29.8 0.0 1.2e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KZN93271.1 - 2e-06 26.9 0.0 0.00043 19.2 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KZN93271.1 - 3e-06 27.2 0.0 0.00013 21.8 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN93271.1 - 1.2e-05 25.2 0.0 8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KZN93271.1 - 0.0015 18.8 0.0 0.58 10.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93271.1 - 0.0049 15.9 0.0 0.032 13.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KZN93271.1 - 0.048 12.7 0.3 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KZN93271.1 - 0.075 11.4 0.3 0.31 9.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KZN93271.1 - 0.29 9.9 0.4 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-RING_5 PF14634.1 KZN93272.1 - 2.2e-05 24.0 6.7 8e-05 22.2 4.8 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KZN93272.1 - 3.3e-05 23.4 5.8 9.9e-05 21.9 4.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KZN93272.1 - 0.0071 16.1 8.2 0.037 13.8 6.1 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KZN93272.1 - 0.0081 16.1 9.4 0.046 13.7 6.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN93272.1 - 0.013 15.2 7.3 0.033 13.8 5.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KZN93272.1 - 0.018 14.9 0.7 0.032 14.1 0.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 KZN93272.1 - 0.045 13.6 6.5 0.051 13.4 2.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KZN93272.1 - 0.071 12.8 2.1 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger C1_3 PF07649.7 KZN93272.1 - 0.42 10.6 8.4 2.5 8.2 2.6 2.4 2 0 0 2 2 2 0 C1-like domain zf-RING_6 PF14835.1 KZN93272.1 - 5 6.9 7.1 18 5.1 4.9 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF3405 PF11885.3 KZN93273.1 - 3.2e-224 744.7 0.7 3.9e-224 744.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Fic PF02661.13 KZN93274.1 - 3.8e-18 65.9 0.0 1.8e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family Arf PF00025.16 KZN93275.1 - 6.2e-79 263.2 0.1 7.1e-79 263.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KZN93275.1 - 5.2e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KZN93275.1 - 3.3e-13 49.3 0.0 3.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KZN93275.1 - 3.9e-12 45.5 1.5 2.2e-09 36.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KZN93275.1 - 5.8e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KZN93275.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN93275.1 - 2.9e-06 27.2 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KZN93275.1 - 0.011 14.7 0.3 0.02 14.0 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KZN93275.1 - 0.011 15.1 0.1 0.078 12.4 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KZN93275.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 KZN93276.1 - 0.0013 17.7 1.2 2.6 6.9 0.2 3.3 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein VIT1 PF01988.14 KZN93276.1 - 0.027 13.9 0.8 0.11 11.9 0.3 1.9 2 0 0 2 2 2 0 VIT family SieB PF14163.1 KZN93276.1 - 0.03 13.9 0.4 0.056 13.0 0.3 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B Ribosomal_L1 PF00687.16 KZN93278.1 - 6.2e-51 172.8 1.1 7.5e-51 172.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family UCH PF00443.24 KZN93279.1 - 0.16 11.0 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WH2 PF02205.15 KZN93280.1 - 4.7e-11 41.9 0.7 1.3e-10 40.5 0.5 1.8 1 0 0 1 1 1 1 WH2 motif LSM PF01423.17 KZN93281.1 - 7.3e-15 54.2 0.2 9.2e-15 53.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.10 KZN93283.1 - 3.3e-94 315.2 7.8 3.7e-94 315.0 5.4 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 KZN93283.1 - 0.034 14.5 14.8 0.04 14.3 0.8 2.9 3 1 0 3 3 3 0 DoxX DUF3021 PF11457.3 KZN93283.1 - 0.71 9.7 9.4 1.3 8.9 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) IU_nuc_hydro PF01156.14 KZN93285.1 - 1.6e-53 181.9 0.0 1.3e-52 179.0 0.0 1.9 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2249 PF10006.4 KZN93285.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) HLH PF00010.21 KZN93286.1 - 9.5e-15 54.0 0.1 3.2e-14 52.3 0.1 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fungal_trans PF04082.13 KZN93287.1 - 7.1e-17 61.1 0.1 1.1e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93287.1 - 6.2e-09 35.6 11.0 1.5e-08 34.3 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2973 PF11189.3 KZN93287.1 - 0.082 12.6 0.6 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) CHORD PF04968.7 KZN93288.1 - 0.075 13.2 0.8 0.075 13.2 0.6 2.2 2 0 0 2 2 2 0 CHORD MFS_1 PF07690.11 KZN93290.1 - 2.2e-38 131.8 30.2 2.2e-38 131.8 20.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93290.1 - 3.3e-14 52.3 2.6 3.3e-14 52.3 1.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3100 PF11299.3 KZN93290.1 - 0.011 14.9 2.0 0.23 10.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) Mito_fiss_reg PF05308.6 KZN93290.1 - 0.16 11.3 0.3 0.21 10.9 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Zn_clus PF00172.13 KZN93291.1 - 4.8e-06 26.3 10.0 8.1e-06 25.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN93291.1 - 0.0045 15.8 0.4 0.0082 15.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab_C PF00306.22 KZN93291.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Pyr_redox_3 PF13738.1 KZN93292.1 - 1.2e-26 94.0 0.2 4.5e-26 92.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN93292.1 - 1.2e-23 83.1 0.0 3.4e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KZN93292.1 - 1.1e-13 51.5 0.0 4.5e-10 39.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN93292.1 - 8.6e-12 44.6 0.6 1.9e-09 36.9 0.1 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KZN93292.1 - 1.1e-08 34.5 0.8 0.00044 19.4 0.3 3.2 2 1 1 3 3 3 2 FAD binding domain 2-Hacid_dh_C PF02826.14 KZN93292.1 - 5.4e-07 28.9 0.3 0.0062 15.7 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KZN93292.1 - 6.9e-07 29.5 0.1 0.011 16.1 0.1 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN93292.1 - 1.9e-06 27.7 0.0 0.00016 21.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KZN93292.1 - 5.5e-05 22.9 0.1 1.2 8.8 0.0 3.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding IlvN PF07991.7 KZN93292.1 - 0.00015 21.1 0.3 0.0011 18.3 0.2 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KZN93292.1 - 0.00024 20.8 0.6 0.027 14.1 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KZN93292.1 - 0.00098 18.9 0.7 0.87 9.4 0.4 2.4 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.19 KZN93292.1 - 0.0011 17.9 0.2 0.011 14.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KZN93292.1 - 0.0016 18.6 0.0 0.11 12.8 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 KZN93292.1 - 0.0019 18.1 0.1 0.87 9.6 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 KZN93292.1 - 0.0037 16.2 0.0 0.32 9.8 0.0 2.9 4 0 0 4 4 4 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN93292.1 - 0.0068 14.9 0.1 0.38 9.1 0.0 2.5 3 0 0 3 3 3 1 HI0933-like protein ELFV_dehydrog PF00208.16 KZN93292.1 - 0.017 14.6 0.8 0.034 13.7 0.3 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 KZN93292.1 - 0.02 14.9 0.0 2.2 8.4 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KZN93292.1 - 0.03 13.1 0.1 7.2 5.3 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A F420_oxidored PF03807.12 KZN93292.1 - 0.036 14.4 0.0 6.1 7.3 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KZN93292.1 - 0.04 13.3 0.0 16 4.9 0.0 2.8 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 KZN93292.1 - 0.04 13.4 0.0 3 7.3 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KZN93292.1 - 0.056 12.3 0.4 5.1 5.8 0.0 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 KZN93292.1 - 0.081 12.0 0.1 14 4.6 0.0 2.8 4 0 0 4 4 3 0 Thi4 family IcmL PF11393.3 KZN93292.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein NAD_Gly3P_dh_N PF01210.18 KZN93292.1 - 0.092 12.4 0.0 0.95 9.1 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4147 PF13660.1 KZN93292.1 - 0.16 11.0 0.0 8.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) DUF4408 PF14364.1 KZN93294.1 - 0.016 14.7 0.5 0.016 14.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) GFO_IDH_MocA PF01408.17 KZN93295.1 - 6.2e-17 62.2 0.0 1e-16 61.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.2 KZN93297.1 - 5.2e-11 42.8 0.3 6.9e-11 42.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93297.1 - 0.00026 20.7 0.0 0.00045 19.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KZN93298.1 - 5.7e-20 71.8 0.0 7.7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN93298.1 - 8.5e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KZN93298.1 - 2.6e-07 29.7 0.0 3.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 KZN93298.1 - 4.7e-07 29.2 0.0 0.00093 18.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KZN93298.1 - 2.3e-05 23.3 0.0 4.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 KZN93298.1 - 4.7e-05 23.3 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KZN93298.1 - 0.00035 20.0 0.0 0.00075 18.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.23 KZN93298.1 - 0.0022 16.7 0.0 0.008 14.9 0.0 1.9 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.15 KZN93298.1 - 0.093 12.2 0.0 2.1 7.8 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 KZN93298.1 - 0.12 10.8 0.0 1.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FAD_binding_4 PF01565.18 KZN93299.1 - 9.6e-23 80.1 2.0 1.8e-22 79.2 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KZN93299.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 KZN93299.1 - 0.014 14.7 0.0 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain NAD_binding_10 PF13460.1 KZN93300.1 - 1.9e-11 44.3 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 KZN93300.1 - 0.0004 20.6 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KZN93300.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KZN93300.1 - 0.04 14.3 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KZN93300.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.10 KZN93300.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 KZN93300.1 - 0.13 11.6 0.4 0.36 10.2 0.3 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 KZN93301.1 - 1.8e-08 34.1 6.9 4.1e-08 33.0 4.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.8 KZN93302.1 - 7.8e-14 52.0 10.1 7.8e-14 52.0 7.0 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 4HBT PF03061.17 KZN93303.1 - 8.2e-13 48.2 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily CLASP_N PF12348.3 KZN93304.1 - 3e-148 491.2 0.1 5.4e-86 287.6 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 KZN93304.1 - 7.5e-10 38.0 0.1 0.018 15.1 0.0 6.0 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 KZN93304.1 - 3.5e-07 30.2 0.0 0.00075 19.3 0.0 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KZN93304.1 - 4.8e-06 26.7 0.4 0.062 13.5 0.3 4.7 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 KZN93304.1 - 0.00028 21.2 0.6 1.6 9.3 0.0 4.3 6 0 0 6 6 6 2 HEAT-like repeat Condensin2nSMC PF12422.3 KZN93304.1 - 0.037 13.7 0.0 7.9 6.2 0.0 3.3 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Adaptin_N PF01602.15 KZN93304.1 - 0.21 9.8 1.2 0.76 8.0 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region MIF4G_like_2 PF09090.6 KZN93304.1 - 0.24 10.5 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 MIF4G like BSP PF04450.7 KZN93305.1 - 8.1e-74 247.5 0.0 9.6e-74 247.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KZN93305.1 - 0.00029 20.8 0.0 0.00056 19.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KZN93305.1 - 0.027 14.1 0.2 0.058 13.0 0.1 1.6 2 0 0 2 2 2 0 SprT-like family Ribonuclease_3 PF00636.21 KZN93306.1 - 3.6e-07 30.6 0.0 9.8e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KZN93306.1 - 2.8e-06 27.2 0.0 0.00048 20.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KZN93306.1 - 8.8e-06 26.2 1.4 6e-05 23.5 0.0 2.8 4 0 0 4 4 4 1 Double-stranded RNA binding motif PfkB PF00294.19 KZN93308.1 - 9.1e-12 44.7 0.0 2.5e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.14 KZN93309.1 - 4.4e-79 266.0 17.0 3.5e-76 256.4 11.8 2.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KZN93309.1 - 8.4e-57 190.9 0.1 1.1e-56 190.5 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KZN93309.1 - 0.14 11.5 4.5 0.56 9.6 2.4 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor C LdpA_C PF12617.3 KZN93309.1 - 0.16 11.2 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal DUF4210 PF13915.1 KZN93310.1 - 6.2e-27 93.6 0.6 1.7e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KZN93310.1 - 3.6e-21 74.7 1.8 3.9e-21 74.6 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis DUF605 PF04652.11 KZN93311.1 - 0.9 8.8 10.0 1.2 8.4 6.9 1.1 1 0 0 1 1 1 0 Vta1 like rRNA_processing PF08524.6 KZN93311.1 - 1.6 8.5 29.0 0.07 12.9 8.4 2.2 1 1 1 2 2 2 0 rRNA processing RR_TM4-6 PF06459.7 KZN93311.1 - 4.5 7.1 13.0 5.9 6.7 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec5 PF15469.1 KZN93312.1 - 1.2e-35 122.8 0.0 1.2e-34 119.6 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KZN93312.1 - 1.7e-05 24.5 0.0 6e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 DUF4468 PF14730.1 KZN93312.1 - 0.0063 16.1 0.2 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4468) with TBP-like fold Iso_dh PF00180.15 KZN93313.1 - 1.2e-99 333.5 0.0 1.5e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KZN93313.1 - 0.021 14.6 0.1 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Eaf7 PF07904.8 KZN93314.1 - 4.5e-30 103.4 0.0 8.8e-30 102.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 KZN93315.1 - 7.2e-73 245.7 0.0 9.3e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Mo-co_dimer PF03404.11 KZN93316.1 - 3.7e-55 185.1 0.4 1.3e-54 183.3 0.1 2.0 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KZN93316.1 - 1.5e-46 157.8 0.0 2.9e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KZN93316.1 - 3e-31 107.4 0.0 5.6e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KZN93316.1 - 6.9e-27 94.1 0.0 1.4e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KZN93316.1 - 2.3e-19 68.9 0.0 4.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KZN93316.1 - 0.0022 17.8 0.0 0.63 9.9 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain LysM PF01476.15 KZN93317.1 - 3.2e-20 71.7 0.4 1.8e-06 27.7 0.0 5.1 5 0 0 5 5 5 4 LysM domain NLPC_P60 PF00877.14 KZN93317.1 - 0.0047 16.7 1.3 7.1 6.5 0.0 3.9 4 0 0 4 4 4 2 NlpC/P60 family Hce2 PF14856.1 KZN93317.1 - 0.051 13.4 3.7 7.8 6.4 0.0 3.4 3 0 0 3 3 3 0 Pathogen effector; putative necrosis-inducing factor MULE PF10551.4 KZN93318.1 - 1.6e-06 28.1 0.0 3.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain FXR1P_C PF12235.3 KZN93318.1 - 0.013 15.5 11.5 0.015 15.4 7.3 1.5 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal HGD-D PF06050.8 KZN93318.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component API5 PF05918.6 KZN93318.1 - 0.14 10.5 1.3 0.23 9.9 0.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-RING_2 PF13639.1 KZN93320.1 - 0.031 14.1 18.2 0.052 13.3 12.6 1.4 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.2 KZN93320.1 - 1.5 8.9 18.4 2.7 8.0 12.8 1.4 1 0 0 1 1 1 0 RING-variant domain Pkinase_Tyr PF07714.12 KZN93322.1 - 0.001 18.1 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KZN93322.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF3435 PF11917.3 KZN93323.1 - 1.7e-159 531.0 1.1 2.5e-159 530.5 0.2 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KZN93323.1 - 0.28 11.5 2.6 0.63 10.5 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type OmpH PF03938.9 KZN93323.1 - 9.6 6.1 18.0 28 4.6 6.6 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Alginate_lyase PF05426.7 KZN93324.1 - 3.2e-20 72.6 0.8 6.3e-20 71.6 0.6 1.4 1 1 0 1 1 1 1 Alginate lyase Dioxygenase_C PF00775.16 KZN93325.1 - 4.1e-50 169.5 0.0 5.5e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KZN93325.1 - 6.7e-17 61.2 0.1 1.4e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Catechol dioxygenase N terminus Fe-ADH PF00465.14 KZN93326.1 - 1.1e-74 251.2 1.1 1.3e-74 251.0 0.8 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KZN93326.1 - 1.1e-15 57.6 0.1 1.6e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase FAD_binding_3 PF01494.14 KZN93327.1 - 1.3e-70 238.2 0.0 8.8e-70 235.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KZN93327.1 - 1.6e-25 89.6 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 KZN93327.1 - 0.00013 20.8 0.0 0.00027 19.8 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KZN93327.1 - 0.039 12.8 0.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HEAT_EZ PF13513.1 KZN93328.1 - 2.2e-12 47.0 10.0 1.1e-07 32.1 0.0 7.1 6 2 2 8 8 8 2 HEAT-like repeat HEAT PF02985.17 KZN93328.1 - 2.8e-11 42.4 13.3 0.0071 16.3 0.0 9.0 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 KZN93328.1 - 1.4e-10 41.2 8.0 0.00069 19.8 0.0 6.4 4 3 2 6 6 6 3 HEAT repeats IBN_N PF03810.14 KZN93328.1 - 2e-07 30.8 0.9 2e-07 30.8 0.6 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KZN93328.1 - 4.4e-06 26.2 0.1 0.023 14.0 0.0 4.0 2 2 0 3 3 3 2 CLASP N terminal Dopey_N PF04118.9 KZN93328.1 - 0.093 11.4 0.9 7.9 5.1 0.1 2.8 2 1 0 3 3 3 0 Dopey, N-terminal HEAT_PBS PF03130.11 KZN93328.1 - 0.1 13.1 1.3 60 4.5 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KZN93328.1 - 0.27 11.1 3.3 6.2 6.8 0.2 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.14 KZN93329.1 - 7e-24 84.1 0.0 9.5e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 KZN93330.1 - 6.6e-20 71.7 0.0 8.7e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.18 KZN93331.1 - 1.4e-08 33.9 0.0 6.1e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 KZN93331.1 - 0.0015 18.6 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 KZN93332.1 - 1.7e-82 275.6 0.0 3.8e-82 274.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Mem_trans PF03547.13 KZN93333.1 - 3.1e-55 187.0 0.0 6.3e-55 186.0 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein Glyco_transf_90 PF05686.7 KZN93334.1 - 8.8e-20 70.7 6.1 1.1e-17 63.8 1.1 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 90 Taeniidae_ag PF05596.6 KZN93334.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Taeniidae antigen Cu-oxidase_3 PF07732.10 KZN93335.1 - 3.5e-37 126.7 0.3 3.8e-34 116.9 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN93335.1 - 1.9e-30 105.1 1.4 1.9e-30 105.1 1.0 2.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KZN93335.1 - 1.7e-17 63.7 0.3 9.5e-17 61.3 0.0 2.3 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 KZN93336.1 - 1e-71 242.1 6.0 1e-71 242.1 4.2 1.4 2 0 0 2 2 2 1 Phosphoesterase family GPI-anchored PF10342.4 KZN93337.1 - 0.0027 18.1 0.1 0.0044 17.4 0.1 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.17 KZN93338.1 - 1.8e-51 175.0 0.0 2.4e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.15 KZN93339.1 - 5.4e-61 205.8 0.1 1.6e-60 204.2 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KZN93339.1 - 2.4e-14 52.5 0.0 5.4e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KZN93339.1 - 4.6e-09 36.3 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.16 KZN93340.1 - 6.4e-74 247.7 0.0 7.9e-74 247.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Zn_clus PF00172.13 KZN93341.1 - 1.8e-07 30.9 16.1 3e-07 30.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.5 KZN93342.1 - 2.3e-27 95.2 0.2 2.5e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 CVNH domain HEAT_EZ PF13513.1 KZN93343.1 - 2.5e-31 107.3 1.7 9.1e-13 48.2 0.0 10.0 8 1 3 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 KZN93343.1 - 3e-21 75.5 4.7 1.1e-07 31.9 0.0 8.8 4 3 7 11 11 11 6 HEAT repeats HEAT PF02985.17 KZN93343.1 - 1.8e-17 61.7 23.4 0.00043 20.1 0.0 11.0 13 0 0 13 13 13 5 HEAT repeat Vac14_Fab1_bd PF12755.2 KZN93343.1 - 2.2e-10 40.8 0.0 0.12 12.8 0.0 6.3 4 3 2 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KZN93343.1 - 8e-09 34.3 0.1 0.0053 15.1 0.0 3.3 3 1 1 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.2 KZN93343.1 - 2.9e-07 30.4 2.8 0.011 15.5 0.2 5.6 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KZN93343.1 - 7.9e-06 25.7 0.6 0.019 14.8 0.0 4.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.7 KZN93343.1 - 5e-05 23.0 2.8 0.018 14.7 0.0 4.0 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KZN93343.1 - 7e-05 22.2 1.0 4.2 6.6 0.0 5.6 4 3 2 6 6 6 1 CLASP N terminal MMS19_C PF12460.3 KZN93343.1 - 0.00016 20.5 7.3 4.5 5.8 0.0 6.2 6 2 0 6 6 6 2 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 KZN93343.1 - 0.0011 19.2 1.2 15 6.3 0.0 5.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Arm PF00514.18 KZN93343.1 - 0.002 17.8 4.6 0.98 9.3 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 KZN93343.1 - 0.031 12.5 0.0 1.4 7.1 0.0 2.8 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Syja_N PF02383.13 KZN93344.1 - 6.8e-97 324.0 0.0 9.6e-97 323.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KZN93344.1 - 2.6e-37 126.7 0.0 4.5e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.9 KZN93345.1 - 1.2e-107 359.3 15.8 1.5e-107 358.9 11.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KZN93345.1 - 8.8e-05 22.6 6.0 8.8e-05 22.6 4.1 3.3 2 1 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 KZN93345.1 - 0.00095 19.2 10.1 0.00095 19.2 7.0 3.2 3 1 1 4 4 4 2 EamA-like transporter family DUF2937 PF11157.3 KZN93345.1 - 0.24 10.6 1.0 0.86 8.9 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF2420 PF10336.4 KZN93346.1 - 3.7e-12 45.8 1.2 4.3e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 KZN93347.1 - 6.1e-16 58.3 0.0 9.6e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KZN93347.1 - 1.3e-07 31.4 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 KZN93347.1 - 0.0075 15.4 0.0 0.056 12.6 0.0 2.0 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.6 KZN93347.1 - 0.021 14.9 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF3647 PF12363.3 KZN93347.1 - 0.053 13.6 0.8 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 Phage protein Fungal_trans PF04082.13 KZN93348.1 - 2.9e-26 91.9 0.5 9.4e-26 90.2 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93348.1 - 2.5e-05 24.0 16.2 7.5e-05 22.5 11.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OMPdecase PF00215.19 KZN93350.1 - 3.1e-05 23.4 0.0 8.8e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Cyt-b5 PF00173.23 KZN93351.1 - 7.4e-21 73.7 0.7 5.5e-20 70.9 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KZN93351.1 - 2.2e-08 34.4 24.1 1.1e-07 32.2 15.9 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily ATP_synt_I PF03899.10 KZN93351.1 - 0.0079 16.3 4.2 0.21 11.7 0.1 2.2 2 0 0 2 2 2 2 ATP synthase I chain Anth_synt_I_N PF04715.8 KZN93351.1 - 0.035 14.0 0.3 0.076 13.0 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 KZN93351.1 - 0.95 9.1 4.1 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.17 KZN93352.1 - 1.4e-44 149.6 1.7 2.2e-22 78.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN93352.1 - 2.1e-35 120.4 0.1 3.4e-19 68.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KZN93352.1 - 3.9e-30 103.9 0.1 9e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KZN93352.1 - 3.2e-21 74.9 0.1 1.3e-09 37.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KZN93352.1 - 0.0022 17.8 0.1 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 KZN93352.1 - 0.014 15.1 0.2 0.48 10.2 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 RNA_bind PF08675.6 KZN93352.1 - 0.12 12.3 0.0 2 8.4 0.0 2.7 3 0 0 3 3 3 0 RNA binding domain MIP-T3 PF10243.4 KZN93352.1 - 4.3 5.6 15.6 6.3 5.1 10.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PP2C PF00481.16 KZN93353.1 - 1.5e-32 113.0 0.0 1.1e-26 93.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KZN93353.1 - 0.0036 16.7 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 KZN93354.1 - 7.1e-18 64.7 7.3 1e-17 64.2 4.6 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.19 KZN93355.1 - 7.6e-116 387.3 29.6 8.7e-116 387.1 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93355.1 - 1.5e-21 76.4 48.9 1e-17 63.9 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec63 PF02889.11 KZN93358.1 - 8.3e-48 163.2 0.0 1.5e-46 159.1 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KZN93358.1 - 1.7e-17 62.9 0.5 3.6e-17 61.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KZN93358.1 - 0.0083 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) E1-E2_ATPase PF00122.15 KZN93359.1 - 2.4e-63 213.2 1.1 4.2e-63 212.4 0.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KZN93359.1 - 5e-35 120.6 7.8 5e-35 120.6 5.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KZN93359.1 - 2.4e-28 100.0 0.0 2.2e-27 96.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN93359.1 - 1.3e-18 66.1 0.2 3.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KZN93359.1 - 1.1e-14 54.0 0.0 2.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KZN93359.1 - 7.2e-13 49.1 0.0 1.6e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN93359.1 - 2e-05 24.3 0.4 0.0011 18.6 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KZN93360.1 - 1.1e-32 113.0 57.8 1.1e-31 109.8 35.7 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN93360.1 - 4.1e-20 71.5 18.3 6.1e-20 70.9 12.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN93360.1 - 4.5e-14 51.8 2.6 4.5e-14 51.8 1.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Zn_clus PF00172.13 KZN93361.1 - 2.5e-08 33.7 13.9 4.8e-08 32.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MatE PF01554.13 KZN93363.1 - 1.5e-44 151.5 17.8 3.7e-28 98.1 2.4 2.4 2 0 0 2 2 2 2 MatE DUF2269 PF10027.4 KZN93363.1 - 0.014 15.1 2.6 0.014 15.1 1.8 3.4 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) MFS_1 PF07690.11 KZN93364.1 - 1.4e-36 125.9 40.0 4e-33 114.5 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93364.1 - 3.8e-14 52.1 21.8 1.4e-13 50.2 4.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter HSP20 PF00011.16 KZN93365.1 - 0.024 14.4 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Pyr_redox_2 PF07992.9 KZN93366.1 - 4.1e-24 85.5 0.0 3.8e-23 82.4 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN93366.1 - 4.2e-09 36.6 0.3 2.1e-08 34.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN93366.1 - 0.0071 16.4 0.0 1.5 8.8 0.0 3.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NLPC_P60 PF00877.14 KZN93367.1 - 3.6e-18 65.3 0.0 7.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.6 KZN93367.1 - 0.0022 18.1 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Amidase_5 PF05382.8 KZN93367.1 - 0.0058 16.2 0.1 0.015 14.9 0.1 1.8 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.6 KZN93367.1 - 0.022 14.1 0.0 2 7.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Aa_trans PF01490.13 KZN93369.1 - 2.3e-24 85.6 34.1 2.7e-24 85.4 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NADH_Oxid_Nqo15 PF11497.3 KZN93369.1 - 0.041 13.6 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 IBV_3C PF03620.8 KZN93369.1 - 4.2 7.3 6.3 0.66 9.9 0.1 2.9 3 2 0 3 3 3 0 IBV 3C protein Amidase PF01425.16 KZN93370.1 - 1.3e-84 284.6 0.0 1.5e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 KZN93371.1 - 8.4e-28 97.3 1.5 1.1e-27 96.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93371.1 - 3.3e-23 82.6 0.1 4.4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93371.1 - 1.9e-11 43.9 0.4 2.9e-11 43.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN93371.1 - 0.025 14.0 0.1 0.079 12.3 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3391 PF11871.3 KZN93371.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Sod_Fe_N PF00081.17 KZN93372.1 - 1.7e-33 114.7 1.8 1.7e-33 114.7 1.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 KZN93372.1 - 6.3e-30 103.1 0.3 1.6e-29 101.8 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain TPR_11 PF13414.1 KZN93374.1 - 5.1e-11 42.0 4.3 5.9e-05 22.6 0.0 5.2 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 KZN93374.1 - 2.8e-09 36.1 13.0 0.00089 18.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KZN93374.1 - 1e-08 34.4 4.5 0.0037 16.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KZN93374.1 - 6.1e-07 29.6 0.4 0.18 12.1 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KZN93374.1 - 2.1e-06 27.0 0.1 0.011 15.4 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KZN93374.1 - 3.1e-05 24.5 9.4 0.62 10.8 0.5 6.4 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN93374.1 - 3.6e-05 23.5 6.5 0.064 13.1 0.7 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93374.1 - 0.00023 21.5 2.3 3 8.7 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KZN93374.1 - 0.019 15.0 0.0 3.5 7.8 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KZN93374.1 - 0.024 15.0 2.6 83 3.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN93374.1 - 0.05 14.0 2.9 0.69 10.5 0.4 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Polysacc_synt_3 PF13440.1 KZN93377.1 - 0.081 12.3 2.2 0.11 11.9 1.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Acyl_transf_3 PF01757.17 KZN93377.1 - 0.43 9.3 6.9 0.5 9.1 4.8 1.1 1 0 0 1 1 1 0 Acyltransferase family Glyco_hydro_47 PF01532.15 KZN93378.1 - 4.2e-138 460.7 0.0 4.8e-138 460.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 KZN93378.1 - 0.014 15.7 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain GFA PF04828.9 KZN93379.1 - 2.6e-08 33.6 0.1 2.6e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KZN93379.1 - 0.12 11.9 3.7 0.33 10.5 2.6 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Histidinol_dh PF00815.15 KZN93380.1 - 3.8e-175 582.4 4.7 5.2e-175 581.9 3.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KZN93380.1 - 3.8e-24 84.0 0.0 7.5e-24 83.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KZN93380.1 - 2.6e-10 40.4 0.2 7.4e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase SIP PF04954.8 KZN93380.1 - 0.029 14.7 1.2 0.98 9.8 0.2 2.7 2 1 0 2 2 2 0 Siderophore-interacting protein CIAPIN1 PF05093.8 KZN93381.1 - 6.9e-36 122.3 3.1 1.2e-35 121.5 2.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3458 PF11940.3 KZN93381.1 - 0.038 12.8 0.1 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) zf-C2H2_4 PF13894.1 KZN93383.1 - 1.2e-06 28.4 28.1 0.14 12.5 0.0 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN93383.1 - 0.038 14.3 29.3 1.1 9.7 0.3 6.7 7 0 0 7 7 7 0 Zinc finger, C2H2 type OSTMP1 PF09777.4 KZN93383.1 - 0.05 12.7 0.2 0.097 11.8 0.1 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor HAMP PF00672.20 KZN93383.1 - 0.081 13.1 0.2 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 HAMP domain zf-C2H2_2 PF12756.2 KZN93383.1 - 0.3 11.2 3.3 1.3 9.1 0.3 3.1 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KZN93383.1 - 0.3 11.4 16.8 34 4.9 0.5 6.8 6 1 0 6 6 6 0 Zinc-finger double domain zf-Di19 PF05605.7 KZN93383.1 - 0.95 9.6 17.9 0.46 10.6 0.4 4.8 4 1 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KZN93383.1 - 5.2 7.4 7.6 20 5.5 0.2 4.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Utp11 PF03998.8 KZN93384.1 - 1.1e-56 192.3 28.0 1.3e-56 192.1 19.4 1.0 1 0 0 1 1 1 1 Utp11 protein Cmc1 PF08583.5 KZN93385.1 - 6.6e-17 61.0 3.2 6.6e-17 61.0 2.2 1.6 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3287 PF11690.3 KZN93385.1 - 0.038 14.0 3.9 0.065 13.3 2.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF559 PF04480.7 KZN93385.1 - 0.058 13.0 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF559) CHCH PF06747.8 KZN93385.1 - 0.062 13.2 0.1 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 CHCH domain TFIID-31kDa PF02291.10 KZN93386.1 - 5.5e-31 107.0 0.0 2.4e-25 88.7 0.0 2.5 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Med3 PF11593.3 KZN93386.1 - 4.9 6.2 5.9 6 5.9 4.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LNS2 PF08235.8 KZN93387.1 - 2e-71 238.6 0.0 3.1e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KZN93387.1 - 3e-39 133.1 0.0 2.1e-38 130.4 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KZN93387.1 - 0.0033 16.8 0.0 0.062 12.6 0.0 2.6 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 KZN93387.1 - 0.11 12.4 9.4 0.26 11.2 6.5 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nop14 PF04147.7 KZN93387.1 - 2.1 6.1 12.7 2.9 5.6 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KZN93387.1 - 6.9 5.7 13.3 12 4.9 9.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT fn3 PF00041.16 KZN93388.1 - 6.6e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Thg1C PF14413.1 KZN93389.1 - 3.9e-54 181.4 1.7 5.2e-54 181.0 1.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KZN93389.1 - 1.4e-46 157.4 0.0 2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Cylicin_N PF15241.1 KZN93389.1 - 0.015 15.1 0.2 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Cylicin N-terminus DUF4114 PF13448.1 KZN93390.1 - 0.043 14.6 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) WD40 PF00400.27 KZN93391.1 - 4.1e-16 58.1 0.6 0.00019 21.2 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Methyltransf_23 PF13489.1 KZN93392.1 - 6.9e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93392.1 - 2e-08 34.6 0.0 4.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93392.1 - 2.3e-08 34.5 0.0 4.1e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93392.1 - 4.2e-08 33.5 0.0 9.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93392.1 - 8.6e-06 25.4 0.0 2.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KZN93392.1 - 5.9e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KZN93392.1 - 0.0016 18.7 0.0 0.013 15.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN93392.1 - 0.0024 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KZN93392.1 - 0.0034 16.5 0.0 0.051 12.6 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KZN93392.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KZN93392.1 - 0.004 17.1 0.0 0.04 13.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN93392.1 - 0.015 14.3 0.0 0.035 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KZN93392.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.27 KZN93393.1 - 2.4e-15 55.7 4.6 6.4e-08 32.1 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KZN93393.1 - 2.4e-05 24.1 0.1 0.099 12.3 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KZN93393.1 - 0.0019 16.5 0.0 0.0066 14.7 0.0 1.8 3 0 0 3 3 3 1 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.7 KZN93394.1 - 2.6e-118 395.1 0.0 4.4e-118 394.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KZN93394.1 - 6.2e-104 347.1 0.1 1.2e-103 346.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KZN93394.1 - 3.3e-68 228.8 0.0 7.6e-68 227.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KZN93394.1 - 3.2e-62 209.6 0.8 7.3e-62 208.4 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KZN93394.1 - 5.2e-45 152.9 0.0 1.4e-44 151.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KZN93394.1 - 4.9e-43 146.0 9.2 1.8e-42 144.2 5.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KZN93394.1 - 4.9e-38 129.1 0.1 1.3e-37 127.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KZN93394.1 - 2.1e-09 36.6 196.8 0.038 14.1 8.4 14.3 10 3 4 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat YorP PF09629.5 KZN93394.1 - 0.075 13.0 0.0 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 YorP protein Sel1 PF08238.7 KZN93395.1 - 1.9e-37 126.8 46.6 2.5e-05 24.7 0.2 11.8 12 1 0 12 12 12 8 Sel1 repeat TPR_7 PF13176.1 KZN93395.1 - 0.17 11.7 4.4 46 4.1 0.0 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93395.1 - 0.48 11.2 8.9 9.1 7.2 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.13 KZN93396.1 - 8.2e-06 25.6 13.8 1.5e-05 24.7 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KZN93397.1 - 6.2e-57 193.3 0.1 2.4e-50 171.7 0.1 2.1 2 0 0 2 2 2 2 Amidase DUF823 PF05689.6 KZN93397.1 - 0.063 12.6 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) MFS_1 PF07690.11 KZN93398.1 - 9.1e-32 110.1 30.6 9.1e-32 110.1 21.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NTP_transf_5 PF14907.1 KZN93399.1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase AMP-binding PF00501.23 KZN93400.1 - 1.3e-87 293.8 0.0 2.1e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KZN93400.1 - 4.4e-74 249.1 0.0 1.6e-73 247.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KZN93400.1 - 1.4e-55 187.8 0.1 2.5e-53 180.4 0.0 3.1 3 1 0 3 3 3 1 KR domain adh_short PF00106.20 KZN93400.1 - 2.5e-51 173.9 0.0 1e-45 155.6 0.0 3.1 2 0 0 2 2 2 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 KZN93400.1 - 1.9e-50 172.0 0.0 4e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.15 KZN93400.1 - 1.4e-49 168.5 1.0 2.3e-49 167.9 0.7 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KZN93400.1 - 2.8e-45 154.7 0.0 4.4e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KZN93400.1 - 2.7e-40 137.8 0.0 3.1e-39 134.4 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KZN93400.1 - 1.3e-32 112.1 0.0 3e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 KZN93400.1 - 1.9e-22 79.8 0.0 5.6e-19 68.5 0.0 2.8 3 0 0 3 3 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KZN93400.1 - 7.7e-16 58.1 3.7 5.7e-09 36.1 0.1 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN93400.1 - 1.9e-09 36.6 0.0 3.6e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.7 KZN93400.1 - 1.2e-07 32.1 0.0 3.9e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KZN93400.1 - 5.4e-07 29.8 0.0 2.5e-06 27.6 0.0 2.2 2 0 0 2 2 1 1 HxxPF-repeated domain NAD_binding_10 PF13460.1 KZN93400.1 - 9.3e-07 29.0 0.0 5.6e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_23 PF13489.1 KZN93400.1 - 1.8e-06 27.7 0.0 1.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 KZN93400.1 - 6.5e-05 22.0 0.0 0.0002 20.4 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 KZN93400.1 - 0.0025 18.1 0.0 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain RmlD_sub_bind PF04321.12 KZN93400.1 - 0.0061 15.4 0.0 0.018 13.9 0.0 1.8 1 0 0 1 1 1 1 RmlD substrate binding domain Methyltransf_11 PF08241.7 KZN93400.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 KZN93400.1 - 0.03 13.2 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KZN93401.1 - 2e-08 33.8 0.0 3.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN93401.1 - 0.00012 21.8 1.2 0.02 14.6 0.0 3.4 3 1 1 4 4 4 2 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 KZN93403.1 - 3.2e-09 37.0 1.4 8.7e-09 35.5 0.3 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93403.1 - 3.6e-07 30.0 0.1 1.4e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KZN93403.1 - 2.1e-05 23.2 0.0 3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) MFS_1 PF07690.11 KZN93404.1 - 2.1e-44 151.7 48.7 1.6e-43 148.8 33.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN93404.1 - 4.3e-16 58.2 19.5 8.1e-16 57.3 13.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KZN93404.1 - 4.7e-15 55.1 17.1 4.7e-15 55.1 11.9 3.6 3 1 0 4 4 4 2 Sugar (and other) transporter EthD PF07110.6 KZN93405.1 - 7.1e-09 36.4 0.1 9.8e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 EthD domain Pkinase PF00069.20 KZN93406.1 - 8.3e-25 87.3 0.0 2.5e-24 85.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93406.1 - 2.5e-14 52.9 0.1 3.3e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KZN93406.1 - 0.0044 16.7 0.1 0.38 10.4 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KZN93406.1 - 0.15 11.3 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_1 PF00232.13 KZN93408.1 - 1.4e-158 527.8 0.0 1.7e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Kelch_4 PF13418.1 KZN93409.1 - 3e-26 90.9 8.8 3.6e-07 29.8 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KZN93409.1 - 1.9e-25 88.3 0.1 4.4e-05 23.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 KZN93409.1 - 1.3e-23 82.5 6.8 7.3e-08 32.3 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KZN93409.1 - 3.3e-21 74.4 1.3 3.8e-05 23.6 0.0 5.0 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KZN93409.1 - 6.6e-21 73.2 0.4 1.9e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 KZN93409.1 - 2e-19 68.8 0.1 3.2e-05 23.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 KZN93409.1 - 8.8e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 KZN93410.1 - 8.4e-24 82.5 18.4 2e-06 27.4 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KZN93410.1 - 6.5e-05 22.7 0.4 0.0051 16.5 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.8 KZN93411.1 - 6.2e-91 306.0 2.3 7.3e-91 305.8 1.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GET2 PF08690.5 KZN93411.1 - 0.12 11.6 0.3 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 PAT1 PF09770.4 KZN93411.1 - 2.1 6.4 26.7 3.7 5.6 18.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 KZN93412.1 - 1.2e-05 25.2 10.3 0.047 14.0 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN93412.1 - 0.00029 20.9 12.6 0.051 13.9 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KZN93412.1 - 0.00084 19.4 1.9 0.044 13.9 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KZN93412.1 - 0.0056 16.9 13.2 0.0083 16.3 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 KZN93412.1 - 0.044 13.4 0.3 0.08 12.5 0.2 1.3 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 KZN93412.1 - 8.8 6.3 6.4 0.51 10.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Toxin_20 PF08089.6 KZN93414.1 - 2.9 7.8 7.0 6.3 6.7 4.8 1.7 1 1 0 1 1 1 0 Huwentoxin-II family DUF2404 PF10296.4 KZN93415.1 - 0.0011 19.0 0.0 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Bap31 PF05529.7 KZN93416.1 - 8.7e-66 221.0 0.1 1.1e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 KZN93416.1 - 0.011 15.4 0.3 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cluap1 PF10234.4 KZN93416.1 - 0.013 14.7 0.6 0.017 14.3 0.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMF_TATA_bd PF12325.3 KZN93416.1 - 0.048 13.3 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.1 KZN93416.1 - 0.12 12.2 1.6 0.2 11.6 1.1 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 KZN93416.1 - 0.31 10.5 3.4 3.5 7.1 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator DUF1385 PF07136.6 KZN93416.1 - 2 7.4 5.8 2 7.4 3.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Peptidase_M24 PF00557.19 KZN93417.1 - 7e-21 74.7 0.0 8.2e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Dus PF01207.12 KZN93418.1 - 1.7e-38 132.2 0.0 1.2e-26 93.2 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KZN93418.1 - 0.0013 18.3 0.3 0.0013 18.3 0.2 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Metallophos PF00149.23 KZN93420.1 - 2.7e-06 26.9 1.7 1.9e-05 24.1 1.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN93420.1 - 0.0025 17.6 0.2 0.0058 16.4 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Senescence PF06911.7 KZN93421.1 - 1.6e-47 161.5 3.4 2.2e-47 161.0 2.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein DUF3082 PF11282.3 KZN93421.1 - 0.069 13.2 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) Pkinase PF00069.20 KZN93422.1 - 7.9e-64 215.3 0.0 1.2e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93422.1 - 1.3e-35 122.7 0.0 2.3e-33 115.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN93422.1 - 4.5e-05 22.5 0.0 0.03 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KZN93422.1 - 0.00036 19.9 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN93422.1 - 0.0016 18.1 0.1 0.0058 16.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN93422.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KZN93422.1 - 0.087 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ldh_2 PF02615.9 KZN93423.1 - 6.6e-96 320.9 0.0 7.6e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF4646 PF15496.1 KZN93423.1 - 0.075 13.0 0.1 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Fungal_trans PF04082.13 KZN93424.1 - 5.3e-11 41.8 2.0 8.1e-11 41.2 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KZN93425.1 - 7.7e-08 32.4 0.0 1.9e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN93425.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KZN93425.1 - 0.0079 15.1 0.0 0.028 13.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KZN93425.1 - 0.057 13.4 0.0 0.38 10.7 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding DUF1538 PF07556.6 KZN93426.1 - 0.013 14.6 0.7 0.017 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) SIMPL PF04402.9 KZN93427.1 - 2.4e-29 102.7 0.0 2.8e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Fungal_trans PF04082.13 KZN93428.1 - 4.1e-17 61.9 0.6 2.7e-13 49.3 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93428.1 - 1.5e-05 24.7 8.8 3.2e-05 23.7 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KZN93428.1 - 7.3 6.8 11.7 14 5.9 0.4 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Dabb PF07876.7 KZN93429.1 - 7.3e-15 55.1 0.1 1.1e-14 54.6 0.1 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain FAD_binding_3 PF01494.14 KZN93430.1 - 1.8e-74 250.9 0.0 3.2e-74 250.1 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KZN93430.1 - 0.0005 20.4 0.0 0.021 15.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN93430.1 - 0.0011 18.0 0.0 0.027 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN93430.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KZN93430.1 - 0.015 14.1 0.3 2.1 7.0 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.2 KZN93430.1 - 0.024 13.7 0.0 0.29 10.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KZN93430.1 - 0.044 13.6 0.0 0.35 10.7 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93430.1 - 0.09 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KZN93430.1 - 0.13 10.6 0.0 0.24 9.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KZN93431.1 - 1.2e-28 99.8 30.9 1.2e-28 99.8 21.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93431.1 - 2.4e-10 39.5 15.0 2.4e-10 39.5 10.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Acyl-CoA_dh_1 PF00441.19 KZN93433.1 - 1.9e-40 138.3 7.6 3.2e-40 137.6 5.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN93433.1 - 2e-27 96.0 2.4 7.7e-27 94.1 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KZN93433.1 - 1.1e-18 66.4 0.0 2.3e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN93433.1 - 1.3e-15 57.8 4.5 2.3e-15 57.0 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KZN93433.1 - 0.05 12.9 0.1 0.16 11.3 0.0 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Chitin_synth_1 PF01644.12 KZN93433.1 - 0.13 12.0 0.3 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Chitin synthase bZIP_1 PF00170.16 KZN93434.1 - 3e-06 27.1 6.4 1.6e-05 24.7 3.5 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KZN93434.1 - 0.0017 18.1 11.4 0.008 15.9 5.5 2.2 1 1 1 2 2 2 1 Basic region leucine zipper DUF4618 PF15397.1 KZN93434.1 - 0.018 14.4 2.9 0.025 13.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4094 PF13334.1 KZN93434.1 - 0.025 14.9 2.9 0.055 13.8 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Lzipper-MIP1 PF14389.1 KZN93434.1 - 0.062 13.4 1.6 4.8 7.3 0.1 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Guanylate_kin PF00625.16 KZN93434.1 - 0.08 12.3 1.4 0.12 11.8 1.0 1.2 1 0 0 1 1 1 0 Guanylate kinase DivIC PF04977.10 KZN93434.1 - 0.08 12.4 2.8 0.52 9.8 1.5 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KZN93434.1 - 0.085 13.2 1.8 0.12 12.6 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 KZN93434.1 - 0.13 12.2 5.1 0.19 11.6 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MbeD_MobD PF04899.7 KZN93434.1 - 0.19 11.6 3.0 3.2 7.7 0.0 2.5 1 1 1 2 2 2 0 MbeD/MobD like EAP30 PF04157.11 KZN93434.1 - 0.63 9.1 3.8 0.88 8.6 2.6 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Atg14 PF10186.4 KZN93434.1 - 2.2 7.1 6.8 3.6 6.4 4.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DEAD PF00270.24 KZN93435.1 - 4.9e-38 130.2 0.0 7.3e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN93435.1 - 3.3e-22 78.1 0.0 3e-21 75.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KZN93435.1 - 0.00036 20.2 1.4 0.00079 19.1 0.2 2.3 2 1 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KZN93435.1 - 0.0019 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KZN93435.1 - 0.044 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SecA_DEAD PF07517.9 KZN93435.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain GWT1 PF06423.7 KZN93436.1 - 1.2e-42 145.1 3.3 1.2e-42 145.1 2.3 2.1 2 1 1 3 3 3 1 GWT1 Amidase PF01425.16 KZN93437.1 - 5.1e-88 295.8 0.0 7.2e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 KZN93438.1 - 6.9e-09 35.2 0.0 1e-06 28.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93438.1 - 3.1e-05 23.1 0.0 8.8e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN93438.1 - 0.0092 15.7 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family PDEase_II PF02112.10 KZN93439.1 - 2.9e-56 190.7 0.0 8.2e-47 159.7 0.0 2.9 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KZN93439.1 - 1.9e-06 27.5 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KZN93439.1 - 4.3e-05 23.2 0.3 0.0001 21.9 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily SPRY PF00622.23 KZN93440.1 - 3.2e-19 69.2 0.0 5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF3611 PF12263.3 KZN93440.1 - 0.1 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Peptidase_M24 PF00557.19 KZN93441.1 - 1.9e-57 194.2 0.0 2.5e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KZN93441.1 - 1.6e-26 92.2 0.0 3.4e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HIG_1_N PF04588.8 KZN93442.1 - 5e-07 29.3 0.8 5e-07 29.3 0.6 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Iso_dh PF00180.15 KZN93443.1 - 7.4e-132 439.5 0.0 8.4e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase APC10 PF03256.11 KZN93444.1 - 1.5e-40 138.8 0.0 4.4e-40 137.3 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TPP_enzyme_N PF02776.13 KZN93446.1 - 1e-29 103.2 0.0 1.6e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KZN93446.1 - 2.1e-15 56.6 0.0 4.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KZN93446.1 - 1.9e-14 53.5 0.0 4.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.1 KZN93447.1 - 7.9e-30 104.3 1.4 9.5e-30 104.1 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN93447.1 - 6e-27 94.6 1.9 7.6e-27 94.2 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN93447.1 - 6.5e-14 51.9 1.2 8.9e-14 51.5 0.8 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 KZN93447.1 - 0.018 14.7 0.8 0.037 13.7 0.5 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KZN93447.1 - 0.022 14.4 1.3 0.045 13.3 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KZN93447.1 - 0.025 14.0 1.7 0.043 13.2 1.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 KZN93447.1 - 0.056 13.8 0.9 0.098 13.0 0.5 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pkinase PF00069.20 KZN93448.1 - 3.2e-49 167.4 0.0 1.8e-46 158.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93448.1 - 7.7e-33 113.6 0.0 2.8e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KZN93448.1 - 7.3e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KZN93448.1 - 0.0022 16.8 0.1 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KZN93448.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KZN93448.1 - 0.16 10.7 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Meth_synt_2 PF01717.13 KZN93449.1 - 1.6e-12 47.0 0.0 9e-11 41.3 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KZN93449.1 - 0.0029 16.9 0.0 0.054 12.7 0.0 2.7 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Pyr_redox_2 PF07992.9 KZN93450.1 - 7.6e-35 120.6 0.4 1.1e-34 120.1 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KZN93450.1 - 2.4e-32 111.2 0.1 4.7e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KZN93450.1 - 3e-13 49.9 0.2 3e-13 49.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN93450.1 - 0.002 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KZN93450.1 - 1.6 7.4 7.9 6.1 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 KZN93450.1 - 2.5 7.7 4.7 0.29 10.7 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amidohydro_2 PF04909.9 KZN93452.1 - 1.7e-21 77.0 0.0 2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 KZN93453.1 - 3.4e-78 263.2 15.8 3.9e-78 263.0 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93453.1 - 8.3e-16 57.6 19.5 8.3e-16 57.6 13.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KZN93454.1 - 7.1e-25 87.3 0.3 1.2e-24 86.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93454.1 - 1.8e-10 40.5 8.5 3e-10 39.8 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KZN93455.1 - 1.8e-43 147.9 0.1 6.4e-43 146.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN93455.1 - 2.5e-26 91.3 0.0 9.6e-26 89.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KZN93455.1 - 1.6e-06 26.7 0.0 1.6e-06 26.7 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) Acetyltransf_4 PF13420.1 KZN93456.1 - 4.3e-07 29.9 0.2 3.6e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Arf PF00025.16 KZN93457.1 - 2.1e-59 199.6 1.2 2.5e-59 199.4 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KZN93457.1 - 2.5e-09 36.3 1.8 0.00084 18.1 0.2 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KZN93457.1 - 1.5e-08 34.1 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KZN93457.1 - 1.9e-08 33.7 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KZN93457.1 - 2.5e-07 30.6 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KZN93457.1 - 2.9e-06 26.8 0.1 0.00043 19.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KZN93457.1 - 7e-06 25.3 0.0 9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KZN93457.1 - 0.00019 21.9 0.0 0.00027 21.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 KZN93457.1 - 0.0052 16.4 0.6 0.014 15.0 0.4 1.6 1 1 0 1 1 1 1 NACHT domain HCV_NS1 PF01560.12 KZN93457.1 - 0.0094 14.4 0.1 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 cobW PF02492.14 KZN93457.1 - 0.015 14.7 0.1 0.76 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KZN93457.1 - 0.058 12.8 0.2 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3650 PF12368.3 KZN93457.1 - 0.096 12.1 0.2 0.096 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) AAA_33 PF13671.1 KZN93457.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN93457.1 - 0.15 12.9 0.2 0.44 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KZN93457.1 - 0.15 11.1 0.2 0.37 9.8 0.1 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 KZN93458.1 - 3.7e-121 405.3 41.7 6.4e-73 246.4 13.6 6.1 5 2 1 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KZN93458.1 - 4.2e-10 39.1 0.0 0.00061 19.4 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 KZN93459.1 - 5.8e-86 288.2 0.1 8.4e-86 287.7 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KZN93459.1 - 8.4e-31 106.2 0.1 1.3e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Motilin_assoc PF04643.7 KZN93459.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide Arginase PF00491.16 KZN93460.1 - 1.1e-84 284.0 0.0 1.4e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KZN93460.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans_2 PF11951.3 KZN93461.1 - 3.4e-07 29.2 1.3 8.6e-07 27.8 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93461.1 - 4.4e-07 29.7 8.5 7.7e-07 28.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KZN93462.1 - 1.1e-60 204.9 7.2 1.6e-60 204.4 5.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF912 PF06024.7 KZN93462.1 - 0.16 12.0 0.2 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4131 PF13567.1 KZN93462.1 - 0.17 11.2 2.5 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-DHHC PF01529.15 KZN93462.1 - 8.6 5.7 8.8 6 6.2 0.1 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase Ank_2 PF12796.2 KZN93463.1 - 1.1e-54 182.7 3.2 7.1e-19 67.9 0.1 4.9 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KZN93463.1 - 1.9e-49 163.0 12.7 7.6e-08 31.7 0.0 8.3 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 KZN93463.1 - 1.1e-37 124.3 7.8 2.1e-05 24.3 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KZN93463.1 - 3.2e-37 126.2 13.4 2.3e-13 50.2 0.1 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN93463.1 - 9.1e-37 124.2 11.1 2e-07 31.0 0.1 7.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) CorA PF01544.13 KZN93463.1 - 1.5e-12 47.1 0.8 3.2e-12 46.0 0.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GLE1 PF07817.8 KZN93463.1 - 0.14 11.0 0.6 0.25 10.2 0.4 1.3 1 0 0 1 1 1 0 GLE1-like protein S6PP_C PF08472.5 KZN93464.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Aminotran_1_2 PF00155.16 KZN93465.1 - 8.4e-19 67.7 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KZN93465.1 - 0.0032 16.0 0.0 0.35 9.3 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.2 KZN93466.1 - 2.3e-92 309.1 18.4 1.9e-70 237.5 6.6 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KZN93466.1 - 1.1e-06 27.9 1.2 0.011 15.1 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 KZN93466.1 - 0.00046 19.4 1.5 0.0012 18.0 1.1 1.7 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 KZN93466.1 - 0.0063 16.2 6.1 0.0063 16.2 4.2 2.7 3 1 0 3 3 3 1 Right handed beta helix region Cation_efflux PF01545.16 KZN93467.1 - 3.6e-28 98.4 4.8 4.4e-28 98.1 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family Pro_isomerase PF00160.16 KZN93469.1 - 7.9e-44 149.5 0.7 9.1e-44 149.3 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_11 PF08241.7 KZN93470.1 - 2.8e-12 46.9 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93470.1 - 5e-12 45.6 0.0 6.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93470.1 - 1.1e-10 42.0 0.0 2.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN93470.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93470.1 - 3.7e-09 36.9 0.0 7.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93470.1 - 8.3e-08 32.5 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN93470.1 - 7.1e-05 22.2 0.0 0.00013 21.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KZN93470.1 - 0.00019 21.4 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KZN93470.1 - 0.0056 15.8 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KZN93470.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KZN93470.1 - 0.019 13.9 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 KZN93470.1 - 0.033 13.1 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 KZN93470.1 - 0.036 13.2 0.0 0.12 11.5 0.0 1.9 2 1 1 3 3 3 0 O-methyltransferase RrnaAD PF00398.15 KZN93470.1 - 0.042 12.8 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KZN93470.1 - 0.057 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 KZN93470.1 - 0.11 11.8 0.0 2.5 7.3 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Chitin_bind_3 PF03067.10 KZN93471.1 - 1.4e-19 71.0 1.4 2.3e-19 70.3 1.0 1.3 1 0 0 1 1 1 1 Chitin binding domain CDK2AP PF09806.4 KZN93471.1 - 3.5 7.8 9.2 27 4.9 4.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ADH_zinc_N_2 PF13602.1 KZN93472.1 - 6e-23 82.1 0.0 1.1e-22 81.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KZN93472.1 - 7.7e-16 57.8 0.1 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KZN93472.1 - 0.00075 19.5 0.7 0.0012 18.8 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_23 PF13489.1 KZN93473.1 - 2.2e-11 43.7 0.0 3.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93473.1 - 1.6e-07 31.8 0.0 8e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93473.1 - 0.005 17.2 0.0 0.019 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KZN93473.1 - 0.025 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GAT PF03127.9 KZN93474.1 - 5.6e-13 48.7 1.3 7.7e-13 48.2 0.0 1.8 3 0 0 3 3 3 1 GAT domain VHS PF00790.14 KZN93474.1 - 0.00025 20.7 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain HAD_2 PF13419.1 KZN93475.1 - 3.1e-33 115.4 0.0 3.7e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KZN93475.1 - 0.046 14.1 0.0 0.44 10.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.1 KZN93475.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 NAS PF03059.11 KZN93475.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein 2-Hacid_dh_C PF02826.14 KZN93476.1 - 7.9e-54 181.5 0.0 1.3e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L22 PF00237.14 KZN93476.1 - 1.9e-33 114.5 0.0 5.1e-33 113.1 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh PF00389.25 KZN93476.1 - 8.1e-19 67.4 0.0 1.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KZN93476.1 - 0.0042 16.9 0.7 0.0093 15.8 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 KZN93477.1 - 4.6e-29 100.3 0.7 8.5e-29 99.5 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93477.1 - 8.5e-16 57.6 0.3 1.5e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 KZN93477.1 - 0.00022 20.3 0.2 0.00032 19.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KZN93477.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KZN93477.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ThiF family adh_short PF00106.20 KZN93478.1 - 5.3e-28 98.0 0.4 7e-28 97.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93478.1 - 3.7e-18 66.1 0.1 4.7e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93478.1 - 4.3e-13 49.3 0.3 6.1e-13 48.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KZN93478.1 - 3.3e-07 30.0 0.1 5e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KZN93478.1 - 0.00096 18.1 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KZN93478.1 - 0.0073 16.0 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 KZN93478.1 - 0.012 14.5 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KZN93478.1 - 0.015 15.3 0.8 0.077 13.0 0.6 2.2 1 1 0 1 1 1 0 NADH(P)-binding ACT_7 PF13840.1 KZN93478.1 - 0.024 14.1 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 ACT domain Fungal_trans PF04082.13 KZN93479.1 - 1.7e-13 50.0 0.0 4.8e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93479.1 - 2.8e-05 23.9 10.8 4.9e-05 23.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KZN93480.1 - 2.4e-29 102.4 0.0 3.5e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93480.1 - 5.8e-18 65.5 0.0 8e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93480.1 - 1.9e-10 40.7 0.3 3e-10 40.0 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN93480.1 - 0.00011 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KZN93480.1 - 0.0003 20.5 0.3 0.00051 19.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KZN93480.1 - 0.0019 18.2 0.3 0.098 12.6 0.2 2.5 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KZN93480.1 - 0.0043 16.1 0.1 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 KZN93480.1 - 0.018 13.9 0.2 0.05 12.4 0.0 1.8 2 1 0 2 2 2 0 RmlD substrate binding domain Ferric_reduct PF01794.14 KZN93481.1 - 5.7e-22 78.1 7.0 1.6e-21 76.6 4.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KZN93481.1 - 2.1e-12 46.8 0.2 1.4e-06 28.0 0.1 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KZN93481.1 - 3e-12 46.7 0.0 1.2e-07 31.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain ABC2_membrane PF01061.19 KZN93482.1 - 5.9e-91 303.3 63.2 1.6e-49 167.9 15.1 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KZN93482.1 - 4e-40 135.6 7.8 2.1e-34 117.2 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KZN93482.1 - 3.5e-39 134.2 0.2 1.7e-18 67.1 0.0 3.3 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 KZN93482.1 - 7.9e-23 80.3 0.2 3.7e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KZN93482.1 - 5.8e-07 29.1 0.1 0.00042 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN93482.1 - 9.4e-07 28.1 0.2 6.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KZN93482.1 - 0.00025 20.9 0.1 0.018 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN93482.1 - 0.00044 19.7 1.2 0.019 14.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KZN93482.1 - 0.00051 19.1 16.7 0.00051 19.1 11.6 3.2 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.1 KZN93482.1 - 0.00079 19.4 0.5 0.0093 15.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KZN93482.1 - 0.0055 15.9 0.0 0.39 9.9 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KZN93482.1 - 0.0056 16.1 0.4 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KZN93482.1 - 0.0081 16.2 0.3 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KZN93482.1 - 0.014 15.3 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KZN93482.1 - 0.022 15.0 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KZN93482.1 - 0.025 15.4 0.0 0.35 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KZN93482.1 - 0.061 13.4 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 KZN93482.1 - 0.074 12.8 0.6 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KZN93482.1 - 0.077 12.6 3.7 3.1 7.4 0.1 3.1 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 KZN93482.1 - 0.078 13.4 0.0 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 KZN93482.1 - 0.089 12.2 0.2 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 KZN93482.1 - 0.093 12.9 0.1 26 5.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KZN93482.1 - 0.18 11.4 0.9 9.4 5.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 UBA_4 PF14555.1 KZN93484.1 - 1.4e-10 40.5 0.0 3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KZN93484.1 - 4.5e-09 36.2 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.20 KZN93486.1 - 2.5e-07 30.1 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93486.1 - 0.031 13.3 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Auxin_resp PF06507.8 KZN93486.1 - 0.074 12.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Auxin response factor Fasciclin PF02469.17 KZN93487.1 - 7.1e-42 142.4 0.0 3.3e-23 82.1 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Dioxygenase_C PF00775.16 KZN93488.1 - 6.2e-49 165.7 0.0 8.9e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KZN93488.1 - 1.9e-19 69.3 0.1 4.9e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus Zn_clus PF00172.13 KZN93489.1 - 0.049 13.5 9.9 0.12 12.3 6.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KZN93490.1 - 1.4e-20 72.5 0.3 1.8e-20 72.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KZN93490.1 - 0.0025 18.2 3.9 0.004 17.5 2.7 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Vps39_2 PF10367.4 KZN93491.1 - 1.4e-06 28.4 0.0 3.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KZN93491.1 - 0.03 14.3 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 KZN93491.1 - 0.21 10.9 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 CNH domain CASP_C PF08172.7 KZN93492.1 - 2.2e-88 295.4 4.4 2.2e-88 295.4 3.0 3.3 2 1 2 4 4 4 1 CASP C terminal Fib_alpha PF08702.5 KZN93492.1 - 8.7 6.4 28.1 15 5.6 0.0 4.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Serglycin PF04360.7 KZN93492.1 - 9.3 5.9 8.2 4.2 7.0 3.2 2.3 2 0 0 2 2 2 0 Serglycin DUF3455 PF11937.3 KZN93493.1 - 1.8e-45 155.1 0.1 2.3e-45 154.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 KZN93493.1 - 1.1e-23 82.8 0.3 2.4e-23 81.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.12 KZN93494.1 - 1.2e-106 354.7 0.0 1.5e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KZN93494.1 - 3.2e-06 26.8 0.0 5.3e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KZN93494.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.16 KZN93495.1 - 1e-21 77.4 0.0 1.4e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN93495.1 - 3.1e-12 45.7 0.0 3.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN93495.1 - 1.7e-07 31.4 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN93495.1 - 6.2e-06 25.3 0.0 0.00015 20.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KZN93495.1 - 6.7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KZN93495.1 - 7.4e-06 25.0 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KZN93495.1 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 KZN93495.1 - 0.0021 17.7 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 KZN93495.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KZN93495.1 - 0.0094 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KZN93495.1 - 0.0098 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Peptidase_M16 PF00675.15 KZN93496.1 - 6.6e-57 191.4 0.5 1.7e-56 190.0 0.2 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KZN93496.1 - 1.3e-42 145.5 0.0 2.4e-40 138.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Nol1_Nop2_Fmu PF01189.12 KZN93498.1 - 1.2e-30 106.9 0.0 1.5e-16 60.5 0.0 4.5 3 1 2 5 5 5 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KZN93498.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_35 PF01301.14 KZN93499.1 - 1e-94 317.5 0.0 2.4e-94 316.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KZN93499.1 - 1.6e-66 223.1 4.1 2.8e-66 222.3 2.9 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KZN93499.1 - 2.7e-52 175.7 6.9 2.5e-27 95.3 1.5 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KZN93499.1 - 8.9e-27 92.3 0.1 1.9e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 VIT1 PF01988.14 KZN93500.1 - 0.036 13.5 0.2 0.046 13.2 0.1 1.1 1 0 0 1 1 1 0 VIT family Glyco_transf_54 PF04666.8 KZN93502.1 - 2.6e-14 52.6 0.0 2.3e-13 49.5 0.0 2.1 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CYSTM PF12734.2 KZN93503.1 - 4.5e-11 42.6 4.5 4.5e-11 42.6 3.1 5.6 3 2 1 4 4 4 1 Cysteine-rich TM module stress tolerance RNA_pol_Rpb5_C PF01191.14 KZN93504.1 - 6e-36 121.8 0.2 9.9e-36 121.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KZN93504.1 - 1.6e-28 98.9 0.0 2.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KZN93504.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease Occludin_ELL PF07303.8 KZN93505.1 - 0.24 12.1 29.0 0.46 11.2 4.8 4.7 2 1 3 5 5 5 0 Occludin homology domain Reo_sigmaC PF04582.7 KZN93505.1 - 2.5 7.1 10.1 2.4 7.2 0.4 2.7 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Prominin PF05478.6 KZN93505.1 - 5.5 4.3 16.2 4.2 4.7 6.6 2.1 2 0 0 2 2 2 0 Prominin Aminotran_1_2 PF00155.16 KZN93507.1 - 4.2e-63 213.4 0.0 4.9e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KZN93507.1 - 0.035 12.7 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.15 KZN93507.1 - 0.064 11.5 0.0 0.12 10.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 KZN93508.1 - 4.5e-12 45.3 0.0 1.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93508.1 - 1.8e-10 40.5 16.7 3.8e-10 39.5 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KZN93509.1 - 1.6e-86 288.8 56.1 6.8e-46 156.0 13.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KZN93509.1 - 2.2e-37 126.8 0.4 7.2e-36 121.9 0.0 3.4 4 1 1 5 5 2 2 CDR ABC transporter ABC_tran PF00005.22 KZN93509.1 - 7.8e-33 113.6 0.0 2.7e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KZN93509.1 - 5.3e-15 55.2 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KZN93509.1 - 2.4e-11 43.2 40.0 3.2e-06 26.4 10.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KZN93509.1 - 1.2e-07 31.3 0.1 0.00051 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN93509.1 - 2.2e-07 30.1 0.1 9.9e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KZN93509.1 - 3.5e-05 23.8 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KZN93509.1 - 0.00012 22.0 0.1 0.026 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KZN93509.1 - 0.00024 20.5 0.3 0.03 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KZN93509.1 - 0.00047 20.4 0.2 0.085 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN93509.1 - 0.00064 19.4 0.4 0.44 10.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 KZN93509.1 - 0.00077 18.7 0.0 0.11 11.7 0.0 3.5 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KZN93509.1 - 0.00079 20.2 0.0 0.24 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KZN93509.1 - 0.0011 18.4 0.7 0.066 12.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KZN93509.1 - 0.0069 16.5 0.6 0.85 9.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KZN93509.1 - 0.012 15.6 1.0 1.8 8.4 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.1 KZN93509.1 - 0.013 15.4 0.5 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KZN93509.1 - 0.017 15.2 0.3 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KZN93509.1 - 0.022 14.4 2.4 3.1 7.4 0.3 2.8 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 KZN93509.1 - 0.11 12.9 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KZN93509.1 - 0.13 11.7 0.3 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KZN93509.1 - 0.14 12.1 0.0 10 6.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF1115 PF06544.7 KZN93510.1 - 6.8e-19 67.8 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Mmp37 PF09139.6 KZN93511.1 - 8.2e-137 455.6 0.0 1e-136 455.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 KZN93512.1 - 3.3e-44 149.1 5.2 5.9e-22 77.8 0.1 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 KZN93513.1 - 5.5e-08 32.7 0.5 9e-08 32.0 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN93513.1 - 4.9e-06 26.5 0.7 7.9e-06 25.8 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KZN93513.1 - 0.0048 17.1 0.7 0.0083 16.4 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KZN93513.1 - 0.052 13.6 0.5 0.15 12.2 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DDHD PF02862.12 KZN93513.1 - 3.3 7.4 7.4 16 5.1 0.1 2.1 2 0 0 2 2 2 0 DDHD domain F-box-like PF12937.2 KZN93514.1 - 0.0003 20.4 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN93514.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pyridox_oxidase PF01243.15 KZN93515.1 - 6e-07 29.3 0.0 9.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TFIID-18kDa PF02269.11 KZN93516.1 - 3.2e-27 94.1 0.1 2.9e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TP_methylase PF00590.15 KZN93517.1 - 1.2e-21 77.4 0.1 1.8e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MFS_1 PF07690.11 KZN93518.1 - 1.1e-14 53.9 13.8 1.1e-14 53.9 9.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily APH PF01636.18 KZN93520.1 - 1.3e-11 44.6 0.0 2.8e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93520.1 - 0.00026 20.6 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KZN93520.1 - 0.0022 17.2 0.0 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CRAL_TRIO PF00650.15 KZN93520.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.8 1 1 0 1 1 1 0 CRAL/TRIO domain Arylsulfotran_2 PF14269.1 KZN93521.1 - 3.2e-56 190.6 6.0 4.7e-56 190.1 4.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN93521.1 - 7.2e-19 67.6 6.3 6e-17 61.2 4.4 2.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_3 PF13469.1 KZN93522.1 - 0.0013 19.6 0.1 0.0023 18.9 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family Clat_adaptor_s PF01217.15 KZN93523.1 - 7.5e-56 187.7 2.0 8.7e-56 187.5 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.9 KZN93525.1 - 1.7e-49 167.3 2.1 1.1e-23 83.4 2.9 2.3 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DUF1289 PF06945.8 KZN93526.1 - 0.0012 18.2 0.3 0.0022 17.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Cys_Met_Meta_PP PF01053.15 KZN93527.1 - 2.1e-62 210.6 0.0 6.9e-62 208.9 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KZN93527.1 - 0.0058 15.6 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KZN93527.1 - 0.016 13.9 0.0 0.035 12.8 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KZN93527.1 - 0.096 11.7 0.1 0.97 8.4 0.0 2.2 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.3 KZN93528.1 - 1.1e-40 139.4 2.2 1.5e-40 139.0 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93528.1 - 5.9e-07 29.2 8.7 1.3e-06 28.2 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbJ PF01788.12 KZN93529.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PsbJ Pam17 PF08566.5 KZN93529.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 SUN PF03856.8 KZN93530.1 - 1e-82 277.1 8.0 1.5e-82 276.6 5.5 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Cutinase PF01083.17 KZN93531.1 - 7.3e-49 165.9 10.7 1e-48 165.4 7.4 1.2 1 0 0 1 1 1 1 Cutinase LCM PF04072.9 KZN93531.1 - 2e-19 69.8 0.0 3.1e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PE-PPE PF08237.6 KZN93531.1 - 0.00031 20.2 0.2 0.00056 19.3 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KZN93531.1 - 0.019 14.8 1.7 0.067 13.0 0.0 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.6 KZN93531.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 KZN93531.1 - 0.12 12.1 0.7 0.28 10.9 0.5 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RING_2 PF13639.1 KZN93532.1 - 1.4e-07 31.1 8.2 2.9e-07 30.2 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN93532.1 - 1.9e-07 31.0 2.0 4.9e-07 29.7 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KZN93532.1 - 4.8e-05 23.2 6.2 0.00012 21.9 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KZN93532.1 - 0.00011 21.9 2.2 0.00029 20.6 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KZN93532.1 - 0.00034 20.2 9.6 0.00067 19.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KZN93532.1 - 0.035 14.1 7.8 0.08 13.0 5.4 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 KZN93532.1 - 0.045 13.4 5.9 0.13 12.0 4.1 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 KZN93532.1 - 0.046 13.7 9.0 0.11 12.5 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN93532.1 - 0.16 11.6 6.2 0.29 10.8 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KZN93532.1 - 2.9 7.9 7.2 5.6 7.0 5.0 1.5 1 0 0 1 1 1 0 RING-like domain DUF1227 PF06777.6 KZN93533.1 - 8.5e-63 210.4 0.5 8.5e-63 210.4 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KZN93533.1 - 7.2e-52 175.2 0.2 1.2e-51 174.5 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KZN93533.1 - 3.2e-44 150.8 0.0 7.3e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 KZN93533.1 - 0.0017 17.2 0.0 0.0066 15.2 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KZN93533.1 - 0.0034 16.8 0.0 0.54 9.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN93533.1 - 0.0046 17.0 0.2 0.79 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KZN93533.1 - 0.012 15.4 0.0 0.061 13.1 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KZN93533.1 - 0.014 14.9 0.1 0.042 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KZN93533.1 - 0.045 12.9 0.1 3.7 6.7 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.7 KZN93533.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KZN93533.1 - 0.14 11.1 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Stomoxyn PF11585.3 KZN93533.1 - 0.2 11.4 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn ADH_N PF08240.7 KZN93534.1 - 2.8e-29 101.0 0.1 5.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93534.1 - 4.1e-18 65.1 0.0 6.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KZN93534.1 - 0.0034 16.9 0.2 0.0058 16.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RNA_pol_Rpb1_5 PF04998.12 KZN93535.1 - 6.7e-88 294.5 0.0 5.8e-87 291.4 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KZN93535.1 - 3.3e-62 209.3 1.5 4e-62 209.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KZN93535.1 - 2.6e-31 108.4 0.0 5.6e-30 104.1 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KZN93535.1 - 1.5e-29 103.3 1.7 2.8e-22 79.4 0.0 3.6 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KZN93535.1 - 3.7e-16 58.8 0.0 3.7e-16 58.8 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 PRP3 PF08572.5 KZN93536.1 - 1.3e-67 227.4 11.8 3.1e-67 226.2 8.2 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KZN93536.1 - 8.1e-38 128.9 0.0 1.9e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Gar1 PF04410.9 KZN93537.1 - 6.9e-46 155.5 0.6 6.9e-46 155.5 0.4 2.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 KZN93538.1 - 1.6e-83 281.0 20.1 1.9e-83 280.8 13.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.3 KZN93539.1 - 1.9e-84 282.9 0.0 2.3e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Exo5 PF09810.4 KZN93540.1 - 2.3e-128 427.9 0.0 2.9e-128 427.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KZN93540.1 - 0.0068 15.8 1.6 0.9 8.8 1.1 2.9 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 KZN93541.1 - 3e-18 65.1 0.7 3e-18 65.1 0.5 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KZN93542.1 - 1.4e-38 132.5 47.8 3.5e-38 131.2 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.19 KZN93543.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KZN93543.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KZN93543.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KZN93543.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KZN93544.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KZN93544.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KZN93544.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KZN93544.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KZN93544.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KZN93544.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BTB PF00651.26 KZN93545.1 - 2.6e-11 43.4 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.21 KZN93546.1 - 6.5e-09 35.6 18.4 5.7e-05 23.2 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN93546.1 - 7.9e-08 32.1 18.2 0.00065 19.8 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Ig_2 PF13895.1 KZN93546.1 - 0.02 15.0 0.5 0.053 13.6 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin domain zf-H2C2_2 PF13465.1 KZN93546.1 - 0.13 12.5 14.4 1.2 9.5 1.1 4.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 KZN93546.1 - 0.31 11.1 7.2 3.9 7.6 1.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 KZN93546.1 - 0.37 10.3 1.9 1.5 8.3 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-BED PF02892.10 KZN93546.1 - 0.95 9.2 7.5 0.098 12.4 1.8 1.9 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 KZN93547.1 - 0.00027 21.0 21.9 0.046 14.0 1.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KZN93547.1 - 0.0024 18.0 24.4 0.0057 16.9 1.7 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Rpr2 PF04032.11 KZN93547.1 - 0.058 13.2 0.3 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2841 PF11001.3 KZN93548.1 - 7.2e-44 148.6 0.7 1.1e-43 148.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Sulfotransfer_3 PF13469.1 KZN93549.1 - 4.3e-08 34.2 3.3 1.8e-07 32.2 2.2 2.0 1 1 0 1 1 1 1 Sulfotransferase family DUF4389 PF14333.1 KZN93550.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4389) OAD_gamma PF04277.8 KZN93550.1 - 0.46 10.9 2.2 1.1 9.6 1.5 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain p450 PF00067.17 KZN93551.1 - 1.4e-62 211.7 0.0 1.9e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPSP_synthase PF00275.15 KZN93552.1 - 3e-127 424.5 0.0 6.9e-127 423.3 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KZN93552.1 - 5.7e-96 320.4 0.0 1e-95 319.5 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KZN93552.1 - 7e-62 209.0 0.0 1.2e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KZN93552.1 - 4.8e-41 140.2 0.0 2.7e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KZN93552.1 - 7.4e-24 83.6 0.0 1.7e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KZN93552.1 - 6.8e-11 42.4 0.0 3.6e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KZN93552.1 - 5.2e-07 29.2 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KZN93552.1 - 1.4e-05 25.8 0.0 6.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN93552.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KZN93552.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN93552.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3489 PF11994.3 KZN93552.1 - 0.13 12.2 0.1 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) AAA_14 PF13173.1 KZN93552.1 - 0.15 11.9 0.0 0.5 10.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KZN93552.1 - 0.16 12.1 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KZN93552.1 - 0.27 10.0 0.0 0.47 9.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2685 PF10886.3 KZN93553.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Uso1_p115_head PF04869.9 KZN93554.1 - 1.5e-106 355.7 0.0 4e-106 354.2 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region TMF_DNA_bd PF12329.3 KZN93554.1 - 3.7e-14 52.2 40.9 8.8e-10 38.2 6.7 10.2 2 2 7 10 10 8 3 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.8 KZN93554.1 - 4.2e-07 29.9 26.2 4.2e-07 29.9 18.1 5.6 1 1 4 6 6 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 KZN93554.1 - 2.2e-06 27.3 78.8 9.2e-05 22.0 25.8 5.1 1 1 2 3 3 3 3 Intermediate filament protein AAA_13 PF13166.1 KZN93554.1 - 6.4e-06 24.9 29.9 6.4e-06 24.9 20.7 3.2 1 1 2 3 3 3 2 AAA domain DUF3584 PF12128.3 KZN93554.1 - 0.00011 19.6 53.1 0.00011 19.6 36.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KZN93554.1 - 0.00015 19.6 44.4 0.00015 19.6 30.8 2.9 1 1 1 2 2 2 1 Myosin tail CENP-F_leu_zip PF10473.4 KZN93554.1 - 0.00021 21.1 81.6 0.0013 18.6 15.4 5.3 2 1 3 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KZN93554.1 - 0.00035 19.8 5.5 0.00035 19.8 3.8 4.7 2 1 4 6 6 6 3 Reovirus sigma C capsid protein MAD PF05557.8 KZN93554.1 - 0.00037 18.7 6.3 0.00037 18.7 4.4 3.3 1 1 2 3 3 3 1 Mitotic checkpoint protein Surfac_D-trimer PF09006.6 KZN93554.1 - 0.0057 16.3 23.5 1.1 9.0 0.0 8.3 6 2 3 9 9 9 1 Lung surfactant protein D coiled-coil trimerisation Tropomyosin_1 PF12718.2 KZN93554.1 - 0.097 12.5 98.7 0.2 11.4 8.0 6.5 1 1 4 5 5 4 0 Tropomyosin like DUF869 PF05911.6 KZN93554.1 - 0.15 10.2 71.3 0.22 9.7 36.4 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Tup_N PF08581.5 KZN93554.1 - 0.17 12.0 0.0 0.17 12.0 0.0 7.2 2 1 5 8 8 6 0 Tup N-terminal Tropomyosin PF00261.15 KZN93554.1 - 0.91 8.5 88.5 0.051 12.6 7.6 6.2 1 1 5 6 6 6 0 Tropomyosin WEMBL PF05701.6 KZN93554.1 - 1.2 7.5 87.8 0.14 10.5 43.5 2.3 1 1 1 2 2 2 0 Weak chloroplast movement under blue light gpW PF02831.10 KZN93554.1 - 1.4 8.5 10.3 15 5.2 0.0 6.3 6 1 1 7 7 6 0 gpW Nuc_N PF14448.1 KZN93554.1 - 1.5 8.3 10.1 23 4.6 0.1 5.2 4 1 1 5 5 5 0 Nuclease N terminal IncA PF04156.9 KZN93554.1 - 3.8 7.0 86.0 1.3 8.5 2.2 5.8 1 1 2 3 3 2 0 IncA protein Fib_alpha PF08702.5 KZN93554.1 - 4.3 7.4 59.5 0.44 10.6 0.7 5.6 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 KZN93554.1 - 8.4 6.2 50.3 1.3 8.8 1.5 6.3 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) XRN_N PF03159.13 KZN93555.1 - 7.1e-106 352.9 1.1 2.4e-105 351.1 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 KZN93555.1 - 0.06 13.3 2.4 0.12 12.3 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle tRNA-synt_1 PF00133.17 KZN93556.1 - 1.4e-220 733.3 0.0 2.1e-220 732.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KZN93556.1 - 1.2e-24 86.7 0.0 3.4e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KZN93556.1 - 6.4e-19 67.8 0.2 1.5e-08 33.7 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Cmc1 PF08583.5 KZN93557.1 - 0.0037 16.9 2.1 0.0047 16.6 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KZN93557.1 - 0.0085 16.0 0.7 0.011 15.6 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 KZN93557.1 - 0.19 11.7 2.2 1.2 9.1 1.3 2.0 1 1 1 2 2 2 0 CHCH domain Sfi1 PF08457.5 KZN93558.1 - 7e-180 599.2 79.3 7e-180 599.2 54.9 2.0 1 1 0 1 1 1 1 Sfi1 spindle body protein Rav1p_C PF12234.3 KZN93559.1 - 3.1e-273 907.7 0.0 4e-273 907.3 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KZN93559.1 - 3.1e-06 26.8 1.5 0.39 10.6 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat p450 PF00067.17 KZN93560.1 - 2e-58 198.0 0.0 2.4e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tir_receptor_C PF07489.6 KZN93561.1 - 0.0035 17.1 2.1 0.0035 17.1 1.4 1.8 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus SGL PF08450.7 KZN93563.1 - 2e-25 89.5 0.6 4.3e-25 88.5 0.4 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KZN93563.1 - 1.8e-05 24.6 0.0 5.2e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 KZN93563.1 - 2.3e-05 24.2 0.1 0.001 19.0 0.0 2.6 1 1 0 2 2 2 1 Arylesterase NHL PF01436.16 KZN93563.1 - 0.046 13.7 3.1 0.55 10.3 0.0 3.5 3 0 0 3 3 3 0 NHL repeat Herpes_gE PF02480.11 KZN93564.1 - 9.6e-05 20.8 0.0 9.6e-05 20.8 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Glycophorin_A PF01102.13 KZN93564.1 - 0.01 15.5 0.2 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 Glycophorin A SKG6 PF08693.5 KZN93564.1 - 0.036 13.3 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Yip1 PF04893.12 KZN93564.1 - 0.046 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain p450 PF00067.17 KZN93565.1 - 1.9e-74 250.8 0.0 2.2e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mcp5_PH PF12814.2 KZN93567.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology AAA_16 PF13191.1 KZN93568.1 - 9.2e-10 38.7 5.3 3.6e-08 33.6 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain TPR_7 PF13176.1 KZN93568.1 - 0.00032 20.2 6.7 11 6.0 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.7 KZN93568.1 - 0.0015 18.2 0.2 0.41 10.2 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KZN93568.1 - 0.0071 16.4 3.8 0.024 14.7 0.0 4.0 3 1 0 4 4 4 1 AAA domain TPR_2 PF07719.12 KZN93568.1 - 0.011 15.5 12.9 2.7 8.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KZN93568.1 - 0.013 15.7 12.5 1.8 8.9 0.3 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Fork_head PF00250.13 KZN93568.1 - 0.027 14.4 0.1 0.12 12.4 0.1 2.1 1 0 0 1 1 1 0 Fork head domain AAA_19 PF13245.1 KZN93568.1 - 0.04 13.6 0.0 0.2 11.4 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain PPR PF01535.15 KZN93568.1 - 0.16 12.0 0.0 30 4.8 0.0 4.3 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.1 KZN93568.1 - 0.34 10.9 23.1 6.6 6.8 0.0 9.1 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93568.1 - 3.1 8.6 21.4 36 5.3 0.0 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Pkinase PF00069.20 KZN93569.1 - 5e-14 52.0 0.0 1.2e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93569.1 - 4.3e-10 39.1 0.0 2.9e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KZN93569.1 - 0.086 11.8 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPT PF03151.11 KZN93570.1 - 2.4e-17 62.9 12.3 2.4e-17 62.9 8.5 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family Glyco_transf_25 PF01755.12 KZN93570.1 - 4.7e-09 36.1 0.0 7.2e-08 32.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) EamA PF00892.15 KZN93570.1 - 1.5e-05 25.0 7.8 1.5e-05 25.0 5.4 3.2 2 1 2 4 4 4 1 EamA-like transporter family MFS_1 PF07690.11 KZN93571.1 - 1.8e-39 135.4 31.2 1.8e-39 135.4 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93571.1 - 5.1e-14 51.7 29.6 8e-14 51.0 20.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Kin17_mid PF10357.4 KZN93572.1 - 8.5e-49 164.4 1.0 1.6e-48 163.5 0.7 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KZN93572.1 - 0.007 16.5 3.5 0.016 15.3 2.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN93572.1 - 0.016 15.3 2.9 0.016 15.3 2.0 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KZN93572.1 - 0.032 14.3 2.3 0.079 13.0 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SNAPc_SNAP43 PF09808.4 KZN93572.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Actin PF00022.14 KZN93573.1 - 5.1e-20 71.2 0.0 1.1e-17 63.5 0.0 3.0 2 1 0 2 2 2 2 Actin CBFD_NFYB_HMF PF00808.18 KZN93574.1 - 4.5e-18 65.0 0.3 8.2e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KZN93574.1 - 3.8e-05 23.7 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KZN93574.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated SPOB_ab PF14682.1 KZN93574.1 - 0.061 13.1 0.6 0.084 12.6 0.4 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Mrr_N PF14338.1 KZN93574.1 - 0.089 12.8 1.5 0.11 12.5 0.4 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain YolD PF08863.5 KZN93574.1 - 3 7.7 5.1 3.1 7.7 2.8 1.6 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.20 KZN93575.1 - 4.9e-33 114.4 1.5 6.1e-33 114.0 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KZN93575.1 - 2.7e-14 53.2 1.2 4.3e-14 52.5 0.5 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KZN93575.1 - 1.9e-11 44.2 0.0 2.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KZN93575.1 - 7.4e-06 26.0 0.2 1.2e-05 25.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN93575.1 - 0.0016 17.9 0.1 0.005 16.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KZN93575.1 - 0.0026 17.0 0.5 0.0051 16.1 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 KZN93575.1 - 0.023 14.7 0.1 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KZN93575.1 - 0.075 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 KZN93575.1 - 0.12 11.0 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 KZN93575.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DAO PF01266.19 KZN93576.1 - 1.6e-32 112.8 0.1 2.3e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN93576.1 - 0.0011 19.3 0.1 0.34 11.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN93576.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3354 PF11834.3 KZN93576.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) Mqo PF06039.10 KZN93576.1 - 0.15 10.1 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) zf-CCCH PF00642.19 KZN93577.1 - 7.4e-09 35.0 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KZN93577.1 - 0.0061 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KZN93577.1 - 0.054 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 KZN93577.1 - 1.3 8.8 5.8 0.71 9.7 0.4 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 SMC_Nse1 PF07574.8 KZN93578.1 - 9.1e-35 120.0 0.0 1.2e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KZN93578.1 - 1.1e-12 47.7 10.9 1.8e-12 47.0 7.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-Apc11 PF12861.2 KZN93578.1 - 0.0016 18.2 2.3 0.0027 17.5 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 KZN93578.1 - 0.0038 16.9 3.8 0.0038 16.9 2.6 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 KZN93578.1 - 0.0041 16.9 8.1 0.0072 16.1 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN93578.1 - 0.046 13.8 3.4 0.087 12.9 2.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 KZN93578.1 - 0.17 11.8 6.5 0.48 10.4 4.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 KZN93578.1 - 0.26 10.9 9.8 0.47 10.1 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.5 KZN93578.1 - 0.56 10.8 2.7 0.38 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Glyco_hydro_65m PF03632.10 KZN93579.1 - 2.8e-85 286.2 3.4 1.3e-84 284.0 2.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KZN93579.1 - 5.1e-51 173.4 0.0 1.1e-50 172.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 KZN93579.1 - 1.9e-07 31.0 0.1 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.14 KZN93580.1 - 2.8e-160 533.1 0.4 3.8e-160 532.7 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KZN93580.1 - 2.8e-19 68.7 0.0 6.8e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.19 KZN93581.1 - 2.7e-08 33.7 0.1 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN93581.1 - 3.7e-06 26.9 0.0 5.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN93581.1 - 3.2e-05 24.0 0.1 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN93581.1 - 0.037 13.8 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cupin_2 PF07883.6 KZN93582.1 - 1.7e-09 37.0 0.2 5.7e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 KZN93582.1 - 0.021 14.4 0.0 7 6.2 0.0 2.4 2 0 0 2 2 2 0 Cupin Na_Ca_ex PF01699.19 KZN93583.1 - 2.7e-25 88.5 31.7 1.8e-15 56.7 7.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KZN93583.1 - 0.86 9.4 5.0 9.6 6.1 0.3 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DAO PF01266.19 KZN93586.1 - 1.4e-50 172.2 0.0 1.9e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN93586.1 - 3.9e-07 30.0 0.0 1.3e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN93586.1 - 6.6e-07 29.4 0.0 0.018 14.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KZN93586.1 - 1.8e-05 24.9 0.0 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN93586.1 - 0.00012 20.6 0.0 0.099 11.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 KZN93586.1 - 0.00087 19.6 0.0 0.042 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KZN93586.1 - 0.0038 17.3 0.0 0.0096 16.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 KZN93586.1 - 0.0065 15.1 0.0 0.095 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.13 KZN93586.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KZN93586.1 - 0.027 13.8 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KZN93586.1 - 0.03 13.4 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 KZN93586.1 - 0.038 12.8 0.0 0.075 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KZN93586.1 - 0.045 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KZN93586.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KZN93586.1 - 0.069 11.9 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.13 KZN93587.1 - 2e-13 49.8 0.0 4.3e-13 48.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.14 KZN93588.1 - 1.1e-23 83.9 2.5 4.1e-18 65.8 0.0 2.7 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KZN93588.1 - 8.6e-15 54.1 0.0 1.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.13 KZN93589.1 - 2.8e-10 39.4 1.6 5.3e-10 38.6 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93589.1 - 1.2e-09 37.8 9.1 3.1e-09 36.5 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KZN93590.1 - 5.4e-59 199.4 11.4 5.4e-59 199.4 7.9 1.7 1 1 1 2 2 2 1 RTA1 like protein PalH PF08733.5 KZN93590.1 - 0.82 8.4 14.6 0.12 11.1 3.0 2.1 1 1 0 2 2 2 0 PalH/RIM21 Vma12 PF11712.3 KZN93590.1 - 2.6 7.7 4.5 6.4 6.4 0.3 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4131 PF13567.1 KZN93590.1 - 4.3 6.7 7.3 2.5 7.4 1.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ATP-synt_8 PF00895.15 KZN93590.1 - 4.9 7.4 0.0 4.9 7.4 0.0 3.7 5 0 0 5 5 5 0 ATP synthase protein 8 RTA1 PF04479.8 KZN93592.1 - 1.2e-60 204.7 8.6 2e-60 204.1 6.0 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.5 KZN93592.1 - 8.6 5.0 10.1 0.28 9.9 0.3 2.4 2 1 0 2 2 2 0 PalH/RIM21 Glyco_hydro_10 PF00331.15 KZN93593.1 - 6.3e-71 239.0 0.0 7.5e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KZN93593.1 - 0.0059 15.7 0.1 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_transf_28 PF03033.15 KZN93594.1 - 2.7e-22 79.0 0.0 9.1e-22 77.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KZN93594.1 - 0.0027 16.3 0.1 0.0071 14.9 0.1 1.6 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KZN93594.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Oxidored_FMN PF00724.15 KZN93595.1 - 3.5e-92 309.0 0.0 4e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2672 PF10878.3 KZN93595.1 - 0.0075 15.9 0.1 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2672) AP_endonuc_2 PF01261.19 KZN93595.1 - 0.028 13.7 0.0 2.5 7.3 0.0 2.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Ribonuc_L-PSP PF01042.16 KZN93596.1 - 3.3e-19 68.8 0.0 4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 KZN93597.1 - 3.4e-30 104.9 35.6 3.4e-30 104.9 24.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1146 PF06612.6 KZN93597.1 - 0.15 12.0 3.6 2.2 8.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) DUF202 PF02656.10 KZN93597.1 - 2.5 8.3 7.5 15 5.8 0.2 4.6 4 2 0 4 4 4 0 Domain of unknown function (DUF202) AA_permease_2 PF13520.1 KZN93598.1 - 2.7e-48 164.5 48.1 3.4e-48 164.2 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN93598.1 - 2.4e-19 69.0 40.4 3.7e-19 68.4 28.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pox_P21 PF05313.7 KZN93598.1 - 0.15 11.3 4.0 0.28 10.4 1.6 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Arylsulfotran_2 PF14269.1 KZN93599.1 - 7e-56 189.5 3.2 9.4e-56 189.1 2.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KZN93599.1 - 5.4e-14 51.5 1.2 1e-13 50.6 0.8 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) TMEM52 PF14979.1 KZN93599.1 - 0.22 11.4 0.8 0.39 10.5 0.5 1.3 1 0 0 1 1 1 0 Transmembrane 52 p450 PF00067.17 KZN93600.1 - 8.1e-77 258.6 0.0 1e-76 258.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 KZN93601.1 - 1.6e-07 31.3 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family TilS PF09179.6 KZN93602.1 - 0.15 12.0 0.8 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 TilS substrate binding domain DUF2007 PF09413.5 KZN93606.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) AAA_12 PF13087.1 KZN93607.1 - 1.6e-23 83.1 0.0 3.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KZN93607.1 - 2.6e-07 30.4 0.0 5.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KZN93607.1 - 0.00016 21.7 0.0 0.00046 20.2 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KZN93607.1 - 0.0032 17.1 0.2 0.0032 17.1 0.1 2.8 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN93607.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KZN93607.1 - 0.014 16.2 0.0 0.094 13.5 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KZN93607.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF3176 PF11374.3 KZN93608.1 - 2.2e-33 114.4 0.5 7.4e-33 112.7 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF4381 PF14316.1 KZN93609.1 - 0.039 14.0 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4366 PF14283.1 KZN93609.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Med21 PF11221.3 KZN93610.1 - 0.058 13.3 1.9 0.25 11.3 1.3 2.0 2 1 0 2 2 2 0 Subunit 21 of Mediator complex Asparaginase_II PF06089.7 KZN93611.1 - 1.6e-106 355.7 0.4 1.8e-106 355.5 0.3 1.0 1 0 0 1 1 1 1 L-asparaginase II DUF1212 PF06738.7 KZN93612.1 - 6.3e-56 188.8 14.9 4.4e-51 173.0 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KZN93612.1 - 4.6e-27 94.5 11.0 4.6e-27 94.5 7.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) FSH1 PF03959.8 KZN93613.1 - 3.5e-29 101.7 0.0 4.1e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KZN93613.1 - 0.00039 20.1 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family KR PF08659.5 KZN93614.1 - 6.1e-60 201.9 0.0 2.5e-59 199.9 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 KZN93614.1 - 4.3e-55 186.9 0.0 9.1e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KZN93614.1 - 3.8e-50 171.0 0.1 1.2e-48 166.0 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KZN93614.1 - 1.7e-44 151.6 0.0 9.7e-44 149.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ketoacyl-synt PF00109.21 KZN93614.1 - 2.5e-40 138.5 1.6 4.7e-40 137.6 1.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KZN93614.1 - 2.8e-39 133.6 0.0 1.2e-38 131.6 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 KZN93614.1 - 2.2e-08 33.9 0.0 4.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93614.1 - 1e-07 32.3 0.0 3e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93614.1 - 4.1e-06 27.1 0.0 1.5e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KZN93614.1 - 5.2e-05 22.3 0.2 0.00011 21.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KZN93614.1 - 6.2e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KZN93614.1 - 0.001 19.2 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KZN93614.1 - 0.0022 18.5 0.0 0.0076 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93614.1 - 0.0075 15.8 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN93614.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 KZN93614.1 - 0.017 14.7 0.8 0.22 11.2 0.2 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ATP-synt_Eps PF04627.8 KZN93614.1 - 0.043 13.3 0.2 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain Polysacc_synt_2 PF02719.10 KZN93614.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC2_membrane PF01061.19 KZN93615.1 - 4.8e-90 300.3 46.9 1.9e-47 161.1 12.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KZN93615.1 - 4.6e-40 137.0 0.0 7.3e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KZN93615.1 - 7e-31 105.9 9.1 2e-30 104.4 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KZN93615.1 - 5e-10 38.9 40.1 8.6e-06 25.0 13.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KZN93615.1 - 1.2e-07 31.2 0.1 0.00084 18.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KZN93615.1 - 7e-06 26.2 0.1 0.11 12.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KZN93615.1 - 4.9e-05 23.2 0.0 0.44 10.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KZN93615.1 - 0.00052 20.8 0.0 0.56 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KZN93615.1 - 0.00065 19.6 0.8 0.32 10.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KZN93615.1 - 0.00094 18.6 1.3 0.32 10.4 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 KZN93615.1 - 0.001 18.5 1.4 0.077 12.5 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KZN93615.1 - 0.0011 19.0 0.3 0.4 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KZN93615.1 - 0.0016 17.6 0.1 0.0088 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KZN93615.1 - 0.0028 17.9 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KZN93615.1 - 0.0031 17.1 1.0 1.6 8.3 0.1 2.5 2 0 0 2 2 2 2 NACHT domain ABC_trans_N PF14510.1 KZN93615.1 - 0.0051 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_19 PF13245.1 KZN93615.1 - 0.0082 15.8 0.1 2.8 7.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain PduV-EutP PF10662.4 KZN93615.1 - 0.022 14.2 1.3 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KZN93615.1 - 0.03 14.5 0.0 12 6.1 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KZN93615.1 - 0.059 13.3 0.0 0.66 9.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 KZN93615.1 - 0.073 12.6 1.1 5.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KZN93615.1 - 0.1 13.1 0.0 3.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 KZN93615.1 - 0.11 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase MFS_1 PF07690.11 KZN93616.1 - 2.8e-33 115.1 23.0 6.2e-33 113.9 16.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily IATP PF04568.7 KZN93617.1 - 1e-15 57.5 0.1 1.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NinG PF05766.7 KZN93617.1 - 0.062 13.0 1.0 0.076 12.7 0.7 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF3677 PF12432.3 KZN93617.1 - 0.09 13.2 0.1 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) MFS_1 PF07690.11 KZN93618.1 - 4.6e-32 111.0 57.7 2e-29 102.4 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93618.1 - 8.2e-05 21.3 41.4 0.023 13.3 10.4 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KZN93618.1 - 0.00062 19.5 0.9 0.34 10.7 0.1 3.0 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.1 KZN93618.1 - 0.00069 18.1 14.6 0.00069 18.1 10.1 3.1 1 1 3 4 4 4 4 MFS/sugar transport protein Zn_clus PF00172.13 KZN93621.1 - 1e-05 25.3 12.7 2.1e-05 24.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN93621.1 - 0.00011 20.9 0.0 0.00057 18.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Halo_GVPC PF05465.8 KZN93621.1 - 0.43 10.5 0.1 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Abhydrolase_6 PF12697.2 KZN93622.1 - 4e-09 36.6 0.0 4.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KZN93622.1 - 1.6e-07 30.8 0.0 3.3e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 KZN93622.1 - 9.9e-06 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN93622.1 - 0.00021 20.9 0.0 0.00072 19.1 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KZN93622.1 - 0.019 14.5 0.0 0.39 10.2 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.3 KZN93622.1 - 0.028 13.7 0.1 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF900 PF05990.7 KZN93622.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 KZN93622.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein HCV_env PF01539.12 KZN93622.1 - 0.14 11.5 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Hce2 PF14856.1 KZN93623.1 - 3.6e-21 74.8 0.3 1.3e-20 73.0 0.2 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor tRNA_synt_1c_R2 PF04557.10 KZN93624.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SSP160 PF06933.6 KZN93624.1 - 2.2 6.1 10.4 2.2 6.1 7.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IncA PF04156.9 KZN93625.1 - 0.14 11.7 2.2 0.28 10.7 1.5 1.4 1 0 0 1 1 1 0 IncA protein Abhydrolase_4 PF08386.5 KZN93626.1 - 7.1e-27 93.3 0.0 1.7e-26 92.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KZN93626.1 - 7.8e-14 51.7 0.0 7.1e-09 35.5 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN93626.1 - 8.7e-08 32.3 0.5 5.3e-06 26.4 0.2 3.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93626.1 - 0.002 17.8 0.0 0.02 14.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aldolase_II PF00596.16 KZN93627.1 - 2.5e-47 160.8 0.1 3.3e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Rab5-bind PF09311.6 KZN93631.1 - 0.0018 18.1 0.1 0.0022 17.9 0.1 1.1 1 0 0 1 1 1 1 Rabaptin-like protein adh_short PF00106.20 KZN93632.1 - 6e-23 81.5 0.5 5.5e-15 55.6 0.2 2.2 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93632.1 - 2.5e-09 37.2 0.1 2.6e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93632.1 - 1.2e-07 31.5 0.3 5.1e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KZN93632.1 - 0.00044 20.3 0.2 0.46 10.4 0.0 2.4 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 KZN93632.1 - 0.012 15.0 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KZN93632.1 - 0.058 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KZN93632.1 - 0.13 12.0 0.4 0.43 10.3 0.4 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ldh_1_N PF00056.18 KZN93632.1 - 0.19 11.5 0.7 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF389 PF04087.9 KZN93632.1 - 4.3 7.2 6.1 0.93 9.4 0.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF389) Abhydrolase_3 PF07859.8 KZN93633.1 - 1.5e-52 178.2 0.0 1.9e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KZN93633.1 - 8.4e-08 31.3 0.0 2.8e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KZN93633.1 - 0.00016 20.4 0.0 0.00022 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KZN93633.1 - 0.0006 19.5 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN93633.1 - 0.00066 18.9 0.0 0.0082 15.3 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KZN93633.1 - 0.0093 14.4 0.0 0.016 13.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KZN93633.1 - 0.14 11.4 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Cyclase PF04199.8 KZN93634.1 - 6.9e-13 48.6 0.0 9.8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.1 KZN93635.1 - 5.1e-23 82.2 0.0 9.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN93635.1 - 2.8e-12 45.6 0.0 1.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KZN93635.1 - 9.9e-12 45.1 0.0 1.2e-10 41.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KZN93635.1 - 8.4e-11 41.3 0.0 1.1e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KZN93635.1 - 3.8e-10 39.6 0.0 1.3e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KZN93635.1 - 2.5e-05 23.3 0.1 0.01 14.7 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 KZN93635.1 - 8.3e-05 21.6 1.4 0.0077 15.1 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KZN93635.1 - 8.9e-05 22.8 0.8 0.01 16.2 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93635.1 - 0.00025 20.2 0.6 0.032 13.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 KZN93635.1 - 0.00041 19.3 0.1 0.00072 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KZN93635.1 - 0.0014 18.4 3.1 0.6 9.8 0.6 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KZN93635.1 - 0.0079 15.1 0.4 0.093 11.6 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KZN93635.1 - 0.0087 16.3 0.0 0.34 11.1 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 KZN93635.1 - 0.048 12.7 1.2 0.087 11.8 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KZN93635.1 - 0.15 12.1 0.0 5.5 7.0 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KZN93635.1 - 0.21 10.0 0.6 2.2 6.6 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.20 KZN93636.1 - 4.4e-28 98.2 0.1 7e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93636.1 - 1.9e-20 73.6 0.1 3.5e-20 72.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93636.1 - 2.3e-11 43.6 0.1 2.3e-11 43.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN93636.1 - 0.00063 19.2 0.1 0.00093 18.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KZN93636.1 - 0.01 15.6 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KZN93636.1 - 0.026 14.3 0.6 0.066 13.0 0.4 1.8 1 1 0 1 1 1 0 ThiF family Polysacc_synt_2 PF02719.10 KZN93636.1 - 0.08 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HHH_5 PF14520.1 KZN93636.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain Amidohydro_1 PF01979.15 KZN93637.1 - 3.7e-37 128.7 0.0 4.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KZN93637.1 - 0.0026 17.5 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KZN93637.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KZN93637.1 - 0.0039 17.2 0.3 2 8.3 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KZN93637.1 - 0.073 12.2 1.4 6.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family Sugar_tr PF00083.19 KZN93638.1 - 2.2e-91 306.7 27.3 2.5e-91 306.5 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93638.1 - 2.4e-30 105.4 51.5 8.4e-26 90.5 19.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN93638.1 - 6.5e-06 24.6 2.2 1.4e-05 23.5 1.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KZN93638.1 - 0.00075 18.0 1.0 0.00075 18.0 0.7 2.9 3 1 0 3 3 3 2 MFS/sugar transport protein TPR_19 PF14559.1 KZN93638.1 - 0.16 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_3 PF05977.8 KZN93638.1 - 0.17 9.9 8.9 0.12 10.4 1.7 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector MtrC PF04211.8 KZN93639.1 - 0.0061 15.6 0.9 0.009 15.0 0.6 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit C DUF1469 PF07332.6 KZN93639.1 - 0.16 11.6 1.9 0.23 11.2 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) ATP1G1_PLM_MAT8 PF02038.11 KZN93639.1 - 0.86 8.6 2.6 1.7 7.7 1.8 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Cu_amine_oxid PF01179.15 KZN93641.1 - 3.1e-169 563.0 0.3 3.7e-169 562.8 0.2 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KZN93641.1 - 9e-09 35.3 0.0 2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KZN93641.1 - 9.4e-07 28.8 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DASH_Spc19 PF08287.6 KZN93642.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Spc19 Isochorismatase PF00857.15 KZN93643.1 - 4.4e-32 111.3 0.0 5.1e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DDE_1 PF03184.14 KZN93644.1 - 5.2e-18 64.9 0.0 7.7e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_1 PF00583.19 KZN93645.1 - 2e-07 30.9 0.1 6.5e-07 29.2 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN93645.1 - 6.7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KZN93645.1 - 0.0002 21.4 0.1 0.0087 16.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KZN93645.1 - 0.00069 19.3 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KZN93645.1 - 0.00089 19.1 0.1 0.0016 18.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN93645.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN93645.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amidohydro_5 PF13594.1 KZN93646.1 - 0.00056 19.6 0.0 1.6 8.6 0.0 3.0 1 1 1 2 2 2 2 Amidohydrolase UPF0118 PF01594.11 KZN93646.1 - 0.014 14.4 9.1 0.21 10.5 2.5 4.3 2 1 3 5 5 5 0 Domain of unknown function DUF20 ApoB100_C PF12491.3 KZN93646.1 - 0.13 11.9 0.1 3.1 7.5 0.0 3.5 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal DUF3427 PF11907.3 KZN93646.1 - 0.22 10.4 1.5 5.8 5.7 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3427) Het-C PF07217.6 KZN93646.1 - 0.42 8.7 1.8 1.3 7.1 0.1 2.4 2 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Glutaredoxin2_C PF04399.8 KZN93646.1 - 7.2 6.1 10.0 36 3.9 0.1 5.9 3 2 5 8 8 8 0 Glutaredoxin 2, C terminal domain APH PF01636.18 KZN93647.1 - 3.5e-15 56.4 0.0 4.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_I_TF PF04090.7 KZN93647.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Choline_kinase PF01633.15 KZN93647.1 - 0.028 13.9 0.0 0.045 13.3 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.13 KZN93648.1 - 5.1e-08 32.6 11.1 5.1e-08 32.6 7.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN93648.1 - 1.7e-05 23.8 0.3 5.4e-05 22.1 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2360 PF10152.4 KZN93648.1 - 1.7 8.8 6.2 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Dickkopf_N PF04706.7 KZN93648.1 - 3.2 7.9 11.7 6.9 6.9 8.1 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Mak10 PF04112.8 KZN93649.1 - 5.8e-55 185.0 0.0 1e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 KZN93650.1 - 3.6e-23 80.8 1.6 3.6e-23 80.8 1.1 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Cpn60_TCP1 PF00118.19 KZN93652.1 - 1.4e-118 396.5 5.4 1.6e-118 396.4 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KZN93652.1 - 0.11 12.1 1.4 0.57 9.8 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) HAMP PF00672.20 KZN93653.1 - 2.6e-35 120.4 12.9 4.1e-09 36.4 0.2 5.8 5 0 0 5 5 5 5 HAMP domain HATPase_c PF02518.21 KZN93653.1 - 1.1e-30 105.5 0.2 2.8e-30 104.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN93653.1 - 5.5e-29 100.4 0.3 3.5e-27 94.6 0.2 2.9 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 KZN93653.1 - 3.1e-16 59.0 0.5 3.7e-15 55.6 0.2 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Lzipper-MIP1 PF14389.1 KZN93653.1 - 0.0073 16.3 1.7 0.78 9.8 0.6 3.1 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 AAA_13 PF13166.1 KZN93653.1 - 0.024 13.1 7.5 0.43 8.9 0.8 3.1 2 1 1 3 3 3 0 AAA domain NAAA-beta PF15508.1 KZN93653.1 - 0.12 12.7 1.7 22 5.5 0.0 4.9 5 2 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 KZN93653.1 - 0.22 11.3 8.3 10 5.9 0.0 4.8 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) Pex19 PF04614.7 KZN93653.1 - 6.3 6.3 12.2 6.2 6.3 1.1 3.0 4 1 0 4 4 4 0 Pex19 protein family CorA PF01544.13 KZN93654.1 - 3.2e-09 36.2 2.1 3.2e-09 36.2 1.4 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KZN93654.1 - 7.5e-08 31.9 0.0 1.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KZN93654.1 - 0.00011 22.1 0.0 0.00054 19.9 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KZN93654.1 - 0.00055 19.5 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_M9_N PF08453.5 KZN93654.1 - 0.013 14.8 0.2 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Mito_carr PF00153.22 KZN93655.1 - 5.5e-61 202.3 0.7 4.9e-19 67.8 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KZN93656.1 - 3.1e-24 85.2 0.7 6e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KZN93657.1 - 5.4e-30 104.5 4.0 7.2e-30 104.0 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93657.1 - 1.5e-23 83.7 1.2 1.9e-23 83.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93657.1 - 2.7e-11 43.4 2.0 4e-11 42.8 1.4 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 KZN93657.1 - 0.0018 17.3 0.3 0.049 12.7 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ACT PF01842.20 KZN93657.1 - 0.013 15.0 1.0 0.085 12.3 0.7 2.2 1 1 0 1 1 1 0 ACT domain PA PF02225.17 KZN93657.1 - 0.045 13.4 0.7 0.14 11.8 0.4 1.9 2 0 0 2 2 2 0 PA domain Kri1 PF05178.7 KZN93657.1 - 0.052 13.8 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 KRI1-like family Sugar_tr PF00083.19 KZN93658.1 - 1.4e-85 287.5 21.9 1.8e-85 287.2 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93658.1 - 2.5e-26 92.2 30.9 3e-26 91.9 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN93658.1 - 0.001 17.5 2.7 0.001 17.5 1.9 3.6 2 2 2 4 4 4 2 MFS/sugar transport protein ADH_N PF08240.7 KZN93659.1 - 5.8e-31 106.4 0.2 5.8e-31 106.4 0.2 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93659.1 - 3.4e-23 81.6 0.0 6.8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN93659.1 - 3.4e-05 24.7 0.0 8.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KZN93659.1 - 0.021 15.3 0.0 0.07 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KZN93659.1 - 0.025 13.9 0.1 0.056 12.8 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 KZN93659.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KZN93659.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 KZN93661.1 - 5.7e-29 101.1 1.7 6.9e-29 100.9 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93661.1 - 1.3e-24 87.3 0.0 1.6e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93661.1 - 4.4e-15 55.7 0.6 6.4e-15 55.2 0.4 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KZN93661.1 - 0.00089 18.4 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KZN93661.1 - 0.0015 18.9 0.7 0.0045 17.3 0.5 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KZN93661.1 - 0.0016 18.6 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KZN93661.1 - 0.0055 16.7 0.1 0.0083 16.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KZN93661.1 - 0.014 15.1 0.2 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.14 KZN93661.1 - 0.015 14.0 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KZN93661.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2492 PF10678.4 KZN93661.1 - 0.026 14.6 0.1 0.095 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) 3HCDH_N PF02737.13 KZN93661.1 - 0.042 13.5 0.3 0.06 12.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KZN93661.1 - 0.043 12.6 0.5 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 KZN93661.1 - 0.045 13.1 0.2 0.06 12.7 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 KZN93661.1 - 0.064 12.8 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RELT PF12606.3 KZN93661.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PRK PF00485.13 KZN93662.1 - 0.00066 19.2 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KZN93662.1 - 0.036 14.3 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain VanY PF02557.12 KZN93662.1 - 0.089 12.6 0.0 0.88 9.4 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase F-box-like PF12937.2 KZN93663.1 - 8.2e-08 31.8 0.0 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KZN93663.1 - 0.0072 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 TPR repeat F-box PF00646.28 KZN93663.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain MIT PF04212.13 KZN93663.1 - 0.052 13.4 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 KZN93663.1 - 0.15 12.0 0.2 1.1 9.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.16 KZN93664.1 - 4.7e-09 36.0 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN93664.1 - 6.2e-09 36.1 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN93664.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KZN93664.1 - 7.9e-05 21.7 0.1 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KZN93664.1 - 0.0029 17.9 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KZN93664.1 - 0.0029 16.5 0.0 0.019 13.9 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KZN93664.1 - 0.0047 15.6 0.0 0.0089 14.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN93664.1 - 0.067 13.0 0.5 0.3 10.9 0.2 2.1 2 1 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 KZN93664.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CMAS PF02353.15 KZN93665.1 - 3.6e-45 154.1 0.0 4.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KZN93665.1 - 1.5e-15 57.2 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN93665.1 - 3.3e-11 43.5 0.0 6.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN93665.1 - 2.7e-08 34.2 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN93665.1 - 4.8e-06 27.1 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93665.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KZN93665.1 - 0.00047 19.5 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KZN93665.1 - 0.0044 17.0 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN93665.1 - 0.0051 16.4 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KZN93665.1 - 0.0071 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KZN93665.1 - 0.0078 15.7 0.0 0.025 14.0 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KZN93665.1 - 0.035 13.1 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 KZN93665.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RSN1_TM PF13967.1 KZN93665.1 - 0.088 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport FtsJ PF01728.14 KZN93665.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase B3_4 PF03483.12 KZN93667.1 - 8.4e-22 77.4 0.0 1.1e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain Glyco_hydro_32C PF08244.7 KZN93668.1 - 9.9e-18 64.3 0.4 6.7e-17 61.6 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KZN93668.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain OB_NTP_bind PF07717.11 KZN93669.1 - 5.2e-20 71.3 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KZN93669.1 - 3.2e-17 62.4 0.2 3.2e-17 62.4 0.2 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KZN93669.1 - 1.3e-12 47.3 0.0 1.4e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN93669.1 - 4.9e-05 22.8 0.0 0.00016 21.2 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN93669.1 - 0.0007 19.7 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KZN93669.1 - 0.0032 16.9 0.0 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KZN93669.1 - 0.0087 15.4 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KZN93669.1 - 0.017 14.0 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KZN93669.1 - 0.088 11.9 0.0 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 KaiC Fungal_trans PF04082.13 KZN93671.1 - 9.2e-09 34.5 4.3 4.7e-08 32.2 0.5 2.6 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93671.1 - 1.9e-08 34.0 10.3 3.5e-08 33.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN93672.1 - 2.6e-43 148.1 43.9 2.6e-43 148.1 30.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KZN93672.1 - 3.1e-07 28.9 18.4 4.2e-07 28.5 12.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RnfC_N PF13375.1 KZN93672.1 - 0.072 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain FAD_binding_3 PF01494.14 KZN93673.1 - 5.9e-14 51.8 0.4 3.3e-13 49.4 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KZN93673.1 - 9e-11 41.2 6.6 1.7e-05 23.9 0.0 3.4 1 1 2 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN93673.1 - 0.00021 20.2 0.8 0.00032 19.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KZN93673.1 - 0.0028 16.1 0.2 0.13 10.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KZN93673.1 - 0.0061 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KZN93673.1 - 0.018 14.1 0.5 0.057 12.4 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KZN93673.1 - 0.025 14.6 0.3 0.14 12.1 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN93673.1 - 0.04 13.7 0.3 0.076 12.8 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93673.1 - 0.058 12.4 0.1 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KZN93673.1 - 0.066 12.0 0.4 0.28 10.0 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN93673.1 - 0.069 11.7 0.6 6.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KZN93673.1 - 0.13 11.1 1.1 0.18 10.6 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 KZN93674.1 - 1.4e-15 57.5 0.1 2.4e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93674.1 - 5.4e-10 39.4 0.1 6.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN93674.1 - 4.7e-08 32.7 0.1 1.7e-07 30.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN93674.1 - 7.2e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN93674.1 - 0.013 15.5 0.1 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN93674.1 - 0.066 12.1 0.2 0.54 9.0 0.1 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 KZN93675.1 - 7.5e-30 103.8 0.0 1.1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KZN93676.1 - 1.8e-23 83.2 0.4 2.6e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93676.1 - 2.6e-14 53.5 0.2 3.6e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93676.1 - 1.1e-11 44.7 0.1 1.5e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KZN93676.1 - 2.2e-09 36.6 0.1 2.8e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KZN93676.1 - 7.5e-08 32.0 0.5 3e-07 30.1 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KZN93676.1 - 0.0017 18.1 1.0 0.003 17.3 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KZN93676.1 - 0.0049 15.7 0.1 0.0073 15.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KZN93676.1 - 0.0085 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tran_WecB PF03808.8 KZN93676.1 - 0.06 12.7 0.1 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.1 KZN93676.1 - 0.076 13.0 0.3 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 NADH(P)-binding HATPase_c PF02518.21 KZN93676.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4243 PF14027.1 KZN93677.1 - 6.1e-94 315.1 0.4 7.4e-94 314.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 KZN93678.1 - 2.4e-16 60.2 0.0 3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KZN93678.1 - 8.3e-07 28.5 0.1 2e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 KZN93678.1 - 0.0009 18.0 0.1 0.0015 17.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN93678.1 - 0.0049 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KZN93678.1 - 0.034 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KZN93678.1 - 0.076 11.9 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein HSP20 PF00011.16 KZN93679.1 - 3.8e-13 49.1 0.2 5.3e-13 48.7 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Scytalone_dh PF02982.9 KZN93680.1 - 2.8e-72 241.5 1.1 3.1e-72 241.3 0.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KZN93680.1 - 4.2e-07 29.9 0.7 6e-07 29.4 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain ketoacyl-synt PF00109.21 KZN93681.1 - 2e-70 237.1 0.1 4.3e-70 236.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KZN93681.1 - 1.6e-48 165.6 0.0 2.6e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KZN93681.1 - 6.7e-32 109.8 1.5 1.6e-31 108.6 1.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KZN93681.1 - 4.3e-10 39.2 0.0 8.8e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KZN93681.1 - 3.3e-09 36.8 0.2 9.4e-09 35.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KZN93681.1 - 0.00017 20.7 0.1 0.00042 19.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_transf_28 PF03033.15 KZN93683.1 - 1.2e-14 54.3 0.1 7.9e-14 51.5 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KZN93683.1 - 1.9e-06 26.6 0.0 3.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KZN93683.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.3 KZN93684.1 - 1.5e-33 114.3 4.8 1.5e-33 114.3 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Cellulase PF00150.13 KZN93685.1 - 8.5e-09 35.0 2.0 6.5e-08 32.1 0.9 2.5 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pyr_redox_3 PF13738.1 KZN93686.1 - 7.2e-24 84.9 0.0 1.3e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN93686.1 - 2.5e-10 39.2 0.0 1.1e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN93686.1 - 5.6e-09 35.9 0.5 4.8e-07 29.7 0.0 3.2 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN93686.1 - 8.2e-08 31.5 0.0 5.8e-06 25.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KZN93686.1 - 7e-06 26.1 0.0 0.0011 19.1 0.0 2.9 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KZN93686.1 - 2.7e-05 24.0 0.4 0.014 15.2 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.19 KZN93686.1 - 0.00051 20.3 0.0 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KZN93686.1 - 0.00066 19.6 0.0 0.064 13.1 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93686.1 - 0.0019 17.3 0.0 0.094 11.7 0.0 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KZN93686.1 - 0.0042 16.0 0.0 0.036 12.9 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KZN93686.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KZN93686.1 - 0.023 13.6 0.1 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KZN93686.1 - 0.064 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Dyp_perox PF04261.7 KZN93687.1 - 2.1e-92 309.2 0.0 2.4e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family adh_short PF00106.20 KZN93688.1 - 1.5e-29 103.0 2.5 2.4e-29 102.3 1.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93688.1 - 1.3e-23 84.0 0.1 1.6e-23 83.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93688.1 - 1.4e-14 54.2 3.2 7.3e-14 51.8 2.2 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KZN93688.1 - 5.1e-08 32.1 0.3 1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KZN93688.1 - 0.00039 19.9 0.9 0.0011 18.4 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KZN93688.1 - 0.032 14.0 0.1 0.077 12.8 0.1 1.8 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KZN93688.1 - 0.07 11.8 0.1 0.089 11.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KZN93689.1 - 1.2e-54 185.4 1.2 1.5e-54 185.1 0.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KZN93690.1 - 3.1e-28 98.7 1.5 4.4e-28 98.2 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93690.1 - 5.8e-27 95.0 0.1 6.8e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93690.1 - 6.7e-11 42.1 0.6 1.1e-10 41.5 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KZN93690.1 - 0.00038 20.1 0.1 0.00077 19.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KZN93690.1 - 0.018 14.6 0.5 0.11 12.0 0.3 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ank_2 PF12796.2 KZN93691.1 - 4.4e-22 78.2 0.0 3.2e-10 40.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN93691.1 - 4.9e-19 67.9 0.4 2.1e-09 37.2 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN93691.1 - 1.2e-18 67.1 0.2 1.3e-07 31.9 0.0 4.2 4 1 0 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KZN93691.1 - 2.6e-18 64.8 2.6 2e-09 36.8 0.1 4.1 4 0 0 4 4 3 3 Ankyrin repeat Ank_3 PF13606.1 KZN93691.1 - 1.1e-14 53.0 4.5 9.3e-07 28.5 0.1 4.7 5 0 0 5 5 4 3 Ankyrin repeat NACHT PF05729.7 KZN93691.1 - 1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KZN93691.1 - 6.7e-07 29.5 0.5 9.8e-05 22.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN93691.1 - 5.1e-06 26.6 0.5 2.5e-05 24.3 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 KZN93691.1 - 0.00096 18.2 0.1 0.076 11.9 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 KZN93691.1 - 0.0048 16.6 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 KZN93691.1 - 0.0059 16.0 0.1 0.037 13.4 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain Clat_adaptor_s PF01217.15 KZN93692.1 - 7.1e-11 41.9 0.0 2.1e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF948 PF06103.6 KZN93693.1 - 0.49 10.2 4.8 0.077 12.8 0.6 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KZN93693.1 - 3.5 7.3 17.8 0.95 9.2 8.3 2.4 2 0 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 KZN93693.1 - 5.4 7.1 15.6 0.36 10.9 4.5 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KZN93693.1 - 8 4.7 15.5 6.9 4.9 9.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4613 PF15390.1 KZN93693.1 - 8.5 4.4 15.4 14 3.7 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PQ-loop PF04193.9 KZN93695.1 - 3.4e-18 64.9 2.1 3.4e-18 64.9 1.5 2.5 4 0 0 4 4 4 1 PQ loop repeat CYSTM PF12734.2 KZN93695.1 - 0.0048 16.9 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 KZN93695.1 - 0.14 12.2 0.2 9.8 6.2 0.1 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L16 PF00252.13 KZN93696.1 - 1.8e-32 111.8 0.1 2.3e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CFEM PF05730.6 KZN93697.1 - 5.4e-05 22.9 1.1 6.4e-05 22.6 0.7 1.1 1 0 0 1 1 1 1 CFEM domain EGF PF00008.22 KZN93697.1 - 0.015 15.2 0.6 0.026 14.4 0.1 1.6 2 0 0 2 2 2 0 EGF-like domain DUF3441 PF11923.3 KZN93698.1 - 4.7e-39 132.4 0.1 4.7e-39 132.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KZN93698.1 - 4.6e-34 117.7 15.5 4.6e-34 117.7 10.7 2.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KZN93698.1 - 1.4e-15 56.9 0.0 3.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Sua5_yciO_yrdC PF01300.13 KZN93699.1 - 1.5e-56 190.4 0.0 2.3e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KZN93699.1 - 1.3e-26 93.0 0.0 2.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.17 KZN93700.1 - 8.1e-75 251.7 0.0 9.2e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KZN93700.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase 2Fe-2S_thioredx PF01257.14 KZN93702.1 - 4.8e-60 201.3 0.1 6.1e-60 201.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.18 KZN93703.1 - 2.2e-22 79.2 0.1 6.2e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KZN93703.1 - 1.9e-13 50.2 0.0 5.5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 KZN93703.1 - 0.0019 18.0 0.0 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HypA PF01155.14 KZN93703.1 - 0.091 12.4 3.2 0.32 10.6 2.2 1.9 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family CSTF2_hinge PF14327.1 KZN93704.1 - 7.8e-29 99.5 2.8 7.8e-29 99.5 1.9 2.6 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KZN93704.1 - 1.6e-19 69.2 0.0 2.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN93704.1 - 7.1e-17 61.1 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KZN93704.1 - 7.2e-17 60.4 8.3 7.2e-17 60.4 5.8 3.0 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KZN93704.1 - 2.1e-07 30.6 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 KZN93704.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Limkain-b1 PF11608.3 KZN93704.1 - 0.084 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 Band_7 PF01145.20 KZN93705.1 - 6.5e-25 88.0 2.2 8.3e-25 87.7 1.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 KZN93706.1 - 4.1e-07 30.2 0.0 2.5e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Sporozoite_P67 PF05642.6 KZN93706.1 - 0.025 12.4 0.1 0.036 11.9 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_4 PF13637.1 KZN93706.1 - 0.049 14.1 0.0 4.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 KZN93706.1 - 0.11 12.3 0.0 0.37 10.6 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat DUF221 PF02714.10 KZN93707.1 - 2.7e-110 368.2 27.3 2.7e-110 368.2 18.9 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KZN93707.1 - 6.9e-47 158.9 0.5 6.9e-47 158.9 0.4 3.2 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KZN93707.1 - 3.2e-14 52.5 0.0 8.6e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KZN93707.1 - 1.8e-11 44.3 6.1 7.8e-05 23.1 0.2 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) GP41 PF00517.12 KZN93707.1 - 0.012 15.1 0.4 0.77 9.2 0.2 2.8 2 1 0 2 2 2 0 Retroviral envelope protein PT-TG PF14449.1 KZN93707.1 - 0.64 9.8 3.7 0.77 9.5 0.2 2.7 3 0 0 3 3 3 0 Pre-toxin TG DUF1682 PF07946.9 KZN93707.1 - 0.7 8.6 3.8 0.23 10.2 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) MCM PF00493.18 KZN93708.1 - 3.7e-139 463.1 0.0 5e-139 462.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KZN93708.1 - 1.9e-20 73.5 0.0 9.5e-20 71.3 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN93708.1 - 6.1e-06 25.5 0.0 0.00018 20.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KZN93708.1 - 1.4e-05 24.7 0.0 3.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KZN93708.1 - 0.0028 17.2 0.0 0.0086 15.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KZN93708.1 - 0.13 11.7 0.1 7.7 5.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_32 PF13654.1 KZN93708.1 - 0.26 9.8 2.2 0.19 10.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain VTC PF09359.5 KZN93709.1 - 3.2e-102 341.3 0.3 6e-102 340.4 0.2 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KZN93709.1 - 8.4e-26 91.3 10.3 1.8e-23 83.7 7.2 2.9 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 KZN93709.1 - 9.4e-11 41.7 5.4 9.4e-11 41.7 3.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Oxidored_q6 PF01058.17 KZN93711.1 - 6.8e-23 80.7 0.0 7.9e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.8 KZN93711.1 - 0.11 12.6 0.4 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region DEAD PF00270.24 KZN93712.1 - 1.6e-17 63.5 0.0 4.1e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN93712.1 - 7.4e-09 35.3 0.0 1.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN93712.1 - 9.5e-06 25.5 0.0 2.3e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 KZN93712.1 - 0.00093 19.3 0.0 0.0044 17.1 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.1 KZN93712.1 - 0.01 15.9 0.1 0.069 13.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF4332 PF14229.1 KZN93712.1 - 0.024 14.6 0.1 0.076 12.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Sigma70_r4 PF04545.11 KZN93712.1 - 0.061 12.6 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 zf-HC5HC2H_2 PF13832.1 KZN93713.1 - 6.1e-22 77.6 0.3 6.1e-22 77.6 0.2 4.3 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KZN93713.1 - 9.1e-22 77.0 1.0 9.1e-22 77.0 0.7 4.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 KZN93713.1 - 6.7e-14 51.6 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KZN93713.1 - 7.6e-10 38.3 51.4 3.9e-07 29.6 5.0 5.1 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 KZN93713.1 - 4.1e-09 35.6 4.0 4.1e-09 35.6 2.8 5.1 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.26 KZN93713.1 - 7.5e-06 25.9 0.0 3.2e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain ADH_zinc_N PF00107.21 KZN93714.1 - 3.9e-25 87.8 0.1 6.3e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN93714.1 - 8.5e-15 55.7 0.0 2.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN93714.1 - 4.3e-10 39.3 0.0 1.3e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain PDEase_I PF00233.14 KZN93715.1 - 1.4e-48 165.7 0.0 2.3e-47 161.7 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Exo70 PF03081.10 KZN93715.1 - 0.18 10.5 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Rdx PF10262.4 KZN93716.1 - 2.9e-30 104.0 0.0 4.2e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 KZN93717.1 - 5.8e-25 86.8 0.0 6.7e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 KZN93717.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like PCI PF01399.22 KZN93718.1 - 3.2e-09 37.0 0.0 3.2e-09 37.0 0.0 3.0 3 0 0 3 3 3 1 PCI domain Acetyltransf_1 PF00583.19 KZN93720.1 - 1.2e-11 44.4 0.1 1.7e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KZN93720.1 - 1.8e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KZN93720.1 - 0.0022 18.1 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KZN93720.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN93720.1 - 0.016 15.0 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN93720.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 KZN93721.1 - 3.7e-21 75.2 49.9 2.1e-14 52.9 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.17 KZN93722.1 - 4.8e-24 83.8 0.2 8.3e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 KOW PF00467.24 KZN93722.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 KOW motif zf-C2H2 PF00096.21 KZN93723.1 - 7.9e-31 104.5 56.3 2.3e-05 24.4 1.6 11.0 11 0 0 11 11 11 10 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN93723.1 - 1.3e-23 82.0 55.0 1.2e-06 28.4 0.2 10.7 12 0 0 12 12 12 7 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN93723.1 - 2.2e-22 77.6 52.4 0.012 15.9 0.2 10.3 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KZN93723.1 - 2.5e-08 33.8 17.2 0.89 9.7 1.4 8.3 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KZN93723.1 - 3.7e-06 26.9 12.3 1 9.6 0.5 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type GAGA PF09237.6 KZN93723.1 - 0.0048 16.4 8.4 0.011 15.3 0.9 3.6 3 0 0 3 3 3 1 GAGA factor zf-H2C2_5 PF13909.1 KZN93723.1 - 0.009 16.1 0.0 0.009 16.1 0.0 10.0 11 0 0 11 11 11 1 C2H2-type zinc-finger domain Ribosomal_L37e PF01907.14 KZN93723.1 - 0.3 10.9 4.9 0.12 12.1 0.4 2.7 2 0 0 2 2 2 0 Ribosomal protein L37e PH PF00169.24 KZN93725.1 - 0.0078 16.3 0.0 0.057 13.6 0.0 2.3 2 0 0 2 2 2 1 PH domain ADH_N PF08240.7 KZN93726.1 - 9.6e-08 31.7 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93726.1 - 0.093 12.2 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KZN93727.1 - 0.00023 20.1 0.3 0.00033 19.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 KZN93728.1 - 7.1e-85 284.7 37.3 1.6e-44 152.4 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KZN93728.1 - 1.4e-67 226.2 0.0 2.4e-32 112.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 KZN93728.1 - 6.3e-13 49.1 0.2 4.1e-07 30.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KZN93728.1 - 5.2e-11 43.0 2.6 0.00071 19.6 0.1 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KZN93728.1 - 2.1e-10 40.2 11.0 0.00077 18.7 0.0 5.1 4 2 0 6 6 6 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KZN93728.1 - 1.7e-08 33.8 0.4 0.00012 21.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KZN93728.1 - 3.1e-08 32.6 0.1 0.0031 16.1 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KZN93728.1 - 1.4e-07 30.8 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KZN93728.1 - 2.8e-07 30.7 2.5 0.053 13.6 0.1 4.0 2 2 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 KZN93728.1 - 1.1e-06 28.2 0.1 0.038 13.5 0.0 3.5 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KZN93728.1 - 1.2e-06 29.3 0.9 0.06 14.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 KZN93728.1 - 1.8e-05 24.4 0.1 1.1 9.0 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KZN93728.1 - 2.1e-05 23.9 2.0 0.25 10.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 KZN93728.1 - 4.3e-05 23.1 1.2 3.5 7.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KZN93728.1 - 8e-05 23.0 4.0 0.062 13.6 0.2 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KZN93728.1 - 0.00017 21.5 0.0 0.41 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KZN93728.1 - 0.00037 20.3 1.6 0.6 10.0 0.0 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KZN93728.1 - 0.00069 19.3 0.0 2.4 7.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KZN93728.1 - 0.0008 19.6 1.5 2.4 8.3 0.3 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KZN93728.1 - 0.001 18.9 0.0 1.4 8.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 KZN93728.1 - 0.0013 18.7 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN93728.1 - 0.0026 18.0 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KZN93728.1 - 0.0069 16.1 0.0 1.5 8.5 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_15 PF13175.1 KZN93728.1 - 0.013 14.6 0.0 0.097 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Synapsin_N PF10581.4 KZN93728.1 - 0.015 15.0 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Synapsin N-terminal Mg_chelatase PF01078.16 KZN93728.1 - 0.02 14.0 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KZN93728.1 - 0.021 14.2 0.6 0.52 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain NB-ARC PF00931.17 KZN93728.1 - 0.022 13.6 0.9 1.3 7.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.7 KZN93728.1 - 0.023 13.7 0.1 3.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 KZN93728.1 - 0.03 13.7 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KZN93728.1 - 0.038 13.9 0.2 19 5.2 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KZN93728.1 - 0.051 13.1 0.2 4.3 6.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KZN93728.1 - 0.061 13.4 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KZN93728.1 - 0.065 12.8 0.6 13 5.3 0.0 2.9 3 0 0 3 3 2 0 NACHT domain G-alpha PF00503.15 KZN93728.1 - 0.069 11.8 0.1 7.9 5.0 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit PRK PF00485.13 KZN93728.1 - 0.14 11.7 0.2 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sugar_tr PF00083.19 KZN93729.1 - 3.4e-85 286.2 30.3 4e-85 286.0 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93729.1 - 1.8e-19 69.7 49.2 8.7e-14 50.9 12.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Neurensin PF14927.1 KZN93729.1 - 0.017 14.5 1.9 0.082 12.2 0.0 2.9 3 0 0 3 3 3 0 Neurensin MFS_2 PF13347.1 KZN93729.1 - 3.1 6.0 36.0 0.066 11.6 3.0 3.4 2 2 2 4 4 4 0 MFS/sugar transport protein ADH_N PF08240.7 KZN93730.1 - 4.6e-34 116.4 0.1 7.8e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93730.1 - 5.1e-25 87.5 0.3 7.5e-25 86.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN93730.1 - 0.00045 21.1 0.0 0.00075 20.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KZN93730.1 - 0.0011 19.5 0.0 0.0032 18.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 KZN93730.1 - 0.0012 18.4 0.2 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KZN93730.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KZN93730.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 KZN93730.1 - 0.089 13.2 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KZN93730.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FGGY_C PF02782.11 KZN93731.1 - 9.3e-48 162.4 0.1 1.5e-47 161.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KZN93731.1 - 7.3e-24 84.4 0.0 8.9e-22 77.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KZN93731.1 - 0.062 12.5 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MtrB PF05440.7 KZN93732.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B GST_C PF00043.20 KZN93733.1 - 2.1e-15 56.4 0.0 3.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KZN93733.1 - 1.3e-14 54.1 0.0 2.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KZN93733.1 - 8.7e-14 51.4 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KZN93733.1 - 1.9e-09 37.4 0.0 4.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KZN93733.1 - 8.6e-07 29.3 0.2 1.2e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KZN93733.1 - 2.9e-06 27.0 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KZN93734.1 - 3.1e-29 101.7 31.2 1.5e-28 99.5 19.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN93734.1 - 0.0021 16.3 1.8 0.0021 16.3 1.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2534 PF10749.4 KZN93734.1 - 3.7 7.5 7.9 0.48 10.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) COPIIcoated_ERV PF07970.7 KZN93735.1 - 2.6e-69 233.2 0.0 5.7e-66 222.3 0.0 2.6 2 1 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KZN93735.1 - 8.5e-35 118.6 0.0 1.7e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 KZN93736.1 - 3.3e-11 42.4 0.3 5.9e-11 41.6 0.2 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 KZN93736.1 - 5.8e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 KZN93736.1 - 1.5e-07 30.8 4.3 0.00015 21.2 0.1 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN93736.1 - 9e-05 22.1 0.1 0.00027 20.6 0.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KZN93736.1 - 0.016 15.1 0.1 12 6.4 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat DEC-1_N PF04625.8 KZN93736.1 - 0.63 8.6 7.0 1.1 7.8 4.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Vps53_N PF04100.7 KZN93737.1 - 3.6e-108 361.7 2.5 3.6e-108 361.7 1.7 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 KZN93737.1 - 3e-06 26.3 6.5 7.3e-06 25.0 4.5 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RINT1_TIP1 PF04437.8 KZN93737.1 - 2.7e-05 22.9 0.7 2.7e-05 22.9 0.5 2.8 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Spc7 PF08317.6 KZN93737.1 - 0.004 15.8 5.5 0.0072 15.0 3.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein COG2 PF06148.6 KZN93737.1 - 0.0047 16.7 3.2 0.0047 16.7 2.2 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.4 KZN93737.1 - 0.018 14.8 0.7 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DUF1515 PF07439.6 KZN93737.1 - 0.66 9.8 3.1 0.9 9.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Fungal_trans PF04082.13 KZN93739.1 - 5e-21 74.7 0.2 1e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93739.1 - 7.9e-10 38.4 10.9 1.6e-09 37.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_2 PF13337.1 KZN93739.1 - 0.21 9.8 0.0 0.37 9.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease Ribosomal_L10 PF00466.15 KZN93740.1 - 3.5e-24 84.6 0.0 6.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KZN93740.1 - 3.8e-20 72.0 3.7 3.8e-20 72.0 2.6 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 KZN93741.1 - 1.8e-06 27.6 0.5 0.00013 21.7 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 KZN93741.1 - 0.031 13.3 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region URO-D PF01208.12 KZN93742.1 - 3.5e-123 410.9 0.0 3.9e-123 410.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 KZN93742.1 - 0.076 12.6 0.2 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Phloem filament protein PP1 dCMP_cyt_deam_1 PF00383.17 KZN93743.1 - 2.6e-23 81.5 0.0 3.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KZN93743.1 - 8.3e-06 25.6 2.2 0.077 12.8 0.5 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 KZN93743.1 - 0.0054 16.4 0.0 0.0095 15.6 0.0 1.4 1 1 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 KZN93743.1 - 0.058 12.9 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain CTDII PF01556.13 KZN93744.1 - 6.4e-21 74.0 0.3 5.6e-18 64.6 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KZN93744.1 - 2.5e-20 71.9 3.7 9.4e-20 70.1 2.6 2.0 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KZN93744.1 - 6.2e-13 48.5 19.3 1.1e-12 47.7 13.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KZN93744.1 - 0.1 12.2 9.5 0.079 12.6 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 KZN93744.1 - 7.3 6.4 5.3 5 6.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) NMO PF03060.10 KZN93745.1 - 6.6e-44 150.3 1.1 1.3e-29 103.4 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KZN93745.1 - 3e-09 36.2 0.0 0.0011 17.9 0.0 2.9 2 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KZN93745.1 - 5.3e-08 32.0 2.0 7.3e-08 31.6 0.8 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KZN93745.1 - 0.00048 19.1 0.0 0.00078 18.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KZN93745.1 - 0.098 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Aldedh PF00171.17 KZN93746.1 - 3e-108 362.1 4.0 5.7e-104 348.0 1.3 3.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KZN93746.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) NmrA PF05368.8 KZN93747.1 - 2.1e-17 63.1 0.0 2.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN93747.1 - 3.6e-13 49.9 0.1 1e-12 48.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KZN93747.1 - 4.3e-08 32.8 0.1 7.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN93747.1 - 2.8e-05 22.9 0.1 4.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KZN93747.1 - 0.00083 18.4 0.2 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KZN93747.1 - 0.079 13.0 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_1 PF00175.16 KZN93748.1 - 2.4e-15 57.0 0.0 4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN93748.1 - 4.7e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 KZN93748.1 - 3.1e-07 30.7 0.0 3.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Globin NAD_binding_6 PF08030.7 KZN93748.1 - 2.4e-06 27.5 0.0 0.0012 18.8 0.1 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Protoglobin PF11563.3 KZN93748.1 - 0.031 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Protoglobin FAD_binding_8 PF08022.7 KZN93748.1 - 0.12 12.2 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 FAD-binding domain Sulfate_transp PF00916.15 KZN93749.1 - 4e-76 255.6 8.6 7e-76 254.8 6.0 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KZN93749.1 - 1.4e-31 107.9 5.0 1.4e-31 107.9 3.5 3.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KZN93749.1 - 3.1e-07 29.8 0.0 5.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 KZN93749.1 - 2.2 8.0 10.5 0.031 13.9 1.2 2.5 2 0 0 2 2 2 0 Stannin transmembrane MFS_1 PF07690.11 KZN93750.1 - 2.5e-26 92.2 68.2 3.8e-13 48.8 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pantoate_transf PF02548.10 KZN93751.1 - 3.2e-104 347.6 0.5 3.8e-104 347.4 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KZN93751.1 - 3.3e-08 33.0 0.6 1.1e-07 31.3 0.4 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Amidohydro_2 PF04909.9 KZN93751.1 - 0.13 11.8 0.3 0.31 10.5 0.2 1.8 1 1 0 1 1 1 0 Amidohydrolase NanE PF04131.9 KZN93751.1 - 0.33 9.8 2.4 15 4.5 0.0 2.7 2 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Rab5ip PF07019.7 KZN93752.1 - 1.2e-06 28.5 2.8 1.2e-06 28.5 1.9 2.1 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) SAM_2 PF07647.12 KZN93753.1 - 1.9e-09 37.2 0.1 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KZN93753.1 - 2.3e-05 24.4 0.6 4.6e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 KZN93753.1 - 0.18 10.1 3.7 0.54 8.5 1.7 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 TPR_11 PF13414.1 KZN93754.1 - 2.4e-25 87.9 16.5 2.1e-05 24.1 0.1 8.8 7 2 1 9 9 9 5 TPR repeat TPR_19 PF14559.1 KZN93754.1 - 7.2e-21 74.3 11.5 4e-06 27.0 0.0 8.3 6 2 2 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 KZN93754.1 - 3.3e-18 65.5 9.3 9.9e-05 22.4 0.6 7.2 7 1 1 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KZN93754.1 - 2e-14 52.5 3.7 0.025 14.7 0.0 7.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KZN93754.1 - 1.1e-13 51.3 15.2 5.3e-05 23.7 0.0 7.1 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KZN93754.1 - 5.2e-13 47.7 7.0 0.31 10.9 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93754.1 - 9.4e-13 47.5 21.1 0.00029 21.2 0.4 10.0 7 3 4 11 11 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KZN93754.1 - 6e-12 45.3 19.4 0.00021 21.1 0.6 7.0 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KZN93754.1 - 2.5e-11 42.4 7.1 0.21 11.4 0.0 8.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN93754.1 - 3.2e-11 42.2 26.2 0.22 11.5 0.2 10.1 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 KZN93754.1 - 2e-08 33.5 21.8 0.6 9.8 0.0 10.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_15 PF13429.1 KZN93754.1 - 2.7e-05 23.3 2.2 2.3 7.1 0.0 4.9 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KZN93754.1 - 7.6e-05 22.4 8.3 9.1e-05 22.2 0.3 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KZN93754.1 - 0.0011 19.2 11.4 2 9.0 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KZN93754.1 - 0.0027 16.4 0.1 2 7.0 0.0 2.4 2 0 0 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit Alkyl_sulf_dimr PF14863.1 KZN93754.1 - 0.0062 16.7 0.6 1.1 9.4 0.0 3.2 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_20 PF14561.1 KZN93754.1 - 0.007 16.4 4.4 9.9 6.3 0.0 5.2 4 2 2 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 KZN93754.1 - 0.013 14.2 5.8 2.4 6.8 0.1 3.9 3 2 1 4 4 4 0 NMDA receptor-regulated protein 1 SNAP PF14938.1 KZN93754.1 - 0.014 14.5 2.0 1.1 8.3 0.1 2.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP BTAD PF03704.12 KZN93754.1 - 0.018 15.3 2.7 0.067 13.4 0.5 2.8 2 1 0 3 3 2 0 Bacterial transcriptional activator domain PPR PF01535.15 KZN93754.1 - 0.84 9.7 4.2 3.7 7.7 0.2 3.8 5 0 0 5 5 3 0 PPR repeat YL1 PF05764.8 KZN93754.1 - 6.8 6.2 11.0 2.2 7.8 4.5 2.0 2 0 0 2 2 2 0 YL1 nuclear protein TPR_4 PF07721.9 KZN93754.1 - 8.4 7.1 11.8 23 5.7 0.1 6.1 7 0 0 7 7 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 KZN93755.1 - 2.2e-28 99.0 43.1 2.4e-24 85.7 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Haem_oxygenas_2 PF14518.1 KZN93756.1 - 5.5e-13 48.9 0.1 1.2e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Iron-containing redox enzyme DIOX_N PF14226.1 KZN93757.1 - 3.5e-08 33.9 0.0 6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN93757.1 - 1.1e-07 32.0 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KZN93758.1 - 5.1e-68 229.3 0.0 6.6e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 KZN93758.1 - 1.6e-21 77.5 0.0 4.8e-21 76.0 0.0 1.8 1 1 1 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KZN93758.1 - 1.1e-07 31.9 0.0 4.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 KZN93758.1 - 5.5e-07 29.7 0.1 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 KZN93758.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family SPR1 PF15356.1 KZN93758.1 - 0.11 12.8 0.1 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 GOLGA2L5 PF15070.1 KZN93758.1 - 0.42 9.0 0.0 0.63 8.4 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 p450 PF00067.17 KZN93759.1 - 2.1e-34 118.8 0.0 2.7e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KZN93760.1 - 3.7e-33 114.7 0.1 1.1e-32 113.1 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KZN93760.1 - 5e-05 23.0 0.0 0.00017 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN93760.1 - 0.016 15.5 0.0 1.8 8.9 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 KZN93761.1 - 1.8e-34 119.0 0.0 2.6e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KZN93761.1 - 1.7e-05 24.5 0.1 4.1e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain FAD_binding_3 PF01494.14 KZN93762.1 - 5.2e-17 61.9 0.0 9.4e-08 31.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN93762.1 - 4.3e-10 39.0 0.2 0.00029 19.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN93762.1 - 0.00014 21.8 0.0 0.0004 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KZN93762.1 - 0.00014 21.8 0.0 0.0015 18.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KZN93762.1 - 0.00026 19.8 0.0 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.22 KZN93762.1 - 0.00039 20.7 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN93762.1 - 0.0013 17.7 0.0 0.003 16.5 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 KZN93762.1 - 0.0017 17.2 0.0 0.0081 15.0 0.0 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KZN93762.1 - 0.0039 15.8 0.1 0.01 14.5 0.0 1.6 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 KZN93762.1 - 0.0057 15.5 0.1 0.046 12.5 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN93762.1 - 0.0072 16.4 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN93762.1 - 0.03 12.7 0.1 0.088 11.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KZN93762.1 - 0.093 12.4 0.5 0.54 10.0 0.4 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KZN93762.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KZN93762.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP_mutase PF13714.1 KZN93763.1 - 1.9e-64 217.1 2.9 2.1e-64 216.9 2.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Cellulase-like PF12876.2 KZN93763.1 - 0.023 15.1 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF3336 PF11815.3 KZN93764.1 - 1.6e-49 167.1 3.7 2.6e-49 166.4 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KZN93764.1 - 3.2e-19 69.6 0.1 9.7e-19 68.1 0.0 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase RHH_4 PF13467.1 KZN93764.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF2790 PF10976.3 KZN93764.1 - 0.092 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) LRR_8 PF13855.1 KZN93765.1 - 1.5e-16 59.8 5.5 7.7e-09 35.1 1.2 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KZN93765.1 - 2.2e-16 59.0 15.0 8e-06 25.3 0.2 5.6 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KZN93765.1 - 9.5e-09 34.1 10.7 0.27 11.4 0.1 6.8 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 KZN93765.1 - 0.018 15.1 18.1 12 6.6 0.1 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 KZN93765.1 - 0.04 13.9 11.9 4.4 7.6 0.1 5.9 6 1 1 7 7 7 0 Leucine Rich repeat Metallophos PF00149.23 KZN93766.1 - 1.4e-44 151.8 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APH PF01636.18 KZN93767.1 - 2.8e-19 69.8 0.1 6.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KZN93767.1 - 0.021 14.1 0.0 4.8 6.4 0.0 2.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KZN93767.1 - 0.046 12.7 0.0 0.67 8.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.16 KZN93768.1 - 5.6e-65 217.8 0.0 6.6e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KZN93768.1 - 4e-10 38.9 0.0 1.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KZN93768.1 - 2.3e-08 33.4 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KZN93768.1 - 3.8e-07 30.6 0.0 5.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KZN93768.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KZN93768.1 - 2.4e-05 23.7 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KZN93768.1 - 0.00014 21.0 0.0 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KZN93768.1 - 0.02 14.3 0.0 0.65 9.4 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KZN93768.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 KZN93769.1 - 1.1e-155 518.8 31.3 1.1e-155 518.8 21.7 3.8 2 2 0 3 3 3 2 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.2 KZN93770.1 - 4.2e-09 36.6 0.0 7.1e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93770.1 - 3.2e-06 26.9 0.0 5.6e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Senescence PF06911.7 KZN93771.1 - 0.0031 17.2 3.6 0.0039 16.9 2.5 1.1 1 0 0 1 1 1 1 Senescence-associated protein THDPS_N_2 PF14805.1 KZN93771.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal IQ PF00612.22 KZN93773.1 - 0.00043 19.6 4.4 0.0021 17.5 0.3 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif Polysacc_deac_1 PF01522.16 KZN93774.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Zn_clus PF00172.13 KZN93775.1 - 1.1e-07 31.6 8.5 2.5e-07 30.4 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 KZN93776.1 - 7.1e-25 87.7 0.1 9.3e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN93776.1 - 0.0001 21.9 0.3 0.00016 21.2 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KZN93776.1 - 0.00053 19.7 0.6 0.0014 18.4 0.4 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Vezatin PF12632.2 KZN93777.1 - 2.3e-62 210.3 0.0 1.1e-61 208.1 0.0 2.0 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.13 KZN93778.1 - 7.2e-55 183.9 2.6 1.5e-54 182.8 1.8 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KZN93778.1 - 6.6e-52 174.7 0.0 1.4e-51 173.7 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KZN93778.1 - 1.9e-08 33.7 0.1 2.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KZN93778.1 - 0.00024 20.1 0.1 0.008 15.1 0.0 2.2 2 0 0 2 2 2 1 Hus1-like protein p450 PF00067.17 KZN93780.1 - 2.9e-46 157.9 0.0 4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hid1 PF12722.2 KZN93781.1 - 0.046 11.4 0.6 0.06 11.0 0.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec61_beta PF03911.11 KZN93782.1 - 4e-19 68.1 0.6 5.2e-19 67.7 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.12 KZN93783.1 - 1e-19 70.4 31.8 1.7e-19 69.8 22.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Zn_clus PF00172.13 KZN93784.1 - 0.42 10.5 0.3 0.42 10.5 0.2 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynein_light PF01221.13 KZN93785.1 - 4.2e-12 45.9 0.8 6.5e-12 45.2 0.6 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 KZN93785.1 - 0.041 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Sigma70_r2 PF04542.9 KZN93785.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 RRM_1 PF00076.17 KZN93786.1 - 3.5e-76 250.8 0.8 9.4e-18 63.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN93786.1 - 8.9e-65 214.6 0.5 1.8e-13 50.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN93786.1 - 7.7e-36 121.7 0.2 4.1e-11 42.5 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KZN93786.1 - 1.5e-07 31.0 0.3 1.5 8.5 0.0 5.4 5 0 0 5 5 5 3 Limkain b1 Nup35_RRM_2 PF14605.1 KZN93786.1 - 6.9e-06 25.7 0.0 2.6 7.8 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KZN93786.1 - 0.0019 18.0 1.9 3 7.7 0.0 4.6 4 1 1 5 5 5 1 RNA binding motif TEA PF01285.13 KZN93787.1 - 1.5e-143 479.0 0.3 2e-143 478.6 0.2 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family Aldo_ket_red PF00248.16 KZN93788.1 - 4.4e-51 173.3 0.0 5.1e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 KZN93789.1 - 4.2e-24 84.3 1.1 5.8e-24 83.8 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CAV_VP3 PF04771.7 KZN93789.1 - 0.098 12.6 0.5 0.16 11.9 0.3 1.4 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein Chordopox_L2 PF05803.7 KZN93790.1 - 2.9 7.5 5.4 7.2 6.3 0.3 2.7 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Abhydrolase_6 PF12697.2 KZN93791.1 - 1.1e-25 90.8 0.2 1.5e-25 90.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN93791.1 - 8.5e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KZN93791.1 - 0.004 16.4 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KZN93791.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase TMEM151 PF14857.1 KZN93791.1 - 0.15 10.6 0.5 0.23 9.9 0.4 1.2 1 0 0 1 1 1 0 TMEM151 family DNAPolymera_Pol PF11590.3 KZN93792.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Glyco_hydro_76 PF03663.9 KZN93793.1 - 2e-132 442.0 18.3 2.5e-132 441.7 12.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 KZN93793.1 - 0.015 15.3 0.4 0.033 14.2 0.1 1.7 2 0 0 2 2 2 0 Cloacin immunity protein Prothymosin PF03247.9 KZN93795.1 - 0.14 12.2 37.5 0.17 12.0 26.0 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family RXT2_N PF08595.6 KZN93795.1 - 0.18 11.5 11.7 0.21 11.3 8.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KZN93795.1 - 0.25 10.9 17.3 0.25 10.9 12.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TraH_2 PF06871.6 KZN93795.1 - 0.26 10.7 5.3 0.29 10.5 3.7 1.0 1 0 0 1 1 1 0 TraH_2 FYDLN_acid PF09538.5 KZN93795.1 - 0.37 11.4 12.6 0.42 11.2 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2796 PF10986.3 KZN93795.1 - 0.4 10.6 8.2 0.4 10.6 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Tim54 PF11711.3 KZN93795.1 - 0.61 8.6 10.6 0.58 8.7 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 WBS_methylT PF12589.3 KZN93795.1 - 0.74 10.3 7.3 0.87 10.1 5.1 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome NOA36 PF06524.7 KZN93795.1 - 0.96 8.6 14.7 1 8.5 10.2 1.0 1 0 0 1 1 1 0 NOA36 protein CKAP2_C PF15297.1 KZN93795.1 - 0.97 8.1 11.7 0.96 8.1 8.1 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 KZN93795.1 - 1.2 7.0 16.4 1.2 7.0 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 KZN93795.1 - 1.5 8.8 14.5 1.5 8.7 10.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 KZN93795.1 - 1.7 8.4 9.0 1.6 8.4 6.2 1.0 1 0 0 1 1 1 0 DDHD domain Nucleoplasmin PF03066.10 KZN93795.1 - 1.7 8.1 27.2 2.4 7.6 18.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Med4 PF10018.4 KZN93795.1 - 1.9 7.8 17.6 2 7.7 12.2 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 YqfQ PF14181.1 KZN93795.1 - 2.4 8.1 14.1 2.5 8.1 9.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein DDRGK PF09756.4 KZN93795.1 - 2.4 7.5 23.4 2.7 7.3 16.2 1.0 1 0 0 1 1 1 0 DDRGK domain Pox_Ag35 PF03286.9 KZN93795.1 - 2.5 7.5 15.6 2.7 7.4 10.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 KZN93795.1 - 2.8 6.8 7.6 2.7 6.9 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.9 KZN93795.1 - 2.9 7.9 11.6 3.3 7.7 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1510 PF07423.6 KZN93795.1 - 2.9 7.2 20.4 2.9 7.1 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HNOBA PF07701.9 KZN93795.1 - 3 6.9 8.8 3.6 6.7 6.1 1.1 1 0 0 1 1 1 0 Heme NO binding associated Daxx PF03344.10 KZN93795.1 - 3.5 5.9 28.4 3.8 5.8 19.7 1.0 1 0 0 1 1 1 0 Daxx Family AIF_C PF14721.1 KZN93795.1 - 3.5 7.8 6.4 3.8 7.7 4.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BUD22 PF09073.5 KZN93795.1 - 3.6 6.5 19.8 4 6.4 13.8 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 KZN93795.1 - 3.9 6.4 16.9 4 6.3 11.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_polI_A34 PF08208.6 KZN93795.1 - 3.9 7.0 15.5 4.3 6.9 10.8 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MIP-T3 PF10243.4 KZN93795.1 - 4.2 5.7 19.1 4.7 5.5 13.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 KZN93795.1 - 4.2 6.7 19.0 4.8 6.5 13.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO GOLD_2 PF13897.1 KZN93795.1 - 5.1 7.3 8.9 5.5 7.2 6.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NPR3 PF03666.8 KZN93795.1 - 5.2 5.4 6.8 5.4 5.4 4.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.10 KZN93795.1 - 5.3 5.5 8.2 5 5.6 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FHIPEP PF00771.15 KZN93795.1 - 5.5 5.1 6.8 5.5 5.1 4.7 1.0 1 0 0 1 1 1 0 FHIPEP family DUF3306 PF11748.3 KZN93795.1 - 5.8 7.6 13.0 6.3 7.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Pox_RNA_Pol_19 PF05320.7 KZN93795.1 - 6.1 6.5 14.4 7.4 6.2 10.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SspB PF04386.8 KZN93795.1 - 6.4 6.3 13.2 6.5 6.3 9.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B SprA-related PF12118.3 KZN93795.1 - 6.9 5.8 12.9 7 5.8 9.0 1.0 1 0 0 1 1 1 0 SprA-related family DUF2457 PF10446.4 KZN93795.1 - 7.5 5.1 23.9 7.3 5.1 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KZN93795.1 - 8.9 4.0 27.8 9.4 4.0 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family Upf2 PF04050.9 KZN93795.1 - 9.1 6.0 23.3 10 5.8 16.2 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Usp PF00582.21 KZN93795.1 - 9.9 6.3 9.8 12 6.1 6.8 1.1 1 0 0 1 1 1 0 Universal stress protein family Amino_oxidase PF01593.19 KZN93796.1 - 7.1e-11 41.8 0.0 2.7e-08 33.3 0.0 2.6 2 1 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN93796.1 - 2.2e-10 40.3 0.1 5e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KZN93796.1 - 3.3e-08 33.0 0.6 6.1e-08 32.1 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KZN93796.1 - 5.4e-08 32.1 0.4 4.5e-06 25.8 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KZN93796.1 - 8.3e-08 31.4 1.3 1.5e-07 30.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KZN93796.1 - 1e-06 28.9 0.0 2.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN93796.1 - 1.3e-06 28.4 0.1 3.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN93796.1 - 4.9e-06 25.2 2.0 7.8e-06 24.6 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KZN93796.1 - 1.7e-05 24.0 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN93796.1 - 2.4e-05 24.6 1.0 0.00014 22.1 0.5 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KZN93796.1 - 6e-05 22.0 0.4 8.3e-05 21.6 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KZN93796.1 - 6.6e-05 22.1 0.6 0.00011 21.3 0.4 1.3 1 0 0 1 1 1 1 Thi4 family IlvN PF07991.7 KZN93796.1 - 0.014 14.7 0.3 0.024 13.9 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 KZN93796.1 - 0.019 14.5 0.2 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 KZN93796.1 - 0.029 13.2 0.1 0.064 12.1 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KZN93796.1 - 0.049 13.8 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 KZN93796.1 - 0.12 10.9 0.6 0.19 10.3 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ABC_tran PF00005.22 KZN93797.1 - 1e-40 139.2 0.4 8.8e-32 110.2 0.1 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KZN93797.1 - 6.8e-30 104.4 39.4 6.4e-20 71.6 11.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KZN93797.1 - 1.5e-12 48.1 0.1 1.1e-05 25.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KZN93797.1 - 4.2e-06 26.9 0.1 0.085 13.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KZN93797.1 - 6.8e-06 26.0 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KZN93797.1 - 1.1e-05 24.8 2.0 0.14 11.6 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KZN93797.1 - 2.5e-05 23.6 1.1 0.0018 17.5 0.1 3.0 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KZN93797.1 - 4e-05 23.1 3.6 0.05 12.9 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 KZN93797.1 - 5.1e-05 24.0 0.1 0.09 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KZN93797.1 - 0.00026 21.3 0.0 0.6 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KZN93797.1 - 0.00034 19.8 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 KZN93797.1 - 0.00053 19.6 0.0 0.058 13.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KZN93797.1 - 0.002 17.7 0.7 0.019 14.6 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KZN93797.1 - 0.0025 17.7 0.2 0.86 9.5 0.0 3.3 3 1 1 4 4 3 1 AAA domain AAA_10 PF12846.2 KZN93797.1 - 0.0036 16.7 0.7 2 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 KZN93797.1 - 0.0037 17.7 0.1 2.1 8.8 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein AAA PF00004.24 KZN93797.1 - 0.0038 17.4 0.0 0.25 11.5 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KZN93797.1 - 0.0047 16.8 0.0 5 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.9 KZN93797.1 - 0.0056 16.4 0.6 1.7 8.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KZN93797.1 - 0.0073 15.1 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 KZN93797.1 - 0.016 15.3 0.1 4 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KZN93797.1 - 0.027 14.4 2.3 1.6 8.6 0.3 2.6 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KZN93797.1 - 0.054 12.3 0.9 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KZN93797.1 - 0.058 12.4 0.2 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 KZN93797.1 - 0.067 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 KZN93797.1 - 0.092 12.4 1.9 10 5.8 0.3 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KZN93797.1 - 0.094 12.5 0.7 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.1 KZN93797.1 - 0.1 12.5 0.1 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 KZN93797.1 - 0.17 10.4 0.2 0.3 9.7 0.1 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein cobW PF02492.14 KZN93797.1 - 0.18 11.2 1.0 6.4 6.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KZN93797.1 - 0.18 11.2 0.9 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KZN93797.1 - 0.22 11.8 3.4 7.8 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KZN93798.1 - 1.9e-20 72.8 38.7 1.4e-17 63.4 13.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN93798.1 - 9e-07 27.8 7.7 9e-07 27.8 5.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KZN93798.1 - 0.065 11.2 4.0 0.02 12.9 0.4 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lactonase PF10282.4 KZN93799.1 - 7.7e-87 291.5 0.0 9.5e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.7 KZN93799.1 - 1.6 8.8 9.5 0.16 12.0 1.3 3.3 3 1 0 3 3 3 0 Putative Ig domain Amidase PF01425.16 KZN93800.1 - 1.6e-11 43.7 0.0 1.8e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Amidase XkdW PF09636.5 KZN93800.1 - 0.13 12.1 1.0 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 XkdW protein Ank_2 PF12796.2 KZN93801.1 - 5.3e-56 186.9 13.7 4.6e-12 46.1 0.4 6.4 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN93801.1 - 4.1e-51 168.3 16.8 7.3e-09 35.0 0.2 11.2 11 0 0 11 11 10 8 Ankyrin repeat Ank_4 PF13637.1 KZN93801.1 - 9e-40 134.3 14.1 1.5e-05 25.3 0.0 10.0 6 2 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KZN93801.1 - 2.4e-37 126.1 20.0 2.8e-08 33.7 0.0 8.7 6 2 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN93801.1 - 2.2e-35 117.1 9.5 2.7e-05 23.9 0.0 10.7 10 0 0 10 10 10 5 Ankyrin repeat AAA_22 PF13401.1 KZN93801.1 - 2.4e-07 30.9 0.3 1.5e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KZN93801.1 - 5.1e-07 29.8 0.0 2.3e-06 27.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KZN93801.1 - 2.3e-06 27.3 0.0 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 KZN93801.1 - 0.00034 20.8 0.0 0.002 18.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ORC2 PF04084.9 KZN93801.1 - 0.0014 17.5 0.3 0.0027 16.5 0.2 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 KAP_NTPase PF07693.9 KZN93801.1 - 0.0032 16.5 0.1 0.18 10.7 0.2 2.2 1 1 1 2 2 2 1 KAP family P-loop domain DUF2075 PF09848.4 KZN93801.1 - 0.0061 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KZN93801.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KZN93801.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KZN93801.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1147 PF06615.6 KZN93802.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) FAD_binding_4 PF01565.18 KZN93803.1 - 1.2e-28 99.2 3.6 1.6e-28 98.9 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KZN93803.1 - 1.7e-05 24.6 0.4 3.4e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Turandot PF07240.6 KZN93803.1 - 0.14 11.7 0.0 0.89 9.0 0.0 2.2 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot AMP-binding PF00501.23 KZN93804.1 - 1.9e-77 260.4 0.0 2.3e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme LRR_4 PF12799.2 KZN93805.1 - 1.4e-38 129.8 33.1 7.2e-10 38.2 0.6 7.7 3 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN93805.1 - 9.7e-24 82.9 58.5 2.6e-08 33.4 1.9 5.5 3 1 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KZN93805.1 - 2.7e-13 47.9 29.2 0.11 12.6 0.4 10.5 10 2 1 11 11 11 5 Leucine Rich Repeat LRR_9 PF14580.1 KZN93805.1 - 7.2e-12 45.2 18.6 5.6e-07 29.2 2.3 3.9 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.1 KZN93805.1 - 1.6e-10 39.9 23.3 0.11 12.6 0.5 10.0 7 3 4 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 KZN93805.1 - 3.9e-10 38.2 17.8 0.43 10.9 0.0 9.5 8 2 1 9 9 9 3 Leucine rich repeat CLU_N PF15044.1 KZN93805.1 - 3.5 7.8 6.2 12 6.0 0.8 3.4 1 1 0 2 2 2 0 Mitochondrial function, CLU-N-term NIF PF03031.13 KZN93806.1 - 5.1e-52 175.7 0.2 1.8e-51 173.9 0.1 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KZN93806.1 - 0.13 12.4 0.1 1.3 9.2 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_membrane_2 PF06472.10 KZN93807.1 - 9.4e-92 307.1 0.2 1.9e-91 306.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KZN93807.1 - 2.4e-11 44.0 0.0 4.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 KZN93807.1 - 0.024 14.9 1.3 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KZN93807.1 - 0.04 13.4 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PgaD PF13994.1 KZN93807.1 - 0.081 12.4 1.1 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 PgaD-like protein RuvB_N PF05496.7 KZN93807.1 - 0.2 10.6 0.0 0.5 9.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Clr2 PF10383.4 KZN93808.1 - 2.3e-24 86.0 0.0 3.8e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Grp1_Fun34_YaaH PF01184.14 KZN93809.1 - 1.2e-82 276.2 11.3 1.4e-82 276.0 7.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 2OG-FeII_Oxy PF03171.15 KZN93810.1 - 0.0094 16.2 0.0 0.029 14.6 0.0 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_2 PF00152.15 KZN93811.1 - 2.7e-75 253.2 0.0 3.3e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KZN93811.1 - 1.3e-10 40.9 0.1 3.1e-10 39.7 0.1 1.7 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KZN93811.1 - 6.6e-07 28.7 0.0 0.00078 18.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.1 KZN93811.1 - 0.0029 17.4 0.0 0.13 12.1 0.0 2.0 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KZN93811.1 - 0.053 13.0 0.0 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 KZN93812.1 - 1.1e-25 88.7 0.7 1.3e-25 88.4 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KZN93812.1 - 0.029 13.8 0.7 0.035 13.5 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2796 PF10986.3 KZN93814.1 - 0.83 9.6 11.3 0.78 9.6 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Frag1 PF10277.4 KZN93815.1 - 3.1e-32 111.8 17.6 3.5e-32 111.6 12.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 KZN93815.1 - 0.0071 15.0 18.6 0.012 14.3 12.9 1.3 1 1 0 1 1 1 1 Voltage-dependent anion channel CLTH PF10607.4 KZN93816.1 - 1.2e-28 99.6 0.0 2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KZN93816.1 - 8.8e-18 63.7 0.5 2.6e-17 62.2 0.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KZN93816.1 - 2.6e-05 23.5 0.0 5.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KZN93816.1 - 0.00031 20.4 0.2 0.00058 19.6 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KZN93816.1 - 0.00044 19.9 0.2 0.00073 19.2 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Syntaxin PF00804.20 KZN93816.1 - 0.0016 18.5 0.8 0.0067 16.5 0.1 2.1 2 0 0 2 2 2 1 Syntaxin zf-C3HC4_2 PF13923.1 KZN93816.1 - 0.0056 16.6 0.5 0.011 15.7 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KZN93816.1 - 0.0067 16.0 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KZN93816.1 - 0.0095 15.5 0.3 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LURAP PF14854.1 KZN93816.1 - 0.04 13.6 1.6 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Leucine rich adaptor protein zf-C3HC4_4 PF15227.1 KZN93816.1 - 0.077 12.8 0.6 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING BTB PF00651.26 KZN93817.1 - 0.00028 20.8 0.0 0.0012 18.8 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.22 KZN93818.1 - 3.7e-09 36.8 0.0 7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain Peptidase_M76 PF09768.4 KZN93818.1 - 0.19 11.2 0.0 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase M76 family Ribosomal_L18ae PF01775.12 KZN93819.1 - 5.3e-59 197.5 0.3 6.4e-59 197.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 KZN93820.1 - 3.5e-32 111.2 0.0 5.3e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KZN93820.1 - 3e-21 75.3 0.0 8.6e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KZN93820.1 - 7.6e-09 35.6 0.0 3.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.14 KZN93821.1 - 5e-11 42.6 1.5 1e-10 41.7 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KZN93821.1 - 5.2e-07 29.9 3.1 1.5e-06 28.4 1.7 2.1 2 0 0 2 2 2 1 HMG-box domain Amidohydro_1 PF01979.15 KZN93822.1 - 2.8e-62 211.3 2.3 5e-62 210.4 1.2 1.8 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 KZN93822.1 - 1.7e-55 186.3 1.0 3.3e-55 185.3 0.3 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KZN93822.1 - 6.2e-40 135.0 0.1 2.8e-39 132.9 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KZN93822.1 - 2.7e-37 126.7 0.5 6.3e-37 125.5 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KZN93822.1 - 2.3e-07 30.5 4.1 6.3e-07 29.1 2.9 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KZN93822.1 - 1.1e-05 24.8 4.2 0.00036 19.8 0.1 3.0 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KZN93822.1 - 0.02 14.9 0.5 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Amidohydrolase Hpt PF01627.18 KZN93823.1 - 0.023 14.6 0.3 0.052 13.5 0.1 1.6 2 0 0 2 2 2 0 Hpt domain Lactamase_B_2 PF12706.2 KZN93826.1 - 1.6e-11 44.0 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KZN93826.1 - 3.3e-07 30.3 0.0 1.1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 KZN93826.1 - 0.00029 20.5 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CamS PF07537.6 KZN93827.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor DUF1656 PF07869.7 KZN93827.1 - 0.22 11.3 0.9 0.4 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) NPR2 PF06218.6 KZN93828.1 - 1.1e-130 436.1 0.0 2.1e-130 435.2 0.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Ada3 PF10198.4 KZN93829.1 - 3.4e-40 136.8 0.1 1.1e-39 135.1 0.1 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Ribosomal_L15e PF00827.12 KZN93831.1 - 7.3e-89 296.3 14.1 8.4e-89 296.1 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Pox_P4B PF03292.9 KZN93831.1 - 0.08 10.8 0.1 0.11 10.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein HECT PF00632.20 KZN93832.1 - 4.4e-74 249.4 0.0 6.3e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 KZN93832.1 - 0.084 12.6 0.3 0.19 11.4 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DAO PF01266.19 KZN93833.1 - 3e-53 181.0 1.7 3.7e-53 180.7 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN93833.1 - 3.3e-06 27.0 0.1 1.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KZN93833.1 - 1.4e-05 25.3 0.1 0.00012 22.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KZN93833.1 - 0.00014 21.1 1.9 0.0015 17.6 1.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KZN93833.1 - 0.00015 20.9 0.3 0.021 13.9 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 KZN93833.1 - 0.0063 16.8 0.1 0.29 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KZN93833.1 - 0.015 14.3 0.6 0.049 12.7 0.0 2.0 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.19 KZN93833.1 - 0.015 14.1 0.5 0.35 9.6 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KZN93833.1 - 0.024 14.5 0.1 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KZN93833.1 - 0.024 13.1 0.1 0.37 9.2 0.0 2.3 2 1 1 3 3 3 0 HI0933-like protein adh_short PF00106.20 KZN93833.1 - 0.063 13.1 1.6 0.15 11.9 0.3 2.2 3 0 0 3 3 3 0 short chain dehydrogenase NAD_binding_9 PF13454.1 KZN93833.1 - 0.11 12.2 0.2 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 KZN93835.1 - 4.8e-13 48.5 3.0 1.3e-12 47.1 0.1 2.3 1 1 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.13 KZN93836.1 - 1.4e-22 79.8 0.0 2.8e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.15 KZN93837.1 - 6.8e-89 298.2 0.0 8e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.13 KZN93840.1 - 3.6e-24 85.0 0.3 3.6e-24 85.0 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain RRM_1 PF00076.17 KZN93841.1 - 4.7e-80 263.2 6.6 8.4e-21 73.3 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN93841.1 - 1.5e-50 169.0 0.9 1.6e-12 47.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN93841.1 - 1.5e-38 130.4 0.6 3.1e-08 33.3 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KZN93841.1 - 2.3e-31 107.2 2.3 6.1e-31 105.9 0.7 2.5 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KZN93841.1 - 1.6e-06 27.7 0.2 2.6 7.8 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KZN93841.1 - 1.7e-05 24.9 0.1 0.59 10.4 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 KZN93841.1 - 0.0019 17.9 5.5 1 9.1 0.3 3.7 3 0 0 3 3 3 1 Limkain b1 CSD PF00313.17 KZN93841.1 - 0.043 13.5 3.1 26 4.6 0.0 3.6 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KZN93841.1 - 0.058 12.9 3.0 6.3 6.3 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SOBP PF15279.1 KZN93841.1 - 6 7.1 11.6 5.6 7.2 7.0 1.6 1 1 0 1 1 1 0 Sine oculis-binding protein HECT PF00632.20 KZN93842.1 - 1.2e-82 277.6 0.0 2.8e-82 276.4 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KZN93842.1 - 0.074 12.7 0.6 0.25 11.0 0.4 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif MRP-L27 PF09809.4 KZN93843.1 - 0.024 14.2 2.3 0.078 12.5 0.8 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L27 Ribosomal_L14e PF01929.12 KZN93843.1 - 0.041 14.2 0.0 0.099 13.0 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L14 Utp14 PF04615.8 KZN93844.1 - 3.8e-221 736.2 78.6 3.8e-221 736.2 54.5 2.1 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro_81 PF03639.8 KZN93845.1 - 1.2e-197 658.1 6.0 1.5e-197 657.8 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Dynamin_M PF01031.15 KZN93845.1 - 0.29 9.8 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region Metallophos_2 PF12850.2 KZN93846.1 - 2e-11 43.9 0.0 5.6e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KZN93846.1 - 4.1e-10 39.3 0.5 5.9e-09 35.5 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S8e PF01201.17 KZN93847.1 - 3.8e-47 159.7 1.1 4.4e-47 159.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e TFIIF_alpha PF05793.7 KZN93848.1 - 0.99 7.7 18.3 1.3 7.2 12.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 KZN93848.1 - 3.2 8.1 26.1 1.1 9.5 6.1 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2812 PF11193.3 KZN93848.1 - 3.8 7.6 7.1 5.8 7.1 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) TFIIF_alpha PF05793.7 KZN93849.1 - 0.73 8.1 13.2 1.1 7.5 9.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 KZN93849.1 - 7.3 5.8 35.8 8.3 5.6 24.8 1.1 1 0 0 1 1 1 0 Vta1 like SPX PF03105.14 KZN93850.1 - 5.6e-50 170.6 0.0 1.3e-49 169.4 0.0 1.7 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KZN93850.1 - 1.9e-31 109.4 39.9 2.6e-31 109.0 27.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Ribosomal_S7 PF00177.16 KZN93850.1 - 2.9e-23 82.0 0.0 6.3e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CitMHS PF03600.11 KZN93850.1 - 5.6e-14 51.4 44.8 5.6e-13 48.1 16.4 2.1 1 1 1 2 2 2 2 Citrate transporter MEDS PF14417.1 KZN93850.1 - 0.0065 15.5 0.3 0.047 12.7 0.1 2.1 2 0 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Na_Ca_ex PF01699.19 KZN93851.1 - 1.6e-44 150.8 28.1 8.5e-23 80.5 7.8 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DOCK-C2 PF14429.1 KZN93852.1 - 2.2e-35 121.9 0.0 4.7e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KZN93852.1 - 2.3e-13 49.8 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KZN93852.1 - 1.4e-05 24.3 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KZN93852.1 - 9.6e-05 21.8 0.0 0.00075 19.0 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KZN93852.1 - 0.043 13.2 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Ribosomal_S19 PF00203.16 KZN93852.1 - 0.063 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S19 MeMO_Hyd_G PF02964.11 KZN93852.1 - 0.19 11.6 0.3 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain Pox_F16 PF04708.7 KZN93852.1 - 0.19 10.9 0.0 0.46 9.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus F16 protein CD47 PF04549.9 KZN93852.1 - 0.51 10.3 0.1 0.99 9.3 0.0 1.3 1 0 0 1 1 1 0 CD47 transmembrane region Sec3_C PF09763.4 KZN93853.1 - 9.9e-223 741.2 0.0 1.6e-222 740.5 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KZN93853.1 - 5.6e-31 106.2 0.0 1.1e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KZN93853.1 - 0.0019 18.3 0.2 0.0063 16.6 0.1 1.9 1 0 0 1 1 1 1 Sec3 exocyst complex subunit SRP40_C PF05022.7 KZN93854.1 - 1.5e-21 76.6 0.1 4.1e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 KZN93854.1 - 9.1 4.2 53.8 13 3.8 37.3 1.1 1 0 0 1 1 1 0 Utp14 protein F-box-like PF12937.2 KZN93855.1 - 5.7e-06 25.9 0.1 2.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN93855.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF805 PF05656.9 KZN93855.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) p450 PF00067.17 KZN93856.1 - 3.1e-56 190.8 0.0 4e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TENA_THI-4 PF03070.11 KZN93856.1 - 0.045 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF1992 PF09350.5 KZN93858.1 - 8.2e-25 86.4 0.3 2.3e-24 85.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) SNARE_assoc PF09335.6 KZN93859.1 - 0.0052 16.9 4.1 0.0083 16.3 2.8 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein CcmD PF04995.9 KZN93860.1 - 0.11 12.2 1.2 2.6 7.8 0.8 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) 7tm_1 PF00001.16 KZN93860.1 - 0.16 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2459 PF09601.5 KZN93861.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) Tub_2 PF04525.7 KZN93862.1 - 8e-08 31.8 0.1 1.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Tubby C 2 Glyco_hydro_108 PF05838.7 KZN93863.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase 108 ApoL PF05461.6 KZN93863.1 - 0.15 11.2 0.3 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein L MBOAT_2 PF13813.1 KZN93864.1 - 1.2e-17 63.6 3.6 5.4e-17 61.6 2.5 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family P5CR_dimer PF14748.1 KZN93865.1 - 6.5e-20 71.1 0.5 8.1e-19 67.6 0.1 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KZN93865.1 - 3.6e-16 59.3 0.1 8e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KZN93865.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KZN93865.1 - 0.098 12.4 0.3 0.22 11.3 0.2 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.10 KZN93866.1 - 1.9e-15 56.4 0.0 3.7e-13 48.9 0.0 3.4 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KZN93866.1 - 1e-07 32.1 0.0 3.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Acetyltransf_8 PF13523.1 KZN93867.1 - 3.9e-49 166.4 0.0 5.7e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KZN93867.1 - 0.038 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ECH PF00378.15 KZN93868.1 - 7e-43 146.5 0.0 9e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Cyclin_N PF00134.18 KZN93869.1 - 7.8e-12 44.8 0.1 1.1e-10 41.1 0.0 2.5 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.6 KZN93869.1 - 1.7e-09 38.2 0.0 3.4e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Prp19_bind PF06991.6 KZN93869.1 - 0.036 13.3 0.8 0.054 12.7 0.5 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Glyco_hydro_12 PF01670.11 KZN93870.1 - 1.3e-37 128.9 1.1 2.3e-37 128.1 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF336 PF03928.9 KZN93870.1 - 0.078 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF336) ERG2_Sigma1R PF04622.7 KZN93871.1 - 1.2e-95 318.8 0.6 1.4e-95 318.6 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3687 PF12459.3 KZN93871.1 - 0.018 14.2 0.2 0.053 12.7 0.2 1.8 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein VWA_3 PF13768.1 KZN93872.1 - 2.7e-28 98.5 0.0 5.1e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KZN93872.1 - 5.6e-15 55.0 0.1 1.2e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.1 KZN93872.1 - 1e-14 53.6 0.0 2.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KZN93872.1 - 1e-10 42.0 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KZN93872.1 - 3.3e-09 36.7 0.0 7.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KZN93872.1 - 0.00025 20.2 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KZN93872.1 - 0.0034 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus PTPS PF01242.14 KZN93872.1 - 0.022 14.4 0.0 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Amidohydro_2 PF04909.9 KZN93873.1 - 3.7e-32 111.9 0.0 4.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KZN93873.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 TatD related DNase ApbA PF02558.11 KZN93874.1 - 5.9e-29 100.4 0.0 8e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KZN93874.1 - 4.3e-25 88.1 0.0 7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ThiF PF00899.16 KZN93874.1 - 0.015 15.1 0.6 0.035 13.9 0.3 1.7 2 0 0 2 2 2 0 ThiF family Retrotrans_gag PF03732.12 KZN93875.1 - 0.092 12.8 0.4 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein MFS_1 PF07690.11 KZN93876.1 - 5.8e-32 110.7 25.6 5.8e-32 110.7 17.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 KZN93877.1 - 7.2e-18 64.6 0.0 2.8e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93877.1 - 9.2e-08 31.4 1.0 0.0064 15.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KZN93877.1 - 0.031 14.0 0.1 0.076 12.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN93877.1 - 0.17 10.8 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like adh_short PF00106.20 KZN93879.1 - 4.7e-27 94.9 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN93879.1 - 1.7e-10 41.1 0.0 3.8e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN93879.1 - 3e-10 40.0 0.1 6.5e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KZN93879.1 - 2.1e-05 24.0 0.1 3.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN93879.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN93879.1 - 0.0025 16.5 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KZN93879.1 - 0.0033 17.4 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 KZN93879.1 - 0.0091 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.1 KZN93879.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 KZN93879.1 - 0.053 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 KZN93879.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fungal_trans_2 PF11951.3 KZN93880.1 - 9.2e-09 34.3 0.4 2.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93880.1 - 0.00025 20.8 12.0 0.00047 19.9 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.7 KZN93882.1 - 1.6e-28 99.3 0.0 2.2e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KZN93882.1 - 1.2e-08 34.7 0.0 1.7e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN93882.1 - 4.6e-05 22.2 0.0 0.041 12.5 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KZN93882.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KZN93882.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KZN93882.1 - 0.0064 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF3318 PF11780.3 KZN93882.1 - 0.026 14.0 0.0 0.067 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Pkinase PF00069.20 KZN93883.1 - 7.1e-31 107.2 0.0 1e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN93883.1 - 7.8e-11 41.5 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KZN93883.1 - 0.00017 21.4 0.0 0.00066 19.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN93883.1 - 0.0055 16.2 0.1 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KZN93883.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KZN93883.1 - 0.045 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KZN93883.1 - 0.27 9.9 0.0 0.4 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CMAS PF02353.15 KZN93884.1 - 0.08 12.0 0.2 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ATP_bind_3 PF01171.15 KZN93885.1 - 4e-19 68.7 0.0 6.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KZN93885.1 - 0.0014 18.0 3.5 0.0014 18.0 2.4 2.4 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 KZN93885.1 - 0.019 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KZN93885.1 - 0.044 12.3 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.15 KZN93885.1 - 2.7 7.7 10.9 1.6 8.5 0.6 2.6 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Complex1_LYR_2 PF13233.1 KZN93886.1 - 2.7e-20 72.7 0.1 3.1e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like RasGEF PF00617.14 KZN93887.1 - 6.7e-46 156.3 1.5 1.1e-45 155.7 1.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KZN93887.1 - 6.2e-14 51.9 0.0 1.9e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KZN93887.1 - 4.4e-07 30.3 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Neisseria_TspB PF05616.8 KZN93888.1 - 4.2 5.6 6.6 6.6 4.9 4.6 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Nfu_N PF08712.6 KZN93889.1 - 1.2e-30 104.9 0.0 4.6e-29 99.8 0.0 2.5 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KZN93889.1 - 1.1e-22 79.5 0.2 2.2e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain RdRP_1 PF00680.15 KZN93889.1 - 0.12 10.5 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Sugar_tr PF00083.19 KZN93890.1 - 5.4e-73 246.1 25.4 6.1e-73 245.9 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93890.1 - 7e-14 51.2 33.3 3.2e-09 35.9 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.3 KZN93890.1 - 0.29 11.2 3.8 8.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) PSP1 PF04468.7 KZN93891.1 - 1.6e-30 104.9 1.3 2.5e-30 104.3 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FRG1 PF06229.7 KZN93892.1 - 8.8e-59 198.1 0.3 1.3e-58 197.6 0.2 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KZN93892.1 - 0.078 13.0 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.7 KZN93893.1 - 2.7e-35 120.4 2.0 5.2e-35 119.4 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN93893.1 - 4.1e-16 58.7 0.0 6.6e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KZN93893.1 - 0.00085 18.4 0.6 0.0014 17.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KZN93893.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DUF2318 PF10080.4 KZN93893.1 - 0.0089 15.7 0.8 7.2 6.4 0.1 3.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2318) Gp_dh_N PF00044.19 KZN93893.1 - 0.012 15.5 0.1 0.08 12.8 0.1 2.1 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KZN93893.1 - 0.019 14.9 0.1 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KZN93893.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.11 KZN93893.1 - 0.035 14.4 0.0 0.089 13.1 0.0 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KZN93893.1 - 0.049 13.7 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.1 KZN93893.1 - 0.072 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.22 KZN93893.1 - 0.087 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vps52 PF04129.7 KZN93894.1 - 5.3e-120 401.3 0.0 6.8e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KZN93894.1 - 6.9e-08 31.1 0.0 1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF2552 PF10827.3 KZN93894.1 - 0.041 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) ATG16 PF08614.6 KZN93894.1 - 0.043 13.6 2.4 0.086 12.6 1.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Sec8_exocyst PF04048.9 KZN93894.1 - 0.074 12.6 0.2 0.074 12.6 0.2 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain eIF-5a PF01287.15 KZN93895.1 - 9.7e-28 95.9 2.0 1.5e-27 95.3 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KZN93895.1 - 0.00069 19.2 0.2 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KZN93895.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Nitro_FeMo-Co PF02579.12 KZN93895.1 - 0.044 13.8 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor RRN7 PF11781.3 KZN93896.1 - 4.1e-08 32.5 4.5 4.1e-08 32.5 3.1 1.7 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 Yip1 PF04893.12 KZN93897.1 - 6.5e-16 58.3 14.5 9.8e-16 57.7 10.1 1.3 1 1 0 1 1 1 1 Yip1 domain CopD PF05425.8 KZN93897.1 - 0.00055 20.1 4.3 0.087 13.0 0.2 2.3 2 0 0 2 2 2 2 Copper resistance protein D RabGAP-TBC PF00566.13 KZN93898.1 - 1.4e-24 86.7 0.0 2.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 KZN93899.1 - 8.9e-133 443.0 0.0 4.7e-132 440.6 0.0 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KZN93899.1 - 7.3e-07 28.5 0.0 2.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 CPSF A subunit region PQQ_3 PF13570.1 KZN93899.1 - 0.0062 16.7 0.6 3.6 7.9 0.1 4.0 4 0 0 4 4 4 1 PQQ-like domain Katanin_con80 PF13925.1 KZN93899.1 - 0.029 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 con80 domain of Katanin PQQ_2 PF13360.1 KZN93899.1 - 0.061 12.7 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 PQQ-like domain GTP_EFTU PF00009.22 KZN93900.1 - 5.7e-32 110.6 0.0 5.7e-32 110.6 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KZN93900.1 - 9.2e-18 64.1 0.1 2.4e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KZN93900.1 - 2.2e-12 46.9 0.6 6.3e-10 39.0 0.0 3.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KZN93900.1 - 1.7e-06 27.9 0.1 8.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KZN93900.1 - 0.00035 20.2 0.0 0.00093 18.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 KZN93900.1 - 0.011 16.1 0.0 0.011 16.1 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein GTP_EFTU_D4 PF14578.1 KZN93900.1 - 0.015 14.9 0.1 0.058 13.0 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu domain 4 AAA_22 PF13401.1 KZN93900.1 - 0.048 13.8 0.0 0.22 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain Rhodanese PF00581.15 KZN93901.1 - 2.5e-11 43.9 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 KZN93902.1 - 3.8e-54 183.9 0.0 5e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPR_3 PF13812.1 KZN93904.1 - 4.4e-24 82.6 7.8 0.0025 17.9 0.0 11.4 11 0 0 11 11 11 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 KZN93904.1 - 3.8e-22 77.9 3.5 5e-08 32.7 0.0 8.1 7 2 2 9 9 9 3 PPR repeat family PPR PF01535.15 KZN93904.1 - 6.6e-18 63.3 3.6 0.0072 16.2 0.0 9.6 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.2 KZN93904.1 - 1.7e-07 30.5 0.0 0.81 9.2 0.0 5.5 5 0 0 5 5 5 3 PPR repeat Glyco_trans_4_2 PF13477.1 KZN93904.1 - 0.2 11.4 0.0 0.61 9.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like TPR_12 PF13424.1 KZN93904.1 - 0.28 11.1 1.6 5.5 7.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MCM PF00493.18 KZN93905.1 - 1.1e-128 428.7 0.1 1.5e-128 428.2 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KZN93905.1 - 7.9e-15 55.4 0.0 1.8e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KZN93905.1 - 3.6e-06 26.2 0.0 4.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KZN93905.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.7 KZN93905.1 - 2.7 6.2 12.7 3.9 5.7 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spo7 PF03907.8 KZN93906.1 - 1.9e-65 220.4 0.0 2.4e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Pex14_N PF04695.8 KZN93906.1 - 1.2 9.1 7.8 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 KZN93907.1 - 8.7e-24 84.6 3.2 8.7e-24 84.6 2.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN93907.1 - 3.4e-16 59.5 0.1 1.5e-15 57.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN93907.1 - 1.4e-11 44.3 0.1 2.7e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 KZN93907.1 - 5e-05 22.5 0.0 8.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KZN93907.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 KZN93907.1 - 0.0042 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KZN93907.1 - 0.0059 16.2 0.1 0.055 13.0 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KZN93907.1 - 0.013 14.9 0.0 0.22 10.9 0.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KZN93907.1 - 0.051 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 KZN93907.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.15 KZN93907.1 - 0.16 12.1 2.8 0.34 11.1 0.3 2.6 2 1 0 2 2 2 0 Thioesterase domain TatD_DNase PF01026.16 KZN93908.1 - 4.7e-36 124.2 0.0 8.6e-36 123.4 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase RXT2_N PF08595.6 KZN93908.1 - 0.071 12.9 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Fungal_trans PF04082.13 KZN93909.1 - 3.2e-23 81.9 0.0 5.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93909.1 - 4e-09 36.2 11.9 5.9e-09 35.6 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.17 KZN93910.1 - 6.8e-21 75.0 0.1 1.7e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Prefoldin_2 PF01920.15 KZN93911.1 - 5.9e-25 87.0 7.2 6.9e-25 86.8 5.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KZN93911.1 - 0.0032 17.1 5.9 0.41 10.3 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit GAS PF13851.1 KZN93911.1 - 0.005 16.0 8.9 0.0085 15.3 6.2 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding STAT_alpha PF01017.15 KZN93911.1 - 0.0081 15.8 7.0 0.01 15.5 4.9 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain DASH_Dad3 PF08656.5 KZN93911.1 - 0.012 15.2 4.0 0.015 14.9 0.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2205 PF10224.4 KZN93911.1 - 0.016 14.7 1.3 0.016 14.7 0.9 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Tho2 PF11262.3 KZN93911.1 - 0.037 13.0 4.0 0.66 8.9 0.0 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Baculo_PEP_C PF04513.7 KZN93911.1 - 0.059 13.1 0.4 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 KZN93911.1 - 0.06 13.2 9.1 0.06 13.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3371 PF11851.3 KZN93911.1 - 0.07 13.8 1.4 0.12 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) PEP-utilisers_N PF05524.8 KZN93911.1 - 0.071 12.9 0.6 0.1 12.4 0.4 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TroA PF01297.12 KZN93911.1 - 0.081 12.1 2.1 0.2 10.8 0.4 1.9 2 0 0 2 2 2 0 Periplasmic solute binding protein family FliE PF02049.13 KZN93911.1 - 0.099 12.6 4.6 0.31 11.0 1.1 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE FTA4 PF13093.1 KZN93911.1 - 0.11 11.8 3.8 0.17 11.3 2.4 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ATP-synt_D PF01813.12 KZN93911.1 - 0.15 11.6 1.9 4.7 6.7 0.1 2.1 2 0 0 2 2 2 0 ATP synthase subunit D WXG100 PF06013.7 KZN93911.1 - 0.16 11.9 2.3 1.3 9.0 0.6 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 KZN93911.1 - 0.23 11.8 4.4 0.28 11.6 0.8 2.0 1 1 0 2 2 2 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KZN93911.1 - 0.25 9.1 2.3 0.37 8.5 1.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M75 PF09375.5 KZN93911.1 - 0.25 10.6 5.0 2.5 7.3 1.3 2.0 2 0 0 2 2 2 0 Imelysin CENP-F_leu_zip PF10473.4 KZN93911.1 - 0.49 10.2 6.3 0.59 9.9 0.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cytochrom_B562 PF07361.6 KZN93911.1 - 0.65 10.4 6.1 0.46 10.9 1.5 2.0 2 0 0 2 2 2 0 Cytochrome b562 IncA PF04156.9 KZN93911.1 - 0.87 9.1 8.5 2.3 7.7 5.9 1.6 1 1 0 1 1 1 0 IncA protein Muted PF14942.1 KZN93911.1 - 0.89 9.4 5.6 3 7.7 1.0 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein AAA_32 PF13654.1 KZN93911.1 - 0.92 8.0 6.3 1.8 7.1 4.4 1.5 1 1 0 1 1 1 0 AAA domain DASH_Dad2 PF08654.5 KZN93911.1 - 1.3 9.0 5.4 1.4 8.9 0.4 2.5 2 1 1 3 3 3 0 DASH complex subunit Dad2 Fib_alpha PF08702.5 KZN93911.1 - 1.5 8.8 7.2 56 3.8 0.3 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF607 PF04678.8 KZN93911.1 - 1.6 8.5 4.5 1.8 8.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Seryl_tRNA_N PF02403.17 KZN93911.1 - 2.3 8.2 6.9 1.7 8.6 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 KZN93911.1 - 2.3 8.5 7.0 6.2 7.1 1.6 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 KZN93911.1 - 2.7 7.8 10.6 0.14 11.9 2.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EAP30 PF04157.11 KZN93911.1 - 3.1 6.9 6.3 0.79 8.8 1.1 2.0 1 1 0 2 2 2 0 EAP30/Vps36 family GrpE PF01025.14 KZN93911.1 - 3.5 7.1 7.9 15 5.0 5.5 1.8 1 1 0 1 1 1 0 GrpE DUF972 PF06156.8 KZN93911.1 - 3.6 7.9 5.9 71 3.8 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 KZN93911.1 - 3.8 5.8 7.6 0.63 8.3 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 KZN93911.1 - 4.5 7.2 6.8 2.3 8.2 1.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor OmpH PF03938.9 KZN93911.1 - 5.4 6.9 9.2 2.1 8.2 2.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nop25 PF09805.4 KZN93911.1 - 5.6 7.0 7.1 1.9 8.5 1.6 1.9 1 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spc24 PF08286.6 KZN93911.1 - 6.1 6.5 10.8 0.89 9.2 2.6 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HA2 PF04408.18 KZN93912.1 - 7.5e-24 83.7 0.0 2.8e-23 81.8 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KZN93912.1 - 1.1e-22 79.9 0.0 9.7e-22 76.9 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KZN93912.1 - 3.1e-14 52.5 0.0 1e-13 50.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KZN93912.1 - 1.5e-09 37.5 0.2 1.8e-07 30.8 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KZN93912.1 - 5.5e-05 23.3 0.1 0.00022 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KZN93912.1 - 0.00069 19.4 0.0 0.29 10.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KZN93912.1 - 0.0014 17.6 0.1 0.0039 16.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 KZN93912.1 - 0.0023 17.8 0.1 0.023 14.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 KZN93912.1 - 0.0065 15.9 0.4 0.025 14.0 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KZN93912.1 - 0.0089 15.7 0.1 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 KZN93912.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KZN93912.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KZN93912.1 - 0.013 15.1 1.1 0.4 10.3 0.0 3.0 3 0 0 3 3 3 0 NACHT domain KaiC PF06745.8 KZN93912.1 - 0.034 13.2 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KZN93912.1 - 0.04 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KZN93912.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KZN93912.1 - 0.058 13.7 0.0 0.38 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KZN93912.1 - 0.062 12.9 0.6 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 KZN93912.1 - 0.086 12.4 0.0 0.086 12.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KZN93912.1 - 0.11 13.0 0.0 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein DAD PF02109.11 KZN93915.1 - 5.4e-42 142.3 0.6 3.8e-41 139.6 0.4 1.9 1 1 0 1 1 1 1 DAD family Fungal_trans PF04082.13 KZN93916.1 - 1.6e-21 76.3 0.1 3e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93916.1 - 4.2e-08 32.9 12.4 4.2e-08 32.9 8.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KZN93917.1 - 1.6e-69 234.6 14.7 3.6e-69 233.4 10.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN93917.1 - 5.8e-23 81.1 20.9 9.3e-23 80.4 10.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF86 PF01934.12 KZN93918.1 - 0.053 13.1 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF86 Glyco_hydro_43 PF04616.9 KZN93919.1 - 1.4e-67 227.7 1.4 1.8e-67 227.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_3 PF00933.16 KZN93920.1 - 1.1e-78 264.2 0.0 2e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KZN93920.1 - 1.4e-56 191.5 0.0 6.4e-56 189.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KZN93920.1 - 1.3e-23 82.7 0.1 2.5e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KZN93920.1 - 2.5e-09 36.9 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.13 KZN93921.1 - 2.4e-08 33.7 12.4 4.4e-08 32.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1768 PF08719.6 KZN93922.1 - 1.3e-48 164.6 0.4 1.9e-48 164.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Abhydrolase_6 PF12697.2 KZN93923.1 - 2.5e-38 132.2 0.0 2.9e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN93923.1 - 1.2e-33 116.6 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN93923.1 - 3.8e-24 85.1 0.1 1.9e-15 56.8 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KZN93923.1 - 1e-13 50.9 1.2 2.6e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KZN93923.1 - 3.8e-08 32.7 0.2 0.0017 17.6 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.5 KZN93923.1 - 0.00017 20.5 0.2 0.00045 19.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 KZN93923.1 - 0.00019 20.9 0.0 0.00056 19.4 0.0 1.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 KZN93923.1 - 0.00034 19.9 0.0 0.05 12.8 0.0 2.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KZN93923.1 - 0.0022 17.4 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.8 KZN93923.1 - 0.0037 16.8 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase DUF915 PF06028.6 KZN93923.1 - 0.0096 15.0 0.1 0.023 13.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 KZN93923.1 - 0.014 13.6 0.1 0.91 7.7 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II UPF0227 PF05728.7 KZN93923.1 - 0.076 12.7 0.0 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) AXE1 PF05448.7 KZN93923.1 - 0.11 11.0 0.1 0.19 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 KZN93923.1 - 0.12 11.1 0.1 0.3 9.8 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Pyr_redox_3 PF13738.1 KZN93924.1 - 0.00018 21.6 0.0 0.00044 20.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.1 KZN93925.1 - 0.0027 17.8 0.0 0.019 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KZN93925.1 - 0.011 15.1 0.0 0.04 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KZN93925.1 - 0.043 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KZN93925.1 - 0.055 13.4 0.8 0.32 10.9 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 KZN93925.1 - 0.079 12.8 0.0 0.58 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.11 KZN93926.1 - 1.5e-32 112.7 46.0 1.9e-21 76.2 10.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KZN93926.1 - 0.66 9.7 9.0 3.2 7.6 0.0 4.0 4 1 0 4 4 4 0 MFS_1 like family NpwBP PF12622.2 KZN93927.1 - 0.019 15.4 2.1 0.019 15.4 1.4 1.9 2 0 0 2 2 2 0 mRNA biogenesis factor MIT PF04212.13 KZN93929.1 - 0.0007 19.4 0.1 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Aminotran_1_2 PF00155.16 KZN93930.1 - 1.1e-43 149.5 0.0 1.3e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_11 PF13414.1 KZN93931.1 - 5.7e-09 35.4 7.6 0.00024 20.7 0.1 4.4 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 KZN93931.1 - 8.5e-09 34.6 13.5 0.0031 17.3 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KZN93931.1 - 4.6e-07 29.6 3.2 0.0006 19.6 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KZN93931.1 - 8.2e-06 25.2 4.6 0.11 12.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KZN93931.1 - 0.00052 20.3 7.3 0.019 15.3 0.0 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN93931.1 - 0.0011 19.6 15.3 0.04 14.5 0.0 6.1 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KZN93931.1 - 0.0012 19.2 9.8 2.1 9.2 0.2 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KZN93931.1 - 0.003 17.6 1.3 1.6e+02 2.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KZN93931.1 - 0.046 14.1 4.4 9.3 7.0 0.1 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN93931.1 - 0.17 11.7 5.0 20 5.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN93931.1 - 0.21 11.4 1.1 11 6.1 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KZN93933.1 - 1.9e-07 30.2 0.3 3.4e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN93933.1 - 0.0018 18.1 11.3 0.0028 17.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KZN93934.1 - 4.3 5.4 23.7 6.6 4.8 16.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Imm12 PF15589.1 KZN93939.1 - 0.49 10.1 3.2 17 5.1 0.1 2.8 1 1 1 2 2 2 0 Immunity protein 12 RINGv PF12906.2 KZN93942.1 - 0.0002 21.3 6.3 0.0005 20.0 4.4 1.8 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN93942.1 - 0.00061 19.5 8.4 0.001 18.8 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN93942.1 - 0.0096 16.0 3.4 0.019 15.0 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger DUF3330 PF11809.3 KZN93942.1 - 0.032 14.0 0.1 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN93942.1 - 0.63 10.1 7.2 1.2 9.1 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KZN93942.1 - 2.5 8.1 6.4 5.9 6.9 4.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Nop14 PF04147.7 KZN93943.1 - 0.0014 16.6 40.7 0.0017 16.4 28.2 1.0 1 0 0 1 1 1 1 Nop14-like family Tim54 PF11711.3 KZN93943.1 - 0.02 13.4 17.0 0.024 13.2 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 KZN93943.1 - 0.039 12.4 41.5 0.046 12.2 28.7 1.1 1 0 0 1 1 1 0 Daxx Family RNA_polI_A34 PF08208.6 KZN93943.1 - 0.33 10.5 30.3 0.37 10.4 21.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 KZN93943.1 - 0.44 8.5 33.3 0.53 8.2 23.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.1 KZN93943.1 - 0.5 9.5 14.9 0.57 9.3 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AUX_IAA PF02309.11 KZN93943.1 - 0.67 9.6 8.6 0.89 9.2 6.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF966 PF06136.8 KZN93943.1 - 0.78 9.1 10.1 0.81 9.0 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SMN PF06003.7 KZN93943.1 - 1.3 8.0 10.7 1.5 7.8 7.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SAPS PF04499.10 KZN93943.1 - 1.4 7.4 17.3 1.6 7.2 12.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BSMAP PF12280.3 KZN93943.1 - 1.6 8.5 9.0 2 8.2 6.2 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein CENP-T PF15511.1 KZN93943.1 - 1.7 7.7 27.6 2.1 7.5 19.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bud13 PF09736.4 KZN93943.1 - 2.6 8.3 23.6 3.4 7.9 16.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Spore_coat_CotO PF14153.1 KZN93943.1 - 3.1 7.2 35.1 3.8 6.9 24.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MDM1 PF15501.1 KZN93943.1 - 3.3 6.5 21.8 3.9 6.2 15.1 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Paf1 PF03985.8 KZN93943.1 - 3.7 6.1 43.6 4.4 5.9 30.2 1.1 1 0 0 1 1 1 0 Paf1 SpoIIP PF07454.6 KZN93943.1 - 4.2 6.4 16.0 5.2 6.1 11.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Utp14 PF04615.8 KZN93943.1 - 5.1 5.1 30.8 6.3 4.8 21.4 1.0 1 0 0 1 1 1 0 Utp14 protein CKAP2_C PF15297.1 KZN93943.1 - 5.7 5.6 24.1 6.7 5.4 16.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Herpes_DNAp_acc PF04929.7 KZN93943.1 - 6.2 5.6 11.3 7.3 5.4 7.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Lin-8 PF03353.10 KZN93943.1 - 6.2 6.0 20.3 7.1 5.8 14.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PLRV_ORF5 PF01690.12 KZN93943.1 - 7.2 5.6 17.0 8.2 5.4 11.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peptidase_S64 PF08192.6 KZN93943.1 - 9.3 4.4 9.4 9.6 4.4 6.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Dimer_Tnp_hAT PF05699.9 KZN93944.1 - 9.6e-14 50.7 0.1 1.3e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KZN93944.1 - 5.6e-06 26.2 0.5 1.5e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Hydrophobin PF01185.13 KZN93945.1 - 6.5e-05 23.2 7.7 9.8e-05 22.7 5.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN93945.1 - 0.014 15.5 3.0 0.014 15.5 2.0 2.2 2 0 0 2 2 2 0 Granulin Defensin_beta PF00711.14 KZN93945.1 - 0.19 11.7 0.3 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Beta defensin RNase_H PF00075.19 KZN93946.1 - 1.4e-05 25.4 0.1 3.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 KZN93946.1 - 0.0052 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrophobin PF01185.13 KZN93947.1 - 7.2e-05 23.1 8.0 0.00011 22.5 5.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN93947.1 - 0.014 15.5 3.0 0.014 15.5 2.0 2.2 2 0 0 2 2 2 0 Granulin Defensin_beta PF00711.14 KZN93947.1 - 0.19 11.7 0.3 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Beta defensin Hydrophobin PF01185.13 KZN93948.1 - 9.2e-05 22.8 7.2 0.00014 22.2 5.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN93948.1 - 0.012 15.7 2.9 0.012 15.7 2.0 2.2 2 0 0 2 2 2 0 Granulin Hydrophobin PF01185.13 KZN93949.1 - 5.6e-06 26.7 7.0 8.3e-06 26.1 4.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KZN93949.1 - 0.0037 17.3 2.4 0.0037 17.3 1.6 2.2 2 0 0 2 2 2 1 Granulin zf-RING_2 PF13639.1 KZN93952.1 - 0.0028 17.4 10.1 0.0046 16.7 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN93952.1 - 0.0042 17.1 4.9 0.0063 16.5 3.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KZN93952.1 - 0.12 12.2 1.7 0.18 11.6 1.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KZN93952.1 - 0.23 11.5 11.2 0.4 10.7 7.7 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KZN93952.1 - 0.73 9.5 9.7 2.7 7.7 7.0 1.7 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.1 KZN93952.1 - 0.76 9.8 7.9 1.3 9.0 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN93953.1 - 1.2e-45 153.7 10.3 2.3e-13 50.3 0.9 5.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KZN93953.1 - 4.1e-39 130.4 20.9 2.9e-08 33.1 0.0 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KZN93953.1 - 6.3e-34 115.2 19.6 3.6e-12 46.0 0.1 8.0 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN93953.1 - 2e-31 107.8 17.9 2e-07 31.3 0.1 8.2 1 1 8 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN93953.1 - 1.6e-29 98.9 16.7 1.3e-07 31.1 0.1 9.4 10 0 0 10 10 10 7 Ankyrin repeat F-box-like PF12937.2 KZN93953.1 - 2.4e-05 23.9 0.2 2.4e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN93953.1 - 0.00014 21.4 0.2 0.00025 20.6 0.1 1.4 1 0 0 1 1 1 1 F-box domain Mitofilin PF09731.4 KZN93954.1 - 0.078 11.6 0.5 0.15 10.6 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF360 PF04020.8 KZN93955.1 - 0.55 10.6 7.7 0.036 14.4 1.6 1.7 2 0 0 2 2 2 0 Membrane protein of unknown function VIT1 PF01988.14 KZN93955.1 - 4.6 6.6 7.3 0.13 11.6 0.7 1.6 2 0 0 2 2 2 0 VIT family Phageshock_PspG PF09583.5 KZN93955.1 - 5.1 7.2 8.0 12 6.0 0.4 2.8 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) Kdo PF06293.9 KZN93956.1 - 3.5e-06 26.2 0.1 7.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN93956.1 - 0.00022 20.4 0.3 0.00053 19.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN93956.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 3.8 3 1 1 4 4 4 1 Phosphotransferase enzyme family CDC45 PF02724.9 KZN93956.1 - 0.4 8.6 1.4 0.58 8.1 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4096 PF13340.1 KZN93957.1 - 0.068 13.0 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) zf-BED PF02892.10 KZN93957.1 - 1.8 8.4 5.7 0.9 9.3 1.5 2.1 2 0 0 2 2 2 0 BED zinc finger GAF_3 PF13492.1 KZN93959.1 - 2.2e-05 24.5 1.1 3.1 7.9 0.7 4.6 1 1 0 1 1 1 1 GAF domain Ribosomal_L22 PF00237.14 KZN93959.1 - 0.0086 16.0 0.0 15 5.6 0.0 3.6 1 1 1 2 2 2 2 Ribosomal protein L22p/L17e SseB_C PF14581.1 KZN93959.1 - 0.52 10.1 4.3 41 4.0 0.1 3.4 1 1 3 4 4 4 0 SseB protein C-terminal domain UAF_Rrn10 PF05234.6 KZN93959.1 - 1.4 8.9 18.4 51 3.9 0.2 6.3 2 1 5 7 7 7 0 UAF complex subunit Rrn10 DUF2162 PF09930.4 KZN93961.1 - 0.056 12.5 0.0 0.061 12.4 0.0 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Zn_clus PF00172.13 KZN93962.1 - 1.1e-08 34.7 13.3 2.4e-08 33.7 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN93962.1 - 0.00018 20.4 0.1 0.00054 18.9 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRN7 PF11781.3 KZN93962.1 - 0.85 9.1 7.6 1.7 8.1 5.3 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 TPR_8 PF13181.1 KZN93963.1 - 0.097 12.5 0.1 21 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 KZN93963.1 - 3.5 7.5 10.4 7 6.6 0.0 4.5 4 1 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Metaviral_G PF09595.5 KZN93964.1 - 0.19 11.3 1.6 0.25 10.9 1.1 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein Ank_2 PF12796.2 KZN93965.1 - 1.2e-70 233.8 13.8 2.8e-16 59.6 0.0 6.0 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KZN93965.1 - 2.9e-52 171.9 24.0 6.1e-07 28.9 0.0 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 KZN93965.1 - 4.7e-51 169.6 22.7 8.7e-10 38.5 0.1 10.8 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN93965.1 - 4.8e-47 157.5 16.9 3.2e-07 30.6 0.0 8.7 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN93965.1 - 1.3e-40 133.3 17.6 0.0013 18.8 0.0 12.3 13 0 0 13 13 13 11 Ankyrin repeat F-box-like PF12937.2 KZN93965.1 - 0.00049 19.7 0.1 0.00091 18.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN93965.1 - 0.034 13.8 0.1 0.082 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain MRP-S28 PF10213.4 KZN93967.1 - 0.035 14.1 0.1 9.5 6.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit protein Dimer_Tnp_hAT PF05699.9 KZN93968.1 - 1.5e-10 40.5 0.0 3.9e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KZN93968.1 - 9.6e-06 25.2 2.9 2.3e-05 24.0 2.0 1.6 1 0 0 1 1 1 1 BED zinc finger RbsD_FucU PF05025.8 KZN93969.1 - 0.0097 16.2 0.1 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 RbsD / FucU transport protein family Sigma70_ner PF04546.8 KZN93969.1 - 0.057 13.0 4.3 0.07 12.7 3.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region AF1Q PF15017.1 KZN93969.1 - 0.8 9.6 5.8 0.36 10.7 2.3 1.7 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator Virul_fac_BrkB PF03631.10 KZN93971.1 - 0.096 12.0 0.5 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Urocanase PF01175.13 KZN93972.1 - 0.16 9.9 0.0 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 Urocanase zf-C2H2 PF00096.21 KZN93973.1 - 1.9e-09 37.2 12.5 0.00018 21.6 2.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN93973.1 - 4.7e-06 26.6 12.4 1.1e-05 25.5 1.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN93973.1 - 2.9e-05 24.0 9.9 0.013 15.7 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger ZF-HD_dimer PF04770.7 KZN93973.1 - 0.017 15.1 4.4 0.036 14.1 0.4 2.3 1 1 1 2 2 2 0 ZF-HD protein dimerisation region CHORD PF04968.7 KZN93973.1 - 0.1 12.8 2.5 8.1 6.7 0.2 2.2 1 1 1 2 2 2 0 CHORD DUF230 PF03003.11 KZN93973.1 - 0.5 9.8 3.4 0.92 9.0 0.3 2.2 1 1 1 2 2 2 0 Poxvirus proteins of unknown function zf-met PF12874.2 KZN93973.1 - 0.53 10.5 7.2 0.72 10.1 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KZN93973.1 - 7.2 6.8 7.0 11 6.3 0.5 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNase_T PF00929.19 KZN93976.1 - 2.9e-20 73.2 0.0 4.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KZN93976.1 - 2.6e-05 23.8 0.0 0.00043 19.8 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease MaoC_dehydratas PF01575.14 KZN93976.1 - 0.04 13.2 0.1 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain APH PF01636.18 KZN93978.1 - 9.8e-18 64.7 0.0 2.5e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family SdpI PF13630.1 KZN93981.1 - 0.09 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family THOC7 PF05615.8 KZN93982.1 - 0.23 11.7 2.4 0.16 12.2 0.6 1.5 2 0 0 2 2 2 0 Tho complex subunit 7 TACC PF05010.9 KZN93983.1 - 0.0025 17.5 3.5 0.0038 17.0 2.4 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) TFCD_C PF12612.3 KZN93983.1 - 0.069 12.5 0.4 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF1604 PF07713.8 KZN93983.1 - 0.079 12.7 0.2 0.31 10.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1604) APG6 PF04111.7 KZN93983.1 - 0.11 11.4 5.6 0.14 11.1 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BRE1 PF08647.6 KZN93983.1 - 0.14 12.1 8.3 0.22 11.5 5.5 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase FUSC PF04632.7 KZN93983.1 - 7.3 4.8 6.3 9.2 4.5 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Chitin_bind_3 PF03067.10 KZN93985.1 - 0.0035 17.6 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain DUF4625 PF15418.1 KZN93985.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) FxsA PF04186.8 KZN93987.1 - 0.0099 15.4 1.6 0.65 9.6 0.0 2.7 2 1 1 3 3 3 2 FxsA cytoplasmic membrane protein SirB PF04247.7 KZN93987.1 - 0.051 13.3 4.0 0.17 11.5 1.4 2.5 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB Patatin PF01734.17 KZN93988.1 - 3.4e-21 76.0 0.3 8.9e-21 74.7 0.2 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN93988.1 - 0.0012 18.4 5.2 0.0045 16.6 3.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN93988.1 - 0.0028 17.6 8.7 0.0086 16.0 6.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN93988.1 - 0.0049 16.5 7.2 0.014 15.1 5.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN93988.1 - 0.13 12.0 9.0 0.39 10.5 6.2 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-JAB PF14464.1 KZN93991.1 - 0.0025 17.3 0.7 0.0045 16.5 0.4 1.4 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2706 PF10913.3 KZN93993.1 - 0.27 10.8 1.7 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) DUF3723 PF12520.3 KZN93994.1 - 1.9e-33 115.7 0.2 2.2e-27 95.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF1129 PF06570.6 KZN93995.1 - 0.43 9.8 3.6 0.68 9.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TauD PF02668.11 KZN93997.1 - 0.055 13.1 0.1 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family IncA PF04156.9 KZN93997.1 - 0.41 10.2 8.5 0.53 9.8 5.9 1.2 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 KZN93997.1 - 0.53 8.6 4.2 0.65 8.3 2.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 KZN93997.1 - 1.4 7.8 8.7 1.6 7.7 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GPI-anchored PF10342.4 KZN94000.1 - 2.4e-19 69.6 1.8 2.4e-19 69.6 1.2 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIF_alpha PF05793.7 KZN94000.1 - 0.92 7.8 4.9 1.3 7.3 3.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RAP1 PF07218.6 KZN94000.1 - 4.1 5.3 12.1 5.1 5.0 8.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_viral_N PF00242.12 KZN94000.1 - 9.2 5.1 9.9 12 4.7 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SSP160 PF06933.6 KZN94000.1 - 9.3 4.0 27.9 14 3.5 19.3 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-box PF00646.28 KZN94001.1 - 9.6e-05 21.9 0.2 0.00035 20.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KZN94001.1 - 0.0001 21.9 0.1 0.00036 20.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.7 KZN94002.1 - 2.6e-26 91.5 1.4 4.9e-26 90.6 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN94002.1 - 6.6e-23 80.6 0.0 1.1e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KZN94002.1 - 1.1e-06 28.1 0.0 4.3e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated NAD_binding_7 PF13241.1 KZN94002.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KZN94002.1 - 0.021 13.8 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.1 KZN94002.1 - 0.023 15.6 0.0 0.038 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KZN94002.1 - 0.075 13.1 0.2 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 KZN94002.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3295 PF11702.3 KZN94004.1 - 7e-164 546.5 16.3 8.6e-164 546.2 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KZN94004.1 - 1.5e-12 46.8 1.6 4e-12 45.4 1.1 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Penicillinase_R PF03965.11 KZN94004.1 - 0.15 12.1 0.2 44 4.2 0.0 2.9 3 0 0 3 3 3 0 Penicillinase repressor MipZ PF09140.6 KZN94005.1 - 0.11 11.6 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 ATPase MipZ DUF3435 PF11917.3 KZN94007.1 - 5.7e-161 535.8 0.3 1.4e-160 534.6 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KZN94007.1 - 0.12 12.7 2.3 0.63 10.5 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN94007.1 - 0.47 10.9 2.9 3.5 8.1 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger OmpH PF03938.9 KZN94007.1 - 7.5 6.4 15.9 6.7 6.6 5.3 3.1 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Pkinase_Tyr PF07714.12 KZN94009.1 - 0.00031 19.9 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KZN94009.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-rbx1 PF12678.2 KZN94010.1 - 0.0027 17.7 6.2 0.0067 16.5 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KZN94010.1 - 0.0045 16.7 12.6 0.0084 15.9 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain DUF3330 PF11809.3 KZN94010.1 - 0.014 15.2 0.1 0.05 13.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) RINGv PF12906.2 KZN94010.1 - 0.051 13.6 13.3 0.1 12.6 9.2 1.5 1 0 0 1 1 1 0 RING-variant domain GAF_3 PF13492.1 KZN94015.1 - 0.0031 17.6 2.8 53 3.9 1.9 5.0 1 1 0 1 1 1 0 GAF domain CLASP_N PF12348.3 KZN94015.1 - 1.1 8.6 11.9 37 3.5 0.0 6.6 2 2 4 7 7 7 0 CLASP N terminal Herpes_LMP1 PF05297.6 KZN94015.1 - 4.6 6.0 7.9 6.5 5.5 1.9 2.7 1 1 0 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) PTR2 PF00854.16 KZN94016.1 - 1.6e-11 43.6 0.3 1.4e-08 33.9 0.0 2.0 2 0 0 2 2 2 2 POT family NIPSNAP PF07978.8 KZN94016.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NIPSNAP Silic_transp PF03842.8 KZN94016.1 - 0.13 10.3 0.0 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Silicon transporter PQ-loop PF04193.9 KZN94017.1 - 1.1e-33 114.5 10.6 9.3e-19 66.7 1.0 3.2 3 0 0 3 3 3 2 PQ loop repeat MARVEL PF01284.18 KZN94017.1 - 0.87 9.4 13.4 0.3 10.8 6.7 2.3 1 1 0 1 1 1 0 Membrane-associating domain MRAP PF15183.1 KZN94018.1 - 0.11 12.1 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PALP PF00291.20 KZN94019.1 - 8.8e-24 84.2 0.0 1.7e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cys_Met_Meta_PP PF01053.15 KZN94020.1 - 4.4e-128 426.8 0.0 5.1e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KZN94020.1 - 4.2e-10 39.1 0.0 6.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KZN94020.1 - 8.7e-09 34.8 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KZN94020.1 - 2.4e-06 26.5 0.1 5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KZN94020.1 - 0.00042 19.5 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KZN94020.1 - 0.026 13.2 0.1 0.053 12.2 0.0 1.5 2 0 0 2 2 2 0 Glycine cleavage system P-protein PTR2 PF00854.16 KZN94021.1 - 5e-29 101.2 8.7 1.1e-28 100.1 6.0 1.5 1 1 0 1 1 1 1 POT family ATP-grasp_4 PF13535.1 KZN94022.1 - 1.6e-19 70.3 0.0 4e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN94022.1 - 9.4e-07 27.8 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Fungal_trans PF04082.13 KZN94023.1 - 3.5e-07 29.3 0.3 5.6e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank PF00023.25 KZN94024.1 - 2.4e-22 77.5 6.8 2.4e-09 36.5 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KZN94024.1 - 5.3e-19 68.3 0.5 1.3e-10 41.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN94024.1 - 4.5e-13 48.0 1.5 7.8e-06 25.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN94024.1 - 4.9e-13 48.8 3.0 2.9e-05 24.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94024.1 - 1.7e-10 41.1 0.6 1.5e-05 25.3 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HLH PF00010.21 KZN94025.1 - 2e-05 24.1 0.2 3.8e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ank PF00023.25 KZN94029.1 - 4.5e-23 79.8 7.7 2.4e-09 36.5 0.3 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 KZN94029.1 - 2.3e-19 69.4 1.9 4.8e-11 42.8 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KZN94029.1 - 5.9e-17 60.0 2.0 3.3e-08 32.9 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KZN94029.1 - 8e-14 51.3 4.1 1.2e-07 31.6 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94029.1 - 1.9e-13 50.4 0.3 1.5e-07 31.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ATP-grasp_4 PF13535.1 KZN94030.1 - 3.8e-18 65.8 0.0 3.2e-16 59.6 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KZN94030.1 - 0.00036 19.3 0.0 0.051 12.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KZN94030.1 - 0.04 13.3 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus RVT_1 PF00078.22 KZN94031.1 - 9.6e-14 51.2 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 KZN94031.1 - 6e-10 39.1 0.0 9.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KZN94031.1 - 1.8e-06 28.3 0.0 3.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KZN94031.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KZN94031.1 - 0.044 13.7 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2486 PF10667.4 KZN94035.1 - 0.031 14.8 2.1 0.037 14.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) CP2 PF04516.10 KZN94036.1 - 1.9e-63 213.6 0.0 2.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor zf-C2H2 PF00096.21 KZN94037.1 - 3.5e-05 23.8 10.0 0.056 13.8 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN94037.1 - 0.0001 22.3 7.8 0.046 14.0 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN94037.1 - 0.00022 21.3 0.1 0.00022 21.3 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double domain Ifi-6-16 PF06140.8 KZN94038.1 - 0.0041 16.8 30.4 0.0041 16.8 21.0 2.3 1 1 1 2 2 2 1 Interferon-induced 6-16 family H_PPase PF03030.11 KZN94039.1 - 0.031 12.5 0.3 0.041 12.1 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase YbhQ PF11076.3 KZN94039.1 - 0.11 12.0 0.3 4.5 6.8 0.1 2.1 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Kdo PF06293.9 KZN94044.1 - 0.00068 18.7 0.1 0.001 18.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KZN94044.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KZN94044.1 - 0.0087 15.8 0.2 0.019 14.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KZN94044.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.6 KZN94044.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) NPP PF08384.5 KZN94046.1 - 0.059 13.0 0.3 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region HATPase_c_3 PF13589.1 KZN94047.1 - 8.2e-06 25.5 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KZN94047.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CLASP_N PF12348.3 KZN94048.1 - 0.0049 16.2 0.3 0.18 11.1 0.1 2.2 2 0 0 2 2 2 2 CLASP N terminal Ank_2 PF12796.2 KZN94049.1 - 4.6e-15 55.7 0.1 7.4e-13 48.6 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94049.1 - 5.8e-14 51.1 1.3 3e-07 29.9 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KZN94049.1 - 1.9e-10 40.6 1.1 1.9e-07 31.0 0.4 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94049.1 - 8e-10 38.9 0.2 0.0012 19.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94049.1 - 3.4e-08 32.9 0.3 0.00018 21.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat VIT1 PF01988.14 KZN94050.1 - 0.0038 16.7 2.6 0.0038 16.7 1.8 1.8 2 0 0 2 2 2 1 VIT family zf-RING_2 PF13639.1 KZN94052.1 - 0.0015 18.3 9.4 0.0027 17.5 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN94052.1 - 0.0023 17.9 10.2 0.0046 16.9 7.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN94052.1 - 0.0096 16.0 3.7 0.022 14.8 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN94052.1 - 1.3 9.0 7.9 2.8 8.0 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KZN94052.1 - 2.9 7.9 7.4 6 6.9 5.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Ank_2 PF12796.2 KZN94053.1 - 1.9e-91 300.5 18.4 1.1e-14 54.5 0.1 6.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94053.1 - 3.1e-50 165.5 20.3 3e-06 26.7 0.0 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 KZN94053.1 - 9.8e-48 159.1 20.7 7.4e-10 38.7 0.0 10.5 3 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94053.1 - 6.2e-46 153.9 17.6 4.1e-07 30.3 0.0 8.5 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94053.1 - 1.3e-39 130.2 15.6 7.1e-05 22.6 0.0 12.3 13 0 0 13 13 13 11 Ankyrin repeat F-box-like PF12937.2 KZN94053.1 - 0.00047 19.8 0.1 0.00091 18.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN94053.1 - 0.031 13.9 0.1 0.082 12.5 0.1 1.8 1 0 0 1 1 1 0 F-box domain Chibby PF14645.1 KZN94054.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Chibby family NEMO PF11577.3 KZN94055.1 - 0.64 9.8 7.2 2.2 8.1 5.0 1.8 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO Syntaxin PF00804.20 KZN94057.1 - 0.014 15.5 2.8 0.019 15.1 1.8 1.7 1 1 0 1 1 1 0 Syntaxin PRKCSH-like PF12999.2 KZN94057.1 - 0.11 12.0 0.2 0.22 11.1 0.0 1.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like SlyX PF04102.7 KZN94057.1 - 1.1 9.7 3.2 3.1 8.2 0.4 2.6 3 0 0 3 3 3 0 SlyX TACC PF05010.9 KZN94058.1 - 0.00062 19.5 1.8 0.00092 19.0 1.3 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) zf-C4H2 PF10146.4 KZN94058.1 - 0.0023 17.9 0.1 0.0028 17.6 0.1 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein TFCD_C PF12612.3 KZN94058.1 - 0.063 12.7 0.4 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF1604 PF07713.8 KZN94058.1 - 0.075 12.8 0.3 0.31 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1604) APG6 PF04111.7 KZN94058.1 - 0.085 11.8 5.4 0.1 11.6 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BRE1 PF08647.6 KZN94058.1 - 0.12 12.3 8.3 0.22 11.5 5.5 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase FUSC PF04632.7 KZN94058.1 - 7.6 4.8 6.5 9.6 4.4 4.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4625 PF15418.1 KZN94060.1 - 0.00097 19.2 0.0 0.0027 17.8 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) Glyco_hydro_61 PF03443.9 KZN94060.1 - 0.038 13.7 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Pkinase PF00069.20 KZN94061.1 - 0.06 12.4 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SirB PF04247.7 KZN94063.1 - 0.031 13.9 3.5 0.088 12.5 0.9 2.4 1 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB FxsA PF04186.8 KZN94063.1 - 0.089 12.4 2.4 0.95 9.0 0.0 2.6 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Patatin PF01734.17 KZN94064.1 - 2.6e-21 76.5 1.6 3.5e-21 76.0 0.3 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN94064.1 - 0.0013 18.3 5.2 0.0045 16.6 3.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN94064.1 - 0.0026 17.7 8.7 0.0086 16.0 6.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN94064.1 - 0.0048 16.6 7.2 0.014 15.1 5.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN94064.1 - 0.14 12.0 9.0 0.39 10.5 6.2 1.9 1 0 0 1 1 1 0 Ring finger domain BAR_2 PF10455.4 KZN94066.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Prok-JAB PF14464.1 KZN94067.1 - 0.0025 17.3 0.7 0.0045 16.5 0.4 1.4 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2706 PF10913.3 KZN94069.1 - 0.49 10.0 3.1 0.92 9.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2706) DUF3723 PF12520.3 KZN94070.1 - 6.3e-60 203.1 0.3 4.3e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) HlyIII PF03006.15 KZN94071.1 - 0.032 13.6 9.8 0.042 13.2 6.8 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF1129 PF06570.6 KZN94071.1 - 0.26 10.5 2.1 0.41 9.9 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Myosin_tail_1 PF01576.14 KZN94073.1 - 1.6e-05 22.8 1.7 2e-05 22.5 1.2 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 KZN94073.1 - 0.0001 21.9 1.0 0.0001 21.9 0.7 1.4 2 0 0 2 2 2 1 IncA protein ATG16 PF08614.6 KZN94073.1 - 0.0021 17.8 1.6 0.0031 17.3 1.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WEMBL PF05701.6 KZN94073.1 - 0.0066 14.9 3.1 0.0091 14.5 2.1 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 KZN94073.1 - 0.0081 16.0 2.8 0.014 15.2 2.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 KZN94073.1 - 0.0085 15.3 0.9 0.011 14.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF641 PF04859.7 KZN94073.1 - 0.013 15.2 1.1 0.025 14.3 0.7 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 KZN94073.1 - 0.014 15.2 2.4 0.024 14.4 1.7 1.3 1 0 0 1 1 1 0 Tropomyosin like Herpes_UL6 PF01763.11 KZN94073.1 - 0.024 12.8 1.7 0.031 12.4 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Rootletin PF15035.1 KZN94073.1 - 0.03 14.2 1.0 0.041 13.8 0.7 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF972 PF06156.8 KZN94073.1 - 0.071 13.4 1.8 0.12 12.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 KZN94073.1 - 0.073 12.9 3.9 0.13 12.1 2.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PEP-utilisers_N PF05524.8 KZN94073.1 - 0.075 12.8 1.7 0.12 12.1 1.2 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal HAUS6_N PF14661.1 KZN94073.1 - 0.097 12.0 1.1 0.13 11.5 0.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2968 PF11180.3 KZN94073.1 - 0.098 12.0 1.1 0.14 11.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TBPIP PF07106.8 KZN94073.1 - 0.1 12.1 1.4 0.16 11.5 0.9 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Imm2 PF14426.1 KZN94073.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm2 DUF1640 PF07798.6 KZN94073.1 - 0.27 11.2 4.1 1.5 8.8 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Reo_sigmaC PF04582.7 KZN94073.1 - 0.81 8.8 4.0 1 8.4 2.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 KZN94073.1 - 1.3 8.9 7.9 0.2 11.5 2.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 KZN94073.1 - 1.4 8.8 5.9 4.1 7.2 0.6 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-T PF15511.1 KZN94075.1 - 0.021 14.0 10.0 0.024 13.9 6.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T HrpA_pilin PF09589.5 KZN94075.1 - 0.23 11.9 3.2 0.13 12.7 0.6 1.7 2 1 0 2 2 2 0 HrpA pilus formation protein RNase_T PF00929.19 KZN94077.1 - 1.4e-21 77.4 0.0 2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KZN94077.1 - 1.3e-05 24.7 0.0 0.00023 20.6 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease MaoC_dehydratas PF01575.14 KZN94077.1 - 0.06 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Kdo PF06293.9 KZN94078.1 - 3.4e-06 26.2 0.0 6.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KZN94078.1 - 0.00034 19.8 0.1 0.0009 18.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KZN94078.1 - 0.003 17.3 9.8 0.0039 16.9 0.1 3.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Elf1 PF05129.8 KZN94079.1 - 0.028 14.0 0.5 0.038 13.6 0.4 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SRF-TF PF00319.13 KZN94079.1 - 0.035 13.3 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) SufE PF02657.10 KZN94079.1 - 0.043 13.4 0.1 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Fe-S metabolism associated domain Dimer_Tnp_hAT PF05699.9 KZN94080.1 - 3.7e-11 42.4 0.0 6.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.21 KZN94082.1 - 2.6e-09 36.8 12.4 0.00025 21.2 2.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN94082.1 - 3.2e-06 27.1 12.8 6.8e-06 26.1 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN94082.1 - 1.7e-05 24.7 10.0 0.013 15.7 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger ZF-HD_dimer PF04770.7 KZN94082.1 - 0.05 13.6 4.2 0.12 12.4 0.3 2.3 1 1 1 2 2 2 0 ZF-HD protein dimerisation region CHORD PF04968.7 KZN94082.1 - 0.064 13.4 2.6 4.7 7.5 0.2 2.2 1 1 1 2 2 2 0 CHORD zf-met PF12874.2 KZN94082.1 - 0.31 11.3 6.9 0.72 10.1 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF230 PF03003.11 KZN94082.1 - 0.55 9.7 3.5 0.86 9.1 0.3 2.1 1 1 1 2 2 2 0 Poxvirus proteins of unknown function zf-C2H2_jaz PF12171.3 KZN94082.1 - 3.2 8.0 6.8 11 6.3 0.5 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNase_T PF00929.19 KZN94086.1 - 1.4e-21 77.4 0.0 2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KZN94086.1 - 1.3e-05 24.7 0.0 0.00023 20.6 0.0 2.8 2 1 0 2 2 2 1 3'-5' exonuclease MaoC_dehydratas PF01575.14 KZN94086.1 - 0.06 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Pkinase PF00069.20 KZN94088.1 - 6.7e-10 38.5 0.0 1e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN94088.1 - 3.3e-06 26.3 0.0 1.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KZN94088.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN94088.1 - 0.021 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN94088.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AAA PF00004.24 KZN94089.1 - 1.2e-19 70.7 0.6 1.1e-17 64.4 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN94089.1 - 0.00013 22.7 0.3 0.00066 20.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KZN94089.1 - 0.011 16.0 0.1 0.056 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KZN94089.1 - 0.018 15.1 2.1 4.6 7.4 0.0 3.2 2 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KZN94089.1 - 0.045 13.7 0.1 0.4 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 KZN94089.1 - 0.053 13.4 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KZN94089.1 - 0.067 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 KZN94089.1 - 0.11 12.0 0.2 0.92 8.9 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 KZN94089.1 - 0.13 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain 7TM_GPCR_Srw PF10324.4 KZN94090.1 - 0.73 8.8 7.8 0.92 8.5 3.8 2.2 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF202 PF02656.10 KZN94090.1 - 3.4 7.9 9.5 45 4.3 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) zf-RING_2 PF13639.1 KZN94091.1 - 0.001 18.8 8.9 0.0019 17.9 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN94091.1 - 0.0022 17.9 9.4 0.0047 16.9 6.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 KZN94091.1 - 0.0079 16.2 3.4 0.019 15.0 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KZN94091.1 - 0.95 9.5 7.5 2.1 8.4 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN94092.1 - 2.6e-85 280.8 13.9 3.9e-14 52.7 0.0 6.0 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94092.1 - 9.9e-48 157.6 18.4 8.1e-07 28.5 0.0 11.5 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KZN94092.1 - 4.6e-46 153.7 17.2 8.5e-10 38.5 0.0 9.9 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94092.1 - 3.4e-41 138.8 17.1 3.2e-07 30.6 0.1 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94092.1 - 9.6e-38 124.4 13.6 0.00012 21.9 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat F-box-like PF12937.2 KZN94092.1 - 0.00043 19.9 0.1 0.00083 19.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN94092.1 - 0.034 13.8 0.7 0.075 12.7 0.1 1.9 2 0 0 2 2 2 0 F-box domain MIT PF04212.13 KZN94094.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 KZN94094.1 - 0.018 14.6 0.1 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KZN94094.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KZN94094.1 - 0.048 13.4 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KZN94094.1 - 0.12 12.1 0.1 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 KZN94094.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 TPR repeat Ank_2 PF12796.2 KZN94095.1 - 1.1e-94 310.8 20.0 2.2e-15 56.7 0.1 9.8 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94095.1 - 1e-84 274.3 30.5 3.3e-08 32.9 0.1 18.5 17 2 1 18 18 18 15 Ankyrin repeat Ank_4 PF13637.1 KZN94095.1 - 1e-68 226.6 12.4 4.6e-09 36.5 0.0 12.2 8 4 5 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94095.1 - 2.8e-66 212.7 8.6 0.00028 20.8 0.0 17.8 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 KZN94095.1 - 2.3e-64 211.9 26.3 8.3e-09 35.4 0.1 12.9 7 5 7 14 14 14 13 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.3 KZN94095.1 - 3 8.0 6.9 15 5.7 0.1 4.7 5 0 0 5 5 5 0 Selenocysteine synthase N terminal DUF481 PF04338.7 KZN94096.1 - 0.00018 21.2 9.6 3.2 7.4 6.7 3.0 1 1 0 1 1 1 1 Protein of unknown function, DUF481 DUF1943 PF09172.6 KZN94096.1 - 0.0002 20.3 26.0 1.4e+03 -2.2 18.1 3.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2715 PF10895.3 KZN94096.1 - 0.44 10.0 38.7 1.5e+04 -21.8 26.8 5.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2715) DUF4419 PF14388.1 KZN94098.1 - 1.6e-107 359.1 0.1 1.9e-107 358.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4219 PF13961.1 KZN94101.1 - 5.6e-10 38.3 0.1 1e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 KZN94101.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1505 PF07403.6 KZN94103.1 - 0.3 11.0 8.0 0.3 11.0 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1505) DUF1517 PF07466.6 KZN94103.1 - 0.66 8.9 4.6 0.82 8.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Period_C PF12114.3 KZN94103.1 - 8.8 5.8 7.6 13 5.3 5.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF420 PF04238.7 KZN94105.1 - 0.094 12.6 3.9 0.19 11.6 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF420) VIT1 PF01988.14 KZN94108.1 - 0.049 13.1 1.9 0.056 12.9 1.3 1.2 1 0 0 1 1 1 0 VIT family CD20 PF04103.10 KZN94108.1 - 2.5 8.0 8.3 16 5.4 0.0 2.6 2 1 0 2 2 2 0 CD20-like family RINGv PF12906.2 KZN94109.1 - 0.00014 21.8 6.9 0.00036 20.4 4.8 1.8 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KZN94109.1 - 0.0013 18.4 9.5 0.0026 17.5 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KZN94109.1 - 0.021 14.9 4.8 0.055 13.5 3.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3330 PF11809.3 KZN94109.1 - 0.034 14.0 0.1 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 KZN94109.1 - 1.4 8.9 8.1 3.6 7.6 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KZN94110.1 - 1.1e-93 307.7 23.5 2.4e-16 59.8 0.1 5.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94110.1 - 2.7e-52 172.0 25.0 8.2e-07 28.5 0.0 12.5 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.1 KZN94110.1 - 5.9e-49 162.9 23.4 4.7e-10 39.3 0.1 10.4 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94110.1 - 2.2e-46 155.4 19.4 6.7e-07 29.6 0.1 8.8 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94110.1 - 4.2e-40 131.7 20.8 0.0012 18.8 0.0 12.7 13 0 0 13 13 13 10 Ankyrin repeat F-box-like PF12937.2 KZN94110.1 - 0.00046 19.8 0.2 0.00091 18.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN94110.1 - 0.033 13.8 0.1 0.082 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain Chibby PF14645.1 KZN94111.1 - 0.1 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Chibby family Prok-JAB PF14464.1 KZN94112.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.1 KZN94112.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 JAB-like toxin 1 DUF3723 PF12520.3 KZN94115.1 - 6.8e-47 160.1 6.2 7.4e-26 90.7 0.1 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) HlyIII PF03006.15 KZN94116.1 - 0.061 12.7 10.3 0.08 12.3 7.1 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF1129 PF06570.6 KZN94116.1 - 0.26 10.5 2.1 0.41 9.9 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4200 PF13863.1 KZN94119.1 - 0.24 11.3 7.8 0.35 10.8 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HrpA_pilin PF09589.5 KZN94120.1 - 0.025 15.0 0.5 0.045 14.1 0.4 1.4 1 0 0 1 1 1 0 HrpA pilus formation protein DUF1410 PF07198.6 KZN94121.1 - 0.019 15.2 0.0 0.031 14.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1410) Ank_2 PF12796.2 KZN94122.1 - 5.9e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94122.1 - 1.4e-14 53.0 0.3 1.6e-08 33.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KZN94122.1 - 1e-12 47.8 3.9 9.4e-09 35.2 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KZN94122.1 - 3.9e-12 46.3 0.8 7.5e-08 32.6 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94122.1 - 4e-10 38.9 0.3 2.2e-05 24.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3700 PF12481.3 KZN94123.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein LysM PF01476.15 KZN94124.1 - 4.3e-22 77.7 1.4 8.5e-07 28.7 0.1 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.7 KZN94124.1 - 0.0026 17.5 0.6 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Glyco_hydro_18 PF00704.23 KZN94126.1 - 5e-43 147.8 0.1 1.1e-42 146.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KZN94126.1 - 5.2e-30 103.2 1.9 1.2e-29 102.0 0.5 2.3 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KZN94126.1 - 1.8e-07 30.9 0.1 0.011 15.6 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KZN94126.1 - 9.5e-05 22.2 2.3 9.5e-05 22.2 1.6 3.3 2 0 0 2 2 2 1 Chitin recognition protein Peptidase_C97 PF05903.9 KZN94127.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Chibby PF14645.1 KZN94128.1 - 0.066 13.0 0.4 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Chibby family Tubulin_C PF03953.12 KZN94129.1 - 3.4e-44 149.9 0.1 5.1e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 KZN94129.1 - 1.1e-23 84.1 0.0 1.8e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin PF00091.20 KZN94130.1 - 8.1e-24 84.6 0.0 9.6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Abhydrolase_6 PF12697.2 KZN94131.1 - 1.7e-24 86.9 0.0 3e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KZN94131.1 - 5.7e-05 22.8 0.0 0.00011 21.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Con-6 PF10346.4 KZN94132.1 - 0.0033 16.8 0.3 1.1 8.6 0.0 2.5 2 1 0 2 2 2 2 Conidiation protein 6 BAR_2 PF10455.4 KZN94135.1 - 0.048 12.5 0.1 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Patatin PF01734.17 KZN94136.1 - 9.2e-21 74.7 0.4 3.2e-20 72.9 0.3 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN94136.1 - 0.0011 18.6 5.2 0.0044 16.6 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN94136.1 - 0.0023 17.9 8.7 0.0084 16.1 6.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN94136.1 - 0.0044 16.7 7.2 0.013 15.1 5.0 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN94136.1 - 0.11 12.3 9.0 0.38 10.6 6.2 2.0 1 0 0 1 1 1 0 Ring finger domain FxsA PF04186.8 KZN94137.1 - 0.083 12.5 3.3 1.8 8.1 0.0 2.9 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Pkinase PF00069.20 KZN94138.1 - 3.6e-05 23.0 0.0 5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN94138.1 - 0.039 13.0 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4625 PF15418.1 KZN94139.1 - 0.002 18.2 0.0 0.0056 16.7 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4625) TACC PF05010.9 KZN94141.1 - 0.00044 20.0 1.9 0.00067 19.4 1.4 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) zf-C4H2 PF10146.4 KZN94141.1 - 0.002 18.1 0.1 0.0026 17.8 0.1 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein TFCD_C PF12612.3 KZN94141.1 - 0.063 12.6 0.4 0.089 12.2 0.3 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF1604 PF07713.8 KZN94141.1 - 0.083 12.6 0.3 0.31 10.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1604) BRE1 PF08647.6 KZN94141.1 - 0.12 12.3 8.3 0.22 11.5 5.5 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase APG6 PF04111.7 KZN94141.1 - 0.17 10.8 6.4 0.21 10.6 4.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KZN94141.1 - 0.33 9.8 7.4 0.43 9.4 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KZN94141.1 - 6.3 5.0 6.3 8 4.7 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKCSH-like PF12999.2 KZN94142.1 - 0.087 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Dimer_Tnp_hAT PF05699.9 KZN94147.1 - 1.7e-10 40.3 0.0 4.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 KZN94147.1 - 9.7e-06 25.2 2.9 2.3e-05 24.0 2.0 1.6 1 0 0 1 1 1 1 BED zinc finger RbsD_FucU PF05025.8 KZN94148.1 - 0.0098 16.2 0.1 0.015 15.6 0.0 1.2 1 0 0 1 1 1 1 RbsD / FucU transport protein family Sigma70_ner PF04546.8 KZN94148.1 - 0.056 13.0 4.3 0.07 12.7 3.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Virul_fac_BrkB PF03631.10 KZN94150.1 - 0.004 16.5 1.2 0.006 15.9 0.8 1.2 1 0 0 1 1 1 1 Virulence factor BrkB Ferric_reduct PF01794.14 KZN94150.1 - 0.053 13.6 7.6 0.39 10.8 5.3 2.3 1 1 0 1 1 1 0 Ferric reductase like transmembrane component zf-C2H2 PF00096.21 KZN94152.1 - 3.7e-06 26.9 19.0 0.0013 18.8 2.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN94152.1 - 3e-05 24.0 10.9 3.8e-05 23.7 2.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN94152.1 - 0.0003 20.9 10.2 0.075 13.3 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KZN94152.1 - 0.032 14.4 5.7 3.4 7.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ZF-HD_dimer PF04770.7 KZN94152.1 - 0.18 11.9 4.2 0.53 10.3 0.2 2.6 1 1 1 2 2 2 0 ZF-HD protein dimerisation region RasGEF PF00617.14 KZN94154.1 - 0.001 18.7 0.0 0.013 15.2 0.0 2.5 1 1 0 1 1 1 1 RasGEF domain Zn_clus PF00172.13 KZN94157.1 - 9.9e-09 34.9 13.1 1.8e-08 34.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KZN94157.1 - 9.7e-05 21.3 0.1 0.00022 20.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRN7 PF11781.3 KZN94157.1 - 0.79 9.2 7.6 1.5 8.3 5.3 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 APH PF01636.18 KZN94158.1 - 7e-11 42.3 2.3 7.4e-10 38.9 1.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KZN94158.1 - 0.00087 18.9 0.1 0.00087 18.9 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF360 PF04020.8 KZN94159.1 - 5.9 7.2 9.0 5.1 7.4 4.2 2.5 1 1 1 2 2 2 0 Membrane protein of unknown function zf-RING_2 PF13639.1 KZN94160.1 - 0.00067 19.4 8.5 0.0013 18.5 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain RINGv PF12906.2 KZN94160.1 - 0.0023 17.9 9.5 0.0046 16.9 6.6 1.6 1 0 0 1 1 1 1 RING-variant domain DUF3330 PF11809.3 KZN94160.1 - 0.15 11.9 1.8 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3330) zf-rbx1 PF12678.2 KZN94160.1 - 0.48 10.5 8.9 0.032 14.3 2.6 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger Mitofilin PF09731.4 KZN94161.1 - 0.059 12.0 2.2 0.04 12.5 0.5 1.4 2 0 0 2 2 2 0 Mitochondrial inner membrane protein NEMO PF11577.3 KZN94161.1 - 0.38 10.5 3.8 0.83 9.4 2.6 1.5 1 1 0 1 1 1 0 NF-kappa-B essential modulator NEMO APH PF01636.18 KZN94162.1 - 3.3e-13 49.9 0.3 9.4e-13 48.4 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KZN94162.1 - 0.051 12.6 0.1 0.095 11.8 0.1 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KZN94162.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 KZN94162.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) NUT_C PF12882.2 KZN94163.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 NUT protein C terminal CHAP PF05257.11 KZN94163.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 CHAP domain zf-C2H2 PF00096.21 KZN94165.1 - 0.00012 22.2 9.8 0.036 14.4 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KZN94165.1 - 0.00036 20.6 8.2 0.041 14.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KZN94165.1 - 0.0012 19.0 0.3 0.0012 19.0 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain YlbD_coat PF14071.1 KZN94166.1 - 0.14 12.2 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Putative coat protein Fungal_trans_2 PF11951.3 KZN94167.1 - 3.6e-08 32.4 0.9 7.2e-08 31.4 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94167.1 - 1.7e-05 24.5 4.2 4.2e-05 23.3 2.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4662 PF15578.1 KZN94167.1 - 0.038 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF1454 PF07305.7 KZN94167.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Asp PF00026.18 KZN94168.1 - 1.4e-24 86.9 0.1 7.4e-24 84.5 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KZN94168.1 - 0.00035 20.5 0.0 0.00085 19.3 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CDC45 PF02724.9 KZN94169.1 - 6.3e-27 93.8 10.6 4.3e-26 91.1 7.3 2.6 1 1 0 1 1 1 1 CDC45-like protein AUX_IAA PF02309.11 KZN94169.1 - 0.085 12.5 2.2 0.11 12.2 1.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Tir_receptor_N PF07490.6 KZN94169.1 - 0.13 11.8 1.1 0.24 10.9 0.8 1.4 1 1 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus DNA_pol_viral_N PF00242.12 KZN94169.1 - 1.8 7.5 6.3 2.4 7.1 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain U79_P34 PF03064.11 KZN94169.1 - 3.1 7.2 9.9 4.5 6.7 6.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM176 PF14851.1 KZN94169.1 - 4.1 7.0 6.2 6.2 6.4 4.3 1.2 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.8 KZN94169.1 - 6.9 5.0 8.7 8.7 4.7 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mitofilin PF09731.4 KZN94171.1 - 0.83 8.2 6.6 0.05 12.2 0.5 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF3632 PF12311.3 KZN94174.1 - 1.6e-07 31.3 0.1 2.8e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.3 KZN94175.1 - 2.7e-25 88.3 19.7 3.3e-25 88.0 13.7 1.1 1 0 0 1 1 1 1 Antifungal protein DUF3632 PF12311.3 KZN94176.1 - 7.5e-36 123.6 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF1426 PF07234.6 KZN94178.1 - 0.2 11.3 1.0 18 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) Ank_2 PF12796.2 KZN94179.1 - 2.3e-59 197.7 14.7 9.5e-13 48.3 0.2 5.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KZN94179.1 - 4.3e-38 128.4 15.0 2.2e-08 34.0 0.0 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 KZN94179.1 - 7.7e-36 120.1 18.8 6.8e-07 28.7 0.0 10.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KZN94179.1 - 2.8e-34 116.8 14.4 5.2e-08 33.1 0.0 8.4 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94179.1 - 3.9e-30 100.8 14.4 0.0013 18.7 0.0 10.8 11 0 0 11 11 11 9 Ankyrin repeat F-box-like PF12937.2 KZN94179.1 - 0.0038 16.9 0.2 0.0074 15.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like PRKCSH-like PF12999.2 KZN94183.1 - 0.073 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like TFCD_C PF12612.3 KZN94184.1 - 0.0045 16.4 0.5 0.0057 16.0 0.4 1.1 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal zf-C4H2 PF10146.4 KZN94184.1 - 0.012 15.6 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein BRE1 PF08647.6 KZN94184.1 - 0.023 14.6 5.8 0.042 13.8 4.1 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase APG6 PF04111.7 KZN94184.1 - 0.46 9.4 6.3 0.54 9.2 4.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KZN94184.1 - 1 8.2 6.4 1.2 8.0 4.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Flagellar_rod PF05149.7 KZN94184.1 - 1.5 7.9 10.1 2.2 7.3 7.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein MAP7 PF05672.6 KZN94184.1 - 2.6 7.4 11.6 3.5 6.9 8.1 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SirB PF04247.7 KZN94186.1 - 0.043 13.5 3.5 0.17 11.5 1.1 2.5 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB FxsA PF04186.8 KZN94186.1 - 0.082 12.5 1.3 2 8.0 0.0 2.5 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Patatin PF01734.17 KZN94187.1 - 7.8e-22 78.2 1.7 9.9e-22 77.8 0.3 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KZN94187.1 - 0.0013 18.3 5.2 0.0045 16.6 3.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KZN94187.1 - 0.0026 17.7 8.7 0.0086 16.0 6.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KZN94187.1 - 0.0048 16.6 7.2 0.014 15.1 5.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KZN94187.1 - 0.14 12.0 9.0 0.39 10.5 6.2 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-JAB PF14464.1 KZN94189.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2706 PF10913.3 KZN94191.1 - 0.27 10.8 1.7 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) DUF3723 PF12520.3 KZN94192.1 - 2.3e-29 102.2 0.1 1.7e-27 96.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) DUF1129 PF06570.6 KZN94193.1 - 0.56 9.4 2.9 0.85 8.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YcfA PF07927.7 KZN94194.1 - 0.34 10.8 3.2 0.48 10.3 1.9 1.7 1 1 0 1 1 1 0 YcfA-like protein DUF4200 PF13863.1 KZN94196.1 - 0.27 11.1 9.0 0.38 10.6 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 KZN94196.1 - 1.6 7.7 6.9 1.8 7.5 4.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 KZN94196.1 - 2.4 8.2 8.0 3.9 7.5 5.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KZN94196.1 - 9.7 5.8 11.6 14 5.3 8.0 1.3 1 1 0 1 1 1 0 Mnd1 family CLASP_N PF12348.3 KZN94198.1 - 0.0039 16.5 1.3 0.2 11.0 0.0 3.1 1 1 3 4 4 4 1 CLASP N terminal GAF_3 PF13492.1 KZN94198.1 - 0.13 12.3 0.1 3 7.9 0.1 2.3 1 1 0 1 1 1 0 GAF domain DAP_epimerase PF01678.14 KZN94199.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase Mitofilin PF09731.4 KZN94200.1 - 0.028 13.1 1.3 0.051 12.2 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Scytalone_dh PF02982.9 KZN94202.1 - 1.2e-17 63.9 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KZN94202.1 - 2.7e-11 43.4 0.3 3.3e-11 43.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3129 PF11327.3 KZN94203.1 - 1.4e-41 142.3 6.2 1.9e-41 141.8 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) TPR_11 PF13414.1 KZN94206.1 - 5e-06 26.0 5.2 0.00031 20.3 1.0 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KZN94206.1 - 0.00059 19.3 2.1 0.074 12.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KZN94206.1 - 0.00071 20.1 5.0 0.00071 20.1 3.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KZN94206.1 - 0.042 13.7 7.7 0.31 11.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SpvB PF03534.8 KZN94206.1 - 0.17 10.8 0.1 17 4.2 0.0 2.4 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein MatE PF01554.13 KZN94207.1 - 8e-06 25.5 14.2 1.2e-05 25.0 0.5 3.3 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KZN94207.1 - 0.79 9.5 10.4 0.076 12.8 1.4 3.4 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DNA_pol_E_B PF04042.11 KZN94208.1 - 0.089 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Glyco_hydro_18 PF00704.23 KZN94209.1 - 2.4e-70 237.7 0.5 2.4e-70 237.7 0.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KZN94209.1 - 1.2e-08 34.8 20.6 1.5e-08 34.4 6.1 5.0 4 0 0 4 4 4 2 Chitin recognition protein Pectate_lyase_3 PF12708.2 KZN94210.1 - 5.4e-86 288.3 12.7 1.7e-68 231.1 4.6 3.4 3 0 0 3 3 3 2 Pectate lyase superfamily protein LysM PF01476.15 KZN94210.1 - 1.4e-10 40.9 0.5 0.001 18.9 0.0 3.6 3 0 0 3 3 3 3 LysM domain End_N_terminal PF12218.3 KZN94210.1 - 3.8e-06 26.2 2.5 0.043 13.2 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KZN94210.1 - 0.0055 16.4 2.5 0.0055 16.4 1.8 2.5 2 0 0 2 2 2 1 Right handed beta helix region Catalase-rel PF06628.7 KZN94212.1 - 4e-08 32.9 0.0 3.2e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive F-box-like PF12937.2 KZN94212.1 - 0.00013 21.5 0.4 0.00032 20.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KZN94212.1 - 0.0092 15.6 2.6 0.022 14.4 0.6 2.4 2 0 0 2 2 2 1 F-box domain Pkinase_Tyr PF07714.12 KZN94214.1 - 0.0012 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_8 PF00895.15 KZN94215.1 - 0.05 13.8 0.4 0.076 13.2 0.3 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 Ank_5 PF13857.1 KZN94215.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Zn_clus PF00172.13 KZN94217.1 - 1.9e-06 27.6 9.4 3.7e-06 26.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2146 PF10220.4 KZN94217.1 - 0.011 13.8 1.5 0.014 13.4 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Myb_DNA-bind_6 PF13921.1 KZN94218.1 - 8.2e-05 22.6 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN94218.1 - 0.04 13.9 0.1 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3435 PF11917.3 KZN94220.1 - 2.3e-148 494.3 3.1 2.3e-148 494.3 2.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) UPF0278 PF08745.6 KZN94220.1 - 0.052 12.7 1.2 0.11 11.6 0.8 1.5 1 0 0 1 1 1 0 UPF0278 family E1-E2_ATPase PF00122.15 KZN94221.1 - 3.9e-51 173.2 0.0 1.8e-50 171.1 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KZN94221.1 - 3.6e-38 132.1 0.6 6.8e-38 131.2 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN94221.1 - 2.8e-30 104.2 0.0 2.9e-08 33.7 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KZN94221.1 - 6.6e-16 59.0 0.0 1.5e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN94221.1 - 4.3e-05 23.2 0.3 0.00016 21.3 0.1 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Na_Ca_ex PF01699.19 KZN94223.1 - 4.4e-28 97.6 33.2 5.5e-14 51.9 6.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Chordopox_A13L PF05961.6 KZN94223.1 - 0.045 13.6 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein E1-E2_ATPase PF00122.15 KZN94224.1 - 2.4e-49 167.4 5.9 4.3e-49 166.6 4.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN94224.1 - 1.1e-23 84.8 0.0 1.8e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN94224.1 - 5.7e-15 55.9 0.0 1.2e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN94224.1 - 2.1e-05 24.5 0.1 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KZN94224.1 - 2.9e-05 23.7 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KZN94224.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LMWPc PF01451.16 KZN94225.1 - 2e-29 102.6 0.0 2.3e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF PF01758.11 KZN94226.1 - 1.1e-50 171.6 11.1 1.1e-50 171.6 7.7 2.5 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF1129 PF06570.6 KZN94226.1 - 0.52 9.5 4.7 0.18 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3671 PF12420.3 KZN94226.1 - 0.93 9.5 7.2 2.1 8.3 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function Cyclin PF08613.6 KZN94227.1 - 8.7e-27 94.3 0.1 1.3e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KZN94227.1 - 1.8e-05 24.2 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain FMN_red PF03358.10 KZN94228.1 - 3.6e-24 85.0 0.0 5.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase UBN2_2 PF14227.1 KZN94229.1 - 2.5e-14 52.8 0.6 5.7e-14 51.6 0.4 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KZN94229.1 - 7.3e-13 48.3 0.6 1.6e-12 47.2 0.4 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KZN94229.1 - 3.2e-05 23.5 0.8 0.13 11.7 0.3 2.8 1 1 0 2 2 2 2 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 KZN94229.1 - 0.00062 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1759 PF03564.10 KZN94229.1 - 0.015 15.0 0.5 0.056 13.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) RCC1_2 PF13540.1 KZN94231.1 - 0.6 9.8 3.2 11 5.7 0.2 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat HeLo PF14479.1 KZN94232.1 - 9.5e-63 211.7 0.0 1.4e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KZN94232.1 - 0.038 13.0 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase 5_nucleotid PF05761.9 KZN94233.1 - 0.22 9.9 6.3 0.3 9.5 4.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family Ndc1_Nup PF09531.5 KZN94233.1 - 0.92 7.8 6.3 1 7.6 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NUDIX PF00293.23 KZN94234.1 - 2.5e-06 27.1 0.2 3.9e-06 26.5 0.1 1.3 1 1 0 1 1 1 1 NUDIX domain FNIP PF05725.7 KZN94235.1 - 0.00048 20.0 0.4 15 5.6 0.0 3.5 3 0 0 3 3 3 3 FNIP Repeat APH PF01636.18 KZN94236.1 - 2.8e-10 40.3 0.0 4.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Endosulfine PF04667.12 KZN94237.1 - 4.7e-07 29.6 0.1 1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Kdo PF06293.9 KZN94238.1 - 0.00042 19.4 0.1 0.00089 18.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN94238.1 - 0.001 18.8 5.3 0.0054 16.4 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 KZN94238.1 - 0.13 11.3 0.1 0.49 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain AAA PF00004.24 KZN94239.1 - 9.4e-18 64.6 0.1 3.3e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KZN94239.1 - 0.0025 17.8 0.7 0.16 11.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KZN94239.1 - 0.0028 18.4 0.3 0.015 16.0 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KZN94239.1 - 0.032 13.9 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KZN94239.1 - 0.09 13.0 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KZN94239.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KZN94239.1 - 0.13 12.3 3.3 3.1 7.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain Rnk_N PF14760.1 KZN94239.1 - 0.41 10.7 3.1 23 5.1 0.0 3.4 3 0 0 3 3 3 0 Rnk N-terminus Myb_DNA-bind_6 PF13921.1 KZN94242.1 - 0.00053 20.0 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KZN94242.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KZN94242.1 - 0.098 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 NmrA PF05368.8 KZN94243.1 - 1.2e-13 50.8 0.1 2e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN94243.1 - 7.8e-10 39.0 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KZN94243.1 - 0.0039 16.8 0.6 0.24 11.0 0.1 2.6 2 1 1 3 3 3 1 KR domain Semialdhyde_dh PF01118.19 KZN94243.1 - 0.081 13.2 0.1 0.21 11.8 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Apc4 PF12896.2 KZN94246.1 - 1.1e-67 227.4 1.0 1.5e-67 226.9 0.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 KZN94246.1 - 6.2e-20 70.4 0.0 2.1e-18 65.5 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KZN94246.1 - 0.00081 19.1 0.0 0.018 14.9 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat IKI3 PF04762.7 KZN94246.1 - 0.014 13.2 0.0 3 5.5 0.0 2.1 2 0 0 2 2 2 0 IKI3 family VWA PF00092.23 KZN94248.1 - 1.7e-06 27.8 0.5 0.00048 19.8 0.1 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KZN94248.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans_2 PF11951.3 KZN94249.1 - 6.2e-10 38.2 5.2 2.5e-08 32.9 3.6 2.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transgly_assoc PF04226.8 KZN94249.1 - 0.0091 16.0 0.0 0.055 13.5 0.0 2.3 3 0 0 3 3 3 1 Transglycosylase associated protein GFA PF04828.9 KZN94250.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KZN94250.1 - 0.066 12.4 0.3 0.17 11.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KZN94250.1 - 0.066 12.7 0.5 0.16 11.5 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HLH PF00010.21 KZN94251.1 - 3.7e-08 32.9 0.0 5.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Maf PF02545.9 KZN94252.1 - 1.5e-46 157.9 0.0 2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein CybS PF05328.7 KZN94253.1 - 3.2e-49 165.9 0.0 4.3e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 CybS ADH_zinc_N PF00107.21 KZN94254.1 - 6e-23 80.8 0.0 9.4e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KZN94254.1 - 1.1e-06 29.5 0.0 3.2e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KZN94254.1 - 0.0037 17.2 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Pyr_redox_2 PF07992.9 KZN94255.1 - 9.8e-15 54.9 3.1 1.2e-12 48.0 1.5 3.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KZN94255.1 - 5e-13 49.2 0.5 1.8e-10 41.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN94255.1 - 3.8e-05 22.7 1.2 0.00069 18.6 0.0 2.8 3 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KZN94255.1 - 0.0003 20.8 2.9 0.48 10.4 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KZN94255.1 - 0.00031 19.7 1.9 0.52 9.1 0.0 3.7 3 1 0 4 4 4 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KZN94255.1 - 0.0014 17.7 0.0 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KZN94255.1 - 0.049 12.7 1.7 1.8 7.6 0.0 2.6 2 1 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 KZN94255.1 - 0.094 11.6 0.3 1.7 7.5 0.0 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DEAD PF00270.24 KZN94256.1 - 6.2e-41 139.7 0.1 1e-40 139.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KZN94256.1 - 6e-19 67.6 0.7 1.4e-18 66.4 0.5 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN94256.1 - 0.0034 17.2 0.0 0.0081 16.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KZN94256.1 - 0.0095 15.2 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain Adenylsucc_synt PF00709.16 KZN94257.1 - 1.8e-153 511.2 0.0 2e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Tub_2 PF04525.7 KZN94258.1 - 4.4e-25 88.1 0.0 5e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 DnaJ PF00226.26 KZN94259.1 - 1.3e-20 72.8 1.1 2.8e-20 71.8 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KZN94260.1 - 1.1e-27 96.5 0.0 2e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94260.1 - 8.5e-09 35.1 11.3 1.3e-08 34.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KZN94261.1 - 2.5e-41 141.5 9.3 5.9e-30 104.1 0.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN94261.1 - 5.9e-11 41.6 6.4 5.9e-11 41.6 4.4 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KZN94261.1 - 2.8e-05 22.6 3.5 2.8e-05 22.6 2.4 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein BT1 PF03092.11 KZN94261.1 - 0.0056 15.4 0.7 0.0056 15.4 0.5 1.9 1 1 0 2 2 2 1 BT1 family MFS_3 PF05977.8 KZN94261.1 - 0.26 9.3 10.4 0.05 11.7 2.7 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector GTP1_OBG PF01018.17 KZN94262.1 - 1.7e-39 135.0 2.6 1.4e-29 102.7 1.6 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KZN94262.1 - 1.9e-20 72.9 0.0 3.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN94262.1 - 1.7e-08 33.9 0.1 6.6e-08 31.9 0.0 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 KZN94262.1 - 0.0018 17.1 0.0 0.4 9.4 0.0 2.2 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KZN94262.1 - 0.0029 17.0 0.0 0.43 9.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KZN94262.1 - 0.004 17.4 0.6 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 KZN94262.1 - 0.023 15.1 0.0 0.065 13.7 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KZN94262.1 - 0.041 13.7 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Cupin_8 PF13621.1 KZN94263.1 - 8.6e-32 110.6 0.0 2.1e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KZN94263.1 - 3.2e-05 23.3 0.1 0.0075 15.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KZN94263.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF1537 PF07005.6 KZN94264.1 - 1.3e-22 80.6 7.4 2.2e-22 79.8 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Glu_syn_central PF04898.9 KZN94264.1 - 0.12 11.5 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Glutamate synthase central domain CDC45 PF02724.9 KZN94265.1 - 2e-243 809.0 0.0 4.7e-243 807.8 0.0 2.0 1 1 0 1 1 1 1 CDC45-like protein Tir_receptor_N PF07490.6 KZN94265.1 - 0.021 14.4 1.1 0.054 13.1 0.7 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Nop14 PF04147.7 KZN94265.1 - 0.06 11.2 23.2 0.1 10.5 6.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2360 PF10152.4 KZN94265.1 - 0.26 11.5 6.2 0.31 11.3 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF2201_N PF13203.1 KZN94265.1 - 0.37 9.9 18.5 0.8 8.8 3.2 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain HHV6-IE PF03753.8 KZN94265.1 - 1.8 5.9 13.7 0.0078 13.7 0.3 2.0 2 0 0 2 2 2 0 Human herpesvirus 6 immediate early protein MIP-T3 PF10243.4 KZN94265.1 - 2.1 6.6 30.6 0.28 9.5 0.7 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF3513 PF12026.3 KZN94265.1 - 2.6 7.5 6.4 5.4 6.5 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FLO_LFY PF01698.11 KZN94265.1 - 6.2 5.5 14.3 0.24 10.2 4.9 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein FAM60A PF15396.1 KZN94265.1 - 6.7 6.4 14.6 0.057 13.1 2.9 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Peptidase_C13 PF01650.13 KZN94266.1 - 5.9e-40 137.1 0.1 8.2e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF1014 PF06244.7 KZN94267.1 - 1.1e-24 86.9 16.7 4.2e-24 85.1 11.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) WD40 PF00400.27 KZN94268.1 - 1.7e-27 94.2 21.9 1.2e-09 37.6 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 KZN94270.1 - 8.3e-36 123.6 0.2 1.1e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KZN94270.1 - 0.0019 18.0 5.7 0.0019 18.0 4.0 1.7 2 0 0 2 2 2 1 GRF zinc finger CUE PF02845.11 KZN94270.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 CUE domain DGF-1_C PF11040.3 KZN94270.1 - 0.082 12.7 1.4 0.53 10.1 0.1 2.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus GMC_oxred_N PF00732.14 KZN94271.1 - 1.7e-63 214.5 0.0 2.5e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KZN94271.1 - 2.6e-36 125.0 0.1 4.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KZN94271.1 - 4.1e-06 25.9 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KZN94271.1 - 8.1e-05 21.6 2.5 0.002 17.0 1.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KZN94271.1 - 0.0064 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KZN94271.1 - 0.0088 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KZN94271.1 - 0.045 12.2 0.0 0.11 11.0 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KZN94271.1 - 0.054 12.5 0.2 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KZN94271.1 - 0.11 11.3 0.6 9.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A UQ_con PF00179.21 KZN94272.1 - 2.2e-10 40.0 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN94272.1 - 0.15 11.9 0.1 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 RWD domain Asp_Glu_race PF01177.17 KZN94273.1 - 3.3e-30 105.6 1.4 3.6e-30 105.5 0.9 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fungal_trans_2 PF11951.3 KZN94275.1 - 4.1e-31 107.9 8.2 8.8e-31 106.8 5.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KZN94276.1 - 9.1e-81 271.3 0.0 1.4e-80 270.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KZN94276.1 - 3.3e-57 193.2 0.0 5.3e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KZN94276.1 - 2.8e-11 43.4 0.1 5.7e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KZN94276.1 - 5.4e-08 31.8 0.0 2.4e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN94276.1 - 9.3e-08 31.7 0.0 8.7e-07 28.6 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN94276.1 - 0.022 14.7 0.0 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 NADH(P)-binding NmrA PF05368.8 KZN94277.1 - 4.2e-35 121.0 0.0 7.9e-35 120.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN94277.1 - 4.7e-14 52.8 0.0 7.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KZN94277.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KZN94277.1 - 0.097 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 KZN94277.1 - 0.11 12.9 0.1 0.32 11.4 0.1 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KZN94277.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 KZN94278.1 - 1.3e-68 231.6 0.0 1.6e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_3 PF13469.1 KZN94279.1 - 1.9e-05 25.6 0.4 3e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 Sulfotransferase family Methyltransf_25 PF13649.1 KZN94280.1 - 1.3e-10 41.5 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN94280.1 - 2.5e-09 37.4 0.0 5.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN94280.1 - 5.6e-08 32.5 0.0 7.4e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN94280.1 - 1.1e-06 29.1 0.0 2.5e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN94280.1 - 2.6e-06 27.8 0.0 5.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN94280.1 - 2.7e-05 23.9 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN94280.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KZN94280.1 - 0.0016 18.5 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 KZN94281.1 - 1.4e-21 76.6 27.4 8e-13 47.8 2.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KZN94281.1 - 4.7e-06 25.2 12.7 0.0024 16.3 1.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KZN94281.1 - 0.027 14.2 0.4 0.12 12.1 0.3 2.2 1 0 0 1 1 1 0 MFS_1 like family DUF3043 PF11241.3 KZN94281.1 - 0.094 12.2 0.1 0.52 9.8 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) DUF202 PF02656.10 KZN94281.1 - 2.7 8.2 14.6 0.66 10.2 0.6 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 KZN94282.1 - 2.4e-66 224.2 24.4 2.7e-66 224.0 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN94282.1 - 1.6e-08 33.6 33.1 1.6e-08 33.6 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KZN94282.1 - 0.00015 20.2 3.7 0.00015 20.2 2.6 3.7 3 2 1 4 4 4 3 MFS/sugar transport protein Ribonuc_L-PSP PF01042.16 KZN94283.1 - 1.7e-35 121.4 0.0 1.8e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_S13 PF02113.10 KZN94283.1 - 0.09 11.2 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pkinase PF00069.20 KZN94284.1 - 1.8e-28 99.3 0.0 3.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN94284.1 - 2.8e-12 46.2 0.0 9.5e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_trans_2 PF11951.3 KZN94284.1 - 1.6e-10 40.1 1.8 2.9e-10 39.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94284.1 - 3e-08 33.4 11.1 3e-08 33.4 7.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_ser-thr_kin PF05445.6 KZN94284.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KZN94284.1 - 0.057 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KZN94284.1 - 0.062 12.2 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like CN_hydrolase PF00795.17 KZN94285.1 - 4.1e-31 107.7 0.0 5.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PALP PF00291.20 KZN94286.1 - 7.5e-67 225.7 0.1 9.6e-67 225.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme D-ser_dehydrat PF14031.1 KZN94287.1 - 2.1e-20 72.6 0.0 7.4e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KZN94287.1 - 6.3e-13 48.7 0.1 9.1e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Zn_clus PF00172.13 KZN94288.1 - 4.1e-08 32.9 10.8 1.1e-07 31.5 7.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KZN94288.1 - 1.1e-05 24.2 0.1 1.7e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2524 PF10732.4 KZN94288.1 - 0.023 14.7 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Cutinase PF01083.17 KZN94289.1 - 1.6e-27 96.3 0.6 2.5e-27 95.7 0.4 1.3 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 KZN94289.1 - 7.2e-05 23.1 0.0 0.00016 21.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 KZN94289.1 - 0.00038 20.1 0.0 0.00047 19.7 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.6 KZN94289.1 - 0.00072 19.0 0.1 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF726 PF05277.7 KZN94289.1 - 0.0042 16.0 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KZN94289.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3130 PF11328.3 KZN94289.1 - 0.026 14.5 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 VirJ PF06057.6 KZN94289.1 - 0.097 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.11 KZN94290.1 - 4.3e-10 38.8 45.1 3.1e-08 32.7 13.8 3.2 1 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN94290.1 - 7.1e-08 31.4 12.3 7.1e-08 31.4 8.5 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 KZN94290.1 - 0.14 11.9 5.9 0.14 11.9 0.3 3.0 3 0 0 3 3 3 0 MFS_1 like family Glyco_hydro_3_C PF01915.17 KZN94291.1 - 6.6e-19 68.3 0.0 2.3e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.19 KZN94292.1 - 8.9e-95 317.8 27.7 1e-94 317.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN94292.1 - 1.2e-33 116.3 46.4 1.3e-28 99.8 17.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KZN94292.1 - 7.1e-07 27.8 1.4 7.1e-07 27.8 0.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Homeobox_KN PF05920.6 KZN94293.1 - 1.9e-15 56.2 2.1 4.2e-15 55.1 1.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KZN94293.1 - 4.5e-08 32.5 0.2 9.9e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 KZN94293.1 - 1.1e-05 25.5 12.3 0.023 15.0 0.8 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 KZN94293.1 - 0.00034 20.3 0.2 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 KZN94293.1 - 0.0008 19.5 18.9 0.013 15.8 0.8 4.6 4 1 0 4 4 4 2 C2H2-type zinc finger Cu-oxidase_3 PF07732.10 KZN94294.1 - 4.3e-35 120.0 2.1 3.9e-34 116.8 0.0 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KZN94294.1 - 1.3e-27 96.0 3.6 1.7e-22 79.4 0.7 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 KZN94294.1 - 2.3e-14 53.6 0.0 7.9e-13 48.5 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase Thioredoxin PF00085.15 KZN94295.1 - 3.6e-28 97.2 0.1 4.2e-28 97.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KZN94295.1 - 2e-06 27.7 0.2 4.7e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KZN94295.1 - 3.5e-06 27.1 1.4 3.2e-05 24.1 1.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Phosducin PF02114.11 KZN94295.1 - 6.2e-05 21.8 0.0 6.9e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.1 KZN94295.1 - 0.00016 21.6 0.1 0.00024 21.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KZN94295.1 - 0.00052 19.7 0.2 0.001 18.7 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 KZN94295.1 - 0.026 14.0 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 KZN94295.1 - 0.06 12.8 0.3 0.2 11.1 0.1 1.6 1 1 1 2 2 2 0 Redoxin Thioredoxin_4 PF13462.1 KZN94295.1 - 0.12 12.3 0.6 3.2 7.7 0.3 2.0 1 1 1 2 2 2 0 Thioredoxin RRM_1 PF00076.17 KZN94296.1 - 4.7e-24 83.7 0.1 6.3e-24 83.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN94296.1 - 5.5e-18 64.7 0.0 7.2e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN94296.1 - 1.2e-10 41.0 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KZN94296.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 Limkain b1 Fungal_trans PF04082.13 KZN94297.1 - 1.8e-22 79.5 0.1 5.8e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94297.1 - 3.8e-07 29.9 7.0 6.5e-07 29.1 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.13 KZN94298.1 - 4.6e-18 65.5 0.0 6.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KZN94298.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Abhydrolase_1 PF00561.15 KZN94299.1 - 1.4e-12 47.6 0.0 5.8e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KZN94299.1 - 7.6e-12 45.6 0.0 1e-11 45.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KZN94299.1 - 0.0069 15.6 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KZN94299.1 - 0.035 13.8 0.1 0.2 11.3 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.12 KZN94300.1 - 9.2e-105 349.0 0.0 1.3e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KZN94300.1 - 8.3e-50 168.3 0.0 1.5e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KZN94300.1 - 1e-09 38.5 0.0 3.1e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 KZN94300.1 - 0.097 10.1 0.0 0.16 9.5 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Prenyltrans PF00432.16 KZN94301.1 - 1.1e-29 101.6 3.3 1.5e-09 37.2 0.1 4.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KZN94301.1 - 2.2e-22 79.1 0.0 8e-13 48.3 0.0 5.3 3 2 1 5 5 5 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 KZN94301.1 - 4.1e-22 78.7 0.5 1.5e-13 51.1 0.0 4.3 3 2 0 4 4 4 3 Prenyltransferase-like Pec_lyase PF09492.5 KZN94301.1 - 6.5e-07 28.7 0.3 0.049 12.8 0.0 4.3 4 1 0 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 KZN94301.1 - 0.0053 16.0 0.0 0.03 13.5 0.0 2.2 1 1 1 2 2 2 1 A-macroglobulin complement component Mago-bind PF09282.5 KZN94301.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Mago binding Abhydrolase_6 PF12697.2 KZN94302.1 - 2.7e-27 96.1 0.1 3.6e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KZN94302.1 - 5e-07 29.5 0.0 6.9e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KZN94302.1 - 8.2e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KZN94302.1 - 0.058 11.6 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Fungal_trans PF04082.13 KZN94304.1 - 7.2e-24 84.0 0.1 1.3e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94304.1 - 3.6e-07 29.9 12.1 9.4e-07 28.6 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 KZN94305.1 - 1e-31 110.0 2.1 1.5e-31 109.5 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KZN94305.1 - 7.8e-16 57.3 0.7 1.3e-15 56.6 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KZN94305.1 - 2.6e-08 34.2 1.1 2.6e-08 34.2 0.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KZN94305.1 - 0.0035 17.9 0.0 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Pyr_redox_3 PF13738.1 KZN94306.1 - 1.8e-22 80.4 0.0 2.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KZN94306.1 - 4.1e-13 48.3 0.1 5e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KZN94306.1 - 1.1e-11 44.5 0.0 3.1e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KZN94306.1 - 5.3e-06 25.5 0.0 0.00041 19.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KZN94306.1 - 4.2e-05 23.3 0.0 0.00033 20.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KZN94306.1 - 0.00026 20.0 0.0 0.0074 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KZN94306.1 - 0.006 15.7 0.0 0.29 10.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family AMP-binding PF00501.23 KZN94307.1 - 7.8e-75 251.8 0.0 9.8e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN94307.1 - 1.6e-11 44.9 0.1 7.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KZN94308.1 - 0.0005 19.5 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KZN94308.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KZN94308.1 - 0.024 13.5 0.0 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein COesterase PF00135.23 KZN94309.1 - 4.2e-07 29.0 0.0 4.8e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF3237 PF11578.3 KZN94310.1 - 4.1e-24 84.5 0.0 5.1e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) KH_1 PF00013.24 KZN94310.1 - 0.093 12.3 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 KH domain ADH_zinc_N PF00107.21 KZN94311.1 - 4e-16 58.7 0.3 5.6e-16 58.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EGF_alliinase PF04863.8 KZN94311.1 - 0.018 15.0 0.5 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Alliinase EGF-like domain Mito_carr PF00153.22 KZN94312.1 - 3.3e-48 161.3 8.8 4.8e-18 64.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3632 PF12311.3 KZN94313.1 - 3e-52 177.0 0.5 3.7e-52 176.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Alpha-amylase PF00128.19 KZN94314.1 - 5.2e-22 78.6 7.2 3.3e-21 76.0 2.0 2.5 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KZN94314.1 - 0.037 11.7 0.1 4.7 4.8 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 MFS_1 PF07690.11 KZN94315.1 - 5.9e-37 127.1 35.9 5.9e-37 127.1 24.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN94315.1 - 1.8e-15 56.5 7.7 1.8e-15 56.5 5.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KZN94315.1 - 8.1e-06 24.3 2.3 8.1e-06 24.3 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Colicin_im PF03857.8 KZN94315.1 - 0.17 11.6 4.1 3.7 7.3 0.6 2.5 2 0 0 2 2 2 0 Colicin immunity protein DUF1434 PF07254.7 KZN94315.1 - 4.8 6.9 6.8 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1434) DUF3445 PF11927.3 KZN94316.1 - 1.3e-70 237.6 0.0 1.6e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.1 KZN94317.1 - 3.1e-45 154.9 0.2 4.8e-45 154.2 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KZN94317.1 - 1.3e-23 83.0 0.0 4.5e-12 45.7 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.1 KZN94317.1 - 0.13 11.8 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Caveolin PF01146.12 KZN94318.1 - 0.15 11.6 0.5 0.21 11.1 0.2 1.5 1 1 0 1 1 1 0 Caveolin DUF1469 PF07332.6 KZN94318.1 - 0.74 9.5 6.1 5.4 6.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Amidase PF01425.16 KZN94319.1 - 9.9e-38 130.1 0.7 3.3e-34 118.5 0.4 2.1 2 0 0 2 2 2 2 Amidase Fungal_trans PF04082.13 KZN94321.1 - 2.2e-24 85.7 0.0 3.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94321.1 - 1.3e-05 24.9 14.8 3e-05 23.8 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.7 KZN94323.1 - 7.5e-91 303.8 0.0 9.5e-91 303.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KZN94323.1 - 2.5e-05 24.0 0.0 8.4e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN94323.1 - 0.0034 17.8 0.0 0.017 15.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN94323.1 - 0.0054 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HSP70 PF00012.15 KZN94324.1 - 4.2e-10 38.1 0.3 1.3e-08 33.3 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KZN94324.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 KZN94324.1 - 0.05 12.1 0.1 0.25 9.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Prefoldin_2 PF01920.15 KZN94325.1 - 6e-24 83.8 4.2 8e-24 83.4 2.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.5 KZN94325.1 - 0.028 14.5 3.5 2 8.5 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family eIF-4B PF06273.6 KZN94325.1 - 0.037 12.7 2.8 0.044 12.5 1.9 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B AAA_23 PF13476.1 KZN94325.1 - 0.081 13.2 3.4 0.098 12.9 2.3 1.1 1 0 0 1 1 1 0 AAA domain FliD_C PF07195.7 KZN94325.1 - 0.097 11.9 1.6 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TBCA PF02970.11 KZN94325.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A DivIC PF04977.10 KZN94325.1 - 0.82 9.1 10.6 6.1 6.3 4.0 2.2 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.1 KZN94325.1 - 1.3 8.1 9.7 4.5 6.4 4.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.6 KZN94325.1 - 1.5 8.5 6.4 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KfrA_N PF11740.3 KZN94325.1 - 1.8 9.0 5.6 5.6 7.4 0.0 2.3 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4164 PF13747.1 KZN94325.1 - 3.4 7.8 10.9 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ATG27 PF09451.5 KZN94326.1 - 3.1e-81 272.5 0.0 3.8e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KZN94326.1 - 9.1e-06 25.5 0.2 0.005 16.6 0.1 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat PD40 PF07676.7 KZN94327.1 - 4.2e-45 150.7 33.0 6.1e-08 32.1 2.1 9.8 10 0 0 10 10 10 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KZN94327.1 - 4.4e-11 41.9 3.5 0.24 9.9 0.0 6.8 4 2 1 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_2 PF07724.9 KZN94329.1 - 1.3e-45 155.4 0.0 2.7e-44 151.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KZN94329.1 - 2.2e-27 95.8 0.0 6.1e-15 55.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KZN94329.1 - 9.2e-24 83.1 0.4 2.7e-23 81.6 0.3 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KZN94329.1 - 2.6e-15 56.3 0.0 2.1e-09 37.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KZN94329.1 - 2.5e-14 53.6 13.4 6.5e-06 26.2 0.0 6.3 3 2 3 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 KZN94329.1 - 1.1e-13 51.5 0.1 5.4e-05 23.3 0.0 4.2 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KZN94329.1 - 1.3e-08 35.6 2.4 0.0099 16.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KZN94329.1 - 1.7e-08 34.0 0.0 5.5e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KZN94329.1 - 7.4e-08 32.0 0.0 0.024 14.0 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 KZN94329.1 - 1e-07 32.2 0.4 0.009 16.3 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_19 PF13245.1 KZN94329.1 - 2.9e-07 30.1 0.0 0.018 14.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Arch_ATPase PF01637.13 KZN94329.1 - 3.3e-07 30.2 0.4 0.01 15.5 0.1 4.4 3 1 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 KZN94329.1 - 5.6e-07 29.4 0.0 0.048 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KZN94329.1 - 1.4e-05 25.0 0.2 0.3 11.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 KZN94329.1 - 1.7e-05 24.0 0.0 0.14 11.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KZN94329.1 - 5.8e-05 23.2 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KZN94329.1 - 7.5e-05 22.6 0.0 0.19 11.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KZN94329.1 - 0.00013 20.9 0.4 0.0061 15.5 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 KZN94329.1 - 0.00014 22.1 1.4 0.47 10.7 0.0 3.7 4 0 0 4 4 3 1 ABC transporter MobB PF03205.9 KZN94329.1 - 0.00016 21.4 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 KZN94329.1 - 0.0002 21.0 0.0 0.72 9.4 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KZN94329.1 - 0.00035 20.1 3.4 0.19 11.1 0.0 4.7 4 2 0 5 5 5 1 AAA-like domain AAA_29 PF13555.1 KZN94329.1 - 0.00039 19.8 0.0 0.28 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KZN94329.1 - 0.0004 19.8 0.0 2 7.7 0.0 3.5 2 1 1 3 3 3 2 AAA domain DUF258 PF03193.11 KZN94329.1 - 0.00094 18.4 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 KZN94329.1 - 0.0031 17.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KZN94329.1 - 0.0032 17.2 0.0 0.21 11.3 0.0 3.1 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 KZN94329.1 - 0.0054 16.4 0.0 0.44 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.10 KZN94329.1 - 0.0088 15.8 0.0 3.1 7.6 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 KZN94329.1 - 0.016 14.6 0.1 6.4 6.1 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 KZN94329.1 - 0.018 15.0 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KZN94329.1 - 0.049 13.2 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KZN94329.1 - 0.058 13.3 0.1 1.2 9.1 0.0 3.2 3 1 0 3 3 2 0 50S ribosome-binding GTPase Torsin PF06309.6 KZN94329.1 - 0.069 13.0 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_23 PF13476.1 KZN94329.1 - 2.6 8.3 0.0 2.6 8.3 0.0 4.0 3 2 1 4 4 3 0 AAA domain Viral_P18 PF04521.8 KZN94329.1 - 4.7 6.6 7.4 11 5.4 0.9 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ank_2 PF12796.2 KZN94330.1 - 4.5e-28 97.4 1.6 1.3e-09 38.2 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KZN94330.1 - 7.4e-21 72.8 3.8 0.0017 18.0 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat HET PF06985.6 KZN94330.1 - 1.1e-17 64.5 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 KZN94330.1 - 3.7e-17 62.3 0.9 5.1e-07 30.0 0.0 4.8 4 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KZN94330.1 - 5.1e-14 50.9 1.1 0.0062 16.6 0.0 6.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 KZN94330.1 - 3.4e-13 49.3 3.7 0.0022 18.1 0.0 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF2721 PF11026.3 KZN94331.1 - 1.3 8.6 6.8 11 5.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SHP PF03579.8 KZN94331.1 - 3.8 6.9 7.9 0.35 10.2 1.6 2.1 2 0 0 2 2 2 0 Small hydrophobic protein AA_permease_2 PF13520.1 KZN94332.1 - 8.9e-42 143.1 50.9 1.1e-41 142.7 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KZN94332.1 - 2.4e-15 55.8 42.9 4e-15 55.1 29.8 1.3 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.18 KZN94333.1 - 9.5e-63 211.7 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KZN94333.1 - 6.2e-12 45.2 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KZN94333.1 - 9.5e-05 22.2 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KZN94333.1 - 0.0011 17.8 0.0 0.0054 15.5 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 EBP PF05241.7 KZN94335.1 - 2.5e-69 232.1 11.0 3.1e-69 231.8 7.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF996 PF06195.8 KZN94335.1 - 0.57 10.1 3.7 0.21 11.6 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF996) adh_short_C2 PF13561.1 KZN94336.1 - 1.9e-28 99.8 0.0 2e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN94336.1 - 2.9e-21 76.0 0.7 1.5e-20 73.7 0.0 2.2 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 KZN94336.1 - 9.1e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1929 PF09118.6 KZN94338.1 - 7.5e-14 51.6 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DUF2347 PF09804.4 KZN94339.1 - 1.2e-101 339.7 0.0 1.6e-101 339.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KZN94339.1 - 7.2e-60 202.0 0.1 1e-59 201.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 KZN94339.1 - 0.00061 18.3 0.0 1.1 7.6 0.0 2.4 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 KZN94339.1 - 0.0031 17.2 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Thg1C PF14413.1 KZN94340.1 - 0.27 10.9 1.4 0.65 9.6 1.0 1.6 1 0 0 1 1 1 0 Thg1 C terminal domain ATG16 PF08614.6 KZN94340.1 - 0.35 10.6 23.4 2.2 8.0 14.0 3.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF342 PF03961.8 KZN94340.1 - 0.93 7.8 6.6 1.3 7.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 KZN94340.1 - 6.2 5.6 15.6 14 4.5 10.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 KZN94340.1 - 7.5 6.3 10.0 4.5 7.0 2.5 2.3 1 1 1 2 2 2 0 Laminin Domain II Tubulin_3 PF14881.1 KZN94341.1 - 1.7e-86 288.3 0.3 3.7e-86 287.2 0.2 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KZN94341.1 - 4.4e-44 149.2 0.6 2.5e-43 146.8 0.1 2.5 2 1 1 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KZN94341.1 - 8.9e-07 28.9 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain HSP70 PF00012.15 KZN94343.1 - 1.8e-65 221.0 3.4 1.8e-65 221.0 2.4 2.6 2 1 0 2 2 2 1 Hsp70 protein TruD PF01142.13 KZN94345.1 - 1.6e-54 185.0 0.1 3.4e-50 170.7 0.0 4.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ins145_P3_rec PF08709.6 KZN94345.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor SKG6 PF08693.5 KZN94346.1 - 1.7e-06 27.1 5.2 2.9e-05 23.2 0.1 3.2 3 0 0 3 3 3 2 Transmembrane alpha-helix domain DUF4448 PF14610.1 KZN94346.1 - 8.5e-06 25.3 0.1 2.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KZN94346.1 - 0.0001 22.0 0.2 0.00025 20.7 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.7 KZN94346.1 - 0.0072 16.2 2.4 0.0072 16.2 1.7 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1180) DUF3188 PF11384.3 KZN94346.1 - 0.0077 15.7 0.3 0.022 14.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) Mid2 PF04478.7 KZN94346.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HSP20 PF00011.16 KZN94347.1 - 1e-18 67.0 0.1 7.9e-18 64.1 0.1 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Glyco_hydro_43 PF04616.9 KZN94349.1 - 1.7e-40 138.8 5.2 2e-40 138.7 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Na_H_Exchanger PF00999.16 KZN94350.1 - 4.2e-41 140.7 22.6 6.9e-41 140.0 15.6 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Abhydrolase_5 PF12695.2 KZN94351.1 - 5.1e-06 26.3 0.0 9.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KZN94351.1 - 4.1e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PRTP PF01366.13 KZN94351.1 - 0.00027 19.0 0.2 0.00036 18.6 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus processing and transport protein UPF0227 PF05728.7 KZN94351.1 - 0.001 18.8 0.1 0.0026 17.5 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KZN94351.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KZN94351.1 - 0.0043 17.2 0.4 0.0083 16.3 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 KZN94351.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KZN94351.1 - 0.035 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KZN94351.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CagX PF03524.10 KZN94351.1 - 0.084 12.1 1.7 0.13 11.5 1.2 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Lamp PF01299.12 KZN94351.1 - 0.11 11.5 5.3 0.18 10.8 3.7 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Colicin-DNase PF12639.2 KZN94352.1 - 0.14 12.3 1.9 0.49 10.6 0.6 2.4 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin MT0933_antitox PF14013.1 KZN94352.1 - 2.3 8.4 12.7 59 3.8 1.3 4.7 2 1 1 4 4 4 0 MT0933-like antitoxin protein ELO PF01151.13 KZN94353.1 - 3.1e-86 288.7 7.9 3.8e-86 288.4 5.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_35 PF01301.14 KZN94354.1 - 5e-72 242.9 0.9 1.2e-71 241.6 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KZN94354.1 - 2.3e-66 222.6 0.5 4.2e-66 221.7 0.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KZN94354.1 - 7.9e-50 167.7 10.3 6.1e-26 90.8 1.6 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KZN94354.1 - 3.3e-30 103.2 0.3 7.9e-29 98.8 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 KZN94354.1 - 3.1e-06 26.6 0.5 5.7e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans_2 PF11951.3 KZN94355.1 - 4.1e-15 55.2 0.5 8.5e-07 27.8 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain COesterase PF00135.23 KZN94356.1 - 5.5e-72 243.1 0.0 7.3e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KZN94356.1 - 1.1e-05 25.0 1.7 0.061 12.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KZN94356.1 - 0.0037 16.5 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KZN94356.1 - 0.014 14.8 0.1 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.2 KZN94356.1 - 0.019 14.7 0.2 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3237 PF11578.3 KZN94358.1 - 4.9e-13 48.6 0.1 1.2e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.11 KZN94359.1 - 3.5e-30 104.9 28.9 4.6e-30 104.5 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Hexapep PF00132.19 KZN94361.1 - 5.7e-08 31.9 5.2 0.00083 18.7 0.6 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KZN94361.1 - 7.9e-05 22.7 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KZN94361.1 - 0.0084 15.6 4.0 0.4 10.2 0.7 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.3 KZN94363.1 - 1.1e-52 178.0 0.2 1.1e-52 178.0 0.1 4.2 3 1 0 3 3 3 1 Spt20 family zf-C2H2 PF00096.21 KZN94364.1 - 8.4e-08 32.1 12.4 0.00072 19.7 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KZN94364.1 - 1.4e-05 25.1 4.3 1.4e-05 25.1 3.0 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KZN94364.1 - 6.5e-05 22.9 10.6 0.0035 17.5 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger MFS_1 PF07690.11 KZN94365.1 - 4.8e-30 104.4 27.2 1.4e-17 63.4 4.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KZN94365.1 - 1.1e-07 30.3 0.6 1.1e-07 30.3 0.4 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family IncA PF04156.9 KZN94365.1 - 0.093 12.3 0.2 0.093 12.3 0.1 3.0 3 0 0 3 3 3 0 IncA protein DUF1980 PF09323.5 KZN94365.1 - 1.5 8.5 9.4 5.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Ribonuclease_T2 PF00445.13 KZN94366.1 - 2.1e-46 157.9 0.8 3.2e-46 157.3 0.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 KZN94366.1 - 0.034 13.7 0.4 0.1 12.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1792) BCNT PF07572.7 KZN94367.1 - 2.5e-27 94.6 0.7 7.3e-27 93.1 0.5 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.9 KZN94367.1 - 9.4 4.1 15.1 14 3.5 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein HlyIII PF03006.15 KZN94370.1 - 0.17 11.2 6.1 0.023 14.1 1.2 1.6 2 0 0 2 2 2 0 Haemolysin-III related DUF202 PF02656.10 KZN94370.1 - 1.4 9.1 9.6 2.2e+02 2.1 5.8 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Amidohydro_4 PF13147.1 KZN94371.1 - 3.1e-13 50.3 0.0 4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KZN94371.1 - 7.3e-06 25.7 0.0 1.4e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KZN94371.1 - 0.003 17.2 0.0 0.0087 15.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Mis12 PF05859.7 KZN94372.1 - 9.5e-45 151.9 0.0 1.7e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein CENP-X PF09415.5 KZN94374.1 - 1.9e-28 98.0 0.0 3.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 KZN94374.1 - 0.007 16.3 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndc1_Nup PF09531.5 KZN94374.1 - 0.4 9.0 10.4 0.52 8.6 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.4 KZN94374.1 - 2.9 6.4 15.6 3.3 6.2 10.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macro PF01661.16 KZN94375.1 - 9e-11 41.7 0.0 2.2e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Macro domain MIF PF01187.13 KZN94376.1 - 3e-07 30.5 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) bZIP_1 PF00170.16 KZN94377.1 - 0.01 15.7 0.4 0.019 14.9 0.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor Oxidored_FMN PF00724.15 KZN94378.1 - 4.1e-48 164.1 0.0 5.9e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Epimerase PF01370.16 KZN94379.1 - 1.7e-15 57.1 0.0 6.9e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KZN94379.1 - 6.5e-10 38.1 0.0 6.6e-09 34.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KZN94379.1 - 6.7e-10 39.2 0.2 4.5e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KZN94379.1 - 1.2e-06 28.5 0.7 9.9e-06 25.5 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KZN94379.1 - 2.2e-06 26.7 0.0 0.00011 21.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KZN94379.1 - 6.6e-05 22.2 0.1 0.00014 21.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KZN94379.1 - 0.0033 16.3 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KZN94379.1 - 0.005 16.5 0.4 0.66 9.6 0.2 2.8 2 1 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 KZN94380.1 - 1e-11 44.4 0.3 1.7e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN94380.1 - 2.9e-08 33.4 0.1 2.6e-07 30.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KZN94381.1 - 7.7e-23 81.2 1.5 7.7e-23 81.2 1.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN94381.1 - 1.9e-07 31.1 0.4 2.5e-07 30.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN94381.1 - 2.2e-07 30.6 0.4 5.2e-07 29.5 0.3 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 KZN94381.1 - 1e-05 24.8 0.0 0.047 12.8 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KZN94381.1 - 0.0005 20.1 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding ParD PF09386.5 KZN94381.1 - 0.029 14.4 0.8 0.4 10.8 0.1 2.3 1 1 1 2 2 2 0 Antitoxin ParD NmrA PF05368.8 KZN94382.1 - 4.8e-29 101.2 0.0 4.3e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KZN94382.1 - 2.5e-07 30.9 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KZN94382.1 - 6.4e-06 26.1 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KZN94382.1 - 0.0056 15.4 0.0 0.0076 14.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KZN94382.1 - 0.0075 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KZN94382.1 - 0.014 15.2 0.1 0.029 14.2 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.20 KZN94383.1 - 6.2e-06 25.5 0.0 7.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Phage_Coat_B PF05356.6 KZN94385.1 - 0.021 14.5 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Phage Coat protein B Tme5_EGF_like PF09064.5 KZN94385.1 - 0.085 12.4 1.9 3.5 7.3 0.2 2.8 2 1 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Claudin_2 PF13903.1 KZN94385.1 - 0.18 11.4 5.7 0.42 10.2 3.9 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction A_deaminase PF00962.17 KZN94386.1 - 4e-42 144.3 0.0 5.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase His_Phos_2 PF00328.17 KZN94387.1 - 1.8e-30 106.4 0.0 2.3e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.17 KZN94388.1 - 2e-186 619.8 0.4 2.2e-186 619.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 KZN94389.1 - 3.9e-15 55.7 1.2 4.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KZN94389.1 - 2.8e-08 33.6 0.3 8.2e-08 32.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN94389.1 - 3.7e-08 32.6 4.3 1.2e-06 27.7 2.7 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KZN94389.1 - 2.9e-05 23.3 0.2 0.029 13.4 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KZN94389.1 - 0.00013 21.9 0.0 0.00036 20.4 0.1 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN94389.1 - 0.00025 20.0 0.1 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KZN94389.1 - 0.00097 19.5 0.5 0.0027 18.0 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KZN94389.1 - 0.0014 17.6 3.7 0.0024 16.8 2.3 1.5 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KZN94389.1 - 0.0028 16.8 0.1 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KZN94389.1 - 0.015 14.1 1.7 0.015 14.1 1.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Rossmann-like PF10727.4 KZN94389.1 - 0.022 14.4 0.2 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.1 KZN94389.1 - 0.033 14.2 0.2 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KZN94389.1 - 0.036 13.7 1.8 0.073 12.7 1.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KZN94389.1 - 0.047 13.5 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KZN94389.1 - 0.09 12.4 0.7 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 KZN94389.1 - 0.11 10.9 1.9 0.16 10.3 1.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KZN94389.1 - 0.25 9.9 4.0 1.5 7.3 1.2 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Fungal_trans PF04082.13 KZN94393.1 - 3e-17 62.3 0.0 6.7e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94393.1 - 1.6e-05 24.7 8.7 3.2e-05 23.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Smg4_UPF3 PF03467.10 KZN94394.1 - 4.2e-21 75.7 0.0 4.2e-21 75.7 0.0 2.6 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 KZN94394.1 - 1.5e-08 34.0 0.0 7.4e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN94394.1 - 3.5e-08 33.2 0.0 5e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN94394.1 - 4.4e-05 23.2 0.0 0.00014 21.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M19 PF01244.16 KZN94395.1 - 1e-100 336.8 0.0 1.2e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M35 PF02102.10 KZN94396.1 - 2.5e-180 598.7 11.9 2.8e-180 598.6 8.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 KZN94396.1 - 4.6e-07 30.4 0.8 1e-06 29.3 0.6 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pox_RNA_Pol_22 PF05273.8 KZN94396.1 - 0.032 13.8 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus RNA polymerase 22 kDa subunit HMGL-like PF00682.14 KZN94396.1 - 0.039 13.6 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 HMGL-like CARDB PF07705.6 KZN94396.1 - 0.04 13.9 0.2 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 CARDB Sua5_yciO_yrdC PF01300.13 KZN94398.1 - 8.2e-11 41.4 0.0 2.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination DUF2335 PF10097.4 KZN94398.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Peptidase_A4 PF01828.12 KZN94399.1 - 1.1e-78 263.1 1.0 1.3e-78 262.8 0.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family PHY PF00360.15 KZN94400.1 - 7e-28 96.9 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KZN94400.1 - 2.3e-17 62.7 0.1 5.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KZN94400.1 - 1.4e-15 57.2 0.1 3.1e-14 52.9 0.0 3.1 3 1 0 3 3 3 1 Response regulator receiver domain GAF PF01590.21 KZN94400.1 - 2.8e-15 56.7 0.0 1.8e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 KZN94400.1 - 2.2e-11 43.5 0.7 6.6e-11 42.0 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KZN94400.1 - 6.4e-10 39.4 0.0 1.8e-08 34.7 0.0 2.8 2 0 0 2 2 2 1 PAS fold F-box PF00646.28 KZN94402.1 - 0.097 12.3 1.4 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 F-box domain Bac_rhamnosid PF05592.6 KZN94405.1 - 7.2e-191 634.8 0.0 8.6e-191 634.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KZN94405.1 - 4.1e-55 185.9 0.0 1.2e-54 184.4 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.6 KZN94406.1 - 1.3e-128 429.3 0.0 1.7e-128 429.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KZN94406.1 - 6.4e-51 172.2 0.0 1e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 KZN94406.1 - 0.0078 14.9 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Metallophos PF00149.23 KZN94407.1 - 4.5e-11 42.5 2.0 7.7e-11 41.7 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN94407.1 - 5.3e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_ligase_ZBD PF03119.11 KZN94407.1 - 0.051 13.2 0.1 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Sugar_tr PF00083.19 KZN94408.1 - 6e-100 334.9 27.6 6.9e-100 334.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN94408.1 - 4.5e-29 101.2 39.1 3.5e-26 91.7 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 KZN94408.1 - 0.0052 15.1 0.4 0.0052 15.1 0.3 2.0 2 0 0 2 2 2 1 Membrane transport protein Lysis_S PF04971.7 KZN94408.1 - 0.094 12.4 2.6 2 8.1 0.1 2.9 2 0 0 2 2 2 0 Lysis protein S PAD_M PF08527.5 KZN94412.1 - 0.063 12.6 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain PIF1 PF05970.9 KZN94413.1 - 5.3e-22 78.2 0.0 7.8e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KZN94413.1 - 2.1e-07 30.6 0.0 1.2e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN94413.1 - 0.00012 21.7 0.5 0.00035 20.2 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KZN94413.1 - 0.0093 15.5 0.2 4.4 6.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 KZN94413.1 - 0.03 13.3 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 KZN94413.1 - 0.051 13.7 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain QLQ PF08880.6 KZN94414.1 - 0.73 9.2 2.0 16 5.0 0.0 2.9 3 0 0 3 3 3 0 QLQ DUF4224 PF13986.1 KZN94415.1 - 0.049 13.1 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) AphA_like PF14557.1 KZN94416.1 - 0.033 13.7 0.5 0.059 12.9 0.4 1.4 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator RPW8 PF05659.6 KZN94416.1 - 0.094 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Siah-Interact_N PF09032.6 KZN94416.1 - 1.9 8.6 8.2 0.39 10.7 0.7 2.6 2 1 0 2 2 2 0 Siah interacting protein, N terminal GvpG PF05120.7 KZN94416.1 - 6.9 6.5 8.5 0.96 9.3 0.0 2.8 3 0 0 3 3 3 0 Gas vesicle protein G PsiA PF06952.6 KZN94417.1 - 0.076 12.0 0.9 0.12 11.4 0.7 1.2 1 0 0 1 1 1 0 PsiA protein MutS_III PF05192.13 KZN94417.1 - 0.095 12.4 0.2 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 MutS domain III SUR7 PF06687.7 KZN94418.1 - 2.8e-28 98.9 12.9 3.7e-28 98.5 9.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family SOG2 PF10428.4 KZN94418.1 - 0.28 9.8 0.5 0.34 9.5 0.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3433 PF11915.3 KZN94419.1 - 5e-41 138.7 20.4 5.6e-31 106.5 1.7 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) G-patch PF01585.18 KZN94421.1 - 4.4e-13 48.7 0.3 7.8e-13 47.9 0.2 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 KZN94421.1 - 3.6e-09 36.1 0.0 0.00061 19.3 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KZN94421.1 - 2.3e-08 33.7 0.4 6.3e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KZN94421.1 - 9.2e-08 31.0 1.7 1.9e-07 30.0 1.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 KZN94421.1 - 9.1e-06 25.5 0.0 0.098 12.6 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Alpha-amylase PF00128.19 KZN94422.1 - 2.5e-95 319.5 4.2 4.4e-95 318.7 2.9 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MoaE PF02391.12 KZN94423.1 - 4.1e-29 100.7 0.0 5.2e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 KZN94424.1 - 4.5e-59 198.9 0.0 6.3e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KZN94424.1 - 9.3e-06 25.3 0.6 3.6e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KZN94424.1 - 2.7e-05 24.2 0.1 6.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 KZN94424.1 - 0.12 11.9 0.0 0.33 10.4 0.0 1.9 1 1 0 1 1 1 0 Redoxin Phosphoesterase PF04185.9 KZN94425.1 - 4.5e-61 207.1 0.2 7.9e-61 206.3 0.1 1.4 1 1 0 1 1 1 1 Phosphoesterase family FAD_binding_3 PF01494.14 KZN94426.1 - 1.5e-82 277.4 0.1 1.9e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KZN94426.1 - 2.7e-05 24.4 0.3 0.0043 17.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KZN94426.1 - 3.4e-05 23.7 0.1 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KZN94426.1 - 4.1e-05 22.6 0.3 0.00012 21.1 0.2 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KZN94426.1 - 0.00052 18.5 0.0 0.0014 17.1 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KZN94426.1 - 0.00088 18.2 0.1 0.0019 17.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KZN94426.1 - 0.00095 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KZN94426.1 - 0.002 17.0 0.0 0.0063 15.3 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KZN94426.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KZN94426.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KZN94426.1 - 0.018 14.0 0.4 0.034 13.0 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KZN94426.1 - 0.019 14.7 0.1 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KZN94426.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KZN94426.1 - 0.056 13.7 0.0 0.85 9.9 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.11 KZN94426.1 - 0.094 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 KZN94427.1 - 1.2e-19 70.2 0.0 2.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3469 PF11952.3 KZN94428.1 - 0.068 12.8 0.1 0.55 9.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3469) Fungal_trans PF04082.13 KZN94429.1 - 2.6e-08 33.0 0.9 5.5e-08 32.0 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE PF05739.14 KZN94430.1 - 8.8e-18 63.7 2.3 1.9e-17 62.6 0.5 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KZN94430.1 - 3.8e-15 55.9 1.5 2.7e-14 53.1 0.1 2.5 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KZN94430.1 - 0.0073 15.8 1.0 0.0073 15.8 0.7 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 KZN94430.1 - 0.047 13.7 0.3 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Sed5p PF11416.3 KZN94430.1 - 0.074 12.5 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p NPV_P10 PF05531.7 KZN94430.1 - 0.28 11.4 2.3 83 3.5 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DIOX_N PF14226.1 KZN94432.1 - 1e-30 106.6 0.0 1.6e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KZN94432.1 - 3.2e-24 85.0 0.0 5.1e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily E1-E2_ATPase PF00122.15 KZN94433.1 - 4.1e-69 232.1 0.5 4.1e-69 232.1 0.4 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KZN94433.1 - 2.1e-23 83.9 0.0 1.1e-22 81.4 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN94433.1 - 5.2e-13 49.5 0.0 1.3e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KZN94433.1 - 4.8e-10 38.7 0.5 1.4e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KZN94433.1 - 0.0017 17.9 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KZN94433.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Lactamase_B PF00753.22 KZN94434.1 - 3.1e-10 40.0 1.5 1.4e-09 37.9 1.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KZN94434.1 - 0.00017 21.1 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UPF0258 PF06789.7 KZN94434.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) ABC1 PF03109.11 KZN94436.1 - 4e-20 71.9 0.3 1.9e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 KZN94436.1 - 0.0057 16.4 0.1 0.027 14.1 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family SnoaL_2 PF12680.2 KZN94437.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain TFIIS_M PF07500.9 KZN94438.1 - 1.1e-26 93.1 0.2 2.6e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KZN94438.1 - 4.7e-18 64.5 4.8 9.2e-18 63.5 3.3 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KZN94438.1 - 1.6e-12 46.7 0.3 3.7e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 KZN94438.1 - 0.0094 15.3 1.3 0.024 14.0 0.9 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain MFS_1 PF07690.11 KZN94439.1 - 3.5e-35 121.3 37.3 1.8e-34 119.0 25.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KZN94439.1 - 0.055 13.5 0.7 0.055 13.5 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) FixH PF05751.6 KZN94439.1 - 2.3 8.0 0.0 2.3 8.0 0.0 2.6 2 1 1 3 3 3 0 FixH DUF4149 PF13664.1 KZN94439.1 - 9 6.4 18.0 7.7 6.6 1.9 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4149) Myb_DNA-bind_6 PF13921.1 KZN94440.1 - 4.2e-05 23.5 0.0 8.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 KZN94441.1 - 3.6e-10 39.4 0.0 6.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KZN94441.1 - 1.7e-06 27.2 0.0 5.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KZN94441.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KZN94441.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KZN94441.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AAA PF00004.24 KZN94442.1 - 2.2e-19 69.9 0.1 1.1e-17 64.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KZN94442.1 - 0.00013 22.7 0.4 0.00061 20.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KZN94442.1 - 0.01 16.1 0.1 0.043 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KZN94442.1 - 0.019 15.0 2.3 4.6 7.4 0.0 3.2 2 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KZN94442.1 - 0.042 13.8 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KZN94442.1 - 0.066 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KZN94442.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DEAD PF00270.24 KZN94442.1 - 0.1 12.0 0.2 0.94 8.9 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 KZN94442.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Kdo PF06293.9 KZN94443.1 - 0.00023 20.3 0.0 0.0005 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KZN94443.1 - 0.0026 17.5 8.3 0.013 15.2 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 KZN94443.1 - 0.015 14.4 0.0 0.038 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain DUF3584 PF12128.3 KZN94443.1 - 0.082 10.2 16.0 0.12 9.6 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RIO1 PF01163.17 KZN94443.1 - 0.2 10.9 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 1 0 RIO1 family Tom37_C PF11801.3 KZN94443.1 - 0.68 9.7 3.7 1.6 8.6 2.5 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Ycf1 PF05758.7 KZN94443.1 - 0.73 7.4 4.1 1 7.0 2.8 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 KZN94443.1 - 1.2 8.5 13.3 2.5 7.5 9.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MAP7 PF05672.6 KZN94443.1 - 1.9 7.8 35.1 4.7 6.5 24.4 1.6 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family eIF3_subunit PF08597.5 KZN94443.1 - 3.4 7.1 15.8 6.7 6.2 11.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF605 PF04652.11 KZN94443.1 - 7.9 5.7 22.0 0.13 11.6 8.3 2.1 2 0 0 2 2 2 0 Vta1 like gag_pre-integrs PF13976.1 KZN94445.1 - 3e-06 26.7 0.0 5.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KZN94445.1 - 5.5e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_18 PF12833.2 KZN94445.1 - 0.0056 16.7 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DUF1814 PF08843.6 KZN94446.1 - 0.0014 18.4 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_2 PF01909.18 KZN94446.1 - 0.06 13.6 0.0 8.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain Metallophos PF00149.23 KZN94447.1 - 8.9e-07 28.4 1.0 3.1e-06 26.7 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KZN94447.1 - 0.00015 21.6 0.3 0.0003 20.6 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain E1-E2_ATPase PF00122.15 KZN94448.1 - 5.9e-50 169.4 5.7 1e-49 168.6 4.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN94448.1 - 5.2e-22 79.3 0.0 9.4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KZN94448.1 - 1.4e-13 51.4 0.0 2.9e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN94448.1 - 5.3e-05 23.2 0.1 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KZN94448.1 - 0.00015 21.4 0.0 0.00048 19.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 KZN94448.1 - 0.0081 15.6 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Cu-oxidase_2 PF07731.9 KZN94450.1 - 1.1e-43 148.0 8.2 5.9e-37 126.2 1.6 4.7 4 2 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN94450.1 - 1.5e-42 144.0 2.4 3.1e-40 136.5 0.0 4.1 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.17 KZN94450.1 - 3.7e-20 72.4 1.9 2.2e-13 50.4 0.0 3.3 2 1 0 3 3 3 2 Multicopper oxidase E1-E2_ATPase PF00122.15 KZN94451.1 - 7.7e-49 165.7 0.0 2.2e-48 164.2 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KZN94451.1 - 3.6e-35 122.3 0.5 6.8e-35 121.4 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KZN94451.1 - 1.2e-28 99.0 0.2 1e-11 44.7 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KZN94451.1 - 2.3e-15 57.2 0.0 5.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KZN94451.1 - 1.2e-05 25.0 0.1 4.9e-05 23.0 0.0 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase BIR PF00653.16 KZN94452.1 - 7.9e-05 22.9 0.4 0.00012 22.3 0.2 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KZN94452.1 - 0.023 14.4 3.4 0.88 9.3 2.3 2.1 1 1 0 1 1 1 0 C3HC zinc finger-like DUF3435 PF11917.3 KZN94453.1 - 1.6e-06 27.1 0.0 2.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3841 PF12952.2 KZN94453.1 - 0.058 12.8 0.2 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Herpes_LAMP2 PF06126.6 KZN94454.1 - 0.084 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Cu-oxidase_2 PF07731.9 KZN94455.1 - 3.7e-43 146.3 4.8 2.3e-36 124.3 0.3 3.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KZN94455.1 - 7e-41 138.6 5.5 2.9e-40 136.6 0.1 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 KZN94455.1 - 4.2e-21 75.5 0.3 1.9e-15 57.0 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Zip PF02535.17 KZN94456.1 - 1.3e-47 162.4 4.0 1.6e-47 162.0 2.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3435 PF11917.3 KZN94458.1 - 3.3e-148 493.8 3.4 5.5e-148 493.1 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) UPF0278 PF08745.6 KZN94458.1 - 0.018 14.3 2.3 0.035 13.3 1.6 1.4 1 0 0 1 1 1 0 UPF0278 family Aa_trans PF01490.13 KZN94459.1 - 1.3e-46 158.8 36.0 1.6e-46 158.6 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 KZN94460.1 - 5.2e-16 58.2 6.3 5.2e-16 58.2 4.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KZN94460.1 - 0.0011 17.5 5.0 0.48 8.8 0.0 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 KZN94460.1 - 0.003 16.2 0.8 0.0052 15.4 0.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_71 PF03659.9 KZN94461.1 - 3.9e-140 466.7 12.7 5.6e-140 466.1 8.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.1 KZN94461.1 - 7.7e-15 55.4 0.2 1.6e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KZN94461.1 - 0.00078 19.3 2.2 0.0025 17.6 1.5 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_6 PF13516.1 KZN94463.1 - 4.6e-10 38.5 2.9 0.14 12.2 0.1 7.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 KZN94463.1 - 9.4e-10 37.9 0.8 0.00035 20.1 0.0 4.5 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KZN94463.1 - 0.0012 18.5 4.6 0.037 13.7 0.1 4.1 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KZN94463.1 - 0.0015 18.3 6.7 1.4 9.2 0.1 5.8 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 KZN94463.1 - 0.011 15.8 1.8 67 4.3 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat COX17 PF05051.8 KZN94464.1 - 2e-21 75.7 6.5 2.7e-21 75.3 4.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KZN94464.1 - 0.015 15.0 2.9 0.22 11.2 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 KZN94464.1 - 0.17 11.7 2.7 0.39 10.6 1.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Alg6_Alg8 PF03155.10 KZN94465.1 - 2.6e-130 435.4 16.5 5e-82 276.2 4.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 KZN94466.1 - 4e-45 151.3 0.1 3.9e-21 74.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KZN94466.1 - 6.5e-36 122.1 0.0 4.2e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KZN94466.1 - 1.4e-17 63.2 0.0 4.9e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_pp38 PF04846.8 KZN94467.1 - 0.014 14.6 0.4 0.032 13.5 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein HemY_N PF07219.8 KZN94467.1 - 0.28 10.7 1.6 0.81 9.2 1.1 1.8 1 0 0 1 1 1 0 HemY protein N-terminus FMN_bind_2 PF04299.7 KZN94468.1 - 6.4e-55 185.2 0.1 7.6e-55 184.9 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Ring_hydroxyl_A PF00848.14 KZN94469.1 - 3.9e-30 105.0 1.4 1.1e-29 103.6 1.0 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KZN94469.1 - 1.6e-15 56.4 0.0 3.5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Dioxygenase_C PF00775.16 KZN94470.1 - 4.3e-44 149.9 0.0 5.6e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KZN94470.1 - 1.5e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus NAD_binding_10 PF13460.1 KZN94472.1 - 0.00015 21.8 0.0 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KZN94472.1 - 0.031 13.0 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MoCF_biosynth PF00994.19 KZN94473.1 - 2.3e-32 111.3 0.0 6.3e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KZN94473.1 - 4.4e-27 94.4 0.2 6.5e-27 93.8 0.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KZN94473.1 - 2.6e-10 40.1 0.1 7.1e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) MFS_1 PF07690.11 KZN94475.1 - 1.1e-32 113.1 31.2 1.1e-32 113.1 21.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.1 KZN94476.1 - 3.3e-24 85.9 0.0 4.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KZN94476.1 - 1e-23 84.0 0.4 1.3e-23 83.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KZN94476.1 - 9.7e-09 35.1 0.0 1.5e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN94476.1 - 0.06 13.3 0.3 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding Fungal_trans_2 PF11951.3 KZN94477.1 - 5.8e-13 48.1 0.0 1.3e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94477.1 - 1.4e-07 31.2 10.3 1.4e-07 31.2 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 KZN94478.1 - 1e-117 392.7 0.1 4.7e-117 390.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KZN94478.1 - 2.5e-39 134.6 0.2 5.5e-39 133.4 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KZN94478.1 - 6.7e-08 31.7 0.0 2.4e-06 26.6 0.0 2.5 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KZN94478.1 - 1.2e-06 27.4 0.1 2.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KZN94478.1 - 6.4e-05 22.5 2.5 0.0017 17.9 0.8 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.15 KZN94478.1 - 0.0041 17.0 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain GSHPx PF00255.14 KZN94478.1 - 0.017 14.4 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Glutathione peroxidase Fungal_trans PF04082.13 KZN94479.1 - 1.9e-15 56.4 3.3 3e-15 55.8 2.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94479.1 - 7.2e-09 35.4 10.8 1.2e-08 34.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KZN94480.1 - 5.9e-10 38.8 0.1 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KZN94480.1 - 2.3e-06 27.1 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LysM PF01476.15 KZN94482.1 - 1.1e-10 41.2 0.2 5.5e-05 22.9 0.2 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KZN94482.1 - 0.0003 20.7 6.1 0.0003 20.7 4.2 2.7 2 0 0 2 2 2 1 Chitin recognition protein Glyco_hydro_72 PF03198.9 KZN94485.1 - 3.9e-132 439.9 2.4 4.8e-132 439.7 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KZN94485.1 - 5.8e-06 25.7 0.4 0.00015 21.0 0.3 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KZN94485.1 - 0.0094 14.8 0.2 0.029 13.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FA_hydroxylase PF04116.8 KZN94486.1 - 2.2e-15 57.0 15.6 2.2e-15 57.0 10.8 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Tyrosinase PF00264.15 KZN94488.1 - 9.3e-46 156.7 0.2 1.1e-45 156.4 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAM196 PF15265.1 KZN94489.1 - 0.02 14.1 22.7 0.022 14.0 15.7 1.0 1 0 0 1 1 1 0 FAM196 family DUF605 PF04652.11 KZN94489.1 - 0.045 13.1 28.7 0.055 12.8 19.9 1.1 1 0 0 1 1 1 0 Vta1 like CytochromB561_N PF09786.4 KZN94489.1 - 0.61 8.4 22.5 0.7 8.2 15.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Utp14 PF04615.8 KZN94489.1 - 0.96 7.5 11.2 1.1 7.3 7.7 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 KZN94489.1 - 9.3 4.3 26.5 13 3.9 18.4 1.2 1 0 0 1 1 1 0 Transmembrane protein AvrE PF11725.3 KZN94489.1 - 9.4 3.0 20.4 11 2.8 14.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor UQ_con PF00179.21 KZN94490.1 - 8.7e-37 125.6 0.0 9.6e-37 125.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KZN94490.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.3 1 1 0 1 1 1 1 RWD domain HhH-GPD PF00730.20 KZN94491.1 - 9.3e-20 70.9 0.0 3.3e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KZN94491.1 - 6.6e-08 31.8 0.2 2.8e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.1 KZN94492.1 - 4.4e-65 219.5 0.1 8.6e-65 218.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KZN94492.1 - 5.4e-56 189.1 0.0 8.7e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KZN94492.1 - 1.3e-14 53.6 0.3 1.3e-13 50.5 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KZN94492.1 - 5.6e-12 45.6 0.0 1e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KZN94492.1 - 1.2e-07 31.4 0.0 0.12 11.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KZN94492.1 - 7.6e-07 28.4 0.2 2.4e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KZN94492.1 - 1.3e-06 28.3 0.0 8.6e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KZN94492.1 - 2.9e-06 27.4 0.1 0.00015 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KZN94492.1 - 2e-05 24.1 0.1 0.00028 20.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KZN94492.1 - 5.9e-05 22.5 0.0 0.00015 21.1 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KZN94492.1 - 7.6e-05 22.0 0.0 0.015 14.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 KZN94492.1 - 0.0002 21.0 0.0 0.013 15.1 0.0 2.4 1 1 0 1 1 1 1 Helicase Flavi_DEAD PF07652.9 KZN94492.1 - 0.00047 19.9 0.1 0.0021 17.8 0.1 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain PIF1 PF05970.9 KZN94492.1 - 0.00066 18.7 0.0 0.5 9.2 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase T2SE PF00437.15 KZN94492.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 KZN94492.1 - 0.0017 18.3 0.0 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C PF13361.1 KZN94492.1 - 0.0037 16.7 0.1 2.8 7.2 0.0 2.7 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 KZN94492.1 - 0.005 16.5 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KZN94492.1 - 0.0058 16.0 0.0 0.019 14.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KZN94492.1 - 0.011 14.4 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 KZN94492.1 - 0.016 14.6 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KZN94492.1 - 0.027 14.6 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 KZN94492.1 - 0.035 13.5 0.2 0.13 11.6 0.2 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.7 KZN94492.1 - 0.051 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 KZN94492.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 KZN94492.1 - 0.057 12.8 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain SKI PF01202.17 KZN94492.1 - 0.078 12.8 0.3 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Shikimate kinase Mg_chelatase PF01078.16 KZN94492.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_3 PF01494.14 KZN94493.1 - 4.8e-12 45.6 1.1 4.8e-12 45.6 0.8 1.9 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 KZN94493.1 - 0.013 14.3 0.0 0.07 11.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.19 KZN94493.1 - 0.065 12.2 0.9 0.096 11.7 0.1 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KZN94493.1 - 0.094 12.7 0.2 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 KZN94494.1 - 3.9e-14 52.9 0.0 6.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN94494.1 - 1.8e-08 34.4 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KZN94494.1 - 3.1e-05 23.5 0.0 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KZN94494.1 - 0.0012 18.5 0.0 0.0054 16.4 0.0 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KZN94494.1 - 0.035 13.8 0.3 0.077 12.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3712 PF12505.3 KZN94495.1 - 6.1e-32 110.2 0.1 1.1e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ESSS PF10183.4 KZN94495.1 - 0.013 15.8 0.2 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1279 PF06916.8 KZN94495.1 - 0.081 13.2 0.5 0.53 10.6 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) LEA_2 PF03168.8 KZN94495.1 - 0.1 12.9 0.3 0.64 10.4 0.1 2.3 2 1 0 2 2 2 0 Late embryogenesis abundant protein Sel1 PF08238.7 KZN94496.1 - 5.4e-15 55.4 5.3 0.00023 21.7 0.6 4.3 4 0 0 4 4 4 3 Sel1 repeat DUF1776 PF08643.5 KZN94499.1 - 4.5e-102 341.2 0.0 5.3e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 KZN94500.1 - 2.6e-57 193.7 0.2 3.8e-57 193.1 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KZN94500.1 - 0.00098 18.1 3.5 0.00098 18.1 2.5 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KZN94500.1 - 0.096 12.4 0.7 0.23 11.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 SprT-like PF10263.4 KZN94500.1 - 0.099 12.2 0.1 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 SprT-like family DZR PF12773.2 KZN94500.1 - 2 8.2 13.1 46 3.9 9.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 KZN94501.1 - 1.4e-68 224.4 25.4 3.9e-08 32.8 0.3 11.5 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 KZN94501.1 - 1.6e-21 76.2 0.4 2.6e-21 75.5 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KZN94501.1 - 7.3e-09 34.2 0.9 0.015 13.5 0.0 5.4 5 1 1 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KZN94501.1 - 0.0021 17.5 1.7 0.7 9.3 0.3 2.8 2 0 0 2 2 2 2 PQQ-like domain DUF3312 PF11768.3 KZN94501.1 - 0.0053 15.0 0.0 0.11 10.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 KZN94501.1 - 0.011 14.5 1.5 8.3 5.0 0.0 4.0 2 1 2 5 5 5 0 Nup133 N terminal like Utp13 PF08625.6 KZN94501.1 - 0.033 13.8 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain UTP15_C PF09384.5 KZN94501.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 UTP15 C terminal P34-Arc PF04045.9 KZN94502.1 - 7.1e-104 346.3 0.1 8.6e-104 346.0 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 KZN94503.1 - 3.2e-28 96.5 5.7 7.5e-08 31.9 0.5 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KZN94503.1 - 2.6e-06 25.8 1.4 0.0013 17.0 0.1 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Cmc1 PF08583.5 KZN94504.1 - 8.7e-17 60.6 4.3 1.1e-16 60.3 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 KZN94504.1 - 0.28 11.3 2.2 0.49 10.5 1.3 1.5 1 1 0 1 1 1 0 GCK domain Fcf1 PF04900.7 KZN94505.1 - 2.3e-11 43.6 0.1 0.00025 21.0 0.0 2.9 2 1 0 2 2 2 2 Fcf1 PP2C PF00481.16 KZN94506.1 - 0.0007 19.0 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KZN94506.1 - 0.0059 16.3 0.0 0.025 14.2 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Beta-lactamase PF00144.19 KZN94508.1 - 3.4e-41 141.3 0.8 4.6e-41 140.9 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase DIE2_ALG10 PF04922.7 KZN94509.1 - 2.8e-71 240.5 20.4 3.1e-65 220.6 9.0 3.0 2 1 0 2 2 2 2 DIE2/ALG10 family DUF3377 PF11857.3 KZN94509.1 - 0.71 9.5 2.3 1.5 8.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Sld5 PF05916.6 KZN94510.1 - 8.7e-30 103.1 0.0 1.3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.11 KZN94511.1 - 1.6e-11 43.4 0.0 2.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 KZN94512.1 - 2.9e-64 216.3 21.7 1.7e-63 213.8 15.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KZN94512.1 - 1e-21 77.1 5.8 1.6e-21 76.4 0.3 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KZN94512.1 - 1.8e-13 51.1 9.9 1.2e-05 25.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KZN94512.1 - 8.5e-05 22.0 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KZN94512.1 - 0.0058 15.8 35.5 0.33 10.1 0.7 5.6 3 2 3 6 6 6 3 Reovirus sigma C capsid protein Methyltransf_31 PF13847.1 KZN94513.1 - 2.1e-12 46.8 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN94513.1 - 1.9e-10 41.0 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KZN94513.1 - 3e-10 39.6 0.0 4.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KZN94513.1 - 4e-07 30.3 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN94513.1 - 4.6e-07 30.2 0.0 7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KZN94513.1 - 3.8e-06 26.9 0.0 1e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KZN94513.1 - 8.6e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KZN94513.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KZN94513.1 - 0.0017 18.8 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KZN94513.1 - 0.027 14.1 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NOT2_3_5 PF04153.13 KZN94514.1 - 1e-33 116.0 0.0 4e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 KZN94515.1 - 1.2e-20 73.2 0.0 1.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 KZN94515.1 - 0.0057 15.9 0.8 0.0092 15.2 0.5 1.3 1 0 0 1 1 1 1 Clc-like GDI PF00996.13 KZN94516.1 - 2.5e-182 606.1 0.0 3e-182 605.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KZN94516.1 - 0.05 13.6 0.1 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 4HBT PF03061.17 KZN94517.1 - 3.7e-12 46.2 0.0 5.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KZN94517.1 - 0.11 12.9 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily ORC4_C PF14629.1 KZN94518.1 - 1.6e-56 190.8 0.0 2.4e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KZN94518.1 - 4.5e-18 65.9 0.5 2.5e-17 63.4 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KZN94518.1 - 2e-08 34.4 0.0 5.8e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KZN94518.1 - 5.2e-07 29.4 0.1 1.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KZN94518.1 - 8.6e-06 25.6 0.0 1.9e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KZN94518.1 - 2.4e-05 24.4 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KZN94518.1 - 8.9e-05 21.6 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 KZN94518.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 KZN94518.1 - 0.0023 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 KZN94518.1 - 0.016 13.9 0.5 0.059 12.0 0.3 2.0 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 KZN94518.1 - 0.028 14.7 0.0 0.075 13.3 0.0 1.7 2 0 0 2 2 1 0 ABC transporter PIF1 PF05970.9 KZN94518.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.1 KZN94518.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KZN94518.1 - 0.04 13.8 0.0 0.13 12.1 0.0 2.1 2 1 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KZN94518.1 - 0.055 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KZN94518.1 - 0.12 11.8 1.1 0.19 11.2 0.0 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family Nucleoplasmin PF03066.10 KZN94518.1 - 0.96 8.9 8.7 1.5 8.3 5.0 1.9 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 KZN94518.1 - 1 8.9 8.9 2.6 7.6 6.1 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KZN94518.1 - 1.7 7.8 3.9 2.6 7.2 2.7 1.3 1 0 0 1 1 1 0 NOA36 protein RGS PF00615.14 KZN94519.1 - 1.9e-34 118.2 0.1 4.2e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KZN94519.1 - 3.2e-24 84.4 0.1 2.8e-18 65.4 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_tran_WbsX PF14307.1 KZN94519.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX CDC73 PF05179.9 KZN94520.1 - 2.6e-43 148.3 0.0 6.8e-43 146.9 0.0 1.7 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family MFS_1 PF07690.11 KZN94520.1 - 3.9e-13 48.8 38.4 3.9e-13 48.8 26.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily SET PF00856.23 KZN94521.1 - 1.2e-07 32.1 1.4 4.3e-07 30.3 0.0 2.5 3 0 0 3 3 3 1 SET domain PHD PF00628.24 KZN94521.1 - 4.6e-06 26.2 9.3 8.4e-06 25.3 6.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF3827 PF12877.2 KZN94521.1 - 0.8 7.7 5.6 1.6 6.7 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) AA_permease PF00324.16 KZN94522.1 - 5.9e-50 169.9 36.1 3.8e-49 167.3 25.0 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KZN94522.1 - 1.6e-14 53.3 32.3 3.9e-14 52.0 22.4 1.6 1 1 0 1 1 1 1 Amino acid permease WD40 PF00400.27 KZN94523.1 - 1.9e-22 78.2 9.2 1.7e-05 24.5 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 KZN94524.1 - 1.5e-30 106.0 11.3 1.5e-30 106.0 7.9 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 4 MFS_1 PF07690.11 KZN94525.1 - 1.9e-08 33.4 32.7 1.9e-08 33.4 22.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KZN94525.1 - 1.5e-07 31.0 4.1 1.5e-07 31.0 2.9 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 ADH_zinc_N PF00107.21 KZN94526.1 - 2.4e-12 46.5 0.0 4.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KZN94526.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KZN94526.1 - 0.00028 21.7 0.0 0.00052 20.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aconitase PF00330.15 KZN94527.1 - 5.3e-180 598.8 0.1 6.3e-180 598.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KZN94527.1 - 8.6e-44 148.8 0.0 1.7e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Alpha-amylase PF00128.19 KZN94528.1 - 1.9e-16 60.3 0.1 1.3e-15 57.6 0.1 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KZN94528.1 - 3.6e-14 52.8 0.2 6.1e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KZN94528.1 - 3.8e-05 23.8 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KZN94528.1 - 0.0001 21.7 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.22 KZN94529.1 - 2.8e-15 56.1 0.3 4.9e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.12 KZN94530.1 - 1.2e-115 385.5 0.0 1.9e-115 384.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ArgK PF03308.11 KZN94530.1 - 0.077 11.7 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF4515 PF14988.1 KZN94531.1 - 0.069 12.8 1.4 0.1 12.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) VGCC_beta4Aa_N PF12052.3 KZN94531.1 - 0.91 9.4 5.5 0.11 12.3 0.6 1.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF2418 PF10332.4 KZN94532.1 - 1.1e-37 128.3 0.7 2.4e-37 127.2 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 KZN94533.1 - 3.1e-31 107.6 0.0 3.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 KZN94533.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.10 KZN94534.1 - 1.2e-26 93.4 0.3 1.6e-26 93.1 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KZN94534.1 - 5.9e-05 23.1 0.0 0.00021 21.3 0.0 1.8 1 1 0 1 1 1 1 ML-like domain DIM PF08194.7 KZN94534.1 - 0.12 12.3 1.3 0.21 11.5 0.9 1.4 1 0 0 1 1 1 0 DIM protein AMP-binding PF00501.23 KZN94535.1 - 4e-64 216.5 0.0 5.1e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KZN94535.1 - 8.6e-05 23.4 0.0 0.00017 22.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 KZN94536.1 - 4.3e-67 225.8 0.6 4.3e-67 225.8 0.4 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KZN94536.1 - 1.5e-42 143.8 0.1 3.4e-42 142.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KZN94536.1 - 0.00022 20.7 0.8 0.0096 15.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KZN94536.1 - 0.0047 16.9 0.0 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KZN94536.1 - 0.014 14.8 0.9 0.047 13.1 0.5 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain APH PF01636.18 KZN94537.1 - 2.3e-07 30.8 0.2 6.7e-07 29.2 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Arv1 PF04161.8 KZN94538.1 - 1.2e-41 142.9 0.0 5.6e-36 124.4 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 KZN94539.1 - 2.4e-25 88.3 2.3 2.6e-25 88.2 1.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Polysacc_synt_C PF14667.1 KZN94539.1 - 0.022 14.5 0.6 0.028 14.1 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Git3 PF11710.3 KZN94539.1 - 0.062 12.8 0.1 0.067 12.7 0.0 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF4131 PF13567.1 KZN94539.1 - 0.069 12.5 1.8 0.07 12.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Anoctamin PF04547.7 KZN94539.1 - 0.33 9.5 3.8 0.41 9.2 2.7 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel PsbX PF06596.6 KZN94539.1 - 1.2 8.8 6.5 0.74 9.5 1.4 2.2 2 1 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) BAR_2 PF10455.4 KZN94540.1 - 4e-62 209.7 1.5 5.5e-62 209.2 1.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KZN94540.1 - 3.2e-19 69.3 6.9 3.5e-18 65.9 4.8 2.0 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 KZN94540.1 - 0.015 15.0 1.0 0.015 15.0 0.7 2.9 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) DUF1795 PF08786.6 KZN94540.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1795) Optomotor-blind PF11078.3 KZN94541.1 - 0.064 13.6 0.1 0.064 13.6 0.0 1.8 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Fungal_trans_2 PF11951.3 KZN94542.1 - 1.2e-19 70.2 0.0 4.8e-14 51.7 0.1 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 KZN94542.1 - 5.1e-07 29.5 9.9 8.9e-07 28.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.10 KZN94543.1 - 2.3e-54 184.3 0.0 8.5e-52 175.9 0.0 2.7 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KZN94543.1 - 7.8e-06 26.2 0.0 4.5e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KZN94543.1 - 0.076 13.3 0.0 2.6 8.4 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Totivirus_coat PF05518.6 KZN94543.1 - 3 5.5 16.1 5 4.8 11.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Proteasome PF00227.21 KZN94544.1 - 1.4e-57 194.0 0.1 1.8e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KZN94544.1 - 7.4e-10 37.9 0.4 1.8e-09 36.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 KZN94545.1 - 2.4e-134 448.6 2.2 3e-134 448.3 1.5 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Methyltransf_23 PF13489.1 KZN94547.1 - 4.8e-13 49.1 0.0 7.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KZN94547.1 - 2.1e-10 40.9 0.0 8.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KZN94547.1 - 6.3e-08 33.0 0.0 3.2e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KZN94547.1 - 3.3e-06 26.7 0.0 0.038 13.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.12 KZN94547.1 - 1.3e-05 24.3 0.0 8.5e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KZN94547.1 - 3.4e-05 24.1 0.0 0.00019 21.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KZN94547.1 - 5.9e-05 23.6 0.0 0.0012 19.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KZN94547.1 - 0.0003 19.2 0.1 0.0022 16.4 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KZN94547.1 - 0.00032 19.8 0.0 0.0017 17.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.6 KZN94547.1 - 0.033 13.6 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KZN94547.1 - 0.06 13.3 0.1 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain KH_1 PF00013.24 KZN94548.1 - 0.0014 18.2 0.0 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KZN94548.1 - 0.02 14.5 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 KH domain GAGA_bind PF06217.7 KZN94548.1 - 0.9 9.4 16.8 1.4 8.8 11.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PDGF_N PF04692.8 KZN94548.1 - 5.5 7.5 12.2 0.42 11.1 4.1 2.4 1 1 2 3 3 3 0 Platelet-derived growth factor, N terminal region Asp-B-Hydro_N PF05279.6 KZN94548.1 - 6.3 6.5 29.5 11 5.7 20.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Band_3_cyto PF07565.8 KZN94548.1 - 6.9 6.1 14.1 12 5.3 9.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATG22 PF11700.3 KZN94549.1 - 3.4e-131 438.0 33.2 3.8e-131 437.8 23.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KZN94549.1 - 3.7e-09 35.7 37.5 2.2e-05 23.3 11.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_transf_90 PF05686.7 KZN94550.1 - 1e-27 96.8 0.1 1.4e-27 96.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KZN94550.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1564 PF07600.6 KZN94550.1 - 0.037 13.3 0.7 0.095 12.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) MU117 PF15474.1 KZN94551.1 - 4.4e-14 52.7 9.2 5.7e-14 52.3 6.4 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family DUF3632 PF12311.3 KZN94552.1 - 7.4e-44 149.7 0.0 9.4e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_17 PF00332.13 KZN94553.1 - 0.008 15.2 0.4 0.016 14.2 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Beta-lactamase PF00144.19 KZN94554.1 - 1.8e-41 142.2 0.0 2.6e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DAP_C PF07932.7 KZN94554.1 - 2.9e-40 136.3 0.1 7.1e-40 135.0 0.1 1.7 1 0 0 1 1 1 1 D-aminopeptidase, domain C DAP_B PF07930.7 KZN94554.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.6 1 0 0 1 1 1 1 D-aminopeptidase, domain B WaaY PF06176.6 KZN94555.1 - 0.0065 15.7 0.0 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF2196 PF09962.4 KZN94556.1 - 3.2e-21 74.8 0.7 5.3e-21 74.1 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2196) Flavoprotein PF02441.14 KZN94557.1 - 1.8e-42 144.0 0.1 2.6e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein adh_short PF00106.20 KZN94558.1 - 8.6e-21 74.5 0.1 1.4e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KZN94558.1 - 2.8e-09 37.1 0.0 4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KZN94558.1 - 2.8e-05 23.8 0.1 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KZN94558.1 - 0.0042 17.1 0.1 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KZN94558.1 - 0.047 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erg28 PF03694.8 KZN94559.1 - 1.6e-36 124.7 0.3 1.9e-36 124.4 0.2 1.0 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 KZN94560.1 - 1.2e-68 230.7 0.5 4.5e-67 225.6 0.2 2.5 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KZN94560.1 - 1.7e-56 190.3 0.1 4.8e-56 188.8 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KZN94560.1 - 0.13 12.8 0.0 0.58 10.7 0.0 2.0 2 1 0 2 2 2 0 HIT domain F-box-like PF12937.2 KZN94561.1 - 1.2e-05 24.8 0.6 3.3e-05 23.5 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KZN94561.1 - 0.00054 19.5 0.9 0.0015 18.0 0.6 1.8 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 KZN94562.1 - 2.1e-42 145.1 47.0 2.1e-42 145.1 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KZN94562.1 - 2.6e-07 29.6 26.8 1.6e-06 27.0 18.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DSBA PF01323.15 KZN94563.1 - 6.8e-20 71.4 0.0 7.6e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain NAD_binding_2 PF03446.10 KZN94564.1 - 1.7e-28 99.4 0.0 2.5e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KZN94564.1 - 5.8e-08 33.0 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KZN94564.1 - 4.4e-07 29.9 0.1 1.2e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KZN94564.1 - 1.3e-05 25.3 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KZN94564.1 - 0.043 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KZN94564.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.9 KZN94564.1 - 0.091 12.1 0.8 0.52 9.6 0.5 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sugar_tr PF00083.19 KZN94565.1 - 2.3e-139 464.8 32.4 2.6e-139 464.7 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN94565.1 - 8.2e-27 93.8 49.8 8.7e-23 80.5 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KZN94565.1 - 0.0033 17.3 1.2 0.016 15.1 0.8 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) NOGCT PF08155.6 KZN94566.1 - 5.4e-27 93.2 3.0 1.2e-26 92.1 2.0 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KZN94566.1 - 2.6e-26 91.2 0.4 5.7e-26 90.1 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KZN94566.1 - 5.1e-15 55.4 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KZN94566.1 - 3.1e-07 29.7 0.0 1e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KZN94566.1 - 0.00066 20.1 0.0 0.0045 17.4 0.0 2.3 1 1 1 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 KZN94566.1 - 0.0068 16.2 0.0 4.7 7.0 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Acetyltransf_1 PF00583.19 KZN94567.1 - 4.1e-12 45.9 0.0 6.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KZN94567.1 - 4.9e-09 36.2 0.0 7.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KZN94567.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KZN94567.1 - 0.00049 20.0 0.1 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KZN94567.1 - 0.0017 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KZN94567.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KZN94567.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF619 PF04768.8 KZN94568.1 - 2.7e-53 179.8 0.0 4e-52 176.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF619) PEP_mutase PF13714.1 KZN94568.1 - 0.053 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase KR PF08659.5 KZN94569.1 - 4.3e-17 62.3 0.0 6.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KZN94569.1 - 2.9e-11 43.5 0.0 5.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KZN94569.1 - 0.0011 19.1 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 KZN94570.1 - 5.2e-07 29.5 0.1 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KZN94570.1 - 1.1e-05 25.4 0.1 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DPM3 PF08285.6 KZN94571.1 - 0.06 13.1 0.1 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GtrA PF04138.9 KZN94571.1 - 1.1 9.2 7.6 0.41 10.6 2.1 2.3 1 1 1 2 2 2 0 GtrA-like protein DUF1218 PF06749.7 KZN94571.1 - 5.4 7.5 7.1 6 7.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) PrgI PF12666.2 KZN94571.1 - 9.3 6.4 8.5 7.1 6.8 0.3 2.8 1 1 0 2 2 2 0 PrgI family protein Sugar_tr PF00083.19 KZN94572.1 - 3.6e-82 276.3 27.2 4e-82 276.1 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KZN94572.1 - 4.8e-19 68.2 21.9 7.4e-19 67.6 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KZN94572.1 - 2 8.4 9.4 0.2 11.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228)