# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RT_RNaseH_2 PF17919.1 CEP06770.1 - 7.6e-29 99.7 0.0 1.7e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP06770.1 - 8.2e-29 100.0 0.0 2e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP06770.1 - 6.3e-13 49.0 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP06770.1 - 3.3e-10 39.9 0.4 6.7e-10 38.9 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP06770.1 - 2.7e-05 24.3 1.2 6.5e-05 23.1 1.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger MukB_hinge PF16330.5 CEP06770.1 - 0.034 13.9 0.5 7.2 6.3 0.1 2.6 2 0 0 2 2 2 0 MukB hinge domain Retrotrans_gag PF03732.17 CEP06771.1 - 0.00016 21.9 0.1 0.00033 20.9 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Oxysterol_BP PF01237.18 CEP06773.1 - 8.6e-72 242.0 0.5 1.4e-69 234.7 0.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein CPL PF08144.11 CEP06774.1 - 1.7e-42 145.2 7.1 1.4e-41 142.2 0.5 4.4 5 2 1 6 6 6 1 CPL (NUC119) domain PUF PF00806.19 CEP06774.1 - 2.6e-07 30.0 1.9 5.1 7.0 0.0 6.6 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat DUF1744 PF08490.12 CEP06775.1 - 6e-137 456.5 0.3 9.2e-137 455.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CEP06775.1 - 1.4e-77 261.2 2.5 1.4e-77 261.2 2.5 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CEP06775.1 - 1.6e-13 50.2 3.7 5.7e-12 45.1 0.8 4.0 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CEP06775.1 - 7.1e-10 38.9 0.3 1.9e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CEP06775.1 - 3.6e-06 27.1 0.1 2.3e-05 24.4 0.1 2.5 1 0 0 1 1 1 1 RNase_H superfamily Cytochrome_C7 PF14522.6 CEP06775.1 - 6.1e-05 22.9 3.3 0.00017 21.5 3.3 1.7 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c DUF4379 PF14311.6 CEP06775.1 - 0.24 11.8 4.6 1.1 9.7 1.1 2.7 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Cytochrom_c3_2 PF14537.6 CEP06775.1 - 3.4 8.2 13.4 0.099 13.1 6.8 1.9 2 0 0 2 2 2 0 Cytochrome c3 DNA_pol_phi PF04931.13 CEP06776.1 - 0.44 8.6 22.5 0.45 8.6 22.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi IFT57 PF10498.9 CEP06776.1 - 5.7 5.8 8.2 6.5 5.6 8.2 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Paf1 PF03985.13 CEP06776.1 - 6.2 5.7 11.3 7.4 5.4 11.3 1.0 1 0 0 1 1 1 0 Paf1 RT_RNaseH_2 PF17919.1 CEP06777.1 - 1.6e-30 105.1 0.0 4.2e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06777.1 - 1.6e-28 99.8 0.0 4.9e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP06777.1 - 7.5e-27 93.7 0.0 1.9e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP06777.1 - 5.3e-18 65.3 0.0 1.3e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP06777.1 - 3.4e-17 62.3 0.1 1.1e-16 60.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Retrotrans_gag PF03732.17 CEP06777.1 - 4.8e-13 49.2 0.0 1.6e-12 47.6 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP06777.1 - 0.0022 18.5 0.0 0.0063 17.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease MLVIN_C PF18697.1 CEP06777.1 - 0.0033 17.5 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP_2 PF08284.11 CEP06777.1 - 0.0073 16.1 0.1 0.041 13.6 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP06777.1 - 0.01 16.5 0.0 0.033 14.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_3 PF13917.6 CEP06777.1 - 0.043 13.8 0.3 0.13 12.2 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP06777.1 - 0.2 11.4 3.3 0.55 10.0 3.3 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger PIF1 PF05970.14 CEP06778.1 - 4.1e-07 29.5 0.2 5.6e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 CEP06778.1 - 0.00041 20.1 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP06778.1 - 0.00055 18.0 0.0 0.00076 17.5 0.0 1.2 1 0 0 1 1 1 1 Helicase Chromo PF00385.24 CEP06779.1 - 5e-09 35.9 0.2 8.4e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KDZ PF18758.1 CEP06782.1 - 8.5e-38 130.2 0.3 1.7e-37 129.2 0.3 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP06782.1 - 3.4e-07 30.4 0.7 8.7e-07 29.1 0.7 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Osteoregulin PF07175.11 CEP06782.1 - 1 9.5 5.0 3.8 7.7 5.0 2.0 1 0 0 1 1 1 0 Osteoregulin Bac_transf PF02397.16 CEP06783.1 - 0.055 13.1 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase VWA_2 PF13519.6 CEP06784.1 - 0.006 17.2 1.7 0.1 13.3 0.2 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain PLDc PF00614.22 CEP06786.1 - 6.7e-18 64.1 2.6 1.4e-10 40.9 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEP06786.1 - 4.4e-14 52.5 0.3 8.2e-06 25.7 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PX PF00787.24 CEP06786.1 - 2e-05 24.5 0.0 7.2e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 PX domain YmzC PF14157.6 CEP06786.1 - 0.051 13.7 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 YmzC-like protein ArfGap PF01412.18 CEP06787.1 - 2.2e-38 130.9 0.1 2.2e-38 130.9 0.1 3.3 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf UBA PF00627.31 CEP06787.1 - 2.2e-06 27.4 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain HOIP-UBA PF16678.5 CEP06787.1 - 3.2e-05 24.0 0.2 0.018 15.1 0.0 2.8 1 1 1 2 2 2 2 HOIP UBA domain pair SR-25 PF10500.9 CEP06787.1 - 0.26 10.9 11.3 0.4 10.2 4.7 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lustrin_cystein PF14625.6 CEP06788.1 - 0.062 13.7 6.0 0.75 10.2 0.6 2.5 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain RVT_1 PF00078.27 CEP06789.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP06789.1 - 0.00096 18.7 0.2 0.0035 16.9 0.2 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP06789.1 - 0.0024 17.7 0.5 0.0086 15.9 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP06790.1 - 8.6e-07 28.8 2.0 1.4e-06 28.1 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEP06790.1 - 9.3e-06 25.8 0.8 2.2e-05 24.6 0.8 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP06790.1 - 3.4e-05 24.3 0.0 8.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP06790.1 - 0.00023 21.8 0.0 0.00066 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 CEP06791.1 - 7.8e-08 32.1 0.1 1.8e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NPV_P10 PF05531.12 CEP06791.1 - 0.081 13.4 0.4 0.28 11.7 0.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Amidase_6 PF12671.7 CEP06791.1 - 0.24 11.5 2.6 0.2 11.8 1.0 1.6 2 0 0 2 2 2 0 Putative amidase domain RVT_1 PF00078.27 CEP06792.1 - 3e-33 115.2 0.0 9.7e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP06793.1 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RNase_H_2 PF13482.6 CEP06793.1 - 0.068 13.2 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 RNase_H superfamily rve_3 PF13683.6 CEP06793.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain PIF1 PF05970.14 CEP06794.1 - 6.3e-59 200.0 0.0 7.2e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Lipase_GDSL_2 PF13472.6 CEP06794.1 - 0.072 13.5 0.2 2.7 8.4 0.0 2.5 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AAA PF00004.29 CEP06795.1 - 2.1e-05 24.9 0.1 0.0002 21.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEP06795.1 - 0.00077 19.4 0.1 0.73 9.7 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 CEP06795.1 - 0.0021 18.3 0.0 0.006 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP06795.1 - 0.0033 17.8 0.0 0.01 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CEP06795.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CEP06795.1 - 0.048 13.7 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CEP06795.1 - 0.06 13.2 0.7 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 CEP06795.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-RVT PF13966.6 CEP06799.1 - 1.9e-06 28.5 1.2 5.6e-06 27.0 1.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase APC_N_CC PF16689.5 CEP06800.1 - 0.043 13.9 3.1 0.099 12.7 3.1 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Bap31_Bap29_C PF18035.1 CEP06800.1 - 0.1 12.6 1.2 0.21 11.6 1.2 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain V_ATPase_I PF01496.19 CEP06800.1 - 0.11 10.5 0.3 0.13 10.2 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L5e PF17144.4 CEP06801.1 - 1.6e-52 177.8 0.0 3.1e-52 176.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CEP06801.1 - 1.2e-27 96.7 2.3 1.6e-27 96.3 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DDE_3 PF13358.6 CEP06802.1 - 1.5e-18 66.9 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 CEP06802.1 - 0.00052 19.7 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease SUIM_assoc PF16619.5 CEP06803.1 - 0.00027 20.9 17.2 0.001 19.1 0.0 3.1 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CEP06803.1 - 0.032 14.2 14.2 0.039 13.9 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CEP06803.1 - 0.12 13.0 6.5 0.19 12.4 6.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CEP06803.1 - 0.18 10.6 2.0 0.22 10.3 2.0 1.2 1 0 0 1 1 1 0 Presenilin PIF1 PF05970.14 CEP06805.1 - 1e-26 94.0 3.4 2.6e-08 33.5 0.0 3.3 1 1 2 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CEP06805.1 - 1.4e-11 44.5 0.0 4.6e-09 36.3 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CEP06805.1 - 0.00032 21.0 0.1 0.13 12.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain DUF2791 PF10923.8 CEP06805.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_16 PF13191.6 CEP06805.1 - 0.003 18.0 0.0 0.0088 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 CEP06805.1 - 0.004 16.4 0.1 0.45 9.6 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Herpes_Helicase PF02689.14 CEP06805.1 - 0.0063 14.5 0.1 1.2 7.0 0.0 2.1 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.18 CEP06805.1 - 0.0098 15.7 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 CEP06805.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AFG1_ATPase PF03969.16 CEP06805.1 - 0.052 12.4 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase KAP_NTPase PF07693.14 CEP06805.1 - 0.11 11.7 0.0 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain DNA_pol_A_exo1 PF01612.20 CEP06806.1 - 1.3e-16 60.9 0.0 2.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF5549 PF17703.1 CEP06808.1 - 0.18 11.4 1.6 0.32 10.6 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Raf1_HTH PF18579.1 CEP06809.1 - 0.089 12.5 0.1 0.24 11.1 0.1 1.7 1 1 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain DUF1836 PF08876.11 CEP06810.1 - 0.035 14.2 0.3 0.053 13.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) EF-hand_8 PF13833.6 CEP06811.1 - 0.0068 16.2 1.8 0.028 14.2 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CEP06811.1 - 0.012 15.1 0.0 0.035 13.6 0.0 1.9 1 0 0 1 1 1 0 EF hand TetR_C_10 PF16295.5 CEP06811.1 - 0.041 14.2 0.5 0.081 13.2 0.5 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain EF-hand_1 PF00036.32 CEP06811.1 - 0.18 11.5 0.1 0.18 11.5 0.1 3.4 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 CEP06811.1 - 0.22 12.0 13.0 0.76 10.3 0.1 4.5 4 1 0 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 CEP06811.1 - 0.43 10.6 0.1 0.43 10.6 0.1 4.0 5 0 0 5 5 5 0 EF-hand domain Lipl32 PF12103.8 CEP06811.1 - 7.4 6.2 8.8 2.2 7.9 0.1 2.8 2 1 1 3 3 3 0 Surface lipoprotein of Spirochaetales order USP7_ICP0_bdg PF12436.8 CEP06812.1 - 3.4e-64 216.5 4.0 1.5e-62 211.1 0.9 2.8 3 0 0 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CEP06812.1 - 2.8e-56 190.5 6.2 1.1e-55 188.5 1.0 3.4 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CEP06812.1 - 4e-50 170.7 0.1 6.7e-50 170.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP06812.1 - 1.7e-20 73.9 0.0 6.3e-20 72.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CEP06812.1 - 4.9e-08 33.1 0.1 1.8e-07 31.3 0.1 2.1 1 0 0 1 1 1 1 MATH domain DUF2073 PF09846.9 CEP06812.1 - 0.13 12.2 0.0 1.9 8.4 0.0 2.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2073) NeA_P2 PF12312.8 CEP06812.1 - 0.25 10.8 1.2 0.66 9.4 1.2 1.6 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein GrpE PF01025.19 CEP06813.1 - 0.017 14.8 2.6 0.02 14.5 2.6 1.0 1 0 0 1 1 1 0 GrpE P4Ha_N PF08336.11 CEP06813.1 - 0.025 14.6 1.1 0.03 14.3 1.1 1.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Spectrin PF00435.21 CEP06813.1 - 0.026 15.0 0.8 0.033 14.7 0.8 1.2 1 0 0 1 1 1 0 Spectrin repeat Herpes_BLRF2 PF05812.12 CEP06813.1 - 0.028 14.5 2.6 0.057 13.5 1.2 1.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Myb_DNA-bind_5 PF13873.6 CEP06813.1 - 0.032 14.3 1.1 0.041 14.0 1.1 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF4337 PF14235.6 CEP06813.1 - 0.037 14.1 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SGIII PF15467.6 CEP06813.1 - 0.048 12.9 1.1 0.05 12.9 1.1 1.0 1 0 0 1 1 1 0 Secretogranin-3 Dna2 PF08696.11 CEP06813.1 - 0.061 13.1 0.4 0.071 12.9 0.4 1.0 1 0 0 1 1 1 0 DNA replication factor Dna2 HGAL PF15666.5 CEP06813.1 - 0.071 13.2 0.4 0.083 13.0 0.4 1.1 1 0 0 1 1 1 0 Germinal center-associated lymphoma 4HB_MCP_1 PF12729.7 CEP06813.1 - 0.13 11.8 2.8 0.16 11.5 2.8 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ING PF12998.7 CEP06813.1 - 0.15 12.6 2.1 0.17 12.5 2.1 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YtxH PF12732.7 CEP06813.1 - 3.7 8.1 12.2 0.16 12.5 4.2 2.0 2 0 0 2 2 2 0 YtxH-like protein ORMDL PF04061.14 CEP06814.1 - 3.5e-48 162.9 3.3 5.1e-48 162.3 3.3 1.2 1 0 0 1 1 1 1 ORMDL family Cyclin PF08613.11 CEP06815.1 - 1.9e-09 38.1 0.2 1.9e-09 38.1 0.2 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP06815.1 - 0.0026 17.5 0.9 0.0073 16.0 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Telethonin PF09470.10 CEP06815.1 - 0.091 12.6 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 Telethonin protein Zn_clus PF00172.18 CEP06817.1 - 5.2e-09 36.1 9.1 1.1e-08 35.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LOB PF03195.14 CEP06817.1 - 3 8.5 6.6 29 5.3 0.1 2.8 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain p450 PF00067.22 CEP06818.1 - 1.1e-36 126.7 0.1 3.1e-36 125.1 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 CEP06819.1 - 9.5e-09 35.4 0.1 2e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Transposase DUF1601 PF07671.11 CEP06820.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DDE_3 PF13358.6 CEP06821.1 - 1.6e-23 83.1 0.0 7.7e-22 77.6 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP06821.1 - 0.0076 16.4 0.7 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 CEP06821.1 - 0.013 15.7 0.3 4.1 7.7 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_29 PF13551.6 CEP06821.1 - 0.014 15.4 0.1 0.094 12.7 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix Abhydrolase_1 PF00561.20 CEP06822.1 - 1.7e-18 67.2 0.1 6.1e-17 62.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP06822.1 - 2.5e-13 49.8 0.1 6.5e-13 48.5 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP06822.1 - 1.2e-09 39.1 0.1 1.3e-09 39.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CEP06822.1 - 0.00028 20.6 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 CEP06822.1 - 0.044 13.9 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 CEP06822.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PPR_2 PF13041.6 CEP06823.1 - 1.3e-13 50.9 2.8 5.3e-09 36.1 0.1 3.9 3 1 2 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CEP06823.1 - 3.7e-08 33.3 0.7 1.3e-06 28.4 0.1 2.9 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 CEP06823.1 - 6.6e-08 32.3 0.9 0.02 15.1 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 CEP06823.1 - 0.0002 21.0 0.0 0.011 15.4 0.0 2.9 2 1 0 2 2 2 1 PPR repeat PPR_long PF17177.4 CEP06823.1 - 0.00021 20.7 0.1 0.00047 19.6 0.1 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CEP06823.1 - 0.0051 17.3 2.4 0.87 10.1 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2989 PF11207.8 CEP06823.1 - 0.069 12.9 7.0 1.2 8.8 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2989) Tma16 PF11176.8 CEP06823.1 - 0.091 12.6 1.2 0.54 10.1 0.2 2.4 2 0 0 2 2 2 0 Translation machinery-associated protein 16 RNA_pol_Rpb5_C PF01191.19 CEP06824.1 - 4.5e-35 119.3 0.3 1.1e-34 118.1 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CEP06824.1 - 1.7e-30 105.4 0.0 3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CEP06824.1 - 0.032 14.2 0.0 0.18 11.9 0.0 2.1 2 1 1 3 3 3 0 Restriction endonuclease Phosphodiest PF01663.22 CEP06825.1 - 3e-12 46.8 0.1 4.7e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CEP06825.1 - 0.0035 16.8 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CEP06825.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily MBOAT_2 PF13813.6 CEP06826.1 - 8.5e-08 32.4 1.0 8.5e-08 32.4 1.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Alpha_E1_glycop PF01589.16 CEP06826.1 - 0.066 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein PH PF00169.29 CEP06827.1 - 0.0061 17.0 0.0 0.028 14.9 0.0 2.2 1 0 0 1 1 1 1 PH domain ALMT PF11744.8 CEP06827.1 - 0.026 13.4 3.1 0.054 12.3 3.1 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Thioredoxin_8 PF13905.6 CEP06827.1 - 2.1 8.7 6.6 0.77 10.1 0.2 3.3 5 0 0 5 5 5 0 Thioredoxin-like NAD_binding_6 PF08030.12 CEP06828.1 - 2.5e-16 60.2 0.0 8.6e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CEP06828.1 - 1.1e-14 54.6 6.8 1.1e-14 54.6 6.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CEP06828.1 - 7.5e-13 48.5 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 CEP06828.1 - 0.0045 17.3 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain BBL5 PF07289.11 CEP06828.1 - 0.088 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Period_C PF12114.8 CEP06829.1 - 4.9 6.7 7.0 1.7 8.2 4.3 1.6 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF515 PF04415.12 CEP06829.1 - 5.5 5.3 5.2 4.8 5.5 3.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Sec23_trunk PF04811.15 CEP06830.1 - 1.2e-77 260.8 0.0 1.7e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CEP06830.1 - 2.9e-31 108.0 0.4 5.5e-31 107.2 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CEP06830.1 - 3.6e-24 84.5 0.1 8.1e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEP06830.1 - 1e-16 60.6 5.3 2e-16 59.7 5.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEP06830.1 - 1.1e-14 54.1 0.0 3.5e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat TMEM70 PF06979.12 CEP06831.1 - 5.1e-05 23.7 0.3 0.0001 22.7 0.1 1.6 2 0 0 2 2 2 1 Assembly, mitochondrial proton-transport ATP synth complex Pkinase PF00069.25 CEP06832.1 - 1.3e-53 182.1 0.0 2.1e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP06832.1 - 2.1e-20 73.1 0.0 3.9e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP06832.1 - 8.1e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP06832.1 - 0.00012 21.0 0.6 0.00042 19.2 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEP06832.1 - 0.00053 19.4 0.1 0.00098 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myc_N PF01056.18 CEP06832.1 - 0.004 17.1 1.6 0.009 15.9 1.6 1.6 1 0 0 1 1 1 1 Myc amino-terminal region APH PF01636.23 CEP06832.1 - 0.16 11.9 0.7 0.51 10.2 0.4 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Caps_synth PF05704.12 CEP06834.1 - 0.043 13.2 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DDE_3 PF13358.6 CEP06835.1 - 8.2e-29 100.2 0.1 3.2e-26 91.9 0.1 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.23 CEP06837.1 - 0.0039 17.2 4.5 0.0039 17.2 4.5 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEP06837.1 - 0.013 15.2 2.7 0.028 14.1 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CHY PF05495.12 CEP06837.1 - 0.043 14.3 4.5 0.1 13.1 4.5 1.6 1 0 0 1 1 1 0 CHY zinc finger PPP4R2 PF09184.11 CEP06837.1 - 0.053 13.1 7.9 0.065 12.8 7.9 1.1 1 0 0 1 1 1 0 PPP4R2 CBFB_NFYA PF02045.15 CEP06840.1 - 8.6e-30 103.1 5.4 2.7e-29 101.6 5.4 1.9 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Pex14_N PF04695.13 CEP06840.1 - 1.7 9.3 17.6 0.46 11.1 6.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RA PF00788.23 CEP06841.1 - 2.9e-07 31.0 0.1 2.9e-07 31.0 0.1 3.2 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Spt20 PF12090.8 CEP06841.1 - 0.0021 17.7 25.9 0.0021 17.7 25.9 2.0 2 0 0 2 2 2 1 Spt20 family PH PF00169.29 CEP06841.1 - 0.018 15.5 0.0 0.087 13.3 0.0 2.3 1 0 0 1 1 1 0 PH domain PepSY_TM PF03929.16 CEP06841.1 - 0.098 12.3 3.1 0.26 10.9 3.1 1.7 1 0 0 1 1 1 0 PepSY-associated TM region EIIBC-GUT_N PF03612.14 CEP06841.1 - 0.16 11.7 8.0 0.38 10.5 8.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Androgen_recep PF02166.16 CEP06841.1 - 0.22 10.3 22.7 0.44 9.3 22.7 1.5 1 0 0 1 1 1 0 Androgen receptor Rsc14 PF08586.10 CEP06841.1 - 3 8.7 10.0 5.7 7.8 8.3 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Pannexin_like PF12534.8 CEP06841.1 - 6.5 5.7 10.0 17 4.4 10.0 1.8 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Connexin PF00029.19 CEP06841.1 - 8.7 6.0 8.8 21 4.8 8.8 1.7 1 0 0 1 1 1 0 Connexin DDT PF02791.17 CEP06842.1 - 0.11 12.9 0.0 5.9 7.3 0.0 2.1 2 0 0 2 2 2 0 DDT domain DUF1631 PF07793.11 CEP06843.1 - 0.0061 15.0 0.4 0.0073 14.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Sld5 PF05916.11 CEP06843.1 - 0.03 14.8 0.9 0.058 13.9 0.9 1.5 1 1 0 1 1 1 0 GINS complex protein TMEM237 PF15383.6 CEP06843.1 - 0.095 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 B3_4 PF03483.17 CEP06843.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.4 1 1 0 1 1 1 0 B3/4 domain Fimbrial_PilY2 PF14481.6 CEP06845.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Zmiz1_N PF18028.1 CEP06846.1 - 3.1e-10 40.3 0.1 4.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain LINES_C PF14695.6 CEP06847.1 - 0.00015 21.1 0.3 0.00042 19.7 0.3 1.8 1 0 0 1 1 1 1 Lines C-terminus F-box PF00646.33 CEP06848.1 - 0.003 17.4 0.8 0.003 17.4 0.8 1.9 2 0 0 2 2 2 1 F-box domain RT_RNaseH PF17917.1 CEP06849.1 - 3.4e-26 91.6 0.0 4.9e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP06849.1 - 2.3e-18 66.1 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Gal4_dimer PF03902.13 CEP06849.1 - 0.05 13.8 0.5 0.1 12.8 0.5 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Asp_protease PF09668.10 CEP06850.1 - 1.2e-09 38.1 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP06850.1 - 7.5e-08 32.8 0.0 1.7e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP06850.1 - 5.3e-07 30.2 0.0 1.5e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP06850.1 - 0.0062 16.3 0.2 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Cwf_Cwc_15 PF04889.12 CEP06850.1 - 0.069 12.9 8.0 0.11 12.2 8.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox_2 PF07992.14 CEP06851.1 - 1.1e-19 70.7 0.2 3.4e-13 49.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP06851.1 - 0.00062 19.8 0.1 1.9 8.5 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CEP06851.1 - 0.0015 17.8 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 CEP06851.1 - 0.0021 16.8 0.0 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CEP06851.1 - 0.0027 18.3 0.3 0.16 12.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP06851.1 - 0.0038 16.5 1.6 2.2 7.5 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEP06851.1 - 0.04 13.0 0.0 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 CEP06851.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP06851.1 - 0.053 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CEP06851.1 - 0.2 10.7 0.1 0.57 9.2 0.1 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 CEP06851.1 - 0.54 9.8 2.2 12 5.4 0.8 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase C2 PF00168.30 CEP06852.1 - 3.8e-21 75.3 4.0 1.6e-09 38.0 0.3 3.1 3 0 0 3 3 3 2 C2 domain Pet20 PF08692.10 CEP06852.1 - 2.9 8.6 9.4 7 7.4 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial protein Pet20 4HBT PF03061.22 CEP06853.1 - 0.0058 17.0 0.0 0.23 11.9 0.0 2.5 2 0 0 2 2 2 1 Thioesterase superfamily RT_RNaseH_2 PF17919.1 CEP06855.1 - 1e-27 96.0 0.0 2.4e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP06855.1 - 3.9e-26 91.4 0.0 8.3e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06855.1 - 6.4e-12 45.5 0.9 2.1e-11 43.7 0.9 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP06855.1 - 2.4e-10 40.3 0.6 7.9e-10 38.7 0.6 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP06855.1 - 0.0039 17.4 2.3 0.0092 16.2 1.7 2.1 2 0 0 2 2 2 1 H2C2 zinc finger DUF4286 PF14114.6 CEP06855.1 - 0.022 15.2 0.1 0.082 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF3884 PF13024.6 CEP06855.1 - 0.029 13.9 0.0 0.095 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) GAGA_bind PF06217.12 CEP06855.1 - 4 7.6 7.7 2.7 8.2 0.0 2.7 3 0 0 3 3 3 0 GAGA binding protein-like family rve PF00665.26 CEP06856.1 - 3.4e-15 56.3 0.0 1.8e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP06856.1 - 0.00023 21.2 0.7 0.00046 20.2 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 CEP06856.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve_3 PF13683.6 CEP06856.1 - 0.11 12.3 0.3 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 CEP06857.1 - 7.4e-28 96.5 0.1 1.9e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06857.1 - 8.4e-25 87.6 0.1 4.4e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP06857.1 - 5.7e-24 84.4 0.0 2e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CEP06857.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP06857.1 - 2e-06 28.3 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CEP06857.1 - 0.0026 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease JUPITER PF17054.5 CEP06857.1 - 0.18 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter PAPA-1 PF04795.12 CEP06858.1 - 0.15 12.9 4.4 0.23 12.3 4.2 1.6 1 1 0 1 1 1 0 PAPA-1-like conserved region Rap_GAP PF02145.15 CEP06859.1 - 1.7e-24 86.4 0.0 4.3e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Myosin_head PF00063.21 CEP06860.1 - 1.5e-266 886.0 1.7 1.5e-266 886.0 1.7 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CEP06860.1 - 4e-26 91.3 3.7 4e-26 91.3 3.7 3.2 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 CEP06860.1 - 1.4e-13 49.3 23.8 0.00016 21.2 0.4 6.0 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_16 PF13191.6 CEP06860.1 - 0.014 15.8 0.0 0.014 15.8 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain CbiA PF01656.23 CEP06860.1 - 0.017 15.1 0.1 0.063 13.3 0.1 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CEP06860.1 - 0.073 13.3 0.0 0.41 10.9 0.0 2.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEP06860.1 - 0.086 12.5 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Myosin_N PF02736.19 CEP06860.1 - 0.2 11.5 6.5 0.051 13.4 1.8 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Sec7 PF01369.20 CEP06861.1 - 5.5e-50 169.6 0.4 3.3e-49 167.1 0.4 2.0 1 1 0 1 1 1 1 Sec7 domain PH PF00169.29 CEP06861.1 - 0.00015 22.2 0.1 0.088 13.3 0.1 2.8 2 0 0 2 2 2 2 PH domain PH_10 PF15411.6 CEP06861.1 - 0.00094 19.4 0.0 0.00094 19.4 0.0 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH_13 PF16652.5 CEP06861.1 - 0.046 13.5 3.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 CEP06861.1 - 0.049 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 PH domain DPBB_1 PF03330.18 CEP06862.1 - 0.00029 21.0 0.1 0.00065 19.9 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP06862.1 - 0.033 14.0 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 Barwin family NIR_SIR PF01077.22 CEP06863.1 - 7.1e-51 171.9 0.1 2.4e-45 153.9 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 CEP06863.1 - 5e-32 111.1 0.1 1.8e-31 109.3 0.1 2.1 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 CEP06863.1 - 4.7e-27 93.6 0.0 5.8e-14 51.7 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 CEP06863.1 - 6.3e-20 71.9 2.0 6.3e-20 71.9 2.0 2.5 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 CEP06863.1 - 4e-09 36.7 0.0 2e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Flavodoxin_5 PF12724.7 CEP06863.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Pilus_CpaD PF09476.10 CEP06863.1 - 0.055 13.2 0.1 0.055 13.2 0.1 2.2 3 0 0 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) ANAPC_CDC26 PF10471.9 CEP06863.1 - 0.087 13.7 13.3 0.25 12.2 13.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CEP06863.1 - 3.3 7.3 13.3 5.7 6.5 13.3 1.3 1 0 0 1 1 1 0 Spt20 family IL2 PF00715.17 CEP06864.1 - 0.092 12.7 3.7 0.23 11.4 0.1 2.7 3 0 0 3 3 3 0 Interleukin 2 ProQ PF04352.13 CEP06866.1 - 0.08 12.8 0.6 0.64 9.9 0.1 2.0 2 0 0 2 2 2 0 ProQ/FINO family TraD_N PF12615.8 CEP06867.1 - 0.047 14.4 0.0 0.064 14.0 0.0 1.2 1 0 0 1 1 1 0 F sex factor protein N terminal Pectate_lyase_3 PF12708.7 CEP06868.1 - 0.00022 21.2 6.2 0.0056 16.5 5.8 3.1 1 1 0 1 1 1 1 Pectate lyase superfamily protein NosD PF05048.13 CEP06868.1 - 0.00045 19.6 9.0 0.29 10.4 0.1 2.6 2 1 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 CEP06868.1 - 0.0015 18.4 13.4 0.94 9.3 13.4 2.9 1 1 0 1 1 1 1 Right handed beta helix region Ku PF02735.16 CEP06869.1 - 1e-42 146.2 0.0 1.7e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CEP06869.1 - 1.6e-37 129.4 1.7 2.3e-37 128.9 1.7 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CEP06869.1 - 2.9e-05 24.7 0.7 8.8e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Arrestin_N PF00339.29 CEP06870.1 - 7.1e-17 61.8 0.0 1.7e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP06870.1 - 3.8e-06 27.4 0.0 7.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 CEP06870.1 - 0.00027 20.7 0.0 0.0014 18.3 0.0 2.1 2 1 0 2 2 2 1 Arrestin_N terminal like Rgp1 PF08737.10 CEP06870.1 - 0.00036 19.8 0.9 0.00066 19.0 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Pkinase PF00069.25 CEP06871.1 - 2.1e-73 247.0 0.0 6.7e-73 245.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP06871.1 - 1.6e-38 132.5 0.0 3.6e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP06871.1 - 6e-11 42.2 0.0 4.3e-10 39.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEP06871.1 - 2.9e-05 23.2 0.1 6.4e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP06871.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF764 PF05561.11 CEP06871.1 - 0.033 14.0 0.3 0.066 13.0 0.3 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) APH PF01636.23 CEP06871.1 - 0.051 13.5 0.6 0.088 12.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEP06871.1 - 0.16 11.6 1.2 0.25 10.9 0.2 1.9 2 0 0 2 2 2 0 RIO1 family PIP5K PF01504.18 CEP06872.1 - 3.2e-19 69.2 7.2 3.9e-11 42.7 0.2 2.6 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase RasGEF PF00617.19 CEP06873.1 - 1.7e-59 201.0 0.3 4.6e-59 199.6 0.3 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP06873.1 - 5.5e-23 81.2 2.0 4e-22 78.4 2.0 2.5 1 1 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CEP06873.1 - 2.6e-14 52.5 0.2 7.6e-14 51.1 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP06873.1 - 5.8e-11 42.1 0.5 1.1e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CEP06873.1 - 1.2e-10 40.9 0.1 2.4e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CEP06873.1 - 1e-06 28.7 7.9 0.0013 18.8 4.8 2.7 2 0 0 2 2 2 2 WW domain I_LWEQ PF01608.17 CEP06873.1 - 5.3 7.3 9.9 15 5.8 1.6 3.1 1 1 1 2 2 2 0 I/LWEQ domain p450 PF00067.22 CEP06874.1 - 1e-81 275.0 0.0 1.2e-81 274.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 CEP06875.1 - 3.4e-18 65.2 0.0 2.5e-08 33.6 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP06875.1 - 0.00012 21.8 0.0 11 6.0 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CEP06875.1 - 0.0045 17.1 0.0 0.59 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif NID PF07292.13 CEP06875.1 - 0.076 13.7 0.0 0.59 10.8 0.0 2.4 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) DUF4439 PF14530.6 CEP06876.1 - 0.0018 18.9 0.6 0.0026 18.5 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) Ribosomal_L20 PF00453.18 CEP06877.1 - 0.02 15.0 0.9 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L20 Exo_endo_phos_2 PF14529.6 CEP06878.1 - 1.8e-11 43.9 0.9 6.8e-09 35.6 0.1 3.1 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CEP06878.1 - 8.8e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP06878.1 - 0.00049 19.7 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Diedel PF13164.6 CEP06878.1 - 0.023 15.2 0.1 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Diedel PAM2 PF07145.15 CEP06878.1 - 9.3 6.2 6.8 0.75 9.6 0.6 2.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Cas9-BH PF16593.5 CEP06879.1 - 9.3 6.1 8.4 0.35 10.6 0.5 2.4 2 1 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 RabGAP-TBC PF00566.18 CEP06884.1 - 4.5e-08 33.0 0.0 5.6e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SURF1 PF02104.15 CEP06885.1 - 5.8e-41 140.7 0.0 7.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family RRM_1 PF00076.22 CEP06886.1 - 1.2e-21 76.3 0.3 2.2e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP06886.1 - 0.06 13.5 0.2 0.4 10.8 0.0 2.4 2 1 0 2 2 2 0 RNA recognition motif NifU_N PF01592.16 CEP06889.1 - 1.1e-54 184.0 0.1 1.2e-54 183.8 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Cyclin_N PF00134.23 CEP06890.1 - 5e-10 39.2 0.0 5.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP06890.1 - 6.7e-06 26.6 0.1 1.1e-05 25.9 0.1 1.5 1 1 0 1 1 1 1 Cyclin WD40 PF00400.32 CEP06891.1 - 3.5e-12 46.6 2.8 0.012 16.5 0.9 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP06891.1 - 8.1e-07 29.3 0.1 3.9 7.8 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PTP2 PF17022.5 CEP06891.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Polar tube protein 2 from Microsporidia P2 PF07194.11 CEP06891.1 - 0.13 12.3 0.1 3 8.0 0.0 2.7 3 0 0 3 3 3 0 P2 response regulator binding domain S10_plectin PF03501.15 CEP06892.1 - 6e-44 148.0 0.1 7.2e-44 147.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 CEP06892.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Kinase-like PF14531.6 CEP06892.1 - 0.22 10.8 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like XPA_C PF05181.12 CEP06893.1 - 5.9e-25 87.0 1.7 1.6e-24 85.6 1.7 1.8 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CEP06893.1 - 0.13 12.3 3.5 0.3 11.2 3.5 1.6 1 0 0 1 1 1 0 XPA protein N-terminal zf-C3HC4_3 PF13920.6 CEP06893.1 - 0.16 11.8 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_16 PF10294.9 CEP06894.1 - 2.2e-06 27.5 0.0 1.2e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CEP06894.1 - 0.00049 19.9 0.0 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF2722 PF10846.8 CEP06894.1 - 0.059 12.3 0.8 0.083 11.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Methyltransf_23 PF13489.6 CEP06894.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DNA_pol_phi PF04931.13 CEP06894.1 - 0.6 8.1 7.5 1 7.4 7.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 CEP06894.1 - 4.8 7.2 10.0 0.2 11.6 2.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CRCB PF02537.15 CEP06895.1 - 3.3e-29 101.1 12.8 6.2e-16 58.5 4.5 2.2 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Acetyltransf_4 PF13420.7 CEP06896.1 - 1.4e-24 87.0 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEP06896.1 - 2.4e-12 47.7 0.0 3.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP06896.1 - 6.8e-12 45.7 0.0 8.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP06896.1 - 2.1e-06 28.1 0.0 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP06896.1 - 2.2e-06 27.6 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP06896.1 - 1.4e-05 25.0 0.1 2.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_16 PF05301.11 CEP06896.1 - 0.02 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_9 PF13527.7 CEP06896.1 - 0.036 14.2 0.0 0.55 10.3 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP06896.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short_C2 PF13561.6 CEP06897.1 - 8.8e-47 159.6 0.4 1e-46 159.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP06897.1 - 2.3e-28 99.0 0.1 9.6e-28 97.0 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP06897.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Dickkopf_N PF04706.12 CEP06898.1 - 0.007 16.8 9.2 0.007 16.8 9.2 1.7 2 0 0 2 2 2 1 Dickkopf N-terminal cysteine-rich region EB PF01683.18 CEP06898.1 - 2.2 8.7 19.1 0.13 12.6 9.5 2.8 2 1 1 3 3 3 0 EB module TSGP1 PF07771.11 CEP06899.1 - 0.06 13.5 1.6 0.11 12.6 1.6 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 FeoB_associated PF12669.7 CEP06899.1 - 0.089 13.2 0.1 0.089 13.2 0.1 2.7 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein TisB_toxin PF13939.6 CEP06899.1 - 2 8.3 5.1 3.5 7.5 5.1 1.3 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system DUF1992 PF09350.10 CEP06900.1 - 4.1e-24 84.5 0.5 1.4e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Vma12 PF11712.8 CEP06900.1 - 0.21 11.7 3.4 0.61 10.1 3.4 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RD3 PF14473.6 CEP06900.1 - 0.26 11.1 5.1 3.9 7.3 1.5 2.5 2 0 0 2 2 2 0 RD3 protein Pet100 PF09803.9 CEP06900.1 - 4.1 8.0 7.5 18 5.9 1.7 3.2 3 0 0 3 3 3 0 Pet100 Mito_carr PF00153.27 CEP06901.1 - 5.2e-23 80.8 2.2 8.2e-16 57.7 0.0 3.7 4 0 0 4 4 4 2 Mitochondrial carrier protein Voltage_CLC PF00654.20 CEP06902.1 - 1.2e-87 294.5 29.9 3.4e-87 293.0 28.3 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CEP06902.1 - 3.8e-11 43.2 0.1 6e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain Phage_holin_3_1 PF05106.12 CEP06902.1 - 5.2 7.6 9.2 17 5.9 2.1 4.2 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) TFIIE-A_C PF11521.8 CEP06903.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.4 3 1 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Phostensin_N PF13916.6 CEP06903.1 - 5.6 7.4 9.4 0.12 12.7 0.9 2.6 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal RNB PF00773.19 CEP06904.1 - 6.5e-47 160.5 0.0 2.5e-46 158.5 0.0 2.0 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEP06904.1 - 2.5e-18 65.9 0.1 1.4e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CEP06904.1 - 9.9e-06 25.3 0.0 9.9e-06 25.3 0.0 2.5 3 0 0 3 3 3 1 Rrp44-like cold shock domain HGTP_anticodon2 PF12745.7 CEP06904.1 - 0.44 10.0 12.0 1.2 8.5 12.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Filament_head PF04732.14 CEP06905.1 - 0.07 14.0 7.1 0.64 10.9 7.1 2.4 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region Borrelia_P83 PF05262.11 CEP06905.1 - 0.62 8.5 27.3 1.1 7.7 27.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein U79_P34 PF03064.16 CEP06905.1 - 7.4 5.8 13.9 15 4.9 13.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 F-box-like PF12937.7 CEP06906.1 - 0.00035 20.4 0.9 0.0013 18.6 0.9 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP06906.1 - 0.57 10.1 3.3 4.2 7.4 3.3 2.5 1 1 0 1 1 1 0 F-box domain ICMT PF04140.14 CEP06907.1 - 5.7e-23 81.1 1.3 1.3e-22 80.0 1.3 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CEP06907.1 - 8.1e-10 39.0 2.0 1.5e-09 38.2 0.3 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CEP06907.1 - 0.00045 19.8 7.0 0.00094 18.8 7.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Ist1 PF03398.14 CEP06908.1 - 4.6e-56 189.3 0.7 9.5e-56 188.2 0.7 1.6 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway MMR_HSR1_Xtn PF16897.5 CEP06908.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FANCI_S2 PF14676.6 CEP06908.1 - 0.05 13.9 0.7 0.2 12.0 0.0 2.3 3 0 0 3 3 3 0 FANCI solenoid 2 UPF0220 PF05255.11 CEP06909.1 - 1.4e-40 138.6 0.0 2.4e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) zf-RING_4 PF14570.6 CEP06909.1 - 5.4e-18 64.5 6.3 1e-17 63.6 6.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CEP06909.1 - 0.00012 21.9 5.9 0.00024 20.9 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP06909.1 - 0.00027 20.7 4.9 0.00055 19.8 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 CEP06909.1 - 0.00075 19.3 0.1 0.013 15.3 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2243 PF10002.9 CEP06909.1 - 0.0017 18.5 0.5 0.0034 17.5 0.5 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) Nup35_RRM_2 PF14605.6 CEP06909.1 - 0.018 15.0 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.6 CEP06909.1 - 0.026 14.6 1.6 0.07 13.2 1.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 CEP06909.1 - 0.035 14.1 1.3 0.07 13.1 1.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM PF05172.13 CEP06909.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rrn6 PF10214.9 CEP06909.1 - 0.45 8.9 14.0 0.98 7.8 11.5 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-RING_2 PF13639.6 CEP06909.1 - 0.45 10.9 7.1 0.8 10.1 7.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CEP06909.1 - 1.4 8.9 5.3 2.8 7.9 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP06909.1 - 1.6 8.6 5.9 3.1 7.7 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vfa1 PF08432.10 CEP06909.1 - 1.7 9.0 12.8 0.43 10.9 2.5 3.0 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Ndc1_Nup PF09531.10 CEP06909.1 - 2.2 6.9 5.3 3 6.4 5.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S49_N PF08496.10 CEP06909.1 - 8.6 6.4 11.3 19 5.3 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cwf_Cwc_15 PF04889.12 CEP06909.1 - 9.3 5.9 27.6 7 6.3 0.8 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SWIM PF04434.17 CEP06910.1 - 0.00045 19.8 0.3 0.00097 18.7 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger DUF2973 PF11189.8 CEP06911.1 - 0.071 13.2 0.1 0.096 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) CarD_CdnL_TRCF PF02559.16 CEP06911.1 - 0.082 13.6 0.1 0.093 13.5 0.1 1.1 1 0 0 1 1 1 0 CarD-like/TRCF domain XRN_M PF17846.1 CEP06912.1 - 1.3e-150 502.2 0.5 4.4e-149 497.2 0.5 2.1 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CEP06912.1 - 2.1e-101 338.4 0.0 4.2e-101 337.4 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 CEP06912.1 - 0.011 15.7 4.4 0.022 14.8 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP06912.1 - 0.017 15.1 1.6 0.044 13.7 1.6 1.7 1 0 0 1 1 1 0 Zinc knuckle SelP_N PF04592.14 CEP06914.1 - 3.1 7.1 19.0 0.38 10.1 7.5 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4442 PF14539.6 CEP06915.1 - 0.011 15.9 0.0 1.2 9.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4442) DDE_3 PF13358.6 CEP06917.1 - 2.6e-19 69.4 0.0 5e-19 68.5 0.0 1.5 1 1 1 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.19 CEP06917.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF4572 PF15139.6 CEP06917.1 - 0.068 13.1 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) SPO22 PF08631.10 CEP06918.1 - 0.028 13.9 0.1 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like EXS PF03124.14 CEP06919.1 - 4.9e-89 298.9 30.6 6.5e-89 298.5 30.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CEP06919.1 - 1e-33 117.8 22.1 6.6e-21 75.7 5.3 2.6 2 1 1 3 3 3 2 SPX domain NOA36 PF06524.12 CEP06919.1 - 3.9 6.7 7.8 6.6 6.0 7.8 1.2 1 0 0 1 1 1 0 NOA36 protein Complex1_LYR PF05347.15 CEP06920.1 - 0.00079 19.4 1.0 0.00079 19.4 1.0 2.8 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Ribosomal_L30_N PF08079.12 CEP06921.1 - 6.2e-24 84.0 16.6 1.2e-23 83.2 16.6 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CEP06921.1 - 1.8e-17 63.0 1.3 3.4e-17 62.1 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Opi1 PF08618.10 CEP06922.1 - 4e-45 154.8 25.7 7.3e-22 78.2 0.3 4.9 2 1 3 5 5 5 4 Transcription factor Opi1 Perilipin PF03036.16 CEP06922.1 - 9e-07 28.2 0.6 1.2e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 Perilipin family Pex14_N PF04695.13 CEP06922.1 - 0.21 12.2 6.8 0.11 13.1 0.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CCCH PF00642.24 CEP06923.1 - 9.6e-05 22.2 2.9 0.00014 21.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP06923.1 - 1.2 9.3 7.4 2.1 8.5 7.4 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF1640 PF07798.11 CEP06925.1 - 3.3e-44 151.0 9.6 3.5e-44 150.9 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 CEP06925.1 - 0.0017 18.5 4.3 0.017 15.4 4.3 2.5 2 1 0 2 2 2 1 Homeobox associated leucine zipper FapA PF03961.13 CEP06925.1 - 0.0027 16.4 3.6 0.003 16.2 3.6 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 CEP06925.1 - 0.0088 16.4 8.4 0.034 14.5 3.6 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region SRP68 PF16969.5 CEP06925.1 - 0.016 14.2 1.3 0.019 14.0 1.3 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Atg14 PF10186.9 CEP06925.1 - 0.019 14.1 3.7 0.026 13.6 3.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_C PF15908.5 CEP06925.1 - 0.033 14.5 5.0 2.1 8.6 0.0 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal FlaC_arch PF05377.11 CEP06925.1 - 0.093 13.1 6.5 1.1 9.7 1.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mt_ATP-synt_D PF05873.12 CEP06925.1 - 0.095 12.5 5.0 0.25 11.2 0.2 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DDE_Tnp_IS240 PF13610.6 CEP06925.1 - 0.16 12.2 2.6 0.22 11.7 0.7 1.9 1 1 1 2 2 2 0 DDE domain GreA_GreB_N PF03449.15 CEP06925.1 - 0.17 12.0 9.3 0.42 10.8 9.3 1.7 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal Remorin_C PF03763.13 CEP06925.1 - 0.32 10.9 9.0 0.37 10.7 7.5 1.7 1 1 1 2 2 2 0 Remorin, C-terminal region XhlA PF10779.9 CEP06925.1 - 0.39 10.9 7.0 1.2 9.4 0.2 2.4 1 1 1 2 2 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 CEP06925.1 - 0.41 10.7 9.6 0.8 9.8 3.6 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SOGA PF11365.8 CEP06925.1 - 0.46 11.6 9.0 1.5 10.0 9.0 1.9 1 1 0 1 1 1 0 Protein SOGA Erp_C PF06780.11 CEP06925.1 - 0.54 10.3 6.7 1 9.4 5.4 1.8 1 1 1 2 2 2 0 Erp protein C-terminus YabA PF06156.13 CEP06925.1 - 0.95 10.1 8.4 1.8 9.2 5.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 CEP06925.1 - 1.5 9.4 8.9 2.7 8.5 4.7 2.6 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Sec2p PF06428.11 CEP06925.1 - 2.5 8.1 11.7 1.8 8.6 9.6 1.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 CEP06925.1 - 3.5 7.9 9.2 12 6.2 3.8 2.3 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 zf-rbx1 PF12678.7 CEP06926.1 - 8.9e-19 67.5 3.8 1.4e-18 66.9 3.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEP06926.1 - 4.2e-11 42.7 7.9 1.2e-10 41.3 7.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CEP06926.1 - 8.1e-08 32.5 3.9 1.1e-07 32.0 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP06926.1 - 8.6e-06 25.5 1.8 1.5e-05 24.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP06926.1 - 0.00051 19.8 4.2 0.001 18.9 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEP06926.1 - 0.0019 17.9 2.7 0.0034 17.1 2.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 CEP06926.1 - 0.064 13.4 2.1 0.099 12.8 2.1 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CEP06926.1 - 0.086 12.9 2.4 0.15 12.1 2.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CEP06926.1 - 0.26 11.0 6.5 0.6 9.8 6.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CEP06926.1 - 3.9 7.9 7.2 19 5.7 7.2 2.0 1 1 0 1 1 1 0 RING-like domain Asp PF00026.23 CEP06927.1 - 5.5e-42 144.3 4.1 4.3e-21 75.6 0.2 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP06927.1 - 2.2e-09 37.8 6.9 9.5e-06 26.0 0.3 3.2 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal ThiF PF00899.21 CEP06929.1 - 6e-31 107.7 0.0 8.1e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family tRNA_m1G_MT PF01746.21 CEP06930.1 - 1.7e-31 109.5 0.3 2.3e-31 109.0 0.3 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase PRP3 PF08572.10 CEP06930.1 - 0.0072 16.1 3.0 0.0072 16.1 3.0 2.1 2 1 1 3 3 3 1 pre-mRNA processing factor 3 (PRP3) PP2C PF00481.21 CEP06932.1 - 3.6e-52 177.6 0.9 2.1e-51 175.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 CEP06932.1 - 1.7e-40 136.6 58.5 3.7e-09 36.2 5.5 10.1 10 1 1 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 CEP06932.1 - 1.5e-33 114.3 61.7 0.00026 21.3 0.1 13.0 6 3 7 14 14 14 12 Leucine Rich repeats (2 copies) RA PF00788.23 CEP06932.1 - 1.5e-07 31.9 0.2 5.6e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain DUF572 PF04502.13 CEP06932.1 - 0.28 10.8 13.3 0.79 9.3 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) LRR_1 PF00560.33 CEP06932.1 - 0.36 11.6 53.5 4.1 8.3 0.0 14.1 15 2 0 15 15 15 0 Leucine Rich Repeat TFIIA PF03153.13 CEP06932.1 - 2.1 8.3 25.9 0.14 12.1 10.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CEP06932.1 - 5.1 7.3 17.0 1.5 8.9 12.7 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LRR_6 PF13516.6 CEP06932.1 - 7.3 6.9 51.3 3.1 8.1 0.1 12.0 15 0 0 15 15 15 0 Leucine Rich repeat CRM1_C PF08767.11 CEP06933.1 - 3e-06 26.6 2.1 3e-06 26.6 2.1 1.7 2 0 0 2 2 2 1 CRM1 C terminal rve PF00665.26 CEP06934.1 - 2.7e-11 43.7 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP06934.1 - 0.0061 16.3 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DNA_pol_A_exo1 PF01612.20 CEP06935.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease CENP-F_leu_zip PF10473.9 CEP06936.1 - 0.0033 17.5 1.3 0.0033 17.5 1.3 2.4 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 CEP06936.1 - 0.071 13.2 5.8 0.08 13.1 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 CEP06936.1 - 0.15 11.9 2.1 1.1 9.1 1.9 2.5 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 CEP06936.1 - 0.16 12.5 4.2 0.27 11.8 0.1 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-Dof PF02701.15 CEP06936.1 - 0.21 11.7 1.4 0.46 10.7 1.4 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger TRAF_BIRC3_bd PF16673.5 CEP06936.1 - 0.22 11.4 2.4 0.27 11.1 0.3 2.3 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain TMF_TATA_bd PF12325.8 CEP06936.1 - 1.8 8.8 7.9 0.16 12.2 2.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 CEP06936.1 - 2.2 8.4 14.9 0.1 12.7 4.0 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ZapB PF06005.12 CEP06936.1 - 2.4 8.7 7.3 0.3 11.6 1.6 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 CEP06936.1 - 3.6 7.6 13.8 0.076 13.1 4.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 CEP06936.1 - 5.7 7.5 9.1 24 5.5 0.3 2.7 3 0 0 3 3 3 0 Spectrin repeat Exo_endo_phos_2 PF14529.6 CEP06938.1 - 2.2e-08 33.9 0.7 8.1e-08 32.1 0.7 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP06938.1 - 7.5e-07 28.9 0.1 1.3e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CEP06939.1 - 3.3e-65 220.1 0.0 5.7e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP06939.1 - 1.8e-34 119.2 0.0 3.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CEP06939.1 - 1.6e-17 63.1 32.1 3.3e-11 42.9 9.8 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 CEP06939.1 - 1.1e-13 51.0 8.3 3.8e-08 33.3 0.9 2.8 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 CEP06939.1 - 1.3e-09 38.6 0.4 4.3e-09 36.9 0.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CEP06939.1 - 4.3e-05 23.7 0.2 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain C1_2 PF03107.16 CEP06939.1 - 0.099 13.0 21.0 0.031 14.6 7.1 2.6 2 0 0 2 2 2 0 C1 domain Haspin_kinase PF12330.8 CEP06939.1 - 0.13 11.1 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SAGA-Tad1 PF12767.7 CEP06939.1 - 1.7 8.3 5.8 4.5 6.9 5.8 1.7 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.13 CEP06939.1 - 2.6 8.0 20.1 2.4 8.1 15.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos_2 PF14529.6 CEP06941.1 - 3.3e-13 49.5 0.3 4.6e-13 49.1 0.3 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nuc_rec_co-act PF08815.10 CEP06941.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator C1_1 PF00130.22 CEP06942.1 - 5.1e-12 45.5 17.9 1.6e-07 31.1 7.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEP06942.1 - 2.3e-06 27.8 13.7 0.00018 21.8 3.0 2.6 2 0 0 2 2 2 2 C1 domain UNC-79 PF14776.6 CEP06942.1 - 0.00032 19.6 0.0 0.00077 18.3 0.0 1.6 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DEP PF00610.21 CEP06942.1 - 0.03 14.4 0.0 0.081 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PHD PF00628.29 CEP06942.1 - 0.045 13.6 15.3 0.26 11.2 1.2 2.6 2 0 0 2 2 2 0 PHD-finger DGF-1_C PF11040.8 CEP06942.1 - 1.6 8.8 5.0 1 9.4 0.3 2.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus ALMT PF11744.8 CEP06943.1 - 0.16 10.8 1.3 0.24 10.2 1.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ANAPC_CDC26 PF10471.9 CEP06943.1 - 0.16 12.8 11.4 0.052 14.4 4.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF2877 PF11392.8 CEP06943.1 - 0.23 12.2 0.8 0.54 11.0 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2877) EIIBC-GUT_N PF03612.14 CEP06943.1 - 1 9.0 4.0 5.8 6.6 2.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 CEP06943.1 - 1.2 9.9 6.0 4.3 8.1 3.8 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 LRR_6 PF13516.6 CEP06944.1 - 7.3e-19 66.2 13.8 0.13 12.4 0.0 9.2 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 CEP06944.1 - 7.6e-12 45.3 10.5 0.0016 18.8 1.7 6.2 4 1 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP06944.1 - 9.5e-05 22.4 18.0 4.1 8.3 0.2 9.4 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 CEP06944.1 - 0.077 12.8 6.8 3.2 7.6 0.8 4.9 4 2 2 6 6 6 0 Leucine rich repeat SAM_Ste50p PF09235.10 CEP06944.1 - 1.3 9.4 14.5 2.6 8.3 1.0 5.2 4 3 2 6 6 6 0 Ste50p, sterile alpha motif rve PF00665.26 CEP06946.1 - 4.6e-19 68.8 0.0 8.6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP06946.1 - 1.9e-08 34.1 1.6 3.9e-08 33.1 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEP06946.1 - 0.081 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 RVT_1 PF00078.27 CEP06947.1 - 7.3e-29 100.9 0.1 1.2e-28 100.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NST1 PF13945.6 CEP06950.1 - 0.066 13.3 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-RING_11 PF17123.5 CEP06950.1 - 0.1 12.4 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 RING-like zinc finger OrfB_Zn_ribbon PF07282.11 CEP06951.1 - 0.012 15.5 0.0 0.11 12.4 0.0 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain RSB_motif PF16294.5 CEP06952.1 - 1.3e-09 38.2 1.1 1.3e-09 38.2 1.1 3.2 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 CEP06952.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP06952.1 - 0.011 15.7 0.1 0.03 14.4 0.1 1.8 1 0 0 1 1 1 0 RNA binding motif Fibrinogen_BP PF08017.11 CEP06952.1 - 0.013 13.9 4.5 0.019 13.4 4.5 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein Nup35_RRM_2 PF14605.6 CEP06952.1 - 0.069 13.2 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif P53_C PF11619.8 CEP06952.1 - 0.11 12.6 0.4 0.27 11.3 0.4 1.8 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain CH PF00307.31 CEP06953.1 - 1.5e-31 108.8 0.1 1.8e-15 57.1 0.1 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 CEP06953.1 - 1.2e-11 44.5 0.1 4.3e-11 42.8 0.1 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 CEP06953.1 - 3.2e-05 23.7 0.0 0.0013 18.5 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain PLAC9 PF15205.6 CEP06953.1 - 0.84 10.1 4.8 1.1e+02 3.3 0.8 4.5 3 0 0 3 3 3 0 Placenta-specific protein 9 RT_RNaseH_2 PF17919.1 CEP06955.1 - 7.5e-33 112.5 0.1 1.5e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP06955.1 - 3.7e-29 101.1 0.4 7.2e-29 100.2 0.4 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06955.1 - 1.6e-15 57.2 1.3 2.6e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP06955.1 - 9.4e-05 22.9 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP06955.1 - 0.0002 22.0 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP06955.1 - 0.007 16.1 0.2 0.024 14.4 0.1 1.9 1 1 1 2 2 2 1 Retroviral aspartyl protease Peptidase_A17 PF05380.13 CEP06955.1 - 0.06 13.3 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Pao retrotransposon peptidase RA PF00788.23 CEP06957.1 - 3.3e-09 37.3 0.0 0.00023 21.7 0.0 3.2 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CEP06957.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP06957.1 - 0.009 15.8 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ufm1 PF03671.14 CEP06957.1 - 0.04 14.0 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein RSN1_7TM PF02714.15 CEP06958.1 - 2.6e-61 207.3 23.9 2.6e-61 207.3 23.9 2.5 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP06958.1 - 6.9e-35 120.9 0.0 1.8e-34 119.5 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CPSase_L_D2 PF02786.17 CEP06959.1 - 7.4e-78 260.9 0.1 1.4e-77 259.9 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CEP06959.1 - 1.1e-69 234.2 0.0 1.9e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CEP06959.1 - 3e-37 127.5 0.1 7.3e-37 126.3 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP06959.1 - 1.4e-31 108.8 0.0 5.3e-31 106.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CEP06959.1 - 2.4e-30 106.0 0.2 4.1e-30 105.2 0.2 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CEP06959.1 - 4.5e-16 58.4 4.4 2.5e-15 56.1 1.5 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEP06959.1 - 1.4e-09 37.8 0.0 2.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 CEP06959.1 - 4e-07 30.7 1.5 0.041 14.6 0.2 3.7 4 0 0 4 4 3 2 HlyD family secretion protein ATP-grasp PF02222.22 CEP06959.1 - 8.7e-07 28.7 0.1 1.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEP06959.1 - 9.6e-07 28.5 2.5 0.00023 20.9 0.3 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CEP06959.1 - 8.3e-05 22.7 0.0 0.00026 21.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 CEP06959.1 - 0.00023 20.5 0.6 0.042 13.1 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 CEP06959.1 - 0.0014 18.3 0.1 0.0064 16.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain SAC3_GANP PF03399.16 CEP06960.1 - 2.7e-98 329.0 6.7 2.7e-98 329.0 6.7 2.3 2 1 0 2 2 2 1 SAC3/GANP family TFIIA PF03153.13 CEP06960.1 - 0.29 11.1 21.0 0.48 10.4 21.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec63 PF02889.16 CEP06961.1 - 4.6e-175 579.8 0.4 3.4e-95 318.1 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEP06961.1 - 2.4e-49 167.5 0.1 1.3e-26 93.4 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CEP06961.1 - 1e-36 125.5 0.1 4.4e-36 123.4 0.1 2.3 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CEP06961.1 - 5.8e-27 94.8 0.3 3.6e-14 53.1 0.0 3.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP06961.1 - 3.3e-14 53.2 0.0 1.4e-07 31.8 0.0 4.1 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEP06961.1 - 2.2e-06 28.0 0.0 0.025 14.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 CEP06961.1 - 0.0012 18.3 0.0 0.075 12.5 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein RT_RNaseH_2 PF17919.1 CEP06962.1 - 5e-25 87.5 0.0 1.2e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP06962.1 - 1.1e-17 64.3 0.0 2.8e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06962.1 - 7.6e-17 61.6 1.6 7.6e-17 61.6 1.6 3.1 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP06962.1 - 2.1e-15 56.9 0.0 6.9e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP06962.1 - 8.1e-13 48.3 2.6 1.9e-12 47.1 2.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CEP06962.1 - 9.4e-10 38.3 0.2 2.5e-09 36.9 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP06962.1 - 1.6e-05 25.0 1.8 3.5e-05 23.9 1.8 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DUF3949 PF13133.6 CEP06962.1 - 0.16 12.5 0.4 0.6 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) KAsynt_C_assoc PF16197.5 CEP06962.1 - 3.5 8.1 7.1 28 5.2 0.3 3.2 3 1 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension rve PF00665.26 CEP06963.1 - 9.4e-19 67.8 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP06963.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP06963.1 - 0.00084 19.4 0.6 0.0017 18.4 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CEP06964.1 - 3.8e-32 110.7 0.1 1.1e-31 109.2 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP06964.1 - 8.6e-31 105.9 0.7 2.7e-30 104.3 0.2 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06964.1 - 3.5e-19 69.2 0.6 7.9e-19 68.1 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP06964.1 - 1.3e-05 25.8 0.2 3.5e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP06964.1 - 2.8e-05 24.6 1.0 5.2e-05 23.7 0.2 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CEP06964.1 - 0.0065 16.3 0.0 0.095 12.5 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease ArfGap PF01412.18 CEP06964.1 - 0.24 11.5 1.8 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Retrotrans_gag PF03732.17 CEP06964.1 - 0.25 11.7 2.1 23 5.3 0.2 3.2 2 1 1 3 3 3 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 CEP06966.1 - 0.0029 17.8 0.1 0.0062 16.8 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4709 PF15821.5 CEP06966.1 - 0.061 13.6 0.2 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) Exo_endo_phos_2 PF14529.6 CEP06967.1 - 2.7e-06 27.2 0.5 2.7e-06 27.2 0.5 2.8 3 1 0 3 3 3 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP06967.1 - 0.00065 19.7 17.2 0.0017 18.4 3.0 2.7 2 0 0 2 2 2 2 Zinc knuckle Cwf_Cwc_15 PF04889.12 CEP06967.1 - 0.3 10.8 8.3 0.63 9.7 8.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DnaJ_CXXCXGXG PF00684.19 CEP06967.1 - 1.8 9.0 6.9 5.9 7.3 5.9 2.2 2 0 0 2 2 2 0 DnaJ central domain zf-CCHC_4 PF14392.6 CEP06967.1 - 5.8 6.7 5.6 2.1 8.2 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle PHD PF00628.29 CEP06968.1 - 8.9e-06 25.5 17.0 1.4e-05 24.9 11.6 2.6 2 0 0 2 2 2 2 PHD-finger PGA2 PF07543.12 CEP06968.1 - 1.5 8.8 5.0 0.62 10.1 2.0 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 F-box-like PF12937.7 CEP06969.1 - 0.0085 16.0 0.3 0.025 14.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like LAG1-DNAbind PF09271.11 CEP06970.1 - 3.5e-46 157.6 0.2 3.5e-46 157.6 0.2 3.2 4 0 0 4 4 4 1 LAG1, DNA binding BTD PF09270.10 CEP06970.1 - 6.9e-23 81.6 0.1 4.5e-21 75.7 0.1 3.1 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain C12orf66_like PF09404.10 CEP06971.1 - 2.9e-43 148.3 0.1 4e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 KICSTOR complex C12orf66 like Exo70 PF03081.15 CEP06971.1 - 0.018 14.1 0.3 0.027 13.5 0.3 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit DUF3256 PF11644.8 CEP06971.1 - 0.021 14.3 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) DBD_HTH PF18430.1 CEP06972.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain AhpC-TSA PF00578.21 CEP06973.1 - 1.4e-19 70.2 0.0 1.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP06973.1 - 5.3e-07 29.5 0.0 7.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin NUC153 PF08159.12 CEP06974.1 - 3.3e-12 46.0 0.9 6e-12 45.2 0.9 1.4 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CEP06974.1 - 0.00049 20.4 0.0 0.25 11.7 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP06974.1 - 0.11 13.4 0.0 13 6.9 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat NOA36 PF06524.12 CEP06974.1 - 1.9 7.8 10.1 3.5 6.9 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 CEP06974.1 - 3.3 7.8 24.6 7.3 6.6 24.6 1.6 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CEP06974.1 - 9.1 4.4 15.0 13 3.9 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Vint PF14623.6 CEP06975.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Hint-domain Sas10_Utp3 PF04000.15 CEP06975.1 - 0.85 10.3 4.1 22 5.7 0.1 2.9 3 0 0 3 3 3 0 Sas10/Utp3/C1D family DDE_3 PF13358.6 CEP06978.1 - 8.3e-26 90.5 0.2 6.4e-17 61.7 0.0 2.3 1 1 0 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.19 CEP06978.1 - 0.0046 16.6 0.1 0.015 15.0 0.1 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 CEP06979.1 - 2.3e-32 111.0 0.0 1.1e-31 108.8 0.0 2.1 3 0 0 3 3 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP06979.1 - 1.4e-30 105.6 0.0 5e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP06979.1 - 1e-27 97.2 0.0 1.7e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP06979.1 - 1e-14 54.4 0.1 2e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP06979.1 - 1.4e-13 51.1 0.0 3.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 CEP06979.1 - 3.6e-07 30.7 0.0 1.1e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP06979.1 - 2.3e-05 24.9 0.0 5.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Collagen PF01391.18 CEP06979.1 - 0.00021 21.0 5.3 0.00021 21.0 5.3 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) MLVIN_C PF18697.1 CEP06979.1 - 0.0012 18.8 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP_2 PF08284.11 CEP06979.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CEP06979.1 - 0.0049 16.9 0.8 0.012 15.7 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 CEP06979.1 - 0.013 15.3 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain zf-H2C2 PF09337.10 CEP06979.1 - 0.017 15.4 0.0 0.22 11.7 0.0 2.7 3 0 0 3 3 3 0 H2C2 zinc finger rve_3 PF13683.6 CEP06979.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain PhoLip_ATPase_C PF16212.5 CEP06980.1 - 7e-80 268.4 28.6 7e-80 268.4 28.6 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CEP06980.1 - 9.2e-13 49.0 1.5 6.2e-06 26.6 0.1 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP06980.1 - 1.7e-11 44.0 0.0 8.6e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEP06980.1 - 8.8e-09 35.1 0.1 3.1e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP06980.1 - 0.0007 19.4 0.0 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.23 CEP06981.1 - 1.5e-08 34.4 0.0 7.6e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP06981.1 - 7.3e-06 25.8 1.5 0.11 12.4 0.0 2.8 2 1 1 3 3 3 2 Endonuclease-reverse transcriptase Phage_integrase PF00589.22 CEP06982.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CEP06982.1 - 0.0015 18.8 0.1 0.0043 17.3 0.1 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain ErmC PF06308.11 CEP06982.1 - 0.093 13.1 0.5 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 23S rRNA methylastransferase leader peptide (ErmCL) PALP PF00291.25 CEP06983.1 - 5.9e-74 249.1 0.1 7.3e-74 248.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ArAE_2 PF10334.9 CEP06984.1 - 6.5e-17 62.1 0.1 1.8e-16 60.7 0.1 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CEP06984.1 - 5.2e-10 39.0 24.4 1.1e-08 34.6 4.6 3.5 2 1 2 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CEP06984.1 - 5.9e-08 32.9 23.0 5.9e-08 32.9 23.0 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like HAUS4 PF14735.6 CEP06984.1 - 0.26 11.0 4.8 0.14 11.9 1.0 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 ALMT PF11744.8 CEP06984.1 - 7.9 5.2 15.8 0.076 11.8 7.7 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter TPR_11 PF13414.6 CEP06985.1 - 0.07 12.8 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 TPR repeat GST_N_4 PF17172.4 CEP06985.1 - 0.073 13.8 0.2 35 5.2 0.0 3.6 3 0 0 3 3 3 0 Glutathione S-transferase N-terminal domain DDE_3 PF13358.6 CEP06987.1 - 1.4e-22 80.0 0.1 9.3e-16 57.9 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP06987.1 - 0.00032 20.4 0.1 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DUF1804 PF08822.11 CEP06987.1 - 0.0087 16.1 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_32 PF13565.6 CEP06987.1 - 0.02 15.5 0.0 0.049 14.3 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEP06987.1 - 0.078 13.1 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 CEP06987.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family TFIIA PF03153.13 CEP06988.1 - 0.053 13.5 14.6 0.079 12.9 14.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 CEP06988.1 - 0.37 10.2 16.2 0.69 9.3 16.2 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFB6 PF17110.5 CEP06988.1 - 1.8 8.3 9.0 3.8 7.2 9.0 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 CEP06988.1 - 5.7 5.1 21.4 9 4.4 21.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 CEP06988.1 - 7.9 5.8 8.8 13 5.0 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 CEP06988.1 - 8.4 4.5 25.6 11 4.1 25.6 1.1 1 0 0 1 1 1 0 Nop14-like family COG7 PF10191.9 CEP06989.1 - 7.2e-14 51.0 6.3 1.5e-13 50.0 6.3 1.5 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) TPR_1 PF00515.28 CEP06989.1 - 4.5e-08 32.6 5.3 0.00058 19.6 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP06989.1 - 3e-07 30.0 4.8 0.092 12.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 CEP06989.1 - 0.0011 18.8 0.2 0.0025 17.7 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_8 PF13181.6 CEP06989.1 - 0.015 15.5 8.6 0.017 15.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP06989.1 - 0.049 13.9 6.9 0.31 11.4 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat PCI PF01399.27 CEP06990.1 - 2.1e-22 79.6 1.1 2.1e-22 79.6 1.1 3.0 4 0 0 4 4 4 1 PCI domain GCP_N_terminal PF17681.1 CEP06990.1 - 0.00023 20.9 1.5 0.08 12.5 0.8 2.2 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal ACDC PF14733.6 CEP06990.1 - 5.9 7.3 6.9 0.97 9.8 0.4 2.9 3 1 1 4 4 4 0 AP2-coincident C-terminal Vta1 PF04652.16 CEP06991.1 - 4.8e-49 166.1 1.2 6e-49 165.7 0.2 1.6 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CEP06991.1 - 4.8e-14 51.8 3.1 5e-14 51.7 1.2 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain Totivirus_coat PF05518.11 CEP06991.1 - 2.2 6.2 8.1 2.3 6.2 8.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Ndc1_Nup PF09531.10 CEP06991.1 - 3.8 6.1 6.2 4.8 5.7 6.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Forkhead PF00250.18 CEP06992.1 - 1.6e-32 111.6 0.1 3.4e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Peptidase_M41 PF01434.18 CEP06992.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M41 CsbD PF05532.12 CEP06994.1 - 2.6e-11 43.3 3.7 6.9e-11 41.9 3.7 1.7 1 0 0 1 1 1 1 CsbD-like LRR_6 PF13516.6 CEP06994.1 - 1.6e-06 27.7 17.9 0.089 12.9 0.0 8.4 9 0 0 9 9 9 2 Leucine Rich repeat GAT PF03127.14 CEP06994.1 - 0.0028 17.9 0.1 0.015 15.6 0.1 2.3 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 CEP06994.1 - 0.016 15.7 9.2 95 4.2 0.0 7.5 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_4 PF12799.7 CEP06994.1 - 0.025 15.0 14.7 11 6.6 0.6 6.5 3 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Pil1 PF13805.6 CEP06996.1 - 4.1e-38 131.4 4.2 8e-38 130.4 4.2 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Sec34 PF04136.15 CEP06997.1 - 2e-48 164.0 1.3 2e-48 164.0 1.3 2.8 4 0 0 4 4 4 1 Sec34-like family MIT PF04212.18 CEP06997.1 - 0.12 12.4 1.0 14 5.9 0.0 3.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF1690 PF07956.11 CEP06997.1 - 0.41 11.1 3.6 0.52 10.7 0.1 3.0 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DUF3235 PF11574.8 CEP06997.1 - 0.51 11.2 6.1 5.6 7.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3235) DUF21 PF01595.20 CEP06998.1 - 2e-30 105.8 4.8 4.2e-30 104.7 4.8 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CEP06998.1 - 2.6e-05 24.6 0.2 0.22 12.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain Ig_GlcNase PF18368.1 CEP06998.1 - 0.049 13.8 0.1 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain F-box PF00646.33 CEP06999.1 - 6.4e-07 29.1 0.8 1.5e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CEP06999.1 - 2.3e-05 24.2 0.1 9.3e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 CEP06999.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box PTSIIB_sorb PF03830.15 CEP06999.1 - 0.015 15.5 0.0 0.11 12.7 0.0 2.3 3 0 0 3 3 3 0 PTS system sorbose subfamily IIB component DUF3231 PF11553.8 CEP06999.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) VP4_haemagglut PF00426.18 CEP06999.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain F-box_4 PF15966.5 CEP06999.1 - 0.058 13.3 0.2 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 F-box Lactamase_B_3 PF13483.6 CEP06999.1 - 0.12 12.2 0.0 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase superfamily domain V_ATPase_I PF01496.19 CEP07000.1 - 0 1068.9 11.1 0 1068.5 11.1 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Tmemb_cc2 PF10267.9 CEP07000.1 - 0.048 12.8 5.2 0.11 11.6 5.2 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Receptor_IA-2 PF11548.8 CEP07000.1 - 0.093 12.7 0.1 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 KLRAQ PF10205.9 CEP07000.1 - 0.12 12.6 1.8 0.4 11.0 1.8 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein BBP1_C PF15272.6 CEP07000.1 - 1.5 8.6 5.8 5.7 6.7 0.9 2.4 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal BAR PF03114.18 CEP07001.1 - 1e-33 117.0 10.8 1.5e-33 116.4 10.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CEP07001.1 - 3.2e-14 52.5 0.5 5.8e-14 51.7 0.5 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP07001.1 - 3e-13 49.1 0.1 5.7e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP07001.1 - 1.9e-08 33.9 0.1 4e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain CENP-K PF11802.8 CEP07002.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Pkinase PF00069.25 CEP07003.1 - 1.4e-13 50.8 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07003.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_6 PF12697.7 CEP07004.1 - 4e-09 37.4 0.0 5.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP07004.1 - 8.9e-07 28.4 0.0 6.9e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP07004.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-HIT PF04438.16 CEP07005.1 - 1.5e-10 40.8 11.8 2.3e-10 40.2 11.8 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 CEP07005.1 - 0.039 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain THOC7 PF05615.13 CEP07005.1 - 0.49 10.7 11.4 0.06 13.6 6.6 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Phage_lysozyme2 PF18013.1 CEP07005.1 - 1.8 8.6 4.1 0.76 9.8 1.2 1.8 2 0 0 2 2 2 0 Phage tail lysozyme zf-MYND PF01753.18 CEP07005.1 - 3.2 7.9 11.9 6.4 7.0 11.9 1.5 1 0 0 1 1 1 0 MYND finger PseudoU_synth_1 PF01416.20 CEP07006.1 - 8.2e-13 48.8 0.0 2.3e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase OEP PF02321.18 CEP07006.1 - 0.037 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein adh_short_C2 PF13561.6 CEP07007.1 - 5.9e-54 183.1 5.2 6.9e-54 182.9 5.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP07007.1 - 4.1e-44 150.4 2.8 5.5e-44 150.0 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP07007.1 - 1.8e-07 31.2 1.6 5.3e-07 29.7 1.6 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CEP07007.1 - 0.0019 18.4 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CEP07007.1 - 0.016 14.7 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 CEP07007.1 - 0.032 14.3 0.2 0.064 13.3 0.1 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF676 PF05057.14 CEP07008.1 - 1.4e-42 145.6 0.1 2.3e-42 145.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CEP07008.1 - 2e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CEP07008.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 CEP07008.1 - 0.056 13.1 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CEP07008.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF726 PF05277.12 CEP07008.1 - 0.076 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 CEP07008.1 - 0.1 13.2 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 CEP07008.1 - 0.18 11.3 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family PLDc_N PF13396.6 CEP07008.1 - 0.31 11.0 2.0 0.75 9.8 2.0 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal C2 PF00168.30 CEP07009.1 - 9.1e-22 77.3 0.3 1.1e-21 77.1 0.3 1.1 1 0 0 1 1 1 1 C2 domain Glyco_transf_21 PF13506.6 CEP07010.1 - 1.2e-41 142.1 0.0 1.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CEP07010.1 - 1e-20 74.6 0.0 1.5e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP07010.1 - 5.9e-14 52.4 1.4 1e-13 51.7 1.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP07010.1 - 0.00062 19.6 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 MAM33 PF02330.16 CEP07011.1 - 2.9e-59 200.6 14.9 9.9e-59 198.8 14.9 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein Ribosomal_S13 PF00416.22 CEP07011.1 - 0.041 14.3 1.1 0.095 13.1 1.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Glyco_hydr_116N PF12215.8 CEP07011.1 - 0.095 12.2 0.4 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5051 PF16473.5 CEP07012.1 - 0.013 15.5 0.3 0.051 13.6 0.1 1.9 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like DUF3658 PF12395.8 CEP07012.1 - 0.023 14.6 0.6 0.047 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF4201 PF13870.6 CEP07012.1 - 0.039 13.7 4.0 0.11 12.3 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) RP-C_C PF11800.8 CEP07012.1 - 0.13 12.3 2.5 0.15 12.1 0.0 2.2 2 1 1 3 3 3 0 Replication protein C C-terminal region Tropomyosin_1 PF12718.7 CEP07012.1 - 3 8.0 9.8 0.31 11.2 4.1 2.1 2 0 0 2 2 2 0 Tropomyosin like tRNA-synt_1d PF00750.19 CEP07013.1 - 6.8e-109 364.0 7.7 8.8e-109 363.6 7.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CEP07013.1 - 5.2e-23 81.5 0.0 1.9e-22 79.6 0.0 2.1 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CEP07013.1 - 7.7e-08 32.8 0.0 2.6e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_2 PF13410.6 CEP07013.1 - 0.00022 21.2 0.5 0.00095 19.1 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EMP70 PF02990.16 CEP07014.1 - 4.6e-203 675.6 8.0 6e-203 675.2 8.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SNF2_N PF00176.23 CEP07015.1 - 3e-72 243.2 4.8 1.1e-65 221.6 1.1 3.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP07015.1 - 2.2e-20 73.1 0.2 1.1e-19 70.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP07015.1 - 7.3e-06 25.9 0.3 0.00085 19.1 0.2 3.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP07015.1 - 6.6e-05 23.0 0.1 6.6e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cation_ATPase_C PF00689.21 CEP07016.1 - 1.3e-45 155.3 9.9 1.3e-45 155.3 9.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEP07016.1 - 2.1e-34 118.6 0.3 2.1e-34 118.6 0.3 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEP07016.1 - 1.8e-21 76.0 0.0 3.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP07016.1 - 5.8e-17 62.7 0.0 2.1e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP07016.1 - 4.1e-10 39.2 0.0 1.8e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP07016.1 - 2.9e-05 23.9 0.2 0.0022 17.8 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 CEP07017.1 - 1.3e-13 50.8 3.3 1.7e-13 50.5 2.6 1.6 2 0 0 2 2 2 1 DnaJ domain Gly-zipper_YMGG PF13441.6 CEP07017.1 - 4.7e-05 23.0 3.5 8.4e-05 22.2 3.5 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 CEP07017.1 - 0.0012 18.6 4.2 0.0021 17.8 4.2 1.4 1 0 0 1 1 1 1 Glycine-zipper domain Gly-zipper_Omp PF13488.6 CEP07017.1 - 0.0016 18.4 5.2 0.0029 17.5 5.2 1.4 1 0 0 1 1 1 1 Glycine zipper DUF456 PF04306.13 CEP07017.1 - 0.0044 17.3 0.9 0.0074 16.6 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 CEP07017.1 - 0.041 14.0 5.4 0.089 12.9 5.4 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 CEP07017.1 - 0.078 13.3 1.3 0.14 12.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Rick_17kDa_Anti PF05433.15 CEP07017.1 - 2.6 8.0 9.1 6 6.8 9.1 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain dCMP_cyt_deam_1 PF00383.23 CEP07018.1 - 2.7e-08 33.6 0.1 3.7e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Apolipoprotein PF01442.18 CEP07019.1 - 1.9e-05 24.6 1.2 2.8e-05 24.1 1.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Sec8_exocyst PF04048.14 CEP07019.1 - 0.081 12.8 4.0 0.087 12.7 0.5 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain SF-assemblin PF06705.11 CEP07019.1 - 0.09 12.1 0.8 0.13 11.6 0.8 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_p24 PF05073.12 CEP07019.1 - 0.093 12.5 1.4 0.14 11.9 1.4 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Nup88 PF10168.9 CEP07019.1 - 0.098 10.5 3.0 0.13 10.1 3.0 1.1 1 0 0 1 1 1 0 Nuclear pore component ABC1 PF03109.16 CEP07019.1 - 0.16 12.2 1.1 0.28 11.4 0.6 1.6 2 0 0 2 2 2 0 ABC1 family Fib_alpha PF08702.10 CEP07019.1 - 0.22 11.7 3.4 0.34 11.1 3.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bPH_3 PF14470.6 CEP07020.1 - 0.12 12.8 1.7 0.41 11.0 1.6 2.0 1 1 0 1 1 1 0 Bacterial PH domain DNApol_Exo PF18136.1 CEP07021.1 - 2.8e-104 348.2 0.1 4.6e-104 347.5 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CEP07021.1 - 4.2e-49 167.6 0.0 8.5e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 CEP07021.1 - 0.019 14.7 0.7 0.078 12.7 0.7 1.9 1 1 0 1 1 1 0 3'-5' exonuclease Peroxin-13_N PF04088.13 CEP07022.1 - 2.3e-52 177.2 0.0 3.2e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CEP07022.1 - 4.7e-12 45.4 0.0 9.6e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP07022.1 - 4.2e-11 42.3 0.0 7.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP07022.1 - 1.3e-08 34.5 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HSF_DNA-bind PF00447.17 CEP07023.1 - 1.1e-29 102.9 2.6 1.1e-29 102.9 2.6 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 CEP07023.1 - 2.2e-26 92.2 0.3 4.6e-26 91.2 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain DUF5082 PF16888.5 CEP07023.1 - 0.0027 18.0 3.2 0.0067 16.7 3.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) DivIC PF04977.15 CEP07023.1 - 0.0032 17.2 0.2 0.0069 16.1 0.2 1.6 1 0 0 1 1 1 1 Septum formation initiator TcdA_TcdB PF12919.7 CEP07023.1 - 0.04 13.2 2.7 0.078 12.3 2.7 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain RRM_1 PF00076.22 CEP07024.1 - 5.3e-39 131.9 0.0 4.2e-20 71.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CEP07024.1 - 0.00032 20.3 0.4 0.04 13.6 0.2 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_7 PF16367.5 CEP07024.1 - 0.00047 20.2 0.0 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 CEP07024.1 - 0.00067 19.7 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 CEP07024.1 - 0.017 14.7 0.0 0.39 10.3 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CEP07024.1 - 0.026 14.8 0.0 8.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SMN PF06003.12 CEP07024.1 - 0.41 9.9 3.5 0.58 9.4 3.5 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RCC1 PF00415.18 CEP07025.1 - 1.9e-37 127.6 26.1 1.7e-10 41.3 0.1 9.2 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ApbA PF02558.16 CEP07025.1 - 6.8e-33 113.5 0.0 1.7e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RCC1_2 PF13540.6 CEP07025.1 - 4.2e-30 102.9 35.6 1e-06 28.4 5.3 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ApbA_C PF08546.11 CEP07025.1 - 3.8e-28 98.2 0.1 6.8e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal adh_short PF00106.25 CEP07027.1 - 3.4e-39 134.3 0.2 6.1e-39 133.5 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP07027.1 - 2.8e-27 95.8 0.0 4.1e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP07027.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP07027.1 - 0.00012 21.7 0.1 0.0002 20.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3472 PF11958.8 CEP07028.1 - 1.9e-27 96.8 3.0 2.8e-27 96.3 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 CEP07028.1 - 1.6e-11 44.5 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) BNR PF02012.20 CEP07028.1 - 0.0014 18.3 0.4 0.0058 16.4 0.4 2.1 1 0 0 1 1 1 1 BNR/Asp-box repeat Asp PF00026.23 CEP07029.1 - 8.5e-56 189.7 2.0 1.5e-55 188.8 2.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP07029.1 - 5.7e-13 49.5 5.0 4.2e-11 43.4 5.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Vps51 PF08700.11 CEP07030.1 - 1.9e-25 88.7 1.4 1.9e-25 88.7 1.4 2.6 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 CEP07030.1 - 3.8e-21 75.8 3.7 3.8e-21 75.8 3.7 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 CEP07030.1 - 1.2e-14 53.7 7.4 5.8e-14 51.5 7.4 2.1 1 1 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 CEP07030.1 - 8.2e-09 35.2 4.1 1.5e-08 34.3 4.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CEP07030.1 - 5.5e-06 26.5 0.2 7.6e-05 22.8 0.2 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CEP07030.1 - 1.6e-05 25.1 1.8 1.6e-05 25.1 1.8 2.9 2 1 1 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 CEP07030.1 - 0.00013 22.0 1.3 0.00041 20.4 1.3 1.9 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zw10 PF06248.13 CEP07030.1 - 0.00082 18.1 5.3 0.0014 17.3 5.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 TMF_TATA_bd PF12325.8 CEP07030.1 - 0.00095 19.4 1.0 0.0042 17.3 1.0 2.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Vps53_N PF04100.12 CEP07030.1 - 0.011 14.7 6.2 0.021 13.8 6.2 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal PI3K_P85_iSH2 PF16454.5 CEP07030.1 - 0.068 12.8 3.6 0.071 12.7 0.9 2.4 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Bep_C_terminal PF17841.1 CEP07030.1 - 0.084 13.1 0.2 0.87 9.8 0.1 2.6 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) THOC7 PF05615.13 CEP07030.1 - 0.098 12.9 1.3 0.36 11.1 1.3 2.0 1 0 0 1 1 1 0 Tho complex subunit 7 XhlA PF10779.9 CEP07030.1 - 0.12 12.5 3.0 13 6.1 0.4 3.1 2 0 0 2 2 2 0 Haemolysin XhlA Nsp1_C PF05064.13 CEP07030.1 - 0.19 11.5 4.0 0.14 12.0 1.3 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region ZapB PF06005.12 CEP07030.1 - 0.55 10.7 4.0 0.28 11.6 0.7 2.3 2 0 0 2 2 1 0 Cell division protein ZapB DUF5082 PF16888.5 CEP07030.1 - 0.61 10.4 6.1 12 6.2 2.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Sec8_exocyst PF04048.14 CEP07030.1 - 0.72 9.7 5.2 0.83 9.5 2.8 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BRE1 PF08647.11 CEP07030.1 - 0.74 9.9 5.3 2.6 8.2 2.2 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4795 PF16043.5 CEP07030.1 - 0.92 9.1 6.2 7 6.2 4.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4041 PF13250.6 CEP07030.1 - 1.2 9.0 3.2 20 5.2 0.1 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4041) PhoU PF01895.19 CEP07030.1 - 2.1 8.9 4.7 3.1 8.3 1.0 3.1 3 0 0 3 3 3 0 PhoU domain Seryl_tRNA_N PF02403.22 CEP07030.1 - 2.8 8.2 5.7 8.3 6.7 1.8 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LysM PF01476.20 CEP07032.1 - 3.4e-10 39.8 0.0 2.7e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 LysM domain DUF913 PF06025.12 CEP07032.1 - 0.00064 18.8 1.4 0.00072 18.6 1.4 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF4228 PF14009.6 CEP07032.1 - 0.013 15.9 1.2 0.018 15.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Pex14_N PF04695.13 CEP07032.1 - 0.032 14.9 7.2 0.06 14.0 7.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CNDH2_M PF16869.5 CEP07032.1 - 0.099 13.3 4.3 0.18 12.5 4.3 1.4 1 0 0 1 1 1 0 PF16858 Presenilin PF01080.17 CEP07032.1 - 3.5 6.3 4.3 4.4 6.0 4.3 1.1 1 0 0 1 1 1 0 Presenilin Velvet PF11754.8 CEP07033.1 - 8.2e-45 153.7 2.5 6.9e-33 114.6 0.4 3.0 2 1 1 3 3 3 2 Velvet factor Endonuclease_NS PF01223.23 CEP07034.1 - 2.7e-60 204.0 0.0 3.1e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MobC PF05713.11 CEP07035.1 - 0.0097 16.4 1.5 3 8.4 0.0 2.9 3 0 0 3 3 3 2 Bacterial mobilisation protein (MobC) DUF2408 PF10303.9 CEP07035.1 - 0.015 15.8 2.6 0.045 14.3 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF150 PF02576.17 CEP07035.1 - 0.041 14.3 0.1 4 7.9 0.0 2.3 2 0 0 2 2 2 0 RimP N-terminal domain ABC_tran_CTD PF16326.5 CEP07035.1 - 0.088 13.1 3.0 0.74 10.1 1.4 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain WXG100 PF06013.12 CEP07035.1 - 0.47 10.7 3.5 11 6.3 0.2 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG tRNA-synt_2b PF00587.25 CEP07036.1 - 6e-38 130.6 0.0 1.1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEP07036.1 - 1.3e-19 70.5 11.4 1.3e-19 70.5 11.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA_lig_kinase PF08303.11 CEP07036.1 - 1.1 9.3 5.8 2.2 8.3 5.3 1.8 1 1 1 2 2 2 0 tRNA ligase kinase domain Peptidase_S8 PF00082.22 CEP07037.1 - 4.7e-99 331.4 2.0 3.4e-50 171.0 0.6 2.2 2 0 0 2 2 2 2 Subtilase family PA PF02225.22 CEP07037.1 - 5.1e-22 77.7 0.1 8.1e-11 41.8 0.0 3.2 2 0 0 2 2 2 2 PA domain fn3_5 PF06280.12 CEP07037.1 - 7.6e-19 68.5 3.1 1.6e-08 35.2 1.2 2.5 2 0 0 2 2 2 2 Fn3-like domain DUF4232 PF14016.6 CEP07037.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) Motile_Sperm PF00635.26 CEP07037.1 - 0.29 11.0 1.9 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Plus-3 PF03126.18 CEP07038.1 - 2.4e-35 121.3 0.1 9.1e-35 119.5 0.1 2.1 1 0 0 1 1 1 1 Plus-3 domain YEATS PF03366.16 CEP07038.1 - 7.5e-16 57.9 0.0 1.8e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CEP07038.1 - 0.042 14.0 0.1 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Phage_Coat_A PF05357.13 CEP07038.1 - 1.4 8.8 7.3 3.5 7.5 0.1 3.6 3 0 0 3 3 3 0 Phage Coat Protein A UN_NPL4 PF11543.8 CEP07039.1 - 0.0099 16.3 0.0 0.03 14.8 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 CEP07039.1 - 0.094 12.5 0.1 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family UBX PF00789.20 CEP07039.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 UBX domain Homeodomain PF00046.29 CEP07042.1 - 6.2e-19 67.6 0.9 1.4e-18 66.5 0.9 1.6 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 CEP07042.1 - 0.012 15.5 0.3 0.032 14.1 0.1 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT AAT PF03417.16 CEP07042.1 - 0.032 13.9 0.3 0.032 13.9 0.3 1.6 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Homeobox_KN PF05920.11 CEP07042.1 - 0.04 13.8 0.3 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain HTH_23 PF13384.6 CEP07042.1 - 0.075 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain SUIM_assoc PF16619.5 CEP07042.1 - 2.1 8.5 16.8 1.4 9.0 4.9 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SMC_Nse1 PF07574.13 CEP07043.1 - 1.6e-20 73.8 0.6 4.8e-18 65.7 0.6 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CEP07043.1 - 1.7e-08 34.6 13.2 2.7e-08 34.0 13.2 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 CEP07043.1 - 0.0016 18.7 11.6 0.0026 18.0 11.6 1.4 1 0 0 1 1 1 1 Ring finger domain Acetyltransf_4 PF13420.7 CEP07043.1 - 0.044 13.9 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.6 CEP07043.1 - 1.6 8.3 9.8 1.6 8.4 8.1 1.9 2 0 0 2 2 2 0 PHD-finger DWNN PF08783.11 CEP07044.1 - 1.4e-27 95.8 0.2 2.2e-27 95.1 0.2 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CEP07044.1 - 9.1e-09 35.0 8.1 9.1e-09 35.0 8.1 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 CEP07044.1 - 1.2e-05 25.2 3.0 3.1e-05 23.9 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 CEP07044.1 - 0.00047 20.0 9.1 0.00047 20.0 9.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP07044.1 - 0.0039 17.0 10.6 0.0039 17.0 10.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 CEP07044.1 - 0.0076 16.2 1.3 0.0076 16.2 1.3 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.6 CEP07044.1 - 0.022 15.1 10.8 0.022 15.1 10.8 1.9 2 0 0 2 2 2 0 Ring finger domain zf-CCHC_5 PF14787.6 CEP07044.1 - 0.046 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_6 PF14835.6 CEP07044.1 - 0.14 12.0 4.4 0.28 11.1 4.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 CEP07044.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-RING_UBOX PF13445.6 CEP07044.1 - 0.39 10.8 9.7 1 9.5 9.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP07044.1 - 1.7 8.6 18.2 0.031 14.1 11.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CEP07044.1 - 5.3 6.9 10.9 11 5.9 10.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CEP07044.1 - 8.9 6.4 19.2 1.6 8.8 12.5 2.7 2 1 1 3 3 3 0 zinc-RING finger domain Hydrolase PF00702.26 CEP07045.1 - 2.5e-08 34.5 0.0 3.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP07045.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase V-ATPase_G_2 PF16999.5 CEP07045.1 - 0.15 12.5 1.5 0.25 11.8 1.5 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HSP70 PF00012.20 CEP07046.1 - 5.8e-06 24.8 0.1 2.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Hsp70 protein AF-4 PF05110.13 CEP07046.1 - 0.046 11.8 5.5 0.071 11.2 5.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MreB_Mbl PF06723.13 CEP07046.1 - 0.093 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein DNA_pol_phi PF04931.13 CEP07046.1 - 7.8 4.5 11.5 13 3.7 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cyclin_N PF00134.23 CEP07047.1 - 2.3e-10 40.3 2.0 4.2e-07 29.8 0.1 3.2 2 2 1 3 3 3 2 Cyclin, N-terminal domain TEBP_beta PF07404.11 CEP07047.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) TFIIB PF00382.19 CEP07047.1 - 0.094 12.8 0.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Hist_deacetyl PF00850.19 CEP07048.1 - 3.1e-82 276.5 0.0 4.8e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Ammonium_transp PF00909.21 CEP07049.1 - 1.1e-112 376.7 30.9 1.3e-112 376.5 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CEP07049.1 - 8.8 6.4 11.5 0.082 12.9 1.5 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S BppU_IgG PF18667.1 CEP07050.1 - 0.018 15.2 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 Baseplate upper protein immunoglobulin like domain COX7C PF02935.16 CEP07050.1 - 0.1 12.9 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc PCI PF01399.27 CEP07051.1 - 2.2e-10 41.0 0.3 4.9e-10 39.9 0.3 1.6 1 0 0 1 1 1 1 PCI domain tRNA-synt_His PF13393.6 CEP07052.1 - 2.6e-39 135.3 0.0 2.7e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase Usp PF00582.26 CEP07052.1 - 6.1e-17 62.5 0.0 2.8e-16 60.3 0.0 2.2 1 0 0 1 1 1 1 Universal stress protein family WHEP-TRS PF00458.20 CEP07052.1 - 4.8e-15 55.5 4.5 1.5e-14 53.8 4.5 2.0 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.20 CEP07052.1 - 1.1e-12 47.9 0.5 1e-11 44.8 0.2 2.6 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CEP07052.1 - 0.0029 17.2 0.0 0.0029 17.2 0.0 3.2 3 1 1 4 4 4 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 CEP07052.1 - 0.0096 15.0 1.2 0.064 12.3 1.2 2.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF1820 PF08850.11 CEP07052.1 - 0.055 14.0 0.1 0.21 12.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) ScsC_N PF18312.1 CEP07052.1 - 1.3 8.9 3.6 7 6.6 0.8 3.2 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain RRM_1 PF00076.22 CEP07053.1 - 5.1e-09 35.8 0.1 8.4e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CEP07053.1 - 3.8e-07 30.8 0.1 8.6e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CEP07053.1 - 0.00016 21.6 3.6 0.00016 21.6 3.6 2.2 3 0 0 3 3 3 1 Zinc finger domain RRM_3 PF08777.11 CEP07053.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 CEP07053.1 - 0.003 17.5 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 CEP07053.1 - 0.016 15.5 0.2 0.016 15.5 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH PF00642.24 CEP07053.1 - 0.02 14.8 3.4 0.02 14.8 3.4 2.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.21 CEP07053.1 - 0.029 14.5 0.4 0.029 14.5 0.4 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_4 PF18044.1 CEP07053.1 - 0.029 14.2 3.8 0.074 12.9 3.8 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEP07053.1 - 0.042 14.3 1.9 0.042 14.3 1.9 2.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zinc-ribbons_6 PF07191.12 CEP07053.1 - 4.9 7.2 9.1 16 5.6 9.1 1.9 1 1 0 1 1 1 0 zinc-ribbons Glyco_transf_15 PF01793.16 CEP07054.1 - 1.2e-120 402.7 9.5 1.4e-120 402.4 9.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Choline_transpo PF04515.12 CEP07056.1 - 2.5e-73 247.2 35.7 2.5e-73 247.2 35.7 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Zn_clus PF00172.18 CEP07056.1 - 3.5e-08 33.4 9.8 5.8e-08 32.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRAP PF02586.14 CEP07057.1 - 7.5e-50 169.5 0.1 2.1e-47 161.5 0.1 2.2 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) Beta-TrCP_D PF12125.8 CEP07057.1 - 0.26 11.2 1.3 12 5.8 0.4 2.6 2 0 0 2 2 2 0 D domain of beta-TrCP Nup188 PF10487.9 CEP07058.1 - 2.1e-76 257.6 6.6 6.5e-56 189.8 0.2 2.4 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CEP07058.1 - 0.017 13.9 1.6 0.033 13.0 0.1 2.3 3 0 0 3 3 3 0 Nuclear pore protein NUP188 C-terminal domain UQ_con PF00179.26 CEP07062.1 - 2.7e-32 111.3 0.3 5.5e-32 110.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 120_Rick_ant PF12574.8 CEP07062.1 - 0.02 14.1 0.2 0.05 12.8 0.2 1.6 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Abhydrolase_8 PF06259.12 CEP07062.1 - 0.064 12.9 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase Myb_DNA-binding PF00249.31 CEP07063.1 - 5.5e-07 29.7 0.1 0.032 14.4 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP07063.1 - 8.4e-05 22.7 4.7 0.02 15.1 0.1 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DNA_primase_S PF01896.19 CEP07063.1 - 0.026 14.6 0.2 0.1 12.7 0.0 2.2 2 1 0 2 2 2 0 DNA primase small subunit Bromodomain PF00439.25 CEP07064.1 - 3.9e-18 65.3 0.5 9e-18 64.1 0.5 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CEP07064.1 - 4.3e-08 33.4 0.0 4.3e-08 33.4 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP07064.1 - 7.5e-05 22.7 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP07064.1 - 0.00033 21.0 0.1 0.00073 19.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCAF_N PF06466.11 CEP07064.1 - 0.0025 17.4 0.1 0.0055 16.3 0.1 1.5 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain DNA_pack_N PF02500.15 CEP07064.1 - 0.031 14.1 0.2 0.069 13.0 0.2 1.5 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus FadA PF09403.10 CEP07065.1 - 4.1 7.9 12.0 0.88 10.1 6.0 2.8 3 1 1 4 4 4 0 Adhesion protein FadA Peptidase_M19 PF01244.21 CEP07066.1 - 1.8e-112 375.6 0.0 2.2e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RRM_1 PF00076.22 CEP07067.1 - 3.8e-35 119.5 0.2 1.4e-16 60.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP07067.1 - 1.4e-10 41.1 6.5 4.3e-05 23.6 0.0 3.6 3 2 0 3 3 2 2 RNA recognition motif TFIIA PF03153.13 CEP07067.1 - 1.2e-05 25.6 37.1 1.2e-05 25.6 37.1 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 CEP07067.1 - 0.013 15.5 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Exonuc_VII_L PF02601.15 CEP07067.1 - 0.35 10.4 15.5 0.69 9.4 15.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit NEMP PF10225.9 CEP07067.1 - 0.73 9.5 5.9 1.2 8.7 5.9 1.3 1 0 0 1 1 1 0 NEMP family RRM_3 PF08777.11 CEP07067.1 - 1.1 9.3 7.6 7.1 6.7 0.0 3.5 3 0 0 3 3 2 0 RNA binding motif GEMIN8 PF15348.6 CEP07067.1 - 1.8 8.8 39.3 0.12 12.7 29.2 3.1 3 1 1 4 4 4 0 Gemini of Cajal bodies-associated protein 8 RskA PF10099.9 CEP07067.1 - 3.1 8.1 0.0 3.1 8.1 0.0 2.9 2 1 0 2 2 1 0 Anti-sigma-K factor rskA ERO1 PF04137.15 CEP07067.1 - 3.9 6.6 15.5 10 5.2 15.5 1.6 1 1 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Ndc1_Nup PF09531.10 CEP07067.1 - 5.9 5.4 14.3 8.6 4.9 14.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tubulin PF00091.25 CEP07068.1 - 2.4e-61 207.4 0.0 4.2e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP07068.1 - 2.1e-40 137.8 0.0 3.2e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CEP07068.1 - 0.062 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 CEP07068.1 - 0.084 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain CGGC PF08821.11 CEP07070.1 - 0.011 16.0 3.8 0.024 14.8 3.3 1.9 1 1 0 1 1 1 0 CGGC domain HMG_box PF00505.19 CEP07073.1 - 4.8e-37 126.2 3.2 4.7e-18 65.4 0.2 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP07073.1 - 3.4e-29 101.2 1.7 2.2e-13 50.6 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 CEP07073.1 - 0.0017 18.3 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain CCD PF07860.11 CEP07073.1 - 0.077 13.0 0.0 0.077 13.0 0.0 2.8 4 0 0 4 4 4 0 WisP family C-Terminal Region HMG_box_5 PF14887.6 CEP07073.1 - 0.93 9.5 5.1 0.23 11.4 1.1 2.2 2 1 0 2 2 2 0 HMG (high mobility group) box 5 Pkinase PF00069.25 CEP07074.1 - 6.3e-24 84.8 0.0 9.2e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Metallophos PF00149.28 CEP07074.1 - 9.5e-13 49.1 0.2 2.1e-12 48.0 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_fungal PF17667.1 CEP07074.1 - 7.1e-11 41.5 0.6 1.7e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEP07074.1 - 2.1e-10 40.3 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Spt20 PF12090.8 CEP07074.1 - 0.049 13.3 3.9 0.093 12.3 3.9 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_M20 PF01546.28 CEP07075.1 - 1.2e-33 116.6 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEP07075.1 - 9.4e-12 44.8 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CEP07075.1 - 0.0011 18.7 0.0 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 WG_beta_rep PF14903.6 CEP07075.1 - 0.041 14.2 1.2 0.079 13.3 0.1 2.1 2 0 0 2 2 2 0 WG containing repeat Bromodomain PF00439.25 CEP07076.1 - 1.4e-16 60.3 0.0 3.6e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 CEP07076.1 - 7.4e-12 45.2 2.1 1.8e-06 27.5 0.3 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07076.1 - 1.1e-07 31.4 1.0 0.007 15.7 0.6 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CEP07076.1 - 0.051 12.9 0.2 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP07076.1 - 0.45 9.2 4.8 0.17 10.6 0.1 2.1 2 0 0 2 2 2 0 Fungal protein kinase RVT_1 PF00078.27 CEP07078.1 - 3.8e-18 65.8 0.0 4.7e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sec7 PF01369.20 CEP07079.1 - 1.4e-30 106.3 0.3 3e-30 105.2 0.3 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CEP07079.1 - 1.6e-23 83.3 0.1 4.6e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP07079.1 - 3.1e-05 24.4 0.0 0.00053 20.5 0.0 2.8 1 1 0 1 1 1 1 PH domain PIF1 PF05970.14 CEP07080.1 - 8.4e-14 51.5 0.0 9.5e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase HTH_Tnp_1 PF01527.20 CEP07081.1 - 1.9e-06 28.0 0.1 6.4e-06 26.4 0.0 1.8 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.15 CEP07081.1 - 7.9e-05 22.6 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP07081.1 - 0.00012 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP07081.1 - 0.00072 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 CEP07081.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF1836 PF08876.11 CEP07081.1 - 0.018 15.1 0.2 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) TrmB PF01978.19 CEP07081.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 CEP07081.1 - 0.053 13.6 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_37 PF13744.6 CEP07081.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CEP07081.1 - 0.081 12.6 0.0 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_32 PF13565.6 CEP07081.1 - 0.089 13.4 0.4 0.31 11.7 0.3 1.9 1 1 1 2 2 2 0 Homeodomain-like domain Chromo PF00385.24 CEP07084.1 - 4.9e-09 36.0 0.4 7.6e-09 35.3 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEP07084.1 - 0.017 15.3 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 GCR1_C PF12550.8 CEP07085.1 - 7.2e-20 71.1 3.4 1.3e-19 70.3 3.4 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.11 CEP07085.1 - 0.0012 19.1 0.8 0.0012 19.1 0.8 1.5 2 0 0 2 2 2 1 QacR-like protein, C-terminal region rve PF00665.26 CEP07086.1 - 2.5e-16 59.9 0.0 4.3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP07086.1 - 3.5e-08 33.4 0.1 6.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP07086.1 - 8.3e-07 29.1 0.2 1.6e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger zf-UBR PF02207.20 CEP07087.1 - 1.8e-20 72.9 10.9 4.8e-20 71.5 10.9 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CEP07087.1 - 3.6e-08 33.1 0.0 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS F-box-like PF12937.7 CEP07088.1 - 8.9e-09 35.1 0.3 2.6e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07088.1 - 5.1e-07 29.4 0.4 1.2e-06 28.2 0.4 1.6 1 0 0 1 1 1 1 F-box domain DUF3760 PF12586.8 CEP07088.1 - 0.084 13.1 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) LRR_4 PF12799.7 CEP07088.1 - 4.5 7.8 11.0 25 5.5 3.2 4.4 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Med29 PF11568.8 CEP07089.1 - 0.48 10.6 5.4 0.13 12.5 1.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 29 Integrase_H2C2 PF17921.1 CEP07090.1 - 2.5e-17 62.7 0.1 6.5e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP07090.1 - 2.5e-12 47.0 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP07090.1 - 3.4e-07 30.3 0.0 8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Glyco_transf_90 PF05686.12 CEP07090.1 - 0.0059 15.6 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 90 rve_3 PF13683.6 CEP07090.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RecG_N PF17190.4 CEP07090.1 - 0.089 13.5 4.6 0.8 10.5 0.1 2.9 2 1 1 3 3 3 0 RecG N-terminal helical domain DUF2284 PF10050.9 CEP07090.1 - 0.13 12.0 0.4 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) RT_RNaseH_2 PF17919.1 CEP07091.1 - 6.7e-31 106.3 0.0 1.4e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP07091.1 - 3.2e-27 94.9 0.1 7.5e-27 93.7 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP07091.1 - 2e-14 53.6 0.1 2.4e-13 50.1 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP07091.1 - 0.003 18.2 0.0 0.0093 16.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP07091.1 - 0.0076 16.8 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease VPR PF00522.18 CEP07092.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 VPR/VPX protein RVT_1 PF00078.27 CEP07094.1 - 2.1e-26 92.9 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HDC PF02329.16 CEP07094.1 - 0.044 12.8 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Histidine carboxylase PI chain Helitron_like_N PF14214.6 CEP07095.1 - 8.6e-31 107.6 0.2 1.5e-30 106.9 0.2 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 CEP07095.1 - 0.0086 15.2 4.2 0.12 11.4 4.2 2.2 1 1 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) InvH PF04741.12 CEP07097.1 - 0.067 13.1 0.6 0.11 12.4 0.4 1.4 1 1 0 1 1 1 0 InvH outer membrane lipoprotein Helo_like_N PF17111.5 CEP07098.1 - 0.028 13.8 0.3 0.042 13.2 0.3 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF3895 PF13034.6 CEP07098.1 - 0.14 12.2 0.0 0.67 10.0 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3895) 5_3_exonuc PF01367.20 CEP07099.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold dCMP_cyt_deam_1 PF00383.23 CEP07100.1 - 2.9e-10 39.9 0.0 4.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP07100.1 - 4.7e-08 32.9 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CEP07100.1 - 0.011 15.7 0.3 0.1 12.7 0.3 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase DUF573 PF04504.14 CEP07100.1 - 0.018 15.7 0.2 0.041 14.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 zf-met PF12874.7 CEP07101.1 - 1.3e-24 85.8 86.9 0.001 19.4 1.8 15.3 15 0 0 15 15 15 9 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP07101.1 - 9.5e-22 76.8 98.1 0.0014 18.8 1.6 15.3 16 0 0 16 16 16 11 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEP07101.1 - 2.5e-19 69.5 58.2 0.0023 18.2 0.1 11.8 3 3 9 13 13 13 12 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEP07101.1 - 2e-12 46.8 150.9 0.023 15.5 1.8 16.3 16 0 0 16 16 16 10 C2H2-type zinc finger DUF629 PF04780.12 CEP07101.1 - 1.1e-09 37.4 64.4 0.056 12.0 1.0 14.6 15 1 1 16 16 16 7 Protein of unknown function (DUF629) ASFV_p27 PF06556.11 CEP07101.1 - 3.7e-05 23.8 18.2 0.31 11.2 0.0 8.4 5 4 4 9 9 9 1 IAP-like protein p27 C-terminus zf-Dof PF02701.15 CEP07101.1 - 6.3e-05 23.1 50.1 0.14 12.3 0.0 11.9 13 0 0 13 13 13 3 Dof domain, zinc finger zf-AD PF07776.15 CEP07101.1 - 0.0079 16.4 33.7 0.91 9.8 0.2 9.1 7 2 3 10 10 9 3 Zinc-finger associated domain (zf-AD) zf_C2H2_ZHX PF18387.1 CEP07101.1 - 0.04 13.5 56.2 1.5 8.5 0.1 13.3 14 0 0 14 14 14 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 CEP07101.1 - 0.07 13.9 39.0 2.8 8.8 0.6 9.0 1 1 10 13 13 13 0 zinc-ribbon family Trm112p PF03966.16 CEP07101.1 - 0.34 11.5 22.1 2.9 8.5 0.0 7.8 9 2 0 9 9 9 0 Trm112p-like protein FOXP-CC PF16159.5 CEP07101.1 - 0.41 11.3 35.0 34 5.2 0.1 10.8 12 0 0 12 12 11 0 FOXP coiled-coil domain Peptidase_M16_C PF05193.21 CEP07102.1 - 6e-27 94.8 0.0 1.4e-18 67.5 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEP07102.1 - 3e-09 37.0 1.2 1.1e-05 25.5 0.0 3.5 3 1 0 3 3 3 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 CEP07102.1 - 1.3 8.1 6.8 11 5.1 3.8 2.6 2 1 0 2 2 2 0 Peptidase M16C associated Tctex-1 PF03645.13 CEP07103.1 - 5.4e-27 94.0 1.8 7.7e-27 93.5 1.7 1.3 1 1 0 1 1 1 1 Tctex-1 family DUF2961 PF11175.8 CEP07103.1 - 0.044 13.4 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) CENP-T_C PF15511.6 CEP07104.1 - 2.8e-10 40.3 0.1 3.7e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold zf-RVT PF13966.6 CEP07107.1 - 9.8e-06 26.2 0.1 1.8e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase UCR_6-4kD PF08997.10 CEP07107.1 - 0.0013 18.6 0.2 0.0031 17.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Exc PF07825.11 CEP07107.1 - 0.041 13.9 0.6 0.07 13.1 0.6 1.4 1 0 0 1 1 1 0 Excisionase-like protein DDE_3 PF13358.6 CEP07108.1 - 3.9e-18 65.6 0.1 4.4e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4007 PF13182.6 CEP07109.1 - 0.03 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) SLAM PF06214.11 CEP07109.1 - 0.072 13.1 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein DUF1729 PF08354.10 CEP07111.1 - 8.8e-151 501.8 0.0 1.5e-150 501.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CEP07111.1 - 7.8e-73 245.7 0.2 3e-72 243.8 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain FAS_I_H PF18314.1 CEP07111.1 - 2.6e-69 232.9 0.0 4.9e-69 232.0 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 CEP07111.1 - 1.3e-67 227.2 0.0 3.2e-67 225.9 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 CEP07111.1 - 8.2e-47 158.7 0.0 2.1e-46 157.4 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 CEP07111.1 - 7.6e-30 103.0 0.1 1.9e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 CEP07111.1 - 1.8e-29 103.2 0.0 4.6e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 CEP07111.1 - 1.1e-27 96.6 0.2 2.6e-27 95.4 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 CEP07111.1 - 2.5e-21 76.4 0.5 5.8e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.6 CEP07111.1 - 2e-17 63.6 0.0 6.9e-17 61.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ACPS PF01648.20 CEP07111.1 - 7.1e-16 58.4 0.0 1.9e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CEP07111.1 - 5e-11 42.7 0.0 1.6e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CEP07111.1 - 0.014 14.7 0.3 0.031 13.6 0.3 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain KR PF08659.10 CEP07111.1 - 0.1 12.5 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 KR domain Pkinase PF00069.25 CEP07112.1 - 3.6e-39 134.7 0.2 1.2e-38 133.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07112.1 - 3.9e-21 75.5 0.9 1.1e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP07112.1 - 4.1e-06 26.3 0.0 4.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CRT10 PF08728.10 CEP07112.1 - 0.059 11.5 13.3 0.098 10.8 13.3 1.3 1 0 0 1 1 1 0 CRT10 DDE_3 PF13358.6 CEP07115.1 - 9.9e-20 70.8 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease NB-ARC PF00931.22 CEP07115.1 - 0.096 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RT_RNaseH PF17917.1 CEP07116.1 - 1.5e-35 121.7 0.0 4.7e-35 120.0 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP07116.1 - 4.2e-35 119.8 0.0 1.1e-34 118.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP07116.1 - 1.4e-19 69.9 0.0 1e-18 67.1 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CEP07116.1 - 6.9e-19 68.2 0.0 1.7e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CEP07116.1 - 4.3e-10 40.0 0.1 1.6e-09 38.2 0.1 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP07116.1 - 7.4e-08 32.2 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP07116.1 - 1e-07 32.5 0.1 8.4e-07 29.5 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease RVT_1 PF00078.27 CEP07116.1 - 1.7e-07 31.0 0.1 5.6e-05 22.8 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP07116.1 - 0.00033 20.6 5.2 0.00068 19.6 5.2 1.5 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.6 CEP07116.1 - 0.0011 18.7 0.1 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DNA_pol_viral_C PF00336.18 CEP07116.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVP PF00077.20 CEP07116.1 - 0.14 12.5 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.26 CEP07117.1 - 1.2e-19 70.7 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP07117.1 - 0.00082 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.15 CEP07117.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase RasGEF PF00617.19 CEP07119.1 - 3.6e-59 199.9 2.7 3.9e-59 199.8 0.8 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEP07119.1 - 2.5e-25 88.7 1.0 1.1e-24 86.7 1.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 CEP07119.1 - 1.6e-09 37.6 3.6 3.8e-09 36.5 3.6 1.6 1 0 0 1 1 1 1 WW domain CAS_C PF12026.8 CEP07119.1 - 0.00069 19.8 0.4 0.00069 19.8 0.4 2.7 3 1 0 3 3 3 1 Crk-Associated Substrate C-terminal domain PepX_N PF09168.10 CEP07119.1 - 0.064 13.7 1.4 0.19 12.1 1.4 1.8 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DUF5398 PF17376.2 CEP07119.1 - 0.11 13.2 0.0 0.48 11.1 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5398) NDK PF00334.19 CEP07119.1 - 0.12 12.4 0.2 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Nucleoside diphosphate kinase Exo_endo_phos_2 PF14529.6 CEP07120.1 - 3.5e-13 49.4 1.6 3.9e-13 49.3 0.3 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP07120.1 - 0.0041 16.7 1.5 0.0052 16.3 0.2 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Mononeg_mRNAcap PF14318.6 CEP07121.1 - 6.5e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Mononegavirales mRNA-capping region V RVT_1 PF00078.27 CEP07122.1 - 1.6e-27 96.5 0.4 3.4e-27 95.4 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP07122.1 - 6.3e-10 39.5 0.0 1.5e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CEP07122.1 - 4.5e-09 36.2 0.1 9.3e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP07122.1 - 3.9e-08 33.1 0.1 7.4e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP07122.1 - 3.4e-07 30.8 0.0 7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 CEP07122.1 - 6.5e-05 22.5 0.4 6.5e-05 22.5 0.4 1.7 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) RVP PF00077.20 CEP07122.1 - 0.014 15.7 0.1 0.074 13.4 0.1 2.3 1 1 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2B PF12384.8 CEP07122.1 - 0.062 12.8 1.0 0.13 11.8 0.2 1.9 2 0 0 2 2 2 0 Ty3 transposon peptidase DUF4381 PF14316.6 CEP07123.1 - 0.088 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-MIZ PF02891.20 CEP07124.1 - 1.5e-18 66.2 2.5 3.1e-18 65.2 2.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Zmiz1_N PF18028.1 CEP07124.1 - 2.2e-10 40.7 0.1 5.5e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain zf-Nse PF11789.8 CEP07124.1 - 1.2e-05 25.0 1.1 3e-05 23.7 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_S8 PF00410.19 CEP07124.1 - 0.6 10.1 2.2 1.8 8.6 2.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S8 Phosphodiest PF01663.22 CEP07126.1 - 8.8e-75 252.5 2.6 2e-72 244.8 2.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HNOB PF07700.15 CEP07126.1 - 0.092 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Haem-NO-binding Methyltransf_25 PF13649.6 CEP07129.1 - 3.9e-15 56.3 0.0 9.2e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP07129.1 - 6.6e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP07129.1 - 2.2e-11 44.3 0.0 8e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP07129.1 - 1.4e-10 41.1 0.0 9.7e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP07129.1 - 8.5e-09 35.1 0.0 4.3e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 CEP07129.1 - 2e-07 31.7 0.0 4.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP07129.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CEP07129.1 - 0.0026 17.7 0.0 0.0085 16.0 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 CEP07129.1 - 0.0061 16.1 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain CheR PF01739.18 CEP07129.1 - 0.019 14.5 0.0 6.2 6.3 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 CEP07129.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 CEP07129.1 - 0.027 14.6 0.0 0.077 13.1 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 CEP07129.1 - 0.041 12.8 0.1 0.09 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PCMT PF01135.19 CEP07129.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.22 CEP07130.1 - 1.9e-14 53.2 0.0 2.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CEP07130.1 - 1.8e-08 34.1 4.8 2.8e-08 33.5 4.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEP07130.1 - 0.16 11.9 1.4 0.34 10.8 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP07130.1 - 0.29 11.1 2.3 0.57 10.2 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RPA PF10134.9 CEP07131.1 - 0.036 13.5 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Replication initiator protein A HATPase_c PF02518.26 CEP07131.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HGTP_anticodon PF03129.20 CEP07132.1 - 5.2e-21 74.6 0.0 1.9e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CEP07132.1 - 6.1e-09 36.1 0.0 2.9e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2849 PF11011.8 CEP07132.1 - 1.2 9.9 8.4 1.7 9.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) zf-C2HC5 PF06221.13 CEP07133.1 - 4.1e-22 77.9 7.3 7.1e-22 77.2 7.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type HisK_sensor PF18698.1 CEP07134.1 - 5.2 7.5 8.0 1.3 9.4 4.3 1.9 2 0 0 2 2 2 0 Histidine kinase sensor domain Ribosomal_L22 PF00237.19 CEP07135.1 - 5.8e-40 135.7 0.1 7.8e-40 135.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4570 PF15134.6 CEP07137.1 - 0.7 9.9 6.3 0.21 11.6 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DUF745 PF05335.13 CEP07137.1 - 0.8 9.4 13.1 0.13 12.0 9.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.13 CEP07137.1 - 6.3 7.6 9.5 1.5 9.6 0.1 3.2 3 0 0 3 3 3 0 Occludin homology domain DUF4611 PF15387.6 CEP07137.1 - 6.4 7.1 11.0 0.19 12.0 3.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) GATA PF00320.27 CEP07140.1 - 6.4e-17 60.9 4.6 1.2e-16 60.0 4.6 1.5 1 0 0 1 1 1 1 GATA zinc finger CDC45 PF02724.14 CEP07140.1 - 0.00062 18.2 5.9 0.00068 18.1 5.9 1.2 1 0 0 1 1 1 1 CDC45-like protein Zn-ribbon_8 PF09723.10 CEP07140.1 - 0.026 14.6 0.3 0.06 13.5 0.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 CEP07140.1 - 0.88 9.5 3.3 1.7 8.7 3.3 1.4 1 0 0 1 1 1 0 Nudix N-terminal zf-3CxxC PF13695.6 CEP07140.1 - 0.97 9.9 5.5 0.39 11.2 1.3 2.5 2 1 0 3 3 3 0 Zinc-binding domain FAM163 PF15069.6 CEP07140.1 - 2.7 8.4 6.4 1.4 9.4 3.4 2.3 1 1 1 2 2 2 0 FAM163 family NOA36 PF06524.12 CEP07140.1 - 5.6 6.2 13.6 9.4 5.5 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein Peptidase_M41 PF01434.18 CEP07141.1 - 3.2e-66 222.8 1.3 6.8e-66 221.8 1.3 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CEP07141.1 - 3.5e-43 147.2 0.0 1.5e-42 145.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP07141.1 - 2.1e-11 43.4 0.0 4.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEP07141.1 - 1.7e-06 28.1 0.0 5.1e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP07141.1 - 4e-06 27.3 0.1 0.00019 21.9 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEP07141.1 - 7.9e-06 26.2 0.1 0.013 15.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CEP07141.1 - 1.9e-05 24.1 0.1 5.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 CEP07141.1 - 8.3e-05 22.4 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEP07141.1 - 0.00015 22.0 0.0 0.00078 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEP07141.1 - 0.00088 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEP07141.1 - 0.0048 17.4 0.0 0.019 15.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CEP07141.1 - 0.0052 16.2 0.5 0.014 14.8 0.5 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEP07141.1 - 0.0084 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CEP07141.1 - 0.013 15.5 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEP07141.1 - 0.014 14.9 0.7 0.37 10.3 0.3 2.5 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEP07141.1 - 0.015 15.6 0.0 0.071 13.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 CEP07141.1 - 0.02 15.1 0.2 0.094 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CEP07141.1 - 0.023 14.4 0.1 0.34 10.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 CEP07141.1 - 0.032 14.2 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CEP07141.1 - 0.049 13.6 0.2 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEP07141.1 - 0.05 13.1 0.0 0.34 10.4 0.1 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CEP07141.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEP07141.1 - 0.19 11.5 2.8 1.4 8.6 0.1 3.0 2 2 1 3 3 3 0 AAA domain ATPase PF06745.13 CEP07141.1 - 0.21 10.9 6.2 0.91 8.8 0.2 3.9 4 1 0 4 4 4 0 KaiC AAA_19 PF13245.6 CEP07141.1 - 0.65 10.3 3.1 1.8 8.9 0.3 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CEP07141.1 - 0.85 8.9 4.9 0.66 9.2 0.4 2.5 2 1 1 3 3 3 0 Zeta toxin Apolipoprotein PF01442.18 CEP07142.1 - 2.3e-05 24.4 15.2 0.0054 16.6 5.8 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain RCDG1 PF15725.5 CEP07142.1 - 0.0023 18.3 0.0 0.0042 17.5 0.0 1.4 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein UPF0242 PF06785.11 CEP07142.1 - 0.11 12.6 2.8 0.17 12.0 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ApoO PF09769.9 CEP07142.1 - 0.67 9.9 5.7 0.64 10.0 1.4 2.4 1 1 1 2 2 2 0 Apolipoprotein O Atg14 PF10186.9 CEP07142.1 - 0.73 8.9 5.8 1.1 8.3 5.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HisKA_3 PF07730.13 CEP07142.1 - 0.87 10.1 2.9 2.3 8.8 0.2 2.4 1 1 0 2 2 2 0 Histidine kinase DUF948 PF06103.11 CEP07142.1 - 1.8 8.9 7.6 12 6.3 2.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP-synt_B PF00430.18 CEP07142.1 - 1.8 8.6 25.0 0.58 10.2 10.3 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) BssC_TutF PF08201.11 CEP07142.1 - 3.2 7.8 8.4 12 6.0 0.5 2.9 1 1 2 3 3 3 0 BssC/TutF protein DUF1664 PF07889.12 CEP07142.1 - 3.8 7.6 9.5 1.5 8.9 2.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 CEP07142.1 - 4.2 8.0 21.9 4.9 7.8 2.5 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1451 PF07295.11 CEP07142.1 - 8.6 6.4 11.0 6.6 6.8 2.2 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Spc7 PF08317.11 CEP07142.1 - 8.9 5.1 13.4 13 4.6 13.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MFS_1 PF07690.16 CEP07143.1 - 6.8e-16 58.1 32.9 6.8e-16 58.1 32.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 CEP07143.1 - 0.029 14.8 0.2 0.029 14.8 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF983) CPP1-like PF11833.8 CEP07143.1 - 0.71 9.5 14.9 4.2 7.0 0.1 3.5 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like UPF1_Zn_bind PF09416.10 CEP07144.1 - 3.2e-75 251.2 5.6 6.9e-75 250.1 4.9 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CEP07144.1 - 1.1e-57 194.9 0.0 2.1e-57 194.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP07144.1 - 2.1e-50 171.9 3.2 1.7e-27 96.8 0.3 2.5 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CEP07144.1 - 8.7e-33 112.4 0.0 2.2e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CEP07144.1 - 2.8e-14 53.3 0.0 9.9e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP07144.1 - 1.3e-11 45.0 0.1 5.5e-11 43.0 0.1 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 CEP07144.1 - 9.4e-06 25.7 0.6 1.7e-05 24.9 0.0 1.7 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CEP07144.1 - 1.6e-05 24.8 0.0 0.31 10.7 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CEP07144.1 - 0.00022 20.6 1.5 0.0038 16.5 0.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CEP07144.1 - 0.00044 20.2 0.0 0.00096 19.1 0.0 1.6 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 CEP07144.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_10 PF12846.7 CEP07144.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 CEP07144.1 - 0.014 15.2 0.1 0.041 13.7 0.1 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP07144.1 - 0.016 15.5 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEP07144.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CEP07144.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13_N PF08069.12 CEP07144.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain NACHT PF05729.12 CEP07144.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 CEP07144.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 CEP07144.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC ANAPC4 PF12896.7 CEP07146.1 - 9.7e-27 93.8 3.2 1.7e-26 93.0 3.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Kinesin PF00225.23 CEP07147.1 - 3e-77 259.8 0.1 3e-77 259.8 0.1 3.0 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CEP07147.1 - 0.0011 19.0 0.3 0.0066 16.4 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding PilN_bio_d PF18222.1 CEP07147.1 - 0.038 14.4 0.5 0.22 12.0 0.3 2.4 2 0 0 2 2 2 0 PilN biogenesis protein dimerization domain FlxA PF14282.6 CEP07147.1 - 0.48 10.4 0.0 0.48 10.4 0.0 8.6 10 1 0 10 10 10 0 FlxA-like protein DUF1192 PF06698.11 CEP07147.1 - 2.6 8.1 22.1 0.24 11.5 1.6 6.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1192) Phage_int_SAM_1 PF02899.17 CEP07148.1 - 0.00051 20.3 1.0 0.0012 19.1 0.7 1.7 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP07148.1 - 0.0069 16.8 0.3 0.013 15.9 0.3 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Cas_GSU0054 PF09609.10 CEP07148.1 - 0.091 11.5 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) Cut8 PF08559.10 CEP07149.1 - 3.8e-51 174.0 0.6 4.7e-51 173.7 0.6 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Aminotran_4 PF01063.19 CEP07150.1 - 5e-32 111.6 0.0 6.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MRP_L53 PF10780.9 CEP07151.1 - 2.3e-12 46.9 0.1 3.6e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Met_synt_B12 PF02965.17 CEP07152.1 - 4.5e-121 403.5 0.0 7e-121 402.9 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 CEP07152.1 - 4.4e-77 259.5 0.0 1e-76 258.3 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 CEP07152.1 - 2.4e-57 194.4 0.3 8.7e-57 192.6 0.3 2.0 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 CEP07152.1 - 9.5e-23 80.4 0.3 6.6e-22 77.7 0.1 2.6 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 CEP07152.1 - 3.2e-18 65.9 0.7 4.6e-17 62.2 0.4 2.7 2 0 0 2 2 2 1 B12 binding domain Nop14 PF04147.12 CEP07153.1 - 0.02 13.2 28.4 0.02 13.1 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 CEP07153.1 - 0.044 13.2 24.9 0.046 13.1 24.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 CEP07153.1 - 0.052 12.5 21.2 0.058 12.4 21.2 1.1 1 0 0 1 1 1 0 Paf1 DUF5523 PF17661.1 CEP07153.1 - 0.064 12.9 19.3 0.073 12.8 19.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Mpp10 PF04006.12 CEP07153.1 - 0.08 11.4 27.2 0.1 11.0 27.2 1.1 1 0 0 1 1 1 0 Mpp10 protein POX PF07526.11 CEP07153.1 - 0.099 13.2 3.2 0.16 12.6 3.2 1.3 1 0 0 1 1 1 0 Associated with HOX CDC45 PF02724.14 CEP07153.1 - 0.26 9.5 23.0 0.27 9.5 23.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CEP07153.1 - 0.26 11.4 4.6 0.31 11.1 4.6 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 CEP07153.1 - 0.39 8.6 8.5 0.38 8.6 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SDA1 PF05285.12 CEP07153.1 - 0.4 10.0 34.8 0.48 9.8 34.8 1.1 1 0 0 1 1 1 0 SDA1 Pannexin_like PF12534.8 CEP07153.1 - 1.1 8.3 4.6 1.3 8.0 4.6 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 RR_TM4-6 PF06459.12 CEP07153.1 - 1.1 9.0 16.7 1.4 8.7 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CEP07153.1 - 1.3 7.9 9.8 1.5 7.7 9.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PTPRCAP PF15713.5 CEP07153.1 - 1.3 9.3 26.8 2.4 8.4 26.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4820 PF16091.5 CEP07153.1 - 1.5 8.1 12.6 2.2 7.6 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RRN3 PF05327.11 CEP07153.1 - 2 6.9 20.9 2 6.9 20.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tub_N PF16322.5 CEP07153.1 - 2.3 8.6 19.9 2.9 8.2 19.9 1.2 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 CEP07153.1 - 2.4 7.4 27.5 2.9 7.1 27.5 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 CEP07153.1 - 2.6 6.5 27.9 2.7 6.5 27.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ALMT PF11744.8 CEP07153.1 - 4.3 6.1 5.3 5.1 5.8 5.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 CEP07153.1 - 4.7 5.9 10.7 5.2 5.7 10.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CEP07153.1 - 7.8 5.6 9.1 8.1 5.6 9.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.8 CEP07153.1 - 8.5 5.2 13.6 8.4 5.2 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Phage_integrase PF00589.22 CEP07154.1 - 0.00067 19.5 0.1 0.002 17.9 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family TAXi_N PF14543.6 CEP07154.1 - 0.015 15.5 1.8 0.024 14.9 1.8 1.2 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Mg_chelatase PF01078.21 CEP07154.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5003 PF16394.5 CEP07155.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) PIF1 PF05970.14 CEP07156.1 - 6.8e-11 41.9 0.0 7.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Integrase_H2C2 PF17921.1 CEP07157.1 - 5.9e-18 64.7 0.1 1.4e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP07157.1 - 1.8e-16 59.8 2.1 6.8e-16 57.9 2.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP07157.1 - 1.4e-15 57.5 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CEP07157.1 - 3.1e-14 53.1 0.8 8.6e-14 51.7 0.8 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEP07157.1 - 2.7e-05 24.3 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 CEP07159.1 - 7.4e-08 32.6 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP07159.1 - 2.3e-05 24.1 0.0 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BTG PF07742.12 CEP07159.1 - 0.057 13.3 0.2 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 BTG family XRN1_D2_D3 PF18334.1 CEP07159.1 - 0.072 13.3 0.6 4.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain T7SS_ESX1_EccB PF05108.13 CEP07159.1 - 0.2 10.3 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B SopA PF13981.6 CEP07160.1 - 0.024 15.1 0.4 0.2 12.1 0.0 2.2 2 1 0 2 2 2 0 SopA-like central domain YrzK PF17449.2 CEP07160.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized YrzK-like APG6_N PF17675.1 CEP07161.1 - 0.012 16.1 0.6 0.018 15.6 0.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Fzo_mitofusin PF04799.13 CEP07161.1 - 0.041 13.4 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region CdvA PF18822.1 CEP07161.1 - 0.43 10.4 3.0 2.3 8.1 1.1 2.5 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Ketoacyl-synt_C PF02801.22 CEP07162.1 - 2.2e-33 114.8 0.4 3.5e-33 114.1 0.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CEP07162.1 - 1.8e-28 99.8 1.2 4.7e-28 98.4 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CEP07162.1 - 1.2e-05 24.8 0.1 2.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP07162.1 - 0.00044 19.9 2.9 0.005 16.5 0.1 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEP07163.1 - 1.4e-16 60.8 0.0 1.6e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain RT_RNaseH_2 PF17919.1 CEP07164.1 - 4.7e-37 126.0 0.0 9.7e-37 125.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP07164.1 - 8.7e-35 119.2 0.0 1.8e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP07164.1 - 0.00011 21.7 0.1 0.00024 20.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP07164.1 - 0.028 14.5 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain RVT_1 PF00078.27 CEP07165.1 - 8.7e-28 97.4 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neuroparsin PF07327.11 CEP07165.1 - 0.074 13.5 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Neuroparsin NDC10_II PF16787.5 CEP07166.1 - 0.075 12.1 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Patched PF02460.18 CEP07167.1 - 6.4e-83 279.2 12.7 7.6e-49 166.5 0.0 2.2 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 CEP07167.1 - 3.9e-73 246.0 4.2 5.6e-73 245.5 4.2 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CEP07167.1 - 9.8e-49 165.1 6.8 9.8e-49 165.1 6.8 3.2 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CEP07167.1 - 0.00018 20.6 4.9 0.00018 20.6 4.9 2.5 2 0 0 2 2 2 1 MMPL family Folate_rec PF03024.14 CEP07167.1 - 0.0014 18.5 4.6 0.03 14.2 0.7 2.4 2 0 0 2 2 2 2 Folate receptor family ACR_tran PF00873.19 CEP07167.1 - 0.039 11.6 17.7 0.078 10.6 17.7 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PRP38 PF03371.15 CEP07168.1 - 1.8e-59 200.6 0.4 2e-59 200.4 0.4 1.0 1 0 0 1 1 1 1 PRP38 family Cwf_Cwc_15 PF04889.12 CEP07169.1 - 2 8.1 13.0 2.6 7.7 13.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CEP07169.1 - 7 4.6 15.1 8 4.4 15.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi zf-RVT PF13966.6 CEP07172.1 - 0.00044 20.9 0.1 0.00082 20.0 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HECT PF00632.25 CEP07173.1 - 3.3e-97 325.7 0.0 6.1e-97 324.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 CEP07173.1 - 2e-90 303.5 4.4 2e-90 303.5 4.4 7.7 8 0 0 8 8 8 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CEP07173.1 - 9.4e-66 222.7 5.3 1e-43 150.2 1.4 7.7 7 1 1 8 8 8 2 Domain of Unknown Function (DUF908) UBM PF14377.6 CEP07173.1 - 7e-19 66.6 8.2 6.3e-09 35.0 0.1 2.9 2 0 0 2 2 2 2 Ubiquitin binding region UBA PF00627.31 CEP07173.1 - 1.9e-10 40.5 0.4 4.8e-10 39.1 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain BUD22 PF09073.10 CEP07173.1 - 0.0015 18.0 2.4 0.0015 18.0 2.4 7.7 6 2 1 8 8 8 1 BUD22 RhoGAP PF00620.27 CEP07174.1 - 2.7e-34 118.2 0.0 4.9e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ATP-synt_E PF05680.12 CEP07175.1 - 6.1e-17 61.8 0.2 1.1e-16 60.9 0.2 1.4 1 0 0 1 1 1 1 ATP synthase E chain RhoGAP PF00620.27 CEP07176.1 - 1.3e-44 151.7 0.5 3.5e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CEP07176.1 - 6.5e-11 42.4 0.0 2.1e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PriCT_1 PF08708.11 CEP07176.1 - 0.042 13.6 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Apt1 PF10351.9 CEP07177.1 - 6.4e-128 427.6 2.4 6.4e-128 427.6 2.4 4.4 5 1 0 5 5 5 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 CEP07177.1 - 1.3e-116 390.3 4.6 1.3e-116 390.3 4.6 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 CEP07177.1 - 4.5e-39 134.1 0.0 1.5e-38 132.3 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CEP07177.1 - 1.5e-35 122.5 0.0 4.3e-35 120.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CEP07177.1 - 8.3e-30 103.5 1.5 5.5e-29 100.9 0.1 3.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Syd PF07348.12 CEP07178.1 - 0.0021 17.8 0.5 0.0046 16.6 0.5 1.5 1 0 0 1 1 1 1 Syd protein (SUKH-2) RNase_E_G PF10150.9 CEP07178.1 - 0.0045 16.4 0.4 0.0045 16.4 0.4 1.5 2 0 0 2 2 2 1 Ribonuclease E/G family FYVE PF01363.21 CEP07180.1 - 4.5e-20 71.6 7.9 4.5e-20 71.6 7.9 2.9 3 0 0 3 3 3 1 FYVE zinc finger FYVE_2 PF02318.16 CEP07180.1 - 0.013 15.7 9.5 0.27 11.5 9.9 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger Lin-8 PF03353.15 CEP07180.1 - 0.11 12.1 7.3 0.17 11.4 7.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zn-C2H2_12 PF18112.1 CEP07180.1 - 0.14 12.7 3.8 4.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Macoilin PF09726.9 CEP07180.1 - 0.2 10.2 11.8 0.24 9.9 11.8 1.1 1 0 0 1 1 1 0 Macoilin family PSCyt3 PF07627.11 CEP07180.1 - 0.4 11.0 5.3 1.2 9.5 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1588) zf-RING_5 PF14634.6 CEP07180.1 - 0.65 10.0 15.9 17 5.5 9.9 3.6 3 1 0 3 3 3 0 zinc-RING finger domain GREB1 PF15782.5 CEP07180.1 - 5.4 4.0 15.2 6.9 3.6 15.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1387 PF07139.11 CEP07180.1 - 5.9 6.5 9.9 11 5.7 9.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PilJ PF13675.6 CEP07182.1 - 0.004 17.2 0.0 0.005 16.9 0.0 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term Sec39 PF08314.11 CEP07184.1 - 0.0067 14.9 0.0 0.008 14.7 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Cyt_bd_oxida_II PF02322.15 CEP07184.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II BAR_2 PF10455.9 CEP07185.1 - 4.8e-53 180.2 5.1 1.6e-52 178.5 5.1 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CEP07185.1 - 2.4e-23 83.0 4.9 1.1e-22 80.9 4.9 1.8 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CEP07185.1 - 1.3e-06 28.3 3.7 9.5e-06 25.5 0.2 2.7 1 1 1 3 3 3 1 BAR domain of APPL family Spectrin PF00435.21 CEP07185.1 - 0.0036 17.8 2.6 1.4 9.5 0.1 2.6 2 1 0 2 2 2 2 Spectrin repeat Serine_rich PF08824.10 CEP07185.1 - 0.0053 16.8 3.1 0.69 9.9 0.6 2.6 2 1 0 2 2 2 2 Serine rich protein interaction domain GIT1_C PF12205.8 CEP07185.1 - 0.051 13.7 0.5 0.29 11.3 0.0 2.3 1 1 1 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Vel1p PF10339.9 CEP07185.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Yeast-specific zinc responsive Med9 PF07544.13 CEP07185.1 - 0.11 12.6 2.3 6.5 6.9 0.1 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CHDCT2 PF08074.11 CEP07185.1 - 0.25 11.5 3.3 1.7 8.8 0.2 2.5 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain MIF4G_like_2 PF09090.11 CEP07185.1 - 0.63 9.5 4.2 0.78 9.2 1.1 2.2 2 0 0 2 2 2 0 MIF4G like PhaP_Bmeg PF09602.10 CEP07185.1 - 0.72 9.8 5.4 4.3 7.3 0.0 3.4 3 1 1 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Syntaxin_2 PF14523.6 CEP07185.1 - 0.74 10.2 6.6 0.87 10.0 0.6 3.0 2 1 1 3 3 3 0 Syntaxin-like protein IZUMO PF15005.6 CEP07185.1 - 1.1 9.8 3.3 2.2 8.8 0.4 2.5 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Laminin_II PF06009.12 CEP07185.1 - 2.5 8.1 8.3 6 6.9 0.7 2.9 2 1 1 3 3 3 0 Laminin Domain II FliD_N PF02465.18 CEP07185.1 - 2.9 8.6 9.3 0.9 10.3 0.5 3.5 2 2 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF2203 PF09969.9 CEP07185.1 - 6.9 7.4 6.1 34 5.2 0.7 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4799 PF16056.5 CEP07186.1 - 0.014 14.6 1.6 2.1 7.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4799) KH_8 PF17903.1 CEP07187.1 - 1.8e-30 104.9 0.4 5.6e-30 103.3 0.0 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 CEP07187.1 - 0.00081 19.2 0.0 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CEP07187.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 KH domain AAR2 PF05282.11 CEP07188.1 - 6.8e-94 315.2 0.0 1e-93 314.6 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Atypical_Card PF18461.1 CEP07188.1 - 0.039 14.2 0.1 0.098 12.9 0.1 1.6 1 0 0 1 1 1 0 Atypical caspase recruitment domain Alk_phosphatase PF00245.20 CEP07189.1 - 2.8e-101 339.5 0.1 3.4e-101 339.2 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CEP07189.1 - 0.05 13.0 0.8 0.085 12.2 0.2 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily WD40 PF00400.32 CEP07191.1 - 7e-12 45.7 16.7 0.0019 19.0 1.0 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat F-box-like PF12937.7 CEP07191.1 - 9.6e-08 31.8 0.3 2.3e-07 30.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07191.1 - 7.9e-07 28.8 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CEP07191.1 - 0.011 16.0 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_34 PF11312.8 CEP07191.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Herpes_capsid PF06112.11 CEP07191.1 - 0.98 9.5 6.2 13 5.8 6.2 2.4 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.25 CEP07192.1 - 5.3e-16 58.8 0.1 5e-11 42.5 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07192.1 - 3.1e-10 39.8 0.2 1.5e-06 27.7 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CEP07192.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP07192.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mucin PF01456.17 CEP07192.1 - 0.78 9.7 9.8 1.9 8.5 9.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UCH PF00443.29 CEP07193.1 - 1.7e-30 106.3 3.6 1.7e-30 106.3 3.6 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP07193.1 - 2.6e-18 66.7 5.6 2.6e-18 66.7 5.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase APC_u9 PF16633.5 CEP07193.1 - 0.87 10.7 4.7 4.9 8.3 1.3 2.9 2 0 0 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions Dermcidin PF15291.6 CEP07194.1 - 0.11 13.0 0.3 0.41 11.2 0.1 2.0 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide bZIP_1 PF00170.21 CEP07194.1 - 0.12 12.4 6.7 0.67 10.1 6.7 2.3 1 0 0 1 1 1 0 bZIP transcription factor FAM163 PF15069.6 CEP07194.1 - 0.21 12.0 2.4 1.6 9.1 0.3 2.5 2 0 0 2 2 2 0 FAM163 family KxDL PF10241.9 CEP07194.1 - 0.24 11.7 12.9 1.1 9.6 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Cnn_1N PF07989.11 CEP07194.1 - 0.26 11.4 11.6 0.046 13.9 5.3 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 CEP07194.1 - 1.3 9.2 11.5 0.12 12.4 5.0 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF572 PF04502.13 CEP07194.1 - 5.3 6.6 16.2 11 5.5 16.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) NST1 PF13945.6 CEP07195.1 - 8.3e-54 182.6 11.6 8.3e-54 182.6 11.6 3.7 3 1 2 5 5 5 1 Salt tolerance down-regulator bZIP_1 PF00170.21 CEP07196.1 - 4.8e-07 29.8 8.3 4.8e-07 29.8 8.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor UPF0242 PF06785.11 CEP07196.1 - 0.007 16.5 3.8 0.0097 16.0 3.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF2972 PF11186.8 CEP07196.1 - 0.0085 16.0 0.3 0.01 15.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2972) TTKRSYEDQ PF10212.9 CEP07196.1 - 0.009 15.1 1.6 0.011 14.7 1.6 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Herpes_UL6 PF01763.16 CEP07196.1 - 0.014 14.0 1.6 0.015 13.9 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc24 PF08286.11 CEP07196.1 - 0.028 14.6 0.8 0.051 13.8 0.8 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 GAS PF13851.6 CEP07196.1 - 0.03 13.7 6.5 0.025 13.9 5.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CEP07196.1 - 0.032 14.2 2.5 0.062 13.3 2.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Glutaredoxin2_C PF04399.13 CEP07196.1 - 0.065 13.1 3.6 0.08 12.8 1.1 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF4972 PF16342.5 CEP07196.1 - 0.067 12.9 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) bZIP_2 PF07716.15 CEP07196.1 - 0.093 12.8 16.7 0.053 13.6 10.0 2.8 1 1 1 2 2 2 0 Basic region leucine zipper Telomere_reg-2 PF10193.9 CEP07196.1 - 0.095 13.2 1.2 0.15 12.5 1.2 1.4 1 0 0 1 1 1 0 Telomere length regulation protein DUF5494 PF17598.2 CEP07196.1 - 0.096 12.8 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5494) ADIP PF11559.8 CEP07196.1 - 0.22 11.6 11.4 0.32 11.1 11.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_Maf PF03131.17 CEP07196.1 - 0.23 12.0 9.2 0.092 13.3 6.3 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor Caskin-tail PF16632.5 CEP07196.1 - 1.9 9.0 5.8 8.7 6.8 0.1 2.9 3 0 0 3 3 3 0 C-terminal region of Caskin eRF1_2 PF03464.15 CEP07197.1 - 0.067 13.5 0.0 0.083 13.2 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 2 TTC5_OB PF16669.5 CEP07197.1 - 0.075 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain HTH_18 PF12833.7 CEP07197.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain RT_RNaseH_2 PF17919.1 CEP07198.1 - 1.2e-28 99.1 0.0 2.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP07198.1 - 4e-25 88.1 0.1 8.7e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP07198.1 - 1.6e-15 57.3 0.0 4.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP07198.1 - 8.7e-11 41.7 0.3 4.6e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP07198.1 - 8e-08 32.3 0.7 2.4e-07 30.8 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CEP07198.1 - 2.3e-07 30.6 0.6 5.4e-07 29.4 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP07198.1 - 0.0081 16.4 0.9 0.039 14.2 0.9 2.3 1 0 0 1 1 1 1 H2C2 zinc finger Retrotran_gag_2 PF14223.6 CEP07198.1 - 0.019 14.6 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.6 CEP07198.1 - 0.044 14.4 0.0 0.14 12.7 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP07198.1 - 0.066 13.9 0.0 0.44 11.2 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease Retrotrans_gag PF03732.17 CEP07198.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein Fungal_trans PF04082.18 CEP07199.1 - 2.1e-17 63.0 1.0 5.6e-17 61.6 1.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 CEP07200.1 - 2.1e-103 345.8 30.0 4.7e-57 193.7 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP07200.1 - 8.8e-55 185.0 0.3 6.1e-32 111.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP07200.1 - 1.1e-08 34.9 2.5 0.00023 20.7 0.2 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP07200.1 - 1e-07 32.3 1.7 0.021 15.1 0.5 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP07200.1 - 3.1e-07 30.9 1.1 0.015 15.7 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CEP07200.1 - 1.1e-06 28.1 0.2 0.046 13.0 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.20 CEP07200.1 - 1.3e-06 27.9 0.2 0.0081 15.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 CEP07200.1 - 2.2e-06 27.7 0.0 0.08 12.8 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CEP07200.1 - 8.9e-05 22.2 5.2 0.05 13.3 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CEP07200.1 - 0.00012 21.9 0.6 0.65 9.7 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CEP07200.1 - 0.00024 20.9 0.0 0.076 12.7 0.0 3.1 2 2 0 3 3 3 1 AAA ATPase domain ABC_ATPase PF09818.9 CEP07200.1 - 0.00048 19.0 0.2 0.0011 17.8 0.1 1.7 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF87 PF01935.17 CEP07200.1 - 0.0012 19.0 0.5 3.4 7.7 0.0 3.3 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_28 PF13521.6 CEP07200.1 - 0.0028 17.9 0.1 2.3 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP07200.1 - 0.0032 17.0 0.1 2.5 7.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CEP07200.1 - 0.0051 17.4 0.0 4.4 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CEP07200.1 - 0.0052 16.7 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 CEP07200.1 - 0.0071 16.5 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CEP07200.1 - 0.0075 16.2 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain DUF2207 PF09972.9 CEP07200.1 - 0.011 14.6 0.1 0.011 14.6 0.1 3.1 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) AAA_21 PF13304.6 CEP07200.1 - 0.012 15.5 0.1 4.5 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CEP07200.1 - 0.013 15.5 0.1 6.3 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEP07200.1 - 0.018 15.4 0.0 10 6.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 CEP07200.1 - 0.027 14.6 0.4 12 6.0 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase PRK PF00485.18 CEP07200.1 - 0.033 13.9 0.3 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 CEP07200.1 - 0.047 13.0 0.1 2.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 CEP07200.1 - 0.05 13.2 0.4 20 4.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 CEP07200.1 - 0.05 13.3 0.1 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 CEP07200.1 - 0.051 13.2 0.5 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 CEP07200.1 - 0.068 12.9 0.2 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 CEP07200.1 - 0.074 13.5 1.4 14 6.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 CEP07200.1 - 0.17 11.8 0.5 23 4.9 0.0 2.7 3 0 0 3 3 2 0 NACHT domain AAA_24 PF13479.6 CEP07200.1 - 0.18 11.5 2.5 12 5.5 0.2 2.9 3 1 0 3 3 2 0 AAA domain Helitron_like_N PF14214.6 CEP07201.1 - 1.8e-23 83.8 0.1 2.4e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cactin_mid PF10312.9 CEP07201.1 - 0.074 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin RVT_1 PF00078.27 CEP07203.1 - 1.7e-33 116.0 0.0 4.4e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP07203.1 - 5e-06 27.1 1.3 1.7e-05 25.5 1.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Methyltransf_PK PF05891.12 CEP07204.1 - 2e-77 259.6 0.1 2.4e-77 259.3 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CEP07204.1 - 8e-10 39.3 0.0 1.4e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP07204.1 - 4.7e-07 30.4 0.0 8.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP07204.1 - 7.9e-07 29.8 0.0 1.3e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP07204.1 - 3.8e-05 23.6 0.0 7.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP07204.1 - 0.001 18.7 0.0 0.0041 16.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CEP07204.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 CEP07204.1 - 0.0068 16.2 0.2 0.013 15.3 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEP07204.1 - 0.13 12.2 0.1 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain ABC_tran PF00005.27 CEP07205.1 - 3.3e-28 98.9 0.0 5.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEP07205.1 - 1e-07 32.1 0.1 0.00022 21.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP07205.1 - 9.1e-06 25.3 0.0 0.00015 21.3 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEP07205.1 - 4.8e-05 23.8 0.0 9.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEP07205.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Mg_chelatase PF01078.21 CEP07205.1 - 0.0015 17.9 0.0 0.047 13.1 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEP07205.1 - 0.0023 17.8 0.1 0.0076 16.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 CEP07205.1 - 0.005 16.5 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 CEP07205.1 - 0.0084 16.5 0.1 0.046 14.1 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CEP07205.1 - 0.0095 16.5 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP07205.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CEP07205.1 - 0.02 14.9 0.0 0.076 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CEP07205.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 CEP07205.1 - 0.023 14.9 0.0 0.72 10.1 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CEP07205.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP07205.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEP07205.1 - 0.047 14.0 0.0 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CEP07205.1 - 0.051 14.1 0.0 0.077 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEP07205.1 - 0.057 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEP07205.1 - 0.085 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CEP07205.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEP07205.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 CEP07205.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.6 CEP07205.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CEP07206.1 - 4.6e-53 180.3 0.1 8.3e-53 179.4 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07206.1 - 1.5e-19 70.3 0.0 3.4e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4476 PF14771.6 CEP07206.1 - 0.092 13.1 0.2 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) PepSY_TM_like_2 PF16357.5 CEP07206.1 - 0.14 12.1 0.3 0.23 11.4 0.3 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like RIO1 PF01163.22 CEP07206.1 - 0.18 11.4 0.6 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family TPR_MLP1_2 PF07926.12 CEP07207.1 - 0.0022 18.0 18.4 0.0022 18.0 18.4 5.3 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein Arm-DNA-bind_2 PF12167.8 CEP07207.1 - 0.1 12.6 1.4 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Ubiq_cyt_C_chap PF03981.12 CEP07207.1 - 0.49 10.5 11.9 0.057 13.5 0.9 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone DUF2277 PF10041.9 CEP07207.1 - 2.1 8.7 8.5 2.4 8.6 3.0 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) ApoO PF09769.9 CEP07207.1 - 4.8 7.2 14.2 3.1 7.7 2.0 3.5 3 1 0 4 4 4 0 Apolipoprotein O Rtf2 PF04641.12 CEP07208.1 - 6.3e-78 261.8 10.1 7.5e-78 261.5 10.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF935 PF06074.12 CEP07208.1 - 0.0011 17.9 3.6 0.0055 15.5 4.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF935) zf-Nse PF11789.8 CEP07208.1 - 0.0034 17.2 0.1 0.13 12.1 0.0 2.8 1 1 2 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit YhfH PF14149.6 CEP07208.1 - 0.0046 16.9 2.3 0.0069 16.3 0.4 2.1 1 1 1 2 2 2 1 YhfH-like protein DUF2256 PF10013.9 CEP07208.1 - 0.017 15.2 0.2 0.047 13.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RNase_PH_C PF03725.15 CEP07208.1 - 0.04 14.0 0.1 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 zf-NOSIP PF15906.5 CEP07208.1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Cellulose_synt PF03552.14 CEP07208.1 - 0.13 10.7 4.0 0.17 10.4 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase PRTP PF01366.18 CEP07208.1 - 0.36 8.8 4.7 0.6 8.1 4.7 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Molybdopterin PF00384.22 CEP07209.1 - 4.7e-70 236.7 0.0 2.8e-69 234.1 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CEP07209.1 - 4.7e-19 68.2 0.2 3e-18 65.7 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CEP07209.1 - 4.7e-16 58.0 0.2 4.7e-16 58.0 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 CEP07209.1 - 3.1e-14 53.4 0.3 7.5e-14 52.1 0.3 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 CEP07209.1 - 7.5e-08 32.2 0.3 7.5e-08 32.2 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF4108 PF13390.6 CEP07209.1 - 0.039 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) TPP_enzyme_M PF00205.22 CEP07209.1 - 0.064 13.0 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-H2C2_2 PF13465.6 CEP07210.1 - 4.2e-10 39.6 9.2 3.5e-08 33.5 0.1 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP07210.1 - 3.2e-09 36.8 7.4 7.9e-06 26.0 1.9 3.5 3 1 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP07210.1 - 9.2e-06 26.1 5.6 0.00044 20.9 1.5 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEP07210.1 - 0.00053 19.7 3.1 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CEP07210.1 - 0.00061 19.5 2.9 0.021 14.6 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 CEP07210.1 - 0.004 17.4 5.7 0.0076 16.5 5.7 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CEP07210.1 - 0.062 13.6 8.1 0.72 10.2 0.1 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding MMR_HSR1_C PF08438.10 CEP07210.1 - 0.091 13.3 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal zf-C2H2_2 PF12756.7 CEP07210.1 - 0.096 13.0 0.5 0.096 13.0 0.5 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 CEP07210.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.8 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger zf-CHY PF05495.12 CEP07210.1 - 0.99 9.9 12.1 1.3 9.6 0.8 2.3 1 1 1 2 2 2 0 CHY zinc finger Spt46 PF17734.1 CEP07210.1 - 3.5 7.4 9.8 19 4.9 6.1 3.0 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 Rad21_Rec8 PF04824.16 CEP07211.1 - 8.5e-07 28.2 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein JAB PF01398.21 CEP07212.1 - 5.7e-15 55.3 0.1 2.1e-14 53.5 0.1 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEP07212.1 - 0.00057 19.6 0.1 0.00091 19.0 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain BRCC36_C PF18110.1 CEP07212.1 - 0.00084 19.4 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain IP_trans PF02121.18 CEP07213.1 - 3.6e-93 311.7 4.1 4.7e-93 311.3 4.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein zf-HIT PF04438.16 CEP07214.1 - 2.3e-09 37.0 7.9 3.6e-09 36.3 7.9 1.3 1 0 0 1 1 1 1 HIT zinc finger Pox_A12 PF04651.13 CEP07214.1 - 0.013 15.6 0.6 0.078 13.0 0.6 2.0 2 0 0 2 2 2 0 Poxvirus A12 protein zf-MYST PF17772.1 CEP07214.1 - 0.41 10.3 5.4 1.1 8.9 5.4 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain PPR_2 PF13041.6 CEP07215.1 - 5.1e-68 225.1 9.6 2.3e-11 43.7 0.0 15.6 12 3 4 16 16 14 13 PPR repeat family PPR PF01535.20 CEP07215.1 - 1.1e-47 156.9 21.1 2.4e-05 24.3 0.1 18.6 21 0 0 21 21 21 10 PPR repeat PPR_3 PF13812.6 CEP07215.1 - 4.3e-37 126.0 10.8 4.6e-10 39.4 0.1 10.8 9 3 4 13 13 13 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP07215.1 - 1.5e-33 114.2 0.4 2.4e-06 27.1 0.0 12.7 14 0 0 14 14 14 8 PPR repeat PPR_long PF17177.4 CEP07215.1 - 4e-27 95.0 17.1 1.3e-09 37.7 0.1 7.7 3 2 5 8 8 8 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 CEP07215.1 - 2.9e-08 34.1 1.5 0.00014 22.2 0.1 4.6 5 1 0 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 CEP07215.1 - 1.8e-06 28.3 11.7 0.45 11.1 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP07215.1 - 0.018 15.3 9.6 16 5.9 0.1 6.5 6 2 1 7 7 6 0 Tetratricopeptide repeat mCpol PF18182.1 CEP07215.1 - 0.038 14.3 0.1 0.2 12.0 0.1 2.3 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Atx10homo_assoc PF09759.9 CEP07215.1 - 0.12 12.4 0.5 4.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF5344 PF17279.2 CEP07215.1 - 0.88 10.2 8.2 1.5 9.4 0.0 4.2 4 0 0 4 4 3 0 Family of unknown function (DUF5344) TPR_7 PF13176.6 CEP07215.1 - 1.1 9.4 10.8 31 4.9 0.0 6.4 9 0 0 9 9 8 0 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 CEP07217.1 - 9.1e-55 185.8 0.0 1.1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain ABC_tran_CTD PF16326.5 CEP07217.1 - 6.2e-05 23.2 1.4 0.00017 21.7 1.4 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain APG6_N PF17675.1 CEP07217.1 - 0.00059 20.4 0.5 0.00097 19.7 0.5 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF5082 PF16888.5 CEP07217.1 - 0.0032 17.7 0.6 0.02 15.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Lzipper-MIP1 PF14389.6 CEP07217.1 - 0.0036 17.6 0.6 0.0065 16.7 0.6 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Ax_dynein_light PF10211.9 CEP07217.1 - 0.0047 16.9 1.1 0.008 16.1 1.1 1.4 1 0 0 1 1 1 1 Axonemal dynein light chain Spc24 PF08286.11 CEP07217.1 - 0.0073 16.5 0.3 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 GAS PF13851.6 CEP07217.1 - 0.013 14.9 0.3 0.013 14.9 0.3 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NuA4 PF09340.10 CEP07217.1 - 0.017 15.0 0.1 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Spectrin PF00435.21 CEP07217.1 - 0.019 15.5 0.6 0.044 14.3 0.6 1.6 1 0 0 1 1 1 0 Spectrin repeat MAD PF05557.13 CEP07217.1 - 0.021 13.2 0.2 0.028 12.8 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 CEP07217.1 - 0.03 14.3 3.9 0.066 13.2 3.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 CEP07217.1 - 0.037 14.4 1.3 0.083 13.3 1.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 CEP07217.1 - 0.048 13.6 1.7 0.4 10.6 1.9 2.4 3 0 0 3 3 2 0 Prefoldin subunit DUF3287 PF11690.8 CEP07217.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Prefoldin_2 PF01920.20 CEP07217.1 - 0.051 13.5 1.1 0.051 13.5 1.1 1.6 2 0 0 2 2 1 0 Prefoldin subunit Tektin PF03148.14 CEP07217.1 - 0.055 12.2 1.5 0.075 11.8 0.5 1.6 2 0 0 2 2 2 0 Tektin family DivIC PF04977.15 CEP07217.1 - 0.056 13.2 1.2 0.12 12.2 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.22 CEP07217.1 - 0.084 13.1 2.3 0.18 12.0 2.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 CEP07217.1 - 0.11 12.5 1.0 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 FlxA-like protein bZIP_1 PF00170.21 CEP07217.1 - 0.11 12.6 2.6 0.22 11.6 2.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF1192 PF06698.11 CEP07217.1 - 0.14 12.3 1.6 0.27 11.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.10 CEP07217.1 - 0.14 12.4 4.6 0.64 10.3 0.9 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF4140 PF13600.6 CEP07217.1 - 0.18 12.3 0.3 0.33 11.4 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.6 CEP07217.1 - 0.4 10.8 1.4 0.81 9.8 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PXA PF02194.15 CEP07219.1 - 0.0014 18.7 1.7 0.0036 17.3 1.7 1.8 1 1 0 1 1 1 1 PXA domain Cep57_CLD_2 PF14197.6 CEP07219.1 - 0.15 12.2 7.7 0.47 10.6 7.7 2.0 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Methyltransf_29 PF03141.16 CEP07219.1 - 0.59 8.6 5.2 0.18 10.3 0.4 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ARGLU PF15346.6 CEP07219.1 - 0.59 10.0 20.1 0.16 11.8 14.5 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Tho2 PF11262.8 CEP07219.1 - 2.8 7.1 10.7 6.6 5.8 7.8 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4112 PF13430.6 CEP07220.1 - 1.7e-34 118.2 2.6 2.1e-34 117.9 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Syja_N PF02383.18 CEP07222.1 - 6.4e-55 186.7 0.0 1.6e-54 185.4 0.0 1.7 1 1 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CEP07222.1 - 1.4e-11 44.3 0.1 2.4e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CxC2 PF18803.1 CEP07223.1 - 6.3e-06 26.3 1.1 1.2e-05 25.4 1.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DDE_3 PF13358.6 CEP07223.1 - 1.1e-05 25.2 0.0 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease EI24 PF07264.11 CEP07224.1 - 1.3e-19 71.1 9.2 1.2e-17 64.7 9.2 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PUF PF00806.19 CEP07225.1 - 3.9e-22 76.6 0.1 0.0021 17.6 0.1 7.5 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CEP07225.1 - 0.00074 19.3 0.0 0.0022 17.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_38N PF01074.22 CEP07225.1 - 0.043 13.2 0.8 0.16 11.3 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 N-terminal domain Amidohydro_1 PF01979.20 CEP07227.1 - 1.9e-35 122.8 0.0 2.4e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP07227.1 - 3.3e-12 46.6 0.1 1.9e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family G6PD_C PF02781.16 CEP07228.1 - 1.1e-114 382.5 0.1 1.5e-114 382.1 0.1 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEP07228.1 - 1.3e-58 198.6 0.4 4.2e-58 196.9 0.0 2.0 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SANT_DAMP1_like PF16282.5 CEP07229.1 - 2.1e-32 111.1 8.1 4.7e-32 110.0 8.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 CEP07229.1 - 1.6e-07 31.3 3.7 2.5e-07 30.7 1.7 2.3 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DMAP1_like PF17024.5 CEP07229.1 - 0.00015 21.8 2.6 0.00045 20.3 0.2 2.7 3 0 0 3 3 3 1 Putative DMAP1-like Myb_DNA-bind_6 PF13921.6 CEP07229.1 - 0.0059 16.8 2.1 0.025 14.8 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Sec39 PF08314.11 CEP07230.1 - 7.9e-106 355.3 0.2 1e-105 354.9 0.2 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 INTS2 PF14750.6 CEP07231.1 - 1.2e-06 26.5 6.5 3.6e-06 24.9 6.5 1.6 1 1 0 1 1 1 1 Integrator complex subunit 2 PsaD PF02531.16 CEP07233.1 - 0.0015 18.1 3.9 3.5 7.2 0.1 3.4 3 0 0 3 3 3 3 PsaD DUF4141 PF13605.6 CEP07233.1 - 0.024 13.9 3.4 23 4.3 0.1 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4141) DUF4391 PF14335.6 CEP07233.1 - 0.034 13.9 1.4 11 5.6 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4391) DNA_pol_B_palm PF14792.6 CEP07233.1 - 0.32 11.2 15.4 15 5.8 1.2 5.2 2 1 4 6 6 6 0 DNA polymerase beta palm Sigma54_DBD PF04552.13 CEP07233.1 - 1.3 8.7 4.9 6.7 6.4 0.1 3.8 4 0 0 4 4 4 0 Sigma-54, DNA binding domain Emaravirus_P4 PF16505.5 CEP07234.1 - 0.00019 20.6 1.0 0.00049 19.2 0.1 1.9 2 0 0 2 2 2 1 P4 movement protein of Emaravirus, and the 30K superfamily Ge1_WD40 PF16529.5 CEP07234.1 - 0.0023 16.9 0.6 0.046 12.7 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CGGC PF08821.11 CEP07235.1 - 0.0085 16.3 1.7 0.016 15.4 1.7 1.5 1 0 0 1 1 1 1 CGGC domain Anillin_N PF16018.5 CEP07236.1 - 0.029 15.0 5.9 0.073 13.7 0.0 3.0 3 0 0 3 3 3 0 Anillin N-terminus DUF745 PF05335.13 CEP07236.1 - 0.27 11.0 4.3 0.78 9.4 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) BAR_2 PF10455.9 CEP07237.1 - 0.029 13.5 0.2 0.043 12.9 0.2 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Nop53 PF07767.11 CEP07238.1 - 0.0043 16.5 12.4 0.0043 16.5 12.4 2.3 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) VIT1 PF01988.19 CEP07238.1 - 0.92 9.3 5.0 1.8 8.3 5.0 1.5 1 0 0 1 1 1 0 VIT family LMBR1 PF04791.16 CEP07238.1 - 1.7 7.4 7.2 2.4 7.0 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 CEP07238.1 - 2 6.8 3.0 2.5 6.5 3.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bud13 PF09736.9 CEP07238.1 - 2.4 8.5 22.9 0.43 11.0 16.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Peptidase_S15 PF02129.18 CEP07238.1 - 2.4 7.7 12.4 0.34 10.5 8.1 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FapA PF03961.13 CEP07238.1 - 9 4.8 8.4 14 4.1 8.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Amidinotransf PF02274.17 CEP07239.1 - 1.3e-20 73.8 0.2 2.2e-18 66.4 0.2 2.0 1 1 0 1 1 1 1 Amidinotransferase Tfb5 PF06331.12 CEP07239.1 - 0.072 13.1 1.0 0.23 11.5 0.2 2.3 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 DUF2577 PF10844.8 CEP07239.1 - 0.089 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) TLD PF07534.16 CEP07240.1 - 8.2e-39 133.0 0.4 1.6e-38 132.0 0.4 1.5 1 0 0 1 1 1 1 TLD Rav1p_C PF12234.8 CEP07241.1 - 1.8e-190 634.6 2.6 1.3e-189 631.8 2.6 2.1 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 CEP07241.1 - 9.5e-09 35.8 14.8 5.8e-06 26.9 0.1 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07241.1 - 0.00015 21.9 0.1 0.02 15.2 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PGA2 PF07543.12 CEP07243.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 DUF4449 PF14613.6 CEP07243.1 - 3.9 7.6 8.2 2.5 8.2 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) HAD_2 PF13419.6 CEP07244.1 - 1.9e-16 60.7 0.0 2.7e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP07244.1 - 1.7e-10 41.5 0.0 2.8e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP07244.1 - 2.1e-05 24.5 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Sds3 PF08598.11 CEP07245.1 - 1.2e-08 35.2 28.9 5.5e-07 29.8 6.8 3.4 1 1 2 3 3 3 2 Sds3-like DUF868 PF05910.12 CEP07245.1 - 0.064 12.9 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) GN3L_Grn1 PF08701.11 CEP07245.1 - 8.5 6.6 16.0 0.033 14.3 3.0 3.2 3 0 0 3 3 3 0 GNL3L/Grn1 putative GTPase LRR_4 PF12799.7 CEP07246.1 - 7.7e-29 99.3 47.7 2.4e-08 34.1 2.2 6.9 4 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEP07246.1 - 1e-17 64.2 24.2 1.2e-08 34.7 11.3 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CEP07246.1 - 8.2e-14 51.1 41.1 0.0001 22.0 3.6 5.7 2 1 4 7 7 7 6 Leucine rich repeat Pallilysin PF18663.1 CEP07246.1 - 0.013 15.5 1.0 0.033 14.2 1.0 1.7 1 0 0 1 1 1 0 Pallilysin beta barrel domain Iwr1 PF08574.10 CEP07246.1 - 0.17 12.9 6.6 0.43 11.6 6.6 1.6 1 0 0 1 1 1 0 Transcription factor Iwr1 LRR_6 PF13516.6 CEP07246.1 - 1.5 9.1 26.7 4.2 7.7 0.3 7.7 7 1 1 8 8 8 0 Leucine Rich repeat ubiquitin PF00240.23 CEP07247.1 - 3.7e-25 87.5 1.3 5.6e-22 77.3 0.4 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEP07247.1 - 1.8e-10 40.5 0.5 4e-10 39.4 0.4 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CEP07247.1 - 0.0094 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CEP07247.1 - 0.011 16.2 0.1 0.014 15.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1940 PF09155.10 CEP07247.1 - 0.089 12.9 0.1 0.1 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Med19 PF10278.9 CEP07248.1 - 0.0054 16.7 0.3 0.0057 16.6 0.3 1.0 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 DUF2321 PF10083.9 CEP07250.1 - 0.14 11.8 0.6 0.29 10.7 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) ubiquitin PF00240.23 CEP07251.1 - 1.9e-67 223.0 8.1 1.1e-33 114.8 1.1 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEP07251.1 - 4.7e-32 109.6 9.2 4.7e-16 58.4 1.4 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEP07251.1 - 7.7e-11 42.3 3.0 0.00037 20.9 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CEP07251.1 - 4.1e-08 33.1 1.0 0.0033 17.3 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEP07251.1 - 2.7e-07 30.8 2.5 0.0079 16.5 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP07251.1 - 1.4e-06 28.4 0.4 0.072 13.2 0.1 2.7 1 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEP07251.1 - 2.4e-06 28.1 0.2 0.063 13.8 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CEP07251.1 - 0.00015 21.6 0.1 0.29 10.9 0.0 2.2 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain DUF1940 PF09155.10 CEP07251.1 - 0.00046 20.3 0.7 0.29 11.2 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1940) Ubiquitin_4 PF18036.1 CEP07251.1 - 0.0012 18.9 9.7 4.4 7.4 0.3 4.0 4 0 0 4 4 4 1 Ubiquitin-like domain DUF3861 PF12977.7 CEP07251.1 - 0.0062 16.7 0.5 2.4 8.4 0.1 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) Big_3_3 PF13750.6 CEP07251.1 - 0.037 13.7 0.0 8 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF493 PF04359.14 CEP07251.1 - 0.044 14.4 0.0 10 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 CEP07251.1 - 0.052 13.2 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain DUF2870 PF11069.8 CEP07251.1 - 0.053 13.9 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) CDC48_2 PF02933.17 CEP07251.1 - 0.056 13.2 2.1 4.9 7.0 0.2 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 ACT_5 PF13710.6 CEP07251.1 - 0.065 13.1 1.0 11 6.0 0.1 2.4 2 0 0 2 2 2 0 ACT domain ProRS-C_2 PF09181.10 CEP07251.1 - 0.095 12.8 0.6 11 6.2 0.1 2.2 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Plexin_cytopl PF08337.12 CEP07251.1 - 0.85 8.2 6.5 3 6.4 0.5 2.7 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.11 CEP07251.1 - 2.7 8.3 7.2 15 5.9 0.8 2.3 2 0 0 2 2 2 0 Tash protein PEST motif MFS_1 PF07690.16 CEP07252.1 - 2.8e-21 75.9 35.0 4.1e-21 75.3 35.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07252.1 - 6.8e-06 25.2 25.6 0.00022 20.2 9.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Phage_holin_5_1 PF06946.11 CEP07252.1 - 0.68 10.4 3.7 8.1 6.9 0.4 2.8 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Kinesin PF00225.23 CEP07253.1 - 4.4e-98 328.3 0.2 4.4e-98 328.3 0.2 4.3 3 2 0 3 3 3 1 Kinesin motor domain Ribosomal_L4 PF00573.22 CEP07253.1 - 8.7e-36 123.4 0.6 8.7e-36 123.4 0.6 2.4 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CEP07253.1 - 8.4e-28 96.2 6.2 1e-27 95.9 2.8 3.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Microtub_bd PF16796.5 CEP07253.1 - 1.9e-16 60.4 0.2 7.2e-15 55.2 0.1 5.6 7 1 0 7 7 7 2 Microtubule binding GlcNAc-1_reg PF18440.1 CEP07253.1 - 0.33 11.2 3.9 12 6.2 0.3 4.6 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain Homeobox_KN PF05920.11 CEP07254.1 - 6.5e-19 67.5 0.8 1.6e-18 66.3 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEP07254.1 - 1.7e-08 34.2 0.7 5.9e-08 32.4 0.7 2.0 1 0 0 1 1 1 1 Homeodomain DUF643 PF04867.12 CEP07254.1 - 0.076 13.6 0.1 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF3994 PF13159.6 CEP07254.1 - 0.11 13.1 0.1 0.38 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF3439 PF11921.8 CEP07254.1 - 0.8 9.7 7.8 0.41 10.6 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RhoGAP PF00620.27 CEP07255.1 - 5.3e-08 32.8 0.3 3.9e-07 30.0 0.1 2.5 2 1 0 2 2 2 1 RhoGAP domain TFIIA PF03153.13 CEP07255.1 - 0.48 10.4 28.7 0.71 9.8 28.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trypan_PARP PF05887.11 CEP07255.1 - 2.5 8.1 9.3 0.15 12.0 3.9 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Lin-8 PF03353.15 CEP07255.1 - 8.3 5.9 18.0 14 5.1 18.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Suf PF05843.14 CEP07256.1 - 3.3e-76 257.1 0.0 3.3e-76 257.1 0.0 6.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEP07256.1 - 8.2e-07 29.3 0.6 1.2 10.1 0.0 5.0 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP07256.1 - 0.00034 21.1 0.8 0.23 12.0 0.9 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP07256.1 - 0.0078 16.4 0.2 0.48 10.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP07256.1 - 0.036 14.7 0.9 32 5.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEP07256.1 - 0.059 13.8 0.4 24 5.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP07256.1 - 0.074 13.2 0.0 33 4.9 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1664 PF07889.12 CEP07256.1 - 1.3 9.1 5.6 5.6 7.0 5.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 CEP07256.1 - 7.2 5.1 9.6 0.23 10.0 3.1 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A rve PF00665.26 CEP07257.1 - 1.9e-14 53.9 0.0 3.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP07257.1 - 4.1e-11 42.6 1.3 1.4e-10 40.9 0.2 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.6 CEP07258.1 - 9.3e-29 100.1 0.0 1.4e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ricin_B_lectin PF00652.22 CEP07259.1 - 5.7e-42 143.0 24.3 5.3e-07 29.9 0.6 14.0 10 4 3 13 13 13 11 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEP07259.1 - 7.2e-21 74.7 35.2 0.0033 18.1 0.1 14.8 12 2 4 17 17 17 10 Ricin-type beta-trefoil lectin domain-like TB2_DP1_HVA22 PF03134.19 CEP07260.1 - 7.2e-15 54.7 1.9 2e-14 53.2 1.9 1.8 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Cyclin_N PF00134.23 CEP07260.1 - 3.5e-09 36.5 0.9 7.3e-09 35.4 0.9 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain SLM4 PF16818.5 CEP07260.1 - 0.019 15.0 0.2 0.066 13.2 0.2 2.0 1 0 0 1 1 1 0 Protein SLM4 Cyclin PF08613.11 CEP07260.1 - 0.019 15.3 0.7 0.046 14.1 0.0 2.0 2 0 0 2 2 2 0 Cyclin Cpn60_TCP1 PF00118.24 CEP07261.1 - 9.5e-17 60.8 0.0 1e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FlgD_ig PF13860.6 CEP07261.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 FlgD Ig-like domain M20_dimer PF07687.14 CEP07262.1 - 1.2e-10 41.3 0.0 4.9e-09 36.1 0.0 3.1 3 0 0 3 3 3 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CEP07262.1 - 0.00011 22.0 0.7 0.0002 21.1 0.3 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 PcfK PF14058.6 CEP07262.1 - 0.037 14.3 0.6 0.037 14.3 0.6 2.8 3 1 0 3 3 3 0 PcfK-like protein GTP_cyclohydroI PF01227.22 CEP07263.1 - 1.3e-76 256.0 0.4 1.6e-76 255.8 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CEP07263.1 - 9.2e-06 25.7 0.0 2.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein F-box-like PF12937.7 CEP07264.1 - 1.5e-05 24.8 1.1 2.3e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like Complex1_LYR PF05347.15 CEP07265.1 - 1.5e-08 34.5 0.2 2.3e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEP07265.1 - 1.4e-06 29.0 1.3 2.4e-06 28.2 1.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like RhoGEF PF00621.20 CEP07266.1 - 1.4e-34 120.0 1.7 1.4e-34 120.0 1.7 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 CEP07266.1 - 0.0031 18.0 0.1 0.015 15.8 0.1 2.2 1 0 0 1 1 1 1 PH domain Cauli_AT PF03233.13 CEP07266.1 - 7.1 6.5 8.1 2.3 8.1 0.1 3.2 4 0 0 4 4 4 0 Aphid transmission protein Caleosin PF05042.13 CEP07267.1 - 1.5e-47 161.7 0.0 2.2e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Caleosin related protein ATPase_gene1 PF09527.10 CEP07267.1 - 0.17 12.1 2.3 0.3 11.3 2.3 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter LapA_dom PF06305.11 CEP07267.1 - 0.18 11.7 1.8 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RVT_1 PF00078.27 CEP07268.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Multi_Drug_Res PF00893.19 CEP07268.1 - 0.21 12.3 1.8 5.9 7.6 0.1 3.0 3 0 0 3 3 3 0 Small Multidrug Resistance protein DUF3324 PF11797.8 CEP07271.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) DNA_pol_A_exo1 PF01612.20 CEP07273.1 - 1.9e-11 44.0 0.0 2.9e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease MRP-L28 PF09812.9 CEP07274.1 - 2e-17 63.8 1.0 2.3e-17 63.6 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF241 PF03087.14 CEP07274.1 - 0.0022 17.9 0.5 0.0027 17.6 0.5 1.0 1 0 0 1 1 1 1 Arabidopsis protein of unknown function Aa_trans PF01490.18 CEP07276.1 - 1.8e-59 201.5 28.1 2.1e-59 201.3 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5579 PF17742.1 CEP07276.1 - 0.091 12.3 1.6 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5579) 7TMR-DISM_7TM PF07695.11 CEP07276.1 - 3.9 7.3 34.4 0.018 15.0 9.6 3.3 3 0 0 3 3 3 0 7TM diverse intracellular signalling Retrotrans_gag PF03732.17 CEP07277.1 - 0.015 15.5 0.6 0.044 14.1 0.1 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein NESP55 PF06390.12 CEP07277.1 - 8.1 6.0 9.0 28 4.2 6.0 2.2 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) RRM_1 PF00076.22 CEP07278.1 - 1e-14 54.1 0.0 1.5e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CEP07278.1 - 1.9e-07 30.9 4.3 3.1e-07 30.2 4.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEP07278.1 - 0.00049 19.7 2.6 0.00097 18.8 2.6 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger ProRS-C_1 PF09180.11 CEP07278.1 - 0.011 16.0 0.1 0.015 15.5 0.1 1.2 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal CSD PF00313.22 CEP07278.1 - 0.02 14.8 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain RRM_7 PF16367.5 CEP07278.1 - 0.026 14.7 0.0 0.29 11.3 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif zf-CCHC_2 PF13696.6 CEP07278.1 - 0.045 13.6 3.4 0.075 12.9 3.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Nup35_RRM_2 PF14605.6 CEP07278.1 - 0.099 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.6 CEP07278.1 - 0.18 11.8 1.1 0.36 10.8 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RhoGAP PF00620.27 CEP07280.1 - 4.6e-13 49.2 0.2 2.8e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CEP07280.1 - 2e-12 47.2 0.1 2.7e-11 43.6 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 CEP07280.1 - 8.1e-07 29.0 0.0 2.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BAR PF03114.18 CEP07280.1 - 6.6e-06 25.9 2.3 6.6e-06 25.9 2.3 2.4 2 0 0 2 2 2 1 BAR domain PIN_8 PF18476.1 CEP07280.1 - 0.018 14.9 1.3 0.018 14.9 1.3 3.0 3 0 0 3 3 3 0 PIN like domain Herpes_ori_bp PF02399.15 CEP07280.1 - 0.021 12.9 0.1 0.033 12.2 0.1 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Glutaminase PF04960.15 CEP07280.1 - 0.077 12.2 0.2 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Glutaminase DUF29 PF01724.16 CEP07280.1 - 0.18 12.0 1.6 0.5 10.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF29 DUF2524 PF10732.9 CEP07280.1 - 0.23 11.8 4.6 0.41 11.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) BAR_3 PF16746.5 CEP07280.1 - 2.5 7.7 10.8 0.076 12.7 2.9 2.2 2 0 0 2 2 2 0 BAR domain of APPL family DUF1351 PF07083.11 CEP07280.1 - 3.1 7.5 11.0 0.14 11.9 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1351) TMPIT PF07851.13 CEP07280.1 - 4.7 6.4 6.0 0.43 9.8 0.4 2.0 2 0 0 2 2 2 0 TMPIT-like protein T3SSipB PF16535.5 CEP07280.1 - 4.9 7.6 16.0 0.43 11.0 1.1 3.5 3 0 0 3 3 3 0 Type III cell invasion protein SipB CBFD_NFYB_HMF PF00808.23 CEP07281.1 - 4e-13 49.4 0.0 9.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 CEP07281.1 - 0.0061 16.0 14.0 0.0059 16.0 14.0 1.1 1 0 0 1 1 1 1 BUD22 Histone PF00125.24 CEP07281.1 - 0.024 15.0 4.4 0.026 14.9 0.0 2.5 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SAPS PF04499.15 CEP07281.1 - 0.03 13.1 0.1 0.03 13.1 0.1 2.0 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 CEP07281.1 - 0.45 9.9 13.5 0.52 9.7 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop16 PF09420.10 CEP07281.1 - 0.59 10.1 12.0 0.77 9.8 12.0 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 RNA_pol_3_Rpc31 PF11705.8 CEP07281.1 - 1.6 8.9 21.4 2.4 8.4 21.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 CEP07281.1 - 2.1 6.5 22.7 2.3 6.3 22.7 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 CEP07281.1 - 4 6.7 18.0 5.2 6.3 18.0 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 CEP07281.1 - 6.2 6.1 29.1 7.8 5.8 29.1 1.1 1 0 0 1 1 1 0 SDA1 GST_N_3 PF13417.6 CEP07282.1 - 1.7e-19 70.0 0.1 3.1e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP07282.1 - 1.2e-18 67.2 0.2 2.2e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP07282.1 - 1.7e-14 53.9 0.0 3.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP07282.1 - 1e-08 35.3 0.0 4.5e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP07282.1 - 0.018 15.2 0.0 0.039 14.2 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP07282.1 - 0.03 14.3 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CEP07282.1 - 0.058 13.7 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Glutaredoxin PF00462.24 CEP07282.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin SapB_1 PF05184.15 CEP07282.1 - 5.9 7.0 7.5 5.3 7.2 0.1 3.3 3 1 1 4 4 4 0 Saposin-like type B, region 1 Vps36_ESCRT-II PF11605.8 CEP07283.1 - 0.0027 17.8 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Peptidase_M1 PF01433.20 CEP07285.1 - 2.5e-83 278.9 3.8 2.5e-83 278.9 3.8 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CEP07285.1 - 4.1e-70 236.8 2.9 4.2e-69 233.5 0.8 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CEP07285.1 - 3e-52 177.5 0.1 5.4e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminotran_1_2 PF00155.21 CEP07285.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II DDE_Tnp_1_7 PF13843.6 CEP07286.1 - 1.5e-05 24.4 0.4 2.4e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Transposase IS4 Pyr_redox_2 PF07992.14 CEP07287.1 - 8.7e-49 166.3 0.0 1.1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP07287.1 - 3.5e-11 43.5 0.0 1.5e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP07287.1 - 0.00011 21.6 0.0 0.16 11.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP07287.1 - 0.2 10.3 0.6 1.6 7.3 0.0 2.1 1 1 1 2 2 2 0 HI0933-like protein Pex19 PF04614.12 CEP07288.1 - 1.5e-66 224.6 21.2 1.5e-66 224.6 21.2 1.7 2 0 0 2 2 2 1 Pex19 protein family ApoLp-III PF07464.11 CEP07288.1 - 0.032 14.3 0.6 0.082 13.0 0.6 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 CEP07288.1 - 0.076 11.0 0.7 0.13 10.2 0.7 1.2 1 0 0 1 1 1 0 Prominin YtxH PF12732.7 CEP07288.1 - 2.1 9.0 11.9 1.8 9.2 0.3 3.7 3 1 0 3 3 3 0 YtxH-like protein Reprolysin_4 PF13583.6 CEP07290.1 - 0.0088 15.7 0.2 0.018 14.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Ribosomal_L30_N PF08079.12 CEP07291.1 - 3.4e-18 65.6 18.5 1.5e-14 54.0 7.8 2.4 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CEP07291.1 - 1.2e-17 63.6 1.2 2.4e-17 62.6 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L14e PF01929.17 CEP07293.1 - 5.7e-29 100.4 4.4 9.8e-29 99.7 4.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CEP07293.1 - 0.0073 16.2 0.5 0.017 15.1 0.5 1.6 1 0 0 1 1 1 1 KOW motif UCH PF00443.29 CEP07294.1 - 1.2e-71 241.3 0.0 6.9e-69 232.2 0.1 3.5 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EST1_DNA_bind PF10373.9 CEP07294.1 - 2.3e-17 63.4 2.5 2.3e-17 63.4 2.5 2.9 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain UCH_1 PF13423.6 CEP07294.1 - 8.4e-11 42.0 9.2 1.2e-05 25.1 0.1 4.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase EST1 PF10374.9 CEP07294.1 - 3e-07 31.1 0.4 3e-07 31.1 0.4 3.9 2 1 0 2 2 2 1 Telomerase activating protein Est1 PIN_4 PF13638.6 CEP07294.1 - 4e-05 23.9 0.5 4e-05 23.9 0.5 3.9 5 0 0 5 5 5 2 PIN domain TPR_17 PF13431.6 CEP07294.1 - 0.066 13.6 0.0 0.29 11.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SlyX PF04102.12 CEP07294.1 - 2.8 8.6 6.8 1.8 9.2 0.8 3.2 3 0 0 3 3 3 0 SlyX SET PF00856.28 CEP07295.1 - 7.1e-18 65.6 0.1 7.1e-18 65.6 0.1 3.9 3 2 0 3 3 3 1 SET domain AWS PF17907.1 CEP07295.1 - 8.1e-10 38.6 10.6 8.1e-10 38.6 10.6 2.8 3 0 0 3 3 3 1 AWS domain SRI PF08236.11 CEP07295.1 - 3.1e-07 30.5 1.3 1.3e-06 28.5 1.3 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.26 CEP07295.1 - 6.9e-07 29.2 1.4 2.3e-06 27.5 1.4 1.9 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 CEP07295.1 - 0.0018 18.3 0.0 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RB_B PF01857.20 CEP07295.1 - 0.077 13.0 1.6 4.3 7.4 0.1 2.8 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain 2OG-FeII_Oxy_5 PF13759.6 CEP07296.1 - 0.012 16.0 0.2 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Hexokinase_2 PF03727.16 CEP07297.1 - 3.4e-74 249.3 0.0 5.4e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP07297.1 - 1.3e-50 172.1 0.0 1.8e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Oxysterol_BP PF01237.18 CEP07298.1 - 3e-61 207.3 3.6 2.9e-59 200.8 3.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein VPS9 PF02204.18 CEP07299.1 - 4.9e-30 103.8 0.2 1.8e-29 102.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CEP07299.1 - 1.2e-13 51.1 0.6 7.2e-13 48.6 0.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 CEP07299.1 - 0.0025 17.5 0.0 0.0085 15.8 0.0 1.9 1 0 0 1 1 1 1 CUE domain IFT20 PF14931.6 CEP07299.1 - 0.022 14.9 1.6 0.032 14.4 0.3 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 ING PF12998.7 CEP07299.1 - 0.13 12.8 2.5 0.45 11.1 2.5 2.0 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding CCDC106 PF15794.5 CEP07300.1 - 0.0035 17.1 10.0 0.0035 17.1 10.0 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 DUF1635 PF07795.11 CEP07300.1 - 0.89 9.4 15.3 0.076 12.9 10.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF4482 PF14818.6 CEP07300.1 - 3.6 8.4 18.5 0.52 11.2 11.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) Ndc1_Nup PF09531.10 CEP07300.1 - 5 5.7 14.0 0.52 8.9 9.2 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CCDC53 PF10152.9 CEP07300.1 - 5.8 7.3 16.9 6.8 7.1 11.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CoA_trans PF01144.23 CEP07301.1 - 0.15 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Coenzyme A transferase Phage_integrase PF00589.22 CEP07303.1 - 5e-08 32.9 0.7 5e-08 32.9 0.7 2.6 2 0 0 2 2 2 1 Phage integrase family ALAD PF00490.21 CEP07304.1 - 1.5e-126 421.9 0.0 1.8e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Exo_endo_phos PF03372.23 CEP07305.1 - 6.5e-08 32.4 0.2 1.1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA-synt_1b PF00579.25 CEP07306.1 - 3.6e-71 239.9 0.0 4.9e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.25 CEP07308.1 - 1.4e-62 211.5 0.7 1e-54 185.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07308.1 - 4.5e-37 127.8 0.0 1e-32 113.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP07308.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP07308.1 - 0.0036 16.7 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP07308.1 - 0.0092 14.8 0.9 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP07308.1 - 0.017 15.1 0.0 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_7 PF13499.6 CEP07308.1 - 0.082 13.4 1.1 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair UPF0154 PF03672.13 CEP07308.1 - 0.14 12.2 0.4 6.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) CENP-N PF05238.13 CEP07309.1 - 4.6e-20 72.3 0.4 1.1e-18 67.8 0.4 2.1 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Hist_deacetyl PF00850.19 CEP07310.1 - 5.1e-81 272.5 0.0 8.1e-81 271.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain MBT PF02820.18 CEP07310.1 - 0.057 13.8 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 mbt repeat CIAPIN1 PF05093.13 CEP07311.1 - 2.2e-29 101.9 4.5 5.4e-29 100.7 4.5 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1952 PF09189.10 CEP07311.1 - 0.0051 16.6 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1952) Pantoate_transf PF02548.15 CEP07312.1 - 4.1e-109 364.0 0.1 4.8e-109 363.7 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CEP07312.1 - 0.0027 17.2 0.5 0.0076 15.7 0.5 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase rve PF00665.26 CEP07313.1 - 4.7e-13 49.4 0.0 8.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP07313.1 - 1.4e-10 40.9 1.2 3.1e-10 39.8 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Minor_capsid_1 PF10665.9 CEP07314.1 - 0.085 13.1 0.3 0.14 12.4 0.3 1.5 1 1 0 1 1 1 0 Minor capsid protein SpecificRecomb PF10136.9 CEP07315.1 - 0.26 9.5 0.0 0.43 8.8 0.0 1.3 1 0 0 1 1 1 0 Site-specific recombinase Peptidase_A17 PF05380.13 CEP07316.1 - 0.034 14.2 1.0 0.054 13.5 0.6 1.4 1 1 0 1 1 1 0 Pao retrotransposon peptidase SHR-BD PF06650.12 CEP07317.1 - 1e-73 248.1 1.5 1.8e-71 240.7 0.5 3.2 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 CEP07317.1 - 1.8e-73 247.3 17.4 8e-72 241.8 1.1 6.6 6 0 0 6 6 6 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CEP07317.1 - 1.1e-72 243.6 4.9 3e-66 222.6 0.1 3.4 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 CEP07317.1 - 1.2e-72 244.2 0.3 1.2e-72 244.2 0.3 7.0 6 1 1 7 7 7 2 Repeating coiled region of VPS13 CASP_C PF08172.12 CEP07317.1 - 1.2e-40 139.5 10.1 1.3e-29 103.3 1.9 5.2 2 1 1 4 4 4 2 CASP C terminal Chorein_N PF12624.7 CEP07317.1 - 1.9e-36 124.7 0.1 1.9e-36 124.7 0.1 3.1 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CEP07317.1 - 1.7e-09 37.9 0.4 1e-08 35.4 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain LAGLIDADG_1 PF00961.19 CEP07317.1 - 8.5 7.4 7.4 32 5.5 1.0 4.5 3 0 0 3 3 3 0 LAGLIDADG endonuclease PPR_2 PF13041.6 CEP07318.1 - 4.3e-56 186.9 17.9 1.7e-11 44.1 0.1 8.5 3 1 5 8 8 8 8 PPR repeat family PPR_3 PF13812.6 CEP07318.1 - 5.2e-45 151.4 4.6 1.6e-10 40.9 0.0 5.7 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP07318.1 - 8.9e-38 127.7 2.9 1.1e-07 31.4 0.0 8.5 9 0 0 9 9 9 6 PPR repeat PPR PF01535.20 CEP07318.1 - 2e-36 121.7 10.0 3.8e-07 29.9 0.2 8.6 9 0 0 9 9 9 7 PPR repeat PPR_long PF17177.4 CEP07318.1 - 1.7e-22 79.9 2.6 1.8e-08 34.0 0.3 3.1 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 CEP07318.1 - 0.00041 20.8 6.2 1.3 9.4 0.0 5.2 3 3 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) Phage_ABA_S PF18066.1 CEP07318.1 - 0.015 15.9 1.6 0.51 11.1 0.1 3.1 3 1 0 3 3 3 0 Phage ABA sandwich domain BKACE PF05853.12 CEP07318.1 - 0.069 12.4 2.4 7.6 5.8 0.2 3.1 2 2 2 4 4 4 0 beta-keto acid cleavage enzyme DUF1779 PF08680.10 CEP07318.1 - 2.5 8.2 9.5 1.1 9.4 6.8 1.8 2 0 0 2 2 2 0 TATA-box binding RVT_1 PF00078.27 CEP07320.1 - 8.1e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP07321.1 - 8.7e-05 22.4 0.1 0.00022 21.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Phage_integrase PF00589.22 CEP07322.1 - 3e-05 23.9 0.3 7.3e-05 22.6 0.3 1.6 1 0 0 1 1 1 1 Phage integrase family FH2 PF02181.23 CEP07324.1 - 7.6e-86 288.6 4.2 7.6e-86 288.6 4.2 2.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CEP07324.1 - 5.7e-44 150.1 1.6 5.7e-44 150.1 1.6 3.6 2 1 1 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CEP07324.1 - 2.8e-28 98.7 6.7 3.7e-17 62.5 0.1 3.4 3 1 1 4 4 4 2 Diaphanous GTPase-binding Domain DNA_pack_N PF02500.15 CEP07324.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Flu_M1_C PF08289.11 CEP07324.1 - 0.07 13.4 0.4 0.22 11.7 0.4 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF4250 PF14056.6 CEP07324.1 - 8.8 6.4 6.9 1.6 8.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) RVT_1 PF00078.27 CEP07325.1 - 1.2e-36 126.3 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP07325.1 - 1.5e-05 24.8 0.4 4.1e-05 23.4 0.4 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CEP07325.1 - 0.004 17.8 0.8 0.017 15.8 0.0 2.5 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 CEP07325.1 - 0.023 14.8 1.2 0.069 13.3 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle GET2 PF08690.10 CEP07325.1 - 0.45 10.1 10.6 0.76 9.4 10.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 CDC45 PF02724.14 CEP07325.1 - 1.4 7.1 9.6 2.3 6.4 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein HTH_ABP1_N PF18107.1 CEP07326.1 - 7.9e-07 28.7 1.5 2e-06 27.4 1.5 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 CEP07326.1 - 2.4e-05 24.3 0.0 5.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Helitron_like_N PF14214.6 CEP07327.1 - 2.4e-43 148.6 0.0 2.9e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_int_SAM_4 PF13495.6 CEP07331.1 - 0.029 14.8 0.3 5.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain NDC10_II PF16787.5 CEP07332.1 - 7.9e-08 31.7 0.0 1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 SAGA-Tad1 PF12767.7 CEP07333.1 - 1.8e-49 168.7 0.0 2.2e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 CEP07333.1 - 0.015 15.1 0.1 0.07 12.9 0.0 2.0 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family CRAL_TRIO PF00650.20 CEP07334.1 - 2.3e-18 66.4 0.2 4.1e-18 65.6 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CstA PF02554.14 CEP07334.1 - 0.0062 15.5 0.3 1.3 7.8 0.1 2.1 2 0 0 2 2 2 2 Carbon starvation protein CstA DUF1967 PF09269.11 CEP07334.1 - 0.18 11.8 0.2 8.6 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) F-box-like PF12937.7 CEP07335.1 - 3.1e-06 27.0 1.1 1.4e-05 24.9 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP07335.1 - 0.042 13.7 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 F-box domain PI_PP_I PF18363.1 CEP07335.1 - 2.9 8.1 5.2 1.8 8.8 0.0 3.0 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain NOC3p PF07540.11 CEP07336.1 - 2.1e-28 98.6 0.3 2.1e-28 98.6 0.3 3.9 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.17 CEP07336.1 - 8.7e-18 64.9 0.1 8.7e-18 64.9 0.1 3.7 3 1 0 3 3 3 1 CBF/Mak21 family TRIQK PF15168.6 CEP07336.1 - 0.088 12.7 0.6 4.9 7.1 0.0 3.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Pkinase PF00069.25 CEP07337.1 - 5e-62 209.7 0.1 6.4e-62 209.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07337.1 - 5.6e-31 107.8 0.0 8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP07337.1 - 3.2e-06 26.7 0.0 1.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP07337.1 - 0.0036 16.1 0.3 0.007 15.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP07337.1 - 0.013 14.4 0.0 0.032 13.2 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Cons_hypoth698 PF03601.14 CEP07338.1 - 7.2e-35 120.3 14.9 8.7e-30 103.6 13.5 2.4 2 0 0 2 2 2 2 Conserved hypothetical protein 698 Glt_symporter PF03616.14 CEP07338.1 - 0.0025 16.5 12.3 0.0085 14.8 5.0 2.4 2 0 0 2 2 2 2 Sodium/glutamate symporter Statherin PF03875.13 CEP07340.1 - 0.26 11.4 4.5 0.42 10.7 4.5 1.3 1 0 0 1 1 1 0 Statherin F-box-like PF12937.7 CEP07341.1 - 3.1e-08 33.4 0.0 6.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07341.1 - 0.00055 19.7 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 CEP07341.1 - 0.12 12.8 21.0 2.4 8.7 0.2 6.6 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) CPSF_A PF03178.15 CEP07342.1 - 3e-91 306.1 0.0 7.3e-91 304.8 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 CEP07342.1 - 5.4e-33 114.4 0.0 2.2e-31 109.1 0.0 2.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S28e PF01200.18 CEP07342.1 - 3.1e-31 107.2 1.1 8.1e-31 105.8 1.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S28e CAV_VP3 PF04771.12 CEP07342.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein DUF3824 PF12868.7 CEP07342.1 - 0.33 11.6 4.6 1.2 9.7 4.6 2.0 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) LZ_Tnp_IS66 PF13007.7 CEP07342.1 - 7.3 7.5 8.0 3.7 8.4 1.3 2.8 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain OrfB_Zn_ribbon PF07282.11 CEP07343.1 - 2e-09 37.2 0.1 2e-09 37.2 0.1 3.0 3 0 0 3 3 3 1 Putative transposase DNA-binding domain UBA_e1_thiolCys PF10585.9 CEP07343.1 - 0.088 12.7 1.7 3.3 7.6 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site zf-CCHC PF00098.23 CEP07343.1 - 0.41 10.8 11.7 5.8 7.2 5.6 3.1 2 1 0 2 2 2 0 Zinc knuckle HypA PF01155.19 CEP07343.1 - 8.4 6.5 7.7 19 5.3 0.1 3.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Herpes_TK PF00693.18 CEP07345.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus FAR1 PF03101.15 CEP07345.1 - 0.08 13.7 0.2 0.17 12.6 0.2 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain NDUF_B4 PF07225.12 CEP07346.1 - 0.073 13.0 0.7 0.25 11.3 0.3 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Atg8 PF02991.16 CEP07347.1 - 5.2e-52 174.4 0.2 6e-52 174.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CEP07347.1 - 4.1e-07 30.3 0.0 5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PALP PF00291.25 CEP07349.1 - 2.3e-42 145.4 0.2 3.6e-42 144.8 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CEP07349.1 - 2.9e-14 53.3 0.0 4.7e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain Ribosomal_L2_C PF03947.18 CEP07349.1 - 1.7e-07 31.5 4.6 1.3e-06 28.6 0.5 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Glyco_tran_WecB PF03808.13 CEP07349.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DnaJ PF00226.31 CEP07350.1 - 9.1e-19 67.4 1.9 2.3e-18 66.1 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain TTL PF03133.15 CEP07351.1 - 3e-50 171.0 2.8 4e-50 170.6 2.8 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CEP07351.1 - 0.0047 16.2 0.0 0.11 11.7 0.0 2.4 2 1 0 2 2 2 1 YheC/D like ATP-grasp SIR2 PF02146.17 CEP07351.1 - 0.15 12.0 0.7 0.74 9.7 0.2 2.4 2 1 1 3 3 3 0 Sir2 family MFS_1 PF07690.16 CEP07352.1 - 9.1e-26 90.6 42.1 9.1e-26 90.6 42.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07352.1 - 7e-12 44.9 4.2 7e-12 44.9 4.2 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEP07352.1 - 1.7e-06 26.8 21.3 4.2e-06 25.5 21.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4181 PF13789.6 CEP07352.1 - 0.44 10.8 8.4 8.2 6.7 1.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) HOK_GEF PF01848.16 CEP07352.1 - 4.4 6.8 6.8 12 5.4 6.8 1.8 1 0 0 1 1 1 0 Hok/gef family zf-C2HC_2 PF13913.6 CEP07353.1 - 0.045 13.7 0.6 0.068 13.1 0.6 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF1922 PF09082.10 CEP07353.1 - 0.12 12.6 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) BTB_2 PF02214.22 CEP07354.1 - 1.7e-17 63.6 0.1 1e-07 32.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DUF1387 PF07139.11 CEP07354.1 - 0.033 13.9 9.5 0.058 13.1 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BTB PF00651.31 CEP07354.1 - 0.044 14.0 0.2 1.6 8.9 0.0 2.9 4 0 0 4 4 4 0 BTB/POZ domain TFIIA PF03153.13 CEP07354.1 - 0.081 12.9 16.0 0.18 11.7 16.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CEP07354.1 - 0.6 9.6 8.5 1.1 8.8 8.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CEP07354.1 - 0.72 8.5 6.0 0.9 8.1 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2367 PF10164.9 CEP07354.1 - 1.6 9.2 4.2 4.6 7.8 4.2 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Presenilin PF01080.17 CEP07354.1 - 2.7 6.7 6.5 4 6.1 6.5 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CEP07354.1 - 9 6.2 12.9 15 5.4 12.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HIG_1_N PF04588.13 CEP07355.1 - 1.5e-14 53.9 6.3 3e-14 53.0 6.3 1.5 1 1 0 1 1 1 1 Hypoxia induced protein conserved region FtsJ PF01728.19 CEP07356.1 - 1.1e-36 126.6 0.0 1.7e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TFIIA PF03153.13 CEP07356.1 - 0.00099 19.2 3.9 0.0013 18.8 3.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CEP07356.1 - 1.3 9.7 15.1 3.4 8.3 15.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_1 PF00515.28 CEP07357.1 - 2.7e-38 128.2 35.4 2.5e-08 33.4 0.2 8.7 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 CEP07357.1 - 2.5e-32 108.4 29.0 3.6e-05 23.5 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 CEP07357.1 - 2.3e-27 94.9 1.6 2.3e-27 94.9 1.6 3.0 3 0 0 3 3 3 1 DnaJ domain TPR_16 PF13432.6 CEP07357.1 - 3.9e-23 81.8 10.4 8e-09 36.0 0.7 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP07357.1 - 4.3e-21 74.3 24.0 1.3e-07 31.2 1.0 8.8 5 3 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 CEP07357.1 - 3e-17 62.9 20.7 0.0014 19.1 0.7 6.5 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 CEP07357.1 - 3.2e-14 53.0 24.6 0.001 19.3 0.1 7.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP07357.1 - 3.4e-14 51.8 21.7 0.031 14.5 0.2 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEP07357.1 - 1.4e-11 44.2 13.7 0.0035 18.0 0.1 8.2 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP07357.1 - 4.2e-10 39.3 33.0 0.018 15.4 0.4 8.7 9 1 0 9 9 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP07357.1 - 7.1e-08 32.6 21.4 0.0069 16.6 0.1 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEP07357.1 - 1.6e-07 31.4 6.7 0.0078 16.3 0.0 5.0 5 1 1 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP07357.1 - 2.9e-07 30.5 15.2 0.21 11.7 0.1 6.6 5 2 2 7 7 7 3 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 CEP07357.1 - 2.4e-06 27.1 4.4 1.4 8.3 0.0 4.2 1 1 3 5 5 5 4 MalT-like TPR region TPR_6 PF13174.6 CEP07357.1 - 5.1e-06 26.8 21.3 0.69 10.7 0.1 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEP07357.1 - 2.1e-05 24.2 22.0 0.04 13.8 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP07357.1 - 0.00048 20.0 16.8 0.26 11.4 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF5113 PF17140.4 CEP07357.1 - 0.026 14.3 9.9 0.031 14.1 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) Hypoth_Ymh PF09509.10 CEP07357.1 - 0.12 12.3 0.7 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) Alkyl_sulf_dimr PF14863.6 CEP07357.1 - 0.13 12.7 15.8 0.77 10.2 1.0 3.9 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation PPR_2 PF13041.6 CEP07357.1 - 0.17 12.1 0.9 11 6.3 0.0 4.0 5 0 0 5 5 4 0 PPR repeat family PPR PF01535.20 CEP07357.1 - 0.25 11.7 1.2 47 4.6 0.0 3.6 3 0 0 3 3 3 0 PPR repeat DUF3856 PF12968.7 CEP07357.1 - 0.35 10.9 6.4 13 5.8 0.2 5.0 3 2 3 6 6 6 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.12 CEP07357.1 - 0.4 10.7 24.2 0.29 11.2 0.8 7.2 8 1 1 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 CEP07357.1 - 0.69 10.0 22.8 0.066 13.3 1.1 5.5 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain FAT PF02259.23 CEP07357.1 - 1.1 8.4 13.6 0.13 11.4 6.7 2.3 1 1 0 2 2 2 0 FAT domain DUF3463 PF11946.8 CEP07360.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) IFN-gamma PF00714.17 CEP07360.1 - 0.037 13.9 0.3 0.072 12.9 0.3 1.4 1 0 0 1 1 1 0 Interferon gamma Myb_DNA-binding PF00249.31 CEP07361.1 - 0.0023 18.1 0.9 0.004 17.3 0.9 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP07361.1 - 0.0058 16.9 0.4 0.016 15.5 0.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aa_trans PF01490.18 CEP07362.1 - 2.3e-91 306.6 29.0 2.6e-91 306.3 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEP07362.1 - 2.1e-09 36.9 17.7 2.1e-09 36.9 17.7 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Polysacc_deac_1 PF01522.21 CEP07364.1 - 3.9e-30 104.3 0.1 6.9e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP07364.1 - 0.00073 18.8 0.1 0.0032 16.7 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolase family 57 DUF5593 PF18007.1 CEP07364.1 - 0.054 14.2 0.1 0.21 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) L51_S25_CI-B8 PF05047.16 CEP07365.1 - 2.4e-09 37.0 0.1 3.5e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.9 CEP07365.1 - 0.00083 19.5 0.1 0.55 10.4 0.0 2.4 2 0 0 2 2 2 2 39S ribosomal protein L53/MRP-L53 GET2 PF08690.10 CEP07366.1 - 4.1e-17 62.8 0.0 5.4e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 AD PF09793.9 CEP07367.1 - 2.2e-27 95.0 0.0 3.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 CEP07367.1 - 0.081 12.5 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Gemin6 protein Mito_carr PF00153.27 CEP07368.1 - 5e-59 196.2 5.8 2.9e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CEP07368.1 - 0.0006 20.0 0.1 1.7 8.9 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PrcB_C PF14343.6 CEP07368.1 - 0.24 11.5 1.4 7.5 6.8 0.1 3.0 3 0 0 3 3 3 0 PrcB C-terminal Aa_trans PF01490.18 CEP07369.1 - 3.4e-61 207.2 24.3 4e-61 206.9 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CEP07369.1 - 1.4e-08 34.0 32.3 3e-08 32.9 32.3 1.5 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_9_N PF15420.6 CEP07369.1 - 3.8 7.4 7.0 0.88 9.5 0.0 3.1 1 1 3 4 4 4 0 Alpha/beta-hydrolase family N-terminus RNase_P_p30 PF01876.16 CEP07370.1 - 8.2e-42 143.1 1.0 1.5e-41 142.2 1.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 PTS_IIB PF02302.17 CEP07370.1 - 0.055 14.2 0.6 16 6.3 0.0 3.1 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit SDA1 PF05285.12 CEP07370.1 - 6.1 6.2 13.3 8.2 5.7 13.3 1.1 1 0 0 1 1 1 0 SDA1 DDE_3 PF13358.6 CEP07372.1 - 5.7e-27 94.3 0.0 1.3e-26 93.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Ribosomal_L32p PF01783.23 CEP07374.1 - 0.001 19.2 12.4 0.019 15.2 4.7 3.3 3 1 0 3 3 3 2 Ribosomal L32p protein family zinc_ribbon_2 PF13240.6 CEP07374.1 - 0.034 13.9 10.4 2.3 8.0 0.2 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEP07374.1 - 0.073 12.5 10.3 1.3 8.5 0.1 4.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-CCHC PF00098.23 CEP07374.1 - 0.11 12.7 0.6 0.11 12.7 0.6 3.6 4 0 0 4 4 3 0 Zinc knuckle HypA PF01155.19 CEP07374.1 - 0.12 12.4 12.1 3.4 7.7 1.0 3.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 CEP07374.1 - 0.14 12.1 13.0 0.75 9.8 0.1 4.3 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 CEP07374.1 - 0.16 12.1 12.0 3.5 7.8 1.9 4.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CEP07374.1 - 0.25 11.8 7.9 13 6.4 0.4 4.1 3 2 0 3 3 3 0 Zinc-finger double domain DZR PF12773.7 CEP07374.1 - 0.3 11.1 13.9 3e+03 -1.6 13.9 3.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 CEP07374.1 - 0.31 10.9 10.2 1.8 8.4 0.3 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-RING_7 PF02591.15 CEP07374.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain YhfH PF14149.6 CEP07374.1 - 0.69 9.9 5.4 52 3.9 0.0 3.4 3 0 0 3 3 3 0 YhfH-like protein zinc-ribbons_6 PF07191.12 CEP07374.1 - 1.3 9.0 14.7 11 6.1 0.4 3.8 2 2 2 4 4 4 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.19 CEP07374.1 - 1.4 9.3 9.0 3.1 8.2 1.0 3.1 3 0 0 3 3 3 0 DnaJ central domain zf_UBZ PF18439.1 CEP07374.1 - 2.1 8.0 14.2 3.7 7.2 0.1 4.8 5 1 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 CEP07374.1 - 2.6 8.0 12.5 1.5 8.8 0.2 3.8 4 0 0 4 4 3 0 Nudix N-terminal zf-Di19 PF05605.12 CEP07374.1 - 3.6 8.0 13.2 12 6.2 1.1 4.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.22 CEP07374.1 - 3.6 7.5 13.8 2.9 7.9 0.1 4.2 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NOB1_Zn_bind PF08772.11 CEP07374.1 - 4.7 7.4 12.3 0.74 10.0 1.3 3.5 3 2 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PHD PF00628.29 CEP07374.1 - 9.2 6.2 14.9 22 5.0 1.7 4.4 3 2 1 4 4 4 0 PHD-finger zinc_ribbon_4 PF13717.6 CEP07374.1 - 9.4 6.3 13.1 3.3 7.7 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Gpr1_Fun34_YaaH PF01184.19 CEP07375.1 - 1.8e-73 246.6 15.8 2.1e-73 246.4 15.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glycos_transf_2 PF00535.26 CEP07376.1 - 0.087 12.6 0.1 0.31 10.8 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_47 PF01532.20 CEP07377.1 - 3.3e-130 435.0 0.5 3.9e-130 434.8 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RRM_1 PF00076.22 CEP07378.1 - 8.4e-19 67.2 0.0 1.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CEP07378.1 - 1.5e-06 28.7 7.9 1.5e-06 28.7 7.9 3.7 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.6 CEP07378.1 - 7.6e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CEP07378.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain tRNA_int_end_N2 PF12928.7 CEP07379.1 - 2.7e-06 27.5 0.0 5.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 CEP07379.1 - 0.00012 21.6 0.0 0.00046 19.8 0.0 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain zf-CCHC PF00098.23 CEP07380.1 - 1.3e-48 160.9 55.6 1.1e-07 31.6 2.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CEP07380.1 - 5.8e-11 42.0 38.7 0.28 10.9 0.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CEP07380.1 - 3.4e-08 33.3 43.6 0.067 13.2 1.0 7.1 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CEP07380.1 - 2.5e-06 27.1 43.4 0.091 12.5 1.2 7.3 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger PBP1_TM PF14812.6 CEP07380.1 - 4.1 7.8 11.8 0.65 10.4 7.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_3 PF13415.6 CEP07381.1 - 1.5e-14 53.9 10.0 0.00053 20.2 0.2 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP07381.1 - 1.5e-13 50.4 3.9 7.5e-06 25.8 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CEP07381.1 - 3.7e-13 49.2 9.1 0.002 18.1 0.0 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP07381.1 - 4.6e-13 48.9 6.3 0.011 16.0 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CEP07381.1 - 1.5e-11 43.6 3.6 0.026 14.1 0.2 6.1 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CEP07381.1 - 5.2e-08 32.6 1.6 0.56 10.3 0.0 5.7 5 1 0 5 5 5 2 Kelch motif ASC PF00858.24 CEP07381.1 - 0.0031 16.6 0.0 0.0031 16.6 0.0 2.5 3 0 0 3 3 3 1 Amiloride-sensitive sodium channel Romo1 PF10247.9 CEP07381.1 - 0.012 16.0 1.8 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 LRR_10 PF18805.1 CEP07381.1 - 0.041 13.5 0.2 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat DUF2371 PF10177.9 CEP07381.1 - 0.12 12.6 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Sugar_tr PF00083.24 CEP07382.1 - 8e-96 321.6 20.6 3.8e-95 319.4 20.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP07382.1 - 7.3e-32 110.6 44.7 6.8e-28 97.6 16.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 CEP07382.1 - 0.092 13.0 0.2 0.72 10.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.10 CEP07382.1 - 0.092 12.5 0.2 0.38 10.5 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 CEP07382.1 - 1.3 8.7 9.6 4.8 6.8 0.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF3487 PF11990.8 CEP07382.1 - 6.3 6.7 10.4 3.2 7.7 1.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Myb_Cef PF11831.8 CEP07383.1 - 6.3e-37 127.4 7.3 6.3e-37 127.4 7.3 3.9 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CEP07383.1 - 4.4e-23 81.2 5.1 1e-11 44.8 1.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP07383.1 - 2.1e-21 75.9 6.8 6.5e-14 51.9 3.6 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 CEP07383.1 - 0.021 14.7 0.3 0.54 10.1 0.0 3.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.8 CEP07383.1 - 0.41 10.8 2.5 2 8.5 0.2 3.0 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3348 PF11828.8 CEP07384.1 - 0.015 15.0 0.5 0.023 14.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF5082 PF16888.5 CEP07384.1 - 1.3 9.4 7.9 9.5 6.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) BAG PF02179.16 CEP07385.1 - 6.7e-16 58.5 1.1 6.7e-16 58.5 1.1 2.5 2 0 0 2 2 2 1 BAG domain Myb_DNA-binding PF00249.31 CEP07385.1 - 3.2e-11 43.2 1.5 7.4e-11 42.1 1.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP07385.1 - 9.5e-09 35.4 2.7 1.2e-08 35.0 0.5 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ubiquitin PF00240.23 CEP07385.1 - 0.00015 21.5 0.0 0.0005 19.8 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CEP07385.1 - 0.00022 21.6 0.0 0.00097 19.5 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin-like domain SLIDE PF09111.10 CEP07385.1 - 0.013 15.5 4.1 0.21 11.6 0.0 4.1 3 1 1 4 4 4 0 SLIDE Sulfotransfer_4 PF17784.1 CEP07386.1 - 2.6e-62 210.4 0.0 3e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEP07386.1 - 2e-05 25.1 0.2 0.00015 22.2 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family DUF413 PF04219.12 CEP07386.1 - 0.026 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF DUF236 PF03057.14 CEP07386.1 - 0.05 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 DUF236 repeat Paf1 PF03985.13 CEP07387.1 - 2.9e-46 158.4 2.5 3.5e-46 158.1 2.5 1.0 1 0 0 1 1 1 1 Paf1 Methyltr_RsmB-F PF01189.17 CEP07387.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F UPF0139 PF03669.13 CEP07388.1 - 9.6e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) p450 PF00067.22 CEP07389.1 - 5e-75 253.0 0.0 6.6e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4774 PF15999.5 CEP07389.1 - 0.098 12.5 0.8 0.22 11.4 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) MAGE PF01454.19 CEP07390.1 - 3.7e-47 160.8 2.2 6e-47 160.1 2.2 1.3 1 0 0 1 1 1 1 MAGE family Inhibitor_I71 PF12628.7 CEP07390.1 - 0.019 14.8 3.3 0.036 13.9 3.3 1.4 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor MID_MedPIWI PF18296.1 CEP07390.1 - 0.027 14.3 3.4 0.038 13.8 3.4 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Rhabdo_M1 PF03342.13 CEP07390.1 - 0.046 13.1 2.8 0.078 12.3 2.8 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Glyco_hydro_67N PF03648.14 CEP07390.1 - 0.05 13.9 1.2 0.085 13.1 1.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus RSN1_7TM PF02714.15 CEP07391.1 - 3.5e-60 203.6 32.8 2.5e-59 200.9 32.8 2.3 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP07391.1 - 7.5e-36 124.0 0.0 1.4e-35 123.1 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEP07391.1 - 4.9e-34 117.3 1.5 4.9e-34 117.3 1.5 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF1533 PF07550.11 CEP07391.1 - 0.11 12.4 0.1 0.34 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1533) AIF_C PF14721.6 CEP07392.1 - 7.5e-48 162.2 0.1 1.7e-47 161.1 0.1 1.6 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.14 CEP07392.1 - 3.7e-46 157.7 0.5 5.5e-46 157.1 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP07392.1 - 8e-14 52.0 4.9 1.1e-11 45.1 0.2 3.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP07392.1 - 1.3e-10 41.0 1.1 1.2e-09 37.9 0.6 2.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP07392.1 - 8.5e-08 32.1 4.5 0.0038 16.8 0.1 4.1 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CEP07392.1 - 8.3e-07 28.4 1.1 0.013 14.6 0.0 3.5 2 1 1 3 3 3 2 Lycopene cyclase protein Amino_oxidase PF01593.24 CEP07392.1 - 1.1e-06 28.3 2.1 0.00014 21.3 0.2 2.2 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CEP07392.1 - 1.3e-06 27.4 0.3 0.02 13.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 CEP07392.1 - 1.5e-06 28.3 3.6 0.034 14.2 0.2 4.4 4 1 1 5 5 5 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CEP07392.1 - 2.8e-06 26.7 0.2 0.0001 21.6 0.0 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CEP07392.1 - 0.048 12.5 3.1 12 4.6 0.1 3.1 2 1 1 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 CEP07392.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.22 CEP07392.1 - 0.11 13.4 0.5 1.3 9.9 0.1 2.6 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_8 PF13450.6 CEP07392.1 - 0.27 11.5 1.3 26 5.1 0.1 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FLgD_tudor PF13861.6 CEP07392.1 - 0.39 11.0 2.9 0.53 10.6 0.5 2.4 2 0 0 2 2 2 0 FlgD Tudor-like domain PUF PF00806.19 CEP07393.1 - 2e-68 222.4 13.5 5.4e-09 35.3 0.0 8.8 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Met_synt_B12 PF02965.17 CEP07393.1 - 7.9 5.9 9.9 0.26 10.7 2.8 2.1 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain DDE_3 PF13358.6 CEP07394.1 - 6e-07 29.3 0.0 2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.6 CEP07395.1 - 0.00034 20.6 0.2 0.0011 19.0 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP07395.1 - 0.00054 19.8 0.4 0.00059 19.7 0.4 1.3 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 CEP07395.1 - 0.0025 17.5 0.1 0.0079 16.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CEP07395.1 - 0.0049 17.1 0.1 0.014 15.6 0.0 1.8 2 1 0 2 2 2 1 Transposase HTH_28 PF13518.6 CEP07395.1 - 0.0062 16.6 0.1 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 CEP07395.1 - 0.0081 15.9 0.3 0.062 13.1 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain IF2_N PF04760.15 CEP07395.1 - 0.011 15.6 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Sigma70_r3 PF04539.16 CEP07395.1 - 0.046 13.8 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 HTH_32 PF13565.6 CEP07395.1 - 0.06 14.0 1.3 0.2 12.3 1.2 1.9 1 1 0 1 1 1 0 Homeodomain-like domain DUF3791 PF12668.7 CEP07395.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) UxuA PF03786.13 CEP07397.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) Complex1_LYR PF05347.15 CEP07398.1 - 0.029 14.4 3.4 0.4 10.8 0.8 2.6 3 0 0 3 3 3 0 Complex 1 protein (LYR family) ELYS PF13934.6 CEP07398.1 - 0.036 14.0 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex assembly RNase_J_C PF17770.1 CEP07398.1 - 0.17 12.9 0.8 0.78 10.8 0.2 2.3 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain LRR_4 PF12799.7 CEP07399.1 - 1.7e-10 41.0 7.0 7.4e-06 26.2 0.1 3.9 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP07399.1 - 3.2e-05 23.6 13.7 0.016 15.2 0.2 5.0 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 CEP07399.1 - 0.0012 18.7 0.5 0.0035 17.2 0.5 1.8 1 0 0 1 1 1 1 F-box-like DUF234 PF03008.14 CEP07399.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function LRR_1 PF00560.33 CEP07399.1 - 0.14 12.8 7.1 10 7.1 0.5 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 CEP07399.1 - 0.16 11.7 1.2 2.3 8.0 0.6 2.6 1 1 1 2 2 2 0 Leucine rich repeat Y_phosphatase3 PF13350.6 CEP07400.1 - 7.5e-54 183.1 0.0 1.2e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP07400.1 - 0.00044 19.9 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 CEP07400.1 - 0.00081 18.7 0.8 0.044 13.0 0.0 2.7 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP07400.1 - 0.0017 18.1 0.1 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP07400.1 - 0.011 16.3 0.2 0.21 12.1 0.0 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family DSPc PF00782.20 CEP07400.1 - 0.068 13.0 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Abhydrolase_2 PF02230.16 CEP07400.1 - 0.13 12.0 1.2 0.25 11.1 1.2 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase WD40 PF00400.32 CEP07401.1 - 1.4e-08 35.3 6.3 0.00033 21.4 0.3 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07401.1 - 3.1e-07 30.6 0.0 0.0023 18.2 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP07401.1 - 0.0052 15.8 0.0 0.014 14.3 0.0 1.6 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEP07401.1 - 0.044 13.7 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Osmo_CC PF08946.10 CEP07402.1 - 2.1 8.7 11.2 12 6.3 3.7 3.2 1 1 1 2 2 2 0 Osmosensory transporter coiled coil rve PF00665.26 CEP07403.1 - 6e-20 71.6 0.0 9.7e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP07403.1 - 5.3e-13 48.9 0.6 5.3e-13 48.9 0.6 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP07403.1 - 0.0014 18.8 0.1 0.0046 17.2 0.1 2.0 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CEP07403.1 - 0.002 17.9 0.1 0.006 16.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Sugarporin_N PF11471.8 CEP07404.1 - 2.8 8.0 6.7 1.2 9.1 1.8 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AAA_11 PF13086.6 CEP07406.1 - 1.2e-65 222.0 0.5 3.8e-65 220.3 0.5 2.0 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CEP07406.1 - 5e-62 209.1 0.0 1.2e-61 207.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 CEP07406.1 - 1.4e-61 208.7 12.5 2.3e-61 208.0 12.5 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 CEP07406.1 - 2.7e-11 43.6 0.4 1.8e-07 31.1 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 CEP07406.1 - 9.3e-11 42.3 0.0 4.2e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CEP07406.1 - 7.7e-09 35.5 0.5 4.9e-06 26.3 0.5 3.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CEP07406.1 - 0.001 19.1 0.1 0.0046 17.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP07406.1 - 0.0015 18.8 0.0 0.009 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CEP07406.1 - 0.011 15.6 0.1 0.28 11.0 0.0 2.9 2 0 0 2 2 2 0 Helicase DEAD PF00270.29 CEP07406.1 - 0.014 15.1 1.8 0.2 11.4 1.8 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 CEP07406.1 - 0.12 12.8 0.1 0.41 11.1 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CEP07406.1 - 0.19 11.0 0.7 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ogr_Delta PF04606.12 CEP07407.1 - 8.2 6.5 7.1 0.88 9.6 1.5 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 CEP07408.1 - 0.023 15.1 2.8 0.042 14.2 0.3 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-RING_7 PF02591.15 CEP07408.1 - 0.042 14.0 4.1 3.3 8.0 0.2 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain zf-C6H2 PF15801.5 CEP07408.1 - 0.053 13.8 1.6 0.86 10.0 0.1 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Mu-like_Com PF10122.9 CEP07408.1 - 0.067 12.6 0.3 0.58 9.7 0.2 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com HNH PF01844.23 CEP07408.1 - 0.12 12.6 3.4 9.8 6.5 0.3 3.3 3 0 0 3 3 3 0 HNH endonuclease Nmad5 PF18757.1 CEP07408.1 - 0.19 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 Zn-ribbon_8 PF09723.10 CEP07408.1 - 0.82 9.8 6.3 2.4 8.4 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_10 PF16588.5 CEP07408.1 - 3.6 7.4 14.2 3.9 7.3 3.5 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger Zn_Tnp_IS1595 PF12760.7 CEP07408.1 - 9.7 6.3 11.6 10 6.2 1.3 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain PIN_5 PF08745.11 CEP07409.1 - 0.015 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 PINc domain ribonuclease Lipase_GDSL PF00657.22 CEP07409.1 - 0.065 13.2 0.1 0.072 13.1 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ubie_methyltran PF01209.18 CEP07410.1 - 1.8e-79 266.3 0.2 7.5e-79 264.3 0.1 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Synaptobrevin PF00957.21 CEP07410.1 - 2.4e-30 104.1 0.9 2.4e-30 104.1 0.9 2.3 3 0 0 3 3 3 1 Synaptobrevin Methyltransf_11 PF08241.12 CEP07410.1 - 1.8e-12 47.8 0.3 5.5e-12 46.2 0.1 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP07410.1 - 1.6e-11 44.8 0.0 5.1e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP07410.1 - 1.1e-08 35.1 0.5 3.7e-08 33.3 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP07410.1 - 8.8e-08 32.2 0.7 1e-06 28.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP07410.1 - 1.6e-07 32.0 0.9 1.5e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEP07410.1 - 0.0037 16.8 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MCU PF04678.13 CEP07410.1 - 0.0077 16.3 1.9 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Methyltransf_8 PF05148.15 CEP07410.1 - 0.008 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase SUIM_assoc PF16619.5 CEP07410.1 - 0.077 13.1 6.4 0.17 11.9 6.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MscS_TM PF12794.7 CEP07410.1 - 0.096 11.5 5.7 0.34 9.7 5.7 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF5345 PF17280.2 CEP07410.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Melibiase PF02065.18 CEP07411.1 - 1.4e-12 47.2 0.1 2.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 CEP07411.1 - 2e-06 27.3 0.2 2.7e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Raffinose_syn PF05691.12 CEP07411.1 - 0.15 9.8 0.1 0.22 9.2 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 ACOX PF01756.19 CEP07412.1 - 2.5e-50 170.6 0.0 4.9e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CEP07412.1 - 8.7e-20 70.7 0.0 1.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CEP07412.1 - 5.1e-13 49.7 0.0 1.6e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CEP07412.1 - 1.2e-08 35.3 0.5 5.6e-08 33.1 0.5 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain KH_1 PF00013.29 CEP07413.1 - 1.3e-09 37.7 0.2 6.1e-06 26.0 0.0 2.9 2 1 0 2 2 2 2 KH domain SbcD_C PF12320.8 CEP07413.1 - 0.15 12.4 0.1 0.39 11.1 0.1 1.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Retrotran_gag_2 PF14223.6 CEP07415.1 - 0.00015 21.4 0.8 0.00042 20.0 0.8 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 CEP07415.1 - 0.0023 18.2 0.5 0.0067 16.7 0.5 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein GATA PF00320.27 CEP07415.1 - 0.18 11.5 2.5 0.48 10.1 2.5 1.7 1 0 0 1 1 1 0 GATA zinc finger HTH_28 PF13518.6 CEP07416.1 - 4.6e-07 29.9 0.0 5.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP07416.1 - 7.7e-07 29.0 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 CEP07416.1 - 7.2e-05 22.5 0.0 9.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Fe_dep_repress PF01325.19 CEP07416.1 - 0.00044 20.4 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain LZ_Tnp_IS481 PF13011.6 CEP07416.1 - 0.012 16.1 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MarR_2 PF12802.7 CEP07416.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_32 PF13565.6 CEP07416.1 - 0.014 16.0 0.0 0.045 14.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 CEP07416.1 - 0.025 14.7 1.5 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_27 PF13463.6 CEP07416.1 - 0.049 14.1 0.0 0.068 13.7 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Terminase_5 PF06056.12 CEP07416.1 - 0.054 13.4 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) PAX PF00292.18 CEP07416.1 - 0.064 13.2 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 'Paired box' domain TrmB PF01978.19 CEP07416.1 - 0.065 13.1 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 CEP07416.1 - 0.067 12.7 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.20 CEP07416.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 CEP07416.1 - 0.087 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Phage_antitermQ PF06530.12 CEP07416.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q zf-RVT PF13966.6 CEP07417.1 - 9.9e-08 32.6 0.8 2e-07 31.6 0.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Nuf2 PF03800.14 CEP07419.1 - 0.064 13.4 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Nuf2 family DUF3007 PF11460.8 CEP07420.1 - 0.025 14.8 0.6 0.057 13.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) STELLO PF03385.17 CEP07420.1 - 0.038 12.8 0.0 0.086 11.6 0.0 1.5 1 0 0 1 1 1 0 STELLO glycosyltransferases rve PF00665.26 CEP07421.1 - 2.4e-12 47.1 0.0 4.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP07421.1 - 4.3e-10 39.6 0.1 8.3e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP07421.1 - 1.1e-05 25.5 0.2 2.1e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF5045 PF16464.5 CEP07421.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5045) RT_RNaseH PF17917.1 CEP07422.1 - 4.9e-30 103.9 0.0 8.8e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP07422.1 - 2.2e-27 95.0 0.0 4.3e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP07422.1 - 1.6e-21 76.9 0.1 3.6e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP07422.1 - 3.2e-09 37.3 0.1 4e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP07422.1 - 8.5e-08 32.7 0.0 2.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP07422.1 - 0.0004 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3742 PF12553.8 CEP07423.1 - 0.67 10.1 2.2 2.4 8.3 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Sugar_tr PF00083.24 CEP07424.1 - 2.8e-104 349.5 29.2 4.6e-102 342.2 29.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP07424.1 - 9.4e-26 90.6 27.2 9.4e-26 90.6 27.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Glug PF07581.12 CEP07424.1 - 0.31 11.5 2.3 1.5 9.4 2.3 2.3 1 0 0 1 1 1 0 The GLUG motif Helitron_like_N PF14214.6 CEP07425.1 - 3e-32 112.4 0.1 3.6e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_3 PF13358.6 CEP07426.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Ribosomal_S17_N PF16205.5 CEP07427.1 - 1.1e-29 102.7 3.2 2.1e-29 101.7 3.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CEP07427.1 - 1.5e-27 95.4 0.2 2.6e-27 94.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF922 PF06037.11 CEP07427.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) GAS2 PF02187.17 CEP07428.1 - 1.2e-11 44.5 0.1 4.7e-11 42.6 0.1 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Cep57_CLD_2 PF14197.6 CEP07428.1 - 0.23 11.6 16.9 0.32 11.1 0.8 6.8 4 1 1 5 5 5 0 Centrosome localisation domain of PPC89 DUF2315 PF10231.9 CEP07428.1 - 7 6.8 8.0 27 4.9 0.2 4.0 3 0 0 3 3 3 0 Apoptogenic protein 1 HAGH_C PF16123.5 CEP07429.1 - 8e-22 77.6 0.1 1.5e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEP07429.1 - 6.3e-13 49.2 0.8 1.2e-11 45.0 0.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP07429.1 - 0.00095 18.7 0.6 0.013 15.0 0.6 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP07429.1 - 0.0056 16.6 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA PF00004.29 CEP07430.1 - 5.4e-23 81.9 0.0 1.8e-22 80.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEP07430.1 - 2.7e-12 47.0 0.4 4.7e-12 46.3 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 CEP07430.1 - 1.4e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CEP07430.1 - 5.3e-05 22.8 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CEP07430.1 - 6.3e-05 23.4 0.0 0.00025 21.5 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 CEP07430.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEP07430.1 - 0.00022 21.5 1.0 0.029 14.6 0.0 3.1 3 1 1 4 4 3 1 AAA domain DUF815 PF05673.13 CEP07430.1 - 0.00041 19.6 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEP07430.1 - 0.0014 19.2 0.0 0.0053 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP07430.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEP07430.1 - 0.0021 18.4 1.6 0.022 15.2 0.0 2.9 3 0 0 3 3 2 1 RNA helicase ATPase PF06745.13 CEP07430.1 - 0.0036 16.7 0.0 0.012 14.9 0.0 1.9 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 CEP07430.1 - 0.0056 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEP07430.1 - 0.015 15.8 0.2 0.045 14.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 CEP07430.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CEP07430.1 - 0.023 15.1 0.1 0.093 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_34 PF13872.6 CEP07430.1 - 0.026 13.4 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Parvo_NS1 PF01057.17 CEP07430.1 - 0.031 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CEP07430.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEP07430.1 - 0.052 13.3 0.9 0.18 11.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 CEP07430.1 - 0.057 13.4 0.0 0.18 11.8 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.14 CEP07430.1 - 0.065 11.1 0.0 0.094 10.6 0.0 1.3 1 0 0 1 1 1 0 Helicase MMR_HSR1 PF01926.23 CEP07430.1 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CEP07430.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEP07430.1 - 0.13 12.3 0.0 0.96 9.5 0.0 2.4 1 1 2 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 CEP07430.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region HMG_box PF00505.19 CEP07431.1 - 4.1e-13 49.6 1.1 1.2e-12 48.0 0.1 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box SAM_1 PF00536.30 CEP07431.1 - 9.7e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 CEP07431.1 - 2.9e-09 37.4 0.2 1e-08 35.6 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 CEP07431.1 - 3.2e-07 30.3 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HTH_23 PF13384.6 CEP07431.1 - 2.6e-05 23.9 0.9 0.0038 17.0 0.1 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.6 CEP07431.1 - 7.7e-05 23.2 0.0 0.00027 21.5 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP07431.1 - 0.00049 20.2 0.7 0.0018 18.3 0.7 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain NCD1 PF04904.13 CEP07431.1 - 0.00059 19.8 0.1 0.014 15.4 0.0 2.6 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) HTH_29 PF13551.6 CEP07431.1 - 0.0014 18.6 0.8 0.006 16.6 0.3 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP07431.1 - 0.0019 17.6 0.3 0.038 13.4 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 CEP07431.1 - 0.11 12.7 0.3 5.1 7.4 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DNA_pol_phi PF04931.13 CEP07431.1 - 1.4 6.9 6.3 0.095 10.8 0.5 1.8 2 0 0 2 2 2 0 DNA polymerase phi DEAD PF00270.29 CEP07432.1 - 3.8e-45 153.8 0.0 1.2e-43 149.0 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP07432.1 - 1.1e-29 103.0 0.0 6.6e-29 100.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP07432.1 - 9.4e-08 32.2 0.0 4.7e-06 26.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 CEP07432.1 - 0.0012 18.8 2.9 0.0022 18.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEP07432.1 - 0.031 14.0 1.0 0.052 13.3 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle PMSI1 PF15322.6 CEP07432.1 - 0.11 11.9 1.3 0.18 11.2 1.3 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative AAA_22 PF13401.6 CEP07432.1 - 0.38 11.0 3.1 29 4.9 0.3 3.5 3 1 0 3 3 3 0 AAA domain zf-CCHC_2 PF13696.6 CEP07432.1 - 0.93 9.4 5.5 0.45 10.4 2.3 2.0 2 0 0 2 2 2 0 Zinc knuckle UCH PF00443.29 CEP07434.1 - 1.2e-36 126.5 0.0 4.2e-36 124.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP07434.1 - 8.6e-10 38.7 0.5 5.4e-09 36.1 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase STAT_int PF02865.17 CEP07434.1 - 0.013 16.0 0.5 0.74 10.3 0.0 2.6 2 1 1 3 3 3 0 STAT protein, protein interaction domain Peptidase_C98 PF15499.6 CEP07434.1 - 0.38 10.2 2.1 31 3.9 0.0 3.2 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ANAPC4_WD40 PF12894.7 CEP07435.1 - 1.7e-06 28.3 0.0 0.023 15.0 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP07435.1 - 0.00022 21.9 0.3 0.026 15.4 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat CD45 PF12567.8 CEP07437.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Leukocyte receptor CD45 Prefoldin_2 PF01920.20 CEP07438.1 - 3.5e-25 88.0 5.9 3.9e-25 87.8 5.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit ATPase PF06745.13 CEP07438.1 - 0.0024 17.3 0.1 0.0031 16.9 0.1 1.3 1 1 0 1 1 1 1 KaiC BLOC1_2 PF10046.9 CEP07438.1 - 0.0071 16.6 3.7 0.16 12.3 0.4 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5595 PF18077.1 CEP07438.1 - 0.015 15.4 6.9 0.59 10.3 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) TPR_MLP1_2 PF07926.12 CEP07438.1 - 0.024 14.7 0.9 0.024 14.7 0.9 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2935 PF11155.8 CEP07438.1 - 0.025 14.9 0.5 0.032 14.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Prefoldin_3 PF13758.6 CEP07438.1 - 0.027 14.5 0.9 0.8 9.8 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 CEP07438.1 - 0.033 12.8 2.7 0.043 12.4 2.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 CEP07438.1 - 0.041 13.9 1.0 0.041 13.9 1.0 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.5 CEP07438.1 - 0.065 12.9 4.7 0.43 10.2 4.7 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DASH_Dad3 PF08656.10 CEP07438.1 - 0.069 13.3 2.8 0.053 13.6 1.0 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad3 IFT57 PF10498.9 CEP07438.1 - 0.079 11.9 7.0 1.5 7.7 0.4 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TMF_TATA_bd PF12325.8 CEP07438.1 - 0.084 13.1 6.7 2.2 8.5 6.8 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 CEP07438.1 - 0.085 12.2 7.5 0.81 9.0 0.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZnuA PF01297.17 CEP07438.1 - 0.089 12.2 1.0 0.13 11.6 0.2 1.6 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Prefoldin PF02996.17 CEP07438.1 - 0.15 12.0 4.8 11 6.0 4.6 2.1 1 1 0 1 1 1 0 Prefoldin subunit DivIC PF04977.15 CEP07438.1 - 0.15 11.8 4.6 0.44 10.4 2.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Rootletin PF15035.6 CEP07438.1 - 0.16 12.0 4.5 3.1 7.8 1.0 2.0 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DASH_Spc34 PF08657.10 CEP07438.1 - 0.36 10.6 7.1 0.25 11.1 2.1 1.9 1 1 0 2 2 2 0 DASH complex subunit Spc34 OmpH PF03938.14 CEP07438.1 - 0.52 10.6 9.0 3.6 7.9 9.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 CEP07438.1 - 0.6 10.2 5.2 0.23 11.6 1.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CEP07438.1 - 1.2 9.6 8.6 1.4 9.4 5.3 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Sod_Cu PF00080.20 CEP07439.1 - 9.4e-34 116.6 3.2 9.4e-34 116.6 1.9 1.7 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 CEP07439.1 - 2e-15 57.0 1.7 4.3e-15 55.9 0.0 2.3 3 0 0 3 3 3 1 Heavy-metal-associated domain Inhibitor_I9 PF05922.16 CEP07439.1 - 5.1e-06 27.1 0.2 9.1e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 SWIRM-assoc_3 PF16498.5 CEP07439.1 - 0.071 13.4 0.2 0.45 10.8 0.3 2.1 1 1 1 2 2 2 0 SWIRM-associated domain at the C-terminal DUF1939 PF09154.10 CEP07439.1 - 0.09 13.0 0.4 0.23 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) U1snRNP70_N PF12220.8 CEP07440.1 - 0.0062 17.2 6.4 0.0091 16.6 6.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Eapp_C PF10238.9 CEP07440.1 - 0.01 16.0 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 E2F-associated phosphoprotein NARP1 PF12569.8 CEP07440.1 - 0.022 13.7 4.1 0.025 13.5 4.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 CEP07440.1 - 0.026 14.6 6.3 0.037 14.1 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM176 PF14851.6 CEP07440.1 - 0.032 13.9 0.5 0.049 13.3 0.5 1.2 1 0 0 1 1 1 0 FAM176 family Peroxin-13_N PF04088.13 CEP07440.1 - 0.079 13.2 1.9 0.13 12.6 1.9 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Connexin PF00029.19 CEP07440.1 - 0.12 12.1 1.4 0.15 11.8 1.4 1.2 1 0 0 1 1 1 0 Connexin DUF4629 PF15442.6 CEP07440.1 - 0.13 12.4 16.3 0.098 12.9 14.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) Presenilin PF01080.17 CEP07440.1 - 0.14 10.9 0.3 0.14 10.9 0.3 1.2 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CEP07440.1 - 0.15 11.8 3.4 0.27 11.0 3.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AP3D1 PF06375.11 CEP07440.1 - 0.18 12.0 10.5 0.26 11.5 10.5 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MAS20 PF02064.15 CEP07440.1 - 0.84 9.7 6.1 1.5 9.0 6.1 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Coilin_N PF15862.5 CEP07440.1 - 4.5 7.1 12.9 10 5.9 12.9 1.6 1 0 0 1 1 1 0 Coilin N-terminus Phlebovirus_G1 PF07243.11 CEP07441.1 - 0.035 12.5 3.5 0.038 12.4 3.5 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Emaravirus_P4 PF16505.5 CEP07441.1 - 0.037 13.1 0.4 0.037 13.0 0.4 1.0 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily DNA_pol_phi PF04931.13 CEP07442.1 - 9.7e-212 705.2 24.0 9.7e-212 705.2 24.0 1.7 2 0 0 2 2 2 1 DNA polymerase phi DUF2277 PF10041.9 CEP07442.1 - 0.15 12.4 0.8 3.3 8.1 0.1 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) Sirohm_synth_C PF14823.6 CEP07442.1 - 0.16 11.6 0.2 0.67 9.6 0.2 2.2 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DUF4203 PF13886.6 CEP07444.1 - 6.7e-30 104.3 41.6 8.8e-30 103.9 41.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Tape_meas_lam_C PF09718.10 CEP07444.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.3 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ABC_tran PF00005.27 CEP07445.1 - 1.6e-36 125.8 0.1 1.2e-18 68.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CEP07445.1 - 8.4e-15 54.3 5.6 2.1e-14 53.0 5.6 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CEP07445.1 - 1e-12 48.0 3.5 9.3e-05 22.0 0.9 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEP07445.1 - 1.3e-10 41.5 12.0 0.0057 16.5 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CEP07445.1 - 2.9e-08 33.2 2.6 2.9e-08 33.2 2.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 CEP07445.1 - 5.1e-06 26.3 12.3 1.1e-05 25.3 2.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 CEP07445.1 - 6.4e-06 25.8 0.2 0.045 13.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP07445.1 - 2e-05 24.6 0.1 0.066 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 CEP07445.1 - 4.1e-05 23.6 0.0 0.028 14.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 CEP07445.1 - 0.00016 21.5 8.7 0.073 12.8 0.1 3.5 2 2 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 CEP07445.1 - 0.00056 20.3 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEP07445.1 - 0.00086 19.7 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.6 CEP07445.1 - 0.0011 19.1 12.4 0.0019 18.3 12.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.6 CEP07445.1 - 0.0013 19.3 2.9 0.066 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.17 CEP07445.1 - 0.0014 18.3 0.2 3.5 7.3 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase Fer4_2 PF12797.7 CEP07445.1 - 0.0025 17.8 0.9 0.0025 17.8 0.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 CEP07445.1 - 0.0036 17.6 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP07445.1 - 0.004 17.7 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CEP07445.1 - 0.0041 17.2 1.3 0.0041 17.2 1.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEP07445.1 - 0.0043 17.6 11.0 0.012 16.2 11.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CEP07445.1 - 0.0044 17.1 11.8 0.0084 16.2 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CEP07445.1 - 0.0081 16.5 0.1 4 7.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CEP07445.1 - 0.0081 15.9 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEP07445.1 - 0.012 15.6 2.2 0.58 10.2 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEP07445.1 - 0.014 15.5 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 CEP07445.1 - 0.015 16.2 8.4 0.017 16.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NACHT PF05729.12 CEP07445.1 - 0.017 15.1 1.6 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 CEP07445.1 - 0.019 14.2 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 CEP07445.1 - 0.023 14.3 2.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CEP07445.1 - 0.026 14.2 0.2 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CEP07445.1 - 0.035 14.3 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CEP07445.1 - 0.054 12.8 0.2 1.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.11 CEP07445.1 - 0.06 13.1 0.0 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_28 PF13521.6 CEP07445.1 - 0.064 13.5 0.6 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 CEP07445.1 - 0.07 13.7 1.0 0.07 13.7 1.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain MeaB PF03308.16 CEP07445.1 - 0.072 12.1 0.1 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 CEP07445.1 - 0.079 12.1 0.1 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CEP07445.1 - 0.083 13.0 2.3 4.2 7.5 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Synapsin PF02078.16 CEP07445.1 - 0.086 13.1 0.1 1 9.7 0.0 2.4 2 0 0 2 2 2 0 Synapsin, N-terminal domain Fer4_8 PF13183.6 CEP07445.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 CEP07445.1 - 0.32 10.9 1.2 18 5.2 0.0 3.4 3 0 0 3 3 3 0 NTPase Fer4_4 PF12800.7 CEP07445.1 - 0.7 10.5 15.9 0.2 12.3 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 CEP07445.1 - 7.8 7.7 17.0 0.13 13.3 4.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Sec20 PF03908.13 CEP07446.1 - 1.3e-17 63.5 1.8 1.3e-17 63.5 1.8 2.5 2 1 0 2 2 2 1 Sec20 BatA PF07584.11 CEP07446.1 - 0.0072 16.7 0.5 0.027 14.8 0.5 2.0 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal HOASN PF14515.6 CEP07446.1 - 0.027 14.9 0.2 0.071 13.5 0.2 1.7 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices CCDC-167 PF15188.6 CEP07446.1 - 0.18 12.2 9.0 0.072 13.4 5.3 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 PilJ PF13675.6 CEP07446.1 - 0.29 11.2 3.3 2.2 8.3 0.3 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Aminotran_1_2 PF00155.21 CEP07447.1 - 7.4e-77 259.0 0.0 9.3e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP07447.1 - 3.3e-06 25.9 0.0 6.1e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEP07447.1 - 0.00019 20.5 0.0 0.00082 18.4 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.10 CEP07447.1 - 0.0012 19.3 2.0 0.0026 18.2 2.0 1.5 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Beta_elim_lyase PF01212.21 CEP07447.1 - 0.0029 16.9 0.0 0.006 15.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3405 PF11885.8 CEP07447.1 - 0.02 13.5 0.1 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Pex24p PF06398.11 CEP07448.1 - 1.8e-20 73.3 13.2 3.1e-20 72.5 13.2 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 CEP07448.1 - 0.0032 16.9 0.1 0.0053 16.2 0.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF2502 PF10697.9 CEP07448.1 - 1.3 9.5 18.4 0.16 12.3 10.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2502) MatB PF16449.5 CEP07451.1 - 0.063 13.1 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin MatB p25-alpha PF05517.12 CEP07451.1 - 0.098 12.8 0.7 1.9 8.7 0.1 2.3 1 1 1 2 2 2 0 p25-alpha DHR10 PF18595.1 CEP07452.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Lzipper-MIP1 PF14389.6 CEP07452.1 - 0.055 13.8 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 CEP07452.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF5082 PF16888.5 CEP07452.1 - 0.14 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DAZAP2 PF11029.8 CEP07452.1 - 0.19 12.7 7.0 3.8 8.4 0.0 2.6 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) betaPIX_CC PF16523.5 CEP07452.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil DHHC PF01529.20 CEP07453.1 - 0.013 15.6 10.0 0.024 14.7 10.0 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Choline_kinase PF01633.20 CEP07454.1 - 5.1e-65 219.0 0.0 6.9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CEP07454.1 - 9.5e-13 48.6 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family UvrD_C PF13361.6 CEP07455.1 - 5.1e-34 118.2 7.6 5.2e-23 82.0 0.1 3.4 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CEP07455.1 - 6.8e-30 104.7 3.9 6.8e-30 104.7 3.9 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CEP07455.1 - 6.7e-10 39.5 0.1 1.7e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CEP07455.1 - 6.7e-09 35.4 0.0 2.2e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 CEP07455.1 - 0.042 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CEP07456.1 - 9.7e-55 185.8 0.0 2.6e-54 184.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain CRAL_TRIO PF00650.20 CEP07456.1 - 7.2e-42 142.8 1.0 2.4e-41 141.1 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO domain Pkinase_Tyr PF07714.17 CEP07456.1 - 4.5e-27 95.0 0.0 8e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CRAL_TRIO_2 PF13716.6 CEP07456.1 - 1.8e-08 34.6 0.1 2.6e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP07456.1 - 2.9e-07 30.6 0.0 7.1e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RIO1 PF01163.22 CEP07456.1 - 0.019 14.6 0.8 0.043 13.4 0.8 1.5 1 0 0 1 1 1 0 RIO1 family DUF1326 PF07040.11 CEP07456.1 - 0.28 11.2 0.6 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) Pkinase_fungal PF17667.1 CEP07456.1 - 0.44 9.3 3.8 0.18 10.5 0.1 2.1 2 1 0 2 2 2 0 Fungal protein kinase Polysacc_deac_1 PF01522.21 CEP07457.1 - 1.3e-28 99.4 0.0 2.1e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase C1ORF64 PF15547.6 CEP07458.1 - 0.57 10.6 4.5 0.23 11.9 0.9 2.1 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein TGT PF01702.18 CEP07459.1 - 1.2e-77 261.4 0.0 1.5e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Amidohydro_2 PF04909.14 CEP07460.1 - 5.7e-08 32.9 0.0 1.1e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CEP07460.1 - 6.3e-05 22.5 0.1 0.00015 21.2 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP07460.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family HEAT PF02985.22 CEP07461.1 - 0.0046 17.1 0.2 54 4.4 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat SCAMP PF04144.13 CEP07461.1 - 0.14 12.5 0.1 0.38 11.0 0.1 1.7 2 0 0 2 2 2 0 SCAMP family WD40 PF00400.32 CEP07462.1 - 7e-57 188.1 19.8 1.3e-06 29.0 0.2 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07462.1 - 1.4e-21 76.6 4.1 0.008 16.5 0.0 8.3 5 2 4 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CEP07462.1 - 1.8e-18 66.8 0.2 3.4e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CEP07462.1 - 9.4e-08 31.4 5.4 0.0072 15.3 0.0 5.9 3 2 4 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEP07462.1 - 1.7e-07 30.9 0.0 0.67 9.2 0.1 4.8 5 0 0 5 5 5 3 WD40-like domain Nup160 PF11715.8 CEP07462.1 - 0.0017 17.1 9.0 2.7 6.5 0.0 5.7 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Utp13 PF08625.11 CEP07462.1 - 0.65 9.9 2.6 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain CHCH PF06747.13 CEP07463.1 - 5e-06 26.5 11.0 8.8e-06 25.7 11.0 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CEP07463.1 - 0.0036 17.5 5.2 0.0055 16.9 5.2 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 CEP07463.1 - 0.013 15.8 7.1 0.019 15.2 7.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TAP_C PF03943.13 CEP07463.1 - 0.069 12.8 0.6 0.1 12.3 0.6 1.3 1 0 0 1 1 1 0 TAP C-terminal domain Ribosomal_60s PF00428.19 CEP07464.1 - 2.6e-25 88.8 5.4 3.7e-25 88.3 5.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FAM91_C PF14648.6 CEP07464.1 - 0.014 14.2 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus EVI2A PF05399.11 CEP07465.1 - 5.9e-05 22.8 7.3 9.8e-05 22.1 7.3 1.2 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.6 CEP07465.1 - 0.0019 18.1 0.2 0.0019 18.1 0.2 2.2 1 1 1 2 2 1 1 TMEM154 protein family DUF2207 PF09972.9 CEP07465.1 - 0.018 13.9 0.6 0.024 13.4 0.4 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 CEP07465.1 - 0.025 14.7 0.3 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase STIMATE PF12400.8 CEP07465.1 - 0.041 14.4 0.8 0.079 13.5 0.1 1.7 2 0 0 2 2 2 0 STIMATE family Apt1 PF10351.9 CEP07465.1 - 0.042 12.7 1.3 0.049 12.5 1.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BPD_transp_2 PF02653.16 CEP07465.1 - 0.044 12.9 0.3 0.065 12.4 0.3 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF4834 PF16118.5 CEP07465.1 - 0.062 14.3 0.0 0.062 14.3 0.0 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) DUF5305 PF17231.2 CEP07465.1 - 0.072 12.5 6.8 7.2 6.0 7.0 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5305) DUF1201 PF06716.11 CEP07465.1 - 0.078 13.0 0.5 0.078 13.0 0.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1201) Macoilin PF09726.9 CEP07465.1 - 0.2 10.2 1.4 0.23 10.0 1.4 1.1 1 0 0 1 1 1 0 Macoilin family HemY_N PF07219.13 CEP07465.1 - 0.25 11.5 1.3 0.44 10.8 0.2 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Orf78 PF06024.12 CEP07465.1 - 0.27 11.6 1.2 0.97 9.8 0.0 2.1 1 1 0 2 2 2 0 Orf78 (ac78) ADP_PFK_GK PF04587.15 CEP07465.1 - 0.31 9.6 2.3 0.43 9.1 2.3 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region CcmD PF04995.14 CEP07465.1 - 0.44 10.7 1.7 0.48 10.5 0.1 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) OAD_gamma PF04277.13 CEP07465.1 - 0.48 11.0 3.6 5.2 7.7 0.2 2.6 2 2 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CCDC142 PF14923.6 CEP07465.1 - 0.94 8.1 7.4 1.2 7.8 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 SPX PF03105.19 CEP07465.1 - 5.1 6.9 9.3 8.7 6.1 9.3 1.3 1 0 0 1 1 1 0 SPX domain NDUF_C2 PF06374.11 CEP07466.1 - 0.043 14.0 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) GTP1_OBG PF01018.22 CEP07467.1 - 1.3e-46 158.1 8.1 1.5e-30 105.8 5.1 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CEP07467.1 - 4.1e-24 84.9 0.0 8.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP07467.1 - 7.6e-10 38.5 0.0 2e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CEP07467.1 - 6.5e-08 32.2 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP07467.1 - 8.6e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_C PF08438.10 CEP07467.1 - 0.00081 20.0 0.4 0.0018 18.8 0.4 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal Dynamin_N PF00350.23 CEP07467.1 - 0.0095 16.0 0.1 2.6 8.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 CEP07467.1 - 0.016 14.2 0.2 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CEP07467.1 - 0.023 15.2 0.0 0.072 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CEP07467.1 - 0.025 14.5 0.2 0.99 9.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CEP07467.1 - 0.047 13.2 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 CEP07467.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L10 PF00466.20 CEP07468.1 - 5.7e-24 84.2 0.3 1.2e-23 83.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CEP07468.1 - 5.6e-22 77.5 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CEP07468.1 - 9.3e-20 71.0 5.3 1.1e-19 70.8 3.4 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein FAM184 PF15665.5 CEP07469.1 - 0.00031 20.6 41.8 0.00031 20.6 41.8 10.4 1 1 9 10 10 10 4 Family with sequence similarity 184, A and B Fungal_trans PF04082.18 CEP07470.1 - 7.5e-30 103.9 0.6 1.7e-29 102.7 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPRY PF00622.28 CEP07471.1 - 1.4e-20 73.6 0.5 2.9e-20 72.6 0.2 1.7 2 0 0 2 2 2 1 SPRY domain Endosulfine PF04667.17 CEP07472.1 - 2.5e-27 94.8 0.4 3.3e-27 94.4 0.3 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region bZIP_2 PF07716.15 CEP07474.1 - 3.9e-11 42.9 6.5 3.9e-11 42.9 6.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP07474.1 - 1.8e-07 31.1 8.4 1.8e-07 31.1 8.4 2.3 1 1 2 3 3 3 2 bZIP transcription factor bZIP_Maf PF03131.17 CEP07474.1 - 2e-05 25.0 3.5 2e-05 25.0 3.5 1.7 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 CEP07474.1 - 0.005 16.2 6.5 0.0073 15.6 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HAP1_N PF04849.13 CEP07474.1 - 0.021 14.0 8.1 0.067 12.4 8.1 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region M PF02370.16 CEP07474.1 - 0.071 13.7 4.3 1.3 9.9 0.5 3.6 2 1 1 3 3 3 0 M protein repeat ASD2 PF08687.11 CEP07474.1 - 0.086 12.4 0.2 0.086 12.4 0.2 2.2 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Nup54 PF13874.6 CEP07474.1 - 0.13 12.4 8.4 0.22 11.6 8.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 CEP07474.1 - 0.15 11.4 4.7 0.22 10.8 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 CEP07474.1 - 0.43 10.3 6.5 2.6 7.8 4.2 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HalX PF08663.10 CEP07474.1 - 0.47 10.8 8.6 4.4 7.7 8.6 2.4 1 1 1 2 2 2 0 HalX domain ABC_tran_CTD PF16326.5 CEP07474.1 - 0.53 10.6 5.7 9.4 6.6 0.4 2.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 CEP07474.1 - 3.6 7.4 11.3 0.065 13.0 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 CEP07474.1 - 5.5 4.8 6.3 6.5 4.5 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_25 PF13649.6 CEP07475.1 - 4.1e-17 62.7 0.0 9.6e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP07475.1 - 2.7e-15 56.6 0.0 4.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP07475.1 - 2.4e-14 53.7 0.0 6.8e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP07475.1 - 3.6e-12 46.3 0.0 3.8e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP07475.1 - 1e-09 39.0 0.0 2.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP07475.1 - 3.6e-06 26.6 0.0 2.4e-05 23.9 0.0 2.3 2 1 1 3 3 3 1 Putative methyltransferase CheR PF01739.18 CEP07475.1 - 1.8e-05 24.3 0.0 0.00028 20.4 0.0 2.3 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 CEP07475.1 - 8e-05 22.1 0.0 0.00069 19.0 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CEP07475.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 CEP07475.1 - 0.0015 17.2 0.0 0.014 14.0 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 CEP07475.1 - 0.002 18.0 0.0 0.018 14.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.14 CEP07475.1 - 0.0034 16.8 0.0 0.0092 15.4 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 CEP07475.1 - 0.0091 15.6 0.0 0.032 13.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Pox_MCEL PF03291.16 CEP07475.1 - 0.014 14.6 0.6 0.69 9.0 0.0 2.7 3 0 0 3 3 3 0 mRNA capping enzyme MetW PF07021.12 CEP07475.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 CEP07475.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 CEP07475.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CEP07475.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) IF3_C PF00707.22 CEP07477.1 - 6.1e-14 51.8 0.6 1.2e-13 50.8 0.6 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 CEP07477.1 - 2.8e-11 43.5 0.1 5.8e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 CEP07477.1 - 0.0028 17.3 5.4 0.0052 16.5 4.8 1.7 2 0 0 2 2 2 1 Mitochondrial translation initiation factor SPC25 PF06703.11 CEP07477.1 - 0.026 14.3 1.2 4.8 6.9 1.1 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Aminotran_1_2 PF00155.21 CEP07479.1 - 1e-63 215.7 0.0 1.2e-63 215.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP07479.1 - 0.00012 20.7 0.1 0.00056 18.6 0.1 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEP07479.1 - 0.00047 19.6 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEP07479.1 - 0.0013 17.8 0.0 0.031 13.3 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEP07479.1 - 0.002 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase LSM14 PF12701.7 CEP07481.1 - 1.6e-33 114.6 0.9 2.3e-31 107.7 0.1 2.4 2 0 0 2 2 2 2 Scd6-like Sm domain FDF PF09532.10 CEP07481.1 - 4.8e-12 46.7 15.4 4.8e-12 46.7 15.4 4.7 3 2 1 4 4 4 1 FDF domain SM-ATX PF14438.6 CEP07481.1 - 1.1e-07 31.9 0.0 3.3e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.25 CEP07484.1 - 1.6e-67 227.7 0.0 2.7e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07484.1 - 1e-35 123.3 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEP07484.1 - 7e-10 38.5 0.1 2.1e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 CEP07484.1 - 1.7e-08 34.2 0.0 4.3e-08 32.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CEP07484.1 - 0.00056 19.3 1.0 0.001 18.5 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEP07484.1 - 0.00074 19.2 0.4 0.0017 18.0 0.4 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CEP07484.1 - 0.036 14.0 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RXT2_N PF08595.11 CEP07485.1 - 0.37 10.8 9.1 3.8 7.5 3.0 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF4611 PF15387.6 CEP07485.1 - 0.44 10.8 5.8 0.3 11.3 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TipE PF16972.5 CEP07485.1 - 1.4 8.0 6.4 2.8 7.0 6.4 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE PBP1_TM PF14812.6 CEP07485.1 - 8.7 6.8 9.1 8.3 6.9 7.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_25 PF13481.6 CEP07487.1 - 0.047 13.3 0.2 2.2 7.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain EptA_B_N PF08019.12 CEP07487.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB NUDE_C PF04880.13 CEP07488.1 - 6.7e-15 56.0 18.3 6.7e-15 56.0 18.3 2.7 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region TPR_MLP1_2 PF07926.12 CEP07488.1 - 0.00018 21.6 38.8 0.0018 18.3 5.4 3.3 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 CEP07488.1 - 0.00048 17.8 24.2 0.00056 17.6 24.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.21 CEP07488.1 - 0.0049 16.5 6.1 0.0049 16.5 6.1 3.2 1 1 2 3 3 3 1 Intermediate filament protein PSII_Pbs27 PF13326.6 CEP07488.1 - 0.0082 16.5 1.5 0.0082 16.5 1.5 2.1 2 1 0 2 2 2 1 Photosystem II Pbs27 DUF1664 PF07889.12 CEP07488.1 - 0.19 11.8 19.3 0.067 13.2 3.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CEP07488.1 - 0.21 11.8 23.4 0.05 13.8 13.4 2.6 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 CEP07488.1 - 0.28 10.5 38.5 1.3 8.4 9.8 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 CEP07488.1 - 0.29 10.0 32.7 0.3 9.9 31.4 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BRE1 PF08647.11 CEP07488.1 - 0.35 11.0 31.2 2 8.5 18.4 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Allexi_40kDa PF05549.11 CEP07488.1 - 0.4 10.1 16.9 0.84 9.1 2.3 2.8 1 1 1 3 3 3 0 Allexivirus 40kDa protein HOOK PF05622.12 CEP07488.1 - 0.44 8.6 38.2 2.6 6.1 16.7 2.4 1 1 1 2 2 2 0 HOOK protein DUF2353 PF09789.9 CEP07488.1 - 1.1 8.6 34.1 2.8 7.2 7.1 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) PRKG1_interact PF15898.5 CEP07488.1 - 1.3 10.0 36.0 0.5 11.3 12.5 3.8 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Noelin-1 PF12308.8 CEP07488.1 - 1.4 8.9 15.5 0.13 12.3 6.3 3.1 2 1 0 3 3 3 0 Neurogenesis glycoprotein YfhO PF09586.10 CEP07488.1 - 1.8 6.7 6.9 2.1 6.5 6.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Fez1 PF06818.15 CEP07488.1 - 3.3 8.1 33.6 5.3 7.4 11.2 2.4 1 1 1 2 2 2 0 Fez1 DUF3450 PF11932.8 CEP07488.1 - 3.5 6.9 34.8 0.069 12.4 11.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) SKA1 PF07160.12 CEP07488.1 - 6.5 6.5 23.5 2.5 7.9 6.2 2.3 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Golgin_A5 PF09787.9 CEP07488.1 - 7.4 5.9 37.6 6.2 6.2 11.3 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF730 PF05325.11 CEP07488.1 - 7.5 6.6 11.3 0.2 11.7 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF730) DUF4407 PF14362.6 CEP07488.1 - 8.4 5.6 24.0 2.3 7.5 14.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CENP-Q PF13094.6 CEP07488.1 - 8.7 6.5 32.6 42 4.3 9.9 3.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AMP-binding PF00501.28 CEP07489.1 - 9.8e-78 261.6 0.0 1.2e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP07489.1 - 5.7e-21 75.3 0.0 1e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEP07489.1 - 7.7e-11 41.7 0.3 2e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Iso_dh PF00180.20 CEP07490.1 - 7.8e-81 271.9 0.4 9.1e-81 271.7 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SLC35F PF06027.12 CEP07492.1 - 6.7e-94 314.8 23.5 7.8e-94 314.5 23.5 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CEP07492.1 - 3.6e-09 36.0 5.6 3.6e-09 36.0 5.6 1.8 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CEP07492.1 - 4.1e-07 30.2 32.1 0.001 19.3 11.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEP07492.1 - 0.00051 19.3 19.7 0.00077 18.7 19.7 1.3 1 0 0 1 1 1 1 UAA transporter family TBP PF00352.21 CEP07493.1 - 3e-68 225.8 0.1 1.7e-33 114.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CEP07493.1 - 2.8e-05 24.2 0.0 0.2 11.8 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CEP07493.1 - 0.054 13.3 0.1 0.23 11.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) FAD-oxidase_C PF02913.19 CEP07494.1 - 7e-55 186.4 0.0 9.5e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEP07494.1 - 1.4e-31 109.1 0.0 2.1e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PX PF00787.24 CEP07495.1 - 7.7e-19 67.8 0.3 1.8e-18 66.6 0.3 1.6 1 0 0 1 1 1 1 PX domain SNARE PF05739.19 CEP07495.1 - 0.13 12.3 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 SNARE domain DUF2839 PF10999.8 CEP07495.1 - 0.18 12.2 0.1 0.49 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) DUF5320 PF17253.2 CEP07495.1 - 3.4 8.8 5.0 6.2 8.0 0.7 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Polysacc_deac_1 PF01522.21 CEP07496.1 - 7.5e-24 84.0 0.1 1.5e-23 83.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP07496.1 - 8.9e-05 21.8 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 RNA_pol_Rpb2_6 PF00562.28 CEP07497.1 - 8.7e-113 377.3 1.1 1.7e-112 376.3 1.1 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEP07497.1 - 1.1e-32 113.2 0.0 1.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CEP07497.1 - 2.5e-27 94.8 0.0 6.3e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CEP07497.1 - 6.8e-23 80.4 0.0 1.3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CEP07497.1 - 8.6e-23 80.6 0.0 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CEP07497.1 - 1.9e-22 79.8 0.0 3.4e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 zf-CCHC_2 PF13696.6 CEP07497.1 - 0.89 9.4 3.5 5.4 6.9 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Sugar_tr PF00083.24 CEP07499.1 - 5.5e-119 398.0 25.1 2.3e-89 300.3 15.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP07499.1 - 3.2e-36 125.0 18.1 3.2e-36 125.0 18.1 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEP07499.1 - 1.1e-06 27.5 9.1 1.4e-06 27.0 2.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CEP07499.1 - 5.4e-05 21.9 2.8 5.4e-05 21.9 2.8 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.13 CEP07499.1 - 0.00065 18.2 15.3 0.00086 17.8 4.3 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector PSI PF01437.25 CEP07499.1 - 0.0025 18.3 3.7 0.0041 17.6 3.7 1.3 1 0 0 1 1 1 1 Plexin repeat MFS_1_like PF12832.7 CEP07499.1 - 0.17 10.7 18.2 0.096 11.5 2.5 3.0 2 1 1 3 3 3 0 MFS_1 like family Phage_holin_3_2 PF04550.12 CEP07499.1 - 1.7 9.2 8.3 4.9 7.8 2.9 2.9 2 0 0 2 2 2 0 Phage holin family 2 Gp_dh_C PF02800.20 CEP07500.1 - 5e-71 237.4 0.0 7.1e-71 236.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEP07500.1 - 3.3e-39 133.3 0.0 9.7e-39 131.8 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CEP07500.1 - 0.062 13.4 0.1 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DnaJ_C PF01556.18 CEP07501.1 - 1.4e-37 129.1 0.1 1.9e-37 128.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP07501.1 - 2.7e-26 91.4 4.0 2.7e-26 91.4 4.0 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP07501.1 - 1.5e-10 41.3 19.0 2.8e-10 40.4 19.0 1.5 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 CEP07501.1 - 0.55 9.9 8.7 4.6 6.9 1.6 2.4 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 Anti-TRAP PF15777.5 CEP07501.1 - 0.59 10.1 14.4 1.5 8.8 4.4 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEP07501.1 - 1.8 8.6 12.0 2.4 8.2 2.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BRO1 PF03097.18 CEP07503.1 - 3.6e-126 421.1 2.5 3.6e-126 421.1 2.5 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEP07503.1 - 2.2e-54 184.8 15.1 2.2e-54 184.8 15.1 2.2 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CLZ PF16526.5 CEP07503.1 - 0.41 11.0 7.8 14 6.1 0.1 4.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RSS_P20 PF11757.8 CEP07503.1 - 4 7.9 9.1 3.8 8.0 0.1 4.2 4 1 0 4 4 4 0 Suppressor of RNA silencing P21-like N-terminal domain Peptidase_C48 PF02902.19 CEP07504.1 - 5.3e-16 59.1 1.4 9.3e-16 58.3 1.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Imm32 PF15566.6 CEP07504.1 - 0.063 13.1 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Immunity protein 32 PTN13_u3 PF16599.5 CEP07504.1 - 0.27 11.3 6.5 0.76 9.8 6.1 2.0 2 1 0 2 2 2 0 Unstructured linker region on PTN13 protein between PDZ zf-C2H2 PF00096.26 CEP07506.1 - 1.1e-10 41.3 20.7 0.00035 20.9 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP07506.1 - 9e-10 38.6 17.4 0.001 19.7 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP07506.1 - 4.1e-06 27.0 17.5 4.4e-05 23.7 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEP07506.1 - 1.1e-05 25.3 0.4 1.1e-05 25.3 0.4 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP07506.1 - 0.00013 22.1 13.6 0.17 12.2 2.5 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CEP07506.1 - 0.0072 17.0 11.8 0.21 12.3 0.8 3.5 1 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 CEP07506.1 - 0.015 15.4 2.0 0.83 9.8 0.3 2.7 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 CEP07506.1 - 0.27 11.6 4.2 0.66 10.3 4.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon s48_45 PF07422.13 CEP07506.1 - 1.1 9.9 10.5 2.8 8.5 0.1 3.3 2 1 1 3 3 3 0 Sexual stage antigen s48/45 domain zf-LYAR PF08790.11 CEP07506.1 - 8.4 6.4 9.2 8.3 6.4 0.0 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger RPA43_OB PF17875.1 CEP07507.1 - 1.2e-25 90.5 0.8 5.2e-25 88.5 0.1 1.9 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CEP07507.1 - 6.2e-11 42.5 0.0 1.8e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Inhibitor_I34 PF10466.9 CEP07507.1 - 0.072 13.7 4.7 2.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 eIF3g PF12353.8 CEP07507.1 - 0.11 12.9 0.0 0.11 12.9 0.0 2.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G XkdW PF09636.10 CEP07509.1 - 0.0055 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 XkdW protein DDE_3 PF13358.6 CEP07510.1 - 1.2e-24 86.7 0.1 6.7e-18 64.8 0.1 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP07510.1 - 0.00039 20.1 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain DUF1804 PF08822.11 CEP07510.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_32 PF13565.6 CEP07510.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEP07510.1 - 0.095 12.8 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 CEP07510.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Polysacc_deac_1 PF01522.21 CEP07511.1 - 6.2e-08 32.6 0.0 1.6e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase HTH_psq PF05225.16 CEP07512.1 - 6.1e-08 32.3 0.0 2.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP07512.1 - 9e-05 22.5 0.3 0.00023 21.2 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CEP07512.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CEP07512.1 - 0.0021 17.8 0.1 0.0053 16.5 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain UPF0175 PF03683.13 CEP07512.1 - 0.024 14.3 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_3 PF01381.22 CEP07512.1 - 0.032 14.3 0.1 0.14 12.2 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 CEP07512.1 - 0.046 13.3 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 FeoC PF09012.10 CEP07512.1 - 0.08 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator RPA_C PF08784.11 CEP07512.1 - 0.16 12.6 0.0 0.58 10.8 0.0 1.8 2 0 0 2 2 2 0 Replication protein A C terminal HTH_Tnp_ISL3 PF13542.6 CEP07512.1 - 0.18 11.2 0.5 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PMM PF03332.13 CEP07514.1 - 8.6e-109 362.5 1.2 9.8e-109 362.3 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CEP07514.1 - 3.7e-06 26.9 0.1 3.1e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CEP07514.1 - 0.005 16.4 0.0 2.2 7.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase DUF600 PF04634.12 CEP07514.1 - 0.064 13.3 0.0 0.25 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF600 HAD PF12710.7 CEP07514.1 - 0.24 11.8 0.9 2.3 8.6 0.3 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Motile_Sperm PF00635.26 CEP07515.1 - 4.9e-07 29.6 0.0 3.1e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 MSP (Major sperm protein) domain eIF2A PF08662.11 CEP07516.1 - 1e-83 280.0 2.2 8.6e-80 267.2 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CEP07516.1 - 0.13 10.7 0.0 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain SURF4 PF02077.15 CEP07517.1 - 5.4e-59 200.0 4.9 3.6e-33 115.3 1.1 2.0 1 1 1 2 2 2 2 SURF4 family DUF624 PF04854.14 CEP07517.1 - 2 8.6 8.7 0.16 12.1 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Semialdhyde_dhC PF02774.18 CEP07518.1 - 5.6e-40 137.4 0.1 7.6e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CEP07518.1 - 5.5e-31 107.5 0.0 9.1e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 CEP07518.1 - 0.016 14.8 0.2 0.038 13.6 0.1 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 CEP07518.1 - 0.03 15.0 0.1 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ldh_1_N PF00056.23 CEP07518.1 - 0.033 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CEP07518.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Cyclin_N PF00134.23 CEP07519.1 - 1.8e-13 50.4 0.3 3.5e-13 49.4 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DcrB PF08786.11 CEP07519.1 - 0.08 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 DcrB Asp PF00026.23 CEP07520.1 - 4.9e-65 220.0 1.4 8.2e-65 219.3 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_S24e PF01282.19 CEP07520.1 - 3.3e-36 123.1 0.1 1.1e-35 121.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S24e TAXi_N PF14543.6 CEP07520.1 - 8.1e-17 62.0 0.0 9.7e-08 32.4 0.0 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CEP07520.1 - 0.00099 19.6 0.0 1.8 9.2 0.0 3.6 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CEP07520.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP07520.1 - 0.0011 19.6 0.0 5 7.8 0.0 3.4 2 2 0 2 2 2 2 Aspartyl protease Sld5 PF05916.11 CEP07521.1 - 5.1e-09 36.6 0.0 7.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Acetyltransf_1 PF00583.25 CEP07522.1 - 1.5e-06 28.4 0.0 4.6e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family EMC3_TMCO1 PF01956.16 CEP07522.1 - 0.02 14.6 0.5 0.068 12.9 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Acetyltransf_10 PF13673.7 CEP07522.1 - 0.03 14.2 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP07522.1 - 0.038 14.4 0.0 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain RhoGEF PF00621.20 CEP07523.1 - 5.7e-26 91.9 3.2 5.7e-26 91.9 3.2 1.7 2 0 0 2 2 2 1 RhoGEF domain MFS_1 PF07690.16 CEP07525.1 - 3.2e-38 131.6 59.6 1.7e-28 99.6 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07525.1 - 4.7e-06 25.7 37.7 1.9e-05 23.7 17.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter UPF0240 PF06784.11 CEP07526.1 - 0.00064 19.8 0.5 0.00064 19.8 0.5 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0240) Fe_hyd_SSU PF02256.17 CEP07526.1 - 0.27 11.4 1.6 0.83 9.8 1.4 1.9 2 0 0 2 2 2 0 Iron hydrogenase small subunit DUF4696 PF15767.5 CEP07527.1 - 0.0012 17.5 0.0 0.0015 17.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4696) zf-CCCH PF00642.24 CEP07528.1 - 2.4e-08 33.7 2.1 6.9e-08 32.2 2.1 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP07528.1 - 0.00013 21.9 3.5 0.00044 20.2 3.5 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEP07528.1 - 0.00062 19.5 1.8 0.00062 19.5 1.8 2.5 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 CEP07528.1 - 0.39 11.4 4.3 0.14 12.8 1.4 1.8 1 1 0 1 1 1 0 Torus domain ABC_tran PF00005.27 CEP07529.1 - 1e-36 126.5 0.1 2.1e-35 122.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 CEP07529.1 - 3.8e-34 118.6 10.3 8.3e-34 117.5 10.3 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region MTABC_N PF16185.5 CEP07529.1 - 3.9e-09 36.4 2.3 2e-08 34.0 2.3 2.1 1 1 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 CEP07529.1 - 1.2e-06 28.2 5.6 4.5e-06 26.3 0.0 3.0 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEP07529.1 - 0.0057 17.0 0.1 0.019 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP07529.1 - 0.0089 16.3 0.1 0.074 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEP07529.1 - 0.01 15.8 0.3 0.041 13.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CEP07529.1 - 0.014 15.1 0.1 0.043 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CEP07529.1 - 0.023 14.5 0.1 0.13 12.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 CEP07529.1 - 0.031 14.3 0.1 0.42 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 CEP07529.1 - 0.067 13.6 0.0 0.56 10.6 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thaumatin PF00314.17 CEP07530.1 - 4.7e-46 157.1 15.4 2.9e-45 154.5 15.4 1.9 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CEP07530.1 - 3.7e-06 26.5 2.8 0.27 10.5 0.0 3.1 3 0 0 3 3 3 3 Beta-1,3-glucanase Zn_clus PF00172.18 CEP07531.1 - 0.00021 21.3 5.1 0.00043 20.3 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF883 PF05957.13 CEP07531.1 - 0.059 14.0 1.6 5.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EAP30 PF04157.16 CEP07531.1 - 1.9 7.7 4.0 10 5.3 0.3 2.6 3 0 0 3 3 3 0 EAP30/Vps36 family F-box PF00646.33 CEP07532.1 - 0.00058 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CEP07532.1 - 0.011 15.7 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 0 F-box Ferritin-like PF12902.7 CEP07533.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like HTH_32 PF13565.6 CEP07534.1 - 0.015 15.9 0.0 0.054 14.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF2605 PF10792.9 CEP07534.1 - 0.048 13.6 0.6 2.6 8.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) PH PF00169.29 CEP07535.1 - 1.1e-08 35.5 0.4 3.4e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 PH domain PAGK PF15284.6 CEP07536.1 - 0.047 13.6 0.6 0.12 12.3 0.1 1.8 1 1 1 2 2 2 0 Phage-encoded virulence factor zf-RVT PF13966.6 CEP07537.1 - 0.00033 21.3 0.7 0.00067 20.3 0.7 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase G-alpha PF00503.20 CEP07538.1 - 3.4e-62 210.6 4.9 3.9e-62 210.5 4.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP07538.1 - 1.1e-09 38.0 0.5 4.9e-09 35.9 0.1 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family Nucleotid_trans PF03407.16 CEP07539.1 - 4.8e-25 88.8 0.2 6.9e-25 88.3 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HA70_C PF17993.1 CEP07539.1 - 0.04 14.0 0.1 0.27 11.3 0.0 2.2 2 1 1 3 3 3 0 Haemagglutinin 70 C-terminal domain Chs7 PF12271.8 CEP07540.1 - 2e-114 381.8 21.6 2.9e-114 381.3 21.6 1.2 1 0 0 1 1 1 1 Chitin synthase export chaperone TIM21 PF08294.11 CEP07540.1 - 1.6e-41 141.6 0.2 1.6e-41 141.6 0.2 2.0 2 0 0 2 2 2 1 TIM21 ArfGap PF01412.18 CEP07540.1 - 1.1e-28 99.7 0.1 1.1e-28 99.7 0.1 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Coa1 PF08695.10 CEP07540.1 - 6.8e-09 35.5 0.1 7.7e-08 32.1 0.1 2.7 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Septin PF00735.18 CEP07541.1 - 9.8e-122 405.6 0.3 9.8e-122 405.6 0.3 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEP07541.1 - 4.9e-09 36.3 1.1 9.7e-09 35.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP07541.1 - 7.2e-08 32.5 0.2 1.1e-05 25.4 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEP07541.1 - 1.5e-05 24.6 2.7 0.00085 18.9 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CEP07541.1 - 0.00017 21.9 0.0 0.0015 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEP07541.1 - 0.00017 22.1 2.9 0.0019 18.7 0.1 2.5 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 CEP07541.1 - 0.00052 19.4 0.0 0.00052 19.4 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 CEP07541.1 - 0.0009 19.5 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP07541.1 - 0.0011 18.6 0.9 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 CEP07541.1 - 0.0012 19.3 0.1 0.0044 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 CEP07541.1 - 0.0042 16.5 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CEP07541.1 - 0.005 16.9 0.1 0.005 16.9 0.1 3.1 2 2 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 CEP07541.1 - 0.023 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CEP07541.1 - 0.039 13.7 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP07541.1 - 0.08 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CEP07541.1 - 0.25 11.8 7.6 26 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEP07541.1 - 0.37 10.8 3.2 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 CEP07541.1 - 0.41 10.2 5.8 0.68 9.4 5.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4776 PF16003.5 CEP07541.1 - 0.58 9.1 9.8 0.85 8.5 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Atg14 PF10186.9 CEP07541.1 - 0.77 8.8 7.3 1.2 8.2 7.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_bind_1 PF03029.17 CEP07541.1 - 1.5 8.5 5.1 18 5.0 0.0 3.4 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DSS1_SEM1 PF05160.13 CEP07542.1 - 0.027 14.5 4.7 0.063 13.3 4.7 1.6 1 0 0 1 1 1 0 DSS1/SEM1 family DUF1664 PF07889.12 CEP07542.1 - 0.041 13.9 2.7 0.087 12.9 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PseudoU_synth_1 PF01416.20 CEP07543.1 - 3.9e-28 98.1 0.0 1.3e-25 90.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Herpes_LMP1 PF05297.11 CEP07544.1 - 0.055 12.7 4.0 0.058 12.6 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Zip PF02535.22 CEP07544.1 - 0.13 11.4 4.4 0.14 11.3 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 CEP07544.1 - 0.36 10.2 19.6 0.45 9.9 19.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 CEP07544.1 - 0.66 8.9 23.1 0.75 8.7 23.1 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 CEP07544.1 - 0.74 7.9 19.7 0.82 7.8 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CEP07544.1 - 0.78 9.1 19.3 0.81 9.1 19.3 1.2 1 0 0 1 1 1 0 SDA1 Neur_chan_memb PF02932.16 CEP07544.1 - 1.2 9.1 3.2 1.3 9.1 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CEP07544.1 - 1.6 8.4 15.0 1.9 8.3 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RXT2_N PF08595.11 CEP07544.1 - 5 7.1 24.2 70 3.4 24.2 2.0 1 1 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 CEP07544.1 - 6.1 5.9 13.7 6.5 5.8 13.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM60A PF15396.6 CEP07544.1 - 9.1 6.2 8.9 13 5.7 8.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BUD22 PF09073.10 CEP07546.1 - 0.00015 21.3 25.8 0.00018 21.0 25.8 1.0 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 CEP07546.1 - 0.0073 14.7 23.7 0.012 13.9 23.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Hid1 PF12722.7 CEP07546.1 - 0.63 8.1 9.9 0.75 7.9 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 CEP07546.1 - 1.6 6.9 36.8 2 6.5 36.8 1.1 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.12 CEP07546.1 - 2.5 8.3 4.6 3.1 8.0 4.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family IFT57 PF10498.9 CEP07546.1 - 6.6 5.6 18.0 9.4 5.1 18.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SAPS PF04499.15 CEP07546.1 - 7.6 5.2 12.7 8.3 5.1 12.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DrrA_P4M PF14860.6 CEP07547.1 - 0.018 14.9 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain ABC2_membrane PF01061.24 CEP07548.1 - 2.1e-83 278.9 63.9 7.7e-46 156.2 20.1 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEP07548.1 - 2.3e-35 122.1 0.1 3e-18 66.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CEP07548.1 - 2.5e-25 88.2 9.0 5.9e-19 67.8 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP07548.1 - 2.6e-14 53.6 0.0 8.4e-14 52.0 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CEP07548.1 - 1.8e-09 37.2 47.1 6.3e-08 32.1 12.5 2.7 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 CEP07548.1 - 1.5e-05 25.5 0.1 0.029 14.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 CEP07548.1 - 2.3e-05 24.4 0.7 0.14 11.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEP07548.1 - 4.5e-05 23.4 0.5 0.0031 17.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CEP07548.1 - 6.4e-05 22.6 0.0 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEP07548.1 - 0.00058 19.5 0.9 0.02 14.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CEP07548.1 - 0.0033 18.0 0.1 0.16 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP07548.1 - 0.015 15.6 0.0 1.6 9.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CEP07548.1 - 0.041 13.6 0.7 3 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEP07548.1 - 0.055 13.0 0.5 0.93 9.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEP07548.1 - 0.063 13.2 0.6 2.9 7.8 0.1 2.8 3 0 0 3 3 3 0 NACHT domain FEZ PF07763.13 CEP07548.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 FEZ-like protein AAA_23 PF13476.6 CEP07548.1 - 0.37 11.3 2.6 0.58 10.6 0.1 2.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CEP07548.1 - 0.39 10.5 1.3 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CEP07548.1 - 0.39 10.7 1.9 4.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CEP07548.1 - 0.64 10.2 1.7 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CEP07548.1 - 6.5 5.9 24.1 0.11 11.7 2.5 3.0 4 0 0 4 4 4 0 ABC-2 family transporter protein Aldedh PF00171.22 CEP07549.1 - 2.3e-133 445.1 0.0 2.8e-133 444.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.28 CEP07549.1 - 1.6e-06 28.0 0.1 3.2e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CEP07549.1 - 0.03 14.2 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 Peptidase dimerisation domain DUF1505 PF07403.11 CEP07550.1 - 0.076 13.2 0.2 0.079 13.1 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) FAT PF02259.23 CEP07551.1 - 2.8e-72 243.8 10.9 2.8e-72 243.8 10.9 2.9 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 CEP07551.1 - 2.1e-29 103.1 1.4 2.1e-29 103.1 1.4 2.4 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEP07551.1 - 2.4e-05 24.1 0.9 5.5e-05 22.9 0.9 1.7 1 0 0 1 1 1 1 FATC domain RIX1 PF08167.12 CEP07551.1 - 0.015 15.1 1.2 0.32 10.7 0.0 4.2 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis F-box-like PF12937.7 CEP07552.1 - 1e-07 31.7 0.2 3.1e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07552.1 - 0.0013 18.6 0.1 0.0048 16.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF226 PF02890.14 CEP07552.1 - 0.013 15.5 0.6 0.013 15.5 0.6 2.3 2 1 1 3 3 3 0 Borrelia family of unknown function DUF226 Pentapeptide_4 PF13599.6 CEP07552.1 - 0.095 12.9 2.7 0.36 11.0 0.3 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) F-box-like PF12937.7 CEP07554.1 - 0.00027 20.8 0.6 0.00081 19.2 0.2 2.0 2 0 0 2 2 2 1 F-box-like Stk19 PF10494.9 CEP07554.1 - 0.14 11.8 0.1 2.5 7.7 0.1 2.1 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 Svf1_C PF17187.4 CEP07555.1 - 6.3e-51 172.5 2.3 1e-50 171.8 2.3 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CEP07555.1 - 8.9e-33 113.7 0.9 2e-32 112.5 0.9 1.6 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain UPF0020 PF01170.18 CEP07556.1 - 1.3e-10 41.3 0.0 7.4e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 CEP07556.1 - 0.00042 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CEP07556.1 - 0.0032 17.2 0.0 1.1 8.9 0.0 2.6 2 1 1 3 3 3 2 DNA methylase DUF4477 PF14780.6 CEP07557.1 - 4.5e-19 68.8 3.7 8.2e-19 68.0 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) F-box-like PF12937.7 CEP07558.1 - 1.2e-08 34.7 0.4 3.5e-08 33.2 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07558.1 - 0.004 17.0 2.6 0.0051 16.7 0.4 2.4 2 0 0 2 2 2 1 F-box domain APG17 PF04108.12 CEP07558.1 - 0.21 10.7 3.4 6.4 5.8 0.8 2.4 2 0 0 2 2 2 0 Autophagy protein Apg17 DED PF01335.21 CEP07558.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.8 3 0 0 3 3 3 0 Death effector domain SDH_alpha PF03313.15 CEP07559.1 - 1.7e-104 349.1 0.1 2.5e-104 348.6 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CEP07559.1 - 1.6e-58 197.5 0.0 3.4e-58 196.4 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain HIT PF01230.23 CEP07560.1 - 4.3e-13 49.8 0.0 5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CEP07560.1 - 7e-06 26.5 0.0 7.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CEP07560.1 - 0.00099 19.0 0.1 0.0012 18.8 0.1 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 E1-E2_ATPase PF00122.20 CEP07561.1 - 2.2e-47 160.9 1.3 5.6e-47 159.6 1.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP07561.1 - 4.5e-22 78.6 6.9 9.6e-15 54.7 2.4 2.8 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP07561.1 - 1.7e-19 69.7 0.0 4.2e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP07561.1 - 2.1e-17 64.1 0.0 3.5e-15 56.9 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP07561.1 - 2.1e-07 30.5 0.0 4.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP07561.1 - 0.00016 21.5 0.8 0.046 13.4 0.8 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase MRNIP PF15749.5 CEP07562.1 - 4.8 7.9 7.3 14 6.5 7.4 1.6 1 1 0 1 1 1 0 MRN-interacting protein zf-CCHC PF00098.23 CEP07564.1 - 6.2e-05 22.9 2.0 9.2e-05 22.3 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEP07564.1 - 0.00079 19.3 0.2 0.0015 18.4 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DDE_3 PF13358.6 CEP07565.1 - 0.063 13.0 0.4 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease CTP_transf_like PF01467.26 CEP07566.1 - 8.4e-29 100.6 0.0 2e-28 99.3 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF5639 PF18690.1 CEP07566.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5639) ORC6 PF05460.13 CEP07566.1 - 1.9 7.7 7.9 3.6 6.8 4.3 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) UQ_con PF00179.26 CEP07567.1 - 1.3e-11 44.3 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP07567.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain TFIIA PF03153.13 CEP07568.1 - 0.32 10.9 54.0 0.44 10.5 54.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACOX PF01756.19 CEP07569.1 - 2.5e-50 170.5 0.1 5.2e-50 169.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEP07569.1 - 4.9e-29 101.4 0.3 9.1e-29 100.5 0.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEP07569.1 - 9.7e-15 54.5 0.0 2.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP07569.1 - 0.00022 21.5 0.0 0.0013 18.9 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEP07569.1 - 0.0016 19.1 0.0 0.0051 17.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain PXA PF02194.15 CEP07570.1 - 4.9e-46 157.0 1.7 1.6e-45 155.3 0.7 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CEP07570.1 - 1.5e-27 96.4 0.3 1.5e-27 96.4 0.3 2.8 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CEP07570.1 - 6.1e-20 71.3 0.0 2.6e-19 69.3 0.0 2.2 1 0 0 1 1 1 1 PX domain RGS PF00615.19 CEP07570.1 - 8.9e-13 48.5 4.3 8.9e-13 48.5 4.3 3.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain Rbsn PF11464.8 CEP07570.1 - 0.0015 18.2 3.1 0.0051 16.5 3.1 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Isy1 PF06246.12 CEP07570.1 - 0.0035 17.0 0.6 0.0035 17.0 0.6 3.1 4 0 0 4 4 4 1 Isy1-like splicing family Pkinase PF00069.25 CEP07572.1 - 1.1e-22 80.7 0.0 1.8e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07572.1 - 6.6e-22 78.0 0.0 8.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_C14 PF00656.22 CEP07573.1 - 8.6e-54 183.1 0.0 1.3e-53 182.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.7 CEP07574.1 - 3.2e-19 69.3 1.4 1.6e-09 38.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP07574.1 - 2.5e-14 52.0 0.6 0.00021 21.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 CEP07574.1 - 3.7e-14 52.9 0.1 4e-05 24.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP07574.1 - 9.3e-13 48.1 0.7 1.8e-05 24.9 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CEP07574.1 - 3.8e-10 39.7 4.4 0.0077 16.6 0.1 4.9 5 0 0 5 5 5 3 Ankyrin repeat Myosin_head PF00063.21 CEP07575.1 - 4e-14 51.8 0.1 4.5e-14 51.6 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) SNF2_N PF00176.23 CEP07576.1 - 7.9e-52 176.1 0.9 2.2e-50 171.3 0.2 2.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP07576.1 - 4.7e-17 62.3 0.2 2e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEP07576.1 - 1.6e-12 47.3 0.6 7.1e-12 45.1 0.6 2.1 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CEP07576.1 - 3.9e-07 30.2 0.6 1.6e-06 28.3 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Chromo PF00385.24 CEP07576.1 - 7.9e-07 28.9 2.3 1.4e-06 28.1 0.2 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 CEP07576.1 - 1.3e-05 25.0 14.8 0.00014 21.7 2.1 2.5 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 CEP07576.1 - 4.5e-05 23.3 16.5 0.00077 19.3 4.5 3.0 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Cuticle_3 PF11018.8 CEP07576.1 - 0.011 16.0 12.2 0.027 14.7 12.2 1.6 1 0 0 1 1 1 0 Pupal cuticle protein C1 BtrH_N PF14399.6 CEP07576.1 - 0.022 15.0 0.2 0.061 13.6 0.2 1.7 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal PHD_4 PF16866.5 CEP07576.1 - 0.16 12.0 14.9 0.17 12.0 3.1 3.0 2 0 0 2 2 2 0 PHD-finger SUIM_assoc PF16619.5 CEP07576.1 - 0.21 11.7 0.1 0.21 11.7 0.1 4.2 4 0 0 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 NTP_transferase PF00483.23 CEP07577.1 - 5.5e-51 173.5 0.0 8.4e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEP07577.1 - 1.1e-12 47.1 10.4 1.4e-10 40.5 3.1 3.5 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEP07577.1 - 1.2e-09 38.8 0.0 1.6e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CEP07577.1 - 7.3e-05 22.4 4.1 7.3e-05 22.4 4.1 3.3 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CEP07577.1 - 0.03 12.5 0.3 0.042 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CEP07577.1 - 0.13 11.2 0.1 0.42 9.5 0.1 1.8 2 1 0 2 2 2 0 L-fucokinase CTP_transf_3 PF02348.19 CEP07577.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Bact_lectin PF18483.1 CEP07579.1 - 1.8e-16 60.7 0.0 4.6e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEP07579.1 - 1.1e-15 57.9 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 CEP07579.1 - 4.8e-13 49.6 0.1 1.2e-12 48.3 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CEP07579.1 - 3.2e-12 46.4 0.8 6.4e-12 45.4 0.8 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Lectin_leg-like PF03388.13 CEP07579.1 - 7.3e-07 28.8 0.0 0.022 14.1 0.0 2.4 2 0 0 2 2 2 2 Legume-like lectin family PAW PF04721.17 CEP07579.1 - 0.00074 19.3 0.3 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW zf-RVT PF13966.6 CEP07581.1 - 0.00029 21.5 0.8 0.00065 20.4 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP07583.1 - 2e-21 76.6 0.0 6.8e-21 74.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1d PF00750.19 CEP07584.1 - 1.4e-90 303.8 1.2 1.6e-90 303.5 1.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CEP07584.1 - 9.5e-24 83.9 0.1 2e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain RRM_1 PF00076.22 CEP07585.1 - 7.3e-16 57.8 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 CEP07585.1 - 1.9e-15 56.6 0.0 6e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 CEP07585.1 - 3.3e-05 24.6 0.4 7.7e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 CEP07585.1 - 0.0071 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CEP07585.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP07585.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Asn_synthase PF00733.21 CEP07586.1 - 1.4e-18 67.7 0.4 1.3e-08 35.0 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 CEP07586.1 - 3.1e-06 27.1 0.0 1.1e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEP07586.1 - 0.093 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Aluminium induced protein NUDIX PF00293.28 CEP07587.1 - 7.1e-12 45.5 0.0 8.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Nucleopor_Nup85 PF07575.13 CEP07589.1 - 1.3e-42 146.1 9.2 2.5e-42 145.2 9.2 1.4 1 1 0 1 1 1 1 Nup85 Nucleoporin Dynactin PF12455.8 CEP07590.1 - 3.7e-89 298.8 13.6 3.7e-89 298.8 13.6 4.8 4 1 1 5 5 5 1 Dynein associated protein RRM_1 PF00076.22 CEP07592.1 - 5.4e-07 29.3 0.1 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer PF06495.11 CEP07592.1 - 0.00082 19.5 21.1 0.00082 19.5 21.1 1.9 2 0 0 2 2 2 1 Fruit fly transformer protein RSRP PF17069.5 CEP07592.1 - 0.37 10.3 31.4 0.98 8.9 31.4 1.7 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 GREB1 PF15782.5 CEP07592.1 - 9 3.3 14.8 13 2.7 14.8 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3_PI4_kinase PF00454.27 CEP07593.1 - 5.8e-40 137.7 0.0 6.6e-38 130.9 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEP07593.1 - 4.5e-23 81.6 0.0 1.3e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HTH_32 PF13565.6 CEP07597.1 - 6.3e-07 29.9 0.0 2.5e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CEP07597.1 - 0.0014 18.3 1.8 0.094 12.5 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CEP07597.1 - 0.0033 17.5 5.5 0.046 13.9 0.1 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain Receptor_2B4 PF11465.8 CEP07597.1 - 0.06 13.6 0.3 0.21 11.8 0.1 2.0 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Octopine_DH PF02317.17 CEP07597.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain HTH_17 PF12728.7 CEP07597.1 - 1.2 9.3 3.1 25 5.2 0.0 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain Aminotran_3 PF00202.21 CEP07598.1 - 7.3e-121 403.6 0.0 8.3e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Mlh1_C PF16413.5 CEP07599.1 - 1.2e-81 274.1 3.0 4.4e-79 265.7 2.9 2.5 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CEP07599.1 - 2.8e-32 110.9 0.0 5.2e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEP07599.1 - 7.3e-12 45.3 0.1 2e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEP07599.1 - 2.3e-06 28.1 0.1 5.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAF1 PF04857.20 CEP07599.1 - 0.048 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease COG5 PF10392.9 CEP07600.1 - 0.084 13.1 3.7 0.12 12.5 0.4 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF641 PF04859.12 CEP07600.1 - 0.29 11.5 4.5 0.4 11.0 1.0 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 CEP07600.1 - 0.36 11.3 4.4 0.18 12.2 1.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CorA PF01544.18 CEP07601.1 - 2.6e-46 158.3 0.0 3.9e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EF-hand_1 PF00036.32 CEP07602.1 - 1.2e-36 121.5 15.5 6.5e-10 37.8 0.5 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP07602.1 - 1.7e-33 114.9 4.5 2.6e-18 66.2 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP07602.1 - 4.5e-28 94.7 10.5 9.7e-09 34.5 0.1 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CEP07602.1 - 3.1e-27 94.2 14.7 8.9e-16 57.5 1.4 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEP07602.1 - 1.5e-26 90.7 15.6 5.1e-08 32.1 0.3 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEP07602.1 - 5.6e-14 52.2 0.0 6.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEP07602.1 - 1.7e-09 37.6 3.1 0.001 19.0 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEP07602.1 - 2.5e-08 34.2 0.2 0.00039 20.7 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CEP07602.1 - 0.00016 21.8 9.7 0.13 12.4 0.5 3.3 1 1 3 4 4 4 4 Dockerin type I domain TerB PF05099.13 CEP07602.1 - 0.00056 19.9 0.2 0.051 13.5 0.1 2.4 1 1 2 3 3 3 1 Tellurite resistance protein TerB EF-hand_11 PF08976.11 CEP07602.1 - 0.011 16.5 0.0 0.046 14.6 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 CEP07602.1 - 0.014 15.3 0.6 1.1 9.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N_3 PF13624.6 CEP07602.1 - 0.023 14.5 0.2 0.65 9.8 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain UPF0154 PF03672.13 CEP07602.1 - 0.034 14.2 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 CEP07602.1 - 0.037 14.0 1.0 1.3 8.9 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein DUF2267 PF10025.9 CEP07602.1 - 0.037 14.3 0.1 0.054 13.8 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) EF-hand_14 PF17959.1 CEP07602.1 - 0.11 12.8 0.1 0.83 10.0 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain Ribosomal_S3Ae PF01015.18 CEP07603.1 - 1.4e-73 246.8 4.6 1.6e-73 246.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family F-box-like PF12937.7 CEP07604.1 - 4.1e-10 39.4 0.3 8.9e-10 38.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07604.1 - 2.2e-07 30.6 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 CEP07604.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box SelP_N PF04592.14 CEP07604.1 - 0.3 10.4 5.1 0.47 9.8 5.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF5040 PF16443.5 CEP07605.1 - 0.13 11.6 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) IQ PF00612.27 CEP07606.1 - 4.9e-06 25.9 0.6 1.1e-05 24.8 0.6 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif CAT PF00302.18 CEP07606.1 - 0.051 13.5 0.8 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Chloramphenicol acetyltransferase Lzipper-MIP1 PF14389.6 CEP07606.1 - 0.12 12.7 23.2 0.039 14.2 3.2 4.3 1 1 3 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 betaPIX_CC PF16523.5 CEP07606.1 - 1.5 8.7 15.7 0.18 11.6 1.4 3.7 1 1 2 3 3 3 0 betaPIX coiled coil DUF3332 PF11810.8 CEP07606.1 - 3.1 7.4 6.9 1.7 8.3 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) Jnk-SapK_ap_N PF09744.9 CEP07606.1 - 6.3 7.0 26.6 0.19 12.0 13.4 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 CEP07606.1 - 7.3 7.4 18.7 0.16 12.7 7.0 3.6 2 1 2 4 4 4 0 Occludin homology domain DUF4446 PF14584.6 CEP07606.1 - 9.1 6.2 12.4 0.65 10.0 3.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) MFS_1 PF07690.16 CEP07608.1 - 7.9e-24 84.2 41.4 7.9e-24 84.2 41.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07609.1 - 1.1e-102 344.3 28.3 1.2e-51 176.0 3.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP07609.1 - 2.1e-29 102.6 13.8 2.1e-29 102.6 13.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 CEP07610.1 - 4.6e-20 71.2 0.2 3.6e-15 55.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_memb PF02932.16 CEP07610.1 - 0.014 15.5 7.9 0.023 14.8 7.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2464 PF10240.9 CEP07610.1 - 0.028 14.0 8.3 0.081 12.5 8.3 1.7 1 0 0 1 1 1 0 Multivesicular body subunit 12 PAT1 PF09770.9 CEP07610.1 - 0.043 12.1 29.8 0.07 11.4 29.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.12 CEP07610.1 - 0.059 13.6 15.5 0.1 12.9 15.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 CEP07610.1 - 0.087 9.9 18.0 0.13 9.3 18.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 CEP07610.1 - 0.16 11.3 14.3 0.24 10.7 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 CEP07610.1 - 0.24 10.3 19.6 0.37 9.7 19.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PA26 PF04636.13 CEP07610.1 - 0.25 10.2 14.5 0.45 9.4 14.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 CEP07610.1 - 0.29 9.2 14.7 0.38 8.8 14.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIEZO PF15917.5 CEP07610.1 - 0.35 10.3 21.8 0.63 9.5 21.8 1.3 1 0 0 1 1 1 0 Piezo Membralin PF09746.9 CEP07610.1 - 0.36 9.8 11.4 0.73 8.8 11.4 1.4 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 CEP07610.1 - 0.57 9.0 5.4 0.81 8.5 5.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) SpoIIP PF07454.11 CEP07610.1 - 1 8.8 17.1 2.1 7.8 17.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 CEP07610.1 - 1.3 8.0 18.9 2.1 7.2 18.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 CEP07610.1 - 1.3 7.7 16.0 2.2 7.0 16.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 CEP07610.1 - 1.6 6.7 17.9 2.3 6.2 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 CEP07610.1 - 1.6 7.4 22.5 2.7 6.7 22.5 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CEP07610.1 - 1.6 7.8 5.5 2.1 7.5 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CEP07610.1 - 2 8.1 18.1 3.3 7.5 18.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 CEP07610.1 - 2.8 7.4 28.1 0.16 11.5 22.0 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.6 CEP07610.1 - 2.8 7.9 16.4 6.7 6.7 16.4 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Nop53 PF07767.11 CEP07610.1 - 3.6 6.9 27.2 5.2 6.4 27.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PepSY_TM PF03929.16 CEP07610.1 - 3.8 7.1 7.6 7.7 6.1 7.6 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Hydin_ADK PF17213.3 CEP07610.1 - 3.9 7.7 26.5 0.047 14.0 15.7 2.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Pet20 PF08692.10 CEP07610.1 - 7.2 7.3 10.8 2.8 8.7 7.8 1.9 2 0 0 2 2 1 0 Mitochondrial protein Pet20 UPF0560 PF10577.9 CEP07610.1 - 8.1 4.8 29.3 16 3.8 29.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.13 CEP07610.1 - 8.8 6.0 17.4 20 4.9 17.4 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LMBR1 PF04791.16 CEP07610.1 - 9 5.1 9.8 12 4.7 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cellulose_synt PF03552.14 CEP07610.1 - 10 4.5 7.0 15 4.0 7.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Ank_4 PF13637.6 CEP07611.1 - 5e-21 74.8 1.6 2.8e-10 40.5 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP07611.1 - 4.2e-14 52.9 0.4 4.2e-08 33.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP07611.1 - 8.3e-11 41.1 1.4 0.012 16.1 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CEP07611.1 - 1.4e-09 38.0 0.4 8.9e-06 25.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP07611.1 - 7.3e-08 32.5 5.2 0.0074 16.7 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Cytochrom_C_2 PF01322.20 CEP07613.1 - 0.17 12.8 1.5 0.51 11.2 1.5 1.9 1 0 0 1 1 1 0 Cytochrome C' Fer4_2 PF12797.7 CEP07613.1 - 0.69 10.1 2.1 1.4 9.2 2.1 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain AAA_17 PF13207.6 CEP07613.1 - 1.1 9.6 4.1 8.9 6.7 0.8 2.9 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 CEP07614.1 - 1e-19 70.5 11.5 0.00023 21.9 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07614.1 - 6e-11 42.5 0.2 0.00032 20.9 0.1 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP07614.1 - 5.3e-05 22.1 1.0 0.0021 16.8 0.0 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP07614.1 - 0.00074 18.6 1.5 6.6 5.6 0.0 3.8 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CEP07614.1 - 0.0071 15.4 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Hira PF07569.11 CEP07614.1 - 0.031 14.0 1.0 1.2 8.8 0.0 3.1 4 0 0 4 4 4 0 TUP1-like enhancer of split PPP4R2 PF09184.11 CEP07614.1 - 0.15 11.7 9.6 0.2 11.2 9.6 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 CEP07614.1 - 0.18 11.1 10.7 0.25 10.6 10.7 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 CEP07614.1 - 0.68 9.6 15.0 1.2 8.9 15.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAM_decarbox PF01536.16 CEP07615.1 - 2.3e-125 418.3 0.0 5.6e-125 417.0 0.0 1.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Glyco_transf_49 PF13896.6 CEP07616.1 - 1.5e-60 205.3 5.4 1.2e-47 162.9 1.9 3.2 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan DUF3336 PF11815.8 CEP07616.1 - 8.4e-27 93.6 4.0 1.9e-26 92.4 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEP07616.1 - 5.3e-17 62.7 0.0 1.4e-16 61.3 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1804 PF08822.11 CEP07616.1 - 0.11 12.5 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Glyco_tranf_2_4 PF13704.6 CEP07616.1 - 0.21 12.1 1.0 0.6 10.7 0.3 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 HLH PF00010.26 CEP07617.1 - 7.3e-17 61.1 0.5 7.3e-17 61.1 0.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DNA_pol_phi PF04931.13 CEP07617.1 - 0.014 13.5 4.7 0.019 13.1 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CEP07617.1 - 3.4 5.8 9.9 4.7 5.4 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 CEP07619.1 - 0.0022 18.0 13.7 0.003 17.6 1.2 2.3 2 0 0 2 2 2 2 Zinc knuckle GAGA PF09237.11 CEP07621.1 - 0.012 15.4 1.3 0.019 14.7 1.3 1.3 1 0 0 1 1 1 0 GAGA factor Chromo PF00385.24 CEP07623.1 - 6.5e-10 38.8 1.0 1.1e-09 38.0 1.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 CEP07623.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 DDE_3 PF13358.6 CEP07624.1 - 0.017 14.9 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Phage_CI_repr PF07022.13 CEP07625.1 - 0.015 15.3 0.5 0.057 13.5 0.2 2.0 1 1 1 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DDE_Tnp_1_7 PF13843.6 CEP07628.1 - 1.4e-41 143.0 0.0 1.5e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_5 PF13546.6 CEP07628.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2075 PF09848.9 CEP07630.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CEP07630.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP07630.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP07630.1 - 0.02 14.6 0.1 0.039 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CEP07630.1 - 0.04 13.6 1.6 0.096 12.4 0.5 2.0 1 1 1 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 CEP07630.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CEP07630.1 - 0.051 12.6 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 CEP07630.1 - 0.063 13.0 0.1 0.14 11.9 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CEP07630.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 CEP07630.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF815 PF05673.13 CEP07630.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 CEP07630.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF463 PF04317.12 CEP07630.1 - 0.11 11.3 0.3 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 MeaB PF03308.16 CEP07630.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 CEP07630.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1601 PF07671.11 CEP07632.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) PP2C PF00481.21 CEP07634.1 - 2.8e-52 177.9 0.0 4.6e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CEP07634.1 - 1.4e-38 130.4 64.4 8.2e-08 31.9 7.9 10.6 5 3 9 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 CEP07634.1 - 1.6e-37 126.9 68.9 5.1e-07 29.9 0.5 12.5 6 3 9 15 15 15 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CEP07634.1 - 1.8e-29 102.7 0.1 7e-29 100.8 0.0 2.0 2 1 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 CEP07634.1 - 2.8e-06 27.9 0.0 7.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 CEP07634.1 - 0.01 15.4 20.3 0.29 10.6 0.5 5.2 2 1 0 4 4 4 0 Leucine-rich repeat LRR_5 PF13306.6 CEP07634.1 - 0.041 13.8 1.4 1.4 8.9 0.3 3.3 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF4844 PF16133.5 CEP07634.1 - 0.066 13.8 0.9 0.24 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) PP2C_2 PF13672.6 CEP07634.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_1 PF00560.33 CEP07634.1 - 0.18 12.5 62.9 0.92 10.3 0.1 16.3 19 1 0 19 19 19 0 Leucine Rich Repeat Pkinase PF00069.25 CEP07635.1 - 5e-60 203.1 0.0 1.1e-59 202.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07635.1 - 1.7e-45 155.4 0.0 2.7e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP07635.1 - 8.7e-08 31.3 0.0 2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP07635.1 - 3.1e-06 26.7 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ADIP PF11559.8 CEP07635.1 - 0.00055 20.1 3.4 0.0011 19.1 3.4 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 CEP07635.1 - 0.00083 19.2 1.3 0.0015 18.4 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) ABC1 PF03109.16 CEP07635.1 - 0.0067 16.6 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 ABC1 family bZIP_1 PF00170.21 CEP07635.1 - 0.029 14.4 1.6 0.065 13.3 1.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor RNase_T PF00929.24 CEP07635.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Exonuclease Haspin_kinase PF12330.8 CEP07635.1 - 0.063 12.2 3.3 0.093 11.7 0.1 2.4 2 1 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 CEP07635.1 - 0.1 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family YabA PF06156.13 CEP07635.1 - 0.31 11.7 3.1 0.28 11.8 1.3 2.0 2 0 0 2 2 1 0 Initiation control protein YabA DivIC PF04977.15 CEP07635.1 - 0.42 10.4 6.7 0.48 10.2 3.4 2.4 2 0 0 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CEP07635.1 - 1.1 9.6 5.0 0.41 11.1 1.5 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 CEP07635.1 - 1.2 9.6 3.8 0.77 10.2 0.6 2.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 CEP07635.1 - 1.9 8.5 10.2 7.1 6.7 10.2 2.0 1 0 0 1 1 1 0 FlxA-like protein ZapB PF06005.12 CEP07635.1 - 3.7 8.1 10.5 0.49 10.9 5.7 2.0 2 0 0 2 2 2 0 Cell division protein ZapB Kelch_3 PF13415.6 CEP07637.1 - 1.1e-41 140.4 9.6 1.8e-08 34.5 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP07637.1 - 4.7e-39 131.7 9.2 3.6e-08 32.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CEP07637.1 - 3.1e-37 126.3 10.5 3.3e-07 30.2 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP07637.1 - 5.9e-37 124.8 12.7 6.6e-09 35.7 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.6 CEP07637.1 - 3.6e-36 122.6 7.2 1.7e-08 34.2 0.6 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CEP07637.1 - 1.7e-31 106.9 16.6 1e-05 25.3 0.2 7.0 7 0 0 7 7 7 6 Kelch motif PQQ_3 PF13570.6 CEP07637.1 - 4.8e-05 23.7 1.9 4.1 8.0 0.0 4.7 4 0 0 4 4 4 2 PQQ-like domain ABC_membrane PF00664.23 CEP07638.1 - 2.3e-62 211.1 4.5 2.3e-62 211.1 4.5 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEP07638.1 - 9.4e-38 129.8 0.0 2e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CEP07638.1 - 8.7e-06 25.3 1.2 0.0062 16.0 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP07638.1 - 0.00039 20.7 0.2 0.0056 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP07638.1 - 0.0018 18.7 0.0 0.0066 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEP07638.1 - 0.0062 16.3 0.2 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CEP07638.1 - 0.056 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP07638.1 - 0.076 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CEP07638.1 - 0.079 12.7 0.0 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase PAS_5 PF07310.13 CEP07638.1 - 0.087 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 PAS domain AAA_24 PF13479.6 CEP07638.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Med22 PF06179.12 CEP07639.1 - 2.1e-23 82.5 4.3 2.5e-23 82.3 4.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Ead_Ea22 PF13935.6 CEP07639.1 - 0.12 13.0 1.0 4 8.1 1.4 2.0 1 1 1 2 2 2 0 Ead/Ea22-like protein PP2C PF00481.21 CEP07641.1 - 1.8e-51 175.2 0.0 1.4e-48 165.8 0.0 2.7 1 1 0 1 1 1 1 Protein phosphatase 2C COOH-NH2_lig PF14395.6 CEP07641.1 - 0.096 11.9 0.1 15 4.7 0.0 3.1 3 1 1 4 4 4 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Fcf1 PF04900.12 CEP07642.1 - 1.3e-39 134.5 1.1 2.7e-39 133.5 1.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CEP07642.1 - 1.4e-11 44.7 0.7 4e-11 43.2 0.0 1.9 2 1 1 3 3 3 1 PIN like domain DUF116 PF01976.17 CEP07642.1 - 0.026 14.0 0.6 0.042 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 Chromo PF00385.24 CEP07644.1 - 9.1e-10 38.3 0.9 1.9e-09 37.3 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S1_2 PF13509.6 CEP07644.1 - 0.079 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 S1 domain Mt_ATP-synt_D PF05873.12 CEP07645.1 - 1.6e-21 76.8 2.9 1.8e-21 76.6 2.9 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) 120_Rick_ant PF12574.8 CEP07645.1 - 0.0012 18.1 0.6 0.0012 18.1 0.6 1.4 2 0 0 2 2 2 1 120 KDa Rickettsia surface antigen RPW8 PF05659.11 CEP07645.1 - 0.0021 17.8 1.7 0.012 15.3 0.5 2.4 2 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 CEP07645.1 - 0.01 15.9 1.1 0.013 15.5 1.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF327 PF03885.13 CEP07645.1 - 0.014 15.4 3.4 0.21 11.6 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF327) Prominin PF05478.11 CEP07645.1 - 0.023 12.7 3.2 0.027 12.5 3.2 1.0 1 0 0 1 1 1 0 Prominin Pet20 PF08692.10 CEP07645.1 - 0.025 15.3 0.2 0.043 14.5 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial protein Pet20 DUF4600 PF15372.6 CEP07645.1 - 0.025 15.0 4.3 2.9 8.3 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CdvA PF18822.1 CEP07645.1 - 0.026 14.4 1.9 0.25 11.2 0.6 2.2 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Vps51 PF08700.11 CEP07645.1 - 0.038 14.1 1.8 7.8 6.7 1.8 2.5 1 1 0 1 1 1 0 Vps51/Vps67 BLOC1_2 PF10046.9 CEP07645.1 - 0.046 14.0 3.6 0.98 9.8 0.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 CEP07645.1 - 0.05 14.2 3.1 0.12 13.0 0.9 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF5446 PF17522.2 CEP07645.1 - 0.055 13.6 0.1 0.055 13.6 0.1 2.3 3 0 0 3 3 2 0 Family of unknown function (DUF5446) TMPIT PF07851.13 CEP07645.1 - 0.056 12.7 2.6 0.067 12.4 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 CEP07645.1 - 0.088 12.8 3.4 0.33 11.0 2.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 CEP07645.1 - 0.16 12.1 1.4 0.27 11.4 0.3 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF148 PF02520.17 CEP07645.1 - 0.22 11.7 6.5 0.18 11.9 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 Laminin_II PF06009.12 CEP07645.1 - 0.23 11.5 5.8 0.31 11.1 2.4 2.4 1 1 2 3 3 3 0 Laminin Domain II Rx_N PF18052.1 CEP07645.1 - 0.24 11.7 2.6 1.1 9.5 0.2 2.4 1 1 0 2 2 2 0 Rx N-terminal domain DUF16 PF01519.16 CEP07645.1 - 0.6 10.6 5.1 1.3 9.6 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.11 CEP07645.1 - 1.2 9.4 4.8 2.5 8.4 1.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CEP07645.1 - 3.1 8.3 8.5 84 3.7 8.5 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HIP1_clath_bdg PF16515.5 CEP07645.1 - 5.2 7.7 8.8 9 7.0 2.7 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PQ-loop PF04193.14 CEP07646.1 - 5.1e-19 67.8 16.7 1.1e-17 63.5 3.3 3.3 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CEP07646.1 - 0.0051 16.8 0.4 0.0051 16.8 0.4 2.9 3 1 0 3 3 3 1 Sugar efflux transporter for intercellular exchange FliD_N PF02465.18 CEP07646.1 - 0.029 15.1 5.1 0.045 14.4 5.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus COX6A PF02046.15 CEP07646.1 - 0.097 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa S1FA PF04689.13 CEP07646.1 - 0.24 11.6 1.8 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 DNA binding protein S1FA PAT1 PF09770.9 CEP07647.1 - 1.1e-134 450.7 46.3 3.2e-122 409.5 26.9 2.2 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 YqzH PF14164.6 CEP07647.1 - 0.1 12.7 1.1 2.2 8.4 0.0 3.5 4 0 0 4 4 4 0 YqzH-like protein Lipase_GDSL_2 PF13472.6 CEP07648.1 - 0.00057 20.3 0.2 0.0012 19.3 0.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEP07648.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ribosomal_L6e PF01159.19 CEP07649.1 - 6.8e-39 132.9 0.2 6.8e-39 132.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CEP07649.1 - 3.3e-10 40.1 1.2 3.3e-10 40.1 1.2 2.3 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain F-box-like PF12937.7 CEP07650.1 - 0.00016 21.5 0.3 0.0005 19.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like Transket_pyr PF02779.24 CEP07651.1 - 6.7e-45 152.9 0.1 1.2e-44 152.2 0.1 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEP07651.1 - 7.8e-36 122.7 0.0 2.1e-35 121.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain MMtag PF10159.9 CEP07652.1 - 7.5e-34 115.9 2.1 7.5e-34 115.9 2.1 3.4 2 1 0 2 2 2 1 Multiple myeloma tumor-associated MFS_5 PF05631.14 CEP07653.1 - 2.4e-75 253.7 8.6 3.1e-75 253.3 8.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CEP07653.1 - 1.6e-18 66.8 29.3 2.2e-18 66.3 29.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ECF-ribofla_trS PF07155.12 CEP07653.1 - 0.0033 17.4 4.9 0.0033 17.4 4.9 2.5 1 1 0 2 2 2 1 ECF-type riboflavin transporter, S component MFS_1_like PF12832.7 CEP07653.1 - 0.55 9.0 18.6 2e+02 0.6 18.6 3.8 1 1 0 1 1 1 0 MFS_1 like family Ribosomal_L4 PF00573.22 CEP07654.1 - 5.8e-69 231.6 0.0 7.3e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DEAD PF00270.29 CEP07655.1 - 1.4e-43 148.7 0.0 2.2e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP07655.1 - 1.9e-30 105.4 0.0 7.6e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RanBP PF00641.18 CEP07655.1 - 8.3e-27 92.2 24.4 6.4e-10 38.2 2.4 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others UTP25 PF06862.12 CEP07655.1 - 0.042 12.6 0.0 7 5.3 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 CEP07655.1 - 0.049 13.6 0.0 0.42 10.6 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DZR PF12773.7 CEP07655.1 - 0.16 12.0 15.2 0.54 10.3 7.4 2.6 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_C PF00034.21 CEP07655.1 - 0.61 11.3 4.5 0.74 11.0 0.4 3.3 3 0 0 3 3 3 0 Cytochrome c Rubredoxin PF00301.20 CEP07655.1 - 4.2 7.5 16.7 0.73 9.9 0.3 3.7 3 1 1 4 4 4 0 Rubredoxin Pkinase PF00069.25 CEP07656.1 - 9.9e-27 93.9 0.0 1.7e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07656.1 - 1.2e-24 87.0 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP07656.1 - 0.088 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.15 CEP07657.1 - 4.8e-10 39.5 0.9 1.3e-09 38.1 0.9 1.8 1 1 0 1 1 1 1 Multicopper oxidase CRAL_TRIO PF00650.20 CEP07659.1 - 1.9e-36 125.2 0.0 2.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP07659.1 - 3.9e-11 43.0 1.2 6e-11 42.4 0.0 2.1 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEP07659.1 - 6.2e-06 26.4 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RRP36 PF06102.12 CEP07660.1 - 1.8e-49 167.9 31.5 1.8e-49 167.9 31.5 2.5 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF1748 PF08520.10 CEP07661.1 - 3e-29 100.7 0.0 3.4e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WRKY PF03106.15 CEP07663.1 - 4.1e-08 33.3 4.3 1.1e-07 31.9 4.3 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain Ribosomal_L27e PF01777.18 CEP07664.1 - 4e-37 126.4 7.1 4e-37 126.4 7.1 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CEP07664.1 - 0.0027 17.6 6.5 0.0071 16.3 6.5 2.0 1 1 0 1 1 1 1 KOW motif Ribosomal_S2 PF00318.20 CEP07665.1 - 9.8e-24 83.8 0.5 3.9e-13 49.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Tfb2 PF03849.14 CEP07666.1 - 9.7e-143 475.4 6.0 1.2e-142 475.2 6.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CEP07666.1 - 8.3e-27 93.4 0.2 1.9e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CEP07666.1 - 0.00034 20.8 0.0 0.00071 19.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SlpA PF03217.14 CEP07667.1 - 6.1 7.5 8.3 0.71 10.5 2.1 2.4 2 0 0 2 2 2 0 Surface later protein A domain Phage_int_SAM_1 PF02899.17 CEP07669.1 - 0.00017 21.8 0.6 0.00048 20.4 0.3 1.9 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP07669.1 - 0.0043 17.5 0.3 0.017 15.6 0.1 2.1 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Aconitase_B_N PF11791.8 CEP07669.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain gag-asp_proteas PF13975.6 CEP07671.1 - 5.2e-05 23.7 0.0 9.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP07671.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP07671.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 CEP07671.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) HAD_2 PF13419.6 CEP07671.1 - 0.058 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase End3 PF12761.7 CEP07671.1 - 0.11 12.6 0.2 2 8.5 0.0 2.5 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 RT_RNaseH PF17917.1 CEP07674.1 - 3e-09 37.1 0.0 3.4e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP07674.1 - 0.041 13.9 0.0 0.067 13.2 0.0 1.4 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase PrmC_N PF17827.1 CEP07675.1 - 0.025 15.2 0.0 11 6.8 0.0 2.7 3 0 0 3 3 3 0 PrmC N-terminal domain Rib_hydrolayse PF02267.17 CEP07675.1 - 0.092 12.1 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 ADP-ribosyl cyclase MFS_1 PF07690.16 CEP07676.1 - 1.1e-51 175.9 26.5 1.1e-51 175.9 26.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07676.1 - 2.8e-11 42.9 29.1 4.4e-11 42.3 8.8 3.1 2 1 0 3 3 3 3 Sugar (and other) transporter Steroid_dh PF02544.16 CEP07676.1 - 0.0083 16.1 1.1 0.084 12.8 0.4 2.4 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DAD PF02109.16 CEP07676.1 - 0.044 14.1 1.6 1 9.7 0.1 2.7 2 0 0 2 2 2 0 DAD family RseC_MucC PF04246.12 CEP07676.1 - 2.6 8.0 9.2 0.62 10.0 0.1 3.6 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DnaJ PF00226.31 CEP07677.1 - 2.6e-13 49.9 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Med25_SD1 PF11235.8 CEP07677.1 - 0.058 13.7 0.4 0.094 13.0 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Ribosomal_L2_C PF03947.18 CEP07679.1 - 9.4e-54 181.0 1.5 2.3e-53 179.7 1.5 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEP07679.1 - 4.1e-26 90.7 0.3 7.6e-26 89.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mg296 PF09644.10 CEP07680.1 - 0.85 9.8 4.4 0.29 11.3 0.4 2.3 3 0 0 3 3 3 0 Mg296 protein Flavi_M PF01004.19 CEP07681.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M YajC PF02699.15 CEP07681.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Mg_trans_NIPA PF05653.14 CEP07682.1 - 1.1e-21 77.3 18.2 4e-21 75.4 18.2 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEP07682.1 - 0.00024 21.3 6.4 0.00024 21.3 6.4 3.0 3 1 0 3 3 3 1 EamA-like transporter family CUE PF02845.16 CEP07683.1 - 6e-07 29.1 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 CEP07683.1 - 0.026 14.6 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 SR-25 PF10500.9 CEP07683.1 - 2.8 7.5 17.2 1.4 8.5 14.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Response_reg PF00072.24 CEP07684.1 - 3.1e-22 78.9 0.1 4.7e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain UFD1 PF03152.14 CEP07685.1 - 2.7e-46 157.2 0.0 4.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 CEP07685.1 - 1.8e-06 28.1 0.1 1.8e-06 28.1 0.1 2.6 3 0 0 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A UPF0669 PF17065.5 CEP07685.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative cytokine, C6ORF120 CDC48_2 PF02933.17 CEP07685.1 - 0.0015 18.3 0.1 0.036 13.9 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 MazE_antitoxin PF04014.18 CEP07685.1 - 0.033 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin zinc_ribbon_4 PF13717.6 CEP07685.1 - 0.041 13.8 8.3 0.054 13.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain CDC48_N PF02359.18 CEP07685.1 - 0.076 13.2 0.0 0.41 10.8 0.0 2.4 2 1 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain zf_C2H2_13 PF18508.1 CEP07685.1 - 0.73 9.5 4.5 0.29 10.8 0.5 2.4 2 0 0 2 2 2 0 Zinc finger domain zf_UBZ PF18439.1 CEP07685.1 - 7.4 6.3 10.9 0.79 9.4 0.1 3.8 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger AvrM_N PF18247.1 CEP07686.1 - 0.031 14.2 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain GCD14 PF08704.10 CEP07686.1 - 0.55 9.9 6.2 0.86 9.2 6.2 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4639 PF15479.6 CEP07686.1 - 0.63 8.9 5.8 0.81 8.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Presenilin PF01080.17 CEP07686.1 - 0.97 8.1 7.3 1.2 7.8 7.3 1.1 1 0 0 1 1 1 0 Presenilin Folate_carrier PF01770.18 CEP07686.1 - 1.5 7.5 3.6 1.9 7.1 3.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier Paramyxo_ncap PF00973.19 CEP07686.1 - 2.7 6.8 8.1 3.6 6.4 8.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Macoilin PF09726.9 CEP07686.1 - 3.2 6.2 16.4 3.8 6.0 16.4 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CEP07686.1 - 5 4.1 13.1 6.2 3.8 13.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 CEP07686.1 - 5.2 6.2 5.5 6.3 5.9 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Fungal_trans PF04082.18 CEP07688.1 - 2.7e-21 75.8 2.0 6.5e-21 74.5 2.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP07688.1 - 0.0002 21.4 1.9 0.00042 20.4 1.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4407 PF14362.6 CEP07688.1 - 2.9 7.2 5.2 5.6 6.2 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Y_phosphatase3 PF13350.6 CEP07690.1 - 4.9e-44 151.0 0.1 1.7e-43 149.2 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CEP07690.1 - 2.5e-07 30.4 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP07690.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3848 PF12959.7 CEP07691.1 - 0.0043 17.1 0.4 0.76 9.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3848) Bac_RepA_C PF18008.1 CEP07692.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain AstE_AspA PF04952.14 CEP07693.1 - 1.9e-36 125.7 0.0 2.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 CEP07693.1 - 2.1e-19 70.2 0.0 4.1e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 HutD Peptidase_M14 PF00246.24 CEP07693.1 - 0.027 14.3 0.1 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Zinc carboxypeptidase DUF3484 PF11983.8 CEP07693.1 - 1.3 10.1 4.2 32 5.7 0.0 2.7 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch SET PF00856.28 CEP07694.1 - 3.4e-08 34.0 0.2 3.4e-08 34.0 0.2 4.0 2 2 0 2 2 2 1 SET domain HSP70 PF00012.20 CEP07695.1 - 3.6e-264 877.5 13.1 4.2e-264 877.3 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP07695.1 - 2.2e-14 53.0 5.6 8.4e-13 47.8 2.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CEP07695.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CEP07695.1 - 0.00078 19.8 6.5 2.5 8.6 0.7 4.1 3 1 0 3 3 3 2 Cell division protein FtsA PIF1 PF05970.14 CEP07696.1 - 0.0025 17.0 0.0 0.0032 16.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase SNF2_N PF00176.23 CEP07697.1 - 2.9e-57 194.0 0.1 2.9e-57 194.0 0.1 2.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP07697.1 - 1.1e-17 64.3 0.0 4.3e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 CEP07697.1 - 9.9e-15 54.2 2.8 3.5e-09 36.4 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 CEP07697.1 - 2.2e-05 24.5 2.9 0.0019 18.4 0.0 4.4 4 1 0 4 4 4 1 Myb-like DNA-binding domain YfiO PF13525.6 CEP07698.1 - 0.02 14.6 0.7 1.9 8.1 0.2 2.6 2 0 0 2 2 2 0 Outer membrane lipoprotein AAA PF00004.29 CEP07700.1 - 4e-39 134.1 0.2 3.1e-37 127.9 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP07700.1 - 5e-12 45.4 0.1 1.8e-10 40.4 0.0 2.9 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 CEP07700.1 - 8.9e-05 22.5 0.2 0.0028 17.7 0.0 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP07700.1 - 0.00022 21.6 1.9 0.012 16.0 0.4 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP07700.1 - 0.00023 21.0 0.0 0.00069 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEP07700.1 - 0.00046 19.5 0.0 0.0014 17.9 0.0 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CEP07700.1 - 0.00075 19.8 4.3 0.03 14.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain TniB PF05621.11 CEP07700.1 - 0.0035 16.8 0.0 0.81 9.1 0.0 2.7 1 1 1 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 CEP07700.1 - 0.004 17.3 0.0 0.018 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEP07700.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CEP07700.1 - 0.0048 17.3 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CEP07700.1 - 0.0051 16.8 0.1 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEP07700.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CEP07700.1 - 0.0068 16.1 0.0 0.048 13.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain PUL PF08324.11 CEP07700.1 - 0.0075 15.5 0.3 0.017 14.3 0.3 1.6 1 0 0 1 1 1 1 PUL domain AAA_2 PF07724.14 CEP07700.1 - 0.013 15.6 3.6 0.014 15.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CEP07700.1 - 0.014 15.9 6.7 0.022 15.3 0.0 3.8 4 1 0 4 4 3 0 AAA domain NACHT PF05729.12 CEP07700.1 - 0.019 14.9 0.5 0.25 11.2 0.0 3.0 2 2 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CEP07700.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CEP07700.1 - 0.12 12.2 0.1 0.52 10.0 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CEP07700.1 - 0.12 11.8 0.1 0.4 10.2 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF5615 PF18480.1 CEP07700.1 - 0.13 12.1 0.1 0.51 10.1 0.0 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF5615) AAA_25 PF13481.6 CEP07700.1 - 0.14 11.7 0.4 0.75 9.3 0.1 2.4 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 CEP07700.1 - 0.14 11.4 0.4 2.5 7.4 0.1 2.4 1 1 1 2 2 2 0 KaiC Spt5_N PF11942.8 CEP07700.1 - 0.83 10.7 14.1 3.7 8.6 13.4 2.5 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ABC_tran PF00005.27 CEP07700.1 - 4.8 7.7 5.7 4.2 7.9 0.0 3.0 2 2 0 2 2 2 0 ABC transporter FAR1 PF03101.15 CEP07701.1 - 0.016 15.9 1.0 0.032 14.9 1.0 1.6 1 1 0 1 1 1 0 FAR1 DNA-binding domain Chromo PF00385.24 CEP07702.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.22 CEP07703.1 - 1.9e-41 139.7 0.0 1.1e-16 60.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP07703.1 - 9.2e-05 22.5 1.5 0.029 14.5 0.0 3.8 4 0 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CEP07703.1 - 0.00018 21.5 0.0 0.004 17.1 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CEP07703.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 2.7 2 1 0 2 2 1 1 RNA binding motif MecA PF05389.12 CEP07703.1 - 0.0022 17.7 1.1 0.08 12.6 1.0 2.1 2 0 0 2 2 2 1 Negative regulator of genetic competence (MecA) Spt20 PF12090.8 CEP07703.1 - 0.0083 15.8 24.7 0.0083 15.8 24.7 1.9 2 0 0 2 2 2 1 Spt20 family MAM33 PF02330.16 CEP07703.1 - 0.02 14.9 5.3 0.032 14.2 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein Coilin_N PF15862.5 CEP07703.1 - 0.066 13.0 5.8 0.18 11.6 5.8 1.6 1 0 0 1 1 1 0 Coilin N-terminus DUF1178 PF06676.11 CEP07703.1 - 0.11 12.9 7.8 0.2 12.1 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Reprolysin_3 PF13582.6 CEP07703.1 - 0.14 12.6 5.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like eIF-3_zeta PF05091.12 CEP07703.1 - 0.16 10.9 8.0 0.22 10.4 8.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CEP07703.1 - 0.19 11.7 9.5 0.086 12.8 7.2 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 CEP07703.1 - 0.32 10.3 5.8 0.81 9.0 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) tRNA_lig_CPD PF08302.11 CEP07703.1 - 0.32 10.4 6.8 0.56 9.6 6.8 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain CPSF100_C PF13299.6 CEP07703.1 - 0.72 10.0 6.3 0.22 11.7 3.2 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 CEP07703.1 - 1.5 9.5 19.7 0.8 10.4 14.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 CEP07703.1 - 1.9 8.2 6.5 0.45 10.3 3.1 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.14 CEP07703.1 - 4.4 7.0 5.5 8.8 6.0 5.5 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CEP07703.1 - 6.2 7.9 13.7 1.7 9.6 8.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CEP07703.1 - 7.9 5.5 10.9 12 4.8 10.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt5-NGN PF03439.13 CEP07704.1 - 6.2e-25 86.9 0.0 1.3e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CEP07704.1 - 4e-19 67.9 22.1 2.5e-06 27.2 0.1 7.0 7 0 0 7 7 7 4 KOW motif Spt5_N PF11942.8 CEP07704.1 - 2.5e-17 63.7 11.0 2.5e-17 63.7 11.0 2.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 CEP07704.1 - 6.7e-11 42.6 28.6 6.7e-11 42.6 28.6 3.6 1 1 1 2 2 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 CEP07704.1 - 0.025 14.8 0.1 0.67 10.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) PCB_OB PF17092.5 CEP07704.1 - 0.035 14.9 1.3 3.5 8.4 0.0 4.2 3 1 1 4 4 4 0 Penicillin-binding protein OB-like domain Dis3l2_C_term PF17877.1 CEP07704.1 - 0.04 14.2 2.1 2.1 8.7 0.0 3.2 1 1 0 2 2 2 0 DIS3-like exonuclease 2 C terminal YCII PF03795.14 CEP07704.1 - 0.08 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 YCII-related domain Sulfotransfer_1 PF00685.27 CEP07704.1 - 0.091 12.2 0.0 0.37 10.2 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase domain S1_2 PF13509.6 CEP07704.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 S1 domain DUF2187 PF09953.9 CEP07704.1 - 1.8 8.6 4.0 2.2 8.3 0.3 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) MBOAT PF03062.19 CEP07705.1 - 1e-50 173.1 26.2 1e-50 173.1 26.2 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HOOK PF05622.12 CEP07709.1 - 1.6e-55 188.6 75.7 6e-54 183.4 45.6 3.7 1 1 1 2 2 2 1 HOOK protein bZIP_1 PF00170.21 CEP07709.1 - 0.015 15.4 1.8 0.015 15.4 1.8 9.4 8 3 2 11 11 11 0 bZIP transcription factor HALZ PF02183.18 CEP07709.1 - 0.016 15.4 8.2 0.023 14.9 3.0 7.6 11 0 0 11 11 11 0 Homeobox associated leucine zipper CH_2 PF06294.11 CEP07709.1 - 0.024 14.8 0.1 0.18 12.0 0.1 2.6 1 0 0 1 1 1 0 CH-like domain in sperm protein MCM_N PF14551.6 CEP07709.1 - 0.3 11.7 0.1 0.3 11.7 0.1 4.4 4 1 0 4 4 4 0 MCM N-terminal domain Pox_A_type_inc PF04508.12 CEP07709.1 - 0.55 10.2 16.2 2.5 8.1 0.1 5.9 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 CEP07709.1 - 1.4 7.9 58.4 0.0085 15.2 18.9 4.8 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2344 PF10105.9 CEP07709.1 - 1.7 8.5 12.4 0.17 11.7 6.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) GAS PF13851.6 CEP07709.1 - 7.7 5.8 82.4 0.21 10.9 7.6 6.6 2 2 4 6 6 6 0 Growth-arrest specific micro-tubule binding 2-Hacid_dh_C PF02826.19 CEP07710.1 - 3.6e-60 202.4 0.0 4.8e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEP07710.1 - 2e-30 105.2 0.0 2.4e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CEP07710.1 - 4.2e-05 23.7 0.1 8.3e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CEP07710.1 - 5.5e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CEP07710.1 - 7.2e-05 22.4 0.0 0.00073 19.2 0.0 2.2 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CEP07710.1 - 0.0035 17.9 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CEP07710.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEP07710.1 - 0.035 14.6 0.0 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 CEP07710.1 - 0.11 12.8 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Bot1p PF12298.8 CEP07713.1 - 1.4e-28 100.3 0.2 2.4e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 CEP07713.1 - 1.5e-06 28.5 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 CEP07713.1 - 0.026 15.1 0.9 0.42 11.3 0.0 2.4 1 1 0 2 2 2 0 Homeodomain-like domain Phosphonate-bd PF12974.7 CEP07713.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein TIP49 PF06068.13 CEP07714.1 - 2.4e-162 540.1 1.8 3.3e-162 539.6 1.8 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEP07714.1 - 1.5e-28 98.7 0.3 3.5e-28 97.5 0.3 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CEP07714.1 - 3.3e-08 34.0 2.3 6e-05 23.5 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEP07714.1 - 6.8e-08 32.4 0.8 0.001 18.8 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CEP07714.1 - 5.7e-06 25.9 0.5 1.1e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CEP07714.1 - 6e-05 23.5 0.1 0.00022 21.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEP07714.1 - 6.3e-05 23.0 0.1 0.19 11.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEP07714.1 - 0.00069 19.1 0.9 0.05 13.0 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CEP07714.1 - 0.0013 18.8 0.2 0.96 9.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 CEP07714.1 - 0.0014 18.9 0.1 0.12 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEP07714.1 - 0.0017 18.1 0.2 3.8 7.2 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.6 CEP07714.1 - 0.0045 16.6 0.0 0.026 14.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEP07714.1 - 0.0062 16.9 5.0 0.011 16.1 2.1 2.6 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 CEP07714.1 - 0.027 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 CEP07714.1 - 0.059 13.2 0.4 0.17 11.6 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP07714.1 - 0.078 13.2 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CEP07714.1 - 0.13 11.8 0.4 0.71 9.4 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEP07714.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GPI-anchored PF10342.9 CEP07715.1 - 5.1e-10 40.0 0.8 5.1e-10 40.0 0.8 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family C2 PF00168.30 CEP07717.1 - 3.3e-24 85.1 0.1 4.1e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 C2 domain HTH_29 PF13551.6 CEP07718.1 - 1.4e-05 25.0 0.0 5.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_psq PF05225.16 CEP07718.1 - 8.8e-05 22.2 0.0 0.00028 20.6 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 CEP07718.1 - 0.00011 21.8 0.0 0.00053 19.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 CEP07718.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP07718.1 - 0.00079 19.5 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 CEP07718.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.19 CEP07718.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 CEP07718.1 - 0.028 14.2 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.6 CEP07718.1 - 0.029 14.1 0.2 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 CEP07718.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 CEP07718.1 - 0.062 13.2 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family UPF0175 PF03683.13 CEP07718.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_3 PF01381.22 CEP07718.1 - 0.12 12.5 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix HTH_1 PF00126.27 CEP07718.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family RPA_C PF08784.11 CEP07718.1 - 0.95 10.2 3.7 22 5.8 0.5 2.8 3 0 0 3 3 3 0 Replication protein A C terminal MAM33 PF02330.16 CEP07719.1 - 3.6e-73 246.0 5.5 4.2e-73 245.8 5.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3337 PF11816.8 CEP07720.1 - 9.8e-42 142.7 0.0 5.3e-41 140.3 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CEP07720.1 - 1.2e-21 76.6 15.4 1.9e-06 28.5 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07720.1 - 3.2e-06 27.4 0.0 0.1 12.9 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP07720.1 - 0.00052 19.1 0.0 0.012 14.6 0.0 2.5 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEP07720.1 - 0.004 16.5 0.0 0.11 11.8 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain RAWUL PF16207.5 CEP07720.1 - 0.06 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF1151 PF06625.11 CEP07721.1 - 0.7 9.9 8.5 0.3 11.0 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) CDC45 PF02724.14 CEP07721.1 - 0.88 7.8 8.6 1.3 7.2 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S9_N PF02897.15 CEP07722.1 - 4.6e-60 203.6 5.7 6.2e-60 203.1 5.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CEP07722.1 - 3.5e-52 177.0 0.0 6.5e-52 176.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CEP07722.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP07722.1 - 0.0058 16.3 0.1 0.05 13.3 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 CEP07722.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AMP-binding PF00501.28 CEP07723.1 - 2e-41 142.0 0.0 4.8e-30 104.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AAA_16 PF13191.6 CEP07724.1 - 2.4e-08 34.6 0.0 3.7e-07 30.7 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain Guanylate_cyc PF00211.20 CEP07724.1 - 0.0038 16.9 0.1 0.62 9.7 0.0 3.2 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain AAA_18 PF13238.6 CEP07724.1 - 0.005 17.4 0.1 0.032 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CEP07724.1 - 0.0064 16.4 0.1 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CEP07724.1 - 0.0091 16.4 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CEP07724.1 - 0.016 15.5 0.2 0.26 11.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CEP07724.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PPV_E1_C PF00519.17 CEP07724.1 - 0.028 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase T2SSE PF00437.20 CEP07724.1 - 0.078 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CEP07724.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 CEP07724.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C12 PF01088.21 CEP07725.1 - 6.5e-48 163.3 0.0 9.9e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NDC10_II PF16787.5 CEP07726.1 - 7.7e-42 143.5 0.3 1.5e-38 132.7 0.3 2.4 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP07726.1 - 5.5e-19 68.3 3.4 2e-18 66.5 3.4 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.11 CEP07726.1 - 0.0096 16.1 2.4 0.018 15.2 0.9 2.3 2 0 0 2 2 2 1 QacR-like protein, C-terminal region Phage_integrase PF00589.22 CEP07726.1 - 0.03 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family Flavi_capsid PF01003.19 CEP07726.1 - 0.27 11.0 1.3 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 Flavivirus capsid protein C Glyco_hydro_3_C PF01915.22 CEP07729.1 - 4e-22 79.2 0.0 5.8e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CEP07729.1 - 6.7e-05 22.9 0.0 0.00068 19.7 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 CEP07730.1 - 1.8e-57 194.6 0.1 3.6e-57 193.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEP07730.1 - 1.1e-38 133.4 0.0 1.8e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEP07730.1 - 2e-21 75.8 0.0 3.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RVT_1 PF00078.27 CEP07731.1 - 0.043 13.3 0.1 0.043 13.3 0.1 2.8 3 1 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4746 PF15928.5 CEP07731.1 - 0.047 13.1 2.8 0.24 10.8 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4746) Bac_DNA_binding PF00216.21 CEP07731.1 - 0.063 13.5 8.9 0.84 9.9 0.2 4.0 4 1 1 5 5 5 0 Bacterial DNA-binding protein PDEase_I_N PF08499.12 CEP07731.1 - 0.092 12.6 0.3 0.47 10.3 0.1 2.3 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PASTA PF03793.19 CEP07731.1 - 0.59 10.0 0.1 0.59 10.0 0.1 3.4 5 0 0 5 5 5 0 PASTA domain YtxH PF12732.7 CEP07731.1 - 0.77 10.3 0.1 0.77 10.3 0.1 6.3 3 2 1 4 4 4 0 YtxH-like protein Phage_int_SAM_5 PF13102.6 CEP07731.1 - 0.9 9.9 4.6 3 8.2 0.1 3.3 3 1 1 4 4 4 0 Phage integrase SAM-like domain TrbC PF04956.13 CEP07731.1 - 1.3 9.3 4.9 0.78 10.0 0.1 2.8 2 0 0 2 2 2 0 TrbC/VIRB2 family FERM_F2 PF18377.1 CEP07731.1 - 2.3 8.2 5.7 1.2 9.1 0.3 2.9 3 1 1 4 4 4 0 FERM F2 acyl-CoA binding protein-like domain Cob_adeno_trans PF01923.18 CEP07731.1 - 7.1 6.7 12.3 0.89 9.7 1.5 3.6 3 2 1 4 4 4 0 Cobalamin adenosyltransferase Mnd1 PF03962.15 CEP07731.1 - 7.9 6.9 6.6 1.6 9.1 0.3 3.1 4 0 0 4 4 4 0 Mnd1 HTH domain FA_desaturase PF00487.24 CEP07732.1 - 6e-17 62.3 17.7 8.9e-17 61.8 17.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEP07732.1 - 5.2e-11 42.5 0.1 1.2e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MerC PF03203.14 CEP07732.1 - 0.016 15.7 0.2 0.016 15.7 0.2 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein WD40 PF00400.32 CEP07734.1 - 2.9e-24 84.9 5.5 4.4e-07 30.5 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07734.1 - 6.4e-06 26.4 0.1 2.5 8.5 0.0 4.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP07734.1 - 7.4e-06 25.5 2.4 1.4e-05 24.6 1.7 1.7 1 1 1 2 2 2 1 WD40-like domain SUKH_6 PF14568.6 CEP07734.1 - 0.13 12.7 0.2 1.9 8.9 0.1 2.1 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall zf-CCCH PF00642.24 CEP07735.1 - 2e-18 65.8 12.9 2.6e-09 36.7 4.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP07735.1 - 3.3e-12 46.0 16.4 1.2e-06 28.3 7.1 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEP07735.1 - 6.5e-11 41.8 14.5 2.3e-05 24.1 5.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEP07735.1 - 0.0026 18.2 2.3 0.0026 18.2 2.3 2.9 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEP07735.1 - 0.009 16.7 10.7 0.29 11.8 0.7 2.5 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 CEP07735.1 - 0.043 14.3 2.2 3.4 8.2 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Amidohydro_1 PF01979.20 CEP07736.1 - 1.2e-23 84.0 0.0 2.9e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP07736.1 - 1.2e-10 41.5 0.3 3.5e-07 30.1 0.0 2.9 4 0 0 4 4 4 2 Amidohydrolase family Tudor_FRX1 PF18336.1 CEP07736.1 - 0.18 11.7 0.1 0.67 9.9 0.1 1.9 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain TFIIA PF03153.13 CEP07737.1 - 0.00071 19.7 17.0 0.00088 19.4 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CEP07737.1 - 0.0078 15.0 7.2 0.0084 14.8 7.2 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Virul_Fac PF10139.9 CEP07737.1 - 0.038 12.2 9.6 0.05 11.8 9.6 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor V_ATPase_I PF01496.19 CEP07737.1 - 0.078 10.9 8.8 0.12 10.3 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NifQ PF04891.12 CEP07737.1 - 0.94 9.8 12.0 0.065 13.6 6.6 1.8 2 0 0 2 2 2 0 NifQ Suf PF05843.14 CEP07737.1 - 7.4 6.5 14.6 10 6.0 14.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MFS_1 PF07690.16 CEP07738.1 - 3.6e-12 45.9 41.1 3.6e-12 45.9 41.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CEP07738.1 - 6.4e-12 45.5 8.5 6.4e-12 45.5 8.5 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF3894 PF13033.6 CEP07738.1 - 1.3 9.2 10.1 0.19 11.9 1.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3894) Peptidase_M13 PF01431.21 CEP07739.1 - 2.2e-55 187.5 0.3 4.5e-55 186.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CEP07739.1 - 1.5e-38 133.5 0.2 3e-38 132.5 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 CEP07739.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M48 Sec16_C PF12931.7 CEP07740.1 - 1.2e-87 294.4 0.1 1.2e-87 294.4 0.1 1.8 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CEP07740.1 - 4.8e-26 91.7 2.0 6.6e-26 91.2 0.0 2.3 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.7 CEP07740.1 - 0.0029 17.6 1.1 0.0064 16.5 1.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CEP07740.1 - 0.051 13.3 2.7 0.099 12.4 2.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain CCDC32 PF14989.6 CEP07741.1 - 1.4 8.9 7.2 4 7.4 7.2 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing 32 Mucin PF01456.17 CEP07741.1 - 7.3 6.6 15.3 8.6 6.3 15.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CCDC32 PF14989.6 CEP07742.1 - 1.4 8.9 7.2 4 7.4 7.2 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing 32 Mucin PF01456.17 CEP07742.1 - 7.3 6.6 15.3 8.6 6.3 15.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Adaptin_N PF01602.20 CEP07743.1 - 1.9e-143 478.8 8.0 2.5e-143 478.4 8.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEP07743.1 - 1.4e-21 77.2 7.6 4.3e-20 72.4 0.0 4.0 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP07743.1 - 8.8e-11 42.0 2.5 0.0018 18.6 0.2 4.6 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CEP07743.1 - 0.00027 20.9 12.4 0.2 12.0 0.0 7.3 9 0 0 9 9 9 1 HEAT repeat Cohesin_HEAT PF12765.7 CEP07743.1 - 0.011 16.0 0.0 0.041 14.2 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CEP07743.1 - 0.012 16.1 2.3 10 6.7 0.4 4.6 4 0 0 4 4 4 0 HEAT-like repeat adh_short_C2 PF13561.6 CEP07743.1 - 0.19 11.2 0.0 0.49 9.9 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Arm PF00514.23 CEP07743.1 - 0.35 11.0 5.3 2.1 8.5 0.5 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SDA1 PF05285.12 CEP07743.1 - 0.7 9.3 19.8 1.8 7.9 19.8 1.7 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CEP07743.1 - 3.8 5.6 22.4 7.2 4.7 22.4 1.4 1 0 0 1 1 1 0 Nop14-like family PH PF00169.29 CEP07744.1 - 6.5e-11 42.7 0.2 3.4e-09 37.2 0.0 3.4 2 1 0 2 2 2 1 PH domain PH_6 PF15406.6 CEP07744.1 - 0.063 13.6 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain TIG_2 PF18020.1 CEP07744.1 - 0.15 12.7 0.6 2.1 9.0 0.1 2.6 2 0 0 2 2 2 0 TIG domain found in plexin Aldedh PF00171.22 CEP07746.1 - 3e-165 550.2 1.2 7.9e-148 492.8 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP07746.1 - 0.00023 20.7 0.1 0.24 10.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 CEP07746.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ank_5 PF13857.6 CEP07747.1 - 8.3e-36 121.6 1.6 2.5e-10 40.4 0.0 6.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP07747.1 - 1.2e-32 112.3 0.8 1.6e-11 44.6 0.0 5.7 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP07747.1 - 6.5e-29 99.9 4.3 4e-06 27.3 0.0 7.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP07747.1 - 8.1e-22 75.0 3.0 0.0019 18.5 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 CEP07747.1 - 2.4e-21 75.2 16.5 0.00019 21.7 0.0 7.8 7 2 0 7 7 7 4 Ankyrin repeat T7SS_ESX_EspC PF10824.8 CEP07747.1 - 0.56 10.7 0.0 0.56 10.7 0.0 3.5 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm RCSD PF05177.12 CEP07747.1 - 2.8 8.9 5.2 7.8 7.5 5.2 1.7 1 0 0 1 1 1 0 RCSD region AIG1 PF04548.16 CEP07748.1 - 3.9e-18 65.6 0.2 9.2e-18 64.3 0.2 1.6 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 CEP07748.1 - 2.5e-08 33.5 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP07748.1 - 1.8e-07 31.2 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEP07748.1 - 2.5e-06 27.6 0.6 0.0073 16.4 0.2 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 CEP07748.1 - 0.0073 16.2 2.1 0.029 14.3 0.8 2.4 2 1 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 CEP07748.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 CEP07748.1 - 0.13 12.4 0.2 0.42 10.9 0.2 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Roughex PF06020.11 CEP07749.1 - 0.00093 18.4 3.0 0.0012 18.0 3.0 1.1 1 0 0 1 1 1 1 Drosophila roughex protein SWI-SNF_Ssr4 PF08549.10 CEP07749.1 - 0.022 13.4 4.2 0.025 13.2 4.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) V_ATPase_I PF01496.19 CEP07749.1 - 1.1 7.1 5.1 1.3 6.8 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 CEP07749.1 - 1.7 7.1 15.4 2.1 6.8 15.4 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CEP07749.1 - 9.6 4.8 8.2 11 4.7 8.2 1.2 1 0 0 1 1 1 0 Presenilin HSF_DNA-bind PF00447.17 CEP07750.1 - 2.1e-25 89.1 0.3 8.3e-25 87.2 0.3 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Zn_clus PF00172.18 CEP07750.1 - 1.5e-08 34.6 12.5 2.8e-08 33.7 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThrE PF06738.12 CEP07751.1 - 2.7e-47 161.2 18.5 3.2e-45 154.4 5.4 3.0 2 1 1 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 CEP07751.1 - 8.3e-08 32.4 29.8 0.00011 22.3 7.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF572 PF04502.13 CEP07752.1 - 1.3e-75 255.1 14.6 2.2e-75 254.4 13.0 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 CEP07752.1 - 0.042 13.9 2.8 1.4 9.1 0.5 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DNA_RNApol_7kD PF03604.13 CEP07752.1 - 0.13 12.0 0.8 18 5.1 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 CEP07752.1 - 0.14 12.2 1.1 0.67 10.0 0.3 2.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA E6 PF00518.17 CEP07752.1 - 0.15 12.5 0.3 7 7.1 0.1 2.4 1 1 1 2 2 2 0 Early Protein (E6) zinc_ribbon_4 PF13717.6 CEP07752.1 - 0.18 11.8 1.0 5.7 7.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Mut7-C PF01927.16 CEP07752.1 - 0.2 11.8 3.8 29 4.7 0.4 2.8 2 1 1 3 3 3 0 Mut7-C RNAse domain TF_Zn_Ribbon PF08271.12 CEP07752.1 - 0.36 10.4 2.4 3.7 7.1 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3449 PF11931.8 CEP07752.1 - 0.63 9.8 4.4 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-NADH-PPase PF09297.11 CEP07752.1 - 0.8 9.4 2.8 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CpXC PF14353.6 CEP07752.1 - 0.81 9.7 3.9 8.7 6.4 0.1 2.8 2 1 1 3 3 3 0 CpXC protein MFS_1 PF07690.16 CEP07753.1 - 1.1e-17 64.1 17.1 1.2e-17 63.9 6.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 CEP07753.1 - 1.4 9.1 5.5 5.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Arrestin_N PF00339.29 CEP07754.1 - 1.6e-06 28.2 0.5 0.013 15.5 0.0 3.8 3 0 0 3 3 3 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP07754.1 - 5.7e-05 23.6 9.0 0.0058 17.1 0.7 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DUF748 PF05359.11 CEP07754.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) MFS_1 PF07690.16 CEP07755.1 - 1.5e-45 155.6 34.1 1.5e-45 155.6 34.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP07755.1 - 3.6e-17 62.4 18.2 3.6e-17 62.4 18.2 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEP07755.1 - 6.4e-06 24.9 4.8 6.4e-06 24.9 4.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Wzz PF02706.15 CEP07755.1 - 0.021 15.1 4.3 0.16 12.3 0.0 3.4 3 0 0 3 3 3 0 Chain length determinant protein DUF5381 PF17353.2 CEP07755.1 - 1.5 8.5 3.7 4.4 7.0 3.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Ribosomal_S8 PF00410.19 CEP07756.1 - 3.7e-24 85.1 0.0 4.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Amidohydro_2 PF04909.14 CEP07757.1 - 9.6e-29 101.1 0.0 1.4e-28 100.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Sec20 PF03908.13 CEP07758.1 - 0.0017 18.2 1.9 0.002 18.0 1.9 1.2 1 0 0 1 1 1 1 Sec20 SMK-1 PF04802.15 CEP07758.1 - 0.014 15.2 0.5 0.016 15.1 0.5 1.1 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 DivIC PF04977.15 CEP07758.1 - 0.02 14.7 1.3 0.026 14.3 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.9 CEP07758.1 - 0.055 13.8 3.2 0.081 13.2 3.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4088 PF13317.6 CEP07758.1 - 0.074 12.6 0.2 0.082 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) PCRF PF03462.18 CEP07758.1 - 0.084 12.7 1.7 0.097 12.5 1.7 1.0 1 0 0 1 1 1 0 PCRF domain TMF_DNA_bd PF12329.8 CEP07758.1 - 0.099 12.7 5.3 0.064 13.3 2.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FTHFS PF01268.19 CEP07759.1 - 8.5e-265 879.2 0.0 1.2e-264 878.7 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CEP07759.1 - 1.4e-66 222.7 2.8 1.4e-66 222.7 2.8 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CEP07759.1 - 2.9e-40 137.2 2.4 4.7e-39 133.3 2.0 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 CEP07759.1 - 0.059 12.3 1.3 0.1 11.5 1.3 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 CEP07759.1 - 0.063 13.3 2.6 4.1 7.4 2.6 2.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rad9 PF04139.13 CEP07760.1 - 2.5e-34 118.8 0.1 3.3e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CEP07760.1 - 0.035 13.2 0.1 0.061 12.4 0.1 1.4 1 0 0 1 1 1 0 Hus1-like protein Ricin_B_lectin PF00652.22 CEP07761.1 - 0.00028 21.2 0.1 0.00069 19.9 0.1 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEP07761.1 - 0.00059 20.5 0.7 0.034 14.9 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Hexokinase_2 PF03727.16 CEP07762.1 - 1.3e-67 227.8 0.1 1.9e-67 227.2 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP07762.1 - 1.1e-45 156.0 0.0 1.6e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cullin PF00888.22 CEP07763.1 - 1.2e-137 460.2 6.0 1.5e-137 459.8 6.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEP07763.1 - 6.7e-25 86.9 6.4 2.3e-24 85.2 4.4 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4070 PF13282.6 CEP07763.1 - 0.00093 19.3 0.1 0.0037 17.4 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) NCD2 PF04905.13 CEP07764.1 - 7.3e-07 29.2 0.0 7.3e-07 29.2 0.0 2.9 3 1 0 3 3 3 1 NAB conserved region 2 (NCD2) NCD1 PF04904.13 CEP07764.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Draxin PF15550.6 CEP07764.1 - 0.085 12.7 11.8 0.14 12.0 11.8 1.3 1 0 0 1 1 1 0 Draxin SAM_2 PF07647.17 CEP07764.1 - 0.1 12.7 0.2 0.67 10.1 0.2 2.3 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) DUF4200 PF13863.6 CEP07764.1 - 1.5 9.2 20.7 0.097 13.1 9.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) rRNA_processing PF08524.11 CEP07764.1 - 1.7 8.7 20.2 0.2 11.7 11.9 2.3 2 0 0 2 2 2 0 rRNA processing DUF5473 PF17567.2 CEP07765.1 - 0.079 13.3 14.5 1.7 9.0 2.1 3.3 2 1 0 2 2 2 0 Family of unknown function (DUF5473) WSK PF03832.13 CEP07765.1 - 0.11 12.2 0.3 0.11 12.2 0.3 3.7 4 0 0 4 4 4 0 WSK motif NAD_binding_2 PF03446.15 CEP07766.1 - 9.6e-34 116.8 0.0 2e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEP07766.1 - 1.1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CEP07766.1 - 8.8e-08 32.6 0.1 1.5e-06 28.7 0.0 2.4 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CEP07766.1 - 3.2e-06 27.2 0.0 7.9e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 CEP07766.1 - 0.034 14.1 0.3 0.19 11.7 0.2 2.3 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPOR PF05036.13 CEP07766.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Sporulation related domain Catalase PF00199.19 CEP07767.1 - 1e-159 531.8 0.4 1.5e-159 531.2 0.4 1.3 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 CEP07767.1 - 3.3e-34 117.7 0.0 5.1e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 CEP07767.1 - 5.3e-18 65.0 0.1 1.1e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 CEP07767.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Phage_lysis PF03245.13 CEP07768.1 - 0.002 18.3 15.9 0.0072 16.4 15.9 2.0 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein DUF1192 PF06698.11 CEP07768.1 - 0.24 11.5 5.4 12 6.0 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) AIG1 PF04548.16 CEP07769.1 - 3.9e-16 59.0 0.0 6.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 CEP07769.1 - 4.6e-08 33.1 0.0 7.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP07769.1 - 3.5e-05 23.8 0.0 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CEP07769.1 - 9.7e-05 22.5 0.2 0.19 11.8 0.1 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 CEP07769.1 - 0.00011 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 CEP07769.1 - 0.0088 16.6 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Spatacsin_C PF14649.6 CEP07769.1 - 0.067 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus EpCAM_N PF18635.1 CEP07769.1 - 0.22 11.7 0.8 0.53 10.5 0.8 1.6 1 0 0 1 1 1 0 Epithelial cell adhesion molecule N-terminal domain FR47 PF08445.10 CEP07771.1 - 0.0031 17.4 0.1 0.033 14.2 0.1 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 CEP07771.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PAP2 PF01569.21 CEP07772.1 - 2.6e-19 69.4 3.2 7.7e-19 67.8 3.2 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CEP07772.1 - 0.029 14.1 12.0 0.014 15.1 8.1 2.6 2 1 0 2 2 2 0 PAP2 superfamily Ribosomal_S11 PF00411.19 CEP07773.1 - 2.8e-47 159.7 1.0 3.5e-47 159.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CEP07773.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Anp1 PF03452.14 CEP07774.1 - 1.5e-85 286.9 0.0 1.7e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CEP07774.1 - 4.2e-06 26.7 0.0 0.00012 21.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Pex16 PF08610.10 CEP07775.1 - 1.5e-103 346.4 3.8 1.7e-103 346.2 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Choline_kinase PF01633.20 CEP07775.1 - 0.089 12.4 0.3 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase PRELI PF04707.14 CEP07776.1 - 3.4e-47 160.2 0.2 4.1e-47 159.9 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Peptidase_C80 PF11713.8 CEP07776.1 - 0.091 13.0 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase C80 family Methyltransf_25 PF13649.6 CEP07777.1 - 2.3e-16 60.3 0.0 4.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP07777.1 - 1.9e-13 50.8 0.0 3.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP07777.1 - 2.2e-11 43.8 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP07777.1 - 1.9e-10 40.8 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP07777.1 - 4.9e-08 32.6 0.0 6.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CEP07777.1 - 5.6e-08 32.4 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CEP07777.1 - 3.4e-07 30.9 0.0 5.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEP07777.1 - 1.6e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 CEP07777.1 - 0.00093 19.4 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.11 CEP07777.1 - 0.0038 16.9 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 CEP07777.1 - 0.031 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Pox_MCEL PF03291.16 CEP07777.1 - 0.092 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MTS PF05175.14 CEP07777.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Pkinase PF00069.25 CEP07778.1 - 1.3e-60 205.0 0.0 6.4e-39 133.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07778.1 - 1.5e-29 103.1 0.0 2.8e-22 79.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP07778.1 - 0.00039 19.8 0.0 0.011 15.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CEP07778.1 - 0.0056 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS PF00989.25 CEP07778.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.3 3 0 0 3 3 3 0 PAS fold Haspin_kinase PF12330.8 CEP07778.1 - 0.015 14.3 0.0 0.015 14.3 0.0 3.2 4 0 0 4 4 4 0 Haspin like kinase domain PAS_9 PF13426.7 CEP07778.1 - 0.04 14.2 0.2 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain Seadorna_VP7 PF07387.11 CEP07778.1 - 0.055 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ifi-6-16 PF06140.13 CEP07779.1 - 2.8e-14 52.8 14.4 4.6e-14 52.1 14.4 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF3482 PF11981.8 CEP07779.1 - 0.79 9.1 3.1 1.2 8.4 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) MFS18 PF17352.2 CEP07779.1 - 9.5 6.7 8.3 19 5.7 8.3 1.5 1 1 0 1 1 1 0 Male Flower Specific protein 18 GRIP PF01465.20 CEP07780.1 - 6.1e-17 61.3 0.2 2.2e-16 59.5 0.2 2.1 1 0 0 1 1 1 1 GRIP domain Fez1 PF06818.15 CEP07780.1 - 0.0042 17.6 27.5 0.0042 17.6 27.5 8.3 1 1 6 8 8 8 2 Fez1 PXA PF02194.15 CEP07781.1 - 3.2e-27 95.7 0.5 3.2e-27 95.7 0.5 3.1 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CEP07781.1 - 1.2e-08 35.5 0.4 8.4e-08 32.8 0.0 2.5 2 1 0 2 2 2 1 Sorting nexin C terminal Mucin PF01456.17 CEP07781.1 - 0.31 11.0 19.7 0.5 10.4 19.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HTH_32 PF13565.6 CEP07782.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.6 CEP07782.1 - 0.035 13.9 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease KaiA PF07688.12 CEP07782.1 - 0.038 14.1 0.6 0.093 12.9 0.1 1.8 2 0 0 2 2 2 0 KaiA C-terminal domain HTH_AsnC-type PF13404.6 CEP07782.1 - 0.046 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Stork_head PF10264.9 CEP07782.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Transposase_24 PF03004.14 CEP07782.1 - 0.071 13.2 0.5 0.13 12.4 0.5 1.4 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) HTH_24 PF13412.6 CEP07782.1 - 0.12 12.0 0.1 0.57 9.8 0.0 2.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PTPlike_phytase PF14566.6 CEP07782.1 - 0.28 11.3 4.4 6.3 6.9 0.1 2.2 1 1 0 2 2 2 0 Inositol hexakisphosphate VASt PF16016.5 CEP07785.1 - 7e-30 104.5 1.0 3.4e-29 102.2 0.0 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CEP07785.1 - 3e-12 46.8 2.2 6.4e-12 45.7 2.2 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CEP07785.1 - 7e-10 39.4 1.1 1.6e-09 38.2 0.2 2.2 2 0 0 2 2 2 1 PH domain RepB-RCR_reg PF10723.9 CEP07785.1 - 0.045 13.7 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Replication regulatory protein RepB Lyase_1 PF00206.20 CEP07786.1 - 3.8e-118 394.4 0.0 8.3e-118 393.3 0.0 1.5 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.9 CEP07786.1 - 9e-23 80.5 0.0 1.8e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus SBP_bac_3 PF00497.20 CEP07786.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF1992 PF09350.10 CEP07787.1 - 0.052 13.7 0.1 18 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1992) HMG_box_5 PF14887.6 CEP07787.1 - 0.12 12.3 0.1 0.81 9.7 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 OrfB_Zn_ribbon PF07282.11 CEP07788.1 - 0.00011 22.1 0.1 0.00022 21.1 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Pkinase PF00069.25 CEP07789.1 - 2e-74 250.3 0.0 2.3e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07789.1 - 1.2e-30 106.7 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP07789.1 - 0.005 16.2 0.0 0.0084 15.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CEP07789.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CEP07789.1 - 0.019 14.9 0.4 0.029 14.3 0.4 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CEP07790.1 - 0.0083 17.0 0.1 0.15 12.9 0.1 2.7 1 1 1 2 2 2 1 WD domain, G-beta repeat adh_short_C2 PF13561.6 CEP07791.1 - 3.6e-48 164.2 0.1 4.9e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP07791.1 - 2.9e-47 160.7 0.1 4.4e-47 160.1 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CEP07791.1 - 1.9e-09 37.7 0.1 3.8e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CEP07791.1 - 0.0065 16.0 0.1 0.017 14.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PTPA PF03095.15 CEP07792.1 - 0.00084 18.9 0.4 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2795 PF11387.8 CEP07792.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Peptidase_C80 PF11713.8 CEP07792.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family DUF2520 PF10728.9 CEP07793.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Asp PF00026.23 CEP07795.1 - 3e-67 227.3 1.0 3.6e-67 227.0 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP07795.1 - 3.1e-15 56.9 3.2 3.6e-09 37.1 0.1 3.6 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP07795.1 - 0.00017 21.4 0.2 0.0017 18.2 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DeoRC PF00455.22 CEP07795.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 DeoR C terminal sensor domain Asp_protease_2 PF13650.6 CEP07795.1 - 0.033 14.8 0.2 1.2 9.8 0.1 3.1 3 1 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 CEP07795.1 - 0.1 13.2 0.0 9.6 6.9 0.0 3.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 CEP07796.1 - 2.4e-14 53.5 0.3 5.1e-11 42.6 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Glucodextran_C PF09985.9 CEP07796.1 - 0.081 12.4 0.1 5.6 6.3 0.0 2.4 2 1 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase RIBIOP_C PF04950.12 CEP07797.1 - 6.1e-93 311.4 0.1 6.1e-93 311.4 0.1 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CEP07797.1 - 3.8e-32 110.2 0.0 2e-31 107.9 0.0 2.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CEP07797.1 - 3.5e-06 26.7 0.0 0.0009 18.8 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CEP07797.1 - 3.9e-06 27.2 0.0 1.5e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP07797.1 - 0.00013 22.4 0.0 0.00034 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CEP07797.1 - 0.00017 21.8 0.8 0.00046 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CEP07797.1 - 0.0002 21.4 0.8 0.0031 17.6 0.2 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 CEP07797.1 - 0.00023 21.6 0.0 0.00069 20.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CEP07797.1 - 0.0024 17.6 0.0 0.0071 16.1 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 CEP07797.1 - 0.0029 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP07797.1 - 0.0032 18.0 0.0 0.0032 18.0 0.0 3.2 4 1 0 4 4 1 1 AAA domain RNA_helicase PF00910.22 CEP07797.1 - 0.0042 17.5 0.0 0.018 15.4 0.0 2.1 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 CEP07797.1 - 0.0073 16.8 0.0 0.0073 16.8 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 CEP07797.1 - 0.0096 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 CEP07797.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 CEP07797.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEP07797.1 - 0.044 13.8 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 CEP07797.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CEP07797.1 - 0.056 13.4 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CEP07797.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CEP07797.1 - 0.087 12.6 0.1 0.087 12.6 0.1 4.2 3 2 1 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 CEP07797.1 - 0.11 12.4 0.1 0.64 9.9 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 CEP07797.1 - 0.22 11.3 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Peroxin-22 PF12827.7 CEP07798.1 - 0.017 15.0 0.7 0.037 13.9 0.8 1.5 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family DUF3216 PF11505.8 CEP07798.1 - 0.079 13.2 0.1 0.62 10.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3216) GRA6 PF05084.13 CEP07798.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Asp PF00026.23 CEP07799.1 - 1.2e-56 192.4 0.3 2.3e-56 191.5 0.3 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP07799.1 - 2.2e-14 54.1 2.1 2.6e-07 31.0 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 CEP07800.1 - 6.7e-72 242.6 5.4 4.7e-70 236.5 5.4 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP07800.1 - 5.8e-14 52.7 2.1 1.2e-12 48.4 1.7 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEP07800.1 - 0.0034 18.0 0.9 5.2 7.8 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 CEP07800.1 - 0.0034 17.2 0.0 0.1 12.4 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 CEP07800.1 - 0.033 14.8 1.2 0.72 10.5 0.0 3.2 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Adenylsucc_synt PF00709.21 CEP07801.1 - 8.5e-181 601.4 0.0 9.5e-181 601.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Sugar_tr PF00083.24 CEP07802.1 - 1.7e-131 439.2 28.7 2.2e-131 438.8 28.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP07802.1 - 5.7e-34 117.6 62.3 2.6e-26 92.4 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CEP07802.1 - 0.0015 16.9 1.5 0.0015 16.9 1.5 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 CEP07803.1 - 2e-70 237.1 0.0 3.1e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP07803.1 - 5.1e-35 121.0 0.0 1e-34 120.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP07803.1 - 0.00076 18.9 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP07803.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_N PF00339.29 CEP07804.1 - 7.8e-12 45.5 0.2 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP07804.1 - 1.1e-05 25.9 0.0 4.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain HEPN_AbiU2 PF18734.1 CEP07805.1 - 0.038 13.5 0.2 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 AbiU2 GPHH PF16905.5 CEP07805.1 - 0.1 12.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DDRGK PF09756.9 CEP07806.1 - 1.5e-13 50.8 28.8 1.5e-13 50.8 28.8 1.8 2 0 0 2 2 2 1 DDRGK domain HTH_26 PF13443.6 CEP07806.1 - 0.01 16.2 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Homez PF11569.8 CEP07806.1 - 0.081 12.4 0.6 0.42 10.1 0.0 2.3 1 1 1 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Put_Phosphatase PF06888.12 CEP07806.1 - 0.084 12.3 2.0 0.52 9.7 0.1 2.1 1 1 1 2 2 2 0 Putative Phosphatase Folate_carrier PF01770.18 CEP07806.1 - 2 7.1 5.2 4.7 5.8 4.0 1.8 2 0 0 2 2 2 0 Reduced folate carrier MMR1 PF08505.10 CEP07806.1 - 2.6 8.3 15.8 3.4 7.9 15.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FapA PF03961.13 CEP07806.1 - 3.4 6.1 14.6 4.6 5.7 14.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CEP07806.1 - 6.1 4.6 16.4 3.7 5.4 0.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Ank_3 PF13606.6 CEP07807.1 - 1.2e-11 43.7 0.0 0.0042 17.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 CEP07807.1 - 1.6e-10 41.4 0.0 5.3e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEP07807.1 - 2.6e-07 30.8 0.0 0.0071 16.8 0.1 3.8 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP07807.1 - 8.1e-06 26.0 0.1 0.0038 17.5 0.0 3.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP07807.1 - 0.00014 22.4 0.0 0.0048 17.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Isochorismatase PF00857.20 CEP07808.1 - 1.2e-27 97.2 0.1 1.5e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1481 PF07356.12 CEP07808.1 - 0.0052 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1481) SCP2 PF02036.17 CEP07809.1 - 2e-09 37.8 0.1 2.8e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Ysc84 PF04366.12 CEP07810.1 - 1.7e-41 141.0 0.1 3e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CEP07810.1 - 2e-14 52.9 0.0 4.9e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP07810.1 - 1.2e-12 47.3 0.0 2.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP07810.1 - 3.2e-11 42.9 0.0 6.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ACOX PF01756.19 CEP07812.1 - 1.6e-50 171.2 0.0 3e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEP07812.1 - 1.1e-25 90.6 2.4 2.6e-25 89.4 2.4 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEP07812.1 - 2.6e-13 50.0 0.0 5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP07812.1 - 2.4e-05 24.6 0.1 0.00023 21.4 0.0 2.5 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Z1 PF10593.9 CEP07812.1 - 0.17 11.4 0.1 0.17 11.4 0.1 1.8 2 0 0 2 2 2 0 Z1 domain RHD3 PF05879.12 CEP07813.1 - 1.1e-252 840.5 20.4 2.4e-249 829.4 20.4 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 CEP07813.1 - 4.8e-06 26.6 0.1 1.5e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEP07813.1 - 7.5e-06 26.1 1.7 1e-05 25.6 0.0 2.1 2 1 0 2 2 2 1 Dynamin family GBP PF02263.19 CEP07813.1 - 1.6e-05 24.3 0.2 4.8e-05 22.8 0.2 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Septin PF00735.18 CEP07813.1 - 0.019 14.3 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 CEP07813.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ELM2 PF01448.24 CEP07813.1 - 0.036 14.8 0.3 3.3 8.5 0.2 2.9 2 0 0 2 2 2 0 ELM2 domain RsgA_GTPase PF03193.16 CEP07813.1 - 0.054 13.4 0.3 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase RmlD_sub_bind PF04321.17 CEP07814.1 - 1.4e-57 195.0 0.0 3.7e-56 190.3 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CEP07814.1 - 9.8e-25 87.4 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEP07814.1 - 2.9e-08 33.5 0.0 2.4e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CEP07814.1 - 4.4e-07 29.3 0.1 1.5e-05 24.3 0.0 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CEP07814.1 - 3.3e-06 26.5 0.0 4.3e-05 22.8 0.0 2.5 1 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CEP07814.1 - 2.1e-05 23.7 0.0 8.2e-05 21.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CEP07814.1 - 0.0012 19.0 0.8 0.0075 16.4 0.1 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 CEP07814.1 - 0.0012 18.3 0.3 0.005 16.3 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 CEP07814.1 - 0.0046 16.9 0.2 0.015 15.2 0.2 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 CEP07814.1 - 0.054 13.0 0.2 0.16 11.5 0.2 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CEP07814.1 - 0.095 12.2 0.1 0.39 10.2 0.0 2.0 2 1 1 3 3 3 0 NmrA-like family CH PF00307.31 CEP07815.1 - 5.9e-80 264.6 1.8 1.4e-20 73.5 0.1 4.6 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CEP07815.1 - 9.5e-13 47.8 0.1 0.00062 19.6 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_6 PF13405.6 CEP07815.1 - 1e-05 25.0 0.9 0.0042 16.9 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CEP07815.1 - 3.3e-05 24.2 0.6 0.00012 22.5 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP07815.1 - 0.00026 20.3 0.8 1.7 8.4 0.2 3.7 3 0 0 3 3 3 2 EF hand CH_2 PF06294.11 CEP07815.1 - 0.0075 16.4 0.2 3.1 8.0 0.0 3.6 3 0 0 3 3 3 1 CH-like domain in sperm protein MARVEL PF01284.23 CEP07816.1 - 0.046 13.8 11.4 0.11 12.6 11.4 1.7 1 1 0 1 1 1 0 Membrane-associating domain TPR_1 PF00515.28 CEP07819.1 - 3.3e-12 45.7 5.5 0.0002 21.0 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP07819.1 - 1.1e-05 25.1 1.9 1.4 9.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP07819.1 - 0.002 18.6 0.3 0.086 13.4 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP07819.1 - 0.0035 17.6 0.3 0.02 15.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.9 CEP07819.1 - 0.004 15.9 1.7 0.0061 15.4 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 CEP07819.1 - 0.0087 16.3 2.4 0.016 15.4 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEP07819.1 - 0.024 14.3 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 CEP07819.1 - 0.026 14.7 1.6 16 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP07819.1 - 0.028 14.7 0.9 34 4.8 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SpoU_sub_bind PF08032.12 CEP07819.1 - 0.87 9.9 3.8 2.1 8.7 3.8 1.6 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Scramblase PF03803.15 CEP07820.1 - 1.5e-53 181.4 0.2 2.1e-53 180.9 0.2 1.2 1 0 0 1 1 1 1 Scramblase Indigoidine_A PF04227.12 CEP07821.1 - 6.5e-125 416.3 5.3 7.7e-125 416.1 5.3 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein TPP_enzyme_N PF02776.18 CEP07821.1 - 0.038 13.6 0.4 0.21 11.2 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transglut_core PF01841.19 CEP07821.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily PX PF00787.24 CEP07822.1 - 4.7e-22 78.1 1.2 4.7e-22 78.1 1.2 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CEP07822.1 - 9.4e-11 41.7 5.5 5.4e-07 29.4 0.2 2.5 2 0 0 2 2 2 2 Vps5 C terminal like AKNA PF12443.8 CEP07822.1 - 0.016 15.8 0.3 0.016 15.8 0.3 2.4 3 0 0 3 3 3 0 AT-hook-containing transcription factor BLOC1_2 PF10046.9 CEP07822.1 - 0.018 15.3 4.3 0.13 12.6 0.1 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.13 CEP07822.1 - 0.89 9.7 8.5 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF4625 PF15418.6 CEP07823.1 - 0.0028 17.9 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) SARAF PF06682.12 CEP07824.1 - 0.073 12.7 0.4 0.086 12.5 0.4 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Integrase_H2C2 PF17921.1 CEP07825.1 - 1e-12 47.9 0.3 1.8e-12 47.1 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP07825.1 - 1.6e-06 28.3 0.0 2.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DNA_pol_A_exo1 PF01612.20 CEP07827.1 - 8.6e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease TALPID3 PF15324.6 CEP07829.1 - 0.48 8.0 7.7 0.65 7.6 7.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target TIMP PF00965.17 CEP07832.1 - 0.17 11.7 0.8 0.21 11.4 0.8 1.2 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase Tubulin-binding PF00418.19 CEP07834.1 - 1.2e-78 258.7 49.9 3.9e-11 42.8 1.0 9.0 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat ATP-synt_ab PF00006.25 CEP07834.1 - 7.7e-68 228.3 0.0 1.3e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEP07834.1 - 1.4e-09 38.3 0.5 3.3e-09 37.1 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 CEP07834.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF4162 PF13732.6 CEP07834.1 - 1.3 9.8 6.3 53 4.6 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4162) HrcA_DNA-bdg PF03444.15 CEP07834.1 - 2.8 7.7 5.7 24 4.7 0.0 4.4 6 0 0 6 6 6 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Arrestin_N PF00339.29 CEP07835.1 - 1.3e-08 35.0 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Homeodomain PF00046.29 CEP07836.1 - 5.6e-21 74.1 2.0 1.8e-20 72.5 2.0 2.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP07836.1 - 0.0016 18.3 1.8 0.0046 16.8 0.2 2.5 2 0 0 2 2 2 1 Homeobox KN domain CAP_N PF01213.19 CEP07836.1 - 2.2 7.7 21.0 0.61 9.5 5.7 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Tubulin PF00091.25 CEP07837.1 - 5.8e-68 229.0 0.0 1e-67 228.2 0.0 1.4 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP07837.1 - 4.6e-50 169.0 0.0 7.5e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEP07837.1 - 0.00041 20.1 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain bMG10 PF17973.1 CEP07837.1 - 0.12 12.6 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain Glyco_transf_15 PF01793.16 CEP07838.1 - 1.3e-53 182.4 11.7 1.7e-53 182.0 11.7 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TSC22 PF01166.18 CEP07839.1 - 1e-05 25.7 0.3 1e-05 25.7 0.3 2.1 2 0 0 2 2 2 1 TSC-22/dip/bun family NTP_transf_4 PF13562.6 CEP07839.1 - 0.001 19.3 0.8 0.0013 19.0 0.8 1.2 1 0 0 1 1 1 1 Sugar nucleotidyl transferase YabA PF06156.13 CEP07839.1 - 0.0064 17.1 6.5 0.018 15.7 6.5 1.7 1 1 0 1 1 1 1 Initiation control protein YabA RasGAP_C PF03836.15 CEP07839.1 - 0.016 15.3 6.7 0.026 14.7 6.7 1.3 1 0 0 1 1 1 0 RasGAP C-terminus DivIC PF04977.15 CEP07839.1 - 0.027 14.2 0.6 0.027 14.2 0.6 2.1 1 1 0 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.12 CEP07839.1 - 0.083 12.8 0.1 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ADIP PF11559.8 CEP07839.1 - 0.1 12.7 12.4 0.15 12.2 12.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 CEP07839.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper GW PF13457.6 CEP07839.1 - 0.15 12.7 8.0 6.9 7.4 0.0 2.2 1 1 1 2 2 2 0 GW (Gly-Tryp) dipeptide domain ZapB PF06005.12 CEP07839.1 - 0.16 12.5 9.1 1.9 9.0 9.1 2.1 1 1 0 1 1 1 0 Cell division protein ZapB DUF4472 PF14739.6 CEP07839.1 - 0.17 12.7 6.7 0.09 13.5 4.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Baculo_p24 PF05073.12 CEP07839.1 - 0.3 10.9 6.4 0.31 10.8 3.8 1.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Nnf1 PF03980.14 CEP07839.1 - 0.3 11.5 6.8 0.62 10.5 6.8 1.5 1 1 0 1 1 1 0 Nnf1 CENP-H PF05837.12 CEP07839.1 - 0.35 11.3 12.7 0.65 10.4 2.9 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cnn_1N PF07989.11 CEP07839.1 - 1 9.6 7.8 1.4 9.1 0.3 2.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 CEP07839.1 - 1.9 9.4 9.3 13 6.7 0.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Helitron_like_N PF14214.6 CEP07840.1 - 1.2e-53 182.2 0.0 1.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3287 PF11690.8 CEP07841.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF1957 PF09210.11 CEP07841.1 - 0.14 12.6 0.6 2 8.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Dam PF05869.11 CEP07842.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) PARM PF17061.5 CEP07844.1 - 0.018 15.2 4.2 0.027 14.6 4.2 1.2 1 0 0 1 1 1 0 PARM SH3_1 PF00018.28 CEP07845.1 - 1.4e-11 43.8 0.0 2.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP07845.1 - 7.6e-10 38.3 0.0 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP07845.1 - 2.3e-09 37.0 0.0 3.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M17 PF00883.21 CEP07846.1 - 6.8e-122 406.6 0.2 9.3e-122 406.2 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CEP07846.1 - 2.6e-12 46.7 0.8 4.8e-12 45.8 0.8 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Mitofilin PF09731.9 CEP07847.1 - 3e-77 260.9 40.9 1.4e-65 222.3 37.2 2.1 1 1 0 2 2 2 2 Mitochondrial inner membrane protein DUF465 PF04325.13 CEP07847.1 - 2.4 8.3 18.2 0.99 9.5 1.2 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF465) rve PF00665.26 CEP07848.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP07848.1 - 0.044 13.9 1.4 0.044 13.9 1.4 2.1 2 1 0 2 2 2 0 Integrase zinc binding domain Gp-FAR-1 PF05823.12 CEP07849.1 - 0.0026 18.1 1.4 0.0026 18.1 1.4 1.9 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PKK PF12474.8 CEP07849.1 - 0.0071 16.5 2.9 0.0071 16.5 2.9 2.6 3 0 0 3 3 3 1 Polo kinase kinase Mating_N PF12731.7 CEP07849.1 - 0.044 13.9 1.5 3.2 7.9 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 FAM92 PF06730.11 CEP07849.1 - 0.05 13.0 8.0 0.048 13.1 1.0 3.0 1 1 1 3 3 3 0 FAM92 protein DUF725 PF05267.12 CEP07849.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.4 3 1 0 4 4 4 0 Protein of unknown function (DUF725) FAM184 PF15665.5 CEP07849.1 - 0.53 10.0 9.7 0.5 10.1 7.3 2.2 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B ATG16 PF08614.11 CEP07849.1 - 1.7 8.8 14.8 0.27 11.4 8.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 CEP07849.1 - 5.7 6.9 11.3 1.1 9.2 2.7 3.1 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 CEP07849.1 - 5.7 7.5 7.9 54 4.3 7.8 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Phosphorylase PF00343.20 CEP07850.1 - 0 1034.8 0.0 0 1034.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase zf-H2C2_2 PF13465.6 CEP07851.1 - 8e-11 41.9 13.8 3.1e-06 27.3 0.3 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP07851.1 - 2e-09 37.4 13.6 5.3e-05 23.4 2.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP07851.1 - 4.3e-07 30.2 7.2 0.0048 17.6 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP07851.1 - 6.4e-05 23.1 0.5 0.00033 20.8 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CEP07851.1 - 0.00029 20.5 0.6 0.039 13.7 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 CEP07851.1 - 0.00085 19.6 2.0 0.0043 17.4 0.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEP07851.1 - 0.0011 18.9 3.7 0.63 10.1 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEP07851.1 - 0.089 12.6 0.2 0.089 12.6 0.2 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 CEP07851.1 - 0.22 11.6 3.8 13 5.9 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger F-box-like PF12937.7 CEP07852.1 - 7.9e-05 22.5 0.1 0.0002 21.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07852.1 - 0.015 15.1 0.5 0.041 13.8 0.5 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 CEP07852.1 - 0.029 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 PRANC domain F-box_4 PF15966.5 CEP07852.1 - 0.039 13.8 0.3 0.13 12.1 0.3 1.9 1 1 0 1 1 1 0 F-box DUF1040 PF06288.13 CEP07853.1 - 0.015 15.6 3.5 0.41 11.1 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF1040) Hemerythrin PF01814.23 CEP07853.1 - 0.094 13.3 2.2 0.54 10.9 0.1 2.9 2 1 2 4 4 4 0 Hemerythrin HHE cation binding domain HopJ PF08888.11 CEP07853.1 - 0.22 11.8 2.3 9.2 6.5 0.3 2.5 2 0 0 2 2 2 0 HopJ type III effector protein Seryl_tRNA_N PF02403.22 CEP07853.1 - 0.3 11.3 30.5 0.45 10.8 1.2 4.9 1 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DED PF01335.21 CEP07853.1 - 0.5 10.7 0.1 0.5 10.7 0.1 3.1 3 0 0 3 3 3 0 Death effector domain BLOC1_2 PF10046.9 CEP07853.1 - 0.67 10.3 26.4 5.4 7.4 1.5 5.4 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MMPL PF03176.15 CEP07853.1 - 1.2 8.0 6.7 1.2 8.0 0.4 2.5 1 1 2 3 3 3 0 MMPL family ApoC-I PF04691.12 CEP07853.1 - 4.1 7.4 8.3 12 6.0 0.6 4.1 4 1 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) 2OG-FeII_Oxy_2 PF13532.6 CEP07854.1 - 2.5e-20 73.5 0.0 2.7e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-U1 PF06220.12 CEP07855.1 - 2.4e-05 24.0 10.0 0.0026 17.5 10.0 2.3 1 1 0 1 1 1 1 U1 zinc finger LPD39 PF18858.1 CEP07855.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 zinc_ribbon_10 PF10058.9 CEP07856.1 - 2e-18 65.8 0.5 3.3e-18 65.1 0.5 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF2663 PF10864.8 CEP07856.1 - 0.009 16.4 2.3 0.02 15.3 1.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2663) Comm PF15957.5 CEP07856.1 - 0.02 15.3 0.3 0.02 15.3 0.3 2.1 3 0 0 3 3 3 0 Commissureless Zn_ribbon_SprT PF17283.2 CEP07856.1 - 0.056 13.4 1.5 0.15 12.0 1.5 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain DUF3810 PF12725.7 CEP07856.1 - 0.069 12.5 0.4 0.16 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Kei1 PF08552.11 CEP07856.1 - 0.089 12.7 0.0 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MRP-L46 PF11788.8 CEP07856.1 - 2.4 8.9 17.8 1.3 9.8 9.5 2.6 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 DPM3 PF08285.11 CEP07856.1 - 5.6 7.2 5.7 0.47 10.7 0.2 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ctr PF04145.15 CEP07857.1 - 1.6e-15 58.0 0.0 1.8e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FHA PF00498.26 CEP07858.1 - 1.3e-16 60.7 0.5 2.7e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 FHA domain zf-RING_11 PF17123.5 CEP07858.1 - 2.8e-10 39.8 11.8 5.7e-10 38.8 11.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEP07858.1 - 2.2e-07 31.1 10.8 4.1e-07 30.2 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 CEP07858.1 - 0.00038 20.7 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 CEP07858.1 - 0.0016 18.3 12.3 0.0028 17.5 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP07858.1 - 0.013 15.4 10.6 0.026 14.4 10.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP07858.1 - 0.026 14.8 11.0 0.086 13.1 11.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEP07858.1 - 0.039 13.9 9.8 0.084 12.8 9.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP07858.1 - 0.25 11.4 4.2 0.59 10.2 4.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEP07858.1 - 1.4 9.0 11.1 1.1 9.4 9.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 CEP07858.1 - 1.6 8.7 9.3 0.86 9.5 6.8 1.9 2 0 0 2 2 2 0 PHD-finger Ribosomal_L32e PF01655.18 CEP07859.1 - 3.8e-49 165.6 0.5 4.6e-49 165.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 eIF3g PF12353.8 CEP07860.1 - 0.00024 21.5 4.1 0.00048 20.5 4.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.6 CEP07860.1 - 0.042 13.7 2.1 0.097 12.5 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP07860.1 - 0.046 13.7 1.2 0.074 13.0 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP07860.1 - 0.15 12.2 5.2 1 9.5 5.2 2.3 1 1 0 1 1 1 0 Zinc knuckle OrfB_Zn_ribbon PF07282.11 CEP07860.1 - 0.64 10.0 2.7 0.85 9.6 1.4 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain V-SNARE_C PF12352.8 CEP07862.1 - 3.1e-13 49.8 1.6 3.1e-13 49.8 1.6 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CEP07862.1 - 1.2e-06 28.3 0.1 3.7e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Sec20 KxDL PF10241.9 CEP07862.1 - 0.017 15.4 0.7 0.017 15.4 0.7 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein Syntaxin-18_N PF10496.9 CEP07862.1 - 0.037 14.3 4.0 0.17 12.1 4.0 2.1 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus RabGAP-TBC PF00566.18 CEP07863.1 - 2.3e-47 161.4 0.3 2.3e-47 161.4 0.3 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 CEP07863.1 - 2.4e-28 98.3 2.9 8.5e-19 67.5 0.7 2.8 2 0 0 2 2 2 2 GRAM domain EF-hand_6 PF13405.6 CEP07863.1 - 0.00077 19.2 1.5 0.2 11.7 0.7 3.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEP07863.1 - 0.0043 16.5 0.6 0.19 11.4 0.7 3.3 2 0 0 2 2 2 1 EF hand PH_TFIIH PF08567.11 CEP07863.1 - 0.58 10.5 3.3 3.2 8.2 0.0 3.4 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain CNH PF00780.22 CEP07864.1 - 6.3e-45 153.9 0.0 1.2e-44 153.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP07864.1 - 2.1e-32 112.8 0.2 2.1e-32 112.8 0.2 2.8 3 1 0 3 3 3 1 RhoGEF domain PH_5 PF15405.6 CEP07864.1 - 5.5e-22 78.3 0.1 5.5e-22 78.3 0.1 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain DEP PF00610.21 CEP07864.1 - 4.3e-08 33.1 0.0 1.3e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.6 CEP07864.1 - 0.067 13.5 0.2 1.6 9.0 0.0 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain CsbD PF05532.12 CEP07865.1 - 2.6e-11 43.3 1.5 2.7e-11 43.2 1.5 1.1 1 0 0 1 1 1 1 CsbD-like ANTH PF07651.16 CEP07866.1 - 5e-75 252.0 0.0 5e-75 252.0 0.0 3.6 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 CEP07866.1 - 2.5e-53 180.4 12.4 2.5e-53 180.4 12.4 5.9 4 2 2 6 6 6 1 I/LWEQ domain ENTH PF01417.20 CEP07866.1 - 0.0014 18.6 0.6 0.0097 16.0 0.0 2.8 2 0 0 2 2 2 1 ENTH domain IATP PF04568.12 CEP07867.1 - 1.2e-07 32.0 1.8 1.5e-07 31.7 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Spc7 PF08317.11 CEP07867.1 - 0.0021 17.0 1.9 0.0023 16.9 1.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 CEP07867.1 - 0.045 14.4 1.1 0.19 12.3 0.8 1.9 1 1 1 2 2 2 0 SlyX DUF4140 PF13600.6 CEP07867.1 - 0.15 12.5 3.6 0.23 11.9 3.6 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PIF1 PF05970.14 CEP07868.1 - 3.4e-24 85.7 0.1 3.9e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF4007 PF13182.6 CEP07869.1 - 0.21 10.7 1.4 2 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) Tsp45I PF06300.12 CEP07870.1 - 0.0049 16.4 0.4 1.3 8.5 0.0 2.0 2 0 0 2 2 2 2 Tsp45I type II restriction enzyme RTT107_BRCT_5 PF16770.5 CEP07870.1 - 0.024 14.5 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Mito_fiss_Elm1 PF06258.11 CEP07871.1 - 4.5e-25 88.4 0.0 6.2e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 DXP_reductoisom PF02670.16 CEP07871.1 - 0.11 13.2 0.0 0.61 10.8 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TPP_enzyme_N PF02776.18 CEP07872.1 - 3.3e-50 170.0 0.1 1.9e-48 164.3 0.0 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEP07872.1 - 5.5e-40 136.3 0.0 1.1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CEP07872.1 - 3.3e-26 91.9 0.1 1.8e-25 89.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PNTB PF02233.16 CEP07872.1 - 0.0006 18.9 0.6 0.0022 17.0 0.1 2.1 3 0 0 3 3 3 1 NAD(P) transhydrogenase beta subunit Radical_SAM PF04055.21 CEP07872.1 - 0.0063 16.9 0.0 0.12 12.8 0.0 2.7 3 0 0 3 3 3 1 Radical SAM superfamily DXP_synthase_N PF13292.6 CEP07872.1 - 0.02 14.1 0.1 0.049 12.8 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.16 CEP07872.1 - 0.022 14.5 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Cofilin_ADF PF00241.20 CEP07873.1 - 3.1e-09 36.7 0.0 9.8e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 CEP07873.1 - 3.5e-05 24.3 0.0 3.5e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CEP07873.1 - 0.073 13.5 2.1 0.26 11.7 0.0 2.9 2 1 1 3 3 3 0 Pleckstrin homology domain Mg_trans_NIPA PF05653.14 CEP07874.1 - 1.5e-97 326.3 25.5 2e-97 325.9 25.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEP07874.1 - 4.2e-06 27.0 5.8 4.2e-06 27.0 5.8 4.1 3 1 1 4 4 4 2 EamA-like transporter family DUF5362 PF17319.2 CEP07874.1 - 3.4 7.6 0.0 3.4 7.6 0.0 3.6 5 0 0 5 5 5 0 Family of unknown function (DUF5362) Inositol_P PF00459.25 CEP07877.1 - 5.8e-73 245.8 0.1 6.8e-73 245.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PAP1 PF08601.10 CEP07880.1 - 0.03 14.1 4.8 0.037 13.8 4.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3474 PF11960.8 CEP07880.1 - 0.14 12.4 0.5 0.17 12.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Podoplanin PF05808.11 CEP07880.1 - 1.4 9.0 4.3 1.7 8.7 4.3 1.1 1 0 0 1 1 1 0 Podoplanin RRM_1 PF00076.22 CEP07881.1 - 0.00021 21.0 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP07881.1 - 0.046 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CEP07881.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif SPT16 PF08644.11 CEP07881.1 - 0.52 10.5 6.3 1.2 9.3 6.3 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF2098 PF09871.9 CEP07881.1 - 1.4 9.3 4.7 0.62 10.4 2.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Beach PF02138.18 CEP07883.1 - 1.8e-123 411.3 0.0 3.2e-123 410.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain FYVE PF01363.21 CEP07883.1 - 1.5e-10 41.1 15.8 3e-10 40.1 15.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH_BEACH PF14844.6 CEP07883.1 - 6.3e-10 39.1 0.0 2.2e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CEP07883.1 - 1e-07 31.5 0.0 1e-07 31.5 0.0 4.0 4 2 1 5 5 5 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 CEP07883.1 - 5.7e-05 23.3 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 CEP07883.1 - 0.00092 18.5 2.5 0.0021 17.4 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 CEP07883.1 - 0.0034 18.2 10.0 2.6 9.1 0.4 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Aminotran_1_2 PF00155.21 CEP07884.1 - 1.9e-28 99.7 0.0 2.3e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP07884.1 - 0.00063 18.4 0.0 0.0046 15.5 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CEP07884.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Cyclin_N PF00134.23 CEP07885.1 - 2e-11 43.7 0.1 2.9e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP07885.1 - 1.6e-09 38.3 0.0 1.9e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin OPT PF03169.15 CEP07886.1 - 1.4e-183 611.9 44.6 1.6e-183 611.8 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEAD PF00270.29 CEP07887.1 - 6.3e-47 159.6 0.0 1.7e-46 158.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP07887.1 - 2.7e-31 108.2 0.0 7.7e-29 100.3 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SpoIIID PF12116.8 CEP07887.1 - 0.027 14.6 0.8 0.11 12.6 0.4 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D DHHW PF14286.6 CEP07887.1 - 8.3 5.6 0.0 8.3 5.6 0.0 3.8 4 0 0 4 4 4 0 DHHW protein ATP-synt_G PF04718.15 CEP07888.1 - 7.3e-22 78.1 0.7 9.9e-22 77.7 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF892 PF05974.12 CEP07889.1 - 0.0047 17.0 0.9 0.0054 16.8 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF892) DegS PF05384.11 CEP07889.1 - 0.0092 15.5 2.6 0.011 15.2 2.6 1.1 1 0 0 1 1 1 1 Sensor protein DegS THOC7 PF05615.13 CEP07889.1 - 0.011 16.1 2.4 0.013 15.7 2.4 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 FlgM PF04316.13 CEP07889.1 - 0.016 15.6 0.7 0.025 15.0 0.7 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF4047 PF13256.6 CEP07889.1 - 0.026 14.7 0.8 0.031 14.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Med9 PF07544.13 CEP07889.1 - 0.038 14.1 2.6 0.052 13.6 2.6 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF5320 PF17253.2 CEP07889.1 - 0.14 13.3 0.1 0.15 13.1 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DivIC PF04977.15 CEP07889.1 - 0.56 10.0 4.6 0.81 9.5 4.6 1.5 1 1 0 1 1 1 0 Septum formation initiator NTF2 PF02136.20 CEP07891.1 - 0.036 14.6 0.1 0.1 13.2 0.0 1.8 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Rhomboid PF01694.22 CEP07892.1 - 1.6e-05 24.9 6.9 2.3e-05 24.4 6.9 1.2 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 CEP07892.1 - 0.004 16.8 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 CEP07892.1 - 0.033 14.1 2.3 0.045 13.7 2.3 1.2 1 0 0 1 1 1 0 Der1-like family ThiW PF09512.10 CEP07892.1 - 0.6 10.2 6.6 3 7.9 2.4 2.3 1 1 1 2 2 2 0 Thiamine-precursor transporter protein (ThiW) COX4 PF02936.14 CEP07893.1 - 3.1e-40 137.4 0.0 3.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.10 CEP07893.1 - 0.84 10.3 4.3 15 6.3 0.2 2.8 2 1 1 3 3 3 0 HMG-box domain Prefoldin PF02996.17 CEP07894.1 - 5.6e-17 61.8 4.1 5.1e-16 58.7 4.1 2.0 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 CEP07894.1 - 3.9e-05 23.6 0.8 6e-05 23.0 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Scaffolding_pro PF11418.8 CEP07894.1 - 0.0027 18.2 0.3 0.0053 17.3 0.2 1.5 1 1 0 1 1 1 1 Phi29 scaffolding protein FadA PF09403.10 CEP07894.1 - 0.0032 17.9 3.2 1.1 9.8 0.1 2.3 2 0 0 2 2 2 2 Adhesion protein FadA HMMR_C PF15908.5 CEP07894.1 - 0.03 14.6 1.4 0.034 14.4 0.9 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal NPV_P10 PF05531.12 CEP07894.1 - 0.035 14.6 5.4 2.6 8.5 0.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 CEP07894.1 - 0.043 14.1 5.9 0.21 11.8 5.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 CEP07894.1 - 0.048 13.9 4.5 0.15 12.3 0.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ntox28 PF15605.6 CEP07894.1 - 0.054 13.7 0.7 7.8 6.8 0.1 2.2 1 1 0 2 2 2 0 Bacterial toxin 28 DUF1664 PF07889.12 CEP07894.1 - 0.059 13.4 5.7 0.83 9.7 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 CEP07894.1 - 0.061 13.3 8.1 0.34 10.9 1.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit TEX12 PF15219.6 CEP07894.1 - 0.074 13.4 0.6 0.24 11.8 0.2 1.9 1 1 1 2 2 2 0 Testis-expressed 12 Spc7 PF08317.11 CEP07894.1 - 0.1 11.5 4.7 0.41 9.5 4.7 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF883 PF05957.13 CEP07894.1 - 0.11 13.1 0.3 9.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 CEP07894.1 - 0.43 10.6 1.6 13 5.7 0.1 2.2 2 1 0 2 2 2 0 Apolipoprotein O CC2-LZ PF16516.5 CEP07894.1 - 0.48 10.8 6.9 1.6 9.1 0.8 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GIT_CC PF16559.5 CEP07894.1 - 0.7 9.8 8.8 1 9.3 2.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 CEP07894.1 - 1.2 9.4 6.8 25 5.1 6.8 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 CEP07895.1 - 4.5e-80 269.6 13.4 5.6e-80 269.2 1.6 2.6 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.13 CEP07895.1 - 3.9e-45 153.7 0.0 1.6e-44 151.7 0.0 2.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEP07895.1 - 4.9e-39 134.0 0.2 4.9e-39 134.0 0.2 3.2 3 1 0 3 3 3 1 Diaphanous FH3 Domain DUF4709 PF15821.5 CEP07895.1 - 0.075 13.3 2.9 0.65 10.3 1.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) GP24_25 PF17388.2 CEP07895.1 - 4.4 7.3 8.3 3.1 7.8 0.4 3.5 2 1 1 3 3 3 0 Tail assembly gene products 24 & 25 Sec16_C PF12931.7 CEP07896.1 - 3e-41 142.0 0.2 5.3e-41 141.2 0.2 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DZR PF12773.7 CEP07896.1 - 0.14 12.2 1.8 0.29 11.2 1.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon SWIRM PF04433.17 CEP07897.1 - 1e-29 102.7 0.1 3e-29 101.2 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CEP07897.1 - 9.3e-24 83.2 6.3 9.3e-24 83.2 6.3 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CEP07897.1 - 5.6e-14 52.1 0.0 1.9e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP07897.1 - 1.7e-08 34.6 1.2 5e-08 33.1 0.2 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 CEP07897.1 - 2e-05 24.3 4.7 3.9e-05 23.4 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_7 PF15963.5 CEP07897.1 - 0.011 15.6 1.5 0.04 13.8 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEP07897.1 - 0.012 15.8 0.2 0.03 14.5 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Zn_ribbon_2 PF12674.7 CEP07897.1 - 0.039 14.6 3.0 0.1 13.2 2.3 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Chordopox_RPO7 PF05864.12 CEP07897.1 - 0.15 12.3 0.9 0.36 11.1 0.9 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Methyltr_RsmB-F PF01189.17 CEP07899.1 - 1.3e-37 129.4 0.0 6.1e-36 124.0 0.0 2.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TraF PF13728.6 CEP07899.1 - 0.0081 16.0 0.6 0.023 14.6 0.6 1.8 1 0 0 1 1 1 1 F plasmid transfer operon protein PBP_like_2 PF12849.7 CEP07899.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain FtsJ PF01728.19 CEP07899.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase FHA PF00498.26 CEP07900.1 - 1.8e-13 50.6 0.1 1.8e-13 50.6 0.1 2.2 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 CEP07900.1 - 0.1 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PRCC PF10253.9 CEP07901.1 - 3.4e-17 64.0 24.7 1.8e-15 58.4 24.7 2.3 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting PPP4R2 PF09184.11 CEP07901.1 - 2.2 7.8 17.6 0.1 12.2 10.3 2.0 2 0 0 2 2 2 0 PPP4R2 WD40 PF00400.32 CEP07902.1 - 4.9e-16 58.8 10.6 0.0033 18.2 0.0 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07902.1 - 6.6e-06 26.3 0.2 0.75 10.1 0.0 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2451 PF10474.9 CEP07903.1 - 0.078 12.8 0.7 0.15 11.8 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DDE_3 PF13358.6 CEP07904.1 - 1.6e-25 89.6 0.2 1.1e-22 80.3 0.2 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 CEP07904.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease HTH_23 PF13384.6 CEP07904.1 - 0.049 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DAHP_snth_FXD PF18152.1 CEP07904.1 - 0.055 13.3 0.1 20 5.1 0.0 3.2 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain F-box-like PF12937.7 CEP07906.1 - 5.3e-11 42.2 0.2 1.1e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP07906.1 - 0.033 14.1 0.4 0.16 11.9 0.4 2.2 1 1 0 1 1 1 0 F-box domain FTH PF01827.27 CEP07906.1 - 0.053 13.3 0.8 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 FTH domain GST_N_3 PF13417.6 CEP07907.1 - 1.1e-17 64.2 0.0 2.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP07907.1 - 8.9e-16 58.0 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP07907.1 - 7.9e-14 51.7 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEP07907.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP07907.1 - 7.2e-06 26.1 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP07907.1 - 9.3e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CEP07907.1 - 0.017 15.4 0.0 0.17 12.2 0.0 2.1 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein Glutaredoxin PF00462.24 CEP07907.1 - 0.12 12.6 0.2 2 8.7 0.0 2.8 3 1 0 3 3 3 0 Glutaredoxin tRNA-synt_2c PF01411.19 CEP07908.1 - 2.7e-161 537.8 0.0 3.6e-161 537.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CEP07908.1 - 6.3e-14 51.8 0.1 1.4e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CEP07908.1 - 3.4e-05 24.3 1.5 9.2e-05 22.9 1.5 1.7 1 0 0 1 1 1 1 DHHA1 domain Ribosomal_L23eN PF03939.13 CEP07909.1 - 1.7e-22 79.4 8.4 3.1e-22 78.5 8.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CEP07909.1 - 6.7e-16 58.4 5.0 3.2e-15 56.2 2.6 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 DUF1323 PF07037.11 CEP07909.1 - 0.14 12.6 0.2 0.42 11.0 0.1 1.7 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) Oxysterol_BP PF01237.18 CEP07910.1 - 5.3e-113 377.6 4.1 1.8e-112 375.9 4.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CEP07910.1 - 1.9e-20 72.9 0.5 5.4e-20 71.5 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP07910.1 - 9e-07 29.4 0.3 9e-07 29.4 0.3 2.9 3 0 0 3 3 3 1 PH domain GOLD_2 PF13897.6 CEP07910.1 - 0.00032 21.2 5.7 0.0096 16.4 1.5 2.9 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 CEP07910.1 - 0.0047 16.9 0.1 0.0047 16.9 0.1 2.7 3 0 0 3 3 3 1 emp24/gp25L/p24 family/GOLD EF-hand_1 PF00036.32 CEP07911.1 - 2.4e-22 76.7 6.4 3.1e-05 23.2 0.0 5.9 5 1 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEP07911.1 - 2.5e-22 79.1 2.6 1.8e-09 37.9 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEP07911.1 - 9.3e-22 75.1 4.8 3.8e-05 23.3 0.0 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEP07911.1 - 3.1e-18 64.3 5.3 2.5e-05 23.6 0.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CEP07911.1 - 5.4e-15 55.0 3.4 2.6e-08 33.6 0.0 4.8 3 3 2 5 5 5 4 EF-hand domain pair Caleosin PF05042.13 CEP07911.1 - 0.054 13.4 3.9 0.17 11.8 1.2 2.8 1 1 2 3 3 3 0 Caleosin related protein RCR PF12273.8 CEP07911.1 - 0.087 13.5 13.0 0.13 12.9 13.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EF-hand_9 PF14658.6 CEP07911.1 - 0.1 12.9 0.2 3.6 8.0 0.0 2.9 3 2 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP07911.1 - 0.19 12.0 3.5 2 8.8 0.1 3.0 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region NUDIX PF00293.28 CEP07912.1 - 1.2e-16 60.9 0.0 7.7e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Ank_4 PF13637.6 CEP07912.1 - 1.1e-11 45.0 0.0 1.1e-07 32.3 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP07912.1 - 4.4e-11 43.2 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEP07912.1 - 2.9e-07 30.6 0.0 7.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.11 CEP07912.1 - 1.9e-06 27.4 1.9 3.9e-06 26.4 1.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_3 PF13606.6 CEP07912.1 - 8.4e-06 25.8 0.0 0.00028 21.1 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat NUDIX-like PF09296.11 CEP07912.1 - 0.00038 21.1 0.0 0.00083 20.0 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank PF00023.30 CEP07912.1 - 0.00074 19.9 0.0 0.01 16.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat PUB_1 PF18486.1 CEP07912.1 - 0.028 14.3 0.6 3.5 7.6 0.0 3.3 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain DZR PF12773.7 CEP07912.1 - 0.18 11.9 0.7 0.31 11.1 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF3535 PF12054.8 CEP07914.1 - 2.5e-113 379.6 1.3 3e-111 372.8 0.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CEP07914.1 - 3.4e-63 213.5 0.0 7.7e-63 212.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP07914.1 - 6.4e-16 58.7 0.0 2.5e-15 56.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CEP07914.1 - 1.2e-11 43.8 19.6 0.024 14.8 0.5 10.0 11 0 0 11 11 11 3 HEAT repeat TAF6_C PF07571.13 CEP07914.1 - 1.4e-05 25.3 0.4 0.69 10.3 0.0 5.3 6 0 0 6 6 6 2 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 CEP07914.1 - 0.00055 20.0 0.1 6.5 6.8 0.0 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP07914.1 - 0.0015 18.9 4.4 0.0068 16.8 0.1 4.3 5 1 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CEP07914.1 - 0.0018 18.9 0.1 2.5 8.7 0.1 3.5 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEP07914.1 - 0.055 14.0 12.7 0.41 11.2 0.1 6.4 7 0 0 7 7 7 0 HEAT-like repeat ACDC PF14733.6 CEP07914.1 - 0.15 12.4 0.2 3.9 7.8 0.0 3.1 2 1 0 2 2 2 0 AP2-coincident C-terminal zf-RING_UBOX PF13445.6 CEP07915.1 - 1.5e-07 31.3 5.9 4.8e-07 29.7 5.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEP07915.1 - 1.2e-06 28.2 12.4 2.3e-06 27.3 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP07915.1 - 5.5e-06 26.1 15.4 1.2e-05 25.1 15.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP07915.1 - 3.4e-05 23.6 11.0 5.9e-05 22.8 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP07915.1 - 0.0001 22.2 14.2 0.00022 21.1 14.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEP07915.1 - 0.00013 22.3 12.6 0.00013 22.3 12.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEP07915.1 - 0.00021 21.4 8.3 0.00064 19.8 8.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CEP07915.1 - 0.022 14.6 6.2 0.061 13.2 6.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CEP07915.1 - 0.029 14.5 6.9 0.061 13.5 6.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CEP07915.1 - 0.031 14.0 8.2 0.21 11.4 5.8 2.7 2 0 0 2 2 2 0 RING-like zinc finger PTCB-BRCT PF12738.7 CEP07915.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Prok-RING_4 PF14447.6 CEP07915.1 - 0.4 10.6 16.6 0.074 12.9 12.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 CEP07915.1 - 0.74 9.9 11.1 8 6.6 11.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon RabGAP-TBC PF00566.18 CEP07916.1 - 6.8e-30 104.3 1.0 6.8e-30 104.3 1.0 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SUIM_assoc PF16619.5 CEP07916.1 - 0.23 11.6 12.4 0.056 13.5 8.5 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GRP PF07172.11 CEP07916.1 - 4.6 8.0 14.1 10 6.9 14.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family Med3 PF11593.8 CEP07916.1 - 8.7 5.4 19.6 15 4.7 19.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SCP2 PF02036.17 CEP07917.1 - 1.4e-23 83.3 1.1 1.6e-23 83.1 1.1 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CEP07917.1 - 0.00088 19.5 0.2 0.0012 19.1 0.2 1.2 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 CEP07917.1 - 0.017 15.5 0.0 0.023 15.1 0.0 1.3 1 1 0 1 1 1 0 Sterol carrier protein domain Peptidase_C107 PF17222.3 CEP07917.1 - 0.084 11.9 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Big_6 PF17936.1 CEP07917.1 - 0.3 11.4 1.8 0.61 10.4 0.6 1.9 1 1 1 2 2 2 0 Bacterial Ig domain Isochorismatase PF00857.20 CEP07919.1 - 3.2e-24 86.0 0.0 5.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Allantoicase PF03561.15 CEP07920.1 - 9.9e-44 148.8 0.0 2.7e-20 72.8 0.0 3.1 2 2 1 3 3 3 2 Allantoicase repeat TRAPP PF04051.16 CEP07921.1 - 8.4e-48 161.8 0.0 1e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SUI1 PF01253.22 CEP07922.1 - 8.6e-19 67.8 2.0 3.7e-18 65.8 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CEP07922.1 - 2.2e-13 50.7 0.9 6.2e-12 46.0 0.0 3.3 3 0 0 3 3 3 1 Pre-PUA-like domain SWIB PF02201.18 CEP07922.1 - 0.0011 18.9 0.3 0.0033 17.3 0.3 1.9 1 1 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 CEP07922.1 - 0.0014 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.9 CEP07922.1 - 0.0019 18.1 1.8 0.0021 18.0 0.1 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein Abhydrolase_3 PF07859.13 CEP07923.1 - 2.1e-17 63.7 0.1 4e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CEP07923.1 - 1.2e-16 60.7 0.9 1.6e-15 57.0 0.9 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CEP07923.1 - 2.6e-10 40.1 0.1 0.0001 21.8 0.0 3.0 2 1 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 CEP07923.1 - 5.5e-06 25.7 0.1 7.6e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 CEP07923.1 - 6.8e-06 25.2 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CEP07923.1 - 0.00025 20.4 0.1 0.0012 18.2 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP07923.1 - 0.0021 18.7 0.0 0.0028 18.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 CEP07923.1 - 0.0078 15.3 0.1 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 Chlorophyllase LIDHydrolase PF10230.9 CEP07923.1 - 0.025 14.1 0.3 0.12 11.9 0.2 1.9 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CEP07923.1 - 0.055 13.3 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Say1_Mug180 PF10340.9 CEP07923.1 - 0.081 11.8 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase PAF-AH_p_II PF03403.13 CEP07923.1 - 0.15 10.6 0.3 1.3 7.4 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SAP PF02037.27 CEP07924.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain WRKY PF03106.15 CEP07925.1 - 0.012 15.8 0.7 0.032 14.5 0.7 1.7 1 0 0 1 1 1 0 WRKY DNA -binding domain DUF1932 PF09130.11 CEP07925.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Thr_synth_N PF14821.6 CEP07926.1 - 1.3e-28 99.0 0.0 2.7e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 CEP07926.1 - 3.3e-13 49.7 0.0 8.8e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF421 PF04239.12 CEP07926.1 - 0.12 12.1 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF421) NUP50 PF08911.11 CEP07926.1 - 0.14 12.9 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Arm PF00514.23 CEP07927.1 - 3.9e-08 33.0 1.1 1.3e-05 25.0 0.1 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEP07927.1 - 1.4e-06 28.7 0.3 0.17 12.4 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEP07927.1 - 0.023 15.3 0.0 16 6.2 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 CEP07927.1 - 0.045 13.7 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain YliH PF10799.8 CEP07927.1 - 0.095 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) HEAT PF02985.22 CEP07927.1 - 0.098 13.0 0.5 6.1 7.4 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat WAPL PF07814.13 CEP07927.1 - 2.4 6.9 6.4 16 4.1 0.6 3.2 2 1 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin MFS_1 PF07690.16 CEP07928.1 - 7.5e-13 48.1 27.1 7.5e-13 48.1 27.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 CEP07928.1 - 9.5e-12 44.9 3.3 9.5e-12 44.9 3.3 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Actin PF00022.19 CEP07929.1 - 1.3e-91 307.3 0.0 5.2e-90 302.0 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEP07929.1 - 3.4e-05 22.8 0.0 0.12 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein tRNA-synt_1c PF00749.21 CEP07930.1 - 0.054 12.4 4.8 0.11 11.3 4.8 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Senescence_reg PF04520.13 CEP07930.1 - 4.2 8.2 14.3 28 5.5 6.4 3.3 1 1 1 2 2 2 0 Senescence regulator Ras PF00071.22 CEP07931.1 - 5.8e-59 198.3 0.1 6.9e-59 198.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP07931.1 - 1.3e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP07931.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP07931.1 - 0.00026 20.6 0.1 0.00092 18.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP07931.1 - 0.00063 19.8 0.0 0.00099 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP07931.1 - 0.0014 18.5 0.0 0.84 9.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 CEP07931.1 - 0.076 12.7 0.7 1.2 8.9 0.1 2.4 2 1 1 3 3 3 0 IstB-like ATP binding protein FeoB_N PF02421.18 CEP07931.1 - 0.12 11.9 0.0 0.65 9.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CEP07931.1 - 0.23 11.1 1.1 0.85 9.3 0.2 2.2 2 1 0 2 2 2 0 AAA domain Ribosomal_S7e PF01251.18 CEP07932.1 - 1.8e-80 269.0 0.5 2.1e-80 268.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e IF4E PF01652.18 CEP07933.1 - 7.8e-55 185.0 2.0 9.4e-55 184.8 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DSS1_SEM1 PF05160.13 CEP07933.1 - 0.38 10.9 0.0 0.38 10.9 0.0 2.7 2 1 1 3 3 3 0 DSS1/SEM1 family Ribosomal_S6e PF01092.19 CEP07934.1 - 5.5e-58 194.4 0.1 5.5e-58 194.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e Nup192 PF11894.8 CEP07935.1 - 3e-197 657.9 30.4 5.4e-197 657.0 30.4 1.3 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 TFIIA PF03153.13 CEP07935.1 - 0.26 11.2 7.8 0.11 12.4 0.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMADHC PF10229.9 CEP07936.1 - 8e-17 61.9 0.0 9.1e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein VASt PF16016.5 CEP07937.1 - 1.9e-42 145.3 0.6 3.8e-42 144.3 0.6 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CEP07937.1 - 7e-25 87.1 0.0 1.9e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 GRAM domain FlaC_arch PF05377.11 CEP07937.1 - 0.23 11.9 1.3 0.84 10.1 1.3 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PA26 PF04636.13 CEP07939.1 - 2.7e-82 277.1 0.0 3.9e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF4286 PF14114.6 CEP07940.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF1757 PF08560.10 CEP07940.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) CTP_transf_like PF01467.26 CEP07943.1 - 1.4e-28 99.9 0.0 1.8e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like UQ_con PF00179.26 CEP07944.1 - 6.9e-17 61.4 0.0 7.4e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP07944.1 - 0.0093 16.2 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sld5 PF05916.11 CEP07945.1 - 2.2e-08 34.5 0.1 3.1e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Tim17 PF02466.19 CEP07946.1 - 1.7e-10 41.2 12.2 2.5e-10 40.7 12.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SF3b1 PF08920.10 CEP07947.1 - 1.1e-43 148.5 17.3 4e-43 146.7 2.9 3.4 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 CEP07947.1 - 8.7e-11 42.1 2.9 0.76 10.4 0.0 7.5 7 1 1 8 8 8 4 HEAT-like repeat HEAT PF02985.22 CEP07947.1 - 4.7e-10 38.8 5.6 1.7 9.1 0.0 8.6 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CEP07947.1 - 1.5e-09 38.1 7.0 0.22 11.9 0.0 7.7 4 2 5 9 9 9 3 HEAT repeats Dopey_N PF04118.14 CEP07947.1 - 2.7e-05 23.4 1.0 0.15 11.1 0.0 3.8 3 1 1 4 4 4 2 Dopey, N-terminal Adaptin_N PF01602.20 CEP07947.1 - 2.8e-05 22.9 3.4 0.025 13.1 0.1 3.2 2 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CEP07947.1 - 0.00015 22.3 4.1 1.2 9.7 0.0 4.6 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEP07947.1 - 0.00091 19.3 8.2 0.77 9.8 0.0 5.7 7 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 CEP07947.1 - 0.012 15.3 0.9 9.5 5.8 0.0 4.5 3 2 1 4 4 4 0 NUC173 domain CLASP_N PF12348.8 CEP07947.1 - 0.016 14.8 0.5 21 4.6 0.0 3.5 3 0 0 3 3 3 0 CLASP N terminal MMS19_C PF12460.8 CEP07947.1 - 0.019 14.1 0.0 8.2 5.4 0.0 3.7 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 CEP07947.1 - 0.02 15.2 0.0 0.097 13.0 0.0 2.3 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 CEP07947.1 - 0.045 13.8 0.4 59 3.9 0.0 4.9 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 CEP07947.1 - 0.097 12.2 0.2 5.8 6.4 0.0 3.0 2 1 1 3 3 3 0 Tti2 family Pribosyl_synth PF14572.6 CEP07948.1 - 1.2e-39 136.3 1.3 1.6e-33 116.3 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CEP07948.1 - 2.4e-37 127.4 0.0 2.2e-35 121.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CEP07948.1 - 4e-13 49.2 0.2 6.8e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEP07948.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HTH_17 PF12728.7 CEP07948.1 - 0.12 12.6 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CxC2 PF18803.1 CEP07949.1 - 2.9e-06 27.4 0.8 1.3e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Swm2 PF17083.5 CEP07949.1 - 0.059 13.4 1.7 1.1 9.3 0.3 2.7 3 0 0 3 3 3 0 Nucleolar protein Swm2 AA_permease_2 PF13520.6 CEP07950.1 - 2.4e-07 29.9 3.3 2.9e-07 29.7 3.3 1.1 1 0 0 1 1 1 1 Amino acid permease BofA PF07441.11 CEP07950.1 - 0.086 13.1 4.4 3.6 7.9 0.2 2.3 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Collectrin PF16959.5 CEP07950.1 - 0.14 11.9 1.0 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Homeodomain PF00046.29 CEP07951.1 - 5.3e-19 67.8 3.4 6.9e-19 67.5 2.0 1.9 2 0 0 2 2 2 1 Homeodomain DUF3678 PF12435.8 CEP07951.1 - 0.087 12.2 3.2 0.69 9.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Ribosomal_60s PF00428.19 CEP07951.1 - 0.91 10.1 9.2 1.7 9.3 1.9 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PH PF00169.29 CEP07952.1 - 5.2e-10 39.8 1.1 7.2e-10 39.3 0.1 1.7 2 0 0 2 2 2 1 PH domain PIN_4 PF13638.6 CEP07953.1 - 1.9e-27 96.1 0.6 3.5e-27 95.3 0.1 1.7 2 0 0 2 2 2 1 PIN domain Inj_translocase PF16928.5 CEP07953.1 - 0.73 9.2 4.5 14 5.1 4.1 2.4 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome Ank_2 PF12796.7 CEP07954.1 - 8.1e-44 148.1 6.6 3e-14 53.4 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) DHHC PF01529.20 CEP07954.1 - 2.9e-33 114.8 11.5 2.9e-33 114.8 11.5 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CEP07954.1 - 4.9e-28 97.1 1.9 3.9e-08 33.7 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP07954.1 - 4.4e-25 87.4 1.3 3.6e-07 30.3 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CEP07954.1 - 4.4e-24 83.8 4.5 1e-05 25.8 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 CEP07954.1 - 9.4e-23 77.8 0.9 0.017 15.6 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat RHD3 PF05879.12 CEP07956.1 - 7.6e-244 811.3 8.6 1.5e-208 694.6 5.0 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CEP07956.1 - 4.7e-06 26.8 0.2 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CEP07956.1 - 1.5e-05 25.1 0.0 5.8e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 CEP07956.1 - 2.8e-05 23.5 0.2 5.9e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain LXG PF04740.12 CEP07956.1 - 0.0092 15.7 0.4 0.025 14.3 0.4 1.7 1 0 0 1 1 1 1 LXG domain of WXG superfamily AAA_28 PF13521.6 CEP07956.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF5123 PF17161.4 CEP07956.1 - 0.11 13.6 1.9 9.3 7.4 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) CompInhib_SCIN PF11546.8 CEP07956.1 - 0.3 11.2 3.3 1.9 8.6 0.3 2.9 2 1 0 2 2 2 0 Staphylococcal complement inhibitor SCIN Baculo_PEP_C PF04513.12 CEP07956.1 - 0.32 11.0 1.8 0.5 10.4 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cnd1 PF12717.7 CEP07957.1 - 2e-06 28.0 2.1 5e-05 23.4 0.1 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEP07957.1 - 6.4e-05 23.4 4.2 0.0049 17.3 0.3 4.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.22 CEP07957.1 - 0.00045 20.2 0.4 0.095 13.0 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.23 CEP07957.1 - 0.0021 18.0 0.1 0.0021 18.0 0.1 4.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP07957.1 - 0.013 15.9 1.6 0.3 11.5 0.7 3.0 2 1 0 2 2 2 0 HEAT repeats DUF1427 PF07235.11 CEP07957.1 - 0.059 13.3 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) TAF6_C PF07571.13 CEP07957.1 - 0.16 12.3 0.1 0.97 9.8 0.1 2.4 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain ADP_ribosyl_GH PF03747.14 CEP07957.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase MFS_1 PF07690.16 CEP07958.1 - 1.7e-13 50.2 31.1 2.4e-13 49.7 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CEP07958.1 - 3.9e-12 46.2 1.1 3.9e-12 46.2 1.1 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 SWIRM PF04433.17 CEP07959.1 - 1.6e-08 34.7 0.0 4.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain HYLS1_C PF15311.6 CEP07959.1 - 0.096 13.5 0.6 0.096 13.5 0.6 2.2 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Hydrolase_4 PF12146.8 CEP07959.1 - 0.14 11.4 0.3 0.21 10.8 0.3 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 CEP07960.1 - 4.4e-14 52.6 7.3 0.00054 20.7 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP07960.1 - 1.7e-06 28.2 0.0 0.14 12.5 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CEP07960.1 - 0.0074 16.2 0.0 0.98 9.4 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat SUIM_assoc PF16619.5 CEP07960.1 - 0.016 15.3 5.2 0.069 13.2 5.2 2.2 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 eIF2A PF08662.11 CEP07960.1 - 0.061 13.2 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CEP07960.1 - 0.098 11.2 0.0 0.18 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain PAS_3 PF08447.12 CEP07961.1 - 1.4e-15 57.4 0.0 3.4e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 CEP07961.1 - 2.7e-14 52.5 7.4 5.2e-14 51.6 7.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 CEP07961.1 - 5.8e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CEP07961.1 - 3.6e-08 33.6 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CEP07961.1 - 3.7e-07 30.3 0.0 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 CEP07961.1 - 9.1e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain TF_Zn_Ribbon PF08271.12 CEP07961.1 - 0.31 10.6 1.7 1.8 8.1 0.5 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding COX7a PF02238.15 CEP07962.1 - 3.3e-19 69.0 0.0 5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII WRKY PF03106.15 CEP07963.1 - 5.5e-10 39.3 1.5 1.4e-09 38.1 1.5 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain Use1 PF09753.9 CEP07963.1 - 5 6.8 7.3 9 5.9 7.3 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 Svf1_C PF17187.4 CEP07964.1 - 9.7e-52 175.1 1.1 1.6e-51 174.4 1.1 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CEP07964.1 - 3.2e-36 124.9 1.6 7.8e-36 123.6 0.4 2.0 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain PDZ_4 PF17816.1 CEP07964.1 - 0.088 13.2 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PHD PF00628.29 CEP07966.1 - 4.2e-08 33.0 8.0 4.2e-08 33.0 8.0 2.4 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 CEP07966.1 - 0.0056 16.2 8.9 0.012 15.2 8.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CEP07966.1 - 0.063 13.3 8.2 0.16 12.1 6.3 2.5 2 0 0 2 2 2 0 CW-type Zinc Finger DUF4611 PF15387.6 CEP07966.1 - 0.25 11.6 5.7 1.4 9.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Ndc1_Nup PF09531.10 CEP07966.1 - 8.8 4.9 9.1 10 4.6 9.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Porph_ging PF09697.10 CEP07966.1 - 8.8 6.9 6.8 3.9 8.1 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) HEAT PF02985.22 CEP07968.1 - 6.5e-15 54.0 8.7 0.0048 17.0 0.1 7.4 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 CEP07968.1 - 1.6e-07 31.6 2.0 0.0011 19.4 0.0 5.2 5 2 2 7 7 7 2 HEAT repeats Cnd1 PF12717.7 CEP07968.1 - 8.7e-06 25.9 1.9 0.0027 17.8 0.0 4.0 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CEP07968.1 - 0.0026 18.2 3.4 19 5.9 0.0 4.9 4 1 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEP07968.1 - 0.036 14.6 3.1 51 4.6 0.1 4.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Not3 PF04065.15 CEP07969.1 - 8.3e-91 303.5 28.3 1.7e-90 302.5 28.3 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CEP07969.1 - 8.7e-46 155.3 12.2 3e-45 153.5 12.2 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family SesA PF17107.5 CEP07969.1 - 0.054 13.7 5.0 0.14 12.3 0.9 2.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2373 PF10180.9 CEP07969.1 - 0.19 11.6 3.4 0.57 10.1 3.4 1.9 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) FAM212 PF15342.6 CEP07969.1 - 0.2 11.4 1.2 13 5.7 0.2 2.8 2 0 0 2 2 2 0 FAM212 family DUF1192 PF06698.11 CEP07969.1 - 1.6 8.8 8.7 5.3 7.2 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.6 CEP07969.1 - 4.6 7.7 14.6 0.31 11.4 5.8 2.9 1 1 1 2 2 2 0 Syntaxin-like protein EVI2A PF05399.11 CEP07969.1 - 5.8 6.4 9.4 1.3 8.5 4.8 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) VTC PF09359.10 CEP07970.1 - 3.9e-85 285.6 0.2 6.1e-85 284.9 0.2 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CEP07970.1 - 1.5e-17 64.7 3.9 2.8e-09 37.4 0.1 3.5 1 1 2 3 3 3 3 SPX domain Sda PF08970.10 CEP07970.1 - 0.021 14.5 0.2 0.6 9.9 0.4 2.9 3 0 0 3 3 3 0 Sporulation inhibitor A VTC PF09359.10 CEP07971.1 - 1.8e-38 132.5 0.0 4.8e-38 131.1 0.0 1.8 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CEP07971.1 - 5.7e-14 52.3 4.3 1.2e-13 51.2 4.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) N6_N4_Mtase PF01555.18 CEP07971.1 - 1.5e-09 37.9 0.6 0.00052 19.8 0.0 3.3 3 0 0 3 3 3 2 DNA methylase GATA PF00320.27 CEP07971.1 - 0.0024 17.5 0.8 0.0024 17.5 0.8 3.3 4 0 0 4 4 4 1 GATA zinc finger MBT PF02820.18 CEP07971.1 - 0.091 13.1 0.1 23 5.4 0.0 3.2 3 0 0 3 3 3 0 mbt repeat DNA_pol_B_thumb PF14791.6 CEP07972.1 - 5.5e-17 61.7 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CEP07972.1 - 1.4e-15 56.9 0.1 5e-14 51.8 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CEP07972.1 - 4.4e-13 49.4 0.3 1e-12 48.2 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 CEP07972.1 - 6.3e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm Colicin-DNase PF12639.7 CEP07972.1 - 0.025 15.4 0.2 1.8 9.4 0.1 2.5 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin HHH_5 PF14520.6 CEP07972.1 - 0.025 15.2 0.0 1.1 9.9 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.23 CEP07972.1 - 0.15 12.0 0.0 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 CEP07972.1 - 0.19 12.1 0.6 1.7 9.2 0.1 2.7 3 0 0 3 3 3 0 IMS family HHH motif Antimicrobial22 PF16047.5 CEP07972.1 - 9.6 6.2 5.7 22 5.1 0.4 2.3 2 0 0 2 2 2 0 Frog antimicrobial peptide RVT_1 PF00078.27 CEP07973.1 - 8.7e-09 35.2 0.0 0.00034 20.2 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.27 CEP07974.1 - 1.5e-48 164.8 0.0 5.7e-25 88.4 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEP07974.1 - 7.8e-17 62.0 4.1 0.00033 20.6 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP07974.1 - 2.3e-13 50.1 4.2 0.013 15.0 0.0 4.7 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEP07974.1 - 1.9e-09 38.3 1.1 0.0017 18.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CEP07974.1 - 2.3e-08 33.7 0.3 0.0046 16.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP07974.1 - 2.9e-08 33.8 0.6 0.016 15.1 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CEP07974.1 - 1.1e-07 32.0 0.0 0.036 14.1 0.0 3.4 3 0 0 3 3 2 2 50S ribosome-binding GTPase Chromo PF00385.24 CEP07974.1 - 1.5e-07 31.2 0.2 3.6e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 CEP07974.1 - 1.2e-05 25.6 0.3 0.21 11.8 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CEP07974.1 - 2.4e-05 24.8 0.3 0.42 11.0 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.23 CEP07974.1 - 3e-05 24.1 0.0 0.07 13.2 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_28 PF13521.6 CEP07974.1 - 0.00012 22.4 0.0 0.028 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CEP07974.1 - 0.00028 20.7 1.1 1.2 8.8 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain MeaB PF03308.16 CEP07974.1 - 0.00061 18.9 0.1 0.18 10.7 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CEP07974.1 - 0.0011 19.1 3.9 1.5 9.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 CEP07974.1 - 0.0012 19.4 0.0 2 9.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CEP07974.1 - 0.0013 19.1 0.0 4 7.9 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 CEP07974.1 - 0.0019 17.8 0.0 2.7 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEP07974.1 - 0.0027 17.5 0.6 0.96 9.1 0.1 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CEP07974.1 - 0.0029 16.9 0.2 1.2 8.3 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin CLASP_N PF12348.8 CEP07974.1 - 0.0033 17.0 0.1 0.59 9.7 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal AAA_24 PF13479.6 CEP07974.1 - 0.0052 16.5 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 CEP07974.1 - 0.0054 16.9 2.0 1.3 9.1 0.4 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain 4HB PF17947.1 CEP07974.1 - 0.0084 16.1 0.0 0.039 14.0 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain NACHT PF05729.12 CEP07974.1 - 0.011 15.7 0.2 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 CEP07974.1 - 0.015 15.5 0.2 2.8 8.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 CEP07974.1 - 0.019 15.2 0.0 14 5.9 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CEP07974.1 - 0.021 14.1 0.1 8.6 5.6 0.0 3.0 3 0 0 3 3 3 0 Septin AAA_7 PF12775.7 CEP07974.1 - 0.029 13.9 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region UME PF08064.13 CEP07974.1 - 0.033 14.1 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain Ploopntkinase3 PF18751.1 CEP07974.1 - 0.048 13.6 0.1 4 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 CEP07974.1 - 0.066 12.4 0.0 5.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 CEP07974.1 - 0.081 13.4 0.2 9.5 6.6 0.0 3.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CEP07974.1 - 0.088 12.4 2.4 18 4.9 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CEP07974.1 - 0.11 12.0 0.4 13 5.3 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 CEP07974.1 - 0.19 10.9 1.4 5 6.2 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 CEP07974.1 - 0.63 9.8 2.2 8.4 6.1 0.3 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PGAP1 PF07819.13 CEP07975.1 - 7.9e-77 258.1 0.1 1.3e-76 257.4 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CEP07975.1 - 6.2e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CEP07975.1 - 6.6e-06 25.8 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 CEP07975.1 - 2.5e-05 24.1 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP07975.1 - 0.00043 19.6 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 CEP07975.1 - 0.00099 18.4 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEP07975.1 - 0.0032 18.1 0.0 0.011 16.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CEP07975.1 - 0.0058 16.2 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CEP07975.1 - 0.015 15.2 0.1 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Thioesterase PF00975.20 CEP07975.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 CEP07975.1 - 0.19 11.4 0.0 0.44 10.1 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Ribosomal_S3Ae PF01015.18 CEP07976.1 - 5.9e-86 287.2 6.2 7.7e-86 286.8 6.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF496 PF04363.12 CEP07976.1 - 4.4 7.4 6.1 30 4.7 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF496) Ribosomal_S3_C PF00189.20 CEP07977.1 - 1.6e-22 79.8 1.1 5.9e-22 78.0 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CEP07977.1 - 1.4e-12 47.2 0.1 2.3e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CEP07977.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Rpp20 PF12328.8 CEP07978.1 - 8.5e-12 45.2 1.0 5.4e-07 29.6 0.0 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CEP07978.1 - 1e-07 31.6 1.0 1.7e-07 31.0 1.0 1.4 1 0 0 1 1 1 1 Alba TrmK PF04816.12 CEP07978.1 - 0.012 15.2 0.4 0.023 14.3 0.3 1.4 1 1 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 CEP07978.1 - 0.056 13.4 0.9 0.13 12.2 0.3 1.7 1 1 1 2 2 2 0 Methyltransferase domain GCFC PF07842.12 CEP07979.1 - 2.2e-12 47.2 0.7 2.4e-11 43.8 0.5 2.9 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Pro-NT_NN PF07421.11 CEP07979.1 - 5.2 7.3 10.1 0.11 12.8 1.0 2.8 3 0 0 3 3 3 0 Neurotensin/neuromedin N precursor Tim44 PF04280.15 CEP07980.1 - 1.1e-23 84.0 0.2 1.5e-23 83.5 0.2 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 CEP07980.1 - 1.6e-10 40.4 0.4 2e-10 40.1 0.4 1.1 1 0 0 1 1 1 1 MBA1-like protein Ste5 PF11610.8 CEP07980.1 - 0.046 13.6 0.5 0.098 12.5 0.5 1.5 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region Binary_toxB PF03495.14 CEP07980.1 - 0.093 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Peptidase_M24 PF00557.24 CEP07981.1 - 6.7e-45 153.4 0.0 8.7e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEP07981.1 - 8.7e-15 54.5 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RRF PF01765.19 CEP07982.1 - 3.9e-50 170.0 6.9 3.9e-50 170.0 6.9 1.4 2 0 0 2 2 2 1 Ribosome recycling factor ApoL PF05461.11 CEP07982.1 - 0.0019 17.6 5.2 0.0044 16.4 0.5 2.1 2 0 0 2 2 2 1 Apolipoprotein L HTH_WhiA PF02650.14 CEP07982.1 - 0.015 15.7 1.5 0.092 13.1 0.0 2.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Adaptin_binding PF10199.9 CEP07982.1 - 0.047 14.3 4.5 0.1 13.2 0.5 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 AAA_23 PF13476.6 CEP07982.1 - 0.12 12.9 6.1 2.5 8.5 0.3 2.1 2 0 0 2 2 2 0 AAA domain GlutR_dimer PF00745.20 CEP07982.1 - 0.15 12.5 3.7 3.1 8.3 1.7 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain AcylCoA_dehyd_C PF12186.8 CEP07982.1 - 0.51 10.5 3.7 0.26 11.4 0.8 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF4094 PF13334.6 CEP07982.1 - 0.59 10.6 6.4 7.6 7.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF883 PF05957.13 CEP07982.1 - 0.89 10.2 7.7 0.22 12.1 2.6 2.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CRAL_TRIO PF00650.20 CEP07983.1 - 2.5e-30 105.3 0.1 4.3e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEP07983.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Cyclin PF08613.11 CEP07984.1 - 0.0021 18.4 0.0 0.0021 18.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP07984.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DPBB_1 PF03330.18 CEP07985.1 - 1e-11 45.0 0.1 1e-11 45.0 0.1 2.1 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEP07985.1 - 3.3e-08 33.4 1.5 5.9e-08 32.6 0.0 1.9 1 1 0 2 2 2 1 Barwin family Fungus-induced PF10917.8 CEP07985.1 - 0.0092 16.3 0.5 0.019 15.3 0.0 1.8 2 0 0 2 2 1 1 Fungus-induced protein DUF2909 PF11137.8 CEP07985.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DUF2981 PF11200.8 CEP07985.1 - 0.27 10.9 1.9 0.32 10.7 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Pro-rich PF15240.6 CEP07985.1 - 0.35 11.1 7.6 2.8 8.2 7.6 2.1 1 1 0 1 1 1 0 Proline-rich Conotoxin PF02950.17 CEP07985.1 - 0.57 11.2 0.0 0.57 11.2 0.0 2.9 2 1 1 3 3 3 0 Conotoxin SOG2 PF10428.9 CEP07985.1 - 0.64 9.2 20.5 0.75 8.9 20.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CEP07985.1 - 0.86 8.3 9.4 0.94 8.2 9.4 1.2 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CEP07985.1 - 0.87 7.9 2.7 1.1 7.6 2.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF572 PF04502.13 CEP07985.1 - 0.88 9.1 16.4 1.3 8.6 16.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF5427 PF10310.9 CEP07985.1 - 1.7 7.6 14.4 1.9 7.4 14.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dicty_REP PF05086.12 CEP07985.1 - 3.4 5.5 11.9 3.9 5.3 11.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SWIRM-assoc_2 PF16496.5 CEP07985.1 - 4.5 6.1 11.2 5.3 5.8 11.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4834 PF16118.5 CEP07985.1 - 5.6 8.0 13.9 2.4e+02 2.8 13.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 CEP07985.1 - 6.2 5.4 12.2 6.6 5.3 12.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NPR3 PF03666.13 CEP07985.1 - 6.6 5.4 13.2 8.7 5.0 13.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Miga PF10265.9 CEP07985.1 - 7.2 5.5 10.7 9.2 5.1 10.7 1.1 1 0 0 1 1 1 0 Mitoguardin Peptidase_S49_N PF08496.10 CEP07985.1 - 8.4 6.4 12.1 15 5.6 12.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal zf-C2H2_11 PF16622.5 CEP07986.1 - 0.022 14.5 0.6 0.032 14.0 0.6 1.3 1 0 0 1 1 1 0 zinc-finger C2H2-type Aa_trans PF01490.18 CEP07987.1 - 9.8e-59 199.1 29.8 1.3e-58 198.7 29.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HMG_box PF00505.19 CEP07987.1 - 7.7e-23 80.7 1.4 1.9e-22 79.5 1.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP07987.1 - 1.4e-12 48.0 1.4 1.4e-12 48.0 1.4 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 CEP07987.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain CbtB PF09489.10 CEP07987.1 - 2.7 8.2 7.2 46 4.2 1.1 3.7 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) COX6C PF02937.15 CEP07987.1 - 4 7.6 5.1 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc XPC-binding PF09280.11 CEP07988.1 - 0.096 12.4 1.2 0.15 11.8 0.8 1.5 2 0 0 2 2 2 0 XPC-binding domain TB2_DP1_HVA22 PF03134.19 CEP07989.1 - 1.4e-20 73.0 7.2 2.4e-20 72.2 7.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NIPSNAP PF07978.13 CEP07990.1 - 3.3e-23 81.9 0.1 1.2e-11 44.8 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP Ketoacyl-synt_C PF02801.22 CEP07991.1 - 1.7e-37 128.0 0.2 2.8e-37 127.3 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CEP07991.1 - 2e-32 112.8 1.9 3.8e-32 111.9 0.7 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CEP07991.1 - 6.1e-06 25.8 0.1 1.3e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP07991.1 - 0.00073 19.2 3.4 0.0086 15.7 0.1 3.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain AMP-binding PF00501.28 CEP07992.1 - 1.5e-97 326.9 0.0 1.9e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP07992.1 - 2.8e-13 50.6 0.1 9.4e-13 49.0 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hist_deacetyl PF00850.19 CEP07993.1 - 7.8e-48 163.5 0.0 8.1e-47 160.2 0.0 1.9 1 1 0 1 1 1 1 Histone deacetylase domain bZIP_1 PF00170.21 CEP07994.1 - 3.7e-09 36.5 13.3 4.2e-09 36.4 11.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP07994.1 - 1.1e-06 28.6 10.7 1.1e-06 28.6 10.7 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP07994.1 - 0.0055 17.2 6.5 0.015 15.8 6.5 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor pRN1_helical PF13010.6 CEP07994.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Primase helical domain Mitoc_L55 PF09776.9 CEP07994.1 - 1.2 8.9 5.4 0.67 9.7 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Forkhead PF00250.18 CEP07995.1 - 1.8e-30 105.1 0.1 4.1e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Spt20 PF12090.8 CEP07995.1 - 0.00089 18.9 20.5 0.00089 18.9 20.5 2.5 2 0 0 2 2 2 1 Spt20 family CRT10 PF08728.10 CEP07995.1 - 1.1 7.4 10.2 1.5 6.9 10.2 1.1 1 0 0 1 1 1 0 CRT10 Mito_carr PF00153.27 CEP07996.1 - 1.2e-62 207.9 0.4 2.7e-21 75.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 CEP07997.1 - 3.1e-31 108.9 0.0 1.6e-30 106.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP07997.1 - 9.2e-19 67.6 0.0 7.3e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP07997.1 - 8e-18 65.8 0.0 1.3e-17 65.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CEP07997.1 - 4.2e-07 30.0 0.1 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 CEP07997.1 - 1.1e-06 28.5 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 CEP07997.1 - 1.6e-06 28.1 0.0 6.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.20 CEP07997.1 - 2.7e-05 24.4 0.0 0.00085 19.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 CEP07997.1 - 0.00032 19.5 0.0 0.00076 18.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.25 CEP07997.1 - 0.0013 18.6 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Chlorophyllase2 PF12740.7 CEP07997.1 - 0.0014 17.6 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme UPF0227 PF05728.12 CEP07997.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 CEP07997.1 - 0.0037 17.1 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CEP07997.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 CEP07997.1 - 0.032 13.9 0.0 0.87 9.2 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase BAAT_C PF08840.11 CEP07997.1 - 0.075 12.9 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CEP07997.1 - 0.11 12.3 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase eIF3_subunit PF08597.10 CEP07998.1 - 0.071 13.0 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit HEAT PF02985.22 CEP07999.1 - 2.7e-43 142.3 9.4 0.0011 19.0 0.0 11.1 11 0 0 11 11 11 9 HEAT repeat HEAT_2 PF13646.6 CEP07999.1 - 4.2e-32 110.4 1.8 2.7e-09 37.3 0.0 6.0 2 2 3 5 5 5 5 HEAT repeats Cnd1 PF12717.7 CEP07999.1 - 4.4e-09 36.6 6.1 0.1 12.6 0.1 4.4 2 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEP07999.1 - 2.1e-08 34.6 0.1 0.75 10.4 0.0 5.6 1 1 7 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEP07999.1 - 3.9e-08 33.6 5.3 0.032 14.8 0.3 7.3 6 3 2 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.20 CEP07999.1 - 3.9e-07 29.0 3.0 0.023 13.3 0.0 3.0 2 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 CEP07999.1 - 5.9e-05 22.7 0.9 1.9 8.0 0.0 4.5 2 2 2 4 4 4 1 CLASP N terminal DNA_alkylation PF08713.11 CEP07999.1 - 0.0014 18.3 0.2 0.24 11.1 0.0 3.2 3 1 1 4 4 4 1 DNA alkylation repair enzyme M11L PF11099.8 CEP07999.1 - 0.014 15.7 0.2 5.4 7.3 0.1 3.2 2 1 1 3 3 3 0 Apoptosis regulator M11L like Multi_ubiq PF14452.6 CEP07999.1 - 0.073 13.3 0.1 2.3 8.5 0.1 2.7 2 0 0 2 2 2 0 Multiubiquitin Importin_rep_4 PF18808.1 CEP07999.1 - 0.087 13.1 0.5 3.5 8.0 0.0 3.2 2 1 0 2 2 2 0 Importin repeat HEAT_PBS PF03130.16 CEP07999.1 - 0.15 12.8 0.2 7.1 7.6 0.0 4.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.7 CEP07999.1 - 0.72 10.2 3.3 4 7.8 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RasGAP PF00616.19 CEP08000.1 - 4.2e-47 160.5 0.1 4.2e-47 160.5 0.1 2.6 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEP08000.1 - 1.7e-39 135.1 1.5 1.7e-39 135.1 1.5 2.7 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 CEP08000.1 - 6.3e-15 55.3 0.6 2e-14 53.7 0.1 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 CEP08000.1 - 1.2e-08 33.9 0.8 0.12 12.3 0.0 4.3 4 0 0 4 4 4 3 IQ calmodulin-binding motif Pkinase PF00069.25 CEP08001.1 - 1.1e-70 238.1 0.0 1.4e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08001.1 - 2.8e-30 105.5 0.1 4.2e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP08001.1 - 0.0081 15.1 0.1 0.014 14.4 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain zf-Nse PF11789.8 CEP08001.1 - 0.074 12.9 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ins_beta PF03488.14 CEP08001.1 - 0.3 11.1 2.1 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Sel1 PF08238.12 CEP08002.1 - 1.9e-50 168.1 15.5 5.3e-09 36.5 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat PHD PF00628.29 CEP08006.1 - 0.00046 20.0 11.7 0.00046 20.0 11.7 3.1 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 CEP08006.1 - 0.051 13.5 1.0 0.051 13.5 1.0 4.2 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myosin_head PF00063.21 CEP08007.1 - 5.2e-222 738.8 3.3 6.5e-222 738.5 3.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CEP08007.1 - 3.5e-49 167.0 0.1 7.5e-49 165.9 0.1 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CEP08007.1 - 1.2e-15 56.9 0.6 2.4e-15 55.8 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP08007.1 - 1.4e-12 47.3 0.1 3.5e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP08007.1 - 3.9e-10 39.2 0.1 1e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP08007.1 - 0.00057 20.1 0.4 0.0014 18.9 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.6 CEP08007.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CEP08007.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.12 CEP08007.1 - 0.037 13.6 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 CEP08007.1 - 0.099 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.27 CEP08007.1 - 0.14 12.0 8.4 2.5 8.1 2.1 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif PRK PF00485.18 CEP08007.1 - 0.15 11.8 0.5 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 CEP08007.1 - 0.18 11.7 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 CEP08007.1 - 0.35 10.1 1.3 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin CAF1 PF04857.20 CEP08008.1 - 3.6e-70 236.7 2.4 3.6e-70 236.7 2.4 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease RNase_T PF00929.24 CEP08008.1 - 0.029 14.9 0.3 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 Exonuclease DNA_pol_A_exo1 PF01612.20 CEP08008.1 - 0.14 11.9 0.2 16 5.2 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease Col_cuticle_N PF01484.17 CEP08008.1 - 0.15 12.1 0.0 0.67 10.1 0.1 2.0 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Ribosomal_60s PF00428.19 CEP08008.1 - 0.23 12.1 3.1 1 10.0 2.4 2.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein PALP PF00291.25 CEP08009.1 - 1.2e-60 205.4 0.1 1.4e-60 205.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme pPIWI_RE_REase PF18154.1 CEP08009.1 - 0.04 13.9 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 REase associating with pPIWI_RE BCS1_N PF08740.11 CEP08010.1 - 1.6e-38 132.6 0.1 2.3e-38 132.1 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CEP08010.1 - 2.6e-20 73.2 0.0 5.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CEP08010.1 - 0.0021 17.2 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CEP08010.1 - 0.025 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEP08010.1 - 0.026 14.5 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEP08010.1 - 0.04 14.5 0.1 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEP08010.1 - 0.053 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Adhesin_P1 PF03257.13 CEP08010.1 - 0.068 13.7 0.0 0.31 11.6 0.0 2.1 2 0 0 2 2 2 0 Mycoplasma adhesin P1 AAA_25 PF13481.6 CEP08010.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CEP08010.1 - 0.16 11.8 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DeoC PF01791.9 CEP08011.1 - 1.5e-17 64.0 1.4 2e-17 63.6 1.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 CEP08011.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Lipase_GDSL_3 PF14606.6 CEP08011.1 - 0.065 13.4 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ADK PF00406.22 CEP08012.1 - 6.6e-58 195.1 0.0 7.8e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEP08012.1 - 5e-23 82.0 0.0 1.1e-22 80.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CEP08012.1 - 2.7e-17 62.5 0.0 5.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CEP08012.1 - 8.6e-06 26.3 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CEP08012.1 - 0.0021 18.4 4.4 0.037 14.3 0.2 2.6 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 CEP08012.1 - 0.0022 17.8 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 CEP08012.1 - 0.005 17.0 0.0 0.046 13.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain Methyltransf_28 PF02636.17 CEP08013.1 - 5.9e-36 124.4 0.0 8.8e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 CEP08013.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 CEP08013.1 - 0.048 14.4 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PI3_PI4_kinase PF00454.27 CEP08014.1 - 9.2e-41 140.3 0.0 8.3e-39 133.9 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CEP08014.1 - 1.1e-22 80.4 0.0 3.6e-22 78.7 0.0 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PRP38 PF03371.15 CEP08015.1 - 4.2e-49 166.7 0.3 5.8e-49 166.3 0.3 1.2 1 0 0 1 1 1 1 PRP38 family NOA36 PF06524.12 CEP08015.1 - 0.066 12.5 5.0 0.094 12.0 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein SET PF00856.28 CEP08016.1 - 3.5e-07 30.8 0.0 9.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 SET domain WD40 PF00400.32 CEP08017.1 - 3.1e-65 214.5 21.7 6.7e-11 42.6 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08017.1 - 5.5e-20 71.5 0.6 1e-06 29.0 0.1 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP08017.1 - 1.3e-09 37.3 6.5 0.0062 15.2 0.0 6.1 3 2 3 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CEP08017.1 - 3.7e-06 27.0 0.2 0.16 11.8 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CEP08017.1 - 1.5e-05 24.0 4.7 0.57 8.9 0.0 4.5 2 1 3 5 5 5 3 Nup133 N terminal like DUF4988 PF16378.5 CEP08017.1 - 0.0018 18.0 0.2 6.5 6.4 0.0 3.7 3 1 1 4 4 4 1 Domain of unknown function nos_propeller PF18764.1 CEP08017.1 - 0.004 17.0 0.0 13 5.8 0.0 3.6 3 0 0 3 3 3 1 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 CEP08017.1 - 0.0073 14.9 0.2 1.3 7.5 0.0 3.1 2 1 1 3 3 3 1 Cytochrome D1 heme domain LisH PF08513.11 CEP08017.1 - 0.008 16.1 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 LisH VID27 PF08553.10 CEP08017.1 - 0.04 13.0 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DUF3240 PF11582.8 CEP08017.1 - 0.12 12.5 0.0 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3240) JTB PF05439.12 CEP08018.1 - 7.2e-06 26.0 4.0 0.00055 20.0 4.0 2.2 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) TcpE PF12648.7 CEP08019.1 - 0.81 10.3 4.7 0.57 10.7 0.5 2.1 2 0 0 2 2 2 0 TcpE family T_cell_tran_alt PF15128.6 CEP08019.1 - 0.83 9.5 5.0 0.96 9.3 0.5 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF2839 PF10999.8 CEP08019.1 - 4.1 7.8 13.6 1.4 9.3 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) C2 PF00168.30 CEP08021.1 - 6.8e-08 32.7 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain C2-C2_1 PF11618.8 CEP08021.1 - 4e-07 30.2 0.0 9.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 UBA PF00627.31 CEP08021.1 - 2e-06 27.5 1.1 6.8e-06 25.9 1.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CEP08021.1 - 0.0066 16.2 0.2 0.016 15.0 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain RRM_1 PF00076.22 CEP08022.1 - 6.7e-09 35.4 0.0 1.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T3SS_basalb_I PF17001.5 CEP08022.1 - 0.19 12.3 2.5 1.3 9.7 1.0 2.5 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI RhoGEF PF00621.20 CEP08024.1 - 2.9e-15 57.0 0.1 7.6e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain zf-C2H2_4 PF13894.6 CEP08025.1 - 3.2 8.8 5.7 4.7 8.3 0.9 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Sec2p PF06428.11 CEP08026.1 - 1.5e-12 47.3 15.6 1.5e-12 47.3 15.6 2.6 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.7 CEP08026.1 - 0.0046 17.1 14.5 0.0046 17.1 14.5 1.8 2 0 0 2 2 2 1 Tropomyosin like GAS PF13851.6 CEP08026.1 - 0.0094 15.3 16.0 0.02 14.3 16.0 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 CEP08026.1 - 0.019 15.4 14.2 0.019 15.4 14.2 2.9 2 2 1 3 3 3 0 Centromere protein H (CENP-H) COMM_domain PF07258.14 CEP08026.1 - 0.36 11.0 8.1 9.8 6.4 3.1 2.9 2 0 0 2 2 2 0 COMM domain Cob_adeno_trans PF01923.18 CEP08026.1 - 1.2 9.3 8.0 7.8 6.6 8.0 2.2 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Golgin_A5 PF09787.9 CEP08026.1 - 2.1 7.7 22.9 0.12 11.9 17.1 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 FUSC PF04632.12 CEP08026.1 - 7.1 5.0 8.6 9.5 4.6 8.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family USP8_interact PF08941.10 CEP08026.1 - 9.5 6.0 13.8 7 6.4 4.2 2.9 3 0 0 3 3 3 0 USP8 interacting DUF1772 PF08592.11 CEP08027.1 - 2.9e-18 66.5 0.0 3.7e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) HTH_54 PF18607.1 CEP08027.1 - 0.21 11.7 0.5 14 5.9 0.0 2.1 1 1 1 2 2 2 0 ParA helix turn helix domain UPF0183 PF03676.14 CEP08028.1 - 3.2e-73 247.3 0.4 4.9e-61 207.2 0.1 2.4 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kelch_1 PF01344.25 CEP08028.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif IPK PF03770.16 CEP08029.1 - 8.2e-49 166.1 0.0 1.2e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase RVT_1 PF00078.27 CEP08031.1 - 5.7e-07 29.3 0.1 7.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC1 PF03109.16 CEP08032.1 - 3.2e-20 72.5 0.0 2.7e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family CSN8_PSD8_EIF3K PF10075.9 CEP08033.1 - 3.3e-25 88.8 0.2 4.3e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family ig PF00047.25 CEP08034.1 - 0.032 14.4 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain PHO4 PF01384.20 CEP08035.1 - 6.1e-119 397.0 20.2 7.2e-119 396.8 20.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family Cytochrom_B_C PF00032.17 CEP08035.1 - 0.13 12.6 1.9 2.3 8.5 1.9 2.8 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF5386 PF17360.2 CEP08037.1 - 0.11 12.4 0.1 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5386) Nbl1_Borealin_N PF10444.9 CEP08038.1 - 1.4e-06 27.8 4.2 7.2e-06 25.5 0.3 3.3 3 1 0 3 3 3 1 Nbl1 / Borealin N terminal CSN5_C PF18323.1 CEP08038.1 - 0.85 10.6 10.9 8 7.5 0.2 3.4 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain AMP-binding PF00501.28 CEP08039.1 - 2.2e-95 319.8 0.0 2.8e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP08039.1 - 0.018 16.0 0.0 0.16 12.9 0.0 2.4 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain His_Phos_1 PF00300.22 CEP08040.1 - 4.4e-18 65.7 0.0 1e-17 64.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNase_PH PF01138.21 CEP08041.1 - 1.2e-34 119.7 0.1 1.9e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP08041.1 - 0.0029 17.6 0.2 0.0069 16.4 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Acetyltransf_1 PF00583.25 CEP08043.1 - 8.2e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP08043.1 - 6e-07 29.8 0.2 9.2e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP08043.1 - 0.01 15.8 0.1 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 CEP08043.1 - 0.037 14.2 0.1 0.094 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PTPA PF03095.15 CEP08044.1 - 2.3e-81 273.6 0.4 3.1e-72 243.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Arrestin_N PF00339.29 CEP08044.1 - 8.5e-07 29.1 0.1 2.2e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CEP08044.1 - 0.00012 21.4 0.3 0.00019 20.8 0.3 1.2 1 0 0 1 1 1 1 Rgp1 Methyltransf_25 PF13649.6 CEP08045.1 - 1.1e-15 58.1 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP08045.1 - 2.8e-14 53.2 0.0 2.3e-13 50.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP08045.1 - 1.7e-13 51.0 0.0 3.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP08045.1 - 2.3e-09 37.3 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP08045.1 - 2e-08 33.9 0.0 6.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP08045.1 - 4.4e-07 30.6 0.0 1.3e-06 29.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEP08045.1 - 4.9e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 CEP08045.1 - 0.00049 18.8 0.0 0.0011 17.6 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 CEP08045.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DUF202 PF02656.15 CEP08046.1 - 3e-22 78.8 1.1 5.3e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4732 PF15876.5 CEP08047.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) EF-hand_7 PF13499.6 CEP08048.1 - 2.3e-21 76.0 5.9 8.6e-14 51.8 0.5 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CEP08048.1 - 2e-18 64.5 18.8 1.2e-05 24.5 1.5 4.6 4 1 1 5 5 5 3 EF hand EF-hand_6 PF13405.6 CEP08048.1 - 3.3e-18 64.0 15.1 5.8e-05 22.7 0.7 5.0 3 2 2 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEP08048.1 - 4.3e-15 54.4 13.9 3.2e-05 23.2 1.7 4.4 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 CEP08048.1 - 2.3e-13 49.8 13.8 8.2e-07 28.8 1.8 3.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CEP08048.1 - 1.2e-05 25.2 9.1 0.3 11.0 0.6 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand DUF1707 PF08044.11 CEP08048.1 - 0.021 14.9 0.0 2.8 8.1 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) SPARC_Ca_bdg PF10591.9 CEP08048.1 - 0.071 13.4 1.5 21 5.4 0.1 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CEP08048.1 - 0.1 12.9 2.1 7.8 6.9 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_9 PF14658.6 CEP08048.1 - 0.18 12.2 1.4 14 6.1 0.1 3.2 2 1 0 3 3 3 0 EF-hand domain Ras PF00071.22 CEP08049.1 - 3.7e-48 163.2 0.1 5.8e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08049.1 - 1.7e-14 54.1 0.1 1.3e-13 51.2 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08049.1 - 0.0016 17.9 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP08049.1 - 0.0023 17.5 0.1 0.0048 16.4 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP08049.1 - 0.0089 15.9 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase NPR3 PF03666.13 CEP08050.1 - 1.2e-111 373.8 3.2 1.2e-111 373.8 3.2 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CEP08050.1 - 0.0032 16.3 0.1 0.82 8.4 0.0 2.4 2 0 0 2 2 2 2 Nitrogen permease regulator 2 Glyco_tranf_2_3 PF13641.6 CEP08051.1 - 4.5e-19 69.3 0.4 2.4e-15 57.1 0.5 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 CEP08051.1 - 1.5e-10 40.4 11.2 1.7e-05 23.7 10.2 3.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP08051.1 - 4e-09 36.7 12.0 6.6e-09 36.0 11.6 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP08051.1 - 1.9e-05 24.5 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP08051.1 - 2e-05 24.1 0.3 6.4e-05 22.5 0.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Mss4 PF04421.13 CEP08052.1 - 1.8e-22 79.3 0.0 2.3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Mss4 protein EspB PF05802.11 CEP08053.1 - 0.0019 18.2 3.1 0.0019 18.2 3.1 5.9 1 1 5 6 6 6 1 Enterobacterial EspB protein VitD-bind_III PF09164.10 CEP08053.1 - 0.01 15.8 8.4 20 5.3 0.1 5.8 2 2 4 6 6 6 0 Vitamin D binding protein, domain III DUF883 PF05957.13 CEP08053.1 - 0.017 15.7 4.0 0.017 15.7 4.0 8.2 4 2 3 8 8 8 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CEP08053.1 - 0.092 12.6 61.6 0.012 15.5 16.1 5.1 1 1 3 4 4 4 0 Apolipoprotein A1/A4/E domain DUF2183 PF09949.9 CEP08053.1 - 0.27 11.6 2.9 69 3.9 0.0 3.9 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2183) SHP PF03579.13 CEP08054.1 - 0.012 15.5 0.1 0.012 15.5 0.1 1.8 2 0 0 2 2 2 0 Small hydrophobic protein Big_9 PF17963.1 CEP08055.1 - 0.0028 18.3 0.3 0.0037 18.0 0.3 1.2 1 0 0 1 1 1 1 Bacterial Ig domain CCDC106 PF15794.5 CEP08055.1 - 0.025 14.3 1.2 0.027 14.2 1.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TDRP PF15683.5 CEP08055.1 - 0.16 12.0 1.7 0.17 11.9 1.2 1.4 1 1 0 1 1 1 0 Testis development-related protein DUF515 PF04415.12 CEP08055.1 - 0.21 9.9 5.4 0.25 9.7 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3027 PF11228.8 CEP08056.1 - 0.84 9.6 4.1 2.2 8.3 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) NINJA_B PF16136.5 CEP08056.1 - 1.7 9.1 13.5 1.5 9.2 1.6 3.0 2 0 0 2 2 2 0 Putative nuclear localisation signal LIM_bind PF01803.16 CEP08057.1 - 1.9e-38 132.4 0.0 1.9e-38 132.4 0.0 5.8 3 3 0 3 3 3 1 LIM-domain binding protein Sel1 PF08238.12 CEP08059.1 - 6.5e-36 122.0 21.9 8.4e-09 35.8 0.1 7.4 8 0 0 8 8 8 6 Sel1 repeat TPR_6 PF13174.6 CEP08059.1 - 0.0027 18.2 8.7 0.097 13.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP08059.1 - 0.19 12.0 3.2 2.3 8.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TSC22 PF01166.18 CEP08060.1 - 0.73 10.2 7.5 0.64 10.4 1.3 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family Ntox1 PF15500.6 CEP08060.1 - 2.1 8.8 6.9 0.5 10.7 3.2 1.9 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 PYC_OADA PF02436.18 CEP08060.1 - 3.6 7.3 8.3 16 5.1 8.3 2.1 1 1 0 1 1 1 0 Conserved carboxylase domain DUF4446 PF14584.6 CEP08060.1 - 3.8 7.5 15.6 8.8 6.3 3.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Holin_BhlA PF10960.8 CEP08060.1 - 8.2 6.5 9.3 0.21 11.6 0.6 2.7 1 1 1 2 2 2 0 BhlA holin family LAMTOR5 PF16672.5 CEP08061.1 - 3.7e-17 62.0 0.0 4e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 CEP08061.1 - 0.0022 17.7 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GrpE PF01025.19 CEP08062.1 - 1.2e-44 151.9 2.7 1.6e-44 151.5 2.7 1.1 1 0 0 1 1 1 1 GrpE SF-assemblin PF06705.11 CEP08062.1 - 0.0028 17.0 4.1 0.0032 16.9 2.9 1.5 1 1 1 2 2 2 1 SF-assemblin/beta giardin PRP38 PF03371.15 CEP08062.1 - 0.083 12.7 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 PRP38 family Baculo_PEP_C PF04513.12 CEP08062.1 - 0.43 10.6 3.5 0.67 10.0 1.1 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 CEP08062.1 - 0.69 10.0 6.3 2.5 8.2 2.5 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nramp PF01566.18 CEP08063.1 - 4.8e-91 305.4 24.5 4.5e-46 157.5 7.6 3.0 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein EIIBC-GUT_C PF07663.11 CEP08063.1 - 2 8.6 6.7 0.86 9.8 3.2 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus DHHC PF01529.20 CEP08063.1 - 4.4 7.4 4.9 22 5.1 0.3 2.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase ArfGap PF01412.18 CEP08064.1 - 7.7e-36 122.7 0.1 1.7e-35 121.6 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5600 PF18150.1 CEP08065.1 - 4.7e-39 133.3 1.2 9.8e-39 132.2 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 CEP08065.1 - 2.7e-16 59.4 0.0 1.3e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 CEP08065.1 - 6.1e-14 51.6 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 CEP08065.1 - 2.1e-12 47.5 0.0 1.3e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CEP08065.1 - 1.8e-07 31.2 0.0 5.1e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CEP08065.1 - 8.8e-05 21.8 0.0 0.0003 20.1 0.0 2.0 1 0 0 1 1 1 1 EF hand Gtr1_RagA PF04670.12 CEP08065.1 - 0.00018 20.9 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP08065.1 - 0.00027 20.5 0.0 0.00076 19.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CEP08065.1 - 0.00039 20.6 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 CEP08065.1 - 0.04 13.8 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Ras PF00071.22 CEP08065.1 - 0.086 12.4 0.2 12 5.5 0.1 2.4 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 CEP08065.1 - 0.09 12.2 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 CEP08065.1 - 0.12 12.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Yip1 PF04893.17 CEP08066.1 - 1.2e-18 67.5 12.1 1.7e-18 66.9 12.1 1.1 1 0 0 1 1 1 1 Yip1 domain TRAPP PF04051.16 CEP08067.1 - 7e-38 129.6 0.0 9.3e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Kelch_4 PF13418.6 CEP08068.1 - 6.4e-17 61.3 0.0 3.4e-05 23.7 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP08068.1 - 7.4e-17 61.0 0.2 8.3e-07 29.1 0.0 3.8 1 1 2 3 3 3 3 Kelch motif Kelch_5 PF13854.6 CEP08068.1 - 3.2e-15 55.7 0.0 6.9e-06 25.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CEP08068.1 - 1.1e-13 50.5 0.0 5.3e-05 23.0 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CEP08068.1 - 4.3e-13 49.2 0.2 1.6e-07 31.4 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP08068.1 - 9.8e-07 28.3 0.0 0.048 13.3 0.0 2.7 2 0 0 2 2 2 2 Kelch motif BTB PF00651.31 CEP08068.1 - 2.2e-05 24.7 0.1 6.3e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 BTB/POZ domain DUF2738 PF10927.8 CEP08068.1 - 0.11 11.6 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Pkinase PF00069.25 CEP08069.1 - 1.1e-71 241.3 0.1 1.4e-71 241.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08069.1 - 3.4e-32 111.7 0.0 4.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP08069.1 - 1.6e-07 31.0 0.4 1.8e-05 24.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 CEP08069.1 - 0.00083 19.3 0.1 0.47 10.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP08069.1 - 0.0026 16.8 2.0 0.0047 15.9 2.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEP08069.1 - 0.0048 16.5 3.1 0.033 13.8 3.1 2.0 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CEP08069.1 - 0.036 13.7 1.4 0.55 9.8 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEP08069.1 - 0.066 12.6 0.4 0.14 11.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 CEP08070.1 - 2.2e-07 31.3 0.2 5.6e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CEP08070.1 - 8.8e-06 26.1 0.0 2.8e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain TFIIS_M PF07500.14 CEP08071.1 - 1.2e-24 87.0 0.8 4.6e-24 85.1 0.8 2.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 CEP08071.1 - 1.1e-16 61.1 0.0 2.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 CEP08071.1 - 8.4e-10 38.4 14.3 1.8e-09 37.3 14.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP08071.1 - 0.12 12.0 6.2 0.23 11.1 6.2 1.5 1 0 0 1 1 1 0 PHD-finger IF-2B PF01008.17 CEP08072.1 - 3.2e-71 239.8 2.2 3.8e-71 239.6 2.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.18 CEP08073.1 - 1.7e-07 30.6 0.7 3.6e-07 29.5 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FlxA PF14282.6 CEP08073.1 - 0.024 14.6 5.0 0.05 13.6 5.0 1.5 1 0 0 1 1 1 0 FlxA-like protein MIP-T3_C PF17749.1 CEP08073.1 - 0.15 12.0 2.8 0.33 10.9 2.8 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region OCD_Mu_crystall PF02423.15 CEP08075.1 - 2.7e-54 184.3 2.4 3.2e-54 184.0 2.4 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 CEP08075.1 - 3.1e-07 30.5 0.0 5.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEP08075.1 - 0.021 15.3 0.0 0.073 13.5 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 CEP08075.1 - 0.051 14.4 0.0 0.17 12.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TRIC PF05197.13 CEP08076.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 CEP08076.1 - 0.11 12.5 1.9 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 UPF0126 domain UVR PF02151.19 CEP08077.1 - 0.00095 18.8 11.5 0.0021 17.8 2.8 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif TAN PF11640.8 CEP08077.1 - 0.0026 17.9 0.3 0.0026 17.9 0.3 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair RTP1_C1 PF10363.9 CEP08077.1 - 0.043 14.0 1.7 0.68 10.1 0.5 2.8 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 XAF1_C PF18608.1 CEP08077.1 - 0.051 13.1 7.4 0.17 11.5 0.4 2.6 1 1 1 2 2 2 0 XIAP-associated factor 1 C-terminal domain DUF3253 PF11625.8 CEP08077.1 - 0.067 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) HEAT PF02985.22 CEP08077.1 - 0.15 12.4 0.0 9.9 6.7 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat EMC1_C PF07774.13 CEP08079.1 - 2.5e-71 239.8 0.0 4.2e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CEP08079.1 - 1.9e-09 37.5 0.3 4e-07 29.9 0.2 2.3 2 0 0 2 2 2 2 PQQ-like domain NERD PF08378.11 CEP08079.1 - 0.021 15.3 0.1 0.068 13.6 0.1 1.8 1 0 0 1 1 1 0 Nuclease-related domain Tetraspanin PF00335.20 CEP08080.1 - 8.6e-12 45.3 14.9 1.6e-11 44.3 14.9 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 CEP08080.1 - 0.17 11.6 5.3 1.9 8.2 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Wzy_C PF04932.15 CEP08080.1 - 0.17 11.5 2.9 0.58 9.8 2.9 2.0 1 1 0 1 1 1 0 O-Antigen ligase Kelch_6 PF13964.6 CEP08081.1 - 3.4e-16 58.9 3.3 0.0029 17.8 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CEP08081.1 - 1.4e-15 57.0 2.3 1.2e-05 25.2 0.3 4.0 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP08081.1 - 6e-13 48.2 9.0 2.1e-05 24.3 0.6 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CEP08081.1 - 3.3e-10 39.7 7.3 8.3e-05 22.5 0.3 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CEP08081.1 - 1.8e-09 37.7 1.4 0.015 15.5 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP08081.1 - 0.00014 21.4 17.7 0.54 9.9 0.5 5.6 5 2 0 5 5 5 3 Kelch motif PI3K_1B_p101 PF10486.9 CEP08081.1 - 0.56 7.9 6.4 0.79 7.4 6.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TMEM223 PF14640.6 CEP08083.1 - 9.6e-48 162.5 0.0 1.4e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 223 PhoH PF02562.16 CEP08083.1 - 0.012 15.0 0.0 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein tRNA-synt_2d PF01409.20 CEP08084.1 - 2.5e-51 174.5 1.0 1.7e-29 103.0 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CEP08084.1 - 5e-24 84.6 0.0 1.3e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 CEP08084.1 - 0.0026 16.9 0.1 1.1 8.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) PHD PF00628.29 CEP08085.1 - 8.2e-08 32.0 14.4 1.2e-07 31.5 11.3 2.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CEP08085.1 - 0.00038 20.0 3.0 0.0012 18.3 3.0 1.9 1 0 0 1 1 1 1 PHD-finger zf-met PF12874.7 CEP08085.1 - 0.054 13.9 1.1 0.15 12.5 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sgf11 PF08209.11 CEP08085.1 - 0.56 9.8 10.0 0.11 12.0 0.5 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF2812 PF11193.8 CEP08085.1 - 3.2 8.0 7.6 0.33 11.2 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2812) DEAD PF00270.29 CEP08086.1 - 3.7e-47 160.3 0.1 9.2e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP08086.1 - 2.3e-28 98.7 0.1 7.9e-28 97.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SBF_like PF13593.6 CEP08087.1 - 3.1e-82 276.4 15.3 3.6e-82 276.2 15.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CEP08087.1 - 1.6e-07 31.2 8.1 1.6e-07 31.2 8.1 1.6 2 0 0 2 2 2 1 Sodium Bile acid symporter family FtsX PF02687.21 CEP08087.1 - 0.016 15.7 1.4 0.016 15.7 1.4 3.2 2 2 0 2 2 2 0 FtsX-like permease family Ndc1_Nup PF09531.10 CEP08089.1 - 5 5.7 7.9 5.9 5.5 7.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cactin_mid PF10312.9 CEP08090.1 - 5e-65 218.9 5.5 5e-65 218.9 5.5 2.2 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 CEP08090.1 - 0.012 15.5 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein eIF-5a PF01287.20 CEP08090.1 - 0.077 13.1 3.0 5.5 7.2 0.2 3.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold LRR_9 PF14580.6 CEP08091.1 - 2.4e-60 203.0 5.0 3.1e-60 202.6 5.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CEP08091.1 - 2.4e-07 30.4 10.3 3.7e-07 29.8 6.3 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CEP08091.1 - 1.2e-05 25.5 16.6 0.0015 18.9 5.8 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CEP08091.1 - 0.097 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) muHD PF10291.9 CEP08093.1 - 2.9e-30 105.6 0.6 5.8e-30 104.6 0.6 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CEP08093.1 - 1.9e-11 44.1 0.4 1.5e-10 41.2 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain CHZ PF09649.10 CEP08093.1 - 1.9e-09 36.8 0.0 1.9e-09 36.8 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone domain CHZ CDC45 PF02724.14 CEP08093.1 - 0.016 13.5 17.1 0.029 12.7 17.1 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpb6 PF01192.22 CEP08094.1 - 4.5e-15 55.3 0.4 6.4e-15 54.8 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 CEP08094.1 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Pdase_C33_assoc PF14756.6 CEP08095.1 - 0.049 13.6 0.1 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Peptidase_C33-associated domain EBA-175_VI PF11556.8 CEP08095.1 - 0.05 13.9 0.6 0.085 13.2 0.6 1.3 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 MTHFR PF02219.17 CEP08095.1 - 0.11 11.8 0.8 0.35 10.2 0.1 1.8 1 1 1 2 2 2 0 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.21 CEP08096.1 - 7.2e-43 147.1 0.0 8.8e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2920 PF11144.8 CEP08096.1 - 0.063 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Tagatose_6_P_K PF08013.11 CEP08096.1 - 0.14 10.8 0.1 0.24 10.0 0.1 1.3 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase MOR2-PAG1_C PF14225.6 CEP08096.1 - 0.14 12.0 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Cell morphogenesis C-terminal DUF1206 PF06724.11 CEP08097.1 - 1e-27 96.0 22.4 1.5e-14 53.8 2.7 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) ABC2_membrane_4 PF12730.7 CEP08097.1 - 0.021 14.8 1.8 0.055 13.4 0.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein TNFR_16_TM PF18422.1 CEP08097.1 - 0.022 14.7 1.7 0.022 14.7 1.7 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Abhydrolase_9_N PF15420.6 CEP08097.1 - 0.074 13.0 0.2 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4307 PF14155.6 CEP08097.1 - 0.16 11.8 1.3 6.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) DUF373 PF04123.13 CEP08097.1 - 2.9 7.2 5.3 20 4.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Steroid_dh PF02544.16 CEP08098.1 - 1.2e-33 116.2 5.2 1.2e-33 116.2 5.2 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase RRM_1 PF00076.22 CEP08100.1 - 9.2e-08 31.8 0.7 1.9e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP08100.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF1324 PF07038.11 CEP08101.1 - 0.06 13.6 0.4 0.27 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) Glyco_transf_36 PF06165.11 CEP08101.1 - 0.073 12.5 0.3 0.09 12.2 0.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 36 Tam41_Mmp37 PF09139.11 CEP08102.1 - 3.1e-121 404.8 0.1 5.1e-121 404.0 0.1 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Sin_N PF04801.13 CEP08103.1 - 3.1e-49 168.4 6.1 4e-49 168.0 6.1 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region DUF4482 PF14818.6 CEP08103.1 - 0.27 12.1 7.8 0.084 13.7 4.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) ATP_bind_1 PF03029.17 CEP08104.1 - 1.5e-82 277.0 0.0 1.8e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CEP08104.1 - 4.6e-05 23.3 0.0 7.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 CEP08104.1 - 0.0037 17.4 0.0 0.012 15.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP08104.1 - 0.0087 16.5 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CEP08104.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CEP08104.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CEP08104.1 - 0.02 14.9 0.0 0.026 14.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CEP08104.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CEP08104.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.6 CEP08104.1 - 0.13 12.2 0.0 0.81 9.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 CEP08104.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 CEP08104.1 - 0.2 12.1 0.5 0.61 10.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain Pil1 PF13805.6 CEP08105.1 - 9.1e-29 100.7 7.6 9.1e-29 100.7 7.6 1.8 2 0 0 2 2 2 1 Eisosome component PIL1 CAC1F_C PF16885.5 CEP08105.1 - 0.026 14.2 3.7 0.059 13.0 3.7 1.5 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term TetR_C_29 PF17938.1 CEP08105.1 - 0.1 12.7 0.8 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FMP23 PF17315.2 CEP08105.1 - 0.6 10.3 9.1 1.3 9.2 0.4 2.5 2 1 0 2 2 2 0 Found in mitochondrial proteome DUF2802 PF10975.8 CEP08105.1 - 2.6 8.2 12.1 3.7 7.8 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) FapA PF03961.13 CEP08105.1 - 8.9 4.8 12.0 0.19 10.3 5.1 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A ParD PF09386.10 CEP08107.1 - 2.8e-06 27.6 0.2 0.072 13.5 0.0 3.4 3 0 0 3 3 3 2 Antitoxin ParD GIT_SHD PF08518.11 CEP08107.1 - 0.00053 19.6 2.8 0.074 12.7 0.2 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TENA_THI-4 PF03070.16 CEP08107.1 - 0.0049 16.7 1.8 0.51 10.1 0.2 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family FliS PF02561.14 CEP08107.1 - 0.041 14.1 0.0 4.3 7.6 0.0 2.7 2 0 0 2 2 2 0 Flagellar protein FliS Carbpep_Y_N PF05388.11 CEP08107.1 - 0.057 14.0 0.2 2.5 8.6 0.0 2.8 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide FadA PF09403.10 CEP08107.1 - 0.059 13.9 7.9 0.58 10.7 0.7 2.8 2 1 0 2 2 2 0 Adhesion protein FadA DUF349 PF03993.12 CEP08107.1 - 0.26 11.6 2.1 7.2 7.0 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) RRM_1 PF00076.22 CEP08108.1 - 3.7e-25 87.5 0.1 6.1e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP08108.1 - 7.7e-08 32.0 0.0 0.00062 19.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP08108.1 - 0.00024 20.9 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Pkinase PF00069.25 CEP08109.1 - 1.5e-08 34.3 0.0 4e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08109.1 - 2.8e-05 23.5 0.0 0.00024 20.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase 7TM_GPCR_Srab PF10292.9 CEP08109.1 - 0.041 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Kdo PF06293.14 CEP08109.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Antifungal_prot PF11402.8 CEP08109.1 - 0.5 10.6 5.0 1.1 9.5 5.0 1.6 1 0 0 1 1 1 0 Antifungal protein PI3K_1B_p101 PF10486.9 CEP08110.1 - 0.024 12.5 12.9 0.036 11.8 12.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SCP1201-deam PF14428.6 CEP08110.1 - 0.083 12.8 0.1 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 SCP1.201-like deaminase DUF4637 PF15470.6 CEP08110.1 - 0.59 9.9 11.7 1.7 8.4 11.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 CEP08110.1 - 3 7.1 30.9 3.2 7.0 27.7 2.1 1 1 1 2 2 2 0 BUD22 GREB1 PF15782.5 CEP08110.1 - 4.9 4.1 12.9 7.3 3.6 12.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Astro_capsid_p PF12226.8 CEP08110.1 - 5.4 6.1 13.0 9.6 5.2 13.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LAP1C PF05609.12 CEP08110.1 - 9.4 5.2 17.2 0.29 10.2 10.7 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Gly_transf_sug PF04488.15 CEP08112.1 - 2.9e-05 24.6 0.1 6.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CEP08112.1 - 0.076 12.4 0.6 0.17 11.2 0.6 1.5 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Pkinase PF00069.25 CEP08113.1 - 1.4e-71 241.0 0.0 1.8e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08113.1 - 2.3e-36 125.4 0.0 3.1e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CEP08113.1 - 0.0056 16.3 0.1 0.48 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CEP08113.1 - 0.031 13.2 0.2 0.06 12.3 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CEP08113.1 - 0.045 13.1 0.0 0.087 12.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Sugar_tr PF00083.24 CEP08114.1 - 5e-103 345.4 29.8 5.8e-100 335.3 29.8 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP08114.1 - 5.5e-20 71.6 42.9 1.7e-13 50.2 10.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3054 PF11255.8 CEP08114.1 - 7.6 7.1 14.1 1.2 9.7 8.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) Glyco_hydro_16 PF00722.21 CEP08116.1 - 9.7e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Na_H_Exchanger PF00999.21 CEP08117.1 - 3.2e-51 174.3 45.8 1.7e-50 172.0 46.2 1.7 1 1 1 2 2 2 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 CEP08118.1 - 6e-42 143.8 0.0 8.3e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08118.1 - 4e-24 85.3 0.0 5.1e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEP08118.1 - 0.00041 19.5 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CEP08118.1 - 0.0018 18.3 0.0 0.0045 16.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Asp PF00026.23 CEP08119.1 - 3.8e-18 66.0 0.0 4.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CEP08119.1 - 0.024 15.3 0.0 11 6.8 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease HisG PF01634.18 CEP08120.1 - 2.5e-52 177.1 0.3 3.3e-52 176.7 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CEP08120.1 - 3.5e-24 84.8 0.0 8.1e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 CEP08120.1 - 0.037 14.0 0.2 0.067 13.1 0.2 1.4 1 0 0 1 1 1 0 NMT1/THI5 like WD40 PF00400.32 CEP08121.1 - 5.2e-49 163.2 25.4 8.9e-09 35.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08121.1 - 5.3e-12 45.9 0.8 0.087 13.1 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP08121.1 - 2.2e-05 24.4 0.0 0.00013 21.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEP08121.1 - 0.00016 20.5 9.3 0.0076 14.9 0.3 4.8 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP08121.1 - 0.00056 19.0 0.0 0.37 9.7 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CEP08121.1 - 0.0037 15.8 0.0 2.1 6.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain SH3_1 PF00018.28 CEP08122.1 - 2e-16 59.3 0.0 3.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP08122.1 - 2e-13 49.9 0.0 3.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.13 CEP08122.1 - 3e-13 50.3 3.3 5e-13 49.5 3.3 1.4 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CEP08122.1 - 6.2e-12 45.0 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 CEP08122.1 - 0.14 12.7 0.5 0.72 10.4 0.1 2.0 1 1 1 2 2 2 0 Proline rich region of Caskin proteins adh_short_C2 PF13561.6 CEP08123.1 - 2e-43 148.7 0.4 2.6e-35 122.1 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP08123.1 - 1.2e-42 145.6 0.2 1.1e-27 96.8 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Chromo PF00385.24 CEP08123.1 - 1.4e-16 60.1 1.1 4.5e-16 58.5 1.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KR PF08659.10 CEP08123.1 - 8.9e-05 22.5 0.2 0.0003 20.7 0.1 1.9 2 1 1 3 3 3 1 KR domain Chromo_shadow PF01393.19 CEP08123.1 - 0.00012 22.0 0.5 0.031 14.4 0.1 2.5 2 0 0 2 2 2 1 Chromo shadow domain SOG2 PF10428.9 CEP08123.1 - 0.08 12.1 3.6 0.11 11.7 3.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1776 PF08643.10 CEP08123.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ndc1_Nup PF09531.10 CEP08123.1 - 0.73 8.4 3.0 0.95 8.1 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AT_hook PF02178.19 CEP08123.1 - 1.7 8.8 7.3 0.29 11.1 0.6 2.8 2 0 0 2 2 2 0 AT hook motif PAS PF00989.25 CEP08124.1 - 1.5e-05 25.0 0.0 3.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 CEP08124.1 - 7.1 6.8 7.5 0.32 11.2 1.5 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.18 CEP08125.1 - 9.8e-06 25.8 0.0 1.4e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP08125.1 - 0.013 15.3 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Barwin family Scramblase PF03803.15 CEP08125.1 - 0.079 12.2 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Scramblase Alpha_E3_glycop PF01563.16 CEP08126.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein RNA_pol_inhib PF16857.5 CEP08126.1 - 0.19 11.5 0.0 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase inhibitor DUF1771 PF08590.10 CEP08127.1 - 5.2e-18 65.2 4.9 5.2e-18 65.2 4.9 2.0 2 0 0 2 2 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEP08127.1 - 6.4e-10 39.3 0.1 1.8e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 CEP08127.1 - 9.2e-08 31.9 1.4 9.2e-08 31.9 1.4 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEP08127.1 - 3e-07 30.1 5.5 1.2e-05 25.0 0.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CEP08127.1 - 4.2e-05 23.3 8.5 0.00019 21.2 0.5 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.10 CEP08127.1 - 9.8e-05 22.6 5.7 0.0043 17.3 0.3 2.7 2 0 0 2 2 2 2 HBS1 N-terminus zf-CCCH_2 PF14608.6 CEP08127.1 - 0.0004 20.8 8.4 0.023 15.2 0.3 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEP08127.1 - 0.0024 18.5 0.2 0.0024 18.5 0.2 3.4 2 1 1 3 3 3 2 Torus domain CUE PF02845.16 CEP08127.1 - 0.013 15.2 0.5 0.027 14.2 0.5 1.5 1 0 0 1 1 1 0 CUE domain DMA PF03474.14 CEP08127.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif DUF1296 PF06972.11 CEP08127.1 - 0.033 14.3 0.5 0.082 13.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-CCCH_3 PF15663.5 CEP08127.1 - 0.15 12.2 7.3 1.2e+02 2.9 1.5 2.6 1 1 0 1 1 1 0 Zinc-finger containing family Pkinase PF00069.25 CEP08128.1 - 4.1e-59 200.1 0.0 5.7e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08128.1 - 2.2e-34 118.9 0.0 3.3e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP08128.1 - 5.3e-07 29.2 0.4 1e-06 28.3 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP08128.1 - 1.5e-05 25.1 2.5 0.0021 18.0 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP08128.1 - 1.8e-05 24.2 0.2 5e-05 22.8 0.0 1.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CEP08128.1 - 0.00072 19.2 0.7 0.0012 18.5 0.7 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEP08128.1 - 0.0008 18.5 0.1 0.0016 17.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CEP08128.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CEP08128.1 - 0.055 13.0 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CEP08128.1 - 0.15 10.8 0.2 0.38 9.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SRF-TF PF00319.18 CEP08129.1 - 3.7e-21 74.3 0.1 6.1e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prefoldin PF02996.17 CEP08130.1 - 6.1e-17 61.7 0.1 6.1e-17 61.7 0.1 2.3 2 1 1 3 3 3 1 Prefoldin subunit DUF3835 PF12927.7 CEP08130.1 - 1.1e-13 51.9 0.5 1.1e-13 51.9 0.5 6.7 6 1 1 7 7 7 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 CEP08130.1 - 3.6e-10 39.8 0.1 1.3e-09 38.0 0.1 2.0 1 0 0 1 1 1 1 Prefoldin subunit B56 PF01603.20 CEP08131.1 - 9.5e-191 634.2 5.2 1.3e-190 633.8 5.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SUIM_assoc PF16619.5 CEP08131.1 - 0.0056 16.7 10.0 0.0056 16.7 10.0 3.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Rap_GAP PF02145.15 CEP08133.1 - 3.2e-55 186.6 0.1 1.3e-54 184.6 0.0 2.1 2 0 0 2 2 2 1 Rap/ran-GAP Itfg2 PF15907.5 CEP08133.1 - 1.5 7.8 5.7 2.8 6.9 1.7 2.5 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 RepB-RCR_reg PF10723.9 CEP08133.1 - 3.1 7.8 5.9 0.28 11.2 0.5 2.1 2 0 0 2 2 2 0 Replication regulatory protein RepB Integrase_H2C2 PF17921.1 CEP08134.1 - 9e-08 32.1 1.3 1.9e-07 31.1 0.3 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP08134.1 - 0.099 12.9 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Preseq_ALAS PF09029.10 CEP08134.1 - 8.4 6.9 12.0 0.29 11.6 3.8 2.5 1 1 2 3 3 3 0 5-aminolevulinate synthase presequence UvrD_C PF13361.6 CEP08135.1 - 3.6e-48 164.7 1.3 4.9e-48 164.3 0.2 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CEP08135.1 - 3.8e-21 75.9 1.6 3.4e-09 36.7 0.1 3.5 3 1 1 4 4 4 3 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CEP08135.1 - 2.1e-17 63.8 0.1 3.5e-13 50.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CEP08135.1 - 2.2e-10 40.2 0.0 6.8e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 CEP08135.1 - 2.6e-06 27.2 0.2 0.012 15.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CEP08135.1 - 4.4e-06 26.6 0.2 0.051 13.3 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CEP08135.1 - 0.00032 20.5 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF2183 PF09949.9 CEP08136.1 - 2.1e-32 111.4 1.6 6.1e-32 109.9 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) ATP-grasp_2 PF08442.10 CEP08136.1 - 0.022 14.3 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Zea_mays_MuDR PF05928.11 CEP08136.1 - 0.03 13.9 0.3 0.03 13.9 0.3 1.6 2 0 0 2 2 2 0 Zea mays MURB-like protein (MuDR) Senescence_reg PF04520.13 CEP08136.1 - 0.18 12.6 4.3 0.56 11.0 4.3 1.8 1 0 0 1 1 1 0 Senescence regulator ANAPC_CDC26 PF10471.9 CEP08136.1 - 8.3 7.3 18.0 3.1 8.7 7.6 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Sec62 PF03839.16 CEP08136.1 - 8.4 5.8 7.0 19 4.7 7.0 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Kinesin PF00225.23 CEP08137.1 - 1.5e-105 352.8 6.6 1.5e-105 352.8 6.6 2.6 1 1 2 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP08137.1 - 8.3e-55 184.8 0.3 8.3e-55 184.8 0.3 2.2 2 0 0 2 2 2 1 Microtubule binding Tmemb_cc2 PF10267.9 CEP08137.1 - 0.00088 18.5 24.7 0.00088 18.5 24.7 2.6 1 1 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein MukF_M PF17192.4 CEP08137.1 - 0.0075 16.0 4.0 0.0075 16.0 4.0 2.0 1 1 1 2 2 2 1 MukF middle domain Shugoshin_N PF07558.11 CEP08137.1 - 0.021 14.7 0.3 0.021 14.7 0.3 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Filament PF00038.21 CEP08137.1 - 0.56 9.7 31.3 0.069 12.7 11.5 2.9 1 1 2 3 3 3 0 Intermediate filament protein FUSC PF04632.12 CEP08137.1 - 0.57 8.6 3.6 0.44 9.0 2.3 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 CEP08137.1 - 0.64 10.1 44.0 0.42 10.7 17.4 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 CEP08137.1 - 7.5 6.9 19.1 0.17 12.2 8.2 3.2 1 1 1 2 2 2 0 Tup N-terminal DUF4404 PF14357.6 CEP08137.1 - 8.2 7.1 20.5 6.8 7.4 0.0 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) tRNA-synt_2d PF01409.20 CEP08138.1 - 7.7e-89 297.4 0.1 1.1e-88 296.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CEP08138.1 - 2.1e-21 76.0 0.1 5.4e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CEP08138.1 - 9.8e-07 28.4 0.0 0.0017 17.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CEP08138.1 - 7.3e-05 22.0 0.4 0.0016 17.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 CEP08138.1 - 0.0021 18.0 0.5 0.0051 16.8 0.5 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 2 eIF-3_zeta PF05091.12 CEP08139.1 - 1.7e-192 641.1 2.6 2e-192 640.8 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF16 PF01519.16 CEP08139.1 - 0.022 15.2 0.2 0.94 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 CEP08140.1 - 2.8e-15 56.5 0.2 3.3e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin TMF_TATA_bd PF12325.8 CEP08140.1 - 0.0098 16.1 2.9 0.013 15.7 2.9 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HlyD_2 PF12700.7 CEP08140.1 - 0.053 12.2 1.2 0.06 12.1 1.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF948 PF06103.11 CEP08140.1 - 0.076 13.3 0.5 2.5 8.4 0.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TetR_C_31 PF17940.1 CEP08140.1 - 0.08 13.2 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 CEP08140.1 - 0.12 12.5 1.7 0.3 11.1 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CEP08140.1 - 0.14 12.5 1.3 0.69 10.3 0.1 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Rnk_N PF14760.6 CEP08140.1 - 0.18 12.3 1.6 1.2 9.7 0.3 2.4 2 1 0 2 2 2 0 Rnk N-terminus DivIC PF04977.15 CEP08140.1 - 1.5 8.7 6.4 4.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator GATA PF00320.27 CEP08141.1 - 1.5e-16 59.7 2.2 3e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CEP08141.1 - 1.7e-14 53.3 2.1 3.8e-14 52.2 1.4 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) MCM PF00493.23 CEP08142.1 - 1.2e-98 328.7 0.0 1.8e-98 328.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEP08142.1 - 3.7e-35 120.5 0.4 6.4e-35 119.8 0.4 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEP08142.1 - 1.6e-29 102.1 0.3 3.8e-29 101.0 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEP08142.1 - 1.1e-14 54.8 3.1 2.8e-14 53.6 2.2 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CEP08142.1 - 4.6e-08 33.2 0.0 1.3e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEP08142.1 - 1.4e-06 27.9 0.0 0.0016 17.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEP08142.1 - 0.00023 21.0 0.0 0.02 14.7 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEP08142.1 - 0.00065 19.4 0.0 1.8 8.2 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 CEP08142.1 - 0.00098 19.5 0.2 0.011 16.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain Aconitase PF00330.20 CEP08143.1 - 9.6e-154 512.8 0.0 1.3e-153 512.3 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP08143.1 - 2.7e-41 141.0 0.0 5.5e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CEP08143.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) NDC10_II PF16787.5 CEP08144.1 - 7.5e-05 21.9 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Zwilch PF09817.9 CEP08144.1 - 0.099 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 RZZ complex, subunit zwilch Pkinase PF00069.25 CEP08145.1 - 3.1e-46 157.9 0.0 5.4e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08145.1 - 6.6e-20 71.5 0.0 1.1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP08145.1 - 3.8e-06 27.0 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP08145.1 - 4.8e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP08145.1 - 0.0031 16.5 0.0 0.0071 15.3 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CEP08145.1 - 0.019 14.5 3.9 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase SlyX PF04102.12 CEP08146.1 - 0.063 13.9 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 SlyX Pox_A_type_inc PF04508.12 CEP08146.1 - 0.3 11.0 2.2 0.8 9.7 2.2 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_C12 PF01088.21 CEP08147.1 - 4.2e-51 173.7 0.4 6.2e-51 173.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TOPRIM_C PF16898.5 CEP08147.1 - 0.88 9.9 4.6 0.42 10.9 0.7 2.2 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM DUF872 PF05915.12 CEP08148.1 - 2.5e-15 56.7 0.2 2.9e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Oleosin PF01277.17 CEP08148.1 - 0.049 13.4 1.0 0.066 13.0 1.0 1.1 1 0 0 1 1 1 0 Oleosin Adeno_E3 PF06040.11 CEP08148.1 - 0.16 12.1 0.2 0.16 12.1 0.2 1.9 1 1 1 2 2 2 0 Adenovirus E3 protein Pox_I5 PF04713.12 CEP08148.1 - 1.7 8.7 6.0 5.4 7.1 6.0 1.9 1 1 0 1 1 1 0 Poxvirus protein I5 Hep_59 PF07052.11 CEP08149.1 - 1.5e-32 112.5 0.7 1.5e-32 112.5 0.7 3.6 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 Type_III_YscX PF09474.10 CEP08149.1 - 0.093 13.0 1.2 0.22 11.8 0.2 2.2 2 2 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Methyltransf_32 PF13679.6 CEP08149.1 - 6.8 6.7 7.6 1.3 9.0 0.5 2.7 1 1 1 2 2 2 0 Methyltransferase domain DDE_3 PF13358.6 CEP08150.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3336 PF11815.8 CEP08151.1 - 1e-27 96.5 3.8 2.2e-26 92.2 3.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEP08151.1 - 7.5e-14 52.4 0.1 2.6e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase DUSP PF06337.12 CEP08152.1 - 0.00028 21.4 0.8 0.12 13.0 0.1 2.5 2 0 0 2 2 2 2 DUSP domain F-box PF00646.33 CEP08152.1 - 0.01 15.7 0.3 0.032 14.1 0.3 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 CEP08152.1 - 0.1 12.5 2.8 0.45 10.4 2.8 2.1 1 0 0 1 1 1 0 F-box-like DUF725 PF05267.12 CEP08152.1 - 0.67 9.9 5.9 1.5 8.8 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) DUF3020 PF11223.8 CEP08153.1 - 5.2e-21 74.9 16.1 5.2e-21 74.9 16.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) Pilin_N PF07790.11 CEP08153.1 - 0.2 12.6 1.2 0.47 11.4 0.1 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ATG_C PF09333.11 CEP08154.1 - 5.8e-28 97.1 0.0 2.1e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain zf-CCHC PF00098.23 CEP08154.1 - 7.7e-12 44.7 21.1 0.0043 17.1 1.7 4.4 4 0 0 4 4 4 4 Zinc knuckle Chorein_N PF12624.7 CEP08154.1 - 5.8e-11 42.5 12.6 3.2e-10 40.1 1.8 4.3 3 1 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 CEP08154.1 - 1.1e-10 41.4 0.2 1.1e-10 41.4 0.2 3.6 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 CEP08154.1 - 1.4e-05 25.0 0.0 5.2e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal zf-CCHC_2 PF13696.6 CEP08154.1 - 0.0027 17.5 20.5 0.011 15.5 1.0 3.9 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.6 CEP08154.1 - 0.61 9.9 18.1 1.6 8.5 0.4 4.6 3 1 1 4 4 4 0 Zinc knuckle TIP49 PF06068.13 CEP08155.1 - 4.8e-172 572.0 0.3 5.9e-172 571.7 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CEP08155.1 - 3.9e-23 81.4 0.1 1.2e-22 79.8 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CEP08155.1 - 7.7e-12 45.8 0.1 1.1e-06 29.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEP08155.1 - 7e-10 38.9 0.1 1e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEP08155.1 - 1.5e-05 25.3 0.0 0.025 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP08155.1 - 0.00013 22.4 0.1 0.0064 16.9 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ResIII PF04851.15 CEP08155.1 - 0.0017 18.4 0.1 0.083 12.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 CEP08155.1 - 0.0026 17.2 0.1 0.08 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEP08155.1 - 0.0028 17.6 0.1 0.33 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEP08155.1 - 0.006 16.3 0.0 3.6 7.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 CEP08155.1 - 0.0082 16.2 0.2 1.6 8.8 0.0 3.3 2 1 2 4 4 4 1 AAA domain AAA_19 PF13245.6 CEP08155.1 - 0.014 15.7 3.5 0.13 12.6 2.0 2.6 2 1 0 2 2 1 0 AAA domain DnaB_C PF03796.15 CEP08155.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CEP08155.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP08155.1 - 0.026 14.8 0.0 0.064 13.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 CEP08155.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 CEP08155.1 - 0.071 12.4 0.2 0.18 11.1 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CEP08155.1 - 0.074 12.6 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEP08155.1 - 0.077 13.2 0.0 0.7 10.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 CEP08155.1 - 0.1 12.4 0.3 0.91 9.3 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 CEP08155.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 CEP08155.1 - 0.13 12.7 0.4 1.8 9.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CEP08155.1 - 0.14 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reticulon PF02453.17 CEP08156.1 - 2.6e-28 99.0 7.4 3.4e-28 98.6 7.4 1.1 1 0 0 1 1 1 1 Reticulon YfzA PF14118.6 CEP08156.1 - 0.0077 16.6 0.1 0.0077 16.6 0.1 2.0 2 0 0 2 2 2 1 YfzA-like protein SPC22 PF04573.12 CEP08157.1 - 5.5e-47 159.4 2.5 6.8e-47 159.1 2.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF5126 PF17166.4 CEP08157.1 - 0.071 13.0 0.9 0.13 12.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5126) Sel1 PF08238.12 CEP08158.1 - 5.4e-25 87.3 56.1 0.0026 18.4 0.3 18.9 20 1 0 20 20 20 9 Sel1 repeat APOBEC2 PF18772.1 CEP08158.1 - 0.036 14.1 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 APOBEC2 APOBEC_C PF05240.14 CEP08158.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Pkinase PF00069.25 CEP08159.1 - 6.2e-34 117.6 0.0 2.6e-21 76.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08159.1 - 3e-13 49.6 0.0 7.4e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEP08159.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vps5 PF09325.10 CEP08160.1 - 7e-74 248.3 16.5 7e-74 248.3 16.5 1.8 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CEP08160.1 - 1.8e-24 85.9 0.3 3.9e-22 78.4 0.0 2.6 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 CEP08160.1 - 0.00052 19.6 7.9 0.012 15.1 7.9 2.3 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 CEP08160.1 - 0.03 13.9 12.7 0.12 11.9 12.0 2.3 1 1 0 1 1 1 0 Arfaptin-like domain IMPa_helical PF18642.1 CEP08160.1 - 0.06 13.8 0.5 0.06 13.8 0.5 2.1 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain SLATT_fungal PF18142.1 CEP08160.1 - 0.18 11.8 1.0 0.68 9.9 1.0 2.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain FUSC PF04632.12 CEP08160.1 - 0.18 10.3 0.2 0.26 9.8 0.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glutaredoxin2_C PF04399.13 CEP08160.1 - 0.51 10.2 4.2 0.95 9.3 1.8 2.7 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF948 PF06103.11 CEP08160.1 - 0.71 10.2 5.8 22 5.4 0.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Methyltransf_12 PF08242.12 CEP08160.1 - 1.7 9.4 3.4 3.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain PIG-F PF06699.11 CEP08161.1 - 7e-39 133.8 10.0 8.7e-39 133.5 10.0 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2530 PF10745.9 CEP08161.1 - 1.9 8.8 7.1 0.43 10.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Phage_holin_5_2 PF16079.5 CEP08161.1 - 5.7 7.4 7.3 13 6.2 1.4 3.0 2 2 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Ada3 PF10198.9 CEP08162.1 - 1.5e-31 109.3 1.9 1.5e-31 109.3 1.9 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Herpes_UL56 PF04534.12 CEP08162.1 - 8.3 5.8 7.0 37 3.7 0.0 2.6 2 1 0 3 3 3 0 Herpesvirus UL56 protein Cgr1 PF03879.14 CEP08163.1 - 2.9e-22 79.1 30.4 3.7e-22 78.7 30.4 1.1 1 0 0 1 1 1 1 Cgr1 family DUF936 PF06075.12 CEP08163.1 - 0.017 14.1 11.4 0.017 14.1 11.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) VSG_B PF13206.6 CEP08163.1 - 0.88 8.8 12.9 1 8.5 12.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain HLH PF00010.26 CEP08164.1 - 4.1e-12 45.9 3.9 7e-12 45.1 2.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PhoU_div PF01865.16 CEP08164.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 GTP_EFTU PF00009.27 CEP08165.1 - 3.5e-46 157.2 0.0 5.1e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CEP08165.1 - 7.2e-37 126.7 11.9 1.2e-36 125.9 11.9 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CEP08165.1 - 3.4e-23 81.7 0.0 8.6e-23 80.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CEP08165.1 - 1e-22 80.0 0.0 2.9e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEP08165.1 - 1.7e-10 41.1 0.0 3.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CEP08165.1 - 7e-07 29.2 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CEP08165.1 - 0.00039 20.5 0.2 0.0009 19.3 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CEP08165.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 CEP08165.1 - 0.028 14.0 0.3 0.13 11.8 0.3 2.0 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.23 CEP08165.1 - 0.083 12.9 0.2 1.1 9.3 0.0 2.3 1 1 1 2 2 2 0 Dynamin family F-box PF00646.33 CEP08166.1 - 1.1e-05 25.2 0.0 3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP08166.1 - 0.00047 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CEP08166.1 - 0.34 11.4 9.7 17 6.0 0.1 5.8 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CEP08167.1 - 1.6e-05 24.7 0.1 4.8e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP08167.1 - 7e-05 22.6 0.0 0.0002 21.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF5643 PF18705.1 CEP08167.1 - 0.1 12.6 0.4 0.48 10.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Tubulin PF00091.25 CEP08168.1 - 2.4e-71 240.0 0.0 3.7e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP08168.1 - 4.2e-41 140.1 0.0 6.5e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEP08168.1 - 2.3e-06 27.9 0.0 5.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CEP08168.1 - 0.032 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CEP08168.1 - 0.039 13.1 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Hydrolase_4 PF12146.8 CEP08168.1 - 0.069 12.4 0.0 0.75 9.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase PF00069.25 CEP08169.1 - 8.6e-72 241.7 0.0 1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08169.1 - 7.8e-35 120.4 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP08169.1 - 8.8e-06 25.2 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP08169.1 - 0.065 12.2 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WCCH PF03716.14 CEP08170.1 - 0.0042 16.7 0.6 0.0092 15.6 0.6 1.6 1 0 0 1 1 1 1 WCCH motif PAPA-1 PF04795.12 CEP08171.1 - 8.9e-21 74.5 9.7 8.9e-21 74.5 9.7 2.8 2 1 1 3 3 3 1 PAPA-1-like conserved region zf-HIT PF04438.16 CEP08171.1 - 0.29 11.1 1.7 0.39 10.6 1.7 1.2 1 0 0 1 1 1 0 HIT zinc finger HECT PF00632.25 CEP08172.1 - 3.5e-85 286.2 0.1 3.5e-85 286.2 0.1 2.7 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Pkinase_Tyr PF07714.17 CEP08173.1 - 6.8e-15 55.1 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEP08173.1 - 1.8e-13 50.5 0.0 3.8e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Olduvai PF06758.13 CEP08173.1 - 0.094 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Olduvai domain CENP-I PF07778.11 CEP08174.1 - 8.4e-41 140.2 16.3 1.1e-20 73.8 2.6 2.1 1 1 1 2 2 2 2 Mis6 RdRP PF05183.12 CEP08174.1 - 0.046 12.4 0.8 0.077 11.6 0.8 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase EMP24_GP25L PF01105.24 CEP08175.1 - 1e-46 159.2 1.7 1.8e-46 158.4 1.7 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4381 PF14316.6 CEP08175.1 - 0.053 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EMC3_TMCO1 PF01956.16 CEP08175.1 - 0.17 11.6 1.2 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CarboxypepD_reg PF13620.6 CEP08175.1 - 0.19 12.0 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF16 PF01519.16 CEP08175.1 - 0.37 11.3 5.2 0.49 10.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 NUDIX PF00293.28 CEP08176.1 - 4e-11 43.1 0.1 5.8e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 CEP08176.1 - 0.0077 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4916) DNA_pol_B PF00136.21 CEP08177.1 - 1.1e-104 350.8 0.3 2.9e-104 349.4 0.3 1.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEP08177.1 - 1.9e-29 102.8 0.1 1.2e-28 100.3 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CEP08177.1 - 3.3e-19 69.3 11.3 5.5e-18 65.4 11.8 2.4 1 1 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 CEP08177.1 - 0.0025 16.7 1.1 0.0068 15.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Chitin_synth_2 PF03142.15 CEP08179.1 - 1.3e-227 756.6 3.7 2e-227 756.0 3.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP08179.1 - 5.4e-130 434.7 5.1 7.1e-130 434.3 5.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 CEP08179.1 - 1.8e-21 76.0 1.6 2e-15 56.7 0.1 3.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 CEP08179.1 - 2.6e-13 50.4 0.1 3.7e-12 46.6 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP08179.1 - 5.2e-11 42.8 2.2 5.2e-11 42.8 2.2 2.4 2 1 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP08179.1 - 0.00032 20.6 0.0 0.035 13.9 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2443 PF10398.9 CEP08179.1 - 0.0027 17.7 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2443) Glyco_transf_21 PF13506.6 CEP08179.1 - 0.0063 16.0 0.4 0.042 13.3 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 21 Caskin-tail PF16632.5 CEP08179.1 - 0.028 14.8 0.4 0.076 13.4 0.4 1.7 1 0 0 1 1 1 0 C-terminal region of Caskin AAA_22 PF13401.6 CEP08179.1 - 0.15 12.3 0.1 0.56 10.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CEP08179.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein G_glu_transpept PF01019.21 CEP08180.1 - 8.9e-173 575.7 0.0 1e-172 575.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Nop PF01798.18 CEP08181.1 - 1.8e-90 302.4 0.3 5e-90 301.0 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CEP08181.1 - 1.3e-22 79.9 1.4 1.3e-22 79.9 1.4 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Cdh1_DBD_1 PF18196.1 CEP08181.1 - 0.2 12.0 13.9 0.54 10.6 13.9 1.7 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 GAGA_bind PF06217.12 CEP08181.1 - 0.32 11.3 8.7 0.53 10.5 8.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 CEP08181.1 - 0.51 10.4 27.4 0.78 9.8 27.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 CEP08181.1 - 0.97 9.3 20.8 2.6 7.9 20.8 1.8 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ribosomal_L11_N PF03946.14 CEP08182.1 - 3.9e-24 84.3 0.1 7.5e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEP08182.1 - 4.4e-17 62.4 0.1 7.9e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain tRNA-synt_2b PF00587.25 CEP08184.1 - 8.6e-23 81.2 0.0 4.5e-21 75.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEP08184.1 - 4e-13 49.5 3.3 8.1e-13 48.5 3.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rx_N PF18052.1 CEP08184.1 - 0.061 13.6 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Rx N-terminal domain EamA PF00892.20 CEP08185.1 - 9.1e-09 35.6 13.3 2.2e-07 31.1 8.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family ECF_trnsprt PF12822.7 CEP08185.1 - 0.77 9.8 13.1 2.2 8.4 13.1 1.8 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF2340 PF10209.9 CEP08186.1 - 3.2e-48 163.1 1.7 3.7e-48 162.9 1.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 CEP08186.1 - 0.0099 16.2 0.1 0.012 16.0 0.1 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Ubiquitin_4 PF18036.1 CEP08186.1 - 0.016 15.2 0.6 0.78 9.8 0.6 2.4 1 1 0 1 1 1 0 Ubiquitin-like domain NDT80_PhoG PF05224.12 CEP08187.1 - 7.2e-36 124.1 0.0 7.2e-36 124.1 0.0 3.4 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family TFR_dimer PF04253.15 CEP08188.1 - 1.8e-21 76.5 0.2 5e-21 75.0 0.2 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CEP08188.1 - 8.5e-18 64.8 0.1 1.6e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEP08188.1 - 2.1e-09 37.3 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 PA domain XPG_N PF00752.17 CEP08189.1 - 3.7e-38 130.1 0.1 8.9e-38 128.8 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CEP08189.1 - 1.7e-30 105.2 1.0 4.3e-30 103.9 0.0 2.1 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CEP08189.1 - 5.4e-05 23.7 1.5 0.00017 22.1 0.0 2.5 3 1 1 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CEP08189.1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif F-box-like PF12937.7 CEP08190.1 - 3.9e-05 23.5 0.1 8.6e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP08190.1 - 0.00092 19.0 0.3 0.0026 17.6 0.3 1.8 1 0 0 1 1 1 1 F-box domain ABC_membrane PF00664.23 CEP08191.1 - 4.5e-50 170.8 33.8 4.8e-31 108.4 12.7 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP08191.1 - 1.4e-32 113.1 0.0 5.2e-17 62.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP08191.1 - 9.3e-08 31.8 0.2 0.0007 19.1 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CEP08191.1 - 0.027 14.1 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CEP08191.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP08191.1 - 0.14 12.4 0.3 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.12 CEP08192.1 - 1.4e-119 387.8 54.3 7.9e-11 42.3 0.3 16.1 16 0 0 16 16 16 15 Sel1 repeat TPR_6 PF13174.6 CEP08192.1 - 0.0075 16.8 10.2 7.5 7.4 0.2 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat pP_pnuc_1 PF18165.1 CEP08192.1 - 0.3 11.0 1.0 34 4.3 0.0 4.0 2 1 1 4 4 4 0 Predicted pPIWI-associating nuclease TPR_16 PF13432.6 CEP08192.1 - 0.67 10.7 18.3 0.72 10.6 0.8 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PDCD2_C PF04194.13 CEP08194.1 - 1.9e-37 129.0 0.9 1.9e-37 129.0 0.9 2.8 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 CEP08194.1 - 6.7e-05 22.9 10.7 6.7e-05 22.9 10.7 3.4 3 2 0 3 3 3 1 MYND finger zf-Mss51 PF13824.6 CEP08194.1 - 2.1 8.5 8.3 0.63 10.2 4.1 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Kelch_1 PF01344.25 CEP08195.1 - 3.8e-41 138.4 1.5 7.5e-07 28.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CEP08195.1 - 2.3e-36 123.5 7.4 2.1e-08 34.0 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP08195.1 - 1.6e-35 120.5 5.2 3.8e-06 26.7 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEP08195.1 - 3.1e-33 113.4 12.1 4.6e-06 26.8 0.0 7.9 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP08195.1 - 7.1e-33 111.4 6.5 1.7e-05 24.6 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CEP08195.1 - 1.2e-32 111.0 7.4 8.8e-06 25.8 0.1 6.7 4 2 2 6 6 6 6 Kelch motif TLD PF07534.16 CEP08196.1 - 3.5e-28 98.6 0.7 7.3e-28 97.5 0.7 1.6 1 0 0 1 1 1 1 TLD Lipase_GDSL_2 PF13472.6 CEP08197.1 - 0.00041 20.8 0.1 0.00068 20.1 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Tab2_like PF06485.11 CEP08197.1 - 0.047 13.2 0.1 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 RNA-binding protein Tab2/Atab2 PEN-2 PF10251.9 CEP08198.1 - 1.6 9.2 5.8 3.4 8.1 5.8 1.6 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Sec5 PF15469.6 CEP08200.1 - 1.8e-52 177.9 1.9 1.8e-52 177.9 1.9 3.7 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.11 CEP08200.1 - 2.1e-06 27.7 0.5 2.1e-06 27.7 0.5 3.5 3 0 0 3 3 3 1 Vps51/Vps67 DUF3961 PF13106.6 CEP08200.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Fib_alpha PF08702.10 CEP08200.1 - 2.7 8.2 15.1 0.3 11.3 1.5 4.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4203 PF13886.6 CEP08201.1 - 6.2e-33 114.2 39.1 7.6e-33 113.9 39.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3040 PF11239.8 CEP08201.1 - 0.014 15.7 0.7 0.014 15.7 0.7 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3040) Zn_clus PF00172.18 CEP08202.1 - 0.00019 21.4 11.2 0.00019 21.4 11.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CEP08202.1 - 0.00063 19.7 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 PAS fold ANAPC3 PF12895.7 CEP08203.1 - 3.7e-20 71.9 15.1 3.6e-14 52.7 1.4 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEP08203.1 - 1.4e-14 53.0 9.5 0.029 14.6 0.4 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08203.1 - 8.1e-13 47.4 14.2 0.0061 16.6 0.0 8.5 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP08203.1 - 1.6e-12 46.7 9.2 0.0027 17.4 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP08203.1 - 1.6e-11 44.3 7.1 0.0022 18.3 0.6 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP08203.1 - 1.2e-10 41.8 4.9 0.016 15.7 0.0 6.4 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP08203.1 - 4.9e-07 30.0 0.2 0.25 12.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP08203.1 - 5.1e-05 23.7 1.8 0.13 12.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP08203.1 - 0.00011 22.7 0.8 0.1 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP08203.1 - 0.00039 20.0 5.7 1 9.1 0.0 5.7 7 0 0 7 7 7 1 TPR repeat TPR_7 PF13176.6 CEP08203.1 - 0.00064 19.6 4.8 15 5.9 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEP08203.1 - 0.0019 18.1 5.2 0.056 13.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP08203.1 - 0.0022 17.8 2.8 6.8 6.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP08203.1 - 0.0036 17.4 2.1 4.9 7.3 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CEP08203.1 - 0.0064 16.8 8.6 2.8 8.5 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 CEP08203.1 - 0.039 14.0 0.7 12 6.1 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 CEP08203.1 - 0.12 11.5 1.9 3.8 6.6 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat EamA PF00892.20 CEP08204.1 - 7.2e-05 23.0 36.2 0.00044 20.4 4.5 2.9 3 0 0 3 3 3 2 EamA-like transporter family CENP-N PF05238.13 CEP08204.1 - 0.19 11.0 0.6 0.27 10.5 0.6 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4260 PF14079.6 CEP08204.1 - 0.72 9.8 11.0 0.051 13.6 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) MFS_1 PF07690.16 CEP08205.1 - 2.2e-22 79.5 52.1 2.2e-22 79.5 52.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEP08205.1 - 3e-09 35.8 26.1 5e-09 35.1 26.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phosphoesterase PF04185.14 CEP08206.1 - 7.4e-32 110.9 8.4 9.2e-31 107.3 3.5 2.9 1 1 1 2 2 2 2 Phosphoesterase family Tim54 PF11711.8 CEP08207.1 - 0.04 12.7 1.6 0.057 12.2 1.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ribosomal_S8 PF00410.19 CEP08208.1 - 8.1e-23 80.8 0.0 9.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Pescadillo_N PF06732.11 CEP08209.1 - 8.3e-124 412.5 3.7 8.3e-124 412.5 3.7 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CEP08209.1 - 7.3e-11 42.3 0.0 3.9e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CEP08209.1 - 4e-07 30.3 0.0 8.7e-06 26.0 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sigma70_ner PF04546.13 CEP08209.1 - 0.69 9.8 12.5 0.5 10.2 4.5 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region Mid1 PF12929.7 CEP08210.1 - 1.6e-90 304.4 14.1 9e-90 301.9 14.1 1.9 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CEP08210.1 - 1.5e-05 25.6 5.5 0.0031 18.1 1.5 2.8 2 0 0 2 2 2 2 Fz domain DUF5102 PF17104.5 CEP08210.1 - 0.023 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) PsbT PF01405.17 CEP08210.1 - 0.95 9.3 2.4 1.9 8.4 2.4 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Actin PF00022.19 CEP08211.1 - 1.4e-132 442.2 0.0 5.4e-132 440.2 0.0 1.7 1 1 0 1 1 1 1 Actin MscS_porin PF12795.7 CEP08212.1 - 0.0023 17.5 3.5 0.005 16.4 3.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Herpes_UL6 PF01763.16 CEP08212.1 - 0.0034 16.0 2.4 0.0034 16.0 2.4 1.5 2 0 0 2 2 2 1 Herpesvirus UL6 like Exonuc_VII_L PF02601.15 CEP08212.1 - 0.22 11.1 3.3 0.12 11.9 1.0 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit RPW8 PF05659.11 CEP08212.1 - 0.43 10.3 2.6 0.46 10.2 0.4 2.3 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IFT57 PF10498.9 CEP08212.1 - 1.6 7.6 10.1 0.16 10.9 4.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NDC10_II PF16787.5 CEP08213.1 - 1.7e-08 33.9 0.0 3.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 LAG1-DNAbind PF09271.11 CEP08215.1 - 7.5e-23 81.8 7.5 6.5e-13 49.6 0.3 2.6 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 CEP08215.1 - 2.5e-22 79.7 0.0 6.9e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain TSA PF03249.13 CEP08215.1 - 1.1 8.0 3.5 1.8 7.2 3.5 1.2 1 0 0 1 1 1 0 Type specific antigen TFIIA PF03153.13 CEP08215.1 - 4.4 7.2 13.6 9.5 6.1 13.6 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 CEP08215.1 - 8.6 6.5 17.3 0.069 13.2 4.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sec7 PF01369.20 CEP08216.1 - 2.5e-20 72.9 0.4 3.6e-20 72.4 0.4 1.3 1 0 0 1 1 1 1 Sec7 domain ORF11CD3 PF10549.9 CEP08217.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ORF11CD3 domain Sugar_tr PF00083.24 CEP08218.1 - 1.1e-95 321.2 18.8 1.3e-95 321.0 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP08218.1 - 3.2e-30 105.3 30.2 6.9e-21 74.6 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEP08218.1 - 0.00018 20.1 4.5 0.00033 19.2 4.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.15 CEP08218.1 - 0.13 12.1 4.1 0.16 11.8 1.2 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain MFS_4 PF06779.14 CEP08218.1 - 1.2 8.4 22.9 0.4 9.9 8.3 2.7 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB RRM_1 PF00076.22 CEP08219.1 - 1.7e-31 107.9 4.8 3.8e-15 55.5 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CEP08219.1 - 0.087 12.6 0.0 0.087 12.6 0.0 3.3 2 1 0 3 3 3 0 Rrp7 RRM-like N-terminal domain SR-25 PF10500.9 CEP08219.1 - 0.12 12.0 31.6 0.21 11.2 31.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 CEP08219.1 - 9.4 4.8 11.5 11 4.6 11.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cullin PF00888.22 CEP08220.1 - 2e-184 614.7 22.8 3.4e-184 613.9 22.8 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEP08220.1 - 9.6e-27 92.8 4.6 2.9e-26 91.3 3.3 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain A_deaminase PF00962.22 CEP08221.1 - 2.4e-123 411.7 0.0 3.1e-123 411.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Clathrin PF00637.20 CEP08221.1 - 0.042 13.7 1.8 4.1 7.3 0.1 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS NAD_binding_10 PF13460.6 CEP08222.1 - 1.1e-16 61.3 0.0 1.6e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP08222.1 - 2e-13 50.5 0.0 2.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CEP08222.1 - 2.4e-12 46.8 0.1 5.5e-12 45.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP08222.1 - 1.2e-11 44.2 0.3 1.8e-11 43.6 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CEP08222.1 - 4.8e-08 32.5 0.1 0.0026 16.9 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 CEP08222.1 - 2.8e-07 30.9 0.1 1.6e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 CEP08222.1 - 1.3e-05 24.7 0.0 6.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CEP08222.1 - 2.2e-05 24.0 0.1 0.00012 21.7 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CEP08222.1 - 3.3e-05 23.2 0.1 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein adh_short_C2 PF13561.6 CEP08222.1 - 0.00097 18.7 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CEP08222.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 CEP08222.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 CEP08222.1 - 0.076 12.9 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 KR domain SERTA PF06031.13 CEP08223.1 - 0.021 14.5 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 SERTA motif zf-A20 PF01754.16 CEP08224.1 - 4.2e-09 36.2 9.9 9.6e-09 35.0 9.9 1.7 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 CEP08224.1 - 6.7e-07 29.4 11.2 6.7e-07 29.4 11.2 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger DUF5338 PF17273.2 CEP08224.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Cyclin PF08613.11 CEP08225.1 - 1.3e-13 51.6 4.0 3.1e-13 50.4 0.2 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP08225.1 - 1.3e-05 24.9 2.2 1.8e-05 24.5 0.1 2.2 3 0 0 3 3 3 1 Cyclin, N-terminal domain MCR_alpha PF02249.17 CEP08225.1 - 0.047 14.1 0.1 0.089 13.2 0.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Phage_B PF02304.15 CEP08225.1 - 0.096 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Scaffold protein B Syntaxin PF00804.25 CEP08226.1 - 9.9e-35 120.0 16.7 4.7e-31 108.0 8.1 2.4 2 0 0 2 2 2 2 Syntaxin DUF4988 PF16378.5 CEP08226.1 - 0.0095 15.6 3.2 0.76 9.4 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF4094 PF13334.6 CEP08226.1 - 0.025 15.0 0.7 0.025 15.0 0.7 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4094) SNARE PF05739.19 CEP08226.1 - 0.032 14.2 0.7 0.032 14.2 0.7 2.6 2 0 0 2 2 2 0 SNARE domain DUF1759 PF03564.15 CEP08226.1 - 2.1 8.3 8.7 0.58 10.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) RPA43_OB PF17875.1 CEP08226.1 - 4.6 7.9 9.2 0.89 10.2 4.4 2.2 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I FAM178 PF14816.6 CEP08227.1 - 6.6e-11 41.8 1.5 6.6e-11 41.8 1.5 2.0 1 1 1 2 2 2 1 Family of unknown function, FAM178 DUF5364 PF17322.2 CEP08227.1 - 0.0087 16.4 7.9 0.016 15.6 7.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5364) POP1 PF06978.11 CEP08227.1 - 0.074 13.0 2.6 0.15 12.0 2.6 1.6 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Coagulin PF02035.15 CEP08227.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Coagulin Ras PF00071.22 CEP08228.1 - 3.7e-45 153.4 0.1 4.8e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08228.1 - 1.7e-28 99.3 0.2 3.1e-28 98.4 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08228.1 - 9.8e-12 44.7 0.1 1.2e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP08228.1 - 4e-08 32.9 0.2 5.1e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP08228.1 - 0.00044 20.3 0.3 0.00072 19.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 CEP08228.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CEP08228.1 - 0.0056 16.5 0.0 0.26 11.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CEP08228.1 - 0.008 15.9 0.1 0.34 10.6 0.0 2.6 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CEP08228.1 - 0.0093 15.4 0.7 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TsaE PF02367.17 CEP08228.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 CEP08228.1 - 0.038 13.4 0.0 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CEP08228.1 - 0.061 12.5 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEP08228.1 - 0.076 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP08228.1 - 0.078 12.9 0.0 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CEP08228.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CEP08228.1 - 0.15 12.5 0.0 0.62 10.5 0.0 2.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEP08229.1 - 5.7e-54 182.9 0.6 8.9e-54 182.3 0.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CEP08229.1 - 7.9e-20 71.6 0.0 1.5e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SPRY PF00622.28 CEP08229.1 - 3.2e-18 66.0 0.3 5.6e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 SPRY domain DUF815 PF05673.13 CEP08229.1 - 0.00061 19.0 0.0 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CEP08229.1 - 0.0037 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CEP08229.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEP08229.1 - 0.0076 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CEP08229.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CEP08229.1 - 0.019 15.4 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 CEP08229.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CEP08229.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEP08229.1 - 0.034 14.1 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CEP08229.1 - 0.038 14.5 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CEP08229.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CEP08229.1 - 0.047 13.4 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEP08229.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CEP08229.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.15 CEP08229.1 - 0.21 11.5 0.0 0.72 9.7 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain UTP15_C PF09384.10 CEP08230.1 - 1.1e-47 161.4 1.4 1.8e-47 160.7 1.4 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CEP08230.1 - 2.4e-25 88.3 6.4 1.5e-06 28.8 0.1 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08230.1 - 2.4e-10 40.6 0.1 0.00076 19.7 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CEP08230.1 - 5.1e-05 23.3 0.1 0.19 11.7 0.0 3.0 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ECH_1 PF00378.20 CEP08231.1 - 2e-48 164.9 0.0 2.8e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP08231.1 - 1.1e-29 104.1 0.0 1.3e-26 93.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-UBR PF02207.20 CEP08232.1 - 1.4e-19 70.0 12.3 1.4e-19 70.0 12.3 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CEP08232.1 - 4.2e-10 39.3 1.7 9.9e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS DUF1764 PF08576.10 CEP08233.1 - 2.3e-17 63.7 29.2 1.1e-16 61.5 7.4 3.3 1 1 3 4 4 4 2 Eukaryotic protein of unknown function (DUF1764) DUF3391 PF11871.8 CEP08233.1 - 0.03 14.9 6.1 0.05 14.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TMEM51 PF15345.6 CEP08233.1 - 0.26 11.1 5.3 0.45 10.3 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 RIFIN PF02009.16 CEP08233.1 - 0.29 11.0 11.2 0.34 10.8 11.2 1.1 1 0 0 1 1 1 0 Rifin Tfb4 PF03850.14 CEP08233.1 - 0.33 10.4 2.9 0.42 10.1 2.9 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 Protamine_P2 PF00841.19 CEP08233.1 - 0.97 10.0 5.0 0.5 10.9 2.9 1.6 2 0 0 2 2 2 0 Sperm histone P2 PBP_sp32 PF07222.12 CEP08233.1 - 2.2 7.7 10.1 3 7.2 10.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 WDCP PF15390.6 CEP08233.1 - 7.1 4.9 8.6 8.1 4.7 8.6 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MFS_1 PF07690.16 CEP08234.1 - 3.2e-36 125.0 30.5 1.2e-35 123.1 30.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CEP08234.1 - 0.08 11.2 11.6 0.0076 14.6 3.5 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Man-6-P_recep PF02157.15 CEP08234.1 - 0.11 11.6 0.4 0.24 10.4 0.4 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate receptor GRA6 PF05084.13 CEP08234.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Transgly_assoc PF04226.13 CEP08234.1 - 3.2 8.1 9.8 11 6.4 1.0 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein MMS1_N PF10433.9 CEP08235.1 - 5.5e-59 200.1 2.3 5.5e-59 200.1 2.3 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEP08235.1 - 1.1e-18 67.6 0.0 3e-18 66.2 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region WD40 PF00400.32 CEP08236.1 - 5.9e-62 204.1 33.6 3.9e-07 30.6 0.3 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 CEP08236.1 - 3.4e-52 176.1 0.1 5.7e-52 175.4 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CEP08236.1 - 8e-18 64.5 12.6 0.023 15.0 0.0 9.1 3 3 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP08236.1 - 3.9e-06 26.0 14.2 1.3 7.9 0.1 7.0 2 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP08236.1 - 5.6e-06 25.3 18.5 0.66 8.5 0.0 8.2 5 5 3 8 8 8 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP08236.1 - 0.00036 20.0 10.9 0.29 10.4 0.0 6.1 2 2 4 6 6 6 1 WD40-like domain Cytochrom_D1 PF02239.16 CEP08236.1 - 0.00048 18.8 2.7 0.0014 17.2 0.3 2.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain SdiA-regulated PF06977.11 CEP08236.1 - 0.0008 18.7 0.2 0.0033 16.7 0.2 2.1 1 0 0 1 1 1 1 SdiA-regulated Hira PF07569.11 CEP08236.1 - 0.0014 18.4 1.2 6.1 6.5 0.0 5.5 6 1 0 7 7 7 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 CEP08236.1 - 0.0037 16.1 2.3 5 5.8 0.0 5.0 4 2 0 4 4 4 1 Nup133 N terminal like VID27 PF08553.10 CEP08236.1 - 0.0054 15.8 0.9 0.89 8.5 0.0 3.0 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain Utp12 PF04003.12 CEP08236.1 - 0.034 14.5 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF745 PF05335.13 CEP08237.1 - 0.083 12.6 4.0 0.11 12.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0449 PF15136.6 CEP08237.1 - 0.22 12.0 8.7 0.26 11.8 3.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Sec34 PF04136.15 CEP08237.1 - 1.5 8.7 7.8 2.6 7.9 0.3 2.1 1 1 1 2 2 2 0 Sec34-like family DUF4140 PF13600.6 CEP08237.1 - 5.7 7.4 10.0 3 8.3 0.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 CEP08237.1 - 8.5 6.9 16.4 1 9.9 8.7 2.0 1 1 0 2 2 2 0 Apg6 coiled-coil region Pho88 PF10032.9 CEP08238.1 - 1.7e-50 170.8 0.0 2.8e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.32 CEP08238.1 - 2.7e-27 94.4 11.5 0.00024 21.8 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08238.1 - 4.5e-21 75.0 2.1 0.00033 20.9 0.0 6.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP08238.1 - 1.5e-09 38.0 0.8 7e-05 22.8 0.1 3.9 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CEP08238.1 - 7.1e-05 22.6 0.0 0.026 14.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 CEP08238.1 - 0.00038 19.6 0.3 0.0016 17.5 0.4 1.9 1 1 1 2 2 2 1 Coatomer WD associated region Nup160 PF11715.8 CEP08238.1 - 0.00066 18.4 2.1 0.21 10.2 0.3 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP08238.1 - 0.00069 19.0 0.3 3.1 7.0 0.0 3.7 3 1 0 3 3 3 2 WD40-like domain VID27 PF08553.10 CEP08238.1 - 0.048 12.7 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 CEP08238.1 - 0.16 10.2 0.0 1.1 7.4 0.0 1.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Alk_phosphatase PF00245.20 CEP08239.1 - 2.1e-60 204.9 0.1 5.9e-60 203.4 0.1 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 CEP08239.1 - 3e-05 23.6 4.6 0.00011 21.7 0.3 3.0 3 1 0 3 3 3 1 Sulfatase Phosphodiest PF01663.22 CEP08239.1 - 0.00048 19.8 0.1 0.00095 18.8 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSP70 PF00012.20 CEP08240.1 - 3.5e-262 870.9 8.2 4e-262 870.8 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP08240.1 - 7.7e-17 61.1 0.1 1e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEP08240.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CEP08240.1 - 0.011 15.0 0.2 0.031 13.5 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 CEP08240.1 - 0.041 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein HOIP-UBA PF16678.5 CEP08240.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.8 4 0 0 4 4 4 0 HOIP UBA domain pair Sigma70_ner PF04546.13 CEP08241.1 - 0.003 17.5 3.6 0.0042 17.0 3.6 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region RRN3 PF05327.11 CEP08241.1 - 0.24 9.9 2.1 0.26 9.8 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 CEP08241.1 - 0.91 8.8 16.9 1.2 8.4 16.9 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CEP08241.1 - 2.1 8.4 6.9 3.3 7.7 6.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 CEP08241.1 - 2.5 8.5 13.9 3.7 8.0 13.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 CEP08241.1 - 3.5 6.7 19.0 4.6 6.3 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 CEP08241.1 - 5.1 7.1 10.5 7.9 6.5 10.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 CEP08241.1 - 7.3 4.6 15.2 9.3 4.2 15.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CEP08241.1 - 7.9 6.1 6.8 11 5.6 6.8 1.3 1 0 0 1 1 1 0 FAM176 family Pro_Al_protease PF02983.14 CEP08242.1 - 0.46 10.6 3.8 0.79 9.8 2.3 2.2 1 1 1 2 2 2 0 Alpha-lytic protease prodomain MFS_1 PF07690.16 CEP08244.1 - 8.9e-39 133.4 25.1 8.9e-39 133.4 25.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CEP08244.1 - 3.7e-05 23.2 2.0 3.7e-05 23.2 2.0 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB BolA PF01722.18 CEP08245.1 - 5.1e-14 52.3 0.0 1.3e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF2415 PF10313.9 CEP08246.1 - 9.1e-10 38.3 0.0 5.7e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 CEP08246.1 - 1.2e-09 38.3 0.0 0.00012 22.3 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP08246.1 - 6.1e-06 26.9 0.0 0.15 13.0 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Lgl_C PF08596.10 CEP08246.1 - 0.0065 15.2 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Coatomer_WDAD PF04053.14 CEP08246.1 - 0.0081 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region Ge1_WD40 PF16529.5 CEP08246.1 - 0.018 14.0 0.0 0.43 9.5 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peripla_BP_1 PF00532.21 CEP08246.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family PglZ PF08665.12 CEP08246.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 PglZ domain DUF3767 PF12597.8 CEP08249.1 - 0.14 12.0 0.3 0.74 9.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) TT_ORF1 PF02956.14 CEP08252.1 - 0.048 12.3 9.4 0.06 12.0 9.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 UPF0524 PF15823.5 CEP08252.1 - 0.094 12.1 4.3 0.11 11.8 4.3 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 ABC2_membrane_3 PF12698.7 CEP08252.1 - 4.1 6.4 6.9 4.2 6.4 6.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PMSI1 PF15322.6 CEP08252.1 - 6.2 6.2 10.3 6.7 6.1 10.3 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative WD40 PF00400.32 CEP08254.1 - 6.5e-19 67.9 9.4 3.4e-07 30.8 0.0 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08254.1 - 0.00054 20.2 1.2 4.9 7.5 0.1 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NDUFB10 PF10249.9 CEP08255.1 - 6.7e-11 42.8 0.9 7.8e-11 42.6 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Alpha_L_fucos PF01120.17 CEP08256.1 - 1.7e-89 300.7 1.1 3.5e-89 299.7 1.1 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 CEP08256.1 - 0.00026 21.5 0.0 0.001 19.6 0.0 2.0 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 CEP08256.1 - 0.071 13.3 0.4 1.3 9.1 0.0 2.9 4 0 0 4 4 4 0 Hypothetical glycosyl hydrolase 6 TFIIB PF00382.19 CEP08257.1 - 1.3e-36 124.4 0.8 1.8e-19 69.6 0.0 3.2 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CEP08257.1 - 3.5e-22 78.6 1.9 3.5e-22 78.6 1.9 3.5 4 0 0 4 4 4 1 Brf1-like TBP-binding domain HSP70 PF00012.20 CEP08258.1 - 2.1e-05 22.9 0.2 3.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP08258.1 - 0.0061 15.4 0.5 0.011 14.5 0.5 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 CEP08259.1 - 3.8e-31 108.1 0.1 6e-30 104.2 0.1 2.3 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 CEP08259.1 - 8e-20 71.3 0.8 2.3e-08 33.6 0.1 3.4 3 0 0 3 3 3 3 Putative actin-like family MreB_Mbl PF06723.13 CEP08259.1 - 1.3e-05 24.2 0.0 0.00047 19.1 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CEP08259.1 - 0.00058 20.2 0.2 0.002 18.5 0.2 2.1 1 1 0 1 1 1 1 Cell division protein FtsA SOBP PF15279.6 CEP08259.1 - 0.32 11.5 7.4 0.54 10.8 7.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CENP-F_leu_zip PF10473.9 CEP08260.1 - 1.8e-05 24.8 1.7 3.9e-05 23.7 1.7 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCPsignal PF00015.21 CEP08260.1 - 0.007 16.2 1.6 0.052 13.4 0.2 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin_1 PF12718.7 CEP08260.1 - 0.0088 16.2 9.4 0.018 15.2 9.4 1.5 1 0 0 1 1 1 1 Tropomyosin like Fzo_mitofusin PF04799.13 CEP08260.1 - 0.011 15.3 6.2 0.024 14.2 6.2 1.5 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 CEP08260.1 - 0.012 14.8 2.7 0.02 14.2 2.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 CEP08260.1 - 0.015 14.2 5.9 0.029 13.2 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein FPP PF05911.11 CEP08260.1 - 0.025 12.8 9.3 0.0099 14.1 6.9 1.4 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil FlxA PF14282.6 CEP08260.1 - 0.031 14.3 13.8 0.066 13.2 13.8 1.5 1 0 0 1 1 1 0 FlxA-like protein UpxZ PF06603.11 CEP08260.1 - 0.046 14.0 0.5 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists KxDL PF10241.9 CEP08260.1 - 0.075 13.3 9.5 0.38 11.0 8.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein IFT57 PF10498.9 CEP08260.1 - 0.28 10.1 9.8 0.55 9.2 9.8 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1980 PF09323.10 CEP08260.1 - 0.3 11.0 3.5 0.59 10.0 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Mto2_bdg PF12808.7 CEP08260.1 - 0.37 11.1 6.3 0.86 9.9 6.3 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3450 PF11932.8 CEP08260.1 - 0.48 9.7 9.2 0.57 9.4 6.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 CEP08260.1 - 0.49 9.9 5.7 0.25 10.9 2.4 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4570 PF15134.6 CEP08260.1 - 0.66 10.0 13.4 14 5.7 11.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF1664 PF07889.12 CEP08260.1 - 0.66 10.0 3.9 0.69 10.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 CEP08260.1 - 0.87 9.5 4.0 1.6 8.7 2.4 2.3 1 1 0 1 1 1 0 Sec20 Lipoprotein_20 PF13942.6 CEP08260.1 - 1.2 9.0 10.8 1 9.2 8.8 1.9 2 0 0 2 2 2 0 YfhG lipoprotein DUF745 PF05335.13 CEP08260.1 - 2.8 7.6 12.2 0.41 10.3 7.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) THOC7 PF05615.13 CEP08260.1 - 2.9 8.2 15.2 0.46 10.8 10.7 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 Atg14 PF10186.9 CEP08260.1 - 3.7 6.5 10.4 6.1 5.8 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 CEP08260.1 - 6.6 7.1 11.8 2 8.8 8.4 1.8 2 0 0 2 2 2 0 YlqD protein DUF4407 PF14362.6 CEP08260.1 - 8 5.7 8.1 2.7 7.3 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-HC5HC2H_2 PF13832.6 CEP08262.1 - 2.1e-16 60.1 8.9 2.1e-16 60.1 8.9 3.7 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEP08262.1 - 6.9e-12 45.5 3.8 6.9e-12 45.5 3.8 4.6 3 2 1 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.18 CEP08262.1 - 1.1e-10 41.4 0.1 2.7e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 CEP08262.1 - 1.5e-09 37.6 29.5 1.1e-07 31.6 14.6 5.5 7 1 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 CEP08262.1 - 1.3e-07 31.0 4.4 1.3e-07 31.0 4.4 5.4 6 0 0 6 6 6 2 PHD-finger GATA PF00320.27 CEP08262.1 - 0.00025 20.6 0.8 0.00025 20.6 0.8 3.6 2 1 0 2 2 2 1 GATA zinc finger ELM2 PF01448.24 CEP08262.1 - 0.00098 19.8 0.0 0.0062 17.3 0.0 2.5 1 1 0 1 1 1 1 ELM2 domain Lon_C PF05362.13 CEP08265.1 - 9.8e-71 237.5 0.0 1.9e-70 236.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CEP08265.1 - 1.9e-33 116.1 0.9 1.9e-33 116.1 0.9 2.2 2 1 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CEP08265.1 - 4.7e-23 82.1 0.0 1.3e-22 80.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEP08265.1 - 5.7e-07 29.6 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEP08265.1 - 1.8e-05 24.9 0.0 5.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 CEP08265.1 - 3.4e-05 23.7 0.0 8.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 CEP08265.1 - 3.5e-05 23.6 0.0 0.00048 19.9 0.0 2.9 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 CEP08265.1 - 7.1e-05 21.9 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 CEP08265.1 - 0.00014 22.2 0.1 0.002 18.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP08265.1 - 0.00052 20.6 0.2 0.028 15.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP08265.1 - 0.00056 20.3 0.1 0.0025 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CEP08265.1 - 0.0045 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CEP08265.1 - 0.008 16.1 0.4 0.33 10.8 0.0 2.9 2 1 1 3 3 3 1 NTPase SKI PF01202.22 CEP08265.1 - 0.022 14.9 0.2 0.21 11.7 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase ClpB_D2-small PF10431.9 CEP08265.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.9 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein AAA_30 PF13604.6 CEP08265.1 - 0.054 13.2 2.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CEP08265.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEP08265.1 - 0.078 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CEP08265.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DNTTIP1_dimer PF18192.1 CEP08265.1 - 0.15 12.4 3.9 3 8.3 0.1 3.6 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain Exo_endo_phos PF03372.23 CEP08267.1 - 8e-19 68.1 0.2 2.2e-17 63.3 0.1 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CEP08267.1 - 9.7e-13 48.0 2.9 2.7e-12 46.6 2.9 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CEP08267.1 - 0.00044 20.1 0.0 0.0094 15.8 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase UPF0193 PF05250.11 CEP08267.1 - 0.43 10.3 8.1 0.87 9.3 8.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0193) NAM-associated PF14303.6 CEP08267.1 - 1.6 9.4 11.9 3.2 8.5 11.9 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pkinase PF00069.25 CEP08268.1 - 2.3e-60 204.2 0.0 3.5e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08268.1 - 2.3e-38 132.0 0.0 8.1e-38 130.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP08268.1 - 7.4e-07 28.4 5.4 2.2e-06 26.9 5.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEP08268.1 - 4.3e-06 26.2 0.0 8.1e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CEP08268.1 - 0.00011 21.8 0.1 0.00044 19.9 0.1 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 CEP08268.1 - 0.00076 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP08268.1 - 0.0052 16.4 0.2 0.0092 15.6 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CEP08268.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CGGC PF08821.11 CEP08268.1 - 0.12 12.5 0.5 0.33 11.2 0.5 1.7 1 0 0 1 1 1 0 CGGC domain Pkinase_fungal PF17667.1 CEP08268.1 - 0.14 10.9 1.1 0.22 10.3 1.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase FA_desaturase PF00487.24 CEP08269.1 - 1.3 8.8 11.5 0.14 12.0 7.1 1.6 2 0 0 2 2 2 0 Fatty acid desaturase Whi5 PF08528.11 CEP08270.1 - 0.0026 17.3 0.3 0.0048 16.5 0.3 1.5 1 0 0 1 1 1 1 Whi5 like DUF2250 PF10007.9 CEP08270.1 - 0.13 12.3 6.1 0.23 11.6 5.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) LIDHydrolase PF10230.9 CEP08271.1 - 1.6e-68 231.2 0.2 1.8e-68 231.0 0.2 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CEP08271.1 - 7.6e-07 29.0 0.0 1.3e-05 25.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP08271.1 - 9.5e-07 28.3 0.0 9.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CEP08271.1 - 0.00022 21.0 0.1 0.00036 20.3 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CEP08271.1 - 0.0093 16.6 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 CEP08271.1 - 0.016 14.9 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.25 CEP08271.1 - 0.092 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 CEP08271.1 - 0.11 11.5 0.7 0.29 10.1 0.7 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DnaT PF17948.1 CEP08271.1 - 0.13 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 DnaT DNA-binding domain cobW PF02492.19 CEP08272.1 - 6e-40 136.7 0.8 8.6e-40 136.2 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEP08272.1 - 2.7e-11 43.2 0.0 5.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CEP08272.1 - 0.00048 20.1 0.2 0.47 10.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEP08272.1 - 0.0011 18.4 1.2 0.25 10.8 0.0 2.6 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 CEP08272.1 - 0.002 18.1 0.3 0.0079 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CEP08272.1 - 0.0035 17.1 0.0 0.0097 15.7 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CEP08272.1 - 0.0051 16.8 0.6 0.042 13.8 0.0 2.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CEP08272.1 - 0.0052 17.1 0.3 0.021 15.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CEP08272.1 - 0.04 13.8 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CEP08272.1 - 0.05 14.0 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 CEP08272.1 - 0.051 13.4 0.1 4.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CEP08272.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 CEP08272.1 - 0.074 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CEP08272.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CEP08272.1 - 0.095 13.2 1.6 0.4 11.2 1.6 2.2 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 CEP08272.1 - 0.096 11.8 5.5 0.71 9.0 1.3 2.6 2 1 0 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.6 CEP08272.1 - 0.1 13.1 0.2 0.25 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP08272.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEP08272.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CEP08272.1 - 6 7.3 11.1 37 4.7 11.1 2.2 1 1 0 1 1 1 0 AAA domain NAD_binding_6 PF08030.12 CEP08273.1 - 1.4e-13 51.3 1.5 4.7e-12 46.3 1.5 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CEP08273.1 - 2.5e-13 50.2 12.1 2.5e-13 50.2 12.1 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component PgaD PF13994.6 CEP08273.1 - 0.0018 18.3 0.8 0.0018 18.3 0.8 2.9 2 1 1 3 3 3 2 PgaD-like protein FAD_binding_8 PF08022.12 CEP08273.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 FAD-binding domain NAD_binding_1 PF00175.21 CEP08273.1 - 0.017 15.7 0.0 0.044 14.4 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF3784 PF12650.7 CEP08273.1 - 0.45 10.8 0.0 0.45 10.8 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3784) SDH_alpha PF03313.15 CEP08275.1 - 8.7e-105 350.1 0.2 1.2e-104 349.6 0.2 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CEP08275.1 - 7.3e-58 195.3 0.1 1.8e-57 194.1 0.1 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain Glyco_hydro_10 PF00331.20 CEP08275.1 - 0.0036 16.5 0.4 0.015 14.5 0.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 10 Phosphodiest PF01663.22 CEP08276.1 - 8.6e-83 278.9 3.0 1.1e-82 278.5 3.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CEP08276.1 - 3.9e-07 29.8 1.3 8.8e-05 22.0 1.3 2.8 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CEP08276.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 CEP08276.1 - 0.077 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PglZ domain PC-Esterase PF13839.6 CEP08277.1 - 8.7e-27 94.6 0.6 1.7e-26 93.6 0.0 1.7 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 CEP08277.1 - 0.083 13.2 4.0 0.24 11.7 4.0 1.8 1 0 0 1 1 1 0 PMR5 N terminal Domain HrpB4 PF09502.10 CEP08278.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB4) Solute_trans_a PF03619.16 CEP08279.1 - 3.4e-89 298.9 19.5 4.2e-89 298.6 19.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyoxal_oxid_N PF07250.11 CEP08280.1 - 3.4e-55 186.9 0.0 1.1e-54 185.2 0.0 1.8 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CEP08280.1 - 6e-22 77.8 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 CEP08280.1 - 0.0063 16.5 0.8 15 5.7 0.0 4.4 4 1 1 5 5 5 2 Galactose oxidase, central domain Fasciclin PF02469.22 CEP08281.1 - 1.5e-27 96.3 0.3 1.6e-12 47.8 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain Rax2 PF12768.7 CEP08282.1 - 0.01 15.3 0.2 0.035 13.5 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SKG6 PF08693.10 CEP08282.1 - 0.014 14.8 0.2 0.1 12.0 0.0 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TFIIA PF03153.13 CEP08282.1 - 0.023 14.7 11.6 0.04 13.9 11.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 CEP08282.1 - 0.11 12.1 17.3 0.17 11.4 17.3 1.4 1 0 0 1 1 1 0 PPP4R2 TIMELESS_C PF05029.13 CEP08282.1 - 0.26 10.4 9.1 0.32 10.1 9.1 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region VTC PF09359.10 CEP08283.1 - 8.9e-41 140.1 5.8 8.9e-41 140.1 5.8 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 CEP08283.1 - 1.4e-11 44.6 3.8 1.4e-11 44.6 3.8 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP08283.1 - 4.8e-05 23.5 21.9 9.9e-05 22.4 0.4 3.6 3 1 1 4 4 4 2 SPX domain Mit_KHE1 PF10173.9 CEP08283.1 - 0.041 14.0 0.2 0.1 12.7 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related VTC PF09359.10 CEP08284.1 - 1.9e-83 280.1 0.3 3e-83 279.4 0.3 1.3 1 0 0 1 1 1 1 VTC domain Foie-gras_1 PF11817.8 CEP08284.1 - 5.5e-45 154.0 0.1 1.1e-42 146.4 0.1 2.6 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 CEP08284.1 - 4.6e-38 131.4 0.0 4.9e-37 128.0 0.0 2.0 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi SPX PF03105.19 CEP08284.1 - 1e-11 45.5 2.6 0.00012 22.1 0.6 3.0 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.15 CEP08284.1 - 1.7e-10 41.2 1.8 3.3e-10 40.3 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Gryzun-like PF12742.7 CEP08284.1 - 1.6e-05 24.8 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF4707 PF15806.5 CEP08284.1 - 0.00071 18.6 0.0 0.0019 17.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4707) BatD PF13584.6 CEP08284.1 - 0.00092 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Oxygen tolerance TPR_12 PF13424.6 CEP08284.1 - 0.024 14.9 0.2 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08284.1 - 0.23 11.7 0.6 3 8.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat dsDNA_bind PF01984.20 CEP08286.1 - 4.7e-34 117.0 4.1 5.4e-34 116.8 4.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TPR_20 PF14561.6 CEP08286.1 - 0.049 14.0 2.0 0.079 13.3 2.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-1_beta_acid PF10587.9 CEP08286.1 - 0.11 13.0 1.0 0.11 13.0 1.0 2.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Astro_capsid_p PF12226.8 CEP08288.1 - 7.5 5.6 9.6 11 5.1 9.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein UpxZ PF06603.11 CEP08289.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists MFS_1_like PF12832.7 CEP08290.1 - 2.3e-47 161.7 25.5 5.5e-32 111.1 9.4 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 CEP08290.1 - 1.3e-13 50.7 45.9 4.3e-08 32.5 26.0 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CEP08290.1 - 9.8e-06 24.8 12.8 9.8e-06 24.8 12.8 2.4 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 CEP08290.1 - 6.8 5.3 25.8 0.072 11.9 7.3 2.3 2 1 0 2 2 2 0 LacY proton/sugar symporter Arm-DNA-bind_4 PF14657.6 CEP08293.1 - 0.32 10.8 1.9 0.85 9.4 1.9 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain RhoGAP PF00620.27 CEP08294.1 - 3.1e-36 124.5 0.0 5.5e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Colipase PF01114.18 CEP08294.1 - 0.091 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Colipase, N-terminal domain EF-hand_7 PF13499.6 CEP08295.1 - 1e-12 48.3 1.5 6.4e-12 45.8 1.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEP08295.1 - 1.3e-08 34.1 1.5 1.1e-05 25.0 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEP08295.1 - 1.3e-08 33.8 1.1 0.00039 19.8 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CEP08295.1 - 5.2e-07 28.9 0.1 0.023 14.2 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CEP08295.1 - 3.2e-05 23.7 2.9 0.13 12.1 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEP08295.1 - 0.0051 17.1 0.2 0.032 14.5 0.2 2.0 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Sigma54_CBD PF04963.13 CEP08295.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain ELO PF01151.18 CEP08296.1 - 6.7e-55 186.3 29.4 8.2e-55 186.0 29.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FAM165 PF14981.6 CEP08296.1 - 0.43 10.4 5.1 1.8 8.4 2.0 2.6 2 0 0 2 2 2 0 FAM165 family PC-Esterase PF13839.6 CEP08297.1 - 5.4e-09 36.2 0.1 7.9e-07 29.1 0.0 2.8 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Acyltransferase PF01553.21 CEP08298.1 - 1.7e-35 121.6 0.1 2.5e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase YlaH PF14036.6 CEP08298.1 - 0.013 15.8 0.6 0.032 14.5 0.6 1.6 1 0 0 1 1 1 0 YlaH-like protein P34-Arc PF04045.14 CEP08299.1 - 2.5e-106 354.8 2.1 4.1e-106 354.1 2.1 1.3 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc NDK PF00334.19 CEP08299.1 - 6.7e-23 81.2 0.0 1.5e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF667 PF05018.13 CEP08300.1 - 1.5e-82 275.9 0.0 1.7e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 CEP08301.1 - 1.1e-41 143.0 0.1 1.2e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08301.1 - 3.6e-13 49.4 0.1 2e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 CEP08301.1 - 0.055 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Wbp11 PF09429.10 CEP08301.1 - 0.084 13.3 10.4 0.038 14.4 5.9 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 CAP59_mtransfer PF11735.8 CEP08301.1 - 0.17 11.6 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MRP-63 PF14978.6 CEP08301.1 - 0.28 11.8 2.9 0.16 12.6 0.6 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 DUF3818 PF12825.7 CEP08302.1 - 6.1e-92 308.2 1.2 1.1e-91 307.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CEP08302.1 - 1.4e-16 60.7 1.3 4.2e-16 59.1 1.3 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.24 CEP08302.1 - 3.2e-13 49.6 0.3 8.4e-13 48.3 0.1 1.9 2 0 0 2 2 2 1 PX domain HTH_23 PF13384.6 CEP08303.1 - 1.3e-05 24.9 0.2 3e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Myb_DNA-bind_6 PF13921.6 CEP08303.1 - 2.7e-05 24.3 0.2 9.2e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain EFTUD2 PF16004.5 CEP08303.1 - 0.0017 18.9 1.6 0.0026 18.4 1.6 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Myb_DNA-binding PF00249.31 CEP08303.1 - 0.0096 16.1 0.9 0.0096 16.1 0.9 2.4 3 1 0 3 3 3 1 Myb-like DNA-binding domain HTH_29 PF13551.6 CEP08303.1 - 0.075 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Rap1_C PF11626.8 CEP08303.1 - 0.18 11.9 0.8 0.26 11.4 0.7 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_28 PF13518.6 CEP08303.1 - 0.45 10.7 2.1 0.6 10.3 0.5 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain PBP1_TM PF14812.6 CEP08303.1 - 0.82 10.1 4.4 2 8.8 4.3 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC50 PF03381.15 CEP08304.1 - 1.1e-88 297.5 0.1 1.3e-88 297.2 0.1 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RGS PF00615.19 CEP08305.1 - 6e-16 58.8 6.3 8.8e-16 58.2 5.3 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 CEP08305.1 - 2.3e-07 30.7 0.6 3.9e-07 30.0 0.6 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain RICTOR_N PF14664.6 CEP08307.1 - 0.004 16.2 0.1 0.0062 15.6 0.1 1.1 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term MMS22L_C PF14911.6 CEP08307.1 - 0.035 13.2 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Drf_GBD PF06371.13 CEP08307.1 - 0.043 13.4 0.6 0.07 12.7 0.6 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain RGS PF00615.19 CEP08307.1 - 0.11 12.7 0.0 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 Regulator of G protein signaling domain JmjC PF02373.22 CEP08308.1 - 2.5e-16 60.1 1.1 5.8e-16 58.9 0.7 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CEP08308.1 - 1.4e-14 54.4 1.3 1.9e-14 54.0 1.3 1.3 1 0 0 1 1 1 1 Cupin-like domain GPI PF06560.11 CEP08308.1 - 0.04 13.2 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) SpoU_methylase PF00588.19 CEP08309.1 - 6.3e-23 81.5 0.0 1.4e-22 80.4 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family SRF-TF PF00319.18 CEP08310.1 - 6.2e-22 76.8 0.1 9.7e-22 76.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SNF5 PF04855.12 CEP08311.1 - 1.1e-50 172.6 9.7 4.8e-26 92.0 0.4 2.8 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 HA2 PF04408.23 CEP08311.1 - 4.7e-24 84.8 0.0 4.7e-24 84.8 0.0 3.4 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP08311.1 - 3.1e-15 56.5 0.0 9.7e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEP08311.1 - 3e-13 49.9 0.0 8.5e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CEP08311.1 - 6.1e-09 35.9 0.4 1.4e-08 34.8 0.4 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP08311.1 - 0.00017 21.8 0.1 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEP08311.1 - 0.0021 18.4 0.3 0.0047 17.3 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP08311.1 - 0.0053 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEP08311.1 - 0.0054 16.1 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 CEP08311.1 - 0.0086 16.1 3.1 3.1 7.8 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CEP08311.1 - 0.023 14.6 0.1 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain Kinesin PF00225.23 CEP08311.1 - 0.025 13.5 0.7 0.047 12.6 0.7 1.3 1 0 0 1 1 1 0 Kinesin motor domain T2SSE PF00437.20 CEP08311.1 - 0.031 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Herpes_ori_bp PF02399.15 CEP08311.1 - 0.048 11.7 0.0 0.077 11.0 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_24 PF13479.6 CEP08311.1 - 0.058 13.1 0.9 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEP08311.1 - 0.085 13.4 2.6 0.5 10.9 0.3 2.9 2 1 0 2 2 1 0 ABC transporter PhoH PF02562.16 CEP08311.1 - 0.097 12.1 0.1 0.27 10.7 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 CEP08311.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 CEP08311.1 - 0.25 10.6 0.0 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DNA_pol_phi PF04931.13 CEP08311.1 - 0.33 9.0 4.5 0.58 8.2 4.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L32e PF01655.18 CEP08312.1 - 3.8e-49 165.6 0.5 4.6e-49 165.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Pro_isomerase PF00160.21 CEP08313.1 - 1.9e-41 142.0 0.5 2.5e-41 141.6 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone PF00125.24 CEP08314.1 - 5.8e-17 62.3 0.0 7.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CEP08314.1 - 7.5e-12 44.8 0.8 1.6e-11 43.7 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CEP08314.1 - 0.00019 21.6 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.21 CEP08315.1 - 1.6e-242 806.6 0.4 2e-242 806.3 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CEP08315.1 - 1.5e-47 161.7 0.5 2.4e-47 161.0 0.5 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CEP08315.1 - 4.6e-14 51.8 0.3 9.5e-14 50.7 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP08315.1 - 1.2e-11 44.2 0.1 3.3e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP08315.1 - 2.6e-11 43.0 0.0 7.2e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP08315.1 - 0.0011 19.3 0.3 0.0011 19.3 0.3 2.0 2 0 0 2 2 1 1 Bacterial SH3 domain AAA_22 PF13401.6 CEP08315.1 - 0.017 15.4 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 CEP08315.1 - 0.042 13.4 0.2 6.6 6.2 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Phostensin_N PF13916.6 CEP08315.1 - 0.11 12.9 0.7 0.36 11.2 0.7 1.9 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal AAA_16 PF13191.6 CEP08315.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FGGY_N PF00370.21 CEP08315.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain NACHT PF05729.12 CEP08315.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.27 CEP08315.1 - 0.65 9.9 10.0 1.2 9.1 0.9 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif Zds_C PF08632.10 CEP08316.1 - 1e-23 82.8 2.1 1.9e-23 82.0 2.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term ACOX PF01756.19 CEP08317.1 - 2.1e-32 112.1 0.1 6.2e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CEP08317.1 - 8.6e-16 57.9 0.3 1.7e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CEP08317.1 - 2.8e-15 57.0 0.1 7.4e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Spidroin_N PF16763.5 CEP08317.1 - 0.099 12.7 0.1 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term Acyl-CoA_dh_1 PF00441.24 CEP08317.1 - 0.11 12.7 0.6 0.62 10.3 0.0 2.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.15 CEP08318.1 - 3.2e-148 495.1 50.2 7.1e-148 494.0 50.2 1.5 1 1 0 1 1 1 1 OPT oligopeptide transporter protein ABC_membrane PF00664.23 CEP08319.1 - 7.6e-38 130.7 5.3 1e-37 130.3 5.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEP08319.1 - 2.3e-36 125.3 0.0 6.4e-36 123.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CEP08319.1 - 4.2e-05 23.1 0.1 0.00056 19.4 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEP08319.1 - 0.00038 20.9 0.0 0.0014 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CEP08319.1 - 0.0007 20.0 0.1 0.02 15.3 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEP08319.1 - 0.0013 19.0 0.1 0.013 15.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEP08319.1 - 0.0015 18.5 0.0 0.067 13.2 0.0 2.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 CEP08319.1 - 0.018 14.9 0.1 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 CEP08319.1 - 0.026 14.6 0.0 0.22 11.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain TOPRIM_C PF16898.5 CEP08319.1 - 0.035 14.4 0.4 0.093 13.0 0.4 1.6 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM AAA_29 PF13555.6 CEP08319.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CEP08319.1 - 0.056 13.7 0.5 2.8 8.2 0.0 2.7 2 1 0 3 3 2 0 AAA domain Rad17 PF03215.15 CEP08319.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 CEP08319.1 - 0.059 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 CEP08319.1 - 0.086 13.1 0.3 0.66 10.2 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 CEP08319.1 - 0.14 12.3 0.1 0.75 9.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CEP08319.1 - 0.16 11.6 0.2 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PTPlike_phytase PF14566.6 CEP08320.1 - 3.4e-117 387.8 3.1 5e-43 146.9 0.0 4.5 3 1 1 4 4 4 4 Inositol hexakisphosphate DSPc PF00782.20 CEP08320.1 - 0.00053 19.8 0.0 0.0096 15.7 0.0 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP08320.1 - 0.013 15.1 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase MAAL_C PF07476.11 CEP08320.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Cyclin_N PF00134.23 CEP08321.1 - 0.0045 16.7 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain HBD PF18534.1 CEP08321.1 - 0.0062 16.6 0.1 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 Helical bundle domain SPX PF03105.19 CEP08321.1 - 0.24 11.3 7.0 0.36 10.7 7.0 1.2 1 0 0 1 1 1 0 SPX domain Cyclin PF08613.11 CEP08321.1 - 0.44 10.9 0.1 0.44 10.9 0.1 3.0 1 1 1 2 2 2 0 Cyclin Lipase_GDSL_2 PF13472.6 CEP08322.1 - 0.0039 17.6 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEP08322.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase THRAP3_BCLAF1 PF15440.6 CEP08323.1 - 0.038 13.0 5.6 0.046 12.7 5.6 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SUIM_assoc PF16619.5 CEP08323.1 - 0.97 9.5 13.3 1.4 9.0 13.2 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CEP08323.1 - 4.6 6.8 15.5 0.51 9.9 11.3 1.5 2 0 0 2 2 2 0 Spt20 family Methyltransf_16 PF10294.9 CEP08324.1 - 2.6e-32 112.0 0.5 2.9e-30 105.3 0.5 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CEP08324.1 - 0.0026 18.4 0.0 0.0067 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP08324.1 - 0.0058 16.5 0.1 0.0082 16.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP08324.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP08324.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 CEP08324.1 - 0.037 14.8 0.1 0.082 13.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.15 CEP08324.1 - 0.04 13.6 0.0 0.083 12.6 0.0 1.6 1 1 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 CEP08324.1 - 0.04 13.3 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 CEP08324.1 - 0.086 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GFO_IDH_MocA_C PF02894.17 CEP08324.1 - 0.13 12.3 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans PF04082.18 CEP08325.1 - 3.4e-27 95.1 2.7 6.5e-27 94.2 0.2 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP08325.1 - 4.5e-09 36.3 12.1 9.2e-09 35.3 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 CEP08325.1 - 0.15 12.2 0.1 0.37 11.0 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF5318 PF17249.2 CEP08326.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) TFIIF_alpha PF05793.12 CEP08326.1 - 7.5 5.0 14.4 15 4.1 14.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GARS_A PF01071.19 CEP08327.1 - 2.7e-83 278.5 0.0 5e-83 277.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 CEP08327.1 - 5.2e-35 120.9 0.0 1.2e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 CEP08327.1 - 4.1e-34 117.2 0.1 1.3e-33 115.6 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 CEP08327.1 - 5.6e-30 103.5 0.9 1.2e-29 102.3 0.9 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CEP08327.1 - 2.9e-14 53.5 0.6 2.8e-13 50.3 0.5 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 CEP08327.1 - 0.00018 21.2 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CEP08327.1 - 0.00031 20.3 0.4 0.00074 19.1 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CEP08327.1 - 0.0055 16.8 0.0 0.019 15.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CEP08327.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 CEP08327.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_4 PF13535.6 CEP08327.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ING PF12998.7 CEP08329.1 - 1.1e-20 74.1 0.7 3.3e-20 72.6 0.7 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Fungal_trans PF04082.18 CEP08329.1 - 5.2e-07 29.0 1.6 1.1e-06 27.9 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.29 CEP08329.1 - 0.00038 20.3 6.7 0.00092 19.1 6.7 1.7 1 0 0 1 1 1 1 PHD-finger DUF3325 PF11804.8 CEP08329.1 - 0.02 15.1 0.1 0.049 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF4407 PF14362.6 CEP08329.1 - 0.042 13.2 4.4 0.074 12.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-HC5HC2H PF13771.6 CEP08329.1 - 0.091 13.0 1.2 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain GUB_WAK_bind PF13947.6 CEP08329.1 - 0.1 13.4 0.1 0.43 11.3 0.1 2.1 1 0 0 1 1 1 0 Wall-associated receptor kinase galacturonan-binding BRE1 PF08647.11 CEP08329.1 - 2.2 8.4 7.5 5.1 7.2 0.1 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase zf-HC5HC2H_2 PF13832.6 CEP08329.1 - 4.6 7.5 8.0 0.83 9.8 0.3 2.8 3 0 0 3 3 3 0 PHD-zinc-finger like domain BCIP PF13862.6 CEP08330.1 - 2.4e-65 220.2 4.4 3.4e-65 219.7 4.4 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 CEP08331.1 - 2.5e-16 59.8 10.3 0.0039 18.0 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.11 CEP08331.1 - 6.3e-05 22.8 0.4 0.00023 21.0 0.2 2.1 2 0 0 2 2 2 1 LisH RNA_pol_I_A49 PF06870.12 CEP08332.1 - 2.7e-98 329.4 4.1 3.2e-98 329.1 4.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_25 PF13649.6 CEP08333.1 - 2.8e-12 47.2 0.0 6.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEP08333.1 - 1.5e-10 41.0 0.1 2.2e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CEP08333.1 - 2.7e-10 40.2 0.1 5.3e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP08333.1 - 1.9e-09 38.1 0.0 4.4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP08333.1 - 2.5e-07 30.7 0.0 8.2e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP08333.1 - 1.2e-05 26.0 0.0 2.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEP08333.1 - 1.3e-05 24.3 0.1 1.5e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CEP08333.1 - 1.8e-05 24.2 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CEP08333.1 - 7.2e-05 22.4 0.2 0.00012 21.6 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CEP08333.1 - 0.00028 20.9 0.3 0.00045 20.2 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CEP08333.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.16 CEP08333.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 CEP08333.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CEP08333.1 - 0.047 13.1 0.8 0.17 11.3 0.8 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 CEP08333.1 - 0.051 14.6 0.0 0.11 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CEP08333.1 - 0.092 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 CEP08333.1 - 0.12 11.9 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 SDF PF00375.18 CEP08334.1 - 3.9e-102 342.2 38.7 4.6e-102 342.0 38.7 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Glyco_trans_2_3 PF13632.6 CEP08336.1 - 6.2e-15 55.6 0.0 6.2e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF2722 PF10846.8 CEP08337.1 - 7.1e-05 21.9 16.9 9.3e-05 21.6 16.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CEP08337.1 - 0.016 15.2 27.0 0.027 14.5 27.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CEP08337.1 - 0.042 12.5 1.7 0.043 12.5 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_clus PF00172.18 CEP08337.1 - 0.068 13.3 2.0 0.13 12.4 2.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Otopetrin PF03189.13 CEP08337.1 - 0.09 11.6 0.8 0.089 11.6 0.8 1.1 1 0 0 1 1 1 0 Otopetrin DUF104 PF01954.16 CEP08337.1 - 0.15 12.5 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 DUF702 PF05142.12 CEP08337.1 - 0.17 12.3 11.2 0.3 11.6 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Zip PF02535.22 CEP08337.1 - 0.29 10.3 3.6 0.37 10.0 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAS PF00989.25 CEP08337.1 - 0.35 10.9 3.5 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 PAS fold Presenilin PF01080.17 CEP08337.1 - 1.1 7.9 15.0 1.7 7.4 15.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 CEP08337.1 - 1.4 8.3 9.2 2.2 7.6 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CobT PF06213.12 CEP08337.1 - 1.5 8.1 16.9 2.3 7.6 16.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TERB2 PF15101.6 CEP08337.1 - 1.7 8.7 16.8 3 7.8 16.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 CEP08337.1 - 1.8 9.2 20.5 0.66 10.6 17.7 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SLC12 PF03522.15 CEP08337.1 - 1.8 7.5 10.8 2.6 7.0 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CTU2 PF10288.9 CEP08337.1 - 1.8 8.8 12.2 3.4 7.9 12.2 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4407 PF14362.6 CEP08337.1 - 3.4 7.0 14.2 4.9 6.4 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 CEP08337.1 - 3.4 6.4 11.8 4.8 5.9 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAT1 PF09770.9 CEP08337.1 - 3.7 5.7 19.2 4.9 5.3 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4834 PF16118.5 CEP08337.1 - 5 8.2 17.7 14 6.7 16.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CEP08337.1 - 5.9 6.4 42.5 1.7 8.2 39.2 1.7 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 CEP08337.1 - 6.8 6.4 11.7 11 5.7 11.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Roughex PF06020.11 CEP08337.1 - 7.1 5.6 11.8 12 4.9 11.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein GREB1 PF15782.5 CEP08337.1 - 9 3.3 11.7 12 2.9 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MutS_V PF00488.21 CEP08338.1 - 1.9e-76 256.3 0.0 3.4e-76 255.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEP08338.1 - 2.7e-35 122.4 5.8 6e-35 121.2 5.8 1.6 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CEP08338.1 - 4.2e-23 81.7 0.0 1.1e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CEP08338.1 - 6.6e-15 55.6 0.0 2.8e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II WD40 PF00400.32 CEP08339.1 - 0.0012 19.6 0.5 7.2 7.7 0.1 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat SGL PF08450.12 CEP08339.1 - 0.0079 15.8 0.0 2.2 7.8 0.0 2.8 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region CENP-F_leu_zip PF10473.9 CEP08340.1 - 2.6e-05 24.2 7.4 2.6e-05 24.2 7.4 3.2 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2407_C PF13373.6 CEP08340.1 - 9.1 6.4 10.1 13 5.9 2.4 2.8 1 1 1 2 2 2 0 DUF2407 C-terminal domain eIF3_subunit PF08597.10 CEP08341.1 - 3.8e-45 154.7 37.7 4.3e-45 154.5 37.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3861 PF12977.7 CEP08341.1 - 0.021 15.0 2.2 0.23 11.7 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Integrin_b_cyt PF08725.11 CEP08341.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.2 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain GST_N_3 PF13417.6 CEP08342.1 - 1.2e-20 73.7 0.0 2.8e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP08342.1 - 8.1e-17 61.3 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP08342.1 - 2.2e-16 60.0 0.8 2.6e-15 56.5 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 CEP08342.1 - 8.3e-10 39.2 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP08342.1 - 1.3e-08 34.9 0.1 3.3e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP08342.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP08342.1 - 0.00012 22.2 0.1 0.00027 21.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CEP08342.1 - 0.005 17.0 0.0 0.0097 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 CEP08342.1 - 0.0068 17.1 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain DNTTIP1_dimer PF18192.1 CEP08342.1 - 0.044 14.1 0.4 0.091 13.1 0.4 1.4 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain Trehalase PF01204.18 CEP08343.1 - 9.5e-176 585.6 0.9 1.2e-175 585.3 0.9 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CEP08343.1 - 4.5e-15 55.0 2.3 4.5e-15 55.0 2.3 2.4 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain F-box-like PF12937.7 CEP08344.1 - 1.9e-06 27.7 0.4 7e-06 25.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like CSTF1_dimer PF16699.5 CEP08344.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain F-box-like PF12937.7 CEP08345.1 - 5.5e-06 26.2 1.1 2.3e-05 24.2 0.5 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 CEP08346.1 - 2.2e-07 30.7 1.0 5.2e-07 29.5 1.0 1.7 1 0 0 1 1 1 1 F-box-like Ran_BP1 PF00638.18 CEP08347.1 - 9.5e-16 58.2 0.4 9.5e-16 58.2 0.4 2.4 2 1 0 2 2 2 1 RanBP1 domain DUF2428 PF10350.9 CEP08348.1 - 4.2e-78 262.4 0.1 8.9e-78 261.3 0.1 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) GP67 PF17634.2 CEP08348.1 - 0.1 13.0 5.4 0.18 12.3 3.6 2.3 2 0 0 2 2 2 0 Gene product 67 HEAT PF02985.22 CEP08348.1 - 0.11 12.8 4.8 47 4.6 0.1 6.2 6 0 0 6 6 6 0 HEAT repeat Ribonuc_red_lgC PF02867.15 CEP08349.1 - 1.7e-189 630.7 0.0 2.2e-189 630.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEP08349.1 - 5e-24 84.1 0.1 1.4e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEP08349.1 - 2.2e-17 63.4 0.0 1.2e-16 61.0 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain Glyco_transf_15 PF01793.16 CEP08350.1 - 5.5e-109 364.4 13.7 7.7e-109 363.9 13.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SH3_9 PF14604.6 CEP08350.1 - 1.8e-43 146.2 0.4 6.9e-16 57.9 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CEP08350.1 - 2.2e-35 120.0 2.4 2.6e-11 42.9 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CEP08350.1 - 2.1e-33 113.8 0.0 5.5e-10 38.8 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.11 CEP08350.1 - 0.19 12.0 2.0 10 6.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial SH3 domain TPR_MalT PF17874.1 CEP08351.1 - 0.00098 18.6 0.2 0.0021 17.5 0.2 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 CEP08351.1 - 0.0016 18.2 0.1 0.56 10.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08351.1 - 0.0023 17.9 0.1 0.42 10.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP08351.1 - 0.16 12.4 1.1 2.1 8.9 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CEP08352.1 - 1.7e-16 59.8 0.1 3e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP08352.1 - 2.7e-07 30.2 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP08352.1 - 0.043 13.9 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif RRM_8 PF11835.8 CEP08352.1 - 0.18 12.0 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain Asp PF00026.23 CEP08353.1 - 1e-81 274.8 2.7 1.3e-81 274.5 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_L34e PF01199.18 CEP08353.1 - 3.5e-44 149.0 6.0 6.5e-44 148.2 6.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L34e TAXi_N PF14543.6 CEP08353.1 - 8e-06 26.2 0.6 0.0028 17.9 0.3 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP08353.1 - 1.8e-05 24.6 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP08353.1 - 0.15 12.7 0.1 14 6.4 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease MFS_1 PF07690.16 CEP08354.1 - 4.3e-16 58.8 22.7 8.1e-15 54.6 18.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CEP08354.1 - 1.7e-06 27.7 4.2 1.7e-06 27.7 4.2 2.0 2 0 0 2 2 2 1 Nodulin-like F-box-like PF12937.7 CEP08356.1 - 6.4e-06 26.0 0.3 1.4e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP08356.1 - 0.0018 18.1 0.1 0.006 16.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain Pectate_lyase_3 PF12708.7 CEP08356.1 - 0.08 12.8 0.8 0.37 10.6 0.8 2.2 1 1 0 1 1 1 0 Pectate lyase superfamily protein GcpE PF04551.14 CEP08356.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 GcpE protein BCAS2 PF05700.11 CEP08357.1 - 1.6e-63 214.1 12.3 1.8e-63 213.9 12.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF5398 PF17376.2 CEP08357.1 - 0.01 16.4 0.2 0.01 16.4 0.2 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5398) DUF3037 PF11236.8 CEP08357.1 - 0.033 14.6 0.8 0.076 13.4 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) MFS_1 PF07690.16 CEP08358.1 - 1.2e-14 54.0 31.0 2.8e-14 52.8 31.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CEP08358.1 - 6.2e-05 21.7 21.4 0.00094 17.8 9.1 2.9 1 1 1 3 3 3 3 MFS/sugar transport protein DUF3975 PF13126.6 CEP08358.1 - 3.3 8.2 12.2 0.26 11.8 1.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3975) Homeodomain PF00046.29 CEP08359.1 - 2.1e-06 27.5 0.9 4.7e-06 26.4 0.9 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP08359.1 - 0.027 14.3 0.1 0.066 13.1 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain Macoilin PF09726.9 CEP08359.1 - 2.7 6.4 15.0 3.1 6.2 15.0 1.1 1 0 0 1 1 1 0 Macoilin family Lipase_GDSL PF00657.22 CEP08360.1 - 8.8e-12 45.4 0.1 8.8e-12 45.4 0.1 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP08360.1 - 7.8e-06 26.4 0.0 1.4e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nmad2 PF18753.1 CEP08360.1 - 0.054 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 THB PF18362.1 CEP08360.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain Aa_trans PF01490.18 CEP08361.1 - 5.4e-89 298.7 33.2 5.4e-89 298.7 33.2 2.5 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 CEP08361.1 - 1.8e-10 40.3 22.5 1.8e-10 40.3 22.5 3.4 2 1 2 4 4 4 1 Major Facilitator Superfamily LSM PF01423.22 CEP08362.1 - 7.5e-21 73.6 0.1 8.3e-21 73.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEP08362.1 - 0.004 17.3 0.0 0.005 16.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CEP08362.1 - 0.0074 16.4 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain PI3K_rbd PF00794.18 CEP08362.1 - 0.045 13.9 0.2 0.1 12.8 0.2 1.6 1 1 0 1 1 1 0 PI3-kinase family, ras-binding domain ABC_membrane PF00664.23 CEP08363.1 - 9.8e-110 366.5 20.2 1.4e-58 198.7 7.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CEP08363.1 - 1.3e-68 229.8 0.1 7.6e-34 117.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Metallophos PF00149.28 CEP08363.1 - 4.4e-15 56.7 0.9 1.1e-14 55.5 0.9 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.19 CEP08363.1 - 1.9e-11 43.9 6.8 8.8e-06 25.3 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP08363.1 - 1.3e-08 35.2 0.6 0.0019 18.5 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP08363.1 - 7.2e-08 33.0 1.4 0.0047 17.3 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CEP08363.1 - 3.1e-06 26.3 0.5 0.019 13.8 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CEP08363.1 - 1.1e-05 25.4 1.0 0.22 11.4 0.1 3.1 3 0 0 3 3 3 2 RsgA GTPase Rad17 PF03215.15 CEP08363.1 - 1.6e-05 24.9 0.2 0.042 13.8 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_30 PF13604.6 CEP08363.1 - 2.9e-05 23.9 0.5 0.6 9.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain Metallophos_2 PF12850.7 CEP08363.1 - 5.5e-05 23.4 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_29 PF13555.6 CEP08363.1 - 9.9e-05 22.0 4.1 0.3 10.9 0.1 3.5 4 0 0 4 4 3 2 P-loop containing region of AAA domain G-alpha PF00503.20 CEP08363.1 - 0.00026 20.3 0.1 0.39 9.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 CEP08363.1 - 0.00032 20.3 0.1 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CEP08363.1 - 0.00042 20.5 0.0 1.7 8.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEP08363.1 - 0.00058 20.3 5.9 2.1 8.8 1.9 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEP08363.1 - 0.00064 19.1 0.2 0.28 10.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 CEP08363.1 - 0.0011 19.5 0.2 5.3 7.6 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 CEP08363.1 - 0.0044 17.0 0.6 12 5.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CEP08363.1 - 0.005 17.1 0.1 3.1 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CEP08363.1 - 0.0071 16.1 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CEP08363.1 - 0.0073 16.5 4.3 4.9 7.4 0.4 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 CEP08363.1 - 0.014 15.0 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 CEP08363.1 - 0.014 15.3 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 CEP08363.1 - 0.017 15.5 0.0 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CEP08363.1 - 0.024 14.0 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CEP08363.1 - 0.038 13.2 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 CEP08363.1 - 0.042 13.6 0.4 5.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 CEP08363.1 - 0.061 13.1 0.1 44 3.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CEP08363.1 - 0.078 12.5 0.7 13 5.2 0.3 3.0 3 0 0 3 3 3 0 AAA domain GMC_oxred_N PF00732.19 CEP08363.1 - 0.081 12.3 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase AAA_15 PF13175.6 CEP08363.1 - 0.095 12.4 1.0 2.6 7.6 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 CEP08363.1 - 2.1 8.8 8.5 17 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CEP08363.1 - 3.4 7.4 4.8 41 3.8 0.3 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein CotH PF08757.11 CEP08364.1 - 5.2e-38 131.4 7.4 8.3e-38 130.7 7.4 1.3 1 0 0 1 1 1 1 CotH kinase protein Sld5 PF05916.11 CEP08365.1 - 0.0014 19.0 1.9 0.0027 18.2 0.2 2.3 3 0 0 3 3 3 1 GINS complex protein HapK PF11639.8 CEP08365.1 - 0.0065 16.9 0.0 0.026 15.0 0.0 2.0 2 0 0 2 2 2 1 REDY-like protein HapK BRF1 PF07741.13 CEP08365.1 - 0.0093 16.3 3.7 0.0093 16.3 3.7 2.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain FliC_SP PF12613.8 CEP08365.1 - 0.17 12.4 2.5 0.44 11.1 2.5 1.7 1 0 0 1 1 1 0 Flagellin structural protein CotH PF08757.11 CEP08366.1 - 5.7e-24 85.2 1.0 7.1e-24 84.9 1.0 1.1 1 0 0 1 1 1 1 CotH kinase protein Lactamase_B_6 PF16661.5 CEP08367.1 - 9.7e-68 227.4 0.1 1.6e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CEP08367.1 - 4e-23 82.4 0.6 9.7e-18 64.9 0.0 2.6 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CEP08367.1 - 9.5e-21 74.2 0.0 2.3e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CEP08367.1 - 1.4e-10 41.0 0.0 2.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CEP08367.1 - 6.9e-06 26.2 0.1 1.2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP08367.1 - 1e-05 25.2 0.1 1.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CEP08367.1 - 0.011 15.0 0.1 0.038 13.2 0.1 1.8 1 1 0 1 1 1 0 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 CEP08367.1 - 0.027 14.4 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF4945 PF16303.5 CEP08368.1 - 0.054 13.4 1.2 0.26 11.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4945) DUF3209 PF11483.8 CEP08368.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) TRP PF06011.12 CEP08369.1 - 1.6e-46 158.9 31.7 2.4e-46 158.4 31.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 CEP08369.1 - 6.2e-05 23.4 0.1 0.00012 22.5 0.1 1.4 1 0 0 1 1 1 1 ML domain Ppx-GppA PF02541.16 CEP08370.1 - 5e-43 147.6 0.0 8.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SUI1 PF01253.22 CEP08372.1 - 1.4e-23 83.2 0.5 1.9e-23 82.8 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNF2_N PF00176.23 CEP08373.1 - 4.1e-65 219.8 0.4 2.8e-64 217.1 0.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP08373.1 - 4.7e-22 78.4 0.4 5e-19 68.7 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP08373.1 - 5.3e-10 39.6 0.0 2e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEP08373.1 - 2.9e-08 33.2 0.0 1.5e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CEP08373.1 - 3.9e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase TAA-Trp-ring PF15401.6 CEP08373.1 - 0.077 13.5 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin gag-asp_proteas PF13975.6 CEP08373.1 - 0.19 12.3 0.8 19 5.9 0.0 2.8 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease WD40 PF00400.32 CEP08374.1 - 8.8e-07 29.5 2.4 0.021 15.7 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_S17e PF00833.18 CEP08375.1 - 2.8e-62 208.1 0.2 3.2e-62 207.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Glyco_hydro_18 PF00704.28 CEP08376.1 - 1.9e-14 54.1 0.2 1.6e-13 51.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CEP08376.1 - 4.2e-08 33.1 0.5 4.2e-08 33.1 0.5 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) GATA PF00320.27 CEP08377.1 - 9.2e-16 57.2 5.6 2.2e-15 56.0 5.6 1.7 1 0 0 1 1 1 1 GATA zinc finger TauD PF02668.16 CEP08378.1 - 1.3e-40 139.9 0.2 1.7e-40 139.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RPA_C PF08784.11 CEP08379.1 - 9.5e-09 35.9 0.0 2.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CEP08379.1 - 2.3e-08 33.9 0.1 4e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HMGL-like PF00682.19 CEP08379.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 HMGL-like Peptidase_A22B PF04258.13 CEP08380.1 - 1.3e-85 287.4 11.1 1.8e-85 287.0 11.1 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CEP08380.1 - 0.0052 16.3 11.6 0.015 14.8 11.4 1.9 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease DUF2189 PF09955.9 CEP08380.1 - 0.11 12.8 5.6 0.05 13.9 2.2 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Protocadherin PF08374.11 CEP08380.1 - 0.15 12.0 2.4 0.35 10.8 2.4 1.6 1 0 0 1 1 1 0 Protocadherin PGA2 PF07543.12 CEP08380.1 - 3.2 7.7 10.9 0.25 11.3 5.5 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF2897 PF11446.8 CEP08380.1 - 3.9 7.4 5.7 19 5.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2897) DUF4536 PF15055.6 CEP08381.1 - 0.14 12.4 6.0 0.16 12.3 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Snf7 PF03357.21 CEP08382.1 - 0.17 11.5 3.2 0.32 10.6 3.2 1.5 1 0 0 1 1 1 0 Snf7 HLH PF00010.26 CEP08383.1 - 1.5e-18 66.4 0.6 5.4e-18 64.7 0.6 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1635 PF07795.11 CEP08383.1 - 0.0016 18.3 5.1 0.0016 18.3 5.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1635) CMS1 PF14617.6 CEP08384.1 - 9.6e-43 146.3 1.2 1.9e-42 145.4 1.2 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit GRAM PF02893.20 CEP08384.1 - 9.8e-24 83.4 0.3 2.3e-23 82.3 0.3 1.7 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 CEP08384.1 - 4.9e-19 69.3 1.1 4.9e-19 69.3 1.1 2.7 2 1 1 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain DEAD PF00270.29 CEP08384.1 - 8.2e-07 29.0 0.2 2.8e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TSGP1 PF07771.11 CEP08384.1 - 7.9 6.7 7.0 9.1 6.5 5.3 2.0 2 0 0 2 2 2 0 Tick salivary peptide group 1 DEAD PF00270.29 CEP08385.1 - 2.3e-48 164.3 0.0 3.9e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP08385.1 - 5.3e-33 113.7 0.3 3.8e-32 110.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP08385.1 - 1.4e-08 34.9 0.0 3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP08385.1 - 3e-06 26.7 0.1 5.8e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CEP08385.1 - 0.024 14.3 0.0 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Cyt-b5 PF00173.28 CEP08386.1 - 2.3e-21 75.7 0.2 2.3e-21 75.7 0.2 2.3 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CEP08386.1 - 3.7e-12 46.7 20.3 3.7e-12 46.7 20.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4260 PF14079.6 CEP08386.1 - 0.024 14.6 1.9 0.024 14.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) Anth_synt_I_N PF04715.13 CEP08386.1 - 0.1 12.8 0.3 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region TMEM189_B_dmain PF10520.9 CEP08386.1 - 0.31 11.1 8.0 0.068 13.3 1.6 2.3 1 1 0 2 2 2 0 B domain of TMEM189, localisation domain Gti1_Pac2 PF09729.9 CEP08387.1 - 1e-58 198.4 0.2 1e-58 198.4 0.2 3.1 2 2 0 2 2 2 1 Gti1/Pac2 family DDE_3 PF13358.6 CEP08388.1 - 4.7e-17 62.1 0.5 8.5e-17 61.3 0.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP08388.1 - 1.3e-16 60.6 0.7 2.9e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP08388.1 - 1.8e-07 31.7 1.4 4e-07 30.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP08388.1 - 3.8e-06 26.8 0.1 6.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP08388.1 - 0.00024 20.9 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CEP08388.1 - 0.0012 18.6 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP08388.1 - 0.0014 18.7 1.2 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 CEP08388.1 - 0.0014 18.1 0.1 0.085 12.4 0.0 3.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CEP08388.1 - 0.0037 17.0 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP08388.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP08388.1 - 0.025 14.7 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 CEP08388.1 - 0.13 12.1 0.1 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase HTH_19 PF12844.7 CEP08388.1 - 0.14 12.2 2.1 16 5.6 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain S-methyl_trans PF02574.16 CEP08389.1 - 4.4e-66 223.4 0.1 5e-66 223.3 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Sulfate_transp PF00916.20 CEP08390.1 - 4.6e-93 312.0 23.2 6e-93 311.6 23.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP08390.1 - 2.8e-10 39.9 0.0 5.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CEP08390.1 - 0.0069 16.7 0.0 0.044 14.1 0.0 2.2 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 CEP08390.1 - 0.6 10.5 19.3 0.023 15.1 3.9 3.0 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Na_H_antiport_2 PF13726.6 CEP08390.1 - 1.1 9.5 5.5 17 5.6 0.7 3.1 2 0 0 2 2 2 0 Na+-H+ antiporter family WAC_Acf1_DNA_bd PF10537.9 CEP08391.1 - 2.7e-32 111.3 0.4 7.9e-32 109.8 0.4 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CEP08391.1 - 1.6e-20 73.4 0.2 1.6e-20 73.4 0.2 3.4 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CEP08391.1 - 2.5e-16 59.7 0.2 4.3e-16 59.0 0.2 1.4 1 0 0 1 1 1 1 DDT domain LHH PF14411.6 CEP08391.1 - 0.034 14.3 1.5 0.082 13.1 1.5 1.7 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Fe-ADH PF00465.19 CEP08392.1 - 2.3e-107 359.0 0.1 2.8e-107 358.7 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CEP08392.1 - 9.3e-16 58.3 0.0 3.1e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 CEP08392.1 - 0.0031 17.2 0.1 0.0054 16.4 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein B12-binding PF02310.19 CEP08392.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain DAHP_snth_FXD PF18152.1 CEP08393.1 - 0.023 14.5 0.1 0.47 10.3 0.0 2.8 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain CHASE9 PF17153.4 CEP08393.1 - 0.047 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Pkinase PF00069.25 CEP08394.1 - 2.4e-69 233.7 0.0 3.2e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08394.1 - 3.6e-27 95.3 0.0 4.6e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP08394.1 - 1.2e-07 31.4 0.7 0.4 10.0 0.0 3.2 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.14 CEP08394.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP08394.1 - 0.032 13.0 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Sulfate_transp PF00916.20 CEP08395.1 - 5.8e-107 357.8 21.2 7.4e-107 357.4 21.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP08395.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP08395.1 - 4.6e-06 27.0 3.6 4.6e-06 27.0 3.6 3.5 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CEP08395.1 - 0.14 12.5 0.2 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 STAS domain ChAPs PF09295.10 CEP08396.1 - 1.1e-152 508.7 0.0 2.3e-151 504.3 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CEP08396.1 - 0.0021 18.5 0.4 0.41 11.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP08396.1 - 0.025 14.8 6.8 5.2 7.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08396.1 - 0.16 12.2 10.9 0.31 11.3 0.5 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MDM10 PF12519.8 CEP08396.1 - 4.5 6.0 7.5 6.7 5.4 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SAPS PF04499.15 CEP08396.1 - 4.7 5.9 12.2 8.2 5.1 12.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_hydro_17 PF00332.18 CEP08397.1 - 1.1e-15 58.1 1.2 3e-08 33.6 0.0 2.3 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 Complex1_51K PF01512.17 CEP08398.1 - 8.8e-49 165.3 0.0 1.3e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CEP08398.1 - 1.4e-24 86.0 0.3 2.9e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CEP08398.1 - 1.9e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 CEP08398.1 - 0.13 12.4 0.4 0.23 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) NIR_SIR PF01077.22 CEP08400.1 - 7.9e-51 171.7 0.0 3.9e-47 159.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 CEP08400.1 - 9.5e-31 106.9 0.1 2e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 CEP08400.1 - 2.3e-27 94.6 0.1 1.5e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 CEP08400.1 - 5.6e-18 65.5 0.2 1.4e-17 64.3 0.2 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 CEP08400.1 - 1.1e-08 35.3 0.0 4.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Flavodoxin_5 PF12724.7 CEP08400.1 - 0.0067 16.7 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 CEP08400.1 - 0.024 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain PilP PF04351.13 CEP08400.1 - 0.1 12.5 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 Pilus assembly protein, PilP zf-DNL PF05180.12 CEP08401.1 - 3.5e-32 110.1 0.7 3.5e-32 110.1 0.7 1.9 2 0 0 2 2 2 1 DNL zinc finger UPF0167 PF03691.14 CEP08401.1 - 0.7 9.7 6.4 1.2 9.0 3.2 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0167) NAT PF04768.13 CEP08402.1 - 1.4e-39 135.5 0.2 5.3e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 CEP08402.1 - 2.9e-31 108.9 0.1 1.2e-30 106.9 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 CEP08402.1 - 4e-30 104.7 0.0 1.1e-29 103.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 CEP08402.1 - 9.3e-10 38.9 0.0 2.2e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 CEP08402.1 - 0.016 15.3 0.0 0.058 13.5 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CEP08402.1 - 0.064 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_C PF16653.5 CEP08403.1 - 4.8e-92 308.8 0.0 1.7e-91 307.0 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CEP08403.1 - 8.2e-24 84.3 0.2 1.5e-23 83.5 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CEP08403.1 - 2.8e-07 30.7 0.0 5.5e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CEP08403.1 - 0.00068 19.6 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 CEP08403.1 - 0.0031 17.1 0.1 0.016 14.7 0.2 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP08403.1 - 0.045 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 CEP08403.1 - 0.052 13.0 0.1 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CEP08403.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 CEP08403.1 - 0.083 11.9 0.2 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CEP08403.1 - 0.11 12.0 0.1 0.36 10.3 0.0 1.9 3 0 0 3 3 3 0 short chain dehydrogenase Cpn60_TCP1 PF00118.24 CEP08404.1 - 5.9e-85 285.8 10.2 1.1e-84 284.9 10.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_aberr PF17017.5 CEP08405.1 - 2.7e-05 24.4 3.7 0.029 14.5 0.1 2.6 2 1 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CEP08405.1 - 0.001 19.4 13.5 0.056 13.9 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type CAF1C_H4-bd PF12265.8 CEP08405.1 - 0.079 13.2 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex zf-C2H2_4 PF13894.6 CEP08405.1 - 0.3 12.1 14.2 0.29 12.1 1.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP08405.1 - 0.5 10.9 0.2 0.5 10.9 0.2 3.7 3 1 0 3 3 3 0 Zinc-finger double domain UDPGT PF00201.18 CEP08406.1 - 2.7e-16 59.5 0.0 6.2e-15 55.0 0.0 2.6 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEP08406.1 - 9.1e-06 25.8 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain zf-C2H2_2 PF12756.7 CEP08407.1 - 5e-40 135.9 11.6 2.9e-31 107.8 0.1 3.6 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEP08407.1 - 9.3e-13 48.1 10.4 1.4e-09 37.9 6.0 4.4 5 1 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP08407.1 - 5.3e-08 33.0 10.9 5.3e-07 29.8 4.2 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 CEP08407.1 - 0.0077 16.3 0.8 0.0077 16.3 0.8 3.3 4 0 0 4 4 4 1 DBF zinc finger zf-LYAR PF08790.11 CEP08407.1 - 0.034 14.0 5.3 0.9 9.5 0.1 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 CEP08407.1 - 0.041 14.6 8.2 3.1 8.5 4.2 3.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-3CxxC_2 PF17180.4 CEP08407.1 - 0.11 13.2 5.8 0.24 12.2 2.5 2.6 2 0 0 2 2 2 0 Zinc-binding domain DUF1644 PF07800.12 CEP08407.1 - 0.11 12.5 6.5 0.37 10.9 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-C2H2_4 PF13894.6 CEP08407.1 - 0.18 12.7 0.5 0.18 12.7 0.5 5.3 6 0 0 6 6 5 0 C2H2-type zinc finger DUF4606 PF15379.6 CEP08407.1 - 0.3 11.4 5.2 0.72 10.1 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) Vps39_2 PF10367.9 CEP08407.1 - 7.7 7.0 7.5 1.3 9.5 0.6 3.0 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 DUF4820 PF16091.5 CEP08407.1 - 8 5.8 8.6 14 4.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MFS_1 PF07690.16 CEP08408.1 - 2.8e-36 125.2 73.4 2.1e-30 105.8 47.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP08408.1 - 1.1e-05 24.5 11.4 1.1e-05 24.5 11.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 CEP08408.1 - 1.5e-05 23.8 16.8 1.5e-05 23.8 16.8 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Oleosin PF01277.17 CEP08408.1 - 5.5 6.8 14.9 0.16 11.8 7.4 2.4 2 0 0 2 2 2 0 Oleosin MRI PF15325.6 CEP08409.1 - 0.21 12.7 2.8 0.61 11.2 2.8 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection Glyco_hydro_18 PF00704.28 CEP08410.1 - 1e-65 222.5 2.6 1.3e-65 222.1 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC1 PF03109.16 CEP08411.1 - 8.3e-29 100.2 0.1 2e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 ABC1 family HEPN_Swt1 PF18731.1 CEP08411.1 - 0.02 15.2 1.5 0.086 13.2 0.0 2.7 3 0 0 3 3 3 0 Swt1-like HEPN Ferritin_2 PF13668.6 CEP08411.1 - 0.088 13.0 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Ferritin-like domain CPSase_L_D2 PF02786.17 CEP08412.1 - 9e-66 221.4 0.0 2e-65 220.3 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEP08412.1 - 1e-42 145.1 0.0 2.1e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP08412.1 - 1.9e-36 124.4 0.0 8.4e-35 119.1 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain SGS PF05002.15 CEP08412.1 - 1.4e-31 108.5 0.6 3.8e-31 107.0 0.6 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CEP08412.1 - 8.3e-14 52.4 0.3 2.5e-13 50.9 0.3 1.9 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 CEP08412.1 - 2.6e-09 36.5 2.8 0.00049 20.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP08412.1 - 2.9e-07 30.9 0.2 0.0041 17.6 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Dala_Dala_lig_C PF07478.13 CEP08412.1 - 3.1e-07 30.1 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus TPR_12 PF13424.6 CEP08412.1 - 7.4e-06 26.2 3.0 0.0003 21.0 1.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP08412.1 - 7.5e-06 25.5 0.3 0.0011 18.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP08412.1 - 7.7e-06 26.3 0.6 0.48 11.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Biotin_lipoyl PF00364.22 CEP08412.1 - 1.5e-05 24.8 0.0 3.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CEP08412.1 - 4e-05 23.3 0.0 0.00011 21.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain TPR_16 PF13432.6 CEP08412.1 - 0.00032 21.3 0.6 0.03 15.0 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ATP-grasp_3 PF02655.14 CEP08412.1 - 0.00039 20.5 0.0 0.00073 19.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain TPR_7 PF13176.6 CEP08412.1 - 0.00054 19.8 1.1 1.1 9.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP08412.1 - 0.00099 18.8 0.0 0.027 14.1 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 CEP08412.1 - 0.0015 18.6 0.0 0.036 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat LAL_C2 PF18603.1 CEP08412.1 - 0.0027 17.8 0.2 0.0081 16.3 0.2 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 TPR_9 PF13371.6 CEP08412.1 - 0.0032 17.6 0.4 0.028 14.5 0.4 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP08412.1 - 0.0036 17.5 0.5 0.017 15.3 0.5 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CEP08412.1 - 0.0076 16.8 1.2 0.046 14.3 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 CEP08412.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2057 PF09829.9 CEP08412.1 - 0.16 12.1 4.1 0.061 13.5 1.0 1.9 2 0 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_10 PF13374.6 CEP08412.1 - 0.25 11.2 2.7 0.31 11.0 0.2 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat UMP1 PF05348.11 CEP08413.1 - 1.8e-38 131.4 0.4 2.1e-38 131.2 0.4 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MS_channel PF00924.18 CEP08414.1 - 7.5e-09 35.4 1.0 1.7e-08 34.3 1.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CEP08414.1 - 0.00061 19.2 0.1 0.0017 17.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CEP08414.1 - 0.00082 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CEP08414.1 - 0.0028 17.1 0.1 0.0084 15.6 0.1 1.7 1 0 0 1 1 1 1 EF hand Cytokin_check_N PF10407.9 CEP08414.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus EF-hand_7 PF13499.6 CEP08414.1 - 0.014 15.8 0.0 0.046 14.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair TraC_F_IV PF11130.8 CEP08419.1 - 0.0094 15.6 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 F pilus assembly Type-IV secretion system for plasmid transfer Cyclin_N PF00134.23 CEP08420.1 - 1.7e-11 44.0 0.1 2.6e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP08420.1 - 7.5e-08 32.9 0.1 1.3e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin zf-CCCH PF00642.24 CEP08421.1 - 1.4e-19 69.5 36.3 3.8e-05 23.5 0.3 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP08421.1 - 4.4e-16 58.3 59.3 1e-06 28.6 6.9 5.8 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 CEP08421.1 - 1.2e-13 51.7 43.7 6.3e-05 23.6 0.8 6.1 1 1 5 6 6 6 5 Torus domain zf-CCCH_4 PF18044.1 CEP08421.1 - 8.2e-10 38.2 45.4 3.2e-05 23.6 3.8 5.4 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CEP08421.1 - 2.7e-07 30.8 5.4 2.7e-07 30.8 5.4 3.5 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CEP08421.1 - 1e-06 28.9 48.1 0.0032 17.9 3.7 5.9 6 0 0 6 6 6 4 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 CEP08421.1 - 2.3e-06 27.4 3.6 2.3e-06 27.4 3.6 2.6 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 CEP08421.1 - 0.0096 16.3 4.4 0.018 15.4 4.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Per1 PF04080.13 CEP08422.1 - 2.8e-99 332.0 9.9 4.6e-99 331.3 9.9 1.4 1 0 0 1 1 1 1 Per1-like family NAD_binding_8 PF13450.6 CEP08422.1 - 1.9e-14 53.6 0.0 4.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP08422.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP08422.1 - 0.0021 18.1 0.0 0.61 10.1 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 CEP08422.1 - 0.016 14.0 0.0 0.043 12.6 0.0 1.7 2 0 0 2 2 2 0 MCRA family FAD_binding_2 PF00890.24 CEP08422.1 - 0.025 13.6 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CEP08422.1 - 0.053 12.8 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP08422.1 - 0.2 10.3 0.1 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Band_7 PF01145.25 CEP08423.1 - 4.5e-24 85.4 4.1 7.5e-24 84.7 4.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CEP08423.1 - 0.087 13.0 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Translin PF01997.16 CEP08424.1 - 2.4e-44 151.8 0.2 2.9e-44 151.5 0.2 1.1 1 0 0 1 1 1 1 Translin family BST2 PF16716.5 CEP08424.1 - 0.0038 17.8 0.2 0.012 16.1 0.2 1.8 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 CEP08424.1 - 0.0056 17.2 3.0 1.5 9.4 0.2 3.3 2 1 0 3 3 3 1 Syntaxin 6, N-terminal Intein_splicing PF14890.6 CEP08424.1 - 0.0065 16.4 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Intein splicing domain DUF1479 PF07350.12 CEP08424.1 - 0.022 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) PI_PP_I PF18363.1 CEP08424.1 - 0.048 13.8 0.8 2.5 8.3 0.1 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 CEP08424.1 - 0.06 13.4 0.6 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 CEP08424.1 - 0.091 13.2 1.8 0.48 10.9 0.2 2.5 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain GMP_synt_C PF00958.22 CEP08424.1 - 0.092 12.8 0.2 0.25 11.4 0.2 1.8 1 1 0 1 1 1 0 GMP synthase C terminal domain Nas2_N PF18265.1 CEP08424.1 - 0.24 11.3 4.9 0.27 11.2 0.2 2.8 3 0 0 3 3 3 0 Nas2 N_terminal domain MHYT PF03707.16 CEP08425.1 - 1.1e-21 76.7 18.7 6.1e-09 35.9 1.4 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Virul_fac_BrkB PF03631.15 CEP08425.1 - 2 8.0 18.0 3.8 7.1 18.0 1.4 1 0 0 1 1 1 0 Virulence factor BrkB DUF2070 PF09843.9 CEP08425.1 - 5.6 5.1 12.8 9.9 4.3 12.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Nucleopor_Nup85 PF07575.13 CEP08426.1 - 3.9e-35 121.5 12.9 1.2e-34 119.9 12.9 1.7 1 1 0 1 1 1 1 Nup85 Nucleoporin DUF4393 PF14337.6 CEP08426.1 - 0.045 13.5 0.3 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) TPR_1 PF00515.28 CEP08426.1 - 0.069 13.0 2.5 0.18 11.7 0.9 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08426.1 - 1.8 8.9 3.9 1.2 9.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 CEP08427.1 - 0.00014 22.4 4.5 0.12 13.3 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger Sigma70_ner PF04546.13 CEP08427.1 - 0.0075 16.2 1.4 0.0084 16.0 1.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region zf-C2H2_12 PF18658.1 CEP08427.1 - 0.014 14.9 1.7 4 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type DUF1188 PF06690.11 CEP08427.1 - 0.074 12.6 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) zf-C2H2_2 PF12756.7 CEP08427.1 - 0.09 13.1 1.8 0.42 11.0 1.8 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 CEP08428.1 - 1.3e-15 57.0 0.2 2e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP08428.1 - 0.02 15.0 0.0 0.056 13.6 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif DUF908 PF06012.12 CEP08428.1 - 8.6 5.7 12.1 15 4.8 12.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) eIF-1a PF01176.19 CEP08429.1 - 3.7e-21 74.7 0.1 5.1e-21 74.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-RVT PF13966.6 CEP08430.1 - 9.9e-08 32.6 0.8 2e-07 31.6 0.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HEAT_2 PF13646.6 CEP08433.1 - 6e-08 33.0 4.3 0.034 14.6 0.1 6.3 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 CEP08433.1 - 1.7e-05 24.6 18.7 7 7.2 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat Cnd1 PF12717.7 CEP08433.1 - 0.0046 17.0 3.5 6.1 6.9 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CEP08433.1 - 0.023 14.7 5.3 0.69 10.0 0.1 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribosomal_60s PF00428.19 CEP08433.1 - 0.063 13.9 0.9 0.43 11.2 0.9 2.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein HEAT_EZ PF13513.6 CEP08433.1 - 0.51 10.9 13.5 2.9 8.5 0.2 6.2 6 1 1 7 7 7 0 HEAT-like repeat DUF533 PF04391.12 CEP08434.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SIN1_PH PF16979.5 CEP08436.1 - 0.11 12.7 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology XFP PF03894.15 CEP08438.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase UCH PF00443.29 CEP08439.1 - 2.7e-44 151.6 1.0 6.1e-44 150.4 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP08439.1 - 2.5e-16 60.2 2.6 2.5e-16 60.2 2.6 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CEP08439.1 - 5.6e-05 23.6 0.0 0.00013 22.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CEP08439.1 - 0.0087 15.8 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger RVT_1 PF00078.27 CEP08440.1 - 7.9e-18 64.8 0.1 4.9e-17 62.2 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 CEP08441.1 - 1.5e-05 24.8 0.0 3.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP08441.1 - 0.00015 22.3 0.0 0.00036 21.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CEP08441.1 - 0.0011 18.5 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_psq PF05225.16 CEP08441.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_7 PF02796.15 CEP08441.1 - 0.014 15.5 0.0 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP08441.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DNA_pol_lambd_f PF10391.9 CEP08441.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda MerR_1 PF13411.6 CEP08441.1 - 0.13 12.3 0.3 2.6 8.2 0.1 2.5 1 1 1 2 2 2 0 MerR HTH family regulatory protein HTH_28 PF13518.6 CEP08441.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CEP08441.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc5 PF03221.16 CEP08442.1 - 1.5e-08 34.5 0.0 3.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 CEP08442.1 - 0.00032 20.3 0.1 0.0035 16.9 0.1 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 CEP08442.1 - 0.00088 19.8 0.0 0.0023 18.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain RVT_1 PF00078.27 CEP08443.1 - 1.3e-12 47.7 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP08446.1 - 2.4e-15 56.7 0.0 3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rap_GAP PF02145.15 CEP08447.1 - 1.2e-23 83.6 0.7 5.9e-23 81.4 0.0 2.3 3 0 0 3 3 3 1 Rap/ran-GAP Bac_surface_Ag PF01103.23 CEP08448.1 - 1.1e-46 159.9 0.3 1.5e-46 159.4 0.3 1.2 1 0 0 1 1 1 1 Surface antigen Ribosomal_L19 PF01245.20 CEP08448.1 - 0.03 14.2 0.2 0.13 12.2 0.1 2.0 1 1 1 2 2 2 0 Ribosomal protein L19 tRNA-synt_His PF13393.6 CEP08448.1 - 0.098 11.9 1.6 0.14 11.4 1.6 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Nop14 PF04147.12 CEP08449.1 - 9.5e-284 943.9 42.6 1.1e-283 943.7 42.6 1.0 1 0 0 1 1 1 1 Nop14-like family bZIP_1 PF00170.21 CEP08450.1 - 2.4e-09 37.1 11.9 2.4e-09 37.1 11.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP08450.1 - 7e-06 26.0 11.2 7e-06 26.0 11.2 1.7 2 0 0 2 2 2 1 Basic region leucine zipper Speriolin_N PF15058.6 CEP08450.1 - 0.0033 17.5 0.3 0.0033 17.5 0.3 2.1 2 0 0 2 2 2 1 Speriolin N terminus Kinesin_assoc PF16183.5 CEP08450.1 - 0.06 13.5 0.2 0.18 11.9 0.1 1.9 2 0 0 2 2 2 0 Kinesin-associated OsmC PF02566.19 CEP08450.1 - 0.096 13.2 0.1 0.2 12.2 0.1 1.6 1 0 0 1 1 1 0 OsmC-like protein CTNNB1_binding PF08347.11 CEP08450.1 - 0.24 11.6 3.4 0.22 11.7 0.5 2.1 1 1 1 2 2 2 0 N-terminal CTNNB1 binding bZIP_Maf PF03131.17 CEP08450.1 - 0.47 11.0 9.8 0.27 11.8 6.5 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Metallophos PF00149.28 CEP08451.1 - 7.8e-12 46.1 2.7 1.7e-11 45.1 2.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 CEP08451.1 - 0.05 13.8 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain GDA1_CD39 PF01150.17 CEP08452.1 - 3.7e-99 332.3 0.0 4.8e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pkinase PF00069.25 CEP08453.1 - 9.1e-73 244.9 0.0 1.7e-72 244.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08453.1 - 5.3e-35 121.0 0.0 1.4e-34 119.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP08453.1 - 0.00043 19.7 1.2 0.34 10.2 0.0 3.1 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CEP08453.1 - 0.0051 15.6 0.2 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CEP08453.1 - 0.068 12.8 0.8 0.33 10.5 0.8 2.0 1 1 0 1 1 1 0 RIO1 family PhzC-PhzF PF02567.16 CEP08453.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein APH PF01636.23 CEP08453.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family 4HBT_2 PF13279.6 CEP08454.1 - 1.3e-12 48.3 0.2 3.3e-12 47.0 0.2 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 CEP08454.1 - 0.00065 19.1 0.4 0.00099 18.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase HAGH_C PF16123.5 CEP08455.1 - 6.3e-25 87.5 0.0 9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEP08455.1 - 5.9e-09 36.2 4.8 2.6e-07 30.8 4.4 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP08455.1 - 0.00094 18.7 0.1 0.01 15.4 0.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AhpC-TSA PF00578.21 CEP08456.1 - 1.5e-36 125.0 0.0 4.1e-36 123.6 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CEP08456.1 - 1.2e-14 54.2 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEP08456.1 - 7.9e-13 48.0 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin KTI12 PF08433.10 CEP08457.1 - 6.6e-82 275.0 0.0 5e-81 272.1 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CEP08457.1 - 1.2e-05 25.5 0.0 0.00016 21.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 CEP08458.1 - 2.7e-07 30.2 0.0 3.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain adh_short_C2 PF13561.6 CEP08459.1 - 8e-53 179.4 3.5 1.8e-43 148.8 1.6 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP08459.1 - 5.9e-47 159.6 1.9 7.1e-47 159.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP08459.1 - 2.8e-14 53.4 0.4 4.4e-14 52.8 0.4 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 CEP08459.1 - 2e-05 24.7 0.2 3.3e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 CEP08459.1 - 0.01 15.7 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IGPD PF00475.18 CEP08460.1 - 2.9e-62 209.2 0.6 3.9e-62 208.8 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TRAM_LAG1_CLN8 PF03798.16 CEP08461.1 - 1.4e-42 145.7 26.2 1.4e-42 145.7 26.2 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CEP08461.1 - 5.5e-16 58.0 1.3 5.5e-16 58.0 1.3 2.5 2 0 0 2 2 2 1 TRAM1-like protein TPP_enzyme_N PF02776.18 CEP08462.1 - 1.1e-27 96.7 0.1 2.5e-27 95.6 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEP08462.1 - 8.3e-18 64.4 0.0 1.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CEP08462.1 - 1.7e-17 63.6 0.0 3.7e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CEP08462.1 - 0.0077 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RVT_1 PF00078.27 CEP08463.1 - 3.2e-06 26.8 0.0 6.4e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP08464.1 - 0.0099 15.9 2.4 0.0099 15.9 2.4 3.1 4 0 0 4 4 4 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP08464.1 - 0.023 14.4 2.4 0.023 14.4 2.4 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger CEP44 PF15007.6 CEP08464.1 - 0.039 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 zf-CCHC_4 PF14392.6 CEP08464.1 - 0.27 11.0 7.6 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle EzrA PF06160.12 CEP08467.1 - 0.019 13.2 0.8 0.021 13.0 0.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Apolipoprotein PF01442.18 CEP08467.1 - 0.026 14.4 0.7 0.034 14.0 0.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CEP08467.1 - 0.039 14.0 1.3 0.087 12.9 1.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LTXXQ PF07813.12 CEP08467.1 - 0.059 14.1 0.1 0.085 13.6 0.1 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein AATF-Che1 PF13339.6 CEP08468.1 - 0.03 15.0 0.9 0.043 14.5 0.8 1.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor MPC PF03650.13 CEP08470.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers MFS_1 PF07690.16 CEP08471.1 - 8.2e-35 120.4 19.7 8.2e-35 120.4 19.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CEP08471.1 - 1.1e-05 24.0 4.0 1.5e-05 23.5 0.7 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 CEP08471.1 - 0.00014 21.7 0.3 0.035 13.9 0.0 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tmemb_161AB PF10268.9 CEP08471.1 - 0.022 13.4 0.1 0.052 12.2 0.1 1.6 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB ARA70 PF12489.8 CEP08471.1 - 0.046 13.9 0.6 0.085 13.1 0.6 1.3 1 0 0 1 1 1 0 Nuclear coactivator DUF4131 PF13567.6 CEP08471.1 - 0.35 10.5 3.7 6.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) YCII PF03795.14 CEP08472.1 - 9.1e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 YCII-related domain RVT_1 PF00078.27 CEP08473.1 - 0.0058 16.2 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_SOX PF18371.1 CEP08473.1 - 0.031 14.6 0.8 2.5 8.5 0.3 2.5 1 1 2 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase COX16 PF14138.6 CEP08473.1 - 0.079 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4220 PF13968.6 CEP08473.1 - 0.094 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) BNIP3 PF06553.12 CEP08474.1 - 9.2e-05 22.2 2.6 9.2e-05 22.2 2.6 2.3 2 0 0 2 2 2 1 BNIP3 Exo_endo_phos_2 PF14529.6 CEP08474.1 - 0.0012 18.6 0.0 0.034 14.0 0.0 4.3 4 1 1 5 5 5 2 Endonuclease-reverse transcriptase Swi5 PF07061.11 CEP08474.1 - 0.75 9.9 0.0 0.75 9.9 0.0 4.2 4 1 0 4 4 4 0 Swi5 Zip PF02535.22 CEP08474.1 - 0.93 8.6 2.7 1.7 7.8 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RPA43_OB PF17875.1 CEP08474.1 - 3.7 8.2 10.6 6.7 7.4 2.2 3.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Neur_chan_memb PF02932.16 CEP08474.1 - 6.5 6.7 8.8 15 5.5 8.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3533 PF12051.8 CEP08474.1 - 8.8 5.1 8.2 18 4.1 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF1604 PF07713.13 CEP08476.1 - 4e-38 129.1 2.1 4e-38 129.1 2.1 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.23 CEP08476.1 - 8.8e-09 35.1 0.0 2.8e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP08476.1 - 0.00039 20.4 0.6 0.0035 17.4 0.1 3.0 2 1 0 2 2 2 1 G-patch domain gag-asp_proteas PF13975.6 CEP08477.1 - 1.7e-06 28.5 0.1 3.5e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CEP08477.1 - 7.2e-05 23.0 0.5 0.00023 21.4 0.5 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 CEP08477.1 - 9.4e-05 22.2 3.1 0.00016 21.5 2.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP08477.1 - 0.00035 21.2 0.1 0.00083 19.9 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CEP08477.1 - 0.0061 16.3 0.1 0.014 15.2 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease DUF3695 PF12494.8 CEP08477.1 - 0.057 13.3 1.8 0.12 12.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) IBN_N PF03810.19 CEP08479.1 - 0.042 13.8 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain zf-RVT PF13966.6 CEP08480.1 - 2.1e-07 31.6 0.4 5.1e-07 30.3 0.4 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Lpp-LpqN PF10738.9 CEP08481.1 - 0.012 15.1 1.0 0.021 14.3 0.1 1.8 2 0 0 2 2 2 0 Probable lipoprotein LpqN Fungal_trans PF04082.18 CEP08482.1 - 7.6e-23 80.9 1.9 7.6e-23 80.9 1.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP08482.1 - 1.8e-08 34.3 13.3 3.4e-08 33.5 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suf PF05843.14 CEP08482.1 - 0.062 13.3 5.4 0.14 12.1 5.4 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Drf_GBD PF06371.13 CEP08482.1 - 0.34 10.5 4.8 0.81 9.2 4.8 1.6 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.32 CEP08483.1 - 1.8e-24 85.5 8.3 3.5e-05 24.5 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08483.1 - 6.7e-09 35.9 3.6 0.08 13.3 0.2 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP08483.1 - 0.00066 18.4 0.0 3.2 6.3 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 CEP08483.1 - 0.0028 16.8 0.2 0.0047 16.0 0.2 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 CEP08483.1 - 0.0082 15.5 1.0 0.037 13.3 0.4 2.1 2 1 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 CEP08483.1 - 0.025 14.6 0.4 0.65 10.1 0.1 3.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 CEP08483.1 - 0.037 12.3 0.3 0.2 10.0 0.1 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz ABC_membrane PF00664.23 CEP08484.1 - 3.1e-51 174.6 32.9 1.6e-33 116.5 12.1 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP08484.1 - 1.6e-43 148.5 0.6 9.5e-29 100.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CEP08484.1 - 1.6e-07 31.0 2.7 0.0031 17.0 2.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CEP08484.1 - 1.2e-05 24.6 0.0 0.036 13.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 CEP08484.1 - 0.0013 18.4 0.1 0.54 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEP08484.1 - 0.0015 18.2 1.5 0.55 10.0 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 CEP08484.1 - 0.0034 17.5 0.6 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 CEP08484.1 - 0.0057 16.9 0.2 1.4 9.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 CEP08484.1 - 0.0065 16.5 0.0 1 9.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 CEP08484.1 - 0.008 15.1 0.2 2 7.2 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 CEP08484.1 - 0.019 14.3 2.5 1.9 7.8 0.0 3.3 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 CEP08484.1 - 0.021 14.6 1.4 0.039 13.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CEP08484.1 - 0.024 13.9 0.4 1.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CEP08484.1 - 0.044 14.3 5.3 0.93 10.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 CEP08484.1 - 0.071 12.8 0.0 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 CEP08484.1 - 0.13 12.6 5.0 4.4 7.7 0.1 3.2 3 1 0 4 4 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEP08484.1 - 0.31 10.4 1.4 20 4.5 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 CEP08484.1 - 0.43 9.7 2.5 1 8.5 0.1 2.8 3 1 0 3 3 3 0 NB-ARC domain Pes-10 PF07149.11 CEP08484.1 - 0.47 9.5 4.3 0.093 11.8 0.2 1.7 2 0 0 2 2 2 0 Pes-10 NOA36 PF06524.12 CEP08484.1 - 5.3 6.3 9.8 10 5.3 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L23eN PF03939.13 CEP08485.1 - 1.7e-23 82.6 8.4 3.3e-23 81.7 8.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CEP08485.1 - 6e-16 58.6 5.2 2.8e-15 56.4 2.6 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L7Ae PF01248.26 CEP08486.1 - 2.1e-27 94.7 2.2 2.6e-27 94.4 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4911 PF16256.5 CEP08486.1 - 0.11 12.5 0.1 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) Ribosomal_S7e PF01251.18 CEP08487.1 - 3.7e-82 274.5 0.3 4.2e-82 274.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF1382 PF07131.11 CEP08487.1 - 0.086 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Sel1 PF08238.12 CEP08488.1 - 1.7e-110 358.9 56.7 3.5e-11 43.4 0.0 15.8 16 0 0 16 16 16 13 Sel1 repeat TPR_6 PF13174.6 CEP08488.1 - 0.0013 19.2 11.1 1.7 9.5 0.1 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat Ribosomal_L28e PF01778.17 CEP08488.1 - 0.039 14.7 0.3 16 6.3 0.0 3.9 3 1 1 4 4 4 0 Ribosomal L28e protein family Fib_succ_major PF09603.10 CEP08488.1 - 0.061 14.0 9.4 7.4 7.2 0.7 4.2 1 1 2 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) TPR_17 PF13431.6 CEP08488.1 - 7.2 7.2 15.6 25 5.6 0.6 7.2 7 1 1 8 8 8 0 Tetratricopeptide repeat ERG4_ERG24 PF01222.17 CEP08489.1 - 1.5e-142 475.4 15.4 1.7e-142 475.2 15.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_L11_N PF03946.14 CEP08490.1 - 1.8e-23 82.1 0.1 3.6e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEP08490.1 - 1.9e-16 60.3 0.1 4e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain EF-hand_1 PF00036.32 CEP08490.1 - 5.6e-07 28.7 0.4 5.6e-07 28.7 0.4 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CEP08490.1 - 6.7e-07 28.7 2.9 3.8e-06 26.4 0.2 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CEP08490.1 - 8.7e-07 29.3 1.8 3e-06 27.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CEP08490.1 - 9.9e-06 24.8 0.0 2.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CEP08490.1 - 0.0087 15.9 1.3 0.019 14.8 0.5 2.0 2 0 0 2 2 2 1 EF-hand domain pair Macoilin PF09726.9 CEP08490.1 - 0.24 9.9 7.5 0.28 9.7 7.5 1.1 1 0 0 1 1 1 0 Macoilin family EF-hand_4 PF12763.7 CEP08490.1 - 0.24 11.3 1.2 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand GREB1 PF15782.5 CEP08490.1 - 0.35 7.9 6.8 0.41 7.7 6.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SWI-SNF_Ssr4 PF08549.10 CEP08490.1 - 1.7 7.2 6.8 2.4 6.7 6.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ADH_zinc_N PF00107.26 CEP08491.1 - 1.8e-24 86.1 0.1 3.4e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP08491.1 - 2.5e-18 67.4 0.1 8.1e-18 65.8 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP08491.1 - 4.4e-08 33.0 0.0 1.4e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CEP08491.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF4434 PF14488.6 CEP08491.1 - 0.091 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Peptidase_M24 PF00557.24 CEP08492.1 - 1.3e-59 201.4 0.1 1.8e-59 200.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEP08492.1 - 2.8e-24 85.2 0.0 6.1e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 CEP08492.1 - 0.034 14.2 0.1 0.075 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) TPR_1 PF00515.28 CEP08494.1 - 1.7e-50 166.9 39.2 6.2e-08 32.1 0.1 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08494.1 - 7.4e-45 147.5 34.0 5.8e-06 26.0 0.1 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEP08494.1 - 1.3e-33 112.3 29.7 3e-05 23.9 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 CEP08494.1 - 3.7e-27 92.7 26.6 0.00077 19.7 0.1 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEP08494.1 - 8.9e-26 90.2 15.9 6.6e-05 23.4 0.1 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEP08494.1 - 5.7e-25 87.7 13.2 1.3e-06 29.0 0.1 7.1 5 1 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEP08494.1 - 1.1e-23 81.9 13.1 0.004 17.9 0.0 9.2 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 CEP08494.1 - 7.6e-23 80.6 26.0 2.6e-05 24.4 2.4 7.1 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CEP08494.1 - 8.7e-20 70.1 43.1 9.2e-06 25.2 1.4 9.8 5 2 5 10 10 10 5 TPR repeat TPR_7 PF13176.6 CEP08494.1 - 2.5e-18 64.7 21.6 0.038 14.0 0.5 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.6 CEP08494.1 - 1.4e-17 63.1 28.3 0.001 19.6 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEP08494.1 - 1.3e-16 60.5 13.6 0.00035 20.7 0.4 6.7 2 2 6 8 8 8 8 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP08494.1 - 1.8e-10 40.9 19.1 5.2e-06 26.6 5.2 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEP08494.1 - 4.9e-05 22.7 26.4 0.14 11.4 0.2 5.5 2 1 5 7 7 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 CEP08494.1 - 1.9 8.4 24.3 20 5.2 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEP08494.1 - 5.3 7.1 20.0 7.4 6.7 0.7 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CEP08494.1 - 6.9 6.8 29.5 5.8 7.1 0.4 7.2 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain EI24 PF07264.11 CEP08495.1 - 8.9e-24 84.7 23.9 8.9e-24 84.7 23.9 2.6 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Tetraspanin PF00335.20 CEP08495.1 - 5.1e-16 59.1 3.2 5.1e-16 59.1 3.2 3.2 3 0 0 3 3 3 1 Tetraspanin family PAP2 PF01569.21 CEP08496.1 - 5e-05 23.1 7.2 6e-05 22.8 1.3 2.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CEP08496.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 Divergent PAP2 family DUF1430 PF07242.11 CEP08496.1 - 0.12 12.6 3.0 5.4 7.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) PUF PF00806.19 CEP08497.1 - 7.9e-62 201.6 16.8 2.7e-10 39.3 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 CEP08497.1 - 0.00016 21.5 0.8 0.00041 20.2 0.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CPL PF08144.11 CEP08497.1 - 0.0011 19.4 1.5 1.6 9.1 0.3 4.4 1 1 1 3 3 3 1 CPL (NUC119) domain PAT1 PF09770.9 CEP08497.1 - 0.014 13.8 0.3 0.014 13.8 0.3 2.6 2 1 1 3 3 3 0 Topoisomerase II-associated protein PAT1 ArgoMid PF16487.5 CEP08497.1 - 0.034 14.4 0.2 0.44 10.8 0.2 2.7 2 0 0 2 2 2 0 Mid domain of argonaute zf_CCCH_4 PF18345.1 CEP08497.1 - 0.036 14.1 2.0 0.1 12.7 2.0 1.8 1 0 0 1 1 1 0 Zinc finger domain Mito_fiss_reg PF05308.11 CEP08497.1 - 5.8 6.9 8.3 1.1 9.3 1.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.16 CEP08498.1 - 1.4e-31 109.7 61.1 9.1e-25 87.3 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEP08498.1 - 0.0023 16.5 15.4 0.0023 16.5 15.4 2.7 1 1 0 2 2 2 2 MFS/sugar transport protein GMC_oxred_N PF00732.19 CEP08499.1 - 3.6e-66 223.5 0.0 4.8e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEP08499.1 - 8.1e-32 110.7 0.0 1.3e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CEP08499.1 - 1.8e-05 24.9 0.3 0.00014 22.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP08499.1 - 6.8e-05 22.6 0.1 0.0027 17.4 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP08499.1 - 0.00055 19.1 0.1 0.0011 18.1 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 CEP08499.1 - 0.00063 18.9 0.0 0.00099 18.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CEP08499.1 - 0.0007 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEP08499.1 - 0.0091 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CEP08499.1 - 0.022 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 CEP08499.1 - 0.034 14.7 0.2 0.14 12.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP08499.1 - 0.047 12.4 0.0 0.082 11.6 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 CEP08499.1 - 0.059 12.6 0.0 8.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 CEP08499.1 - 0.062 12.6 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEP08499.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 CEP08499.1 - 0.073 13.3 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 CEP08499.1 - 0.17 11.2 0.3 0.29 10.4 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase YjeJ PF15922.5 CEP08499.1 - 0.18 11.0 0.2 8.6 5.5 0.1 2.3 2 0 0 2 2 2 0 YjeJ-like IDO PF01231.18 CEP08500.1 - 8.4e-44 150.0 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DPBB_1 PF03330.18 CEP08501.1 - 3.7e-08 33.5 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase PAS PF00989.25 CEP08502.1 - 0.00017 21.6 0.8 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold TFIIA PF03153.13 CEP08502.1 - 0.0039 17.2 17.2 0.0056 16.7 17.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CEP08502.1 - 0.045 12.5 3.8 0.071 11.9 3.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Suf PF05843.14 CEP08502.1 - 0.053 13.5 8.7 0.079 12.9 8.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MPM1 PF17234.2 CEP08502.1 - 0.14 12.4 5.5 0.4 10.9 5.5 1.7 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 PAT1 PF09770.9 CEP08502.1 - 0.43 8.8 14.5 0.55 8.4 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.9 CEP08502.1 - 5.5 6.1 21.6 9.7 5.3 21.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SprA-related PF12118.8 CEP08502.1 - 6 5.9 19.2 0.052 12.7 9.8 2.0 2 0 0 2 2 2 0 SprA-related family Roughex PF06020.11 CEP08502.1 - 9.9 5.1 9.9 18 4.3 9.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DDE_3 PF13358.6 CEP08503.1 - 2.3e-06 27.4 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Mito_carr PF00153.27 CEP08504.1 - 6e-56 186.4 4.5 5.8e-18 64.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NTP_transferase PF00483.23 CEP08506.1 - 2.3e-18 66.7 0.0 3.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CEP08506.1 - 2.4e-08 34.5 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_hydro_8 PF01270.17 CEP08508.1 - 3.5e-22 78.7 1.3 5.5e-22 78.1 1.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 MPLKIP PF15502.6 CEP08509.1 - 9.2e-08 32.2 1.0 9.3e-08 32.2 0.1 1.5 2 0 0 2 2 2 1 M-phase-specific PLK1-interacting protein FoP_duplication PF13865.6 CEP08509.1 - 0.0013 19.2 2.3 0.0017 18.9 2.3 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 LSM PF01423.22 CEP08510.1 - 1.4e-10 40.7 0.2 1.7e-10 40.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEP08510.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Septin PF00735.18 CEP08511.1 - 7.2e-112 373.2 0.3 8.8e-112 373.0 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP08511.1 - 3.1e-09 36.9 0.2 3.1e-08 33.7 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP08511.1 - 5e-07 29.8 0.5 2.7e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CEP08511.1 - 3.7e-06 26.4 0.0 7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CEP08511.1 - 3.9e-05 23.3 0.1 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEP08511.1 - 0.00022 21.7 0.2 0.0012 19.2 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 CEP08511.1 - 0.00043 20.4 0.9 0.74 9.8 0.3 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 CEP08511.1 - 0.001 18.3 0.8 0.0017 17.6 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain Gtr1_RagA PF04670.12 CEP08511.1 - 0.0017 17.7 0.2 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 CEP08511.1 - 0.0032 17.5 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP08511.1 - 0.0038 16.8 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CEP08511.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEP08511.1 - 0.0055 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CEP08511.1 - 0.0064 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 CEP08511.1 - 0.0069 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Roc PF08477.13 CEP08511.1 - 0.0075 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CEP08511.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CEP08511.1 - 0.027 13.6 0.6 0.33 10.0 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit T2SSE PF00437.20 CEP08511.1 - 0.058 12.4 0.1 0.18 10.8 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 CEP08511.1 - 0.062 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras family RuvB_N PF05496.12 CEP08511.1 - 0.074 12.8 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CEP08511.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 CEP08511.1 - 0.092 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 CEP08511.1 - 0.094 12.9 0.3 0.35 11.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP08511.1 - 0.18 11.5 0.1 0.59 9.8 0.0 1.9 3 0 0 3 3 2 0 AAA domain HisG PF01634.18 CEP08512.1 - 2.4e-54 183.6 0.3 3.3e-54 183.2 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CEP08512.1 - 1.6e-27 95.4 0.6 4.1e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 CEP08512.1 - 7.9e-06 26.0 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like UreF PF01730.16 CEP08513.1 - 1.5e-22 80.6 0.1 2.3e-22 80.0 0.0 1.3 2 0 0 2 2 2 1 UreF Aldo_ket_red PF00248.21 CEP08514.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Herpes_UL7 PF01677.16 CEP08514.1 - 0.048 13.4 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus UL7 like Redoxin PF08534.10 CEP08514.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Redoxin DUF3194 PF11419.8 CEP08514.1 - 0.078 13.4 0.0 0.28 11.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3194) Mg_trans_NIPA PF05653.14 CEP08515.1 - 5.7e-80 268.6 23.4 7.1e-80 268.3 23.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEP08515.1 - 1.6e-06 28.3 7.6 1.6e-06 28.3 7.6 2.9 2 1 0 2 2 2 1 EamA-like transporter family Gaa1 PF04114.14 CEP08515.1 - 2.5 7.0 10.3 3.1 6.7 10.3 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF4763 PF15960.5 CEP08517.1 - 0.00016 21.1 35.1 0.024 13.9 22.2 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4763) Tropomyosin_1 PF12718.7 CEP08517.1 - 0.011 15.9 8.6 0.011 15.9 8.6 3.5 1 1 2 3 3 3 0 Tropomyosin like Laminin_II PF06009.12 CEP08517.1 - 1.2 9.1 34.9 0.7 9.9 3.9 3.7 1 1 1 3 3 3 0 Laminin Domain II DUF3584 PF12128.8 CEP08517.1 - 4 4.8 46.8 3.3 5.1 33.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 CEP08517.1 - 6.6 7.1 22.0 8.1 6.8 0.3 4.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 CEP08517.1 - 9.8 6.2 48.6 15 5.6 4.8 4.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HLH PF00010.26 CEP08519.1 - 7e-17 61.1 0.0 2.9e-16 59.1 0.0 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Fib_alpha PF08702.10 CEP08519.1 - 0.039 14.1 0.3 0.052 13.7 0.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Gcd10p PF04189.13 CEP08519.1 - 0.1 11.7 0.5 0.12 11.4 0.5 1.1 1 0 0 1 1 1 0 Gcd10p family YopX PF09643.10 CEP08519.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 YopX protein TFR_dimer PF04253.15 CEP08519.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.4 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain PPR_2 PF13041.6 CEP08520.1 - 2.3e-59 197.4 15.5 7.6e-09 35.6 0.5 14.7 9 4 7 16 16 16 10 PPR repeat family PPR_3 PF13812.6 CEP08520.1 - 4.5e-34 116.3 11.2 5.4e-06 26.4 0.0 11.3 10 3 3 13 13 13 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP08520.1 - 2e-27 94.6 10.9 0.0004 20.0 0.0 12.5 13 1 0 13 13 13 5 PPR repeat PPR_long PF17177.4 CEP08520.1 - 2.1e-24 86.1 2.3 7.9e-09 35.2 0.0 5.6 3 2 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEP08520.1 - 4.1e-21 73.7 27.3 0.1 12.9 0.0 15.8 19 0 0 19 19 19 6 PPR repeat RPM2 PF08579.11 CEP08520.1 - 1e-06 29.1 5.3 0.41 11.1 0.1 7.5 7 1 1 8 8 8 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 CEP08520.1 - 2.7e-05 24.6 0.5 6.1 8.0 0.1 7.7 9 1 1 10 10 10 1 Tetratricopeptide repeat Fumarate_red_C PF02300.17 CEP08520.1 - 0.18 11.9 1.5 0.35 11.0 0.5 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit C DUF3439 PF11921.8 CEP08520.1 - 5 7.1 9.0 12 5.9 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cytochrom_C_2 PF01322.20 CEP08522.1 - 0.0079 17.1 0.1 3.6 8.5 0.0 2.8 3 0 0 3 3 3 2 Cytochrome C' HNH PF01844.23 CEP08522.1 - 0.03 14.5 0.1 0.03 14.5 0.1 1.8 2 0 0 2 2 2 0 HNH endonuclease zf-CCHC_4 PF14392.6 CEP08522.1 - 1.5 8.7 5.9 9.2 6.1 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle CH PF00307.31 CEP08525.1 - 7e-85 280.4 0.4 7.6e-20 71.1 0.0 4.4 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CEP08525.1 - 9.4e-10 38.8 1.0 3.1e-09 37.2 0.4 2.3 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 CEP08525.1 - 1.6e-09 37.4 0.1 0.013 15.3 0.0 4.4 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.32 CEP08525.1 - 4.6e-07 28.9 1.3 0.059 12.9 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CEP08525.1 - 2.4e-06 27.0 0.8 0.0068 16.3 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CEP08525.1 - 7.9e-05 22.0 1.9 0.25 10.9 0.0 3.0 2 0 0 2 2 2 2 EF hand RNB PF00773.19 CEP08525.1 - 0.00063 19.2 0.4 0.0011 18.4 0.4 1.2 1 0 0 1 1 1 1 RNB domain EF-hand_8 PF13833.6 CEP08525.1 - 0.00094 19.0 0.4 2.3 8.1 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain pair CH_2 PF06294.11 CEP08525.1 - 0.037 14.2 0.2 30 4.8 0.0 3.6 4 0 0 4 4 4 0 CH-like domain in sperm protein LSM PF01423.22 CEP08525.1 - 0.094 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 LSM domain Imm3 PF14425.6 CEP08525.1 - 3.2 7.8 7.0 6.4 6.9 0.0 4.2 4 1 1 5 5 5 0 Immunity protein Imm3 Actin PF00022.19 CEP08526.1 - 6.6e-27 94.1 0.1 8.2e-26 90.5 0.1 2.2 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 CEP08526.1 - 5.7e-16 58.7 6.9 2.9e-08 33.3 0.1 2.8 3 0 0 3 3 3 2 Putative actin-like family MreB_Mbl PF06723.13 CEP08526.1 - 1.3e-05 24.2 0.0 0.00061 18.7 0.0 2.5 2 0 0 2 2 2 1 MreB/Mbl protein CENP-F_leu_zip PF10473.9 CEP08526.1 - 7.4e-05 22.8 2.0 0.00017 21.7 2.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsA PF14450.6 CEP08526.1 - 0.0007 20.0 0.2 0.0026 18.2 0.2 2.1 1 1 0 1 1 1 1 Cell division protein FtsA FPP PF05911.11 CEP08526.1 - 0.0071 14.6 7.8 0.012 13.8 7.8 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FlxA PF14282.6 CEP08526.1 - 0.021 14.8 11.9 0.05 13.6 11.9 1.6 1 0 0 1 1 1 0 FlxA-like protein Tropomyosin_1 PF12718.7 CEP08526.1 - 0.021 15.0 9.2 0.046 13.9 9.2 1.5 1 0 0 1 1 1 0 Tropomyosin like Fzo_mitofusin PF04799.13 CEP08526.1 - 0.03 13.9 6.1 0.073 12.6 6.1 1.6 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.13 CEP08526.1 - 0.038 13.2 2.9 0.069 12.4 2.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein MCPsignal PF00015.21 CEP08526.1 - 0.046 13.5 1.4 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAT PF03417.16 CEP08526.1 - 0.066 12.9 1.3 0.14 11.8 1.3 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Asp2 PF16929.5 CEP08526.1 - 0.26 10.2 2.9 0.41 9.6 2.9 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter KxDL PF10241.9 CEP08526.1 - 0.29 11.5 9.2 1.8 8.9 8.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1980 PF09323.10 CEP08526.1 - 1.2 9.1 4.1 2.5 8.0 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) YlqD PF11068.8 CEP08526.1 - 2 8.8 8.4 5.8 7.3 8.4 1.8 1 0 0 1 1 1 0 YlqD protein Atg14 PF10186.9 CEP08526.1 - 2.3 7.2 13.8 4.1 6.4 13.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 CEP08526.1 - 2.8 7.5 13.6 5.7 6.4 13.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 CEP08526.1 - 3.1 7.8 6.3 1.9 8.5 3.6 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) DUF4570 PF15134.6 CEP08526.1 - 8.9 6.4 14.2 44 4.1 11.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) THOC7 PF05615.13 CEP08526.1 - 9.2 6.5 15.9 0.96 9.7 10.7 2.2 2 0 0 2 2 1 0 Tho complex subunit 7 DNA_pol_A_exo1 PF01612.20 CEP08527.1 - 3.3e-07 30.2 0.1 5.5e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease YccF PF03733.13 CEP08528.1 - 1.2e-13 51.5 8.3 1.2e-13 51.5 8.3 3.6 3 0 0 3 3 3 1 Inner membrane component domain Na_Ca_ex PF01699.24 CEP08528.1 - 2.1e-11 44.0 21.0 3.8e-07 30.2 11.3 3.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF3180 PF11377.8 CEP08528.1 - 5.7 7.1 10.4 6.3 6.9 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) MetOD1 PF18546.1 CEP08534.1 - 0.057 13.4 0.2 0.97 9.4 0.0 2.5 2 0 0 2 2 2 0 Metanogen output domain 1 WD40 PF00400.32 CEP08536.1 - 3.7e-42 141.5 21.6 0.00012 22.8 0.0 11.3 10 1 1 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08536.1 - 1.5e-22 79.7 1.8 0.00098 19.4 0.1 8.5 4 3 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP08536.1 - 2.7e-11 43.7 2.2 0.012 15.5 0.2 4.2 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 CEP08536.1 - 3.3e-06 27.4 1.2 0.71 10.4 0.0 4.6 4 0 0 4 4 4 2 PQQ-like domain WD40_like PF17005.5 CEP08536.1 - 5.2e-05 22.7 6.2 2.7 7.2 0.2 5.0 2 2 2 5 5 5 3 WD40-like domain PQQ_2 PF13360.6 CEP08536.1 - 6.1e-05 22.7 5.3 0.014 15.0 1.3 3.6 2 1 1 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.6 CEP08536.1 - 0.00011 22.1 0.6 8.7 6.4 0.1 4.2 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 CEP08536.1 - 0.0012 17.9 3.3 9.5 5.1 0.0 5.6 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CEP08536.1 - 0.0064 15.6 2.4 0.11 11.5 0.1 2.2 2 0 0 2 2 2 1 Coatomer WD associated region RAB3GAP2_N PF14655.6 CEP08536.1 - 0.012 14.9 0.0 8.8 5.5 0.0 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 CEP08536.1 - 0.037 14.0 2.7 29 4.8 0.0 4.9 4 0 0 4 4 4 0 PQQ enzyme repeat PD40 PF07676.12 CEP08536.1 - 0.11 12.5 2.3 14 5.7 0.1 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 CEP08536.1 - 0.15 10.4 0.0 0.72 8.1 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz VCBS PF13517.6 CEP08536.1 - 1.1 9.9 5.7 3.6 8.3 0.4 4.3 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S19e PF01090.19 CEP08537.1 - 1.4e-56 190.0 0.0 1.5e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CEP08537.1 - 0.12 12.5 0.2 0.28 11.3 0.1 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain E1-E2_ATPase PF00122.20 CEP08538.1 - 6.1e-25 87.8 0.1 9.8e-24 83.9 0.1 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEP08538.1 - 6.5e-07 29.8 0.1 0.0029 17.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP08538.1 - 0.00031 20.4 0.0 0.00088 18.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP08538.1 - 0.12 12.5 0.0 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Cation transport ATPase (P-type) SCA7 PF08313.12 CEP08539.1 - 5.2e-30 103.1 2.1 1.3e-29 101.8 2.1 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain Tachystatin_A PF11406.8 CEP08539.1 - 0.061 13.4 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A SUIM_assoc PF16619.5 CEP08539.1 - 0.25 11.4 6.0 0.061 13.4 0.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GATA PF00320.27 CEP08540.1 - 1.8e-15 56.2 3.9 1.8e-15 56.2 3.9 1.8 2 0 0 2 2 2 1 GATA zinc finger DELLA PF12041.8 CEP08540.1 - 0.0074 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator DELLA protein N terminal Zn-ribbon_8 PF09723.10 CEP08540.1 - 0.14 12.3 0.3 0.28 11.3 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 CEP08540.1 - 0.44 10.4 3.3 2.3 8.1 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DSPc PF00782.20 CEP08542.1 - 1.8e-32 112.0 0.3 1.1e-30 106.2 0.3 2.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP08542.1 - 3.3e-05 23.6 0.0 7.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEP08542.1 - 0.0018 18.4 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 CEP08542.1 - 0.017 15.4 0.0 0.052 13.9 0.0 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain RhoGAP PF00620.27 CEP08544.1 - 5.1e-27 94.6 0.0 1.3e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 CEP08544.1 - 2.3e-26 92.4 0.1 5.4e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 MyTH4 domain Exo_endo_phos_2 PF14529.6 CEP08545.1 - 3.9e-12 46.1 1.3 5.9e-12 45.5 0.2 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase PMBR PF09373.10 CEP08545.1 - 0.17 12.1 0.8 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 Pseudomurein-binding repeat MDMPI_N PF11716.8 CEP08547.1 - 0.11 13.2 0.0 0.33 11.6 0.0 1.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PIG-U PF06728.13 CEP08549.1 - 7.4e-86 288.6 33.8 1.3e-47 162.7 13.7 2.2 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U Dynamin_N PF00350.23 CEP08550.1 - 9e-18 64.9 1.5 4.6e-17 62.6 0.0 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 CEP08550.1 - 2.1e-10 40.7 0.2 7.7e-09 35.6 0.2 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP08550.1 - 6e-08 32.4 0.5 4.8e-05 23.0 0.3 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP08550.1 - 2.6e-05 24.2 0.8 0.61 10.0 0.1 3.5 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CEP08550.1 - 0.0026 17.4 0.1 0.51 9.9 0.1 2.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 CEP08550.1 - 0.014 14.5 0.3 0.099 11.7 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 CEP08550.1 - 0.026 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CEP08550.1 - 0.034 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exo_endo_phos PF03372.23 CEP08550.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cas_Cas2CT1978 PF09707.10 CEP08550.1 - 0.087 12.9 0.8 2.7 8.1 0.0 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) AAA_16 PF13191.6 CEP08550.1 - 0.32 11.4 2.3 4.7 7.6 0.0 3.3 1 1 0 2 2 2 0 AAA ATPase domain ORC6 PF05460.13 CEP08551.1 - 0.092 12.0 3.4 0.11 11.7 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RVT_1 PF00078.27 CEP08553.1 - 4.3e-17 62.4 0.1 5.7e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGDYG PF14083.6 CEP08554.1 - 0.011 15.9 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 PGDYG protein DNA_pol_A_exo1 PF01612.20 CEP08555.1 - 3e-07 30.3 0.0 6.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Phage-A118_gp45 PF10653.9 CEP08555.1 - 0.12 12.5 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 Integrase_H2C2 PF17921.1 CEP08557.1 - 2.9e-10 40.1 0.2 5.2e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP08557.1 - 1.2e-05 25.4 1.7 1.8e-05 24.8 0.8 1.8 2 0 0 2 2 2 1 H2C2 zinc finger rve PF00665.26 CEP08558.1 - 5.8e-16 58.8 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP08558.1 - 1.5e-08 34.6 0.1 2.9e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP08558.1 - 3e-08 33.5 1.3 4e-08 33.0 0.4 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP08558.1 - 3.5e-06 27.1 0.2 9.4e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger DUF1759 PF03564.15 CEP08560.1 - 0.048 13.6 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Vip3A_N PF12495.8 CEP08560.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal gag-asp_proteas PF13975.6 CEP08563.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP08563.1 - 3.9e-05 24.2 0.0 6.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CEP08563.1 - 0.0039 17.5 0.0 0.3 11.4 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP08563.1 - 0.093 12.5 0.2 0.38 10.5 0.2 1.9 1 1 0 1 1 1 0 Aspartyl protease DUF1947 PF09183.10 CEP08564.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Xol-1_GHMP-like PF09109.10 CEP08564.1 - 0.083 12.8 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DivIC PF04977.15 CEP08565.1 - 7.3 6.4 10.2 1.9 8.3 1.4 3.0 2 1 0 2 2 2 0 Septum formation initiator DUF2457 PF10446.9 CEP08566.1 - 4.3 6.4 8.6 4.2 6.4 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Helitron_like_N PF14214.6 CEP08567.1 - 1.3e-25 90.7 0.3 5.3e-25 88.7 0.0 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Spem1 PF15670.5 CEP08567.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 FAR1 PF03101.15 CEP08568.1 - 1.8e-05 25.4 2.1 2.8e-05 24.7 2.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain BrkDBD PF09607.10 CEP08568.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain zf-C2H2_4 PF13894.6 CEP08569.1 - 0.037 14.9 3.0 0.037 14.9 3.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF445 PF04286.12 CEP08569.1 - 0.071 12.9 1.2 0.12 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) zf-C2H2_11 PF16622.5 CEP08569.1 - 0.4 10.5 2.2 0.81 9.5 2.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 CEP08569.1 - 1.3 9.7 9.2 0.32 11.5 3.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type SAPS PF04499.15 CEP08569.1 - 1.3 7.7 9.5 4.5 5.9 5.6 2.3 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4499 PF14934.6 CEP08570.1 - 8.4e-14 51.7 0.5 1.6e-13 50.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 CEP08570.1 - 2.5e-06 28.0 0.0 4.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Ribosomal_L38e PF01781.18 CEP08571.1 - 9.6e-35 118.5 2.1 1e-34 118.4 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 CEP08571.1 - 0.046 13.9 0.1 0.053 13.8 0.1 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain RNA_pol_Rbc25 PF08292.12 CEP08572.1 - 8.3e-39 132.8 0.0 1.1e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CEP08572.1 - 7.7e-18 64.6 0.2 1.4e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CEP08572.1 - 0.0093 16.3 0.1 0.022 15.1 0.1 1.8 1 1 0 1 1 1 1 S1 RNA binding domain DUF273 PF03314.14 CEP08572.1 - 0.055 13.0 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Pkinase PF00069.25 CEP08573.1 - 2.6e-29 102.4 0.0 4.4e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08573.1 - 7.5e-17 61.5 0.0 1.2e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP08573.1 - 1.1e-08 34.3 0.0 2.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase UBA PF00627.31 CEP08573.1 - 0.00069 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain APH PF01636.23 CEP08573.1 - 0.011 15.6 0.0 0.13 12.1 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 CEP08573.1 - 0.054 13.7 0.4 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 CEP08573.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 CEP08574.1 - 8.2e-10 39.3 0.1 5.1e-08 33.5 0.1 2.1 1 1 0 1 1 1 1 SET domain DEAD PF00270.29 CEP08575.1 - 2.2e-47 161.1 0.1 4.5e-47 160.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP08575.1 - 6.2e-25 87.7 0.0 7.2e-24 84.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEP08575.1 - 7.7e-20 70.9 0.1 1.9e-19 69.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEP08575.1 - 1.5e-07 31.6 0.0 1.5e-07 31.6 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 CEP08576.1 - 6.7e-65 215.1 0.9 5.3e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PMI_typeI PF01238.21 CEP08577.1 - 8.4e-73 245.7 0.0 1e-72 245.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 CEP08577.1 - 0.0088 15.7 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain PMI_typeI PF01238.21 CEP08578.1 - 1.5e-42 146.1 0.0 1.7e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I GATA PF00320.27 CEP08579.1 - 1.3e-14 53.5 7.2 1.3e-14 53.5 7.2 1.9 2 0 0 2 2 2 1 GATA zinc finger PAS_3 PF08447.12 CEP08579.1 - 1.5e-14 54.0 0.0 2.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CEP08579.1 - 2.6e-07 30.6 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 CEP08579.1 - 4.6e-05 23.6 0.0 7.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CEP08579.1 - 6.4e-05 23.2 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 CEP08579.1 - 0.0019 18.3 0.0 0.0019 18.3 0.0 2.3 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 CEP08579.1 - 0.054 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS domain Peptidase_S10 PF00450.22 CEP08580.1 - 1.5e-125 419.9 0.7 1.9e-125 419.6 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sec7 PF01369.20 CEP08581.1 - 7.2e-65 218.1 0.1 1.4e-64 217.2 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEP08581.1 - 2.3e-19 69.8 0.2 6.9e-18 65.1 0.0 3.4 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF-hand_4 PF12763.7 CEP08584.1 - 2e-31 108.0 0.0 1.3e-12 47.6 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand Tmemb_14 PF03647.13 CEP08584.1 - 9.8e-18 64.7 1.8 9.8e-18 64.7 1.8 2.0 2 0 0 2 2 2 1 Transmembrane proteins 14C EF-hand_1 PF00036.32 CEP08584.1 - 3.8e-14 51.1 1.8 0.021 14.4 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEP08584.1 - 4.1e-12 46.4 1.4 0.00024 21.5 0.2 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEP08584.1 - 6.7e-10 38.1 1.5 0.23 11.5 0.1 5.3 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CEP08584.1 - 0.0011 18.8 0.2 2.9 7.8 0.0 4.3 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.6 CEP08584.1 - 0.023 14.2 0.0 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 EF hand DUF572 PF04502.13 CEP08584.1 - 0.032 13.9 4.1 0.05 13.2 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rootletin PF15035.6 CEP08584.1 - 0.092 12.8 10.1 0.17 11.9 10.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Eaf7 PF07904.13 CEP08584.1 - 0.83 10.1 3.4 2.2 8.7 3.4 1.7 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Sugarporin_N PF11471.8 CEP08584.1 - 4.9 7.2 8.5 39 4.3 0.1 3.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DZR PF12773.7 CEP08585.1 - 0.086 12.9 0.4 0.28 11.2 0.4 1.8 1 0 0 1 1 1 0 Double zinc ribbon Tafi-CsgC PF10610.9 CEP08586.1 - 0.023 14.9 0.6 0.17 12.1 0.3 2.4 2 0 0 2 2 2 0 Thin aggregative fimbriae synthesis protein HTH_28 PF13518.6 CEP08587.1 - 0.003 17.6 0.1 0.0046 17.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sugar_tr PF00083.24 CEP08588.1 - 1e-53 182.8 22.6 1.3e-53 182.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP08588.1 - 1.7e-22 79.9 34.2 4.4e-14 52.2 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CEP08590.1 - 0.33 11.3 0.0 0.33 11.3 0.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) SH3_9 PF14604.6 CEP08591.1 - 4.2e-11 42.5 0.0 6.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP08591.1 - 6.3e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain VSP PF03302.13 CEP08591.1 - 1.5e-06 27.4 5.4 2.4e-06 26.7 5.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SH3_2 PF07653.17 CEP08591.1 - 0.00069 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.6 CEP08591.1 - 0.0024 16.8 0.2 0.0024 16.8 0.2 1.7 1 1 1 2 2 2 1 Amnionless EphA2_TM PF14575.6 CEP08591.1 - 0.038 14.9 0.7 0.095 13.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 CEP08591.1 - 0.043 13.2 0.6 0.13 11.7 0.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4064 PF13273.6 CEP08591.1 - 0.08 13.2 2.7 0.17 12.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Plasmodium_Vir PF05795.11 CEP08591.1 - 0.73 9.2 9.9 0.23 10.8 6.2 1.8 1 1 1 2 2 2 0 Plasmodium vivax Vir protein zf-C2H2 PF00096.26 CEP08592.1 - 2e-06 28.0 11.8 0.0068 16.8 0.9 3.8 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CEP08592.1 - 2.3e-05 24.6 7.7 0.012 15.7 0.7 2.9 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CEP08592.1 - 0.0013 19.4 13.7 0.041 14.7 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP08592.1 - 4.9 7.8 15.9 0.41 11.2 0.6 3.2 3 1 0 3 3 3 0 Zinc-finger double domain CBF PF03914.17 CEP08593.1 - 1.7e-52 177.9 0.3 1.7e-52 177.9 0.3 3.9 4 0 0 4 4 4 2 CBF/Mak21 family Cnd1 PF12717.7 CEP08593.1 - 4.7e-05 23.5 2.3 4.7e-05 23.5 2.3 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Ion_trans PF00520.31 CEP08594.1 - 6.6e-138 457.8 102.7 2e-45 155.0 18.2 4.2 4 0 0 4 4 4 4 Ion transport protein CPSase_L_D2 PF02786.17 CEP08596.1 - 9.6e-112 371.6 0.2 3.7e-83 278.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CEP08596.1 - 3.3e-49 166.0 0.0 6.9e-49 164.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEP08596.1 - 3.3e-46 157.5 0.0 3e-45 154.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CEP08596.1 - 8.7e-45 152.4 0.0 1.9e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CEP08596.1 - 5e-40 136.6 0.0 2.2e-39 134.5 0.0 2.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CEP08596.1 - 1.6e-33 116.0 0.1 5.5e-33 114.3 0.1 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CEP08596.1 - 1.1e-18 67.2 0.0 5.9e-18 64.9 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CEP08596.1 - 2.6e-15 56.5 0.9 2.3e-07 30.6 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEP08596.1 - 2.6e-13 49.9 0.1 3.1e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CEP08596.1 - 1.3e-09 37.9 0.0 0.00021 21.1 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CEP08596.1 - 0.00012 21.9 0.2 0.013 15.2 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CEP08596.1 - 0.0002 21.2 0.1 0.75 9.6 0.0 4.7 5 0 0 5 5 5 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 CEP08596.1 - 0.00062 19.8 0.3 0.58 10.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GSH-S_ATP PF02955.16 CEP08596.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DcpS_C PF11969.8 CEP08597.1 - 1.5e-27 96.3 0.0 2.6e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CEP08597.1 - 5.8e-23 81.7 0.0 9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal IBR PF01485.21 CEP08598.1 - 6.5e-08 32.7 11.9 6.5e-08 32.7 11.9 5.3 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CEP08598.1 - 0.028 14.7 9.4 0.028 14.7 9.4 5.3 4 1 1 5 5 5 0 Ring finger domain PcfK PF14058.6 CEP08598.1 - 3.9 7.8 7.8 7.4 6.9 0.4 2.3 2 0 0 2 2 2 0 PcfK-like protein DUF2967 PF11179.8 CEP08598.1 - 5.4 5.0 6.7 8.1 4.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Pkinase PF00069.25 CEP08599.1 - 4.5e-74 249.1 0.0 7.6e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08599.1 - 1.1e-38 133.0 0.0 1.7e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP08599.1 - 5.5e-05 23.2 0.0 0.0068 16.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP08599.1 - 0.094 12.3 1.5 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase V-SNARE PF05008.15 CEP08600.1 - 0.34 11.3 4.6 0.74 10.2 3.3 2.3 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ADP_ribosyl_GH PF03747.14 CEP08601.1 - 2.3e-47 162.2 0.0 2.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Forkhead PF00250.18 CEP08602.1 - 1.1e-17 64.0 0.2 1.6e-15 57.1 0.2 2.3 1 1 0 1 1 1 1 Forkhead domain Pkinase PF00069.25 CEP08603.1 - 6.5e-70 235.5 0.0 7.9e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08603.1 - 4.6e-34 117.9 0.0 6.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CEP08603.1 - 8.5e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CEP08603.1 - 0.0047 16.3 0.3 0.26 10.6 0.0 2.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEP08603.1 - 0.0088 15.0 0.1 0.052 12.5 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain p450 PF00067.22 CEP08604.1 - 2.2e-64 217.9 0.0 9.7e-64 215.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Prefoldin_2 PF01920.20 CEP08604.1 - 7.6e-23 80.5 12.7 1.8e-22 79.3 12.7 1.7 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.9 CEP08604.1 - 0.033 14.5 10.9 0.057 13.7 1.6 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4795 PF16043.5 CEP08604.1 - 0.08 12.5 11.6 0.22 11.1 11.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 CEP08604.1 - 0.089 12.8 2.5 0.76 9.8 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II PI3K_P85_iSH2 PF16454.5 CEP08604.1 - 0.11 12.1 9.6 1.1 8.8 9.6 2.4 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LPD25 PF18840.1 CEP08604.1 - 0.25 11.9 4.1 0.43 11.1 3.1 1.9 1 1 0 1 1 1 0 Large polyvalent protein associated domain 25 Tup_N PF08581.10 CEP08604.1 - 0.41 11.0 9.4 0.35 11.2 0.9 3.8 4 0 0 4 4 4 0 Tup N-terminal DUF5082 PF16888.5 CEP08604.1 - 0.43 10.8 7.0 6.5 7.0 7.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CEP08604.1 - 0.52 10.8 2.9 17 5.9 0.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GvpK PF05121.12 CEP08604.1 - 1.5 8.9 7.1 0.26 11.4 0.4 2.8 3 0 0 3 3 3 0 Gas vesicle protein K AKNA PF12443.8 CEP08604.1 - 2.6 8.7 4.6 2.4 8.9 0.5 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.15 CEP08604.1 - 3.5 7.5 10.6 1.3 8.8 2.9 2.7 2 0 0 2 2 2 0 Septum formation initiator Rho_Binding PF08912.11 CEP08604.1 - 5.4 7.9 12.8 7.3 7.5 1.3 2.9 2 0 0 2 2 2 0 Rho Binding XhlA PF10779.9 CEP08604.1 - 5.5 7.3 8.7 5.3 7.3 1.8 2.7 2 0 0 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 CEP08604.1 - 9.5 6.7 7.1 5.1 7.6 1.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Nfu_N PF08712.11 CEP08605.1 - 2.4e-31 107.6 0.0 8.2e-31 105.9 0.0 1.9 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CEP08605.1 - 3.1e-28 97.7 0.1 5e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 CEP08605.1 - 0.0051 16.9 0.2 0.016 15.3 0.2 1.8 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Pex24p PF06398.11 CEP08606.1 - 1.4e-20 73.7 10.8 2.1e-20 73.0 10.8 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ISPD_C PF18706.1 CEP08606.1 - 0.0085 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain MCM PF00493.23 CEP08607.1 - 6.4e-101 336.1 0.0 1.4e-100 335.0 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain tRNA-synt_1d PF00750.19 CEP08607.1 - 6e-87 291.8 3.5 6e-87 291.8 3.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) MCM_OB PF17207.3 CEP08607.1 - 6.9e-35 119.7 0.1 1.4e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEP08607.1 - 6.3e-27 93.8 2.5 2.2e-26 92.1 2.5 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain DALR_1 PF05746.15 CEP08607.1 - 6.4e-25 87.6 0.0 2.1e-24 85.9 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain MCM_N PF14551.6 CEP08607.1 - 3.8e-16 59.6 0.4 1.4e-15 57.7 0.4 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEP08607.1 - 3.9e-05 23.1 0.0 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEP08607.1 - 0.00012 22.1 0.0 0.0004 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CEP08607.1 - 0.00063 19.6 0.0 0.004 17.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2108 PF09881.9 CEP08609.1 - 0.075 13.0 1.3 0.18 11.8 1.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) DUF347 PF03988.12 CEP08609.1 - 2.3 8.5 6.5 0.45 10.8 0.2 2.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) SAYSvFN PF10260.9 CEP08609.1 - 2.8 7.9 6.3 1.5 8.8 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) CrgA PF06781.12 CEP08609.1 - 6.6 6.9 9.5 5 7.2 0.1 3.6 4 0 0 4 4 4 0 Cell division protein CrgA HAD_2 PF13419.6 CEP08610.1 - 1.6e-24 86.9 0.1 1.9e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP08610.1 - 6.5e-11 42.9 0.1 6.6e-10 39.6 0.0 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP08610.1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PIF1 PF05970.14 CEP08612.1 - 5.3e-57 193.6 3.3 8.8e-32 110.7 0.0 2.5 2 1 1 3 3 3 2 PIF1-like helicase DUF4939 PF16297.5 CEP08613.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RVP_2 PF08284.11 CEP08614.1 - 7.4e-07 29.0 0.1 1.6e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 CEP08614.1 - 0.0014 18.5 0.1 0.0036 17.2 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEP08614.1 - 0.033 14.3 2.0 0.06 13.4 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4187 PF13821.6 CEP08614.1 - 0.044 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) KilA-N PF04383.13 CEP08617.1 - 0.002 17.9 0.0 0.012 15.4 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.21 CEP08618.1 - 6.8e-59 199.5 0.0 8.3e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_46 PF01374.18 CEP08619.1 - 3.6e-41 141.1 0.1 5.6e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 MutS_V PF00488.21 CEP08620.1 - 4.9e-83 277.8 0.4 8.2e-83 277.1 0.4 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEP08620.1 - 1.3e-37 129.9 1.1 1.3e-37 129.9 1.1 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 CEP08620.1 - 4.8e-17 62.5 0.7 2.7e-16 60.1 0.1 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CEP08620.1 - 6.1e-14 52.1 2.2 6.1e-14 52.1 2.2 3.1 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 CEP08620.1 - 5.3e-09 36.3 0.1 1.3e-08 35.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain I HEPN_RnaseLS PF18869.1 CEP08620.1 - 0.0087 16.2 0.3 0.46 10.6 0.1 2.5 2 0 0 2 2 2 1 RnaseLS-like HEPN AAA_27 PF13514.6 CEP08620.1 - 0.0093 15.6 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain PTS-HPr PF00381.19 CEP08621.1 - 3.8e-15 55.9 0.0 4.2e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Aa_trans PF01490.18 CEP08622.1 - 9.6e-78 261.7 35.8 1.1e-77 261.5 35.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1600 PF07667.11 CEP08622.1 - 6.6 7.0 20.1 0.78 10.0 0.8 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1600) ICL PF00463.21 CEP08623.1 - 1.5e-264 878.4 2.3 1.7e-264 878.2 2.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CEP08623.1 - 9.6e-09 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Humanin PF15040.6 CEP08624.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Humanin family M16C_assoc PF08367.11 CEP08625.1 - 1.4e-80 270.1 0.2 2.8e-80 269.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CEP08625.1 - 2.2e-30 106.0 0.0 1.6e-22 80.4 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEP08625.1 - 9.6e-09 35.4 0.1 1.3e-06 28.5 0.0 3.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) BORCS6 PF10157.9 CEP08625.1 - 0.02 15.1 0.0 0.076 13.2 0.0 1.9 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 NETI PF14044.6 CEP08625.1 - 0.026 14.2 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 NETI protein DUF2312 PF10073.9 CEP08625.1 - 0.17 11.5 6.2 1.3 8.7 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Xan_ur_permease PF00860.20 CEP08626.1 - 5.5e-56 189.9 33.8 9.1e-55 185.9 33.8 2.1 1 1 0 1 1 1 1 Permease family dCMP_cyt_deam_1 PF00383.23 CEP08627.1 - 5.2e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP08627.1 - 8e-09 35.4 0.1 3.6e-08 33.2 0.1 1.8 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CEP08627.1 - 0.00092 19.3 0.7 0.0034 17.4 0.7 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase DUF1065 PF06358.11 CEP08627.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) DIOX_N PF14226.6 CEP08628.1 - 9.8e-21 74.7 0.0 1.9e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEP08628.1 - 2.5e-14 53.6 0.0 5.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.29 CEP08629.1 - 1.4e-51 174.4 0.0 2.1e-41 141.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP08629.1 - 5.3e-14 51.7 0.2 2.9e-09 36.6 0.4 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEP08629.1 - 1.8e-11 44.7 0.1 0.0013 19.2 0.1 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CEP08629.1 - 3.9e-07 30.4 1.1 0.11 12.8 0.1 3.8 2 2 1 3 3 3 2 AAA domain ABC_tran PF00005.27 CEP08629.1 - 1.4e-06 28.8 0.1 0.018 15.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter DUF815 PF05673.13 CEP08629.1 - 3.8e-06 26.2 0.0 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 CEP08629.1 - 5.3e-06 26.5 0.3 0.11 12.4 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 CEP08629.1 - 5.4e-06 26.4 0.4 0.094 12.6 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Rad17 PF03215.15 CEP08629.1 - 5.6e-06 26.4 0.0 0.0017 18.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 CEP08629.1 - 2.8e-05 24.1 0.0 0.0069 16.3 0.0 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEP08629.1 - 3e-05 24.6 0.1 0.5 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEP08629.1 - 3.4e-05 23.8 0.4 0.12 12.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 CEP08629.1 - 3.9e-05 23.3 0.2 0.03 13.8 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CEP08629.1 - 4.6e-05 23.6 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEP08629.1 - 4.7e-05 23.4 0.4 0.1 12.6 0.0 2.7 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CEP08629.1 - 7.7e-05 22.7 0.0 0.021 14.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CEP08629.1 - 0.00011 22.5 0.1 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 CEP08629.1 - 0.00013 22.1 0.0 0.042 14.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_29 PF13555.6 CEP08629.1 - 0.0002 21.0 0.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RuvB_N PF05496.12 CEP08629.1 - 0.00023 20.9 0.1 0.067 12.9 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 CEP08629.1 - 0.00039 20.2 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 CEP08629.1 - 0.00043 19.6 0.1 0.054 12.7 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CEP08629.1 - 0.0007 19.0 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CEP08629.1 - 0.0013 18.5 0.5 2 8.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 CEP08629.1 - 0.0014 18.5 0.0 0.83 9.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.9 CEP08629.1 - 0.0017 18.1 0.3 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 CEP08629.1 - 0.0022 17.9 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEP08629.1 - 0.0033 18.0 0.0 0.78 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEP08629.1 - 0.0035 17.1 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 CEP08629.1 - 0.0036 16.7 0.1 0.61 9.4 0.0 2.4 2 0 0 2 2 2 1 KaiC SRPRB PF09439.10 CEP08629.1 - 0.0062 16.0 0.1 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 CEP08629.1 - 0.014 15.1 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CEP08629.1 - 0.025 14.8 0.2 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 CEP08629.1 - 0.026 13.3 2.4 0.031 13.1 0.1 2.1 3 0 0 3 3 3 0 Adenovirus IVa2 protein NB-ARC PF00931.22 CEP08629.1 - 0.033 13.4 1.3 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 CEP08629.1 - 0.045 13.2 0.1 5.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 CEP08629.1 - 0.052 12.8 0.2 1.2 8.3 0.0 2.6 2 1 1 3 3 3 0 Septin AFG1_ATPase PF03969.16 CEP08629.1 - 0.056 12.3 0.1 1.2 8.0 0.0 2.6 2 1 0 2 2 2 0 AFG1-like ATPase Roc PF08477.13 CEP08629.1 - 0.065 13.4 0.6 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 CEP08629.1 - 0.066 13.1 0.5 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CEP08629.1 - 0.075 12.9 0.5 7.3 6.5 0.2 2.4 2 0 0 2 2 2 0 NTPase CPT PF07931.12 CEP08629.1 - 0.12 12.2 0.4 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 CEP08629.1 - 0.15 12.4 0.4 32 4.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CEP08629.1 - 0.21 11.0 0.4 28 4.0 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RhoGAP PF00620.27 CEP08630.1 - 9.3e-26 90.5 0.4 4.5e-15 55.8 0.1 2.9 2 1 1 3 3 3 2 RhoGAP domain FCH PF00611.23 CEP08630.1 - 5.5e-15 55.4 0.3 1.9e-14 53.7 0.3 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SVIP PF15811.5 CEP08631.1 - 7.3e-07 29.6 8.0 7.9e-07 29.4 1.6 2.2 1 1 1 2 2 2 2 Small VCP/p97-interacting protein WLM PF08325.10 CEP08631.1 - 0.016 15.3 0.6 0.024 14.7 0.6 1.3 1 0 0 1 1 1 0 WLM domain Mito_carr PF00153.27 CEP08632.1 - 3.4e-63 209.6 3.9 4.2e-22 77.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CEP08632.1 - 2.5e-05 24.6 5.5 0.017 15.5 0.1 2.7 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family DUF2043 PF09740.9 CEP08633.1 - 8.9e-28 97.1 0.5 3.4e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) DUF5578 PF17741.1 CEP08633.1 - 0.07 12.5 0.6 0.76 9.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5578) Aldo_ket_red PF00248.21 CEP08634.1 - 1.7e-54 185.0 0.0 6.5e-54 183.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family SAP18 PF06487.12 CEP08634.1 - 8.3e-36 123.2 0.0 1.4e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DEDD_Tnp_IS110 PF01548.17 CEP08634.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Transposase Recep_L_domain PF01030.24 CEP08635.1 - 8.1e-10 38.8 12.1 0.00069 19.7 0.7 4.7 1 1 3 5 5 5 4 Receptor L domain LRR_5 PF13306.6 CEP08635.1 - 0.0027 17.7 0.4 0.9 9.5 0.0 3.4 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ribosomal_L10 PF00466.20 CEP08636.1 - 8e-12 45.2 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4147 PF13660.6 CEP08636.1 - 0.062 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DASH_Dad3 PF08656.10 CEP08636.1 - 0.13 12.4 0.5 0.31 11.2 0.0 1.9 2 1 0 2 2 2 0 DASH complex subunit Dad3 Peptidase_C97 PF05903.14 CEP08637.1 - 2.7e-20 72.8 0.4 3.6e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 PPPDE putative peptidase domain GRAB PF10375.9 CEP08638.1 - 2e-07 30.6 0.4 2e-07 30.6 0.4 2.3 2 0 0 2 2 2 1 GRIP-related Arf-binding domain ADIP PF11559.8 CEP08638.1 - 0.0002 21.5 13.3 0.0002 21.5 13.3 6.8 2 2 4 6 6 6 3 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CEP08638.1 - 0.0015 19.1 25.0 0.0015 19.1 25.0 4.3 1 1 3 4 4 4 1 Fez1 Filament PF00038.21 CEP08638.1 - 0.0016 18.1 96.4 0.0067 16.0 29.2 4.8 1 1 3 5 5 5 4 Intermediate filament protein Seryl_tRNA_N PF02403.22 CEP08638.1 - 0.0019 18.4 18.3 0.0019 18.4 18.3 7.5 3 1 4 7 7 7 1 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 CEP08638.1 - 0.013 15.6 10.5 0.013 15.6 10.5 6.7 2 2 4 6 6 5 0 Laminin Domain II GRIP PF01465.20 CEP08638.1 - 0.019 14.8 0.0 0.078 12.9 0.0 2.1 1 0 0 1 1 1 0 GRIP domain Fib_alpha PF08702.10 CEP08638.1 - 0.097 12.9 82.3 0.11 12.6 12.8 6.7 2 2 3 6 6 6 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CEP08638.1 - 0.76 9.8 55.1 0.17 12.0 3.7 6.4 2 2 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CEP08638.1 - 2 8.4 69.7 0.079 13.0 7.8 7.4 2 2 7 9 9 9 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 CEP08638.1 - 2.2 5.7 100.0 0.44 8.0 21.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) PLAC9 PF15205.6 CEP08638.1 - 5.4 7.5 10.7 6.7 7.2 0.2 4.4 3 1 1 4 4 4 0 Placenta-specific protein 9 UBA2_C PF16195.5 CEP08639.1 - 0.045 14.4 3.8 0.074 13.7 3.8 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus QueF PF14489.6 CEP08639.1 - 0.057 13.6 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 QueF-like protein DUF4286 PF14114.6 CEP08640.1 - 0.063 13.8 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Peptidase_C98 PF15499.6 CEP08642.1 - 0.013 15.0 0.2 0.013 15.0 0.2 1.7 1 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-Dof PF02701.15 CEP08642.1 - 0.087 13.0 0.9 0.087 13.0 0.9 2.6 3 0 0 3 3 3 0 Dof domain, zinc finger zf-C2HC_2 PF13913.6 CEP08642.1 - 0.092 12.7 0.7 0.092 12.7 0.7 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1 PF03811.13 CEP08642.1 - 0.12 12.2 0.6 0.12 12.2 0.6 2.4 3 0 0 3 3 3 0 InsA N-terminal domain Zn_Tnp_IS1595 PF12760.7 CEP08642.1 - 0.22 11.6 9.0 0.39 10.7 1.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 CEP08642.1 - 1.5 8.9 13.8 6 7.0 2.5 3.4 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like PHD PF00628.29 CEP08642.1 - 2.4 8.1 11.6 9.9 6.1 1.6 2.9 2 2 0 2 2 2 0 PHD-finger zf-C2H2_4 PF13894.6 CEP08642.1 - 3.5 8.7 9.4 7.3 7.7 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Na_Ca_ex PF01699.24 CEP08644.1 - 0.00021 21.2 3.4 0.00027 20.9 3.4 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein SLATT_5 PF18160.1 CEP08644.1 - 0.034 13.5 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 SPC25 PF06703.11 CEP08644.1 - 0.086 12.6 1.4 0.13 12.0 1.4 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3792 PF12670.7 CEP08644.1 - 0.11 12.6 2.4 0.17 12.0 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DUF997 PF06196.12 CEP08644.1 - 2.7 8.1 7.6 0.94 9.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Chitin_synth_2 PF03142.15 CEP08645.1 - 4.8e-239 794.4 1.4 7.7e-239 793.7 1.4 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP08645.1 - 6.2e-79 266.0 0.1 2.5e-49 168.1 0.1 3.2 2 1 1 3 3 3 3 Myosin head (motor domain) DEK_C PF08766.11 CEP08645.1 - 5.9e-19 67.7 0.7 6.7e-18 64.4 1.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CEP08645.1 - 2.3e-15 56.5 0.1 2e-09 37.4 0.0 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CEP08645.1 - 1.1e-12 48.3 2.7 1.1e-12 48.3 2.7 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP08645.1 - 2.5e-12 47.2 0.0 1.8e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEP08645.1 - 9.4e-06 25.5 0.0 0.015 15.1 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP08645.1 - 0.014 14.9 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 21 T2SSE PF00437.20 CEP08645.1 - 0.036 13.1 0.0 0.086 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 CEP08645.1 - 0.093 12.8 0.3 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 CEP08645.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family CAP_N PF01213.19 CEP08645.1 - 0.74 9.2 7.4 2 7.8 7.4 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_16 PF13191.6 CEP08645.1 - 1.4 9.3 4.3 0.56 10.6 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain Secretin_N_2 PF07655.13 CEP08645.1 - 2 9.0 12.4 3.7 8.1 6.5 3.1 2 1 0 2 2 2 0 Secretin N-terminal domain MULE PF10551.9 CEP08646.1 - 0.01 16.3 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 0 MULE transposase domain WRKY PF03106.15 CEP08646.1 - 0.058 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 WRKY DNA -binding domain FAR1 PF03101.15 CEP08646.1 - 0.1 13.3 0.4 0.36 11.6 0.2 2.0 2 0 0 2 2 2 0 FAR1 DNA-binding domain MULE PF10551.9 CEP08648.1 - 2.2e-27 95.3 0.1 8.4e-27 93.4 0.1 2.1 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 CEP08648.1 - 3.6e-07 30.8 1.4 3.6e-07 30.8 1.4 3.0 3 0 0 3 3 3 1 FAR1 DNA-binding domain Transposase_mut PF00872.18 CEP08648.1 - 0.00061 18.7 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Transposase, Mutator family Sec23_trunk PF04811.15 CEP08649.1 - 6.9e-58 196.1 0.0 2e-56 191.3 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEP08649.1 - 1.8e-19 69.5 0.0 4.7e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEP08649.1 - 2e-17 63.7 0.0 4.8e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEP08649.1 - 9.3e-15 54.4 1.9 2.7e-14 52.9 1.9 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEP08649.1 - 2e-08 34.0 0.0 7.7e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CEP08649.1 - 0.0054 16.1 0.2 0.014 14.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 CEP08649.1 - 0.053 14.2 0.1 11 6.7 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain Myb_DNA-binding PF00249.31 CEP08651.1 - 0.00037 20.6 0.5 0.00085 19.5 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4019 PF13211.6 CEP08651.1 - 0.12 12.7 3.7 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) ApoB100_C PF12491.8 CEP08652.1 - 0.014 15.4 0.8 0.093 12.7 0.0 2.9 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal Peptidase_Prp PF04327.12 CEP08652.1 - 6.1 7.2 5.8 1.6 9.0 0.4 2.9 2 0 0 2 2 2 0 Cysteine protease Prp RVT_1 PF00078.27 CEP08653.1 - 9.6e-05 22.0 0.0 0.00023 20.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) FGGY_C PF02782.16 CEP08656.1 - 2.6e-65 219.9 2.5 1e-64 218.0 1.6 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CEP08656.1 - 7.2e-56 189.5 0.0 1.4e-55 188.5 0.0 1.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain MutS_V PF00488.21 CEP08657.1 - 2.5e-42 145.0 0.5 1.3e-41 142.7 0.1 2.3 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CEP08657.1 - 9.6e-24 84.7 0.3 2.3e-23 83.4 0.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CEP08657.1 - 0.02 15.2 0.0 0.081 13.3 0.0 2.1 2 0 0 2 2 2 0 MutS family domain IV Flavi_NS2B PF01002.19 CEP08657.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B AAA PF00004.29 CEP08658.1 - 1.3e-54 184.2 0.1 5.4e-39 133.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP08658.1 - 1.4e-11 44.0 0.1 3.7e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CEP08658.1 - 2.5e-09 37.5 0.1 1.3e-06 28.7 0.1 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 CEP08658.1 - 1.5e-08 34.7 0.0 4.8e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CEP08658.1 - 2.9e-08 33.6 0.1 0.0032 17.2 0.1 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEP08658.1 - 3.4e-08 34.1 0.2 0.0092 16.5 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.6 CEP08658.1 - 4.7e-08 33.6 1.2 0.01 16.2 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CEP08658.1 - 7.5e-08 32.7 0.6 0.00042 20.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 CEP08658.1 - 1e-07 31.5 0.1 0.013 14.7 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 CEP08658.1 - 2.9e-07 30.1 0.2 5.9e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CEP08658.1 - 1.1e-06 28.7 0.6 0.0016 18.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEP08658.1 - 2.1e-06 27.3 0.2 0.0047 16.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEP08658.1 - 2.2e-06 27.7 2.1 0.064 13.2 0.1 3.6 3 1 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 CEP08658.1 - 5.2e-06 26.3 0.3 0.022 14.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEP08658.1 - 8.8e-06 25.6 0.0 0.077 12.7 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein TsaE PF02367.17 CEP08658.1 - 1.1e-05 25.4 0.0 0.048 13.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CEP08658.1 - 2.1e-05 24.9 0.0 0.027 14.9 0.0 3.1 4 0 0 4 4 2 1 RNA helicase AAA_33 PF13671.6 CEP08658.1 - 3e-05 24.2 0.0 0.29 11.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEP08658.1 - 3.1e-05 23.7 0.1 0.38 10.4 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 CEP08658.1 - 3.2e-05 23.5 0.8 0.022 14.3 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region PhoH PF02562.16 CEP08658.1 - 9.2e-05 22.0 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 CEP08658.1 - 0.00016 21.8 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEP08658.1 - 0.0003 20.6 0.7 0.29 10.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain ATPase PF06745.13 CEP08658.1 - 0.00034 20.0 0.7 0.015 14.7 0.0 2.8 2 1 1 3 3 3 1 KaiC ATPase_2 PF01637.18 CEP08658.1 - 0.00066 19.7 0.7 8.3 6.2 0.0 4.0 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CEP08658.1 - 0.0008 19.9 1.6 0.17 12.4 0.1 3.1 3 0 0 3 3 2 1 ABC transporter NB-ARC PF00931.22 CEP08658.1 - 0.00083 18.6 0.3 1.4 8.0 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain T2SSE PF00437.20 CEP08658.1 - 0.0083 15.2 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.11 CEP08658.1 - 0.0098 15.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEP08658.1 - 0.01 15.4 5.0 1.6 8.2 0.0 4.3 4 1 0 5 5 5 0 AAA domain AAA_19 PF13245.6 CEP08658.1 - 0.012 15.9 2.9 1 9.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain Parvo_NS1 PF01057.17 CEP08658.1 - 0.017 14.2 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 CEP08658.1 - 0.017 15.1 0.1 5.3 7.0 0.0 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CEP08658.1 - 0.024 14.4 0.1 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CEP08658.1 - 0.028 14.1 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 CEP08658.1 - 0.031 14.5 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 CEP08658.1 - 0.05 13.6 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF2075 PF09848.9 CEP08658.1 - 0.054 12.7 0.3 4.9 6.3 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 CEP08658.1 - 0.058 13.2 0.1 1.5 8.7 0.0 2.7 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 CEP08658.1 - 0.073 12.8 0.1 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEP08658.1 - 0.092 12.0 0.2 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 CEP08658.1 - 0.61 9.8 2.3 54 3.5 0.1 4.0 2 2 2 5 5 5 0 DEAD/DEAH box helicase NRDE-2 PF08424.10 CEP08659.1 - 2.3e-06 26.9 4.5 0.00021 20.6 0.9 3.6 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CEP08659.1 - 1.7e-05 25.2 8.7 0.67 10.9 1.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat Suf PF05843.14 CEP08659.1 - 5.2e-05 23.4 0.0 0.084 12.8 0.0 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CEP08659.1 - 0.00017 22.0 1.5 0.019 15.5 1.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP08659.1 - 0.0016 18.4 2.6 0.082 13.1 1.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP08659.1 - 0.029 15.0 2.2 0.029 15.0 2.2 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP08659.1 - 0.1 13.2 2.7 35 5.3 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP08659.1 - 0.14 12.4 4.1 1.7 9.0 2.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEP08659.1 - 0.97 9.6 4.5 3.4 7.9 0.5 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat BOFC_N PF08977.10 CEP08659.1 - 2.4 8.2 4.7 9.2 6.3 0.4 3.5 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal HAT PF02184.16 CEP08659.1 - 2.5 8.2 11.6 4.8 7.2 0.2 4.9 5 2 0 5 5 5 0 HAT (Half-A-TPR) repeat KAR9 PF08580.10 CEP08660.1 - 0.55 8.7 6.6 0.61 8.6 6.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RT_RNaseH PF17917.1 CEP08661.1 - 1e-28 99.7 0.0 2.6e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP08661.1 - 3e-28 97.8 0.1 3.9e-13 49.3 0.1 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08661.1 - 1.4e-09 37.8 0.1 2.4e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP08662.1 - 7.5e-27 94.3 0.0 1.5e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP08662.1 - 1.3e-12 47.6 0.1 6.6e-12 45.3 0.1 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TBCC_N PF16752.5 CEP08662.1 - 0.18 12.3 2.7 2 8.8 2.7 2.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain PIF1 PF05970.14 CEP08663.1 - 3.2e-19 69.3 0.0 5.1e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP08663.1 - 8.6e-16 58.2 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP08663.1 - 1.7e-08 34.9 0.0 3.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP08663.1 - 0.0016 18.7 0.0 0.0046 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP08663.1 - 0.0074 16.1 0.0 0.026 14.3 0.0 2.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CEP08663.1 - 0.017 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CEP08663.1 - 0.09 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_10 PF12846.7 CEP08663.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Exo70 PF03081.15 CEP08664.1 - 3e-81 273.4 1.8 3e-81 273.4 1.8 3.6 4 0 0 4 4 4 1 Exo70 exocyst complex subunit BP28CT PF08146.12 CEP08664.1 - 6.3e-41 139.8 0.7 6.3e-41 139.8 0.7 3.1 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CEP08664.1 - 7.4e-17 61.8 3.8 7.4e-17 61.8 3.8 6.1 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 CEP08664.1 - 0.0043 17.5 1.4 26 5.5 0.0 5.6 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 CEP08664.1 - 0.09 13.1 4.0 21 5.7 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat ING PF12998.7 CEP08664.1 - 2.8 8.6 5.3 1.2 9.8 0.1 3.3 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Ribosomal_S13_N PF08069.12 CEP08665.1 - 1.7e-29 101.6 0.1 3.8e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CEP08665.1 - 6.2e-14 52.0 0.6 8.4e-14 51.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 zf-A20 PF01754.16 CEP08666.1 - 1e-09 38.1 9.1 1e-09 38.1 9.1 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 CEP08666.1 - 2.2e-07 30.9 7.5 2.2e-07 30.9 7.5 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger SMN PF06003.12 CEP08666.1 - 0.027 13.7 9.1 0.024 13.9 8.3 1.3 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Tweety PF04906.13 CEP08666.1 - 0.074 11.7 0.4 0.098 11.3 0.4 1.1 1 0 0 1 1 1 0 Tweety UPF0547 PF10571.9 CEP08666.1 - 0.079 13.1 2.1 0.079 13.1 2.1 2.2 2 1 0 2 2 1 0 Uncharacterised protein family UPF0547 Ndc1_Nup PF09531.10 CEP08666.1 - 0.23 10.1 11.5 0.27 9.9 11.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 CEP08666.1 - 0.35 10.8 9.5 0.45 10.4 9.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 CEP08666.1 - 0.6 8.9 7.0 0.73 8.6 7.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain KAR9 PF08580.10 CEP08666.1 - 0.72 8.3 18.3 0.81 8.1 18.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.9 CEP08666.1 - 2.4 6.6 14.8 2.8 6.4 14.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 CEP08666.1 - 5.2 8.1 4.8 3.3 8.7 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Alpha_GJ PF03229.13 CEP08666.1 - 5.6 7.5 23.9 8.2 7.0 11.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4711 PF15829.5 CEP08666.1 - 7.5 6.4 10.3 0.28 11.1 4.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) SPX PF03105.19 CEP08666.1 - 7.6 6.3 14.0 9.6 6.0 14.0 1.2 1 0 0 1 1 1 0 SPX domain Pex14_N PF04695.13 CEP08667.1 - 3e-07 31.2 10.6 3.5e-07 31.0 10.6 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SMN PF06003.12 CEP08667.1 - 7.9e-06 25.3 5.3 7.9e-06 25.3 5.3 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) PMSI1 PF15322.6 CEP08667.1 - 0.016 14.6 2.1 0.024 14.1 2.1 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative BUD22 PF09073.10 CEP08667.1 - 0.084 12.2 9.1 0.1 11.9 9.1 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CEP08667.1 - 0.38 9.0 10.5 0.38 9.0 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CEP08667.1 - 0.56 8.4 13.8 0.57 8.3 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 CEP08667.1 - 1.3 9.1 6.1 1.5 9.0 6.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4589 PF15252.6 CEP08667.1 - 1.8 8.6 7.1 2.1 8.3 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) DUF4449 PF14613.6 CEP08667.1 - 3.5 7.7 8.8 4.1 7.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Rrn6 PF10214.9 CEP08667.1 - 4.4 5.7 6.6 5.1 5.5 6.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Merozoite_SPAM PF07133.11 CEP08667.1 - 7.2 6.6 28.4 8.8 6.3 28.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 CEP08667.1 - 10 5.5 16.1 11 5.3 16.1 1.0 1 0 0 1 1 1 0 SDA1 FYVE PF01363.21 CEP08668.1 - 8.6e-22 77.1 26.4 1e-16 60.8 8.3 2.5 2 0 0 2 2 2 2 FYVE zinc finger Rbsn PF11464.8 CEP08668.1 - 8.7e-13 47.8 0.0 2.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 CEP08668.1 - 0.0023 18.1 4.0 0.0023 18.1 4.0 4.0 3 1 1 4 4 4 1 AN1-like Zinc finger zinc_ribbon_9 PF14369.6 CEP08668.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon Pyridoxal_deC PF00282.19 CEP08669.1 - 3.4e-18 65.5 0.0 5.2e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CEP08669.1 - 3.7e-09 36.0 0.0 7e-09 35.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEP08669.1 - 1.7e-06 27.6 0.1 2.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 CEP08670.1 - 4.1e-25 87.6 5.3 4.1e-06 27.4 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Ribosomal_L21p PF00829.21 CEP08670.1 - 4.3e-25 87.9 4.4 1.1e-24 86.5 4.4 1.8 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ANAPC4_WD40 PF12894.7 CEP08670.1 - 1.2e-16 60.8 1.9 0.019 15.2 0.0 6.5 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CEP08670.1 - 1.5e-09 37.3 0.0 3.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CEP08670.1 - 4.6e-09 35.7 6.9 0.00093 18.2 0.2 4.4 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 CEP08670.1 - 4e-05 23.4 0.0 9.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 CEP08670.1 - 6.2e-05 21.8 1.3 0.0083 14.8 0.6 3.0 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CEP08670.1 - 0.0014 17.7 0.6 0.094 11.6 0.0 3.1 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 CEP08670.1 - 0.03 13.9 0.0 0.28 10.7 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain WD40_like PF17005.5 CEP08670.1 - 0.031 13.6 10.3 0.44 9.8 1.7 3.7 3 1 1 4 4 4 0 WD40-like domain AMP-binding PF00501.28 CEP08671.1 - 1.1e-97 327.4 0.1 1.4e-97 327.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP08671.1 - 1.1e-24 87.1 0.1 2.7e-24 85.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEP08671.1 - 1.4e-16 60.1 3.6 4.9e-16 58.4 0.7 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 CEP08672.1 - 5e-59 194.9 13.5 8.5e-09 35.9 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CEP08672.1 - 9.7e-27 93.1 14.9 1.4e-26 92.6 14.9 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CEP08672.1 - 3.3e-20 72.2 0.0 0.0013 19.0 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP08672.1 - 1.8e-08 34.1 0.0 0.019 14.3 0.0 4.2 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CEP08672.1 - 1.6e-06 27.3 0.1 0.63 8.9 0.0 5.1 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP08672.1 - 1.6e-05 23.8 0.5 0.23 10.0 0.0 4.5 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 CEP08672.1 - 0.00049 20.0 1.0 0.9 9.6 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CEP08672.1 - 0.0046 16.3 0.1 1.5 8.1 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CEP08672.1 - 0.0066 15.0 0.7 0.42 9.1 0.2 2.3 1 1 1 2 2 2 1 Cytochrome D1 heme domain CEP63 PF17045.5 CEP08672.1 - 0.019 14.9 6.1 0.031 14.2 6.1 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF5122 PF17164.4 CEP08672.1 - 0.097 13.0 3.7 50 4.3 0.0 5.1 6 0 0 6 6 5 0 Domain of unknown function (DUF5122) beta-propeller Exonuc_VII_L PF02601.15 CEP08672.1 - 0.1 12.1 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMS1_N PF10433.9 CEP08672.1 - 0.11 11.1 0.0 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term APG6_N PF17675.1 CEP08672.1 - 0.12 12.9 8.5 0.18 12.3 8.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_S9_N PF02897.15 CEP08672.1 - 0.16 10.7 0.0 1.2 7.9 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF724 PF05266.14 CEP08672.1 - 0.18 11.6 4.2 0.26 11.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 CEP08672.1 - 0.28 10.0 7.3 0.41 9.5 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CEP08672.1 - 0.48 9.8 8.9 0.71 9.3 8.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 CREPT PF16566.5 CEP08672.1 - 0.78 9.9 4.9 1.3 9.2 4.9 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TPX2 PF06886.11 CEP08672.1 - 4 7.7 7.6 7.2 6.9 7.6 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Phage_Mu_Gam PF07352.12 CEP08672.1 - 6.5 6.6 8.1 5.7 6.8 3.4 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein FAD_binding_1 PF00667.20 CEP08673.1 - 2e-40 138.7 0.0 3.3e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP08673.1 - 4.2e-32 111.3 0.0 7.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CEP08673.1 - 1.4e-16 61.1 0.0 3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 CEP08673.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Glyco_trans_A_1 PF09318.10 CEP08673.1 - 0.071 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A Flavodoxin_5 PF12724.7 CEP08673.1 - 0.074 13.3 0.0 0.69 10.2 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain HTH_23 PF13384.6 CEP08674.1 - 5.3e-05 22.9 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 CEP08674.1 - 0.00014 21.7 0.1 0.00066 19.4 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP08674.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.18 CEP08674.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 'Paired box' domain FlgM PF04316.13 CEP08675.1 - 0.023 15.1 0.0 0.08 13.3 0.2 1.8 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Ras PF00071.22 CEP08676.1 - 6.1e-65 217.8 0.6 7.3e-65 217.5 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08676.1 - 2.3e-36 124.7 0.1 2.3e-36 124.7 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08676.1 - 4.5e-17 62.0 0.2 5.5e-17 61.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP08676.1 - 1.3e-06 28.1 0.8 2.7e-06 27.0 0.8 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP08676.1 - 1.6e-05 24.4 0.1 2.4e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP08676.1 - 2.2e-05 24.5 0.0 5.4e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP08676.1 - 2.8e-05 24.1 0.3 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEP08676.1 - 6e-05 22.6 0.0 9.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CEP08676.1 - 0.0086 15.9 0.4 0.019 14.7 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CEP08676.1 - 0.0099 16.3 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 CEP08676.1 - 0.014 14.7 0.2 0.17 11.1 0.0 2.2 2 1 0 2 2 2 0 Septin AAA_25 PF13481.6 CEP08676.1 - 0.02 14.5 0.3 0.48 10.0 0.3 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP08676.1 - 0.033 14.7 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CEP08676.1 - 0.044 13.3 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 CEP08676.1 - 0.048 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CEP08676.1 - 0.05 13.9 0.0 0.065 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhyH PF05721.13 CEP08676.1 - 0.065 13.5 0.1 0.084 13.1 0.1 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) AAA_5 PF07728.14 CEP08676.1 - 0.069 13.2 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CEP08676.1 - 0.11 12.9 0.1 0.59 10.6 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) HTH_psq PF05225.16 CEP08678.1 - 0.00056 19.6 0.1 0.0057 16.4 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 CEP08678.1 - 0.00084 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 CEP08678.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 CEP08678.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 CEP08678.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.19 CEP08678.1 - 0.032 14.0 0.5 0.078 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family CENP-B_N PF04218.13 CEP08678.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_17 PF12728.7 CEP08678.1 - 0.043 14.0 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 CEP08678.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 CEP08678.1 - 0.078 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 CEP08678.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain RVT_1 PF00078.27 CEP08679.1 - 9.1e-35 120.2 0.0 1.6e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP08679.1 - 4.1e-07 30.6 0.8 1.3e-06 29.1 0.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP08679.1 - 0.0058 16.2 0.1 0.017 14.6 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP08679.1 - 0.012 15.5 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP08679.1 - 0.016 15.3 1.2 0.016 15.3 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF5012 PF16404.5 CEP08680.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Peptidase_M50 PF02163.22 CEP08682.1 - 1.2e-09 37.8 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M50 Band_7_1 PF13421.6 CEP08682.1 - 0.035 13.8 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family MFS_MOT1 PF16983.5 CEP08682.1 - 0.74 10.2 4.7 9.5 6.7 0.3 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily ER_lumen_recept PF00810.18 CEP08683.1 - 8.3e-35 120.8 3.4 8.3e-35 120.8 3.4 1.3 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CEP08683.1 - 0.039 13.7 1.2 0.076 12.8 0.2 2.0 2 0 0 2 2 2 0 PQ loop repeat Chromo PF00385.24 CEP08686.1 - 2.5e-10 40.1 1.6 5.2e-10 39.1 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP08686.1 - 0.00053 19.8 0.6 0.0037 17.1 0.2 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tissue_fac PF01108.17 CEP08686.1 - 0.041 13.7 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Tissue factor Asp_protease_2 PF13650.6 CEP08688.1 - 2.4e-07 31.3 0.1 5.8e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CEP08688.1 - 5.3e-07 29.4 10.3 1.3e-05 25.0 1.1 2.4 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.6 CEP08688.1 - 1.8e-05 25.2 0.1 5.1e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 CEP08688.1 - 0.01 15.8 8.8 0.05 13.6 1.8 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP08689.1 - 0.00017 21.5 1.7 0.00034 20.6 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEP08689.1 - 0.00061 19.5 0.5 0.0014 18.3 0.5 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger Retrotrans_gag PF03732.17 CEP08689.1 - 0.006 16.8 0.3 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-C2H2_2 PF12756.7 CEP08689.1 - 0.087 13.2 0.6 0.39 11.1 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RT_RNaseH_2 PF17919.1 CEP08690.1 - 7.5e-32 109.3 0.1 1.8e-31 108.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08690.1 - 8.6e-30 103.1 0.5 1.7e-29 102.1 0.5 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08690.1 - 8.9e-24 84.2 0.0 1.9e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP08690.1 - 3.2e-05 24.5 0.0 0.00056 20.5 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP08690.1 - 4.3e-05 24.0 0.0 0.00031 21.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CEP08690.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease WD40 PF00400.32 CEP08691.1 - 4e-13 49.6 2.6 6e-06 26.9 0.7 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 CEP08691.1 - 0.013 14.2 0.2 0.016 13.9 0.2 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CEP08691.1 - 0.11 12.6 0.0 0.63 10.1 0.0 1.9 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region bZIP_2 PF07716.15 CEP08692.1 - 8.5e-11 41.8 10.6 8.5e-11 41.8 10.6 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP08692.1 - 0.0078 16.3 8.4 0.0078 16.3 8.4 2.6 2 0 0 2 2 2 1 bZIP transcription factor PspB PF06667.12 CEP08692.1 - 0.068 13.2 2.3 0.25 11.4 2.3 2.0 1 0 0 1 1 1 0 Phage shock protein B IFP_35_N PF07334.13 CEP08692.1 - 0.087 12.9 7.1 0.05 13.7 2.1 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus XhlA PF10779.9 CEP08692.1 - 0.57 10.4 8.2 0.066 13.4 2.0 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF1319 PF07028.11 CEP08692.1 - 3.4 7.9 8.3 0.92 9.8 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) MCM PF00493.23 CEP08693.1 - 4.5e-102 339.9 0.0 7e-102 339.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEP08693.1 - 7.8e-31 106.5 0.2 1.3e-30 105.8 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEP08693.1 - 1.7e-20 73.3 1.2 4.2e-20 72.0 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEP08693.1 - 1.7e-15 57.4 0.4 3.8e-15 56.3 0.4 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEP08693.1 - 2.2e-07 30.5 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEP08693.1 - 2.1e-06 27.8 0.1 8.7e-06 25.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CEP08693.1 - 0.0068 16.2 0.6 0.022 14.6 0.6 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 CEP08693.1 - 0.024 14.5 0.0 0.09 12.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEP08693.1 - 0.13 11.9 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 CEP08693.1 - 0.19 12.1 0.6 11 6.4 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain Fer2 PF00111.27 CEP08694.1 - 6.7e-08 32.4 1.3 8.3e-08 32.1 1.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ureide_permease PF07168.11 CEP08695.1 - 0.76 8.5 6.5 0.72 8.5 4.3 1.8 1 1 1 2 2 2 0 Ureide permease PEHE PF15275.6 CEP08695.1 - 6.9 7.3 13.8 0.16 12.6 5.9 2.2 2 0 0 2 2 2 0 PEHE domain AAA_2 PF07724.14 CEP08696.1 - 2.8e-54 183.8 6.5 3.2e-51 173.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CEP08696.1 - 3.1e-34 117.0 1.2 3.1e-34 117.0 1.2 3.4 2 1 1 4 4 3 1 AAA lid domain AAA PF00004.29 CEP08696.1 - 2.2e-27 96.1 0.1 1.9e-14 54.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CEP08696.1 - 7.3e-24 83.6 0.1 7.3e-24 83.6 0.1 3.1 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CEP08696.1 - 2.9e-20 72.7 0.6 1.9e-11 44.2 0.0 4.0 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CEP08696.1 - 1.6e-15 57.0 0.0 3e-07 30.5 0.1 3.2 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CEP08696.1 - 1.3e-13 51.6 0.8 2.8e-07 31.1 0.1 4.6 3 2 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CEP08696.1 - 3.4e-10 39.9 0.1 2e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 CEP08696.1 - 1.6e-08 34.2 0.0 0.00018 21.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 CEP08696.1 - 1.8e-08 34.0 0.0 2.1e-05 24.0 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 CEP08696.1 - 4.4e-08 33.5 0.2 0.017 15.4 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CEP08696.1 - 6.7e-08 32.6 0.3 0.0084 16.1 0.0 3.8 4 1 0 4 4 2 2 AAA domain Mg_chelatase PF01078.21 CEP08696.1 - 1.3e-07 31.2 0.1 0.0059 16.0 0.1 3.5 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEP08696.1 - 3e-07 30.4 0.0 0.03 14.1 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 CEP08696.1 - 3.7e-05 23.0 0.6 0.27 10.3 0.1 3.5 2 2 0 2 2 2 2 Protein of unknown function (DUF815) Roc PF08477.13 CEP08696.1 - 8e-05 22.8 0.0 0.74 10.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CEP08696.1 - 0.00011 22.2 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CEP08696.1 - 0.00024 21.5 0.0 0.91 9.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase EzrA PF06160.12 CEP08696.1 - 0.00028 19.2 12.5 0.0005 18.4 12.5 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Torsin PF06309.11 CEP08696.1 - 0.00046 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 Torsin RuvB_N PF05496.12 CEP08696.1 - 0.00052 19.8 4.4 1 9.1 0.3 4.3 3 1 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CEP08696.1 - 0.00079 19.2 0.0 0.56 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CEP08696.1 - 0.00084 19.3 0.0 1 9.4 0.0 2.9 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CEP08696.1 - 0.0011 19.5 0.1 0.43 11.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 CEP08696.1 - 0.0011 19.5 8.2 0.16 12.5 0.0 4.3 4 2 0 4 4 3 2 AAA domain AAA_28 PF13521.6 CEP08696.1 - 0.0012 19.1 0.1 5.8 7.1 0.0 4.0 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CEP08696.1 - 0.0028 17.6 0.0 4.3 7.2 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase AAA_3 PF07726.11 CEP08696.1 - 0.0052 16.6 0.0 1.6 8.6 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CEP08696.1 - 0.0082 15.9 0.0 1.5 8.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP08696.1 - 0.0084 16.3 0.0 3.8 7.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain BLOC1_2 PF10046.9 CEP08696.1 - 0.01 16.1 4.5 0.01 16.1 4.5 2.5 2 1 1 3 3 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SRP54 PF00448.22 CEP08696.1 - 0.013 15.2 0.0 1.3 8.6 0.0 3.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 CEP08696.1 - 0.013 15.5 0.0 1.1 9.3 0.0 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 CEP08696.1 - 0.014 15.2 0.0 0.93 9.2 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 CEP08696.1 - 0.016 15.5 0.2 0.34 11.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CEP08696.1 - 0.017 15.0 0.1 4.8 7.1 0.0 3.4 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.9 CEP08696.1 - 0.027 14.2 0.0 1.4 8.7 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 CEP08696.1 - 0.044 13.7 14.2 1.1 9.1 0.1 5.1 3 2 2 6 6 5 0 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 CEP08696.1 - 0.068 12.9 0.2 8.9 6.1 0.0 3.2 4 0 0 4 4 3 0 DNA polymerase III, delta subunit AAA_25 PF13481.6 CEP08696.1 - 0.091 12.3 1.2 2 7.9 0.0 3.2 4 1 0 4 4 2 0 AAA domain Tup_N PF08581.10 CEP08696.1 - 0.92 9.8 9.6 0.047 14.0 2.3 2.8 3 0 0 3 3 1 0 Tup N-terminal DASH_Spc19 PF08287.11 CEP08696.1 - 7.4 6.5 12.6 12 5.8 9.1 2.5 2 1 0 2 2 2 0 Spc19 FlxA PF14282.6 CEP08696.1 - 8.7 6.4 8.1 16 5.6 2.3 2.5 1 1 1 2 2 2 0 FlxA-like protein UAA PF08449.11 CEP08697.1 - 1.2e-50 172.5 14.8 1.4e-50 172.3 14.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEP08697.1 - 2.2e-10 40.8 12.7 6.5e-08 32.8 5.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP08697.1 - 0.00081 18.7 6.0 0.15 11.2 0.0 3.1 1 1 2 3 3 3 2 Nucleotide-sugar transporter DUF4534 PF15049.6 CEP08697.1 - 0.0074 16.0 0.2 0.02 14.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) TPT PF03151.16 CEP08697.1 - 0.16 11.3 8.4 0.51 9.6 8.4 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family AAA PF00004.29 CEP08698.1 - 8.8e-54 181.5 0.1 1.6e-36 125.6 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP08698.1 - 8.1e-09 35.2 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 CEP08698.1 - 2.8e-06 27.6 0.0 0.00063 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CEP08698.1 - 5.2e-06 26.5 0.0 0.0086 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEP08698.1 - 5.1e-05 23.6 0.3 0.0044 17.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CEP08698.1 - 0.00013 21.7 0.0 0.00054 19.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEP08698.1 - 0.00049 20.5 0.3 0.031 14.7 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CEP08698.1 - 0.0012 18.9 0.0 0.081 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEP08698.1 - 0.0013 19.2 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEP08698.1 - 0.0033 17.2 0.1 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CEP08698.1 - 0.0045 16.5 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CEP08698.1 - 0.0048 16.2 0.4 0.045 12.9 0.2 2.4 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 CEP08698.1 - 0.0055 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEP08698.1 - 0.011 15.3 0.0 0.072 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP08698.1 - 0.013 15.2 0.3 0.074 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP08698.1 - 0.017 15.5 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 CEP08698.1 - 0.02 14.7 0.1 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 CEP08698.1 - 0.024 15.2 0.0 0.059 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 CEP08698.1 - 0.028 14.3 0.2 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CEP08698.1 - 0.033 13.9 0.0 0.45 10.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain IPT PF01745.16 CEP08698.1 - 0.043 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase TsaE PF02367.17 CEP08698.1 - 0.044 13.8 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CEP08698.1 - 0.046 12.8 0.1 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 CEP08698.1 - 0.063 12.7 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 CEP08698.1 - 0.092 12.6 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.6 CEP08698.1 - 0.092 13.2 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEP08698.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEP08698.1 - 0.12 12.3 0.3 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 CEP08698.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP08698.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 CEP08699.1 - 5.2e-19 68.3 5.6 9.4e-07 29.1 0.2 4.5 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP08699.1 - 8.5e-14 51.7 27.5 1.1e-05 26.0 0.8 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CEP08699.1 - 5.8e-08 32.1 0.5 1.5e-05 24.2 0.0 3.2 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEP08699.1 - 1.4e-05 25.0 1.2 0.023 14.6 0.1 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CEP08699.1 - 0.002 17.5 0.1 0.42 9.9 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Glyco_hyd_101C PF17451.2 CEP08699.1 - 0.047 14.0 2.2 3.9 7.8 0.6 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Gly_acyl_tr_N PF06021.11 CEP08699.1 - 0.36 10.9 2.3 0.32 11.1 0.5 1.7 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase IKI3 PF04762.12 CEP08699.1 - 2.9 5.8 7.0 0.71 7.8 1.2 2.2 1 1 1 3 3 3 0 IKI3 family NARP1 PF12569.8 CEP08700.1 - 3.6e-173 577.2 24.1 3.6e-173 577.2 24.1 2.2 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CEP08700.1 - 7.8e-13 47.5 27.7 8.3e-05 22.4 2.0 9.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEP08700.1 - 1.1e-12 47.6 14.1 0.33 11.9 0.0 10.3 9 3 4 13 13 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP08700.1 - 3.1e-10 40.4 28.0 0.088 13.3 1.3 8.8 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEP08700.1 - 6.9e-10 39.4 7.2 6 7.6 0.2 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP08700.1 - 5.8e-08 32.9 12.4 0.015 15.5 0.0 5.4 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEP08700.1 - 7.2e-08 32.0 4.2 0.0019 17.9 1.8 6.0 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 CEP08700.1 - 1.7e-07 31.3 0.1 0.066 13.4 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP08700.1 - 2.4e-07 30.4 25.4 0.0087 16.2 1.1 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CEP08700.1 - 4.3e-07 29.6 0.9 0.42 10.2 0.0 3.9 3 0 0 3 3 3 3 Bacterial type III secretion protein (HrpB1_HrpK) TPR_1 PF00515.28 CEP08700.1 - 5.2e-06 26.0 20.6 0.0086 15.9 3.3 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEP08700.1 - 8.4e-06 25.2 16.5 0.00038 19.8 0.4 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP08700.1 - 8.6e-06 25.8 10.1 0.56 10.7 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP08700.1 - 0.00035 20.4 0.7 0.62 10.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP08700.1 - 0.0012 19.0 17.3 0.45 10.8 0.0 6.8 7 1 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP08700.1 - 0.055 14.1 0.0 4 8.3 0.0 3.8 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP08700.1 - 0.068 13.8 15.5 2.7 8.8 0.0 7.5 10 1 0 10 10 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEP08700.1 - 4 7.4 8.7 22 5.1 0.2 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 CEP08701.1 - 4e-48 164.1 0.0 4.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP08701.1 - 6.8e-08 31.8 0.1 9.1e-08 31.4 0.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 CEP08701.1 - 0.0019 16.9 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 CEP08701.1 - 0.02 13.8 0.4 0.054 12.4 0.1 1.7 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.21 CEP08701.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Acyl-CoA_dh_1 PF00441.24 CEP08702.1 - 2.9e-32 111.9 0.8 4.3e-32 111.4 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEP08702.1 - 8.1e-21 74.0 0.0 2.1e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEP08702.1 - 2e-14 54.2 0.0 4.2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP08702.1 - 4.4e-13 49.7 1.1 7.6e-13 48.9 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CEP08702.1 - 0.00039 20.2 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal START PF01852.19 CEP08703.1 - 1.5e-24 86.6 0.5 2.8e-14 53.0 0.1 2.6 2 0 0 2 2 2 2 START domain Glyco_hydro_5_C PF18564.1 CEP08703.1 - 0.00012 22.5 0.1 0.0005 20.6 0.1 2.1 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Pkinase PF00069.25 CEP08704.1 - 4.3e-67 226.3 0.9 1.8e-66 224.2 0.0 2.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08704.1 - 1e-40 139.6 0.0 7.9e-40 136.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP08704.1 - 8.6e-05 22.0 0.1 0.00024 20.5 0.1 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP08704.1 - 0.00042 20.3 2.8 0.00088 19.3 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP08704.1 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.11 CEP08704.1 - 0.063 12.9 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 CEP08704.1 - 0.091 12.3 0.0 0.091 12.3 0.0 3.0 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL SNF2_N PF00176.23 CEP08705.1 - 6.1e-48 163.3 0.3 1e-46 159.3 0.3 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP08705.1 - 2.3e-17 63.3 0.1 9.8e-17 61.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP08705.1 - 1.9e-11 44.3 0.0 8.1e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP08705.1 - 4.8e-05 22.7 1.1 7.9e-05 22.0 1.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CEP08705.1 - 0.0003 20.5 0.0 0.00082 19.1 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 CEP08705.1 - 0.002 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NDT80_PhoG PF05224.12 CEP08706.1 - 1.8e-37 129.4 0.0 7e-37 127.5 0.0 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pkinase PF00069.25 CEP08707.1 - 1.3e-27 96.8 0.0 1.8e-26 93.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08707.1 - 2.1e-08 33.8 0.0 4.4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4524 PF15025.6 CEP08707.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) MFS_1 PF07690.16 CEP08708.1 - 3.4e-25 88.7 6.8 3.4e-25 88.7 6.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RhoGEF PF00621.20 CEP08709.1 - 9.2e-39 133.6 6.0 2.4e-38 132.2 6.0 1.8 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 CEP08709.1 - 6.6e-31 106.4 0.3 2.9e-30 104.3 0.1 2.3 3 0 0 3 3 3 1 CDC24 Calponin PH_10 PF15411.6 CEP08709.1 - 2.9e-19 69.5 1.7 6.1e-19 68.5 1.7 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 CEP08709.1 - 2.4e-12 46.6 0.3 6.2e-12 45.3 0.3 1.7 1 0 0 1 1 1 1 PB1 domain CH PF00307.31 CEP08709.1 - 0.00055 20.1 0.1 0.0023 18.1 0.1 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain PH PF00169.29 CEP08709.1 - 0.0052 17.3 1.9 0.0064 17.0 0.4 2.0 2 0 0 2 2 2 1 PH domain MAM PF00629.23 CEP08709.1 - 0.15 12.0 2.4 0.4 10.6 2.4 1.7 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu RNA_pol_3_Rpc31 PF11705.8 CEP08709.1 - 2.8 8.1 6.7 0.19 12.0 1.3 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 HSCB_C PF07743.13 CEP08710.1 - 3.5e-18 65.9 3.0 3.5e-18 65.9 3.0 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CEP08710.1 - 1.1e-05 25.5 0.7 2.8e-05 24.1 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain zf-tcix PF14952.6 CEP08710.1 - 0.086 12.5 1.6 0.16 11.6 1.6 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zinc_ribbon_2 PF13240.6 CEP08710.1 - 0.096 12.4 1.0 0.16 11.8 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain NDK PF00334.19 CEP08711.1 - 9.8e-45 151.9 0.0 3.3e-44 150.2 0.0 2.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AAA_30 PF13604.6 CEP08713.1 - 2.2e-14 53.6 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 CEP08713.1 - 4.1e-14 52.5 0.0 4.3e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_22 PF13401.6 CEP08713.1 - 1.5e-05 25.3 0.2 8e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP08713.1 - 4.4e-05 23.8 0.1 0.00011 22.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CEP08713.1 - 0.00026 20.9 0.1 0.0035 17.2 0.1 2.0 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CEP08713.1 - 0.0003 20.6 0.0 0.00055 19.7 0.0 1.4 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CEP08713.1 - 0.0022 18.4 0.0 0.0032 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CEP08713.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain TK PF00265.18 CEP08713.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.0 1 0 0 1 1 1 0 Thymidine kinase DUF2075 PF09848.9 CEP08713.1 - 0.033 13.4 0.4 0.2 10.9 0.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 CEP08713.1 - 0.036 13.3 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 CEP08713.1 - 0.057 13.8 0.0 0.096 13.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2791 PF10923.8 CEP08713.1 - 0.059 12.2 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 CEP08713.1 - 0.087 13.2 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CEP08713.1 - 0.099 13.2 0.2 0.17 12.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter DUF87 PF01935.17 CEP08713.1 - 0.11 12.5 0.1 0.12 12.5 0.1 1.2 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 CEP08713.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Retrotrans_gag PF03732.17 CEP08715.1 - 3.6e-05 23.9 0.3 0.00021 21.5 0.0 2.3 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP08715.1 - 0.0037 17.9 0.0 0.0081 16.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RNF220 PF15926.5 CEP08715.1 - 0.031 13.9 2.5 0.056 13.1 2.5 1.4 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 gag-asp_proteas PF13975.6 CEP08715.1 - 0.034 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4939 PF16297.5 CEP08715.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RP-C_C PF11800.8 CEP08715.1 - 0.14 12.2 2.9 2 8.4 2.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region RT_RNaseH PF17917.1 CEP08716.1 - 1.1e-35 122.1 0.0 2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP08716.1 - 2.5e-32 110.9 0.0 4.8e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08716.1 - 1e-22 80.7 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP08716.1 - 0.00028 21.5 0.0 0.00097 19.7 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP08716.1 - 0.00071 20.1 0.0 0.0025 18.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CEP08717.1 - 8.8e-05 22.4 15.0 0.0025 17.8 1.6 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CEP08717.1 - 0.00085 19.2 0.6 0.00085 19.2 0.6 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEP08717.1 - 0.054 13.2 0.9 0.054 13.2 0.9 2.8 2 1 1 3 3 3 0 Zinc knuckle DUF1340 PF07067.11 CEP08717.1 - 0.092 12.1 0.7 0.16 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) zf-CCHC_6 PF15288.6 CEP08717.1 - 1.1 9.2 9.1 1.1 9.2 0.8 2.9 3 0 0 3 3 3 0 Zinc knuckle DUF1840 PF08895.11 CEP08717.1 - 3.7 7.9 6.1 1.9 8.8 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1840) zf-CCHC PF00098.23 CEP08718.1 - 1.3e-06 28.2 19.3 3.8e-05 23.6 5.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP08718.1 - 0.85 9.4 21.5 2.8 7.7 6.5 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger IMUP PF15761.5 CEP08718.1 - 0.88 10.3 14.7 3.2 8.5 7.0 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein Exo_endo_phos PF03372.23 CEP08719.1 - 0.0025 17.3 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FH2 PF02181.23 CEP08720.1 - 8.2e-69 232.5 13.1 1.5e-68 231.6 13.1 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CEP08720.1 - 1.1e-29 103.4 1.0 1.2e-28 100.0 0.0 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEP08720.1 - 1.5e-26 93.2 1.5 1.2e-25 90.3 0.3 2.8 2 0 0 2 2 2 1 Diaphanous FH3 Domain GATase PF00117.28 CEP08721.1 - 9.7e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 CEP08721.1 - 2.1e-05 23.6 0.0 3.6e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Homoserine O-succinyltransferase Peptidase_C26 PF07722.13 CEP08721.1 - 6.7e-05 22.7 2.0 0.0004 20.2 2.0 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CEP08721.1 - 8.1e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CEP08721.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain R-HINP1I PF11463.8 CEP08721.1 - 0.049 13.1 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease PPTA PF01239.22 CEP08722.1 - 1e-40 136.3 17.9 5.8e-08 32.2 2.6 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 CEP08722.1 - 0.00018 21.6 0.6 0.84 10.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat tRNA-synt_2b PF00587.25 CEP08723.1 - 6.4e-19 68.6 0.0 1.5e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEP08723.1 - 1.2e-05 25.3 0.1 3.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain RT_RNaseH_2 PF17919.1 CEP08724.1 - 4.2e-30 103.7 0.0 5.5e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08724.1 - 1.5e-26 92.7 0.1 2e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UvrD_C_2 PF13538.6 CEP08725.1 - 4.6e-05 23.2 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MULE PF10551.9 CEP08726.1 - 0.0003 21.2 0.4 0.00087 19.7 0.1 2.0 2 0 0 2 2 2 1 MULE transposase domain ERp29 PF07749.12 CEP08727.1 - 0.052 14.5 0.0 0.11 13.5 0.0 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain RT_RNaseH PF17917.1 CEP08728.1 - 3.9e-30 104.2 0.0 8.7e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP08728.1 - 1.5e-29 102.0 0.0 3.8e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08728.1 - 4.5e-22 78.7 0.1 1.1e-21 77.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP08728.1 - 6.9e-10 39.4 0.1 2.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CEP08728.1 - 3e-08 33.5 0.0 7.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 CEP08728.1 - 3.1e-08 34.2 0.1 1.1e-07 32.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CEP08728.1 - 0.00045 20.0 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 CEP08728.1 - 0.066 12.8 1.7 0.073 12.6 0.3 1.7 2 0 0 2 2 2 0 Ty3 transposon peptidase CHASE9 PF17153.4 CEP08729.1 - 0.1 12.8 0.0 0.45 10.7 0.0 1.9 1 1 1 2 2 2 0 Periplasmic sensor domain, extracellular KDZ PF18758.1 CEP08730.1 - 5.6e-32 111.1 1.4 9.4e-32 110.4 1.4 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DDE_3 PF13358.6 CEP08731.1 - 1e-23 83.7 0.0 5.6e-22 78.1 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP08731.1 - 0.0048 17.0 0.4 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 CEP08731.1 - 0.0085 16.3 0.4 3.4 7.9 0.0 3.4 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP08731.1 - 0.0095 15.9 0.1 0.077 13.0 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn helix Retrotrans_gag PF03732.17 CEP08732.1 - 0.00031 20.9 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Atypical_Card PF18461.1 CEP08732.1 - 0.061 13.5 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Atypical caspase recruitment domain Helitron_like_N PF14214.6 CEP08734.1 - 7.9e-17 62.1 0.1 4.7e-09 36.7 0.0 2.5 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus RVP_2 PF08284.11 CEP08736.1 - 1.2e-10 41.3 0.1 3.4e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP08736.1 - 0.002 18.7 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP08736.1 - 0.0022 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease dDENN PF03455.19 CEP08736.1 - 0.0099 15.9 0.7 0.025 14.6 0.7 1.6 1 0 0 1 1 1 1 dDENN domain zf-C2H2_10 PF16588.5 CEP08737.1 - 0.011 15.4 4.1 0.011 15.4 4.1 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 CEP08737.1 - 0.028 14.5 15.6 0.089 12.9 1.4 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEP08737.1 - 0.88 9.5 17.7 0.81 9.6 7.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP08737.1 - 8.9 6.1 9.3 2.7 7.8 0.7 2.5 3 0 0 3 3 3 0 Zinc knuckle Helitron_like_N PF14214.6 CEP08738.1 - 1.1e-10 42.1 0.2 3.1e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus ABC_tran_CTD PF16326.5 CEP08739.1 - 0.15 12.3 0.2 0.24 11.7 0.2 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Fcf2 PF08698.11 CEP08740.1 - 0.013 15.8 0.5 0.02 15.2 0.5 1.3 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing Rotamase_3 PF13616.6 CEP08740.1 - 0.049 14.2 0.3 0.1 13.2 0.3 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain OST3_OST6 PF04756.13 CEP08740.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF5017 PF16409.5 CEP08742.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) MULE PF10551.9 CEP08743.1 - 8.6e-09 35.7 0.3 6.1e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 MULE transposase domain DUF2605 PF10792.9 CEP08743.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) PH PF00169.29 CEP08744.1 - 0.00033 21.1 0.1 0.00082 19.9 0.1 1.7 1 0 0 1 1 1 1 PH domain MMM1 PF10296.9 CEP08744.1 - 0.0067 15.5 0.0 0.0067 15.5 0.0 3.5 4 1 1 5 5 5 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 CEP08744.1 - 0.032 14.6 0.3 0.032 14.6 0.3 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3974 PF13120.6 CEP08744.1 - 0.065 13.3 0.1 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) HATPase_c PF02518.26 CEP08745.1 - 1.7e-31 109.0 0.2 4.3e-31 107.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP08745.1 - 1.2e-19 70.5 0.1 8.4e-19 67.8 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 CEP08745.1 - 1.1e-16 61.7 0.1 4.9e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 CEP08745.1 - 7.1e-16 58.0 0.0 2.5e-15 56.3 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CEP08745.1 - 6.6e-10 39.4 0.0 1.7e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 CEP08745.1 - 1.7e-09 37.5 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 CEP08745.1 - 4.8e-08 33.7 0.0 1.4e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 CEP08745.1 - 0.00026 20.3 0.0 0.00069 18.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Pkinase_Tyr PF07714.17 CEP08745.1 - 0.00053 19.3 0.0 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt PF00231.19 CEP08745.1 - 0.0067 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase ABC_tran PF00005.27 CEP08745.1 - 0.012 16.1 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CEP08745.1 - 0.025 14.3 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP08745.1 - 0.12 12.3 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 CEP08745.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PTB PF08416.13 CEP08745.1 - 0.23 11.6 0.8 23 5.2 0.0 3.4 3 0 0 3 3 3 0 Phosphotyrosine-binding domain tRNA-synt_2 PF00152.20 CEP08746.1 - 5.1e-104 347.7 0.1 6.2e-104 347.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CEP08746.1 - 8.2e-06 25.5 0.9 4.1e-05 23.2 0.1 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CEP08746.1 - 8.7e-06 25.6 0.0 4.4e-05 23.4 0.0 2.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain GAD PF02938.14 CEP08746.1 - 0.0036 17.5 0.0 0.042 14.1 0.0 2.5 2 1 0 2 2 2 1 GAD domain tRNA-synt_2b PF00587.25 CEP08746.1 - 0.03 14.3 0.1 0.06 13.3 0.1 1.7 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Integrase_H2C2 PF17921.1 CEP08747.1 - 1.5e-17 63.5 1.0 1.9e-16 59.9 0.5 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CEP08747.1 - 2.9e-16 59.7 0.0 6.1e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP08747.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Dev_Cell_Death PF10539.9 CEP08747.1 - 0.49 10.3 2.9 0.35 10.7 0.7 1.8 2 0 0 2 2 2 0 Development and cell death domain Bul1_N PF04425.12 CEP08748.1 - 0.0042 15.9 0.7 0.0043 15.9 0.7 1.0 1 0 0 1 1 1 1 Bul1 N terminus UCH_C PF18031.1 CEP08749.1 - 0.2 11.6 1.4 0.35 10.8 1.4 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Ribosomal_S19 PF00203.21 CEP08751.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S19 Bactofilin PF04519.13 CEP08752.1 - 0.016 15.5 0.1 0.38 11.1 0.1 2.1 2 0 0 2 2 2 0 Polymer-forming cytoskeletal DUF3575 PF12099.8 CEP08752.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) GSH_synthase PF03199.15 CEP08753.1 - 0.077 13.5 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 Eukaryotic glutathione synthase DUF1340 PF07067.11 CEP08753.1 - 0.11 11.8 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Osmo_CC PF08946.10 CEP08753.1 - 0.23 11.7 7.8 1.1 9.5 2.2 3.0 1 1 1 2 2 2 0 Osmosensory transporter coiled coil MFAP1 PF06991.11 CEP08753.1 - 0.32 10.8 3.3 0.36 10.6 2.8 1.4 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing RT_RNaseH_2 PF17919.1 CEP08754.1 - 3.4e-11 43.1 0.0 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_int_SAM_4 PF13495.6 CEP08756.1 - 0.027 14.9 2.4 4.8 7.7 0.2 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain SecA_SW PF07516.13 CEP08757.1 - 0.031 14.3 0.1 0.06 13.4 0.1 1.5 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Raptor_N PF14538.6 CEP08758.1 - 1.1e-65 220.1 0.0 2.8e-65 218.8 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CEP08758.1 - 4.4e-07 29.6 7.3 0.0052 16.9 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat WD40 PF00400.32 CEP08758.1 - 7.7e-07 29.7 9.8 0.11 13.4 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 CEP08758.1 - 2.9e-06 27.6 0.4 0.00031 21.1 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CEP08758.1 - 6.3e-06 26.3 0.0 0.00051 20.1 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 SUIM_assoc PF16619.5 CEP08758.1 - 0.00032 20.7 2.0 0.0016 18.5 2.0 2.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4441 PF14536.6 CEP08758.1 - 0.036 14.3 4.0 0.11 12.6 4.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) BBS2_Mid PF14783.6 CEP08758.1 - 0.055 13.5 0.1 15 5.7 0.0 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region HEAT_EZ PF13513.6 CEP08758.1 - 0.11 13.0 1.3 4.7 7.8 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat Pex14_N PF04695.13 CEP08758.1 - 5.5 7.6 13.6 17 6.1 4.3 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4154 PF13689.6 CEP08759.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 YfiR/HmsC-like RVT_1 PF00078.27 CEP08760.1 - 7.9e-09 35.4 0.0 9.2e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIG-L PF02585.17 CEP08761.1 - 0.053 14.2 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase DDE_Tnp_4 PF13359.6 CEP08762.1 - 0.004 16.8 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 CEP08762.1 - 0.024 14.3 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease RVT_1 PF00078.27 CEP08763.1 - 6.4e-22 78.2 0.0 1e-21 77.5 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CEP08767.1 - 4.5e-05 23.2 0.3 7e-05 22.6 0.3 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease PI3K_rbd PF00794.18 CEP08767.1 - 0.021 15.0 0.4 0.029 14.5 0.4 1.3 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Retrotrans_gag PF03732.17 CEP08768.1 - 0.00024 21.3 0.0 0.00086 19.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein WHEP-TRS PF00458.20 CEP08768.1 - 0.024 14.8 0.4 0.14 12.3 0.1 2.2 2 0 0 2 2 2 0 WHEP-TRS domain zf-RVT PF13966.6 CEP08769.1 - 0.002 18.8 0.1 0.0044 17.7 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP08770.1 - 1.1e-21 77.4 0.5 2.2e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.20 CEP08772.1 - 0.0025 17.6 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease rve PF00665.26 CEP08776.1 - 5e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CEP08776.1 - 0.033 14.5 0.0 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08777.1 - 1.5e-08 34.4 0.3 6.2e-07 29.1 0.0 2.9 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP08779.1 - 1.6e-11 44.1 1.2 2.8e-11 43.3 1.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP08779.1 - 0.00048 20.3 2.9 0.001 19.3 2.9 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 CEP08779.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP08781.1 - 2.5e-07 30.4 0.0 2.6e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CEP08782.1 - 1.7e-07 31.2 0.4 2.8e-07 30.5 0.4 1.3 1 0 0 1 1 1 1 Phage integrase family TA0956 PF11513.8 CEP08782.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 WRKY PF03106.15 CEP08783.1 - 0.026 14.7 0.9 0.065 13.5 0.9 1.7 1 0 0 1 1 1 0 WRKY DNA -binding domain DUF1857 PF08982.11 CEP08783.1 - 0.11 12.3 0.1 0.96 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) Aldedh PF00171.22 CEP08785.1 - 2.7e-163 543.8 0.0 3.1e-163 543.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP08785.1 - 5.9e-05 22.6 0.1 0.27 10.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 CEP08785.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glycos_transf_4 PF00953.21 CEP08786.1 - 2.7e-31 108.7 14.3 2.7e-31 108.7 14.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 4 Dpy-30 PF05186.13 CEP08786.1 - 1.4e-14 53.5 0.0 2.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif PP2C PF00481.21 CEP08787.1 - 5.5e-65 219.6 0.1 7.6e-65 219.1 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEP08787.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Hypoth_Ymh PF09509.10 CEP08787.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) mRNA_triPase PF02940.15 CEP08788.1 - 3.4e-54 183.9 4.9 4.5e-54 183.5 4.9 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain LIFR_D2 PF17971.1 CEP08788.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor D2 domain YwpF PF14183.6 CEP08788.1 - 0.088 12.8 0.2 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 YwpF-like protein Ras PF00071.22 CEP08789.1 - 1.3e-53 181.0 0.0 1.7e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08789.1 - 2.5e-21 76.1 0.0 4.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08789.1 - 8.2e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Aldedh PF00171.22 CEP08789.1 - 2.9e-07 29.4 0.0 4.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SRPRB PF09439.10 CEP08789.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ank_5 PF13857.6 CEP08790.1 - 8.4e-06 26.0 0.0 3.4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEP08790.1 - 0.003 17.9 0.0 0.033 14.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF4094 PF13334.6 CEP08790.1 - 0.062 13.7 0.6 0.68 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DEAD PF00270.29 CEP08791.1 - 2.8e-50 170.5 0.0 4.7e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP08791.1 - 9.4e-32 109.7 0.0 9.1e-31 106.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP08791.1 - 1.4e-05 25.1 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP08791.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CEP08791.1 - 0.18 12.1 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain eIF2_C PF09173.11 CEP08792.1 - 9.8e-34 115.5 1.3 1.7e-33 114.7 0.4 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CEP08792.1 - 2e-23 82.9 1.1 1.4e-22 80.2 1.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEP08792.1 - 2.1e-08 34.5 1.9 2.1e-08 34.5 1.9 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CEP08792.1 - 0.0012 18.8 0.9 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP08792.1 - 0.0019 18.2 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CEP08792.1 - 0.0082 16.1 0.2 0.021 14.8 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CEP08792.1 - 0.062 13.3 0.2 0.17 11.9 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Ribophorin_I PF04597.14 CEP08793.1 - 2.2e-136 455.6 8.1 2.6e-136 455.4 8.1 1.0 1 0 0 1 1 1 1 Ribophorin I DIOX_N PF14226.6 CEP08794.1 - 6.6e-35 120.4 0.1 3.7e-34 118.0 0.1 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEP08794.1 - 2.9e-17 63.0 0.0 5.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC2_membrane PF01061.24 CEP08795.1 - 1.2e-84 283.0 50.5 7.1e-47 159.5 18.6 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEP08795.1 - 2.3e-36 125.3 0.0 4.8e-20 72.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEP08795.1 - 6.7e-33 112.5 7.0 3.3e-25 87.8 0.3 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP08795.1 - 1.8e-14 54.1 0.1 4.6e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CEP08795.1 - 3.1e-05 24.4 0.0 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CEP08795.1 - 4.8e-05 23.3 0.0 0.15 11.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEP08795.1 - 0.00028 20.8 0.6 0.0037 17.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CEP08795.1 - 0.0022 18.2 0.2 0.46 10.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 CEP08795.1 - 0.0031 16.7 65.8 0.0041 16.3 17.5 4.1 2 2 0 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.6 CEP08795.1 - 0.0054 17.0 0.0 0.7 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEP08795.1 - 0.0066 16.0 0.2 0.036 13.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP08795.1 - 0.01 16.4 0.0 0.56 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEP08795.1 - 0.022 14.4 0.3 0.99 9.0 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CEP08795.1 - 0.024 14.4 0.7 0.024 14.4 0.7 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CEP08795.1 - 0.045 13.5 1.0 2.4 7.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CEP08795.1 - 0.048 13.8 0.5 11 6.1 0.2 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CEP08795.1 - 0.05 13.3 0.3 8.2 6.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CEP08795.1 - 0.18 12.2 0.4 23 5.4 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATG19_autophagy PF12744.7 CEP08795.1 - 0.29 10.3 0.7 0.98 8.6 0.7 1.8 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding AAA_23 PF13476.6 CEP08795.1 - 3.5 8.1 5.5 0.41 11.1 0.1 2.1 3 0 0 3 3 2 0 AAA domain UcrQ PF02939.16 CEP08796.1 - 7e-33 112.4 0.5 7.9e-33 112.2 0.5 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CEP08796.1 - 0.037 14.4 0.0 0.045 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Phage_holin_8 PF16931.5 CEP08796.1 - 0.046 13.7 0.7 0.055 13.4 0.7 1.1 1 0 0 1 1 1 0 Putative phage holin zf-RING_4 PF14570.6 CEP08797.1 - 6.8e-23 80.2 12.2 1.4e-22 79.2 12.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CEP08797.1 - 1.7e-07 31.0 8.6 1.7e-07 31.0 8.6 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP08797.1 - 8.1e-05 22.4 9.3 0.0036 17.1 9.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 CEP08797.1 - 0.00017 21.3 0.0 0.00047 19.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 CEP08797.1 - 0.00086 19.6 11.8 0.002 18.4 11.8 1.7 1 0 0 1 1 1 1 Ring finger domain Nup35_RRM_2 PF14605.6 CEP08797.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CEP08797.1 - 0.022 14.6 11.0 0.046 13.6 11.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CEP08797.1 - 0.045 13.7 2.9 0.093 12.7 2.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) ROS_MUCR PF05443.11 CEP08797.1 - 0.048 13.7 0.3 0.19 11.8 0.0 2.1 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-C3HC4 PF00097.25 CEP08797.1 - 0.06 13.2 11.1 0.14 12.0 11.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP08797.1 - 0.13 12.4 6.6 0.29 11.2 5.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 CEP08797.1 - 0.35 11.0 6.7 0.072 13.2 2.8 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger Rtf2 PF04641.12 CEP08797.1 - 0.66 9.3 14.3 0.15 11.4 2.6 2.9 3 0 0 3 3 3 0 Rtf2 RING-finger DUF5385 PF17359.2 CEP08797.1 - 8.3 5.9 10.3 0.19 11.2 2.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) ABC2_membrane PF01061.24 CEP08798.1 - 3.9e-83 278.0 74.5 2.4e-47 161.1 23.3 3.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEP08798.1 - 3.6e-34 118.2 0.2 7.3e-18 65.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CEP08798.1 - 7e-27 93.2 1.5 4.3e-21 74.6 0.0 4.5 4 1 1 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP08798.1 - 2.6e-15 56.8 0.1 6.3e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 CEP08798.1 - 1.7e-05 24.8 0.2 0.042 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CEP08798.1 - 0.00026 21.1 0.0 0.14 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEP08798.1 - 0.00029 20.8 0.1 0.0067 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 CEP08798.1 - 0.00089 18.9 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP08798.1 - 0.0011 19.5 0.0 0.016 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP08798.1 - 0.0017 18.8 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CEP08798.1 - 0.004 16.9 0.4 0.022 14.5 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain FEZ PF07763.13 CEP08798.1 - 0.017 14.9 0.8 0.04 13.7 0.8 1.5 1 0 0 1 1 1 0 FEZ-like protein DnaB_C PF03796.15 CEP08798.1 - 0.027 13.8 0.0 0.68 9.2 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CEP08798.1 - 0.033 14.4 0.4 1.6 9.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CEP08798.1 - 0.049 13.3 0.4 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CEP08798.1 - 0.087 13.2 0.0 31 5.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CEP08798.1 - 0.11 12.6 0.3 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CEP08798.1 - 0.16 11.5 0.3 0.49 10.0 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEP08798.1 - 0.19 11.6 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_3 PF12698.7 CEP08798.1 - 0.28 10.3 71.1 0.082 12.0 34.0 4.2 2 2 2 4 4 4 0 ABC-2 family transporter protein DnaJ PF00226.31 CEP08799.1 - 4.4e-20 71.6 4.4 7.3e-20 70.9 4.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4407 PF14362.6 CEP08799.1 - 0.033 13.6 1.7 0.041 13.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosom_S12_S23 PF00164.25 CEP08800.1 - 5.7e-51 170.9 0.8 7.1e-51 170.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RT_RNaseH_2 PF17919.1 CEP08801.1 - 1.3e-36 124.6 0.0 3.3e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08801.1 - 3.5e-35 120.5 0.0 8.8e-35 119.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08801.1 - 3.6e-26 92.1 0.1 9e-26 90.8 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP08801.1 - 1.3e-16 60.9 0.0 7.2e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP08801.1 - 1.7e-16 60.1 0.2 5.5e-16 58.4 0.2 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CEP08801.1 - 1.8e-08 34.9 0.0 7.4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP08801.1 - 3.2e-08 34.0 0.0 1.1e-07 32.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP08801.1 - 1.6e-07 31.2 0.1 3.8e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CEP08801.1 - 8.3e-05 22.5 3.4 0.00017 21.5 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 CEP08801.1 - 0.00063 19.5 0.1 0.002 17.9 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 CEP08801.1 - 0.0061 16.3 0.0 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Serglycin PF04360.12 CEP08801.1 - 0.031 14.2 0.3 0.079 12.9 0.3 1.8 1 0 0 1 1 1 0 Serglycin DUF1758 PF05585.12 CEP08801.1 - 0.099 12.4 0.1 0.32 10.8 0.0 1.9 1 1 0 1 1 1 0 Putative peptidase (DUF1758) PAPS_reduct PF01507.19 CEP08802.1 - 1.2e-44 152.4 0.0 1.6e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MMS19_C PF12460.8 CEP08803.1 - 6.2e-97 325.4 36.6 1.1e-95 321.2 22.0 4.0 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CEP08803.1 - 1.4e-82 277.2 1.9 1.4e-82 277.2 1.9 4.6 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 CEP08803.1 - 0.018 15.4 0.2 7.3 7.1 0.0 4.3 4 1 1 5 5 5 0 HEAT repeats HEAT PF02985.22 CEP08803.1 - 0.031 14.5 0.0 44 4.7 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat UME PF08064.13 CEP08803.1 - 0.1 12.5 5.6 3.7 7.5 0.2 4.8 5 0 0 5 5 5 0 UME (NUC010) domain AAA PF00004.29 CEP08804.1 - 4.3e-41 140.4 0.0 1e-40 139.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEP08804.1 - 4.6e-16 58.5 0.0 9.1e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CEP08804.1 - 2.5e-09 36.8 0.2 6.4e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEP08804.1 - 1.3e-05 25.2 0.1 8.6e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP08804.1 - 1.9e-05 25.1 0.2 0.006 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP08804.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEP08804.1 - 0.00033 20.8 0.0 0.0025 17.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEP08804.1 - 0.00046 20.5 0.3 0.0093 16.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CEP08804.1 - 0.0015 17.7 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 CEP08804.1 - 0.0017 17.9 0.1 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 CEP08804.1 - 0.0021 17.9 0.4 0.38 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP08804.1 - 0.0052 16.9 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CEP08804.1 - 0.0054 16.1 0.1 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEP08804.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CEP08804.1 - 0.046 13.1 0.3 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 CEP08804.1 - 0.048 13.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CEP08804.1 - 0.059 12.9 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CEP08804.1 - 0.06 13.9 0.2 0.31 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CEP08804.1 - 0.084 12.6 0.0 0.32 10.7 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CEP08804.1 - 0.13 12.0 1.4 0.24 11.1 0.1 2.3 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CEP08804.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.15 CEP08804.1 - 0.41 10.4 3.0 0.68 9.7 1.9 2.0 1 1 0 1 1 1 0 Septum formation initiator FlxA PF14282.6 CEP08804.1 - 3.4 7.7 8.5 0.69 9.9 4.2 2.1 3 0 0 3 3 2 0 FlxA-like protein MTHFR PF02219.17 CEP08805.1 - 6.2e-116 386.7 0.0 8.3e-116 386.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DDE_3 PF13358.6 CEP08808.1 - 1.2e-24 86.7 0.1 6.7e-18 64.8 0.1 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP08808.1 - 0.00039 20.1 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain DUF1804 PF08822.11 CEP08808.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_32 PF13565.6 CEP08808.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEP08808.1 - 0.095 12.8 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 CEP08808.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-C2H2_2 PF12756.7 CEP08809.1 - 6.4e-17 61.7 62.6 0.00013 22.3 0.2 11.0 4 2 9 13 13 13 10 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CEP08809.1 - 5.6e-16 58.3 89.3 0.01 16.2 3.0 14.0 14 0 0 14 14 14 11 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CEP08809.1 - 0.0016 18.0 70.7 0.78 9.4 0.2 13.9 15 0 0 15 15 15 9 Zinc-fingers and homeoboxes C2H2 finger domain DUF3688 PF12461.8 CEP08809.1 - 0.035 12.5 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) zf-C2H2_jaz PF12171.8 CEP08809.1 - 0.06 13.6 0.4 0.06 13.6 0.4 13.2 14 0 0 14 14 14 0 Zinc-finger double-stranded RNA-binding Tox-GHH2 PF15635.6 CEP08810.1 - 0.076 13.5 1.0 0.17 12.4 1.0 1.7 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 TRAP_alpha PF03896.16 CEP08810.1 - 0.28 10.3 3.6 0.31 10.2 3.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1688 PF07958.11 CEP08811.1 - 4.1e-138 460.6 0.0 5.1e-138 460.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) zf-CCCH_4 PF18044.1 CEP08812.1 - 6.9e-08 32.1 1.7 1.3e-07 31.3 1.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEP08812.1 - 1.2e-05 25.2 4.4 2.1e-05 24.4 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEP08812.1 - 0.00014 21.7 1.0 0.00025 20.8 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEP08812.1 - 0.00033 21.3 0.3 0.0006 20.5 0.3 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CEP08812.1 - 0.75 10.4 2.8 1.3 9.6 2.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger KilA-N PF04383.13 CEP08813.1 - 0.097 12.5 0.1 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 KilA-N domain CpXC PF14353.6 CEP08813.1 - 0.13 12.3 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 CpXC protein SH3_7 PF12914.7 CEP08813.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain of SH3b2 type MGC-24 PF05283.11 CEP08815.1 - 0.0057 17.1 6.5 0.0057 17.1 6.5 2.7 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin LapA_dom PF06305.11 CEP08815.1 - 0.26 11.1 0.2 0.44 10.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 CEP08816.1 - 6e-82 275.8 0.0 8.1e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 CEP08817.1 - 0.00086 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP08817.1 - 0.019 14.8 0.0 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 F-box domain Pyridoxal_deC PF00282.19 CEP08817.1 - 0.026 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF4268 PF14088.6 CEP08818.1 - 0.0049 16.7 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4268) Pkinase PF00069.25 CEP08819.1 - 2.5e-55 187.7 1.3 8.9e-55 185.9 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08819.1 - 5.5e-40 137.3 0.0 1.1e-39 136.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CEP08819.1 - 2e-05 24.7 0.2 9.2e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Tropomyosin_1 PF12718.7 CEP08819.1 - 0.0097 16.1 15.4 0.021 15.0 15.4 1.6 1 0 0 1 1 1 1 Tropomyosin like GH114_assoc PF14741.6 CEP08819.1 - 0.026 14.8 0.0 0.55 10.4 0.1 2.9 2 1 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain Ferric_reduct PF01794.19 CEP08820.1 - 2.2e-18 66.6 7.6 4.8e-18 65.5 7.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEP08820.1 - 9.9e-12 45.2 0.0 3.4e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEP08820.1 - 6.6e-10 39.1 0.1 1.5e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CEP08820.1 - 0.00027 21.5 0.0 0.00083 20.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-CCHC_2 PF13696.6 CEP08823.1 - 0.0013 18.5 0.2 0.0019 18.0 0.2 1.2 1 0 0 1 1 1 1 Zinc knuckle HrpA_pilin PF09589.10 CEP08823.1 - 0.046 14.4 0.1 0.053 14.2 0.1 1.1 1 0 0 1 1 1 0 HrpA pilus formation protein PLDc_2 PF13091.6 CEP08824.1 - 8.3e-28 96.9 0.2 1.3e-27 96.2 0.2 1.3 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 CEP08824.1 - 0.0007 19.2 7.9 0.0022 17.6 1.1 2.7 2 1 0 2 2 2 1 FAM83 A-H PLDc PF00614.22 CEP08824.1 - 0.017 15.3 0.2 0.036 14.2 0.2 1.6 1 0 0 1 1 1 0 Phospholipase D Active site motif Ribosomal_60s PF00428.19 CEP08824.1 - 0.18 12.4 6.0 0.31 11.6 1.9 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein FYDLN_acid PF09538.10 CEP08824.1 - 4.1 8.1 9.0 0.97 10.1 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Umbravirus_LDM PF04817.12 CEP08824.1 - 9.4 5.5 7.9 8.9 5.6 1.4 2.2 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family 60KD_IMP PF02096.20 CEP08825.1 - 0.013 15.5 0.7 0.028 14.3 0.7 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein Zn-C2H2_12 PF18112.1 CEP08826.1 - 0.074 13.5 0.6 0.15 12.5 0.6 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain HLH PF00010.26 CEP08827.1 - 9.8e-20 70.3 0.5 9.8e-20 70.3 0.5 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2878 PF11086.8 CEP08831.1 - 0.01 16.0 0.6 0.01 16.0 0.6 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2878) DUF4231 PF14015.6 CEP08831.1 - 1.8 9.0 6.1 38 4.8 3.8 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Septin PF00735.18 CEP08832.1 - 2e-112 375.1 1.0 2.5e-112 374.8 1.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP08832.1 - 2.4e-11 43.7 0.4 6.8e-10 39.0 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP08832.1 - 9.8e-07 28.8 2.1 1.9e-06 27.9 0.6 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CEP08832.1 - 1.3e-06 27.9 0.1 2.6e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CEP08832.1 - 1.5e-05 24.6 0.2 0.00046 19.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CEP08832.1 - 0.0001 22.4 1.0 0.18 11.8 0.7 2.7 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 CEP08832.1 - 0.00051 20.3 0.1 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CEP08832.1 - 0.00064 19.2 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 CEP08832.1 - 0.00088 18.8 0.3 0.0028 17.2 0.2 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 CEP08832.1 - 0.00095 19.6 0.2 0.0034 17.8 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CEP08832.1 - 0.0024 18.4 0.8 0.0047 17.4 0.7 1.7 1 1 0 1 1 1 1 ABC transporter Ras PF00071.22 CEP08832.1 - 0.0042 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 CEP08832.1 - 0.0067 16.7 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEP08832.1 - 0.019 14.1 0.2 0.042 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 CEP08832.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 CEP08832.1 - 0.028 14.5 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEP08832.1 - 0.032 13.4 0.8 0.061 12.5 0.8 1.6 1 1 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CEP08832.1 - 0.037 13.1 0.3 0.08 12.0 0.3 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 CEP08832.1 - 0.038 13.0 0.1 0.082 12.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 CEP08832.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1542 PF07564.11 CEP08832.1 - 0.06 13.5 3.0 0.1 12.8 0.1 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Sigma54_activat PF00158.26 CEP08832.1 - 0.083 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 CEP08832.1 - 0.088 12.5 0.4 0.4 10.4 0.4 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CEP08832.1 - 0.11 11.6 1.0 0.24 10.5 1.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 CEP08832.1 - 0.15 12.2 0.4 0.86 9.8 0.4 2.4 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 CEP08833.1 - 9.3e-64 214.9 18.5 2.5e-63 213.4 18.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEP08833.1 - 6.6e-26 90.9 0.0 2.3e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CEP08833.1 - 1.7e-15 57.6 1.3 2.4e-07 30.9 0.3 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEP08833.1 - 2e-09 37.6 14.7 2e-09 37.6 14.7 5.3 2 2 1 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 CEP08833.1 - 8.2e-08 31.9 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 CEP08833.1 - 0.0054 16.8 3.6 0.0054 16.8 3.6 8.2 5 3 3 8 8 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 CEP08833.1 - 0.0066 16.3 9.3 0.0066 16.3 9.3 6.9 5 2 2 7 7 7 2 Protein of unknown function (DUF724) AAA_23 PF13476.6 CEP08833.1 - 0.011 16.3 108.5 1.9 8.9 59.9 6.8 3 2 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 CEP08833.1 - 0.012 15.8 0.0 0.052 13.8 0.0 2.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Apo-CIII PF05778.12 CEP08833.1 - 0.07 12.8 0.0 0.64 9.7 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) ABC_tran PF00005.27 CEP08833.1 - 0.078 13.5 0.0 0.12 12.9 0.0 5.6 4 3 0 4 4 3 0 ABC transporter DUF1482 PF07358.11 CEP08833.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) zf-ZPR1 PF03367.13 CEP08834.1 - 3.1e-113 374.9 0.5 1.2e-56 191.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CEP08834.1 - 0.01 15.9 3.5 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RFX5_N PF18326.1 CEP08834.1 - 0.044 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 RFX5 N-terminal domain NigD_N PF12667.7 CEP08834.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 NigD-like N-terminal OB domain DZR PF12773.7 CEP08834.1 - 0.76 9.8 10.8 2.2 8.4 2.8 3.3 2 2 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CEP08834.1 - 0.9 9.6 5.6 4 7.5 1.5 2.6 2 1 0 2 2 2 0 zinc-ribbons UPF0547 PF10571.9 CEP08834.1 - 1.1 9.4 9.9 1.3 9.2 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 C1_1 PF00130.22 CEP08834.1 - 2.9 7.8 5.6 2.6 8.0 1.1 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CEP08835.1 - 4.6e-16 59.0 0.6 7.9e-16 58.2 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08835.1 - 0.00018 20.9 0.1 0.00028 20.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Csm1 PF12539.8 CEP08835.1 - 0.064 13.9 0.3 0.86 10.3 0.0 2.8 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Syndecan PF01034.20 CEP08835.1 - 0.073 13.0 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 CEP08835.1 - 0.083 13.5 0.2 0.3 11.7 0.2 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage CRA PF06589.11 CEP08836.1 - 0.5 10.5 6.1 3.5 7.7 0.6 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) UCH PF00443.29 CEP08837.1 - 1.8e-48 165.3 0.3 3.2e-48 164.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP08837.1 - 3.2e-19 69.7 0.0 1.2e-18 67.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CEP08837.1 - 5.5e-09 36.2 1.1 1.8e-08 34.5 0.1 2.3 2 1 0 2 2 2 1 MATH domain GlcV_C_terminal PF17847.1 CEP08837.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Glucose ABC transporter C-terminal domain RTC4 PF14474.6 CEP08838.1 - 1.9e-23 82.9 0.1 4.2e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 RTC4-like domain CpXC PF14353.6 CEP08838.1 - 0.036 14.1 0.2 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 CpXC protein MIF4G_like_2 PF09090.11 CEP08839.1 - 3e-72 243.3 7.4 4.3e-72 242.8 7.4 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 CEP08839.1 - 1.7e-54 184.5 0.1 4.2e-54 183.2 0.1 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CEP08839.1 - 5.5e-13 49.0 0.2 4.7e-12 46.0 0.1 2.4 3 0 0 3 3 3 1 MIF4G domain Macscav_rec PF03523.13 CEP08839.1 - 0.048 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Macrophage scavenger receptor HAUS6_N PF14661.6 CEP08840.1 - 4.7e-14 52.5 2.7 7.5e-14 51.9 2.7 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus zf-CCCH_2 PF14608.6 CEP08841.1 - 1.5e-11 44.3 27.1 8.1e-06 26.1 5.4 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Mt_ATP-synt_B PF05405.14 CEP08841.1 - 3.4 7.3 7.6 0.38 10.3 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ras PF00071.22 CEP08842.1 - 2.5e-61 206.0 0.1 3e-61 205.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08842.1 - 6e-35 120.1 0.1 9.2e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08842.1 - 4.1e-13 49.1 0.0 5.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP08842.1 - 1.2e-06 28.6 0.1 2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CEP08842.1 - 0.00014 22.2 0.0 0.001 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CEP08842.1 - 0.00019 21.4 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEP08842.1 - 0.0013 18.3 0.2 0.007 15.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEP08842.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEP08842.1 - 0.0025 17.2 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CEP08842.1 - 0.003 16.4 0.1 0.033 13.0 0.1 2.0 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 CEP08842.1 - 0.004 16.9 0.0 0.0079 15.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain FAD-SLDH PF12318.8 CEP08842.1 - 0.0082 16.2 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_16 PF13191.6 CEP08842.1 - 0.014 15.8 0.1 0.022 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CEP08842.1 - 0.015 14.7 0.0 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein DUF4623 PF15416.6 CEP08842.1 - 0.019 13.6 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) ABC_tran PF00005.27 CEP08842.1 - 0.021 15.3 0.0 0.028 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CEP08842.1 - 0.024 14.6 0.1 0.058 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CEP08842.1 - 0.031 13.8 0.2 0.082 12.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_32 PF13654.6 CEP08842.1 - 0.037 12.8 0.0 0.092 11.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CEP08842.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CEP08842.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 CEP08842.1 - 0.055 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 CEP08842.1 - 0.074 12.6 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CEP08842.1 - 0.13 12.1 0.2 0.31 10.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CEP08842.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 CEP08842.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pex24p PF06398.11 CEP08843.1 - 7.8e-25 87.6 16.1 1.2e-24 87.0 16.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Nucleoside_tran PF01733.18 CEP08844.1 - 9.3e-18 64.6 13.5 9.3e-18 64.6 13.5 2.8 2 1 1 3 3 3 2 Nucleoside transporter HTH_psq PF05225.16 CEP08845.1 - 4.9e-07 29.4 0.0 2e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP08845.1 - 1.5e-05 25.0 0.8 4.1e-05 23.6 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CEP08845.1 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain DDE_3 PF13358.6 CEP08845.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP08845.1 - 0.0055 16.5 0.1 0.016 15.0 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain FeoC PF09012.10 CEP08845.1 - 0.0096 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_32 PF13565.6 CEP08845.1 - 0.012 16.2 0.9 0.084 13.5 0.0 2.6 2 1 1 3 3 3 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP08845.1 - 0.014 14.8 0.0 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 CEP08845.1 - 0.028 14.5 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 CEP08845.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Snapin_Pallidin PF14712.6 CEP08847.1 - 0.018 15.4 0.3 0.045 14.2 0.3 1.6 1 0 0 1 1 1 0 Snapin/Pallidin DUF4101 PF13355.6 CEP08847.1 - 0.046 14.2 0.7 0.087 13.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) DUF3888 PF13027.6 CEP08847.1 - 0.13 12.7 1.4 0.4 11.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) NDT80_PhoG PF05224.12 CEP08848.1 - 2.8e-35 122.2 2.3 3.7e-35 121.8 0.1 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family RRM_1 PF00076.22 CEP08849.1 - 9e-08 31.8 0.0 2.7e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CEP08849.1 - 0.00036 20.3 13.6 0.053 13.4 10.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP08849.1 - 8 6.4 16.8 0.84 9.6 11.4 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PNP_UDP_1 PF01048.20 CEP08850.1 - 1.5e-41 142.2 0.0 1.7e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Bac_DNA_binding PF00216.21 CEP08850.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA-binding protein Acetyltransf_10 PF13673.7 CEP08851.1 - 4.5e-10 39.6 0.0 5.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP08851.1 - 5.2e-08 33.1 0.0 6.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP08851.1 - 1.1e-07 32.1 0.3 1.8e-07 31.5 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEP08851.1 - 5.5e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUP PF00674.18 CEP08851.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 DUP family ERCC3_RAD25_C PF16203.5 CEP08851.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Thioredoxin PF00085.20 CEP08852.1 - 3.2e-29 100.9 0.2 3.8e-29 100.7 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEP08852.1 - 5.3e-07 30.1 0.2 6.8e-06 26.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP08852.1 - 4e-06 27.1 0.0 8.4e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CEP08852.1 - 0.00015 21.2 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CEP08852.1 - 0.0002 21.5 0.2 0.00056 20.0 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEP08852.1 - 0.00064 19.5 0.0 0.00076 19.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CEP08852.1 - 0.00074 19.4 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 CEP08852.1 - 0.0034 17.1 0.0 0.0041 16.9 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 CEP08852.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 CEP08852.1 - 0.013 15.3 0.2 0.018 14.7 0.2 1.4 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 CEP08852.1 - 0.021 14.7 0.1 0.045 13.6 0.0 1.5 1 1 1 2 2 2 0 F plasmid transfer operon protein Phosducin PF02114.16 CEP08852.1 - 0.04 12.8 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.24 CEP08852.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin SAP PF02037.27 CEP08853.1 - 3.8e-09 36.1 0.3 6.3e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 SAP domain UPF0242 PF06785.11 CEP08853.1 - 1.8 8.6 12.3 2.8 8.0 9.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BBP1_N PF15271.6 CEP08853.1 - 2.4 8.9 10.4 1.5 9.6 7.1 2.3 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DUF4574 PF15141.6 CEP08853.1 - 7.3 6.6 6.6 18 5.3 2.1 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SNARE PF05739.19 CEP08854.1 - 8.9e-09 35.2 0.2 8.9e-09 35.2 0.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 CEP08854.1 - 5.4e-06 25.5 0.1 1.6e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 CEP08854.1 - 0.0054 16.4 1.8 0.0054 16.4 1.8 3.6 3 1 1 4 4 4 1 Syntaxin Syntaxin-18_N PF10496.9 CEP08854.1 - 0.0086 16.3 0.4 0.0086 16.3 0.4 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Senescence PF06911.12 CEP08854.1 - 0.066 13.5 0.9 0.16 12.3 0.8 1.7 1 1 0 1 1 1 0 Senescence-associated protein DUF4988 PF16378.5 CEP08854.1 - 0.11 12.1 2.7 4.2 7.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF16 PF01519.16 CEP08854.1 - 0.14 12.6 9.9 0.66 10.5 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Romo1 PF10247.9 CEP08854.1 - 0.56 10.6 2.3 1.1 9.6 2.3 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF948 PF06103.11 CEP08854.1 - 0.93 9.8 10.3 7.3 6.9 0.2 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 CEP08854.1 - 2.7 8.2 14.9 0.24 11.6 3.1 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein LPP PF04728.13 CEP08854.1 - 3.2 8.2 6.0 14 6.1 1.2 3.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NPV_P10 PF05531.12 CEP08854.1 - 4.9 7.7 10.0 22 5.6 0.8 3.7 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein YscO PF07321.12 CEP08854.1 - 5 7.1 8.6 4.6 7.2 0.4 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO FlaC_arch PF05377.11 CEP08854.1 - 7.6 7.0 8.8 2.7 8.4 0.7 3.6 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 CEP08854.1 - 9.4 6.9 15.1 1.2 9.8 0.8 4.0 2 2 1 3 3 3 0 SlyX UCH PF00443.29 CEP08855.1 - 3.3e-42 144.7 6.4 4.7e-41 141.0 6.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CEP08855.1 - 6.4e-19 67.6 1.8 9.3e-13 47.9 0.1 3.3 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 CEP08855.1 - 0.00017 21.3 15.8 0.012 15.3 0.1 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 CEP08855.1 - 0.0028 17.6 0.0 0.0095 15.9 0.0 2.0 1 0 0 1 1 1 1 PUB domain DUF745 PF05335.13 CEP08855.1 - 1.1 9.0 5.0 3.8 7.2 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Cu_amine_oxid PF01179.20 CEP08856.1 - 5.1e-26 91.5 2.2 6.1e-26 91.3 2.2 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain FAD_binding_1 PF00667.20 CEP08857.1 - 4.8e-57 193.1 0.0 7.7e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP08857.1 - 1e-34 119.8 1.5 1.4e-34 119.4 0.5 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CEP08857.1 - 4.5e-19 69.1 0.0 1.3e-18 67.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SOG2 PF10428.9 CEP08858.1 - 5.7e-35 121.5 15.8 1.6e-24 87.1 2.2 2.5 2 1 1 3 3 3 2 RAM signalling pathway protein Oxidored-like PF09791.9 CEP08858.1 - 5.6e-11 41.9 1.1 1.2e-10 40.9 1.1 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Focal_AT PF03623.13 CEP08858.1 - 0.2 11.7 4.0 34 4.4 0.0 3.8 4 0 0 4 4 4 0 Focal adhesion targeting region WW PF00397.26 CEP08859.1 - 5.6e-05 23.1 0.2 5.6e-05 23.1 0.2 2.7 3 0 0 3 3 3 1 WW domain DUF3294 PF07957.11 CEP08859.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Na_H_Exchanger PF00999.21 CEP08860.1 - 1.6e-51 175.3 27.9 2.2e-51 174.8 27.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 CEP08860.1 - 0.9 9.7 7.6 0.24 11.5 0.3 3.3 4 0 0 4 4 4 0 YrhC-like protein Pkinase PF00069.25 CEP08861.1 - 1.3e-39 136.1 0.3 5.2e-39 134.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08861.1 - 1e-13 51.2 1.4 9.9e-11 41.4 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CEP08861.1 - 0.01 15.8 0.0 0.049 13.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family ApbA_C PF08546.11 CEP08861.1 - 0.096 12.9 0.9 1.1 9.5 1.6 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF740 PF05340.12 CEP08861.1 - 1.3 7.7 8.0 2 7.1 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) FTA2 PF13095.6 CEP08861.1 - 4.1 7.0 7.4 8.2 6.0 0.0 3.1 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 LCIB_C_CA PF18599.1 CEP08861.1 - 8.8 5.6 6.4 16 4.7 6.4 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Exo_endo_phos PF03372.23 CEP08862.1 - 2.5e-19 69.8 0.0 3.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3760 PF12586.8 CEP08863.1 - 0.016 15.3 0.7 0.66 10.2 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) LRR_4 PF12799.7 CEP08863.1 - 3.2 8.3 9.5 24 5.5 0.7 5.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) PIF1 PF05970.14 CEP08864.1 - 1.7e-13 50.5 0.0 1.9e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Spt20 PF12090.8 CEP08866.1 - 1.4 8.5 13.5 1.6 8.3 13.5 1.1 1 0 0 1 1 1 0 Spt20 family SBE2 PF17076.5 CEP08867.1 - 9.3 4.3 17.5 12 3.9 17.5 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation PIF1 PF05970.14 CEP08869.1 - 3.3e-13 49.5 0.1 3.6e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase 40S_S4_C PF16121.5 CEP08869.1 - 0.02 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus PIF1 PF05970.14 CEP08870.1 - 5.9e-43 147.4 0.0 6.7e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP08870.1 - 1.8e-09 37.6 0.0 2.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP08870.1 - 0.00061 20.1 0.0 0.00098 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP08870.1 - 0.0008 19.8 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP08870.1 - 0.0092 15.3 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 CEP08870.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP08870.1 - 0.025 15.0 0.0 0.025 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 CEP08870.1 - 0.039 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CEP08870.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CEP08870.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF1604 PF07713.13 CEP08872.1 - 0.61 9.9 8.5 0.43 10.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1604) zf-CCHC PF00098.23 CEP08873.1 - 7.5e-06 25.8 2.8 1.1e-05 25.2 2.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEP08873.1 - 0.0011 18.8 0.9 0.0011 18.8 0.9 1.6 2 0 0 2 2 2 1 Zinc knuckle DUF3725 PF12523.8 CEP08873.1 - 0.031 14.6 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) DUF3984 PF13136.6 CEP08874.1 - 0.072 12.5 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RVT_1 PF00078.27 CEP08875.1 - 8.3e-40 136.7 0.0 1.6e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP08875.1 - 5.3e-07 30.3 0.9 1.2e-06 29.1 0.4 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Retrotrans_gag PF03732.17 CEP08876.1 - 7.5e-06 26.1 1.9 1.2e-05 25.5 0.4 2.1 2 2 0 2 2 2 1 Retrotransposon gag protein TerB PF05099.13 CEP08876.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB Retrotran_gag_2 PF14223.6 CEP08876.1 - 0.035 13.8 2.3 0.045 13.4 0.6 2.0 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF1086 PF06461.11 CEP08876.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Uds1 PF15456.6 CEP08876.1 - 0.21 11.7 1.2 0.46 10.7 0.3 1.9 2 1 0 2 2 2 0 Up-regulated During Septation BNIP3 PF06553.12 CEP08877.1 - 2.2e-05 24.2 1.7 3e-05 23.8 1.7 1.2 1 0 0 1 1 1 1 BNIP3 SR-25 PF10500.9 CEP08877.1 - 0.013 15.1 9.0 0.018 14.6 9.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_fiss_reg PF05308.11 CEP08877.1 - 0.027 14.6 14.4 0.037 14.1 14.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Zip PF02535.22 CEP08877.1 - 0.082 12.1 1.4 0.085 12.1 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 CEP08877.1 - 0.17 11.8 18.7 0.21 11.6 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 CEP08877.1 - 0.22 8.6 7.1 0.23 8.6 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 CEP08877.1 - 0.28 9.9 11.7 0.38 9.5 11.7 1.1 1 0 0 1 1 1 0 Presenilin API5 PF05918.11 CEP08877.1 - 0.37 9.6 11.1 0.46 9.2 11.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Neur_chan_memb PF02932.16 CEP08877.1 - 0.49 10.4 5.2 0.62 10.1 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 CEP08877.1 - 0.6 8.7 8.5 0.63 8.7 8.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWI-SNF_Ssr4 PF08549.10 CEP08877.1 - 0.64 8.6 13.1 0.84 8.2 13.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) GEN1_C PF18380.1 CEP08877.1 - 1 10.3 8.4 0.28 12.1 4.0 2.0 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Suf PF05843.14 CEP08877.1 - 1.3 8.9 14.0 1.8 8.5 14.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.12 CEP08877.1 - 1.4 8.7 8.9 1.9 8.3 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 CEP08877.1 - 2 8.1 9.1 2.8 7.7 9.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 CEP08877.1 - 2.3 7.1 11.0 2.7 6.9 11.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CEP08877.1 - 2.7 8.2 11.5 4.6 7.5 11.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 CEP08877.1 - 2.9 7.4 26.0 4.3 6.9 26.0 1.2 1 0 0 1 1 1 0 Spt20 family ALMT PF11744.8 CEP08877.1 - 3 6.6 7.4 3.6 6.3 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3533 PF12051.8 CEP08877.1 - 3.8 6.3 7.4 4.8 6.0 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TMEM247 PF15444.6 CEP08878.1 - 0.03 14.4 2.9 1.1 9.3 2.8 2.1 1 1 0 1 1 1 0 Transmembrane protein 247 Tht1 PF04163.12 CEP08878.1 - 0.17 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein AOX PF01786.17 CEP08879.1 - 0.02 14.5 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Alternative oxidase RT_RNaseH_2 PF17919.1 CEP08880.1 - 1.6e-25 89.0 0.0 2.6e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08880.1 - 1.2e-14 54.5 0.0 2.2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08880.1 - 3.3e-05 23.5 0.1 4.6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH_3 PF14593.6 CEP08880.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 PH domain NDC10_II PF16787.5 CEP08881.1 - 7.4e-42 143.5 0.4 1.8e-22 79.9 0.0 2.4 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP08881.1 - 5.8e-19 68.2 3.4 1.9e-18 66.5 3.4 2.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.11 CEP08881.1 - 0.012 15.8 2.4 0.017 15.3 0.9 2.1 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Phage_integrase PF00589.22 CEP08881.1 - 0.029 14.2 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family C2 PF00168.30 CEP08882.1 - 2.8e-19 69.3 0.1 8.6e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 CEP08882.1 - 1.2e-15 57.9 8.2 4.4e-10 39.9 3.0 3.6 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 CEP08882.1 - 5.1e-08 31.9 5.5 2.4e-06 26.4 0.0 3.6 4 0 0 4 4 4 2 Plant family of unknown function (DUF810) HSP70 PF00012.20 CEP08883.1 - 2.1e-07 29.6 0.0 1.9e-05 23.1 0.0 2.3 2 1 0 2 2 2 2 Hsp70 protein Pkinase PF00069.25 CEP08884.1 - 1.2e-68 231.3 0.1 2.3e-68 230.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08884.1 - 1.1e-35 123.2 0.0 2.5e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEP08884.1 - 2.5e-21 75.2 0.2 5.3e-21 74.1 0.2 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CEP08884.1 - 2.9e-06 26.8 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP08884.1 - 0.0001 21.4 0.1 0.0001 21.4 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CEP08884.1 - 0.00036 19.9 0.1 0.00089 18.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP08884.1 - 0.0024 17.8 2.5 0.0063 16.5 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEP08884.1 - 0.0057 16.3 0.6 0.016 14.8 0.6 1.7 1 1 0 1 1 1 1 RIO1 family Lipase_GDSL PF00657.22 CEP08885.1 - 1.4e-16 61.0 0.0 2.1e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP08885.1 - 3.3e-08 34.1 0.0 8.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Retrotrans_gag PF03732.17 CEP08887.1 - 1e-14 54.6 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein HTH_30 PF13556.6 CEP08888.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RVT_1 PF00078.27 CEP08889.1 - 8.6e-22 77.7 0.2 1.5e-20 73.7 0.0 2.5 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CEP08889.1 - 0.001 18.7 0.2 0.0022 17.6 0.2 1.5 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RNase_H PF00075.24 CEP08889.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 RNase H Ipi1_N PF12333.8 CEP08889.1 - 0.043 14.4 0.7 0.11 13.1 0.1 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Adhes-Ig_like PF09085.10 CEP08892.1 - 0.17 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like Retrotrans_gag PF03732.17 CEP08893.1 - 1.1e-05 25.7 0.1 0.0042 17.3 0.0 2.2 1 1 1 2 2 2 2 Retrotransposon gag protein Zn-ribbon_8 PF09723.10 CEP08895.1 - 0.0034 17.5 1.1 1.2 9.4 0.1 3.4 3 0 0 3 3 3 1 Zinc ribbon domain zf-Dof PF02701.15 CEP08895.1 - 0.056 13.6 2.3 0.16 12.2 1.2 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger Sgf11 PF08209.11 CEP08895.1 - 0.067 12.8 2.7 3.5 7.3 0.5 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_10 PF10058.9 CEP08895.1 - 0.12 12.2 5.0 8.8 6.1 0.2 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4065 PF13274.6 CEP08895.1 - 0.2 12.6 4.3 0.83 10.6 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) PHD_Oberon PF07227.11 CEP08895.1 - 0.22 11.4 5.8 0.78 9.6 0.8 2.5 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein zf-C2H2_11 PF16622.5 CEP08895.1 - 0.23 11.2 2.1 4.4 7.2 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type LMBR1 PF04791.16 CEP08895.1 - 0.24 10.2 4.5 0.27 10.1 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Zn_Tnp_IS1595 PF12760.7 CEP08895.1 - 0.36 10.8 6.3 2.2 8.3 1.2 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2992 PF11208.8 CEP08895.1 - 2.4 8.4 9.6 6.9 6.9 9.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) C1_4 PF07975.12 CEP08895.1 - 2.9 8.2 8.4 1.8 8.9 0.7 3.2 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 CEP08895.1 - 5.4 7.0 14.0 0.41 10.6 0.9 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RVT_1 PF00078.27 CEP08896.1 - 3.1e-24 85.7 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0492 PF15744.5 CEP08896.1 - 0.12 11.6 0.3 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0492 RT_RNaseH_2 PF17919.1 CEP08897.1 - 1.5e-28 98.8 0.0 2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08897.1 - 3.7e-22 78.6 0.0 5.1e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pepsin-I3 PF06394.13 CEP08897.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain ZapB PF06005.12 CEP08898.1 - 0.00013 22.4 32.3 0.34 11.4 6.2 4.6 2 1 2 4 4 4 2 Cell division protein ZapB YabA PF06156.13 CEP08898.1 - 0.00014 22.4 27.3 0.00024 21.7 4.7 3.5 1 1 2 3 3 3 1 Initiation control protein YabA bZIP_1 PF00170.21 CEP08898.1 - 0.00039 20.4 14.7 0.14 12.3 0.3 4.0 3 1 1 4 4 4 2 bZIP transcription factor KASH_CCD PF14662.6 CEP08898.1 - 0.00076 19.4 29.7 0.017 15.0 17.2 3.0 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH Tropomyosin PF00261.20 CEP08898.1 - 0.00096 18.6 14.2 0.00096 18.6 14.2 1.9 1 1 1 2 2 2 1 Tropomyosin APG6_N PF17675.1 CEP08898.1 - 0.0015 19.0 34.7 0.024 15.2 13.5 3.2 1 1 2 3 3 3 1 Apg6 coiled-coil region ERM PF00769.19 CEP08898.1 - 0.0053 16.6 17.2 0.0053 16.6 17.2 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Spc7 PF08317.11 CEP08898.1 - 0.0061 15.5 28.1 0.073 11.9 17.4 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein GIT_CC PF16559.5 CEP08898.1 - 0.0082 16.0 27.3 0.0085 15.9 4.4 4.7 4 1 1 5 5 5 2 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 CEP08898.1 - 0.014 15.8 29.0 0.016 15.6 4.3 3.5 1 1 2 3 3 3 0 Centromere protein H (CENP-H) TSC22 PF01166.18 CEP08898.1 - 0.019 15.3 19.1 0.26 11.6 1.7 4.9 3 2 1 4 4 4 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 CEP08898.1 - 0.02 15.0 8.3 0.02 15.0 8.3 3.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 ABC_tran_Xtn PF12848.7 CEP08898.1 - 0.021 14.9 0.2 0.021 14.9 0.2 2.7 2 1 0 2 2 2 0 ABC transporter F_actin_bind PF08919.10 CEP08898.1 - 0.04 14.0 14.4 1.4 9.1 1.8 3.4 2 2 0 2 2 2 0 F-actin binding PspA_IM30 PF04012.12 CEP08898.1 - 0.048 13.2 22.7 0.097 12.2 12.8 2.4 2 1 0 2 2 2 0 PspA/IM30 family DUF812 PF05667.11 CEP08898.1 - 0.053 12.4 29.7 0.12 11.2 27.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Herpes_BLRF2 PF05812.12 CEP08898.1 - 0.057 13.6 15.6 0.45 10.7 6.2 2.7 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Shugoshin_N PF07558.11 CEP08898.1 - 0.068 13.0 20.0 1.5 8.7 1.9 3.9 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF848 PF05852.11 CEP08898.1 - 0.069 13.3 18.5 0.12 12.5 2.6 3.0 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_2 PF07716.15 CEP08898.1 - 0.069 13.2 19.3 0.72 10.0 0.8 4.0 3 1 0 3 3 3 0 Basic region leucine zipper Filament PF00038.21 CEP08898.1 - 0.16 11.5 26.9 0.29 10.7 14.6 3.0 1 1 2 3 3 3 0 Intermediate filament protein ADIP PF11559.8 CEP08898.1 - 0.17 12.0 36.1 0.37 10.9 4.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SIKE PF05769.11 CEP08898.1 - 0.17 11.8 24.3 6.5 6.6 0.6 4.1 1 1 0 2 2 2 0 SIKE family BRE1 PF08647.11 CEP08898.1 - 0.22 11.6 23.7 0.24 11.5 5.9 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Leu_zip PF15294.6 CEP08898.1 - 0.22 11.0 25.0 0.6 9.6 2.3 2.5 1 1 1 2 2 2 0 Leucine zipper Lebercilin PF15619.6 CEP08898.1 - 0.26 10.9 31.4 0.09 12.4 12.4 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 CEP08898.1 - 0.27 11.2 24.7 0.79 9.8 7.5 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 CEP08898.1 - 0.33 10.4 31.7 0.11 12.0 16.6 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 DivIC PF04977.15 CEP08898.1 - 0.51 10.1 24.3 0.98 9.2 1.9 4.5 3 1 2 5 5 4 0 Septum formation initiator FlaC_arch PF05377.11 CEP08898.1 - 0.52 10.7 20.9 1.8 9.0 0.6 5.0 4 2 1 5 5 4 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 CEP08898.1 - 0.59 9.6 41.7 0.19 11.2 29.5 3.2 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain DUF5339 PF17274.2 CEP08898.1 - 0.66 10.9 6.1 2.9 8.8 0.1 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DUF4407 PF14362.6 CEP08898.1 - 0.66 9.3 20.8 19 4.5 20.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mto2_bdg PF12808.7 CEP08898.1 - 0.8 10.1 14.0 0.8 10.0 2.2 3.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GAS PF13851.6 CEP08898.1 - 0.99 8.7 27.1 0.059 12.7 8.4 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.13 CEP08898.1 - 1 10.0 12.9 0.08 13.6 2.8 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) CCDC-167 PF15188.6 CEP08898.1 - 1 9.8 22.7 0.16 12.3 11.9 3.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 PRKG1_interact PF15898.5 CEP08898.1 - 1.3 10.0 30.5 0.88 10.5 13.2 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 CEP08898.1 - 1.4 9.4 29.2 2 8.9 15.3 2.7 1 1 2 3 3 3 0 Fez1 Rootletin PF15035.6 CEP08898.1 - 1.7 8.6 35.3 0.81 9.7 22.1 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prefoldin PF02996.17 CEP08898.1 - 2 8.4 19.0 1 9.3 1.8 3.8 3 1 1 4 4 4 0 Prefoldin subunit TMF_TATA_bd PF12325.8 CEP08898.1 - 2.6 8.3 31.7 0.65 10.2 4.0 3.7 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 CEP08898.1 - 2.9 7.9 31.7 24 4.9 5.4 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CEP08898.1 - 3 8.0 35.7 0.15 12.3 26.7 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 CEP08898.1 - 3.5 6.7 31.6 7.1 5.7 17.5 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TACC_C PF05010.14 CEP08898.1 - 3.7 7.3 25.2 2.3 7.9 5.6 3.1 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Jnk-SapK_ap_N PF09744.9 CEP08898.1 - 3.9 7.7 33.1 22 5.2 14.0 3.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 CEP08898.1 - 4.4 7.1 18.5 4.3 7.1 5.1 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) EspB_PE PF18625.1 CEP08898.1 - 4.5 7.8 8.1 0.77 10.3 0.9 3.0 3 1 1 4 4 3 0 ESX-1 secreted protein B PE domain HIP1_clath_bdg PF16515.5 CEP08898.1 - 5.1 7.8 32.3 0.21 12.2 14.8 3.5 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CEP08898.1 - 5.6 7.1 32.7 2.6 8.1 17.5 3.8 1 1 2 3 3 2 0 TPR/MLP1/MLP2-like protein YojJ PF10372.9 CEP08898.1 - 6 7.0 9.2 0.53 10.4 0.8 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Syntaxin-6_N PF09177.11 CEP08898.1 - 6.7 7.3 24.8 3.5 8.2 8.1 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 CEP08898.1 - 6.7 6.9 22.1 2.7 8.2 7.1 4.0 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Prefoldin_2 PF01920.20 CEP08898.1 - 6.8 6.7 23.0 0.43 10.6 2.5 3.8 3 1 0 3 3 3 0 Prefoldin subunit BST2 PF16716.5 CEP08898.1 - 7.4 7.2 29.6 0.83 10.3 3.8 3.5 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 DDE_3 PF13358.6 CEP08900.1 - 6e-28 97.4 0.0 1.3e-19 70.4 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 CEP08900.1 - 0.00088 19.8 0.0 0.0027 18.3 0.0 1.9 2 1 0 2 2 2 1 Homeodomain-like domain Peroxin-3 PF04882.12 CEP08901.1 - 7.9e-131 437.3 2.5 9.5e-131 437.0 2.5 1.1 1 0 0 1 1 1 1 Peroxin-3 Anp1 PF03452.14 CEP08902.1 - 6.4e-56 189.7 1.9 7.8e-56 189.4 1.9 1.1 1 0 0 1 1 1 1 Anp1 SWIRM PF04433.17 CEP08903.1 - 2.5e-08 34.1 0.0 4.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 SWIRM domain DUF4735 PF15882.5 CEP08904.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) RVT_1 PF00078.27 CEP08908.1 - 1.4e-06 28.0 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLATT_4 PF18186.1 CEP08909.1 - 0.034 13.8 0.6 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 FWWh PF14922.6 CEP08909.1 - 0.082 12.8 0.0 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function Retrotrans_gag PF03732.17 CEP08909.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein SANTA PF09133.10 CEP08909.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 SANTA (SANT Associated) RVT_1 PF00078.27 CEP08910.1 - 4.5e-15 55.8 1.5 6.9e-15 55.2 0.1 2.0 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CEP08910.1 - 0.0025 18.0 0.1 0.0062 16.7 0.1 1.7 1 0 0 1 1 1 1 RNase H RT_RNaseH_2 PF17919.1 CEP08910.1 - 0.052 13.6 0.0 0.23 11.5 0.0 2.1 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08910.1 - 0.21 11.9 2.6 1.1 9.6 0.1 2.9 2 1 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CEP08911.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 CEP08912.1 - 1.3e-36 124.6 0.0 3.6e-36 123.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP08912.1 - 2.7e-33 114.4 0.0 7.1e-33 113.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP08912.1 - 4e-22 78.8 0.4 1e-21 77.5 0.4 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 CEP08912.1 - 1.2e-10 41.5 2.6 1.2e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP08912.1 - 0.00023 21.7 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP08912.1 - 0.0006 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP08912.1 - 0.0018 18.0 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEP08912.1 - 0.15 12.3 0.0 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease RNA_pol_Rpb1_1 PF04997.12 CEP08913.1 - 5.2e-92 308.5 0.0 8.3e-92 307.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CEP08913.1 - 3.6e-83 279.1 0.8 5.4e-83 278.5 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEP08913.1 - 1.3e-73 246.7 0.1 3.6e-73 245.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEP08913.1 - 3.7e-37 127.7 0.0 3.7e-36 124.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CEP08913.1 - 2.4e-31 107.9 0.2 7.8e-31 106.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 CEP08913.1 - 9.7 6.6 6.3 16 5.9 1.2 2.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arm-DNA-bind_4 PF14657.6 CEP08915.1 - 0.24 11.2 1.9 0.62 9.9 1.9 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain zf-CCHC_5 PF14787.6 CEP08915.1 - 1.8 8.4 5.7 1.2 8.9 0.5 2.9 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger HTH_23 PF13384.6 CEP08916.1 - 3e-06 26.9 0.0 9.5e-06 25.3 0.0 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP08916.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_29 PF13551.6 CEP08916.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_psq PF05225.16 CEP08916.1 - 0.093 12.5 0.4 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain RRM_1 PF00076.22 CEP08917.1 - 1.1e-15 57.1 0.0 1.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FTA4 PF13093.6 CEP08917.1 - 0.0084 16.0 1.5 0.0099 15.8 1.5 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 CEP08917.1 - 0.02 15.4 11.9 0.024 15.2 11.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3987 PF13148.6 CEP08917.1 - 0.084 11.9 2.6 0.11 11.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Lge1 PF11488.8 CEP08917.1 - 0.099 12.8 3.9 1.5 9.0 5.4 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 DivIC PF04977.15 CEP08917.1 - 0.12 12.2 4.8 0.22 11.3 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Uds1 PF15456.6 CEP08917.1 - 0.15 12.2 7.3 0.23 11.6 7.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF3450 PF11932.8 CEP08917.1 - 0.34 10.2 6.6 0.46 9.8 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med9 PF07544.13 CEP08917.1 - 0.44 10.7 3.4 0.81 9.8 2.9 1.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-CpG_bind_C PF12269.8 CEP08917.1 - 0.46 10.2 3.3 0.7 9.6 3.3 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF4140 PF13600.6 CEP08917.1 - 0.65 10.5 4.5 1.2 9.6 4.5 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 CEP08917.1 - 4.6 7.5 7.5 3.8 7.8 6.1 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NCBP3 PF10309.9 CEP08918.1 - 0.0039 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CEP08918.1 - 0.0072 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Globin PF00042.22 CEP08919.1 - 6.4e-05 23.5 0.0 0.0083 16.7 0.0 2.5 2 1 0 2 2 2 2 Globin Alveol-reg_P311 PF11092.8 CEP08919.1 - 0.055 13.6 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Ras PF00071.22 CEP08920.1 - 3.1e-56 189.5 1.3 4.8e-56 188.8 1.3 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP08920.1 - 3.8e-31 107.8 0.1 1.1e-30 106.4 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP08920.1 - 1.5e-14 53.8 0.2 2.5e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cellulase PF00150.18 CEP08920.1 - 1.5e-10 41.0 0.0 4.7e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RsgA_GTPase PF03193.16 CEP08920.1 - 0.00094 19.1 1.7 0.75 9.7 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEP08920.1 - 0.011 15.2 0.4 0.018 14.5 0.4 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEP08920.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP08920.1 - 0.027 14.0 0.7 0.07 12.7 0.4 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP08920.1 - 0.054 12.8 0.9 0.087 12.2 0.9 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 CEP08920.1 - 0.085 13.4 0.6 0.45 11.0 0.2 2.4 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 CEP08920.1 - 0.12 12.1 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP08920.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3533 PF12051.8 CEP08920.1 - 0.18 10.7 2.9 0.28 10.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_5 PF07728.14 CEP08920.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sugar_tr PF00083.24 CEP08921.1 - 6.2e-92 308.8 25.2 7.4e-92 308.6 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP08921.1 - 2.2e-27 95.9 59.0 7.3e-26 90.9 26.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PTCB-BRCT PF12738.7 CEP08922.1 - 9.9e-30 102.3 0.0 9.4e-13 47.9 0.0 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CEP08922.1 - 2.4e-25 88.7 0.3 5e-07 30.0 0.0 4.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEP08922.1 - 6.1e-14 52.2 0.0 0.00047 20.5 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CEP08922.1 - 0.01 16.1 0.0 13 6.1 0.0 3.9 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain Cytochrom_C PF00034.21 CEP08923.1 - 2.6e-13 50.9 0.4 4.6e-13 50.1 0.1 1.6 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CEP08923.1 - 1.4e-07 31.8 3.3 9.2e-07 29.1 3.3 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CEP08923.1 - 0.015 15.0 0.2 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c-550 domain CCP_MauG PF03150.14 CEP08923.1 - 0.054 14.1 0.0 0.074 13.7 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase WD40 PF00400.32 CEP08924.1 - 1.2e-31 108.2 16.8 4.5e-07 30.5 1.3 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP08924.1 - 1.2e-13 51.2 4.9 0.0079 16.5 0.0 4.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP08924.1 - 1.5e-05 24.9 0.5 3 7.7 0.0 3.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A CLTH PF10607.9 CEP08924.1 - 0.00077 19.4 0.2 0.0012 18.7 0.2 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_like PF17005.5 CEP08924.1 - 0.001 18.4 0.1 0.0037 16.6 0.0 1.8 1 1 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 CEP08924.1 - 0.031 12.8 0.1 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain LSM PF01423.22 CEP08925.1 - 1.9e-16 59.5 1.1 2.3e-16 59.2 1.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CEP08925.1 - 0.0047 16.6 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Hfq protein GPI-anchored PF10342.9 CEP08926.1 - 4.1e-15 56.3 0.9 4.1e-15 56.3 0.9 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sec2p PF06428.11 CEP08927.1 - 1.1e-05 25.3 0.8 2.9e-05 23.9 0.8 1.8 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Marek_SORF3 PF07153.11 CEP08927.1 - 0.017 14.5 0.1 0.06 12.7 0.0 1.9 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein vATP-synt_E PF01991.18 CEP08928.1 - 1.6 8.1 12.8 3.4 7.0 12.8 1.5 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Asp-B-Hydro_N PF05279.11 CEP08928.1 - 1.6 8.7 8.9 1.8 8.6 8.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region G-patch PF01585.23 CEP08929.1 - 5.7e-16 58.1 1.1 1.5e-15 56.8 1.1 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 CEP08929.1 - 2.8e-11 43.2 0.0 6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.7 CEP08929.1 - 1e-06 28.7 0.0 1e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 G-patch domain zf-PARP PF00645.18 CEP08930.1 - 2.7e-13 50.6 0.9 2.7e-13 50.6 0.9 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kisspeptin PF15152.6 CEP08930.1 - 0.37 11.6 2.8 1.7 9.5 0.4 2.5 2 0 0 2 2 2 0 Kisspeptin DUF2052 PF09747.9 CEP08930.1 - 1.4 9.1 11.1 2.2 8.4 11.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) WGG PF10273.9 CEP08931.1 - 5.1e-28 97.6 0.2 9e-28 96.8 0.2 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TLP-20 PF06088.11 CEP08931.1 - 0.037 13.9 2.5 0.049 13.5 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Rep_fac-A_3 PF08661.11 CEP08932.1 - 3.3e-17 62.8 0.0 3.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 P5CR_dimer PF14748.6 CEP08933.1 - 6e-35 119.6 1.9 9.1e-35 119.0 1.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CEP08933.1 - 5.2e-18 65.4 0.0 1.5e-17 64.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CEP08933.1 - 0.0088 16.0 0.4 0.039 13.9 0.4 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Semialdhyde_dh PF01118.24 CEP08933.1 - 0.021 15.2 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Phosducin PF02114.16 CEP08934.1 - 5.2e-13 48.5 0.2 2.2e-12 46.5 0.2 1.8 1 1 0 1 1 1 1 Phosducin ECH_1 PF00378.20 CEP08935.1 - 7.1e-28 97.6 0.1 8.1e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP08935.1 - 6.3e-16 58.8 0.6 7.3e-16 58.6 0.6 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DDE_3 PF13358.6 CEP08936.1 - 8.3e-22 77.5 0.0 3.1e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF4246 PF14033.6 CEP08936.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF4820 PF16091.5 CEP08940.1 - 0.32 10.4 4.8 0.41 10.0 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) E3_binding PF02817.17 CEP08942.1 - 0.00033 20.9 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 e3 binding domain RRM_1 PF00076.22 CEP08943.1 - 1e-40 137.4 0.8 2.6e-17 62.4 0.3 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP08943.1 - 5.2e-09 36.2 0.0 5.2e-09 36.2 0.0 3.4 3 1 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 CEP08943.1 - 1.4e-06 28.3 0.8 0.29 11.2 0.0 4.3 4 0 0 4 4 4 2 Limkain b1 RRM_occluded PF16842.5 CEP08943.1 - 0.037 13.9 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRN9 PF10680.9 CEP08943.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Pkinase PF00069.25 CEP08944.1 - 1.3e-42 146.0 0.0 2.2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08944.1 - 3.1e-24 85.7 0.0 4.5e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 CEP08944.1 - 8.2e-16 58.1 0.4 8.2e-16 58.1 0.4 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 CEP08944.1 - 7e-06 25.1 0.0 1.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEP08944.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPBW PF15180.6 CEP08945.1 - 0.14 12.0 2.0 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Neuropeptides B and W Suf PF05843.14 CEP08945.1 - 4.9 7.0 11.4 0.47 10.4 3.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mito_carr PF00153.27 CEP08946.1 - 1.6e-44 149.8 5.2 8.2e-15 54.5 0.1 4.4 2 1 2 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.25 CEP08946.1 - 1.3e-42 146.0 0.0 2.1e-30 106.0 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP08946.1 - 4.8e-26 91.6 0.0 4.7e-25 88.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP08946.1 - 2.5e-08 33.1 0.2 5.5e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP08946.1 - 0.00082 19.4 0.2 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP08946.1 - 0.0094 15.3 0.0 0.05 12.9 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Ribosomal_L14 PF00238.19 CEP08947.1 - 3.1e-36 124.1 0.2 3.7e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Oxysterol_BP PF01237.18 CEP08948.1 - 2.1e-70 237.5 1.4 2.4e-68 230.7 1.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Sel1 PF08238.12 CEP08949.1 - 5.8e-102 331.8 95.2 2.1e-06 28.2 0.1 30.8 31 0 0 31 31 31 24 Sel1 repeat TPR_12 PF13424.6 CEP08949.1 - 0.0074 16.6 0.5 0.0074 16.6 0.5 10.4 11 2 1 12 12 12 2 Tetratricopeptide repeat DUF2796 PF10986.8 CEP08949.1 - 0.41 10.6 14.0 0.018 15.0 5.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2796) VHS PF00790.19 CEP08950.1 - 5.3e-20 71.7 2.8 1.7e-13 50.7 0.1 3.6 2 1 1 3 3 3 2 VHS domain FYVE PF01363.21 CEP08950.1 - 4.9e-18 65.0 8.8 9.4e-18 64.1 8.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger DUF202 PF02656.15 CEP08950.1 - 2e-07 31.4 0.1 3.8e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF202) UIM PF02809.20 CEP08950.1 - 2.8e-06 26.9 3.2 0.051 13.5 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif Hrs_helical PF12210.8 CEP08950.1 - 1.5e-05 25.5 0.2 1.5e-05 25.5 0.2 1.7 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.14 CEP08950.1 - 3.8e-05 23.9 1.1 0.00012 22.3 0.2 2.2 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 CEP08950.1 - 0.00027 21.2 3.2 0.0009 19.4 3.2 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger FSIP2 PF15783.5 CEP08950.1 - 0.024 12.6 0.1 0.034 12.1 0.1 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 DZR PF12773.7 CEP08950.1 - 0.08 13.0 10.0 1.4 9.0 3.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon Band_7 PF01145.25 CEP08951.1 - 1.9e-25 89.9 2.3 3.1e-25 89.2 2.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 CEP08951.1 - 0.082 13.0 0.4 0.3 11.2 0.4 1.9 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain MgtE_N PF03448.17 CEP08951.1 - 0.13 12.9 2.4 12 6.6 0.4 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain Bromodomain PF00439.25 CEP08952.1 - 1.5e-46 156.3 2.0 2.4e-23 82.0 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CEP08952.1 - 3.9e-22 78.2 0.2 1.5e-21 76.3 0.2 2.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 CEP08952.1 - 0.0053 16.7 9.3 0.0053 16.7 9.3 3.8 4 0 0 4 4 4 2 FlxA-like protein YL1 PF05764.13 CEP08952.1 - 0.0077 16.4 11.2 0.0077 16.4 11.2 3.1 3 0 0 3 3 3 1 YL1 nuclear protein DUF2802 PF10975.8 CEP08952.1 - 4.6 7.4 5.0 18 5.6 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF724 PF05266.14 CEP08952.1 - 8.7 6.1 13.1 11 5.8 8.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF724) EB1 PF03271.17 CEP08953.1 - 1.1e-16 60.7 0.8 2.7e-16 59.5 0.8 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CEP08953.1 - 3e-05 24.1 0.1 5.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 CEP08953.1 - 0.015 13.9 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-C4H2 PF10146.9 CEP08953.1 - 0.018 15.4 0.7 0.029 14.7 0.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Ustilago_mating PF05722.12 CEP08953.1 - 0.033 13.7 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Bromodomain PF00439.25 CEP08954.1 - 5e-18 65.0 0.9 1.4e-17 63.6 0.9 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CEP08954.1 - 2.9e-07 30.7 0.1 2.9e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP08954.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP08954.1 - 0.00036 20.9 0.1 0.00069 20.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain malic PF00390.19 CEP08954.1 - 0.061 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain RE_Eco47II PF09553.10 CEP08956.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Eco47II restriction endonuclease Rad51 PF08423.11 CEP08957.1 - 5.5e-40 137.2 0.5 1.6e-39 135.7 0.2 1.9 2 0 0 2 2 2 1 Rad51 HEAT PF02985.22 CEP08957.1 - 1.7e-08 34.0 15.3 0.0013 18.8 0.0 9.2 10 1 0 10 10 9 2 HEAT repeat HEAT_2 PF13646.6 CEP08957.1 - 2e-08 34.5 0.1 0.0053 17.1 0.0 5.7 5 1 2 7 7 6 2 HEAT repeats HEAT_EZ PF13513.6 CEP08957.1 - 7.8e-08 32.7 0.1 1.2e-05 25.7 0.0 4.6 7 0 0 7 7 5 1 HEAT-like repeat ATPase PF06745.13 CEP08957.1 - 2.2e-06 27.2 0.9 1.3e-05 24.7 0.9 2.2 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CEP08957.1 - 2.2e-06 27.4 0.0 4.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP08957.1 - 6.7e-06 26.4 0.0 2.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMS19_C PF12460.8 CEP08957.1 - 0.00017 20.9 0.2 0.00017 20.9 0.2 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal AAA_24 PF13479.6 CEP08957.1 - 0.002 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Vac14_Fab1_bd PF12755.7 CEP08957.1 - 0.0031 18.1 7.1 0.52 11.0 0.0 5.8 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region RecA PF00154.21 CEP08957.1 - 0.012 15.1 0.2 0.037 13.5 0.2 1.7 1 1 0 1 1 1 0 recA bacterial DNA recombination protein Cnd1 PF12717.7 CEP08957.1 - 0.014 15.4 5.8 0.035 14.2 0.9 3.7 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 PhoH PF02562.16 CEP08957.1 - 0.019 14.5 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Arm PF00514.23 CEP08957.1 - 0.083 13.0 0.1 0.083 13.0 0.1 3.6 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CEP08957.1 - 0.18 11.7 2.1 0.45 10.5 0.3 2.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain TRAP_alpha PF03896.16 CEP08958.1 - 6.2e-13 48.6 0.1 9.6e-13 48.0 0.1 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit FtsH_ext PF06480.15 CEP08958.1 - 0.0075 16.6 0.7 3.3 8.1 0.0 2.5 1 1 1 2 2 2 2 FtsH Extracellular DUF5305 PF17231.2 CEP08958.1 - 0.06 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Helitron_like_N PF14214.6 CEP08959.1 - 7.4e-19 68.7 0.0 1.3e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 CEP08959.1 - 0.075 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Inovirus Gp2 MukF_M PF17192.4 CEP08959.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 MukF middle domain PIF1 PF05970.14 CEP08961.1 - 2.3e-30 106.0 0.3 3.3e-21 75.9 0.0 2.4 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CEP08961.1 - 1.6e-23 83.9 0.2 6.3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CEP08961.1 - 1.8e-18 66.9 0.0 2.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP08961.1 - 1.8e-09 38.1 0.0 4.9e-09 36.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 CEP08961.1 - 3.5e-05 23.7 0.1 0.18 11.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CEP08961.1 - 0.006 14.6 0.0 0.019 12.9 0.0 1.7 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CEP08961.1 - 0.01 15.6 0.1 0.025 14.4 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CEP08961.1 - 0.028 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 CEP08961.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CEP08961.1 - 0.056 13.7 0.1 0.2 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP08961.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CEP08961.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Phage_GPA PF05840.13 CEP08961.1 - 0.25 10.4 1.4 1.7 7.7 1.4 2.0 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Sterol-sensing PF12349.8 CEP08965.1 - 0.49 10.2 5.4 0.75 9.6 5.4 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation MFS_Mycoplasma PF07672.13 CEP08965.1 - 0.96 8.7 4.6 1.8 7.7 4.6 1.5 1 1 0 1 1 1 0 Mycoplasma MFS transporter DPBB_1 PF03330.18 CEP08967.1 - 1.1e-12 48.0 0.1 1.9e-12 47.3 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP08967.1 - 0.0018 18.1 0.1 0.0026 17.6 0.1 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 CEP08968.1 - 5.5e-12 45.8 0.0 7.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP08968.1 - 0.0098 15.7 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 Barwin family Kinesin PF00225.23 CEP08969.1 - 1.5e-56 191.8 0.7 1.5e-56 191.8 0.7 3.1 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP08969.1 - 2.5e-06 27.5 1.7 6.4e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 Microtubule binding PKcGMP_CC PF16808.5 CEP08969.1 - 4.4e-05 23.3 5.7 0.22 11.4 0.1 3.9 3 0 0 3 3 3 3 Coiled-coil N-terminus of cGMP-dependent protein kinase PCRF PF03462.18 CEP08969.1 - 0.016 15.1 3.8 0.016 15.1 3.8 2.3 2 0 0 2 2 2 0 PCRF domain EXOSC1 PF10447.9 CEP08971.1 - 2.8e-16 60.1 2.9 1.9e-12 47.7 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CEP08971.1 - 2.3e-11 43.3 0.6 6.1e-11 41.9 0.3 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 CEP08971.1 - 0.011 16.1 1.0 0.089 13.2 1.0 2.3 1 1 0 1 1 1 0 S1 RNA binding domain PMP1_2 PF08114.11 CEP08972.1 - 0.12 12.1 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 ATPase proteolipid family RicinB_lectin_2 PF14200.6 CEP08973.1 - 1.3e-14 54.7 0.2 7.1e-06 26.7 0.0 2.6 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP08973.1 - 9.4e-10 38.8 0.0 5.4e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3759 PF12585.8 CEP08973.1 - 0.018 15.1 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) T3RM_EcoP15I_C PF18273.1 CEP08973.1 - 0.068 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain BSD PF03909.17 CEP08974.1 - 1.2e-11 44.5 0.7 2.5e-11 43.4 0.7 1.5 1 0 0 1 1 1 1 BSD domain FlxA PF14282.6 CEP08974.1 - 0.0076 16.2 0.1 0.0076 16.2 0.1 2.2 2 0 0 2 2 2 1 FlxA-like protein EP400_N PF15790.5 CEP08974.1 - 1.2 7.9 7.8 0.045 12.6 2.0 1.5 2 0 0 2 2 2 0 E1A-binding protein p400, N-terminal Rad17 PF03215.15 CEP08975.1 - 1.3e-23 83.9 0.1 7.6e-21 74.9 0.1 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CEP08975.1 - 4.3e-07 30.5 0.1 4.4e-06 27.2 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CEP08975.1 - 4.2e-06 27.2 0.0 9.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CEP08975.1 - 0.00013 21.8 1.3 0.00075 19.3 1.3 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CEP08975.1 - 0.00029 21.1 0.6 0.0029 17.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEP08975.1 - 0.00037 20.8 0.1 0.0053 17.1 0.1 2.8 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 CEP08975.1 - 0.00042 20.2 0.0 0.00093 19.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 CEP08975.1 - 0.001 19.6 0.4 0.0028 18.2 0.4 2.2 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 CEP08975.1 - 0.0013 18.0 0.1 0.0036 16.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 CEP08975.1 - 0.0033 17.7 0.0 0.0087 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_7 PF12775.7 CEP08975.1 - 0.0048 16.4 0.2 0.025 14.1 0.1 2.3 1 1 1 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CEP08975.1 - 0.0051 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 CEP08975.1 - 0.0056 16.5 0.1 0.034 13.9 0.0 2.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CEP08975.1 - 0.0057 16.6 0.1 0.2 11.6 0.1 2.4 2 0 0 2 2 2 1 NACHT domain NTPase_P4 PF11602.8 CEP08975.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 TsaE PF02367.17 CEP08975.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CEP08975.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CEP08975.1 - 0.022 14.8 0.1 0.061 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CEP08975.1 - 0.022 14.7 3.6 1.3 8.9 0.2 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CEP08975.1 - 0.023 14.8 0.1 0.066 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 CEP08975.1 - 0.024 14.4 0.3 0.051 13.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CEP08975.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CEP08975.1 - 0.089 12.2 0.3 0.32 10.4 0.1 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 CEP08975.1 - 0.091 11.9 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 CEP08975.1 - 0.094 12.8 1.7 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 CEP08975.1 - 8.8 6.8 7.9 37 4.7 5.2 2.6 2 1 0 2 2 2 0 AAA domain Glutaredoxin PF00462.24 CEP08976.1 - 3.4e-18 65.6 0.1 1.1e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 CEP08976.1 - 0.01 16.2 0.1 0.026 14.9 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CEP08976.1 - 0.025 15.0 0.2 0.062 13.8 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 CEP08976.1 - 0.088 12.6 1.3 0.44 10.3 0.7 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CEP08976.1 - 0.44 10.7 2.3 12 6.0 0.1 2.4 1 1 1 2 2 2 0 Thioredoxin VASt PF16016.5 CEP08977.1 - 1.3e-26 93.9 1.3 3.5e-26 92.5 1.3 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CEP08977.1 - 7.6e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain YlbD_coat PF14071.6 CEP08977.1 - 1.6 9.0 8.0 13 6.1 0.3 2.6 2 0 0 2 2 2 0 Putative coat protein Retrotrans_gag PF03732.17 CEP08978.1 - 9.5e-05 22.6 1.8 0.00016 21.9 0.2 2.2 1 1 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.24 CEP08979.1 - 1.6e-11 43.9 0.6 3.8e-11 42.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP08979.1 - 0.032 14.1 0.1 0.087 12.7 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Avidin PF01382.17 CEP08979.1 - 0.055 13.9 0.2 0.13 12.8 0.0 1.6 2 0 0 2 2 2 0 Avidin family Neuromodulin_N PF10580.9 CEP08979.1 - 0.65 9.9 4.5 1.2 9.1 0.4 2.5 2 0 0 2 2 2 0 Gap junction protein N-terminal region RVT_1 PF00078.27 CEP08980.1 - 8.7e-12 45.0 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAM2 PF07145.15 CEP08980.1 - 0.0057 16.3 0.9 0.0057 16.3 0.9 2.6 3 0 0 3 3 3 1 Ataxin-2 C-terminal region Aldedh PF00171.22 CEP08981.1 - 1.9e-67 227.8 0.1 2.1e-67 227.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP08981.1 - 0.033 13.7 0.1 0.046 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Nepo_coat_N PF03689.15 CEP08981.1 - 0.16 11.9 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain kleA_kleC PF17383.2 CEP08982.1 - 0.15 12.4 10.6 0.16 12.3 0.2 4.6 4 0 0 4 4 4 0 Uncharacterized KorC regulated protein A RCSD PF05177.12 CEP08982.1 - 1 10.3 5.2 3.5 8.6 5.2 1.9 1 0 0 1 1 1 0 RCSD region FlaC_arch PF05377.11 CEP08982.1 - 3.9 7.9 20.2 0.28 11.6 1.0 5.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DDE_3 PF13358.6 CEP08983.1 - 1.3e-25 89.9 0.1 4.9e-19 68.5 0.0 3.1 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_32 PF13565.6 CEP08983.1 - 5.5e-07 30.1 0.1 2.5e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP08983.1 - 3.9e-05 23.6 0.3 0.00031 20.7 0.2 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CEP08983.1 - 6.5e-05 22.6 1.0 0.0012 18.6 0.1 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CEP08983.1 - 0.00046 20.3 0.5 0.00046 20.3 0.5 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP08983.1 - 0.024 14.9 0.1 0.092 13.1 0.1 1.9 2 0 0 2 2 2 0 Transposase HTH_Tnp_ISL3 PF13542.6 CEP08983.1 - 0.051 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 CEP08983.1 - 0.084 13.1 1.5 1.5 9.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain MFS_1 PF07690.16 CEP08984.1 - 4.4e-21 75.2 22.2 5.4e-21 74.9 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box_2 PF09011.10 CEP08984.1 - 0.04 14.5 0.3 0.077 13.6 0.3 1.4 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 CEP08984.1 - 0.12 12.8 1.0 0.24 11.8 1.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box CbtA_toxin PF06755.12 CEP08985.1 - 0.15 12.1 0.1 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system RVT_1 PF00078.27 CEP08986.1 - 4.9e-18 65.5 0.0 7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CENP-R PF06729.12 CEP08986.1 - 0.084 12.8 2.5 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Kinetochore component, CENP-R Tropomyosin_1 PF12718.7 CEP08988.1 - 0.024 14.8 0.9 0.05 13.8 0.9 1.5 1 0 0 1 1 1 0 Tropomyosin like CHDCT2 PF08074.11 CEP08988.1 - 0.16 12.1 0.6 0.42 10.8 0.6 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Fib_alpha PF08702.10 CEP08988.1 - 0.36 11.0 3.4 0.89 9.7 3.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cor1 PF04803.12 CEP08988.1 - 0.97 9.6 3.9 1.7 8.9 3.9 1.3 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region SKA2 PF16740.5 CEP08988.1 - 1.3 8.8 6.4 8.8 6.2 1.5 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4603 PF15376.6 CEP08989.1 - 0.28 8.5 4.3 0.3 8.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MGC-24 PF05283.11 CEP08989.1 - 2.7 8.5 8.0 3.8 8.0 8.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-CCHC PF00098.23 CEP08990.1 - 0.0015 18.5 4.5 0.0015 18.5 4.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 CEP08990.1 - 0.09 12.5 4.2 0.4 10.4 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 CEP08991.1 - 2.3e-37 128.7 0.0 2.4e-36 125.4 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) HR1 PF02185.16 CEP08991.1 - 0.055 13.6 2.0 0.19 11.9 2.0 1.9 1 0 0 1 1 1 0 Hr1 repeat Ribosomal_L41 PF05162.13 CEP08991.1 - 1.7 8.8 7.6 3.7 7.7 7.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L41 RVT_1 PF00078.27 CEP08992.1 - 6.7e-07 29.1 0.1 9.5e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP08993.1 - 2.9e-17 62.9 0.0 5.9e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP08993.1 - 8.2e-05 22.4 0.5 0.00035 20.4 0.5 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP08993.1 - 0.00038 20.0 0.0 0.00098 18.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.6 CEP08993.1 - 0.19 11.5 6.7 9.7 6.0 4.7 2.6 2 0 0 2 2 2 0 Zinc knuckle BRO1 PF03097.18 CEP08994.1 - 1.3e-93 314.0 1.4 1.3e-93 314.0 1.4 2.3 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEP08994.1 - 2.3e-77 260.2 16.5 3.9e-77 259.5 16.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Adeno_Penton_B PF01686.17 CEP08994.1 - 0.017 13.6 0.0 0.032 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus penton base protein DUF5595 PF18077.1 CEP08994.1 - 0.018 15.1 5.4 0.27 11.3 2.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) 3H PF02829.14 CEP08994.1 - 0.096 13.0 0.4 0.35 11.2 0.4 1.9 1 0 0 1 1 1 0 3H domain JIP_LZII PF16471.5 CEP08994.1 - 1.3 9.2 5.2 28 5.0 0.2 3.7 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II RVT_1 PF00078.27 CEP08995.1 - 8.5e-13 48.3 0.2 4.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CEP08997.1 - 0.00016 21.5 0.3 0.00028 20.7 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos PF03372.23 CEP08998.1 - 4.2e-08 33.0 0.1 1e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 CEP08998.1 - 7.3e-08 32.2 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP08998.1 - 2.2e-06 27.5 5.5 6.7e-06 25.9 0.6 2.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Acetyltransf_17 PF17668.1 CEP08998.1 - 0.16 12.8 0.2 3.3 8.6 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 CEP09000.1 - 2.9e-26 92.4 0.0 3.8e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP09000.1 - 1.2e-05 25.7 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP09000.1 - 7.6e-05 22.1 0.1 0.0034 16.7 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.19 CEP09000.1 - 0.14 11.5 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 CEP09000.1 - 0.22 10.5 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 CEP09001.1 - 2.5e-17 62.9 48.1 7.2e-15 54.8 47.5 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3700 PF12481.8 CEP09002.1 - 0.058 12.8 0.0 0.062 12.8 0.0 1.0 1 0 0 1 1 1 0 Aluminium induced protein Cation_efflux PF01545.21 CEP09003.1 - 8e-52 175.9 5.8 1e-51 175.6 5.8 1.1 1 0 0 1 1 1 1 Cation efflux family Sterol-sensing PF12349.8 CEP09004.1 - 6.1e-22 78.1 3.7 1.3e-21 77.1 3.7 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Arrestin_C PF02752.22 CEP09004.1 - 8.4e-19 68.4 0.0 8.1e-16 58.7 0.0 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP09004.1 - 1.2e-16 61.0 0.0 3.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Patched PF02460.18 CEP09004.1 - 1.1e-09 37.0 3.5 1.7e-09 36.4 3.5 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CEP09004.1 - 1e-06 29.4 6.3 1.7 9.6 0.1 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 CEP09004.1 - 4.4e-06 25.6 5.7 0.00078 18.2 0.1 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 LDB19 PF13002.7 CEP09004.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like W_rich_C PF07483.11 CEP09004.1 - 0.067 13.3 0.4 2.3 8.4 0.1 3.2 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Comm PF15957.5 CEP09004.1 - 0.23 11.8 1.3 14 6.1 0.0 3.5 3 0 0 3 3 3 0 Commissureless Orf78 PF06024.12 CEP09005.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DUF981 PF06168.11 CEP09005.1 - 0.062 13.2 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) WD40 PF00400.32 CEP09006.1 - 2.5e-19 69.3 6.5 0.00022 21.9 0.0 6.1 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09006.1 - 5.5e-08 33.0 0.0 0.19 12.1 0.0 4.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP09006.1 - 1.6e-07 31.0 0.0 1.7e-06 27.6 0.0 1.9 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.11 CEP09006.1 - 2.1e-05 24.5 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 CEP09006.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 TUP1-like enhancer of split PQQ_3 PF13570.6 CEP09006.1 - 1.6 9.3 4.6 1.6 9.3 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Hydrolase_4 PF12146.8 CEP09007.1 - 1.1e-20 73.9 0.0 4.7e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP09007.1 - 8.1e-14 51.9 0.0 2.6e-11 43.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP09007.1 - 2.8e-13 51.0 0.0 3.6e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CEP09007.1 - 5.9e-08 32.5 0.0 9.3e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CEP09007.1 - 0.00012 21.7 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 CEP09007.1 - 0.00027 20.7 0.0 0.3 10.8 0.0 2.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family DUF2920 PF11144.8 CEP09007.1 - 0.00044 19.5 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Chlorophyllase2 PF12740.7 CEP09007.1 - 0.002 17.1 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Esterase PF00756.20 CEP09007.1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.11 CEP09007.1 - 0.05 12.6 0.0 0.73 8.8 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Lipase_3 PF01764.25 CEP09007.1 - 0.053 13.4 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 CEP09007.1 - 0.083 12.2 0.1 0.4 10.0 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 CEP09007.1 - 0.14 12.3 0.0 0.89 9.6 0.0 2.0 1 1 0 1 1 1 0 Thioesterase domain YtxH PF12732.7 CEP09007.1 - 0.39 11.3 2.6 0.9 10.1 0.2 2.2 1 1 1 2 2 2 0 YtxH-like protein EamA PF00892.20 CEP09008.1 - 5.2e-05 23.4 11.8 0.0017 18.5 11.8 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 CEP09008.1 - 0.00018 21.5 1.5 0.00021 21.3 1.5 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 UAA PF08449.11 CEP09008.1 - 0.00077 18.8 4.2 0.0009 18.5 4.2 1.1 1 0 0 1 1 1 1 UAA transporter family Nup54 PF13874.6 CEP09009.1 - 6.1e-33 113.9 10.8 9.8e-33 113.2 10.8 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Phage_TAC_3 PF06896.11 CEP09009.1 - 0.096 13.3 0.6 0.18 12.4 0.1 1.6 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC LOH1CR12 PF10158.9 CEP09009.1 - 0.22 11.5 2.5 0.4 10.7 2.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Nucleoporin_FG PF13634.6 CEP09009.1 - 0.99 10.3 112.9 42 5.1 38.9 4.2 1 1 3 4 4 4 0 Nucleoporin FG repeat region Nup54_C PF18437.1 CEP09009.1 - 2.9 7.9 6.8 0.19 11.6 0.4 2.1 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Polysacc_deac_1 PF01522.21 CEP09010.1 - 5.1e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase FA_hydroxylase PF04116.13 CEP09011.1 - 5.5e-23 81.8 24.6 5.5e-23 81.8 24.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MoaF_C PF17409.2 CEP09011.1 - 0.94 9.2 4.0 2.5 7.8 0.0 2.7 2 1 1 3 3 3 0 MoaF C-terminal domain MOSC_N PF03476.16 CEP09012.1 - 1.1e-22 80.2 0.0 1.7e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 CEP09012.1 - 2.9e-19 69.4 0.0 5.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain DUF3908 PF13048.6 CEP09012.1 - 0.019 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) MMS19_N PF14500.6 CEP09013.1 - 9.7e-77 258.1 2.8 1.1e-74 251.3 0.1 3.5 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CEP09013.1 - 3.6e-72 243.8 23.0 4.8e-54 184.1 10.1 5.2 4 1 0 4 4 4 3 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CEP09013.1 - 2.3e-05 24.8 0.9 0.0042 17.6 0.1 3.8 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 CEP09013.1 - 6.2e-05 23.3 3.8 0.04 14.3 0.1 4.7 4 0 0 4 4 3 1 HEAT repeats TMEM101 PF15111.6 CEP09013.1 - 0.0025 17.4 0.1 0.0063 16.1 0.1 1.6 1 0 0 1 1 1 1 TMEM101 protein family ERAP1_C PF11838.8 CEP09013.1 - 0.0036 16.9 0.4 0.017 14.7 0.0 2.3 3 0 0 3 3 3 1 ERAP1-like C-terminal domain ParcG PF10274.9 CEP09013.1 - 0.038 14.1 0.6 0.038 14.1 0.6 2.6 3 0 0 3 3 3 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 CEP09013.1 - 0.04 14.5 0.5 0.92 10.1 0.0 3.5 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region DUF3819 PF12842.7 CEP09013.1 - 0.049 13.6 0.4 0.21 11.5 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) TetR_C_20 PF17925.1 CEP09013.1 - 0.065 13.6 0.7 0.8 10.0 0.1 3.2 2 1 1 3 3 2 0 Tetracyclin repressor-like, C-terminal domain MukF_M PF17192.4 CEP09013.1 - 0.067 12.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 MukF middle domain SIL1 PF16782.5 CEP09013.1 - 0.068 12.4 4.3 4.2 6.5 0.1 3.5 3 1 1 4 4 4 0 Nucleotide exchange factor SIL1 Telomere_reg-2 PF10193.9 CEP09013.1 - 0.083 13.3 3.4 0.64 10.5 0.1 3.8 3 1 1 4 4 4 0 Telomere length regulation protein HEAT PF02985.22 CEP09013.1 - 0.1 12.9 4.2 62 4.3 0.1 5.4 5 0 0 5 5 4 0 HEAT repeat Xylo_C PF12529.8 CEP09014.1 - 0.0083 15.8 1.6 0.013 15.1 0.4 1.8 2 0 0 2 2 2 1 Xylosyltransferase C terminal Med3 PF11593.8 CEP09014.1 - 0.44 9.7 4.1 0.82 8.8 4.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SH3_9 PF14604.6 CEP09015.1 - 1.6e-30 104.7 0.1 6.8e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CEP09015.1 - 5.3e-28 96.4 0.4 4.4e-17 61.4 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CEP09015.1 - 3.6e-21 74.6 0.0 1.4e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 CEP09015.1 - 4.7e-19 68.5 1.6 4.7e-19 68.5 1.6 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 CEP09015.1 - 7.9e-13 48.1 7.8 1.3e-12 47.4 7.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5082 PF16888.5 CEP09015.1 - 0.0036 17.6 0.3 0.0036 17.6 0.3 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF5082) SH3_10 PF17902.1 CEP09015.1 - 0.019 15.0 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 SH3 domain C1_2 PF03107.16 CEP09015.1 - 0.048 14.0 4.7 0.09 13.1 4.7 1.4 1 0 0 1 1 1 0 C1 domain CotJB PF12652.7 CEP09015.1 - 0.076 13.3 1.4 0.48 10.7 0.2 2.5 2 0 0 2 2 2 0 CotJB protein FYVE PF01363.21 CEP09015.1 - 0.079 13.1 3.1 0.17 12.0 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger NusB PF01029.18 CEP09015.1 - 0.19 12.0 2.8 0.2 11.9 0.7 2.1 2 0 0 2 2 2 0 NusB family Zf_RING PF16744.5 CEP09015.1 - 0.51 10.5 4.0 1 9.5 3.1 1.9 2 0 0 2 2 1 0 KIAA1045 RING finger Golgin_A5 PF09787.9 CEP09015.1 - 0.53 9.7 9.9 0.53 9.7 0.4 2.5 2 1 0 2 2 2 0 Golgin subfamily A member 5 HrpB7 PF09486.10 CEP09015.1 - 1.3 9.4 5.2 4.3 7.7 0.6 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) RICH PF05062.12 CEP09015.1 - 2.1 8.7 10.2 1.1 9.7 0.3 3.5 4 0 0 4 4 4 0 RICH domain PHD PF00628.29 CEP09015.1 - 3.3 7.7 7.4 7.4 6.6 7.4 1.6 1 0 0 1 1 1 0 PHD-finger DUF4200 PF13863.6 CEP09015.1 - 3.3 8.1 12.9 1.6 9.2 1.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) Retrotrans_gag PF03732.17 CEP09016.1 - 0.00027 21.1 0.0 0.00045 20.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP09016.1 - 0.00033 20.5 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Hydrolase_6 PF13344.6 CEP09016.1 - 0.036 14.2 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PIF1 PF05970.14 CEP09018.1 - 4e-22 78.9 0.1 5.5e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP09018.1 - 3.4e-07 28.6 0.0 4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP09018.1 - 1.9e-05 24.4 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Retrotrans_gag PF03732.17 CEP09021.1 - 0.0004 20.6 0.0 0.0023 18.2 0.0 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CEP09021.1 - 0.038 14.1 3.8 0.07 13.2 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 CEP09022.1 - 4.3e-09 36.3 0.2 6.4e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP09022.1 - 4.2e-06 27.0 0.0 9.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP09022.1 - 0.00081 19.6 0.9 0.0014 18.8 0.9 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Helitron_like_N PF14214.6 CEP09023.1 - 6.8e-40 137.3 0.6 3.8e-28 99.0 0.0 2.3 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus MHC_II_alpha PF00993.20 CEP09023.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain CFIA_Pcf11 PF11526.8 CEP09024.1 - 0.01 16.3 0.0 0.036 14.5 0.0 2.0 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 DNA_RNApol_7kD PF03604.13 CEP09024.1 - 0.015 15.0 0.1 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit RNF220 PF15926.5 CEP09025.1 - 4e-38 131.5 8.4 8e-38 130.5 8.4 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 CEP09025.1 - 2.5e-11 43.2 19.6 3.2e-11 42.9 12.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP09025.1 - 6e-05 22.8 16.8 0.00044 20.0 8.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP09025.1 - 6.5e-05 22.7 14.5 0.024 14.5 8.5 3.4 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEP09025.1 - 0.0017 18.2 11.7 0.0017 18.2 11.7 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP09025.1 - 0.0032 17.8 12.3 0.0032 17.8 12.3 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CEP09025.1 - 0.0073 16.2 10.0 0.0073 16.2 10.0 3.2 3 0 0 3 3 3 1 zinc-RING finger domain LMWPc PF01451.21 CEP09025.1 - 0.073 13.5 0.2 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase zf-ANAPC11 PF12861.7 CEP09025.1 - 0.92 9.6 10.2 0.28 11.3 6.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 CEP09025.1 - 7.6 6.4 10.4 0.46 10.3 4.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RAP80_UIM PF18282.1 CEP09026.1 - 0.02 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif DUF5320 PF17253.2 CEP09026.1 - 0.11 13.6 0.4 0.23 12.5 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DDT PF02791.17 CEP09029.1 - 0.045 14.1 0.7 1.4 9.3 0.7 2.3 1 1 0 1 1 1 0 DDT domain RVT_1 PF00078.27 CEP09029.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP09032.1 - 4.3e-37 126.2 0.0 1e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP09032.1 - 3e-36 123.9 0.0 8.4e-36 122.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP09032.1 - 1.6e-20 72.9 0.0 3.1e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP09032.1 - 1.3e-19 70.6 0.0 5.1e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CEP09032.1 - 8.1e-11 41.9 0.0 2.4e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CEP09032.1 - 0.00026 20.7 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Exo_endo_phos PF03372.23 CEP09033.1 - 0.0073 15.8 0.0 0.021 14.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CotH PF08757.11 CEP09035.1 - 9.2e-35 120.7 6.6 1.4e-34 120.1 6.6 1.3 1 0 0 1 1 1 1 CotH kinase protein DUF1752 PF08550.10 CEP09036.1 - 3.1e-14 52.5 0.8 7.8e-14 51.2 0.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GCR1_C PF12550.8 CEP09037.1 - 1.1e-15 57.6 0.4 2.3e-15 56.6 0.4 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes RRS1 PF04939.12 CEP09037.1 - 0.03 14.2 0.2 0.03 14.2 0.2 1.7 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) GLYCAM-1 PF05242.11 CEP09037.1 - 0.078 13.1 2.3 1.1 9.4 0.1 2.4 2 1 1 3 3 3 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) NDC10_II PF16787.5 CEP09038.1 - 3.8e-22 78.8 0.0 4.4e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CTP_transf_1 PF01148.20 CEP09039.1 - 1.2e-68 231.7 22.4 1.8e-68 231.2 22.4 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Gemini_coat PF00844.18 CEP09039.1 - 0.08 12.4 0.4 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family CPSase_L_D2 PF02786.17 CEP09041.1 - 3.5e-107 356.7 0.0 1.5e-82 276.2 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CEP09041.1 - 4.8e-37 127.0 0.2 7.1e-36 123.2 0.0 2.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CEP09041.1 - 6.6e-14 51.8 0.0 2.5e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CEP09041.1 - 1.8e-12 47.3 0.1 2.2e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CEP09041.1 - 3e-10 39.9 0.0 0.00012 21.9 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 CEP09041.1 - 6.7e-06 25.7 0.0 0.0011 18.4 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CEP09041.1 - 6e-05 22.7 0.0 0.078 12.6 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain TrkA_N PF02254.18 CEP09041.1 - 0.015 15.5 0.1 0.65 10.3 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain Synaptobrevin PF00957.21 CEP09043.1 - 4.3e-15 55.3 0.2 7.5e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEP09043.1 - 6.7e-10 38.9 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain REC1 PF18501.1 CEP09043.1 - 0.024 14.5 0.6 0.031 14.2 0.6 1.1 1 0 0 1 1 1 0 Alpha helical recognition lobe domain Syntaxin-6_N PF09177.11 CEP09043.1 - 0.085 13.4 0.3 0.14 12.7 0.3 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Phytochelatin PF05023.14 CEP09044.1 - 5.1e-85 284.0 0.0 7.5e-85 283.5 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 CEP09044.1 - 0.015 15.8 0.0 0.062 13.9 0.0 2.0 1 1 0 1 1 1 0 Peptidase_C39 like family Peptidase_C14 PF00656.22 CEP09045.1 - 4.5e-49 167.7 0.0 1.1e-48 166.4 0.0 1.7 1 0 0 1 1 1 1 Caspase domain Fungal_trans PF04082.18 CEP09045.1 - 1.1e-16 60.7 0.1 1.6e-13 50.3 0.0 2.8 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF3730 PF12530.8 CEP09045.1 - 0.052 13.1 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) DUF3446 PF11928.8 CEP09045.1 - 8.2 6.8 14.1 36 4.8 12.7 2.8 2 1 0 2 2 2 0 Early growth response N-terminal domain ADH_N_2 PF16884.5 CEP09046.1 - 3e-22 78.6 0.0 5.6e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CEP09046.1 - 2.1e-21 76.2 0.0 3.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP09046.1 - 0.0098 16.9 0.0 0.034 15.2 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L2 PF00181.23 CEP09046.1 - 0.11 12.5 0.0 4.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Ribosomal Proteins L2, RNA binding domain CAP_N PF01213.19 CEP09047.1 - 1e-111 373.5 2.1 1e-111 373.5 2.1 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CEP09047.1 - 5.9e-62 207.9 8.5 8.5e-62 207.4 8.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CEP09047.1 - 0.0011 18.6 4.4 0.0041 16.8 4.1 1.9 1 1 0 1 1 1 1 Tubulin binding cofactor C PAR1 PF06521.11 CEP09047.1 - 0.0038 16.9 0.6 0.0085 15.7 0.6 1.6 1 0 0 1 1 1 1 PAR1 protein PRIMA1 PF16101.5 CEP09047.1 - 3.1 7.9 16.2 27 4.8 12.0 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Aldedh PF00171.22 CEP09048.1 - 1.5e-75 254.5 0.0 1.8e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Anp1 PF03452.14 CEP09049.1 - 7.8e-92 307.4 0.1 9.3e-92 307.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CEP09049.1 - 6.3e-06 26.1 0.2 0.00027 20.8 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAR1 PF03101.15 CEP09050.1 - 1.9e-08 34.9 1.4 3.6e-08 34.0 1.4 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4817 PF16087.5 CEP09050.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) zinc_ribbon_6 PF14599.6 CEP09051.1 - 0.073 13.1 3.4 2.7 8.1 1.4 3.3 2 1 0 2 2 2 0 Zinc-ribbon zf-Dof PF02701.15 CEP09051.1 - 0.099 12.8 1.7 0.38 10.9 0.7 2.4 2 0 0 2 2 2 0 Dof domain, zinc finger C1_4 PF07975.12 CEP09051.1 - 0.24 11.7 4.9 9.8 6.5 1.5 3.2 2 1 0 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 CEP09051.1 - 1.8 8.6 7.4 0.89 9.6 1.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 CEP09051.1 - 6.2 6.7 7.4 2.1 8.2 0.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type AAA_11 PF13086.6 CEP09052.1 - 8.3e-09 35.6 2.5 0.0026 17.6 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 CEP09052.1 - 1.5e-06 28.6 0.0 4.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP09052.1 - 1.8e-06 27.8 0.0 8.2e-05 22.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CEP09052.1 - 0.00066 19.4 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 CEP09052.1 - 0.0012 19.0 0.4 0.024 14.7 0.0 2.8 1 1 0 2 2 2 1 Domain of unknown function DUF83 DUF1768 PF08719.11 CEP09052.1 - 0.066 13.5 0.6 0.15 12.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) AAA_22 PF13401.6 CEP09052.1 - 0.11 12.8 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Complex1_49kDa PF00346.19 CEP09054.1 - 0.047 12.8 0.5 0.11 11.6 0.5 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit GreA_GreB_N PF03449.15 CEP09054.1 - 0.064 13.4 7.4 1 9.5 0.3 2.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal AFP_2 PF18815.1 CEP09054.1 - 0.088 13.1 0.0 6.8 7.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Methyltransf_22 PF13383.6 CEP09054.1 - 0.094 12.3 0.5 0.18 11.3 0.4 1.5 1 1 0 1 1 1 0 Methyltransferase domain NBP1 PF08537.10 CEP09054.1 - 0.72 9.2 8.8 1.5 8.1 8.5 1.6 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 CdvA PF18822.1 CEP09054.1 - 0.79 9.6 8.8 4.6 7.1 6.1 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Exo_endo_phos PF03372.23 CEP09056.1 - 1.4e-08 34.5 0.1 4.2e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP09056.1 - 0.00034 20.5 0.0 0.00079 19.3 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Tetrabrachion PF11401.8 CEP09057.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetrabrachion RVT_1 PF00078.27 CEP09058.1 - 3.8e-15 56.0 0.0 4.3e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DMAP1_like PF17024.5 CEP09061.1 - 0.046 13.8 0.3 0.083 13.0 0.3 1.4 1 0 0 1 1 1 0 Putative DMAP1-like Chromo PF00385.24 CEP09062.1 - 9e-08 31.9 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Amidase_6 PF12671.7 CEP09062.1 - 0.06 13.5 1.0 0.13 12.4 0.6 1.6 1 1 0 2 2 2 0 Putative amidase domain Fox-1_C PF12414.8 CEP09063.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Neisseria_TspB PF05616.13 CEP09064.1 - 0.63 8.5 5.7 0.68 8.3 5.7 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Viral_NABP PF05515.11 CEP09066.1 - 0.084 12.7 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Viral nucleic acid binding RVT_1 PF00078.27 CEP09068.1 - 1e-25 90.5 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP09068.1 - 7.4e-10 38.8 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sec66 PF09802.9 CEP09068.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 PAS_11 PF14598.6 CEP09068.1 - 0.029 14.5 0.0 0.68 10.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain DUF677 PF05055.12 CEP09068.1 - 0.4 9.5 1.2 0.44 9.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Phage_integrase PF00589.22 CEP09069.1 - 0.034 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family ErmC PF06308.11 CEP09069.1 - 0.037 14.4 0.1 0.064 13.6 0.1 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) Cas1_AcylT PF07779.12 CEP09070.1 - 2.1e-136 455.6 30.3 3.2e-136 455.0 30.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 CEP09070.1 - 3.4e-06 27.0 0.0 6.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sec10 PF07393.11 CEP09071.1 - 2.1e-182 608.2 5.6 3.4e-182 607.6 5.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 CEP63 PF17045.5 CEP09071.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.2 3 0 0 3 3 3 0 Centrosomal protein of 63 kDa Syntaxin-6_N PF09177.11 CEP09071.1 - 0.023 15.3 2.1 0.088 13.4 0.3 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal MLD PF11647.8 CEP09071.1 - 0.059 13.7 0.0 4.4 7.7 0.0 2.9 2 0 0 2 2 2 0 Membrane Localization Domain GIT1_C PF12205.8 CEP09071.1 - 0.083 13.0 1.9 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term TFIIA PF03153.13 CEP09071.1 - 0.2 11.6 9.8 0.39 10.7 9.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CEP09071.1 - 3.4 8.3 11.0 8.8 7.0 11.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CEP09071.1 - 3.8 7.1 13.7 8.3 5.9 13.7 1.5 1 0 0 1 1 1 0 Spt20 family Indigoidine_A PF04227.12 CEP09072.1 - 0.048 13.0 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Indigoidine synthase A like protein DTHCT PF08070.11 CEP09072.1 - 0.36 11.6 3.7 0.17 12.6 0.6 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region Ferrochelatase PF00762.19 CEP09073.1 - 2.9e-112 374.8 0.0 3.5e-112 374.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CEP09073.1 - 0.0056 17.0 0.0 5.4 7.4 0.0 3.4 3 0 0 3 3 3 1 CbiX Peptidase_M24 PF00557.24 CEP09074.1 - 3.5e-41 141.2 0.0 6e-41 140.4 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 UPF0560 PF10577.9 CEP09074.1 - 0.57 8.6 3.3 0.76 8.2 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3391 PF11871.8 CEP09074.1 - 2.3 8.8 13.4 7.3 7.1 13.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) TMEM214 PF10151.9 CEP09074.1 - 5.2 5.4 6.2 7.2 4.9 6.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator PIEZO PF15917.5 CEP09074.1 - 8.3 5.8 6.7 12 5.3 6.7 1.1 1 0 0 1 1 1 0 Piezo mRNA_cap_enzyme PF01331.19 CEP09075.1 - 3.6e-47 160.7 0.1 7.1e-47 159.8 0.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CEP09075.1 - 2.5e-30 105.3 0.0 4.6e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CEP09075.1 - 2.6e-09 37.0 0.4 1.2e-05 25.0 0.1 2.9 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CEP09075.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA ligase Nucleoporin2 PF04096.14 CEP09076.1 - 1.1e-44 152.2 0.0 1.7e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CEP09076.1 - 0.00055 20.7 43.7 0.00055 20.7 43.7 10.0 3 2 4 7 7 7 2 Nucleoporin FG repeat region zf-RVT PF13966.6 CEP09077.1 - 9.1e-06 26.3 0.4 9.1e-06 26.3 0.4 1.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF2256 PF10013.9 CEP09077.1 - 0.046 13.9 0.4 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) HTH_Tnp_1_2 PF13022.6 CEP09078.1 - 0.073 13.2 0.4 0.15 12.2 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Nop14 PF04147.12 CEP09079.1 - 0.00023 19.6 19.1 0.00026 19.4 19.1 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CEP09079.1 - 0.00037 20.0 19.0 0.00042 19.8 19.0 1.1 1 0 0 1 1 1 1 SDA1 DUF2457 PF10446.9 CEP09079.1 - 0.00094 18.4 28.1 0.0013 18.0 28.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Mpp10 PF04006.12 CEP09079.1 - 0.001 17.6 13.9 0.0012 17.4 13.9 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 CEP09079.1 - 0.0043 15.4 15.3 0.0054 15.1 15.3 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 CEP09079.1 - 0.0057 16.1 14.9 0.0065 15.9 14.9 1.1 1 0 0 1 1 1 1 BUD22 BSP_II PF05432.11 CEP09079.1 - 0.079 12.6 21.9 0.11 12.1 21.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SpoIIP PF07454.11 CEP09079.1 - 0.13 11.6 5.1 0.19 11.2 5.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 CEP09079.1 - 0.24 11.4 20.4 0.27 11.2 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pes-10 PF07149.11 CEP09079.1 - 0.27 10.2 13.8 0.41 9.6 13.8 1.3 1 0 0 1 1 1 0 Pes-10 PPP4R2 PF09184.11 CEP09079.1 - 0.43 10.1 20.2 0.63 9.6 20.2 1.3 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 CEP09079.1 - 0.46 9.8 11.6 0.65 9.3 11.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 CEP09079.1 - 0.56 8.9 5.8 0.55 8.9 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 CEP09079.1 - 0.73 8.5 7.6 1 8.1 7.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 CEP09079.1 - 0.94 9.8 9.2 1.7 8.9 9.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 CEP09079.1 - 0.96 7.5 36.1 1.3 7.0 36.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 CEP09079.1 - 1.3 7.5 17.3 1.6 7.1 17.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RPN2_C PF18004.1 CEP09079.1 - 5.5 6.9 7.9 12 5.8 7.9 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Herpes_LMP1 PF05297.11 CEP09079.1 - 6.4 5.9 15.6 7.7 5.6 15.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CobT PF06213.12 CEP09079.1 - 8.1 5.7 26.3 13 5.1 26.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Med27 PF11571.8 CEP09081.1 - 5.4e-16 58.7 1.0 1.3e-15 57.5 0.5 2.0 2 0 0 2 2 2 1 Mediator complex subunit 27 DUF5446 PF17522.2 CEP09081.1 - 7 6.9 7.6 44 4.4 2.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5446) HECT_2 PF09814.9 CEP09082.1 - 4.1e-46 157.5 4.7 5e-46 157.3 4.7 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_4 PF13717.6 CEP09082.1 - 0.034 14.1 1.8 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 CEP09082.1 - 0.092 12.8 1.2 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ogr_Delta PF04606.12 CEP09082.1 - 0.51 10.4 2.3 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 CEP09082.1 - 2.3 7.7 5.3 18 4.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain F-box-like PF12937.7 CEP09083.1 - 0.00052 19.8 0.8 0.0014 18.5 0.8 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CEP09083.1 - 0.0021 18.4 12.4 0.35 11.4 0.3 5.2 2 2 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP09083.1 - 0.01 15.8 7.7 8.3 6.8 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CEP09083.1 - 0.71 10.6 9.0 23 6.0 0.2 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat Ytp1 PF10355.9 CEP09084.1 - 1e-51 175.8 17.2 1.7e-27 96.3 10.0 2.8 1 1 1 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CEP09084.1 - 6.8e-25 86.9 5.7 6.8e-25 86.9 5.7 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 CEP09084.1 - 2.3e-05 24.6 8.5 2.3e-05 24.6 8.5 3.3 3 1 0 3 3 3 2 Eukaryotic cytochrome b561 DUF1201 PF06716.11 CEP09084.1 - 8.9 6.4 8.6 1.8 8.6 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Kelch_3 PF13415.6 CEP09085.1 - 7.2e-08 32.5 14.7 0.0013 18.9 1.4 5.0 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CEP09085.1 - 2.7e-06 27.3 10.3 0.00022 21.2 0.9 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP09085.1 - 1.4e-05 25.2 16.5 6e-05 23.2 0.2 5.2 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CEP09085.1 - 1.7e-05 24.6 1.0 0.62 10.1 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CEP09085.1 - 0.00037 20.4 10.1 5.1 7.2 0.0 5.9 6 0 0 6 6 6 1 Kelch motif VSP PF03302.13 CEP09085.1 - 0.0087 15.0 0.3 0.013 14.4 0.3 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR2 PF02439.15 CEP09085.1 - 0.034 13.9 0.5 0.034 13.9 0.5 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MBA1 PF07961.11 CEP09085.1 - 0.038 13.0 0.1 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 MBA1-like protein Kelch_1 PF01344.25 CEP09085.1 - 0.16 11.5 0.1 0.16 11.5 0.1 4.4 5 1 0 5 5 5 0 Kelch motif Gram_pos_anchor PF00746.21 CEP09085.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 LPXTG cell wall anchor motif HTH_28 PF13518.6 CEP09087.1 - 0.0038 17.3 1.1 0.0083 16.2 1.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CEP09087.1 - 0.0093 15.4 0.0 0.035 13.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 FeoC PF09012.10 CEP09087.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_29 PF13551.6 CEP09087.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 CEP09087.1 - 0.085 13.5 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Helitron_like_N PF14214.6 CEP09088.1 - 1.6e-31 110.0 0.4 1e-19 71.5 0.0 2.5 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus Leo1 PF04004.13 CEP09090.1 - 2.5e-45 154.3 0.3 2.5e-45 154.3 0.3 2.7 2 0 0 2 2 2 1 Leo1-like protein AGP PF06376.12 CEP09092.1 - 0.53 10.2 2.3 1.4 8.9 1.8 2.0 2 0 0 2 2 2 0 Arabinogalactan peptide RT_RNaseH_2 PF17919.1 CEP09093.1 - 4.8e-13 49.0 0.0 7.5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP09094.1 - 1.3e-15 57.6 0.0 1.8e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CEP09094.1 - 5.4e-05 23.4 0.2 6.6e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 DDE domain AbiJ_NTD4 PF18863.1 CEP09094.1 - 0.045 14.2 0.0 0.061 13.8 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 DUF3813 PF12758.7 CEP09094.1 - 0.047 14.0 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) DUF5104 PF17117.5 CEP09094.1 - 0.096 13.1 0.1 0.36 11.3 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) gag-asp_proteas PF13975.6 CEP09096.1 - 0.00015 22.3 0.0 0.00041 20.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP09096.1 - 0.00015 22.3 0.0 0.00038 21.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CEP09096.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 CEP09096.1 - 0.029 14.6 0.2 0.065 13.5 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Cwf_Cwc_15 PF04889.12 CEP09097.1 - 4.6 6.9 11.0 5.1 6.8 11.0 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SET PF00856.28 CEP09099.1 - 6.7e-20 72.1 1.3 6.4e-19 69.0 1.3 2.3 1 1 0 1 1 1 1 SET domain AWS PF17907.1 CEP09099.1 - 4.3e-18 65.0 7.8 4.3e-18 65.0 7.8 2.4 3 0 0 3 3 3 1 AWS domain GATA PF00320.27 CEP09099.1 - 3.3e-17 61.8 13.7 2.6e-12 46.1 5.7 2.9 2 0 0 2 2 2 2 GATA zinc finger DDE_3 PF13358.6 CEP09100.1 - 1.7e-06 27.9 0.0 2.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Usp PF00582.26 CEP09102.1 - 5.6e-27 95.0 0.1 6e-26 91.6 0.1 1.9 1 1 0 1 1 1 1 Universal stress protein family CorA PF01544.18 CEP09103.1 - 4.1e-08 32.9 0.2 6.9e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Dynactin_p22 PF07426.11 CEP09103.1 - 0.011 15.6 1.8 0.057 13.3 0.2 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 SCP2 PF02036.17 CEP09104.1 - 2e-09 37.9 0.7 3.8e-09 36.9 0.7 1.5 1 1 0 1 1 1 1 SCP-2 sterol transfer family Ribosomal_L5e PF17144.4 CEP09104.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 ACOX PF01756.19 CEP09105.1 - 3.9e-51 173.2 0.1 7.4e-51 172.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEP09105.1 - 1.6e-25 90.1 2.0 4.6e-25 88.6 0.7 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEP09105.1 - 2e-13 50.3 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP09105.1 - 3e-05 24.3 0.4 9.6e-05 22.6 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain PRP21_like_P PF12230.8 CEP09106.1 - 3.1e-56 190.7 9.6 8.3e-56 189.3 9.6 1.7 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CEP09106.1 - 5e-29 100.0 3.7 3.3e-17 62.2 0.3 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 CEP09106.1 - 4.9e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 CEP09106.1 - 0.00019 20.9 0.1 0.00047 19.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Adaptin_binding PF10199.9 CEP09106.1 - 0.015 15.9 0.4 0.059 14.0 0.4 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Mis14 PF08641.12 CEP09107.1 - 0.00087 19.6 1.9 0.00087 19.6 1.9 1.8 2 1 0 2 2 2 1 Kinetochore protein Mis14 like IFT57 PF10498.9 CEP09107.1 - 0.0057 15.7 1.1 0.0087 15.1 0.8 1.4 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3562 PF12085.8 CEP09107.1 - 0.029 14.0 0.1 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) FTA4 PF13093.6 CEP09107.1 - 0.036 14.0 1.4 0.049 13.5 1.4 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3482 PF11981.8 CEP09107.1 - 0.19 11.1 0.7 9.7 5.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) GCD14 PF08704.10 CEP09108.1 - 2.9e-89 299.0 0.0 3.4e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CEP09108.1 - 1.1e-07 31.8 0.0 3e-07 30.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CEP09108.1 - 3.4e-05 23.7 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 CEP09108.1 - 0.0015 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 CEP09108.1 - 0.033 14.9 0.0 0.069 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain vATP-synt_AC39 PF01992.16 CEP09109.1 - 4.5e-102 342.0 1.7 5.8e-99 331.8 1.8 2.0 1 1 1 2 2 2 2 ATP synthase (C/AC39) subunit Guanylate_cyc PF00211.20 CEP09110.1 - 3.3e-21 75.7 0.0 1.2e-20 73.9 0.0 1.9 1 1 1 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CEP09111.1 - 1.4e-59 201.7 0.0 2.8e-59 200.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09111.1 - 3.4e-44 151.1 0.0 5.8e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP09111.1 - 8.6e-06 24.8 0.0 1.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP09111.1 - 1.9e-05 24.1 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP09111.1 - 0.051 13.5 0.1 0.42 10.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0449 PF15136.6 CEP09111.1 - 0.092 13.2 3.9 0.25 11.8 3.9 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 YabA PF06156.13 CEP09111.1 - 0.26 11.9 10.8 0.088 13.5 4.3 2.7 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 CEP09111.1 - 0.52 10.1 5.3 1.6 8.6 5.3 1.8 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 CEP09111.1 - 0.52 10.6 5.7 2 8.7 5.7 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CEP09111.1 - 0.54 10.4 11.3 20 5.4 11.1 2.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF5094 PF17015.5 CEP09111.1 - 4.4 7.4 6.2 10 6.2 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Metallophos PF00149.28 CEP09112.1 - 5.8e-37 128.2 0.1 9.2e-37 127.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP09112.1 - 3.2e-13 49.9 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB PF00651.31 CEP09114.1 - 6e-08 32.9 0.1 3.2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain RXT2_N PF08595.11 CEP09114.1 - 0.16 12.0 5.7 2.4 8.1 0.1 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal PRP1_N PF06424.12 CEP09115.1 - 1.1e-51 175.2 4.5 2.1e-51 174.2 4.5 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CEP09115.1 - 7.5e-35 116.6 16.8 0.00048 20.7 0.0 14.3 4 3 11 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 CEP09115.1 - 4.2e-27 94.5 5.6 4.4e-06 27.1 0.0 10.2 8 3 3 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 CEP09115.1 - 7.4e-15 53.8 11.3 0.0057 16.7 0.0 12.3 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP09115.1 - 3.7e-14 53.1 0.1 0.0017 19.0 0.0 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP09115.1 - 1.2e-12 47.3 0.2 0.17 12.3 0.0 10.0 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09115.1 - 1.9e-12 46.3 8.1 0.073 13.3 0.0 8.8 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP09115.1 - 8.4e-12 44.6 0.0 0.00033 20.3 0.0 6.0 7 0 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 CEP09115.1 - 4.4e-09 35.8 0.0 0.048 13.5 0.0 5.7 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP09115.1 - 2.2e-08 34.2 8.5 4.1 8.3 0.0 10.0 12 1 0 12 12 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 CEP09115.1 - 4.6e-07 29.7 11.1 0.016 14.9 1.7 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 CEP09115.1 - 2.1e-06 27.9 1.9 0.55 10.6 0.0 6.6 5 2 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP09115.1 - 5.1e-05 23.4 0.8 3 8.1 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 CEP09115.1 - 6e-05 23.0 1.0 1.6 8.6 0.0 3.8 3 1 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 CEP09115.1 - 0.00011 21.6 14.3 0.014 14.7 0.1 5.4 3 2 3 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 CEP09115.1 - 0.00018 20.6 11.0 0.0094 14.9 0.0 5.0 4 1 2 6 6 6 2 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 CEP09115.1 - 0.00021 20.2 0.4 0.27 9.9 0.0 2.7 2 1 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CEP09115.1 - 0.00044 20.4 0.1 2.5 8.3 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.14 CEP09115.1 - 0.018 15.0 0.5 7.2 6.5 0.0 4.6 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) DUF2786 PF10979.8 CEP09115.1 - 0.95 9.4 4.8 4.8 7.2 0.1 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF2786) rve PF00665.26 CEP09116.1 - 2.7e-09 37.3 0.1 2.2e-08 34.3 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 CEP09116.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain SPASM PF13186.6 CEP09116.1 - 0.14 12.7 0.1 0.51 10.9 0.1 2.1 1 1 0 1 1 1 0 Iron-sulfur cluster-binding domain rve PF00665.26 CEP09117.1 - 1.3e-15 57.6 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP09117.1 - 1.7e-14 53.7 0.1 3.5e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 CEP09117.1 - 0.014 15.6 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 DDE domain DDE_3 PF13358.6 CEP09117.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease FSIP2 PF15783.5 CEP09117.1 - 0.073 11.0 0.1 0.099 10.6 0.1 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 BSD PF03909.17 CEP09118.1 - 0.033 14.2 3.5 2.6 8.1 0.5 2.7 2 0 0 2 2 2 0 BSD domain PLAC9 PF15205.6 CEP09118.1 - 2.4 8.6 3.6 2.6 8.5 0.2 2.7 4 0 0 4 4 4 0 Placenta-specific protein 9 Rep_fac_C PF08542.11 CEP09119.1 - 0.24 11.8 3.1 0.36 11.2 0.3 2.6 2 1 0 2 2 2 0 Replication factor C C-terminal domain FadA PF09403.10 CEP09119.1 - 0.28 11.7 22.6 0.065 13.7 2.6 4.3 1 1 3 4 4 4 0 Adhesion protein FadA Mucin15 PF15672.5 CEP09119.1 - 1 8.8 7.6 0.25 10.8 0.9 2.1 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 TcdB_N PF12918.7 CEP09119.1 - 2.3 8.6 15.6 4.4 7.7 0.2 4.8 5 0 0 5 5 5 0 TcdB toxin N-terminal helical domain Cyt-b5 PF00173.28 CEP09121.1 - 5.9e-09 35.9 0.1 7.5e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PIP5K PF01504.18 CEP09125.1 - 3.3e-36 124.9 4.8 1.3e-32 113.2 4.2 5.2 4 1 1 5 5 5 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CEP09125.1 - 9.5e-17 60.8 0.0 1.2e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family AviRa PF11599.8 CEP09125.1 - 0.18 11.2 1.8 0.81 9.1 0.1 2.8 2 0 0 2 2 2 0 RRNA methyltransferase AviRa A2L_zn_ribbon PF08792.10 CEP09125.1 - 2.3 8.0 14.1 0.24 11.2 2.7 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain RabGAP-TBC PF00566.18 CEP09126.1 - 1.9e-55 187.8 0.2 1.9e-55 187.8 0.2 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain SUIM_assoc PF16619.5 CEP09126.1 - 0.093 12.8 11.8 0.087 12.9 2.5 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 APG6_N PF17675.1 CEP09126.1 - 0.73 10.4 21.6 0.32 11.5 1.2 3.4 3 1 0 3 3 3 0 Apg6 coiled-coil region Gln-synt_C PF00120.24 CEP09127.1 - 2.7e-18 66.1 0.0 1.6e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CEP09127.1 - 2e-12 46.6 0.0 3.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RVT_1 PF00078.27 CEP09128.1 - 3.5e-05 23.4 0.0 9.7e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP09128.1 - 0.00066 20.3 0.5 0.0018 18.9 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP09129.1 - 1.8e-06 27.6 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP09129.1 - 0.0001 22.2 13.3 0.0054 16.7 1.5 2.6 2 0 0 2 2 2 2 Zinc knuckle Exo_endo_phos_2 PF14529.6 CEP09129.1 - 0.03 14.2 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-CCHC_4 PF14392.6 CEP09129.1 - 0.033 13.9 3.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF3464 PF11947.8 CEP09131.1 - 0.22 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Hamartin PF04388.12 CEP09132.1 - 0.38 9.4 17.5 0.46 9.1 17.5 1.1 1 0 0 1 1 1 0 Hamartin protein Amidohydro_3 PF07969.11 CEP09133.1 - 8.3e-05 22.2 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family FOXO-TAD PF16676.5 CEP09133.1 - 0.062 13.7 0.1 21 5.6 0.0 2.4 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family Ribosomal_L30 PF00327.20 CEP09138.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e RVT_1 PF00078.27 CEP09139.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WRNPLPNID PF15017.6 CEP09139.1 - 0.19 12.6 0.6 1.7 9.6 0.0 2.3 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box Helitron_like_N PF14214.6 CEP09140.1 - 5.9e-32 111.4 0.1 7.3e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus NDC10_II PF16787.5 CEP09141.1 - 1.8e-16 60.1 0.1 2.1e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Retrotran_gag_2 PF14223.6 CEP09142.1 - 0.03 14.0 0.5 0.03 14.0 0.5 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type CNOT1_TTP_bind PF16417.5 CEP09142.1 - 0.05 12.8 0.7 0.11 11.7 0.7 1.5 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain zf-RVT PF13966.6 CEP09144.1 - 1.2e-06 29.2 0.2 2.3e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PPP4R2 PF09184.11 CEP09145.1 - 0.14 11.8 4.1 0.15 11.6 4.1 1.1 1 0 0 1 1 1 0 PPP4R2 SOG2 PF10428.9 CEP09145.1 - 0.77 8.9 14.4 0.88 8.7 14.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 CEP09145.1 - 1.8 6.6 13.9 1.8 6.6 13.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RVT_1 PF00078.27 CEP09146.1 - 2.6e-11 43.5 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAM2 PF07145.15 CEP09147.1 - 0.028 14.1 0.6 0.071 12.8 0.6 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-RVT PF13966.6 CEP09149.1 - 0.00052 20.7 0.5 0.0011 19.6 0.5 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phytochelatin PF05023.14 CEP09151.1 - 2.6e-45 154.3 0.0 3.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Velvet PF11754.8 CEP09152.1 - 3.3e-48 164.8 2.8 3.3e-48 164.8 2.8 3.8 2 2 0 2 2 2 1 Velvet factor TBK1_ULD PF18396.1 CEP09153.1 - 0.14 12.1 0.1 0.2 11.6 0.1 1.3 1 1 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain MFS_1 PF07690.16 CEP09154.1 - 5.1e-12 45.4 21.9 1.3e-09 37.4 9.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L13 PF00572.18 CEP09155.1 - 1.8e-09 37.9 0.0 9.8e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 MRP-S33 PF08293.11 CEP09156.1 - 3.5e-28 97.7 0.1 4.3e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GATA PF00320.27 CEP09157.1 - 2.2e-13 49.6 5.1 2.2e-13 49.6 5.1 2.0 2 0 0 2 2 2 1 GATA zinc finger Cut8 PF08559.10 CEP09158.1 - 1.4e-11 44.5 1.3 1.4e-11 44.5 1.3 1.3 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein FXR_C1 PF16096.5 CEP09158.1 - 0.18 12.0 1.6 0.39 10.9 1.6 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 EF-hand_7 PF13499.6 CEP09159.1 - 2.5e-10 40.7 4.8 0.00016 22.0 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEP09159.1 - 2.4e-07 29.8 1.8 4.6e-06 25.8 0.1 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CEP09159.1 - 1.2e-05 24.9 0.4 0.014 15.3 0.0 3.1 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CEP09159.1 - 5.4e-05 23.0 1.5 0.0052 16.6 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CEP09159.1 - 0.0047 16.4 0.0 0.017 14.6 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.6 CEP09159.1 - 0.041 14.2 0.3 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain CheD PF03975.13 CEP09159.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction KIND PF16474.5 CEP09159.1 - 0.28 11.1 4.6 0.39 10.6 4.6 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Ribosomal_L22 PF00237.19 CEP09160.1 - 3.3e-40 136.5 0.1 4.3e-40 136.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S6e PF01092.19 CEP09161.1 - 3.4e-57 191.8 1.6 3.7e-57 191.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Arm-DNA-bind_4 PF14657.6 CEP09161.1 - 3 7.7 8.0 21 5.0 0.4 3.4 3 0 0 3 3 3 0 Arm DNA-binding domain IF4E PF01652.18 CEP09162.1 - 8.9e-55 184.8 2.8 1.2e-54 184.5 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Fungal_trans PF04082.18 CEP09163.1 - 3.3e-13 49.3 0.1 8.3e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP09163.1 - 0.01 16.0 11.8 0.023 14.8 11.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Botulinum_HA-17 PF05588.11 CEP09163.1 - 0.096 12.8 2.7 0.1 12.7 0.9 1.9 2 0 0 2 2 2 0 Clostridium botulinum HA-17 domain Carbpep_Y_N PF05388.11 CEP09164.1 - 0.096 13.2 3.8 0.37 11.4 3.8 2.0 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Eno-Rase_FAD_bd PF07055.12 CEP09164.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain AAA_10 PF12846.7 CEP09164.1 - 0.45 9.4 8.9 0.35 9.7 7.1 1.6 1 1 0 1 1 1 0 AAA-like domain V-ATPase_H_N PF03224.14 CEP09165.1 - 9e-79 265.0 3.7 8.7e-78 261.8 3.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CEP09165.1 - 2.4e-37 127.6 3.7 1e-36 125.6 0.1 2.9 2 1 1 3 3 3 1 V-ATPase subunit H Arm PF00514.23 CEP09165.1 - 0.00041 20.3 0.1 0.46 10.6 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP09165.1 - 0.0031 17.9 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats DUF2985 PF11204.8 CEP09165.1 - 0.023 14.9 0.3 0.055 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) ParcG PF10274.9 CEP09165.1 - 0.031 14.4 1.0 0.14 12.3 0.3 2.3 1 1 2 3 3 3 0 Parkin co-regulated protein Aminotran_1_2 PF00155.21 CEP09166.1 - 2e-43 149.0 0.0 2.6e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NDUF_B12 PF08122.12 CEP09167.1 - 1.5e-24 85.7 0.6 1.8e-24 85.5 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF3772 PF12607.8 CEP09170.1 - 0.028 14.2 0.9 0.073 12.8 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) YqcI_YcgG PF08892.11 CEP09170.1 - 0.048 13.5 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 YqcI/YcgG family Peptidase_C78 PF07910.13 CEP09171.1 - 5.5e-56 189.4 0.1 8.7e-56 188.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 PSD1 PF07587.11 CEP09171.1 - 0.011 15.2 0.0 0.042 13.3 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1553) Peptidase_C54 PF03416.19 CEP09171.1 - 0.093 12.1 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C54 AcetylCoA_hydro PF02550.15 CEP09172.1 - 1.2e-50 172.2 0.0 1.7e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CEP09172.1 - 2.6e-40 137.9 0.0 3.9e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AA_permease_2 PF13520.6 CEP09173.1 - 4.3e-59 200.4 55.4 5.5e-59 200.1 55.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP09173.1 - 2.6e-27 95.6 43.9 3.5e-27 95.1 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 CEP09174.1 - 4.1e-51 173.9 0.0 6e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09174.1 - 2.1e-19 69.8 0.0 7.5e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP09174.1 - 1.1e-08 34.8 0.0 4.8e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP09174.1 - 3.2e-05 23.4 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP09174.1 - 0.00053 18.9 0.2 0.002 17.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CEP09174.1 - 0.009 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CEP09174.1 - 0.012 15.6 1.7 0.013 15.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family TetR_C_27 PF17935.1 CEP09174.1 - 0.089 12.9 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Radical_SAM_C PF16199.5 CEP09174.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Radical_SAM C-terminal domain DDE_1 PF03184.19 CEP09176.1 - 1.3e-18 67.3 0.4 1.6e-18 67.0 0.4 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MIF4G PF02854.19 CEP09178.1 - 9.2e-46 156.2 3.0 1.9e-45 155.1 3.0 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 CEP09178.1 - 6.6e-16 58.3 3.1 7.1e-16 58.2 1.3 2.0 2 0 0 2 2 2 1 MA3 domain eIF_4G1 PF12152.8 CEP09178.1 - 2.1e-07 31.0 2.3 6.1e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF4062 PF13271.6 CEP09178.1 - 0.04 14.3 0.0 0.16 12.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) CDT1 PF08839.11 CEP09179.1 - 4.8e-09 36.8 0.1 4.8e-09 36.8 0.1 2.6 2 1 0 2 2 2 1 DNA replication factor CDT1 like Peptidase_M22 PF00814.25 CEP09180.1 - 4.4e-74 249.6 0.0 1.2e-73 248.1 0.0 1.6 1 1 0 1 1 1 1 Glycoprotease family NUC129 PF08157.11 CEP09181.1 - 0.036 14.4 0.1 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 NUC129 domain Mistic PF11458.8 CEP09181.1 - 0.038 13.9 0.5 0.14 12.2 0.2 2.0 1 1 1 2 2 2 0 Membrane-integrating protein Mistic Pkinase PF00069.25 CEP09182.1 - 7.6e-75 251.7 0.0 9.6e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09182.1 - 2.5e-36 125.3 0.0 3.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP09182.1 - 2.2e-07 30.5 0.0 3.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEP09182.1 - 0.0018 18.0 0.2 0.058 13.0 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CEP09182.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 SBBP PF06739.11 CEP09183.1 - 0.013 15.5 0.0 0.087 12.8 0.0 2.4 2 0 0 2 2 2 0 Beta-propeller repeat Fasciclin PF02469.22 CEP09184.1 - 1.5e-65 219.2 5.8 2.8e-21 76.1 0.4 5.5 5 0 0 5 5 5 5 Fasciclin domain MFS_1 PF07690.16 CEP09184.1 - 1.1e-26 93.7 36.8 1.1e-26 93.7 36.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Maff2 PF12750.7 CEP09184.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.9 3 0 0 3 3 3 0 Maff2 family Chorion_3 PF05387.11 CEP09184.1 - 0.057 13.1 0.7 0.11 12.1 0.7 1.4 1 0 0 1 1 1 0 Chorion family 3 SAPIS-gp6 PF16722.5 CEP09184.1 - 2.2 8.7 4.6 6.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Pathogenicity island protein gp6 in Staphylococcus zf-Nse PF11789.8 CEP09185.1 - 1.6e-15 56.7 0.9 3.3e-15 55.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 CEP09185.1 - 0.0063 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 CEP09185.1 - 0.0073 16.4 1.6 0.012 15.7 1.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CEP09185.1 - 0.011 15.8 1.3 0.02 14.9 1.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEP09185.1 - 0.034 14.0 0.3 0.064 13.1 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP09185.1 - 0.11 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAGK_acc PF00609.19 CEP09186.1 - 6e-18 65.7 0.0 1e-17 65.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CEP09186.1 - 1.2e-13 50.8 0.0 9.5e-13 47.9 0.0 2.4 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain Usp PF00582.26 CEP09187.1 - 4.1e-23 82.5 0.1 5.4e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family FBP_C PF16571.5 CEP09187.1 - 0.0077 15.8 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger THF_DHG_CYH PF00763.23 CEP09189.1 - 0.11 12.7 0.4 0.64 10.3 0.1 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DDE_Tnp_1_7 PF13843.6 CEP09191.1 - 5e-22 78.7 0.0 6.2e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 rve PF00665.26 CEP09192.1 - 6.3e-20 71.5 0.0 8.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain YpjP PF14005.6 CEP09193.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.6 3 1 0 3 3 3 0 YpjP-like protein DUF5399 PF17377.2 CEP09194.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5399) zf-C2H2_4 PF13894.6 CEP09194.1 - 0.23 12.4 0.1 0.23 12.4 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP09194.1 - 1 10.0 0.1 1 10.0 0.1 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CEP09194.1 - 4 7.8 7.6 1.5 9.2 1.3 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 CEP09195.1 - 0.22 10.0 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) RVT_1 PF00078.27 CEP09196.1 - 1.2e-30 106.7 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP09197.1 - 1.5e-22 79.4 0.3 2.3e-22 78.9 0.3 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP09197.1 - 0.015 15.5 0.1 0.036 14.3 0.0 1.7 2 0 0 2 2 2 0 H2C2 zinc finger Integrase_H2C2 PF17921.1 CEP09198.1 - 2.8e-15 56.2 0.5 7.5e-15 54.8 0.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP09198.1 - 1.3e-12 47.9 0.0 6.5e-10 39.2 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain rve_3 PF13683.6 CEP09198.1 - 0.0028 17.4 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP09198.1 - 0.066 13.4 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger NMT_C PF02799.15 CEP09199.1 - 1.1e-79 266.8 0.9 1.1e-79 266.8 0.9 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CEP09199.1 - 1.9e-73 245.6 0.5 8.8e-73 243.4 0.1 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 CEP09199.1 - 0.0026 18.0 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HIG_1_N PF04588.13 CEP09200.1 - 7.7e-07 29.2 0.9 7.7e-07 29.2 0.9 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 CEP09200.1 - 0.018 14.9 0.2 0.036 13.9 0.0 1.5 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein FAD_oxidored PF12831.7 CEP09200.1 - 0.1 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Romo1 PF10247.9 CEP09200.1 - 0.3 11.5 4.4 0.14 12.5 1.1 1.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Prp19 PF08606.11 CEP09201.1 - 1.8e-33 114.3 2.5 3.5e-33 113.4 2.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CEP09201.1 - 2e-25 88.5 14.2 0.0002 22.1 0.0 7.4 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09201.1 - 1e-17 64.2 0.1 0.00022 21.4 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1631 PF07793.11 CEP09201.1 - 0.0015 17.1 2.8 0.002 16.7 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) DUF3450 PF11932.8 CEP09201.1 - 0.0055 16.0 1.6 0.013 14.8 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Nup160 PF11715.8 CEP09201.1 - 0.007 15.1 1.6 0.32 9.6 0.0 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP09201.1 - 0.0073 15.3 0.2 0.078 11.9 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein U-box PF04564.15 CEP09201.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain WD40_like PF17005.5 CEP09201.1 - 0.04 13.2 0.5 0.97 8.7 0.0 2.6 2 2 1 3 3 3 0 WD40-like domain DUF4253 PF14062.6 CEP09201.1 - 0.066 13.4 0.4 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) zf-Nse PF11789.8 CEP09201.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_60s PF00428.19 CEP09201.1 - 0.46 11.1 5.9 1.4 9.6 5.9 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Metal_resist PF13801.6 CEP09201.1 - 1.3 9.3 10.1 2.3 8.4 7.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Amino_oxidase PF01593.24 CEP09203.1 - 1.1e-26 94.1 0.0 1.3e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP09203.1 - 2.8e-09 37.1 0.0 7.7e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP09203.1 - 2.6e-07 30.5 0.0 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEP09203.1 - 0.00059 19.1 0.7 0.0014 17.9 0.2 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CEP09203.1 - 0.0021 18.6 0.1 0.073 13.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEP09203.1 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP09203.1 - 0.017 15.1 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CEP09203.1 - 0.04 12.8 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 CEP09203.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 CEP09203.1 - 0.12 11.5 0.2 0.7 8.9 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-H2C2_2 PF13465.6 CEP09204.1 - 2.1e-11 43.7 19.2 1.6e-06 28.3 3.9 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP09204.1 - 8.1e-10 38.6 16.4 6.7e-06 26.3 3.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP09204.1 - 3.8e-06 27.3 9.9 0.0083 16.9 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP09204.1 - 0.0032 18.1 1.0 0.0032 18.1 1.0 1.8 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CEP09204.1 - 0.0076 16.5 1.6 0.36 11.2 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CEP09204.1 - 0.071 13.4 3.4 0.16 12.3 3.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CEP09204.1 - 0.28 11.0 11.7 0.45 10.3 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ATG7_N PF16420.5 CEP09205.1 - 6.1e-83 278.9 0.1 8.1e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CEP09205.1 - 3.7e-45 154.2 0.0 5.5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CEP09205.1 - 0.012 15.7 0.0 0.43 10.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Evr1_Alr PF04777.13 CEP09206.1 - 4.4e-28 97.7 6.9 1.1e-27 96.5 5.4 2.5 2 0 0 2 2 2 1 Erv1 / Alr family Zn_clus PF00172.18 CEP09207.1 - 0.0047 17.0 8.5 0.011 15.9 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Hsk3 PF08227.11 CEP09207.1 - 0.055 13.8 0.2 0.21 11.9 0.2 2.0 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like dCMP_cyt_deam_1 PF00383.23 CEP09208.1 - 2.5e-12 46.5 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP09208.1 - 3.3e-06 26.9 0.0 1.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CEP09208.1 - 0.00047 20.2 0.4 0.0032 17.5 0.4 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase DIOX_N PF14226.6 CEP09209.1 - 1.8e-19 70.6 0.0 3.3e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEP09209.1 - 1.1e-16 61.1 0.0 2.4e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SRPRB PF09439.10 CEP09209.1 - 0.022 14.2 0.5 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DNA_pol_lambd_f PF10391.9 CEP09209.1 - 0.069 13.0 0.0 6.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda adh_short PF00106.25 CEP09210.1 - 8.2e-46 155.9 4.0 1.1e-45 155.5 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP09210.1 - 1.5e-31 109.8 2.7 1.8e-31 109.5 2.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP09210.1 - 7.1e-07 29.3 1.7 3.4e-06 27.1 0.7 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CEP09210.1 - 2.2e-05 24.1 0.3 4.5e-05 23.0 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEP09210.1 - 0.0027 16.9 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 CEP09210.1 - 0.037 13.8 0.1 0.071 12.9 0.1 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 CEP09210.1 - 0.049 13.6 1.3 0.32 11.0 1.1 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TauD PF02668.16 CEP09212.1 - 2.8e-28 99.5 0.0 4.6e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CEP09212.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 CsiD WD40 PF00400.32 CEP09213.1 - 1e-67 222.4 29.0 3.8e-11 43.4 0.2 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09213.1 - 1.8e-23 82.7 4.4 2.4e-05 24.5 0.1 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP09213.1 - 6.5e-14 51.6 0.1 0.00067 18.7 0.0 4.7 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 CEP09213.1 - 4.3e-12 46.4 0.0 9.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 CEP09213.1 - 2.9e-09 37.1 0.3 0.0038 17.1 0.0 3.6 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CEP09213.1 - 1.5e-07 31.0 1.5 0.047 13.0 0.0 4.3 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CEP09213.1 - 7.4e-07 28.2 4.4 1.1 7.8 0.0 5.9 5 1 1 6 6 6 1 Nucleoporin Nup120/160 PD40 PF07676.12 CEP09213.1 - 3.4e-06 26.8 5.6 0.41 10.6 0.1 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 CEP09213.1 - 0.0017 16.4 1.4 0.2 9.6 0.0 2.4 2 1 0 2 2 2 2 IKI3 family Frtz PF11768.8 CEP09213.1 - 0.002 16.5 0.0 1 7.6 0.0 2.5 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz FAD_binding_9 PF08021.11 CEP09213.1 - 0.022 15.0 0.0 12 6.1 0.0 2.6 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain Proteasome_A_N PF10584.9 CEP09213.1 - 0.033 13.9 1.1 2.3 8.0 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40_like PF17005.5 CEP09213.1 - 0.065 12.6 0.0 18 4.6 0.0 3.8 4 1 1 5 5 5 0 WD40-like domain Nucleoporin_N PF08801.11 CEP09213.1 - 0.17 10.6 4.4 16 4.1 0.0 3.4 2 1 0 2 2 2 0 Nup133 N terminal like Dus PF01207.17 CEP09214.1 - 1.5e-78 264.0 0.0 2e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 CEP09214.1 - 0.0014 18.5 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 SOR/SNZ family NMO PF03060.15 CEP09214.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 CEP09214.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 CEP09214.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 CEP09214.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 CEP09214.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AadA_C PF18280.1 CEP09214.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain SBF_like PF13593.6 CEP09215.1 - 5.3e-87 292.0 20.7 6.5e-87 291.8 20.7 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CEP09215.1 - 6.8e-11 42.2 12.5 6.8e-11 42.2 12.5 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Synaptobrevin PF00957.21 CEP09215.1 - 0.0042 16.8 0.1 0.0042 16.8 0.1 2.5 4 0 0 4 4 4 1 Synaptobrevin COX6B PF02297.17 CEP09216.1 - 5.6e-24 84.2 1.5 6.4e-24 84.0 1.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 CEP09216.1 - 0.0043 17.3 1.7 0.085 13.2 0.1 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 OTU PF02338.19 CEP09217.1 - 6e-24 84.9 0.0 1.3e-23 83.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CEP09217.1 - 8.3e-06 25.4 0.7 1.6e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 Peptidase C65 Otubain Borrelia_REV PF03978.13 CEP09217.1 - 0.039 13.9 0.4 0.072 13.0 0.4 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein E1_UFD PF09358.10 CEP09217.1 - 0.056 14.2 0.2 2.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin fold domain PMSR PF01625.21 CEP09218.1 - 5.8e-60 201.9 1.0 6.7e-60 201.7 1.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CdvA PF18822.1 CEP09218.1 - 0.096 12.5 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain TFIIIC_delta PF12657.7 CEP09219.1 - 2.1e-11 44.1 0.4 6.4e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term DUF1479 PF07350.12 CEP09221.1 - 1.1e-69 235.2 0.3 6.1e-39 134.0 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 CEP09221.1 - 0.0014 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PCI PF01399.27 CEP09222.1 - 2.2e-14 53.8 0.1 7.6e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain Exonuc_V_gamma PF04257.14 CEP09222.1 - 0.015 13.5 0.5 0.062 11.5 0.0 1.9 2 0 0 2 2 2 0 Exodeoxyribonuclease V, gamma subunit Rpn9_C PF18261.1 CEP09222.1 - 0.032 13.8 0.8 0.064 12.9 0.1 1.9 2 0 0 2 2 2 0 Rpn9 C-terminal helix PDCD7 PF16021.5 CEP09223.1 - 5.5e-12 45.4 33.1 9.7e-10 38.0 33.1 2.6 1 1 0 1 1 1 1 Programmed cell death protein 7 Tubulin_3 PF14881.6 CEP09224.1 - 4.9e-47 159.9 0.0 8.9e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CEP09224.1 - 2e-37 128.1 0.4 5.4e-37 126.7 0.2 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CEP09224.1 - 3.3e-08 34.0 0.1 0.00034 20.9 0.1 2.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Cir_N PF10197.9 CEP09225.1 - 4.2e-10 39.6 3.2 4.2e-10 39.6 3.2 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR NDT80_PhoG PF05224.12 CEP09226.1 - 4.7e-25 88.9 0.3 4.7e-25 88.9 0.3 4.1 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Tfb4 PF03850.14 CEP09226.1 - 0.39 10.2 4.8 0.63 9.5 4.8 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 AFG1_ATPase PF03969.16 CEP09227.1 - 1.2e-109 366.6 1.9 3.9e-104 348.4 0.5 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CEP09227.1 - 4.2e-06 27.3 0.5 0.014 15.8 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CEP09227.1 - 0.00039 20.7 0.0 0.0016 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP09227.1 - 0.0037 17.3 0.0 0.0089 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEP09227.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CEP09227.1 - 0.087 12.7 0.0 0.71 9.8 0.0 2.4 1 1 0 1 1 1 0 NACHT domain ARID PF01388.21 CEP09228.1 - 2.2e-19 69.9 0.0 6.3e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2_aberr PF17017.5 CEP09228.1 - 0.0024 18.0 3.1 0.0053 16.9 3.1 1.6 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 CEP09228.1 - 0.12 13.0 5.5 4.3 8.0 0.5 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 CEP09228.1 - 2.5 8.7 4.7 6.6 7.4 0.6 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type GATA PF00320.27 CEP09229.1 - 3.9e-15 55.2 4.2 3.9e-15 55.2 4.2 2.0 1 1 1 2 2 2 1 GATA zinc finger Cytochrom_c3_2 PF14537.6 CEP09229.1 - 0.067 13.7 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 Cytochrome c3 OmpH PF03938.14 CEP09229.1 - 0.76 10.1 7.4 1.1 9.6 7.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) tRNA-synt_2b PF00587.25 CEP09230.1 - 1.3e-16 61.1 0.0 3.2e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CEP09230.1 - 2.4e-14 53.5 0.4 4.5e-14 52.6 0.4 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DEK_C PF08766.11 CEP09231.1 - 3.5e-05 23.6 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 DEK C terminal domain Cwf_Cwc_15 PF04889.12 CEP09231.1 - 0.56 9.9 62.1 0.79 9.4 30.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-O PF09496.10 CEP09232.1 - 5e-09 36.5 4.1 5e-09 36.5 4.1 1.9 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component VHS PF00790.19 CEP09233.1 - 5.3e-32 110.6 0.1 1e-31 109.7 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CEP09233.1 - 3.8e-18 64.8 2.5 5.3e-17 61.2 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CEP09233.1 - 8.2e-16 57.6 0.2 1.8e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP09233.1 - 2.7e-13 49.4 0.1 1.2e-12 47.3 0.3 2.0 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 CEP09233.1 - 6.1e-13 48.9 1.9 2.4e-12 47.0 1.9 2.1 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 CEP09233.1 - 0.0033 17.2 2.5 0.0092 15.8 2.5 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF3361 PF11841.8 CEP09233.1 - 0.12 12.3 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Trypsin PF00089.26 CEP09234.1 - 2.8e-21 76.4 0.0 2.4e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CEP09234.1 - 0.00078 20.4 0.0 0.0014 19.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain GshA PF08886.11 CEP09234.1 - 0.065 11.8 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Sterol_MT_C PF08498.10 CEP09235.1 - 0.061 13.6 0.0 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal DDE_3 PF13358.6 CEP09236.1 - 1.4e-16 60.5 0.0 4.9e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP09236.1 - 4.7e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CEP09236.1 - 8.7e-06 25.4 0.4 0.00043 20.0 0.1 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP09236.1 - 4.9e-05 23.3 0.1 0.00047 20.1 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CEP09236.1 - 0.00023 21.2 0.5 0.0015 18.6 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CEP09236.1 - 0.0039 16.6 0.1 0.01 15.2 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 CEP09236.1 - 0.0058 16.8 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP09236.1 - 0.026 14.8 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 Transposase Terminase_5 PF06056.12 CEP09236.1 - 0.027 14.4 0.3 0.086 12.7 0.1 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 CEP09236.1 - 0.16 12.5 0.1 1.1 9.9 0.1 2.2 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 ProRS-C_1 PF09180.11 CEP09237.1 - 3.3e-12 46.4 0.0 5.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 CEP09237.1 - 2.6e-05 24.3 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain NADH_4Fe-4S PF10589.9 CEP09237.1 - 0.091 12.8 0.6 0.091 12.8 0.6 1.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Integrase_H2C2 PF17921.1 CEP09240.1 - 2.6e-11 43.4 0.4 7e-11 42.1 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP09240.1 - 5e-09 36.4 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP09240.1 - 0.00077 19.6 0.8 0.0017 18.6 0.8 1.6 1 0 0 1 1 1 1 H2C2 zinc finger SLATT_4 PF18186.1 CEP09241.1 - 0.014 15.0 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 FWWh PF14922.6 CEP09241.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF934 PF06073.12 CEP09242.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) HTH_23 PF13384.6 CEP09243.1 - 4.8e-05 23.0 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEP09243.1 - 0.00069 19.9 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Transposase DUF1804 PF08822.11 CEP09243.1 - 0.0058 16.6 0.1 0.0088 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Gar1 PF04410.14 CEP09243.1 - 0.066 13.0 2.4 0.085 12.6 1.9 1.4 1 1 0 1 1 1 0 Gar1/Naf1 RNA binding region YdaS_antitoxin PF15943.5 CEP09243.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 CEP09243.1 - 0.097 12.8 0.6 0.4 10.8 0.0 2.2 3 0 0 3 3 3 0 MerR HTH family regulatory protein Pkinase PF00069.25 CEP09244.1 - 6e-80 268.4 0.0 1.4e-28 100.0 0.0 4.6 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09244.1 - 8.5e-43 146.5 0.0 5e-16 58.8 0.0 4.5 4 0 0 4 4 4 4 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 CEP09244.1 - 1.1e-37 129.9 6.2 1.1e-37 129.9 6.2 3.2 3 1 0 3 3 3 1 Anticodon binding domain of tRNAs RWD PF05773.22 CEP09244.1 - 3.5e-17 62.7 0.1 3.5e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 CEP09244.1 - 7.2e-13 48.5 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.23 CEP09244.1 - 2.2e-05 24.5 0.0 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEP09244.1 - 0.001 18.8 1.2 0.43 10.2 0.4 3.1 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 LuxC PF05893.14 CEP09244.1 - 0.0078 15.3 0.3 0.019 14.0 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HGTP_anticodon PF03129.20 CEP09244.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.3 2 0 0 2 2 2 0 Anticodon binding domain Peptidase_M13 PF01431.21 CEP09245.1 - 2.3e-54 184.1 0.8 4e-54 183.3 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CEP09245.1 - 4.6e-27 95.7 3.0 2.4e-26 93.3 3.0 2.0 1 1 0 1 1 1 1 Peptidase family M13 DALR_1 PF05746.15 CEP09245.1 - 0.049 13.8 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 DALR anticodon binding domain adh_short PF00106.25 CEP09246.1 - 3.4e-28 98.5 0.0 8.9e-24 84.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEP09246.1 - 5.4e-15 55.6 0.0 2.9e-13 49.9 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP09246.1 - 1.9e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CEP09246.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CEP09246.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CEP09246.1 - 0.068 13.2 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TYW3 PF02676.14 CEP09248.1 - 1.7e-26 93.0 0.0 1.8e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 FOXP-CC PF16159.5 CEP09249.1 - 0.0056 17.3 0.7 0.0056 17.3 0.7 2.5 1 1 1 2 2 2 1 FOXP coiled-coil domain CNDH2_C PF16858.5 CEP09249.1 - 0.021 14.7 8.8 0.032 14.1 8.8 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3584 PF12128.8 CEP09249.1 - 0.067 10.7 10.7 0.089 10.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TAF1D PF15333.6 CEP09249.1 - 0.079 12.7 5.5 0.17 11.6 5.5 1.6 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D MCM_bind PF09739.9 CEP09249.1 - 0.14 10.6 9.2 0.26 9.7 9.2 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor zf-C2H2 PF00096.26 CEP09249.1 - 0.19 12.3 0.8 0.38 11.3 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2229 PF09989.9 CEP09249.1 - 0.45 10.1 3.4 0.66 9.6 2.5 1.7 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4407 PF14362.6 CEP09249.1 - 1 8.6 7.8 2 7.7 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 CEP09249.1 - 7.6 6.9 23.3 2.9 8.2 20.4 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CPSF100_C PF13299.6 CEP09249.1 - 7.7 6.7 7.8 2 8.6 4.3 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ank_2 PF12796.7 CEP09250.1 - 1e-41 141.4 5.2 1.3e-18 67.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEP09250.1 - 2.7e-39 132.7 5.8 5.9e-09 36.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP09250.1 - 7.8e-35 118.8 10.1 2.3e-14 53.6 0.2 4.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP09250.1 - 2.6e-34 113.4 3.1 1.3e-05 25.1 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CEP09250.1 - 1.1e-32 111.1 6.1 1.1e-05 25.6 0.1 6.0 6 0 0 6 6 6 5 Ankyrin repeat UL42 PF17638.2 CEP09251.1 - 0.043 13.8 1.0 0.073 13.1 1.0 1.4 1 0 0 1 1 1 0 HCMV UL42 zf-RING_2 PF13639.6 CEP09252.1 - 4.4e-13 49.3 5.0 8.6e-13 48.4 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP09252.1 - 1.3e-10 40.9 5.1 2.5e-10 40.0 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP09252.1 - 9.9e-10 38.6 3.8 9.9e-10 38.6 3.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEP09252.1 - 4.8e-09 35.8 2.5 9.8e-09 34.8 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEP09252.1 - 1.7e-08 34.2 4.8 3e-08 33.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP09252.1 - 2.6e-08 33.7 4.0 4.2e-08 33.0 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP09252.1 - 1.7e-05 24.7 1.3 4.3e-05 23.5 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEP09252.1 - 2.5e-05 24.2 2.5 6.5e-05 22.9 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP09252.1 - 5.9e-05 22.8 2.7 9.4e-05 22.2 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEP09252.1 - 0.0023 17.5 3.4 0.0042 16.7 3.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEP09252.1 - 0.0032 17.3 5.1 0.0063 16.4 5.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 CEP09252.1 - 0.0044 16.9 1.5 0.0085 16.0 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CEP09252.1 - 0.021 14.6 4.2 0.035 13.9 4.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CEP09252.1 - 0.028 14.5 6.5 0.057 13.5 6.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CEP09252.1 - 0.039 13.8 6.6 0.12 12.2 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 CEP09252.1 - 0.11 12.6 2.8 0.24 11.5 2.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger DUF1272 PF06906.11 CEP09252.1 - 0.34 11.0 1.9 0.66 10.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 CEP09252.1 - 0.5 10.6 6.0 9.8 6.4 6.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CEP09252.1 - 0.5 10.7 6.8 1.3 9.4 6.8 1.7 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 CEP09252.1 - 0.83 9.6 6.2 1.5 8.7 6.2 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CEP09252.1 - 1.9 8.7 4.6 5.3 7.3 4.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain REV PF00424.18 CEP09252.1 - 4.3 7.4 19.2 0.93 9.6 3.1 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) KI67R PF08065.12 CEP09252.1 - 9.7 6.8 13.3 0.66 10.5 6.6 2.3 2 0 0 2 2 2 0 KI67R (NUC007) repeat Lzipper-MIP1 PF14389.6 CEP09253.1 - 0.98 9.8 7.1 0.81 10.0 3.9 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Response_reg PF00072.24 CEP09254.1 - 1.3e-20 73.6 0.1 7.8e-14 51.8 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain Ribosomal_S8e PF01201.22 CEP09255.1 - 8.5e-42 142.6 5.0 8.5e-42 142.6 5.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S8e BTB_2 PF02214.22 CEP09255.1 - 8.2e-20 71.0 0.0 3.1e-19 69.1 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CEP09255.1 - 0.021 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain tRNA-synt_1 PF00133.22 CEP09256.1 - 5.1e-141 470.9 0.8 6.4e-141 470.6 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEP09256.1 - 2.2e-29 102.4 3.8 4.9e-29 101.2 3.8 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CEP09256.1 - 3e-05 23.6 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CEP09256.1 - 6.5e-05 21.8 5.0 0.0041 15.9 0.4 3.6 4 0 0 4 4 4 2 tRNA synthetases class I (M) RecR PF02132.15 CEP09256.1 - 0.031 13.8 1.3 0.074 12.6 1.3 1.7 1 0 0 1 1 1 0 RecR protein zf-FPG_IleRS PF06827.14 CEP09256.1 - 0.088 12.7 9.0 0.84 9.6 9.0 2.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS HHH_2 PF12826.7 CEP09256.1 - 0.18 11.9 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif MFS_1 PF07690.16 CEP09257.1 - 4.1e-33 114.8 43.8 2.5e-21 76.0 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP09257.1 - 4.6e-06 25.8 38.3 0.00089 18.2 38.4 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter AAA_23 PF13476.6 CEP09258.1 - 1e-20 75.1 0.3 1e-20 75.1 0.3 6.4 2 2 2 5 5 1 1 AAA domain SMC_N PF02463.19 CEP09258.1 - 7.8e-17 61.4 24.0 6.2e-15 55.2 24.0 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CEP09258.1 - 3.1e-07 30.5 17.6 3.1e-07 30.5 17.6 3.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 CEP09258.1 - 4.5e-05 23.1 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Metalloenzyme PF01676.18 CEP09258.1 - 0.0021 17.5 0.0 0.0039 16.6 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Nup54_57_C PF18570.1 CEP09258.1 - 0.0035 16.9 0.0 0.016 14.8 0.0 2.1 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain GAS PF13851.6 CEP09258.1 - 0.0038 16.6 23.4 0.0038 16.6 23.4 6.3 3 2 2 6 6 5 1 Growth-arrest specific micro-tubule binding AAA_21 PF13304.6 CEP09258.1 - 0.0068 16.3 0.1 0.0068 16.3 0.1 3.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Trimer_CC PF08954.11 CEP09258.1 - 0.043 13.4 11.6 0.62 9.7 0.2 4.1 4 0 0 4 4 4 0 Trimerisation motif AAA PF00004.29 CEP09258.1 - 0.2 12.0 1.6 0.55 10.7 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CEP09258.1 - 0.43 10.1 2.8 1.2 8.7 0.0 3.1 4 0 0 4 4 4 0 AAA domain RAB3GAP2_N PF14655.6 CEP09259.1 - 0.025 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Trypan_PARP PF05887.11 CEP09259.1 - 3.4 7.7 7.2 0.46 10.5 2.5 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) LRR_4 PF12799.7 CEP09260.1 - 0.018 15.5 9.6 1.2 9.7 0.0 5.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Peptidase_S26 PF10502.9 CEP09261.1 - 0.0019 18.0 0.0 0.62 9.8 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CEP09261.1 - 0.0039 17.1 0.1 0.0078 16.1 0.1 1.6 1 1 0 1 1 1 1 Peptidase S24-like LRR_8 PF13855.6 CEP09262.1 - 7.3e-27 92.9 38.3 1.8e-09 37.2 5.3 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEP09262.1 - 9.5e-19 67.2 14.9 4.9e-06 26.8 0.2 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Ribosomal_L9_C PF03948.14 CEP09262.1 - 6e-13 49.1 0.7 1.8e-12 47.6 0.7 1.9 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 CEP09262.1 - 4.8e-11 42.0 0.1 8.9e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain LRR_1 PF00560.33 CEP09262.1 - 8.7e-05 22.6 22.1 2.9 8.8 0.0 8.0 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 CEP09262.1 - 0.0015 18.4 22.2 4.4 7.6 0.3 7.0 7 0 0 7 7 7 3 Leucine Rich repeat NOA36 PF06524.12 CEP09264.1 - 0.22 10.8 5.3 0.37 10.1 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 CEP09264.1 - 7.8 6.2 9.0 15 5.3 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Mito_carr PF00153.27 CEP09265.1 - 4.6e-28 97.0 5.1 1.6e-12 47.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP09265.1 - 0.018 14.2 0.2 0.079 12.1 0.0 2.1 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Bacteriocin_IIc PF10439.9 CEP09265.1 - 0.39 10.9 8.5 7.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Sec10 PF07393.11 CEP09266.1 - 4.8e-111 372.4 3.4 6.2e-111 372.0 3.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 CEP09266.1 - 6.2e-07 29.2 0.1 1.4e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP09266.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Cyclin PF08613.11 CEP09267.1 - 7.3e-39 133.7 0.8 1.2e-38 133.1 0.8 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP09267.1 - 0.072 12.8 0.2 0.072 12.8 0.2 1.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF1635 PF07795.11 CEP09267.1 - 0.26 11.1 4.3 0.11 12.4 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PIH1 PF08190.12 CEP09268.1 - 8.5e-18 64.4 0.0 1.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 PIH1 N-terminal domain zf-MYND PF01753.18 CEP09269.1 - 6.7e-08 32.5 12.9 1.4e-07 31.5 12.9 1.6 1 0 0 1 1 1 1 MYND finger TPR_17 PF13431.6 CEP09269.1 - 2.2e-05 24.5 0.2 0.0021 18.3 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP09269.1 - 0.00019 21.8 0.4 18 6.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP09269.1 - 0.00022 20.9 10.5 0.00061 19.5 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09269.1 - 0.00023 21.1 13.6 0.14 12.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP09269.1 - 0.00032 20.6 11.3 0.043 13.9 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP09269.1 - 0.0012 18.4 0.1 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 CEP09269.1 - 0.0022 18.7 0.1 0.37 11.7 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP09269.1 - 0.013 16.2 0.1 0.32 11.7 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3837 PF12939.7 CEP09269.1 - 0.024 15.0 2.5 0.1 13.0 2.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3837) TPR_9 PF13371.6 CEP09269.1 - 0.057 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP09269.1 - 0.098 13.0 1.7 4.9 7.5 0.2 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat ORC5_C PF14630.6 CEP09270.1 - 5.1e-73 246.1 0.0 6.9e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CEP09270.1 - 1.9e-12 47.9 0.0 4.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP09270.1 - 1.9e-06 28.2 0.0 4.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP09270.1 - 2.1e-05 24.3 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEP09270.1 - 0.00057 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CEP09270.1 - 0.00061 19.8 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 CEP09270.1 - 0.0033 17.8 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEP09270.1 - 0.0041 17.2 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CEP09270.1 - 0.06 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 CEP09270.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CEP09270.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein RuvB_N PF05496.12 CEP09270.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ubiquitin PF00240.23 CEP09271.1 - 2.1e-33 113.9 0.6 2.8e-33 113.5 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CEP09271.1 - 7.2e-31 105.8 12.1 1.1e-30 105.2 12.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CEP09271.1 - 8.6e-15 54.3 0.7 1.3e-14 53.7 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEP09271.1 - 5.1e-05 23.6 0.2 0.00018 21.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CEP09271.1 - 0.0079 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEP09271.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CEP09271.1 - 0.026 15.1 0.1 0.031 14.8 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP09271.1 - 0.038 14.1 0.0 0.076 13.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CEP09271.1 - 0.04 14.0 1.1 8.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain TYW3 PF02676.14 CEP09272.1 - 1.4e-49 168.4 0.0 2e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Ras PF00071.22 CEP09272.1 - 1.1e-47 161.7 0.0 2.2e-47 160.7 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CEP09272.1 - 2.1e-28 98.9 0.0 5.4e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP09272.1 - 1.4e-09 37.7 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP09272.1 - 0.0073 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP09272.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CEP09272.1 - 0.012 15.9 0.4 0.097 13.1 0.1 2.5 2 1 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 CEP09272.1 - 0.043 13.3 1.2 0.13 11.7 0.2 2.0 1 1 1 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 CEP09272.1 - 0.06 13.7 0.3 0.16 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CEP09272.1 - 0.071 12.6 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CEP09272.1 - 0.075 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein TsaE PF02367.17 CEP09272.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CEP09272.1 - 0.11 12.4 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Aconitase_C PF00694.19 CEP09272.1 - 0.19 12.0 0.2 0.42 10.9 0.2 1.5 1 0 0 1 1 1 0 Aconitase C-terminal domain CKAP2_C PF15297.6 CEP09273.1 - 0.00042 19.5 10.7 0.00071 18.8 10.7 1.3 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus Spc7 PF08317.11 CEP09273.1 - 0.017 14.0 13.6 0.029 13.3 13.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Zn_Tnp_IS1595 PF12760.7 CEP09273.1 - 0.06 13.3 5.0 0.72 9.9 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3450 PF11932.8 CEP09273.1 - 0.12 11.6 9.8 0.24 10.7 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 CEP09273.1 - 0.29 10.9 11.8 0.78 9.6 11.8 1.8 1 0 0 1 1 1 0 Septum formation initiator LMBR1 PF04791.16 CEP09273.1 - 0.65 8.8 4.7 1.1 8.1 4.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein LicD PF04991.13 CEP09273.1 - 1.5 8.9 9.2 0.23 11.5 5.1 1.7 2 0 0 2 2 2 0 LicD family USP8_interact PF08941.10 CEP09273.1 - 2.6 7.8 7.0 5.9 6.7 7.0 1.6 1 0 0 1 1 1 0 USP8 interacting FapA PF03961.13 CEP09273.1 - 4.4 5.8 12.8 6.9 5.1 12.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CEP09273.1 - 7.5 5.7 12.6 14 4.9 12.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein RNase_H PF00075.24 CEP09274.1 - 0.0021 18.2 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 RNase H La PF05383.17 CEP09275.1 - 5.4e-25 87.2 0.0 1.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CEP09275.1 - 6.2e-07 29.2 0.4 1.4e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plk4_PB1 PF18190.1 CEP09275.1 - 0.012 15.8 0.8 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Seryl_tRNA_N PF02403.22 CEP09275.1 - 0.014 15.6 2.2 0.014 15.6 2.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Zn_clus PF00172.18 CEP09276.1 - 8.4e-05 22.6 13.8 0.00016 21.7 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4611 PF15387.6 CEP09276.1 - 0.0085 16.3 1.3 0.0085 16.3 1.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4611) Nefa_Nip30_N PF10187.9 CEP09277.1 - 4.8e-18 65.4 16.5 4.8e-18 65.4 16.5 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 CEP09277.1 - 0.082 12.5 20.3 0.11 12.2 20.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3492 PF11997.8 CEP09277.1 - 1 9.0 7.9 0.37 10.5 5.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) ALMT PF11744.8 CEP09277.1 - 1.1 8.1 10.3 1.3 7.8 10.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CpxA_peri PF16527.5 CEP09277.1 - 7.4 6.9 8.9 2.1 8.7 3.4 2.5 1 1 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain RRM_1 PF00076.22 CEP09278.1 - 5.7e-09 35.7 0.8 0.0043 16.8 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP09278.1 - 7e-08 32.3 0.4 0.0026 17.7 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 CEP09278.1 - 2.1e-05 24.7 0.1 5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 PWI domain zf-CCCH PF00642.24 CEP09278.1 - 6.1e-05 22.8 1.6 0.00012 21.8 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP09278.1 - 0.00037 20.5 2.2 0.00084 19.3 2.2 1.7 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 CEP09278.1 - 0.05 13.7 13.2 0.24 11.5 0.0 3.8 4 0 0 4 4 4 0 RNA binding motif CpxA_peri PF16527.5 CEP09278.1 - 0.21 12.0 2.4 0.62 10.4 2.4 1.7 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain DDHD PF02862.17 CEP09278.1 - 0.23 11.6 7.9 0.41 10.8 3.2 2.3 2 0 0 2 2 2 0 DDHD domain zf-CCCH_2 PF14608.6 CEP09278.1 - 0.43 11.1 2.6 0.76 10.3 2.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEP09278.1 - 3 8.6 6.3 0.65 10.7 0.4 2.6 2 0 0 2 2 2 0 Torus domain DUF4407 PF14362.6 CEP09278.1 - 4 6.7 11.5 7.9 5.7 11.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CEP09278.1 - 8.7 5.8 15.0 2.4 7.7 12.0 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1077 PF06417.12 CEP09279.1 - 3.1e-35 120.8 4.2 3.6e-35 120.5 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ERGIC_N PF13850.6 CEP09279.1 - 0.0069 16.7 0.9 0.0096 16.3 0.9 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IRK PF01007.20 CEP09280.1 - 0.4 10.5 6.5 0.24 11.2 0.7 2.3 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain MAPEG PF01124.18 CEP09280.1 - 0.67 9.9 13.0 2.5 8.0 13.0 1.9 1 1 0 1 1 1 0 MAPEG family DUF1218 PF06749.12 CEP09280.1 - 9.7 6.8 9.7 0.18 12.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DEAD PF00270.29 CEP09281.1 - 4.9e-28 98.1 0.0 1.3e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP09281.1 - 3.1e-16 59.7 0.1 6.1e-15 55.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 CEP09281.1 - 7.3e-09 36.3 0.5 2.3e-08 34.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) ResIII PF04851.15 CEP09281.1 - 6.8e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CEP09281.1 - 0.24 11.7 1.2 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 DNA replication factor CDT1 like DUF1344 PF07076.11 CEP09282.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Med19 PF10278.9 CEP09283.1 - 0.033 14.1 17.6 4 7.3 0.0 2.7 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.11 CEP09283.1 - 7.2 6.6 18.0 11 6.1 18.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sec61_beta PF03911.16 CEP09284.1 - 0.014 15.4 1.6 0.031 14.3 1.6 1.6 1 0 0 1 1 1 0 Sec61beta family SCO1-SenC PF02630.14 CEP09285.1 - 1.2e-43 148.3 0.1 2e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CEP09285.1 - 0.0033 17.4 0.0 0.0073 16.2 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CEP09285.1 - 0.0041 17.4 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Caskin-Pro-rich PF16907.5 CEP09285.1 - 0.18 12.4 1.9 0.33 11.5 1.9 1.4 1 0 0 1 1 1 0 Proline rich region of Caskin proteins RhoGAP PF00620.27 CEP09286.1 - 4.1e-36 124.1 0.0 5.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain PseudoU_synth_2 PF00849.22 CEP09287.1 - 3.9e-30 105.0 0.1 4.8e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase ACC_central PF08326.12 CEP09288.1 - 5.8e-250 831.5 3.6 7.2e-250 831.2 3.6 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CEP09288.1 - 2.1e-175 584.1 0.0 2.9e-175 583.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CEP09288.1 - 8.9e-55 185.5 0.0 2e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEP09288.1 - 2.2e-28 99.0 0.1 5.5e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP09288.1 - 1.1e-21 76.9 0.0 7.3e-21 74.3 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEP09288.1 - 3.6e-15 55.5 0.0 7.8e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 CEP09288.1 - 0.00018 21.6 0.0 0.0006 19.9 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CEP09288.1 - 0.0013 18.3 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEP09288.1 - 0.0029 17.4 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CEP09288.1 - 0.041 13.4 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CEP09288.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 CEP09288.1 - 0.065 12.8 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Gp-FAR-1 PF05823.12 CEP09288.1 - 2.6 8.4 5.2 3.7 7.9 0.5 3.2 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HTH_Tnp_Tc3_2 PF01498.18 CEP09290.1 - 4.9e-15 55.5 0.5 1e-14 54.5 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP09290.1 - 0.00027 21.5 0.1 0.00052 20.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain zf-C2H2 PF00096.26 CEP09291.1 - 0.03 14.8 1.5 0.03 14.8 1.5 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2110 PF09883.9 CEP09291.1 - 0.032 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Robl_LC7 PF03259.17 CEP09291.1 - 0.15 11.8 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain Ribosomal_60s PF00428.19 CEP09291.1 - 0.19 12.3 3.7 0.58 10.8 3.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein MULE PF10551.9 CEP09293.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.9 1 0 0 1 1 1 0 MULE transposase domain GATA PF00320.27 CEP09295.1 - 5.3e-29 99.5 19.7 1.2e-14 53.7 7.3 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP09295.1 - 0.0043 16.5 4.6 0.14 11.7 0.5 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding TDP43_N PF18694.1 CEP09295.1 - 0.024 14.5 0.2 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain OrfB_Zn_ribbon PF07282.11 CEP09295.1 - 0.035 14.0 0.3 0.035 14.0 0.3 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 CEP09295.1 - 0.17 12.1 5.6 0.76 9.9 0.7 2.9 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 CEP09295.1 - 0.3 11.3 7.7 0.43 10.8 0.8 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CEP09295.1 - 1.7 8.6 7.0 3.3 7.6 1.0 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cytochrome_C554 PF13435.6 CEP09295.1 - 3.1 8.8 11.2 2.3 9.2 0.3 3.2 3 0 0 3 3 3 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.6 CEP09295.1 - 8.4 6.9 14.4 0.29 11.6 1.6 3.1 2 1 0 2 2 2 0 Cytochrome c3 TpcC PF12642.7 CEP09296.1 - 0.12 12.2 0.5 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Conjugative transposon protein TcpC zf-C3HC4_3 PF13920.6 CEP09297.1 - 5.3e-09 35.8 5.5 9.6e-09 35.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 CEP09297.1 - 1.1e-07 31.5 1.5 2.3e-07 30.5 1.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 CEP09297.1 - 4.1e-07 29.7 9.0 7.7e-07 28.9 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP09297.1 - 7.3e-07 29.1 9.6 1.6e-06 28.0 9.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP09297.1 - 1.9e-06 27.7 9.4 3.4e-06 26.9 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEP09297.1 - 3.8e-06 26.7 10.0 7.9e-06 25.6 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP09297.1 - 1.2e-05 25.6 7.8 2.2e-05 24.7 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RanBP PF00641.18 CEP09297.1 - 2.9e-05 23.3 2.3 7.5e-05 22.0 2.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf_CCCH_4 PF18345.1 CEP09297.1 - 4e-05 23.5 2.5 8e-05 22.6 2.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 CEP09297.1 - 8.7e-05 22.6 8.1 0.00022 21.3 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 CEP09297.1 - 0.00012 22.2 3.9 0.00012 22.2 3.9 1.6 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CEP09297.1 - 0.0033 17.3 6.8 0.0061 16.4 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 CEP09297.1 - 0.021 14.7 1.7 0.045 13.6 1.7 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger zf-Nse PF11789.8 CEP09297.1 - 0.057 13.2 2.4 0.11 12.3 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 CEP09297.1 - 0.3 10.8 2.5 0.62 9.8 2.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_L34e PF01199.18 CEP09297.1 - 1.9 8.8 6.1 0.27 11.6 1.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L34e Abhydrolase_1 PF00561.20 CEP09299.1 - 2.2e-48 165.1 0.0 6.7e-47 160.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CEP09299.1 - 0.00096 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CEP09299.1 - 0.0015 17.8 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 GAS2 PF02187.17 CEP09300.1 - 1e-11 44.7 0.0 3.1e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain POX PF07526.11 CEP09300.1 - 0.063 13.8 2.7 7.2 7.2 0.1 4.1 3 0 0 3 3 3 0 Associated with HOX DUF4132 PF13569.6 CEP09300.1 - 0.4 10.5 4.3 12 5.6 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) DUF1043 PF06295.12 CEP09300.1 - 0.88 9.6 3.8 4.4 7.3 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1043) CitMHS PF03600.16 CEP09302.1 - 2.7e-20 72.8 16.4 2.7e-20 72.8 16.4 2.6 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.15 CEP09302.1 - 1.1e-18 67.9 26.9 3.8e-10 39.7 4.4 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Homeobox_KN PF05920.11 CEP09303.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain NOA36 PF06524.12 CEP09303.1 - 2.9 7.1 7.6 3.7 6.8 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_49 PF13896.6 CEP09305.1 - 3.6e-25 89.0 0.1 7.3e-19 68.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Lipocalin_9 PF17186.4 CEP09305.1 - 0.018 15.3 0.3 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Lipocalin-like domain SUIM_assoc PF16619.5 CEP09305.1 - 0.33 11.0 7.5 1.5 8.9 7.7 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NOA36 PF06524.12 CEP09307.1 - 0.32 10.3 10.9 0.33 10.2 10.9 1.1 1 0 0 1 1 1 0 NOA36 protein Velvet PF11754.8 CEP09308.1 - 6.2e-55 186.9 1.2 8e-27 94.8 0.1 2.5 1 1 1 2 2 2 2 Velvet factor tRNA-synt_2b PF00587.25 CEP09308.1 - 7.4e-37 127.0 0.0 1.7e-36 125.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEP09308.1 - 9.2e-18 64.2 0.2 1.8e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CEP09308.1 - 6.5e-14 51.7 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CEP09308.1 - 7.1e-13 48.4 0.0 2.3e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 TGS domain Velvet PF11754.8 CEP09309.1 - 3e-62 210.8 11.0 9.1e-62 209.2 1.1 3.0 2 1 0 2 2 2 1 Velvet factor START PF01852.19 CEP09310.1 - 2.3e-11 43.5 0.0 3.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 START domain RabGAP-TBC PF00566.18 CEP09311.1 - 3.6e-53 180.4 0.1 3.6e-53 180.4 0.1 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain TSC22 PF01166.18 CEP09311.1 - 4.1 7.8 20.7 0.046 14.0 3.1 4.8 3 2 1 4 4 4 0 TSC-22/dip/bun family zf-RING_5 PF14634.6 CEP09312.1 - 7.9 6.5 13.8 0.2 11.6 4.0 2.8 3 0 0 3 3 3 0 zinc-RING finger domain Sel1 PF08238.12 CEP09313.1 - 2.6e-41 139.1 20.1 2.3e-08 34.4 0.0 7.9 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 CEP09313.1 - 0.0022 18.5 1.8 0.15 12.8 0.2 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP09313.1 - 0.47 10.4 0.1 0.47 10.4 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09313.1 - 0.53 10.6 4.9 15 6.1 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEP09313.1 - 0.99 9.6 4.7 1.7 8.9 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 CEP09314.1 - 6.4e-49 166.8 0.1 7.5e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP09314.1 - 9.3e-18 64.5 0.4 2.4e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP09314.1 - 4.1e-16 59.3 0.2 1.1e-13 51.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP09314.1 - 1.6e-05 24.2 5.7 0.018 14.1 0.3 4.2 3 2 2 5 5 5 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CEP09314.1 - 7e-05 22.1 3.1 0.0033 16.6 0.1 2.8 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 CEP09314.1 - 0.00013 21.7 0.6 0.41 10.2 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 CEP09314.1 - 0.00019 20.8 0.0 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CEP09314.1 - 0.00052 20.2 0.4 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CEP09314.1 - 0.0015 17.9 0.0 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEP09314.1 - 0.0019 17.5 0.2 0.1 11.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CEP09314.1 - 0.0031 17.9 0.0 0.57 10.6 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 CEP09314.1 - 0.0042 15.8 0.2 0.053 12.2 0.2 2.7 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 CEP09314.1 - 0.011 14.8 0.3 0.36 9.9 0.1 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CEP09314.1 - 0.04 12.8 0.1 0.99 8.2 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CEP09314.1 - 0.086 12.8 0.2 13 5.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FMO-like PF00743.19 CEP09314.1 - 0.1 11.0 0.0 0.26 9.7 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Na_H_Exchanger PF00999.21 CEP09315.1 - 1.1e-55 189.0 39.7 1.7e-55 188.4 39.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_2 PF00890.24 CEP09316.1 - 7.4e-82 275.7 2.4 8.4e-82 275.5 2.4 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEP09316.1 - 1e-13 51.6 1.6 2.9e-08 33.7 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEP09316.1 - 2.7e-08 33.6 4.9 2.6e-07 30.3 4.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEP09316.1 - 4.8e-08 33.1 0.4 1.1e-06 28.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEP09316.1 - 5.4e-08 31.9 4.1 1.1e-05 24.4 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 CEP09316.1 - 3.4e-07 29.7 8.6 0.00026 20.2 0.3 3.2 3 0 0 3 3 3 3 Glucose inhibited division protein A Thi4 PF01946.17 CEP09316.1 - 3.5e-07 29.7 2.1 0.00041 19.7 0.0 3.0 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 CEP09316.1 - 7e-07 28.8 3.7 1.2e-06 28.0 1.7 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEP09316.1 - 0.0071 15.6 0.3 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 CEP09316.1 - 0.0081 15.5 0.1 0.02 14.2 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CEP09316.1 - 0.0099 15.2 1.0 0.0099 15.2 1.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CEP09316.1 - 0.012 14.9 0.3 2.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CEP09316.1 - 0.013 16.1 2.6 0.057 14.0 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CEP09316.1 - 0.013 14.9 0.3 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 CEP09316.1 - 0.02 14.9 1.7 3.5 7.6 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding KOW PF00467.29 CEP09316.1 - 0.055 13.5 4.8 2.3 8.3 0.1 3.3 3 0 0 3 3 2 0 KOW motif Lycopene_cycl PF05834.12 CEP09316.1 - 0.099 11.7 1.7 0.11 11.6 0.3 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 CEP09316.1 - 0.15 10.9 0.6 0.24 10.2 0.6 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.24 CEP09317.1 - 1.1e-53 183.2 0.0 4.5e-53 181.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP09317.1 - 7.3e-09 35.7 0.0 2.2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP09317.1 - 0.049 12.9 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP09317.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5390 PF17365.2 CEP09320.1 - 0.01 16.1 0.9 0.017 15.4 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5390) zf-C2H2_6 PF13912.6 CEP09324.1 - 0.023 14.7 0.3 0.049 13.7 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger PT PF04886.12 CEP09325.1 - 2.2 7.9 7.0 3.3 7.3 1.2 2.9 2 0 0 2 2 2 0 PT repeat DUF4065 PF13274.6 CEP09326.1 - 0.01 16.7 0.2 0.014 16.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) LETM1 PF07766.13 CEP09326.1 - 0.018 14.4 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 LETM1-like protein Integrase_H2C2 PF17921.1 CEP09326.1 - 0.022 14.9 0.1 0.05 13.7 0.1 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Integrase_H2C2 PF17921.1 CEP09327.1 - 9.1e-21 73.7 0.1 1.4e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CEP09327.1 - 5.4e-10 39.5 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP09327.1 - 0.16 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CEP09328.1 - 8.5e-17 61.4 0.0 1.3e-16 60.9 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Acyl_CoA_thio PF02551.15 CEP09328.1 - 0.054 13.3 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Acyl-CoA thioesterase Chromo PF00385.24 CEP09329.1 - 0.0016 18.3 0.2 0.0026 17.6 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 CEP09330.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2034 PF10356.9 CEP09333.1 - 6.6e-20 71.3 5.3 3.7e-10 39.5 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CEP09333.1 - 4.2e-07 30.0 0.0 6.7e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Restriction endonuclease PNP_UDP_1 PF01048.20 CEP09334.1 - 5.1e-25 88.1 0.0 6.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily GDP_Man_Dehyd PF16363.5 CEP09335.1 - 4.5e-162 539.1 0.0 5.1e-162 538.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP09335.1 - 6.3e-75 251.7 0.0 7.7e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEP09335.1 - 1.6e-07 30.7 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEP09335.1 - 6.5e-05 22.2 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CEP09335.1 - 7e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CEP09335.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding TFIIB PF00382.19 CEP09336.1 - 2.8e-45 152.2 1.9 2.3e-24 85.2 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CEP09336.1 - 1.4e-14 53.3 1.0 2.3e-14 52.6 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 CEP09336.1 - 0.0003 20.8 1.3 0.00054 20.0 1.3 1.5 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 CEP09336.1 - 0.00056 20.0 0.2 0.07 13.2 0.1 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CEP09336.1 - 0.0057 16.4 0.9 0.24 11.2 0.4 2.1 1 1 1 2 2 2 2 Cyclin, N-terminal domain PH PF00169.29 CEP09337.1 - 9.4e-15 55.0 0.1 3e-14 53.4 0.1 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEP09337.1 - 2.1e-05 24.9 0.8 0.0011 19.4 0.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CEP09337.1 - 0.17 12.2 0.0 0.64 10.4 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain WW PF00397.26 CEP09338.1 - 0.15 12.1 1.2 4.4 7.5 0.1 2.8 2 0 0 2 2 2 0 WW domain Lipase_GDSL_2 PF13472.6 CEP09339.1 - 6.1e-07 30.0 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEP09339.1 - 0.00042 20.4 0.3 0.00094 19.2 0.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 CEP09339.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal SASA PF03629.18 CEP09339.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase ATP-synt_S1 PF05827.12 CEP09340.1 - 8.4e-05 22.4 0.1 0.00018 21.4 0.1 1.5 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) GIDA PF01134.22 CEP09342.1 - 3e-153 510.6 0.0 3.8e-153 510.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CEP09342.1 - 1.9e-57 194.8 0.1 5.3e-43 147.7 0.0 2.4 1 1 1 2 2 2 2 GidA associated domain FAD_oxidored PF12831.7 CEP09342.1 - 7.7e-07 28.8 0.1 1.3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP09342.1 - 4.9e-06 26.0 1.2 6.4e-05 22.3 1.1 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEP09342.1 - 0.00011 21.4 1.1 0.00011 21.4 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CEP09342.1 - 0.00029 19.7 2.1 0.0074 15.0 0.4 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CEP09342.1 - 0.00056 19.3 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CEP09342.1 - 0.11 11.8 0.1 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP09342.1 - 0.15 12.1 0.3 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEP09342.1 - 0.19 12.0 0.6 0.54 10.5 0.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 CEP09343.1 - 3.3e-67 226.4 0.0 1.5e-66 224.3 0.0 1.7 1 1 1 2 2 2 1 ThiF family E2_bind PF08825.10 CEP09343.1 - 5.1e-28 97.0 0.0 8.9e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 CEP09343.1 - 0.00082 19.5 0.3 0.0017 18.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 CEP09343.1 - 0.021 15.0 0.8 0.057 13.6 0.8 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 CEP09343.1 - 0.055 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 CEP09343.1 - 0.096 13.3 0.1 0.39 11.4 0.1 2.2 2 0 0 2 2 2 0 PglD N-terminal domain UAE_UbL PF14732.6 CEP09343.1 - 0.11 13.1 0.0 0.37 11.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 CEP09343.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding UTP15_C PF09384.10 CEP09344.1 - 0.00016 21.4 0.4 0.0097 15.6 0.1 2.5 2 0 0 2 2 2 2 UTP15 C terminal DUF3666 PF12408.8 CEP09344.1 - 0.028 13.6 1.2 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase Utp12 PF04003.12 CEP09344.1 - 0.038 14.3 1.1 0.21 11.9 0.3 2.6 2 1 1 3 3 3 0 Dip2/Utp12 Family Fasciclin PF02469.22 CEP09345.1 - 2.3e-29 102.2 7.3 3.7e-18 66.0 2.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Adeno_E1B_55K PF01696.17 CEP09345.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen SpaA PF17802.1 CEP09345.1 - 0.11 12.8 1.3 0.34 11.3 1.3 1.8 1 0 0 1 1 1 0 Prealbumin-like fold domain Lambda_CIII PF02061.16 CEP09345.1 - 0.17 12.0 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Lambda Phage CIII Asn_synthase PF00733.21 CEP09346.1 - 2e-72 244.8 0.0 2.8e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CEP09346.1 - 2.1e-38 131.0 0.0 3.8e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEP09346.1 - 3.2e-30 105.1 0.0 5.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEP09346.1 - 0.0068 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein F-box-like PF12937.7 CEP09347.1 - 5.8e-09 35.7 0.4 1.2e-08 34.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP09347.1 - 1.8e-07 30.9 0.8 5.4e-07 29.3 0.8 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CEP09347.1 - 0.00056 19.8 0.6 0.0016 18.3 0.2 2.0 2 0 0 2 2 2 1 F-box Ssl1 PF04056.14 CEP09348.1 - 3.8e-83 278.0 0.0 4.9e-83 277.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CEP09348.1 - 2.8e-13 49.9 13.0 2.8e-13 49.9 13.0 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CEP09348.1 - 6.1e-12 46.1 0.0 1.3e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 CEP09348.1 - 0.00011 21.8 1.1 0.00018 21.1 1.1 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.28 CEP09348.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain IBR PF01485.21 CEP09348.1 - 2.3 8.5 20.3 0.38 11.0 11.6 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain RNA_lig_T4_1 PF09511.10 CEP09349.1 - 2.5e-71 240.0 0.7 3.7e-71 239.5 0.7 1.2 1 0 0 1 1 1 1 RNA ligase DENN PF02141.21 CEP09349.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 DENN (AEX-3) domain Peptidase_S9 PF00326.21 CEP09350.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DDE_3 PF13358.6 CEP09351.1 - 3.8e-09 36.5 0.5 1.6e-08 34.4 0.5 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP09351.1 - 0.0029 17.8 0.4 0.041 14.1 0.4 2.3 1 1 1 2 2 2 2 Transposase HTH_32 PF13565.6 CEP09351.1 - 0.018 15.7 0.0 0.048 14.3 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 CEP09351.1 - 0.018 14.9 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 HTH domain HCBP_related PF06594.11 CEP09351.1 - 1.4 8.9 7.1 0.11 12.4 0.7 2.4 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain PDDEXK_7 PF04411.12 CEP09352.1 - 0.036 14.1 4.0 0.071 13.1 3.4 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF3882 PF07066.11 CEP09352.1 - 0.076 13.1 0.2 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Lactococcus phage M3 protein FtsK_SpoIIIE_N PF12538.8 CEP09352.1 - 0.78 10.0 5.2 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 DNA transporter DDE_3 PF13358.6 CEP09353.1 - 7.3e-19 68.0 0.0 2.3e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease GET2 PF08690.10 CEP09353.1 - 9.5e-06 25.5 6.3 2.1e-05 24.4 6.3 1.5 1 0 0 1 1 1 1 GET complex subunit GET2 HTH_23 PF13384.6 CEP09353.1 - 0.2 11.5 2.3 0.23 11.3 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain CYYR1 PF10873.8 CEP09353.1 - 0.71 10.3 1.6 1.4 9.3 1.6 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 SRP54 PF00448.22 CEP09354.1 - 5.1e-49 166.6 0.1 1e-48 165.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CEP09354.1 - 1.4e-46 159.7 22.1 4.5e-46 158.1 22.1 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CEP09354.1 - 3.2e-11 43.3 0.0 2.9e-10 40.2 0.0 2.8 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CEP09354.1 - 9.3e-05 21.5 0.0 0.00031 19.8 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CEP09354.1 - 0.0028 17.4 0.0 0.0089 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP09354.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CEP09354.1 - 0.027 14.5 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEP09354.1 - 0.07 13.1 0.4 1.7 8.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain Fer4_NifH PF00142.18 CEP09354.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 CEP09354.1 - 0.099 12.5 0.1 2.1 8.2 0.1 2.7 1 1 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 CEP09354.1 - 0.14 12.2 2.7 0.54 10.4 0.6 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase DRY_EERY PF09750.9 CEP09356.1 - 3.1e-13 50.2 8.7 2.1e-12 47.5 0.0 4.2 3 1 0 3 3 3 1 Alternative splicing regulator Histone_HNS PF00816.21 CEP09356.1 - 0.026 15.3 0.3 0.026 15.3 0.3 2.6 2 0 0 2 2 2 0 H-NS histone family Seipin PF06775.14 CEP09357.1 - 4.9e-48 163.8 2.9 9e-48 163.0 2.9 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Haemocyan_bet_s PF14830.6 CEP09357.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich NDUFA12 PF05071.16 CEP09358.1 - 0.024 15.4 5.3 0.043 14.7 5.3 1.6 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 EZH2_WD-Binding PF11616.8 CEP09358.1 - 0.056 13.5 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 WD repeat binding protein EZH2 DDE_Tnp_1_7 PF13843.6 CEP09365.1 - 1.1e-45 156.5 0.0 1.3e-45 156.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_5 PF13546.6 CEP09365.1 - 0.037 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CEP09365.1 - 0.043 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 CEP09366.1 - 2.3e-13 50.2 1.3 6.5e-13 48.7 1.3 1.8 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP09366.1 - 3e-05 24.6 0.5 0.00073 20.1 0.2 2.5 2 0 0 2 2 2 1 Homeodomain-like domain DUF3268 PF11672.8 CEP09366.1 - 0.022 15.1 0.3 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain Prok-RING_1 PF14446.6 CEP09366.1 - 0.042 13.8 0.5 0.042 13.8 0.5 3.8 4 1 0 4 4 4 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 CEP09366.1 - 0.056 13.1 1.3 5.5 6.7 0.1 3.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Katanin_con80 PF13925.6 CEP09366.1 - 0.058 13.4 0.5 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 con80 domain of Katanin zf-C4_Topoisom PF01396.19 CEP09366.1 - 0.071 12.9 2.7 3.8 7.4 0.2 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CEP09366.1 - 0.3 11.3 15.5 0.6 10.3 0.3 4.3 4 0 0 4 4 4 0 Zinc knuckle zinc_ribbon_4 PF13717.6 CEP09366.1 - 0.33 10.9 3.7 4.8 7.2 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEP09366.1 - 0.63 10.1 9.4 1.7 8.6 1.2 3.8 3 1 0 3 3 3 0 zinc-ribbons zf-C2H2_10 PF16588.5 CEP09366.1 - 0.7 9.7 5.8 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 C2H2 zinc-finger zf-ribbon_3 PF13248.6 CEP09366.1 - 0.95 9.0 6.1 2.4 7.7 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_7 PF02591.15 CEP09366.1 - 1.6 9.0 5.5 1.3 9.3 0.5 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain PHD PF00628.29 CEP09366.1 - 1.6 8.7 9.2 14 5.7 0.2 3.8 4 0 0 4 4 4 0 PHD-finger zinc_ribbon_2 PF13240.6 CEP09366.1 - 4.7 7.1 8.8 3.7 7.4 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain AAA_assoc PF14363.6 CEP09367.1 - 0.048 14.0 0.1 0.06 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA ComFB PF10719.9 CEP09368.1 - 0.21 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Late competence development protein ComFB DUF2092 PF09865.9 CEP09369.1 - 0.068 12.5 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) zf-C2HC_2 PF13913.6 CEP09371.1 - 0.095 12.6 0.3 0.095 12.6 0.3 2.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type CENP-Q PF13094.6 CEP09371.1 - 0.45 10.7 16.3 0.042 14.0 6.7 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-Dof PF02701.15 CEP09371.1 - 0.59 10.3 4.7 0.26 11.5 0.9 2.5 2 0 0 2 2 2 0 Dof domain, zinc finger Zn_Tnp_IS1595 PF12760.7 CEP09371.1 - 0.62 10.1 6.2 1.9 8.6 0.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Striatin PF08232.12 CEP09371.1 - 1.6 9.3 27.2 0.088 13.4 9.0 2.8 3 0 0 3 3 3 0 Striatin family Vfa1 PF08432.10 CEP09371.1 - 4.9 7.5 30.3 8.8 6.6 11.8 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF4065 PF13274.6 CEP09371.1 - 8.2 7.4 12.4 29 5.6 6.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) LicD PF04991.13 CEP09371.1 - 8.2 6.5 16.6 6.7 6.8 6.6 2.5 2 0 0 2 2 2 0 LicD family Phage_integrase PF00589.22 CEP09372.1 - 0.0036 17.1 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family ErmC PF06308.11 CEP09372.1 - 0.065 13.6 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) ABM PF03992.16 CEP09372.1 - 0.099 12.8 0.0 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DNA_pol_A_exo1 PF01612.20 CEP09376.1 - 9.6e-07 28.7 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Helitron_like_N PF14214.6 CEP09378.1 - 7.4e-16 58.9 0.0 2.3e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.27 CEP09380.1 - 5e-36 124.3 0.0 8.4e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MLVIN_C PF18697.1 CEP09383.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain HAD PF12710.7 CEP09388.1 - 1.8e-17 64.3 0.0 2.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP09388.1 - 0.0019 18.5 0.0 0.0064 16.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP09388.1 - 0.0077 16.3 0.1 3 7.9 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CEP09388.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Kelch_5 PF13854.6 CEP09389.1 - 1e-17 63.7 3.3 3.9e-06 26.7 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 CEP09389.1 - 1.2e-15 57.4 13.7 2.9e-06 27.4 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP09389.1 - 4.1e-13 49.1 10.6 0.013 15.8 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CEP09389.1 - 4.1e-12 45.9 8.9 2e-05 24.5 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP09389.1 - 7.1e-07 28.7 8.7 0.73 9.5 0.5 5.7 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CEP09389.1 - 0.0099 15.8 9.4 2.1 8.4 0.2 5.3 5 2 0 5 5 5 1 Kelch motif Abhydrolase_1 PF00561.20 CEP09391.1 - 8.3e-54 182.9 0.0 1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP09391.1 - 0.0028 18.3 0.1 0.0046 17.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family 2-Hacid_dh_C PF02826.19 CEP09392.1 - 2.8e-47 160.4 0.0 4.8e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEP09392.1 - 3.3e-34 117.4 0.1 4.4e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CEP09392.1 - 7.6e-07 29.4 1.3 4e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 CEP09392.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 ACT domain DpaA_N PF16924.5 CEP09392.1 - 0.12 12.5 0.0 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain ABC2_membrane_2 PF12679.7 CEP09393.1 - 7.5e-05 22.1 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Yip1 PF04893.17 CEP09393.1 - 0.019 14.7 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Yip1 domain TMEM51 PF15345.6 CEP09393.1 - 0.02 14.7 14.8 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Borrelia_P83 PF05262.11 CEP09393.1 - 0.13 10.7 9.5 0.16 10.4 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Utp14 PF04615.13 CEP09393.1 - 0.32 9.5 20.3 0.42 9.1 20.3 1.1 1 0 0 1 1 1 0 Utp14 protein HemX PF04375.14 CEP09393.1 - 0.35 10.1 17.6 1.2 8.3 17.8 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Mitofilin PF09731.9 CEP09393.1 - 0.48 9.2 16.4 0.75 8.6 16.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein COX14 PF14880.6 CEP09393.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.7 3 0 0 3 3 2 0 Cytochrome oxidase c assembly EphA2_TM PF14575.6 CEP09393.1 - 1 10.3 14.5 1.8 9.5 0.0 3.3 3 2 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Plasmodium_Vir PF05795.11 CEP09393.1 - 2.5 7.4 19.7 65 2.8 19.7 2.2 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Connexin PF00029.19 CEP09393.1 - 4.4 7.0 6.8 0.44 10.3 1.9 1.8 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 CEP09393.1 - 5.1 6.8 14.0 0.39 10.4 3.0 2.9 1 1 1 3 3 3 0 FAM176 family DUF4834 PF16118.5 CEP09393.1 - 7.5 7.6 24.5 0.53 11.3 6.7 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Exo_endo_phos PF03372.23 CEP09394.1 - 3.2e-18 66.1 0.0 4.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.24 CEP09395.1 - 2.5e-117 392.5 20.3 2.9e-117 392.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP09395.1 - 1.7e-19 70.0 56.5 6.7e-17 61.4 28.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fer4_24 PF18109.1 CEP09396.1 - 0.019 15.2 1.5 1.6 9.1 0.0 3.2 3 1 1 4 4 4 0 Ferredoxin I 4Fe-4S cluster domain RepA_N PF06970.11 CEP09397.1 - 0.017 15.0 0.1 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Glycos_transf_2 PF00535.26 CEP09398.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 PMP22_Claudin PF00822.20 CEP09398.1 - 0.058 13.3 0.4 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pik1 PF11522.8 CEP09398.1 - 0.067 13.2 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 CRAL_TRIO PF00650.20 CEP09399.1 - 1.3e-27 96.5 0.3 5.1e-27 94.5 0.3 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP09399.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEP09399.1 - 0.052 13.7 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3020 PF11223.8 CEP09400.1 - 2.2e-16 60.1 4.7 2.2e-16 60.1 4.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Vezatin PF12632.7 CEP09401.1 - 5e-50 170.5 10.2 5e-50 170.5 10.2 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Asp4 PF16996.5 CEP09401.1 - 0.33 10.8 1.3 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 OmdA PF13376.6 CEP09401.1 - 6.7 6.8 7.7 31 4.7 0.0 3.2 2 1 1 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Methyltrn_RNA_3 PF02598.17 CEP09402.1 - 1.2e-94 317.0 0.0 1.4e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Gpr1_Fun34_YaaH PF01184.19 CEP09404.1 - 6.1e-73 244.8 18.3 7.1e-73 244.6 18.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TPR_11 PF13414.6 CEP09405.1 - 7.6e-13 47.9 7.0 0.0094 15.6 0.1 5.3 5 0 0 5 5 5 3 TPR repeat TPR_16 PF13432.6 CEP09405.1 - 2.8e-08 34.3 2.2 0.047 14.3 0.2 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 CEP09405.1 - 1.8e-06 27.8 7.4 2.9e-05 23.9 1.1 3.0 3 0 0 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.6 CEP09405.1 - 1.6e-05 25.3 5.2 0.14 12.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP09405.1 - 2.3e-05 24.9 0.4 0.81 10.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP09405.1 - 2.8e-05 23.7 8.8 0.51 10.3 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP09405.1 - 5.9e-05 23.2 4.9 6 7.5 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09405.1 - 0.00024 21.1 4.7 2.1 8.8 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Ribonuc_L-PSP PF01042.21 CEP09405.1 - 0.0014 18.6 0.1 0.37 10.8 0.1 2.7 2 0 0 2 2 2 1 Endoribonuclease L-PSP TPR_2 PF07719.17 CEP09405.1 - 0.0071 16.4 13.8 1.1 9.5 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Phage_ASH PF10554.9 CEP09405.1 - 0.072 13.4 0.5 0.17 12.3 0.5 1.6 1 0 0 1 1 1 0 Ash protein family ANAPC3 PF12895.7 CEP09405.1 - 1 9.6 5.3 7.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CEP09405.1 - 6 7.1 5.3 4.5 7.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Kelch_5 PF13854.6 CEP09407.1 - 8.6e-09 35.2 4.7 0.31 11.1 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CEP09407.1 - 1.8e-08 34.2 12.1 0.074 13.1 1.1 5.4 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEP09407.1 - 6.1e-08 32.8 7.8 9.8e-05 22.5 1.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP09407.1 - 4.2e-07 30.0 4.8 1.2 9.5 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CEP09407.1 - 5.2e-07 29.4 2.3 0.28 11.2 0.0 5.0 5 0 0 5 5 5 3 Kelch motif SKG6 PF08693.10 CEP09407.1 - 0.0006 19.2 3.0 0.0013 18.1 3.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.25 CEP09407.1 - 0.02 14.5 0.0 0.02 14.5 0.0 4.4 5 1 0 5 5 5 0 Kelch motif VSP PF03302.13 CEP09407.1 - 0.027 13.4 1.0 0.053 12.4 1.0 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Peptidase_M36 PF02128.15 CEP09408.1 - 5.4e-150 499.7 5.6 7.8e-150 499.1 5.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 CEP09408.1 - 1.6e-17 63.1 2.0 4.9e-17 61.5 2.0 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 CEP09408.1 - 0.0014 18.5 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain TsaE PF02367.17 CEP09408.1 - 0.11 12.5 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FYRN PF05964.14 CEP09409.1 - 1.5e-18 66.4 0.1 2.9e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CEP09409.1 - 9.1e-17 61.0 0.0 2.7e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus O-FucT PF10250.9 CEP09410.1 - 7.8e-20 71.8 1.0 2.7e-11 43.8 0.2 3.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase LON_substr_bdg PF02190.16 CEP09411.1 - 8.6e-21 74.8 0.1 7e-18 65.3 0.1 2.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 CEP09411.1 - 3.5e-11 42.7 13.8 7e-11 41.8 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP09411.1 - 1.1e-08 35.3 14.9 1.1e-08 35.3 14.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEP09411.1 - 2.1e-08 33.9 13.9 3.7e-08 33.1 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP09411.1 - 3.4e-08 33.2 13.9 6.5e-08 32.3 13.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP09411.1 - 4.1e-08 33.1 12.7 1.2e-07 31.6 12.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP09411.1 - 4.2e-07 29.7 13.1 1.4e-06 28.1 13.1 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CEP09411.1 - 1.1e-06 28.5 13.9 2.1e-06 27.6 13.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEP09411.1 - 3.7e-05 23.8 10.9 8.7e-05 22.6 10.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CEP09411.1 - 0.033 14.5 12.0 0.19 12.1 12.0 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain TerY_C PF15616.6 CEP09411.1 - 0.13 12.4 5.1 0.28 11.3 5.1 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 CEP09411.1 - 0.14 11.9 10.7 0.3 10.9 10.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CEP09411.1 - 0.39 10.9 9.4 0.75 10.0 9.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 CEP09411.1 - 0.39 10.6 9.5 1.3 9.0 9.5 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CEP09411.1 - 0.56 10.0 6.8 1.5 8.6 6.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger TFIIA PF03153.13 CEP09411.1 - 4 7.3 37.7 7.8 6.4 37.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CEP09412.1 - 5.6e-17 61.3 11.9 3.9e-09 36.5 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP09412.1 - 1.4e-12 47.3 20.6 3.6e-05 24.0 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP09412.1 - 1.7e-11 43.9 17.5 0.00013 22.5 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP09412.1 - 1.4e-07 31.4 15.1 2.5e-05 24.1 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP09412.1 - 0.00033 20.9 10.1 0.51 10.7 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CEP09412.1 - 0.0014 18.7 5.2 0.024 14.7 2.3 2.8 2 1 0 2 2 2 1 Zinc ribbon domain zf-LYAR PF08790.11 CEP09412.1 - 0.0025 17.7 8.1 0.1 12.5 0.3 3.2 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger Rad50_zn_hook PF04423.14 CEP09412.1 - 0.038 13.8 1.4 0.076 12.9 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif C1_4 PF07975.12 CEP09412.1 - 0.052 13.8 9.8 1.2 9.5 8.9 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 CEP09412.1 - 0.063 13.1 10.8 0.7 9.7 0.2 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 CEP09412.1 - 0.065 13.2 0.3 0.065 13.2 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 CEP09412.1 - 0.15 12.4 0.1 0.15 12.4 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEP09412.1 - 0.16 12.3 12.8 3.2 8.2 0.2 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 CEP09412.1 - 0.33 11.1 3.9 5.4 7.2 0.2 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain FYDLN_acid PF09538.10 CEP09412.1 - 0.33 11.6 3.2 16 6.2 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zinc-ribbons_6 PF07191.12 CEP09412.1 - 0.34 10.9 7.3 82 3.3 7.4 3.1 1 1 1 2 2 2 0 zinc-ribbons DUF2256 PF10013.9 CEP09412.1 - 0.45 10.7 3.3 4.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_UBZ PF18439.1 CEP09412.1 - 0.5 10.0 7.6 6 6.6 0.4 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CEP09412.1 - 0.6 10.2 10.1 25 5.0 10.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.18 CEP09412.1 - 0.8 9.6 5.7 14 5.6 0.2 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 CEP09412.1 - 1.6 8.7 7.8 1.8 8.6 2.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain XPA_N PF01286.18 CEP09412.1 - 3 8.0 7.1 10 6.3 0.1 3.2 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_3rep PF18868.1 CEP09412.1 - 3.7 8.3 11.0 19 5.9 7.5 3.2 2 1 0 2 2 1 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 CEP09412.1 - 8.3 6.7 14.9 22 5.3 2.4 3.6 1 1 2 3 3 3 0 AN1-like Zinc finger PX PF00787.24 CEP09413.1 - 1.2e-21 76.8 0.4 2.5e-21 75.8 0.4 1.5 1 0 0 1 1 1 1 PX domain ATP-synt_ab PF00006.25 CEP09414.1 - 1e-71 241.0 0.0 1.5e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CEP09414.1 - 3.7e-48 163.0 0.1 6.1e-48 162.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CEP09414.1 - 4.4e-20 72.0 0.6 1.2e-19 70.6 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PDZ_5 PF17817.1 CEP09416.1 - 0.00022 21.5 0.0 0.00091 19.5 0.0 2.1 1 0 0 1 1 1 1 PDZ domain tRNA_bind PF01588.20 CEP09417.1 - 6.7e-26 90.2 0.0 1.5e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain PBP PF01161.20 CEP09417.1 - 2.4e-14 53.8 0.1 5e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pex14_N PF04695.13 CEP09418.1 - 2e-30 106.6 0.4 2e-30 106.6 0.4 3.0 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TBCA PF02970.16 CEP09418.1 - 0.0025 18.1 0.9 0.0046 17.3 0.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF922 PF06037.11 CEP09418.1 - 0.39 10.5 1.9 0.94 9.3 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) Ras PF00071.22 CEP09419.1 - 3.8e-52 176.1 0.2 4.5e-52 175.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP09419.1 - 1.7e-33 115.4 0.1 2.8e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP09419.1 - 1.7e-15 56.9 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP09419.1 - 1.9e-07 30.7 0.1 2.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP09419.1 - 9.3e-07 28.9 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP09419.1 - 2.4e-06 27.3 0.4 1.9e-05 24.3 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP09419.1 - 5.2e-05 23.2 0.0 0.093 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CEP09419.1 - 0.0051 16.3 0.0 0.0086 15.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CEP09419.1 - 0.022 15.1 0.1 0.33 11.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CEP09419.1 - 0.033 13.4 0.8 2.1 7.4 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AIG1 PF04548.16 CEP09419.1 - 0.041 13.2 0.1 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 CEP09419.1 - 0.075 13.4 0.0 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 CEP09419.1 - 0.11 12.1 0.2 15 5.2 0.1 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CEP09419.1 - 0.13 11.8 0.1 5 6.6 0.1 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B MFS_1 PF07690.16 CEP09420.1 - 1.1e-39 136.3 14.4 4.6e-20 71.8 0.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CEP09420.1 - 1.1e-09 37.7 4.7 8.6e-09 34.7 0.6 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 CEP09420.1 - 2e-05 23.4 1.3 2e-05 23.4 1.3 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.20 CEP09420.1 - 0.0059 14.9 3.5 0.12 10.7 0.5 2.9 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family YMF19 PF02326.15 CEP09420.1 - 0.055 14.3 0.7 0.28 12.0 0.9 2.0 2 0 0 2 2 2 0 Plant ATP synthase F0 MFS_4 PF06779.14 CEP09420.1 - 0.089 12.1 7.4 1.4 8.2 7.4 2.4 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF21 PF01595.20 CEP09420.1 - 0.091 12.5 1.5 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Sugar_tr PF00083.24 CEP09420.1 - 0.18 10.6 18.7 0.5 9.2 10.9 3.4 1 1 1 2 2 2 0 Sugar (and other) transporter DUF3040 PF11239.8 CEP09420.1 - 0.36 11.1 3.9 11 6.4 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3040) FPN1 PF06963.12 CEP09420.1 - 1.1 7.7 6.9 0.049 12.2 0.7 1.9 2 0 0 2 2 2 0 Ferroportin1 (FPN1) 7tm_1 PF00001.21 CEP09420.1 - 1.3 8.3 8.3 6.2 6.1 2.2 2.5 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Mito_carr PF00153.27 CEP09421.1 - 1.3e-59 198.1 1.0 6.5e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.23 CEP09423.1 - 6.4e-13 48.3 0.1 1.5e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CEP09423.1 - 3.9e-09 36.2 0.0 3.9e-09 36.2 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 CEP09423.1 - 5.1e-06 26.2 0.1 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CEP09423.1 - 0.00034 20.7 0.1 0.00034 20.7 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEP09423.1 - 0.0006 20.3 0.0 0.0006 20.3 0.0 3.0 3 1 0 3 3 3 1 DUF2407 ubiquitin-like domain CUE PF02845.16 CEP09423.1 - 0.029 14.1 0.0 0.098 12.4 0.0 1.9 1 0 0 1 1 1 0 CUE domain Ubiquitin_4 PF18036.1 CEP09423.1 - 0.059 13.4 0.1 0.37 10.9 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain TraU PF06834.11 CEP09423.1 - 4.2 6.6 7.6 1.4 8.1 1.3 2.1 1 1 1 2 2 2 0 TraU protein DUF908 PF06012.12 CEP09423.1 - 9.2 5.6 11.9 0.24 10.8 5.6 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF543 PF04418.12 CEP09425.1 - 1.1e-24 86.2 0.0 1.2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.6 CEP09425.1 - 0.017 15.4 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 2TM domain DUF3021 PF11457.8 CEP09425.1 - 0.083 13.2 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PGF-CTERM PF18204.1 CEP09425.1 - 1.3 9.1 3.8 6.1 7.0 0.1 2.3 2 0 0 2 2 2 0 PGF-CTERM motif Sugar_tr PF00083.24 CEP09426.1 - 4.5e-93 312.6 36.3 8.2e-92 308.4 36.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP09426.1 - 1.4e-27 96.6 41.8 1.4e-18 67.0 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CEP09427.1 - 5.5e-75 252.1 0.0 7.6e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09427.1 - 1.4e-37 129.4 0.0 1.8e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP09427.1 - 5.5e-08 32.5 0.0 8.9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2252 PF10009.9 CEP09427.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Haspin_kinase PF12330.8 CEP09427.1 - 0.082 11.8 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Helicase_C PF00271.31 CEP09428.1 - 8e-07 29.4 0.0 9.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRKCSH PF07915.13 CEP09428.1 - 0.11 13.5 0.1 0.18 12.9 0.1 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Cpn60_TCP1 PF00118.24 CEP09429.1 - 1e-147 492.7 12.0 1.2e-147 492.5 12.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3271 PF11675.8 CEP09429.1 - 0.016 14.5 0.4 0.03 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) CRM1_repeat PF18777.1 CEP09429.1 - 0.083 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 CEP09429.1 - 0.086 13.0 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5442) SNF5 PF04855.12 CEP09430.1 - 2.8e-67 227.0 2.5 2.8e-67 227.0 2.5 2.2 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Cyclin_N PF00134.23 CEP09432.1 - 1.3e-37 128.3 0.1 6.9e-36 122.8 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEP09432.1 - 1.9e-26 92.5 0.2 4.7e-26 91.2 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF5413 PF17434.2 CEP09432.1 - 0.077 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Got1 PF04178.12 CEP09433.1 - 5.3e-28 97.7 8.1 7.5e-28 97.2 8.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Bromodomain PF00439.25 CEP09434.1 - 2.8e-17 62.5 0.2 9.6e-17 60.8 0.2 2.0 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 CEP09434.1 - 1.4e-06 27.9 0.2 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain EI24 PF07264.11 CEP09435.1 - 8.1e-11 42.5 1.3 1.1e-10 42.1 1.3 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) IQ PF00612.27 CEP09435.1 - 0.28 11.1 1.5 0.44 10.5 0.2 2.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif FMO-like PF00743.19 CEP09436.1 - 3e-13 49.0 0.1 1.2e-12 47.1 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CEP09436.1 - 3.5e-10 39.9 0.0 1.3e-08 34.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEP09436.1 - 1.5e-09 37.5 0.4 3.7e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEP09436.1 - 2.1e-06 27.2 0.0 0.0009 18.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP09436.1 - 9.5e-06 25.1 0.1 0.00039 19.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP09436.1 - 0.0026 17.0 0.3 0.024 13.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CEP09436.1 - 0.0072 15.9 0.0 0.29 10.7 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CEP09436.1 - 0.038 14.5 0.0 12 6.6 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CEP09436.1 - 0.048 12.9 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CEP09436.1 - 0.058 13.4 0.4 8.1 6.4 0.0 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 CEP09436.1 - 0.091 11.8 0.2 0.26 10.3 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CEP09436.1 - 0.11 11.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CEP09436.1 - 0.13 10.9 0.9 0.36 9.5 0.4 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 CEP09436.1 - 0.15 11.1 0.3 0.27 10.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain HATPase_c PF02518.26 CEP09437.1 - 5.4e-28 97.8 0.0 1.3e-26 93.3 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP09437.1 - 1.7e-23 82.9 2.2 9e-15 54.8 0.8 2.6 1 1 1 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 CEP09437.1 - 7.7e-16 57.9 1.7 3.4e-15 55.8 1.7 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TFIIA PF03153.13 CEP09437.1 - 0.0018 18.4 11.0 0.0018 18.4 11.0 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEP09437.1 - 0.014 15.1 15.5 0.033 13.8 15.5 1.7 1 0 0 1 1 1 0 Spt20 family Pet20 PF08692.10 CEP09437.1 - 3.2 8.5 8.7 0.1 13.3 1.4 2.3 3 0 0 3 3 3 0 Mitochondrial protein Pet20 SNF2_N PF00176.23 CEP09438.1 - 3.3e-59 200.4 1.8 8e-59 199.1 1.7 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP09438.1 - 7.8e-20 71.3 0.0 8e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP09438.1 - 6.2e-06 26.3 6.3 3.3e-05 23.9 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP09438.1 - 0.00016 21.0 0.1 0.00016 21.0 0.1 2.6 4 0 0 4 4 4 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 CEP09438.1 - 0.00029 21.0 0.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif WD40 PF00400.32 CEP09439.1 - 2.1e-19 69.5 3.0 4.4e-05 24.2 0.1 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09439.1 - 0.00019 21.6 0.0 5.3 7.4 0.0 4.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP09439.1 - 0.00093 18.2 0.2 1.5 7.7 0.1 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CHIP_TPR_N PF18391.1 CEP09439.1 - 0.0039 17.9 2.1 0.018 15.8 2.1 2.1 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain PQQ_3 PF13570.6 CEP09439.1 - 0.064 13.8 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 PQQ-like domain Astro_capsid_p PF12226.8 CEP09439.1 - 0.46 9.6 9.5 0.83 8.7 9.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.6 CEP09439.1 - 4.2 7.8 11.4 0.28 11.6 5.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexokinase_2 PF03727.16 CEP09440.1 - 1.5e-65 221.0 0.0 1.9e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP09440.1 - 4.9e-58 196.3 0.0 6.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Cu-oxidase_2 PF07731.14 CEP09441.1 - 1.4e-43 147.9 7.0 6.5e-41 139.3 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEP09441.1 - 6.1e-40 135.9 12.9 3.1e-39 133.7 1.8 4.1 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 CEP09441.1 - 2.6e-32 112.2 2.5 4.8e-29 101.5 0.3 3.9 4 0 0 4 4 4 2 Multicopper oxidase FTR1 PF03239.14 CEP09442.1 - 1.2e-71 241.4 14.2 1.5e-71 241.1 14.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family BacA PF02673.18 CEP09442.1 - 0.0067 16.2 1.5 0.0067 16.2 1.5 2.3 2 1 1 3 3 3 1 Bacitracin resistance protein BacA MgtE PF01769.16 CEP09442.1 - 1.5 9.2 15.7 2.7 8.4 0.9 3.0 3 0 0 3 3 3 0 Divalent cation transporter DUF2070 PF09843.9 CEP09442.1 - 2.5 6.3 8.9 1.3 7.3 1.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) LRR_4 PF12799.7 CEP09443.1 - 0.12 12.8 20.9 0.21 12.1 1.2 6.7 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) zf-CCHC PF00098.23 CEP09444.1 - 1.3e-06 28.2 19.3 3.8e-05 23.6 5.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP09444.1 - 0.85 9.4 21.5 2.8 7.7 6.5 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger IMUP PF15761.5 CEP09444.1 - 0.88 10.3 14.7 3.2 8.5 7.0 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein RVT_1 PF00078.27 CEP09445.1 - 2.1e-30 105.9 0.0 4.4e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP09445.1 - 4.6e-06 26.5 0.5 1.3e-05 25.0 0.5 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CEP09445.1 - 1.2e-05 26.0 1.2 3.8e-05 24.3 1.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP09445.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family NDC10_II PF16787.5 CEP09447.1 - 7.2e-06 25.3 0.0 8.1e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 E1-E2_ATPase PF00122.20 CEP09449.1 - 8.9e-50 168.7 4.2 8.9e-50 168.7 4.2 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP09449.1 - 1.1e-38 132.7 0.7 1.1e-38 132.7 0.7 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP09449.1 - 2.6e-21 75.5 0.2 7.5e-21 74.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP09449.1 - 1.2e-15 58.4 0.4 8.7e-13 49.0 0.0 3.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP09449.1 - 1.6e-14 53.3 0.0 4.4e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP09449.1 - 0.0028 17.4 0.5 0.0028 17.4 0.5 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SF1-HH PF16275.5 CEP09450.1 - 1.5e-38 131.6 4.3 4e-38 130.2 4.3 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 CEP09450.1 - 1.4e-09 37.6 11.0 1.6e-05 24.8 1.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 CEP09450.1 - 4.2e-08 32.9 0.3 8e-08 32.0 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 CEP09450.1 - 0.013 15.4 9.8 0.053 13.5 1.2 2.8 2 1 1 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 CEP09450.1 - 0.037 14.4 5.5 0.078 13.4 5.5 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.6 CEP09450.1 - 0.073 12.9 9.8 0.17 11.8 0.3 3.0 1 1 1 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 CEP09450.1 - 0.088 12.9 5.0 0.18 11.9 5.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-CCHC_2 PF13696.6 CEP09450.1 - 0.37 10.6 9.8 0.53 10.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP09450.1 - 0.44 10.3 8.5 3 7.6 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Anti-TRAP PF15777.5 CEP09450.1 - 0.61 10.1 2.7 1.5 8.8 2.7 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein CCDC-167 PF15188.6 CEP09450.1 - 2.2 8.7 5.3 4.9 7.6 0.5 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 BTB_2 PF02214.22 CEP09451.1 - 6.2e-11 42.5 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Flu_PB1 PF00602.17 CEP09451.1 - 0.053 11.6 0.0 0.067 11.3 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 BTB_3 PF16017.5 CEP09451.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain BTB_2 PF02214.22 CEP09452.1 - 1.7e-15 57.2 0.3 3e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CEP09452.1 - 0.04 14.2 0.4 0.067 13.4 0.4 1.4 1 0 0 1 1 1 0 BTB/POZ domain DsrD PF08679.11 CEP09452.1 - 0.28 11.5 2.2 2.2 8.6 0.5 2.7 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) IPK PF03770.16 CEP09454.1 - 3.5e-51 173.9 0.0 6.2e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1661 PF07877.11 CEP09454.1 - 0.091 12.5 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Coatomer_WDAD PF04053.14 CEP09455.1 - 1.4e-169 564.9 0.0 4.5e-168 559.9 0.0 2.3 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 CEP09455.1 - 1.5e-42 142.7 4.0 7.7e-09 36.1 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09455.1 - 2.2e-12 47.1 0.1 0.16 12.3 0.0 7.7 3 2 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CEP09455.1 - 6.2e-05 23.0 0.0 6.9 6.8 0.0 4.9 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 CEP09455.1 - 0.034 14.0 0.0 6.8 6.5 0.0 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS CobT PF06213.12 CEP09455.1 - 0.075 12.4 5.5 0.045 13.1 3.8 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nup160 PF11715.8 CEP09455.1 - 0.1 11.2 1.4 12 4.4 0.1 3.6 2 1 1 4 4 4 0 Nucleoporin Nup120/160 COMPASS-Shg1 PF05205.12 CEP09456.1 - 4.7e-17 62.6 1.0 5.4e-17 62.4 1.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DEC-1_N PF04625.13 CEP09456.1 - 0.14 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Fungal_trans PF04082.18 CEP09457.1 - 2.8e-31 108.6 0.9 4.5e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Far-17a_AIG1 PF04750.14 CEP09458.1 - 0.0002 20.8 24.6 0.00027 20.3 24.6 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF1772 PF08592.11 CEP09458.1 - 7.4 6.9 9.6 0.39 11.0 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Helitron_like_N PF14214.6 CEP09459.1 - 7.6e-10 39.3 0.0 1e-09 38.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 CEP09460.1 - 4.4e-44 151.0 0.0 6.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus XPB_DRD PF18458.1 CEP09460.1 - 0.2 11.6 0.0 0.51 10.3 0.0 1.7 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Chromo PF00385.24 CEP09463.1 - 2.8e-17 62.4 0.2 4.2e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP09463.1 - 0.013 15.4 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DDE_3 PF13358.6 CEP09464.1 - 1.7e-14 53.8 0.3 1.9e-14 53.7 0.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_pol_A_exo1 PF01612.20 CEP09468.1 - 1.5e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.23 CEP09470.1 - 0.57 10.4 13.8 0.1 12.7 1.2 3.1 4 0 0 4 4 4 0 Zinc knuckle zf-BED PF02892.15 CEP09470.1 - 2.7 8.1 11.5 3.2 7.8 2.0 3.3 3 0 0 3 3 3 0 BED zinc finger PIF1 PF05970.14 CEP09471.1 - 1.4e-22 80.4 0.0 2e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP09471.1 - 0.0021 17.8 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP09471.1 - 0.0076 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CEP09471.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CEP09471.1 - 0.097 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 CEP09471.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 CEP09471.1 - 0.16 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 CEP09471.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CEP09472.1 - 3.5e-35 121.9 0.0 7.6e-17 61.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.14 CEP09472.1 - 0.0078 14.2 0.0 0.01 13.8 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 CEP09473.1 - 2.3e-06 27.0 0.0 2.5e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DDE_3 PF13358.6 CEP09474.1 - 5.3e-21 74.9 0.0 1.6e-18 66.9 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP09474.1 - 0.00055 20.5 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP09474.1 - 0.0011 19.0 0.0 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 CEP09474.1 - 0.019 15.1 0.5 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Retrotrans_gag PF03732.17 CEP09479.1 - 1.5e-05 25.2 0.5 5e-05 23.5 0.5 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 CEP09479.1 - 0.023 14.4 0.1 0.077 12.7 0.1 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TerB PF05099.13 CEP09479.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB Lsm_interact PF05391.11 CEP09480.1 - 0.36 10.4 2.1 0.42 10.2 0.1 2.2 2 0 0 2 2 2 0 Lsm interaction motif MMS1_N PF10433.9 CEP09481.1 - 3.2e-59 200.9 1.6 5.5e-59 200.1 1.1 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEP09481.1 - 3.2e-41 141.7 0.1 4.9e-40 137.8 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region MAP65_ASE1 PF03999.12 CEP09481.1 - 1.8e-18 66.6 27.5 3.3e-18 65.7 27.5 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) TFIIA PF03153.13 CEP09481.1 - 0.02 14.9 22.2 0.033 14.2 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40_like PF17005.5 CEP09481.1 - 0.084 12.2 4.0 16 4.7 0.1 4.1 4 0 0 4 4 4 0 WD40-like domain DUF913 PF06025.12 CEP09481.1 - 0.14 11.1 6.2 0.3 10.0 6.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spt20 PF12090.8 CEP09481.1 - 0.18 11.4 24.9 0.37 10.4 24.9 1.5 1 0 0 1 1 1 0 Spt20 family DUF572 PF04502.13 CEP09481.1 - 0.25 10.9 10.7 0.43 10.1 10.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 CEP09481.1 - 0.27 11.0 10.3 0.46 10.3 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CEP09481.1 - 0.57 9.1 22.6 0.87 8.5 22.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MMR1 PF08505.10 CEP09481.1 - 2.9 8.1 17.9 5.7 7.2 17.9 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Roughex PF06020.11 CEP09481.1 - 6.3 5.8 13.0 10 5.1 13.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CobT PF06213.12 CEP09481.1 - 6.4 6.1 14.0 12 5.2 14.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDE_3 PF13358.6 CEP09482.1 - 6.2e-12 45.5 0.0 9.7e-06 25.4 0.0 2.3 1 1 0 2 2 2 2 DDE superfamily endonuclease Syd PF07348.12 CEP09482.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Syd protein (SUKH-2) Kinesin PF00225.23 CEP09485.1 - 9.1e-106 353.5 1.2 9.1e-106 353.5 1.2 2.8 3 2 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP09485.1 - 3.8e-23 82.1 0.0 3.8e-23 82.1 0.0 3.1 3 1 0 3 3 3 1 Microtubule binding MFS_1 PF07690.16 CEP09487.1 - 6.4e-37 127.3 16.4 6.4e-37 127.3 16.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP09487.1 - 1.8e-08 33.7 20.2 9.6e-08 31.3 1.0 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 CEP09487.1 - 0.0023 16.3 2.8 0.006 14.9 2.8 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family RasGEF PF00617.19 CEP09488.1 - 1.5e-57 194.7 0.6 1.5e-57 194.7 0.6 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEP09488.1 - 8.4e-29 99.9 1.0 3e-28 98.1 0.2 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 CEP09488.1 - 5.4e-14 51.5 0.0 1.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP09488.1 - 4.5e-10 39.1 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP09488.1 - 1.5e-09 37.6 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAT PF02259.23 CEP09488.1 - 0.00077 18.8 0.4 0.0021 17.4 0.4 1.6 1 0 0 1 1 1 1 FAT domain ATG16 PF08614.11 CEP09489.1 - 0.045 14.0 5.3 0.053 13.7 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AATF-Che1 PF13339.6 CEP09490.1 - 6.8e-32 111.0 2.3 6.8e-32 111.0 2.3 3.7 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CEP09490.1 - 2.1e-27 95.4 0.3 2.1e-27 95.4 0.3 2.8 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Apolipo_F PF15148.6 CEP09490.1 - 0.025 14.1 0.4 0.045 13.2 0.4 1.3 1 0 0 1 1 1 0 Apolipoprotein F zf-RRN7 PF11781.8 CEP09491.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RPA_interact_C PF14768.6 CEP09491.1 - 0.14 12.8 0.0 0.5 11.0 0.0 2.0 2 0 0 2 2 2 0 Replication protein A interacting C-terminal PBP1_TM PF14812.6 CEP09491.1 - 0.45 10.9 4.9 0.41 11.1 0.8 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LON_substr_bdg PF02190.16 CEP09492.1 - 4.4e-18 65.9 0.0 6.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 CEP09492.1 - 5.6e-08 32.8 24.5 4e-05 23.7 8.8 2.4 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CEP09492.1 - 3.4e-07 30.2 20.6 0.0012 18.8 4.7 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEP09492.1 - 9.2e-06 25.4 19.7 0.0043 16.9 8.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP09492.1 - 4.8e-05 23.1 20.0 0.00064 19.5 7.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP09492.1 - 6e-05 22.9 22.7 0.00042 20.2 9.3 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 CEP09492.1 - 0.00012 21.9 20.6 0.0027 17.5 10.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP09492.1 - 0.0034 17.2 24.9 0.027 14.3 8.8 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CEP09492.1 - 0.0086 16.2 18.0 0.11 12.6 4.4 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CEP09492.1 - 0.11 12.4 13.3 0.071 13.0 1.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf_C2H2_13 PF18508.1 CEP09492.1 - 0.87 9.2 4.8 6.5 6.4 0.5 3.5 3 0 0 3 3 3 0 Zinc finger domain NMD3 PF04981.13 CEP09492.1 - 1.2 8.5 4.5 0.98 8.8 0.5 2.1 2 0 0 2 2 2 0 NMD3 family zf-RING_2 PF13639.6 CEP09492.1 - 1.3 9.4 24.1 0.45 10.9 9.6 2.7 2 0 0 2 2 2 0 Ring finger domain XPG_I_2 PF12813.7 CEP09493.1 - 7.8e-17 61.6 0.8 4.8e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 XPG domain containing XPG_N PF00752.17 CEP09493.1 - 3.6e-07 30.6 0.0 1.4e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEP09493.1 - 0.013 15.8 0.0 0.059 13.7 0.0 2.2 1 0 0 1 1 1 0 XPG I-region DnaJ PF00226.31 CEP09494.1 - 4.8e-13 49.0 1.4 8.7e-13 48.2 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain T3SS_needle_F PF09392.10 CEP09494.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Oxysterol_BP PF01237.18 CEP09495.1 - 8e-117 390.2 6.6 8e-117 390.2 6.6 2.2 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 CEP09495.1 - 1.4e-20 73.4 0.2 3.7e-20 72.0 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP09495.1 - 4.2e-10 40.1 2.5 8.6e-10 39.1 0.2 2.8 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CEP09495.1 - 0.012 16.0 11.0 0.32 11.5 1.3 3.7 3 1 1 4 4 4 0 Pleckstrin homology domain GOLD_2 PF13897.6 CEP09495.1 - 0.097 13.2 0.6 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking EF-hand_1 PF00036.32 CEP09496.1 - 3.8e-24 82.4 7.9 2.2e-06 26.8 0.1 5.8 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 CEP09496.1 - 7.7e-24 83.9 1.7 2.2e-10 40.8 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEP09496.1 - 1.9e-23 80.3 5.1 0.00032 20.4 0.0 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.6 CEP09496.1 - 1.7e-20 71.5 5.1 0.00013 21.3 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEP09496.1 - 8.5e-18 63.9 5.7 4.3e-10 39.3 0.0 4.7 3 3 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.6 CEP09496.1 - 0.025 14.9 0.0 10 6.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP09496.1 - 0.28 11.5 2.5 2.6 8.4 0.9 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pex14_N PF04695.13 CEP09496.1 - 0.84 10.3 11.8 1.2 9.8 11.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.32 CEP09497.1 - 1.2e-22 77.7 2.0 1.1e-05 24.6 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CEP09497.1 - 3.5e-20 70.1 1.8 0.00025 20.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CEP09497.1 - 4e-18 65.6 2.6 4e-08 33.6 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEP09497.1 - 6.2e-15 54.8 4.0 2.9e-08 33.4 0.0 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEP09497.1 - 4.6e-11 41.7 8.8 0.0012 18.2 0.0 4.3 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 CEP09497.1 - 0.035 14.4 0.5 1.8 8.9 0.1 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP09497.1 - 0.088 12.8 0.3 0.29 11.1 0.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand NinF PF05810.12 CEP09497.1 - 0.17 11.8 0.6 0.31 10.9 0.6 1.4 1 0 0 1 1 1 0 NinF protein EF-hand_10 PF14788.6 CEP09497.1 - 0.3 11.0 2.9 11 5.9 0.0 3.2 3 1 1 4 4 4 0 EF hand Ank_2 PF12796.7 CEP09498.1 - 3.6e-40 136.4 13.3 9.7e-13 48.5 0.5 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEP09498.1 - 5e-32 109.5 11.1 1.8e-07 31.3 0.1 6.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP09498.1 - 4.6e-29 100.4 8.0 2.3e-06 28.1 0.0 6.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP09498.1 - 1.6e-26 89.4 10.2 0.022 15.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 CEP09498.1 - 1.3e-18 66.5 11.1 0.069 13.6 0.1 8.2 8 0 0 8 8 8 7 Ankyrin repeat Plant_tran PF04827.14 CEP09498.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein Ribosomal_L37ae PF01780.19 CEP09499.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CEP09499.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CEP09499.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 CEP09499.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 CEP09499.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 CEP09499.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 CEP09499.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 CEP09499.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CEP09499.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_L29 PF00831.23 CEP09500.1 - 2.5e-14 53.0 3.1 2.5e-14 53.0 3.1 2.1 1 1 1 2 2 2 1 Ribosomal L29 protein CCDC14 PF15254.6 CEP09500.1 - 0.0013 17.5 3.0 0.0017 17.1 3.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 Ribosomal_S9 PF00380.19 CEP09500.1 - 0.033 14.7 5.2 0.054 14.0 5.1 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF5308 PF17233.2 CEP09500.1 - 0.27 11.4 2.9 0.38 11.0 2.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) HMG_box PF00505.19 CEP09501.1 - 4.3e-14 52.7 1.1 8.9e-14 51.7 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP09501.1 - 5.4e-08 33.3 0.8 1.3e-07 32.1 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain Phage_prot_Gp6 PF05133.14 CEP09501.1 - 0.055 12.6 3.3 1.4 7.9 0.8 2.2 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like HSP90 PF00183.18 CEP09503.1 - 3.4e-233 775.2 26.9 4.3e-233 774.9 26.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CEP09503.1 - 3.9e-15 56.3 0.0 8.4e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP09503.1 - 2.1e-10 40.5 0.1 2.1e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 CEP09503.1 - 0.082 12.9 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN WD40 PF00400.32 CEP09507.1 - 9.5e-41 137.0 17.2 6.6e-07 29.9 0.1 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09507.1 - 3.2e-12 46.6 2.4 0.14 12.4 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP09507.1 - 1.8e-10 40.6 1.3 0.0004 19.8 0.0 3.0 1 1 1 3 3 3 3 WD40-like domain F-box-like PF12937.7 CEP09507.1 - 2.2e-10 40.2 0.8 4.7e-10 39.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CEP09507.1 - 1.5e-09 37.0 13.5 0.0061 15.3 0.1 6.3 2 1 3 7 7 7 3 Nucleoporin Nup120/160 F-box PF00646.33 CEP09507.1 - 1.7e-06 27.8 0.3 4.3e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 CEP09507.1 - 0.00021 20.3 3.2 0.48 9.3 0.0 3.9 2 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 CEP09507.1 - 0.00057 19.5 0.3 0.84 9.2 0.1 2.5 2 0 0 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 CEP09507.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box PQQ PF01011.21 CEP09507.1 - 0.0064 16.4 0.2 9.4 6.4 0.0 4.1 5 0 0 5 5 5 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 CEP09507.1 - 0.013 14.5 0.2 4.9 6.0 0.0 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SprA-related PF12118.8 CEP09507.1 - 4 6.5 9.2 6.2 5.9 9.2 1.2 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.9 CEP09507.1 - 7.9 4.9 7.3 11 4.4 7.3 1.1 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 CEP09507.1 - 9.8 5.1 13.7 14 4.6 12.5 1.7 2 0 0 2 2 2 0 Protein family FAM199X Radical_SAM PF04055.21 CEP09508.1 - 2.8e-14 53.8 0.0 1.1e-13 51.9 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Nup35_RRM PF05172.13 CEP09508.1 - 1.2e-09 38.0 2.0 1.9e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Fer4_14 PF13394.6 CEP09508.1 - 6.8e-05 23.0 0.7 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Nup35_RRM_2 PF14605.6 CEP09508.1 - 0.00026 20.9 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Fer4_12 PF13353.6 CEP09508.1 - 0.021 15.1 0.0 0.077 13.3 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain Nucleoporin_FG PF13634.6 CEP09508.1 - 0.71 10.8 59.7 0.042 14.7 24.3 3.5 2 1 1 3 3 3 0 Nucleoporin FG repeat region SprA-related PF12118.8 CEP09508.1 - 5.8 6.0 16.6 9.9 5.2 16.6 1.3 1 0 0 1 1 1 0 SprA-related family zf-C2H2 PF00096.26 CEP09509.1 - 4.2e-11 42.7 8.4 3.7e-07 30.3 1.3 6.0 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP09509.1 - 1.7e-06 28.1 2.6 1.7e-06 28.1 2.6 5.3 5 1 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP09509.1 - 7.7e-05 23.2 7.3 0.002 18.8 0.6 5.3 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEP09509.1 - 8.6e-05 22.7 2.6 0.021 14.9 0.4 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-met PF12874.7 CEP09509.1 - 0.015 15.6 8.2 0.16 12.4 1.7 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP09509.1 - 0.26 11.6 11.8 1.1 9.6 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CEP09509.1 - 1.7 8.5 12.1 6 6.7 2.3 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain HMG_box PF00505.19 CEP09510.1 - 9.3e-07 29.2 0.1 9.3e-07 29.2 0.1 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP09510.1 - 0.0001 22.8 0.4 0.00018 22.0 0.3 1.5 1 1 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 CEP09510.1 - 0.011 16.0 0.1 0.02 15.1 0.1 1.4 1 1 0 1 1 1 0 Protamine and protamine like Tir_receptor_C PF07489.11 CEP09510.1 - 0.089 12.8 1.2 0.11 12.4 1.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PH PF00169.29 CEP09512.1 - 1.5e-11 44.7 0.2 2.1e-10 41.0 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 CEP09512.1 - 6.7e-06 26.5 0.6 7.5e-05 23.1 0.0 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain ORC_WH_C PF18137.1 CEP09512.1 - 0.51 10.4 2.9 0.72 9.9 0.0 2.6 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal DUF1356 PF07092.12 CEP09513.1 - 0.21 10.8 1.3 0.46 9.7 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) NOA36 PF06524.12 CEP09513.1 - 1.3 8.3 8.3 2.1 7.6 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein Vps52 PF04129.12 CEP09514.1 - 2.2e-133 445.7 9.7 3.2e-133 445.2 9.7 1.2 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CEP09514.1 - 1.1e-06 27.4 15.7 5.1e-06 25.2 1.3 3.2 3 0 0 3 3 3 3 Exocyst complex component Sec3 COG2 PF06148.11 CEP09514.1 - 0.00044 20.4 2.8 0.0013 18.8 2.8 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF5069 PF16798.5 CEP09514.1 - 0.011 16.0 0.6 0.033 14.4 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) CHDCT2 PF08074.11 CEP09514.1 - 0.032 14.4 2.6 0.44 10.7 0.9 3.1 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain UPF0449 PF15136.6 CEP09514.1 - 0.18 12.3 1.8 0.63 10.5 1.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 GCIP PF13324.6 CEP09514.1 - 1 8.9 7.0 1.8 8.1 7.0 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Atg14 PF10186.9 CEP09515.1 - 0.0077 15.3 2.7 0.012 14.7 2.7 1.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1043 PF06295.12 CEP09515.1 - 0.073 13.1 3.2 0.13 12.3 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) zf-H2C2_2 PF13465.6 CEP09517.1 - 2.4e-11 43.5 15.5 2.2e-07 31.0 2.6 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP09517.1 - 2.9e-08 33.7 6.3 2.5e-06 27.6 0.4 4.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP09517.1 - 6e-06 26.7 30.0 0.0012 19.5 0.7 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP09517.1 - 0.00014 21.7 2.5 0.61 10.2 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP09517.1 - 0.0032 17.7 12.4 0.12 12.7 0.4 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding YL1 PF05764.13 CEP09518.1 - 0.03 14.4 3.2 0.037 14.2 3.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Exo_endo_phos_2 PF14529.6 CEP09518.1 - 0.053 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase PIF1 PF05970.14 CEP09519.1 - 1.4e-41 142.9 0.0 1.5e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CEP09521.1 - 8.1e-39 133.8 0.0 9.5e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SOCS_box PF07525.16 CEP09522.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 SOCS box NDC10_II PF16787.5 CEP09523.1 - 2.8e-17 62.8 0.2 3.4e-17 62.5 0.2 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 TMEM214 PF10151.9 CEP09526.1 - 0.013 14.0 0.2 0.016 13.7 0.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator BRF1 PF07741.13 CEP09526.1 - 0.087 13.2 2.4 0.13 12.6 2.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DDE_3 PF13358.6 CEP09528.1 - 3.8e-26 91.6 0.0 6.8e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP09528.1 - 1.8e-05 24.8 1.4 4.8e-05 23.4 1.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CEP09528.1 - 0.00053 20.5 0.5 0.0023 18.5 0.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP09528.1 - 0.00072 19.5 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP09528.1 - 0.0032 16.8 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 FeoC PF09012.10 CEP09528.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_23 PF13384.6 CEP09528.1 - 0.14 12.0 0.2 0.37 10.6 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Exo_endo_phos_2 PF14529.6 CEP09529.1 - 2.1e-09 37.2 1.6 3.9e-09 36.4 0.2 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase AAA_12 PF13087.6 CEP09529.1 - 0.049 13.3 3.4 0.061 12.9 1.0 2.0 1 1 1 2 2 2 0 AAA domain PMBR PF09373.10 CEP09529.1 - 0.11 12.7 0.5 18 5.7 0.1 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Exo_endo_phos PF03372.23 CEP09529.1 - 0.19 11.2 0.8 0.43 10.1 0.8 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Hrs_helical PF12210.8 CEP09529.1 - 0.29 11.7 1.2 26 5.4 0.1 3.1 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate KELK PF15796.5 CEP09529.1 - 1.7 9.2 3.6 12 6.4 1.1 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RVT_1 PF00078.27 CEP09530.1 - 6.4e-12 45.5 0.0 8.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lambda_Kil PF06301.11 CEP09530.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein Ku_PK_bind PF08785.11 CEP09532.1 - 0.072 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like GIT_SHD PF08518.11 CEP09536.1 - 0.068 12.8 0.6 0.18 11.5 0.6 1.7 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Phage_lambda_P PF06992.11 CEP09540.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein P LRR_2 PF07723.13 CEP09541.1 - 0.00043 20.8 3.6 0.61 10.9 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat F-box PF00646.33 CEP09541.1 - 0.033 14.1 1.9 0.054 13.4 0.1 2.4 3 0 0 3 3 3 0 F-box domain LRR_6 PF13516.6 CEP09541.1 - 0.18 12.0 8.2 27 5.1 0.1 5.1 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.7 CEP09541.1 - 0.27 11.2 5.7 0.082 12.8 1.1 2.6 3 0 0 3 3 3 0 F-box-like Pkinase PF00069.25 CEP09544.1 - 3.3e-65 220.1 0.0 5.7e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09544.1 - 1.8e-34 119.2 0.0 3.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CEP09544.1 - 1.6e-17 63.1 32.1 3.3e-11 42.9 9.8 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 CEP09544.1 - 1.1e-13 51.0 8.3 3.8e-08 33.3 0.9 2.8 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 CEP09544.1 - 1.3e-09 38.6 0.4 4.3e-09 36.9 0.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CEP09544.1 - 4.3e-05 23.7 0.2 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 C2 domain C1_2 PF03107.16 CEP09544.1 - 0.099 13.0 21.0 0.031 14.6 7.1 2.6 2 0 0 2 2 2 0 C1 domain Haspin_kinase PF12330.8 CEP09544.1 - 0.13 11.1 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SAGA-Tad1 PF12767.7 CEP09544.1 - 1.7 8.3 5.8 4.5 6.9 5.8 1.7 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.13 CEP09544.1 - 2.6 8.0 20.1 2.4 8.1 15.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDE_Tnp_1_7 PF13843.6 CEP09545.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Transposase IS4 RRM_1 PF00076.22 CEP09546.1 - 2.4e-39 133.0 0.0 7.1e-20 70.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP09546.1 - 1.1e-05 25.2 0.0 0.2 11.5 0.0 3.0 2 2 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CEP09546.1 - 5.3e-05 23.1 0.0 0.043 13.8 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif CDC45 PF02724.14 CEP09546.1 - 0.25 9.6 8.3 0.32 9.2 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 CEP09546.1 - 0.39 10.9 7.9 2.2 8.4 7.2 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SURF2 PF05477.11 CEP09546.1 - 1.1 8.9 7.8 1.7 8.3 7.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Presenilin PF01080.17 CEP09546.1 - 1.5 7.5 5.5 1.7 7.3 5.5 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 CEP09546.1 - 6.1 4.8 11.9 9.5 4.2 11.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sec62 PF03839.16 CEP09546.1 - 6.1 6.3 6.3 8.2 5.9 6.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 HSP70 PF00012.20 CEP09547.1 - 2.4e-06 26.1 0.4 0.00054 18.3 0.0 3.3 3 0 0 3 3 3 3 Hsp70 protein Rsm22 PF09243.10 CEP09548.1 - 1.4e-71 241.0 0.0 1.9e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 CEP09548.1 - 0.00024 21.7 0.0 0.0006 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP09548.1 - 0.0003 21.5 0.0 0.00069 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP09548.1 - 0.00037 20.3 0.0 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP09548.1 - 0.00048 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP09548.1 - 0.076 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CEP09548.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family HSP70 PF00012.20 CEP09549.1 - 5e-05 21.7 0.8 0.00016 20.0 0.1 2.1 3 0 0 3 3 3 1 Hsp70 protein ROK PF00480.20 CEP09549.1 - 0.21 11.0 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 ROK family DDE_3 PF13358.6 CEP09550.1 - 8.2e-17 61.3 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L6e_N PF03868.15 CEP09550.1 - 0.052 13.8 0.6 0.65 10.3 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain GGACT PF06094.12 CEP09550.1 - 0.094 13.3 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Spectrin PF00435.21 CEP09550.1 - 0.52 10.8 3.4 0.23 11.9 0.7 1.7 2 0 0 2 2 2 0 Spectrin repeat VHS PF00790.19 CEP09551.1 - 7.1e-16 58.3 0.2 3.5e-14 52.8 0.4 2.7 2 2 1 3 3 3 1 VHS domain GAT PF03127.14 CEP09551.1 - 5.1e-15 55.5 1.1 5.1e-15 55.5 1.1 2.3 2 0 0 2 2 2 1 GAT domain DUF4075 PF13294.6 CEP09551.1 - 0.068 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF3479 PF11965.8 CEP09551.1 - 0.087 12.9 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Nop PF01798.18 CEP09551.1 - 0.12 11.9 2.8 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin Det1 PF09737.9 CEP09551.1 - 0.14 11.2 5.3 0.19 10.7 5.3 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Presenilin PF01080.17 CEP09551.1 - 9.2 4.9 8.8 17 4.1 8.8 1.4 1 0 0 1 1 1 0 Presenilin DUF4007 PF13182.6 CEP09553.1 - 0.03 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) SLAM PF06214.11 CEP09553.1 - 0.072 13.1 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein DDE_3 PF13358.6 CEP09554.1 - 3.7e-20 72.2 0.1 6.1e-19 68.2 0.1 2.5 1 1 0 1 1 1 1 DDE superfamily endonuclease BLM10_mid PF16507.5 CEP09555.1 - 1e-170 568.9 0.0 9.3e-170 565.7 0.0 2.2 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CEP09555.1 - 4.4e-34 116.3 0.2 6.7e-32 109.3 0.0 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 CEP09555.1 - 0.00064 20.0 0.0 0.0051 17.1 0.0 2.5 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 CEP09555.1 - 0.0021 18.1 0.0 7.7 7.1 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.8 CEP09555.1 - 0.014 15.0 0.4 7.2 6.1 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal HEAT_2 PF13646.6 CEP09555.1 - 0.043 14.2 0.1 1.7 9.1 0.0 3.4 2 1 1 3 3 3 0 HEAT repeats Ras PF00071.22 CEP09556.1 - 6.2e-53 178.7 0.0 7e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP09556.1 - 5.1e-19 68.7 0.0 6.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP09556.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP09556.1 - 0.049 13.2 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Metallophos PF00149.28 CEP09557.1 - 1.7e-14 54.8 0.1 3.7e-14 53.7 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP09557.1 - 0.087 13.3 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Nudix_N_2 PF14803.6 CEP09557.1 - 0.19 11.7 1.9 0.25 11.3 0.1 2.2 3 0 0 3 3 3 0 Nudix N-terminal Mannosyl_trans PF05007.13 CEP09558.1 - 2.9e-79 266.6 24.6 3.4e-77 259.8 23.3 2.5 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) MPC PF03650.13 CEP09558.1 - 1.4e-33 115.4 0.0 2.8e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Myotub-related PF06602.14 CEP09559.1 - 1.3e-148 494.6 0.2 1.6e-148 494.4 0.2 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CEP09559.1 - 0.0052 16.4 0.3 0.014 15.0 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEP09559.1 - 0.02 14.7 0.1 0.047 13.5 0.1 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GRAM PF02893.20 CEP09559.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 GRAM domain CYSTM PF12734.7 CEP09560.1 - 0.00067 19.9 24.5 0.0036 17.6 24.5 2.0 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Sad1_UNC PF07738.13 CEP09561.1 - 3.3e-23 82.1 0.1 1.7e-22 79.8 0.0 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal CobU PF02283.16 CEP09561.1 - 0.17 11.4 0.1 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RRM_1 PF00076.22 CEP09563.1 - 5.1e-14 51.9 0.1 9.3e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CEP09563.1 - 1.5e-11 43.8 10.7 1e-06 28.5 3.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CEP09563.1 - 0.0017 18.1 5.1 0.44 10.4 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle RRM_occluded PF16842.5 CEP09563.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCHC_4 PF14392.6 CEP09563.1 - 0.1 12.3 5.5 2.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEP09563.1 - 0.13 12.1 0.6 0.13 12.1 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP09563.1 - 8.4 6.5 8.6 7.5 6.6 0.1 2.8 3 0 0 3 3 3 0 Zinc knuckle Glucosamine_iso PF01182.20 CEP09564.1 - 6.1e-76 255.2 0.0 7e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FNIP_M PF14637.6 CEP09566.1 - 3.9e-58 197.1 0.1 6.5e-58 196.4 0.1 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 CEP09566.1 - 6.3e-47 159.7 0.2 1.4e-46 158.5 0.2 1.6 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 CEP09566.1 - 9.7e-18 65.6 0.0 9.7e-18 65.6 0.0 4.4 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus Actin PF00022.19 CEP09567.1 - 1.3e-147 491.7 0.0 1.5e-147 491.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEP09567.1 - 9.8e-08 31.2 0.0 6.3e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 CEP09567.1 - 0.45 9.7 1.2 4.9 6.3 0.1 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Peptidase_M16 PF00675.20 CEP09568.1 - 7.2e-22 78.0 0.9 1.3e-21 77.2 0.9 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEP09568.1 - 5.1e-18 65.7 0.0 1.3e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain HHH_8 PF14716.6 CEP09568.1 - 0.051 14.0 0.8 4.9 7.6 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain CTP_transf_1 PF01148.20 CEP09570.1 - 2.6e-79 266.7 24.7 3.2e-79 266.4 24.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4389 PF14333.6 CEP09570.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4389) CDP-OH_P_transf PF01066.21 CEP09571.1 - 1.1e-17 64.5 0.0 1.1e-17 64.5 0.0 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Rpn3_C PF08375.11 CEP09572.1 - 3.2e-30 104.3 1.8 3.2e-30 104.3 1.8 3.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CEP09572.1 - 1.1e-21 77.2 1.2 6.1e-21 74.9 0.0 2.8 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.17 CEP09572.1 - 0.21 11.8 6.9 0.08 13.1 1.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 CEP09573.1 - 1.9e-06 28.0 4.7 5.2e-06 26.6 4.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP09573.1 - 0.00016 21.9 3.5 0.00016 21.9 3.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEP09573.1 - 0.0018 18.6 2.3 0.011 16.1 0.4 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) TIP120 PF08623.10 CEP09573.1 - 0.0035 17.1 0.8 0.0066 16.2 0.8 1.6 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF3450 PF11932.8 CEP09573.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-DBF PF07535.12 CEP09573.1 - 0.045 13.9 1.5 0.09 12.9 0.6 2.0 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2 PF00096.26 CEP09573.1 - 0.084 13.4 2.7 0.31 11.6 2.7 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3583 PF12126.8 CEP09574.1 - 0.0047 16.4 0.1 0.0097 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) hNIFK_binding PF12196.8 CEP09574.1 - 0.027 14.0 0.1 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK FTO_CTD PF12934.7 CEP09574.1 - 0.92 9.3 5.0 1.4 8.7 0.2 2.9 2 1 1 3 3 3 0 FTO C-terminal domain Cytochrom_B562 PF07361.11 CEP09575.1 - 0.019 15.6 7.5 0.93 10.2 0.1 2.7 2 1 0 2 2 2 0 Cytochrome b562 TRH PF05438.12 CEP09575.1 - 0.027 14.2 6.8 0.015 15.1 4.6 1.6 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) ADIP PF11559.8 CEP09575.1 - 0.33 11.0 12.7 0.97 9.5 12.7 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2868 PF11067.8 CEP09575.1 - 1.1 8.7 11.7 0.12 11.9 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) Fib_alpha PF08702.10 CEP09575.1 - 2.5 8.3 12.9 1.5 9.0 8.7 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-RVT PF13966.6 CEP09576.1 - 2.3e-06 28.2 0.3 5e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF726 PF05277.12 CEP09577.1 - 6.4e-120 400.2 0.2 1.1e-119 399.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 CEP09577.1 - 6.1 6.9 14.2 0.51 10.4 4.7 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III tRNA-synt_1c PF00749.21 CEP09578.1 - 6.5e-107 357.0 0.0 8.9e-107 356.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CEP09578.1 - 1.2e-42 145.7 0.2 4.1e-42 144.0 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CEP09578.1 - 6.3e-07 29.7 0.0 2.3e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C_2 PF13410.6 CEP09578.1 - 0.0022 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP09578.1 - 0.039 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP09578.1 - 0.11 12.7 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_N PF08240.12 CEP09579.1 - 4.7e-19 68.3 0.1 7.8e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP09579.1 - 2.9e-16 59.6 0.0 5.9e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEP09579.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CEP09579.1 - 0.065 14.3 0.0 0.09 13.8 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LYTB PF02401.18 CEP09579.1 - 0.17 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 LytB protein SRP54 PF00448.22 CEP09579.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mannosyl_trans3 PF11051.8 CEP09580.1 - 5.9e-43 147.2 0.1 9.9e-42 143.2 0.1 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 CEP09580.1 - 0.07 13.1 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_15 PF01793.16 CEP09581.1 - 6.6e-66 222.8 14.0 8.3e-66 222.5 14.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RMMBL PF07521.12 CEP09581.1 - 0.043 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Imm59 PF15597.6 CEP09581.1 - 0.11 12.9 0.3 0.11 12.9 0.3 2.6 2 2 0 2 2 2 0 Immunity protein 59 Na_Ca_ex PF01699.24 CEP09582.1 - 9.9e-42 142.4 45.3 1.1e-22 80.6 20.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein NMO PF03060.15 CEP09583.1 - 1.3e-61 208.9 0.1 1.4e-61 208.7 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CEP09583.1 - 1.9e-06 27.2 0.0 0.051 12.6 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CEP09583.1 - 0.00091 18.4 0.1 0.059 12.4 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 CEP09583.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 CEP09583.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase YtxH PF12732.7 CEP09585.1 - 0.17 12.4 28.2 0.25 11.9 3.5 5.3 4 2 0 4 4 4 0 YtxH-like protein TMP_2 PF06791.13 CEP09585.1 - 0.18 11.4 4.1 0.082 12.6 0.9 2.0 2 0 0 2 2 2 0 Prophage tail length tape measure protein ApoLp-III PF07464.11 CEP09585.1 - 2 8.5 13.6 0.1 12.7 1.0 3.6 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 CEP09585.1 - 9.3 6.1 18.8 1.1 9.1 5.4 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Qua1 PF16274.5 CEP09585.1 - 9.6 6.1 6.3 34 4.4 0.2 3.2 4 0 0 4 4 4 0 Qua1 domain tRNA-synt_2 PF00152.20 CEP09586.1 - 8.1e-104 347.1 0.1 1e-103 346.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEP09586.1 - 1.6e-06 28.0 0.0 6.9e-06 26.0 0.0 2.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEP09586.1 - 1.2e-05 25.0 1.1 5.2e-05 22.9 0.1 2.6 4 0 0 4 4 4 1 tRNA synthetases class II core domain (F) GAD PF02938.14 CEP09586.1 - 0.0054 16.9 0.0 0.053 13.8 0.0 2.4 2 1 0 2 2 2 1 GAD domain tRNA-synt_2b PF00587.25 CEP09586.1 - 0.04 13.9 0.1 0.084 12.8 0.1 1.7 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Apolipoprotein PF01442.18 CEP09587.1 - 0.00015 21.7 12.2 0.00027 20.9 12.2 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 CEP09587.1 - 0.0014 18.8 14.4 0.12 12.4 8.7 2.2 1 1 1 2 2 2 2 ATP synthase B/B' CF(0) DUF1640 PF07798.11 CEP09587.1 - 0.04 14.0 3.5 0.048 13.7 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF883 PF05957.13 CEP09587.1 - 0.042 14.4 16.2 0.81 10.3 6.1 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2884 PF11101.8 CEP09587.1 - 0.049 13.1 6.3 0.12 11.8 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) YtxH PF12732.7 CEP09587.1 - 0.071 13.7 18.2 1.4 9.5 6.4 3.1 1 1 1 2 2 2 0 YtxH-like protein WXG100 PF06013.12 CEP09587.1 - 0.083 13.1 12.5 0.11 12.7 4.5 2.7 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.15 CEP09587.1 - 0.12 11.9 5.1 0.16 11.5 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PE PF00934.20 CEP09587.1 - 0.31 11.4 4.7 0.92 9.9 1.7 2.5 1 1 0 2 2 2 0 PE family DUF5082 PF16888.5 CEP09587.1 - 0.32 11.3 11.3 1.3 9.3 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cupin_8 PF13621.6 CEP09587.1 - 0.45 10.2 6.4 0.61 9.8 6.4 1.4 1 1 0 1 1 1 0 Cupin-like domain YlqD PF11068.8 CEP09587.1 - 0.53 10.7 8.0 7.7 6.9 8.0 2.2 1 1 0 1 1 1 0 YlqD protein Prominin PF05478.11 CEP09587.1 - 0.94 7.3 2.3 4.2 5.2 2.0 1.7 1 1 1 2 2 2 0 Prominin Tape_meas_lam_C PF09718.10 CEP09587.1 - 0.98 9.6 6.3 0.27 11.4 0.4 2.6 2 2 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoO PF09769.9 CEP09587.1 - 1.6 8.7 4.7 65 3.5 4.7 2.7 1 1 0 1 1 1 0 Apolipoprotein O Phasin PF05597.11 CEP09587.1 - 2.3 8.2 12.3 1.9 8.5 2.2 2.7 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Uso1_p115_C PF04871.13 CEP09587.1 - 3.4 8.0 20.3 1.1 9.6 2.5 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3435 PF11917.8 CEP09587.1 - 3.6 6.4 8.7 6.7 5.5 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) Remorin_C PF03763.13 CEP09587.1 - 6.8 6.6 19.4 0.57 10.1 4.7 2.4 1 1 0 2 2 2 0 Remorin, C-terminal region OmpH PF03938.14 CEP09587.1 - 7.5 6.9 11.4 14 6.0 11.0 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CPSase_sm_chain PF00988.22 CEP09588.1 - 3.1e-48 162.8 0.0 4.5e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEP09588.1 - 1.9e-42 145.2 0.0 2.6e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEP09588.1 - 2.1e-05 24.4 0.3 0.35 10.6 0.0 3.0 2 1 1 3 3 3 2 Peptidase C26 DJ-1_PfpI PF01965.24 CEP09588.1 - 0.18 11.6 0.1 0.51 10.1 0.1 1.7 2 0 0 2 2 2 0 DJ-1/PfpI family Dynactin PF12455.8 CEP09589.1 - 4e-88 295.4 9.8 4e-88 295.4 9.8 6.0 6 2 1 7 7 7 1 Dynein associated protein CAP_GLY PF01302.25 CEP09589.1 - 6.4e-24 83.7 1.7 1.1e-23 83.0 1.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain Pox_A_type_inc PF04508.12 CEP09589.1 - 1.1 9.2 11.1 2.1 8.3 1.4 4.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Hydrolase_6 PF13344.6 CEP09591.1 - 5.1e-21 74.7 0.0 8.8e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP09591.1 - 1.6e-09 37.7 0.0 3.8e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP09591.1 - 1.1e-05 25.8 0.1 0.066 13.5 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP09591.1 - 0.00033 20.8 0.0 0.34 11.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF4032 PF13224.6 CEP09591.1 - 0.024 14.5 0.1 0.058 13.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4032) Hydrolase_3 PF08282.12 CEP09591.1 - 0.025 14.3 0.1 0.076 12.7 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 CEP09592.1 - 1.3e-49 168.5 0.4 1.5e-49 168.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fimbrial_PilY2 PF14481.6 CEP09593.1 - 0.028 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 ELFV_dehydrog_N PF02812.18 CEP09594.1 - 5.6e-60 200.9 0.0 1.1e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CEP09594.1 - 1.1e-55 189.0 2.3 2.6e-53 181.2 0.2 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEP09594.1 - 0.05 11.1 0.1 0.21 9.0 0.0 2.0 2 1 1 3 3 3 0 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.19 CEP09594.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1611_N PF17396.2 CEP09594.1 - 0.12 12.6 0.0 0.96 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain AdoHcyase_NAD PF00670.21 CEP09594.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M41 PF01434.18 CEP09595.1 - 1.6e-64 217.3 0.0 2.3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CEP09595.1 - 2.2e-43 147.9 0.0 5.9e-43 146.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP09595.1 - 1.3e-11 44.1 0.4 3.7e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CEP09595.1 - 2.3e-08 34.4 0.1 6.5e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CEP09595.1 - 0.0002 21.4 0.1 0.022 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP09595.1 - 0.0024 18.3 0.3 0.17 12.3 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CEP09595.1 - 0.0054 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEP09595.1 - 0.0064 15.7 0.1 0.0097 15.1 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CEP09595.1 - 0.0065 16.7 0.1 0.65 10.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CEP09595.1 - 0.032 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 CEP09595.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEP09595.1 - 0.06 13.9 0.0 3 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CEP09595.1 - 0.08 12.3 0.7 0.47 9.8 0.3 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CEP09595.1 - 0.081 13.0 0.0 0.31 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_L50 PF10501.9 CEP09595.1 - 0.12 12.5 0.8 0.27 11.4 0.8 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S AAA_19 PF13245.6 CEP09595.1 - 4.7 7.5 5.0 29 5.0 1.1 2.5 2 0 0 2 2 2 0 AAA domain FAR1 PF03101.15 CEP09596.1 - 0.00015 22.4 4.7 0.00044 20.9 2.5 2.6 2 1 0 2 2 2 1 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.15 CEP09596.1 - 0.00069 19.6 1.2 0.016 15.2 0.3 2.4 2 0 0 2 2 2 1 MuDR family transposase AFT PF08731.11 CEP09596.1 - 0.0014 19.0 2.0 0.0014 19.0 2.0 2.3 2 1 0 2 2 2 1 Transcription factor AFT Uroplakin_II PF07353.12 CEP09596.1 - 0.1 12.1 0.1 0.51 9.8 0.2 1.9 2 0 0 2 2 2 0 Uroplakin II WD40 PF00400.32 CEP09597.1 - 2e-45 151.9 23.0 1e-10 42.0 0.0 6.8 6 1 1 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CEP09597.1 - 1.6e-35 122.1 3.7 1.6e-35 122.1 3.7 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CEP09597.1 - 3.7e-10 39.9 0.1 0.036 14.4 0.0 4.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP09597.1 - 4.8e-05 22.8 0.0 0.16 11.3 0.0 3.1 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 CEP09597.1 - 0.00033 19.4 0.9 0.47 9.0 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CEP09597.1 - 0.0019 18.1 0.1 0.044 13.7 0.0 2.9 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP09597.1 - 0.052 12.5 0.2 3.7 6.4 0.0 3.4 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_1 PF00561.20 CEP09598.1 - 1.2e-30 107.0 0.0 4.8e-30 105.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP09598.1 - 2.2e-19 71.0 0.0 2.9e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP09598.1 - 1e-10 41.3 0.0 3.2e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 CEP09598.1 - 0.00012 22.4 0.0 0.0004 20.7 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Ndr PF03096.14 CEP09598.1 - 0.026 13.3 0.0 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.10 CEP09598.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Phage_int_SAM_5 PF13102.6 CEP09598.1 - 0.15 12.4 0.0 4.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Phage integrase SAM-like domain UCH PF00443.29 CEP09599.1 - 9.5e-13 48.2 0.0 3.4e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Polysacc_deac_1 PF01522.21 CEP09599.1 - 1.3e-08 34.8 0.1 6.9e-08 32.4 0.1 2.3 3 0 0 3 3 3 1 Polysaccharide deacetylase UBA PF00627.31 CEP09599.1 - 0.0019 18.0 0.3 0.0051 16.7 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF1664 PF07889.12 CEP09599.1 - 0.15 12.1 1.3 1.6 8.8 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ALO PF04030.14 CEP09600.1 - 4.5e-92 308.5 5.2 4.5e-92 308.5 5.2 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CEP09600.1 - 1.6e-28 99.2 0.0 2.3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PDT PF00800.18 CEP09601.1 - 2.1e-29 102.6 0.2 7.7e-21 74.7 0.1 2.2 2 0 0 2 2 2 2 Prephenate dehydratase CM_2 PF01817.21 CEP09601.1 - 7e-21 74.4 1.0 1.4e-20 73.4 1.0 1.5 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 CEP09601.1 - 2.2e-07 30.5 0.0 4.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain PfaD_N PF18328.1 CEP09601.1 - 0.051 13.5 0.2 0.69 9.9 0.1 2.7 3 0 0 3 3 3 0 Fatty acid synthase subunit PfaD N-terminal domain Sec3_C PF09763.9 CEP09602.1 - 3.5e-150 501.7 11.4 3.5e-150 501.7 11.4 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CEP09602.1 - 2.9e-19 69.0 0.6 7.4e-19 67.7 0.6 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH TFIIA PF03153.13 CEP09602.1 - 0.016 15.3 11.8 0.032 14.3 11.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4201 PF13870.6 CEP09602.1 - 0.019 14.7 9.8 0.012 15.4 6.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GCN5L1 PF06320.13 CEP09602.1 - 0.032 14.4 9.2 0.029 14.5 6.6 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) LIP1 PF15904.5 CEP09602.1 - 0.098 13.0 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 LKB1 serine/threonine kinase interacting protein 1 DUF1351 PF07083.11 CEP09602.1 - 0.37 10.5 12.4 0.057 13.2 4.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) Vps52 PF04129.12 CEP09602.1 - 0.68 8.6 15.2 0.046 12.5 7.0 2.9 3 1 0 3 3 3 0 Vps52 / Sac2 family Ndc1_Nup PF09531.10 CEP09602.1 - 0.76 8.4 10.3 1.2 7.7 10.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Adap_comp_sub PF00928.21 CEP09603.1 - 4.7e-31 108.1 0.0 9.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEP09603.1 - 4.3e-06 26.7 0.2 6.8e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.6 CEP09603.1 - 0.01 16.0 3.7 0.019 15.1 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LIM PF00412.22 CEP09604.1 - 6.8e-30 103.1 59.8 9.4e-11 41.8 11.3 4.9 5 0 0 5 5 5 4 LIM domain WRC PF08879.10 CEP09604.1 - 0.093 12.4 6.2 0.42 10.3 0.1 3.4 2 1 0 2 2 2 0 WRC Lsm_interact PF05391.11 CEP09604.1 - 1.1 8.9 7.8 0.11 12.1 1.7 2.4 2 0 0 2 2 2 0 Lsm interaction motif NTP_transferase PF00483.23 CEP09605.1 - 4.3e-28 98.6 0.0 6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEP09605.1 - 9.3e-10 37.9 4.7 6.7e-06 25.6 0.1 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEP09605.1 - 3.1e-08 34.1 0.0 5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CEP09605.1 - 0.0037 16.3 0.6 0.014 14.3 0.6 1.9 1 1 0 1 1 1 1 L-fucokinase Ntox30 PF15532.6 CEP09605.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 30 Nt_Gln_amidase PF09764.9 CEP09607.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal glutamine amidase zf-C2H2_10 PF16588.5 CEP09607.1 - 0.016 15.0 2.6 0.035 13.8 2.6 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 CEP09607.1 - 1.9 8.7 12.2 5.2 7.3 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle NDC10_II PF16787.5 CEP09608.1 - 1.1e-08 34.5 0.1 0.0021 17.1 0.2 3.1 2 1 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 PcfK PF14058.6 CEP09608.1 - 1.6 9.0 5.2 0.28 11.4 0.8 1.9 2 0 0 2 2 2 0 PcfK-like protein DDE_3 PF13358.6 CEP09609.1 - 3.2e-11 43.2 0.0 4.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Integrase_H2C2 PF17921.1 CEP09611.1 - 6.8e-17 61.3 0.6 1.1e-16 60.7 0.6 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Nitroreductase PF00881.24 CEP09613.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.7 2 0 0 2 2 2 0 Nitroreductase family Helitron_like_N PF14214.6 CEP09614.1 - 7.1e-29 101.4 0.1 1.5e-28 100.3 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP09614.1 - 3.9e-06 26.3 0.1 7.1e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP09614.1 - 0.00012 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP09614.1 - 0.0063 16.9 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 CEP09614.1 - 0.033 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CEP09614.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Importin_rep PF18773.1 CEP09614.1 - 0.079 12.7 0.2 0.21 11.3 0.2 1.7 1 0 0 1 1 1 0 Importin 13 repeat AAA_10 PF12846.7 CEP09614.1 - 0.08 11.9 0.1 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain DUF4116 PF13475.6 CEP09616.1 - 0.11 12.2 0.7 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) GTP_EFTU PF00009.27 CEP09619.1 - 4.1e-55 186.4 0.0 5.4e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP09619.1 - 2.8e-14 53.4 0.0 5.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEP09619.1 - 4.4e-14 52.6 0.6 4.4e-14 52.6 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEP09619.1 - 0.00019 21.5 0.3 0.005 16.9 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CEP09619.1 - 0.23 11.4 1.5 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RT_RNaseH PF17917.1 CEP09620.1 - 1.2e-28 99.4 0.0 2.7e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP09620.1 - 6.9e-28 96.6 0.2 1.7e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CEP09620.1 - 0.0042 17.1 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Pao retrotransposon peptidase HTH_Tnp_Tc3_2 PF01498.18 CEP09622.1 - 3e-10 40.2 0.2 1.1e-09 38.3 0.0 2.0 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.6 CEP09622.1 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CEP09622.1 - 6.1e-06 26.3 0.0 1.6e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP09622.1 - 0.00062 19.5 0.0 0.0033 17.2 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP09622.1 - 0.0012 19.4 0.1 0.024 15.2 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain Phage_antitermQ PF06530.12 CEP09622.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.6 2 0 0 2 2 2 0 Phage antitermination protein Q Fe_dep_repress PF01325.19 CEP09622.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_7 PF02796.15 CEP09622.1 - 0.05 13.7 0.3 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 CEP09622.1 - 0.07 13.2 0.0 1.3 9.2 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix MarR_2 PF12802.7 CEP09622.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 MarR family DDE_3 PF13358.6 CEP09623.1 - 2.4e-20 72.8 0.1 4.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 CEP09623.1 - 0.13 12.4 0.0 0.63 10.2 0.0 2.0 2 1 0 2 2 2 0 Integrase core domain PIF1 PF05970.14 CEP09624.1 - 1.4e-07 31.0 0.0 2.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Auxin_repressed PF05564.12 CEP09626.1 - 0.074 13.7 0.4 0.1 13.3 0.4 1.3 1 0 0 1 1 1 0 Dormancy/auxin associated protein L31 PF09784.9 CEP09627.1 - 4.2e-41 139.5 0.1 4.8e-41 139.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Msap1 PF17077.5 CEP09627.1 - 0.032 13.4 0.2 0.038 13.2 0.2 1.0 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 Nop52 PF05997.12 CEP09628.1 - 1.4e-67 227.7 1.0 2.3e-67 227.0 1.0 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Voldacs PF03517.13 CEP09628.1 - 0.089 12.9 6.9 0.13 12.3 6.9 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Cwf_Cwc_15 PF04889.12 CEP09628.1 - 0.39 10.4 17.0 0.62 9.7 17.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 CEP09628.1 - 1.6 7.7 16.2 7.9 5.4 13.9 2.2 2 0 0 2 2 2 0 Pes-10 RNA_pol_3_Rpc31 PF11705.8 CEP09628.1 - 2.4 8.4 18.1 3.5 7.8 18.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 CEP09628.1 - 6.6 6.2 15.3 84 2.6 15.0 2.1 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 CEP09628.1 - 9.8 5.4 20.3 3.7 6.8 16.5 1.9 2 0 0 2 2 2 0 NOA36 protein RabGAP-TBC PF00566.18 CEP09629.1 - 1.5e-48 165.3 2.2 4.2e-48 163.8 2.2 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CTNNBL PF08216.11 CEP09629.1 - 0.096 12.9 0.5 0.37 11.0 0.2 2.2 1 1 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Ribosomal_L32e PF01655.18 CEP09630.1 - 3.9e-49 165.6 0.5 4.6e-49 165.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DSPc PF00782.20 CEP09631.1 - 8e-08 32.2 1.0 6.9e-07 29.2 0.0 2.5 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEP09631.1 - 4.8e-07 30.0 0.0 5.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP09631.1 - 5.8e-07 29.3 0.0 8.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEP09631.1 - 8.2e-05 22.8 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 CEP09631.1 - 0.0075 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) GTP_EFTU PF00009.27 CEP09631.1 - 0.01 15.4 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Y_phosphatase2 PF03162.13 CEP09631.1 - 0.011 15.3 0.7 0.035 13.7 0.1 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family DUF4116 PF13475.6 CEP09631.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Rhodanese PF00581.20 CEP09631.1 - 0.033 14.7 0.1 0.089 13.3 0.0 1.8 2 1 0 2 2 2 0 Rhodanese-like domain F-box-like PF12937.7 CEP09632.1 - 0.00044 20.1 1.9 0.00091 19.1 1.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP09632.1 - 0.01 15.7 1.3 0.02 14.8 1.3 1.5 1 0 0 1 1 1 0 F-box domain DUF1440 PF07274.12 CEP09633.1 - 0.067 13.5 2.1 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) LRR_4 PF12799.7 CEP09634.1 - 0.0011 19.3 13.7 3.1 8.3 0.2 6.6 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) DUF5643 PF18705.1 CEP09634.1 - 0.09 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5643) SNF5 PF04855.12 CEP09635.1 - 1.1e-54 185.8 2.5 1.5e-26 93.7 1.0 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.6 CEP09636.1 - 4e-14 52.8 0.0 4.9e-06 26.8 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CEP09636.1 - 3.9e-12 45.3 1.1 0.079 13.3 0.0 6.7 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 CEP09636.1 - 1.9e-07 31.3 11.0 0.01 15.9 0.1 4.4 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 CEP09636.1 - 1.5e-05 25.2 0.8 0.00025 21.3 0.1 3.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 CEP09636.1 - 0.00044 19.5 1.6 0.031 13.5 0.1 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 CEP09636.1 - 0.005 17.3 0.9 7 7.3 0.0 5.1 6 0 0 6 6 6 1 HEAT-like repeat API5 PF05918.11 CEP09636.1 - 0.0096 14.8 3.6 0.031 13.1 1.4 2.8 2 1 1 3 3 3 2 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_C PF11698.8 CEP09636.1 - 0.039 14.0 3.6 0.056 13.6 0.2 3.0 3 0 0 3 3 3 0 V-ATPase subunit H RTP1_C1 PF10363.9 CEP09636.1 - 0.045 13.9 3.7 14 6.0 0.0 4.5 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 ENTH PF01417.20 CEP09636.1 - 0.052 13.6 3.5 0.44 10.6 1.8 3.2 3 0 0 3 3 3 0 ENTH domain DUF4042 PF13251.6 CEP09636.1 - 2 8.1 9.1 0.78 9.4 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) SRF-TF PF00319.18 CEP09638.1 - 2.6e-22 78.1 0.0 4.6e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PAT1 PF09770.9 CEP09638.1 - 5.3 5.2 30.4 6.5 4.9 30.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0029 PF01205.19 CEP09639.1 - 3.3e-34 117.4 0.1 7e-34 116.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CEP09639.1 - 1e-13 51.6 1.4 3.8e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 RWD domain Peroxin-13_N PF04088.13 CEP09639.1 - 0.019 15.2 0.1 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Zincin_2 PF10103.9 CEP09639.1 - 0.08 12.2 0.9 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 Zincin-like metallopeptidase CSRNP_N PF16019.5 CEP09639.1 - 0.46 10.4 1.9 0.97 9.3 1.9 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tcp11 PF05794.13 CEP09640.1 - 9.3e-51 173.3 3.7 9.3e-51 173.3 3.7 1.9 2 0 0 2 2 2 1 T-complex protein 11 Sensor PF13796.6 CEP09641.1 - 0.035 14.2 2.9 0.055 13.5 0.2 2.5 3 0 0 3 3 3 0 Putative sensor Adeno_E3B PF03376.14 CEP09641.1 - 0.081 13.2 2.1 0.13 12.6 0.4 2.1 2 0 0 2 2 2 0 Adenovirus E3B protein DC_STAMP PF07782.13 CEP09641.1 - 0.27 11.1 6.4 23 4.7 3.7 3.2 2 1 0 2 2 2 0 DC-STAMP-like protein AI-2E_transport PF01594.16 CEP09641.1 - 0.45 9.6 10.9 0.18 10.9 4.6 2.7 3 0 0 3 3 3 0 AI-2E family transporter SET PF00856.28 CEP09642.1 - 1.9e-11 44.6 0.2 4.8e-11 43.3 0.1 1.7 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEP09642.1 - 1.1e-05 25.4 12.4 1.1e-05 25.4 12.4 2.3 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CEP09642.1 - 1.6 9.1 10.8 4.2 7.7 10.8 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF4690 PF15756.5 CEP09643.1 - 0.0049 17.5 0.2 0.024 15.2 0.1 2.1 2 0 0 2 2 2 1 Small Novel Rich in Cartilage DUF4711 PF15829.5 CEP09643.1 - 0.0049 16.8 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4711) Mid2 PF04478.12 CEP09643.1 - 0.079 12.8 0.5 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF4366 PF14283.6 CEP09643.1 - 0.082 13.0 0.5 0.36 10.9 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) TMEM154 PF15102.6 CEP09643.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family FixS PF03597.15 CEP09643.1 - 2.9 7.7 5.3 5.5 6.8 5.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF3425 PF11905.8 CEP09644.1 - 6e-13 48.8 1.6 3.7e-12 46.3 1.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEP09644.1 - 7.5e-06 26.0 6.5 7.5e-06 26.0 6.5 2.5 3 0 0 3 3 3 1 bZIP transcription factor Helicase_Sgs1 PF11408.8 CEP09644.1 - 0.01 15.9 2.7 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Sgs1 RecQ helicase DUF5572 PF17733.1 CEP09644.1 - 0.035 14.0 0.2 0.15 11.9 0.2 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5572) Glutaredoxin2_C PF04399.13 CEP09644.1 - 0.045 13.6 1.5 0.099 12.5 0.2 2.3 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Phlebovirus_NSM PF07246.11 CEP09644.1 - 0.76 9.1 5.8 0.58 9.5 0.3 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF3425 PF11905.8 CEP09645.1 - 1.4e-08 34.7 0.2 9.3e-08 32.1 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 CEP09645.1 - 0.0022 18.1 16.0 0.096 12.8 1.2 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 CEP09645.1 - 0.094 12.8 18.1 0.43 10.7 17.4 2.3 1 1 0 1 1 1 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 CEP09645.1 - 3.9 7.7 9.5 1 9.6 3.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fungal_trans PF04082.18 CEP09646.1 - 2.1e-20 72.9 0.5 5.8e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP09646.1 - 9.9e-11 41.6 11.9 9.9e-11 41.6 11.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD_C_2 PF13538.6 CEP09650.1 - 1.4e-11 44.0 0.0 4.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP09650.1 - 4.3e-06 25.0 0.0 5.3e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CEP09650.1 - 5.6e-05 23.0 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.23 CEP09651.1 - 2.7e-07 30.3 2.4 5.3e-07 29.4 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEP09651.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 CEP09651.1 - 0.036 14.0 1.8 0.065 13.2 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CEP09651.1 - 0.051 13.3 2.4 0.1 12.3 2.4 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CEP09651.1 - 0.13 12.0 1.2 0.25 11.1 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CEP09652.1 - 6.6e-06 26.0 7.7 0.00078 19.4 1.6 2.5 2 0 0 2 2 2 2 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 CEP09652.1 - 0.012 15.6 2.1 0.012 15.6 2.1 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HNH PF01844.23 CEP09652.1 - 0.016 15.4 0.4 0.016 15.4 0.4 2.3 2 0 0 2 2 2 0 HNH endonuclease zinc-ribbons_6 PF07191.12 CEP09652.1 - 0.37 10.8 6.9 1.2 9.2 0.4 2.3 1 1 1 2 2 2 0 zinc-ribbons Prok-RING_4 PF14447.6 CEP09652.1 - 1.7 8.5 8.3 0.59 10.0 0.8 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DciA PF05258.12 CEP09653.1 - 0.064 13.7 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA zf-CCHC_3 PF13917.6 CEP09654.1 - 0.0025 17.7 3.8 0.0025 17.7 3.8 1.9 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 CEP09654.1 - 0.0025 17.8 2.8 0.0025 17.8 2.8 1.6 2 0 0 2 2 2 1 Zinc knuckle HypA PF01155.19 CEP09654.1 - 0.11 12.5 1.4 3.1 7.9 1.0 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_10 PF16588.5 CEP09654.1 - 8.3 6.2 8.1 3.7 7.4 2.8 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 CEP09655.1 - 0.00084 19.3 7.5 0.025 14.7 1.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-BED PF02892.15 CEP09655.1 - 0.019 15.0 6.0 0.38 10.8 1.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-RING_7 PF02591.15 CEP09655.1 - 0.11 12.8 4.0 0.21 11.8 0.4 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-CCHC_4 PF14392.6 CEP09655.1 - 0.15 11.8 10.5 1.3 8.8 1.2 2.2 2 0 0 2 2 2 0 Zinc knuckle CpXC PF14353.6 CEP09655.1 - 0.16 12.0 2.0 0.43 10.6 0.1 2.0 1 1 0 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 CEP09655.1 - 0.23 11.5 6.2 2.7 8.0 0.3 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 CEP09655.1 - 1.1 9.3 6.3 5.8 7.0 6.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-CCHC_6 PF15288.6 CEP09655.1 - 3.1 7.7 10.8 1.2 9.1 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP09655.1 - 9.6 6.0 16.2 5.6 6.8 2.8 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger Apq12 PF12716.7 CEP09656.1 - 1.1 9.2 11.4 1.8 8.6 11.4 1.3 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Hid1 PF12722.7 CEP09657.1 - 4.3e-213 709.9 8.9 4.8e-213 709.7 8.9 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CEP09657.1 - 1.1e-104 351.1 3.2 1.4e-104 350.8 3.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Homeodomain PF00046.29 CEP09658.1 - 3e-15 55.8 6.3 3e-15 55.8 6.3 1.7 2 0 0 2 2 2 1 Homeodomain Osmo_MPGsynth PF09488.10 CEP09658.1 - 0.0014 17.5 1.5 0.0017 17.1 1.5 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Homeobox_KN PF05920.11 CEP09658.1 - 0.017 15.0 0.2 0.055 13.4 0.2 2.0 1 0 0 1 1 1 0 Homeobox KN domain Phage_terminase PF10668.9 CEP09658.1 - 0.056 13.5 1.5 0.11 12.5 1.5 1.5 1 0 0 1 1 1 0 Phage terminase small subunit Neur_chan_memb PF02932.16 CEP09658.1 - 1.6 8.7 5.4 2.1 8.4 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.26 CEP09660.1 - 5.5e-06 26.5 10.4 0.00088 19.6 1.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP09660.1 - 3.4e-05 24.3 9.3 0.025 15.4 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP09660.1 - 8.1e-05 22.9 3.8 8.1e-05 22.9 3.8 3.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 CEP09660.1 - 0.012 15.9 4.0 3.2 8.3 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP09660.1 - 0.012 15.8 2.6 2.3 8.6 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CEP09660.1 - 2.2 8.3 12.7 0.74 9.8 3.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Phosphodiest PF01663.22 CEP09661.1 - 1.8e-07 31.1 2.8 3.8e-06 26.7 0.2 2.8 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CEP09661.1 - 0.013 14.9 0.6 0.047 13.1 0.6 1.7 1 1 0 1 1 1 0 Metalloenzyme superfamily DUF2231 PF09990.9 CEP09661.1 - 0.034 14.6 7.1 0.063 13.7 1.9 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Ribosomal_L1 PF00687.21 CEP09662.1 - 4.1e-38 131.2 6.8 4.1e-38 131.2 6.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PAP2_C PF14360.6 CEP09663.1 - 4.5e-16 59.1 10.0 4.5e-16 59.1 10.0 2.4 4 0 0 4 4 4 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CEP09663.1 - 0.0014 18.4 6.7 0.0014 18.4 6.7 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CEP09663.1 - 0.12 12.1 9.4 0.3 10.8 9.4 1.8 1 1 0 1 1 1 0 PAP2 superfamily PhyH PF05721.13 CEP09665.1 - 1.9e-48 165.5 0.0 2.3e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Forkhead PF00250.18 CEP09666.1 - 9.6e-35 118.7 0.1 3.1e-34 117.1 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain Sugar_tr PF00083.24 CEP09667.1 - 1.3e-16 60.5 13.8 1.6e-16 60.3 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP09667.1 - 0.0035 16.3 11.3 0.011 14.7 11.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Det1 PF09737.9 CEP09668.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 TGFb_propeptide PF00688.18 CEP09669.1 - 0.14 11.9 1.5 0.21 11.3 1.5 1.3 1 0 0 1 1 1 0 TGF-beta propeptide DAO PF01266.24 CEP09670.1 - 1.1e-43 150.2 0.0 1.3e-43 149.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEP09670.1 - 7.4e-07 29.3 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP09670.1 - 0.00071 18.9 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP09670.1 - 0.0033 16.6 0.0 0.29 10.2 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 CEP09670.1 - 0.0061 15.3 0.0 0.72 8.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 CEP09670.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CEP09670.1 - 0.0091 16.0 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CEP09670.1 - 0.16 11.0 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FGGY_N PF00370.21 CEP09671.1 - 4.3e-70 236.1 0.1 7.9e-70 235.2 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEP09671.1 - 2.9e-69 232.8 0.5 4.7e-69 232.1 0.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cation_efflux PF01545.21 CEP09671.1 - 5.3e-40 137.3 6.7 9.6e-40 136.4 6.7 1.3 1 0 0 1 1 1 1 Cation efflux family BcrAD_BadFG PF01869.20 CEP09671.1 - 0.034 13.6 0.0 0.81 9.1 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TMEM141 PF15110.6 CEP09671.1 - 0.045 14.3 0.8 1.6 9.4 0.2 2.6 2 0 0 2 2 2 0 TMEM141 protein family DUF2162 PF09930.9 CEP09671.1 - 0.16 11.4 4.1 0.47 9.8 4.1 1.7 2 0 0 2 2 2 0 Predicted transporter (DUF2162) DUF4010 PF13194.6 CEP09671.1 - 7 6.3 10.2 7.9 6.1 5.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4010) DUF1295 PF06966.12 CEP09672.1 - 2.6e-42 145.0 5.2 3.6e-42 144.5 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Importin_rep_4 PF18808.1 CEP09674.1 - 2.3e-33 114.4 6.8 3.5e-32 110.6 0.2 4.8 6 0 0 6 6 4 1 Importin repeat Importin_rep_6 PF18829.1 CEP09674.1 - 6.7e-18 64.8 1.2 8e-17 61.3 0.0 3.1 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 CEP09674.1 - 2.1e-17 63.5 3.2 4.8e-05 23.9 0.0 7.3 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CEP09674.1 - 6.7e-17 61.7 12.0 0.0007 19.9 0.0 9.1 5 3 5 11 11 11 5 HEAT repeats HEAT_EZ PF13513.6 CEP09674.1 - 1.8e-16 60.3 14.5 1.4e-06 28.7 0.0 10.6 10 1 2 12 12 10 3 HEAT-like repeat HEAT PF02985.22 CEP09674.1 - 5.1e-15 54.3 13.5 0.0076 16.4 0.0 10.8 12 0 0 12 12 11 3 HEAT repeat DUF3385 PF11865.8 CEP09674.1 - 1.5e-11 44.5 6.3 0.067 13.1 0.5 8.5 5 2 3 8 8 8 5 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CEP09674.1 - 4.5e-09 35.9 8.0 0.0043 16.2 0.2 6.7 5 3 1 7 7 7 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CEP09674.1 - 1.1e-08 34.9 2.3 0.21 11.1 0.0 5.3 5 1 1 6 6 6 3 CLASP N terminal RTP1_C1 PF10363.9 CEP09674.1 - 8.2e-05 22.8 2.7 0.061 13.5 0.3 5.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 CEP09674.1 - 8.5e-05 22.4 1.8 0.083 12.6 0.1 4.8 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 CEP09674.1 - 0.0055 16.8 12.1 0.011 15.7 0.3 4.9 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 CEP09674.1 - 0.0059 15.8 2.1 0.014 14.5 0.0 2.6 2 1 0 2 2 2 1 Dopey, N-terminal Importin_rep_5 PF18816.1 CEP09674.1 - 0.014 15.7 0.0 0.014 15.7 0.0 3.0 3 0 0 3 3 2 0 Importin repeat V-ATPase_H_N PF03224.14 CEP09674.1 - 0.015 14.6 5.4 0.26 10.5 0.1 3.5 2 1 0 3 3 3 0 V-ATPase subunit H CDT1_C PF16679.5 CEP09674.1 - 0.021 15.3 2.7 6.5 7.3 0.2 3.9 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Arm PF00514.23 CEP09674.1 - 0.035 14.2 12.0 1.6 8.9 0.0 6.3 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat Tmemb_cc2 PF10267.9 CEP09675.1 - 0.0016 17.7 11.1 0.0016 17.7 11.1 1.9 2 1 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein CorA PF01544.18 CEP09675.1 - 0.0027 17.1 9.6 0.0057 16.0 9.6 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 CEP09675.1 - 0.45 10.0 12.0 0.35 10.4 8.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 CEP09675.1 - 1.1 8.3 14.4 0.094 11.8 8.9 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 CEP09675.1 - 1.1 9.5 12.0 0.055 13.8 3.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF948 PF06103.11 CEP09675.1 - 2.4 8.5 4.2 3.9 7.8 0.0 3.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Plk4_PB2 PF18409.1 CEP09675.1 - 4.7 8.0 9.2 14 6.4 5.4 3.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF4407 PF14362.6 CEP09675.1 - 5 6.4 12.5 0.36 10.1 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WD40 PF00400.32 CEP09676.1 - 1.1e-15 57.7 11.0 0.056 14.3 0.1 7.1 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09676.1 - 1.7e-10 41.1 0.1 0.0023 18.2 0.0 5.1 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP09676.1 - 0.0016 17.8 0.2 0.24 10.7 0.1 2.7 1 1 1 2 2 2 2 WD40-like domain Cytochrom_D1 PF02239.16 CEP09676.1 - 0.0051 15.4 0.3 0.15 10.6 0.1 2.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain RR_TM4-6 PF06459.12 CEP09676.1 - 0.029 14.2 4.3 0.041 13.7 4.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 CEP09676.1 - 0.54 10.3 18.1 0.77 9.8 18.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TSGP1 PF07771.11 CEP09676.1 - 1.5 9.0 10.1 2.6 8.2 10.1 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 CDC45 PF02724.14 CEP09676.1 - 2.3 6.4 11.8 3.8 5.7 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RhoGAP PF00620.27 CEP09677.1 - 1.9e-50 170.6 0.1 5.2e-50 169.2 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CEP09677.1 - 3.9e-08 33.1 3.7 3.9e-08 33.1 3.7 3.5 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 CEP09677.1 - 7.4e-07 29.3 7.3 7.4e-07 29.3 7.3 2.5 2 0 0 2 2 2 1 LIM domain C1_2 PF03107.16 CEP09677.1 - 0.0047 17.2 2.8 0.0047 17.2 2.8 2.6 4 0 0 4 4 3 1 C1 domain ADSL_C PF10397.9 CEP09677.1 - 0.24 12.0 0.6 1.6 9.4 0.3 2.5 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF3848 PF12959.7 CEP09677.1 - 0.33 11.0 5.3 0.12 12.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Tup_N PF08581.10 CEP09677.1 - 0.48 10.8 13.3 1.3 9.4 2.1 3.3 4 0 0 4 4 3 0 Tup N-terminal CENP-F_leu_zip PF10473.9 CEP09677.1 - 0.99 9.4 17.5 0.24 11.4 2.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 CEP09677.1 - 1.5 9.3 10.5 0.37 11.3 1.3 3.1 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TMF_TATA_bd PF12325.8 CEP09677.1 - 2.5 8.3 22.2 1 9.6 2.6 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 CEP09677.1 - 6.8 7.1 16.9 9.7 6.6 0.4 3.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ENTH PF01417.20 CEP09679.1 - 1.3e-45 154.5 0.1 2.3e-45 153.7 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CEP09679.1 - 9.8e-05 21.5 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CEP09679.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 VHS domain Cpn60_TCP1 PF00118.24 CEP09680.1 - 4.4e-156 520.3 15.7 5.2e-156 520.1 15.7 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PH PF00169.29 CEP09680.1 - 2.5e-06 28.0 0.0 6.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CEP09680.1 - 0.016 15.6 0.0 0.054 13.9 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 CEP09680.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Phi_1 PF04674.12 CEP09681.1 - 0.081 12.2 0.0 0.082 12.2 0.0 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region WD40 PF00400.32 CEP09682.1 - 5.9e-09 36.4 2.9 0.042 14.7 0.4 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40_like PF17005.5 CEP09682.1 - 0.081 12.2 0.1 0.2 11.0 0.0 1.7 1 1 1 2 2 2 0 WD40-like domain Tetraspanin PF00335.20 CEP09682.1 - 0.081 12.6 0.0 7.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Tetraspanin family Ribosomal_L22e PF01776.17 CEP09683.1 - 2.1e-49 166.4 2.0 2.5e-49 166.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family LRR_6 PF13516.6 CEP09685.1 - 2.1e-09 36.7 14.5 0.029 14.4 0.0 6.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 CEP09685.1 - 2.5e-09 37.2 14.3 0.00039 20.8 0.7 6.5 3 2 5 8 8 8 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP09685.1 - 3.7e-06 26.7 6.0 2.1 9.2 0.0 7.4 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 CEP09685.1 - 8.5e-05 22.2 13.7 0.018 14.8 0.5 6.3 5 2 1 6 6 6 1 Leucine rich repeat Rav1p_C PF12234.8 CEP09685.1 - 1.7 7.0 4.2 2.2 6.6 4.2 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal NOA36 PF06524.12 CEP09685.1 - 7.6 5.8 14.4 14 4.9 14.4 1.4 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 CEP09685.1 - 8.9 5.3 20.9 14 4.6 20.9 1.3 1 0 0 1 1 1 0 Pes-10 DUF4422 PF14393.6 CEP09686.1 - 0.037 13.9 2.2 0.048 13.5 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) PI3K_1B_p101 PF10486.9 CEP09686.1 - 0.23 9.2 13.7 0.26 9.0 13.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 CEP09686.1 - 1.4 5.9 13.8 1.6 5.8 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Snf7 PF03357.21 CEP09687.1 - 6.4e-13 48.7 16.9 8.8e-13 48.2 16.9 1.3 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CEP09687.1 - 0.00066 19.6 2.4 0.00095 19.1 2.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RelB_N PF18506.1 CEP09687.1 - 0.069 13.0 0.4 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain VTC PF09359.10 CEP09688.1 - 3.6e-26 92.2 0.4 5e-26 91.7 0.4 1.2 1 0 0 1 1 1 1 VTC domain DUF1534 PF07551.11 CEP09688.1 - 0.15 11.8 0.7 0.44 10.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) ChaC PF04752.12 CEP09689.1 - 8.5e-67 224.7 0.0 1e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 CEP09689.1 - 0.0096 16.5 0.3 0.015 15.9 0.3 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4038 PF13204.6 CEP09689.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Zip PF02535.22 CEP09690.1 - 1.2e-53 182.6 12.9 1.7e-53 182.0 12.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter PAP_central PF04928.17 CEP09692.1 - 1.4e-40 138.8 0.0 2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEP09692.1 - 1.1e-11 44.6 0.3 1.8e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEP09692.1 - 3.2e-05 24.1 0.0 9.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain GPI-anchored PF10342.9 CEP09693.1 - 3.6e-15 56.5 1.3 6.4e-15 55.7 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Melittin PF01372.17 CEP09693.1 - 0.042 13.8 0.2 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Melittin DUF3446 PF11928.8 CEP09693.1 - 4.5 7.7 11.5 0.77 10.1 6.4 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain G-patch PF01585.23 CEP09694.1 - 1.2e-16 60.3 0.5 3.2e-16 58.9 0.5 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP09694.1 - 2.7e-08 33.8 0.7 2.7e-08 33.8 0.7 2.7 3 1 0 3 3 3 1 G-patch domain DUF4661 PF15576.6 CEP09694.1 - 0.39 10.6 4.9 0.28 11.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Hpt PF01627.23 CEP09695.1 - 8e-12 45.3 0.8 1.7e-11 44.2 0.8 1.6 1 1 0 1 1 1 1 Hpt domain Protocadherin PF08374.11 CEP09695.1 - 1.6 8.7 6.9 0.95 9.4 1.2 2.5 2 1 0 2 2 2 0 Protocadherin FAS_N PF17828.1 CEP09695.1 - 2.9 7.9 7.9 1 9.4 1.6 2.5 1 1 2 3 3 3 0 N-terminal domain in fatty acid synthase subunit beta Aminotran_3 PF00202.21 CEP09696.1 - 1.8e-121 405.7 0.0 3.5e-121 404.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-III Use1 PF09753.9 CEP09696.1 - 6e-22 78.6 12.4 6e-22 78.6 12.4 2.3 2 0 0 2 2 2 1 Membrane fusion protein Use1 BLOC1_2 PF10046.9 CEP09696.1 - 4.1e-14 52.6 26.3 2e-10 40.8 6.2 5.1 4 1 1 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aminotran_1_2 PF00155.21 CEP09696.1 - 0.0046 16.2 0.0 0.0046 16.2 0.0 2.1 3 0 0 3 3 3 1 Aminotransferase class I and II DUF2999 PF11212.8 CEP09696.1 - 0.014 15.7 1.4 0.095 13.0 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) DUF4407 PF14362.6 CEP09696.1 - 2.9 7.2 10.0 0.13 11.6 3.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) RhoGEF PF00621.20 CEP09697.1 - 8.7e-28 97.8 2.1 1.5e-27 97.0 2.1 1.4 1 0 0 1 1 1 1 RhoGEF domain TPR_2 PF07719.17 CEP09698.1 - 1.8e-17 62.0 0.9 0.0073 16.3 0.1 5.4 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEP09698.1 - 5.4e-16 57.7 1.2 0.0021 17.8 0.1 5.3 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09698.1 - 3e-13 48.9 0.5 0.075 13.3 0.1 5.2 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP09698.1 - 1.9e-12 46.7 0.1 0.00015 21.3 0.0 3.6 2 2 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CEP09698.1 - 1.4e-10 41.3 1.7 0.00013 22.2 0.2 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP09698.1 - 3.7e-10 40.2 0.3 8.1e-06 26.3 0.1 3.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP09698.1 - 7.1e-10 38.6 0.4 0.0038 17.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP09698.1 - 6.5e-08 32.7 0.2 0.078 13.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP09698.1 - 7.9e-08 31.8 0.1 0.014 15.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP09698.1 - 2.4e-07 31.0 0.0 0.26 12.2 0.0 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP09698.1 - 1.3e-06 28.9 0.0 0.0083 16.8 0.0 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CEP09698.1 - 0.00035 20.8 0.2 0.14 12.5 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP09698.1 - 0.00042 20.1 1.2 0.57 10.1 0.1 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP09698.1 - 0.0035 17.5 0.1 0.0077 16.4 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEP09698.1 - 0.0049 16.1 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Paf67 PF10255.9 CEP09698.1 - 0.1 11.6 0.1 0.88 8.5 0.1 1.9 1 1 1 2 2 2 0 RNA polymerase I-associated factor PAF67 NSF PF02071.20 CEP09698.1 - 0.16 12.8 0.3 3.3 8.9 0.0 3.3 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat Sec15 PF04091.12 CEP09699.1 - 3.1e-103 345.5 8.7 6.2e-103 344.5 8.7 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CEP09699.1 - 0.0012 18.9 0.1 0.0012 18.9 0.1 3.8 4 1 1 5 5 5 1 Vps51/Vps67 COG2 PF06148.11 CEP09699.1 - 0.0063 16.6 4.1 0.0063 16.6 4.1 3.2 3 1 1 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CEP09699.1 - 0.013 15.4 1.7 0.077 12.9 1.7 2.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FlbT PF07378.11 CEP09699.1 - 0.24 11.5 3.7 1.6 8.8 0.4 3.7 4 0 0 4 4 4 0 Flagellar protein FlbT Med2 PF11214.8 CEP09699.1 - 0.3 11.3 4.8 8.7 6.6 0.8 3.5 2 1 1 3 3 3 0 Mediator complex subunit 2 COG5 PF10392.9 CEP09699.1 - 0.32 11.2 6.6 0.17 12.0 0.7 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF2203 PF09969.9 CEP09699.1 - 0.4 11.4 5.7 4.2 8.1 0.2 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 CEP09699.1 - 0.94 9.7 15.3 5.1 7.3 6.2 3.6 2 1 0 3 3 3 0 Flagellar FliJ protein BLI1 PF17324.2 CEP09699.1 - 3 8.5 7.8 17 6.2 0.1 3.9 3 1 0 4 4 4 0 BLOC-1 interactor 1 DnaJ PF00226.31 CEP09700.1 - 3.7e-10 39.8 0.9 8.7e-10 38.6 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain zf-CCCH PF00642.24 CEP09701.1 - 0.0019 18.1 2.7 0.0035 17.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEP09701.1 - 0.015 16.0 5.0 0.048 14.4 5.0 1.8 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CEP09701.1 - 0.029 14.4 3.7 0.051 13.6 3.7 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 CEP09701.1 - 0.042 13.7 2.1 0.07 13.0 2.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Med26 PF08711.11 CEP09701.1 - 0.1 12.7 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain MFS_1 PF07690.16 CEP09702.1 - 1.5e-37 129.4 61.5 1.6e-30 106.2 37.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEP09702.1 - 8.4e-06 24.6 10.7 8.4e-06 24.6 10.7 2.8 1 1 1 3 3 3 3 MFS/sugar transport protein Peptidase_M56 PF05569.11 CEP09702.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 RhoGEF PF00621.20 CEP09703.1 - 2.7e-39 135.3 3.1 4.8e-39 134.5 3.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CEP09703.1 - 2.5e-24 85.9 2.0 4.9e-24 85.0 0.6 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain CDC24 PF06395.11 CEP09703.1 - 4.9e-17 62.0 2.5 2.1e-07 31.1 0.4 2.7 1 1 1 2 2 2 2 CDC24 Calponin PB1 PF00564.24 CEP09703.1 - 3.8e-14 52.4 1.0 8.5e-14 51.3 0.1 2.1 2 0 0 2 2 2 1 PB1 domain PH PF00169.29 CEP09703.1 - 1.7e-05 25.2 0.2 4.4e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 PH domain Phage_int_SAM_4 PF13495.6 CEP09703.1 - 0.098 13.1 1.0 23 5.5 0.2 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Sec5 PF15469.6 CEP09703.1 - 0.32 10.8 8.1 0.23 11.2 0.6 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 OrfB_Zn_ribbon PF07282.11 CEP09706.1 - 0.00091 19.1 0.2 0.0021 18.0 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RuvX PF03652.15 CEP09706.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Glyco_hydro_3 PF00933.21 CEP09707.1 - 2.9e-67 227.3 0.1 3.8e-67 226.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CEP09707.1 - 8.4e-37 127.1 0.0 1.5e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CEP09707.1 - 2.9e-09 36.9 0.0 5.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RNase_PH_C PF03725.15 CEP09707.1 - 0.002 18.1 0.2 0.0082 16.2 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WHEP-TRS PF00458.20 CEP09707.1 - 0.017 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 WHEP-TRS domain CAF1 PF04857.20 CEP09708.1 - 2.2e-84 283.4 1.6 2.2e-84 283.4 1.6 1.7 2 0 0 2 2 2 1 CAF1 family ribonuclease HSCB_C PF07743.13 CEP09709.1 - 0.0038 17.7 3.3 0.0077 16.7 2.0 2.2 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain Mito_carr PF00153.27 CEP09710.1 - 3.8e-31 106.9 1.2 8.6e-20 70.5 0.1 2.5 2 2 0 2 2 2 2 Mitochondrial carrier protein AAA PF00004.29 CEP09712.1 - 5.6e-43 146.5 0.0 9.3e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CEP09712.1 - 1e-29 102.3 0.3 4.9e-29 100.1 0.2 2.3 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CEP09712.1 - 8.7e-10 38.2 0.0 3.1e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain MIT PF04212.18 CEP09712.1 - 1.5e-05 24.9 1.9 4.2e-05 23.5 1.9 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 CEP09712.1 - 2.1e-05 25.0 0.0 0.00025 21.5 0.0 2.2 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CEP09712.1 - 2.1e-05 24.6 0.0 0.00014 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP09712.1 - 3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEP09712.1 - 6.8e-05 23.2 0.1 0.016 15.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEP09712.1 - 9.6e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CEP09712.1 - 0.00011 22.6 0.2 0.01 16.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase DUF815 PF05673.13 CEP09712.1 - 0.00019 20.7 0.0 0.0013 18.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CEP09712.1 - 0.00024 21.1 0.0 0.00075 19.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 CEP09712.1 - 0.00033 20.0 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CEP09712.1 - 0.00046 20.7 0.1 0.002 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CEP09712.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CEP09712.1 - 0.0027 17.9 0.0 0.0069 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP09712.1 - 0.0041 16.9 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEP09712.1 - 0.012 15.2 0.1 0.76 9.3 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEP09712.1 - 0.013 15.9 0.0 0.045 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEP09712.1 - 0.037 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PPV_E1_C PF00519.17 CEP09712.1 - 0.037 12.9 0.5 3.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase NACHT PF05729.12 CEP09712.1 - 0.037 13.9 0.0 0.51 10.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 CEP09712.1 - 0.043 13.3 0.0 0.18 11.3 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 CEP09712.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 CEP09712.1 - 0.063 12.6 0.0 5.9 6.2 0.0 2.4 1 1 0 2 2 2 0 KaiC ATPase_2 PF01637.18 CEP09712.1 - 0.071 13.0 0.2 1.6 8.6 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CEP09712.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CEP09712.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 CEP09712.1 - 0.1 11.9 0.1 2.4 7.4 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CEP09712.1 - 0.12 12.9 0.1 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter CPT PF07931.12 CEP09712.1 - 0.16 11.8 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TPR_1 PF00515.28 CEP09712.1 - 0.2 11.6 1.9 1.8 8.5 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat U-box PF04564.15 CEP09714.1 - 2.3e-07 30.9 0.1 7.3e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 CEP09714.1 - 5.1e-07 29.9 12.2 5.1e-07 29.9 12.2 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP09714.1 - 5.8e-07 29.2 13.7 5.8e-07 29.2 13.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP09714.1 - 7.8e-07 28.9 11.3 7.8e-07 28.9 11.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.6 CEP09714.1 - 5.7e-05 22.8 7.1 0.00013 21.7 7.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEP09714.1 - 0.00016 21.6 1.4 0.00044 20.2 1.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEP09714.1 - 0.00091 19.1 0.2 0.00091 19.1 0.2 2.0 2 0 0 2 2 2 1 Zinc knuckle Prok-RING_4 PF14447.6 CEP09714.1 - 0.0013 18.5 11.5 0.0013 18.5 11.5 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CEP09714.1 - 0.0021 18.0 12.5 0.0021 18.0 12.5 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP09714.1 - 0.0071 16.4 9.1 0.017 15.1 9.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CEP09714.1 - 0.0081 16.4 8.5 0.022 15.0 8.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CEP09714.1 - 0.017 15.2 8.2 0.041 14.0 8.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CEP09714.1 - 0.076 12.9 3.7 0.13 12.2 3.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 CEP09714.1 - 4.6 7.2 21.4 0.07 13.0 14.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP09714.1 - 4.9 7.4 18.0 0.45 10.7 13.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING NARG2_C PF10505.9 CEP09715.1 - 2.1e-20 73.1 0.0 3.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus RT_RNaseH PF17917.1 CEP09716.1 - 2.9e-38 130.4 0.1 7.3e-38 129.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP09716.1 - 4.2e-36 123.0 0.0 1.1e-35 121.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP09716.1 - 2.9e-23 82.6 0.0 5.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP09716.1 - 2e-17 63.0 0.1 4.3e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP09716.1 - 7.3e-16 57.8 2.1 2.1e-15 56.4 2.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP09716.1 - 3.8e-15 56.1 0.0 9.7e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 CEP09716.1 - 7.1e-07 29.4 0.5 2.3e-05 24.6 0.1 3.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP09716.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-H2C2 PF09337.10 CEP09716.1 - 6.4e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger E1-E2_ATPase PF00122.20 CEP09717.1 - 9.8e-50 168.6 4.1 1.3e-49 168.2 0.2 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CEP09717.1 - 4e-14 52.1 0.0 1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CEP09717.1 - 8e-14 52.4 0.8 4e-13 50.1 0.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP09717.1 - 1.6e-05 24.8 0.3 3.2e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP09717.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HTH_Tnp_Tc3_2 PF01498.18 CEP09718.1 - 6e-10 39.2 0.1 1.2e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CEP09718.1 - 2.7e-07 30.5 0.4 5.7e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Uso1_p115_head PF04869.14 CEP09719.1 - 1.1e-76 257.9 0.0 2.5e-76 256.8 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CEP09719.1 - 4.5e-09 36.7 28.0 1.9e-08 34.7 28.0 2.1 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 CEP09719.1 - 1.6e-07 31.1 0.1 6.6e-07 29.2 0.1 2.0 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor FlxA PF14282.6 CEP09719.1 - 0.0075 16.2 18.4 0.039 13.9 16.7 2.6 1 1 1 2 2 2 1 FlxA-like protein PI3K_P85_iSH2 PF16454.5 CEP09719.1 - 0.008 15.8 2.2 0.008 15.8 2.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RTP1_C1 PF10363.9 CEP09719.1 - 0.0097 16.1 0.7 1.9 8.7 0.1 3.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 AAA_13 PF13166.6 CEP09719.1 - 0.02 13.6 14.7 0.034 12.8 14.7 1.3 1 0 0 1 1 1 0 AAA domain Zein PF01559.16 CEP09719.1 - 0.045 13.4 2.7 0.058 13.0 0.0 2.1 2 0 0 2 2 2 0 Zein seed storage protein Macoilin PF09726.9 CEP09719.1 - 0.049 12.2 9.7 0.07 11.7 9.7 1.1 1 0 0 1 1 1 0 Macoilin family TMPIT PF07851.13 CEP09719.1 - 0.78 8.9 9.6 2 7.6 8.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein SF1-HH PF16275.5 CEP09719.1 - 0.8 10.1 4.7 1.5 9.2 1.2 2.6 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain DUF4407 PF14362.6 CEP09719.1 - 0.81 9.0 11.2 1.6 8.0 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CEP09719.1 - 0.84 8.5 16.7 1.8 7.4 16.7 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 CEP09719.1 - 1.1 9.7 14.3 2.5 8.5 14.3 1.6 1 0 0 1 1 1 0 Fez1 CENP-H PF05837.12 CEP09719.1 - 2.3 8.6 12.4 7.9 6.9 12.3 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF641 PF04859.12 CEP09719.1 - 2.3 8.5 13.3 1.5 9.2 2.2 2.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 CEP09719.1 - 5.3 4.8 9.8 10 3.9 9.8 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSN5_C PF18323.1 CEP09719.1 - 5.6 8.0 7.1 3.1 8.8 4.2 2.1 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF4094 PF13334.6 CEP09719.1 - 8.9 6.8 6.7 46 4.5 6.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) FlaC_arch PF05377.11 CEP09719.1 - 10 6.6 13.6 7.1 7.1 0.8 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AAA_5 PF07728.14 CEP09720.1 - 5.5e-129 424.9 0.3 7.9e-28 97.2 0.0 9.1 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CEP09720.1 - 4.1e-53 178.1 4.7 1.1e-18 67.3 0.0 6.5 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 CEP09720.1 - 4e-35 120.1 0.3 5.2e-34 116.5 0.0 3.1 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 CEP09720.1 - 3.8e-33 114.1 0.0 4.5e-08 33.0 0.0 6.8 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CEP09720.1 - 2e-28 99.5 0.0 0.0002 21.8 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEP09720.1 - 1.7e-26 92.8 2.2 1.8e-05 24.3 0.0 6.6 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 CEP09720.1 - 4.2e-25 89.1 6.4 0.00029 21.2 0.1 8.7 6 2 0 6 6 6 6 AAA ATPase domain AAA_18 PF13238.6 CEP09720.1 - 3.7e-23 82.5 0.9 0.0031 18.1 0.0 8.0 6 0 0 6 6 6 5 AAA domain AAA_22 PF13401.6 CEP09720.1 - 4.1e-21 75.7 0.6 0.00068 19.9 0.0 7.6 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 CEP09720.1 - 1.5e-20 73.4 0.1 0.0083 16.2 0.0 8.1 8 0 0 8 8 7 3 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CEP09720.1 - 2.9e-20 72.6 0.1 0.002 17.9 0.0 6.9 6 1 0 6 6 6 5 Sigma-54 interaction domain AAA_6 PF12774.7 CEP09720.1 - 1.1e-19 70.6 11.4 0.036 13.0 0.2 8.7 9 0 0 9 9 8 7 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 CEP09720.1 - 2.8e-18 66.2 0.0 0.0026 17.8 0.0 7.7 6 1 0 7 7 7 4 AAA domain ABC_tran PF00005.27 CEP09720.1 - 8.5e-17 62.0 0.3 0.0043 17.6 0.0 7.8 6 0 0 6 6 6 3 ABC transporter AAA_30 PF13604.6 CEP09720.1 - 2.4e-16 60.0 0.0 0.0046 16.7 0.0 8.0 7 1 0 7 7 7 3 AAA domain TsaE PF02367.17 CEP09720.1 - 1.6e-15 57.2 5.7 0.15 12.1 0.0 6.6 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CEP09720.1 - 6e-15 55.6 0.4 0.00036 20.7 0.0 6.0 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_33 PF13671.6 CEP09720.1 - 4.8e-13 49.5 3.4 1.4 9.1 0.0 7.2 6 1 0 6 6 6 2 AAA domain Zeta_toxin PF06414.12 CEP09720.1 - 7.8e-13 48.2 0.2 0.3 10.3 0.0 6.9 6 0 0 6 6 6 3 Zeta toxin AAA_28 PF13521.6 CEP09720.1 - 3.6e-12 46.8 3.3 0.59 10.4 0.0 7.0 6 0 0 6 6 6 1 AAA domain RsgA_GTPase PF03193.16 CEP09720.1 - 2.7e-11 43.7 2.2 1.1 9.2 0.0 6.5 6 0 0 6 6 6 2 RsgA GTPase AAA_25 PF13481.6 CEP09720.1 - 1.8e-10 40.7 1.3 0.29 10.7 0.0 5.9 5 0 0 5 5 5 2 AAA domain Rad17 PF03215.15 CEP09720.1 - 1.3e-09 38.3 0.8 0.24 11.3 0.0 5.8 5 0 0 5 5 5 2 Rad17 P-loop domain RNA_helicase PF00910.22 CEP09720.1 - 3.1e-09 37.2 7.1 0.61 10.5 0.0 8.0 8 0 0 8 8 7 2 RNA helicase T2SSE PF00437.20 CEP09720.1 - 5.7e-09 35.4 3.1 1.8 7.5 0.0 6.3 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_29 PF13555.6 CEP09720.1 - 6.5e-09 35.4 0.2 5.6 6.8 0.0 6.7 6 0 0 6 6 6 0 P-loop containing region of AAA domain RuvB_N PF05496.12 CEP09720.1 - 2.2e-08 34.0 0.9 0.91 9.3 0.0 7.2 9 0 0 9 9 7 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CEP09720.1 - 9.6e-08 31.5 1.8 1.1 8.3 0.0 5.6 6 0 0 6 6 5 3 Protein of unknown function (DUF815) NACHT PF05729.12 CEP09720.1 - 1.1e-07 32.0 11.2 0.19 11.6 0.0 6.1 7 0 0 7 7 5 2 NACHT domain Mg_chelatase PF01078.21 CEP09720.1 - 1.6e-07 31.0 5.7 0.17 11.2 0.0 8.1 8 1 0 8 8 8 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 CEP09720.1 - 6.4e-07 29.2 4.1 0.21 11.2 0.0 4.9 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CEP09720.1 - 2.3e-06 27.4 5.1 0.056 13.2 0.0 5.5 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CEP09720.1 - 3.7e-06 26.5 0.2 2.2 7.6 0.0 5.1 5 0 0 5 5 4 1 Bacterial TniB protein IstB_IS21 PF01695.17 CEP09720.1 - 3.9e-06 26.7 0.9 1.9 8.2 0.0 5.9 6 0 0 6 6 5 1 IstB-like ATP binding protein dNK PF01712.19 CEP09720.1 - 1.4e-05 25.1 4.5 9.2 6.1 0.0 6.6 6 0 0 6 6 6 0 Deoxynucleoside kinase cobW PF02492.19 CEP09720.1 - 1.6e-05 24.6 2.2 14 5.2 0.1 6.3 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CEP09720.1 - 2.3e-05 24.6 2.8 13 6.1 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CEP09720.1 - 0.00017 21.6 4.0 3 7.7 0.1 5.4 5 0 0 5 5 4 1 NTPase Viral_helicase1 PF01443.18 CEP09720.1 - 0.00017 21.4 0.2 1.4 8.6 0.0 4.7 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEP09720.1 - 0.00018 21.9 13.2 0.14 12.4 0.3 6.3 8 1 0 8 8 4 1 AAA domain MMR_HSR1 PF01926.23 CEP09720.1 - 0.00097 19.2 1.9 46 4.1 0.1 6.0 6 0 0 6 6 5 0 50S ribosome-binding GTPase SRPRB PF09439.10 CEP09720.1 - 0.0011 18.4 1.6 10 5.5 0.0 5.5 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit MCM PF00493.23 CEP09720.1 - 0.0012 18.0 0.0 13 4.7 0.0 4.3 4 0 0 4 4 4 0 MCM P-loop domain CPT PF07931.12 CEP09720.1 - 0.0016 18.3 5.9 21 4.9 0.0 7.4 8 1 0 8 8 7 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CEP09720.1 - 0.0018 17.7 0.1 8.3 5.7 0.0 4.5 4 0 0 4 4 4 0 KaiC VWA PF00092.28 CEP09720.1 - 0.0021 18.4 0.4 0.0068 16.7 0.4 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Thymidylate_kin PF02223.17 CEP09720.1 - 0.004 16.9 3.0 2.5 7.7 0.0 4.8 5 0 0 5 5 4 1 Thymidylate kinase Cytidylate_kin PF02224.18 CEP09720.1 - 0.0051 16.6 0.0 17 5.0 0.0 4.4 4 0 0 4 4 3 0 Cytidylate kinase ATP_bind_1 PF03029.17 CEP09720.1 - 0.006 16.4 10.9 1.5 8.6 0.1 5.8 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein PRK PF00485.18 CEP09720.1 - 0.012 15.4 0.2 39 3.9 0.0 4.5 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 CEP09720.1 - 0.086 12.6 0.0 6.8 6.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 CEP09720.1 - 0.093 12.8 1.5 26 4.9 0.0 4.7 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ploopntkinase3 PF18751.1 CEP09720.1 - 0.11 12.5 0.1 67 3.3 0.0 3.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 ResIII PF04851.15 CEP09720.1 - 1.7 8.6 16.9 0.98 9.4 0.2 5.2 6 0 0 6 6 3 0 Type III restriction enzyme, res subunit IPT PF01745.16 CEP09720.1 - 6.7 6.0 6.3 12 5.2 0.0 4.2 6 0 0 6 6 3 0 Isopentenyl transferase Arrestin_C PF02752.22 CEP09721.1 - 2.3e-07 31.3 1.0 2.3e-07 31.3 1.0 2.2 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain DDE_3 PF13358.6 CEP09722.1 - 3.8e-23 81.9 0.0 1.6e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_28 PF13518.6 CEP09722.1 - 0.00029 20.9 0.6 0.00055 20.0 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP09722.1 - 0.0012 18.6 0.1 0.0029 17.3 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP09722.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 CEP09722.1 - 0.039 14.6 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HA2 PF04408.23 CEP09724.1 - 8.4e-19 67.9 0.1 8.4e-19 67.9 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP09724.1 - 1.6e-12 47.7 0.0 4.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP09724.1 - 5.2e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP09724.1 - 5.3e-05 23.5 0.1 0.00029 21.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP09724.1 - 7e-05 23.2 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 CEP09724.1 - 0.00032 21.0 0.1 0.00071 19.9 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE PF00437.20 CEP09724.1 - 0.0043 16.1 0.1 0.016 14.3 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.15 CEP09724.1 - 0.006 16.6 0.4 0.045 13.8 0.2 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CEP09724.1 - 0.015 15.8 3.7 0.49 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CEP09724.1 - 0.018 14.6 0.1 7.5 6.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CEP09724.1 - 0.02 14.3 0.0 0.065 12.7 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 CEP09724.1 - 0.032 14.0 4.9 23 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CEP09724.1 - 0.085 12.2 0.0 0.26 10.6 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 CEP09724.1 - 0.11 12.6 0.2 2.6 8.1 0.2 2.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP09724.1 - 3.8 8.0 5.0 0.68 10.4 0.2 2.3 3 1 0 3 3 2 0 ABC transporter Aquarius_N PF16399.5 CEP09725.1 - 2.2e-290 965.4 13.0 2.8e-290 965.0 13.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 CEP09725.1 - 1.5e-28 100.3 0.0 5.5e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 CEP09725.1 - 2.2e-27 96.0 0.0 5e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP09725.1 - 1.6e-09 38.2 0.0 4.4e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP09725.1 - 8.4e-08 32.2 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain DEAD PF00270.29 CEP09725.1 - 4.3e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP09725.1 - 8e-05 22.7 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 CEP09725.1 - 0.00046 20.0 0.1 0.00095 19.0 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CEP09725.1 - 0.0012 18.4 0.1 0.0074 15.9 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 CEP09725.1 - 0.0014 17.9 0.4 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEP09725.1 - 0.0038 16.7 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 CEP09725.1 - 0.0055 17.1 0.0 0.024 15.0 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEP09725.1 - 0.0079 16.5 0.1 0.086 13.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CEP09725.1 - 0.023 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEP09725.1 - 0.1 13.0 0.3 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DnaB_C PF03796.15 CEP09725.1 - 0.11 11.8 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TFIID-18kDa PF02269.16 CEP09726.1 - 3.5e-28 97.5 0.2 4.5e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Pex2_Pex12 PF04757.14 CEP09727.1 - 4.1e-36 124.7 5.1 5.6e-36 124.2 5.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 CEP09727.1 - 0.0007 19.4 6.2 0.0014 18.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP09727.1 - 0.0055 16.8 3.8 0.0055 16.8 3.8 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEP09727.1 - 0.0085 15.9 5.7 0.026 14.4 2.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP09727.1 - 0.017 15.1 6.8 0.042 13.8 6.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP09727.1 - 0.073 13.1 6.5 0.16 12.0 6.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger KRTDAP PF15200.6 CEP09727.1 - 0.083 12.7 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated zf-rbx1 PF12678.7 CEP09727.1 - 0.62 10.4 5.9 1.1 9.6 5.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEP09727.1 - 0.93 9.9 8.4 3.8 7.9 8.4 2.0 1 1 0 1 1 1 0 Ring finger domain EHN PF06441.12 CEP09729.1 - 7.9e-29 100.2 3.4 1.6e-28 99.2 3.4 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CEP09729.1 - 6.8e-12 45.6 0.0 2.1e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP09729.1 - 4.7e-09 37.2 0.0 6.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_1 PF00175.21 CEP09730.1 - 5e-27 94.7 0.0 5e-27 94.7 0.0 4.2 4 1 1 5 5 5 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEP09730.1 - 2.3e-14 53.5 0.0 7.7e-14 51.8 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEP09730.1 - 0.0045 17.1 0.0 0.0045 17.1 0.0 5.0 3 2 1 4 4 4 2 Ferric reductase NAD binding domain HAP1_N PF04849.13 CEP09731.1 - 8.5e-06 25.2 0.0 8.5e-06 25.2 0.0 2.5 2 1 1 3 3 3 1 HAP1 N-terminal conserved region Cep57_CLD_2 PF14197.6 CEP09731.1 - 0.0082 16.2 0.7 0.0082 16.2 0.7 5.0 4 2 1 5 5 5 1 Centrosome localisation domain of PPC89 NPV_P10 PF05531.12 CEP09731.1 - 0.24 11.9 12.3 0.68 10.4 0.1 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CEP09731.1 - 1.4 8.2 16.0 3.2 7.0 16.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 CEP09731.1 - 4.9 6.7 27.1 0.1 12.2 9.1 3.2 1 1 2 3 3 3 0 PspA/IM30 family DUF3450 PF11932.8 CEP09731.1 - 8.9 5.5 22.0 1.5 8.1 3.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 CEP09731.1 - 9.8 6.2 28.1 3.8 7.6 10.4 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus zf-CCHC_4 PF14392.6 CEP09732.1 - 0.11 12.3 0.7 0.21 11.3 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Spt20 PF12090.8 CEP09732.1 - 1.6 8.3 11.3 0.22 11.1 6.9 1.8 2 0 0 2 2 2 0 Spt20 family EAV_GS PF01309.18 CEP09734.1 - 0.062 12.9 0.2 4.1 7.0 0.0 2.1 1 1 1 2 2 2 0 Equine arteritis virus small envelope glycoprotein CotH PF08757.11 CEP09735.1 - 6.5e-38 131.1 1.5 1e-37 130.4 1.5 1.2 1 0 0 1 1 1 1 CotH kinase protein Fungal_trans PF04082.18 CEP09736.1 - 4.7e-39 134.0 0.1 1e-38 132.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP09736.1 - 4.1e-11 42.8 8.9 4.1e-11 42.8 8.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.18 CEP09737.1 - 2.1e-11 43.9 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP09737.1 - 0.002 18.0 0.1 0.0027 17.6 0.1 1.2 1 0 0 1 1 1 1 Barwin family DUF3039 PF11238.8 CEP09737.1 - 0.2 11.4 0.4 0.39 10.5 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3039) Cyclin_C_2 PF16899.5 CEP09738.1 - 4.9e-05 23.6 0.1 0.00017 21.9 0.1 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain Methyltransf_7 PF03492.15 CEP09739.1 - 0.01 15.0 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Metallophos PF00149.28 CEP09740.1 - 2.3e-34 119.7 0.3 3.8e-34 119.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CEP09740.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PPP5 TPR repeat region Acyltransferase PF01553.21 CEP09741.1 - 5.1e-08 32.6 0.0 2.9e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase SNF2_N PF00176.23 CEP09742.1 - 8.7e-77 258.2 0.0 1.6e-76 257.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP09742.1 - 2e-19 70.0 0.0 4e-18 65.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 CEP09742.1 - 1.2e-15 57.2 0.0 2.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 CEP09742.1 - 5e-08 33.1 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEP09742.1 - 6.4e-08 32.6 0.1 2.5e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA_4 PF14555.6 CEP09742.1 - 6.1e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 CEP09742.1 - 7.7e-05 22.3 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain zf-RING_UBOX PF13445.6 CEP09742.1 - 0.00016 21.6 4.6 0.00016 21.6 4.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP09742.1 - 0.00062 19.6 6.2 0.0014 18.4 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP09742.1 - 0.00074 19.3 4.8 0.0029 17.4 4.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP09742.1 - 0.00075 19.8 8.7 0.0052 17.1 8.7 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEP09742.1 - 0.0019 18.1 7.2 0.0047 16.9 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP09742.1 - 0.0033 17.2 4.3 0.0033 17.2 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP09742.1 - 9 6.5 10.1 4 7.7 6.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Asp-B-Hydro_N PF05279.11 CEP09745.1 - 4.2 7.4 36.2 1.9 8.5 30.3 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PSP1 PF04468.12 CEP09746.1 - 8.5e-33 112.5 3.8 4.4e-32 110.2 4.6 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Pox_A3L PF05288.11 CEP09746.1 - 0.0066 16.4 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Poxvirus A3L Protein DRMBL PF07522.14 CEP09747.1 - 0.0013 18.9 0.1 0.0046 17.1 0.1 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase YmgD PF16456.5 CEP09747.1 - 0.15 12.1 0.7 0.4 10.8 0.2 1.9 2 0 0 2 2 2 0 YmgD protein Abhydrolase_1 PF00561.20 CEP09748.1 - 2.1e-14 53.8 0.0 8.2e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP09748.1 - 8.1e-06 25.3 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methylase_S PF01420.19 CEP09748.1 - 0.066 13.4 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Abp2 PF09441.10 CEP09749.1 - 2.1e-20 73.5 0.1 5.4e-20 72.2 0.1 1.7 1 0 0 1 1 1 1 ARS binding protein 2 KH_1 PF00013.29 CEP09750.1 - 2.9e-23 81.5 0.0 4.1e-06 26.5 0.0 6.8 7 0 0 7 7 7 6 KH domain DUF4974 PF16344.5 CEP09750.1 - 0.0011 18.9 0.5 1.4 9.0 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4974) FlaG PF03646.15 CEP09750.1 - 0.43 10.8 1.7 11 6.2 0.2 3.2 3 0 0 3 3 3 0 FlaG protein Dioxygenase_N PF04444.14 CEP09751.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Catechol dioxygenase N terminus MOZ_SAS PF01853.18 CEP09752.1 - 1.5e-46 158.3 0.5 1.8e-46 158.0 0.1 1.3 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_7 PF13508.7 CEP09752.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP09752.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-RVT PF13966.6 CEP09753.1 - 1e-05 26.2 0.5 2.1e-05 25.2 0.5 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WD40 PF00400.32 CEP09754.1 - 7.7e-40 134.2 19.4 1.3e-06 29.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP09754.1 - 6.2e-11 42.4 0.1 0.024 14.9 0.1 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP09754.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 CEP09754.1 - 0.093 11.2 0.0 0.24 9.9 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ribonuc_L-PSP PF01042.21 CEP09755.1 - 4.7e-47 159.0 0.7 5.2e-47 158.8 0.7 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Flot PF15975.5 CEP09755.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Flotillin Sel1 PF08238.12 CEP09756.1 - 1.2e-30 105.2 22.3 1.3e-08 35.2 0.9 7.2 7 1 0 7 7 7 5 Sel1 repeat TPR_7 PF13176.6 CEP09756.1 - 0.022 14.8 1.6 11 6.3 0.0 3.9 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP09756.1 - 0.05 13.9 2.3 5 7.5 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP09756.1 - 0.053 13.6 9.1 1.6 9.0 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEP09756.1 - 0.46 11.5 3.4 6.4 7.9 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP09756.1 - 1.6 8.7 8.6 12 5.9 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP09756.1 - 1.7 9.0 9.0 5.4 7.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 CEP09757.1 - 1.3e-16 60.7 2.5 4.1e-15 55.9 0.1 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP09757.1 - 4.5e-08 33.2 1.6 6.3e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CEP09757.1 - 7.2e-07 28.9 0.1 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 CEP09757.1 - 0.00014 21.3 3.8 0.00026 20.4 0.1 2.4 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 CEP09757.1 - 0.0064 16.6 8.8 0.051 13.6 0.1 3.7 3 0 0 3 3 3 1 Dynamin family DUF4193 PF13834.6 CEP09757.1 - 2.2 8.8 8.1 4.1 8.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) PMSI1 PF15322.6 CEP09757.1 - 6.2 6.2 8.1 2.5 7.5 2.1 2.2 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative Aminotran_1_2 PF00155.21 CEP09758.1 - 6.4e-26 91.4 0.0 7.1e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEP09758.1 - 4.5e-09 35.6 0.0 6.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase 5_nucleotid PF05761.14 CEP09759.1 - 1.8e-96 323.8 9.0 9.1e-71 239.1 0.3 4.2 1 1 2 3 3 3 3 5' nucleotidase family Drc1-Sld2 PF11719.8 CEP09762.1 - 3.8e-11 43.2 9.0 3.8e-11 43.2 9.0 3.1 2 1 1 3 3 3 2 DNA replication and checkpoint protein DUF3245 PF11595.8 CEP09762.1 - 1.9 8.9 13.4 0.13 12.7 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Nucleoside_tran PF01733.18 CEP09764.1 - 4.2e-54 184.0 18.3 1.1e-53 182.7 16.5 2.3 1 1 1 2 2 2 2 Nucleoside transporter MnhB PF04039.13 CEP09764.1 - 0.081 13.2 11.7 0.41 11.0 0.3 3.5 3 2 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter UCR_TM PF02921.14 CEP09764.1 - 0.12 12.9 0.1 5 7.7 0.0 3.0 2 1 1 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region AA_permease_2 PF13520.6 CEP09765.1 - 4.9e-55 187.1 56.9 6e-55 186.8 56.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP09765.1 - 1.3e-38 132.9 49.8 1.6e-38 132.5 49.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 CEP09765.1 - 8.6e-06 25.7 6.1 8.6e-06 25.7 6.1 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease PrgI PF12666.7 CEP09765.1 - 0.036 14.8 2.4 0.036 14.8 2.4 4.9 5 2 0 5 5 5 0 PrgI family protein NADHdh_A3 PF14987.6 CEP09765.1 - 0.64 10.3 2.3 7 7.0 0.6 2.9 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Tantalus PF15386.6 CEP09766.1 - 0.015 15.4 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like DUF3552 PF12072.8 CEP09766.1 - 0.019 14.4 0.4 0.024 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2730 PF10805.8 CEP09766.1 - 0.05 13.7 0.1 0.083 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Peptidase_M28 PF04389.17 CEP09767.1 - 2.6e-37 128.5 0.0 4.5e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 zf-C2H2_4 PF13894.6 CEP09768.1 - 0.0025 18.5 1.8 0.0069 17.1 1.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP09768.1 - 0.004 17.5 2.5 0.0078 16.6 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 CEP09768.1 - 0.0075 16.6 0.7 0.019 15.3 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP09768.1 - 0.017 15.4 0.2 0.037 14.3 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CEP09768.1 - 0.028 14.2 5.3 0.028 14.2 5.3 1.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CEP09768.1 - 0.054 13.5 1.1 0.096 12.7 1.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger CHIP_TPR_N PF18391.1 CEP09768.1 - 0.16 12.8 1.7 0.25 12.1 1.7 1.4 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain Rap_GAP PF02145.15 CEP09769.1 - 9.6e-43 145.9 0.0 2.5e-42 144.5 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP HTH_Tnp_Tc3_1 PF11427.8 CEP09769.1 - 0.025 14.4 0.1 0.096 12.6 0.1 2.0 1 0 0 1 1 1 0 Tc3 transposase DUF3220 PF11516.8 CEP09769.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) rve PF00665.26 CEP09771.1 - 9.4e-06 25.8 0.0 2.3e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain KHA PF11834.8 CEP09773.1 - 0.048 13.7 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Retrotrans_gag PF03732.17 CEP09774.1 - 0.021 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein zf-RVT PF13966.6 CEP09776.1 - 2.3e-05 25.0 0.3 4e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.18 CEP09777.1 - 6.2e-07 29.6 0.0 1.8e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 Transposase HlyIII PF03006.20 CEP09778.1 - 1.4e-57 195.0 22.0 1.7e-57 194.7 22.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ras PF00071.22 CEP09779.1 - 7.1e-30 103.7 0.2 8.5e-30 103.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP09779.1 - 1.5e-22 80.1 0.1 3.2e-22 79.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP09779.1 - 4.2e-06 26.3 0.0 5.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 CEP09779.1 - 1.2e-05 24.4 0.1 0.037 12.9 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 CEP09779.1 - 0.0033 16.8 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP09779.1 - 0.013 15.0 0.1 0.26 10.8 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TniB PF05621.11 CEP09779.1 - 0.014 14.8 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DPBB_1 PF03330.18 CEP09780.1 - 1.4e-12 47.7 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP09780.1 - 0.092 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Barwin family Pkinase PF00069.25 CEP09782.1 - 1.7e-64 217.7 0.0 2.5e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09782.1 - 4e-50 170.5 0.0 7e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 CEP09782.1 - 3.1e-05 24.0 0.1 9.4e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CEP09782.1 - 3.7e-05 23.2 0.0 0.044 13.1 0.0 2.6 2 0 0 2 2 2 2 Kinase-like SAM_1 PF00536.30 CEP09782.1 - 0.00016 22.0 0.1 0.00037 20.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 CEP09782.1 - 0.0004 20.7 0.0 0.00095 19.5 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Pkinase_fungal PF17667.1 CEP09782.1 - 0.0012 17.7 0.1 0.0042 15.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEP09782.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.17 CEP09783.1 - 8.7e-45 152.8 0.1 9.8e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family NDC10_II PF16787.5 CEP09784.1 - 9.8e-24 84.0 0.4 7e-12 45.0 0.0 2.5 2 1 1 3 3 3 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 LemA PF04011.12 CEP09784.1 - 0.064 13.1 0.2 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 LemA family TSLP PF15216.6 CEP09784.1 - 0.29 11.4 4.7 0.29 11.4 2.9 1.8 2 0 0 2 2 2 0 Thymic stromal lymphopoietin E1-E2_ATPase PF00122.20 CEP09786.1 - 8.5e-44 149.2 6.3 8.5e-44 149.2 6.3 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CEP09786.1 - 8.5e-23 81.7 0.8 1.4e-22 81.1 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP09786.1 - 2.3e-09 36.8 0.0 7.4e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP09786.1 - 0.0026 17.5 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP09786.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Phage_holin_3_6 PF07332.11 CEP09786.1 - 0.3 11.1 0.0 0.3 11.1 0.0 3.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_membrane PF00664.23 CEP09787.1 - 1e-59 202.5 25.8 1.7e-36 126.3 7.2 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP09787.1 - 3.9e-48 163.5 0.0 5.3e-28 98.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP09787.1 - 4.2e-07 29.6 10.4 0.0036 16.8 2.8 4.4 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEP09787.1 - 1.2e-05 25.0 0.5 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 CEP09787.1 - 3.7e-05 22.9 0.1 0.041 12.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 CEP09787.1 - 9.2e-05 23.0 5.3 0.022 15.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CEP09787.1 - 0.00013 22.3 0.3 0.9 9.8 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CEP09787.1 - 0.00018 21.3 0.6 0.0096 15.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 CEP09787.1 - 0.00024 20.6 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 CEP09787.1 - 0.00049 20.5 0.7 0.76 10.1 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CEP09787.1 - 0.00062 19.7 0.1 1.9 8.2 0.0 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CEP09787.1 - 0.001 19.1 0.2 1.8 8.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP09787.1 - 0.0027 17.6 0.2 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 CEP09787.1 - 0.0046 17.1 1.7 0.61 10.1 0.2 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 CEP09787.1 - 0.0056 16.8 1.9 0.064 13.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 CEP09787.1 - 0.0076 15.8 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP09787.1 - 0.011 15.2 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEP09787.1 - 0.024 14.4 0.2 13 5.5 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_15 PF13175.6 CEP09787.1 - 0.025 14.3 5.0 1.7 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain AAA_33 PF13671.6 CEP09787.1 - 0.031 14.4 0.6 0.84 9.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP09787.1 - 0.034 14.5 0.0 6.2 7.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 CEP09787.1 - 0.073 12.8 0.8 12 5.5 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CEP09787.1 - 0.076 13.6 0.3 8.7 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CEP09787.1 - 0.1 11.9 0.0 6.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 CEP09787.1 - 0.1 11.9 0.4 7.4 5.8 0.0 2.8 3 0 0 3 3 3 0 KaiC TrwB_AAD_bind PF10412.9 CEP09787.1 - 0.13 11.2 0.3 3.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CEP09787.1 - 0.36 10.7 1.3 18 5.2 0.0 3.0 3 0 0 3 3 3 0 NACHT domain LapA_dom PF06305.11 CEP09787.1 - 0.51 10.2 7.8 1.8 8.4 0.6 3.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ninjurin PF04923.12 CEP09787.1 - 2.1 8.3 4.5 1.4 8.9 0.1 3.0 3 1 1 4 4 4 0 Ninjurin HTH_Tnp_Tc3_2 PF01498.18 CEP09788.1 - 3.3e-07 30.5 0.0 4.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Transposase Fumerase PF05681.14 CEP09788.1 - 0.009 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) HTH_28 PF13518.6 CEP09789.1 - 0.008 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP09789.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.7 CEP09789.1 - 0.038 13.9 0.0 0.29 11.1 0.0 1.9 1 1 1 2 2 2 0 MarR family HTH_23 PF13384.6 CEP09789.1 - 0.045 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_5 PF01022.20 CEP09789.1 - 0.15 12.0 0.2 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Mad3_BUB1_I PF08311.12 CEP09790.1 - 9.1e-41 138.7 1.2 2e-40 137.6 1.2 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 CEP09790.1 - 2.2e-08 34.3 0.2 4.6e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Vps35 PF03635.17 CEP09791.1 - 2e-260 866.4 20.5 2.3e-260 866.2 20.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TRAP_alpha PF03896.16 CEP09791.1 - 0.026 13.8 2.5 0.044 13.0 2.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 CEP09791.1 - 0.039 13.3 9.4 0.066 12.6 9.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 CEP09791.1 - 0.071 11.9 5.0 0.12 11.1 5.0 1.3 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CEP09791.1 - 0.073 12.8 2.7 0.16 11.7 2.7 1.5 1 0 0 1 1 1 0 Connexin AIF_C PF14721.6 CEP09791.1 - 0.11 12.9 4.0 0.25 11.7 4.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.15 CEP09791.1 - 0.11 11.4 2.0 0.18 10.7 2.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF913 PF06025.12 CEP09791.1 - 0.18 10.7 3.6 0.34 9.8 3.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 CEP09791.1 - 0.61 10.2 4.4 1.2 9.3 4.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.5 CEP09791.1 - 0.72 9.6 5.0 2.5 7.8 5.0 1.9 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH EF-hand_1 PF00036.32 CEP09792.1 - 4.6e-42 138.4 11.9 1.5e-10 39.9 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP09792.1 - 2.1e-35 121.0 3.3 2.4e-19 69.6 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEP09792.1 - 9.2e-33 111.9 11.0 6.8e-15 54.7 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CEP09792.1 - 3.5e-31 104.4 8.1 1.6e-09 36.9 0.0 4.7 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEP09792.1 - 4.9e-26 89.0 10.5 1.7e-06 27.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEP09792.1 - 1e-14 54.6 0.1 1.3e-07 31.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP09792.1 - 2.4e-10 40.7 0.4 0.00014 22.2 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP09792.1 - 2.5e-10 40.2 1.1 0.00016 21.6 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CEP09792.1 - 6.7e-06 26.1 1.5 7.8e-05 22.7 0.3 2.5 2 2 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 CEP09792.1 - 4e-05 24.4 0.1 0.0009 20.1 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CEP09792.1 - 7e-05 22.9 5.3 0.87 9.8 5.4 3.1 1 1 1 2 2 2 1 Dockerin type I domain Caleosin PF05042.13 CEP09792.1 - 0.00023 21.1 1.1 1.1 9.2 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 CEP09792.1 - 0.00027 21.6 0.6 2.8 8.8 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) TerB PF05099.13 CEP09792.1 - 0.00031 20.7 1.7 0.14 12.1 0.1 2.5 1 1 2 3 3 3 2 Tellurite resistance protein TerB DUF2267 PF10025.9 CEP09792.1 - 0.0013 18.9 0.0 0.0075 16.5 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) DUF5580 PF17743.1 CEP09792.1 - 0.0015 17.2 0.0 0.0016 17.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 CEP09792.1 - 0.0029 17.9 2.9 0.81 10.0 0.2 3.0 2 1 1 3 3 3 1 RNA polymerase Rpb4 UPF0154 PF03672.13 CEP09792.1 - 0.0049 16.9 0.6 0.31 11.1 0.0 3.1 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0154) SurA_N_2 PF13623.6 CEP09792.1 - 0.007 16.2 1.8 0.67 9.8 0.3 2.3 1 1 1 2 2 2 2 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 CEP09792.1 - 0.011 15.4 0.6 0.034 13.8 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF4497 PF14924.6 CEP09792.1 - 0.011 16.1 0.0 0.1 13.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) RPN13_C PF16550.5 CEP09792.1 - 0.026 14.7 0.0 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 UCH-binding domain DUF853 PF05872.12 CEP09792.1 - 0.027 13.1 0.1 0.22 10.0 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Spore_III_AB PF09548.10 CEP09792.1 - 0.038 14.1 0.6 0.063 13.4 0.6 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) p25-alpha PF05517.12 CEP09792.1 - 0.05 13.8 0.4 7.6 6.7 0.2 2.3 1 1 1 2 2 2 0 p25-alpha DUF1811 PF08838.10 CEP09792.1 - 0.071 13.4 0.4 16 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) CMD PF02627.20 CEP09792.1 - 0.11 12.5 0.5 2.2 8.4 0.0 2.9 3 1 0 3 3 3 0 Carboxymuconolactone decarboxylase family DUF1456 PF07308.13 CEP09792.1 - 0.15 12.4 1.0 5.9 7.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) AidB_N PF18158.1 CEP09794.1 - 7.1e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 CEP09794.1 - 2e-22 80.0 0.4 3.7e-22 79.1 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEP09794.1 - 6.2e-14 52.0 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEP09794.1 - 4.2e-08 33.5 0.0 8.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TYA PF01021.19 CEP09795.1 - 0.02 15.2 0.8 0.024 15.0 0.8 1.2 1 0 0 1 1 1 0 TYA transposon protein LpoB PF13036.6 CEP09795.1 - 0.098 12.6 0.2 0.12 12.3 0.2 1.0 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB SRP9-21 PF05486.12 CEP09796.1 - 1.7e-09 37.9 6.4 1.2e-08 35.2 3.2 2.4 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) SET PF00856.28 CEP09797.1 - 1.7e-23 83.9 0.4 3.2e-23 83.0 0.1 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 CEP09797.1 - 2.3e-15 57.4 0.6 2.3e-15 57.4 0.6 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding RNA_pol_3_Rpc31 PF11705.8 CEP09797.1 - 0.019 15.3 4.8 0.035 14.3 4.8 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 CEP09797.1 - 0.021 14.5 3.0 0.051 13.2 3.0 1.6 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 CEP09797.1 - 0.04 14.1 1.9 0.079 13.1 0.9 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal JCAD PF15351.6 CEP09797.1 - 0.059 11.1 2.9 0.078 10.8 2.9 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease NOA36 PF06524.12 CEP09797.1 - 0.17 11.2 4.8 0.31 10.3 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CEP09797.1 - 4.9 7.6 9.2 9.5 6.7 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 CEP09797.1 - 6.3 6.5 10.2 8.1 6.2 6.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PseudoU_synth_1 PF01416.20 CEP09798.1 - 3.8e-29 101.3 0.0 4.1e-26 91.5 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Retrotran_gag_2 PF14223.6 CEP09799.1 - 0.0076 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PHD PF00628.29 CEP09800.1 - 8.8e-10 38.3 12.7 8.8e-10 38.3 12.7 1.9 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 CEP09800.1 - 1.6e-05 25.4 0.2 1.6e-05 25.4 0.2 3.3 2 2 0 2 2 2 1 SET domain PHD_2 PF13831.6 CEP09800.1 - 0.013 15.1 5.6 0.025 14.1 5.6 1.5 1 0 0 1 1 1 0 PHD-finger PolC_DP2 PF03833.13 CEP09800.1 - 0.32 8.8 5.8 0.6 7.9 5.8 1.4 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 ArgJ PF01960.18 CEP09801.1 - 3.8e-150 499.8 2.3 4.3e-150 499.6 2.3 1.0 1 0 0 1 1 1 1 ArgJ family FYRN PF05964.14 CEP09801.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus DNA_pol_B PF00136.21 CEP09802.1 - 8.8e-151 502.7 2.1 8.8e-151 502.7 2.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEP09802.1 - 1.5e-85 287.3 0.1 6.6e-84 281.9 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CEP09802.1 - 1.1e-17 64.2 7.3 2.7e-17 63.0 7.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CEP09802.1 - 1.4e-05 24.1 1.3 0.0012 17.7 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CEP09802.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CEP09802.1 - 0.021 14.8 0.1 0.1 12.6 0.1 2.2 1 1 0 1 1 1 0 RNase_H superfamily C1_1 PF00130.22 CEP09802.1 - 0.039 13.9 5.0 0.13 12.1 5.0 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NICE-3 PF07406.11 CEP09802.1 - 0.15 12.0 0.4 0.46 10.4 0.3 1.8 2 0 0 2 2 2 0 NICE-3 protein zf-ACC PF17848.1 CEP09802.1 - 1.9 8.6 5.3 1.2 9.3 0.8 2.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 CEP09802.1 - 4.9 7.3 8.2 12 6.0 8.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_L1 PF00687.21 CEP09803.1 - 1.4e-35 122.9 1.1 1.6e-35 122.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L5_C PF00673.21 CEP09804.1 - 1.2e-27 96.0 0.0 1.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEP09804.1 - 3e-13 49.9 0.0 5.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 LCAT PF02450.15 CEP09805.1 - 6.1e-68 229.8 0.0 6.2e-67 226.4 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 CEP09805.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Kinesin PF00225.23 CEP09806.1 - 2.8e-82 276.3 2.5 4.2e-80 269.2 0.1 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP09806.1 - 7.5e-09 35.7 0.2 5e-07 29.8 0.0 3.4 3 1 0 3 3 3 1 Microtubule binding DUF641 PF04859.12 CEP09806.1 - 0.022 15.1 1.8 0.022 15.1 1.8 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF3533 PF12051.8 CEP09806.1 - 0.13 11.2 1.7 0.34 9.8 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) OmpH PF03938.14 CEP09806.1 - 4.1 7.7 11.4 0.27 11.6 0.5 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Thaumatin PF00314.17 CEP09807.1 - 4.4e-51 173.6 14.7 5.5e-51 173.2 14.7 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CEP09807.1 - 0.19 11.0 2.1 2.7 7.2 0.0 2.2 1 1 0 2 2 2 0 Beta-1,3-glucanase Fungal_trans PF04082.18 CEP09808.1 - 1.3e-11 44.1 0.3 1.3e-11 44.1 0.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP09808.1 - 1.8e-05 24.8 9.0 4e-05 23.6 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tti2 PF10521.9 CEP09808.1 - 0.11 12.1 0.0 0.11 12.1 0.0 3.3 4 0 0 4 4 4 0 Tti2 family Enoyl_reductase PF12241.8 CEP09809.1 - 0.033 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region LRR_8 PF13855.6 CEP09810.1 - 4.2e-23 80.9 34.1 7.2e-12 44.9 5.6 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEP09810.1 - 8.4e-12 45.1 14.3 4.9e-07 30.0 0.9 3.4 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP09810.1 - 3.8e-07 29.7 8.9 0.049 14.2 0.3 5.3 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.6 CEP09810.1 - 0.00011 22.0 16.2 0.17 12.0 1.2 4.7 4 0 0 4 4 4 3 Leucine Rich repeat Eisosome1 PF12757.7 CEP09810.1 - 0.0036 17.6 0.1 0.01 16.1 0.1 1.7 1 0 0 1 1 1 1 Eisosome protein 1 LRR_9 PF14580.6 CEP09810.1 - 0.02 14.4 1.8 0.044 13.3 1.8 1.6 1 0 0 1 1 1 0 Leucine-rich repeat DUF1672 PF07901.11 CEP09810.1 - 0.043 13.2 0.4 0.097 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) LRR_3 PF07725.12 CEP09810.1 - 8.4 6.4 6.4 8.5 6.4 1.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat MFS_1 PF07690.16 CEP09811.1 - 3.5e-46 157.8 32.2 1.8e-45 155.4 23.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP09811.1 - 0.00012 21.1 35.7 0.002 17.0 35.6 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter Transgly_assoc PF04226.13 CEP09811.1 - 0.24 11.7 5.4 1.8 8.9 3.2 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein Glyco_hydro_16 PF00722.21 CEP09812.1 - 1.4e-23 83.3 0.1 2.5e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Invasin_D3 PF09134.10 CEP09812.1 - 0.09 13.1 0.1 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 Invasin, domain 3 Band_7 PF01145.25 CEP09813.1 - 1.1e-24 87.4 2.0 2e-24 86.6 2.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 CEP09813.1 - 0.073 13.2 0.6 0.35 11.0 0.6 2.1 1 1 0 1 1 1 0 LD-carboxypeptidase N-terminal domain PIG-X PF08320.12 CEP09814.1 - 3.4e-35 121.9 0.2 4.4e-35 121.5 0.2 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 VHS PF00790.19 CEP09815.1 - 2.4e-39 134.4 2.6 1.7e-38 131.7 0.0 2.8 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 CEP09815.1 - 9.2e-09 35.3 7.2 1.9e-08 34.3 7.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CEP09815.1 - 4.5e-06 26.2 8.9 0.007 16.2 0.5 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif Hrs_helical PF12210.8 CEP09815.1 - 4.6e-06 27.1 1.2 4.6e-06 27.1 1.2 2.6 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.14 CEP09815.1 - 2.3e-05 24.6 2.6 4e-05 23.8 0.7 2.4 2 0 0 2 2 2 1 GAT domain MurB_C PF02873.16 CEP09815.1 - 0.058 13.5 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Syntaxin_2 PF14523.6 CEP09815.1 - 0.33 11.3 9.3 0.082 13.3 2.4 2.8 2 0 0 2 2 2 0 Syntaxin-like protein HypA PF01155.19 CEP09815.1 - 2.8 8.0 7.3 36 4.4 4.5 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Roughex PF06020.11 CEP09816.1 - 0.44 9.6 3.9 0.6 9.2 3.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Astro_capsid_p PF12226.8 CEP09816.1 - 1.9 7.6 10.2 2.8 7.0 10.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 CEP09816.1 - 2.3 6.3 8.6 3.3 5.8 8.6 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 CEP09817.1 - 4e-08 33.0 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAMP PF00672.25 CEP09819.1 - 5.9e-51 170.7 16.8 4.5e-09 36.6 0.1 6.7 6 0 0 6 6 6 6 HAMP domain ImcF-related_N PF14331.6 CEP09819.1 - 3.4e-06 26.6 0.2 2.4 7.4 0.0 4.6 2 2 2 5 5 5 2 ImcF-related N-terminal domain HTH_6 PF01418.17 CEP09819.1 - 4.9e-06 26.4 1.3 19 5.3 0.0 6.2 6 0 0 6 6 5 0 Helix-turn-helix domain, rpiR family PseudoU_synth_1 PF01416.20 CEP09819.1 - 2.1e-05 24.9 3.5 34 5.0 0.0 6.0 4 2 0 5 5 5 0 tRNA pseudouridine synthase DUF1843 PF08898.10 CEP09819.1 - 0.00084 19.8 6.8 20 5.8 0.0 6.0 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) Zw10 PF06248.13 CEP09819.1 - 0.0009 17.9 7.1 3 6.3 0.8 4.3 1 1 4 5 5 5 3 Centromere/kinetochore Zw10 Vac_Fusion PF02346.16 CEP09819.1 - 0.01 15.4 4.8 54 3.5 0.0 7.0 9 0 0 9 9 9 0 Chordopoxvirus multifunctional envelope protein A27 DUF948 PF06103.11 CEP09819.1 - 0.023 14.9 45.8 2.2 8.6 3.2 8.7 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) SpoIIID PF12116.8 CEP09819.1 - 0.027 14.6 4.9 71 3.6 0.0 5.5 6 0 0 6 6 5 0 Stage III sporulation protein D DUF4731 PF15875.5 CEP09819.1 - 0.035 14.3 9.6 3.6 7.8 0.1 5.8 5 3 0 5 5 5 0 Domain of unknown function (DUF4731) GrpE PF01025.19 CEP09819.1 - 0.036 13.7 0.0 3.5 7.3 0.0 3.5 1 1 3 4 4 4 0 GrpE TMEM126 PF07114.11 CEP09819.1 - 0.069 12.5 1.3 84 2.5 0.0 4.0 4 0 0 4 4 4 0 Transmembrane protein 126 GLE1 PF07817.13 CEP09819.1 - 0.22 10.7 2.5 4.3 6.5 0.0 3.6 1 1 4 5 5 5 0 GLE1-like protein Vps52 PF04129.12 CEP09819.1 - 0.3 9.8 0.8 48 2.5 0.0 3.9 5 0 0 5 5 5 0 Vps52 / Sac2 family Fib_alpha PF08702.10 CEP09819.1 - 0.84 9.8 12.1 10 6.3 0.1 5.3 6 1 0 6 6 6 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 CEP09819.1 - 1.5 8.9 11.7 34 4.4 0.1 5.2 5 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1725 PF08333.11 CEP09819.1 - 2.1 8.1 11.4 9.4 6.0 0.3 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1725) rve PF00665.26 CEP09820.1 - 9.7e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 CEP09820.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain CssAB PF16831.5 CEP09821.1 - 0.53 10.7 10.4 0.64 10.4 5.2 2.8 1 1 2 3 3 3 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 PA-IIL PF07472.11 CEP09821.1 - 8 6.8 13.8 0.077 13.3 3.5 2.7 1 1 2 3 3 3 0 Fucose-binding lectin II (PA-IIL) PDZ_1 PF12812.7 CEP09822.1 - 6.3e-42 141.5 0.0 1.2e-29 102.2 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.6 CEP09822.1 - 6e-14 52.1 0.0 6e-06 26.5 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.6 CEP09822.1 - 6.1e-14 53.2 1.2 6.4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 CEP09822.1 - 3.5e-12 46.0 0.0 0.00043 20.1 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 CEP09822.1 - 4.8e-10 39.7 0.0 5.5e-05 23.4 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 CEP09822.1 - 0.017 15.1 0.1 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 Tricorn protease PDZ domain DUF31 PF01732.16 CEP09822.1 - 0.24 10.9 0.2 0.34 10.4 0.2 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Hist_deacetyl PF00850.19 CEP09823.1 - 0.01 15.3 1.1 0.014 14.9 0.1 1.7 2 0 0 2 2 2 0 Histone deacetylase domain HTH_23 PF13384.6 CEP09825.1 - 0.00022 20.9 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP09825.1 - 0.0022 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP09825.1 - 0.0098 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP09825.1 - 0.01 16.1 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Transposase LON_substr_bdg PF02190.16 CEP09825.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain TrmB PF01978.19 CEP09825.1 - 0.022 14.7 0.0 0.086 12.7 0.0 1.8 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 CEP09825.1 - 0.03 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_37 PF13744.6 CEP09825.1 - 0.031 14.2 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_1 PF00126.27 CEP09825.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 CEP09825.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 CEP09825.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 CEP09825.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 MarR family DDE_3 PF13358.6 CEP09826.1 - 5.1e-15 55.5 0.0 7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF19 PF01579.18 CEP09826.1 - 0.021 14.6 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DUF4572 PF15139.6 CEP09826.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) RNB PF00773.19 CEP09827.1 - 1.5e-83 280.8 0.0 7.7e-83 278.5 0.0 2.2 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEP09827.1 - 6.8e-19 67.7 0.0 1.7e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CEP09827.1 - 1e-09 38.4 0.1 2.5e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 CEP09827.1 - 1.8e-07 31.0 0.0 4.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CEP09827.1 - 8.8e-06 25.6 0.0 4.9e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 S1 domain DUF4550 PF15084.6 CEP09827.1 - 0.92 10.0 4.2 9.4 6.7 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Ribos_L4_asso_C PF14374.6 CEP09827.1 - 3.5 7.8 5.4 0.62 10.2 0.8 2.0 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain HTH_32 PF13565.6 CEP09828.1 - 0.0037 17.8 0.0 0.0063 17.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CEP09828.1 - 0.055 13.3 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 CEP09828.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Chromo PF00385.24 CEP09829.1 - 3.8e-10 39.5 0.6 6.4e-10 38.8 0.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP09829.1 - 0.00068 19.5 1.7 0.0045 16.8 0.3 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Phage_int_SAM_4 PF13495.6 CEP09831.1 - 0.052 14.0 0.1 0.076 13.5 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 CEP09831.1 - 0.067 13.5 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain rve PF00665.26 CEP09833.1 - 1.3e-10 41.5 0.0 1.4e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.15 CEP09833.1 - 0.004 16.9 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage Mu transposase DUF2887 PF11103.8 CEP09835.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) Transposase_31 PF04754.12 CEP09835.1 - 0.021 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative transposase, YhgA-like PDDEXK_2 PF12784.7 CEP09835.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase RVT_1 PF00078.27 CEP09836.1 - 3.5e-05 23.4 0.0 6.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP09838.1 - 3.7e-18 65.9 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 CEP09840.1 - 4.1e-06 26.5 3.2 4.1e-06 26.5 3.2 1.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 CEP09840.1 - 3.6e-05 23.6 2.6 6.5e-05 22.8 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEP09840.1 - 0.49 10.2 3.7 0.78 9.5 3.7 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger Nmad5 PF18757.1 CEP09841.1 - 0.073 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 RVT_1 PF00078.27 CEP09842.1 - 0.0013 18.3 0.4 0.004 16.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP09843.1 - 4.4e-07 30.4 0.1 1e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP09843.1 - 1.1e-06 29.1 0.1 2.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 CEP09843.1 - 7.6e-05 22.5 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Alba PF01918.21 CEP09843.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Alba FlaG PF03646.15 CEP09843.1 - 0.091 12.9 1.4 0.11 12.6 0.3 1.8 2 0 0 2 2 2 0 FlaG protein Asp_protease PF09668.10 CEP09843.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Mito_fiss_reg PF05308.11 CEP09844.1 - 0.03 14.4 4.6 0.043 13.9 4.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Stc1 PF12898.7 CEP09845.1 - 0.02 15.4 2.3 0.56 10.8 0.4 2.6 2 0 0 2 2 2 0 Stc1 domain zf-C2HC_2 PF13913.6 CEP09845.1 - 0.033 14.1 4.9 0.097 12.6 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Dof PF02701.15 CEP09845.1 - 0.063 13.4 0.5 0.063 13.4 0.5 2.4 3 0 0 3 3 3 0 Dof domain, zinc finger zf-CHY PF05495.12 CEP09845.1 - 0.063 13.8 2.8 5.4 7.6 0.2 2.5 2 1 0 2 2 2 0 CHY zinc finger PHD_4 PF16866.5 CEP09845.1 - 0.07 13.2 2.3 3.7 7.7 0.1 2.6 2 0 0 2 2 2 0 PHD-finger PHD_Oberon PF07227.11 CEP09845.1 - 0.2 11.5 3.2 5 7.0 0.0 2.6 2 1 0 2 2 2 0 PHD - plant homeodomain finger protein Zn_Tnp_IS1595 PF12760.7 CEP09845.1 - 0.31 11.0 3.7 0.42 10.6 1.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 CEP09845.1 - 0.58 9.9 5.2 1.1 9.0 0.2 2.8 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2318 PF10080.9 CEP09845.1 - 1.2 9.3 5.2 6 7.1 0.1 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) GAS PF13851.6 CEP09846.1 - 0.012 15.0 1.4 0.012 15.0 1.4 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 CEP09846.1 - 0.067 13.8 2.1 0.066 13.8 2.1 1.1 1 0 0 1 1 1 0 SlyX DUF5613 PF18467.1 CEP09847.1 - 0.03 14.7 1.2 4 7.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5613) NUDE_C PF04880.13 CEP09848.1 - 0.00084 19.9 7.6 0.00084 19.9 7.6 2.0 1 1 1 2 2 2 1 NUDE protein, C-terminal conserved region DUF2009 PF09418.10 CEP09848.1 - 0.023 13.8 4.9 0.025 13.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Fmp27_WPPW PF10359.9 CEP09848.1 - 0.026 13.4 11.9 0.032 13.1 11.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Phage_HK97_TLTM PF06120.11 CEP09848.1 - 0.077 12.2 13.0 0.1 11.8 13.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Thioredoxin_4 PF13462.6 CEP09848.1 - 0.33 11.1 5.7 0.52 10.4 5.7 1.3 1 0 0 1 1 1 0 Thioredoxin LMBR1 PF04791.16 CEP09848.1 - 0.41 9.5 8.7 0.47 9.3 8.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4065 PF13274.6 CEP09848.1 - 0.45 11.4 8.2 0.68 10.8 7.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) Guanylin PF02058.15 CEP09848.1 - 1.8 9.1 5.1 6.7 7.3 3.7 2.2 1 1 1 2 2 2 0 Guanylin precursor RNase_HII PF01351.18 CEP09848.1 - 2.5 7.9 7.2 3.3 7.5 7.2 1.1 1 0 0 1 1 1 0 Ribonuclease HII TMPIT PF07851.13 CEP09848.1 - 4.9 6.3 10.8 5.8 6.1 10.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3837 PF12939.7 CEP09848.1 - 5.8 7.4 11.3 8.5 6.8 9.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) DUF3450 PF11932.8 CEP09848.1 - 9.1 5.5 15.4 14 4.9 15.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Ank_5 PF13857.6 CEP09849.1 - 1.1e-11 44.7 0.0 5.6e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEP09849.1 - 2.3e-07 31.0 0.0 1.3e-05 25.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CEP09849.1 - 1.4e-06 28.8 0.0 4.3e-06 27.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP09849.1 - 5.1e-05 23.7 0.0 0.002 18.7 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP09849.1 - 8.8e-05 22.6 0.0 0.00075 19.8 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_C65 PF10275.9 CEP09852.1 - 0.0021 17.6 0.6 0.0037 16.7 0.3 1.5 1 1 0 1 1 1 1 Peptidase C65 Otubain PIF1 PF05970.14 CEP09853.1 - 8e-57 193.1 0.0 9.1e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP09853.1 - 3.8e-09 36.5 0.0 5.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEP09853.1 - 0.0032 17.5 0.1 0.026 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CEP09853.1 - 0.0068 16.7 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP09853.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.25 CEP09859.1 - 1.1e-52 178.8 0.0 1.2e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 CEP09859.1 - 0.0028 17.6 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 CEP09859.1 - 0.0033 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CEP09859.1 - 0.0044 16.3 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CEP09859.1 - 0.005 17.2 0.1 0.018 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CEP09859.1 - 0.028 14.8 0.0 0.071 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CEP09859.1 - 0.045 14.1 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CEP09859.1 - 0.075 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 CEP09859.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CEP09859.1 - 0.11 12.8 0.3 0.25 11.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP09859.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEP09859.1 - 0.17 11.1 0.0 0.49 9.6 0.1 1.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CEP09859.1 - 0.18 12.1 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CEP09859.1 - 0.18 10.7 0.2 0.26 10.2 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 CEP09859.1 - 0.19 11.8 0.1 5 7.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP09859.1 - 0.26 10.8 0.1 0.26 10.8 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NARG2_C PF10505.9 CEP09862.1 - 0.018 14.6 0.4 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus SR-25 PF10500.9 CEP09863.1 - 0.0049 16.5 10.3 0.011 15.4 10.3 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.19 CEP09864.1 - 3.1e-74 250.3 0.2 5.2e-74 249.6 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CEP09864.1 - 0.002 17.4 1.6 0.49 9.6 0.1 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 CEP09864.1 - 0.0031 17.6 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 CEP09864.1 - 0.007 16.6 0.1 0.02 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP09864.1 - 0.013 14.7 0.1 0.027 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CEP09864.1 - 0.027 13.2 0.3 0.052 12.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 CEP09864.1 - 0.03 14.8 0.2 0.13 12.7 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CEP09864.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEP09864.1 - 0.058 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 CEP09864.1 - 0.07 12.5 0.7 0.15 11.4 0.5 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP09864.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CEP09864.1 - 0.14 12.7 0.3 0.9 10.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase B12D PF06522.11 CEP09865.1 - 7.4e-19 67.3 0.0 8.8e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF5423 PF17461.2 CEP09865.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) COX7a PF02238.15 CEP09865.1 - 0.053 13.9 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII NUDIX PF00293.28 CEP09866.1 - 5.5e-10 39.4 0.0 9.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.6 CEP09866.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 DBC1 PAP2_3 PF14378.6 CEP09867.1 - 1.3e-22 80.5 9.4 2.2e-22 79.7 9.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 CEP09867.1 - 1.5e-05 24.8 9.6 1.5e-05 24.8 9.6 2.1 1 1 0 2 2 2 1 PAP2 superfamily BNIP3 PF06553.12 CEP09867.1 - 0.054 13.2 0.4 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 BNIP3 LTV PF04180.14 CEP09868.1 - 4.3e-84 283.5 29.6 4.3e-84 283.5 29.6 2.9 1 1 2 3 3 3 2 Low temperature viability protein TUDOR_5 PF18359.1 CEP09868.1 - 0.027 14.2 0.5 0.055 13.2 0.5 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 FUSC PF04632.12 CEP09869.1 - 7.1 5.0 6.1 5.8 5.3 3.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Arrestin_C PF02752.22 CEP09870.1 - 1e-14 55.2 6.0 7.8e-10 39.3 3.1 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP09870.1 - 3.3e-12 46.7 0.1 6.2e-09 36.1 0.0 3.3 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP09870.1 - 0.00014 21.6 0.2 0.00032 20.5 0.1 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like Cwf_Cwc_15 PF04889.12 CEP09870.1 - 0.38 10.4 7.6 6.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 CEP09870.1 - 1.6 8.8 8.4 13 5.8 0.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein SGT1 PF07093.11 CEP09871.1 - 4.2e-121 405.2 24.2 5.7e-106 355.3 0.2 3.0 1 1 1 2 2 2 2 SGT1 protein DUF3670 PF12419.8 CEP09871.1 - 0.0067 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 Helicase protein DUF1451 PF07295.11 CEP09871.1 - 1.3 9.1 4.5 0.41 10.7 0.3 2.3 2 1 1 3 3 3 0 Zinc-ribbon containing domain SNARE PF05739.19 CEP09872.1 - 0.0011 18.9 0.4 0.0025 17.7 0.4 1.6 1 0 0 1 1 1 1 SNARE domain Spectrin PF00435.21 CEP09872.1 - 0.016 15.7 3.5 0.016 15.7 3.5 3.1 3 1 0 3 3 3 0 Spectrin repeat DUF4183 PF13799.6 CEP09872.1 - 0.046 13.5 3.9 0.13 12.1 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) Syntaxin-18_N PF10496.9 CEP09872.1 - 0.073 13.3 0.8 0.073 13.3 0.8 3.3 3 1 1 4 4 4 0 SNARE-complex protein Syntaxin-18 N-terminus Goodbye PF17109.5 CEP09872.1 - 0.84 10.1 6.3 0.67 10.4 0.8 2.8 2 2 1 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF948 PF06103.11 CEP09872.1 - 1.2 9.4 12.7 4.5 7.6 1.1 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 CEP09872.1 - 4.3 6.9 25.8 8.2 6.0 19.1 3.4 2 1 1 3 3 3 0 Syntaxin FlaC_arch PF05377.11 CEP09872.1 - 8.2 6.9 7.9 3 8.3 0.5 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) SAP PF02037.27 CEP09873.1 - 1.9e-10 40.3 0.2 3.5e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 SAP domain SR-25 PF10500.9 CEP09873.1 - 2.4 7.7 21.3 0.79 9.3 14.3 2.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_25 PF13649.6 CEP09874.1 - 2e-15 57.3 0.0 4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP09874.1 - 5.3e-13 49.4 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP09874.1 - 4e-12 46.2 0.1 2.5e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP09874.1 - 1.2e-08 35.0 0.1 2.4e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP09874.1 - 6.1e-06 26.9 0.0 2.7e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP09874.1 - 1.4e-05 24.5 0.2 0.00034 20.0 0.2 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CEP09874.1 - 7e-05 22.8 0.0 0.00039 20.4 0.0 2.1 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 CEP09874.1 - 0.0007 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 CEP09874.1 - 0.0067 16.0 0.0 0.029 13.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 CEP09874.1 - 0.011 14.4 0.0 0.038 12.5 0.0 1.6 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 CEP09874.1 - 0.013 15.7 0.0 0.034 14.2 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 CEP09874.1 - 0.013 14.8 0.1 0.038 13.3 0.1 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CEP09874.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 CEP09874.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 CEP09874.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Metallophos PF00149.28 CEP09875.1 - 1.3e-11 45.4 0.8 2.9e-11 44.2 0.8 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PNRC PF15365.6 CEP09876.1 - 1.7e-08 34.0 6.2 3.5e-08 33.0 6.2 1.6 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif TFIIA PF03153.13 CEP09876.1 - 0.17 11.8 19.5 0.23 11.4 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 CEP09876.1 - 4.6 6.9 15.0 1 9.0 4.0 2.4 1 1 1 2 2 2 0 FAM176 family CAP_GLY PF01302.25 CEP09877.1 - 6.7e-23 80.5 0.4 1e-22 79.9 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain MS_channel PF00924.18 CEP09877.1 - 0.001 18.6 0.1 0.001 18.6 0.1 2.1 3 0 0 3 3 3 1 Mechanosensitive ion channel Wtap PF17098.5 CEP09877.1 - 0.0091 15.9 5.3 0.0091 15.9 5.3 2.9 2 2 1 3 3 3 1 WTAP/Mum2p family Phage_int_SAM_6 PF18644.1 CEP09877.1 - 0.061 13.3 3.1 0.32 11.0 0.1 2.5 1 1 1 2 2 2 0 Phage integrase SAM-like domain DUF2856 PF11043.8 CEP09877.1 - 0.28 11.3 1.1 2.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) FAM184 PF15665.5 CEP09877.1 - 1.7 8.4 24.4 13 5.5 24.3 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Acyl-CoA_dh_1 PF00441.24 CEP09878.1 - 1.5e-39 135.6 0.0 2.5e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CEP09878.1 - 8.9e-23 80.2 0.0 1.8e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CEP09878.1 - 1.7e-22 79.4 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEP09878.1 - 3.5e-17 63.1 0.0 7.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP09878.1 - 2.2e-07 31.2 0.0 3.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VPS11_C PF12451.8 CEP09879.1 - 3.6e-15 55.9 1.0 8.6e-15 54.7 1.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 CEP09879.1 - 6.7e-13 48.7 13.9 4.2e-12 46.1 2.9 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 CEP09879.1 - 6.1e-08 32.6 6.0 1.4e-07 31.4 6.0 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CEP09879.1 - 0.011 15.5 5.9 0.022 14.6 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FKBP_N_2 PF18023.1 CEP09879.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Vps8 PF12816.7 CEP09879.1 - 0.1 12.1 3.7 3.5 7.1 0.9 2.5 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 TMF_DNA_bd PF12329.8 CEP09879.1 - 0.11 12.5 4.1 0.42 10.6 4.1 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-RING_5 PF14634.6 CEP09879.1 - 0.29 11.1 5.9 0.54 10.3 5.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CEP09879.1 - 0.3 11.4 6.3 0.58 10.5 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 CEP09879.1 - 1.4 9.3 4.7 2.9 8.2 4.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 CEP09880.1 - 2.8e-13 50.1 2.0 0.0002 22.1 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Bul1_N PF04425.12 CEP09880.1 - 0.049 12.4 0.1 0.049 12.4 0.1 1.6 2 0 0 2 2 2 0 Bul1 N terminus DUF3446 PF11928.8 CEP09880.1 - 1.3 9.4 21.7 0.46 10.8 4.4 4.1 4 0 0 4 4 4 0 Early growth response N-terminal domain SPT2 PF08243.11 CEP09880.1 - 1.5 9.4 16.0 1.3 9.6 4.1 2.5 2 0 0 2 2 2 0 SPT2 chromatin protein 7tm_3 PF00003.22 CEP09881.1 - 1.9e-34 119.4 28.6 3e-34 118.8 28.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 CEP09881.1 - 7.1e-21 74.7 1.1 2.7e-20 72.8 1.1 2.0 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CEP09881.1 - 1.3e-10 41.5 1.5 1.2e-09 38.3 1.5 2.0 1 1 0 1 1 1 1 Periplasmic binding protein P53_tetramer PF07710.11 CEP09881.1 - 0.037 13.4 0.1 0.073 12.4 0.1 1.5 1 0 0 1 1 1 0 P53 tetramerisation motif Glyco_tran_WecB PF03808.13 CEP09881.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DIL PF01843.19 CEP09882.1 - 4.2e-28 97.6 7.7 2e-27 95.5 7.7 2.3 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CEP09882.1 - 7.3e-16 58.5 0.1 1.9e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP09882.1 - 1.4e-13 51.0 0.2 6.1e-07 29.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP09882.1 - 1.2e-12 47.8 0.0 2.6e-07 30.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP09882.1 - 1.4e-10 41.1 0.6 4.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEP09882.1 - 3.2e-07 30.1 0.1 0.0094 16.4 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Diphthamide_syn PF01866.17 CEP09883.1 - 3.1e-119 397.9 0.0 4e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SUR7 PF06687.12 CEP09883.1 - 1e-08 35.1 0.1 1.7e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CEP09883.1 - 0.097 12.6 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 HSP70 PF00012.20 CEP09885.1 - 0.00081 17.7 0.1 0.0012 17.2 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein ELMO_CED12 PF04727.13 CEP09887.1 - 2.7e-35 122.1 4.1 5.4e-35 121.1 0.2 2.8 3 0 0 3 3 3 1 ELMO/CED-12 family DUF3361 PF11841.8 CEP09887.1 - 1.6e-33 115.8 0.8 3.5e-33 114.7 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) PH_12 PF16457.5 CEP09887.1 - 1.9e-31 109.4 0.0 5.2e-31 108.0 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain F_actin_cap_B PF01115.17 CEP09887.1 - 0.023 14.3 0.1 0.06 13.0 0.1 1.6 2 0 0 2 2 2 0 F-actin capping protein, beta subunit SeleniumBinding PF11524.8 CEP09887.1 - 0.18 12.3 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 Selenium binding protein RTP1_C1 PF10363.9 CEP09887.1 - 0.22 11.7 1.3 0.53 10.5 1.3 1.7 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Filament PF00038.21 CEP09888.1 - 0.00021 21.0 27.9 0.0004 20.1 13.8 13.1 1 1 10 11 11 11 8 Intermediate filament protein NPV_P10 PF05531.12 CEP09888.1 - 0.44 11.0 0.1 0.44 11.0 0.1 19.1 3 1 14 17 17 17 0 Nucleopolyhedrovirus P10 protein zf-RVT PF13966.6 CEP09889.1 - 6.8e-07 29.9 2.9 6.8e-07 29.9 2.9 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF3222 PF11519.8 CEP09894.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) DNA_pol_A_exo1 PF01612.20 CEP09895.1 - 5.9e-10 39.1 0.1 2.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease DDE_3 PF13358.6 CEP09896.1 - 3.6e-13 49.5 0.0 1.3e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 CEP09898.1 - 3.6e-13 49.5 0.0 1.3e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease Helitron_like_N PF14214.6 CEP09900.1 - 5e-26 92.1 0.0 6.2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_3 PF13358.6 CEP09902.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.14 CEP09903.1 - 0.0082 15.4 0.0 0.021 14.0 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase HTH_32 PF13565.6 CEP09904.1 - 0.012 16.2 0.0 0.077 13.6 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CEP09904.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_1 PF00126.27 CEP09904.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Senescence_reg PF04520.13 CEP09904.1 - 0.16 12.8 1.6 0.2 12.5 1.2 1.4 1 1 0 1 1 1 0 Senescence regulator WAPL PF07814.13 CEP09907.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin RVT_1 PF00078.27 CEP09910.1 - 5.3e-23 81.7 0.0 6.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRP-S24 PF14955.6 CEP09912.1 - 0.062 13.3 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 rve PF00665.26 CEP09913.1 - 8.3e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF4046 PF13255.6 CEP09913.1 - 0.14 12.8 0.2 0.8 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4046) DDE_Tnp_1 PF01609.21 CEP09914.1 - 0.019 14.6 0.0 0.019 14.6 0.0 1.0 1 0 0 1 1 1 0 Transposase DDE domain DDE_5 PF13546.6 CEP09914.1 - 0.042 13.2 0.0 0.042 13.2 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.6 CEP09915.1 - 3.4e-06 26.6 0.0 3.8e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 IL10 PF00726.17 CEP09915.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin 10 E1-E2_ATPase PF00122.20 CEP09916.1 - 2.2e-41 141.4 1.9 2.2e-41 141.4 1.9 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP09916.1 - 9.4e-41 139.5 5.9 9.4e-41 139.5 5.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP09916.1 - 1.4e-20 73.2 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP09916.1 - 2.8e-20 73.5 0.1 3.5e-09 37.3 0.0 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP09916.1 - 4.2e-08 32.8 0.3 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP09916.1 - 9.8e-05 22.2 0.2 0.00019 21.2 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP09916.1 - 0.061 13.7 0.0 5.7 7.3 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 CEP09916.1 - 0.49 10.2 3.6 0.42 10.4 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) UpxZ PF06603.11 CEP09917.1 - 0.0061 16.8 0.0 0.0068 16.7 0.0 1.1 1 0 0 1 1 1 1 UpxZ family of transcription anti-terminator antagonists SPT2 PF08243.11 CEP09918.1 - 1.3e-19 70.8 21.0 1.3e-19 70.8 21.0 3.9 3 1 0 3 3 3 1 SPT2 chromatin protein ABC_tran PF00005.27 CEP09919.1 - 6.7e-33 114.1 1.2 4.4e-18 66.1 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CEP09919.1 - 5.1e-12 46.2 0.1 0.004 17.0 0.0 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP09919.1 - 1.1e-08 34.8 0.0 0.073 12.5 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CEP09919.1 - 5.9e-08 32.8 0.0 0.0012 18.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA PF00004.29 CEP09919.1 - 6.3e-08 33.1 0.1 0.039 14.4 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CEP09919.1 - 1.6e-07 31.7 0.0 0.029 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEP09919.1 - 1.6e-07 31.6 0.0 0.079 13.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CEP09919.1 - 2.4e-07 31.5 0.8 0.021 15.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CEP09919.1 - 4.5e-07 29.5 0.1 0.021 14.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEP09919.1 - 5.1e-07 29.8 0.0 0.0047 17.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CEP09919.1 - 1.2e-06 29.1 0.0 0.034 14.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CEP09919.1 - 3.7e-06 27.4 0.3 0.038 14.4 0.0 3.1 4 0 0 4 4 2 2 AAA ATPase domain RNA_helicase PF00910.22 CEP09919.1 - 1.5e-05 25.3 0.0 0.27 11.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 CEP09919.1 - 1.7e-05 24.8 0.0 0.17 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 CEP09919.1 - 2.6e-05 23.4 0.1 0.2 10.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Chromo PF00385.24 CEP09919.1 - 2.7e-05 24.0 1.1 0.00027 20.8 0.3 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 CEP09919.1 - 3.3e-05 23.9 0.0 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 NACHT domain HEAT PF02985.22 CEP09919.1 - 0.0002 21.3 6.8 6.6 7.3 0.0 5.3 5 0 0 5 5 4 0 HEAT repeat DUF815 PF05673.13 CEP09919.1 - 0.0002 20.6 0.0 0.49 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CEP09919.1 - 0.00032 20.5 0.0 0.32 10.7 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CEP09919.1 - 0.00035 20.7 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CEP09919.1 - 0.00049 20.3 0.3 0.22 11.6 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain Rad17 PF03215.15 CEP09919.1 - 0.0014 18.6 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CEP09919.1 - 0.0017 18.4 0.0 0.72 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 CEP09919.1 - 0.002 18.0 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 CEP09919.1 - 0.0022 18.3 0.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CEP09919.1 - 0.0028 17.4 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Vac14_Fab1_bd PF12755.7 CEP09919.1 - 0.0028 18.2 0.2 1.4 9.6 0.0 3.4 3 1 1 4 4 2 1 Vacuolar 14 Fab1-binding region 4HB PF17947.1 CEP09919.1 - 0.0029 17.6 0.0 0.012 15.6 0.0 2.1 1 0 0 1 1 1 1 Four helical bundle domain ATP-synt_ab PF00006.25 CEP09919.1 - 0.0032 17.1 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain TAF6_C PF07571.13 CEP09919.1 - 0.0041 17.4 0.1 0.014 15.7 0.1 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain AAA_27 PF13514.6 CEP09919.1 - 0.0042 16.7 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP09919.1 - 0.0071 15.9 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CEP09919.1 - 0.0088 15.3 0.0 0.93 8.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 CEP09919.1 - 0.012 15.3 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CEP09919.1 - 0.016 15.3 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 CEP09919.1 - 0.016 15.1 0.2 3.1 7.7 0.0 2.9 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CEP09919.1 - 0.021 14.6 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CEP09919.1 - 0.033 13.5 0.1 10 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 CEP09919.1 - 0.036 12.7 0.8 4.8 5.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CEP09919.1 - 0.038 13.9 0.1 4.1 7.3 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 CEP09919.1 - 0.044 13.3 0.0 6 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CEP09919.1 - 0.048 13.4 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 CEP09919.1 - 0.052 13.5 0.3 17 5.4 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CEP09919.1 - 0.061 13.1 0.0 20 4.9 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein TsaE PF02367.17 CEP09919.1 - 0.068 13.2 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 CEP09919.1 - 0.07 12.7 0.0 5.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DRIM PF07539.12 CEP09919.1 - 0.074 11.3 0.0 0.35 9.1 0.0 1.7 1 1 0 1 1 1 0 Down-regulated in metastasis Roc PF08477.13 CEP09919.1 - 0.1 12.8 0.0 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HEAT_EZ PF13513.6 CEP09919.1 - 0.52 10.9 2.3 36 5.0 0.1 3.9 3 1 0 3 3 3 0 HEAT-like repeat DAGK_cat PF00781.24 CEP09920.1 - 0.005 16.4 0.2 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain PIF1 PF05970.14 CEP09923.1 - 2.2e-26 92.9 0.0 3.5e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP09923.1 - 0.00017 19.7 0.0 0.00026 19.1 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP09923.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AlaDh_PNT_C PF01262.21 CEP09924.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FTCD_C PF04961.12 CEP09927.1 - 0.015 15.0 0.2 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF533 PF04391.12 CEP09927.1 - 0.052 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gar1 PF04410.14 CEP09928.1 - 6e-38 130.0 0.1 6e-38 130.0 0.1 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MRI PF15325.6 CEP09928.1 - 0.078 14.1 9.4 0.57 11.3 0.5 2.7 2 0 0 2 2 2 0 Modulator of retrovirus infection Uds1 PF15456.6 CEP09928.1 - 0.2 11.8 5.8 0.29 11.3 0.8 2.3 1 1 1 2 2 2 0 Up-regulated During Septation SR-25 PF10500.9 CEP09928.1 - 1.8 8.1 11.3 0.14 11.8 2.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PNISR PF15996.5 CEP09928.1 - 5.9 7.1 7.4 2 8.7 0.8 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Cwf_Cwc_15 PF04889.12 CEP09928.1 - 9.1 5.9 15.9 3.5 7.3 3.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AAA_2 PF07724.14 CEP09929.1 - 1.8e-40 138.9 0.3 3.9e-39 134.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEP09929.1 - 1.9e-15 57.5 0.1 5.3e-15 56.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CEP09929.1 - 7.3e-09 35.6 0.3 7.3e-09 35.6 0.3 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CEP09929.1 - 4.1e-07 30.1 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEP09929.1 - 2.3e-06 27.2 3.3 0.00058 19.3 0.1 3.8 2 2 2 4 4 4 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CEP09929.1 - 6.6e-05 22.7 0.0 0.02 14.6 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CEP09929.1 - 7.9e-05 23.0 3.4 0.00085 19.6 0.2 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CEP09929.1 - 0.00016 21.5 0.3 0.0039 17.0 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CEP09929.1 - 0.00037 20.3 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 CEP09929.1 - 0.00077 19.2 0.3 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEP09929.1 - 0.0016 18.9 0.8 0.011 16.3 0.0 2.6 3 0 0 3 3 2 1 ABC transporter MCM PF00493.23 CEP09929.1 - 0.0025 17.0 0.1 0.017 14.2 0.1 2.1 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 CEP09929.1 - 0.0029 18.0 2.3 0.01 16.2 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CEP09929.1 - 0.0034 17.4 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP09929.1 - 0.0042 17.2 0.4 0.042 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEP09929.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CEP09929.1 - 0.0059 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CEP09929.1 - 0.0059 16.7 0.0 0.023 14.8 0.0 2.0 2 1 0 2 2 1 1 Sigma-54 interaction domain TsaE PF02367.17 CEP09929.1 - 0.0091 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CEP09929.1 - 0.011 15.2 0.1 0.03 13.8 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CEP09929.1 - 0.018 14.9 0.0 0.075 12.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 CEP09929.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 CEP09929.1 - 0.05 13.6 0.5 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 CEP09929.1 - 0.054 13.3 0.0 0.15 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CEP09929.1 - 0.12 12.7 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Swi3 PF07962.12 CEP09930.1 - 1.4e-10 41.0 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Ribosomal_L37ae PF01780.19 CEP09932.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CEP09932.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CEP09932.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 CEP09932.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 CEP09932.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 CEP09932.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 CEP09932.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 CEP09932.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CEP09932.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_60s PF00428.19 CEP09933.1 - 3.2e-23 82.1 6.9 3.9e-23 81.9 6.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FA_hydroxylase PF04116.13 CEP09934.1 - 2e-22 79.9 7.4 9e-22 77.8 7.4 2.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily 5_nucleotid_C PF02872.18 CEP09935.1 - 3.6e-36 124.8 0.0 1e-35 123.3 0.0 1.8 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CEP09935.1 - 8.4e-07 29.7 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HSP20 PF00011.21 CEP09936.1 - 6.7e-18 64.7 0.2 5.3e-11 42.6 0.1 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CEP09936.1 - 1e-06 28.2 0.0 4.6e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Thiolase_N PF00108.23 CEP09937.1 - 1.1e-18 67.6 0.3 4.8e-17 62.2 0.2 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP09937.1 - 1.2e-12 47.6 0.1 4.5e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 CEP09937.1 - 2.4e-05 24.3 0.1 0.024 14.6 0.0 3.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CEP09937.1 - 0.00017 21.2 4.7 0.027 14.1 1.1 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEP09937.1 - 0.0012 18.6 0.8 0.039 13.8 0.4 2.9 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 CEP09937.1 - 0.0083 14.9 0.4 0.82 8.3 0.1 2.3 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) HMG_CoA_synt_N PF01154.17 CEP09937.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Spectrin PF00435.21 CEP09940.1 - 0.063 13.8 3.3 0.078 13.5 0.3 2.1 2 0 0 2 2 2 0 Spectrin repeat Type_III_YscX PF09474.10 CEP09940.1 - 0.064 13.6 1.9 0.12 12.7 1.1 1.8 1 1 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) BCL_N PF04714.13 CEP09941.1 - 0.0025 17.8 0.8 0.0046 17.0 0.8 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region ANAPC4_WD40 PF12894.7 CEP09942.1 - 6.8e-10 39.1 0.3 0.01 16.1 0.0 3.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP09942.1 - 1.9e-06 27.9 0.8 0.018 14.9 0.1 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CEP09942.1 - 5.7e-06 26.1 1.4 0.15 12.0 0.1 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 CEP09942.1 - 0.00063 20.5 4.3 15 6.7 0.1 5.8 5 1 0 5 5 5 1 WD domain, G-beta repeat IKI3 PF04762.12 CEP09942.1 - 0.082 10.9 0.3 0.31 9.0 0.2 1.9 1 1 0 1 1 1 0 IKI3 family zf-RING_2 PF13639.6 CEP09943.1 - 2.1e-12 47.2 11.3 3.4e-12 46.5 11.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP09943.1 - 4.1e-10 39.2 4.5 7.7e-10 38.3 4.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEP09943.1 - 2e-09 37.2 10.7 3.3e-09 36.4 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP09943.1 - 9.6e-07 29.0 9.4 2.1e-06 27.9 9.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEP09943.1 - 3.2e-06 27.0 3.0 3.2e-06 27.0 3.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP09943.1 - 5.6e-06 26.1 9.2 9.5e-06 25.4 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP09943.1 - 1.6e-05 24.8 8.7 2.5e-05 24.1 8.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEP09943.1 - 0.00053 19.8 8.8 0.00087 19.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CEP09943.1 - 0.0015 18.3 4.4 0.0032 17.3 4.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 CEP09943.1 - 0.0045 16.6 8.0 0.007 16.0 8.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CEP09943.1 - 0.011 15.8 8.6 0.052 13.6 8.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEP09943.1 - 0.02 14.8 10.1 0.035 14.0 10.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEP09943.1 - 0.037 14.2 8.0 0.074 13.2 8.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CEP09943.1 - 0.62 10.2 10.0 2.2 8.4 10.0 1.9 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_5 PF17121.5 CEP09943.1 - 0.91 9.5 5.2 1.9 8.4 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Blt1 PF12754.7 CEP09943.1 - 4.7 7.5 6.9 6.9 7.0 5.9 1.8 1 1 0 1 1 1 0 Blt1 N-terminal domain RINGv PF12906.7 CEP09943.1 - 8.1 6.7 12.2 9.6 6.4 10.6 2.0 1 1 1 2 2 2 0 RING-variant domain Aminotran_1_2 PF00155.21 CEP09944.1 - 3e-41 141.8 0.0 4.9e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP09944.1 - 0.037 13.3 1.4 0.093 12.0 0.0 2.2 2 1 0 2 2 2 0 Beta-eliminating lyase RVT_1 PF00078.27 CEP09945.1 - 2.3e-10 40.3 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4261 PF14080.6 CEP09946.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) RHH_1 PF01402.21 CEP09946.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PS_Dcarbxylase PF02666.15 CEP09947.1 - 6e-47 159.8 0.3 4.4e-46 157.0 0.3 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase UPF0014 PF03649.13 CEP09949.1 - 6.1e-73 245.1 25.2 7.2e-73 244.9 25.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Ost5 PF05251.12 CEP09949.1 - 0.036 14.3 0.7 0.036 14.3 0.7 3.1 5 0 0 5 5 5 0 Oligosaccharyltransferase subunit 5 PIRT PF15099.6 CEP09949.1 - 0.24 11.0 2.4 0.57 9.8 0.5 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family KH_1 PF00013.29 CEP09950.1 - 3e-52 174.3 8.1 9.5e-19 67.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEP09950.1 - 7.2e-15 54.6 2.8 0.0013 18.5 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CEP09950.1 - 8.1e-10 38.4 2.8 0.016 15.0 0.0 3.6 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 CEP09950.1 - 0.0018 18.2 0.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 CEP09950.1 - 0.0063 16.6 1.4 3.6 7.8 0.0 3.4 3 0 0 3 3 3 1 NusA-like KH domain Methyltransf_31 PF13847.6 CEP09951.1 - 5.2e-12 45.8 0.0 7.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP09951.1 - 9.8e-12 44.7 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEP09951.1 - 6.1e-09 36.5 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 CEP09951.1 - 7.2e-07 28.8 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmC_N PF17827.1 CEP09951.1 - 2.4e-05 24.8 0.0 5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain Ubie_methyltran PF01209.18 CEP09951.1 - 4.1e-05 23.0 0.0 7.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP09951.1 - 5.9e-05 23.7 0.0 0.00017 22.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CEP09951.1 - 9e-05 22.2 0.0 0.0002 21.1 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 CEP09951.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEP09951.1 - 0.00032 20.6 0.0 0.00062 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP09951.1 - 0.00037 21.1 0.0 0.00083 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEP09951.1 - 0.00055 20.0 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 CEP09951.1 - 0.0007 19.1 0.3 0.0077 15.7 0.0 2.1 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_16 PF10294.9 CEP09951.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_10 PF05971.12 CEP09951.1 - 0.0053 16.1 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_15 PF09445.10 CEP09951.1 - 0.009 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 CEP09951.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.8 CEP09951.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 CEP09951.1 - 0.053 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 CEP09951.1 - 0.22 10.6 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RYDR_ITPR PF01365.21 CEP09953.1 - 0.092 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 RIH domain Exo_endo_phos_2 PF14529.6 CEP09954.1 - 9e-10 38.4 1.4 9.6e-10 38.3 0.2 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF4611 PF15387.6 CEP09957.1 - 0.0033 17.6 3.6 0.0064 16.7 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) FAD_binding_8 PF08022.12 CEP09958.1 - 2.1e-08 34.2 0.7 4.2e-07 30.0 0.7 2.2 1 1 0 1 1 1 1 FAD-binding domain RVT_1 PF00078.27 CEP09959.1 - 4.6e-07 29.6 0.1 1.3e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP09960.1 - 1.2e-08 35.6 0.1 2.5e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2_6 PF13912.6 CEP09963.1 - 0.024 14.7 0.8 0.059 13.4 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Pep1_7 PF17232.2 CEP09963.1 - 0.07 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Elicitor peptide 1-7 zf-C2H2_9 PF16293.5 CEP09963.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 CEP09963.1 - 0.16 12.9 1.5 0.41 11.6 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3419 PF11899.8 CEP09965.1 - 1.4e-15 57.4 0.1 4.2e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3419) DUF2537 PF10801.8 CEP09965.1 - 0.18 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) SH3_1 PF00018.28 CEP09966.1 - 4.2e-13 48.7 0.0 5.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP09966.1 - 1.8e-12 46.9 0.0 2.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP09966.1 - 1.4e-07 31.1 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP09966.1 - 0.00092 19.4 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain HTH_28 PF13518.6 CEP09969.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 CEP09973.1 - 2.4e-26 92.2 0.7 8e-24 84.1 0.1 2.9 2 1 0 2 2 2 1 DDE superfamily endonuclease PAPA-1 PF04795.12 CEP09974.1 - 0.21 12.4 5.0 0.11 13.3 2.9 1.7 1 1 0 1 1 1 0 PAPA-1-like conserved region Cu_amine_oxidN2 PF02727.16 CEP09976.1 - 0.00026 21.1 0.0 0.00031 20.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain INCENP_ARK-bind PF03941.15 CEP09976.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region RNA_binding PF01877.17 CEP09978.1 - 0.03 14.6 0.8 0.093 13.0 0.1 2.2 3 0 0 3 3 3 0 RNA binding Tox-REase-5 PF15648.6 CEP09978.1 - 0.48 11.0 2.9 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 5 Ketoacyl-synt_2 PF13723.6 CEP09979.1 - 0.44 10.1 6.7 0.59 9.7 6.7 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain FUSC PF04632.12 CEP09979.1 - 5.9 5.3 4.7 7.1 5.0 4.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Macoilin PF09726.9 CEP09981.1 - 8.4 4.8 9.3 8.6 4.8 9.3 1.0 1 0 0 1 1 1 0 Macoilin family zf-CCHC PF00098.23 CEP09982.1 - 9.7e-06 25.4 2.6 1.6e-05 24.7 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEP09982.1 - 5.7e-05 23.3 0.4 0.00013 22.1 0.3 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.6 CEP09982.1 - 0.071 13.1 1.4 0.18 11.8 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP09982.1 - 0.19 11.5 0.5 0.36 10.6 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle PIF1 PF05970.14 CEP09984.1 - 5.6e-11 42.2 0.4 1.3e-10 41.0 0.4 1.5 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 CEP09984.1 - 0.0027 17.5 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP09984.1 - 0.0071 14.3 0.0 0.011 13.6 0.0 1.3 1 0 0 1 1 1 1 Helicase Elf1 PF05129.13 CEP09985.1 - 0.13 12.3 5.4 0.066 13.3 1.0 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 CEP09985.1 - 0.54 11.2 10.1 0.61 11.1 4.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Lar_restr_allev PF14354.6 CEP09985.1 - 0.67 10.4 4.4 0.67 10.4 1.9 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar ssDNA_DBD PF18333.1 CEP09986.1 - 0.6 10.2 5.8 5.3 7.2 0.6 2.9 1 1 2 3 3 3 0 Non-canonical single-stranded DNA-binding domain zf-CCHC PF00098.23 CEP09987.1 - 0.00073 19.5 1.3 0.00073 19.5 1.3 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEP09987.1 - 0.0014 18.3 0.3 0.0027 17.4 0.3 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger Spexin PF15171.6 CEP09987.1 - 0.0076 16.4 0.3 0.014 15.5 0.3 1.4 1 0 0 1 1 1 1 Neuropeptide secretory protein family, NPQ, spexin zf-CCHC_2 PF13696.6 CEP09987.1 - 0.021 14.7 1.6 0.035 13.9 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle ANF_receptor PF01094.28 CEP09988.1 - 5.3e-39 134.3 0.4 5.3e-39 134.3 0.4 1.9 2 0 0 2 2 2 1 Receptor family ligand binding region DIL PF01843.19 CEP09988.1 - 6.7e-28 97.0 1.8 6.7e-28 97.0 1.8 2.7 2 0 0 2 2 1 1 DIL domain 7tm_3 PF00003.22 CEP09988.1 - 3.8e-25 89.0 17.9 4.6e-25 88.7 12.5 2.3 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 CEP09988.1 - 4e-16 59.6 1.2 4e-16 59.6 1.2 1.8 2 0 0 2 2 2 1 Periplasmic binding protein Ank_2 PF12796.7 CEP09988.1 - 9.1e-16 58.2 0.0 6.8e-15 55.4 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEP09988.1 - 1e-10 41.6 0.0 0.00023 21.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CEP09988.1 - 2.4e-08 33.6 0.0 0.037 14.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CEP09988.1 - 4.3e-08 33.3 0.0 0.0003 21.0 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP09988.1 - 7.1e-08 32.9 0.0 7.4e-07 29.6 0.0 2.5 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Suf PF05843.14 CEP09988.1 - 0.00045 20.3 6.7 0.00045 20.3 6.7 3.2 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) Ctr PF04145.15 CEP09988.1 - 0.098 13.3 4.4 2 9.0 2.0 3.6 2 0 0 2 2 2 0 Ctr copper transporter family Med15 PF09606.10 CEP09988.1 - 0.25 10.0 18.3 0.51 9.0 18.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4770 PF15994.5 CEP09988.1 - 3.5 7.8 11.6 0.84 9.9 2.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) COX15-CtaA PF02628.15 CEP09989.1 - 1.7e-102 342.8 1.5 2.1e-102 342.5 1.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RrnaAD PF00398.20 CEP09990.1 - 9.1e-67 224.9 0.1 1.2e-66 224.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEP09990.1 - 1.8e-06 28.6 0.0 3.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP09990.1 - 0.0003 21.4 0.0 0.00057 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEP09990.1 - 0.00045 20.0 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEP09990.1 - 0.0015 18.1 0.1 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CEP09990.1 - 0.0031 18.2 0.0 0.0067 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 CEP09990.1 - 0.0054 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 CEP09990.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 CEP09990.1 - 0.012 15.1 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 CEP09990.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 CEP09990.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CEP09990.1 - 0.065 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase Cons_hypoth95 PF03602.15 CEP09990.1 - 0.082 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.18 CEP09990.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PI31_Prot_N PF11566.8 CEP09991.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal GCV_H PF01597.19 CEP09991.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein IIGP PF05049.13 CEP09992.1 - 7.9e-29 100.8 0.0 1.1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CEP09992.1 - 2.2e-09 37.4 0.0 3.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP09992.1 - 0.0001 22.3 0.1 0.00079 19.4 0.0 2.0 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CEP09992.1 - 0.0001 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 CEP09992.1 - 0.00015 22.3 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 CEP09992.1 - 0.00019 21.6 0.0 0.0005 20.3 0.0 1.8 2 1 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CEP09992.1 - 0.0031 17.6 0.3 0.11 12.6 0.2 2.2 1 1 1 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 CEP09992.1 - 0.0057 16.0 0.0 0.0095 15.3 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.16 CEP09992.1 - 0.012 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 AIG1 family AAA_29 PF13555.6 CEP09992.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FUSC_2 PF13515.6 CEP09992.1 - 0.044 13.9 0.2 0.09 12.9 0.2 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like AAA_16 PF13191.6 CEP09992.1 - 0.045 14.1 0.0 0.088 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 CEP09992.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_7 PF12775.7 CEP09992.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SMC_N PF02463.19 CEP09992.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP09992.1 - 0.099 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEP09992.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF997 PF06196.12 CEP09992.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) AAA_28 PF13521.6 CEP09992.1 - 0.15 12.3 0.3 0.37 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain CsbD PF05532.12 CEP09993.1 - 3.6e-15 55.6 12.7 5.4e-12 45.4 0.5 2.0 1 1 1 2 2 2 2 CsbD-like BAMBI PF06211.12 CEP09994.1 - 1.3 9.3 5.4 0.24 11.7 1.2 1.9 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain zf-RING_2 PF13639.6 CEP09995.1 - 8.1e-14 51.7 5.2 1.5e-13 50.8 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP09995.1 - 2.1e-10 40.1 1.4 2.1e-10 40.1 1.4 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEP09995.1 - 1.2e-08 34.7 5.9 1.9e-08 34.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP09995.1 - 2.2e-08 33.8 5.3 3.7e-08 33.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP09995.1 - 6.3e-07 29.6 8.3 3.6e-06 27.2 8.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEP09995.1 - 9.9e-07 28.5 2.6 1.7e-06 27.7 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CEP09995.1 - 1.2e-06 28.4 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 CEP09995.1 - 1.8e-06 27.8 4.1 2.9e-06 27.1 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP09995.1 - 3.6e-06 26.9 2.9 0.00016 21.7 0.9 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP09995.1 - 8.1e-06 25.6 2.8 1.5e-05 24.7 2.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP09995.1 - 0.00023 21.2 3.6 0.00091 19.2 3.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEP09995.1 - 0.0011 18.7 3.9 0.002 17.8 3.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain UPF0542 PF15086.6 CEP09995.1 - 0.022 14.7 0.1 0.069 13.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 FANCL_C PF11793.8 CEP09995.1 - 0.031 14.5 5.4 0.35 11.1 5.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CEP09995.1 - 0.037 14.1 3.3 0.09 12.9 3.3 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 CEP09995.1 - 0.076 12.9 4.1 0.14 12.1 4.1 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CEP09995.1 - 0.083 12.5 2.9 0.16 11.6 2.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 CEP09995.1 - 0.085 12.9 3.3 0.29 11.2 3.3 1.9 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 CEP09995.1 - 0.54 10.6 4.2 0.98 9.8 4.2 1.5 1 0 0 1 1 1 0 RING-like domain Pkinase PF00069.25 CEP09996.1 - 3.3e-60 203.7 0.0 9e-60 202.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP09996.1 - 1e-33 116.7 0.0 1.5e-32 112.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP09996.1 - 9e-10 38.3 0.0 2.2e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP09996.1 - 1.9e-05 23.7 1.7 6.6e-05 21.8 0.1 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP09996.1 - 0.016 15.2 0.2 0.42 10.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribonuclease PF00545.20 CEP09996.1 - 0.11 13.3 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 ribonuclease NepR PF18557.1 CEP09996.1 - 2.4 7.9 5.0 0.58 9.9 1.2 2.0 2 0 0 2 2 2 0 Anti-sigma factor NepR E1_dh PF00676.20 CEP09997.1 - 6e-62 209.3 0.0 8.3e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CEP09997.1 - 2.8e-61 206.3 0.0 4.5e-61 205.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEP09997.1 - 1.5e-55 187.1 0.1 2.5e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CEP09997.1 - 3.2e-20 71.4 0.5 7.8e-20 70.2 0.5 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Imm70 PF15601.6 CEP09997.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 70 NSP2-B_epitope PF14757.6 CEP09997.1 - 0.055 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein GAPT PF11770.8 CEP09998.1 - 0.0038 17.1 0.1 0.0075 16.1 0.1 1.6 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) Toxin_29 PF08116.11 CEP09998.1 - 0.0038 17.2 1.3 0.009 16.0 1.3 1.6 1 0 0 1 1 1 1 PhTx neurotoxin family UPF0506 PF11703.8 CEP09998.1 - 0.032 14.6 8.0 0.056 13.8 8.0 1.4 1 0 0 1 1 1 0 UPF0506 EphA2_TM PF14575.6 CEP09998.1 - 0.032 15.1 1.3 0.036 14.9 0.3 1.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CRPA PF05745.11 CEP09998.1 - 0.095 12.7 0.7 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2561 PF10812.8 CEP09998.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) EB PF01683.18 CEP09998.1 - 0.14 12.5 10.0 0.41 11.0 9.9 1.8 1 1 1 2 2 2 0 EB module Dickkopf_N PF04706.12 CEP09998.1 - 0.46 11.0 9.5 0.87 10.1 9.5 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Shisa PF13908.6 CEP09998.1 - 0.59 10.3 9.8 1.3 9.2 9.7 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Conotoxin_I2 PF17557.2 CEP09998.1 - 7.8 6.7 8.2 0.26 11.4 1.8 1.8 2 0 0 2 2 2 0 I2-superfamily conotoxins Fur_reg_FbpB PF13040.6 CEP09999.1 - 3.6 7.2 6.7 5.2 6.7 0.4 2.2 2 0 0 2 2 2 0 Fur-regulated basic protein B MIS13 PF08202.11 CEP10000.1 - 2e-07 30.6 2.9 0.004 16.5 0.0 2.6 1 1 2 3 3 3 2 Mis12-Mtw1 protein family Nop14 PF04147.12 CEP10001.1 - 0.047 11.9 2.1 0.048 11.9 2.1 1.0 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.18 CEP10002.1 - 2.2e-48 165.0 17.6 2.7e-48 164.7 17.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEP10002.1 - 4.2e-05 22.8 8.7 4.2e-05 22.8 8.7 1.8 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family CLASP_N PF12348.8 CEP10003.1 - 9.2e-25 87.5 0.0 3.6e-07 30.0 0.1 6.3 5 1 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 CEP10003.1 - 8.3e-11 41.2 15.3 0.32 11.4 0.1 10.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 CEP10003.1 - 2.9e-10 40.4 20.2 0.24 11.8 0.0 10.2 9 3 1 12 12 12 4 HEAT repeats HEAT_EZ PF13513.6 CEP10003.1 - 3.3e-05 24.3 11.1 0.86 10.2 0.2 7.9 7 0 0 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 CEP10003.1 - 0.00044 20.3 14.6 0.25 11.4 0.0 7.5 7 2 2 9 9 9 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEP10003.1 - 0.022 15.3 0.0 15 6.2 0.0 4.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF499 PF04465.12 CEP10003.1 - 0.046 11.5 0.1 0.096 10.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF499) GATA PF00320.27 CEP10004.1 - 0.31 10.7 22.3 0.11 12.1 8.9 3.3 2 1 0 2 2 2 0 GATA zinc finger DUF3425 PF11905.8 CEP10005.1 - 8.8e-14 51.5 0.5 8.8e-14 51.5 0.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEP10005.1 - 0.00016 21.7 10.4 0.00016 21.7 10.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor DUF5094 PF17015.5 CEP10005.1 - 0.054 13.6 0.3 0.054 13.6 0.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5094) HTH_Tnp_Tc5 PF03221.16 CEP10006.1 - 0.0043 17.1 0.0 0.0047 16.9 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Bee_toxin PF17454.2 CEP10007.1 - 0.28 11.3 3.8 1.1 9.3 3.8 2.0 1 1 0 1 1 1 0 Honey bee toxin DUF3425 PF11905.8 CEP10008.1 - 5.8e-10 39.2 0.2 3.2e-09 36.8 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 CEP10008.1 - 2.9 8.0 16.0 16 5.6 16.0 2.3 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CEP10008.1 - 6.3 7.0 20.0 0.98 9.6 14.2 2.6 2 1 0 2 2 2 0 bZIP transcription factor F-box-like PF12937.7 CEP10010.1 - 2.4e-05 24.1 0.5 4.4e-05 23.3 0.5 1.5 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 CEP10010.1 - 0.0006 19.7 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10010.1 - 0.0017 18.1 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10010.1 - 0.0039 16.8 0.1 0.0079 15.9 0.1 1.5 1 0 0 1 1 1 1 TPR repeat F-box PF00646.33 CEP10010.1 - 0.008 16.0 0.5 0.018 14.9 0.5 1.6 1 0 0 1 1 1 1 F-box domain TPR_12 PF13424.6 CEP10010.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat YL1 PF05764.13 CEP10011.1 - 1.8e-32 113.4 25.4 1.8e-32 113.4 25.4 1.7 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CEP10011.1 - 6.1e-14 51.5 0.7 1.1e-13 50.7 0.7 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Endostatin PF06482.11 CEP10012.1 - 0.00025 20.6 0.2 0.00032 20.3 0.2 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DPBB_1 PF03330.18 CEP10012.1 - 0.00041 20.6 0.2 0.0032 17.7 0.2 2.3 1 1 0 1 1 1 1 Lytic transglycolase GSH_synth_ATP PF03917.17 CEP10012.1 - 0.00054 18.8 0.1 0.00057 18.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Rtf2 PF04641.12 CEP10012.1 - 0.015 14.7 4.3 0.018 14.5 4.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Barwin PF00967.17 CEP10012.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Barwin family DUF755 PF05501.11 CEP10012.1 - 0.043 14.1 21.4 0.058 13.7 21.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 CEP10012.1 - 0.13 12.5 10.3 0.21 11.8 10.3 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NARP1 PF12569.8 CEP10012.1 - 0.13 11.1 3.2 0.16 10.8 3.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 CEP10012.1 - 0.34 9.6 4.7 0.43 9.3 4.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PRR22 PF15776.5 CEP10012.1 - 0.46 9.8 4.3 0.66 9.3 4.3 1.2 1 0 0 1 1 1 0 Proline-rich protein family 22 SNARE PF05739.19 CEP10013.1 - 0.98 9.5 3.1 2.6 8.1 0.9 2.3 2 1 0 2 2 2 0 SNARE domain CSN5_C PF18323.1 CEP10016.1 - 2.5e-26 92.4 1.0 4.6e-26 91.6 1.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 CEP10016.1 - 6.7e-25 87.4 1.7 3.7e-22 78.5 1.7 2.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEP10016.1 - 0.027 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DHR10 PF18595.1 CEP10017.1 - 0.0089 16.1 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Lzipper-MIP1 PF14389.6 CEP10017.1 - 0.036 14.4 0.2 0.084 13.2 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 CEP10017.1 - 0.045 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DAZAP2 PF11029.8 CEP10017.1 - 0.09 13.7 6.8 2.4 9.1 0.0 2.3 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) DUF5082 PF16888.5 CEP10017.1 - 0.097 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) betaPIX_CC PF16523.5 CEP10017.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 betaPIX coiled coil DDE_3 PF13358.6 CEP10018.1 - 1.5e-25 89.7 0.0 2.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_Ca_ex PF01699.24 CEP10019.1 - 9e-35 119.9 28.4 3.8e-20 72.4 13.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1103 PF06513.11 CEP10020.1 - 0.0054 16.4 1.5 0.0068 16.0 1.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) APG17 PF04108.12 CEP10021.1 - 9.9e-77 258.7 20.6 1.1e-76 258.5 20.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Vps5 PF09325.10 CEP10021.1 - 0.0026 17.3 3.4 0.0026 17.3 3.4 2.5 3 1 0 3 3 3 1 Vps5 C terminal like Holin_BhlA PF10960.8 CEP10021.1 - 0.004 17.1 16.4 2.7 8.0 0.4 4.8 4 1 0 4 4 4 2 BhlA holin family Prp18 PF02840.15 CEP10021.1 - 0.31 11.1 3.7 0.52 10.3 1.4 2.4 2 0 0 2 2 2 0 Prp18 domain Orthopox_F14 PF06076.12 CEP10021.1 - 0.69 10.2 5.5 6 7.2 0.1 3.3 2 1 1 3 3 3 0 Orthopoxvirus F14 protein HTH_OrfB_IS605 PF12323.8 CEP10021.1 - 6.2 6.4 6.0 7.1 6.2 1.7 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain CheY-binding PF09078.11 CEP10022.1 - 0.041 14.0 0.1 0.065 13.4 0.1 1.3 1 0 0 1 1 1 0 CheY binding COX14 PF14880.6 CEP10022.1 - 0.067 13.0 1.7 0.093 12.6 1.7 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Snf7 PF03357.21 CEP10023.1 - 4.1e-44 150.2 16.9 4.1e-44 150.2 16.9 1.7 1 1 1 2 2 2 1 Snf7 TraC PF07820.12 CEP10023.1 - 0.025 14.9 0.1 0.025 14.9 0.1 2.3 2 1 0 2 2 2 0 TraC-like protein DUF974 PF06159.13 CEP10023.1 - 0.043 13.6 0.4 0.057 13.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF974) DUF4442 PF14539.6 CEP10024.1 - 2.2e-15 57.0 0.0 1.6e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4442) MTA_R1 PF17226.2 CEP10024.1 - 0.018 15.2 0.4 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 MTA R1 domain KHA PF11834.8 CEP10026.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Cyt-b5 PF00173.28 CEP10027.1 - 2.7e-19 69.1 0.0 4.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pribosyl_synth PF14572.6 CEP10028.1 - 2.6e-47 161.2 3.3 8e-38 130.3 1.9 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CEP10028.1 - 4.9e-47 158.7 0.5 4.6e-46 155.5 0.1 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CEP10028.1 - 9.3e-14 51.2 3.6 9.9e-14 51.2 1.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Proteasome PF00227.26 CEP10029.1 - 1.1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4174 PF13778.6 CEP10029.1 - 0.031 14.8 0.1 0.63 10.5 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) Abhydrolase_2 PF02230.16 CEP10030.1 - 2.6e-65 220.3 0.0 3.1e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CEP10030.1 - 5.1e-11 42.3 0.0 1.6e-06 27.5 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CEP10030.1 - 7.1e-08 32.4 0.0 2.6e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CEP10030.1 - 1.1e-06 28.3 0.1 2.1e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 CEP10030.1 - 3.2e-06 26.9 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CEP10030.1 - 0.00017 22.3 0.0 0.00083 20.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CEP10030.1 - 0.0006 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 CEP10030.1 - 0.0013 18.2 0.0 0.23 10.9 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 CEP10030.1 - 0.0051 16.7 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CEP10030.1 - 0.0091 15.7 0.1 0.56 9.8 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 CEP10030.1 - 0.02 14.5 0.0 0.035 13.8 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 CEP10030.1 - 0.03 14.2 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF2920 PF11144.8 CEP10030.1 - 0.048 12.8 0.0 0.3 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Cutinase PF01083.22 CEP10030.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Cutinase Cuticle_3 PF11018.8 CEP10031.1 - 0.042 14.1 0.7 0.048 13.9 0.7 1.1 1 0 0 1 1 1 0 Pupal cuticle protein C1 PXPV PF12778.7 CEP10031.1 - 0.71 9.8 6.2 3 7.8 1.1 2.3 2 0 0 2 2 2 0 PXPV repeat (3 copies) Ric8 PF10165.9 CEP10032.1 - 8.9e-105 351.4 0.1 1.1e-104 351.1 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn FANCF PF11107.8 CEP10032.1 - 0.14 11.4 2.1 0.45 9.7 2.1 1.9 1 1 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Orbi_VP5 PF00901.17 CEP10033.1 - 9.9 4.4 12.4 0.24 9.8 1.2 2.5 3 0 0 3 3 3 0 Orbivirus outer capsid protein VP5 ABC_membrane PF00664.23 CEP10034.1 - 4.7e-70 236.4 36.4 4e-43 148.0 8.5 3.6 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CEP10034.1 - 2e-52 177.4 0.4 3.4e-29 102.1 0.0 3.2 4 0 0 4 4 2 2 ABC transporter SMC_N PF02463.19 CEP10034.1 - 7e-11 42.0 0.0 6.9e-05 22.4 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CEP10034.1 - 1.6e-05 25.0 3.8 0.038 14.1 0.5 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP10034.1 - 0.00019 21.4 0.2 0.08 12.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEP10034.1 - 0.00035 21.0 0.3 0.31 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEP10034.1 - 0.00036 20.2 1.3 0.095 12.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CEP10034.1 - 0.0018 18.4 5.4 0.61 10.1 0.4 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain NB-ARC PF00931.22 CEP10034.1 - 0.0036 16.5 0.4 0.38 9.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain RNase_3_N PF18497.1 CEP10034.1 - 0.0039 17.4 0.1 4.4 7.6 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease III N-terminal domain AAA_23 PF13476.6 CEP10034.1 - 0.017 15.6 0.1 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEP10034.1 - 0.027 13.5 0.0 6.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 CEP10034.1 - 0.06 13.6 0.1 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CEP10034.1 - 0.099 12.4 0.2 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 CEP10034.1 - 0.12 12.4 6.4 0.12 12.4 1.1 2.6 2 0 0 2 2 2 0 Dynamin family DnaB_C PF03796.15 CEP10034.1 - 0.13 11.6 0.1 0.8 9.0 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CEP10034.1 - 0.13 11.9 0.1 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEP10034.1 - 0.15 12.4 4.5 1.6 9.0 0.3 3.1 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CEP10034.1 - 0.17 11.7 1.1 17 5.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AIG1 PF04548.16 CEP10034.1 - 0.35 10.2 4.1 1.6 8.0 0.7 2.6 2 0 0 2 2 2 0 AIG1 family Ccdc124 PF06244.12 CEP10035.1 - 2.2e-15 57.3 29.9 2.2e-15 57.3 29.9 3.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Malate_synthase PF01274.22 CEP10036.1 - 2.2e-225 748.9 0.0 2.8e-225 748.5 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Glyco_transf_49 PF13896.6 CEP10036.1 - 1.8e-57 195.2 1.8 7.2e-43 147.2 0.3 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.9 CEP10036.1 - 0.027 13.9 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CEP10036.1 - 0.036 14.6 0.9 0.12 12.9 0.9 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Pyrophosphatase PF00719.19 CEP10037.1 - 1.1e-51 174.8 0.5 2.7e-51 173.5 0.5 1.7 1 0 0 1 1 1 1 Inorganic pyrophosphatase TPR_1 PF00515.28 CEP10037.1 - 4.1e-10 39.0 8.3 6.6e-07 28.9 0.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP10037.1 - 1.5e-09 37.3 3.3 0.00015 21.6 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP10037.1 - 3.2e-06 27.3 0.1 7.1e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP10037.1 - 2.9e-05 23.9 3.2 0.05 13.8 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP10037.1 - 7.1e-05 22.6 0.2 0.046 13.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10037.1 - 0.00011 21.8 5.3 0.011 15.4 0.1 3.2 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 CEP10037.1 - 0.00022 21.8 1.2 0.12 13.3 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP10037.1 - 0.00045 20.7 1.0 0.0013 19.2 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP10037.1 - 0.0056 16.8 0.6 0.18 11.9 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP10037.1 - 0.014 15.5 3.1 0.043 13.9 0.2 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CEP10037.1 - 0.05 14.3 1.6 0.34 11.6 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP10037.1 - 0.083 13.1 1.9 0.19 12.0 1.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PMC2NT PF08066.12 CEP10037.1 - 0.099 13.3 0.9 0.8 10.4 0.1 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain TPR_6 PF13174.6 CEP10037.1 - 1.2 9.9 4.5 37 5.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 CEP10038.1 - 9.8e-22 76.5 11.2 1.8e-21 75.7 11.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CEP10038.1 - 6e-07 29.2 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CEP10038.1 - 1.1e-06 28.4 8.6 2e-06 27.6 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP10038.1 - 0.00054 19.8 9.7 0.033 14.1 9.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CEP10038.1 - 0.0019 18.5 12.1 0.0036 17.6 12.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP10038.1 - 0.085 12.7 11.2 0.17 11.8 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CEP10038.1 - 0.28 11.3 3.0 0.75 9.9 3.0 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 CEP10038.1 - 0.54 10.2 11.2 1 9.3 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP10038.1 - 0.63 10.1 6.4 1.3 9.1 5.4 2.1 1 1 1 2 2 2 0 RING-type zinc-finger YpjP PF14005.6 CEP10039.1 - 0.035 14.2 0.4 0.038 14.0 0.4 1.1 1 0 0 1 1 1 0 YpjP-like protein P35 PF02331.15 CEP10039.1 - 0.075 12.4 0.1 0.08 12.3 0.1 1.0 1 0 0 1 1 1 0 Apoptosis preventing protein HJURP_C PF12347.8 CEP10040.1 - 0.0067 16.4 0.5 0.067 13.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction regulator protein family C-terminal repeat Herpes_gI PF01688.17 CEP10040.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I TANGO2 PF05742.12 CEP10041.1 - 2.1e-64 218.0 0.0 5.3e-64 216.7 0.0 1.6 2 0 0 2 2 2 1 Transport and Golgi organisation 2 BAR PF03114.18 CEP10041.1 - 1.6e-48 165.4 0.3 2.5e-48 164.8 0.3 1.2 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CEP10041.1 - 2.8e-05 24.0 0.1 4.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 CEP10041.1 - 0.0097 15.5 1.8 0.052 13.1 1.8 2.0 1 1 0 1 1 1 1 Arfaptin-like domain FeoB_Cyto PF17910.1 CEP10041.1 - 0.087 13.4 3.1 1.4 9.5 0.4 3.3 3 0 0 3 3 3 0 FeoB cytosolic helical domain SHE3 PF17078.5 CEP10041.1 - 0.12 12.1 2.8 6.1 6.5 0.3 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Occludin_ELL PF07303.13 CEP10041.1 - 0.73 10.6 3.8 2.9 8.7 0.2 3.2 3 0 0 3 3 3 0 Occludin homology domain Arb1 PF09692.10 CEP10042.1 - 6.4e-53 180.4 2.0 1.6e-43 149.4 0.3 2.2 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF2543 PF10820.8 CEP10042.1 - 0.13 12.5 1.7 3.4 7.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) MBOAT_2 PF13813.6 CEP10043.1 - 2.3e-11 43.8 0.2 5e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family UCH_1 PF13423.6 CEP10044.1 - 1.9e-10 40.9 0.0 0.002 17.8 0.1 3.3 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Zip PF02535.22 CEP10044.1 - 2.8 7.1 14.8 4.4 6.4 14.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 CEP10044.1 - 6.3 6.1 23.0 11 5.3 23.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Na_H_Exchanger PF00999.21 CEP10045.1 - 9.7e-60 202.3 26.2 1.3e-59 201.9 26.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 CEP10045.1 - 0.24 10.3 16.0 0.037 12.9 6.5 2.5 1 1 1 2 2 2 0 Carbon starvation protein CstA 60KD_IMP PF02096.20 CEP10045.1 - 1.3 8.9 6.9 5.9 6.8 3.3 3.1 3 0 0 3 3 3 0 60Kd inner membrane protein Phage_holin_3_3 PF16083.5 CEP10045.1 - 2.4 8.3 12.8 0.62 10.2 0.4 3.5 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III TFIIA PF03153.13 CEP10047.1 - 0.015 15.3 18.2 0.02 14.9 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.16 CEP10047.1 - 0.12 11.2 2.8 0.16 10.9 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Roughex PF06020.11 CEP10047.1 - 2.2 7.3 5.3 3.6 6.6 5.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SNAP PF14938.6 CEP10048.1 - 2.1e-96 322.7 14.7 2.4e-96 322.5 14.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CEP10048.1 - 0.00071 19.8 12.9 0.033 14.5 1.7 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP10048.1 - 0.0057 16.6 9.0 3.1 8.0 0.6 5.3 3 2 1 4 4 4 2 Tetratricopeptide repeat NSF PF02071.20 CEP10048.1 - 0.022 15.4 18.9 0.17 12.7 0.1 6.6 6 2 2 8 8 7 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 CEP10048.1 - 0.11 12.3 17.9 2 8.4 0.7 5.9 5 2 1 6 6 6 0 Tetratricopeptide repeat XPB_DRD PF18458.1 CEP10048.1 - 0.12 12.3 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain DUF4368 PF14287.6 CEP10048.1 - 0.18 12.2 0.1 83 3.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4368) Spatacsin_C PF14649.6 CEP10048.1 - 0.23 10.6 3.8 0.74 8.9 0.2 2.3 2 0 0 2 2 2 0 Spatacsin C-terminus MIT PF04212.18 CEP10048.1 - 1.5 8.9 19.3 0.85 9.7 1.7 4.9 4 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CEP10048.1 - 1.5 9.1 29.9 8.5 6.8 0.9 7.5 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEP10048.1 - 6.8 7.8 12.8 29 5.8 0.4 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 CEP10049.1 - 1.8e-32 112.8 0.2 8.4e-23 81.1 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10049.1 - 1.2e-14 54.2 0.1 2.3e-09 37.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEP10049.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med12 PF09497.10 CEP10050.1 - 1.9e-25 88.9 0.0 5.8e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 CEP10050.1 - 3.3e-09 36.1 0.6 3.5e-07 29.5 0.6 2.3 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain zf-C2H2 PF00096.26 CEP10051.1 - 7.8e-07 29.2 7.5 0.0026 18.1 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP10051.1 - 1.3e-05 25.6 6.6 0.035 14.9 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP10051.1 - 0.0033 18.0 1.7 0.37 11.4 0.2 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEP10051.1 - 0.017 15.4 2.4 0.37 11.1 2.6 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CEP10051.1 - 0.092 12.8 5.6 0.73 9.9 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CEP10051.1 - 0.18 11.5 1.2 0.34 10.6 1.2 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CEP10051.1 - 0.95 10.0 3.7 6.8 7.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain TT_ORF2 PF02957.15 CEP10051.1 - 4.1 8.4 7.5 37 5.3 0.1 2.5 2 0 0 2 2 2 0 TT viral ORF2 Lipase_3 PF01764.25 CEP10053.1 - 1.2e-07 31.6 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CEP10053.1 - 0.0062 15.8 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP10053.1 - 0.009 16.6 0.2 0.0098 16.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CEP10053.1 - 0.041 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Tctex-1 PF03645.13 CEP10053.1 - 0.043 14.1 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Tctex-1 family Abhydrolase_5 PF12695.7 CEP10053.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pex14_N PF04695.13 CEP10054.1 - 1.9 9.1 17.9 3.7 8.2 3.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.17 CEP10054.1 - 7.8 6.5 23.6 0.2 11.7 15.1 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4687 PF15747.5 CEP10055.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) RQC PF09382.10 CEP10056.1 - 1.9e-21 76.0 0.1 4.8e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 CEP10056.1 - 3.4e-20 72.5 0.0 1.1e-19 70.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP10056.1 - 1.1e-18 67.5 0.0 9.9e-17 61.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CEP10056.1 - 2.3e-17 63.5 5.2 8.2e-17 61.7 5.2 2.1 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 CEP10056.1 - 2.7e-10 40.1 0.1 9.3e-10 38.4 0.1 1.9 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 CEP10056.1 - 4.8e-06 26.7 0.0 1.7e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_Sgs1 PF11408.8 CEP10056.1 - 0.029 14.4 0.1 0.08 13.0 0.1 1.8 1 0 0 1 1 1 0 Sgs1 RecQ helicase Seryl_tRNA_N PF02403.22 CEP10056.1 - 0.28 11.4 8.4 0.047 13.9 1.8 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RRM_1 PF00076.22 CEP10058.1 - 1.7e-17 63.0 0.0 2.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OrfB_Zn_ribbon PF07282.11 CEP10059.1 - 1.8e-07 31.0 0.5 4.8e-07 29.6 0.5 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PIP5K PF01504.18 CEP10059.1 - 0.00074 18.8 1.9 0.0011 18.3 1.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Spore_coat_CotO PF14153.6 CEP10059.1 - 0.0031 17.5 1.9 0.0039 17.2 1.9 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Elf1 PF05129.13 CEP10059.1 - 0.024 14.7 2.3 0.024 14.7 2.3 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Usp PF00582.26 CEP10059.1 - 0.14 12.6 0.1 0.21 12.1 0.1 1.2 1 0 0 1 1 1 0 Universal stress protein family DUF3304 PF11745.8 CEP10059.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) IBR PF01485.21 CEP10060.1 - 0.02 15.1 6.7 0.4 10.9 0.7 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-CCHC_3 PF13917.6 CEP10060.1 - 0.033 14.2 0.4 0.033 14.2 0.4 2.7 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP10060.1 - 0.069 13.3 9.7 0.6 10.3 0.3 3.0 3 0 0 3 3 3 0 Zinc knuckle ZZ PF00569.17 CEP10060.1 - 0.64 9.9 7.5 0.26 11.1 1.3 2.8 2 1 0 2 2 2 0 Zinc finger, ZZ type COX17 PF05051.13 CEP10061.1 - 7.5e-21 74.2 4.8 1.2e-20 73.5 4.8 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) YL1 PF05764.13 CEP10061.1 - 1.2 9.3 6.3 1.7 8.7 6.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L32p PF01783.23 CEP10062.1 - 1.3e-15 57.3 4.8 2e-15 56.8 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc_ribbon_2 PF13240.6 CEP10062.1 - 0.0068 16.1 2.4 0.036 13.8 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEP10062.1 - 0.039 13.9 0.6 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbons Zn-ribbon_8 PF09723.10 CEP10062.1 - 0.53 10.5 2.3 0.66 10.1 0.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 CEP10062.1 - 1.3 8.5 5.0 0.65 9.5 0.8 1.6 1 1 1 2 2 2 0 zinc-ribbon domain IF-2B PF01008.17 CEP10063.1 - 3.6e-80 269.2 0.0 5.9e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ndc1_Nup PF09531.10 CEP10063.1 - 0.65 8.6 3.1 0.89 8.2 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 CEP10063.1 - 1.9 6.9 8.7 2.4 6.6 8.7 1.1 1 0 0 1 1 1 0 Macoilin family PMT_4TMC PF16192.5 CEP10064.1 - 7.8e-63 211.7 6.6 1.8e-62 210.5 6.6 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 CEP10064.1 - 1.7e-56 191.6 16.6 6.9e-39 133.9 11.7 2.4 1 1 1 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CEP10064.1 - 1.2e-34 119.8 1.2 3e-34 118.5 0.8 1.8 1 1 1 2 2 2 1 MIR domain Ins145_P3_rec PF08709.11 CEP10064.1 - 0.033 13.4 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Frizzled PF01534.17 CEP10065.1 - 5.5e-07 28.9 15.6 1e-06 28.1 15.6 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CEP10065.1 - 2.7e-05 24.8 6.1 5.1e-05 23.9 6.1 1.5 1 0 0 1 1 1 1 Fz domain Strabismus PF06638.11 CEP10065.1 - 0.12 11.0 0.5 0.23 10.1 0.5 1.4 1 0 0 1 1 1 0 Strabismus protein PspB PF06667.12 CEP10065.1 - 1.5 8.9 4.2 2.4 8.3 0.6 3.0 3 0 0 3 3 3 0 Phage shock protein B TMEM208_SND2 PF05620.11 CEP10065.1 - 3.9 7.2 8.3 6.6 6.5 0.4 3.4 2 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 PGG PF13962.6 CEP10065.1 - 8 6.3 11.5 0.067 13.0 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function LIAS_N PF16881.5 CEP10066.1 - 1.4e-21 76.9 0.4 2.9e-21 75.9 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CEP10066.1 - 8e-11 42.6 0.4 1.5e-10 41.7 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Lactamase_B PF00753.27 CEP10067.1 - 1.4e-18 67.6 0.5 2.7e-18 66.7 0.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP10067.1 - 0.00018 21.1 0.1 0.00039 20.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 CEP10067.1 - 0.00044 20.2 0.2 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_6 PF16661.5 CEP10067.1 - 0.0047 16.4 0.3 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP10067.1 - 0.095 12.6 0.5 0.19 11.6 0.2 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain COG5 PF10392.9 CEP10068.1 - 0.059 13.5 1.3 0.13 12.4 1.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 PDDEXK_6 PF04720.12 CEP10068.1 - 1.9 8.4 6.3 0.15 12.0 0.5 2.0 2 0 0 2 2 2 0 PDDEXK-like family of unknown function PIG-P PF08510.12 CEP10069.1 - 8.8e-39 132.2 7.3 8.8e-39 132.2 7.3 1.5 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 CEP10069.1 - 0.23 11.8 8.3 0.44 10.9 8.3 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Gln-synt_C PF00120.24 CEP10070.1 - 1.5e-21 76.8 0.0 7.7e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CEP10070.1 - 1.1e-11 44.3 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DDE_3 PF13358.6 CEP10071.1 - 1.1e-05 25.3 0.0 2.8e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP10071.1 - 0.00017 22.2 0.0 0.0004 21.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CEP10071.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_psq PF05225.16 CEP10071.1 - 0.0044 16.7 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_7 PF02796.15 CEP10071.1 - 0.014 15.5 0.0 7 6.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP10071.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MerR_1 PF13411.6 CEP10071.1 - 0.12 12.5 0.3 2.8 8.1 0.1 2.7 1 1 1 2 2 2 0 MerR HTH family regulatory protein DNA_pol_lambd_f PF10391.9 CEP10071.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HTH_28 PF13518.6 CEP10071.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Reticulon PF02453.17 CEP10072.1 - 2.8e-22 79.4 4.3 4.6e-22 78.7 4.3 1.3 1 0 0 1 1 1 1 Reticulon ApoO PF09769.9 CEP10072.1 - 7.5 6.5 6.7 5.1 7.1 0.7 2.5 2 0 0 2 2 2 0 Apolipoprotein O UPF0203 PF05254.12 CEP10073.1 - 1.2e-18 67.1 5.7 2.6e-18 66.0 5.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 CEP10073.1 - 0.031 14.6 0.8 0.081 13.3 0.8 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 CEP10073.1 - 0.053 13.7 0.9 0.14 12.4 0.9 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein RNA_pol_3_Rpc31 PF11705.8 CEP10073.1 - 0.5 10.6 6.4 0.83 9.9 6.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cmc1 PF08583.10 CEP10073.1 - 2.1 8.5 5.9 1e+02 3.0 7.0 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF397 PF04149.12 CEP10075.1 - 0.029 14.4 0.2 0.052 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF397) LSM PF01423.22 CEP10076.1 - 2.3e-21 75.3 0.0 2.7e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEP10076.1 - 0.0054 16.8 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Nbas_N PF15492.6 CEP10076.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Zn_clus PF00172.18 CEP10077.1 - 6.3e-05 23.0 13.4 0.00012 22.1 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain vATP-synt_E PF01991.18 CEP10077.1 - 2.3 7.6 5.2 0.45 9.9 1.6 1.6 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit BAR_3 PF16746.5 CEP10078.1 - 1.4e-54 185.3 6.8 3e-54 184.2 6.8 1.5 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 CEP10078.1 - 5.9e-38 129.5 0.0 5.9e-38 129.5 0.0 2.8 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 CEP10078.1 - 1.2e-18 67.5 5.3 7.1e-11 42.6 0.8 2.5 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP10078.1 - 2.9e-14 53.2 0.4 5.6e-11 42.7 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 CEP10078.1 - 1.8e-13 50.9 0.1 5.5e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 PH domain BAR PF03114.18 CEP10078.1 - 4.3e-12 46.2 4.7 8.6e-12 45.2 4.7 1.5 1 0 0 1 1 1 1 BAR domain Ank_5 PF13857.6 CEP10078.1 - 3.3e-10 40.0 2.9 1e-05 25.7 1.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP10078.1 - 3.1e-08 33.2 0.1 0.00016 21.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEP10078.1 - 1.7e-06 28.2 0.1 0.0012 19.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Arfaptin PF06456.13 CEP10078.1 - 0.0039 16.8 4.5 0.01 15.4 4.5 1.7 1 0 0 1 1 1 1 Arfaptin-like domain zf-B_box PF00643.24 CEP10078.1 - 0.0066 16.6 0.2 0.015 15.4 0.2 1.6 1 0 0 1 1 1 1 B-box zinc finger PH_13 PF16652.5 CEP10078.1 - 0.019 14.8 0.7 0.046 13.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF5327 PF17261.2 CEP10078.1 - 0.18 12.6 6.8 0.093 13.5 1.6 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5327) E1_dh PF00676.20 CEP10079.1 - 4.1e-96 321.5 0.2 5e-96 321.2 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CEP10079.1 - 0.0025 17.6 0.1 0.016 15.0 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CEP10079.1 - 0.0079 15.4 0.0 0.03 13.5 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Med21 PF11221.8 CEP10079.1 - 0.067 13.4 1.1 0.1 12.8 0.2 1.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex AMMECR1 PF01871.17 CEP10080.1 - 1.6e-46 158.0 0.0 1.8e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 BSD PF03909.17 CEP10081.1 - 1.4e-17 63.4 1.5 4.2e-17 61.9 0.5 2.4 2 0 0 2 2 2 1 BSD domain Prominin PF05478.11 CEP10081.1 - 0.12 10.3 0.9 0.18 9.7 0.9 1.2 1 0 0 1 1 1 0 Prominin Catalase PF00199.19 CEP10083.1 - 1.3e-198 659.8 0.5 1.6e-198 659.5 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEP10083.1 - 3.3e-20 72.1 0.1 6.9e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive WD40 PF00400.32 CEP10084.1 - 1.3e-41 139.8 20.5 5e-07 30.3 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP10084.1 - 2.9e-11 43.5 3.0 0.063 13.6 0.1 5.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP10084.1 - 1e-09 38.1 1.4 2e-09 37.2 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP10084.1 - 2.1e-09 37.0 1.2 4.3e-09 36.0 1.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CEP10084.1 - 7.4e-08 31.5 3.5 0.38 9.3 0.1 5.6 2 2 4 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 CEP10084.1 - 1.5e-05 24.9 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box PALB2_WD40 PF16756.5 CEP10084.1 - 0.00095 18.2 0.2 6.1 5.7 0.0 3.8 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 CEP10084.1 - 0.0093 16.4 0.0 5.3 7.7 0.0 3.1 2 0 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 CEP10084.1 - 0.016 14.6 0.1 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain DUF5046 PF16465.5 CEP10084.1 - 0.096 12.1 0.0 21 4.5 0.0 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 CEP10084.1 - 0.11 12.1 1.3 4.1 6.9 1.2 2.9 1 1 0 1 1 1 0 PQQ-like domain Kelch_6 PF13964.6 CEP10084.1 - 0.29 11.5 1.2 21 5.6 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Pkinase PF00069.25 CEP10085.1 - 1.1e-69 234.8 0.0 1.3e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10085.1 - 2.1e-41 142.0 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP10085.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEP10085.1 - 0.013 15.1 0.5 0.02 14.5 0.0 1.5 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CEP10085.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP10085.1 - 0.03 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Nop14 PF04147.12 CEP10086.1 - 4e-05 22.1 14.6 4e-05 22.1 14.6 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CEP10086.1 - 0.0004 19.9 16.3 0.00047 19.7 16.3 1.1 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 CEP10086.1 - 0.0004 19.0 10.1 0.0004 19.0 10.1 1.1 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 CEP10086.1 - 0.0019 16.6 11.4 0.0019 16.6 11.4 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 CEP10086.1 - 0.0033 16.8 12.4 0.0033 16.8 12.4 1.1 1 0 0 1 1 1 1 BUD22 DUF2457 PF10446.9 CEP10086.1 - 0.0057 15.9 30.3 0.008 15.4 30.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RPN2_C PF18004.1 CEP10086.1 - 0.012 15.6 2.9 0.02 14.8 2.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain YL1 PF05764.13 CEP10086.1 - 0.014 15.5 16.3 0.016 15.3 16.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Afi1 PF07792.12 CEP10086.1 - 0.025 15.1 6.8 0.04 14.4 6.8 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CobT PF06213.12 CEP10086.1 - 0.025 14.0 15.0 0.031 13.7 15.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.11 CEP10086.1 - 0.034 13.8 17.1 0.062 12.9 17.1 1.5 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 CEP10086.1 - 0.1 11.4 3.4 0.095 11.5 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 CEP10086.1 - 0.22 10.6 8.4 0.21 10.6 8.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 CEP10086.1 - 0.23 10.4 1.9 0.27 10.2 1.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 CEP10086.1 - 0.45 10.8 7.6 0.68 10.2 7.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.13 CEP10086.1 - 0.47 10.3 19.0 0.71 9.7 19.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 CEP10086.1 - 0.66 8.0 37.7 0.89 7.6 37.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 CEP10086.1 - 0.83 9.4 11.0 1.1 9.0 11.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2722 PF10846.8 CEP10086.1 - 0.87 8.5 10.3 0.97 8.3 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4811 PF16069.5 CEP10086.1 - 0.96 9.3 6.1 1.9 8.3 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) Rhabdo_ncap PF00945.18 CEP10086.1 - 1.8 7.4 8.4 2.3 7.0 8.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2076 PF09849.9 CEP10086.1 - 2 8.4 18.6 2.7 8.0 18.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4637 PF15470.6 CEP10086.1 - 2 8.1 10.3 3.5 7.3 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) IFT57 PF10498.9 CEP10086.1 - 4.2 6.2 8.9 4.9 6.0 8.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 COPI_C PF06957.11 CEP10086.1 - 8.4 5.0 11.6 10 4.7 11.6 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ERG4_ERG24 PF01222.17 CEP10087.1 - 1.4e-142 475.5 21.3 1.6e-142 475.3 21.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 CEP10087.1 - 0.036 14.5 0.5 0.036 14.5 0.5 3.1 2 1 0 2 2 2 0 Phospholipid methyltransferase R3H-assoc PF13902.6 CEP10088.1 - 0.00051 20.4 0.2 0.0033 17.8 0.0 2.1 2 0 0 2 2 2 1 R3H-associated N-terminal domain Abhydrolase_1 PF00561.20 CEP10089.1 - 8.4e-05 22.3 1.2 0.0003 20.5 0.5 2.2 2 2 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP10089.1 - 0.11 11.7 0.2 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Exo84_C PF16528.5 CEP10090.1 - 1.3e-48 165.6 3.6 2.7e-48 164.5 3.6 1.6 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CEP10090.1 - 1.9e-13 50.3 0.1 1.8e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 CEP10090.1 - 0.0012 18.9 0.8 0.0032 17.5 0.2 2.0 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 CEP10090.1 - 0.023 14.5 0.6 0.023 14.5 0.6 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 Lin-8 PF03353.15 CEP10090.1 - 0.065 12.8 0.3 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist KaiA PF07688.12 CEP10090.1 - 0.17 12.0 3.5 1.5 9.0 0.3 2.7 2 0 0 2 2 2 0 KaiA C-terminal domain AMP-binding PF00501.28 CEP10091.1 - 9.6e-90 301.2 0.0 1.4e-89 300.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP10091.1 - 0.0039 18.1 0.0 0.0081 17.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3783 PF12646.7 CEP10091.1 - 0.026 14.5 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Zip PF02535.22 CEP10092.1 - 5.2e-55 187.0 9.7 5.2e-55 187.0 9.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Aconitase_C PF00694.19 CEP10092.1 - 0.0075 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Arch_flagellin PF01917.16 CEP10092.1 - 0.022 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Archaebacterial flagellin Mntp PF02659.15 CEP10092.1 - 1.3 8.8 9.4 1.4 8.7 0.5 3.1 2 1 1 3 3 3 0 Putative manganese efflux pump FCH PF00611.23 CEP10093.1 - 1.4e-07 31.7 0.4 1.4e-07 31.7 0.4 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CEP10093.1 - 0.038 13.6 0.1 0.076 12.6 0.1 1.5 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 CEP10093.1 - 0.069 13.0 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain HTHP PF11534.8 CEP10093.1 - 0.099 13.1 0.2 0.5 10.8 0.2 2.2 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) SH3_2 PF07653.17 CEP10093.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DUF2852 PF11014.8 CEP10093.1 - 3.3 7.9 13.6 0.052 13.7 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SMC_N PF02463.19 CEP10094.1 - 1.2e-63 214.6 54.6 1e-61 208.2 54.6 4.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEP10094.1 - 1.4e-24 86.6 0.2 5.4e-24 84.7 0.2 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CEP10094.1 - 1.2e-11 45.0 17.0 1.2e-11 45.0 17.0 4.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CEP10094.1 - 4.5e-08 33.3 23.5 4.5e-07 30.0 0.1 4.1 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEP10094.1 - 2.7e-06 27.0 0.0 9.7e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CEP10094.1 - 0.0032 18.0 43.5 0.0032 18.0 43.5 7.3 2 2 3 5 5 5 1 AAA domain ABC_tran PF00005.27 CEP10094.1 - 0.094 13.2 0.0 0.094 13.2 0.0 6.5 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.6 CEP10094.1 - 0.14 10.8 103.7 0.16 10.6 21.6 4.7 3 2 2 5 5 5 0 AAA domain Herpes_TK_C PF08465.10 CEP10095.1 - 0.086 12.6 0.2 0.32 10.8 0.2 1.9 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal HisKA_2 PF07568.12 CEP10095.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase Ribosomal_L18A PF01775.17 CEP10097.1 - 1.1e-52 177.2 2.8 1.4e-52 176.9 2.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PLA2_B PF01735.18 CEP10098.1 - 2.9e-39 134.8 2.1 1.1e-18 66.9 0.0 2.8 3 0 0 3 3 3 2 Lysophospholipase catalytic domain GTP_CH_N PF12471.8 CEP10100.1 - 2.3e-91 304.8 0.0 3.2e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CEP10100.1 - 3.3e-15 56.0 0.0 4.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 CEP10100.1 - 0.15 11.7 0.0 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family UPRTase PF14681.6 CEP10101.1 - 3.8e-64 215.9 0.0 4.3e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CEP10101.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain HTH_Tnp_Tc3_2 PF01498.18 CEP10102.1 - 2.7e-09 37.2 0.9 5.6e-09 36.1 0.5 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 CEP10102.1 - 0.005 16.8 0.0 0.093 12.8 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP10102.1 - 0.013 15.3 0.0 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB THP2 PF09432.10 CEP10102.1 - 0.015 15.4 0.1 0.018 15.1 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 HTH_7 PF02796.15 CEP10102.1 - 0.04 14.0 1.8 1.1 9.3 0.1 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase MRP-L20 PF12824.7 CEP10103.1 - 7.3e-23 81.5 1.6 1.2e-22 80.8 1.6 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF1687 PF07955.11 CEP10103.1 - 0.00033 21.1 1.4 0.00065 20.2 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1687) ArsC PF03960.15 CEP10103.1 - 0.018 15.0 0.2 0.055 13.5 0.0 2.0 2 1 0 2 2 2 0 ArsC family HTH_32 PF13565.6 CEP10103.1 - 0.055 14.1 0.1 0.22 12.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Toprim_Crpt PF13342.6 CEP10103.1 - 1.3 9.0 4.4 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Adaptin_binding PF10199.9 CEP10104.1 - 1.9e-08 35.0 5.9 2.9e-08 34.4 5.9 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF2218 PF09981.9 CEP10105.1 - 0.16 12.4 0.0 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) SCAI PF12070.8 CEP10107.1 - 2e-189 630.9 1.8 1e-188 628.6 1.8 2.2 1 1 0 1 1 1 1 Protein SCAI UPF0715 PF17094.5 CEP10107.1 - 0.14 12.7 0.3 0.68 10.5 0.1 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0715) zf-Tim10_DDP PF02953.15 CEP10108.1 - 1.5e-19 69.4 1.9 1.5e-19 69.4 1.9 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 CEP10108.1 - 0.0026 18.0 0.1 0.071 13.4 0.0 2.0 1 1 0 2 2 2 1 Phasin protein DUF842 PF05811.13 CEP10108.1 - 0.021 14.5 2.3 0.054 13.2 2.2 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FH2 PF02181.23 CEP10109.1 - 9.4e-80 268.5 16.4 9.4e-80 268.5 16.4 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CEP10109.1 - 3.2e-29 102.0 3.3 4.5e-27 94.9 0.1 2.9 2 0 0 2 2 2 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CEP10109.1 - 3e-14 53.0 2.0 1e-09 38.2 0.0 3.5 2 1 1 3 3 3 2 Diaphanous GTPase-binding Domain zf-RING_11 PF17123.5 CEP10109.1 - 0.0025 17.5 0.3 0.0054 16.5 0.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger Fe_bilin_red PF05996.12 CEP10109.1 - 0.0027 17.4 4.9 0.006 16.3 4.9 1.5 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase zf-RING_UBOX PF13445.6 CEP10109.1 - 0.032 14.3 0.1 0.032 14.3 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CEP10109.1 - 0.043 14.1 0.4 0.085 13.2 0.4 1.5 1 0 0 1 1 1 0 Ring finger domain DUF3158 PF11358.8 CEP10109.1 - 0.05 13.3 1.3 0.89 9.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3158) zf-C3HC4 PF00097.25 CEP10109.1 - 0.1 12.5 0.8 0.22 11.4 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP10109.1 - 0.22 11.4 0.7 0.42 10.5 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NTP_transf_6 PF06042.11 CEP10109.1 - 0.27 11.1 3.9 0.49 10.2 0.3 2.9 3 0 0 3 3 3 0 Nucleotidyltransferase DNA_pack_N PF02500.15 CEP10109.1 - 1.3 8.8 7.4 0.081 12.7 0.5 2.5 2 1 1 3 3 3 0 Probable DNA packing protein, N-terminus DUF4093 PF13331.6 CEP10109.1 - 2.2 8.8 4.7 2.9 8.4 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) DUF1752 PF08550.10 CEP10110.1 - 3.1e-12 46.1 4.0 6.7e-12 45.0 4.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) JUPITER PF17054.5 CEP10112.1 - 1.8 8.0 9.2 0.056 12.9 2.0 1.9 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter T4SS_CagC PF16943.5 CEP10113.1 - 0.071 13.3 1.0 0.35 11.1 1.0 1.9 1 1 0 1 1 1 0 Cag pathogenicity island, type IV secretory system SSrecog PF03531.14 CEP10113.1 - 0.11 12.5 0.0 0.19 11.7 0.1 1.5 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) RdRP PF05183.12 CEP10114.1 - 4.1e-186 620.1 0.0 5.3e-186 619.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 CEP10114.1 - 2.8e-44 148.8 0.0 2.4e-15 56.1 0.0 6.1 7 0 0 7 7 7 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP10114.1 - 0.00046 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CEP10114.1 - 0.0012 18.5 0.0 0.0032 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP10114.1 - 0.0071 16.4 0.0 0.91 9.7 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CEP10114.1 - 0.01 15.8 0.1 0.053 13.5 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_3_Rpc31 PF11705.8 CEP10114.1 - 0.11 12.8 2.9 0.2 11.9 2.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PIF1 PF05970.14 CEP10115.1 - 7.1e-59 199.8 2.3 5.7e-48 163.9 0.1 3.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CEP10115.1 - 2e-25 89.6 0.0 3.3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP10115.1 - 9.5e-10 39.0 0.0 1.7e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CEP10115.1 - 4.9e-07 28.1 0.0 0.00016 19.8 0.0 2.3 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 CEP10115.1 - 3.1e-05 23.7 0.0 8.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CEP10115.1 - 0.00017 21.8 0.0 0.00052 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CEP10115.1 - 0.00026 20.6 0.2 0.00065 19.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 CEP10115.1 - 0.00043 20.7 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEP10115.1 - 0.0006 19.0 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CEP10115.1 - 0.0018 18.7 0.2 0.0058 17.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 CEP10115.1 - 0.0032 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Helicase NACHT PF05729.12 CEP10115.1 - 0.0037 17.2 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 CEP10115.1 - 0.016 15.0 0.1 3.7 7.2 0.1 3.2 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 CEP10115.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 CEP10115.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 CEP10115.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 CEP10115.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 CEP10115.1 - 0.031 13.7 0.0 0.12 11.8 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein MMR_HSR1 PF01926.23 CEP10115.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CEP10115.1 - 0.065 13.7 0.0 0.065 13.7 0.0 2.4 3 1 0 3 3 1 0 ABC transporter NTPase_1 PF03266.15 CEP10115.1 - 0.076 12.9 0.1 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_14 PF13173.6 CEP10115.1 - 0.081 13.0 0.0 0.44 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEP10115.1 - 0.084 12.9 0.2 0.44 10.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEP10115.1 - 0.11 12.9 0.4 0.62 10.5 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_29 PF13555.6 CEP10115.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 1 0 P-loop containing region of AAA domain Zn_clus PF00172.18 CEP10116.1 - 3e-10 40.1 8.0 5.7e-10 39.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRCR_2 PF15494.6 CEP10117.1 - 0.088 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DiS_P_DiS PF06750.13 CEP10117.1 - 0.093 12.9 0.4 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain NDC10_II PF16787.5 CEP10118.1 - 1e-13 51.1 0.1 1.8e-13 50.3 0.1 1.4 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Kinesin PF00225.23 CEP10119.1 - 0.00032 19.7 0.3 0.00053 19.0 0.3 1.4 1 1 0 1 1 1 1 Kinesin motor domain DUF3391 PF11871.8 CEP10120.1 - 0.57 10.7 7.9 0.71 10.4 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DcuC PF03606.15 CEP10120.1 - 0.63 8.4 1.2 0.69 8.3 1.2 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DNA_pol_phi PF04931.13 CEP10120.1 - 2.6 6.1 36.6 2.7 6.0 36.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Trypan_PARP PF05887.11 CEP10120.1 - 6.8 6.7 15.7 7.2 6.6 15.7 1.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 CEP10120.1 - 6.9 4.7 28.7 6.5 4.8 28.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1980 PF09323.10 CEP10120.1 - 7.3 6.5 5.2 8 6.3 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Mak16 PF04874.14 CEP10120.1 - 9.2 6.9 23.2 11 6.7 23.2 1.1 1 0 0 1 1 1 0 Mak16 protein C-terminal region zf-CCHC PF00098.23 CEP10122.1 - 0.011 15.8 12.8 0.15 12.2 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP10122.1 - 0.018 14.8 4.1 0.018 14.8 4.1 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP10122.1 - 1.7 8.6 17.7 1.3 8.9 7.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP10122.1 - 4.4 7.1 7.1 4.4 7.1 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Helitron_like_N PF14214.6 CEP10123.1 - 7.3e-62 209.0 0.0 1.2e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SUIM_assoc PF16619.5 CEP10125.1 - 0.011 15.8 2.8 0.027 14.5 2.8 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CEP10125.1 - 1.8 8.5 7.5 2.9 7.8 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.26 CEP10126.1 - 2.4e-18 66.4 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP10126.1 - 4.9e-05 23.0 0.0 0.0003 20.5 0.0 2.3 1 1 1 2 2 2 1 Integrase core domain XRN1_D2_D3 PF18334.1 CEP10126.1 - 0.085 13.1 0.4 18 5.6 0.1 2.6 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain BTG PF07742.12 CEP10126.1 - 0.11 12.3 0.1 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 BTG family BILBO1_N PF18281.1 CEP10126.1 - 0.12 12.9 0.5 23 5.5 0.0 3.2 2 1 1 3 3 3 0 BILBO1 N-terminal domain RT_RNaseH_2 PF17919.1 CEP10129.1 - 9.5e-35 118.6 0.0 1.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10129.1 - 1.1e-32 112.5 0.0 1.7e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CEP10129.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 Pao retrotransposon peptidase RVT_1 PF00078.27 CEP10129.1 - 0.088 12.3 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2774 PF11242.8 CEP10129.1 - 0.23 11.7 0.4 38 4.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) NYAP_C PF15452.6 CEP10131.1 - 0.031 14.1 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF4199 PF13858.6 CEP10131.1 - 0.36 11.2 1.0 0.61 10.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RVT_1 PF00078.27 CEP10133.1 - 2.8e-17 63.0 0.4 4e-17 62.5 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP10134.1 - 5.9e-07 29.2 0.0 6.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP10136.1 - 3.4e-06 27.7 1.4 4e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase MLVIN_C PF18697.1 CEP10138.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain EPSP_synthase PF00275.20 CEP10139.1 - 4.3e-125 417.7 0.1 6.7e-125 417.1 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CEP10139.1 - 1e-92 310.0 0.2 2.3e-92 308.9 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CEP10139.1 - 2.6e-51 175.1 0.0 5e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CEP10139.1 - 1.7e-33 116.0 0.0 4.1e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 CEP10139.1 - 9e-24 83.6 0.1 2.8e-23 82.0 0.0 2.0 2 0 0 2 2 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CEP10139.1 - 2.9e-10 39.7 0.0 6.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CEP10139.1 - 9.5e-09 35.4 0.0 2.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 CEP10139.1 - 1.1e-05 25.3 0.0 4e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_18 PF13238.6 CEP10139.1 - 0.0059 17.2 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP10139.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP10139.1 - 0.019 15.1 0.0 0.11 12.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain YlzJ PF14035.6 CEP10139.1 - 0.058 13.6 0.1 3.8 7.8 0.1 2.7 2 0 0 2 2 2 0 YlzJ-like protein AAA_16 PF13191.6 CEP10139.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CEP10139.1 - 0.14 11.3 0.7 0.32 10.1 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain Fer4_24 PF18109.1 CEP10140.1 - 0.031 14.6 0.4 0.031 14.6 0.4 1.8 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Mit_KHE1 PF10173.9 CEP10140.1 - 0.68 10.0 8.7 1.1 9.3 1.7 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related L27_1 PF09058.10 CEP10142.1 - 0.027 14.4 1.6 1.2 9.1 1.6 2.8 1 1 0 1 1 1 0 L27_1 FlxA PF14282.6 CEP10142.1 - 0.46 10.5 7.9 0.55 10.2 4.3 2.2 2 0 0 2 2 2 0 FlxA-like protein NMT_C PF02799.15 CEP10143.1 - 0.063 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Na_Ca_ex PF01699.24 CEP10145.1 - 3.8e-44 150.3 41.4 3.1e-25 88.9 14.4 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3984 PF13136.6 CEP10146.1 - 1.4 8.3 4.9 1.8 7.9 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2457 PF10446.9 CEP10146.1 - 6.1 5.9 6.4 0.78 8.8 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) F-box PF00646.33 CEP10147.1 - 1.7e-05 24.6 0.0 4.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP10147.1 - 6e-05 22.9 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like Gly_transf_sug PF04488.15 CEP10148.1 - 1.2e-07 32.3 0.3 5.1e-07 30.2 0.1 2.1 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CEP10148.1 - 0.0067 15.8 0.5 0.015 14.7 0.5 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 CEP10148.1 - 0.061 12.6 0.2 0.1 11.9 0.2 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Pkinase PF00069.25 CEP10150.1 - 2.7e-62 210.5 0.0 3.6e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10150.1 - 6.4e-30 104.3 0.0 9.3e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP10150.1 - 2.5e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP10150.1 - 6e-05 22.0 0.1 0.00016 20.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEP10150.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.21 CEP10151.1 - 2.9e-35 120.8 0.0 4e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Cyclin_N PF00134.23 CEP10152.1 - 4e-14 52.5 0.4 1.1e-13 51.0 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mg_trans_NIPA PF05653.14 CEP10153.1 - 6.9e-20 71.3 16.1 3.4e-10 39.5 6.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CEP10153.1 - 0.0038 17.4 4.3 0.0038 17.4 4.3 3.2 3 1 0 3 3 3 2 EamA-like transporter family Trp_oprn_chp PF09534.10 CEP10153.1 - 0.062 13.1 0.6 5.7 6.7 0.0 3.2 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LapA_dom PF06305.11 CEP10153.1 - 0.23 11.3 11.6 0.54 10.1 0.6 4.5 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 CEP10153.1 - 0.9 10.5 0.0 0.9 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) RhoGAP PF00620.27 CEP10154.1 - 1e-41 142.3 0.4 4.4e-41 140.2 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CEP10154.1 - 8e-19 68.1 0.2 3.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 PH domain PX PF00787.24 CEP10154.1 - 2.1e-11 43.8 0.3 1.4e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 PX domain PH_11 PF15413.6 CEP10154.1 - 1.6e-08 34.9 0.2 1.6e-08 34.9 0.2 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 CEP10154.1 - 0.00013 22.1 0.1 0.00098 19.4 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain KASH_CCD PF14662.6 CEP10154.1 - 0.041 13.7 5.4 0.11 12.4 5.4 1.6 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMEM192 PF14802.6 CEP10154.1 - 5.2 6.1 8.6 0.43 9.6 2.2 2.1 2 0 0 2 2 2 0 TMEM192 family Spc7 PF08317.11 CEP10154.1 - 9.6 5.0 11.0 0.11 11.3 3.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Exo_endo_phos PF03372.23 CEP10155.1 - 8.6e-06 25.4 0.0 2.6e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 CEP10155.1 - 0.13 12.3 0.1 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_S21 PF01165.20 CEP10156.1 - 1.2e-12 47.3 3.9 1.9e-12 46.7 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 Exostosin PF03016.15 CEP10157.1 - 2.4e-39 135.4 0.5 2.9e-39 135.0 0.5 1.0 1 0 0 1 1 1 1 Exostosin family Glyco_transf_10 PF00852.19 CEP10157.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term HMG_box PF00505.19 CEP10159.1 - 2.4e-19 69.5 2.0 4.9e-19 68.5 2.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP10159.1 - 4.4e-07 30.4 0.6 1.1e-06 29.1 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain Chorion_2 PF03964.15 CEP10160.1 - 1.8 9.4 8.5 0.14 13.0 2.7 2.0 2 0 0 2 2 2 0 Chorion family 2 bZIP_1 PF00170.21 CEP10161.1 - 4.3e-12 45.9 7.5 4.3e-12 45.9 7.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP10161.1 - 3.9e-09 36.5 6.5 1.1e-08 35.0 6.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP10161.1 - 0.019 15.5 7.9 0.022 15.2 6.2 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor HALZ PF02183.18 CEP10161.1 - 0.077 13.2 0.7 0.16 12.2 0.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3128 PF11326.8 CEP10162.1 - 0.0059 16.9 1.9 0.0091 16.3 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) NDUF_B7 PF05676.13 CEP10162.1 - 0.013 15.2 4.3 0.013 15.2 4.3 2.0 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 CEP10162.1 - 0.022 15.0 1.7 0.022 15.0 1.7 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 CEP10162.1 - 0.034 14.2 5.5 0.061 13.3 5.5 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 CEP10162.1 - 0.092 13.0 4.3 0.16 12.2 4.3 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Adeno_PVIII PF01310.18 CEP10162.1 - 0.16 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Pet191_N PF10203.9 CEP10162.1 - 0.16 12.3 2.9 0.16 12.3 1.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 START PF01852.19 CEP10163.1 - 8.9e-21 74.3 0.2 1.5e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 START domain Glyco_hydro_5_C PF18564.1 CEP10163.1 - 0.00019 21.9 0.0 0.00075 20.0 0.0 2.1 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain SMYLE_N PF18615.1 CEP10163.1 - 0.0051 16.4 0.7 0.016 14.8 0.7 1.8 1 0 0 1 1 1 1 Short myomegalin-like EB1 binding proteins, N-terminal domain Mago_nashi PF02792.14 CEP10164.1 - 5.4e-74 247.0 1.3 6e-74 246.9 1.3 1.0 1 0 0 1 1 1 1 Mago nashi protein HMG_box PF00505.19 CEP10165.1 - 1.9e-16 60.3 0.3 4.6e-16 59.0 0.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP10165.1 - 9.2e-12 45.4 0.3 2.1e-11 44.3 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain 2CSK_N PF08521.10 CEP10165.1 - 0.0079 16.3 0.3 0.018 15.2 0.3 1.6 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal Macoilin PF09726.9 CEP10165.1 - 0.2 10.2 6.6 0.23 10.0 6.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3138 PF11336.8 CEP10165.1 - 2.6 6.6 4.7 11 4.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Cep57_CLD_2 PF14197.6 CEP10165.1 - 5 7.3 12.3 0.63 10.2 7.8 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RNA_pol_Rpc4 PF05132.14 CEP10166.1 - 1.6e-23 83.8 0.0 1.6e-23 83.8 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase III RPC4 PIG-L PF02585.17 CEP10166.1 - 2.5e-23 83.2 0.1 5.6e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Tet_JBP PF12851.7 CEP10167.1 - 0.025 13.9 2.1 0.039 13.3 1.3 1.7 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily TetR_C_27 PF17935.1 CEP10167.1 - 0.056 13.5 1.0 12 6.1 0.0 3.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Phage_int_SAM_2 PF12834.7 CEP10167.1 - 0.17 12.6 1.8 1.7 9.4 0.2 3.1 1 1 0 2 2 2 0 Phage integrase, N-terminal Phage_TAC_12 PF12363.8 CEP10167.1 - 1.3 9.4 12.6 2.7 8.4 2.5 4.0 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC PepSY_like PF11396.8 CEP10167.1 - 3.6 8.2 11.3 1.6 9.3 0.0 4.8 4 2 1 5 5 5 0 Putative beta-lactamase-inhibitor-like, PepSY-like MatP PF06303.12 CEP10167.1 - 9.7 6.8 14.2 7.1 7.3 1.0 5.0 3 2 2 6 6 6 0 MatP N-terminal domain HLH PF00010.26 CEP10168.1 - 8.4e-14 51.3 1.6 8.4e-14 51.3 1.6 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain DUF5345 PF17280.2 CEP10168.1 - 1.9 8.5 4.5 6 6.9 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) NRBF2 PF08961.10 CEP10168.1 - 5.8 6.5 14.0 15 5.1 13.9 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator CK2S PF15011.6 CEP10169.1 - 1.4e-07 31.5 0.6 2.5e-07 30.7 0.6 1.4 1 1 0 1 1 1 1 Casein Kinase 2 substrate NBD94 PF16830.5 CEP10169.1 - 0.041 14.3 0.1 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Med30 PF11315.8 CEP10169.1 - 0.043 14.0 0.3 0.98 9.6 0.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 DASH_Hsk3 PF08227.11 CEP10169.1 - 0.077 13.4 0.4 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like SlyX PF04102.12 CEP10169.1 - 0.19 12.3 0.7 4.4 8.0 0.1 2.3 2 0 0 2 2 2 0 SlyX UNC45-central PF11701.8 CEP10170.1 - 3.9e-36 124.3 7.5 8.7e-34 116.7 0.6 4.4 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 CEP10170.1 - 0.0012 19.1 12.9 0.03 14.7 0.1 5.8 4 3 0 4 4 4 1 HEAT repeats TPR_15 PF13429.6 CEP10170.1 - 0.0083 15.4 5.9 0.056 12.7 2.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP10170.1 - 0.016 15.4 0.1 0.063 13.4 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF410 PF04190.13 CEP10170.1 - 0.068 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF410) Arm_3 PF16186.5 CEP10170.1 - 0.099 12.2 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Atypical Arm repeat DUF4266 PF14086.6 CEP10170.1 - 0.13 13.3 1.8 0.41 11.6 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) ATP-grasp_2 PF08442.10 CEP10170.1 - 1.1 8.8 5.3 0.25 10.9 1.3 2.0 2 0 0 2 2 2 0 ATP-grasp domain HEAT PF02985.22 CEP10170.1 - 2.3 8.7 7.8 16 6.1 0.1 5.7 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 CEP10171.1 - 1.4e-12 47.8 9.5 0.00044 20.7 0.0 8.7 6 3 4 10 10 10 4 HEAT-like repeat HEAT PF02985.22 CEP10171.1 - 2e-07 30.7 5.5 1 9.8 0.1 8.4 9 1 1 10 10 10 2 HEAT repeat IBN_N PF03810.19 CEP10171.1 - 2.1e-07 30.8 1.3 4.1e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CEP10171.1 - 9.8e-07 29.1 0.1 0.71 10.3 0.0 5.5 4 2 1 6 6 6 1 HEAT repeats Arm PF00514.23 CEP10171.1 - 4e-06 26.7 0.4 0.5 10.5 0.0 4.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CEP10171.1 - 0.00016 22.2 0.5 0.96 10.1 0.1 5.1 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CEP10171.1 - 0.001 19.0 1.4 2.4 8.0 0.0 5.4 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) TAF6_C PF07571.13 CEP10171.1 - 0.0032 17.7 0.0 0.61 10.4 0.0 3.7 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain PGA2 PF07543.12 CEP10171.1 - 0.26 11.3 1.7 33 4.5 0.0 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 MMS19_C PF12460.8 CEP10171.1 - 1.3 8.0 11.3 2.4 7.2 0.1 3.9 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CsbD PF05532.12 CEP10172.1 - 1.7e-12 47.0 14.2 4.9e-10 39.2 4.5 2.0 1 1 1 2 2 2 2 CsbD-like DUF883 PF05957.13 CEP10172.1 - 0.06 14.0 1.1 0.085 13.5 0.2 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LRR_4 PF12799.7 CEP10173.1 - 0.00025 21.4 16.1 0.31 11.5 1.1 5.3 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP10173.1 - 0.0007 19.4 18.1 1.2 9.4 1.0 6.3 7 0 0 7 7 7 3 Leucine Rich repeat Inhibitor_I10 PF12559.8 CEP10173.1 - 1.2 9.4 4.4 34 4.8 5.3 2.3 2 0 0 2 2 2 0 Serine endopeptidase inhibitors LRR_1 PF00560.33 CEP10173.1 - 4.2 8.3 16.3 1.1e+02 4.0 0.2 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat Ribosomal_L15e PF00827.17 CEP10174.1 - 9e-89 296.3 9.7 1e-88 296.1 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 ECH_1 PF00378.20 CEP10175.1 - 8.1e-41 140.0 0.0 1.1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP10175.1 - 1.1e-15 58.0 0.0 1.3e-15 57.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CFEM PF05730.11 CEP10176.1 - 7.1 6.8 12.3 3.9 7.6 9.1 2.2 1 1 1 2 2 2 0 CFEM domain Asp PF00026.23 CEP10177.1 - 6e-36 124.5 0.4 3.9e-35 121.8 0.4 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP10177.1 - 3.2e-11 43.8 0.7 1e-08 35.6 0.7 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal HA2 PF04408.23 CEP10178.1 - 5.6e-17 62.0 0.2 2e-16 60.2 0.0 2.2 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP10178.1 - 2.9e-14 53.3 0.0 9.7e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEP10178.1 - 5.4e-11 42.7 0.0 2.2e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CEP10178.1 - 5.8e-06 26.2 0.3 1.5e-05 24.8 0.3 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP10178.1 - 6.3e-05 23.3 0.1 0.00017 21.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CEP10178.1 - 0.00013 22.0 1.1 0.00019 21.4 0.1 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 CEP10178.1 - 0.00033 21.0 0.1 0.0007 19.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CEP10178.1 - 0.0014 18.6 0.1 0.0059 16.6 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PAGK PF15284.6 CEP10178.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 Phage-encoded virulence factor T2SSE PF00437.20 CEP10178.1 - 0.035 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CEP10178.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CEP10178.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CEP10178.1 - 0.15 12.6 6.7 0.66 10.5 0.0 3.5 3 1 1 4 4 4 0 ABC transporter AAA_16 PF13191.6 CEP10178.1 - 0.35 11.2 1.1 0.86 10.0 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CEP10178.1 - 3.2 8.2 0.0 3.2 8.2 0.0 3.9 4 1 0 4 4 2 0 AAA domain Ribosomal_L16 PF00252.18 CEP10179.1 - 1.7e-44 151.0 0.1 2e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1151 PF06625.11 CEP10180.1 - 3.2 7.7 13.4 0.028 14.4 2.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1151) PA PF02225.22 CEP10181.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.7 1 1 1 2 2 2 0 PA domain rve PF00665.26 CEP10183.1 - 3.7e-05 23.9 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CEP10184.1 - 4.9e-32 109.9 0.0 7.5e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10184.1 - 5.5e-29 100.5 0.0 8.4e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 CEP10184.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase-like Tropomyosin PF00261.20 CEP10184.1 - 0.099 12.0 0.3 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Tropomyosin Glyco_transf_20 PF00982.21 CEP10185.1 - 5.4e-162 539.8 0.0 7.9e-162 539.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP10185.1 - 2.2e-72 243.0 0.0 4.3e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Ncstrn_small PF18266.1 CEP10185.1 - 4.6e-35 121.1 0.1 1.1e-34 119.9 0.1 1.7 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 CEP10185.1 - 2.2e-32 112.4 3.3 4.5e-31 108.1 3.3 2.5 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 CEP10185.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Snf7 PF03357.21 CEP10186.1 - 1.6e-45 154.8 23.4 3.4e-45 153.7 23.4 1.6 1 0 0 1 1 1 1 Snf7 FHA PF00498.26 CEP10186.1 - 1e-05 25.8 0.1 2.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 FHA domain NPV_P10 PF05531.12 CEP10186.1 - 0.44 11.1 13.5 0.29 11.6 3.2 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PEP-utilisers_N PF05524.13 CEP10186.1 - 3.3 7.9 5.5 2.9 8.1 3.0 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF948 PF06103.11 CEP10186.1 - 4.5 7.6 6.2 3.7 7.9 1.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 CEP10186.1 - 5.6 7.4 11.4 2.1 8.8 0.5 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_L27A PF00828.19 CEP10186.1 - 8.5 7.1 8.3 15 6.3 0.9 3.3 2 1 1 3 3 3 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TAF4 PF05236.14 CEP10187.1 - 6.2e-16 59.0 0.0 6.2e-16 59.0 0.0 4.0 4 1 1 5 5 5 2 Transcription initiation factor TFIID component TAF4 family Usp PF00582.26 CEP10188.1 - 2e-26 93.2 0.4 5.8e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family Oxidored_nitro PF00148.19 CEP10188.1 - 0.021 13.6 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Chitin_synth_1 PF01644.17 CEP10189.1 - 5.1e-79 263.9 0.5 2.8e-78 261.5 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 CEP10189.1 - 4.5e-28 97.0 0.1 1.5e-27 95.3 0.1 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEP10189.1 - 1.2e-19 70.3 3.5 7.6e-17 61.1 0.1 2.3 1 1 0 2 2 2 2 Chitin synthase RRM_1 PF00076.22 CEP10189.1 - 4.1e-14 52.2 0.0 1.3e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_trans_2_3 PF13632.6 CEP10189.1 - 2.5e-05 24.3 10.0 0.00023 21.1 10.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 CitMHS PF03600.16 CEP10189.1 - 0.009 15.2 0.3 0.014 14.6 0.3 1.3 1 0 0 1 1 1 1 Citrate transporter GYR PF02756.14 CEP10189.1 - 0.54 10.0 3.1 1.7 8.4 3.1 1.9 1 0 0 1 1 1 0 GYR motif Kelch_1 PF01344.25 CEP10190.1 - 7.3e-07 28.7 4.5 0.22 11.1 0.8 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CEP10190.1 - 5.8e-06 26.1 1.4 5 7.3 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CEP10190.1 - 0.0048 17.2 6.5 8.5 6.8 0.2 5.9 5 1 1 6 6 6 1 Kelch motif OLF PF02191.16 CEP10190.1 - 0.051 13.1 8.6 0.83 9.1 0.0 2.8 3 1 1 4 4 4 0 Olfactomedin-like domain Kelch_4 PF13418.6 CEP10190.1 - 0.15 12.1 2.9 3.6 7.7 0.1 4.3 6 0 0 6 6 6 0 Galactose oxidase, central domain PHZA_PHZB PF03284.13 CEP10190.1 - 0.18 11.4 1.3 1.1 8.9 1.3 2.0 1 1 0 1 1 1 0 Phenazine biosynthesis protein A/B Kelch_3 PF13415.6 CEP10190.1 - 0.35 11.2 1.8 6.3 7.2 0.2 3.8 3 1 1 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP10191.1 - 1.4e-08 34.7 5.4 0.004 17.4 0.0 5.3 3 1 2 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CEP10191.1 - 2.6e-06 27.2 2.5 1.2 9.2 0.1 5.2 5 2 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CEP10191.1 - 9.2e-05 22.0 7.0 0.015 14.9 1.6 4.0 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CEP10191.1 - 0.00013 21.9 15.0 2.1 8.4 2.0 5.8 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CEP10191.1 - 0.0011 19.2 8.3 4.9 7.6 0.7 4.3 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP10191.1 - 0.0055 16.7 0.1 1.3 9.1 0.0 3.9 4 0 0 4 4 4 1 Kelch motif RRP7 PF12923.7 CEP10192.1 - 0.051 13.7 0.3 0.051 13.7 0.3 1.5 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain NDC10_II PF16787.5 CEP10192.1 - 0.055 12.5 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Spc24 PF08286.11 CEP10192.1 - 1.2 9.4 4.3 2.5 8.4 1.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Aa_trans PF01490.18 CEP10193.1 - 3.6e-45 154.4 22.7 4.6e-45 154.1 22.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAPS PF04499.15 CEP10194.1 - 2.3e-113 379.6 2.1 5.8e-62 210.1 1.1 3.4 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein SE PF08491.10 CEP10195.1 - 4.2e-101 337.6 0.1 5.9e-101 337.1 0.1 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CEP10195.1 - 9.9e-13 48.1 0.0 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CEP10195.1 - 6.6e-06 25.5 0.2 4.5e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 CEP10195.1 - 0.00017 21.3 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP10195.1 - 0.0013 17.9 2.4 0.25 10.4 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CEP10195.1 - 0.0016 18.6 0.5 0.0038 17.4 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP10195.1 - 0.0019 17.5 0.4 0.0042 16.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CEP10195.1 - 0.0044 16.4 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CEP10195.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CEP10195.1 - 0.06 13.9 0.9 0.82 10.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP10195.1 - 0.065 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 CEP10195.1 - 0.15 11.3 0.8 0.31 10.2 0.6 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CEP10195.1 - 0.21 11.5 0.6 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_synthFbeta PF17759.1 CEP10196.1 - 1.4e-45 155.3 0.0 2.1e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CEP10196.1 - 1e-29 102.6 0.3 3.4e-29 100.9 0.1 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CEP10196.1 - 2.7e-27 95.5 0.1 4.9e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CEP10196.1 - 5e-21 74.8 0.0 3.9e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 CEP10196.1 - 0.042 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Herpes_V23 PF01802.17 CEP10196.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein T6PP_N PF18572.1 CEP10196.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SH3BGR PF04908.15 CEP10197.1 - 9.7e-14 51.3 2.7 1.3e-13 50.9 0.0 2.8 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CEP10197.1 - 7.1e-05 23.0 0.0 0.00025 21.2 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin DAGK_cat PF00781.24 CEP10197.1 - 0.015 14.9 1.6 0.13 11.9 0.0 3.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain LAM_C PF12544.8 CEP10197.1 - 0.04 14.1 0.1 0.04 14.1 0.1 3.1 3 1 1 4 4 4 0 Lysine-2,3-aminomutase DUF1574 PF07611.11 CEP10197.1 - 0.089 12.1 0.0 0.089 12.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1574) LRR_8 PF13855.6 CEP10198.1 - 2.3e-29 100.9 36.6 1.8e-07 30.8 0.1 8.3 4 2 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 CEP10198.1 - 2.9e-29 100.6 35.9 7e-05 23.1 0.0 8.1 8 0 0 8 8 8 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEP10198.1 - 3.5e-09 36.4 14.6 0.00067 19.2 0.8 5.2 3 1 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 CEP10198.1 - 4.2 7.7 27.2 6.1 7.2 0.3 8.5 10 0 0 10 10 10 0 Leucine Rich repeat DUF202 PF02656.15 CEP10200.1 - 5e-14 52.5 4.0 5e-14 52.5 4.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Sarcolipin PF05366.11 CEP10200.1 - 4.6 7.0 7.9 3 7.6 0.1 3.4 4 0 0 4 4 4 0 Sarcolipin Alg14 PF08660.11 CEP10201.1 - 8.9e-59 198.3 0.0 1.4e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Aminotran_1_2 PF00155.21 CEP10201.1 - 1.6e-55 188.7 0.0 2.5e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP10201.1 - 0.0038 16.5 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cullin_Nedd8 PF10557.9 CEP10201.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Cullin protein neddylation domain RRM_1 PF00076.22 CEP10202.1 - 1.1e-48 162.9 1.4 1.1e-21 76.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CEP10202.1 - 3.4e-17 63.3 0.5 1.5e-16 61.3 0.5 2.1 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CEP10202.1 - 6e-06 26.0 0.0 0.16 11.8 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CEP10202.1 - 0.00026 20.6 0.0 1.1 8.9 0.0 3.2 2 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP10202.1 - 0.00028 20.9 0.1 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 CEP10202.1 - 0.014 15.4 0.0 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_9 PF18444.1 CEP10202.1 - 0.052 13.4 0.5 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 RNA recognition motif RRM_7 PF16367.5 CEP10202.1 - 0.13 12.4 0.1 9.2 6.5 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif RSRP PF17069.5 CEP10202.1 - 1.9 8.0 53.7 3 7.3 53.7 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Apt1 PF10351.9 CEP10202.1 - 4.2 6.1 17.6 5.9 5.6 17.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2457 PF10446.9 CEP10202.1 - 5.4 6.0 28.6 9.5 5.2 28.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Presenilin PF01080.17 CEP10202.1 - 7.5 5.2 12.6 10 4.8 12.6 1.1 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 CEP10203.1 - 1.8e-10 40.7 9.0 0.00012 22.4 3.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP10203.1 - 2.8e-09 37.0 10.6 4.3e-06 26.9 0.8 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP10203.1 - 7.2e-05 23.3 6.5 0.0085 16.8 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CEP10203.1 - 0.00027 21.2 0.6 0.00027 21.2 0.6 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEP10203.1 - 0.0011 18.9 4.1 0.0018 18.2 0.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CEP10203.1 - 0.069 13.1 4.1 5.3 7.1 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TFIIA PF03153.13 CEP10203.1 - 0.1 12.6 10.2 0.13 12.2 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_11 PF16622.5 CEP10203.1 - 0.14 11.9 4.8 0.44 10.4 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DHHC PF01529.20 CEP10204.1 - 8.3e-05 22.7 7.8 8.3e-05 22.7 7.8 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2628 PF10947.8 CEP10204.1 - 0.041 14.2 0.2 0.059 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) AMP-binding PF00501.28 CEP10205.1 - 6.9e-74 248.9 0.4 4.8e-31 107.8 0.1 3.4 3 0 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 CEP10205.1 - 1.7e-10 41.6 3.1 1.7e-10 41.6 3.1 3.2 2 1 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 CEP10205.1 - 0.068 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Gas vesicle protein G SUIM_assoc PF16619.5 CEP10205.1 - 0.27 11.3 17.9 0.023 14.7 1.7 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CEP10205.1 - 1.1 10.1 13.4 3.9 8.4 13.4 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CEP10205.1 - 1.5 8.4 15.3 3.7 7.1 15.3 1.6 1 0 0 1 1 1 0 Spt20 family Hydrolase_4 PF12146.8 CEP10207.1 - 3.6e-12 46.1 0.0 7.8e-06 25.3 0.1 3.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP10207.1 - 1.2e-07 31.7 0.1 0.0092 15.7 0.0 3.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEP10207.1 - 0.0093 15.5 0.0 0.082 12.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CEP10207.1 - 0.027 14.0 0.0 0.057 13.0 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CEP10207.1 - 0.03 14.1 0.0 0.34 10.7 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CEP10207.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CEP10207.1 - 0.2 12.2 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4303 PF14136.6 CEP10208.1 - 0.054 13.2 0.0 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) WD40 PF00400.32 CEP10209.1 - 1.1e-23 83.1 6.3 8.2e-08 32.8 1.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP10209.1 - 1.1e-08 35.2 0.1 0.032 14.5 0.0 4.9 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CEP10209.1 - 0.0047 15.5 0.0 0.67 8.4 0.0 2.7 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 CEP10209.1 - 0.0085 14.8 0.2 2.9 6.4 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Mt_ATP-synt_B PF05405.14 CEP10210.1 - 4.6e-46 156.4 6.9 6.4e-46 156.0 6.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TFA2_Winged_2 PF18121.1 CEP10211.1 - 4.6e-19 67.9 0.1 8.8e-19 67.0 0.1 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CEP10211.1 - 4.7e-18 65.2 0.8 1.8e-17 63.4 0.2 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain HALZ PF02183.18 CEP10211.1 - 0.036 14.3 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Response_reg PF00072.24 CEP10212.1 - 1.1e-27 96.4 0.8 7.8e-27 93.7 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 CEP10212.1 - 1e-26 93.4 1.3 1e-26 93.4 1.3 2.6 2 0 0 2 2 2 1 HSF-type DNA-binding CLZ PF16526.5 CEP10212.1 - 0.0068 16.7 1.1 0.024 15.0 1.1 2.0 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRCT_3 PF18428.1 CEP10212.1 - 0.016 15.3 0.9 1 9.4 0.0 3.4 3 1 1 4 4 4 0 BRCA1 C Terminus (BRCT) domain Invasin_D3 PF09134.10 CEP10212.1 - 0.032 14.5 2.5 0.2 12.0 0.1 3.0 2 0 0 2 2 2 0 Invasin, domain 3 DUF1664 PF07889.12 CEP10212.1 - 0.21 11.6 3.4 0.61 10.1 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2433 PF10360.9 CEP10212.1 - 0.28 11.3 5.1 5.6 7.1 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) Pkinase PF00069.25 CEP10213.1 - 7e-41 140.3 2.7 7e-34 117.4 0.1 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10213.1 - 2.3e-22 79.5 0.0 1.2e-20 73.9 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP10213.1 - 2.7e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 CEP10213.1 - 0.017 14.1 0.3 0.028 13.4 0.3 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CEP10213.1 - 0.077 12.9 0.3 0.41 10.5 0.5 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CEP10214.1 - 2.5e-11 43.4 12.7 7.1e-06 26.2 3.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP10214.1 - 7.8e-11 41.9 18.5 1.2e-05 25.5 5.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP10214.1 - 2.3e-06 28.0 10.5 0.0087 16.8 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP10214.1 - 0.0092 16.2 2.5 0.17 12.2 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEP10214.1 - 0.014 16.0 1.7 0.017 15.7 0.1 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 CEP10214.1 - 0.13 12.7 1.1 4.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CEP10214.1 - 0.26 11.6 3.4 0.5 10.7 3.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CEP10214.1 - 0.27 11.0 11.7 0.47 10.3 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF2225 PF09986.9 CEP10214.1 - 1.8 8.2 3.9 3.1 7.4 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) RNase_PH PF01138.21 CEP10215.1 - 7.2e-26 91.2 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP10215.1 - 4.8e-07 29.7 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MFS_1_like PF12832.7 CEP10216.1 - 1e-72 245.2 11.2 1.4e-72 244.7 11.2 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CEP10216.1 - 5.8e-21 74.8 49.8 2.7e-11 43.0 8.0 3.7 1 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CEP10216.1 - 8.8e-16 57.9 2.6 8.8e-16 57.9 2.6 2.4 2 1 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 CEP10216.1 - 1.1e-06 27.7 2.9 1.1e-06 27.7 2.9 2.2 2 1 0 2 2 2 1 LacY proton/sugar symporter ATG22 PF11700.8 CEP10216.1 - 0.04 12.6 19.4 0.066 11.8 7.6 3.4 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like Ceramidase PF05875.12 CEP10216.1 - 0.057 12.8 2.2 0.093 12.1 1.2 1.9 1 1 0 1 1 1 0 Ceramidase Shisa PF13908.6 CEP10216.1 - 5.5 7.2 8.5 0.071 13.4 0.9 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TssN PF17555.2 CEP10216.1 - 6.5 6.0 8.7 0.17 11.3 1.7 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN SapB_1 PF05184.15 CEP10217.1 - 0.79 9.8 2.5 0.59 10.2 0.6 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 WD40 PF00400.32 CEP10218.1 - 4.3e-28 97.0 3.7 1.9e-06 28.5 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP10218.1 - 1.1e-13 51.3 0.1 8.8e-05 22.7 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CEP10218.1 - 1.9e-10 40.2 0.6 3.8e-10 39.3 0.6 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CEP10218.1 - 1.9e-06 27.1 0.6 0.069 12.1 0.1 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP10218.1 - 2.7e-06 26.3 0.4 0.027 13.1 0.1 3.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP10218.1 - 1.2e-05 24.8 0.8 0.0047 16.3 0.2 3.1 3 0 0 3 3 3 2 WD40-like domain PALB2_WD40 PF16756.5 CEP10218.1 - 0.025 13.5 0.3 0.25 10.2 0.0 2.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain ORC2 PF04084.14 CEP10219.1 - 4.2e-115 384.2 0.0 7.9e-115 383.3 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RhoGAP PF00620.27 CEP10220.1 - 6.8e-44 149.4 0.1 1.4e-43 148.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Tox-ODYAM1 PF15642.6 CEP10220.1 - 0.0029 16.7 2.2 0.0061 15.6 2.2 1.5 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus ZapB PF06005.12 CEP10220.1 - 0.0056 17.1 5.4 0.025 15.0 5.4 2.1 1 0 0 1 1 1 1 Cell division protein ZapB K-box PF01486.17 CEP10220.1 - 0.092 12.9 7.5 0.27 11.4 4.4 2.8 2 0 0 2 2 2 0 K-box region DUF2569 PF10754.9 CEP10221.1 - 0.15 12.5 5.6 0.25 11.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4181 PF13789.6 CEP10221.1 - 0.32 11.3 3.7 0.48 10.7 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Adaptin_N PF01602.20 CEP10222.1 - 1.1e-46 159.6 13.1 1.4e-46 159.1 13.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 CEP10222.1 - 7.9e-10 39.0 0.2 2.6e-09 37.4 0.2 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 CEP10222.1 - 3.1e-07 30.6 0.0 3.1e-07 30.6 0.0 2.6 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP10222.1 - 0.0015 18.9 0.1 0.015 15.6 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats SRF-TF PF00319.18 CEP10223.1 - 1.5e-21 75.6 0.1 2.2e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2722 PF10846.8 CEP10223.1 - 0.0022 17.0 4.3 0.0032 16.5 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CEP10223.1 - 0.0044 17.1 9.9 0.0044 17.1 9.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CEP10223.1 - 0.14 12.8 8.9 0.19 12.4 8.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IER PF05760.12 CEP10223.1 - 0.16 12.2 4.0 0.22 11.8 4.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF908 PF06012.12 CEP10223.1 - 0.76 9.1 6.4 1 8.7 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FTZ PF03867.14 CEP10223.1 - 1.3 8.5 8.3 1.8 8.0 8.3 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Spt20 PF12090.8 CEP10223.1 - 2.1 7.9 16.3 3.2 7.3 16.3 1.3 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 CEP10223.1 - 6.6 7.0 6.1 11 6.3 5.3 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DDE_3 PF13358.6 CEP10225.1 - 9.5e-16 57.9 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease U3_snoRNA_assoc PF08297.11 CEP10225.1 - 0.054 14.2 1.3 0.76 10.5 0.3 2.4 2 0 0 2 2 2 0 U3 snoRNA associated Ribosomal_S13 PF00416.22 CEP10226.1 - 1e-52 177.9 2.4 1.3e-52 177.5 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEP10226.1 - 0.02 13.7 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 CEP10226.1 - 0.036 14.5 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF1822 PF08852.11 CEP10226.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) Pkinase PF00069.25 CEP10227.1 - 6.4e-75 251.9 0.0 9.2e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10227.1 - 7.2e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP10227.1 - 6.6e-06 25.6 0.0 9e-05 21.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP10227.1 - 0.0086 14.9 0.1 0.0086 14.9 0.1 2.7 2 1 0 2 2 2 1 Fungal protein kinase Aconitase PF00330.20 CEP10228.1 - 1.3e-153 512.4 0.0 1.9e-153 511.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP10228.1 - 5.6e-40 136.7 0.1 1.2e-39 135.6 0.1 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain BET PF17035.5 CEP10229.1 - 3.3e-07 30.4 3.6 9.4e-07 28.9 3.6 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SR-25 PF10500.9 CEP10229.1 - 1.4e-05 24.9 23.6 0.00014 21.6 4.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein GP67 PF17634.2 CEP10230.1 - 0.23 11.9 6.2 16 6.0 1.9 3.4 3 0 0 3 3 3 0 Gene product 67 Myc_N PF01056.18 CEP10231.1 - 0.0021 18.0 2.6 0.0025 17.8 2.6 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Nucleo_P87 PF07267.11 CEP10231.1 - 0.011 14.6 3.6 0.012 14.5 3.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.14 CEP10231.1 - 0.036 13.8 3.2 0.055 13.3 3.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 CEP10231.1 - 0.053 12.7 8.1 0.073 12.2 8.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 CEP10231.1 - 0.11 11.9 7.5 0.14 11.4 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein LAT PF15234.6 CEP10231.1 - 0.31 10.7 10.6 0.34 10.6 9.7 1.4 1 1 0 1 1 1 0 Linker for activation of T-cells FAM176 PF14851.6 CEP10231.1 - 1.2 8.8 7.3 1.8 8.2 7.3 1.3 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 CEP10231.1 - 3.7 7.7 17.3 7.1 6.8 17.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 CEP10232.1 - 0.028 13.6 1.4 0.037 13.2 1.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 CEP10232.1 - 0.054 13.5 3.0 0.08 13.0 3.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CEP10232.1 - 0.061 12.7 6.8 0.089 12.1 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CEP10232.1 - 0.71 9.5 6.7 1.3 8.7 6.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 CEP10232.1 - 0.96 9.7 11.5 1.7 9.0 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleo_P87 PF07267.11 CEP10232.1 - 1.5 7.6 6.9 2 7.2 6.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 CEP10232.1 - 6.9 4.8 8.2 8.8 4.5 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAP PF07174.11 CEP10232.1 - 7.7 5.9 22.5 9.8 5.5 22.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RR_TM4-6 PF06459.12 CEP10233.1 - 0.019 14.8 9.8 0.03 14.2 9.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CEP10233.1 - 0.066 12.6 26.3 0.11 11.8 26.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 CEP10233.1 - 0.1 11.4 3.8 0.099 11.4 3.8 1.2 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 CEP10233.1 - 0.33 11.3 13.6 0.6 10.4 13.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ORC_WH_C PF18137.1 CEP10233.1 - 0.37 10.9 13.7 0.38 10.8 12.7 1.5 2 0 0 2 2 1 0 Origin recognition complex winged helix C-terminal SAPS PF04499.15 CEP10233.1 - 0.51 9.1 9.7 0.54 9.0 9.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 CEP10233.1 - 0.52 10.5 10.0 1 9.5 10.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5523 PF17661.1 CEP10233.1 - 0.53 9.9 22.0 1 9.0 22.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2457 PF10446.9 CEP10233.1 - 0.8 8.8 41.5 1.4 8.0 41.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RPN2_C PF18004.1 CEP10233.1 - 0.83 9.6 14.4 1.7 8.5 14.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_polI_A34 PF08208.11 CEP10233.1 - 0.88 9.6 11.9 1.8 8.6 11.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HABP4_PAI-RBP1 PF04774.15 CEP10233.1 - 0.91 10.4 24.0 2.2 9.2 24.0 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Tim54 PF11711.8 CEP10233.1 - 0.95 8.2 12.8 1.4 7.6 12.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CEP10233.1 - 0.96 9.2 6.1 1.5 8.5 6.1 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 CEP10233.1 - 1.2 8.9 3.7 2 8.1 3.7 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ADP_ribosyl_GH PF03747.14 CEP10233.1 - 1.2 8.8 4.6 1.9 8.2 4.6 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase MRNIP PF15749.5 CEP10233.1 - 1.3 9.8 8.7 3 8.6 8.7 1.6 1 0 0 1 1 1 0 MRN-interacting protein Serinc PF03348.15 CEP10233.1 - 1.4 7.7 6.3 2.5 6.9 6.3 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF719 PF05334.13 CEP10233.1 - 1.5 9.0 9.1 1.1 9.4 6.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Nucleo_P87 PF07267.11 CEP10233.1 - 2.2 7.0 9.9 3.2 6.5 9.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FmiP_Thoc5 PF09766.9 CEP10233.1 - 2.3 7.4 12.3 3.2 6.9 12.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Nop25 PF09805.9 CEP10233.1 - 3.1 8.3 26.5 3.4 8.1 23.4 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF4637 PF15470.6 CEP10233.1 - 3.2 7.5 25.6 7 6.4 25.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 CEP10233.1 - 3.3 5.9 25.8 6 5.0 25.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CEP10233.1 - 4.4 7.4 7.4 3.7 7.6 6.1 1.4 1 1 0 1 1 1 0 DDHD domain DUF3306 PF11748.8 CEP10233.1 - 6.6 7.6 18.0 11 6.9 15.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) FYDLN_acid PF09538.10 CEP10233.1 - 6.7 7.4 36.7 1.8 9.3 24.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4746 PF15928.5 CEP10233.1 - 7.1 6.0 20.9 15 4.9 20.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 CEP10233.1 - 7.3 5.5 11.7 1.6 7.7 8.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 CEP10233.1 - 8.4 4.8 24.5 15 4.0 24.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.22 CEP10233.1 - 8.7 5.5 7.4 16 4.6 7.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DDRGK PF09756.9 CEP10233.1 - 9.2 5.8 22.7 17 5.0 22.7 1.3 1 0 0 1 1 1 0 DDRGK domain CDC27 PF09507.10 CEP10234.1 - 8.6 5.6 45.5 13 5.1 45.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NDC10_II PF16787.5 CEP10235.1 - 0.001 18.2 0.1 0.0016 17.5 0.1 1.3 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 bZIP_1 PF00170.21 CEP10236.1 - 6.8e-08 32.5 19.1 5e-07 29.7 19.1 2.2 1 1 0 1 1 1 1 bZIP transcription factor HAUS6_N PF14661.6 CEP10236.1 - 0.0021 17.7 1.5 0.003 17.2 1.5 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.8 CEP10236.1 - 0.0065 15.8 1.2 0.0092 15.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.6 CEP10236.1 - 0.0066 16.5 4.3 0.02 15.0 4.3 1.9 1 0 0 1 1 1 1 Sperm tail C-terminal domain Retrotrans_gag PF03732.17 CEP10236.1 - 0.014 15.7 0.9 0.041 14.2 0.9 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein UPF0242 PF06785.11 CEP10236.1 - 0.023 14.8 4.8 0.033 14.3 4.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 CEP10236.1 - 0.63 9.8 7.0 0.32 10.8 4.4 1.8 1 1 1 2 2 2 0 Septum formation initiator PEARLI-4 PF05278.12 CEP10236.1 - 0.76 9.3 5.3 1.6 8.2 5.3 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) bZIP_2 PF07716.15 CEP10236.1 - 4.7 7.4 26.0 0.89 9.7 7.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Aminotran_1_2 PF00155.21 CEP10237.1 - 1.3e-21 77.2 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEP10237.1 - 0.0003 19.7 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase EIIBC-GUT_C PF07663.11 CEP10237.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II C-terminus Minor_capsid_1 PF10665.9 CEP10237.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein CUE PF02845.16 CEP10239.1 - 0.083 12.6 1.2 0.45 10.3 0.1 2.2 2 0 0 2 2 2 0 CUE domain DUF4837 PF16125.5 CEP10240.1 - 0.0029 16.7 0.0 0.0035 16.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4837) ErmC PF06308.11 CEP10240.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) MscS_TM PF12794.7 CEP10241.1 - 0.31 9.9 0.4 0.28 10.0 0.4 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FliT PF05400.13 CEP10245.1 - 0.0032 18.2 0.7 0.0083 16.9 0.7 1.6 1 0 0 1 1 1 1 Flagellar protein FliT DDT PF02791.17 CEP10245.1 - 0.015 15.6 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 DDT domain GCIP PF13324.6 CEP10246.1 - 0.033 13.8 0.5 0.04 13.5 0.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Retrotrans_gag PF03732.17 CEP10247.1 - 6.4e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 2 1 0 2 2 2 1 Retrotransposon gag protein Cytochrom_C550 PF14495.6 CEP10247.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.5 2 0 0 2 2 2 0 Cytochrome c-550 domain DDE_3 PF13358.6 CEP10248.1 - 3.6e-13 49.5 0.0 1.3e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.14 CEP10250.1 - 6.9e-05 22.2 0.0 8.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase T2SSE PF00437.20 CEP10250.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Exo_endo_phos_2 PF14529.6 CEP10254.1 - 6.3e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP10254.1 - 5.6e-05 22.8 0.2 0.0001 21.9 0.2 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PrgU PF09627.10 CEP10256.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 PrgU-like protein zf-CCHC PF00098.23 CEP10258.1 - 0.044 13.9 2.6 0.068 13.3 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 CEP10260.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Integrase zinc binding domain RVT_1 PF00078.27 CEP10261.1 - 0.004 16.7 0.2 0.0079 15.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP10262.1 - 7.4e-17 61.6 0.0 1.3e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP10262.1 - 0.0037 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain OrfB_Zn_ribbon PF07282.11 CEP10263.1 - 0.0043 17.0 0.5 0.0043 17.0 0.5 1.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain BIR PF00653.21 CEP10263.1 - 0.08 13.6 0.1 0.12 13.0 0.1 1.3 1 1 0 1 1 1 0 Inhibitor of Apoptosis domain Acid_phosphat_B PF03767.14 CEP10263.1 - 0.08 12.5 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) ACT_7 PF13840.6 CEP10263.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 ACT domain Pkinase PF00069.25 CEP10264.1 - 7.7e-57 192.6 0.0 2.2e-56 191.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10264.1 - 1.1e-30 106.8 0.2 1.8e-29 102.8 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP10264.1 - 0.0057 16.0 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family NTP_transferase PF00483.23 CEP10265.1 - 6.8e-55 186.3 0.0 1.1e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEP10265.1 - 3.8e-13 48.6 6.0 2e-10 40.0 3.2 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEP10265.1 - 3.6e-10 40.4 0.0 5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CEP10265.1 - 1.3e-05 24.8 2.8 1.3e-05 24.8 2.8 2.8 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CEP10265.1 - 0.0064 14.7 0.2 0.0094 14.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) SRP54 PF00448.22 CEP10265.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fucokinase PF07959.12 CEP10265.1 - 0.087 11.7 0.0 0.39 9.6 0.0 2.0 2 1 0 2 2 2 0 L-fucokinase DUF2810 PF10928.8 CEP10265.1 - 0.18 11.9 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Glycos_transf_3 PF00591.21 CEP10267.1 - 3.5e-87 292.2 1.1 5.3e-87 291.6 1.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CEP10267.1 - 4.7e-16 58.4 0.0 9.4e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF202 PF02656.15 CEP10268.1 - 1.9e-14 53.8 4.6 1.9e-14 53.8 4.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.6 CEP10268.1 - 0.0057 16.7 1.6 0.0066 16.5 1.6 1.2 1 0 0 1 1 1 1 CoA-binding domain TRAP-gamma PF07074.12 CEP10268.1 - 0.27 10.8 2.4 0.9 9.1 2.5 1.8 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Sin3a_C PF16879.5 CEP10269.1 - 2e-69 234.5 6.2 2e-69 234.5 6.2 3.0 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 CEP10269.1 - 8.2e-44 147.5 10.0 2.4e-17 62.8 0.0 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CEP10269.1 - 1.3e-37 127.8 0.3 1.3e-37 127.8 0.3 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor TMEM214 PF10151.9 CEP10269.1 - 0.079 11.4 0.7 0.18 10.2 0.7 1.5 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator HAMP PF00672.25 CEP10270.1 - 1.1e-208 675.7 99.2 5.1e-09 36.4 0.1 28.3 27 0 0 27 27 27 26 HAMP domain HATPase_c PF02518.26 CEP10270.1 - 2.6e-31 108.4 0.1 2.5e-30 105.2 0.1 3.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP10270.1 - 2.1e-25 89.0 0.3 2.1e-25 89.0 0.3 5.3 5 0 0 5 5 5 1 Response regulator receiver domain HisKA PF00512.25 CEP10270.1 - 7.5e-17 61.1 4.1 3.5e-16 59.0 0.5 4.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.17 CEP10270.1 - 3.8e-15 55.6 12.5 27 4.9 0.0 19.4 23 0 0 23 23 23 0 Helix-turn-helix domain, rpiR family ImcF-related_N PF14331.6 CEP10270.1 - 2e-10 40.5 8.6 25 4.1 0.0 14.4 13 3 3 16 16 16 0 ImcF-related N-terminal domain DUF4279 PF14106.6 CEP10270.1 - 5e-08 33.1 0.0 24 5.2 0.0 13.0 19 0 0 19 19 19 0 Domain of unknown function (DUF4279) WXG100 PF06013.12 CEP10270.1 - 0.0086 16.3 64.7 0.25 11.6 0.1 19.9 19 6 6 26 26 26 2 Proteins of 100 residues with WXG SpoIIID PF12116.8 CEP10270.1 - 0.14 12.2 54.0 40 4.4 0.1 19.1 25 0 0 25 25 25 0 Stage III sporulation protein D DUF2235 PF09994.9 CEP10270.1 - 5.1 6.4 11.1 1.1e+02 2.0 0.0 5.8 5 0 0 5 5 5 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Homeodomain PF00046.29 CEP10271.1 - 8.1e-19 67.2 2.6 2e-18 66.0 2.6 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP10271.1 - 0.0049 16.7 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Porphyrn_cat_1 PF18206.1 CEP10271.1 - 0.13 12.9 0.8 0.3 11.7 0.2 2.0 1 1 1 2 2 2 0 Porphyranase catalytic subdomain 1 AlaDh_PNT_C PF01262.21 CEP10272.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RT_RNaseH_2 PF17919.1 CEP10273.1 - 1.1e-36 124.9 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10273.1 - 1.9e-36 124.5 0.0 5.3e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP10273.1 - 1.7e-20 73.4 0.0 2.3e-19 69.8 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP10273.1 - 7.2e-20 70.8 0.1 1.4e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CEP10273.1 - 2e-05 24.2 0.0 4.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CEP10273.1 - 7.9e-05 22.4 0.1 0.00067 19.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain DNA_pol_viral_C PF00336.18 CEP10273.1 - 0.05 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Pro_isomerase PF00160.21 CEP10276.1 - 7e-49 166.1 0.1 1.1e-48 165.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CEP10276.1 - 1.1e-05 25.1 8.1 0.053 13.7 0.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10276.1 - 0.0002 21.0 8.4 0.0033 17.2 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10276.1 - 0.0023 17.6 4.1 0.02 14.6 1.0 2.6 2 1 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 CEP10276.1 - 0.37 11.5 2.1 5.9 7.8 0.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP10276.1 - 1 10.1 3.9 25 5.6 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP10276.1 - 4.7 7.7 8.5 0.78 10.1 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_4 PF13462.6 CEP10277.1 - 2e-11 44.3 0.0 3.6e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 CEP10277.1 - 0.0005 19.9 2.2 0.087 12.6 1.0 2.3 1 1 0 2 2 2 2 DSBA-like thioredoxin domain Proteasome PF00227.26 CEP10278.1 - 5e-45 153.3 0.0 5.7e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3292 PF11696.8 CEP10279.1 - 2.1e-15 56.2 7.7 6.1e-09 34.8 0.5 3.4 2 2 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 CEP10279.1 - 3.2e-06 27.0 1.5 2.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 CEP10279.1 - 0.0089 16.0 3.2 0.21 11.5 0.3 2.5 2 0 0 2 2 2 2 Reticulon DUF639 PF04842.12 CEP10279.1 - 0.045 13.2 1.9 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) FA_desaturase PF00487.24 CEP10279.1 - 0.22 11.3 3.3 0.42 10.4 0.6 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF4749 PF15936.5 CEP10280.1 - 0.027 15.6 1.2 0.055 14.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4749) SNF2_N PF00176.23 CEP10281.1 - 3e-71 240.0 1.2 3e-71 240.0 1.2 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 CEP10281.1 - 1e-21 76.8 2.8 4.6e-21 74.7 2.8 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 CEP10281.1 - 3.2e-20 72.5 0.1 3.2e-19 69.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP10281.1 - 9e-11 42.1 0.1 9e-11 42.1 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit QLQ PF08880.11 CEP10281.1 - 7.1e-09 35.3 1.9 2.7e-08 33.4 1.9 2.1 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 CEP10281.1 - 1.6e-06 28.6 0.1 5.5e-06 26.9 0.1 2.0 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 CEP10281.1 - 0.0026 18.0 9.5 0.0049 17.2 6.2 3.0 2 0 0 2 2 2 1 HSA DUF1569 PF07606.11 CEP10281.1 - 0.012 15.6 0.4 0.048 13.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) Pox_A12 PF04651.13 CEP10281.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Poxvirus A12 protein Metallophos PF00149.28 CEP10282.1 - 1.7e-37 129.9 0.2 2.7e-37 129.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP10282.1 - 1.4e-05 25.4 0.1 2.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 CEP10282.1 - 0.12 12.6 1.9 0.21 11.7 1.9 1.4 1 0 0 1 1 1 0 cwf21 domain Glyco_hydro_65N PF03636.15 CEP10282.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PglZ PF08665.12 CEP10283.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 PglZ domain Vps55 PF04133.14 CEP10284.1 - 0.53 10.3 6.2 0.27 11.2 1.4 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 55 Mif2_N PF15624.6 CEP10284.1 - 2.4 8.9 4.6 5.5 7.7 4.6 1.6 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal TFIIA PF03153.13 CEP10284.1 - 6 6.7 19.5 12 5.8 19.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4238 PF14022.6 CEP10285.1 - 0.027 14.0 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Fungal_trans PF04082.18 CEP10287.1 - 1.2e-12 47.4 0.1 4.6e-12 45.5 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain PP2C PF00481.21 CEP10288.1 - 7.2e-21 75.0 0.0 6.9e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEP10288.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PHD PF00628.29 CEP10289.1 - 8.3e-07 28.8 6.7 1.7e-06 27.8 6.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 CEP10289.1 - 0.034 14.5 1.1 0.16 12.4 1.1 2.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_4 PF16866.5 CEP10289.1 - 0.56 10.3 6.2 1.7 8.8 6.2 1.9 1 0 0 1 1 1 0 PHD-finger PEX11 PF05648.14 CEP10290.1 - 3.3e-26 92.2 0.0 4.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TMEM187 PF15100.6 CEP10290.1 - 0.21 11.1 1.8 3.7 7.0 0.0 2.2 1 1 1 2 2 2 0 TMEM187 protein family PPR_2 PF13041.6 CEP10291.1 - 1.4e-43 146.8 10.2 2.7e-12 46.7 0.0 9.7 10 1 1 11 11 11 5 PPR repeat family PPR_3 PF13812.6 CEP10291.1 - 4.5e-35 119.5 4.2 6.8e-10 38.9 0.0 7.8 5 3 2 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP10291.1 - 1.4e-22 79.1 0.3 1.1e-06 28.2 0.0 8.5 9 0 0 9 9 9 4 PPR repeat PPR PF01535.20 CEP10291.1 - 4.3e-20 70.5 6.6 4.7e-06 26.5 0.0 10.1 12 0 0 12 12 12 5 PPR repeat PPR_long PF17177.4 CEP10291.1 - 2.3e-13 50.0 8.7 0.0021 17.4 0.0 4.8 3 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP RNase_P_Rpp14 PF01900.19 CEP10291.1 - 0.12 12.7 0.1 0.4 10.9 0.1 1.9 1 0 0 1 1 1 0 Rpp14/Pop5 family Mak10 PF04112.13 CEP10292.1 - 2.1e-47 160.8 1.1 1.1e-46 158.4 0.4 2.2 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3449 PF11931.8 CEP10293.1 - 1.5e-77 259.6 6.9 5.1e-77 257.8 3.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CEP10293.1 - 3e-25 88.5 6.3 3e-25 88.5 6.3 2.8 3 1 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 CEP10293.1 - 6.3e-12 45.2 0.2 1.6e-11 43.8 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 CEP10293.1 - 2.1e-08 34.3 2.4 1.8e-05 24.9 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP10293.1 - 2.2e-05 24.6 1.0 2.2e-05 24.6 1.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEP10293.1 - 0.00042 20.6 0.5 0.00042 20.6 0.5 4.0 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEP10293.1 - 0.0064 17.2 1.6 3.8 8.6 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Hormone_3 PF00159.18 CEP10293.1 - 0.046 13.8 0.6 0.16 12.1 0.2 2.2 2 0 0 2 2 2 0 Pancreatic hormone peptide DHDPS PF00701.22 CEP10295.1 - 1.6e-44 151.8 0.0 2e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Katanin_con80 PF13925.6 CEP10295.1 - 0.077 13.0 0.1 0.48 10.5 0.0 2.2 3 0 0 3 3 3 0 con80 domain of Katanin Glyco_transf_34 PF05637.12 CEP10296.1 - 5.2e-20 72.2 0.7 1.8e-19 70.5 0.7 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 CEP10296.1 - 2.3e-08 33.9 0.0 7.5e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 CEP10296.1 - 7.3e-05 22.8 0.9 0.006 16.6 0.3 2.4 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase OKR_DC_1_N PF03709.15 CEP10296.1 - 0.097 12.9 0.2 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4805 PF16063.5 CEP10296.1 - 1.1 8.5 4.0 1.7 7.9 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) RRF_GI PF12614.8 CEP10297.1 - 0.15 12.2 1.1 0.5 10.5 0.3 2.2 2 0 0 2 2 2 0 Ribosome recycling factor WD40 PF00400.32 CEP10298.1 - 2.5e-06 28.1 4.0 0.058 14.3 0.0 5.7 6 1 0 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.8 CEP10298.1 - 0.00093 17.9 0.7 0.0023 16.7 0.0 1.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CEP10298.1 - 0.00094 18.0 0.2 0.14 10.9 0.0 2.7 2 1 0 2 2 2 2 Nup133 N terminal like PQQ PF01011.21 CEP10298.1 - 0.22 11.5 0.5 3.7 7.7 0.1 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat CMAS PF02353.20 CEP10299.1 - 3.8e-66 223.2 1.4 4.6e-66 222.9 1.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CEP10299.1 - 1.9e-11 44.5 0.0 4.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP10299.1 - 6.9e-11 42.7 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP10299.1 - 1.5e-08 34.7 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP10299.1 - 2.3e-07 31.4 0.0 4.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP10299.1 - 4.2e-05 23.4 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CEP10299.1 - 0.00028 20.5 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 CEP10299.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CEP10299.1 - 0.0075 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CEP10299.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CEP10299.1 - 0.063 13.2 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 CEP10300.1 - 2.3e-58 194.1 4.7 3.1e-20 71.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 CEP10300.1 - 0.0078 16.3 0.1 0.71 10.1 0.1 2.4 2 0 0 2 2 2 1 PrcB C-terminal Wzz PF02706.15 CEP10300.1 - 0.096 13.0 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Chain length determinant protein MtrF PF09472.10 CEP10300.1 - 0.33 10.4 3.4 0.7 9.3 0.3 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) peroxidase PF00141.23 CEP10301.1 - 7e-47 160.0 0.0 1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peptidase_M48 PF01435.18 CEP10302.1 - 1.2e-17 64.3 0.0 2.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Glyco_hydro_64 PF16483.5 CEP10302.1 - 0.035 13.4 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-1,3-glucanase TPR_1 PF00515.28 CEP10302.1 - 0.1 12.4 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DELLA PF12041.8 CEP10302.1 - 0.13 12.2 0.2 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Auto_anti-p27 PF06677.12 CEP10303.1 - 3.1e-27 94.4 2.3 3.6e-14 52.6 0.4 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CxC6 PF18721.1 CEP10303.1 - 0.029 14.6 0.0 0.029 14.6 0.0 2.8 3 1 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases DUF3736 PF12540.8 CEP10303.1 - 0.053 13.6 0.3 0.053 13.6 0.3 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3736) DUF3464 PF11947.8 CEP10303.1 - 0.82 9.4 6.7 6.3 6.5 1.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 RVT_1 PF00078.27 CEP10306.1 - 4.3e-16 59.1 0.1 1.1e-15 57.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 CEP10306.1 - 0.0025 17.6 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like CagE_TrbE_VirB PF03135.14 CEP10306.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Helitron_like_N PF14214.6 CEP10308.1 - 7.4e-18 65.4 0.0 2e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RT_RNaseH PF17917.1 CEP10309.1 - 2.6e-35 120.8 0.0 4.3e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP10309.1 - 2.4e-28 98.1 0.0 4.5e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP10309.1 - 6.2e-20 71.1 0.1 1.3e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP10309.1 - 3.6e-05 23.9 0.0 6.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger SDH_C PF18317.1 CEP10310.1 - 0.044 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain rve PF00665.26 CEP10311.1 - 3.2e-05 24.1 0.0 4.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF244 PF03112.14 CEP10312.1 - 0.075 12.9 0.8 0.22 11.4 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Asp_protease_2 PF13650.6 CEP10313.1 - 1.7e-05 25.4 0.0 2.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP10313.1 - 0.00027 21.5 0.0 0.00053 20.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 CEP10313.1 - 0.03 14.1 0.2 0.058 13.2 0.1 1.5 1 1 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 CEP10313.1 - 0.051 13.4 1.4 0.079 12.7 1.4 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease NmrA PF05368.13 CEP10316.1 - 2.7e-08 33.6 0.0 9.1e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CEP10316.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding SGTA_dimer PF16546.5 CEP10317.1 - 1.8e-22 78.9 0.3 4.4e-22 77.6 0.3 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CEP10317.1 - 3.2e-12 45.7 3.1 1.9e-07 30.6 0.7 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP10317.1 - 2.1e-09 36.8 3.3 0.00015 21.6 0.7 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP10317.1 - 5.3e-08 32.7 0.4 1.1e-05 25.4 0.7 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10317.1 - 1.1e-07 31.4 5.9 1.2e-05 24.8 4.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 CEP10317.1 - 4e-07 29.7 1.2 0.00056 19.9 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP10317.1 - 1.1e-06 28.8 1.6 2.6e-06 27.6 1.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP10317.1 - 2.3e-06 27.3 1.6 7.1e-05 22.5 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP10317.1 - 2.2e-05 25.0 1.2 4e-05 24.2 1.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP10317.1 - 0.00012 21.9 0.6 0.11 12.6 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP10317.1 - 0.00022 21.8 0.1 0.46 11.4 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP10317.1 - 0.00039 20.9 1.9 0.0027 18.2 2.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 CEP10317.1 - 0.043 13.9 4.5 0.22 11.6 0.0 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 CEP10317.1 - 0.07 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat STI1 PF17830.1 CEP10317.1 - 0.16 12.0 12.7 1.8 8.5 7.7 2.5 2 0 0 2 2 2 0 STI1 domain zf-CCCH PF00642.24 CEP10318.1 - 3.7e-19 68.2 16.2 3.7e-10 39.5 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.18 CEP10318.1 - 2.2e-10 40.5 7.0 2.2e-10 40.5 7.0 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon zf_CCCH_4 PF18345.1 CEP10318.1 - 3.4e-08 33.3 14.1 0.0001 22.2 1.2 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEP10318.1 - 1.5e-06 27.8 13.3 0.0015 18.3 1.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger NUDIX PF00293.28 CEP10318.1 - 1.2e-05 25.4 0.0 5.2e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 NUDIX domain zf-CCCH_2 PF14608.6 CEP10318.1 - 4e-05 23.9 11.8 0.027 14.9 4.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CEP10318.1 - 2.6 8.8 19.8 0.071 13.8 3.0 3.2 2 1 1 3 3 3 0 Torus domain DUF4864 PF16156.5 CEP10318.1 - 6.5 7.5 7.1 1.3 9.8 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4864) Neurochondrin PF05536.11 CEP10319.1 - 5.5e-54 183.6 9.9 6.6e-54 183.3 9.9 1.1 1 0 0 1 1 1 1 Neurochondrin Utp12 PF04003.12 CEP10319.1 - 0.00027 21.2 5.4 0.85 10.0 0.0 3.5 3 0 0 3 3 3 2 Dip2/Utp12 Family DUF3514 PF12027.8 CEP10319.1 - 0.0063 16.3 0.2 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3514) Acyl_transf_3 PF01757.22 CEP10320.1 - 0.06 12.4 11.6 0.5 9.4 12.0 2.0 1 1 1 2 2 2 0 Acyltransferase family DUF4131 PF13567.6 CEP10320.1 - 8.8 5.9 12.6 2.4 7.8 3.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Aminotran_4 PF01063.19 CEP10321.1 - 1.1e-34 120.3 0.0 1.4e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TAFII28 PF04719.14 CEP10322.1 - 3e-34 117.0 0.1 7.5e-34 115.7 0.1 1.7 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Kei1 PF08552.11 CEP10322.1 - 0.019 14.9 0.3 0.019 14.9 0.3 3.3 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4229 PF14012.6 CEP10322.1 - 0.073 13.2 0.7 0.19 11.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) RasGEF PF00617.19 CEP10323.1 - 1.8e-40 139.0 0.3 6.5e-40 137.2 0.2 2.0 2 0 0 2 2 2 1 RasGEF domain Cwf_Cwc_15 PF04889.12 CEP10323.1 - 0.84 9.3 12.6 0.038 13.7 4.5 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 CEP10323.1 - 1 9.6 16.8 0.34 11.1 5.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) zf-RVT PF13966.6 CEP10324.1 - 0.0013 19.4 0.5 0.0034 18.0 0.0 1.9 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase DDE_3 PF13358.6 CEP10325.1 - 4.2e-12 46.0 0.4 1.3e-11 44.4 0.1 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HgmA PF04209.13 CEP10327.1 - 1.8e-210 699.1 0.5 2e-210 698.9 0.5 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HLH PF00010.26 CEP10328.1 - 2.1e-17 62.8 3.0 4.1e-17 61.9 3.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tubulin PF00091.25 CEP10329.1 - 1.4e-66 224.5 0.0 1.9e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP10329.1 - 7.3e-51 171.6 0.0 1.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEP10329.1 - 0.00054 19.7 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 CEP10330.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 CEP10330.1 - 8.4e-09 35.7 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Zip PF02535.22 CEP10331.1 - 1.9e-17 63.5 11.7 4.6e-17 62.2 11.7 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter TPT PF03151.16 CEP10332.1 - 7e-27 94.5 18.7 8.3e-27 94.3 18.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEP10332.1 - 6.5e-09 36.1 27.3 3.8e-05 23.9 12.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEP10332.1 - 5.8e-05 22.5 17.4 5.8e-05 22.5 17.4 1.4 1 1 0 1 1 1 1 UAA transporter family DUF1129 PF06570.11 CEP10332.1 - 3.2 7.2 7.4 1.9 7.9 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Pam17 PF08566.10 CEP10333.1 - 4.8e-58 195.6 0.1 5.9e-58 195.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 HHV-5_US34A PF17087.5 CEP10333.1 - 0.19 11.9 3.1 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus US34A protein family COPI_assoc PF08507.10 CEP10334.1 - 2.1e-25 89.3 17.0 2.9e-25 88.8 17.0 1.1 1 0 0 1 1 1 1 COPI associated protein MWFE PF15879.5 CEP10334.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2583 PF10762.9 CEP10334.1 - 1.7 9.1 7.5 2.1 8.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF2371 PF10177.9 CEP10334.1 - 2 8.6 5.4 1.8 8.7 0.2 2.3 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF5362 PF17319.2 CEP10334.1 - 3.5 7.5 17.5 3.7 7.5 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5362) LRR_6 PF13516.6 CEP10335.1 - 1.2e-05 25.0 5.8 0.055 13.6 0.0 5.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CEP10335.1 - 0.022 15.3 0.9 1.9 9.4 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat STAS_2 PF13466.6 CEP10335.1 - 0.039 14.3 0.0 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 STAS domain STAT_int PF02865.17 CEP10335.1 - 0.56 10.7 3.6 15 6.0 0.1 3.2 3 0 0 3 3 3 0 STAT protein, protein interaction domain LRR_4 PF12799.7 CEP10335.1 - 2.7 8.5 9.2 3.2 8.3 0.2 4.7 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) HsbA PF12296.8 CEP10336.1 - 5.7e-12 46.1 1.1 5.7e-12 46.1 1.1 1.6 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DAO PF01266.24 CEP10337.1 - 5.4e-44 151.2 0.0 6.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEP10337.1 - 2.7e-06 27.5 0.0 2.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP10337.1 - 1.8e-05 24.1 0.0 0.11 11.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP10337.1 - 5.6e-05 23.2 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 CEP10337.1 - 0.00062 19.0 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CEP10337.1 - 0.0085 15.3 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CEP10337.1 - 0.021 13.6 0.0 0.83 8.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 CEP10337.1 - 0.063 12.1 0.1 0.12 11.2 0.1 1.5 1 1 0 1 1 1 0 Tryptophan halogenase DLH PF01738.18 CEP10338.1 - 1.9e-22 79.9 0.0 2.2e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CEP10338.1 - 0.0028 17.3 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSP70 PF00012.20 CEP10339.1 - 4.4e-235 781.5 12.8 5e-235 781.3 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP10339.1 - 3.8e-17 62.1 2.4 3.8e-16 58.8 1.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEP10339.1 - 0.00066 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.16 CEP10339.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase eIF3_N PF09440.10 CEP10339.1 - 0.067 13.6 6.8 0.044 14.2 3.0 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Raco_middle PF17651.1 CEP10339.1 - 0.11 12.1 0.2 4.1 7.1 0.0 3.2 2 1 1 3 3 3 0 RACo middle region NDC10_II PF16787.5 CEP10340.1 - 3.9e-05 22.9 0.0 0.00023 20.3 0.0 2.1 1 1 1 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCD14 PF08704.10 CEP10341.1 - 1.5e-15 57.6 0.0 3.4e-15 56.4 0.0 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 CEP10341.1 - 1.8e-06 28.5 0.0 3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP10341.1 - 4.6e-06 26.5 0.0 6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEP10341.1 - 6.9e-05 23.8 0.0 0.00011 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEP10341.1 - 0.00029 20.7 0.0 0.00057 19.7 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CEP10341.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 CEP10342.1 - 3.7e-38 131.4 43.5 1.6e-36 126.0 24.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP10342.1 - 5.9e-07 28.7 33.9 6.3e-06 25.3 33.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_3_3 PF16083.5 CEP10342.1 - 0.84 9.8 9.3 1.8 8.8 0.9 3.0 1 1 1 2 2 2 0 LydA holin phage, holin superfamily III LCM PF04072.14 CEP10343.1 - 8.5e-24 84.5 0.0 3e-23 82.7 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase AHH PF14412.6 CEP10344.1 - 0.0035 17.4 0.0 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH TFIIA PF03153.13 CEP10344.1 - 1 9.3 21.6 1.3 9.0 21.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Seryl_tRNA_N PF02403.22 CEP10344.1 - 2.7 8.3 8.4 0.48 10.7 1.1 2.6 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Arm PF00514.23 CEP10345.1 - 1.9e-25 88.1 6.8 5.3e-07 29.5 0.0 7.8 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEP10345.1 - 1.9e-14 53.8 5.8 0.005 17.3 0.0 6.8 7 1 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 CEP10345.1 - 6.4e-12 45.7 3.7 0.00063 20.1 0.1 5.6 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CEP10345.1 - 7.2e-07 28.9 13.7 0.057 13.7 0.0 7.8 9 0 0 9 9 9 1 HEAT repeat RICTOR_V PF14668.6 CEP10345.1 - 0.0001 22.5 0.0 0.38 11.0 0.0 4.5 3 2 3 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 CEP10345.1 - 0.00017 21.7 0.9 2 8.5 0.0 3.9 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBB PF01749.20 CEP10345.1 - 0.00028 21.3 6.0 0.00056 20.3 2.9 2.8 3 0 0 3 3 3 1 Importin beta binding domain V-ATPase_H_N PF03224.14 CEP10345.1 - 0.00063 19.1 0.0 0.082 12.2 0.0 2.6 1 1 1 2 2 2 2 V-ATPase subunit H TFCD_C PF12612.8 CEP10345.1 - 0.024 14.4 0.0 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal NopRA1 PF16201.5 CEP10345.1 - 0.14 11.7 0.0 52 3.3 0.0 3.8 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Pex24p PF06398.11 CEP10346.1 - 4.8e-35 121.2 0.7 7e-35 120.7 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.22 CEP10346.1 - 5.1e-11 42.3 4.9 8.6e-11 41.6 4.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CEP10346.1 - 0.15 12.0 3.6 0.29 11.1 3.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CEP10346.1 - 0.89 9.5 4.7 2.1 8.3 4.7 1.7 1 0 0 1 1 1 0 PHD-finger Methyltransf_31 PF13847.6 CEP10347.1 - 6.2e-08 32.6 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP10347.1 - 3.9e-07 30.0 0.0 1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP10347.1 - 2.6e-05 24.8 0.0 8.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP10347.1 - 3.1e-05 24.6 0.1 0.00012 22.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP10347.1 - 0.0021 18.7 0.0 0.0075 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEP10347.1 - 0.0032 17.5 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP10347.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CEP10347.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 CEP10347.1 - 0.031 13.7 0.0 0.093 12.1 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Motile_Sperm PF00635.26 CEP10348.1 - 4.2e-24 84.5 1.2 8.2e-24 83.6 1.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CEP10348.1 - 0.0065 16.7 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEP10348.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Med30 PF11315.8 CEP10348.1 - 0.71 10.1 7.4 13 6.0 1.8 3.0 2 1 0 3 3 3 0 Mediator complex subunit 30 Bystin PF05291.11 CEP10349.1 - 3.8e-69 233.2 0.1 4.8e-69 232.9 0.1 1.1 1 0 0 1 1 1 1 Bystin SNRNP27 PF08648.12 CEP10350.1 - 6.2e-29 99.8 1.7 6.2e-29 99.8 1.7 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Presenilin PF01080.17 CEP10350.1 - 9.5 4.9 9.1 15 4.2 9.1 1.3 1 0 0 1 1 1 0 Presenilin Pro_isomerase PF00160.21 CEP10351.1 - 1.6e-48 165.0 1.3 1.7e-48 164.9 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CEP10351.1 - 1.7e-13 50.2 0.0 2.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP10351.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Aa_trans PF01490.18 CEP10352.1 - 1.1e-60 205.6 30.7 1.5e-60 205.0 30.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_25 PF13649.6 CEP10352.1 - 6.3e-07 30.0 0.0 1.3e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP10352.1 - 7.4e-07 29.7 0.0 1.8e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP10352.1 - 6.9e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP10352.1 - 2.8e-05 24.0 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP10352.1 - 2.9e-05 23.6 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 CEP10352.1 - 8.3e-05 23.3 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP10352.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cytochrom_B_C PF00032.17 CEP10352.1 - 2.8 8.3 10.6 0.54 10.6 0.5 3.5 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Arrestin_C PF02752.22 CEP10353.1 - 6.4e-06 26.7 0.1 0.0011 19.5 0.0 2.6 2 1 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP10353.1 - 0.00014 22.0 0.1 0.0022 18.1 0.1 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Carmo_coat_C PF08462.10 CEP10353.1 - 0.053 13.6 0.1 0.51 10.5 0.0 2.5 4 0 0 4 4 4 0 Carmovirus coat protein PP2C PF00481.21 CEP10354.1 - 5.7e-44 150.7 0.1 7.8e-43 147.0 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEP10354.1 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CEP10354.1 - 0.028 14.3 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Lumazine_bd_2 PF12893.7 CEP10354.1 - 0.031 15.0 0.1 0.11 13.2 0.1 1.8 2 0 0 2 2 2 0 Putative lumazine-binding DXP_synthase_N PF13292.6 CEP10355.1 - 0.0011 18.2 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MCPsignal PF00015.21 CEP10355.1 - 0.021 14.6 0.5 0.044 13.6 0.5 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LOH1CR12 PF10158.9 CEP10355.1 - 0.027 14.5 1.8 0.29 11.2 0.5 2.6 1 1 1 2 2 2 0 Tumour suppressor protein KxDL PF10241.9 CEP10355.1 - 0.048 13.9 0.3 0.048 13.9 0.3 2.5 4 0 0 4 4 3 0 Uncharacterized conserved protein Atx10homo_assoc PF09759.9 CEP10355.1 - 0.1 12.6 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain DUF2205 PF10224.9 CEP10355.1 - 0.16 12.0 5.2 0.11 12.5 1.0 2.5 2 0 0 2 2 2 0 Short coiled-coil protein NPV_P10 PF05531.12 CEP10355.1 - 0.16 12.5 6.0 0.32 11.5 0.2 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4665 PF15679.5 CEP10355.1 - 0.17 12.5 2.1 0.46 11.1 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) DUF1664 PF07889.12 CEP10355.1 - 0.18 11.9 2.0 0.71 9.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 CEP10355.1 - 0.22 11.8 8.4 0.75 10.1 8.4 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 Serine_rich PF08824.10 CEP10355.1 - 0.26 11.3 4.9 1.7 8.6 0.7 2.9 1 1 2 3 3 3 0 Serine rich protein interaction domain SlyX PF04102.12 CEP10355.1 - 0.4 11.3 7.4 0.37 11.4 0.8 2.9 3 0 0 3 3 2 0 SlyX SPX PF03105.19 CEP10355.1 - 0.96 9.3 8.9 4.3 7.2 8.9 1.8 1 1 0 1 1 1 0 SPX domain DUF3371 PF11851.8 CEP10355.1 - 2.8 9.0 8.0 1.1 10.4 4.3 2.2 3 1 0 3 3 2 0 Domain of unknown function (DUF3371) DUF2353 PF09789.9 CEP10356.1 - 0.0013 18.2 2.4 0.0024 17.3 2.4 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.21 CEP10356.1 - 0.0037 17.3 17.4 0.021 14.9 17.2 2.3 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 CEP10356.1 - 0.015 15.9 0.6 0.062 13.9 0.6 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Rootletin PF15035.6 CEP10356.1 - 0.048 13.7 7.3 0.1 12.6 1.6 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 CEP10356.1 - 2.2 8.9 6.3 0.31 11.7 1.3 2.2 2 0 0 2 2 2 0 SlyX bZIP_2 PF07716.15 CEP10356.1 - 3.3 7.9 21.7 0.61 10.2 4.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper zf-C4H2 PF10146.9 CEP10356.1 - 6.1 7.1 11.5 0.44 10.8 5.2 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein Ribophorin_II PF05817.14 CEP10357.1 - 8.7e-34 117.1 2.6 1e-33 116.9 2.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_C2 PF00648.21 CEP10358.1 - 5.6e-44 150.3 0.0 9.9e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CEP10358.1 - 1.7e-18 67.2 0.3 5.5e-05 23.4 0.3 4.8 3 1 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.18 CEP10358.1 - 2.5e-15 56.3 11.9 1.6e-07 31.3 1.8 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Aida_N PF08910.10 CEP10358.1 - 0.0076 16.6 0.1 0.022 15.1 0.1 1.8 1 0 0 1 1 1 1 Aida N-terminus ADIP PF11559.8 CEP10358.1 - 0.098 12.7 3.7 0.2 11.7 3.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_2 PF07719.17 CEP10358.1 - 0.66 10.2 9.4 0.34 11.1 0.4 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10358.1 - 1 9.3 5.3 1.7 8.6 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Use1 PF09753.9 CEP10358.1 - 4.1 7.1 8.8 12 5.6 8.6 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 GCV_H PF01597.19 CEP10359.1 - 5.1e-45 152.3 0.3 6.1e-45 152.1 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CEP10359.1 - 0.00044 20.0 1.0 0.0021 17.8 0.7 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 CEP10359.1 - 0.0011 18.8 0.2 0.0019 18.1 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 CEP10359.1 - 0.11 12.2 0.5 0.48 10.2 0.5 1.9 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 DDE_Tnp_4 PF13359.6 CEP10361.1 - 1.6e-16 60.4 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CEP10361.1 - 2.6e-06 27.2 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 CEP10361.1 - 0.00026 20.7 0.2 0.00062 19.5 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain MLVIN_C PF18697.1 CEP10362.1 - 1.5e-06 28.2 0.1 2.7e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain BAH PF01426.18 CEP10362.1 - 0.0086 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 BAH domain SAP PF02037.27 CEP10364.1 - 3.1e-14 52.3 0.8 5.6e-14 51.5 0.8 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 CEP10364.1 - 1.4e-05 24.7 0.2 4.9e-05 22.9 0.2 2.1 1 1 0 1 1 1 1 HeH/LEM domain DDE_3 PF13358.6 CEP10365.1 - 1.5e-23 83.2 0.0 4.8e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Terminase_5 PF06056.12 CEP10365.1 - 0.0045 16.8 0.4 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.6 CEP10365.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 CEP10365.1 - 0.023 14.7 0.1 0.052 13.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_17 PF12728.7 CEP10365.1 - 0.042 14.0 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 CEP10365.1 - 0.071 12.9 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Nrap_D5 PF17406.2 CEP10369.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Integrase_H2C2 PF17921.1 CEP10370.1 - 4.2e-05 23.6 0.1 8.4e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP10370.1 - 0.00046 20.3 0.3 0.0011 19.1 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 CEP10370.1 - 0.078 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase AMP-binding PF00501.28 CEP10373.1 - 2.5e-100 336.0 0.1 3.8e-100 335.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Atx10homo_assoc PF09759.9 CEP10373.1 - 1e-36 124.9 3.0 6e-36 122.4 0.1 2.5 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain AMP-binding_C PF13193.6 CEP10373.1 - 0.00039 21.3 0.1 0.0012 19.7 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Arm PF00514.23 CEP10373.1 - 0.0036 17.3 0.0 0.33 11.1 0.0 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HHH_9 PF17674.1 CEP10373.1 - 0.015 16.2 0.1 0.31 12.0 0.0 3.2 2 0 0 2 2 2 0 HHH domain Sec2p PF06428.11 CEP10374.1 - 2e-12 46.9 10.8 2e-12 46.9 10.8 3.5 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 CEP10374.1 - 0.045 11.7 15.6 0.062 11.2 15.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 CEP10375.1 - 2.8e-08 34.1 7.9 2.8e-08 34.1 7.9 2.6 2 1 1 3 3 3 1 Centromere protein H (CENP-H) DEAD_assoc PF08494.11 CEP10375.1 - 0.038 13.8 0.8 0.062 13.1 0.8 1.3 1 0 0 1 1 1 0 DEAD/H associated DivIC PF04977.15 CEP10375.1 - 0.041 13.7 2.0 0.041 13.7 2.0 3.3 2 1 1 3 3 3 0 Septum formation initiator Pribosyltran_N PF13793.6 CEP10375.1 - 0.05 13.6 0.8 0.15 12.0 0.8 1.8 1 1 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase DUF547 PF04784.14 CEP10375.1 - 0.068 13.2 2.3 0.11 12.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF547 ZnuA PF01297.17 CEP10375.1 - 0.2 11.0 3.5 0.17 11.3 2.1 1.6 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic AAA-ATPase_like PF09820.9 CEP10375.1 - 0.66 9.4 8.2 0.29 10.5 5.0 1.8 1 1 1 2 2 2 0 Predicted AAA-ATPase DUF4763 PF15960.5 CEP10375.1 - 0.73 9.1 15.8 0.026 13.9 4.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) TERB2 PF15101.6 CEP10375.1 - 2.1 8.4 9.2 0.16 12.0 1.1 2.1 1 1 1 2 2 2 0 Telomere-associated protein TERB2 SlyX PF04102.12 CEP10375.1 - 4 8.1 12.5 14 6.4 2.6 3.4 2 1 0 3 3 3 0 SlyX DUF16 PF01519.16 CEP10375.1 - 7.7 7.1 19.3 5 7.7 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fe_hyd_lg_C PF02906.14 CEP10377.1 - 5.8e-75 252.1 0.1 2.7e-62 210.6 0.0 2.4 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain DTW PF03942.15 CEP10377.1 - 1.9e-24 86.5 0.2 4.6e-24 85.2 0.0 1.7 2 0 0 2 2 2 1 DTW domain Fe_hyd_SSU PF02256.17 CEP10377.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit DUF2238 PF09997.9 CEP10377.1 - 0.035 13.9 0.2 0.081 12.7 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) GCHY-1 PF02649.14 CEP10378.1 - 0.024 14.2 0.2 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Type I GTP cyclohydrolase folE2 DUF713 PF05218.14 CEP10378.1 - 0.069 12.9 2.4 0.25 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF713) HTH_Crp_2 PF13545.6 CEP10378.1 - 0.13 12.3 0.4 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF3038 PF11237.8 CEP10379.1 - 0.013 15.5 0.1 0.015 15.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Pex14_N PF04695.13 CEP10379.1 - 0.12 13.0 17.8 0.14 12.8 17.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM131 PF15010.6 CEP10379.1 - 0.36 10.7 1.8 0.4 10.5 1.8 1.1 1 0 0 1 1 1 0 Putative cell signalling CYSTM PF12734.7 CEP10379.1 - 0.45 10.9 80.0 1.8e+04 -22.2 80.0 4.7 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 CEP10379.1 - 7.5 6.5 22.2 9.1 6.2 22.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pox_MCEL PF03291.16 CEP10380.1 - 2.7e-88 296.3 0.1 4.9e-88 295.4 0.1 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CEP10380.1 - 6.5e-14 52.4 0.0 1.9e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP10380.1 - 1.1e-07 32.3 0.0 4.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP10380.1 - 4.6e-07 30.5 0.0 9.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP10380.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP10380.1 - 1.7e-06 27.9 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP10380.1 - 0.00075 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 CEP10380.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MetW PF07021.12 CEP10380.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PrmA PF06325.13 CEP10380.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CEP10380.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Asp PF00026.23 CEP10381.1 - 1.3e-110 369.7 0.0 1.6e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP10381.1 - 3.2e-14 53.6 0.7 3.7e-12 46.8 0.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP10381.1 - 0.00087 19.1 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP10381.1 - 0.0012 19.5 0.0 0.93 10.2 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease DUF2433 PF10360.9 CEP10382.1 - 4.4e-44 149.5 0.8 9.1e-44 148.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2407_C PF13373.6 CEP10382.1 - 6.3e-10 39.4 1.2 1.1e-09 38.7 0.3 1.8 2 0 0 2 2 2 1 DUF2407 C-terminal domain RRM_1 PF00076.22 CEP10382.1 - 8.2e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2407 PF10302.9 CEP10382.1 - 6.1e-07 29.9 0.1 2.3e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CEP10382.1 - 9.3e-05 22.1 0.1 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1980 PF09323.10 CEP10382.1 - 0.32 10.9 1.8 0.55 10.1 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) VHS PF00790.19 CEP10383.1 - 4.6e-42 143.2 0.5 1.3e-41 141.7 0.0 2.1 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CEP10383.1 - 1.7e-23 83.0 1.7 1.7e-23 83.0 1.7 2.8 3 1 0 3 3 3 1 Adaptin C-terminal domain GAT PF03127.14 CEP10383.1 - 1.4e-19 70.2 2.5 2.7e-19 69.3 1.2 2.3 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 CEP10383.1 - 0.00011 21.7 0.1 0.00011 21.7 0.1 2.8 3 0 0 3 3 3 1 GGA N-GAT domain Luteo_P1-P2 PF08467.10 CEP10383.1 - 0.032 13.5 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Ndc1_Nup PF09531.10 CEP10383.1 - 6.6 5.3 8.8 9.4 4.8 8.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 CEP10384.1 - 1e-25 90.7 0.0 1e-25 90.7 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10384.1 - 1.8e-17 63.5 0.1 3e-17 62.8 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP10384.1 - 5.5e-10 38.6 0.1 1.1e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP10384.1 - 0.0015 18.5 0.1 0.0043 17.0 0.1 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CEP10384.1 - 0.029 13.4 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L2_C PF03947.18 CEP10385.1 - 4.1e-46 156.3 3.6 4.1e-46 156.3 3.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEP10385.1 - 7.8e-16 57.8 0.1 2e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DJ-1_PfpI PF01965.24 CEP10386.1 - 1.2e-43 148.7 0.3 1.5e-43 148.5 0.3 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CEP10386.1 - 5.9e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 CEP10386.1 - 0.00026 20.7 0.1 0.00038 20.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase PF00117.28 CEP10386.1 - 0.0034 17.2 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CEP10386.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain VWA PF00092.28 CEP10386.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain SNO PF01174.19 CEP10386.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Sld5 PF05916.11 CEP10387.1 - 0.007 16.8 0.4 0.007 16.8 0.4 2.0 2 1 0 2 2 2 1 GINS complex protein Aminotran_5 PF00266.19 CEP10388.1 - 1.3e-11 44.0 0.0 1.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.18 CEP10389.1 - 5.2e-11 42.5 11.4 8.3e-11 41.8 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.24 CEP10389.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 PX domain Muskelin_N PF06588.11 CEP10390.1 - 1.2e-70 237.4 0.9 1.2e-70 237.4 0.9 1.7 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_4 PF13418.6 CEP10390.1 - 2e-21 75.8 4.7 1.9e-05 24.5 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP10390.1 - 5.6e-21 74.0 6.4 1.3e-05 25.3 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CEP10390.1 - 1.5e-20 73.0 10.0 1e-09 38.4 0.1 6.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP10390.1 - 9.3e-19 66.8 14.7 7.7e-08 31.8 0.2 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CEP10390.1 - 4.5e-17 61.3 6.2 2.5e-05 24.1 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CEP10390.1 - 2.4e-16 59.3 2.8 0.0022 18.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif F5_F8_type_C PF00754.25 CEP10390.1 - 4.4e-05 23.6 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain UPF0016 PF01169.19 CEP10391.1 - 2.3e-42 143.2 19.7 3.9e-21 75.2 4.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 CEP10391.1 - 0.0003 20.5 7.3 0.023 14.4 0.0 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Mntp PF02659.15 CEP10391.1 - 0.00086 19.1 6.1 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 Putative manganese efflux pump DUF3341 PF11821.8 CEP10391.1 - 0.47 10.1 8.7 0.04 13.6 2.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) WD40 PF00400.32 CEP10392.1 - 1.1e-10 41.9 18.3 0.00026 21.7 0.2 5.8 6 0 0 6 6 5 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CEP10392.1 - 9.9e-10 38.1 13.4 9.9e-10 38.1 13.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP10392.1 - 2.1e-09 37.1 9.2 2.1e-09 37.1 9.2 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 CEP10392.1 - 4.5e-09 36.5 0.2 0.019 15.2 0.0 3.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 CEP10392.1 - 1.7e-08 34.4 6.8 1.7e-08 34.4 6.8 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEP10392.1 - 2.5e-08 34.1 12.0 2.5e-08 34.1 12.0 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CEP10392.1 - 4.5e-07 29.6 12.9 4.5e-07 29.6 12.9 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP10392.1 - 2e-06 27.7 11.7 2e-06 27.7 11.7 3.0 3 1 0 3 3 2 1 zinc-RING finger domain U-box PF04564.15 CEP10392.1 - 1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 CEP10392.1 - 2.1e-05 24.3 12.0 2.1e-05 24.3 12.0 2.6 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP10392.1 - 2.2e-05 24.6 7.7 2.2e-05 24.6 7.7 3.1 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CEP10392.1 - 9.8e-05 22.4 11.8 9.8e-05 22.4 11.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CEP10392.1 - 0.00039 20.2 3.8 0.00055 19.8 2.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CEP10392.1 - 0.0013 18.8 6.0 0.0039 17.3 6.0 1.9 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CEP10392.1 - 0.0042 16.9 7.0 0.024 14.4 7.3 2.3 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 CEP10392.1 - 0.028 14.4 7.0 0.076 13.0 7.0 1.8 1 0 0 1 1 1 0 zinc-ribbons zf-Nse PF11789.8 CEP10392.1 - 0.041 13.7 6.0 0.12 12.3 6.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nnf1 PF03980.14 CEP10392.1 - 0.24 11.8 3.6 0.86 10.0 3.6 2.0 1 0 0 1 1 1 0 Nnf1 zf-ANAPC11 PF12861.7 CEP10392.1 - 0.29 11.2 8.3 0.068 13.2 3.9 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 CEP10392.1 - 0.62 9.8 4.4 22 4.9 1.0 3.3 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-P11 PF03854.14 CEP10392.1 - 6.4 6.5 10.1 19 5.0 10.1 1.8 1 1 0 1 1 1 0 P-11 zinc finger Histidinol_dh PF00815.20 CEP10394.1 - 1.1e-164 548.3 1.3 1.9e-164 547.6 1.3 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CEP10394.1 - 1.6e-23 82.3 0.1 4.1e-23 81.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CEP10394.1 - 4.3e-15 55.9 1.4 7.7e-15 55.1 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 CEP10394.1 - 0.015 15.5 1.0 0.062 13.5 0.2 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain DDE_3 PF13358.6 CEP10395.1 - 1.6e-11 44.2 0.5 2.9e-11 43.3 0.3 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3543 PF12063.8 CEP10395.1 - 0.063 12.6 0.1 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) zf-RVT PF13966.6 CEP10396.1 - 2.9e-06 27.9 0.3 6.1e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-RVT PF13966.6 CEP10397.1 - 0.0017 19.0 1.1 0.0017 19.0 1.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Popeye PF04831.13 CEP10397.1 - 2.6 8.2 7.2 3 8.0 0.8 2.3 2 0 0 2 2 2 0 Popeye protein conserved region HTH_23 PF13384.6 CEP10398.1 - 0.00044 20.0 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain FeoC PF09012.10 CEP10398.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 FeoC like transcriptional regulator PAX PF00292.18 CEP10398.1 - 0.0032 17.4 0.0 0.0051 16.7 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_Crp_2 PF13545.6 CEP10398.1 - 0.0052 16.7 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CEP10398.1 - 0.0065 15.9 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 CEP10398.1 - 0.024 14.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.6 CEP10398.1 - 0.024 14.8 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Bot1p PF12298.8 CEP10398.1 - 0.04 14.1 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein CENP-B_N PF04218.13 CEP10398.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Integrase_H2C2 PF17921.1 CEP10401.1 - 1.8e-12 47.2 0.4 3.9e-12 46.1 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP10401.1 - 1.6e-11 43.9 2.2 1e-10 41.3 0.6 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP10401.1 - 3.1e-09 37.0 0.0 6.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP10401.1 - 0.00017 21.7 0.3 0.00041 20.5 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Tudor-knot PF11717.8 CEP10401.1 - 0.07 13.0 0.4 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Neuromodulin_N PF10580.9 CEP10401.1 - 3 7.7 4.6 2.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Gap junction protein N-terminal region Asp_protease_2 PF13650.6 CEP10402.1 - 2.3e-05 24.9 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP10402.1 - 2.6e-05 24.7 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease BNIP2 PF12496.8 CEP10402.1 - 0.057 13.9 0.7 0.083 13.3 0.7 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RVP_2 PF08284.11 CEP10402.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 CEP10403.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CNOT1_TTP_bind PF16417.5 CEP10403.1 - 0.023 13.9 0.3 0.053 12.7 0.3 1.5 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain DP-EP PF08985.11 CEP10404.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.5 2 0 0 2 2 2 0 DP-EP family Frankia_peptide PF14407.6 CEP10404.1 - 0.1 12.6 0.1 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Helitron_like_N PF14214.6 CEP10405.1 - 4.3e-24 85.8 0.0 4.9e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.27 CEP10406.1 - 3.1e-06 26.9 0.1 8.4e-06 25.5 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_23 PF13384.6 CEP10407.1 - 0.012 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 CEP10407.1 - 0.041 13.9 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CEP10407.1 - 0.048 14.0 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.6 CEP10407.1 - 0.073 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 CEP10407.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 CEP10407.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain ADH_zinc_N PF00107.26 CEP10409.1 - 8.5e-22 77.5 0.3 1.4e-21 76.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP10409.1 - 1.8e-09 38.7 0.1 3.9e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP10409.1 - 7e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CEP10409.1 - 0.0076 15.7 0.3 0.014 14.8 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 CEP10409.1 - 0.0081 15.5 0.3 0.014 14.7 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_C13 PF01650.18 CEP10409.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase C13 family NAD_binding_7 PF13241.6 CEP10409.1 - 0.081 13.4 0.1 0.14 12.6 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ADH_N_2 PF16884.5 CEP10409.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Tsp45I PF06300.12 CEP10410.1 - 0.0035 16.9 0.3 1.6 8.2 0.1 2.1 2 0 0 2 2 2 2 Tsp45I type II restriction enzyme RT_RNaseH PF17917.1 CEP10414.1 - 1.2e-18 67.3 0.3 2.5e-18 66.3 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP10414.1 - 3.2e-12 46.4 0.1 7.2e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEP10414.1 - 3.3e-05 23.8 0.0 8.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEP10414.1 - 0.0032 17.7 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger DUF1248 PF06852.12 CEP10414.1 - 0.025 14.0 0.2 0.046 13.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) RVT_1 PF00078.27 CEP10415.1 - 5.5e-26 91.5 0.4 1.1e-25 90.5 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP10415.1 - 0.00028 20.9 0.2 0.0015 18.5 0.0 2.3 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 CEP10415.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Phage_int_SAM_4 PF13495.6 CEP10416.1 - 4.2e-05 23.9 0.1 0.00085 19.8 0.1 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain RNase_H PF00075.24 CEP10416.1 - 0.0021 18.3 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 RNase H Phage_int_SAM_1 PF02899.17 CEP10416.1 - 0.0068 16.7 0.2 0.015 15.6 0.2 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DNA_pol_viral_C PF00336.18 CEP10416.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Glyco_hydro_18 PF00704.28 CEP10418.1 - 2.5e-62 211.4 0.9 2.9e-62 211.2 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 CEP10419.1 - 9.7e-49 166.1 0.0 8.1e-39 133.6 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain MFS_1_like PF12832.7 CEP10419.1 - 1.1e-29 103.5 6.6 1.8e-29 102.8 6.6 1.2 1 0 0 1 1 1 1 MFS_1 like family Pkinase_Tyr PF07714.17 CEP10419.1 - 3.9e-17 62.4 0.1 2e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase MFS_1 PF07690.16 CEP10419.1 - 5.4e-08 32.1 17.5 3.5e-06 26.2 17.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 CEP10419.1 - 0.061 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PIF PF05092.12 CEP10419.1 - 0.09 11.5 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 Per os infectivity APH PF01636.23 CEP10419.1 - 0.19 11.6 0.2 0.48 10.3 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-H2C2_2 PF13465.6 CEP10420.1 - 5.7e-11 42.3 8.1 0.00018 21.8 0.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP10420.1 - 4.1e-07 30.1 17.2 0.00035 20.9 1.8 3.0 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP10420.1 - 3.8e-05 24.2 15.4 0.0036 18.0 1.4 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP10420.1 - 0.00068 19.6 1.2 0.00068 19.6 1.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP10420.1 - 0.0041 17.4 4.3 0.09 13.1 0.4 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 CEP10420.1 - 0.0096 15.8 2.3 0.62 10.0 0.7 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type MCM_OB PF17207.3 CEP10420.1 - 0.069 13.0 1.2 0.12 12.2 1.2 1.4 1 0 0 1 1 1 0 MCM OB domain zf-C2H2_11 PF16622.5 CEP10420.1 - 0.098 12.4 7.9 0.41 10.4 0.6 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 CEP10420.1 - 0.13 12.7 1.5 0.91 10.0 0.3 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-HC5HC2H PF13771.6 CEP10420.1 - 0.15 12.4 2.5 0.38 11.0 2.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_SprT PF17283.2 CEP10420.1 - 0.49 10.3 5.0 0.38 10.7 1.7 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Lung_7-TM_R PF06814.13 CEP10421.1 - 2.8e-64 217.2 22.4 3.6e-64 216.8 22.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 CEP10421.1 - 0.32 10.4 29.7 0.04 13.3 22.9 2.5 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain DUF1028 PF06267.12 CEP10421.1 - 0.9 9.3 2.1 1.3 8.8 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF1028) DUF3671 PF12420.8 CEP10421.1 - 7.1 6.7 11.7 0.076 13.1 1.6 2.8 3 2 0 3 3 3 0 Protein of unknown function Ribosomal_L35Ae PF01247.18 CEP10422.1 - 2.1e-42 143.2 0.9 2.4e-42 143.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CEP10422.1 - 0.00093 19.4 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 CEP10422.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Aldo_ket_red PF00248.21 CEP10423.1 - 5.8e-43 147.2 0.0 7.4e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NifU_N PF01592.16 CEP10424.1 - 5.5e-49 165.6 0.3 1.8e-47 160.7 0.1 2.2 1 1 1 2 2 2 2 NifU-like N terminal domain EamA PF00892.20 CEP10424.1 - 3.4e-06 27.3 21.1 0.00049 20.3 3.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CEP10424.1 - 0.00036 20.0 6.8 0.00055 19.4 6.8 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family CRT-like PF08627.10 CEP10424.1 - 0.09 11.7 11.0 0.027 13.5 4.7 2.2 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Aldo_ket_red PF00248.21 CEP10425.1 - 2.2e-30 105.9 0.1 1.6e-24 86.7 0.1 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family MBG PF17883.1 CEP10425.1 - 0.0058 17.2 0.1 0.011 16.3 0.1 1.4 1 0 0 1 1 1 1 MBG domain CAP59_mtransfer PF11735.8 CEP10425.1 - 0.095 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF325 PF03804.13 CEP10425.1 - 0.11 12.6 0.3 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Viral proteins of unknown function Lipase_GDSL PF00657.22 CEP10426.1 - 1.1e-10 41.8 0.1 1.5e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP10426.1 - 2.1e-05 25.0 0.1 3.2e-05 24.4 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HNH PF01844.23 CEP10427.1 - 0.00028 21.0 0.3 0.00028 21.0 0.3 2.5 3 1 0 3 3 3 1 HNH endonuclease HNH_2 PF13391.6 CEP10427.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease RA PF00788.23 CEP10428.1 - 3.2e-10 40.5 0.0 8.4e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CEP10428.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 SH3 domain TUG-UBL1 PF11470.8 CEP10428.1 - 0.061 13.6 0.1 6.6 7.0 0.0 3.0 2 0 0 2 2 2 0 TUG ubiquitin-like domain Connexin PF00029.19 CEP10429.1 - 4.3e-05 23.4 5.1 4.3e-05 23.4 5.1 2.1 1 1 1 2 2 2 1 Connexin Raftlin PF15250.6 CEP10429.1 - 0.048 12.4 16.2 0.06 12.1 16.2 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 CEP10429.1 - 0.1 11.4 20.7 0.11 11.2 20.7 1.1 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 CEP10429.1 - 0.1 12.7 21.1 0.14 12.3 21.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SLC12 PF03522.15 CEP10429.1 - 0.18 10.8 23.4 0.23 10.4 23.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 CEP10429.1 - 0.84 8.7 21.2 0.95 8.5 21.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CEP10429.1 - 0.86 7.8 27.8 1.1 7.5 27.8 1.1 1 0 0 1 1 1 0 CDC45-like protein O-antigen_lig PF13425.6 CEP10429.1 - 1.3 7.8 11.8 1.8 7.2 11.8 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Endostatin PF06482.11 CEP10429.1 - 1.8 7.9 10.5 2.4 7.5 10.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Dapper PF15268.6 CEP10429.1 - 1.9 7.2 24.9 2.2 7.0 24.9 1.0 1 0 0 1 1 1 0 Dapper Hydin_ADK PF17213.3 CEP10429.1 - 1.9 8.7 12.7 2.6 8.3 12.7 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 CEP10429.1 - 4.2 6.0 26.8 5.3 5.7 26.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 R_equi_Vir PF05526.11 CEP10429.1 - 4.7 7.0 5.6 12 5.7 0.1 2.2 1 1 1 2 2 2 0 Rhodococcus equi virulence-associated protein AAA_11 PF13086.6 CEP10429.1 - 5.1 6.8 21.6 8.4 6.1 21.6 1.4 1 0 0 1 1 1 0 AAA domain SOBP PF15279.6 CEP10429.1 - 7.8 7.0 14.6 9.6 6.7 14.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MDM10 PF12519.8 CEP10429.1 - 9.8 4.9 19.6 12 4.6 19.6 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Mt_ATP-synt_B PF05405.14 CEP10430.1 - 1.5e-47 161.2 8.2 2.2e-47 160.7 8.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 CEP10430.1 - 0.0079 16.5 0.5 0.021 15.1 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5623) DUF1539 PF07560.11 CEP10430.1 - 0.028 14.5 2.3 0.051 13.7 2.3 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) COMPASS-Shg1 PF05205.12 CEP10430.1 - 1.3 9.7 7.6 13 6.6 1.9 2.5 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 WD40 PF00400.32 CEP10431.1 - 1.5e-37 126.9 26.4 1.2e-08 35.4 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP10431.1 - 1e-16 61.0 2.2 0.0019 18.5 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP10431.1 - 4.5e-11 42.6 0.0 5.5e-05 22.6 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 CEP10431.1 - 1.1e-07 31.9 0.1 0.0018 18.2 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEP10431.1 - 1.2e-06 27.5 2.4 0.02 13.5 0.1 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP10431.1 - 0.00036 19.6 6.5 0.062 12.3 0.0 3.9 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DJ-1_PfpI PF01965.24 CEP10431.1 - 0.055 13.3 0.4 0.59 9.9 0.2 2.5 2 1 0 2 2 2 0 DJ-1/PfpI family DUF1513 PF07433.11 CEP10431.1 - 0.16 11.1 0.2 25 3.8 0.0 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1513) Pkinase PF00069.25 CEP10432.1 - 5.6e-26 91.5 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.22 CEP10432.1 - 4e-19 69.1 0.0 6.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.17 CEP10432.1 - 1.1e-12 47.9 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP10432.1 - 4.2e-09 35.7 0.3 9e-09 34.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP10432.1 - 0.001 19.1 1.7 0.0086 16.0 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Complex1_LYR_2 PF13233.6 CEP10433.1 - 3.1e-25 88.7 0.0 4.8e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CEP10433.1 - 2.4e-12 46.7 0.0 3.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) T4SS_TraI PF16932.5 CEP10433.1 - 0.028 13.6 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer Complex1_LYR_1 PF13232.6 CEP10433.1 - 0.045 14.4 0.0 0.069 13.8 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like PGM_PMM_I PF02878.16 CEP10434.1 - 4e-41 139.9 0.1 1.3e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CEP10434.1 - 4.2e-24 85.1 0.0 1.3e-23 83.5 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CEP10434.1 - 4.1e-12 46.3 0.1 7.3e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CEP10434.1 - 5.6e-05 23.2 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pex24p PF06398.11 CEP10435.1 - 7.8e-18 64.6 1.9 7.8e-18 64.6 1.9 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_1 PF00130.22 CEP10435.1 - 1.5e-11 44.0 13.5 3.3e-11 42.9 13.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CEP10435.1 - 0.033 14.5 7.8 0.07 13.5 7.8 1.5 1 0 0 1 1 1 0 C1 domain adh_short PF00106.25 CEP10436.1 - 2.5e-51 173.9 0.1 2.5e-51 173.9 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP10436.1 - 4.5e-39 134.4 2.5 6.9e-39 133.8 0.1 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP10436.1 - 3e-11 43.6 0.2 3e-11 43.6 0.2 2.6 3 0 0 3 3 3 1 KR domain OmpH PF03938.14 CEP10436.1 - 0.016 15.5 0.1 0.016 15.5 0.1 7.2 2 2 4 6 6 6 0 Outer membrane protein (OmpH-like) Epimerase PF01370.21 CEP10436.1 - 0.035 13.6 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family STAG PF08514.11 CEP10437.1 - 2.3e-37 127.4 8.3 5.8e-37 126.1 3.9 3.6 3 0 0 3 3 3 1 STAG domain HEAT PF02985.22 CEP10437.1 - 0.011 15.9 0.7 26 5.4 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat SPATA3 PF15662.5 CEP10437.1 - 9 6.9 7.9 19 5.8 5.4 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Pex14_N PF04695.13 CEP10440.1 - 1.3e-28 100.7 3.0 1.3e-28 100.7 3.0 4.4 3 2 1 4 4 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 CEP10440.1 - 3.5e-05 23.8 0.7 8.7e-05 22.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF812 PF05667.11 CEP10440.1 - 0.00066 18.7 0.8 0.0008 18.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 CEP10440.1 - 0.0014 18.7 4.6 0.0014 18.7 4.6 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 CEP10440.1 - 0.0033 17.6 15.1 0.097 12.9 1.0 3.4 2 1 1 3 3 3 2 Haemolysin XhlA LXG PF04740.12 CEP10440.1 - 0.015 15.0 9.5 0.018 14.8 8.4 1.7 1 1 0 1 1 1 0 LXG domain of WXG superfamily Exog_C PF18026.1 CEP10440.1 - 0.026 14.6 0.3 0.086 12.9 0.3 1.8 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain UPF0242 PF06785.11 CEP10440.1 - 0.053 13.6 7.1 0.09 12.9 7.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 CEP10440.1 - 0.077 14.1 0.3 0.41 11.8 0.0 2.3 2 0 0 2 2 1 0 Family of unknown function (DUF5320) CdvA PF18822.1 CEP10440.1 - 0.1 12.4 9.7 0.53 10.1 7.0 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Spc7 PF08317.11 CEP10440.1 - 0.12 11.2 10.2 0.25 10.2 10.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Tektin PF03148.14 CEP10440.1 - 0.17 10.6 10.5 0.028 13.2 5.1 1.9 1 1 1 2 2 2 0 Tektin family Caskin-tail PF16632.5 CEP10440.1 - 0.31 11.5 7.2 0.76 10.2 3.1 3.0 2 1 0 2 2 2 0 C-terminal region of Caskin TMPIT PF07851.13 CEP10440.1 - 0.37 10.0 6.3 0.56 9.4 6.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Prominin PF05478.11 CEP10440.1 - 0.44 8.5 6.0 0.58 8.0 6.0 1.1 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 CEP10440.1 - 0.66 10.0 14.7 0.053 13.5 7.7 2.5 2 1 0 2 2 2 0 Laminin Domain II SKA2 PF16740.5 CEP10440.1 - 0.78 9.5 8.8 3.9 7.3 0.7 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ATPase PF06745.13 CEP10440.1 - 0.8 9.0 3.5 1.4 8.2 3.5 1.4 1 0 0 1 1 1 0 KaiC Flagellar_rod PF05149.12 CEP10440.1 - 0.92 8.9 10.3 2.7 7.4 4.5 2.1 1 1 1 2 2 2 0 Paraflagellar rod protein APG6_N PF17675.1 CEP10440.1 - 1.1 9.8 15.7 53 4.3 3.0 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 CEP10440.1 - 1.2 8.5 13.5 1.6 8.0 10.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 CEP10440.1 - 1.7 9.1 8.2 0.099 13.0 1.6 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TolA_bind_tri PF16331.5 CEP10440.1 - 1.7 8.8 6.1 1.6 8.9 0.3 2.9 2 1 0 3 3 3 0 TolA binding protein trimerisation DUF4200 PF13863.6 CEP10440.1 - 1.7 9.0 11.7 8.2 6.9 11.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 CEP10440.1 - 2.6 8.3 13.8 0.17 12.1 7.6 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein DUF948 PF06103.11 CEP10440.1 - 2.7 8.3 10.8 0.38 11.0 3.4 2.7 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 CEP10440.1 - 2.8 7.9 6.4 2.8 7.9 3.3 2.3 1 1 2 3 3 3 0 Sec20 Fmp27_WPPW PF10359.9 CEP10440.1 - 4.8 5.9 11.6 11 4.8 11.6 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF16 PF01519.16 CEP10440.1 - 5.5 7.5 15.4 5.4 7.6 10.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 CEP10440.1 - 5.9 7.1 9.7 6.4 7.0 0.8 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 CEP10440.1 - 7.8 6.7 16.0 0.45 10.7 10.8 1.6 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 CEP10440.1 - 8 6.4 12.0 7 6.6 0.6 3.1 1 1 1 3 3 3 0 Prefoldin subunit DUF1043 PF06295.12 CEP10440.1 - 8.1 6.5 9.0 0.52 10.3 3.5 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1043) E2F_CC-MB PF16421.5 CEP10440.1 - 9.1 6.7 8.4 6.4 7.2 2.1 2.4 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain YabA PF06156.13 CEP10440.1 - 9.5 6.9 9.6 4.9 7.9 3.1 2.4 1 1 1 2 2 2 0 Initiation control protein YabA MOZ_SAS PF01853.18 CEP10441.1 - 7.2e-51 172.4 0.2 4.8e-47 159.9 0.1 2.2 1 1 1 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CEP10441.1 - 1.5e-19 69.3 0.8 3.1e-19 68.3 0.8 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CEP10441.1 - 3.7e-05 24.1 0.0 7.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP10441.1 - 0.00031 20.9 0.0 0.0007 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEP10441.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein RAG1 PF12940.7 CEP10441.1 - 0.047 11.8 0.0 0.065 11.3 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Actin PF00022.19 CEP10442.1 - 4.4e-61 206.7 0.0 1.8e-31 109.2 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CEP10442.1 - 0.017 14.0 0.0 0.38 9.5 0.0 2.5 2 0 0 2 2 2 0 MreB/Mbl protein DUF2589 PF11655.8 CEP10442.1 - 0.55 10.5 4.8 7.5 6.9 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) NTP_transf_4 PF13562.6 CEP10442.1 - 0.72 10.1 3.9 0.16 12.2 0.3 1.8 2 0 0 2 2 2 0 Sugar nucleotidyl transferase ATG13 PF10033.9 CEP10443.1 - 2.4e-67 227.2 0.2 2.4e-67 227.2 0.2 1.9 2 0 0 2 2 2 1 Autophagy-related protein 13 Spt20 PF12090.8 CEP10443.1 - 0.037 13.6 28.5 0.056 13.0 1.4 3.2 3 0 0 3 3 3 0 Spt20 family DUF4770 PF15994.5 CEP10443.1 - 9.1 6.5 13.6 6.5 7.0 4.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) zf-Tim10_DDP PF02953.15 CEP10444.1 - 5.8e-17 61.1 1.8 8.4e-17 60.6 1.8 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CEP10444.1 - 0.02 14.6 3.5 0.62 9.8 2.9 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Polysacc_deac_1 PF01522.21 CEP10445.1 - 5.3e-30 103.9 0.1 1.2e-29 102.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP10445.1 - 0.19 10.9 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NPR2 PF06218.11 CEP10446.1 - 1.7e-111 373.1 7.7 9e-87 291.6 9.7 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 CEP10446.1 - 0.12 12.9 0.6 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNase_H2-Ydr279 PF09468.10 CEP10447.1 - 6.1e-09 36.3 1.5 1e-08 35.5 1.5 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CEP10447.1 - 0.0002 21.5 0.0 0.0005 20.3 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Pro_isomerase PF00160.21 CEP10449.1 - 6.7e-47 159.7 0.5 7.5e-47 159.5 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Suc_Fer-like PF06999.12 CEP10450.1 - 2.2e-53 181.0 0.0 7.7e-53 179.3 0.0 2.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pterin_4a PF01329.19 CEP10450.1 - 3.5e-28 97.6 0.0 3.5e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase DNA_pol_A_exo1 PF01612.20 CEP10450.1 - 2.2e-11 43.8 0.0 5.9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_3 PF13920.6 CEP10450.1 - 0.00084 19.2 1.8 0.00084 19.2 1.8 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 CEP10450.1 - 0.022 14.7 1.5 8.7 6.3 0.0 3.0 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding TFIIA PF03153.13 CEP10450.1 - 0.058 13.4 36.3 0.12 12.4 36.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ezh2_MCSS PF18600.1 CEP10451.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 MCSS domain Pro_isomerase PF00160.21 CEP10452.1 - 6.2e-35 120.8 0.0 5.5e-34 117.7 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med25_VWA PF11265.8 CEP10453.1 - 1.5e-28 100.1 0.0 3.7e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A 2-oxoacid_dh PF00198.23 CEP10454.1 - 7.7e-72 241.5 0.0 1.1e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEP10454.1 - 4.9e-17 61.5 0.1 1.1e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEP10454.1 - 4.5e-10 39.7 0.1 1.7e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain Helicase_C_2 PF13307.6 CEP10455.1 - 8.6e-53 179.0 0.1 3.2e-52 177.1 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CEP10455.1 - 5.7e-49 166.1 0.4 1.3e-48 165.0 0.4 1.6 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CEP10455.1 - 2e-06 27.7 1.3 0.0015 18.3 0.0 3.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP10455.1 - 2.9e-05 24.1 1.2 0.0017 18.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HBB PF06777.11 CEP10455.1 - 0.0013 18.5 0.0 0.0046 16.7 0.0 1.9 1 0 0 1 1 1 1 Helical and beta-bridge domain PhoH PF02562.16 CEP10455.1 - 0.0046 16.4 0.2 2.9 7.3 0.1 2.8 2 1 0 2 2 2 2 PhoH-like protein BLM10_N PF16547.5 CEP10455.1 - 0.012 15.9 0.0 0.051 13.9 0.0 2.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal DUF4748 PF15932.5 CEP10455.1 - 0.2 11.4 1.2 0.63 9.8 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Sybindin PF04099.12 CEP10456.1 - 2.2e-23 82.7 0.2 3.4e-23 82.2 0.2 1.2 1 0 0 1 1 1 1 Sybindin-like family Sod_Cu PF00080.20 CEP10456.1 - 0.0046 17.1 0.0 0.0085 16.3 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) L51_S25_CI-B8 PF05047.16 CEP10457.1 - 2.2e-11 43.5 0.1 3.8e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RRM_1 PF00076.22 CEP10458.1 - 9.4e-75 246.4 3.1 4.1e-17 61.8 0.0 6.7 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CEP10458.1 - 5.6e-05 23.1 0.0 0.15 12.1 0.1 4.8 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.6 CEP10458.1 - 0.00012 22.0 0.1 2.4 8.2 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CEP10458.1 - 0.0033 17.3 0.0 3.7 7.5 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CEP10458.1 - 0.0048 16.5 0.0 11 5.7 0.0 4.0 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP10458.1 - 0.051 13.6 2.0 4.4 7.4 0.0 4.5 4 1 1 5 5 5 0 RNA binding motif Sua5_yciO_yrdC PF01300.18 CEP10459.1 - 2.7e-54 183.4 0.0 3.7e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CEP10459.1 - 7.4e-32 110.7 0.1 1.4e-31 109.8 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding COPIIcoated_ERV PF07970.12 CEP10460.1 - 2e-74 250.2 1.6 2.6e-74 249.8 1.6 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEP10460.1 - 1.2e-28 99.3 1.3 2.4e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Enolase_C PF00113.22 CEP10461.1 - 4.5e-153 508.7 0.1 5.9e-153 508.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CEP10461.1 - 4.3e-56 188.7 0.0 7.2e-56 188.0 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CEP10461.1 - 5.9e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CEP10461.1 - 0.002 17.4 0.1 0.0041 16.3 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus AA_kinase PF00696.28 CEP10463.1 - 1.2e-38 133.1 0.4 1.8e-38 132.5 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CEP10463.1 - 3.1e-07 30.3 0.3 1.1e-06 28.5 0.1 2.0 2 0 0 2 2 2 1 PUA domain UL16 PF17622.2 CEP10463.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Viral unique long protein 16 Nucleotid_trans PF03407.16 CEP10463.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF3246 PF11596.8 CEP10464.1 - 0.76 9.2 15.6 0.69 9.3 11.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Mg_trans_NIPA PF05653.14 CEP10465.1 - 2.2e-93 312.6 27.3 2.9e-93 312.2 27.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEP10465.1 - 1.4e-06 28.6 7.6 1.4e-06 28.6 7.6 3.5 3 1 0 3 3 3 2 EamA-like transporter family Cofilin_ADF PF00241.20 CEP10466.1 - 3.9e-13 49.3 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 CEP10466.1 - 7e-08 32.9 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEP10466.1 - 0.012 16.0 0.2 0.069 13.6 0.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4464 PF14713.6 CEP10466.1 - 0.32 10.5 7.9 0.67 9.5 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) DUF334 PF03904.13 CEP10466.1 - 2 7.9 11.5 3 7.3 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) TetR_C_23 PF17931.1 CEP10466.1 - 6.3 6.9 8.4 76 3.4 6.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4638 PF15472.6 CEP10466.1 - 7.1 6.3 14.9 0.18 11.5 6.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4638) eIF3_subunit PF08597.10 CEP10466.1 - 9.4 6.1 24.0 20 5.0 24.0 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CAP_GLY PF01302.25 CEP10467.1 - 1.5e-18 66.6 0.1 2.9e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CEP10467.1 - 2.1e-05 24.2 1.3 3.6e-05 23.5 1.3 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle PNRC PF15365.6 CEP10468.1 - 9.7e-09 34.8 6.2 2.1e-08 33.7 6.2 1.6 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif Dehydrin PF00257.19 CEP10468.1 - 0.071 13.7 6.7 0.11 13.1 6.7 1.2 1 0 0 1 1 1 0 Dehydrin DDE_Tnp_1_7 PF13843.6 CEP10468.1 - 0.28 10.4 6.4 0.4 9.9 6.4 1.2 1 0 0 1 1 1 0 Transposase IS4 WDCP PF15390.6 CEP10468.1 - 0.65 8.3 7.0 0.64 8.3 7.0 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family SR-25 PF10500.9 CEP10468.1 - 0.81 9.3 21.5 1.1 8.8 21.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 CEP10468.1 - 1.1 8.0 8.9 1.1 7.9 8.9 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CEP10468.1 - 2.1 7.5 4.3 2.2 7.4 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LMBR1 PF04791.16 CEP10468.1 - 4 6.2 5.7 4.9 5.9 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec62 PF03839.16 CEP10468.1 - 6.2 6.3 9.6 8.4 5.8 9.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 CEP10468.1 - 8.6 5.1 7.9 11 4.7 7.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter P_C PF06640.11 CEP10468.1 - 8.7 6.4 8.6 11 6.1 8.6 1.2 1 0 0 1 1 1 0 P protein C-terminus Ribosomal_S3_C PF00189.20 CEP10469.1 - 1.7e-22 79.7 1.1 6e-22 78.0 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CEP10469.1 - 1.4e-12 47.3 0.1 2.4e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CEP10469.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ASL_C PF08328.11 CEP10470.1 - 0.0085 16.2 1.0 0.015 15.3 1.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal RNA_pol_Rpb2_45 PF10385.9 CEP10470.1 - 0.057 13.7 5.0 2.9 8.2 0.1 3.4 1 1 2 3 3 3 0 RNA polymerase beta subunit external 1 domain PTPRCAP PF15713.5 CEP10470.1 - 0.06 13.6 3.0 0.1 12.9 3.0 1.4 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Phage_antitermQ PF06530.12 CEP10470.1 - 0.071 13.0 0.8 0.12 12.3 0.8 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q TSC22 PF01166.18 CEP10470.1 - 0.084 13.2 1.0 0.084 13.2 1.0 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family REV1_C PF16727.5 CEP10470.1 - 0.17 12.3 0.2 0.17 12.3 0.2 1.7 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Meis_PKNOX_N PF16493.5 CEP10470.1 - 0.3 11.4 2.6 0.37 11.2 0.5 2.0 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 V_ATPase_I PF01496.19 CEP10470.1 - 0.62 7.9 8.5 0.77 7.6 8.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SMC_Nse1 PF07574.13 CEP10470.1 - 1 9.2 9.6 0.41 10.5 6.8 1.6 1 1 1 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex DivIC PF04977.15 CEP10470.1 - 2.2 8.1 12.1 3.4 7.5 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator Abhydrolase_1 PF00561.20 CEP10472.1 - 6.5e-16 58.7 0.2 7e-15 55.4 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP10472.1 - 1e-15 57.7 0.0 2.7e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP10472.1 - 1.7e-10 41.9 0.0 2.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CEP10472.1 - 0.0019 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 CEP10472.1 - 0.013 15.1 0.2 2.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF1100 PF06500.11 CEP10472.1 - 0.027 13.3 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Lipase_3 PF01764.25 CEP10472.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 CEP10472.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 CEP10472.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) DEAD_2 PF06733.15 CEP10472.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 Acetyltransf_1 PF00583.25 CEP10473.1 - 8.2e-07 29.3 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CEP10473.1 - 0.0028 17.6 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF2863 PF11062.8 CEP10473.1 - 0.033 12.6 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) TPR_2 PF07719.17 CEP10474.1 - 2.6e-12 45.8 0.1 0.00021 21.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10474.1 - 5e-12 45.1 0.0 0.00029 20.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10474.1 - 4.5e-07 29.4 0.0 0.01 15.5 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CEP10474.1 - 6.9e-06 25.9 0.1 0.0036 17.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP10474.1 - 0.00026 21.6 0.0 0.019 15.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP10474.1 - 0.0016 18.3 0.4 0.68 10.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP10474.1 - 0.0018 18.9 0.1 0.36 11.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 CEP10474.1 - 0.002 18.2 0.1 0.033 14.2 0.1 2.1 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 CEP10474.1 - 0.007 16.6 0.2 2 8.7 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP10474.1 - 0.0088 16.5 0.1 0.058 13.9 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP10474.1 - 0.017 15.3 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SPO22 PF08631.10 CEP10474.1 - 0.044 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Nsp1_C PF05064.13 CEP10475.1 - 2.9e-34 117.3 11.3 2.9e-34 117.3 11.3 1.9 1 1 1 2 2 2 1 Nsp1-like C-terminal region Latrotoxin_C PF15658.6 CEP10475.1 - 0.12 12.1 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Med9 PF07544.13 CEP10476.1 - 9.2e-09 35.3 0.4 1.2e-08 34.9 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_CI_repr PF07022.13 CEP10477.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DUF2076 PF09849.9 CEP10479.1 - 0.046 13.8 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1176 PF06674.11 CEP10480.1 - 0.12 11.8 4.7 0.095 12.1 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1176) Sipho_Gp157 PF05565.11 CEP10480.1 - 0.12 12.4 0.1 4.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Ig_GlcNase PF18368.1 CEP10480.1 - 0.31 11.2 4.5 6.4 7.0 0.3 3.2 2 1 1 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain DDE_3 PF13358.6 CEP10482.1 - 1.3e-22 80.2 0.0 1.2e-15 57.6 0.0 2.0 2 0 0 2 2 2 2 DDE superfamily endonuclease Dam PF05869.11 CEP10483.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) Phage_lambda_P PF06992.11 CEP10483.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Replication protein P CENP-F_leu_zip PF10473.9 CEP10486.1 - 0.00049 20.1 6.2 0.00067 19.7 6.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CEP10486.1 - 0.0095 16.5 6.7 0.014 16.0 6.7 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region COMP PF11598.8 CEP10486.1 - 0.0098 16.3 1.1 0.62 10.6 0.0 2.5 2 0 0 2 2 2 1 Cartilage oligomeric matrix protein P66_CC PF16563.5 CEP10486.1 - 0.024 14.2 6.7 0.21 11.2 0.7 2.8 2 1 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 TMF_TATA_bd PF12325.8 CEP10486.1 - 0.089 13.0 4.7 0.32 11.2 4.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1351 PF07083.11 CEP10486.1 - 0.2 11.4 7.1 0.25 11.1 5.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) Spc7 PF08317.11 CEP10486.1 - 0.26 10.2 7.5 0.29 10.0 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CEP10486.1 - 0.26 11.5 5.6 0.055 13.6 2.3 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nefa_Nip30_N PF10187.9 CEP10486.1 - 0.4 11.1 6.6 0.31 11.4 2.2 2.2 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4200 PF13863.6 CEP10486.1 - 0.51 10.7 11.6 0.73 10.2 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CC2-LZ PF16516.5 CEP10486.1 - 0.62 10.5 9.4 2.8 8.4 2.3 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4078 PF13300.6 CEP10486.1 - 0.66 10.3 5.3 1.2 9.5 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) OmpH PF03938.14 CEP10486.1 - 1.7 9.0 9.3 2.1 8.7 9.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 CEP10486.1 - 2.5 7.9 9.5 6.3 6.6 1.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 CEP10486.1 - 5.7 7.2 10.5 5.1 7.4 5.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YqzL PF14006.6 CEP10487.1 - 0.068 13.5 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 YqzL-like protein Spore_coat_CotO PF14153.6 CEP10488.1 - 0.11 12.5 5.6 0.12 12.3 5.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DDE_3 PF13358.6 CEP10489.1 - 1e-05 25.4 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP10489.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain rve PF00665.26 CEP10491.1 - 3.2e-20 72.5 0.0 9.7e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP10491.1 - 1.5e-18 66.6 0.2 3.3e-18 65.5 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP10491.1 - 2e-05 24.7 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CEP10491.1 - 0.0018 18.0 0.0 0.006 16.3 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain ESX-1_EspG PF14011.6 CEP10492.1 - 0.074 12.6 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 EspG family gag-asp_proteas PF13975.6 CEP10493.1 - 7.5e-05 23.2 0.3 0.00019 22.0 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP10493.1 - 0.0005 20.7 0.2 0.001 19.7 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease DUF2492 PF10678.9 CEP10493.1 - 0.025 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) HrcA_DNA-bdg PF03444.15 CEP10494.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Orn_Arg_deC_N PF02784.16 CEP10496.1 - 1.3e-72 244.2 0.0 1.6e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CEP10496.1 - 1.3e-21 76.6 0.0 1.8e-21 76.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 CEP10496.1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel polyprenyl_synt PF00348.17 CEP10497.1 - 5.9e-68 228.7 0.0 1e-67 227.9 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase Kelch_6 PF13964.6 CEP10498.1 - 4.4e-22 77.6 8.0 1.7e-06 28.1 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CEP10498.1 - 1.9e-20 72.2 6.9 1.2e-06 28.0 0.0 6.4 6 2 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CEP10498.1 - 4.5e-19 67.6 0.7 3e-05 23.8 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CEP10498.1 - 2.7e-15 56.1 16.4 9.6e-06 25.5 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEP10498.1 - 2.2e-14 53.3 15.3 0.00028 21.1 0.1 6.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP10498.1 - 5.7e-13 48.5 3.5 0.05 13.6 0.0 6.7 6 0 0 6 6 6 3 Kelch motif YqhR PF11085.8 CEP10498.1 - 0.003 17.5 0.2 0.003 17.5 0.2 2.4 2 1 0 2 2 2 1 Conserved membrane protein YqhR Secretin PF00263.21 CEP10498.1 - 0.013 15.1 0.3 0.079 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial type II and III secretion system protein ASC PF00858.24 CEP10498.1 - 0.31 9.9 0.0 0.31 9.9 0.0 3.1 1 1 1 3 3 3 0 Amiloride-sensitive sodium channel DUF1011 PF06237.12 CEP10498.1 - 2.7 8.4 5.8 30 5.0 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1011) Syndecan PF01034.20 CEP10498.1 - 7 6.7 8.2 0.1 12.5 0.3 2.1 2 0 0 2 2 1 0 Syndecan domain RtcR PF06956.11 CEP10500.1 - 0.021 14.2 0.1 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase DUF4404 PF14357.6 CEP10500.1 - 0.12 13.0 0.1 1.4 9.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Img2 PF05046.14 CEP10501.1 - 3.4e-27 94.5 0.1 4.1e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CEP10501.1 - 0.013 16.0 0.1 0.019 15.5 0.1 1.4 1 1 0 1 1 1 0 Translation initiation factor SUI1 ORC3_N PF07034.11 CEP10502.1 - 4.4e-65 220.0 1.2 9.5e-65 218.9 0.2 2.0 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CEP10502.1 - 3e-36 124.6 2.5 5.2e-21 75.2 0.1 3.1 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Q_salvage PF10343.9 CEP10503.1 - 1.3e-118 395.7 0.1 1.5e-118 395.5 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Nbl1_Borealin_N PF10444.9 CEP10503.1 - 0.18 11.5 0.2 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal E1-E2_ATPase PF00122.20 CEP10504.1 - 2.1e-51 174.0 0.1 2.1e-51 174.0 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CEP10504.1 - 8e-15 55.7 3.6 2.6e-14 54.0 2.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP10504.1 - 2.6e-14 52.7 0.1 7.2e-14 51.2 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP10504.1 - 5.9e-05 22.9 0.5 0.00014 21.7 0.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP10504.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Metallophos PF00149.28 CEP10505.1 - 2.7e-11 44.3 0.0 7.1e-11 43.0 0.0 1.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Syntaxin_2 PF14523.6 CEP10506.1 - 3e-23 82.1 5.3 3e-23 82.1 5.3 2.8 2 1 0 3 3 3 1 Syntaxin-like protein Syntaxin PF00804.25 CEP10506.1 - 2.3e-06 27.4 17.3 4.7e-06 26.4 17.2 1.7 1 1 0 1 1 1 1 Syntaxin CEP209_CC5 PF16574.5 CEP10506.1 - 0.12 12.5 14.2 0.8 9.9 13.8 2.2 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 FUSC PF04632.12 CEP10506.1 - 0.16 10.4 0.5 0.19 10.2 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 CEP10506.1 - 0.64 8.8 16.4 0.96 8.3 15.5 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CEP10506.1 - 1.1 9.3 11.2 3.4 7.7 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CEP10506.1 - 1.8 9.0 7.2 0.45 11.0 0.4 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF501 PF04417.12 CEP10506.1 - 3.9 7.3 6.1 1.5 8.6 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) TMPIT PF07851.13 CEP10506.1 - 7.4 5.7 7.9 13 4.9 7.9 1.6 1 0 0 1 1 1 0 TMPIT-like protein TAF8_C PF10406.9 CEP10506.1 - 9.4 6.9 7.2 2.8 8.6 0.3 3.1 3 1 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term Fumble PF03630.14 CEP10507.1 - 1.9e-135 451.3 0.6 3e-135 450.7 0.6 1.3 1 1 0 1 1 1 1 Fumble Peptidase_S10 PF00450.22 CEP10508.1 - 4.7e-61 207.4 0.2 8e-61 206.7 0.2 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Adaptin_N PF01602.20 CEP10509.1 - 5.8e-148 493.7 6.1 6.9e-148 493.5 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CEP10509.1 - 1e-22 80.5 1.1 1e-22 80.5 1.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 CEP10509.1 - 4.5e-09 36.6 0.4 4.5e-09 36.6 0.4 3.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 CEP10509.1 - 0.0062 16.3 0.0 0.029 14.1 0.0 2.2 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 CEP10509.1 - 0.025 15.0 4.5 0.91 10.0 0.1 4.4 6 0 0 6 6 6 0 HEAT repeats HEAT PF02985.22 CEP10509.1 - 0.17 12.2 0.3 1.4e+02 3.2 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat 4HBT PF03061.22 CEP10510.1 - 4.2e-13 49.5 0.0 1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Whi5 PF08528.11 CEP10510.1 - 0.0044 16.6 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Whi5 like Ndc1_Nup PF09531.10 CEP10510.1 - 0.021 13.5 1.8 0.054 12.2 1.8 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC35F PF06027.12 CEP10511.1 - 1.2e-97 327.1 23.2 1.4e-97 326.8 23.2 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CEP10511.1 - 1.5e-10 41.4 30.4 2e-05 24.8 10.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CEP10511.1 - 2.7e-09 36.4 6.0 2.7e-09 36.4 6.0 1.8 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Sec62 PF03839.16 CEP10511.1 - 2.6 7.5 8.3 5.7 6.4 8.3 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 TBP PF00352.21 CEP10512.1 - 3.6e-68 225.5 0.1 1.9e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CEP10512.1 - 3.1e-05 24.0 0.0 0.22 11.6 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CEP10512.1 - 0.058 13.2 0.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) PX PF00787.24 CEP10513.1 - 6.2e-15 55.2 0.2 1e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.19 CEP10513.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 SNARE domain PP2C PF00481.21 CEP10514.1 - 5.6e-69 232.6 0.1 6.4e-69 232.4 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEP10514.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C LptF_LptG PF03739.14 CEP10515.1 - 2.6 6.8 5.1 9.6 4.9 5.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG NuA4 PF09340.10 CEP10516.1 - 2.3e-23 81.8 0.1 2.3e-23 81.8 0.1 2.3 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Nucleo_P87 PF07267.11 CEP10516.1 - 4.9 5.9 14.0 5.9 5.6 14.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAD_binding_4 PF07993.12 CEP10517.1 - 1.4e-48 165.3 0.0 2.3e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 CEP10517.1 - 1.6e-09 37.8 0.0 5.5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 CEP10517.1 - 1.4e-05 24.7 0.0 3.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.21 CEP10517.1 - 0.00019 21.0 0.2 0.00066 19.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP10517.1 - 0.14 11.1 0.7 7 5.6 0.0 2.6 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family CsbD PF05532.12 CEP10518.1 - 0.022 14.6 0.8 0.066 13.1 0.8 1.8 1 0 0 1 1 1 0 CsbD-like Mito_carr PF00153.27 CEP10519.1 - 2.7e-22 78.5 0.1 1.1e-09 38.0 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein Dr_adhesin PF12393.8 CEP10520.1 - 0.54 10.6 3.7 1.7 9.0 3.7 1.9 1 0 0 1 1 1 0 Dr family adhesin CP2 PF04516.15 CEP10522.1 - 4.3e-54 183.2 0.2 1.1e-53 181.9 0.2 1.7 1 0 0 1 1 1 1 CP2 transcription factor Lactamase_B PF00753.27 CEP10522.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF755 PF05501.11 CEP10522.1 - 2.7 8.3 38.5 0.33 11.2 9.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2009 PF09418.10 CEP10523.1 - 2.6e-197 656.4 0.3 4e-197 655.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CEP10523.1 - 4.1e-05 23.6 7.5 4.1e-05 23.6 7.5 2.3 2 0 0 2 2 2 1 B-box zinc finger DHC_N1 PF08385.12 CEP10523.1 - 0.021 13.5 0.1 0.035 12.7 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 IBR PF01485.21 CEP10523.1 - 0.036 14.3 4.7 0.14 12.4 4.7 2.0 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain GlcNAc PF11397.8 CEP10523.1 - 0.071 12.6 1.1 0.08 12.4 0.1 1.5 2 0 0 2 2 2 0 Glycosyltransferase (GlcNAc) CEBP_ZZ PF16366.5 CEP10523.1 - 0.079 13.2 6.6 0.2 11.9 6.6 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-met PF12874.7 CEP10524.1 - 3e-09 36.9 53.9 0.013 15.9 0.5 8.4 9 0 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP10524.1 - 8.1e-06 26.3 72.2 0.31 12.0 2.0 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP10524.1 - 0.00016 21.9 66.2 0.074 13.4 1.1 8.3 8 0 0 8 8 8 6 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 CEP10524.1 - 0.028 13.0 0.1 0.028 13.0 0.1 6.6 7 1 1 8 8 8 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 CEP10524.1 - 0.07 13.5 40.2 0.55 10.6 2.3 7.5 2 2 4 7 7 7 0 C2H2 type zinc-finger (2 copies) PIF1 PF05970.14 CEP10525.1 - 1.4e-21 77.1 0.1 1e-14 54.5 0.0 2.0 2 0 0 2 2 2 2 PIF1-like helicase p450 PF00067.22 CEP10526.1 - 8e-73 245.7 0.1 1.1e-72 245.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoaE PF01121.20 CEP10526.1 - 0.092 12.4 0.6 4.9 6.8 0.2 3.2 3 1 0 3 3 3 0 Dephospho-CoA kinase WD40 PF00400.32 CEP10527.1 - 1.1e-57 190.6 12.0 4.8e-08 33.5 1.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP10527.1 - 4.2e-20 71.8 0.0 0.003 17.8 0.0 6.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 CEP10527.1 - 5.2e-12 45.9 5.1 1.5e-08 34.8 0.7 2.3 2 0 0 2 2 2 2 Tup N-terminal Ge1_WD40 PF16529.5 CEP10527.1 - 6.4e-07 28.6 0.3 0.6 9.0 0.0 4.4 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEP10527.1 - 7.9e-07 28.7 0.0 0.0076 15.6 0.0 3.7 2 2 1 4 4 4 2 WD40-like domain PD40 PF07676.12 CEP10527.1 - 0.0015 18.4 1.2 0.91 9.5 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CEP10527.1 - 0.0025 16.4 0.6 1.1 7.7 0.1 2.8 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 CEP10527.1 - 0.0039 16.6 0.1 2.7 7.3 0.0 3.1 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ret2_MD PF18528.1 CEP10527.1 - 0.036 14.4 0.0 84 3.6 0.0 3.7 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF5122 PF17164.4 CEP10527.1 - 0.078 13.3 1.8 52 4.2 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Nup160 PF11715.8 CEP10527.1 - 0.1 11.2 2.0 11 4.6 0.1 3.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Chorismate_bind PF00425.18 CEP10528.1 - 7e-85 284.7 0.0 4.1e-84 282.2 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 CEP10528.1 - 1.9e-32 112.6 0.0 1.6e-22 80.2 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CEP10528.1 - 3.7e-14 53.1 0.4 5.8e-12 46.0 0.4 3.1 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CEP10528.1 - 0.00023 21.0 0.3 0.0026 17.5 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 Vfa1 PF08432.10 CEP10530.1 - 6e-34 118.0 5.5 8e-34 117.5 5.5 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Menin PF05053.13 CEP10530.1 - 0.0094 14.4 7.6 0.011 14.1 7.6 1.1 1 0 0 1 1 1 1 Menin SR-25 PF10500.9 CEP10530.1 - 0.015 14.9 10.9 0.022 14.4 10.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tim54 PF11711.8 CEP10530.1 - 0.017 13.9 4.9 0.024 13.4 4.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF908 PF06012.12 CEP10530.1 - 0.26 10.7 8.5 0.33 10.3 8.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Neur_chan_memb PF02932.16 CEP10530.1 - 0.53 10.3 2.1 0.57 10.2 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CEP10530.1 - 0.89 8.7 4.3 1.1 8.5 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pacs-1 PF10254.9 CEP10530.1 - 1.1 8.2 6.3 1.4 7.8 6.3 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein NOA36 PF06524.12 CEP10530.1 - 1.1 8.5 12.0 2.1 7.6 12.0 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CEP10530.1 - 1.2 8.8 4.6 2.4 7.8 4.6 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 CEP10530.1 - 1.4 7.1 9.6 1.6 6.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 CEP10530.1 - 1.6 6.8 11.1 2 6.4 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR3 PF03666.13 CEP10530.1 - 1.9 7.2 9.9 2.3 6.9 9.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CEP10530.1 - 3.9 6.3 6.9 5.2 5.9 6.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CEP10530.1 - 4 6.1 8.5 5.2 5.7 8.5 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_L34e PF01199.18 CEP10531.1 - 1.4e-45 153.5 6.0 1.8e-45 153.2 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF4191 PF13829.6 CEP10532.1 - 2.2 7.5 9.6 2.2 7.6 3.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) RIC1 PF07064.13 CEP10533.1 - 7.7e-85 284.3 0.0 1.7e-84 283.2 0.0 1.7 1 1 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CEP10533.1 - 3.9e-05 23.9 0.1 0.0068 16.7 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP10533.1 - 0.046 13.0 0.4 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain CorA PF01544.18 CEP10534.1 - 1.1e-44 152.9 0.2 1.8e-44 152.2 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Shikimate_DH PF01488.20 CEP10534.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAM176 PF14851.6 CEP10535.1 - 0.051 13.2 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 FAM176 family zf-C2H2_12 PF18658.1 CEP10536.1 - 0.15 11.6 5.6 1.3 8.6 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type COX5B PF01215.19 CEP10537.1 - 1.5e-44 150.8 0.0 1.8e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 CEP10537.1 - 0.0017 18.4 0.2 0.0032 17.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain zf-C4_Topoisom PF01396.19 CEP10537.1 - 0.0058 16.4 0.5 0.91 9.4 0.0 2.3 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Rad50_zn_hook PF04423.14 CEP10537.1 - 0.14 12.0 0.1 0.83 9.5 0.0 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif COG6 PF06419.11 CEP10537.1 - 0.17 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 HSP9_HSP12 PF04119.12 CEP10538.1 - 0.0026 18.1 0.2 0.024 15.0 0.0 2.8 2 0 0 2 2 2 1 Heat shock protein 9/12 HTH_6 PF01418.17 CEP10538.1 - 0.95 9.5 6.2 2.7 8.0 0.9 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF3618 PF12277.8 CEP10538.1 - 2.5 8.4 5.2 7.9 6.8 1.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3618) GIT_CC PF16559.5 CEP10538.1 - 2.7 7.9 12.6 21 5.1 0.5 4.8 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Duo1 PF08651.10 CEP10538.1 - 5.5 6.8 13.9 1 9.2 0.3 5.3 4 1 1 5 5 5 0 DASH complex subunit Duo1 Cep57_CLD_2 PF14197.6 CEP10538.1 - 9.9 6.3 12.9 0.58 10.3 3.0 3.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 NPL4 PF05021.15 CEP10539.1 - 1.1e-112 376.4 0.0 1.4e-112 376.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CEP10539.1 - 2.4e-68 228.8 0.1 5e-68 227.8 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CEP10539.1 - 3.7e-11 43.3 0.0 8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.24 CEP10539.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 PB1 domain Sec7 PF01369.20 CEP10540.1 - 4.3e-32 111.3 0.6 1.3e-31 109.7 0.6 1.9 1 1 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CEP10540.1 - 1.4e-31 109.3 0.3 7.2e-31 107.0 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Lebercilin PF15619.6 CEP10540.1 - 0.056 13.1 5.3 0.12 12.0 5.3 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Big_3_5 PF16640.5 CEP10540.1 - 5 7.4 8.4 0.53 10.5 3.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) adh_short PF00106.25 CEP10541.1 - 4e-27 94.9 0.0 8.1e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEP10541.1 - 4.4e-14 52.6 0.0 9.6e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP10541.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP10541.1 - 0.00047 19.7 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 CEP10542.1 - 7.3e-17 61.7 0.0 2e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP10542.1 - 4.5e-16 59.3 0.0 1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP10542.1 - 2.7e-14 53.2 0.0 1.4e-13 50.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP10542.1 - 3.9e-13 49.9 0.0 7.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP10542.1 - 2e-09 38.1 0.0 6.4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP10542.1 - 9.8e-07 28.4 0.0 1.9e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 CEP10542.1 - 0.0003 20.2 0.0 0.0008 18.8 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 CEP10542.1 - 0.0043 15.7 0.0 0.0073 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 CEP10542.1 - 0.0069 15.9 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 CEP10542.1 - 0.0089 15.5 0.0 2.4 7.5 0.0 3.4 3 1 1 4 4 4 1 Tellurite resistance protein TehB MetW PF07021.12 CEP10542.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 CEP10542.1 - 0.081 12.8 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_2 PF00891.18 CEP10542.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Glycos_transf_1 PF00534.20 CEP10543.1 - 1.4e-21 76.7 0.0 3.6e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP10543.1 - 1.7e-13 51.2 0.0 7.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEP10543.1 - 6.8e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3450 PF11932.8 CEP10544.1 - 0.069 12.5 0.2 0.069 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) G6PD_C PF02781.16 CEP10545.1 - 1.8e-111 372.0 0.1 4.9e-111 370.6 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEP10545.1 - 5.3e-56 190.0 0.2 3.9e-47 161.2 0.0 3.0 3 0 0 3 3 3 2 Glucose-6-phosphate dehydrogenase, NAD binding domain TLD PF07534.16 CEP10546.1 - 1.9e-41 141.6 0.0 2.2e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 TLD CoA_transf_3 PF02515.17 CEP10547.1 - 1.5e-96 323.7 0.0 2.4e-96 323.1 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III CDC24_OB3 PF17244.2 CEP10548.1 - 9.7e-54 182.4 0.0 2e-53 181.4 0.0 1.4 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 CEP10548.1 - 4.7e-25 88.6 0.7 1.1e-24 87.4 0.7 1.7 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 CEP10548.1 - 2.4e-19 69.7 0.1 4.1e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 tRNA_anti-codon PF01336.25 CEP10548.1 - 0.037 14.0 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain GPI-anchored PF10342.9 CEP10549.1 - 6.1e-05 23.7 0.6 6.1e-05 23.7 0.6 1.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 CEP10550.1 - 1.1e-68 231.5 0.0 1.7e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10550.1 - 6.2e-41 140.4 0.0 1.1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP10550.1 - 1.5e-08 34.3 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP10550.1 - 0.0018 17.7 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP10550.1 - 0.03 14.3 0.8 0.45 10.4 0.5 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Act-Frag_cataly PF09192.10 CEP10550.1 - 0.06 12.7 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Reductase_C PF14759.6 CEP10550.1 - 0.09 13.3 0.1 1.9 9.1 0.0 2.5 2 0 0 2 2 2 0 Reductase C-terminal CotH PF08757.11 CEP10551.1 - 1.1e-40 140.1 1.8 1.7e-40 139.5 1.8 1.2 1 0 0 1 1 1 1 CotH kinase protein NAP PF00956.18 CEP10551.1 - 0.019 14.1 0.3 0.031 13.4 0.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) NAD_kinase PF01513.21 CEP10554.1 - 4e-73 246.2 0.0 9.6e-72 241.6 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase Stn1 PF10451.9 CEP10554.1 - 0.094 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DAGK_cat PF00781.24 CEP10554.1 - 0.15 11.6 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain PDZ_5 PF17817.1 CEP10555.1 - 0.053 13.8 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 PDZ domain zf-RVT PF13966.6 CEP10556.1 - 1.3e-10 41.8 0.4 2.3e-10 41.1 0.4 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Glyco_hydro_17 PF00332.18 CEP10557.1 - 2.2e-11 44.0 6.3 3.4e-07 30.2 0.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 RGS PF00615.19 CEP10558.1 - 1.3e-12 48.0 5.4 3.1e-12 46.8 5.4 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4528 PF15031.6 CEP10558.1 - 0.13 12.3 2.4 0.25 11.4 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) NAS PF03059.16 CEP10559.1 - 2.3e-05 23.9 0.1 2.3e-05 23.9 0.1 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Pkinase PF00069.25 CEP10560.1 - 3.2e-58 197.2 0.0 5.3e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10560.1 - 2.4e-26 92.6 0.0 3.4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP10560.1 - 5.8e-05 22.5 0.0 9.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP10560.1 - 0.00062 19.7 1.4 0.0011 18.9 1.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEP10560.1 - 0.0017 17.7 1.4 0.0033 16.8 1.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP10560.1 - 0.0032 16.3 1.7 0.005 15.7 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase NAS PF03059.16 CEP10560.1 - 0.0082 15.5 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Nicotianamine synthase protein UPF0767 PF15990.5 CEP10560.1 - 0.49 10.6 2.5 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 UPF0767 family ATP-synt_10 PF05176.14 CEP10561.1 - 3.2e-53 180.6 0.2 3.9e-53 180.3 0.2 1.0 1 0 0 1 1 1 1 ATP10 protein DUF4512 PF14975.6 CEP10561.1 - 0.051 14.4 0.1 0.13 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) TMF_TATA_bd PF12325.8 CEP10562.1 - 5.6e-32 110.4 17.0 5.6e-32 110.4 17.0 7.9 2 1 6 8 8 8 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CEP10562.1 - 7.3e-16 57.9 17.7 7.3e-16 57.9 17.7 11.2 3 2 6 10 10 10 2 TATA element modulatory factor 1 DNA binding ADK PF00406.22 CEP10563.1 - 4.6e-47 159.9 0.0 6.7e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEP10563.1 - 5e-37 127.4 0.0 5e-37 127.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP10563.1 - 2.7e-11 44.1 0.0 4.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP10563.1 - 1.1e-07 32.1 0.0 3e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CEP10563.1 - 3.3e-05 23.6 0.8 0.13 11.9 0.1 2.5 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 CEP10563.1 - 5.6e-05 22.5 0.0 8.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 CEP10563.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CEP10563.1 - 0.3 11.3 1.1 0.42 10.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain EF-1_beta_acid PF10587.9 CEP10563.1 - 1.7 9.2 6.3 4.5 7.8 6.3 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Prok-RING_1 PF14446.6 CEP10564.1 - 0.028 14.4 1.3 0.028 14.4 1.3 4.2 4 2 1 5 5 5 0 Prokaryotic RING finger family 1 zf-C4_Topoisom PF01396.19 CEP10564.1 - 0.085 12.7 6.0 1.7 8.5 0.4 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf_UBZ PF18439.1 CEP10564.1 - 0.13 11.8 5.2 2.8 7.6 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4611 PF15387.6 CEP10564.1 - 0.19 12.0 1.2 23 5.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zinc_ribbon_4 PF13717.6 CEP10564.1 - 0.3 11.1 5.0 5.5 7.0 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCHC PF00098.23 CEP10564.1 - 0.31 11.2 0.3 0.31 11.2 0.3 4.8 6 0 0 6 6 6 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP10564.1 - 0.33 10.7 7.5 0.83 9.4 0.0 3.5 3 0 0 3 3 3 0 C2H2 zinc-finger zf-ribbon_3 PF13248.6 CEP10564.1 - 0.35 10.3 8.2 1.2 8.6 0.3 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_7 PF02591.15 CEP10564.1 - 0.36 11.1 5.7 0.63 10.3 0.5 3.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain PHD PF00628.29 CEP10564.1 - 0.44 10.5 11.5 7.1 6.6 0.0 4.3 4 1 0 4 4 4 0 PHD-finger zinc_ribbon_2 PF13240.6 CEP10564.1 - 0.45 10.3 8.8 1.9 8.3 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEP10564.1 - 1.9 8.5 14.4 2.1 8.4 3.0 3.4 2 2 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CEP10564.1 - 2 8.5 14.7 8.7 6.5 4.7 3.4 2 2 0 2 2 2 0 Double zinc ribbon Ribosom_S12_S23 PF00164.25 CEP10565.1 - 5.7e-51 170.9 0.8 7.1e-51 170.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DnaJ_C PF01556.18 CEP10566.1 - 9.6e-40 136.1 0.5 1.3e-39 135.7 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP10566.1 - 4.3e-27 94.0 1.7 6.9e-27 93.4 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CEP10566.1 - 0.004 17.0 0.2 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 A repeated domain in UCH-protein Gemini_AL1_M PF08283.11 CEP10567.1 - 0.045 13.8 0.9 0.24 11.5 0.6 2.0 2 0 0 2 2 2 0 Geminivirus rep protein central domain F-box-like PF12937.7 CEP10568.1 - 1.9e-08 34.0 0.4 1.9e-08 34.0 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP10568.1 - 5.5e-07 29.3 3.3 9.4e-07 28.6 0.2 2.8 3 0 0 3 3 3 1 F-box domain IL4 PF00727.18 CEP10568.1 - 0.28 11.4 2.2 6.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Interleukin 4 WD40 PF00400.32 CEP10569.1 - 1.2e-07 32.3 13.7 0.37 11.8 0.1 6.9 6 2 1 7 7 7 3 WD domain, G-beta repeat Lactonase PF10282.9 CEP10569.1 - 7.1e-06 25.5 0.0 0.00062 19.1 0.0 2.5 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 CEP10569.1 - 0.0011 19.2 0.0 27 5.1 0.0 3.8 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 CEP10569.1 - 0.033 14.5 0.3 9.6 6.7 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Ge1_WD40 PF16529.5 CEP10569.1 - 0.047 12.6 0.0 5.6 5.8 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pribosyl_synth PF14572.6 CEP10570.1 - 6.2e-40 137.2 1.2 7.2e-33 114.2 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CEP10570.1 - 2.4e-33 114.5 0.0 6.6e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase SCP2 PF02036.17 CEP10570.1 - 1.9e-16 60.4 0.2 3.5e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Pribosyltran PF00156.27 CEP10570.1 - 1.7e-13 50.4 0.0 2.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEP10570.1 - 0.0087 15.5 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YliH PF10799.8 CEP10570.1 - 0.038 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) COQ7 PF03232.13 CEP10571.1 - 2.1e-76 255.5 0.0 2.4e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4499 PF14934.6 CEP10572.1 - 5.1e-15 55.6 0.5 9e-15 54.8 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 CEP10572.1 - 6.4e-12 45.9 0.0 9.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Peptidase_M49 PF03571.15 CEP10573.1 - 2.9e-226 752.2 0.8 3.7e-226 751.8 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M49 Peptidase_M24 PF00557.24 CEP10574.1 - 2.7e-50 171.0 0.0 5.2e-50 170.1 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEP10574.1 - 3.4e-22 78.5 0.0 3.5e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 CEP10574.1 - 0.13 13.0 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain PLDc_2 PF13091.6 CEP10575.1 - 1.1e-27 96.5 0.2 3.5e-27 94.9 0.2 1.9 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 CEP10575.1 - 0.0029 17.7 0.1 0.0083 16.3 0.1 1.8 1 0 0 1 1 1 1 Phospholipase D Active site motif FAM83 PF07894.12 CEP10575.1 - 0.0051 16.4 0.1 0.0051 16.4 0.1 3.6 2 1 1 3 3 3 1 FAM83 A-H DUF2528 PF10800.8 CEP10575.1 - 0.0079 16.8 0.4 0.027 15.1 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2528) MecA_N PF05223.11 CEP10575.1 - 0.034 14.4 2.3 0.099 12.9 2.3 1.7 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain DUF5122 PF17164.4 CEP10575.1 - 0.39 11.0 0.1 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller CENP-B_dimeris PF09026.10 CEP10575.1 - 3 8.3 15.1 1.6 9.2 5.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 CEP10576.1 - 2.7e-10 40.1 0.0 5e-09 35.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10576.1 - 0.0028 17.0 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5538 PF17692.1 CEP10576.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Myb_DNA-binding PF00249.31 CEP10577.1 - 2.3e-13 50.1 0.6 8.1e-13 48.3 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP10577.1 - 3.4e-12 46.4 1.6 6.4e-12 45.5 0.6 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 CEP10577.1 - 0.0056 16.9 0.0 0.0056 16.9 0.0 3.2 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 CEP10577.1 - 0.0092 16.0 0.0 0.0092 16.0 0.0 2.4 2 0 0 2 2 2 1 SLIDE Rap1_C PF11626.8 CEP10577.1 - 0.027 14.6 0.9 0.092 12.8 0.1 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 CEP10577.1 - 0.52 10.3 5.1 0.71 9.8 0.2 2.8 2 0 0 2 2 2 0 Myb DNA-binding like Carn_acyltransf PF00755.20 CEP10578.1 - 1.2e-210 701.2 0.0 1.3e-210 701.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FAD_binding_2 PF00890.24 CEP10579.1 - 2.7e-123 412.2 5.2 3.4e-123 411.8 5.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CEP10579.1 - 3.7e-45 153.0 0.9 5.7e-45 152.4 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CEP10579.1 - 3.5e-06 26.5 0.3 0.00078 18.8 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP10579.1 - 1.8e-05 24.1 0.5 0.018 14.3 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CEP10579.1 - 2.6e-05 23.5 2.0 0.014 14.5 2.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CEP10579.1 - 0.0026 17.1 0.3 0.0045 16.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CEP10579.1 - 0.0047 16.0 0.7 0.037 13.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CEP10579.1 - 0.04 13.5 1.0 0.067 12.8 1.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP10579.1 - 0.068 11.9 2.7 0.47 9.1 0.9 2.8 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.6 CEP10579.1 - 1.6 7.9 3.2 2.4 7.3 1.3 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase XhlA PF10779.9 CEP10581.1 - 0.73 10.1 4.5 11 6.3 0.2 3.2 2 1 1 3 3 3 0 Haemolysin XhlA DivIC PF04977.15 CEP10581.1 - 6.3 6.7 5.5 11 5.8 0.2 3.4 4 0 0 4 4 4 0 Septum formation initiator AMP-binding PF00501.28 CEP10582.1 - 5.5e-76 255.8 0.5 8.5e-39 133.3 0.1 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEP10582.1 - 6.4e-21 75.1 0.1 1.6e-20 73.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAM176 PF14851.6 CEP10583.1 - 0.0094 15.6 0.3 0.016 14.9 0.3 1.3 1 0 0 1 1 1 1 FAM176 family Sporozoite_P67 PF05642.11 CEP10583.1 - 0.03 12.4 0.0 0.036 12.2 0.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.16 CEP10583.1 - 0.05 12.8 0.7 0.068 12.4 0.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GRP PF07172.11 CEP10583.1 - 0.073 13.8 0.0 0.12 13.0 0.0 1.5 1 1 0 1 1 1 0 Glycine rich protein family Glyco_hydro_18 PF00704.28 CEP10584.1 - 4.6e-57 194.1 2.4 6.8e-38 131.1 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 CEP10584.1 - 8.5e-05 22.4 3.6 0.00033 20.5 3.6 2.1 1 0 0 1 1 1 1 Cellulose-binding domain CBM_5_12 PF02839.14 CEP10584.1 - 0.00025 21.5 4.3 0.00025 21.5 4.3 3.2 3 0 0 3 3 3 1 Carbohydrate binding domain Radical_SAM PF04055.21 CEP10585.1 - 6.8e-25 88.4 0.0 1.3e-24 87.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 CEP10585.1 - 2.2e-22 79.1 0.0 6.1e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 CEP10585.1 - 2.6e-22 79.6 0.0 5.5e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CEP10585.1 - 0.14 12.4 0.2 0.9 9.8 0.1 2.1 2 0 0 2 2 2 0 Flavodoxin domain TMEM164 PF14808.6 CEP10586.1 - 2.5e-13 49.9 0.0 3.2e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 CEP10586.1 - 0.012 15.2 1.0 0.015 14.9 1.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Lipoprotein_11 PF03260.13 CEP10586.1 - 0.017 14.5 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein GAPES2 PF17156.4 CEP10586.1 - 0.056 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain PINIT PF14324.6 CEP10588.1 - 7.7e-28 97.7 0.2 2.1e-27 96.3 0.2 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CEP10588.1 - 2.5e-20 71.9 0.7 4.7e-20 71.1 0.7 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CEP10588.1 - 2.7e-08 33.5 0.4 7.2e-08 32.1 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CEP10588.1 - 0.032 14.1 0.2 0.088 12.7 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2_9 PF16293.5 CEP10588.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) NusG_II PF07009.11 CEP10588.1 - 0.29 11.3 6.9 0.21 11.8 1.3 2.7 3 0 0 3 3 3 0 NusG domain II TMEM174 PF15029.6 CEP10588.1 - 0.31 10.7 1.6 0.43 10.3 0.4 1.9 1 1 0 1 1 1 0 Transmembrane protein 174 Mucin PF01456.17 CEP10588.1 - 0.37 10.8 9.1 0.69 9.9 9.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_3 PF08777.11 CEP10588.1 - 1.4 9.0 5.7 0.42 10.7 1.8 2.1 2 0 0 2 2 2 0 RNA binding motif End3 PF12761.7 CEP10589.1 - 4.1e-43 147.9 4.7 6.9e-43 147.1 4.7 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 CEP10589.1 - 1e-34 118.6 0.0 1.5e-30 105.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CEP10589.1 - 1.7e-07 31.5 0.4 0.0016 18.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEP10589.1 - 1.4e-06 27.5 0.2 3.1e-05 23.2 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEP10589.1 - 0.00013 21.6 2.5 0.074 13.0 0.5 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CEP10589.1 - 0.0087 15.9 0.1 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.11 CEP10589.1 - 0.024 15.0 48.7 0.21 12.0 48.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Laminin_II PF06009.12 CEP10589.1 - 0.061 13.3 10.3 0.12 12.4 1.7 2.2 1 1 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 CEP10589.1 - 0.79 9.9 6.3 1.2 9.3 5.6 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 CEP10589.1 - 1.3 9.7 10.2 6.1 7.5 0.7 2.7 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 CEP10589.1 - 1.4 7.7 15.4 0.53 9.1 3.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 CEP10589.1 - 2.1 8.8 8.7 0.1 13.0 1.4 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain YscO PF07321.12 CEP10589.1 - 2.7 7.9 20.5 51 3.8 20.2 2.2 1 1 0 1 1 1 0 Type III secretion protein YscO DUF2203 PF09969.9 CEP10589.1 - 3.5 8.4 6.2 5.2 7.8 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_L36e PF01158.18 CEP10590.1 - 8.8e-38 128.4 4.5 9.9e-38 128.3 4.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 CEP10590.1 - 0.063 12.8 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TetR_C_9 PF14514.6 CEP10590.1 - 0.078 13.1 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PK PF00224.21 CEP10591.1 - 3.4e-166 552.4 4.0 4.2e-166 552.1 4.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CEP10591.1 - 1.6e-36 125.1 0.0 4.6e-36 123.6 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEP10591.1 - 8.7e-06 25.0 0.2 2e-05 23.9 0.3 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CEP10591.1 - 0.13 11.3 1.0 0.27 10.2 0.1 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain ECH_2 PF16113.5 CEP10592.1 - 9.1e-10 38.5 0.0 5.5e-09 36.0 0.0 2.2 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase Spore_GerAC PF05504.11 CEP10592.1 - 2.6 8.2 5.3 0.45 10.7 1.0 1.9 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal YL1_C PF08265.11 CEP10592.1 - 8.6 6.2 7.5 19 5.1 0.2 4.0 4 0 0 4 4 4 0 YL1 nuclear protein C-terminal domain Pkinase PF00069.25 CEP10593.1 - 8.9e-76 254.7 0.0 1.2e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10593.1 - 9.8e-38 129.9 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CEP10593.1 - 4.4e-22 78.7 0.0 2.7e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 CEP10593.1 - 3.5e-08 33.1 0.0 4.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 CEP10593.1 - 3.9e-06 26.9 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 CEP10593.1 - 0.0018 17.9 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family KA1 PF02149.19 CEP10593.1 - 0.0034 17.1 0.0 0.095 12.5 0.0 2.6 2 0 0 2 2 2 1 Kinase associated domain 1 Haspin_kinase PF12330.8 CEP10593.1 - 0.0044 16.0 0.1 0.0075 15.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP10593.1 - 0.011 15.7 0.2 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.9 CEP10593.1 - 0.015 14.1 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 CEP10593.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc24 PF08286.11 CEP10594.1 - 0.00049 20.3 1.7 0.00049 20.3 1.7 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 DUF3417 PF11897.8 CEP10594.1 - 0.1 13.0 2.8 0.14 12.6 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) BLI1 PF17324.2 CEP10594.1 - 0.64 10.7 15.6 1.2 9.8 3.3 2.4 1 1 1 2 2 2 0 BLOC-1 interactor 1 WD40 PF00400.32 CEP10595.1 - 4e-39 131.9 21.3 5.9e-06 26.9 1.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 CEP10595.1 - 1.8e-22 79.6 0.2 4.2e-22 78.4 0.2 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 CEP10595.1 - 6.3e-09 36.0 1.8 0.024 14.9 0.3 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP10595.1 - 9e-06 24.6 7.2 0.038 12.6 0.1 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP10595.1 - 0.0015 18.0 0.0 1.2 8.3 0.0 3.0 2 1 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 CEP10595.1 - 0.076 13.5 0.6 17 6.1 0.1 4.2 5 1 0 5 5 5 0 PQQ-like domain Sel1 PF08238.12 CEP10596.1 - 1.2e-16 60.8 5.2 7.7e-08 32.8 0.4 4.3 4 1 1 5 5 5 3 Sel1 repeat TPR_3 PF07720.12 CEP10596.1 - 0.024 14.6 0.4 1.1 9.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Rtt106_N PF18215.1 CEP10596.1 - 0.12 12.2 1.0 0.31 10.8 0.3 2.1 3 0 0 3 3 3 0 Histone chaperone Rtt106 N-terminal domain Peptidase_M24 PF00557.24 CEP10598.1 - 5e-24 85.2 0.1 6.4e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 mit_SMPDase PF14724.6 CEP10599.1 - 0.0096 13.9 2.7 0.016 13.3 0.3 2.2 3 0 0 3 3 3 2 Mitochondrial-associated sphingomyelin phosphodiesterase WD40 PF00400.32 CEP10600.1 - 7e-39 131.1 22.9 1.8e-06 28.5 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 CEP10600.1 - 2.6e-09 36.3 10.2 0.48 9.0 0.0 6.2 3 2 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEP10600.1 - 6.3e-09 36.0 1.3 0.074 13.4 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP10600.1 - 2e-07 30.8 1.1 3.7e-07 29.9 1.1 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 CEP10600.1 - 2.5e-07 30.3 0.1 0.00062 19.2 0.0 2.2 1 1 0 1 1 1 1 WD40-like domain BBS2_Mid PF14783.6 CEP10600.1 - 4.3e-05 23.5 0.1 11 6.1 0.0 4.6 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 CEP10600.1 - 8.9e-05 22.2 0.0 0.0039 16.8 0.0 2.2 1 1 1 2 2 2 2 PQQ-like domain F-box PF00646.33 CEP10600.1 - 0.00012 21.8 0.2 0.00024 20.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain Bromodomain PF00439.25 CEP10601.1 - 2.1e-46 155.9 2.2 1.4e-22 79.5 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CEP10601.1 - 4.7e-17 61.9 0.0 2.3e-08 34.1 0.0 2.9 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation Cwf_Cwc_15 PF04889.12 CEP10601.1 - 0.051 13.3 29.3 0.052 13.3 11.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FlxA PF14282.6 CEP10601.1 - 0.087 12.8 0.3 0.087 12.8 0.3 3.3 3 0 0 3 3 3 0 FlxA-like protein Csm1_N PF18504.1 CEP10601.1 - 0.38 11.1 6.0 1.9 8.9 1.2 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain MCPVI PF02993.14 CEP10601.1 - 5.3 6.8 10.7 9.5 6.0 6.1 3.0 3 0 0 3 3 3 0 Minor capsid protein VI FYDLN_acid PF09538.10 CEP10601.1 - 9.8 6.9 24.9 1.2 9.9 7.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF724 PF05266.14 CEP10601.1 - 10 5.9 9.8 2.4 8.0 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-met PF12874.7 CEP10602.1 - 2.3e-08 34.1 21.4 4.4e-05 23.7 2.1 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP10602.1 - 0.001 19.7 28.0 0.0099 16.6 2.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CEP10602.1 - 0.002 18.4 15.9 0.35 11.2 0.1 4.3 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 CEP10602.1 - 0.0028 17.3 11.3 0.87 9.3 1.3 3.7 4 0 0 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 CEP10602.1 - 0.0053 15.4 11.0 0.029 12.9 0.2 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 CEP10602.1 - 0.0059 17.0 1.8 0.0059 17.0 1.8 4.1 4 0 0 4 4 3 1 Zinc finger, C2H2 type PHD_Oberon PF07227.11 CEP10602.1 - 0.14 12.0 4.5 1.4 8.8 0.1 3.3 4 0 0 4 4 4 0 PHD - plant homeodomain finger protein Zn_ribbon_SprT PF17283.2 CEP10602.1 - 0.15 12.0 5.3 3.9 7.5 0.4 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain LMBR1 PF04791.16 CEP10602.1 - 0.21 10.5 4.8 0.36 9.7 4.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_jaz PF12171.8 CEP10602.1 - 0.21 11.9 21.6 0.076 13.3 2.5 4.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Defensin_5 PF18251.1 CEP10602.1 - 0.29 11.3 5.5 3 8.0 0.2 2.6 2 0 0 2 2 2 0 Fungal defensin Copsin zf-Dof PF02701.15 CEP10602.1 - 0.46 10.7 5.9 7.9 6.7 0.1 3.0 3 0 0 3 3 2 0 Dof domain, zinc finger Paired_CXXCH_1 PF09699.10 CEP10602.1 - 0.59 9.9 6.3 6.4 6.6 1.6 2.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-Di19 PF05605.12 CEP10602.1 - 2.9 8.3 10.7 5 7.5 1.4 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 CEP10602.1 - 3.7 7.6 9.6 16 5.6 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbons Homeodomain PF00046.29 CEP10603.1 - 4.5e-16 58.4 3.3 8.9e-16 57.5 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP10603.1 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CEP10603.1 - 0.012 15.4 0.2 0.056 13.3 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain GerE PF00196.19 CEP10603.1 - 0.055 13.0 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Imm39 PF15568.6 CEP10604.1 - 0.64 10.1 4.5 3.6 7.7 0.0 3.3 2 1 0 3 3 3 0 Immunity protein 39 DASH_Dad1 PF08649.10 CEP10604.1 - 5.1 7.4 8.5 5.1 7.4 0.2 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad1 PAC2 PF09754.9 CEP10605.1 - 4.2e-23 82.5 0.0 5.5e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family EB1 PF03271.17 CEP10606.1 - 8.3e-17 61.2 0.9 1.7e-16 60.2 0.9 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CEP10606.1 - 2.5e-06 27.6 0.4 3.7e-06 27.1 0.4 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 CEP10606.1 - 0.11 12.6 0.2 0.21 11.8 0.2 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein Efg1 PF10153.9 CEP10607.1 - 1.3e-28 99.7 10.4 1.3e-28 99.7 10.4 1.9 2 1 0 2 2 2 1 rRNA-processing protein Efg1 Glyco_transf_92 PF01697.27 CEP10607.1 - 0.0032 17.2 1.2 0.0049 16.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Prominin PF05478.11 CEP10607.1 - 0.055 11.4 2.7 0.078 10.9 2.7 1.2 1 0 0 1 1 1 0 Prominin RWD PF05773.22 CEP10607.1 - 0.078 13.3 3.8 0.13 12.6 3.5 1.6 1 1 0 1 1 1 0 RWD domain FlaC_arch PF05377.11 CEP10607.1 - 0.26 11.7 2.9 0.95 9.9 2.9 2.1 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CEP10607.1 - 0.28 11.6 10.0 0.11 12.9 5.9 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PhoU PF01895.19 CEP10607.1 - 0.47 10.9 4.7 0.2 12.1 0.8 2.4 1 1 2 3 3 3 0 PhoU domain DUF5082 PF16888.5 CEP10607.1 - 0.54 10.5 11.7 0.087 13.1 4.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) KASH_CCD PF14662.6 CEP10607.1 - 1.1 9.1 14.9 2.4 7.9 8.6 2.4 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 CEP10607.1 - 2.3 8.4 19.8 0.23 11.6 10.7 3.1 1 1 2 3 3 3 0 Tropomyosin like Med9 PF07544.13 CEP10607.1 - 6.2 7.0 11.1 6 7.0 2.9 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SPRY PF00622.28 CEP10608.1 - 3.5e-19 69.1 0.1 6.2e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain E1-E2_ATPase PF00122.20 CEP10609.1 - 3.9e-41 140.6 0.4 3.9e-41 140.6 0.4 4.1 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP10609.1 - 1.1e-19 70.9 2.4 1.1e-19 70.9 2.4 2.6 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CEP10609.1 - 2.3e-17 62.4 0.4 6.5e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP10609.1 - 8.2e-17 61.1 0.0 1.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP10609.1 - 4.2e-14 53.3 0.0 8.2e-11 42.6 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP10609.1 - 0.0085 15.8 0.5 0.0085 15.8 0.5 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Borrelia_P13 PF05628.12 CEP10609.1 - 0.014 15.4 1.9 0.021 14.8 0.1 2.1 2 0 0 2 2 2 0 Borrelia membrane protein P13 HAD PF12710.7 CEP10609.1 - 0.04 14.3 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PAP_central PF04928.17 CEP10609.1 - 0.39 9.7 2.3 1.8 7.5 0.0 2.6 2 1 0 2 2 2 0 Poly(A) polymerase central domain PH PF00169.29 CEP10610.1 - 0.0026 18.3 2.4 0.0073 16.8 0.5 2.4 2 0 0 2 2 2 1 PH domain RNase_P_Rpp14 PF01900.19 CEP10611.1 - 4.9e-08 33.1 0.1 6.2e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family PAS_3 PF08447.12 CEP10612.1 - 7.7e-15 55.0 0.1 7.5e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 CEP10612.1 - 1.2e-07 31.7 0.0 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CEP10612.1 - 3.7e-06 27.0 0.0 9.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 CEP10612.1 - 2.4e-05 24.5 0.1 0.019 15.2 0.0 2.8 2 1 1 3 3 3 2 PAS domain PAS_4 PF08448.10 CEP10612.1 - 0.066 13.5 0.0 2.7 8.3 0.0 2.4 2 1 0 2 2 2 0 PAS fold STT3 PF02516.14 CEP10613.1 - 5.3e-155 517.1 41.5 1.1e-150 502.8 37.5 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit LidA_Long_CC PF18641.1 CEP10614.1 - 1.2e-05 25.5 0.9 1.2e-05 25.5 0.9 2.1 2 0 0 2 2 2 1 LidA long coiled-coil domain Folate_carrier PF01770.18 CEP10614.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF5638 PF18688.1 CEP10614.1 - 0.041 14.2 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Baculo_PEP_C PF04513.12 CEP10614.1 - 0.81 9.7 7.0 2.7 8.0 0.3 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ECH_2 PF16113.5 CEP10614.1 - 0.87 9.0 5.7 0.19 11.2 1.3 2.0 2 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Phasin PF05597.11 CEP10614.1 - 1.1 9.3 5.9 1 9.3 0.2 2.7 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DASH_Dam1 PF08653.10 CEP10614.1 - 6.1 6.7 7.5 2.1 8.2 0.4 3.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 Trehalase PF01204.18 CEP10615.1 - 5.1e-125 418.2 16.9 6.1e-116 388.3 7.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 CEP10615.1 - 2.1e-06 26.9 6.9 1.5e-05 24.1 6.9 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF4939 PF16297.5 CEP10617.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Hydrolase_6 PF13344.6 CEP10617.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Integrase_H2C2 PF17921.1 CEP10622.1 - 1.1e-06 28.6 0.2 1.8e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP10622.1 - 2.9e-06 27.4 0.2 5.8e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 CEP10622.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEP10623.1 - 4.9e-23 81.5 1.1 4.3e-15 55.7 0.0 3.2 4 0 0 4 4 4 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP10623.1 - 1.5e-06 27.8 0.0 5.5e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 CEP10623.1 - 0.0026 17.9 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 CEP10623.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP10623.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CEP10623.1 - 0.089 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_IclR PF09339.10 CEP10623.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4116 PF13475.6 CEP10623.1 - 0.2 11.4 0.8 5.4 6.8 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4116) RT_RNaseH_2 PF17919.1 CEP10625.1 - 4.7e-29 100.4 0.1 5.4e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10625.1 - 1.7e-18 66.8 0.0 2.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pepsin-I3 PF06394.13 CEP10625.1 - 0.17 12.1 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Retrotrans_gag PF03732.17 CEP10626.1 - 1.4e-15 57.3 0.0 2.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Mpv17_PMP22 PF04117.12 CEP10627.1 - 4.7e-18 65.2 1.7 7.5e-18 64.5 0.5 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family SesA PF17107.5 CEP10628.1 - 0.067 13.4 0.0 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NCBP3 PF10309.9 CEP10628.1 - 0.13 12.2 0.3 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 MRC1 PF09444.10 CEP10629.1 - 3.3e-23 82.8 13.1 3.3e-23 82.8 13.1 7.8 4 2 3 7 7 7 1 MRC1-like domain RFamide_26RFa PF11109.8 CEP10629.1 - 0.054 14.0 0.5 0.054 14.0 0.5 3.5 3 0 0 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 RasGEF PF00617.19 CEP10630.1 - 8.5e-51 172.7 2.0 2.6e-50 171.1 2.0 1.9 1 0 0 1 1 1 1 RasGEF domain RNR_Alpha PF17975.1 CEP10630.1 - 0.07 13.6 0.3 0.07 13.6 0.3 2.8 3 0 0 3 3 3 0 Ribonucleotide reductase alpha domain NOA36 PF06524.12 CEP10630.1 - 0.22 10.8 24.5 0.086 12.1 13.4 2.6 2 0 0 2 2 2 0 NOA36 protein CobT PF06213.12 CEP10631.1 - 0.011 15.2 15.4 0.012 15.0 15.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 CEP10631.1 - 0.014 13.7 24.7 0.015 13.5 24.7 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 CEP10631.1 - 0.018 15.0 16.8 0.022 14.7 16.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 CEP10631.1 - 0.074 12.8 24.1 0.093 12.4 24.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CEP10631.1 - 0.092 11.0 21.1 0.1 10.9 21.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 CEP10631.1 - 0.1 12.9 27.1 0.14 12.4 27.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 CEP10631.1 - 0.23 10.7 31.9 0.32 10.3 31.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CEP10631.1 - 0.3 9.1 38.4 0.41 8.7 38.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 CEP10631.1 - 0.42 9.1 21.7 0.52 8.8 21.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CBP4 PF07960.11 CEP10631.1 - 0.71 9.7 4.8 0.99 9.3 4.8 1.2 1 0 0 1 1 1 0 CBP4 BUD22 PF09073.10 CEP10631.1 - 0.94 8.8 20.7 1.1 8.5 20.7 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 CEP10631.1 - 2.1 8.1 16.2 3.7 7.3 16.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rhabdo_ncap PF00945.18 CEP10631.1 - 2.4 6.9 10.2 2.7 6.8 10.2 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4820 PF16091.5 CEP10631.1 - 3.6 6.9 6.1 5 6.4 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TFIIA PF03153.13 CEP10631.1 - 3.7 7.5 18.9 3.5 7.5 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 CEP10631.1 - 4.2 6.7 29.4 5.2 6.4 29.4 1.1 1 0 0 1 1 1 0 SDA1 THOC2_N PF16134.5 CEP10631.1 - 4.7 5.7 10.6 5.9 5.4 10.6 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Vfa1 PF08432.10 CEP10631.1 - 5.2 7.4 16.0 7.6 6.8 16.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_A_exo1 PF01612.20 CEP10632.1 - 0.009 15.7 0.0 0.029 14.1 0.0 1.8 1 1 1 2 2 2 1 3'-5' exonuclease zf-RING_4 PF14570.6 CEP10633.1 - 0.031 14.1 0.2 0.031 14.1 0.2 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Helitron_like_N PF14214.6 CEP10635.1 - 6.9e-63 212.3 0.0 1e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP10636.1 - 7.5e-12 45.1 0.0 9.2e-12 44.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase SLS PF14611.6 CEP10638.1 - 2.4e-15 57.0 3.0 5.2e-15 55.9 3.0 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 CEP10638.1 - 1.1e-07 31.5 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CEP10638.1 - 0.13 12.1 0.5 11 5.9 0.0 2.6 2 0 0 2 2 2 0 KH domain EF-hand_1 PF00036.32 CEP10639.1 - 8.1e-19 65.7 10.2 1.4e-09 36.8 0.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CEP10639.1 - 2e-14 53.8 2.3 2e-14 53.8 2.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CEP10639.1 - 7.4e-13 47.3 8.1 1.2e-08 34.2 0.3 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CEP10639.1 - 8e-12 44.1 6.8 5.7e-07 28.7 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEP10639.1 - 8.6e-11 41.5 8.7 2.4e-08 33.7 1.8 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CEP10639.1 - 1.5e-05 24.8 4.9 0.00013 21.9 2.0 2.8 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEP10639.1 - 0.00028 21.2 1.1 0.00056 20.2 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP10639.1 - 0.00077 19.8 0.3 0.0011 19.2 0.3 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 CEP10639.1 - 0.02 14.9 0.0 0.061 13.3 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB Dockerin_1 PF00404.18 CEP10639.1 - 0.055 13.7 1.6 0.13 12.4 1.4 1.7 1 1 1 2 2 2 0 Dockerin type I domain EF-hand_11 PF08976.11 CEP10639.1 - 0.074 13.9 0.0 0.091 13.6 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CEP10640.1 - 3.5e-30 101.3 4.7 9.9e-08 31.0 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP10640.1 - 1.9e-26 92.3 5.9 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP10640.1 - 1.5e-21 74.4 5.3 3.8e-05 23.3 0.5 5.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEP10640.1 - 1e-19 70.1 5.2 1.7e-07 30.9 0.0 3.8 2 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEP10640.1 - 1.1e-18 65.8 10.1 2.9e-06 26.5 0.1 5.7 4 2 2 6 6 6 3 EF hand EF-hand_4 PF12763.7 CEP10640.1 - 2.5e-10 40.2 2.9 3.6e-05 23.6 0.2 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEP10640.1 - 4.3e-07 30.2 0.1 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP10640.1 - 2.9e-06 27.6 5.1 0.00049 20.4 2.2 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CEP10640.1 - 0.0018 18.4 0.1 7.6 6.8 0.0 3.7 2 1 1 3 3 3 1 Dockerin type I domain TerB PF05099.13 CEP10640.1 - 0.008 16.1 1.5 3.7 7.5 0.2 3.0 1 1 2 3 3 3 1 Tellurite resistance protein TerB Cbl_N2 PF02761.14 CEP10640.1 - 0.013 16.2 1.8 0.25 12.1 0.1 2.4 1 1 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Adenine_glyco PF03352.13 CEP10640.1 - 0.021 14.6 1.2 0.03 14.1 0.6 1.5 1 1 1 2 2 2 0 Methyladenine glycosylase Caleosin PF05042.13 CEP10640.1 - 0.026 14.4 1.2 0.52 10.2 0.1 2.6 2 1 0 3 3 3 0 Caleosin related protein EF-hand_14 PF17959.1 CEP10640.1 - 0.037 14.4 1.4 0.35 11.2 1.4 2.4 1 1 0 1 1 1 0 EF-hand domain RNB PF00773.19 CEP10640.1 - 0.04 13.2 0.5 3.3 7.0 0.0 2.1 1 1 1 2 2 2 0 RNB domain DUF1636 PF07845.11 CEP10640.1 - 0.042 14.3 0.0 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) PIN_4 PF13638.6 CEP10640.1 - 0.11 12.8 0.5 0.14 12.4 0.5 1.2 1 0 0 1 1 1 0 PIN domain VCBS PF13517.6 CEP10640.1 - 0.14 12.8 0.8 51 4.6 1.5 3.0 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Serglycin PF04360.12 CEP10641.1 - 0.0062 16.5 2.6 0.017 15.1 2.6 1.7 1 0 0 1 1 1 1 Serglycin DUF5083 PF16890.5 CEP10641.1 - 0.2 11.4 3.0 0.35 10.6 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) KASH PF10541.9 CEP10641.1 - 0.71 10.2 3.7 0.6 10.4 0.1 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain Ost5 PF05251.12 CEP10641.1 - 1.5 9.1 8.7 2.2 8.6 0.8 3.5 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 Claudin_2 PF13903.6 CEP10641.1 - 6.3 6.5 15.7 0.64 9.7 5.7 3.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Rota_NSP3 PF01665.16 CEP10643.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Ribosomal_L31e PF01198.19 CEP10645.1 - 5e-37 126.0 2.3 6.3e-37 125.7 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e ERAP1_C PF11838.8 CEP10645.1 - 0.026 14.1 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain NDC10_II PF16787.5 CEP10646.1 - 1.7e-08 33.9 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Baculo_PEP_C PF04513.12 CEP10646.1 - 0.026 14.6 1.0 0.069 13.2 1.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LETM1 PF07766.13 CEP10647.1 - 3.2e-107 357.8 1.9 3.2e-107 357.8 1.9 3.0 2 1 2 4 4 4 1 LETM1-like protein DUF3232 PF11554.8 CEP10647.1 - 0.00041 20.7 0.6 0.00041 20.7 0.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3232) SAP PF02037.27 CEP10647.1 - 0.0048 16.6 0.4 0.062 13.1 0.0 3.1 4 0 0 4 4 4 1 SAP domain HycH PF07450.11 CEP10647.1 - 0.043 14.2 0.7 0.21 11.9 0.7 2.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH DUF2459 PF09601.10 CEP10647.1 - 0.15 11.8 0.2 0.38 10.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) ThiF PF00899.21 CEP10648.1 - 1.5e-69 234.0 0.6 3.9e-69 232.7 0.1 1.7 2 0 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.9 CEP10648.1 - 5.8e-10 39.5 7.3 5.6e-07 29.7 0.2 3.3 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CEP10648.1 - 2.8e-07 31.0 0.3 2.8e-07 31.0 0.3 2.5 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 CEP10648.1 - 1e-05 25.9 0.3 6.6e-05 23.3 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CEP10648.1 - 0.00044 20.3 2.1 0.00051 20.1 0.1 2.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CEP10648.1 - 0.0033 17.7 1.0 0.04 14.2 1.0 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CEP10648.1 - 0.057 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain AhpC-TSA PF00578.21 CEP10649.1 - 0.0087 16.0 0.1 0.42 10.5 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family ARPC4 PF05856.12 CEP10651.1 - 6.1e-82 273.2 4.4 6.8e-82 273.0 4.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 CEP10651.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Sm_like domain Octopine_DH PF02317.17 CEP10651.1 - 0.11 12.6 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain LAG1-DNAbind PF09271.11 CEP10652.1 - 3.1e-47 161.0 0.2 3.1e-47 161.0 0.2 3.5 4 1 0 4 4 4 1 LAG1, DNA binding BTD PF09270.10 CEP10652.1 - 3e-23 82.8 2.5 1e-21 77.7 2.5 3.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain TFIIA PF03153.13 CEP10652.1 - 0.0024 18.0 27.0 0.0047 17.0 12.6 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEP10652.1 - 0.0056 16.3 24.3 0.041 13.5 12.1 3.6 3 1 0 3 3 3 2 Spt20 family TIG PF01833.24 CEP10652.1 - 0.015 15.4 0.0 0.082 13.0 0.0 2.3 1 0 0 1 1 1 0 IPT/TIG domain ANAPC_CDC26 PF10471.9 CEP10652.1 - 0.2 12.5 15.6 0.4 11.5 6.7 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 RNA_pol_Rbc25 PF08292.12 CEP10652.1 - 0.33 11.2 2.6 1.4 9.2 2.6 2.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Arrestin_C PF02752.22 CEP10652.1 - 0.55 10.7 4.2 4 7.9 2.1 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Roughex PF06020.11 CEP10652.1 - 0.72 8.9 9.2 0.051 12.7 3.5 1.9 2 0 0 2 2 2 0 Drosophila roughex protein tRNA_anti-codon PF01336.25 CEP10653.1 - 7.3e-11 41.9 0.1 2.8e-10 40.1 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF2110 PF09883.9 CEP10653.1 - 0.05 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) RMI2 PF16100.5 CEP10653.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 SSB PF00436.25 CEP10653.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Single-strand binding protein family CH PF00307.31 CEP10654.1 - 2.4e-28 98.5 0.4 2.6e-13 50.1 0.0 3.3 2 0 0 2 2 2 2 Calponin homology (CH) domain GAS2 PF02187.17 CEP10654.1 - 7e-11 42.1 0.0 5.2e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.8 CEP10654.1 - 0.00019 21.2 0.0 0.0013 18.5 0.0 2.5 1 0 0 1 1 1 1 CAMSAP CH domain ALS2CR8 PF15299.6 CEP10654.1 - 0.0053 16.7 0.9 0.028 14.3 0.9 2.3 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 YvrJ PF12841.7 CEP10654.1 - 0.3 10.7 1.9 7.1 6.3 0.0 3.8 3 0 0 3 3 3 0 YvrJ protein family DUF4874 PF16173.5 CEP10654.1 - 2.6 7.7 5.3 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4874) NLRC4_HD2 PF17776.1 CEP10654.1 - 3.1 8.4 7.7 0.85 10.2 0.4 3.9 3 0 0 3 3 3 0 NLRC4 helical domain HD2 PhoD PF09423.10 CEP10655.1 - 1.8e-05 23.9 0.1 0.019 14.0 0.0 3.0 3 0 0 3 3 3 2 PhoD-like phosphatase Mpp10 PF04006.12 CEP10656.1 - 0.056 11.9 29.8 0.081 11.4 29.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Myb_DNA-binding PF00249.31 CEP10656.1 - 0.075 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SDA1 PF05285.12 CEP10656.1 - 0.21 11.0 27.6 0.024 14.0 23.1 1.7 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CEP10656.1 - 6.3 4.9 31.9 11 4.1 31.9 1.3 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 CEP10656.1 - 6.9 6.3 19.7 12 5.5 19.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BSP_II PF05432.11 CEP10656.1 - 7.8 6.1 29.8 22 4.6 29.9 1.6 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sybindin PF04099.12 CEP10657.1 - 6.2e-23 81.3 0.4 1.3e-22 80.3 0.4 1.5 1 1 0 1 1 1 1 Sybindin-like family KIAA1430 PF13879.6 CEP10659.1 - 0.018 15.8 0.2 0.028 15.2 0.2 1.3 1 0 0 1 1 1 0 KIAA1430 homologue XhlA PF10779.9 CEP10659.1 - 0.71 10.1 2.4 1.2 9.3 2.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Sel1 PF08238.12 CEP10660.1 - 4.3e-29 100.3 26.8 1.9e-08 34.7 0.3 7.9 8 0 0 8 8 8 6 Sel1 repeat EF-hand_like PF09279.11 CEP10661.1 - 0.036 14.5 0.2 0.067 13.7 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Dynein_light PF01221.18 CEP10661.1 - 0.1 13.0 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 Ras PF00071.22 CEP10663.1 - 6.4e-58 194.9 0.2 7.6e-58 194.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP10663.1 - 8.5e-33 113.1 0.0 1.3e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP10663.1 - 8.8e-15 54.6 0.0 1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP10663.1 - 9.5e-08 32.1 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP10663.1 - 2.3e-07 30.4 0.1 3.1e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP10663.1 - 2.8e-06 27.0 0.1 6.4e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP10663.1 - 5.6e-05 23.1 0.2 0.0035 17.3 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CEP10663.1 - 0.00084 19.0 0.0 0.0032 17.1 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CEP10663.1 - 0.0032 17.2 0.2 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CEP10663.1 - 0.0043 17.4 0.0 0.0076 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 CEP10663.1 - 0.0081 16.0 0.4 0.24 11.2 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 CEP10663.1 - 0.0091 15.3 0.9 0.037 13.3 0.1 2.1 2 1 0 2 2 2 1 Septin NTPase_1 PF03266.15 CEP10663.1 - 0.01 15.8 0.1 0.019 14.9 0.0 1.5 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 CEP10663.1 - 0.019 14.5 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CEP10663.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CEP10663.1 - 0.021 14.6 0.1 0.057 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CEP10663.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 CEP10663.1 - 0.05 13.5 0.3 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CEP10663.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CEP10663.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 CEP10663.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CEP10663.1 - 0.34 10.0 2.0 1.4 8.0 0.2 2.2 1 1 0 2 2 2 0 G-protein alpha subunit Sod_Fe_C PF02777.18 CEP10664.1 - 3.2e-40 136.4 0.8 4.5e-40 135.9 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CEP10664.1 - 1.4e-30 105.6 3.1 3e-30 104.5 3.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Alk_phosphatase PF00245.20 CEP10665.1 - 2.7e-99 333.0 0.1 3.2e-99 332.7 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CEP10665.1 - 0.0045 16.4 0.0 0.015 14.7 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Phage_integrase PF00589.22 CEP10666.1 - 2.6e-07 30.6 0.0 6.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.6 CEP10666.1 - 0.003 17.4 0.7 0.0063 16.3 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Phage_int_SAM_4 PF13495.6 CEP10666.1 - 0.045 14.2 0.0 0.17 12.4 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF2790 PF10976.8 CEP10667.1 - 0.047 13.7 0.6 0.063 13.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) RasGAP PF00616.19 CEP10668.1 - 1.4e-27 96.8 4.3 1.2e-18 67.6 0.1 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CEP10668.1 - 1.9e-18 67.0 0.1 5.9e-18 65.3 0.1 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CEP10668.1 - 1.1e-07 31.8 0.4 2.9e-07 30.3 0.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain Cnd1 PF12717.7 CEP10668.1 - 0.00051 20.1 0.3 0.011 15.7 0.1 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.6 CEP10668.1 - 0.0045 16.9 0.5 0.052 13.4 0.0 3.2 3 0 0 3 3 3 1 Cell morphogenesis C-terminal HEAT PF02985.22 CEP10668.1 - 0.0063 16.7 1.7 0.039 14.2 0.3 3.3 2 0 0 2 2 2 1 HEAT repeat RPM2 PF08579.11 CEP10668.1 - 0.14 12.5 0.9 66 3.9 0.1 4.0 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Peptidase_M13_N PF05649.13 CEP10669.1 - 8.1e-93 312.1 0.0 1e-92 311.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEP10669.1 - 6.6e-66 221.8 0.3 5.3e-65 218.9 0.1 2.1 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M48 PF01435.18 CEP10669.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 RVT_1 PF00078.27 CEP10670.1 - 9.9e-26 90.6 0.0 1.9e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP10670.1 - 5.4e-11 42.4 0.0 1.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP10670.1 - 0.00057 19.5 0.7 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family CCDC-167 PF15188.6 CEP10670.1 - 0.031 14.6 4.1 0.075 13.4 4.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Jnk-SapK_ap_N PF09744.9 CEP10670.1 - 0.36 11.1 7.6 0.27 11.5 5.5 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 CEP10670.1 - 0.47 10.7 5.7 0.99 9.6 5.7 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Muted PF14942.6 CEP10670.1 - 1 9.7 4.8 1.9 8.8 4.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein WGR PF05406.15 CEP10670.1 - 3 7.9 5.5 4.4 7.4 3.2 2.1 2 0 0 2 2 2 0 WGR domain Csm1_N PF18504.1 CEP10670.1 - 3.2 8.2 8.0 12 6.4 8.0 1.9 1 1 0 1 1 1 0 Csm1 N-terminal domain Phage_integrase PF00589.22 CEP10671.1 - 0.00068 19.5 0.2 0.0017 18.2 0.2 1.7 1 1 0 1 1 1 1 Phage integrase family DUF1836 PF08876.11 CEP10671.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) RT_RNaseH_2 PF17919.1 CEP10672.1 - 4.2e-25 87.7 0.1 1e-24 86.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10672.1 - 2.6e-20 72.6 0.1 8.1e-20 71.1 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP10672.1 - 9.2e-06 25.3 0.1 2.6e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3843 PF12954.7 CEP10675.1 - 0.048 12.6 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) DUF4735 PF15882.5 CEP10677.1 - 0.067 12.6 0.6 0.087 12.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) DUF202 PF02656.15 CEP10680.1 - 1.5e-21 76.6 0.4 1.5e-21 76.6 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Ribosomal_L19e PF01280.20 CEP10680.1 - 0.056 13.5 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L19e YtpI PF14007.6 CEP10680.1 - 0.76 10.0 6.7 0.4 10.9 3.1 2.2 2 0 0 2 2 2 0 YtpI-like protein Cg6151-P PF10233.9 CEP10682.1 - 6.6e-05 23.2 0.2 7.4e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P HLH PF00010.26 CEP10683.1 - 1.8e-11 43.8 3.6 1.9e-11 43.7 2.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 CEP10683.1 - 0.0084 15.7 1.5 0.0084 15.7 1.5 2.5 2 1 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Strep_pep PF14404.6 CEP10683.1 - 0.15 12.4 1.5 0.32 11.3 1.5 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species SlyX PF04102.12 CEP10683.1 - 0.18 12.5 2.1 1.1 10.0 0.6 2.7 2 0 0 2 2 2 0 SlyX MctB PF11382.8 CEP10683.1 - 0.25 11.0 9.7 0.37 10.5 0.4 2.2 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DivIC PF04977.15 CEP10683.1 - 0.52 10.1 6.0 0.1 12.4 1.9 2.1 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 CEP10683.1 - 3.5 8.3 10.0 0.38 11.4 2.6 2.6 2 1 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 CEP10683.1 - 3.9 7.8 7.4 0.5 10.6 2.3 2.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper FUSC_2 PF13515.6 CEP10684.1 - 1.4e-17 63.9 11.0 1.4e-17 63.9 11.0 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CEP10684.1 - 7.3e-17 61.3 14.2 3.4e-15 55.8 0.9 2.9 3 0 0 3 3 3 2 Aluminium activated malate transporter ArAE_2_N PF10337.9 CEP10684.1 - 6.9e-14 51.7 0.5 1.6e-13 50.6 0.2 1.7 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CEP10684.1 - 2.1e-10 40.8 5.6 6.4e-10 39.2 2.5 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 CEP10684.1 - 3.5e-07 29.2 17.2 2.6e-06 26.3 12.3 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein family PARP_reg PF02877.14 CEP10684.1 - 0.019 15.1 0.1 0.057 13.5 0.1 1.9 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain Erf4 PF10256.9 CEP10684.1 - 0.092 12.9 0.1 13 5.9 0.0 3.7 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family PTPS_related PF10131.9 CEP10684.1 - 0.13 10.6 11.0 0.17 10.2 3.5 2.2 1 1 1 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Zn_Tnp_IS1 PF03811.13 CEP10684.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 InsA N-terminal domain ArAE_1 PF06081.11 CEP10684.1 - 9.9 6.3 11.8 0.51 10.5 4.3 2.3 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 RasGEF PF00617.19 CEP10685.1 - 4.6e-32 111.6 0.3 1.5e-18 67.6 0.0 2.8 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 CEP10685.1 - 5.3e-16 58.7 3.7 1.7e-15 57.1 3.7 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Snapin_Pallidin PF14712.6 CEP10685.1 - 0.05 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Snapin/Pallidin Pex24p PF06398.11 CEP10686.1 - 2.6e-12 46.4 2.1 2.6e-12 46.4 2.1 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.6 CEP10686.1 - 0.00088 19.5 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) DUF3395 PF11875.8 CEP10686.1 - 0.1 12.5 1.6 0.24 11.3 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) Tom37 PF10568.9 CEP10687.1 - 5.6e-35 120.4 0.3 9.5e-35 119.6 0.3 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CEP10687.1 - 7.1e-21 74.8 0.0 1.3e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CEP10687.1 - 1.6e-17 63.0 0.1 3.5e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP10687.1 - 1.1e-07 31.8 0.0 5.6e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP10687.1 - 0.013 15.7 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP10687.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IP_trans PF02121.18 CEP10688.1 - 3.8e-94 314.9 4.9 4.6e-94 314.6 4.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF1712 PF08217.11 CEP10689.1 - 4.2e-33 114.7 10.0 1.2e-27 96.7 0.1 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF4396 PF14342.6 CEP10690.1 - 2.9e-28 99.0 3.9 3.1e-28 98.9 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Polysacc_synt_C PF14667.6 CEP10690.1 - 0.14 12.2 1.2 1.6 8.8 0.1 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain ParA PF10609.9 CEP10692.1 - 5.1e-100 334.0 0.0 5.9e-100 333.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CEP10692.1 - 1.5e-09 38.0 0.0 4.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEP10692.1 - 3.9e-08 33.4 1.8 5.9e-07 29.6 1.8 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CEP10692.1 - 9.3e-07 28.4 0.0 2.3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 CEP10692.1 - 5e-05 22.4 0.6 7.2e-05 21.9 0.6 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 CEP10692.1 - 0.00011 21.5 2.0 0.00022 20.5 1.3 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CEP10692.1 - 0.00017 21.2 0.1 0.00055 19.5 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 CEP10692.1 - 0.0067 15.9 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 CEP10692.1 - 0.0071 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CEP10692.1 - 0.0085 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CLP1_P PF16575.5 CEP10692.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 CEP10692.1 - 0.017 14.9 0.1 3.7 7.3 0.5 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CEP10692.1 - 0.078 12.6 0.1 0.3 10.7 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CEP10692.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 CEP10692.1 - 0.27 11.0 0.2 0.48 10.1 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CEP10692.1 - 0.41 10.5 2.1 0.79 9.6 2.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Dus PF01207.17 CEP10693.1 - 6.9e-68 229.0 0.0 9.5e-67 225.3 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 CEP10693.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 CEP10693.1 - 0.011 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 CEP10693.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 CEP10693.1 - 0.026 13.7 0.0 0.2 10.8 0.0 1.9 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 CEP10693.1 - 0.095 12.1 0.0 0.25 10.7 0.0 1.5 1 1 0 2 2 2 0 Nitronate monooxygenase W2 PF02020.18 CEP10694.1 - 0.0016 18.5 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RT_RNaseH PF17917.1 CEP10695.1 - 0.14 12.4 0.0 0.65 10.3 0.0 2.0 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase OrfB_Zn_ribbon PF07282.11 CEP10696.1 - 4.4e-09 36.1 1.3 8.1e-09 35.3 1.3 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Cytochrome_C7 PF14522.6 CEP10696.1 - 0.015 15.2 1.9 0.035 14.1 1.9 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c HalOD2 PF18547.1 CEP10696.1 - 0.67 9.9 2.7 11 6.1 0.3 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 Retrotrans_gag PF03732.17 CEP10697.1 - 0.029 14.6 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein TPD52 PF04201.15 CEP10697.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Tumour protein D52 family Orbi_NS3 PF01616.16 CEP10699.1 - 0.17 11.5 0.4 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 Orbivirus NS3 DUF4811 PF16069.5 CEP10700.1 - 0.0034 17.3 0.6 0.0042 17.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4811) MerR_1 PF13411.6 CEP10700.1 - 0.03 14.4 0.2 0.18 11.9 0.2 2.1 1 1 1 2 2 2 0 MerR HTH family regulatory protein RVT_1 PF00078.27 CEP10701.1 - 8e-23 81.1 0.0 1.1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 CEP10703.1 - 3.2e-14 52.9 0.0 4.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Act-Frag_cataly PF09192.10 CEP10704.1 - 0.096 12.0 1.2 0.15 11.4 1.2 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic PBSX_XtrA PF17356.2 CEP10704.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA PIF1 PF05970.14 CEP10706.1 - 3.4e-35 121.9 0.0 2.9e-33 115.5 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP10706.1 - 1.7e-15 57.2 0.0 9.8e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP10706.1 - 6.2e-10 39.6 0.0 3.2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP10706.1 - 6.5e-09 36.2 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP10706.1 - 0.00016 21.5 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP10706.1 - 0.00018 21.4 0.2 0.43 10.3 0.0 2.7 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CEP10706.1 - 0.00025 20.9 0.2 0.0038 17.0 0.2 2.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 CEP10706.1 - 0.00038 20.1 1.2 0.0018 18.0 0.4 2.3 1 1 2 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP10706.1 - 0.00068 20.0 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 CEP10706.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein DUF2075 PF09848.9 CEP10706.1 - 0.0027 17.0 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 CEP10706.1 - 0.005 16.0 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CEP10706.1 - 0.0052 17.3 0.0 0.0084 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 CEP10706.1 - 0.0091 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Septin NTPase_1 PF03266.15 CEP10706.1 - 0.013 15.5 0.0 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 CEP10706.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 CEP10706.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEP10706.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CEP10706.1 - 0.025 13.9 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 CEP10706.1 - 0.026 14.6 0.2 0.29 11.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEP10706.1 - 0.027 14.6 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 CEP10706.1 - 0.028 14.1 0.0 0.11 12.2 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CEP10706.1 - 0.029 14.9 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Herpes_Helicase PF02689.14 CEP10706.1 - 0.029 12.3 0.0 0.051 11.5 0.0 1.3 1 0 0 1 1 1 0 Helicase MeaB PF03308.16 CEP10706.1 - 0.036 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 CEP10706.1 - 0.04 14.4 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CEP10706.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CEP10706.1 - 0.048 13.6 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 RsgA GTPase IIGP PF05049.13 CEP10706.1 - 0.05 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 CEP10706.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 CEP10706.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.15 CEP10706.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 CEP10706.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 CEP10707.1 - 0.00086 19.3 0.9 0.0015 18.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle HAD_SAK_1 PF10307.9 CEP10709.1 - 3.8e-61 206.5 0.0 5.3e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Ion_trans PF00520.31 CEP10710.1 - 1.1e-26 93.6 24.7 1.6e-26 93.1 24.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CEP10710.1 - 5.8e-10 39.0 11.3 5.8e-10 39.0 11.3 2.9 2 1 1 3 3 3 1 Ion channel DnaJ PF00226.31 CEP10711.1 - 6e-21 74.3 3.9 6e-21 74.3 3.9 2.6 1 1 1 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CEP10711.1 - 6.3e-20 69.6 5.3 0.049 13.8 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10711.1 - 3.6e-18 64.5 6.3 0.00031 20.5 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP10711.1 - 5.6e-12 46.0 12.6 0.0006 20.3 0.1 6.3 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEP10711.1 - 3.3e-11 43.6 3.0 9.3e-06 26.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP10711.1 - 4e-11 42.2 7.7 0.053 13.8 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP10711.1 - 1.3e-09 38.1 8.7 0.037 14.8 0.1 6.9 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP10711.1 - 1.3e-09 37.5 3.8 0.007 16.0 0.0 5.1 3 2 2 5 5 5 3 TPR repeat TPR_9 PF13371.6 CEP10711.1 - 2.5e-09 37.2 7.8 0.088 13.0 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP10711.1 - 1.1e-08 34.8 3.3 0.0011 19.2 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP10711.1 - 3.1e-06 27.3 10.7 0.37 11.0 0.0 5.0 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEP10711.1 - 6.8e-05 23.3 12.6 2.3 9.0 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 CEP10711.1 - 0.00086 18.1 0.6 0.097 11.4 0.0 2.9 2 2 1 4 4 4 1 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 CEP10711.1 - 0.0023 18.4 1.8 2.2 8.7 0.0 3.3 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 CEP10711.1 - 0.0024 18.2 14.7 0.78 10.1 0.1 5.6 2 2 3 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP10711.1 - 0.0031 17.8 7.8 2.5 8.4 0.0 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP10711.1 - 0.0034 17.4 1.3 0.77 9.9 0.1 3.9 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEP10711.1 - 0.0058 16.6 9.0 8.9 6.6 0.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat SLT_L PF14718.6 CEP10711.1 - 0.039 14.1 1.4 9.5 6.4 0.1 3.6 2 1 1 3 3 3 0 Soluble lytic murein transglycosylase L domain SesA PF17107.5 CEP10711.1 - 0.18 12.0 7.2 17 5.6 2.0 3.8 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 CEP10711.1 - 0.21 11.5 1.6 1 9.3 0.1 3.1 3 0 0 3 3 1 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 CEP10711.1 - 0.78 10.4 10.4 2.3 8.9 0.1 4.2 3 1 0 4 4 3 0 Cytochrome b562 ABC_tran_Xtn PF12848.7 CEP10711.1 - 8.9 6.4 14.4 0.81 9.8 0.4 3.3 3 0 0 3 3 3 0 ABC transporter BLOC1_2 PF10046.9 CEP10711.1 - 9.9 6.5 14.6 0.73 10.2 0.7 3.8 5 0 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkinase PF00069.25 CEP10712.1 - 1.2e-52 178.9 0.1 3.9e-52 177.2 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10712.1 - 2.9e-22 79.2 0.0 5.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP10712.1 - 0.0014 18.6 0.1 0.0029 17.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEP10712.1 - 0.014 15.0 0.1 0.014 15.0 0.1 1.7 2 0 0 2 2 2 0 RIO1 family SGT1 PF07093.11 CEP10712.1 - 0.038 12.4 0.1 0.051 12.0 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein Choline_kinase PF01633.20 CEP10712.1 - 0.095 12.3 0.9 0.32 10.6 0.2 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase ADH_zinc_N PF00107.26 CEP10713.1 - 2.2e-34 118.2 0.0 3.3e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP10713.1 - 6.3e-12 46.7 0.0 1.2e-11 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP10713.1 - 1e-07 31.8 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CEP10713.1 - 0.003 16.9 0.4 0.0049 16.2 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CEP10713.1 - 0.0094 16.2 0.1 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 CEP10713.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase GTP_EFTU PF00009.27 CEP10714.1 - 1.5e-44 151.9 0.0 3e-44 150.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP10714.1 - 5.6e-32 110.4 0.8 3.5e-31 107.8 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEP10714.1 - 3.2e-10 40.2 0.2 7.2e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEP10714.1 - 0.003 17.6 0.2 0.037 14.1 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 CEP10714.1 - 0.029 14.6 0.2 0.084 13.2 0.2 1.8 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain LPD34 PF18852.1 CEP10714.1 - 0.047 13.3 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Iso_dh PF00180.20 CEP10715.1 - 2.6e-84 283.4 0.0 3.1e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ART-PolyVal PF18760.1 CEP10715.1 - 0.012 16.7 0.1 0.028 15.5 0.1 1.6 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins zf-CCHC PF00098.23 CEP10717.1 - 0.00085 19.3 0.9 0.0015 18.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 CEP10719.1 - 1.6e-17 63.8 0.0 2.5e-17 63.1 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.6 CEP10720.1 - 7.1e-20 71.2 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 CEP10720.1 - 0.0052 17.0 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain PIN_4 PF13638.6 CEP10721.1 - 1.5e-21 77.0 0.1 5.5e-21 75.2 0.1 2.0 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 CEP10721.1 - 1.9e-08 34.1 0.6 5.1e-08 32.7 0.6 1.8 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Utp12 PF04003.12 CEP10722.1 - 3.9e-23 81.8 0.0 7.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CEP10722.1 - 7.2e-08 32.6 1.4 0.046 14.0 0.0 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP10722.1 - 4.6e-05 24.1 1.6 0.03 15.2 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat CSTF2_hinge PF14327.6 CEP10722.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 PLDc PF00614.22 CEP10723.1 - 8.5e-17 60.6 2.0 9.6e-10 38.2 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEP10723.1 - 2.7e-16 59.6 0.1 3.1e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PUF PF00806.19 CEP10723.1 - 0.024 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DDE_Tnp_IS66_C PF13817.6 CEP10723.1 - 0.08 13.2 1.0 2.4 8.4 0.0 3.4 3 0 0 3 3 3 0 IS66 C-terminal element Mg_trans_NIPA PF05653.14 CEP10725.1 - 4.3e-81 272.3 20.8 5.2e-81 272.0 20.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CEP10725.1 - 8e-07 29.3 5.2 8e-07 29.3 5.2 2.6 2 1 0 2 2 2 1 EamA-like transporter family YibE_F PF07907.11 CEP10725.1 - 0.0022 17.6 4.1 0.0022 17.6 4.1 2.6 2 1 1 3 3 3 1 YibE/F-like protein DUF3360 PF11840.8 CEP10725.1 - 0.08 11.7 6.1 0.017 13.9 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3360) DUF2937 PF11157.8 CEP10725.1 - 0.16 11.7 1.0 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Helitron_like_N PF14214.6 CEP10730.1 - 5.4e-38 131.1 0.0 1.8e-37 129.4 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DnaJ_CXXCXGXG PF00684.19 CEP10730.1 - 0.027 14.8 7.0 0.25 11.7 0.7 2.6 1 1 0 1 1 1 0 DnaJ central domain zinc_ribbon_9 PF14369.6 CEP10730.1 - 0.27 11.5 2.8 27 5.1 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon Prok-RING_1 PF14446.6 CEP10730.1 - 0.34 10.9 8.1 0.36 10.8 0.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 CEP10730.1 - 0.53 9.8 2.9 21 4.7 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CEP10730.1 - 1.3 9.0 3.5 14 5.7 0.6 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain RuBisCO_large_N PF02788.16 CEP10732.1 - 0.13 12.5 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain UvrD_C PF13361.6 CEP10733.1 - 3.9e-05 23.2 0.0 4.4e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HTH_28 PF13518.6 CEP10735.1 - 5.4e-05 23.2 0.0 8.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP10735.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP10735.1 - 0.0025 17.2 0.0 0.0058 16.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 CEP10735.1 - 0.0087 16.1 0.1 0.02 14.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix PAX PF00292.18 CEP10735.1 - 0.057 13.3 0.0 0.074 13.0 0.0 1.3 1 1 0 1 1 1 0 'Paired box' domain CENP-B_N PF04218.13 CEP10735.1 - 0.076 12.7 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 CEP10735.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 RasGEF PF00617.19 CEP10736.1 - 2.7e-50 171.0 2.0 8.6e-50 169.4 2.0 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP10736.1 - 7.7e-13 48.6 12.1 8.1e-13 48.5 1.9 3.4 3 0 0 3 3 3 2 RasGEF N-terminal motif EF-hand_1 PF00036.32 CEP10737.1 - 1.8e-33 111.6 14.4 1.5e-08 33.6 0.4 4.8 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEP10737.1 - 5.8e-29 100.4 10.2 1.1e-14 54.6 2.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP10737.1 - 8.7e-25 84.5 9.5 1.9e-06 27.3 0.1 4.8 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CEP10737.1 - 7.3e-24 82.2 16.6 4.5e-08 32.2 0.1 5.1 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 CEP10737.1 - 1.6e-17 63.1 13.2 1.1e-08 34.7 2.0 3.8 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEP10737.1 - 3.8e-11 43.3 4.5 5.4e-06 26.7 0.7 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP10737.1 - 2.2e-08 34.0 4.1 0.00078 19.4 0.9 2.7 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEP10737.1 - 7.2e-05 23.0 0.7 0.6 10.5 0.1 2.7 2 1 1 3 3 3 3 EF-hand domain TerB PF05099.13 CEP10737.1 - 0.00015 21.8 0.4 0.41 10.6 0.0 2.7 2 1 1 3 3 3 2 Tellurite resistance protein TerB p25-alpha PF05517.12 CEP10737.1 - 0.00016 21.9 7.6 0.0014 18.8 0.8 3.0 2 1 2 4 4 4 2 p25-alpha EF-hand_14 PF17959.1 CEP10737.1 - 0.0016 18.7 1.0 1.4 9.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 CEP10737.1 - 0.032 14.2 1.9 0.57 10.1 1.2 2.7 1 1 0 1 1 1 0 Caleosin related protein Dockerin_1 PF00404.18 CEP10737.1 - 0.068 13.4 11.9 2 8.7 4.8 3.0 2 1 0 2 2 2 0 Dockerin type I domain Peptidase_S46 PF10459.9 CEP10737.1 - 0.074 11.7 3.4 0.58 8.7 0.3 2.0 1 1 1 2 2 2 0 Peptidase S46 UPF0154 PF03672.13 CEP10737.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RVT_1 PF00078.27 CEP10739.1 - 9.5e-13 48.2 0.1 1.5e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_fiss_reg PF05308.11 CEP10740.1 - 4.9 7.2 12.1 0.83 9.7 4.6 2.5 2 1 1 3 3 3 0 Mitochondrial fission regulator Med25_SD1 PF11235.8 CEP10741.1 - 0.15 12.4 0.7 4.1 7.7 0.2 2.0 1 1 1 2 2 2 0 Mediator complex subunit 25 synapsin 1 Perilipin PF03036.16 CEP10742.1 - 3.2e-14 52.8 12.6 3.2e-11 42.9 0.5 2.1 1 1 1 2 2 2 2 Perilipin family DUF848 PF05852.11 CEP10742.1 - 0.066 13.3 4.1 0.13 12.4 0.6 2.8 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Phasin PF05597.11 CEP10742.1 - 0.26 11.3 2.7 6.8 6.7 0.0 3.3 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) KH_dom-like PF14714.6 CEP10742.1 - 0.37 11.1 2.5 8.8 6.7 0.0 3.0 3 0 0 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Apolipoprotein PF01442.18 CEP10742.1 - 1.2 8.9 7.3 2.3 8.1 4.4 2.7 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3767 PF12597.8 CEP10743.1 - 3.1e-30 104.0 0.0 3.9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) ATP-synt PF00231.19 CEP10744.1 - 1.7e-75 254.4 4.6 1.9e-75 254.2 4.6 1.0 1 0 0 1 1 1 1 ATP synthase AHD PF17793.1 CEP10744.1 - 0.45 10.3 2.6 1.2 8.9 1.3 2.3 2 0 0 2 2 2 0 ANC1 homology domain (AHD) zf-C2H2 PF00096.26 CEP10745.1 - 9.7e-09 35.2 28.0 0.00015 22.0 0.6 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP10745.1 - 2.1e-07 31.1 10.8 4.5e-06 26.8 1.9 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP10745.1 - 1.3e-06 28.7 22.3 0.0044 17.7 0.5 5.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP10745.1 - 0.024 14.7 0.2 0.024 14.7 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP10745.1 - 0.18 12.4 0.0 0.18 12.4 0.0 5.0 2 1 3 5 5 5 0 FOXP coiled-coil domain MATH PF00917.26 CEP10745.1 - 0.31 11.2 4.6 0.11 12.6 0.8 2.2 2 0 0 2 2 2 0 MATH domain zf-TRAF PF02176.18 CEP10745.1 - 1.4 9.7 11.6 0.86 10.3 2.2 3.0 2 1 1 3 3 3 0 TRAF-type zinc finger Zap1_zf2 PF18217.1 CEP10745.1 - 2.5 8.2 8.4 0.33 11.0 0.9 3.1 3 0 0 3 3 3 0 Zap1 zinc finger 2 Aminotran_5 PF00266.19 CEP10746.1 - 9.5e-95 317.7 0.0 1.1e-94 317.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEP10746.1 - 1.8e-08 34.0 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEP10746.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CEP10746.1 - 0.00046 19.0 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CEP10746.1 - 0.0046 15.5 0.0 0.0075 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Tctex-1 PF03645.13 CEP10746.1 - 0.023 14.9 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 Tctex-1 family 4_1_CTD PF05902.13 CEP10746.1 - 0.053 13.6 0.3 0.12 12.5 0.3 1.6 1 1 0 1 1 1 0 4.1 protein C-terminal domain (CTD) CsbD PF05532.12 CEP10747.1 - 2.2e-17 62.7 19.3 1.1e-10 41.3 4.4 2.0 1 1 1 2 2 2 2 CsbD-like Mrr_cat PF04471.12 CEP10747.1 - 0.038 14.0 1.7 0.041 13.9 0.4 1.6 1 1 1 2 2 2 0 Restriction endonuclease Endonuclease_5 PF04493.14 CEP10748.1 - 1.3e-68 230.6 0.0 1.5e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 CEP10748.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 NCA2 PF08637.10 CEP10749.1 - 6.5e-87 291.4 3.3 1.4e-86 290.3 3.3 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 HetR_C PF18460.1 CEP10749.1 - 0.1 12.5 0.3 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Ion_trans PF00520.31 CEP10750.1 - 5.2e-96 320.6 78.0 6.9e-27 94.2 10.0 5.7 5 1 1 6 6 6 5 Ion transport protein GPHH PF16905.5 CEP10750.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Renin_r PF07850.14 CEP10750.1 - 4.9 7.8 12.3 0.03 14.9 1.0 3.4 3 0 0 3 3 3 0 Renin receptor-like protein Q_salvage PF10343.9 CEP10752.1 - 2.5e-30 106.0 0.0 1.7e-28 100.0 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family E1-E2_ATPase PF00122.20 CEP10753.1 - 2.8e-46 157.3 2.8 2.8e-46 157.3 2.8 3.5 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 CEP10753.1 - 6.4e-21 75.6 0.1 1.4e-20 74.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP10753.1 - 1.6e-12 47.0 0.0 3.9e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP10753.1 - 0.032 14.0 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Chitin_synth_2 PF03142.15 CEP10754.1 - 3.5e-278 923.5 0.1 4.8e-278 923.0 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP10754.1 - 1.4e-13 51.2 1.8 3.7e-13 49.8 1.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP10754.1 - 4.4e-13 49.7 0.0 2.8e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEP10754.1 - 0.0045 16.5 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEP10754.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Epimerase PF01370.21 CEP10755.1 - 3.8e-24 85.5 0.0 4.9e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP10755.1 - 1.7e-11 43.7 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CEP10755.1 - 8.8e-11 41.8 0.0 1.7e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CEP10755.1 - 1.4e-09 37.5 0.0 2.6e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEP10755.1 - 1.9e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CEP10755.1 - 0.0014 18.8 0.1 0.013 15.8 0.0 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CEP10755.1 - 0.0033 16.6 0.4 0.54 9.4 0.1 2.9 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 CEP10755.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tube PF17212.3 CEP10755.1 - 0.042 13.9 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Tail tubular protein RhoGEF PF00621.20 CEP10757.1 - 2e-27 96.6 1.4 5.4e-27 95.2 1.4 1.8 1 0 0 1 1 1 1 RhoGEF domain DUF4689 PF15755.5 CEP10757.1 - 0.26 10.9 2.9 0.45 10.1 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) GHMP_kinases_N PF00288.26 CEP10758.1 - 5e-14 52.3 1.0 1.4e-13 50.8 1.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEP10758.1 - 8.8e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal tRNA_anti_2 PF13742.6 CEP10758.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PHD PF00628.29 CEP10759.1 - 1.5e-07 31.1 14.6 2.6e-07 30.4 14.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP10759.1 - 0.0018 17.7 8.6 0.0029 17.1 8.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CEP10759.1 - 0.029 14.4 6.1 0.054 13.5 6.1 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger NIPSNAP PF07978.13 CEP10760.1 - 4.7e-33 113.5 0.2 4.1e-24 84.8 0.1 2.6 2 1 0 2 2 2 2 NIPSNAP CBFD_NFYB_HMF PF00808.23 CEP10761.1 - 4e-18 65.5 0.4 7.3e-18 64.6 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP10761.1 - 4.3e-06 27.1 0.2 4.3e-06 27.1 0.2 2.6 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 FSA_C PF10479.9 CEP10761.1 - 0.53 8.4 7.3 0.6 8.2 7.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus EamA PF00892.20 CEP10762.1 - 9.6e-05 22.6 8.0 9.6e-05 22.6 8.0 2.2 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 CEP10762.1 - 0.0057 16.0 14.5 0.01 15.2 14.5 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family PHO4 PF01384.20 CEP10762.1 - 1.2 8.1 15.9 0.014 14.4 2.6 2.3 2 1 0 2 2 2 0 Phosphate transporter family ArAE_2 PF10334.9 CEP10763.1 - 7.9e-21 74.9 0.1 1.4e-20 74.1 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 CEP10763.1 - 1e-16 61.2 14.2 1e-16 61.2 14.2 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 CEP10763.1 - 8.4e-14 51.5 3.6 8.4e-14 51.5 3.6 3.0 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 CEP10763.1 - 1.3e-06 27.3 6.1 1.3e-06 27.3 6.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein family SOG2 PF10428.9 CEP10763.1 - 0.00012 21.4 6.4 0.00024 20.5 1.5 2.1 2 0 0 2 2 2 1 RAM signalling pathway protein ALMT PF11744.8 CEP10763.1 - 0.49 9.2 14.3 0.098 11.5 6.5 2.7 2 1 0 2 2 2 0 Aluminium activated malate transporter DUF3149 PF11346.8 CEP10763.1 - 2.3 7.9 11.0 0.7 9.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Asp PF00026.23 CEP10764.1 - 5.1e-61 206.8 0.0 2.8e-60 204.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP10764.1 - 3.1e-13 50.4 4.9 8.6e-07 29.4 0.1 3.8 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEP10764.1 - 0.0034 18.0 0.7 0.042 14.5 0.1 2.9 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 CEP10764.1 - 0.016 15.0 0.1 0.16 11.7 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 CEP10765.1 - 1.7e-73 247.8 0.3 2.4e-72 244.1 0.3 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP10765.1 - 9.2e-14 52.1 3.2 2.2e-08 34.6 0.0 4.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP10765.1 - 0.0057 16.4 0.3 0.07 12.9 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal LIP1 PF15904.5 CEP10765.1 - 0.03 14.7 0.0 0.097 13.0 0.0 1.8 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Asp_protease_2 PF13650.6 CEP10765.1 - 0.076 13.7 0.2 9.5 6.9 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Asp PF00026.23 CEP10766.1 - 1.3e-72 244.9 1.2 1.7e-72 244.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP10766.1 - 9.1e-14 52.1 2.7 9.8e-10 38.9 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP10766.1 - 0.033 13.9 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP10766.1 - 0.086 13.5 0.5 6.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Aspartyl protease F-box-like PF12937.7 CEP10769.1 - 0.022 14.6 0.4 0.12 12.3 0.1 2.4 2 0 0 2 2 2 0 F-box-like CBM49 PF09478.10 CEP10769.1 - 0.32 11.3 4.5 3.5 8.0 0.8 3.0 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 UTP25 PF06862.12 CEP10770.1 - 6.1e-195 648.5 8.2 8.5e-195 648.0 8.2 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UPF0052 PF01933.18 CEP10771.1 - 6.5e-51 173.3 0.0 1e-50 172.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 UPF0524 PF15823.5 CEP10771.1 - 0.014 14.8 1.3 3 7.2 0.3 2.4 2 0 0 2 2 2 0 UPF0524 of C3orf70 Ycf70 PF17382.2 CEP10772.1 - 0.16 12.4 0.4 4.1 7.9 0.0 3.0 2 0 0 2 2 2 0 Uncharacterized Ycf70-like SurA_N_2 PF13623.6 CEP10772.1 - 4.8 7.0 6.5 0.25 11.2 0.8 1.8 2 0 0 2 2 2 0 SurA N-terminal domain ABC_tran PF00005.27 CEP10773.1 - 3.7e-46 157.0 0.9 1.9e-22 80.3 0.0 3.3 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CEP10773.1 - 9.5e-24 83.2 5.1 9.5e-24 83.2 5.1 2.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 CEP10773.1 - 1.4e-11 44.3 4.7 0.0014 18.1 0.0 4.4 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEP10773.1 - 1e-10 41.9 12.6 0.026 14.3 0.1 5.1 3 2 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEP10773.1 - 2.4e-07 31.3 1.4 0.036 14.4 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CEP10773.1 - 3.4e-07 30.6 0.4 0.026 14.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEP10773.1 - 4.2e-07 30.6 0.0 0.032 14.8 0.0 4.5 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.6 CEP10773.1 - 7.6e-07 28.8 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEP10773.1 - 1.1e-06 28.7 0.0 0.071 13.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CEP10773.1 - 2.7e-06 27.7 0.5 0.078 13.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CEP10773.1 - 8e-06 25.8 0.0 0.042 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CEP10773.1 - 4.5e-05 24.1 25.6 0.11 13.0 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 CEP10773.1 - 0.00016 21.4 0.0 0.76 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 CEP10773.1 - 0.00061 19.6 0.1 0.044 13.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP10773.1 - 0.00069 19.8 2.5 0.54 10.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 CEP10773.1 - 0.0016 18.4 0.0 1.7 8.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_27 PF13514.6 CEP10773.1 - 0.0025 17.5 3.7 0.26 10.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CEP10773.1 - 0.0038 17.6 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 CEP10773.1 - 0.005 17.3 0.1 6.5 7.2 0.1 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CEP10773.1 - 0.0055 16.5 24.1 0.17 11.6 0.0 4.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.6 CEP10773.1 - 0.0077 16.3 3.5 2.2 8.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain MeaB PF03308.16 CEP10773.1 - 0.021 13.8 0.0 4.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CEP10773.1 - 0.024 14.9 0.0 7.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CEP10773.1 - 0.027 13.7 0.0 9.4 5.4 0.0 2.6 2 0 0 2 2 2 0 Septin dNK PF01712.19 CEP10773.1 - 0.041 13.7 1.2 2.2 8.1 0.0 3.3 3 0 0 3 3 3 0 Deoxynucleoside kinase Ploopntkinase1 PF18748.1 CEP10773.1 - 0.045 13.3 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase1 Dynamin_N PF00350.23 CEP10773.1 - 0.045 13.8 11.7 0.37 10.8 0.0 4.0 4 1 0 4 4 4 0 Dynamin family Arf PF00025.21 CEP10773.1 - 0.047 13.1 0.2 1.1 8.6 0.0 3.1 4 0 0 4 4 4 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CEP10773.1 - 0.06 13.1 1.5 3.8 7.2 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 CEP10773.1 - 0.069 12.7 0.1 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 CEP10773.1 - 0.088 13.1 0.9 1.6 9.0 0.2 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 CEP10773.1 - 0.11 12.4 0.1 8.9 6.2 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 CEP10773.1 - 0.12 11.8 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 CEP10773.1 - 0.16 12.0 0.0 0.16 12.0 0.0 4.8 4 1 1 5 5 5 0 Helicase HerA, central domain UPF0184 PF03670.13 CEP10773.1 - 0.18 12.2 4.3 1.8 9.0 0.9 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF5320 PF17253.2 CEP10773.1 - 4.9 8.3 5.4 9.3 7.4 0.8 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Paf67 PF10255.9 CEP10774.1 - 2.8e-169 563.4 8.0 3.7e-169 563.0 8.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 CEP10774.1 - 0.0018 18.2 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP10774.1 - 0.067 13.0 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP10774.1 - 0.073 13.4 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 CEP10775.1 - 8.3e-74 249.0 0.0 3e-73 247.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 zf-RING_2 PF13639.6 CEP10775.1 - 1.5e-05 25.3 8.8 4e-05 23.9 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP10775.1 - 5.4e-05 23.1 7.1 0.00017 21.6 7.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SPATA1_C PF15743.5 CEP10775.1 - 0.035 14.2 0.1 0.081 13.0 0.1 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus WD40 PF00400.32 CEP10775.1 - 0.14 13.1 0.1 0.63 11.0 0.1 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-rbx1 PF12678.7 CEP10775.1 - 0.18 12.1 7.6 0.63 10.4 7.6 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEP10775.1 - 0.21 11.5 11.4 0.48 10.3 11.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 CEP10775.1 - 0.53 10.8 4.7 1.7 9.2 2.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB zf-RING_11 PF17123.5 CEP10775.1 - 0.59 9.9 7.2 1.8 8.4 7.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CEP10775.1 - 0.75 10.0 6.0 2.9 8.1 6.0 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Questin_oxidase PF14027.6 CEP10776.1 - 9.7e-94 314.7 0.1 1.3e-93 314.2 0.1 1.2 1 0 0 1 1 1 1 Questin oxidase-like DUF1910 PF08928.10 CEP10776.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) PRD PF00874.20 CEP10776.1 - 0.4 11.0 2.1 30 5.0 0.6 2.5 2 0 0 2 2 2 0 PRD domain BCDHK_Adom3 PF10436.9 CEP10777.1 - 1.1e-41 142.3 0.0 2.3e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEP10777.1 - 9e-14 51.9 0.0 2.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IATP PF04568.12 CEP10777.1 - 0.00027 21.3 0.7 0.00082 19.8 0.7 1.9 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HATPase_c_3 PF13589.6 CEP10777.1 - 0.028 14.2 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 CEP10777.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 GHKL domain Sec2p PF06428.11 CEP10777.1 - 0.26 11.3 6.6 0.27 11.2 4.8 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2076 PF09849.9 CEP10777.1 - 0.26 11.3 30.3 0.026 14.6 19.9 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-BED PF02892.15 CEP10778.1 - 3.7e-06 26.9 0.4 7.1e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 BED zinc finger UPF0547 PF10571.9 CEP10778.1 - 0.31 11.2 1.7 16 5.7 0.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 p450 PF00067.22 CEP10779.1 - 2.2e-54 185.0 0.0 2.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEPN_MAE_28990 PF18737.1 CEP10780.1 - 0.0051 16.8 0.7 0.009 16.0 0.7 1.4 1 0 0 1 1 1 1 MAE_28990/MAE_18760-like HEPN Pam17 PF08566.10 CEP10780.1 - 0.93 9.3 5.9 0.3 10.9 2.4 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Pkinase PF00069.25 CEP10781.1 - 1.8e-21 76.7 0.0 3.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10781.1 - 2.9e-17 62.8 0.1 9.4e-17 61.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Rad60-SLD PF11976.8 CEP10782.1 - 1.6e-20 72.7 2.1 9.7e-17 60.6 0.9 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEP10782.1 - 0.00045 19.9 0.5 0.00099 18.8 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family hNIFK_binding PF12196.8 CEP10782.1 - 0.033 13.7 0.2 0.033 13.7 0.2 2.4 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ThiS PF02597.20 CEP10782.1 - 0.16 12.6 0.2 0.43 11.2 0.2 1.7 1 0 0 1 1 1 0 ThiS family PBP PF01161.20 CEP10783.1 - 8.3e-13 48.8 0.2 1.9e-12 47.6 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein zf-RVT PF13966.6 CEP10784.1 - 0.0049 17.6 1.8 0.008 16.9 1.1 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Integrase_H2C2 PF17921.1 CEP10785.1 - 2.8e-12 46.5 0.4 6e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP10785.1 - 3.2e-12 46.7 0.0 6.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP10785.1 - 3e-11 43.1 2.2 1.6e-10 40.7 0.6 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP10785.1 - 0.00026 21.1 0.3 0.00062 19.9 0.3 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Tudor-knot PF11717.8 CEP10785.1 - 0.078 12.9 1.8 0.35 10.8 0.1 2.7 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain NPV_P10 PF05531.12 CEP10785.1 - 0.097 13.2 2.5 2.5 8.6 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Anillin_N PF16018.5 CEP10785.1 - 0.65 10.6 3.3 0.57 10.8 0.5 2.2 2 0 0 2 2 2 0 Anillin N-terminus STI1 PF17830.1 CEP10786.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 STI1 domain DUF3408 PF11888.8 CEP10787.1 - 0.13 12.4 10.5 0.57 10.3 6.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3408) DUF2052 PF09747.9 CEP10787.1 - 1.1 9.4 14.2 1.8 8.6 13.6 1.7 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Glyco_hydro_18 PF00704.28 CEP10788.1 - 1.3e-69 235.4 2.4 1.5e-69 235.2 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 CEP10788.1 - 0.078 12.2 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 ubiquitin PF00240.23 CEP10789.1 - 5.5e-34 115.8 1.0 7.2e-34 115.4 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CEP10789.1 - 6.5e-31 106.0 12.1 1.1e-30 105.2 12.1 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CEP10789.1 - 2.8e-16 59.1 0.8 4.5e-16 58.4 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEP10789.1 - 3.3e-05 24.3 0.2 0.00013 22.3 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CEP10789.1 - 0.0055 17.0 0.1 0.0091 16.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEP10789.1 - 0.01 15.7 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP10789.1 - 0.021 14.9 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CEP10789.1 - 0.031 14.3 1.2 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CEP10789.1 - 0.036 14.6 0.1 0.046 14.3 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Clathrin PF00637.20 CEP10790.1 - 5.1e-25 88.0 0.7 5.1e-25 88.0 0.7 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CEP10790.1 - 0.00044 20.7 0.8 0.0019 18.6 0.1 2.4 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 CEP10790.1 - 0.00071 20.3 0.1 0.0031 18.3 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat WD40_like PF17005.5 CEP10790.1 - 0.0017 17.7 0.7 0.19 11.0 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain zf-RING_5 PF14634.6 CEP10790.1 - 0.0051 16.7 2.7 0.014 15.3 2.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain CENP-B_dimeris PF09026.10 CEP10790.1 - 0.023 15.0 5.3 0.082 13.3 5.3 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.6 CEP10790.1 - 0.042 14.2 6.7 0.35 11.2 6.7 2.4 1 1 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 CEP10790.1 - 0.37 10.6 2.9 0.89 9.4 2.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 CEP10790.1 - 0.82 9.7 5.3 0.13 12.3 0.8 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 CEP10790.1 - 1.1 9.6 7.0 1.2 9.5 2.7 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Polysacc_synt_4 PF04669.13 CEP10791.1 - 4.6e-19 68.7 2.8 3.7e-17 62.5 2.8 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DAO PF01266.24 CEP10792.1 - 1.6e-52 179.3 0.1 2.1e-52 178.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP10792.1 - 5e-06 26.0 1.0 0.0016 17.7 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP10792.1 - 2.9e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CEP10792.1 - 0.00016 21.8 0.1 0.00037 20.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 CEP10792.1 - 0.0019 16.8 0.0 0.023 13.3 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 CEP10792.1 - 0.0021 17.4 0.1 0.1 11.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 CEP10792.1 - 0.014 15.6 0.3 0.083 13.1 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 CEP10792.1 - 0.029 13.5 0.3 0.041 13.0 0.3 1.5 1 1 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CEP10792.1 - 0.051 12.6 0.1 0.092 11.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CEP10792.1 - 0.078 13.0 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CEP10792.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 CEP10792.1 - 0.11 12.7 0.5 0.23 11.7 0.2 1.7 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 CEP10792.1 - 0.12 11.6 0.1 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CEP10792.1 - 0.18 12.3 0.2 0.56 10.7 0.2 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding DDE_3 PF13358.6 CEP10793.1 - 2.3e-28 98.8 0.0 3.8e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 CEP10793.1 - 3.1e-06 27.1 0.0 8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_29 PF13551.6 CEP10793.1 - 0.00026 21.0 0.1 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 CEP10793.1 - 0.0011 19.6 0.0 0.0093 16.6 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CEP10793.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF4322 PF14210.6 CEP10793.1 - 0.022 14.6 0.1 0.07 13.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) HTH_Tnp_ISL3 PF13542.6 CEP10793.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Ras PF00071.22 CEP10794.1 - 8e-37 126.3 0.0 8.8e-37 126.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP10794.1 - 1.5e-12 47.8 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP10794.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP10794.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Tli4_N PF18443.1 CEP10795.1 - 0.26 11.6 3.2 0.67 10.3 3.2 1.7 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Velvet PF11754.8 CEP10796.1 - 1e-37 130.5 7.0 2.6e-31 109.4 0.2 2.9 2 1 1 3 3 3 2 Velvet factor CAP_N PF01213.19 CEP10797.1 - 0.0064 16.0 6.4 0.0064 16.0 6.4 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CEP10797.1 - 0.18 11.9 14.1 0.059 13.4 7.7 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PL48 PF15903.5 CEP10797.1 - 6.9 5.5 9.1 0.064 12.2 0.7 1.8 2 0 0 2 2 2 0 Filopodia upregulated, FAM65 LRR_8 PF13855.6 CEP10799.1 - 1.5e-15 56.7 29.6 3.6e-08 33.1 11.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEP10799.1 - 2.1e-14 53.4 21.6 5.5e-07 29.8 1.3 3.4 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEP10799.1 - 3.3e-05 23.5 7.5 0.033 13.7 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CEP10799.1 - 0.027 15.0 21.0 4.5 8.2 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat Zds_C PF08632.10 CEP10800.1 - 2e-26 91.5 0.9 2e-26 91.5 0.9 2.4 3 0 0 3 3 3 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term O-FucT PF10250.9 CEP10801.1 - 7.1e-17 62.1 0.5 2.8e-14 53.6 0.5 3.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AAA PF00004.29 CEP10802.1 - 2.6e-79 264.1 0.1 1.1e-45 155.3 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP10802.1 - 3.7e-28 97.1 5.4 1.7e-14 53.4 1.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CEP10802.1 - 4.5e-14 52.5 0.0 8e-07 28.9 0.0 3.5 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEP10802.1 - 6e-12 46.3 1.1 6.1e-07 30.0 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CEP10802.1 - 1.3e-11 45.0 0.4 5.4e-05 23.5 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CEP10802.1 - 5.5e-10 39.4 0.5 2.7e-05 24.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CEP10802.1 - 2.5e-09 36.8 0.9 0.00011 21.5 0.0 3.1 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 CEP10802.1 - 1.2e-08 35.2 0.1 0.00019 21.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.14 CEP10802.1 - 3.4e-08 33.8 0.7 1.1e-05 25.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEP10802.1 - 5.5e-07 29.5 0.0 0.007 16.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 CEP10802.1 - 1.7e-06 28.4 0.0 0.23 11.8 0.0 3.5 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 CEP10802.1 - 2e-06 27.3 0.4 0.081 12.3 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CEP10802.1 - 6.9e-06 26.1 0.1 0.034 14.0 0.0 3.3 2 1 1 3 3 3 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 CEP10802.1 - 1.6e-05 25.1 0.0 0.008 16.3 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CEP10802.1 - 3.4e-05 23.4 0.0 0.066 12.7 0.0 3.1 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CEP10802.1 - 3.6e-05 24.3 0.0 0.034 14.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEP10802.1 - 4e-05 23.9 0.1 0.044 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEP10802.1 - 9e-05 22.1 0.1 3.1 7.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CEP10802.1 - 9.8e-05 22.4 0.0 0.00062 19.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CEP10802.1 - 0.00034 20.0 2.3 0.37 10.1 0.1 3.7 3 1 1 4 4 4 2 KaiC TsaE PF02367.17 CEP10802.1 - 0.00045 20.2 0.0 0.48 10.4 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CEP10802.1 - 0.00046 19.9 0.2 0.19 11.4 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_3 PF07726.11 CEP10802.1 - 0.00065 19.6 0.0 2 8.3 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CEP10802.1 - 0.0011 19.5 2.2 0.31 11.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.12 CEP10802.1 - 0.0018 17.6 0.1 0.47 9.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF2722 PF10846.8 CEP10802.1 - 0.0028 16.7 0.6 0.0038 16.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF815 PF05673.13 CEP10802.1 - 0.0033 16.6 0.0 0.084 12.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Vps4_C PF09336.10 CEP10802.1 - 0.0041 17.1 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 CEP10802.1 - 0.0071 16.8 0.0 2.2 8.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CEP10802.1 - 0.0081 16.1 0.8 8.7 6.2 0.0 3.6 4 0 0 4 4 3 0 NACHT domain AAA_24 PF13479.6 CEP10802.1 - 0.0084 15.9 2.3 0.29 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 CEP10802.1 - 0.0086 15.2 0.0 0.56 9.2 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 CDC48_N PF02359.18 CEP10802.1 - 0.0087 16.2 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain PhoH PF02562.16 CEP10802.1 - 0.0091 15.5 0.3 0.47 9.9 0.1 2.5 2 0 0 2 2 2 1 PhoH-like protein IPT PF01745.16 CEP10802.1 - 0.082 12.3 4.3 0.32 10.4 0.1 3.0 3 0 0 3 3 3 0 Isopentenyl transferase AAA_19 PF13245.6 CEP10802.1 - 0.3 11.4 2.8 2.3 8.5 0.2 3.4 3 1 1 4 4 2 0 AAA domain zf-C2H2 PF00096.26 CEP10803.1 - 0.16 12.5 0.7 0.16 12.5 0.7 3.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type LIM PF00412.22 CEP10803.1 - 0.19 12.0 2.4 11 6.3 0.1 2.5 2 0 0 2 2 2 0 LIM domain zf-C2H2_jaz PF12171.8 CEP10803.1 - 2.8 8.3 8.5 0.51 10.7 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CdhC PF03598.15 CEP10805.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Retrotrans_gag PF03732.17 CEP10806.1 - 4.5e-08 33.2 0.5 2.5e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP10806.1 - 1.5e-06 28.0 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CEP10806.1 - 0.092 12.9 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 CEP10807.1 - 1.7e-17 63.6 0.0 2.3e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease NDC10_II PF16787.5 CEP10808.1 - 1.7e-05 24.0 2.9 3.4e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Perilipin PF03036.16 CEP10808.1 - 0.00055 19.1 1.8 0.00078 18.6 1.8 1.1 1 0 0 1 1 1 1 Perilipin family SWC7 PF17330.2 CEP10808.1 - 0.0011 19.0 0.4 0.0024 17.9 0.2 1.6 1 1 1 2 2 2 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 GAT PF03127.14 CEP10808.1 - 0.039 14.3 1.8 0.06 13.7 1.8 1.4 1 0 0 1 1 1 0 GAT domain UvrD_C_2 PF13538.6 CEP10810.1 - 0.00019 21.2 0.8 0.058 13.2 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Mit_KHE1 PF10173.9 CEP10811.1 - 0.064 13.3 1.6 0.62 10.1 1.6 2.0 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related FAM76 PF16046.5 CEP10811.1 - 0.14 11.5 1.0 0.22 10.8 1.0 1.3 1 0 0 1 1 1 0 FAM76 protein HDV_ag PF01517.18 CEP10813.1 - 1.8 8.3 4.6 12 5.6 0.5 2.1 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen MORN PF02493.20 CEP10813.1 - 2.3 8.3 12.2 3.4 7.8 0.2 4.1 4 0 0 4 4 4 0 MORN repeat Senescence PF06911.12 CEP10814.1 - 2.2e-32 112.8 4.7 5.4e-32 111.6 4.7 1.7 1 0 0 1 1 1 1 Senescence-associated protein zinc_ribbon_16 PF17034.5 CEP10814.1 - 1.7e-09 38.0 8.8 1.1e-07 32.1 8.9 2.9 1 1 1 2 2 2 1 Zinc-ribbon like family TPPII PF12580.8 CEP10814.1 - 0.048 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II Zn_ribbon_17 PF17120.5 CEP10814.1 - 1.8 8.3 4.9 4.9 6.9 4.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TFIIA PF03153.13 CEP10814.1 - 4.4 7.2 22.0 0.2 11.6 5.9 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Zw10 PF06248.13 CEP10815.1 - 2.6e-38 131.9 0.8 1e-33 116.8 0.5 2.2 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 CEP10815.1 - 8.8e-09 35.4 0.1 8.8e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Sec8_exocyst PF04048.14 CEP10815.1 - 2.7e-05 24.1 11.1 0.0019 18.1 9.2 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Prominin PF05478.11 CEP10815.1 - 0.0021 16.1 2.9 1.4 6.8 0.0 2.3 2 0 0 2 2 2 2 Prominin COG2 PF06148.11 CEP10815.1 - 0.01 15.9 5.4 0.029 14.5 5.4 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 CEP10815.1 - 0.029 15.1 1.0 1.4 9.7 1.5 2.9 2 0 0 2 2 2 0 Occludin homology domain GAT PF03127.14 CEP10815.1 - 0.067 13.5 4.4 1.8 8.9 2.6 3.9 3 1 0 3 3 3 0 GAT domain Mlf1IP PF10248.9 CEP10815.1 - 0.079 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Dor1 PF04124.12 CEP10815.1 - 0.15 10.8 6.1 0.27 9.9 6.1 1.4 1 0 0 1 1 1 0 Dor1-like family ERAP1_C PF11838.8 CEP10815.1 - 0.16 11.5 2.8 1.1 8.8 0.4 2.7 2 1 0 2 2 2 0 ERAP1-like C-terminal domain THOC7 PF05615.13 CEP10815.1 - 0.17 12.2 4.2 0.35 11.1 4.2 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 Vps39_1 PF10366.9 CEP10815.1 - 0.24 11.7 1.4 0.7 10.2 1.4 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Muted PF14942.6 CEP10815.1 - 1 9.7 6.1 3.1 8.1 6.1 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF948 PF06103.11 CEP10815.1 - 2.1 8.7 4.6 8.4 6.7 3.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ParB PF08775.10 CEP10815.1 - 3.2 8.3 5.5 3.3 8.2 2.9 2.4 2 0 0 2 2 2 0 ParB family AreA_N PF07573.11 CEP10816.1 - 0.11 13.2 1.0 0.18 12.5 0.7 1.6 1 1 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus Uds1 PF15456.6 CEP10817.1 - 1.6e-20 73.6 11.3 1.6e-20 73.6 11.3 4.5 5 1 0 5 5 5 1 Up-regulated During Septation Rhodanese PF00581.20 CEP10817.1 - 3.6e-07 30.7 0.0 1.4e-06 28.8 0.0 2.1 1 0 0 1 1 1 1 Rhodanese-like domain Lsr2 PF11774.8 CEP10818.1 - 0.016 15.3 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Lsr2 Pestivirus_E2 PF16329.5 CEP10820.1 - 0.031 13.1 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 Pox_Ag35 PF03286.14 CEP10821.1 - 0.0084 15.9 5.3 0.0084 15.9 5.3 1.6 2 0 0 2 2 2 1 Pox virus Ag35 surface protein MMtag PF10159.9 CEP10821.1 - 0.019 15.3 4.4 0.04 14.2 4.4 1.5 1 0 0 1 1 1 0 Multiple myeloma tumor-associated XRCC4 PF06632.12 CEP10821.1 - 0.058 12.2 7.5 0.087 11.7 7.5 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 zf-Dof PF02701.15 CEP10821.1 - 0.18 12.0 2.8 0.22 11.7 0.5 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger Zn-ribbon_8 PF09723.10 CEP10821.1 - 0.19 11.8 2.5 45 4.3 0.0 3.6 4 0 0 4 4 4 0 Zinc ribbon domain PHD PF00628.29 CEP10821.1 - 1.9 8.4 9.9 6.9 6.7 2.5 3.0 2 2 0 2 2 2 0 PHD-finger DUF3088 PF11287.8 CEP10821.1 - 2.2 8.1 4.2 14 5.5 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3088) Tim54 PF11711.8 CEP10821.1 - 2.2 7.0 7.6 3.1 6.5 7.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 C1_4 PF07975.12 CEP10821.1 - 2.7 8.3 10.5 2.1 8.6 0.6 3.6 2 1 1 3 3 3 0 TFIIH C1-like domain Tom22 PF04281.13 CEP10821.1 - 2.9 7.7 9.8 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 FAM176 PF14851.6 CEP10821.1 - 3.4 7.3 6.1 1.5 8.5 3.3 1.7 2 0 0 2 2 2 0 FAM176 family Zn_Tnp_IS1595 PF12760.7 CEP10821.1 - 4 7.5 8.9 10 6.2 0.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain YABBY PF04690.13 CEP10821.1 - 4.3 7.9 16.7 0.81 10.2 0.4 3.1 3 0 0 3 3 3 0 YABBY protein Exo_endo_phos_2 PF14529.6 CEP10822.1 - 0.018 14.8 2.8 0.021 14.7 0.3 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase DUF3450 PF11932.8 CEP10823.1 - 0.054 12.8 0.9 0.064 12.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COPI_assoc PF08507.10 CEP10824.1 - 0.014 15.4 0.1 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 COPI associated protein ABC_membrane_2 PF06472.15 CEP10826.1 - 1.2e-92 310.1 2.7 1.7e-92 309.7 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEP10826.1 - 7.2e-19 68.7 0.0 2.7e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CEP10826.1 - 0.00015 21.7 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEP10826.1 - 0.00085 19.9 1.0 0.0055 17.2 1.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 CEP10826.1 - 0.0017 17.8 0.1 0.12 11.8 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbmA_BacA PF05992.12 CEP10826.1 - 0.011 15.2 0.8 0.019 14.4 0.8 1.3 1 0 0 1 1 1 0 SbmA/BacA-like family Adeno_IVa2 PF02456.15 CEP10826.1 - 0.039 12.8 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 CEP10826.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 CEP10826.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4042 PF13251.6 CEP10827.1 - 7.1e-35 120.4 4.0 2.1e-33 115.6 0.8 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 CEP10827.1 - 1.4e-12 47.8 10.3 0.0073 16.8 1.9 8.0 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 CEP10827.1 - 9.1e-12 45.2 0.9 0.00011 22.5 0.2 6.4 6 2 1 7 7 7 2 HEAT repeats HEAT PF02985.22 CEP10827.1 - 2.8e-10 39.5 21.3 0.0066 16.6 0.2 8.9 10 0 0 10 10 10 4 HEAT repeat Xpo1 PF08389.12 CEP10827.1 - 0.012 15.7 5.9 23 5.0 0.1 4.8 4 0 0 4 4 4 0 Exportin 1-like protein DUF5063 PF16702.5 CEP10827.1 - 0.068 13.6 0.1 0.7 10.3 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5063) Telomere_reg-2 PF10193.9 CEP10827.1 - 0.097 13.1 1.8 2.5 8.6 0.0 3.5 4 0 0 4 4 4 0 Telomere length regulation protein ATP11 PF06644.11 CEP10828.1 - 7.5e-68 229.3 3.1 8.8e-68 229.0 3.1 1.1 1 0 0 1 1 1 1 ATP11 protein RHH_4 PF13467.6 CEP10828.1 - 0.028 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain Dimerisation2 PF16864.5 CEP10828.1 - 0.038 14.0 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain DUF4168 PF13767.6 CEP10828.1 - 0.96 10.7 5.7 3.7 8.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) 60KD_IMP PF02096.20 CEP10829.1 - 1.2e-28 100.0 2.6 1.2e-28 100.0 2.6 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein Peptidase_S49_N PF08496.10 CEP10829.1 - 0.27 11.3 2.5 0.34 11.0 0.5 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 CEP10829.1 - 2 8.1 16.7 1.4 8.7 0.6 3.3 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like HATPase_c PF02518.26 CEP10830.1 - 1.2e-30 106.3 0.1 2.9e-30 105.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP10830.1 - 1.3e-19 70.4 0.2 2.2e-18 66.5 0.0 3.3 4 0 0 4 4 4 1 Response regulator receiver domain AAA_16 PF13191.6 CEP10830.1 - 2.1e-17 64.0 0.1 2.4e-16 60.6 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 CEP10830.1 - 2.4e-17 62.7 0.2 2e-16 59.8 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 CEP10830.1 - 1.6e-15 57.2 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10830.1 - 3.3e-09 36.4 0.0 7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.6 CEP10830.1 - 0.00015 22.0 0.0 0.0019 18.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain GAF_2 PF13185.6 CEP10830.1 - 0.0016 18.8 0.0 0.0059 16.9 0.0 2.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CEP10830.1 - 0.002 18.7 0.0 0.0056 17.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain ATPase_2 PF01637.18 CEP10830.1 - 0.0028 17.6 0.6 0.026 14.4 0.6 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CEP10830.1 - 0.0064 15.7 0.2 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 CEP10830.1 - 0.0091 16.5 0.0 0.038 14.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 CEP10830.1 - 0.022 14.7 0.5 0.23 11.4 0.5 2.6 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CEP10830.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP10830.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 CEP10830.1 - 0.11 12.6 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CEP10830.1 - 0.12 12.4 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC1 PF03109.16 CEP10831.1 - 1.3e-31 109.2 0.1 2.8e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CEP10831.1 - 0.0002 21.4 0.0 0.0074 16.2 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 CEP10831.1 - 0.00064 19.4 0.2 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 CEP10831.1 - 0.08 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rho_RNA_bind PF07497.12 CEP10831.1 - 0.086 12.7 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain ADK PF00406.22 CEP10832.1 - 1.3e-12 48.1 0.3 9.7e-12 45.2 0.2 2.4 2 1 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 CEP10832.1 - 8.9e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP10832.1 - 0.082 13.5 0.3 0.46 11.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain A_deaminase PF00962.22 CEP10833.1 - 7.2e-38 130.7 0.6 2.8e-27 95.9 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase TyeA PF09059.10 CEP10833.1 - 0.048 13.8 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 TyeA Oxysterol_BP PF01237.18 CEP10835.1 - 4.7e-68 229.7 0.4 7.8e-58 196.1 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein BCNT PF07572.12 CEP10836.1 - 6.5e-22 77.4 3.4 6.5e-22 77.4 3.4 2.0 3 0 0 3 3 3 1 Bucentaur or craniofacial development YL1 PF05764.13 CEP10836.1 - 0.00012 22.3 21.6 0.00012 22.3 21.6 1.4 2 0 0 2 2 2 1 YL1 nuclear protein SDA1 PF05285.12 CEP10836.1 - 0.0054 16.2 27.9 0.0063 16.0 27.9 1.1 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.12 CEP10836.1 - 0.024 13.3 25.9 0.03 12.9 25.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.9 CEP10836.1 - 0.034 13.3 18.8 0.048 12.8 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 CEP10836.1 - 0.11 10.8 14.1 0.12 10.6 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Med3 PF11593.8 CEP10836.1 - 0.47 9.6 7.6 0.6 9.2 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_9 PF00759.19 CEP10837.1 - 2.6e-115 386.1 16.2 3e-115 385.9 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FAA_hydrolase PF01557.18 CEP10838.1 - 5e-52 176.7 0.0 6.8e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family tRNA-synt_His PF13393.6 CEP10840.1 - 1.2e-39 136.5 0.0 1.4e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CEP10840.1 - 1.2e-13 51.0 0.1 2.7e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CEP10840.1 - 2.9e-07 30.3 0.1 4.4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 CEP10840.1 - 6e-07 29.6 0.0 6.5e-06 26.2 0.0 2.5 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CEP10840.1 - 2.1e-05 23.7 0.2 0.0053 15.9 0.0 2.9 3 1 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CEP10840.1 - 0.0067 15.9 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) YdaS_antitoxin PF15943.5 CEP10840.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DEAD PF00270.29 CEP10842.1 - 1.3e-43 148.8 0.0 2.6e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CEP10842.1 - 3.5e-22 78.4 0.1 1.2e-21 76.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CEP10842.1 - 1.7e-20 73.4 0.0 8.2e-20 71.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP10842.1 - 1.3e-07 31.8 0.0 1.3e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP10842.1 - 0.0024 18.2 0.0 0.0092 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Spore_III_AB PF09548.10 CEP10842.1 - 8.5 6.5 11.7 21 5.2 11.7 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PAC3 PF10178.9 CEP10843.1 - 1e-20 73.7 0.0 1.3e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HSF_DNA-bind PF00447.17 CEP10844.1 - 8.5e-33 112.9 3.3 8.5e-33 112.9 3.3 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding DUF4226 PF10774.9 CEP10844.1 - 0.018 15.3 1.4 0.03 14.6 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) MINDY_DUB PF04424.13 CEP10845.1 - 4.2e-36 123.5 0.0 7.9e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase zf-CCCH PF00642.24 CEP10846.1 - 3.4e-10 39.6 28.3 6.2e-07 29.2 3.6 5.0 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP10846.1 - 1.1e-07 31.6 25.6 0.00025 21.0 4.4 5.8 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 CEP10846.1 - 0.0081 16.4 15.5 0.025 14.8 3.3 3.5 1 1 1 3 3 3 2 Zinc-finger containing family CNDH2_C PF16858.5 CEP10846.1 - 0.092 12.6 8.3 0.17 11.7 8.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 CEP10846.1 - 1.6 8.0 25.6 2.7 7.3 25.6 1.3 1 0 0 1 1 1 0 SDA1 PUF PF00806.19 CEP10847.1 - 1.9e-56 184.7 15.7 8.4e-09 34.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf_CCCH_4 PF18345.1 CEP10847.1 - 0.0023 17.9 3.0 0.0062 16.6 3.0 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEP10847.1 - 0.0097 15.8 0.5 0.026 14.4 0.5 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Choline_transpo PF04515.12 CEP10848.1 - 4.3e-59 200.3 33.4 4.3e-59 200.3 33.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter TFIIA PF03153.13 CEP10850.1 - 0.022 14.8 10.0 0.022 14.8 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CEP10850.1 - 0.33 10.3 3.4 0.45 9.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex14_N PF04695.13 CEP10850.1 - 0.36 11.5 12.1 0.63 10.7 12.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 CEP10850.1 - 0.39 9.4 5.1 0.4 9.3 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PepSY_TM PF03929.16 CEP10850.1 - 0.58 9.8 2.4 0.69 9.5 2.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CEP10850.1 - 0.73 8.5 3.2 0.96 8.1 3.2 1.1 1 0 0 1 1 1 0 Presenilin DivIC PF04977.15 CEP10850.1 - 5.5 6.8 8.7 0.29 10.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Chromo PF00385.24 CEP10851.1 - 3.2e-09 36.5 1.2 6.4e-09 35.6 1.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP10851.1 - 0.0039 17.4 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 CEP10851.1 - 0.01 15.7 0.6 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF423 PF04241.15 CEP10852.1 - 3.6e-20 72.0 0.1 4.1e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NOA36 PF06524.12 CEP10853.1 - 0.077 12.3 9.9 0.092 12.1 9.9 1.2 1 0 0 1 1 1 0 NOA36 protein Rpr2 PF04032.16 CEP10854.1 - 0.37 11.1 5.6 2.8 8.3 5.6 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Retrotrans_gag PF03732.17 CEP10855.1 - 0.018 15.3 0.4 0.066 13.5 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DLIC PF05783.11 CEP10857.1 - 0.081 11.7 0.6 0.085 11.7 0.6 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SKA1 PF07160.12 CEP10858.1 - 0.0021 18.0 1.2 0.0024 17.7 1.2 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 TolA_bind_tri PF16331.5 CEP10858.1 - 0.0021 18.1 8.0 0.0069 16.4 8.4 1.6 1 1 1 2 2 2 1 TolA binding protein trimerisation Golgin_A5 PF09787.9 CEP10858.1 - 0.0027 17.2 0.5 0.0032 17.0 0.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 GAS PF13851.6 CEP10858.1 - 0.0036 16.7 0.5 0.0047 16.3 0.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 CEP10858.1 - 0.0071 16.7 1.2 0.012 16.0 1.2 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain Allexi_40kDa PF05549.11 CEP10858.1 - 0.0083 15.7 2.3 0.01 15.4 2.3 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein FbpA PF05833.11 CEP10858.1 - 0.0098 14.7 0.4 0.012 14.4 0.4 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FemAB PF02388.16 CEP10858.1 - 0.01 14.7 0.3 0.014 14.3 0.3 1.1 1 0 0 1 1 1 0 FemAB family PRKG1_interact PF15898.5 CEP10858.1 - 0.012 16.5 1.1 0.018 15.9 1.1 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain KfrA_N PF11740.8 CEP10858.1 - 0.012 16.3 1.5 0.017 15.8 1.5 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term MAD PF05557.13 CEP10858.1 - 0.016 13.6 1.3 0.019 13.3 1.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Cluap1 PF10234.9 CEP10858.1 - 0.029 13.8 0.7 0.037 13.4 0.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc24 PF08286.11 CEP10858.1 - 0.045 14.0 0.9 0.064 13.5 0.9 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 CEP10858.1 - 0.07 13.2 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YPEB PF14620.6 CEP10858.1 - 0.077 12.3 0.7 0.094 12.0 0.7 1.1 1 0 0 1 1 1 0 YpeB sporulation NEMO PF11577.8 CEP10858.1 - 0.086 12.9 1.5 0.15 12.1 1.5 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF2630 PF10944.8 CEP10858.1 - 0.1 13.0 3.2 0.18 12.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DUF3450 PF11932.8 CEP10858.1 - 0.13 11.5 6.0 0.18 11.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.6 CEP10858.1 - 0.26 11.4 0.1 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain JIP_LZII PF16471.5 CEP10858.1 - 0.27 11.5 3.3 0.44 10.8 3.3 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF4349 PF14257.6 CEP10858.1 - 0.28 10.6 2.6 0.47 9.9 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Cnn_1N PF07989.11 CEP10858.1 - 0.37 11.0 3.8 0.55 10.4 3.8 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 CEP10858.1 - 0.39 10.9 5.0 0.62 10.2 5.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2968 PF11180.8 CEP10858.1 - 0.73 9.4 8.2 1 9.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SseC PF04888.12 CEP10858.1 - 3.8 7.0 4.8 4.8 6.7 4.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family RVT_1 PF00078.27 CEP10860.1 - 4.7e-42 144.0 0.0 7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPACA9 PF15120.6 CEP10860.1 - 0.13 12.1 3.3 6.8 6.4 0.3 3.3 4 0 0 4 4 4 0 Sperm acrosome-associated protein 9 RT_RNaseH_2 PF17919.1 CEP10861.1 - 1.3e-25 89.3 0.1 2.3e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP10861.1 - 9.7e-22 77.2 0.1 2.1e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_3 PF13358.6 CEP10862.1 - 1.5e-18 67.0 0.0 9.7e-15 54.6 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease rve PF00665.26 CEP10862.1 - 0.042 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Helitron_like_N PF14214.6 CEP10863.1 - 6.3e-22 78.7 0.0 1.7e-21 77.3 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Ribosomal_L31e PF01198.19 CEP10863.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L31e DDE_3 PF13358.6 CEP10864.1 - 1.6e-06 28.0 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TFIIA_gamma_C PF02751.14 CEP10864.1 - 0.0036 17.4 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DDE_3 PF13358.6 CEP10865.1 - 9.2e-06 25.5 0.0 0.0003 20.5 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HLH PF00010.26 CEP10867.1 - 3.7e-13 49.2 1.1 3.7e-13 49.2 1.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain 6PF2K PF01591.18 CEP10868.1 - 1.8e-78 262.9 0.2 2.3e-78 262.5 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP10868.1 - 6.3e-24 84.7 0.0 1.7e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEP10868.1 - 0.0077 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ribosomal_L27e PF01777.18 CEP10870.1 - 4.4e-37 126.3 7.8 4.4e-37 126.3 7.8 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CEP10870.1 - 0.0035 17.2 6.9 0.009 15.9 6.9 1.9 1 1 0 1 1 1 1 KOW motif FKBP_C PF00254.28 CEP10871.1 - 1e-29 102.6 0.1 3.6e-29 100.9 0.0 2.0 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CEP10871.1 - 1.8e-26 92.7 0.1 1.8e-26 92.7 0.1 2.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain RRM_1 PF00076.22 CEP10871.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 CEP10871.1 - 0.04 12.1 35.6 0.053 11.8 35.6 1.1 1 0 0 1 1 1 0 Nop14-like family XRCC4 PF06632.12 CEP10871.1 - 0.18 10.6 27.5 0.29 9.9 27.5 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4772 PF15997.5 CEP10871.1 - 0.18 12.4 2.8 0.72 10.5 1.5 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4772) Presenilin PF01080.17 CEP10871.1 - 0.77 8.5 14.3 1 8.1 14.3 1.2 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CEP10871.1 - 2 7.1 16.5 2.7 6.7 16.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Amidase PF01425.21 CEP10873.1 - 1.8e-123 412.8 0.1 1.1e-113 380.6 0.0 2.0 2 0 0 2 2 2 2 Amidase NAD_synthase PF02540.17 CEP10873.1 - 0.25 10.4 0.4 0.51 9.4 0.4 1.4 1 0 0 1 1 1 0 NAD synthase OrfB_Zn_ribbon PF07282.11 CEP10874.1 - 0.32 10.9 2.5 1 9.3 2.5 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain RhoGAP PF00620.27 CEP10876.1 - 5.8e-45 152.8 0.3 5.8e-45 152.8 0.3 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CEP10876.1 - 2e-18 66.4 28.4 7e-10 39.0 6.7 2.7 2 0 0 2 2 2 2 LIM domain NYD-SP28_assoc PF14775.6 CEP10876.1 - 0.34 11.1 7.7 0.18 11.9 1.2 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain Prefoldin_2 PF01920.20 CEP10876.1 - 0.59 10.1 13.2 0.54 10.2 0.5 4.1 3 0 0 3 3 3 0 Prefoldin subunit DUF5464 PF17552.2 CEP10877.1 - 0.18 12.1 0.2 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) ELO PF01151.18 CEP10878.1 - 6.4e-68 229.0 9.6 7.6e-68 228.7 9.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.8 CEP10878.1 - 0.21 11.7 1.4 1.7 8.7 0.3 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 4HBT PF03061.22 CEP10879.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily WD40 PF00400.32 CEP10880.1 - 0.03 15.2 9.9 5.4 8.1 0.1 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat RRM_1 PF00076.22 CEP10881.1 - 1.5e-15 56.8 0.1 2.1e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP10881.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Spo0M PF07070.11 CEP10882.1 - 2.7e-05 23.8 0.1 0.055 13.0 0.1 2.3 2 0 0 2 2 2 2 SpoOM protein Arrestin_N PF00339.29 CEP10882.1 - 0.0029 17.7 0.1 0.032 14.3 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP10882.1 - 0.003 18.0 9.2 0.0033 17.9 4.3 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain zf-RING_2 PF13639.6 CEP10883.1 - 6.5e-13 48.8 7.3 6.5e-13 48.8 7.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CEP10883.1 - 1.3e-08 34.4 5.8 1.3e-08 34.4 5.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEP10883.1 - 2.5e-08 33.6 8.0 2.5e-08 33.6 8.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP10883.1 - 5.9e-08 32.9 7.7 5.9e-08 32.9 7.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEP10883.1 - 9.1e-08 31.9 6.3 9.1e-08 31.9 6.3 2.4 2 1 1 3 3 3 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 CEP10883.1 - 1.5e-07 31.6 3.1 1.5e-07 31.6 3.1 2.7 3 0 0 3 3 3 1 zinc-ribbon zf-RING_UBOX PF13445.6 CEP10883.1 - 2.6e-06 27.3 3.1 2.6e-06 27.3 3.1 2.5 2 2 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP10883.1 - 5.7e-06 26.1 7.9 5.7e-06 26.1 7.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP10883.1 - 1.1e-05 25.2 5.1 1.1e-05 25.2 5.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP10883.1 - 2.5e-05 24.0 7.4 7.4e-05 22.5 7.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP10883.1 - 0.00025 21.0 2.3 0.00064 19.7 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CEP10883.1 - 0.0025 17.6 0.2 0.0052 16.6 0.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CEP10883.1 - 0.0037 16.8 4.6 0.0037 16.8 4.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HypA PF01155.19 CEP10883.1 - 0.076 13.0 8.3 2.3 8.3 2.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rtf2 PF04641.12 CEP10883.1 - 2.4 7.4 13.4 0.63 9.3 9.5 2.0 2 1 0 2 2 2 0 Rtf2 RING-finger Vps39_2 PF10367.9 CEP10883.1 - 2.7 8.5 7.6 0.22 12.0 0.5 2.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 DUF983 PF06170.12 CEP10883.1 - 2.7 8.5 3.4 55 4.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-RING_10 PF16685.5 CEP10883.1 - 3.4 7.9 9.6 1.3 9.2 4.2 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 CEP10883.1 - 3.5 7.7 11.1 4.7 7.3 0.8 2.8 2 1 0 2 2 2 0 Double zinc ribbon Med13_C PF06333.12 CEP10884.1 - 1.6e-52 178.9 1.8 1.6e-52 178.9 1.8 5.9 5 2 1 6 6 6 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 CEP10884.1 - 4.6e-21 75.7 0.0 1.4e-12 47.9 0.0 6.1 3 2 1 4 4 4 2 MID domain of medPIWI Toxin_35 PF10530.9 CEP10885.1 - 0.00043 20.2 0.1 0.0006 19.7 0.1 1.3 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold EDR1 PF14381.6 CEP10886.1 - 0.035 13.8 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 zf-TFIIIC PF12660.7 CEP10887.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Pap_E4 PF02711.14 CEP10887.1 - 1.3 10.0 7.2 0.34 11.9 3.5 1.9 1 1 1 2 2 2 0 E4 protein RRM_1 PF00076.22 CEP10888.1 - 8.9e-14 51.1 2.0 5.3e-10 39.0 0.3 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP10888.1 - 0.031 14.3 0.7 0.6 10.2 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 CEP10888.1 - 0.037 14.0 37.9 0.68 9.9 30.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_occluded PF16842.5 CEP10888.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Iso_dh PF00180.20 CEP10889.1 - 1.2e-101 340.3 0.1 1.4e-101 340.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DBD_Tnp_Mut PF03108.15 CEP10890.1 - 0.00044 20.2 2.5 0.0013 18.7 0.5 2.7 3 0 0 3 3 3 1 MuDR family transposase FAR1 PF03101.15 CEP10890.1 - 0.0015 19.2 1.0 0.0033 18.1 1.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Arginosuc_synth PF00764.19 CEP10891.1 - 2.6e-152 507.6 0.0 3.1e-152 507.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CEP10891.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CEP10891.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DDE_3 PF13358.6 CEP10892.1 - 1.5e-09 37.8 0.8 2.6e-09 37.0 0.8 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP10892.1 - 0.022 13.8 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain p450 PF00067.22 CEP10893.1 - 4.8e-70 236.6 0.2 6.2e-70 236.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 GrlR PF16518.5 CEP10893.1 - 0.067 13.2 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 T3SS negative regulator,GrlR Cyclin_N PF00134.23 CEP10894.1 - 4.9e-07 29.5 0.2 9.7e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP10894.1 - 0.0018 18.7 0.3 0.0025 18.2 0.3 1.3 1 1 0 1 1 1 1 Cyclin RRS1 PF04939.12 CEP10895.1 - 1.4e-55 187.6 3.6 1.4e-55 187.6 3.6 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) IU_nuc_hydro PF01156.19 CEP10896.1 - 4.7e-11 42.8 0.0 5.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase gag-asp_proteas PF13975.6 CEP10898.1 - 3.3e-05 24.4 0.6 0.043 14.4 0.0 3.3 2 1 1 3 3 3 2 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CEP10898.1 - 0.00025 21.0 4.8 0.00045 20.2 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CEP10898.1 - 0.0022 18.6 0.4 0.021 15.5 0.0 2.6 2 1 1 3 3 3 1 Aspartyl protease RVP_2 PF08284.11 CEP10898.1 - 0.018 14.8 0.0 4.3 7.1 0.0 2.5 1 1 1 2 2 2 0 Retroviral aspartyl protease CpXC PF14353.6 CEP10898.1 - 0.13 12.3 3.3 0.22 11.6 1.6 2.3 2 0 0 2 2 2 0 CpXC protein zf-CCHC_5 PF14787.6 CEP10898.1 - 0.59 9.9 2.5 1.5 8.6 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4196 PF13846.6 CEP10898.1 - 1.5 9.0 9.7 24 5.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) RVT_1 PF00078.27 CEP10899.1 - 7e-05 22.5 1.3 0.00021 20.9 0.4 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MATalpha_HMGbox PF04769.12 CEP10899.1 - 0.031 13.6 0.5 0.034 13.5 0.5 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Phtf-FEM1B_bdg PF12129.8 CEP10899.1 - 0.061 13.2 0.3 0.092 12.6 0.2 1.3 1 1 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Integrase_H2C2 PF17921.1 CEP10900.1 - 1.4e-16 60.3 0.0 2.6e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP10900.1 - 0.0017 18.5 0.0 0.0044 17.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 CEP10901.1 - 2.7e-07 30.8 0.0 6.6e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 Integrase core domain AbiEi_1 PF09407.10 CEP10902.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain Asp_protease_2 PF13650.6 CEP10902.1 - 0.15 12.8 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 CEP10902.1 - 0.15 12.2 2.1 0.52 10.5 2.1 2.0 1 0 0 1 1 1 0 Zinc knuckle DUF4718 PF15842.5 CEP10903.1 - 0.53 10.1 3.4 0.63 9.8 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Helitron_like_N PF14214.6 CEP10906.1 - 4.5e-35 121.6 0.0 5.5e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP10912.1 - 4.6e-14 52.4 0.0 5.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF2122 PF09895.9 CEP10912.1 - 0.034 14.5 0.0 0.062 13.7 0.0 1.4 1 1 0 1 1 1 0 RecB-family nuclease (DUF2122) PIF1 PF05970.14 CEP10913.1 - 1.7e-06 27.5 0.0 1.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase HTH_23 PF13384.6 CEP10915.1 - 0.015 15.1 0.1 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF496 PF04363.12 CEP10915.1 - 0.03 14.3 0.2 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HTH_17 PF12728.7 CEP10915.1 - 0.062 13.5 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CEP10915.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 CEP10915.1 - 0.081 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 CEP10915.1 - 0.095 13.3 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain MerR_1 PF13411.6 CEP10915.1 - 0.24 11.5 1.8 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF2052 PF09747.9 CEP10916.1 - 1e-37 130.2 26.0 1e-37 130.2 26.0 1.5 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF5388 PF17363.2 CEP10917.1 - 0.0068 16.6 0.1 0.035 14.3 0.1 2.3 1 0 0 1 1 1 1 Family of unknown function (DUF5388) HSF_DNA-bind PF00447.17 CEP10918.1 - 1.7e-32 111.8 1.1 1.7e-32 111.8 1.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Cdc6_C PF09079.11 CEP10918.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RhoGEF PF00621.20 CEP10919.1 - 5.2e-17 62.7 7.6 7.6e-17 62.1 1.7 3.0 2 1 1 3 3 3 1 RhoGEF domain IQ_SEC7_PH PF16453.5 CEP10919.1 - 0.0075 16.2 0.5 0.078 13.0 0.0 2.9 3 0 0 3 3 3 1 PH domain PH PF00169.29 CEP10919.1 - 0.03 14.8 0.0 3.4 8.2 0.0 2.9 2 0 0 2 2 2 0 PH domain PH_10 PF15411.6 CEP10919.1 - 0.29 11.4 0.0 0.29 11.4 0.0 3.6 5 1 0 5 5 5 0 Pleckstrin homology domain GFO_IDH_MocA PF01408.22 CEP10920.1 - 1.3e-20 74.4 1.3 3.9e-20 72.9 1.3 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 CEP10920.1 - 0.0015 18.6 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CEP10920.1 - 0.0019 18.7 0.9 0.018 15.6 0.0 2.7 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 CEP10920.1 - 0.021 14.8 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain XPG_I_2 PF12813.7 CEP10920.1 - 0.093 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing Glyco_transf_15 PF01793.16 CEP10921.1 - 7.1e-107 357.4 11.4 8.3e-107 357.2 11.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sarcoglycan_2 PF05510.13 CEP10922.1 - 0.07 11.9 0.1 0.84 8.3 0.1 2.2 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Ank_2 PF12796.7 CEP10923.1 - 1.8e-19 70.1 7.3 9.6e-08 32.5 0.4 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP10923.1 - 1.8e-13 50.7 2.4 1.1e-06 29.1 0.7 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEP10923.1 - 4.1e-11 42.8 1.8 2.4e-05 24.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP10923.1 - 1.1e-10 41.6 0.1 0.016 15.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP10923.1 - 5.3e-10 38.7 2.1 0.0084 16.5 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat YceG_bac PF14266.6 CEP10925.1 - 0.076 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' Cullin PF00888.22 CEP10928.1 - 1.4e-143 479.8 19.6 2.2e-143 479.1 19.6 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEP10928.1 - 2.5e-18 65.8 1.1 2.5e-18 65.8 1.1 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3848 PF12959.7 CEP10928.1 - 0.06 13.4 0.6 0.34 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Glyco_hydro_4C PF11975.8 CEP10928.1 - 0.11 12.5 1.3 0.3 11.1 1.3 1.7 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain WAC_Acf1_DNA_bd PF10537.9 CEP10928.1 - 0.91 10.1 4.0 1.2 9.7 0.3 3.0 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal SVIP PF15811.5 CEP10928.1 - 3.8 8.0 4.6 25 5.4 0.5 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein TRAPPC10 PF12584.8 CEP10929.1 - 8.9e-18 64.5 0.0 2.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 CEP10929.1 - 0.0014 18.5 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking T6SS_VasJ PF16989.5 CEP10929.1 - 0.096 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ GATase_6 PF13522.6 CEP10930.1 - 5.5e-15 55.7 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEP10930.1 - 3.6e-12 46.3 0.0 7.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CEP10930.1 - 3.6e-06 26.1 0.0 7.9e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 CEP10930.1 - 1.1e-05 25.0 0.1 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2118 PF09891.9 CEP10930.1 - 0.074 13.0 0.4 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Nro1 PF12753.7 CEP10931.1 - 1.4e-15 57.1 12.5 5.2e-14 52.0 0.1 2.1 1 1 1 2 2 2 2 Nuclear pore complex subunit Nro1 TPR_16 PF13432.6 CEP10931.1 - 0.0024 18.5 1.7 5.6 7.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP10931.1 - 0.0063 16.8 2.7 5.4 7.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat OMS28_porin PF03532.13 CEP10931.1 - 0.041 13.1 2.2 0.63 9.2 0.0 2.3 2 0 0 2 2 2 0 OMS28 porin TPR_11 PF13414.6 CEP10931.1 - 0.048 13.3 0.5 2.3 8.0 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 CEP10931.1 - 0.14 13.0 5.4 26 6.0 0.0 4.4 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEP10931.1 - 0.39 11.3 7.6 6.4 7.4 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP10931.1 - 1.6 9.2 8.8 13 6.3 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat 7TMR-HDED PF07697.11 CEP10931.1 - 2 8.5 10.7 0.66 10.1 7.7 2.0 1 1 1 2 2 2 0 7TM-HD extracellular zinc-ribbons_6 PF07191.12 CEP10932.1 - 0.13 12.3 10.6 0.78 9.8 0.9 2.2 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_12 PF11331.8 CEP10932.1 - 5.7 6.8 0.0 5.7 6.8 0.0 3.0 3 1 0 3 3 3 0 Probable zinc-ribbon domain RPAP1_C PF08620.10 CEP10933.1 - 6.4e-26 90.3 1.5 1.3e-24 86.1 0.1 2.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CEP10933.1 - 5.1e-09 35.8 3.0 1.8e-08 34.0 3.0 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal AAA PF00004.29 CEP10934.1 - 3.6e-06 27.5 0.2 0.00074 19.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEP10934.1 - 0.0048 16.8 0.3 0.26 11.2 0.1 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain DEC-1_N PF04625.13 CEP10934.1 - 0.026 13.6 6.4 0.044 12.8 6.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DNA_pol3_delta PF06144.13 CEP10934.1 - 0.13 12.0 0.5 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RhoGAP PF00620.27 CEP10935.1 - 3.9e-35 120.9 0.4 1.5e-34 119.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CEP10935.1 - 4.8e-22 77.9 49.0 3.5e-11 43.1 9.9 5.0 4 1 0 4 4 4 4 LIM domain DUF359 PF04019.12 CEP10935.1 - 0.078 12.6 0.1 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF359) ANAPC8 PF04049.13 CEP10935.1 - 0.08 13.0 1.2 0.21 11.6 1.2 1.6 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 DUF1387 PF07139.11 CEP10935.1 - 1.3 8.7 8.7 0.26 11.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Dynamin_M PF01031.20 CEP10936.1 - 1.4e-102 342.8 0.0 2.4e-100 335.4 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region VPS28 PF03997.12 CEP10936.1 - 1.9e-58 197.3 2.4 3.7e-58 196.3 2.4 1.4 1 0 0 1 1 1 1 VPS28 protein Dynamin_N PF00350.23 CEP10936.1 - 2.5e-53 180.6 0.6 5.7e-53 179.4 0.1 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CEP10936.1 - 2.9e-27 94.7 0.1 1.2e-26 92.6 0.1 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEP10936.1 - 3.1e-05 24.0 0.0 0.064 13.3 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase OAM_alpha PF16552.5 CEP10936.1 - 0.019 14.8 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit Roc PF08477.13 CEP10936.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TipAS PF07739.13 CEP10936.1 - 0.13 12.8 0.1 0.68 10.5 0.0 2.3 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain CCDC66 PF15236.6 CEP10936.1 - 0.22 11.3 3.8 0.43 10.4 3.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Tim17 PF02466.19 CEP10937.1 - 6.4e-37 126.3 9.1 7.7e-37 126.1 9.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABA_WDS PF02496.16 CEP10937.1 - 0.78 10.3 3.7 18 5.9 3.7 2.9 1 1 0 1 1 1 0 ABA/WDS induced protein Aminotran_5 PF00266.19 CEP10938.1 - 3.1e-24 85.6 0.0 3.7e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 CEP10939.1 - 5.1e-36 124.3 29.4 5.1e-36 124.3 29.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CEP10939.1 - 5.9e-07 29.1 9.6 5.9e-07 29.1 9.6 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RRM_1 PF00076.22 CEP10940.1 - 3.6e-17 62.0 0.2 5.2e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP10940.1 - 0.00034 20.2 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP10940.1 - 0.00037 20.3 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CEP10940.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 CEP10940.1 - 0.0076 16.3 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif PMC2NT PF08066.12 CEP10940.1 - 2.1 9.1 6.5 5.2 7.8 1.3 2.5 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Pkinase PF00069.25 CEP10941.1 - 1.1e-36 126.6 0.0 1.9e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10941.1 - 3.4e-32 111.8 0.0 5.1e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 CEP10941.1 - 7.1e-07 28.8 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF2753 PF10952.8 CEP10941.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) APH PF01636.23 CEP10941.1 - 0.014 15.4 0.0 0.043 13.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP10941.1 - 0.033 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AP3B1_C PF14796.6 CEP10941.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Rho_N PF07498.12 CEP10941.1 - 0.093 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Kdo PF06293.14 CEP10941.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 CEP10942.1 - 2.1e-15 56.3 0.3 1.3e-11 44.2 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP10942.1 - 0.096 12.8 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif zf-CHY PF05495.12 CEP10943.1 - 2.5e-09 37.5 16.5 2.5e-09 37.5 16.5 4.0 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 CEP10943.1 - 0.0011 19.2 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 RWD domain DASH_Dad1 PF08649.10 CEP10943.1 - 0.0079 16.4 0.6 0.91 9.8 0.1 2.4 2 0 0 2 2 2 2 DASH complex subunit Dad1 CLTH PF10607.9 CEP10944.1 - 1.9e-37 128.4 0.7 5e-37 127.1 0.7 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CEP10944.1 - 0.019 15.0 1.7 3.3 7.8 0.0 3.2 3 0 0 3 3 3 0 RING-type zinc-finger zf-Di19 PF05605.12 CEP10944.1 - 0.082 13.2 0.5 0.28 11.5 0.5 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Mitofilin PF09731.9 CEP10944.1 - 0.14 11.0 5.6 0.1 11.4 4.4 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Prok-RING_4 PF14447.6 CEP10944.1 - 8.3 6.4 8.7 0.13 12.2 0.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 GATA PF00320.27 CEP10945.1 - 7e-30 102.3 13.4 5e-15 54.8 4.4 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CEP10945.1 - 5.3e-12 45.3 0.5 1.7e-11 43.7 0.5 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 CEP10945.1 - 0.00078 19.5 3.8 0.47 10.6 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEP10945.1 - 0.0028 17.1 4.3 0.39 10.3 0.3 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CEP10945.1 - 0.036 14.2 6.9 0.68 10.1 0.8 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OTT_1508_deam PF14441.6 CEP10945.1 - 0.071 13.1 0.1 23 5.1 0.0 2.7 2 0 0 2 2 2 0 OTT_1508-like deaminase OrfB_Zn_ribbon PF07282.11 CEP10945.1 - 0.1 12.6 9.0 0.37 10.7 1.0 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 CEP10945.1 - 0.11 12.5 9.3 1.8 8.7 0.7 3.1 1 1 2 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 CEP10945.1 - 0.43 10.5 4.2 12 5.8 0.4 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FAM163 PF15069.6 CEP10945.1 - 0.5 10.8 9.3 1.5 9.3 0.4 2.9 2 1 1 3 3 3 0 FAM163 family DUF3039 PF11238.8 CEP10945.1 - 2.2 8.1 4.2 40 4.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zinc_ribbon_2 PF13240.6 CEP10945.1 - 2.3 8.1 8.5 20 5.1 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEP10945.1 - 3.7 7.1 11.0 5.9 6.4 0.7 4.3 4 0 0 4 4 4 0 zinc-ribbon domain 4HBT_3 PF13622.6 CEP10946.1 - 2.4e-29 103.3 0.0 2.8e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily FMN_red PF03358.15 CEP10947.1 - 2.8e-33 114.8 0.0 4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEP10947.1 - 8.5e-12 45.2 0.1 1.3e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin-like fold RRM_1 PF00076.22 CEP10948.1 - 3e-13 49.4 0.0 6.1e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP10948.1 - 0.0027 17.7 1.0 0.0071 16.4 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif Apt1 PF10351.9 CEP10948.1 - 0.9 8.3 9.6 0.98 8.2 9.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CEP10948.1 - 6.2 5.5 8.9 7.8 5.2 8.9 1.2 1 0 0 1 1 1 0 Presenilin Ubiquitin_2 PF14560.6 CEP10949.1 - 8.6e-27 93.4 0.0 1.8e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CEP10949.1 - 3.8e-25 87.7 2.0 4.7e-25 87.4 1.3 1.5 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 CEP10949.1 - 0.004 16.9 0.2 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family D123 PF07065.14 CEP10949.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 D123 Homeodomain PF00046.29 CEP10951.1 - 2.5e-14 52.8 2.4 2.5e-14 52.8 2.4 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CEP10951.1 - 0.0047 16.8 0.1 0.021 14.7 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain SR-25 PF10500.9 CEP10951.1 - 0.009 15.6 5.7 0.009 15.6 5.7 2.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein HTH_23 PF13384.6 CEP10951.1 - 0.024 14.4 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DUF4451 PF14616.6 CEP10952.1 - 6.3e-16 58.7 0.2 6.3e-16 58.7 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Raptor_N PF14538.6 CEP10953.1 - 0.034 14.1 0.1 6.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain MAT1 PF06391.13 CEP10954.1 - 3.6e-45 154.3 31.5 5.3e-43 147.2 31.5 2.1 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CEP10954.1 - 1.8e-20 72.6 7.0 3.6e-20 71.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP10954.1 - 5.7e-07 29.3 6.2 1.6e-06 27.9 6.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP10954.1 - 1.1e-06 28.5 8.1 9.6e-06 25.5 8.6 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEP10954.1 - 7e-06 26.3 7.3 1.6e-05 25.1 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEP10954.1 - 8.4e-06 25.6 6.1 2.6e-05 24.0 6.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP10954.1 - 0.00011 21.9 10.1 0.00054 19.7 10.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP10954.1 - 0.00021 21.1 10.9 0.009 15.8 11.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEP10954.1 - 0.00027 20.9 8.0 0.002 18.1 3.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CEP10954.1 - 0.00062 19.5 4.3 0.031 14.1 1.5 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain GAGA PF09237.11 CEP10954.1 - 0.0033 17.2 9.4 0.028 14.2 1.2 3.4 3 0 0 3 3 3 1 GAGA factor Selenoprotein_S PF06936.11 CEP10954.1 - 0.0046 16.8 11.0 0.0077 16.1 11.0 1.3 1 0 0 1 1 1 1 Selenoprotein S (SelS) Ureide_permease PF07168.11 CEP10954.1 - 0.11 11.2 2.9 0.17 10.6 2.9 1.2 1 0 0 1 1 1 0 Ureide permease UPF0242 PF06785.11 CEP10954.1 - 0.22 11.6 11.4 0.33 11.0 11.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-WRNIP1_ubi PF18279.1 CEP10954.1 - 0.26 12.0 5.7 8.2 7.3 1.0 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 CEP10954.1 - 0.37 10.9 2.2 0.69 10.0 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 CEP10954.1 - 0.45 10.7 4.3 10 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 CEP10954.1 - 0.79 9.6 9.6 6.7 6.6 0.0 4.2 4 1 0 5 5 5 0 Rad50 zinc hook motif DUF3797 PF12677.7 CEP10954.1 - 2.2 8.2 5.1 0.31 10.9 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) SRP19 PF01922.17 CEP10955.1 - 5.9e-30 104.1 0.2 1.2e-29 103.1 0.2 1.5 1 0 0 1 1 1 1 SRP19 protein Forkhead_N PF08430.12 CEP10955.1 - 0.2 12.3 15.2 0.096 13.3 12.3 1.8 2 0 0 2 2 2 0 Forkhead N-terminal region EMP24_GP25L PF01105.24 CEP10956.1 - 2e-38 132.1 1.6 2.8e-38 131.7 1.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1344 PF07076.11 CEP10956.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF1408 PF07193.11 CEP10956.1 - 0.087 13.0 0.3 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) Pkinase PF00069.25 CEP10957.1 - 1.9e-46 158.6 0.0 3.7e-46 157.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP10957.1 - 1.5e-20 73.6 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP10957.1 - 8.1e-06 25.9 0.0 2.2e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP10957.1 - 0.00086 18.7 0.0 0.0033 16.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEP10957.1 - 0.0011 18.0 0.1 0.0027 16.7 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain DUF1687 PF07955.11 CEP10958.1 - 3.7e-16 59.8 0.2 6.1e-16 59.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 CEP10958.1 - 9.6e-06 25.5 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 ArsC family HTH_3 PF01381.22 CEP10958.1 - 0.022 14.8 0.0 6.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Aconitase PF00330.20 CEP10959.1 - 3.7e-154 514.1 0.0 4.6e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP10959.1 - 6.1e-42 143.1 0.0 1.1e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CEP10959.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) NDC10_II PF16787.5 CEP10960.1 - 3.7e-20 72.2 0.0 7.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP10960.1 - 0.015 15.6 0.2 0.038 14.3 0.2 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes MAD PF05557.13 CEP10960.1 - 0.14 10.5 0.1 0.17 10.2 0.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cas_Cmr5 PF09701.10 CEP10961.1 - 0.082 13.2 0.4 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) OspE PF02471.17 CEP10961.1 - 0.11 12.8 1.0 8 6.7 0.0 2.9 2 2 1 3 3 3 0 Borrelia outer surface protein E MIS13 PF08202.11 CEP10962.1 - 2.2e-16 60.1 6.1 5.8e-16 58.7 6.2 1.6 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Tap-RNA_bind PF09162.10 CEP10962.1 - 0.0091 15.8 0.3 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 Tap, RNA-binding ELM2 PF01448.24 CEP10962.1 - 0.12 13.1 1.0 10 7.0 1.0 2.7 1 1 0 1 1 1 0 ELM2 domain zf-RVT PF13966.6 CEP10963.1 - 5.3e-08 33.5 1.5 1.5e-07 32.1 1.5 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP10963.1 - 3.8e-07 29.8 0.0 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.28 CEP10964.1 - 1.8e-37 129.9 0.4 2.7e-37 129.3 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP10964.1 - 0.00022 21.6 0.2 0.00044 20.6 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain cwf21 PF08312.12 CEP10964.1 - 0.3 11.3 1.7 0.52 10.5 1.7 1.4 1 0 0 1 1 1 0 cwf21 domain Ribosomal_L1 PF00687.21 CEP10965.1 - 6.8e-33 114.1 1.2 7.5e-33 114.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 CEP10965.1 - 0.11 12.6 3.3 0.17 12.0 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function Dynamin_N PF00350.23 CEP10966.1 - 3.2e-05 24.1 3.2 0.00017 21.7 3.2 2.2 1 1 0 1 1 1 1 Dynamin family Myc_N PF01056.18 CEP10966.1 - 0.093 12.6 2.8 0.21 11.5 2.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Gal4_dimer PF03902.13 CEP10968.1 - 0.19 11.9 0.5 0.35 11.1 0.5 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain HTH_Tnp_Tc3_2 PF01498.18 CEP10971.1 - 1.4e-10 41.2 0.1 4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_40 PF14493.6 CEP10971.1 - 0.0069 16.8 0.0 0.021 15.3 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP10971.1 - 0.035 14.1 0.2 0.035 14.1 0.2 2.0 3 0 0 3 3 3 0 Winged helix-turn helix fn2 PF00040.19 CEP10971.1 - 0.27 11.5 5.2 0.41 11.0 2.3 2.5 2 0 0 2 2 2 0 Fibronectin type II domain zf-CCHC PF00098.23 CEP10972.1 - 1.5e-05 24.8 4.3 2.9e-05 23.9 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEP10972.1 - 0.037 13.8 4.0 0.062 13.1 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEP10972.1 - 0.065 13.1 0.6 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 CEP10972.1 - 0.083 13.3 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RVT_1 PF00078.27 CEP10973.1 - 2.5e-14 53.3 1.1 1.3e-10 41.2 0.7 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP10974.1 - 1.5e-26 92.7 0.5 5.1e-26 91.0 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP10974.1 - 1.7e-25 89.0 0.0 5.7e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP10974.1 - 3e-13 50.0 0.0 5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 CEP10974.1 - 0.00047 20.2 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Syncollin PF15138.6 CEP10974.1 - 0.027 14.7 0.3 6.3 7.0 0.1 2.7 2 0 0 2 2 2 0 Syncollin Integrase_H2C2 PF17921.1 CEP10974.1 - 0.031 14.4 0.2 0.082 13.0 0.2 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain rve_3 PF13683.6 CEP10974.1 - 0.085 12.6 0.6 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain F-box-like PF12937.7 CEP10975.1 - 1.5e-05 24.8 1.6 4.3e-05 23.3 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP10975.1 - 0.061 13.2 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box domain NTP_transf_2 PF01909.23 CEP10976.1 - 2.8e-07 30.7 0.7 1.1e-06 28.8 0.0 2.4 3 0 0 3 3 3 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEP10976.1 - 0.00012 22.3 0.1 0.00033 20.8 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Connexin PF00029.19 CEP10976.1 - 0.78 9.5 2.9 1.6 8.5 2.9 1.4 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 CEP10976.1 - 2.2 6.5 9.0 3.4 5.9 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CEP10976.1 - 2.3 6.3 16.1 3.7 5.6 16.1 1.2 1 0 0 1 1 1 0 Nop14-like family Mak16 PF04874.14 CEP10976.1 - 2.8 8.6 14.9 8.3 7.1 14.9 1.7 1 0 0 1 1 1 0 Mak16 protein C-terminal region SDA1 PF05285.12 CEP10976.1 - 8.3 5.7 13.8 15 4.9 13.8 1.4 1 0 0 1 1 1 0 SDA1 Glyco_trans_2_3 PF13632.6 CEP10977.1 - 7.9e-16 58.5 0.7 7.9e-16 58.5 0.7 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PQ-loop PF04193.14 CEP10978.1 - 5e-28 96.6 8.3 5e-14 51.8 0.4 3.0 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CEP10978.1 - 0.02 14.9 5.7 0.14 12.2 0.4 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4181 PF13789.6 CEP10978.1 - 0.32 11.3 4.0 0.16 12.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Peptidase_A6 PF01829.16 CEP10979.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase A6 family PRK PF00485.18 CEP10980.1 - 7.6e-06 25.8 0.0 2.8e-05 23.9 0.0 1.9 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 CEP10980.1 - 0.001 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.14 CEP10980.1 - 0.0011 18.9 0.1 0.012 15.5 0.0 2.5 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CEP10980.1 - 0.0013 19.3 0.0 0.0039 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP10980.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP10980.1 - 0.0025 18.2 0.0 0.0037 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CEP10980.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 CEP10980.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CEP10980.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CEP10980.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.14 CEP10980.1 - 0.013 14.7 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.17 CEP10980.1 - 0.013 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 CEP10980.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CEP10980.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CEP10980.1 - 0.059 12.5 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 CEP10980.1 - 0.059 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CEP10980.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CEP10980.1 - 0.065 13.8 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Thymidylate_kin PF02223.17 CEP10980.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 CEP10980.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CEP10980.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase PWWP PF00855.17 CEP10981.1 - 3e-18 66.0 0.0 3e-18 66.0 0.0 3.2 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 CEP10981.1 - 1.2e-08 34.9 0.0 2.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Sugar_tr PF00083.24 CEP10983.1 - 1.6e-129 432.7 31.2 1.9e-129 432.5 31.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP10983.1 - 5.2e-25 88.1 42.5 1.6e-17 63.5 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBS PF00571.28 CEP10984.1 - 3.7e-27 94.6 2.1 2.2e-06 28.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain IF3_N PF05198.16 CEP10984.1 - 0.14 12.4 0.1 8.4 6.8 0.1 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain FF PF01846.19 CEP10985.1 - 9.6e-31 105.7 15.0 2.7e-14 53.1 2.9 3.5 3 0 0 3 3 3 3 FF domain WW PF00397.26 CEP10985.1 - 4.2e-14 52.3 9.1 4.6e-09 36.2 3.5 2.7 2 0 0 2 2 2 2 WW domain PDZ_5 PF17817.1 CEP10986.1 - 0.093 13.0 0.1 6.7 7.1 0.0 2.1 2 0 0 2 2 2 0 PDZ domain SNF2_N PF00176.23 CEP10987.1 - 1.9e-71 240.7 1.8 1.9e-71 240.7 1.8 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP10987.1 - 4.3e-23 81.8 0.1 3.8e-20 72.3 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 CEP10987.1 - 6.2e-20 71.3 10.4 6.2e-20 71.3 10.4 2.8 2 0 0 2 2 2 1 HSA SnAC PF14619.6 CEP10987.1 - 1.8e-14 54.1 1.3 1.8e-14 54.1 1.3 3.9 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 CEP10987.1 - 4.4e-11 42.3 6.5 4.4e-11 42.3 6.5 2.1 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 CEP10987.1 - 1.1e-09 38.5 4.9 3e-09 37.1 0.1 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 CEP10987.1 - 1.9e-06 27.8 0.1 6.5e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 Bromodomain CHU_C PF13585.6 CEP10987.1 - 0.043 13.9 0.1 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Ribosomal_L1 PF00687.21 CEP10989.1 - 2.5e-45 154.7 1.0 3e-45 154.5 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 CEP10989.1 - 0.2 11.8 2.8 0.33 11.1 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function Dynamin_N PF00350.23 CEP10990.1 - 1.8e-45 155.0 2.6 5.6e-45 153.4 0.0 3.0 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 CEP10990.1 - 2.3e-17 63.1 8.8 9.8e-16 57.8 0.0 3.6 3 1 1 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.23 CEP10990.1 - 2.3e-06 27.7 0.1 3.1e-05 24.0 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CEP10990.1 - 0.002 18.0 0.3 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ComJ PF11033.8 CEP10990.1 - 0.035 13.8 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Competence protein J (ComJ) SMC_N PF02463.19 CEP10990.1 - 0.14 11.6 2.3 4.4 6.7 0.2 3.0 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain Afi1 PF07792.12 CEP10990.1 - 1.7 9.1 6.0 3.2 8.2 0.3 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ABC_tran PF00005.27 CEP10990.1 - 3.6 8.1 5.7 5 7.6 0.0 3.5 4 1 0 4 4 4 0 ABC transporter HLH PF00010.26 CEP10991.1 - 1.2e-07 31.6 1.7 3.4e-07 30.1 1.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CK_II_beta PF01214.18 CEP10992.1 - 7.2e-73 244.3 0.0 8.8e-73 244.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit MMS19_C PF12460.8 CEP10993.1 - 6.8e-100 335.1 10.5 6.8e-100 335.1 10.5 3.7 5 1 0 5 5 5 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CEP10993.1 - 4.7e-90 301.7 5.6 2.2e-89 299.5 0.0 4.2 5 2 0 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 CEP10993.1 - 0.00033 21.1 6.0 0.0014 19.1 0.3 4.2 3 1 1 4 4 4 1 HEAT-like repeat ParcG PF10274.9 CEP10993.1 - 0.075 13.1 0.8 0.33 11.1 0.2 2.5 2 0 0 2 2 2 0 Parkin co-regulated protein HEAT PF02985.22 CEP10993.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat DUF1688 PF07958.11 CEP10994.1 - 9.9e-151 502.2 0.0 1.1e-150 502.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) bZIP_1 PF00170.21 CEP10995.1 - 9.4e-11 41.7 11.1 9.4e-11 41.7 11.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP10995.1 - 0.00014 21.8 5.6 0.00014 21.8 5.6 2.8 3 0 0 3 3 3 1 Basic region leucine zipper CCDC85 PF10226.9 CEP10995.1 - 0.00055 19.7 0.5 0.00055 19.7 0.5 2.2 2 0 0 2 2 2 1 CCDC85 family DUF1993 PF09351.10 CEP10995.1 - 0.25 11.5 3.6 0.22 11.7 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) ACCA PF03255.14 CEP10995.1 - 1.1 9.1 8.3 0.085 12.7 2.8 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Dsh_C PF12316.8 CEP10995.1 - 3.7 7.9 17.7 0.88 9.9 9.0 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4407 PF14362.6 CEP10995.1 - 4.4 6.6 11.8 8 5.7 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRELI PF04707.14 CEP10996.1 - 1.2e-45 155.1 0.2 1.5e-45 154.8 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family eIF3g PF12353.8 CEP10998.1 - 0.018 15.4 0.2 0.029 14.8 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Anti-TRAP PF15777.5 CEP10998.1 - 0.06 13.3 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein CcmH PF03918.14 CEP10998.1 - 0.12 11.6 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Ogr_Delta PF04606.12 CEP10998.1 - 0.61 10.1 3.4 1.2 9.2 2.7 1.9 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger HA2 PF04408.23 CEP11000.1 - 1.8e-21 76.4 0.0 1.8e-21 76.4 0.0 3.8 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP11000.1 - 2.3e-14 53.7 0.2 1e-13 51.6 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEP11000.1 - 4.9e-13 49.2 0.0 1.3e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CEP11000.1 - 4.9e-07 29.7 0.1 1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP11000.1 - 1.1e-06 28.9 0.1 3.1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP11000.1 - 4.1e-05 23.4 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP11000.1 - 0.00019 21.8 0.1 0.00044 20.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP11000.1 - 0.0022 17.3 0.1 0.0096 15.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 CEP11000.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 CEP11000.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CEP11000.1 - 0.02 15.4 0.7 0.17 12.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CEP11000.1 - 0.024 14.7 0.1 0.19 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP11000.1 - 0.026 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CEP11000.1 - 0.026 14.7 0.0 0.17 12.0 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEP11000.1 - 0.035 14.5 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 CEP11000.1 - 0.036 13.7 0.3 0.1 12.2 0.3 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CEP11000.1 - 0.073 12.3 0.5 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 CEP11000.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CEP11000.1 - 0.29 10.4 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 1 0 KaiC Pkinase PF00069.25 CEP11001.1 - 2.8e-50 171.2 0.1 3.7e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11001.1 - 2.1e-28 99.3 0.0 3.1e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP11001.1 - 3.7e-07 29.7 0.0 2.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 CEP11001.1 - 0.0058 15.7 0.2 0.0091 15.0 0.2 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PIP49_C PF12260.8 CEP11001.1 - 0.029 14.0 0.1 0.029 14.0 0.1 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Kdo PF06293.14 CEP11001.1 - 0.07 12.5 0.5 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GFO_IDH_MocA PF01408.22 CEP11001.1 - 0.13 13.1 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NUDIX PF00293.28 CEP11002.1 - 1.3e-10 41.5 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 CEP11002.1 - 0.0032 17.1 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase EMG1 PF03587.14 CEP11003.1 - 2.3e-48 164.5 0.0 3e-35 121.6 0.0 2.0 1 1 1 2 2 2 2 EMG1/NEP1 methyltransferase Peptidase_M16_C PF05193.21 CEP11004.1 - 1.3e-48 165.4 0.0 2.2e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEP11004.1 - 1.5e-41 141.8 0.0 8e-41 139.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Gal4_dimer PF03902.13 CEP11004.1 - 0.029 14.5 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain TRPM_tetra PF16519.5 CEP11004.1 - 0.1 12.7 1.0 0.57 10.3 0.5 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF2564 PF10819.8 CEP11004.1 - 0.24 11.8 2.3 1.2 9.6 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Ribul_P_3_epim PF00834.19 CEP11006.1 - 6e-58 195.5 0.0 1.1e-54 184.9 0.0 2.1 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 CEP11006.1 - 0.0042 16.9 0.0 0.0085 15.9 0.0 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PucR PF07905.11 CEP11006.1 - 0.021 15.1 0.1 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family OMPdecase PF00215.24 CEP11006.1 - 0.049 13.2 0.1 0.095 12.3 0.1 1.4 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family AMPK1_CBM PF16561.5 CEP11007.1 - 3.2e-33 113.8 0.1 8.2e-33 112.5 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CEP11007.1 - 1.7e-26 92.3 4.1 1.7e-26 92.3 4.1 2.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 CEP11007.1 - 0.0073 16.9 0.2 0.029 15.0 0.0 2.1 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) GLTP PF08718.11 CEP11008.1 - 1.3e-45 155.4 0.1 2e-45 154.7 0.1 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Mg_trans_NIPA PF05653.14 CEP11009.1 - 4.2e-24 85.2 13.4 1.4e-13 50.7 3.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CEP11009.1 - 0.00019 21.6 7.8 0.00019 21.6 7.8 3.2 3 1 0 3 3 3 1 EamA-like transporter family Glyco_hydro_38N PF01074.22 CEP11010.1 - 1.3e-82 277.4 0.2 2.3e-82 276.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CEP11010.1 - 1.1e-53 182.5 0.0 1.7e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CEP11010.1 - 3.1e-22 78.5 0.0 1.7e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CEP11010.1 - 5.2e-12 45.7 0.1 1.6e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 CEP11010.1 - 3.3e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3603 PF12227.8 CEP11010.1 - 0.029 13.7 0.5 0.058 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) CbiG_mid PF11761.8 CEP11011.1 - 0.047 13.8 0.0 0.67 10.1 0.0 2.1 1 1 0 1 1 1 0 Cobalamin biosynthesis central region CUE PF02845.16 CEP11012.1 - 6.2e-09 35.4 0.0 1.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 CEP11012.1 - 0.0044 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 SPRY PF00622.28 CEP11013.1 - 5.5e-11 42.6 0.2 8.9e-10 38.7 0.1 2.5 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_3 PF13920.6 CEP11013.1 - 3.2e-10 39.7 1.6 5.9e-10 38.9 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP11013.1 - 0.0003 20.6 3.8 0.00063 19.5 3.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEP11013.1 - 0.0025 17.6 2.9 0.011 15.6 2.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP11013.1 - 0.028 14.8 4.5 0.068 13.5 4.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CEP11013.1 - 0.42 10.6 3.2 0.87 9.6 3.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP11013.1 - 0.61 10.0 5.5 2.1 8.3 5.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 CEP11013.1 - 1.4 7.4 13.4 0.24 9.9 7.7 2.0 2 0 0 2 2 2 0 Macoilin family DMAP_binding PF06464.11 CEP11013.1 - 6.4 7.6 11.9 1.5 9.7 4.6 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain zf-LYAR PF08790.11 CEP11014.1 - 1.8e-14 53.3 5.7 4.1e-14 52.2 5.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CEP11014.1 - 0.00067 19.2 0.2 0.68 9.6 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Arc_trans_TRASH PF08394.10 CEP11014.1 - 0.27 11.6 3.7 1.2 9.5 3.7 2.1 1 0 0 1 1 1 0 Archaeal TRASH domain BBS2_Mid PF14783.6 CEP11015.1 - 2.6e-07 30.6 0.4 0.015 15.3 0.0 4.0 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 CEP11015.1 - 5.3e-07 30.1 0.4 0.00027 21.4 0.0 2.7 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 CEP11015.1 - 1.8e-05 24.0 0.6 0.0024 17.0 0.1 3.2 3 1 0 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 CEP11015.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.1 4 0 0 4 4 4 0 FG-GAP repeat PHTB1_N PF14727.6 CEP11015.1 - 0.064 12.6 0.0 1.9 7.7 0.0 2.7 2 2 0 3 3 3 0 PTHB1 N-terminus WD40_like PF17005.5 CEP11015.1 - 0.072 12.4 0.1 1.5 8.1 0.1 2.6 1 1 0 1 1 1 0 WD40-like domain F-box-like PF12937.7 CEP11016.1 - 9.6e-09 35.0 0.4 2.6e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP11016.1 - 1.4e-07 31.2 0.2 1.4e-07 31.2 0.2 2.1 2 0 0 2 2 2 1 F-box domain DUF3760 PF12586.8 CEP11016.1 - 0.014 15.6 0.4 0.06 13.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) LRR_4 PF12799.7 CEP11016.1 - 0.46 11.0 9.9 19 5.9 0.3 5.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) APOBEC_N PF08210.11 CEP11018.1 - 0.02 14.8 0.6 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 APOBEC-like N-terminal domain ERp29 PF07749.12 CEP11018.1 - 0.092 13.6 1.8 0.44 11.5 0.0 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Mrr_N PF14338.6 CEP11018.1 - 0.21 11.7 1.9 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 Mrr N-terminal domain NDC10_II PF16787.5 CEP11019.1 - 8.8e-23 80.8 0.5 2e-20 73.1 0.6 2.2 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF3463 PF11946.8 CEP11020.1 - 0.0067 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3463) IFN-gamma PF00714.17 CEP11020.1 - 0.028 14.3 0.2 0.051 13.4 0.2 1.4 1 0 0 1 1 1 0 Interferon gamma APS_kinase PF01583.20 CEP11021.1 - 2.4e-71 238.8 0.0 2.9e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CEP11021.1 - 7.1e-08 32.7 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP11021.1 - 0.0017 18.9 0.0 0.0023 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEP11021.1 - 0.0021 17.5 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 CEP11021.1 - 0.0074 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEP11021.1 - 0.05 12.9 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CEP11021.1 - 0.14 12.6 0.1 0.15 12.4 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 CEP11021.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 6PF2K PF01591.18 CEP11021.1 - 0.15 11.3 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 6-phosphofructo-2-kinase 4HBT PF03061.22 CEP11022.1 - 9.7e-12 45.1 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CEP11022.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Usg PF06233.12 CEP11022.1 - 0.064 13.4 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 Usg-like family 4HBT_3 PF13622.6 CEP11022.1 - 0.13 12.5 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily HMG_box PF00505.19 CEP11023.1 - 2.4e-17 63.1 0.1 7e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP11023.1 - 5.4e-11 42.9 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain ZapB PF06005.12 CEP11023.1 - 0.014 15.8 1.0 0.014 15.8 1.0 2.2 3 1 0 3 3 3 0 Cell division protein ZapB Phage_GP20 PF06810.11 CEP11023.1 - 0.078 12.8 2.3 0.17 11.7 0.5 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 bZIP_2 PF07716.15 CEP11023.1 - 0.084 13.0 2.9 0.13 12.3 1.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper CS PF04969.16 CEP11024.1 - 7.2e-07 30.1 1.1 8.1e-07 30.0 0.3 1.5 2 0 0 2 2 2 1 CS domain Glyco_hydro2_C5 PF18565.1 CEP11024.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 DUF2095 PF09868.9 CEP11025.1 - 0.0067 16.4 0.1 0.008 16.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2095) GMC_oxred_N PF00732.19 CEP11026.1 - 1.7e-58 198.4 0.0 2.6e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEP11026.1 - 2e-28 99.7 0.1 3.7e-28 98.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEP11026.1 - 6.7e-07 28.7 0.2 0.00028 20.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CEP11026.1 - 8.3e-06 25.2 0.5 0.00028 20.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP11026.1 - 3.9e-05 23.8 0.1 0.00012 22.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP11026.1 - 4.5e-05 23.2 0.1 0.00025 20.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP11026.1 - 5.7e-05 22.5 1.8 0.033 13.4 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEP11026.1 - 0.00012 21.2 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CEP11026.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CEP11026.1 - 0.051 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 CEP11026.1 - 0.057 12.1 0.3 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Urotensin_II PF02083.15 CEP11027.1 - 0.85 9.4 3.0 2.2 8.2 3.0 1.7 1 0 0 1 1 1 0 Urotensin II PHD PF00628.29 CEP11028.1 - 9.4e-11 41.4 8.1 2.5e-10 40.1 8.1 1.8 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 CEP11028.1 - 3.8e-06 26.9 3.8 3.8e-06 26.9 3.8 3.0 2 1 1 3 3 3 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.6 CEP11028.1 - 0.027 14.0 2.0 0.027 14.0 2.0 2.0 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 CEP11028.1 - 0.57 10.6 6.9 0.31 11.4 4.2 2.0 1 1 0 1 1 1 0 Ring finger domain Ribosomal_60s PF00428.19 CEP11029.1 - 5.9e-25 87.7 5.3 7.2e-25 87.4 5.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CRAL_TRIO PF00650.20 CEP11030.1 - 8.1e-34 116.6 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CEP11030.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP11030.1 - 0.01 16.0 0.6 0.02 15.1 0.6 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain DUF3543 PF12063.8 CEP11030.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Taxilin PF09728.9 CEP11033.1 - 0.019 14.2 0.3 0.026 13.7 0.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein T3SSipB PF16535.5 CEP11033.1 - 0.027 15.0 0.2 0.05 14.1 0.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 CEP11033.1 - 0.035 14.1 0.3 0.057 13.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Retinal PF15449.6 CEP11033.1 - 2.2 6.0 6.8 2.7 5.7 6.8 1.0 1 0 0 1 1 1 0 Retinal protein AbiEi_1 PF09407.10 CEP11035.1 - 0.0059 16.9 0.0 0.0089 16.3 0.0 1.3 1 0 0 1 1 1 1 AbiEi antitoxin C-terminal domain Taxilin PF09728.9 CEP11035.1 - 0.0085 15.3 0.6 0.01 15.1 0.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TSR PF18487.1 CEP11036.1 - 0.016 15.4 6.7 0.016 15.4 6.7 2.0 2 0 0 2 2 2 0 Thrombospondin type 1 repeat Transposase_21 PF02992.14 CEP11036.1 - 0.074 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Transposase family tnp2 zf-CCHC PF00098.23 CEP11038.1 - 0.015 15.4 12.8 0.17 12.0 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP11038.1 - 0.02 14.6 4.1 0.02 14.6 4.1 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP11038.1 - 2.2 8.2 17.7 1.5 8.7 7.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP11038.1 - 5.7 6.8 7.1 5.1 6.9 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle HSR PF03172.13 CEP11040.1 - 0.057 13.6 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 HSR domain Fox-1_C PF12414.8 CEP11040.1 - 0.086 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal zf-RVT PF13966.6 CEP11041.1 - 6.2e-09 36.5 0.1 1.7e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP11041.1 - 1.1e-05 25.1 1.0 4.8e-05 23.0 1.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CEP11043.1 - 0.035 14.8 0.1 0.08 13.7 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP11044.1 - 2.9e-27 95.6 0.1 4e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF190 PF02641.15 CEP11044.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized ACR, COG1993 Snf7 PF03357.21 CEP11046.1 - 1e-43 148.9 25.1 1e-43 148.9 25.1 1.5 2 0 0 2 2 2 1 Snf7 Resolvase PF00239.21 CEP11046.1 - 0.36 10.9 7.6 0.16 12.1 1.7 2.3 1 1 1 2 2 2 0 Resolvase, N terminal domain Peptidase_M2 PF01401.18 CEP11046.1 - 0.71 8.4 6.5 0.88 8.1 6.5 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme HECT PF00632.25 CEP11047.1 - 8.1e-91 304.7 0.6 2.7e-90 303.0 0.2 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CEP11047.1 - 0.033 14.0 0.6 0.12 12.3 0.6 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif YitT_membrane PF02588.15 CEP11047.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 PhoLip_ATPase_C PF16212.5 CEP11048.1 - 1e-43 149.9 11.5 1e-43 149.9 11.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP11048.1 - 3.6e-18 65.0 2.5 9.3e-18 63.7 2.5 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CEP11048.1 - 2.1e-14 53.4 0.0 6.7e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEP11048.1 - 3.5e-12 47.1 2.0 1.3e-05 25.6 2.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP11048.1 - 1.2e-09 38.2 0.0 2.5e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP11048.1 - 0.00055 19.7 0.1 0.003 17.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CwfJ_C_2 PF04676.14 CEP11049.1 - 4.5e-34 117.3 1.8 1.1e-33 116.1 0.7 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CEP11049.1 - 5.4e-33 113.5 0.0 9.5e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-NOSIP PF15906.5 CEP11050.1 - 7e-14 51.7 1.4 1.8e-13 50.4 1.4 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 CEP11050.1 - 1.4e-08 34.4 22.0 8.1e-06 25.6 8.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP11050.1 - 3.6e-07 30.1 15.0 5.8e-05 23.0 5.7 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 CEP11050.1 - 1.2e-06 28.7 19.6 2.6e-06 27.6 7.5 2.5 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.12 CEP11050.1 - 1.4e-06 27.9 4.3 1.4e-06 27.9 4.3 2.7 2 1 1 3 3 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 CEP11050.1 - 3.2e-06 27.0 9.0 3.2e-06 27.0 9.0 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP11050.1 - 0.00031 20.5 22.1 0.00036 20.3 8.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP11050.1 - 0.002 18.0 23.6 0.0035 17.2 9.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP11050.1 - 0.0024 17.7 25.0 0.0034 17.2 5.9 3.9 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEP11050.1 - 0.0042 17.2 19.6 0.014 15.5 7.3 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Asp-B-Hydro_N PF05279.11 CEP11050.1 - 0.41 10.7 10.1 0.56 10.2 10.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-RING_10 PF16685.5 CEP11050.1 - 1.2 9.4 16.1 0.27 11.4 6.8 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1943 PF09172.11 CEP11050.1 - 1.4 8.1 5.9 2.1 7.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) FYVE PF01363.21 CEP11050.1 - 7.3 6.8 20.2 0.73 10.0 8.6 3.1 2 2 0 2 2 2 0 FYVE zinc finger Presenilin PF01080.17 CEP11050.1 - 7.3 5.2 6.3 9.9 4.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 CEP11051.1 - 5.6e-13 48.6 28.6 4.1e-05 23.8 4.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP11051.1 - 2.9e-11 43.2 27.9 1.8e-06 28.1 1.0 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP11051.1 - 8.7e-09 35.5 24.3 0.0021 18.7 3.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP11051.1 - 4.8e-05 23.3 16.8 0.024 14.6 0.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Spt20 PF12090.8 CEP11051.1 - 0.014 15.0 17.5 0.014 15.0 17.5 3.8 3 1 0 3 3 2 0 Spt20 family SOGA PF11365.8 CEP11051.1 - 0.085 14.0 0.7 0.085 14.0 0.7 2.7 2 0 0 2 2 2 0 Protein SOGA Zn-ribbon_8 PF09723.10 CEP11051.1 - 0.15 12.2 9.0 3.4 7.9 0.2 3.1 2 1 1 3 3 3 0 Zinc ribbon domain OmpH PF03938.14 CEP11051.1 - 0.23 11.8 20.3 0.83 10.0 12.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 CEP11051.1 - 0.49 11.3 14.5 0.26 12.2 0.9 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DIRP PF06584.13 CEP11051.1 - 3.1 8.0 8.0 4.5 7.5 0.4 2.4 2 0 0 2 2 2 0 DIRP DUF4407 PF14362.6 CEP11051.1 - 3.6 6.9 9.7 3.6 6.9 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LCD1 PF09798.9 CEP11051.1 - 6 5.3 17.6 0.41 9.1 3.6 2.1 2 0 0 2 2 2 0 DNA damage checkpoint protein Phage_GP20 PF06810.11 CEP11051.1 - 8.9 6.1 13.4 0.15 11.9 2.5 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 PSCyt3 PF07627.11 CEP11051.1 - 9.3 6.6 19.3 0.96 9.8 1.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) KilA-N PF04383.13 CEP11052.1 - 0.00038 20.3 0.0 0.0027 17.5 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain DLIC PF05783.11 CEP11053.1 - 2.9e-70 237.4 17.9 2.8e-54 184.7 0.1 5.0 2 1 2 4 4 4 4 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CEP11053.1 - 0.013 15.9 0.0 0.035 14.5 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CEP11053.1 - 0.014 15.1 0.2 0.035 13.9 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CEP11053.1 - 0.026 15.0 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CEP11053.1 - 0.038 14.5 0.0 0.13 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 CEP11053.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Roc PF08477.13 CEP11053.1 - 0.069 13.4 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CEP11053.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CEP11053.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3720 PF12517.8 CEP11053.1 - 0.66 10.9 10.7 0.39 11.7 6.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) SelK_SelG PF10961.8 CEP11053.1 - 1.5 9.5 8.8 2.2 8.9 0.2 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG 2-Hacid_dh_C PF02826.19 CEP11054.1 - 3.8e-55 186.0 0.0 5.4e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEP11054.1 - 1.8e-20 73.0 0.0 2.1e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 CEP11054.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cyclin_N PF00134.23 CEP11055.1 - 4.2e-11 42.7 0.7 1.2e-09 37.9 0.1 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEP11055.1 - 0.00015 21.8 0.1 0.0004 20.4 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 CEP11055.1 - 0.0055 16.7 0.3 4.8 7.3 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat DUF2497 PF10691.9 CEP11055.1 - 0.031 14.7 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) IDO PF01231.18 CEP11056.1 - 7.7e-148 492.9 0.0 5.9e-138 460.3 0.0 2.1 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 CEP11056.1 - 0.13 10.9 0.5 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) HSP70 PF00012.20 CEP11059.1 - 7.6e-05 21.1 0.2 9.9e-05 20.7 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein SrfB PF07520.11 CEP11059.1 - 0.085 10.7 0.2 0.17 9.7 0.2 1.5 1 1 0 1 1 1 0 Virulence factor SrfB DUF2278 PF10042.9 CEP11059.1 - 0.095 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) GCR1_C PF12550.8 CEP11061.1 - 3.4e-15 56.1 0.8 5.1e-15 55.5 0.8 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes 3-dmu-9_3-mt PF06983.13 CEP11061.1 - 0.081 13.5 0.0 2.5 8.7 0.1 2.1 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase NDC10_II PF16787.5 CEP11062.1 - 3e-48 164.5 0.0 3.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Aminotran_4 PF01063.19 CEP11063.1 - 7.8e-21 75.0 0.0 1.1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV RSN1_7TM PF02714.15 CEP11064.1 - 1.5e-69 234.4 32.9 2.8e-69 233.5 32.9 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP11064.1 - 1.6e-33 116.4 0.0 3.3e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEP11064.1 - 9.2e-21 74.2 8.9 4.5e-20 72.0 0.5 3.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3343 PF11823.8 CEP11064.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) IMUP PF15761.5 CEP11064.1 - 3.1 8.5 6.4 6.8 7.4 6.4 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Com_YlbF PF06133.11 CEP11064.1 - 6.2 7.5 9.5 0.15 12.7 0.2 3.0 4 0 0 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA SLD5_C PF16922.5 CEP11065.1 - 8.3e-09 35.5 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CEP11065.1 - 1.3e-05 25.6 1.1 2.6e-05 24.7 1.1 1.5 1 0 0 1 1 1 1 GINS complex protein MtlR PF05068.12 CEP11065.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Mannitol repressor Presenilin PF01080.17 CEP11066.1 - 8.3 5.1 5.3 7.8 5.1 5.3 1.0 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CEP11067.1 - 3.4e-53 180.7 0.0 5.3e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11067.1 - 3.2e-36 125.0 0.0 4.7e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP11067.1 - 6.2e-06 25.2 0.1 0.00016 20.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEP11067.1 - 4e-05 23.1 0.0 7.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CEP11067.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BAR PF03114.18 CEP11068.1 - 4.8e-32 111.5 6.9 7.1e-32 111.0 6.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CEP11068.1 - 5.1e-16 58.0 0.1 9.3e-16 57.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP11068.1 - 2.2e-13 49.9 0.1 3.7e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP11068.1 - 5.2e-10 38.9 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA PF00004.29 CEP11069.1 - 1e-12 48.6 0.2 3.4e-05 24.3 0.0 2.2 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEP11069.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gar1 PF04410.14 CEP11070.1 - 1.6e-40 138.4 3.8 1.6e-40 138.4 3.8 2.7 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region GDP_Man_Dehyd PF16363.5 CEP11071.1 - 8.5e-161 534.9 0.0 1.4e-160 534.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP11071.1 - 1.3e-73 247.4 0.0 3.3e-73 246.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CEP11071.1 - 3.3e-07 29.7 0.0 5.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CEP11071.1 - 0.0007 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 CEP11071.1 - 0.00088 18.5 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PAS_11 PF14598.6 CEP11071.1 - 0.1 12.7 0.2 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 PAS domain Abhydrolase_6 PF12697.7 CEP11072.1 - 1.9e-20 74.4 0.0 2.6e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEP11072.1 - 1.3e-14 54.5 0.2 8.2e-11 42.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP11072.1 - 5.8e-11 42.1 0.0 7.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CEP11072.1 - 5.7e-06 26.6 0.0 1.2e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 CEP11072.1 - 2.5e-05 23.3 0.1 3.3e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF676 PF05057.14 CEP11072.1 - 0.00037 20.1 0.6 0.00058 19.4 0.6 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CEP11072.1 - 0.00052 19.8 1.5 0.0012 18.6 0.9 1.8 1 1 1 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 CEP11072.1 - 0.0011 18.6 0.3 0.0016 18.0 0.3 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 CEP11072.1 - 0.0064 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CEP11072.1 - 0.0094 15.8 0.0 0.05 13.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Methyltransf_32 PF13679.6 CEP11072.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Esterase PF00756.20 CEP11072.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 CEP11072.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 CEP11072.1 - 0.054 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAF-AH_p_II PF03403.13 CEP11072.1 - 0.078 11.5 0.7 0.09 11.3 0.4 1.5 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF1057 PF06342.12 CEP11072.1 - 0.078 12.0 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2974 PF11187.8 CEP11072.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 CEP11072.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Cutinase DLH PF01738.18 CEP11072.1 - 0.15 11.6 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 CEP11072.1 - 0.18 11.0 0.5 0.42 9.7 0.1 1.6 1 1 1 2 2 2 0 Lecithin:cholesterol acyltransferase TssO PF17561.2 CEP11073.1 - 0.07 13.2 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Mito_carr PF00153.27 CEP11074.1 - 1e-66 220.9 2.8 3.1e-22 78.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.18 CEP11075.1 - 1.1e-48 163.2 4.1 1.7e-48 162.6 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Acyltransferase PF01553.21 CEP11076.1 - 4.6e-14 52.2 0.0 7.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NIF PF03031.18 CEP11077.1 - 1.4e-23 83.4 0.0 2.7e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 CEP11077.1 - 5.4e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CEP11077.1 - 2.6e-05 24.5 0.0 8.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CEP11077.1 - 0.00083 19.6 0.2 0.0032 17.7 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain HHH_8 PF14716.6 CEP11077.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain AA_permease PF00324.21 CEP11078.1 - 3.5e-128 428.2 58.4 4.1e-128 428.0 58.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP11078.1 - 9.4e-39 133.4 62.1 1.3e-38 132.9 62.1 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 CEP11079.1 - 6.9e-55 186.3 0.0 1.1e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11079.1 - 2.7e-25 89.1 0.0 5.1e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CEP11079.1 - 3.8e-19 68.6 3.2 1.9e-10 40.8 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Haspin_kinase PF12330.8 CEP11079.1 - 0.025 13.5 3.2 0.46 9.4 0.3 3.2 3 1 0 3 3 3 0 Haspin like kinase domain SnAC PF14619.6 CEP11079.1 - 0.047 14.3 1.1 8.5 7.1 0.4 3.5 2 1 1 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Ank_2 PF12796.7 CEP11080.1 - 1.8e-55 185.4 14.7 4.2e-13 49.7 0.0 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Abhydrolase_3 PF07859.13 CEP11080.1 - 4.1e-46 157.5 0.0 7.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_4 PF13637.6 CEP11080.1 - 1.8e-31 108.1 7.0 9e-08 32.5 0.0 7.8 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP11080.1 - 6.9e-27 93.2 2.0 6e-09 36.0 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP11080.1 - 7.6e-24 81.2 6.2 0.00027 21.1 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 CEP11080.1 - 2.7e-19 68.7 7.9 0.0043 17.4 0.0 8.2 8 1 0 8 8 8 4 Ankyrin repeat Say1_Mug180 PF10340.9 CEP11080.1 - 3.5e-15 55.7 0.1 6.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CEP11080.1 - 0.035 13.4 0.0 0.086 12.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 CEP11080.1 - 0.11 11.3 0.0 0.37 9.6 0.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family TMEM173 PF15009.6 CEP11080.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 173 Dfp1_Him1_M PF08630.10 CEP11081.1 - 3e-21 76.0 0.1 3e-21 76.0 0.1 3.1 3 1 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 CEP11081.1 - 5.3e-15 55.2 1.7 1.3e-14 54.0 1.7 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 CEP11081.1 - 0.0014 18.9 0.1 0.0043 17.4 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CEP11081.1 - 0.0035 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF1284 PF06935.11 CEP11081.1 - 0.0066 16.9 0.3 0.019 15.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1284) CAP59_mtransfer PF11735.8 CEP11081.1 - 0.2 11.3 2.3 1.4 8.6 1.9 2.2 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 NIF PF03031.18 CEP11082.1 - 2.7e-25 89.0 0.7 4.5e-25 88.2 0.2 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Acyl-CoA_dh_1 PF00441.24 CEP11083.1 - 2.2e-32 112.4 0.3 3.2e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CEP11083.1 - 3.3e-19 68.8 0.0 7.9e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CEP11083.1 - 3.5e-19 68.8 0.1 6.3e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEP11083.1 - 2.6e-12 47.4 0.0 5.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP11083.1 - 6e-09 36.3 0.0 1.1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mso1_Sec1_bdg PF14475.6 CEP11084.1 - 4.1e-05 23.1 0.2 4.1e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 Sec1-binding region of Mso1 zf-C2H2_4 PF13894.6 CEP11085.1 - 0.048 14.5 0.3 0.14 13.1 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CEP11085.1 - 0.056 13.3 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 CEP11085.1 - 0.057 13.7 1.9 0.057 13.7 1.9 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CEP11085.1 - 0.26 11.9 7.5 0.16 12.6 1.9 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HNH_5 PF14279.6 CEP11086.1 - 0.0092 15.8 5.5 0.014 15.2 0.0 3.0 2 1 1 3 3 3 1 HNH endonuclease HNH PF01844.23 CEP11086.1 - 0.37 11.0 5.0 0.45 10.7 0.0 3.1 3 0 0 3 3 3 0 HNH endonuclease NMD3 PF04981.13 CEP11087.1 - 0.013 15.0 2.3 0.024 14.1 0.0 2.1 2 1 0 2 2 2 0 NMD3 family DUF1272 PF06906.11 CEP11087.1 - 0.073 13.2 5.4 0.11 12.6 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 CEP11087.1 - 2.9 8.0 7.9 2.3 8.3 2.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon NinF PF05810.12 CEP11087.1 - 5.6 6.9 6.0 10 6.1 0.3 3.0 2 1 1 3 3 3 0 NinF protein peroxidase PF00141.23 CEP11088.1 - 1.2e-43 149.4 0.0 1.8e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF5039 PF16442.5 CEP11089.1 - 0.0041 16.7 0.5 0.012 15.2 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5039) TTL PF03133.15 CEP11090.1 - 8.9e-57 192.4 3.6 2.6e-56 190.9 3.6 1.7 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family APOBEC_C PF05240.14 CEP11090.1 - 0.11 12.5 1.0 0.31 11.0 1.0 1.8 1 0 0 1 1 1 0 APOBEC-like C-terminal domain EFhand_Ca_insen PF08726.10 CEP11090.1 - 2.4 8.3 6.1 31 4.8 0.2 3.7 3 0 0 3 3 3 0 Ca2+ insensitive EF hand TPR_12 PF13424.6 CEP11091.1 - 1.2e-07 31.9 5.4 1.7e-06 28.2 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat FAR1 PF03101.15 CEP11091.1 - 2.1e-07 31.6 1.4 4.9e-07 30.4 1.4 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain SHNi-TPR PF10516.9 CEP11091.1 - 4.5e-07 29.2 4.5 1.3e-05 24.6 0.0 3.7 4 1 0 4 4 4 1 SHNi-TPR Tub_N PF16322.5 CEP11091.1 - 0.0012 19.3 2.6 0.0012 19.3 2.6 2.3 2 1 0 2 2 2 1 Tubby N-terminal TPR_1 PF00515.28 CEP11091.1 - 0.0042 16.8 6.5 0.032 14.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP11091.1 - 0.01 15.7 1.5 0.12 12.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11091.1 - 0.024 14.3 14.6 2.3 8.0 0.4 5.8 4 2 1 5 5 5 0 TPR repeat TPR_2 PF07719.17 CEP11091.1 - 0.033 14.3 8.8 2.4 8.5 0.1 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11091.1 - 0.14 12.4 7.3 19 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PRTase_2 PF15609.6 CEP11091.1 - 0.18 11.3 1.7 0.23 11.0 0.2 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase TPR_17 PF13431.6 CEP11091.1 - 0.21 12.0 2.3 4.1 8.0 0.4 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Mer2 PF09074.10 CEP11091.1 - 3.8 7.3 11.4 56 3.5 11.4 2.4 1 1 0 1 1 1 0 Mer2 TPR_16 PF13432.6 CEP11091.1 - 4.2 8.1 7.3 7.3 7.3 0.6 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat DUF1664 PF07889.12 CEP11091.1 - 9.3 6.3 7.0 6.9 6.7 0.9 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Flavokinase PF01687.17 CEP11092.1 - 1.3e-36 125.2 0.0 1.6e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Glyco_hydro_31 PF01055.26 CEP11093.1 - 1.6e-54 185.8 2.2 2.2e-54 185.3 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEP11093.1 - 3e-05 24.3 0.2 0.00026 21.2 0.2 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like Gpr1_Fun34_YaaH PF01184.19 CEP11094.1 - 3.8e-27 95.3 25.8 4.5e-27 95.0 25.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family rve PF00665.26 CEP11095.1 - 0.038 14.2 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain NDC10_II PF16787.5 CEP11098.1 - 5.2e-19 68.4 0.0 5.6e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Anemone_cytotox PF06369.12 CEP11098.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein DUF1091 PF06477.13 CEP11098.1 - 0.065 13.7 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) NDC10_II PF16787.5 CEP11099.1 - 8.4e-09 34.9 0.4 1.3e-08 34.3 0.4 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Sif PF06767.11 CEP11099.1 - 8.5e-06 25.0 0.4 1.1e-05 24.6 0.4 1.1 1 0 0 1 1 1 1 Sif protein Pkinase PF00069.25 CEP11100.1 - 9.5e-44 149.7 0.1 1.2e-43 149.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11100.1 - 2.5e-26 92.5 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP11100.1 - 9.2e-09 35.0 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CEP11100.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP11100.1 - 0.034 13.7 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-RVT PF13966.6 CEP11101.1 - 3.1e-05 24.6 1.8 7.3e-05 23.4 1.8 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Opi1 PF08618.10 CEP11102.1 - 7e-53 180.4 6.8 4.9e-50 171.0 6.8 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 DUF4055 PF13264.6 CEP11102.1 - 0.0028 17.8 0.2 0.0079 16.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4055) Mon1 PF03164.14 CEP11102.1 - 0.035 13.2 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 DSPc PF00782.20 CEP11103.1 - 5e-06 26.4 0.0 1.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Sgf11 PF08209.11 CEP11103.1 - 0.00024 20.6 0.1 0.00024 20.6 0.1 2.3 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) Y_phosphatase PF00102.27 CEP11103.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CEP11103.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Tho2 PF11262.8 CEP11103.1 - 0.037 13.2 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ribosomal_L18 PF17135.4 CEP11103.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Pkinase PF00069.25 CEP11104.1 - 1.4e-36 126.2 0.0 8.7e-21 74.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11104.1 - 1.9e-10 40.5 0.0 4e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase zf-RING_2 PF13639.6 CEP11106.1 - 1.1e-11 44.9 6.9 1.9e-11 44.1 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEP11106.1 - 6.5e-09 35.5 5.8 1.2e-08 34.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP11106.1 - 7.6e-09 35.3 7.0 1.4e-08 34.5 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP11106.1 - 9.1e-08 31.9 3.9 1.5e-07 31.2 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CEP11106.1 - 8.3e-07 28.6 3.6 8.3e-07 28.6 3.6 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEP11106.1 - 9.9e-06 25.3 7.8 1.7e-05 24.6 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP11106.1 - 2.6e-05 24.1 2.0 2.6e-05 24.1 2.0 2.6 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP11106.1 - 2.7e-05 23.9 8.2 5.2e-05 23.0 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP11106.1 - 0.00028 21.1 7.9 0.0018 18.5 7.9 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CEP11106.1 - 0.0038 17.0 6.4 0.0066 16.2 6.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CEP11106.1 - 0.0089 16.2 5.6 0.022 14.9 5.6 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2073 PF09846.9 CEP11106.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) DUF1272 PF06906.11 CEP11106.1 - 0.64 10.1 4.4 1.3 9.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) G_glu_transpept PF01019.21 CEP11108.1 - 1.5e-152 509.0 0.0 1.5e-152 509.0 0.0 2.2 3 0 0 3 3 3 1 Gamma-glutamyltranspeptidase TAF4 PF05236.14 CEP11108.1 - 6.2e-20 72.1 16.3 2.3e-17 63.6 10.2 3.1 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family Vac_ImportDeg PF09783.9 CEP11109.1 - 1.6e-58 197.1 1.3 2e-58 196.8 1.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein SecY PF00344.20 CEP11110.1 - 3e-56 190.9 15.1 4.6e-56 190.3 15.1 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CEP11110.1 - 5.3e-15 55.0 1.1 1.9e-14 53.2 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p Tom22 PF04281.13 CEP11110.1 - 0.04 13.7 7.1 0.074 12.8 6.9 1.6 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.14 CEP11110.1 - 0.045 12.1 3.4 0.059 11.7 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CEP11110.1 - 0.047 11.9 6.2 0.062 11.5 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2076 PF09849.9 CEP11110.1 - 0.053 13.6 3.9 0.071 13.1 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SDA1 PF05285.12 CEP11110.1 - 0.076 12.4 7.2 0.1 12.0 7.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4064 PF13273.6 CEP11110.1 - 0.35 11.2 8.5 2.1 8.7 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) YL1 PF05764.13 CEP11110.1 - 0.37 10.9 4.8 0.53 10.4 4.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 CEP11110.1 - 0.37 10.1 6.8 0.51 9.6 6.8 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 CEP11110.1 - 0.48 10.1 13.7 0.77 9.4 13.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CEP11110.1 - 0.49 8.4 16.6 0.71 7.9 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Roughex PF06020.11 CEP11110.1 - 0.8 8.7 3.1 1.2 8.2 3.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RRN3 PF05327.11 CEP11110.1 - 1.3 7.5 6.9 1.8 7.0 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 CEP11110.1 - 1.9 8.0 11.6 2.9 7.4 11.6 1.2 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 CEP11110.1 - 3.7 7.2 4.8 7.6 6.2 4.8 1.5 1 0 0 1 1 1 0 FAM176 family Sulfate_transp PF00916.20 CEP11112.1 - 7.3e-111 370.6 20.3 9.5e-111 370.2 20.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP11112.1 - 1.6e-11 43.9 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP11112.1 - 8.1e-05 23.0 2.5 8.1e-05 23.0 2.5 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CEP11112.1 - 0.018 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 STAS domain CBM_21 PF03370.13 CEP11113.1 - 5.4e-25 87.8 2.4 1e-24 86.9 2.4 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEP11113.1 - 2.1e-12 47.4 1.3 4.6e-12 46.4 1.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Sec63 PF02889.16 CEP11114.1 - 6.2e-26 91.1 0.7 9.6e-26 90.5 0.7 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CEP11114.1 - 6.5e-22 78.1 0.2 1.7e-21 76.8 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP11114.1 - 3.4e-15 56.4 0.1 7.9e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP11114.1 - 8e-09 35.8 0.0 5.8e-08 33.1 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEP11114.1 - 0.0023 18.2 0.2 0.047 14.0 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP11114.1 - 0.0027 18.0 0.3 0.018 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEP11114.1 - 0.04 13.0 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CEP11114.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain HHH_5 PF14520.6 CEP11114.1 - 0.091 13.4 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1899 PF08953.11 CEP11115.1 - 4.7e-12 45.6 0.0 8.4e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CEP11115.1 - 3.2e-11 43.0 0.1 6.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CEP11115.1 - 5.1e-09 36.6 1.5 0.13 13.2 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11115.1 - 2.2e-07 31.0 0.0 5.6e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP11115.1 - 0.0041 17.0 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CEP11115.1 - 0.076 11.7 0.0 0.27 9.9 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Ge1_WD40 PF16529.5 CEP11115.1 - 0.094 11.7 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 CEP11116.1 - 1.6e-05 24.7 0.0 0.00022 21.0 0.0 2.4 1 1 1 2 2 2 1 F-box-like F-box-like PF12937.7 CEP11117.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like LIP1 PF15904.5 CEP11117.1 - 0.073 13.4 0.1 0.27 11.6 0.1 2.0 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Acetyltransf_1 PF00583.25 CEP11118.1 - 1.1e-12 48.2 0.2 1.4e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP11118.1 - 1.1e-08 35.3 0.2 1.7e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP11118.1 - 3.4e-08 33.5 0.6 4.6e-08 33.0 0.6 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cystatin PF00031.21 CEP11118.1 - 0.18 12.1 1.9 0.44 10.8 0.2 2.0 2 0 0 2 2 2 0 Cystatin domain Abhydro_lipase PF04083.16 CEP11119.1 - 4.8e-19 67.7 1.3 5.9e-19 67.4 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CEP11119.1 - 7.9e-06 25.7 0.2 1.9e-05 24.5 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP11119.1 - 6.6e-05 22.3 0.0 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 CEP11119.1 - 0.045 13.1 0.0 0.24 10.7 0.0 2.1 3 0 0 3 3 3 0 Secretory lipase Abhydrolase_6 PF12697.7 CEP11119.1 - 0.05 14.2 0.0 0.073 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.23 CEP11120.1 - 3e-05 23.7 0.0 6.2e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP11120.1 - 0.021 14.7 0.0 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP11121.1 - 0.064 13.4 12.8 0.36 11.0 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP11121.1 - 0.28 11.0 9.0 0.043 13.5 4.1 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger Sugar_tr PF00083.24 CEP11122.1 - 1.6e-75 254.7 26.5 1.9e-75 254.5 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP11122.1 - 4.9e-16 58.6 35.0 1.3e-15 57.2 30.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.22 CEP11123.1 - 2.2e-14 53.6 3.0 1.6e-07 31.5 0.0 3.3 2 1 1 3 3 3 3 Thioesterase superfamily Tubulin PF00091.25 CEP11124.1 - 2.2e-58 197.7 0.0 3.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP11124.1 - 1.6e-44 151.1 0.3 5.1e-44 149.5 0.1 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain THF_DHG_CYH PF00763.23 CEP11124.1 - 3.2e-24 85.4 0.0 7.6e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CEP11124.1 - 3.1e-12 46.1 0.2 1.9e-10 40.3 0.2 2.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Tubulin_3 PF14881.6 CEP11124.1 - 0.004 16.9 0.1 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 CEP11124.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like bZIP_2 PF07716.15 CEP11125.1 - 2.5e-12 46.6 8.5 4.5e-12 45.9 8.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP11125.1 - 0.0022 18.0 8.1 0.0045 17.1 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 CEP11125.1 - 0.021 14.6 1.8 0.062 13.1 1.8 1.8 1 0 0 1 1 1 0 Septum formation initiator PspB PF06667.12 CEP11125.1 - 0.1 12.7 1.1 0.2 11.7 1.1 1.4 1 0 0 1 1 1 0 Phage shock protein B CLTH PF10607.9 CEP11125.1 - 0.1 12.5 0.4 0.2 11.6 0.4 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF2203 PF09969.9 CEP11125.1 - 0.2 12.4 2.0 0.35 11.6 2.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1192 PF06698.11 CEP11125.1 - 0.28 11.3 4.9 0.12 12.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) EMP24_GP25L PF01105.24 CEP11125.1 - 1 9.3 4.2 0.34 10.8 1.5 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD UPF0014 PF03649.13 CEP11126.1 - 1.1e-55 188.7 14.2 2e-55 187.8 14.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0014) RINGv PF12906.7 CEP11126.1 - 1.4e-09 37.9 5.5 2.7e-09 37.0 5.5 1.5 1 0 0 1 1 1 1 RING-variant domain BPD_transp_1 PF00528.22 CEP11126.1 - 0.00071 19.4 8.0 0.00071 19.4 8.0 1.9 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component zf-RING_2 PF13639.6 CEP11126.1 - 0.22 11.9 8.2 0.53 10.7 8.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-AD PF07776.15 CEP11126.1 - 0.25 11.6 3.1 0.71 10.1 3.1 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C3HC4_3 PF13920.6 CEP11126.1 - 6.7 6.7 7.5 42 4.1 7.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CEP11128.1 - 2.1e-09 37.1 14.4 4.2e-09 36.2 14.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP11128.1 - 0.0029 17.1 9.0 0.005 16.4 9.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CEP11128.1 - 0.034 14.2 5.5 0.091 12.8 5.5 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger RPS31 PF17067.5 CEP11128.1 - 0.16 12.2 0.3 0.16 12.2 0.3 3.3 3 1 1 4 4 4 0 Ribosomal protein S31e eIF3m_C_helix PF18005.1 CEP11129.1 - 1.5e-12 47.0 0.6 3.7e-12 45.7 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 CEP11129.1 - 9e-10 39.0 0.2 2.5e-09 37.6 0.2 1.8 1 0 0 1 1 1 1 PCI domain Sigma70_ECF PF07638.11 CEP11129.1 - 0.066 13.1 0.7 2.9 7.7 0.0 2.9 2 1 1 3 3 3 0 ECF sigma factor ING PF12998.7 CEP11130.1 - 1.3e-11 45.0 5.8 1.3e-11 45.0 5.8 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEP11130.1 - 2.2e-06 27.5 8.1 4.6e-06 26.4 8.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP11130.1 - 0.005 16.4 2.6 0.011 15.3 2.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEP11130.1 - 0.038 14.2 0.5 0.11 12.8 0.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CEP11130.1 - 0.065 13.4 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain CDC45 PF02724.14 CEP11130.1 - 0.24 9.7 6.5 0.31 9.3 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CEP11130.1 - 2.1 6.3 16.0 0.44 8.6 12.0 1.7 2 0 0 2 2 2 0 DNA polymerase phi Merozoite_SPAM PF07133.11 CEP11130.1 - 4.3 7.3 26.6 0.32 11.0 20.4 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) TRAP_alpha PF03896.16 CEP11130.1 - 5.2 6.2 9.2 1.7 7.7 6.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 CEP11130.1 - 7.1 6.9 14.0 0.99 9.7 9.4 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Abhydrolase_1 PF00561.20 CEP11131.1 - 1.9e-27 96.5 0.3 2.2e-24 86.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP11131.1 - 1.5e-18 67.0 0.1 6e-18 65.0 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP11131.1 - 5e-14 53.4 0.0 6.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CEP11131.1 - 1.2e-07 31.8 0.0 5.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.7 CEP11131.1 - 0.00021 21.1 0.1 1.4 8.6 0.0 3.0 2 1 0 2 2 2 2 Alpha/beta hydrolase family Thioesterase PF00975.20 CEP11131.1 - 0.00054 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 CEP11131.1 - 0.017 14.6 0.0 6.9 6.1 0.0 2.5 2 1 1 3 3 3 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CEP11131.1 - 0.066 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 CEP11131.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 CEP11131.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Mating_N PF12731.7 CEP11131.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 FHA PF00498.26 CEP11132.1 - 4.2e-17 62.2 0.0 8.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEP11132.1 - 4.9e-07 30.0 0.0 2.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain T3SS_needle_F PF09392.10 CEP11132.1 - 0.086 13.0 1.8 0.19 11.9 0.7 2.2 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Nop14 PF04147.12 CEP11132.1 - 8.7 4.4 26.0 12 4.0 26.0 1.1 1 0 0 1 1 1 0 Nop14-like family NUDIX PF00293.28 CEP11133.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PSP1 PF04468.12 CEP11134.1 - 3.1e-07 30.6 0.3 3.1e-07 30.6 0.3 2.4 2 1 0 2 2 2 1 PSP1 C-terminal conserved region Activator_LAG-3 PF11498.8 CEP11134.1 - 0.23 10.4 33.3 0.5 9.3 33.3 1.6 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Exonuc_VII_L PF02601.15 CEP11134.1 - 1.2 8.7 14.0 0.063 12.8 8.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit PIEZO PF15917.5 CEP11134.1 - 1.8 8.0 17.1 0.8 9.1 12.4 2.3 2 0 0 2 2 2 0 Piezo Macoilin PF09726.9 CEP11134.1 - 2.1 6.8 21.8 2.9 6.4 21.8 1.2 1 1 0 1 1 1 0 Macoilin family GATA PF00320.27 CEP11135.1 - 3.8e-17 61.6 3.5 8e-17 60.6 3.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CEP11135.1 - 6.8e-14 51.4 0.9 1.6e-13 50.2 0.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 CEP11135.1 - 0.23 11.0 0.6 0.45 10.1 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Arrestin_C PF02752.22 CEP11136.1 - 1.4e-21 77.4 0.0 2.8e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP11136.1 - 1e-09 38.6 0.0 2.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP11136.1 - 0.00042 20.1 0.2 0.0075 16.0 0.1 2.6 2 1 0 2 2 2 1 Arrestin_N terminal like Vps26 PF03643.15 CEP11136.1 - 0.0043 16.1 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.10 CEP11136.1 - 0.019 14.2 0.2 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Rgp1 SUV3_C PF12513.8 CEP11137.1 - 5.8e-16 58.2 2.1 1.2e-15 57.1 0.4 2.5 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 CEP11137.1 - 1.5e-11 44.0 0.6 3.5e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 CEP11137.1 - 1.5e-10 41.4 0.0 3.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_N PF18114.1 CEP11137.1 - 0.0017 18.5 0.3 0.0051 16.9 0.3 1.9 1 0 0 1 1 1 1 Suv3 helical N-terminal domain HSBP1 PF06825.12 CEP11138.1 - 4.9e-08 32.7 0.9 8.3e-08 32.0 0.9 1.4 1 1 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 CEP11138.1 - 2.6e-06 27.2 0.7 5.1e-06 26.2 0.6 1.5 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Fzo_mitofusin PF04799.13 CEP11138.1 - 0.0042 16.7 0.2 0.0045 16.6 0.2 1.1 1 0 0 1 1 1 1 fzo-like conserved region Apolipoprotein PF01442.18 CEP11138.1 - 0.011 15.6 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.20 CEP11138.1 - 0.011 15.7 0.2 0.013 15.5 0.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit CLZ PF16526.5 CEP11138.1 - 0.013 15.8 0.2 0.021 15.2 0.2 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 CEP11138.1 - 0.018 15.5 0.5 0.042 14.3 0.3 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3287 PF11690.8 CEP11138.1 - 0.022 14.5 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Baculo_PEP_C PF04513.12 CEP11138.1 - 0.026 14.6 1.5 0.03 14.4 1.5 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PspB PF06667.12 CEP11138.1 - 0.028 14.5 0.7 0.34 11.0 0.4 2.0 1 1 1 2 2 2 0 Phage shock protein B MazG-like PF12643.7 CEP11138.1 - 0.04 14.2 0.1 0.045 14.0 0.1 1.2 1 0 0 1 1 1 0 MazG-like family DUF1664 PF07889.12 CEP11138.1 - 0.072 13.1 0.2 0.078 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 CEP11138.1 - 0.081 13.0 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Synaptobrevin PF00957.21 CEP11138.1 - 0.081 12.7 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF2452 PF10504.9 CEP11138.1 - 0.12 11.8 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) FAM76 PF16046.5 CEP11138.1 - 0.16 11.3 0.2 0.17 11.2 0.2 1.0 1 0 0 1 1 1 0 FAM76 protein XhlA PF10779.9 CEP11138.1 - 0.43 10.8 2.4 0.87 9.8 0.9 2.0 2 1 1 3 3 3 0 Haemolysin XhlA Peptidase_C65 PF10275.9 CEP11139.1 - 1.9e-66 224.0 0.2 2.2e-66 223.8 0.2 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CEP11139.1 - 7.1e-07 29.8 0.0 6.9e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease CAP_GLY PF01302.25 CEP11141.1 - 7.7e-22 77.1 0.8 1.2e-21 76.4 0.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CEP11141.1 - 0.00064 19.5 1.9 0.0011 18.8 1.9 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle NDK PF00334.19 CEP11142.1 - 1.5e-52 177.2 0.0 2.1e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HSP70 PF00012.20 CEP11143.1 - 3.1e-235 782.0 12.6 3.6e-235 781.8 12.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP11143.1 - 1.3e-17 63.6 2.3 1.2e-16 60.5 1.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEP11143.1 - 0.00071 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.16 CEP11143.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartate decarboxylase eIF3_N PF09440.10 CEP11143.1 - 0.063 13.7 5.6 0.035 14.5 1.9 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Raco_middle PF17651.1 CEP11143.1 - 0.12 12.1 0.2 4.1 7.1 0.0 3.2 2 1 1 3 3 3 0 RACo middle region Homeodomain PF00046.29 CEP11144.1 - 4.9e-16 58.3 1.0 8.7e-16 57.5 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP11144.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 CEP11144.1 - 0.074 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain SH3_2 PF07653.17 CEP11145.1 - 4.2e-06 26.3 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP11145.1 - 5.2e-06 26.0 0.0 9.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP11145.1 - 0.00035 20.4 0.1 0.00063 19.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pyrophosphatase PF00719.19 CEP11146.1 - 8.3e-59 198.0 1.1 8.3e-59 198.0 1.1 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase Ribosomal_S6e PF01092.19 CEP11147.1 - 6.1e-61 203.9 1.3 6.5e-61 203.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e BTB_2 PF02214.22 CEP11148.1 - 0.0015 18.8 1.8 0.017 15.5 0.6 2.8 1 1 1 2 2 2 1 BTB/POZ domain Fumble PF03630.14 CEP11148.1 - 0.014 14.6 0.1 0.023 13.9 0.1 1.4 1 1 0 1 1 1 0 Fumble DUF1977 PF09320.11 CEP11149.1 - 1.3e-27 96.1 2.5 3.1e-27 94.9 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CEP11149.1 - 9.7e-25 86.5 1.0 2.2e-24 85.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CEP11149.1 - 0.017 15.2 0.5 0.17 12.1 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Fibrillarin PF01269.17 CEP11150.1 - 2.8e-108 360.3 0.0 3.5e-108 359.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CEP11150.1 - 4.9e-05 23.1 0.0 7.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CEP11150.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CEP11150.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CEP11150.1 - 0.025 14.2 0.0 0.065 12.9 0.0 1.6 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Rhodanese PF00581.20 CEP11151.1 - 1.7e-23 83.2 0.0 8.2e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain ALMT PF11744.8 CEP11152.1 - 4.1e-20 72.1 7.8 4.1e-20 72.1 7.8 1.7 1 1 1 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 CEP11152.1 - 4e-10 39.9 13.2 7e-10 39.1 13.0 1.6 1 1 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEP11152.1 - 3.6e-07 29.1 6.7 6.5e-07 28.3 6.4 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 CEP11152.1 - 0.087 11.8 11.3 0.6 9.1 1.0 2.5 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal DUF2464 PF10240.9 CEP11152.1 - 0.13 11.8 0.6 0.28 10.7 0.6 1.5 1 0 0 1 1 1 0 Multivesicular body subunit 12 Ribosomal_L7Ae PF01248.26 CEP11153.1 - 7.9e-26 89.6 0.0 9.7e-26 89.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CEP11153.1 - 0.00052 19.9 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CEP11153.1 - 0.0025 17.9 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 FlxA PF14282.6 CEP11153.1 - 0.15 12.1 2.8 0.33 11.0 0.2 2.0 2 0 0 2 2 2 0 FlxA-like protein Rib_5-P_isom_A PF06026.14 CEP11155.1 - 0.064 12.9 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) WD40 PF00400.32 CEP11156.1 - 9e-31 105.5 7.5 3.6e-05 24.5 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat Sof1 PF04158.14 CEP11156.1 - 5.6e-26 90.6 13.6 8.4e-26 90.1 13.6 1.3 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.11 CEP11156.1 - 2e-09 37.6 0.9 4.1e-06 26.8 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CEP11156.1 - 3.3e-05 24.1 0.0 0.087 13.1 0.0 4.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP11156.1 - 0.011 15.1 0.2 3.1 7.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 CEP11156.1 - 0.025 13.5 0.1 0.22 10.5 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PI3K_p85B PF02192.16 CEP11156.1 - 0.16 11.7 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain CUE PF02845.16 CEP11157.1 - 1.4e-10 40.6 0.2 2.8e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 CUE domain RA PF00788.23 CEP11158.1 - 3.3e-12 46.9 0.0 3.7e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CEP11158.1 - 1.1e-07 31.4 0.0 2.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP11158.1 - 0.00067 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP11158.1 - 0.0047 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain TUG-UBL1 PF11470.8 CEP11158.1 - 0.0084 16.3 0.1 1.1 9.6 0.0 3.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain SH3_10 PF17902.1 CEP11158.1 - 0.056 13.5 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 SH3 domain ULD PF16534.5 CEP11158.1 - 0.059 13.4 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like oligomerisation domain of SATB PPR_2 PF13041.6 CEP11159.1 - 2.3e-62 207.0 24.6 1.1e-13 51.2 0.2 12.4 8 4 6 14 14 14 10 PPR repeat family PPR_3 PF13812.6 CEP11159.1 - 3.7e-51 171.1 11.5 2.9e-13 49.7 0.5 9.4 7 2 2 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 CEP11159.1 - 3.8e-41 136.5 18.2 0.00047 20.2 0.0 14.6 16 0 0 16 16 16 8 PPR repeat PPR_1 PF12854.7 CEP11159.1 - 1.2e-36 124.0 17.9 7.4e-05 22.4 0.0 13.5 14 0 0 14 14 14 8 PPR repeat PPR_long PF17177.4 CEP11159.1 - 2.1e-28 99.1 7.5 1.5e-07 31.1 0.2 6.7 1 1 5 6 6 6 5 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CEP11159.1 - 1.2e-07 31.6 5.4 3.3 7.6 0.0 6.2 4 2 2 6 6 6 3 Mitochondrial ATPase expression MNE1 PF13762.6 CEP11159.1 - 6.1e-05 23.0 10.8 0.65 10.0 0.0 5.1 4 2 1 5 5 5 2 Mitochondrial splicing apparatus component TPR_19 PF14559.6 CEP11159.1 - 0.00064 20.2 1.2 1.2 9.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RPM2 PF08579.11 CEP11159.1 - 0.0012 19.2 16.0 6.1 7.3 3.6 6.4 3 3 3 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.17 CEP11159.1 - 0.0074 16.7 2.2 8.6 6.8 0.0 4.3 5 1 0 5 5 5 1 Bacterial transcriptional activator domain PhageMin_Tail PF10145.9 CEP11159.1 - 0.015 15.2 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Phage-related minor tail protein DUF1694 PF07997.11 CEP11159.1 - 0.073 13.2 0.6 0.47 10.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) DUF3430 PF11912.8 CEP11159.1 - 0.13 12.3 2.4 0.15 12.0 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3430) DDE_3 PF13358.6 CEP11160.1 - 7.7e-17 61.4 0.4 1.4e-16 60.6 0.4 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP11160.1 - 1.3e-16 60.6 0.7 2.9e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP11160.1 - 1.8e-07 31.7 1.4 4e-07 30.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP11160.1 - 4e-06 26.8 0.1 6.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP11160.1 - 0.00025 20.9 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 CEP11160.1 - 0.0012 18.4 0.1 0.085 12.4 0.0 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 CEP11160.1 - 0.0012 18.5 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP11160.1 - 0.0015 18.6 1.2 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP11160.1 - 0.0037 17.0 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP11160.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP11160.1 - 0.026 14.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.7 CEP11160.1 - 0.13 12.2 2.1 16 5.6 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Heme_oxygenase PF01126.20 CEP11162.1 - 7.6e-56 189.1 1.8 1e-55 188.7 1.8 1.2 1 0 0 1 1 1 1 Heme oxygenase HsdM_N PF12161.8 CEP11162.1 - 0.017 15.8 1.0 0.039 14.6 0.1 1.9 1 1 1 2 2 2 0 HsdM N-terminal domain BPL_N PF09825.9 CEP11163.1 - 1.6e-116 389.5 0.0 2e-116 389.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CEP11163.1 - 1.2e-22 80.2 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CEP11163.1 - 0.00018 21.3 0.0 0.00056 19.8 0.0 1.8 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 CEP11163.1 - 0.0034 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThuA PF06283.11 CEP11163.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 Trehalose utilisation Peptidase_S51 PF03575.17 CEP11163.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 hDGE_amylase PF14701.6 CEP11164.1 - 2.8e-162 540.8 0.0 3.9e-162 540.3 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CEP11164.1 - 9.5e-119 396.7 0.0 1.4e-118 396.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CEP11164.1 - 1.4e-74 251.0 0.0 2.1e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CEP11164.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme SBF_like PF13593.6 CEP11165.1 - 6.6e-54 183.3 9.3 5.6e-48 163.9 5.7 2.1 2 0 0 2 2 2 2 SBF-like CPA transporter family (DUF4137) HTH_32 PF13565.6 CEP11165.1 - 0.0081 16.8 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CEP11165.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Transposase GP68 PF17469.2 CEP11166.1 - 0.099 13.1 0.1 0.25 11.8 0.1 1.7 1 1 0 1 1 1 0 Phage protein Gp68 Cu_amine_oxid PF01179.20 CEP11167.1 - 1.4e-26 93.4 0.1 1.8e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain PTPlike_phytase PF14566.6 CEP11168.1 - 6.2e-134 442.2 0.2 1.8e-46 158.1 0.1 3.7 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 CEP11168.1 - 1.9e-07 30.9 0.0 0.12 12.2 0.0 4.1 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP11168.1 - 0.00014 21.5 0.0 4.1 6.9 0.0 3.5 3 0 0 3 3 3 3 Protein-tyrosine phosphatase EcoEI_R_C PF08463.10 CEP11168.1 - 0.00031 20.9 1.5 0.018 15.1 0.0 3.7 4 0 0 4 4 4 1 EcoEI R protein C-terminal Y_phosphatase3 PF13350.6 CEP11168.1 - 0.0061 16.6 0.0 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 Tyrosine phosphatase family DUF2423 PF10338.9 CEP11168.1 - 0.022 15.0 2.2 2.5 8.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) Pkinase PF00069.25 CEP11169.1 - 1.5e-61 208.1 0.0 4.2e-61 206.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11169.1 - 2.7e-43 148.1 0.0 5e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP11169.1 - 7.8e-08 32.0 0.0 3.1e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP11169.1 - 2.5e-05 23.2 0.0 2.5e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP11169.1 - 0.0058 15.6 0.1 0.054 12.4 0.1 2.3 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CEP11169.1 - 0.0097 15.6 0.2 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP11169.1 - 0.027 14.4 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEP11169.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_G PF04718.15 CEP11169.1 - 0.21 12.4 0.4 2.1 9.2 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit Tim17 PF02466.19 CEP11170.1 - 0.11 12.9 0.4 0.24 11.8 0.1 1.7 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family T6_Ig_like PF18002.1 CEP11170.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 T6 antigen Ig like domain Nnf1 PF03980.14 CEP11170.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.1 3 0 0 3 3 3 0 Nnf1 Glyco_hydro_47 PF01532.20 CEP11171.1 - 8.3e-145 483.2 2.0 9.6e-145 483.0 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 CEP11171.1 - 0.0077 14.8 0.0 2.6 6.4 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 CotH PF08757.11 CEP11172.1 - 8.3e-07 28.8 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 CotH kinase protein CotH PF08757.11 CEP11173.1 - 2.8e-09 37.0 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 CotH kinase protein zf-RVT PF13966.6 CEP11174.1 - 0.00095 19.8 0.1 0.0017 19.0 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Macoilin PF09726.9 CEP11175.1 - 0.03 12.9 2.8 0.03 12.9 2.8 1.0 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 CEP11175.1 - 0.11 12.2 4.8 0.11 12.2 4.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.11 CEP11175.1 - 1.2 7.3 9.5 1.4 7.1 9.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_C12 PF01088.21 CEP11176.1 - 4.8e-61 206.2 0.1 5.6e-61 205.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUZ PF12752.7 CEP11177.1 - 4.1e-14 53.1 3.2 1.4e-13 51.4 3.2 1.9 1 0 0 1 1 1 1 SUZ domain R3H PF01424.22 CEP11177.1 - 1.7e-11 44.0 0.2 5.6e-11 42.3 0.2 1.9 1 0 0 1 1 1 1 R3H domain AA_permease PF00324.21 CEP11178.1 - 5.8e-138 460.5 41.1 7e-138 460.2 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP11178.1 - 1.6e-45 155.7 42.1 2e-45 155.4 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease PrkA PF06798.12 CEP11178.1 - 0.021 14.4 0.7 0.032 13.9 0.7 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Brr6_like_C_C PF10104.9 CEP11179.1 - 3.2e-28 98.1 2.1 5.6e-28 97.4 2.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Yqai PF09466.10 CEP11180.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai Coprogen_oxidas PF01218.18 CEP11181.1 - 1.7e-138 460.3 0.1 2e-138 460.1 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Hydantoinase_B PF02538.14 CEP11182.1 - 1.5e-219 729.7 0.6 2e-219 729.3 0.6 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CEP11182.1 - 2.6e-101 338.7 0.4 2.1e-100 335.7 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CEP11182.1 - 1.6e-35 122.4 0.1 3.3e-21 75.8 0.0 3.8 3 1 1 4 4 4 3 Hydantoinase/oxoprolinase N-terminal region Spidroin_MaSp PF11260.8 CEP11182.1 - 0.056 13.8 0.2 2.8 8.3 0.0 2.9 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 PHtD_u1 PF16645.5 CEP11183.1 - 2.6 8.6 20.4 1.9 9.0 8.1 3.1 3 0 0 3 3 3 0 Unstructured region on Pneumococcal histidine triad protein Fungal_trans PF04082.18 CEP11184.1 - 3.2e-31 108.3 2.0 1.2e-30 106.5 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP11184.1 - 5e-10 39.3 12.5 5e-10 39.3 12.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 CEP11185.1 - 4.8e-97 321.5 0.0 2.7e-47 160.5 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP11185.1 - 6.8e-28 96.2 9.7 9.2e-14 51.0 0.9 3.2 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 CEP11185.1 - 2.5e-17 62.8 0.7 8.3e-17 61.1 0.6 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CEP11185.1 - 9.8e-14 51.4 0.0 1.9e-05 24.5 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEP11185.1 - 5.4e-13 49.4 0.0 3e-07 30.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 CEP11185.1 - 5.3e-12 45.3 0.0 1.4e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 CEP11185.1 - 1.3e-11 44.9 0.0 1e-05 25.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP11185.1 - 8.5e-11 42.5 0.3 0.001 19.5 0.0 4.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CEP11185.1 - 9.5e-11 41.9 0.5 5.5e-05 23.2 0.1 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CEP11185.1 - 2e-09 37.1 0.2 0.00097 18.4 0.1 2.9 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CEP11185.1 - 5e-09 36.5 0.1 0.044 14.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEP11185.1 - 2.1e-07 31.6 0.0 0.023 15.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CEP11185.1 - 2.4e-07 30.3 0.2 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEP11185.1 - 4.2e-07 29.9 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 CEP11185.1 - 2.2e-06 28.2 0.0 0.041 14.4 0.0 3.9 3 1 0 3 3 2 2 ABC transporter RNA_helicase PF00910.22 CEP11185.1 - 2.4e-06 27.9 0.0 0.02 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 CEP11185.1 - 3.8e-06 26.6 0.0 0.02 14.4 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 CEP11185.1 - 4.2e-06 26.7 0.1 0.00014 21.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 CEP11185.1 - 5.3e-06 26.5 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 CEP11185.1 - 5.8e-06 25.6 0.1 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CEP11185.1 - 7.8e-06 26.2 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CEP11185.1 - 1.2e-05 25.1 0.0 0.39 10.4 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 CEP11185.1 - 1.6e-05 24.4 0.4 1.2 8.5 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_24 PF13479.6 CEP11185.1 - 2.1e-05 24.3 0.4 0.49 10.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CEP11185.1 - 3.6e-05 23.4 1.6 1.3 8.6 0.0 3.8 3 1 0 4 4 3 1 AAA domain DUF815 PF05673.13 CEP11185.1 - 5.2e-05 22.5 0.0 0.0091 15.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CEP11185.1 - 0.00012 22.0 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.16 CEP11185.1 - 0.00016 21.2 1.4 0.49 9.8 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein ResIII PF04851.15 CEP11185.1 - 0.00018 21.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CEP11185.1 - 0.00024 20.5 0.0 0.49 9.6 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 CEP11185.1 - 0.00024 21.1 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 CEP11185.1 - 0.00034 20.5 0.0 0.94 9.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CEP11185.1 - 0.00059 20.3 2.0 0.81 10.1 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_11 PF13086.6 CEP11185.1 - 0.00099 19.0 0.3 1.2 8.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 CEP11185.1 - 0.0016 17.8 0.0 2.4 7.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin ATPase_2 PF01637.18 CEP11185.1 - 0.0019 18.1 0.1 4.8 7.0 0.0 3.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CEP11185.1 - 0.0023 18.3 1.4 3.5 8.0 0.0 3.4 3 1 1 4 4 3 1 AAA domain NACHT PF05729.12 CEP11185.1 - 0.0049 16.8 0.1 1.1 9.1 0.0 3.1 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 CEP11185.1 - 0.0059 15.8 0.0 0.69 9.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 CEP11185.1 - 0.0066 16.2 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CEP11185.1 - 0.0072 16.1 1.8 1.8 8.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 CEP11185.1 - 0.01 16.0 0.0 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 CEP11185.1 - 0.023 14.5 0.0 8.2 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 CEP11185.1 - 0.043 13.7 2.0 3.7 7.4 0.0 3.7 4 0 0 4 4 3 0 NTPase T2SSE PF00437.20 CEP11185.1 - 0.053 12.6 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 CEP11185.1 - 0.096 13.0 1.9 80 3.4 0.0 4.0 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain IPT PF01745.16 CEP11185.1 - 0.12 11.8 0.1 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase RVT_1 PF00078.27 CEP11186.1 - 0.00053 19.6 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_U47 PF05467.11 CEP11186.1 - 0.00055 18.2 1.4 0.00069 17.9 1.4 1.1 1 0 0 1 1 1 1 Herpesvirus glycoprotein U47 HIT PF01230.23 CEP11187.1 - 1.4e-14 54.6 0.0 2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CEP11187.1 - 0.00011 22.6 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PH PF00169.29 CEP11188.1 - 1.2e-06 29.0 0.0 2.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 PH domain KELK PF15796.5 CEP11188.1 - 0.21 12.1 1.2 0.6 10.6 0.9 1.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Kinesin PF00225.23 CEP11189.1 - 1.3e-97 326.7 1.9 1.3e-97 326.7 1.9 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP11189.1 - 1.2e-22 80.5 1.6 2.6e-22 79.4 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding Nexin_C PF08628.12 CEP11189.1 - 0.77 10.4 5.3 1.8 9.2 4.3 2.2 1 1 0 1 1 1 0 Sorting nexin C terminal Pyridoxal_deC PF00282.19 CEP11190.1 - 4.8e-79 265.8 0.0 6.7e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CEP11190.1 - 1.5e-05 24.1 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEP11190.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cation_efflux PF01545.21 CEP11191.1 - 9.5e-53 178.9 13.5 1.5e-52 178.2 13.5 1.3 1 0 0 1 1 1 1 Cation efflux family DUF2838 PF10998.8 CEP11192.1 - 1.9e-41 140.8 10.1 1.9e-41 140.8 10.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Ribosomal_S28e PF01200.18 CEP11193.1 - 3.8e-33 113.3 1.1 4.5e-33 113.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 CEP11193.1 - 0.093 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal ADIP PF11559.8 CEP11194.1 - 3.2e-22 79.3 15.7 3.2e-22 79.3 15.7 3.8 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding DUF3113 PF11310.8 CEP11194.1 - 0.05 13.6 1.2 0.64 10.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) PRK PF00485.18 CEP11194.1 - 1.9 8.2 7.6 0.45 10.2 3.8 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Prp19 PF08606.11 CEP11194.1 - 3 7.9 8.1 2.1 8.4 0.2 3.8 3 1 0 3 3 3 0 Prp19/Pso4-like Mso1_Sec1_bdg PF14475.6 CEP11195.1 - 9.9e-06 25.1 0.1 3.3e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Sec1-binding region of Mso1 FAA_hydrolase PF01557.18 CEP11196.1 - 1.6e-57 194.7 0.0 2.2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CEP11196.1 - 7.7e-36 122.5 0.0 1.6e-35 121.5 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Phage-tail_3 PF13550.6 CEP11196.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative phage tail protein Glyco_hydro_15 PF00723.21 CEP11197.1 - 3.7e-59 200.7 0.0 9.9e-58 196.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF2865 PF11064.8 CEP11197.1 - 0.025 15.0 0.3 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2865) SPC25 PF06703.11 CEP11198.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Methyltransf_25 PF13649.6 CEP11200.1 - 6.6e-17 62.0 0.0 1.8e-14 54.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11200.1 - 7.4e-16 58.6 0.0 3.8e-12 46.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11200.1 - 9.9e-14 51.5 0.0 3.8e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP11200.1 - 8.5e-13 48.4 0.0 6e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP11200.1 - 1.3e-08 35.5 0.0 4.5e-08 33.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 CEP11200.1 - 1.2e-07 32.0 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 CEP11200.1 - 3.3e-05 23.4 0.0 0.00035 20.1 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 CEP11200.1 - 0.0021 17.4 0.0 0.011 15.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CEP11200.1 - 0.0083 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CEP11200.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 CEP11200.1 - 0.017 14.5 0.0 0.036 13.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CEP11200.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Gpr1_Fun34_YaaH PF01184.19 CEP11201.1 - 2.4e-25 89.4 21.1 3.7e-25 88.7 21.1 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 12TM_1 PF09847.9 CEP11201.1 - 0.0059 15.8 2.4 0.011 14.9 2.4 1.3 1 0 0 1 1 1 1 Membrane protein of 12 TMs TLV_coat PF00429.19 CEP11201.1 - 0.012 14.4 0.6 0.015 14.0 0.6 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF5031 PF16434.5 CEP11201.1 - 0.056 12.6 0.2 0.08 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) Mnd1 PF03962.15 CEP11201.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Mnd1 HTH domain Itfg2 PF15907.5 CEP11202.1 - 9.4e-37 126.8 26.1 5.4e-17 61.8 4.3 7.3 6 2 0 6 6 6 5 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CEP11202.1 - 0.0025 18.4 0.1 1.1 9.9 0.1 3.6 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PcfJ PF14284.6 CEP11202.1 - 0.0043 17.0 1.1 0.034 14.0 0.5 2.4 2 0 0 2 2 2 1 PcfJ-like protein BBS2_Mid PF14783.6 CEP11202.1 - 0.0084 16.1 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 CEP11202.1 - 0.62 10.3 4.2 9.8 6.4 0.4 2.7 2 0 0 2 2 2 0 FG-GAP repeat Chromo PF00385.24 CEP11206.1 - 2e-06 27.6 0.1 2.8e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 CEP11207.1 - 0.0002 21.2 10.6 0.026 14.6 1.8 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP11207.1 - 0.027 14.2 3.2 0.027 14.2 3.2 2.6 3 0 0 3 3 3 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP11207.1 - 0.3 11.0 11.3 0.13 12.2 2.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.6 CEP11209.1 - 3.6e-08 33.3 0.3 3.6e-08 33.3 0.3 2.5 2 2 1 3 3 3 1 Endonuclease-reverse transcriptase RL10P_insert PF17777.1 CEP11210.1 - 2.9e-22 78.5 0.0 5.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CEP11210.1 - 1.7e-09 38.1 1.1 6.5e-09 36.3 0.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 CEP11210.1 - 0.069 13.3 0.1 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L10 RVT_1 PF00078.27 CEP11211.1 - 1.2e-05 24.9 0.1 1.7e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tti2 PF10521.9 CEP11213.1 - 2.9e-32 112.3 0.2 1.2e-16 61.1 0.1 2.1 1 1 1 2 2 2 2 Tti2 family CDP-OH_P_transf PF01066.21 CEP11214.1 - 3.7e-18 66.1 0.2 3.7e-18 66.1 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pyr_redox_2 PF07992.14 CEP11215.1 - 1e-08 34.8 0.0 3.4e-08 33.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP11215.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEP11215.1 - 0.0024 18.0 0.0 0.0057 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3808 PF10300.9 CEP11216.1 - 2.1e-62 211.5 9.3 3.6e-62 210.7 9.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CEP11216.1 - 0.0039 17.2 0.8 3.1 8.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Pox_RNA_Pol_19 PF05320.12 CEP11216.1 - 0.75 9.7 4.4 3.1 7.8 4.4 2.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.12 CEP11216.1 - 4.7 6.4 7.6 9.4 5.5 7.6 1.4 1 0 0 1 1 1 0 NOA36 protein MutL_C PF08676.11 CEP11217.1 - 2.4e-11 43.6 0.2 3.5e-07 30.1 0.1 2.5 2 0 0 2 2 2 2 MutL C terminal dimerisation domain TMEM171 PF15471.6 CEP11217.1 - 0.017 14.1 0.5 0.026 13.5 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Phage_tail_L PF05100.12 CEP11217.1 - 0.074 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage minor tail protein L DNA_pol3_delt_C PF14840.6 CEP11217.1 - 0.13 12.6 0.5 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term GDC-P PF02347.16 CEP11218.1 - 2.3e-202 672.5 0.1 1.3e-189 630.5 0.1 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CEP11218.1 - 6.9e-07 28.5 0.8 2.2e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEP11218.1 - 1.2e-05 24.8 0.4 0.00011 21.6 0.1 2.3 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CEP11218.1 - 0.0082 14.7 0.1 1.1 7.7 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DUF1805 PF08827.11 CEP11218.1 - 0.074 13.4 0.0 0.3 11.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) BCDHK_Adom3 PF10436.9 CEP11219.1 - 1e-53 181.5 0.0 3.6e-53 179.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Methyltransf_25 PF13649.6 CEP11219.1 - 1.3e-16 61.1 0.0 3.4e-16 59.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11219.1 - 1.4e-15 57.7 0.0 3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP11219.1 - 4e-13 49.4 0.0 8e-12 45.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11219.1 - 8.3e-09 35.5 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEP11219.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 CEP11219.1 - 1e-07 31.6 0.0 3.7e-07 29.7 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family HATPase_c PF02518.26 CEP11219.1 - 7.9e-07 29.6 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_12 PF08242.12 CEP11219.1 - 3.4e-06 27.7 0.0 9.3e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP11219.1 - 5.1e-05 22.8 0.0 0.00025 20.6 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_2 PF00891.18 CEP11219.1 - 0.00095 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 CEP11219.1 - 0.0011 19.1 0.0 0.0043 17.2 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase HATPase_c_3 PF13589.6 CEP11219.1 - 0.0019 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MTS PF05175.14 CEP11219.1 - 0.032 13.8 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Crust_neurohorm PF01147.17 CEP11219.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Glyco_hydro_31 PF01055.26 CEP11220.1 - 8e-144 480.1 6.4 1e-143 479.7 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CEP11220.1 - 7.5e-31 106.7 0.8 1.5e-30 105.8 0.8 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CEP11220.1 - 8.9e-08 32.3 0.2 2.7e-07 30.8 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like UPF0524 PF15823.5 CEP11220.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 CAP_GLY PF01302.25 CEP11221.1 - 3.6e-17 62.1 0.1 5.2e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain HLH PF00010.26 CEP11222.1 - 2.9e-13 49.5 1.3 7.1e-13 48.3 1.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ins_allergen_rp PF06757.13 CEP11222.1 - 0.0032 17.5 0.1 0.0044 17.0 0.1 1.3 1 1 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification Glycogen_syn PF05693.13 CEP11222.1 - 0.03 12.9 0.6 0.036 12.6 0.6 1.0 1 0 0 1 1 1 0 Glycogen synthase ZapB PF06005.12 CEP11222.1 - 2.3 8.7 6.7 1.2 9.7 0.2 2.6 2 1 0 2 2 2 0 Cell division protein ZapB Nnf1 PF03980.14 CEP11223.1 - 6.6e-07 29.7 2.0 9.6e-07 29.2 1.3 1.6 1 1 0 1 1 1 1 Nnf1 PgdA_N PF18627.1 CEP11223.1 - 0.0072 16.0 1.3 0.011 15.3 1.3 1.3 1 0 0 1 1 1 1 Peptidoglycan GlcNAc deacetylase N-terminal domain BCDHK_Adom3 PF10436.9 CEP11223.1 - 0.032 14.1 1.1 0.26 11.1 1.1 2.0 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF5617 PF18493.1 CEP11223.1 - 0.062 13.4 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) CI-B14_5a PF07347.12 CEP11224.1 - 0.00063 19.6 0.7 0.0016 18.2 0.6 1.8 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Mito_carr PF00153.27 CEP11225.1 - 2.7e-70 232.3 0.2 7.3e-23 80.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP11225.1 - 0.00018 20.8 0.1 0.00062 19.0 0.1 2.0 1 1 0 1 1 1 1 Gammaproteobacterial serine protease Sas10_Utp3 PF04000.15 CEP11226.1 - 0.0041 17.7 3.5 0.011 16.4 0.2 2.7 2 1 1 3 3 3 1 Sas10/Utp3/C1D family DUF4820 PF16091.5 CEP11226.1 - 0.023 14.1 3.6 0.025 13.9 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) IPT PF01745.16 CEP11227.1 - 0.051 12.9 3.3 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase DNA_gyraseA_C PF03989.13 CEP11227.1 - 0.19 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller GNAT_acetyltr_2 PF13718.6 CEP11228.1 - 3.3e-99 330.9 0.0 3.3e-99 330.9 0.0 2.3 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CEP11228.1 - 7.5e-89 297.5 0.3 7.5e-89 297.5 0.3 1.6 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CEP11228.1 - 6.7e-66 221.5 0.0 1.8e-65 220.1 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CEP11228.1 - 1.5e-33 114.6 0.1 4.2e-33 113.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CEP11228.1 - 0.011 16.0 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEP11228.1 - 0.021 15.2 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CEP11228.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_7 PF13508.7 CEP11228.1 - 0.11 12.9 0.0 0.76 10.2 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP11228.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family OAD_gamma PF04277.13 CEP11228.1 - 8.2 7.1 6.6 1.3 9.7 0.2 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GMC_oxred_N PF00732.19 CEP11229.1 - 1.2e-37 129.9 0.1 3.2e-37 128.5 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEP11229.1 - 1.8e-20 74.0 0.1 3.4e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEP11229.1 - 1.1e-07 31.4 3.5 7.6e-05 22.0 1.7 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CEP11229.1 - 5.2e-05 22.6 1.5 0.0004 19.7 0.7 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP11229.1 - 0.0078 16.4 1.9 0.0078 16.4 1.9 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP11229.1 - 0.017 14.7 3.8 0.098 12.2 1.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 CEP11229.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 CEP11229.1 - 0.061 12.0 1.3 0.081 11.6 0.5 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CEP11229.1 - 0.098 11.9 0.4 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CEP11229.1 - 0.11 11.8 3.1 0.18 11.1 3.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP11229.1 - 0.15 11.2 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CEP11230.1 - 6.3e-34 117.7 2.0 4.8e-20 72.1 1.1 3.0 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CEP11230.1 - 1.1e-21 77.8 2.3 1.1e-21 77.8 0.0 2.3 2 0 0 2 2 1 1 GMC oxidoreductase HLH PF00010.26 CEP11230.1 - 2.1e-11 43.6 0.2 4.7e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAD_binding_2 PF00890.24 CEP11230.1 - 1.2e-09 37.8 4.1 1.5e-06 27.6 1.9 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CEP11230.1 - 1.4e-06 28.4 0.6 1e-05 25.7 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP11230.1 - 1.6e-06 27.6 2.5 1e-05 24.9 2.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP11230.1 - 0.0001 22.0 6.5 0.0038 16.9 6.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEP11230.1 - 0.00023 20.5 0.3 0.00049 19.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CEP11230.1 - 0.0006 19.3 3.4 0.0014 18.0 3.4 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP11230.1 - 0.0014 17.5 0.6 0.0014 17.5 0.6 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CEP11230.1 - 0.0014 18.0 0.2 0.23 10.7 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP11230.1 - 0.0058 15.8 0.4 0.0058 15.8 0.4 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 CEP11230.1 - 0.016 14.5 1.1 0.042 13.1 0.8 1.8 1 1 0 1 1 1 0 Thi4 family ApbA PF02558.16 CEP11230.1 - 0.021 14.5 0.2 0.064 12.9 0.2 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 CEP11230.1 - 0.17 10.9 0.1 0.33 10.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein YjeF_N PF03853.15 CEP11230.1 - 0.29 11.0 1.3 4.5 7.1 0.1 3.1 3 0 0 3 3 3 0 YjeF-related protein N-terminus ArfGap PF01412.18 CEP11231.1 - 1e-20 73.9 0.1 2.7e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Complex1_30kDa PF00329.19 CEP11232.1 - 2.2e-46 157.5 0.0 3e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Syntaxin-18_N PF10496.9 CEP11234.1 - 3.7e-13 49.5 2.9 3.7e-13 49.5 2.9 4.1 3 2 1 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CEP11234.1 - 2.6e-05 24.1 0.2 8.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 SNARE domain SUIM_assoc PF16619.5 CEP11234.1 - 1.2 9.3 16.6 0.96 9.6 13.5 2.6 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 E1-E2_ATPase PF00122.20 CEP11235.1 - 1.5e-33 115.8 0.4 3e-33 114.9 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 CEP11235.1 - 1.1e-27 96.6 1.5 3.4e-27 95.0 1.5 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 CEP11235.1 - 7.9e-14 52.4 0.1 3.9e-06 27.3 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP11235.1 - 2.8e-05 24.1 0.0 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEP11235.1 - 9.6e-05 22.0 0.0 0.00025 20.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HSF_DNA-bind PF00447.17 CEP11236.1 - 6.3e-06 26.7 0.1 6.3e-06 26.7 0.1 3.2 3 1 0 3 3 3 1 HSF-type DNA-binding Striatin PF08232.12 CEP11236.1 - 0.027 15.1 0.4 0.027 15.1 0.4 3.3 2 2 1 3 3 3 0 Striatin family SelP_N PF04592.14 CEP11236.1 - 0.069 12.5 27.6 0.23 10.8 27.6 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SART-1 PF03343.13 CEP11236.1 - 0.07 11.7 18.1 0.1 11.2 18.1 1.2 1 0 0 1 1 1 0 SART-1 family FHIPEP PF00771.20 CEP11236.1 - 0.3 9.5 3.9 0.36 9.2 3.9 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.6 CEP11236.1 - 1.4 6.8 30.8 2.1 6.2 30.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OATP PF03137.20 CEP11236.1 - 3.4 5.9 6.4 6.6 4.9 6.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3347 PF11827.8 CEP11236.1 - 8.3 6.6 20.1 0.49 10.6 13.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Chromo PF00385.24 CEP11239.1 - 4.5e-10 39.3 0.6 7.7e-10 38.5 0.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP11239.1 - 0.00062 19.6 1.3 0.0045 16.8 0.2 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Tup_N PF08581.10 CEP11240.1 - 0.13 12.6 0.1 0.18 12.1 0.0 1.3 1 1 0 1 1 1 0 Tup N-terminal RabGAP-TBC PF00566.18 CEP11243.1 - 3.2e-38 131.6 5.2 4.2e-25 88.7 0.1 3.8 2 1 1 3 3 3 2 Rab-GTPase-TBC domain GRAM PF02893.20 CEP11243.1 - 8e-13 48.3 3.9 5.5e-08 32.7 0.5 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_6 PF13405.6 CEP11243.1 - 0.049 13.6 0.2 0.26 11.3 0.2 2.3 1 0 0 1 1 1 0 EF-hand domain DUF1476 PF07345.11 CEP11243.1 - 0.099 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta EF-hand_1 PF00036.32 CEP11243.1 - 0.11 12.1 0.1 0.43 10.2 0.1 2.2 1 0 0 1 1 1 0 EF hand DUF4032 PF13224.6 CEP11244.1 - 0.051 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) DNA_pol_A_exo1 PF01612.20 CEP11245.1 - 1.2e-10 41.3 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RVT_1 PF00078.27 CEP11246.1 - 2e-28 99.4 0.0 2.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) M20_dimer PF07687.14 CEP11247.1 - 9.9e-11 41.5 0.0 2.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CEP11247.1 - 2.2e-08 34.0 0.0 4e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DP-EP PF08985.11 CEP11247.1 - 0.014 15.5 0.1 0.035 14.3 0.1 1.7 1 0 0 1 1 1 0 DP-EP family p450 PF00067.22 CEP11248.1 - 5.9e-78 262.7 0.0 7.3e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.23 CEP11249.1 - 6.2e-09 35.7 0.0 9.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP11249.1 - 3.2e-05 24.4 0.1 0.0005 20.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin DUF2846 PF11008.8 CEP11249.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Ribosomal_L7Ae PF01248.26 CEP11250.1 - 8.9e-23 79.9 1.5 1.7e-22 79.0 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 CEP11250.1 - 0.056 13.4 0.9 0.1 12.5 0.9 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GalP_UDP_tr_C PF02744.17 CEP11250.1 - 0.15 11.8 1.3 17 5.1 0.0 2.9 2 1 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Ribosomal_L18A PF01775.17 CEP11251.1 - 1e-51 174.1 2.2 1.3e-51 173.8 2.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A AAA PF00004.29 CEP11252.1 - 9.4e-97 320.5 0.0 5.9e-49 165.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP11252.1 - 1.1e-21 76.4 3.3 1.2e-10 41.0 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CEP11252.1 - 1.1e-16 61.0 0.0 2.5e-09 37.1 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEP11252.1 - 1.6e-12 47.6 0.8 0.00012 22.1 0.0 4.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP11252.1 - 2.4e-12 47.6 4.9 0.00078 19.9 0.0 4.7 3 2 2 5 5 4 2 AAA ATPase domain AAA_2 PF07724.14 CEP11252.1 - 4.9e-11 43.0 0.0 0.00012 22.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CEP11252.1 - 3.5e-10 40.2 0.0 0.00025 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEP11252.1 - 1.4e-09 38.4 0.8 0.017 15.4 0.1 4.6 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CEP11252.1 - 4.6e-09 35.9 0.0 0.00015 21.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CEP11252.1 - 6.5e-08 32.7 0.0 0.0042 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEP11252.1 - 8.2e-08 32.6 0.0 0.022 15.1 0.0 3.1 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.12 CEP11252.1 - 5.6e-07 29.6 0.2 0.11 12.4 0.0 4.3 4 0 0 4 4 4 2 NACHT domain IstB_IS21 PF01695.17 CEP11252.1 - 5.8e-07 29.4 0.0 0.032 14.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CEP11252.1 - 1.4e-06 28.8 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CEP11252.1 - 2.1e-06 27.1 0.0 0.056 12.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 CEP11252.1 - 3.7e-06 27.3 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEP11252.1 - 4.3e-06 26.7 0.0 0.071 13.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CEP11252.1 - 6.3e-06 25.7 0.3 0.064 12.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 CEP11252.1 - 7.9e-06 26.1 0.0 0.003 17.7 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_7 PF12775.7 CEP11252.1 - 1e-05 25.1 0.0 0.58 9.6 0.0 3.6 3 1 0 3 3 3 2 P-loop containing dynein motor region AAA_25 PF13481.6 CEP11252.1 - 1.5e-05 24.7 6.2 1.5 8.3 0.0 4.8 4 1 1 5 5 4 2 AAA domain ABC_tran PF00005.27 CEP11252.1 - 2.7e-05 24.7 0.0 0.47 11.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 CEP11252.1 - 5.9e-05 23.5 0.0 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 CEP11252.1 - 6.2e-05 23.0 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain DUF815 PF05673.13 CEP11252.1 - 7.7e-05 22.0 0.0 0.018 14.2 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CEP11252.1 - 8.1e-05 22.4 0.0 0.23 11.1 0.0 3.7 4 0 0 4 4 3 1 Sigma-54 interaction domain ATPase PF06745.13 CEP11252.1 - 8.5e-05 22.0 0.1 1 8.7 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_3 PF07726.11 CEP11252.1 - 0.00012 21.9 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CEP11252.1 - 0.00022 21.1 0.1 0.72 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 CEP11252.1 - 0.00025 21.0 0.0 2.5 8.0 0.0 3.8 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea SKI PF01202.22 CEP11252.1 - 0.00033 20.8 0.0 0.44 10.7 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.18 CEP11252.1 - 0.00059 19.6 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 CEP11252.1 - 0.00064 19.0 0.0 0.86 8.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 CEP11252.1 - 0.00072 19.3 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 CEP11252.1 - 0.0014 18.6 0.4 2.1 8.4 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 CEP11252.1 - 0.002 17.3 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.25 CEP11252.1 - 0.0038 16.9 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.12 CEP11252.1 - 0.0061 16.4 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 CEP11252.1 - 0.0067 15.8 0.0 3 7.2 0.0 3.4 3 1 0 3 3 3 1 Bacterial TniB protein Sigma54_activ_2 PF14532.6 CEP11252.1 - 0.0077 16.4 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 CEP11252.1 - 0.0093 15.9 1.5 5.7 6.8 0.0 3.3 3 1 0 3 3 3 0 NTPase AFG1_ATPase PF03969.16 CEP11252.1 - 0.0099 14.8 0.0 2.4 7.0 0.0 2.6 3 0 0 3 3 2 1 AFG1-like ATPase Bac_DnaA PF00308.18 CEP11252.1 - 0.012 15.4 0.0 7.2 6.4 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein PhoH PF02562.16 CEP11252.1 - 0.015 14.7 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PduV-EutP PF10662.9 CEP11252.1 - 0.017 14.9 0.0 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CEP11252.1 - 0.036 14.4 4.1 3.7 7.9 1.4 3.5 2 1 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CEP11252.1 - 0.056 13.2 0.0 7 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase DUF908 PF06012.12 CEP11252.1 - 0.29 10.5 3.7 0.5 9.7 3.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) F-box-like PF12937.7 CEP11253.1 - 3.1e-05 23.8 0.3 7.9e-05 22.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP11253.1 - 0.12 12.3 0.8 0.31 11.0 0.8 1.8 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.28 CEP11254.1 - 1.2e-14 53.3 7.6 0.0055 16.5 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP11254.1 - 2.6e-13 49.6 19.7 0.0019 18.8 0.1 9.7 8 2 3 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11254.1 - 2e-12 47.4 15.7 3.4e-05 24.3 0.0 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11254.1 - 6.6e-10 39.5 11.9 0.00087 19.9 0.1 5.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP11254.1 - 3.2e-09 36.2 12.6 0.062 13.5 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11254.1 - 2.8e-07 30.4 7.1 3.1 8.4 0.2 8.3 10 0 0 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP11254.1 - 5.7e-07 29.7 13.8 0.7 10.2 0.0 6.9 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEP11254.1 - 1.7e-05 24.6 11.4 0.61 10.5 0.0 7.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP11254.1 - 2.5e-05 24.0 6.0 0.32 11.1 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEP11254.1 - 0.00029 20.1 14.1 0.014 14.6 0.0 4.9 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11254.1 - 0.00035 20.2 6.8 0.6 9.8 0.0 6.1 7 0 0 7 7 7 1 TPR repeat TPR_20 PF14561.6 CEP11254.1 - 0.00065 20.0 3.1 0.084 13.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 CEP11254.1 - 0.005 16.6 0.3 1.4 8.6 0.0 3.0 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 CEP11254.1 - 0.0066 17.0 6.2 11 7.0 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP11254.1 - 0.024 14.8 4.0 9.1 6.5 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11254.1 - 0.055 13.8 12.0 0.25 11.6 0.0 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat IBR PF01485.21 CEP11255.1 - 0.00035 20.7 2.7 0.00035 20.7 2.7 4.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 CEP11255.1 - 0.0031 17.3 8.1 0.0031 17.3 8.1 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.13 CEP11255.1 - 0.053 13.7 1.8 0.053 13.7 1.8 4.6 5 0 0 5 5 5 0 Piccolo Zn-finger Cu_amine_oxid PF01179.20 CEP11256.1 - 4.5e-33 114.8 1.6 1.8e-32 112.8 1.6 1.7 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 CEP11257.1 - 6.4e-23 81.3 0.0 7.3e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Integrase_H2C2 PF17921.1 CEP11259.1 - 5.5e-23 80.8 1.7 2e-22 79.1 0.3 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain Chromo PF00385.24 CEP11259.1 - 2.1e-15 56.4 0.6 4.4e-15 55.3 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP11259.1 - 2.8e-15 56.5 0.0 5.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP11259.1 - 0.00026 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Helitron_like_N PF14214.6 CEP11262.1 - 2.2e-23 83.4 0.1 4.1e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phe_ZIP PF08916.11 CEP11262.1 - 0.012 16.3 0.6 0.05 14.3 0.2 2.2 2 0 0 2 2 2 0 Phenylalanine zipper IL4Ra_N PF09238.10 CEP11262.1 - 0.052 13.9 3.3 0.51 10.7 2.3 2.4 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal LIFR_D2 PF17971.1 CEP11262.1 - 0.09 13.0 0.2 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Leukemia inhibitory factor receptor D2 domain RGI1 PF10843.8 CEP11262.1 - 0.15 11.7 2.9 0.98 9.0 0.3 2.9 3 1 0 3 3 3 0 Respiratory growth induced protein 1 DUF677 PF05055.12 CEP11265.1 - 0.042 12.7 3.6 0.055 12.4 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF677) DUF5510 PF17629.2 CEP11265.1 - 0.26 11.2 3.3 0.44 10.5 3.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5510) ABC2_membrane_2 PF12679.7 CEP11265.1 - 3.2 7.0 10.1 3.5 6.8 10.1 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4148 PF13663.6 CEP11265.1 - 10 6.4 8.1 67 3.8 8.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) GAGA PF09237.11 CEP11266.1 - 0.32 10.8 2.3 0.43 10.4 2.3 1.2 1 0 0 1 1 1 0 GAGA factor PIG-L PF02585.17 CEP11268.1 - 0.056 14.1 0.0 0.095 13.3 0.0 1.3 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase DUF4686 PF15742.5 CEP11269.1 - 3.4e-05 23.2 4.0 4.1e-05 22.9 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DUF4939 PF16297.5 CEP11269.1 - 0.00079 19.3 0.1 0.0014 18.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4939) Allexi_40kDa PF05549.11 CEP11269.1 - 0.00083 19.0 3.2 0.0011 18.6 3.2 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein HMMR_N PF15905.5 CEP11269.1 - 0.023 14.2 7.7 0.03 13.8 7.7 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal YPEB PF14620.6 CEP11269.1 - 0.035 13.4 3.4 0.044 13.1 3.4 1.1 1 0 0 1 1 1 0 YpeB sporulation FlgN PF05130.12 CEP11269.1 - 0.046 14.2 5.9 0.066 13.7 5.9 1.2 1 0 0 1 1 1 0 FlgN protein Baculo_PEP_C PF04513.12 CEP11269.1 - 0.053 13.6 6.5 0.078 13.0 6.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CEP11269.1 - 0.057 12.3 6.3 0.072 12.0 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2240 PF09999.9 CEP11269.1 - 0.059 13.0 0.4 0.096 12.3 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) WASH-7_C PF14746.6 CEP11269.1 - 0.085 12.6 2.2 0.13 11.9 2.2 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal ApoO PF09769.9 CEP11269.1 - 0.19 11.7 1.2 9.3 6.2 0.2 2.1 1 1 1 2 2 2 0 Apolipoprotein O DASH_Dad3 PF08656.10 CEP11269.1 - 0.26 11.4 3.7 0.68 10.1 3.7 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 RAC_head PF16717.5 CEP11269.1 - 0.45 11.5 4.7 0.8 10.7 3.8 1.8 1 1 1 2 2 2 0 Ribosome-associated complex head domain DUF1664 PF07889.12 CEP11269.1 - 0.62 10.1 4.8 2.1 8.4 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AI-2E_transport PF01594.16 CEP11269.1 - 0.63 9.1 2.3 0.83 8.7 2.3 1.1 1 0 0 1 1 1 0 AI-2E family transporter zf-CCHC PF00098.23 CEP11272.1 - 0.0002 21.3 2.0 0.0003 20.7 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEP11272.1 - 0.0006 20.0 1.0 0.0017 18.6 1.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP11273.1 - 1.3e-08 35.3 0.0 6e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP11273.1 - 0.00014 22.4 0.0 0.001 19.6 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP11273.1 - 0.0092 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP11273.1 - 0.15 11.8 0.2 0.34 10.7 0.2 1.5 2 0 0 2 2 2 0 Aspartyl protease DDE_3 PF13358.6 CEP11274.1 - 6.8e-26 90.8 0.0 1.4e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L23eN PF03939.13 CEP11274.1 - 3.3e-22 78.4 11.2 7.4e-22 77.3 11.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CEP11274.1 - 1.1e-14 54.6 4.3 2.4e-14 53.5 1.7 2.9 2 1 0 2 2 2 1 Ribosomal protein L23 HTH_33 PF13592.6 CEP11274.1 - 0.011 15.4 0.0 0.042 13.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix Tox-URI2 PF15653.6 CEP11274.1 - 0.093 13.0 1.3 10 6.5 0.0 2.8 2 0 0 2 2 2 0 URI fold toxin 2 RabGAP-TBC PF00566.18 CEP11275.1 - 1.1e-54 185.3 0.5 1.1e-54 185.3 0.5 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mod_r PF07200.13 CEP11275.1 - 0.00012 22.2 17.6 0.027 14.6 4.9 2.7 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 CEP11275.1 - 0.0066 16.5 20.3 0.012 15.6 20.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 CEP11275.1 - 0.037 14.1 9.0 0.21 11.7 3.2 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAV_VP PF12944.7 CEP11275.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP UPF0242 PF06785.11 CEP11275.1 - 0.068 13.3 14.1 0.15 12.2 14.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZYG-11_interact PF05884.12 CEP11275.1 - 0.21 11.0 3.2 0.43 9.9 3.2 1.5 1 0 0 1 1 1 0 Interactor of ZYG-11 HIP1_clath_bdg PF16515.5 CEP11275.1 - 0.41 11.3 15.9 0.22 12.1 12.4 2.5 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1410 PF07198.11 CEP11275.1 - 1.9 9.0 4.7 0.6 10.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) CENP-H PF05837.12 CEP11275.1 - 9.2 6.7 18.8 18 5.8 6.1 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DNA_primase_lrg PF04104.14 CEP11276.1 - 1.4e-86 290.2 0.5 1.4e-86 290.2 0.5 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit DUF501 PF04417.12 CEP11276.1 - 0.035 13.9 1.0 7 6.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF501) Curto_V2 PF07325.11 CEP11276.1 - 0.54 10.1 5.3 11 6.0 0.4 3.6 3 1 1 4 4 4 0 Curtovirus V2 protein ATG13 PF10033.9 CEP11278.1 - 9e-40 136.9 0.6 1.7e-39 136.0 0.6 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 SIS PF01380.22 CEP11279.1 - 3.9e-64 214.4 0.3 1.2e-33 115.8 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CEP11279.1 - 2.7e-17 63.2 0.0 5.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEP11279.1 - 9.8e-13 48.1 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CEP11279.1 - 0.00045 19.2 0.0 0.00073 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CEP11279.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 SIS domain DUF4218 PF13960.6 CEP11280.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RTT107_BRCT_5 PF16770.5 CEP11281.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Tsp45I PF06300.12 CEP11281.1 - 0.033 13.7 0.5 3.2 7.2 0.2 2.0 2 0 0 2 2 2 0 Tsp45I type II restriction enzyme Mem_trans PF03547.18 CEP11283.1 - 0.32 9.3 1.6 0.33 9.3 1.6 1.1 1 0 0 1 1 1 0 Membrane transport protein CobT PF06213.12 CEP11283.1 - 0.54 9.6 11.6 6 6.2 9.7 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF1616 PF07760.11 CEP11283.1 - 0.69 9.2 4.4 1.1 8.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) RhoGAP PF00620.27 CEP11285.1 - 2e-47 160.8 1.4 2.9e-47 160.3 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CEP11285.1 - 4.4e-05 23.9 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1708 PF08101.11 CEP11285.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Rax2 PF12768.7 CEP11286.1 - 1.4e-29 103.1 9.2 3.8e-29 101.7 0.2 4.0 4 0 0 4 4 4 1 Cortical protein marker for cell polarity SH3_9 PF14604.6 CEP11286.1 - 6.4e-11 41.9 0.1 1.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP11286.1 - 8.7e-08 31.7 0.1 1.8e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP11286.1 - 1.2e-06 28.0 0.1 3.3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Kelch_1 PF01344.25 CEP11286.1 - 0.07 12.7 0.0 57 3.4 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CEP11286.1 - 0.25 11.4 2.0 1.4e+02 2.6 0.0 5.2 6 0 0 6 6 6 0 Kelch motif Brix PF04427.18 CEP11287.1 - 1.7e-39 136.0 0.0 2.5e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain GDA1_CD39 PF01150.17 CEP11288.1 - 1.9e-120 402.4 0.0 2.7e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EamA PF00892.20 CEP11289.1 - 9.5e-12 45.3 30.3 3.8e-06 27.1 5.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CEP11289.1 - 5.8e-06 26.0 11.7 7.9e-06 25.6 11.7 1.2 1 0 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 CEP11289.1 - 0.00024 20.4 1.0 0.00024 20.4 1.0 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TPT PF03151.16 CEP11289.1 - 0.0094 15.3 2.6 0.0094 15.3 2.6 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family GCP_C_terminal PF04130.13 CEP11290.1 - 8.9e-75 252.0 8.9 8.9e-75 252.0 8.9 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEP11290.1 - 1.2e-70 238.6 0.6 2.6e-70 237.5 0.6 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Ras PF00071.22 CEP11291.1 - 3.2e-51 173.2 0.3 1.2e-50 171.3 0.3 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CEP11291.1 - 2.9e-31 108.2 0.3 2.3e-30 105.3 0.1 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP11291.1 - 3.2e-11 43.0 0.1 3.8e-11 42.7 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP11291.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP11291.1 - 0.00045 19.8 0.0 0.0011 18.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP11291.1 - 0.0036 17.2 0.2 0.17 11.8 0.0 2.6 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEP11291.1 - 0.0038 17.6 0.1 0.029 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 CEP11291.1 - 0.016 14.6 0.1 0.046 13.1 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CEP11291.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CEP11291.1 - 0.081 13.2 0.0 1.1 9.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain DNA_gyraseA_C PF03989.13 CEP11291.1 - 0.13 11.7 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller NAD_binding_10 PF13460.6 CEP11292.1 - 4.6e-11 42.9 0.0 7.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP11292.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family UQ_con PF00179.26 CEP11293.1 - 1.6e-47 160.7 0.0 1.8e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP11293.1 - 0.0015 18.8 0.0 0.0016 18.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CEP11293.1 - 0.0015 18.2 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEP11293.1 - 0.066 13.1 0.3 0.11 12.4 0.3 1.4 1 1 0 1 1 1 0 UEV domain WD40 PF00400.32 CEP11294.1 - 4.4e-17 62.1 0.3 0.00012 22.8 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11294.1 - 2.2e-09 37.5 0.0 0.027 14.8 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP11294.1 - 0.0075 15.0 0.0 2.2 6.8 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF4934 PF16288.5 CEP11294.1 - 0.048 13.6 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) ENTH PF01417.20 CEP11295.1 - 1e-45 154.8 0.0 1.7e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CEP11295.1 - 1.9e-05 23.8 0.0 4.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 CEP11295.1 - 0.00064 19.5 6.3 0.043 13.7 0.2 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif eIF3_subunit PF08597.10 CEP11295.1 - 2.9 7.7 12.5 0.71 9.7 9.0 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CBM_21 PF03370.13 CEP11296.1 - 4.4e-23 81.6 4.3 1e-22 80.5 4.3 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEP11296.1 - 1.2e-14 54.6 4.1 2.5e-14 53.6 4.1 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Nop53 PF07767.11 CEP11297.1 - 5.9e-91 305.8 36.0 5.9e-91 305.8 36.0 1.4 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) HHH_8 PF14716.6 CEP11297.1 - 0.0083 16.5 3.4 0.039 14.3 3.4 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain AKNA PF12443.8 CEP11297.1 - 3 8.5 10.4 0.14 12.9 3.2 2.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor SERTA PF06031.13 CEP11298.1 - 0.024 14.3 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 SERTA motif PRY PF13765.6 CEP11299.1 - 5.8 6.6 5.9 0.69 9.6 0.3 2.4 3 0 0 3 3 3 0 SPRY-associated domain Peptidase_S9 PF00326.21 CEP11301.1 - 5.6e-44 150.1 0.0 8.6e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CEP11301.1 - 4.2e-09 36.3 0.0 9.1e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 CEP11301.1 - 4.4e-05 23.5 0.0 0.002 18.1 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 CEP11301.1 - 0.0001 21.7 0.1 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CEP11301.1 - 0.00014 21.8 0.3 0.0035 17.2 0.3 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 CEP11301.1 - 0.0012 17.6 0.2 0.017 13.8 0.2 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 CEP11301.1 - 0.0012 18.6 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 CEP11301.1 - 0.018 14.7 0.0 0.21 11.1 0.0 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CEP11301.1 - 0.029 14.0 0.2 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF829 PF05705.14 CEP11301.1 - 0.034 14.0 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.10 CEP11301.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein PD40 PF07676.12 CEP11301.1 - 0.21 11.5 1.4 2.9 7.9 0.5 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HLH PF00010.26 CEP11302.1 - 6.7e-11 42.0 0.5 2.3e-10 40.3 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_7 PF02796.15 CEP11302.1 - 1.5e-06 28.2 0.6 2.5e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 CEP11302.1 - 0.00057 19.9 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.6 CEP11302.1 - 0.00065 19.7 0.0 0.014 15.4 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix MobC PF05713.11 CEP11302.1 - 0.0019 18.6 0.0 0.0051 17.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) TrmB PF01978.19 CEP11302.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CEP11302.1 - 0.044 13.6 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 CEP11302.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CEP11302.1 - 0.056 13.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 CEP11302.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Mor PF08765.11 CEP11302.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family Nucleo_P87 PF07267.11 CEP11302.1 - 3.9 6.2 4.5 33 3.1 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HEAT PF02985.22 CEP11303.1 - 4.9e-10 38.8 12.4 0.75 10.2 0.1 8.4 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 CEP11303.1 - 7e-09 36.0 0.7 0.035 14.5 0.0 5.1 4 1 2 6 6 6 3 HEAT repeats Cohesin_HEAT PF12765.7 CEP11303.1 - 9.8e-06 25.8 0.3 22 5.5 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 CEP11303.1 - 2.3e-05 24.5 0.3 0.14 12.4 0.0 4.1 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 CEP11303.1 - 0.00071 19.6 11.4 0.14 12.2 0.3 6.1 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 CEP11303.1 - 0.026 13.8 0.0 0.026 13.8 0.0 4.3 1 1 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 CEP11303.1 - 0.065 13.8 2.5 0.27 11.8 0.3 3.5 3 1 0 3 3 3 0 HEAT-like repeat Mic1 PF07035.12 CEP11303.1 - 0.072 12.8 1.4 0.23 11.2 0.3 2.6 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like RasGEF_N_2 PF14663.6 CEP11303.1 - 3.4 8.1 9.3 15 6.0 0.2 4.9 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Forkhead PF00250.18 CEP11304.1 - 1.2e-33 115.2 0.3 2.2e-33 114.3 0.3 1.5 1 0 0 1 1 1 1 Forkhead domain 2OG-FeII_Oxy_3 PF13640.6 CEP11305.1 - 1.1e-11 45.5 0.1 2.1e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 CEP11305.1 - 0.0038 16.4 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 CEP11305.1 - 0.0043 17.5 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DDE_5 PF13546.6 CEP11305.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease AGTRAP PF06396.11 CEP11306.1 - 8.2e-07 28.9 0.0 1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) GTP_EFTU PF00009.27 CEP11307.1 - 7e-55 185.6 0.3 2.4e-54 183.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP11307.1 - 9.6e-36 122.5 0.1 6.6e-35 119.8 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEP11307.1 - 1.1e-13 51.4 0.6 1.1e-13 51.4 0.6 2.7 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEP11307.1 - 0.00035 20.6 0.0 0.015 15.3 0.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2011 PF09428.10 CEP11307.1 - 0.058 13.6 0.6 0.18 12.0 0.1 2.2 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Dynamin_N PF00350.23 CEP11307.1 - 0.059 13.4 0.9 40 4.2 0.1 3.4 3 0 0 3 3 3 0 Dynamin family MecA PF05389.12 CEP11307.1 - 0.071 12.7 7.0 0.13 11.9 7.0 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) NIF3 PF01784.18 CEP11307.1 - 0.092 12.4 0.0 0.77 9.3 0.0 2.2 1 1 1 2 2 2 0 NIF3 (NGG1p interacting factor 3) HEAT_2 PF13646.6 CEP11308.1 - 1.6e-27 95.7 0.2 2.9e-12 46.8 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 CEP11308.1 - 8e-19 66.4 0.0 0.00017 21.9 0.1 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 CEP11308.1 - 4.8e-05 23.8 0.2 10 6.7 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 CEP11308.1 - 5.9e-05 23.0 1.1 16 6.1 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat DUF3248 PF11609.8 CEP11308.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DUF4451 PF14616.6 CEP11309.1 - 6.1e-13 49.0 0.4 1.7e-12 47.6 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Acetyltransf_1 PF00583.25 CEP11309.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3614 PF12267.8 CEP11309.1 - 0.19 12.2 2.3 0.54 10.7 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) WD40 PF00400.32 CEP11310.1 - 3.5e-41 138.4 22.6 2.3e-06 28.2 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CEP11310.1 - 8.3e-12 44.5 7.7 0.035 12.8 0.0 5.8 3 2 2 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 CEP11310.1 - 3.9e-10 39.5 2.1 7.6e-10 38.5 2.1 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CEP11310.1 - 6.7e-09 35.9 1.7 0.67 10.3 0.0 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CEP11310.1 - 5.3e-07 29.4 1.3 1.2e-06 28.2 1.3 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CEP11310.1 - 3.4e-06 26.6 0.4 0.012 14.9 0.1 2.6 1 1 0 1 1 1 1 WD40-like domain F-box_4 PF15966.5 CEP11310.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 CEP11310.1 - 2.3e-05 24.1 0.0 0.042 13.4 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 CEP11310.1 - 0.00036 19.6 1.0 6.7 5.5 0.0 4.1 1 1 2 4 4 4 3 Partner and localizer of BRCA2 WD40 domain PRANC PF09372.10 CEP11310.1 - 0.0031 17.8 0.3 0.0095 16.2 0.3 1.8 1 0 0 1 1 1 1 PRANC domain eIF2A PF08662.11 CEP11310.1 - 0.012 15.5 0.1 0.084 12.7 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP11310.1 - 0.014 14.4 4.2 1 8.2 0.1 3.8 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4476 PF14771.6 CEP11310.1 - 0.089 13.1 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) EPL1 PF10513.9 CEP11311.1 - 3.4e-23 82.8 2.5 3.4e-23 82.8 2.5 3.8 2 1 1 3 3 3 1 Enhancer of polycomb-like Glyco_hydro_18 PF00704.28 CEP11312.1 - 6.5e-26 91.8 2.3 1.3e-25 90.8 2.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CEP11312.1 - 1.8e-14 53.4 23.4 1.8e-14 53.4 23.4 3.3 2 1 1 3 3 3 1 Carbohydrate binding domain (family 19) DUF5462 PF17547.2 CEP11314.1 - 0.018 14.4 0.0 0.88 8.9 0.0 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5462) Sugar_tr PF00083.24 CEP11315.1 - 7.1e-116 387.7 22.2 9.5e-116 387.3 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP11315.1 - 9.4e-26 90.6 40.1 1.3e-21 76.9 18.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ_C PF01556.18 CEP11316.1 - 2.5e-37 128.2 0.4 3.5e-37 127.8 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP11316.1 - 8.6e-27 93.1 3.9 1.4e-26 92.3 3.9 1.4 1 0 0 1 1 1 1 DnaJ domain Sad1_UNC PF07738.13 CEP11317.1 - 7.3e-32 110.2 0.2 1.6e-31 109.0 0.2 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal HCNGP PF07818.13 CEP11317.1 - 3e-27 95.1 2.2 9.1e-27 93.6 0.0 3.1 2 0 0 2 2 2 1 HCNGP-like protein Muskelin_N PF06588.11 CEP11317.1 - 0.0013 18.7 0.2 0.0032 17.4 0.2 1.6 1 0 0 1 1 1 1 Muskelin N-terminus DUF2142 PF09913.9 CEP11317.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) NAD_kinase PF01513.21 CEP11318.1 - 4.3e-61 206.7 0.0 6.9e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Ras PF00071.22 CEP11319.1 - 1.5e-67 226.2 0.1 1.9e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP11319.1 - 1.1e-34 119.2 0.0 1.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP11319.1 - 3.8e-15 55.8 0.0 4.9e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP11319.1 - 3.7e-06 26.6 0.2 9.9e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP11319.1 - 4.9e-05 22.8 0.0 6.1e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEP11319.1 - 5.1e-05 22.8 0.1 6.6e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEP11319.1 - 0.00024 21.1 0.1 0.00056 20.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP11319.1 - 0.00072 19.5 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CEP11319.1 - 0.011 15.3 0.1 0.16 11.5 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 CEP11319.1 - 0.031 14.7 0.1 0.083 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEP11319.1 - 0.045 13.5 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CEP11319.1 - 0.053 12.6 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain GDP_Man_Dehyd PF16363.5 CEP11320.1 - 2.9e-59 201.1 0.0 4.7e-59 200.4 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP11320.1 - 2.8e-48 164.5 0.0 3.7e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP11320.1 - 2.3e-12 46.5 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEP11320.1 - 1.3e-09 37.7 0.0 1.7e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CEP11320.1 - 1.5e-08 34.1 0.0 2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEP11320.1 - 2.7e-08 33.3 0.1 2e-05 23.9 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 CEP11320.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TMEM131_like PF12371.8 CEP11320.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 131-like Cyt-b5 PF00173.28 CEP11321.1 - 6.6e-11 42.2 0.0 8.4e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5442 PF17514.2 CEP11322.1 - 0.085 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5442) FHA PF00498.26 CEP11323.1 - 3.7e-15 56.0 0.2 6.2e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CEP11323.1 - 8.7e-12 44.6 7.9 1.7e-11 43.6 7.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEP11323.1 - 1.5e-09 38.0 7.8 2.5e-09 37.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP11323.1 - 2.1e-05 24.3 9.5 4e-05 23.4 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP11323.1 - 8.1e-05 22.4 7.4 0.00015 21.5 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 CEP11323.1 - 0.00015 22.0 0.1 0.00049 20.4 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 CEP11323.1 - 0.00047 20.1 6.8 0.00094 19.1 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEP11323.1 - 0.0032 17.7 8.4 0.0083 16.4 8.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain PHD PF00628.29 CEP11323.1 - 0.0096 15.8 3.5 0.017 15.0 3.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 CEP11323.1 - 0.024 14.7 1.6 0.046 13.8 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CEP11323.1 - 0.053 13.4 4.8 0.12 12.2 4.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEP11323.1 - 0.084 12.9 10.8 0.18 11.9 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Mit_ribos_Mrp51 PF11709.8 CEP11324.1 - 1.7e-16 60.8 7.8 1.7e-10 41.1 5.9 3.9 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit RCC1 PF00415.18 CEP11325.1 - 1.9e-25 89.2 1.2 2e-08 34.7 0.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEP11325.1 - 3.7e-13 48.9 18.3 2.5e-09 36.7 1.7 5.5 5 1 1 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_59M PF17387.2 CEP11325.1 - 0.022 14.9 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 central domain RWD PF05773.22 CEP11326.1 - 5.9e-22 78.1 5.0 1.2e-21 77.1 5.0 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CEP11326.1 - 8.8e-08 32.5 8.4 2.7e-07 31.0 8.2 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF445 PF04286.12 CEP11326.1 - 0.033 14.0 3.1 0.039 13.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RNase_H2_suC PF08615.11 CEP11326.1 - 0.095 12.9 2.6 0.22 11.7 2.6 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PK PF00224.21 CEP11327.1 - 7.2e-166 551.3 2.4 9.1e-166 551.0 2.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CEP11327.1 - 1.3e-27 96.4 0.0 3.7e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEP11327.1 - 3.8e-05 22.9 0.5 0.00011 21.4 0.4 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CEP11327.1 - 0.022 13.8 0.1 0.29 10.1 0.0 2.4 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 CEP11327.1 - 0.088 12.2 0.0 0.21 11.0 0.1 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) TPP_enzyme_N PF02776.18 CEP11327.1 - 0.15 11.7 0.3 3.8 7.1 0.0 2.6 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain GTP_EFTU PF00009.27 CEP11328.1 - 3.7e-55 186.5 0.1 9.4e-55 185.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP11328.1 - 6.4e-36 123.1 0.1 3.3e-35 120.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEP11328.1 - 6.1e-14 52.2 0.6 6.1e-14 52.2 0.6 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEP11328.1 - 0.00031 20.8 0.3 0.0082 16.2 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.18 CEP11328.1 - 0.038 13.6 0.0 0.45 10.1 0.0 2.2 1 1 0 2 2 2 0 NIF3 (NGG1p interacting factor 3) RasGEF PF00617.19 CEP11329.1 - 8.2e-53 179.2 1.4 6.3e-52 176.3 0.2 2.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEP11329.1 - 5.8e-17 61.8 0.2 5.8e-17 61.8 0.2 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 CEP11329.1 - 7.7e-09 35.0 0.1 2.7e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CEP11329.1 - 4.7e-08 32.6 0.1 1.1e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP11329.1 - 5.2e-05 23.0 0.4 0.00011 21.9 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain Remorin_C PF03763.13 CEP11329.1 - 0.077 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Remorin, C-terminal region DUF4570 PF15134.6 CEP11329.1 - 0.25 11.3 3.1 0.29 11.2 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Chitin_synth_1 PF01644.17 CEP11330.1 - 2.6e-72 242.1 0.0 4e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEP11330.1 - 1e-31 108.6 0.1 2.5e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEP11330.1 - 2.1e-23 82.8 2.6 1e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP11330.1 - 0.00016 21.7 15.9 0.0025 17.7 15.9 2.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP11330.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.20 CEP11331.1 - 1.5e-10 41.2 0.0 5.6e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP11331.1 - 4.7e-06 26.0 0.0 7.6e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP11331.1 - 0.0013 19.4 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CEP11331.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Arrestin_N PF00339.29 CEP11332.1 - 5.1e-09 36.3 0.0 2.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP11332.1 - 0.00069 20.1 0.2 0.0013 19.2 0.2 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain GDP_Man_Dehyd PF16363.5 CEP11333.1 - 4.8e-66 223.4 0.2 3e-65 220.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP11333.1 - 5.5e-48 163.5 0.7 3.7e-47 160.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CEP11333.1 - 2.4e-15 56.4 0.0 2.4e-15 56.4 0.0 1.8 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 CEP11333.1 - 7.7e-15 54.8 0.3 2e-13 50.2 0.3 2.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CEP11333.1 - 1.2e-14 54.0 0.1 1.2e-14 54.0 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CEP11333.1 - 5.7e-14 51.9 0.0 8.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CEP11333.1 - 0.00022 21.2 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAT PF04768.13 CEP11334.1 - 4.9e-40 137.0 0.4 1.8e-38 131.8 0.4 2.3 1 1 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Extensin-like_C PF06904.12 CEP11334.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus Sel1 PF08238.12 CEP11335.1 - 7.9e-14 51.8 21.8 2e-07 31.4 0.5 7.8 8 0 0 8 8 8 4 Sel1 repeat AAA PF00004.29 CEP11336.1 - 3.8e-15 56.5 0.0 8.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 CEP11336.1 - 1.1e-09 38.3 0.6 4.2e-09 36.4 0.6 2.0 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 CEP11336.1 - 2.2e-09 38.0 0.0 9e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP11336.1 - 3.4e-09 37.1 0.1 1.6e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CEP11336.1 - 1e-05 25.0 0.0 0.00016 21.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CEP11336.1 - 3.6e-05 24.1 0.3 0.00011 22.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 CEP11336.1 - 0.00062 19.7 1.1 0.0015 18.4 0.0 2.3 3 0 0 3 3 2 1 CDC6, C terminal winged helix domain TIMELESS_C PF05029.13 CEP11336.1 - 0.00067 18.9 1.9 0.00084 18.6 1.9 1.2 1 0 0 1 1 1 1 Timeless protein C terminal region AAA_11 PF13086.6 CEP11336.1 - 0.0018 18.1 0.1 0.0018 18.1 0.1 2.9 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CEP11336.1 - 0.014 15.3 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CEP11336.1 - 0.017 15.2 0.0 0.16 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP11336.1 - 0.026 14.3 0.3 0.13 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CEP11336.1 - 0.052 12.8 2.9 0.59 9.3 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain AAA_assoc_2 PF16193.5 CEP11336.1 - 0.06 13.7 1.0 1.8 9.0 0.1 2.9 2 0 0 2 2 2 0 AAA C-terminal domain ATPase PF06745.13 CEP11336.1 - 0.065 12.6 0.4 0.17 11.2 0.4 1.7 1 1 0 1 1 1 0 KaiC AAA_18 PF13238.6 CEP11336.1 - 0.089 13.3 0.0 5.1 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 CEP11336.1 - 0.13 10.8 6.4 0.22 10.0 6.4 1.4 1 0 0 1 1 1 0 Macoilin family ResIII PF04851.15 CEP11336.1 - 0.13 12.3 5.1 0.073 13.1 0.4 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CEP11336.1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.4 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DUF4637 PF15470.6 CEP11336.1 - 2.7 7.7 9.8 6.3 6.5 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4614 PF15391.6 CEP11336.1 - 3.8 7.5 16.6 0.43 10.6 11.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) NOA36 PF06524.12 CEP11336.1 - 7.1 5.8 8.3 12 5.1 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 CEP11336.1 - 8.1 4.6 13.3 15 3.8 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C12 PF01088.21 CEP11337.1 - 5.1e-60 202.8 0.0 1.1e-59 201.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CEP11337.1 - 1.3e-15 57.0 4.0 2.7e-15 56.0 4.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med9 PF07544.13 CEP11337.1 - 0.032 14.3 3.1 6.7 6.9 1.4 3.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HAT_KAT11 PF08214.11 CEP11339.1 - 4.8e-36 124.8 0.1 6.6e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF1168 PF06658.12 CEP11340.1 - 0.16 11.8 5.9 0.6 9.9 5.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PEN-2 PF10251.9 CEP11342.1 - 0.094 13.1 1.4 0.17 12.3 1.4 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase AMPK1_CBM PF16561.5 CEP11343.1 - 2.2e-19 69.4 1.0 4.1e-19 68.6 1.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Rad1 PF02144.16 CEP11343.1 - 0.0031 16.6 0.2 0.02 13.9 0.2 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rhodanese PF00581.20 CEP11344.1 - 2e-13 50.8 0.1 6.7e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Lactamase_B PF00753.27 CEP11344.1 - 1e-10 42.0 2.7 2.1e-09 37.6 2.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP11344.1 - 0.0032 17.0 0.1 0.0071 15.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PCI PF01399.27 CEP11345.1 - 9.3e-20 71.1 2.0 7.7e-19 68.2 0.2 2.6 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CEP11345.1 - 2.1e-13 50.1 7.8 7.1e-13 48.4 7.8 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Symplekin_C PF12295.8 CEP11345.1 - 0.51 10.4 7.3 1 9.4 2.6 3.3 1 1 2 3 3 3 0 Symplekin tight junction protein C terminal Exo_endo_phos PF03372.23 CEP11346.1 - 5.8e-19 68.5 0.0 5.8e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CEP11346.1 - 2.3e-10 40.6 15.8 1.6e-07 31.5 1.5 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP11346.1 - 1.8e-09 37.2 8.2 1e-05 25.2 4.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CEP11346.1 - 0.5 11.1 8.0 4.1 8.3 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat TFIIA PF03153.13 CEP11346.1 - 4 7.3 20.0 6.1 6.7 20.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DFP PF04127.15 CEP11347.1 - 6e-19 68.6 0.0 4.3e-11 43.0 0.0 2.2 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein TipAS PF07739.13 CEP11347.1 - 0.088 13.4 0.5 0.18 12.4 0.1 1.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Peptidase_M9_N PF08453.10 CEP11347.1 - 0.22 11.2 1.4 5.4 6.7 0.1 2.4 1 1 1 2 2 2 0 Peptidase family M9 N-terminal Zn_clus PF00172.18 CEP11348.1 - 5.6e-05 23.2 13.4 0.0001 22.3 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_Cas02710 PF09670.10 CEP11348.1 - 0.16 10.7 1.4 9.1 5.0 0.1 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas02710) POP1 PF06978.11 CEP11349.1 - 2.2e-42 145.4 15.0 7.5e-23 81.6 6.3 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CEP11349.1 - 5.5e-29 100.4 0.0 2.1e-28 98.5 0.0 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 CEP11349.1 - 1.1e-06 28.2 0.0 0.037 13.4 0.0 2.9 2 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain Glycos_transf_2 PF00535.26 CEP11350.1 - 1.9e-24 86.3 0.0 2.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEP11350.1 - 2.5e-08 34.1 0.0 3.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CEP11350.1 - 0.0048 16.4 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MutL_C PF08676.11 CEP11351.1 - 1.7e-25 89.5 0.0 4.5e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CEP11351.1 - 8.2e-23 80.3 1.9 1.4e-21 76.4 0.5 2.8 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEP11351.1 - 1.1e-11 44.7 0.0 1.1e-11 44.7 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEP11351.1 - 3e-05 24.5 0.0 0.00012 22.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4724 PF15852.5 CEP11351.1 - 0.041 14.3 2.7 0.08 13.4 1.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4724) Fe_dep_repr_C PF02742.15 CEP11351.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Prenyltrans PF00432.21 CEP11352.1 - 4.5e-27 93.5 0.4 3e-06 26.8 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat F-box-like PF12937.7 CEP11353.1 - 2.2e-08 33.8 2.2 2.2e-08 33.8 2.2 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 CEP11353.1 - 1.1e-07 32.0 14.7 0.018 15.4 0.4 4.9 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) F-box PF00646.33 CEP11353.1 - 1.1e-06 28.3 4.4 2.1e-06 27.5 2.5 2.5 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 CEP11353.1 - 0.017 15.1 17.2 0.12 12.5 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich repeat TPR_19 PF14559.6 CEP11353.1 - 0.037 14.5 0.0 0.16 12.5 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP11353.1 - 0.094 13.0 2.3 0.28 11.4 0.9 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FOXP-CC PF16159.5 CEP11354.1 - 0.00074 20.1 9.5 0.0051 17.4 1.1 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 CEP11354.1 - 0.0027 18.1 8.7 0.046 14.2 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type BAF250_C PF12031.8 CEP11354.1 - 0.012 14.9 0.1 0.026 13.8 0.1 1.6 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa zf-C2H2_aberr PF17017.5 CEP11354.1 - 0.069 13.3 1.8 0.17 12.0 1.8 1.6 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CEP11354.1 - 1.3 10.1 10.1 1.4 10.0 0.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DHHC PF01529.20 CEP11355.1 - 0.00015 21.9 0.3 0.00025 21.2 0.3 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase Adeno_E3_CR2 PF02439.15 CEP11355.1 - 0.29 10.9 2.4 0.55 10.0 2.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LIAS_N PF16881.5 CEP11356.1 - 0.12 12.8 2.7 0.19 12.2 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family DDE_3 PF13358.6 CEP11357.1 - 2.5e-19 69.4 0.0 3.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease NB-ARC PF00931.22 CEP11357.1 - 0.072 12.3 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DDE_Tnp_ISAZ013 PF07592.11 CEP11357.1 - 0.15 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF4240 PF14024.6 CEP11357.1 - 0.17 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) DDE_3 PF13358.6 CEP11359.1 - 6e-22 78.0 0.0 4.6e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease NB-ARC PF00931.22 CEP11359.1 - 0.18 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Ion_trans PF00520.31 CEP11360.1 - 1.2e-135 450.4 78.7 3e-40 138.0 12.0 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CEP11360.1 - 0.0027 17.4 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 CEP11360.1 - 0.019 15.4 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CEP11360.1 - 0.034 14.1 0.1 0.2 11.7 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CEP11360.1 - 0.038 13.6 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 EF hand SSB PF00436.25 CEP11361.1 - 6.8e-13 48.6 0.0 2.2e-10 40.5 0.1 2.1 2 0 0 2 2 2 2 Single-strand binding protein family Bac_export_3 PF01313.19 CEP11362.1 - 0.048 13.6 0.4 0.048 13.6 0.4 2.3 3 0 0 3 3 3 0 Bacterial export proteins, family 3 SieB PF14163.6 CEP11362.1 - 1.1 8.7 6.7 5.4 6.5 1.4 2.5 2 0 0 2 2 2 0 Super-infection exclusion protein B Kinesin PF00225.23 CEP11363.1 - 1.2e-93 313.7 0.5 1.2e-93 313.7 0.5 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP11363.1 - 1.2e-14 54.5 5.9 4.3e-09 36.5 0.0 3.6 2 1 1 3 3 3 2 Microtubule binding SAM_1 PF00536.30 CEP11363.1 - 0.012 16.0 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PA26 PF04636.13 CEP11363.1 - 1 8.2 11.2 0.11 11.4 0.7 2.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) WD40 PF00400.32 CEP11365.1 - 2.7e-37 126.1 15.0 5.8e-07 30.1 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 CEP11365.1 - 9.4e-11 41.0 2.9 0.067 11.8 0.1 5.1 3 1 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEP11365.1 - 1.5e-10 41.2 1.4 0.93 9.8 0.1 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP11365.1 - 3.6e-10 39.6 0.2 3.6e-10 39.6 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP11365.1 - 4.5e-08 32.8 0.1 1.3e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CEP11365.1 - 4.1e-07 29.6 0.7 0.0026 17.1 0.1 3.3 1 1 2 3 3 3 2 WD40-like domain F-box_4 PF15966.5 CEP11365.1 - 0.00025 20.9 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 F-box PQQ_2 PF13360.6 CEP11365.1 - 0.0085 15.7 0.5 2.7 7.5 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 CEP11365.1 - 0.018 14.1 3.1 5.1 6.0 0.3 3.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 120_Rick_ant PF12574.8 CEP11365.1 - 0.053 12.7 0.2 0.17 11.1 0.1 1.8 2 1 0 2 2 2 0 120 KDa Rickettsia surface antigen CDtoxinA PF03498.14 CEP11365.1 - 0.14 11.8 0.7 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Retrotrans_gag PF03732.17 CEP11366.1 - 1e-06 28.9 0.3 2.6e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1473 PF07341.11 CEP11366.1 - 0.018 14.8 1.0 0.71 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1473) Ribosomal_S7 PF00177.21 CEP11367.1 - 3.3e-37 127.4 0.9 4.1e-37 127.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Oxysterol_BP PF01237.18 CEP11368.1 - 9.9e-88 294.5 6.4 1.5e-85 287.3 6.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein NicO PF03824.16 CEP11369.1 - 4e-81 272.5 15.5 5.3e-81 272.1 15.5 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein MHYT PF03707.16 CEP11369.1 - 0.062 13.5 0.5 0.062 13.5 0.5 4.1 6 0 0 6 6 6 0 Bacterial signalling protein N terminal repeat BIV_Env PF05858.12 CEP11369.1 - 0.073 11.3 1.8 0.1 10.8 1.0 1.7 1 1 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) DUF3810 PF12725.7 CEP11369.1 - 2.3 7.5 6.6 1.5 8.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) E1_DerP2_DerF2 PF02221.15 CEP11370.1 - 4.9e-13 49.7 0.1 5.9e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 ML domain HLH PF00010.26 CEP11371.1 - 1e-14 54.2 0.5 2.4e-14 53.0 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4468 PF14730.6 CEP11371.1 - 0.058 13.7 0.3 0.15 12.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold CDT1 PF08839.11 CEP11371.1 - 0.31 11.3 3.9 0.27 11.5 1.8 1.8 1 1 1 2 2 2 0 DNA replication factor CDT1 like HSP70 PF00012.20 CEP11371.1 - 5.6 5.0 7.2 7.7 4.6 7.2 1.1 1 0 0 1 1 1 0 Hsp70 protein FSH1 PF03959.13 CEP11372.1 - 6.4e-58 195.9 0.0 7.2e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 CEP11372.1 - 0.0036 17.5 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 CEP11372.1 - 0.015 14.6 0.2 0.26 10.5 0.0 2.6 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP11372.1 - 0.035 13.8 0.0 0.43 10.2 0.0 2.3 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CEP11372.1 - 0.042 13.7 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CEP11372.1 - 0.083 12.5 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Nup35_RRM PF05172.13 CEP11373.1 - 3.1e-14 52.7 0.2 1e-13 51.1 0.2 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CEP11373.1 - 6.2e-08 32.5 0.0 9.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 CEP11374.1 - 5.8e-36 122.3 5.1 8.4e-13 48.1 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP11374.1 - 0.016 14.3 1.2 0.15 11.1 0.1 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease MFS_1 PF07690.16 CEP11375.1 - 4.9e-35 121.1 72.5 4.2e-30 104.9 38.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GIT_SHD PF08518.11 CEP11376.1 - 1.3e-26 91.9 2.7 1.4e-13 50.2 0.3 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ANAPC8 PF04049.13 CEP11376.1 - 4.3e-22 78.7 0.3 4.3e-22 78.7 0.3 2.5 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 CEP11376.1 - 5.1e-21 73.5 18.9 5.5e-05 22.8 1.8 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP11376.1 - 2.2e-18 64.8 18.6 0.002 18.1 0.3 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11376.1 - 5.1e-14 52.6 9.6 6.6e-10 39.5 0.5 6.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11376.1 - 1.4e-13 49.9 16.5 0.0022 18.1 0.0 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11376.1 - 7.9e-11 42.1 15.4 1.2e-05 25.5 0.3 5.7 2 1 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEP11376.1 - 9.4e-09 35.4 16.0 0.0046 17.7 0.5 7.6 4 1 4 8 8 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11376.1 - 8.1e-08 31.8 16.0 4.1e-06 26.4 0.4 4.9 3 2 2 5 5 4 2 TPR repeat TPR_19 PF14559.6 CEP11376.1 - 1.8e-07 31.5 9.3 0.0018 18.8 0.6 5.7 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP11376.1 - 1.7e-05 24.5 14.2 0.38 10.9 0.3 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11376.1 - 2.3e-05 24.4 6.0 0.082 13.3 0.4 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat APG6_N PF17675.1 CEP11376.1 - 0.001 19.6 11.1 0.001 19.6 11.1 3.0 2 0 0 2 2 1 1 Apg6 coiled-coil region ADIP PF11559.8 CEP11376.1 - 0.0065 16.6 11.9 0.016 15.3 8.9 2.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding VBS PF08913.10 CEP11376.1 - 0.013 15.9 4.9 0.46 10.9 0.6 3.5 3 0 0 3 3 3 0 Vinculin Binding Site ANAPC3 PF12895.7 CEP11376.1 - 0.013 15.7 2.0 0.013 15.7 2.0 4.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEP11376.1 - 0.015 15.9 20.0 25 5.8 0.0 7.5 7 0 0 7 7 6 0 Tetratricopeptide repeat GIT1_C PF12205.8 CEP11376.1 - 0.036 14.2 0.1 0.036 14.2 0.1 3.1 3 0 0 3 3 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Tropomyosin PF00261.20 CEP11376.1 - 0.047 13.1 13.8 0.11 11.8 13.8 1.6 1 0 0 1 1 1 0 Tropomyosin MapZ_EC1 PF18041.1 CEP11376.1 - 0.062 13.5 7.7 0.26 11.5 6.2 2.7 2 0 0 2 2 2 0 MapZ extracellular domain 1 TPR_10 PF13374.6 CEP11376.1 - 0.074 12.9 10.7 25 4.9 0.3 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEP11376.1 - 0.085 13.0 1.9 5.6 7.2 0.5 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat FUSC PF04632.12 CEP11376.1 - 0.15 10.5 8.1 0.13 10.8 0.1 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family bZIP_1 PF00170.21 CEP11376.1 - 0.15 12.2 8.8 0.62 10.2 4.2 3.3 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CEP11376.1 - 0.2 12.1 15.0 0.89 10.0 5.5 3.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 CEP11376.1 - 0.22 10.8 13.5 0.72 9.1 12.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3410 PF11890.8 CEP11376.1 - 0.22 11.3 2.2 0.59 10.0 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Med30 PF11315.8 CEP11376.1 - 0.33 11.1 9.8 2.2 8.5 9.8 2.5 1 0 0 1 1 1 0 Mediator complex subunit 30 Cep57_MT_bd PF06657.13 CEP11376.1 - 0.37 11.3 6.8 1 9.8 4.8 2.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.8 CEP11376.1 - 0.77 9.8 14.1 0.14 12.1 5.8 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 CEP11376.1 - 0.77 9.9 7.7 0.33 11.1 2.5 3.0 2 0 0 2 2 2 0 Swi5 CENP-F_leu_zip PF10473.9 CEP11376.1 - 1.4 8.9 14.8 0.42 10.6 7.8 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 CEP11376.1 - 3.1 7.6 16.1 4.8 7.0 7.2 3.2 2 1 1 3 3 2 0 Septum formation initiator BTAD PF03704.17 CEP11376.1 - 3.4 8.1 10.2 6.1 7.3 1.2 3.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain ERM PF00769.19 CEP11376.1 - 3.8 7.3 26.5 0.011 15.6 6.8 3.0 3 0 0 3 3 3 0 Ezrin/radixin/moesin family DUF2203 PF09969.9 CEP11376.1 - 4.1 8.1 12.9 4.9 7.9 5.8 4.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Tho2 PF11262.8 CEP11376.1 - 5.5 6.1 19.3 0.13 11.5 10.5 2.7 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Sugar_tr PF00083.24 CEP11377.1 - 1.3e-94 317.7 36.8 8.2e-50 170.0 21.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP11377.1 - 1.2e-20 73.8 55.7 5.2e-18 65.1 28.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Poxvirus_B22R_N PF13169.6 CEP11378.1 - 0.0019 18.7 0.9 0.0027 18.2 0.9 1.3 1 0 0 1 1 1 1 Poxvirus B22R protein N-terminal Vault_2 PF17794.1 CEP11379.1 - 0.11 12.9 0.4 16 5.9 0.1 2.4 2 0 0 2 2 2 0 Major Vault Protein repeat domain Aminotran_3 PF00202.21 CEP11379.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III LRR_4 PF12799.7 CEP11380.1 - 6.6e-31 105.9 53.5 0.00021 21.6 0.3 11.8 7 3 8 15 15 15 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP11380.1 - 1.1e-30 105.2 54.4 2.6e-06 27.1 0.1 10.2 5 3 7 13 13 13 11 Leucine rich repeat LRR_6 PF13516.6 CEP11380.1 - 1.4e-10 40.3 39.4 0.011 15.8 0.1 11.6 13 0 0 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.6 CEP11380.1 - 4.4e-09 36.1 20.7 0.013 15.0 0.4 6.1 2 2 6 8 8 8 6 Leucine-rich repeat LRR_1 PF00560.33 CEP11380.1 - 1e-07 31.5 40.7 1.6 9.6 1.1 14.1 14 3 0 14 14 14 2 Leucine Rich Repeat MecA PF05389.12 CEP11380.1 - 0.018 14.7 0.6 0.11 12.2 0.0 2.3 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) RsmF_methylt_CI PF17126.5 CEP11380.1 - 0.018 15.1 0.1 0.98 9.5 0.0 3.3 3 0 0 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain EzrA PF06160.12 CEP11380.1 - 0.077 11.2 8.2 0.11 10.6 0.0 3.4 3 1 1 4 4 4 0 Septation ring formation regulator, EzrA LRR_3 PF07725.12 CEP11380.1 - 4.7 7.2 12.7 12 6.0 0.3 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat DPPIV_N PF00930.21 CEP11381.1 - 4.8e-98 328.2 6.1 4.8e-98 328.2 6.1 1.4 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CEP11381.1 - 6.1e-54 182.7 2.3 1.1e-53 181.8 2.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CEP11381.1 - 2.4e-05 24.1 3.4 3.7e-05 23.5 1.4 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CEP11381.1 - 0.0006 20.5 0.5 0.0033 18.1 0.3 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CEP11381.1 - 0.0017 17.9 0.0 0.0072 15.9 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CEP11381.1 - 0.0019 18.0 0.1 0.18 11.5 0.1 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 CEP11381.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 CEP11381.1 - 0.0025 17.8 0.1 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 CEP11381.1 - 0.0026 17.1 0.3 0.035 13.4 0.1 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP11381.1 - 0.007 16.0 0.9 0.019 14.6 0.4 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold LIP PF03583.14 CEP11381.1 - 0.036 13.4 0.9 0.072 12.4 0.9 1.4 1 0 0 1 1 1 0 Secretory lipase AXE1 PF05448.12 CEP11381.1 - 0.048 12.3 0.1 0.36 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Alba PF01918.21 CEP11382.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Alba DUF4778 PF16008.5 CEP11382.1 - 0.019 15.1 2.7 0.023 14.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) ERG4_ERG24 PF01222.17 CEP11383.1 - 1.4e-147 491.9 11.9 1.7e-147 491.7 11.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CEP11383.1 - 0.0031 17.1 0.6 0.0031 17.1 0.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Septin PF00735.18 CEP11384.1 - 2.7e-112 374.7 0.0 2.7e-112 374.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEP11384.1 - 2.6e-06 27.5 0.1 7.2e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEP11384.1 - 0.0014 18.7 2.9 1.2 9.2 0.0 3.2 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 CEP11384.1 - 0.013 15.7 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEP11384.1 - 0.014 14.9 0.4 0.1 12.2 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CEP11384.1 - 0.029 13.7 0.0 0.083 12.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 CEP11384.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.8 3 1 0 3 3 3 0 RsgA GTPase BCDHK_Adom3 PF10436.9 CEP11386.1 - 7.6e-07 29.1 0.8 2.5e-06 27.4 0.6 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Toprim_3 PF13362.6 CEP11386.1 - 0.1 13.0 0.0 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Toprim domain bZIP_1 PF00170.21 CEP11387.1 - 1.8e-12 47.2 9.1 1.8e-12 47.2 9.1 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP11387.1 - 1.3e-07 31.6 7.6 3.1e-07 30.3 7.6 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 CEP11387.1 - 1.4e-05 25.4 1.3 6.3e-05 23.3 1.3 2.2 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain HALZ PF02183.18 CEP11387.1 - 0.0023 18.1 1.2 0.0045 17.2 1.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_Maf PF03131.17 CEP11387.1 - 0.0045 17.5 4.0 0.0045 17.5 4.0 2.2 2 1 1 3 3 3 1 bZIP Maf transcription factor JIP_LZII PF16471.5 CEP11387.1 - 0.017 15.3 0.3 0.036 14.2 0.3 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ASD2 PF08687.11 CEP11387.1 - 0.032 13.8 6.1 0.044 13.3 6.1 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF2576 PF10845.8 CEP11387.1 - 0.04 13.5 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Ant_C PF05586.11 CEP11387.1 - 0.061 13.9 0.3 0.17 12.5 0.3 1.7 1 0 0 1 1 1 0 Anthrax receptor C-terminus region YabA PF06156.13 CEP11387.1 - 0.21 12.2 4.3 0.16 12.6 2.4 1.8 1 1 1 2 2 2 0 Initiation control protein YabA Phlebovirus_NSM PF07246.11 CEP11387.1 - 0.22 10.9 4.8 0.26 10.6 4.0 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M 2-oxoacid_dh PF00198.23 CEP11388.1 - 6.7e-82 274.4 0.5 9.5e-82 273.9 0.5 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEP11388.1 - 1.2e-17 63.5 1.9 2.7e-17 62.4 1.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 CEP11388.1 - 4.3e-05 23.4 0.6 0.00011 22.1 0.6 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 CEP11388.1 - 0.00099 19.8 0.8 0.79 10.5 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 CEP11388.1 - 0.0034 17.2 1.6 0.27 11.1 0.2 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like DUF3614 PF12267.8 CEP11388.1 - 0.015 15.8 0.8 0.25 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) RnfC_N PF13375.6 CEP11388.1 - 0.027 14.4 0.2 0.071 13.1 0.2 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF1473 PF07341.11 CEP11388.1 - 0.051 13.4 0.1 0.18 11.6 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1473) DUF2118 PF09891.9 CEP11388.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RGS12_usC PF16612.5 CEP11388.1 - 1 9.8 10.8 0.13 12.7 5.9 1.9 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 4HBT PF03061.22 CEP11389.1 - 6.5e-08 32.8 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily WD40 PF00400.32 CEP11389.1 - 0.0051 17.6 12.5 0.36 11.8 0.0 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11389.1 - 0.047 14.0 0.0 23 5.4 0.0 4.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain NAPRTase PF04095.16 CEP11390.1 - 1.1e-69 234.7 0.6 1.6e-69 234.1 0.6 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CEP11390.1 - 8.3e-34 116.7 2.4 1.6e-33 115.8 2.4 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Zds_C PF08632.10 CEP11391.1 - 2.6e-17 62.3 0.3 5.7e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term eIF3_p135 PF12807.7 CEP11391.1 - 0.03 14.3 0.3 0.03 14.3 0.3 2.4 2 1 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 SUIM_assoc PF16619.5 CEP11391.1 - 0.71 10.0 23.0 2.4 8.3 0.0 3.6 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 VIT1 PF01988.19 CEP11391.1 - 3.4 7.5 3.8 1.1 9.1 0.3 1.9 2 0 0 2 2 2 0 VIT family Septin PF00735.18 CEP11392.1 - 9.5e-115 382.7 0.5 1.2e-114 382.4 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP11392.1 - 3.8e-09 36.6 0.2 1.4e-08 34.8 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP11392.1 - 3.8e-08 33.4 0.6 1.1e-06 28.7 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CEP11392.1 - 1.7e-06 27.5 0.0 3.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CEP11392.1 - 2.9e-06 27.0 0.2 0.0003 20.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP11392.1 - 4.2e-05 23.0 0.2 0.005 16.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 CEP11392.1 - 9.3e-05 21.7 0.1 0.00018 20.8 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Dynamin_N PF00350.23 CEP11392.1 - 0.00013 22.1 1.5 0.42 10.6 0.8 2.7 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 CEP11392.1 - 0.00027 21.4 0.3 0.0011 19.4 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CEP11392.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Ras PF00071.22 CEP11392.1 - 0.0023 17.5 0.1 0.0078 15.8 0.0 1.9 2 1 0 2 2 2 1 Ras family Roc PF08477.13 CEP11392.1 - 0.0025 18.0 0.0 0.0063 16.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CEP11392.1 - 0.0047 16.5 0.6 0.026 14.0 0.6 2.2 1 1 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CEP11392.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CEP11392.1 - 0.0076 16.5 0.1 0.015 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 CEP11392.1 - 0.011 14.9 1.6 0.17 11.0 0.5 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 CEP11392.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CEP11392.1 - 0.022 14.8 0.1 0.077 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CEP11392.1 - 0.03 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CEP11392.1 - 0.051 13.3 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.13 CEP11392.1 - 0.062 12.3 0.4 0.15 11.1 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF1542 PF07564.11 CEP11392.1 - 0.086 13.0 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) AAA_24 PF13479.6 CEP11392.1 - 0.12 12.0 0.4 0.45 10.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEP11392.1 - 0.15 12.3 0.4 0.85 9.8 0.4 2.3 1 1 0 1 1 1 0 AAA domain Nnf1 PF03980.14 CEP11394.1 - 0.13 12.7 1.6 0.2 12.0 1.6 1.2 1 0 0 1 1 1 0 Nnf1 zf-H2C2_2 PF13465.6 CEP11395.1 - 5.1e-21 74.1 31.5 2.6e-07 30.8 1.1 5.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CEP11395.1 - 1.9e-17 62.6 41.8 6.4e-06 26.3 0.6 5.8 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP11395.1 - 3.1e-09 36.9 37.8 0.0071 17.1 0.5 5.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP11395.1 - 0.0046 17.2 12.7 0.12 12.7 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEP11395.1 - 0.0051 17.4 15.8 0.68 10.6 0.7 5.0 2 1 3 5 5 5 2 FOXP coiled-coil domain zf-TRAF PF02176.18 CEP11395.1 - 0.0068 17.1 9.6 0.58 10.9 2.1 3.6 1 1 2 3 3 3 2 TRAF-type zinc finger zf-C2H2_8 PF15909.5 CEP11395.1 - 0.011 16.0 11.6 0.013 15.8 1.2 3.4 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CEP11395.1 - 0.043 13.8 16.3 4.2 7.5 0.3 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CEP11395.1 - 0.21 12.0 7.7 0.64 10.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CEP11395.1 - 0.26 11.4 5.9 3 8.0 0.3 3.3 2 2 0 2 2 2 0 Aberrant zinc-finger Erf4 PF10256.9 CEP11396.1 - 0.04 14.0 0.7 0.31 11.1 0.2 2.7 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family UVR PF02151.19 CEP11396.1 - 0.37 10.6 0.0 0.37 10.6 0.0 6.1 6 0 0 6 6 6 0 UvrB/uvrC motif DUF2064 PF09837.9 CEP11396.1 - 0.37 10.6 8.1 1.3 8.9 0.1 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) HTH_23 PF13384.6 CEP11397.1 - 1e-05 25.1 1.9 2e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 CEP11397.1 - 0.00024 20.7 0.0 0.0094 15.6 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 CEP11397.1 - 0.00036 20.5 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 CEP11397.1 - 0.00069 20.2 0.2 0.073 13.7 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP11397.1 - 0.0014 18.0 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 CEP11397.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Crp_2 PF13545.6 CEP11397.1 - 0.0019 18.1 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain PAX PF00292.18 CEP11397.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.6 CEP11397.1 - 0.08 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain 7TMR-DISMED2 PF07696.11 CEP11397.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 FeoC PF09012.10 CEP11397.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF4794 PF16042.5 CEP11398.1 - 0.079 14.0 0.5 0.32 12.0 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4794) KAAG1 PF15354.6 CEP11398.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Kidney-associated antigen 1 Cwf_Cwc_15 PF04889.12 CEP11398.1 - 6.3 6.5 14.3 12 5.6 14.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EBP50_C PF09007.11 CEP11399.1 - 0.0062 17.5 1.4 0.0085 17.1 1.4 1.2 1 0 0 1 1 1 1 EBP50, C-terminal zf-CCHC PF00098.23 CEP11400.1 - 2.1e-06 27.6 3.0 4.2e-06 26.6 3.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CEP11400.1 - 1.1e-05 25.9 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP11400.1 - 8.3e-05 23.1 0.8 0.00018 22.0 0.2 1.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP11400.1 - 0.015 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2845 PF11006.8 CEP11400.1 - 0.024 14.7 1.6 6.1 7.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2845) zf-CCHC_4 PF14392.6 CEP11400.1 - 0.093 12.5 0.5 0.22 11.3 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CEP11400.1 - 0.43 10.3 9.2 0.72 9.6 9.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-3CxxC PF13695.6 CEP11402.1 - 0.033 14.6 1.0 0.056 13.9 0.9 1.7 1 1 0 1 1 1 0 Zinc-binding domain DUF1827 PF08860.10 CEP11402.1 - 2.5 8.4 12.3 9.6 6.5 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1827) DAAD PF18752.1 CEP11402.1 - 6.4 6.5 13.1 7.3 6.3 13.1 1.0 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Phosphoesterase PF04185.14 CEP11404.1 - 6.8e-32 111.0 8.6 1.4e-30 106.7 4.0 2.9 1 1 1 2 2 2 2 Phosphoesterase family Glyco_transf_49 PF13896.6 CEP11405.1 - 9e-43 146.9 0.8 3.2e-33 115.5 0.2 2.7 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan IlvN PF07991.12 CEP11406.1 - 2.4e-45 154.1 0.0 5.8e-45 152.8 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CEP11406.1 - 5.9e-42 143.4 0.0 9.8e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 CEP11406.1 - 0.0041 17.7 0.1 0.042 14.4 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CEP11406.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CEP11406.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aldolase_II PF00596.21 CEP11407.1 - 5.1e-47 160.2 0.0 7.6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain G-patch PF01585.23 CEP11407.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 G-patch domain TPR_2 PF07719.17 CEP11408.1 - 2.7e-45 148.8 41.8 0.00047 20.1 0.1 18.4 19 0 0 19 19 18 10 Tetratricopeptide repeat TPR_1 PF00515.28 CEP11408.1 - 6e-44 146.1 35.5 7.2e-06 25.6 0.1 16.6 17 0 0 17 17 16 8 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11408.1 - 1.5e-29 102.1 31.1 1.3e-06 28.5 0.0 14.2 12 2 3 15 15 14 8 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11408.1 - 2.9e-29 98.8 41.7 4.7e-07 29.5 0.0 15.4 18 0 0 18 18 15 7 Tetratricopeptide repeat TPR_14 PF13428.6 CEP11408.1 - 1.5e-27 93.9 13.6 0.0064 17.2 0.1 15.6 12 2 5 17 17 15 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11408.1 - 5.4e-26 90.9 22.3 0.00032 21.1 0.0 12.2 13 1 1 14 14 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11408.1 - 1.2e-22 78.6 26.1 0.015 15.6 0.0 16.2 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11408.1 - 1.1e-19 70.8 7.0 0.0004 21.0 0.6 10.4 9 1 3 12 12 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11408.1 - 3.2e-15 55.5 26.8 0.008 15.8 0.0 11.9 12 2 2 14 14 12 5 TPR repeat TPR_7 PF13176.6 CEP11408.1 - 5.8e-14 51.0 19.3 0.41 10.8 0.0 11.4 14 0 0 14 14 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEP11408.1 - 3.3e-10 40.0 4.8 0.19 11.9 0.0 7.6 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP11408.1 - 1e-08 34.7 22.9 1.5 8.8 0.1 11.6 13 0 0 13 13 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP11408.1 - 3.7e-06 27.1 15.0 0.021 15.0 0.3 7.2 5 3 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 CEP11408.1 - 0.00067 18.5 0.4 0.076 11.7 0.2 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 CEP11408.1 - 0.0012 19.3 34.2 1.1 10.0 0.1 12.9 16 0 0 16 16 12 1 Tetratricopeptide repeat ChAPs PF09295.10 CEP11408.1 - 0.0025 16.9 5.9 1.6 7.6 0.0 4.8 5 0 0 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 CEP11408.1 - 0.0028 18.1 5.4 27 5.8 0.4 6.2 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 CEP11408.1 - 0.077 13.1 1.9 12 5.9 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 CEP11408.1 - 0.094 13.0 3.8 1.2e+02 3.3 0.1 5.6 5 0 0 5 5 5 0 PPR repeat TPR_20 PF14561.6 CEP11408.1 - 0.096 13.0 1.7 38 4.7 0.0 4.7 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_22 PF18833.1 CEP11408.1 - 0.1 12.8 2.2 0.35 11.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 CEP11408.1 - 0.47 11.2 4.6 14 6.6 0.2 4.8 4 0 0 4 4 4 0 Sel1 repeat Thioredoxin PF00085.20 CEP11409.1 - 2e-19 69.5 0.0 2.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEP11409.1 - 0.00047 20.6 0.0 0.00096 19.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEP11409.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 CEP11409.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 CEP11409.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 CEP11409.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family HTH_29 PF13551.6 CEP11410.1 - 0.00013 21.9 0.1 0.00032 20.7 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CEP11410.1 - 0.033 14.3 0.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 CEP11410.1 - 0.064 13.1 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_40 PF14493.6 CEP11410.1 - 0.09 13.2 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 CEP11410.1 - 0.093 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Radical_SAM_C PF16199.5 CEP11411.1 - 7.1e-33 112.5 0.1 2.2e-32 110.9 0.1 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CEP11411.1 - 3.8e-18 66.4 0.0 1e-17 65.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CEP11411.1 - 3.8e-09 36.8 0.0 7.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP11411.1 - 6.6e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP11411.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP11411.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein KDZ PF18758.1 CEP11412.1 - 7.3e-23 81.3 0.0 1.1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase APC_u14 PF16635.5 CEP11413.1 - 0.011 16.3 2.7 0.013 16.0 2.7 1.2 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr TFR_dimer PF04253.15 CEP11414.1 - 2.6e-31 108.3 0.1 4.9e-31 107.3 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 CEP11414.1 - 4.2e-10 39.5 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 PA domain NAD_binding_1 PF00175.21 CEP11415.1 - 1.1e-31 109.6 0.0 5.6e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEP11415.1 - 3.5e-21 75.4 0.0 1.1e-20 73.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEP11415.1 - 1.2e-07 32.0 0.0 4.2e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEP11415.1 - 0.018 15.2 0.2 0.11 12.7 0.0 2.2 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain TFR_dimer PF04253.15 CEP11416.1 - 1.2e-32 112.5 0.3 2.9e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CEP11416.1 - 2.2e-20 73.2 0.0 3.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEP11416.1 - 7.5e-09 35.5 0.0 1.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 PA domain DHR10 PF18595.1 CEP11416.1 - 0.03 14.4 0.2 0.059 13.4 0.2 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Peptidase_M20 PF01546.28 CEP11416.1 - 0.074 12.7 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 DUF4164 PF13747.6 CEP11416.1 - 0.67 10.3 3.9 0.23 11.8 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Y_phosphatase PF00102.27 CEP11418.1 - 1.4e-61 208.1 1.1 3.1e-61 206.9 1.1 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CEP11418.1 - 3.2e-13 50.1 0.0 2.6e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 CEP11418.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Whi5 PF08528.11 CEP11419.1 - 0.0008 19.0 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Whi5 like CENP-U PF13097.6 CEP11419.1 - 0.072 13.0 1.6 0.1 12.5 0.6 1.7 1 1 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit P_C PF06640.11 CEP11419.1 - 0.13 12.4 1.3 0.25 11.5 1.3 1.4 1 0 0 1 1 1 0 P protein C-terminus MAP65_ASE1 PF03999.12 CEP11419.1 - 1.1 7.8 8.0 1.5 7.4 8.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Npa1 PF11707.8 CEP11420.1 - 8.4e-92 308.1 0.0 3.9e-91 305.9 0.0 2.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CEP11420.1 - 3e-53 180.4 6.1 5.2e-53 179.6 0.5 3.9 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 CEP11420.1 - 0.0015 19.2 3.5 0.0038 17.9 0.0 3.3 4 0 0 4 4 4 1 Creb binding zf-C2H2 PF00096.26 CEP11422.1 - 0.0021 18.4 4.2 0.0021 18.4 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type Cwf_Cwc_15 PF04889.12 CEP11422.1 - 0.68 9.6 6.2 1.3 8.7 6.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2_4 PF13894.6 CEP11422.1 - 0.99 10.4 6.7 0.6 11.1 4.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DHHC PF01529.20 CEP11424.1 - 0.003 17.6 1.1 0.0056 16.8 1.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4469 PF14734.6 CEP11425.1 - 0.013 15.7 0.1 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold CRAL_TRIO PF00650.20 CEP11426.1 - 7.7e-40 136.2 0.1 1.6e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP11426.1 - 1.3e-08 34.9 0.2 3.2e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEP11426.1 - 3.5e-08 33.7 0.0 6.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DDE_Tnp_1_7 PF13843.6 CEP11427.1 - 2.4e-33 115.9 0.1 4.5e-31 108.4 0.0 2.8 1 1 1 2 2 2 2 Transposase IS4 OPT PF03169.15 CEP11428.1 - 1.4e-88 298.2 39.8 1.6e-88 297.9 39.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 CEP11428.1 - 0.00091 19.5 0.1 0.0033 17.7 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) DUF4730 PF15873.5 CEP11428.1 - 0.045 14.0 1.3 2.8 8.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) Halogen_Hydrol PF10112.9 CEP11428.1 - 4.9 7.1 7.7 0.64 10.0 1.0 2.8 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TMEM40 PF15817.5 CEP11428.1 - 8.1 6.2 6.4 3 7.6 0.1 3.5 4 0 0 4 4 4 0 Transmembrane protein 40 family CDC45 PF02724.14 CEP11429.1 - 0.0029 16.0 1.2 0.004 15.5 1.2 1.3 1 0 0 1 1 1 1 CDC45-like protein OrfB_Zn_ribbon PF07282.11 CEP11429.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DDRGK PF09756.9 CEP11429.1 - 0.13 11.8 16.3 0.28 10.8 16.3 1.5 1 0 0 1 1 1 0 DDRGK domain TLP-20 PF06088.11 CEP11429.1 - 4 7.3 6.8 1.7 8.5 3.8 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 CEP11429.1 - 7.5 5.2 5.8 11 4.6 5.8 1.2 1 0 0 1 1 1 0 Presenilin Sacchrp_dh_NADP PF03435.18 CEP11430.1 - 6e-15 55.7 0.0 8.5e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Cpn60_TCP1 PF00118.24 CEP11431.1 - 2.6e-167 557.4 4.8 3.2e-167 557.1 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pept_tRNA_hydro PF01195.19 CEP11432.1 - 5.7e-44 150.1 0.1 6.8e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase NRDE-2 PF08424.10 CEP11433.1 - 8.8e-97 324.1 17.5 2.6e-96 322.6 6.3 3.3 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CEP11433.1 - 5.3e-08 33.0 0.4 1.5 9.8 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11433.1 - 0.00077 19.9 0.7 8.8 6.9 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEP11433.1 - 0.0021 18.0 5.2 1.7 8.7 0.2 5.0 5 0 0 5 5 5 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CEP11433.1 - 0.0047 16.9 1.2 2.1 8.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11433.1 - 0.015 15.6 0.3 0.099 13.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4184 PF13803.6 CEP11433.1 - 0.086 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) TPR_MalT PF17874.1 CEP11433.1 - 1.2 8.4 5.3 1.5 8.1 0.1 2.9 4 0 0 4 4 4 0 MalT-like TPR region TPR_17 PF13431.6 CEP11433.1 - 1.6 9.3 7.5 64 4.3 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HMGL-like PF00682.19 CEP11434.1 - 1.4e-57 195.3 0.0 1.9e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Ssu72 PF04722.13 CEP11436.1 - 4.6e-85 284.0 0.0 5.2e-85 283.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF5530 PF17670.1 CEP11436.1 - 0.084 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5530) GP3_package PF16677.5 CEP11436.1 - 0.097 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 DNA-packaging protein gp3 PITH PF06201.13 CEP11437.1 - 4.3e-37 127.7 7.7 6.5e-37 127.1 7.7 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CEP11437.1 - 3.7e-29 100.7 0.5 9.4e-29 99.4 0.5 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEP11437.1 - 0.0002 21.7 0.3 0.0022 18.4 0.3 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP11437.1 - 0.00039 20.7 0.5 0.0014 18.9 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 CEP11437.1 - 0.0099 15.3 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 CEP11437.1 - 0.0099 15.6 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 CEP11437.1 - 0.053 13.7 0.4 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like UbiA PF01040.18 CEP11438.1 - 4.4e-57 193.3 19.1 5.5e-57 192.9 19.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family TNFR_16_TM PF18422.1 CEP11438.1 - 0.037 14.0 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Mo-nitro_C PF06967.11 CEP11438.1 - 0.14 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus Pkinase PF00069.25 CEP11439.1 - 6.9e-73 245.2 0.0 8.4e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11439.1 - 3.9e-34 118.1 0.0 5.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP11439.1 - 4e-06 26.4 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP11439.1 - 2.3e-05 23.4 0.0 5.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEP11439.1 - 5.6e-05 22.6 0.0 9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEP11439.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Phage_connect_1 PF05135.13 CEP11439.1 - 0.0044 17.5 0.6 0.017 15.6 0.2 2.2 2 1 0 2 2 2 1 Phage gp6-like head-tail connector protein APH PF01636.23 CEP11439.1 - 0.0068 16.4 0.1 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family G-alpha PF00503.20 CEP11440.1 - 4.8e-106 354.9 11.5 4.8e-106 354.9 11.5 1.6 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 CEP11440.1 - 2.5e-15 56.4 0.4 1.4e-10 40.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Rhodanese PF00581.20 CEP11440.1 - 3.9e-09 37.0 0.1 1.6e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Gtr1_RagA PF04670.12 CEP11440.1 - 0.0012 18.2 2.2 0.61 9.4 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP11440.1 - 0.0044 17.2 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEP11440.1 - 0.014 15.4 0.1 4 7.6 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase SMP_C2CD2L PF18696.1 CEP11440.1 - 0.024 14.5 0.3 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain Ribosomal_L37e PF01907.19 CEP11441.1 - 9.5e-27 92.9 12.7 1.8e-26 92.1 12.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CEP11441.1 - 0.0062 16.5 3.1 0.011 15.8 3.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 CEP11441.1 - 0.014 15.5 1.7 0.017 15.2 1.7 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 CEP11441.1 - 0.044 13.8 1.2 0.066 13.2 1.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_5 PF14634.6 CEP11441.1 - 0.049 13.6 4.4 0.079 12.9 4.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 CEP11441.1 - 0.26 11.1 3.9 7.2 6.5 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 CEP11441.1 - 0.78 9.6 5.0 1.3 8.9 5.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.16 CEP11441.1 - 5.7 6.9 5.9 35 4.4 6.0 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit PMT PF02366.18 CEP11442.1 - 8.2e-75 251.5 12.0 1.2e-74 250.9 12.0 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CEP11442.1 - 1.9e-29 102.9 2.1 1.9e-29 102.9 2.1 3.1 3 0 0 3 3 3 1 MIR domain PMT_4TMC PF16192.5 CEP11442.1 - 1.7e-26 93.1 2.1 5.3e-26 91.5 2.1 1.9 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase NPL PF17800.1 CEP11442.1 - 9.2e-05 23.0 0.1 9.2e-05 23.0 0.1 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain Sgf11_N PF18519.1 CEP11442.1 - 0.069 12.7 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain Methyltransf_31 PF13847.6 CEP11443.1 - 1.6e-11 44.2 0.3 4.5e-11 42.8 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11443.1 - 1.3e-10 41.3 0.0 2.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP11443.1 - 4.9e-10 40.0 0.0 1.9e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11443.1 - 4e-08 33.8 0.0 1.2e-07 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP11443.1 - 5.3e-07 30.3 0.2 5.7e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 CEP11443.1 - 1.7e-06 27.8 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 CEP11443.1 - 0.0047 16.5 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CEP11443.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CEP11443.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CPSF73-100_C PF11718.8 CEP11443.1 - 0.027 14.0 1.7 0.05 13.2 1.7 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term FtsJ PF01728.19 CEP11443.1 - 0.048 13.8 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pox_MCEL PF03291.16 CEP11443.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme SelP_N PF04592.14 CEP11443.1 - 1 8.7 13.5 1.6 8.0 13.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dus PF01207.17 CEP11444.1 - 2e-50 171.7 0.0 2.4e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CEP11444.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.2 2 1 0 2 2 2 0 Histidine biosynthesis protein Ribosomal_L34 PF00468.17 CEP11445.1 - 5.3e-20 71.1 6.0 8.5e-20 70.5 6.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Methyltransf_25 PF13649.6 CEP11445.1 - 1.3e-14 54.6 0.0 3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11445.1 - 2.7e-13 50.4 0.0 5.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP11445.1 - 8e-13 48.4 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11445.1 - 6.7e-09 35.8 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP11445.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CEP11445.1 - 1.2e-05 24.9 0.0 0.00024 20.6 0.0 2.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 CEP11445.1 - 3.4e-05 24.5 0.0 6.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CEP11445.1 - 0.00016 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CEP11445.1 - 0.0044 16.8 0.0 0.026 14.3 0.0 2.0 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CEP11445.1 - 0.0048 16.5 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_8 PF05148.15 CEP11445.1 - 0.016 15.0 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.11 CEP11445.1 - 0.068 12.8 0.0 0.59 9.7 0.0 2.2 3 0 0 3 3 3 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 CEP11445.1 - 0.08 12.2 0.0 0.49 9.7 0.0 2.1 2 1 1 3 3 3 0 O-methyltransferase domain CMAS PF02353.20 CEP11445.1 - 0.089 12.1 0.0 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.17 CEP11445.1 - 0.15 11.3 0.0 0.68 9.1 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family ALP_N PF17989.1 CEP11445.1 - 0.19 11.9 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 Actin like proteins N terminal domain Usp PF00582.26 CEP11447.1 - 6e-25 88.4 0.2 9.3e-24 84.5 0.2 2.0 1 1 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 CEP11448.1 - 1.4e-69 234.4 0.0 2.3e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11448.1 - 4.9e-48 163.7 0.0 9.4e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP11448.1 - 2.9e-22 78.8 0.3 1.2e-21 76.8 0.3 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CEP11448.1 - 6.5e-07 28.5 1.5 1.3e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CEP11448.1 - 4.7e-05 22.8 0.0 8.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP11448.1 - 0.031 13.6 0.0 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 CEP11448.1 - 0.089 12.4 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 CEP11448.1 - 0.1 12.5 0.1 0.82 9.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family KCNQ2_u3 PF16642.5 CEP11448.1 - 0.81 10.7 7.9 16 6.5 0.3 3.7 3 0 0 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Med8 PF10232.9 CEP11449.1 - 2.2e-05 24.2 10.4 5.3e-05 22.9 10.4 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Kinesin PF00225.23 CEP11450.1 - 2.1e-112 375.4 0.0 3.8e-112 374.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CEP11450.1 - 1.1e-59 201.6 5.9 1.1e-59 201.6 5.9 2.2 2 0 0 2 2 2 1 Kinesin-associated DUF3694 PF12473.8 CEP11450.1 - 4.5e-29 102.1 0.1 1.5e-28 100.4 0.1 2.0 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CEP11450.1 - 2.6e-26 92.3 0.0 8.8e-26 90.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CEP11450.1 - 1.1e-06 29.1 0.2 4.5e-06 27.1 0.2 2.2 1 0 0 1 1 1 1 PH domain FHA PF00498.26 CEP11450.1 - 0.00042 20.6 0.2 0.01 16.2 0.1 3.2 3 0 0 3 3 3 1 FHA domain Rab_bind PF16704.5 CEP11450.1 - 0.72 9.9 4.5 2.3 8.3 4.5 1.9 1 0 0 1 1 1 0 Rab binding domain F-box-like PF12937.7 CEP11451.1 - 2.1e-05 24.3 0.1 8.3e-05 22.4 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP11451.1 - 0.0033 17.2 0.7 0.03 14.2 0.1 2.6 2 0 0 2 2 2 1 F-box domain LRR_2 PF07723.13 CEP11451.1 - 0.92 10.3 9.6 1.8 9.4 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 CEP11451.1 - 1.4 9.5 15.1 1.5 9.4 1.7 4.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) E1-E2_ATPase PF00122.20 CEP11452.1 - 4.1e-24 85.1 0.0 1.2e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CEP11452.1 - 5.8e-08 33.3 0.2 0.024 14.9 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP11452.1 - 0.00029 20.4 0.0 0.00029 20.4 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP11452.1 - 0.00083 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP11452.1 - 0.082 12.6 0.3 0.43 10.3 0.1 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PgaD PF13994.6 CEP11452.1 - 0.13 12.4 1.8 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 PgaD-like protein NAC PF01849.18 CEP11453.1 - 7.7e-19 67.4 0.5 3e-17 62.3 0.0 2.7 3 0 0 3 3 3 1 NAC domain Nmad3 PF18754.1 CEP11453.1 - 0.031 13.9 0.1 0.036 13.7 0.1 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Chalcone_2 PF16035.5 CEP11454.1 - 9e-38 130.1 1.2 2.2e-36 125.6 1.2 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CEP11454.1 - 9.9e-08 32.3 0.2 0.00049 20.3 0.1 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 CEP11454.1 - 0.0063 15.9 0.0 0.0099 15.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase GDPD_2 PF13653.6 CEP11454.1 - 0.025 15.0 0.2 0.07 13.6 0.2 1.8 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Isy1 PF06246.12 CEP11455.1 - 1.5e-92 309.7 7.2 1.8e-92 309.5 7.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PTPS PF01242.19 CEP11456.1 - 2.2e-33 114.8 0.4 3.1e-33 114.3 0.4 1.2 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF4899 PF16240.5 CEP11456.1 - 0.069 12.3 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Peptidase_S15 PF02129.18 CEP11457.1 - 0.00097 18.8 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CEP11457.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold ACT_7 PF13840.6 CEP11458.1 - 9.3e-23 79.8 0.0 1.4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 ACT domain HTH_23 PF13384.6 CEP11460.1 - 8.9e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP11460.1 - 0.00016 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CEP11460.1 - 0.001 19.1 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 CEP11460.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.16 CEP11460.1 - 0.0018 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_1 PF00126.27 CEP11460.1 - 0.0057 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.13 CEP11460.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_8 PF02954.19 CEP11460.1 - 0.016 15.0 0.9 0.053 13.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_17 PF12728.7 CEP11460.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 CEP11460.1 - 0.018 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 CEP11460.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_Crp_2 PF13545.6 CEP11460.1 - 0.025 14.5 0.1 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_38 PF13936.6 CEP11460.1 - 0.027 14.2 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 CEP11460.1 - 0.03 14.9 0.0 1.5 9.5 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain MarR PF01047.22 CEP11460.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 MarR family MerR_1 PF13411.6 CEP11460.1 - 0.041 14.0 0.2 0.21 11.7 0.1 2.2 2 1 0 2 2 2 0 MerR HTH family regulatory protein UPF0175 PF03683.13 CEP11460.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) MarR_2 PF12802.7 CEP11460.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 CEP11460.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF4252 PF14060.6 CEP11461.1 - 0.04 13.8 1.9 0.062 13.2 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4252) SOG2 PF10428.9 CEP11462.1 - 2.5 7.2 44.9 4 6.5 44.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein V_ATPase_I PF01496.19 CEP11463.1 - 0 1030.7 0.4 0 1030.4 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 CEP11463.1 - 0.069 13.2 0.5 0.14 12.2 0.5 1.5 1 0 0 1 1 1 0 Basic region leucine zipper GAS PF13851.6 CEP11463.1 - 0.12 11.7 1.3 0.23 10.8 1.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 CEP11463.1 - 1.2 9.2 3.8 0.79 9.9 1.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor BAR PF03114.18 CEP11464.1 - 3.2e-32 112.1 9.2 4.4e-32 111.6 9.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CEP11464.1 - 5.5e-11 42.2 0.1 1.2e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP11464.1 - 1.8e-10 40.3 0.7 3.5e-10 39.3 0.7 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP11464.1 - 4.8e-10 39.0 0.4 9.5e-10 38.0 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 CEP11464.1 - 0.00042 19.6 5.8 0.00072 18.8 5.8 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FapA PF03961.13 CEP11464.1 - 4.9 5.7 5.8 7.9 5.0 5.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 CEP11464.1 - 5.3 7.4 13.9 0.54 10.6 8.9 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NDUF_B4 PF07225.12 CEP11465.1 - 0.098 12.6 0.1 0.11 12.4 0.1 1.2 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-gamma PF00631.22 CEP11466.1 - 9.9e-23 79.9 0.0 1.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 GGL domain Orbi_VP2 PF00898.17 CEP11466.1 - 0.18 9.5 0.1 0.21 9.3 0.1 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Aconitase PF00330.20 CEP11467.1 - 1.9e-111 373.3 0.0 2.5e-110 369.6 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP11467.1 - 6.7e-21 75.0 0.0 1.5e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CEP11467.1 - 0.00025 19.9 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) COPIIcoated_ERV PF07970.12 CEP11468.1 - 1.9e-75 253.6 0.0 2.3e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEP11468.1 - 3.5e-24 85.0 0.7 1.2e-20 73.7 0.1 2.4 2 0 0 2 2 2 2 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SET PF00856.28 CEP11469.1 - 6.2e-08 33.2 1.5 1.2e-07 32.3 0.5 2.1 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEP11469.1 - 5.3e-07 29.6 7.9 5.3e-07 29.6 7.9 3.6 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CEP11469.1 - 0.011 15.8 12.5 0.18 11.9 4.6 3.6 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Miff PF05644.11 CEP11469.1 - 0.12 12.0 0.4 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Ecl1 PF12855.7 CEP11469.1 - 0.16 13.1 0.6 0.16 13.1 0.6 2.0 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Pico_P2A PF00947.19 CEP11469.1 - 6.4 6.8 6.8 0.45 10.5 0.9 2.1 2 0 0 2 2 2 0 Picornavirus core protein 2A SPRY PF00622.28 CEP11470.1 - 3.8e-21 75.4 0.1 7.4e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CEP11470.1 - 3.4e-16 59.5 0.0 5.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CEP11470.1 - 7e-05 22.6 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 LisH CENP-B_N PF04218.13 CEP11471.1 - 0.00034 20.2 0.1 0.00054 19.5 0.1 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 CEP11471.1 - 0.019 15.5 0.0 0.022 15.4 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain Trp_syntA PF00290.20 CEP11472.1 - 7.1e-95 316.7 0.8 9.1e-95 316.4 0.2 1.4 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 CEP11472.1 - 8.2e-46 156.7 0.4 1.4e-45 156.0 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 CEP11472.1 - 0.1 12.0 0.1 0.28 10.6 0.1 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein Cyclin PF08613.11 CEP11473.1 - 3.4e-34 118.5 0.4 3.4e-34 118.5 0.4 1.9 2 0 0 2 2 2 1 Cyclin Lipase_3 PF01764.25 CEP11473.1 - 1.8e-17 63.5 0.0 3.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Cyclin_N PF00134.23 CEP11473.1 - 0.05 13.3 0.1 0.097 12.4 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Methyltransf_12 PF08242.12 CEP11474.1 - 1.8e-15 57.5 0.0 5.3e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11474.1 - 4.6e-13 49.3 0.0 9.7e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP11474.1 - 1.1e-12 48.5 0.0 2.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11474.1 - 4.4e-10 40.1 0.0 9.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP11474.1 - 1e-09 38.4 0.1 1.9e-09 37.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP11474.1 - 1.3e-06 28.1 0.0 3.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CEP11474.1 - 1.5e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 CEP11474.1 - 0.00057 19.6 0.0 0.00091 18.9 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 CEP11474.1 - 0.00057 19.4 0.0 0.0055 16.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 CEP11474.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 tRNA_U5-meth_tr PF05958.11 CEP11474.1 - 0.0035 16.4 0.1 0.0035 16.4 0.1 1.5 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 CEP11474.1 - 0.0063 16.2 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 CEP11474.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TauD PF02668.16 CEP11475.1 - 1.4e-49 169.3 0.1 2e-49 168.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CEP11475.1 - 5.1e-10 39.9 0.4 1.7e-09 38.2 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 CEP11475.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.4 1 1 0 1 1 1 0 CsiD Lipase_3 PF01764.25 CEP11476.1 - 1.5e-14 54.0 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2012 PF09430.10 CEP11477.1 - 1.1e-26 93.3 0.1 1.7e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 CEP11477.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II SspB PF04386.13 CEP11477.1 - 0.054 13.4 0.2 0.093 12.6 0.2 1.3 1 0 0 1 1 1 0 Stringent starvation protein B Glyco_transf_8 PF01501.20 CEP11479.1 - 1.2e-21 77.4 0.8 1.9e-21 76.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CEP11479.1 - 0.12 11.7 0.3 0.32 10.3 0.2 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative Transferase PF02458.15 CEP11480.1 - 2e-33 115.7 0.0 2.4e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 CEP11480.1 - 0.0024 16.6 0.0 0.0042 15.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ribonuc_red_lgC PF02867.15 CEP11481.1 - 1.4e-182 607.9 0.0 1.9e-182 607.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEP11481.1 - 1.5e-23 82.6 0.0 3.8e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEP11481.1 - 5.1e-16 59.0 0.1 1.7e-15 57.4 0.1 2.0 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 CEP11481.1 - 0.083 13.1 0.2 0.26 11.6 0.2 1.8 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Y_phosphatase2 PF03162.13 CEP11481.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family FlaG PF03646.15 CEP11483.1 - 0.16 12.2 1.2 0.62 10.3 0.1 2.6 3 0 0 3 3 3 0 FlaG protein UDPGP PF01704.18 CEP11485.1 - 3e-194 645.4 1.1 3.5e-194 645.2 1.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF5633 PF18656.1 CEP11485.1 - 0.44 10.5 1.5 3.2 7.7 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) rRNA_processing PF08524.11 CEP11486.1 - 3.4e-14 53.1 35.9 4.7e-12 46.2 24.4 2.3 1 1 1 2 2 2 2 rRNA processing UvsY PF11056.8 CEP11486.1 - 0.027 14.8 2.6 0.027 14.8 2.6 1.7 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY CDC45 PF02724.14 CEP11486.1 - 1.2 7.4 21.1 1.5 7.0 21.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CEP11486.1 - 2.6 7.8 18.6 3.4 7.4 18.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABA_GPCR PF12430.8 CEP11487.1 - 1.1e-29 103.5 4.5 2e-29 102.6 4.5 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Cullin_binding PF03556.15 CEP11487.1 - 8.8e-29 100.4 6.2 8.8e-29 100.4 6.2 2.1 2 0 0 2 2 2 1 Cullin binding GPHR_N PF12537.8 CEP11487.1 - 2.8e-16 59.4 0.0 9.7e-16 57.6 0.0 2.0 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Tma16 PF11176.8 CEP11487.1 - 0.027 14.3 0.5 0.083 12.8 0.5 1.8 1 0 0 1 1 1 0 Translation machinery-associated protein 16 EF-hand_6 PF13405.6 CEP11487.1 - 0.098 12.6 0.1 13 6.1 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain HHV-1_VABD PF16852.5 CEP11490.1 - 0.049 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain TRAF6_Z2 PF18048.1 CEP11490.1 - 0.16 12.1 0.7 0.18 12.0 0.1 1.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Cnn_1N PF07989.11 CEP11492.1 - 0.061 13.5 1.1 0.13 12.4 1.1 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 RT_RNaseH_2 PF17919.1 CEP11493.1 - 2.2e-28 98.2 0.0 3.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP11493.1 - 3.3e-21 75.6 0.0 5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP11495.1 - 1.4e-13 51.0 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP11495.1 - 0.022 14.5 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 CEP11497.1 - 2.5e-08 34.4 0.0 3.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP11497.1 - 1.1e-07 32.3 0.0 1.4e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP11497.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEP11497.1 - 0.039 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Herpes_ori_bp PF02399.15 CEP11498.1 - 7.9e-08 30.9 0.1 9.6e-08 30.6 0.1 1.0 1 0 0 1 1 1 1 Origin of replication binding protein TsaE PF02367.17 CEP11498.1 - 3.4e-05 23.9 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CEP11498.1 - 6e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CEP11498.1 - 0.0036 17.3 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 CEP11498.1 - 0.0044 17.5 0.0 0.015 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEP11498.1 - 0.0056 16.4 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP11498.1 - 0.006 16.3 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP11498.1 - 0.007 16.4 0.1 0.026 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ThiF PF00899.21 CEP11498.1 - 0.0099 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family AAA_7 PF12775.7 CEP11498.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CEP11498.1 - 0.057 13.8 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CEP11498.1 - 0.083 12.8 0.1 0.41 10.5 0.1 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CEP11498.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TK PF00265.18 CEP11498.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Thymidine kinase AAA_19 PF13245.6 CEP11498.1 - 0.14 12.5 0.0 0.91 9.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Chromo PF00385.24 CEP11499.1 - 7.1e-07 29.0 0.1 1.7e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 CEP11500.1 - 8.8e-29 99.9 0.0 1.1e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP11500.1 - 2.1e-26 91.9 0.0 3.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNase_H PF00075.24 CEP11500.1 - 0.12 12.6 0.1 0.49 10.6 0.0 2.0 2 1 0 3 3 3 0 RNase H DUF5315 PF17242.2 CEP11501.1 - 0.0062 16.3 2.5 0.053 13.3 2.5 2.0 1 1 0 1 1 1 1 Disordered region of unknown function (DUF5315) Tail_VII PF17091.5 CEP11501.1 - 8.3 6.4 9.9 1.4e+03 -0.7 9.9 2.7 1 1 0 1 1 1 0 Inovirus G7P protein Retrotrans_gag PF03732.17 CEP11502.1 - 0.014 15.6 0.7 0.048 13.9 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Claudin_2 PF13903.6 CEP11502.1 - 1.2 8.8 2.8 25 4.5 0.2 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Myb_DNA-bind_6 PF13921.6 CEP11503.1 - 8.7e-06 25.9 0.8 1.7e-05 24.9 0.8 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP11503.1 - 0.00072 19.7 2.0 0.00083 19.5 0.5 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain AT_hook PF02178.19 CEP11503.1 - 0.22 11.5 5.2 0.48 10.5 5.2 1.6 1 0 0 1 1 1 0 AT hook motif Sigma_reg_N PF13800.6 CEP11504.1 - 0.069 13.4 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Tetraspanin PF00335.20 CEP11504.1 - 0.15 11.8 0.8 1.3 8.7 0.8 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF5305 PF17231.2 CEP11504.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) CtIP_N PF10482.9 CEP11504.1 - 5.5 7.1 11.9 4.6 7.3 6.6 2.6 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF5472 PF17566.2 CEP11504.1 - 6.7 6.8 5.4 40 4.3 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5472) RasGAP PF00616.19 CEP11505.1 - 4.8e-27 95.0 5.3 5.3e-18 65.5 0.0 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 CEP11505.1 - 8.1e-08 32.7 0.2 3.1e-05 24.4 0.1 3.0 2 0 0 2 2 2 1 PH domain C2 PF00168.30 CEP11505.1 - 0.00022 21.4 0.0 0.0006 20.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain CENP-B_dimeris PF09026.10 CEP11505.1 - 0.047 14.1 7.8 0.16 12.4 7.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GrpE PF01025.19 CEP11505.1 - 0.3 10.7 1.4 0.56 9.9 0.4 1.9 2 0 0 2 2 2 0 GrpE BAR_3 PF16746.5 CEP11505.1 - 0.41 10.3 8.4 0.88 9.2 0.7 3.6 4 0 0 4 4 4 0 BAR domain of APPL family SDA1 PF05285.12 CEP11505.1 - 0.9 8.9 4.2 2.1 7.7 4.2 1.5 1 0 0 1 1 1 0 SDA1 RasGEF PF00617.19 CEP11506.1 - 3.4e-41 141.4 0.7 7.2e-41 140.3 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain YL1 PF05764.13 CEP11506.1 - 0.0028 17.8 4.5 0.0028 17.8 4.5 2.8 2 1 0 2 2 2 1 YL1 nuclear protein Astro_capsid_p PF12226.8 CEP11506.1 - 0.0055 15.9 5.4 0.011 14.9 5.4 1.4 1 0 0 1 1 1 1 Turkey astrovirus capsid protein DUF4637 PF15470.6 CEP11506.1 - 1.4 8.6 8.3 0.27 10.9 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Importin_rep_4 PF18808.1 CEP11506.1 - 2.8 8.3 5.9 7.9 6.8 5.9 1.7 1 0 0 1 1 1 0 Importin repeat 4HBT_3 PF13622.6 CEP11507.1 - 5.1e-48 164.5 0.0 7.9e-48 163.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CEP11507.1 - 7e-33 113.3 0.0 4e-27 94.7 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase SMP_2 PF10144.9 CEP11507.1 - 0.087 12.5 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin TAL_FSA PF00923.19 CEP11508.1 - 1.9e-103 345.7 0.8 2.2e-103 345.6 0.8 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase TFIIIC_sub6 PF10419.9 CEP11509.1 - 1.9e-10 40.4 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Lipase_3 PF01764.25 CEP11510.1 - 8.4e-24 84.1 0.2 7.3e-22 77.8 0.2 2.5 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CEP11510.1 - 0.095 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) RhoGEF PF00621.20 CEP11512.1 - 3e-35 122.1 8.7 3e-35 122.1 8.7 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF4790 PF16037.5 CEP11512.1 - 0.071 13.6 6.0 1.7 9.2 2.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) SF3A3 PF16837.5 CEP11512.1 - 1.3 9.6 4.9 2 9.0 0.8 3.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PDZ_5 PF17817.1 CEP11513.1 - 2.5e-05 24.5 2.8 0.00012 22.3 1.0 2.1 2 0 0 2 2 2 1 PDZ domain MCM2_N PF12619.8 CEP11513.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.5 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 zf-C2H2 PF00096.26 CEP11514.1 - 4e-14 52.2 19.6 6.7e-05 23.1 0.4 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP11514.1 - 2.5e-13 49.8 20.1 3.8e-07 30.2 0.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEP11514.1 - 9.9e-09 35.0 6.6 9e-05 22.4 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP11514.1 - 1.5e-05 25.1 6.2 0.015 15.5 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP11514.1 - 0.00031 21.3 0.3 0.00031 21.3 0.3 5.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 CEP11514.1 - 0.0063 16.9 6.8 0.049 14.0 0.1 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type C5HCH PF17982.1 CEP11514.1 - 0.0086 16.2 5.0 0.064 13.4 0.2 3.0 2 0 0 2 2 2 1 NSD Cys-His rich domain zf-C2H2_aberr PF17017.5 CEP11514.1 - 0.019 15.1 2.1 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 CEP11514.1 - 0.03 14.2 0.5 0.087 12.7 0.5 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 CEP11514.1 - 1.5 8.5 5.2 9.5 5.9 0.1 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain Methyltransf_25 PF13649.6 CEP11515.1 - 6.2e-19 68.5 0.0 1.9e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP11515.1 - 1.9e-17 63.7 0.0 5e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP11515.1 - 1.1e-16 61.4 0.0 1.8e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP11515.1 - 1.8e-16 60.4 0.0 4.1e-16 59.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP11515.1 - 3.9e-16 59.2 0.0 5.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEP11515.1 - 1.5e-08 34.0 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CEP11515.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 CEP11515.1 - 3.1e-06 27.0 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 CEP11515.1 - 1.9e-05 24.4 0.0 4.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 CEP11515.1 - 2.8e-05 24.2 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP11515.1 - 7.9e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 CEP11515.1 - 0.00011 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 CEP11515.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CEP11515.1 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 CEP11515.1 - 0.00056 19.1 0.0 0.0011 18.2 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 CEP11515.1 - 0.00056 19.3 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 CEP11515.1 - 0.00076 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 CEP11515.1 - 0.0072 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 CEP11515.1 - 0.13 12.6 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase MCM PF00493.23 CEP11516.1 - 4.1e-100 333.5 0.1 5.9e-100 333.0 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEP11516.1 - 4.8e-37 126.6 0.1 9.1e-37 125.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEP11516.1 - 1.2e-29 102.5 1.0 3.1e-29 101.2 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CEP11516.1 - 1e-14 55.1 22.9 1e-14 55.1 22.9 3.3 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CEP11516.1 - 1.8e-14 54.2 0.5 1.8e-14 54.2 0.5 2.1 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEP11516.1 - 1e-08 34.8 0.1 1.3e-06 28.0 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CEP11516.1 - 3.4e-05 23.9 0.0 8.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CEP11516.1 - 0.0001 22.2 0.0 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CEP11516.1 - 0.00098 18.9 3.2 0.047 13.5 0.2 2.7 2 0 0 2 2 2 1 AAA lid domain DUF1642 PF07852.11 CEP11516.1 - 0.059 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Sigma54_activat PF00158.26 CEP11516.1 - 0.06 13.1 0.1 0.54 9.9 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Abhydrolase_3 PF07859.13 CEP11517.1 - 2.9e-52 177.6 0.0 3.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CEP11517.1 - 0.0039 16.1 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.12 CEP11517.1 - 0.0091 14.7 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CEP11517.1 - 0.01 15.3 0.0 0.074 12.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family SDH_sah PF01972.16 CEP11517.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF3020 PF11223.8 CEP11518.1 - 3.3e-20 72.3 8.0 1.3e-19 70.5 8.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) RRM_1 PF00076.22 CEP11518.1 - 4.1e-10 39.3 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Waikav_capsid_1 PF12264.8 CEP11520.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Waikavirus capsid protein 1 Fer2_4 PF13510.6 CEP11520.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Pur_ac_phosph_N PF16656.5 CEP11520.1 - 0.23 12.1 2.9 1.2 9.7 0.1 2.6 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Glyco_hydro_15 PF00723.21 CEP11521.1 - 1.7e-121 406.2 0.0 1.1e-120 403.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 CEP11521.1 - 3e-24 85.3 0.1 9e-24 83.8 0.1 1.9 1 0 0 1 1 1 1 Interleukin-like EMT inducer SHNi-TPR PF10516.9 CEP11521.1 - 0.089 12.3 1.7 0.23 10.9 0.2 2.3 2 0 0 2 2 2 0 SHNi-TPR Enolase_C PF00113.22 CEP11522.1 - 0.069 12.4 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain zf-CCHC PF00098.23 CEP11523.1 - 0.0074 16.3 10.4 0.14 12.3 0.6 2.9 3 0 0 3 3 2 2 Zinc knuckle zf-H2C2_2 PF13465.6 CEP11523.1 - 0.0074 16.7 0.9 15 6.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 CEP11523.1 - 0.041 13.3 4.8 4.1 7.0 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CEP11523.1 - 0.042 13.8 5.6 0.97 9.4 0.1 3.5 3 0 0 3 3 3 0 Nudix N-terminal DUF3268 PF11672.8 CEP11523.1 - 0.18 12.1 0.8 1 9.7 0.0 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain YhfH PF14149.6 CEP11523.1 - 0.26 11.3 3.7 41 4.2 0.0 3.5 3 0 0 3 3 3 0 YhfH-like protein BUD22 PF09073.10 CEP11523.1 - 0.52 9.6 6.2 0.77 9.0 6.2 1.3 1 0 0 1 1 1 0 BUD22 zinc_ribbon_2 PF13240.6 CEP11523.1 - 0.57 10.0 5.8 4.7 7.1 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CEP11523.1 - 1.7 8.7 6.0 2 8.4 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DNA_pol_phi PF04931.13 CEP11523.1 - 1.8 6.6 12.0 2.4 6.2 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi HypA PF01155.19 CEP11523.1 - 2.1 8.4 10.5 9.8 6.2 3.9 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CEP11523.1 - 2.2 8.4 7.1 12 6.1 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF4820 PF16091.5 CEP11523.1 - 3.3 7.0 5.3 0.41 10.0 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) zf-CCHC_2 PF13696.6 CEP11523.1 - 3.6 7.5 7.4 2.8 7.8 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle RXT2_N PF08595.11 CEP11523.1 - 3.9 7.5 8.1 0.47 10.5 3.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 CEP11523.1 - 4.5 5.4 8.1 6.1 4.9 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Prok-RING_1 PF14446.6 CEP11523.1 - 6 6.9 10.7 5.1 7.1 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 CEP11523.1 - 6.1 6.9 10.0 14 5.7 0.3 3.1 2 1 1 3 3 3 0 zinc-ribbons DUF1610 PF07754.11 CEP11523.1 - 9 6.4 7.6 47 4.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-CCHC_4 PF14392.6 CEP11523.1 - 9.5 6.0 6.9 9.9 6.0 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle PIF1 PF05970.14 CEP11524.1 - 2e-30 106.2 0.0 2.4e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP11524.1 - 0.00025 19.2 0.0 0.00029 18.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP11524.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PLDc PF00614.22 CEP11525.1 - 0.035 14.3 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Phospholipase D Active site motif SFTA2 PF15210.6 CEP11525.1 - 0.081 12.9 0.3 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Surfactant-associated protein 2 rve PF00665.26 CEP11526.1 - 3.9e-18 65.8 0.0 7.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP11526.1 - 1.4e-06 28.0 0.1 6.7e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CEP11527.1 - 1.8e-31 108.5 0.0 3.7e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP11527.1 - 3.1e-30 104.2 0.0 7.1e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP11527.1 - 2e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Phage_int_SAM_4 PF13495.6 CEP11528.1 - 0.021 15.3 0.5 0.57 10.7 0.1 2.6 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain HMG_box PF00505.19 CEP11529.1 - 4.6e-09 36.6 7.5 1e-05 25.9 1.7 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP11529.1 - 8.1e-08 32.8 17.9 1e-07 32.4 0.1 3.5 3 1 0 3 3 3 2 HMG-box domain CDC45 PF02724.14 CEP11529.1 - 0.00055 18.4 18.8 0.00081 17.8 18.8 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 CEP11529.1 - 0.033 12.4 28.5 0.049 11.9 28.5 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 CEP11529.1 - 1.1 7.8 20.0 1.7 7.1 20.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 CEP11529.1 - 1.6 8.1 22.6 0.21 11.0 18.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) LMBR1 PF04791.16 CEP11529.1 - 3.6 6.4 9.0 4.3 6.1 9.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF913 PF06025.12 CEP11529.1 - 4.6 6.1 9.6 6 5.7 9.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PLDc PF00614.22 CEP11530.1 - 5.8e-17 61.1 1.3 1.1e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEP11530.1 - 1.3e-16 60.7 1.0 3.5e-08 33.4 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PX PF00787.24 CEP11530.1 - 1.9e-10 40.7 2.1 2.1e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 PX domain PH PF00169.29 CEP11530.1 - 2.7e-06 27.8 0.5 1.7e-05 25.3 0.5 2.5 1 0 0 1 1 1 1 PH domain Pap_E4 PF02711.14 CEP11530.1 - 0.1 13.5 7.0 0.058 14.4 3.8 2.2 2 0 0 2 2 2 0 E4 protein Mito_fiss_reg PF05308.11 CEP11530.1 - 0.2 11.7 7.4 0.33 11.0 6.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 CEP11530.1 - 0.25 10.8 8.9 0.5 9.8 8.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CEP11530.1 - 3.8 7.6 12.7 11 6.1 12.7 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HMG-CoA_red PF00368.18 CEP11531.1 - 2.5e-144 480.8 2.7 3.6e-144 480.3 2.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase SWIRM-assoc_2 PF16496.5 CEP11531.1 - 0.018 13.9 0.5 0.027 13.4 0.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF3197 PF11432.8 CEP11531.1 - 0.079 12.9 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) SUIM_assoc PF16619.5 CEP11531.1 - 2.4 8.3 4.8 1.7 8.8 1.8 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Calcipressin PF04847.12 CEP11532.1 - 6.1e-31 107.6 0.4 1.2e-30 106.7 0.4 1.5 1 1 0 1 1 1 1 Calcipressin DUF3087 PF11286.8 CEP11532.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) MAS20 PF02064.15 CEP11533.1 - 4.3e-32 110.9 0.0 6.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor MRF_C1 PF13887.6 CEP11533.1 - 0.12 11.5 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 AAA_32 PF13654.6 CEP11534.1 - 0.0062 15.4 3.5 0.0063 15.4 3.5 1.0 1 0 0 1 1 1 1 AAA domain Pannexin_like PF12534.8 CEP11534.1 - 0.2 10.7 6.0 0.23 10.5 6.0 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 MAS20 PF02064.15 CEP11535.1 - 1.6e-40 138.2 1.2 1.6e-40 138.2 1.2 2.1 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 CEP11535.1 - 2.5e-08 34.5 3.5 7.1e-08 33.0 1.1 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEP11535.1 - 7.6e-05 22.7 8.7 0.00013 22.0 8.7 1.4 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 CEP11535.1 - 0.0047 16.4 4.5 0.013 14.9 4.5 1.7 1 0 0 1 1 1 1 zinc-finger of the FCS-type, C2-C2 zf-Mss51 PF13824.6 CEP11535.1 - 0.014 15.4 7.6 0.043 13.9 7.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 CEP11535.1 - 0.047 14.9 1.8 0.11 13.7 1.8 1.6 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DHH PF01368.20 CEP11535.1 - 0.073 13.3 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 DHH family Glyco_hydro_130 PF04041.13 CEP11535.1 - 0.092 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase LapA_dom PF06305.11 CEP11535.1 - 0.15 11.9 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-HIT PF04438.16 CEP11535.1 - 0.84 9.6 4.9 1.6 8.6 4.9 1.5 1 0 0 1 1 1 0 HIT zinc finger Pkinase PF00069.25 CEP11537.1 - 6e-70 235.6 0.0 1.8e-69 234.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11537.1 - 1.7e-39 135.7 0.0 3.9e-39 134.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEP11537.1 - 8.5e-05 22.0 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP11537.1 - 0.00011 22.2 0.1 0.00097 19.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP11537.1 - 0.00092 18.8 0.1 0.0064 16.1 0.1 2.2 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CEP11537.1 - 0.0021 17.4 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Ribosomal_L2_C PF03947.18 CEP11538.1 - 1.2e-45 154.8 3.5 1.2e-45 154.8 3.5 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEP11538.1 - 9.5e-16 57.5 0.1 2.6e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.12 CEP11540.1 - 5.6e-40 137.5 0.6 7.4e-40 137.1 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CEP11540.1 - 2.3e-10 40.7 0.1 0.00072 19.9 0.1 2.5 1 1 1 2 2 2 2 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.29 CEP11541.1 - 1.5e-44 151.7 0.3 4.9e-44 149.9 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP11541.1 - 6.9e-11 41.8 0.1 1.6e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEP11541.1 - 2.3e-09 37.1 0.2 2.3e-08 33.9 0.0 2.6 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CEP11541.1 - 3.9e-09 36.6 0.1 1.1e-08 35.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEP11541.1 - 6.4e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CEP11541.1 - 7.7e-08 32.9 0.2 2.1e-05 25.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CEP11541.1 - 9.2e-06 25.0 0.0 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEP11541.1 - 0.00012 22.4 1.3 0.016 15.5 1.3 2.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 CEP11541.1 - 0.00017 21.5 0.1 0.016 15.2 0.0 2.6 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CEP11541.1 - 0.00023 21.7 0.0 0.00064 20.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CEP11541.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CEP11541.1 - 0.00061 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP11541.1 - 0.0015 18.6 0.0 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEP11541.1 - 0.0021 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 CEP11541.1 - 0.0022 17.8 0.1 0.0066 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CEP11541.1 - 0.0022 17.9 0.1 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 NTPase TIP49 PF06068.13 CEP11541.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CEP11541.1 - 0.004 16.7 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CEP11541.1 - 0.0051 17.0 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CEP11541.1 - 0.0086 15.5 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CEP11541.1 - 0.0097 15.7 0.1 0.023 14.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 CEP11541.1 - 0.01 15.7 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CEP11541.1 - 0.011 15.4 0.5 0.049 13.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 CEP11541.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CEP11541.1 - 0.015 14.7 0.0 0.67 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CEP11541.1 - 0.021 14.6 0.1 0.048 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEP11541.1 - 0.028 14.2 0.1 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEP11541.1 - 0.03 13.7 1.2 0.55 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 CEP11541.1 - 0.032 14.8 0.2 0.47 11.0 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 CEP11541.1 - 0.047 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CEP11541.1 - 0.075 12.7 0.2 1.3 8.7 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CEP11541.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4972 PF16342.5 CEP11541.1 - 0.5 10.1 2.9 2.2 8.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) F-box-like PF12937.7 CEP11542.1 - 8e-12 44.9 0.5 8e-12 44.9 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP11542.1 - 4e-06 26.6 0.1 9.5e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain IQ PF00612.27 CEP11543.1 - 7.9e-06 25.2 0.2 2.1e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif CK2S PF15011.6 CEP11543.1 - 0.012 15.5 3.2 0.012 15.5 3.2 2.4 1 1 1 2 2 2 0 Casein Kinase 2 substrate CREPT PF16566.5 CEP11543.1 - 0.072 13.3 15.6 0.46 10.6 4.6 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DASH_Dad4 PF08650.10 CEP11543.1 - 0.079 12.9 1.8 0.29 11.1 1.8 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad4 betaPIX_CC PF16523.5 CEP11543.1 - 0.1 12.4 15.6 0.3 10.9 3.9 3.0 3 0 0 3 3 3 0 betaPIX coiled coil Prominin PF05478.11 CEP11543.1 - 0.33 8.9 5.3 0.63 7.9 5.3 1.4 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 CEP11543.1 - 0.43 10.8 21.5 1.7 8.8 6.9 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Lzipper-MIP1 PF14389.6 CEP11543.1 - 1 9.7 21.6 0.18 12.1 1.0 3.7 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.12 CEP11543.1 - 5.7 7.0 8.8 7.8 6.6 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 CEP11544.1 - 3.5e-22 78.8 37.0 3.5e-22 78.8 37.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CSN8_PSD8_EIF3K PF10075.9 CEP11545.1 - 3.4e-16 59.5 0.3 4.7e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CEP11545.1 - 3e-05 24.5 0.5 5e-05 23.8 0.4 1.5 1 1 0 1 1 1 1 PCI domain AIM3 PF17096.5 CEP11548.1 - 2.2 9.2 6.2 0.53 11.3 2.5 1.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 GPI-anchored PF10342.9 CEP11549.1 - 6.2e-07 30.1 0.2 6.2e-07 30.1 0.2 1.8 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAD_kinase PF01513.21 CEP11550.1 - 8.8e-71 238.5 0.0 9e-42 143.2 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DUF4551 PF15087.6 CEP11550.1 - 1.2 7.8 5.6 1.8 7.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-Mss51 PF13824.6 CEP11551.1 - 4e-19 68.5 11.8 4e-19 68.5 11.8 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 DNA_ligase_ZBD PF03119.16 CEP11551.1 - 0.042 13.9 4.4 0.2 11.7 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 CEP11551.1 - 0.044 13.8 2.9 0.09 12.8 2.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-TFIIB PF13453.6 CEP11551.1 - 0.08 12.3 4.4 0.16 11.3 4.4 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger RNA_POL_M_15KD PF02150.16 CEP11551.1 - 0.17 11.8 3.8 0.41 10.6 3.8 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-FPG_IleRS PF06827.14 CEP11551.1 - 0.37 10.7 3.0 0.75 9.7 3.0 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS OrfB_Zn_ribbon PF07282.11 CEP11551.1 - 0.67 9.9 3.5 1.5 8.8 3.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain EamA PF00892.20 CEP11553.1 - 1e-07 32.2 11.3 0.00017 21.8 2.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP11553.1 - 2.7e-07 30.1 3.8 5e-07 29.2 3.8 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 CEP11553.1 - 0.00039 19.8 2.6 0.00053 19.3 2.6 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 CEP11553.1 - 0.0022 17.3 2.4 0.0022 17.3 2.4 2.0 1 1 1 2 2 2 1 UAA transporter family SLC35F PF06027.12 CEP11553.1 - 0.22 11.0 12.3 0.043 13.3 3.5 2.0 1 1 1 2 2 2 0 Solute carrier family 35 TPT PF03151.16 CEP11553.1 - 0.3 10.4 8.7 0.023 14.0 2.6 2.0 1 1 1 2 2 2 0 Triose-phosphate Transporter family Rft-1 PF04506.13 CEP11554.1 - 5.5e-147 490.6 32.2 6.2e-147 490.4 32.2 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 CEP11554.1 - 5.5e-10 39.1 17.4 5.5e-10 39.1 17.4 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 CEP11554.1 - 5.6e-08 33.0 12.5 5.6e-08 33.0 12.5 3.7 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF4752 PF15944.5 CEP11554.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Caprin-1_C PF12287.8 CEP11555.1 - 0.06 13.5 3.3 0.081 13.1 3.3 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Cupin_8 PF13621.6 CEP11556.1 - 1.7e-31 109.9 0.0 2.6e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CEP11556.1 - 0.0006 19.4 0.3 0.0012 18.4 0.3 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Ribosomal_S9 PF00380.19 CEP11557.1 - 1.5e-43 148.1 0.3 2.7e-43 147.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SUIM_assoc PF16619.5 CEP11557.1 - 0.69 10.0 7.3 0.56 10.3 4.8 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Fcf1 PF04900.12 CEP11558.1 - 2.4e-24 85.6 0.1 7.4e-24 84.0 0.0 1.8 2 0 0 2 2 2 1 Fcf1 CBS PF00571.28 CEP11559.1 - 3.7e-31 107.4 7.9 4.1e-07 30.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 CEP11559.1 - 6.3e-11 42.1 0.2 1.9e-10 40.5 0.2 1.9 1 0 0 1 1 1 1 PB1 domain GAF PF01590.26 CEP11559.1 - 0.12 13.0 0.1 10 6.8 0.0 2.6 2 0 0 2 2 2 0 GAF domain DUF2380 PF09533.10 CEP11559.1 - 0.21 11.2 0.1 6 6.4 0.0 2.7 3 0 0 3 3 3 0 Predicted lipoprotein of unknown function (DUF2380) DUF4597 PF15366.6 CEP11559.1 - 0.57 10.0 7.5 0.1 12.3 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) BioT2 PF15368.6 CEP11559.1 - 1.8 8.5 6.3 0.37 10.7 1.0 2.5 3 0 0 3 3 3 0 Spermatogenesis family BioT2 Pox_Ag35 PF03286.14 CEP11559.1 - 6.8 6.4 12.9 0.22 11.3 4.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1764 PF08576.10 CEP11559.1 - 9.2 7.2 8.9 4.1 8.4 1.4 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) tRNA-synt_1b PF00579.25 CEP11560.1 - 6.3e-23 81.5 0.0 1.4e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) hnRNP_Q_AcD PF18360.1 CEP11560.1 - 0.16 11.9 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain EFP_N PF08207.12 CEP11561.1 - 2.6e-16 59.4 0.1 5.5e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 CEP11561.1 - 2.4e-14 52.8 0.4 4.6e-14 51.9 0.4 1.4 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 CEP11561.1 - 1.3e-08 34.7 0.1 3.2e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF3772 PF12607.8 CEP11562.1 - 0.025 14.3 0.2 0.074 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) SOBP PF15279.6 CEP11562.1 - 0.99 10.0 15.5 1.2 9.7 15.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein PhoLip_ATPase_C PF16212.5 CEP11563.1 - 3.7e-73 246.3 32.3 3.7e-73 246.3 32.3 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP11563.1 - 2.6e-23 81.5 1.8 9.1e-23 79.7 1.8 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEP11563.1 - 6.7e-15 55.0 0.0 1.5e-13 50.6 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP11563.1 - 1.6e-08 35.1 3.1 0.00023 21.5 1.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP11563.1 - 2.9e-05 23.7 11.6 7.1e-05 22.4 0.0 4.1 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP11563.1 - 5.7e-05 23.0 0.1 0.00034 20.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TGBp3 PF02495.17 CEP11563.1 - 3.7 7.3 5.6 19 5.0 0.1 3.5 3 0 0 3 3 3 0 Triple gene block 3 MPM1 PF17234.2 CEP11563.1 - 9.2 6.5 11.3 1.1 9.4 1.4 3.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Transketolase_N PF00456.21 CEP11564.1 - 5.2e-134 446.4 0.0 7.1e-134 446.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CEP11564.1 - 1.8e-42 145.0 0.0 3.3e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEP11564.1 - 7.5e-10 38.8 0.0 2.7e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CEP11564.1 - 0.0006 19.1 0.0 0.0028 16.9 0.0 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CEP11564.1 - 0.0023 16.9 0.0 0.0042 16.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 CEP11564.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DUF2280 PF10045.9 CEP11564.1 - 0.046 14.0 0.3 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Glyco_transf_28 PF03033.20 CEP11565.1 - 3.4e-22 79.0 0.0 3.2e-14 53.1 0.0 2.6 1 1 1 2 2 2 2 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CEP11565.1 - 1.3e-14 54.0 0.6 4.4e-13 49.1 0.0 3.2 3 1 0 3 3 3 1 GRAM domain UDPGT PF00201.18 CEP11565.1 - 3.1e-06 26.3 0.0 8.7e-05 21.5 0.0 2.2 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 CEP11565.1 - 0.11 13.0 0.0 0.5 10.9 0.0 2.2 1 0 0 1 1 1 0 PH domain SNARE PF05739.19 CEP11567.1 - 1e-15 57.4 3.7 1e-15 57.4 3.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CEP11567.1 - 2.1e-09 37.4 7.9 3.2e-09 36.7 7.9 1.3 1 0 0 1 1 1 1 Syntaxin DASH_Duo1 PF08651.10 CEP11567.1 - 0.0039 16.9 4.9 0.29 10.9 0.0 4.0 3 2 2 5 5 5 1 DASH complex subunit Duo1 MCPsignal PF00015.21 CEP11567.1 - 0.008 16.0 8.2 0.026 14.3 0.6 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain MRC1 PF09444.10 CEP11567.1 - 0.077 13.5 12.5 0.04 14.4 5.2 2.3 1 1 1 2 2 2 0 MRC1-like domain DUF2116 PF09889.9 CEP11567.1 - 0.2 11.6 3.5 0.44 10.6 3.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EF-G-binding_N PF07299.11 CEP11567.1 - 0.42 11.2 4.4 0.45 11.1 0.6 2.7 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal DUF1676 PF07898.13 CEP11567.1 - 0.84 9.7 4.9 2.4 8.1 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) DNA_repr_REX1B PF14966.6 CEP11567.1 - 2.8 8.7 6.8 3.2 8.5 1.6 3.1 3 1 0 3 3 2 0 DNA repair REX1-B DUF2203 PF09969.9 CEP11567.1 - 3.1 8.6 6.3 40 5.0 0.6 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Occludin_ELL PF07303.13 CEP11567.1 - 6.6 7.5 8.0 7.2 7.4 0.7 3.0 2 2 1 3 3 3 0 Occludin homology domain DUF5383 PF17355.2 CEP11567.1 - 6.7 7.1 10.9 1.2 9.5 1.3 2.9 1 1 1 3 3 3 0 Family of unknown function (DUF5383) DUF1664 PF07889.12 CEP11567.1 - 7.9 6.5 11.9 1.8 8.6 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PMT PF02366.18 CEP11568.1 - 3.8e-77 259.2 21.2 1e-76 257.8 21.2 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEP11568.1 - 7.1e-63 211.8 5.2 7.1e-63 211.8 5.2 3.5 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEP11568.1 - 6.4e-12 45.7 1.7 3.2e-11 43.4 1.7 2.1 1 1 1 2 2 2 2 MIR domain Redoxin PF08534.10 CEP11569.1 - 1.7e-30 105.7 0.0 2.5e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin MPP6 PF10175.9 CEP11569.1 - 9.3e-16 58.5 13.6 1.4e-15 57.9 13.6 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 AhpC-TSA PF00578.21 CEP11569.1 - 1.6e-08 34.5 0.1 3.3e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family AAA_11 PF13086.6 CEP11569.1 - 0.39 10.5 5.8 0.72 9.6 5.8 1.4 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.14 CEP11570.1 - 2.2e-37 128.1 0.8 1.2e-36 125.7 0.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 CEP11570.1 - 1.2e-06 28.5 0.0 6.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) ChpXY PF10216.9 CEP11570.1 - 0.056 12.6 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) Ribonuclease_3 PF00636.26 CEP11571.1 - 4.3e-41 139.8 0.1 1.5e-20 73.7 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.14 CEP11571.1 - 9e-23 80.3 0.0 1.6e-21 76.3 0.0 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 CEP11571.1 - 4.3e-20 72.1 0.2 1.1e-19 70.7 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.6 CEP11571.1 - 3e-19 69.4 0.0 1e-13 51.6 0.0 4.0 2 2 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.15 CEP11571.1 - 1.6e-12 47.8 0.1 1.6e-12 47.8 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEP11571.1 - 2.2e-10 40.6 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAZ PF02170.22 CEP11571.1 - 7.1e-07 29.1 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain gag-asp_proteas PF13975.6 CEP11571.1 - 0.18 12.4 0.0 0.56 10.8 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease COX5A PF02284.16 CEP11572.1 - 3.8e-40 136.1 0.1 4.8e-40 135.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Peptidase_M41 PF01434.18 CEP11573.1 - 1.7e-66 223.7 0.0 2.6e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CEP11573.1 - 1.3e-43 148.6 0.0 3.7e-43 147.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP11573.1 - 7.9e-14 51.2 0.1 1.8e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CEP11573.1 - 8.5e-10 39.0 0.0 2.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 CEP11573.1 - 0.0026 18.2 0.5 0.054 13.9 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CEP11573.1 - 0.0036 17.0 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEP11573.1 - 0.0044 16.3 0.1 0.0069 15.6 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CEP11573.1 - 0.0086 16.1 0.0 0.037 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEP11573.1 - 0.013 15.8 0.0 0.69 10.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEP11573.1 - 0.042 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CEP11573.1 - 0.069 13.3 0.1 0.32 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEP11573.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEP11573.1 - 0.25 10.7 0.5 0.55 9.6 0.5 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cNMP_binding PF00027.29 CEP11574.1 - 9.4e-31 105.7 0.0 1.7e-16 60.1 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 CEP11574.1 - 2.9e-17 63.5 4.9 2.5e-16 60.5 4.9 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase zf-C2H2_6 PF13912.6 CEP11575.1 - 0.004 17.1 3.8 0.0092 16.0 3.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger DUF2458 PF10454.9 CEP11575.1 - 0.028 14.1 0.5 0.053 13.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) zf-C2H2 PF00096.26 CEP11575.1 - 2.2 8.9 7.4 0.39 11.3 1.1 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type ABC_tran PF00005.27 CEP11576.1 - 4e-15 56.5 0.0 7.6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEP11576.1 - 2.7e-10 40.6 1.4 0.00031 20.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CEP11576.1 - 0.038 14.2 0.1 0.074 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain TMEM135_C_rich PF15982.5 CEP11576.1 - 0.045 14.4 0.4 0.12 12.9 0.2 1.9 2 0 0 2 2 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 RsgA_GTPase PF03193.16 CEP11576.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CEP11576.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CEP11576.1 - 0.057 13.9 0.2 0.14 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CEP11576.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CEP11576.1 - 0.078 10.5 0.5 0.11 10.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_25 PF13481.6 CEP11576.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CEP11576.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CEP11576.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family NACHT PF05729.12 CEP11576.1 - 0.14 12.0 0.1 0.41 10.6 0.1 1.8 1 0 0 1 1 1 0 NACHT domain Ribosomal_S5_C PF03719.15 CEP11577.1 - 8e-29 98.9 0.0 1.2e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CEP11577.1 - 1.4e-21 76.2 1.6 2.3e-21 75.5 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF4263 PF14082.6 CEP11577.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Fer4 PF00037.27 CEP11578.1 - 2.8e-15 55.4 15.3 5.7e-09 35.4 4.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CEP11578.1 - 1.4e-13 51.2 10.4 2.3e-13 50.5 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 CEP11578.1 - 1.1e-10 41.5 4.1 8.3e-05 22.6 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 CEP11578.1 - 1.2e-10 42.1 7.0 2.5e-05 25.1 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 CEP11578.1 - 2.2e-09 37.3 22.1 1.5e-06 28.2 12.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEP11578.1 - 5.2e-09 36.1 10.5 9e-09 35.4 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CEP11578.1 - 1.5e-07 31.7 19.0 0.00012 22.5 11.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 CEP11578.1 - 1.9e-07 30.8 11.5 0.0022 18.0 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 CEP11578.1 - 2.4e-07 30.6 17.7 0.00039 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CEP11578.1 - 1.1e-05 25.5 11.6 0.00049 20.4 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CEP11578.1 - 0.00011 22.6 12.0 0.0089 16.6 12.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 CEP11578.1 - 0.00012 22.6 9.9 0.027 15.0 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 CEP11578.1 - 0.00097 19.3 3.8 0.25 11.6 0.4 2.8 2 1 1 3 3 3 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 CEP11578.1 - 0.0063 16.6 3.7 0.15 12.2 0.2 2.3 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 CEP11578.1 - 0.0083 17.0 16.5 0.015 16.2 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_18 PF13746.6 CEP11578.1 - 0.02 15.1 9.0 2.3 8.4 9.1 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 CEP11578.1 - 0.39 11.6 11.5 2.7 8.9 1.9 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Ribonucleas_3_3 PF14622.6 CEP11579.1 - 1.9e-21 76.6 0.5 2.5e-21 76.2 0.5 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CEP11579.1 - 0.0062 17.1 0.2 0.023 15.3 0.2 1.9 1 1 0 1 1 1 1 Ribonuclease III domain SWIRM-assoc_2 PF16496.5 CEP11580.1 - 1.5e-31 109.7 7.9 3.1e-31 108.7 7.9 1.4 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 CEP11580.1 - 2e-28 98.5 0.1 2e-28 98.5 0.1 2.8 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.31 CEP11580.1 - 2.5e-11 43.6 0.1 1.4e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP11580.1 - 1.2e-05 25.4 1.7 0.0003 21.0 0.0 3.1 2 1 0 2 2 2 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CEP11580.1 - 1.3e-05 25.0 1.5 1.3e-05 25.0 1.5 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 THOC7 PF05615.13 CEP11580.1 - 0.00036 20.8 6.5 0.0012 19.1 6.5 1.9 1 0 0 1 1 1 1 Tho complex subunit 7 BRCT_2 PF16589.5 CEP11580.1 - 0.046 14.1 0.6 0.68 10.4 0.6 2.6 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Colicin_immun PF09204.10 CEP11580.1 - 0.34 11.5 3.5 0.77 10.3 0.3 2.9 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity FtsJ PF01728.19 CEP11581.1 - 1.1e-68 230.8 0.0 1.4e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase SF3b10 PF07189.11 CEP11582.1 - 4e-39 132.6 0.0 4.4e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Fungal_trans PF04082.18 CEP11583.1 - 2e-21 76.2 0.4 2e-21 76.2 0.4 2.6 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP11583.1 - 8.1e-12 45.1 12.1 1.4e-11 44.3 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4355 PF14265.6 CEP11583.1 - 0.00099 19.3 3.1 0.0026 18.0 3.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) CBS PF00571.28 CEP11584.1 - 1.7e-26 92.4 2.2 4.1e-06 27.1 0.0 4.6 4 1 0 4 4 4 4 CBS domain Peptidase_M48 PF01435.18 CEP11585.1 - 7.6e-39 133.5 0.0 1.2e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Stb3 PF10330.9 CEP11587.1 - 0.074 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein Grg1 PF11034.8 CEP11587.1 - 0.098 12.9 0.2 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 zf-C2H2_6 PF13912.6 CEP11588.1 - 0.043 13.8 0.7 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4446 PF14584.6 CEP11589.1 - 0.073 13.1 0.9 1.9 8.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DivIC PF04977.15 CEP11589.1 - 0.19 11.5 0.6 11 5.8 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 CEP11590.1 - 0.00036 20.6 2.8 0.00049 20.1 2.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CEP11590.1 - 0.068 13.7 3.5 0.092 13.3 3.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Fimbrial_PilY2 PF14481.6 CEP11590.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 ADIP PF11559.8 CEP11590.1 - 0.12 12.4 6.5 0.19 11.8 5.4 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 CEP11590.1 - 0.21 11.9 6.1 0.21 11.9 1.5 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) COMP PF11598.8 CEP11590.1 - 0.31 11.5 1.5 1.7 9.2 0.1 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein SKA2 PF16740.5 CEP11590.1 - 2.8 7.8 7.5 4.9 7.0 1.3 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 NDC10_II PF16787.5 CEP11593.1 - 9.2e-27 93.9 0.2 8.8e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP11593.1 - 1.7e-16 60.3 0.1 3.4e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SKA1 PF07160.12 CEP11593.1 - 0.09 12.6 0.6 0.16 11.8 0.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 KDZ PF18758.1 CEP11595.1 - 3.5e-22 79.1 0.1 9.5e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DDE_3 PF13358.6 CEP11596.1 - 3.3e-12 46.4 0.0 4.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Med3 PF11593.8 CEP11597.1 - 0.012 14.9 6.7 0.012 14.8 6.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.10 CEP11597.1 - 0.099 11.3 13.6 0.1 11.3 13.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.17 CEP11597.1 - 0.13 11.0 2.1 0.12 11.1 2.1 1.1 1 0 0 1 1 1 0 Presenilin DUF2722 PF10846.8 CEP11597.1 - 0.21 10.5 17.7 0.24 10.3 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CxxCxxCC PF03692.15 CEP11597.1 - 0.25 12.0 0.1 0.25 12.0 0.1 2.2 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain Hydin_ADK PF17213.3 CEP11597.1 - 0.27 11.5 4.2 0.36 11.1 4.2 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FAM150 PF15129.6 CEP11597.1 - 0.74 10.0 7.6 1.2 9.3 7.6 1.3 1 0 0 1 1 1 0 FAM150 family Spt20 PF12090.8 CEP11597.1 - 1.7 8.2 25.7 2.3 7.8 25.7 1.2 1 0 0 1 1 1 0 Spt20 family Maf1 PF09174.10 CEP11597.1 - 2.5 8.3 5.9 18 5.4 5.1 2.0 2 0 0 2 2 2 0 Maf1 regulator TFIIA PF03153.13 CEP11597.1 - 4.4 7.2 19.6 5 7.0 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.6 CEP11597.1 - 4.5 6.4 7.8 5.8 6.1 7.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TERB2 PF15101.6 CEP11597.1 - 5.7 6.9 13.4 7.5 6.6 13.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3464 PF11947.8 CEP11597.1 - 5.9 6.6 7.3 9.6 5.9 7.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pex26 PF07163.12 CEP11597.1 - 6 6.1 9.1 8.9 5.5 9.1 1.3 1 0 0 1 1 1 0 Pex26 protein EIF4E-T PF10477.9 CEP11597.1 - 7.4 5.3 13.3 8.1 5.1 13.3 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4834 PF16118.5 CEP11597.1 - 7.5 7.6 11.3 13 6.8 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RVT_1 PF00078.27 CEP11598.1 - 0.00012 21.7 0.2 0.00016 21.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP11599.1 - 2.8e-12 46.7 0.1 1.2e-11 44.5 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NCBP3 PF10309.9 CEP11600.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CEP11600.1 - 0.00041 20.3 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA binding domain PH PF00169.29 CEP11601.1 - 9.9e-11 42.1 0.1 8e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 CEP11601.1 - 0.00018 21.8 0.1 0.013 15.8 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain Vac_Fusion PF02346.16 CEP11602.1 - 0.025 14.2 6.8 0.21 11.2 0.6 3.5 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 HOOK PF05622.12 CEP11602.1 - 0.5 8.4 60.1 0.21 9.7 27.5 2.1 1 1 1 2 2 2 0 HOOK protein HJURP_C PF12347.8 CEP11602.1 - 0.85 9.7 4.0 0.45 10.6 0.4 2.3 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat EzrA PF06160.12 CEP11602.1 - 3.3 5.8 49.8 1.1 7.4 15.3 2.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Uso1_p115_C PF04871.13 CEP11602.1 - 4.9 7.6 52.0 3.2 8.1 18.0 3.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 CEP11602.1 - 6.4 6.0 42.3 4.8 6.4 21.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CEP11602.1 - 9.5 6.6 55.2 0.85 10.0 7.2 3.1 1 1 2 3 3 3 0 Fez1 HARE-HTH PF05066.13 CEP11603.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain SPT16 PF08644.11 CEP11603.1 - 0.13 12.4 4.9 1.2 9.3 0.3 3.1 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) Metallophos PF00149.28 CEP11604.1 - 2.1e-24 87.2 1.3 8.4e-24 85.2 0.3 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 CEP11604.1 - 2e-09 37.9 2.1 4.6e-09 36.7 2.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 CEP11604.1 - 7.1e-08 33.2 0.3 3.5e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C RabGAP-TBC PF00566.18 CEP11606.1 - 4.1e-41 141.0 0.1 8.6e-41 140.0 0.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CEP11606.1 - 7.3e-27 94.4 0.0 1.2e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11606.1 - 1.7e-15 57.0 0.0 3.5e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 CEP11606.1 - 0.00027 21.4 0.0 0.00064 20.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain SYF2 PF08231.12 CEP11607.1 - 2.8e-45 154.6 16.0 2.8e-45 154.6 16.0 2.4 2 1 0 2 2 2 1 SYF2 splicing factor LRR_6 PF13516.6 CEP11607.1 - 0.026 14.5 0.1 0.093 12.8 0.1 2.0 1 0 0 1 1 1 0 Leucine Rich repeat F-box-like PF12937.7 CEP11607.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like CDC37_N PF03234.14 CEP11608.1 - 2.6e-35 122.1 6.5 2.6e-35 122.1 6.5 3.0 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CEP11608.1 - 6e-32 110.0 0.6 2.1e-31 108.3 0.1 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CEP11608.1 - 8.3e-18 64.4 0.3 8.3e-18 64.4 0.3 3.2 2 1 0 2 2 2 1 Cdc37 C terminal domain NPV_P10 PF05531.12 CEP11608.1 - 0.21 12.1 7.1 2 9.0 1.2 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LMBR1 PF04791.16 CEP11608.1 - 2.8 6.7 7.5 4.2 6.2 7.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4835 PF16119.5 CEP11608.1 - 8 5.5 9.2 1.5 7.9 3.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4835) Ras PF00071.22 CEP11609.1 - 1.8e-42 144.7 0.1 3.2e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP11609.1 - 1.1e-15 57.9 0.0 2.7e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP11609.1 - 7.6e-09 35.3 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP11609.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP11609.1 - 9.6e-05 22.4 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF676 PF05057.14 CEP11609.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CEP11609.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein FeoB_N PF02421.18 CEP11609.1 - 0.0025 17.3 0.0 0.0088 15.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEP11609.1 - 0.0082 16.1 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 CEP11609.1 - 0.011 15.8 0.1 0.051 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 CEP11609.1 - 0.026 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SRPRB PF09439.10 CEP11609.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEP11609.1 - 0.061 13.7 0.0 0.28 11.5 0.0 2.1 2 1 0 3 3 3 0 AAA ATPase domain Abhydrolase_6 PF12697.7 CEP11609.1 - 0.087 13.4 0.1 0.14 12.8 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 CEP11609.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 CEP11609.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CEP11609.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GMC_oxred_N PF00732.19 CEP11610.1 - 3e-51 174.6 0.1 4.6e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CEP11610.1 - 2.7e-24 86.3 0.0 5.9e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CEP11610.1 - 2.8e-09 36.6 3.0 1.6e-05 24.2 2.9 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CEP11610.1 - 7.9e-07 28.6 0.6 4.7e-05 22.8 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP11610.1 - 5.2e-06 26.3 2.2 0.012 15.2 1.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP11610.1 - 0.0001 21.2 2.1 0.0037 16.0 1.2 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 CEP11610.1 - 0.00066 19.9 2.0 0.0016 18.6 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CEP11610.1 - 0.0019 17.5 0.4 0.003 16.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 CEP11610.1 - 0.005 16.5 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 CEP11610.1 - 0.026 13.6 0.2 0.075 12.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Cohesin_load PF10345.9 CEP11610.1 - 0.031 12.7 0.1 0.043 12.3 0.1 1.1 1 0 0 1 1 1 0 Cohesin loading factor Thi4 PF01946.17 CEP11610.1 - 0.036 13.3 0.7 0.21 10.8 0.2 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 CEP11610.1 - 0.038 13.3 5.2 0.072 12.4 5.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CEP11610.1 - 0.069 12.2 1.3 0.2 10.7 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.18 CEP11610.1 - 0.11 11.0 0.0 0.21 10.0 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 CEP11610.1 - 0.11 11.7 1.1 0.6 9.3 0.6 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP11610.1 - 0.31 11.6 3.0 1 10.0 1.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FHA PF00498.26 CEP11611.1 - 4.7e-08 33.3 0.3 2.8e-07 30.8 0.0 2.4 3 0 0 3 3 3 1 FHA domain FHA_2 PF17913.1 CEP11611.1 - 4.1e-07 30.1 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Forkhead PF00250.18 CEP11611.1 - 0.00011 22.4 1.0 0.00064 19.9 0.0 2.6 3 0 0 3 3 3 1 Forkhead domain NLRC4_HD2 PF17776.1 CEP11612.1 - 0.29 11.7 1.6 2 8.9 1.6 2.1 1 1 0 1 1 1 0 NLRC4 helical domain HD2 rve PF00665.26 CEP11613.1 - 1.1e-14 54.7 0.0 1.7e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP11613.1 - 1.3e-11 44.4 1.2 2.1e-11 43.7 1.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP11613.1 - 9e-05 22.6 1.9 0.00015 21.9 1.9 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Helitron_like_N PF14214.6 CEP11614.1 - 7.5e-41 140.4 0.0 9.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 CEP11614.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Inovirus_Gp2 PF11726.8 CEP11614.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Inovirus Gp2 Topo_Zn_Ribbon PF08272.11 CEP11614.1 - 0.17 11.6 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like HTH_23 PF13384.6 CEP11615.1 - 4.1e-05 23.2 0.3 0.00011 21.9 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP11615.1 - 0.0015 18.6 0.4 0.004 17.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain RBR PF17208.3 CEP11615.1 - 0.01 16.5 0.2 0.01 16.5 0.2 1.8 2 0 0 2 2 2 0 RNA binding Region DDE_3 PF13358.6 CEP11615.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.8 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.6 CEP11615.1 - 0.046 13.7 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix BORCS8 PF10167.9 CEP11615.1 - 0.09 12.7 0.1 0.77 9.7 0.0 2.3 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 LZ_Tnp_IS481 PF13011.6 CEP11615.1 - 0.13 12.8 0.4 0.41 11.2 0.0 2.0 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 DDE_3 PF13358.6 CEP11617.1 - 0.026 14.3 0.0 0.059 13.1 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease THDPS_M PF14789.6 CEP11617.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle RVT_1 PF00078.27 CEP11618.1 - 4.2e-06 26.4 0.1 4.7e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-set_2 PF15910.5 CEP11619.1 - 0.02 15.0 0.5 0.036 14.1 0.5 1.4 1 0 0 1 1 1 0 ICOS V-set domain YedD PF13987.6 CEP11620.1 - 0.12 12.2 0.6 0.33 10.8 0.6 1.7 1 0 0 1 1 1 0 YedD-like protein NicO PF03824.16 CEP11621.1 - 0.034 13.5 0.4 0.059 12.7 0.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 CEP11621.1 - 0.034 13.6 12.6 0.055 12.9 12.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RCC_reductase PF06405.11 CEP11621.1 - 0.078 12.2 0.2 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) PPP4R2 PF09184.11 CEP11621.1 - 1.6 8.2 13.3 2.1 7.9 13.3 1.2 1 0 0 1 1 1 0 PPP4R2 SMN PF06003.12 CEP11622.1 - 0.61 9.3 5.8 0.078 12.2 0.8 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) R3H PF01424.22 CEP11623.1 - 6.3e-17 61.3 0.1 1.1e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CEP11623.1 - 1.1e-06 28.6 35.6 0.00012 22.0 14.6 15.8 18 1 0 18 18 18 7 NF-X1 type zinc finger Clr2_transil PF16761.5 CEP11624.1 - 0.0089 16.8 1.0 0.012 16.4 0.2 1.6 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 DUF4437 PF14499.6 CEP11625.1 - 0.0096 15.1 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) MutS_V PF00488.21 CEP11626.1 - 2.6e-76 255.9 0.1 5.4e-76 254.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEP11626.1 - 2.5e-35 122.4 1.3 4.8e-35 121.5 0.2 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CEP11626.1 - 1.5e-26 92.8 4.4 7.7e-18 64.8 0.1 2.8 3 0 0 3 3 3 2 MutS domain I MutS_II PF05188.17 CEP11626.1 - 9.3e-14 51.9 0.0 2.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CEP11626.1 - 8.4e-09 35.7 0.0 2.7e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 MutS family domain IV JIP_LZII PF16471.5 CEP11626.1 - 0.059 13.5 0.0 0.28 11.4 0.0 2.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Pox_RNA_Pol_19 PF05320.12 CEP11626.1 - 0.12 12.4 7.0 0.4 10.6 7.0 2.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Lipase_3 PF01764.25 CEP11627.1 - 1.8e-18 66.8 0.0 1.2e-17 64.1 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) DDE_3 PF13358.6 CEP11627.1 - 1.4e-11 44.4 0.0 3.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP11627.1 - 0.0085 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Abhydrolase_5 PF12695.7 CEP11627.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEP11627.1 - 0.064 12.9 0.1 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CEP11627.1 - 0.066 12.8 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HTH_23 PF13384.6 CEP11627.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Abhydrolase_3 PF07859.13 CEP11627.1 - 0.094 12.6 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP11627.1 - 0.1 11.9 0.0 0.29 10.4 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_8 PF01270.17 CEP11628.1 - 7.9e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 8 Pex14_N PF04695.13 CEP11629.1 - 2.6e-15 57.4 0.8 2.6e-15 57.4 0.8 3.1 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 CEP11629.1 - 0.026 14.6 0.3 0.026 14.6 0.3 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SAT PF16073.5 CEP11629.1 - 0.032 14.0 0.4 0.056 13.2 0.4 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Exonuc_VII_L PF02601.15 CEP11629.1 - 0.17 11.4 1.5 0.26 10.8 1.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Metallophos PF00149.28 CEP11630.1 - 9.7e-33 114.4 0.2 1.8e-32 113.5 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.21 CEP11630.1 - 2.4e-23 82.9 17.4 9.1e-20 71.2 11.4 2.3 1 1 1 2 2 2 2 Cation efflux family RRM_9 PF18444.1 CEP11631.1 - 1.9e-09 37.2 0.0 4.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif PHD PF00628.29 CEP11631.1 - 1.7e-06 27.8 10.4 3.1e-06 27.0 10.4 1.4 1 0 0 1 1 1 1 PHD-finger LRR_9 PF14580.6 CEP11631.1 - 2.1e-06 27.3 0.2 4.9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CEP11631.1 - 7e-06 26.3 3.7 0.0054 17.1 0.1 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 CEP11631.1 - 0.0024 18.4 0.0 0.0081 16.7 0.0 2.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind PF09162.10 CEP11631.1 - 0.029 14.2 0.0 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 Tap, RNA-binding LRR_8 PF13855.6 CEP11631.1 - 0.29 10.9 5.7 1.5 8.7 1.9 3.4 2 1 2 4 4 4 0 Leucine rich repeat PHD_2 PF13831.6 CEP11631.1 - 0.61 9.7 5.3 1.8 8.2 5.3 1.8 1 1 0 1 1 1 0 PHD-finger DUF3808 PF10300.9 CEP11632.1 - 4.4e-62 210.4 7.9 6.4e-62 209.8 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Ribosomal_L26 PF16906.5 CEP11633.1 - 1.3e-36 124.9 4.3 1.6e-36 124.6 4.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CEP11633.1 - 2.4e-10 40.0 2.9 2.4e-10 40.0 2.9 1.8 2 0 0 2 2 2 1 KOW motif DUF1442 PF07279.11 CEP11633.1 - 0.01 15.2 1.4 0.013 14.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) tRNA_U5-meth_tr PF05958.11 CEP11635.1 - 1.4e-14 53.9 0.9 2.1e-13 50.0 0.9 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CEP11635.1 - 2e-08 34.2 0.1 5.4e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CEP11635.1 - 1.3e-07 31.3 0.3 4.6e-07 29.6 0.2 1.9 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CEP11635.1 - 9.7e-07 28.5 0.2 2e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CEP11635.1 - 2.9e-06 27.1 0.0 6.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CEP11635.1 - 4.9e-06 27.2 0.1 1.9e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CEP11635.1 - 0.00041 19.8 1.7 0.00079 18.9 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CEP11635.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CEP11635.1 - 0.0029 17.4 0.2 0.007 16.1 0.2 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 CEP11635.1 - 0.0033 16.9 0.2 0.0065 16.0 0.2 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 CEP11635.1 - 0.029 13.7 0.2 0.051 12.9 0.2 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.8 CEP11635.1 - 0.041 13.3 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DREV PF05219.12 CEP11635.1 - 0.055 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase RRM_1 PF00076.22 CEP11635.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 CEP11635.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CEP11635.1 - 0.087 12.8 1.0 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 CEP11635.1 - 0.093 12.4 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 CEP11635.1 - 0.11 13.2 0.3 0.39 11.4 0.1 2.1 2 0 0 2 2 1 0 Methyltransferase domain DXP_redisom_C PF08436.12 CEP11635.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain ATP_bind_1 PF03029.17 CEP11636.1 - 2e-86 289.7 0.2 2.5e-77 259.9 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CEP11636.1 - 0.00035 20.4 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 CEP11636.1 - 0.0052 16.8 0.0 0.0065 16.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEP11636.1 - 0.0085 16.0 0.0 4.6 7.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain SPT6_acidic PF14632.6 CEP11636.1 - 0.012 16.2 3.6 0.023 15.3 3.6 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 AAA_24 PF13479.6 CEP11636.1 - 0.043 13.5 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CEP11636.1 - 0.11 11.5 0.4 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CEP11636.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CEP11636.1 - 0.18 12.1 0.1 2.8 8.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain zf-U1 PF06220.12 CEP11636.1 - 0.3 10.9 1.2 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 U1 zinc finger FXR_C1 PF16096.5 CEP11636.1 - 5.3 7.3 6.6 1 9.6 2.9 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 PDZ_5 PF17817.1 CEP11637.1 - 0.0017 18.6 0.1 0.0052 17.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain F-box-like PF12937.7 CEP11638.1 - 2.1e-07 30.7 0.6 4.4e-07 29.7 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP11638.1 - 0.00018 21.3 0.3 0.00068 19.4 0.3 2.1 1 0 0 1 1 1 1 F-box domain LIM PF00412.22 CEP11640.1 - 1.5e-50 169.3 42.1 4.5e-14 52.4 1.8 4.3 4 0 0 4 4 4 4 LIM domain zf_UBZ PF18439.1 CEP11640.1 - 0.053 13.1 0.5 0.053 13.1 0.5 6.3 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger WRC PF08879.10 CEP11640.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.1 3 0 0 3 3 3 0 WRC NTR2 PF15458.6 CEP11640.1 - 1.7 8.2 6.9 1.2 8.7 2.0 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 DUF3725 PF12523.8 CEP11640.1 - 4.6 7.6 8.8 28 5.1 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3725) AMP-binding PF00501.28 CEP11641.1 - 1e-102 343.9 0.0 1.4e-102 343.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP11641.1 - 0.00013 22.9 0.1 0.00032 21.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YAcAr PF10686.9 CEP11641.1 - 0.18 11.8 0.1 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Pkinase PF00069.25 CEP11642.1 - 4.8e-62 209.7 0.0 1.2e-61 208.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.29 CEP11642.1 - 2.4e-51 174.0 0.0 3.4e-50 170.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.17 CEP11642.1 - 3.1e-39 134.8 0.0 6.1e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Helicase_C PF00271.31 CEP11642.1 - 3.7e-26 91.7 0.0 1.6e-25 89.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Kinase-like PF14531.6 CEP11642.1 - 5.4e-07 29.2 0.0 5.4e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 CEP11642.1 - 0.033 13.3 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CEP11642.1 - 0.16 11.9 3.6 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_16 PF10294.9 CEP11643.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase HAD_SAK_1 PF10307.9 CEP11644.1 - 2.2e-47 161.5 0.1 3.3e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Pkinase PF00069.25 CEP11645.1 - 9e-53 179.3 0.1 1e-45 156.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11645.1 - 9.3e-16 57.9 0.2 2.6e-12 46.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP11645.1 - 6e-07 29.1 0.0 1.9e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CEP11645.1 - 0.002 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP11645.1 - 0.048 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CEP11645.1 - 0.082 12.5 0.8 0.7 9.5 0.0 2.3 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEP11645.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transposase_31 PF04754.12 CEP11646.1 - 0.00019 21.1 0.4 0.00046 19.8 0.2 1.6 2 0 0 2 2 2 1 Putative transposase, YhgA-like WD40 PF00400.32 CEP11647.1 - 1.5e-09 38.3 0.3 0.00015 22.4 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11647.1 - 4.2e-08 33.4 0.0 0.0015 18.8 0.0 4.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 CEP11647.1 - 0.011 15.1 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region PDZ_5 PF17817.1 CEP11648.1 - 0.08 13.2 1.9 0.11 12.8 1.9 1.3 1 1 0 1 1 1 0 PDZ domain Pico_P2A PF00947.19 CEP11649.1 - 0.032 14.3 0.1 0.057 13.5 0.1 1.6 1 1 0 1 1 1 0 Picornavirus core protein 2A HTH_Tnp_Tc3_2 PF01498.18 CEP11650.1 - 1.6e-15 57.1 0.5 3.5e-15 56.0 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 CEP11650.1 - 0.00013 22.0 1.7 0.024 14.7 0.1 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 CEP11650.1 - 0.0025 18.4 0.1 0.0056 17.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP11650.1 - 0.0026 17.8 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 CEP11650.1 - 0.032 14.0 1.0 0.079 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain ATG11 PF10377.9 CEP11651.1 - 3.6e-22 78.8 0.1 3.6e-22 78.8 0.1 3.4 3 1 0 3 3 3 1 Autophagy-related protein 11 Turandot PF07240.11 CEP11651.1 - 0.17 11.9 3.7 0.4 10.7 0.0 3.5 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot DASH_Hsk3 PF08227.11 CEP11651.1 - 2.4 8.6 17.5 2 8.8 0.4 4.7 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like PikAIV_N PF18605.1 CEP11651.1 - 3 7.5 11.3 0.064 12.8 0.6 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Rep_fac_C PF08542.11 CEP11652.1 - 5.3e-22 78.0 0.1 1.8e-21 76.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 CEP11652.1 - 4.3e-18 66.0 0.0 9.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEP11652.1 - 3.7e-15 56.1 0.1 1.5e-11 44.4 0.1 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CEP11652.1 - 1.1e-09 38.5 0.0 2.4e-08 34.1 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CEP11652.1 - 1.1e-06 28.7 0.2 5.4e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CEP11652.1 - 1.1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CEP11652.1 - 1.7e-05 25.1 0.0 4.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 CEP11652.1 - 2.1e-05 24.4 0.0 4.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP11652.1 - 2.8e-05 24.4 0.6 0.027 14.8 0.1 2.9 1 1 2 3 3 2 2 AAA domain AAA_16 PF13191.6 CEP11652.1 - 5.8e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CEP11652.1 - 8e-05 22.4 0.0 0.00029 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP11652.1 - 0.00013 21.6 0.1 0.00044 19.8 0.0 1.9 2 1 0 2 2 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CEP11652.1 - 0.00013 21.8 0.1 0.00039 20.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CEP11652.1 - 0.00022 21.0 0.4 0.0057 16.4 0.1 2.7 3 0 0 3 3 3 1 DNA polymerase III, delta subunit DUF815 PF05673.13 CEP11652.1 - 0.00032 19.9 0.0 0.0005 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 CEP11652.1 - 0.00069 20.0 0.2 0.0043 17.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 CEP11652.1 - 0.0008 18.9 0.1 0.012 15.0 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 CEP11652.1 - 0.00084 19.1 0.2 0.01 15.7 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP11652.1 - 0.00096 19.2 0.0 0.067 13.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CEP11652.1 - 0.0033 17.3 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEP11652.1 - 0.0034 17.4 0.1 0.023 14.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CEP11652.1 - 0.0055 15.8 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 CEP11652.1 - 0.017 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CEP11652.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TPR_6 PF13174.6 CEP11652.1 - 0.024 15.2 1.4 3.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 CEP11652.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 CEP11652.1 - 0.03 14.8 0.5 0.058 13.9 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CEP11652.1 - 0.03 14.9 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CEP11652.1 - 0.038 13.4 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 CEP11652.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 CEP11652.1 - 0.04 13.3 0.1 0.42 10.0 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CEP11652.1 - 0.065 13.4 0.1 0.2 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain BrkDBD PF09607.10 CEP11652.1 - 0.1 12.4 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Brinker DNA-binding domain AAA_25 PF13481.6 CEP11652.1 - 0.12 12.0 0.6 0.45 10.0 0.2 2.1 2 1 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 CEP11652.1 - 0.16 11.8 0.2 1.6 8.6 0.1 2.3 1 1 0 2 2 2 0 NTPase GATA PF00320.27 CEP11653.1 - 1.8e-14 53.0 7.2 3.8e-14 52.0 7.2 1.5 1 0 0 1 1 1 1 GATA zinc finger DASH_Dad1 PF08649.10 CEP11653.1 - 0.31 11.3 1.0 0.63 10.3 1.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 Ras PF00071.22 CEP11654.1 - 1.2e-48 164.8 1.2 1.5e-48 164.4 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP11654.1 - 7.4e-23 81.1 0.1 1.6e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP11654.1 - 2.6e-07 30.3 0.1 3.6e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP11654.1 - 0.00038 20.0 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CEP11654.1 - 0.0034 17.2 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_32 PF13654.6 CEP11654.1 - 0.019 13.8 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain PRORP PF16953.5 CEP11654.1 - 0.059 12.9 0.2 0.069 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein-only RNase P Pro_isomerase PF00160.21 CEP11656.1 - 1.8e-41 142.1 0.3 4.6e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.23 CEP11657.1 - 3.4e-19 68.4 0.3 6.7e-19 67.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CEP11657.1 - 0.00016 22.2 0.1 0.00016 22.2 0.1 2.9 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CEP11657.1 - 0.001 18.9 1.9 0.0012 18.7 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CEP11657.1 - 0.011 15.8 0.6 0.058 13.5 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP11657.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CEP11657.1 - 0.092 13.1 0.4 0.28 11.6 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Coilin_N PF15862.5 CEP11657.1 - 4.2 7.2 11.6 20 5.0 8.2 2.4 2 0 0 2 2 2 0 Coilin N-terminus LRR_4 PF12799.7 CEP11658.1 - 0.00063 20.1 11.7 9.3 6.8 0.1 6.1 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) BUD22 PF09073.10 CEP11658.1 - 9.2 5.5 36.0 19 4.4 36.0 1.4 1 0 0 1 1 1 0 BUD22 APH PF01636.23 CEP11659.1 - 1.8e-41 142.6 0.0 2.9e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CEP11659.1 - 0.00018 20.9 0.0 0.00061 19.2 0.0 1.9 1 0 0 1 1 1 1 Ecdysteroid kinase CGI-121 PF08617.10 CEP11660.1 - 8.4e-43 146.3 0.5 9.6e-43 146.1 0.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 CDC24_OB3 PF17244.2 CEP11660.1 - 0.028 14.1 0.1 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-C2H2 PF00096.26 CEP11661.1 - 0.43 11.1 4.4 0.96 10.0 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sds3 PF08598.11 CEP11662.1 - 9.7e-19 68.2 16.7 9.7e-19 68.2 16.7 2.0 2 1 0 2 2 2 1 Sds3-like HAD PF12710.7 CEP11662.1 - 2.4e-15 57.5 2.1 5.9e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP11662.1 - 0.0026 18.1 0.0 0.05 13.9 0.0 2.7 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2783 PF10932.8 CEP11662.1 - 0.038 13.7 0.1 0.13 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) DUF4210 PF13915.6 CEP11664.1 - 6.4e-29 100.4 1.0 2e-28 98.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CEP11664.1 - 1.7e-20 72.9 0.1 4.5e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Arf PF00025.21 CEP11664.1 - 4.7e-13 49.0 0.4 1.1e-12 47.7 0.4 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family BatA PF07584.11 CEP11664.1 - 0.2 12.0 0.2 0.46 10.9 0.2 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Fer2_3 PF13085.6 CEP11665.1 - 5.7e-33 113.2 0.0 9.2e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CEP11665.1 - 2.1e-09 37.8 8.1 2.1e-09 37.8 8.1 2.3 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CEP11665.1 - 3.8e-07 30.4 8.7 3.8e-07 30.4 8.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CEP11665.1 - 2.3e-06 27.6 4.2 2.3e-06 27.6 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEP11665.1 - 0.0013 19.2 6.0 0.0013 19.2 6.0 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CEP11665.1 - 0.0014 18.5 2.3 0.012 15.6 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CEP11665.1 - 0.36 11.0 14.0 0.082 13.1 8.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 CEP11665.1 - 1.3 9.3 6.0 1.2 9.4 0.3 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Myc_N PF01056.18 CEP11667.1 - 0.00093 19.2 1.4 0.0011 18.9 1.4 1.0 1 0 0 1 1 1 1 Myc amino-terminal region NOA36 PF06524.12 CEP11668.1 - 0.47 9.7 10.0 0.43 9.9 10.0 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 CEP11668.1 - 1.7 6.6 5.8 1.4 6.9 5.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 CEP11668.1 - 6.4 4.7 10.6 5.7 4.9 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi F-box-like PF12937.7 CEP11669.1 - 9.6e-07 28.6 0.2 2.2e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP11669.1 - 0.00075 19.3 0.1 0.0015 18.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 CEP11671.1 - 0.0019 19.0 11.8 1.1 10.2 0.3 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat HEPN_SAV_6107 PF18726.1 CEP11671.1 - 0.24 11.9 1.9 1.3 9.6 0.6 2.4 2 0 0 2 2 2 0 SAV_6107-like HEPN GDP_Man_Dehyd PF16363.5 CEP11672.1 - 8.4e-60 202.9 0.8 7e-59 199.9 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP11672.1 - 1.9e-53 181.4 0.0 3e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP11672.1 - 3.4e-18 65.7 0.0 9.4e-17 60.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEP11672.1 - 2.4e-15 56.4 1.6 5.7e-15 55.2 0.0 2.3 2 1 0 2 2 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.25 CEP11672.1 - 3.7e-15 56.0 1.4 8.6e-15 54.8 0.0 2.1 2 0 0 2 2 1 1 Protein kinase domain RmlD_sub_bind PF04321.17 CEP11672.1 - 1.6e-10 40.6 0.0 1.6e-10 40.6 0.0 1.6 2 0 0 2 2 1 1 RmlD substrate binding domain adh_short PF00106.25 CEP11672.1 - 1.6e-09 37.5 0.0 3.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Pkinase_fungal PF17667.1 CEP11672.1 - 5.1e-09 35.4 8.3 8.1e-09 34.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase NAD_binding_10 PF13460.6 CEP11672.1 - 2.8e-08 33.9 0.0 5.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CEP11672.1 - 9.6e-08 32.1 0.0 2.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CEP11672.1 - 2.9e-06 26.6 0.0 2.9e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 CEP11672.1 - 0.00017 21.2 0.0 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 CEP11672.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pex14_N PF04695.13 CEP11672.1 - 0.045 14.4 14.0 0.096 13.3 14.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 CEP11672.1 - 0.17 11.8 8.0 0.3 11.0 8.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 CEP11672.1 - 0.18 11.8 2.3 0.32 11.0 2.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CEP11672.1 - 1.6 7.4 10.6 2.4 6.8 10.6 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CEP11672.1 - 2.4 7.9 9.9 4.6 7.0 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 CEP11672.1 - 2.9 8.1 7.1 6 7.1 6.5 1.8 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain AMP-binding PF00501.28 CEP11673.1 - 9.6e-97 324.2 0.1 1.2e-96 323.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP11673.1 - 5.4e-22 78.6 0.0 1.4e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEP11673.1 - 4.7e-16 58.5 4.8 6.5e-16 58.0 3.0 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Ldh_1_C PF02866.18 CEP11673.1 - 0.093 12.7 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain YjeF_N PF03853.15 CEP11674.1 - 5.7e-42 143.5 0.0 7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus bZIP_1 PF00170.21 CEP11675.1 - 1.1e-08 35.0 11.2 1.1e-08 35.0 11.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP11675.1 - 6.6e-07 29.3 11.2 2e-06 27.8 11.2 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP11675.1 - 0.00022 21.7 10.0 0.00092 19.7 10.0 2.0 1 0 0 1 1 1 1 bZIP Maf transcription factor Phage_lysis PF03245.13 CEP11675.1 - 0.0072 16.4 0.9 0.023 14.8 0.9 1.9 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein CCDC92 PF14916.6 CEP11675.1 - 0.015 15.0 0.4 0.047 13.4 0.4 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Shugoshin_N PF07558.11 CEP11675.1 - 0.022 14.6 0.3 0.063 13.1 0.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Herpes_UL6 PF01763.16 CEP11675.1 - 0.025 13.1 4.0 0.04 12.5 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CASP_C PF08172.12 CEP11675.1 - 0.026 13.9 7.1 0.079 12.3 7.1 1.9 1 0 0 1 1 1 0 CASP C terminal TSC22 PF01166.18 CEP11675.1 - 0.026 14.8 2.4 0.026 14.8 2.4 2.4 3 0 0 3 3 1 0 TSC-22/dip/bun family Vir_act_alpha_C PF10400.9 CEP11675.1 - 0.27 11.9 1.7 0.78 10.5 1.7 1.7 1 0 0 1 1 1 0 Virulence activator alpha C-term SlyX PF04102.12 CEP11675.1 - 0.3 11.7 5.7 0.19 12.4 2.0 2.7 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 CEP11675.1 - 0.41 11.1 3.8 0.42 11.0 2.1 1.9 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CEP11675.1 - 2.1 8.2 8.0 1.1 9.1 4.1 2.6 2 0 0 2 2 2 0 Septum formation initiator Uds1 PF15456.6 CEP11675.1 - 2.2 8.4 10.1 0.28 11.3 4.7 2.4 2 0 0 2 2 2 0 Up-regulated During Septation YabA PF06156.13 CEP11675.1 - 4.2 8.1 7.4 0.76 10.4 1.9 2.8 3 0 0 3 3 2 0 Initiation control protein YabA Fib_alpha PF08702.10 CEP11675.1 - 8.9 6.5 11.3 52 4.0 8.4 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_S25 PF03297.15 CEP11676.1 - 1.4e-40 137.5 2.4 1.8e-40 137.2 2.4 1.1 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.6 CEP11676.1 - 0.0085 16.1 0.4 0.0094 15.9 0.4 1.3 1 1 0 1 1 1 1 Spermatogenesis family BioT2 HTH_24 PF13412.6 CEP11676.1 - 0.016 14.8 0.5 0.024 14.2 0.5 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIPR PF10592.9 CEP11676.1 - 0.025 14.2 0.5 0.036 13.7 0.5 1.3 1 1 0 1 1 1 0 AIPR protein MarR_2 PF12802.7 CEP11676.1 - 0.029 14.3 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.12 CEP11676.1 - 0.06 12.7 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit BK_channel_a PF03493.18 CEP11677.1 - 4.7e-23 81.2 0.1 4.2e-22 78.2 0.1 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CEP11677.1 - 2.4e-14 53.0 5.8 5.9e-14 51.8 5.8 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CEP11677.1 - 0.0041 16.4 13.7 0.009 15.3 13.7 1.5 1 0 0 1 1 1 1 Ion transport protein WTF PF03303.13 CEP11677.1 - 0.032 13.9 0.3 0.088 12.5 0.3 1.7 1 0 0 1 1 1 0 WTF protein Castor_Poll_mid PF06241.12 CEP11677.1 - 0.034 14.1 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel TrkA_N PF02254.18 CEP11677.1 - 0.044 14.0 0.0 9.1 6.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain SPRY PF00622.28 CEP11678.1 - 8.4e-27 93.7 0.6 1.4e-26 92.9 0.6 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CEP11678.1 - 2.6e-23 82.5 5.0 1.1e-22 80.5 2.6 2.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CEP11678.1 - 0.00028 20.7 0.1 0.00078 19.3 0.1 1.7 1 0 0 1 1 1 1 LisH DDE_3 PF13358.6 CEP11679.1 - 1.6e-11 44.2 0.0 2.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C3HC4_2 PF13923.6 CEP11680.1 - 2.1e-10 40.3 7.2 2.1e-10 40.3 7.2 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP11680.1 - 3.1e-08 33.4 6.2 3.1e-08 33.4 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP11680.1 - 1.3e-07 31.4 8.0 1.3e-07 31.4 8.0 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP11680.1 - 5.1e-07 29.9 3.5 5.1e-07 29.9 3.5 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEP11680.1 - 6e-07 29.3 8.1 6e-07 29.3 8.1 3.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CEP11680.1 - 1.2e-06 28.7 7.5 1.2e-06 28.7 7.5 2.7 3 0 0 3 3 2 1 Ring finger domain zf-RING_6 PF14835.6 CEP11680.1 - 5.6e-05 22.9 2.3 0.00015 21.6 2.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CEP11680.1 - 0.00029 20.9 7.7 0.00029 20.9 7.7 2.3 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CEP11680.1 - 0.00096 18.9 5.9 0.00096 18.9 5.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CEP11680.1 - 0.0014 18.6 8.5 0.0014 18.6 8.5 2.2 2 0 0 2 2 1 1 RING-type zinc-finger BRCT_2 PF16589.5 CEP11680.1 - 0.0026 18.2 0.2 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Prok-RING_4 PF14447.6 CEP11680.1 - 0.0028 17.5 7.0 0.0028 17.5 7.0 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CEP11680.1 - 0.0043 17.1 3.6 0.0043 17.1 3.6 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RanBP PF00641.18 CEP11680.1 - 0.012 15.0 4.1 0.012 15.0 4.1 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 CEP11680.1 - 0.015 15.3 11.2 0.77 9.8 4.8 2.7 2 0 0 2 2 2 0 Double zinc ribbon U-box PF04564.15 CEP11680.1 - 0.072 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 U-box domain RTT107_BRCT_5 PF16770.5 CEP11680.1 - 0.076 12.9 0.4 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-ANAPC11 PF12861.7 CEP11680.1 - 0.16 12.1 5.4 0.17 12.0 1.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CEP11680.1 - 0.3 11.2 5.6 0.78 9.8 5.6 1.8 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 CEP11680.1 - 1.6 8.6 6.7 2.9 7.8 4.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit BRCT PF00533.26 CEP11680.1 - 4.4 7.8 8.4 2.1 8.8 0.3 3.9 3 2 1 4 4 3 0 BRCA1 C Terminus (BRCT) domain zinc-ribbons_6 PF07191.12 CEP11680.1 - 6.2 6.9 13.7 0.41 10.7 5.9 2.4 2 0 0 2 2 2 0 zinc-ribbons Integrase_H2C2 PF17921.1 CEP11681.1 - 2.9e-08 33.7 0.4 2.9e-08 33.7 0.4 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain PPP4R2 PF09184.11 CEP11682.1 - 9.4e-21 74.7 19.2 2.3e-20 73.4 19.2 1.5 1 1 0 1 1 1 1 PPP4R2 PTH2 PF01981.16 CEP11683.1 - 4.8e-45 152.6 0.1 1.9e-44 150.7 0.1 2.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glyco_transf_8 PF01501.20 CEP11683.1 - 1.8e-14 53.9 17.9 4.9e-14 52.5 3.1 4.2 3 1 0 3 3 3 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CEP11683.1 - 0.00094 18.6 0.0 0.004 16.5 0.0 2.1 1 0 0 1 1 1 1 Mannosyltransferase putative adh_short PF00106.25 CEP11684.1 - 7e-30 104.0 0.0 3.5e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEP11684.1 - 6.1e-16 58.7 0.0 5.3e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP11684.1 - 9.4e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP11684.1 - 7.6e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family P-mevalo_kinase PF04275.14 CEP11684.1 - 0.027 14.4 0.0 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphomevalonate kinase Exo_endo_phos PF03372.23 CEP11686.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Polysacc_deac_1 PF01522.21 CEP11688.1 - 1.8e-28 98.9 0.0 3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 CEP11688.1 - 8.2e-07 28.9 0.4 1.2e-06 28.3 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 CEP11688.1 - 1.4e-06 27.8 0.2 4e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 CEP11689.1 - 2.3e-28 98.6 0.2 5.7e-28 97.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP11689.1 - 9.2e-06 25.1 0.2 0.00024 20.4 0.1 2.5 1 1 2 3 3 3 1 Glycosyl hydrolase family 57 Dioxygenase_N PF04444.14 CEP11689.1 - 0.04 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Mnd1 PF03962.15 CEP11690.1 - 5.2e-22 77.9 0.5 5.2e-22 77.9 0.5 2.5 3 1 0 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 CEP11690.1 - 4.2e-20 71.6 1.8 1.3e-19 70.1 1.8 1.9 1 0 0 1 1 1 1 Leucine zipper with capping helix domain CaM_bdg_C0 PF10562.9 CEP11690.1 - 0.016 15.2 2.0 0.022 14.8 0.2 2.2 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit LcrG PF07216.12 CEP11690.1 - 0.037 13.9 0.6 0.067 13.1 0.6 1.6 1 0 0 1 1 1 0 LcrG protein DUF4407 PF14362.6 CEP11690.1 - 0.8 9.0 6.4 0.93 8.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lactamase_B_2 PF12706.7 CEP11692.1 - 7.4e-28 97.4 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP11692.1 - 1.7e-16 60.6 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEP11692.1 - 0.0023 18.0 0.4 1.1 9.3 0.5 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily LysM PF01476.20 CEP11693.1 - 1.5e-07 31.4 0.1 0.038 14.0 0.0 3.3 3 0 0 3 3 3 2 LysM domain Pkinase PF00069.25 CEP11695.1 - 1e-51 175.9 0.1 2e-51 174.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11695.1 - 8.1e-20 71.2 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 CEP11695.1 - 9.5e-11 41.7 0.0 0.012 15.6 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 CEP11695.1 - 1.2e-07 31.9 0.0 0.096 13.0 0.0 4.3 3 1 0 3 3 3 2 PAS domain Kinase-like PF14531.6 CEP11695.1 - 2.1e-05 24.0 0.0 5.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 CEP11695.1 - 5.1e-05 23.0 0.3 0.00011 21.9 0.3 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CEP11695.1 - 0.00014 20.9 0.9 0.00025 20.1 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CEP11695.1 - 0.00065 19.1 0.3 0.0011 18.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 CEP11695.1 - 0.0011 19.2 0.0 2.7 8.3 0.0 3.3 3 0 0 3 3 3 1 PAS fold APH PF01636.23 CEP11695.1 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP11695.1 - 0.016 14.0 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Arrestin_C PF02752.22 CEP11696.1 - 2e-19 70.4 0.4 3.1e-16 60.0 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP11696.1 - 4.2e-07 30.1 0.2 1.3e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP11696.1 - 0.0033 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like SAP30_Sin3_bdg PF13867.6 CEP11697.1 - 4e-18 65.5 0.2 8e-18 64.5 0.2 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Ish1 PF10281.9 CEP11697.1 - 0.023 15.0 0.2 0.041 14.2 0.2 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein zf-C2H2_4 PF13894.6 CEP11698.1 - 0.00025 21.6 5.4 1.1 10.2 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP11698.1 - 0.001 19.4 3.8 3.4 8.3 0.1 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP11698.1 - 0.0063 16.9 8.7 0.014 15.8 0.1 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zinc_ribbon_15 PF17032.5 CEP11698.1 - 0.0077 17.0 4.3 0.064 14.0 0.7 2.2 1 1 1 2 2 2 1 zinc-ribbon family DZR PF12773.7 CEP11698.1 - 0.02 14.9 4.7 0.14 12.2 0.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CEP11698.1 - 0.087 13.0 2.9 0.99 9.6 1.1 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Cript PF10235.9 CEP11698.1 - 0.22 12.1 5.3 1.5 9.4 1.9 2.7 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT HypA PF01155.19 CEP11698.1 - 0.43 10.6 1.9 2.8 8.0 1.9 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 CEP11698.1 - 0.45 10.9 11.7 0.5 10.7 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CEP11698.1 - 0.62 9.7 5.0 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger CwfJ_C_1 PF04677.15 CEP11700.1 - 2.5e-30 104.8 0.0 7e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 CEP11700.1 - 5.2e-30 102.9 30.1 1.8e-10 40.4 5.7 3.7 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 CEP11700.1 - 2.3e-16 60.5 0.1 6.8e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 CEP11700.1 - 1.7e-12 46.8 20.2 0.00079 19.4 1.4 3.8 3 0 0 3 3 3 3 Zinc knuckle HIT PF01230.23 CEP11700.1 - 0.0031 18.2 0.0 0.0076 17.0 0.0 1.6 1 0 0 1 1 1 1 HIT domain zinc-ribbons_6 PF07191.12 CEP11700.1 - 0.53 10.3 8.7 1.3 9.1 2.7 2.5 1 1 1 2 2 2 0 zinc-ribbons zf-CCHC_4 PF14392.6 CEP11700.1 - 0.54 10.0 13.1 3.6 7.4 0.3 3.5 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP11700.1 - 4.8 7.2 11.5 7.3 6.6 0.2 3.3 2 1 1 3 3 3 0 Zinc knuckle PHD PF00628.29 CEP11700.1 - 6.7 6.7 10.5 5.5 7.0 4.3 2.9 3 0 0 3 3 3 0 PHD-finger zf-C4_ClpX PF06689.13 CEP11700.1 - 7.7 6.5 6.5 1.3e+02 2.6 0.1 4.1 4 0 0 4 4 4 0 ClpX C4-type zinc finger E1_DerP2_DerF2 PF02221.15 CEP11702.1 - 5.2e-24 85.2 0.3 6.5e-24 84.9 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 CEP11702.1 - 5e-05 23.7 0.0 7.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.10 CEP11702.1 - 0.04 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Peptidase_M24 PF00557.24 CEP11703.1 - 1.2e-49 168.8 0.0 1.4e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4949 PF16307.5 CEP11703.1 - 0.013 15.6 0.0 0.043 14.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4949) CytochromB561_N PF09786.9 CEP11704.1 - 1.2e-05 24.6 1.8 9.2e-05 21.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome B561, N terminal Ribosomal_L10 PF00466.20 CEP11705.1 - 5.7e-24 84.2 0.3 1.2e-23 83.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CEP11705.1 - 5.6e-22 77.5 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CEP11705.1 - 3.9e-19 69.0 4.8 4.6e-19 68.8 2.9 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L27A PF00828.19 CEP11707.1 - 1.6e-20 74.1 0.8 1.6e-20 74.0 0.3 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Histone PF00125.24 CEP11708.1 - 2e-22 80.0 0.9 2.5e-22 79.6 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEP11708.1 - 7.4e-07 29.4 1.2 1.4e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CEP11708.1 - 0.00019 21.8 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CEP11708.1 - 0.022 15.0 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 CEP11708.1 - 0.092 12.4 0.3 0.79 9.3 0.3 2.0 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 CEP11709.1 - 5.3e-21 74.0 1.3 9.8e-21 73.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CEP11709.1 - 1e-16 61.5 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEP11709.1 - 2e-05 24.8 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CEP11710.1 - 9e-09 35.4 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CEP11710.1 - 3.8e-05 23.8 0.1 5.4e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CEP11710.1 - 5.4e-05 23.6 0.1 6.3e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP11710.1 - 8.9e-05 22.8 0.1 0.00012 22.4 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEP11710.1 - 0.00022 21.5 0.1 0.00042 20.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP11710.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP11710.1 - 0.08 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CEP11710.1 - 0.15 12.6 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CEP11711.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP11711.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEP11711.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEP11711.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEP11711.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP11711.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP11711.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 CEP11712.1 - 8.8e-23 81.1 1.0 1e-22 80.9 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEP11712.1 - 4.3e-07 30.1 0.7 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CEP11712.1 - 0.00017 22.0 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CEP11712.1 - 0.0079 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein RP-C PF03428.13 CEP11712.1 - 0.081 12.6 0.3 0.89 9.2 0.2 1.9 1 1 0 1 1 1 0 Replication protein C N-terminal domain RRM_1 PF00076.22 CEP11713.1 - 4.6e-08 32.8 0.1 0.0048 16.7 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 CEP11713.1 - 0.00057 19.1 5.8 0.0011 18.2 5.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Zn_ribbon_SprT PF17283.2 CEP11713.1 - 0.03 14.2 2.4 0.095 12.6 2.4 1.9 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DZR PF12773.7 CEP11713.1 - 0.099 12.7 1.7 0.2 11.7 1.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Suf PF05843.14 CEP11713.1 - 0.11 12.5 4.8 0.37 10.7 3.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TMEM164 PF14808.6 CEP11714.1 - 3.9e-20 72.3 8.3 5.4e-20 71.8 8.3 1.2 1 0 0 1 1 1 1 TMEM164 family OrfB_Zn_ribbon PF07282.11 CEP11715.1 - 0.047 13.6 1.1 0.32 11.0 1.1 2.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DRMBL PF07522.14 CEP11716.1 - 5.6e-32 110.2 0.0 1e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CEP11716.1 - 5.9e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEP11716.1 - 0.0042 17.1 0.1 0.0083 16.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RNF220 PF15926.5 CEP11716.1 - 0.0065 16.1 2.8 0.01 15.5 2.8 1.3 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Pinin_SDK_N PF04697.13 CEP11716.1 - 0.058 14.0 0.3 0.39 11.4 0.0 2.1 2 0 0 2 2 2 0 pinin/SDK conserved region Rad50_zn_hook PF04423.14 CEP11716.1 - 0.066 13.1 0.7 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Dynamin_M PF01031.20 CEP11717.1 - 4.5e-104 347.7 0.2 4.5e-104 347.7 0.2 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CEP11717.1 - 1.8e-56 190.8 0.3 1.5e-55 187.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Ribosomal_S21e PF01249.18 CEP11717.1 - 7.3e-38 128.5 0.1 1.7e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S21e GED PF02212.18 CEP11717.1 - 3.8e-26 91.1 4.6 3.8e-26 91.1 4.6 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEP11717.1 - 0.00017 21.6 0.2 0.00067 19.7 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEP11717.1 - 0.13 12.7 0.0 0.47 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S27e PF01667.17 CEP11719.1 - 6.1e-29 99.5 3.6 9.7e-29 98.9 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Acyltransferase PF01553.21 CEP11719.1 - 5.5e-16 58.4 0.0 9.9e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TF_Zn_Ribbon PF08271.12 CEP11719.1 - 0.015 14.8 3.1 0.015 14.8 3.1 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 CEP11719.1 - 0.12 12.4 1.2 0.25 11.4 1.2 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.6 CEP11719.1 - 0.39 10.7 2.2 0.73 9.8 2.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GATA PF00320.27 CEP11722.1 - 7e-20 70.3 15.3 6.1e-16 57.7 4.6 2.4 2 0 0 2 2 2 2 GATA zinc finger Elf1 PF05129.13 CEP11722.1 - 0.47 10.5 6.2 0.96 9.5 1.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.6 CEP11722.1 - 2.3 8.8 14.1 2.4 8.7 4.2 2.8 2 0 0 2 2 2 0 Cytochrome c3 Ribosomal_L32p PF01783.23 CEP11722.1 - 3 8.2 8.5 18 5.7 6.1 2.9 2 1 0 2 2 2 0 Ribosomal L32p protein family Cytochrome_C554 PF13435.6 CEP11722.1 - 7.4 7.6 11.1 1.7 9.6 1.0 3.4 2 1 1 3 3 3 0 Cytochrome c554 and c-prime p450 PF00067.22 CEP11723.1 - 5.4e-53 180.4 0.0 6.6e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ProRS-C_2 PF09181.10 CEP11723.1 - 0.024 14.8 0.0 9.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal DDE_3 PF13358.6 CEP11724.1 - 6.7e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP11724.1 - 0.038 14.6 0.0 0.082 13.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Cylicin_N PF15241.6 CEP11724.1 - 0.052 13.7 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Cylicin N-terminus CHCH PF06747.13 CEP11725.1 - 1.6e-06 28.1 6.5 2.7e-06 27.3 6.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 CEP11725.1 - 0.009 16.1 29.1 0.03 14.4 29.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CX9C PF16860.5 CEP11725.1 - 0.021 14.8 2.4 0.046 13.7 2.4 1.6 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 CEP11725.1 - 0.022 15.0 4.5 0.036 14.3 4.5 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type AflR PF08493.10 CEP11725.1 - 0.055 12.9 7.0 0.073 12.5 7.0 1.4 1 1 0 1 1 1 0 Aflatoxin regulatory protein DUF2457 PF10446.9 CEP11725.1 - 0.082 12.0 6.6 0.082 12.0 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GET2 PF08690.10 CEP11725.1 - 3.4 7.3 7.8 4.7 6.8 7.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Ndc1_Nup PF09531.10 CEP11725.1 - 6.2 5.4 8.2 6.9 5.2 8.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V-ATPase_C PF03223.15 CEP11726.1 - 7.3e-132 440.2 10.1 8.2e-132 440.1 10.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Pkinase PF00069.25 CEP11727.1 - 2.5e-69 233.6 0.0 3.9e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11727.1 - 3.4e-51 174.0 0.0 9e-51 172.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase CH PF00307.31 CEP11727.1 - 3.6e-05 23.9 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.6 CEP11727.1 - 0.002 17.5 0.0 0.0046 16.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like C1_1 PF00130.22 CEP11727.1 - 0.0086 16.0 14.4 0.0086 16.0 14.4 1.8 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 CEP11727.1 - 0.028 14.0 0.1 0.08 12.5 0.1 1.8 1 0 0 1 1 1 0 RIO1 family zf-HC5HC2H PF13771.6 CEP11727.1 - 0.29 11.4 9.2 0.97 9.7 9.2 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 CEP11727.1 - 2.9 7.9 9.2 8.3 6.4 9.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GPI-anchored PF10342.9 CEP11728.1 - 0.0053 17.5 0.0 0.0092 16.7 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DIM PF08194.12 CEP11728.1 - 0.11 12.7 0.4 0.11 12.7 0.4 2.3 2 0 0 2 2 2 0 DIM protein AA_permease PF00324.21 CEP11729.1 - 2e-126 422.4 42.5 2.5e-126 422.1 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP11729.1 - 4.4e-45 154.3 45.4 5.5e-45 154.0 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease Pterin_bind PF00809.22 CEP11730.1 - 2.4e-80 269.7 0.4 3.9e-80 269.0 0.4 1.4 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CEP11730.1 - 2.5e-47 160.0 2.3 1.4e-23 83.5 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CEP11730.1 - 7.2e-36 123.1 0.0 3e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) UQ_con PF00179.26 CEP11730.1 - 7.6e-13 48.3 0.1 2.9e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Pmp3 PF01679.17 CEP11731.1 - 1.2e-19 70.2 8.8 1.5e-19 69.9 8.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4134 PF13572.6 CEP11731.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) PrgI PF12666.7 CEP11731.1 - 0.13 13.0 0.1 0.16 12.7 0.1 1.2 1 0 0 1 1 1 0 PrgI family protein Whi5 PF08528.11 CEP11732.1 - 1e-08 34.6 0.1 1e-08 34.6 0.1 2.4 3 0 0 3 3 3 1 Whi5 like MIT PF04212.18 CEP11734.1 - 8.5e-10 38.6 0.6 2e-09 37.4 0.6 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain KilA-N PF04383.13 CEP11735.1 - 0.0029 17.4 1.8 0.0075 16.1 0.0 2.6 2 2 0 2 2 2 1 KilA-N domain Ribosomal_L29 PF00831.23 CEP11736.1 - 3.4e-13 49.3 1.9 3.4e-13 49.3 1.9 2.1 1 1 1 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 CEP11736.1 - 0.037 14.5 3.2 0.055 14.0 3.2 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Urb2 PF10441.9 CEP11736.1 - 0.076 12.9 0.4 0.1 12.5 0.4 1.2 1 0 0 1 1 1 0 Urb2/Npa2 family LTXXQ PF07813.12 CEP11736.1 - 1.2 9.9 8.4 8.1 7.2 8.5 2.3 1 1 0 1 1 1 0 LTXXQ motif family protein Meth_synt_2 PF01717.18 CEP11738.1 - 4.9e-155 515.7 0.0 2.4e-144 480.6 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CEP11738.1 - 2.2e-111 372.3 0.0 6.7e-105 351.0 0.1 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF2744 PF10910.8 CEP11738.1 - 0.082 12.9 0.4 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) RVT_1 PF00078.27 CEP11739.1 - 2e-09 37.3 0.0 3.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP11740.1 - 0.0039 16.7 0.0 0.0045 16.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YpzI PF14140.6 CEP11741.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 YpzI-like protein zf-C2H2 PF00096.26 CEP11742.1 - 5.4e-07 29.7 9.8 0.003 17.9 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CEP11742.1 - 0.00044 20.5 1.1 0.22 11.8 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP11742.1 - 0.0021 18.6 1.0 1.4 9.6 0.1 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CEP11742.1 - 0.0081 16.6 0.9 0.0081 16.6 0.9 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP11742.1 - 0.0098 16.7 7.6 1 10.4 0.7 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CEP11742.1 - 0.045 14.2 5.6 4.1 7.9 0.3 3.5 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CEP11742.1 - 0.13 12.0 1.4 0.32 10.7 1.4 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Rbx_binding PF18113.1 CEP11742.1 - 0.14 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain BCS1_N PF08740.11 CEP11742.1 - 0.44 10.5 9.9 1.5 8.7 5.9 3.0 1 1 1 2 2 2 0 BCS1 N terminal zf-C2H2_6 PF13912.6 CEP11742.1 - 0.5 10.4 5.5 0.92 9.6 0.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger DUF4587 PF15248.6 CEP11742.1 - 3.2 8.6 10.4 41 5.1 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) Mito_carr PF00153.27 CEP11743.1 - 1.2e-41 140.6 5.3 1.9e-15 56.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mur_ligase_M PF08245.12 CEP11744.1 - 1.9e-06 28.0 2.9 0.0012 18.9 0.8 3.8 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CEP11744.1 - 0.0029 17.8 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain RNA_ligase PF09414.10 CEP11744.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA ligase MoCF_biosynth PF00994.24 CEP11745.1 - 9.5e-34 116.1 0.0 1.4e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Arrestin_C PF02752.22 CEP11746.1 - 3.3e-05 24.4 0.4 0.00021 21.7 0.2 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP11746.1 - 8.7e-05 22.6 1.5 0.0023 18.0 0.0 3.1 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Retinal PF15449.6 CEP11748.1 - 6 4.5 7.5 7.6 4.2 7.5 1.0 1 0 0 1 1 1 0 Retinal protein ATP19 PF11022.8 CEP11749.1 - 0.12 12.8 0.2 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 ATP synthase subunit K T4_baseplate PF12322.8 CEP11750.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein NAGLU_N PF12971.7 CEP11750.1 - 0.2 11.5 1.0 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Mid2 PF04478.12 CEP11751.1 - 8.1e-05 22.5 0.0 8.1e-05 22.5 0.0 3.6 3 2 0 4 4 4 1 Mid2 like cell wall stress sensor Nop14 PF04147.12 CEP11751.1 - 0.02 13.1 20.1 0.026 12.7 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 CEP11751.1 - 0.45 9.6 28.4 0.72 8.9 28.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 CEP11751.1 - 0.67 9.3 22.1 0.99 8.8 22.1 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CEP11751.1 - 3.3 5.9 12.9 4.9 5.3 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CEP11751.1 - 8.5 5.6 26.7 15 4.8 26.7 1.3 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 CEP11751.1 - 9.4 3.2 18.2 12 2.9 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CX9C PF16860.5 CEP11752.1 - 5.9e-22 77.4 17.3 6.7e-14 51.6 7.6 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 CEP11752.1 - 0.0071 16.5 2.5 0.0071 16.5 2.5 2.7 1 1 2 3 3 3 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 CEP11752.1 - 0.0075 16.3 16.1 0.0094 15.9 3.6 2.5 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CEP11752.1 - 0.015 15.6 14.0 0.76 10.1 9.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 CEP11752.1 - 0.036 13.8 13.5 0.036 13.8 4.2 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RsbU_N PF08673.10 CEP11752.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain CHCH PF06747.13 CEP11752.1 - 0.26 11.5 0.3 0.26 11.5 0.3 3.3 3 0 0 3 3 3 0 CHCH domain COX17 PF05051.13 CEP11752.1 - 0.27 11.6 12.3 4.7 7.6 3.3 3.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 CEP11752.1 - 3.1 8.1 14.9 3.5 8.0 0.3 3.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) Fis1_TPR_C PF14853.6 CEP11753.1 - 3e-23 81.7 0.1 5.6e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CEP11753.1 - 1.3e-14 53.5 0.0 2.7e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 CEP11753.1 - 0.0023 18.4 0.3 0.0049 17.3 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat COPI_C PF06957.11 CEP11753.1 - 0.031 13.1 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TPR_2 PF07719.17 CEP11753.1 - 0.071 13.3 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUSP PF06337.12 CEP11755.1 - 0.0027 18.3 0.8 0.014 16.0 0.0 2.3 2 0 0 2 2 2 1 DUSP domain Mis12 PF05859.12 CEP11757.1 - 3.8e-13 49.7 1.9 3.8e-13 49.7 1.9 1.8 2 1 0 2 2 2 1 Mis12 protein FKBP_N PF01346.18 CEP11757.1 - 0.0022 18.9 3.5 0.0052 17.7 1.3 2.2 1 1 1 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AP_endonuc_2 PF01261.24 CEP11757.1 - 0.0068 15.9 0.7 0.17 11.3 0.3 2.2 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Med15_fungi PF05397.12 CEP11757.1 - 0.0075 16.5 1.9 0.0075 16.5 1.9 2.4 2 1 1 3 3 3 1 Mediator complex subunit 15 DUF4055 PF13264.6 CEP11757.1 - 0.021 14.9 0.2 0.13 12.4 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) LMBR1 PF04791.16 CEP11757.1 - 0.085 11.8 0.9 0.1 11.5 0.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 CEP11757.1 - 0.71 9.7 4.9 1.8 8.4 4.0 2.1 1 1 0 1 1 1 0 Septum formation initiator DUF16 PF01519.16 CEP11757.1 - 2.4 8.7 8.7 33 5.0 8.7 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Pkinase PF00069.25 CEP11758.1 - 3.9e-22 78.9 0.0 6.5e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 CEP11758.1 - 1.6e-15 57.2 6.5 1.4e-06 28.9 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 CEP11758.1 - 9.4e-10 37.9 5.0 0.018 15.3 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.17 CEP11758.1 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CEP11758.1 - 9.2e-07 29.2 0.1 0.0026 18.1 0.1 3.8 2 2 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CEP11758.1 - 0.0016 18.9 0.2 0.0084 16.6 0.2 2.3 1 0 0 1 1 1 1 HEAT-like repeat ANAPC4_WD40 PF12894.7 CEP11758.1 - 0.0017 18.6 0.0 3.8 7.9 0.0 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 CEP11758.1 - 0.0043 17.1 1.6 2.5 8.1 0.1 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CEP11758.1 - 0.077 13.2 1.0 6.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 APH PF01636.23 CEP11758.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CorA PF01544.18 CEP11759.1 - 2e-41 142.2 2.8 4.8e-20 72.1 0.1 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SUIM_assoc PF16619.5 CEP11759.1 - 0.016 15.2 3.7 0.04 14.0 3.7 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 CEP11759.1 - 0.095 11.5 3.1 0.15 10.9 3.1 1.2 1 0 0 1 1 1 0 Androgen receptor U3_assoc_6 PF08640.11 CEP11760.1 - 1.7e-28 98.5 5.6 1.7e-28 98.5 5.6 3.4 4 0 0 4 4 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CEP11760.1 - 7.6e-06 26.3 10.7 1.5 9.8 0.1 6.8 4 2 3 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CEP11760.1 - 1.6e-05 24.2 17.6 0.00061 19.0 1.3 4.6 4 2 1 5 5 5 3 NRDE-2, necessary for RNA interference Suf PF05843.14 CEP11760.1 - 4.5e-05 23.6 7.8 0.0013 18.8 0.2 3.6 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 CEP11760.1 - 0.0014 18.6 9.3 1.7 9.0 0.5 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11760.1 - 0.0019 18.4 8.9 6.2 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11760.1 - 0.026 14.2 6.1 1.9 8.2 0.2 5.0 5 1 1 6 6 6 0 TPR repeat ATP-synt_Z PF16594.5 CEP11760.1 - 0.21 11.1 1.0 10 5.7 0.1 2.8 3 0 0 3 3 3 0 Putative AtpZ or ATP-synthase-associated TPR_16 PF13432.6 CEP11760.1 - 0.48 11.1 7.2 10 6.8 0.0 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11760.1 - 0.92 10.1 12.8 1.2 9.7 0.3 5.7 5 2 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEP11760.1 - 3.1 7.8 17.7 13 5.7 0.3 5.8 5 2 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 CEP11760.1 - 4.7 8.1 11.1 58 4.6 0.3 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat IIGP PF05049.13 CEP11761.1 - 3.2e-24 85.7 0.0 4.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CEP11761.1 - 4.8e-07 29.8 0.0 8.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CEP11761.1 - 0.00014 22.4 0.0 0.00037 21.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 CEP11761.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 2 0 0 2 2 1 1 AAA domain Dynamin_N PF00350.23 CEP11761.1 - 0.0012 18.9 0.1 0.0038 17.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Roc PF08477.13 CEP11761.1 - 0.0024 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CEP11761.1 - 0.0032 17.4 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 CEP11761.1 - 0.0069 15.7 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 CEP11761.1 - 0.009 16.4 0.2 0.015 15.7 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP11761.1 - 0.009 16.3 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEP11761.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CEP11761.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CEP11761.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CEP11761.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CEP11761.1 - 0.038 13.1 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.18 CEP11761.1 - 0.064 12.8 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 CEP11761.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CEP11761.1 - 0.091 12.8 1.1 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 CEP11761.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CEP11761.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF498 PF04430.14 CEP11762.1 - 8.8e-29 99.8 0.0 1.6e-28 98.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Acyltransferase PF01553.21 CEP11763.1 - 4.7e-10 39.2 0.0 1.6e-08 34.3 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase EMP24_GP25L PF01105.24 CEP11763.1 - 0.0018 18.2 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Corona_nucleoca PF00937.18 CEP11763.1 - 0.033 13.2 2.1 0.058 12.4 2.1 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein GPDPase_memb PF10110.9 CEP11763.1 - 0.16 10.7 6.2 0.26 10.0 6.2 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Statherin PF03875.13 CEP11765.1 - 0.52 10.4 5.5 0.83 9.8 5.5 1.4 1 0 0 1 1 1 0 Statherin Elf4 PF07011.11 CEP11766.1 - 0.027 14.4 0.1 0.064 13.2 0.1 1.7 1 1 0 1 1 1 0 Early Flowering 4 domain Rad17 PF03215.15 CEP11766.1 - 0.056 13.4 0.3 0.12 12.3 0.2 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain NinG PF05766.12 CEP11766.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RVT_1 PF00078.27 CEP11772.1 - 1.4e-21 77.0 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CEP11773.1 - 1e-07 31.8 0.1 6.7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP11773.1 - 5e-06 27.1 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP11773.1 - 7.3e-06 26.5 0.1 1.6e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CEP11773.1 - 0.0012 18.5 0.2 0.0021 17.6 0.0 1.5 2 0 0 2 2 2 1 Ty3 transposon peptidase CRPV_capsid PF08762.10 CEP11773.1 - 0.03 14.0 0.0 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 CRPV capsid protein like RVT_1 PF00078.27 CEP11774.1 - 1.5e-24 86.8 0.1 2.8e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.20 CEP11775.1 - 3.7e-07 30.0 0.0 4.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Dam PF05869.11 CEP11776.1 - 2.7e-05 23.8 1.6 2.7e-05 23.8 1.6 2.0 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) RNase_H PF00075.24 CEP11776.1 - 0.0007 19.8 0.1 0.0011 19.2 0.1 1.3 1 1 0 1 1 1 1 RNase H Kinesin PF00225.23 CEP11779.1 - 5.5e-85 285.2 0.5 1.1e-84 284.2 0.5 3.4 3 1 1 4 4 4 2 Kinesin motor domain Kinesin_assoc PF16183.5 CEP11779.1 - 7.7e-49 166.3 3.4 7.7e-49 166.3 3.4 2.9 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 CEP11779.1 - 7.8e-42 143.5 0.3 3.1e-41 141.6 0.3 2.2 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CEP11779.1 - 1.9e-09 37.6 0.1 4.2e-07 30.0 0.0 3.2 1 1 1 2 2 2 1 Microtubule binding PH PF00169.29 CEP11779.1 - 7e-07 29.7 2.0 0.0001 22.8 0.1 2.9 1 1 1 2 2 2 2 PH domain KIF1B PF12423.8 CEP11779.1 - 0.0019 18.6 0.1 0.0078 16.6 0.1 2.2 1 0 0 1 1 1 1 Kinesin protein 1B PH_9 PF15410.6 CEP11779.1 - 0.026 14.9 0.3 0.026 14.9 0.3 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Acyltransferase PF01553.21 CEP11780.1 - 1.7e-11 43.9 0.0 4.6e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase FAD_binding_2 PF00890.24 CEP11781.1 - 1e-83 281.7 0.1 1.5e-83 281.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CEP11781.1 - 2.5e-24 85.2 0.0 3e-23 81.8 0.0 2.7 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 CEP11781.1 - 9.1e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CEP11781.1 - 3.2e-08 33.4 0.1 5.1e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEP11781.1 - 4e-08 33.4 0.3 1.8e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP11781.1 - 5.2e-05 22.6 1.1 0.00019 20.7 0.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP11781.1 - 5.3e-05 22.1 2.9 0.00051 18.9 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CEP11781.1 - 0.0025 17.1 1.3 0.031 13.5 0.0 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 CEP11781.1 - 0.0032 16.6 0.9 0.0088 15.2 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CEP11781.1 - 0.006 15.9 0.1 0.0098 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CEP11781.1 - 0.026 13.8 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEP11781.1 - 0.029 13.7 0.5 0.063 12.6 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CEP11781.1 - 0.089 11.8 0.1 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 CEP11781.1 - 0.12 11.6 0.1 0.67 9.2 0.0 2.2 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Tecti-min-caps PF09300.10 CEP11781.1 - 0.34 11.0 1.8 0.38 10.9 0.4 1.8 2 0 0 2 2 1 0 Tectiviridae, minor capsid Ribosomal_60s PF00428.19 CEP11781.1 - 2.9 8.6 6.4 2.5 8.8 3.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Galactosyl_T PF01762.21 CEP11782.1 - 3.5e-26 92.2 0.0 5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 CEP11782.1 - 9.6e-13 48.4 20.2 7.7e-12 45.5 20.2 2.1 1 1 0 1 1 1 1 N-glycosylation protein Herpes_U26 PF07402.11 CEP11782.1 - 0.0036 16.9 0.9 0.0087 15.7 0.9 1.5 1 0 0 1 1 1 1 Human herpesvirus U26 protein TM2 PF05154.16 CEP11783.1 - 6.6e-16 58.4 3.6 6.6e-16 58.4 3.6 1.7 2 0 0 2 2 2 1 TM2 domain SLC3A2_N PF16028.5 CEP11783.1 - 0.0079 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus OppC_N PF12911.7 CEP11783.1 - 0.017 15.1 0.1 0.041 13.9 0.0 1.7 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FA_hydroxylase PF04116.13 CEP11784.1 - 3e-20 72.9 15.6 3e-20 72.9 15.6 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily HECT PF00632.25 CEP11785.1 - 1.4e-75 254.7 0.0 2.9e-75 253.6 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 CEP11785.1 - 5.1e-13 49.0 0.2 1.5e-12 47.6 0.2 1.9 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DNA_ligase_A_N PF04675.14 CEP11785.1 - 0.15 12.4 3.4 0.16 12.3 1.5 1.9 2 0 0 2 2 2 0 DNA ligase N terminus CLTH PF10607.9 CEP11786.1 - 6e-24 84.6 0.4 9.8e-24 83.9 0.4 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 CEP11786.1 - 4.6e-23 81.6 0.2 1.1e-22 80.4 0.1 1.7 2 0 0 2 2 2 1 SPRY domain LisH PF08513.11 CEP11786.1 - 0.0058 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 LisH Spore_IV_A PF09547.10 CEP11786.1 - 0.0087 15.0 0.8 0.013 14.5 0.8 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Ribosomal_S10 PF00338.22 CEP11787.1 - 4.9e-33 113.3 0.0 8.2e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OPT PF03169.15 CEP11788.1 - 1.1e-148 496.6 23.2 1.3e-148 496.4 23.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cadherin_C_2 PF16492.5 CEP11788.1 - 0.67 10.7 0.1 0.67 10.7 0.1 2.2 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Ribosomal_S9 PF00380.19 CEP11789.1 - 1.2e-31 109.8 0.1 1.3e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.20 CEP11790.1 - 1.4e-104 348.4 4.4 1.6e-104 348.2 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CEP11790.1 - 0.032 14.2 0.2 0.074 13.1 0.2 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF BBS1 PF14779.6 CEP11790.1 - 0.089 12.2 0.7 0.58 9.5 0.1 2.1 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 1 TPR_19 PF14559.6 CEP11790.1 - 0.59 10.7 0.1 0.59 10.7 0.1 2.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.9 CEP11791.1 - 2.6e-49 167.7 4.6 1.3e-40 139.5 0.2 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family AMP-binding PF00501.28 CEP11792.1 - 3.3e-83 279.6 0.0 4.2e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP11792.1 - 3.6e-14 53.5 0.0 6.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vps26 PF03643.15 CEP11793.1 - 2.3e-126 420.4 6.9 2.7e-126 420.2 6.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CEP11793.1 - 0.018 15.1 1.0 0.38 10.8 0.5 3.0 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP11793.1 - 0.049 14.1 0.5 0.59 10.6 0.1 2.7 2 2 1 3 3 3 0 Arrestin (or S-antigen), C-terminal domain AAA_18 PF13238.6 CEP11794.1 - 2.4e-27 96.0 0.7 1.2e-26 93.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CEP11794.1 - 5.2e-08 33.4 0.2 1.1e-07 32.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 CEP11794.1 - 1.3e-05 25.3 0.0 0.00041 20.5 0.0 2.2 1 1 1 2 2 2 1 Adenylate kinase AAA PF00004.29 CEP11794.1 - 5.3e-05 23.7 0.8 9.8e-05 22.8 0.4 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEP11794.1 - 0.00016 21.9 0.1 0.00045 20.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEP11794.1 - 0.00017 21.8 0.1 0.00037 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CEP11794.1 - 0.0024 17.8 1.0 0.0047 16.9 1.0 1.6 1 1 0 1 1 1 1 NTPase RuvB_N PF05496.12 CEP11794.1 - 0.0031 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEP11794.1 - 0.0045 17.3 0.2 0.0071 16.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP11794.1 - 0.0059 17.0 0.2 0.012 15.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP11794.1 - 0.01 16.2 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SKI PF01202.22 CEP11794.1 - 0.021 14.9 0.2 0.039 14.1 0.2 1.4 1 1 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 CEP11794.1 - 0.023 14.4 0.1 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Mur_ligase_M PF08245.12 CEP11794.1 - 0.045 13.7 0.1 0.088 12.8 0.1 1.5 2 0 0 2 2 2 0 Mur ligase middle domain Zeta_toxin PF06414.12 CEP11794.1 - 0.049 12.9 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 CEP11794.1 - 0.051 12.6 0.2 0.078 12.0 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 CEP11794.1 - 0.057 12.9 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 dNK PF01712.19 CEP11794.1 - 0.08 12.8 1.6 0.83 9.5 0.2 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 CEP11794.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CEP11794.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 CEP11794.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ATPase PF06745.13 CEP11794.1 - 0.14 11.4 1.3 0.25 10.7 0.8 1.5 1 1 0 1 1 1 0 KaiC RNA_helicase PF00910.22 CEP11794.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 CEP11794.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.22 CEP11794.1 - 0.21 11.2 0.2 0.3 10.7 0.2 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain TPP_enzyme_N PF02776.18 CEP11795.1 - 5.9e-57 192.0 0.1 1.9e-56 190.4 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CEP11795.1 - 3.4e-52 176.3 0.6 1.9e-50 170.6 0.2 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEP11795.1 - 9e-42 142.1 0.1 2.2e-41 140.8 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 CEP11795.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg IlvN PF07991.12 CEP11796.1 - 1.5e-45 154.8 0.0 2.7e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CEP11796.1 - 7.5e-43 146.3 0.0 1e-41 142.6 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 CEP11796.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEP11796.1 - 0.026 15.1 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 CEP11796.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.20 CEP11797.1 - 3.2e-125 417.9 0.0 3.7e-125 417.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CsbD PF05532.12 CEP11798.1 - 0.00075 19.4 0.2 0.0017 18.3 0.2 1.5 1 0 0 1 1 1 1 CsbD-like ABC_membrane PF00664.23 CEP11799.1 - 6.1e-87 291.7 38.2 1.1e-45 156.4 8.3 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP11799.1 - 5.5e-52 175.9 0.0 2.9e-28 99.1 0.0 3.1 3 0 0 3 3 3 2 ABC transporter MTABC_N PF16185.5 CEP11799.1 - 2.9e-11 43.3 0.5 1.4e-10 41.1 0.5 2.2 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 CEP11799.1 - 8.4e-11 41.7 0.0 0.00012 21.5 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CEP11799.1 - 2e-06 27.9 1.9 0.0082 16.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP11799.1 - 1e-05 25.5 0.1 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CEP11799.1 - 0.00013 21.6 1.2 0.095 12.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP11799.1 - 0.0018 18.7 0.4 0.67 10.3 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CEP11799.1 - 0.0036 17.2 0.3 0.43 10.3 0.0 3.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 CEP11799.1 - 0.0084 16.2 3.4 0.018 15.1 0.3 2.4 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 CEP11799.1 - 0.023 15.2 0.2 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CEP11799.1 - 0.024 14.8 3.9 2.1 8.4 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 CEP11799.1 - 0.039 13.7 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 CEP11799.1 - 0.076 13.3 2.5 6.4 7.0 0.2 3.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 CEP11799.1 - 0.083 13.1 0.0 23 5.2 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CEP11799.1 - 0.097 12.4 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CEP11799.1 - 0.15 11.0 0.1 2.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ccdc124 PF06244.12 CEP11800.1 - 1.4e-28 100.0 22.7 1.4e-28 100.0 22.7 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Dna2 PF08696.11 CEP11800.1 - 0.31 10.8 2.6 0.6 9.9 2.6 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 Glyco_transf_49 PF13896.6 CEP11801.1 - 6.7e-60 203.2 4.3 3.3e-48 164.7 2.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF1071 PF06378.11 CEP11801.1 - 0.32 10.6 1.8 0.78 9.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1071) Sec1 PF00995.23 CEP11802.1 - 7.6e-131 438.1 4.4 8.7e-131 437.9 4.4 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 CEP11802.1 - 0.097 12.7 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain Pkinase PF00069.25 CEP11803.1 - 4.6e-71 239.3 0.0 1.5e-70 237.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11803.1 - 8.9e-47 159.5 0.0 1.7e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CEP11803.1 - 2.9e-28 98.1 0.0 5.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.23 CEP11803.1 - 4.4e-11 43.3 0.0 1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 CEP11803.1 - 2.5e-10 40.6 0.1 6.8e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CEP11803.1 - 1.6e-09 37.7 0.0 3.6e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CEP11803.1 - 1.4e-07 31.2 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP11803.1 - 0.00092 18.1 1.1 0.0018 17.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CEP11803.1 - 0.1 11.6 0.8 0.97 8.4 0.1 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 DUF2681 PF10883.8 CEP11804.1 - 0.023 15.1 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.15 CEP11804.1 - 0.18 11.6 0.3 0.39 10.5 0.1 1.6 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.32 CEP11805.1 - 3.8e-29 100.3 11.5 1.5e-07 32.0 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11805.1 - 3.1e-07 30.6 0.1 0.0036 17.6 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP11805.1 - 0.0011 18.3 0.0 0.022 14.1 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 CEP11805.1 - 0.15 10.8 0.1 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like WD40 PF00400.32 CEP11806.1 - 2.4e-10 40.8 1.5 0.00012 22.8 0.3 3.8 3 1 1 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11806.1 - 3.8e-07 30.3 0.2 0.0022 18.2 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP11806.1 - 0.064 12.6 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain VID27 PF08553.10 CEP11806.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain Kelch_1 PF01344.25 CEP11806.1 - 0.16 11.6 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Ammonium_transp PF00909.21 CEP11807.1 - 1.7e-122 409.0 25.5 1.9e-122 408.8 25.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_3_1 PF05106.12 CEP11807.1 - 0.77 10.2 7.9 0.13 12.7 1.1 2.8 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) START PF01852.19 CEP11808.1 - 1.2e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 START domain Apyrase PF06079.11 CEP11808.1 - 0.019 14.2 0.2 0.043 13.0 0.1 1.6 2 0 0 2 2 2 0 Apyrase Cadherin-like PF12733.7 CEP11808.1 - 0.1 13.1 0.8 0.25 11.9 0.8 1.6 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain WH1 PF00568.23 CEP11809.1 - 8.2e-23 80.5 0.1 1.2e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CEP11809.1 - 4e-08 33.5 0.2 1.1e-07 32.1 0.2 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 CEP11809.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 WH2 motif Ribonucleas_3_3 PF14622.6 CEP11810.1 - 4.6e-25 88.3 0.0 7.4e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CEP11810.1 - 4.5e-13 49.7 0.0 1.1e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 CEP11810.1 - 0.00016 22.3 0.0 0.00035 21.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif MIR PF02815.19 CEP11811.1 - 2.8e-14 53.4 0.1 1.1e-12 48.3 0.0 2.2 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 CEP11811.1 - 0.0038 16.5 0.0 0.0078 15.4 0.0 1.5 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor FGGY_C PF02782.16 CEP11812.1 - 1.2e-44 152.5 0.0 1.7e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CEP11812.1 - 2.8e-25 89.3 0.5 2.6e-24 86.2 0.5 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 CEP11812.1 - 0.00029 20.4 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 CEP11812.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Hexokinase MFS_1 PF07690.16 CEP11813.1 - 1.2e-30 106.6 66.2 2.3e-23 82.7 44.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP11813.1 - 4.6e-07 29.1 28.8 6.6e-06 25.3 17.1 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter F-box-like PF12937.7 CEP11814.1 - 9.7e-12 44.6 1.1 1e-10 41.3 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP11814.1 - 0.00021 21.1 0.1 0.0023 17.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 CEP11814.1 - 0.00091 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box DUF2967 PF11179.8 CEP11814.1 - 0.067 11.3 2.0 0.098 10.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) CLN3 PF02487.17 CEP11814.1 - 0.14 11.1 0.1 0.27 10.2 0.1 1.4 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 CEP11814.1 - 0.9 9.2 6.7 1.6 8.4 0.6 2.3 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 CEP11814.1 - 2.7 9.0 5.5 0.64 11.0 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Prenyltrans PF00432.21 CEP11815.1 - 2.6e-60 199.8 1.9 2.5e-16 59.1 0.0 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CEP11815.1 - 3.3e-05 23.1 0.0 2.5 7.1 0.0 3.5 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CEP11815.1 - 0.00046 19.4 0.3 0.091 11.8 0.0 2.8 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CEP11815.1 - 0.0099 14.9 0.1 0.2 10.7 0.0 2.5 3 0 0 3 3 3 1 A-macroglobulin TED domain La PF05383.17 CEP11816.1 - 6.4e-07 29.3 0.4 1.6e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 CEP11816.1 - 0.004 17.2 0.1 0.004 17.2 0.1 3.1 2 2 0 3 3 3 1 RNA binding motif TraF PF13728.6 CEP11816.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein UPF0515 PF15135.6 CEP11816.1 - 0.17 11.2 0.9 0.29 10.5 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 DUF155 PF02582.14 CEP11817.1 - 6.3e-56 189.2 2.2 8.6e-56 188.8 0.5 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Pox_Ag35 PF03286.14 CEP11817.1 - 0.12 12.1 4.8 0.048 13.5 1.6 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein LTXXQ PF07813.12 CEP11817.1 - 0.69 10.7 6.3 0.94 10.2 3.1 2.3 1 1 1 2 2 2 0 LTXXQ motif family protein SURF4 PF02077.15 CEP11818.1 - 3.1e-85 286.0 4.0 3.5e-85 285.8 4.0 1.0 1 0 0 1 1 1 1 SURF4 family Anoctamin PF04547.12 CEP11819.1 - 2.4e-112 376.0 19.2 3.1e-112 375.7 19.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Tim17 PF02466.19 CEP11820.1 - 5.4e-09 36.4 5.8 9.5e-09 35.6 5.7 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HEAT_2 PF13646.6 CEP11822.1 - 3.1e-35 120.4 4.1 5.7e-08 33.0 0.0 6.8 3 1 3 6 6 6 6 HEAT repeats HEAT PF02985.22 CEP11822.1 - 5.5e-35 116.4 24.3 0.0028 17.8 0.0 13.5 13 0 0 13 13 13 8 HEAT repeat Vac14_Fab1_bd PF12755.7 CEP11822.1 - 1e-13 51.7 4.0 0.00014 22.4 0.0 6.7 3 2 5 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CEP11822.1 - 2.7e-10 40.5 8.7 7.1e-05 23.2 0.1 6.0 6 3 2 8 8 8 4 HEAT-like repeat Cnd1 PF12717.7 CEP11822.1 - 1.2e-08 35.2 8.5 0.18 11.8 0.2 5.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CEP11822.1 - 5.5e-07 28.5 6.3 0.034 12.7 0.3 3.6 3 1 1 4 4 4 4 Adaptin N terminal region RTP1_C1 PF10363.9 CEP11822.1 - 1e-06 28.9 6.2 0.17 12.1 0.0 5.0 5 1 0 5 5 4 3 Required for nuclear transport of RNA pol II C-terminus 1 WD40 PF00400.32 CEP11822.1 - 1.1e-05 26.1 0.4 0.057 14.3 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11822.1 - 2.3e-05 24.6 0.0 0.15 12.3 0.0 4.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Arm PF00514.23 CEP11822.1 - 0.0015 18.5 3.2 27 5.0 0.0 5.4 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CEP11822.1 - 0.0039 16.8 1.0 4.3 6.8 0.0 4.0 3 1 1 4 4 4 1 CLASP N terminal DUF2415 PF10313.9 CEP11822.1 - 0.045 13.7 0.0 0.62 10.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) DNA_alkylation PF08713.11 CEP11822.1 - 0.083 12.6 0.4 2 8.1 0.0 2.9 3 0 0 3 3 3 0 DNA alkylation repair enzyme HAD_2 PF13419.6 CEP11823.1 - 1.9e-24 86.7 0.0 2.3e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP11823.1 - 2.1e-17 64.1 0.1 1.2e-15 58.4 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP11823.1 - 1.5e-06 28.2 0.2 3.5e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 CEP11823.1 - 0.00028 21.3 0.0 0.00054 20.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 CEP11823.1 - 0.075 12.8 0.0 0.3 10.8 0.0 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase DUF4187 PF13821.6 CEP11824.1 - 2.4e-22 78.5 1.5 2.4e-22 78.5 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CEP11824.1 - 1.8e-12 46.9 8.2 3.4e-12 46.0 8.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP11824.1 - 2.1e-05 24.5 1.9 2.1e-05 24.5 1.9 2.4 2 0 0 2 2 2 1 G-patch domain GATA PF00320.27 CEP11827.1 - 1.6e-26 91.6 27.7 2.1e-14 52.8 4.6 3.2 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP11827.1 - 0.00044 19.7 5.5 0.031 13.8 0.6 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding SSP160 PF06933.11 CEP11827.1 - 0.023 13.0 10.1 0.029 12.6 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Zn-ribbon_8 PF09723.10 CEP11827.1 - 0.03 14.5 2.3 1.6 8.9 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 CEP11827.1 - 0.058 13.4 4.8 0.37 10.8 1.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA eIF-5_eIF-2B PF01873.17 CEP11827.1 - 0.062 13.2 12.6 0.14 12.0 1.8 3.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CEP11827.1 - 0.068 13.3 6.9 0.11 12.6 0.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TDP43_N PF18694.1 CEP11827.1 - 0.1 12.5 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain LIM PF00412.22 CEP11827.1 - 0.54 10.5 6.0 4.4 7.6 0.6 2.8 2 0 0 2 2 2 0 LIM domain DUF3439 PF11921.8 CEP11827.1 - 2 8.4 17.2 5.3 7.0 17.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Elf1 PF05129.13 CEP11827.1 - 2.4 8.3 12.7 0.16 12.1 1.7 3.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 CEP11827.1 - 2.8 7.9 8.3 1.4 8.9 1.0 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Dicty_REP PF05086.12 CEP11827.1 - 2.9 5.7 13.1 0.082 10.9 6.1 1.8 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CEP11827.1 - 6.1 6.8 25.2 14 5.6 25.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein HTH_15 PF12324.8 CEP11828.1 - 0.13 12.2 0.9 18 5.4 0.1 3.1 2 1 1 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase BAP PF06639.11 CEP11828.1 - 0.13 12.6 4.0 0.34 11.3 0.4 2.4 2 1 0 2 2 2 0 Basal layer antifungal peptide (BAP) bZIP_Maf PF03131.17 CEP11829.1 - 0.0047 17.4 2.5 0.0047 17.4 2.5 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor Ribonuclease_3 PF00636.26 CEP11830.1 - 1.2e-45 154.4 0.0 5.3e-23 81.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CEP11830.1 - 7.8e-29 100.4 0.0 3.5e-17 62.8 0.0 3.0 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 CEP11830.1 - 1.1e-21 76.8 4.4 1.3e-20 73.4 0.1 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.31 CEP11830.1 - 1.3e-19 70.6 0.4 3.5e-19 69.2 0.4 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP11830.1 - 3.9e-11 43.0 0.0 7.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PAZ PF02170.22 CEP11830.1 - 8.9e-11 41.8 0.4 1.8e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 PAZ domain ResIII PF04851.15 CEP11830.1 - 1e-08 35.4 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 CEP11830.1 - 0.00035 21.2 3.5 0.00045 20.9 0.6 2.7 3 0 0 3 3 3 1 Double-stranded RNA binding motif AAA_22 PF13401.6 CEP11830.1 - 0.14 12.5 0.0 0.48 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain GATase_5 PF13507.6 CEP11831.1 - 7.3e-103 343.2 0.0 1e-102 342.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CEP11831.1 - 1.9e-42 145.1 0.6 6.2e-29 101.1 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CEP11831.1 - 1.4e-31 108.8 0.0 2.5e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CEP11831.1 - 2.8e-22 79.0 0.0 2.9e-21 75.8 0.0 2.6 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain TRP_2 PF08344.11 CEP11831.1 - 0.079 13.2 0.3 1.3 9.3 0.1 2.7 3 0 0 3 3 3 0 Transient receptor ion channel II Glyco_hydro_31 PF01055.26 CEP11833.1 - 1.2e-104 351.0 3.7 1.6e-104 350.5 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEP11833.1 - 1.7e-18 66.7 0.9 4.8e-18 65.2 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 CEP11833.1 - 0.00036 20.8 0.1 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 CEP11833.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Polysacc_deac_3 PF15421.6 CEP11833.1 - 0.025 13.1 0.2 1.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative polysaccharide deacetylase DNA_pol_A_exo1 PF01612.20 CEP11834.1 - 1.5e-48 164.8 0.3 2.5e-48 164.1 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CEP11834.1 - 1.1e-21 77.3 0.0 2.9e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CEP11834.1 - 5.6e-12 45.5 0.0 2.1e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 HRDC domain Glyco_hydro_47 PF01532.20 CEP11835.1 - 8e-145 483.2 0.0 9.6e-145 483.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Tetraspanin PF00335.20 CEP11838.1 - 6.4e-15 55.5 10.7 8.6e-15 55.1 10.7 1.2 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.23 CEP11838.1 - 1.1 9.3 8.5 3.1 7.8 8.5 1.8 1 1 0 1 1 1 0 Membrane-associating domain Mog1 PF04603.12 CEP11839.1 - 8e-37 126.7 0.9 1.2e-36 126.2 0.9 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF1864 PF08933.11 CEP11839.1 - 0.024 13.4 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Stealth_CR2 PF11380.8 CEP11839.1 - 0.045 13.9 0.2 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 HisKA_2 PF07568.12 CEP11841.1 - 0.026 14.6 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase Septin PF00735.18 CEP11842.1 - 2.8e-55 187.6 4.0 5.3e-41 140.7 2.1 2.0 2 0 0 2 2 2 2 Septin Cyclin PF08613.11 CEP11843.1 - 1.3e-42 145.9 0.1 2.9e-42 144.8 0.1 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP11843.1 - 0.046 13.5 1.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain Peptidase_M17 PF00883.21 CEP11844.1 - 4.9e-119 397.2 0.2 7.7e-119 396.6 0.2 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CEP11844.1 - 6.9e-13 48.6 2.1 1.3e-12 47.6 2.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Sterol-sensing PF12349.8 CEP11845.1 - 1.4e-28 99.7 4.8 4.2e-28 98.1 4.8 1.9 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEP11845.1 - 1.6e-12 46.4 4.7 2.6e-12 45.7 4.7 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CEP11845.1 - 2e-12 47.4 12.8 0.058 14.3 0.4 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 CEP11845.1 - 1.6e-06 27.1 6.6 0.098 11.3 1.1 3.9 3 1 1 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEP11845.1 - 0.00022 21.5 0.9 3.3 8.1 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 CEP11845.1 - 1.1 9.4 9.5 1.2 9.2 4.8 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 p450 PF00067.22 CEP11847.1 - 6.8e-74 249.3 0.0 8.7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5087 PF17006.5 CEP11847.1 - 0.016 14.8 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) Arrestin_C PF02752.22 CEP11848.1 - 7.9e-18 65.2 0.6 7.9e-14 52.2 0.3 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP11848.1 - 7.1e-15 55.3 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP11848.1 - 0.00056 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like CTK3 PF12243.8 CEP11849.1 - 6.3e-30 103.7 0.1 1e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 CEP11849.1 - 5e-17 61.8 7.8 1.2e-16 60.6 7.8 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTD_bind PF04818.13 CEP11849.1 - 0.00013 22.7 0.0 0.00035 21.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DnaB_2 PF07261.11 CEP11849.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.6 3 0 0 3 3 3 0 Replication initiation and membrane attachment LRR_4 PF12799.7 CEP11850.1 - 5.1e-19 68.0 30.8 9.1e-05 22.8 0.2 6.0 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEP11850.1 - 1.1e-18 67.3 17.7 7.9e-11 41.8 1.9 3.4 1 1 2 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 CEP11850.1 - 2.3e-16 59.3 27.9 0.00038 20.2 7.6 5.4 3 2 2 5 5 5 5 Leucine rich repeat Imm51 PF15595.6 CEP11850.1 - 0.012 15.6 0.1 0.053 13.5 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 51 LRR_1 PF00560.33 CEP11850.1 - 1.9 9.4 26.0 23 6.0 0.1 8.1 5 2 1 6 6 6 0 Leucine Rich Repeat Rogdi_lz PF10259.9 CEP11851.1 - 5.7e-22 78.4 0.1 6.7e-21 74.9 0.1 1.9 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein bZIP_1 PF00170.21 CEP11852.1 - 6.9e-11 42.1 9.7 6.9e-11 42.1 9.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP11852.1 - 3.4e-08 33.4 7.3 3.4e-08 33.4 7.3 2.1 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP11852.1 - 0.036 14.6 5.7 0.11 13.0 5.7 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor GAS PF13851.6 CEP11852.1 - 0.1 11.9 6.5 0.21 10.9 6.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 CEP11852.1 - 0.36 11.5 3.1 0.35 11.5 1.1 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 CEP11852.1 - 0.49 10.6 6.2 0.92 9.7 6.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 MbeD_MobD PF04899.12 CEP11852.1 - 0.56 10.3 3.6 0.55 10.4 1.3 2.3 2 1 0 2 2 2 0 MbeD/MobD like GPI-anchored PF10342.9 CEP11853.1 - 1.5e-07 32.1 0.5 2.3e-07 31.5 0.5 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CEP11853.1 - 0.0094 15.7 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Big_6 PF17936.1 CEP11853.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig domain Sigma70_r4_2 PF08281.12 CEP11854.1 - 0.00059 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 CEP11854.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP11854.1 - 0.0085 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CEP11854.1 - 0.0098 16.5 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain DNA_pol_lambd_f PF10391.9 CEP11854.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HTH_7 PF02796.15 CEP11854.1 - 0.024 14.7 0.1 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 CEP11854.1 - 0.056 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DcpS PF05652.12 CEP11854.1 - 0.15 12.9 0.0 0.23 12.3 0.0 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal p450 PF00067.22 CEP11856.1 - 1e-74 252.0 0.4 2.9e-72 243.9 0.3 2.0 1 1 1 2 2 2 2 Cytochrome P450 PfkB PF00294.24 CEP11857.1 - 6.3e-13 48.7 0.0 1.4e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CEP11857.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase RL11D PF11088.8 CEP11857.1 - 0.042 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Peptidase_C48 PF02902.19 CEP11858.1 - 5.4e-43 147.3 1.0 7.6e-43 146.9 1.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ImcF-related_N PF14331.6 CEP11858.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain RNA_pol_Rpb2_6 PF00562.28 CEP11859.1 - 4e-128 427.8 0.0 5.9e-128 427.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEP11859.1 - 3.1e-66 222.7 0.1 4.7e-66 222.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CEP11859.1 - 9.4e-48 162.4 0.0 1.9e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CEP11859.1 - 2.6e-35 120.7 0.1 1.2e-34 118.6 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CEP11859.1 - 2e-25 88.8 0.1 4.6e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 CEP11859.1 - 1.2e-24 86.3 0.1 2.6e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 CEP11859.1 - 1.5e-22 79.9 0.7 5.1e-22 78.2 0.7 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF2318 PF10080.9 CEP11859.1 - 0.092 12.9 0.7 0.24 11.6 0.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_2 PF03107.16 CEP11859.1 - 1.4 9.3 3.2 8.7 6.8 3.2 2.2 1 1 0 1 1 1 0 C1 domain Comm PF15957.5 CEP11860.1 - 0.19 12.0 1.6 0.21 11.9 0.0 1.9 2 1 1 3 3 3 0 Commissureless DUF1765 PF08578.10 CEP11861.1 - 4.8e-23 82.0 6.4 4.8e-23 82.0 6.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) bZIP_2 PF07716.15 CEP11861.1 - 2.9e-08 33.7 9.3 2.9e-08 33.7 9.3 3.9 4 1 1 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP11861.1 - 3e-07 30.4 6.5 3e-07 30.4 6.5 3.3 2 1 1 3 3 3 1 bZIP transcription factor Sel1 PF08238.12 CEP11862.1 - 4.2e-19 68.6 8.4 8.9e-07 29.4 1.1 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 CEP11862.1 - 0.011 16.4 0.7 6 7.6 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP11862.1 - 0.058 14.1 0.4 1.4e+02 3.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt20 PF12090.8 CEP11863.1 - 2.1e-21 76.6 1.2 4e-12 46.3 1.1 13.2 3 2 5 8 8 8 2 Spt20 family SH3_1 PF00018.28 CEP11864.1 - 1.5e-07 30.9 1.4 3.2e-07 29.9 1.4 1.6 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 CEP11864.1 - 1.2e-06 28.7 0.3 1.2e-06 28.7 0.3 3.6 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CEP11864.1 - 5.1e-05 23.0 0.1 8.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP11864.1 - 0.0081 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ATG_C PF09333.11 CEP11864.1 - 0.017 15.5 0.3 0.017 15.5 0.3 2.2 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain FolB PF02152.18 CEP11864.1 - 0.17 12.4 0.8 0.43 11.1 0.3 1.9 2 0 0 2 2 2 0 Dihydroneopterin aldolase YEATS PF03366.16 CEP11865.1 - 2.7e-36 123.4 1.2 4e-36 122.9 1.2 1.3 1 0 0 1 1 1 1 YEATS family LSM PF01423.22 CEP11866.1 - 4e-22 77.7 0.2 4.4e-22 77.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain CLPTM1 PF05602.12 CEP11867.1 - 2.8e-149 497.8 0.0 3.6e-149 497.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 CEP11867.1 - 0.0045 17.3 3.4 0.018 15.4 3.4 2.0 1 0 0 1 1 1 1 2TM domain PQ-loop PF04193.14 CEP11867.1 - 0.026 14.3 0.6 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 PQ loop repeat AAA PF00004.29 CEP11868.1 - 1.1e-42 145.5 0.0 3e-42 144.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CEP11868.1 - 1.3e-27 95.6 0.4 8.7e-27 92.9 0.1 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CEP11868.1 - 2.5e-19 69.1 7.1 2.5e-19 69.1 7.1 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CEP11868.1 - 8.9e-09 35.0 0.1 3.2e-08 33.2 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 CEP11868.1 - 8.4e-06 26.3 0.2 0.00014 22.3 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CEP11868.1 - 3.2e-05 23.9 0.0 0.00015 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP11868.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEP11868.1 - 6.8e-05 23.2 0.1 0.035 14.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEP11868.1 - 0.00027 21.3 0.2 0.023 15.1 0.0 3.3 3 1 1 4 4 4 1 RNA helicase IstB_IS21 PF01695.17 CEP11868.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 CEP11868.1 - 0.00037 19.7 0.0 0.0031 16.7 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CEP11868.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP11868.1 - 0.0006 20.0 0.1 0.0055 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CEP11868.1 - 0.00076 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CEP11868.1 - 0.0015 19.1 0.1 0.0054 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CEP11868.1 - 0.0017 18.1 0.0 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CEP11868.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CEP11868.1 - 0.0069 16.0 1.0 0.9 9.1 0.1 3.2 3 1 0 4 4 4 1 AAA domain DUF3543 PF12063.8 CEP11868.1 - 0.018 14.4 0.6 0.029 13.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) AAA_17 PF13207.6 CEP11868.1 - 0.022 15.2 0.0 0.073 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 CEP11868.1 - 0.026 14.6 0.0 0.085 13.0 0.0 1.8 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.21 CEP11868.1 - 0.035 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CEP11868.1 - 0.038 13.9 0.5 1.5 8.6 0.0 2.8 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CEP11868.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 CEP11868.1 - 0.088 12.1 0.0 5.8 6.2 0.0 2.4 1 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 CEP11868.1 - 0.089 12.5 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 CEP11868.1 - 0.096 12.2 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CEP11868.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 CEP11868.1 - 0.13 12.1 0.0 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 NACHT domain EF-1_beta_acid PF10587.9 CEP11868.1 - 0.53 10.8 3.1 0.48 10.9 0.4 2.3 2 0 0 2 2 1 0 Eukaryotic elongation factor 1 beta central acidic region HORMA PF02301.18 CEP11869.1 - 1.1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 CEP11869.1 - 0.00064 19.7 0.5 0.0043 17.0 0.5 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF5123 PF17161.4 CEP11870.1 - 0.15 13.2 3.0 0.21 12.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5123) DUF1674 PF07896.12 CEP11871.1 - 0.078 13.5 0.9 0.21 12.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) Neur_chan_memb PF02932.16 CEP11871.1 - 0.12 12.4 6.6 0.15 12.1 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4724 PF15852.5 CEP11871.1 - 0.36 11.3 5.3 0.79 10.2 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) DDHD PF02862.17 CEP11871.1 - 0.6 10.2 8.2 0.79 9.8 8.2 1.3 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 CEP11871.1 - 0.94 9.4 22.5 1.1 9.2 22.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2877 PF11392.8 CEP11871.1 - 1.1 10.0 3.8 1.3 9.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2877) ABC2_membrane_3 PF12698.7 CEP11871.1 - 1.9 7.5 11.6 2.2 7.3 11.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 CEP11871.1 - 2.2 7.4 3.9 2.5 7.2 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2681 PF10883.8 CEP11871.1 - 2.7 8.4 22.4 2 8.9 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) Suf PF05843.14 CEP11871.1 - 4.1 7.3 13.9 5.1 7.0 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FSA_C PF10479.9 CEP11872.1 - 0.43 8.6 9.3 0.6 8.2 9.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 CEP11872.1 - 3.9 5.9 7.7 5.9 5.3 7.7 1.2 1 0 0 1 1 1 0 Macoilin family Alpha_GJ PF03229.13 CEP11872.1 - 8.2 7.0 11.6 15 6.1 11.6 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J rve PF00665.26 CEP11874.1 - 3.4e-12 46.6 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP11874.1 - 4.4e-12 45.9 0.0 4.2e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEP11874.1 - 2.7e-11 43.4 0.0 7e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP11874.1 - 6.1e-06 26.5 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP11875.1 - 1.4e-17 64.0 0.1 1.8e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3_N PF09440.10 CEP11876.1 - 1.3e-49 168.0 5.4 1.3e-49 168.0 5.4 3.1 3 1 1 4 4 4 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CEP11876.1 - 3.7e-16 59.5 0.7 6.9e-15 55.5 0.2 2.6 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CEP11876.1 - 0.0062 16.5 4.2 0.029 14.3 0.1 2.8 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 CEP11876.1 - 0.014 15.1 0.3 0.037 13.7 0.0 1.9 2 1 0 2 2 2 0 26S proteasome subunit RPN7 DUF2683 PF10884.8 CEP11876.1 - 0.055 13.7 2.8 0.44 10.8 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) SecA_SW PF07516.13 CEP11876.1 - 0.15 12.1 7.4 1.6 8.7 0.8 3.1 2 2 0 3 3 3 0 SecA Wing and Scaffold domain UvrB PF12344.8 CEP11876.1 - 0.18 11.7 1.1 6.5 6.7 0.1 2.8 2 0 0 2 2 2 0 Ultra-violet resistance protein B MFS_2 PF13347.6 CEP11877.1 - 2.5e-07 29.6 16.7 0.00015 20.5 4.4 3.9 3 1 0 3 3 3 3 MFS/sugar transport protein DUF485 PF04341.12 CEP11877.1 - 0.057 13.4 0.4 0.057 13.4 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 TMEM132D_C PF15706.5 CEP11877.1 - 0.14 12.0 0.3 4.5 7.1 0.5 2.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pyr_redox_2 PF07992.14 CEP11878.1 - 2.2e-69 233.9 6.3 2.2e-69 233.9 6.3 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEP11878.1 - 1.2e-41 141.4 0.4 6.8e-41 139.0 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEP11878.1 - 4.4e-19 68.8 8.2 3.4e-17 62.8 1.9 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP11878.1 - 5.9e-13 48.7 4.9 1.3e-09 37.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP11878.1 - 8.4e-12 44.9 5.9 1.5e-10 40.8 0.7 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CEP11878.1 - 1.7e-11 44.1 11.6 2.9e-11 43.4 0.2 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP11878.1 - 3.9e-09 36.1 15.1 1.8e-07 30.6 0.9 4.5 3 1 2 5 5 5 2 FAD binding domain Thi4 PF01946.17 CEP11878.1 - 9.6e-08 31.6 3.2 1.6e-05 24.3 0.0 2.5 2 1 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CEP11878.1 - 1.4e-06 28.4 3.1 0.0005 20.2 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CEP11878.1 - 2.6e-06 26.9 9.0 0.0081 15.4 0.3 3.6 3 1 0 3 3 3 3 FAD binding domain HI0933_like PF03486.14 CEP11878.1 - 5e-06 25.5 13.4 0.00014 20.7 0.5 4.1 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 CEP11878.1 - 7.6e-05 22.0 0.2 0.13 11.3 0.1 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CEP11878.1 - 0.00039 19.8 6.4 0.006 15.9 1.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CEP11878.1 - 0.022 14.4 15.1 0.17 11.4 0.1 4.0 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CEP11878.1 - 0.028 14.3 0.9 0.028 14.3 0.9 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CEP11878.1 - 0.34 11.4 1.4 7.1 7.1 0.3 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CEP11878.1 - 0.59 9.1 4.8 1.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 CEP11878.1 - 0.69 9.5 5.8 0.29 10.7 1.4 2.5 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Skp1_POZ PF03931.15 CEP11879.1 - 1.2e-09 38.2 0.1 2.8e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CEP11879.1 - 0.0047 17.1 0.0 0.0069 16.6 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain GerPB PF10803.8 CEP11880.1 - 0.45 10.6 0.0 0.45 10.6 0.0 2.8 4 0 0 4 4 4 0 Spore germination GerPB Linocin_M18 PF04454.12 CEP11881.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase ESSS PF10183.9 CEP11882.1 - 1.1e-09 38.5 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Na_trans_assoc PF06512.13 CEP11885.1 - 0.047 14.0 1.0 0.061 13.6 1.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DNA_pol3_delta2 PF13177.6 CEP11885.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit RsfS PF02410.15 CEP11886.1 - 2.1e-25 89.0 0.0 3.5e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Bromodomain PF00439.25 CEP11887.1 - 3.9e-18 65.3 0.2 1.1e-17 63.9 0.2 1.8 1 0 0 1 1 1 1 Bromodomain SWC7 PF17330.2 CEP11887.1 - 0.34 11.0 4.4 0.18 11.9 0.6 2.5 3 0 0 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 YEATS PF03366.16 CEP11888.1 - 3.3e-23 81.4 0.5 8.1e-23 80.2 0.5 1.7 1 0 0 1 1 1 1 YEATS family ESP PF16590.5 CEP11888.1 - 0.92 9.8 3.5 42 4.5 0.2 3.6 3 0 0 3 3 3 0 Exocrine gland-secreting peptide RasGEF PF00617.19 CEP11889.1 - 1.7e-14 54.4 0.1 1.7e-14 54.4 0.1 2.2 3 0 0 3 3 3 1 RasGEF domain DUF883 PF05957.13 CEP11889.1 - 0.03 14.9 0.1 0.14 12.7 0.1 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PRCH PF03967.13 CEP11889.1 - 4.7 7.4 8.0 0.38 11.0 0.9 2.8 2 1 2 4 4 4 0 Photosynthetic reaction centre, H-chain N-terminal region tRNA-synt_1g PF09334.11 CEP11890.1 - 1.5e-103 346.6 1.4 1e-102 343.8 1.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEP11890.1 - 1.4e-26 92.9 6.8 8.6e-13 47.4 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CEP11890.1 - 5.1e-14 52.3 0.9 1.4e-08 34.5 0.4 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CEP11890.1 - 1.1e-07 31.9 0.2 2.5e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DALR_1 PF05746.15 CEP11890.1 - 0.054 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 DALR anticodon binding domain AstB PF04996.12 CEP11890.1 - 0.096 11.3 0.0 3.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Succinylarginine dihydrolase F-box-like PF12937.7 CEP11891.1 - 4.7e-05 23.2 0.2 0.0021 17.9 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP11891.1 - 0.028 14.3 0.0 0.33 10.9 0.0 2.7 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 CEP11891.1 - 0.074 13.1 0.1 42 4.5 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat TPR_1 PF00515.28 CEP11893.1 - 1.7e-12 46.6 0.2 9.3e-05 22.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.24 CEP11893.1 - 8.5e-11 41.6 1.2 2.1e-10 40.4 1.2 1.6 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 CEP11893.1 - 4.1e-09 35.9 0.1 0.035 14.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11893.1 - 0.00025 21.0 0.1 3.4 8.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11893.1 - 0.0022 17.7 0.0 0.024 14.3 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 CEP11893.1 - 0.0094 16.2 0.0 5.5 7.4 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11893.1 - 0.016 15.8 0.0 1.1 9.9 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Ubiquitin_2 PF14560.6 CEP11893.1 - 0.082 13.4 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain TPR_9 PF13371.6 CEP11893.1 - 0.12 12.6 1.4 10 6.4 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CEP11894.1 - 3e-58 197.2 0.0 4.6e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11894.1 - 1.1e-27 97.0 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP11894.1 - 5.3e-06 27.1 0.4 2.9e-05 24.7 0.4 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 CEP11894.1 - 0.00041 20.0 0.2 0.87 9.2 0.0 3.6 4 0 0 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 CEP11894.1 - 0.015 15.3 4.6 0.16 12.0 4.6 2.7 1 1 0 1 1 1 0 PX domain Kinase-like PF14531.6 CEP11894.1 - 0.02 14.2 0.0 0.062 12.6 0.0 1.8 1 0 0 1 1 1 0 Kinase-like DNA_pol_A_exo1 PF01612.20 CEP11895.1 - 1.2e-11 44.7 0.0 3.2e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease HA2 PF04408.23 CEP11897.1 - 6.2e-18 65.1 0.0 6.2e-18 65.1 0.0 3.2 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP11897.1 - 7.7e-15 55.2 0.4 3.3e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEP11897.1 - 4.5e-08 33.3 0.2 1.5e-07 31.7 0.1 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold A_thal_3526 PF09713.10 CEP11897.1 - 0.02 15.1 0.5 0.085 13.1 0.5 2.1 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) LSDAT_euk PF18139.1 CEP11897.1 - 0.1 11.9 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 SLOG in TRPM Pantoate_ligase PF02569.15 CEP11898.1 - 4.4e-87 291.7 0.0 6.1e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase EF-hand_13 PF17958.1 CEP11898.1 - 1.1e-13 50.8 0.2 4e-13 49.0 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CEP11898.1 - 2.5e-05 24.6 0.2 0.00051 20.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair FAD_binding_3 PF01494.19 CEP11899.1 - 5e-27 95.1 0.0 6.2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEP11899.1 - 3.9e-09 36.6 5.0 0.00083 19.0 4.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP11899.1 - 2.6e-08 33.5 0.7 1.9e-05 24.1 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP11899.1 - 7.5e-07 29.3 0.4 1.8e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEP11899.1 - 1.3e-06 27.8 2.8 2.6e-06 26.8 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CEP11899.1 - 7.3e-06 26.5 5.0 0.00059 20.3 2.3 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEP11899.1 - 1.2e-05 24.3 0.5 0.014 14.2 0.8 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 CEP11899.1 - 0.00031 19.6 1.8 0.00073 18.4 1.2 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 CEP11899.1 - 0.00049 19.3 1.7 0.0005 19.3 0.7 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CEP11899.1 - 0.00052 19.4 0.9 0.0073 15.6 0.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CEP11899.1 - 0.00074 18.9 0.2 0.017 14.4 0.4 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 CEP11899.1 - 0.00089 18.7 4.0 0.0034 16.8 4.6 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CEP11899.1 - 0.0069 15.5 0.9 0.049 12.7 0.9 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CEP11899.1 - 0.064 12.5 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 CEP11899.1 - 0.072 12.9 1.4 0.12 12.2 0.4 1.8 2 0 0 2 2 2 0 Rossmann-like domain NAD_binding_7 PF13241.6 CEP11899.1 - 0.2 12.1 0.3 0.43 11.1 0.1 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding Thi4 PF01946.17 CEP11899.1 - 0.44 9.8 1.7 0.76 9.0 1.7 1.3 1 0 0 1 1 1 0 Thi4 family Cupin_2 PF07883.11 CEP11900.1 - 5.6e-21 74.0 1.0 1.8e-17 62.8 0.2 2.5 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 CEP11900.1 - 1e-05 25.4 0.4 6.8e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 CEP11900.1 - 0.00059 19.5 0.0 0.11 12.2 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 CEP11900.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase MFS_1 PF07690.16 CEP11901.1 - 2e-35 122.4 39.0 2.1e-35 122.3 38.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GFA PF04828.14 CEP11902.1 - 3.2e-14 53.0 2.9 5.3e-14 52.3 2.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_12 PF11331.8 CEP11902.1 - 0.072 12.9 0.0 0.072 12.9 0.0 2.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain Fungal_trans PF04082.18 CEP11903.1 - 7.7e-31 107.1 0.0 7.7e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP11903.1 - 4.9e-06 26.6 9.5 1.3e-05 25.2 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Het-C PF07217.11 CEP11903.1 - 0.34 9.4 4.9 0.71 8.3 4.9 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3464 PF11947.8 CEP11903.1 - 2.4 7.9 6.8 7.8 6.2 6.8 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 FAA_hydrolase PF01557.18 CEP11904.1 - 1.6e-60 204.5 0.0 3.2e-60 203.5 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family PPR_2 PF13041.6 CEP11905.1 - 1.5e-40 137.1 2.9 4.5e-11 42.8 0.0 7.2 4 2 4 8 8 8 6 PPR repeat family PPR_3 PF13812.6 CEP11905.1 - 1.1e-33 115.1 4.0 2.5e-10 40.3 0.0 6.7 4 3 3 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 CEP11905.1 - 5.4e-30 101.5 1.7 2.6e-07 30.4 0.0 8.4 9 0 0 9 9 8 5 PPR repeat PPR_1 PF12854.7 CEP11905.1 - 5.9e-20 70.7 0.2 8.8e-07 28.5 0.0 7.5 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 CEP11905.1 - 1.2e-17 64.0 1.1 4.9e-08 32.6 0.1 3.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_MalT PF17874.1 CEP11905.1 - 0.00071 19.1 0.4 0.0026 17.2 0.2 2.1 2 0 0 2 2 2 1 MalT-like TPR region Vps39_1 PF10366.9 CEP11905.1 - 0.0065 16.7 0.8 0.09 13.1 0.0 3.0 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 BTAD PF03704.17 CEP11905.1 - 0.011 16.1 0.0 0.065 13.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain RPM2 PF08579.11 CEP11905.1 - 0.016 15.6 5.2 4.3 7.7 0.0 4.3 3 1 3 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 CEP11905.1 - 0.026 14.6 0.0 0.32 11.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat V-ATPase_H_N PF03224.14 CEP11905.1 - 0.042 13.1 5.9 0.042 13.1 0.9 2.8 3 1 0 3 3 3 0 V-ATPase subunit H DEAD PF00270.29 CEP11906.1 - 1.9e-44 151.5 0.0 7e-44 149.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP11906.1 - 2.4e-30 105.2 1.9 2.9e-27 95.2 0.1 3.8 4 0 0 4 4 4 2 Helicase conserved C-terminal domain CMS1 PF14617.6 CEP11906.1 - 0.0032 16.8 0.0 0.061 12.6 0.0 2.7 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CEP11906.1 - 0.0046 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit LRR_4 PF12799.7 CEP11906.1 - 1.9 9.0 4.6 7.1 7.2 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CNH PF00780.22 CEP11907.1 - 1.6e-08 34.5 0.1 0.0088 15.7 0.1 3.2 3 0 0 3 3 3 3 CNH domain BLACT_WH PF17778.1 CEP11908.1 - 5.4e-15 55.1 0.1 1.2e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 CEP11908.1 - 1.2e-12 48.2 1.0 3.5e-12 46.8 1.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CEP11908.1 - 0.00032 20.6 0.2 0.00051 20.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CEP11908.1 - 0.00033 20.2 0.8 0.00066 19.3 0.8 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CEP11908.1 - 0.056 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Kelch_2 PF07646.15 CEP11909.1 - 2.9e-08 33.4 5.2 1.3e-05 25.0 0.0 5.2 5 1 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CEP11909.1 - 1.7e-07 31.1 16.0 2.9e-06 27.2 0.1 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP11909.1 - 4.4e-07 30.0 13.0 0.026 14.8 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CEP11909.1 - 1.3e-06 28.5 18.5 0.054 13.8 0.3 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Podoplanin PF05808.11 CEP11909.1 - 0.004 17.3 0.1 0.026 14.6 0.1 2.2 2 0 0 2 2 2 1 Podoplanin Kelch_5 PF13854.6 CEP11909.1 - 0.017 15.1 8.5 2 8.5 0.1 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 CEP11909.1 - 0.041 13.5 0.3 11 5.7 0.0 4.0 4 0 0 4 4 4 0 Kelch motif VSP PF03302.13 CEP11909.1 - 0.056 12.3 0.2 0.097 11.5 0.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.6 CEP11909.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DEAD PF00270.29 CEP11910.1 - 8.2e-42 142.9 0.0 2.2e-41 141.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP11910.1 - 1.1e-28 99.8 1.5 1.3e-27 96.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEP11910.1 - 0.0068 16.7 0.7 0.064 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Uds1 PF15456.6 CEP11910.1 - 0.37 11.0 13.5 0.3 11.3 10.4 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DUF2175 PF09943.9 CEP11910.1 - 1.6 9.0 6.2 8.3 6.8 6.2 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) EI24 PF07264.11 CEP11911.1 - 3.6e-22 79.5 10.9 5e-22 79.0 10.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) MWFE PF15879.5 CEP11911.1 - 0.14 12.3 0.3 0.41 10.9 0.3 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit F-box-like_2 PF13013.6 CEP11912.1 - 0.0085 16.0 1.2 0.013 15.5 1.2 1.4 1 1 0 1 1 1 1 F-box-like domain Coprogen_oxidas PF01218.18 CEP11914.1 - 3.6e-130 433.0 0.0 4e-130 432.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SRF-TF PF00319.18 CEP11915.1 - 6.2e-22 76.8 0.1 9.2e-22 76.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-RVT PF13966.6 CEP11916.1 - 5.9e-06 26.9 1.2 1.3e-05 25.8 1.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP11917.1 - 6.3e-23 81.5 0.0 1.5e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_39 PF14090.6 CEP11918.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.23 CEP11919.1 - 3e-31 108.6 3.9 5.5e-29 101.1 3.9 2.2 1 1 0 1 1 1 1 Kinesin motor domain Cep57_CLD_2 PF14197.6 CEP11919.1 - 0.0022 18.0 1.7 0.0022 18.0 1.7 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Hydrolase_6 PF13344.6 CEP11919.1 - 0.094 12.8 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Spc24 PF08286.11 CEP11919.1 - 5 7.4 9.4 6.3 7.1 1.6 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Usp PF00582.26 CEP11923.1 - 6.9e-23 81.7 0.5 4.3e-22 79.1 0.5 1.8 1 1 0 1 1 1 1 Universal stress protein family Pkinase PF00069.25 CEP11924.1 - 4e-70 236.2 0.0 6.3e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11924.1 - 1.5e-49 168.6 0.0 2.5e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP11924.1 - 2.2e-22 79.1 1.2 1.7e-21 76.4 0.0 2.8 3 0 0 3 3 3 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CEP11924.1 - 1.3e-06 27.5 1.8 3.5e-06 26.0 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CEP11924.1 - 1.1e-05 24.9 0.1 2.8e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP11924.1 - 0.003 16.9 0.1 0.0079 15.6 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP11924.1 - 0.042 13.8 0.0 1.6 8.6 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CEP11924.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HhH-GPD PF00730.25 CEP11925.1 - 6.4e-14 52.3 0.0 1.5e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.6 CEP11925.1 - 0.025 15.1 0.1 0.083 13.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) DUF1786 PF08735.10 CEP11925.1 - 0.076 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) HMG14_17 PF01101.18 CEP11925.1 - 4.3 8.4 9.0 2.2 9.3 6.2 1.9 2 0 0 2 2 2 0 HMG14 and HMG17 UCH PF00443.29 CEP11926.1 - 4.3e-62 209.9 0.0 8.5e-62 209.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.21 CEP11926.1 - 2.4e-32 111.0 34.5 4.1e-22 78.3 14.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C UCH_1 PF13423.6 CEP11926.1 - 5.6e-21 75.5 0.0 3.4e-19 69.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 CEP11926.1 - 7.2e-13 48.7 1.7 1.4e-12 47.8 1.7 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 CEP11926.1 - 4.8e-06 27.0 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CEP11926.1 - 0.22 11.3 0.6 0.57 10.0 0.6 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Helo_like_N PF17111.5 CEP11926.1 - 0.31 10.4 2.2 0.5 9.7 2.2 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins CENP-B_dimeris PF09026.10 CEP11927.1 - 0.49 10.8 18.6 1.4 9.3 13.0 2.8 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Androgen_recep PF02166.16 CEP11927.1 - 0.89 8.3 15.8 2.2 7.0 5.6 3.1 3 0 0 3 3 3 0 Androgen receptor Epimerase PF01370.21 CEP11928.1 - 1.1e-40 139.7 0.5 5e-40 137.5 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEP11928.1 - 4.2e-14 52.7 1.2 1.1e-08 34.8 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CEP11928.1 - 0.0014 17.8 0.0 0.0033 16.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CEP11928.1 - 0.0062 15.7 0.4 0.34 10.0 0.4 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein GRDA PF04723.14 CEP11928.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A TRAF6_Z2 PF18048.1 CEP11930.1 - 0.00074 19.6 2.7 0.0018 18.3 2.7 1.6 1 0 0 1 1 1 1 TNF receptor-associated factor 6 zinc finger 2 UIM PF02809.20 CEP11930.1 - 0.0052 16.6 2.1 0.0052 16.6 2.1 2.4 2 0 0 2 2 2 1 Ubiquitin interaction motif Rad50_zn_hook PF04423.14 CEP11930.1 - 0.034 14.0 0.1 0.034 14.0 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif PBP1_TM PF14812.6 CEP11930.1 - 7.7 7.0 9.2 0.94 9.9 2.5 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ELMO_CED12 PF04727.13 CEP11931.1 - 2.2e-42 145.2 2.1 3.3e-42 144.6 2.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family HpaP PF09483.10 CEP11931.1 - 0.058 13.7 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF1115 PF06544.12 CEP11932.1 - 1.7e-10 41.2 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) SPOB_ab PF14682.6 CEP11932.1 - 0.079 13.0 0.2 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Sec1 PF00995.23 CEP11933.1 - 1.3e-125 420.9 0.0 1.6e-125 420.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family P4Ha_N PF08336.11 CEP11933.1 - 0.12 12.4 0.0 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CAP_N PF01213.19 CEP11933.1 - 0.27 10.7 0.9 0.49 9.8 0.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UL42 PF17638.2 CEP11933.1 - 0.48 10.4 2.1 0.88 9.6 2.1 1.3 1 0 0 1 1 1 0 HCMV UL42 GATA PF00320.27 CEP11934.1 - 1.1e-29 101.7 15.2 1.2e-15 56.8 4.0 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CEP11934.1 - 5.2e-12 45.4 2.3 1.7e-11 43.8 2.3 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 CEP11934.1 - 0.00012 22.2 1.4 0.28 11.3 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEP11934.1 - 0.001 18.6 5.8 0.17 11.4 0.5 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Tis11B_N PF04553.12 CEP11934.1 - 0.0033 17.9 2.1 0.0033 17.9 2.1 3.3 4 0 0 4 4 4 1 Tis11B like protein, N terminus PEHE PF15275.6 CEP11934.1 - 0.04 14.5 0.5 0.04 14.5 0.5 4.5 3 2 1 4 4 4 0 PEHE domain zf-CHY PF05495.12 CEP11934.1 - 0.064 13.8 2.7 1.4 9.5 0.3 2.6 1 1 1 2 2 2 0 CHY zinc finger eIF-5_eIF-2B PF01873.17 CEP11934.1 - 0.21 11.4 4.2 9.2 6.2 0.3 3.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CEP11934.1 - 0.23 11.6 5.0 7.9 6.7 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-B_box PF00643.24 CEP11934.1 - 0.36 11.0 6.3 21 5.3 0.0 3.9 4 0 0 4 4 4 0 B-box zinc finger FYVE PF01363.21 CEP11934.1 - 0.36 11.0 3.1 2.6 8.3 0.2 2.9 3 0 0 3 3 3 0 FYVE zinc finger DZR PF12773.7 CEP11934.1 - 0.51 10.4 9.7 19 5.4 10.3 2.9 1 1 1 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 CEP11934.1 - 0.73 9.3 8.8 3.9 6.9 0.3 3.8 1 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FAM163 PF15069.6 CEP11934.1 - 0.84 10.1 8.4 0.48 10.9 0.6 3.2 1 1 1 2 2 2 0 FAM163 family Nudix_N_2 PF14803.6 CEP11934.1 - 4 7.5 7.4 24 4.9 0.0 3.4 3 1 1 4 4 4 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 CEP11934.1 - 5.8 6.8 7.5 13 5.6 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain ZF-HD_dimer PF04770.12 CEP11934.1 - 7 7.1 6.8 7.7 6.9 0.2 3.3 3 0 0 3 3 3 0 ZF-HD protein dimerisation region AMP-binding PF00501.28 CEP11935.1 - 3.7e-42 144.4 0.0 1.1e-41 142.9 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CEP11935.1 - 2.3e-36 125.3 0.0 1.7e-34 119.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.25 CEP11935.1 - 4.3e-09 36.6 0.1 1.3e-08 35.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CEP11935.1 - 5.3e-05 22.8 0.0 0.00022 20.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fe_hyd_SSU PF02256.17 CEP11935.1 - 0.11 12.5 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Iron hydrogenase small subunit DnaJ PF00226.31 CEP11936.1 - 4.4e-21 74.8 5.1 4.4e-21 74.8 5.1 3.1 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 CEP11936.1 - 6.7e-21 72.7 5.6 0.02 15.0 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 CEP11936.1 - 1e-19 70.5 0.1 3.4e-05 23.9 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEP11936.1 - 2.7e-19 68.1 9.3 0.04 13.8 0.1 7.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11936.1 - 3.5e-17 62.8 0.5 0.0003 21.4 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11936.1 - 1.7e-14 54.1 9.3 1.4e-05 25.5 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11936.1 - 3.3e-13 49.0 3.1 0.0056 17.0 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11936.1 - 3.8e-13 48.5 7.7 0.35 11.2 0.1 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP11936.1 - 2.7e-12 46.4 2.1 0.0083 16.9 0.0 5.7 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11936.1 - 3.2e-12 45.9 5.1 3.3e-05 23.5 0.1 5.6 5 1 1 6 6 6 2 TPR repeat ANAPC3 PF12895.7 CEP11936.1 - 2.5e-08 34.0 12.6 0.0055 16.9 0.1 5.4 3 1 3 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEP11936.1 - 1.9e-06 28.2 5.2 0.55 11.0 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11936.1 - 4.1e-05 23.8 6.2 2.8 8.3 0.0 5.3 4 3 1 5 5 5 1 Tetratricopeptide repeat DUF4398 PF14346.6 CEP11936.1 - 0.00034 21.2 6.4 0.12 13.0 0.5 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4398) TPR_20 PF14561.6 CEP11936.1 - 0.00057 20.2 6.6 0.056 13.8 0.0 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP11936.1 - 0.012 15.6 2.3 39 4.6 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP11936.1 - 0.016 15.3 2.2 25 5.0 0.1 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.13 CEP11936.1 - 0.016 15.3 3.7 5.7 7.1 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF357) BTAD PF03704.17 CEP11936.1 - 0.059 13.8 1.3 9.6 6.6 0.0 3.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain HemY_N PF07219.13 CEP11936.1 - 0.07 13.3 4.4 11 6.3 0.0 3.7 3 1 0 4 4 4 0 HemY protein N-terminus CotJB PF12652.7 CEP11936.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.3 3 1 0 3 3 3 0 CotJB protein TPR_10 PF13374.6 CEP11936.1 - 0.34 10.8 3.1 6.9 6.7 0.2 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CEP11936.1 - 1.2 9.6 5.1 11 6.5 0.2 3.5 3 1 2 5 5 4 0 Alkyl sulfatase dimerisation SPT16 PF08644.11 CEP11936.1 - 2.2 8.4 7.4 0.7 10.1 0.2 2.8 2 1 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) CAP PF00188.26 CEP11937.1 - 4.1e-23 82.6 8.7 1.5e-22 80.7 8.7 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF1690 PF07956.11 CEP11938.1 - 9e-23 81.2 9.8 9e-23 81.2 9.8 3.3 3 0 0 3 3 3 1 Protein of Unknown function (DUF1690) PRKCSH PF07915.13 CEP11938.1 - 6.9e-15 55.8 2.8 6.9e-15 55.8 2.8 2.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF4041 PF13250.6 CEP11938.1 - 0.11 12.4 0.7 21 5.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Hira PF07569.11 CEP11939.1 - 3.3e-61 206.8 0.1 9.3e-61 205.4 0.1 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 CEP11939.1 - 3.9e-29 100.3 18.1 2e-07 31.5 0.3 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11939.1 - 3.5e-14 52.9 2.3 0.13 12.5 0.0 7.1 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CEP11939.1 - 1.2e-09 37.8 0.5 4e-09 36.1 0.5 2.0 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 CEP11939.1 - 0.00074 18.6 0.6 0.56 9.1 0.0 4.2 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEP11939.1 - 0.023 14.6 3.2 3.8 7.6 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat LRR_8 PF13855.6 CEP11940.1 - 2e-15 56.3 20.3 7e-10 38.5 4.5 3.7 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEP11940.1 - 7.9e-09 35.7 25.5 0.00072 19.9 1.5 3.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP11940.1 - 0.01 16.3 19.0 2.8 8.9 0.1 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat PARM PF17061.5 CEP11940.1 - 0.34 11.0 14.4 0.71 10.0 14.4 1.4 1 0 0 1 1 1 0 PARM LRR_6 PF13516.6 CEP11940.1 - 9.1 6.6 16.3 2.8 8.2 0.5 4.0 4 0 0 4 4 4 0 Leucine Rich repeat MAPEG PF01124.18 CEP11941.1 - 0.0048 16.8 7.0 0.0094 15.8 7.0 1.5 1 1 1 2 2 2 1 MAPEG family Aminotran_5 PF00266.19 CEP11942.1 - 1.9e-29 102.8 0.0 2.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 CEP11942.1 - 0.00058 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain KR PF08659.10 CEP11942.1 - 0.012 15.5 0.3 0.023 14.6 0.0 1.6 2 0 0 2 2 2 0 KR domain Pyr_redox_2 PF07992.14 CEP11943.1 - 7.3e-34 117.3 0.3 8.3e-34 117.1 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP11943.1 - 6.2e-13 49.1 0.6 4.9e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP11943.1 - 4.8e-08 32.6 0.5 1.7e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP11943.1 - 3.6e-07 30.1 0.1 0.012 15.2 0.1 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP11943.1 - 5e-07 29.8 0.2 0.013 15.4 0.1 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 CEP11943.1 - 5.6e-06 25.7 0.2 0.00017 20.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CEP11943.1 - 0.00012 21.1 0.3 0.014 14.3 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 CEP11943.1 - 0.00053 20.2 1.2 0.1 12.9 0.1 2.8 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.6 CEP11943.1 - 0.00068 20.0 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CEP11943.1 - 0.0028 17.8 0.6 0.08 13.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CEP11943.1 - 0.0038 16.3 0.3 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 CEP11943.1 - 0.0049 17.1 1.2 3.5 7.9 0.3 2.6 2 1 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain PRMT5 PF05185.16 CEP11943.1 - 0.02 14.7 0.1 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase FAD_binding_3 PF01494.19 CEP11943.1 - 0.13 11.5 2.3 9.8 5.3 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 CEP11943.1 - 0.13 11.3 1.7 20 4.1 1.8 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pkinase_Tyr PF07714.17 CEP11944.1 - 2.3e-20 73.0 0.4 9.1e-20 71.0 0.4 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEP11944.1 - 4.7e-19 68.8 0.2 9.8e-19 67.7 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain SAP PF02037.27 CEP11944.1 - 0.00018 21.2 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain RhoGEF PF00621.20 CEP11945.1 - 6e-35 121.1 4.4 6e-35 121.1 4.4 2.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 CEP11945.1 - 2.7e-05 24.6 0.7 0.00011 22.7 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 CEP11945.1 - 0.11 12.8 0.1 0.46 10.8 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 CEP11945.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain DUF3808 PF10300.9 CEP11946.1 - 1.2e-54 185.9 12.4 7.3e-30 104.1 0.4 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) Med30 PF11315.8 CEP11946.1 - 0.04 14.1 4.1 0.41 10.8 0.2 2.7 2 1 0 2 2 2 0 Mediator complex subunit 30 TPR_2 PF07719.17 CEP11946.1 - 0.065 13.4 8.4 0.17 12.1 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP11946.1 - 0.24 12.1 0.3 0.24 12.1 0.3 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP11946.1 - 5.5 7.0 6.2 3.9 7.5 0.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_3 PF13358.6 CEP11947.1 - 8.2e-20 71.0 0.4 7.5e-19 67.9 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease Terminase_5 PF06056.12 CEP11947.1 - 0.15 11.9 0.6 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Metallophos PF00149.28 CEP11948.1 - 1.1e-39 137.1 0.3 1.5e-39 136.7 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP11948.1 - 0.00067 20.0 0.2 0.0014 19.0 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CEP11948.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 CEP11948.1 - 0.037 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF3759 PF12585.8 CEP11949.1 - 4.6e-36 122.7 9.4 5.4e-36 122.5 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) AA_permease_2 PF13520.6 CEP11951.1 - 3.4e-53 181.0 51.1 2.2e-49 168.5 32.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 CEP11951.1 - 3.4e-19 68.8 53.8 1.7e-17 63.2 53.8 2.7 1 1 0 1 1 1 1 Amino acid permease OST3_OST6 PF04756.13 CEP11951.1 - 5.1 6.3 10.7 0.098 12.0 3.1 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Abhydrolase_3 PF07859.13 CEP11952.1 - 1.8e-26 93.3 0.0 2.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP11952.1 - 6.7e-13 48.2 0.2 1.2e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_transf_41 PF13844.6 CEP11953.1 - 1.9e-111 372.8 19.0 4.6e-58 196.8 0.1 4.7 4 1 1 5 5 5 3 Glycosyl transferase family 41 TPR_1 PF00515.28 CEP11953.1 - 1.4e-20 72.2 4.8 7.2e-05 22.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP11953.1 - 9.5e-18 62.9 0.7 6.6e-06 25.9 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP11953.1 - 5.5e-17 60.4 3.2 0.0014 18.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP11953.1 - 1.3e-13 50.4 2.7 0.00026 20.6 0.0 5.7 3 1 2 5 5 5 3 TPR repeat TPR_10 PF13374.6 CEP11953.1 - 1.3e-13 50.3 8.2 0.002 17.9 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP11953.1 - 4.2e-13 48.7 5.1 0.019 15.3 0.0 6.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP11953.1 - 2.9e-09 37.1 9.8 0.084 13.2 0.0 5.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP11953.1 - 5.3e-08 33.0 0.1 0.28 12.1 0.0 5.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP11953.1 - 1e-07 31.5 2.2 0.057 13.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP11953.1 - 7.5e-06 26.5 7.4 1.4e-05 25.6 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP11953.1 - 4.1e-05 24.0 2.0 0.016 15.7 0.0 4.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEP11953.1 - 0.00027 21.0 0.7 0.0035 17.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Flavodoxin_1 PF00258.25 CEP11953.1 - 0.046 13.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Flavodoxin TPR_6 PF13174.6 CEP11953.1 - 0.68 10.7 2.8 22 6.0 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 CEP11954.1 - 4.5e-64 217.2 17.8 3.5e-41 141.8 5.4 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family zf-C2H2 PF00096.26 CEP11955.1 - 2.6e-15 55.9 28.0 2.8e-07 30.6 5.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP11955.1 - 1e-10 41.5 19.9 9.3e-08 32.2 1.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP11955.1 - 4e-09 36.5 26.5 0.0022 18.7 1.8 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP11955.1 - 5.3e-06 26.3 16.7 0.0077 16.2 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP11955.1 - 0.00071 19.8 10.3 0.13 12.6 0.7 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CEP11955.1 - 0.0075 16.7 7.6 0.037 14.5 1.6 2.8 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger PTN13_u3 PF16599.5 CEP11955.1 - 0.042 13.9 3.1 0.065 13.3 3.1 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ zf-C2H2_11 PF16622.5 CEP11955.1 - 0.048 13.4 17.4 1.1 9.1 1.6 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 CEP11955.1 - 0.09 13.2 10.0 3.4 8.2 1.6 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SR-25 PF10500.9 CEP11955.1 - 0.091 12.4 5.1 0.14 11.8 5.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zn-ribbon_8 PF09723.10 CEP11955.1 - 0.1 12.7 8.1 0.59 10.3 1.7 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf_ZIC PF18366.1 CEP11955.1 - 0.27 11.4 4.0 20 5.4 0.1 3.3 2 1 1 3 3 3 0 Zic proteins zinc finger domain Ogr_Delta PF04606.12 CEP11955.1 - 0.37 10.8 7.1 12 6.0 0.0 2.8 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.7 CEP11955.1 - 0.56 10.3 4.7 1.5 8.9 4.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 CEP11955.1 - 1.5 8.8 16.0 0.93 9.5 1.3 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CEP11955.1 - 3 8.2 13.7 0.087 13.1 3.5 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 CEP11955.1 - 4.8 7.2 14.4 0.37 10.7 8.6 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Chromo_shadow PF01393.19 CEP11956.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Chromo shadow domain CDC45 PF02724.14 CEP11956.1 - 6 5.0 8.1 7.4 4.7 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DSPc PF00782.20 CEP11958.1 - 3.1e-11 43.2 0.0 5.5e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CEP11958.1 - 0.0016 18.7 0.1 0.004 17.4 0.1 1.6 2 0 0 2 2 2 1 Rit1 DUSP-like domain CDKN3 PF05706.12 CEP11958.1 - 0.019 14.6 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CEP11958.1 - 0.022 14.3 0.0 0.047 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEP11958.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Cellulase PF00150.18 CEP11959.1 - 7.3e-20 71.5 0.0 9.6e-13 48.2 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CEP11959.1 - 6.7e-16 58.6 0.1 1.5e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain ABC_tran PF00005.27 CEP11960.1 - 1.3e-33 116.5 0.3 1.5e-18 67.6 0.1 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEP11960.1 - 2e-11 44.2 0.1 0.0038 17.1 0.0 3.6 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP11960.1 - 3.2e-08 33.3 0.1 0.088 12.2 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CEP11960.1 - 8.1e-08 32.7 0.0 0.018 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEP11960.1 - 1.4e-07 31.6 0.9 0.00089 19.2 0.0 3.5 4 0 0 4 4 3 2 RsgA GTPase AAA PF00004.29 CEP11960.1 - 1.5e-07 31.9 0.6 0.06 13.8 0.0 4.5 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CEP11960.1 - 2.8e-07 31.3 0.6 0.031 14.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CEP11960.1 - 5.8e-07 29.2 0.1 0.02 14.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CEP11960.1 - 6e-07 29.8 0.0 0.39 11.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 CEP11960.1 - 1e-06 28.8 0.1 0.0045 17.1 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CEP11960.1 - 8.5e-06 26.3 0.1 0.032 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP11960.1 - 1.9e-05 25.1 0.0 0.04 14.3 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CEP11960.1 - 2.2e-05 24.8 0.2 0.52 10.7 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Chromo PF00385.24 CEP11960.1 - 2.6e-05 24.0 1.5 0.00026 20.8 0.3 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 CEP11960.1 - 2.8e-05 24.1 0.3 0.15 11.9 0.0 3.5 3 1 0 3 3 3 1 NACHT domain MeaB PF03308.16 CEP11960.1 - 8e-05 21.7 1.3 0.17 10.8 0.0 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 CEP11960.1 - 0.00016 21.4 0.1 0.31 10.8 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 CEP11960.1 - 0.00045 20.0 5.3 0.29 10.8 0.0 3.3 4 0 0 4 4 2 2 AAA ATPase domain DUF815 PF05673.13 CEP11960.1 - 0.00049 19.3 0.1 0.44 9.7 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Rad17 PF03215.15 CEP11960.1 - 0.0012 18.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 CEP11960.1 - 0.0019 18.4 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEP11960.1 - 0.0019 18.0 0.0 0.57 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 CEP11960.1 - 0.002 18.0 0.2 0.21 11.4 0.0 2.7 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 CEP11960.1 - 0.0024 18.0 2.2 0.2 11.7 0.0 3.1 4 0 0 4 4 2 1 Helicase HerA, central domain ATP-synt_ab PF00006.25 CEP11960.1 - 0.0043 16.7 0.0 0.61 9.7 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 CEP11960.1 - 0.0074 16.3 0.0 3.3 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP11960.1 - 0.0075 15.8 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CEP11960.1 - 0.0075 16.0 0.1 0.82 9.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 CEP11960.1 - 0.0086 15.7 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain 4HB PF17947.1 CEP11960.1 - 0.011 15.7 0.2 0.072 13.2 0.1 2.5 2 0 0 2 2 1 0 Four helical bundle domain NB-ARC PF00931.22 CEP11960.1 - 0.012 14.8 0.1 1.8 7.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 CEP11960.1 - 0.017 15.2 0.0 0.98 9.4 0.0 2.9 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 CEP11960.1 - 0.025 14.5 0.8 5.3 6.9 0.0 3.4 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CEP11960.1 - 0.028 13.7 0.1 9 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 CEP11960.1 - 0.036 13.8 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CEP11960.1 - 0.037 13.8 0.0 15 5.3 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CEP11960.1 - 0.046 13.6 0.1 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 CEP11960.1 - 0.051 13.1 0.3 5.4 6.5 0.0 3.3 4 0 0 4 4 3 0 Ferrous iron transport protein B HEAT PF02985.22 CEP11960.1 - 0.059 13.6 2.8 26 5.4 0.0 5.1 5 0 0 5 5 4 0 HEAT repeat PRK PF00485.18 CEP11960.1 - 0.064 13.0 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_13 PF13166.6 CEP11960.1 - 0.065 11.9 0.5 9 4.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CEP11960.1 - 0.079 13.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CEP11960.1 - 0.11 12.7 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CEP11960.1 - 0.18 11.8 0.5 16 5.5 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CEP11960.1 - 1 9.8 3.0 29 5.1 0.1 3.3 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CEP11961.1 - 4.1e-10 40.3 0.0 4.4e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.6 CEP11961.1 - 0.046 14.0 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ZoocinA_TRD PF16775.5 CEP11962.1 - 0.079 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme MFS_1 PF07690.16 CEP11963.1 - 7.4e-24 84.3 40.8 7.4e-24 84.3 40.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP11963.1 - 3.2e-11 42.8 6.1 3.2e-11 42.8 6.1 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEP11963.1 - 2.9e-06 26.0 19.2 6.3e-06 24.9 19.1 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CEP11963.1 - 0.0014 17.0 15.8 0.017 13.4 1.7 3.3 1 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Lactate_perm PF02652.14 CEP11964.1 - 8.3e-128 427.4 32.4 2e-77 261.1 19.9 2.1 2 0 0 2 2 2 2 L-lactate permease DUF5493 PF17597.2 CEP11964.1 - 0.026 14.8 0.6 0.026 14.8 0.6 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5493) DUF4199 PF13858.6 CEP11964.1 - 0.6 10.5 0.0 0.6 10.5 0.0 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF4199) MFS_1 PF07690.16 CEP11965.1 - 4.9e-21 75.0 27.8 1.7e-20 73.3 27.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily QCR10 PF09796.9 CEP11965.1 - 0.047 13.7 0.1 28 4.8 0.1 3.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Phage_holin_2_1 PF04971.12 CEP11965.1 - 1.7 8.7 4.6 0.51 10.4 0.8 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S RhoGAP PF00620.27 CEP11966.1 - 2.2e-33 115.2 0.2 3.6e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 CEP11966.1 - 2.2e-23 83.0 1.4 4.9e-23 81.8 0.3 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CEP11966.1 - 0.00071 19.3 0.5 0.0025 17.6 0.1 2.1 3 0 0 3 3 3 1 CRAL/TRIO domain DUF1819 PF08849.11 CEP11966.1 - 0.03 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) MitMem_reg PF13012.6 CEP11966.1 - 0.084 13.3 0.4 0.62 10.5 0.2 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Acetyltransf_11 PF13720.6 CEP11966.1 - 0.17 12.4 0.0 1.4 9.4 0.0 2.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ApoB100_C PF12491.8 CEP11966.1 - 0.18 11.8 1.8 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal tRNA-synt_2 PF00152.20 CEP11967.1 - 9.8e-82 274.5 0.5 1.4e-81 274.0 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEP11967.1 - 2.2e-05 24.4 0.4 4.6e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEP11967.1 - 0.011 15.2 0.4 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) POM121 PF15229.6 CEP11967.1 - 1.4 8.5 5.1 2 8.0 5.1 1.2 1 0 0 1 1 1 0 POM121 family PS_Dcarbxylase PF02666.15 CEP11968.1 - 1.1e-61 207.8 0.0 1.8e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CEP11968.1 - 5.3e-28 97.3 0.0 3.1e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain PRA1 PF03208.19 CEP11968.1 - 2.8e-26 91.9 3.1 5.1e-26 91.0 3.1 1.4 1 0 0 1 1 1 1 PRA1 family protein UBZ_FAAP20 PF15750.5 CEP11968.1 - 0.018 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DOCK-C2 PF14429.6 CEP11968.1 - 0.021 14.6 0.4 0.046 13.5 0.4 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins EF-hand_6 PF13405.6 CEP11968.1 - 0.033 14.1 0.1 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Y_phosphatase2 PF03162.13 CEP11969.1 - 1.3e-15 57.4 0.0 3.2e-12 46.3 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family WD40 PF00400.32 CEP11970.1 - 2.1e-17 63.2 18.2 0.00016 22.4 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP11970.1 - 4.4e-10 39.7 7.8 0.0024 18.1 0.1 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain VCBS PF13517.6 CEP11970.1 - 0.0018 18.9 0.8 17 6.1 0.0 4.5 5 0 0 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TFIIIC_delta PF12657.7 CEP11970.1 - 0.0027 17.7 10.9 0.029 14.3 0.3 2.9 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 CEP11970.1 - 0.003 16.6 3.1 4.5 6.1 0.1 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HepII_C PF18675.1 CEP11970.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Heparinase II C-terminal domain CPSase_L_D2 PF02786.17 CEP11971.1 - 3.6e-69 232.5 0.1 6.9e-69 231.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEP11971.1 - 6.8e-33 113.5 0.5 1.6e-32 112.3 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP11971.1 - 6.5e-32 109.9 0.0 1.4e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEP11971.1 - 7.6e-15 54.5 3.7 4e-14 52.2 1.4 3.0 4 0 0 4 4 4 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEP11971.1 - 3.5e-11 43.0 0.0 7.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEP11971.1 - 5.5e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEP11971.1 - 9e-09 35.0 2.0 6.6e-05 22.7 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CEP11971.1 - 2.9e-08 33.9 0.1 6.5e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 CEP11971.1 - 1.8e-05 25.4 3.8 0.015 16.0 0.0 3.8 4 0 0 4 4 4 2 HlyD family secretion protein HlyD_D23 PF16576.5 CEP11971.1 - 4e-05 22.9 0.1 0.00026 20.3 0.0 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 CEP11971.1 - 0.00079 19.3 1.2 0.0066 16.4 0.3 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 CEP11971.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon NQRA PF05896.11 CEP11971.1 - 0.006 16.1 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) LAL_C2 PF18603.1 CEP11971.1 - 0.1 12.8 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Pkinase PF00069.25 CEP11972.1 - 1.1e-76 257.7 0.0 1.4e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11972.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP11972.1 - 6.3e-06 25.7 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP11972.1 - 2.8e-05 23.1 0.0 6.5e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEP11972.1 - 0.0067 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEP11972.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 CEP11972.1 - 0.043 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3775 PF12616.8 CEP11972.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) FTA2 PF13095.6 CEP11972.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PACT_coil_coil PF10495.9 CEP11972.1 - 0.19 12.3 0.1 0.49 11.0 0.0 1.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein AAA_23 PF13476.6 CEP11973.1 - 0.55 10.7 13.4 0.093 13.2 6.4 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 CEP11974.1 - 4e-11 42.7 12.0 3.3e-05 24.1 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP11974.1 - 7.3e-07 29.3 14.4 0.0012 19.2 0.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP11974.1 - 6.8e-06 26.5 10.8 0.0087 16.8 3.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP11974.1 - 0.0025 17.8 7.4 0.0044 17.0 1.5 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CEP11974.1 - 0.0031 17.8 1.9 0.0056 16.9 1.9 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 CEP11974.1 - 0.0056 16.5 4.1 0.13 12.2 0.8 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type DUF3268 PF11672.8 CEP11974.1 - 0.0082 16.5 0.4 0.016 15.6 0.4 1.4 1 0 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 CEP11974.1 - 0.15 12.4 0.6 0.15 12.4 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 CEP11974.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 CEP11974.1 - 0.24 11.3 8.1 0.28 11.1 2.4 2.4 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-BED PF02892.15 CEP11974.1 - 0.35 10.9 0.2 0.35 10.9 0.2 2.9 3 1 0 3 3 2 0 BED zinc finger zf-met PF12874.7 CEP11974.1 - 0.37 11.3 5.2 0.15 12.5 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.7 CEP11974.1 - 1.4 8.9 4.1 2.9 7.9 4.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 CEP11974.1 - 1.8 8.4 7.1 0.68 9.7 1.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type PDZ_1 PF12812.7 CEP11975.1 - 2.7e-32 110.6 0.0 3.2e-23 81.5 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 CEP11975.1 - 8.5e-20 72.2 0.0 6.4e-16 59.6 0.0 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 CEP11975.1 - 2.1e-15 56.3 0.1 1e-05 25.3 0.0 4.7 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 CEP11975.1 - 1.7e-13 50.7 0.2 0.00061 20.1 0.0 4.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 CEP11975.1 - 1e-11 45.0 0.8 0.0004 20.7 0.1 4.1 4 0 0 4 4 4 2 PDZ domain Trypsin PF00089.26 CEP11975.1 - 0.0024 17.7 0.2 2 8.2 0.0 3.9 4 0 0 4 4 4 1 Trypsin Tricorn_PDZ PF14685.6 CEP11975.1 - 0.013 15.5 1.1 8.2 6.5 0.0 3.5 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 CEP11975.1 - 0.035 12.7 0.2 0.094 11.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase S46 MCR_beta_N PF02783.15 CEP11975.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Pkinase PF00069.25 CEP11976.1 - 1.5e-64 218.0 0.0 2.4e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP11976.1 - 9.6e-49 166.0 0.0 1.7e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CEP11976.1 - 2e-09 37.7 0.0 4.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 CEP11976.1 - 4.7e-07 29.4 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CEP11976.1 - 0.00048 19.0 0.0 0.001 17.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RA PF00788.23 CEP11976.1 - 0.043 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Kdo PF06293.14 CEP11976.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.23 CEP11977.1 - 1e-95 319.1 0.2 1.6e-95 318.5 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEP11977.1 - 1.2e-32 112.4 0.0 2.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CEP11977.1 - 2.3e-23 82.4 2.3 5.9e-23 81.1 2.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CEP11977.1 - 1.4e-15 57.8 0.0 5.3e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CEP11977.1 - 3.7e-08 33.0 0.1 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEP11977.1 - 0.00096 19.0 0.0 0.0048 16.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEP11977.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 CEP11977.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_Tnp_1_7 PF13843.6 CEP11978.1 - 1.7e-41 142.7 0.0 3e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 RhoGAP PF00620.27 CEP11978.1 - 3.3e-38 130.9 0.8 9.7e-38 129.4 0.8 1.8 1 0 0 1 1 1 1 RhoGAP domain DDE_5 PF13546.6 CEP11978.1 - 0.037 13.4 0.0 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CEP11978.1 - 0.075 12.7 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain HAMP PF00672.25 CEP11979.1 - 1.5e-165 537.6 61.4 7.5e-08 32.6 0.0 23.5 22 0 0 22 22 22 21 HAMP domain HATPase_c PF02518.26 CEP11979.1 - 8.6e-31 106.7 0.9 6.8e-30 103.9 0.2 3.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP11979.1 - 7.3e-26 90.5 0.2 9.4e-24 83.7 0.1 4.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CEP11979.1 - 1.4e-16 60.3 0.5 1.4e-16 60.3 0.5 4.4 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.17 CEP11979.1 - 6.4e-16 58.1 15.6 30 4.7 0.0 19.0 20 0 0 20 20 19 0 Helix-turn-helix domain, rpiR family DUF4279 PF14106.6 CEP11979.1 - 8.9e-07 29.1 0.0 19 5.5 0.0 11.1 19 0 0 19 19 17 0 Domain of unknown function (DUF4279) WXG100 PF06013.12 CEP11979.1 - 2.5e-06 27.6 59.2 0.17 12.1 0.0 18.1 19 1 1 20 20 20 1 Proteins of 100 residues with WXG SpoIIID PF12116.8 CEP11979.1 - 1.1e-05 25.5 36.5 13 6.0 0.0 16.0 19 0 0 19 19 18 0 Stage III sporulation protein D VHS PF00790.19 CEP11979.1 - 0.0078 16.1 0.1 0.069 13.0 0.1 2.8 1 0 0 1 1 1 1 VHS domain Vac_Fusion PF02346.16 CEP11979.1 - 0.011 15.3 5.0 2.1e+02 1.6 0.0 9.7 14 0 0 14 14 14 0 Chordopoxvirus multifunctional envelope protein A27 FlgN PF05130.12 CEP11979.1 - 0.051 14.1 8.3 17 5.9 2.1 8.0 12 0 0 12 12 11 0 FlgN protein DUF1759 PF03564.15 CEP11979.1 - 0.11 12.4 23.3 1.3e+02 2.5 0.0 13.0 17 0 0 17 17 17 0 Protein of unknown function (DUF1759) ApoLp-III PF07464.11 CEP11979.1 - 0.14 12.3 110.7 0.17 12.0 2.7 19.7 3 2 16 20 20 20 0 Apolipophorin-III precursor (apoLp-III) Jnk-SapK_ap_N PF09744.9 CEP11979.1 - 0.23 11.7 9.0 0.21 11.8 0.4 4.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3829 PF12889.7 CEP11979.1 - 7.5 5.9 50.0 4.9 6.5 0.4 14.1 4 3 11 20 20 20 0 Protein of unknown function (DUF3829) W2 PF02020.18 CEP11980.1 - 3.4e-20 72.0 11.5 1.4e-19 70.0 11.5 2.2 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CEP11980.1 - 8.4e-11 41.2 13.8 9.9e-06 25.1 2.4 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEP11980.1 - 6.2e-06 25.9 4.0 9.4e-06 25.3 0.6 2.5 1 1 1 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 CEP11980.1 - 4.5e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 CEP11980.1 - 0.0003 19.8 0.3 0.00061 18.8 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CEP11980.1 - 0.0076 14.4 1.1 0.016 13.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 CEP11980.1 - 0.011 16.1 0.0 0.12 12.7 0.0 2.3 3 0 0 3 3 3 0 MobA-like NTP transferase domain TFIIS_C PF01096.18 CEP11981.1 - 4.8e-17 61.5 2.0 4.8e-17 61.5 2.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF523 PF04463.12 CEP11981.1 - 1.3e-06 28.5 0.6 1.8e-06 28.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF523) RNA_POL_M_15KD PF02150.16 CEP11981.1 - 1.7e-06 27.8 16.2 0.00057 19.7 4.3 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit GATA PF00320.27 CEP11981.1 - 0.0085 15.7 6.4 0.5 10.0 0.1 3.1 3 1 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP11981.1 - 0.03 13.8 10.6 0.59 9.7 1.7 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 CEP11981.1 - 0.033 14.2 12.8 36 4.5 12.8 3.0 1 1 0 1 1 1 0 Double zinc ribbon zf-TFIIB PF13453.6 CEP11981.1 - 0.045 13.1 8.3 0.046 13.1 1.2 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1595 PF12760.7 CEP11981.1 - 0.049 13.6 10.0 0.077 13.0 1.9 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 CEP11981.1 - 0.05 13.3 1.5 0.05 13.3 1.5 2.8 3 1 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-IS66 PF13005.7 CEP11981.1 - 0.079 13.4 12.1 1.6 9.2 0.1 4.0 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF35_N PF12172.8 CEP11981.1 - 0.091 12.7 2.7 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.10 CEP11981.1 - 0.1 12.3 16.2 2.9 7.7 0.9 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain tRNA-synt_1f PF01921.18 CEP11981.1 - 0.11 11.4 0.8 0.14 11.1 0.8 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.10 CEP11981.1 - 0.14 12.3 14.6 2 8.6 0.0 4.0 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 CEP11981.1 - 0.14 11.9 18.1 0.47 10.2 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEP11981.1 - 0.18 11.3 20.8 0.22 11.0 0.0 3.8 4 0 0 4 4 3 0 zinc-ribbon domain Acetone_carb_G PF08882.11 CEP11981.1 - 0.23 11.6 1.8 5.1 7.3 0.4 2.2 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit Rpr2 PF04032.16 CEP11981.1 - 0.4 11.0 11.7 10 6.5 10.3 2.8 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NOB1_Zn_bind PF08772.11 CEP11981.1 - 0.64 10.2 11.9 4 7.7 0.0 3.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like ArfGap PF01412.18 CEP11981.1 - 0.74 9.9 8.4 0.54 10.3 5.9 1.8 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Terminase_GpA PF05876.12 CEP11981.1 - 0.93 8.0 6.7 0.1 11.2 3.0 1.4 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) HscB_4_cys PF18256.1 CEP11981.1 - 1.4 8.8 10.5 2.6 7.9 3.5 3.7 3 1 1 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif Prok-RING_1 PF14446.6 CEP11981.1 - 1.6 8.7 12.2 0.79 9.7 3.2 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PADR1 PF08063.12 CEP11981.1 - 1.7 8.5 11.6 5.7 6.8 0.1 3.7 4 0 0 4 4 4 0 PADR1 (NUC008) domain zf-ZPR1 PF03367.13 CEP11981.1 - 4.2 7.2 10.7 0.27 11.1 1.3 2.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Nudix_N_2 PF14803.6 CEP11981.1 - 4.5 7.3 15.6 29 4.7 2.5 3.7 2 2 2 4 4 4 0 Nudix N-terminal RecR PF02132.15 CEP11981.1 - 4.8 6.8 11.1 0.26 10.9 1.5 3.1 3 0 0 3 3 3 0 RecR protein zinc_ribbon_9 PF14369.6 CEP11981.1 - 5.7 7.3 12.6 29 5.0 0.4 3.5 3 1 1 4 4 3 0 zinc-ribbon zinc_ribbon_15 PF17032.5 CEP11981.1 - 6.9 7.5 15.2 71 4.3 0.1 3.6 2 1 0 2 2 2 0 zinc-ribbon family OrfB_Zn_ribbon PF07282.11 CEP11981.1 - 9.5 6.2 10.9 4.6 7.2 3.6 2.7 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Dynamitin PF04912.14 CEP11982.1 - 1.6e-87 294.4 28.3 1.8e-87 294.2 28.3 1.0 1 0 0 1 1 1 1 Dynamitin DUF1451 PF07295.11 CEP11982.1 - 0.032 14.3 1.0 0.032 14.3 1.0 2.7 3 0 0 3 3 3 0 Zinc-ribbon containing domain TcpS PF17456.2 CEP11982.1 - 0.75 9.8 7.2 0.18 11.9 2.2 2.6 2 1 0 2 2 2 0 Toxin-coregulated pilus protein S IL11 PF07400.11 CEP11982.1 - 0.84 9.3 5.9 0.22 11.2 0.4 2.7 3 0 0 3 3 3 0 Interleukin 11 Spectrin PF00435.21 CEP11982.1 - 4.2 7.9 15.7 7.5 7.1 0.3 5.0 2 2 2 4 4 4 0 Spectrin repeat Herpes_Helicase PF02689.14 CEP11983.1 - 0.0061 14.6 0.1 0.0065 14.5 0.1 1.0 1 0 0 1 1 1 1 Helicase Amidohydro_1 PF01979.20 CEP11985.1 - 2e-18 66.9 0.7 5.1e-16 58.9 0.2 3.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CEP11985.1 - 4.5e-17 62.7 3.4 1.7e-11 44.3 0.0 3.4 4 0 0 4 4 4 2 Amidohydrolase family DUF3455 PF11937.8 CEP11987.1 - 1.5e-07 31.9 0.1 1.5e-07 31.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) EF-hand_1 PF00036.32 CEP11988.1 - 1.4e-35 118.1 14.6 1.6e-09 36.6 1.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP11988.1 - 1.6e-31 108.5 4.0 2.6e-17 63.0 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP11988.1 - 3.8e-27 91.9 7.7 1.9e-07 30.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEP11988.1 - 6e-27 91.9 13.5 2.6e-07 29.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CEP11988.1 - 2.5e-26 91.3 13.1 5.5e-12 45.3 1.9 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CEP11988.1 - 1.4e-12 47.7 0.0 7.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CEP11988.1 - 2.8e-08 33.6 2.7 0.0044 17.0 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEP11988.1 - 3.5e-08 33.8 0.3 3.7e-05 24.0 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 CEP11988.1 - 0.0031 17.5 0.7 0.24 11.4 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 CEP11988.1 - 0.029 14.5 11.1 0.076 13.2 1.7 3.4 1 1 2 3 3 3 0 Dockerin type I domain EF-hand_11 PF08976.11 CEP11988.1 - 0.03 15.2 0.1 0.15 12.9 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 CEP11988.1 - 0.12 12.8 0.1 0.59 10.5 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain UPF0154 PF03672.13 CEP11988.1 - 0.15 12.1 0.0 8.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SurA_N_2 PF13623.6 CEP11988.1 - 0.25 11.2 3.3 0.76 9.6 1.4 2.2 1 1 1 2 2 2 0 SurA N-terminal domain RHH_6 PF16762.5 CEP11988.1 - 0.34 11.5 2.1 4.5 8.0 0.4 2.5 2 1 0 2 2 2 0 Ribbon-helix-helix domain Phos_pyr_kin PF08543.12 CEP11989.1 - 4.1e-85 285.1 1.5 5.5e-85 284.7 1.5 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CEP11989.1 - 2.2e-36 125.6 0.1 2.6e-35 122.2 0.1 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CEP11989.1 - 1e-06 28.3 0.1 2.2e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 CEP11989.1 - 0.0036 16.8 0.1 0.0064 16.0 0.1 1.5 1 1 0 1 1 1 1 Carbohydrate kinase SMC_N PF02463.19 CEP11990.1 - 1e-27 97.0 0.0 2.3e-27 95.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEP11990.1 - 2.4e-17 64.1 7.3 2.4e-17 64.1 7.3 6.4 3 2 2 5 5 5 1 AAA domain AAA_21 PF13304.6 CEP11990.1 - 2e-07 31.2 9.6 0.00056 19.8 0.2 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEP11990.1 - 3.8e-07 30.1 23.3 3.8e-07 30.1 23.3 4.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CEP11990.1 - 1.4e-06 27.9 0.2 4.1e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CEP11990.1 - 0.0061 16.8 0.0 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CEP11990.1 - 0.039 14.4 1.2 0.31 11.4 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 CEP11990.1 - 0.087 13.3 0.1 0.087 13.3 0.1 5.4 4 2 1 5 5 5 0 ABC transporter RsgA_GTPase PF03193.16 CEP11990.1 - 0.21 11.5 1.9 1.2 9.0 0.0 3.3 2 0 0 2 2 2 0 RsgA GTPase GPI-anchored PF10342.9 CEP11991.1 - 1.8e-11 44.6 0.1 1.8e-11 44.6 0.1 1.8 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1180 PF06679.12 CEP11991.1 - 8.8 6.7 10.1 20 5.6 10.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glycos_transf_1 PF00534.20 CEP11992.1 - 1.8e-29 102.5 0.0 5.7e-28 97.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEP11992.1 - 4.3e-15 56.1 0.0 6.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CEP11992.1 - 9.7e-12 45.5 0.0 2.7e-11 44.0 0.0 1.7 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEP11992.1 - 5.7e-06 26.9 0.0 8.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CEP11992.1 - 3.5e-05 24.1 0.0 8.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 CEP11992.1 - 0.063 13.3 0.5 5.8 6.9 0.4 3.0 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus DNA_pol_B PF00136.21 CEP11993.1 - 6.2e-124 414.2 0.1 6.2e-124 414.2 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CEP11993.1 - 6.3e-53 179.3 8.9 1.4e-52 178.2 8.9 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CEP11993.1 - 1.7e-45 155.6 0.0 3.3e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CEP11993.1 - 2.7e-06 27.3 9.1 2.7e-06 27.3 9.1 3.1 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 CEP11993.1 - 0.0021 16.7 0.2 0.0044 15.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.9 CEP11993.1 - 0.015 15.0 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB SPT6_acidic PF14632.6 CEP11993.1 - 0.78 10.4 14.9 3.2 8.4 14.9 2.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DegS PF05384.11 CEP11994.1 - 0.054 13.0 0.2 0.087 12.3 0.2 1.2 1 0 0 1 1 1 0 Sensor protein DegS Usp PF00582.26 CEP11995.1 - 1e-17 64.9 0.0 2.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family DUF4729 PF15866.5 CEP11995.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4729) Ribosomal_S26e PF01283.19 CEP11997.1 - 1.4e-53 179.9 7.5 1.8e-53 179.5 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e DUF4885 PF16226.5 CEP11998.1 - 0.029 13.4 0.1 0.055 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4885) DELLA PF12041.8 CEP11998.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal cNMP_binding PF00027.29 CEP11999.1 - 2.7e-39 133.1 0.4 2.9e-19 68.9 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CEP11999.1 - 8.6e-12 44.5 1.4 1.8e-11 43.5 1.4 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PTPRCAP PF15713.5 CEP11999.1 - 0.042 14.1 1.2 0.082 13.2 1.2 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Septin PF00735.18 CEP12000.1 - 4.4e-112 374.0 1.3 6.4e-112 373.4 1.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP12000.1 - 6.9e-09 35.8 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP12000.1 - 1.3e-06 28.5 0.2 1.3e-06 28.5 0.2 2.7 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CEP12000.1 - 2e-06 27.5 7.6 5.9e-06 26.0 0.1 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CEP12000.1 - 1.1e-05 25.6 0.1 3.2e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CEP12000.1 - 0.00062 20.0 0.2 0.0019 18.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 CEP12000.1 - 0.0012 18.5 0.1 0.0032 17.1 0.1 1.8 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 CEP12000.1 - 0.002 17.5 0.2 0.0054 16.1 0.2 1.7 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CEP12000.1 - 0.004 17.6 0.3 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEP12000.1 - 0.0048 16.3 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 CEP12000.1 - 0.0048 16.0 0.1 0.012 14.6 0.1 1.7 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 CEP12000.1 - 0.0052 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CEP12000.1 - 0.0057 17.0 0.0 0.022 15.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CEP12000.1 - 0.01 15.6 0.4 0.026 14.2 0.4 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CEP12000.1 - 0.011 15.8 8.6 1 9.4 0.1 3.3 2 1 1 3 3 3 0 Dynamin family AAA_7 PF12775.7 CEP12000.1 - 0.012 15.1 0.2 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CEP12000.1 - 0.017 15.1 1.1 0.66 9.9 0.3 2.5 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.12 CEP12000.1 - 0.02 14.4 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.6 CEP12000.1 - 0.026 14.7 1.6 0.085 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CEP12000.1 - 0.034 13.9 0.5 2.5 7.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SecB PF02556.14 CEP12000.1 - 0.039 13.8 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit SecB AAA_23 PF13476.6 CEP12000.1 - 0.052 14.0 16.1 0.12 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEP12000.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CEP12000.1 - 0.065 13.0 1.4 1.4 8.6 0.1 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 CEP12000.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 CEP12000.1 - 0.082 13.5 3.7 0.13 12.9 1.6 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain ABC_tran PF00005.27 CEP12000.1 - 0.084 13.4 0.0 0.084 13.4 0.0 2.1 2 1 0 2 2 1 0 ABC transporter PRK PF00485.18 CEP12000.1 - 0.24 11.1 0.1 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ALMT PF11744.8 CEP12000.1 - 0.25 10.1 3.2 0.39 9.5 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 CEP12000.1 - 0.43 10.1 4.4 0.66 9.5 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 CEP12000.1 - 0.59 10.6 8.3 0.32 11.5 5.2 2.1 2 0 0 2 2 1 0 Protein of unknown function DUF16 ArsA_ATPase PF02374.15 CEP12000.1 - 1.2 8.3 5.4 9.2 5.3 0.6 2.8 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_18 PF13238.6 CEP12000.1 - 1.9 9.1 5.5 0.46 11.0 0.1 2.6 3 2 0 3 3 2 0 AAA domain APG6_N PF17675.1 CEP12000.1 - 2.9 8.4 18.1 1 9.9 14.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 CEP12000.1 - 3.2 7.9 7.3 2.4 8.3 3.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family YojJ PF10372.9 CEP12000.1 - 6.1 7.0 6.2 0.93 9.6 1.6 2.0 3 0 0 3 3 1 0 Bacterial membrane-spanning protein N-terminus PH PF00169.29 CEP12003.1 - 5.1e-44 149.1 6.7 1.9e-22 79.7 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CEP12003.1 - 9.5e-15 54.9 15.1 3.5e-06 27.4 0.6 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 CEP12003.1 - 4.6e-13 49.2 8.1 4.6e-06 26.7 3.8 2.2 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 CEP12003.1 - 6.5e-13 48.8 6.2 3.4e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CEP12003.1 - 2.5e-08 34.3 9.9 0.0099 16.2 6.2 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain Myosin_TH1 PF06017.13 CEP12003.1 - 0.00068 19.4 0.7 0.93 9.1 0.3 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding PH_13 PF16652.5 CEP12003.1 - 0.002 18.0 2.8 0.14 11.9 1.5 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_15 PF17339.2 CEP12003.1 - 0.024 14.5 5.1 0.73 9.8 2.4 2.4 2 0 0 2 2 2 0 PH domain BCL_N PF04714.13 CEP12003.1 - 0.38 10.8 5.1 0.96 9.6 1.5 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region OHCU_decarbox PF09349.10 CEP12004.1 - 0.13 12.8 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 OHCU decarboxylase KDZ PF18758.1 CEP12006.1 - 9.4e-27 94.1 1.0 2.5e-26 92.7 1.0 1.7 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP12006.1 - 0.0059 16.7 0.1 0.018 15.2 0.1 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Bax1-I PF01027.20 CEP12007.1 - 3.9e-51 173.8 31.4 4.6e-51 173.6 31.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Acyl-CoA_dh_1 PF00441.24 CEP12008.1 - 3.9e-31 108.3 0.1 9.9e-31 107.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CEP12008.1 - 7.5e-21 74.1 0.0 1.9e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CEP12008.1 - 8.8e-17 61.1 0.1 1.5e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEP12008.1 - 7.4e-12 45.9 0.0 3.1e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP12008.1 - 0.00071 19.9 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 CEP12009.1 - 1.7e-73 247.3 0.0 2.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12009.1 - 2.2e-36 125.5 0.0 2.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CEP12009.1 - 1.5e-15 57.3 0.0 3.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 CEP12009.1 - 4e-05 23.1 0.1 7.6e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP12009.1 - 0.00017 20.6 0.2 0.00026 20.1 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP12009.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 CEP12009.1 - 0.0043 17.3 0.0 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pox_ser-thr_kin PF05445.11 CEP12009.1 - 0.0075 15.3 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CEP12009.1 - 0.031 14.2 0.3 2.4 8.0 0.0 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family FMO-like PF00743.19 CEP12010.1 - 4.4e-48 164.0 0.0 1.3e-33 116.2 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CEP12010.1 - 6.2e-20 71.7 0.0 8.2e-14 51.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEP12010.1 - 2.7e-15 56.4 0.0 8e-15 54.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEP12010.1 - 9e-11 41.5 0.0 6.5e-08 32.1 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CEP12010.1 - 1.7e-08 34.6 0.6 0.0024 17.9 0.0 3.5 4 0 0 4 4 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CEP12010.1 - 4.5e-08 33.2 0.0 2.3e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP12010.1 - 7.4e-07 29.1 0.2 0.0022 17.7 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CEP12010.1 - 7.6e-05 23.2 0.3 0.1 13.2 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP12010.1 - 0.00036 20.0 0.0 0.00066 19.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEP12010.1 - 0.0068 15.7 0.5 0.029 13.6 0.0 2.2 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 CEP12010.1 - 0.015 14.0 0.0 0.09 11.5 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 CEP12010.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 CEP12010.1 - 0.051 12.8 0.2 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 CEP12010.1 - 0.07 12.7 0.1 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 CEP12010.1 - 0.1 11.7 0.1 1.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Semialdhyde_dh PF01118.24 CEP12010.1 - 0.11 12.9 0.0 12 6.4 0.0 2.9 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CEP12010.1 - 0.21 11.6 1.2 14 5.7 0.0 3.1 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CEP12010.1 - 0.21 12.0 3.6 12 6.4 0.8 3.1 2 2 0 2 2 2 0 Putative NAD(P)-binding Thioredoxin PF00085.20 CEP12011.1 - 1.6e-33 114.7 0.0 1.5e-24 85.9 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CEP12011.1 - 3.6e-10 40.0 0.1 1.2e-06 28.6 0.1 3.3 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CEP12011.1 - 9.7e-08 32.4 0.4 0.001 19.5 0.1 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP12011.1 - 7.4e-07 29.4 2.7 0.066 13.6 0.3 5.0 2 2 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CEP12011.1 - 0.00016 21.1 0.6 0.019 14.3 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family QSOX_Trx1 PF18108.1 CEP12011.1 - 0.087 13.0 0.0 0.85 9.8 0.0 2.3 2 0 0 2 2 2 0 QSOX Trx-like domain Retrotrans_gag PF03732.17 CEP12012.1 - 0.061 13.6 0.0 0.061 13.6 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon gag protein Ribosomal_S5_C PF03719.15 CEP12012.1 - 0.063 12.7 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain AAA_17 PF13207.6 CEP12013.1 - 0.13 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain HSCB_C PF07743.13 CEP12013.1 - 0.95 10.0 10.8 0.19 12.2 1.3 3.3 2 2 2 4 4 4 0 HSCB C-terminal oligomerisation domain RT_RNaseH PF17917.1 CEP12014.1 - 1.5e-32 112.0 0.0 3.1e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP12014.1 - 3e-26 91.4 0.0 5.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP12014.1 - 8.8e-17 61.4 0.0 1.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KDZ PF18758.1 CEP12015.1 - 1.7e-26 93.2 0.3 3.5e-19 69.3 0.1 2.5 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CEP12015.1 - 0.005 17.0 0.7 0.015 15.5 0.7 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 CEP12015.1 - 0.04 14.1 0.7 0.12 12.6 0.4 1.9 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases MDD_C PF18376.1 CEP12016.1 - 8.3e-74 247.4 0.0 1.3e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CEP12016.1 - 1.2e-07 31.8 1.9 2.3e-07 31.0 1.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain tRNA-synt_1c PF00749.21 CEP12017.1 - 8.4e-106 353.4 0.0 8.4e-106 353.4 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain RMI1_N PF08585.12 CEP12017.1 - 1.4e-12 47.8 0.1 1.4e-12 47.8 0.1 5.1 3 2 1 4 4 4 2 RecQ mediated genome instability protein Ribosomal_L7Ae PF01248.26 CEP12018.1 - 2.9e-26 91.1 0.0 3.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-RanBP PF00641.18 CEP12019.1 - 4.6e-35 118.6 49.4 9.4e-09 34.4 3.5 5.3 5 0 0 5 5 5 5 Zn-finger in Ran binding protein and others RNase_T PF00929.24 CEP12019.1 - 2.3e-08 34.8 0.9 3.3e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.22 CEP12019.1 - 6.9e-08 32.2 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 CEP12020.1 - 1.2e-16 61.7 0.7 2.7e-08 34.5 0.3 2.5 1 1 1 2 2 2 2 Exonuclease Sugar_tr PF00083.24 CEP12021.1 - 3.1e-104 349.4 19.3 3.6e-104 349.1 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP12021.1 - 1.1e-25 90.3 34.7 5e-17 61.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CEP12021.1 - 6.6e-05 21.5 1.2 6.6e-05 21.5 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CEP12021.1 - 2.8 6.1 7.8 6.5 4.9 0.7 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HNH PF01844.23 CEP12022.1 - 0.026 14.7 0.9 0.05 13.8 0.9 1.5 1 0 0 1 1 1 0 HNH endonuclease Cu-oxidase_2 PF07731.14 CEP12022.1 - 0.068 12.9 0.3 8.1 6.2 0.4 2.2 2 0 0 2 2 2 0 Multicopper oxidase 6PF2K PF01591.18 CEP12023.1 - 1.6e-71 240.2 0.1 2.4e-71 239.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP12023.1 - 9e-33 113.6 0.0 1.4e-23 83.6 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEP12023.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEP12023.1 - 0.00031 20.3 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CEP12023.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CEP12023.1 - 0.036 14.5 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NRDE-2 PF08424.10 CEP12023.1 - 0.039 13.1 0.2 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Peptidase_C58 PF03543.14 CEP12023.1 - 0.11 12.2 0.1 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Ank_2 PF12796.7 CEP12024.1 - 0.0029 18.2 0.3 0.015 15.8 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PDDEXK_6 PF04720.12 CEP12024.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Ank PF00023.30 CEP12024.1 - 0.017 15.5 0.1 0.069 13.6 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 CEP12024.1 - 0.03 14.9 0.1 0.31 11.7 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP12024.1 - 0.037 14.6 0.1 0.2 12.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF2789 PF10982.8 CEP12024.1 - 0.19 11.9 1.0 0.46 10.7 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2789) GAF_2 PF13185.6 CEP12025.1 - 2.4e-08 34.3 0.0 5.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CEP12025.1 - 6.7e-06 26.8 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain PDZ_5 PF17817.1 CEP12025.1 - 0.15 12.4 2.3 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 PDZ domain SH3_9 PF14604.6 CEP12026.1 - 9.7e-08 31.8 0.1 3.4e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CEP12026.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP12026.1 - 6e-05 22.6 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain CYYR1 PF10873.8 CEP12026.1 - 0.00078 19.9 3.0 0.0017 18.8 3.0 1.5 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 FAM163 PF15069.6 CEP12026.1 - 0.0039 17.6 2.3 0.0064 17.0 0.0 2.4 4 0 0 4 4 4 1 FAM163 family Syndecan PF01034.20 CEP12026.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain CPG4 PF15481.6 CEP12026.1 - 0.87 10.3 6.7 16 6.2 0.1 2.9 3 0 0 3 3 3 0 Chondroitin proteoglycan 4 Ribosomal_S21e PF01249.18 CEP12027.1 - 5.8e-40 135.3 0.0 6.4e-40 135.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1682 PF07946.14 CEP12028.1 - 1.8e-85 287.0 1.2 2.1e-85 286.8 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SRI PF08236.11 CEP12028.1 - 1.4 9.2 10.5 0.79 9.9 7.9 2.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain CBP4 PF07960.11 CEP12029.1 - 5.7e-16 58.6 0.1 6.3e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 CEP12029.1 - 0.00013 21.8 0.3 0.00015 21.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 TMEM40 PF15817.5 CEP12030.1 - 0.24 11.2 2.6 0.71 9.6 2.6 1.9 1 0 0 1 1 1 0 Transmembrane protein 40 family Homeodomain PF00046.29 CEP12031.1 - 4.6e-16 58.4 2.4 1.2e-15 57.1 2.4 1.8 1 0 0 1 1 1 1 Homeodomain F_actin_cap_B PF01115.17 CEP12032.1 - 7.8e-105 349.8 0.0 1.1e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Lectin_leg-like PF03388.13 CEP12032.1 - 1.5e-69 233.8 0.0 2.2e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CEP12032.1 - 3.2e-07 30.5 0.2 5.8e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CEP12032.1 - 2.1e-06 27.4 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain F-actin_cap_A PF01267.17 CEP12032.1 - 0.00011 21.8 0.0 0.0012 18.3 0.0 2.3 1 1 1 2 2 2 1 F-actin capping protein alpha subunit Sbi-IV PF11621.8 CEP12033.1 - 0.0028 18.0 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 C3 binding domain 4 of IgG-bind protein SBI HAMP PF00672.25 CEP12034.1 - 4.4e-25 87.8 4.0 1.8e-09 37.8 0.1 3.9 3 2 0 3 3 3 3 HAMP domain DUF948 PF06103.11 CEP12034.1 - 0.0022 18.2 23.3 2.7 8.3 1.4 4.8 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF948) PseudoU_synth_1 PF01416.20 CEP12034.1 - 0.0032 17.9 0.6 20 5.7 0.0 3.2 2 1 1 3 3 3 0 tRNA pseudouridine synthase ImcF-related_N PF14331.6 CEP12034.1 - 0.0089 15.4 0.0 0.9 8.8 0.0 2.1 2 0 0 2 2 2 1 ImcF-related N-terminal domain WXG100 PF06013.12 CEP12034.1 - 0.0095 16.2 4.0 0.36 11.1 0.1 3.4 2 1 2 4 4 4 1 Proteins of 100 residues with WXG HTH_6 PF01418.17 CEP12034.1 - 0.011 15.7 0.5 1.2 9.2 0.0 3.3 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family Perilipin PF03036.16 CEP12034.1 - 0.031 13.3 4.8 0.25 10.3 0.1 2.5 3 0 0 3 3 3 0 Perilipin family SpoIIID PF12116.8 CEP12034.1 - 0.046 13.8 3.1 21 5.3 0.1 3.6 3 1 1 4 4 4 0 Stage III sporulation protein D Vac_Fusion PF02346.16 CEP12034.1 - 0.12 12.0 1.2 1e+02 2.6 0.0 4.4 5 1 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 NusG PF02357.19 CEP12034.1 - 0.18 12.4 0.3 95 3.6 0.0 3.1 3 0 0 3 3 3 0 Transcription termination factor nusG DASH_Dad2 PF08654.10 CEP12034.1 - 0.26 11.7 11.5 7.6 7.0 0.3 4.2 2 1 0 3 3 3 0 DASH complex subunit Dad2 DUF1725 PF08333.11 CEP12034.1 - 0.38 10.5 1.4 4 7.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) HAMP PF00672.25 CEP12037.1 - 5.3e-24 84.3 4.7 1.5e-08 34.9 0.1 4.1 4 1 1 5 5 4 3 HAMP domain Baculo_PEP_C PF04513.12 CEP12037.1 - 7.8e-06 26.0 6.7 0.051 13.6 0.2 3.3 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 CEP12037.1 - 0.00037 19.7 0.0 0.83 8.7 0.0 2.7 1 1 2 3 3 3 2 Autophagy protein Apg17 DUF948 PF06103.11 CEP12037.1 - 0.007 16.6 15.1 0.44 10.8 2.5 4.2 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) HTH_6 PF01418.17 CEP12037.1 - 0.016 15.2 2.6 26 4.9 0.0 4.0 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family Ubiquitin_4 PF18036.1 CEP12037.1 - 0.018 15.1 2.1 20 5.3 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-like domain GIT_CC PF16559.5 CEP12037.1 - 0.023 14.5 0.1 44 4.0 0.0 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3829 PF12889.7 CEP12037.1 - 0.024 14.1 0.2 4.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF4731 PF15875.5 CEP12037.1 - 0.031 14.5 0.6 1.9 8.8 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4731) SpoIIID PF12116.8 CEP12037.1 - 0.032 14.3 0.3 2 8.6 0.1 2.6 2 0 0 2 2 2 0 Stage III sporulation protein D Syntaxin_2 PF14523.6 CEP12037.1 - 0.032 14.6 0.0 2.4 8.6 0.0 2.5 1 1 0 2 2 2 0 Syntaxin-like protein DUF1843 PF08898.10 CEP12037.1 - 0.035 14.6 0.3 4.8 7.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Zw10 PF06248.13 CEP12037.1 - 0.039 12.5 1.4 0.2 10.2 1.7 2.0 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 DUF2779 PF11074.8 CEP12037.1 - 0.045 14.2 0.0 60 4.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function(DUF2779) Prominin PF05478.11 CEP12037.1 - 0.064 11.2 1.1 0.33 8.9 0.4 2.1 1 1 2 3 3 3 0 Prominin Vps52 PF04129.12 CEP12037.1 - 0.067 11.9 0.2 18 3.9 0.0 3.0 3 0 0 3 3 3 0 Vps52 / Sac2 family Rab5-bind PF09311.11 CEP12037.1 - 0.07 12.5 2.0 3.4 7.0 0.2 2.3 1 1 1 2 2 2 0 Rabaptin-like protein DUF1759 PF03564.15 CEP12037.1 - 0.086 12.8 1.5 15 5.5 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1759) ArnB_C PF18677.1 CEP12037.1 - 0.1 12.7 3.9 1.1 9.4 0.1 3.5 3 2 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain DASH_Dad2 PF08654.10 CEP12037.1 - 0.13 12.7 7.4 6.8 7.2 1.0 3.9 2 1 1 3 3 3 0 DASH complex subunit Dad2 OspD PF03207.13 CEP12037.1 - 0.16 11.3 8.9 1.3 8.3 0.3 3.3 1 1 2 4 4 4 0 Borrelia outer surface protein D (OspD) DUF3852 PF12963.7 CEP12037.1 - 0.17 12.3 4.0 13 6.2 0.2 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF3852) Vac_Fusion PF02346.16 CEP12037.1 - 0.35 10.5 2.5 1.4e+02 2.2 0.0 4.7 6 1 0 6 6 6 0 Chordopoxvirus multifunctional envelope protein A27 RT_RNaseH_2 PF17919.1 CEP12038.1 - 0.0026 17.7 0.0 0.0082 16.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP12038.1 - 0.01 16.0 0.0 4.6 7.4 0.1 2.4 1 1 1 2 2 2 0 Integrase core domain EIID-AGA PF03613.14 CEP12039.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Serine_protease PF18405.1 CEP12039.1 - 0.15 11.2 0.3 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease COX7C PF02935.16 CEP12041.1 - 1.1e-11 44.8 0.1 3.5e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc EphA2_TM PF14575.6 CEP12041.1 - 0.0083 17.0 0.0 0.03 15.2 0.0 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 CEP12041.1 - 0.0089 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Cadherin_C_2 PF16492.5 CEP12041.1 - 0.02 15.6 0.0 0.063 14.0 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 CEP12041.1 - 0.024 14.5 2.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Stevor PF17410.2 CEP12041.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Syndecan PF01034.20 CEP12041.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Hum_adeno_E3A PF05393.11 CEP12041.1 - 0.11 12.4 1.1 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Polysacc_deac_1 PF01522.21 CEP12042.1 - 2.2e-26 92.2 0.1 3.9e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Ank_2 PF12796.7 CEP12043.1 - 1.3e-43 147.5 4.2 8.7e-20 71.1 0.3 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP12043.1 - 1.2e-39 134.2 6.9 2.6e-14 53.4 0.1 5.6 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 CEP12043.1 - 1.1e-28 98.4 8.0 0.00044 20.6 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 CEP12043.1 - 9.4e-27 90.1 8.9 0.0073 16.7 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 CEP12043.1 - 5.3e-26 90.3 11.1 7e-08 32.6 0.1 6.6 3 1 3 6 6 6 6 Ankyrin repeats (many copies) GDPD PF03009.17 CEP12043.1 - 1.7e-23 83.7 0.0 8.1e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 CEP12043.1 - 8e-23 82.0 21.5 7.3e-10 39.3 3.2 3.7 2 1 2 4 4 4 3 SPX domain SSP160 PF06933.11 CEP12043.1 - 0.72 8.0 15.5 1.1 7.4 15.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 CEP12043.1 - 3.6 5.6 6.3 5.3 5.0 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L11 PF00298.19 CEP12044.1 - 0.88 10.1 4.1 0.97 10.0 0.6 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Ribosomal_L14 PF00238.19 CEP12045.1 - 3.1e-36 124.1 0.2 3.7e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e AA_permease PF00324.21 CEP12046.1 - 2e-137 458.7 42.6 2.5e-137 458.4 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP12046.1 - 3e-43 148.2 44.1 3.7e-43 147.9 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 CEP12046.1 - 0.18 10.5 17.4 0.56 8.9 0.0 3.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) TPR_1 PF00515.28 CEP12047.1 - 1.1e-42 142.2 38.3 2.6e-05 23.8 0.7 16.0 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12047.1 - 6.5e-41 135.2 25.8 1.7e-05 24.5 1.2 15.8 15 0 0 15 15 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 CEP12047.1 - 1e-36 125.2 20.2 5.1e-08 33.3 0.1 10.3 8 3 3 11 11 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 CEP12047.1 - 5.9e-33 113.0 32.4 2.9e-09 37.1 0.1 10.9 9 3 4 13 13 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 CEP12047.1 - 3.2e-32 108.4 6.8 2.3e-05 24.8 0.0 14.8 8 4 8 16 16 16 6 Tetratricopeptide repeat TPR_8 PF13181.6 CEP12047.1 - 6.3e-30 100.9 36.7 0.00013 21.9 0.2 15.2 17 1 0 17 17 17 7 Tetratricopeptide repeat TPR_16 PF13432.6 CEP12047.1 - 5.6e-29 100.5 5.4 2.7e-05 24.7 0.1 9.4 8 1 2 10 10 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 CEP12047.1 - 4.7e-26 88.9 19.7 0.0032 17.4 0.0 12.7 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 CEP12047.1 - 2.5e-25 87.4 27.3 8.9e-05 22.9 0.1 14.0 13 1 1 14 14 13 6 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12047.1 - 1.9e-17 62.3 23.2 5.5e-05 23.3 0.2 12.8 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP12047.1 - 4.3e-14 51.9 21.2 0.013 15.2 0.0 11.3 7 4 5 12 12 12 5 TPR repeat ANAPC3 PF12895.7 CEP12047.1 - 3.6e-12 46.4 22.9 9.3e-05 22.6 1.1 5.8 6 1 1 7 7 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEP12047.1 - 3.7e-10 39.8 2.3 0.33 11.1 0.0 8.2 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP12047.1 - 2.3e-09 36.8 24.1 0.056 13.3 0.1 10.5 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEP12047.1 - 1e-08 34.8 26.4 0.00014 21.2 1.2 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.10 CEP12047.1 - 0.00018 20.6 0.7 0.00018 20.6 0.7 2.8 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 CEP12047.1 - 0.00033 19.5 8.8 0.37 9.5 0.4 4.1 5 0 0 5 5 5 3 Protein kinase G tetratricopeptide repeat TPPII_N PF12583.8 CEP12047.1 - 0.0027 18.3 4.5 0.49 11.0 0.0 3.9 3 1 1 4 4 3 1 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 CEP12047.1 - 0.1 12.7 0.1 0.1 12.7 0.1 7.2 9 0 0 9 9 7 0 Fis1 C-terminal tetratricopeptide repeat RPN2_C PF18004.1 CEP12048.1 - 1.2e-54 184.6 7.8 1.2e-54 184.6 7.8 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CEP12048.1 - 7.7e-43 142.8 24.4 1.9e-08 34.3 0.1 9.1 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CEP12048.1 - 2.1e-19 69.7 0.2 1.9e-12 47.4 0.0 5.1 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.22 CEP12048.1 - 7.2e-07 28.9 0.2 6.7 7.3 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 CEP12048.1 - 0.0049 17.3 1.3 0.97 10.0 0.0 4.3 4 1 0 4 4 4 1 HEAT-like repeat Importin_rep_6 PF18829.1 CEP12048.1 - 0.035 14.2 1.9 1.1 9.4 0.7 2.9 2 0 0 2 2 2 0 Importin repeat 6 HEAT_PBS PF03130.16 CEP12048.1 - 0.078 13.7 1.2 1.6e+02 3.4 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Methyltransf_16 PF10294.9 CEP12050.1 - 4.1e-28 98.3 0.1 1.1e-26 93.6 0.1 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CEP12050.1 - 0.00011 22.0 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain LRRC37 PF15779.5 CEP12050.1 - 0.17 12.2 2.6 0.23 11.8 0.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeat-containing protein 37 family Stk19 PF10494.9 CEP12052.1 - 3.1e-23 82.7 0.0 4.2e-17 62.7 0.0 2.1 1 1 1 2 2 2 2 Serine-threonine protein kinase 19 DDE_3 PF13358.6 CEP12053.1 - 2.6e-26 92.2 0.0 1.2e-17 64.0 0.0 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP12053.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 CEP12053.1 - 0.1 12.8 0.1 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CEP12053.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MIF4G PF02854.19 CEP12054.1 - 1.2e-62 211.3 10.9 8e-35 120.4 0.2 4.1 4 1 1 5 5 5 3 MIF4G domain Upf2 PF04050.14 CEP12054.1 - 1.2e-38 132.9 11.0 1.2e-38 132.9 11.0 2.9 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Lysine_decarbox PF03641.14 CEP12054.1 - 2.8e-37 127.8 0.0 7.2e-37 126.4 0.0 1.8 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CEP12054.1 - 6.8e-19 68.0 0.0 1.7e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 SLOG cluster4 family Ras PF00071.22 CEP12055.1 - 2.8e-56 189.6 0.3 3.6e-56 189.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP12055.1 - 1.1e-30 106.4 0.2 2.5e-30 105.1 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP12055.1 - 7.9e-10 38.5 0.1 1.1e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP12055.1 - 6.1e-05 22.7 0.2 0.00014 21.4 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP12055.1 - 0.012 15.5 1.5 0.37 10.7 0.2 2.6 1 1 2 3 3 3 0 RsgA GTPase DUF2726 PF10881.8 CEP12055.1 - 0.051 13.5 0.1 0.091 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) zf-C2H2 PF00096.26 CEP12056.1 - 1.8e-07 31.3 15.2 0.00036 20.8 4.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 CEP12056.1 - 0.0042 17.7 5.4 0.92 10.2 0.8 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CEP12056.1 - 0.022 15.2 4.4 0.022 15.2 4.4 3.8 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEP12056.1 - 0.044 14.1 8.0 0.44 10.9 7.9 2.3 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 CEP12056.1 - 3.1 8.9 22.2 0.27 12.2 3.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger La PF05383.17 CEP12057.1 - 6.8e-08 32.4 0.1 2.7e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 CEP12057.1 - 1.4e-07 31.2 0.0 4.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GP17 PF17420.2 CEP12057.1 - 0.035 14.3 0.3 0.084 13.0 0.3 1.6 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 RRM_7 PF16367.5 CEP12057.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DAO PF01266.24 CEP12058.1 - 1.1e-55 189.6 0.0 1.3e-55 189.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 CEP12058.1 - 0.0081 16.4 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 CEP12058.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP12058.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CEP12058.1 - 0.077 12.2 0.5 0.41 9.9 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CEP12058.1 - 0.1 12.8 0.1 1.5 9.1 0.0 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Mqo PF06039.15 CEP12058.1 - 0.1 11.1 0.0 0.24 9.9 0.1 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 CEP12058.1 - 0.14 12.2 0.3 0.41 10.6 0.3 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.25 CEP12059.1 - 2.6e-54 184.3 0.0 2.3e-28 99.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12059.1 - 4.4e-21 75.3 0.1 1.3e-13 50.9 0.2 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ish1 PF10281.9 CEP12059.1 - 0.021 15.1 0.5 0.11 12.8 0.1 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ank_2 PF12796.7 CEP12060.1 - 1.8e-16 60.5 0.1 2e-09 37.9 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP12060.1 - 4.1e-16 59.1 0.0 2e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP12060.1 - 3.5e-12 46.3 0.0 6.8e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP12060.1 - 8.8e-12 44.1 0.0 1.2e-05 25.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CEP12060.1 - 1.2e-11 44.5 0.0 5.8e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PhaP_Bmeg PF09602.10 CEP12060.1 - 0.046 13.6 5.8 0.077 12.9 5.8 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4404 PF14357.6 CEP12060.1 - 0.14 12.8 5.4 6.7 7.4 3.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) FlxA PF14282.6 CEP12061.1 - 0.018 15.0 7.1 0.018 15.0 7.1 5.9 1 1 5 6 6 6 0 FlxA-like protein DUF2155 PF09923.9 CEP12061.1 - 0.033 14.4 2.1 0.068 13.4 0.6 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF2353 PF09789.9 CEP12061.1 - 1.3 8.3 58.7 0.039 13.3 30.9 3.6 1 1 3 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) RicinB_lectin_2 PF14200.6 CEP12062.1 - 1.3e-16 61.0 0.4 1.5e-09 38.5 0.0 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP12062.1 - 6.7e-13 49.0 8.4 4.2e-07 30.3 1.2 2.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain DUF4653 PF15546.6 CEP12062.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) RVT_1 PF00078.27 CEP12065.1 - 1.5e-34 119.5 0.2 2.6e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Effector_1 PF04518.12 CEP12065.1 - 0.00076 18.7 0.2 0.56 9.3 0.0 2.7 3 0 0 3 3 3 2 Effector from type III secretion system Retrotrans_gag PF03732.17 CEP12065.1 - 0.0014 18.9 0.1 0.0038 17.5 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-LYAR PF08790.11 CEP12065.1 - 0.0022 17.8 0.3 3.1 7.8 0.0 2.6 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger DUF2393 PF09624.10 CEP12065.1 - 0.005 16.8 0.7 0.011 15.8 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2393) DUF1542 PF07564.11 CEP12065.1 - 0.019 15.1 0.1 8.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) MLIP PF15274.6 CEP12065.1 - 0.056 13.3 1.3 7.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Muscular LMNA-interacting protein PHD PF00628.29 CEP12065.1 - 0.062 13.2 0.3 17 5.4 0.0 2.5 2 0 0 2 2 2 0 PHD-finger HTH_51 PF18558.1 CEP12065.1 - 0.11 12.4 0.2 23 5.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2526 PF10735.9 CEP12065.1 - 0.11 12.7 0.0 33 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Mss4 PF04421.13 CEP12065.1 - 0.25 11.5 0.9 28 4.9 0.0 3.0 3 0 0 3 3 2 0 Mss4 protein Retrotran_gag_2 PF14223.6 CEP12065.1 - 2.1 8.0 5.5 0.75 9.5 0.2 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Arrestin_C PF02752.22 CEP12066.1 - 7.4e-05 23.2 0.5 0.00014 22.3 0.5 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP12066.1 - 0.00029 20.9 0.1 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SNF2_N PF00176.23 CEP12067.1 - 5.5e-74 249.0 0.8 1.6e-73 247.5 0.8 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CEP12067.1 - 2.7e-41 140.1 3.0 2.7e-41 140.1 3.0 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 CEP12067.1 - 7.5e-30 103.9 7.0 7.5e-30 103.9 7.0 3.6 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 CEP12067.1 - 3.2e-19 69.3 0.0 1e-18 67.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP12067.1 - 1.6e-11 44.5 0.2 1.5e-10 41.3 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DBINO PF13892.6 CEP12067.1 - 3.2e-05 24.3 0.9 3.2e-05 24.3 0.9 5.1 5 1 1 6 6 4 1 DNA-binding domain Myb_DNA-binding PF00249.31 CEP12067.1 - 0.0001 22.4 0.2 0.9 9.8 0.0 3.4 2 1 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 CEP12067.1 - 0.00013 21.2 0.0 0.00036 19.8 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 CEP12067.1 - 0.00018 21.4 0.1 0.00058 19.7 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DEAD PF00270.29 CEP12067.1 - 0.00043 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CEP12067.1 - 0.0073 15.6 0.0 0.0073 15.6 0.0 2.8 3 1 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 CEP12067.1 - 0.042 13.9 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEP12067.1 - 0.12 12.6 0.9 0.61 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Occludin_ELL PF07303.13 CEP12067.1 - 2 9.2 10.3 0.06 14.1 2.7 2.5 2 0 0 2 2 1 0 Occludin homology domain zf-C2H2 PF00096.26 CEP12068.1 - 1.9e-06 28.0 19.1 0.00027 21.2 5.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP12068.1 - 5.6e-05 23.4 1.1 5.6e-05 23.4 1.1 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.7 CEP12068.1 - 0.0028 18.0 7.4 0.0079 16.5 1.6 3.5 2 1 1 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP12068.1 - 0.0076 17.0 16.6 0.014 16.2 4.7 5.1 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP12068.1 - 0.029 14.6 1.6 0.029 14.6 1.6 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CEP12068.1 - 0.12 12.4 6.2 2.7 8.1 6.1 2.6 1 1 0 1 1 1 0 CpXC protein zf-BED PF02892.15 CEP12068.1 - 0.64 10.1 8.7 16 5.6 1.9 2.8 1 1 1 2 2 2 0 BED zinc finger Spt20 PF12090.8 CEP12068.1 - 2.3 7.8 26.6 3.2 7.3 15.9 2.6 2 0 0 2 2 2 0 Spt20 family zf-C2HC_2 PF13913.6 CEP12068.1 - 2.7 8.0 14.7 0.84 9.6 1.7 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PQ-loop PF04193.14 CEP12069.1 - 2.8e-19 68.7 1.0 2.8e-19 68.7 1.0 2.4 2 0 0 2 2 2 1 PQ loop repeat 3-PAP PF12578.8 CEP12069.1 - 0.26 11.0 1.3 0.38 10.5 1.3 1.2 1 0 0 1 1 1 0 Myotubularin-associated protein Kin17_mid PF10357.9 CEP12071.1 - 2.6e-47 159.8 0.4 2.6e-47 159.8 0.4 3.5 4 1 1 5 5 4 1 Domain of Kin17 curved DNA-binding protein OB_NTP_bind PF07717.16 CEP12071.1 - 6.2e-22 77.8 0.1 2.9e-21 75.6 0.1 2.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CEP12071.1 - 2.9e-18 66.1 0.1 2.9e-18 66.1 0.1 4.5 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP12071.1 - 1.3e-15 57.7 0.0 5.2e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP12071.1 - 1.5e-06 28.1 0.1 5.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP12071.1 - 9.4e-05 22.7 1.8 0.0015 18.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CEP12071.1 - 0.00089 19.0 0.8 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEP12071.1 - 0.0073 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CEP12071.1 - 0.0073 16.6 0.7 0.09 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 CEP12071.1 - 0.032 14.2 0.3 0.12 12.4 0.0 2.2 2 0 0 2 2 1 0 CDC6, C terminal winged helix domain SRP54 PF00448.22 CEP12071.1 - 0.038 13.6 0.1 0.31 10.6 0.1 2.5 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain zf-C2H2_jaz PF12171.8 CEP12071.1 - 0.073 13.4 5.8 0.17 12.2 5.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PWI PF01480.17 CEP12071.1 - 0.079 13.3 0.3 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 PWI domain zf-met PF12874.7 CEP12071.1 - 0.11 12.9 5.3 0.23 11.9 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Mito_carr PF00153.27 CEP12072.1 - 6.9e-73 240.7 2.4 6.9e-26 90.0 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CEP12072.1 - 1.9e-19 69.9 9.5 1.4e-06 28.6 1.2 5.1 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.6 CEP12072.1 - 1.7e-14 52.5 14.0 0.00011 21.8 0.0 7.1 7 0 0 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 CEP12072.1 - 3.8e-14 51.1 14.1 1.3e-05 24.4 0.0 6.2 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 CEP12072.1 - 3.7e-09 36.3 4.7 0.13 12.2 0.4 4.7 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEP12072.1 - 0.0015 17.9 2.3 3 7.5 0.1 4.1 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CEP12072.1 - 0.25 11.7 2.1 11 6.4 0.0 4.1 5 0 0 5 5 5 0 EF-hand domain EF-hand_4 PF12763.7 CEP12072.1 - 0.85 9.6 3.0 1.5 8.8 0.1 2.8 3 1 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CEP12073.1 - 6.8e-72 242.0 0.0 5.4e-71 239.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12073.1 - 5.3e-34 117.7 0.0 6.9e-32 110.7 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP12073.1 - 1.5e-07 31.1 1.1 0.0036 16.7 0.5 2.6 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 CEP12073.1 - 0.00014 21.5 0.8 0.00033 20.3 0.8 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CEP12073.1 - 0.0088 14.9 0.0 0.0088 14.9 0.0 2.1 3 1 0 3 3 3 1 Fungal protein kinase Tim17 PF02466.19 CEP12074.1 - 1.4e-14 54.4 0.5 9.1e-14 51.8 0.4 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 CEP12074.1 - 2.2 8.5 5.6 11 6.2 2.4 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5518) T6SS_VasE PF05936.12 CEP12075.1 - 0.12 11.0 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Myb_DNA-bind_4 PF13837.6 CEP12076.1 - 0.0043 17.4 0.3 0.0071 16.7 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3439 PF11921.8 CEP12076.1 - 3.1 7.8 11.3 5.3 7.0 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SE PF08491.10 CEP12077.1 - 3.3e-108 360.9 0.0 5.3e-108 360.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase SAPS PF04499.15 CEP12077.1 - 7.7e-102 341.6 13.7 7.7e-55 186.6 10.3 3.0 1 1 2 3 3 3 2 SIT4 phosphatase-associated protein FAD_binding_3 PF01494.19 CEP12077.1 - 1.3e-14 54.2 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CEP12077.1 - 1.7e-06 27.9 0.0 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP12077.1 - 0.0016 17.6 0.9 1.1 8.3 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 CEP12077.1 - 0.002 17.3 0.8 0.012 14.7 0.8 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CEP12077.1 - 0.0038 17.4 0.2 0.0085 16.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP12077.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 CEP12077.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.18 CEP12077.1 - 0.12 10.9 0.1 0.22 10.0 0.1 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 CEP12077.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RisS_PPD PF16524.5 CEP12077.1 - 0.16 12.3 0.1 0.44 10.8 0.1 1.7 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Cupin_4 PF08007.12 CEP12078.1 - 0.13 11.8 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Fungal_TACC PF12709.7 CEP12078.1 - 0.13 12.7 3.9 0.4 11.1 3.9 1.8 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Aa_trans PF01490.18 CEP12079.1 - 9.8e-62 209.0 23.2 1.2e-61 208.7 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2427 PF10348.9 CEP12079.1 - 2.5 7.9 6.5 11 5.9 1.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF2427) Saf_2TM PF18303.1 CEP12079.1 - 6.8 6.3 9.3 1.4 8.5 1.4 3.2 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain bZIP_1 PF00170.21 CEP12080.1 - 1.3e-10 41.2 9.0 1.3e-10 41.2 9.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP12080.1 - 1e-06 28.7 7.7 1e-06 28.7 7.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 CEP12080.1 - 1.1e-05 25.8 0.2 1.1e-05 25.8 0.2 3.7 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 CEP12080.1 - 1.8e-05 25.0 2.1 1.8e-05 25.0 2.1 3.2 2 1 1 3 3 3 1 Aft1 HRA domain bZIP_Maf PF03131.17 CEP12080.1 - 0.027 15.0 4.9 0.027 15.0 4.9 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor HALZ PF02183.18 CEP12080.1 - 0.036 14.3 3.5 0.059 13.6 3.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 CEP12080.1 - 1.1 9.1 3.4 3 7.7 3.4 1.7 1 0 0 1 1 1 0 Septum formation initiator Mg_trans_NIPA PF05653.14 CEP12082.1 - 8.3e-17 61.2 21.2 7.7e-12 44.9 8.6 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA Ac76 PF05814.11 CEP12082.1 - 0.0017 18.3 2.4 0.0017 18.3 2.4 2.7 3 0 0 3 3 3 1 Orf76 (Ac76) NST1 PF13945.6 CEP12083.1 - 4.3e-46 157.5 13.3 4.3e-46 157.5 13.3 4.0 2 1 2 4 4 4 1 Salt tolerance down-regulator CUE PF02845.16 CEP12084.1 - 6.7e-10 38.5 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Vma12 PF11712.8 CEP12084.1 - 0.01 15.9 2.1 0.023 14.8 2.1 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PHA_gran_rgn PF09650.10 CEP12084.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) EF_assoc_2 PF08356.12 CEP12085.1 - 4.3e-36 122.8 0.0 1.2e-35 121.4 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 CEP12085.1 - 2.5e-30 105.2 0.0 2e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 CEP12085.1 - 1.4e-28 98.3 3.5 2.8e-28 97.3 3.5 1.5 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 CEP12085.1 - 7.1e-19 68.2 0.0 3.2e-11 43.5 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEP12085.1 - 1.6e-09 37.8 0.2 0.0019 18.3 0.0 3.5 4 1 0 4 4 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CEP12085.1 - 8.5e-08 32.6 0.0 0.0044 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain EF-hand_7 PF13499.6 CEP12085.1 - 3.7e-07 30.5 0.3 0.0016 18.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA PF00004.29 CEP12085.1 - 2.6e-06 27.9 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEP12085.1 - 3.6e-06 27.5 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 CEP12085.1 - 4.2e-06 27.1 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arf PF00025.21 CEP12085.1 - 6e-06 25.8 0.0 0.002 17.6 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 CEP12085.1 - 7.1e-06 26.6 0.0 0.052 14.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter EF-hand_1 PF00036.32 CEP12085.1 - 7.4e-06 25.2 5.5 0.019 14.5 0.5 2.5 2 0 0 2 2 2 2 EF hand NACHT PF05729.12 CEP12085.1 - 9.9e-06 25.6 0.1 0.21 11.5 0.0 3.1 2 1 1 3 3 3 2 NACHT domain AAA_7 PF12775.7 CEP12085.1 - 1.1e-05 25.0 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 CEP12085.1 - 1.3e-05 25.4 0.1 0.26 11.4 0.0 2.7 2 1 1 3 3 2 2 Dynamin family EF-hand_6 PF13405.6 CEP12085.1 - 2.1e-05 24.1 2.3 0.046 13.7 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain Septin PF00735.18 CEP12085.1 - 2.6e-05 23.6 0.0 0.0083 15.4 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 CEP12085.1 - 4.7e-05 23.2 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CEP12085.1 - 5.5e-05 23.1 0.6 0.085 12.8 0.0 4.0 3 1 0 4 4 4 1 RsgA GTPase AAA_29 PF13555.6 CEP12085.1 - 8.5e-05 22.2 2.0 0.046 13.5 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CEP12085.1 - 8.8e-05 23.1 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CEP12085.1 - 0.0001 22.3 0.0 0.017 15.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SRPRB PF09439.10 CEP12085.1 - 0.00025 20.6 0.0 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 CEP12085.1 - 0.00027 21.3 0.0 1 9.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 CEP12085.1 - 0.0003 21.0 0.0 0.85 9.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CEP12085.1 - 0.00039 20.2 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CEP12085.1 - 0.00046 19.8 0.4 0.44 10.1 0.0 3.4 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.22 CEP12085.1 - 0.0014 17.8 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Ploopntkinase3 PF18751.1 CEP12085.1 - 0.0016 18.4 0.0 0.89 9.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 CEP12085.1 - 0.0017 18.3 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MCM PF00493.23 CEP12085.1 - 0.0022 17.2 0.1 0.1 11.7 0.0 2.6 3 0 0 3 3 2 1 MCM P-loop domain cobW PF02492.19 CEP12085.1 - 0.0023 17.6 0.0 0.76 9.3 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain EF-hand_10 PF14788.6 CEP12085.1 - 0.0031 17.3 3.1 0.057 13.3 0.4 2.5 2 0 0 2 2 2 1 EF hand DUF815 PF05673.13 CEP12085.1 - 0.0034 16.6 0.0 0.52 9.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.20 CEP12085.1 - 0.0037 16.5 0.2 2.8 7.0 0.1 2.7 3 0 0 3 3 2 0 G-protein alpha subunit AAA_17 PF13207.6 CEP12085.1 - 0.0038 17.6 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CEP12085.1 - 0.0051 16.6 0.3 4.6 7.0 0.0 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 CEP12085.1 - 0.007 16.4 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 CEP12085.1 - 0.013 14.4 0.0 0.031 13.2 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 CEP12085.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 CEP12085.1 - 0.016 15.3 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CEP12085.1 - 0.016 14.6 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 CEP12085.1 - 0.016 14.5 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 CEP12085.1 - 0.021 14.3 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Sigma54_activat PF00158.26 CEP12085.1 - 0.026 14.2 0.0 6.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain PduV-EutP PF10662.9 CEP12085.1 - 0.042 13.6 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.21 CEP12085.1 - 0.054 12.9 0.1 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CEP12085.1 - 0.055 13.8 0.0 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CEP12085.1 - 0.082 12.4 0.1 30 4.1 0.0 3.2 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CEP12085.1 - 0.087 12.2 0.2 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_8 PF13833.6 CEP12085.1 - 0.089 12.7 2.2 4.5 7.2 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair VirE PF05272.11 CEP12085.1 - 0.09 12.5 0.1 14 5.4 0.0 2.8 2 1 0 2 2 2 0 Virulence-associated protein E FLgD_tudor PF13861.6 CEP12085.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 FlgD Tudor-like domain SPARC_Ca_bdg PF10591.9 CEP12085.1 - 0.1 12.9 0.5 2.4 8.5 0.1 2.7 2 1 1 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region MobB PF03205.14 CEP12085.1 - 0.11 12.4 0.2 18 5.2 0.0 2.7 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.16 CEP12085.1 - 0.12 11.7 0.0 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 AIG1 family DAP3 PF10236.9 CEP12085.1 - 0.12 11.5 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 EF-hand_5 PF13202.6 CEP12085.1 - 0.14 11.8 6.7 1.5 8.4 0.4 2.6 2 0 0 2 2 2 0 EF hand NTPase_1 PF03266.15 CEP12085.1 - 0.15 12.0 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 CEP12085.1 - 0.15 11.8 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 CEP12085.1 - 0.16 12.5 0.1 30 5.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain Fungal_lectin_2 PF18647.1 CEP12085.1 - 0.17 12.4 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin AAA_30 PF13604.6 CEP12085.1 - 0.17 11.6 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.21 CEP12086.1 - 1.8e-65 220.4 0.3 4.3e-65 219.2 0.3 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CEP12086.1 - 3.9e-45 154.3 0.0 3.9e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CEP12086.1 - 4.2e-26 91.4 0.0 3.3e-25 88.6 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 CEP12086.1 - 0.09 12.8 0.3 15 5.7 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Presenilin PF01080.17 CEP12086.1 - 0.099 11.4 1.8 0.15 10.8 1.8 1.2 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.13 CEP12086.1 - 0.39 10.4 10.6 0.73 9.5 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4778 PF16008.5 CEP12086.1 - 1.9 8.5 9.3 2.6 8.0 2.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4778) DUF2052 PF09747.9 CEP12086.1 - 6.9 6.7 17.3 15 5.6 17.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Dicty_REP PF05086.12 CEP12086.1 - 7.8 4.3 13.3 5.1 4.9 11.4 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.32 CEP12087.1 - 1.3e-16 60.7 7.4 0.00017 22.3 0.5 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12087.1 - 9.9e-07 29.0 0.0 0.12 12.7 0.0 4.0 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEP12087.1 - 0.011 16.2 0.1 3.5 8.2 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 CEP12087.1 - 0.024 14.0 0.4 0.21 10.9 0.2 1.8 1 1 0 1 1 1 0 WD40-like domain UCR_hinge PF02320.16 CEP12089.1 - 9e-23 80.3 6.2 9e-23 80.3 6.2 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein NatB_MDM20 PF09797.9 CEP12089.1 - 0.062 12.2 0.1 0.073 12.0 0.1 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit MtrG PF04210.13 CEP12089.1 - 0.33 10.8 0.8 1.5 8.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G SIR2_2 PF13289.6 CEP12090.1 - 0.14 12.3 0.2 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 SIR2-like domain Cdh1_DBD_1 PF18196.1 CEP12090.1 - 0.66 10.3 4.2 0.7 10.2 3.0 1.7 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 FYRN PF05964.14 CEP12091.1 - 2.2e-21 75.4 0.3 5.6e-21 74.1 0.3 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CEP12091.1 - 5e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus RTBV_P12 PF06361.11 CEP12091.1 - 0.46 10.9 2.2 6.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein DUF2828 PF11443.8 CEP12093.1 - 2.2e-185 617.4 2.8 2.6e-185 617.2 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Rsm22 PF09243.10 CEP12093.1 - 0.031 13.6 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MukF_C PF17193.4 CEP12093.1 - 0.1 12.7 0.9 0.25 11.5 0.9 1.6 1 0 0 1 1 1 0 MukF C-terminal domain zinc_ribbon_6 PF14599.6 CEP12094.1 - 4.8e-25 87.3 1.1 4.8e-25 87.3 1.1 4.7 3 2 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 CEP12094.1 - 7.3e-20 71.2 24.1 7.3e-20 71.2 24.1 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 CEP12094.1 - 1.3e-08 35.0 9.8 1.3e-08 35.0 9.8 5.9 4 2 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP12094.1 - 0.0018 18.1 12.5 0.0018 18.1 12.5 6.4 4 3 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP12094.1 - 0.01 15.8 10.7 0.01 15.8 10.7 4.9 5 1 1 6 6 6 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP12094.1 - 0.016 15.0 9.5 0.016 15.0 9.5 5.9 2 1 4 6 6 6 0 Prokaryotic RING finger family 4 Tcf25 PF04910.14 CEP12095.1 - 7.5e-95 318.0 3.8 1e-94 317.5 3.8 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Wbp11 PF09429.10 CEP12095.1 - 5.9 7.4 11.4 40 4.7 8.2 2.8 2 0 0 2 2 2 0 WW domain binding protein 11 GRASP55_65 PF04495.14 CEP12096.1 - 6e-64 214.5 0.0 1.3e-46 158.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CEP12096.1 - 4.5e-07 29.6 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CEP12096.1 - 2.2e-05 24.7 0.0 0.0046 17.2 0.0 2.2 1 1 1 2 2 2 2 PDZ domain PDZ PF00595.24 CEP12096.1 - 0.0062 16.9 0.0 0.93 9.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain HSP70 PF00012.20 CEP12097.1 - 0.25 9.5 0.0 0.58 8.3 0.0 1.5 2 0 0 2 2 2 0 Hsp70 protein UQ_con PF00179.26 CEP12098.1 - 1.1e-37 128.8 0.1 1.4e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP12098.1 - 0.1 12.9 0.1 0.23 11.7 0.0 1.7 1 1 1 2 2 2 0 RWD domain RVT_1 PF00078.27 CEP12100.1 - 8.7e-32 110.4 0.0 1.2e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L20 PF00453.18 CEP12100.1 - 0.034 14.3 0.5 0.071 13.2 0.2 1.6 1 1 0 1 1 1 0 Ribosomal protein L20 PMR5N PF14416.6 CEP12100.1 - 0.13 12.6 2.8 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 PMR5 N terminal Domain Exo_endo_phos_2 PF14529.6 CEP12101.1 - 3.4e-13 49.5 0.0 1.8e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP12101.1 - 3.8e-06 26.6 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Muted PF14942.6 CEP12101.1 - 0.024 15.0 1.6 0.051 13.9 1.6 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein TSC22 PF01166.18 CEP12101.1 - 0.029 14.7 1.2 0.09 13.1 1.2 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family FAM76 PF16046.5 CEP12101.1 - 0.25 10.7 2.0 0.38 10.0 2.0 1.2 1 0 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 CEP12101.1 - 0.37 11.2 9.1 1 9.8 9.2 1.7 1 1 0 1 1 1 0 Csm1 N-terminal domain CoA_transf_3 PF02515.17 CEP12102.1 - 1.1e-135 452.5 0.0 1.2e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CS PF04969.16 CEP12103.1 - 7.9e-12 46.0 0.1 2.2e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 CS domain Parvo_coat_N PF08398.10 CEP12103.1 - 0.089 13.0 0.3 0.27 11.4 0.3 1.8 1 0 0 1 1 1 0 Parvovirus coat protein VP1 RINT1_TIP1 PF04437.13 CEP12104.1 - 1.1e-111 374.2 12.0 1.1e-111 374.2 12.0 2.2 2 0 0 2 2 2 2 RINT-1 / TIP-1 family Baculo_PEP_C PF04513.12 CEP12104.1 - 5.6 7.0 15.9 3.8 7.5 0.2 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DSPc PF00782.20 CEP12105.1 - 6.4e-30 103.7 0.1 8.9e-30 103.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CEP12105.1 - 0.0019 18.5 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF1473 PF07341.11 CEP12105.1 - 0.038 13.8 0.2 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1473) Y_phosphatase PF00102.27 CEP12105.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MFS_1 PF07690.16 CEP12106.1 - 1.1e-43 149.6 46.8 3.4e-38 131.5 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CEP12106.1 - 0.00011 21.7 4.2 0.00011 21.7 4.2 1.5 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ESSS PF10183.9 CEP12106.1 - 0.41 10.9 1.2 0.97 9.7 0.1 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TPR_1 PF00515.28 CEP12107.1 - 1.3e-09 37.4 2.1 0.0038 17.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12107.1 - 7.4e-09 35.1 1.3 0.0034 17.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP12107.1 - 1.7e-06 27.7 2.6 0.1 12.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 CEP12107.1 - 2.8e-05 23.9 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 CEP12107.1 - 5.1e-05 23.8 0.5 1.7 9.7 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat LRR_6 PF13516.6 CEP12107.1 - 7.3e-05 22.5 7.9 0.037 14.1 0.0 5.6 6 0 0 6 6 5 1 Leucine Rich repeat TPR_16 PF13432.6 CEP12107.1 - 0.00016 22.3 0.7 0.23 12.1 0.6 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP12107.1 - 0.00027 21.2 2.6 0.023 15.0 0.6 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP12107.1 - 0.00027 20.8 0.0 0.33 11.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box PF00646.33 CEP12107.1 - 0.00029 20.7 0.0 0.00084 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 CEP12107.1 - 0.0003 21.1 9.6 2.6 8.6 0.4 5.9 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) TPR_11 PF13414.6 CEP12107.1 - 0.00035 20.2 0.1 0.009 15.7 0.0 2.7 2 1 1 3 3 3 1 TPR repeat M16C_assoc PF08367.11 CEP12107.1 - 0.0092 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated TPR_19 PF14559.6 CEP12107.1 - 0.013 16.0 1.0 0.73 10.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEP12107.1 - 0.086 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12107.1 - 0.1 13.0 0.0 0.97 10.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP12107.1 - 0.13 12.9 4.6 24 5.8 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 CEP12107.1 - 0.63 10.8 6.3 16 6.5 0.0 5.1 4 1 0 4 4 3 0 Leucine Rich Repeat Arrestin_N PF00339.29 CEP12108.1 - 3.6e-11 43.3 0.0 4.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP12108.1 - 0.00016 22.1 1.7 0.0018 18.7 2.2 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 CEP12108.1 - 0.042 13.5 0.0 0.55 9.9 0.0 2.5 2 1 0 2 2 2 0 Arrestin_N terminal like DUF1752 PF08550.10 CEP12109.1 - 1.7e-10 40.6 2.3 3.5e-10 39.5 2.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AbiEii PF08843.11 CEP12109.1 - 0.052 13.5 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system WES_acyltransf PF03007.16 CEP12110.1 - 2.5e-19 70.1 0.2 2.2e-18 67.0 0.2 2.0 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 CEP12110.1 - 1.4e-11 44.5 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 CEP12110.1 - 0.01 14.5 0.0 0.038 12.7 0.0 1.8 2 0 0 2 2 2 0 Condensation domain zf-C2H2 PF00096.26 CEP12111.1 - 6.4e-06 26.3 11.9 0.018 15.5 1.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEP12111.1 - 4.9e-05 23.5 6.5 0.0054 17.0 1.1 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP12111.1 - 0.00096 19.8 16.3 0.0042 17.8 1.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CEP12111.1 - 0.0026 18.1 0.5 0.0026 18.1 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEP12111.1 - 0.0083 16.1 7.6 0.61 10.1 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 CEP12111.1 - 0.21 11.9 5.3 3.2 8.1 0.1 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 CEP12111.1 - 0.47 10.3 3.3 8.7 6.2 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CEP12111.1 - 3.9 8.1 17.0 1.2 9.7 3.5 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Ndc80_HEC PF03801.13 CEP12112.1 - 7.6e-31 106.8 0.5 3.4e-30 104.7 0.3 2.2 1 1 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 CEP12112.1 - 7.4e-05 22.7 0.1 7.4e-05 22.7 0.1 5.8 4 2 2 6 6 6 2 Domain of unknown function (DUF5595) DUF2381 PF09544.10 CEP12112.1 - 0.046 13.2 11.4 0.061 12.8 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) TPR_MLP1_2 PF07926.12 CEP12112.1 - 0.52 10.4 43.9 0.68 10.0 14.3 4.3 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2353 PF09789.9 CEP12112.1 - 0.69 9.2 40.5 1.2 8.4 12.1 3.1 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Phage_GP20 PF06810.11 CEP12112.1 - 0.82 9.5 38.0 0.027 14.3 12.3 4.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 Spc7 PF08317.11 CEP12112.1 - 3.4 6.5 44.5 0.94 8.3 22.7 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 CEP12112.1 - 4.2 7.1 17.6 0.31 10.8 0.2 4.3 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Fez1 PF06818.15 CEP12112.1 - 6.3 7.2 38.2 1.8 8.9 15.7 2.8 2 0 0 2 2 2 0 Fez1 LtuB PF17455.2 CEP12112.1 - 6.8 7.4 9.9 0.41 11.3 0.4 3.5 2 1 1 3 3 3 0 Late transcription unit B UBD PF16455.5 CEP12113.1 - 1e-25 90.0 0.0 1.8e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain ACPS PF01648.20 CEP12113.1 - 4.6e-14 52.5 0.0 2e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF2407 PF10302.9 CEP12113.1 - 0.00045 20.7 0.1 0.00086 19.8 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CEP12113.1 - 0.1 12.4 0.1 0.34 10.7 0.1 1.9 1 0 0 1 1 1 0 Ubiquitin family Amino_oxidase PF01593.24 CEP12116.1 - 5.5e-58 197.3 0.0 2.1e-57 195.4 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP12116.1 - 2.1e-08 34.3 0.2 5.7e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP12116.1 - 7.8e-05 22.0 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP12116.1 - 0.00093 18.9 0.5 0.012 15.2 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP12116.1 - 0.0012 18.2 0.9 0.015 14.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP12116.1 - 0.0045 16.3 0.1 0.0094 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 CEP12116.1 - 0.031 14.5 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 CEP12116.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CEP12116.1 - 0.066 12.3 0.3 0.13 11.4 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CEP12116.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 CEP12116.1 - 0.078 12.3 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.27 CEP12116.1 - 0.093 13.3 0.5 0.57 10.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP12116.1 - 0.13 11.5 0.2 0.33 10.2 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase P_C10 PF14974.6 CEP12116.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein C10 HI0933_like PF03486.14 CEP12116.1 - 0.16 10.6 1.3 0.22 10.2 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein STE PF02200.16 CEP12117.1 - 2.4e-52 176.0 0.0 4.7e-52 175.1 0.0 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 CEP12117.1 - 7.3e-06 26.2 15.9 0.0021 18.4 2.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type IBR PF01485.21 CEP12117.1 - 0.025 14.8 0.3 0.064 13.5 0.3 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-met PF12874.7 CEP12117.1 - 0.057 13.8 0.4 1.7 9.2 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP12117.1 - 0.36 11.8 16.7 0.21 12.5 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 CEP12118.1 - 6.1e-72 242.1 0.4 6.1e-72 242.1 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12118.1 - 5e-52 176.7 0.3 1.1e-51 175.6 0.3 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP12118.1 - 4e-20 71.9 0.2 1.9e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 CEP12118.1 - 2.5e-11 44.0 0.5 6.7e-11 42.6 0.5 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CEP12118.1 - 8.6e-05 22.0 0.1 0.00036 19.9 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP12118.1 - 0.00048 19.0 14.2 0.0053 15.6 14.0 2.7 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP12118.1 - 0.00083 18.4 3.5 0.00083 18.4 3.5 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CEP12118.1 - 0.011 15.7 0.1 5.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH_11 PF15413.6 CEP12118.1 - 0.012 16.1 0.9 0.012 16.1 0.9 3.6 3 2 0 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 CEP12118.1 - 0.039 14.3 2.8 1.1 9.6 0.3 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain Kdo PF06293.14 CEP12118.1 - 0.082 12.2 0.3 0.18 11.1 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_2 PF08458.10 CEP12118.1 - 3.7 8.0 7.9 0.85 10.0 0.2 2.9 3 0 0 3 3 3 0 Plant pleckstrin homology-like region FlxA PF14282.6 CEP12119.1 - 0.023 14.7 3.6 0.029 14.4 3.6 1.2 1 0 0 1 1 1 0 FlxA-like protein Exo_endo_phos PF03372.23 CEP12120.1 - 7.3e-05 22.4 0.4 9.1e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PP2C PF00481.21 CEP12123.1 - 8.1e-76 255.1 0.0 1.1e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CEP12123.1 - 0.00063 19.7 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) dCMP_cyt_deam_1 PF00383.23 CEP12124.1 - 8.3e-26 89.8 0.3 1.2e-25 89.3 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP12124.1 - 1.2e-20 73.6 0.0 1.4e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 CEP12124.1 - 4.9e-05 23.5 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 CEP12124.1 - 7.8e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 CEP12124.1 - 0.0027 17.6 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 CEP12124.1 - 0.0041 17.2 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 CEP12124.1 - 0.0044 17.1 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CEP12124.1 - 0.01 15.9 0.5 0.054 13.6 0.5 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC1 PF18769.1 CEP12124.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 Ncstrn_small PF18266.1 CEP12124.1 - 0.019 15.0 0.0 0.096 12.7 0.0 1.9 2 0 0 2 2 2 0 Nicastrin small lobe NAD2 PF18782.1 CEP12124.1 - 0.047 13.8 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 CEP12124.1 - 0.054 13.4 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Ribonuc_red_lgC PF02867.15 CEP12125.1 - 3.6e-180 600.0 0.0 4.7e-180 599.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEP12125.1 - 3.6e-23 81.4 0.0 9.3e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEP12125.1 - 9.4e-13 48.5 0.3 3.9e-12 46.6 0.1 2.3 2 0 0 2 2 2 1 ATP cone domain DUF3015 PF11220.8 CEP12125.1 - 0.023 14.6 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) PBAN PF05874.11 CEP12125.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) TPR_12 PF13424.6 CEP12126.1 - 2.5e-06 27.7 3.0 0.0083 16.4 0.3 4.2 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12126.1 - 2.5e-05 24.0 10.7 1.5 9.1 0.4 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP12126.1 - 3.9e-05 24.2 0.1 0.33 11.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP12126.1 - 5.3e-05 23.1 7.2 0.056 13.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12126.1 - 0.00016 21.8 0.2 0.59 10.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP12126.1 - 0.00026 21.4 1.3 0.058 13.9 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP12126.1 - 0.0015 19.2 3.8 1.2 10.1 0.0 4.4 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12126.1 - 0.0024 17.6 4.8 15 5.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP12126.1 - 0.0029 17.0 1.2 0.0086 15.5 1.2 1.7 1 1 0 1 1 1 1 MalT-like TPR region ANAPC3 PF12895.7 CEP12126.1 - 0.0029 17.8 3.0 0.49 10.7 0.4 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 CEP12126.1 - 0.0061 15.3 0.0 0.0086 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 CEP12126.1 - 0.15 12.3 0.4 2.5 8.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-bind_6 PF13921.6 CEP12127.1 - 0.0013 18.9 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP12127.1 - 0.0087 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3844 PF12955.7 CEP12128.1 - 3.3e-13 49.7 9.5 8.1e-13 48.4 9.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) DUF3482 PF11981.8 CEP12128.1 - 0.2 11.0 0.1 0.32 10.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) EGF_3 PF12947.7 CEP12128.1 - 0.76 10.0 16.5 1.3 9.3 16.5 1.4 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 CEP12128.1 - 1.5 9.2 17.2 2.7 8.4 17.2 1.4 1 0 0 1 1 1 0 EGF-like domain Coiled-coil_56 PF09813.9 CEP12129.1 - 0.39 10.8 6.3 0.95 9.6 1.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Spc7 PF08317.11 CEP12129.1 - 1.4 7.7 17.8 2.6 6.8 17.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein YqjK PF13997.6 CEP12129.1 - 2.8 8.2 4.6 4.9 7.5 0.4 3.0 2 1 2 4 4 4 0 YqjK-like protein Bcr-Abl_Oligo PF09036.10 CEP12129.1 - 3.5 7.7 7.4 1.5 8.9 0.3 3.3 2 1 2 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain DUF4239 PF14023.6 CEP12129.1 - 4.1 7.1 9.1 15 5.2 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Halogen_Hydrol PF10112.9 CEP12129.1 - 4.7 7.2 8.4 12 5.8 0.5 2.6 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-RING_7 PF02591.15 CEP12130.1 - 0.002 18.2 5.7 0.41 10.9 0.4 3.5 3 0 0 3 3 3 1 C4-type zinc ribbon domain Prok-RING_1 PF14446.6 CEP12130.1 - 0.0056 16.6 1.1 0.0056 16.6 1.1 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-CCHC PF00098.23 CEP12130.1 - 0.018 15.1 4.4 0.22 11.7 0.4 3.8 4 0 0 4 4 4 0 Zinc knuckle zinc_ribbon_2 PF13240.6 CEP12130.1 - 0.049 13.4 6.8 1.4 8.7 0.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Myc_target_1 PF15179.6 CEP12130.1 - 0.072 13.0 4.2 0.44 10.4 0.0 2.0 1 1 1 2 2 2 0 Myc target protein 1 zinc_ribbon_10 PF10058.9 CEP12130.1 - 0.1 12.4 3.3 21 4.9 0.0 3.4 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Nudix_N_2 PF14803.6 CEP12130.1 - 0.18 11.8 10.0 0.33 10.9 0.2 3.6 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 CEP12130.1 - 0.19 11.7 4.4 20 5.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CEP12130.1 - 0.19 11.2 8.3 0.75 9.3 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CEP12130.1 - 0.24 10.9 5.9 18 5.0 0.2 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.19 CEP12130.1 - 0.34 10.7 5.8 1.2 9.0 0.4 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.11 CEP12130.1 - 0.45 10.5 12.3 2.6 8.0 0.8 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.12 CEP12130.1 - 0.54 10.3 5.4 8.2 6.5 0.1 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Ribosomal_L32p PF01783.23 CEP12130.1 - 0.63 10.3 16.8 0.57 10.5 7.2 3.2 3 0 0 3 3 3 0 Ribosomal L32p protein family HypA PF01155.19 CEP12130.1 - 0.74 9.8 13.8 2.6 8.1 1.4 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CEP12130.1 - 1.1 9.5 10.7 2.9 8.1 0.5 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 CEP12130.1 - 1.2 8.8 8.7 9.9 5.9 0.1 3.7 3 1 0 3 3 3 0 Ubiquitin-Binding Zinc Finger YokU PF14122.6 CEP12130.1 - 1.3 9.0 5.9 0.3 11.1 0.2 2.5 2 1 2 4 4 4 0 YokU-like protein, putative antitoxin zf-C2H2_10 PF16588.5 CEP12130.1 - 1.4 8.8 8.3 2.5 7.9 0.6 3.2 2 1 0 2 2 2 0 C2H2 zinc-finger YhfH PF14149.6 CEP12130.1 - 3.8 7.6 7.8 54 3.9 0.7 3.3 3 0 0 3 3 3 0 YhfH-like protein PHD_3 PF13922.6 CEP12130.1 - 4.5 7.7 12.2 2.1 8.8 2.2 3.2 2 1 1 3 3 3 0 PHD domain of transcriptional enhancer, Asx PHD PF00628.29 CEP12130.1 - 8.4 6.4 16.3 4.3 7.3 1.1 4.0 3 2 0 3 3 3 0 PHD-finger DZR PF12773.7 CEP12130.1 - 10 6.3 16.3 0.58 10.2 1.6 3.3 1 1 1 2 2 1 0 Double zinc ribbon PDEase_II PF02112.15 CEP12131.1 - 0.037 13.2 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Helitron_like_N PF14214.6 CEP12132.1 - 2e-13 51.0 0.0 3.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.27 CEP12136.1 - 1.7e-06 27.7 0.1 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP12137.1 - 9.2e-05 22.1 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP12137.1 - 0.002 18.0 1.6 0.0058 16.5 0.2 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase IL23 PF16649.5 CEP12137.1 - 0.025 14.6 0.7 3.1 7.8 0.0 3.3 2 1 1 3 3 3 0 Interleukin 23 subunit alpha DUF4363 PF14276.6 CEP12137.1 - 0.14 12.3 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) GCR1_C PF12550.8 CEP12137.1 - 0.32 11.4 3.0 9.6 6.6 0.1 2.4 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes Osmo_CC PF08946.10 CEP12137.1 - 4.1 7.7 4.9 38 4.6 1.5 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Spectrin PF00435.21 CEP12139.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Spectrin repeat DUF3287 PF11690.8 CEP12139.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) NEMO PF11577.8 CEP12139.1 - 0.1 12.6 1.0 0.19 11.8 1.0 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO TMF_DNA_bd PF12329.8 CEP12139.1 - 0.11 12.5 1.1 0.25 11.4 1.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MerR-DNA-bind PF09278.11 CEP12139.1 - 0.19 12.3 1.1 0.35 11.4 1.1 1.4 1 0 0 1 1 1 0 MerR, DNA binding AAA PF00004.29 CEP12140.1 - 1.2e-12 48.4 0.0 3.4e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEP12140.1 - 2.8e-09 37.2 0.6 4.6e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 CEP12140.1 - 4.3e-06 27.0 0.0 2.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CEP12140.1 - 1.7e-05 24.8 0.0 6.4e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEP12140.1 - 1.9e-05 24.7 0.0 6e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP12140.1 - 2.8e-05 23.9 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CEP12140.1 - 0.00034 20.8 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CEP12140.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP12140.1 - 0.0018 18.7 0.0 0.01 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CEP12140.1 - 0.002 18.7 0.8 0.0079 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEP12140.1 - 0.0028 16.9 0.0 0.0099 15.1 0.0 2.0 1 0 0 1 1 1 1 NB-ARC domain DNA_topoisoIV PF00521.20 CEP12140.1 - 0.004 16.1 5.0 0.011 14.7 1.0 2.3 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A Zeta_toxin PF06414.12 CEP12140.1 - 0.0049 16.2 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 CEP12140.1 - 0.0072 16.9 3.8 0.078 13.5 0.3 3.2 2 1 0 2 2 2 1 ABC transporter TIP49 PF06068.13 CEP12140.1 - 0.014 14.6 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 CEP12140.1 - 0.016 14.3 0.1 0.061 12.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CEP12140.1 - 0.022 14.7 0.0 0.082 12.8 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CEP12140.1 - 0.022 14.7 0.1 0.32 10.9 0.1 2.5 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CEP12140.1 - 0.029 14.8 0.1 0.029 14.8 0.1 3.4 3 1 1 4 4 3 0 AAA domain TsaE PF02367.17 CEP12140.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CEP12140.1 - 0.049 13.4 0.1 0.25 11.0 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CEP12140.1 - 0.053 13.4 0.9 0.63 9.9 0.1 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 CEP12140.1 - 0.058 13.8 0.0 0.35 11.3 0.0 2.4 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CEP12140.1 - 0.061 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CEP12140.1 - 0.076 13.3 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CEP12140.1 - 0.19 11.3 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4110 PF13422.6 CEP12140.1 - 2.8 8.1 11.1 0.61 10.2 7.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4110) WLM PF08325.10 CEP12141.1 - 2.9e-37 128.6 0.2 4e-37 128.2 0.2 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 CEP12141.1 - 7.1e-10 38.0 14.0 4.8e-05 22.6 6.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 CEP12141.1 - 0.0058 16.7 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.7 CEP12141.1 - 0.02 14.9 9.4 0.02 14.9 9.4 1.7 2 0 0 2 2 2 0 Double zinc ribbon SprT-like PF10263.9 CEP12141.1 - 0.069 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 SprT-like family PhnA_Zn_Ribbon PF08274.12 CEP12141.1 - 0.28 11.2 3.2 0.45 10.5 0.6 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon OrfB_Zn_ribbon PF07282.11 CEP12141.1 - 3 7.8 6.5 19 5.3 1.4 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 CEP12141.1 - 4 7.6 13.9 5.3 7.2 3.7 3.2 1 1 3 4 4 4 0 Sec23/Sec24 zinc finger Sulfate_transp PF00916.20 CEP12142.1 - 6.9e-62 209.4 22.5 1.1e-61 208.7 22.5 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CEP12142.1 - 1.2e-14 54.1 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CEP12142.1 - 1.7e-10 40.6 0.0 3.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain SpoIIE PF07228.12 CEP12144.1 - 1.4e-12 47.9 0.0 3e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CEP12144.1 - 1.6e-08 34.5 0.2 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CEP12144.1 - 4.8e-08 32.9 0.0 7.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Mur_ligase_M PF08245.12 CEP12145.1 - 8.1e-11 42.3 0.0 2.7e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CEP12145.1 - 1.4e-05 25.2 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain tRNA_U5-meth_tr PF05958.11 CEP12145.1 - 0.067 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_primase_S PF01896.19 CEP12146.1 - 2.3e-58 197.2 1.9 4.3e-58 196.3 1.9 1.5 1 0 0 1 1 1 1 DNA primase small subunit DUF647 PF04884.14 CEP12146.1 - 3.1e-54 184.1 0.2 4.6e-54 183.6 0.2 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis ZoocinA_TRD PF16775.5 CEP12147.1 - 0.079 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme Chromo PF00385.24 CEP12149.1 - 0.006 16.5 0.5 0.0064 16.4 0.5 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnn_1N PF07989.11 CEP12153.1 - 3.3e-20 72.0 5.3 3.3e-20 72.0 5.3 10.3 3 1 4 8 8 8 2 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 CEP12153.1 - 0.02 15.8 5.3 0.02 15.8 5.3 7.8 1 1 6 7 7 7 0 cGMP-dependent protein kinase interacting domain AAA_6 PF12774.7 CEP12154.1 - 3.8e-131 436.9 0.1 6.2e-129 429.7 0.0 3.6 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CEP12154.1 - 1e-122 410.6 14.7 1e-122 410.6 14.7 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CEP12154.1 - 3.3e-118 395.3 5.6 3.3e-118 395.3 5.6 6.4 6 2 1 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CEP12154.1 - 7e-76 254.2 0.3 7e-76 254.2 0.3 4.6 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 CEP12154.1 - 4.7e-68 229.3 0.0 2.2e-67 227.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CEP12154.1 - 3.7e-48 164.3 1.0 2e-47 161.9 1.2 2.3 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CEP12154.1 - 1.2e-41 142.2 0.0 5.8e-35 120.4 0.0 5.1 6 0 0 6 6 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CEP12154.1 - 1.6e-38 132.1 0.0 3.8e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CEP12154.1 - 5.9e-31 107.0 0.0 1e-28 99.8 0.0 4.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CEP12154.1 - 1.2e-30 106.8 18.0 8e-20 71.1 0.0 3.0 2 1 0 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CEP12154.1 - 6.8e-29 100.6 0.0 3.8e-12 46.4 0.0 6.5 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CEP12154.1 - 9.9e-20 70.9 0.3 1.6e-18 67.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CEP12154.1 - 3.8e-15 56.4 0.1 0.0045 17.3 0.0 5.7 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 CEP12154.1 - 3.9e-13 50.0 0.0 0.012 16.1 0.0 5.7 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEP12154.1 - 3.8e-11 43.3 0.6 0.03 14.5 0.0 5.5 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 CEP12154.1 - 7e-09 36.3 0.0 0.73 10.2 0.0 5.9 5 0 0 5 5 5 2 AAA ATPase domain T2SSE PF00437.20 CEP12154.1 - 6.1e-07 28.8 0.0 0.025 13.6 0.0 4.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 CEP12154.1 - 6.3e-07 30.0 6.0 0.23 12.0 0.0 6.1 6 0 0 6 6 5 2 AAA domain AAA_lid_1 PF17857.1 CEP12154.1 - 3.2e-06 27.3 0.0 3.1e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 CEP12154.1 - 4.1e-06 26.3 0.0 0.39 10.0 0.0 4.5 4 0 0 4 4 4 2 FtsK/SpoIIIE family AAA_29 PF13555.6 CEP12154.1 - 4.1e-06 26.4 0.1 0.33 10.7 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CEP12154.1 - 4.5e-06 26.2 0.3 0.87 8.9 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CEP12154.1 - 5.2e-06 27.0 0.0 0.64 10.5 0.0 5.2 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 CEP12154.1 - 5.3e-05 23.0 0.3 9.9 5.8 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 CEP12154.1 - 0.00022 21.6 1.0 0.31 11.4 0.0 4.7 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 CEP12154.1 - 0.00034 20.6 0.0 7.6 6.4 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain IstB_IS21 PF01695.17 CEP12154.1 - 0.00091 19.0 0.4 0.54 10.0 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 CEP12154.1 - 0.0013 18.5 0.7 41 3.8 0.0 5.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CEP12154.1 - 0.0019 18.5 0.0 2.9 8.3 0.0 4.5 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.6 CEP12154.1 - 0.012 15.2 0.0 0.42 10.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 CEP12154.1 - 0.018 15.0 1.4 55 3.6 0.1 4.4 4 0 0 4 4 3 0 NACHT domain POT1PC PF16686.5 CEP12154.1 - 0.037 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DUF948 PF06103.11 CEP12154.1 - 6.5 7.1 7.3 32 4.9 0.3 5.8 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) HLH PF00010.26 CEP12156.1 - 5.3e-17 61.5 0.9 5.3e-17 61.5 0.9 2.3 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1978 PF09321.10 CEP12156.1 - 0.0039 16.5 1.8 0.0062 15.9 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) DOCK-C2 PF14429.6 CEP12156.1 - 0.012 15.5 0.9 0.021 14.6 0.9 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Lem_TRP PF08262.11 CEP12156.1 - 1.4 9.1 3.6 2.8 8.1 0.3 2.5 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide DUF4666 PF15697.5 CEP12156.1 - 1.6 9.4 7.0 1.7 9.4 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4666) GCN5L1 PF06320.13 CEP12156.1 - 2.5 8.3 7.2 0.59 10.3 1.4 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Pkinase PF00069.25 CEP12158.1 - 1.9e-52 178.2 0.0 3.6e-52 177.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12158.1 - 9.3e-20 71.0 0.1 3.6e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CEP12158.1 - 0.0012 18.8 0.9 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP12158.1 - 0.02 14.2 0.3 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 CEP12158.1 - 0.048 13.2 0.5 0.16 11.6 0.1 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase MscS_TM PF12794.7 CEP12158.1 - 8.8 5.1 5.6 25 3.6 5.6 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FYVE PF01363.21 CEP12159.1 - 3.6e-13 49.4 11.4 3.6e-13 49.4 11.4 2.6 3 0 0 3 3 3 1 FYVE zinc finger CreD PF06123.12 CEP12159.1 - 0.2 10.4 1.1 0.41 9.4 1.1 1.6 1 1 0 1 1 1 0 Inner membrane protein CreD TEA PF01285.18 CEP12160.1 - 4e-31 106.9 0.0 9.7e-31 105.7 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain YBD PF17725.1 CEP12160.1 - 2.3e-08 34.2 0.5 5e-08 33.1 0.5 1.6 1 0 0 1 1 1 1 YAP binding domain CLASP_N PF12348.8 CEP12161.1 - 1.2e-54 185.2 0.1 2.1e-54 184.5 0.1 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 CEP12161.1 - 0.013 15.7 0.0 8.1 7.0 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF3866 PF12982.7 CEP12161.1 - 0.41 9.7 1.8 0.83 8.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) SUIM_assoc PF16619.5 CEP12161.1 - 3.4 7.8 9.4 0.32 11.1 1.8 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 V-SNARE PF05008.15 CEP12162.1 - 1.2e-08 35.2 0.6 1.4e-08 35.0 0.6 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus PAP1 PF08601.10 CEP12162.1 - 0.043 13.6 0.3 0.048 13.4 0.3 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 V-SNARE_C PF12352.8 CEP12163.1 - 2.5e-19 69.3 3.0 4.6e-19 68.5 3.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CEP12163.1 - 6.4e-09 36.1 3.3 1.1e-07 32.2 1.0 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus SNARE PF05739.19 CEP12163.1 - 5.2e-05 23.2 0.9 5.2e-05 23.2 0.9 1.6 2 0 0 2 2 2 1 SNARE domain Fusion_gly PF00523.18 CEP12163.1 - 0.0044 15.3 0.8 0.0066 14.8 0.8 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 DUF4407 PF14362.6 CEP12163.1 - 0.01 15.2 0.6 0.013 14.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 CEP12163.1 - 0.056 13.4 0.2 0.11 12.4 0.2 1.6 1 1 0 1 1 1 0 Sec20 RIFIN PF02009.16 CEP12163.1 - 0.098 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Rifin Ribosomal_S8 PF00410.19 CEP12163.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S8 CortBP2 PF09727.9 CEP12163.1 - 0.45 10.4 4.9 1.4 8.8 0.2 2.5 2 1 0 3 3 3 0 Cortactin-binding protein-2 Synaptobrevin PF00957.21 CEP12163.1 - 0.5 10.2 4.1 0.67 9.8 0.4 2.6 3 0 0 3 3 3 0 Synaptobrevin Flp1_like PF16982.5 CEP12163.1 - 2.3 7.7 7.5 4.3 6.8 7.5 1.4 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Rad51 PF08423.11 CEP12164.1 - 1.2e-122 408.1 0.3 1.5e-122 407.7 0.3 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CEP12164.1 - 1.7e-10 40.8 0.2 2.4e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CEP12164.1 - 4.8e-10 39.3 0.0 7.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEP12164.1 - 1.2e-07 31.4 0.1 2e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CEP12164.1 - 0.00013 22.5 0.1 0.00034 21.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 CEP12164.1 - 0.0013 18.1 0.1 0.034 13.5 0.1 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 CEP12164.1 - 0.071 12.2 0.4 0.44 9.6 0.2 1.9 2 0 0 2 2 2 0 PAXNEB protein AAA_22 PF13401.6 CEP12164.1 - 0.076 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 CEP12165.1 - 3.5e-09 36.6 13.8 3.5e-09 36.6 13.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bestrophin PF01062.21 CEP12168.1 - 4.2e-41 141.3 0.1 3.7e-26 92.2 0.0 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SR-25 PF10500.9 CEP12168.1 - 0.021 14.4 2.0 0.03 13.9 2.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4239 PF14023.6 CEP12168.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3464 PF11947.8 CEP12168.1 - 2.2 8.0 4.3 5.7 6.7 0.8 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 FHA PF00498.26 CEP12170.1 - 4.4e-16 59.0 0.0 6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEP12170.1 - 0.00041 20.6 0.0 0.00057 20.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CEP12170.1 - 0.0029 17.8 0.1 0.0036 17.5 0.1 1.3 1 1 0 1 1 1 1 FHA domain EI24 PF07264.11 CEP12171.1 - 0.64 10.2 5.0 0.92 9.7 5.0 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) B56 PF01603.20 CEP12172.1 - 2.4e-189 629.6 8.2 2.9e-189 629.3 8.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF5523 PF17661.1 CEP12172.1 - 0.65 9.6 10.9 1.1 8.8 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ecm29 PF13001.7 CEP12173.1 - 8.7e-145 483.2 3.8 2.1e-144 481.9 0.1 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 CEP12173.1 - 4.8e-10 38.8 18.2 0.036 14.3 0.0 11.8 13 0 0 13 13 12 2 HEAT repeat HEAT_2 PF13646.6 CEP12173.1 - 6.3e-10 39.3 1.2 0.8 10.1 0.0 7.9 7 2 0 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 CEP12173.1 - 1.1e-06 29.0 6.0 13 6.4 0.0 8.6 9 0 0 9 9 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEP12173.1 - 1.6e-06 28.6 4.3 0.35 11.5 0.0 7.1 7 2 2 10 10 9 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 CEP12173.1 - 2.7e-06 26.7 10.6 0.16 11.0 0.0 6.4 4 2 4 8 8 8 3 Interferon-related developmental regulator (IFRD) Dopey_N PF04118.14 CEP12173.1 - 0.011 14.9 0.2 0.057 12.5 0.2 2.4 2 0 0 2 2 2 0 Dopey, N-terminal DNA_alkylation PF08713.11 CEP12173.1 - 0.012 15.3 0.2 0.11 12.2 0.1 2.7 2 0 0 2 2 2 0 DNA alkylation repair enzyme Helicase_C_3 PF13625.6 CEP12173.1 - 0.033 14.3 0.0 3.3 7.9 0.0 3.6 3 0 0 3 3 3 0 Helicase conserved C-terminal domain SBP_bac_8 PF13416.6 CEP12173.1 - 0.1 12.4 0.2 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Arm PF00514.23 CEP12173.1 - 0.13 12.3 0.0 2.3 8.4 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CEP12173.1 - 0.23 11.0 7.3 2.1 7.9 0.0 5.4 6 1 0 6 6 6 0 CLASP N terminal NOC3p PF07540.11 CEP12173.1 - 0.27 11.7 2.7 4.6 7.8 0.1 3.6 3 0 0 3 3 3 0 Nucleolar complex-associated protein HLH PF00010.26 CEP12174.1 - 1.2e-08 34.8 0.1 2.2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RVT_1 PF00078.27 CEP12175.1 - 8.3e-22 77.8 0.0 7.8e-14 51.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) S4 PF01479.25 CEP12175.1 - 1.8e-14 53.1 0.0 3.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CEP12175.1 - 0.0062 16.3 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain MatE PF01554.18 CEP12176.1 - 1.3e-55 187.4 28.5 3e-31 108.2 8.1 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CEP12176.1 - 6.8e-09 35.9 9.3 6.8e-09 35.9 9.3 3.5 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 CEP12176.1 - 0.0021 18.2 0.2 0.0052 16.9 0.2 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus LCAT PF02450.15 CEP12178.1 - 1.4e-79 268.1 0.0 1.1e-78 265.1 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase NUDIX PF00293.28 CEP12179.1 - 3.2e-15 56.3 0.0 6.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 CEP12179.1 - 4.7e-11 42.8 1.3 8.7e-08 32.4 0.1 2.6 1 1 1 2 2 2 2 Dcp2, box A domain HSDR_N_2 PF13588.6 CEP12180.1 - 0.0023 17.9 0.1 0.0044 17.0 0.1 1.6 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) PCRF PF03462.18 CEP12181.1 - 5.1e-58 196.1 0.1 5.1e-58 196.1 0.1 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CEP12181.1 - 2.3e-40 137.1 4.3 4.3e-40 136.3 4.3 1.5 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 CEP12181.1 - 0.071 13.4 0.1 0.071 13.4 0.1 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain HalX PF08663.10 CEP12181.1 - 1.8 9.0 6.1 12 6.3 1.4 3.1 3 0 0 3 3 3 0 HalX domain Kinesin PF00225.23 CEP12182.1 - 4.5e-112 374.3 2.1 4.5e-112 374.3 2.1 2.5 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP12182.1 - 9e-29 100.3 0.2 6.5e-28 97.5 0.2 2.6 1 0 0 1 1 1 1 Microtubule binding TFA2_Winged_2 PF18121.1 CEP12182.1 - 9.8 6.0 9.6 2.9 7.7 2.5 3.9 4 2 0 4 4 4 0 TFA2 Winged helix domain 2 Kinase-PolyVal PF18762.1 CEP12183.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Cwf_Cwc_15 PF04889.12 CEP12183.1 - 0.3 10.8 8.8 0.55 9.9 8.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4604 PF15377.6 CEP12183.1 - 4.7 7.6 7.8 1.4e+02 2.9 7.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) F-box-like PF12937.7 CEP12184.1 - 0.001 18.9 1.3 0.0018 18.1 1.3 1.5 1 0 0 1 1 1 1 F-box-like IMS PF00817.20 CEP12185.1 - 1.9e-35 122.1 0.0 3.2e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 CEP12185.1 - 8.5e-13 47.7 0.1 2.4e-12 46.2 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 CEP12185.1 - 1.4e-11 45.1 0.0 2e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEP12185.1 - 0.068 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif SR-25 PF10500.9 CEP12185.1 - 0.12 12.0 6.1 0.25 10.9 6.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SH3_9 PF14604.6 CEP12186.1 - 6.2e-10 38.8 0.0 9.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP12186.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Herpes_gE PF02480.16 CEP12186.1 - 0.00094 18.0 0.0 0.0041 15.9 0.0 1.7 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 CEP12186.1 - 0.0039 16.1 1.3 0.0056 15.6 1.3 1.3 1 1 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 CEP12186.1 - 0.006 17.4 0.1 0.052 14.4 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Alpha_GJ PF03229.13 CEP12186.1 - 0.024 15.2 8.0 0.024 15.2 8.0 3.0 2 1 1 3 3 3 0 Alphavirus glycoprotein J Insulin_TMD PF17870.1 CEP12186.1 - 0.027 14.6 0.5 0.058 13.5 0.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Shisa PF13908.6 CEP12186.1 - 0.21 11.8 13.5 0.17 12.2 1.2 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FeoB_associated PF12669.7 CEP12186.1 - 0.35 11.3 2.6 6.7 7.2 1.1 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein HemX PF04375.14 CEP12186.1 - 0.36 10.1 8.2 0.043 13.1 0.9 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2749 PF10907.8 CEP12186.1 - 0.51 10.5 5.8 14 6.0 2.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) Ribosomal_S20p PF01649.18 CEP12186.1 - 2.6 8.7 9.0 0.17 12.5 3.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S20 zf-C2H2_aberr PF17017.5 CEP12187.1 - 3.4e-06 27.3 4.4 0.026 14.6 0.8 2.6 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CEP12187.1 - 1.8e-05 24.9 12.3 0.019 15.4 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP12187.1 - 0.0059 17.3 14.5 0.044 14.6 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP12187.1 - 0.13 12.8 12.4 0.44 11.1 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CEP12187.1 - 0.85 9.3 9.2 8.6 6.1 0.2 3.3 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain CPSase_L_D2 PF02786.17 CEP12188.1 - 2e-113 377.1 0.5 4e-84 281.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CEP12188.1 - 3.5e-48 162.6 0.0 8.4e-48 161.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CEP12188.1 - 2.2e-46 158.0 0.0 4.6e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CEP12188.1 - 2.8e-44 150.7 0.0 6.3e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CEP12188.1 - 5.2e-40 136.6 0.0 1.8e-39 134.9 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CEP12188.1 - 1.1e-33 116.5 0.0 6.3e-33 114.1 0.0 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CEP12188.1 - 6.6e-19 67.9 0.0 3.6e-18 65.5 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CEP12188.1 - 3.5e-18 65.9 1.8 2.2e-10 40.4 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEP12188.1 - 1.4e-15 57.3 0.2 1.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CEP12188.1 - 1.8e-09 37.4 0.0 0.0003 20.5 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CEP12188.1 - 3.8e-07 30.3 2.1 0.0043 17.1 0.1 3.5 4 0 0 4 4 4 2 ATP-grasp domain Peptidase_C26 PF07722.13 CEP12188.1 - 0.00012 21.9 0.2 0.0063 16.3 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 MULE PF10551.9 CEP12189.1 - 0.0026 18.1 0.1 0.0077 16.6 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain TOPRIM_C PF16898.5 CEP12191.1 - 0.0092 16.3 3.6 0.011 15.9 3.6 1.2 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM ADH_N PF08240.12 CEP12194.1 - 6.7e-31 106.4 2.9 6.7e-31 106.4 2.9 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP12194.1 - 7.8e-18 64.7 0.1 1.4e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEP12194.1 - 1e-11 44.7 0.1 1.6e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 CEP12194.1 - 0.00053 18.8 0.4 0.00082 18.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CEP12194.1 - 0.00066 19.0 0.5 0.0015 17.9 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CEP12194.1 - 0.00084 18.7 0.4 0.0043 16.3 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain ADH_zinc_N_2 PF13602.6 CEP12194.1 - 0.0017 19.4 0.0 0.0058 17.7 0.0 1.9 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 CEP12194.1 - 0.0025 18.3 0.1 0.0055 17.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CEP12194.1 - 0.007 16.8 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CEP12194.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase YdfZ PF14001.6 CEP12194.1 - 0.028 14.8 0.1 0.13 12.7 0.0 2.1 2 1 0 2 2 1 0 YdfZ protein Pyr_redox_2 PF07992.14 CEP12194.1 - 0.033 13.4 0.2 0.063 12.5 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 CEP12194.1 - 0.047 14.2 0.1 0.44 11.0 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 CEP12194.1 - 0.049 13.9 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP12194.1 - 0.066 12.8 0.3 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP12194.1 - 0.19 11.0 0.7 0.29 10.4 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 CEP12195.1 - 1.8e-14 53.5 8.6 1.1e-11 44.3 4.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP12195.1 - 0.00019 20.5 2.2 0.00029 19.9 2.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YbhQ PF11076.8 CEP12195.1 - 0.005 16.8 0.2 0.0092 16.0 0.2 1.4 1 0 0 1 1 1 1 Putative inner membrane protein YbhQ GCP_N_terminal PF17681.1 CEP12196.1 - 4.9e-30 105.2 2.9 4.9e-30 105.2 2.9 2.4 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEP12196.1 - 2.1e-27 96.4 8.4 5.6e-27 95.0 8.4 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Adeno_E1B_19K PF01691.16 CEP12196.1 - 0.0065 16.0 0.7 2.6 7.6 0.1 3.1 2 0 0 2 2 2 2 Adenovirus E1B 19K protein / small t-antigen YvfG PF09628.10 CEP12196.1 - 0.063 13.6 0.5 5.7 7.4 0.1 3.4 1 1 2 3 3 3 0 YvfG protein HTH_46 PF15977.5 CEP12196.1 - 0.066 13.2 1.7 0.25 11.4 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding DUF4611 PF15387.6 CEP12196.1 - 9.9 6.5 7.6 15 5.9 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ribosomal_L30 PF00327.20 CEP12197.1 - 6.5e-12 45.1 0.1 9.1e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e nsp8 PF08717.10 CEP12198.1 - 0.12 12.2 1.8 0.2 11.5 1.8 1.3 1 0 0 1 1 1 0 nsp8 replicase RVT_1 PF00078.27 CEP12199.1 - 2.6e-31 108.9 0.1 5.9e-31 107.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP12199.1 - 5.1e-07 29.6 0.7 5.1e-07 29.6 0.7 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP12199.1 - 6.5e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.6 CEP12199.1 - 0.39 10.5 6.5 0.25 11.1 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP12199.1 - 4.5 7.5 19.2 0.3 11.2 2.8 2.6 2 0 0 2 2 2 0 Zinc knuckle Polysacc_deac_1 PF01522.21 CEP12201.1 - 1.5e-36 125.1 0.0 3.8e-36 123.7 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide deacetylase TRAM_LAG1_CLN8 PF03798.16 CEP12201.1 - 2.6e-36 125.2 23.0 4.6e-36 124.4 23.0 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 CEP12201.1 - 7.5e-15 54.3 0.5 2.1e-14 52.9 0.5 1.8 1 0 0 1 1 1 1 TRAM1-like protein Glyco_hydro_57 PF03065.15 CEP12201.1 - 9.4e-06 25.0 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 TLP-20 PF06088.11 CEP12201.1 - 0.053 13.4 11.4 0.81 9.5 3.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) nec1 PF10379.9 CEP12201.1 - 0.084 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 Zip PF02535.22 CEP12201.1 - 0.24 10.6 3.0 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4834 PF16118.5 CEP12201.1 - 0.99 10.4 0.0 0.99 10.4 0.0 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) GCS PF03074.16 CEP12203.1 - 2.2e-180 599.8 0.0 3.4e-180 599.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 CEP12203.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) LRR_4 PF12799.7 CEP12204.1 - 7.8e-05 23.0 0.4 0.32 11.5 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP12204.1 - 0.002 17.8 2.8 1.4 8.7 0.1 4.2 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.6 CEP12204.1 - 1.6 8.9 10.1 13 6.2 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat EF-hand_6 PF13405.6 CEP12205.1 - 0.14 12.2 0.6 1.2 9.3 0.4 2.7 2 0 0 2 2 2 0 EF-hand domain Synaptobrevin PF00957.21 CEP12206.1 - 1.1 9.1 3.4 9.6 6.1 0.6 2.7 2 0 0 2 2 2 0 Synaptobrevin GalP_UDP_transf PF01087.22 CEP12207.1 - 7.6e-71 238.3 2.6 2.5e-70 236.7 0.8 2.4 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CEP12207.1 - 9.4e-63 210.9 0.0 1.7e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 CEP12207.1 - 2.2e-05 24.9 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEP12207.1 - 0.00064 20.4 0.0 0.0034 18.1 0.0 2.0 2 0 0 2 2 2 1 HIT domain DUF4931 PF16285.5 CEP12207.1 - 0.032 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) DUF4921 PF16268.5 CEP12207.1 - 0.14 11.0 0.4 7.7 5.2 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4921) Fungal_trans PF04082.18 CEP12208.1 - 1.7e-19 69.9 0.6 4.2e-19 68.6 0.3 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP12208.1 - 1.6e-07 31.3 12.0 2.7e-07 30.6 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pap_E4 PF02711.14 CEP12208.1 - 4 8.5 7.1 1.8 9.6 4.1 2.0 2 0 0 2 2 2 0 E4 protein bVLRF1 PF18826.1 CEP12209.1 - 1.1e-58 197.3 0.5 3.7e-58 195.6 0.5 1.9 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CEP12209.1 - 6.5e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BURP PF03181.15 CEP12209.1 - 0.031 13.9 0.2 0.075 12.6 0.2 1.7 1 0 0 1 1 1 0 BURP domain Ank PF00023.30 CEP12209.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeat Cyclin PF08613.11 CEP12210.1 - 1.8e-40 138.9 1.0 2.4e-40 138.5 1.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP12210.1 - 0.012 15.3 1.2 0.023 14.4 1.2 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF1065 PF06358.11 CEP12210.1 - 0.029 14.3 0.0 0.06 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1065) Cnd1_N PF12922.7 CEP12210.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term TIP41 PF04176.13 CEP12211.1 - 3.3e-65 218.8 1.6 4.1e-65 218.4 1.6 1.1 1 0 0 1 1 1 1 TIP41-like family ATE_C PF04377.15 CEP12212.1 - 1.1e-52 178.1 5.4 2.1e-52 177.3 5.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CEP12212.1 - 2.4e-30 104.8 3.0 6.6e-30 103.3 2.9 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus PhyH PF05721.13 CEP12213.1 - 1.1e-09 38.9 0.1 1.7e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sec1 PF00995.23 CEP12214.1 - 1.7e-135 453.5 5.2 1.9e-135 453.3 5.2 1.0 1 0 0 1 1 1 1 Sec1 family Phage_int_SAM_1 PF02899.17 CEP12215.1 - 0.0033 17.7 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP12215.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain N-glycanase_C PF09113.10 CEP12215.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal DASH_Ask1 PF08655.10 CEP12216.1 - 5.4e-19 67.8 0.2 1.1e-18 66.9 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 ERG4_ERG24 PF01222.17 CEP12217.1 - 2e-155 517.8 8.9 2.8e-155 517.3 8.9 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DnaJ PF00226.31 CEP12217.1 - 4.7e-16 58.7 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1295 PF06966.12 CEP12217.1 - 6e-05 22.7 0.2 0.00013 21.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Aldedh PF00171.22 CEP12218.1 - 3.8e-187 622.4 0.1 4.4e-187 622.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP12218.1 - 0.00042 19.8 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) ApoLp-III PF07464.11 CEP12218.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ribosomal_S27 PF01599.19 CEP12219.1 - 1.6e-27 95.4 2.2 5.1e-27 93.8 2.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 CEP12219.1 - 2.5e-19 68.8 0.0 4.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP12219.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CEP12219.1 - 0.0084 16.1 0.1 6.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain IBR PF01485.21 CEP12219.1 - 0.011 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TPR_1 PF00515.28 CEP12220.1 - 2.5e-25 87.2 18.2 1.2e-05 24.9 0.3 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12220.1 - 9.4e-21 72.2 16.6 0.00039 20.3 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat STI1 PF17830.1 CEP12220.1 - 9.3e-18 63.9 6.4 2.2e-17 62.7 6.4 1.7 1 0 0 1 1 1 1 STI1 domain TPR_12 PF13424.6 CEP12220.1 - 4.3e-15 55.7 12.1 1.5e-09 38.0 0.3 5.1 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP12220.1 - 3.4e-12 45.8 15.9 0.00051 19.7 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_8 PF13181.6 CEP12220.1 - 3e-10 39.5 21.7 0.0016 18.5 0.3 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP12220.1 - 1.5e-08 34.1 7.2 3.5e-05 23.5 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP12220.1 - 1.1e-07 32.1 2.1 8.9 7.4 0.0 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12220.1 - 1.8e-07 31.0 9.3 0.098 13.1 0.1 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP12220.1 - 4.3e-06 26.9 8.9 0.013 15.7 0.6 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEP12220.1 - 8.1e-06 26.3 10.2 0.098 13.2 0.1 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP12220.1 - 2.7e-05 23.9 4.9 0.027 14.3 0.3 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP12220.1 - 0.01 16.4 5.0 1.6 9.5 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP12220.1 - 0.01 16.5 5.8 27 5.5 0.6 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat Peptidase_M74 PF03411.13 CEP12220.1 - 0.012 15.2 0.2 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase EF-hand_14 PF17959.1 CEP12220.1 - 0.035 14.5 1.3 7.4 7.0 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain TPR_21 PF09976.9 CEP12220.1 - 0.073 12.8 9.5 0.44 10.2 0.2 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 CEP12220.1 - 0.093 12.9 0.2 1.3 9.3 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat PIN_12 PF16289.5 CEP12220.1 - 0.38 11.2 5.6 5.8 7.4 0.2 2.6 2 0 0 2 2 2 0 PIN domain DUF3109 PF11307.8 CEP12220.1 - 1.8 8.3 6.2 1.2 8.9 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3109) RPN7 PF10602.9 CEP12220.1 - 2.2 7.9 7.4 0.84 9.3 0.1 3.0 1 1 2 3 3 3 0 26S proteasome subunit RPN7 DUF5476 PF17570.2 CEP12221.1 - 0.047 14.1 0.3 0.047 14.1 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Pkinase PF00069.25 CEP12223.1 - 4e-71 239.5 0.0 9.9e-71 238.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12223.1 - 2.1e-40 138.6 0.0 4.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP12223.1 - 6e-06 25.8 0.0 3.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP12223.1 - 0.034 12.9 2.2 0.21 10.3 0.0 2.5 2 0 0 2 2 2 0 Fungal protein kinase PBP_GOBP PF01395.22 CEP12223.1 - 0.078 13.1 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 PBP/GOBP family Seadorna_VP7 PF07387.11 CEP12223.1 - 0.082 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 EAP30 PF04157.16 CEP12224.1 - 1.6e-38 132.3 1.4 2.3e-38 131.8 1.4 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CEP12224.1 - 5.8e-24 84.1 0.0 1.3e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 CEP12224.1 - 7e-05 22.1 18.7 0.0013 18.1 6.5 3.4 1 1 1 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 CEP12224.1 - 9.7e-05 21.6 19.4 0.00028 20.1 1.6 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CEP12224.1 - 0.0014 18.6 7.6 0.0043 17.0 7.9 1.7 1 1 1 2 2 2 2 Double zinc ribbon GRAM PF02893.20 CEP12224.1 - 0.015 15.2 0.1 0.085 12.7 0.0 2.4 3 0 0 3 3 3 0 GRAM domain PHD_4 PF16866.5 CEP12224.1 - 0.019 15.0 8.9 0.57 10.3 4.4 3.0 2 1 1 3 3 3 0 PHD-finger zinc_ribbon_15 PF17032.5 CEP12224.1 - 0.12 13.1 5.8 0.22 12.3 5.8 1.4 1 0 0 1 1 1 0 zinc-ribbon family OrfB_Zn_ribbon PF07282.11 CEP12224.1 - 0.48 10.4 9.2 1.1 9.2 1.3 2.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 CEP12224.1 - 2.6 8.1 11.6 2 8.5 1.1 3.2 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Ephrin_rec_like PF07699.13 CEP12224.1 - 9.6 6.1 12.5 3.3 7.5 4.5 2.6 1 1 1 2 2 2 0 Putative ephrin-receptor like HMG_box PF00505.19 CEP12225.1 - 1.4e-20 73.5 2.4 3.1e-20 72.3 2.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP12225.1 - 2.8e-07 31.0 1.3 7.2e-07 29.7 1.3 1.7 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 CEP12225.1 - 0.021 14.2 0.5 0.03 13.6 0.5 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box eRF1_1 PF03463.15 CEP12227.1 - 4.5e-51 172.2 0.1 7.5e-51 171.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CEP12227.1 - 1.4e-29 103.1 0.4 2.3e-29 102.4 0.4 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEP12227.1 - 1.7e-24 86.4 0.0 4.3e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 HTH_57 PF18679.1 CEP12227.1 - 0.066 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain Hexokinase_2 PF03727.16 CEP12229.1 - 3.4e-82 275.5 0.8 4.7e-82 275.0 0.8 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP12229.1 - 1.2e-67 227.7 0.1 1.7e-67 227.2 0.1 1.2 1 0 0 1 1 1 1 Hexokinase DUF1924 PF09086.11 CEP12229.1 - 0.053 13.9 0.0 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) ABC_tran PF00005.27 CEP12230.1 - 4.2e-40 137.4 0.0 1.1e-19 71.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEP12230.1 - 1.1e-12 48.4 8.3 0.0039 17.1 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CEP12230.1 - 7.9e-07 29.4 0.1 0.019 15.2 0.0 3.5 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.6 CEP12230.1 - 9.9e-06 26.2 0.1 0.017 15.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CEP12230.1 - 2e-05 24.2 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CEP12230.1 - 2.5e-05 24.6 0.0 0.098 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEP12230.1 - 2.7e-05 24.0 0.3 2.1 8.1 0.0 3.9 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA PF00004.29 CEP12230.1 - 4.1e-05 24.0 0.2 0.69 10.3 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 CEP12230.1 - 0.00019 20.9 0.3 0.43 10.0 0.1 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CEP12230.1 - 0.0002 21.3 0.0 0.46 10.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 CEP12230.1 - 0.00032 20.9 0.3 1.5 9.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 CEP12230.1 - 0.0004 20.5 0.1 0.023 14.8 0.0 3.1 3 0 0 3 3 3 1 Dynamin family Ploopntkinase1 PF18748.1 CEP12230.1 - 0.00045 19.8 0.0 0.073 12.6 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 AAA_18 PF13238.6 CEP12230.1 - 0.00057 20.4 0.1 3.8 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CEP12230.1 - 0.00059 19.9 0.1 0.98 9.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CEP12230.1 - 0.00061 20.2 0.3 3.1 8.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 CEP12230.1 - 0.0015 18.3 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 CEP12230.1 - 0.0019 17.7 0.0 1.6 8.1 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein cobW PF02492.19 CEP12230.1 - 0.002 17.7 0.1 1.8 8.1 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CEP12230.1 - 0.003 17.3 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 CEP12230.1 - 0.0076 16.2 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CEP12230.1 - 0.0086 16.3 0.0 7.7 6.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CEP12230.1 - 0.0095 16.0 0.0 2.7 8.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CEP12230.1 - 0.01 15.8 0.2 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 NACHT domain T2SSE PF00437.20 CEP12230.1 - 0.011 14.9 0.0 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 CEP12230.1 - 0.011 14.9 0.3 7.6 5.6 0.2 3.2 2 1 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 CEP12230.1 - 0.014 15.9 1.9 3.2 8.2 0.0 3.4 5 0 0 5 5 2 0 AAA domain AAA_PrkA PF08298.11 CEP12230.1 - 0.02 13.8 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain SRPRB PF09439.10 CEP12230.1 - 0.033 13.6 0.4 7.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 CEP12230.1 - 0.037 14.0 1.2 41 4.0 0.0 3.4 3 0 0 3 3 3 0 NTPase dNK PF01712.19 CEP12230.1 - 0.037 13.9 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_25 PF13481.6 CEP12230.1 - 0.038 13.5 0.1 1.9 8.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 CEP12230.1 - 0.04 13.4 0.1 15 5.0 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region Arf PF00025.21 CEP12230.1 - 0.041 13.3 0.0 12 5.4 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.6 CEP12230.1 - 0.042 13.6 0.6 3.8 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CEP12230.1 - 0.046 13.6 0.0 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 CEP12230.1 - 0.053 12.2 0.1 9 4.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CEP12230.1 - 0.085 12.5 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 CEP12230.1 - 0.099 12.4 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 CEP12230.1 - 0.12 11.8 0.0 12 5.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.27 CEP12230.1 - 0.12 11.8 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SbcCD_C PF13558.6 CEP12230.1 - 0.13 12.5 0.0 4.3 7.6 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CEP12230.1 - 0.16 11.7 0.0 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 CEP12230.1 - 0.17 12.0 0.1 5.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Adenylate kinase Mito_carr PF00153.27 CEP12231.1 - 2.4e-55 184.4 0.1 1.5e-18 66.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Choline_transpo PF04515.12 CEP12232.1 - 5.6e-73 246.0 42.3 5.6e-73 246.0 42.3 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 CEP12232.1 - 0.045 14.4 6.0 0.12 13.0 6.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3493 PF11998.8 CEP12232.1 - 1 9.6 0.0 1 9.6 0.0 3.2 2 1 1 3 3 3 0 Low psii accumulation1 / Rep27 Zn_clus PF00172.18 CEP12233.1 - 1e-09 38.4 10.0 1.8e-09 37.6 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE PF01363.21 CEP12234.1 - 2.4e-10 40.4 21.4 6.3e-10 39.0 16.6 3.4 2 1 0 2 2 2 1 FYVE zinc finger MRP-S27 PF10037.9 CEP12234.1 - 0.58 9.0 11.0 0.95 8.3 11.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Hexokinase_2 PF03727.16 CEP12234.1 - 1.9 7.9 5.4 0.3 10.5 0.7 2.0 2 0 0 2 2 2 0 Hexokinase MgsA_C PF12002.8 CEP12234.1 - 3 7.7 6.4 0.24 11.3 0.5 2.2 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal MMS1_N PF10433.9 CEP12236.1 - 3.4e-87 293.1 0.7 6.4e-87 292.2 0.5 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEP12236.1 - 2.7e-57 194.5 0.2 4.4e-56 190.5 0.3 2.7 3 0 0 3 3 3 1 CPSF A subunit region Synaptonemal_3 PF15191.6 CEP12236.1 - 0.15 11.8 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Dus PF01207.17 CEP12237.1 - 1.3e-57 195.2 0.1 2.5e-57 194.3 0.1 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 CEP12237.1 - 0.00036 19.7 0.0 0.0061 15.6 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase DUF1863 PF08937.11 CEP12237.1 - 0.074 13.4 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Nbas_N PF15492.6 CEP12237.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal CHCH PF06747.13 CEP12240.1 - 5.5e-06 26.4 13.2 6.6e-06 26.1 4.5 2.3 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 CEP12240.1 - 2.4e-05 24.3 10.7 0.0009 19.2 3.1 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 CEP12240.1 - 3 8.2 10.1 12 6.2 0.9 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 CEP12240.1 - 4.7 7.3 11.9 8.5 6.5 3.5 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CEP12240.1 - 5.1 6.9 8.6 0.63 9.8 2.2 2.1 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) AAA PF00004.29 CEP12241.1 - 1.6e-43 148.3 0.0 2.7e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP12241.1 - 1.2e-12 47.4 0.1 2.5e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEP12241.1 - 7.8e-12 45.0 0.6 1.3e-11 44.2 0.0 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CEP12241.1 - 6e-07 29.5 0.1 1.7e-05 24.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEP12241.1 - 6.1e-07 29.7 0.0 1.7e-06 28.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CEP12241.1 - 2.7e-06 27.2 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEP12241.1 - 2.7e-06 27.9 0.1 0.0015 18.9 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CEP12241.1 - 0.00013 22.2 0.1 0.0051 17.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP12241.1 - 0.00039 20.0 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 CEP12241.1 - 0.00048 19.4 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CEP12241.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CEP12241.1 - 0.0018 18.8 0.0 0.0048 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 CEP12241.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CEP12241.1 - 0.0025 17.6 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CEP12241.1 - 0.0031 16.8 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 CEP12241.1 - 0.0045 17.0 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 CEP12241.1 - 0.0047 16.5 0.3 0.016 14.9 0.1 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 CEP12241.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CEP12241.1 - 0.007 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CEP12241.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 CEP12241.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEP12241.1 - 0.015 15.0 0.1 0.056 13.2 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CEP12241.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 CEP12241.1 - 0.057 12.8 0.4 0.27 10.5 0.0 2.2 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.17 CEP12241.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CEP12241.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 CEP12241.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP12241.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CEP12241.1 - 0.14 11.4 0.3 0.55 9.5 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CEP12241.1 - 0.15 11.6 0.1 0.39 10.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CEP12241.1 - 0.17 11.6 0.1 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF3967 PF13152.6 CEP12241.1 - 8.1 6.3 6.0 1.5 8.7 0.9 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF3967) NTF2 PF02136.20 CEP12242.1 - 5.2e-08 33.5 0.0 1.4e-06 28.9 0.0 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 CEP12242.1 - 4.6e-06 26.2 0.2 9.8e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 CEP12242.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 CEP12242.1 - 0.013 15.9 4.1 0.037 14.5 1.5 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF2121 PF09894.9 CEP12242.1 - 0.015 14.8 0.8 0.026 14.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) LRR_8 PF13855.6 CEP12242.1 - 0.098 12.4 3.2 0.16 11.8 1.5 2.3 2 1 0 2 2 2 0 Leucine rich repeat Fructosamin_kin PF03881.14 CEP12243.1 - 8.9e-69 231.9 0.0 1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CEP12243.1 - 6.7e-10 39.3 0.0 8.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CEP12243.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-C2H2 PF00096.26 CEP12247.1 - 0.00037 20.8 15.0 0.071 13.6 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP12247.1 - 0.0013 19.1 4.8 0.27 11.7 1.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 CEP12247.1 - 0.0037 17.0 2.9 0.0037 17.0 2.9 2.3 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CEP12247.1 - 0.033 15.0 14.4 0.39 11.7 3.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.9 CEP12247.1 - 0.036 14.1 0.5 9.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.12 CEP12247.1 - 0.055 13.8 10.5 0.11 12.8 10.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CEP12247.1 - 7.5 7.0 12.0 1.6 9.1 1.4 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sugar_tr PF00083.24 CEP12248.1 - 3.9e-109 365.5 20.0 4.8e-71 239.9 3.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP12248.1 - 7.4e-19 67.9 9.3 7.4e-19 67.9 9.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.23 CEP12249.1 - 7.4e-54 182.8 0.1 1.6e-53 181.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 CEP12249.1 - 1.2e-06 28.2 7.5 2.4e-06 27.3 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 CEP12249.1 - 2.1e-06 28.1 0.1 6.4e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 CEP12249.1 - 8.3e-06 25.6 9.6 1.9e-05 24.4 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP12249.1 - 0.00023 21.5 10.7 0.00048 20.4 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEP12249.1 - 0.00023 20.9 10.3 0.0005 19.9 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP12249.1 - 0.0094 15.9 10.1 0.019 15.0 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain UME PF08064.13 CEP12249.1 - 0.077 12.9 0.1 6.1 6.8 0.1 3.6 4 0 0 4 4 4 0 UME (NUC010) domain zf-C3HC4_4 PF15227.6 CEP12249.1 - 0.57 10.4 8.4 1.3 9.2 8.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEP12249.1 - 5.4 7.0 7.8 11 6.0 7.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEP12249.1 - 8.1 6.6 10.3 20 5.3 10.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RicinB_lectin_2 PF14200.6 CEP12250.1 - 5.4e-23 81.5 4.6 4.3e-11 43.4 0.2 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP12250.1 - 5.3e-13 49.3 0.0 1.3e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PAS_7 PF12860.7 CEP12250.1 - 0.06 13.5 0.0 43 4.3 0.0 3.0 3 0 0 3 3 3 0 PAS fold SAM_decarbox PF01536.16 CEP12251.1 - 1.9e-121 405.4 1.6 1.4e-114 382.8 0.6 3.0 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase DHC PF09626.10 CEP12251.1 - 0.071 14.0 0.8 0.16 12.8 0.8 1.6 1 0 0 1 1 1 0 Dihaem cytochrome c DUF211 PF02680.14 CEP12251.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Asp PF00026.23 CEP12253.1 - 8.1e-32 110.9 0.0 7.3e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP12253.1 - 1.7e-06 28.4 0.1 4.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Kelch_5 PF13854.6 CEP12254.1 - 4.4e-11 42.5 2.1 1.2e-06 28.4 0.1 5.3 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 CEP12254.1 - 1.5e-09 37.9 8.6 8.6e-06 25.9 0.1 5.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CEP12254.1 - 2.3e-09 37.1 10.5 0.00058 19.8 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP12254.1 - 3.8e-05 23.5 5.8 0.025 14.6 0.0 5.0 5 0 0 5 5 5 1 Kelch motif ASC PF00858.24 CEP12254.1 - 8.7e-05 21.7 2.4 0.22 10.5 0.1 2.4 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel Kelch_6 PF13964.6 CEP12254.1 - 0.00024 21.3 0.2 0.00024 21.3 0.2 6.4 9 0 0 9 9 9 2 Kelch motif Kelch_1 PF01344.25 CEP12254.1 - 0.0003 20.3 11.2 0.0023 17.5 0.1 4.9 4 1 0 4 4 4 2 Kelch motif ECF_trnsprt PF12822.7 CEP12254.1 - 0.25 11.4 2.8 2.1 8.4 0.4 2.7 3 0 0 3 3 3 0 ECF transporter, substrate-specific component DRIM PF07539.12 CEP12255.1 - 2e-179 597.9 0.4 2e-179 597.9 0.4 4.4 5 1 0 5 5 5 1 Down-regulated in metastasis CLASP_N PF12348.8 CEP12255.1 - 0.0099 15.5 2.2 1 8.9 0.0 4.8 4 1 1 5 5 5 1 CLASP N terminal PPR_2 PF13041.6 CEP12256.1 - 4.4e-29 100.4 19.3 6.2e-12 45.5 0.0 7.7 4 3 4 8 8 8 6 PPR repeat family PPR_3 PF13812.6 CEP12256.1 - 6.5e-26 90.2 14.2 1.4e-09 37.9 0.4 5.8 3 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR PF01535.20 CEP12256.1 - 1.2e-22 78.5 10.6 0.00031 20.8 0.0 7.3 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.7 CEP12256.1 - 4.6e-21 74.2 6.6 0.00013 21.6 0.0 7.4 7 1 1 8 8 8 5 PPR repeat PPR_long PF17177.4 CEP12256.1 - 7.2e-09 35.3 0.1 0.0033 16.8 0.0 3.9 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 CEP12256.1 - 3.7e-05 23.0 2.5 0.44 9.6 0.1 3.3 2 1 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway DUF5591 PF17884.1 CEP12256.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Clr5 PF14420.6 CEP12256.1 - 0.033 14.4 2.9 0.045 14.0 0.1 2.4 2 0 0 2 2 2 0 Clr5 domain MRP-S27 PF10037.9 CEP12256.1 - 0.064 12.1 0.2 2.8 6.7 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_8 PF13181.6 CEP12256.1 - 0.094 13.0 0.7 2.4 8.6 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Phage_ABA_S PF18066.1 CEP12256.1 - 0.14 12.8 1.0 9.8 6.9 0.0 3.4 2 2 1 3 3 3 0 Phage ABA sandwich domain DUF4479 PF14794.6 CEP12256.1 - 0.17 11.8 0.6 1.4 8.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) DUF3367 PF11847.8 CEP12257.1 - 0.0058 14.6 0.1 0.0094 13.9 0.1 1.3 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase DUF1634 PF07843.11 CEP12257.1 - 0.05 13.7 0.4 0.05 13.7 0.4 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) SLATT_5 PF18160.1 CEP12257.1 - 0.062 12.6 0.1 0.062 12.6 0.1 2.1 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DPM3 PF08285.11 CEP12257.1 - 0.47 10.7 5.2 0.41 10.9 2.2 2.5 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) EF-hand_7 PF13499.6 CEP12258.1 - 0.00063 20.1 0.1 0.0015 18.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair F-box PF00646.33 CEP12258.1 - 0.00072 19.4 0.3 0.026 14.4 0.0 2.7 2 0 0 2 2 2 1 F-box domain EF_assoc_1 PF08355.12 CEP12258.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.32 CEP12258.1 - 0.016 14.8 0.6 0.038 13.6 0.6 1.7 1 0 0 1 1 1 0 EF hand Elongin_A PF06881.11 CEP12258.1 - 0.023 15.2 0.1 0.044 14.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 CEP12258.1 - 0.028 14.3 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 F-box-like DUF5024 PF16427.5 CEP12258.1 - 0.059 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) EF-hand_6 PF13405.6 CEP12258.1 - 0.06 13.3 2.5 0.068 13.1 0.6 2.2 2 0 0 2 2 2 0 EF-hand domain Lyase_8 PF02278.18 CEP12259.1 - 4.7e-65 219.6 5.2 9.1e-65 218.7 5.2 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 CEP12259.1 - 2.6e-23 82.4 0.2 4.8e-23 81.6 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 CEP12259.1 - 2.6e-12 47.0 0.5 7.1e-12 45.6 0.5 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Pox_VP8_L4R PF04498.12 CEP12259.1 - 0.036 13.7 0.0 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R LRR_8 PF13855.6 CEP12260.1 - 4.7e-16 58.3 3.9 1.1e-08 34.6 2.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CEP12260.1 - 1.3e-13 50.9 5.1 4.6e-06 26.9 0.3 3.8 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP12260.1 - 2.3e-05 24.3 3.2 5.7 7.9 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 CEP12260.1 - 6.8e-05 22.4 0.6 0.25 10.8 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CEP12260.1 - 0.0026 17.7 4.8 17 5.7 0.3 5.1 5 0 0 5 5 5 1 Leucine Rich repeat Alba PF01918.21 CEP12261.1 - 1.3e-14 53.8 1.3 2.1e-14 53.1 1.3 1.4 1 0 0 1 1 1 1 Alba AA_kinase PF00696.28 CEP12261.1 - 0.092 12.3 0.2 6.1 6.4 0.0 2.1 1 1 1 2 2 2 0 Amino acid kinase family S10_plectin PF03501.15 CEP12262.1 - 1.2e-42 143.9 0.1 1.4e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 CEP12262.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 CEP12262.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DUF4364 PF14277.6 CEP12262.1 - 0.21 11.3 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) Ribosomal_L16 PF00252.18 CEP12263.1 - 1.7e-44 151.0 0.1 2e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Exo_endo_phos PF03372.23 CEP12264.1 - 4e-11 42.9 0.0 5.6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Arrestin_C PF02752.22 CEP12266.1 - 3.3e-09 37.3 10.1 9.8e-06 26.1 0.9 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP12266.1 - 6.9e-08 32.7 0.5 1.7e-05 24.9 0.3 3.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Polyketide_cyc PF03364.20 CEP12267.1 - 5.8e-09 36.3 0.1 6.7e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Proteasome PF00227.26 CEP12268.1 - 7.5e-58 195.1 1.8 5.3e-57 192.4 1.8 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP12268.1 - 6.3e-14 51.3 0.0 1.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HAUS4 PF14735.6 CEP12270.1 - 3.1e-06 27.1 5.7 6.3e-06 26.1 3.1 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 4 WIYLD PF10440.9 CEP12270.1 - 0.031 14.1 0.8 0.056 13.2 0.2 1.7 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1041 PF06292.17 CEP12270.1 - 0.059 13.8 0.8 0.12 12.8 0.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) PX PF00787.24 CEP12271.1 - 2.8e-20 72.4 0.3 3.5e-20 72.1 0.3 1.1 1 0 0 1 1 1 1 PX domain Carb_kinase PF01256.17 CEP12272.1 - 7.5e-50 169.7 0.3 1e-49 169.3 0.3 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CEP12272.1 - 8.5e-10 38.4 0.2 1.5e-09 37.6 0.2 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 CEP12272.1 - 5.2e-05 22.7 0.3 0.00043 19.7 0.3 2.1 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family 7TMR-HDED PF07697.11 CEP12272.1 - 0.028 14.6 0.3 0.039 14.1 0.3 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF5028 PF16431.5 CEP12272.1 - 0.052 13.6 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) Hydrolase_3 PF08282.12 CEP12272.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA_int_endo PF01974.17 CEP12273.1 - 8.6e-18 64.2 0.0 2.2e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SURF1 PF02104.15 CEP12273.1 - 0.048 13.9 0.1 0.057 13.7 0.1 1.3 1 1 0 1 1 1 0 SURF1 family GMP_synt_C PF00958.22 CEP12274.1 - 1.4e-40 137.3 0.1 2.7e-40 136.3 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CEP12274.1 - 1.4e-35 122.8 0.0 2.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CEP12274.1 - 4.6e-09 35.7 0.1 1.1e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CEP12274.1 - 1.2e-08 34.9 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 CEP12274.1 - 0.00047 19.7 0.1 0.039 13.4 0.0 2.8 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CEP12274.1 - 0.00092 18.1 0.1 0.0025 16.7 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CEP12274.1 - 0.0037 16.9 0.1 0.0092 15.6 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 CEP12274.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HOASN PF14515.6 CEP12274.1 - 0.048 14.1 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.20 CEP12274.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family zf-CCHC_2 PF13696.6 CEP12275.1 - 0.0061 16.4 3.8 0.064 13.1 0.1 2.4 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CEP12275.1 - 0.046 13.8 4.5 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 CEP12277.1 - 3e-13 49.8 0.0 6.9e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Endomucin PF07010.12 CEP12279.1 - 7.7 6.4 12.1 10 6.0 12.1 1.1 1 0 0 1 1 1 0 Endomucin Methyltransf_3 PF01596.17 CEP12282.1 - 8.2e-36 123.2 0.1 5.3e-35 120.5 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CEP12282.1 - 6.7e-06 27.1 0.0 3.2e-05 24.9 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 CEP12282.1 - 0.00028 20.7 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CEP12282.1 - 0.0024 17.7 0.1 0.0056 16.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 CEP12283.1 - 4.5e-13 48.9 25.7 2.2e-12 46.6 19.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 CEP12284.1 - 1.4e-43 148.6 7.0 1.7e-43 148.4 7.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP12284.1 - 5.2e-39 134.2 8.5 6.1e-39 134.0 8.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP12284.1 - 6.5e-08 32.7 6.4 5e-07 29.8 6.5 2.2 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CEP12284.1 - 0.0011 18.1 0.5 0.0025 16.9 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CEP12284.1 - 0.044 14.0 0.8 0.097 12.9 0.6 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CEP12284.1 - 0.14 11.6 1.0 0.23 10.9 0.9 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HK PF02110.15 CEP12285.1 - 1.3e-79 267.1 5.3 1.7e-79 266.7 4.3 1.7 1 1 1 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CEP12285.1 - 2.6e-62 209.4 1.0 8.5e-62 207.7 0.2 2.0 2 0 0 2 2 2 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 CEP12285.1 - 1.8e-06 27.6 1.7 3.1e-06 26.9 1.7 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CEP12285.1 - 0.00081 18.8 0.3 0.0015 17.9 0.3 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CPT PF07931.12 CEP12285.1 - 0.037 13.9 0.1 0.46 10.3 0.0 2.5 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Phycobilisome PF00502.19 CEP12285.1 - 0.062 13.2 0.0 0.62 10.0 0.0 2.5 3 0 0 3 3 3 0 Phycobilisome protein GATase_2 PF00310.21 CEP12286.1 - 1.2e-180 600.7 0.0 1.8e-180 600.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CEP12286.1 - 1.2e-153 511.6 0.0 1.9e-153 511.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CEP12286.1 - 2.4e-112 375.0 0.0 5.8e-112 373.7 0.0 1.6 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CEP12286.1 - 8.2e-85 283.2 4.3 1.4e-84 282.4 4.3 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CEP12286.1 - 7.9e-27 94.2 0.1 3.7e-26 92.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CEP12286.1 - 2.3e-23 82.1 0.2 5.1e-23 81.0 0.2 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 CEP12286.1 - 9.8e-08 32.5 0.1 5.7e-05 23.6 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP12286.1 - 1e-07 32.1 0.0 3.1e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEP12286.1 - 8.3e-07 28.5 1.2 0.0099 15.2 0.1 3.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CEP12286.1 - 2.8e-06 26.9 0.6 8.3e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 CEP12286.1 - 3.3e-06 26.9 0.4 0.0014 18.3 0.2 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP12286.1 - 5.7e-05 22.0 1.8 5.7e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CEP12286.1 - 6.4e-05 22.5 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP12286.1 - 0.00039 19.6 0.4 0.0023 17.1 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CEP12286.1 - 0.0016 18.8 0.0 1.8 9.0 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CEP12286.1 - 0.004 16.4 0.1 0.031 13.5 0.1 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 CEP12286.1 - 0.0041 16.3 0.1 0.037 13.1 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CEP12286.1 - 0.0048 16.2 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 CEP12286.1 - 0.018 14.4 0.1 0.46 9.8 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GATase_6 PF13522.6 CEP12286.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMO-like PF00743.19 CEP12286.1 - 0.062 11.7 0.3 0.29 9.5 0.0 2.2 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 CEP12286.1 - 0.076 13.0 1.0 0.16 12.0 0.0 2.1 3 0 0 3 3 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 CEP12286.1 - 0.11 12.6 0.0 51 3.9 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.18 CEP12286.1 - 0.19 10.8 0.4 0.98 8.4 0.6 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase IlvN PF07991.12 CEP12286.1 - 0.45 10.1 1.6 1.2 8.7 0.1 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain IPPT PF01715.17 CEP12287.1 - 2.9e-67 226.8 0.1 4.4e-67 226.2 0.1 1.2 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 CEP12287.1 - 0.00026 21.2 0.1 0.0016 18.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain IPT PF01745.16 CEP12287.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase PRK PF00485.18 CEP12287.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CEP12287.1 - 0.028 14.8 0.1 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CEP12287.1 - 0.029 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 CEP12287.1 - 0.042 13.4 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 CEP12287.1 - 0.14 12.1 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase CbiA PF01656.23 CEP12287.1 - 0.27 11.3 0.6 0.56 10.3 0.5 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 CEP12287.1 - 2.4 8.7 4.8 1.1 9.8 0.8 2.5 2 2 0 2 2 2 0 ABC transporter HSF_DNA-bind PF00447.17 CEP12288.1 - 3.7e-29 101.2 0.2 1.5e-28 99.3 0.2 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Cse1 PF08506.10 CEP12288.1 - 0.038 12.8 0.1 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 Cse1 TMEM52 PF14979.6 CEP12288.1 - 0.14 12.1 1.7 0.63 9.9 1.7 2.1 1 0 0 1 1 1 0 Transmembrane 52 DUF4058 PF13267.6 CEP12288.1 - 1.7 8.0 5.5 5 6.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4058) MFS_1 PF07690.16 CEP12289.1 - 2.6e-35 122.0 16.8 2.6e-35 122.0 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily KOG2701 PF09762.9 CEP12289.1 - 0.091 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) SKN1 PF03935.15 CEP12289.1 - 0.2 10.0 0.2 0.38 9.1 0.2 1.4 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) SH3_1 PF00018.28 CEP12290.1 - 1.6e-13 50.0 0.1 2.6e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP12290.1 - 6.4e-10 38.7 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP12290.1 - 1.8e-09 37.1 0.0 3.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP12290.1 - 0.004 17.4 0.1 0.0068 16.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 CEP12290.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.6 2 0 0 2 2 2 0 SH3 domain TMEMspv1-c74-12 PF11044.8 CEP12290.1 - 0.47 10.5 7.4 0.44 10.6 4.3 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Copper-fist PF00649.18 CEP12291.1 - 2.4e-17 62.1 4.4 7.2e-17 60.6 4.4 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain CN_hydrolase PF00795.22 CEP12292.1 - 2.9e-57 194.0 0.0 3.2e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF963 PF06131.11 CEP12293.1 - 0.045 13.2 4.1 0.11 11.9 0.5 2.2 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ferric_reduct PF01794.19 CEP12294.1 - 1.2e-17 64.2 8.0 1.2e-17 64.2 8.0 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEP12294.1 - 4.7e-08 33.3 0.0 7.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEP12294.1 - 1.3e-07 31.7 0.4 2.3e-06 27.6 0.4 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CEP12294.1 - 0.0012 19.5 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Methyltr_RsmB-F PF01189.17 CEP12295.1 - 1.7e-31 109.4 0.0 1.2e-30 106.6 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CEP12295.1 - 0.0012 19.5 0.0 0.0053 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP12295.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CEP12295.1 - 0.038 14.1 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CEP12295.1 - 0.045 13.5 0.9 0.6 9.9 0.0 2.6 2 2 1 3 3 3 0 Methyltransferase domain RTC PF01137.21 CEP12295.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase MIP PF00230.20 CEP12296.1 - 2.6e-50 171.3 10.2 3.2e-50 171.0 10.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein WW PF00397.26 CEP12297.1 - 1.2e-12 47.7 3.3 3.2e-12 46.3 3.3 1.8 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 CEP12297.1 - 1.5e-05 25.2 6.2 1.7e-05 25.0 6.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ABA_WDS PF02496.16 CEP12297.1 - 0.0045 17.4 0.3 0.0085 16.5 0.3 1.4 1 0 0 1 1 1 1 ABA/WDS induced protein SAP18 PF06487.12 CEP12300.1 - 0.052 13.7 0.8 0.13 12.4 0.8 1.7 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) BIRC6 PF12356.8 CEP12300.1 - 0.11 11.9 2.7 0.12 11.8 0.2 2.0 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 WD40 PF00400.32 CEP12301.1 - 2.3e-15 56.7 17.4 0.0033 18.2 0.0 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12301.1 - 0.0054 17.0 0.3 1.3 9.4 0.0 3.8 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CAP_N PF01213.19 CEP12301.1 - 0.079 12.4 3.5 0.14 11.6 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CEP12301.1 - 0.52 10.4 3.7 1.7 8.7 3.7 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TFIIE_alpha PF02002.17 CEP12302.1 - 2.1e-15 56.4 0.1 4.8e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit B-block_TFIIIC PF04182.12 CEP12302.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.8 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC HypA PF01155.19 CEP12302.1 - 0.069 13.2 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MarR_2 PF12802.7 CEP12302.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family TF_Zn_Ribbon PF08271.12 CEP12302.1 - 0.65 9.6 5.6 3.7 7.1 5.0 2.5 1 1 1 2 2 2 0 TFIIB zinc-binding TFIIA PF03153.13 CEP12303.1 - 0.049 13.6 19.7 0.013 15.5 16.8 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 CEP12304.1 - 9.1e-47 157.0 9.6 3.6e-17 62.3 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP12304.1 - 1.7e-37 127.4 7.6 3.3e-17 62.5 0.2 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain zf-C2H2 PF00096.26 CEP12304.1 - 8.3e-06 26.0 7.1 0.12 12.8 0.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP12304.1 - 0.0024 18.6 7.4 1.4 9.9 0.1 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger SANT_DAMP1_like PF16282.5 CEP12304.1 - 0.0053 16.9 0.6 4.6 7.5 0.0 2.9 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 CEP12304.1 - 0.014 15.4 8.9 0.29 11.2 1.1 3.8 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_aberr PF17017.5 CEP12304.1 - 0.016 15.3 7.2 2 8.6 0.5 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 CEP12304.1 - 0.047 14.0 0.0 0.047 14.0 0.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc ribbon NUC194 PF08163.12 CEP12304.1 - 2.3 7.1 6.8 4.2 6.2 6.8 1.3 1 0 0 1 1 1 0 NUC194 domain VRR_NUC PF08774.11 CEP12306.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain Plant_tran PF04827.14 CEP12308.1 - 1.2e-24 87.1 0.2 2.3e-24 86.2 0.2 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 CEP12308.1 - 8.5e-06 25.5 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Spore_III_AF PF09581.10 CEP12308.1 - 0.15 12.1 7.6 0.23 11.5 7.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TP53IP5 PF15331.6 CEP12308.1 - 9.9 6.2 7.9 2.8 8.0 4.7 1.6 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 NAM-associated PF14303.6 CEP12309.1 - 9.1e-10 39.5 0.9 2e-09 38.4 0.9 1.5 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Myb_DNA-bind_4 PF13837.6 CEP12309.1 - 0.0015 18.9 0.2 0.0015 18.9 0.2 2.6 2 1 1 3 3 3 1 Myb/SANT-like DNA-binding domain Plant_tran PF04827.14 CEP12310.1 - 1.5e-76 256.6 0.1 2.4e-40 138.3 0.0 3.0 2 1 1 3 3 3 2 Plant transposon protein DDE_Tnp_4 PF13359.6 CEP12310.1 - 1.7e-09 37.5 0.0 1.6e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 CEP12310.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain AsnC_trans_reg PF01037.21 CEP12310.1 - 0.15 12.1 0.3 3.5 7.6 0.0 2.7 2 1 1 3 3 3 0 Lrp/AsnC ligand binding domain Rap1a PF18602.1 CEP12311.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Rap1a immunity proteins PIF1 PF05970.14 CEP12313.1 - 3.4e-17 62.7 9.5 1.6e-08 34.1 2.4 4.0 1 1 2 3 3 3 3 PIF1-like helicase SH3_13 PF18335.1 CEP12313.1 - 0.046 13.5 2.1 0.41 10.5 0.1 3.2 3 1 0 3 3 3 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA_30 PF13604.6 CEP12313.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 CEP12314.1 - 0.006 16.6 1.3 0.006 16.6 1.3 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 CEP12314.1 - 0.023 14.4 1.2 0.061 13.1 1.2 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP12314.1 - 0.089 12.6 0.8 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 CEP12316.1 - 1.7e-10 40.8 0.1 5.1e-10 39.2 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP12319.1 - 1.5e-09 38.1 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP12319.1 - 2.3e-06 27.6 0.7 3.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain IreB PF06135.12 CEP12319.1 - 0.088 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 IreB regulatory phosphoprotein rve PF00665.26 CEP12320.1 - 3.4e-13 49.8 0.0 8.9e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 CEP12320.1 - 1.3e-09 37.8 1.0 1.3e-09 37.8 1.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.6 CEP12322.1 - 1.9e-09 37.4 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 CEP12322.1 - 4.6e-05 23.3 0.2 0.00012 22.0 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CEP12322.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 CEP12322.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 CEP12322.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 CEP12322.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 MarR family AAA_30 PF13604.6 CEP12324.1 - 0.00011 22.0 0.0 0.0003 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP12324.1 - 0.0012 19.1 1.6 0.017 15.4 0.0 3.1 4 0 0 4 4 4 1 AAA domain TsaE PF02367.17 CEP12324.1 - 0.0016 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CEP12324.1 - 0.023 15.0 0.0 4.4 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain TK PF00265.18 CEP12324.1 - 0.033 14.1 0.2 0.98 9.3 0.0 2.6 2 0 0 2 2 2 0 Thymidine kinase AAA PF00004.29 CEP12324.1 - 0.14 12.6 0.0 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CEP12324.1 - 0.58 10.1 3.2 1.3 9.0 0.5 2.9 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit Pirin PF02678.16 CEP12325.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Pirin PIF1 PF05970.14 CEP12326.1 - 1.6e-26 93.4 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP12326.1 - 5.7e-05 21.3 0.0 8.1e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP12326.1 - 0.003 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain FixQ PF05545.11 CEP12327.1 - 0.51 10.4 1.9 1.1 9.3 1.9 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PMR5N PF14416.6 CEP12328.1 - 0.0012 19.2 0.0 68 3.9 0.0 4.7 4 1 1 5 5 5 0 PMR5 N terminal Domain DUF5465 PF17553.2 CEP12328.1 - 0.024 15.0 11.8 8.7 7.2 0.2 5.0 5 0 0 5 5 5 0 Family of unknown function (DUF5465) Nup_retrotrp_bd PF10599.9 CEP12328.1 - 3.8 8.2 9.5 7.6 7.3 9.5 1.8 1 1 0 1 1 1 0 Retro-transposon transporting motif AAA_22 PF13401.6 CEP12331.1 - 1.1e-05 25.8 0.1 0.0032 17.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CEP12331.1 - 0.0003 20.8 0.6 0.58 10.2 0.0 4.5 4 1 0 4 4 4 1 AAA domain TsaE PF02367.17 CEP12331.1 - 0.0003 20.8 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CEP12331.1 - 0.00062 20.1 3.7 0.23 11.8 2.3 3.0 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEP12331.1 - 0.0046 17.1 0.6 2.4 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain TK PF00265.18 CEP12331.1 - 0.018 14.9 0.1 2.8 7.8 0.0 2.9 3 0 0 3 3 3 0 Thymidine kinase AAA PF00004.29 CEP12331.1 - 0.026 14.9 0.1 0.21 12.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEP12331.1 - 0.053 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 CEP12331.1 - 0.06 12.7 0.2 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 ThiF family ResIII PF04851.15 CEP12331.1 - 0.065 13.2 0.0 0.32 11.0 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Exo_endo_phos PF03372.23 CEP12332.1 - 0.008 15.7 0.0 0.031 13.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YfhO PF09586.10 CEP12334.1 - 0.27 9.4 0.5 0.27 9.4 0.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO NDC10_II PF16787.5 CEP12336.1 - 4.4e-06 26.0 0.0 6.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 zf-CCHC PF00098.23 CEP12339.1 - 0.13 12.3 13.9 0.093 12.9 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Aminotran_5 PF00266.19 CEP12341.1 - 3.8e-51 174.2 0.0 4.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_18 PF00704.28 CEP12344.1 - 3.7e-21 76.2 0.4 3e-20 73.2 0.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1688 PF07958.11 CEP12345.1 - 3.6e-154 513.5 0.0 5.5e-154 512.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) HA2 PF04408.23 CEP12345.1 - 1.8e-25 89.3 0.0 1.8e-25 89.3 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEP12345.1 - 3.4e-15 56.2 0.0 7.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEP12345.1 - 1.5e-11 44.6 0.0 3e-10 40.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP12345.1 - 4.1e-09 36.4 0.3 9.5e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP12345.1 - 2.9e-07 30.8 0.1 2.8e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEP12345.1 - 0.0026 18.1 0.1 0.0066 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP12345.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEP12345.1 - 0.0075 15.4 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 CEP12345.1 - 0.0075 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 CEP12345.1 - 0.0081 16.2 0.3 0.078 13.0 0.3 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CEP12345.1 - 0.032 14.4 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEP12345.1 - 0.037 13.3 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEP12345.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 CEP12345.1 - 0.11 13.1 0.1 1.2 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CEP12345.1 - 0.16 12.5 0.0 0.16 12.5 0.0 3.3 3 1 0 3 3 2 0 AAA domain Cytokin_check_N PF10407.9 CEP12345.1 - 0.25 11.3 1.3 80 3.3 0.0 3.9 4 0 0 4 4 4 0 Cdc14 phosphatase binding protein N-terminus DUF4692 PF15763.5 CEP12345.1 - 0.37 11.2 2.5 1.2 9.6 2.5 1.8 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) NUC205 PF08168.11 CEP12346.1 - 0.019 14.4 0.1 2.6 7.6 0.0 2.7 2 0 0 2 2 2 0 NUC205 domain FAR1 PF03101.15 CEP12346.1 - 0.06 14.0 0.5 0.06 14.0 0.5 1.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain RRM_1 PF00076.22 CEP12347.1 - 0.03 14.1 0.0 0.53 10.2 0.0 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhomboid PF01694.22 CEP12348.1 - 1.4e-22 80.3 8.7 2.6e-22 79.4 8.7 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 CEP12348.1 - 0.012 16.1 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) TP2 PF01254.18 CEP12349.1 - 0.14 12.8 10.2 0.32 11.6 10.2 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 Glyco_hydro81C PF17652.1 CEP12350.1 - 1.5e-94 317.1 4.4 1.7e-93 313.6 2.6 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CEP12350.1 - 5.6e-52 176.9 0.0 8.2e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Methyltransf_11 PF08241.12 CEP12351.1 - 2.3e-14 53.8 0.0 7.1e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12351.1 - 2.1e-12 47.2 0.0 3.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP12351.1 - 8.5e-12 45.6 0.1 2.3e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP12351.1 - 7.8e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12351.1 - 3.7e-07 30.8 0.0 9.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP12351.1 - 3.1e-06 26.7 0.2 4.4e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CEP12351.1 - 0.0019 18.0 0.1 0.0054 16.5 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEP12351.1 - 0.023 14.3 0.3 0.041 13.4 0.3 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 CEP12351.1 - 0.041 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_PK PF05891.12 CEP12351.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_7 PF03492.15 CEP12351.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase B5 PF03484.15 CEP12351.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetase B5 domain FlxA PF14282.6 CEP12352.1 - 4.8 7.2 8.7 0.24 11.4 3.0 1.6 2 0 0 2 2 2 0 FlxA-like protein RVT_1 PF00078.27 CEP12353.1 - 5.4e-13 49.0 0.1 7.9e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SAM_2 PF07647.17 CEP12356.1 - 1.8e-07 31.2 0.5 3.9e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP12356.1 - 1.1e-05 25.8 0.7 4.3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase PF00069.25 CEP12357.1 - 6.9e-53 179.7 0.5 1.2e-51 175.6 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 CEP12357.1 - 7.7e-37 124.7 17.5 6.9e-07 29.9 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 CEP12357.1 - 3.4e-20 72.4 0.0 8.8e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase F-box PF00646.33 CEP12357.1 - 2.3e-08 33.7 0.1 4.8e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP12357.1 - 2.5e-08 33.7 0.2 5e-08 32.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like APH PF01636.23 CEP12357.1 - 2.7e-06 27.5 0.0 0.00027 21.0 0.2 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Nup160 PF11715.8 CEP12357.1 - 0.00048 18.9 3.2 1.7 7.2 0.0 4.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEP12357.1 - 0.00061 20.0 1.7 0.7 10.2 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP12357.1 - 0.0057 16.0 0.4 0.68 9.2 0.1 2.5 2 1 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 CEP12357.1 - 0.0075 16.1 0.5 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 F-box Pkinase_fungal PF17667.1 CEP12357.1 - 0.0084 14.9 0.1 0.032 13.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PALB2_WD40 PF16756.5 CEP12357.1 - 0.015 14.2 1.1 0.41 9.5 0.0 3.2 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Choline_kinase PF01633.20 CEP12357.1 - 0.042 13.4 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2459 PF09601.10 CEP12357.1 - 0.079 12.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) PRANC PF09372.10 CEP12357.1 - 0.12 12.7 0.6 0.78 10.1 0.1 2.6 2 0 0 2 2 2 0 PRANC domain zf-C2H2_6 PF13912.6 CEP12361.1 - 0.0091 16.0 0.3 0.02 14.9 0.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CEP12361.1 - 0.27 12.2 2.0 0.31 12.0 0.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger GCR1_C PF12550.8 CEP12362.1 - 0.00014 22.1 0.2 0.00062 20.0 0.2 2.0 1 1 1 2 2 2 1 Transcriptional activator of glycolytic enzymes zf_CCCH_5 PF18384.1 CEP12362.1 - 0.099 12.8 1.5 0.19 11.9 1.5 1.4 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) NDC10_II PF16787.5 CEP12362.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GTP_EFTU PF00009.27 CEP12363.1 - 5.4e-17 62.0 0.0 9.8e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP12363.1 - 0.00037 20.4 0.2 0.097 12.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CEP12363.1 - 0.0014 19.2 0.1 0.0096 16.4 0.0 2.2 1 1 1 2 2 2 1 ABC transporter ATP_bind_1 PF03029.17 CEP12363.1 - 0.016 15.0 0.6 0.69 9.6 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 CEP12363.1 - 0.02 14.5 0.2 0.25 10.9 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CEP12363.1 - 0.029 14.4 0.1 0.17 12.0 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 CEP12363.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CEP12363.1 - 0.071 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CEP12363.1 - 0.11 11.9 0.1 5 6.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3759 PF12585.8 CEP12364.1 - 1.1e-19 70.2 8.9 1.1e-19 70.2 8.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 CEP12364.1 - 0.00038 21.1 0.0 0.77 10.5 0.0 3.2 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like SMC_N PF02463.19 CEP12365.1 - 8.1e-66 221.6 9.2 2.5e-65 220.0 9.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEP12365.1 - 1.8e-27 95.9 0.4 6.5e-26 90.9 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CEP12365.1 - 1.7e-13 51.6 32.2 1.7e-13 51.6 32.2 6.3 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 CEP12365.1 - 1.2e-10 41.7 23.9 3e-07 30.5 0.5 4.4 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CEP12365.1 - 4.7e-10 39.7 34.5 1.5e-09 38.0 16.8 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 CEP12365.1 - 0.011 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiS PF02597.20 CEP12365.1 - 1.1 9.9 7.1 1.4 9.6 0.0 4.1 3 0 0 3 3 3 0 ThiS family Matrilin_ccoil PF10393.9 CEP12365.1 - 2.8 7.9 9.1 4.3 7.3 0.1 4.7 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Septin PF00735.18 CEP12366.1 - 3.1e-18 66.1 2.0 5.5e-18 65.2 0.0 2.4 2 1 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 CEP12366.1 - 3.6e-05 23.7 0.1 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP12366.1 - 0.0038 17.3 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CEP12366.1 - 0.021 15.0 1.9 0.044 14.0 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CEP12366.1 - 0.033 13.9 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 CEP12366.1 - 0.04 14.3 0.2 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CEP12366.1 - 0.055 13.7 2.6 0.097 12.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain AIM5 PF17050.5 CEP12366.1 - 0.071 13.9 1.3 0.28 12.0 0.0 2.8 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 KCNQC3-Ank-G_bd PF11956.8 CEP12366.1 - 0.084 13.2 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 AAA PF00004.29 CEP12366.1 - 0.089 13.2 3.9 1.4 9.3 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HIN PF02760.15 CEP12366.1 - 0.1 12.3 3.5 0.074 12.8 1.3 1.9 2 0 0 2 2 2 0 HIN-200/IF120x domain Rdx PF10262.9 CEP12367.1 - 7.6e-30 102.9 0.0 1.1e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family TPR_12 PF13424.6 CEP12368.1 - 2.3e-17 63.1 8.0 5.8e-06 26.5 0.8 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12368.1 - 7e-14 51.0 9.1 0.089 12.6 2.5 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12368.1 - 1.6e-13 49.6 11.1 0.11 12.6 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP12368.1 - 5.5e-09 35.5 10.3 0.67 10.3 1.3 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEP12368.1 - 5.9e-07 29.2 5.9 0.045 13.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP12368.1 - 0.0021 18.0 9.5 3.4 7.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12368.1 - 0.0033 17.7 0.4 0.098 13.1 0.2 3.4 4 1 0 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 CEP12368.1 - 0.0039 17.8 2.7 22 5.9 0.1 4.7 4 0 0 4 4 4 0 Sel1 repeat TPR_MalT PF17874.1 CEP12368.1 - 0.004 16.6 0.8 0.32 10.3 0.1 2.8 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 CEP12368.1 - 0.031 15.1 7.0 18 6.5 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEP12368.1 - 0.044 14.3 4.2 3.3 8.3 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3094 PF11293.8 CEP12368.1 - 0.049 13.4 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TPR_16 PF13432.6 CEP12368.1 - 0.061 14.0 5.2 3.1 8.5 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 CEP12368.1 - 0.073 12.5 0.6 25 4.3 0.0 3.2 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF2989 PF11207.8 CEP12368.1 - 0.11 12.2 0.1 0.96 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) PPR PF01535.20 CEP12368.1 - 0.15 12.4 0.3 34 5.0 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 CEP12368.1 - 0.56 11.0 5.7 90 4.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1240 PF06836.12 CEP12369.1 - 1.1 9.9 7.2 2.9 8.5 7.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) OPT PF03169.15 CEP12370.1 - 3.7e-91 306.6 35.6 4.2e-91 306.5 35.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 CEP12370.1 - 0.021 15.1 0.3 0.079 13.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Halogen_Hydrol PF10112.9 CEP12370.1 - 1.9 8.4 3.6 1.9 8.5 0.6 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SPC25 PF06703.11 CEP12371.1 - 8.4e-44 149.2 2.1 9.6e-44 149.0 2.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pyr_redox_2 PF07992.14 CEP12372.1 - 8.1e-65 218.9 6.0 1.3e-64 218.3 6.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEP12372.1 - 4.2e-32 110.7 2.2 3.4e-31 107.8 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEP12372.1 - 1.6e-18 67.1 0.3 1.6e-18 67.1 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP12372.1 - 4.1e-13 49.3 0.5 4.1e-13 49.3 0.5 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP12372.1 - 4.9e-06 26.2 4.1 1.2e-05 24.9 4.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CEP12372.1 - 1.9e-05 24.1 0.1 0.00032 20.1 0.1 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CEP12372.1 - 4.9e-05 22.2 12.6 0.1 11.3 0.1 3.5 3 1 1 4 4 4 3 HI0933-like protein 3HCDH_N PF02737.18 CEP12372.1 - 0.00011 22.2 0.2 0.00011 22.2 0.2 2.4 2 1 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEP12372.1 - 0.00059 19.2 4.8 0.006 15.9 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CEP12372.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 CEP12372.1 - 0.0014 17.8 0.1 0.012 14.8 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEP12372.1 - 0.0029 17.8 2.2 0.0029 17.8 2.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CEP12372.1 - 0.0063 15.6 12.4 0.054 12.6 6.5 3.0 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CEP12372.1 - 0.0089 15.1 4.4 0.12 11.5 2.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A MCRA PF06100.11 CEP12372.1 - 0.017 13.9 0.5 2.1 7.0 0.2 2.1 2 0 0 2 2 2 0 MCRA family Thi4 PF01946.17 CEP12372.1 - 0.086 12.1 8.1 0.26 10.5 5.2 2.8 2 1 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 CEP12372.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.9 2 1 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 CEP12372.1 - 0.24 11.9 2.0 0.52 10.8 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CEP12372.1 - 0.38 11.3 0.0 0.38 11.3 0.0 2.1 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 CEP12372.1 - 0.63 9.6 18.2 0.77 9.3 0.1 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEP12372.1 - 6.8 5.8 8.4 0.56 9.4 0.3 2.6 2 1 0 2 2 2 0 FAD binding domain FAA_hydrolase PF01557.18 CEP12373.1 - 3.7e-54 183.7 0.0 4.3e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HMG_box PF00505.19 CEP12374.1 - 2.4e-33 114.3 15.8 3.4e-15 56.2 0.1 4.6 4 1 0 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP12374.1 - 3e-29 101.4 14.5 1.1e-13 51.5 0.5 4.7 5 0 0 5 5 5 3 HMG-box domain Protamine_like PF06382.11 CEP12374.1 - 1.8 8.7 7.4 0.23 11.6 0.4 2.8 2 1 1 3 3 3 0 Protamine and protamine like Methyltransf_16 PF10294.9 CEP12375.1 - 7.5e-34 117.0 0.0 1.5e-33 116.0 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CEP12375.1 - 0.0054 16.5 0.1 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP12375.1 - 0.0071 17.0 0.1 0.022 15.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12375.1 - 0.0097 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12375.1 - 0.039 14.7 0.0 0.11 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 CEP12375.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.5 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase cNMP_binding PF00027.29 CEP12376.1 - 1.4e-39 134.0 0.5 1.5e-19 69.8 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CEP12376.1 - 3.3e-08 33.1 1.6 6.7e-08 32.1 1.6 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CEP12376.1 - 0.023 14.4 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif Septin PF00735.18 CEP12377.1 - 1.2e-109 365.9 0.4 2.1e-109 365.2 0.4 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP12377.1 - 4.9e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP12377.1 - 5e-07 29.5 3.4 1.9e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP12377.1 - 2.9e-06 27.3 0.2 2.9e-06 27.3 0.2 2.7 3 1 1 4 4 4 1 RsgA GTPase Roc PF08477.13 CEP12377.1 - 0.00012 22.3 0.1 0.00029 21.0 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 CEP12377.1 - 0.0028 17.3 0.1 0.012 15.2 0.1 1.9 1 1 0 1 1 1 1 Exonuclease VII, large subunit Ras PF00071.22 CEP12377.1 - 0.0057 16.3 0.2 0.016 14.8 0.2 1.8 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.6 CEP12377.1 - 0.0059 16.9 1.7 0.0064 16.8 0.2 1.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CEP12377.1 - 0.0061 17.0 0.8 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CEP12377.1 - 0.0069 16.8 0.0 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AIG1 PF04548.16 CEP12377.1 - 0.0072 15.7 0.1 0.021 14.2 0.1 1.8 1 0 0 1 1 1 1 AIG1 family Sigma54_activat PF00158.26 CEP12377.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 CEP12377.1 - 0.012 14.9 1.4 0.013 14.9 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 CEP12377.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 CEP12377.1 - 0.019 14.5 0.3 0.04 13.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CEP12377.1 - 0.03 14.4 7.6 2.6 8.1 0.1 3.4 2 1 1 3 3 3 0 Dynamin family AAA_24 PF13479.6 CEP12377.1 - 0.056 13.1 0.4 0.056 13.1 0.4 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEP12377.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP12377.1 - 0.098 12.8 0.2 0.098 12.8 0.2 2.0 2 1 0 2 2 2 0 AAA domain SecB PF02556.14 CEP12377.1 - 0.13 12.1 1.3 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit SecB ABC_tran PF00005.27 CEP12377.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.3 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 CEP12377.1 - 2.7 7.7 5.8 1.4 8.7 0.1 2.9 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Leu_zip PF15294.6 CEP12378.1 - 0.00095 18.8 11.0 0.002 17.7 11.0 1.5 1 0 0 1 1 1 1 Leucine zipper zf-C3HC4_3 PF13920.6 CEP12378.1 - 0.0021 17.9 17.2 0.11 12.4 4.7 3.0 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Spc24 PF08286.11 CEP12378.1 - 0.027 14.7 8.7 0.069 13.4 8.7 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CEP12378.1 - 0.034 14.7 7.8 0.068 13.7 7.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region HALZ PF02183.18 CEP12378.1 - 0.06 13.6 11.7 0.12 12.6 0.4 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 CEP12378.1 - 0.088 12.9 7.7 0.22 11.6 7.7 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 CEP12378.1 - 0.15 12.9 9.5 0.42 11.5 9.5 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 CEP12378.1 - 0.22 11.6 13.6 0.89 9.6 12.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 CEP12378.1 - 0.31 10.9 7.8 0.62 9.9 7.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) KASH_CCD PF14662.6 CEP12378.1 - 0.59 9.9 16.3 1.1 9.0 16.3 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 CEP12378.1 - 0.81 10.1 9.2 1.5 9.2 9.2 1.3 1 0 0 1 1 1 0 Fez1 FapA PF03961.13 CEP12378.1 - 1.2 7.7 5.4 1.9 7.0 5.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A VEK-30 PF12107.8 CEP12378.1 - 1.2 9.1 3.2 2.5 8.1 1.4 2.5 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway DivIC PF04977.15 CEP12378.1 - 2.1 8.2 10.6 0.73 9.7 1.6 3.1 1 1 2 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 CEP12378.1 - 3.2 8.2 8.3 0.92 10.0 0.3 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) PSS PF03034.15 CEP12379.1 - 1.9e-113 378.8 16.4 1.9e-113 378.8 16.4 1.5 2 0 0 2 2 2 1 Phosphatidyl serine synthase Glycoprotein PF03409.15 CEP12379.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein DUF1772 PF08592.11 CEP12379.1 - 0.45 10.8 4.5 2.3 8.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) SAC3_GANP PF03399.16 CEP12380.1 - 2.5e-13 50.1 5.2 3.6e-11 43.0 5.2 2.1 1 1 0 1 1 1 1 SAC3/GANP family TPR_MalT PF17874.1 CEP12380.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region MCM_lid PF17855.1 CEP12380.1 - 0.083 13.3 0.6 15 6.0 0.0 2.7 2 1 0 2 2 2 0 MCM AAA-lid domain DUF2829 PF11195.8 CEP12380.1 - 0.093 13.0 0.4 0.55 10.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) Ribosomal_S26e PF01283.19 CEP12381.1 - 5e-54 181.3 7.5 5.9e-54 181.1 7.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e GWT1 PF06423.12 CEP12382.1 - 0.41 10.8 3.2 0.58 10.3 3.2 1.3 1 1 0 1 1 1 0 GWT1 Imm5 PF14423.6 CEP12384.1 - 1.1 9.5 5.3 3.1 8.0 0.0 2.7 3 1 0 3 3 3 0 Immunity protein Imm5 PIF1 PF05970.14 CEP12386.1 - 7.2e-40 137.3 0.0 1e-39 136.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP12386.1 - 1.3e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP12386.1 - 6.1e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP12386.1 - 0.0031 17.9 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP12386.1 - 0.0041 17.4 0.3 0.036 14.3 0.0 2.4 1 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 CEP12386.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 CEP12386.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CEP12386.1 - 0.039 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEP12386.1 - 0.041 13.1 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 CEP12386.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein T2SSE PF00437.20 CEP12386.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CEP12386.1 - 0.15 12.1 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CEP12386.1 - 0.15 11.7 0.3 0.34 10.6 0.0 1.8 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Peptidase_M1 PF01433.20 CEP12387.1 - 2.7e-46 157.9 0.0 4.1e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CEP12387.1 - 6.3e-39 132.6 0.1 1.2e-38 131.7 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CEP12387.1 - 4.8e-26 92.1 0.0 7.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain FlaC_arch PF05377.11 CEP12388.1 - 0.00059 20.2 1.8 0.00059 20.2 1.8 2.7 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CEP12388.1 - 0.02 15.0 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 CEP12388.1 - 0.02 15.4 0.2 1.3 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF632 PF04782.12 CEP12388.1 - 0.029 13.7 0.5 0.044 13.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF632) THOC7 PF05615.13 CEP12388.1 - 0.036 14.3 0.2 0.089 13.1 0.2 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 Sec34 PF04136.15 CEP12388.1 - 0.082 12.8 1.1 3 7.7 1.0 2.5 2 1 0 2 2 2 0 Sec34-like family BORCS7 PF16088.5 CEP12388.1 - 0.084 13.1 5.7 2.1 8.7 3.3 2.8 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 NPV_P10 PF05531.12 CEP12388.1 - 0.09 13.3 0.7 0.77 10.3 0.5 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 CEP12388.1 - 0.11 12.5 2.3 0.38 10.8 0.8 2.2 2 0 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 CEP12388.1 - 0.11 12.6 1.7 0.18 12.0 0.7 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 CEP12388.1 - 0.16 11.9 3.1 0.18 11.8 0.3 2.4 3 0 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 CEP12388.1 - 0.23 11.5 2.2 0.28 11.2 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 CEP12388.1 - 0.28 11.3 2.2 2.9 8.1 0.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor zf-C3HC4 PF00097.25 CEP12390.1 - 9.4e-11 41.4 7.9 1.6e-10 40.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP12390.1 - 2.3e-09 37.4 9.4 4.9e-09 36.4 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP12390.1 - 1.1e-08 34.8 8.9 1.9e-08 34.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP12390.1 - 2.4e-08 33.7 7.8 3.7e-08 33.1 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP12390.1 - 2.7e-08 33.7 7.3 8.9e-08 32.0 7.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP12390.1 - 8.4e-08 32.0 6.8 1.5e-07 31.2 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 CEP12390.1 - 1.5e-05 25.0 4.4 2.2e-05 24.4 4.4 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CEP12390.1 - 2.1e-05 24.3 9.4 3.6e-05 23.5 9.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEP12390.1 - 2.3e-05 24.4 8.3 4e-05 23.7 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CEP12390.1 - 8.9e-05 22.5 3.4 0.0012 18.9 4.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEP12390.1 - 0.00028 21.1 7.3 0.00028 21.1 7.3 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CEP12390.1 - 0.016 14.8 8.3 0.016 14.8 8.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Mac-1 PF09028.10 CEP12390.1 - 0.2 10.7 0.1 0.27 10.3 0.1 1.1 1 0 0 1 1 1 0 Mac 1 Rtf2 PF04641.12 CEP12390.1 - 0.21 10.9 0.1 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger RINGv PF12906.7 CEP12390.1 - 0.31 11.2 5.9 1.3 9.2 5.9 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 CEP12390.1 - 0.7 9.8 5.0 1.3 8.9 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CEP12390.1 - 1.1 9.1 7.6 3.7 7.4 7.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Usp PF00582.26 CEP12391.1 - 3.8e-14 53.4 0.0 1e-13 52.0 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family PSCyt3 PF07627.11 CEP12391.1 - 0.047 14.0 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) AMP-binding PF00501.28 CEP12392.1 - 7.9e-95 317.9 0.0 9.7e-95 317.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP12392.1 - 5.3e-22 78.6 0.1 1.1e-21 77.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEP12392.1 - 4.5e-19 68.1 1.3 1.2e-18 66.7 0.2 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Lambda_CIII PF02061.16 CEP12392.1 - 0.16 12.1 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Lambda Phage CIII RhoGEF PF00621.20 CEP12393.1 - 3.5e-49 167.5 3.4 3.5e-49 167.5 3.4 3.2 3 0 0 3 3 3 1 RhoGEF domain SH3_1 PF00018.28 CEP12393.1 - 8.4e-20 70.1 2.1 2.2e-09 36.8 0.6 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CEP12393.1 - 2.6e-16 59.2 3.6 6.2e-08 32.4 0.7 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CEP12393.1 - 8.8e-14 50.9 0.1 4.9e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 CEP12393.1 - 1.6e-10 41.0 1.4 1.6e-10 41.0 1.4 5.8 3 2 2 6 6 6 1 Pleckstrin homology domain DUF3712 PF12505.8 CEP12394.1 - 1.9e-69 231.7 31.4 6.3e-24 84.6 1.6 6.3 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CEP12394.1 - 5e-10 39.8 7.6 0.026 15.1 0.0 7.5 8 0 0 8 8 8 4 Late embryogenesis abundant protein Tmemb_9 PF05434.11 CEP12394.1 - 0.055 13.4 0.0 0.055 13.4 0.0 1.6 2 0 0 2 2 2 0 TMEM9 UFD1 PF03152.14 CEP12395.1 - 3.8e-75 251.1 0.0 4.8e-75 250.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 CEP12395.1 - 0.19 12.0 0.0 1.3 9.2 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Tau95_N PF17682.1 CEP12396.1 - 0.11 12.7 2.5 0.37 11.0 0.2 2.5 3 0 0 3 3 3 0 Tau95 Triple barrel domain PX PF00787.24 CEP12398.1 - 1.7e-19 69.9 0.0 3.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 PX domain RAMPs PF03787.15 CEP12398.1 - 0.047 13.7 0.2 0.2 11.7 0.2 2.0 1 1 0 1 1 1 0 RAMP superfamily DUF5129 PF17173.4 CEP12398.1 - 0.088 11.9 0.7 0.12 11.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) RRM_1 PF00076.22 CEP12399.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP160 PF07918.11 CEP12399.1 - 2.3 8.0 4.8 1.2 8.9 0.1 2.5 3 0 0 3 3 3 0 CAP160 repeat SUIM_assoc PF16619.5 CEP12399.1 - 5.6 7.1 15.2 8.1 6.6 7.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CEP12401.1 - 1.5e-28 99.9 0.0 2.7e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12401.1 - 2.6e-12 46.6 0.0 4.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP12401.1 - 1.6e-09 37.1 1.2 2.8e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase ubiquitin PF00240.23 CEP12402.1 - 5.6e-27 93.3 1.1 3.4e-14 52.3 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEP12402.1 - 2.3e-13 49.8 0.7 4.6e-08 32.8 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEP12402.1 - 8.8e-05 22.9 2.1 0.031 14.7 0.0 2.8 1 1 1 2 2 2 2 Ubiquitin-like domain USP7_C2 PF14533.6 CEP12402.1 - 0.0013 18.5 0.1 0.018 14.8 0.0 2.0 1 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal Ubiquitin_4 PF18036.1 CEP12402.1 - 0.01 15.8 0.3 4.9 7.3 0.0 3.1 2 1 1 3 3 3 0 Ubiquitin-like domain YukD PF08817.10 CEP12402.1 - 0.025 15.2 0.0 0.045 14.5 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.8 CEP12402.1 - 0.044 14.3 0.1 5.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 KAsynt_C_assoc PF16197.5 CEP12402.1 - 0.051 14.0 0.1 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension DUF1729 PF08354.10 CEP12402.1 - 0.14 11.0 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Arrestin_C PF02752.22 CEP12403.1 - 8.8e-10 39.2 0.8 4.7e-05 23.9 0.1 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP12403.1 - 0.00055 20.0 0.0 0.0083 16.2 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Glyco_transf_22 PF03901.17 CEP12404.1 - 1.2e-35 123.6 29.5 1.5e-35 123.3 29.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glutaredoxin PF00462.24 CEP12404.1 - 4.4e-15 55.7 0.1 9.9e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CEP12404.1 - 0.01 16.2 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Abhydrolase_3 PF07859.13 CEP12405.1 - 1.4e-31 110.0 0.0 1.3e-21 77.4 0.0 3.0 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP12405.1 - 0.0026 16.7 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyoxalase_4 PF13669.6 CEP12405.1 - 0.1 12.9 0.0 0.54 10.5 0.0 2.2 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Med1 PF10744.9 CEP12406.1 - 6e-24 84.8 12.2 8.4e-16 58.0 0.5 3.1 2 1 1 3 3 3 2 Mediator of RNA polymerase II transcription subunit 1 Thoc2 PF11732.8 CEP12406.1 - 0.098 12.7 0.2 0.28 11.2 0.2 1.8 1 0 0 1 1 1 0 Transcription- and export-related complex subunit CLZ PF16526.5 CEP12406.1 - 0.32 11.4 4.0 0.53 10.7 1.8 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels F-box-like PF12937.7 CEP12407.1 - 5.3e-05 23.0 0.3 0.00014 21.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like Phage_Gp15 PF06854.11 CEP12407.1 - 0.00043 20.3 0.4 0.00089 19.3 0.4 1.5 1 0 0 1 1 1 1 Bacteriophage Gp15 protein Homez PF11569.8 CEP12407.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez E1-E2_ATPase PF00122.20 CEP12408.1 - 3.7e-20 72.2 0.0 1.5e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEP12408.1 - 7.7e-17 62.3 0.0 3.3e-10 40.6 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-MYND PF01753.18 CEP12408.1 - 4.8e-05 23.4 15.4 0.00011 22.3 15.4 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.28 CEP12408.1 - 0.00026 21.4 0.1 0.00096 19.6 0.0 2.0 2 1 0 2 2 2 1 SET domain Cation_ATPase PF13246.6 CEP12408.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP12408.1 - 0.041 13.6 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DAZAP2 PF11029.8 CEP12408.1 - 0.11 13.4 1.5 0.31 12.0 1.5 1.7 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) zf-C6H2 PF15801.5 CEP12408.1 - 3.3 8.1 14.1 8.1 6.8 14.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Kei1 PF08552.11 CEP12409.1 - 0.035 14.0 0.9 0.035 14.0 0.9 1.9 1 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MgtE PF01769.16 CEP12409.1 - 0.14 12.6 5.3 4.2 7.8 4.2 2.1 2 0 0 2 2 2 0 Divalent cation transporter DUF1003 PF06210.11 CEP12409.1 - 0.23 11.6 1.4 0.58 10.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) LRR19-TM PF15176.6 CEP12409.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain SRTM1 PF15872.5 CEP12409.1 - 4.2 7.6 6.1 1.7 8.9 1.9 2.0 1 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 RT_RNaseH_2 PF17919.1 CEP12411.1 - 1.1e-27 95.9 0.0 3.1e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP12411.1 - 4.4e-26 91.2 0.0 1.1e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP12411.1 - 5.1e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP12411.1 - 5.4e-12 45.7 0.2 1.7e-11 44.1 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP12411.1 - 1.7e-10 40.8 0.8 5.3e-10 39.3 0.8 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP12411.1 - 1.2e-07 31.5 0.3 3.1e-07 30.2 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP12411.1 - 0.0017 18.5 0.9 0.0064 16.7 0.9 2.1 1 0 0 1 1 1 1 H2C2 zinc finger DUF4286 PF14114.6 CEP12411.1 - 0.034 14.6 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF3884 PF13024.6 CEP12411.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) DDE_3 PF13358.6 CEP12412.1 - 5.6e-28 97.5 0.0 9e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP12412.1 - 2e-05 24.3 0.1 0.00025 20.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP12412.1 - 6.3e-05 23.5 0.0 0.00047 20.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP12412.1 - 0.016 15.3 0.1 0.042 14.0 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 CEP12412.1 - 0.062 13.3 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Stork_head PF10264.9 CEP12412.1 - 0.063 13.5 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain HTH_Tnp_ISL3 PF13542.6 CEP12412.1 - 0.13 11.7 0.3 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 zf-CCHC_5 PF14787.6 CEP12413.1 - 0.0023 17.6 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger DUF1287 PF06940.11 CEP12413.1 - 0.01 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Retrotrans_gag PF03732.17 CEP12414.1 - 6.8e-06 26.3 0.0 7.4e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Retrotransposon gag protein Mucin PF01456.17 CEP12417.1 - 0.013 15.5 12.1 0.013 15.5 12.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein ASH PF15780.5 CEP12417.1 - 0.032 14.4 2.1 0.077 13.2 2.1 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UDG PF03167.19 CEP12418.1 - 1.3e-24 87.0 0.1 1.9e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SMC_N PF02463.19 CEP12419.1 - 1.9e-64 217.1 20.6 1.7e-35 122.5 7.4 3.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CEP12419.1 - 1.1e-18 67.6 0.2 4.9e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CEP12419.1 - 4.6e-13 50.1 16.2 4.6e-13 50.1 16.2 6.4 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 CEP12419.1 - 1.1e-07 32.0 15.4 7.1e-05 22.8 0.1 4.4 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEP12419.1 - 0.00038 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CEP12419.1 - 0.00055 19.7 22.9 0.00055 19.7 22.9 4.7 2 2 1 3 3 3 1 AAA ATPase domain DehI PF10778.9 CEP12419.1 - 0.21 11.7 1.7 0.6 10.2 0.3 2.5 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI DUF4250 PF14056.6 CEP12419.1 - 2 8.4 7.6 0.95 9.5 0.3 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) SOAR PF16533.5 CEP12420.1 - 0.058 13.4 1.0 0.65 10.0 0.2 2.1 1 1 1 2 2 2 0 STIM1 Orai1-activating region Phage_coat PF09063.10 CEP12420.1 - 0.06 13.4 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage PP7 coat protein Transposase_21 PF02992.14 CEP12426.1 - 0.0013 18.0 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Exo_endo_phos PF03372.23 CEP12429.1 - 0.15 11.6 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CEP12431.1 - 3.3e-13 50.2 1.0 7.9e-13 48.9 0.4 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP12433.1 - 5.5e-31 107.8 0.0 1e-30 106.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_pp85 PF04637.12 CEP12434.1 - 0.075 11.5 4.8 0.11 10.9 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 CEP12434.1 - 2.4 7.7 8.9 3 7.4 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DFRP_C PF16543.5 CEP12435.1 - 7.7e-29 100.0 2.0 7.7e-29 100.0 2.0 4.0 3 2 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 CEP12435.1 - 2.9e-08 33.4 5.9 3.8e-08 33.0 0.8 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEP12435.1 - 1.6e-06 27.8 9.3 2.8e-06 27.0 1.8 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEP12435.1 - 0.00011 22.1 5.8 0.00011 22.1 5.8 3.2 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 CEP12435.1 - 0.0017 19.0 25.1 0.33 11.7 15.6 4.4 2 1 1 3 3 3 2 Torus domain TRA-1_regulated PF02343.16 CEP12435.1 - 0.019 15.0 0.7 0.083 13.0 0.1 2.1 2 0 0 2 2 2 0 TRA-1 regulated protein R03H10.4 zf-CCCH_2 PF14608.6 CEP12435.1 - 0.043 14.3 2.0 0.043 14.3 2.0 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger IspA PF04279.15 CEP12436.1 - 0.003 17.7 6.3 0.003 17.7 6.3 2.3 1 1 1 3 3 3 1 Intracellular septation protein A DUF3159 PF11361.8 CEP12436.1 - 2 8.1 13.3 8.5 6.1 13.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) MerC PF03203.14 CEP12436.1 - 2.5 8.6 12.1 35 4.9 12.1 2.5 1 1 0 1 1 1 0 MerC mercury resistance protein PHO4 PF01384.20 CEP12436.1 - 5.6 5.9 5.8 12 4.8 5.8 1.7 1 1 0 1 1 1 0 Phosphate transporter family CPSF73-100_C PF11718.8 CEP12437.1 - 4.7e-63 212.6 0.4 7.9e-63 211.9 0.3 1.5 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CEP12437.1 - 1.7e-32 112.0 0.0 4.6e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CEP12437.1 - 1.5e-17 63.2 0.0 3.5e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 CEP12437.1 - 3.2e-14 52.8 0.2 5.3e-13 48.8 0.0 2.7 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CEP12437.1 - 1e-08 35.5 0.1 2.1e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CEP12437.1 - 0.0063 16.4 0.1 0.021 14.7 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CEP12437.1 - 0.011 15.3 0.3 0.042 13.4 0.1 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CEP12437.1 - 0.027 13.7 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family Corona_nucleoca PF00937.18 CEP12438.1 - 0.076 12.0 1.6 0.096 11.7 1.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cyto_heme_lyase PF01265.17 CEP12438.1 - 1.3 8.5 5.9 1.8 8.1 5.8 1.3 1 1 0 1 1 1 0 Cytochrome c/c1 heme lyase IF4E PF01652.18 CEP12439.1 - 1.2e-26 93.5 0.0 2.5e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CCDC32 PF14989.6 CEP12439.1 - 0.02 14.9 1.2 0.02 14.9 1.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing 32 DUF2393 PF09624.10 CEP12439.1 - 0.024 14.6 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Gag_p15 PF08723.10 CEP12439.1 - 0.052 13.8 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Gag protein p15 DUF2423 PF10338.9 CEP12440.1 - 2.3e-10 40.5 6.3 2.3e-10 40.5 6.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 CEP12440.1 - 0.71 10.5 14.2 0.93 10.1 12.7 1.9 2 1 0 2 2 2 0 Learning-associated protein Atg31 PF09795.9 CEP12440.1 - 1 9.3 6.1 4.3 7.3 6.1 1.9 1 1 0 1 1 1 0 Autophagy-related protein 31 Voldacs PF03517.13 CEP12441.1 - 1.1e-26 93.7 1.4 1.8e-26 92.9 1.4 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF4448 PF14610.6 CEP12442.1 - 3.6e-07 30.1 1.1 1.2e-06 28.5 1.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 CEP12442.1 - 0.56 10.1 0.0 0.56 10.1 0.0 3.0 3 1 0 3 3 3 0 TMEM154 protein family Cyt-b5 PF00173.28 CEP12443.1 - 4.6e-23 81.1 0.2 4.6e-23 81.1 0.2 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CEP12443.1 - 9.2e-14 51.9 19.1 9.2e-14 51.9 19.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM189_B_dmain PF10520.9 CEP12443.1 - 1.9 8.6 10.4 0.65 10.1 2.9 2.6 3 0 0 3 3 3 0 B domain of TMEM189, localisation domain DDE_3 PF13358.6 CEP12444.1 - 7.7e-17 61.4 0.4 1.4e-16 60.6 0.4 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP12444.1 - 1.3e-16 60.6 0.7 2.9e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP12444.1 - 1.8e-07 31.7 1.4 4e-07 30.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP12444.1 - 4e-06 26.8 0.1 6.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP12444.1 - 0.00025 20.9 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 CEP12444.1 - 0.0012 18.4 0.1 0.085 12.4 0.0 3.1 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 CEP12444.1 - 0.0012 18.5 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP12444.1 - 0.0015 18.6 1.2 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP12444.1 - 0.0037 17.0 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP12444.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP12444.1 - 0.026 14.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_19 PF12844.7 CEP12444.1 - 0.13 12.2 2.1 16 5.6 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain SUR7 PF06687.12 CEP12445.1 - 1e-18 67.8 11.0 1e-18 67.8 11.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF2768 PF10966.8 CEP12445.1 - 0.03 14.8 10.0 0.03 14.8 10.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) DDE_3 PF13358.6 CEP12447.1 - 4.6e-19 68.6 0.3 3.8e-10 39.7 0.1 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease DAHP_snth_FXD PF18152.1 CEP12447.1 - 0.063 13.1 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Senescence PF06911.12 CEP12448.1 - 0.00032 21.1 20.1 0.00054 20.3 20.1 1.5 1 1 0 1 1 1 1 Senescence-associated protein EspB PF05802.11 CEP12448.1 - 0.16 11.9 13.9 2.9 7.8 13.9 2.3 1 1 0 1 1 1 0 Enterobacterial EspB protein DUF3833 PF12915.7 CEP12448.1 - 1 8.9 9.2 0.068 12.8 0.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3833) DUF3659 PF12396.8 CEP12448.1 - 8.5 6.4 25.9 1.9 8.5 1.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3659) DUF2076 PF09849.9 CEP12449.1 - 0.034 14.2 0.8 0.052 13.6 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MOZ_SAS PF01853.18 CEP12450.1 - 1.4e-84 282.3 0.6 1.8e-84 281.9 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEP12450.1 - 5.6e-20 70.7 7.0 1.5e-19 69.3 7.0 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CEP12450.1 - 0.001 19.4 0.0 0.0019 18.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP12450.1 - 0.0053 17.0 0.0 0.029 14.6 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family PX PF00787.24 CEP12450.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 PX domain HTH_11 PF08279.12 CEP12450.1 - 0.18 11.8 0.3 0.35 10.9 0.3 1.4 1 0 0 1 1 1 0 HTH domain Tudor-knot PF11717.8 CEP12451.1 - 1.1e-20 73.3 0.1 5.3e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain PBP1_TM PF14812.6 CEP12451.1 - 0.21 12.0 4.3 0.082 13.3 1.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sdh_cyt PF01127.22 CEP12452.1 - 5.2e-25 87.8 3.1 7.2e-25 87.4 3.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mito_carr PF00153.27 CEP12454.1 - 9.1e-68 224.3 4.0 1.8e-22 79.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CEP12454.1 - 7.1e-07 29.6 0.7 0.00019 21.8 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP12454.1 - 1.2e-05 24.8 0.4 2.1 8.5 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CEP12454.1 - 8e-05 22.4 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP12454.1 - 0.011 15.3 0.1 0.24 11.1 0.0 2.7 3 0 0 3 3 3 0 EF hand Serine_protease PF18405.1 CEP12454.1 - 0.024 13.8 0.2 0.31 10.2 0.0 2.6 2 1 0 3 3 3 0 Gammaproteobacterial serine protease ApoO PF09769.9 CEP12455.1 - 5.3e-28 97.6 7.6 1.9e-25 89.3 0.3 2.5 1 1 1 2 2 2 2 Apolipoprotein O Apolipoprotein PF01442.18 CEP12455.1 - 1.5e-07 31.5 4.8 6.8e-07 29.4 3.3 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PspA_IM30 PF04012.12 CEP12455.1 - 0.0012 18.4 1.8 0.0012 18.4 1.8 2.2 2 0 0 2 2 2 1 PspA/IM30 family RmuC PF02646.16 CEP12455.1 - 0.0092 15.1 4.9 0.15 11.2 0.1 3.0 2 1 1 3 3 3 1 RmuC family Tweety PF04906.13 CEP12455.1 - 0.011 14.5 0.9 0.011 14.5 0.9 1.7 2 0 0 2 2 2 0 Tweety Prominin PF05478.11 CEP12455.1 - 0.015 13.3 5.3 0.03 12.3 5.2 1.5 1 1 0 1 1 1 0 Prominin HisKA_3 PF07730.13 CEP12455.1 - 0.03 14.8 1.2 3.1 8.4 0.3 3.5 2 1 1 3 3 3 0 Histidine kinase ApoLp-III PF07464.11 CEP12455.1 - 0.046 13.8 15.8 0.43 10.7 8.3 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 CEP12455.1 - 0.051 13.6 10.6 1.9 8.5 0.7 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 CEP12455.1 - 0.052 13.6 6.2 0.056 13.5 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CEP12455.1 - 0.063 13.3 5.8 0.34 11.0 2.3 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus dCache_2 PF08269.11 CEP12455.1 - 0.099 11.8 9.7 1.2 8.3 4.8 2.3 2 1 0 2 2 2 0 Cache domain Fzo_mitofusin PF04799.13 CEP12455.1 - 0.12 11.9 7.7 0.027 14.0 3.6 1.9 2 1 0 2 2 2 0 fzo-like conserved region YfcL PF08891.11 CEP12455.1 - 0.15 12.5 2.3 2.1 8.7 0.8 2.4 2 0 0 2 2 2 0 YfcL protein DUF883 PF05957.13 CEP12455.1 - 0.16 12.6 12.3 2.3 8.9 0.7 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 CEP12455.1 - 0.2 11.8 10.8 0.088 13.0 4.6 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YtxH PF12732.7 CEP12455.1 - 0.46 11.1 18.4 0.074 13.6 4.9 3.9 3 1 1 4 4 4 0 YtxH-like protein ZYG-11_interact PF05884.12 CEP12455.1 - 0.48 9.8 2.8 0.47 9.8 0.8 1.7 2 0 0 2 2 2 0 Interactor of ZYG-11 DUF2681 PF10883.8 CEP12455.1 - 0.58 10.6 7.4 0.96 9.9 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) COG5 PF10392.9 CEP12455.1 - 0.62 10.2 6.3 1.9 8.6 2.3 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Lipase_GDSL_3 PF14606.6 CEP12455.1 - 0.74 9.9 4.1 0.37 10.9 1.1 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TMPIT PF07851.13 CEP12455.1 - 0.74 9.0 5.0 0.54 9.5 2.6 1.8 2 0 0 2 2 2 0 TMPIT-like protein COG2 PF06148.11 CEP12455.1 - 3.2 7.8 7.4 5.1 7.2 4.3 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 CEP12455.1 - 3.9 7.8 13.1 62 3.9 8.5 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CH PF00307.31 CEP12456.1 - 4.1e-22 78.4 0.0 5.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CEP12456.1 - 8e-06 25.4 4.4 1.4e-05 24.6 4.4 1.4 1 0 0 1 1 1 1 Calponin family repeat DUF1351 PF07083.11 CEP12456.1 - 0.034 13.9 0.2 0.058 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) CAMSAP_CH PF11971.8 CEP12456.1 - 0.057 13.2 0.0 0.096 12.5 0.0 1.4 1 1 0 1 1 1 0 CAMSAP CH domain PdaC PF13739.6 CEP12456.1 - 0.79 10.7 6.5 7.6 7.6 2.6 2.4 2 1 0 2 2 2 0 Deacetylase PdaC Myb_DNA-binding PF00249.31 CEP12457.1 - 3.7e-14 52.6 1.3 7.2e-14 51.7 0.5 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2 PF00096.26 CEP12457.1 - 3.7e-13 49.2 17.9 0.00025 21.3 0.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-bind_6 PF13921.6 CEP12457.1 - 6.3e-12 45.6 2.5 1.4e-11 44.5 1.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-H2C2_2 PF13465.6 CEP12457.1 - 4.3e-10 39.5 16.4 4.1e-06 27.0 0.7 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP12457.1 - 6.9e-09 35.8 15.1 0.01 16.6 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP12457.1 - 1.9e-05 24.5 13.8 0.0048 16.9 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger SLIDE PF09111.10 CEP12457.1 - 0.00022 21.2 0.2 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 1 SLIDE CHDCT2 PF08074.11 CEP12457.1 - 0.0011 19.2 0.2 0.0054 16.9 0.0 2.4 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain zf-C2H2_8 PF15909.5 CEP12457.1 - 0.0071 16.6 5.4 0.031 14.6 1.4 2.9 1 1 1 2 2 2 2 C2H2-type zinc ribbon UBA_4 PF14555.6 CEP12457.1 - 0.045 13.6 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 UBA-like domain Rap1_C PF11626.8 CEP12457.1 - 0.063 13.4 0.1 0.23 11.5 0.1 2.0 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_aberr PF17017.5 CEP12457.1 - 0.075 13.2 0.6 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2HE PF16278.5 CEP12457.1 - 0.12 12.8 9.8 6.6 7.3 2.0 3.8 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 CEP12457.1 - 1.3 9.4 7.0 3.8 7.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HLH PF00010.26 CEP12458.1 - 2.9e-14 52.8 0.8 1e-13 51.0 0.8 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GATA PF00320.27 CEP12459.1 - 5.3e-31 105.9 17.3 7e-16 57.5 2.7 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP12459.1 - 6.5e-05 22.4 5.7 0.011 15.3 1.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 CEP12459.1 - 0.00034 20.7 2.3 0.32 11.1 0.1 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 CEP12459.1 - 0.0004 20.4 1.6 0.87 9.8 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain TDP43_N PF18694.1 CEP12459.1 - 0.00084 19.1 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 Transactive response DNA-binding protein N-terminal domain Auto_anti-p27 PF06677.12 CEP12459.1 - 0.013 15.6 5.4 1.2 9.4 0.7 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 CEP12459.1 - 0.028 14.5 4.7 2.4 8.2 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 CEP12459.1 - 0.049 13.5 4.4 3.9 7.4 0.3 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Vps36-NZF-N PF16988.5 CEP12459.1 - 0.25 10.8 4.5 0.67 9.4 0.1 3.5 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PBP PF01161.20 CEP12460.1 - 5.5e-17 62.3 0.0 6.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.22 CEP12461.1 - 1.1e-48 164.9 0.2 1.3e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP12461.1 - 2.9e-28 98.5 0.0 6.1e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP12461.1 - 6.1e-10 38.8 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP12461.1 - 0.00099 18.7 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP12461.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RTA1 PF04479.13 CEP12462.1 - 9.8e-49 165.8 16.3 9.8e-49 165.8 16.3 1.3 1 1 0 1 1 1 1 RTA1 like protein MHYT PF03707.16 CEP12462.1 - 1.9 8.7 6.1 14 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat RTA1 PF04479.13 CEP12463.1 - 5e-48 163.5 12.5 5e-48 163.5 12.5 1.9 1 1 1 2 2 2 2 RTA1 like protein ISP1_C PF18161.1 CEP12464.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 ISP1 C-terminal Pal1 PF08316.11 CEP12464.1 - 0.0085 16.9 0.0 0.8 10.5 0.0 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein AbrB PF05145.12 CEP12464.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB LEAP-2 PF07359.11 CEP12464.1 - 3.3 7.6 7.0 0.4 10.5 2.3 2.0 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EB PF01683.18 CEP12464.1 - 6.8 7.1 22.9 2.8 8.3 9.3 3.6 3 1 0 3 3 3 0 EB module Sds3 PF08598.11 CEP12465.1 - 6.8e-19 68.7 13.3 6.8e-19 68.7 13.3 1.7 2 0 0 2 2 2 1 Sds3-like TFIIA PF03153.13 CEP12465.1 - 0.18 11.7 39.3 0.34 10.9 39.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1447 PF07288.11 CEP12465.1 - 0.21 11.7 5.7 3 7.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) SPX PF03105.19 CEP12465.1 - 8.7 6.1 52.9 0.01 15.8 29.7 2.1 1 1 0 2 2 2 0 SPX domain zf-RING_11 PF17123.5 CEP12466.1 - 1.4e-11 43.9 2.4 3.5e-11 42.6 2.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEP12466.1 - 1.2e-10 41.5 7.5 2.5e-10 40.5 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEP12466.1 - 3.8e-08 33.1 2.1 5.9e-08 32.4 1.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CEP12466.1 - 7.5e-08 32.3 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 CEP12466.1 - 6.5e-07 29.1 1.6 6.5e-07 29.1 1.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP12466.1 - 0.00012 22.1 1.7 0.0003 20.7 1.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP12466.1 - 0.0024 17.8 4.9 0.0024 17.8 4.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEP12466.1 - 0.016 15.5 10.0 0.053 13.8 8.9 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CEP12466.1 - 0.018 15.0 2.7 0.048 13.7 2.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2681 PF10883.8 CEP12466.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PHD PF00628.29 CEP12466.1 - 0.16 11.9 5.4 0.28 11.1 5.4 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CEP12466.1 - 0.17 12.1 6.8 0.64 10.2 6.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CEP12466.1 - 0.22 11.6 0.3 0.22 11.6 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 CEP12466.1 - 0.37 11.0 4.4 0.51 10.5 3.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CEP12466.1 - 0.44 10.2 7.6 0.91 9.2 7.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CEP12466.1 - 0.45 10.7 6.1 0.23 11.6 3.6 1.9 2 1 0 2 2 1 0 RING-variant domain zf-RING-like PF08746.11 CEP12466.1 - 1 9.8 5.3 2 8.8 5.3 1.5 1 0 0 1 1 1 0 RING-like domain RNase_P_Rpp14 PF01900.19 CEP12467.1 - 9.9e-19 67.5 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Aldo_ket_red PF00248.21 CEP12468.1 - 7.2e-52 176.4 0.1 3.1e-50 171.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.6 CEP12468.1 - 0.15 11.9 0.4 22 5.0 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_7 PF02796.15 CEP12468.1 - 0.33 11.1 1.5 0.66 10.1 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Aa_trans PF01490.18 CEP12469.1 - 1.6e-64 218.1 28.4 2e-64 217.8 28.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 CEP12469.1 - 0.0015 17.5 19.3 1.2 7.9 1.0 4.0 3 1 1 4 4 4 3 Spore germination protein Gp23 PF07068.11 CEP12469.1 - 0.2 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 Cytochrom_B_C PF00032.17 CEP12469.1 - 3.2 8.1 11.7 0.28 11.5 0.6 3.6 3 1 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Not3 PF04065.15 CEP12470.1 - 1.7e-89 299.2 30.6 2.6e-89 298.6 30.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CEP12470.1 - 5e-46 156.0 11.8 2.1e-45 154.0 11.8 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DHO_dh PF01180.21 CEP12470.1 - 0.22 10.7 0.3 0.35 10.0 0.3 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF948 PF06103.11 CEP12470.1 - 0.34 11.2 1.7 34 4.8 0.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SesA PF17107.5 CEP12470.1 - 1.2 9.3 5.9 0.19 12.0 0.5 2.4 2 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4407 PF14362.6 CEP12470.1 - 2.1 7.6 10.1 3.6 6.8 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) H-kinase_dim PF02895.14 CEP12470.1 - 2.3 8.7 4.5 0.67 10.4 0.3 2.3 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain MucBP PF06458.12 CEP12471.1 - 0.19 12.8 0.1 1 10.4 0.0 2.0 1 1 1 2 2 2 0 MucBP domain WASH-7_N PF14745.6 CEP12472.1 - 0.062 11.8 0.1 0.08 11.4 0.1 1.0 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal NiFeSe_Hases PF00374.19 CEP12472.1 - 0.073 12.0 0.1 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase CdiA_C_tRNase PF18664.1 CEP12472.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 CdiA C-terminal tRNase domain PrmA PF06325.13 CEP12472.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Tox-REase-5 PF15648.6 CEP12472.1 - 0.13 12.8 0.3 2.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 RVT_1 PF00078.27 CEP12473.1 - 3e-16 59.6 0.1 4.2e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP12474.1 - 6e-27 94.6 0.0 1.4e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP12474.1 - 3.3e-12 46.3 0.6 5.5e-11 42.3 0.1 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Metallothio_6 PF05522.11 CEP12475.1 - 0.19 12.3 1.8 16 6.1 0.1 2.3 2 0 0 2 2 2 0 Metallothionein zinc_ribbon_12 PF11331.8 CEP12475.1 - 0.51 10.2 4.4 14 5.6 0.3 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain Fer4_11 PF13247.6 CEP12475.1 - 1.4 9.0 4.4 23 5.2 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain vATP-synt_E PF01991.18 CEP12476.1 - 3.1e-59 199.7 11.6 3.7e-59 199.5 11.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ER PF01133.17 CEP12476.1 - 0.14 12.1 2.2 0.28 11.2 0.2 2.3 3 0 0 3 3 3 0 Enhancer of rudimentary LRR_8 PF13855.6 CEP12477.1 - 9e-35 118.3 40.8 9e-12 44.6 9.2 7.2 5 1 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 CEP12477.1 - 1.2e-19 70.1 49.6 6.6e-06 26.4 5.0 8.6 6 2 3 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP12477.1 - 6.7e-05 22.9 37.1 2.9 8.8 0.5 11.4 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.6 CEP12477.1 - 0.00056 19.5 24.0 0.014 14.9 4.5 4.6 2 1 2 5 5 5 3 Leucine-rich repeat Glyco_transf_15 PF01793.16 CEP12478.1 - 5.3e-83 278.9 11.6 6.5e-83 278.7 11.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-C2H2_4 PF13894.6 CEP12479.1 - 1.5e-09 37.9 53.5 0.025 15.4 1.5 7.6 7 1 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 CEP12479.1 - 1.2e-08 35.1 33.6 0.00015 22.0 1.0 7.8 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP12479.1 - 4.2e-08 33.3 30.4 0.0031 17.8 0.8 6.7 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEP12479.1 - 8.5e-07 29.3 18.3 0.2 12.0 0.3 5.3 4 1 0 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CEP12479.1 - 0.012 16.1 7.3 0.022 15.2 1.8 7.4 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CEP12479.1 - 0.018 14.8 0.4 0.018 14.8 0.4 5.6 6 1 0 6 6 6 0 zinc-finger C2H2-type C1_2 PF03107.16 CEP12479.1 - 0.063 13.6 18.8 20 5.6 1.0 6.3 5 1 1 6 6 6 0 C1 domain zf-LITAF-like PF10601.9 CEP12479.1 - 0.81 10.0 15.9 10 6.4 0.1 5.5 5 1 1 6 6 6 0 LITAF-like zinc ribbon domain DUF629 PF04780.12 CEP12479.1 - 0.86 8.1 13.0 3.6 6.0 0.7 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF629) zf-BED PF02892.15 CEP12479.1 - 2.6 8.1 19.6 1.6 8.8 0.1 6.1 6 1 0 6 6 6 0 BED zinc finger CSTF2_hinge PF14327.6 CEP12481.1 - 6.3e-27 93.9 5.0 6.3e-27 93.9 5.0 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CEP12481.1 - 5.5e-21 74.2 0.0 1.5e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CEP12481.1 - 3.1e-12 45.8 7.4 3.1e-12 45.8 7.4 3.3 4 1 1 5 5 5 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 CEP12481.1 - 0.0084 16.2 0.1 0.018 15.1 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif MgtE_N PF03448.17 CEP12481.1 - 0.27 11.9 1.8 3.7 8.2 0.0 3.0 4 0 0 4 4 4 0 MgtE intracellular N domain Extensin_2 PF04554.13 CEP12481.1 - 4.1 7.6 33.7 1.1 9.4 17.5 2.3 2 0 0 2 2 2 0 Extensin-like region TMEM208_SND2 PF05620.11 CEP12482.1 - 1.8e-56 190.6 1.8 2e-56 190.4 1.8 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Lgl_C PF08596.10 CEP12483.1 - 1.4e-14 53.6 0.0 8.7e-13 47.7 0.1 3.0 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 CEP12483.1 - 5e-08 33.5 6.4 0.0006 20.6 0.2 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12483.1 - 1.1e-06 28.8 0.1 0.051 13.9 0.0 5.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pex14_N PF04695.13 CEP12483.1 - 0.0065 17.1 6.4 0.0065 17.1 6.4 3.6 4 0 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Synaptobrevin PF00957.21 CEP12483.1 - 0.0084 15.9 0.3 0.02 14.7 0.3 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF2442 PF10387.9 CEP12483.1 - 0.029 14.7 0.0 3.8 7.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Ribosomal_L27 PF01016.19 CEP12484.1 - 2e-40 136.7 0.9 2.4e-40 136.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PDZ_1 PF12812.7 CEP12485.1 - 8.7e-28 96.2 0.0 2.3e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 CEP12485.1 - 7.4e-20 72.4 0.0 1.1e-15 58.8 0.0 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 CEP12485.1 - 4.5e-14 52.5 2.0 0.016 15.5 0.0 5.3 5 0 0 5 5 5 4 PDZ domain PDZ_6 PF17820.1 CEP12485.1 - 8.4e-09 35.1 0.6 0.037 13.9 0.0 5.1 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 CEP12485.1 - 5.4e-08 33.1 1.2 0.35 11.3 0.0 4.5 4 0 0 4 4 4 3 PDZ domain Peptidase_S7 PF00949.21 CEP12485.1 - 0.012 15.4 1.4 0.039 13.8 1.4 1.8 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 CEP12485.1 - 0.059 12.9 0.5 0.14 11.6 0.5 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 CEP12485.1 - 0.12 11.0 0.2 0.2 10.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase S46 Cupin_5 PF06172.11 CEP12485.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily (DUF985) Ribosomal_L27 PF01016.19 CEP12486.1 - 1.6e-26 92.1 0.2 2e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein DMRL_synthase PF00885.19 CEP12487.1 - 7.1e-51 171.7 0.1 1e-50 171.2 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Vps5 PF09325.10 CEP12488.1 - 3.5e-09 36.6 8.8 5.2e-09 36.0 8.8 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DUF4423 PF14394.6 CEP12488.1 - 0.0048 16.6 0.7 0.011 15.5 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) PX PF00787.24 CEP12488.1 - 0.066 13.2 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 PX domain Abhydrolase_1 PF00561.20 CEP12489.1 - 6.8e-09 35.8 0.2 5.6e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP12489.1 - 2.3e-08 34.9 0.0 3.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP12489.1 - 1.5e-06 27.7 0.0 0.00013 21.3 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Lipase PF00151.19 CEP12489.1 - 0.00012 21.5 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Lipase Thioesterase PF00975.20 CEP12489.1 - 0.002 18.3 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 CEP12489.1 - 0.0023 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CEP12489.1 - 0.0031 17.3 0.0 0.23 11.2 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF1057 PF06342.12 CEP12489.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S15 PF02129.18 CEP12489.1 - 0.019 14.6 0.0 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF676 PF05057.14 CEP12489.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 CEP12489.1 - 0.054 13.0 0.0 2.2 7.7 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CEP12489.1 - 0.058 13.2 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 CEP12490.1 - 2.5e-16 60.2 0.0 5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12490.1 - 1.6e-13 50.8 0.0 2.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP12490.1 - 8.5e-13 48.8 0.0 2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP12490.1 - 4.2e-12 46.1 0.1 6.6e-11 42.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12490.1 - 1.2e-08 35.6 0.0 2.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CEP12490.1 - 1.8e-05 24.1 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 CEP12490.1 - 4.5e-05 23.0 0.0 0.00021 20.8 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 CEP12490.1 - 5.2e-05 23.4 0.0 8.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 CEP12490.1 - 6.2e-05 21.8 0.0 0.00049 18.8 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 CEP12490.1 - 8.2e-05 22.1 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CEP12490.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 CEP12490.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MetW PF07021.12 CEP12490.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW bZIP_2 PF07716.15 CEP12492.1 - 5.2e-13 48.9 9.0 1e-12 47.9 4.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP12492.1 - 1.6e-09 37.7 6.0 1.6e-09 37.7 6.0 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 CEP12492.1 - 0.0002 21.8 4.2 0.00021 21.7 2.9 1.7 1 1 1 2 2 2 1 bZIP Maf transcription factor DivIC PF04977.15 CEP12492.1 - 0.017 14.8 1.3 0.017 14.8 1.3 1.7 1 1 0 1 1 1 0 Septum formation initiator HAUS-augmin3 PF14932.6 CEP12492.1 - 0.023 14.3 8.7 0.033 13.8 8.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 CEP12492.1 - 0.047 14.1 4.5 0.047 14.1 4.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Striatin PF08232.12 CEP12492.1 - 0.047 14.3 1.1 0.047 14.3 1.1 2.1 1 1 1 2 2 2 0 Striatin family CLZ PF16526.5 CEP12492.1 - 0.057 13.8 6.3 0.047 14.1 4.6 1.8 2 0 0 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CHDCT2 PF08074.11 CEP12492.1 - 0.081 13.1 3.4 0.37 11.0 3.3 1.9 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain HalX PF08663.10 CEP12492.1 - 0.13 12.6 3.5 0.5 10.7 3.5 2.1 1 1 0 1 1 1 0 HalX domain ABC_tran_CTD PF16326.5 CEP12492.1 - 0.16 12.2 5.2 10 6.5 0.5 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 CEP12492.1 - 0.18 12.3 7.4 0.3 11.6 7.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 CEP12492.1 - 0.2 10.9 6.8 0.28 10.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Hemagglutinin PF00509.18 CEP12492.1 - 0.28 9.5 1.7 0.37 9.2 1.7 1.1 1 0 0 1 1 1 0 Haemagglutinin M PF02370.16 CEP12492.1 - 0.38 11.5 5.9 2.4 9.0 0.4 3.5 2 1 1 3 3 3 0 M protein repeat Spc7 PF08317.11 CEP12492.1 - 0.39 9.6 9.6 0.55 9.1 9.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CEP12492.1 - 0.42 10.7 13.2 0.95 9.5 6.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.6 CEP12492.1 - 1.5 8.9 9.1 2.3 8.3 9.1 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 NAD_binding_10 PF13460.6 CEP12493.1 - 8.5e-15 55.1 0.0 3.3e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CEP12493.1 - 1.8e-14 53.8 0.4 1.6e-13 50.8 0.4 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CEP12493.1 - 8.5e-06 25.4 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CEP12493.1 - 0.00026 20.5 0.1 0.00098 18.6 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 CEP12493.1 - 0.0025 18.1 0.2 0.0057 16.9 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CEP12493.1 - 0.034 14.6 0.0 0.095 13.1 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 CEP12493.1 - 0.047 13.9 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Vac14_Fig4_bd PF11916.8 CEP12494.1 - 2.3e-80 268.5 10.0 2.3e-80 268.5 10.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CEP12494.1 - 4.9e-46 155.3 0.3 4.1e-40 136.3 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CEP12494.1 - 1.1e-09 37.7 2.5 0.019 15.2 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 CEP12494.1 - 1.6e-07 31.2 0.1 8.6 6.6 0.0 5.9 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEP12494.1 - 9.4e-07 29.2 1.2 0.6 10.7 0.1 6.4 6 1 1 7 7 7 1 HEAT-like repeat Cnd1 PF12717.7 CEP12494.1 - 0.00081 19.5 4.9 0.51 10.4 0.2 4.4 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Zip PF02535.22 CEP12494.1 - 1.7 7.8 10.2 0.61 9.2 1.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RasGEF_N_2 PF14663.6 CEP12494.1 - 2 8.8 7.2 13 6.2 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TFIIA PF03153.13 CEP12494.1 - 2.9 7.8 24.5 4.4 7.2 7.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CEP12494.1 - 3 8.3 10.3 0.77 10.2 2.2 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF913 PF06025.12 CEP12494.1 - 3.4 6.5 10.3 0.25 10.3 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RhoGEF PF00621.20 CEP12495.1 - 0.0052 17.0 10.2 0.95 9.7 0.5 4.7 3 1 1 4 4 4 3 RhoGEF domain Myb_DNA-binding PF00249.31 CEP12496.1 - 1.4e-09 37.9 3.4 0.00027 21.1 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP12496.1 - 3.3e-08 33.6 5.5 0.00043 20.5 1.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CEP12496.1 - 0.024 14.7 0.4 0.049 13.7 0.4 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 CEP12496.1 - 0.024 14.6 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 SLIDE DUF1518 PF07469.12 CEP12496.1 - 0.35 11.3 3.4 0.75 10.2 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) PUL PF08324.11 CEP12497.1 - 3.4e-47 161.0 2.0 6.3e-47 160.1 2.0 1.5 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CEP12497.1 - 4.1e-39 133.4 0.6 1.1e-38 132.0 0.6 1.8 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CEP12497.1 - 1.4e-29 101.7 10.6 2.4e-06 28.2 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat HATPase_c PF02518.26 CEP12497.1 - 5.4e-28 97.7 0.0 1.5e-27 96.3 0.0 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP12497.1 - 1.2e-27 96.3 0.1 1.1e-26 93.2 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 CEP12497.1 - 5.7e-22 78.2 0.0 4.5e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CEP12497.1 - 4e-19 69.0 0.0 1.1e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.25 CEP12497.1 - 3.6e-16 58.9 0.0 1.3e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Peripla_BP_4 PF13407.6 CEP12497.1 - 2.3e-13 50.3 2.9 1.5e-08 34.6 0.1 3.0 3 0 0 3 3 3 2 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 CEP12497.1 - 0.00017 21.1 0.0 0.0077 15.7 0.0 2.5 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family BBS2_Mid PF14783.6 CEP12497.1 - 0.00038 20.5 0.0 0.081 13.0 0.0 2.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region SKG6 PF08693.10 CEP12497.1 - 0.047 13.1 3.2 0.11 12.0 3.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LIG3_BRCT PF16759.5 CEP12497.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain VSP PF03302.13 CEP12497.1 - 0.26 10.1 9.6 0.48 9.2 9.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein FmiP_Thoc5 PF09766.9 CEP12497.1 - 0.54 9.5 3.4 0.76 9.0 1.9 1.9 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 NCD3G PF07562.14 CEP12497.1 - 0.76 9.8 5.3 0.32 11.0 2.1 2.1 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 CEP12497.1 - 1 9.2 11.0 0.59 9.9 7.7 2.4 2 1 0 2 2 1 0 Putative ephrin-receptor like MFS_1 PF07690.16 CEP12498.1 - 2.9e-50 171.2 30.5 1.2e-46 159.2 16.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP12498.1 - 3e-13 49.5 10.0 3e-13 49.5 10.0 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEP12498.1 - 2.7e-08 32.7 8.6 5.2e-08 31.8 8.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CEP12498.1 - 0.0053 15.1 9.8 0.0027 16.1 4.5 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF4231 PF14015.6 CEP12498.1 - 0.088 13.3 0.6 0.088 13.3 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) MFS_3 PF05977.13 CEP12498.1 - 0.43 8.9 13.1 0.0073 14.8 5.7 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector PIP5K PF01504.18 CEP12499.1 - 2.1e-97 325.7 2.6 2.1e-97 325.7 2.6 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-C2H2 PF00096.26 CEP12499.1 - 4e-09 36.4 11.0 0.00018 21.8 1.7 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP12499.1 - 6.6e-07 29.5 8.6 4.6e-06 26.8 2.4 3.0 2 0 0 2 2 2 1 Zinc-finger double domain FOXP-CC PF16159.5 CEP12499.1 - 2.3e-05 24.9 5.8 0.0082 16.7 0.2 3.2 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CEP12499.1 - 0.0005 20.7 14.7 0.0021 18.7 1.4 4.3 4 0 0 4 4 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP12499.1 - 0.0033 17.7 3.7 0.0048 17.1 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding SART-1 PF03343.13 CEP12499.1 - 0.011 14.4 0.1 0.011 14.4 0.1 2.3 2 0 0 2 2 2 0 SART-1 family zf_ZIC PF18366.1 CEP12499.1 - 0.094 12.8 0.5 0.87 9.7 0.0 2.8 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 CEP12499.1 - 0.11 12.9 1.9 0.33 11.3 1.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 CEP12499.1 - 0.12 12.8 0.2 0.12 12.8 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEP12499.1 - 0.13 12.3 0.7 0.43 10.6 0.7 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Hexokinase_2 PF03727.16 CEP12500.1 - 8.8e-68 228.3 0.0 1.2e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP12500.1 - 6.1e-47 160.1 0.0 8.9e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase NTF2 PF02136.20 CEP12501.1 - 9.6e-30 103.6 0.1 9.6e-30 103.6 0.1 2.4 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CEP12501.1 - 1.1e-11 44.4 0.1 2.3e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.7 CEP12502.1 - 2.6e-08 34.0 0.1 4.4e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP12502.1 - 8.7e-08 32.3 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 CEP12502.1 - 0.00037 20.5 0.9 0.0023 18.0 0.9 2.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 CEP12502.1 - 0.003 17.3 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 U1 zinc finger zf_C2H2_ZHX PF18387.1 CEP12502.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain F-box-like PF12937.7 CEP12503.1 - 3.9e-08 33.1 0.1 2.1e-07 30.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP12503.1 - 7.3e-08 32.1 0.1 1.2e-06 28.2 0.0 3.0 2 0 0 2 2 2 1 F-box domain Methyltransf_11 PF08241.12 CEP12504.1 - 2.2e-14 53.9 0.0 5.1e-14 52.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP12504.1 - 1.7e-11 44.7 0.0 6.2e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12504.1 - 1.1e-07 31.9 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP12504.1 - 3.7e-07 30.1 0.0 8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12504.1 - 3.7e-06 27.6 0.0 1.3e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP12504.1 - 2.8e-05 23.5 0.0 6.7e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 CEP12504.1 - 0.0063 15.5 0.0 0.027 13.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 CEP12504.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Staphopain_pro PF14731.6 CEP12505.1 - 0.067 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Staphopain proregion Sortilin-Vps10 PF15902.5 CEP12505.1 - 0.079 11.7 0.0 0.086 11.6 0.0 1.0 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, SPRY PF00622.28 CEP12509.1 - 1.1e-23 83.7 1.3 1.8e-22 79.7 0.5 2.6 2 0 0 2 2 2 1 SPRY domain Arm PF00514.23 CEP12509.1 - 9.3e-09 35.0 0.7 0.11 12.6 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CEP12509.1 - 7.9e-05 23.2 4.7 0.51 11.0 0.1 4.5 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 CEP12509.1 - 0.0002 21.3 0.1 0.0019 18.2 0.1 2.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 CEP12509.1 - 0.0016 18.9 0.0 0.13 12.8 0.1 3.0 2 0 0 2 2 2 1 HEAT-like repeat V-ATPase_H_C PF11698.8 CEP12509.1 - 0.02 15.0 1.4 0.14 12.2 0.1 3.0 2 0 0 2 2 2 0 V-ATPase subunit H KDZ PF18758.1 CEP12510.1 - 1e-32 113.6 0.9 3.5e-32 111.8 0.9 1.8 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP12510.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Herpes_UL4 PF03277.13 CEP12510.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF1391 PF07151.12 CEP12511.1 - 0.045 13.6 0.3 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) PIF1 PF05970.14 CEP12512.1 - 1.1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP12512.1 - 3.8e-05 21.8 0.0 4.4e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP12512.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain RT_RNaseH_2 PF17919.1 CEP12513.1 - 2.5e-33 114.1 0.0 5.3e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP12513.1 - 6.3e-32 110.0 0.1 3.9e-31 107.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP12513.1 - 1.2e-17 63.8 0.2 2.5e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP12513.1 - 5.2e-17 62.1 0.0 1.3e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP12513.1 - 0.034 13.9 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Kinesin PF00225.23 CEP12514.1 - 8.1e-99 330.7 0.1 8.1e-99 330.7 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 CEP12514.1 - 3.5e-54 183.7 2.3 3.5e-54 183.7 2.3 3.3 3 0 0 3 3 3 1 Kinesin-associated DUF3694 PF12473.8 CEP12514.1 - 2.3e-42 145.3 0.0 1.3e-41 142.8 0.0 2.4 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 CEP12514.1 - 7.8e-28 97.3 0.0 2.5e-27 95.6 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 CEP12514.1 - 4.1e-08 33.4 0.1 3.6e-07 30.5 0.1 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 CEP12514.1 - 3e-07 30.8 0.1 3e-07 30.8 0.1 2.9 4 0 0 4 4 3 1 Kinesin protein 1B PH PF00169.29 CEP12514.1 - 4.3e-05 24.0 0.0 0.0002 21.8 0.0 2.2 2 0 0 2 2 2 1 PH domain Yop-YscD_cpl PF16697.5 CEP12514.1 - 5.7e-05 23.4 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PTSIIB_sorb PF03830.15 CEP12514.1 - 0.056 13.7 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 PTS system sorbose subfamily IIB component DUF4611 PF15387.6 CEP12514.1 - 5.6 7.2 8.9 0.23 11.7 2.0 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CEP12514.1 - 6.8 5.9 10.0 0.037 13.3 0.3 2.0 2 0 0 2 2 1 0 NOA36 protein NAD_binding_10 PF13460.6 CEP12515.1 - 9.6e-10 38.6 0.0 2.6e-09 37.2 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CEP12515.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family TIR_2 PF13676.6 CEP12515.1 - 0.041 14.5 0.1 0.19 12.3 0.0 2.1 2 1 0 2 2 2 0 TIR domain 3Beta_HSD PF01073.19 CEP12515.1 - 0.047 12.7 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Arylesterase PF01731.20 CEP12516.1 - 1.7e-09 37.8 0.9 5.6e-09 36.1 0.3 2.2 2 0 0 2 2 2 1 Arylesterase UQ_con PF00179.26 CEP12517.1 - 3.4e-54 182.3 0.0 3.8e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP12517.1 - 0.0026 18.0 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CEP12517.1 - 0.009 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEP12517.1 - 0.058 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF846 PF05832.12 CEP12518.1 - 4.1e-54 182.4 10.4 5.1e-54 182.1 10.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 CEP12518.1 - 0.27 10.5 0.5 1.4 8.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) RseC_MucC PF04246.12 CEP12518.1 - 5.6 6.9 6.3 9.5 6.2 1.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Zn_clus PF00172.18 CEP12519.1 - 5.7e-08 32.8 7.1 1.1e-07 31.8 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FoP_duplication PF13865.6 CEP12520.1 - 5.1e-13 49.4 21.9 3.3e-11 43.6 21.9 2.3 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Palm_thioest PF02089.15 CEP12522.1 - 1.1e-35 123.7 1.5 1.1e-35 123.7 1.5 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase OKR_DC_1_N PF03709.15 CEP12523.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribosomal_L35p PF01632.19 CEP12524.1 - 6.3e-18 65.0 1.1 7.7e-18 64.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 zf-C4H2 PF10146.9 CEP12525.1 - 6.4e-11 43.0 16.0 7.6e-11 42.7 16.0 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein DUF2110 PF09883.9 CEP12525.1 - 0.022 14.4 1.5 0.03 13.9 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) LAMTOR PF15454.6 CEP12525.1 - 0.033 14.8 0.8 0.033 14.8 0.8 2.2 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4606 PF15379.6 CEP12525.1 - 0.098 12.9 6.7 0.031 14.5 2.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4606) Baculo_PEP_C PF04513.12 CEP12525.1 - 0.19 11.8 4.4 0.19 11.8 2.7 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-K PF11802.8 CEP12525.1 - 1.2 8.6 18.3 1.5 8.3 18.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Methyltransf_25 PF13649.6 CEP12526.1 - 1.8e-11 44.6 0.0 3.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP12526.1 - 1.5e-08 35.2 0.0 3.1e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP12526.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12526.1 - 3e-06 27.2 0.0 5.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP12526.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP12526.1 - 0.00078 20.1 0.0 0.0021 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP12526.1 - 0.015 14.7 0.0 0.056 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase ProQ_C PF17516.2 CEP12526.1 - 0.15 11.5 0.1 0.88 9.0 0.0 2.0 2 0 0 2 2 2 0 ProQ C-terminal domain SHQ1 PF04925.15 CEP12527.1 - 4.1e-68 228.4 2.9 6.3e-68 227.8 2.9 1.3 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.16 CEP12527.1 - 0.11 13.5 0.0 0.3 12.1 0.0 1.8 1 0 0 1 1 1 0 CS domain zf-RVT PF13966.6 CEP12528.1 - 2.7e-06 28.0 1.0 4.4e-06 27.3 1.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CCDC24 PF15669.5 CEP12529.1 - 0.055 13.3 1.5 0.1 12.5 1.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Colicin_Pyocin PF01320.18 CEP12529.1 - 0.062 13.4 1.0 0.15 12.2 1.0 1.7 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein zf-RING_2 PF13639.6 CEP12531.1 - 1.7e-11 44.3 7.8 2.5e-11 43.7 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEP12531.1 - 9.6e-09 35.4 4.2 2e-08 34.4 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP12531.1 - 4.3e-08 32.9 7.6 6.7e-08 32.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP12531.1 - 2.7e-07 30.3 3.2 4e-07 29.8 3.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP12531.1 - 2.2e-06 27.6 4.9 4e-06 26.7 4.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP12531.1 - 7.1e-06 25.8 4.3 1.2e-05 25.1 4.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEP12531.1 - 1.1e-05 25.2 6.6 1.8e-05 24.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEP12531.1 - 1.2e-05 24.9 1.4 2.5e-05 23.9 1.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CEP12531.1 - 0.002 18.0 4.7 0.0044 16.9 4.8 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP12531.1 - 0.002 18.1 3.7 0.0053 16.8 3.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TFIIIC PF12660.7 CEP12531.1 - 0.004 17.1 2.5 0.01 15.8 2.5 1.6 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex U-box PF04564.15 CEP12531.1 - 0.024 14.8 0.0 0.083 13.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.8 CEP12531.1 - 0.031 14.1 2.2 0.058 13.2 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 CEP12531.1 - 0.16 11.6 3.5 0.27 10.9 3.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 CEP12531.1 - 0.18 12.0 3.2 0.44 10.7 3.2 1.7 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CEP12531.1 - 0.27 11.4 4.5 0.77 10.0 4.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CEP12531.1 - 0.61 9.9 3.8 1.1 9.2 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3020 PF11223.8 CEP12532.1 - 2.1e-15 56.9 5.5 2.1e-15 56.9 5.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3020) DDE_3 PF13358.6 CEP12534.1 - 1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DEAD PF00270.29 CEP12535.1 - 1e-38 132.9 0.1 2.2e-38 131.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP12535.1 - 7.5e-27 93.9 0.2 1.6e-23 83.2 0.1 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CEP12535.1 - 1.1e-09 38.5 0.1 5.2e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP12535.1 - 0.0016 18.7 0.9 0.14 12.4 0.4 3.3 1 1 1 2 2 2 1 AAA domain GCR1_C PF12550.8 CEP12536.1 - 5.6e-22 77.8 1.2 7.4e-22 77.5 1.2 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 CEP12537.1 - 1.5e-12 47.2 0.0 1.6e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RRM_1 PF00076.22 CEP12538.1 - 3.3e-40 135.7 0.0 1.1e-16 60.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP12538.1 - 1.9e-06 27.5 0.0 0.22 11.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP12538.1 - 0.00011 22.1 0.0 0.00038 20.4 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEP12538.1 - 0.0018 18.4 1.8 0.013 15.5 0.0 3.2 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 CEP12538.1 - 0.0027 17.7 0.0 0.0027 17.7 0.0 2.9 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 CEP12538.1 - 0.0031 17.3 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif AAA_23 PF13476.6 CEP12538.1 - 1.7 9.1 12.6 1.5 9.3 1.0 2.3 2 0 0 2 2 2 0 AAA domain TERB2 PF15101.6 CEP12538.1 - 3.4 7.7 22.9 4.6 7.2 4.5 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PAF-AH_p_II PF03403.13 CEP12539.1 - 6e-66 222.5 0.0 5.5e-65 219.3 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CEP12539.1 - 6e-13 48.3 0.0 1.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CEP12539.1 - 1e-07 31.5 0.5 1.2e-06 28.0 0.5 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CEP12539.1 - 2.4e-07 30.4 0.0 1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 CEP12539.1 - 1.4e-05 24.2 0.0 0.00069 18.7 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_1 PF00561.20 CEP12539.1 - 2.4e-05 24.1 0.2 0.00022 20.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP12539.1 - 0.00035 21.3 0.0 0.00051 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CEP12539.1 - 0.0036 16.9 0.0 0.017 14.7 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 CEP12539.1 - 0.014 15.2 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 CEP12539.1 - 0.19 11.6 0.2 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Lipase (class 3) CoA_binding PF02629.19 CEP12540.1 - 8.2e-31 106.6 2.5 1.1e-30 106.1 1.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CEP12540.1 - 2.3e-22 79.4 0.1 4.8e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CEP12540.1 - 4.3e-06 26.6 0.0 8.8e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CEP12540.1 - 0.00014 22.4 0.1 0.00036 21.0 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Rer1 PF03248.13 CEP12541.1 - 9.3e-77 256.6 7.2 1.9e-76 255.6 7.2 1.5 1 0 0 1 1 1 1 Rer1 family SIKE PF05769.11 CEP12541.1 - 0.53 10.2 13.3 0.9 9.4 12.5 1.8 1 1 1 2 2 2 0 SIKE family Tweety PF04906.13 CEP12541.1 - 0.91 8.1 6.2 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Tweety Mucin PF01456.17 CEP12543.1 - 2.9 7.9 18.1 0.18 11.8 8.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Tetraspanin PF00335.20 CEP12544.1 - 2.8e-08 33.8 3.5 4.1e-08 33.2 3.5 1.2 1 0 0 1 1 1 1 Tetraspanin family MAP17 PF15807.5 CEP12544.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TRP PF06011.12 CEP12544.1 - 0.035 12.8 0.1 0.037 12.8 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Aim19 PF10315.9 CEP12545.1 - 1.7e-28 99.2 3.1 2.3e-28 98.8 3.1 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Peptidase_M13_N PF05649.13 CEP12546.1 - 4.2e-69 234.1 3.5 3.1e-68 231.2 0.1 2.4 2 0 0 2 2 2 1 Peptidase family M13 SPX PF03105.19 CEP12546.1 - 1.7e-45 156.6 16.5 3.3e-45 155.7 16.5 1.5 1 0 0 1 1 1 1 SPX domain Peptidase_M13 PF01431.21 CEP12546.1 - 2.4e-42 144.9 0.0 4.4e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 zf-C3HC4_4 PF15227.6 CEP12546.1 - 8.8e-07 29.0 8.3 1.8e-06 28.0 8.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CEP12546.1 - 3.7e-06 26.7 9.6 8.8e-06 25.5 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP12546.1 - 5.9e-06 26.1 7.3 1.4e-05 24.9 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEP12546.1 - 8.5e-06 25.5 8.6 1.7e-05 24.5 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP12546.1 - 9.2e-06 25.4 8.9 2.4e-05 24.1 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP12546.1 - 2.3e-05 24.3 5.2 5.7e-05 23.1 5.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEP12546.1 - 2.6e-05 24.5 12.2 3.4e-05 24.1 9.1 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CEP12546.1 - 0.00048 19.9 9.0 0.0012 18.7 9.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP12546.1 - 0.034 14.4 5.5 0.097 13.0 5.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CEP12546.1 - 0.21 11.7 4.7 0.64 10.2 4.7 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CEP12546.1 - 0.34 10.7 8.2 0.045 13.5 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CEP12546.1 - 5 7.1 5.5 17 5.4 5.5 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein EphA2_TM PF14575.6 CEP12547.1 - 9.2e-05 23.2 1.1 0.00035 21.4 1.1 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 CEP12547.1 - 0.016 15.0 0.7 0.027 14.2 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 CEP12547.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E K1 PF02960.14 CEP12547.1 - 0.042 14.0 1.3 1.6 8.9 0.1 2.4 2 1 1 3 3 3 0 K1 glycoprotein TMEM51 PF15345.6 CEP12547.1 - 0.081 12.8 0.1 0.081 12.8 0.1 2.2 1 1 0 2 2 2 0 Transmembrane protein 51 DUF4064 PF13273.6 CEP12547.1 - 0.081 13.2 0.6 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2269 PF10027.9 CEP12547.1 - 0.082 13.0 0.3 0.082 13.0 0.3 1.5 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Phage_holin_7_1 PF16081.5 CEP12547.1 - 0.12 12.6 0.7 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MscS_TM PF12794.7 CEP12547.1 - 0.13 11.1 1.5 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 RIFIN PF02009.16 CEP12547.1 - 0.14 12.0 0.3 0.28 11.0 0.0 1.6 1 1 1 2 2 2 0 Rifin LapA_dom PF06305.11 CEP12547.1 - 1.5 8.7 6.8 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Cadherin_C_2 PF16492.5 CEP12547.1 - 2.2 9.1 4.6 1.5 9.6 0.8 2.5 2 1 1 3 3 3 0 Cadherin cytoplasmic C-terminal Sel1 PF08238.12 CEP12548.1 - 9.7e-21 73.8 3.9 2e-07 31.4 0.8 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_3 PF07720.12 CEP12548.1 - 0.00071 19.5 4.4 0.11 12.6 1.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12548.1 - 0.08 12.8 1.6 1 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12548.1 - 1 9.7 0.0 1 9.7 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CEP12549.1 - 1.4e-16 60.6 0.4 2.9e-16 59.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12549.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP12549.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TPT PF03151.16 CEP12550.1 - 6.9e-13 48.6 4.5 7.8e-13 48.4 4.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CEP12550.1 - 1e-06 28.2 6.3 1.1e-06 28.1 6.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEP12550.1 - 3.4e-06 27.3 10.1 4.5e-06 26.9 10.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family Tmemb_14 PF03647.13 CEP12550.1 - 0.37 11.6 5.8 0.13 13.0 3.2 1.6 2 0 0 2 2 2 0 Transmembrane proteins 14C HTH_23 PF13384.6 CEP12551.1 - 3.9e-08 32.9 0.0 2.2e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP12551.1 - 0.00082 19.5 0.3 0.0017 18.4 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 CEP12551.1 - 0.0019 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 CEP12551.1 - 0.0035 16.7 0.1 0.0085 15.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 CEP12551.1 - 0.005 17.4 0.0 0.3 11.7 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEP12551.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Transposase Stork_head PF10264.9 CEP12551.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DDE_3 PF13358.6 CEP12552.1 - 7.7e-20 71.1 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HIT PF01230.23 CEP12552.1 - 0.15 12.8 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 HIT domain TRAPPC9-Trs120 PF08626.11 CEP12553.1 - 0 1117.9 5.1 0 1117.8 5.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CEP12553.1 - 0.0026 18.0 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12553.1 - 0.026 14.4 0.1 0.067 13.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEP12553.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 CEP12553.1 - 0.041 14.0 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CWC25 PF12542.8 CEP12553.1 - 0.32 11.9 2.7 0.97 10.4 2.7 1.8 1 0 0 1 1 1 0 Pre-mRNA splicing factor ATG16 PF08614.11 CEP12554.1 - 1.7e-43 149.2 33.6 1.7e-43 149.2 33.6 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 CEP12554.1 - 2e-38 129.7 15.3 4.4e-06 27.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12554.1 - 5.6e-17 61.8 4.9 0.0084 16.4 0.0 7.0 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP12554.1 - 3e-11 43.6 0.1 0.0091 15.9 0.0 3.6 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP12554.1 - 3.6e-07 29.5 3.0 0.12 11.3 0.0 4.5 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP12554.1 - 1.1e-06 27.6 7.5 0.28 9.8 0.1 5.3 1 1 3 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP12554.1 - 0.00027 20.4 0.3 0.83 8.9 0.0 3.6 2 1 0 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 CEP12554.1 - 0.00049 18.7 0.1 0.0019 16.8 0.0 2.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain TMF_DNA_bd PF12329.8 CEP12554.1 - 0.014 15.3 12.1 0.014 15.3 12.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding PD40 PF07676.12 CEP12554.1 - 0.068 13.1 0.3 12 6.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 CEP12554.1 - 0.12 12.3 1.6 11 6.1 0.1 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Golgin_A5 PF09787.9 CEP12554.1 - 0.34 10.3 29.2 0.33 10.4 28.1 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 fragilysinNterm PF16376.5 CEP12554.1 - 0.7 9.6 5.6 3 7.6 1.4 3.4 2 1 0 3 3 3 0 N-terminal domain of fragilysin Alpha-2-MRAP_C PF06401.11 CEP12554.1 - 2 8.3 21.5 1.8 8.5 20.0 1.5 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF16 PF01519.16 CEP12554.1 - 4.6 7.8 26.0 0.35 11.4 11.0 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 Pyrophosphatase PF00719.19 CEP12555.1 - 2.2e-55 186.9 0.7 3.3e-55 186.3 0.5 1.4 2 0 0 2 2 2 1 Inorganic pyrophosphatase NFACT-R_1 PF05670.13 CEP12556.1 - 3.1e-26 92.2 0.0 8.2e-26 90.8 0.0 1.7 1 1 0 1 1 1 1 NFACT protein RNA binding domain TFX_C PF14601.6 CEP12556.1 - 0.073 13.0 0.2 0.27 11.2 0.0 2.1 2 1 0 2 2 2 0 DNA_binding protein, TFX, C-term Nop25 PF09805.9 CEP12557.1 - 6e-23 81.8 18.4 8.9e-23 81.3 18.4 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Spem1 PF15670.5 CEP12557.1 - 4.4 6.8 6.4 6.2 6.3 6.3 1.4 1 1 0 1 1 1 0 Spermatid maturation protein 1 BPL_N PF09825.9 CEP12557.1 - 4.5 6.3 7.5 5.4 6.0 7.5 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal UPF0560 PF10577.9 CEP12557.1 - 6.5 5.1 9.0 7.4 4.9 9.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 6PF2K PF01591.18 CEP12559.1 - 5.7e-69 231.8 0.1 8.8e-69 231.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP12559.1 - 5.7e-35 120.8 0.0 1.3e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) BCDHK_Adom3 PF10436.9 CEP12560.1 - 2.3e-44 151.1 2.0 4.1e-44 150.3 2.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEP12560.1 - 9.6e-12 45.4 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP12560.1 - 0.05 13.4 0.1 0.21 11.4 0.0 2.1 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MRAP PF15183.6 CEP12561.1 - 1.1 9.3 3.7 5.8 6.9 0.0 3.0 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Thiolase_C PF02803.18 CEP12562.1 - 1.8e-09 37.3 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 CEP12562.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain MRG PF05712.13 CEP12563.1 - 4.6e-46 156.6 2.5 8.3e-46 155.8 2.5 1.3 1 1 0 1 1 1 1 MRG Fumble PF03630.14 CEP12564.1 - 3.8e-132 440.5 0.3 6.3e-132 439.7 0.3 1.3 1 0 0 1 1 1 1 Fumble Tyr_Deacylase PF02580.16 CEP12564.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Adaptin_N PF01602.20 CEP12565.1 - 2.5e-127 425.6 5.5 3.3e-127 425.2 5.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CEP12565.1 - 6.1e-31 106.9 0.0 1.8e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CEP12565.1 - 4.9e-12 46.1 0.7 8.9e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain FHA PF00498.26 CEP12566.1 - 2.9e-15 56.4 0.1 6.1e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CEP12566.1 - 2.4e-11 43.2 9.4 4.4e-11 42.3 9.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEP12566.1 - 8.2e-09 35.7 7.9 1.4e-08 34.9 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CEP12566.1 - 2.8e-05 23.6 3.5 5.8e-05 22.6 3.5 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 CEP12566.1 - 0.00046 20.0 7.4 0.00086 19.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 CEP12566.1 - 0.00076 19.8 1.5 0.0011 19.2 0.0 2.0 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain Prok-RING_4 PF14447.6 CEP12566.1 - 0.0025 17.6 3.9 0.0064 16.3 3.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP12566.1 - 0.0028 17.9 4.2 0.0028 17.9 4.2 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP12566.1 - 0.0032 17.3 8.4 0.0057 16.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEP12566.1 - 0.0035 17.4 1.4 0.0076 16.3 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CEP12566.1 - 0.0057 16.6 6.3 0.015 15.2 6.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP12566.1 - 0.015 15.3 8.7 0.041 13.9 8.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP12566.1 - 0.018 14.9 3.9 0.031 14.1 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEP12566.1 - 0.059 13.0 3.3 0.11 12.2 3.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CEP12566.1 - 0.13 12.1 2.7 0.27 11.2 2.7 1.6 1 0 0 1 1 1 0 PHD-finger Spt20 PF12090.8 CEP12566.1 - 0.14 11.7 27.1 0.021 14.4 17.7 2.4 2 0 0 2 2 2 0 Spt20 family SpoVR PF04293.13 CEP12566.1 - 1 8.0 7.0 1.5 7.4 7.0 1.2 1 0 0 1 1 1 0 SpoVR like protein EPL1 PF10513.9 CEP12566.1 - 1.6 9.1 10.3 4.1 7.8 7.0 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4746 PF15928.5 CEP12566.1 - 1.6 8.1 9.3 2.7 7.3 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PH_4 PF15404.6 CEP12566.1 - 2.8 7.7 5.3 73 3.1 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Ufd2P_core PF10408.9 CEP12566.1 - 2.8 6.4 7.0 4.4 5.8 7.0 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core FYDLN_acid PF09538.10 CEP12566.1 - 4.1 8.1 11.2 0.92 10.2 6.9 2.2 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 CEP12566.1 - 4.3 6.6 12.0 0.86 8.9 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Neur_chan_memb PF02932.16 CEP12566.1 - 7.3 6.6 7.0 1 9.4 0.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF853 PF05872.12 CEP12566.1 - 7.4 5.0 8.0 11 4.5 8.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SLC12 PF03522.15 CEP12566.1 - 7.8 5.4 11.2 0.4 9.6 5.6 1.6 2 0 0 2 2 2 0 Solute carrier family 12 DUF4578 PF15147.6 CEP12566.1 - 8.7 7.2 16.7 2.5 9.0 12.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) Metallophos PF00149.28 CEP12567.1 - 7e-12 46.3 0.1 1.1e-11 45.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP12567.1 - 7.3e-06 26.3 0.1 2.8e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SNARE PF05739.19 CEP12567.1 - 0.011 15.7 1.5 0.025 14.6 1.5 1.5 1 0 0 1 1 1 0 SNARE domain DUF2140 PF09911.9 CEP12567.1 - 0.028 14.0 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Sigma_reg_N PF13800.6 CEP12567.1 - 0.038 14.3 0.1 0.07 13.4 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF1616 PF07760.11 CEP12567.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF929 PF06053.11 CEP12567.1 - 0.051 12.9 2.2 0.083 12.2 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) 7TM_GPCR_Str PF10326.9 CEP12567.1 - 0.057 12.8 0.1 0.083 12.2 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str EphA2_TM PF14575.6 CEP12567.1 - 0.063 14.2 0.3 0.15 12.9 0.1 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Chordopox_A33R PF05966.12 CEP12567.1 - 0.12 11.7 0.3 0.19 11.0 0.3 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein PhoLip_ATPase_C PF16212.5 CEP12567.1 - 0.13 12.0 0.3 0.19 11.5 0.3 1.2 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Shisa PF13908.6 CEP12567.1 - 0.21 11.8 0.3 0.36 11.1 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UPF0258 PF06789.12 CEP12567.1 - 0.67 10.1 2.8 1.1 9.4 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Sulfate_transp PF00916.20 CEP12568.1 - 1.1e-109 366.7 22.4 1.4e-109 366.4 22.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP12568.1 - 2e-06 27.4 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP12568.1 - 5.9e-06 26.7 3.2 5.9e-06 26.7 3.2 3.2 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily SpoIIIAC PF06686.11 CEP12568.1 - 0.052 13.7 1.4 0.24 11.6 1.4 2.2 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family DUF1633 PF07794.11 CEP12569.1 - 3.1 5.9 6.9 3.3 5.8 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Asp PF00026.23 CEP12570.1 - 7.2e-112 373.9 0.0 8.6e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP12570.1 - 4.3e-13 49.9 1.5 6.2e-11 42.8 0.5 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP12570.1 - 0.00075 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP12570.1 - 0.02 15.5 0.0 8 7.2 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease Ribosomal_L6e PF01159.19 CEP12571.1 - 6e-37 126.6 0.2 6e-37 126.6 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CEP12571.1 - 4.8e-10 39.5 0.4 4.8e-10 39.5 0.4 2.4 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain KOW PF00467.29 CEP12571.1 - 0.083 12.9 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 KOW motif DUF1899 PF08953.11 CEP12573.1 - 5.1e-32 109.6 0.3 9.9e-32 108.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CEP12573.1 - 3.3e-23 81.3 0.4 6.8e-23 80.3 0.4 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CEP12573.1 - 2.2e-21 75.7 0.1 0.00026 21.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12573.1 - 1.3e-07 31.8 0.4 0.00067 19.9 0.0 3.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 CEP12573.1 - 0.00051 19.8 7.9 0.00074 19.3 7.9 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 CEP12573.1 - 0.012 15.9 9.6 0.018 15.3 9.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 CEP12573.1 - 0.018 14.7 4.5 0.029 14.0 4.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tropomyosin_1 PF12718.7 CEP12573.1 - 0.035 14.2 11.5 0.059 13.5 11.5 1.3 1 0 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.10 CEP12573.1 - 0.3 11.2 2.7 0.55 10.4 2.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CEP12573.1 - 0.36 11.3 10.8 0.64 10.5 10.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 CEP12573.1 - 0.83 9.7 8.8 1.1 9.3 8.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CEP12573.1 - 2.1 9.1 4.5 3.8 8.2 4.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF4611 PF15387.6 CEP12574.1 - 1.5e-05 25.1 5.0 1.8e-05 24.9 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Gon7 PF08738.10 CEP12574.1 - 0.0038 17.3 3.7 0.0038 17.3 3.7 1.9 1 1 0 1 1 1 1 Gon7 family Acylphosphatase PF00708.18 CEP12574.1 - 0.044 14.2 1.5 0.058 13.8 1.5 1.4 1 1 0 1 1 1 0 Acylphosphatase PI3K_1B_p101 PF10486.9 CEP12574.1 - 0.097 10.4 5.2 0.11 10.3 5.2 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CSN5_C PF18323.1 CEP12574.1 - 0.17 12.8 4.5 0.24 12.3 4.5 1.2 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain RhoGAP PF00620.27 CEP12575.1 - 7.2e-47 159.0 0.1 1.3e-46 158.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CEP12575.1 - 5.3e-15 55.8 0.1 1.3e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 CEP12575.1 - 3.5e-14 52.1 1.0 9.9e-14 50.7 1.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP12575.1 - 2.8e-12 46.3 0.1 6.3e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CEP12575.1 - 3.2e-11 43.1 1.2 7.7e-11 41.9 1.2 1.7 1 0 0 1 1 1 1 WW domain PH_9 PF15410.6 CEP12575.1 - 1.6e-10 41.4 0.1 5.7e-10 39.6 0.0 2.0 1 1 1 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 CEP12575.1 - 1.9e-10 40.3 0.4 6.7e-10 38.5 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain Rax2 PF12768.7 CEP12576.1 - 1.8e-27 96.2 3.9 2.8e-25 89.0 0.0 5.0 5 1 1 6 6 6 1 Cortical protein marker for cell polarity SH3_9 PF14604.6 CEP12576.1 - 6.6e-06 25.9 0.1 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP12576.1 - 0.00048 19.7 0.1 0.00091 18.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF5122 PF17164.4 CEP12576.1 - 1.1 9.7 0.0 1.1 9.7 0.0 5.7 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller zf-C2H2 PF00096.26 CEP12577.1 - 0.00021 21.6 22.7 0.0011 19.3 3.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP12577.1 - 0.016 15.6 3.9 0.016 15.6 3.9 4.9 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEP12577.1 - 0.044 14.1 12.1 0.46 10.8 2.3 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF719 PF05334.13 CEP12577.1 - 0.13 12.4 5.9 2.9 8.0 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) MPM1 PF17234.2 CEP12577.1 - 0.57 10.4 13.0 0.98 9.7 9.2 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 zf-C2H2_4 PF13894.6 CEP12577.1 - 3.1 8.9 18.8 2.7 9.1 2.8 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger Folate_carrier PF01770.18 CEP12577.1 - 4 6.1 5.8 1.1 7.9 1.5 1.9 2 0 0 2 2 2 0 Reduced folate carrier ALMT PF11744.8 CEP12577.1 - 4.8 5.9 6.9 0.7 8.7 2.3 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Roughex PF06020.11 CEP12577.1 - 6.1 5.8 11.5 11 5.0 11.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4175 PF13779.6 CEP12577.1 - 7.6 4.3 18.1 0.087 10.7 9.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) AAA_5 PF07728.14 CEP12578.1 - 2.7e-89 296.3 0.0 5.2e-35 120.4 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP12578.1 - 6.5e-09 36.4 3.2 0.04 14.3 0.1 5.4 3 2 1 5 5 5 2 AAA ATPase domain CbbQ_C PF08406.10 CEP12578.1 - 2.4e-06 27.7 0.1 0.0025 18.0 0.1 2.9 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_3 PF07726.11 CEP12578.1 - 4.3e-05 23.4 0.1 1.6 8.6 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEP12578.1 - 0.0026 18.0 2.4 4 7.7 0.1 4.1 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 CEP12578.1 - 0.0054 17.1 0.2 4.7 7.7 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MCM6_C PF18263.1 CEP12578.1 - 0.0059 16.8 0.2 0.38 11.0 0.0 3.3 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain RuvB_N PF05496.12 CEP12578.1 - 0.039 13.7 0.1 0.25 11.1 0.1 2.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_7 PF17867.1 CEP12578.1 - 0.094 12.9 0.2 1 9.6 0.2 2.7 2 0 0 2 2 2 0 Midasin AAA lid domain RNA_helicase PF00910.22 CEP12578.1 - 0.1 13.0 0.0 5.1 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CEP12578.1 - 0.11 11.9 0.5 8.7 5.7 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CEP12578.1 - 0.11 12.5 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_8 PF12780.7 CEP12578.1 - 0.19 11.0 0.5 4 6.7 0.4 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 RabGAP-TBC PF00566.18 CEP12579.1 - 7e-51 172.9 0.1 7e-51 172.9 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain BING4CT PF08149.11 CEP12580.1 - 0.095 12.5 0.0 0.39 10.6 0.0 1.7 1 1 0 2 2 2 0 BING4CT (NUC141) domain Peptidase_M28 PF04389.17 CEP12581.1 - 1.3e-33 116.4 0.0 2.5e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 CEP12581.1 - 7e-07 28.5 0.0 3.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase DUF5591 PF17884.1 CEP12581.1 - 0.00046 20.1 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) Peptidase_M20 PF01546.28 CEP12581.1 - 0.0032 17.2 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MS_channel PF00924.18 CEP12581.1 - 0.063 12.8 2.8 0.16 11.5 2.8 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel Ribosomal_L19 PF01245.20 CEP12582.1 - 6.2e-20 71.2 0.1 1.1e-19 70.5 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 XG_FTase PF03254.13 CEP12583.1 - 8.2e-08 31.3 0.0 0.0005 18.8 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase HTH_28 PF13518.6 CEP12586.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 CEP12586.1 - 0.062 13.9 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.6 CEP12586.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1439 PF07273.12 CEP12586.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1439) Cpn60_TCP1 PF00118.24 CEP12588.1 - 2e-156 521.5 13.0 2.3e-156 521.3 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 CEP12588.1 - 0.0022 18.3 1.4 0.025 14.9 0.1 3.3 3 1 0 4 4 4 1 Dinitrogenase iron-molybdenum cofactor EAL PF00563.20 CEP12588.1 - 0.021 14.3 0.1 0.05 13.1 0.1 1.6 1 0 0 1 1 1 0 EAL domain TPP_enzyme_M PF00205.22 CEP12588.1 - 0.07 12.9 0.2 0.22 11.3 0.2 1.9 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain PrpR_N PF06506.11 CEP12588.1 - 0.09 12.3 1.3 0.37 10.4 0.3 2.4 2 0 0 2 2 2 0 Propionate catabolism activator Pox_VLTF3 PF04947.14 CEP12588.1 - 0.098 12.4 0.4 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like CRS1_YhbY PF01985.21 CEP12588.1 - 0.22 11.7 1.7 3.2 8.0 0.4 3.1 3 1 0 3 3 3 0 CRS1 / YhbY (CRM) domain DUF2660 PF10859.8 CEP12588.1 - 0.24 11.9 1.0 0.91 10.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2660) Diphthami_syn_2 PF01902.17 CEP12589.1 - 3e-37 128.2 0.0 7.7e-37 126.9 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CEP12589.1 - 3.9e-27 94.7 0.0 4.2e-13 49.4 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP Erv26 PF04148.13 CEP12590.1 - 2.4e-59 200.6 19.4 8.5e-59 198.8 19.4 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF5056 PF16479.5 CEP12590.1 - 0.19 12.0 1.0 0.37 11.1 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5056) ATP-grasp PF02222.22 CEP12591.1 - 1.4e-64 216.8 0.1 2.8e-64 215.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.20 CEP12591.1 - 5.2e-62 207.8 3.2 1.5e-61 206.3 3.2 1.9 1 0 0 1 1 1 1 AIR carboxylase PurK_C PF17769.1 CEP12591.1 - 2.7e-19 68.6 0.1 5.6e-19 67.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CEP12591.1 - 6.3e-07 29.1 0.1 1.1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 CEP12591.1 - 2.2e-05 24.1 0.1 0.00014 21.5 0.1 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 CEP12591.1 - 2.5e-05 24.1 0.1 4.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AlaDh_PNT_C PF01262.21 CEP12591.1 - 0.00014 21.3 0.8 0.00042 19.7 0.6 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_5 PF13549.6 CEP12591.1 - 0.0002 20.9 0.3 0.0022 17.5 0.1 2.5 1 1 0 2 2 2 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 CEP12591.1 - 0.0057 16.0 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CEP12591.1 - 0.0058 16.5 0.6 0.014 15.3 0.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 CEP12591.1 - 0.014 15.5 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain XdhC_C PF13478.6 CEP12591.1 - 0.019 15.5 0.6 0.39 11.2 0.6 2.6 1 1 0 1 1 1 0 XdhC Rossmann domain EELM2 PF15863.5 CEP12591.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Extended EGL-27 and MTA1 homology domain Pyr_redox PF00070.27 CEP12591.1 - 0.23 12.0 1.1 1.2 9.8 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase CLP1_P PF16575.5 CEP12592.1 - 4.6e-51 173.3 0.4 1.4e-50 171.7 0.4 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CEP12592.1 - 1.3e-36 124.7 0.1 2.4e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CEP12592.1 - 2.5e-36 124.6 0.0 4.4e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_24 PF13479.6 CEP12592.1 - 0.02 14.6 0.0 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CEP12592.1 - 0.031 14.3 0.2 0.5 10.5 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_35 PF14516.6 CEP12592.1 - 0.033 13.0 0.0 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 CEP12592.1 - 0.037 13.4 0.2 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 CEP12592.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CEP12592.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CEP12592.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PCI PF01399.27 CEP12593.1 - 2.1e-13 50.7 0.0 7.4e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 PCI domain ANAPC3 PF12895.7 CEP12593.1 - 0.043 14.0 2.4 3.5 7.9 0.4 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CEP12593.1 - 0.045 14.4 0.0 0.99 10.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP12593.1 - 0.078 13.3 0.1 5.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2532 PF10811.8 CEP12593.1 - 0.095 12.8 0.8 0.33 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2532) TPR_2 PF07719.17 CEP12593.1 - 0.26 11.5 4.7 1.5 9.1 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12593.1 - 0.42 10.5 2.4 7 6.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HECT PF00632.25 CEP12594.1 - 6e-98 328.1 0.1 8.7e-98 327.6 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CEP12594.1 - 3.6e-36 122.9 19.7 1.3e-12 47.6 0.9 4.3 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CEP12594.1 - 5.2e-16 58.8 1.5 1.4e-15 57.4 1.4 1.9 1 1 0 1 1 1 1 C2 domain ubiquitin PF00240.23 CEP12596.1 - 2.6e-18 65.5 0.2 3.8e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP12596.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 CEP12596.1 - 0.00026 21.3 0.5 0.00026 21.3 0.5 1.4 1 1 0 1 1 1 1 Blt1 N-terminal domain DUF2407 PF10302.9 CEP12596.1 - 0.00033 21.2 0.0 0.00054 20.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP12596.1 - 0.0025 17.9 0.1 0.0051 16.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like bZIP_2 PF07716.15 CEP12598.1 - 2.1e-07 30.9 5.5 2.8e-07 30.5 4.7 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP12598.1 - 2.2e-05 24.5 7.1 3.6e-05 23.8 7.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor Macoilin PF09726.9 CEP12598.1 - 0.0049 15.5 11.9 0.0061 15.2 11.9 1.0 1 0 0 1 1 1 1 Macoilin family NEMO PF11577.8 CEP12598.1 - 0.079 13.0 2.0 0.19 11.8 2.0 1.7 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO bZIP_Maf PF03131.17 CEP12598.1 - 3.5 8.2 13.5 0.26 11.8 6.1 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor TFIIA PF03153.13 CEP12598.1 - 4.9 7.0 11.4 5.8 6.8 11.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYRC PF05965.14 CEP12599.1 - 1.3e-14 54.1 0.0 2.7e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CEP12599.1 - 2.5e-14 52.9 0.5 4.8e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 F/Y-rich N-terminus TelA PF05816.11 CEP12599.1 - 0.038 13.1 2.0 0.056 12.5 2.0 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) ADIP PF11559.8 CEP12599.1 - 0.059 13.5 4.6 0.11 12.6 4.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 CEP12599.1 - 0.07 12.5 5.0 0.12 11.7 5.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NES_C_h PF18208.1 CEP12601.1 - 0.049 13.9 1.7 0.089 13.1 1.7 1.4 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain Actin PF00022.19 CEP12602.1 - 1.8e-83 280.4 0.0 1.9e-82 277.1 0.0 1.9 1 1 0 1 1 1 1 Actin PilM_2 PF11104.8 CEP12602.1 - 0.16 11.0 0.0 5.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Asp PF00026.23 CEP12603.1 - 4.5e-41 141.3 1.6 5.5e-21 75.3 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP12603.1 - 1e-06 29.1 10.4 6.6e-06 26.5 1.0 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal MSP1_C PF07462.11 CEP12603.1 - 1.1 7.8 4.8 1.7 7.2 4.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SSP160 PF06933.11 CEP12603.1 - 9.2 4.3 19.2 14 3.7 19.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2887 PF11103.8 CEP12604.1 - 0.025 14.6 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) PDDEXK_2 PF12784.7 CEP12604.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase COX16 PF14138.6 CEP12605.1 - 0.39 11.3 3.2 0.94 10.0 3.2 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Elongin_A PF06881.11 CEP12605.1 - 0.44 11.1 7.3 0.32 11.5 4.8 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FAR1 PF03101.15 CEP12606.1 - 1.3e-05 25.8 2.1 2.1e-05 25.1 2.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Prefoldin PF02996.17 CEP12607.1 - 1.1e-32 112.4 2.8 1.1e-32 112.4 2.8 1.4 2 0 0 2 2 2 1 Prefoldin subunit YqhG PF11079.8 CEP12607.1 - 0.024 13.6 0.4 0.093 11.7 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein YqhG of unknown function End3 PF12761.7 CEP12607.1 - 0.16 12.1 3.5 0.82 9.8 3.5 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_2 PF01920.20 CEP12607.1 - 0.19 11.7 5.6 2.4 8.2 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit AAA_assoc_C PF09821.9 CEP12607.1 - 0.21 12.1 2.4 2.6 8.6 0.2 2.6 2 1 1 3 3 3 0 C-terminal AAA-associated domain MMgT PF10270.9 CEP12608.1 - 4.3e-16 59.1 0.2 5.5e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF4431 PF14485.6 CEP12608.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Peptidase_M16 PF00675.20 CEP12608.1 - 0.07 13.1 0.0 0.09 12.8 0.0 1.3 1 1 0 1 1 1 0 Insulinase (Peptidase family M16) MOR2-PAG1_N PF14222.6 CEP12609.1 - 1.1e-191 638.6 0.5 1.6e-191 638.0 0.5 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 CEP12609.1 - 2.1e-69 234.3 12.9 1.6e-29 102.3 0.5 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 CEP12609.1 - 2.2e-58 198.1 0.4 2.2e-58 198.1 0.4 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal FF PF01846.19 CEP12610.1 - 3.3e-40 136.0 12.5 1.7e-11 44.1 0.0 6.9 7 0 0 7 7 7 5 FF domain WW PF00397.26 CEP12610.1 - 2.9e-14 52.8 23.4 6e-09 35.8 6.2 2.9 3 0 0 3 3 3 2 WW domain MMM1 PF10296.9 CEP12611.1 - 3e-77 259.9 5.1 3.6e-71 239.9 0.2 2.8 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Slu7 PF11708.8 CEP12612.1 - 3.3e-109 364.8 16.3 3.3e-109 364.8 16.3 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 CEP12612.1 - 0.045 13.5 0.4 0.091 12.5 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle U3_snoRNA_assoc PF08297.11 CEP12612.1 - 6.5 7.5 11.0 0.44 11.3 0.2 3.8 3 1 1 4 4 4 0 U3 snoRNA associated SAP PF02037.27 CEP12613.1 - 2.3e-11 43.1 0.1 3.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 SAP domain BPL_LplA_LipB PF03099.19 CEP12614.1 - 1.4e-08 34.8 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NPCC PF08058.11 CEP12615.1 - 0.058 13.4 1.9 0.11 12.5 1.9 1.4 1 0 0 1 1 1 0 Nuclear pore complex component Cyto_heme_lyase PF01265.17 CEP12616.1 - 1.5e-70 238.1 22.6 2.2e-68 231.0 22.6 2.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Mso1_Sec1_bdg PF14475.6 CEP12616.1 - 0.047 13.3 0.2 2e+02 1.7 0.0 4.2 4 0 0 4 4 4 0 Sec1-binding region of Mso1 WH2 PF02205.20 CEP12617.1 - 6.5e-07 29.0 2.5 1.1e-06 28.3 1.6 1.9 2 0 0 2 2 2 1 WH2 motif UPF0121 PF03661.13 CEP12618.1 - 4.5e-37 127.8 5.1 5.4e-37 127.5 5.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TRAM_LAG1_CLN8 PF03798.16 CEP12619.1 - 1.2e-05 25.2 15.6 3e-05 23.8 15.8 1.5 1 1 0 1 1 1 1 TLC domain tRNA-synt_1b PF00579.25 CEP12620.1 - 2.4e-78 263.4 0.0 3.1e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CEP12620.1 - 2.5e-05 23.9 0.0 5.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 CEP12620.1 - 0.0023 17.7 0.2 0.11 12.3 0.2 2.4 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain RNB PF00773.19 CEP12621.1 - 2.5e-76 257.1 0.1 4.9e-76 256.2 0.1 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEP12621.1 - 1.8e-21 75.9 0.0 4.2e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEP12621.1 - 1.8e-13 50.6 0.0 1.8e-12 47.4 0.0 2.8 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 CEP12621.1 - 0.0067 16.1 0.1 0.024 14.3 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain MCM PF00493.23 CEP12622.1 - 1.1e-101 338.6 0.7 1.7e-101 338.0 0.7 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CEP12622.1 - 1.1e-40 138.4 0.8 2.1e-40 137.5 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CEP12622.1 - 1.1e-19 70.9 0.3 3.5e-19 69.3 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM6_C PF18263.1 CEP12622.1 - 1.1e-15 57.7 2.5 3.8e-15 56.0 2.5 2.0 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CEP12622.1 - 2.3e-15 56.8 6.1 1.6e-14 54.1 3.3 3.1 2 1 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CEP12622.1 - 3.5e-08 33.1 0.0 6.2e-07 29.0 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CEP12622.1 - 6.8e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEP12622.1 - 0.00093 19.2 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEP12622.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Glyco_hydro_31 PF01055.26 CEP12624.1 - 8.3e-137 457.0 11.3 1.3e-136 456.3 11.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CEP12624.1 - 1.3e-22 79.9 0.1 3.6e-22 78.5 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CEP12624.1 - 8.8e-06 25.9 0.9 4.8e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Ribosomal_S17 PF00366.20 CEP12625.1 - 2.6e-28 97.9 3.3 3e-28 97.7 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 PCB_OB PF17092.5 CEP12625.1 - 0.025 15.3 0.0 0.029 15.1 0.0 1.1 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain Glutaredoxin PF00462.24 CEP12626.1 - 4.3e-32 110.1 0.0 2.9e-15 56.2 0.0 2.9 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 CEP12626.1 - 8.7e-19 67.4 0.0 2.8e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CEP12626.1 - 1.9e-06 27.1 0.0 3.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Phosducin Thioredoxin_8 PF13905.6 CEP12626.1 - 1.4e-05 25.3 0.1 0.037 14.4 0.0 3.6 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CEP12626.1 - 0.00025 21.5 0.3 0.056 13.9 0.1 3.7 2 2 2 4 4 4 1 Thioredoxin-like domain HyaE PF07449.11 CEP12626.1 - 0.0029 17.6 0.0 0.24 11.4 0.0 3.3 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE RdRP PF05183.12 CEP12626.1 - 0.0038 15.9 0.0 1.9 7.0 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase EF-hand_13 PF17958.1 CEP12626.1 - 0.0062 16.3 0.0 11 5.9 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain SH3BGR PF04908.15 CEP12626.1 - 0.007 16.5 0.0 3.4 7.9 0.0 2.7 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Thioredoxin_7 PF13899.6 CEP12626.1 - 0.11 12.7 0.0 5.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 CEP12626.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.5 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family zf-LITAF-like PF10601.9 CEP12627.1 - 3.5e-19 68.8 6.1 4.9e-19 68.4 6.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_CPXG PF14255.6 CEP12627.1 - 0.0058 16.5 3.0 0.22 11.5 0.7 2.4 2 0 0 2 2 2 1 Cysteine-rich CPXCG Sgf11 PF08209.11 CEP12627.1 - 0.0076 15.8 2.0 4.8 6.8 0.1 3.0 3 0 0 3 3 3 2 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.10 CEP12627.1 - 0.013 15.6 0.5 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_7 PF02591.15 CEP12627.1 - 0.024 14.8 1.9 0.24 11.6 0.1 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 CEP12627.1 - 0.037 13.5 1.4 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CEP12627.1 - 0.047 13.7 0.5 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2396 PF09654.10 CEP12627.1 - 0.12 12.5 0.9 0.57 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) UPF0547 PF10571.9 CEP12627.1 - 0.33 11.1 3.9 2.7 8.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 CEP12627.1 - 0.54 10.2 3.2 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.12 CEP12627.1 - 0.95 9.5 5.4 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ndc1_Nup PF09531.10 CEP12627.1 - 1.4 7.5 5.3 1.5 7.4 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4211 PF13926.6 CEP12628.1 - 1.4e-17 64.0 0.2 1.2e-16 61.1 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4211) Eco57I PF07669.11 CEP12628.1 - 0.03 14.8 0.6 0.1 13.1 0.2 2.1 2 0 0 2 2 2 0 Eco57I restriction-modification methylase Rhomboid PF01694.22 CEP12629.1 - 5.1e-32 111.0 14.0 5.1e-32 111.0 14.0 2.6 2 1 1 3 3 3 1 Rhomboid family DUF5518 PF17647.1 CEP12629.1 - 0.019 15.1 7.1 0.019 15.1 7.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Hexapep PF00132.24 CEP12630.1 - 2.7e-07 30.0 15.2 0.00075 19.1 3.2 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CEP12630.1 - 0.013 14.4 2.7 0.41 9.5 0.3 2.0 1 1 1 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 CEP12630.1 - 1.7 8.5 16.9 0.16 11.7 1.4 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Rhomboid PF01694.22 CEP12631.1 - 4.8e-29 101.3 9.0 7.5e-29 100.7 9.0 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 CEP12631.1 - 0.00057 20.4 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MFS_1 PF07690.16 CEP12632.1 - 2.7e-37 128.5 26.6 3.9e-37 128.0 26.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP12632.1 - 5.3e-11 42.0 15.6 5.3e-11 42.0 15.6 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter DSPc PF00782.20 CEP12633.1 - 0.00023 21.0 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP12633.1 - 0.0037 16.9 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Toxin_29 PF08116.11 CEP12634.1 - 3.4 7.8 11.2 0.63 10.1 5.7 2.2 1 1 1 2 2 2 0 PhTx neurotoxin family DMT_YdcZ PF04657.13 CEP12635.1 - 1.2e-31 109.9 12.9 1.5e-31 109.5 12.9 1.1 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ E1-E2_ATPase PF00122.20 CEP12635.1 - 0.0036 16.9 0.1 0.0036 16.9 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase TctB PF07331.11 CEP12635.1 - 0.062 13.6 12.4 0.081 13.2 12.4 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4149 PF13664.6 CEP12635.1 - 0.76 10.1 7.6 0.61 10.4 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Nucleoporin_N PF08801.11 CEP12636.1 - 0.014 14.1 0.3 0.14 10.9 0.1 2.4 2 0 0 2 2 2 0 Nup133 N terminal like CCDC-167 PF15188.6 CEP12636.1 - 0.25 11.7 4.9 7.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 p450 PF00067.22 CEP12637.1 - 5.2e-86 289.2 0.1 6.7e-86 288.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CEP12638.1 - 1.5e-76 258.0 0.0 2e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ETF PF01012.21 CEP12639.1 - 3.9e-42 144.2 10.0 6.8e-42 143.4 10.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CEP12639.1 - 1.8e-35 120.8 0.6 1.8e-35 120.8 0.6 2.4 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain PG_binding_3 PF09374.10 CEP12639.1 - 0.13 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain NTP_transf_2 PF01909.23 CEP12640.1 - 1.3e-07 31.8 0.0 3.5e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CEP12640.1 - 0.03 14.4 0.2 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase tRNA_NucTransf2 PF09249.11 CEP12640.1 - 0.096 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain ThiF PF00899.21 CEP12642.1 - 1.1e-17 64.2 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CEP12642.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Hexokinase_2 PF03727.16 CEP12643.1 - 1.3e-82 276.9 0.1 1.9e-82 276.3 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP12643.1 - 3.4e-68 229.5 0.0 5.2e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase GDP_Man_Dehyd PF16363.5 CEP12644.1 - 1.3e-56 192.5 0.0 1.5e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP12644.1 - 8.4e-52 176.0 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP12644.1 - 8e-17 61.1 0.0 6.6e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CEP12644.1 - 2.4e-14 53.2 0.1 4.4e-14 52.3 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CEP12644.1 - 2.1e-08 33.6 0.0 3.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CEP12644.1 - 8.5e-08 31.9 0.0 2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP12644.1 - 3.5e-06 27.1 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CEP12644.1 - 4e-06 26.8 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CEP12644.1 - 9e-06 25.0 0.0 0.002 17.3 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 CEP12644.1 - 0.011 15.3 0.8 0.056 13.0 0.6 2.2 2 1 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 CEP12644.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cys_Met_Meta_PP PF01053.20 CEP12644.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IBN_N PF03810.19 CEP12645.1 - 1.1e-12 47.7 1.0 1.1e-10 41.2 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CEP12645.1 - 6.8e-07 28.4 0.0 8.1e-06 24.9 0.0 2.5 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 CEP12645.1 - 2.5e-06 27.6 0.2 2.5e-06 27.6 0.2 4.2 5 2 0 6 6 5 1 Exportin 1-like protein RPOL_N PF14700.6 CEP12645.1 - 0.0006 19.3 1.5 0.00098 18.6 1.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RTP1_C1 PF10363.9 CEP12645.1 - 0.00099 19.3 0.2 0.011 15.9 0.0 2.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 CEP12645.1 - 0.011 15.8 0.5 0.047 13.7 0.2 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP12645.1 - 0.024 14.8 0.1 0.15 12.4 0.1 2.5 1 0 0 1 1 1 0 HEAT repeat DDE_Tnp_IS66_C PF13817.6 CEP12645.1 - 0.028 14.6 0.3 0.39 11.0 0.1 2.5 2 0 0 2 2 2 0 IS66 C-terminal element Paf1 PF03985.13 CEP12645.1 - 0.18 10.8 16.2 0.28 10.1 16.2 1.2 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.10 CEP12645.1 - 0.47 9.7 23.3 0.7 9.2 23.3 1.1 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpc4 PF05132.14 CEP12645.1 - 0.94 9.9 4.4 1.7 9.0 4.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 CEP12645.1 - 1.3 7.1 27.7 2.8 6.0 27.7 1.5 1 0 0 1 1 1 0 Nop14-like family Afi1 PF07792.12 CEP12645.1 - 2.5 8.6 10.9 6.4 7.3 10.9 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TRAP_alpha PF03896.16 CEP12645.1 - 3.4 6.8 12.2 6 6.0 12.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 CEP12645.1 - 4.2 5.3 6.2 7.6 4.5 6.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4746 PF15928.5 CEP12645.1 - 6.8 6.0 18.3 13 5.1 18.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 CEP12645.1 - 9.5 4.9 9.3 16 4.1 9.3 1.2 1 0 0 1 1 1 0 Presenilin Presenilin PF01080.17 CEP12646.1 - 0.81 8.4 37.2 0.034 12.9 21.7 2.1 2 0 0 2 2 2 0 Presenilin Glyco_transf_22 PF03901.17 CEP12647.1 - 5.5e-40 137.9 17.2 8e-40 137.3 17.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 CEP12647.1 - 0.00095 19.4 6.5 0.00095 19.4 6.5 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MASE5 PF17178.4 CEP12647.1 - 0.65 9.8 10.8 0.042 13.7 5.0 1.8 2 0 0 2 2 2 0 Membrane-associated sensor Cullin PF00888.22 CEP12648.1 - 8e-124 414.5 17.9 9.3e-124 414.3 17.9 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEP12648.1 - 7.8e-19 67.5 0.2 3.2e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2779 PF11074.8 CEP12648.1 - 0.041 14.3 0.3 0.041 14.3 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function(DUF2779) Methyltransf_PK PF05891.12 CEP12648.1 - 0.045 13.3 0.1 0.69 9.4 0.0 2.8 3 0 0 3 3 3 0 AdoMet dependent proline di-methyltransferase RVT_1 PF00078.27 CEP12650.1 - 7.7e-24 84.4 0.3 9.4e-23 80.9 0.3 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GPP34 PF05719.11 CEP12651.1 - 6.6e-63 212.4 0.0 8.5e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PMT PF02366.18 CEP12652.1 - 1.8e-44 152.2 12.6 1.8e-44 152.2 12.6 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CEP12652.1 - 7.4e-18 65.1 3.4 1.4e-17 64.2 3.4 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CEP12652.1 - 0.001 19.3 9.3 0.001 19.3 9.3 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEP12652.1 - 0.0024 17.5 3.7 0.0024 17.5 3.7 2.2 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase ERG2_Sigma1R PF04622.12 CEP12653.1 - 1.1e-90 302.5 1.0 1.4e-90 302.3 1.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ECH_2 PF16113.5 CEP12655.1 - 4.9e-128 427.3 0.0 6.4e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEP12655.1 - 5.1e-32 111.2 0.0 2.8e-28 98.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Utp21 PF04192.12 CEP12655.1 - 0.06 12.8 0.6 0.65 9.4 0.1 2.1 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain DUF3621 PF12285.8 CEP12656.1 - 0.16 12.3 2.1 0.61 10.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) N2227 PF07942.12 CEP12657.1 - 1e-106 356.1 0.1 1.3e-106 355.7 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 CEP12657.1 - 0.00017 22.3 0.0 0.0012 19.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 CEP12658.1 - 2.5e-59 195.8 22.0 2e-09 37.9 0.3 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12658.1 - 4.7e-16 58.9 3.4 3.5e-06 27.2 0.2 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP12658.1 - 2.5e-10 39.6 6.7 0.009 14.7 0.0 5.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CEP12658.1 - 1.1e-07 30.9 2.5 0.25 10.0 0.1 4.2 2 1 2 4 4 4 3 Nup133 N terminal like Ge1_WD40 PF16529.5 CEP12658.1 - 2.8e-05 23.3 4.6 0.0041 16.1 0.2 3.0 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEP12658.1 - 0.0011 18.0 1.7 5.8 5.7 0.1 3.3 2 2 1 3 3 3 3 Partner and localizer of BRCA2 WD40 domain LisH PF08513.11 CEP12658.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 LisH gag-asp_proteas PF13975.6 CEP12660.1 - 8.8e-05 23.0 0.0 0.00024 21.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP12660.1 - 0.00015 22.3 0.0 0.00039 21.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 CEP12660.1 - 0.00089 19.5 0.1 0.0032 17.7 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.11 CEP12660.1 - 0.012 15.4 0.2 0.04 13.7 0.2 1.9 1 1 1 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 CEP12661.1 - 3.4e-05 23.5 0.1 6e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BOP1NT PF08145.12 CEP12662.1 - 3.5e-114 381.1 10.0 5.7e-114 380.4 10.0 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CEP12662.1 - 5.4e-25 87.2 9.1 4.6e-07 30.4 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12662.1 - 8e-07 29.3 0.1 0.2 12.0 0.0 5.3 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 CEP12662.1 - 0.16 11.5 0.0 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 IFT57 PF10498.9 CEP12662.1 - 4 6.3 10.1 7.3 5.4 10.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cyclin PF08613.11 CEP12663.1 - 9.7e-11 42.3 0.1 9.7e-11 42.3 0.1 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP12663.1 - 3.6e-06 26.7 0.5 1.1e-05 25.1 0.5 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain PTS_2-RNA PF01885.16 CEP12664.1 - 3.3e-56 190.2 0.1 3.9e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Sigma70_r1_2 PF00140.20 CEP12664.1 - 0.0097 15.9 0.2 0.017 15.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Peptidase_M28 PF04389.17 CEP12665.1 - 4.8e-35 121.0 0.1 1.1e-34 119.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CEP12665.1 - 6.1e-08 32.6 0.1 1.2e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CEP12665.1 - 0.0037 16.8 0.0 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 Nicastrin BRO1 PF03097.18 CEP12666.1 - 1.2e-86 291.0 0.0 1.2e-86 291.0 0.0 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CEP12666.1 - 1e-47 162.8 8.7 1e-47 162.8 8.7 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV HMG_box PF00505.19 CEP12666.1 - 1.9e-34 117.9 13.6 2.1e-20 72.9 1.0 3.5 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP12666.1 - 1.1e-23 83.5 4.3 1.6e-11 44.6 0.8 2.9 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 CEP12666.1 - 0.00049 20.0 1.9 0.002 18.1 0.0 3.1 4 0 0 4 4 4 1 HMG (high mobility group) box 5 DUF4164 PF13747.6 CEP12666.1 - 0.78 10.1 4.9 5 7.5 1.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Pro_isomerase PF00160.21 CEP12667.1 - 1.4e-40 139.2 0.0 2.5e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CEP12667.1 - 1.5e-17 63.1 0.0 3.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RVT PF13966.6 CEP12669.1 - 1.9e-06 28.5 1.2 3.8e-06 27.5 1.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CUE PF02845.16 CEP12670.1 - 8e-10 38.2 0.0 1.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain PTPLA PF04387.14 CEP12671.1 - 1e-50 171.7 15.2 1e-50 171.7 15.2 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA rve PF00665.26 CEP12673.1 - 1.6e-13 50.9 0.0 3.6e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP12673.1 - 5.5e-10 39.2 0.1 1e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP12673.1 - 4.3e-07 30.0 0.8 8.9e-07 29.0 0.8 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Mcm10 PF09332.11 CEP12673.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Mcm10 replication factor rve PF00665.26 CEP12674.1 - 2.4e-07 31.0 0.0 1e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain APG17 PF04108.12 CEP12674.1 - 0.0017 17.5 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 SDH_C PF18317.1 CEP12674.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain RVT_1 PF00078.27 CEP12678.1 - 0.00031 20.3 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G_glu_transpept PF01019.21 CEP12679.1 - 0.24 10.1 0.0 0.26 10.0 0.0 1.0 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase DP-EP PF08985.11 CEP12681.1 - 0.081 13.1 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 DP-EP family zf-CCHC PF00098.23 CEP12682.1 - 0.02 14.9 4.5 0.089 12.9 1.9 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP12682.1 - 0.41 10.4 2.5 0.8 9.5 2.5 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger YL1 PF05764.13 CEP12682.1 - 3.5 7.7 10.7 5.6 7.0 10.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CEP12682.1 - 6.7 4.8 11.9 9.3 4.3 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family rve PF00665.26 CEP12683.1 - 2e-09 37.6 0.0 8.5e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-C2H2_10 PF16588.5 CEP12684.1 - 0.012 15.4 7.7 0.018 14.8 4.1 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 CEP12684.1 - 0.013 15.6 9.7 0.85 9.8 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEP12684.1 - 4.7 7.1 19.2 1.3 8.9 7.3 2.6 3 0 0 3 3 3 0 Zinc knuckle DDE_3 PF13358.6 CEP12687.1 - 4.7e-07 29.7 0.0 9.8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.27 CEP12688.1 - 0.037 13.5 0.2 0.15 11.6 0.2 2.0 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3319 PF11782.8 CEP12688.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) HAD_2 PF13419.6 CEP12688.1 - 0.12 12.5 0.0 0.63 10.1 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Retrotrans_gag PF03732.17 CEP12689.1 - 0.00063 20.0 0.9 0.0026 18.0 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP12690.1 - 3.4e-11 43.6 0.1 5.3e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP12690.1 - 2.4e-09 37.7 0.1 3.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP12690.1 - 1.8e-08 34.2 0.0 2.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CEP12690.1 - 0.00095 19.4 0.1 0.0018 18.5 0.1 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP12690.1 - 0.0081 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 CEP12690.1 - 0.016 15.0 0.1 0.068 12.9 0.0 1.9 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Band_3_cyto PF07565.13 CEP12691.1 - 0.41 10.4 3.4 0.46 10.2 3.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 CEP12691.1 - 1.2 9.2 3.1 1.4 8.9 3.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NDC10_II PF16787.5 CEP12692.1 - 3.5e-16 59.2 0.2 4.3e-16 58.9 0.2 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 NDC10_II PF16787.5 CEP12693.1 - 1.3e-26 93.4 0.0 2.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP12693.1 - 1.4e-16 60.6 1.0 1.7e-16 60.3 0.1 1.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes RVP_2 PF08284.11 CEP12695.1 - 0.02 14.7 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_3 PF13917.6 CEP12695.1 - 0.026 14.5 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CEP12695.1 - 0.04 14.0 2.0 0.064 13.4 2.0 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4187 PF13821.6 CEP12695.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) RVT_1 PF00078.27 CEP12696.1 - 1.3e-17 64.0 0.1 2.7e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prenyltrans PF00432.21 CEP12697.1 - 5.9e-40 134.7 16.6 3.4e-09 36.3 0.0 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat IPP-2 PF04979.14 CEP12697.1 - 1.9e-17 64.2 9.0 3.5e-17 63.4 9.0 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) SQHop_cyclase_C PF13243.6 CEP12697.1 - 0.00016 20.9 0.0 1.5 7.8 0.0 3.2 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CEP12697.1 - 0.0015 17.7 0.1 1.5 7.8 0.1 3.0 1 1 2 3 3 3 3 Squalene-hopene cyclase N-terminal domain CAF1C_H4-bd PF12265.8 CEP12698.1 - 7.3e-30 103.0 0.6 1.9e-29 101.7 0.6 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CEP12698.1 - 2e-24 85.4 13.1 1.6e-05 25.6 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12698.1 - 0.00064 20.0 3.3 0.74 10.2 0.2 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Jak1_Phl PF17887.1 CEP12700.1 - 0.0037 17.2 1.7 0.0097 15.9 1.7 1.7 1 0 0 1 1 1 1 Jak1 pleckstrin homology-like domain Ecl1 PF12855.7 CEP12701.1 - 4.4e-10 41.0 16.4 8.9e-10 40.0 16.4 1.6 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CEP12701.1 - 0.0027 17.8 0.3 0.0071 16.4 0.3 1.7 1 0 0 1 1 1 1 MYND finger VATC PF18716.1 CEP12701.1 - 0.37 10.7 4.7 3.1 7.7 3.5 2.6 2 1 0 2 2 2 0 Vms1-associating treble clef domain ANF_receptor PF01094.28 CEP12702.1 - 2.9e-32 112.2 7.0 3.7e-32 111.8 7.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CEP12702.1 - 1.3e-18 67.6 13.0 3.5e-18 66.2 13.0 1.8 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 CEP12702.1 - 1.2e-07 31.8 0.6 2.9e-07 30.5 0.6 1.6 1 1 0 1 1 1 1 Periplasmic binding protein Acyl_transf_1 PF00698.21 CEP12703.1 - 2.1e-26 93.2 0.8 3.5e-26 92.5 0.8 1.3 1 0 0 1 1 1 1 Acyl transferase domain S4 PF01479.25 CEP12703.1 - 2.9e-11 42.9 0.0 6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CEP12703.1 - 1.6e-09 38.5 3.3 3.9e-09 37.3 3.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4254 PF14063.6 CEP12703.1 - 1.1 9.1 3.9 6.3 6.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) UvdE PF03851.14 CEP12704.1 - 1.3e-10 41.0 0.4 3.1e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 UV-endonuclease UvdE UvdE PF03851.14 CEP12705.1 - 1.5e-78 263.8 0.2 1.5e-78 263.8 0.2 2.3 2 1 0 2 2 2 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 CEP12705.1 - 0.00084 18.8 0.1 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel NAD_binding_1 PF00175.21 CEP12705.1 - 0.52 11.0 4.6 0.85 10.3 3.3 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF1484 PF07363.11 CEP12705.1 - 0.67 11.0 4.3 2.1 9.4 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) ApoO PF09769.9 CEP12705.1 - 0.82 9.6 5.4 1.7 8.6 5.4 1.7 1 1 0 1 1 1 0 Apolipoprotein O YlbD_coat PF14071.6 CEP12705.1 - 4.1 7.7 12.1 47 4.3 12.1 2.6 1 1 0 1 1 1 0 Putative coat protein CALCOCO1 PF07888.11 CEP12706.1 - 8.3e-05 21.6 38.3 0.0034 16.3 12.2 2.6 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 CEP12706.1 - 0.002 18.6 48.6 0.0054 17.3 15.5 3.4 1 1 2 3 3 3 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CEP12706.1 - 0.0023 18.0 35.5 0.22 11.5 7.1 3.7 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CEP12706.1 - 0.0033 17.5 11.2 0.11 12.6 0.4 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) YabA PF06156.13 CEP12706.1 - 0.0067 17.0 21.2 0.35 11.5 1.6 3.9 1 1 2 3 3 3 1 Initiation control protein YabA DUF2968 PF11180.8 CEP12706.1 - 0.0082 15.8 15.0 0.37 10.4 0.9 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF2968) Effector_1 PF04518.12 CEP12706.1 - 0.0091 15.1 1.3 0.0091 15.1 1.3 1.5 1 1 0 1 1 1 1 Effector from type III secretion system DUF3450 PF11932.8 CEP12706.1 - 0.022 14.0 22.3 0.031 13.6 2.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) AAA_13 PF13166.6 CEP12706.1 - 0.087 11.4 14.8 0.12 11.0 14.8 1.3 1 0 0 1 1 1 0 AAA domain ERM PF00769.19 CEP12706.1 - 0.28 11.0 38.1 1.6 8.5 12.7 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FapA PF03961.13 CEP12706.1 - 0.38 9.3 19.3 0.78 8.3 4.3 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A Spc7 PF08317.11 CEP12706.1 - 0.43 9.4 30.4 0.26 10.1 14.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 CEP12706.1 - 0.71 10.4 36.3 0.58 10.6 3.8 4.2 1 1 2 4 4 4 0 Cell division protein ZapB DUF3287 PF11690.8 CEP12706.1 - 0.79 9.5 8.8 7 6.4 0.0 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) Atg14 PF10186.9 CEP12706.1 - 1 8.3 15.9 1.3 8.0 4.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 CEP12706.1 - 1.1 9.5 24.4 0.056 13.7 1.9 3.8 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain ORF6C PF10552.9 CEP12706.1 - 1.2 9.2 6.1 6.3 6.9 0.6 2.8 2 0 0 2 2 2 0 ORF6C domain Sec34 PF04136.15 CEP12706.1 - 1.4 8.8 15.3 5.9 6.8 1.0 3.7 1 1 4 5 5 5 0 Sec34-like family Syntaxin-6_N PF09177.11 CEP12706.1 - 1.5 9.4 21.4 15 6.2 5.7 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 CEP12706.1 - 2 8.6 42.5 0.11 12.7 28.1 3.1 1 1 1 2 2 2 0 Tropomyosin like TMPIT PF07851.13 CEP12706.1 - 2.6 7.2 18.4 2.7 7.1 2.6 3.0 1 1 2 3 3 3 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 CEP12706.1 - 2.8 8.0 36.9 1.2 9.2 17.1 4.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 CEP12706.1 - 3.5 7.8 31.3 0.35 11.1 13.7 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 CEP12706.1 - 6.9 6.9 36.5 0.53 10.5 0.5 5.2 2 1 2 5 5 5 0 JNK-interacting protein leucine zipper II KELK PF15796.5 CEP12706.1 - 9.4 6.8 31.9 2.6 8.6 2.7 4.0 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_12 PF13087.6 CEP12707.1 - 1.3e-57 194.7 0.0 2.1e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP12707.1 - 6.5e-40 137.6 1.5 1.4e-38 133.2 0.4 2.9 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CEP12707.1 - 7e-08 32.5 0.0 0.0047 16.7 0.0 2.7 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CEP12707.1 - 4.1e-06 26.6 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 CEP12707.1 - 0.0039 17.0 0.6 0.047 13.5 0.0 2.7 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 CEP12707.1 - 0.026 13.9 0.2 0.17 11.2 0.0 2.1 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.7 CEP12707.1 - 0.028 14.0 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2300 PF10062.9 CEP12708.1 - 0.24 11.5 3.2 0.68 10.0 0.8 2.2 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) Inhibitor_I36 PF03995.13 CEP12708.1 - 0.59 10.1 3.4 0.66 9.9 0.7 2.4 2 0 0 2 2 2 0 Peptidase inhibitor family I36 zf-RING_14 PF17978.1 CEP12709.1 - 3.7 8.0 8.9 13 6.3 1.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Oxidored_molyb PF00174.19 CEP12711.1 - 5.1e-47 159.7 0.0 1.1e-46 158.6 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CEP12711.1 - 1.3e-29 103.0 1.8 2.1e-29 102.3 1.8 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain ABC2_membrane PF01061.24 CEP12712.1 - 9.5e-84 280.0 63.9 2.2e-44 151.4 24.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CEP12712.1 - 7.7e-35 120.4 0.0 1.8e-18 67.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEP12712.1 - 4.8e-28 96.9 0.0 6.7e-21 74.0 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP12712.1 - 7.1e-12 45.8 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CEP12712.1 - 7e-10 38.5 48.7 5.2e-07 29.1 18.7 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CEP12712.1 - 4.9e-05 23.3 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEP12712.1 - 5.3e-05 23.7 0.0 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEP12712.1 - 6.4e-05 22.9 0.2 0.0028 17.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CEP12712.1 - 0.0026 17.5 0.2 0.014 15.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CEP12712.1 - 0.0028 17.3 0.1 0.0092 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP12712.1 - 0.023 14.8 0.0 0.71 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEP12712.1 - 0.066 13.8 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEP12712.1 - 0.067 13.5 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEP12712.1 - 0.094 12.4 0.3 2 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CEP12712.1 - 0.095 12.0 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 CEP12712.1 - 0.19 12.2 0.6 0.59 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CEP12712.1 - 0.32 11.0 0.9 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SCA7 PF08313.12 CEP12714.1 - 2.6e-28 97.7 0.2 1.2e-27 95.6 0.2 2.1 1 1 0 1 1 1 1 SCA7, zinc-binding domain GATA PF00320.27 CEP12715.1 - 4.9e-16 58.0 3.2 1.2e-15 56.8 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Focal_AT PF03623.13 CEP12715.1 - 0.035 14.1 0.5 0.065 13.2 0.5 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region G-patch PF01585.23 CEP12716.1 - 1.4e-13 50.5 1.0 2.5e-13 49.7 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP12716.1 - 8.1e-05 22.6 0.2 8.1e-05 22.6 0.2 2.1 3 0 0 3 3 3 1 G-patch domain KDZ PF18758.1 CEP12717.1 - 5.8e-07 29.3 0.0 6.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP12717.1 - 0.00058 20.0 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases zf-met PF12874.7 CEP12718.1 - 0.0013 19.0 0.4 0.025 15.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF629 PF04780.12 CEP12718.1 - 0.028 13.0 0.3 0.15 10.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 CEP12718.1 - 0.058 14.3 3.6 0.14 13.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CUE PF02845.16 CEP12719.1 - 1.2e-06 28.1 0.2 2.1e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 CEP12719.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif FUN14 PF04930.15 CEP12720.1 - 2.1e-25 88.9 2.2 4e-25 88.0 2.2 1.5 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 CEP12720.1 - 0.0086 15.5 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CEP12720.1 - 0.049 13.2 0.3 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 CEP12720.1 - 0.052 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_7 PF13499.6 CEP12720.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 CEP12720.1 - 0.11 12.4 0.3 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Pneumo_att_G PF05539.11 CEP12721.1 - 3.4 7.1 7.5 2.1 7.9 6.0 1.4 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DEAD PF00270.29 CEP12723.1 - 3.9e-38 131.0 0.0 7.9e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP12723.1 - 1.2e-28 99.6 0.2 1.6e-26 92.8 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP12723.1 - 1.3e-06 28.5 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEP12723.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Clusterin PF01093.17 CEP12723.1 - 0.069 12.2 3.4 0.52 9.3 0.2 2.2 1 1 1 2 2 2 0 Clusterin DAO PF01266.24 CEP12724.1 - 9.4e-38 130.7 0.0 1.1e-37 130.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP12724.1 - 9.9e-05 21.6 0.0 0.00028 20.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CEP12724.1 - 0.024 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP12724.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CEP12724.1 - 0.047 13.8 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 CEP12724.1 - 0.091 13.0 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP12724.1 - 0.097 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CEP12724.1 - 0.098 13.2 0.2 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trehalase PF01204.18 CEP12725.1 - 1.1e-180 601.9 3.0 1.3e-180 601.6 3.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CEP12725.1 - 3.3e-15 55.5 1.4 6e-15 54.7 1.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RPAP3_C PF13877.6 CEP12726.1 - 4.1e-22 78.5 0.0 8.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 CEP12726.1 - 7.9e-14 50.6 0.3 3.4e-06 26.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP12726.1 - 2.5e-13 49.2 0.3 9e-05 22.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP12726.1 - 4.8e-11 42.2 0.5 0.00031 20.3 0.2 3.3 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 CEP12726.1 - 1.8e-10 40.2 0.0 0.00018 21.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEP12726.1 - 4.6e-05 23.5 0.0 0.00017 21.7 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP12726.1 - 0.00013 22.5 0.0 0.0095 16.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP12726.1 - 0.00028 21.1 0.1 0.34 11.4 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP12726.1 - 0.0043 17.6 1.1 1.2 10.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP12726.1 - 0.0099 16.4 0.1 0.25 11.9 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP12726.1 - 0.013 16.1 0.0 0.36 11.5 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Erf4 PF10256.9 CEP12726.1 - 0.015 15.4 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TPR_10 PF13374.6 CEP12726.1 - 0.04 13.8 0.2 0.61 10.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP12726.1 - 0.073 13.4 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat T3SS_ExsE PF18286.1 CEP12726.1 - 0.15 12.0 0.2 0.45 10.5 0.2 1.8 1 1 0 1 1 1 0 Type III secretion system ExsE DDE_3 PF13358.6 CEP12727.1 - 3.3e-14 52.9 0.0 5.7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MPP6 PF10175.9 CEP12731.1 - 0.005 17.3 12.5 0.0091 16.5 5.7 2.1 2 0 0 2 2 2 2 M-phase phosphoprotein 6 NOA36 PF06524.12 CEP12731.1 - 2.1 7.6 11.3 4.3 6.6 11.3 1.6 1 0 0 1 1 1 0 NOA36 protein FUSC_2 PF13515.6 CEP12732.1 - 8.8e-19 67.9 7.8 8.8e-19 67.9 7.8 3.2 2 1 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEP12732.1 - 1.5e-11 43.7 3.8 1.5e-11 43.7 3.8 3.2 3 1 1 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.8 CEP12732.1 - 5.1e-10 38.8 4.7 5.1e-10 38.8 4.7 3.3 2 1 0 3 3 3 2 Aluminium activated malate transporter ArAE_2 PF10334.9 CEP12732.1 - 1.3e-09 38.3 0.2 3.8e-09 36.7 0.2 1.9 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CEP12732.1 - 0.00023 20.4 0.3 0.00023 20.4 0.3 2.2 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_1 PF06081.11 CEP12732.1 - 0.0086 16.2 4.9 0.027 14.6 4.9 1.9 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 Tat PF00539.18 CEP12732.1 - 0.065 13.4 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) SHR3_chaperone PF08229.11 CEP12733.1 - 1.6e-22 79.4 0.4 6.4e-11 41.6 0.3 2.0 1 1 1 2 2 2 2 ER membrane protein SH3 Glt_symporter PF03616.14 CEP12733.1 - 0.0072 15.1 0.1 0.0087 14.8 0.1 1.1 1 0 0 1 1 1 1 Sodium/glutamate symporter DUF3169 PF11368.8 CEP12733.1 - 0.011 15.3 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Radial_spoke PF04712.12 CEP12733.1 - 0.014 14.4 0.1 0.015 14.3 0.1 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4632 PF15451.6 CEP12733.1 - 2.6 8.2 6.1 4.7 7.3 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) HABP4_PAI-RBP1 PF04774.15 CEP12735.1 - 0.0018 19.1 0.2 0.0022 18.8 0.2 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Aa_trans PF01490.18 CEP12736.1 - 1.2e-37 129.6 23.3 2.8e-26 92.2 11.0 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Spore_permease PF03845.13 CEP12736.1 - 0.025 13.4 16.8 0.015 14.1 8.3 2.2 2 0 0 2 2 2 0 Spore germination protein HABP4_PAI-RBP1 PF04774.15 CEP12736.1 - 0.032 15.1 0.1 0.058 14.2 0.1 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family YL1 PF05764.13 CEP12738.1 - 0.035 14.2 8.7 0.05 13.7 8.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Tim54 PF11711.8 CEP12738.1 - 0.14 10.9 2.1 0.22 10.3 2.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1387 PF07139.11 CEP12738.1 - 0.46 10.2 7.1 0.72 9.5 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Nop14 PF04147.12 CEP12738.1 - 0.82 7.8 15.8 1.1 7.3 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CEP12738.1 - 1.2 8.5 11.8 1.6 8.1 11.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CEP12738.1 - 1.2 7.1 14.8 1.8 6.6 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 CEP12738.1 - 1.9 8.1 17.7 3.2 7.4 17.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 CEP12738.1 - 2.8 7.6 5.9 5.3 6.7 5.9 1.4 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 CEP12738.1 - 2.9 7.6 13.0 4.3 7.0 13.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CEP12738.1 - 3 6.0 9.6 4 5.6 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CEP12738.1 - 4.6 6.5 13.4 6.7 5.9 13.4 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 CEP12738.1 - 6 4.8 12.9 9.4 4.2 12.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spectrin_like PF18373.1 CEP12739.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Spectrin like domain MULE PF10551.9 CEP12740.1 - 1.1e-08 35.4 0.6 3.5e-08 33.8 0.6 2.0 1 0 0 1 1 1 1 MULE transposase domain ALS2CR8 PF15299.6 CEP12740.1 - 0.00021 21.2 0.9 0.00021 21.2 0.9 2.0 2 1 0 2 2 2 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 FAR1 PF03101.15 CEP12740.1 - 0.0057 17.3 0.1 0.017 15.8 0.1 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain DDE_Tnp_ISL3 PF01610.17 CEP12740.1 - 0.0082 15.9 2.2 0.0092 15.7 0.2 2.1 2 1 0 2 2 2 1 Transposase CRAL_TRIO PF00650.20 CEP12740.1 - 0.048 13.4 1.4 0.25 11.0 0.2 2.4 2 0 0 2 2 2 0 CRAL/TRIO domain Filamin PF00630.19 CEP12740.1 - 0.082 13.7 0.2 2.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Filamin/ABP280 repeat Sde2_N_Ubi PF13019.6 CEP12741.1 - 1.5e-34 119.2 0.7 4.1e-34 117.8 0.7 1.8 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain ubiquitin PF00240.23 CEP12741.1 - 0.00012 21.8 2.2 0.00044 19.9 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 CEP12741.1 - 0.065 13.8 6.0 2.5 8.7 0.0 3.3 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain CRAL_TRIO PF00650.20 CEP12743.1 - 7.4e-21 74.5 0.4 5.5e-19 68.4 0.1 2.3 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP12743.1 - 1.4e-12 47.6 0.1 3.6e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CEP12743.1 - 0.056 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3198 PF11433.8 CEP12743.1 - 0.21 11.5 3.7 2.7 7.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) SPX PF03105.19 CEP12744.1 - 5.2e-39 135.2 14.7 3.5e-25 89.7 11.0 2.6 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 CEP12744.1 - 1.1e-31 110.5 33.6 1.5e-31 110.0 33.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CEP12744.1 - 3.3e-20 72.5 40.9 1.5e-15 57.2 13.9 2.4 1 1 1 2 2 2 2 Citrate transporter HicA_toxin PF07927.12 CEP12744.1 - 0.11 12.5 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Siah-Interact_N PF09032.11 CEP12744.1 - 0.29 11.5 1.1 0.63 10.4 1.1 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal AIG1 PF04548.16 CEP12745.1 - 1.2e-20 73.7 0.7 5.9e-20 71.5 0.6 2.1 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 CEP12745.1 - 1.4e-10 41.2 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CEP12745.1 - 2.7e-07 30.8 0.4 0.012 15.6 0.2 2.4 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 CEP12745.1 - 0.001 19.0 0.3 0.0037 17.2 0.3 1.9 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 CEP12745.1 - 0.0011 19.4 0.1 0.003 18.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter GBP PF02263.19 CEP12745.1 - 0.0075 15.6 0.1 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain AAA_23 PF13476.6 CEP12745.1 - 0.017 15.6 0.3 0.026 15.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CEP12745.1 - 0.085 12.4 0.7 0.24 10.9 0.7 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B RVT_1 PF00078.27 CEP12746.1 - 8.7e-31 107.2 0.1 2.6e-30 105.6 0.0 1.7 1 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.29 CEP12747.1 - 0.041 14.4 2.8 1.2 9.7 0.0 3.6 4 0 0 4 4 4 0 PH domain Peptidase_S24 PF00717.23 CEP12748.1 - 6.6e-10 38.8 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Vac7 PF12751.7 CEP12749.1 - 3.9e-22 79.2 8.5 2.5e-17 63.4 0.0 2.6 1 1 1 2 2 2 2 Vacuolar segregation subunit 7 ADH_N PF08240.12 CEP12750.1 - 1.6e-25 89.1 4.8 2.5e-25 88.5 4.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP12750.1 - 5.6e-13 49.0 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEP12750.1 - 0.0074 15.7 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-synt_D PF01813.17 CEP12751.1 - 2.9e-73 245.9 5.1 3.7e-73 245.6 5.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D TACC_C PF05010.14 CEP12751.1 - 0.25 11.1 7.2 0.79 9.5 1.2 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Allexi_40kDa PF05549.11 CEP12751.1 - 0.5 9.8 2.3 3.5 7.0 0.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 CEP12751.1 - 2.2 8.3 7.6 0.54 10.3 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Gly-zipper_Omp PF13488.6 CEP12752.1 - 0.0041 17.1 1.7 0.0066 16.4 1.7 1.2 1 0 0 1 1 1 1 Glycine zipper MGC-24 PF05283.11 CEP12752.1 - 0.0065 16.9 1.2 0.0065 16.9 1.2 2.2 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TRAP_alpha PF03896.16 CEP12752.1 - 0.011 15.0 1.9 0.019 14.2 1.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rick_17kDa_Anti PF05433.15 CEP12752.1 - 0.072 13.0 7.2 0.12 12.3 7.2 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain Beta-APP PF03494.13 CEP12752.1 - 0.14 12.0 2.6 0.25 11.2 2.6 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Nop14 PF04147.12 CEP12752.1 - 0.29 9.3 2.4 0.35 9.0 2.4 1.1 1 0 0 1 1 1 0 Nop14-like family Podoplanin PF05808.11 CEP12752.1 - 0.3 11.2 12.1 1.3 9.1 12.1 2.0 1 1 0 1 1 1 0 Podoplanin RRN3 PF05327.11 CEP12752.1 - 0.75 8.3 2.3 0.9 8.0 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CEP12752.1 - 1 7.4 8.8 0.36 8.9 5.8 1.6 2 0 0 2 2 2 0 DNA polymerase phi Roughex PF06020.11 CEP12752.1 - 8.6 5.3 10.8 14 4.6 10.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Tetraspanin PF00335.20 CEP12753.1 - 1.9e-05 24.5 9.6 1.9e-05 24.5 9.6 2.1 1 1 2 3 3 3 1 Tetraspanin family SelK_SelG PF10961.8 CEP12753.1 - 0.18 12.4 3.8 7.7 7.2 0.5 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PKD_channel PF08016.12 CEP12753.1 - 0.46 9.1 12.5 0.96 8.1 11.9 1.6 1 1 1 2 2 2 0 Polycystin cation channel DUF2754 PF10953.8 CEP12753.1 - 1.3 9.3 6.5 1.2 9.5 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) DUF805 PF05656.14 CEP12753.1 - 8 6.9 12.2 1.6e+02 2.7 12.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) RPN6_N PF18055.1 CEP12754.1 - 2e-39 134.5 1.5 2e-39 134.5 1.5 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CEP12754.1 - 1.8e-19 70.2 3.9 2.5e-19 69.7 0.1 3.0 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CEP12754.1 - 1.8e-11 43.6 1.5 5.1e-11 42.1 1.5 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 CEP12754.1 - 0.0014 18.5 5.3 4.2 7.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat DDRGK PF09756.9 CEP12754.1 - 0.12 12.0 0.1 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 DDRGK domain RPN7 PF10602.9 CEP12755.1 - 8e-60 201.5 1.3 1.3e-59 200.8 1.3 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CEP12755.1 - 2e-13 50.8 0.5 7.3e-13 48.9 0.1 2.2 3 0 0 3 3 3 1 PCI domain HTH_DeoR PF08220.12 CEP12755.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TPR_2 PF07719.17 CEP12755.1 - 0.052 13.7 0.8 0.51 10.6 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF357 PF04010.13 CEP12755.1 - 0.054 13.6 1.9 0.15 12.1 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF357) SpoIIID PF12116.8 CEP12755.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D TPR_6 PF13174.6 CEP12755.1 - 0.17 12.6 2.4 0.55 11.0 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP12755.1 - 0.56 10.5 5.4 0.17 12.2 1.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3656 PF12392.8 CEP12756.1 - 0.047 14.3 0.3 0.088 13.5 0.3 1.4 1 0 0 1 1 1 0 Collagenase LOH1CR12 PF10158.9 CEP12756.1 - 0.19 11.8 4.2 0.42 10.6 4.2 1.6 1 0 0 1 1 1 0 Tumour suppressor protein zf-C3HC4_3 PF13920.6 CEP12757.1 - 3.4e-05 23.6 7.9 3.4e-05 23.6 7.9 3.9 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CEP12757.1 - 0.014 15.8 0.2 0.014 15.8 0.2 6.9 8 2 0 8 8 8 0 Zinc finger, C2H2 type YEATS PF03366.16 CEP12758.1 - 8.6e-17 60.9 0.2 1.8e-16 59.9 0.2 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CEP12758.1 - 0.27 11.4 2.2 4.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Nup88 PF10168.9 CEP12759.1 - 0.00016 19.7 16.9 0.0002 19.4 16.9 1.1 1 0 0 1 1 1 1 Nuclear pore component Spc7 PF08317.11 CEP12759.1 - 0.0087 15.0 2.8 0.0087 15.0 2.8 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein DELLA PF12041.8 CEP12759.1 - 0.019 14.9 0.1 0.087 12.7 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal DUF1993 PF09351.10 CEP12759.1 - 0.026 14.7 7.9 0.018 15.2 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Cyclase_polyket PF04673.12 CEP12759.1 - 0.034 14.4 0.2 0.078 13.2 0.2 1.7 1 0 0 1 1 1 0 Polyketide synthesis cyclase Baculo_PEP_C PF04513.12 CEP12759.1 - 0.07 13.2 1.9 18 5.4 0.0 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AvrM_N PF18247.1 CEP12759.1 - 0.085 12.8 0.7 0.36 10.8 0.0 2.4 2 1 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain ADIP PF11559.8 CEP12759.1 - 0.67 10.0 20.2 1.4 9.0 0.1 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DotD PF16816.5 CEP12759.1 - 0.68 9.9 4.2 1.4 8.9 1.7 2.7 2 1 0 2 2 2 0 DotD protein Transglut_i_TM PF14400.6 CEP12759.1 - 0.73 9.9 5.5 19 5.3 5.3 2.3 1 1 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices FCH PF00611.23 CEP12759.1 - 1.2 9.4 7.9 0.62 10.4 1.6 2.8 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 CEP12759.1 - 1.2 9.4 17.1 0.1 12.9 10.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CEP12759.1 - 1.5 8.1 11.4 1.5 8.1 10.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Wbp11 PF09429.10 CEP12759.1 - 2.4 8.6 21.3 0.75 10.2 1.3 3.7 3 1 0 3 3 3 0 WW domain binding protein 11 Elongin_A PF06881.11 CEP12759.1 - 4.5 7.9 10.8 0.94 10.0 5.3 2.5 1 1 2 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Nup88 PF10168.9 CEP12760.1 - 1.1e-22 79.7 0.1 3.2e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore component Bestrophin PF01062.21 CEP12762.1 - 1.8e-53 181.9 0.0 1.4e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel HBD PF18534.1 CEP12762.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Helical bundle domain DUF4239 PF14023.6 CEP12762.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) ApbA PF02558.16 CEP12763.1 - 2.8e-17 62.8 0.0 3.9e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CEP12763.1 - 1.5e-06 28.4 0.1 3.4e-06 27.3 0.1 1.6 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal FR47 PF08445.10 CEP12764.1 - 1.3e-08 34.7 0.0 1.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 CEP12764.1 - 0.00034 20.8 0.0 0.00096 19.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP12764.1 - 0.00042 20.7 0.0 0.00084 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DnaJ_C PF01556.18 CEP12765.1 - 6.1e-43 146.5 0.3 7.8e-43 146.1 0.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP12765.1 - 9.6e-27 92.9 1.0 1.8e-26 92.1 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP12765.1 - 7.7e-15 55.0 20.6 1.3e-14 54.3 20.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEP12765.1 - 0.01 15.7 0.5 0.01 15.7 0.5 2.9 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEP12765.1 - 2.1 8.4 14.7 1.6 8.8 2.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SBF PF01758.16 CEP12766.1 - 8.3e-54 182.2 10.4 8.3e-54 182.2 10.4 2.3 3 0 0 3 3 3 1 Sodium Bile acid symporter family RRM_1 PF00076.22 CEP12767.1 - 2.4e-19 68.9 0.1 3.4e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP12767.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEP12767.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Hepatitis_core PF00906.20 CEP12767.1 - 4.5 6.8 9.6 11 5.4 9.6 1.6 1 0 0 1 1 1 0 Hepatitis core antigen Astro_capsid_p PF12226.8 CEP12768.1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ADH_N PF08240.12 CEP12769.1 - 1.1e-30 105.7 1.4 1.1e-30 105.7 1.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP12769.1 - 3.6e-22 78.7 0.4 5.3e-22 78.2 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEP12769.1 - 1.3e-08 34.6 2.1 2.4e-07 30.5 2.1 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CEP12769.1 - 6.8e-05 22.3 1.2 0.00033 20.0 1.2 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CEP12769.1 - 0.00029 21.9 0.0 0.0005 21.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 CEP12769.1 - 0.0019 18.9 0.0 0.0047 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF1647 PF07801.11 CEP12769.1 - 0.0062 16.3 0.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1647) UDPG_MGDP_dh_N PF03721.14 CEP12769.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.14 CEP12769.1 - 0.0073 15.9 0.1 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain 3HCDH_N PF02737.18 CEP12769.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CEP12769.1 - 0.035 13.3 0.8 0.12 11.6 0.2 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TP_methylase PF00590.20 CEP12769.1 - 0.065 13.2 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_synthase PF02540.17 CEP12770.1 - 6.7e-23 81.0 0.0 1.4e-22 80.0 0.0 1.4 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 CEP12770.1 - 4.1e-21 75.5 0.0 5.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.21 CEP12770.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Pkinase PF00069.25 CEP12771.1 - 7.3e-68 228.8 0.0 9.2e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12771.1 - 1.4e-34 119.6 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP12771.1 - 1.9e-08 34.0 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP12771.1 - 0.0012 17.9 0.1 0.0023 16.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP12771.1 - 0.0054 16.1 0.1 0.0081 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP12771.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP12771.1 - 0.033 13.0 1.3 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CEP12771.1 - 0.044 12.8 0.1 0.1 11.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CEP12771.1 - 0.051 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 KH_1 PF00013.29 CEP12772.1 - 1.5e-26 92.0 0.0 1.6e-08 34.2 0.0 7.0 7 0 0 7 7 7 6 KH domain Melibiase PF02065.18 CEP12773.1 - 4.9e-101 338.1 0.0 6.3e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 CEP12773.1 - 2.4e-52 178.0 0.0 3.3e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 CEP12773.1 - 2.2e-11 44.1 0.0 4.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 CEP12773.1 - 1e-06 28.1 0.1 1.9e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_31 PF01055.26 CEP12773.1 - 7.8e-05 22.0 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 CEP12773.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Gti1_Pac2 PF09729.9 CEP12774.1 - 1.9e-31 109.6 0.0 1.9e-31 109.6 0.0 3.2 2 1 0 2 2 2 1 Gti1/Pac2 family SUIM_assoc PF16619.5 CEP12774.1 - 0.0046 17.0 6.7 0.51 10.4 0.2 4.0 3 2 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 PIF1 PF05970.14 CEP12775.1 - 1.6e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP12775.1 - 1.6e-08 34.5 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP12775.1 - 0.0027 18.0 0.0 0.0038 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HTH_psq PF05225.16 CEP12779.1 - 1.1e-07 31.5 0.0 5.6e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP12779.1 - 4.7e-06 26.6 0.8 6.9e-06 26.1 0.8 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CEP12779.1 - 3.7e-05 23.3 0.0 7.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CEP12779.1 - 0.0012 18.5 0.2 0.002 17.9 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain UPF0175 PF03683.13 CEP12779.1 - 0.004 16.8 0.0 0.016 14.9 0.0 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0175) HTH_29 PF13551.6 CEP12779.1 - 0.0063 16.5 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix FeoC PF09012.10 CEP12779.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator Sigma70_r4 PF04545.16 CEP12779.1 - 0.018 14.5 0.2 0.037 13.5 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 GntR PF00392.21 CEP12779.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_3 PF01381.22 CEP12779.1 - 0.021 14.9 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Phage_NinH PF06322.11 CEP12779.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein HTH_17 PF12728.7 CEP12779.1 - 0.031 14.5 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.18 CEP12779.1 - 0.064 13.2 0.1 0.087 12.8 0.1 1.3 1 1 0 1 1 1 0 'Paired box' domain HTH_Tnp_ISL3 PF13542.6 CEP12779.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GCP_C_terminal PF04130.13 CEP12780.1 - 7.5e-55 186.6 13.4 7.5e-55 186.6 13.4 2.7 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CEP12780.1 - 2.9e-24 86.3 0.7 9.4e-24 84.6 0.7 1.9 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal N6_N4_Mtase PF01555.18 CEP12780.1 - 0.06 13.0 0.3 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 DNA methylase Gemini_AL1 PF00799.20 CEP12780.1 - 0.27 11.6 2.2 1.4 9.3 0.4 2.9 1 1 1 2 2 2 0 Geminivirus Rep catalytic domain Pro_dh PF01619.18 CEP12781.1 - 9.4e-73 245.3 0.6 6.1e-72 242.6 0.6 2.0 1 1 0 1 1 1 1 Proline dehydrogenase DUF3270 PF11674.8 CEP12783.1 - 0.051 13.8 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Beta-Casp PF10996.8 CEP12784.1 - 2.7e-27 95.2 0.0 1.5e-25 89.6 0.0 2.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CEP12784.1 - 3e-22 79.0 0.0 5.3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CEP12784.1 - 1.3e-17 63.5 0.0 2.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CEP12784.1 - 1.3e-11 44.9 0.1 1.7e-10 41.3 0.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP12784.1 - 3.5e-11 43.0 0.2 6.4e-10 38.9 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP12784.1 - 0.00016 21.6 0.0 0.00064 19.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TIP120 PF08623.10 CEP12785.1 - 6.8e-64 214.7 8.7 4.7e-63 211.9 0.1 4.9 3 2 2 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 CEP12785.1 - 1.1e-13 51.3 15.6 0.049 14.1 0.0 11.4 10 2 2 12 12 11 3 HEAT-like repeat HEAT PF02985.22 CEP12785.1 - 7.1e-13 47.6 19.4 1.6 9.2 0.1 12.6 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 CEP12785.1 - 6.2e-12 45.7 12.6 0.0062 16.9 0.1 8.7 7 1 3 10 10 9 3 HEAT repeats CLASP_N PF12348.8 CEP12785.1 - 3e-06 27.0 8.7 0.016 14.7 0.1 5.9 5 1 1 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 CEP12785.1 - 6.7e-05 23.0 26.1 0.17 11.9 0.1 8.0 5 4 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CEP12785.1 - 0.00015 21.1 13.2 0.019 14.2 0.4 5.6 5 2 1 6 6 6 2 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 CEP12785.1 - 0.00029 21.0 9.4 0.66 10.1 1.3 6.1 5 1 0 6 6 6 1 V-ATPase subunit H DUF3361 PF11841.8 CEP12785.1 - 0.00076 19.4 4.2 3.8 7.4 0.0 5.5 4 1 1 5 5 5 1 Domain of unknown function (DUF3361) TAF6_C PF07571.13 CEP12785.1 - 0.0072 16.6 3.0 2.2 8.6 0.0 5.0 5 1 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain PUL PF08324.11 CEP12785.1 - 0.0096 15.2 1.0 0.75 9.0 0.0 3.6 3 0 0 3 3 3 1 PUL domain Telomere_reg-2 PF10193.9 CEP12785.1 - 0.01 16.3 5.9 7 7.2 0.0 5.6 5 1 0 5 5 5 0 Telomere length regulation protein Sec7_N PF12783.7 CEP12785.1 - 0.026 14.4 17.6 0.25 11.2 0.1 5.6 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Vel1p PF10339.9 CEP12785.1 - 0.1 12.0 0.1 0.62 9.4 0.0 2.3 2 1 1 3 3 3 0 Yeast-specific zinc responsive Imm5 PF14423.6 CEP12785.1 - 0.2 11.9 3.6 1 9.6 1.4 2.9 3 0 0 3 3 3 0 Immunity protein Imm5 NopRA1 PF16201.5 CEP12785.1 - 0.28 10.7 7.8 2.5 7.7 0.1 5.2 6 0 0 6 6 6 0 Nucleolar pre-ribosomal-associated protein 1 IFRD PF05004.13 CEP12785.1 - 2.4 7.2 18.3 5.3 6.1 0.2 6.8 5 3 1 6 6 6 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 CEP12785.1 - 2.6 8.2 9.9 42 4.4 0.0 6.6 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat DNA_pol_phi PF04931.13 CEP12785.1 - 8.8 4.3 21.4 1.4 7.0 6.8 3.4 3 0 0 3 3 3 0 DNA polymerase phi FCH PF00611.23 CEP12786.1 - 6.8e-06 26.3 0.4 2.4e-05 24.5 0.4 2.1 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain FAM184 PF15665.5 CEP12786.1 - 0.038 13.8 3.5 0.079 12.7 3.5 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B MRP-S31 PF15433.6 CEP12786.1 - 0.1 12.2 2.4 0.17 11.5 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 KxDL PF10241.9 CEP12786.1 - 0.65 10.3 6.8 1.2 9.5 0.2 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein Muted PF14942.6 CEP12786.1 - 0.67 10.3 9.0 7.1 7.0 0.4 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Sulfotransfer_4 PF17784.1 CEP12787.1 - 5.1e-59 199.7 0.0 5.8e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEP12787.1 - 0.043 14.2 0.1 0.34 11.3 0.1 2.3 1 1 0 1 1 1 0 Sulfotransferase family Aminotran_4 PF01063.19 CEP12788.1 - 1.6e-25 90.3 0.0 1.9e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DnaJ-X PF14308.6 CEP12789.1 - 3e-52 177.1 2.4 4.5e-52 176.6 0.2 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CEP12789.1 - 2.2e-25 88.5 0.4 5.9e-25 87.2 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Nucleos_tra2_C PF07662.13 CEP12790.1 - 3e-71 239.5 3.4 3e-71 239.5 3.4 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CEP12790.1 - 2.6e-20 72.8 6.0 2.6e-20 72.8 6.0 3.7 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus TssO PF17561.2 CEP12790.1 - 2.4 8.3 4.2 34 4.5 0.0 3.1 3 0 0 3 3 3 0 Type VI secretion system, TssO Sec2p PF06428.11 CEP12791.1 - 2.1e-18 66.1 11.6 2.1e-18 66.1 11.6 2.7 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p Laminin_I PF06008.14 CEP12791.1 - 0.019 14.7 13.6 0.034 13.9 13.6 1.4 1 0 0 1 1 1 0 Laminin Domain I DNA_alkylation PF08713.11 CEP12791.1 - 0.022 14.5 0.9 0.036 13.8 0.0 1.7 2 0 0 2 2 2 0 DNA alkylation repair enzyme LptF_LptG PF03739.14 CEP12791.1 - 0.093 11.6 0.9 0.099 11.5 0.1 1.4 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF5082 PF16888.5 CEP12791.1 - 0.15 12.3 18.7 0.6 10.4 15.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CEP12791.1 - 0.2 12.2 14.0 1.3 9.6 0.7 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 CEP12791.1 - 0.25 11.6 25.1 0.06 13.6 16.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APC_N_CC PF16689.5 CEP12791.1 - 1.3 9.1 11.0 6.1 7.0 0.1 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain DUF745 PF05335.13 CEP12791.1 - 2.1 8.0 13.4 9.8 5.8 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc7 PF08317.11 CEP12791.1 - 3.8 6.3 23.8 4.2 6.1 18.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2120 PF09893.9 CEP12791.1 - 4.2 7.5 8.6 2.9 8.0 5.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DASH_Hsk3 PF08227.11 CEP12791.1 - 5 7.6 6.3 3.6 8.0 0.4 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like GAS PF13851.6 CEP12791.1 - 6 6.2 25.3 14 4.9 25.2 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_tranf_2_3 PF13641.6 CEP12792.1 - 6.5e-26 91.6 0.0 1e-25 91.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NIF PF03031.18 CEP12792.1 - 1.2e-24 86.9 0.2 2.4e-24 85.9 0.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glycos_transf_2 PF00535.26 CEP12792.1 - 5.1e-09 36.2 0.0 9.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP12792.1 - 2.6e-06 27.0 0.3 4.9e-05 22.9 0.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 21 SLIDE PF09111.10 CEP12792.1 - 0.09 12.8 0.1 0.42 10.7 0.1 2.2 1 0 0 1 1 1 0 SLIDE RT_RNaseH PF17917.1 CEP12794.1 - 1.3e-35 121.9 0.0 3.6e-35 120.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP12794.1 - 1.6e-33 114.7 0.0 3.8e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP12794.1 - 1.4e-27 96.7 0.1 3.5e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP12794.1 - 3.7e-20 71.8 0.8 1.8e-19 69.6 0.2 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CEP12794.1 - 2.1e-14 53.7 0.0 1.3e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 CEP12794.1 - 8.1e-14 51.3 1.8 1.8e-13 50.1 1.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP12794.1 - 3.2e-05 24.0 0.1 6.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger OCIA PF07051.11 CEP12794.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) RVP_2 PF08284.11 CEP12795.1 - 1e-05 25.3 0.1 1.8e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CEP12795.1 - 0.0021 18.6 0.0 0.0042 17.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP12795.1 - 0.0024 18.5 0.0 0.0058 17.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 CEP12795.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.17 CEP12796.1 - 8.5e-06 26.0 2.0 2.4e-05 24.5 0.0 2.7 4 0 0 4 4 4 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP12796.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.6 CEP12796.1 - 0.037 13.8 0.2 0.037 13.8 0.2 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RP-C_C PF11800.8 CEP12796.1 - 0.43 10.6 8.5 1.1 9.4 2.7 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region rve PF00665.26 CEP12797.1 - 3.8e-15 56.1 0.0 1.1e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CEP12797.1 - 2.5e-14 53.1 0.0 5.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP12797.1 - 2.7e-07 30.6 0.1 5.8e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CEP12797.1 - 4.7e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEP12797.1 - 0.00022 21.4 0.1 0.00062 19.9 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger AAA_29 PF13555.6 CEP12797.1 - 0.14 11.9 0.1 29 4.5 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4514 PF14986.6 CEP12801.1 - 0.16 12.0 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) SPATA24 PF15175.6 CEP12803.1 - 0.0021 18.0 1.2 0.0021 18.0 1.2 2.4 3 0 0 3 3 3 1 Spermatogenesis-associated protein 24 Retrotrans_gag PF03732.17 CEP12803.1 - 0.005 17.1 0.2 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Ribosomal_L1 PF00687.21 CEP12806.1 - 2.2e-45 154.9 0.7 2.7e-45 154.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 CEP12806.1 - 0.25 11.4 3.2 0.41 10.7 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF4939 PF16297.5 CEP12807.1 - 0.0042 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) gag-asp_proteas PF13975.6 CEP12808.1 - 0.00074 20.0 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP12808.1 - 0.0029 18.2 0.0 0.0059 17.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotran_gag_2 PF14223.6 CEP12809.1 - 0.009 15.7 0.8 0.009 15.7 0.8 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Chromo PF00385.24 CEP12810.1 - 1e-07 31.7 1.0 1.7e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NPV_P10 PF05531.12 CEP12810.1 - 0.1 13.1 0.4 0.36 11.3 0.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein eIF3m_C_helix PF18005.1 CEP12811.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix RT_RNaseH_2 PF17919.1 CEP12812.1 - 1.5e-22 79.5 0.0 3.5e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP12812.1 - 4.1e-16 59.2 0.0 9.4e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP12812.1 - 1e-07 31.7 1.1 6.4e-06 25.8 0.4 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pepsin-I3 PF06394.13 CEP12812.1 - 0.029 14.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain rve PF00665.26 CEP12813.1 - 7.9e-14 51.9 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP12813.1 - 1.7e-09 37.4 0.2 3.8e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PBP_dimer PF03717.15 CEP12813.1 - 0.041 14.2 1.4 0.054 13.8 0.0 1.9 2 1 0 2 2 2 0 Penicillin-binding Protein dimerisation domain SR-25 PF10500.9 CEP12814.1 - 0.00077 19.1 10.2 0.00094 18.9 10.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Mito_fiss_reg PF05308.11 CEP12814.1 - 0.008 16.3 18.3 0.0095 16.0 18.3 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF2681 PF10883.8 CEP12814.1 - 0.017 15.5 27.4 0.038 14.4 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DDHD PF02862.17 CEP12814.1 - 0.058 13.5 9.6 0.069 13.3 9.6 1.2 1 0 0 1 1 1 0 DDHD domain BNIP3 PF06553.12 CEP12814.1 - 0.074 12.7 9.6 0.1 12.3 9.6 1.2 1 0 0 1 1 1 0 BNIP3 GCD14 PF08704.10 CEP12814.1 - 0.2 11.3 7.5 0.32 10.6 7.5 1.4 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Neur_chan_memb PF02932.16 CEP12814.1 - 0.21 11.6 9.3 0.27 11.3 9.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.8 CEP12814.1 - 0.22 11.4 11.8 0.25 11.2 11.8 1.1 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CEP12814.1 - 0.25 11.3 24.5 0.29 11.1 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 CEP12814.1 - 0.27 10.8 15.9 0.31 10.6 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 CEP12814.1 - 0.61 9.9 12.8 0.75 9.6 12.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CEP12814.1 - 0.79 10.0 13.7 0.94 9.7 13.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hydin_ADK PF17213.3 CEP12814.1 - 1.1 9.5 12.5 1.5 9.0 12.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Menin PF05053.13 CEP12814.1 - 1.3 7.3 9.8 1.6 7.0 9.8 1.0 1 0 0 1 1 1 0 Menin Folate_carrier PF01770.18 CEP12814.1 - 1.4 7.6 5.1 1.7 7.3 5.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier LMBR1 PF04791.16 CEP12814.1 - 1.5 7.6 12.4 1.8 7.4 12.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.13 CEP12814.1 - 2.3 7.9 10.6 2.9 7.6 10.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Zip PF02535.22 CEP12814.1 - 2.9 7.0 6.2 3.2 6.9 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MRP-S25 PF13741.6 CEP12814.1 - 3.4 7.2 18.3 1.2 8.7 14.6 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S25 Ndc1_Nup PF09531.10 CEP12814.1 - 3.7 6.1 14.7 4.1 6.0 14.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CEP12814.1 - 3.7 6.2 15.5 4.8 5.9 15.5 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CEP12814.1 - 4.5 4.3 16.2 4.9 4.1 16.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CEP12814.1 - 7.4 4.6 18.1 8.5 4.4 18.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.14 CEP12814.1 - 8.3 6.3 17.8 10 6.0 17.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RVT_1 PF00078.27 CEP12815.1 - 1.2e-15 57.6 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Baculo_PEP_C PF04513.12 CEP12816.1 - 0.0004 20.4 0.9 0.0009 19.3 0.9 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 CEP12816.1 - 0.0012 18.9 2.6 0.0012 18.9 2.6 1.5 2 0 0 2 2 1 1 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 CEP12816.1 - 0.0032 17.9 1.8 0.0079 16.6 1.0 2.1 2 1 0 2 2 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 CEP12816.1 - 0.0086 16.1 1.8 0.29 11.1 1.0 2.4 2 0 0 2 2 2 1 Laminin Domain II Apolipoprotein PF01442.18 CEP12816.1 - 0.014 15.3 0.1 0.031 14.2 0.1 1.6 2 0 0 2 2 1 0 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 CEP12816.1 - 0.014 15.6 1.2 0.029 14.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Prominin PF05478.11 CEP12816.1 - 0.014 13.4 1.1 0.024 12.6 1.1 1.3 1 0 0 1 1 1 0 Prominin LcrV PF04792.12 CEP12816.1 - 0.036 13.4 0.4 0.056 12.7 0.4 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein DUF16 PF01519.16 CEP12816.1 - 0.041 14.4 1.2 0.24 11.9 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF677 PF05055.12 CEP12816.1 - 0.049 12.5 0.5 0.074 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) FlaC_arch PF05377.11 CEP12816.1 - 0.054 13.9 5.9 2.2 8.7 3.4 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tweety PF04906.13 CEP12816.1 - 0.077 11.6 0.2 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 Tweety Syntaxin_2 PF14523.6 CEP12816.1 - 0.084 13.2 2.6 2.7 8.4 0.4 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Katanin_con80 PF13925.6 CEP12816.1 - 0.1 12.6 0.7 8.2 6.4 0.1 2.6 2 1 1 3 3 3 0 con80 domain of Katanin DUF2203 PF09969.9 CEP12816.1 - 0.1 13.3 0.2 5.3 7.8 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) BORCS7 PF16088.5 CEP12816.1 - 0.12 12.7 7.8 1.7 9.0 2.1 2.8 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 7 Prefoldin_2 PF01920.20 CEP12816.1 - 0.15 12.1 0.1 0.56 10.2 0.1 2.0 1 0 0 1 1 1 0 Prefoldin subunit HsbA PF12296.8 CEP12816.1 - 0.15 12.5 2.6 1 9.8 2.6 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Syntaxin-6_N PF09177.11 CEP12816.1 - 0.19 12.3 1.2 4.4 7.9 0.2 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 CEP12816.1 - 0.2 11.7 3.4 0.32 11.0 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CEP12816.1 - 0.21 11.9 2.5 0.79 10.0 2.3 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 CEP12816.1 - 0.28 10.4 0.6 0.8 8.9 0.3 1.7 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 CEP12816.1 - 0.35 11.1 1.9 0.45 10.7 0.7 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BORCS6 PF10157.9 CEP12816.1 - 0.35 11.1 4.8 0.29 11.4 2.9 1.8 2 1 0 2 2 1 0 BLOC-1-related complex sub-unit 6 LPP PF04728.13 CEP12816.1 - 0.47 10.9 7.4 0.73 10.3 0.8 3.1 2 1 1 3 3 2 0 Lipoprotein leucine-zipper Mononeg_RNA_pol PF00946.19 CEP12818.1 - 4.4e-85 286.2 6.9 2.1e-66 224.4 1.1 2.0 2 0 0 2 2 2 2 Mononegavirales RNA dependent RNA polymerase rve PF00665.26 CEP12819.1 - 6.7e-19 68.2 0.0 1.5e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP12819.1 - 1.1e-14 54.3 4.2 1.5e-14 53.8 2.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP12819.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CEP12819.1 - 0.0025 17.6 0.0 0.0078 16.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Collectrin PF16959.5 CEP12819.1 - 0.85 9.4 3.5 19 5.0 0.3 2.3 2 0 0 2 2 2 0 Renal amino acid transporter FAM76 PF16046.5 CEP12821.1 - 1.1 8.6 10.2 0.13 11.6 1.0 2.8 3 0 0 3 3 3 0 FAM76 protein DUF5405 PF17399.2 CEP12822.1 - 0.019 15.2 0.6 0.06 13.6 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5405) VASt PF16016.5 CEP12823.1 - 5.7e-34 117.7 0.8 1.4e-33 116.5 0.8 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CEP12823.1 - 4.1e-27 95.4 3.5 7.7e-27 94.5 3.5 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CEP12823.1 - 3.4e-11 43.6 1.2 8.9e-10 39.0 0.1 3.0 2 0 0 2 2 2 1 PH domain BAR PF03114.18 CEP12823.1 - 4.2e-06 26.6 0.5 9.2e-06 25.5 0.5 1.5 1 0 0 1 1 1 1 BAR domain Ctr PF04145.15 CEP12823.1 - 0.088 13.4 2.2 1.8 9.2 0.0 3.4 3 0 0 3 3 3 0 Ctr copper transporter family Bet_v_1 PF00407.19 CEP12823.1 - 0.25 11.2 3.1 0.55 10.1 3.1 1.5 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family F-box-like PF12937.7 CEP12825.1 - 3.5e-08 33.2 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP12825.1 - 0.00042 20.1 0.1 0.00098 18.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain ABC_membrane_2 PF06472.15 CEP12827.1 - 1.3e-57 195.3 2.7 1.3e-57 195.3 2.7 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEP12827.1 - 5.7e-19 69.0 0.0 1.1e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CEP12827.1 - 1.1e-05 25.0 0.0 0.1 12.0 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEP12827.1 - 8.5e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEP12827.1 - 0.0046 17.5 0.2 0.011 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CEP12827.1 - 0.017 14.8 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEP12827.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP12827.1 - 0.033 14.6 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 CEP12827.1 - 0.034 13.9 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEP12827.1 - 0.051 13.5 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CEP12827.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP12827.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CEP12827.1 - 0.12 12.4 0.0 0.91 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DHDPS PF00701.22 CEP12828.1 - 5.5e-52 176.3 0.1 6.1e-52 176.1 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PucR PF07905.11 CEP12828.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family DUF4061 PF13270.6 CEP12829.1 - 0.0013 19.0 0.8 0.0027 18.0 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4061) XRCC4 PF06632.12 CEP12829.1 - 0.0088 14.9 0.8 0.01 14.7 0.8 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pheromone PF08015.11 CEP12829.1 - 1.3 10.1 5.0 3.7 8.7 5.0 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone WD40 PF00400.32 CEP12830.1 - 2e-40 136.0 19.2 5.3e-07 30.2 0.1 11.5 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.12 CEP12830.1 - 6.6e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CEP12830.1 - 8.9e-26 90.0 0.0 0.0065 16.8 0.0 9.9 3 2 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP12830.1 - 7.4e-09 35.0 4.5 0.02 13.9 0.0 6.8 4 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEP12830.1 - 1.2e-07 31.9 5.6 0.67 9.8 0.0 5.6 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEP12830.1 - 8.8e-05 22.0 0.0 0.44 9.8 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 CEP12830.1 - 0.00014 21.7 1.1 0.013 15.5 0.0 4.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CEP12830.1 - 0.00025 20.5 0.1 0.56 9.5 0.0 3.8 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 CEP12830.1 - 0.0022 17.1 0.3 3.2 6.7 0.0 3.6 5 0 0 5 5 5 2 Coatomer WD associated region RAB3GAP2_N PF14655.6 CEP12830.1 - 0.021 14.1 0.2 0.5 9.6 0.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_3 PF15911.5 CEP12830.1 - 0.1 12.7 0.0 0.44 10.6 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat FmiP_Thoc5 PF09766.9 CEP12831.1 - 1.6e-28 100.1 15.8 1.6e-28 100.1 15.8 1.5 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 FAM194 PF14977.6 CEP12831.1 - 0.092 12.1 3.9 0.16 11.2 0.3 2.1 2 0 0 2 2 2 0 FAM194 protein RNA_pol_Rpb2_45 PF10385.9 CEP12831.1 - 0.13 12.5 0.9 0.36 11.1 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Spc7 PF08317.11 CEP12832.1 - 6.8e-45 153.3 13.4 1.3e-44 152.3 13.4 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 CEP12832.1 - 1.1e-05 24.0 0.1 1.1e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 DUF5082 PF16888.5 CEP12832.1 - 0.036 14.4 11.2 3 8.2 0.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Sulfate_transp PF00916.20 CEP12834.1 - 1.4e-84 284.1 20.9 7.8e-66 222.4 9.1 2.5 3 0 0 3 3 3 2 Sulfate permease family G-patch_2 PF12656.7 CEP12834.1 - 1.5e-21 76.3 0.5 3.8e-21 74.9 0.5 1.8 1 0 0 1 1 1 1 G-patch domain STAS PF01740.21 CEP12834.1 - 6.8e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CEP12834.1 - 0.0011 19.3 0.1 0.0026 18.1 0.1 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP12834.1 - 0.0015 18.9 2.2 0.0058 17.0 2.2 2.1 1 0 0 1 1 1 1 Molybdate transporter of MFS superfamily G-patch PF01585.23 CEP12834.1 - 0.007 16.2 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 G-patch domain RIFIN PF02009.16 CEP12834.1 - 0.32 10.8 8.9 0.023 14.6 3.7 1.7 2 0 0 2 2 2 0 Rifin HlyD_D4 PF16572.5 CEP12837.1 - 0.024 14.5 0.0 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB Ndc1_Nup PF09531.10 CEP12837.1 - 0.027 13.2 15.0 0.043 12.5 15.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CEP12837.1 - 0.4 8.9 20.5 0.48 8.6 20.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF2_N PF00176.23 CEP12838.1 - 1.7e-63 214.5 1.3 3.8e-63 213.3 1.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP12838.1 - 7e-20 71.4 0.5 3.6e-19 69.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP12838.1 - 3.6e-11 43.4 0.0 3.6e-11 43.4 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 CEP12838.1 - 5.5e-09 36.2 6.0 5.5e-09 36.2 6.0 4.6 3 1 1 4 4 4 1 HSA DEAD PF00270.29 CEP12838.1 - 0.00012 21.9 0.0 0.0007 19.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 CEP12838.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain HLH PF00010.26 CEP12839.1 - 1.3e-11 44.2 0.3 2.6e-11 43.3 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dicty_REP PF05086.12 CEP12839.1 - 1.2 7.0 7.8 2.1 6.2 7.8 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YabA PF06156.13 CEP12839.1 - 1.7 9.3 5.2 3.9 8.2 4.4 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Ribosomal_L44 PF00935.19 CEP12841.1 - 4.5e-38 129.6 10.1 6.6e-38 129.1 10.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 PseudoU_synth_2 PF00849.22 CEP12842.1 - 2e-26 93.0 0.0 3.7e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase RRM_1 PF00076.22 CEP12843.1 - 6.4e-27 93.2 0.0 7.5e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP12843.1 - 0.017 15.2 0.0 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif CNOT1_TTP_bind PF16417.5 CEP12843.1 - 0.27 10.4 11.9 2.8 7.1 9.0 2.6 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Carboxyl_trans PF01039.22 CEP12844.1 - 1.5e-77 261.3 0.0 1.9e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Ku PF02735.16 CEP12846.1 - 5.9e-30 104.5 0.2 1e-29 103.7 0.2 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CEP12846.1 - 2e-26 92.5 0.1 4.8e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 CEP12846.1 - 4e-16 59.4 0.2 7e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CEP12846.1 - 0.016 15.9 0.0 0.051 14.3 0.0 1.9 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm A_deaminase PF00962.22 CEP12847.1 - 1.1e-124 416.0 0.0 1.5e-124 415.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-RVT PF13966.6 CEP12848.1 - 1.7e-05 25.4 0.6 4.2e-05 24.2 0.6 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP12849.1 - 6.5e-15 55.3 0.4 1.1e-14 54.5 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP12849.1 - 1.8e-06 27.9 0.2 5.8e-06 26.3 0.2 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotran_gag_2 PF14223.6 CEP12851.1 - 0.011 15.4 0.8 0.011 15.4 0.8 1.7 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type NTP_transf_4 PF13562.6 CEP12852.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase RRM_1 PF00076.22 CEP12854.1 - 3.4e-24 84.4 2.1 1e-07 31.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP12854.1 - 4.4e-10 39.3 0.0 0.1 12.5 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_3 PF08777.11 CEP12854.1 - 5.3e-05 23.2 0.4 0.034 14.2 0.1 3.4 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 CEP12854.1 - 0.0015 18.5 0.0 6.4 6.9 0.1 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CEP12854.1 - 0.0026 17.6 0.5 0.37 10.6 0.0 2.9 2 2 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_Rrp7 PF17799.1 CEP12854.1 - 0.011 15.6 0.1 0.32 10.8 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain DUF1866 PF08952.11 CEP12854.1 - 0.016 15.1 0.0 5.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) DUF3808 PF10300.9 CEP12855.1 - 2.6e-63 214.4 3.0 1.5e-62 211.9 1.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) Sugar_tr PF00083.24 CEP12856.1 - 4.8e-72 243.3 15.9 5.3e-72 243.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP12856.1 - 5.3e-16 58.5 33.9 4.9e-08 32.3 1.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1390 PF07150.11 CEP12857.1 - 0.069 12.8 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DDE_Tnp_1_7 PF13843.6 CEP12858.1 - 3.5e-08 33.1 0.0 2.2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Transposase IS4 Prp18 PF02840.15 CEP12859.1 - 0.26 11.3 1.4 20 5.2 0.6 2.2 1 1 1 2 2 2 0 Prp18 domain DUF4509 PF14970.6 CEP12860.1 - 0.012 15.5 0.7 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) Yos1 PF08571.10 CEP12860.1 - 0.13 12.6 0.6 13 6.1 0.0 3.0 3 0 0 3 3 3 0 Yos1-like DUF1178 PF06676.11 CEP12860.1 - 0.22 11.9 4.5 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) BPL_N PF09825.9 CEP12860.1 - 0.29 10.2 6.2 0.73 8.8 6.2 1.9 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal TSC22 PF01166.18 CEP12861.1 - 2.2e-05 24.7 0.2 4.7e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 CEP12861.1 - 0.0021 18.6 1.5 0.0041 17.7 1.5 1.6 1 0 0 1 1 1 1 Initiation control protein YabA CCDC106 PF15794.5 CEP12861.1 - 0.026 14.2 1.4 0.048 13.4 1.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DivIC PF04977.15 CEP12861.1 - 0.057 13.2 0.5 0.057 13.2 0.5 2.1 2 0 0 2 2 2 0 Septum formation initiator HALZ PF02183.18 CEP12861.1 - 0.068 13.4 0.6 0.14 12.4 0.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 CEP12861.1 - 0.07 13.6 4.3 0.16 12.4 4.4 1.7 1 1 0 1 1 1 0 Cell division protein ZapB RasGAP_C PF03836.15 CEP12861.1 - 0.091 12.9 3.2 0.16 12.1 3.2 1.4 1 0 0 1 1 1 0 RasGAP C-terminus bZIP_2 PF07716.15 CEP12861.1 - 0.094 12.8 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Basic region leucine zipper ADIP PF11559.8 CEP12861.1 - 0.25 11.4 8.6 0.5 10.4 8.6 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 CEP12861.1 - 0.27 11.7 6.9 0.79 10.2 6.9 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Integrase_H2C2 PF17921.1 CEP12862.1 - 3.2e-21 75.2 0.0 5.1e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain PIF1 PF05970.14 CEP12863.1 - 9.9e-14 51.3 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 CEP12863.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CEP12863.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEP12863.1 - 0.057 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 CEP12863.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.16 CEP12864.1 - 1.7e-38 132.5 24.4 2e-38 132.2 24.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily eRF1_2 PF03464.15 CEP12865.1 - 7.7e-43 146.0 0.0 1.4e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEP12865.1 - 1.6e-36 125.2 0.0 3.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CEP12865.1 - 2.3e-17 63.2 0.0 3.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CEP12865.1 - 3.9e-08 33.7 0.0 7.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CEP12865.1 - 4.4e-07 30.2 0.0 6.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribosomal_L7Ae PF01248.26 CEP12865.1 - 0.097 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Lactamase_B PF00753.27 CEP12866.1 - 3.7e-09 36.9 1.5 5e-08 33.2 1.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TPR_1 PF00515.28 CEP12866.1 - 9.3e-08 31.6 4.7 0.014 15.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP12866.1 - 4.4e-07 29.5 6.2 0.032 14.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP12866.1 - 6e-07 29.7 4.0 4.3e-05 23.7 1.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.7 CEP12866.1 - 0.00021 21.4 1.8 0.0058 16.7 1.8 2.2 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 CEP12866.1 - 0.0006 19.8 3.3 0.47 10.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP12866.1 - 0.0026 17.7 0.3 0.42 10.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP12866.1 - 0.0054 17.4 2.0 0.3 11.8 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 CEP12866.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TPR_19 PF14559.6 CEP12866.1 - 0.019 15.4 2.2 1.3 9.6 0.1 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEP12866.1 - 0.042 13.5 0.7 0.49 10.1 0.0 2.8 2 1 1 3 3 3 0 TPR repeat DUF4899 PF16240.5 CEP12866.1 - 0.093 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) COR PF16095.5 CEP12866.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain ANAPC3 PF12895.7 CEP12866.1 - 0.14 12.4 1.5 0.36 11.1 1.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CEP12866.1 - 0.17 12.8 0.2 1.4 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RestrictionSfiI PF11487.8 CEP12867.1 - 0.00081 19.3 0.3 0.0012 18.8 0.3 1.4 1 0 0 1 1 1 1 Type II restriction enzyme SfiI IpaB_EvcA PF03278.13 CEP12867.1 - 0.14 11.9 5.3 3.7 7.3 0.6 3.0 2 1 0 2 2 2 0 IpaB/EvcA family DUF4168 PF13767.6 CEP12867.1 - 4.5 8.5 6.5 10 7.4 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) HEAT PF02985.22 CEP12868.1 - 6.2e-28 94.5 11.1 3.2e-05 23.8 0.3 10.8 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 CEP12868.1 - 2.7e-24 85.4 0.1 4e-07 30.3 0.0 7.4 5 2 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 CEP12868.1 - 9e-20 70.8 5.8 2.7e-06 27.8 0.1 9.0 7 2 3 10 10 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEP12868.1 - 8.7e-15 55.1 0.3 0.001 19.6 0.0 6.6 6 1 1 7 7 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CEP12868.1 - 9.8e-13 48.5 8.8 1.5e-06 28.3 0.1 6.6 4 3 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CEP12868.1 - 2.7e-10 40.2 0.2 0.017 14.7 0.0 6.0 5 2 1 7 7 7 3 CLASP N terminal IBN_N PF03810.19 CEP12868.1 - 2.7e-09 36.8 0.9 1.1e-08 34.8 0.4 2.5 2 0 0 2 2 1 1 Importin-beta N-terminal domain IFRD PF05004.13 CEP12868.1 - 9.1e-08 31.5 0.4 0.047 12.8 0.0 5.3 3 1 2 5 5 5 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 CEP12868.1 - 9.2e-07 28.7 2.6 0.15 12.2 0.0 5.7 6 1 1 7 7 5 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CEP12868.1 - 4.6e-06 25.5 3.6 9.4e-05 21.1 0.1 4.1 3 3 1 4 4 4 1 Adaptin N terminal region MMS19_C PF12460.8 CEP12868.1 - 6.4e-06 25.5 3.5 0.00073 18.8 0.0 4.2 4 2 1 5 5 5 2 RNAPII transcription regulator C-terminal DRIM PF07539.12 CEP12868.1 - 9e-06 24.3 0.3 1.6 6.9 0.0 4.2 4 1 0 4 4 4 3 Down-regulated in metastasis RTP1_C1 PF10363.9 CEP12868.1 - 9.4e-06 25.8 0.1 0.67 10.2 0.0 4.9 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 CEP12868.1 - 0.00018 21.1 2.1 0.038 13.5 0.0 3.9 5 0 0 5 5 5 1 Tti2 family Importin_rep_6 PF18829.1 CEP12868.1 - 0.00024 21.2 1.2 0.011 15.9 0.3 3.7 3 0 0 3 3 3 1 Importin repeat 6 RIX1 PF08167.12 CEP12868.1 - 0.0091 15.8 0.1 8.7 6.0 0.0 3.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 CEP12868.1 - 0.059 11.8 3.3 0.099 11.1 0.3 2.9 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus MMS19_N PF14500.6 CEP12868.1 - 0.12 12.0 0.2 34 3.9 0.0 4.2 3 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II UNC45-central PF11701.8 CEP12868.1 - 0.42 10.6 3.2 30 4.6 0.0 4.8 5 1 1 6 6 5 0 Myosin-binding striated muscle assembly central Proteasome PF00227.26 CEP12869.1 - 2e-61 206.8 0.2 2.8e-61 206.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP12869.1 - 7.2e-11 41.6 0.1 2.7e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PH_14 PF17787.1 CEP12869.1 - 0.13 12.1 0.0 2 8.3 0.0 2.5 2 1 1 3 3 3 0 PH domain RasGEF PF00617.19 CEP12870.1 - 6e-52 176.4 2.0 1.1e-51 175.5 2.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP12870.1 - 6.7e-05 23.1 3.0 7.6e-05 22.9 0.1 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif MMR_HSR1 PF01926.23 CEP12870.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase VPS28 PF03997.12 CEP12871.1 - 0.039 13.6 0.1 0.055 13.1 0.1 1.2 1 0 0 1 1 1 0 VPS28 protein cNMP_binding PF00027.29 CEP12872.1 - 5.9e-39 132.0 0.0 3.5e-19 68.6 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain LRR_4 PF12799.7 CEP12872.1 - 8.3e-19 67.4 8.9 0.00034 20.9 0.3 7.2 6 1 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP12872.1 - 7.8e-18 63.0 12.5 0.082 13.0 0.0 9.5 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 CEP12872.1 - 1.2e-05 25.2 18.8 7.8 7.5 0.0 10.0 9 1 0 9 9 9 1 Leucine Rich Repeat F-box PF00646.33 CEP12872.1 - 8.7e-05 22.3 0.0 0.00047 19.9 0.0 2.3 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 CEP12872.1 - 0.00072 19.3 8.3 3.7 7.4 0.5 5.3 3 2 1 4 4 4 3 Leucine rich repeat Ribosomal_S10 PF00338.22 CEP12872.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e SAS4 PF15460.6 CEP12873.1 - 0.00017 21.6 9.4 0.00017 21.6 9.4 2.6 1 1 1 2 2 2 2 Something about silencing, SAS, complex subunit 4 Med19 PF10278.9 CEP12873.1 - 0.0092 15.9 3.6 0.0092 15.9 3.6 2.0 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 RRM_1 PF00076.22 CEP12874.1 - 2.7e-26 91.1 3.3 3.3e-12 46.0 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP12874.1 - 2e-08 34.1 1.2 0.001 19.0 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CEP12874.1 - 3.5e-05 23.4 0.0 0.023 14.3 0.0 2.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CEP12874.1 - 0.00044 20.1 0.0 0.019 14.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4523) RRM_7 PF16367.5 CEP12874.1 - 0.0033 17.5 0.1 0.026 14.7 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 CEP12874.1 - 0.061 13.4 0.1 12 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA binding domain DUF5314 PF17241.2 CEP12874.1 - 0.083 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5314) COQ9 PF08511.11 CEP12876.1 - 4.9e-14 51.9 0.3 3.1e-06 26.9 0.1 2.3 1 1 1 2 2 2 2 COQ9 RVT_1 PF00078.27 CEP12877.1 - 1e-30 107.0 0.0 2.5e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP12879.1 - 1.3e-05 25.7 0.0 1.8e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP12879.1 - 0.00013 22.5 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PolyA_pol PF01743.20 CEP12881.1 - 1.2e-29 103.3 0.0 2.4e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CEP12881.1 - 4.1e-07 29.7 0.0 9.3e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A CdhD PF03599.16 CEP12881.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Ribosomal_S13_N PF08069.12 CEP12882.1 - 6.4e-29 99.8 0.1 1.4e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CEP12882.1 - 5.6e-14 52.1 0.6 8.4e-14 51.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 TPT PF03151.16 CEP12883.1 - 9.6e-42 143.3 21.7 1.1e-41 143.1 21.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CEP12883.1 - 5.8e-13 48.7 22.2 6.9e-13 48.5 22.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CEP12883.1 - 7.3e-10 39.2 30.1 2.2e-05 24.6 13.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP12883.1 - 0.011 14.9 3.1 0.011 14.9 3.1 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter Phage_holin_3_2 PF04550.12 CEP12883.1 - 0.66 10.6 5.0 22 5.7 0.5 3.1 2 1 1 3 3 3 0 Phage holin family 2 N6_Mtase PF02384.16 CEP12884.1 - 6.8e-16 58.4 0.2 2.4e-13 50.0 0.0 3.2 2 1 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 CEP12884.1 - 5.9e-08 33.2 0.0 2.2e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 CEP12884.1 - 0.00037 20.6 0.0 0.0013 18.8 0.0 2.0 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain PAP_assoc PF03828.19 CEP12885.1 - 5e-17 61.8 0.1 1.3e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEP12885.1 - 4.2e-05 23.8 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain TMEM171 PF15471.6 CEP12885.1 - 0.058 12.4 0.8 0.098 11.6 0.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Polbeta PF18765.1 CEP12885.1 - 0.15 12.1 0.1 0.42 10.7 0.0 1.7 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase HA2 PF04408.23 CEP12886.1 - 1.9e-23 82.8 0.0 1.9e-23 82.8 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEP12886.1 - 1e-21 77.1 0.0 2.7e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEP12886.1 - 6e-12 45.9 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP12886.1 - 3.5e-08 33.4 0.1 6.8e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CEP12886.1 - 2.9e-06 27.6 0.0 8.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP12886.1 - 4.2e-05 23.9 0.1 8.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CEP12886.1 - 0.001 18.7 0.1 0.0023 17.6 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CEP12886.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CEP12886.1 - 0.0065 16.5 0.8 6.9 6.6 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CEP12886.1 - 0.0091 15.5 0.0 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 CEP12886.1 - 0.019 14.5 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEP12886.1 - 0.02 14.6 0.0 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 CEP12886.1 - 0.046 14.2 0.1 0.23 12.0 0.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CEP12886.1 - 0.055 14.0 0.1 0.19 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEP12886.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pribosyltran PF00156.27 CEP12887.1 - 2.1e-23 82.6 0.1 2.7e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEP12887.1 - 0.0083 15.6 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CEP12887.1 - 0.085 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase HTH_Tnp_Tc3_2 PF01498.18 CEP12888.1 - 1.4e-09 38.0 0.2 2.6e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP12888.1 - 0.00093 19.8 0.3 0.0018 18.8 0.1 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 CEP12888.1 - 0.094 12.8 0.8 44 4.3 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Ldh_1_C PF02866.18 CEP12891.1 - 1.9e-48 164.5 0.0 3.2e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CEP12891.1 - 1.5e-46 157.9 0.3 2.3e-46 157.4 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CEP12891.1 - 0.0062 16.1 1.2 2.1 7.9 0.0 2.6 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 CEP12891.1 - 0.011 15.1 1.1 0.11 11.8 0.1 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 CEP12891.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CEP12891.1 - 0.07 13.3 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CEP12891.1 - 0.074 13.5 0.2 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 CEP12893.1 - 1.5e-41 142.5 0.3 1.3e-21 77.1 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP12893.1 - 1.5e-10 40.8 0.3 6.3e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Dicty_REP PF05086.12 CEP12893.1 - 0.018 13.0 3.0 0.032 12.2 3.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kinase-like PF14531.6 CEP12893.1 - 0.085 12.2 0.1 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CEP12893.1 - 6.3 5.5 10.7 1.3 7.7 6.3 2.2 1 1 1 2 2 2 0 Fungal protein kinase Aa_trans PF01490.18 CEP12895.1 - 7.7e-54 183.0 33.9 8e-30 103.9 8.2 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF2839 PF10999.8 CEP12895.1 - 0.32 11.4 1.9 15 6.0 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) AA_permease_2 PF13520.6 CEP12895.1 - 2 7.2 44.2 25 3.5 44.2 2.4 1 1 0 1 1 1 0 Amino acid permease TPPK_C PF12555.8 CEP12895.1 - 3.6 7.7 7.7 1.7 8.7 1.9 3.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal F-box PF00646.33 CEP12896.1 - 2.6e-06 27.1 3.9 7.6e-06 25.7 0.6 3.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 CEP12896.1 - 2.8e-06 27.1 4.8 3e-06 27.0 3.2 2.0 2 0 0 2 2 2 1 F-box-like Nup35_RRM_2 PF14605.6 CEP12897.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CEP12898.1 - 0.0012 18.7 2.0 0.0019 18.0 0.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP12898.1 - 0.0013 19.0 2.5 0.0039 17.4 0.6 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEP12898.1 - 0.0023 18.2 0.7 0.0095 16.3 0.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP12898.1 - 0.039 14.0 1.0 0.095 12.7 0.1 2.2 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP12898.1 - 0.051 13.5 2.7 0.12 12.2 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP12898.1 - 0.48 10.4 5.1 0.12 12.4 0.8 2.2 2 0 0 2 2 2 0 zinc-RING finger domain COMM_domain PF07258.14 CEP12898.1 - 0.52 10.5 5.2 0.27 11.4 2.3 2.1 2 0 0 2 2 2 0 COMM domain SOGA PF11365.8 CEP12898.1 - 0.76 10.9 0.1 0.76 10.9 0.1 3.0 2 1 0 2 2 2 0 Protein SOGA Occludin_ELL PF07303.13 CEP12898.1 - 1.3 9.8 9.4 2.4 8.9 0.0 3.2 2 1 0 3 3 3 0 Occludin homology domain EcoEI_R_C PF08463.10 CEP12899.1 - 0.095 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal ATP-synt_C PF00137.21 CEP12901.1 - 8.9e-35 118.8 34.5 2.2e-23 82.4 14.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 CEP12901.1 - 1 9.1 5.5 2.9 7.6 1.2 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DS PF01916.17 CEP12902.1 - 3.7e-133 443.2 0.0 4.2e-133 443.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase HAD PF12710.7 CEP12902.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase IrmA PF18673.1 CEP12903.1 - 0.078 13.1 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 interleukin receptor mimic protein A PGBA_C PF15437.6 CEP12903.1 - 0.83 10.1 10.6 1.2 9.6 1.4 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DivIVA PF05103.13 CEP12903.1 - 1 9.5 7.9 0.87 9.7 6.0 1.7 1 1 1 2 2 2 0 DivIVA protein ubiquitin PF00240.23 CEP12904.1 - 1.2e-06 28.2 0.1 2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CEP12904.1 - 2.7e-05 24.7 0.2 0.00015 22.3 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP12904.1 - 0.00065 19.8 1.5 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UPF0047 PF01894.17 CEP12905.1 - 3.6e-32 110.9 0.0 4.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 HPP PF04982.13 CEP12906.1 - 4.4e-40 136.7 7.3 7e-40 136.0 7.3 1.3 1 0 0 1 1 1 1 HPP family DUF839 PF05787.13 CEP12906.1 - 0.088 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Phage_antitermQ PF06530.12 CEP12906.1 - 0.14 12.1 0.1 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Phage antitermination protein Q DUF1218 PF06749.12 CEP12906.1 - 0.68 10.5 4.4 4.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF3792 PF12670.7 CEP12906.1 - 0.87 9.8 9.0 0.26 11.4 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF4514 PF14986.6 CEP12906.1 - 7 6.7 5.9 2.5 8.1 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) BAG PF02179.16 CEP12907.1 - 9.6e-11 42.0 1.2 9.6e-11 42.0 1.2 3.6 4 1 0 4 4 4 1 BAG domain DUF2967 PF11179.8 CEP12907.1 - 0.028 12.6 11.7 0.042 12.0 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Dehydrin PF00257.19 CEP12907.1 - 0.044 14.4 7.5 0.074 13.6 6.2 2.0 1 1 0 1 1 1 0 Dehydrin rve PF00665.26 CEP12908.1 - 1.9e-08 34.5 0.0 3.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain FixQ PF05545.11 CEP12911.1 - 0.74 9.8 2.7 1.6 8.8 2.7 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CbiQ PF02361.16 CEP12911.1 - 2.5 7.7 5.0 3.9 7.0 5.0 1.2 1 0 0 1 1 1 0 Cobalt transport protein zf-CCHC PF00098.23 CEP12912.1 - 0.002 18.1 1.9 0.0031 17.5 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CEP12912.1 - 0.0058 16.9 0.1 0.0093 16.2 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Clathrin_H_link PF13838.6 CEP12912.1 - 0.027 14.4 0.1 0.074 13.0 0.1 1.7 1 0 0 1 1 1 0 Clathrin-H-link RVT_1 PF00078.27 CEP12913.1 - 0.0032 17.0 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL36 PF03586.13 CEP12913.1 - 0.11 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein RT_RNaseH_2 PF17919.1 CEP12914.1 - 3.2e-25 88.1 0.1 5.8e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP12914.1 - 1.7e-17 63.6 0.1 1.3e-16 60.8 0.1 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP12914.1 - 7.7e-06 25.9 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4477 PF14780.6 CEP12914.1 - 0.057 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) RT_RNaseH PF17917.1 CEP12915.1 - 6.8e-20 71.3 0.5 1.5e-19 70.2 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP12915.1 - 1.7e-15 56.8 0.2 3.3e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEP12915.1 - 3.8e-10 39.7 0.1 8.2e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP12915.1 - 9.4e-10 38.7 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CEP12916.1 - 6.5e-07 29.8 0.0 2.1e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 CEP12916.1 - 1.3e-06 28.6 0.0 0.0053 17.0 0.0 3.1 2 1 0 2 2 2 2 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP12916.1 - 6.1e-06 26.8 0.0 1.5e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP12916.1 - 1.5e-05 24.8 0.2 3.4e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP12916.1 - 0.00074 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CEP12916.1 - 0.0027 17.7 3.2 0.0065 16.5 3.2 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 CEP12916.1 - 0.13 12.2 0.1 24 4.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) DUF1758 PF05585.12 CEP12916.1 - 0.32 10.8 2.4 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF1758) HTH_psq PF05225.16 CEP12917.1 - 0.064 13.0 0.2 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain PIN_5 PF08745.11 CEP12917.1 - 0.071 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PINc domain ribonuclease FixQ PF05545.11 CEP12918.1 - 0.23 11.5 2.3 0.58 10.2 2.3 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Chitin_synth_2 PF03142.15 CEP12919.1 - 2.3e-226 752.5 1.7 3.5e-226 751.9 1.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP12919.1 - 7e-110 368.2 0.1 9.2e-110 367.9 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 CEP12919.1 - 1.7e-19 69.7 0.6 5.2e-14 52.1 0.1 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 CEP12919.1 - 3.7e-15 55.6 0.2 1e-14 54.2 0.2 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 CEP12919.1 - 3.2e-10 40.3 0.0 4e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP12919.1 - 1.8e-09 37.8 3.7 1.8e-09 37.8 3.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Pentapeptide_4 PF13599.6 CEP12921.1 - 0.017 15.3 0.4 0.25 11.6 0.0 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) F-box-like PF12937.7 CEP12923.1 - 4e-08 33.0 0.0 1.4e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like Pentapeptide_4 PF13599.6 CEP12923.1 - 0.0072 16.5 0.0 0.16 12.1 0.0 2.9 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) TFR_dimer PF04253.15 CEP12925.1 - 6.5e-21 74.7 0.1 1.2e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CEP12925.1 - 5.6e-20 71.9 0.7 2.3e-19 69.9 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M28 PA PF02225.22 CEP12925.1 - 4.3e-11 42.7 0.0 1.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 CEP12925.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 YchF-GTPase_C PF06071.13 CEP12926.1 - 2.9e-38 129.9 0.5 6e-38 128.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CEP12926.1 - 6.7e-22 77.7 0.0 1.6e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP12926.1 - 5.9e-08 32.4 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEP12926.1 - 0.0057 16.7 0.2 0.78 9.8 0.1 2.5 1 1 1 2 2 2 2 Dynamin family PCI PF01399.27 CEP12927.1 - 1.8e-15 57.4 3.0 2.3e-15 57.0 0.5 2.3 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 CEP12927.1 - 3.1e-05 24.0 0.2 8.1e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 CEP12927.1 - 0.0031 17.3 0.1 0.0069 16.1 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF5063 PF16702.5 CEP12927.1 - 0.42 11.0 4.8 0.31 11.4 1.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5063) DUF3384 PF11864.8 CEP12928.1 - 2.4e-62 211.4 4.6 2.4e-62 211.4 4.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 CEP12928.1 - 8.5e-50 168.9 0.1 2.4e-49 167.4 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 CEP12928.1 - 5.6e-41 140.8 16.9 3.2e-39 135.0 3.6 4.3 4 0 0 4 4 4 2 Tuberin MarC PF01914.17 CEP12928.1 - 0.038 13.4 0.1 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 MarC family integral membrane protein RAB3GAP2_N PF14655.6 CEP12928.1 - 0.15 11.2 10.5 0.012 15.0 1.8 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 CEP12928.1 - 0.43 9.5 26.1 0.024 13.6 4.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) DUF3439 PF11921.8 CEP12928.1 - 3.6 7.6 9.9 11 6.0 5.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) F-box-like PF12937.7 CEP12929.1 - 9.1e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like Dynactin_p22 PF07426.11 CEP12929.1 - 0.052 13.4 0.3 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 DUF3557 PF12078.8 CEP12929.1 - 0.13 12.2 1.0 2.1 8.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) FHA PF00498.26 CEP12931.1 - 1.5e-16 60.5 0.0 3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Macoilin PF09726.9 CEP12931.1 - 6.6e-06 25.0 14.2 9.4e-06 24.5 14.2 1.2 1 0 0 1 1 1 1 Macoilin family Yop-YscD_cpl PF16697.5 CEP12931.1 - 4.6e-05 23.7 0.0 0.00015 22.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DASH_Spc34 PF08657.10 CEP12931.1 - 0.0016 18.3 2.4 0.0022 17.8 2.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 Exonuc_VII_L PF02601.15 CEP12931.1 - 0.0089 15.6 11.0 0.014 14.9 11.0 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit HOOK PF05622.12 CEP12931.1 - 0.013 13.7 12.5 0.02 13.1 12.5 1.2 1 0 0 1 1 1 0 HOOK protein LMBR1 PF04791.16 CEP12931.1 - 0.025 13.5 3.3 0.033 13.1 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bcr-Abl_Oligo PF09036.10 CEP12931.1 - 0.035 14.1 6.9 1.3 9.1 1.7 2.5 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Lebercilin PF15619.6 CEP12931.1 - 0.063 12.9 22.1 0.25 11.0 19.7 2.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 CEP12931.1 - 0.071 13.1 19.0 0.26 11.3 15.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 CEP12931.1 - 0.087 10.7 8.3 0.13 10.2 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 CEP12931.1 - 0.14 12.6 14.6 1.6 9.1 11.7 2.3 1 1 1 2 2 2 0 Fez1 DUF3584 PF12128.8 CEP12931.1 - 0.3 8.6 15.5 0.43 8.0 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4763 PF15960.5 CEP12931.1 - 0.33 10.2 12.2 0.074 12.4 8.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) V-SNARE PF05008.15 CEP12931.1 - 0.43 11.0 10.9 1.7 9.1 0.5 2.7 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Sec62 PF03839.16 CEP12931.1 - 0.56 9.7 5.2 0.96 8.9 5.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 ABC_tran_CTD PF16326.5 CEP12931.1 - 1 9.6 17.1 0.36 11.1 4.0 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 CEP12931.1 - 1.1 9.2 5.6 0.74 9.8 1.7 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TMPIT PF07851.13 CEP12931.1 - 1.6 7.9 14.4 0.67 9.1 10.2 2.2 1 1 1 2 2 2 0 TMPIT-like protein FlaC_arch PF05377.11 CEP12931.1 - 2.1 8.8 9.8 12 6.3 0.9 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 CEP12931.1 - 3.2 8.5 11.8 35 5.2 7.9 2.7 1 1 1 2 2 2 0 Occludin homology domain Spc7 PF08317.11 CEP12931.1 - 3.3 6.5 21.1 0.34 9.8 12.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2802 PF10975.8 CEP12931.1 - 3.5 7.8 8.2 1.4 9.1 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2802) Prefoldin PF02996.17 CEP12931.1 - 7.8 6.4 12.1 27 4.7 0.5 3.4 2 1 1 3 3 3 0 Prefoldin subunit Methyltransf_11 PF08241.12 CEP12932.1 - 1.1e-15 58.0 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP12932.1 - 7.2e-13 49.1 0.0 2.2e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12932.1 - 2e-12 47.3 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12932.1 - 5.1e-06 27.1 0.0 9.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP12932.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CEP12932.1 - 0.00038 20.3 0.1 0.01 15.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 CEP12932.1 - 0.00085 18.0 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.12 CEP12932.1 - 0.001 18.6 0.0 0.0061 16.1 0.0 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 CEP12932.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.20 CEP12932.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 CEP12932.1 - 0.0066 16.0 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 CEP12932.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_16 PF10294.9 CEP12932.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CBFD_NFYB_HMF PF00808.23 CEP12933.1 - 9.1e-16 57.9 1.1 9.1e-16 57.9 1.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP12933.1 - 7.2e-05 23.2 0.7 0.0001 22.6 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ResIII PF04851.15 CEP12934.1 - 1.9e-19 70.3 0.0 2e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BAG PF02179.16 CEP12934.1 - 6.9e-14 52.0 1.4 2.2e-13 50.4 1.4 2.0 1 0 0 1 1 1 1 BAG domain Helicase_C PF00271.31 CEP12934.1 - 1.6e-12 47.8 0.0 8.2e-12 45.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP12934.1 - 7.4e-07 29.1 0.0 2.3e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEP12934.1 - 2.8e-06 27.2 0.1 9.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CEP12934.1 - 4.9e-05 22.7 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CEP12934.1 - 0.0099 16.2 0.4 1.3 9.3 0.0 4.2 3 1 1 4 4 4 1 AAA domain T2SSE PF00437.20 CEP12934.1 - 0.015 14.3 0.2 0.027 13.5 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Uso1_p115_C PF04871.13 CEP12934.1 - 0.23 11.9 6.4 0.064 13.6 2.5 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SelP_N PF04592.14 CEP12935.1 - 0.062 12.7 9.1 0.09 12.2 9.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Beta_elim_lyase PF01212.21 CEP12937.1 - 3.1e-68 230.2 0.0 4.2e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEP12937.1 - 2.4e-06 26.9 0.0 4.3e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CEP12937.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CEP12937.1 - 0.093 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PQ-loop PF04193.14 CEP12938.1 - 3.9e-37 125.8 13.0 9.3e-19 67.0 1.3 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CEP12938.1 - 0.32 11.1 6.6 0.44 10.6 0.1 3.2 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange PH_12 PF16457.5 CEP12941.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Rad51 PF08423.11 CEP12943.1 - 3e-104 347.8 0.1 1.1e-89 300.1 0.1 2.2 1 1 1 2 2 2 2 Rad51 RecA PF00154.21 CEP12943.1 - 3.5e-12 46.3 0.2 4.9e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CEP12943.1 - 1.3e-06 28.9 0.7 3e-06 27.7 0.7 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CEP12943.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEP12943.1 - 1.5e-06 27.7 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 CEP12943.1 - 0.00039 20.2 0.0 0.00091 19.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CEP12943.1 - 0.012 16.1 0.0 0.05 14.0 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_pol_A_CTD PF03118.15 CEP12943.1 - 0.026 14.3 0.2 0.07 12.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.6 CEP12943.1 - 0.03 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PTPLA PF04387.14 CEP12944.1 - 5.9e-54 182.2 15.2 7.8e-54 181.8 15.2 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2236 PF09995.9 CEP12946.1 - 0.0049 17.1 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) zf-CCCH PF00642.24 CEP12947.1 - 7.8e-19 67.1 20.1 8.2e-11 41.5 4.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CEP12947.1 - 1.2e-12 47.4 19.9 1.9e-06 27.7 6.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CEP12947.1 - 8.3e-09 35.0 16.9 0.00016 21.3 3.1 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CEP12947.1 - 0.0029 18.0 11.9 0.11 13.0 1.1 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Coatamer_beta_C PF07718.12 CEP12947.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.3 3 0 0 3 3 3 0 Coatomer beta C-terminal region oligo_HPY PF08352.12 CEP12947.1 - 9.4 6.8 10.6 8.6 7.0 2.1 2.9 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region NTP_transferase PF00483.23 CEP12948.1 - 3e-13 49.9 0.0 8.5e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CEP12948.1 - 1.9e-09 38.1 0.0 2.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CEP12948.1 - 1e-08 34.6 11.4 5.1e-05 22.8 6.9 3.6 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CEP12948.1 - 8.9e-05 20.8 4.3 8.9e-05 20.8 4.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CEP12948.1 - 0.01 14.8 6.7 0.063 12.2 6.7 1.9 1 1 0 1 1 1 0 L-fucokinase DUF4452 PF14618.6 CEP12949.1 - 0.00011 22.1 9.6 0.00011 22.1 9.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4452) SR-25 PF10500.9 CEP12949.1 - 5.4 6.6 17.2 4.4 6.9 5.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ciart PF15673.5 CEP12951.1 - 0.00066 19.1 1.1 0.00066 19.1 1.1 2.5 3 0 0 3 3 3 1 Circadian-associated transcriptional repressor KilA-N PF04383.13 CEP12951.1 - 0.0019 18.1 2.7 0.0019 18.0 0.0 2.4 2 1 0 2 2 2 1 KilA-N domain LupA PF18242.1 CEP12951.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain IL3 PF02059.15 CEP12951.1 - 0.37 10.9 3.5 0.68 10.0 0.0 2.7 3 0 0 3 3 3 0 Interleukin-3 pP_pnuc_1 PF18165.1 CEP12952.1 - 0.023 14.6 2.2 0.025 14.5 0.3 2.0 2 1 0 2 2 2 0 Predicted pPIWI-associating nuclease Cu_amine_oxid PF01179.20 CEP12953.1 - 5.8e-66 223.1 0.0 7.9e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CEP12953.1 - 1e-16 61.2 0.1 1.9e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CEP12953.1 - 1.9e-09 37.7 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Inhibitor_I78 PF11720.8 CEP12954.1 - 2.2e-07 30.9 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 CEP12954.1 - 0.0092 16.6 0.0 0.02 15.5 0.0 1.5 1 1 1 2 2 2 1 Potato inhibitor I family Ank_4 PF13637.6 CEP12955.1 - 3.3e-16 59.4 0.3 1.6e-10 41.3 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP12955.1 - 1.6e-15 57.4 6.1 5.2e-07 30.2 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CEP12955.1 - 2.2e-11 43.7 0.2 0.00017 21.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CEP12955.1 - 6.8e-10 38.3 0.1 5.3e-05 23.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP12955.1 - 2.6e-07 30.8 0.3 0.033 14.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 CEP12955.1 - 8e-05 22.5 0.1 0.00062 19.6 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Lipoprotein_6 PF01441.19 CEP12955.1 - 0.0096 15.9 0.3 0.0096 15.9 0.3 2.1 3 0 0 3 3 3 1 Lipoprotein MBOAT_2 PF13813.6 CEP12956.1 - 9.5e-11 41.8 1.2 4.2e-05 23.7 0.0 3.0 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family Med3 PF11593.8 CEP12956.1 - 0.21 10.7 8.9 0.28 10.3 8.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.19 CEP12956.1 - 0.22 12.1 7.3 0.37 11.4 7.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mucin PF01456.17 CEP12956.1 - 0.94 9.5 17.8 1.6 8.7 17.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CEP12956.1 - 6.1 4.7 6.3 8.2 4.3 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aldose_epim PF01263.20 CEP12957.1 - 1.5e-85 287.1 0.1 1.7e-85 286.9 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GPR_Gpa2_C PF11970.8 CEP12958.1 - 0.015 15.4 2.2 0.52 10.4 0.1 3.4 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2834 PF11196.8 CEP12958.1 - 0.019 15.3 2.0 0.019 15.3 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) PrgI PF12666.7 CEP12959.1 - 0.82 10.4 8.6 3.9 8.2 0.3 3.3 4 0 0 4 4 4 0 PrgI family protein DUF2207 PF09972.9 CEP12959.1 - 1.2 7.8 7.5 0.56 8.9 1.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UBX PF00789.20 CEP12960.1 - 5.4e-17 61.8 0.0 1.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain SH3BGR PF04908.15 CEP12960.1 - 0.39 10.9 0.1 0.39 10.9 0.1 3.3 2 1 1 3 3 3 0 SH3-binding, glutamic acid-rich protein DUF737 PF05300.11 CEP12960.1 - 0.63 10.4 25.3 1.6 9.1 25.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Asp-B-Hydro_N PF05279.11 CEP12960.1 - 4.5 7.3 22.5 8.7 6.3 22.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Creatinase_N_2 PF16189.5 CEP12962.1 - 1.8e-50 171.2 0.0 3.1e-49 167.2 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CEP12962.1 - 2.1e-42 145.2 0.0 5.1e-42 143.9 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CEP12962.1 - 9e-23 80.1 0.0 2.7e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CEP12962.1 - 1.8e-18 67.4 0.0 1.4e-16 61.3 0.0 2.6 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Sds3 PF08598.11 CEP12963.1 - 5e-11 43.0 7.2 5e-11 43.0 7.2 2.6 1 1 0 2 2 2 1 Sds3-like GrpE PF01025.19 CEP12963.1 - 0.15 11.7 5.1 0.23 11.1 4.7 1.6 1 1 0 1 1 1 0 GrpE Cofilin_ADF PF00241.20 CEP12964.1 - 1.3e-35 121.8 1.2 1.7e-35 121.4 1.2 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-CCHC_3 PF13917.6 CEP12965.1 - 8.9e-08 32.0 0.9 2.4e-07 30.6 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle SPX PF03105.19 CEP12965.1 - 0.77 9.6 39.8 0.89 9.4 39.8 1.0 1 0 0 1 1 1 0 SPX domain FSA_C PF10479.9 CEP12965.1 - 6.7 4.7 13.7 7.6 4.5 13.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Proteasome PF00227.26 CEP12966.1 - 5.6e-56 189.0 0.2 7.8e-56 188.6 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP12966.1 - 2.1e-15 56.1 0.1 3.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.22 CEP12968.1 - 3.1e-17 62.1 0.1 6.4e-08 32.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP12968.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF2367 PF10164.9 CEP12968.1 - 0.16 12.5 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) RBM39linker PF15519.6 CEP12968.1 - 0.21 12.7 0.9 0.91 10.7 0.1 2.2 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Nop16 PF09420.10 CEP12969.1 - 5.1e-60 203.1 12.4 6.2e-60 202.8 12.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Cation_efflux PF01545.21 CEP12970.1 - 8.1e-31 107.3 14.7 1.1e-30 106.9 14.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CEP12970.1 - 4.6e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GCR1_C PF12550.8 CEP12970.1 - 0.0001 22.5 0.0 0.00034 20.9 0.0 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sulfate_transp PF00916.20 CEP12971.1 - 8.9e-84 281.4 16.7 8.9e-84 281.4 16.7 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP12971.1 - 5.4e-24 84.1 0.0 9.4e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CEP12971.1 - 0.021 15.2 0.0 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 STAS domain Phage_holin_2_3 PF16080.5 CEP12971.1 - 0.47 10.2 2.5 1.6 8.6 2.5 1.9 1 0 0 1 1 1 0 Bacteriophage holin family HP1 WD40 PF00400.32 CEP12972.1 - 1.1e-41 140.0 17.4 1.1e-05 26.0 0.4 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP12972.1 - 1.6e-19 69.9 3.0 0.029 14.7 0.0 6.9 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP12972.1 - 9.5e-09 34.4 10.1 0.082 11.5 0.0 5.9 2 1 4 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP12972.1 - 2e-08 33.9 0.0 0.00063 19.2 0.0 2.6 1 1 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 CEP12972.1 - 3.6e-08 33.2 0.1 7e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 CEP12972.1 - 2e-07 31.0 0.2 0.15 12.1 0.0 5.1 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 CEP12972.1 - 0.00035 21.0 1.1 14 6.3 0.1 5.0 4 0 0 4 4 4 0 PQQ-like domain DUF5046 PF16465.5 CEP12972.1 - 0.00055 19.5 0.1 0.083 12.3 0.0 2.8 1 1 2 3 3 3 1 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 CEP12972.1 - 0.0015 17.5 0.8 1.3 7.9 0.0 3.8 1 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain F-box PF00646.33 CEP12972.1 - 0.0034 17.2 1.1 0.0095 15.8 0.1 2.2 2 0 0 2 2 2 1 F-box domain CNH PF00780.22 CEP12972.1 - 0.015 14.9 0.2 31 4.1 0.0 4.1 4 1 0 4 4 4 0 CNH domain CDC4_D PF16856.5 CEP12972.1 - 0.027 14.4 1.1 0.053 13.4 1.1 1.5 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Ge1_WD40 PF16529.5 CEP12972.1 - 0.042 12.8 0.2 0.46 9.4 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_ligase_A_N PF04675.14 CEP12972.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA ligase N terminus NUP214 PF16755.5 CEP12972.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PilO PF04350.13 CEP12972.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO Syntaxin PF00804.25 CEP12973.1 - 4.2e-36 124.5 18.1 4.2e-36 124.5 18.1 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CEP12973.1 - 3.3e-12 46.2 1.2 3.3e-12 46.2 1.2 2.8 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CEP12973.1 - 9.4e-06 25.9 13.3 9.4e-06 25.9 13.3 2.9 2 1 1 3 3 3 1 Syntaxin-like protein MCPsignal PF00015.21 CEP12973.1 - 0.012 15.5 5.3 0.012 15.5 5.3 3.4 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PDCD7 PF16021.5 CEP12973.1 - 0.14 11.2 18.9 0.42 9.7 15.2 2.6 2 1 0 2 2 2 0 Programmed cell death protein 7 Vac_Fusion PF02346.16 CEP12973.1 - 0.19 11.4 5.0 0.36 10.5 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Spectrin PF00435.21 CEP12973.1 - 0.2 12.2 10.4 1.9 9.0 0.4 2.9 2 2 0 2 2 2 0 Spectrin repeat DUF2203 PF09969.9 CEP12973.1 - 0.71 10.6 11.0 1.1 10.0 0.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Raf1_N PF18578.1 CEP12973.1 - 1.9 9.0 5.8 4.3 7.8 1.3 2.5 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain LMBR1 PF04791.16 CEP12973.1 - 5.3 5.8 22.0 65 2.2 22.0 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein CLZ PF16526.5 CEP12973.1 - 8.6 6.8 8.2 8.2 6.9 0.1 3.5 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CEP12973.1 - 9.6 6.4 28.2 2.3 8.4 4.9 3.3 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family F-box PF00646.33 CEP12974.1 - 0.27 11.2 4.7 0.085 12.8 1.0 2.2 2 0 0 2 2 2 0 F-box domain APG12 PF04110.13 CEP12975.1 - 2.5e-33 114.3 0.0 4e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CEP12975.1 - 0.00099 19.3 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.11 CEP12975.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain Retrotrans_gag PF03732.17 CEP12976.1 - 0.99 9.7 6.7 2.6 8.4 0.9 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein Chitin_synth_2 PF03142.15 CEP12977.1 - 5.4e-217 721.6 0.2 8.1e-217 721.0 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP12977.1 - 2e-13 50.8 0.0 2.7e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP12977.1 - 1.4e-09 38.2 5.5 1.4e-09 38.2 5.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CEP12977.1 - 4.3e-05 23.1 0.1 0.0012 18.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEP12977.1 - 0.034 14.0 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 CEP12977.1 - 0.18 12.0 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain PK PF00224.21 CEP12978.1 - 4.2e-167 555.4 2.6 5.2e-167 555.0 2.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CEP12978.1 - 6.8e-41 139.2 0.0 1.5e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CEP12978.1 - 0.00034 19.8 0.3 0.001 18.2 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DAHP_snth_FXD PF18152.1 CEP12978.1 - 0.0016 18.3 0.3 0.007 16.2 0.0 2.2 2 0 0 2 2 2 1 DAHP synthase ferredoxin-like domain IMPDH PF00478.25 CEP12978.1 - 0.059 12.4 0.1 0.51 9.3 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 CEP12978.1 - 0.083 12.3 0.1 0.23 10.9 0.1 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Mg_trans_NIPA PF05653.14 CEP12979.1 - 2.1e-60 204.3 14.5 2e-57 194.6 14.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CEP12979.1 - 0.00011 22.4 1.9 0.00011 22.4 1.9 4.0 3 1 0 3 3 3 1 EamA-like transporter family ATP19 PF11022.8 CEP12979.1 - 0.11 12.9 0.5 3.2 8.2 0.0 2.9 2 0 0 2 2 2 0 ATP synthase subunit K GPR_Gpa2_C PF11970.8 CEP12979.1 - 0.16 12.1 1.5 0.42 10.7 1.5 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term TssN PF17555.2 CEP12979.1 - 3.7 6.9 10.1 12 5.2 10.0 1.8 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF913 PF06025.12 CEP12980.1 - 0.049 12.6 4.5 0.037 13.0 2.7 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.8 CEP12980.1 - 0.078 13.2 8.3 0.1 12.9 8.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 CEP12980.1 - 0.11 12.1 10.4 0.12 11.9 10.4 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3134 PF11332.8 CEP12980.1 - 6.2 7.2 11.2 13 6.2 11.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) MT-A70 PF05063.14 CEP12982.1 - 3.9e-12 46.4 0.2 9.1e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 MT-A70 Methyltransf_21 PF05050.12 CEP12982.1 - 7e-06 26.2 0.0 3.9e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain COG2 PF06148.11 CEP12983.1 - 2.3e-23 82.8 4.1 3.9e-23 82.0 0.5 3.1 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CEP12983.1 - 1.2e-21 77.4 4.3 2.5e-21 76.3 0.4 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 CEP12983.1 - 1.5e-07 31.4 0.7 1.8e-06 27.9 0.1 3.1 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 CEP12983.1 - 0.006 15.5 2.0 0.006 15.5 2.0 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CEP12983.1 - 0.0067 16.5 22.1 0.024 14.7 1.2 4.9 6 0 0 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus KIP1 PF07765.12 CEP12983.1 - 0.014 15.5 2.0 0.058 13.5 0.4 2.9 2 0 0 2 2 2 0 KIP1-like protein GCN5L1 PF06320.13 CEP12983.1 - 0.014 15.5 0.2 0.014 15.5 0.2 2.8 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) FlaC_arch PF05377.11 CEP12983.1 - 0.025 14.9 0.5 0.025 14.9 0.5 3.6 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4349 PF14257.6 CEP12983.1 - 0.048 13.1 0.6 0.14 11.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3829 PF12889.7 CEP12983.1 - 0.06 12.8 11.2 0.17 11.4 1.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3829) Occludin_ELL PF07303.13 CEP12983.1 - 0.068 13.9 0.3 1.9 9.3 0.0 3.3 2 0 0 2 2 2 0 Occludin homology domain DUF2730 PF10805.8 CEP12983.1 - 0.27 11.3 4.3 0.34 11.0 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FadA PF09403.10 CEP12983.1 - 0.36 11.3 10.6 11 6.5 0.3 4.5 5 0 0 5 5 4 0 Adhesion protein FadA L31 PF09784.9 CEP12983.1 - 0.57 10.6 3.4 32 5.0 0.1 4.1 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L31 HIP1_clath_bdg PF16515.5 CEP12983.1 - 1.7 9.3 9.1 1.4 9.6 0.8 3.7 4 1 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5446 PF17522.2 CEP12983.1 - 5.4 7.3 10.9 0.46 10.7 0.4 4.4 4 2 2 6 6 5 0 Family of unknown function (DUF5446) Kelch_6 PF13964.6 CEP12984.1 - 1.4e-27 95.0 11.5 2.1e-08 34.2 0.1 5.9 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CEP12984.1 - 3e-26 91.2 15.9 3.3e-08 33.4 0.1 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP12984.1 - 1.2e-23 82.6 12.5 4.9e-08 32.8 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CEP12984.1 - 2.2e-22 78.4 8.2 6.8e-08 32.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CEP12984.1 - 1.8e-19 68.9 9.4 3.4e-06 26.8 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CEP12984.1 - 1.5e-15 57.0 10.5 0.00017 21.8 0.0 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain TA_inhibitor PF17574.2 CEP12984.1 - 0.47 10.5 3.2 0.56 10.3 0.1 2.7 3 1 0 3 3 3 0 Inhibitor of toxin/antitoxin system (Gp4.5) MSC PF09402.10 CEP12985.1 - 2.8e-50 171.7 0.0 6e-50 170.6 0.0 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain PBP1_TM PF14812.6 CEP12985.1 - 0.014 15.8 12.4 0.014 15.8 12.4 2.9 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HeH PF12949.7 CEP12985.1 - 0.024 14.4 0.2 0.13 12.0 0.2 2.4 1 1 0 1 1 1 0 HeH/LEM domain O-ag_pol_Wzy PF14296.6 CEP12985.1 - 0.098 11.3 0.2 0.19 10.4 0.0 1.5 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF4203 PF13886.6 CEP12986.1 - 2.4e-38 131.8 37.3 3.5e-38 131.3 37.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) COX14 PF14880.6 CEP12986.1 - 2.7 7.9 4.1 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DEAD PF00270.29 CEP12987.1 - 1.3e-48 165.1 0.7 3e-48 163.9 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP12987.1 - 3.6e-25 88.5 0.1 1.6e-24 86.4 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEP12987.1 - 1.8e-20 72.9 0.3 3.6e-20 71.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 CEP12987.1 - 2.3e-05 23.7 0.0 5.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CEP12987.1 - 2.4e-05 24.4 0.0 6.6e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEP12987.1 - 0.014 15.2 0.1 0.18 11.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain Hormone_3 PF00159.18 CEP12987.1 - 0.091 12.8 0.7 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Pancreatic hormone peptide DUF3368 PF11848.8 CEP12987.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) DDE_Tnp_4 PF13359.6 CEP12988.1 - 1.5e-11 44.2 0.0 1.7e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 CEP12988.1 - 0.049 13.4 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Peptidase_M16 PF00675.20 CEP12989.1 - 5.5e-56 188.7 0.9 7.7e-55 185.0 0.3 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEP12989.1 - 7.7e-43 146.6 0.0 2.3e-40 138.6 0.0 2.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain PH PF00169.29 CEP12990.1 - 1.1e-08 35.5 0.0 5.9e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 PH domain LRR_6 PF13516.6 CEP12990.1 - 0.0062 16.5 0.1 0.0062 16.5 0.1 8.6 9 0 0 9 9 9 1 Leucine Rich repeat Herpes_UL25 PF01499.16 CEP12990.1 - 0.017 13.7 1.3 0.037 12.6 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family GPW_gp25 PF04965.14 CEP12990.1 - 0.045 13.5 1.9 4 7.3 0.3 2.5 2 0 0 2 2 2 0 Gene 25-like lysozyme PH_16 PF17838.1 CEP12990.1 - 0.065 13.1 0.5 2.7 7.9 0.0 3.2 3 0 0 3 3 3 0 PH domain SCF PF02404.15 CEP12991.1 - 0.026 13.9 0.3 0.049 13.0 0.3 1.4 1 0 0 1 1 1 0 Stem cell factor Stealth_CR4 PF17103.5 CEP12991.1 - 0.069 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 DUF4730 PF15873.5 CEP12991.1 - 0.47 10.8 3.1 0.28 11.5 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) TMEM171 PF15471.6 CEP12991.1 - 1 8.3 6.6 0.48 9.4 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 AJAP1_PANP_C PF15298.6 CEP12991.1 - 2.1 8.5 29.6 36 4.5 24.9 3.0 2 1 0 2 2 2 0 AJAP1/PANP C-terminus DUF3074 PF11274.8 CEP12992.1 - 6e-26 91.6 0.0 9.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) mCpol PF18182.1 CEP12992.1 - 0.016 15.6 0.4 0.027 14.8 0.4 1.5 1 1 0 1 1 1 0 minimal CRISPR polymerase domain Methyltransf_16 PF10294.9 CEP12993.1 - 6.4e-21 74.8 0.0 1.2e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase HLH PF00010.26 CEP12993.1 - 9.8e-18 63.9 2.6 9.8e-18 63.9 2.6 2.2 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain PrmA PF06325.13 CEP12993.1 - 8.9e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CEP12993.1 - 3.5e-06 26.9 0.0 6.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP12993.1 - 9.3e-06 26.3 0.0 2.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP12993.1 - 6.4e-05 23.6 0.3 0.00018 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP12993.1 - 0.00014 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP12993.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CEP12993.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CEP12993.1 - 0.0073 16.9 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain T2SSG PF08334.11 CEP12993.1 - 0.027 14.5 0.1 0.061 13.4 0.1 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G ATG16 PF08614.11 CEP12993.1 - 0.033 14.4 6.0 0.063 13.5 6.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LSM PF01423.22 CEP12995.1 - 0.02 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 LSM domain Nup35_RRM_2 PF14605.6 CEP12996.1 - 0.0024 17.9 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Cas9_C PF18525.1 CEP12996.1 - 0.023 14.9 2.6 0.3 11.3 0.2 3.0 3 1 0 3 3 3 0 Cas9 C-terminal domain DUF3484 PF11983.8 CEP12996.1 - 0.16 13.1 7.3 1.6 9.9 0.3 3.1 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Arg_tRNA_synt_N PF03485.16 CEP12996.1 - 0.32 11.6 6.9 6.8 7.3 0.1 3.1 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain Mis14 PF08641.12 CEP12996.1 - 0.44 10.9 18.5 0.85 9.9 2.3 3.2 3 0 0 3 3 3 0 Kinetochore protein Mis14 like G-alpha PF00503.20 CEP12997.1 - 8.1e-120 400.2 6.7 9.3e-120 400.0 6.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP12997.1 - 3.6e-16 59.1 3.5 9.7e-12 44.7 0.3 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP12997.1 - 0.00064 19.2 5.2 0.0083 15.5 0.2 2.7 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP12997.1 - 0.0047 17.0 0.0 3.2 7.9 0.0 2.5 1 1 1 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 CEP12997.1 - 0.0065 16.7 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 CEP12997.1 - 0.021 14.6 0.0 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger AAA_29 PF13555.6 CEP12997.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CEP12997.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 CEP12997.1 - 0.066 12.3 0.2 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain MRP-L47 PF06984.13 CEP12998.1 - 5.3e-28 97.0 2.8 7.9e-28 96.4 2.8 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CEP12998.1 - 8.5e-07 28.8 1.7 1.5e-06 28.0 1.7 1.4 1 0 0 1 1 1 1 Ribosomal L29 protein Glyco_hydro_63 PF03200.16 CEP12999.1 - 1e-169 565.4 1.3 1.7e-168 561.4 1.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CEP12999.1 - 2e-72 244.0 0.0 3.7e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CEP12999.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Aldedh PF00171.22 CEP13000.1 - 1.3e-130 436.1 0.0 1.8e-130 435.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family XRN_M PF17846.1 CEP13000.1 - 3.1e-99 332.9 5.0 5.7e-99 332.0 5.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CEP13000.1 - 5.6e-85 284.6 0.0 1.3e-84 283.4 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 CEP13000.1 - 1.8e-64 217.1 2.4 3.3e-64 216.2 0.0 2.3 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CEP13000.1 - 3.5e-23 81.5 2.4 3.6e-23 81.4 0.2 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 CEP13000.1 - 5.4e-19 68.2 0.7 4.2e-18 65.4 0.0 3.0 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain LuxC PF05893.14 CEP13000.1 - 0.045 12.8 0.0 0.17 10.9 0.0 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Chs7 PF12271.8 CEP13002.1 - 4e-92 308.6 27.1 2.4e-84 283.1 22.3 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone DUF2070 PF09843.9 CEP13002.1 - 2.3 6.4 14.8 2.9 6.1 14.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DSPc PF00782.20 CEP13003.1 - 2e-33 115.0 0.0 2.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP13003.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CEP13003.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Pkinase PF00069.25 CEP13004.1 - 2.2e-67 227.2 0.0 2.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13004.1 - 1.2e-28 100.1 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13004.1 - 8.5e-07 28.6 0.2 0.00016 21.1 0.1 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 CEP13004.1 - 0.00082 19.0 0.2 0.00082 19.0 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 CEP13004.1 - 0.0046 16.3 0.2 0.0073 15.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP13004.1 - 0.027 13.4 0.0 0.064 12.2 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CEP13004.1 - 0.15 12.0 0.2 0.37 10.7 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family P16-Arc PF04699.14 CEP13005.1 - 4.5e-52 176.5 0.0 5e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CEP13005.1 - 0.00099 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family AMP-binding PF00501.28 CEP13006.1 - 1.6e-87 293.8 0.1 3.1e-87 292.9 0.1 1.4 1 1 0 1 1 1 1 AMP-binding enzyme DUF1517 PF07466.11 CEP13007.1 - 0.045 13.9 1.1 0.056 13.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) MFS_1 PF07690.16 CEP13009.1 - 1e-22 80.6 43.7 7.7e-19 67.8 26.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily HMG_CoA_synt_C PF08540.10 CEP13010.1 - 1.1e-100 336.9 3.9 1.6e-100 336.4 3.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CEP13010.1 - 4.7e-87 290.3 0.3 7.7e-87 289.6 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 CEP13010.1 - 0.027 14.7 0.2 4 7.7 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Guanylate_cyc_2 PF09778.9 CEP13011.1 - 2.8e-57 193.5 0.6 1.2e-55 188.1 0.6 2.0 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 CEP13011.1 - 2.5e-10 41.1 0.1 5.2e-09 36.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 CEP13011.1 - 9.1e-05 22.3 0.0 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 1 Peptidase C39 family Peptidase_C70 PF12385.8 CEP13011.1 - 0.0011 18.9 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Phytochelatin PF05023.14 CEP13011.1 - 0.079 12.2 0.1 0.35 10.0 0.1 1.8 1 1 0 1 1 1 0 Phytochelatin synthase Pkinase PF00069.25 CEP13012.1 - 4e-41 141.1 0.0 6.1e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13012.1 - 7.9e-27 94.2 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP13012.1 - 0.044 12.5 1.2 0.072 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 CEP13012.1 - 0.099 11.6 0.0 0.099 11.6 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CEP13012.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIF1 PF05970.14 CEP13013.1 - 3.8e-43 148.1 0.0 5.6e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CEP13013.1 - 1.2e-20 74.6 0.9 8.9e-19 68.4 0.9 2.5 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CEP13013.1 - 4.6e-08 33.0 0.0 7.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEP13013.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CEP13013.1 - 0.022 15.1 0.0 0.057 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CEP13013.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 CEP13013.1 - 0.11 12.8 0.0 2 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEP13013.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DPBB_1 PF03330.18 CEP13015.1 - 2.8e-09 37.1 0.0 5.5e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase Vmethyltransf_C PF08456.10 CEP13015.1 - 0.059 12.9 0.2 0.071 12.7 0.2 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Med25_NR-box PF11244.8 CEP13015.1 - 0.077 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Zn_clus PF00172.18 CEP13016.1 - 0.01 15.9 16.1 0.017 15.2 16.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2854 PF11016.8 CEP13016.1 - 0.17 11.8 1.7 0.36 10.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2854) Glyco_hydro_9 PF00759.19 CEP13017.1 - 5.3e-60 204.0 6.9 6.4e-60 203.7 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.19 CEP13018.1 - 2.8e-36 125.8 0.2 3.1e-36 125.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FGGY_C PF02782.16 CEP13019.1 - 2e-70 236.6 0.8 1.3e-69 233.9 0.5 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CEP13019.1 - 1.6e-51 175.2 0.1 2.4e-51 174.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DPBB_1 PF03330.18 CEP13020.1 - 1.3e-10 41.4 0.0 4.3e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP13020.1 - 0.00016 21.5 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Barwin family ChapFlgA PF13144.6 CEP13020.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation MIF PF01187.18 CEP13021.1 - 2.1e-13 50.6 0.0 2.2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CEP13021.1 - 0.0027 17.6 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Tautomerase enzyme PIP49_C PF12260.8 CEP13021.1 - 0.064 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 STELLO PF03385.17 CEP13021.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 STELLO glycosyltransferases CAMSAP_CC1 PF17095.5 CEP13022.1 - 0.066 13.1 0.5 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF2559 PF10832.8 CEP13022.1 - 0.12 12.5 0.6 0.86 9.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) DUF5542 PF17696.1 CEP13022.1 - 0.16 12.1 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5542) FAR1 PF03101.15 CEP13023.1 - 9.5e-06 26.2 2.1 1.5e-05 25.6 2.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain BrkDBD PF09607.10 CEP13023.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Glyco_hydro_18 PF00704.28 CEP13024.1 - 2.2e-80 270.7 0.1 2.5e-80 270.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 VTC PF09359.10 CEP13025.1 - 7.5e-78 261.7 0.0 1.2e-77 261.0 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CEP13025.1 - 4.2e-13 49.5 3.1 8.2e-13 48.6 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP13025.1 - 5.7e-12 46.3 2.0 2.6e-08 34.2 0.1 2.3 1 1 1 2 2 2 2 SPX domain Metal_CEHH PF14455.6 CEP13025.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted metal binding domain VTC PF09359.10 CEP13026.1 - 5.5e-83 278.5 0.0 1.7e-82 277.0 0.0 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 CEP13026.1 - 2e-11 44.2 4.0 2e-11 44.2 4.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP13026.1 - 0.0011 19.0 2.8 0.0011 19.0 2.8 3.9 2 1 2 4 4 4 2 SPX domain Glycos_transf_4 PF00953.21 CEP13026.1 - 0.029 14.4 2.4 0.049 13.6 2.4 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 HEAT_EZ PF13513.6 CEP13027.1 - 1.5e-28 98.8 7.5 2.7e-13 50.1 0.0 10.0 8 3 3 11 11 11 4 HEAT-like repeat HEAT PF02985.22 CEP13027.1 - 1.9e-24 83.6 8.8 0.00054 20.0 0.0 9.2 9 0 0 9 9 8 6 HEAT repeat HEAT_2 PF13646.6 CEP13027.1 - 6e-17 61.8 0.2 0.00011 22.5 0.0 6.5 5 1 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 CEP13027.1 - 8.7e-16 58.4 1.6 0.00028 21.0 0.1 4.7 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CEP13027.1 - 2.7e-12 46.4 0.0 1.5e-11 44.0 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.23 CEP13027.1 - 7e-10 38.6 3.8 0.38 10.8 0.1 7.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CEP13027.1 - 1.6e-09 38.2 0.0 0.013 16.1 0.0 5.7 4 2 3 7 7 6 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CEP13027.1 - 2.3e-06 26.5 1.1 0.00019 20.2 0.1 3.3 3 1 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 CEP13027.1 - 5.1e-06 26.2 0.2 1.2 8.7 0.0 4.8 4 2 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 CEP13027.1 - 4.6e-05 22.7 3.6 0.027 13.6 0.1 4.1 2 2 0 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.12 CEP13027.1 - 0.00028 20.7 4.4 0.069 12.9 0.2 4.8 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 CEP13027.1 - 0.00044 20.1 0.1 13 5.8 0.0 5.4 5 1 1 6 6 6 0 Domain of unknown function (DUF3437) ParcG PF10274.9 CEP13027.1 - 0.00062 19.9 4.2 1 9.5 0.1 4.4 6 0 0 6 6 5 2 Parkin co-regulated protein RasGEF_N_2 PF14663.6 CEP13027.1 - 0.0031 17.9 0.7 0.14 12.5 0.0 3.8 5 0 0 5 5 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain UNC45-central PF11701.8 CEP13027.1 - 0.0068 16.4 4.0 0.018 15.0 0.6 3.5 4 1 1 5 5 5 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 CEP13027.1 - 0.0087 16.2 0.7 17 5.6 0.0 4.4 3 2 2 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 CEP13027.1 - 0.0094 16.2 0.0 1.1 9.7 0.0 3.9 5 0 0 5 5 4 1 TAF6 C-terminal HEAT repeat domain Proteasom_PSMB PF10508.9 CEP13027.1 - 0.014 14.0 0.0 0.046 12.2 0.0 1.9 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.14 CEP13027.1 - 0.017 14.5 3.3 0.43 9.8 0.1 3.2 4 0 0 4 4 4 0 V-ATPase subunit H TIP120 PF08623.10 CEP13027.1 - 0.02 14.6 0.0 3.2 7.5 0.0 3.7 4 0 0 4 4 3 0 TATA-binding protein interacting (TIP20) XPC-binding PF09280.11 CEP13027.1 - 0.23 11.2 8.7 0.18 11.6 0.2 4.7 4 0 0 4 4 4 0 XPC-binding domain RNA_pol_3_Rpc31 PF11705.8 CEP13027.1 - 8.6 6.5 14.0 13 5.9 14.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Brix PF04427.18 CEP13028.1 - 6.9e-27 94.8 0.1 1.3e-26 93.9 0.1 1.4 1 0 0 1 1 1 1 Brix domain TBPIP_N PF15517.6 CEP13028.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 TBP-interacting protein N-terminus RIO1 PF01163.22 CEP13028.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Rrn6 PF10214.9 CEP13028.1 - 0.83 8.1 5.0 1.1 7.7 5.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pox_Ag35 PF03286.14 CEP13028.1 - 2.1 8.1 12.9 3.1 7.5 12.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PIN_8 PF18476.1 CEP13028.1 - 4.2 7.2 11.9 2.1 8.2 6.0 2.2 2 0 0 2 2 2 0 PIN like domain EF_TS PF00889.19 CEP13029.1 - 1.6e-32 112.8 0.3 1.7e-25 89.9 0.0 2.5 2 1 1 3 3 3 2 Elongation factor TS HBS1_N PF08938.10 CEP13029.1 - 0.023 15.0 0.1 0.073 13.4 0.1 1.9 1 0 0 1 1 1 0 HBS1 N-terminus Ribosomal_L7Ae PF01248.26 CEP13030.1 - 2.9e-26 91.0 0.0 3.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Thioredox_DsbH PF03190.15 CEP13031.1 - 3e-70 235.4 0.1 5.1e-70 234.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CEP13031.1 - 1.2e-09 38.3 0.0 2.8e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 CEP13031.1 - 0.00013 21.2 0.3 0.00031 20.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CEP13031.1 - 0.00042 18.9 0.0 0.00083 18.0 0.0 1.4 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Thioredoxin_2 PF13098.6 CEP13031.1 - 0.024 15.1 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF702 PF05142.12 CEP13032.1 - 7.9 6.9 7.1 1.9 9.0 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4476 PF14771.6 CEP13033.1 - 0.02 15.2 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) Syntaxin_2 PF14523.6 CEP13034.1 - 0.059 13.7 0.1 0.092 13.1 0.1 1.4 1 1 0 1 1 1 0 Syntaxin-like protein LOH1CR12 PF10158.9 CEP13034.1 - 0.14 12.1 0.5 2.7 8.0 0.0 2.1 1 1 1 2 2 2 0 Tumour suppressor protein DDE_3 PF13358.6 CEP13035.1 - 4.9e-17 62.0 0.1 8.2e-16 58.1 0.0 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease DUF1031 PF06275.11 CEP13038.1 - 0.093 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) CCP_MauG PF03150.14 CEP13039.1 - 0.0085 16.8 0.1 0.0095 16.6 0.1 1.1 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase LEM PF03020.15 CEP13041.1 - 0.26 10.9 6.5 0.68 9.6 0.6 2.5 2 0 0 2 2 2 0 LEM domain PIF1 PF05970.14 CEP13044.1 - 6.6e-36 124.2 0.2 1.1e-19 70.8 0.3 3.9 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CEP13044.1 - 6e-22 78.8 0.0 1.2e-21 77.8 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RabGAP-TBC PF00566.18 CEP13047.1 - 5e-35 121.1 21.0 9e-35 120.3 14.8 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CEP13047.1 - 6.3e-10 38.8 0.4 1.2e-09 37.9 0.4 1.4 1 0 0 1 1 1 1 Rab-binding domain (RBD) DAO PF01266.24 CEP13048.1 - 6.7e-54 183.8 0.0 8.6e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CEP13048.1 - 3.6e-44 149.7 0.1 9.5e-44 148.3 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CEP13048.1 - 5.9e-09 35.5 2.6 8.7e-08 31.7 2.6 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CEP13048.1 - 1.6e-06 27.7 1.3 0.00011 21.7 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CEP13048.1 - 1.1e-05 24.7 0.3 0.04 13.0 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CEP13048.1 - 2.3e-05 23.8 1.7 0.0052 16.1 0.1 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP13048.1 - 0.0016 18.7 0.6 0.008 16.4 0.4 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CEP13048.1 - 0.0092 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CEP13048.1 - 0.026 13.8 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEP13048.1 - 0.027 13.5 0.0 0.54 9.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 CEP13048.1 - 0.038 14.5 1.0 0.18 12.4 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP13048.1 - 0.13 10.9 0.3 0.23 10.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CEP13048.1 - 0.14 11.3 0.3 0.33 10.1 0.3 1.8 1 1 0 1 1 1 0 FAD binding domain Ank_2 PF12796.7 CEP13049.1 - 1.1e-10 41.9 0.2 2.3e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP13049.1 - 1.3e-09 38.4 0.1 3.1e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP13049.1 - 2.2e-07 30.6 1.3 1.3e-05 25.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CEP13049.1 - 3.9e-07 30.2 0.3 1.4e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEP13049.1 - 8.8e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ribosomal_L27A PF00828.19 CEP13050.1 - 1.6e-20 74.1 0.8 1.6e-20 74.0 0.3 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A WD40 PF00400.32 CEP13051.1 - 2e-50 167.7 21.3 4.6e-09 36.7 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CEP13051.1 - 1.7e-44 151.2 1.0 6.9e-44 149.2 0.6 2.3 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CEP13051.1 - 1.6e-11 44.3 0.1 0.025 14.9 0.0 5.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP13051.1 - 1.1e-06 28.2 0.2 0.037 13.4 0.0 4.0 3 2 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 CEP13051.1 - 5.4e-06 25.3 9.9 0.27 9.8 0.0 4.5 3 2 1 5 5 5 3 Nucleoporin Nup120/160 LisH PF08513.11 CEP13051.1 - 3.9e-05 23.5 1.2 0.00011 22.0 0.1 2.4 2 0 0 2 2 2 1 LisH RAB3GAP2_N PF14655.6 CEP13051.1 - 0.026 13.8 0.1 20 4.3 0.0 3.6 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SNF2_N PF00176.23 CEP13053.1 - 6e-46 156.8 1.7 4.2e-45 154.0 0.1 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP13053.1 - 1.8e-13 50.8 0.1 1.2e-12 48.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP13053.1 - 6e-08 32.9 0.5 1.4e-06 28.5 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP13053.1 - 2.4e-05 23.7 0.9 3.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CEP13053.1 - 0.0028 17.5 0.1 0.012 15.4 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEP13053.1 - 0.0091 15.7 1.9 8.1 6.0 0.0 3.6 3 0 0 3 3 3 2 SWI2/SNF2 ATPase AAA_14 PF13173.6 CEP13053.1 - 0.02 14.9 0.0 0.087 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_34 PF13872.6 CEP13053.1 - 0.023 13.6 0.0 0.27 10.1 0.0 2.1 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Ser_hydrolase PF06821.13 CEP13053.1 - 0.048 13.5 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase LRAT PF04970.13 CEP13053.1 - 0.14 12.4 0.7 0.75 10.1 0.1 2.5 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Phage_coat PF09063.10 CEP13054.1 - 0.066 13.2 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage PP7 coat protein SOAR PF16533.5 CEP13054.1 - 0.067 13.2 1.1 0.69 9.9 0.2 2.1 1 1 1 2 2 2 0 STIM1 Orai1-activating region Androgen_recep PF02166.16 CEP13055.1 - 0.0097 14.8 2.4 0.014 14.3 2.4 1.2 1 0 0 1 1 1 1 Androgen receptor Herpes_TK PF00693.18 CEP13055.1 - 0.05 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DUF2967 PF11179.8 CEP13055.1 - 0.076 11.1 2.0 0.098 10.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MULE PF10551.9 CEP13056.1 - 0.00012 22.4 0.9 0.00022 21.5 0.2 1.8 2 0 0 2 2 2 1 MULE transposase domain LVIVD PF08309.11 CEP13058.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat Abhydrolase_3 PF07859.13 CEP13059.1 - 1.8e-23 83.5 6.3 2.9e-18 66.5 0.0 3.8 2 1 1 4 4 4 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP13059.1 - 9.1e-07 28.1 0.0 0.00039 19.4 0.0 2.2 1 1 1 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 CEP13059.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CEP13059.1 - 0.15 11.5 0.2 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mago-bind PF09282.10 CEP13060.1 - 1.5e-15 56.7 0.8 3.2e-15 55.7 0.8 1.6 1 0 0 1 1 1 1 Mago binding rRNA_proc-arch PF13234.6 CEP13060.1 - 0.00065 19.7 1.3 0.00069 19.6 1.3 1.0 1 0 0 1 1 1 1 rRNA-processing arch domain Uds1 PF15456.6 CEP13061.1 - 0.011 15.9 7.6 0.014 15.6 1.6 3.0 1 1 2 3 3 3 0 Up-regulated During Septation KxDL PF10241.9 CEP13061.1 - 0.015 15.6 1.3 0.015 15.6 1.3 4.1 1 1 4 5 5 5 0 Uncharacterized conserved protein DUF3287 PF11690.8 CEP13061.1 - 0.034 13.9 0.6 0.034 13.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Glyco_hydro_49 PF03718.13 CEP13061.1 - 0.061 13.3 1.4 0.13 12.3 0.8 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 TSC22 PF01166.18 CEP13061.1 - 1.2 9.5 9.6 12 6.3 0.5 3.5 2 1 1 3 3 3 0 TSC-22/dip/bun family Ax_dynein_light PF10211.9 CEP13061.1 - 4.8 7.1 24.8 1.4 8.8 1.6 3.6 1 1 3 4 4 4 0 Axonemal dynein light chain Tropomyosin_1 PF12718.7 CEP13061.1 - 7.6 6.7 28.5 0.11 12.7 8.0 3.5 1 1 3 4 4 4 0 Tropomyosin like HSF_DNA-bind PF00447.17 CEP13062.1 - 6.3e-33 113.3 1.0 6.3e-33 113.3 1.0 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding PI_PP_I PF18363.1 CEP13062.1 - 0.075 13.2 1.9 0.28 11.4 0.4 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Tmemb_cc2 PF10267.9 CEP13062.1 - 0.34 10.0 14.6 0.6 9.2 0.4 2.5 2 2 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein YabA PF06156.13 CEP13062.1 - 3.5 8.3 4.9 2.6 8.7 0.6 2.7 2 1 0 2 2 2 0 Initiation control protein YabA VWA_N PF08399.11 CEP13064.1 - 0.098 13.1 0.1 0.45 11.0 0.1 1.9 1 1 1 2 2 2 0 VWA N-terminal RVT_1 PF00078.27 CEP13066.1 - 1.7e-23 83.3 0.0 4.5e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP13066.1 - 2.6e-07 30.4 0.0 7.2e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP13066.1 - 0.00074 19.3 1.2 0.0024 17.7 1.2 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Ribosomal_L41 PF05162.13 CEP13066.1 - 0.78 9.9 3.1 1.6 8.8 3.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L41 DUF3829 PF12889.7 CEP13067.1 - 0.00036 20.1 0.2 0.00061 19.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Myb_DNA-bind_4 PF13837.6 CEP13067.1 - 0.025 14.9 0.1 0.063 13.7 0.1 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Adaptin_binding PF10199.9 CEP13068.1 - 0.00041 20.9 0.7 0.00041 20.9 0.7 1.6 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 Androgen_recep PF02166.16 CEP13068.1 - 0.025 13.4 0.4 0.037 12.9 0.4 1.2 1 0 0 1 1 1 0 Androgen receptor Gastrin PF00918.17 CEP13068.1 - 0.3 12.0 4.1 12 6.9 0.1 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Goodbye PF17109.5 CEP13068.1 - 5.4 7.5 6.3 2.7 8.5 0.3 2.7 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain RT_RNaseH_2 PF17919.1 CEP13073.1 - 1.1e-30 105.6 0.0 2e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP13073.1 - 3.4e-30 104.4 0.0 5.3e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP13073.1 - 3.4e-14 52.9 0.3 1.1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GST_N_5 PF18485.1 CEP13073.1 - 0.19 12.1 0.2 0.67 10.3 0.1 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain RT_RNaseH PF17917.1 CEP13074.1 - 1.7e-35 121.5 0.4 5.3e-35 119.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP13074.1 - 1.1e-27 97.0 0.1 2.7e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP13074.1 - 5.3e-23 80.9 0.5 1.8e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP13075.1 - 5.2e-20 71.9 0.0 1.2e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP13075.1 - 2.3e-08 34.0 4.8 0.0038 17.3 0.0 2.5 2 0 0 2 2 2 2 Integrase zinc binding domain rve PF00665.26 CEP13075.1 - 0.00021 21.5 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CEP13075.1 - 0.055 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Exo_endo_phos_2 PF14529.6 CEP13076.1 - 3.6e-05 23.6 0.1 8.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP13076.1 - 0.00019 21.0 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phage_int_SAM_4 PF13495.6 CEP13077.1 - 0.042 14.3 0.0 0.071 13.6 0.0 1.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HEAT_2 PF13646.6 CEP13078.1 - 0.00078 19.8 0.4 0.0011 19.4 0.4 1.3 1 0 0 1 1 1 1 HEAT repeats Plant_NMP1 PF06694.11 CEP13079.1 - 0.046 12.8 0.0 0.05 12.7 0.0 1.0 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Chromo PF00385.24 CEP13080.1 - 0.27 11.2 2.5 0.22 11.5 0.5 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cid2 PF09774.9 CEP13081.1 - 8.7e-20 71.7 7.6 1.5e-17 64.5 7.6 2.4 1 1 0 1 1 1 1 Caffeine-induced death protein 2 PRANC PF09372.10 CEP13081.1 - 0.035 14.4 0.1 0.078 13.3 0.1 1.7 1 1 0 1 1 1 0 PRANC domain LMWSLP_N PF12211.8 CEP13081.1 - 0.057 13.1 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal ATP-synt_ab PF00006.25 CEP13082.1 - 1e-71 241.0 0.0 1.5e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CEP13082.1 - 2.6e-48 163.5 0.1 4.3e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CEP13082.1 - 4.5e-20 71.9 0.6 1.2e-19 70.6 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PC-Esterase PF13839.6 CEP13083.1 - 6.6e-29 101.5 0.0 1.1e-28 100.7 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Erp_C PF06780.11 CEP13083.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Erp protein C-terminus PMR5N PF14416.6 CEP13083.1 - 0.13 12.6 6.5 0.076 13.3 2.4 2.6 2 1 0 2 2 2 0 PMR5 N terminal Domain Anp1 PF03452.14 CEP13084.1 - 9.3e-83 277.7 0.2 1.2e-82 277.3 0.2 1.1 1 0 0 1 1 1 1 Anp1 SgrT PF15894.5 CEP13084.1 - 0.07 13.1 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT SWIRM PF04433.17 CEP13085.1 - 1.2e-10 41.6 0.0 4.4e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain ATG22 PF11700.8 CEP13086.1 - 9.7e-96 321.3 21.7 1.7e-95 320.5 21.7 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CEP13086.1 - 1.9e-12 46.8 40.8 2.2e-07 30.1 10.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2730 PF10805.8 CEP13086.1 - 0.22 11.6 0.1 0.58 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) GPR_Gpa2_C PF11970.8 CEP13086.1 - 3.1 7.9 5.5 1.7 8.8 0.3 2.9 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Vps5 PF09325.10 CEP13087.1 - 4.6e-15 55.8 10.9 9.3e-11 41.7 1.4 2.2 1 1 1 2 2 2 2 Vps5 C terminal like PX PF00787.24 CEP13087.1 - 2.5e-14 53.2 0.1 1e-11 44.8 0.0 2.7 2 0 0 2 2 2 2 PX domain Sec34 PF04136.15 CEP13087.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.6 2 1 1 3 3 3 0 Sec34-like family NPV_P10 PF05531.12 CEP13087.1 - 0.75 10.3 3.4 3.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Holin_BhlA PF10960.8 CEP13087.1 - 1.1 9.3 3.7 4.5 7.3 0.3 2.9 2 0 0 2 2 2 0 BhlA holin family DUF16 PF01519.16 CEP13087.1 - 1.9 9.0 5.8 23 5.5 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 CEP13087.1 - 2.7 8.0 10.5 2.1 8.4 2.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.27 CEP13088.1 - 6.5e-12 45.4 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP13089.1 - 1.1e-12 48.2 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CEP13093.1 - 6.5e-18 64.9 0.1 1.4e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13093.1 - 1.6e-14 53.8 0.3 2.2e-10 40.5 0.1 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP13093.1 - 6.1e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13093.1 - 9.5e-06 25.6 0.1 2.1e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CEP13093.1 - 0.033 14.8 0.0 0.085 13.4 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Dsl1_C PF11989.8 CEP13093.1 - 0.11 12.2 0.5 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal zf-CCHC PF00098.23 CEP13094.1 - 0.1 12.7 2.1 0.1 12.7 2.1 2.4 3 0 0 3 3 3 0 Zinc knuckle XPG_I PF00867.18 CEP13095.1 - 0.02 15.2 0.0 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 XPG I-region ADPrib_exo_Tox PF03496.14 CEP13095.1 - 0.024 14.0 1.3 0.037 13.4 0.3 1.7 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme DNA_repr_REX1B PF14966.6 CEP13095.1 - 0.055 14.1 0.3 0.32 11.7 0.1 2.2 2 0 0 2 2 2 0 DNA repair REX1-B Mannitol_dh PF01232.23 CEP13095.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Pkinase PF00069.25 CEP13096.1 - 2.9e-52 177.6 0.1 9.4e-52 176.0 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13096.1 - 7.3e-22 77.9 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CEP13096.1 - 0.0067 16.1 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Ofd1_CTDD PF10637.9 CEP13096.1 - 0.022 14.1 4.6 0.24 10.7 0.1 2.5 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term APH PF01636.23 CEP13096.1 - 0.054 13.4 0.2 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 CEP13097.1 - 1.3e-11 44.8 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP13097.1 - 1.1e-07 32.1 0.0 3.2e-07 30.7 0.0 1.6 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP13097.1 - 1.8e-07 31.2 0.0 3.1e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP13097.1 - 3.8e-06 26.8 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP13097.1 - 0.00012 22.2 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP13097.1 - 0.0062 16.7 0.1 0.0082 16.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4385 PF14328.6 CEP13097.1 - 0.054 13.6 0.4 0.082 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) GET2 PF08690.10 CEP13098.1 - 0.29 10.8 2.7 0.33 10.6 2.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Redoxin PF08534.10 CEP13101.1 - 1.2e-34 119.2 0.0 2.1e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEP13101.1 - 6.1e-15 55.2 0.0 1.8e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family O-FucT PF10250.9 CEP13101.1 - 1.1e-07 31.8 0.3 0.012 15.3 0.0 3.2 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase WD40 PF00400.32 CEP13102.1 - 0.023 15.6 2.3 7.6 7.6 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF726 PF05277.12 CEP13103.1 - 1.9e-86 290.1 0.0 2.7e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF900 PF05990.12 CEP13103.1 - 0.097 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2207 PF09972.9 CEP13103.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 CEP13103.1 - 2.2 8.3 10.4 0.52 10.4 5.9 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-H2C2_2 PF13465.6 CEP13104.1 - 7.3e-17 61.0 30.3 2.4e-08 34.0 0.5 5.6 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP13104.1 - 1.6e-10 40.8 32.9 1.4e-05 25.3 4.8 6.1 6 1 0 6 6 6 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 CEP13104.1 - 6.5e-08 33.1 20.2 0.0059 17.2 0.5 5.3 1 1 4 5 5 5 3 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CEP13104.1 - 0.00011 22.7 45.2 0.0067 17.2 3.5 7.3 7 0 0 7 7 6 2 C2H2-type zinc finger zf_UBZ PF18439.1 CEP13104.1 - 0.0088 15.6 2.9 0.96 9.1 0.1 2.8 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger C1_4 PF07975.12 CEP13104.1 - 0.023 14.9 3.4 0.023 14.9 3.4 3.4 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 CEP13104.1 - 0.028 14.2 2.7 0.028 14.2 2.7 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CEP13104.1 - 0.058 13.7 11.7 0.07 13.4 0.5 3.2 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CEP13104.1 - 0.08 13.0 0.4 0.08 13.0 0.4 5.0 5 0 0 5 5 4 0 C2H2-type zinc finger Yippee-Mis18 PF03226.14 CEP13104.1 - 0.15 12.3 3.5 6.1 7.1 3.6 2.7 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-H2C2_5 PF13909.6 CEP13104.1 - 0.82 9.5 0.1 0.82 9.5 0.1 5.5 6 0 0 6 6 5 0 C2H2-type zinc-finger domain RRN9 PF10680.9 CEP13104.1 - 7 7.0 0.0 7 7.0 0.0 3.0 3 1 0 3 3 3 0 RNA polymerase I specific transcription initiation factor UQ_con PF00179.26 CEP13105.1 - 8.1e-22 77.4 0.1 1.3e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP13105.1 - 0.035 14.4 0.9 0.061 13.6 0.1 1.8 2 0 0 2 2 2 0 RWD domain Ca_hom_mod PF14798.6 CEP13105.1 - 0.073 12.2 0.4 0.11 11.6 0.4 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Zip PF02535.22 CEP13105.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hydrolase_4 PF12146.8 CEP13106.1 - 2.1e-56 190.9 0.1 2.5e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP13106.1 - 2.1e-13 51.4 0.0 2.5e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEP13106.1 - 6.5e-12 45.6 0.5 5.6e-11 42.6 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEP13106.1 - 0.0023 17.4 0.2 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CEP13106.1 - 0.044 13.6 0.9 0.31 10.8 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3089 PF11288.8 CEP13106.1 - 0.045 13.3 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) HMMR_C PF15908.5 CEP13106.1 - 0.058 13.7 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF1749 PF08538.10 CEP13106.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LCAT PF02450.15 CEP13106.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 CEP13106.1 - 0.14 12.2 0.2 1.3 9.1 0.1 2.3 2 1 0 2 2 2 0 Thioesterase domain Oxysterol_BP PF01237.18 CEP13107.1 - 1.6e-114 382.6 0.2 7.8e-114 380.4 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CEP13107.1 - 5.4e-12 45.8 0.3 2.3e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CEP13107.1 - 2.2e-05 24.9 0.4 0.00028 21.4 0.1 2.5 2 0 0 2 2 2 1 PH domain GOLD_2 PF13897.6 CEP13107.1 - 0.012 16.1 0.1 0.32 11.5 0.0 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Iso_dh PF00180.20 CEP13110.1 - 0.025 13.8 0.5 0.039 13.1 0.5 1.3 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase ZapA PF05164.13 CEP13110.1 - 0.13 12.7 0.3 0.4 11.1 0.1 1.8 2 0 0 2 2 2 0 Cell division protein ZapA Ketoacyl-synt_2 PF13723.6 CEP13112.1 - 1.1 8.8 7.0 1.7 8.3 7.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Helitron_like_N PF14214.6 CEP13113.1 - 1.6e-11 44.7 0.4 1.6e-10 41.5 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Exo_endo_phos_2 PF14529.6 CEP13115.1 - 8.1e-06 25.7 0.4 3.4e-05 23.7 0.4 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF383 PF04063.14 CEP13115.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) CASP_C PF08172.12 CEP13116.1 - 0.003 17.0 1.4 0.0034 16.8 1.4 1.2 1 0 0 1 1 1 1 CASP C terminal Sld5 PF05916.11 CEP13117.1 - 0.069 13.6 0.1 0.23 11.9 0.1 1.9 1 0 0 1 1 1 0 GINS complex protein Anp1 PF03452.14 CEP13118.1 - 4e-93 311.6 0.3 6.3e-93 311.0 0.3 1.3 1 0 0 1 1 1 1 Anp1 GATase_4 PF13230.6 CEP13118.1 - 8.7e-17 60.9 0.1 7.2e-16 57.9 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CEP13118.1 - 6.7e-09 36.0 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glycos_transf_2 PF00535.26 CEP13118.1 - 0.002 17.9 1.1 0.058 13.2 1.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 NAD_Gly3P_dh_N PF01210.23 CEP13120.1 - 1.7e-52 177.6 0.5 2.8e-52 176.8 0.2 1.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CEP13120.1 - 3.5e-47 160.2 0.3 7.3e-47 159.2 0.1 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CEP13120.1 - 0.0012 19.4 0.4 0.93 10.1 0.1 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Sigma70_r1_1 PF03979.14 CEP13120.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 RRM_1 PF00076.22 CEP13121.1 - 4.7e-15 55.2 0.0 8.5e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.17 CEP13122.1 - 5.9e-33 113.4 2.5 5.9e-33 113.4 2.5 2.4 2 1 0 2 2 2 1 HSF-type DNA-binding AAA_24 PF13479.6 CEP13122.1 - 0.0019 17.9 1.1 0.0031 17.3 1.1 1.3 1 0 0 1 1 1 1 AAA domain TraB PF01963.17 CEP13122.1 - 0.0058 16.6 0.6 0.0088 16.0 0.6 1.2 1 0 0 1 1 1 1 TraB family Cep57_CLD_2 PF14197.6 CEP13122.1 - 0.0058 16.7 2.8 0.012 15.7 2.8 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 CortBP2 PF09727.9 CEP13122.1 - 0.031 14.2 7.4 0.048 13.6 7.4 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 DHR10 PF18595.1 CEP13122.1 - 0.046 13.8 4.9 0.08 13.0 4.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CLZ PF16526.5 CEP13122.1 - 0.069 13.5 2.0 0.15 12.5 2.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HD_assoc PF13286.6 CEP13122.1 - 1.4 9.5 5.1 4.2 8.0 5.1 1.8 1 0 0 1 1 1 0 Phosphohydrolase-associated domain PEX11 PF05648.14 CEP13123.1 - 2.8e-20 72.8 0.2 3.8e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MARVEL PF01284.23 CEP13125.1 - 4.5e-12 46.2 12.1 7e-12 45.6 12.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain LapA_dom PF06305.11 CEP13125.1 - 0.13 12.1 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fasciclin PF02469.22 CEP13126.1 - 3.5e-28 98.4 15.3 8.2e-23 81.0 2.3 4.0 3 1 0 3 3 3 3 Fasciclin domain Oxidored_FMN PF00724.20 CEP13127.1 - 4.1e-68 230.2 0.0 4.8e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4449 PF14613.6 CEP13128.1 - 5.6e-11 42.8 0.3 5.6e-11 42.8 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RPN6_N PF18055.1 CEP13128.1 - 4.9 7.5 7.6 13 6.1 0.9 3.6 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain ACBP PF00887.19 CEP13129.1 - 5.1e-27 93.9 0.1 1.3e-26 92.6 0.1 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein TCO89 PF10452.9 CEP13129.1 - 8.2e-08 31.7 7.0 8.2e-08 31.7 7.0 2.1 1 1 0 2 2 2 1 TORC1 subunit TCO89 ABC_tran_CTD PF16326.5 CEP13129.1 - 0.0036 17.5 1.3 0.15 12.4 0.4 3.0 2 0 0 2 2 2 1 ABC transporter C-terminal domain DUF2680 PF10925.8 CEP13129.1 - 0.0073 16.3 2.5 1.6 8.8 0.3 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2680) PBP1_TM PF14812.6 CEP13129.1 - 0.19 12.1 1.5 0.47 10.8 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF919 PF06034.11 CEP13129.1 - 0.27 11.1 3.3 18 5.3 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DivIC PF04977.15 CEP13129.1 - 0.53 10.1 3.1 1.8 8.4 3.1 1.9 1 0 0 1 1 1 0 Septum formation initiator WD40 PF00400.32 CEP13130.1 - 6.1e-42 140.8 19.0 1.8e-08 34.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13130.1 - 4.1e-16 59.0 0.0 0.00075 19.7 0.1 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP13130.1 - 0.0063 15.9 0.0 1.2 8.4 0.0 3.2 2 1 2 4 4 4 2 WD40-like domain eIF2A PF08662.11 CEP13130.1 - 0.0067 16.3 0.0 5 6.9 0.0 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP13130.1 - 0.021 13.8 1.2 1.5 7.7 0.4 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Phage_GP20 PF06810.11 CEP13130.1 - 0.067 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Nup160 PF11715.8 CEP13130.1 - 0.14 10.7 0.1 5.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 CEP13131.1 - 8.1e-19 67.2 0.8 1.9e-18 66.1 0.8 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP13131.1 - 1.1e-10 41.5 0.5 3.2e-08 33.6 0.1 2.7 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CEP13131.1 - 0.0001 21.9 0.1 0.00082 19.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RicinB_lectin_2 PF14200.6 CEP13132.1 - 2.2e-21 76.4 0.0 3.1e-09 37.4 0.0 3.2 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP13132.1 - 7.8e-14 52.0 0.0 5.3e-07 29.9 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain MgtE PF01769.16 CEP13133.1 - 1.2e-12 48.3 2.8 1.2e-12 48.3 2.8 1.7 2 0 0 2 2 2 1 Divalent cation transporter MgtE PF01769.16 CEP13134.1 - 7.7e-19 68.3 0.5 7.7e-19 68.3 0.5 1.4 2 0 0 2 2 2 1 Divalent cation transporter BCDHK_Adom3 PF10436.9 CEP13135.1 - 5e-43 146.8 0.0 8.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEP13135.1 - 8e-12 45.7 0.1 6e-11 42.8 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP13135.1 - 4.8e-08 32.9 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CEP13135.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain IBR PF01485.21 CEP13137.1 - 1.8e-22 79.3 41.6 3e-11 43.4 5.1 4.6 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CEP13137.1 - 2.4e-06 27.8 35.7 0.00024 21.3 4.5 3.9 3 0 0 3 3 3 3 Ring finger domain zf-RING_UBOX PF13445.6 CEP13137.1 - 3.7e-06 26.9 34.2 5.5e-06 26.3 2.9 4.1 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP13137.1 - 9.6e-05 22.2 3.5 9.6e-05 22.2 3.5 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP13137.1 - 0.0013 18.6 2.8 0.0013 18.6 2.8 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP13137.1 - 0.0015 18.4 34.7 0.0028 17.5 3.1 4.5 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP13137.1 - 0.0061 16.7 1.0 0.0061 16.7 1.0 5.0 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CEP13137.1 - 0.022 14.7 5.8 0.022 14.7 5.8 3.5 3 0 0 3 3 3 0 zinc-RING finger domain DUF3685 PF12452.8 CEP13137.1 - 0.4 10.4 2.1 0.71 9.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF3824 PF12868.7 CEP13138.1 - 9.4e-06 26.4 6.2 0.97 10.1 0.7 3.5 2 1 1 3 3 3 3 Domain of unknwon function (DUF3824) Acetyltransf_1 PF00583.25 CEP13139.1 - 2e-06 28.0 0.3 5.6e-05 23.3 0.3 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP13139.1 - 0.0015 18.9 0.0 0.71 10.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP13139.1 - 0.018 15.0 0.1 0.93 9.4 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TPR_1 PF00515.28 CEP13140.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.18 CEP13140.1 - 0.0047 17.0 15.8 0.0055 16.8 13.3 2.3 2 0 0 2 2 2 1 MYND finger TPR_2 PF07719.17 CEP13140.1 - 0.033 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP13140.1 - 0.056 13.7 0.2 0.32 11.3 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat PET117 PF15786.5 CEP13140.1 - 0.092 13.0 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Aminotran_5 PF00266.19 CEP13141.1 - 9.1e-31 107.1 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V zf-RING_7 PF02591.15 CEP13141.1 - 0.15 12.3 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain AAA PF00004.29 CEP13142.1 - 5.3e-64 214.6 0.0 1.3e-43 148.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEP13142.1 - 3.4e-10 40.6 2.2 0.008 16.6 0.0 4.5 4 1 0 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 CEP13142.1 - 6e-10 38.8 1.1 6.7e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain TsaE PF02367.17 CEP13142.1 - 7.7e-07 29.1 0.4 0.07 13.1 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CEP13142.1 - 9.2e-07 28.7 0.0 0.0023 17.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CEP13142.1 - 1.1e-06 28.9 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEP13142.1 - 1.5e-06 28.7 0.1 0.02 15.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CEP13142.1 - 1.8e-06 28.3 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEP13142.1 - 3.5e-06 27.3 1.3 0.04 14.2 0.1 3.7 3 1 1 4 4 4 2 AAA domain RNA_helicase PF00910.22 CEP13142.1 - 4.6e-06 27.0 0.0 0.062 13.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 CEP13142.1 - 1.5e-05 24.6 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 CEP13142.1 - 2.1e-05 24.6 0.0 0.35 10.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CEP13142.1 - 2.8e-05 24.1 0.0 0.019 15.0 0.0 3.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CEP13142.1 - 7.5e-05 22.0 0.0 0.11 11.7 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain TIP49 PF06068.13 CEP13142.1 - 0.00019 20.8 0.0 0.016 14.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CEP13142.1 - 0.00055 19.7 0.0 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CEP13142.1 - 0.00066 19.7 2.2 0.13 12.2 0.0 2.9 3 1 1 4 4 2 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 CEP13142.1 - 0.00072 19.7 0.0 0.027 14.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 CEP13142.1 - 0.00078 19.1 0.2 0.025 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEP13142.1 - 0.00081 18.8 0.1 0.034 13.5 0.1 2.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CEP13142.1 - 0.001 19.0 0.1 1.4 8.8 0.1 2.8 3 0 0 3 3 2 2 NACHT domain AAA_17 PF13207.6 CEP13142.1 - 0.0018 18.7 0.0 1.9 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 CEP13142.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CEP13142.1 - 0.0022 17.8 0.1 0.16 11.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEP13142.1 - 0.003 16.8 0.0 3 6.9 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.6 CEP13142.1 - 0.0043 16.9 1.1 2.1 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CEP13142.1 - 0.0054 16.7 0.0 3.4 7.5 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 CEP13142.1 - 0.014 15.1 0.4 4.9 6.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CEP13142.1 - 0.017 15.6 0.7 3 8.3 0.0 3.3 3 0 0 3 3 3 0 ABC transporter ATPase PF06745.13 CEP13142.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 1 0 KaiC Rad17 PF03215.15 CEP13142.1 - 0.027 14.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 CEP13142.1 - 0.031 14.0 0.0 0.82 9.3 0.0 3.0 4 0 0 4 4 3 0 Sigma-54 interaction domain Vps4_C PF09336.10 CEP13142.1 - 0.036 14.0 0.1 1.5 8.8 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 CEP13142.1 - 0.08 12.8 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CEP13142.1 - 0.091 12.5 1.8 7.3 6.4 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain PhoH PF02562.16 CEP13142.1 - 0.13 11.6 0.1 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 CEP13142.1 - 0.14 12.5 0.1 4.5 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 CEP13143.1 - 2.1e-17 61.8 1.8 0.00073 19.5 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEP13143.1 - 5.8e-13 48.1 1.2 0.00018 21.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP13143.1 - 5.1e-11 42.9 3.0 0.055 14.0 0.0 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP13143.1 - 1.2e-10 40.8 2.6 0.0019 18.3 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP13143.1 - 3.1e-09 36.9 0.1 1 10.4 0.0 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP13143.1 - 7.5e-08 32.6 3.8 0.007 16.6 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP13143.1 - 8.5e-08 31.8 1.2 0.0092 15.7 0.4 4.0 5 0 0 5 5 5 2 TPR repeat TPR_15 PF13429.6 CEP13143.1 - 6.7e-07 28.8 3.9 0.0011 18.3 0.6 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP13143.1 - 8.3e-07 29.1 0.7 0.043 14.1 0.4 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CEP13143.1 - 1.3e-06 29.0 0.1 0.36 11.5 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP13143.1 - 1.6e-05 24.9 1.0 0.17 12.3 0.0 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP13143.1 - 0.00029 21.3 7.3 0.64 10.8 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP13143.1 - 0.00094 19.1 2.3 4.5 7.5 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP13143.1 - 0.0015 18.6 0.5 0.17 12.0 0.0 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP13143.1 - 0.24 11.4 5.2 3.6 7.6 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Hexokinase_2 PF03727.16 CEP13144.1 - 2.9e-87 292.1 0.0 4.4e-87 291.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP13144.1 - 4e-73 245.6 0.2 6.9e-73 244.8 0.2 1.4 1 0 0 1 1 1 1 Hexokinase Bac_DNA_binding PF00216.21 CEP13144.1 - 0.0042 17.2 0.0 0.08 13.1 0.0 2.6 2 0 0 2 2 2 1 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 CEP13144.1 - 0.02 14.7 0.1 0.06 13.2 0.1 1.8 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF2564 PF10819.8 CEP13144.1 - 0.025 15.0 0.4 0.073 13.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Peptidase_S8 PF00082.22 CEP13145.1 - 6.2e-51 173.4 2.1 1.5e-50 172.1 2.1 1.7 1 1 0 1 1 1 1 Subtilase family PA PF02225.22 CEP13145.1 - 7.9e-16 57.9 2.4 2.8e-15 56.1 2.4 2.0 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 CEP13145.1 - 4.8e-14 53.0 1.5 2.3e-13 50.8 1.5 2.3 1 0 0 1 1 1 1 Fn3-like domain NUMOD3 PF07460.11 CEP13146.1 - 0.11 12.7 1.0 9.6 6.5 0.6 2.4 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) LNS2 PF08235.13 CEP13148.1 - 3.9e-103 343.8 0.0 5.8e-103 343.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CEP13148.1 - 2.4e-40 136.6 0.0 4.3e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CEP13148.1 - 5.7e-18 64.9 0.1 1.5e-17 63.5 0.1 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain WRNPLPNID PF15017.6 CEP13148.1 - 0.038 14.9 0.6 0.038 14.9 0.6 5.0 5 1 0 5 5 5 0 Putative WW-binding domain and destruction box HSP70 PF00012.20 CEP13149.1 - 3.5e-253 841.2 10.8 4.3e-253 840.9 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP13149.1 - 6.5e-17 61.3 0.1 1.2e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CEP13149.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4449 PF14613.6 CEP13149.1 - 0.097 12.8 2.4 2.4 8.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) Speriolin_N PF15058.6 CEP13149.1 - 0.13 12.3 0.2 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Speriolin N terminus Actin PF00022.19 CEP13150.1 - 9.4e-43 146.3 0.0 2e-42 145.2 0.0 1.4 1 1 0 1 1 1 1 Actin Asp_protease_2 PF13650.6 CEP13151.1 - 0.003 18.2 0.0 0.0055 17.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP13151.1 - 0.027 15.0 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Myb_DNA-bind_6 PF13921.6 CEP13153.1 - 7.5e-05 22.9 0.2 0.00025 21.2 0.0 2.0 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP13153.1 - 0.00097 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med3 PF11593.8 CEP13153.1 - 0.12 11.6 5.8 0.15 11.2 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DSHCT PF08148.12 CEP13154.1 - 2.6e-42 144.3 0.5 1.7e-40 138.4 0.5 2.6 1 1 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CEP13154.1 - 9.4e-30 104.4 0.0 1.4e-29 103.9 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CEP13154.1 - 4.7e-07 30.1 0.0 1.6e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Ski2_N PF17911.1 CEP13155.1 - 1.1e-38 132.1 0.0 2e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 CEP13155.1 - 3.1e-18 66.1 0.0 5.4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CEP13155.1 - 4.1e-06 26.9 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP13155.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.20 CEP13156.1 - 3.9e-10 39.7 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Cation_efflux PF01545.21 CEP13157.1 - 7.5e-11 42.1 6.3 1.1e-10 41.6 6.3 1.3 1 0 0 1 1 1 1 Cation efflux family Presenilin PF01080.17 CEP13157.1 - 0.045 12.5 1.3 1.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 CEP13157.1 - 1.6 7.2 17.6 2.3 6.7 17.6 1.1 1 0 0 1 1 1 0 Macoilin family zf-AN1 PF01428.16 CEP13158.1 - 2.4e-18 66.0 24.9 1.9e-10 40.7 7.8 3.3 2 1 1 3 3 3 2 AN1-like Zinc finger zf-C3HC PF07967.13 CEP13158.1 - 0.43 10.6 9.0 0.97 9.5 2.7 2.4 1 1 1 2 2 2 0 C3HC zinc finger-like zinc_ribbon_4 PF13717.6 CEP13158.1 - 0.75 9.8 7.0 0.89 9.5 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CEP13158.1 - 0.93 9.8 24.0 20 5.5 19.2 3.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_L28 PF00830.19 CEP13159.1 - 6.1e-21 74.4 0.8 6.1e-21 74.4 0.8 1.5 2 0 0 2 2 2 1 Ribosomal L28 family Chromo_shadow PF01393.19 CEP13160.1 - 9.5e-15 54.4 4.6 4.2e-12 46.0 0.9 2.6 2 1 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CEP13160.1 - 8e-09 35.3 1.1 8e-09 35.3 1.1 2.5 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3970 PF13113.6 CEP13167.1 - 0.18 12.0 1.4 0.46 10.7 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) SNF2_N PF00176.23 CEP13169.1 - 1.3e-57 195.1 0.1 1.3e-57 195.1 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP13169.1 - 7.2e-17 61.7 0.0 7.2e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 CEP13169.1 - 2.2e-15 56.3 3.4 1.8e-10 40.5 0.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-binding PF00249.31 CEP13169.1 - 0.0067 16.6 0.1 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ipi1_N PF12333.8 CEP13170.1 - 0.078 13.6 0.2 0.26 11.9 0.1 1.9 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation RVT_1 PF00078.27 CEP13171.1 - 1.8e-15 57.1 0.1 2.7e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1241 PF06840.11 CEP13171.1 - 0.0014 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DDE_3 PF13358.6 CEP13172.1 - 2.3e-21 76.1 0.0 1.4e-18 67.0 0.0 2.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_1 PF00126.27 CEP13172.1 - 0.025 14.5 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family VirD1 PF07328.11 CEP13172.1 - 0.048 13.6 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Polyketide_cyc PF03364.20 CEP13174.1 - 6.3e-08 32.9 0.3 3.4e-07 30.5 0.3 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CEP13174.1 - 2.1e-07 31.3 0.0 3.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HisK_sensor PF18698.1 CEP13174.1 - 0.44 10.9 5.2 0.63 10.4 2.2 2.4 2 0 0 2 2 2 0 Histidine kinase sensor domain DNA_pol_A_exo1 PF01612.20 CEP13176.1 - 6e-08 32.6 0.0 1.1e-06 28.5 0.0 2.0 1 1 1 2 2 2 2 3'-5' exonuclease CotH PF08757.11 CEP13177.1 - 3.5e-37 128.6 0.1 5.4e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 CotH kinase protein Iron_transport PF10634.9 CEP13177.1 - 0.047 13.9 0.2 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Fe2+ transport protein Fra10Ac1 PF09725.9 CEP13178.1 - 3.3e-48 162.9 5.0 7.6e-48 161.7 5.0 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 WD40 PF00400.32 CEP13178.1 - 1.8e-14 53.9 7.8 3.4e-05 24.5 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CEP13178.1 - 8.3e-11 42.0 0.0 3.4e-09 36.8 0.0 3.1 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CEP13178.1 - 2.7e-07 30.8 2.0 0.0023 18.2 0.4 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP13178.1 - 0.00011 22.2 0.2 0.003 17.5 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SID-1_RNA_chan PF13965.6 CEP13178.1 - 0.092 11.1 2.4 0.16 10.3 2.4 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pkinase PF00069.25 CEP13179.1 - 2.2e-57 194.4 0.0 2.5e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13179.1 - 8.2e-20 71.2 0.0 5.9e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13179.1 - 0.00029 20.3 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP13179.1 - 0.0027 17.1 0.1 0.0038 16.6 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP13179.1 - 0.051 13.5 0.1 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP13179.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GDA1_CD39 PF01150.17 CEP13180.1 - 2e-100 336.4 0.0 2.6e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CEP13180.1 - 0.0027 17.2 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Fungal_trans PF04082.18 CEP13181.1 - 3.2e-06 26.4 1.4 1.7e-05 24.0 0.6 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain DHR10 PF18595.1 CEP13182.1 - 0.0054 16.8 0.2 0.0054 16.8 0.2 2.0 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain DUF3450 PF11932.8 CEP13182.1 - 0.086 12.1 0.1 0.086 12.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 CEP13182.1 - 0.2 11.8 6.5 0.26 11.5 6.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 CEP13182.1 - 0.28 11.3 11.3 0.33 11.0 11.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Topoisom_I_N PF02919.15 CEP13182.1 - 0.65 9.5 5.4 0.72 9.3 5.4 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CSG2 PF16965.5 CEP13182.1 - 2.8 6.8 4.8 3.3 6.6 4.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2560 PF10834.8 CEP13184.1 - 0.093 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) PEGSRP PF07623.11 CEP13184.1 - 0.2 11.5 0.2 0.39 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) RhoGAP PF00620.27 CEP13185.1 - 1.6e-15 57.3 1.1 5.2e-15 55.6 1.1 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CEP13185.1 - 1.5e-07 31.6 0.0 6.5e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PRC PF05239.16 CEP13185.1 - 0.017 15.2 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 PRC-barrel domain MFS_1 PF07690.16 CEP13186.1 - 3.1e-54 184.2 22.7 6.9e-54 183.1 20.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP13186.1 - 2.5e-15 56.3 3.9 2.5e-15 56.3 3.9 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CEP13186.1 - 4.7e-10 38.5 1.8 4.7e-10 38.5 1.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CEP13186.1 - 6.4e-07 28.0 10.3 1.5e-06 26.8 4.8 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family LapA_dom PF06305.11 CEP13186.1 - 0.053 13.3 10.0 4.9 7.0 0.1 4.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain HLH PF00010.26 CEP13187.1 - 7e-14 51.5 1.2 2e-13 50.1 1.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.15 CEP13187.1 - 0.05 13.7 2.8 0.32 11.1 0.1 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain zf-C2H2 PF00096.26 CEP13188.1 - 4.5e-10 39.4 11.6 5.6e-06 26.5 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP13188.1 - 6e-07 29.6 16.3 1.3e-06 28.6 4.0 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP13188.1 - 2.8e-06 27.7 11.5 0.0046 17.7 0.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEP13188.1 - 0.0056 16.8 3.7 0.01 16.0 3.7 1.4 1 0 0 1 1 1 1 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CEP13188.1 - 1.7 8.4 13.0 1.9 8.3 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain LMBR1 PF04791.16 CEP13189.1 - 1.2e-17 64.0 13.9 5.9e-15 55.2 4.0 2.2 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF4534 PF15049.6 CEP13189.1 - 0.0046 16.7 0.3 0.059 13.1 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4534) GWT1 PF06423.12 CEP13189.1 - 2.5 8.2 15.4 0.15 12.2 5.0 3.5 2 2 0 2 2 2 0 GWT1 Dopey_N PF04118.14 CEP13190.1 - 1e-109 366.4 7.5 5.7e-109 363.9 0.1 3.0 3 0 0 3 3 3 2 Dopey, N-terminal HTH_45 PF14947.6 CEP13190.1 - 0.19 11.7 0.7 1.6 8.8 0.2 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix PIN_6 PF17146.4 CEP13191.1 - 4.7e-30 103.9 0.0 1e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CEP13191.1 - 4.4e-29 100.4 2.3 8.2e-29 99.6 2.3 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 CEP13191.1 - 0.058 13.4 1.0 0.13 12.3 1.0 1.5 1 0 0 1 1 1 0 Double zinc ribbon CoA_binding PF02629.19 CEP13191.1 - 0.07 13.8 0.1 0.27 11.9 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Zn-ribbon_8 PF09723.10 CEP13191.1 - 0.24 11.5 1.1 0.61 10.3 1.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 CEP13191.1 - 0.31 10.8 2.2 0.38 10.5 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 CEP13191.1 - 0.61 9.8 3.4 0.98 9.1 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 CEP13191.1 - 8.3 6.4 6.1 0.97 9.4 1.2 2.0 2 0 0 2 2 2 0 Nudix N-terminal Rad1 PF02144.16 CEP13192.1 - 2.7e-09 36.5 0.2 3.4e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AlaDh_PNT_N PF05222.15 CEP13193.1 - 4.8e-31 107.9 0.0 7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CEP13193.1 - 0.00076 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain EIIBC-GUT_N PF03612.14 CEP13193.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Glyco_hydro_20 PF00728.22 CEP13194.1 - 1.7e-104 350.0 0.7 2.2e-104 349.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CEP13194.1 - 3.3e-14 53.7 0.7 2.3e-12 47.7 0.1 2.7 2 1 1 3 3 3 2 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CEP13194.1 - 0.00036 21.3 0.1 0.014 16.2 0.1 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 YnfE PF17452.2 CEP13195.1 - 0.0076 16.5 3.4 0.0089 16.3 3.4 1.1 1 0 0 1 1 1 1 Uncharacterized YnfE-like RGS PF00615.19 CEP13196.1 - 5.2e-29 100.9 0.2 2.3e-28 98.8 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 CEP13196.1 - 1.9e-14 53.5 0.4 2.7e-08 33.7 0.1 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Lge1 PF11488.8 CEP13196.1 - 0.25 11.5 2.7 2.3 8.5 0.0 3.5 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 EF-hand_4 PF12763.7 CEP13197.1 - 3.8e-42 142.4 0.0 9.3e-16 57.7 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 CEP13197.1 - 7.7e-06 25.7 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 CEP13197.1 - 7.8e-06 25.1 0.0 1.1 9.0 0.0 4.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CEP13197.1 - 9.8e-06 25.9 0.0 0.092 13.2 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair Plasmodium_HRP PF05403.11 CEP13197.1 - 0.011 15.5 0.4 0.035 13.9 0.4 1.8 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) EF-hand_6 PF13405.6 CEP13197.1 - 0.016 15.1 0.4 18 5.6 0.1 4.1 4 0 0 4 4 4 0 EF-hand domain Clathrin_lg_ch PF01086.17 CEP13199.1 - 2.2e-45 155.5 9.0 2.9e-45 155.1 9.0 1.2 1 0 0 1 1 1 1 Clathrin light chain Methyltransf_16 PF10294.9 CEP13199.1 - 2.6e-24 85.9 0.0 4.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase 6PF2K PF01591.18 CEP13200.1 - 6.8e-48 162.9 0.0 1.1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP13200.1 - 8.7e-23 81.0 0.0 2.5e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NDC10_II PF16787.5 CEP13204.1 - 5.2e-11 42.2 0.0 6.2e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 ABC_membrane PF00664.23 CEP13205.1 - 8.5e-52 176.5 28.2 1.5e-33 116.6 6.9 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP13205.1 - 1.1e-48 165.2 0.0 8e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP13205.1 - 1.1e-11 44.6 0.6 0.00011 21.7 0.2 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CEP13205.1 - 5.4e-06 27.1 0.1 0.012 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CEP13205.1 - 7e-06 26.4 1.1 0.084 13.1 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CEP13205.1 - 7.2e-06 25.6 0.3 0.18 11.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 CEP13205.1 - 9.6e-06 24.8 0.0 0.0094 15.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 CEP13205.1 - 3.7e-05 23.4 0.1 0.046 13.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 CEP13205.1 - 8.9e-05 22.9 0.7 0.1 13.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEP13205.1 - 0.00013 22.2 2.7 0.21 11.8 0.1 3.7 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 CEP13205.1 - 0.00016 21.5 0.9 5.1 6.8 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 CEP13205.1 - 0.00037 20.7 1.3 0.048 13.7 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 CEP13205.1 - 0.0011 18.3 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family NB-ARC PF00931.22 CEP13205.1 - 0.0014 17.8 0.0 0.11 11.7 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 CEP13205.1 - 0.0019 18.1 0.1 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP13205.1 - 0.0027 17.8 0.2 0.3 11.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CEP13205.1 - 0.0053 16.4 1.4 0.083 12.5 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CEP13205.1 - 0.0076 16.1 0.8 6.9 6.4 0.0 3.3 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CEP13205.1 - 0.0088 16.6 0.3 4.9 7.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEP13205.1 - 0.013 15.4 3.4 3.5 7.5 0.2 3.2 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.6 CEP13205.1 - 0.016 14.9 0.1 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CEP13205.1 - 0.02 14.9 0.2 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 CEP13205.1 - 0.023 14.4 0.2 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP13205.1 - 0.023 15.1 0.8 9.4 6.7 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.17 CEP13205.1 - 0.029 14.2 1.2 15 5.3 0.3 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 CEP13205.1 - 0.03 14.1 0.4 5.3 6.8 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 CEP13205.1 - 0.048 13.7 0.7 7.7 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CEP13205.1 - 0.048 13.4 0.1 6.9 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 CEP13205.1 - 0.055 13.0 0.1 13 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 CEP13205.1 - 0.062 13.6 0.0 16 5.8 0.0 3.2 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.12 CEP13205.1 - 0.065 12.7 4.8 2.4 7.5 0.1 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein AAA_14 PF13173.6 CEP13205.1 - 0.12 12.4 0.1 12 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 CEP13205.1 - 0.16 12.4 1.0 10 6.5 0.2 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_pol_Rpb2_5 PF04567.17 CEP13205.1 - 0.17 12.5 0.1 37 5.0 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 ResIII PF04851.15 CEP13205.1 - 0.17 11.9 0.0 17 5.4 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 CEP13205.1 - 0.26 11.4 0.7 75 3.4 0.0 3.3 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 CEP13205.1 - 0.26 11.5 1.3 38 4.5 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CEP13205.1 - 0.68 9.8 2.4 41 4.0 0.1 3.4 3 0 0 3 3 3 0 NTPase MaoC_dehydratas PF01575.19 CEP13206.1 - 1e-27 96.2 0.0 3.8e-27 94.3 0.0 2.0 1 0 0 1 1 1 1 MaoC like domain SH3_1 PF00018.28 CEP13206.1 - 8.2e-25 86.2 4.4 1.1e-11 44.1 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CEP13206.1 - 1.4e-21 76.0 2.3 4.3e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 CEP13206.1 - 4e-20 71.8 0.0 9.8e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 CEP13206.1 - 6.6e-15 54.5 0.1 1e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain RT_RNaseH_2 PF17919.1 CEP13208.1 - 3.5e-33 113.6 0.0 8.7e-33 112.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP13208.1 - 2e-30 105.2 0.1 4.6e-30 104.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP13208.1 - 1.3e-19 70.6 0.0 2.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP13208.1 - 3e-14 53.2 0.0 7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13208.1 - 7.9e-13 48.3 0.4 1.6e-12 47.3 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP13208.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.17 CEP13209.1 - 1.2e-06 28.7 1.3 6.2e-06 26.4 0.1 2.1 1 1 1 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP13211.1 - 4e-09 37.0 0.1 7.8e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP13211.1 - 5.1e-09 36.6 0.0 9.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP13211.1 - 7.3e-05 22.6 0.1 0.00013 21.8 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP13211.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CEP13211.1 - 0.00048 19.7 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP13211.1 - 0.0049 16.9 2.7 0.0085 16.1 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CEP13211.1 - 0.0089 16.3 0.0 0.025 14.9 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 CEP13212.1 - 7e-37 125.9 0.0 1.7e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13212.1 - 1.1e-34 118.5 0.0 2.7e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP13212.1 - 8.2e-21 73.9 1.5 9.2e-21 73.7 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 CEP13212.1 - 9.1e-17 61.3 0.3 1.7e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 CEP13212.1 - 0.00066 19.8 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger UPF0262 PF06793.12 CEP13212.1 - 0.084 13.0 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) DUF569 PF04601.13 CEP13212.1 - 0.095 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF569) Chromo PF00385.24 CEP13213.1 - 7.3e-16 57.8 0.8 2.1e-15 56.3 0.8 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP13213.1 - 4.1e-09 36.7 0.0 1.4e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 CEP13213.1 - 0.022 14.7 0.6 0.061 13.2 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-CCHC PF00098.23 CEP13216.1 - 0.0083 16.2 11.3 0.0094 16.0 0.4 3.0 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CEP13216.1 - 0.014 15.3 0.4 0.014 15.3 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle SARG PF15385.6 CEP13216.1 - 0.034 13.4 4.9 0.038 13.2 4.9 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein zf-CCHC_6 PF15288.6 CEP13216.1 - 0.12 12.3 11.6 0.42 10.5 0.6 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP13216.1 - 0.24 11.1 7.2 0.68 9.7 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 CEP13219.1 - 6.2e-26 90.2 0.8 3.8e-17 62.0 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein RNase_PH PF01138.21 CEP13221.1 - 6.1e-38 130.3 0.0 9.3e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP13221.1 - 1.1e-08 35.0 0.1 1.8e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rax2 PF12768.7 CEP13222.1 - 1.5e-36 125.9 5.1 3.4e-35 121.5 0.5 3.7 3 0 0 3 3 3 2 Cortical protein marker for cell polarity SH3_9 PF14604.6 CEP13222.1 - 2.1e-09 37.1 0.2 4.2e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP13222.1 - 1.7e-08 33.9 0.3 1.7e-08 33.9 0.3 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CEP13222.1 - 1.1e-05 25.0 0.0 2.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF5122 PF17164.4 CEP13222.1 - 0.00084 19.6 12.1 13 6.2 0.1 7.7 7 0 0 7 7 7 1 Domain of unknown function (DUF5122) beta-propeller Kelch_6 PF13964.6 CEP13222.1 - 0.0083 16.4 6.0 2 8.8 0.0 5.5 5 0 0 5 5 5 1 Kelch motif Piwi PF02171.17 CEP13223.1 - 4.6e-92 308.5 0.1 6.9e-92 307.9 0.1 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CEP13223.1 - 9.1e-23 81.4 0.1 2.1e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CEP13223.1 - 3.5e-17 62.5 0.1 7.9e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CEP13223.1 - 3.7e-14 52.1 0.0 1.1e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CEP13223.1 - 1e-12 48.2 0.0 4.9e-12 46.0 0.0 2.3 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CEP13223.1 - 4.1e-09 36.6 0.0 1.5e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Mid domain of argonaute MULE PF10551.9 CEP13224.1 - 7.4e-06 26.3 0.6 1.9e-05 25.0 0.6 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 CEP13225.1 - 0.0028 18.3 0.5 0.0047 17.6 0.5 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Acetyltransf_1 PF00583.25 CEP13226.1 - 2.6e-15 56.7 0.0 2.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP13226.1 - 2.4e-08 34.0 0.1 3e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP13226.1 - 7.8e-08 32.6 0.0 1.1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP13226.1 - 3.4e-06 26.9 0.1 4.4e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP13226.1 - 0.0007 19.7 0.4 0.00084 19.4 0.4 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CEP13226.1 - 0.015 14.8 0.3 0.042 13.3 0.0 1.7 1 1 1 2 2 2 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CEP13226.1 - 0.019 15.7 0.0 0.022 15.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Xpo1 PF08389.12 CEP13227.1 - 3.5e-13 49.9 1.5 6.9e-12 45.7 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein Importin_rep PF18773.1 CEP13227.1 - 2e-10 40.2 0.1 4.6e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 CEP13227.1 - 2.5e-08 33.7 4.8 4.4e-08 32.9 3.5 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Kinesin PF00225.23 CEP13231.1 - 1.1e-100 336.9 0.2 1.1e-100 336.9 0.2 2.6 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP13231.1 - 1.1e-22 80.6 0.1 1.1e-22 80.6 0.1 3.5 3 0 0 3 3 3 1 Microtubule binding AAA_22 PF13401.6 CEP13231.1 - 1.1 9.5 12.7 1.5 9.1 0.0 5.0 5 0 0 5 5 5 0 AAA domain Aldedh PF00171.22 CEP13232.1 - 3.2e-18 65.5 6.4 1.9e-13 49.7 2.4 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CEP13232.1 - 0.00039 19.6 0.3 0.00081 18.5 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cu-oxidase PF00394.22 CEP13233.1 - 1.9e-29 102.8 0.1 8.8e-28 97.4 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEP13233.1 - 5.4e-28 97.4 1.1 1.3e-27 96.2 1.1 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEP13233.1 - 1.1e-22 80.3 12.0 3.6e-21 75.3 2.4 3.7 2 2 0 2 2 2 2 Multicopper oxidase Copper-bind PF00127.20 CEP13233.1 - 0.031 14.7 0.1 0.35 11.3 0.1 2.5 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family Mito_carr PF00153.27 CEP13234.1 - 1.1e-60 201.5 10.7 3.4e-21 75.0 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CEP13234.1 - 4.3e-18 65.5 1.2 1.2e-10 41.6 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP13234.1 - 1.8e-13 49.2 3.0 0.0012 18.7 0.3 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CEP13234.1 - 5.6e-13 47.4 3.1 1.4e-05 24.3 1.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CEP13234.1 - 2.5e-12 46.4 5.0 4.7e-07 29.5 1.0 4.1 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 CEP13234.1 - 4.4e-06 26.4 0.5 0.025 14.4 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 CEP13234.1 - 4.5e-05 22.7 2.6 0.0071 15.8 0.7 3.5 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 CEP13234.1 - 0.0089 16.3 0.0 0.7 10.2 0.0 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP13234.1 - 0.16 12.0 0.1 0.88 9.6 0.0 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Serine_protease PF18405.1 CEP13234.1 - 0.65 9.1 4.0 18 4.4 0.0 3.1 2 2 0 3 3 3 0 Gammaproteobacterial serine protease HTH_32 PF13565.6 CEP13237.1 - 4.5e-08 33.6 0.0 3e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CEP13237.1 - 1.1e-07 31.4 0.2 4e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 CEP13237.1 - 2.1e-07 30.8 0.2 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP13237.1 - 1.2e-06 28.6 0.0 9.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP13237.1 - 1.4e-06 28.2 0.2 0.00059 19.8 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 CEP13237.1 - 3.2e-06 27.2 0.0 0.073 13.3 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 CEP13237.1 - 0.0027 17.1 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 CEP13237.1 - 0.0063 16.8 2.7 0.011 16.0 0.0 2.4 3 0 0 3 3 3 1 Transposase LZ_Tnp_IS481 PF13011.6 CEP13237.1 - 0.013 16.0 0.1 0.077 13.5 0.1 2.1 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 Beta_helix PF13229.6 CEP13237.1 - 0.047 13.5 0.2 1.6 8.6 0.2 2.3 1 1 1 2 2 2 0 Right handed beta helix region HTH_36 PF13730.6 CEP13237.1 - 0.048 13.6 0.2 0.35 10.9 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 CEP13237.1 - 0.059 13.3 0.1 9.8 6.2 0.1 2.3 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 CEP13237.1 - 0.068 13.0 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CEP13237.1 - 0.069 12.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_30 PF13556.6 CEP13237.1 - 0.15 11.9 0.0 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Uds1 PF15456.6 CEP13238.1 - 7.5e-23 81.1 9.1 7.5e-23 81.1 9.1 7.5 6 1 3 9 9 9 2 Up-regulated During Septation DUF2935 PF11155.8 CEP13238.1 - 0.1 12.9 0.2 0.1 12.9 0.2 5.3 4 4 1 5 5 5 0 Domain of unknown function (DUF2935) NOT2_3_5 PF04153.18 CEP13239.1 - 7.5e-28 97.2 0.9 1.2e-27 96.5 0.9 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Mhr1 PF12829.7 CEP13240.1 - 4.3e-05 23.5 0.3 7.4e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Caudo_TAP PF02413.17 CEP13240.1 - 0.026 14.7 1.0 0.034 14.3 1.0 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK LigB PF02900.18 CEP13241.1 - 6.7e-36 123.7 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3128 PF11326.8 CEP13241.1 - 0.046 14.1 4.4 0.071 13.5 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) FAD_binding_6 PF00970.24 CEP13242.1 - 1.6e-33 115.0 0.0 2.5e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CEP13242.1 - 1.3e-32 112.7 0.0 1.8e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEP13242.1 - 2.8e-05 24.3 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Rhomboid PF01694.22 CEP13243.1 - 7.9e-24 84.4 7.9 1.2e-23 83.8 7.9 1.2 1 0 0 1 1 1 1 Rhomboid family PAT1 PF09770.9 CEP13244.1 - 0.0012 17.2 41.1 0.0012 17.2 41.1 1.5 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.15 CEP13244.1 - 0.0074 15.1 35.4 0.011 14.6 35.4 1.2 1 0 0 1 1 1 1 Caldesmon DUF3671 PF12420.8 CEP13244.1 - 0.12 12.4 1.0 1 9.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function Iron_permease PF04120.12 CEP13245.1 - 4.2 7.2 6.7 8.7 6.1 6.7 1.6 1 1 0 1 1 1 0 Low affinity iron permease NfI_DNAbd_pre-N PF10524.9 CEP13247.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus NfI_DNAbd_pre-N PF10524.9 CEP13248.1 - 0.055 13.4 0.2 0.096 12.6 0.2 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Ribosomal_L18A PF01775.17 CEP13249.1 - 1.5e-55 186.5 1.7 1.9e-55 186.1 1.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Stimulus_sens_1 PF13756.6 CEP13249.1 - 0.094 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain GATA PF00320.27 CEP13250.1 - 1.3e-09 37.4 6.2 3.3e-09 36.2 6.2 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.6 CEP13250.1 - 0.053 13.4 0.1 0.097 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arm-DNA-bind_2 PF12167.8 CEP13250.1 - 0.67 9.9 2.4 19 5.3 0.1 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain SAP130_C PF16014.5 CEP13252.1 - 3 6.8 6.2 3.6 6.6 6.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DASH_Dad2 PF08654.10 CEP13253.1 - 0.0098 16.3 0.2 0.034 14.5 0.2 1.9 1 0 0 1 1 1 1 DASH complex subunit Dad2 OmdA PF13376.6 CEP13253.1 - 2.3 8.3 7.5 1.4 9.0 0.3 3.8 4 0 0 4 4 4 0 Bacteriocin-protection, YdeI or OmpD-Associated Mucin PF01456.17 CEP13254.1 - 7 6.6 15.8 8.1 6.4 15.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1604 PF07713.13 CEP13255.1 - 1.2 9.0 5.9 2.3 8.1 5.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) Exo_endo_phos_2 PF14529.6 CEP13256.1 - 2.5e-15 56.4 1.3 2.5e-15 56.4 1.3 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP13256.1 - 0.0016 18.0 0.2 0.0028 17.2 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1281 PF06924.11 CEP13256.1 - 1.9 8.0 5.7 3.8 7.0 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) RVT_1 PF00078.27 CEP13257.1 - 4.8e-09 36.1 0.0 1.3e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1180 PF06679.12 CEP13258.1 - 0.0022 18.4 0.3 0.0022 18.4 0.3 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 CEP13258.1 - 0.067 14.1 1.0 0.22 12.4 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CEP13258.1 - 0.75 10.1 10.2 0.8 10.0 0.0 2.9 4 0 0 4 4 4 0 Orf78 (ac78) WD40 PF00400.32 CEP13259.1 - 0.015 16.1 0.2 17 6.5 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Ly49 PF08391.10 CEP13259.1 - 6.9 7.1 6.2 3.7 8.0 2.9 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Ank_2 PF12796.7 CEP13260.1 - 8.3e-19 68.0 0.1 2.8e-10 40.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP13260.1 - 2.7e-17 62.9 0.1 3.5e-06 27.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP13260.1 - 9.4e-17 60.9 0.1 5.5e-11 42.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP13260.1 - 2.1e-12 46.1 0.0 3e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEP13260.1 - 2.2e-12 46.8 0.0 2.2e-06 27.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat PK_C PF02887.16 CEP13260.1 - 0.045 14.0 0.0 0.23 11.7 0.0 1.9 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain LIM PF00412.22 CEP13261.1 - 1.4e-27 95.7 74.5 5.1e-09 36.2 8.5 5.9 5 1 0 5 5 5 5 LIM domain DUF5351 PF17302.2 CEP13261.1 - 0.2 11.9 0.3 0.2 11.9 0.3 4.1 5 0 0 5 5 5 0 Family of unknown function (DUF5351) KH_1 PF00013.29 CEP13262.1 - 1.5e-44 149.6 6.9 3.9e-17 61.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEP13262.1 - 6.3e-12 45.2 5.8 0.0054 16.5 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CEP13262.1 - 5.3e-08 32.6 1.9 0.34 10.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CEP13262.1 - 4.7e-05 23.4 5.9 0.11 12.7 0.1 3.6 4 0 0 4 4 4 2 NusA-like KH domain Kri1_C PF12936.7 CEP13263.1 - 4.4e-29 100.5 3.4 4.4e-29 100.5 3.4 3.9 3 2 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 CEP13263.1 - 2.9e-23 82.4 6.2 2.9e-23 82.4 6.2 5.3 5 1 0 5 5 5 1 KRI1-like family SURF1 PF02104.15 CEP13263.1 - 8.1 6.7 7.5 10 6.3 4.5 2.4 1 1 1 2 2 2 0 SURF1 family Pkinase PF00069.25 CEP13264.1 - 1.1e-51 175.8 0.0 1.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TB2_DP1_HVA22 PF03134.19 CEP13264.1 - 1.4e-30 105.0 6.5 1.4e-30 105.0 6.5 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Pkinase_Tyr PF07714.17 CEP13264.1 - 1.2e-27 96.9 0.0 1.8e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP13264.1 - 0.0038 16.6 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosom_S12_S23 PF00164.25 CEP13265.1 - 6e-51 170.9 0.8 7.4e-51 170.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Chitin_synth_2 PF03142.15 CEP13266.1 - 9.1e-271 899.0 0.0 1.3e-270 898.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP13266.1 - 3.6e-15 56.5 0.1 3.5e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP13266.1 - 3.4e-13 50.0 0.4 1.2e-12 48.2 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CEP13266.1 - 4.7e-05 22.9 0.0 0.01 15.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEP13266.1 - 0.015 15.1 0.0 0.074 12.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF3439 PF11921.8 CEP13266.1 - 0.99 9.4 7.2 3.4 7.7 7.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YEATS PF03366.16 CEP13267.1 - 1.5e-18 66.6 0.1 3.6e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 YEATS family SR-25 PF10500.9 CEP13267.1 - 0.014 15.0 6.2 0.019 14.6 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Senescence_reg PF04520.13 CEP13267.1 - 1 10.2 5.4 1.7 9.5 5.4 1.3 1 0 0 1 1 1 0 Senescence regulator E1-E2_ATPase PF00122.20 CEP13268.1 - 4.3e-45 153.5 3.3 4.3e-45 153.5 3.3 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CEP13268.1 - 1.8e-23 84.0 0.2 5.3e-23 82.4 0.1 1.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP13268.1 - 8.2e-14 51.0 0.0 3.7e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 CEP13268.1 - 0.0077 16.0 5.8 0.0077 16.0 5.8 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP13268.1 - 0.014 15.5 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP13268.1 - 0.025 14.3 0.1 0.061 13.0 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Perilipin PF03036.16 CEP13269.1 - 5.6e-06 25.6 18.6 0.00011 21.4 0.4 3.3 1 1 2 3 3 3 2 Perilipin family Apolipoprotein PF01442.18 CEP13269.1 - 0.011 15.6 22.6 0.036 13.9 7.4 3.6 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain DUF4735 PF15882.5 CEP13269.1 - 0.074 12.5 0.1 0.074 12.5 0.1 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4735) Picorna_P3A PF06363.11 CEP13269.1 - 0.15 12.0 0.4 17 5.4 0.0 2.9 2 1 0 2 2 2 0 Picornaviridae P3A protein Aldo_ket_red PF00248.21 CEP13270.1 - 3.2e-41 141.4 0.0 3.9e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 CEP13271.1 - 3.5e-24 84.7 1.7 7.6e-24 83.6 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CEP13271.1 - 1.7e-10 40.9 8.8 9.8e-10 38.5 3.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP13271.1 - 6.4e-08 32.7 3.1 6.4e-08 32.7 3.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CEP13271.1 - 5.6e-07 29.8 5.2 0.011 16.0 0.7 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEP13271.1 - 7.6e-05 23.2 3.0 0.32 12.0 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP13271.1 - 0.0041 17.5 6.4 1 9.9 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF1043 PF06295.12 CEP13271.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) zf-RVT PF13966.6 CEP13271.1 - 0.49 11.2 2.9 0.35 11.6 0.4 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-CpG_bind_C PF12269.8 CEP13271.1 - 0.51 10.1 20.5 1.6 8.5 4.4 2.9 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-C2H2_3rep PF18868.1 CEP13271.1 - 1.2 9.8 4.6 4.9 7.9 0.2 3.1 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats ELM2 PF01448.24 CEP13271.1 - 2.9 8.7 7.0 8.9 7.1 0.8 3.5 3 0 0 3 3 2 0 ELM2 domain UPF0767 PF15990.5 CEP13271.1 - 3.8 7.7 5.3 5 7.3 0.3 3.2 3 0 0 3 3 3 0 UPF0767 family VCBS PF13517.6 CEP13272.1 - 8.8e-30 103.1 18.6 2.4e-09 37.6 1.2 5.6 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CEP13272.1 - 4.3e-10 39.5 28.2 0.0037 17.4 0.5 7.3 7 0 0 7 7 7 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 CEP13272.1 - 3.6e-05 23.2 3.0 0.74 9.2 0.0 5.1 4 2 2 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region DUF4690 PF15756.5 CEP13272.1 - 0.033 14.8 1.5 0.3 11.7 0.4 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Dockerin_1 PF00404.18 CEP13272.1 - 0.044 14.0 3.3 9.7 6.5 0.0 4.5 5 0 0 5 5 5 0 Dockerin type I domain Ninjurin PF04923.12 CEP13272.1 - 0.047 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Ninjurin RrnaAD PF00398.20 CEP13273.1 - 5.1e-20 71.7 0.0 6.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase C2 PF00168.30 CEP13274.1 - 1.4e-09 38.2 0.2 5.2e-09 36.3 0.0 2.1 2 1 0 2 2 2 1 C2 domain RPOL_N PF14700.6 CEP13274.1 - 0.0072 15.7 4.7 0.011 15.2 4.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal HemX PF04375.14 CEP13274.1 - 0.0078 15.5 0.5 0.011 15.0 0.5 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase MctB PF11382.8 CEP13274.1 - 0.058 13.1 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF3042 PF11240.8 CEP13274.1 - 0.087 12.9 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF2282 PF10048.9 CEP13274.1 - 0.2 11.7 6.9 0.53 10.3 6.9 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) RR_TM4-6 PF06459.12 CEP13274.1 - 0.53 10.1 9.8 0.93 9.3 9.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MAP17 PF15807.5 CEP13274.1 - 0.55 10.5 7.0 1.8 8.8 7.0 2.0 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4407 PF14362.6 CEP13274.1 - 3.2 7.0 5.2 4.5 6.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 CEP13274.1 - 5.8 6.0 5.8 11 5.1 5.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CEP13274.1 - 6.9 5.3 10.5 10 4.8 10.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M24 PF00557.24 CEP13275.1 - 2.5e-17 63.3 0.0 3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Glycohydro_20b2 PF14845.6 CEP13275.1 - 0.026 15.2 0.6 0.048 14.3 0.2 1.8 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like DUF3825 PF12873.7 CEP13276.1 - 0.034 13.6 0.4 0.057 12.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) PUF PF00806.19 CEP13277.1 - 1e-59 195.0 16.2 8.5e-08 31.5 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNB PF00773.19 CEP13278.1 - 1.6e-103 346.5 0.2 3.1e-103 345.5 0.0 1.5 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CEP13278.1 - 3.4e-20 71.8 0.0 8.4e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEP13278.1 - 6.9e-19 68.0 0.1 2.2e-18 66.3 0.1 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CEP13278.1 - 9.3e-06 25.7 0.1 0.027 14.7 0.0 3.8 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 CEP13278.1 - 0.0007 19.2 0.1 0.0034 17.0 0.1 2.2 2 0 0 2 2 2 1 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 CEP13278.1 - 0.016 14.9 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CEP13278.1 - 0.081 12.9 0.1 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 S1 domain RasGEF PF00617.19 CEP13281.1 - 7.1e-14 52.4 0.0 1.4e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain PAM2 PF07145.15 CEP13281.1 - 0.0046 16.5 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region SSP160 PF06933.11 CEP13281.1 - 2.7 6.1 18.3 4.6 5.3 18.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Bromodomain PF00439.25 CEP13282.1 - 1.2e-21 76.6 0.2 1.2e-21 76.6 0.2 2.6 3 0 0 3 3 3 1 Bromodomain SWC7 PF17330.2 CEP13282.1 - 0.025 14.6 0.1 0.081 13.0 0.1 1.8 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Myb_DNA-binding PF00249.31 CEP13282.1 - 0.09 13.0 5.0 0.11 12.8 0.1 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain SNARE_assoc PF09335.11 CEP13283.1 - 8.8e-12 45.6 6.3 1.1e-11 45.3 5.4 1.6 1 1 0 1 1 1 1 SNARE associated Golgi protein PhoR PF11808.8 CEP13283.1 - 0.003 17.9 0.5 0.0099 16.3 0.1 2.0 2 0 0 2 2 2 1 Phosphate regulon sensor protein PhoR FAD_binding_1 PF00667.20 CEP13284.1 - 8.6e-64 215.1 0.0 1.5e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 CEP13284.1 - 1.2e-26 93.8 2.5 2.1e-26 93.1 2.5 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.21 CEP13284.1 - 8.5e-12 45.7 0.0 2.8e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CEP13284.1 - 7.3e-06 26.2 0.0 2.9e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 CEP13284.1 - 0.045 14.1 0.0 0.51 10.7 0.0 2.5 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain Transketolase_C PF02780.20 CEP13284.1 - 0.077 12.9 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain Mito_carr PF00153.27 CEP13285.1 - 9.5e-41 137.7 6.5 1.7e-15 56.7 0.2 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Nuc_deoxyri_tr2 PF15891.5 CEP13286.1 - 0.16 12.3 0.9 2.7 8.4 1.2 2.6 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like WD40 PF00400.32 CEP13286.1 - 0.21 12.5 3.7 1.1 10.2 0.2 3.5 2 1 1 3 3 3 0 WD domain, G-beta repeat ANAPC_CDC26 PF10471.9 CEP13286.1 - 9.6 7.1 48.2 0.16 12.8 14.6 5.6 5 1 0 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 MPC PF03650.13 CEP13287.1 - 5.8e-20 71.5 0.0 6.7e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Glyco_transf_49 PF13896.6 CEP13288.1 - 3.7e-23 82.4 0.2 1.3e-13 51.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl-transferase for dystroglycan Glyoxal_oxid_N PF07250.11 CEP13288.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Ceramidase PF05875.12 CEP13290.1 - 1.8e-49 168.5 21.1 2.5e-41 141.9 9.2 2.0 1 1 1 2 2 2 2 Ceramidase Gti1_Pac2 PF09729.9 CEP13291.1 - 1.6e-42 145.7 10.9 7.3e-38 130.5 0.3 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family Cullin PF00888.22 CEP13293.1 - 1.6e-11 43.6 0.1 1.1e-10 40.8 0.0 2.1 2 1 0 2 2 2 1 Cullin family Chitin_synth_2 PF03142.15 CEP13294.1 - 1.6e-279 927.9 0.8 2.2e-279 927.5 0.8 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP13294.1 - 1.3e-14 54.7 0.0 1.3e-12 48.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP13294.1 - 2.3e-11 44.0 3.3 6e-11 42.6 3.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP13294.1 - 5.1e-05 23.1 0.0 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP13294.1 - 0.01 15.3 0.0 0.057 12.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 BAR PF03114.18 CEP13295.1 - 3.6e-31 108.7 5.0 5.4e-31 108.1 5.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CEP13295.1 - 4.8e-14 51.7 0.1 9.8e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP13295.1 - 4.8e-11 42.3 0.1 4.8e-11 42.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CEP13295.1 - 7.5e-11 41.5 0.0 1.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PBP PF01161.20 CEP13295.1 - 0.013 15.8 0.6 5.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphatidylethanolamine-binding protein FAM76 PF16046.5 CEP13295.1 - 0.11 11.8 1.7 0.24 10.7 1.7 1.6 1 0 0 1 1 1 0 FAM76 protein Streptin-Immun PF11083.8 CEP13295.1 - 1.5 9.3 5.3 1.9 8.9 1.8 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Pex14_N PF04695.13 CEP13295.1 - 1.8 9.2 13.5 0.64 10.7 10.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4349 PF14257.6 CEP13295.1 - 1.9 7.9 6.5 1.5 8.2 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) DUF489 PF04356.12 CEP13295.1 - 2.6 8.0 7.6 6.9 6.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) UDPG_MGDP_dh_N PF03721.14 CEP13297.1 - 1.9e-64 216.7 0.1 3.8e-64 215.7 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 CEP13297.1 - 2.9e-35 120.9 0.5 1.9e-33 115.0 0.2 2.6 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CEP13297.1 - 7.6e-30 103.0 0.0 1.7e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain OTCace PF00185.24 CEP13297.1 - 0.003 17.6 0.1 0.34 11.0 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain NAD_binding_2 PF03446.15 CEP13297.1 - 0.009 16.2 0.0 0.22 11.7 0.0 2.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 CEP13297.1 - 0.01 15.8 0.1 0.39 10.7 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.23 CEP13297.1 - 0.017 15.2 0.9 5.9 7.0 0.0 3.2 2 2 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Isochorismatase PF00857.20 CEP13297.1 - 0.038 14.2 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Isochorismatase family 3HCDH_N PF02737.18 CEP13297.1 - 0.076 12.9 0.1 0.52 10.2 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Med18 PF09637.10 CEP13298.1 - 8.3e-23 81.5 0.0 2.9e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Glyoxalase PF00903.25 CEP13299.1 - 1.7e-21 76.7 1.6 1.4e-16 60.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CEP13299.1 - 2.5e-11 43.8 0.1 6.9e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 CEP13299.1 - 1.6e-07 31.6 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 CEP13299.1 - 4.4e-05 23.7 0.5 0.0098 16.0 0.1 2.9 3 1 0 3 3 3 2 Glyoxalase-like domain GDPD_2 PF13653.6 CEP13299.1 - 0.37 11.3 1.3 14 6.3 0.0 2.8 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Ribosomal_L35Ae PF01247.18 CEP13300.1 - 2.7e-42 142.8 0.7 3e-42 142.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CEP13300.1 - 0.0017 18.5 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 CEP13300.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Pkinase PF00069.25 CEP13301.1 - 4.8e-14 52.4 0.0 7.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13301.1 - 1.4e-08 34.3 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Tyr-DNA_phospho PF06087.12 CEP13302.1 - 4.4e-49 167.5 0.1 1.1e-48 166.3 0.1 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 CEP13302.1 - 4.3e-06 26.3 0.8 0.0025 17.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 CEP13302.1 - 2e-05 24.5 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain SDA1 PF05285.12 CEP13303.1 - 0.00011 21.7 21.3 0.00011 21.7 21.3 2.9 2 1 0 2 2 2 1 SDA1 WD40 PF00400.32 CEP13304.1 - 0.00014 22.6 6.0 2.3 9.2 0.4 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat TFIIB PF00382.19 CEP13305.1 - 1e-43 147.2 3.4 3.9e-23 81.3 1.6 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CEP13305.1 - 7.4e-15 54.2 0.6 1.7e-14 53.0 0.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CEP13305.1 - 0.0074 16.0 2.0 0.1 12.4 0.5 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CEP13305.1 - 0.011 15.9 1.0 0.093 12.8 0.1 2.3 2 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_5 PF01022.20 CEP13305.1 - 0.016 15.0 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Trp_repressor PF01371.19 CEP13305.1 - 0.057 13.5 0.1 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Trp repressor protein HTH_Tnp_ISL3 PF13542.6 CEP13305.1 - 0.089 12.2 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RB_B PF01857.20 CEP13305.1 - 0.11 12.6 3.1 0.15 12.1 1.2 2.0 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain LacI PF00356.21 CEP13305.1 - 0.19 11.5 0.4 0.52 10.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2039 PF10217.9 CEP13305.1 - 5.2 7.5 9.6 13 6.2 4.5 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Bromodomain PF00439.25 CEP13306.1 - 8.8e-17 61.0 1.1 2.3e-16 59.6 1.1 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CEP13306.1 - 1.4e-09 37.8 0.0 4.3e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated Tim17 PF02466.19 CEP13307.1 - 2.5e-32 111.6 6.6 3.1e-32 111.3 6.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RAB3GAP2_N PF14655.6 CEP13308.1 - 3.4e-106 356.0 0.0 7.7e-106 354.8 0.0 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TPR_14 PF13428.6 CEP13308.1 - 0.00086 19.9 0.8 1.6 9.8 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Lsm_interact PF05391.11 CEP13308.1 - 0.0031 16.9 0.9 0.01 15.3 0.9 2.0 1 0 0 1 1 1 1 Lsm interaction motif TPR_17 PF13431.6 CEP13308.1 - 0.016 15.5 0.8 0.77 10.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP13308.1 - 0.021 15.5 2.1 1.4 9.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Dus PF01207.17 CEP13309.1 - 7.3e-75 251.9 0.0 1.1e-74 251.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 CEP13309.1 - 0.0023 17.0 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CEP13309.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 CEP13309.1 - 0.036 13.3 0.0 0.091 11.9 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Methyltransf_25 PF13649.6 CEP13310.1 - 1.8e-13 51.0 0.0 3.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP13310.1 - 2.7e-11 43.6 0.0 9.4e-11 41.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP13310.1 - 6.6e-10 39.5 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP13310.1 - 2.6e-07 30.5 0.0 8.5e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP13310.1 - 5.8e-07 29.1 0.1 1.6e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 CEP13310.1 - 7.3e-07 29.9 0.0 2.1e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP13310.1 - 1.2e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CEP13310.1 - 0.017 15.3 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.19 CEP13310.1 - 0.03 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CEP13310.1 - 0.071 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 CEP13310.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Gaa1 PF04114.14 CEP13311.1 - 9.6e-116 387.7 10.3 1.2e-115 387.4 10.3 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF4131 PF13567.6 CEP13311.1 - 0.32 10.6 5.9 0.44 10.2 0.5 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) GST_N_3 PF13417.6 CEP13312.1 - 1.3e-14 54.3 0.1 5.2e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP13312.1 - 9.2e-09 35.5 0.0 2.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP13312.1 - 7.4e-08 32.6 0.1 1.9e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP13312.1 - 1.9e-07 31.2 1.2 4.3e-07 30.1 0.3 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP13312.1 - 7.2e-05 22.9 1.6 0.0013 18.9 0.4 2.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP13312.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.6 CEP13312.1 - 0.078 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4105 PF13387.6 CEP13312.1 - 0.095 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Ribosomal_S7 PF00177.21 CEP13313.1 - 3.2e-37 127.5 0.8 3.9e-37 127.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e VRR_NUC PF08774.11 CEP13314.1 - 3.4e-21 75.3 0.0 7.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain DUF1938 PF09153.10 CEP13318.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) zf-C3HC PF07967.13 CEP13322.1 - 4.1e-18 65.7 6.7 1.3e-15 57.7 0.5 2.8 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 CEP13322.1 - 1.1e-14 54.4 1.4 3.9e-10 39.8 0.1 2.7 2 0 0 2 2 2 2 Rsm1-like zf-RVT PF13966.6 CEP13324.1 - 2.6e-08 34.5 2.1 3.3e-08 34.1 0.5 1.9 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase MSC PF09402.10 CEP13324.1 - 0.075 12.5 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DNA_pol_A_exo1 PF01612.20 CEP13325.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Cytochrome_P460 PF16694.5 CEP13325.1 - 0.17 12.2 4.0 0.33 11.3 4.0 1.5 1 0 0 1 1 1 0 Cytochrome P460 SUIM_assoc PF16619.5 CEP13325.1 - 0.68 10.0 7.0 0.61 10.2 5.0 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PIF1 PF05970.14 CEP13326.1 - 4.6e-13 49.1 0.0 5.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP13326.1 - 0.00098 18.9 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2009 PF09418.10 CEP13327.1 - 6.3e-194 645.3 0.0 8.5e-194 644.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CEP13327.1 - 9.6e-06 25.7 6.2 2.1e-05 24.6 6.2 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CEP13327.1 - 0.00059 20.0 3.5 0.0013 18.9 3.5 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain 4HB_MCP_1 PF12729.7 CEP13327.1 - 0.013 15.1 1.8 0.029 13.9 0.2 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction zf-C3HC4_3 PF13920.6 CEP13327.1 - 0.054 13.4 5.2 0.11 12.4 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CEP13328.1 - 4.8e-50 169.8 0.0 3.1e-49 167.1 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP13328.1 - 9.3e-30 103.2 0.0 3.2e-28 98.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEP13328.1 - 0.03 14.6 0.1 0.77 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CEP13328.1 - 0.22 11.8 2.5 0.61 10.4 0.3 2.5 2 1 1 3 3 3 0 AAA domain CMS1 PF14617.6 CEP13328.1 - 0.25 10.7 0.0 0.25 10.7 0.0 3.7 4 1 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit MCM_bind PF09739.9 CEP13328.1 - 2 6.8 9.5 2.6 6.4 9.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RNA_pol_Rpc4 PF05132.14 CEP13328.1 - 9.5 6.6 14.6 21 5.5 14.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF5308 PF17233.2 CEP13328.1 - 10 6.4 7.4 34 4.6 7.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Sec23_trunk PF04811.15 CEP13329.1 - 3.3e-74 249.5 0.0 5.1e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEP13329.1 - 1.4e-24 85.8 0.1 2.9e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEP13329.1 - 2e-16 60.5 0.0 4.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEP13329.1 - 3.3e-16 59.0 2.4 6.8e-16 58.0 2.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEP13329.1 - 8.6e-09 35.2 0.0 2.4e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CEP13329.1 - 0.007 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 CEP13329.1 - 0.0084 16.8 0.1 0.18 12.4 0.1 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CEP13329.1 - 0.083 13.1 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain 5-FTHF_cyc-lig PF01812.20 CEP13330.1 - 1.6e-26 93.3 0.4 3.5e-25 89.0 0.0 2.0 1 1 1 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family TraL PF07178.11 CEP13331.1 - 0.15 12.5 1.2 0.28 11.7 0.3 1.8 2 0 0 2 2 2 0 TraL protein Mucin PF01456.17 CEP13331.1 - 0.34 10.9 26.3 1.3 9.0 24.1 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein THF_DHG_CYH PF00763.23 CEP13332.1 - 4.7e-26 91.4 0.1 9.7e-26 90.3 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CEP13332.1 - 1.2e-15 57.2 0.1 3.6e-13 49.2 0.1 3.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_C PF02080.21 CEP13332.1 - 0.11 12.3 0.1 1.7 8.6 0.0 2.8 2 1 1 3 3 3 0 TrkA-C domain UDPG_MGDP_dh_N PF03721.14 CEP13332.1 - 0.11 12.0 0.2 1.1 8.9 0.2 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KH_8 PF17903.1 CEP13333.1 - 3.8e-06 26.9 0.0 8.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CEP13333.1 - 0.0027 17.5 0.3 0.0061 16.4 0.3 1.6 1 0 0 1 1 1 1 KH domain LSM PF01423.22 CEP13334.1 - 2.2e-18 65.7 0.1 2.8e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain Cytochrom_C1 PF02167.15 CEP13335.1 - 1.7e-98 328.7 0.0 2.3e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CEP13335.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CEP13335.1 - 0.042 15.0 0.2 0.14 13.3 0.2 2.1 1 1 0 1 1 1 0 Cytochrome c ANAPC1 PF12859.7 CEP13336.1 - 1.8e-10 41.4 0.0 5.6e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CEP13336.1 - 0.002 18.4 2.8 9.2 6.9 0.0 4.8 4 0 0 4 4 4 2 Proteasome/cyclosome repeat ATP-grasp_4 PF13535.6 CEP13336.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RNA_pol_N PF01194.17 CEP13337.1 - 2.9e-33 114.0 0.3 3.3e-33 113.8 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 CEP13338.1 - 1.1e-23 83.1 2.7 3.4e-07 30.8 0.2 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13338.1 - 7.8e-11 42.1 0.3 0.037 14.3 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP13338.1 - 0.0002 20.8 0.4 0.0084 15.5 0.7 2.4 2 1 0 2 2 2 1 WD40-like domain RIBIOP_C PF04950.12 CEP13339.1 - 2.1e-113 378.6 0.4 2.1e-113 378.6 0.4 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CEP13339.1 - 1.6e-24 85.8 0.0 4.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CDC45 PF02724.14 CEP13339.1 - 0.53 8.5 12.0 0.9 7.7 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Swi6_N PF18530.1 CEP13340.1 - 0.02 15.0 1.3 0.084 13.0 0.1 2.2 2 1 0 2 2 2 0 Swi6 N-terminal domain zf-C3H1 PF10650.9 CEP13342.1 - 1.4e-09 37.5 0.2 2.4e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain eIF-5a PF01287.20 CEP13342.1 - 0.047 13.8 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RXT2_N PF08595.11 CEP13343.1 - 5.8e-12 45.9 0.6 5.8e-12 45.9 0.6 2.9 2 2 0 2 2 2 1 RXT2-like, N-terminal NifQ PF04891.12 CEP13343.1 - 1.1 9.6 7.3 0.46 10.8 1.8 2.4 1 1 1 2 2 2 0 NifQ Crystallin PF00525.18 CEP13344.1 - 0.18 12.0 0.0 0.18 12.0 0.0 1.8 3 0 0 3 3 3 0 Alpha crystallin A chain, N terminal zf-C2H2 PF00096.26 CEP13345.1 - 3.9e-09 36.5 23.3 0.00014 22.1 1.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP13345.1 - 3.5e-08 33.6 21.6 0.0091 16.8 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP13345.1 - 9.1e-08 32.2 22.4 0.00021 21.6 4.3 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CEP13345.1 - 0.0028 17.4 20.7 0.073 12.8 0.3 4.8 4 0 0 4 4 4 3 C2H2-type zinc-finger domain PRA-CH PF01502.18 CEP13345.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase FOXP-CC PF16159.5 CEP13345.1 - 0.35 11.5 6.9 2 9.1 0.7 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 CEP13345.1 - 1.9 8.3 5.4 3.9 7.3 0.2 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type Arf PF00025.21 CEP13346.1 - 6.2e-64 214.7 0.0 6.8e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEP13346.1 - 7.2e-10 38.6 0.0 9.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEP13346.1 - 3e-09 36.5 0.1 7.1e-06 25.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CEP13346.1 - 3.3e-08 33.3 0.0 4.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP13346.1 - 5.7e-08 33.0 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEP13346.1 - 2.8e-07 30.6 0.0 5.1e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP13346.1 - 2.8e-06 26.8 0.0 3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CEP13346.1 - 0.038 13.7 0.0 0.12 12.2 0.0 1.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 CEP13346.1 - 0.086 12.0 0.0 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 CEP13346.1 - 0.18 11.4 0.0 7.9 6.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Actin PF00022.19 CEP13347.1 - 1.9e-48 165.1 0.0 6.3e-48 163.4 0.0 1.8 1 1 1 2 2 2 1 Actin MreB_Mbl PF06723.13 CEP13347.1 - 2.9e-14 52.6 0.0 6.1e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CEP13347.1 - 0.004 17.6 0.2 0.019 15.4 0.0 2.2 2 1 0 2 2 2 1 Cell division protein FtsA Exo_endo_phos PF03372.23 CEP13348.1 - 4.6e-11 42.7 0.0 7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 CEP13348.1 - 1.5e-08 34.6 0.1 5.6e-08 32.8 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.6 CEP13348.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like DSPc PF00782.20 CEP13349.1 - 2.6e-24 85.5 0.6 2.6e-24 85.5 0.6 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CEP13349.1 - 4.1e-10 40.1 0.1 1.3e-07 32.1 0.0 3.2 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 CEP13349.1 - 0.00031 20.4 0.1 0.0006 19.4 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 3H PF02829.14 CEP13349.1 - 0.0063 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 3H domain PTPlike_phytase PF14566.6 CEP13349.1 - 0.0069 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CEP13349.1 - 0.011 15.3 0.2 0.025 14.2 0.2 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Corona_nucleoca PF00937.18 CEP13349.1 - 0.017 14.2 0.0 0.054 12.5 0.0 1.8 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Init_tRNA_PT PF04179.12 CEP13349.1 - 0.025 14.9 0.0 0.084 13.2 0.0 1.9 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 CEP13349.1 - 0.037 14.0 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF4160 PF13711.6 CEP13349.1 - 0.1 12.9 0.4 3.5 8.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) DUF1176 PF06674.11 CEP13349.1 - 0.38 10.2 3.0 0.83 9.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) IF4E PF01652.18 CEP13350.1 - 5.6e-57 192.0 0.4 6.6e-57 191.8 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IL4Ra_N PF09238.10 CEP13351.1 - 0.0079 16.5 1.0 0.015 15.7 1.0 1.4 1 0 0 1 1 1 1 Interleukin-4 receptor alpha chain, N-terminal HTH_Tnp_1_2 PF13022.6 CEP13352.1 - 0.042 14.0 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TMEM247 PF15444.6 CEP13353.1 - 0.0025 17.9 1.8 0.16 12.0 1.8 2.0 1 1 0 1 1 1 1 Transmembrane protein 247 DUF4722 PF15849.5 CEP13353.1 - 0.054 13.2 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) Hat1_N PF10394.9 CEP13354.1 - 3.2e-49 167.2 1.0 6.1e-49 166.3 1.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CEP13354.1 - 5.2e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 CEP13354.1 - 0.00063 19.4 1.9 0.0014 18.3 0.8 1.8 1 1 1 2 2 2 1 MOZ/SAS family HCMV_UL139 PF12507.8 CEP13354.1 - 5.7 7.3 7.3 4.2 7.8 2.1 3.1 3 1 0 3 3 3 0 Human Cytomegalovirus UL139 protein Chitin_synth_2 PF03142.15 CEP13356.1 - 1.9e-233 775.9 3.1 3e-233 775.2 3.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP13356.1 - 4.8e-13 49.5 0.1 1.1e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP13356.1 - 4.4e-11 43.1 4.8 1.4e-10 41.5 4.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CEP13356.1 - 0.0011 18.4 0.1 0.0037 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CEP13356.1 - 0.019 14.7 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Orthoreo_P10 PF07204.11 CEP13356.1 - 0.17 11.9 0.8 0.62 10.0 0.8 2.0 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DDE_3 PF13358.6 CEP13357.1 - 1.4e-05 24.9 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box PF00505.19 CEP13358.1 - 2.3e-24 85.6 1.9 3.9e-24 84.8 1.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP13358.1 - 9.3e-18 64.6 2.2 9.3e-18 64.6 2.2 1.4 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 CEP13358.1 - 0.0021 18.0 0.0 0.0072 16.3 0.0 1.8 1 1 1 2 2 2 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 CEP13358.1 - 0.0058 16.6 1.9 0.0072 16.3 1.6 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box 5 Neugrin PF06413.11 CEP13359.1 - 5.4e-08 33.1 1.5 7.7e-08 32.6 0.5 1.6 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 CEP13359.1 - 6.4e-05 23.2 0.4 6.4e-05 23.2 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Mannosyl_trans3 PF11051.8 CEP13360.1 - 1e-36 126.7 0.3 1.8e-23 83.3 0.0 2.4 1 1 1 2 2 2 2 Mannosyltransferase putative NAD_binding_4 PF07993.12 CEP13360.1 - 1.6e-33 115.9 0.0 2.7e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CEP13360.1 - 1.1e-07 31.6 0.0 7.1e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Acyltransferase PF01553.21 CEP13360.1 - 4.4e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase GDP_Man_Dehyd PF16363.5 CEP13360.1 - 0.0028 17.1 0.2 0.056 12.8 0.2 2.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CEP13360.1 - 0.011 14.8 0.3 2 7.5 0.1 3.1 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein ZnuA PF01297.17 CEP13360.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic IL15 PF02372.15 CEP13360.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Interleukin 15 Sterile PF03015.19 CEP13360.1 - 0.73 10.1 8.0 0.3 11.4 0.7 3.6 3 0 0 3 3 3 0 Male sterility protein BPL_N PF09825.9 CEP13361.1 - 3.8e-109 365.2 0.0 4.7e-109 364.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CEP13361.1 - 1.5e-21 76.7 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CEP13361.1 - 8.4e-06 25.6 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.14 CEP13361.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain IBR PF01485.21 CEP13362.1 - 1.4e-17 63.6 51.0 4.3e-10 39.7 8.5 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DNA_pol_A_exo1 PF01612.20 CEP13362.1 - 2.9e-16 59.7 0.0 1.1e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease zf-RING_2 PF13639.6 CEP13362.1 - 4.9e-05 23.6 7.2 4.9e-05 23.6 7.2 4.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 CEP13362.1 - 0.00016 21.5 7.1 0.00016 21.5 7.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP13362.1 - 0.0012 18.9 6.6 0.0012 18.9 6.6 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEP13362.1 - 0.0069 16.2 7.5 0.0069 16.2 7.5 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) IFT20 PF14931.6 CEP13362.1 - 0.042 14.0 2.0 0.27 11.4 2.0 2.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 CHCH PF06747.13 CEP13363.1 - 8.8e-09 35.3 6.4 1.2e-08 34.8 6.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CEP13363.1 - 0.0055 16.7 1.6 0.0085 16.1 1.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CEP13363.1 - 0.0067 16.1 0.5 0.0085 15.8 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 CEP13363.1 - 0.0088 16.3 4.5 0.038 14.3 4.5 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Meis_PKNOX_N PF16493.5 CEP13363.1 - 0.038 14.3 3.0 2.3 8.6 0.3 2.2 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 COX17 PF05051.13 CEP13363.1 - 0.074 13.4 3.1 1.3 9.4 0.5 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 CEP13363.1 - 0.37 10.8 4.5 1.6 8.8 4.7 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, adh_short PF00106.25 CEP13364.1 - 1.6e-40 138.6 0.0 2.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP13364.1 - 9.3e-23 81.0 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP13364.1 - 9.1e-13 48.5 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CEP13364.1 - 0.00065 19.2 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CEP13364.1 - 0.0016 17.5 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CEP13364.1 - 0.0017 17.8 0.0 0.0032 17.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CEP13364.1 - 0.0032 16.8 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 CEP13364.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 CEP13364.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 CEP13364.1 - 0.057 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PGP_phosphatase PF09419.10 CEP13365.1 - 7.2e-47 159.1 0.0 8.8e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CEP13365.1 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF5644 PF18712.1 CEP13366.1 - 0.047 13.7 0.5 0.085 12.9 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Isochorismatase PF00857.20 CEP13368.1 - 0.082 13.1 0.2 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 Isochorismatase family TFIIA PF03153.13 CEP13368.1 - 0.21 11.6 9.3 0.021 14.8 4.9 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 CEP13368.1 - 0.39 9.8 11.0 0.082 12.0 6.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF1616 PF07760.11 CEP13368.1 - 2.2 7.6 7.0 4 6.7 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Med15_fungi PF05397.12 CEP13369.1 - 1.7e-32 112.0 0.3 1.7e-32 112.0 0.3 9.7 10 2 0 10 10 10 1 Mediator complex subunit 15 KIX_2 PF16987.5 CEP13369.1 - 2.8e-09 36.8 0.1 2.8e-09 36.8 0.1 5.0 4 0 0 4 4 4 1 KIX domain Mtc PF03820.17 CEP13370.1 - 5.5e-106 354.1 3.0 6.4e-106 353.9 3.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NiFe_hyd_3_EhaA PF17367.2 CEP13370.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A Aminotran_1_2 PF00155.21 CEP13371.1 - 4.8e-26 91.8 0.0 6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II IlvN PF07991.12 CEP13371.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain zinc_ribbon_9 PF14369.6 CEP13372.1 - 0.037 14.3 0.2 0.079 13.2 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon COG2 PF06148.11 CEP13373.1 - 0.2 11.7 0.2 0.2 11.7 0.2 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_L2_C PF03947.18 CEP13374.1 - 4.1e-46 156.3 3.6 4.1e-46 156.3 3.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEP13374.1 - 7.8e-16 57.8 0.1 2e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MAS20 PF02064.15 CEP13375.1 - 9.8e-38 129.2 1.1 9.8e-38 129.2 1.1 2.0 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 CEP13375.1 - 1.6e-05 25.3 2.2 3.8e-05 24.1 0.6 2.0 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 CEP13375.1 - 0.00023 21.2 8.3 0.00038 20.5 8.3 1.3 1 0 0 1 1 1 1 MYND finger DUF2691 PF10903.8 CEP13375.1 - 0.022 14.6 2.3 0.42 10.5 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2691) zf-FLZ PF04570.14 CEP13375.1 - 0.079 12.4 5.6 0.17 11.4 5.6 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 YajC PF02699.15 CEP13375.1 - 0.24 11.3 4.5 0.16 11.8 0.4 2.6 3 0 0 3 3 3 0 Preprotein translocase subunit MAD PF05557.13 CEP13376.1 - 3.7e-24 85.1 71.3 2.6e-17 62.5 0.4 3.0 1 1 2 3 3 3 2 Mitotic checkpoint protein Lebercilin PF15619.6 CEP13376.1 - 3.3e-05 23.6 9.2 3.3e-05 23.6 9.2 7.5 5 3 1 7 7 7 1 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 CEP13376.1 - 0.0013 18.9 8.3 0.0013 18.9 8.3 6.4 3 2 2 5 5 5 2 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 CEP13376.1 - 0.0094 16.0 1.9 0.0094 16.0 1.9 7.1 6 1 1 7 7 7 2 Designed helical repeat protein 10 domain Acetyltransf_1 PF00583.25 CEP13377.1 - 7.2e-14 52.0 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP13377.1 - 3.1e-09 37.1 0.0 4.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP13377.1 - 7.8e-07 29.1 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GATA PF00320.27 CEP13378.1 - 4.8e-17 61.3 3.3 1.2e-16 60.0 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CEP13378.1 - 5.1e-14 51.8 0.9 1.3e-13 50.5 0.9 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PSCyt3 PF07627.11 CEP13378.1 - 2.6 8.4 6.6 3.1 8.1 3.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) DDE_Tnp_1_7 PF13843.6 CEP13379.1 - 2.8e-06 26.9 0.0 3.5e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 RhoGAP PF00620.27 CEP13381.1 - 1e-26 93.6 0.0 3.3e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 CEP13381.1 - 7.5e-25 87.5 0.7 4.7e-24 85.0 0.1 2.4 2 0 0 2 2 2 1 MyTH4 domain Pkinase PF00069.25 CEP13382.1 - 1.3e-68 231.2 0.0 1.7e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13382.1 - 2.2e-32 112.4 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13382.1 - 1.8e-08 34.1 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CEP13382.1 - 0.0043 16.7 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CEP13382.1 - 0.017 14.1 0.1 0.086 11.8 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP13382.1 - 0.033 13.0 0.1 0.059 12.1 0.1 1.6 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 CEP13382.1 - 0.05 14.3 0.6 0.11 13.2 0.6 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain E1-E2_ATPase PF00122.20 CEP13383.1 - 6.6e-48 162.6 5.9 6.6e-48 162.6 5.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP13383.1 - 4.8e-35 120.9 7.6 4.8e-35 120.9 7.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEP13383.1 - 3.9e-25 89.4 1.6 9.2e-24 84.9 0.4 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP13383.1 - 4.7e-19 68.3 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEP13383.1 - 5e-16 58.1 0.0 1.6e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP13383.1 - 1.2e-07 31.7 0.7 2.6e-05 24.1 0.3 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP13383.1 - 0.0082 16.6 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4056 PF13265.6 CEP13383.1 - 0.018 14.4 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4056) PAS_3 PF08447.12 CEP13384.1 - 1.2e-15 57.6 0.0 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CEP13384.1 - 3.8e-07 30.3 0.2 0.036 14.3 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CEP13384.1 - 1.1e-06 28.6 0.0 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CEP13384.1 - 1.2e-05 25.4 0.0 0.00081 19.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain Glyco_trans_1_2 PF13524.6 CEP13384.1 - 0.024 15.0 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 NRD1_2 PF01995.16 CEP13384.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 SpoU_methylase PF00588.19 CEP13385.1 - 1.3e-25 90.2 0.0 1.3e-24 87.0 0.0 2.7 3 0 0 3 3 3 1 SpoU rRNA Methylase family XPG_I PF00867.18 CEP13386.1 - 5.3e-20 71.6 0.0 1.2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEP13386.1 - 1.9e-10 41.1 0.0 6.5e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEP13386.1 - 0.02 14.4 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 XPG domain containing zf-C2H2 PF00096.26 CEP13387.1 - 1.3e-21 75.7 59.3 5e-05 23.5 3.4 8.5 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP13387.1 - 4.4e-13 48.9 55.2 0.013 16.3 1.2 8.8 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP13387.1 - 5e-12 45.5 23.9 0.0023 17.9 1.2 5.8 5 0 0 5 5 5 5 C2H2-type zinc finger zf-met PF12874.7 CEP13387.1 - 4.4e-06 26.9 32.3 0.0092 16.3 0.3 6.6 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP13387.1 - 4.7e-06 26.7 30.8 0.0018 18.5 0.3 6.9 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CEP13387.1 - 7e-05 23.1 58.6 0.0062 16.9 0.4 9.2 9 1 0 9 9 7 4 Zinc-finger double domain GAGA PF09237.11 CEP13387.1 - 0.00094 18.9 6.9 0.0025 17.6 2.0 3.3 2 1 1 3 3 3 1 GAGA factor FOXP-CC PF16159.5 CEP13387.1 - 0.0016 19.0 29.1 0.003 18.1 0.3 7.2 3 2 4 7 7 7 1 FOXP coiled-coil domain zf-Di19 PF05605.12 CEP13387.1 - 0.015 15.5 3.8 0.015 15.5 3.8 5.9 3 1 4 7 7 6 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CEP13387.1 - 0.022 14.9 1.1 0.022 14.9 1.1 4.1 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 CEP13387.1 - 0.064 13.4 0.1 0.064 13.4 0.1 4.7 2 1 0 2 2 1 0 Aberrant zinc-finger ORF6N PF10543.9 CEP13387.1 - 0.071 13.3 0.1 0.46 10.7 0.1 2.3 2 0 0 2 2 2 0 ORF6N domain zf-C2H2_9 PF16293.5 CEP13387.1 - 0.077 12.9 8.9 4.3 7.3 0.3 4.4 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Arc_trans_TRASH PF08394.10 CEP13387.1 - 0.085 13.2 4.5 0.85 10.0 0.5 3.7 2 1 0 2 2 2 0 Archaeal TRASH domain zf_UBZ PF18439.1 CEP13387.1 - 0.089 12.4 9.4 3.3 7.4 0.1 4.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 CEP13387.1 - 0.17 12.2 28.6 0.12 12.7 8.2 4.1 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CEP13387.1 - 0.39 11.1 32.8 1.5 9.2 0.5 6.2 1 1 2 5 5 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CEP13387.1 - 0.55 10.9 17.2 2 9.1 0.5 4.8 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats FYDLN_acid PF09538.10 CEP13387.1 - 0.59 10.8 3.9 0.54 11.0 1.4 2.2 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) zf-HYPF PF07503.12 CEP13387.1 - 1.1 9.1 6.3 33 4.4 1.8 3.7 3 0 0 3 3 3 0 HypF finger zf-Dof PF02701.15 CEP13387.1 - 1.3 9.3 9.0 0.12 12.5 1.8 2.9 3 0 0 3 3 2 0 Dof domain, zinc finger DZR PF12773.7 CEP13387.1 - 1.7 8.8 11.5 2e+02 2.1 11.5 3.4 1 1 0 1 1 1 0 Double zinc ribbon PyrI_C PF02748.15 CEP13387.1 - 2.6 8.0 12.5 1.6 8.7 0.3 4.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RVT_1 PF00078.27 CEP13389.1 - 8.1e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Jnk-SapK_ap_N PF09744.9 CEP13390.1 - 0.13 12.5 7.7 0.28 11.4 7.7 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cas9_PI PF16595.5 CEP13390.1 - 0.39 10.6 6.4 0.15 11.9 1.6 2.0 2 0 0 2 2 2 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 Peptidase_S21 PF00716.17 CEP13390.1 - 3.9 7.1 11.3 8.3 6.0 11.3 1.6 1 1 0 1 1 1 0 Assemblin (Peptidase family S21) MMR_HSR1 PF01926.23 CEP13391.1 - 6.4e-08 32.7 0.0 1.9e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP13391.1 - 1.7e-05 24.4 0.0 0.0013 18.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP13391.1 - 3.5e-05 23.8 0.0 0.0015 18.5 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 CEP13391.1 - 0.0093 16.2 0.0 0.046 13.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CEP13391.1 - 0.01 15.3 0.0 0.89 9.1 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B TniB PF05621.11 CEP13391.1 - 0.017 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein TRAF6_Z2 PF18048.1 CEP13391.1 - 0.022 14.8 0.3 0.09 12.9 0.3 2.0 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Ras PF00071.22 CEP13391.1 - 0.029 14.0 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 CEP13391.1 - 0.047 12.8 0.0 3.4 6.7 0.0 2.4 3 0 0 3 3 3 0 G-protein alpha subunit AIG1 PF04548.16 CEP13391.1 - 0.2 10.9 0.8 4.2 6.6 0.2 2.3 1 1 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 CEP13391.1 - 0.84 9.7 3.8 4.4 7.3 1.2 2.9 2 1 0 2 2 2 0 Dynamin family DUF747 PF05346.11 CEP13392.1 - 4.6e-109 364.7 14.2 6.7e-109 364.2 14.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family MIT PF04212.18 CEP13393.1 - 0.0029 17.6 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1308 PF07000.11 CEP13394.1 - 7.5e-21 74.8 0.0 5.5e-19 68.7 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 CEP13394.1 - 1.6e-18 66.9 1.0 1.8e-13 50.3 0.1 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5614) F_bP_aldolase PF01116.20 CEP13395.1 - 1.1e-91 307.2 0.0 1.5e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.17 CEP13395.1 - 0.2 11.1 0.6 2 7.8 0.1 2.1 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain LSM PF01423.22 CEP13396.1 - 3.4e-19 68.3 0.1 3.8e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CEP13396.1 - 0.00049 20.2 0.0 0.00056 20.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CEP13396.1 - 0.003 17.6 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain FYDLN_acid PF09538.10 CEP13397.1 - 0.053 14.2 4.9 0.11 13.2 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFIIF_alpha PF05793.12 CEP13397.1 - 0.37 9.3 12.2 0.52 8.8 12.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.9 CEP13397.1 - 0.51 9.4 12.2 0.68 9.0 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CEP13397.1 - 0.54 8.4 5.2 0.54 8.4 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CEP13397.1 - 0.7 8.1 4.9 0.76 8.0 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CEP13397.1 - 1.9 8.1 5.2 6.5 6.4 5.2 1.9 1 1 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CEP13397.1 - 8.2 4.4 10.2 10 4.1 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nas2_N PF18265.1 CEP13398.1 - 2.6e-29 100.9 1.5 4.1e-29 100.3 1.0 1.6 1 1 1 2 2 2 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CEP13398.1 - 5.2e-08 32.6 0.1 8.9e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 CEP13398.1 - 4.8e-07 30.2 0.0 1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CEP13398.1 - 1.2e-06 28.7 0.0 2.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CEP13398.1 - 0.00018 21.8 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Pox_A6 PF04924.12 CEP13398.1 - 0.0043 16.1 0.2 0.0073 15.3 0.2 1.3 1 0 0 1 1 1 1 Poxvirus A6 protein DegS PF05384.11 CEP13398.1 - 0.0063 16.0 0.7 0.59 9.6 0.0 2.2 2 0 0 2 2 2 1 Sensor protein DegS HALZ PF02183.18 CEP13398.1 - 0.014 15.6 0.9 0.033 14.4 0.9 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prefoldin_2 PF01920.20 CEP13398.1 - 0.044 13.7 1.0 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit Enkurin PF13864.6 CEP13398.1 - 0.096 13.1 1.3 0.22 12.0 0.2 1.9 2 0 0 2 2 2 0 Calmodulin-binding NYD-SP28_assoc PF14775.6 CEP13398.1 - 0.39 10.9 3.0 1.4 9.1 0.3 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain RPT PF13446.6 CEP13399.1 - 0.028 14.3 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF2406 PF10295.9 CEP13399.1 - 0.055 14.2 0.1 0.073 13.8 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein (DUF2406) CENP-F_leu_zip PF10473.9 CEP13400.1 - 0.0012 18.8 4.7 0.002 18.2 4.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4971 PF16341.5 CEP13400.1 - 0.038 13.8 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4971) OrfB_Zn_ribbon PF07282.11 CEP13400.1 - 0.045 13.7 4.0 0.48 10.4 4.0 2.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Laminin_II PF06009.12 CEP13400.1 - 0.067 13.2 2.5 0.15 12.1 2.5 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF641 PF04859.12 CEP13400.1 - 1.1 9.7 5.7 0.67 10.3 1.4 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) zf-C2H2_jaz PF12171.8 CEP13401.1 - 0.00047 20.4 1.2 0.0012 19.1 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP13401.1 - 0.0025 18.1 0.3 0.0045 17.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.8 CEP13401.1 - 0.016 15.1 6.1 0.016 15.1 6.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.7 CEP13401.1 - 0.049 14.0 1.7 0.049 14.0 1.7 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_18 PF13238.6 CEP13401.1 - 1.2 9.7 16.3 0.051 14.1 8.2 2.3 1 1 1 2 2 2 0 AAA domain Cu-oxidase_2 PF07731.14 CEP13402.1 - 6.7e-42 142.5 8.7 6.3e-39 132.8 0.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEP13402.1 - 9.9e-36 122.4 6.8 4.1e-33 113.9 0.4 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CEP13402.1 - 2.6e-31 108.9 3.8 5.6e-31 107.8 0.3 2.7 3 0 0 3 3 3 1 Multicopper oxidase Peptidase_M30 PF10460.9 CEP13402.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M30 UQ_con PF00179.26 CEP13403.1 - 6.3e-45 152.3 0.0 7e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 CEP13403.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 CEP13403.1 - 0.018 15.3 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CEP13403.1 - 0.04 13.6 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B CTP_transf_like PF01467.26 CEP13404.1 - 1.5e-11 44.7 0.1 5.8e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like DPBB_1 PF03330.18 CEP13404.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Cons_hypoth95 PF03602.15 CEP13404.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Sulfotransfer_1 PF00685.27 CEP13405.1 - 3.3e-09 36.6 0.1 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEP13405.1 - 7.1e-09 36.4 0.2 0.00095 19.6 0.1 3.5 3 1 0 3 3 3 2 Sulfotransferase family Cyt_bd_oxida_I PF01654.17 CEP13406.1 - 0.046 12.3 0.3 0.055 12.1 0.3 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I FAD_binding_7 PF03441.14 CEP13406.1 - 0.05 13.1 0.0 0.069 12.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase COX7B PF05392.11 CEP13406.1 - 0.16 11.7 0.0 8.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB p450 PF00067.22 CEP13407.1 - 4.9e-70 236.6 0.1 6.5e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CP2 PF04516.15 CEP13408.1 - 2.7e-47 161.0 11.5 6.6e-47 159.7 7.2 2.8 2 1 0 2 2 2 1 CP2 transcription factor nos_propeller_2 PF18793.1 CEP13408.1 - 0.029 14.7 0.1 0.076 13.4 0.1 1.6 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 DUF4508 PF14969.6 CEP13408.1 - 0.18 12.1 0.8 27 5.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) Amidohydro_1 PF01979.20 CEP13409.1 - 3.1e-70 237.2 2.1 4.7e-70 236.6 2.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 CEP13409.1 - 8.5e-55 184.3 1.3 1.6e-54 183.4 1.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Abhydrolase_3 PF07859.13 CEP13409.1 - 9.7e-43 146.5 0.1 2.3e-42 145.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Urease_beta PF00699.20 CEP13409.1 - 7.8e-42 141.3 0.0 1.5e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 CEP13409.1 - 1.3e-34 118.5 0.0 3.8e-34 117.0 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Say1_Mug180 PF10340.9 CEP13409.1 - 3.9e-16 58.9 0.1 8.8e-16 57.7 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase Amidohydro_3 PF07969.11 CEP13409.1 - 6.9e-06 25.8 0.3 0.00029 20.4 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family COesterase PF00135.28 CEP13409.1 - 0.0035 16.3 0.1 0.0085 15.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Isochorismatase PF00857.20 CEP13410.1 - 5e-10 39.8 0.0 7.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF1780 PF08682.10 CEP13410.1 - 0.089 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) MLVIN_C PF18697.1 CEP13411.1 - 0.00084 19.4 0.0 0.0028 17.7 0.0 2.0 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3275 PF11679.8 CEP13411.1 - 0.34 10.9 3.2 0.48 10.4 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) RVT_1 PF00078.27 CEP13412.1 - 1.4e-08 34.5 0.0 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH_3 PF13392.6 CEP13413.1 - 0.25 11.1 0.6 11 5.9 0.1 2.8 3 1 1 4 4 4 0 HNH endonuclease Nrap_D5 PF17406.2 CEP13415.1 - 0.0012 18.6 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 adh_short PF00106.25 CEP13417.1 - 1.7e-42 145.1 0.7 2e-42 144.8 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP13417.1 - 2.7e-30 105.6 0.1 3.6e-30 105.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP13417.1 - 3.2e-06 27.2 0.1 4.7e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP13417.1 - 9.6e-05 21.9 0.2 0.00046 19.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEP13417.1 - 0.00087 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CEP13417.1 - 0.0034 17.6 0.2 0.03 14.6 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 CEP13417.1 - 0.048 13.2 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 CEP13417.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 CEP13418.1 - 2.8e-55 187.5 0.5 5.6e-55 186.5 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13418.1 - 5.8e-40 137.2 0.3 9.1e-40 136.6 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CEP13418.1 - 5.6e-05 23.3 0.2 0.00014 22.1 0.2 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain MerR_2 PF13591.6 CEP13418.1 - 0.0075 16.1 1.3 0.017 15.0 0.2 2.2 2 0 0 2 2 2 1 MerR HTH family regulatory protein APH PF01636.23 CEP13418.1 - 0.012 15.5 0.1 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family GH114_assoc PF14741.6 CEP13418.1 - 0.026 14.7 0.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain DUF4373 PF14297.6 CEP13418.1 - 0.11 13.3 1.2 15 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) ADIP PF11559.8 CEP13418.1 - 1.1 9.4 13.2 0.16 12.0 8.4 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RNB PF00773.19 CEP13420.1 - 7.4e-95 318.0 0.0 7.4e-95 318.0 0.0 2.4 3 0 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 CEP13420.1 - 1.4e-22 79.5 0.0 3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEP13420.1 - 4.9e-14 52.4 0.0 4.9e-14 52.4 0.0 3.4 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 CEP13420.1 - 1.3e-07 31.4 0.0 1.3e-07 31.4 0.0 3.0 3 0 0 3 3 3 1 Rrp44-like cold shock domain CSD2 PF17876.1 CEP13420.1 - 8.7e-07 29.0 0.0 0.012 15.8 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 CEP13420.1 - 0.0022 17.6 0.0 0.0067 16.1 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Rrp44_S1 PF17215.3 CEP13420.1 - 0.056 13.4 1.0 0.59 10.1 0.0 2.8 3 0 0 3 3 3 0 S1 domain Glyco_trans_2_3 PF13632.6 CEP13421.1 - 7.2e-14 52.2 1.0 7.2e-14 52.2 1.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF4375 PF14300.6 CEP13421.1 - 0.11 12.8 0.1 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) RIO1 PF01163.22 CEP13422.1 - 1.4e-74 249.8 2.2 1.4e-74 249.8 2.2 1.6 2 0 0 2 2 2 1 RIO1 family CDC45 PF02724.14 CEP13422.1 - 0.0014 17.0 10.8 0.0014 17.0 10.8 1.7 2 0 0 2 2 2 1 CDC45-like protein APH PF01636.23 CEP13422.1 - 0.0066 16.4 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEP13422.1 - 0.02 14.2 0.3 0.16 11.3 0.3 2.1 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.6 CEP13422.1 - 0.03 15.0 0.0 0.069 13.8 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain YL1 PF05764.13 CEP13422.1 - 1.2 9.2 33.1 0.04 14.0 20.4 2.5 2 0 0 2 2 2 0 YL1 nuclear protein HSP90 PF00183.18 CEP13423.1 - 5.4e-172 573.3 8.0 8.6e-172 572.6 8.0 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CEP13423.1 - 2.9e-11 43.9 0.0 7.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP13423.1 - 4.4e-11 42.8 0.0 1.9e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M50B PF13398.6 CEP13424.1 - 1e-55 188.5 18.0 1.4e-55 188.0 18.0 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Ndc1_Nup PF09531.10 CEP13424.1 - 2.5 6.7 9.3 3.8 6.1 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSase_L_D3 PF02787.19 CEP13426.1 - 0.13 12.6 0.5 0.17 12.2 0.5 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RVT_1 PF00078.27 CEP13428.1 - 1.1e-18 67.6 0.7 1.6e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) BBP1_C PF15272.6 CEP13428.1 - 0.091 12.6 1.8 0.14 12.0 1.8 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF4767 PF15983.5 CEP13428.1 - 0.11 12.8 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) Asp_protease_2 PF13650.6 CEP13430.1 - 0.00064 20.3 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP13430.1 - 0.007 16.9 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CEP13430.1 - 0.064 13.4 2.1 0.14 12.3 2.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Fer2_4 PF13510.6 CEP13431.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Nup_retrotrp_bd PF10599.9 CEP13438.1 - 0.23 12.2 6.8 0.25 12.0 6.4 1.4 1 1 0 1 1 1 0 Retro-transposon transporting motif YL1 PF05764.13 CEP13440.1 - 0.0037 17.4 5.0 0.0037 17.4 5.0 1.9 2 0 0 2 2 2 1 YL1 nuclear protein Transferase PF02458.15 CEP13441.1 - 1.1e-26 93.5 0.0 5.4e-26 91.2 0.0 1.8 1 1 0 1 1 1 1 Transferase family Rrp15p PF07890.12 CEP13442.1 - 8.3e-34 116.8 8.0 8.3e-34 116.8 8.0 2.4 2 1 0 2 2 2 1 Rrp15p BSP_II PF05432.11 CEP13442.1 - 0.0074 16.0 18.5 0.011 15.5 18.5 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Pes-10 PF07149.11 CEP13442.1 - 0.49 9.4 15.3 0.89 8.5 15.3 1.5 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 CEP13442.1 - 1.3 7.5 11.8 1.4 7.4 11.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 KCT2 PF17818.1 CEP13442.1 - 2.5 8.2 11.3 5.1 7.2 11.3 1.5 1 0 0 1 1 1 0 Keratinocyte-associated gene product TPT PF03151.16 CEP13443.1 - 6.3e-29 101.2 24.9 8e-29 100.9 24.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEP13443.1 - 3.2e-08 33.8 41.1 4.7e-07 30.0 14.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family GWT1 PF06423.12 CEP13443.1 - 0.0051 17.0 1.8 0.0051 17.0 1.8 2.4 2 1 0 3 3 3 1 GWT1 LcrR PF09621.10 CEP13443.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) DUF4834 PF16118.5 CEP13443.1 - 4.9 8.2 0.0 4.9 8.2 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) G-patch PF01585.23 CEP13444.1 - 1e-15 57.3 1.4 1.9e-15 56.5 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP13444.1 - 8.3e-08 32.2 0.3 3.4e-07 30.3 0.3 2.1 1 0 0 1 1 1 1 G-patch domain zf-C2H2_11 PF16622.5 CEP13444.1 - 0.0018 18.0 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CEP13444.1 - 0.0058 16.9 0.6 0.011 16.0 0.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CEP13444.1 - 0.021 15.3 0.2 0.05 14.1 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Trypan_PARP PF05887.11 CEP13444.1 - 0.027 14.5 2.3 0.027 14.5 2.3 2.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) zf-met PF12874.7 CEP13444.1 - 0.087 13.2 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP13444.1 - 0.11 13.4 0.1 0.28 12.1 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP13444.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DDE_3 PF13358.6 CEP13445.1 - 3.1e-19 69.2 0.0 2.8e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP13445.1 - 0.00038 20.2 0.0 0.00092 18.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP13445.1 - 0.0039 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP13445.1 - 0.031 14.6 0.0 0.31 11.4 0.0 2.5 3 0 0 3 3 3 0 Transposase HTH_28 PF13518.6 CEP13445.1 - 0.036 14.2 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 CEP13445.1 - 0.047 13.7 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_17 PF12728.7 CEP13445.1 - 0.058 13.6 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 CEP13445.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HSP70 PF00012.20 CEP13446.1 - 1.3e-08 33.5 0.0 8.9e-08 30.8 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP13446.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 CEP13447.1 - 1.2e-61 208.4 0.0 2.4e-61 207.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13447.1 - 2.8e-35 121.9 0.0 5.1e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEP13447.1 - 7.9e-17 60.8 0.0 1.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 CEP13447.1 - 4.4e-05 22.9 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP13447.1 - 5.8e-05 22.5 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP13447.1 - 0.00011 22.2 0.0 0.078 12.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP13447.1 - 0.00063 18.8 0.1 0.0014 17.6 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CEP13447.1 - 0.04 13.5 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PCI PF01399.27 CEP13448.1 - 3.4e-06 27.5 0.4 1.9e-05 25.1 0.1 2.4 2 0 0 2 2 2 1 PCI domain CENP-T_C PF15511.6 CEP13449.1 - 9.8e-09 35.3 0.1 1.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CEP13449.1 - 4.1e-05 23.7 0.1 5.8e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CEP13449.1 - 5.7e-05 23.5 0.1 6.8e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP13449.1 - 9.5e-05 22.7 0.1 0.00013 22.3 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEP13449.1 - 0.00023 21.4 0.1 0.00048 20.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP13449.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP13449.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CEP13449.1 - 0.16 12.5 0.1 0.31 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CEP13450.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP13450.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEP13450.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEP13450.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEP13450.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP13450.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP13450.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Fungal_trans PF04082.18 CEP13451.1 - 1.3e-14 53.9 4.7 1.3e-14 53.9 4.7 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP13451.1 - 1.4e-09 37.9 12.4 2.3e-09 37.2 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mak10 PF04112.13 CEP13451.1 - 0.0062 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3602 PF12223.8 CEP13452.1 - 0.0095 16.5 0.6 0.019 15.6 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) SARS_3b PF12383.8 CEP13452.1 - 0.014 15.5 0.5 0.017 15.2 0.5 1.1 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein Prominin PF05478.11 CEP13452.1 - 0.071 11.1 0.3 0.074 11.0 0.3 1.0 1 0 0 1 1 1 0 Prominin DHBP_synthase PF00926.19 CEP13455.1 - 8.8e-84 279.8 0.1 9.9e-84 279.6 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Flavokinase PF01687.17 CEP13456.1 - 6.4e-37 126.3 0.0 7.9e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase LigT_PEase PF02834.16 CEP13457.1 - 0.028 14.6 0.1 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 LigT like Phosphoesterase DUF2854 PF11016.8 CEP13457.1 - 0.14 12.1 1.0 0.43 10.5 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2854) RPA_interact_M PF14767.6 CEP13458.1 - 0.021 15.4 2.2 0.021 15.4 2.2 3.3 2 1 0 2 2 2 0 Replication protein A interacting middle ATP-synt_ab_N PF02874.23 CEP13459.1 - 4.6e-24 84.7 1.7 8.6e-24 83.8 1.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 CEP13459.1 - 0.009 15.7 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain CSD2 PF17876.1 CEP13459.1 - 0.12 12.6 1.7 0.42 10.8 0.4 2.5 3 0 0 3 3 3 0 Cold shock domain DEAD_2 PF06733.15 CEP13460.1 - 1.3e-54 184.5 0.1 2.2e-54 183.8 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 CEP13460.1 - 4.2e-47 160.3 1.6 5.2e-43 146.9 0.4 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CEP13460.1 - 4.3e-43 147.5 0.0 8.4e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2075 PF09848.9 CEP13460.1 - 0.049 12.9 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CEP13460.1 - 0.085 12.9 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CEP13460.1 - 0.097 12.1 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 CEP13460.1 - 0.11 11.2 0.0 1.2 7.8 0.0 2.3 2 1 0 2 2 2 0 SNF2 family N-terminal domain Inositol_P PF00459.25 CEP13461.1 - 1.7e-58 198.3 1.4 2.7e-58 197.6 1.4 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family ADH_N PF08240.12 CEP13462.1 - 1.1e-28 99.2 2.1 1.8e-28 98.6 2.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP13462.1 - 1.4e-26 93.0 0.0 2.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CEP13462.1 - 7.4e-11 41.9 0.7 1.3e-09 37.8 0.7 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CEP13462.1 - 0.029 15.4 0.0 0.051 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Isochorismatase PF00857.20 CEP13464.1 - 5.2e-09 36.5 0.1 7.7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family DDE_3 PF13358.6 CEP13465.1 - 9.2e-07 28.7 0.0 4e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_1 PF00126.27 CEP13465.1 - 0.045 13.7 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_50 PF18024.1 CEP13465.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 CEP13465.1 - 0.071 13.7 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain SNARE_assoc PF09335.11 CEP13466.1 - 1.8e-19 70.4 3.7 2e-18 67.0 4.6 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein CSN8_PSD8_EIF3K PF10075.9 CEP13467.1 - 1.8e-30 105.8 0.6 1.8e-30 105.8 0.6 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CEP13467.1 - 5.3e-06 26.0 0.3 6.9e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family Cornichon PF03311.14 CEP13468.1 - 1.5e-49 167.4 10.8 1.7e-49 167.2 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein O-FucT PF10250.9 CEP13469.1 - 2.3e-11 44.0 1.1 3.6e-10 40.1 1.1 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Casc1 PF12366.8 CEP13469.1 - 0.013 15.0 0.4 0.022 14.3 0.4 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Pirin_C_2 PF17954.1 CEP13469.1 - 0.039 14.1 0.3 0.086 13.0 0.3 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain CBS PF00571.28 CEP13470.1 - 4.6e-13 49.4 0.8 0.00014 22.3 0.0 3.7 4 0 0 4 4 4 3 CBS domain ALS_ss_C PF10369.9 CEP13471.1 - 1.1e-17 64.0 0.4 9.2e-16 57.8 0.0 2.7 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 CEP13471.1 - 8.5e-14 51.0 0.2 1.7e-13 50.0 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CEP13471.1 - 5.9e-09 35.6 0.1 1.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 CEP13471.1 - 0.083 13.5 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 ACT domain LytR_C PF13399.6 CEP13471.1 - 0.13 13.3 0.0 0.45 11.5 0.0 1.9 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator ResIII PF04851.15 CEP13472.1 - 7.6e-29 100.9 0.1 7.6e-29 100.9 0.1 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP13472.1 - 5.9e-14 52.3 0.7 2.6e-13 50.3 0.1 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CEP13472.1 - 1.1e-12 48.1 1.4 8.5e-12 45.2 0.0 2.4 2 1 1 3 3 3 1 SWI2/SNF2 ATPase DEAD PF00270.29 CEP13472.1 - 4.9e-10 39.5 0.6 1.2e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CEP13472.1 - 0.0014 18.0 0.9 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 CEP13472.1 - 0.0087 15.3 0.8 0.018 14.3 0.8 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T2SSE PF00437.20 CEP13472.1 - 0.026 13.6 0.3 0.049 12.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 CEP13472.1 - 0.077 13.3 0.7 0.65 10.3 0.0 2.6 2 2 1 3 3 3 0 AAA domain GST_N_2 PF13409.6 CEP13473.1 - 0.0027 18.0 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP13473.1 - 0.0048 17.2 0.0 0.0057 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP13474.1 - 3.7e-18 65.5 0.0 8.8e-18 64.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP13474.1 - 5e-05 23.4 0.0 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP13475.1 - 3.8e-17 62.3 0.9 6e-17 61.7 0.9 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP13475.1 - 1.5e-05 25.2 0.2 3.2e-05 24.1 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CEP13475.1 - 0.0031 18.2 0.0 0.013 16.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 CEP13475.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEP13475.1 - 0.033 14.6 0.0 0.058 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP13475.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LIM PF00412.22 CEP13476.1 - 1.6e-14 53.8 18.0 1.3e-11 44.6 8.6 2.2 2 0 0 2 2 2 2 LIM domain Churchill PF06573.11 CEP13476.1 - 0.057 13.8 0.3 0.057 13.8 0.3 2.1 2 0 0 2 2 2 0 Churchill protein CsbD PF05532.12 CEP13477.1 - 2.3e-14 53.0 19.5 1.6e-10 40.7 6.1 2.1 1 1 1 2 2 2 2 CsbD-like Mito_carr PF00153.27 CEP13478.1 - 1.7e-63 210.6 9.7 5e-21 74.4 0.1 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein FUSC_2 PF13515.6 CEP13478.1 - 2.4e-17 63.2 12.4 2.4e-17 63.2 12.4 2.9 2 1 0 2 2 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEP13478.1 - 1.1e-13 50.6 0.1 1.1e-13 50.6 0.1 2.7 2 1 1 3 3 3 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 CEP13478.1 - 4.1e-13 49.2 10.6 2.1e-10 40.3 0.1 2.4 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CEP13478.1 - 7.6e-11 42.3 6.5 2.3e-10 40.7 2.6 2.9 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CEP13478.1 - 1.1e-10 41.0 2.5 1.1e-10 41.0 2.5 3.2 2 1 0 2 2 2 1 Aluminium activated malate transporter EF-hand_7 PF13499.6 CEP13478.1 - 1.7e-08 34.8 0.7 4.3e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP13478.1 - 0.00042 20.0 1.3 7.4 6.8 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CEP13478.1 - 0.0083 16.0 1.1 0.081 12.8 0.0 3.1 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP13478.1 - 0.033 13.7 0.5 4 7.2 0.0 3.6 4 0 0 4 4 4 0 EF hand Focal_AT PF03623.13 CEP13478.1 - 0.18 11.8 0.9 0.5 10.4 0.9 1.8 1 0 0 1 1 1 0 Focal adhesion targeting region DUF2222 PF09984.9 CEP13478.1 - 1.8 8.4 4.4 2.3 8.1 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) ArAE_1 PF06081.11 CEP13478.1 - 4.3 7.5 12.9 0.45 10.6 7.5 2.3 2 0 0 2 2 1 0 Aromatic acid exporter family member 1 Vps5 PF09325.10 CEP13479.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like FAM110_C PF14160.6 CEP13479.1 - 0.12 13.4 0.8 0.39 11.8 0.1 1.9 2 0 0 2 2 2 0 Centrosome-associated C terminus rve PF00665.26 CEP13480.1 - 2.1e-16 60.2 0.0 5.3e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CEP13480.1 - 0.001 18.8 0.0 0.0034 17.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13480.1 - 0.022 14.8 0.2 0.054 13.6 0.2 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain RT_RNaseH PF17917.1 CEP13481.1 - 1.8e-18 66.7 0.0 2.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13481.1 - 9.5e-06 25.6 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PSP PF04046.16 CEP13481.1 - 0.1 12.5 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 PSP RVT_1 PF00078.27 CEP13482.1 - 2.1e-12 47.0 0.0 1.2e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP13482.1 - 5.3e-05 23.1 7.0 0.0001 22.2 7.0 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.11 CEP13482.1 - 0.0022 17.8 0.4 0.054 13.3 0.2 2.8 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CEP13482.1 - 0.028 15.0 0.2 1.6 9.4 0.0 3.0 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 CEP13482.1 - 1.6 8.5 9.6 2.9 7.7 9.6 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ETC_C1_NDUFA4 PF04800.12 CEP13484.1 - 4.7e-36 122.9 0.8 6.3e-36 122.5 0.8 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Lon_C PF05362.13 CEP13485.1 - 8.8e-71 237.7 0.0 1.6e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CEP13485.1 - 1.2e-24 87.2 0.0 3.1e-24 85.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CEP13485.1 - 1.8e-18 67.2 0.5 9.5e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 CEP13485.1 - 5.3e-08 32.8 0.0 1.5e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CEP13485.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CEP13485.1 - 1.7e-05 24.0 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.14 CEP13485.1 - 1.8e-05 24.9 0.0 6.1e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEP13485.1 - 7.2e-05 23.1 0.3 0.0098 16.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 CEP13485.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEP13485.1 - 0.00015 21.8 0.0 0.0045 17.0 0.0 3.1 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CEP13485.1 - 0.00027 20.7 0.0 0.001 18.9 0.0 1.8 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CEP13485.1 - 0.00045 20.6 0.9 0.0024 18.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 CEP13485.1 - 0.0011 18.7 0.1 0.0035 17.1 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CEP13485.1 - 0.0032 18.0 0.2 0.0091 16.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 CEP13485.1 - 0.0043 17.0 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase NB-ARC PF00931.22 CEP13485.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CEP13485.1 - 0.025 15.0 0.0 0.087 13.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 CEP13485.1 - 0.031 13.5 0.0 0.73 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 CEP13485.1 - 0.048 13.6 0.3 0.47 10.4 0.0 2.7 3 0 0 3 3 3 0 NACHT domain SKI PF01202.22 CEP13485.1 - 0.081 13.0 0.5 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase ClpB_D2-small PF10431.9 CEP13485.1 - 0.1 12.7 0.4 0.54 10.4 0.0 2.4 2 0 0 2 2 1 0 C-terminal, D2-small domain, of ClpB protein TsaE PF02367.17 CEP13485.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CEP13485.1 - 0.32 11.5 2.1 1.5 9.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Ran-binding PF05508.11 CEP13486.1 - 3.2e-35 121.6 3.2 4.5e-33 114.6 3.2 2.9 1 1 0 1 1 1 1 RanGTP-binding protein Alpha-amylase_C PF02806.18 CEP13487.1 - 1.5e-28 99.1 0.1 3.7e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CEP13487.1 - 4.5e-17 62.2 0.1 1.3e-16 60.7 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CEP13487.1 - 1.2e-13 51.4 0.0 1.7e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF2417 PF10329.9 CEP13489.1 - 4.2 6.7 21.8 0.076 12.4 11.6 2.7 2 1 1 3 3 3 0 Region of unknown function (DUF2417) FAR1 PF03101.15 CEP13490.1 - 8.1e-07 29.7 3.6 1.4e-06 28.9 3.6 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain ABC2_membrane_3 PF12698.7 CEP13490.1 - 0.18 10.9 1.5 0.22 10.6 1.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein O-antigen_lig PF13425.6 CEP13490.1 - 2.2 7.0 5.3 3.3 6.4 5.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein MULE PF10551.9 CEP13491.1 - 5.6e-12 45.9 0.2 5.6e-07 29.9 0.0 2.8 1 1 1 2 2 2 2 MULE transposase domain FAR1 PF03101.15 CEP13491.1 - 1.2e-05 25.8 2.9 3.1e-05 24.6 2.9 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4110 PF13422.6 CEP13491.1 - 0.00024 21.1 1.0 0.92 9.6 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4110) PCI PF01399.27 CEP13491.1 - 0.0062 17.0 3.4 2.7 8.6 0.1 3.6 2 1 1 3 3 3 2 PCI domain GlcNAc-1_reg PF18440.1 CEP13491.1 - 0.017 15.3 0.2 14 6.0 0.0 3.1 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF2877 PF11392.8 CEP13491.1 - 0.023 15.4 1.9 8.9 7.1 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2877) DUF4998 PF16389.5 CEP13491.1 - 0.032 13.8 0.5 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF1661 PF07877.11 CEP13491.1 - 2.3 8.0 5.5 88 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1661) DUF4159 PF13709.6 CEP13492.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) L_HMGIC_fpl PF10242.9 CEP13493.1 - 0.64 10.2 4.9 0.26 11.5 1.8 1.6 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein F-box-like PF12937.7 CEP13494.1 - 1.9e-09 37.3 0.0 4.9e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP13494.1 - 4e-07 29.7 0.2 1.2e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain DAGAT PF03982.13 CEP13495.1 - 2.3e-101 338.6 0.0 2.8e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_3 PF07859.13 CEP13496.1 - 2.9e-25 89.4 0.0 8.8e-25 87.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CEP13496.1 - 3.7e-21 75.6 0.1 1.3e-20 73.8 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family FSH1 PF03959.13 CEP13496.1 - 0.0074 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 CEP13496.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ASH PF15780.5 CEP13497.1 - 1.6e-11 44.3 12.2 0.3 11.3 0.0 10.8 12 0 0 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CEP13497.1 - 3.1e-07 30.5 0.6 0.22 11.7 0.0 6.2 6 0 0 6 6 6 1 Flagellar-associated PapD-like DUF1573 PF07610.11 CEP13497.1 - 0.0003 20.8 0.3 29 4.8 0.0 6.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1573) Transglut_C PF00927.22 CEP13497.1 - 0.0045 17.1 0.1 0.34 11.1 0.0 3.8 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain SUIM_assoc PF16619.5 CEP13497.1 - 0.042 13.9 4.5 0.23 11.5 4.5 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BsuPI PF12690.7 CEP13497.1 - 0.049 13.7 0.3 20 5.3 0.0 3.6 3 0 0 3 3 3 0 Intracellular proteinase inhibitor DUF1120 PF06551.12 CEP13497.1 - 4 7.6 16.1 0.26 11.5 0.8 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1120) zf-CCHC PF00098.23 CEP13498.1 - 0.014 15.5 0.1 0.014 15.5 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 CEP13498.1 - 0.035 14.1 1.3 0.035 14.1 1.3 2.2 1 1 1 2 2 2 0 Zinc knuckle Pol_alpha_B_N PF08418.10 CEP13498.1 - 0.051 13.5 5.3 0.081 12.9 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TRAF6_Z2 PF18048.1 CEP13498.1 - 3.6 7.8 7.9 23 5.2 2.3 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 PUD1_2 PF18457.1 CEP13500.1 - 0.0093 16.0 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 DUF4515 PF14988.6 CEP13500.1 - 0.041 13.7 2.4 0.053 13.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Ins_allergen_rp PF06757.13 CEP13500.1 - 0.049 13.6 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification PIF1 PF05970.14 CEP13504.1 - 6e-14 52.0 0.2 7.6e-14 51.7 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP13504.1 - 2.8e-05 22.3 0.0 3.2e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP13504.1 - 0.024 14.5 0.1 0.073 12.9 0.1 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AdoMet_MTase PF07757.13 CEP13505.1 - 8.2e-39 132.4 0.0 1.5e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 CEP13505.1 - 0.00018 21.6 1.2 0.0012 18.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP13505.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP13505.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CEP13505.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP13505.1 - 0.0099 16.6 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP13505.1 - 0.028 15.1 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 CEP13505.1 - 0.051 13.2 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 CEP13505.1 - 0.081 13.7 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Podoplanin PF05808.11 CEP13506.1 - 0.0047 17.1 7.1 0.0047 17.1 7.1 2.3 1 1 1 2 2 2 1 Podoplanin MtrF PF09472.10 CEP13506.1 - 0.22 10.9 0.5 0.52 9.7 0.5 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) F-box-like PF12937.7 CEP13507.1 - 7.8e-06 25.7 0.0 2.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP13507.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain eIF-5_eIF-2B PF01873.17 CEP13508.1 - 5.1e-42 142.4 0.6 2.5e-40 137.0 0.2 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 W2 PF02020.18 CEP13508.1 - 1.8e-18 66.5 0.8 1.8e-18 66.5 0.8 2.4 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Sel1 PF08238.12 CEP13509.1 - 9.9e-101 327.9 102.7 9.1e-09 35.7 0.2 28.1 28 0 0 28 28 28 22 Sel1 repeat ANTAR PF03861.14 CEP13509.1 - 0.018 14.9 0.3 2.8 7.8 0.0 3.4 2 0 0 2 2 2 0 ANTAR domain TPR_6 PF13174.6 CEP13509.1 - 0.038 14.6 34.2 19 6.2 0.1 13.7 14 1 1 15 15 15 0 Tetratricopeptide repeat TPR_3 PF07720.12 CEP13509.1 - 0.06 13.3 2.9 0.51 10.4 2.9 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP13509.1 - 0.81 10.4 0.0 0.81 10.4 0.0 11.5 13 1 1 14 14 14 0 Tetratricopeptide repeat TPR_20 PF14561.6 CEP13509.1 - 1.5 9.2 7.5 10 6.5 1.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP13509.1 - 2 8.7 25.7 0.78 10.0 2.3 7.4 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 PadR PF03551.14 CEP13510.1 - 0.13 12.3 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RRM_1 PF00076.22 CEP13511.1 - 2.8e-12 46.3 0.3 1e-11 44.5 0.2 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP13511.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0669 PF17065.5 CEP13511.1 - 0.056 13.2 0.2 0.075 12.8 0.2 1.2 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 3Beta_HSD PF01073.19 CEP13512.1 - 5.8e-69 232.2 0.0 7.4e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CEP13512.1 - 3.6e-35 121.6 0.0 4.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CEP13512.1 - 8.9e-20 71.3 0.0 1.6e-18 67.2 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CEP13512.1 - 6.1e-15 55.1 0.0 7.6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CEP13512.1 - 1.9e-11 43.7 0.0 3e-10 39.7 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CEP13512.1 - 6.6e-10 39.2 0.0 8.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CEP13512.1 - 9e-08 31.6 0.0 5.3e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CEP13512.1 - 0.00097 19.1 0.1 0.056 13.3 0.1 2.4 1 1 0 1 1 1 1 KR domain RNA_pol_A_bac PF01000.26 CEP13513.1 - 9.5e-33 112.9 0.0 1.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEP13513.1 - 1.7e-21 75.4 0.0 2.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Scramblase PF03803.15 CEP13514.1 - 0.052 12.8 0.2 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Scramblase DCP1 PF06058.13 CEP13515.1 - 2.7e-35 120.8 0.1 4.7e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 CEP13515.1 - 0.0037 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus MAT1 PF06391.13 CEP13515.1 - 0.015 15.2 8.3 0.025 14.4 8.3 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ndc1_Nup PF09531.10 CEP13515.1 - 0.29 9.8 9.8 0.32 9.6 9.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BRF1 PF07741.13 CEP13515.1 - 0.92 9.9 5.9 0.27 11.6 2.8 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SMYLE_N PF18615.1 CEP13515.1 - 1.2 8.6 7.6 1.7 8.1 7.6 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Lin-8 PF03353.15 CEP13515.1 - 2.6 7.5 14.1 3.8 7.0 14.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Calpain_inhib PF00748.19 CEP13515.1 - 8.1 7.0 11.5 19 5.8 11.5 1.6 1 0 0 1 1 1 0 Calpain inhibitor bZIP_1 PF00170.21 CEP13516.1 - 1.7e-07 31.2 5.9 1.7e-07 31.2 5.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor SH3_9 PF14604.6 CEP13516.1 - 1.4e-06 28.0 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain bZIP_2 PF07716.15 CEP13516.1 - 7.3e-05 22.8 4.7 7.3e-05 22.8 4.7 2.0 2 0 0 2 2 2 1 Basic region leucine zipper SH3_1 PF00018.28 CEP13516.1 - 0.0039 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP13516.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain CYYR1 PF10873.8 CEP13516.1 - 0.27 11.6 7.0 0.052 14.0 3.0 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Adeno_E3_CR2 PF02439.15 CEP13516.1 - 1.2 9.0 6.7 0.076 12.8 1.0 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Vac7 PF12751.7 CEP13518.1 - 1.1e-09 38.2 1.1 1.1e-09 38.2 1.1 2.8 1 1 1 2 2 2 2 Vacuolar segregation subunit 7 PH PF00169.29 CEP13519.1 - 8.6e-14 51.9 2.6 9.2e-14 51.8 0.4 2.1 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 CEP13519.1 - 5.2e-05 23.6 3.7 0.00059 20.2 3.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEP13519.1 - 0.00045 20.4 0.5 0.68 10.3 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CEP13519.1 - 0.0024 18.2 1.3 0.0071 16.7 1.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain G-gamma PF00631.22 CEP13520.1 - 2.7e-17 62.5 0.0 2.9e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain GntR PF00392.21 CEP13520.1 - 0.13 11.9 0.2 0.24 11.1 0.2 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_32 PF13565.6 CEP13521.1 - 0.012 16.2 0.0 0.077 13.6 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CEP13521.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_1 PF00126.27 CEP13521.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Senescence_reg PF04520.13 CEP13521.1 - 0.16 12.8 1.6 0.2 12.5 1.2 1.4 1 1 0 1 1 1 0 Senescence regulator HTH_32 PF13565.6 CEP13523.1 - 0.012 16.2 0.0 0.077 13.6 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CEP13523.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_1 PF00126.27 CEP13523.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Senescence_reg PF04520.13 CEP13523.1 - 0.13 13.0 1.5 0.17 12.7 1.2 1.4 1 1 0 1 1 1 0 Senescence regulator Serinc PF03348.15 CEP13524.1 - 4e-149 497.2 6.6 4.6e-149 497.0 6.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM43 PF07787.12 CEP13524.1 - 0.23 10.8 1.9 0.64 9.4 1.9 1.9 1 0 0 1 1 1 0 Transmembrane protein 43 DUF2070 PF09843.9 CEP13524.1 - 2.7 6.2 8.1 4.8 5.4 8.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF218 PF02698.17 CEP13525.1 - 0.00081 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain LON_substr_bdg PF02190.16 CEP13526.1 - 5e-14 52.7 0.0 1.1e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 CEP13526.1 - 7.6e-10 38.8 27.7 5.1e-06 26.5 10.3 3.2 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CEP13526.1 - 1.2e-08 34.8 23.6 0.00013 21.9 7.2 2.9 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_10 PF16685.5 CEP13526.1 - 2e-06 27.8 22.6 3.6e-05 23.8 4.6 2.8 3 0 0 3 3 3 2 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 CEP13526.1 - 3.8e-06 26.7 20.0 0.0049 16.7 6.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP13526.1 - 2.1e-05 24.3 22.3 0.018 14.9 9.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP13526.1 - 0.00019 21.2 25.1 0.0045 16.8 8.9 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP13526.1 - 0.00038 20.3 26.9 0.031 14.2 8.3 2.8 2 1 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 CEP13526.1 - 0.013 15.4 23.3 0.15 11.9 8.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CEP13526.1 - 0.059 13.7 23.7 0.31 11.4 8.0 2.7 2 0 0 2 2 2 0 Ring finger domain zf-Nse PF11789.8 CEP13526.1 - 3.2 7.7 14.1 0.27 11.1 4.1 3.4 3 1 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 CEP13526.1 - 9.1 6.2 13.0 12 5.8 3.7 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MULE PF10551.9 CEP13527.1 - 2.5e-10 40.6 0.7 9.6e-10 38.8 0.7 2.1 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 CEP13527.1 - 6.9e-05 22.4 0.3 0.00014 21.4 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 CEP13527.1 - 0.0026 17.5 0.2 0.0087 15.8 0.1 2.0 2 0 0 2 2 2 1 Transposase Transposase_mut PF00872.18 CEP13527.1 - 0.0043 15.9 0.3 0.0073 15.2 0.3 1.4 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.15 CEP13527.1 - 0.012 16.3 0.5 0.028 15.1 0.5 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.6 CEP13527.1 - 0.015 15.6 1.1 1.5 9.0 0.1 3.2 2 1 1 3 3 3 0 DDE domain Tiam_CC_Ex PF18385.1 CEP13527.1 - 0.072 13.5 0.4 0.97 9.9 0.1 2.5 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain DUF3603 PF12227.8 CEP13527.1 - 0.1 11.9 1.6 0.43 9.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3603) Pkinase PF00069.25 CEP13529.1 - 4.6e-37 127.8 0.0 8.8e-11 41.7 0.0 4.4 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13529.1 - 5.2e-18 65.3 0.0 3.8e-05 23.1 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.14 CEP13529.1 - 0.03 13.7 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BicD PF09730.9 CEP13529.1 - 0.082 11.3 6.5 0.13 10.6 6.5 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Lipoprotein_6 PF01441.19 CEP13529.1 - 0.084 12.9 1.3 0.18 11.8 1.3 1.5 1 0 0 1 1 1 0 Lipoprotein Remorin_C PF03763.13 CEP13529.1 - 0.33 10.9 5.6 0.82 9.6 5.6 1.7 1 0 0 1 1 1 0 Remorin, C-terminal region UPF0242 PF06785.11 CEP13529.1 - 0.71 9.9 10.2 1.2 9.2 10.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 CEP13529.1 - 1.2 9.6 6.4 0.29 11.6 2.0 2.1 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 CEP13529.1 - 1.9 8.8 11.2 4.6 7.6 11.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Kelch_5 PF13854.6 CEP13530.1 - 9.6e-18 63.8 0.2 0.00041 20.3 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CEP13530.1 - 1.2e-17 63.1 0.5 1.9e-05 24.4 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CEP13530.1 - 6.8e-17 61.1 0.4 0.00018 21.7 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CEP13530.1 - 1.5e-13 50.6 14.3 8.1e-07 29.2 0.0 6.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CEP13530.1 - 2.4e-13 49.9 0.3 0.00024 21.1 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP13530.1 - 1.2e-12 47.2 0.8 0.013 15.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 CEP13530.1 - 1.9e-09 37.7 6.4 0.00041 20.6 0.4 3.4 3 0 0 3 3 3 2 BTB/POZ domain DWNN PF08783.11 CEP13530.1 - 0.029 14.6 0.7 6.3 7.2 0.0 3.0 2 0 0 2 2 2 0 DWNN domain Peptidase_S49_N PF08496.10 CEP13530.1 - 0.39 10.8 15.7 0.32 11.0 6.3 2.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Aa_trans PF01490.18 CEP13531.1 - 1.9e-61 208.0 33.4 2.2e-61 207.8 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CEP13531.1 - 1.2e-05 24.4 43.9 1.5e-05 24.0 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 CEP13531.1 - 0.0014 17.5 17.9 0.0014 17.5 17.9 2.7 2 2 0 2 2 2 1 Spore germination protein UPF0139 PF03669.13 CEP13531.1 - 0.84 9.5 3.4 0.84 9.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Aa_trans PF01490.18 CEP13532.1 - 1.4e-46 159.0 23.2 1.6e-46 158.9 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 CEP13532.1 - 4.8e-06 25.6 7.8 4.8e-06 25.6 7.8 2.8 2 2 0 3 3 3 1 Spore germination protein 7TMR-DISM_7TM PF07695.11 CEP13532.1 - 4.6 7.1 27.2 0.017 15.0 8.5 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling Aa_trans PF01490.18 CEP13533.1 - 1.3e-58 198.6 32.8 1.5e-58 198.4 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0139 PF03669.13 CEP13533.1 - 0.77 9.7 0.0 0.77 9.7 0.0 2.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0139) Helitron_like_N PF14214.6 CEP13534.1 - 2.4e-12 47.5 0.3 4.2e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PrgU PF09627.10 CEP13537.1 - 0.2 11.6 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 PrgU-like protein UvrD_C_2 PF13538.6 CEP13538.1 - 3.5e-08 33.2 0.0 9.1e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP13538.1 - 3.3e-05 22.1 0.0 7.2e-05 20.9 0.0 1.5 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 CEP13538.1 - 0.017 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Exo_endo_phos PF03372.23 CEP13540.1 - 0.02 14.4 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PH_RBD PF12068.8 CEP13542.1 - 0.019 14.4 0.2 0.035 13.6 0.2 1.4 1 0 0 1 1 1 0 Rab-binding domain (RBD) MAF_flag10 PF01973.18 CEP13542.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 DUF5041 PF16444.5 CEP13543.1 - 0.038 14.3 0.2 0.096 12.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5041) PIF1 PF05970.14 CEP13544.1 - 3.3e-06 26.5 0.1 3.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP13544.1 - 0.00029 20.6 0.0 0.00052 19.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP13544.1 - 0.00041 19.7 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 CEP13544.1 - 0.00062 20.2 0.1 0.0011 19.3 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP13544.1 - 0.0021 18.3 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CEP13544.1 - 0.0028 17.3 1.6 0.026 14.3 0.6 2.1 1 1 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CEP13544.1 - 0.004 16.9 0.1 0.035 13.8 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 CEP13544.1 - 0.0072 16.7 0.0 0.0097 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEP13544.1 - 0.015 15.3 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CEP13544.1 - 0.017 14.6 0.1 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF463 PF04317.12 CEP13544.1 - 0.02 13.8 0.2 0.02 13.8 0.2 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Viral_helicase1 PF01443.18 CEP13544.1 - 0.03 14.1 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CEP13544.1 - 0.035 13.3 0.2 0.057 12.6 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CEP13544.1 - 0.04 13.3 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CEP13544.1 - 0.044 13.6 0.0 0.046 13.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 CEP13544.1 - 0.044 11.7 0.0 0.044 11.7 0.0 1.2 1 0 0 1 1 1 0 Helicase MeaB PF03308.16 CEP13544.1 - 0.052 12.5 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 CEP13544.1 - 0.073 12.3 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 CEP13544.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.7 CEP13544.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.12 CEP13544.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_23 PF13476.6 CEP13544.1 - 0.11 13.0 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CEP13544.1 - 0.12 12.8 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CEP13544.1 - 0.31 10.1 3.3 0.11 11.6 0.6 1.6 1 1 1 2 2 2 0 Type II/IV secretion system protein HEPN_AbiU2 PF18734.1 CEP13545.1 - 0.00069 19.2 1.7 0.52 9.8 0.1 2.7 2 0 0 2 2 2 2 AbiU2 Tautomerase PF01361.21 CEP13545.1 - 0.053 13.4 0.0 4 7.4 0.0 2.8 2 0 0 2 2 2 0 Tautomerase enzyme Glyco_hydro_16 PF00722.21 CEP13546.1 - 3.5e-35 121.1 1.0 1.2e-34 119.3 0.3 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DEAD PF00270.29 CEP13546.1 - 5.6e-16 58.8 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase QCR10 PF09796.9 CEP13546.1 - 1.5e-12 47.3 1.4 2.2e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-H2C2_2 PF13465.6 CEP13546.1 - 0.062 13.8 0.4 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DHHC PF01529.20 CEP13547.1 - 0.0021 18.2 0.9 0.0021 18.2 0.9 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Presenilin PF01080.17 CEP13547.1 - 9.9 4.8 7.8 12 4.5 7.8 1.1 1 0 0 1 1 1 0 Presenilin Helicase_C PF00271.31 CEP13548.1 - 1.5e-30 105.8 0.0 2.6e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP13548.1 - 2.2e-24 86.2 0.0 4.8e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UTP25 PF06862.12 CEP13548.1 - 0.043 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helitron_like_N PF14214.6 CEP13549.1 - 1.8e-06 28.3 0.7 2.8e-06 27.7 0.7 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Corona_6B_7B PF03262.13 CEP13551.1 - 0.013 15.0 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Coronavirus 6B/7B protein RVT_1 PF00078.27 CEP13555.1 - 2.2e-11 43.7 0.0 2.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF656 PF04920.12 CEP13557.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) GIT_SHD PF08518.11 CEP13557.1 - 0.3 10.7 2.6 0.22 11.2 0.6 1.9 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT PIF1 PF05970.14 CEP13558.1 - 3.7e-11 42.8 0.1 5.1e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP13558.1 - 2.2e-08 34.0 0.0 4.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEP13558.1 - 6.4e-08 33.1 0.1 3e-07 30.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP13558.1 - 8.7e-06 26.1 0.1 7.7e-05 23.0 0.0 2.1 1 1 0 2 2 2 1 AAA domain TniB PF05621.11 CEP13558.1 - 0.00024 20.6 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein RNA_helicase PF00910.22 CEP13558.1 - 0.0019 18.5 0.0 0.0062 16.9 0.0 1.8 1 1 1 2 2 2 1 RNA helicase AAA_24 PF13479.6 CEP13558.1 - 0.0025 17.5 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEP13558.1 - 0.0074 15.7 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA PF00004.29 CEP13558.1 - 0.012 16.1 0.2 0.032 14.7 0.1 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEP13558.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 CEP13558.1 - 0.018 14.3 0.1 0.024 13.9 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CEP13558.1 - 0.024 14.0 0.2 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CEP13558.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 CEP13558.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 CEP13558.1 - 0.031 14.2 0.1 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 CEP13558.1 - 0.048 14.2 0.0 0.53 10.8 0.0 2.4 3 0 0 3 3 3 0 ABC transporter DNA_III_psi PF03603.13 CEP13558.1 - 0.052 13.8 0.1 0.077 13.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III psi subunit ATPase_2 PF01637.18 CEP13558.1 - 0.058 13.3 0.2 0.54 10.1 0.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CEP13558.1 - 0.12 12.1 0.1 0.38 10.5 0.0 1.8 2 1 0 2 2 1 0 AAA domain UvrD-helicase PF00580.21 CEP13558.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 CEP13558.1 - 0.16 11.8 0.9 0.52 10.2 0.9 2.0 1 1 0 1 1 1 0 NACHT domain KDZ PF18758.1 CEP13559.1 - 1.6e-06 27.9 0.4 1.9e-06 27.7 0.4 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase ADH_zinc_N PF00107.26 CEP13559.1 - 0.051 13.6 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DBD_Tnp_Mut PF03108.15 CEP13559.1 - 0.092 12.7 0.5 0.16 12.0 0.2 1.7 1 1 0 1 1 1 0 MuDR family transposase Peptidase_M16_C PF05193.21 CEP13560.1 - 0.77 9.8 3.7 1.2 9.1 3.7 1.3 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF4551 PF15087.6 CEP13560.1 - 3.5 6.4 13.4 3.5 6.4 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 CEP13560.1 - 5 7.0 27.7 6 6.8 27.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 CEP13560.1 - 5 6.8 9.3 5.7 6.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PRKG1_interact PF15898.5 CEP13560.1 - 6 7.8 7.6 2.4 9.1 0.3 1.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 CEP13560.1 - 8.6 6.8 8.7 6 7.3 6.8 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Neur_chan_memb PF02932.16 CEP13560.1 - 9.9 6.1 7.6 11 6.0 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-CCHC PF00098.23 CEP13562.1 - 0.0031 17.5 12.5 0.03 14.4 1.3 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP13562.1 - 0.032 14.0 4.1 0.032 14.0 4.1 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP13562.1 - 2 8.3 19.7 2.3 8.1 7.3 2.6 3 0 0 3 3 3 0 Zinc knuckle DDE_3 PF13358.6 CEP13563.1 - 8.6e-20 71.0 0.0 8e-18 64.6 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease ALS2CR8 PF15299.6 CEP13564.1 - 0.036 13.9 1.7 0.051 13.5 1.1 1.5 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DinI PF06183.13 CEP13564.1 - 0.15 12.4 0.1 0.68 10.3 0.0 2.0 1 1 1 2 2 2 0 DinI-like family DUF3294 PF07957.11 CEP13567.1 - 0.0054 16.5 0.5 0.0058 16.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF4298 PF14131.6 CEP13567.1 - 0.074 13.0 0.8 0.34 10.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Med10 PF09748.9 CEP13568.1 - 0.08 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex RVT_1 PF00078.27 CEP13570.1 - 1.6e-09 37.7 0.0 7.3e-09 35.5 0.0 2.1 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Podoplanin PF05808.11 CEP13572.1 - 0.0011 19.1 11.9 0.0021 18.2 11.9 1.5 1 0 0 1 1 1 1 Podoplanin SPX PF03105.19 CEP13572.1 - 0.63 9.9 5.5 0.65 9.9 5.5 1.2 1 0 0 1 1 1 0 SPX domain DUF4551 PF15087.6 CEP13572.1 - 1.5 7.6 4.1 1.9 7.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HTH_Tnp_Tc3_2 PF01498.18 CEP13574.1 - 1.8e-10 40.9 0.2 4.9e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CEP13574.1 - 0.0058 17.2 0.2 0.21 12.2 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP13574.1 - 0.021 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CEP13574.1 - 0.069 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 CEP13574.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_1_7 PF13843.6 CEP13575.1 - 0.00074 18.9 0.0 0.00077 18.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CEP13575.1 - 0.0071 16.0 0.0 0.0081 15.8 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF5552 PF17706.1 CEP13575.1 - 0.15 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5552) Pet127 PF08634.10 CEP13576.1 - 0.0091 15.5 1.5 0.012 15.1 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial protein Pet127 DDE_Tnp_1_7 PF13843.6 CEP13578.1 - 1.3e-26 93.8 0.0 1.8e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.27 CEP13579.1 - 7.5e-17 61.6 0.0 9.3e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 CEP13580.1 - 1.1e-06 28.8 0.1 5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Cnl2_NKP2 PF09447.10 CEP13580.1 - 0.042 14.0 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Cnl2/NKP2 family protein gag-asp_proteas PF13975.6 CEP13581.1 - 1.2e-05 25.8 0.1 2.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP13581.1 - 9e-05 23.1 0.1 0.00016 22.2 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CEP13581.1 - 0.00066 19.5 0.0 0.0016 18.2 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP13581.1 - 0.0065 16.2 0.2 0.014 15.1 0.2 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 CEP13581.1 - 0.091 12.5 0.2 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 CEP13582.1 - 3.9e-33 113.5 0.0 5.8e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP13582.1 - 6.5e-32 109.9 0.0 1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF374 PF04028.13 CEP13582.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) rve PF00665.26 CEP13583.1 - 1.7e-16 60.5 0.0 4.7e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13583.1 - 5.9e-09 35.9 0.9 5.9e-09 35.9 0.9 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CEP13583.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 CEP13583.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-H2C2 PF09337.10 CEP13583.1 - 0.36 11.1 3.4 0.2 11.9 0.9 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Cnn_1N PF07989.11 CEP13584.1 - 0.018 15.2 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Histidinol_dh PF00815.20 CEP13584.1 - 0.046 12.7 0.5 0.069 12.1 0.1 1.5 2 0 0 2 2 2 0 Histidinol dehydrogenase DUF4936 PF16290.5 CEP13584.1 - 0.059 14.1 0.1 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) NmrA PF05368.13 CEP13584.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DNA_pol_A_exo1 PF01612.20 CEP13585.1 - 0.0004 20.1 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 3'-5' exonuclease tRNA-synt_2c PF01411.19 CEP13586.1 - 2.5e-213 709.6 0.0 4.1e-213 708.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CEP13586.1 - 1.8e-18 66.4 0.1 4.4e-18 65.1 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CEP13586.1 - 6.6e-18 65.5 1.6 6.6e-18 65.5 1.6 2.5 4 0 0 4 4 4 1 DHHA1 domain Myb_DNA-bind_4 PF13837.6 CEP13586.1 - 4.5 7.7 5.0 1.2 9.5 1.0 2.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ead_Ea22 PF13935.6 CEP13586.1 - 9 7.0 8.8 1.9 9.2 1.9 2.9 3 0 0 3 3 3 0 Ead/Ea22-like protein ECR1_N PF14382.6 CEP13587.1 - 1.5e-14 53.5 1.1 4e-14 52.1 1.1 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CEP13587.1 - 7.5e-12 45.4 0.1 2.6e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 KH domain EXOSC1 PF10447.9 CEP13587.1 - 0.036 14.7 0.2 3.2 8.4 0.1 2.5 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 GRAM PF02893.20 CEP13588.1 - 1.1e-30 105.8 9.4 7.2e-21 74.2 1.9 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 CEP13588.1 - 6.7e-28 97.5 0.0 1.9e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 CEP13588.1 - 1.8e-12 47.7 2.4 7.1e-12 45.8 0.3 2.8 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 CEP13588.1 - 7.5e-08 31.6 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 CEP13588.1 - 1.5e-06 28.4 1.8 2.3e-06 27.8 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Na_H_Exchanger PF00999.21 CEP13589.1 - 6.2e-29 101.0 12.1 7.5e-29 100.7 12.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 CEP13589.1 - 0.072 13.2 1.0 0.072 13.2 1.0 2.6 3 0 0 3 3 3 0 YrhC-like protein Abhydrolase_9_N PF15420.6 CEP13589.1 - 0.17 11.9 4.0 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus 60KD_IMP PF02096.20 CEP13589.1 - 0.55 10.1 3.9 0.31 10.9 1.8 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein DUF2754 PF10953.8 CEP13589.1 - 8.1 6.8 9.3 3 8.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2754) WW PF00397.26 CEP13590.1 - 6.9e-05 22.9 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 WW domain FAD_binding_1 PF00667.20 CEP13593.1 - 1.3e-54 185.1 0.0 2.2e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP13593.1 - 1.9e-31 109.2 0.2 3.9e-31 108.2 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CEP13593.1 - 1.2e-17 64.5 0.0 7.2e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CEP13593.1 - 0.032 14.5 0.0 0.085 13.1 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Noc2 PF03715.13 CEP13594.1 - 0.06 12.6 0.0 0.081 12.2 0.0 1.1 1 0 0 1 1 1 0 Noc2p family Nramp PF01566.18 CEP13595.1 - 3.3e-108 361.9 16.2 3.3e-108 361.9 16.2 2.0 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein RhoGEF PF00621.20 CEP13596.1 - 1.6e-23 83.9 0.6 1.6e-23 83.9 0.6 1.7 2 0 0 2 2 2 1 RhoGEF domain CNH PF00780.22 CEP13596.1 - 2.1e-08 34.1 0.3 4.7e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 CEP13596.1 - 0.0014 18.7 1.1 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain DUF5390 PF17365.2 CEP13596.1 - 0.88 9.8 3.2 2.9 8.2 0.4 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5390) RVT_1 PF00078.27 CEP13597.1 - 3.7e-29 101.8 0.0 7.9e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP13597.1 - 1.9e-12 47.1 1.4 1.3e-11 44.3 0.6 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP13597.1 - 0.036 13.6 0.1 0.085 12.4 0.1 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Zein PF01559.16 CEP13597.1 - 0.33 10.5 4.2 9.3 5.8 0.1 3.1 3 0 0 3 3 3 0 Zein seed storage protein Phage_int_SAM_1 PF02899.17 CEP13598.1 - 0.0093 16.3 1.8 0.025 14.9 1.8 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP13598.1 - 0.048 14.1 1.1 0.11 12.9 0.9 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ANAPC2 PF08672.11 CEP13598.1 - 0.084 13.4 0.3 4.5 7.8 0.0 3.0 2 1 1 3 3 3 0 Anaphase promoting complex (APC) subunit 2 Phage_int_SAM_3 PF14659.6 CEP13600.1 - 0.023 15.0 0.7 8.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_endo_I PF05367.11 CEP13600.1 - 0.059 13.0 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Phage endonuclease I RST PF12174.8 CEP13600.1 - 0.13 12.2 0.0 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain PPV_E2_C PF00511.17 CEP13600.1 - 0.16 12.2 0.0 27 5.0 0.0 2.3 2 0 0 2 2 2 0 E2 (early) protein, C terminal Pkinase PF00069.25 CEP13602.1 - 3.9e-55 187.0 0.1 3.9e-55 187.0 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13602.1 - 9.2e-22 77.6 0.2 7.7e-21 74.5 0.1 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CEP13602.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEP13602.1 - 0.048 13.2 3.2 0.39 10.3 0.0 3.4 4 0 0 4 4 4 0 RIO1 family Choline_kinase PF01633.20 CEP13602.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.9 4 0 0 4 4 4 0 Choline/ethanolamine kinase RED_N PF07808.13 CEP13603.1 - 5.3e-42 144.0 23.7 5.3e-42 144.0 23.7 3.5 2 2 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 CEP13603.1 - 8.8e-20 71.3 12.7 8.8e-20 71.3 12.7 3.2 3 1 0 3 3 3 1 RED-like protein C-terminal region ANAPC4_WD40 PF12894.7 CEP13604.1 - 9.5e-11 41.9 3.3 4.3e-06 26.9 0.4 5.5 2 1 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP13604.1 - 3.4e-05 24.5 4.5 6.6 7.8 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 CEP13604.1 - 0.047 13.6 0.2 8.8 6.4 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat KH_1 PF00013.29 CEP13605.1 - 0.021 14.7 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 KH domain LegC3_N PF18654.1 CEP13605.1 - 0.63 9.2 3.9 1.3 8.2 3.9 1.4 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain zf-RVT PF13966.6 CEP13607.1 - 0.007 17.1 2.7 0.018 15.7 2.7 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Sin_N PF04801.13 CEP13609.1 - 0.015 14.6 10.1 0.018 14.2 10.1 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DUF3292 PF11696.8 CEP13609.1 - 0.35 9.2 5.9 0.39 9.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MMR1 PF08505.10 CEP13609.1 - 0.78 10.0 14.7 1.1 9.5 14.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 CEP13609.1 - 0.86 8.4 9.8 1.1 8.0 9.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 CEP13609.1 - 0.92 8.4 10.0 1.5 7.7 10.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) V_ATPase_I PF01496.19 CEP13609.1 - 1.8 6.4 9.9 2.2 6.1 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2347 PF09804.9 CEP13609.1 - 2.6 7.5 10.2 2.5 7.6 9.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DDHD PF02862.17 CEP13609.1 - 5.2 7.2 9.5 8.1 6.5 9.5 1.3 1 0 0 1 1 1 0 DDHD domain CREPT PF16566.5 CEP13609.1 - 8.7 6.5 17.6 5.6 7.1 14.7 1.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Chitin_synth_2 PF03142.15 CEP13610.1 - 4.5e-242 804.4 3.7 6.1e-242 803.9 3.7 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP13610.1 - 6.1e-99 332.1 1.7 3.8e-91 306.3 1.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 CEP13610.1 - 2.3e-18 65.8 0.0 1.8e-17 63.0 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CEP13610.1 - 3.7e-14 52.6 0.2 1.9e-07 31.1 0.0 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CEP13610.1 - 4.6e-12 46.3 3.3 1.5e-11 44.6 3.3 2.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP13610.1 - 8.5e-12 45.4 0.0 3.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEP13610.1 - 2.6e-05 24.1 0.0 0.0034 17.2 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP13610.1 - 0.003 17.1 0.2 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glutaredoxin PF00462.24 CEP13611.1 - 1.3e-23 83.0 0.0 2.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 CEP13611.1 - 0.0023 18.3 0.1 0.0036 17.7 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CEP13611.1 - 0.0024 18.3 0.3 0.0051 17.2 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 CEP13611.1 - 0.0033 17.8 0.0 0.0049 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 CEP13611.1 - 0.12 12.5 0.0 5.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DSBA PF01323.20 CEP13611.1 - 0.14 11.9 0.3 0.46 10.2 0.2 1.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain VASt PF16016.5 CEP13612.1 - 2.9e-30 105.7 2.0 2.9e-30 105.7 2.0 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CEP13612.1 - 2.3e-26 93.0 5.7 7e-26 91.4 5.7 1.9 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CEP13612.1 - 7.4e-08 32.9 0.3 7.4e-08 32.9 0.3 2.8 3 0 0 3 3 3 1 PH domain IMD PF08397.11 CEP13612.1 - 0.01 15.2 3.2 0.038 13.4 3.2 1.9 1 1 0 1 1 1 0 IRSp53/MIM homology domain GRAM PF02893.20 CEP13612.1 - 0.033 14.1 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 GRAM domain RhoGEF PF00621.20 CEP13612.1 - 0.053 13.8 3.3 0.037 14.3 0.5 2.3 2 0 0 2 2 2 0 RhoGEF domain VPR PF00522.18 CEP13612.1 - 0.098 12.7 2.5 0.19 11.7 0.4 2.5 2 0 0 2 2 2 0 VPR/VPX protein ATP-synt_B PF00430.18 CEP13612.1 - 0.12 12.4 0.0 0.12 12.4 0.0 3.4 4 0 0 4 4 4 0 ATP synthase B/B' CF(0) DUF4856 PF16148.5 CEP13612.1 - 0.57 9.1 8.8 0.095 11.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4856) Med5 PF08689.10 CEP13613.1 - 2.1e-16 59.1 0.6 5.6e-16 57.6 0.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit Med5 Med24_N PF11277.8 CEP13613.1 - 0.0013 16.9 0.1 0.64 8.0 0.0 3.1 3 0 0 3 3 3 2 Mediator complex subunit 24 N-terminal RED_N PF07808.13 CEP13613.1 - 0.61 9.6 3.4 26 4.3 0.1 3.5 3 0 0 3 3 3 0 RED-like protein N-terminal region Arrestin_C PF02752.22 CEP13614.1 - 2.1e-11 44.4 0.2 4.6e-07 30.3 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP13614.1 - 4.2e-07 30.1 0.0 9.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PEMT PF04191.13 CEP13615.1 - 1.6e-11 44.5 3.4 1.6e-11 44.5 3.4 2.2 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 CEP13615.1 - 1.5e-10 41.4 1.8 1.5e-10 41.4 1.8 2.1 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 CEP13615.1 - 2.2e-06 27.4 2.6 2.9e-06 27.0 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CEP13615.1 - 0.037 14.0 2.5 0.06 13.3 1.7 1.8 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3040 PF11239.8 CEP13615.1 - 0.091 13.0 4.1 2.8 8.3 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PIG-Y PF15159.6 CEP13615.1 - 0.5 11.3 12.9 1.1 10.3 10.5 2.7 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y adh_short PF00106.25 CEP13616.1 - 8.9e-38 129.7 0.0 1.1e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP13616.1 - 1.8e-28 99.7 0.0 2.2e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP13616.1 - 2.8e-11 43.6 0.1 4.9e-11 42.9 0.0 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 CEP13616.1 - 8.9e-08 32.2 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CEP13616.1 - 1.8e-06 27.6 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CEP13616.1 - 0.00034 20.3 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 CEP13616.1 - 0.0011 18.4 0.2 0.037 13.4 0.1 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 CEP13616.1 - 0.0043 16.2 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 CEP13616.1 - 0.11 12.8 0.1 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain AIG1 PF04548.16 CEP13617.1 - 0.16 11.2 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 AIG1 family 2-Hacid_dh_C PF02826.19 CEP13618.1 - 5.3e-51 172.5 0.0 7.3e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEP13618.1 - 2.2e-32 111.5 0.0 2.6e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 CEP13618.1 - 0.0052 17.3 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 CEP13618.1 - 0.0087 16.5 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 CEP13618.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 CEP13618.1 - 0.061 14.1 0.0 0.2 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold HTH_OrfB_IS605 PF12323.8 CEP13618.1 - 0.064 12.8 0.1 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain IlvN PF07991.12 CEP13618.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CDC13_N PF16853.5 CEP13619.1 - 2.9 7.4 7.2 4 6.9 7.2 1.1 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus CBFD_NFYB_HMF PF00808.23 CEP13620.1 - 5.9e-08 32.9 0.1 8.1e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP13620.1 - 2e-05 25.0 0.6 4.2e-05 23.9 0.6 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF5109 PF17134.4 CEP13620.1 - 0.044 13.7 0.1 0.069 13.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5109) PH PF00169.29 CEP13621.1 - 6.5e-06 26.6 2.6 7e-06 26.5 0.9 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CEP13621.1 - 0.00018 21.9 0.6 0.00018 21.9 0.6 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Nup54_C PF18437.1 CEP13621.1 - 0.068 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Beta_elim_lyase PF01212.21 CEP13622.1 - 6e-77 258.8 0.1 7.6e-77 258.5 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEP13622.1 - 4e-07 29.6 0.1 6.2e-07 28.9 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CEP13622.1 - 2.7e-06 26.9 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-RVT PF13966.6 CEP13623.1 - 0.00038 21.1 0.4 0.00038 21.1 0.4 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP13624.1 - 1.9e-06 27.6 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5327 PF17261.2 CEP13625.1 - 0.021 15.6 5.8 0.021 15.6 5.8 3.7 2 2 0 3 3 3 0 Family of unknown function (DUF5327) Abhydrolase_1 PF00561.20 CEP13627.1 - 9.9e-13 48.3 0.0 2.1e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP13627.1 - 2.6e-07 31.5 0.0 3.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP13627.1 - 5.1e-07 29.2 0.0 7.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CEP13627.1 - 5.4e-06 26.7 0.0 8.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CEP13627.1 - 1.7e-05 24.6 0.1 0.19 11.4 0.0 2.1 1 1 1 2 2 2 2 PGAP1-like protein DUF676 PF05057.14 CEP13627.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 CEP13627.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 CEP13627.1 - 0.034 12.9 0.0 0.069 11.8 0.0 1.6 1 1 0 1 1 1 0 Ndr family bZIP_1 PF00170.21 CEP13628.1 - 8.5e-11 41.8 6.7 8.5e-11 41.8 6.7 2.8 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 CEP13628.1 - 3.3e-06 27.1 6.0 3.3e-06 27.1 6.0 2.8 2 1 1 3 3 3 1 Basic region leucine zipper Aft1_OSA PF11785.8 CEP13628.1 - 0.00029 21.2 3.3 0.00029 21.2 3.3 2.4 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.17 CEP13628.1 - 0.029 14.9 3.5 0.029 14.9 3.5 2.2 2 1 0 2 2 2 0 bZIP Maf transcription factor DUF4711 PF15829.5 CEP13628.1 - 0.031 14.2 0.7 0.031 14.2 0.7 1.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4711) DDE_Tnp_1_7 PF13843.6 CEP13629.1 - 0.00018 20.9 0.0 0.0002 20.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Helitron_like_N PF14214.6 CEP13635.1 - 9.7e-21 74.8 0.0 2.8e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP13636.1 - 1.3e-55 189.1 0.0 2.8e-30 105.7 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.14 CEP13636.1 - 9.4e-08 30.5 0.0 1.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP13636.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain LEF-8 PF04941.12 CEP13636.1 - 0.091 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) ERp29 PF07749.12 CEP13637.1 - 0.022 15.6 0.0 0.023 15.6 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain bZIP_2 PF07716.15 CEP13638.1 - 5e-11 42.5 13.8 5e-11 42.5 13.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.9 CEP13638.1 - 0.0046 17.1 2.0 0.01 16.0 2.0 1.6 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.21 CEP13638.1 - 0.036 14.1 11.6 0.036 14.1 11.6 1.8 2 0 0 2 2 2 0 bZIP transcription factor RRM_3 PF08777.11 CEP13638.1 - 0.071 13.2 4.1 0.15 12.1 4.1 1.6 1 0 0 1 1 1 0 RNA binding motif GST_N_3 PF13417.6 CEP13639.1 - 6e-19 68.2 0.1 2.3e-18 66.3 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP13639.1 - 4.9e-14 52.4 0.0 8.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP13639.1 - 1.1e-10 41.7 0.0 4.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP13639.1 - 3.2e-07 30.5 0.0 7.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP13639.1 - 4.2e-07 29.9 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 CEP13639.1 - 7.4e-07 29.7 0.1 1.3e-06 29.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP13639.1 - 0.00054 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CEP13639.1 - 0.012 16.3 0.0 0.028 15.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain zf-RING_2 PF13639.6 CEP13640.1 - 9.8e-11 41.8 8.7 1.7e-10 41.1 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 CEP13640.1 - 3.2e-07 30.3 0.0 7.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 CEP13640.1 - 6e-07 29.2 8.7 1e-06 28.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEP13640.1 - 9e-07 28.5 7.5 2.1e-06 27.3 7.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEP13640.1 - 1.8e-06 27.7 7.2 3.1e-06 26.9 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP13640.1 - 2.1e-05 24.7 6.4 5.1e-05 23.5 6.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain SpoIIIAH PF12685.7 CEP13640.1 - 0.0012 18.8 3.5 1.8 8.3 0.0 2.3 2 0 0 2 2 2 2 SpoIIIAH-like protein SET PF00856.28 CEP13640.1 - 0.0052 17.2 0.3 0.034 14.5 0.1 2.1 2 0 0 2 2 2 1 SET domain zf-ANAPC11 PF12861.7 CEP13640.1 - 0.031 14.3 3.3 0.065 13.3 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DDHD PF02862.17 CEP13640.1 - 0.047 13.8 2.3 0.72 10.0 2.5 2.1 2 0 0 2 2 2 0 DDHD domain zf-C3HC4_3 PF13920.6 CEP13640.1 - 0.17 11.8 9.2 0.29 11.0 9.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 CEP13640.1 - 0.26 11.3 17.5 0.5 10.3 17.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 CEP13640.1 - 0.66 10.0 6.8 1.2 9.2 6.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP13640.1 - 1.5 8.9 8.3 3.5 7.7 8.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Spt20 PF12090.8 CEP13640.1 - 2.8 7.5 17.5 5.2 6.6 17.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF778 PF05608.12 CEP13640.1 - 3.3 8.0 6.3 0.85 10.0 3.2 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF778) DUF202 PF02656.15 CEP13641.1 - 9.9e-17 61.2 3.7 1e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B561 PF03188.16 CEP13641.1 - 0.093 12.9 3.6 0.15 12.2 3.6 1.5 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 zf-tcix PF14952.6 CEP13641.1 - 0.15 11.7 0.2 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF3021 PF11457.8 CEP13641.1 - 0.37 11.1 11.5 11 6.4 11.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) TPR_1 PF00515.28 CEP13642.1 - 0.016 15.0 1.5 0.088 12.7 0.8 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat BACK PF07707.15 CEP13642.1 - 0.048 13.8 0.9 0.086 12.9 0.6 1.6 1 1 1 2 2 2 0 BTB And C-terminal Kelch MMS1_N PF10433.9 CEP13643.1 - 1.9e-160 534.7 0.0 2.5e-160 534.3 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CEP13643.1 - 5.5e-92 308.5 0.0 1.8e-90 303.6 0.0 2.2 2 0 0 2 2 2 2 CPSF A subunit region DUF1241 PF06840.11 CEP13645.1 - 0.074 12.7 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) CoA_transf_3 PF02515.17 CEP13646.1 - 1.6e-69 234.8 0.0 5.6e-69 233.0 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III OrfB_Zn_ribbon PF07282.11 CEP13646.1 - 8.8e-05 22.4 0.6 0.00016 21.5 0.6 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CEBP_ZZ PF16366.5 CEP13646.1 - 0.1 12.9 1.0 0.18 12.1 1.0 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ArfGap PF01412.18 CEP13647.1 - 1.1e-25 90.0 1.0 1.1e-25 90.0 1.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PLDc_2 PF13091.6 CEP13648.1 - 1.9e-11 44.0 0.2 2.2e-06 27.6 0.0 3.7 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 CEP13648.1 - 1.2e-06 28.4 0.7 1.2e-06 28.4 0.7 2.7 3 0 0 3 3 3 1 Phospholipase D Active site motif PX PF00787.24 CEP13648.1 - 1.5e-06 28.2 0.0 5.2e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 PX domain Lin-8 PF03353.15 CEP13648.1 - 0.57 9.7 9.9 1.4 8.4 9.9 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 CEP13648.1 - 0.71 8.4 21.2 1.2 7.6 21.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 CEP13648.1 - 1.9 6.8 7.0 3.2 6.0 7.0 1.3 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 CEP13648.1 - 3 6.3 12.3 5.4 5.5 12.3 1.3 1 0 0 1 1 1 0 Macoilin family Nuf2 PF03800.14 CEP13649.1 - 8.5e-23 81.0 2.1 8.5e-23 81.0 2.1 2.1 2 0 0 2 2 2 1 Nuf2 family APG6_N PF17675.1 CEP13649.1 - 0.0032 18.0 34.0 0.044 14.3 13.8 2.8 2 0 0 2 2 2 2 Apg6 coiled-coil region AOX PF01786.17 CEP13649.1 - 0.084 12.4 0.5 1.5 8.3 0.0 2.3 1 1 0 2 2 2 0 Alternative oxidase DUF4373 PF14297.6 CEP13649.1 - 0.2 12.5 1.1 3.4 8.5 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4373) BAG PF02179.16 CEP13649.1 - 0.64 10.5 8.6 0.051 14.0 1.5 3.0 2 2 1 3 3 3 0 BAG domain PDZ_5 PF17817.1 CEP13650.1 - 0.022 15.1 0.8 0.038 14.3 0.6 1.6 1 1 1 2 2 2 0 PDZ domain Kelch_5 PF13854.6 CEP13651.1 - 6.5e-18 64.3 3.4 0.00024 21.0 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CEP13651.1 - 4.9e-17 61.2 2.6 0.00086 18.8 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEP13651.1 - 1.9e-15 56.1 9.4 0.0018 18.2 0.0 6.0 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 CEP13651.1 - 2.5e-15 56.7 0.2 8.2e-15 55.0 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 CEP13651.1 - 1.4e-14 53.8 1.3 0.0071 16.3 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP13651.1 - 1.6e-13 50.4 7.1 0.00051 20.2 0.0 5.8 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CEP13651.1 - 4.7e-11 42.7 19.6 0.026 14.8 0.2 6.7 6 2 1 7 7 7 4 Galactose oxidase, central domain SMYLE_N PF18615.1 CEP13651.1 - 0.17 11.4 1.5 0.25 10.9 1.5 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Dicty_REP PF05086.12 CEP13651.1 - 3.6 5.5 10.6 5 5.0 10.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 CEP13652.1 - 2.5e-71 240.1 0.2 2.5e-71 240.1 0.2 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13652.1 - 3.7e-49 167.3 0.2 3.7e-49 167.3 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 CEP13652.1 - 9.4e-22 77.1 0.0 2.7e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CEP13652.1 - 2.4e-05 23.8 0.1 2.4e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP13652.1 - 0.00012 21.0 16.3 0.00081 18.3 16.2 2.0 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP13652.1 - 0.00034 19.7 3.4 0.00058 18.9 3.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF5560 PF17715.1 CEP13652.1 - 0.046 13.2 0.4 0.24 10.9 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5560) APH PF01636.23 CEP13652.1 - 0.056 13.4 2.7 0.16 11.9 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family RR_TM4-6 PF06459.12 CEP13652.1 - 1 9.1 11.5 2 8.1 11.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 dsRBD2 PF17842.1 CEP13652.1 - 2.2 8.5 5.3 6 7.1 5.3 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 XRN_M PF17846.1 CEP13652.1 - 7 5.5 14.3 13 4.6 14.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain AAA_11 PF13086.6 CEP13652.1 - 8.7 6.0 13.3 15 5.3 13.3 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 CEP13652.1 - 9.1 4.0 9.3 14 3.4 9.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NCBP3 PF10309.9 CEP13653.1 - 4.7e-17 61.6 0.0 9.1e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 STIMATE PF12400.8 CEP13654.1 - 6.4e-40 136.6 10.6 9.2e-40 136.1 10.6 1.2 1 0 0 1 1 1 1 STIMATE family Blt1 PF12754.7 CEP13654.1 - 0.0071 16.7 0.1 0.0096 16.2 0.1 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Hanta_G2 PF01561.16 CEP13654.1 - 2.1 6.9 4.0 3.3 6.2 4.0 1.3 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 WD40 PF00400.32 CEP13655.1 - 0.0017 19.1 3.5 1.1 10.2 0.0 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13655.1 - 0.14 12.5 0.0 6.5 7.1 0.0 3.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP13656.1 - 6.2e-16 58.5 14.2 0.0042 17.9 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13656.1 - 2.1e-07 31.1 1.5 0.00061 20.0 0.6 4.2 2 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP13656.1 - 2e-06 26.8 0.2 1.9e-05 23.6 0.1 2.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 UPF0128 PF03673.13 CEP13656.1 - 0.07 12.6 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) AA_permease PF00324.21 CEP13657.1 - 1.7e-114 383.1 43.7 2.1e-114 382.8 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP13657.1 - 7e-35 120.7 44.6 8.7e-35 120.4 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease PgaD PF13994.6 CEP13657.1 - 0.0054 16.8 0.4 1.6 8.8 0.0 3.1 3 0 0 3 3 3 2 PgaD-like protein Mito_carr PF00153.27 CEP13658.1 - 8.5e-64 211.5 4.1 6.1e-21 74.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP13658.1 - 0.025 13.7 0.2 0.34 10.0 0.1 2.3 2 1 0 2 2 2 0 Gammaproteobacterial serine protease CWC25 PF12542.8 CEP13659.1 - 1.3e-24 87.0 3.5 1.3e-24 87.0 3.5 3.1 2 1 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 CEP13659.1 - 6.8e-15 55.0 12.9 6.8e-15 55.0 12.9 3.9 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.10 CEP13659.1 - 0.02 15.7 14.4 0.02 15.7 14.4 3.2 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Lyase_1 PF00206.20 CEP13660.1 - 3.4e-100 335.4 0.0 4.7e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CEP13660.1 - 7.4e-24 84.3 0.1 1.6e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Pkinase PF00069.25 CEP13661.1 - 9.1e-53 179.3 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13661.1 - 3.9e-35 121.4 0.0 4.9e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP13661.1 - 7.8e-06 25.4 0.2 1.5e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEP13661.1 - 0.05 13.2 0.1 0.43 10.2 0.1 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RNA_Me_trans PF04252.13 CEP13662.1 - 1.5e-78 263.0 0.0 1.7e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Parvo_coat PF00740.18 CEP13663.1 - 0.033 12.9 0.0 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GPI-anchored PF10342.9 CEP13663.1 - 0.056 14.2 0.2 0.12 13.1 0.2 1.6 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 CEP13663.1 - 0.12 11.8 0.4 3.8 6.9 0.2 2.4 1 1 1 2 2 2 0 High-affinity nitrate transporter accessory Asp PF00026.23 CEP13664.1 - 1.6e-83 280.7 3.5 1.9e-83 280.5 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP13664.1 - 3.1e-10 40.6 1.8 4.5e-08 33.5 1.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP13664.1 - 0.00017 21.4 0.0 0.00047 20.0 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CEP13664.1 - 0.012 16.2 0.0 8.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 CEP13664.1 - 0.044 14.4 0.5 8.6 7.0 0.1 3.1 3 1 1 4 4 4 0 gag-polyprotein putative aspartyl protease RBFA PF02033.18 CEP13665.1 - 4.3e-14 52.8 0.0 7.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Ribosome-binding factor A DUF2334 PF10096.9 CEP13665.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Ribosomal_L24e PF01246.20 CEP13666.1 - 1.1e-13 51.1 1.2 1.4e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e mit_SMPDase PF14724.6 CEP13667.1 - 4.6e-05 21.6 0.1 0.0018 16.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase Peptidase_M24 PF00557.24 CEP13668.1 - 1.3e-51 175.3 0.6 1.8e-51 174.9 0.6 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CEP13668.1 - 1.2e-09 38.9 0.0 2.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.24 CEP13669.1 - 2.4e-12 46.5 17.1 1.2e-10 40.9 17.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP13669.1 - 0.00012 21.1 17.7 0.00038 19.5 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ca_hom_mod PF14798.6 CEP13669.1 - 0.73 8.9 4.1 0.43 9.6 0.7 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator OTCace PF00185.24 CEP13670.1 - 7.9e-51 172.2 0.0 1.2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CEP13670.1 - 4.6e-47 159.7 0.0 8.2e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OCD_Mu_crystall PF02423.15 CEP13670.1 - 0.053 12.4 0.6 0.08 11.9 0.6 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Lustrin_cystein PF14625.6 CEP13670.1 - 0.084 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Aldo_ket_red PF00248.21 CEP13671.1 - 4.1e-43 147.7 0.0 5.3e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.22 CEP13672.1 - 0.012 16.0 0.0 2.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Thioesterase superfamily HSP70 PF00012.20 CEP13674.1 - 2.2e-84 283.8 21.8 2.2e-84 283.8 21.8 2.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEP13674.1 - 1.1e-05 24.5 3.9 0.00012 21.0 3.9 2.1 1 1 0 1 1 1 1 MreB/Mbl protein V_ATPase_I PF01496.19 CEP13674.1 - 9.3 4.0 17.0 4.3 5.1 8.5 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4949 PF16307.5 CEP13675.1 - 0.092 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) Calcipressin PF04847.12 CEP13676.1 - 0.032 14.0 0.2 0.048 13.4 0.2 1.2 1 0 0 1 1 1 0 Calcipressin DHHW PF14286.6 CEP13676.1 - 0.17 11.2 2.0 0.23 10.7 2.0 1.1 1 0 0 1 1 1 0 DHHW protein rve PF00665.26 CEP13677.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13677.1 - 1.2e-17 63.7 0.2 1.8e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP13677.1 - 0.00033 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.15 CEP13677.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Mu transposase MRP-L20 PF12824.7 CEP13681.1 - 0.02 15.0 0.3 0.022 14.9 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 DUF2204 PF09970.9 CEP13683.1 - 0.049 13.3 0.4 0.42 10.2 0.1 2.2 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Exo_endo_phos_2 PF14529.6 CEP13684.1 - 2.9e-11 43.3 1.0 8.7e-11 41.7 1.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_hydro_76 PF03663.14 CEP13684.1 - 0.018 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 CotH PF08757.11 CEP13687.1 - 3e-34 119.0 0.0 4.8e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 CotH kinase protein OMPdecase PF00215.24 CEP13688.1 - 2.5e-80 269.3 0.0 2.9e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family EXS PF03124.14 CEP13689.1 - 1.5e-65 221.7 17.1 1.7e-65 221.6 17.1 1.0 1 0 0 1 1 1 1 EXS family Tfb4 PF03850.14 CEP13690.1 - 0.013 15.0 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 G-alpha PF00503.20 CEP13691.1 - 2.7e-91 306.4 6.2 3.1e-91 306.2 6.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP13691.1 - 1e-09 38.1 0.2 3.6e-09 36.3 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family PhoPQ_related PF10142.9 CEP13691.1 - 0.003 16.3 0.0 0.0041 15.8 0.0 1.4 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein SMP_C2CD2L PF18696.1 CEP13691.1 - 0.1 12.4 0.3 1.4 8.7 0.0 2.3 3 0 0 3 3 3 0 Synaptotagmin-like, mitochondrial and lipid-binding domain S4 PF01479.25 CEP13692.1 - 4.3e-12 45.5 1.2 4.3e-12 45.5 1.2 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CEP13692.1 - 0.00017 22.4 0.0 0.0003 21.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CEP13693.1 - 1e-48 163.4 4.3 1.5e-48 162.8 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e LETM1 PF07766.13 CEP13694.1 - 2.1e-37 128.9 6.2 6.3e-22 78.2 0.6 2.1 1 1 1 2 2 2 2 LETM1-like protein SAP PF02037.27 CEP13694.1 - 0.043 13.6 0.3 10 6.0 0.0 3.0 3 0 0 3 3 3 0 SAP domain DUF5327 PF17261.2 CEP13695.1 - 3.4 8.4 0.0 3.4 8.4 0.0 3.9 3 2 1 4 4 4 0 Family of unknown function (DUF5327) tRNA-synt_1e PF01406.19 CEP13696.1 - 6.3e-135 449.3 3.4 8.4e-135 448.9 1.7 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CEP13696.1 - 3.4e-09 36.0 5.1 1.9e-06 26.9 0.2 2.9 2 1 1 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CEP13696.1 - 0.00019 21.8 2.6 0.00023 21.6 0.2 2.4 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 CEP13696.1 - 0.00028 19.3 0.0 0.00099 17.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 CEP13696.1 - 0.0012 17.8 3.0 0.0066 15.4 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 CEP13696.1 - 0.0034 16.4 0.1 0.073 12.0 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) PEP_mutase PF13714.6 CEP13696.1 - 0.067 12.6 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase RPA_interact_M PF14767.6 CEP13696.1 - 0.11 13.1 2.8 0.98 10.0 0.4 2.8 2 0 0 2 2 2 0 Replication protein A interacting middle Ribonuc_red_sm PF00268.21 CEP13697.1 - 3.2e-121 404.1 3.3 4e-121 403.8 3.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Glyco_transf_15 PF01793.16 CEP13698.1 - 3.3e-117 391.4 11.0 4.1e-117 391.1 11.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DAPDH_C PF16654.5 CEP13698.1 - 0.0044 16.9 0.1 0.0079 16.0 0.1 1.4 1 0 0 1 1 1 1 Diaminopimelic acid dehydrogenase C-terminal domain VTC PF09359.10 CEP13699.1 - 4e-67 226.5 0.4 8.8e-67 225.4 0.4 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CEP13699.1 - 1.2e-14 55.0 20.3 4.1e-07 30.3 0.3 4.3 3 1 1 4 4 4 4 SPX domain DUF202 PF02656.15 CEP13699.1 - 1.5e-11 44.5 0.5 3.1e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MetOD2 PF18548.1 CEP13699.1 - 0.013 15.6 1.7 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 Metanogen output domain 2 RAB3GAP2_N PF14655.6 CEP13699.1 - 0.03 13.6 0.9 0.05 12.9 0.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus COOH-NH2_lig PF14395.6 CEP13699.1 - 0.29 10.3 0.9 0.58 9.3 0.0 1.8 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Cdh1_DBD_1 PF18196.1 CEP13699.1 - 1.3 9.3 6.2 2 8.8 0.1 3.1 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Peptidase_M20 PF01546.28 CEP13700.1 - 1e-27 97.2 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CEP13700.1 - 7e-13 48.8 20.0 1.1e-06 29.2 0.4 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.14 CEP13700.1 - 2.9e-05 23.9 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 CEP13700.1 - 0.00064 18.5 2.4 0.19 10.3 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 TFIID_20kDa PF03847.13 CEP13702.1 - 5.3e-35 119.7 0.7 9.2e-35 119.0 0.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CEP13702.1 - 3.6e-05 24.0 0.1 7.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP13702.1 - 9.9e-05 22.7 0.1 9.9e-05 22.7 0.1 2.9 3 1 1 4 4 4 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CEP13702.1 - 0.0034 17.5 0.0 0.0034 17.5 0.0 2.5 2 1 1 3 3 3 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CEP13702.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Pkinase PF00069.25 CEP13703.1 - 3e-48 164.5 0.1 4.4e-48 163.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13703.1 - 2.3e-17 63.1 0.0 3.1e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13703.1 - 0.0002 20.8 0.1 0.00041 19.7 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP13703.1 - 0.034 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CPSase_L_D2 PF02786.17 CEP13704.1 - 3.6e-76 255.4 0.0 6.2e-76 254.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEP13704.1 - 2.4e-43 147.2 0.0 5.3e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP13704.1 - 2.1e-30 105.0 0.0 6.2e-29 100.3 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEP13704.1 - 4.2e-17 61.7 1.1 9.8e-17 60.6 1.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 CEP13704.1 - 1.1e-12 48.4 0.0 2.9e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CEP13704.1 - 3.5e-10 39.8 0.0 7.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CEP13704.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CEP13704.1 - 1.8e-07 30.8 0.2 0.0024 17.6 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 CEP13704.1 - 0.00016 21.0 0.6 0.24 10.6 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CEP13704.1 - 0.00042 21.0 2.5 0.046 14.4 0.1 3.4 3 0 0 3 3 3 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 CEP13704.1 - 0.077 12.2 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Glyco_hydro_65C PF03633.15 CEP13704.1 - 0.17 11.8 0.1 1 9.3 0.0 2.3 3 0 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain Cas1_AcylT PF07779.12 CEP13705.1 - 1.8e-129 432.8 35.6 2.3e-129 432.4 35.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 CEP13705.1 - 0.0044 16.8 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p XPG_I_2 PF12813.7 CEP13706.1 - 0.079 12.4 0.0 0.28 10.6 0.0 1.8 1 1 0 1 1 1 0 XPG domain containing dCMP_cyt_deam_1 PF00383.23 CEP13707.1 - 6.9e-24 83.6 1.4 9.3e-24 83.2 0.6 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP13707.1 - 1.4e-12 47.5 0.1 2.2e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CEP13707.1 - 0.029 14.5 0.2 0.058 13.5 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 AAA_18 PF13238.6 CEP13707.1 - 0.057 14.0 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain APOBEC4_like PF18774.1 CEP13707.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Myosin_head PF00063.21 CEP13708.1 - 1.5e-271 902.5 8.8 1.5e-271 902.5 8.8 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 CEP13708.1 - 6e-08 32.4 0.8 1.7e-07 31.0 0.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Lebercilin PF15619.6 CEP13708.1 - 3.6e-05 23.5 44.9 0.00012 21.8 13.5 3.0 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Spc29 PF17082.5 CEP13708.1 - 0.001 19.0 26.3 0.21 11.4 1.2 3.9 1 1 2 3 3 3 3 Spindle Pole Component 29 Fib_alpha PF08702.10 CEP13708.1 - 0.0078 16.4 14.5 0.0078 16.4 14.5 5.5 3 1 3 6 6 6 1 Fibrinogen alpha/beta chain family AAA_22 PF13401.6 CEP13708.1 - 0.16 12.2 3.0 0.26 11.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CEP13708.1 - 0.32 11.4 0.0 0.32 11.4 0.0 3.7 2 1 1 3 3 2 0 AAA ATPase domain DUF16 PF01519.16 CEP13708.1 - 2.2 8.8 39.4 0.84 10.1 5.2 4.8 1 1 3 4 4 4 0 Protein of unknown function DUF16 ATG16 PF08614.11 CEP13708.1 - 2.7 8.2 62.5 0.43 10.8 17.4 4.2 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CEP13708.1 - 4.9 7.2 53.4 0.38 10.8 25.7 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ERM PF00769.19 CEP13708.1 - 7.7 6.3 56.6 0.49 10.2 19.0 3.0 1 1 0 2 2 2 0 Ezrin/radixin/moesin family DDE_3 PF13358.6 CEP13710.1 - 3.3e-14 52.9 0.1 5.5e-06 26.2 0.1 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease Y_phosphatase PF00102.27 CEP13711.1 - 2.3e-66 223.7 4.3 2.3e-66 223.7 4.3 2.4 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CEP13711.1 - 7.7e-09 36.0 0.1 2.3e-07 31.3 0.0 3.2 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.20 CEP13711.1 - 0.001 18.9 0.2 0.0034 17.2 0.2 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Coagulin PF02035.15 CEP13711.1 - 0.095 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Coagulin Vip3A_N PF12495.8 CEP13711.1 - 0.11 12.4 0.3 0.21 11.5 0.3 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal NAD_binding_10 PF13460.6 CEP13712.1 - 0.00049 20.0 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP13712.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family DUSP PF06337.12 CEP13712.1 - 0.021 15.4 1.5 0.49 11.0 1.5 3.1 1 1 0 1 1 1 0 DUSP domain TFIIS_M PF07500.14 CEP13712.1 - 0.042 14.3 0.0 0.09 13.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain Sacchrp_dh_NADP PF03435.18 CEP13712.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NIF3 PF01784.18 CEP13713.1 - 3.1e-70 236.6 0.0 3.7e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Acyl-CoA_dh_1 PF00441.24 CEP13714.1 - 1e-45 155.6 3.0 1e-45 155.6 3.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEP13714.1 - 8.9e-27 94.0 0.7 3.2e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEP13714.1 - 7.1e-22 77.4 0.1 1.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEP13714.1 - 2.2e-19 70.1 0.3 2.2e-19 70.1 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Exo_endo_phos PF03372.23 CEP13716.1 - 6.9e-17 61.7 0.0 1.4e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CEP13716.1 - 1.8e-07 31.4 13.7 0.0015 18.9 1.7 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP13716.1 - 3.9e-06 26.5 10.0 2.7e-05 23.9 3.8 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CEP13716.1 - 0.15 12.7 7.5 46 5.1 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat K_channel_TID PF07941.11 CEP13716.1 - 9.1 6.8 10.8 25 5.4 10.8 1.7 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Sec6 PF06046.13 CEP13718.1 - 3.5e-147 491.2 10.1 5.2e-147 490.7 10.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 SLIDE PF09111.10 CEP13718.1 - 0.03 14.3 2.9 0.04 13.9 0.7 2.4 2 0 0 2 2 2 0 SLIDE NPV_P10 PF05531.12 CEP13718.1 - 0.38 11.2 3.7 29 5.2 0.5 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4286 PF14114.6 CEP13718.1 - 0.63 10.6 4.1 2 9.0 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4286) OrfB_Zn_ribbon PF07282.11 CEP13719.1 - 1.9e-07 30.9 1.1 3.7e-07 30.0 1.1 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zinc_ribbon_12 PF11331.8 CEP13719.1 - 0.11 12.3 2.0 0.27 11.0 2.0 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon domain PLDc PF00614.22 CEP13720.1 - 2.3e-18 65.5 1.8 1.8e-10 40.6 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEP13720.1 - 2e-17 63.3 0.3 1.1e-07 31.8 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain DDE_3 PF13358.6 CEP13721.1 - 0.0028 17.4 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP13721.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_7 PF03492.15 CEP13725.1 - 0.034 13.4 0.2 0.048 12.9 0.2 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase NDT80_PhoG PF05224.12 CEP13726.1 - 2e-39 135.7 0.0 4.5e-39 134.6 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AnkUBD PF18418.1 CEP13731.1 - 0.13 12.4 0.1 0.42 10.8 0.1 1.9 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain DUF2070 PF09843.9 CEP13731.1 - 0.17 10.1 21.3 0.26 9.5 21.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PWI PF01480.17 CEP13732.1 - 9.8e-31 105.9 0.1 1.9e-30 105.0 0.1 1.5 1 0 0 1 1 1 1 PWI domain ketoacyl-synt PF00109.26 CEP13732.1 - 0.17 11.4 0.1 0.69 9.4 0.2 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain CAP_GLY PF01302.25 CEP13733.1 - 5.8e-22 77.5 0.2 9.6e-22 76.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.31 CEP13733.1 - 3.9e-10 40.0 0.4 8.9e-10 38.8 0.2 1.7 2 0 0 2 2 2 1 BTB/POZ domain Adeno_terminal PF02459.15 CEP13733.1 - 0.55 8.6 2.2 0.93 7.8 2.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Vac7 PF12751.7 CEP13734.1 - 1.4e-08 34.6 0.1 1.4e-08 34.6 0.1 3.1 2 1 1 3 3 3 3 Vacuolar segregation subunit 7 Pyridox_oxase_2 PF12766.7 CEP13735.1 - 1.2e-26 93.2 0.9 3.4e-25 88.6 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 CEP13735.1 - 3.4e-10 40.0 0.0 5.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CEP13735.1 - 0.0027 17.3 0.5 0.0051 16.4 0.5 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like RAC_head PF16717.5 CEP13735.1 - 0.026 15.5 0.3 0.093 13.7 0.2 1.9 2 0 0 2 2 2 0 Ribosome-associated complex head domain HTH_17 PF12728.7 CEP13736.1 - 6.9e-06 26.2 0.0 0.024 14.8 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 CEP13736.1 - 2.1e-05 24.2 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 CEP13736.1 - 2.9e-05 24.1 0.1 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP13736.1 - 0.00027 20.9 0.1 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP13736.1 - 0.041 13.3 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 CEP13736.1 - 0.057 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MARVEL PF01284.23 CEP13738.1 - 0.0034 17.4 13.5 0.0063 16.6 13.5 1.4 1 1 0 1 1 1 1 Membrane-associating domain RhodobacterPufX PF11511.8 CEP13738.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.7 4 0 0 4 4 4 0 Intrinsic membrane protein PufX DUF2975 PF11188.8 CEP13738.1 - 7.5 6.4 9.2 9.5 6.1 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF588 PF04535.12 CEP13739.1 - 0.011 15.6 2.1 0.014 15.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) IL31 PF15209.6 CEP13739.1 - 0.037 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 31 ThiF PF00899.21 CEP13740.1 - 1.1e-52 178.9 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CEP13740.1 - 4.2e-12 46.5 0.1 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain RVT_1 PF00078.27 CEP13743.1 - 5.9e-11 42.3 1.7 7.3e-11 42.0 0.4 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIID_30kDa PF03540.13 CEP13743.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit PfkB PF00294.24 CEP13744.1 - 1e-20 74.3 0.1 2.9e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PIP5K PF01504.18 CEP13745.1 - 4.8e-99 331.0 0.4 6.9e-99 330.5 0.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FMN_red PF03358.15 CEP13746.1 - 1.3e-11 44.5 0.0 1.3e-11 44.5 0.0 1.9 3 0 0 3 3 3 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEP13746.1 - 0.00028 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CEP13747.1 - 1.6e-14 53.9 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEP13747.1 - 2.5e-08 33.9 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CEP13747.1 - 0.0086 16.3 0.1 0.19 11.9 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin BRCA-2_OB1 PF09103.10 CEP13748.1 - 3e-31 107.9 0.1 6.1e-31 106.9 0.1 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CEP13748.1 - 1.5e-11 44.3 1.1 8.8e-11 41.8 0.7 2.3 1 1 1 2 2 2 1 BRCA2, helical Rep-A_N PF04057.12 CEP13748.1 - 0.00018 21.5 0.1 0.00047 20.1 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain BRCA2 PF00634.18 CEP13748.1 - 0.046 13.4 3.4 4.8 7.0 0.1 3.0 3 0 0 3 3 3 0 BRCA2 repeat BRCA-2_OB3 PF09104.10 CEP13748.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TolA_bind_tri PF16331.5 CEP13748.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation Sds3 PF08598.11 CEP13749.1 - 1.1e-10 41.9 16.2 1.1e-10 41.9 16.2 2.1 1 1 1 2 2 2 1 Sds3-like Roughex PF06020.11 CEP13749.1 - 0.86 8.6 20.9 0.041 13.0 6.7 2.1 2 0 0 2 2 2 0 Drosophila roughex protein ATP12 PF07542.11 CEP13750.1 - 1.2e-40 138.6 0.7 1.9e-40 137.9 0.7 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF438 PF04282.13 CEP13750.1 - 0.0097 15.8 0.5 0.06 13.3 0.5 2.1 1 1 0 1 1 1 1 Family of unknown function (DUF438) NDC10_II PF16787.5 CEP13751.1 - 4.5e-49 167.2 0.0 5.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP13751.1 - 6.5e-11 42.4 0.1 1.9e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Baculo_PEP_C PF04513.12 CEP13751.1 - 0.047 13.7 3.4 0.092 12.8 3.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDPS PF16715.5 CEP13751.1 - 0.12 12.0 0.9 0.21 11.2 0.9 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase TolA_bind_tri PF16331.5 CEP13751.1 - 0.2 11.8 1.1 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation HTH_24 PF13412.6 CEP13752.1 - 6.4e-05 22.4 0.2 0.00047 19.7 0.1 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 CEP13752.1 - 0.0011 18.8 0.0 0.009 15.9 0.0 2.4 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 CEP13752.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 CEP13752.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_1 PF00126.27 CEP13752.1 - 0.0029 17.5 0.1 0.0075 16.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Mga PF05043.13 CEP13752.1 - 0.003 18.1 0.5 0.0063 17.1 0.5 1.5 1 0 0 1 1 1 1 Mga helix-turn-helix domain DUF134 PF02001.16 CEP13752.1 - 0.0046 17.5 0.2 0.014 15.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF134 HTH_23 PF13384.6 CEP13752.1 - 0.0054 16.5 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 CEP13752.1 - 0.0072 16.4 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 CEP13752.1 - 0.0089 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 CEP13752.1 - 0.011 15.4 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_32 PF13565.6 CEP13752.1 - 0.012 16.2 0.0 0.036 14.7 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain PqqD PF05402.12 CEP13752.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) HTH_Tnp_ISL3 PF13542.6 CEP13752.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 CEP13752.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_AraC PF00165.23 CEP13752.1 - 0.051 13.7 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family MarR_2 PF12802.7 CEP13752.1 - 0.054 13.4 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_6 PF01418.17 CEP13752.1 - 0.054 13.5 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_29 PF13551.6 CEP13752.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_30 PF13556.6 CEP13752.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_DeoR PF08220.12 CEP13752.1 - 0.099 12.4 0.0 5.5 6.8 0.0 2.4 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain Stork_head PF10264.9 CEP13752.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain CBS PF00571.28 CEP13753.1 - 3.3e-27 94.7 2.2 5.3e-08 33.2 0.0 4.8 4 1 0 4 4 4 4 CBS domain CoA_binding_2 PF13380.6 CEP13753.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain HlyIII PF03006.20 CEP13754.1 - 6e-61 206.0 21.9 7.8e-61 205.6 21.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 CEP13754.1 - 0.077 13.1 0.3 0.24 11.5 0.3 1.9 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TFIID-18kDa PF02269.16 CEP13755.1 - 7e-31 106.1 0.3 1.8e-30 104.8 0.3 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromodomain PF00439.25 CEP13756.1 - 8e-23 80.3 0.1 1.7e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 Bromodomain DUF3512 PF12024.8 CEP13756.1 - 0.0079 15.7 0.0 0.0079 15.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3512) Zn_clus PF00172.18 CEP13757.1 - 2.7e-07 30.6 9.0 2.7e-07 30.6 9.0 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM72 PF14976.6 CEP13758.1 - 8.5e-17 61.6 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 FAM72 protein LRRCT PF01463.24 CEP13759.1 - 0.052 14.1 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain Sec62 PF03839.16 CEP13760.1 - 0.28 10.6 0.9 0.55 9.7 0.9 1.4 1 1 0 1 1 1 0 Translocation protein Sec62 Avl9 PF09794.9 CEP13761.1 - 3.5e-137 457.1 0.1 7.6e-137 456.0 0.0 1.6 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 CEP13761.1 - 2.6e-11 43.5 0.1 3.2e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 CEP13761.1 - 1.5e-08 34.6 8.2 3.4e-06 26.9 0.0 4.9 2 2 1 3 3 3 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CEP13761.1 - 0.11 13.0 0.8 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 CEP13761.1 - 0.15 12.0 0.7 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 DENN (AEX-3) domain Presenilin PF01080.17 CEP13762.1 - 0.15 10.8 14.7 0.33 9.7 14.7 1.5 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CEP13762.1 - 4.9 6.4 12.6 0.5 9.7 8.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RIO1 PF01163.22 CEP13763.1 - 7.9e-46 156.0 0.0 7.9e-46 156.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 CEP13763.1 - 2.3e-36 123.9 0.9 1e-35 121.8 0.2 2.5 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.23 CEP13763.1 - 8e-10 39.0 0.0 6.9e-05 22.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEP13763.1 - 1.6e-06 27.7 0.0 0.028 13.8 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Glutaredoxin2_C PF04399.13 CEP13763.1 - 0.14 12.0 0.8 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Drc1-Sld2 PF11719.8 CEP13763.1 - 0.45 10.0 31.9 0.64 9.5 31.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein WD40 PF00400.32 CEP13765.1 - 2.1e-09 37.9 2.6 0.00068 20.4 0.1 5.8 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13765.1 - 1.5e-07 31.6 0.1 2.8 8.3 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP13765.1 - 3.3e-05 23.4 0.0 0.0059 16.0 0.0 2.3 1 1 0 2 2 2 2 WD40-like domain Hira PF07569.11 CEP13765.1 - 0.0044 16.8 0.0 5.9 6.6 0.0 3.4 2 1 0 2 2 2 2 TUP1-like enhancer of split PQQ_2 PF13360.6 CEP13765.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 CEP13765.1 - 0.03 13.0 0.0 0.75 8.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 COBRA PF04833.15 CEP13765.1 - 0.044 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 COBRA-like protein PQQ_3 PF13570.6 CEP13765.1 - 0.16 12.5 0.0 0.86 10.2 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain CAF1C_H4-bd PF12265.8 CEP13766.1 - 4.1e-27 94.2 0.7 1.3e-26 92.7 0.7 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CEP13766.1 - 1.1e-25 89.4 11.7 1.1e-05 26.0 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF908 PF06012.12 CEP13766.1 - 0.69 9.3 9.0 1.6 8.0 9.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) EOS1 PF12326.8 CEP13766.1 - 0.73 9.7 2.5 1.5 8.7 2.5 1.6 1 0 0 1 1 1 0 N-glycosylation protein ANF_receptor PF01094.28 CEP13767.1 - 1.1e-35 123.5 0.3 1.7e-35 122.7 0.3 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 CEP13767.1 - 7.6e-25 88.0 22.5 1.3e-24 87.3 22.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 CEP13767.1 - 2.2e-15 57.2 1.0 3.3e-15 56.6 1.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Aminotran_1_2 PF00155.21 CEP13768.1 - 2.5e-38 132.2 0.0 3.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP13768.1 - 0.0054 16.0 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CEP13768.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V APG6_N PF17675.1 CEP13769.1 - 0.0016 19.0 21.9 0.0016 19.0 21.9 16.4 6 4 8 15 15 15 6 Apg6 coiled-coil region MAD PF05557.13 CEP13769.1 - 0.0016 16.9 24.3 0.0016 16.9 24.3 8.0 2 1 5 8 8 8 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 CEP13769.1 - 0.0055 16.8 24.7 0.0055 16.8 24.7 16.6 5 5 11 17 17 17 4 TPR/MLP1/MLP2-like protein SOGA PF11365.8 CEP13769.1 - 0.016 16.3 1.8 0.016 16.3 1.8 15.6 6 4 12 19 19 19 0 Protein SOGA zf-CCCH_7 PF18586.1 CEP13769.1 - 0.078 13.3 1.8 0.28 11.5 0.1 3.0 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 WD40_alt PF14077.6 CEP13769.1 - 0.083 12.8 3.8 11 6.0 0.0 4.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif Pox_A_type_inc PF04508.12 CEP13769.1 - 0.099 12.5 10.9 0.38 10.7 0.1 6.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat HEAT_2 PF13646.6 CEP13770.1 - 4.3e-26 91.1 1.9 1.9e-07 31.3 0.0 8.6 7 2 2 9 9 8 4 HEAT repeats HEAT PF02985.22 CEP13770.1 - 3.3e-25 86.0 14.7 5.5e-05 23.1 0.1 11.7 12 0 0 12 12 11 4 HEAT repeat HEAT_EZ PF13513.6 CEP13770.1 - 1.4e-23 82.9 12.0 6.3e-08 33.0 0.3 10.8 9 2 4 13 13 12 4 HEAT-like repeat Cnd1 PF12717.7 CEP13770.1 - 6.8e-14 52.2 0.3 2.3e-06 27.7 0.0 4.2 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEP13770.1 - 9.8e-12 45.3 5.9 0.0037 17.8 0.0 7.9 7 1 3 10 10 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEP13770.1 - 5.7e-09 35.9 0.3 0.0082 15.7 0.0 6.1 5 2 2 7 7 7 2 CLASP N terminal IBN_N PF03810.19 CEP13770.1 - 6.4e-09 35.6 3.1 4.9e-08 32.8 0.2 4.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CEP13770.1 - 4.4e-08 33.2 3.7 0.028 14.3 0.0 6.8 6 2 1 7 7 7 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 CEP13770.1 - 4.8e-08 32.0 2.4 0.012 14.3 0.1 4.3 4 1 1 5 5 5 2 Adaptin N terminal region RIX1 PF08167.12 CEP13770.1 - 4.9e-07 29.7 0.0 0.86 9.3 0.0 4.3 2 1 1 3 3 3 3 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 CEP13770.1 - 2.1e-06 27.1 0.2 0.012 14.8 0.0 3.7 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 CEP13770.1 - 1.1e-05 25.5 0.6 0.45 10.7 0.0 5.7 6 1 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 CEP13770.1 - 1.6e-05 24.6 0.2 0.24 10.9 0.1 4.0 3 1 1 4 4 4 2 Tti2 family CTD_bind PF04818.13 CEP13770.1 - 0.001 19.8 0.1 42 5.1 0.0 4.7 4 0 0 4 4 3 0 RNA polymerase II-binding domain. NUC173 PF08161.12 CEP13770.1 - 0.0048 16.6 0.3 6.9 6.3 0.0 4.6 3 1 1 4 4 4 1 NUC173 domain UNC45-central PF11701.8 CEP13770.1 - 0.014 15.4 2.1 1.5 8.7 0.1 4.7 3 1 3 6 6 6 0 Myosin-binding striated muscle assembly central SMK-1 PF04802.15 CEP13770.1 - 0.11 12.3 0.6 0.82 9.5 0.2 2.6 1 1 1 2 2 2 0 Component of IIS longevity pathway SMK-1 Arm PF00514.23 CEP13770.1 - 0.94 9.6 3.8 42 4.4 0.1 5.2 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat COX15-CtaA PF02628.15 CEP13771.1 - 1.4e-107 359.5 5.3 1.8e-107 359.2 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein HTH_7 PF02796.15 CEP13773.1 - 6.5e-05 22.9 0.4 0.99 9.5 0.2 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 CEP13773.1 - 0.00022 20.8 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_32 PF13565.6 CEP13773.1 - 0.0032 18.0 0.0 0.0058 17.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain MerR_1 PF13411.6 CEP13773.1 - 0.016 15.3 0.1 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF4811 PF16069.5 CEP13773.1 - 0.025 14.5 1.2 0.035 14.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) HTH_23 PF13384.6 CEP13773.1 - 0.042 13.6 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.7 CEP13773.1 - 0.045 13.9 0.2 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP13773.1 - 0.1 12.9 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Transposase Chromo PF00385.24 CEP13774.1 - 1.9e-08 34.1 0.3 3e-08 33.4 0.3 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C97 PF05903.14 CEP13775.1 - 5.6e-43 146.4 0.0 1.2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 CEP13775.1 - 5e-38 130.9 8.2 5e-38 130.9 8.2 1.6 2 0 0 2 2 2 1 PUL domain Thioredoxin PF00085.20 CEP13775.1 - 1.1e-11 44.7 0.1 2.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEP13775.1 - 0.00033 21.1 0.3 0.0024 18.3 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CEP13775.1 - 0.00096 19.1 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP13775.1 - 0.0019 17.9 0.1 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CEP13775.1 - 0.0064 16.6 0.1 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CEP13775.1 - 0.0096 16.2 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Med2 PF11214.8 CEP13775.1 - 0.057 13.6 0.4 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 2 Thioredoxin_4 PF13462.6 CEP13775.1 - 0.29 11.3 1.5 17 5.5 0.2 2.8 2 1 1 3 3 3 0 Thioredoxin DUF775 PF05603.12 CEP13776.1 - 2.8e-53 180.4 0.2 4.5e-53 179.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) 2OG-FeII_Oxy_2 PF13532.6 CEP13776.1 - 2.2e-34 119.4 0.0 3.9e-33 115.3 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Yip1 PF04893.17 CEP13777.1 - 4.5e-08 33.0 16.1 8.4e-08 32.1 16.1 1.5 1 1 0 1 1 1 1 Yip1 domain Peptidase_M16_M PF16187.5 CEP13778.1 - 8.5e-106 353.3 1.9 1.7e-105 352.3 1.9 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CEP13778.1 - 5.7e-42 143.2 0.3 6.5e-41 139.8 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CEP13778.1 - 7.8e-34 117.3 0.3 4.4e-20 72.5 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Tet_JBP PF12851.7 CEP13778.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DDE_3 PF13358.6 CEP13779.1 - 2.6e-26 92.1 0.0 1.2e-17 64.0 0.0 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP13779.1 - 0.046 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 CEP13779.1 - 0.11 12.7 0.1 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CEP13779.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Malic_M PF03949.15 CEP13780.1 - 7e-94 313.9 0.0 9.2e-94 313.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEP13780.1 - 3.9e-72 241.9 0.0 8.4e-72 240.8 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain SelB-wing_2 PF09106.11 CEP13780.1 - 0.038 14.2 0.0 36 4.7 0.0 3.6 3 0 0 3 3 3 0 Elongation factor SelB, winged helix SDH_alpha PF03313.15 CEP13781.1 - 0.024 14.3 0.6 0.034 13.8 0.6 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain Recep_L_domain PF01030.24 CEP13782.1 - 0.029 14.5 2.9 0.18 11.9 0.6 3.1 3 1 0 3 3 3 0 Receptor L domain DUF3568 PF12092.8 CEP13782.1 - 0.093 12.8 2.9 0.18 11.9 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Endotoxin_N PF03945.14 CEP13782.1 - 0.16 11.7 5.7 0.098 12.4 0.8 2.3 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Sugar_tr PF00083.24 CEP13783.1 - 7.8e-37 127.2 33.4 1.2e-22 80.4 10.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP13783.1 - 1.8e-17 63.3 60.6 9.5e-16 57.7 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LRR_6 PF13516.6 CEP13784.1 - 0.0028 17.6 7.0 0.71 10.1 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CEP13784.1 - 0.042 14.3 9.9 0.16 12.4 2.5 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ribosomal_S9 PF00380.19 CEP13785.1 - 1.2e-31 109.8 0.1 1.3e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.20 CEP13786.1 - 2.9e-105 350.7 5.7 3.4e-105 350.5 5.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Syja_N PF02383.18 CEP13787.1 - 8.7e-83 278.3 0.2 2.4e-82 276.8 0.2 1.8 1 0 0 1 1 1 1 SacI homology domain Crystall PF00030.19 CEP13787.1 - 0.035 14.3 0.6 3.4 7.9 0.1 2.8 2 0 0 2 2 2 0 Beta/Gamma crystallin Syja_N PF02383.18 CEP13788.1 - 2.5e-84 283.4 1.1 3.2e-84 283.0 1.1 1.1 1 0 0 1 1 1 1 SacI homology domain LRR_4 PF12799.7 CEP13789.1 - 4.7e-10 39.6 15.4 4.7e-05 23.7 2.1 3.9 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CEP13789.1 - 6.8e-08 32.2 0.5 6.8e-08 32.2 0.5 1.9 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 CEP13789.1 - 1e-06 28.4 15.0 0.00015 21.5 6.2 3.4 1 1 2 3 3 3 3 Leucine rich repeat Ubiquitin_2 PF14560.6 CEP13789.1 - 1.1e-05 25.8 0.5 3.6e-05 24.1 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 CEP13789.1 - 0.069 12.9 0.2 0.069 12.9 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin family LRR_6 PF13516.6 CEP13789.1 - 0.43 10.8 11.3 2.3 8.5 0.3 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_trans_1_3 PF13528.6 CEP13790.1 - 1.8e-05 24.2 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 1 tRNA-synt_2b PF00587.25 CEP13791.1 - 6.6e-28 97.9 0.0 1.2e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CEP13791.1 - 1.4e-10 41.3 3.8 1.4e-10 41.3 3.8 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NSP16 PF06460.12 CEP13791.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NSP16 DUF4310 PF14187.6 CEP13791.1 - 0.18 11.5 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) CAP_GLY PF01302.25 CEP13792.1 - 1.4e-19 69.8 0.4 2.5e-19 69.0 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain FA_desaturase PF00487.24 CEP13793.1 - 2.4e-26 93.1 20.8 3.8e-26 92.5 20.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CEP13793.1 - 1.8e-07 31.4 0.0 4.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Eaf7 PF07904.13 CEP13794.1 - 1.4e-22 80.0 0.2 3.1e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 PPR_2 PF13041.6 CEP13795.1 - 2.3e-23 82.1 7.1 1.2e-05 25.4 0.0 10.6 11 1 1 12 12 12 3 PPR repeat family PPR_3 PF13812.6 CEP13795.1 - 9.3e-16 57.7 0.4 2.8e-05 24.1 0.0 6.7 6 1 1 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.20 CEP13795.1 - 4.9e-13 48.4 7.9 0.07 13.4 0.0 10.0 11 0 0 11 11 11 2 PPR repeat PPR_1 PF12854.7 CEP13795.1 - 2.2e-08 33.6 0.6 0.00015 21.4 0.0 5.5 7 0 0 7 7 7 1 PPR repeat TPR_14 PF13428.6 CEP13795.1 - 8.1e-05 23.1 0.3 36 5.5 0.0 5.9 5 2 2 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP13795.1 - 0.0001 22.4 0.0 0.013 15.7 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEP13795.1 - 0.0059 17.1 0.0 4.1 8.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 CEP13795.1 - 0.011 16.2 0.0 7 7.1 0.1 3.6 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_11 PF13414.6 CEP13795.1 - 0.024 14.3 0.7 1.3 8.7 0.0 3.7 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.17 CEP13795.1 - 0.092 12.9 0.2 38 4.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Hydrolase_6 PF13344.6 CEP13796.1 - 1.7e-24 85.8 0.0 7.7e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP13796.1 - 3.3e-21 75.1 0.0 9.8e-21 73.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP13796.1 - 7.5e-05 23.1 0.0 0.95 9.7 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP13796.1 - 0.0038 17.3 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Kinesin PF00225.23 CEP13797.1 - 1.2e-103 346.6 0.1 1.2e-103 346.6 0.1 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP13797.1 - 2.6e-19 69.6 15.3 1.6e-16 60.6 0.0 5.0 3 2 2 5 5 5 2 Microtubule binding PKcGMP_CC PF16808.5 CEP13797.1 - 1.2 9.0 33.3 2.6 8.0 2.7 6.9 7 0 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OTU PF02338.19 CEP13799.1 - 5.5e-11 43.1 1.2 1.4e-10 41.8 1.2 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 CEP13799.1 - 0.087 12.6 0.2 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 CUE domain ORC_WH_C PF18137.1 CEP13799.1 - 4.4 7.4 9.8 10 6.2 5.2 2.7 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DDE_3 PF13358.6 CEP13802.1 - 1e-07 31.8 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BEX PF04538.12 CEP13803.1 - 0.015 15.9 2.7 0.018 15.6 2.7 1.1 1 0 0 1 1 1 0 Brain expressed X-linked like family DDE_3 PF13358.6 CEP13804.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Adhesin_E PF16747.5 CEP13805.1 - 0.02 15.0 0.1 0.25 11.4 0.0 2.6 3 0 0 3 3 3 0 Surface-adhesin protein E PHD_3 PF13922.6 CEP13805.1 - 1.5 9.2 5.4 1 9.8 1.4 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Methyltransf_25 PF13649.6 CEP13806.1 - 2.2e-08 34.7 0.0 4.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP13806.1 - 3e-08 34.2 0.0 5.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP13806.1 - 5.7e-07 29.5 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP13806.1 - 0.00081 19.2 0.1 0.0097 15.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP13806.1 - 0.0023 18.7 0.0 0.0071 17.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 CEP13806.1 - 0.028 13.0 0.4 0.066 11.7 0.2 1.6 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 CEP13806.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Cyt-b5 PF00173.28 CEP13807.1 - 1.7e-22 79.3 0.0 1.9e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 CEP13807.1 - 0.015 15.4 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Myb_DNA-binding PF00249.31 CEP13808.1 - 9.1e-05 22.6 0.1 0.00022 21.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP13808.1 - 0.0016 18.6 0.1 0.0016 18.6 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Fer4_10 PF13237.6 CEP13808.1 - 0.086 13.0 2.5 0.21 11.7 2.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain NifW PF03206.14 CEP13808.1 - 0.25 11.9 13.1 2.8 8.5 10.6 2.7 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Aa_trans PF01490.18 CEP13809.1 - 2.8e-76 256.9 19.3 3.4e-76 256.6 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEP13809.1 - 2.4e-10 40.0 13.5 2.4e-10 40.0 13.5 1.7 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Adeno_E3_14_5 PF04834.12 CEP13809.1 - 0.004 17.7 2.8 0.0091 16.5 0.3 2.7 2 1 0 2 2 2 1 Early E3 14.5 kDa protein DAGK_prokar PF01219.19 CEP13809.1 - 2.2 8.2 5.8 0.36 10.7 1.0 2.2 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase DAHP_synth_1 PF00793.20 CEP13811.1 - 3.5e-100 334.4 0.0 4e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PHP PF02811.19 CEP13812.1 - 3.2e-16 60.1 0.2 4.6e-16 59.6 0.2 1.2 1 0 0 1 1 1 1 PHP domain Glucosamine_iso PF01182.20 CEP13813.1 - 2e-11 44.2 0.0 1.3e-07 31.8 0.0 2.3 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Asn_synthase PF00733.21 CEP13814.1 - 6.3e-70 236.6 0.0 8.2e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CEP13814.1 - 2.9e-41 140.2 0.0 4.8e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEP13814.1 - 6.3e-34 117.1 0.0 1.2e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain adh_short_C2 PF13561.6 CEP13815.1 - 3.2e-05 23.6 0.0 4.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP13815.1 - 0.0004 19.9 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DEAD PF00270.29 CEP13816.1 - 4.2e-41 140.6 0.0 1.9e-40 138.5 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP13816.1 - 5.7e-29 100.7 0.0 1.5e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CEP13816.1 - 0.013 14.3 0.0 10 4.8 0.0 3.1 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 CEP13816.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrbI_Ftype PF09677.10 CEP13816.1 - 0.24 11.7 0.4 4.1 7.8 0.0 2.6 2 1 1 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) Tyr_Deacylase PF02580.16 CEP13817.1 - 2.4e-54 183.8 0.1 2.7e-54 183.6 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase zf-CCHC PF00098.23 CEP13818.1 - 0.003 17.6 13.7 0.0034 17.4 1.2 2.3 2 0 0 2 2 2 2 Zinc knuckle MMM1 PF10296.9 CEP13819.1 - 3e-05 23.2 0.0 3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 MRG PF05712.13 CEP13820.1 - 7.4e-56 188.6 4.8 1.1e-55 188.0 4.8 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CEP13820.1 - 4.1e-13 49.0 1.0 8.6e-13 48.0 1.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 CEP13820.1 - 0.021 14.7 3.8 0.074 13.0 3.8 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ADH_zinc_N PF00107.26 CEP13821.1 - 3.2e-26 91.8 0.9 5.3e-26 91.1 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP13821.1 - 1.9e-18 67.8 0.0 3.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP13821.1 - 2.8e-09 36.8 0.0 3.5e-08 33.3 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S8e PF01201.22 CEP13821.1 - 0.0039 17.4 0.2 0.0091 16.2 0.2 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Arg_repressor_C PF02863.18 CEP13821.1 - 0.022 14.6 3.4 2.2 8.2 0.5 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Cas9_PI2 PF18070.1 CEP13821.1 - 2.9 8.7 5.7 3.1 8.6 0.5 3.0 3 1 1 4 4 4 0 CRISPR-Cas9 PI domain Pribosyltran PF00156.27 CEP13822.1 - 3e-14 52.9 0.1 8.3e-14 51.4 0.1 1.7 1 1 1 2 2 2 1 Phosphoribosyl transferase domain PA PF02225.22 CEP13822.1 - 0.039 14.0 0.5 0.077 13.0 0.5 1.5 1 0 0 1 1 1 0 PA domain PRTase_2 PF15609.6 CEP13822.1 - 0.19 11.2 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase CDP-OH_P_transf PF01066.21 CEP13823.1 - 2.6e-13 50.5 0.2 2.6e-13 50.5 0.2 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase COPI_assoc PF08507.10 CEP13823.1 - 3.8 7.6 9.9 0.82 9.7 5.4 2.3 2 1 0 2 2 2 0 COPI associated protein HSF_DNA-bind PF00447.17 CEP13824.1 - 1.2e-32 112.4 1.5 1.2e-32 112.4 1.5 3.0 3 0 0 3 3 3 1 HSF-type DNA-binding Acyltransferase PF01553.21 CEP13825.1 - 7.1e-21 74.2 0.0 1.4e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PX PF00787.24 CEP13827.1 - 2e-10 40.6 1.3 4.6e-10 39.5 1.3 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 CEP13827.1 - 0.0051 16.7 0.0 0.019 14.9 0.0 2.1 1 0 0 1 1 1 1 PB1 domain Dynactin_p62 PF05502.13 CEP13828.1 - 9.9e-93 311.5 20.0 1.2e-46 159.5 14.9 2.1 1 1 1 2 2 2 2 Dynactin p62 family zf_UBZ PF18439.1 CEP13828.1 - 4.7 6.9 7.5 51 3.6 0.3 3.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SET PF00856.28 CEP13829.1 - 7e-11 42.8 0.2 7.1e-10 39.5 0.1 2.5 2 1 0 2 2 2 1 SET domain DUF4484 PF14831.6 CEP13829.1 - 0.18 11.8 5.9 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF4746 PF15928.5 CEP13829.1 - 1.5 8.2 9.2 0.14 11.5 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PBP1_TM PF14812.6 CEP13829.1 - 3.4 8.1 19.9 0.85 10.0 6.7 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-piccolo PF05715.13 CEP13829.1 - 6.1 7.1 8.6 17 5.6 8.6 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger CAF1 PF04857.20 CEP13830.1 - 1.5e-20 73.7 0.5 3.1e-09 36.5 0.0 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease Ldh_1_C PF02866.18 CEP13831.1 - 7.7e-49 165.8 0.1 1.4e-48 165.0 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CEP13831.1 - 5.6e-45 152.9 0.1 9e-45 152.2 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CEP13831.1 - 5.6e-05 22.3 0.0 0.0002 20.5 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CEP13831.1 - 0.0019 18.3 0.3 0.0065 16.6 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Glyco_transf_20 PF00982.21 CEP13832.1 - 6.8e-155 516.4 0.0 1e-154 515.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP13832.1 - 1.6e-54 184.5 0.0 2.4e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEP13832.1 - 8.4e-05 22.4 0.2 0.34 10.6 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Polyhedrin PF00738.18 CEP13832.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Polyhedrin Pkinase PF00069.25 CEP13833.1 - 2.1e-67 227.2 0.6 1.3e-61 208.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13833.1 - 9.4e-40 136.5 0.1 1.2e-38 132.9 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13833.1 - 1.1e-06 28.3 0.0 2.8e-06 26.9 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP13833.1 - 2.2e-05 23.9 1.7 5.9e-05 22.5 1.7 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP13833.1 - 4.2e-05 23.6 0.2 0.00066 19.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEP13833.1 - 0.001 18.7 0.9 0.0024 17.5 0.9 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CEP13833.1 - 0.019 14.0 0.1 0.019 14.0 0.1 2.6 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP13833.1 - 0.021 13.6 1.0 0.047 12.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CEP13833.1 - 0.091 12.3 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 CEP13833.1 - 0.16 11.5 1.2 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CMD PF02627.20 CEP13834.1 - 0.0004 20.4 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Med14 PF08638.11 CEP13834.1 - 0.046 13.1 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 RPE65 PF03055.15 CEP13835.1 - 3e-85 287.2 0.0 3.8e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Rhomboid PF01694.22 CEP13836.1 - 4.2e-05 23.6 0.2 0.00018 21.6 0.0 2.1 2 0 0 2 2 2 1 Rhomboid family KH_1 PF00013.29 CEP13837.1 - 2e-43 146.0 9.4 4.8e-17 61.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEP13837.1 - 2.1e-11 43.5 5.1 0.016 15.0 0.0 3.7 3 1 1 4 4 4 3 KH domain KH_4 PF13083.6 CEP13837.1 - 1.6e-09 37.5 1.1 0.07 13.0 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CEP13837.1 - 0.00019 21.5 5.9 0.042 13.9 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain ApoO PF09769.9 CEP13837.1 - 0.061 13.3 0.3 0.29 11.1 0.1 2.1 2 1 0 2 2 2 0 Apolipoprotein O Codanin-1_C PF15296.6 CEP13837.1 - 0.41 10.7 6.4 1.4 9.0 6.4 1.9 1 0 0 1 1 1 0 Codanin-1 C-terminus SUIM_assoc PF16619.5 CEP13837.1 - 3.9 7.6 19.0 13 6.0 19.0 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CPBP PF02517.16 CEP13839.1 - 2.2e-17 63.2 11.4 5.6e-17 61.9 11.4 1.9 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Rad10 PF03834.14 CEP13840.1 - 2.4e-44 150.0 0.0 4.4e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CEP13840.1 - 3.8e-08 33.8 0.0 8.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CEP13840.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 CEP13841.1 - 1.7e-62 211.2 0.0 2.9e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13841.1 - 3.3e-31 108.5 0.0 5.5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP13841.1 - 1.1e-06 29.2 0.0 4.5e-06 27.3 0.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CEP13841.1 - 3.8e-05 23.1 0.0 0.00048 19.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PX PF00787.24 CEP13841.1 - 0.00032 20.7 0.8 0.00079 19.4 0.8 1.7 1 0 0 1 1 1 1 PX domain FTA2 PF13095.6 CEP13841.1 - 0.0012 18.5 0.0 0.31 10.6 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP13841.1 - 0.0061 16.5 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family IMP2_N PF18590.1 CEP13841.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Peptidase_S8 PF00082.22 CEP13842.1 - 1.2e-34 119.9 5.8 2.6e-34 118.9 5.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEP13842.1 - 1.3e-14 54.6 0.4 2.4e-14 53.8 0.4 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ank_2 PF12796.7 CEP13843.1 - 3.3e-27 94.9 0.4 7.5e-09 36.1 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP13843.1 - 9.3e-20 70.7 5.7 2.3e-07 31.2 0.1 6.0 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP13843.1 - 1.3e-12 47.7 0.4 0.00027 21.2 0.0 5.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP13843.1 - 3.4e-12 45.4 4.3 0.00055 20.2 0.1 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 CEP13843.1 - 1.2e-06 28.7 8.1 0.18 12.3 0.0 6.5 7 1 1 8 8 8 2 Ankyrin repeat DDE_3 PF13358.6 CEP13844.1 - 1.7e-20 73.3 0.0 2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Asparaginase_2 PF01112.18 CEP13845.1 - 2.7e-16 59.5 0.2 1.9e-11 43.5 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Asparaginase_2 PF01112.18 CEP13846.1 - 2.5e-22 79.3 0.1 2.8e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Asparaginase AMP-binding PF00501.28 CEP13847.1 - 3.3e-53 180.8 0.0 9.8e-27 93.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEP13847.1 - 9e-11 42.6 0.0 1.6e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asp PF00026.23 CEP13848.1 - 2.3e-58 198.1 5.6 9e-58 196.1 3.8 2.5 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP13848.1 - 3.9e-09 37.0 1.4 3.9e-09 37.0 1.4 4.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal zf-C2H2 PF00096.26 CEP13848.1 - 5.9e-06 26.5 19.1 0.0013 19.1 4.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEP13848.1 - 0.00059 20.1 1.0 0.0028 17.9 1.0 2.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CEP13848.1 - 0.0015 18.9 4.2 0.0015 18.9 4.2 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEP13848.1 - 0.0039 17.4 4.6 0.012 15.9 4.6 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 CEP13848.1 - 0.0076 17.0 3.7 0.0076 17.0 3.7 3.4 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP13848.1 - 0.026 14.5 3.6 0.073 13.1 3.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP13848.1 - 0.034 14.8 0.1 0.034 14.8 0.1 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain Asp_protease_2 PF13650.6 CEP13848.1 - 0.16 12.7 0.3 5 7.8 0.1 3.2 3 0 0 3 3 3 0 Aspartyl protease zf-met PF12874.7 CEP13848.1 - 0.42 11.1 3.5 0.74 10.3 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ILVD_EDD PF00920.21 CEP13849.1 - 1.2e-214 713.7 0.9 1.4e-214 713.5 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Ras PF00071.22 CEP13850.1 - 1.2e-18 67.2 0.0 1.3e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP13850.1 - 1.6e-12 47.7 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP13850.1 - 0.00085 18.8 0.0 0.00099 18.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family EMC3_TMCO1 PF01956.16 CEP13851.1 - 0.031 14.0 1.0 0.056 13.2 0.2 1.8 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 CEP13851.1 - 0.11 11.3 0.1 0.11 11.3 0.1 2.3 2 1 1 3 3 3 0 Presenilin MBOAT PF03062.19 CEP13852.1 - 6.8e-36 124.3 13.4 6.8e-36 124.3 13.4 2.1 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PsaL PF02605.15 CEP13852.1 - 0.084 12.5 0.1 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI SRF-TF PF00319.18 CEP13853.1 - 8.6e-17 60.4 0.4 2e-16 59.2 0.4 1.6 1 1 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Med3 PF11593.8 CEP13853.1 - 0.0002 20.7 9.7 0.00032 20.0 9.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.19 CEP13853.1 - 0.011 16.4 3.7 0.018 15.7 3.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PepSY_TM PF03929.16 CEP13853.1 - 0.066 12.9 0.5 0.099 12.3 0.5 1.3 1 0 0 1 1 1 0 PepSY-associated TM region TFIIA PF03153.13 CEP13853.1 - 0.09 12.8 9.6 0.091 12.7 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HbrB PF08539.11 CEP13854.1 - 1.7e-37 129.0 3.1 1.7e-36 125.7 0.3 3.3 2 1 0 2 2 2 1 HbrB-like Tropomyosin_1 PF12718.7 CEP13854.1 - 0.22 11.7 1.2 0.65 10.1 1.2 1.8 1 0 0 1 1 1 0 Tropomyosin like Zn_clus PF00172.18 CEP13854.1 - 0.79 9.9 5.8 1.6 8.9 5.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_3 PF13358.6 CEP13855.1 - 6e-19 68.2 0.1 4.9e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP13855.1 - 1.1e-06 28.7 0.1 2.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP13855.1 - 5.6e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 CEP13855.1 - 9e-05 22.2 0.3 0.00024 20.8 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP13855.1 - 0.0003 21.4 0.0 0.00056 20.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEP13855.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 CEP13855.1 - 0.0082 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF2089 PF09862.9 CEP13855.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Ndr PF03096.14 CEP13855.1 - 0.091 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Ndr family PAX PF00292.18 CEP13855.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Pkinase PF00069.25 CEP13857.1 - 1.8e-49 168.5 0.0 2.9e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13857.1 - 3.2e-41 141.3 0.0 5.2e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP13857.1 - 0.00063 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP13857.1 - 0.0039 17.2 0.2 0.64 9.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEP13857.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1206 PF06724.11 CEP13858.1 - 2.1e-17 63.0 23.2 3.3e-10 39.9 4.4 3.7 3 1 0 3 3 3 2 Domain of Unknown Function (DUF1206) DUF1385 PF07136.11 CEP13858.1 - 0.12 11.6 1.0 3.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DDE_3 PF13358.6 CEP13859.1 - 3.2e-20 72.4 0.1 5.8e-17 61.8 0.0 3.4 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_29 PF13551.6 CEP13859.1 - 0.00025 21.0 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 CEP13859.1 - 0.00032 20.4 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 CEP13859.1 - 0.00093 19.3 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 CEP13859.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.12 CEP13859.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1_2 PF13022.6 CEP13859.1 - 0.057 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LZ_Tnp_IS481 PF13011.6 CEP13859.1 - 0.071 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Fungal_trans PF04082.18 CEP13860.1 - 1.7e-35 122.4 0.8 5.9e-35 120.6 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Atg14 PF10186.9 CEP13861.1 - 2.3e-12 46.6 10.6 2.3e-12 46.6 10.6 2.6 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 CEP13861.1 - 1.1e-09 37.7 11.6 1.5e-08 34.0 5.6 2.8 3 1 0 3 3 3 2 Vacuolar protein sorting 38 DUF3552 PF12072.8 CEP13861.1 - 0.0053 16.2 6.2 0.01 15.3 6.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Homoserine_dh PF00742.19 CEP13862.1 - 3.1e-47 160.7 0.0 4.6e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CEP13862.1 - 1.3e-16 61.3 0.0 2.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CEP13862.1 - 0.028 14.8 0.1 0.091 13.2 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CEP13862.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 CEP13862.1 - 0.13 12.8 0.1 0.38 11.4 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ras PF00071.22 CEP13863.1 - 8.6e-55 184.8 0.0 1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP13863.1 - 1.8e-21 76.6 0.0 3.5e-21 75.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP13863.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEP13863.1 - 0.0024 17.8 0.0 2 8.3 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CEP13863.1 - 0.0055 15.9 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CEP13863.1 - 0.007 16.4 0.0 0.0093 16.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP13863.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEP13863.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CEP13863.1 - 0.044 14.3 0.0 0.083 13.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CEP13863.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 CEP13864.1 - 1.8e-56 187.8 0.3 3.7e-19 68.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP13864.1 - 5.5e-12 45.4 0.0 9.9e-06 25.2 0.0 3.1 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP13864.1 - 6.2e-09 35.6 0.0 0.00058 19.7 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CEP13864.1 - 2.3e-06 27.7 0.1 0.15 12.2 0.0 4.0 2 2 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CEP13864.1 - 0.0003 20.7 0.0 0.36 10.8 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CEP13864.1 - 0.00043 20.5 0.2 1.7 8.8 0.0 3.2 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 CEP13864.1 - 0.011 15.4 0.0 5.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 CEP13864.1 - 0.11 12.6 0.3 1.7 8.8 0.0 2.8 4 0 0 4 4 4 0 Limkain b1 Big_3_3 PF13750.6 CEP13865.1 - 0.036 13.7 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) GATA PF00320.27 CEP13867.1 - 1.6e-29 101.2 15.0 1.8e-15 56.3 3.3 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CEP13867.1 - 2.3e-12 46.5 1.2 1.1e-11 44.3 1.6 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DZR PF12773.7 CEP13867.1 - 0.00093 19.2 4.0 0.0088 16.1 3.2 2.9 1 1 2 3 3 3 2 Double zinc ribbon Zn-ribbon_8 PF09723.10 CEP13867.1 - 0.0017 18.4 0.9 2.9 8.1 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEP13867.1 - 0.0022 17.4 4.8 0.034 13.7 0.3 2.8 2 0 0 2 2 2 1 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 CEP13867.1 - 0.63 9.9 3.9 6.6 6.6 0.7 2.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CEP13867.1 - 2.2 8.5 7.8 3 8.1 0.3 2.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 CEP13867.1 - 3.2 7.6 8.6 8.5 6.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CEP13867.1 - 4.6 8.1 6.3 16 6.3 2.0 3.2 1 1 2 3 3 3 0 zinc-ribbon family DUF5538 PF17692.1 CEP13867.1 - 6.5 6.8 10.7 0.28 11.2 4.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5538) KDZ PF18758.1 CEP13868.1 - 9.4e-16 58.1 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2406 PF10295.9 CEP13868.1 - 0.067 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) CxC2 PF18803.1 CEP13869.1 - 5.7e-06 26.5 1.3 9.7e-06 25.7 1.3 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 CEP13869.1 - 0.0021 17.7 0.1 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CEP13869.1 - 0.098 12.8 0.9 0.2 11.8 0.9 1.5 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Dam PF05869.11 CEP13870.1 - 0.00016 21.3 0.3 0.00028 20.5 0.3 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) PRK PF00485.18 CEP13871.1 - 1.1e-28 100.3 0.0 1.4e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 CEP13871.1 - 0.0077 16.0 2.9 0.58 9.8 0.1 2.5 1 1 1 2 2 2 2 Cytidylate kinase AAA_18 PF13238.6 CEP13871.1 - 0.053 14.1 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CEP13871.1 - 0.059 12.8 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein RRM_1 PF00076.22 CEP13872.1 - 6.5e-19 67.5 0.0 1.6e-13 50.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CEP13872.1 - 0.025 14.6 20.2 0.038 14.0 20.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_7 PF16367.5 CEP13872.1 - 0.064 13.4 0.0 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif Anp1 PF03452.14 CEP13872.1 - 0.66 9.3 6.5 1.1 8.6 6.5 1.2 1 0 0 1 1 1 0 Anp1 Pex14_N PF04695.13 CEP13872.1 - 4.5 7.9 20.7 1.7 9.3 8.9 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNF2_N PF00176.23 CEP13873.1 - 2.6e-65 220.4 0.5 5.4e-65 219.4 0.5 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP13873.1 - 1.6e-17 63.9 0.0 6e-17 62.0 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CEP13873.1 - 8.2e-09 35.2 4.9 1.7e-08 34.1 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP13873.1 - 1.7e-08 34.2 7.7 3.6e-08 33.1 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP13873.1 - 1.7e-08 34.6 6.3 5.1e-08 33.1 6.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP13873.1 - 2.3e-07 30.6 6.8 2.3e-07 30.6 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP13873.1 - 7.6e-07 28.9 6.1 3.3e-06 26.8 6.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEP13873.1 - 1.1e-06 28.5 6.5 4.2e-06 26.7 6.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP13873.1 - 1.4e-05 25.0 6.1 2.6e-05 24.1 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEP13873.1 - 1.8e-05 24.8 11.3 3.5e-05 23.8 6.8 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 CEP13873.1 - 5.6e-05 23.2 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEP13873.1 - 0.00029 20.6 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-ANAPC11 PF12861.7 CEP13873.1 - 0.008 16.2 1.8 0.016 15.2 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEP13873.1 - 0.059 13.2 5.5 0.15 11.9 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 CEP13873.1 - 0.088 12.6 2.1 0.25 11.2 2.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_IE-1 PF05290.11 CEP13873.1 - 0.11 12.4 0.4 0.23 11.4 0.4 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF4718 PF15842.5 CEP13873.1 - 0.14 12.0 1.9 0.38 10.5 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) zf-RING_6 PF14835.6 CEP13873.1 - 0.21 11.5 2.8 0.46 10.4 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CEP13873.1 - 0.24 11.7 3.2 0.65 10.3 3.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 CEP13873.1 - 0.35 10.9 3.6 1 9.4 3.6 1.8 1 1 0 1 1 1 0 zinc-ribbons DUF3446 PF11928.8 CEP13873.1 - 0.36 11.2 15.1 3.4 8.0 0.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF1644 PF07800.12 CEP13873.1 - 2.8 8.0 5.3 4.8 7.2 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) SR-25 PF10500.9 CEP13873.1 - 9.4 5.8 11.5 0.32 10.6 4.9 1.9 3 0 0 3 3 1 0 Nuclear RNA-splicing-associated protein zf-PARP PF00645.18 CEP13874.1 - 5.1e-13 49.7 0.1 5.1e-13 49.7 0.1 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Beta-lactamase PF00144.24 CEP13875.1 - 6.1e-40 137.5 0.6 5.2e-39 134.4 0.6 1.9 1 1 0 1 1 1 1 Beta-lactamase Baculo_PEP_C PF04513.12 CEP13876.1 - 0.0009 19.3 1.2 0.001 19.1 1.2 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LTXXQ PF07813.12 CEP13876.1 - 0.087 13.6 0.0 0.1 13.3 0.0 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein Helicase_C_2 PF13307.6 CEP13877.1 - 4.9e-54 183.1 0.0 1.9e-53 181.1 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CEP13877.1 - 1.5e-51 174.5 0.1 2.7e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CEP13877.1 - 8.6e-05 22.6 0.2 0.37 10.8 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CEP13877.1 - 0.013 15.2 1.3 2 8.2 0.2 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase MRPL52 PF18699.1 CEP13877.1 - 2.7 8.2 6.6 0.83 9.9 0.8 2.8 2 0 0 2 2 2 0 Mitoribosomal protein mL52 E1-E2_ATPase PF00122.20 CEP13878.1 - 1.4e-24 86.6 0.0 5.3e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEP13878.1 - 8.3e-10 39.3 1.1 0.00057 20.2 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP13878.1 - 0.00043 19.9 0.0 0.00043 19.9 0.0 2.8 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP13878.1 - 0.0035 17.4 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP13878.1 - 0.018 14.8 0.1 0.21 11.3 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Adeno_PV PF03910.13 CEP13880.1 - 0.033 12.9 0.3 0.071 11.8 0.3 1.5 1 0 0 1 1 1 0 Adenovirus minor core protein PV Glyco_hydro_16 PF00722.21 CEP13881.1 - 2.2e-19 69.6 1.2 3.7e-19 68.9 1.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2854 PF11016.8 CEP13881.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DUF1080 PF06439.11 CEP13881.1 - 0.014 15.5 2.8 0.14 12.2 2.8 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) USP8_dimer PF08969.11 CEP13882.1 - 0.021 15.0 0.9 0.072 13.3 0.9 1.9 1 0 0 1 1 1 0 USP8 dimerisation domain Ribosomal_L44 PF00935.19 CEP13883.1 - 5.2e-38 129.4 10.1 8e-38 128.8 10.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ldh_1_N PF00056.23 CEP13884.1 - 1.7e-32 112.4 1.2 2.6e-32 111.8 0.7 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CEP13884.1 - 8.4e-21 74.6 0.1 1.8e-20 73.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 CEP13884.1 - 0.0071 15.9 0.7 0.019 14.5 0.7 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CEP13884.1 - 0.019 14.6 0.5 0.069 12.8 0.5 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CEP13884.1 - 0.021 14.7 0.1 0.044 13.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEP13884.1 - 0.038 13.3 0.5 0.057 12.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CEP13884.1 - 0.066 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP13884.1 - 0.067 12.8 1.8 0.13 11.8 0.6 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP13884.1 - 0.069 12.4 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 CEP13884.1 - 0.092 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 CEP13884.1 - 0.097 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CEP13884.1 - 0.1 13.2 0.5 0.33 11.6 0.5 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 CEP13884.1 - 0.14 12.7 0.1 0.34 11.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase S6OS1 PF15676.5 CEP13885.1 - 0.041 12.4 1.6 0.053 12.0 1.6 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Macoilin PF09726.9 CEP13885.1 - 0.08 11.5 1.5 0.083 11.4 1.5 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 CEP13885.1 - 2.9 7.7 9.6 3.8 7.3 9.6 1.1 1 0 0 1 1 1 0 SPX domain tRNA-synt_1 PF00133.22 CEP13886.1 - 1.7e-62 211.5 0.0 2.6e-22 78.9 0.6 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CEP13886.1 - 4.8e-56 189.2 0.0 7.3e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CEP13886.1 - 4e-30 104.9 1.7 1.3e-20 73.5 0.0 4.5 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEP13886.1 - 3.9e-19 69.1 0.0 8.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CEP13886.1 - 0.026 13.9 0.0 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GCN5L1 PF06320.13 CEP13886.1 - 0.03 14.4 1.3 0.12 12.5 0.6 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) MoCF_biosynth PF00994.24 CEP13887.1 - 1.6e-61 206.1 0.5 3.9e-31 107.6 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CEP13887.1 - 3.3e-37 127.7 0.8 5.8e-37 126.9 0.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CEP13887.1 - 2.6e-13 49.9 0.0 8.3e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Radical_SAM PF04055.21 CEP13887.1 - 0.053 13.9 0.0 5 7.5 0.0 2.7 3 0 0 3 3 3 0 Radical SAM superfamily Abhydrolase_2 PF02230.16 CEP13887.1 - 0.068 13.0 0.4 0.73 9.6 0.1 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Polyketide_cyc2 PF10604.9 CEP13888.1 - 0.01 16.1 0.1 0.016 15.5 0.1 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Methyltr_RsmB-F PF01189.17 CEP13889.1 - 7.5e-30 104.1 0.1 6.2e-20 71.7 0.0 2.4 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CEP13889.1 - 0.00013 22.6 0.1 0.0014 19.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP13889.1 - 0.007 16.2 0.1 0.14 12.0 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CEP13889.1 - 0.011 15.9 0.2 0.042 14.0 0.2 2.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CEP13889.1 - 0.05 13.4 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TSNR_N PF04705.12 CEP13889.1 - 0.18 11.9 0.1 0.53 10.4 0.1 1.7 1 1 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Acetyltransf_10 PF13673.7 CEP13890.1 - 1.3e-13 51.0 0.0 2e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP13890.1 - 7.3e-10 39.1 0.1 8.9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP13890.1 - 9.1e-09 35.6 0.1 1.2e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 CEP13890.1 - 0.0025 18.5 0.2 0.013 16.2 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP13890.1 - 0.016 15.3 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEP13890.1 - 0.023 14.8 0.0 0.09 12.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP13890.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SHOCT PF09851.9 CEP13892.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain DUF4625 PF15418.6 CEP13893.1 - 0.019 15.2 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) SGBP_B_XBD PF18329.1 CEP13893.1 - 0.11 12.5 0.2 0.19 11.6 0.2 1.3 1 1 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain DUF3498 PF12004.8 CEP13893.1 - 0.14 11.3 1.1 0.15 11.2 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) SQS_PSY PF00494.19 CEP13894.1 - 1.5e-37 129.5 0.0 2.1e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase ArfGap PF01412.18 CEP13895.1 - 0.00014 21.9 0.4 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf LNP1 PF15419.6 CEP13895.1 - 0.04 14.2 0.0 0.045 14.0 0.0 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 AAA PF00004.29 CEP13896.1 - 3.7e-18 66.2 0.0 8.5e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEP13896.1 - 1.3e-15 57.6 0.2 2.1e-10 40.6 0.0 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CEP13896.1 - 2.9e-15 56.4 1.5 5.7e-15 55.5 1.5 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_11 PF13086.6 CEP13896.1 - 2.5e-06 27.5 0.2 7.5e-06 25.9 0.0 1.8 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 CEP13896.1 - 3.4e-05 24.1 0.2 0.0035 17.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CEP13896.1 - 8.7e-05 22.0 0.0 0.023 14.1 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CEP13896.1 - 9.3e-05 22.9 0.0 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP13896.1 - 0.00011 22.0 0.0 0.00048 19.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEP13896.1 - 0.00014 21.9 0.0 0.00055 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEP13896.1 - 0.00028 20.9 0.1 0.00088 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CEP13896.1 - 0.00034 20.6 0.0 0.0012 18.9 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CEP13896.1 - 0.0014 19.0 0.3 0.034 14.5 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CEP13896.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP13896.1 - 0.0016 18.2 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP13896.1 - 0.0022 18.4 0.1 0.01 16.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEP13896.1 - 0.0057 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CEP13896.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 CEP13896.1 - 0.014 15.7 0.0 0.049 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain DNA_pol3_delta PF06144.13 CEP13896.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.18 CEP13896.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CEP13896.1 - 0.021 14.7 0.1 0.12 12.3 0.0 2.2 3 0 0 3 3 2 0 Rad17 P-loop domain DUF2075 PF09848.9 CEP13896.1 - 0.023 13.9 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 CEP13896.1 - 0.034 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEP13896.1 - 0.044 13.7 0.1 0.092 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 CEP13896.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CEP13896.1 - 0.064 13.8 0.1 0.13 12.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CEP13896.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain HMG-CoA_red PF00368.18 CEP13898.1 - 2.5e-143 477.5 6.7 2.5e-143 477.5 6.7 2.0 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 CEP13898.1 - 7.1e-17 61.7 3.6 1.8e-16 60.4 3.6 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEP13898.1 - 2.8e-08 32.4 9.0 5.3e-08 31.4 9.0 1.4 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 CEP13898.1 - 0.0032 17.3 0.1 0.0086 15.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif PHD PF00628.29 CEP13899.1 - 4.3e-17 61.8 24.8 1.1e-09 38.1 9.6 3.1 3 1 0 3 3 3 2 PHD-finger C1_1 PF00130.22 CEP13899.1 - 0.0091 15.9 16.8 0.058 13.3 1.9 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 CEP13899.1 - 0.016 15.4 15.6 1.2 9.4 0.6 2.9 2 1 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_M15_3 PF08291.11 CEP13899.1 - 0.054 13.6 0.6 0.26 11.4 0.1 2.4 2 0 0 2 2 2 0 Peptidase M15 PHD_2 PF13831.6 CEP13899.1 - 1.1 8.9 16.1 1.9 8.1 0.2 3.8 3 1 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.6 CEP13899.1 - 1.3 8.6 15.2 2 8.0 0.8 3.6 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain BRCT PF00533.26 CEP13900.1 - 3.8e-12 46.4 0.0 8.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEP13900.1 - 2.3e-06 27.9 0.0 5.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CEP13900.1 - 0.0063 16.8 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CEP13900.1 - 0.0068 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SPT16 PF08644.11 CEP13901.1 - 1.8e-54 184.0 3.8 2.6e-54 183.5 0.0 3.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CEP13901.1 - 2.1e-44 151.2 0.4 4.7e-44 150.0 0.4 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CEP13901.1 - 1.1e-31 110.2 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CEP13901.1 - 8.6e-16 58.1 0.0 2.5e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like ANAPC4_WD40 PF12894.7 CEP13902.1 - 0.0046 17.2 0.0 0.12 12.7 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DCB PF16213.5 CEP13903.1 - 0.066 12.9 0.3 0.094 12.4 0.3 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MRP-S33 PF08293.11 CEP13903.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Retrotrans_gag PF03732.17 CEP13905.1 - 0.0005 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein AlaDh_PNT_N PF05222.15 CEP13905.1 - 0.05 13.9 0.3 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain gag-asp_proteas PF13975.6 CEP13905.1 - 0.072 13.7 0.1 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease KH_1 PF00013.29 CEP13906.1 - 1e-48 163.0 5.8 8.4e-18 64.0 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CEP13906.1 - 1.3e-13 50.6 3.4 0.00072 19.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CEP13906.1 - 5e-10 39.1 5.0 0.00025 20.9 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CEP13906.1 - 0.00057 19.9 7.0 0.26 11.4 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain DUF3292 PF11696.8 CEP13906.1 - 0.19 10.1 0.4 0.26 9.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) BMC PF00936.19 CEP13906.1 - 0.31 11.0 3.9 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 BMC domain Reeler PF02014.16 CEP13907.1 - 0.0031 18.2 0.0 0.0046 17.7 0.0 1.3 1 0 0 1 1 1 1 Reeler domain Anophelin PF10731.9 CEP13907.1 - 1.1 9.1 0.1 1.1 9.1 0.1 2.4 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Fz PF01392.22 CEP13908.1 - 1.6e-07 31.9 1.0 3.7e-07 30.8 1.0 1.6 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 CEP13908.1 - 6.1e-06 25.7 13.0 1.1e-05 24.9 13.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) S4 PF01479.25 CEP13909.1 - 4.3e-12 45.5 1.2 4.3e-12 45.5 1.2 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CEP13909.1 - 0.00017 22.5 0.0 0.0003 21.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CEP13910.1 - 1.5e-48 162.8 3.9 1.5e-48 162.8 3.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e MA3 PF02847.17 CEP13911.1 - 7.4e-29 100.0 0.2 1.6e-28 99.0 0.2 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CEP13911.1 - 1.4e-11 44.4 1.1 3.2e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 MIF4G domain THOC2_N PF16134.5 CEP13912.1 - 9.7e-102 341.6 3.9 2e-101 340.6 3.9 1.5 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CEP13912.1 - 7e-77 258.6 5.3 2.6e-76 256.7 3.5 2.4 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CEP13912.1 - 9.1e-24 83.3 0.0 1.6e-22 79.3 0.0 2.9 3 0 0 3 3 3 1 Transcription- and export-related complex subunit Homeodomain PF00046.29 CEP13913.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain MMTV_SAg PF01054.17 CEP13913.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Helitron_like_N PF14214.6 CEP13915.1 - 6.7e-07 29.7 0.5 2.7e-06 27.7 0.5 2.3 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Lar_N PF09861.9 CEP13917.1 - 0.0016 17.7 0.0 0.0037 16.5 0.0 1.5 2 0 0 2 2 2 1 Lactate racemase N-terminal domain gag-asp_proteas PF13975.6 CEP13918.1 - 7.3e-05 23.3 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CEP13918.1 - 0.0021 18.1 1.2 0.0043 17.1 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 CEP13918.1 - 0.0087 16.7 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP13918.1 - 0.015 15.0 0.1 0.035 13.9 0.1 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease DASH_Ask1 PF08655.10 CEP13918.1 - 0.11 12.4 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Ask1 zf-CCHC_5 PF14787.6 CEP13918.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RT_RNaseH PF17917.1 CEP13919.1 - 1.3e-23 83.3 0.0 2.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13919.1 - 3.8e-20 71.8 0.1 6.5e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP13919.1 - 1.7e-09 37.5 0.3 0.00015 21.3 0.0 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP13920.1 - 9.2e-22 77.3 0.0 1.9e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13920.1 - 8.7e-20 70.6 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP13920.1 - 6.6e-08 32.5 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP13920.1 - 5e-05 23.4 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger PIF1 PF05970.14 CEP13922.1 - 1.7e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP13922.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP13922.1 - 3.7e-05 23.6 0.0 0.0041 16.9 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CEP13922.1 - 0.01 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CEP13922.1 - 0.011 16.0 0.0 0.093 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEP13922.1 - 0.03 14.6 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEP13922.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP13922.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CEP13922.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CEP13923.1 - 2.6e-16 59.7 0.1 2.8e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP13923.1 - 1.6e-10 41.0 0.0 1.9e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP13923.1 - 8e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP13923.1 - 0.0009 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP13923.1 - 0.001 19.3 0.1 0.0026 18.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP13923.1 - 0.0011 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 CEP13923.1 - 0.0013 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.6 CEP13923.1 - 0.0013 19.1 0.0 0.0035 17.8 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CEP13923.1 - 0.0014 19.1 0.0 0.0032 18.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 CEP13923.1 - 0.021 14.0 0.1 0.044 13.0 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CEP13923.1 - 0.033 14.1 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 CEP13923.1 - 0.06 12.5 0.3 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CEP13923.1 - 0.061 13.1 0.3 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.7 CEP13923.1 - 0.071 12.0 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 CEP13923.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_1 PF00078.27 CEP13924.1 - 0.00058 19.4 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP13925.1 - 9.1e-21 74.4 0.0 2e-20 73.3 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CBS PF00571.28 CEP13928.1 - 9.5e-18 64.4 0.5 0.00038 20.8 0.1 4.6 4 1 0 4 4 4 4 CBS domain HSM3_N PF18795.1 CEP13928.1 - 0.012 15.1 1.3 0.012 15.1 1.3 1.6 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, N terminal domain Chitin_synth_1 PF01644.17 CEP13929.1 - 7.5e-72 240.6 0.0 1.3e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase DUF21 PF01595.20 CEP13929.1 - 9.5e-35 119.9 0.5 9.2e-34 116.7 0.7 2.3 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Chitin_synth_1N PF08407.11 CEP13929.1 - 3.6e-27 94.1 0.3 1e-26 92.7 0.3 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEP13929.1 - 4e-24 85.1 1.1 6.4e-24 84.5 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase CBS PF00571.28 CEP13929.1 - 1.6e-06 28.4 0.0 0.084 13.3 0.0 2.8 2 0 0 2 2 2 2 CBS domain Glyco_trans_2_3 PF13632.6 CEP13929.1 - 1.7e-05 24.8 0.1 1.7e-05 24.8 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP13929.1 - 0.0037 17.2 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ribosomal_S27e PF01667.17 CEP13930.1 - 2.1e-30 104.2 3.6 2.5e-30 103.9 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CEP13930.1 - 0.00055 19.4 3.1 0.00083 18.8 3.1 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 CEP13930.1 - 0.02 15.1 0.7 0.029 14.6 0.7 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 CEP13930.1 - 0.022 14.7 2.1 0.035 14.0 2.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC5 PF06221.13 CEP13930.1 - 0.031 14.3 2.5 0.031 14.3 2.5 1.7 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.6 CEP13930.1 - 0.06 13.3 1.9 2 8.4 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain DDE_3 PF13358.6 CEP13931.1 - 5.6e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Terminase_5 PF06056.12 CEP13931.1 - 0.0059 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 CEP13931.1 - 0.029 14.2 0.9 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 CEP13931.1 - 0.042 14.5 0.5 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEP13931.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase PHO4 PF01384.20 CEP13932.1 - 6.4e-118 393.6 21.4 7.7e-118 393.4 21.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF5434 PF17502.2 CEP13932.1 - 0.24 11.4 0.4 0.38 10.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5434) Pkinase PF00069.25 CEP13934.1 - 3.3e-21 75.8 0.0 4.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP13934.1 - 1.4e-08 34.3 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP13934.1 - 1e-07 31.1 1.1 1.8e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF3402 PF11882.8 CEP13935.1 - 9.4e-91 305.2 14.8 9.8e-54 183.2 5.2 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CEP13935.1 - 9.7e-26 90.6 9.9 5.3e-22 78.3 0.6 2.9 1 1 1 2 2 2 2 N1221-like protein CAF1A PF12253.8 CEP13936.1 - 1.8e-21 76.1 3.4 3.8e-21 75.0 3.4 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF4218 PF13960.6 CEP13939.1 - 6.9e-06 25.6 0.4 1.7e-05 24.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TSR PF18487.1 CEP13939.1 - 0.00074 19.7 7.0 0.00074 19.7 7.0 1.8 2 0 0 2 2 2 1 Thrombospondin type 1 repeat zf-ISL3 PF14690.6 CEP13939.1 - 0.017 15.8 0.6 0.041 14.5 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Wyosine_form PF08608.12 CEP13943.1 - 0.11 12.9 0.0 0.66 10.4 0.0 2.2 2 0 0 2 2 2 0 Wyosine base formation PGAP1 PF07819.13 CEP13944.1 - 1.8e-83 279.8 0.1 2.5e-83 279.4 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CEP13944.1 - 7.2e-06 26.8 0.0 2.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CEP13944.1 - 0.00026 20.9 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CEP13944.1 - 0.0022 17.7 0.0 0.0067 16.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 CEP13944.1 - 0.0051 16.3 0.4 0.017 14.6 0.4 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CEP13944.1 - 0.0065 15.8 0.1 0.03 13.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CEP13944.1 - 0.029 13.7 0.2 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 CEP13944.1 - 0.049 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 CEP13944.1 - 0.054 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_L28e PF01778.17 CEP13945.1 - 1.2e-33 116.3 5.5 1.5e-33 116.0 5.5 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family RNA_pol_Rpb1_5 PF04998.17 CEP13945.1 - 0.025 14.0 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 NUFIP1 PF10453.9 CEP13946.1 - 4.5e-13 48.8 6.8 4.5e-13 48.8 6.8 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 CEP13946.1 - 5.1e-06 26.3 5.4 9.5e-06 25.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CEP13946.1 - 4.5e-05 23.2 4.3 8.6e-05 22.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CEP13946.1 - 0.00052 19.7 6.0 0.00096 18.9 6.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CEP13946.1 - 0.007 17.1 0.9 0.02 15.6 0.5 2.0 1 1 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 CEP13946.1 - 0.04 14.1 0.8 0.13 12.5 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger containing family Usp PF00582.26 CEP13947.1 - 0.024 15.1 0.0 0.025 15.1 0.0 1.1 1 0 0 1 1 1 0 Universal stress protein family Prenyltransf PF01255.19 CEP13947.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Arrestin_N PF00339.29 CEP13948.1 - 1.2e-12 48.2 0.0 1.3e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ferritin PF00210.24 CEP13949.1 - 4.4e-08 33.2 0.5 4.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Ferritin-like domain SelR PF01641.18 CEP13949.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SelR domain 2OG-FeII_Oxy_3 PF13640.6 CEP13950.1 - 2.2e-15 57.3 0.0 4.8e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CEP13950.1 - 0.00016 22.3 0.0 0.0003 21.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB_2 PF02214.22 CEP13951.1 - 0.0012 19.1 0.1 0.016 15.5 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_M99_m PF17130.4 CEP13951.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 TPT PF03151.16 CEP13952.1 - 1.7e-45 155.7 17.2 7.1e-32 110.9 5.2 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 CEP13952.1 - 1e-09 38.1 14.2 3.1e-07 29.9 6.3 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 CEP13952.1 - 3.3e-07 30.5 11.9 3.3e-07 30.5 11.9 2.5 2 1 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.19 CEP13952.1 - 0.035 14.8 1.0 0.035 14.8 1.0 2.7 2 1 1 3 3 3 0 Small Multidrug Resistance protein Metalloenzyme PF01676.18 CEP13953.1 - 5e-79 265.2 0.1 5.8e-79 265.0 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CEP13953.1 - 1.3e-76 256.9 0.0 1.8e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 CEP13953.1 - 4.2e-06 26.6 0.0 8.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CEP13953.1 - 3.7e-05 23.3 0.0 0.00013 21.5 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 CEP13953.1 - 0.013 14.5 0.1 0.03 13.3 0.1 1.6 1 0 0 1 1 1 0 Alkaline phosphatase PglZ PF08665.12 CEP13953.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 PglZ domain Tom22 PF04281.13 CEP13955.1 - 6.4e-37 126.4 2.5 1.2e-36 125.6 2.5 1.4 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GvpG PF05120.12 CEP13955.1 - 3.3 7.8 7.1 0.29 11.2 1.9 2.0 2 1 0 2 2 2 0 Gas vesicle protein G Mre11_DNA_bind PF04152.14 CEP13956.1 - 9.1e-43 146.5 0.9 1.8e-42 145.5 0.2 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CEP13956.1 - 1.2e-14 55.3 1.7 1.9e-14 54.7 1.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP13956.1 - 0.0005 20.3 0.0 0.0019 18.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rad50_zn_hook PF04423.14 CEP13959.1 - 0.075 12.9 2.6 0.24 11.3 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Fer4_3 PF12798.7 CEP13959.1 - 0.33 12.0 0.2 0.33 12.0 0.2 3.5 3 1 0 3 3 3 0 4Fe-4S binding domain Fer4 PF00037.27 CEP13959.1 - 0.78 9.7 9.4 0.54 10.2 0.3 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Med17 PF10156.9 CEP13960.1 - 7.6e-131 437.0 5.5 1e-130 436.6 5.5 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex TMEM237 PF15383.6 CEP13960.1 - 0.023 13.8 0.2 0.46 9.5 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 237 Herpes_capsid PF06112.11 CEP13960.1 - 0.042 13.9 2.7 0.093 12.8 2.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4716 PF15837.5 CEP13960.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) Glyco_transf_64 PF09258.10 CEP13961.1 - 2.5e-37 128.5 0.4 4e-37 127.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 CEP13961.1 - 1.9e-19 70.2 11.7 1.8e-18 67.0 6.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 CEP13961.1 - 0.00019 21.5 0.3 0.00046 20.2 0.3 1.7 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 CEP13961.1 - 0.0017 17.8 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative B12D PF06522.11 CEP13963.1 - 2.2e-19 69.0 0.0 2.6e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2834 PF11196.8 CEP13963.1 - 0.1 13.0 0.4 0.14 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) PIF1 PF05970.14 CEP13965.1 - 1e-30 107.2 0.0 1.3e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP13965.1 - 2e-05 22.8 0.0 2.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP13965.1 - 0.004 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HTH_23 PF13384.6 CEP13966.1 - 0.00013 21.7 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP13966.1 - 0.00021 21.4 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP13966.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 CEP13966.1 - 0.014 16.0 0.0 0.031 14.9 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 CEP13966.1 - 0.041 13.8 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 'Paired box' domain TrmB PF01978.19 CEP13966.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Chromo PF00385.24 CEP13967.1 - 5.9e-09 35.7 0.2 1e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP13968.1 - 1.1e-12 48.2 0.0 3.6e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP13968.1 - 3e-08 33.6 0.1 5.3e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP13968.1 - 6.8e-07 29.4 0.2 1.4e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 H2C2 zinc finger WD40 PF00400.32 CEP13972.1 - 2.4e-49 164.3 23.3 8.9e-09 35.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP13972.1 - 8.9e-13 48.4 1.0 0.094 13.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP13972.1 - 8.1e-06 25.8 0.0 6.3e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP13972.1 - 0.00072 18.6 0.3 0.45 9.4 0.0 3.7 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP13972.1 - 0.0018 17.0 11.2 0.032 12.9 0.4 5.1 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CEP13972.1 - 0.0041 15.7 0.0 2 6.8 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Aminotran_3 PF00202.21 CEP13973.1 - 4.7e-48 163.8 0.0 1.5e-44 152.3 0.0 3.4 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 CEP13973.1 - 4.7e-18 65.7 0.0 7.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 CEP13974.1 - 4.1e-20 71.7 0.2 1.3e-19 70.1 0.1 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CEP13974.1 - 1.1e-14 55.2 0.1 1.5e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 CEP13974.1 - 0.13 12.4 0.6 0.67 10.1 0.5 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF1394 PF07159.12 CEP13975.1 - 3.5e-104 348.3 0.0 3.9e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) RILP PF11461.8 CEP13975.1 - 0.064 13.5 0.0 0.3 11.3 0.0 2.2 3 0 0 3 3 3 0 Rab interacting lysosomal protein Ribosomal_L22 PF00237.19 CEP13976.1 - 1.7e-40 137.4 0.1 2.2e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L15e PF00827.17 CEP13977.1 - 9e-89 296.3 9.7 1e-88 296.1 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-CCCH PF00642.24 CEP13981.1 - 2.4e-12 46.4 16.1 4.7e-07 29.6 2.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CEP13981.1 - 0.0009 19.0 0.1 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CEP13981.1 - 0.014 15.5 2.9 0.014 15.5 2.9 2.7 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 CEP13981.1 - 0.067 13.4 6.7 0.27 11.4 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger containing family Ctr PF04145.15 CEP13982.1 - 1.8e-28 100.1 0.1 2.7e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Aminotran_1_2 PF00155.21 CEP13983.1 - 1.3e-29 103.5 0.0 1.4e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CEP13983.1 - 1.4e-10 40.6 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF1699 PF08004.11 CEP13984.1 - 0.053 13.2 0.1 0.55 9.9 0.1 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) NitrOD1 PF18549.1 CEP13984.1 - 0.072 13.1 0.1 0.34 10.9 0.1 2.2 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 CDT1 PF08839.11 CEP13984.1 - 0.077 13.3 1.0 4.9 7.4 0.1 3.4 3 0 0 3 3 3 0 DNA replication factor CDT1 like SET PF00856.28 CEP13985.1 - 1.1e-08 35.6 0.0 3.2e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 SET domain RT_RNaseH PF17917.1 CEP13986.1 - 3.5e-25 88.3 0.0 6.3e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP13986.1 - 5.9e-13 48.7 0.3 1.1e-12 47.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase adh_short PF00106.25 CEP13991.1 - 1.4e-34 119.3 0.2 1.8e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP13991.1 - 7e-30 104.3 0.1 8.1e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP13991.1 - 9.5e-06 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CEP13991.1 - 2.3e-05 24.3 0.1 4e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP13991.1 - 0.0057 16.2 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CEP13991.1 - 0.058 12.8 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CEP13991.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) zf-C2H2_4 PF13894.6 CEP13993.1 - 0.0033 18.1 0.3 0.0033 18.1 0.3 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP13993.1 - 0.0035 17.7 0.4 0.0035 17.7 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.7 CEP13993.1 - 0.083 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CEP13993.1 - 0.087 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CEP13993.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DNA_pol_phi PF04931.13 CEP13993.1 - 4.7 5.2 9.9 7.3 4.6 8.6 1.7 2 0 0 2 2 2 0 DNA polymerase phi PrlF_antitoxin PF15937.5 CEP13995.1 - 0.02 15.3 0.2 0.044 14.2 0.2 1.8 1 1 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin UQ_con PF00179.26 CEP13995.1 - 0.031 13.9 0.7 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme DUF4196 PF13846.6 CEP13995.1 - 0.063 13.5 2.7 0.087 13.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) MAGE_N PF12440.8 CEP13997.1 - 6.9 7.4 9.6 6.6 7.5 6.3 2.5 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal DHR10 PF18595.1 CEP13998.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Lzipper-MIP1 PF14389.6 CEP13998.1 - 0.027 14.7 0.2 0.059 13.7 0.2 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 CEP13998.1 - 0.049 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5082 PF16888.5 CEP13998.1 - 0.072 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 CEP13998.1 - 0.09 13.1 0.2 0.19 12.1 0.2 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain CCDC106 PF15794.5 CEP13998.1 - 0.099 12.3 0.8 0.14 11.9 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 betaPIX_CC PF16523.5 CEP13998.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Transposase_21 PF02992.14 CEP13999.1 - 0.053 12.8 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 zf-C2H2_10 PF16588.5 CEP14000.1 - 0.017 14.8 1.8 0.017 14.8 1.8 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 CEP14000.1 - 0.048 13.6 2.3 0.092 12.7 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CEP14000.1 - 0.06 13.4 5.3 0.06 13.4 5.3 2.5 2 1 0 2 2 2 0 Zinc knuckle Nucleoporin_N PF08801.11 CEP14001.1 - 2.1e-14 53.1 0.2 1.6e-10 40.4 0.0 2.9 3 0 0 3 3 3 2 Nup133 N terminal like GAGBD PF16828.5 CEP14001.1 - 0.065 13.3 0.1 0.065 13.3 0.1 2.8 3 0 0 3 3 3 0 GAG-binding domain on surface antigen Aa_trans PF01490.18 CEP14002.1 - 2.6e-16 59.3 28.2 2.6e-16 59.3 28.2 2.0 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEP14002.1 - 9.3e-06 24.9 15.5 9.3e-06 24.9 15.5 1.9 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SMK-1 PF04802.15 CEP14003.1 - 2.1e-59 200.6 2.8 2.1e-59 200.6 2.8 2.0 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 CEP14003.1 - 0.0044 17.3 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain SDA1 PF05285.12 CEP14003.1 - 0.029 13.8 19.4 0.047 13.1 19.4 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CEP14003.1 - 0.2 10.9 22.7 0.35 10.2 22.7 1.3 1 0 0 1 1 1 0 BUD22 PDZ_5 PF17817.1 CEP14004.1 - 0.2 11.9 1.2 0.41 11.0 0.5 2.0 2 1 0 2 2 2 0 PDZ domain Kelch_4 PF13418.6 CEP14005.1 - 3.1e-22 78.3 6.2 1.4e-08 34.6 0.2 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP14005.1 - 1.3e-21 75.9 6.0 4.9e-06 26.0 0.2 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CEP14005.1 - 1.9e-21 75.2 5.2 0.00015 21.6 0.1 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CEP14005.1 - 7.1e-21 73.7 5.8 7.6e-05 22.9 0.0 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CEP14005.1 - 1.1e-20 73.1 4.4 1.6e-05 24.8 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CEP14005.1 - 6.9e-18 64.5 3.3 0.002 18.4 0.0 5.9 5 1 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 CEP14005.1 - 4.2e-13 49.5 0.0 1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 CEP14006.1 - 2.6e-72 243.3 0.1 2.6e-72 243.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14006.1 - 4.1e-52 177.0 0.1 4.1e-52 177.0 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 CEP14006.1 - 4.7e-20 71.7 0.0 1.8e-19 69.8 0.0 2.1 2 0 0 2 2 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CEP14006.1 - 2e-07 30.6 0.1 3e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP14006.1 - 1.4e-05 24.1 13.2 0.00017 20.5 13.2 2.1 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP14006.1 - 0.0028 16.6 6.1 0.0073 15.3 6.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP14006.1 - 0.0047 16.9 0.9 0.21 11.5 0.2 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF3915 PF13054.6 CEP14006.1 - 0.031 14.2 4.0 0.082 12.9 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RIO1 PF01163.22 CEP14006.1 - 0.049 13.2 0.1 0.049 13.2 0.1 2.4 2 1 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 CEP14006.1 - 0.055 12.5 0.3 0.098 11.7 0.3 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 dsRBD2 PF17842.1 CEP14006.1 - 0.93 9.7 4.8 2 8.6 4.8 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Apis_Csd PF11671.8 CEP14006.1 - 3.2 7.8 8.9 6.8 6.7 8.9 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein CDC45 PF02724.14 CEP14006.1 - 4.3 5.5 11.2 7 4.8 11.2 1.2 1 0 0 1 1 1 0 CDC45-like protein MMR1 PF08505.10 CEP14006.1 - 6.8 6.9 13.8 14 5.9 13.8 1.6 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein VIR_N PF15912.5 CEP14006.1 - 9.1 5.8 13.9 15 5.0 13.9 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Asp PF00026.23 CEP14007.1 - 1.5e-79 267.7 0.0 1.8e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP14007.1 - 1e-15 58.4 0.0 4.8e-14 53.0 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEP14007.1 - 1.5e-05 25.6 0.0 0.23 12.1 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CEP14007.1 - 0.00023 21.6 0.0 1.4 9.5 0.0 3.6 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CEP14007.1 - 0.029 14.2 0.0 1 9.1 0.0 2.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF5056 PF16479.5 CEP14008.1 - 0.057 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) PDEase_I PF00233.19 CEP14009.1 - 7.3e-72 241.9 1.7 9.2e-71 238.3 1.7 2.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CEP14009.1 - 0.0031 17.7 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 HD domain SUIM_assoc PF16619.5 CEP14009.1 - 0.031 14.3 5.1 85 3.3 9.9 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pex14_N PF04695.13 CEP14009.1 - 9.5 6.9 8.0 0.98 10.1 3.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Malic_M PF03949.15 CEP14010.1 - 9.5e-85 284.0 0.3 1.3e-84 283.5 0.3 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEP14010.1 - 2.8e-56 190.2 0.0 5.4e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain zinc_ribbon_9 PF14369.6 CEP14011.1 - 0.0047 17.2 1.1 0.014 15.6 1.1 1.9 1 0 0 1 1 1 1 zinc-ribbon RGS PF00615.19 CEP14012.1 - 1.5e-10 41.4 0.2 4e-10 40.0 0.2 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain F-box PF00646.33 CEP14013.1 - 0.0034 17.2 0.1 0.0073 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain PGM_PMM_I PF02878.16 CEP14014.1 - 2e-35 121.5 0.1 3.5e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CEP14014.1 - 1.4e-28 99.4 0.0 4.2e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CEP14014.1 - 1.8e-16 60.6 0.1 4.5e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CEP14014.1 - 4.7e-09 36.3 0.0 1.6e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Autophagy_N PF03986.13 CEP14015.1 - 1.6e-44 151.2 4.8 3.3e-44 150.2 4.8 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CEP14015.1 - 3.1e-20 72.5 0.7 7.6e-20 71.2 0.7 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CEP14015.1 - 1.7e-15 56.2 3.3 2.9e-15 55.4 3.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Cullin PF00888.22 CEP14016.1 - 3e-195 650.5 4.8 3.9e-195 650.1 4.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CEP14016.1 - 6.6e-20 70.9 4.3 2.5e-19 69.0 2.9 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 CEP14016.1 - 0.0005 20.5 0.5 0.0025 18.2 0.0 2.5 2 0 0 2 2 2 1 Phage tail assembly chaperone protein, TAC DUF3658 PF12395.8 CEP14016.1 - 0.078 12.9 1.7 0.16 11.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function TFCD_C PF12612.8 CEP14016.1 - 0.082 12.7 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF592 PF04574.13 CEP14016.1 - 1.3 8.8 6.7 0.73 9.6 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF592) MukF_M PF17192.4 CEP14016.1 - 3.9 7.2 5.8 3.4 7.4 0.1 3.2 4 0 0 4 4 4 0 MukF middle domain AnfG_VnfG PF03139.15 CEP14016.1 - 8 6.6 10.3 0.25 11.5 1.5 2.9 3 1 1 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Ank_2 PF12796.7 CEP14017.1 - 1.1e-12 48.4 1.1 4.2e-09 36.9 0.4 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP14017.1 - 5.7e-10 39.5 0.3 1e-06 29.2 0.1 3.6 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP14017.1 - 2e-08 34.3 0.6 0.00014 22.1 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP14017.1 - 2.4e-08 33.6 0.9 0.0041 17.5 0.1 3.5 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CEP14017.1 - 4.9e-08 33.1 0.5 0.0018 18.6 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat LEA_2 PF03168.13 CEP14018.1 - 0.15 12.6 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF900 PF05990.12 CEP14019.1 - 3.8e-06 26.6 0.0 1.6e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 CEP14019.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Arrestin_C PF02752.22 CEP14020.1 - 1.4e-18 67.6 0.1 1.6e-16 61.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP14020.1 - 4.5e-15 56.0 0.0 9.6e-15 54.9 0.0 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP14020.1 - 0.00077 19.2 0.0 0.0027 17.4 0.0 1.9 1 1 0 1 1 1 1 Arrestin_N terminal like MIF4G PF02854.19 CEP14021.1 - 5.3e-45 153.7 1.1 1.3e-44 152.4 1.1 1.7 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CEP14021.1 - 1.8e-07 31.2 0.1 9.7e-07 28.9 0.1 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 CEP14021.1 - 0.00032 20.6 0.1 0.0011 18.9 0.1 2.0 1 0 0 1 1 1 1 MA3 domain SOG2 PF10428.9 CEP14021.1 - 0.0035 16.6 14.4 0.0035 16.6 14.4 4.5 2 1 2 4 4 4 1 RAM signalling pathway protein Fungal_trans PF04082.18 CEP14022.1 - 5.4e-19 68.2 2.2 5.4e-19 68.2 2.2 2.5 3 1 1 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP14022.1 - 1.6e-10 40.9 6.0 2.8e-10 40.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nodulin-like PF06813.13 CEP14023.1 - 1.7e-09 37.5 5.3 4.2e-09 36.3 5.3 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 CEP14023.1 - 3.2e-08 32.9 41.0 8.4e-07 28.2 15.3 3.1 2 1 2 4 4 4 2 Major Facilitator Superfamily SUIM_assoc PF16619.5 CEP14023.1 - 0.017 15.2 1.0 0.017 15.2 1.0 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Olduvai PF06758.13 CEP14023.1 - 0.055 13.7 1.0 0.12 12.7 1.0 1.5 1 0 0 1 1 1 0 Olduvai domain Mit_KHE1 PF10173.9 CEP14023.1 - 0.15 12.1 0.0 8.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4834 PF16118.5 CEP14023.1 - 0.24 12.4 4.1 0.49 11.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CEP14023.1 - 0.46 10.2 1.9 16 5.2 0.2 2.5 2 0 0 2 2 2 0 FAM176 family RIFIN PF02009.16 CEP14024.1 - 1.3 8.9 6.7 1.4 8.8 6.7 1.0 1 0 0 1 1 1 0 Rifin Cation_efflux PF01545.21 CEP14025.1 - 1.1e-26 93.8 12.4 1.4e-26 93.5 12.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CEP14025.1 - 1.5e-08 34.7 0.1 4.3e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter GCR1_C PF12550.8 CEP14027.1 - 0.00058 20.1 0.8 0.0017 18.7 0.8 1.7 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.32 CEP14028.1 - 1.9e-21 75.9 13.6 3.1e-07 31.0 0.3 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP14028.1 - 3.1e-07 30.6 2.6 0.0077 16.5 0.2 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CEP14028.1 - 0.015 15.3 0.4 0.025 14.5 0.4 1.4 1 0 0 1 1 1 0 LisH PD40 PF07676.12 CEP14028.1 - 0.25 11.3 1.4 22 5.2 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 CEP14029.1 - 3.1e-86 283.2 1.4 1.1e-20 73.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP14029.1 - 5.2e-28 97.0 0.8 5.2e-28 97.0 0.8 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 CEP14029.1 - 3.8e-08 33.3 0.2 0.42 10.8 0.0 5.0 4 1 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CEP14029.1 - 1.5e-06 28.1 1.1 7.8 6.6 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CEP14029.1 - 1.1e-05 25.3 0.0 7.8 6.3 0.0 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 CEP14029.1 - 0.00015 21.8 4.7 0.67 10.0 0.1 4.4 3 1 1 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 CEP14029.1 - 0.00017 21.3 0.1 0.26 11.1 0.0 4.4 5 0 0 5 5 5 1 Occluded RNA-recognition motif OB_RNB PF08206.11 CEP14029.1 - 0.0017 18.0 0.3 4.5 7.0 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain SET_assoc PF11767.8 CEP14029.1 - 0.0052 16.4 0.1 4.3 7.1 0.0 3.6 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated SH3_1 PF00018.28 CEP14030.1 - 1.5e-16 59.7 0.6 2.6e-16 58.9 0.6 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP14030.1 - 3.1e-13 49.2 0.1 5.1e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP14030.1 - 6.5e-11 41.9 0.1 1e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Mito_carr PF00153.27 CEP14031.1 - 8.6e-58 192.3 1.6 1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP14031.1 - 0.0055 15.9 0.5 2.2 7.4 0.1 2.7 3 1 0 3 3 3 2 Gammaproteobacterial serine protease GHMP_kinases_N PF00288.26 CEP14032.1 - 6e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEP14032.1 - 0.00081 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal CotH PF08757.11 CEP14033.1 - 4.9e-35 121.6 0.0 1e-34 120.5 0.0 1.4 1 1 0 1 1 1 1 CotH kinase protein Kelch_5 PF13854.6 CEP14034.1 - 1.3e-21 76.1 4.7 1.5e-05 24.8 0.7 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CEP14034.1 - 2.5e-15 56.2 12.0 0.0028 17.6 0.0 6.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP14034.1 - 8e-15 54.2 14.8 2.8e-05 23.6 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CEP14034.1 - 1.8e-13 50.3 8.3 0.047 14.0 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CEP14034.1 - 3.3e-11 42.7 4.0 0.0079 16.1 0.2 6.1 6 0 0 6 6 6 3 Kelch motif ANAPC_CDC26 PF10471.9 CEP14034.1 - 1.7e-07 32.0 3.8 1.7e-07 32.0 3.8 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 Kelch_3 PF13415.6 CEP14034.1 - 3.9e-05 23.8 14.3 0.031 14.6 0.7 5.8 6 1 0 6 6 6 2 Galactose oxidase, central domain SpoIIIAH PF12685.7 CEP14034.1 - 0.094 12.5 0.6 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein EphA2_TM PF14575.6 CEP14034.1 - 0.11 13.4 0.0 0.37 11.7 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Fungal_trans PF04082.18 CEP14035.1 - 6.7e-16 58.1 1.5 6.7e-16 58.1 1.5 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain AMP-binding PF00501.28 CEP14036.1 - 1.7e-83 280.6 0.0 2.1e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP14036.1 - 3.4e-18 66.4 0.3 6.8e-18 65.4 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CEP14036.1 - 0.03 13.2 0.0 0.52 9.1 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter RTX_C PF08339.10 CEP14036.1 - 0.038 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain F-box-like PF12937.7 CEP14037.1 - 5.5e-06 26.2 0.3 1.7e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like zinc-ribbons_6 PF07191.12 CEP14038.1 - 0.032 14.2 10.2 1.1 9.3 6.5 2.3 1 1 1 2 2 2 0 zinc-ribbons Siva PF05458.12 CEP14038.1 - 0.13 12.0 5.9 0.17 11.5 5.9 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DZR PF12773.7 CEP14038.1 - 1.4 9.0 12.5 6.4 6.9 12.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon ADH_zinc_N PF00107.26 CEP14039.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP14039.1 - 1.3e-05 25.0 0.1 3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.6 CEP14039.1 - 0.084 13.4 0.0 1.1 9.8 0.0 2.6 2 1 0 2 2 2 0 CoA binding domain Lon_C PF05362.13 CEP14040.1 - 5.3e-72 241.7 0.4 8.9e-72 240.9 0.4 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CEP14040.1 - 2.3e-17 63.6 0.0 8.5e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CEP14040.1 - 5.5e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 CEP14040.1 - 9.9e-09 35.1 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CEP14040.1 - 3.9e-06 26.9 0.1 2.6e-05 24.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP14040.1 - 8.9e-05 22.3 0.0 0.00026 20.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CEP14040.1 - 0.00024 21.4 0.3 0.011 16.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP14040.1 - 0.00059 20.3 0.0 0.0023 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 CEP14040.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 CEP14040.1 - 0.0025 18.4 0.1 0.0085 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF3445 PF11927.8 CEP14040.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) AAA_2 PF07724.14 CEP14040.1 - 0.0088 16.2 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CEP14040.1 - 0.011 15.8 0.0 0.12 12.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CEP14040.1 - 0.011 16.1 0.0 0.041 14.3 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 CEP14040.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP14040.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 CEP14040.1 - 0.021 14.6 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 CEP14040.1 - 0.022 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CEP14040.1 - 0.022 14.7 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CEP14040.1 - 0.025 14.5 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 CEP14040.1 - 0.033 14.7 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CEP14040.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CEP14040.1 - 0.11 13.0 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 CEP14040.1 - 0.12 12.7 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain SKI PF01202.22 CEP14040.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_17 PF13207.6 CEP14040.1 - 0.17 12.3 0.1 0.65 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain F-box-like PF12937.7 CEP14041.1 - 0.0001 22.1 0.4 0.001 18.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP14041.1 - 0.14 12.1 0.0 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 CEP14041.1 - 0.2 12.2 2.7 3.5 8.2 1.4 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DNA_binding_1 PF01035.20 CEP14042.1 - 6e-21 74.4 0.0 8.7e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Striatin PF08232.12 CEP14043.1 - 6.9e-46 156.7 0.1 6.9e-46 156.7 0.1 2.5 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 CEP14043.1 - 3e-24 84.8 4.1 6.4e-08 33.1 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP14043.1 - 7.8e-08 32.5 0.2 0.091 13.1 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEP14043.1 - 0.00023 20.0 0.3 0.42 9.3 0.0 2.9 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 CEP14043.1 - 0.0083 14.8 3.0 0.29 9.7 0.1 3.6 2 2 1 4 4 4 1 Nucleoporin Nup120/160 PH_8 PF15409.6 CEP14043.1 - 0.048 13.9 0.0 6.7 7.1 0.0 2.9 2 1 1 3 3 3 0 Pleckstrin homology domain TFIIA PF03153.13 CEP14043.1 - 0.26 11.2 16.6 0.38 10.7 16.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5521 PF17659.1 CEP14043.1 - 5.5 4.7 9.6 9.7 3.9 9.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Pho88 PF10032.9 CEP14044.1 - 7.9e-50 168.6 0.0 9e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ras PF00071.22 CEP14045.1 - 2.7e-58 196.2 0.4 3.1e-58 195.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP14045.1 - 4.1e-33 114.1 0.1 5.9e-33 113.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP14045.1 - 6.4e-17 61.5 0.1 7.9e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP14045.1 - 1.7e-08 34.5 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP14045.1 - 1.2e-07 31.4 0.1 1.4e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP14045.1 - 2.3e-06 27.3 0.2 9e-06 25.4 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEP14045.1 - 0.0002 20.8 0.1 0.0018 17.8 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CEP14045.1 - 0.00075 19.4 0.2 0.14 12.0 0.0 2.4 1 1 2 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 CEP14045.1 - 0.0016 18.0 0.0 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 CEP14045.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 CEP14045.1 - 0.027 14.2 0.1 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CEP14045.1 - 0.26 10.4 1.2 6.2 5.9 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Complex1_LYR PF05347.15 CEP14046.1 - 2.9e-06 27.2 1.1 4.3e-05 23.5 0.5 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Ran-binding PF05508.11 CEP14046.1 - 0.033 13.2 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 RanGTP-binding protein Arm PF00514.23 CEP14047.1 - 3.2e-13 49.2 6.3 0.00037 20.4 0.0 7.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEP14047.1 - 5.9e-06 26.7 0.0 1.8 9.2 0.0 4.6 4 0 0 4 4 4 3 HEAT-like repeat Cytidylate_kin PF02224.18 CEP14048.1 - 1.9e-63 214.0 4.2 1.1e-31 110.2 1.0 2.0 2 0 0 2 2 2 2 Cytidylate kinase Cytidylate_kin2 PF13189.6 CEP14048.1 - 1.8e-06 28.2 0.6 1.9e-05 24.9 0.6 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 CEP14048.1 - 0.00021 21.7 0.4 0.00047 20.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP14048.1 - 0.0008 20.0 0.0 0.0041 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP14048.1 - 0.0035 17.5 0.2 0.012 15.8 0.0 2.0 2 1 1 3 3 3 1 AAA domain SKI PF01202.22 CEP14048.1 - 0.0036 17.5 0.7 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 Shikimate kinase ADK PF00406.22 CEP14048.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase dNK PF01712.19 CEP14048.1 - 0.048 13.5 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 CEP14048.1 - 0.12 12.9 0.9 0.21 12.1 0.9 1.7 1 1 0 1 1 1 0 ABC transporter Zip PF02535.22 CEP14049.1 - 2.2e-35 122.4 20.9 8.7e-34 117.2 20.9 2.7 1 1 0 1 1 1 1 ZIP Zinc transporter 7TM-7TMR_HD PF07698.11 CEP14049.1 - 0.0015 18.3 6.8 0.0015 18.3 6.8 2.1 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase DUF308 PF03729.13 CEP14049.1 - 0.037 14.4 0.1 0.037 14.4 0.1 3.3 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) DNA_pol3_beta_3 PF02768.15 CEP14049.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain FTR1 PF03239.14 CEP14049.1 - 0.19 10.9 5.0 0.089 11.9 2.7 1.8 2 0 0 2 2 2 0 Iron permease FTR1 family CNDH2_C PF16858.5 CEP14050.1 - 0.0059 16.5 4.2 0.0085 16.0 4.2 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 CEP14050.1 - 0.025 14.0 24.9 0.041 13.3 24.9 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 CEP14050.1 - 2.8 7.0 35.4 5.1 6.1 35.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) F-box-like PF12937.7 CEP14051.1 - 8.3e-07 28.8 0.4 1.5e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP14051.1 - 0.00016 21.4 0.0 0.00082 19.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain eIF2A PF08662.11 CEP14052.1 - 1.3e-39 136.1 5.9 3.6e-35 121.6 0.9 5.2 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CEP14052.1 - 1.1e-05 25.1 0.0 2.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CEP14052.1 - 0.00017 22.3 0.9 0.034 15.0 0.5 4.1 3 1 1 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP14052.1 - 0.0034 17.7 0.3 35 4.8 0.0 5.9 6 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L4 PF00573.22 CEP14053.1 - 1.6e-41 142.1 0.9 1.6e-41 142.1 0.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CEP14053.1 - 4.9e-31 106.6 3.1 6.5e-31 106.2 0.9 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain JAB PF01398.21 CEP14054.1 - 1.1e-18 67.3 0.0 2.1e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 CEP14054.1 - 1.2e-17 64.2 0.8 2e-17 63.4 0.8 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 CEP14054.1 - 3.3e-06 26.9 0.0 7.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ribosomal_S20p PF01649.18 CEP14054.1 - 0.005 17.5 1.9 0.011 16.4 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S20 Clat_adaptor_s PF01217.20 CEP14055.1 - 6e-54 181.8 2.8 6.9e-54 181.6 2.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 CEP14056.1 - 2.7e-46 158.1 0.0 3.7e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.20 CEP14057.1 - 1.7e-36 124.3 0.3 6.5e-23 80.7 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CEP14057.1 - 3.9e-27 95.4 5.2 8.3e-18 65.0 3.9 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP14057.1 - 0.00022 21.5 7.1 0.64 10.4 0.0 5.6 4 1 2 6 6 6 1 Thioredoxin-like OST3_OST6 PF04756.13 CEP14057.1 - 0.00044 19.7 3.8 0.016 14.6 0.6 3.7 4 0 0 4 4 4 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CEP14057.1 - 0.0031 17.9 0.2 2.4 8.7 0.2 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEP14057.1 - 0.009 16.2 0.1 0.049 13.8 0.1 2.3 1 0 0 1 1 1 1 Thioredoxin-like 6PGD PF00393.19 CEP14058.1 - 2.8e-131 437.2 0.0 3.6e-131 436.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEP14058.1 - 3e-53 180.2 0.0 4.5e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEP14058.1 - 0.0088 16.3 0.1 0.12 12.7 0.0 2.6 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CEP14058.1 - 0.0099 16.4 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CEP14058.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Band_7 PF01145.25 CEP14059.1 - 7.4e-32 110.8 0.2 1e-31 110.4 0.2 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CEP14059.1 - 0.00077 19.2 0.1 0.0015 18.3 0.1 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family DivIVA PF05103.13 CEP14059.1 - 0.11 12.6 1.3 0.19 11.8 1.3 1.3 1 0 0 1 1 1 0 DivIVA protein Band_7 PF01145.25 CEP14060.1 - 6.1e-29 101.3 0.3 9.2e-29 100.7 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family CAP PF00188.26 CEP14061.1 - 5.4e-23 82.2 9.6 3e-22 79.8 9.6 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Diphthami_syn_2 PF01902.17 CEP14062.1 - 6.6e-24 84.6 0.0 9.5e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Diphthamide synthase ACBP PF00887.19 CEP14063.1 - 2.1e-22 79.1 0.1 4.5e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 CEP14063.1 - 4.2e-14 52.9 0.2 7.4e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP14063.1 - 4.5e-14 52.6 0.2 9.6e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP14063.1 - 1.2e-13 50.9 0.1 1.6e-08 34.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP14063.1 - 6.6e-12 45.3 0.4 8.4e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CEP14063.1 - 3.3e-10 39.3 0.0 0.00055 20.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.32 CEP14064.1 - 4.3e-17 62.2 12.8 0.0079 17.0 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP14064.1 - 4.9e-15 55.6 3.6 0.0012 19.1 0.1 6.8 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP14064.1 - 0.00019 20.5 0.5 0.07 12.1 0.1 3.5 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CEP14064.1 - 0.0034 17.0 2.0 0.017 14.7 1.4 2.5 2 1 0 2 2 2 1 PQQ-like domain GLE1 PF07817.13 CEP14066.1 - 3.2e-55 187.1 0.4 3.2e-55 187.1 0.4 2.0 2 0 0 2 2 2 1 GLE1-like protein DUF913 PF06025.12 CEP14066.1 - 9 5.2 12.4 15 4.4 12.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GCP_N_terminal PF17681.1 CEP14067.1 - 1e-94 317.6 1.8 3.9e-94 315.7 0.1 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEP14067.1 - 1.4e-89 300.6 8.4 2.9e-89 299.6 8.4 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Allantoicase PF03561.15 CEP14068.1 - 1.8e-82 274.4 0.0 1.2e-43 148.5 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 CEP14068.1 - 1.6e-53 181.3 0.0 2.4e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate lyase Dor1 PF04124.12 CEP14069.1 - 9.9e-65 218.4 4.5 2e-64 217.4 4.5 1.5 1 0 0 1 1 1 1 Dor1-like family Spc7_C2 PF15577.6 CEP14069.1 - 0.011 15.8 0.5 0.035 14.2 0.0 2.0 2 0 0 2 2 2 0 Spc7_C2 MULE PF10551.9 CEP14070.1 - 1.1e-21 77.1 0.2 3.2e-21 75.6 0.1 1.9 2 0 0 2 2 2 1 MULE transposase domain Transglut_prok PF09017.10 CEP14070.1 - 0.0081 15.5 0.7 0.21 10.9 0.2 2.2 1 1 1 2 2 2 1 Microbial transglutaminase Terminase_3C PF17288.2 CEP14070.1 - 0.038 14.4 0.8 0.1 13.0 0.8 1.7 1 0 0 1 1 1 0 Terminase RNAseH like domain RGS-like PF09128.11 CEP14070.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Cu-oxidase PF00394.22 CEP14071.1 - 5.5e-35 120.8 0.0 2.8e-34 118.6 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEP14071.1 - 7.7e-31 106.6 1.2 4.4e-30 104.1 0.9 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEP14071.1 - 5.3e-20 71.6 17.5 2.7e-10 40.1 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase A2M PF00207.22 CEP14071.1 - 0.072 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin family DUF3425 PF11905.8 CEP14072.1 - 9.9e-16 57.8 3.1 1.5e-15 57.3 1.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEP14072.1 - 5.9e-08 32.7 8.7 1.5e-07 31.4 8.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 CEP14072.1 - 0.005 16.6 0.6 0.011 15.5 0.6 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 SUIM_assoc PF16619.5 CEP14072.1 - 0.0081 16.2 7.4 0.23 11.6 1.3 3.3 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 bZIP_2 PF07716.15 CEP14072.1 - 0.022 14.8 13.7 0.022 14.8 13.7 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DDE_3 PF13358.6 CEP14073.1 - 3.4e-05 23.6 0.0 0.0001 22.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.6 CEP14073.1 - 8.2e-05 22.6 0.6 0.00039 20.4 0.0 2.4 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.6 CEP14073.1 - 9.1e-05 22.1 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 CEP14073.1 - 9.4e-05 22.7 0.4 0.00023 21.4 0.4 1.7 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 CEP14073.1 - 0.00013 22.0 0.1 0.00037 20.5 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CEP14073.1 - 0.00022 21.8 0.0 0.00055 20.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.7 CEP14073.1 - 0.15 12.2 0.0 5.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1180 PF06679.12 CEP14073.1 - 0.27 11.6 0.1 0.27 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ubiquitin PF00240.23 CEP14074.1 - 3.9e-24 84.2 0.0 4.1e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP14074.1 - 2.3e-12 46.6 0.0 2.4e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CEP14074.1 - 0.0012 18.8 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CEP14074.1 - 0.029 14.8 0.0 0.07 13.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain AAA_23 PF13476.6 CEP14075.1 - 5.1e-17 63.0 1.6 5.1e-17 63.0 1.6 7.9 4 2 0 4 4 4 1 AAA domain Rad50_zn_hook PF04423.14 CEP14075.1 - 3.7e-06 26.7 0.1 3.7e-06 26.7 0.1 5.5 4 0 0 4 4 4 1 Rad50 zinc hook motif SbcCD_C PF13558.6 CEP14075.1 - 7.8e-05 22.8 0.0 0.00026 21.2 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF2322 PF10084.9 CEP14075.1 - 0.082 13.0 0.4 2 8.5 0.0 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Tex_YqgF PF16921.5 CEP14075.1 - 0.11 12.9 1.2 0.56 10.7 1.2 2.3 1 0 0 1 1 1 0 Tex protein YqgF-like domain SNURF PF07192.11 CEP14075.1 - 0.37 10.6 3.1 2.3 8.1 3.1 2.4 1 0 0 1 1 1 0 SNURF/RPN4 protein NPV_P10 PF05531.12 CEP14075.1 - 2.4 8.7 57.6 1.6 9.2 7.3 9.8 7 5 1 8 8 8 0 Nucleopolyhedrovirus P10 protein HicB_lk_antitox PF15919.5 CEP14075.1 - 3.5 7.8 6.0 3.6 7.7 2.0 2.8 1 1 1 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system DEAD PF00270.29 CEP14076.1 - 3e-45 154.1 0.1 4.9e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP14076.1 - 3.8e-27 94.8 3.0 8.5e-27 93.7 0.4 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP14076.1 - 2.1e-05 24.6 1.1 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CEP14076.1 - 0.0089 15.6 3.0 0.077 12.5 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 CEP14076.1 - 0.03 13.6 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3619 PF12279.8 CEP14076.1 - 0.17 12.2 1.1 0.42 10.9 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) API5 PF05918.11 CEP14076.1 - 0.25 10.1 7.4 0.37 9.5 7.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Spt20 PF12090.8 CEP14076.1 - 1.3 8.6 13.5 2.2 7.8 13.5 1.3 1 0 0 1 1 1 0 Spt20 family F-box-like PF12937.7 CEP14077.1 - 0.00017 21.4 2.9 0.00017 21.4 2.9 2.2 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 CEP14078.1 - 1.3e-22 80.2 32.1 2.6e-22 79.2 31.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5572 PF17733.1 CEP14078.1 - 4.6e-18 64.8 2.3 8.8e-18 63.9 2.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) HTH_23 PF13384.6 CEP14080.1 - 0.069 13.0 0.4 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain TerB_C PF15615.6 CEP14080.1 - 0.11 12.8 0.1 0.37 11.1 0.1 2.0 1 1 0 1 1 1 0 TerB-C domain SH3_9 PF14604.6 CEP14081.1 - 1e-07 31.7 0.2 1.9e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP14081.1 - 2.6e-07 30.2 0.1 4.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP14081.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ANAPC4_WD40 PF12894.7 CEP14083.1 - 6.8e-11 42.3 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4 PF12896.7 CEP14083.1 - 2.2e-08 33.8 1.0 3.4e-08 33.2 1.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Med21 PF11221.8 CEP14083.1 - 8.4 6.6 9.6 0.34 11.2 3.4 1.8 2 1 0 2 2 2 0 Subunit 21 of Mediator complex zf-CCHC PF00098.23 CEP14087.1 - 0.014 15.4 1.3 0.014 15.4 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF2951 PF11166.8 CEP14087.1 - 0.16 12.2 0.6 0.44 10.8 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_10 PF16588.5 CEP14087.1 - 0.26 11.0 6.0 0.33 10.7 1.3 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP14087.1 - 7 6.6 13.4 1.9 8.4 2.5 2.3 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 CEP14088.1 - 7.3e-25 87.3 0.1 1.2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP14088.1 - 1.2e-13 50.9 0.0 2.6e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP14088.1 - 5.9e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Abhydrolase_6 PF12697.7 CEP14089.1 - 2.8e-05 24.8 0.1 4.9e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEP14089.1 - 0.00028 20.6 0.2 0.00068 19.3 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CEP14089.1 - 0.0056 16.6 0.1 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 CEP14089.1 - 0.0081 15.4 0.2 0.019 14.3 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 CEP14089.1 - 0.0091 16.0 0.1 0.083 12.8 0.1 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) LRIF1 PF15741.5 CEP14090.1 - 0.0025 16.4 10.8 0.0033 16.0 10.8 1.1 1 0 0 1 1 1 1 Ligand-dependent nuclear receptor-interacting factor 1 Plasmodium_Vir PF05795.11 CEP14090.1 - 0.092 12.1 2.4 0.13 11.6 2.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3963 PF13124.6 CEP14090.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) DUF2207 PF09972.9 CEP14090.1 - 0.14 10.9 2.1 0.25 10.0 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Presenilin PF01080.17 CEP14090.1 - 0.61 8.8 7.4 0.84 8.3 7.4 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CEP14090.1 - 0.86 8.2 9.1 0.98 8.0 8.2 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Merozoite_SPAM PF07133.11 CEP14090.1 - 1.8 8.6 19.2 3 7.8 19.2 1.4 1 1 0 1 1 1 0 Merozoite surface protein (SPAM) TP53IP5 PF15331.6 CEP14090.1 - 3.4 7.8 16.8 6.3 6.9 16.8 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BAR_3 PF16746.5 CEP14091.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 BAR domain of APPL family Pkinase PF00069.25 CEP14092.1 - 7.6e-59 199.2 1.1 8.9e-59 199.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14092.1 - 6.8e-41 140.2 0.0 1.4e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP14092.1 - 3.9e-06 25.9 0.0 3.9e-06 25.9 0.0 3.0 2 1 0 2 2 2 1 Fungal protein kinase Ribosomal_S19e PF01090.19 CEP14093.1 - 2.9e-60 201.9 0.1 3.2e-60 201.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CEP14093.1 - 0.097 12.8 0.2 0.23 11.6 0.1 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain RhoGAP PF00620.27 CEP14094.1 - 1.6e-39 135.2 0.4 2.9e-39 134.3 0.4 1.4 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 CEP14094.1 - 0.027 14.6 0.4 0.071 13.3 0.4 1.7 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Carn_acyltransf PF00755.20 CEP14095.1 - 5e-170 567.0 0.1 5.8e-170 566.8 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Arrestin_C PF02752.22 CEP14096.1 - 4.4e-18 66.0 4.9 5.9e-13 49.4 0.1 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP14096.1 - 4.1e-16 59.4 0.0 4.1e-16 59.4 0.0 3.4 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 CEP14096.1 - 0.0049 15.9 0.2 0.036 13.1 0.0 2.0 1 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 26 Cwf_Cwc_15 PF04889.12 CEP14096.1 - 0.018 14.8 2.7 0.018 14.8 2.7 2.9 2 1 1 3 3 3 0 Cwf15/Cwc15 cell cycle control protein VPS9 PF02204.18 CEP14097.1 - 4.1e-14 52.7 2.3 5.6e-14 52.2 0.1 2.2 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain WW PF00397.26 CEP14098.1 - 1.4e-08 34.7 0.9 3.2e-08 33.5 0.9 1.6 1 0 0 1 1 1 1 WW domain SUIM_assoc PF16619.5 CEP14101.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RGS PF00615.19 CEP14103.1 - 1.8e-20 73.4 0.1 9.6e-20 71.0 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 CEP14103.1 - 1.1e-06 28.5 0.5 0.0029 17.6 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DJ-1_PfpI PF01965.24 CEP14104.1 - 2.8e-07 30.5 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Latrotoxin_C PF15658.6 CEP14104.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Latrotoxin C-terminal domain EF-hand_4 PF12763.7 CEP14105.1 - 3.3e-41 139.5 0.0 2.3e-16 59.6 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CEP14105.1 - 2e-07 31.4 0.0 0.013 15.9 0.2 4.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP14105.1 - 1.5e-05 24.2 7.3 0.76 9.5 0.0 5.3 6 0 0 6 6 6 2 EF hand UBA PF00627.31 CEP14105.1 - 7.8e-05 22.5 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_MLP1_2 PF07926.12 CEP14105.1 - 0.00028 20.9 21.9 0.00028 20.9 21.9 3.7 2 1 2 4 4 3 1 TPR/MLP1/MLP2-like protein EF-hand_6 PF13405.6 CEP14105.1 - 0.003 17.3 3.1 18 5.6 0.0 5.4 5 0 0 5 5 5 0 EF-hand domain Spc7 PF08317.11 CEP14105.1 - 0.0046 15.9 15.8 0.0046 15.9 15.8 2.2 1 1 1 2 2 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 CEP14105.1 - 0.0055 16.9 11.1 0.0055 16.9 11.1 3.4 1 1 3 4 4 3 1 TATA element modulatory factor 1 TATA binding DUF4636 PF15468.6 CEP14105.1 - 0.0059 16.3 2.7 0.0059 16.3 2.7 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4636) EF-hand_8 PF13833.6 CEP14105.1 - 0.0059 16.4 0.0 0.97 9.3 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair DUF4201 PF13870.6 CEP14105.1 - 0.05 13.3 26.2 0.57 9.9 16.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.14 CEP14105.1 - 0.14 12.1 13.6 1.3 8.9 2.7 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ERM PF00769.19 CEP14105.1 - 0.28 11.0 34.6 0.88 9.3 34.6 1.9 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 CEP14105.1 - 0.38 10.8 16.9 2.3 8.3 4.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CEP14105.1 - 0.6 10.1 19.0 0.66 10.0 17.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 CEP14105.1 - 1.1 9.5 25.2 0.071 13.4 8.7 3.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 CEP14105.1 - 2.1 9.3 32.6 2.8 8.9 15.1 3.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 CEP14105.1 - 3.5 6.9 36.4 0.056 12.7 11.7 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CEP14105.1 - 4 7.5 34.3 9.3 6.3 6.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 CEP14105.1 - 4.3 7.8 16.9 4.5 7.8 1.6 4.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 CEP14105.1 - 6.4 6.9 14.1 1.5 8.9 5.1 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 R3H PF01424.22 CEP14106.1 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 CEP14106.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.12 CEP14106.1 - 0.018 14.6 4.9 0.018 14.6 4.9 2.5 2 1 0 2 2 2 0 PT repeat RRM_2 PF04059.12 CEP14106.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Cut12 PF11500.8 CEP14106.1 - 7.1 6.6 7.7 0.59 10.1 2.6 1.7 2 0 0 2 2 2 0 Spindle pole body formation-associated protein RabGAP-TBC PF00566.18 CEP14107.1 - 4.8e-45 153.9 0.2 1.2e-44 152.6 0.2 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CEP14107.1 - 8e-27 93.4 0.2 4.6e-14 52.3 0.3 2.5 2 0 0 2 2 2 2 GRAM domain SgrT PF15894.5 CEP14107.1 - 0.061 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT EF-hand_6 PF13405.6 CEP14107.1 - 0.08 12.9 0.2 0.41 10.7 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain Dcc1 PF09724.9 CEP14108.1 - 1.1e-79 268.2 0.2 1.3e-79 268.0 0.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 AF-4 PF05110.13 CEP14109.1 - 0.0038 15.4 10.5 0.0048 15.1 10.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein IMUP PF15761.5 CEP14109.1 - 0.0087 16.7 8.1 0.0087 16.7 8.1 2.1 2 0 0 2 2 2 1 Immortalisation up-regulated protein Spt20 PF12090.8 CEP14109.1 - 0.014 15.0 11.4 0.014 15.0 11.4 1.8 2 0 0 2 2 2 0 Spt20 family Pox_C7_F8A PF03287.14 CEP14109.1 - 0.047 13.7 0.2 0.084 12.9 0.2 1.4 1 0 0 1 1 1 0 Poxvirus C7/F8A protein SR-25 PF10500.9 CEP14109.1 - 0.053 13.1 15.0 0.055 13.1 10.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2681 PF10883.8 CEP14109.1 - 0.096 13.1 12.1 0.43 11.0 4.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Mem_trans PF03547.18 CEP14109.1 - 0.23 9.8 0.5 0.27 9.6 0.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Sec20 PF03908.13 CEP14109.1 - 0.4 10.6 6.5 0.27 11.2 3.7 2.1 2 0 0 2 2 2 0 Sec20 EMC3_TMCO1 PF01956.16 CEP14109.1 - 1.5 8.5 5.8 0.64 9.7 1.7 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DivIC PF04977.15 CEP14109.1 - 2.6 7.9 14.4 1.1 9.1 7.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Androgen_recep PF02166.16 CEP14109.1 - 4.5 6.0 13.2 6.6 5.4 13.2 1.2 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 CEP14109.1 - 5.4 5.7 5.8 6.7 5.4 5.8 1.2 1 0 0 1 1 1 0 Presenilin Sina PF03145.16 CEP14110.1 - 1.4e-06 28.4 14.0 0.0019 18.2 3.6 2.9 1 1 1 2 2 2 2 Seven in absentia protein family zf-RING_6 PF14835.6 CEP14110.1 - 7.8e-06 25.7 4.4 2.3e-05 24.2 4.4 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CEP14110.1 - 8.4e-05 22.3 16.2 8.4e-05 22.3 16.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP14110.1 - 0.0003 20.9 11.6 0.0003 20.9 11.6 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CEP14110.1 - 0.00076 19.3 12.4 0.0023 17.7 12.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP14110.1 - 0.0011 18.7 16.6 0.0047 16.8 16.6 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP14110.1 - 0.0018 18.5 15.0 0.0018 18.5 15.0 2.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP14110.1 - 0.048 13.7 11.3 0.044 13.8 8.4 2.6 1 1 1 2 2 2 0 RING-type zinc-finger Ion_trans PF00520.31 CEP14111.1 - 0.0013 18.0 2.9 0.0017 17.6 2.9 1.2 1 0 0 1 1 1 1 Ion transport protein TSC22 PF01166.18 CEP14111.1 - 0.0049 17.1 2.7 0.0081 16.5 2.7 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family 60KD_IMP PF02096.20 CEP14111.1 - 0.014 15.3 2.1 0.026 14.4 1.0 1.8 2 0 0 2 2 2 0 60Kd inner membrane protein PH PF00169.29 CEP14112.1 - 1.8e-08 34.8 1.7 3.1e-08 34.0 1.7 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CEP14112.1 - 8.1e-08 32.6 1.1 8.1e-08 32.6 1.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 CEP14112.1 - 0.051 14.0 0.6 0.13 12.6 0.6 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain DGF-1_C PF11040.8 CEP14112.1 - 0.083 12.9 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Fasciclin PF02469.22 CEP14113.1 - 7.6e-52 174.9 0.1 9.9e-16 58.1 0.1 5.2 5 0 0 5 5 5 5 Fasciclin domain PPP5 PF08321.12 CEP14114.1 - 2.4e-30 104.7 2.1 2.8e-29 101.2 0.3 2.5 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 CEP14114.1 - 2.6e-29 103.2 0.4 4.3e-29 102.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 CEP14114.1 - 5.7e-14 51.3 6.5 0.00025 20.7 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP14114.1 - 4.6e-11 42.0 6.5 0.0023 17.9 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP14114.1 - 3.2e-09 36.3 0.2 1.4e-05 24.6 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 CEP14114.1 - 2e-06 27.5 5.5 0.68 10.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEP14114.1 - 4e-05 23.7 0.0 0.00041 20.4 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP14114.1 - 8.2e-05 23.0 0.1 0.0033 17.9 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP14114.1 - 0.00013 22.0 3.3 0.54 10.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP14114.1 - 0.0012 19.5 0.0 0.034 15.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP14114.1 - 0.0021 18.3 0.6 1 9.7 0.1 2.9 2 2 0 2 2 2 1 Tetratricopeptide repeat UvrD-helicase PF00580.21 CEP14114.1 - 0.015 14.9 0.2 0.017 14.7 0.2 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SHNi-TPR PF10516.9 CEP14114.1 - 0.016 14.7 0.1 4.4 6.9 0.0 2.7 3 0 0 3 3 3 0 SHNi-TPR TPR_16 PF13432.6 CEP14114.1 - 0.032 14.9 0.0 13 6.5 0.0 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CEP14114.1 - 0.077 13.1 0.1 18 5.5 0.0 2.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CEP14114.1 - 0.1 12.7 0.1 19 5.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CEP14114.1 - 0.12 12.5 5.7 1.8 8.7 1.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain La PF05383.17 CEP14115.1 - 4.2e-19 68.4 0.5 7.6e-19 67.5 0.5 1.5 1 0 0 1 1 1 1 La domain Nuc_sug_transp PF04142.15 CEP14116.1 - 2.7e-114 381.6 10.9 3e-114 381.4 10.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CEP14116.1 - 4.8e-09 36.5 25.1 4.6e-06 26.8 2.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 CEP14116.1 - 0.0014 18.2 1.0 0.0014 18.2 1.0 2.1 1 1 0 2 2 2 1 Putative multidrug resistance efflux transporter W2 PF02020.18 CEP14118.1 - 0.0024 18.0 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF5470 PF17564.2 CEP14120.1 - 1.5 9.1 8.8 4.4 7.6 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5470) DUF4054 PF13262.6 CEP14121.1 - 5.4 7.1 7.3 2.8 8.0 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) Cellulase PF00150.18 CEP14123.1 - 1.4e-15 57.5 0.6 4.2e-11 42.8 0.0 3.7 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_1 PF00232.18 CEP14123.1 - 0.031 12.7 0.0 0.064 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF4854 PF16146.5 CEP14123.1 - 0.068 13.5 0.2 0.41 11.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Glyco_hydro_35 PF01301.19 CEP14123.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF2458 PF10454.9 CEP14124.1 - 1.2e-06 28.2 8.3 1.2e-06 28.2 8.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 CEP14124.1 - 4e-05 23.3 13.0 0.0002 21.1 13.0 1.9 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein EutB PF06751.11 CEP14124.1 - 0.015 14.1 0.3 0.022 13.6 0.3 1.3 1 1 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) ExbD PF02472.16 CEP14124.1 - 0.035 14.3 1.4 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR pP_pnuc_1 PF18165.1 CEP14124.1 - 0.091 12.6 3.7 0.15 11.9 3.7 1.4 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease Consortin_C PF15281.6 CEP14124.1 - 0.11 12.6 1.6 0.22 11.5 1.6 1.5 1 0 0 1 1 1 0 Consortin C-terminus NAM-associated PF14303.6 CEP14124.1 - 0.95 10.2 16.1 2 9.1 16.1 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Ly49 PF08391.10 CEP14124.1 - 6.6 7.1 9.2 2.7 8.4 5.8 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region CRF PF00473.17 CEP14125.1 - 2.7 8.1 5.2 10 6.3 2.4 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family Ndc1_Nup PF09531.10 CEP14126.1 - 0.0063 15.3 2.5 0.0076 15.0 2.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup AMP-binding PF00501.28 CEP14131.1 - 7.8e-100 334.4 0.0 1e-99 334.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP14131.1 - 0.0013 19.7 0.1 0.004 18.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KLRAQ PF10205.9 CEP14132.1 - 8.8e-18 64.4 11.5 8.8e-18 64.4 11.5 6.5 3 3 2 5 5 5 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 CEP14132.1 - 1.3e-16 60.8 7.3 1.3e-16 60.8 7.3 3.8 2 1 3 5 5 5 1 Predicted coiled-coil domain-containing protein Mobilization_B PF17511.2 CEP14132.1 - 1.1 9.7 6.0 0.75 10.2 2.6 2.6 1 1 0 1 1 1 0 Mobilization protein B Utp14 PF04615.13 CEP14133.1 - 4.9e-202 673.5 96.9 4.9e-202 673.5 96.9 2.0 1 1 1 2 2 2 1 Utp14 protein Lipase_3 PF01764.25 CEP14134.1 - 6.4e-18 65.0 0.0 5.2e-17 62.0 0.0 2.6 2 1 0 2 2 2 1 Lipase (class 3) NIF PF03031.18 CEP14134.1 - 1.7e-11 44.1 0.0 4.4e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AAA_18 PF13238.6 CEP14134.1 - 2.9 8.5 4.9 1.2 9.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.6 CEP14135.1 - 2.7e-72 238.8 18.1 5.6e-11 42.5 0.1 17.4 15 3 5 20 20 19 15 PPR repeat family PPR PF01535.20 CEP14135.1 - 2.1e-48 159.2 21.4 3.8e-05 23.6 0.0 18.7 23 0 0 23 23 22 10 PPR repeat PPR_3 PF13812.6 CEP14135.1 - 1.7e-42 143.4 12.4 5.6e-05 23.1 0.1 14.1 12 1 4 16 16 16 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP14135.1 - 5.4e-42 141.2 0.1 6.2e-06 25.8 0.0 13.9 15 0 0 15 15 15 7 PPR repeat PPR_long PF17177.4 CEP14135.1 - 2.6e-33 115.2 21.5 2.8e-07 30.1 0.1 8.7 4 2 3 9 9 9 7 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CEP14135.1 - 1.2e-06 28.9 18.1 0.24 11.9 0.2 8.7 9 1 2 11 11 10 2 Tetratricopeptide repeat ATP13 PF12921.7 CEP14135.1 - 5.7e-06 26.2 5.9 4.7 7.1 0.0 6.7 5 2 1 6 6 6 2 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 CEP14135.1 - 8.6e-06 25.8 7.7 8.5 6.3 0.1 7.1 4 3 4 8 8 8 1 Virulence factor membrane-bound polymerase, C-terminal RPM2 PF08579.11 CEP14135.1 - 0.0096 16.3 0.5 0.0096 16.3 0.5 5.8 6 1 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) Paramyxo_P_V_N PF13825.6 CEP14135.1 - 0.035 13.5 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Exog_C PF18026.1 CEP14135.1 - 0.038 14.0 0.1 2.1 8.4 0.0 3.4 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain TPR_8 PF13181.6 CEP14135.1 - 0.044 14.0 5.0 4 7.9 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat UMPH-1 PF05822.12 CEP14137.1 - 3.5e-81 272.4 1.5 4.1e-81 272.1 1.5 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 CEP14137.1 - 8.7e-05 23.0 0.0 0.00015 22.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP14137.1 - 0.072 13.2 0.6 0.85 9.7 0.2 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SPATA19 PF15212.6 CEP14137.1 - 0.12 12.6 0.5 1.1 9.5 0.1 2.4 2 1 1 3 3 3 0 Spermatogenesis-associated protein 19, mitochondrial YodL PF14191.6 CEP14138.1 - 0.062 14.2 0.0 0.2 12.5 0.0 1.9 1 0 0 1 1 1 0 YodL-like DDA1 PF10172.9 CEP14138.1 - 0.27 11.5 1.8 1 9.7 0.0 2.8 3 0 0 3 3 3 0 Det1 complexing ubiquitin ligase RVT_1 PF00078.27 CEP14139.1 - 1.2e-15 57.7 0.1 1.5e-12 47.5 0.1 2.7 3 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3808 PF10300.9 CEP14140.1 - 3.3e-89 299.8 10.1 8e-89 298.5 10.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Tudor_FRX1 PF18336.1 CEP14140.1 - 0.14 12.1 0.8 0.97 9.4 0.2 2.6 3 0 0 3 3 3 0 Fragile X mental retardation Tudor domain ANAPC3 PF12895.7 CEP14140.1 - 0.51 10.6 7.0 3.9 7.8 0.9 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RGS PF00615.19 CEP14141.1 - 3e-22 79.1 0.0 9.7e-21 74.2 0.0 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 CEP14141.1 - 4.7e-12 45.8 0.2 4.4e-06 26.7 0.2 3.5 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Rop PF01815.16 CEP14141.1 - 0.082 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Rop protein RNA_pol_3_Rpc31 PF11705.8 CEP14141.1 - 4 7.6 11.9 2.9 8.1 1.0 3.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Chitin_synth_1 PF01644.17 CEP14142.1 - 2.8e-77 258.3 0.4 4.5e-77 257.6 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEP14142.1 - 2.2e-28 98.0 0.3 7e-28 96.4 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEP14142.1 - 1.6e-18 66.6 0.0 2.8e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP14142.1 - 2.4e-06 27.6 0.1 6.9e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Arm PF00514.23 CEP14143.1 - 1.5e-06 28.0 10.3 0.5 10.5 0.0 8.3 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Casein_kappa PF00997.18 CEP14143.1 - 0.17 12.0 1.3 0.3 11.2 1.3 1.3 1 0 0 1 1 1 0 Kappa casein HEAT_2 PF13646.6 CEP14143.1 - 0.25 11.8 2.0 37 4.8 0.0 4.1 3 2 1 4 4 4 0 HEAT repeats EF-G-binding_N PF07299.11 CEP14143.1 - 0.41 11.2 7.4 14 6.3 0.0 4.6 5 0 0 5 5 5 0 Elongation factor G-binding protein, N-terminal Atx10homo_assoc PF09759.9 CEP14143.1 - 1.6 8.8 11.3 8.7 6.4 0.0 4.8 4 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CBFB_NFYA PF02045.15 CEP14145.1 - 7.1e-29 100.2 7.0 7.1e-29 100.2 7.0 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Spt20 PF12090.8 CEP14145.1 - 0.15 11.6 12.1 0.19 11.3 12.1 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CEP14145.1 - 0.38 10.7 17.3 0.44 10.5 17.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIS_M PF07500.14 CEP14146.1 - 1e-25 90.4 0.3 1e-25 90.4 0.3 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CEP14146.1 - 3.3e-20 71.7 5.7 5.3e-20 71.0 5.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CEP14146.1 - 1.3e-11 44.3 3.5 1.3e-11 44.3 3.5 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.8 CEP14146.1 - 8.2e-05 22.2 0.8 0.00018 21.1 0.8 1.7 1 1 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Pex14_N PF04695.13 CEP14146.1 - 0.01 16.5 1.5 0.019 15.6 1.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Terminase_2 PF03592.16 CEP14146.1 - 0.04 14.4 3.3 0.19 12.2 3.3 2.0 1 1 0 1 1 1 0 Terminase small subunit DUF2854 PF11016.8 CEP14147.1 - 0.083 12.8 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) DPBB_1 PF03330.18 CEP14148.1 - 3.4e-11 43.2 0.1 1.5e-10 41.2 0.1 2.1 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEP14148.1 - 0.0015 18.4 0.8 0.004 17.0 0.2 1.8 1 1 1 2 2 2 1 Barwin family Peptidase_M41 PF01434.18 CEP14149.1 - 3e-64 216.4 0.0 4.6e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CEP14149.1 - 3.4e-43 147.2 0.0 7.2e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP14149.1 - 2.4e-12 46.4 0.2 9.4e-12 44.5 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 CEP14149.1 - 3.1e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CEP14149.1 - 0.0012 18.9 0.1 0.01 15.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP14149.1 - 0.0018 18.7 0.2 0.061 13.7 0.2 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEP14149.1 - 0.0021 18.4 0.0 0.54 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CEP14149.1 - 0.0029 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CEP14149.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 CEP14149.1 - 0.0054 17.1 0.4 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CEP14149.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CEP14149.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEP14149.1 - 0.17 11.2 0.2 0.37 10.2 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CEP14149.1 - 0.19 11.9 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 CEP14150.1 - 8.1e-25 87.4 0.1 3.9e-24 85.2 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP14150.1 - 3.4e-15 56.3 0.0 1.9e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CEP14150.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CEP14150.1 - 6.8e-06 26.1 0.0 9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_9 PF00759.19 CEP14151.1 - 1.3e-91 308.0 4.5 5.3e-91 306.1 4.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 VPDSG-CTERM PF18205.1 CEP14151.1 - 4.5 7.2 8.7 0.091 12.6 1.5 2.0 2 0 0 2 2 2 0 VPDSG-CTERM motif LIM PF00412.22 CEP14152.1 - 3.6e-50 168.0 42.6 1.1e-15 57.6 5.3 4.5 4 0 0 4 4 4 4 LIM domain RVT_1 PF00078.27 CEP14152.1 - 3.9e-13 49.4 0.0 9.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP14152.1 - 3.9e-05 24.3 1.2 3.9e-05 24.3 1.2 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DDE_3 PF13358.6 CEP14155.1 - 2.5e-05 24.0 0.0 6.2e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP14155.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 CEP14155.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DAHP_snth_FXD PF18152.1 CEP14155.1 - 0.24 11.2 2.6 16 5.4 0.1 3.5 3 1 1 4 4 4 0 DAHP synthase ferredoxin-like domain Ribosomal_L26 PF16906.5 CEP14157.1 - 8e-35 119.2 4.3 8e-35 119.2 4.3 2.3 2 0 0 2 2 2 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CEP14157.1 - 2e-09 37.0 3.7 5.3e-09 35.7 3.7 1.7 1 0 0 1 1 1 1 KOW motif TFIIF_alpha PF05793.12 CEP14157.1 - 1.9e-06 26.8 74.8 0.021 13.4 0.9 3.4 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1442 PF07279.11 CEP14157.1 - 0.16 11.3 1.4 0.27 10.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PAS_3 PF08447.12 CEP14158.1 - 9.2e-14 51.5 0.0 1e-10 41.8 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CEP14158.1 - 3.9e-07 30.3 0.1 0.00055 20.2 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CEP14158.1 - 3.3e-06 27.1 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CEP14158.1 - 0.00029 20.9 0.1 0.0061 16.7 0.0 2.4 2 0 0 2 2 2 1 PAS domain sCache_2 PF17200.4 CEP14158.1 - 0.0042 16.9 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Single Cache domain 2 DUF1749 PF08538.10 CEP14159.1 - 4.2e-58 196.8 0.1 5.1e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.12 CEP14159.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 CEP14159.1 - 0.034 13.4 0.0 0.13 11.5 0.0 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CEP14159.1 - 0.053 13.1 0.1 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF915 PF06028.11 CEP14159.1 - 0.054 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF423 PF04241.15 CEP14160.1 - 9.3e-15 54.6 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Pkinase PF00069.25 CEP14161.1 - 5.7e-75 252.1 0.0 7.4e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14161.1 - 2.4e-28 99.1 0.0 1.5e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP14161.1 - 1.9e-10 40.6 1.0 0.011 15.1 0.0 3.1 2 1 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 CEP14161.1 - 0.0005 19.0 0.0 0.00083 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEP14161.1 - 0.0012 18.8 0.1 0.51 10.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CEP14161.1 - 0.023 14.3 0.0 1.7 8.2 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CEP14161.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDC10_II PF16787.5 CEP14162.1 - 1.3e-12 47.4 0.1 8.8e-12 44.7 0.1 1.9 1 1 1 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 SlyX PF04102.12 CEP14163.1 - 0.024 15.3 0.2 1.1 10.0 0.2 2.3 1 1 0 1 1 1 0 SlyX HTH_Tnp_Tc3_2 PF01498.18 CEP14164.1 - 7.4e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CEP14164.1 - 3.1e-07 30.2 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP14164.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP14164.1 - 0.0017 18.1 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_1 PF11427.8 CEP14164.1 - 0.047 13.6 1.1 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 Tc3 transposase Cactin_mid PF10312.9 CEP14165.1 - 0.0015 18.3 1.0 0.0016 18.2 1.0 1.0 1 0 0 1 1 1 1 Conserved mid region of cactin Condensation PF00668.20 CEP14165.1 - 0.0088 14.8 0.7 0.01 14.5 0.7 1.0 1 0 0 1 1 1 1 Condensation domain Mistic PF11458.8 CEP14165.1 - 0.013 15.4 4.5 0.34 10.9 0.1 2.1 1 1 1 2 2 2 0 Membrane-integrating protein Mistic DUF2098 PF09871.9 CEP14165.1 - 0.066 13.6 2.7 0.085 13.2 2.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) PIF1 PF05970.14 CEP14166.1 - 2.7e-14 53.2 0.0 3.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase GATA PF00320.27 CEP14167.1 - 7.3e-11 41.5 14.1 1.1e-09 37.8 2.8 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP14167.1 - 3.4 7.2 10.1 0.46 10.1 0.3 2.8 2 1 1 3 3 3 0 TFIIB zinc-binding Ctf8 PF09696.10 CEP14168.1 - 1.1e-10 42.0 0.2 4.5e-10 40.0 0.1 1.9 1 1 1 2 2 2 1 Ctf8 Lig_chan-Glu_bd PF10613.9 CEP14168.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site DUF3909 PF13077.6 CEP14168.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) Vps54 PF07928.12 CEP14169.1 - 8.3e-51 171.9 2.8 8.3e-51 171.9 2.8 2.1 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 CEP14169.1 - 4.5e-10 39.3 1.2 4.5e-10 39.3 1.2 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CEP14169.1 - 3.6e-05 23.7 2.5 0.00016 21.5 1.3 2.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) LOH1CR12 PF10158.9 CEP14169.1 - 3 7.9 6.1 12 5.9 0.2 3.0 2 0 0 2 2 2 0 Tumour suppressor protein PSP1 PF04468.12 CEP14170.1 - 4.7e-33 113.3 2.0 4.7e-33 113.3 2.0 2.3 2 0 0 2 2 2 1 PSP1 C-terminal conserved region UPF0524 PF15823.5 CEP14170.1 - 0.44 9.9 10.4 0.025 14.0 2.5 2.3 2 0 0 2 2 2 0 UPF0524 of C3orf70 PepSY_TM PF03929.16 CEP14170.1 - 0.79 9.3 2.8 1 8.9 0.3 2.2 2 0 0 2 2 2 0 PepSY-associated TM region SIR2 PF02146.17 CEP14171.1 - 2.7e-31 108.9 0.0 3.5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF547 PF04784.14 CEP14171.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 JmjC PF02373.22 CEP14172.1 - 9.8e-42 142.0 0.8 4e-41 140.0 0.8 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase PLU-1 PF08429.11 CEP14172.1 - 1.9e-28 99.7 10.9 5e-26 91.7 6.6 2.3 2 0 0 2 2 2 2 PLU-1-like protein ARID PF01388.21 CEP14172.1 - 9.3e-20 71.1 0.0 2.4e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CEP14172.1 - 1.2e-19 69.9 28.2 6.2e-13 48.4 5.8 3.1 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 CEP14172.1 - 3.5e-17 62.1 4.2 1.8e-16 59.8 4.3 2.2 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 CEP14172.1 - 3.6e-12 46.5 12.7 3.6e-12 46.5 12.7 3.2 2 0 0 2 2 2 1 C5HC2 zinc finger zf-PHD-like PF15446.6 CEP14172.1 - 0.0096 15.6 10.2 0.029 14.0 1.4 2.9 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Ndufs5 PF10200.9 CEP14172.1 - 0.013 15.8 1.3 0.55 10.5 0.6 3.2 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa zf-HC5HC2H_2 PF13832.6 CEP14172.1 - 0.66 10.2 25.8 0.041 14.1 2.5 3.8 3 1 0 3 3 3 0 PHD-zinc-finger like domain SR-25 PF10500.9 CEP14172.1 - 4 7.0 20.0 0.41 10.2 15.1 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein E2F_TDP PF02319.20 CEP14173.1 - 5.3e-25 87.3 0.2 1.4e-24 85.9 0.2 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 CEP14173.1 - 4.6e-07 30.1 2.3 1.3e-06 28.7 2.3 1.8 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain Wtap PF17098.5 CEP14173.1 - 0.011 15.6 1.0 0.011 15.6 1.0 2.5 3 0 0 3 3 3 0 WTAP/Mum2p family TrmB PF01978.19 CEP14173.1 - 0.013 15.4 0.1 0.47 10.4 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB baeRF_family8 PF18851.1 CEP14173.1 - 0.028 14.5 0.1 0.028 14.5 0.1 1.9 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 8 DUF4107 PF13389.6 CEP14173.1 - 0.09 12.9 1.7 0.24 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) FPP PF05911.11 CEP14173.1 - 0.2 9.8 14.3 0.24 9.6 14.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 CEP14173.1 - 1 9.5 11.5 0.16 12.2 1.5 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 CEP14173.1 - 5.8 7.1 6.8 0.35 11.0 0.7 2.3 3 0 0 3 3 3 0 bZIP transcription factor RCC1 PF00415.18 CEP14175.1 - 1.2e-48 163.4 7.9 2.7e-11 43.9 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEP14175.1 - 2.6e-27 94.0 26.2 2.6e-06 27.1 0.0 7.9 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CEP14175.1 - 0.006 16.3 0.0 3.2 7.4 0.0 3.0 3 0 0 3 3 3 2 TUP1-like enhancer of split Peptidase_M49 PF03571.15 CEP14176.1 - 1e-07 30.8 0.1 7.3e-06 24.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M49 MPTase-PolyVal PF18818.1 CEP14176.1 - 0.00065 19.7 1.8 0.0013 18.8 0.1 2.3 3 0 0 3 3 3 1 Metallopeptidase superfamily domain ALS_ss_C PF10369.9 CEP14176.1 - 0.2 11.9 0.0 22 5.4 0.0 2.5 2 0 0 2 2 2 0 Small subunit of acetolactate synthase Pkinase PF00069.25 CEP14178.1 - 2e-76 256.9 0.0 2.6e-76 256.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14178.1 - 6.1e-39 133.9 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP14178.1 - 2.8e-07 30.1 0.0 0.00027 20.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CEP14178.1 - 1.8e-05 24.8 0.1 0.23 11.3 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CEP14178.1 - 2.4e-05 24.0 1.6 0.00015 21.4 0.1 2.2 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 CEP14178.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP14178.1 - 0.0014 17.6 0.0 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CEP14178.1 - 0.027 14.0 0.2 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 CEP14178.1 - 0.028 13.4 0.4 0.028 13.4 0.4 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Mito_carr PF00153.27 CEP14179.1 - 4.5e-61 202.8 5.7 5.3e-21 74.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP14179.1 - 0.0061 15.7 3.2 0.14 11.2 0.0 3.1 3 1 0 4 4 4 2 Gammaproteobacterial serine protease Xpo1 PF08389.12 CEP14180.1 - 2.2e-05 24.6 0.5 0.00087 19.4 0.0 3.6 3 0 0 3 3 3 1 Exportin 1-like protein TPR_1 PF00515.28 CEP14181.1 - 1.4e-53 176.6 36.1 5e-08 32.4 0.1 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP14181.1 - 2.7e-48 158.2 30.6 3.2e-06 26.8 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEP14181.1 - 6.3e-33 110.2 28.4 7.4e-06 25.8 0.0 10.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 CEP14181.1 - 7.2e-26 88.7 16.4 0.00028 21.4 0.0 9.1 3 2 7 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEP14181.1 - 8.1e-25 87.2 13.4 4.8e-05 23.9 0.9 6.9 3 3 2 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 CEP14181.1 - 1.5e-24 86.3 15.5 4.6e-05 23.8 0.1 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CEP14181.1 - 3.2e-24 85.0 25.3 2e-05 24.8 0.8 7.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CEP14181.1 - 6.2e-24 83.4 34.8 3.7e-05 23.3 1.5 9.5 4 2 5 9 9 9 7 TPR repeat TPR_17 PF13431.6 CEP14181.1 - 1.3e-23 81.6 27.5 0.00062 20.0 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 CEP14181.1 - 2.4e-19 67.9 19.8 0.024 14.7 0.1 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 CEP14181.1 - 1.1e-18 67.1 12.6 0.00042 20.4 0.2 6.7 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 CEP14181.1 - 1.7e-18 66.0 25.4 0.0015 19.0 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP14181.1 - 5.8e-10 39.3 16.4 3.2e-07 30.5 2.2 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEP14181.1 - 2e-09 37.1 16.5 0.018 14.3 0.1 5.5 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_21 PF09976.9 CEP14181.1 - 3.8e-05 23.5 10.0 0.019 14.7 0.9 4.6 4 2 0 4 4 4 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 CEP14181.1 - 0.002 17.9 8.1 0.56 9.9 0.2 3.1 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 CEP14181.1 - 0.0032 17.3 17.2 3.4 7.7 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEP14181.1 - 0.0041 17.4 0.4 9.8 6.6 0.0 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 CEP14181.1 - 0.012 15.1 20.0 0.92 8.9 2.5 4.7 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 CEP14181.1 - 0.04 12.9 5.1 2.9 6.8 1.1 2.8 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 CEP14181.1 - 0.042 14.3 11.9 6.4 7.2 0.1 3.7 3 1 0 3 3 3 0 Bacterial transcriptional activator domain PGA_cap PF09587.10 CEP14181.1 - 0.062 12.7 0.1 0.21 11.0 0.1 1.8 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF1824 PF08854.10 CEP14181.1 - 0.26 11.2 1.5 1 9.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) DUF627 PF04781.12 CEP14181.1 - 0.57 10.2 2.4 26 4.9 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) MIT PF04212.18 CEP14181.1 - 1.7 8.7 26.8 3.7 7.7 0.5 7.0 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CEP14181.1 - 9.6 6.3 26.1 3.7 7.6 1.3 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1751 PF08551.10 CEP14182.1 - 1.4e-25 89.7 3.7 1.4e-25 89.7 3.7 1.6 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CEP14182.1 - 9.4e-08 32.2 1.3 1.6e-07 31.4 1.3 1.4 1 0 0 1 1 1 1 Rhomboid family FA_desaturase PF00487.24 CEP14182.1 - 0.061 13.2 0.7 0.073 12.9 0.7 1.1 1 0 0 1 1 1 0 Fatty acid desaturase PPR_2 PF13041.6 CEP14183.1 - 1.5e-13 50.7 12.3 0.00049 20.2 0.1 7.7 6 1 3 9 9 9 4 PPR repeat family PPR_3 PF13812.6 CEP14183.1 - 6.4e-13 48.6 5.1 0.0029 17.7 0.1 6.5 5 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 CEP14183.1 - 1.1e-06 28.5 2.1 1.3 9.5 0.1 7.4 8 0 0 8 8 8 1 PPR repeat PPR_long PF17177.4 CEP14183.1 - 2.1e-05 24.0 9.1 0.74 9.1 0.0 5.4 3 2 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CEP14183.1 - 0.00041 20.8 0.2 1.1 9.9 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat Corona_M PF01635.18 CEP14183.1 - 0.0097 15.2 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 1 Coronavirus M matrix/glycoprotein PPR_1 PF12854.7 CEP14183.1 - 0.021 14.5 0.2 6.5 6.5 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Clathrin PF00637.20 CEP14183.1 - 0.029 14.2 0.3 15 5.4 0.0 3.5 4 0 0 4 4 4 0 Region in Clathrin and VPS Wzy_C_2 PF11846.8 CEP14183.1 - 0.057 13.3 0.2 0.71 9.8 0.0 2.7 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ATP13 PF12921.7 CEP14183.1 - 0.089 12.6 0.2 3.4 7.6 0.0 3.5 4 1 1 5 5 5 0 Mitochondrial ATPase expression ADH_N PF08240.12 CEP14185.1 - 3.4e-20 72.0 3.6 3.4e-20 72.0 3.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP14185.1 - 3.7e-16 59.3 0.0 5.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP14185.1 - 0.00013 23.1 0.0 0.00019 22.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEP14185.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATG16 PF08614.11 CEP14186.1 - 0.0002 21.7 2.5 0.0002 21.7 2.5 2.6 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) NRBF2 PF08961.10 CEP14186.1 - 0.0033 17.1 2.6 0.0033 17.1 2.6 3.2 2 1 1 3 3 3 1 Nuclear receptor-binding factor 2, autophagy regulator APG6_N PF17675.1 CEP14186.1 - 0.062 13.8 17.1 0.9 10.1 4.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FKS1_dom1 PF14288.6 CEP14186.1 - 0.32 11.3 4.8 0.36 11.2 0.2 2.5 2 1 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 UPF0242 PF06785.11 CEP14186.1 - 0.33 11.0 17.6 0.78 9.8 5.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AbiH PF14253.6 CEP14186.1 - 0.7 9.7 8.8 0.083 12.7 2.3 2.1 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Cut12 PF11500.8 CEP14186.1 - 1.6 8.7 10.0 0.085 12.8 3.8 2.0 2 1 1 3 3 3 0 Spindle pole body formation-associated protein FlaC_arch PF05377.11 CEP14186.1 - 1.7 9.1 11.3 5.4 7.5 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 CEP14186.1 - 2.1 9.3 24.5 2 9.4 2.0 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 CEP14186.1 - 2.9 8.6 23.3 1.6 9.4 2.2 3.9 2 2 1 3 3 3 0 Initiation control protein YabA Cas_DxTHG PF09455.10 CEP14186.1 - 3.8 7.0 10.5 10 5.6 10.5 1.6 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family bZIP_1 PF00170.21 CEP14186.1 - 3.9 7.6 20.6 0.36 11.0 1.6 4.1 3 2 2 5 5 5 0 bZIP transcription factor Rpn9_C PF18261.1 CEP14186.1 - 5.9 6.6 9.0 16 5.2 0.5 2.9 2 0 0 2 2 2 0 Rpn9 C-terminal helix LPP PF04728.13 CEP14186.1 - 6.7 7.2 9.2 5.1 7.6 0.3 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper EF-hand_4 PF12763.7 CEP14187.1 - 4.8e-26 90.7 0.0 2.6e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand RhoGEF PF00621.20 CEP14187.1 - 1.6e-21 77.4 0.5 1.6e-21 77.4 0.5 2.2 2 0 0 2 2 2 1 RhoGEF domain WH2 PF02205.20 CEP14187.1 - 3.8e-10 39.3 0.5 1.5e-09 37.3 0.5 2.2 1 0 0 1 1 1 1 WH2 motif CNH PF00780.22 CEP14187.1 - 5.1e-10 39.4 0.0 2.2e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 CNH domain EF-hand_7 PF13499.6 CEP14187.1 - 0.13 12.8 0.9 1.8 9.1 0.1 3.2 3 1 0 3 3 3 0 EF-hand domain pair NDC10_II PF16787.5 CEP14188.1 - 1.7e-13 50.4 0.0 1.8e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Polysacc_deac_1 PF01522.21 CEP14189.1 - 5.5e-29 100.6 0.0 7.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP14189.1 - 2e-08 33.8 0.0 1.8e-07 30.7 0.0 2.2 1 1 2 3 3 3 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CEP14189.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.21 CEP14190.1 - 1.7e-25 89.3 0.0 2.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP14190.1 - 3.6e-07 29.7 0.1 7.7e-07 28.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CEP14190.1 - 2.2e-05 24.2 0.5 5.1e-05 23.0 0.3 1.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) ANAPC2 PF08672.11 CEP14191.1 - 2.6 8.6 6.9 1.2 9.7 0.2 3.9 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 HLH PF00010.26 CEP14192.1 - 2.5e-13 49.8 1.9 6e-13 48.5 1.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Borealin PF10512.9 CEP14192.1 - 3.4 7.7 9.2 0.17 11.9 1.7 2.5 2 1 1 3 3 3 0 Cell division cycle-associated protein 8 NAD_binding_10 PF13460.6 CEP14195.1 - 3.2e-23 82.6 0.0 3.9e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP14195.1 - 0.00022 20.9 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family DUF211 PF02680.14 CEP14195.1 - 0.027 14.6 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 cobW PF02492.19 CEP14195.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Trypsin_2 PF13365.6 CEP14196.1 - 3.5e-12 47.4 0.0 5.7e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CEP14196.1 - 3.5e-07 30.3 1.0 1.8e-06 27.9 1.0 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S3 PF00944.19 CEP14196.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Porin_8 PF16966.5 CEP14197.1 - 0.058 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Porin-like glycoporin RafY Malic_M PF03949.15 CEP14199.1 - 3.9e-91 304.9 0.0 6e-91 304.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEP14199.1 - 4.4e-72 241.7 0.0 8.4e-72 240.8 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Aa_trans PF01490.18 CEP14200.1 - 9.4e-77 258.4 29.9 1.2e-76 258.1 29.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tim54 PF11711.8 CEP14201.1 - 1.8e-55 188.3 1.1 1.2e-42 146.1 0.4 2.0 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 HSP70 PF00012.20 CEP14201.1 - 0.0025 16.1 0.3 0.0032 15.7 0.3 1.2 1 0 0 1 1 1 1 Hsp70 protein Pkinase PF00069.25 CEP14202.1 - 3.9e-62 210.0 0.0 7.5e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14202.1 - 2.8e-33 115.3 0.0 6.4e-33 114.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DcpS_C PF11969.8 CEP14202.1 - 1.6e-23 83.4 0.3 1.3e-22 80.4 0.2 2.3 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CEP14202.1 - 2.5e-11 44.2 0.3 9.8e-11 42.3 0.3 2.0 1 0 0 1 1 1 1 HIT domain 4F5 PF04419.14 CEP14202.1 - 9.3e-05 23.2 10.1 0.00027 21.8 10.1 1.8 1 0 0 1 1 1 1 4F5 protein family Kinase-like PF14531.6 CEP14202.1 - 0.00039 19.8 1.6 0.45 9.8 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CEP14202.1 - 0.026 13.3 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CEP14202.1 - 0.036 13.7 0.8 0.14 11.8 0.8 1.9 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 CEP14202.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Retrotrans_gag PF03732.17 CEP14204.1 - 1.1e-05 25.6 0.4 5.5e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP14204.1 - 2.1e-05 25.1 0.0 4.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP14204.1 - 2.4e-05 24.1 0.1 5.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CEP14204.1 - 5.1e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4939 PF16297.5 CEP14204.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Peptidase_A2B PF12384.8 CEP14204.1 - 0.0018 17.8 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase Pex14_N PF04695.13 CEP14204.1 - 6.6 7.4 8.8 3.8 8.1 2.2 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Helitron_like_N PF14214.6 CEP14206.1 - 3.1e-16 60.2 0.8 1.5e-15 57.9 0.8 1.8 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phe_ZIP PF08916.11 CEP14206.1 - 0.017 15.8 0.5 0.031 15.0 0.5 1.4 1 0 0 1 1 1 0 Phenylalanine zipper 5_nucleotid PF05761.14 CEP14207.1 - 0.13 11.1 5.9 0.18 10.7 5.9 1.2 1 0 0 1 1 1 0 5' nucleotidase family TauD PF02668.16 CEP14208.1 - 4.3e-35 121.8 0.2 6.4e-35 121.2 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CEP14208.1 - 5.7e-20 71.8 0.4 1.2e-19 70.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 CEP14208.1 - 0.00066 18.9 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 CsiD AFG1_ATPase PF03969.16 CEP14208.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase NDC10_II PF16787.5 CEP14209.1 - 0.0056 15.8 0.2 0.24 10.4 0.0 2.2 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Copper-fist PF00649.18 CEP14212.1 - 2.5e-11 42.9 2.3 6.7e-11 41.5 2.3 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Arg_repressor PF01316.21 CEP14212.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain SPX PF03105.19 CEP14213.1 - 9.6e-36 124.5 4.0 8.5e-23 81.9 0.4 2.3 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 CEP14213.1 - 1.1e-31 110.2 26.7 8.8e-18 64.5 15.8 2.6 2 1 1 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 CEP14213.1 - 7.1e-29 101.2 33.8 9.9e-29 100.7 33.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Thaumatin PF00314.17 CEP14215.1 - 2.1e-46 158.3 17.0 9.6e-46 156.1 17.0 1.8 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CEP14215.1 - 0.026 13.8 2.7 1.3 8.3 0.0 2.6 2 1 1 3 3 3 0 Beta-1,3-glucanase OrfB_Zn_ribbon PF07282.11 CEP14216.1 - 2.3e-10 40.2 0.1 4.8e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain NMD3 PF04981.13 CEP14216.1 - 0.12 11.9 0.3 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 NMD3 family bZIP_1 PF00170.21 CEP14217.1 - 9.5e-07 28.8 4.6 9.5e-07 28.8 4.6 2.9 2 1 1 3 3 3 2 bZIP transcription factor SOGA PF11365.8 CEP14217.1 - 7.9e-05 23.7 10.5 0.0016 19.5 0.7 2.6 2 0 0 2 2 2 2 Protein SOGA bZIP_2 PF07716.15 CEP14217.1 - 0.002 18.1 6.8 0.002 18.1 6.8 3.8 2 1 2 4 4 4 2 Basic region leucine zipper YabA PF06156.13 CEP14217.1 - 0.015 15.9 4.8 0.015 15.9 4.8 2.5 2 0 0 2 2 2 0 Initiation control protein YabA NINJA_B PF16136.5 CEP14217.1 - 0.15 12.4 3.8 0.22 11.9 0.0 2.6 2 0 0 2 2 2 0 Putative nuclear localisation signal DUF3037 PF11236.8 CEP14217.1 - 0.72 10.3 3.8 0.42 11.0 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Macoilin PF09726.9 CEP14217.1 - 3.7 6.0 19.0 9.6 4.6 19.0 1.6 1 1 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 CEP14217.1 - 5 7.7 33.6 13 6.4 14.8 3.3 2 1 0 2 2 2 0 bZIP Maf transcription factor AAA_23 PF13476.6 CEP14217.1 - 5.6 7.4 18.4 1.7 9.1 4.5 2.2 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 CEP14217.1 - 9.8 6.2 25.9 0.92 9.6 5.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PH PF00169.29 CEP14218.1 - 6.9e-19 68.3 0.6 6.9e-19 68.3 0.6 2.5 3 0 0 3 3 3 1 PH domain SH3_9 PF14604.6 CEP14218.1 - 8.9e-14 51.1 2.6 9.7e-14 51.0 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 CEP14218.1 - 6.4e-13 48.1 0.4 6.4e-13 48.1 0.4 2.5 3 0 0 3 3 2 1 SH3 domain SAM_2 PF07647.17 CEP14218.1 - 7.7e-13 48.4 0.5 5.2e-11 42.5 0.0 2.6 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CEP14218.1 - 8.9e-10 38.1 0.2 1.9e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CEP14218.1 - 2.1e-07 31.2 0.1 5e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 CEP14218.1 - 0.00012 22.4 10.8 0.00069 20.0 5.3 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain SAM_PNT PF02198.16 CEP14218.1 - 0.0039 17.1 1.4 0.049 13.6 0.0 2.8 2 1 1 3 3 3 1 Sterile alpha motif (SAM)/Pointed domain PH_8 PF15409.6 CEP14218.1 - 0.0097 16.2 1.1 0.077 13.3 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_Ste50p PF09235.10 CEP14218.1 - 0.015 15.5 0.2 6.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Ste50p, sterile alpha motif NOA36 PF06524.12 CEP14218.1 - 5.1 6.3 12.7 9.4 5.5 12.7 1.4 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 CEP14218.1 - 7.4 6.2 10.7 18 4.9 10.7 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FliC_SP PF12613.8 CEP14219.1 - 0.19 12.3 4.2 0.24 11.9 4.2 1.2 1 0 0 1 1 1 0 Flagellin structural protein Bactofilin PF04519.13 CEP14220.1 - 0.029 14.7 0.1 0.55 10.6 0.1 2.1 2 0 0 2 2 2 0 Polymer-forming cytoskeletal DUF3575 PF12099.8 CEP14220.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3575) Kinesin PF00225.23 CEP14221.1 - 5.6e-92 308.2 0.3 5.6e-92 308.2 0.3 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP14221.1 - 8.6e-18 64.7 1.1 2.6e-15 56.7 0.0 3.5 3 0 0 3 3 3 2 Microtubule binding NOA36 PF06524.12 CEP14221.1 - 0.26 10.6 9.3 0.53 9.6 9.3 1.4 1 0 0 1 1 1 0 NOA36 protein DER1 PF04511.15 CEP14222.1 - 1.6e-45 155.4 6.0 1.8e-45 155.2 6.0 1.0 1 0 0 1 1 1 1 Der1-like family TMEM171 PF15471.6 CEP14222.1 - 0.035 13.1 0.1 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Cytochrom_C1 PF02167.15 CEP14223.1 - 6.9e-99 330.0 0.0 8.6e-99 329.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CEP14223.1 - 0.002 18.4 0.1 0.0042 17.4 0.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CEP14223.1 - 0.052 14.7 0.2 0.14 13.3 0.2 1.9 1 1 0 1 1 1 0 Cytochrome c PIP5K PF01504.18 CEP14224.1 - 1.4e-96 323.0 0.8 2.5e-96 322.1 0.8 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Helitron_like_N PF14214.6 CEP14226.1 - 1.8e-07 31.5 0.2 5.2e-07 30.1 0.2 1.7 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus MATalpha_HMGbox PF04769.12 CEP14226.1 - 0.018 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box GFA PF04828.14 CEP14228.1 - 1.7e-09 37.8 0.2 1.7e-09 37.8 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 CEP14228.1 - 0.019 14.8 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_ribbon_SprT PF17283.2 CEP14228.1 - 1.7 8.6 11.7 5.5 7.0 4.9 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Peptidase_M28 PF04389.17 CEP14229.1 - 8.9e-37 126.7 0.1 1.4e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CEP14229.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 TPPK_C PF12555.8 CEP14229.1 - 1.1 9.3 5.1 31 4.7 0.2 3.5 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Acyl-CoA_dh_N PF02771.16 CEP14230.1 - 3.2e-38 130.8 0.0 4.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEP14230.1 - 1.2e-26 92.8 0.0 1.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP14231.1 - 2.1e-42 144.9 0.0 2.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP14231.1 - 1e-14 55.0 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SIR2 PF02146.17 CEP14233.1 - 2.9e-36 125.0 0.0 4.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CEP14233.1 - 0.0021 17.8 0.0 0.92 9.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain AsmA_1 PF13109.6 CEP14233.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region Zn-ribbon_8 PF09723.10 CEP14233.1 - 0.17 12.0 1.4 0.38 10.9 1.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Myb_DNA-bind_3 PF12776.7 CEP14234.1 - 0.013 16.4 1.4 6.1 7.9 0.9 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RGS_DHEX PF18148.1 CEP14234.1 - 0.032 14.4 1.3 0.12 12.5 1.3 2.0 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain GMC_oxred_C PF05199.13 CEP14234.1 - 0.15 12.6 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 GMC oxidoreductase DDE_3 PF13358.6 CEP14235.1 - 7.3e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 CEP14235.1 - 7.3e-07 28.8 0.0 2.6e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP14235.1 - 1.8e-05 24.7 0.8 5.2e-05 23.3 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CEP14235.1 - 0.00016 21.3 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CEP14235.1 - 0.0067 16.2 0.1 0.022 14.6 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain FeoC PF09012.10 CEP14235.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Tnp_ISL3 PF13542.6 CEP14235.1 - 0.017 14.5 0.0 0.064 12.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 CEP14235.1 - 0.022 15.4 1.0 0.11 13.1 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.6 CEP14235.1 - 0.035 14.1 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 CEP14235.1 - 0.086 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Yae1_N PF09811.9 CEP14237.1 - 3.8e-12 45.7 3.4 5.3e-12 45.2 3.4 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Strep_SA_rep PF06696.11 CEP14237.1 - 0.035 14.1 1.3 0.071 13.1 1.3 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Rap1_C PF11626.8 CEP14237.1 - 0.078 13.1 1.8 0.15 12.2 1.8 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LRR_8 PF13855.6 CEP14238.1 - 6.2e-27 93.1 18.3 6.8e-10 38.6 1.4 5.3 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEP14238.1 - 4.8e-22 77.7 27.0 8.9e-06 26.0 1.1 5.9 3 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP14238.1 - 0.00092 19.4 26.3 3.7 8.5 1.0 9.2 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 CEP14238.1 - 0.011 15.2 9.5 0.095 12.2 0.7 3.4 1 1 1 3 3 3 0 Leucine-rich repeat AA_permease_N PF08403.10 CEP14238.1 - 0.031 13.8 0.0 0.094 12.2 0.0 1.8 1 0 0 1 1 1 0 Amino acid permease N-terminal LRR_6 PF13516.6 CEP14238.1 - 0.96 9.7 30.8 0.63 10.3 0.1 7.3 8 0 0 8 8 8 0 Leucine Rich repeat Flavin_Reduct PF01613.18 CEP14239.1 - 2.1e-38 131.8 0.0 4.8e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 Flavin reductase like domain Arrestin_C PF02752.22 CEP14239.1 - 9.9e-11 42.2 0.8 1.2e-07 32.2 0.5 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP14239.1 - 4.3e-06 26.8 0.1 2.7e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Cyclin PF08613.11 CEP14240.1 - 5.2e-12 46.4 0.6 8.6e-12 45.7 0.6 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP14240.1 - 0.00038 20.2 0.5 0.00061 19.5 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LANC_like PF05147.13 CEP14240.1 - 0.026 13.1 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF3658 PF12395.8 CEP14240.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function TIG PF01833.24 CEP14241.1 - 2.2e-11 43.7 2.3 3.2e-10 40.0 0.1 3.1 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.30 CEP14241.1 - 2.8e-08 33.8 1.3 0.00017 21.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CEP14241.1 - 1.8e-06 28.4 0.7 4.2e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP14241.1 - 1.9e-05 25.1 0.7 4.1e-05 24.0 0.7 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP14241.1 - 0.00019 21.6 1.1 0.99 10.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEP14241.1 - 0.0046 17.2 0.6 0.1 13.0 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TIG_plexin PF17960.1 CEP14241.1 - 0.089 12.8 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 TIG domain SUIM_assoc PF16619.5 CEP14241.1 - 9.5 6.4 21.0 1.4 9.0 1.8 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Syja_N PF02383.18 CEP14242.1 - 8.3e-94 314.5 0.1 1.1e-93 314.0 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Fringe PF02434.16 CEP14242.1 - 0.067 12.6 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Fringe-like NAD_binding_10 PF13460.6 CEP14243.1 - 0.00052 20.0 0.2 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Glyco_transf_15 PF01793.16 CEP14243.1 - 0.11 11.8 2.6 0.08 12.2 0.9 1.6 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase RCC1 PF00415.18 CEP14245.1 - 3.7e-31 107.5 2.0 6.4e-08 33.1 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CEP14245.1 - 1.5e-17 63.8 2.0 3.3e-07 30.5 0.0 3.7 2 2 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 CEP14245.1 - 1.1e-14 54.6 0.8 1.1e-07 32.3 0.1 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP14245.1 - 2e-12 47.5 0.1 3.4e-11 43.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 CEP14245.1 - 9e-10 38.1 4.1 5.3e-08 32.5 0.1 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 CEP14245.1 - 4.8e-09 35.7 0.6 0.0078 16.6 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CEP14245.1 - 8.7e-09 35.4 0.1 0.0077 16.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CEP14245.1 - 2.6e-08 34.0 0.3 4.9e-06 26.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.25 CEP14246.1 - 1.8e-10 41.0 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP14246.1 - 9.5e-09 35.3 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP14246.1 - 8.1e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP14246.1 - 0.00023 21.1 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP14246.1 - 0.13 12.4 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Spt20 PF12090.8 CEP14248.1 - 0.13 11.9 5.0 1.2 8.7 0.5 2.0 2 0 0 2 2 2 0 Spt20 family Anti-TRAP PF15777.5 CEP14248.1 - 0.13 12.2 0.5 0.36 10.8 0.2 1.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SR-25 PF10500.9 CEP14248.1 - 1.9 8.0 16.3 1.5 8.3 5.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_1b PF00579.25 CEP14249.1 - 3.6e-71 239.9 0.0 4.9e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Exo_endo_phos PF03372.23 CEP14250.1 - 6.5e-08 32.4 0.2 1.1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ALAD PF00490.21 CEP14251.1 - 1.5e-126 421.9 0.0 1.8e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Phage_integrase PF00589.22 CEP14252.1 - 0.072 12.9 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 Phage integrase family Rox3 PF08633.10 CEP14252.1 - 0.098 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Rox3 mediator complex subunit Thiolase_N PF00108.23 CEP14254.1 - 1e-74 251.2 1.9 1.9e-74 250.3 1.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP14254.1 - 1.1e-45 154.2 0.0 2.2e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Guanylate_kin PF00625.21 CEP14255.1 - 4.7e-62 208.9 0.0 5.3e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CEP14255.1 - 4.6e-08 33.3 0.2 1.7e-06 28.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP14255.1 - 3.5e-06 27.3 0.0 1.2e-05 25.6 0.0 1.9 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 CEP14255.1 - 2.2e-05 25.0 0.0 5.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CEP14255.1 - 7e-05 22.9 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CEP14255.1 - 0.00011 22.8 0.0 0.00018 22.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CEP14255.1 - 0.00019 21.9 0.0 0.00038 20.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain ATPase_2 PF01637.18 CEP14255.1 - 0.0005 20.1 0.1 0.00061 19.8 0.1 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CEP14255.1 - 0.0017 18.8 0.1 0.034 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEP14255.1 - 0.0018 18.0 0.3 0.006 16.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP14255.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Thymidylate_kin PF02223.17 CEP14255.1 - 0.003 17.3 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.6 CEP14255.1 - 0.0036 17.3 0.0 0.0061 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CEP14255.1 - 0.0091 16.4 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 RNA helicase AAA_23 PF13476.6 CEP14255.1 - 0.011 16.3 2.7 0.011 16.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP14255.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 CEP14255.1 - 0.017 15.0 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 CEP14255.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 CEP14255.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CEP14255.1 - 0.026 14.1 0.2 0.077 12.6 0.0 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CEP14255.1 - 0.028 14.7 0.0 0.069 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CEP14255.1 - 0.03 14.1 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 CEP14255.1 - 0.032 14.5 0.2 0.29 11.4 0.0 2.1 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ADK PF00406.22 CEP14255.1 - 0.038 14.1 0.7 37 4.4 0.0 3.0 2 1 1 3 3 3 0 Adenylate kinase NB-ARC PF00931.22 CEP14255.1 - 0.04 13.1 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CEP14255.1 - 0.05 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CEP14255.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 CEP14255.1 - 0.075 12.9 0.0 0.59 10.0 0.0 2.3 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF5417 PF17438.2 CEP14255.1 - 0.095 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5417) AAA_7 PF12775.7 CEP14255.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CEP14255.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.12 CEP14255.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Adeno_IVa2 PF02456.15 CEP14255.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein CPT PF07931.12 CEP14255.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 CEP14255.1 - 0.18 11.0 0.0 0.61 9.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 CEP14256.1 - 5.6e-32 109.3 21.0 1.6e-06 28.7 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CEP14256.1 - 1.8e-12 46.7 5.6 0.008 14.9 0.1 5.5 3 1 2 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP14256.1 - 2.4e-09 37.0 0.0 8e-05 22.1 0.0 2.9 1 1 2 3 3 3 2 WD40-like domain F-box-like PF12937.7 CEP14256.1 - 1.7e-07 31.0 1.0 4.1e-07 29.8 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CEP14256.1 - 6.3e-07 29.3 0.2 1.6e-06 28.0 0.1 1.7 2 0 0 2 2 2 1 F-box ANAPC4_WD40 PF12894.7 CEP14256.1 - 7e-07 29.5 2.8 1 9.7 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CEP14256.1 - 1.5e-06 28.0 1.5 3.4e-06 26.8 1.5 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 CEP14256.1 - 0.00015 21.5 1.1 0.0098 15.5 0.3 2.3 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 CEP14256.1 - 0.21 12.1 0.5 30 5.3 0.3 3.6 1 1 2 3 3 3 0 PQQ-like domain Glyco_hydro_1 PF00232.18 CEP14257.1 - 0.091 11.2 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF3425 PF11905.8 CEP14258.1 - 1.2e-15 57.5 7.7 2.6e-15 56.5 0.6 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CEP14258.1 - 3.3e-08 33.5 5.0 7.4e-08 32.4 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEP14258.1 - 0.00041 20.4 4.7 0.0012 18.9 4.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF2205 PF10224.9 CEP14258.1 - 0.0016 18.4 2.0 0.0038 17.2 2.0 1.6 1 0 0 1 1 1 1 Short coiled-coil protein NRBF2 PF08961.10 CEP14258.1 - 0.0036 16.9 1.8 0.013 15.1 1.8 1.9 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator FCSD-flav_bind PF09242.11 CEP14258.1 - 0.12 12.8 2.1 3.4 8.1 0.0 3.0 3 0 0 3 3 3 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding DUF4635 PF15466.6 CEP14258.1 - 0.12 11.9 1.0 0.35 10.4 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) SHE3 PF17078.5 CEP14258.1 - 0.7 9.6 7.7 0.069 12.9 1.9 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 CEP14258.1 - 9.2 7.0 8.9 0.31 11.7 0.3 2.6 3 0 0 3 3 3 0 Initiation control protein YabA Glycos_transf_1 PF00534.20 CEP14259.1 - 1.5e-10 40.9 0.0 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CEP14259.1 - 6.2e-10 39.2 1.0 2.1e-09 37.4 0.5 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 CEP14259.1 - 3.4e-09 37.2 0.0 1.1e-08 35.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEP14259.1 - 7.5e-05 23.2 0.8 0.00015 22.3 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CEP14259.1 - 0.0014 18.6 0.4 0.0039 17.2 0.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Phage_integrase PF00589.22 CEP14262.1 - 2e-06 27.7 0.1 2.7e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family DDE_Tnp_4 PF13359.6 CEP14263.1 - 5e-20 71.8 0.0 1.4e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP14263.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_L14 PF00238.19 CEP14265.1 - 6.3e-47 158.7 1.2 7e-47 158.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DnaJ-X PF14308.6 CEP14266.1 - 1.3e-52 178.3 4.7 4.8e-52 176.5 0.3 2.4 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CEP14266.1 - 1.3e-23 82.9 1.7 3.1e-23 81.7 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3456 PF11938.8 CEP14266.1 - 0.1 13.1 3.2 0.78 10.2 0.1 2.8 3 0 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP zinc_ribbon_12 PF11331.8 CEP14266.1 - 0.13 12.1 0.5 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 Probable zinc-ribbon domain RRP7 PF12923.7 CEP14267.1 - 2.7e-34 117.8 16.6 2.7e-34 117.8 16.6 3.0 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 CEP14267.1 - 1.9e-15 57.1 1.0 4.7e-15 55.8 1.0 1.7 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CEP14267.1 - 0.023 14.5 0.0 0.62 9.9 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3338 PF11819.8 CEP14267.1 - 0.28 11.1 8.8 0.034 14.1 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) GOLD_2 PF13897.6 CEP14267.1 - 5.5 7.5 9.4 0.47 10.9 0.6 2.7 3 1 0 3 3 3 0 Golgi-dynamics membrane-trafficking Glyco_transf_24 PF18404.1 CEP14268.1 - 2.5e-147 489.4 7.6 5.2e-90 301.5 0.4 2.5 1 1 1 2 2 2 2 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CEP14268.1 - 1.5e-56 192.2 2.0 2.5e-55 188.2 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CEP14268.1 - 2.5e-39 134.3 0.1 1.5e-38 131.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CEP14268.1 - 2.5e-37 127.3 0.0 5.1e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 CEP14268.1 - 4e-34 118.4 2.2 1.6e-30 106.7 0.3 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CEP14268.1 - 2.6e-33 115.5 2.9 5.3e-33 114.5 2.9 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain MFS_1 PF07690.16 CEP14268.1 - 1.2e-12 47.5 35.3 1.3e-06 27.6 14.2 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_transf_8 PF01501.20 CEP14268.1 - 0.082 12.4 0.1 0.24 10.9 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 8 TraB PF01963.17 CEP14268.1 - 0.11 12.3 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 TraB family Forkhead PF00250.18 CEP14268.1 - 0.12 12.6 0.0 0.44 10.8 0.0 1.9 1 0 0 1 1 1 0 Forkhead domain F-box-like PF12937.7 CEP14269.1 - 6.6e-07 29.1 0.1 1.8e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP14269.1 - 0.012 15.5 2.8 0.016 15.1 0.3 2.4 2 0 0 2 2 2 0 F-box domain zf_C2H2_6 PF18450.1 CEP14269.1 - 2.7 7.8 5.6 59 3.5 0.2 3.5 2 1 1 3 3 3 0 Zinc Finger domain NAD_binding_10 PF13460.6 CEP14270.1 - 0.0033 17.3 0.0 0.0042 17.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Lipase_GDSL PF00657.22 CEP14271.1 - 3.2e-14 53.4 0.1 3.9e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP14271.1 - 3e-09 37.5 0.0 4.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PQ-loop PF04193.14 CEP14272.1 - 4.4e-29 100.0 7.1 8.2e-17 60.7 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 CEP14272.1 - 0.006 16.6 0.4 0.042 13.9 0.0 2.5 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Phosphonate-bd PF12974.7 CEP14272.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein RNase_T PF00929.24 CEP14273.1 - 2.3e-29 103.0 0.0 3.7e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease SAP PF02037.27 CEP14273.1 - 0.0022 17.7 0.5 0.0041 16.8 0.1 1.6 2 0 0 2 2 2 1 SAP domain DUF5051 PF16473.5 CEP14273.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like Imm44 PF15571.6 CEP14273.1 - 0.14 12.4 0.1 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 44 AA_permease_2 PF13520.6 CEP14274.1 - 1.1e-63 215.6 34.5 1.3e-63 215.3 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP14274.1 - 4.5e-33 114.6 33.5 6e-33 114.2 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease TraQ PF09679.10 CEP14274.1 - 6.7 6.7 6.3 3.6 7.6 0.0 3.3 4 0 0 4 4 4 0 Type-F conjugative transfer system pilin chaperone (TraQ) Ank_2 PF12796.7 CEP14275.1 - 4.4e-42 142.6 0.0 4.6e-14 52.8 0.0 3.7 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP14275.1 - 1.5e-20 71.1 0.6 0.0024 18.2 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CEP14275.1 - 3.8e-18 65.0 0.3 0.0004 20.7 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 CEP14275.1 - 2.6e-14 53.4 0.1 3e-06 27.7 0.0 4.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP14275.1 - 2.4e-13 50.0 0.4 0.003 17.8 0.1 4.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CorA PF01544.18 CEP14275.1 - 0.32 10.3 2.0 0.53 9.6 2.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SR-25 PF10500.9 CEP14275.1 - 4.7 6.7 19.6 1.8 8.1 1.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Prefoldin_2 PF01920.20 CEP14276.1 - 2.5e-19 69.2 2.4 3.1e-19 68.9 2.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4686 PF15742.5 CEP14276.1 - 0.088 11.9 5.3 0.86 8.7 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Seryl_tRNA_N PF02403.22 CEP14276.1 - 0.44 10.8 5.9 0.35 11.1 1.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-AN1 PF01428.16 CEP14277.1 - 8.5e-11 41.8 15.9 1.1e-10 41.5 5.5 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Caudo_TAP PF02413.17 CEP14277.1 - 0.019 15.1 1.5 0.028 14.6 1.5 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK zf-C2H2_4 PF13894.6 CEP14277.1 - 0.33 11.9 2.8 28 5.9 1.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger IBR PF01485.21 CEP14277.1 - 1.6 9.0 10.5 4.6 7.5 10.0 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Tim10_DDP PF02953.15 CEP14279.1 - 8.5e-25 86.2 2.7 2.1e-24 84.9 2.7 1.7 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HrpB2 PF09487.10 CEP14280.1 - 0.048 14.1 0.0 0.053 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) GTP_EFTU PF00009.27 CEP14281.1 - 1.2e-57 194.6 0.5 1.8e-57 194.1 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP14281.1 - 3.1e-30 104.7 1.4 3.6e-30 104.6 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CEP14281.1 - 3.1e-17 62.7 3.6 7.5e-17 61.5 3.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CEP14281.1 - 2.6e-05 24.3 0.1 4.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CEP14281.1 - 0.0021 17.7 0.6 0.0034 17.0 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CEP14281.1 - 0.0098 15.8 0.1 0.032 14.2 0.0 1.8 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CEP14281.1 - 0.017 14.9 0.2 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2917 PF11142.8 CEP14281.1 - 0.094 12.1 0.0 4.6 6.7 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2917) Alba PF01918.21 CEP14281.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Alba HEAT PF02985.22 CEP14282.1 - 1.7e-13 49.5 6.4 0.07 13.4 0.1 7.3 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 CEP14282.1 - 0.00042 20.6 4.9 0.22 11.9 0.0 5.4 5 2 0 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CEP14282.1 - 0.0082 16.2 1.5 0.6 10.1 0.0 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Stevor PF17410.2 CEP14282.1 - 0.042 13.4 0.6 0.093 12.3 0.6 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Adaptin_N PF01602.20 CEP14282.1 - 0.044 12.4 0.8 0.27 9.7 0.1 2.5 2 0 0 2 2 2 0 Adaptin N terminal region Mannosyl_trans3 PF11051.8 CEP14283.1 - 5.8e-46 157.1 3.7 1.2e-45 156.0 0.7 2.4 2 1 0 2 2 2 1 Mannosyltransferase putative EMC3_TMCO1 PF01956.16 CEP14283.1 - 0.83 9.4 3.7 0.19 11.5 0.3 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Glyco_transf_15 PF01793.16 CEP14284.1 - 3.4e-78 263.2 12.3 4.1e-78 262.9 12.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAGK PF15284.6 CEP14284.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Phage-encoded virulence factor EGF_3 PF12947.7 CEP14284.1 - 0.077 13.2 2.6 0.14 12.4 2.6 1.4 1 0 0 1 1 1 0 EGF domain Anti-TRAP PF15777.5 CEP14285.1 - 0.11 12.5 0.3 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein BLOC1_2 PF10046.9 CEP14287.1 - 0.00042 20.6 14.8 0.079 13.3 0.8 3.7 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 CEP14287.1 - 0.002 18.5 4.7 2.6 8.5 0.2 3.8 3 0 0 3 3 3 2 Lipoprotein leucine-zipper DUF4618 PF15397.6 CEP14287.1 - 0.0099 15.3 10.5 0.0099 15.3 10.5 2.6 1 1 2 3 3 3 2 Domain of unknown function (DUF4618) Syntaxin-6_N PF09177.11 CEP14287.1 - 0.084 13.4 14.3 0.96 10.0 4.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CEP14287.1 - 0.13 11.1 20.5 0.77 8.6 9.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 CEP14287.1 - 0.14 11.8 15.4 0.34 10.4 3.4 2.4 1 1 0 2 2 2 0 PspA/IM30 family Laminin_I PF06008.14 CEP14287.1 - 0.15 11.7 14.5 1.3 8.7 7.6 2.3 1 1 1 2 2 2 0 Laminin Domain I P4Ha_N PF08336.11 CEP14287.1 - 0.19 11.7 10.5 0.057 13.4 3.5 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UPF0242 PF06785.11 CEP14287.1 - 0.28 11.2 19.2 0.34 11.0 18.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2935 PF11155.8 CEP14287.1 - 0.34 11.3 3.5 1.2 9.5 3.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Cep57_MT_bd PF06657.13 CEP14287.1 - 0.34 11.4 10.6 0.75 10.3 0.2 3.5 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF745 PF05335.13 CEP14287.1 - 0.36 10.5 9.1 1.1 9.0 8.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Goodbye PF17109.5 CEP14287.1 - 0.57 10.7 4.8 0.25 11.8 1.6 2.1 2 1 1 3 3 2 0 fungal STAND N-terminal Goodbye domain DUF948 PF06103.11 CEP14287.1 - 0.64 10.3 10.9 0.4 11.0 1.5 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 CEP14287.1 - 1.3 9.1 10.4 8.4 6.6 0.6 3.1 1 1 1 2 2 2 0 TolA binding protein trimerisation Mod_r PF07200.13 CEP14287.1 - 1.5 8.9 15.7 1.7 8.7 5.8 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc29 PF17082.5 CEP14287.1 - 1.6 8.5 10.7 7.5 6.3 4.0 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 XkdW PF09636.10 CEP14287.1 - 2.1 8.5 6.0 0.48 10.5 0.9 2.6 3 0 0 3 3 3 0 XkdW protein PRKG1_interact PF15898.5 CEP14287.1 - 2.6 9.0 15.1 4.4 8.3 7.0 3.0 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain CSN5_C PF18323.1 CEP14287.1 - 2.7 9.0 9.9 93 4.0 9.9 2.4 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain YkyA PF10368.9 CEP14287.1 - 3 7.5 24.6 2.8 7.6 0.7 2.9 2 1 1 3 3 2 0 Putative cell-wall binding lipoprotein GrpE PF01025.19 CEP14287.1 - 3.4 7.3 15.8 0.86 9.3 2.4 2.9 1 1 1 2 2 2 0 GrpE FAM76 PF16046.5 CEP14287.1 - 4.4 6.6 15.5 17 4.7 14.5 2.0 1 1 1 2 2 2 0 FAM76 protein SlyX PF04102.12 CEP14287.1 - 4.7 7.9 16.2 1.6 9.4 2.9 3.8 2 1 1 3 3 3 0 SlyX YabA PF06156.13 CEP14287.1 - 4.8 7.9 16.2 0.9 10.2 2.0 3.6 2 1 2 4 4 3 0 Initiation control protein YabA DUF1192 PF06698.11 CEP14287.1 - 7.5 6.7 12.5 18 5.5 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) Ras PF00071.22 CEP14288.1 - 4.2e-43 146.7 0.6 3.3e-22 78.8 0.1 2.5 2 0 0 2 2 2 2 Ras family RhoGEF PF00621.20 CEP14288.1 - 7.1e-27 94.8 0.5 1.8e-26 93.5 0.5 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CEP14288.1 - 2.5e-23 82.7 1.8 2.5e-23 82.7 1.8 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Roc PF08477.13 CEP14288.1 - 2e-20 73.2 0.1 4.3e-19 68.9 0.1 2.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase CRAL_TRIO PF00650.20 CEP14288.1 - 1.3e-13 51.0 0.5 1.4e-12 47.6 0.1 2.9 2 1 0 2 2 2 1 CRAL/TRIO domain PB1 PF00564.24 CEP14288.1 - 3e-12 46.3 0.0 1.6e-11 44.0 0.0 2.3 1 0 0 1 1 1 1 PB1 domain Arf PF00025.21 CEP14288.1 - 0.00064 19.2 0.1 0.0072 15.8 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family CRAL_TRIO_N PF03765.15 CEP14288.1 - 0.0023 18.1 0.4 0.0081 16.3 0.4 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PH PF00169.29 CEP14288.1 - 0.0059 17.1 0.1 0.02 15.4 0.1 1.9 1 0 0 1 1 1 1 PH domain DUF1296 PF06972.11 CEP14288.1 - 0.071 13.3 1.1 0.75 10.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) PH_5 PF15405.6 CEP14288.1 - 0.69 10.0 2.7 1.3 9.2 0.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PLDc_2 PF13091.6 CEP14289.1 - 3.9e-14 52.7 0.0 4.9e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CEP14289.1 - 0.00072 19.6 2.2 0.2 11.9 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif OrfB_Zn_ribbon PF07282.11 CEP14290.1 - 0.013 15.4 0.0 0.12 12.3 0.0 2.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ADK PF00406.22 CEP14291.1 - 3.1e-47 160.5 0.0 4.8e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEP14291.1 - 3.6e-23 82.5 0.0 6.5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CEP14291.1 - 6.3e-13 48.5 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CEP14291.1 - 4.6e-08 33.7 0.0 9.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP14291.1 - 0.00043 20.4 0.0 0.0016 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CEP14291.1 - 0.032 14.5 0.0 0.087 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CEP14291.1 - 0.078 12.2 0.1 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 CEP14291.1 - 0.17 12.2 0.1 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 CEP14292.1 - 7.8e-26 90.0 1.0 1.4e-25 89.2 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 CEP14292.1 - 6.2e-12 45.7 21.5 2.1e-06 27.6 7.6 2.1 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Tmemb_9 PF05434.11 CEP14292.1 - 0.076 12.9 1.9 0.23 11.4 0.0 2.6 2 1 1 3 3 3 0 TMEM9 DUF3382 PF11862.8 CEP14292.1 - 0.91 9.8 8.7 0.12 12.7 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Phage_holin_3_6 PF07332.11 CEP14292.1 - 0.97 9.5 12.8 0.79 9.8 1.2 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2663 PF10864.8 CEP14292.1 - 3.1 8.2 10.6 0.79 10.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) GWT1 PF06423.12 CEP14292.1 - 6 7.0 10.6 10 6.2 0.3 2.7 2 1 1 3 3 3 0 GWT1 Peptidase_M18 PF02127.15 CEP14293.1 - 9.3e-170 565.1 0.1 1.1e-169 564.8 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CEP14293.1 - 1.5e-08 34.0 0.6 2e-06 27.0 0.2 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Aa_trans PF01490.18 CEP14294.1 - 2e-53 181.6 18.8 4e-32 111.4 10.8 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Med21 PF11221.8 CEP14294.1 - 5.3e-31 107.8 7.0 9.8e-31 106.9 7.0 1.4 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_permease PF03845.13 CEP14294.1 - 0.002 17.0 0.3 0.002 17.0 0.3 3.1 3 0 0 3 3 3 1 Spore germination protein Med9 PF07544.13 CEP14294.1 - 0.071 13.2 1.9 0.19 11.9 1.9 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ENT PF03735.14 CEP14294.1 - 0.085 12.9 0.3 0.25 11.4 0.3 1.8 1 0 0 1 1 1 0 ENT domain DUF727 PF05303.12 CEP14295.1 - 2.5e-11 43.6 0.1 5.1e-11 42.6 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF727) SUIM_assoc PF16619.5 CEP14295.1 - 0.046 13.8 7.9 0.092 12.8 7.9 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PP1_inhibitor PF05361.12 CEP14295.1 - 0.07 13.1 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor SKA1 PF07160.12 CEP14295.1 - 0.13 12.1 3.9 0.15 11.9 3.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ABC2_membrane PF01061.24 CEP14297.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Transposase_21 PF02992.14 CEP14301.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 DDE_3 PF13358.6 CEP14303.1 - 5e-11 42.6 0.0 1e-10 41.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP14303.1 - 2.1e-09 37.5 0.0 5.8e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 CEP14303.1 - 6.3e-05 22.9 0.3 0.00016 21.7 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CEP14303.1 - 0.055 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_40 PF14493.6 CEP14303.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Cu-oxidase_2 PF07731.14 CEP14304.1 - 1.1e-14 54.3 13.6 3.1e-11 43.2 5.3 3.7 2 2 1 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CEP14304.1 - 9.5e-07 28.8 5.6 3.4e-06 27.1 0.1 3.1 2 2 0 2 2 2 1 Multicopper oxidase MutS_V PF00488.21 CEP14305.1 - 5.4e-70 235.3 0.6 5.4e-70 235.3 0.6 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CEP14305.1 - 3.5e-39 135.0 2.1 6.9e-39 134.1 0.4 2.4 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 CEP14305.1 - 2.2e-28 98.7 0.0 4.4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CEP14305.1 - 8.3e-14 52.0 0.0 2.9e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CEP14305.1 - 2.2e-07 31.1 0.6 2.2e-07 31.1 0.6 2.5 2 0 0 2 2 2 1 MutS family domain IV CdvA PF18822.1 CEP14305.1 - 0.072 12.9 5.4 1 9.2 0.3 3.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain RRM_1 PF00076.22 CEP14306.1 - 4.3e-19 68.1 0.0 8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP14306.1 - 0.00019 21.5 0.0 0.00055 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CEP14306.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 CEP14307.1 - 1e-12 48.3 11.3 1.2e-06 28.9 1.5 3.0 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP14307.1 - 2.7e-11 43.9 5.4 2.3e-05 24.9 0.3 2.7 2 1 0 2 2 2 2 HMG-box domain Androgen_recep PF02166.16 CEP14308.1 - 0.11 11.3 13.6 0.13 11.1 13.6 1.4 1 0 0 1 1 1 0 Androgen receptor Ndc1_Nup PF09531.10 CEP14308.1 - 7.5 5.1 9.9 7.9 5.0 9.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UvrA_DNA-bind PF17755.1 CEP14309.1 - 0.05 14.0 0.1 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 UvrA DNA-binding domain ABC_membrane PF00664.23 CEP14310.1 - 3.2e-118 394.3 26.0 1.1e-61 208.9 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP14310.1 - 1.4e-67 226.4 6.7 5.1e-35 121.0 0.1 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CEP14310.1 - 4.2e-12 46.0 11.0 9.1e-06 25.3 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP14310.1 - 1.6e-08 34.9 2.4 0.0013 19.0 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP14310.1 - 3.7e-07 30.7 7.8 0.0044 17.4 0.2 3.6 2 2 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 CEP14310.1 - 6.1e-07 28.6 1.7 0.0067 15.3 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 CEP14310.1 - 3.1e-06 26.6 0.1 0.097 11.9 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 CEP14310.1 - 3.2e-06 27.0 1.4 0.047 13.4 0.3 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CEP14310.1 - 8.9e-06 25.4 2.4 0.026 14.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain G-alpha PF00503.20 CEP14310.1 - 2.4e-05 23.7 0.1 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 CEP14310.1 - 5e-05 23.3 0.1 0.42 10.5 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CEP14310.1 - 0.00014 22.4 4.6 1.7 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CEP14310.1 - 0.00015 22.2 5.4 0.48 10.8 1.5 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CEP14310.1 - 0.00055 19.9 0.0 0.076 12.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 CEP14310.1 - 0.0012 18.6 0.3 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CEP14310.1 - 0.0018 17.8 0.1 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CEP14310.1 - 0.0027 17.9 0.0 4.1 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CEP14310.1 - 0.0031 17.8 0.4 1.7 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CEP14310.1 - 0.0034 16.6 0.0 0.33 10.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 CEP14310.1 - 0.0046 16.7 3.6 0.17 11.5 0.3 3.4 3 1 0 3 3 2 1 AAA ATPase domain SbcCD_C PF13558.6 CEP14310.1 - 0.0064 16.7 4.7 3.9 7.8 0.6 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 CEP14310.1 - 0.0064 17.0 0.0 4.6 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CEP14310.1 - 0.0066 16.1 0.2 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 CEP14310.1 - 0.0068 16.8 0.2 4.8 7.6 0.0 3.6 4 0 0 4 4 3 0 RNA helicase PRK PF00485.18 CEP14310.1 - 0.012 15.4 0.1 4.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 CEP14310.1 - 0.018 15.1 0.5 8.8 6.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 CEP14310.1 - 0.021 14.6 5.3 3.8 7.2 0.1 4.5 3 2 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CEP14310.1 - 0.026 14.6 1.4 7.6 6.6 0.5 3.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 CEP14310.1 - 0.031 13.5 0.8 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 CEP14310.1 - 0.055 13.2 0.3 7.8 6.2 0.1 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3852 PF12963.7 CEP14310.1 - 0.072 13.4 1.2 0.17 12.2 0.2 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3852) Dala_Dala_lig_N PF01820.21 CEP14310.1 - 0.099 13.1 0.0 7.6 7.1 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus APS_kinase PF01583.20 CEP14310.1 - 0.1 12.5 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 CEP14310.1 - 0.15 11.5 0.0 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 CEP14310.1 - 0.2 11.7 8.7 0.27 11.3 0.0 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_19 PF13245.6 CEP14310.1 - 0.23 11.8 2.6 7.7 6.9 0.2 3.2 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 CEP14310.1 - 0.33 10.9 1.4 13 5.7 0.0 3.0 3 0 0 3 3 2 0 NACHT domain IstB_IS21 PF01695.17 CEP14310.1 - 2.8 7.6 5.8 29 4.3 0.0 4.3 5 0 0 5 5 4 0 IstB-like ATP binding protein Peroxidase_2 PF01328.17 CEP14311.1 - 3.4e-38 132.1 0.0 6e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 zf-C2H2_10 PF16588.5 CEP14312.1 - 0.014 15.1 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger MTHFR PF02219.17 CEP14313.1 - 1.6e-104 349.3 0.0 2.8e-104 348.5 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DnaJ PF00226.31 CEP14313.1 - 5.1e-20 71.4 0.0 1.2e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain HMG_box PF00505.19 CEP14314.1 - 4e-25 88.0 2.1 8.9e-25 86.9 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP14314.1 - 8.8e-17 61.5 3.2 2.5e-16 60.0 3.2 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CEP14314.1 - 0.003 17.5 1.2 0.003 17.5 1.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.12 CEP14314.1 - 0.0032 17.4 0.0 0.0095 15.9 0.0 1.7 2 0 0 2 2 2 1 CHDNT (NUC034) domain Fe_hyd_lg_C PF02906.14 CEP14314.1 - 0.072 12.8 1.7 0.092 12.4 1.7 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MEA1 PF06910.11 CEP14314.1 - 5.3 7.7 13.4 0.27 11.9 6.4 2.7 2 2 0 2 2 2 0 Male enhanced antigen 1 (MEA1) YABBY PF04690.13 CEP14314.1 - 9.4 6.8 6.7 34 5.0 6.8 2.1 1 1 0 1 1 1 0 YABBY protein HVSL PF09749.9 CEP14315.1 - 1.4e-38 132.7 5.7 1.2e-37 129.7 5.7 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein DUF3395 PF11875.8 CEP14316.1 - 3.8e-41 140.6 0.1 3.8e-41 140.6 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CEP14316.1 - 2.2e-17 62.9 3.2 3e-17 62.5 0.8 2.3 2 0 0 2 2 2 1 DnaJ domain KMP11 PF03037.16 CEP14316.1 - 9.3 7.1 9.3 0.9 10.4 0.6 2.7 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Chitin_synth_2 PF03142.15 CEP14317.1 - 2.1e-46 158.7 0.1 3.5e-46 157.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase SARAF PF06682.12 CEP14317.1 - 0.079 12.6 0.0 0.079 12.6 0.0 3.6 2 1 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis EptA_B_N PF08019.12 CEP14317.1 - 0.8 9.6 5.6 0.18 11.7 0.9 2.1 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB AA_permease_2 PF13520.6 CEP14317.1 - 9.5 4.9 11.0 1 8.1 1.3 2.4 3 0 0 3 3 3 0 Amino acid permease Chitin_synth_2 PF03142.15 CEP14318.1 - 8.4e-161 536.2 5.4 9.8e-161 535.9 5.4 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP14318.1 - 9.1e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP14318.1 - 4.2e-05 23.5 10.2 0.00016 21.7 9.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Dabb PF07876.12 CEP14319.1 - 4.9e-19 68.8 0.2 5.3e-19 68.6 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DAD PF02109.16 CEP14320.1 - 8.5e-30 103.3 0.2 1.7e-29 102.3 0.2 1.4 1 0 0 1 1 1 1 DAD family TFIIF_beta PF02270.15 CEP14320.1 - 3.4e-26 91.2 0.1 5.3e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CEP14320.1 - 7.8e-25 88.1 0.9 1.5e-23 83.9 0.5 2.8 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 CEP14320.1 - 0.012 16.5 0.1 0.028 15.2 0.1 1.8 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PLDc_3 PF13918.6 CEP14320.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 1 0 1 1 1 0 PLD-like domain NTNH_C PF08470.10 CEP14321.1 - 0.017 15.0 2.4 0.029 14.3 2.4 1.4 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal FAE1_CUT1_RppA PF08392.12 CEP14321.1 - 0.12 11.7 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Integrase_H2C2 PF17921.1 CEP14322.1 - 2e-11 43.8 1.6 3.6e-11 43.0 1.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP14322.1 - 7.2e-05 22.9 1.9 0.00015 21.9 1.9 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CEP14323.1 - 9e-09 35.1 0.8 1.6e-08 34.4 0.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP14323.1 - 0.0053 16.6 1.4 0.054 13.4 0.1 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain CRT10 PF08728.10 CEP14324.1 - 3.3e-09 35.5 7.8 2e-05 23.0 0.6 2.8 2 2 0 2 2 2 2 CRT10 ANAPC4_WD40 PF12894.7 CEP14324.1 - 2.4e-05 24.5 0.9 0.15 12.4 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP14324.1 - 5.2e-05 23.9 0.0 0.00051 20.8 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.8 CEP14324.1 - 0.015 14.0 0.0 0.031 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Peptidase_M18 PF02127.15 CEP14325.1 - 7.1e-172 572.0 0.0 9.9e-172 571.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) RFX_DNA_binding PF02257.15 CEP14325.1 - 5.6e-32 110.2 0.3 1.6e-31 108.7 0.3 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Peptidase_M42 PF05343.14 CEP14325.1 - 2.3e-05 23.6 0.1 0.00016 20.8 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Pox_D5 PF03288.16 CEP14325.1 - 3.1e-05 24.4 1.2 0.00014 22.3 0.0 2.6 3 0 0 3 3 3 1 Poxvirus D5 protein-like Tli4_C PF18426.1 CEP14326.1 - 0.18 12.1 0.0 1.6 9.0 0.0 2.0 1 1 1 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain EMP70 PF02990.16 CEP14327.1 - 1.6e-201 670.5 5.2 2e-201 670.2 5.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MGC-24 PF05283.11 CEP14328.1 - 0.094 13.2 0.9 0.16 12.4 0.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TCTP PF00838.17 CEP14329.1 - 1.7e-63 213.9 2.5 1.9e-63 213.8 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Histone_HNS PF00816.21 CEP14329.1 - 0.018 15.9 0.0 0.028 15.2 0.0 1.3 1 0 0 1 1 1 0 H-NS histone family FAM86 PF14904.6 CEP14329.1 - 0.044 13.9 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function DUF5402 PF17393.2 CEP14329.1 - 0.054 13.4 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5402) Sec63 PF02889.16 CEP14331.1 - 3.5e-146 485.1 0.1 4.6e-80 268.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CEP14331.1 - 7.8e-54 182.1 0.5 8.7e-27 94.0 0.5 4.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CEP14331.1 - 6.2e-26 91.4 0.0 1.2e-12 48.2 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP14331.1 - 1e-17 64.5 0.0 1.2e-07 32.1 0.0 3.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CEP14331.1 - 1.5e-06 28.5 0.1 0.24 11.7 0.3 3.9 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEP14331.1 - 2.5e-06 27.3 0.6 0.029 14.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CEP14331.1 - 7.7e-06 26.4 0.8 0.054 13.9 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 CEP14331.1 - 2.6e-05 24.4 1.3 0.00019 21.6 0.7 2.6 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_19 PF13245.6 CEP14331.1 - 0.00057 20.2 1.2 0.12 12.7 0.3 3.3 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CEP14331.1 - 0.03 14.1 0.2 7.2 6.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 CEP14331.1 - 0.044 13.4 0.0 2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CEP14331.1 - 0.058 12.8 0.0 3.9 6.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 CEP14331.1 - 0.16 12.5 6.6 15 6.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 CEP14331.1 - 0.92 9.2 5.4 33 4.2 0.0 4.2 3 1 1 4 4 4 0 AAA domain Gp_dh_C PF02800.20 CEP14332.1 - 5.1e-71 237.4 0.0 7.1e-71 236.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEP14332.1 - 6.1e-40 135.6 0.1 1.5e-39 134.4 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Arf PF00025.21 CEP14333.1 - 2.6e-45 154.0 0.0 3.3e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CEP14333.1 - 1e-12 48.0 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP14333.1 - 3.7e-12 46.5 0.0 7.8e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEP14333.1 - 1.5e-10 40.8 0.1 3e-07 29.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEP14333.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEP14333.1 - 2.6e-09 36.8 0.0 3.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEP14333.1 - 1.1e-08 34.8 0.1 7.4e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP14333.1 - 2.1e-08 34.3 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CEP14333.1 - 0.006 17.1 0.1 0.008 16.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CEP14333.1 - 0.019 14.5 0.1 0.059 12.9 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 CEP14333.1 - 0.02 15.2 0.0 0.066 13.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 CEP14333.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2672 PF10878.8 CEP14333.1 - 0.085 12.8 0.9 16 5.5 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) PduV-EutP PF10662.9 CEP14333.1 - 0.11 12.2 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CEP14333.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CEP14333.1 - 0.18 11.5 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Phage_integrase PF00589.22 CEP14335.1 - 0.0017 18.2 0.0 0.0052 16.6 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 CEP14335.1 - 0.013 15.8 0.4 0.037 14.3 0.4 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF4837 PF16125.5 CEP14335.1 - 0.041 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) Phage_int_SAM_4 PF13495.6 CEP14335.1 - 0.06 13.8 0.3 0.14 12.6 0.3 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain MFS_1 PF07690.16 CEP14337.1 - 1.6e-48 165.5 46.1 1.9e-48 165.2 43.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP14337.1 - 1.3e-16 60.6 4.7 1.3e-16 60.6 4.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CEP14337.1 - 4.2e-09 35.4 11.2 4.2e-09 35.4 11.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2157 PF09925.9 CEP14337.1 - 0.12 12.2 8.8 0.11 12.2 1.4 3.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) HECT PF00632.25 CEP14339.1 - 1.2e-67 228.6 0.0 2.4e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C58 PF03543.14 CEP14339.1 - 0.14 11.8 0.2 0.37 10.5 0.2 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen LZ3wCH PF18517.1 CEP14339.1 - 0.28 11.3 1.9 1.1 9.4 0.1 2.7 2 0 0 2 2 2 0 Leucine zipper with capping helix domain zf-3CxxC_2 PF17180.4 CEP14340.1 - 3.7e-11 43.6 10.1 3.7e-11 43.6 10.1 2.2 2 0 0 2 2 2 1 Zinc-binding domain zf-3CxxC PF13695.6 CEP14340.1 - 2 8.9 18.6 15 6.1 13.3 3.4 2 1 0 2 2 2 0 Zinc-binding domain HypA PF01155.19 CEP14340.1 - 2.4 8.2 6.1 7.1 6.7 6.1 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fer4_10 PF13237.6 CEP14340.1 - 5.2 7.3 9.4 4.2 7.6 4.6 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L5e PF17144.4 CEP14341.1 - 1.4e-83 278.8 0.1 2.8e-83 277.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CEP14341.1 - 2.8e-28 98.7 2.8 2.8e-28 98.7 2.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAP1_N PF04849.13 CEP14342.1 - 0.0013 18.0 0.1 0.0013 18.0 0.1 2.5 2 1 0 2 2 2 1 HAP1 N-terminal conserved region Amidinotransf PF02274.17 CEP14342.1 - 0.021 13.9 0.2 0.021 13.9 0.2 1.9 2 0 0 2 2 2 0 Amidinotransferase LRR19-TM PF15176.6 CEP14342.1 - 0.1 12.6 1.4 0.29 11.1 0.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain YjfB_motility PF14070.6 CEP14342.1 - 0.41 10.8 2.5 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Putative motility protein HMMR_N PF15905.5 CEP14342.1 - 1 8.8 24.7 5.2 6.5 24.7 2.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 CEP14342.1 - 1.6 9.3 10.6 9.3 6.8 0.4 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 CEP14342.1 - 2.1 7.6 28.8 0.58 9.5 6.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 CEP14342.1 - 8.6 6.7 14.9 6 7.2 1.5 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) PRORP PF16953.5 CEP14343.1 - 0.019 14.5 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein-only RNase P zf-RVT PF13966.6 CEP14344.1 - 0.029 15.1 0.1 0.042 14.6 0.1 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 CEP14346.1 - 0.00033 20.6 9.9 0.064 13.4 1.7 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP14346.1 - 0.00087 19.0 12.1 0.0013 18.4 3.3 2.3 2 0 0 2 2 2 2 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CEP14346.1 - 0.002 17.8 7.5 0.31 10.8 2.0 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CHC2 PF01807.20 CEP14346.1 - 0.064 13.1 0.5 0.2 11.5 0.8 1.7 2 0 0 2 2 2 0 CHC2 zinc finger zf-nanos PF05741.13 CEP14346.1 - 0.26 11.6 7.4 1.3 9.3 7.4 2.0 1 1 0 1 1 1 0 Nanos RNA binding domain RVT_1 PF00078.27 CEP14347.1 - 3.3e-21 75.8 0.0 8e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRIF-NTD PF17798.1 CEP14347.1 - 0.14 12.2 0.0 3.4 7.7 0.0 2.7 3 0 0 3 3 3 0 TRIF N-terminal domain zinc_ribbon_9 PF14369.6 CEP14348.1 - 2.1e-08 34.3 6.9 0.096 13.0 0.2 4.4 4 0 0 4 4 4 2 zinc-ribbon zf-RING_7 PF02591.15 CEP14348.1 - 3.6e-05 23.9 9.3 0.3 11.3 0.4 4.5 4 0 0 4 4 4 2 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 CEP14348.1 - 0.00052 20.1 7.6 0.94 9.7 0.3 3.7 4 0 0 4 4 4 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CEP14348.1 - 0.0013 18.6 17.6 0.33 11.0 0.8 3.7 4 0 0 4 4 4 3 Transposase zinc-ribbon domain UPF0547 PF10571.9 CEP14348.1 - 0.0016 18.5 9.7 1.7 8.8 0.4 3.6 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 CEP14348.1 - 0.0044 16.4 14.9 0.38 10.2 0.7 3.8 4 0 0 4 4 4 2 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.19 CEP14348.1 - 0.0074 16.6 9.2 0.0074 16.6 9.2 2.7 1 1 0 2 2 2 1 DnaJ central domain zinc_ribbon_10 PF10058.9 CEP14348.1 - 0.0087 15.8 2.5 5.9 6.7 0.2 3.4 3 0 0 3 3 3 1 Predicted integral membrane zinc-ribbon metal-binding protein Lar_restr_allev PF14354.6 CEP14348.1 - 0.011 16.1 13.8 2 8.9 0.1 3.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_1 PF14446.6 CEP14348.1 - 0.024 14.6 19.0 0.35 10.8 2.3 3.7 1 1 2 3 3 3 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.12 CEP14348.1 - 0.024 14.6 7.4 2.1 8.4 0.2 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-LITAF-like PF10601.9 CEP14348.1 - 0.034 14.4 7.6 1.3 9.3 0.2 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.6 CEP14348.1 - 0.081 12.7 13.6 2.9 7.7 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DUF1356 PF07092.12 CEP14348.1 - 0.22 10.7 3.9 4 6.6 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Cys_rich_KTR PF14205.6 CEP14348.1 - 0.23 11.3 2.6 49 3.8 0.0 3.4 3 0 0 3 3 3 0 Cysteine-rich KTR zf-Di19 PF05605.12 CEP14348.1 - 0.3 11.4 10.3 6.7 7.1 0.2 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-FPG_IleRS PF06827.14 CEP14348.1 - 0.31 11.0 6.8 5.5 6.9 0.1 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS HypA PF01155.19 CEP14348.1 - 0.31 11.1 5.7 5.3 7.1 1.4 2.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 CEP14348.1 - 0.65 9.7 5.9 26 4.6 0.1 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Cys_rich_CPXG PF14255.6 CEP14348.1 - 0.76 9.7 10.6 17 5.4 0.4 3.8 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-C2H2_4 PF13894.6 CEP14348.1 - 1.1 10.3 6.3 1.1e+02 4.0 0.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger FYDLN_acid PF09538.10 CEP14348.1 - 1.4 9.6 3.8 3.7 8.3 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-TFIIB PF13453.6 CEP14348.1 - 2.2 7.7 9.0 8 5.9 0.2 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-C4_Topoisom PF01396.19 CEP14348.1 - 2.3 8.1 13.5 6.3 6.7 0.1 4.1 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CEP14348.1 - 3.3 7.9 30.0 1.9 8.7 1.9 4.8 5 0 0 5 5 4 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 CEP14348.1 - 3.3 8.1 16.5 6.1 7.2 0.2 3.6 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase zinc-ribbons_6 PF07191.12 CEP14348.1 - 4.6 7.3 9.2 33 4.6 3.3 3.1 2 1 1 3 3 3 0 zinc-ribbons DUF1272 PF06906.11 CEP14348.1 - 4.9 7.3 9.6 7.7 6.7 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf_Rg PF17915.1 CEP14348.1 - 6.6 6.2 7.3 11 5.6 0.2 3.0 3 0 0 3 3 3 0 Reverse gyrase zinc finger DUF1610 PF07754.11 CEP14348.1 - 9.5 6.3 14.0 4.1 7.5 0.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) DDE_3 PF13358.6 CEP14349.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP14349.1 - 0.027 15.1 0.0 0.052 14.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Hamartin PF04388.12 CEP14350.1 - 4.6e-12 45.5 33.4 1.6e-10 40.4 33.4 3.1 1 1 0 1 1 1 1 Hamartin protein DHR10 PF18595.1 CEP14350.1 - 0.0022 18.0 10.9 0.0022 18.0 10.9 4.5 2 1 3 5 5 5 1 Designed helical repeat protein 10 domain Roughex PF06020.11 CEP14350.1 - 0.028 13.5 4.3 0.054 12.6 4.3 1.4 1 0 0 1 1 1 0 Drosophila roughex protein V-SNARE_C PF12352.8 CEP14350.1 - 0.055 13.8 3.1 0.059 13.7 0.3 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Nucleoporin_FG2 PF15967.5 CEP14350.1 - 0.092 11.3 2.9 0.15 10.6 2.9 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region BLOC1_2 PF10046.9 CEP14350.1 - 3.9 7.8 25.2 0.045 14.0 2.0 4.7 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DDE_3 PF13358.6 CEP14351.1 - 3.1e-11 43.2 0.0 1.2e-05 25.1 0.0 3.2 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_28 PF13518.6 CEP14351.1 - 0.00027 21.0 0.7 0.001 19.1 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP14351.1 - 0.0016 18.5 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix PI3_PI4_kinase PF00454.27 CEP14351.1 - 0.055 13.3 0.1 0.076 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase HTH_32 PF13565.6 CEP14351.1 - 0.11 13.1 0.0 0.29 11.8 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.6 CEP14352.1 - 1.2e-22 80.2 0.0 2.3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.16 CEP14352.1 - 1.5e-05 24.6 0.0 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP14352.1 - 0.00013 22.0 1.1 0.00035 20.6 1.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 CEP14352.1 - 0.0014 18.2 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 CEP14352.1 - 0.0031 17.3 0.3 0.0089 15.8 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 CEP14352.1 - 0.021 14.3 0.7 0.096 12.2 0.3 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_3 PF01381.22 CEP14352.1 - 0.023 14.7 0.1 0.064 13.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_32 PF13565.6 CEP14352.1 - 0.036 14.7 4.1 0.064 13.9 0.0 3.1 3 1 1 4 4 4 0 Homeodomain-like domain HTH_29 PF13551.6 CEP14352.1 - 0.038 14.0 0.1 0.084 12.9 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix FeoC PF09012.10 CEP14352.1 - 0.048 13.7 0.3 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_37 PF13744.6 CEP14352.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2_jaz PF12171.8 CEP14353.1 - 0.0072 16.6 0.6 0.022 15.0 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding amfpi-1 PF12190.8 CEP14353.1 - 0.041 14.5 0.6 6.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Fungal protease inhibitor zf-met PF12874.7 CEP14353.1 - 0.05 14.0 0.1 0.23 11.9 0.1 2.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP14353.1 - 0.079 13.8 3.6 0.17 12.8 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP14353.1 - 0.082 13.4 3.1 0.94 10.1 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type PIF1 PF05970.14 CEP14354.1 - 9.9e-33 113.8 0.1 1.7e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP14354.1 - 7.3e-14 51.9 0.0 2.8e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP14354.1 - 7.7e-09 36.0 0.0 2.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP14354.1 - 6.3e-05 23.3 0.0 0.00038 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEP14354.1 - 0.0044 17.4 0.0 0.048 14.0 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 CEP14354.1 - 0.0062 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CEP14354.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family TniB PF05621.11 CEP14354.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF87 PF01935.17 CEP14354.1 - 0.064 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain Sigma54_activat PF00158.26 CEP14354.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CEP14354.1 - 0.091 12.7 0.1 0.82 9.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 CEP14354.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 CEP14354.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 CEP14354.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 CEP14354.1 - 0.16 12.4 0.1 0.59 10.6 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fanconi_A_N PF15865.5 CEP14355.1 - 0.00011 21.8 2.3 0.00029 20.3 0.1 2.2 2 0 0 2 2 2 1 Fanconi anaemia group A protein N terminus RhoGAP PF00620.27 CEP14356.1 - 1.9e-14 53.8 0.7 1.9e-14 53.8 0.7 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 CEP14356.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CSF-1 PF05337.11 CEP14356.1 - 0.094 12.8 1.5 2.2 8.4 0.0 3.2 3 0 0 3 3 3 0 Macrophage colony stimulating factor-1 (CSF-1) Stathmin PF00836.19 CEP14356.1 - 0.54 10.2 4.5 0.44 10.5 0.2 2.6 3 0 0 3 3 3 0 Stathmin family Rotamase PF00639.21 CEP14357.1 - 1.5e-24 86.8 0.0 1.9e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CEP14357.1 - 6.9e-20 71.7 0.0 8.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CEP14357.1 - 4.7e-08 33.0 3.1 4.7e-08 33.0 3.1 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 CEP14357.1 - 0.00048 21.0 0.0 0.00064 20.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain BK_channel_a PF03493.18 CEP14358.1 - 4.4e-25 87.7 0.0 4e-24 84.7 0.0 2.7 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CEP14358.1 - 5.7e-14 51.8 1.8 5.7e-14 51.8 1.8 2.1 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 CEP14358.1 - 0.00021 21.6 0.0 0.53 10.6 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.31 CEP14358.1 - 0.022 14.0 14.8 0.054 12.7 14.8 1.6 1 1 0 1 1 1 0 Ion transport protein DDE_3 PF13358.6 CEP14359.1 - 2.1e-11 43.7 0.0 2.4e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40 PF00400.32 CEP14360.1 - 3.7e-14 52.9 10.3 0.00028 21.6 1.2 6.5 5 1 0 5 5 5 3 WD domain, G-beta repeat Prot_ATP_ID_OB PF16450.5 CEP14360.1 - 0.13 12.2 0.0 0.43 10.6 0.0 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Ge1_WD40 PF16529.5 CEP14360.1 - 0.13 11.2 0.0 9.2 5.1 0.0 3.2 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 CEP14361.1 - 0.00028 20.7 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CEP14361.1 - 0.0078 16.6 11.6 0.76 10.3 0.2 5.4 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 CEP14361.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain DDE_3 PF13358.6 CEP14362.1 - 2.8e-27 95.3 0.0 5.2e-19 68.4 0.0 2.8 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_29 PF13551.6 CEP14362.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 CEP14362.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 CEP14362.1 - 0.0026 17.5 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP14362.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CEP14362.1 - 0.016 15.3 0.2 0.08 13.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 CEP14362.1 - 0.071 13.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP14362.1 - 0.1 12.9 0.3 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Transposase AAA_14 PF13173.6 CEP14362.1 - 0.14 12.2 0.1 0.69 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain TauD PF02668.16 CEP14363.1 - 9.8e-59 199.3 1.5 1.4e-58 198.8 1.5 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LRR_4 PF12799.7 CEP14364.1 - 0.034 14.6 2.9 25 5.5 0.2 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) CotH PF08757.11 CEP14365.1 - 1.3e-39 136.6 1.7 1.7e-39 136.2 1.7 1.1 1 0 0 1 1 1 1 CotH kinase protein DUF4420 PF14390.6 CEP14365.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) DUF5305 PF17231.2 CEP14366.1 - 0.011 15.2 0.5 0.027 13.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 CEP14366.1 - 0.021 14.6 1.2 0.029 14.1 1.2 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 CEP14366.1 - 0.071 14.0 2.3 0.13 13.1 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 7TM_GPCR_Srv PF10323.9 CEP14366.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Insulin_TMD PF17870.1 CEP14366.1 - 0.1 12.7 0.3 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CD34_antigen PF06365.12 CEP14366.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.4 2 1 2 4 4 4 0 CD34/Podocalyxin family ECSCR PF15820.5 CEP14366.1 - 0.16 11.8 0.2 0.16 11.8 0.2 3.7 3 1 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator PsbJ PF01788.17 CEP14366.1 - 2.5 8.0 6.4 4.5 7.2 6.4 1.3 1 0 0 1 1 1 0 PsbJ Peptidase_C12 PF01088.21 CEP14367.1 - 6.7e-60 202.4 0.1 1.3e-59 201.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UBX PF00789.20 CEP14367.1 - 2.8e-07 30.6 0.0 9.9e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 UBX domain CCDC50_N PF15295.6 CEP14367.1 - 0.0077 16.4 0.7 0.029 14.5 0.5 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 50 N-terminus DUF3759 PF12585.8 CEP14368.1 - 4e-37 126.1 7.0 4.5e-37 126.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3419 PF11899.8 CEP14368.1 - 0.018 14.2 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DUF5075 PF16825.5 CEP14368.1 - 0.05 13.3 2.4 3.2 7.4 0.4 2.1 2 0 0 2 2 2 0 IGP family C-type lectin domain Peptidase_M24 PF00557.24 CEP14369.1 - 6.6e-51 173.0 0.0 8.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 SRA1 PF07304.11 CEP14369.1 - 0.00035 20.4 0.0 0.00085 19.1 0.0 1.6 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 CEP14369.1 - 0.029 14.4 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain DUF1363 PF07101.11 CEP14370.1 - 0.0024 18.2 0.4 0.014 15.7 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1363) Helitron_like_N PF14214.6 CEP14371.1 - 4.5e-32 111.8 0.1 4e-23 82.6 0.0 2.5 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus DUF3323 PF11796.8 CEP14374.1 - 0.14 12.0 0.4 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUSP PF06337.12 CEP14375.1 - 2.3e-10 40.9 0.6 5.7e-10 39.7 0.0 1.9 3 0 0 3 3 3 1 DUSP domain zf-UBP PF02148.19 CEP14375.1 - 6.6e-07 29.6 5.3 1.4e-06 28.5 4.5 1.9 1 1 1 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein F-box PF00646.33 CEP14375.1 - 0.0036 17.1 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP14375.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Maf1 PF09174.10 CEP14376.1 - 1.1e-25 90.8 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator zf-C2H2 PF00096.26 CEP14377.1 - 1.4e-09 37.9 6.9 1.2e-05 25.5 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP14377.1 - 2.3e-07 30.9 1.4 2.3e-07 30.9 1.4 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP14377.1 - 0.0016 19.1 6.4 0.31 12.0 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP14377.1 - 0.0042 17.0 0.1 0.0042 17.0 0.1 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP14377.1 - 0.39 11.1 9.5 0.068 13.5 1.4 3.2 2 2 2 4 4 4 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP14377.1 - 2.1 9.0 9.7 0.73 10.5 1.1 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain Presenilin PF01080.17 CEP14377.1 - 5 5.8 6.0 6 5.5 6.0 1.1 1 0 0 1 1 1 0 Presenilin TIM PF00121.18 CEP14379.1 - 1.6e-91 306.1 0.0 1.8e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PilM PF07419.12 CEP14379.1 - 0.011 15.8 0.0 2 8.6 0.0 2.4 2 1 0 2 2 2 0 PilM Thioredoxin_7 PF13899.6 CEP14380.1 - 5.5e-19 68.1 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 CEP14380.1 - 1.4e-11 44.4 0.0 3.7e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CEP14380.1 - 3.8e-09 36.2 0.5 9.7e-09 34.9 0.5 1.8 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.6 CEP14380.1 - 0.00014 22.3 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain UIM PF02809.20 CEP14380.1 - 0.029 14.3 1.7 0.035 14.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1642 PF07852.11 CEP14381.1 - 0.031 14.9 0.4 0.054 14.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) HATPase_c_5 PF14501.6 CEP14381.1 - 0.094 12.6 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 GHKL domain RVT_1 PF00078.27 CEP14385.1 - 5.4e-15 55.5 0.7 9.8e-15 54.7 0.7 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxysterol_BP PF01237.18 CEP14386.1 - 5.1e-65 219.7 11.5 8.3e-60 202.6 0.1 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Hexokinase_2 PF03727.16 CEP14387.1 - 8e-77 257.9 0.0 1.4e-76 257.1 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP14387.1 - 1.2e-53 182.0 0.0 1.7e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1160 PF06648.11 CEP14387.1 - 0.039 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Vps5 PF09325.10 CEP14388.1 - 1.4e-11 44.4 12.3 1.4e-11 44.4 12.3 2.5 2 1 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CEP14388.1 - 1.4e-09 38.0 0.2 1.4e-09 38.0 0.2 2.4 2 1 0 2 2 2 1 PX domain FAM92 PF06730.11 CEP14388.1 - 0.0019 17.6 2.8 0.0047 16.4 2.8 1.6 1 0 0 1 1 1 1 FAM92 protein DUF1993 PF09351.10 CEP14388.1 - 0.031 14.4 0.4 0.075 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) T2SSM PF04612.12 CEP14388.1 - 5.2 7.1 6.3 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M RabGAP-TBC PF00566.18 CEP14389.1 - 6.2e-44 150.2 4.0 1.9e-43 148.6 4.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain IATP PF04568.12 CEP14389.1 - 3.1 8.3 7.8 8.7 6.8 7.8 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Chitin_synth_2 PF03142.15 CEP14390.1 - 3.5e-233 775.0 3.4 5e-233 774.5 3.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP14390.1 - 2.6e-109 366.4 8.1 5.1e-107 358.8 8.1 3.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 CEP14390.1 - 2.6e-16 59.2 0.2 1.1e-15 57.3 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 CEP14390.1 - 2.5e-13 50.4 4.6 2.5e-13 50.4 4.6 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP14390.1 - 3.1e-13 50.2 0.4 2e-12 47.5 0.1 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 CEP14390.1 - 1.5e-11 44.2 0.5 6.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 CEP14390.1 - 0.0042 16.9 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP14390.1 - 0.012 15.1 0.1 0.096 12.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF389 PF04087.14 CEP14390.1 - 0.02 14.9 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF389) CTU2 PF10288.9 CEP14391.1 - 9.1e-20 71.0 0.4 9.1e-20 71.0 0.4 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 CEP14391.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 PP-loop family DUF2515 PF10720.9 CEP14391.1 - 0.078 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) SLAC1 PF03595.17 CEP14393.1 - 3.7e-51 174.3 25.0 4.2e-51 174.1 25.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ras PF00071.22 CEP14394.1 - 1.7e-46 157.8 0.6 2.2e-46 157.4 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP14394.1 - 5.9e-21 74.9 0.1 1e-20 74.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP14394.1 - 1e-08 34.8 0.2 1.3e-08 34.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP14394.1 - 0.0028 17.2 0.1 0.0043 16.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_15 PF00723.21 CEP14395.1 - 5.5e-65 219.9 0.1 7.3e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RNase_T PF00929.24 CEP14396.1 - 3.6e-14 53.6 0.0 7.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CEP14396.1 - 0.0032 17.2 0.0 0.033 13.9 0.0 2.5 1 1 1 2 2 2 1 3'-5' exonuclease ING PF12998.7 CEP14397.1 - 1.6e-18 67.2 7.9 2.3e-18 66.6 7.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEP14397.1 - 3.7e-06 26.7 8.3 6.9e-06 25.9 8.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEP14397.1 - 0.0056 16.9 0.8 0.016 15.5 0.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain HEPN-like_int PF18867.1 CEP14397.1 - 0.014 15.3 0.2 0.021 14.7 0.2 1.3 1 0 0 1 1 1 0 HEPN-like integron domain PHD_2 PF13831.6 CEP14397.1 - 0.021 14.4 2.1 0.039 13.5 2.1 1.5 1 0 0 1 1 1 0 PHD-finger MPS2 PF17060.5 CEP14397.1 - 0.027 13.7 1.3 0.034 13.4 1.3 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 STELLO PF03385.17 CEP14397.1 - 0.085 11.7 2.1 0.076 11.8 0.8 1.5 2 0 0 2 2 2 0 STELLO glycosyltransferases RAG2_PHD PF13341.6 CEP14397.1 - 0.089 12.9 1.0 0.18 11.8 1.0 1.5 1 0 0 1 1 1 0 RAG2 PHD domain Fas_alpha_ACP PF18325.1 CEP14397.1 - 0.11 12.9 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain RE_BstXI PF09552.10 CEP14397.1 - 0.11 11.6 0.4 0.16 11.1 0.4 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease FapA PF03961.13 CEP14397.1 - 0.28 9.8 2.0 0.38 9.3 2.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 CEP14397.1 - 0.29 11.3 6.0 0.56 10.4 6.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Amidase PF01425.21 CEP14398.1 - 3.2e-88 296.7 0.0 5.2e-88 296.0 0.0 1.3 1 1 0 1 1 1 1 Amidase Thioredoxin PF00085.20 CEP14400.1 - 1.1e-27 96.0 0.1 1.4e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CEP14400.1 - 4.2e-05 24.0 0.1 0.0014 19.1 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP14400.1 - 9.8e-05 22.6 0.0 0.00059 20.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEP14400.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEP14400.1 - 0.00022 21.3 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CEP14400.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 CEP14400.1 - 0.0005 20.0 0.0 0.00068 19.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CEP14400.1 - 0.0056 16.1 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 CEP14400.1 - 0.028 14.8 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Phosducin PF02114.16 CEP14400.1 - 0.053 12.5 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin Nic96 PF04097.14 CEP14401.1 - 6.8e-107 358.4 12.8 1.1e-106 357.7 12.8 1.3 1 0 0 1 1 1 1 Nup93/Nic96 Kelch_4 PF13418.6 CEP14402.1 - 1.8e-21 75.9 16.2 3.1e-05 23.9 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP14402.1 - 5.1e-16 58.3 6.1 0.0013 18.7 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CEP14402.1 - 1.8e-13 50.2 12.8 0.18 12.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEP14402.1 - 9.5e-12 44.9 25.4 4.6e-05 23.6 0.3 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP14402.1 - 1.9e-07 30.6 13.4 2.4e-05 23.8 0.1 5.3 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 CEP14402.1 - 3.3e-07 30.0 5.6 6.8 6.8 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Vps55 PF04133.14 CEP14403.1 - 0.051 13.5 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 55 MULE PF10551.9 CEP14403.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 2 0 0 2 2 2 0 MULE transposase domain PUF PF00806.19 CEP14404.1 - 3.6e-66 215.3 19.4 1.7e-08 33.7 0.0 9.1 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Paramyxo_ncap PF00973.19 CEP14404.1 - 4.1 6.2 7.5 6.6 5.5 7.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CUE PF02845.16 CEP14405.1 - 6.3e-11 41.8 0.2 1.3e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 CUE domain G2BR PF18442.1 CEP14405.1 - 0.014 15.0 7.4 0.014 15.0 7.4 2.7 3 0 0 3 3 3 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 CEP14405.1 - 0.041 13.9 8.7 0.095 12.8 5.5 2.7 2 1 0 2 2 2 0 Ubc7p-binding region of Cue1 DEAD PF00270.29 CEP14406.1 - 3.8e-45 153.8 0.5 1.1e-43 149.1 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP14406.1 - 1.3e-22 80.2 0.1 4.9e-21 75.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP14406.1 - 1.2e-08 35.1 0.6 1.1e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP14406.1 - 2.1e-08 33.7 0.0 4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CEP14406.1 - 0.0067 16.8 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP14406.1 - 0.013 15.8 0.1 0.057 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CEP14406.1 - 0.014 14.8 0.1 0.041 13.3 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein SecA_DEAD PF07517.14 CEP14406.1 - 0.078 12.3 0.1 0.23 10.7 0.1 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain CAAP1 PF15335.6 CEP14406.1 - 0.13 12.9 0.1 0.45 11.1 0.1 1.9 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 RRM_1 PF00076.22 CEP14407.1 - 2e-34 117.2 0.0 3.2e-14 52.5 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP14407.1 - 0.00022 21.3 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 CEP14407.1 - 0.00025 20.9 0.0 0.0096 15.8 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4290 PF14123.6 CEP14407.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) DUF1866 PF08952.11 CEP14407.1 - 0.026 14.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_9 PF18444.1 CEP14407.1 - 0.028 14.3 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM PF05172.13 CEP14407.1 - 0.19 11.7 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Apt1 PF10351.9 CEP14407.1 - 2.5 6.9 7.1 3.4 6.4 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AOX PF01786.17 CEP14409.1 - 3.3e-77 258.9 0.0 4.5e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase ABC_sub_bind PF04392.12 CEP14410.1 - 0.054 12.7 0.1 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein SAM_Exu PF18609.1 CEP14410.1 - 0.071 13.2 2.3 0.18 11.9 0.3 2.4 2 0 0 2 2 2 0 Exuperantia SAM-like domain LRR_4 PF12799.7 CEP14410.1 - 0.14 12.6 5.2 1.7 9.2 1.7 3.9 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 CEP14411.1 - 9.9e-14 50.7 0.1 1.9e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP14411.1 - 4.1e-08 33.0 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP14411.1 - 5.2e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP14411.1 - 0.00056 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_10 PF17902.1 CEP14411.1 - 0.0034 17.4 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF2070 PF09843.9 CEP14411.1 - 1.3 7.2 11.0 1.7 6.9 11.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2040 PF09745.9 CEP14412.1 - 1.4e-35 122.0 20.1 1.4e-35 122.0 20.1 4.3 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) ER_lumen_recept PF00810.18 CEP14413.1 - 2.8e-45 154.8 11.0 4.9e-45 154.0 11.0 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor cNMP_binding PF00027.29 CEP14413.1 - 7e-37 125.4 0.0 3.8e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CEP14413.1 - 6.1e-08 32.2 4.1 1.1e-07 31.3 4.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.6 CEP14414.1 - 3.3e-18 65.9 7.5 3.3e-14 53.1 3.3 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CEP14414.1 - 6e-17 59.9 8.0 7.4e-06 25.2 0.9 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CEP14414.1 - 1.8e-14 52.3 7.2 0.00021 21.0 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CEP14414.1 - 9.3e-11 40.7 3.7 8.7e-05 21.8 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEP14414.1 - 4.1e-06 26.6 11.7 0.00023 20.9 3.1 3.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CEP14414.1 - 5.7e-05 23.0 5.2 0.18 11.7 0.3 3.2 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEP14414.1 - 9.3e-05 22.7 6.6 0.085 13.2 0.2 3.5 2 2 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Haemagg_act PF05860.13 CEP14414.1 - 0.0016 18.3 0.7 3.2 7.6 0.0 3.2 1 1 1 2 2 2 2 haemagglutination activity domain Dockerin_1 PF00404.18 CEP14414.1 - 0.19 11.9 6.6 0.87 9.8 1.0 3.6 2 1 2 4 4 4 0 Dockerin type I domain zf-met PF12874.7 CEP14415.1 - 8.3e-11 41.9 77.9 0.017 15.5 0.6 11.4 11 0 0 11 11 11 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP14415.1 - 3.5e-07 30.4 89.8 0.012 15.9 1.8 10.8 11 0 0 11 11 11 8 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CEP14415.1 - 2.4 8.9 25.9 0.88 10.3 2.2 6.5 3 3 2 6 6 6 0 Zinc finger C2H2-type, 3 repeats HSF_DNA-bind PF00447.17 CEP14416.1 - 1.7e-29 102.2 0.8 4.8e-29 100.8 0.8 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding XPC-binding PF09280.11 CEP14416.1 - 0.016 14.9 1.6 0.049 13.4 1.6 1.8 1 0 0 1 1 1 0 XPC-binding domain DUF3135 PF11333.8 CEP14416.1 - 0.03 14.6 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF3917 PF13055.6 CEP14417.1 - 0.28 11.6 1.3 0.61 10.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) ANAPC4_WD40 PF12894.7 CEP14418.1 - 4.9e-05 23.5 0.0 0.00021 21.5 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Rotamase_3 PF13616.6 CEP14419.1 - 1.5e-15 57.7 0.1 4.2e-15 56.3 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CEP14419.1 - 2.1e-14 54.3 0.0 4e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF1018 PF06252.12 CEP14419.1 - 0.08 13.9 1.4 0.098 13.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) SUIM_assoc PF16619.5 CEP14420.1 - 0.8 9.8 9.6 0.16 12.0 4.8 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 MBD_C PF14048.6 CEP14421.1 - 1.1 10.1 5.5 1.4 9.7 2.2 2.1 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 SUR7 PF06687.12 CEP14422.1 - 9.1e-18 64.7 17.8 1.7e-17 63.8 18.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family Cadherin_C_2 PF16492.5 CEP14422.1 - 0.012 16.3 0.9 0.091 13.5 0.0 2.8 3 1 0 3 3 3 0 Cadherin cytoplasmic C-terminal Cyclin PF08613.11 CEP14423.1 - 2e-40 138.8 1.0 2.5e-40 138.5 1.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP14423.1 - 1e-05 25.3 0.1 1.3e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DER1 PF04511.15 CEP14423.1 - 0.046 13.6 1.3 0.058 13.3 1.3 1.2 1 0 0 1 1 1 0 Der1-like family MT-A70 PF05063.14 CEP14424.1 - 1.9e-38 132.1 0.0 2.6e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 CENP-B_N PF04218.13 CEP14424.1 - 0.045 13.4 0.2 0.082 12.6 0.2 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Cons_hypoth95 PF03602.15 CEP14424.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 P_C10 PF14974.6 CEP14425.1 - 0.086 12.9 0.1 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 Protein C10 Erf4 PF10256.9 CEP14425.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Ost5 PF05251.12 CEP14427.1 - 1.2e-14 54.3 6.2 1.3e-14 54.1 6.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TOM13 PF08219.11 CEP14428.1 - 1.5e-20 73.0 1.3 1.6e-20 72.9 0.3 1.5 2 0 0 2 2 2 1 Outer membrane protein TOM13 OrfB_Zn_ribbon PF07282.11 CEP14429.1 - 4.9e-10 39.2 0.1 1.3e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PH_6 PF15406.6 CEP14429.1 - 0.039 14.2 0.3 13 6.1 0.0 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain MMU163 PF17119.5 CEP14429.1 - 0.067 12.3 1.4 0.11 11.7 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Tropomyosin_1 PF12718.7 CEP14430.1 - 1e-15 58.1 23.2 1.7e-15 57.4 23.2 1.4 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CEP14430.1 - 2e-05 24.1 23.2 0.00016 21.1 22.3 2.0 1 1 0 1 1 1 1 Tropomyosin ATG16 PF08614.11 CEP14430.1 - 6.8e-05 23.2 18.7 0.0001 22.6 18.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CEP14430.1 - 8.8e-05 22.5 11.2 0.005 16.9 2.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) XhlA PF10779.9 CEP14430.1 - 0.0001 22.5 20.3 0.085 13.1 5.8 3.4 1 1 3 4 4 4 4 Haemolysin XhlA Laminin_I PF06008.14 CEP14430.1 - 0.00012 21.9 13.8 0.00017 21.4 13.8 1.3 1 0 0 1 1 1 1 Laminin Domain I DUF4201 PF13870.6 CEP14430.1 - 0.00013 21.7 7.2 0.00013 21.7 7.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Nup54 PF13874.6 CEP14430.1 - 0.00021 21.4 7.3 0.00021 21.4 7.3 1.8 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 CLZ PF16526.5 CEP14430.1 - 0.00026 21.3 18.6 0.12 12.7 2.3 3.1 1 1 2 3 3 3 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CEP14430.1 - 0.00033 20.9 12.6 0.058 13.6 3.9 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family EzrA PF06160.12 CEP14430.1 - 0.00036 18.9 19.3 0.00041 18.7 19.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SHE3 PF17078.5 CEP14430.1 - 0.00086 19.1 15.4 0.0012 18.6 15.4 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Laminin_II PF06009.12 CEP14430.1 - 0.00095 19.2 13.8 0.12 12.4 4.9 2.1 1 1 1 2 2 2 2 Laminin Domain II NPV_P10 PF05531.12 CEP14430.1 - 0.00096 19.6 7.7 0.2 12.1 0.9 2.7 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 CEP14430.1 - 0.001 19.1 10.1 0.0025 17.9 3.1 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF2730) Lebercilin PF15619.6 CEP14430.1 - 0.0011 18.6 21.9 0.0032 17.2 21.9 1.6 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease TolA_bind_tri PF16331.5 CEP14430.1 - 0.0013 18.8 9.8 0.063 13.4 0.1 2.7 1 1 1 2 2 2 1 TolA binding protein trimerisation Vps5 PF09325.10 CEP14430.1 - 0.0015 18.1 16.2 0.25 10.8 2.8 2.9 1 1 2 3 3 3 2 Vps5 C terminal like Prefoldin_2 PF01920.20 CEP14430.1 - 0.0016 18.3 25.1 0.37 10.8 5.4 3.2 1 1 2 3 3 3 1 Prefoldin subunit GAS PF13851.6 CEP14430.1 - 0.0016 17.8 23.7 0.0023 17.3 21.3 1.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CEP14430.1 - 0.0023 16.9 22.1 0.0044 15.9 22.1 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF745 PF05335.13 CEP14430.1 - 0.0025 17.6 8.4 0.0025 17.6 8.4 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF745) DUF3450 PF11932.8 CEP14430.1 - 0.0026 17.1 18.4 0.018 14.3 3.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF5082 PF16888.5 CEP14430.1 - 0.0028 17.9 13.9 0.031 14.6 1.9 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) IFT57 PF10498.9 CEP14430.1 - 0.0031 16.5 16.3 0.032 13.2 4.8 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Apolipoprotein PF01442.18 CEP14430.1 - 0.0038 17.1 17.6 0.013 15.4 17.5 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 CEP14430.1 - 0.0044 17.2 8.3 0.62 10.3 3.2 3.0 2 1 0 2 2 2 1 Proteins of 100 residues with WXG MscS_porin PF12795.7 CEP14430.1 - 0.007 16.0 16.8 1.9 8.0 0.2 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FliD_C PF07195.12 CEP14430.1 - 0.0078 15.7 11.7 0.2 11.0 11.7 2.4 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DHR10 PF18595.1 CEP14430.1 - 0.0094 16.0 23.1 0.016 15.2 20.4 2.0 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain GrpE PF01025.19 CEP14430.1 - 0.0097 15.6 4.7 0.0097 15.6 4.7 2.7 1 1 2 3 3 3 1 GrpE DUF16 PF01519.16 CEP14430.1 - 0.01 16.3 15.4 0.15 12.6 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 RmuC PF02646.16 CEP14430.1 - 0.012 14.7 11.0 0.33 10.0 1.9 2.1 1 1 1 2 2 2 0 RmuC family DUF4407 PF14362.6 CEP14430.1 - 0.013 14.9 12.5 0.014 14.7 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EURL PF06937.11 CEP14430.1 - 0.014 14.8 7.8 0.018 14.5 7.8 1.1 1 0 0 1 1 1 0 EURL protein TMF_DNA_bd PF12329.8 CEP14430.1 - 0.016 15.2 27.2 0.39 10.7 14.3 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 CEP14430.1 - 0.016 15.4 10.9 0.016 15.4 10.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SbsC_C PF18058.1 CEP14430.1 - 0.019 15.2 9.5 0.016 15.4 7.8 1.6 1 1 1 2 2 2 0 SbsC C-terminal domain Sec34 PF04136.15 CEP14430.1 - 0.023 14.6 11.0 0.58 10.0 6.1 2.2 1 1 1 2 2 2 0 Sec34-like family ABC_tran_CTD PF16326.5 CEP14430.1 - 0.023 14.9 25.6 3.2 8.1 5.0 3.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain FPP PF05911.11 CEP14430.1 - 0.024 12.8 21.3 0.026 12.7 21.3 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF641 PF04859.12 CEP14430.1 - 0.025 14.9 15.8 0.073 13.4 6.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CCDC144C PF14915.6 CEP14430.1 - 0.025 13.7 19.8 0.075 12.1 19.8 1.7 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region MAD PF05557.13 CEP14430.1 - 0.027 12.9 20.1 0.032 12.6 20.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ERM PF00769.19 CEP14430.1 - 0.03 14.2 22.3 0.012 15.5 19.3 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prok-TraM PF09228.10 CEP14430.1 - 0.032 14.6 8.2 0.45 10.9 2.0 2.1 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Taxilin PF09728.9 CEP14430.1 - 0.032 13.4 22.6 0.038 13.2 22.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Jnk-SapK_ap_N PF09744.9 CEP14430.1 - 0.034 14.4 21.2 0.048 13.9 21.2 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ADIP PF11559.8 CEP14430.1 - 0.037 14.1 17.5 0.061 13.4 16.2 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 CEP14430.1 - 0.037 14.4 17.9 1.2 9.6 2.1 3.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 CEP14430.1 - 0.038 13.8 23.1 1.2 8.9 11.6 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 CEP14430.1 - 0.041 14.3 24.9 0.58 10.6 24.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.15 CEP14430.1 - 0.041 13.7 23.7 0.51 10.2 2.1 3.1 1 1 2 3 3 3 0 Septum formation initiator Cortex-I_coil PF09304.10 CEP14430.1 - 0.046 13.9 17.1 0.038 14.2 8.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF2968 PF11180.8 CEP14430.1 - 0.048 13.3 12.7 0.37 10.4 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Baculo_PEP_C PF04513.12 CEP14430.1 - 0.053 13.6 7.2 0.1 12.6 3.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 CEP14430.1 - 0.055 13.5 22.1 0.96 9.5 22.1 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CEP14430.1 - 0.068 11.8 17.5 0.11 11.1 17.5 1.4 1 1 0 1 1 1 0 AAA domain Uso1_p115_C PF04871.13 CEP14430.1 - 0.085 13.2 24.8 0.14 12.5 13.3 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2959 PF11172.8 CEP14430.1 - 0.087 13.0 10.6 0.22 11.6 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DUF4472 PF14739.6 CEP14430.1 - 0.095 13.4 17.1 0.59 10.9 5.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF2353 PF09789.9 CEP14430.1 - 0.095 12.0 15.8 0.11 11.9 15.8 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF812 PF05667.11 CEP14430.1 - 0.097 11.5 19.9 0.7 8.7 19.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.8 CEP14430.1 - 0.1 10.1 16.1 0.12 9.9 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 CEP14430.1 - 0.12 12.9 12.1 0.71 10.3 11.3 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4735 PF15882.5 CEP14430.1 - 0.12 11.8 2.1 0.15 11.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) BLOC1_2 PF10046.9 CEP14430.1 - 0.12 12.7 15.9 2.4 8.5 4.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 CEP14430.1 - 0.12 12.2 18.4 0.2 11.5 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 CEP14430.1 - 0.13 12.8 18.2 0.4 11.1 18.2 1.7 1 1 0 1 1 1 0 Fez1 HemX PF04375.14 CEP14430.1 - 0.13 11.5 14.4 0.087 12.1 6.5 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Golgin_A5 PF09787.9 CEP14430.1 - 0.14 11.5 18.7 0.18 11.2 18.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 CEP14430.1 - 0.15 11.6 16.5 0.39 10.3 16.5 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 CEP14430.1 - 0.15 12.1 19.7 0.23 11.6 19.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ExsD PF16806.5 CEP14430.1 - 0.17 11.8 7.8 0.26 11.2 7.8 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD PI3K_P85_iSH2 PF16454.5 CEP14430.1 - 0.18 11.4 15.8 0.47 10.0 15.8 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HOOK PF05622.12 CEP14430.1 - 0.2 9.7 20.7 0.24 9.5 20.7 1.0 1 0 0 1 1 1 0 HOOK protein DUF948 PF06103.11 CEP14430.1 - 0.2 11.9 7.9 2.9 8.2 1.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CC2-LZ PF16516.5 CEP14430.1 - 0.21 12.0 17.7 1.1 9.6 6.2 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Striatin PF08232.12 CEP14430.1 - 0.22 12.1 13.2 0.31 11.6 13.2 1.3 1 0 0 1 1 1 0 Striatin family KLRAQ PF10205.9 CEP14430.1 - 0.23 11.7 16.8 0.19 12.0 9.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1759 PF03564.15 CEP14430.1 - 0.23 11.4 5.2 0.77 9.7 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) CENP-F_leu_zip PF10473.9 CEP14430.1 - 0.24 11.4 23.9 0.21 11.6 15.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 CEP14430.1 - 0.25 10.9 11.4 0.29 10.7 11.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TACC_C PF05010.14 CEP14430.1 - 0.25 11.1 19.4 0.68 9.7 4.1 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 CEP14430.1 - 0.27 11.9 15.6 2.8 8.6 4.2 3.1 1 1 2 3 3 3 0 SlyX Myb_DNA-bind_3 PF12776.7 CEP14430.1 - 0.27 12.2 5.8 1.1 10.3 0.3 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Cob_adeno_trans PF01923.18 CEP14430.1 - 0.28 11.3 6.5 0.63 10.2 6.3 1.7 1 1 0 1 1 1 0 Cobalamin adenosyltransferase YlqD PF11068.8 CEP14430.1 - 0.29 11.5 15.6 0.042 14.2 9.0 2.3 1 1 1 2 2 2 0 YlqD protein Dynactin_p22 PF07426.11 CEP14430.1 - 0.31 10.9 13.8 1.2 8.9 3.2 2.5 1 1 1 2 2 2 0 Dynactin subunit p22 FapA PF03961.13 CEP14430.1 - 0.33 9.5 17.3 0.58 8.7 11.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Ly49 PF08391.10 CEP14430.1 - 0.33 11.3 9.1 1.6 9.1 9.1 1.9 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Rootletin PF15035.6 CEP14430.1 - 0.37 10.8 16.9 0.87 9.6 8.8 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TTKRSYEDQ PF10212.9 CEP14430.1 - 0.38 9.7 9.7 0.45 9.5 9.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein AKNA PF12443.8 CEP14430.1 - 0.38 11.4 11.4 3.9 8.2 0.7 3.1 1 1 2 3 3 3 0 AT-hook-containing transcription factor FliJ PF02050.16 CEP14430.1 - 0.39 10.9 16.5 0.8 9.9 9.1 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Occludin_ELL PF07303.13 CEP14430.1 - 0.41 11.4 12.6 6.5 7.5 8.9 2.7 1 1 0 2 2 2 0 Occludin homology domain HrpB7 PF09486.10 CEP14430.1 - 0.41 11.0 12.6 4 7.8 12.6 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Fmp27_WPPW PF10359.9 CEP14430.1 - 0.41 9.4 14.8 3.2 6.5 14.8 1.9 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.22 CEP14430.1 - 0.41 10.9 21.1 1.7 8.9 5.7 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CREPT PF16566.5 CEP14430.1 - 0.44 10.7 14.7 1.3 9.2 7.1 2.7 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CALCOCO1 PF07888.11 CEP14430.1 - 0.46 9.3 20.2 0.5 9.2 20.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4795 PF16043.5 CEP14430.1 - 0.46 10.1 18.8 13 5.3 18.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Atg14 PF10186.9 CEP14430.1 - 0.47 9.5 15.1 5 6.1 15.1 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4315 PF14193.6 CEP14430.1 - 0.48 10.5 21.1 0.97 9.5 2.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Cep57_MT_bd PF06657.13 CEP14430.1 - 0.5 10.9 15.5 1.1 9.7 5.7 3.0 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2802 PF10975.8 CEP14430.1 - 0.52 10.5 11.5 27 5.0 4.6 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) TMPIT PF07851.13 CEP14430.1 - 0.52 9.5 14.7 0.17 11.1 7.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein BST2 PF16716.5 CEP14430.1 - 0.52 10.9 20.4 0.88 10.2 4.7 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 CEP14430.1 - 0.53 10.4 19.9 0.27 11.3 9.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Prefoldin PF02996.17 CEP14430.1 - 0.57 10.1 19.1 0.43 10.5 2.9 3.1 1 1 1 3 3 3 0 Prefoldin subunit HMMR_N PF15905.5 CEP14430.1 - 0.58 9.6 22.8 0.73 9.2 22.8 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DASH_Spc34 PF08657.10 CEP14430.1 - 0.59 9.9 11.1 1.1 9.0 9.7 1.9 1 1 1 2 2 2 0 DASH complex subunit Spc34 FemAB PF02388.16 CEP14430.1 - 0.59 8.9 15.4 0.044 12.7 6.7 1.9 1 1 1 2 2 2 0 FemAB family Nnf1 PF03980.14 CEP14430.1 - 0.6 10.5 17.1 0.34 11.3 7.8 2.5 1 1 1 2 2 2 0 Nnf1 Alanine_zipper PF11839.8 CEP14430.1 - 0.67 10.4 6.9 2.8 8.4 0.7 2.8 1 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein BRE1 PF08647.11 CEP14430.1 - 0.68 10.0 21.5 0.8 9.8 9.0 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase FH2 PF02181.23 CEP14430.1 - 0.76 8.8 13.2 0.33 10.0 7.0 1.8 1 1 1 2 2 2 0 Formin Homology 2 Domain 60KD_IMP PF02096.20 CEP14430.1 - 0.92 9.4 8.8 0.19 11.6 1.0 2.5 1 1 2 3 3 2 0 60Kd inner membrane protein Noelin-1 PF12308.8 CEP14430.1 - 1.3 9.1 7.8 6.7 6.8 2.4 2.5 1 1 2 3 3 3 0 Neurogenesis glycoprotein Csm1_N PF18504.1 CEP14430.1 - 1.3 9.4 20.9 1.4 9.3 3.3 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain Tektin PF03148.14 CEP14430.1 - 1.4 7.6 19.6 5.1 5.7 2.4 2.6 1 1 0 1 1 1 0 Tektin family OmpH PF03938.14 CEP14430.1 - 1.5 9.2 22.8 4.9 7.5 5.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TMEM95 PF15203.6 CEP14430.1 - 1.5 8.5 3.6 1 9.0 0.9 1.8 1 1 1 2 2 2 0 TMEM95 family AAA_11 PF13086.6 CEP14430.1 - 1.5 8.5 10.5 2.1 8.1 10.5 1.2 1 0 0 1 1 1 0 AAA domain DUF1515 PF07439.11 CEP14430.1 - 1.6 8.8 7.9 7.8 6.6 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Lectin_N PF03954.14 CEP14430.1 - 1.6 8.5 8.3 0.5 10.1 2.6 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain PRKCSH-like PF12999.7 CEP14430.1 - 1.6 8.5 11.0 0.47 10.2 4.9 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Prominin PF05478.11 CEP14430.1 - 1.6 6.6 9.5 1.9 6.3 9.5 1.2 1 0 0 1 1 1 0 Prominin HAUS6_N PF14661.6 CEP14430.1 - 1.6 8.2 12.9 2.1 7.8 8.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Vac_Fusion PF02346.16 CEP14430.1 - 1.6 8.4 6.5 2.7 7.7 0.6 2.9 1 1 3 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF4298 PF14131.6 CEP14430.1 - 1.8 8.6 14.0 5.8 7.0 0.2 3.2 1 1 1 2 2 1 0 Domain of unknown function (DUF4298) Spc24 PF08286.11 CEP14430.1 - 1.9 8.8 20.5 4.7 7.5 2.6 3.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 CEP14430.1 - 1.9 8.6 18.2 7.3 6.8 1.8 3.4 1 1 2 3 3 3 0 Swi5 V_ATPase_I PF01496.19 CEP14430.1 - 1.9 6.3 12.3 2.3 6.0 12.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.9 CEP14430.1 - 2.1 8.3 21.3 4.6 7.1 3.9 2.9 1 1 1 2 2 2 0 Axonemal dynein light chain Fzo_mitofusin PF04799.13 CEP14430.1 - 2.2 7.8 12.3 0.9 9.1 6.0 2.5 1 1 2 3 3 3 0 fzo-like conserved region FAM76 PF16046.5 CEP14430.1 - 2.5 7.4 17.3 0.52 9.6 8.4 2.0 1 1 1 2 2 2 0 FAM76 protein P4Ha_N PF08336.11 CEP14430.1 - 2.7 8.0 15.6 0.12 12.4 2.9 2.9 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KxDL PF10241.9 CEP14430.1 - 2.8 8.3 12.6 4.2 7.7 3.4 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein bZIP_1 PF00170.21 CEP14430.1 - 2.8 8.1 23.9 0.37 10.9 2.5 4.1 1 1 4 5 5 5 0 bZIP transcription factor IZUMO PF15005.6 CEP14430.1 - 3.1 8.3 10.1 3.6 8.1 10.1 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF4250 PF14056.6 CEP14430.1 - 3.1 7.8 6.1 13 5.9 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) GreA_GreB_N PF03449.15 CEP14430.1 - 4 7.7 16.9 0.8 9.9 8.2 3.2 1 1 2 3 3 3 0 Transcription elongation factor, N-terminal TFR_dimer PF04253.15 CEP14430.1 - 4 7.6 11.3 6.3 6.9 1.3 2.4 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain Lipoprotein_20 PF13942.6 CEP14430.1 - 4.1 7.3 12.5 3.2 7.7 7.3 2.0 1 1 1 2 2 2 0 YfhG lipoprotein DUF4446 PF14584.6 CEP14430.1 - 4.1 7.4 13.0 9.5 6.2 4.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Rho_Binding PF08912.11 CEP14430.1 - 4.2 8.3 24.1 3.2 8.6 5.5 3.4 1 1 2 3 3 3 0 Rho Binding CEP209_CC5 PF16574.5 CEP14430.1 - 4.5 7.5 22.5 3.5 7.8 4.0 2.1 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF1043 PF06295.12 CEP14430.1 - 5.1 7.1 13.4 17 5.4 13.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) ZapB PF06005.12 CEP14430.1 - 6.2 7.3 26.3 1.8e+04 -6.8 26.3 3.1 1 1 0 1 1 0 0 Cell division protein ZapB APG6_N PF17675.1 CEP14430.1 - 6.3 7.3 27.1 3.8e+02 1.6 27.1 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Tup_N PF08581.10 CEP14430.1 - 6.4 7.2 17.4 10 6.5 7.7 2.3 1 1 1 2 2 2 0 Tup N-terminal RRP36 PF06102.12 CEP14430.1 - 8 6.4 16.5 13 5.7 16.5 1.5 1 1 0 1 1 1 0 rRNA biogenesis protein RRP36 THOC7 PF05615.13 CEP14430.1 - 8.4 6.7 18.0 7.8e+02 0.3 18.0 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 5_nucleotid PF05761.14 CEP14430.1 - 8.8 5.1 11.5 3.3 6.5 8.3 1.7 1 1 1 2 2 2 0 5' nucleotidase family Phage_GPO PF05929.11 CEP14430.1 - 8.9 5.8 13.6 28 4.2 13.6 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GST_N_2 PF13409.6 CEP14431.1 - 7.5e-21 74.2 0.0 1.6e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEP14431.1 - 2e-12 46.9 0.0 5.7e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP14431.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CEP14431.1 - 1.1e-06 28.8 0.3 2.9e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEP14431.1 - 0.0061 17.0 0.0 0.077 13.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RGI1 PF10843.8 CEP14431.1 - 0.021 14.5 0.2 0.049 13.3 0.2 1.6 1 0 0 1 1 1 0 Respiratory growth induced protein 1 GST_C_6 PF17171.4 CEP14431.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fasciclin PF02469.22 CEP14432.1 - 1.5e-79 264.5 0.0 2.5e-20 73.0 0.0 5.2 5 0 0 5 5 5 5 Fasciclin domain AA_permease_2 PF13520.6 CEP14433.1 - 3.5e-63 213.9 52.9 4.3e-63 213.6 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP14433.1 - 6.6e-24 84.3 42.7 9.6e-24 83.8 42.7 1.2 1 0 0 1 1 1 1 Amino acid permease RAMP4 PF06624.12 CEP14433.1 - 0.11 12.6 0.5 8.7 6.5 0.3 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 SPRY PF00622.28 CEP14434.1 - 2.1e-15 56.9 0.0 4.2e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.6 CEP14434.1 - 2.5e-05 24.1 0.1 8.3e-05 22.4 0.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP14434.1 - 0.0049 16.7 1.4 0.02 14.7 0.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4534 PF15049.6 CEP14434.1 - 0.023 14.4 0.1 0.05 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) Peptidase_S8 PF00082.22 CEP14435.1 - 1.6e-32 113.0 5.9 2.4e-32 112.4 5.6 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEP14435.1 - 0.043 14.5 1.6 0.091 13.4 1.6 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I9 adh_short PF00106.25 CEP14437.1 - 5.8e-57 192.3 1.5 6.9e-57 192.1 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP14437.1 - 3.1e-43 148.0 0.8 3.7e-43 147.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP14437.1 - 3.3e-14 53.2 0.6 4.4e-14 52.8 0.6 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEP14437.1 - 3.9e-06 26.2 1.2 6.1e-06 25.6 1.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CEP14437.1 - 8e-05 22.2 0.1 0.00017 21.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEP14437.1 - 0.00029 20.8 1.4 0.00038 20.4 1.4 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Prot_ATP_OB_N PF17758.1 CEP14437.1 - 0.03 14.0 0.6 1.2 8.9 0.3 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain 3HCDH_N PF02737.18 CEP14437.1 - 0.031 14.2 0.5 0.047 13.6 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GatB_Yqey PF02637.18 CEP14437.1 - 0.037 13.9 0.3 0.068 13.1 0.3 1.4 1 0 0 1 1 1 0 GatB domain GDP_Man_Dehyd PF16363.5 CEP14437.1 - 0.12 11.8 0.1 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UCH PF00443.29 CEP14438.1 - 8.1e-41 140.2 4.0 7.4e-25 87.9 0.1 2.3 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP14438.1 - 2e-09 37.5 5.9 3.9e-09 36.5 5.9 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ZapB PF06005.12 CEP14438.1 - 0.017 15.5 4.1 0.017 15.5 4.1 2.7 2 0 0 2 2 2 0 Cell division protein ZapB RNA_pol_Rpb1_1 PF04997.12 CEP14438.1 - 0.35 10.1 4.0 1.2 8.4 4.0 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Spc24 PF08286.11 CEP14438.1 - 0.4 10.9 3.7 0.19 12.0 0.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ribosomal_L38e PF01781.18 CEP14439.1 - 2.2e-35 120.6 3.6 2.4e-35 120.4 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 CEP14439.1 - 0.026 14.8 0.2 0.031 14.5 0.2 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain CRF PF00473.17 CEP14439.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family CLTH PF10607.9 CEP14440.1 - 1.1e-19 70.8 0.1 1.3e-19 70.6 0.1 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BORCS7 PF16088.5 CEP14441.1 - 2.7e-17 62.9 3.2 3.6e-17 62.5 3.2 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 MapZ_EC1 PF18041.1 CEP14441.1 - 0.34 11.2 4.8 0.31 11.3 3.3 1.6 1 1 1 2 2 2 0 MapZ extracellular domain 1 W2 PF02020.18 CEP14442.1 - 1.5e-10 41.1 6.3 1.5e-10 41.1 6.3 2.6 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Tmemb_cc2 PF10267.9 CEP14442.1 - 0.0011 18.3 1.2 0.0011 18.3 1.2 2.1 2 1 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein UPF0242 PF06785.11 CEP14442.1 - 0.0011 19.1 2.4 0.0011 19.1 2.4 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 CEP14442.1 - 0.077 13.2 0.9 0.26 11.5 0.9 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CEP14442.1 - 0.081 13.4 0.5 0.57 10.7 0.5 2.4 1 1 0 1 1 1 0 Cell division protein ZapB PRKG1_interact PF15898.5 CEP14442.1 - 0.62 11.0 9.2 0.95 10.4 0.1 3.1 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain WRNPLPNID PF15017.6 CEP14442.1 - 4.5 8.2 21.2 19 6.2 5.8 3.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Prp18 PF02840.15 CEP14444.1 - 6.6e-60 201.3 0.4 6.6e-60 201.3 0.4 2.4 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CEP14444.1 - 6.4e-10 38.4 0.4 6.4e-10 38.4 0.4 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF3536 PF12055.8 CEP14444.1 - 0.0075 15.6 0.1 0.03 13.7 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3536) AvrPphF-ORF-2 PF09143.10 CEP14444.1 - 0.078 12.9 0.8 0.39 10.6 0.2 2.2 2 1 0 2 2 2 0 AvrPphF-ORF-2 QIL1 PF15884.5 CEP14444.1 - 0.34 11.5 1.7 27 5.5 0.0 3.1 2 1 1 3 3 3 0 MICOS complex subunit MIC13, QIL1 RVT_1 PF00078.27 CEP14445.1 - 1.8e-15 57.1 0.0 2.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP14445.1 - 1.2e-07 32.3 0.2 2.7e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GDPD PF03009.17 CEP14446.1 - 8.1e-28 97.8 0.0 1.8e-27 96.7 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 CEP14446.1 - 0.00064 20.1 1.2 0.0017 18.8 1.2 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family E3_UFM1_ligase PF09743.9 CEP14447.1 - 6.2e-21 75.2 1.1 2.7e-20 73.1 0.6 2.2 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 F-box PF00646.33 CEP14447.1 - 0.0091 15.9 0.0 0.04 13.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP14447.1 - 0.012 15.5 0.1 0.034 14.0 0.1 1.8 1 0 0 1 1 1 0 F-box-like SH3_1 PF00018.28 CEP14448.1 - 8.6e-12 44.5 0.0 1.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP14448.1 - 5.1e-09 35.7 0.0 1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP14448.1 - 2.9e-07 30.2 0.0 4.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CEP14448.1 - 0.033 14.5 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_4 PF06347.13 CEP14448.1 - 0.045 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_10 PF17902.1 CEP14448.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 SH3 domain Ras PF00071.22 CEP14450.1 - 9.3e-53 178.1 0.0 1.6e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Ras family FA_desaturase PF00487.24 CEP14450.1 - 9.7e-42 143.5 8.4 1.6e-41 142.8 8.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Roc PF08477.13 CEP14450.1 - 2.7e-29 101.8 0.0 6.7e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cyt-b5 PF00173.28 CEP14450.1 - 2.2e-13 50.1 0.2 7.9e-13 48.4 0.2 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.21 CEP14450.1 - 3.8e-10 39.5 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP14450.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1475 PF07343.11 CEP14450.1 - 0.036 13.9 1.0 0.077 12.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) PduV-EutP PF10662.9 CEP14450.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CEP14450.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEP14450.1 - 0.16 12.0 0.2 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEP14450.1 - 0.18 11.7 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Ydc2-catalyt PF09159.10 CEP14451.1 - 1.4e-25 90.6 4.5 3.8e-13 49.8 0.1 3.1 1 1 2 3 3 3 3 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 CEP14451.1 - 1.3e-06 28.0 0.0 3.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 CEP14451.1 - 0.0012 18.7 0.7 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Pox_A22 PF04848.13 CEP14451.1 - 0.0044 17.1 0.1 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A22 protein Cir_N PF10197.9 CEP14451.1 - 0.48 10.7 0.0 0.48 10.7 0.0 3.0 4 0 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR RPE65 PF03055.15 CEP14452.1 - 1.2e-89 301.6 0.6 1.6e-89 301.3 0.6 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4813 PF16072.5 CEP14453.1 - 0.32 10.6 10.2 0.39 10.3 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DnaJ_C PF01556.18 CEP14454.1 - 3.6e-35 121.2 0.1 5.9e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP14454.1 - 8.7e-21 73.8 1.9 8.7e-21 73.8 1.9 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP14454.1 - 2.2e-15 56.7 14.4 4e-15 55.9 14.4 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEP14454.1 - 1e-05 25.4 4.6 0.067 13.2 0.4 2.7 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CEP14454.1 - 5 7.2 9.2 9.5 6.3 9.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 CEP14454.1 - 8.4 6.9 10.1 0.89 10.0 1.6 3.0 2 1 1 3 3 3 0 Restriction alleviation protein Lar Amidohydro_1 PF01979.20 CEP14455.1 - 1.5e-06 27.8 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP14455.1 - 5.5e-05 22.8 0.0 6.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family ComZ PF10815.8 CEP14455.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 ComZ Metallophos PF00149.28 CEP14457.1 - 1.5e-39 136.6 0.1 2.6e-39 135.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ANAPC10 PF03256.16 CEP14457.1 - 3e-39 134.6 0.2 5.3e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) STPPase_N PF16891.5 CEP14457.1 - 1.2e-22 80.1 0.9 3.4e-22 78.6 0.3 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain IL22 PF14565.6 CEP14459.1 - 0.06 13.6 0.6 1.2 9.4 0.0 2.1 1 1 1 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor OrfB_Zn_ribbon PF07282.11 CEP14460.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Y_phosphatase PF00102.27 CEP14461.1 - 3.5e-07 30.1 0.0 0.00014 21.6 0.0 2.0 1 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CEP14461.1 - 4e-05 23.4 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CEP14461.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate SAM_2 PF07647.17 CEP14462.1 - 1.1e-07 31.9 0.2 2.7e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP14462.1 - 3.7e-05 24.1 0.1 9.6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MTHFR PF02219.17 CEP14463.1 - 8e-107 356.8 0.0 1.1e-106 356.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_25 PF13649.6 CEP14464.1 - 4.5e-10 40.1 0.0 1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP14464.1 - 2.5e-08 34.0 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP14464.1 - 5.1e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP14464.1 - 7.5e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP14464.1 - 1.7e-05 24.4 0.2 0.00038 20.0 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_12 PF08242.12 CEP14464.1 - 0.00014 22.5 0.0 0.00059 20.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP14464.1 - 0.00027 20.4 0.0 0.00085 18.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Ribosomal_S8 PF00410.19 CEP14464.1 - 0.0068 16.3 0.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S8 Methyltransf_8 PF05148.15 CEP14464.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase SWIM PF04434.17 CEP14465.1 - 0.0049 16.5 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger MULE PF10551.9 CEP14465.1 - 0.043 14.2 0.4 0.3 11.5 0.2 2.4 2 0 0 2 2 2 0 MULE transposase domain Lsr2 PF11774.8 CEP14465.1 - 0.1 12.8 1.1 0.28 11.4 0.1 2.4 3 1 0 3 3 3 0 Lsr2 NRDD PF13597.6 CEP14467.1 - 0.00015 20.7 0.0 0.00026 19.9 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase FOXP-CC PF16159.5 CEP14467.1 - 0.065 13.9 0.1 19 6.0 0.0 3.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Frag1 PF10277.9 CEP14470.1 - 3.6e-37 128.0 15.2 3.6e-37 128.0 15.2 3.3 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF4244 PF14029.6 CEP14470.1 - 0.61 9.6 2.2 14 5.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) zf-3CxxC_2 PF17180.4 CEP14471.1 - 1.7e-10 41.5 8.1 5.8e-10 39.8 8.1 1.9 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC PF13695.6 CEP14471.1 - 2.3 8.7 14.3 1.4e+02 3.0 14.3 2.9 1 1 0 1 1 1 0 Zinc-binding domain Fer4_10 PF13237.6 CEP14471.1 - 2.4 8.3 10.6 1.7 8.8 7.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain PI3Ka PF00613.20 CEP14473.1 - 9.2e-59 197.9 0.1 1.6e-58 197.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CEP14473.1 - 3.5e-51 174.4 0.0 6.5e-35 121.1 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CEP14473.1 - 3.9e-39 133.8 0.1 9.4e-39 132.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CEP14473.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) NMO PF03060.15 CEP14474.1 - 7e-57 193.3 0.6 1.9e-55 188.6 0.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CEP14474.1 - 2.8e-12 46.3 0.1 3.2e-09 36.3 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 CEP14474.1 - 0.00029 20.1 0.6 0.0057 15.9 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 CEP14474.1 - 0.0034 16.5 0.5 0.0075 15.3 0.5 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CEP14474.1 - 0.033 13.6 0.4 0.38 10.2 0.1 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 CEP14474.1 - 0.042 13.0 1.1 0.071 12.2 0.7 1.7 2 1 0 2 2 2 0 Conserved region in glutamate synthase GCR1_C PF12550.8 CEP14475.1 - 2.2e-09 37.5 0.1 3.4e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Caskin-tail PF16632.5 CEP14475.1 - 1.7 9.1 5.9 0.76 10.2 0.6 2.3 2 0 0 2 2 2 0 C-terminal region of Caskin NDC10_II PF16787.5 CEP14476.1 - 3.8e-41 141.2 0.0 1.3e-33 116.4 0.0 2.1 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 ydhR PF08803.11 CEP14481.1 - 0.095 12.6 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR DDE_3 PF13358.6 CEP14482.1 - 7.3e-09 35.5 0.0 8.8e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PepSY_2 PF13670.6 CEP14484.1 - 1.3e-06 28.2 0.6 8.5 6.5 0.0 5.9 3 1 2 5 5 5 3 Peptidase propeptide and YPEB domain DUF1233 PF06806.12 CEP14484.1 - 0.025 14.2 24.0 14 5.4 0.2 7.1 7 0 0 7 7 7 0 Putative excisionase (DUF1233) EF-hand_like PF09279.11 CEP14484.1 - 0.14 12.6 0.2 0.3 11.6 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2753 PF10952.8 CEP14486.1 - 0.07 13.3 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) GATA PF00320.27 CEP14487.1 - 8.4e-15 54.1 3.7 8.4e-15 54.1 3.7 2.0 2 0 0 2 2 2 1 GATA zinc finger Lzipper-MIP1 PF14389.6 CEP14487.1 - 0.0074 16.6 0.4 0.023 15.0 0.4 1.9 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 TF_Zn_Ribbon PF08271.12 CEP14487.1 - 0.04 13.4 0.9 0.098 12.2 0.9 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RRN7 PF11781.8 CEP14487.1 - 0.23 11.2 0.8 0.57 9.9 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 CEP14487.1 - 1.2 9.3 4.3 0.44 10.7 0.9 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Asn_synthase PF00733.21 CEP14488.1 - 4.1e-97 326.0 0.2 5.1e-59 200.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CEP14488.1 - 4.5e-39 133.1 0.0 9.1e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEP14488.1 - 1.6e-32 112.5 0.0 3.4e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEP14488.1 - 8.6e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CEP14488.1 - 0.0039 16.4 0.1 0.015 14.5 0.0 2.1 2 1 0 2 2 2 1 NAD synthase QueC PF06508.13 CEP14488.1 - 0.08 12.4 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PepSY_2 PF13670.6 CEP14489.1 - 0.0032 17.4 0.1 4.3 7.4 0.0 3.4 2 1 1 3 3 3 2 Peptidase propeptide and YPEB domain SASP_gamma PF04259.14 CEP14489.1 - 0.017 15.6 0.4 0.17 12.4 0.0 2.5 2 1 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type DUF1233 PF06806.12 CEP14489.1 - 4.3 7.0 16.0 5.6 6.6 0.1 4.4 5 1 0 5 5 5 0 Putative excisionase (DUF1233) UDPGT PF00201.18 CEP14491.1 - 0.0059 15.5 0.1 0.33 9.7 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Sec63 PF02889.16 CEP14492.1 - 1.1e-26 93.5 0.0 5.1e-26 91.4 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 CEP14492.1 - 1.3e-20 73.3 0.8 3.1e-20 72.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain RXT2_N PF08595.11 CEP14492.1 - 0.44 10.6 0.1 0.44 10.6 0.1 3.3 3 1 0 3 3 3 0 RXT2-like, N-terminal SH3_1 PF00018.28 CEP14493.1 - 2.3e-12 46.3 0.0 5.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PX PF00787.24 CEP14493.1 - 3.5e-07 30.2 0.0 7.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CEP14493.1 - 3.5e-05 23.6 0.0 9.6e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain PDGF_N PF04692.13 CEP14493.1 - 2.5 9.0 5.3 0.52 11.1 0.9 2.0 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Rho_GDI PF02115.17 CEP14494.1 - 2e-43 148.4 1.4 1.2e-25 90.4 0.2 2.0 1 1 1 2 2 2 2 RHO protein GDP dissociation inhibitor RXLR PF16810.5 CEP14496.1 - 0.045 14.2 0.3 0.05 14.0 0.3 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Es2 PF09751.9 CEP14498.1 - 4.1e-66 224.5 16.6 2.9e-47 162.4 7.3 2.9 2 1 1 3 3 3 2 Nuclear protein Es2 DUF1729 PF08354.10 CEP14499.1 - 3.2e-148 493.3 0.0 5.5e-148 492.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 CEP14499.1 - 1.3e-127 422.3 1.0 2.8e-63 213.1 0.1 2.7 2 0 0 2 2 2 2 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 CEP14499.1 - 6.1e-69 232.9 0.0 1.7e-68 231.5 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain FAS_I_H PF18314.1 CEP14499.1 - 2e-65 220.3 0.0 4.1e-65 219.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 CEP14499.1 - 6e-44 149.4 0.1 1.5e-43 148.1 0.1 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 CEP14499.1 - 7.2e-30 103.1 0.0 2.5e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 CEP14499.1 - 3.1e-28 99.1 0.0 8.9e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 CEP14499.1 - 1.8e-23 82.9 2.0 5e-23 81.5 2.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta ketoacyl-synt PF00109.26 CEP14499.1 - 2.6e-19 69.8 0.2 1e-18 67.8 0.2 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CEP14499.1 - 6.5e-16 58.5 0.0 1.8e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 CEP14499.1 - 1.7e-15 57.3 0.0 7.2e-15 55.3 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Ketoacyl-synt_C PF02801.22 CEP14499.1 - 2.1e-10 40.7 0.0 6.4e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Sulfotransfer_4 PF17784.1 CEP14499.1 - 0.02 14.7 0.0 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 Sulfotransferase domain DDE_3 PF13358.6 CEP14500.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease LegC3_N PF18654.1 CEP14501.1 - 0.059 12.6 4.5 0.081 12.2 4.5 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain DUF2009 PF09418.10 CEP14501.1 - 0.079 12.0 0.8 0.1 11.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Rieske PF00355.26 CEP14502.1 - 7.3e-12 45.1 0.0 1.6e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CEP14502.1 - 2.8e-11 43.7 2.0 7.8e-11 42.3 0.6 2.4 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Transp_cyt_pur PF02133.15 CEP14502.1 - 0.11 11.3 0.2 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1691 PF07950.11 CEP14503.1 - 7.4e-20 71.7 0.4 2.5e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 CEP14503.1 - 0.00038 20.5 0.2 0.00038 20.5 0.2 2.5 1 1 1 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SecY PF00344.20 CEP14504.1 - 1.7e-69 234.4 10.8 2.2e-69 234.1 10.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CEP14504.1 - 1.7e-17 63.0 0.5 4.1e-17 61.7 0.5 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p DUF4395 PF14340.6 CEP14504.1 - 1.5 9.1 5.7 1.6 9.1 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) CxC2 PF18803.1 CEP14505.1 - 3.8e-06 27.0 0.4 7e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Polysacc_deac_1 PF01522.21 CEP14507.1 - 1.4e-22 79.9 0.0 3.1e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Rxt3 PF08642.10 CEP14508.1 - 1.1 10.0 4.0 0.69 10.7 0.8 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 GWT1 PF06423.12 CEP14509.1 - 1.1e-36 126.2 5.0 1.1e-36 126.2 5.0 2.8 2 1 1 3 3 3 1 GWT1 SNF2_N PF00176.23 CEP14510.1 - 9.5e-65 218.6 3.6 3e-64 216.9 3.6 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CEP14510.1 - 4e-23 81.1 3.8 3e-13 49.4 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CEP14510.1 - 1.3e-19 70.5 0.0 8.1e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 CEP14510.1 - 1.9e-18 66.6 0.0 1.9e-18 66.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Cdh1_DBD_1 PF18196.1 CEP14510.1 - 5e-08 33.3 0.2 5e-08 33.3 0.2 7.2 5 1 0 6 6 6 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 CEP14510.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CEP14510.1 - 0.014 15.5 0.7 0.061 13.5 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF4078 PF13300.6 CEP14511.1 - 2.1e-23 82.4 13.0 2.1e-23 82.4 13.0 3.5 3 2 0 3 3 3 1 Domain of unknown function (DUF4078) CITED PF04487.12 CEP14511.1 - 0.17 12.0 3.0 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 CITED RT_RNaseH_2 PF17919.1 CEP14516.1 - 1.8e-24 85.7 0.0 4.9e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP14516.1 - 1.6e-17 63.7 0.0 4.6e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP14516.1 - 9.7e-17 61.2 5.1 1.3e-16 60.8 1.6 2.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP14516.1 - 3.8e-15 56.1 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP14516.1 - 3.1e-12 46.4 2.1 3.1e-12 46.4 2.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CEP14516.1 - 1.6e-09 37.5 0.2 4e-09 36.2 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP14516.1 - 2.3e-05 24.5 1.8 5.6e-05 23.3 1.8 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 CEP14516.1 - 0.00012 22.6 0.1 0.00043 20.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP14516.1 - 0.00039 21.0 0.0 0.00096 19.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease KAsynt_C_assoc PF16197.5 CEP14516.1 - 2.4 8.6 5.3 45 4.5 0.3 3.2 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension DUF4407 PF14362.6 CEP14518.1 - 0.0015 18.0 3.8 0.002 17.5 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 CEP14518.1 - 0.0058 16.9 3.6 0.0058 16.9 3.6 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 Jnk-SapK_ap_N PF09744.9 CEP14518.1 - 0.041 14.1 5.5 0.057 13.6 5.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mannitol_dh PF01232.23 CEP14518.1 - 0.15 12.2 1.6 0.49 10.5 0.4 1.8 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain JIP_LZII PF16471.5 CEP14518.1 - 0.18 12.0 7.6 0.55 10.4 7.6 1.8 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II Muted PF14942.6 CEP14518.1 - 0.26 11.6 6.6 0.29 11.5 5.7 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Csm1_N PF18504.1 CEP14518.1 - 0.29 11.5 8.5 0.66 10.4 6.0 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 CEP14518.1 - 0.65 10.3 6.8 0.7 10.2 1.8 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain zf-CCHC PF00098.23 CEP14519.1 - 0.00065 19.7 2.8 0.0014 18.6 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle CytoC_RC PF02276.18 CEP14519.1 - 0.017 14.5 0.5 0.027 13.8 0.5 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Sir1 PF11603.8 CEP14520.1 - 0.01 16.3 0.3 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Regulatory protein Sir1 TH1 PF04858.13 CEP14521.1 - 8.5e-88 295.4 3.4 1.1e-87 295.0 3.4 1.0 1 0 0 1 1 1 1 TH1 protein Chromo PF00385.24 CEP14522.1 - 4.2e-07 29.8 1.7 7.9e-07 28.9 1.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP14522.1 - 0.18 11.7 1.2 0.2 11.6 0.3 1.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain HTH_23 PF13384.6 CEP14523.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 CEP14523.1 - 0.041 14.1 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 CEP14524.1 - 1.7e-22 79.7 0.0 2.6e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease MFS_1 PF07690.16 CEP14526.1 - 6.8e-47 160.1 26.6 6.8e-47 160.1 26.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CEP14526.1 - 1.4e-07 30.2 0.1 3.8e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 CEP14526.1 - 0.0028 17.0 6.5 0.0028 17.0 6.5 3.0 2 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB URO-D PF01208.17 CEP14527.1 - 1.3e-129 432.3 0.0 1.5e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Glyco_hydro_3_C PF01915.22 CEP14528.1 - 1.1e-60 205.1 0.0 2e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CEP14528.1 - 1.3e-42 146.3 0.1 2e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CEP14528.1 - 9.4e-21 73.7 0.1 1.7e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain C9orf72-like PF15019.6 CEP14529.1 - 1.5e-27 96.7 0.3 4.7e-21 75.4 0.0 2.3 1 1 1 2 2 2 2 C9orf72-like protein family 4HBT_3 PF13622.6 CEP14529.1 - 0.086 13.1 1.4 0.18 12.1 1.4 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily 6PF2K PF01591.18 CEP14530.1 - 7e-61 205.4 0.4 7e-61 205.4 0.4 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP14530.1 - 3.7e-31 108.3 0.1 1.9e-23 83.2 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF5128 PF17170.4 CEP14530.1 - 0.0086 15.3 0.3 0.019 14.1 0.3 1.5 1 0 0 1 1 1 1 6-bladed beta-propeller CtaG_Cox11 PF04442.14 CEP14531.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF1863 PF08937.11 CEP14531.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) NFACT-R_1 PF05670.13 CEP14532.1 - 5.5e-33 113.9 0.7 1.9e-32 112.1 0.0 2.4 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CEP14532.1 - 7e-31 106.3 0.1 7e-31 106.3 0.1 5.1 3 1 2 5 5 5 1 NFACT protein C-terminal domain AF-4 PF05110.13 CEP14532.1 - 6.7e-06 24.5 31.1 6.7e-06 24.5 31.1 2.1 2 1 0 2 2 2 1 AF-4 proto-oncoprotein NFACT-R_2 PF18297.1 CEP14532.1 - 0.0041 17.3 0.1 3 8.1 0.0 3.9 3 1 0 3 3 3 1 NFACT protein RNA binding domain eIF-3c_N PF05470.12 CEP14533.1 - 1.2e-176 588.6 27.1 2e-143 478.9 0.8 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CEP14533.1 - 9e-15 55.1 0.1 2.8e-14 53.5 0.1 1.9 1 0 0 1 1 1 1 PCI domain HemX PF04375.14 CEP14533.1 - 1.1 8.5 10.5 0.18 11.1 4.7 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase EMP24_GP25L PF01105.24 CEP14534.1 - 3.4e-49 167.2 1.0 4e-49 167.0 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD End3 PF12761.7 CEP14534.1 - 0.0064 16.7 0.9 0.0082 16.3 0.9 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Big_8 PF17961.1 CEP14534.1 - 0.07 13.3 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Bacterial Ig domain F-box-like PF12937.7 CEP14535.1 - 6.6e-07 29.1 0.1 1.6e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 CEP14536.1 - 9.5e-08 31.8 1.3 2.4e-07 30.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP14536.1 - 2.9e-05 23.8 0.1 7.4e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain Homez PF11569.8 CEP14536.1 - 0.00041 19.8 0.1 0.0013 18.1 0.1 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Pex16 PF08610.10 CEP14537.1 - 0.0036 16.5 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Thiolase_N PF00108.23 CEP14538.1 - 4.8e-79 265.4 4.4 8.4e-79 264.6 3.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP14538.1 - 1.1e-46 157.4 0.1 2.1e-46 156.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain HisKA_2 PF07568.12 CEP14539.1 - 0.029 14.4 0.0 0.89 9.7 0.0 2.6 3 0 0 3 3 3 0 Histidine kinase Mo25 PF08569.11 CEP14540.1 - 5.6e-131 436.8 19.2 6.8e-131 436.5 19.2 1.1 1 0 0 1 1 1 1 Mo25-like Lipocalin_7 PF14651.6 CEP14540.1 - 0.072 13.0 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family GYF PF02213.16 CEP14541.1 - 2.3e-18 65.6 1.9 3.4e-18 65.0 0.6 2.0 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 CEP14541.1 - 0.0008 19.2 0.3 0.0029 17.4 0.1 2.1 2 0 0 2 2 2 1 GYF domain 2 PMEI PF04043.15 CEP14542.1 - 0.074 13.4 0.4 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor RVT_1 PF00078.27 CEP14543.1 - 2.6e-13 50.0 0.6 1.1e-09 38.2 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4939 PF16297.5 CEP14544.1 - 1.3e-05 25.1 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Erp_C PF06780.11 CEP14544.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Erp protein C-terminus RVT_1 PF00078.27 CEP14545.1 - 4.4e-16 59.1 0.1 1.3e-15 57.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 CEP14545.1 - 2.8e-05 24.0 0.1 0.00012 22.0 0.1 2.1 1 0 0 1 1 1 1 Phage integrase family YihI PF04220.12 CEP14545.1 - 0.098 12.4 0.9 7.1 6.3 0.8 2.9 3 0 0 3 3 3 0 Der GTPase activator (YihI) Mucin PF01456.17 CEP14545.1 - 6.7 6.7 9.0 33 4.5 3.5 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein PIF1 PF05970.14 CEP14546.1 - 1e-41 143.3 0.0 1.2e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Fe-S_biosyn PF01521.20 CEP14548.1 - 2.5e-20 72.7 0.0 3.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SET PF00856.28 CEP14549.1 - 7.4e-18 65.5 0.0 7.4e-18 65.5 0.0 4.2 4 2 0 4 4 4 1 SET domain AWS PF17907.1 CEP14549.1 - 1.9e-11 43.8 9.2 1.9e-11 43.8 9.2 2.3 2 0 0 2 2 2 1 AWS domain WW PF00397.26 CEP14549.1 - 2.5e-08 33.9 1.6 7.4e-08 32.4 1.6 1.9 1 0 0 1 1 1 1 WW domain SRI PF08236.11 CEP14549.1 - 3.8e-07 30.2 3.4 3.8e-07 30.2 3.4 2.3 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain DUF2704 PF10866.8 CEP14549.1 - 0.056 13.3 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Glyco_hydro_47 PF01532.20 CEP14550.1 - 9.1e-124 413.8 0.1 1.3e-123 413.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 CEP14550.1 - 2.3e-10 40.4 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 PA domain LNS2 PF08235.13 CEP14551.1 - 1.2e-103 345.5 0.1 3.8e-103 343.8 0.0 1.8 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CEP14551.1 - 6.2e-42 141.7 0.1 1.1e-41 140.9 0.1 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CEP14551.1 - 9.5e-20 70.6 0.0 2.8e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain TFIIA PF03153.13 CEP14553.1 - 9.1 6.2 15.4 10 6.0 15.4 1.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-1a PF01176.19 CEP14554.1 - 1.4e-14 53.6 0.1 1.9e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Oxidored_FMN PF00724.20 CEP14555.1 - 2e-105 352.8 0.0 2.4e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DHHC PF01529.20 CEP14556.1 - 3.6e-08 33.6 7.8 5.4e-08 33.0 7.8 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase FYVE PF01363.21 CEP14556.1 - 1.6 9.0 11.5 3.4 7.9 11.5 1.5 1 1 0 1 1 1 0 FYVE zinc finger RhoGEF PF00621.20 CEP14557.1 - 1.1e-36 126.8 6.0 1.1e-36 126.8 6.0 2.9 4 0 0 4 4 4 1 RhoGEF domain eIF-5a PF01287.20 CEP14557.1 - 1.2e-27 95.8 0.7 1.2e-27 95.8 0.7 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SH3_2 PF07653.17 CEP14557.1 - 0.00026 20.6 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TruB_N PF01509.18 CEP14557.1 - 0.13 12.6 1.2 20 5.6 0.1 3.4 2 1 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) CtaG_Cox11 PF04442.14 CEP14558.1 - 8.6e-61 204.4 0.1 1.1e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RhoGAP PF00620.27 CEP14559.1 - 4.1e-38 130.6 1.4 4.1e-38 130.6 1.4 2.1 3 0 0 3 3 3 1 RhoGAP domain SOG2 PF10428.9 CEP14560.1 - 0.23 10.6 7.3 0.27 10.4 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PARM PF17061.5 CEP14560.1 - 0.58 10.2 9.4 0.78 9.8 9.4 1.1 1 0 0 1 1 1 0 PARM DUF4837 PF16125.5 CEP14562.1 - 0.076 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) PDEase_II PF02112.15 CEP14563.1 - 0.083 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II NDC10_II PF16787.5 CEP14564.1 - 0.00074 18.7 0.1 0.00098 18.3 0.1 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Urb2 PF10441.9 CEP14564.1 - 0.034 14.1 0.1 0.046 13.7 0.1 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family Pec_lyase PF09492.10 CEP14564.1 - 0.064 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Pectic acid lyase DUF1841 PF08897.11 CEP14565.1 - 0.059 13.4 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Integrase_H2C2 PF17921.1 CEP14566.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP14566.1 - 2.8e-06 27.5 0.5 5.4e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 H2C2 zinc finger Integrase_Zn PF02022.19 CEP14566.1 - 0.0032 17.4 1.1 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 Integrase Zinc binding domain rve PF00665.26 CEP14566.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DNA_pol_A_exo1 PF01612.20 CEP14567.1 - 0.00015 21.5 0.0 0.0006 19.6 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease XET_C PF06955.12 CEP14567.1 - 0.062 13.2 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus DUF1041 PF06292.17 CEP14568.1 - 0.011 16.2 0.0 0.013 15.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) RT_RNaseH PF17917.1 CEP14569.1 - 8.6e-21 74.2 0.4 3.1e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP14569.1 - 1.7e-16 60.1 0.6 4.4e-16 58.7 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP14569.1 - 2.4e-14 53.5 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CEP14569.1 - 3.1e-11 43.2 0.1 2.1e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 CEP14569.1 - 0.059 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 CEP14571.1 - 1.6e-07 31.1 0.3 2.9e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MLVIN_C PF18697.1 CEP14571.1 - 0.053 13.6 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF3712 PF12505.8 CEP14575.1 - 2.4e-68 228.2 35.9 1.8e-23 83.1 0.3 8.1 7 1 1 8 8 8 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CEP14575.1 - 2.4e-11 44.1 11.0 0.0021 18.5 0.0 7.4 7 0 0 7 7 7 3 Late embryogenesis abundant protein RIFIN PF02009.16 CEP14575.1 - 0.043 13.7 6.1 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Rifin Baculo_11_kDa PF06143.11 CEP14575.1 - 1.2 8.7 3.3 3.2 7.4 3.3 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF1356 PF07092.12 CEP14575.1 - 4.2 6.6 6.6 11 5.2 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1356) ICAM_N PF03921.14 CEP14576.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF2407 PF10302.9 CEP14576.1 - 0.16 12.5 0.8 0.28 11.8 0.1 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain PQ-loop PF04193.14 CEP14578.1 - 7e-16 57.8 1.8 7e-16 57.8 1.8 2.9 3 1 1 4 4 4 1 PQ loop repeat ER_lumen_recept PF00810.18 CEP14578.1 - 0.0012 19.7 4.0 0.0012 19.7 4.0 2.1 2 1 0 2 2 2 1 ER lumen protein retaining receptor 2-oxoacid_dh PF00198.23 CEP14579.1 - 8.3e-82 274.1 0.0 1.1e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEP14579.1 - 7.7e-18 64.1 0.5 1.8e-17 62.9 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEP14579.1 - 7.6e-13 48.6 0.6 2e-12 47.2 0.6 1.8 1 0 0 1 1 1 1 e3 binding domain Ribosomal_60s PF00428.19 CEP14579.1 - 4.1 8.0 14.0 1.4 9.6 8.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein GATA PF00320.27 CEP14580.1 - 7.4e-31 105.5 20.6 2.1e-15 56.0 5.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP14580.1 - 3.5e-06 26.4 7.3 0.0082 15.6 1.0 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CEP14580.1 - 0.00022 21.3 1.4 0.55 10.4 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 CEP14580.1 - 0.00052 20.1 8.0 0.17 12.0 0.5 2.9 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CEP14580.1 - 0.78 9.6 6.3 2.7 7.9 0.7 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 CEP14580.1 - 1.1 9.2 12.7 0.9 9.5 0.8 3.1 2 1 1 3 3 3 0 Putative transposase DNA-binding domain IMPa_helical PF18642.1 CEP14581.1 - 0.14 12.6 1.0 2.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain PBP PF01161.20 CEP14582.1 - 1.8e-12 47.7 0.3 2.1e-11 44.2 0.3 2.1 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.22 CEP14583.1 - 6.1e-59 198.2 0.3 7.3e-59 198.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP14583.1 - 8.1e-36 122.9 0.1 2.9e-35 121.1 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP14583.1 - 7.3e-15 54.9 0.0 9.1e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP14583.1 - 3.4e-07 29.8 0.0 4.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP14583.1 - 3.8e-06 26.6 0.1 5.1e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP14583.1 - 4.4e-06 26.8 0.0 8.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEP14583.1 - 4.5e-05 23.9 0.1 8e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEP14583.1 - 0.00062 19.7 0.4 0.39 10.6 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEP14583.1 - 0.035 14.4 0.1 0.26 11.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 CEP14583.1 - 0.064 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Zn_clus PF00172.18 CEP14584.1 - 1.1e-08 35.0 8.1 1.9e-08 34.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDHD PF02862.17 CEP14585.1 - 2.9e-19 70.1 1.1 4.5e-19 69.5 1.1 1.4 1 0 0 1 1 1 1 DDHD domain SUIM_assoc PF16619.5 CEP14585.1 - 0.00016 21.6 3.0 0.00045 20.2 3.0 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CEP14585.1 - 0.017 14.8 7.1 0.025 14.2 7.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF4770 PF15994.5 CEP14585.1 - 0.13 12.5 5.8 0.25 11.6 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Androgen_recep PF02166.16 CEP14585.1 - 0.49 9.2 5.7 0.69 8.7 5.7 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2722 PF10846.8 CEP14585.1 - 0.72 8.7 12.9 1.2 8.0 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FBPase PF00316.20 CEP14586.1 - 2.7e-73 245.5 0.1 3.6e-73 245.1 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 CEP14586.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M HLH PF00010.26 CEP14587.1 - 7.6e-13 48.2 0.5 7.6e-13 48.2 0.5 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HSL_N PF06350.12 CEP14587.1 - 0.073 12.0 1.3 0.13 11.2 1.3 1.4 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus LMBR1 PF04791.16 CEP14587.1 - 4.3 6.1 5.3 5.4 5.8 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein VTC PF09359.10 CEP14588.1 - 8.1e-84 281.3 0.1 1.5e-83 280.3 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CEP14588.1 - 1.1e-12 48.6 14.0 2.1e-06 27.9 0.2 4.2 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.15 CEP14588.1 - 2.9e-12 46.8 3.3 6.2e-12 45.8 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) JAB PF01398.21 CEP14589.1 - 4.5e-33 113.7 0.0 9.7e-33 112.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CEP14589.1 - 4.9e-14 52.7 1.6 6.4e-14 52.3 0.8 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CEP14589.1 - 2e-06 27.6 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 CEP14589.1 - 0.068 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) MbeB_N PF04837.12 CEP14589.1 - 0.16 12.3 1.3 0.35 11.2 1.3 1.5 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Mito_carr PF00153.27 CEP14590.1 - 3.1e-46 155.2 6.7 9.7e-15 54.3 0.8 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med6 PF04934.14 CEP14591.1 - 1.2e-23 83.3 0.0 2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Pho88 PF10032.9 CEP14592.1 - 1.1e-34 119.3 1.1 3.2e-29 101.5 0.2 2.0 1 1 1 2 2 2 2 Phosphate transport (Pho88) GntP_permease PF02447.16 CEP14592.1 - 0.12 11.0 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 GntP family permease DUF3784 PF12650.7 CEP14592.1 - 0.17 12.1 2.3 1.9 8.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) RT_RNaseH_2 PF17919.1 CEP14593.1 - 1.1e-22 79.9 0.0 2.1e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP14593.1 - 5.8e-14 52.2 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP14593.1 - 1.2e-11 44.5 0.0 3.5e-11 43.1 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_7 PF02796.15 CEP14594.1 - 4.3e-08 33.1 2.6 1.6e-05 24.9 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 CEP14594.1 - 1.4e-06 28.2 0.0 0.00031 20.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 CEP14594.1 - 1.7e-06 28.2 1.2 2.5e-06 27.6 0.5 1.7 2 0 0 2 2 2 1 Transposase TrmB PF01978.19 CEP14594.1 - 0.00011 22.0 0.1 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_32 PF13565.6 CEP14594.1 - 0.00052 20.6 0.4 0.00083 19.9 0.4 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 CEP14594.1 - 0.00077 19.2 0.2 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP14594.1 - 0.0091 15.8 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.18 CEP14594.1 - 0.0093 15.9 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_24 PF13412.6 CEP14594.1 - 0.01 15.4 0.0 0.69 9.5 0.0 2.7 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 CEP14594.1 - 0.019 15.1 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TnsD PF15978.5 CEP14594.1 - 0.024 13.6 0.1 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_Tnp_Tc3_1 PF11427.8 CEP14594.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Tc3 transposase HTH_11 PF08279.12 CEP14594.1 - 0.076 13.0 0.9 3.3 7.7 0.0 2.6 3 0 0 3 3 3 0 HTH domain HLH PF00010.26 CEP14595.1 - 2.4e-18 65.8 2.4 8.2e-18 64.1 0.1 3.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain FUSC PF04632.12 CEP14595.1 - 3.3 6.1 8.3 4.4 5.7 1.4 2.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family ARD PF03079.14 CEP14595.1 - 4.8 7.3 6.4 20 5.4 6.4 2.0 1 0 0 1 1 1 0 ARD/ARD' family PDDEXK_6 PF04720.12 CEP14596.1 - 0.58 10.1 3.7 1.1 9.2 0.1 2.4 3 0 0 3 3 3 0 PDDEXK-like family of unknown function VPS9 PF02204.18 CEP14599.1 - 7e-24 84.0 0.2 1.7e-23 82.8 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Utp14 PF04615.13 CEP14600.1 - 2.1 6.8 36.2 2.5 6.6 36.2 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.7 CEP14600.1 - 4 5.4 36.4 4.8 5.2 36.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.12 CEP14600.1 - 8.2 5.7 54.8 13 5.1 54.8 1.3 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 CEP14601.1 - 0.49 8.9 38.0 0.57 8.7 38.0 1.1 1 0 0 1 1 1 0 Utp14 protein DPBB_1 PF03330.18 CEP14602.1 - 7.1e-08 32.6 0.0 1.6e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Peptidase_S28 PF05577.12 CEP14603.1 - 3.4e-71 240.3 0.0 5.2e-71 239.7 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 AvrPto PF11592.8 CEP14603.1 - 0.053 13.5 0.1 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto Ribosomal_S19 PF00203.21 CEP14604.1 - 2.1e-33 114.0 0.6 2.8e-33 113.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 CEP14604.1 - 0.16 12.0 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH DDE_3 PF13358.6 CEP14605.1 - 8.6e-14 51.5 0.0 4e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease zf-MIZ PF02891.20 CEP14605.1 - 0.11 12.3 3.9 0.22 11.3 0.7 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger SRP14 PF02290.15 CEP14606.1 - 4.9e-22 78.1 0.3 1.8e-19 69.9 0.2 2.7 2 0 0 2 2 2 2 Signal recognition particle 14kD protein DDE_3 PF13358.6 CEP14606.1 - 4.4e-09 36.3 0.0 1.1e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease NAD_binding_10 PF13460.6 CEP14607.1 - 0.01 15.8 0.0 0.052 13.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Cyclin_N PF00134.23 CEP14608.1 - 3e-09 36.7 1.4 3.5e-09 36.5 0.5 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CEP14608.1 - 3.2e-05 23.9 3.4 0.00047 20.2 0.1 2.6 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 CEP14608.1 - 0.00073 19.6 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain CBFD_NFYB_HMF PF00808.23 CEP14609.1 - 3.3e-15 56.1 0.4 5.3e-15 55.5 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP14609.1 - 2.2e-11 44.2 0.1 2.2e-11 44.2 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Na_K-ATPase PF00287.18 CEP14609.1 - 1.8 7.7 9.0 2.3 7.3 8.5 1.4 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain DEAD PF00270.29 CEP14610.1 - 1.8e-45 154.8 0.5 3.5e-45 153.9 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP14610.1 - 7.6e-32 110.0 0.3 8e-31 106.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Methyltransf_23 PF13489.6 CEP14610.1 - 9.8e-19 67.8 0.1 1.8e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP14610.1 - 5.2e-07 30.3 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP14610.1 - 2.3e-05 25.0 0.0 6.9e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain AAA_19 PF13245.6 CEP14610.1 - 0.00012 22.4 0.2 0.0018 18.7 0.1 2.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 CEP14610.1 - 0.00038 20.5 0.0 0.00088 19.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.6 CEP14610.1 - 0.0004 20.2 0.0 0.0017 18.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain AAA_30 PF13604.6 CEP14610.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ORC4_C PF14629.6 CEP14610.1 - 0.071 12.5 1.6 0.12 11.8 0.2 1.9 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Helicase_RecD PF05127.14 CEP14610.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase Methyltransf_11 PF08241.12 CEP14611.1 - 5.3e-20 71.9 0.0 7.9e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP14611.1 - 4e-19 69.1 0.0 6.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP14611.1 - 2.6e-16 59.8 0.0 3.2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP14611.1 - 1.6e-15 57.4 0.0 2.6e-15 56.7 0.0 1.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CEP14611.1 - 4.8e-13 48.7 0.0 7.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CEP14611.1 - 4.2e-10 40.3 0.0 6.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP14611.1 - 3.9e-08 33.0 0.0 5.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CEP14611.1 - 2e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CEP14611.1 - 5.6e-05 22.6 0.0 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CEP14611.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CEP14611.1 - 0.00052 19.6 0.0 0.00073 19.2 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 CEP14611.1 - 0.001 18.5 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 CEP14611.1 - 0.0047 15.5 0.0 0.0065 15.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 CEP14611.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 CEP14611.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 CEP14611.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 CEP14611.1 - 0.048 13.6 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FtsJ PF01728.19 CEP14611.1 - 0.049 13.7 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 CEP14611.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase WW PF00397.26 CEP14612.1 - 6.9e-07 29.3 1.1 1.5e-06 28.2 1.1 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 CEP14612.1 - 0.014 15.5 22.9 0.014 15.5 22.9 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Spore-coat_CotD PF11122.8 CEP14612.1 - 0.028 15.2 4.0 0.073 13.9 4.0 1.7 1 0 0 1 1 1 0 Inner spore coat protein D ARS2 PF04959.13 CEP14612.1 - 0.085 13.2 10.2 0.17 12.2 10.2 1.5 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DGF-1_C PF11040.8 CEP14612.1 - 0.18 11.8 1.2 0.35 10.9 1.2 1.5 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TFIIA PF03153.13 CEP14612.1 - 0.55 10.2 14.7 0.66 9.9 14.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3684 PF12449.8 CEP14613.1 - 4.4e-285 948.7 10.5 1.5e-279 930.4 4.5 2.3 2 1 0 3 3 3 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 CEP14613.1 - 0.0004 20.2 0.0 0.00095 19.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2076 PF09849.9 CEP14613.1 - 0.12 12.4 1.0 0.26 11.3 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) WLM PF08325.10 CEP14613.1 - 0.15 12.1 0.4 0.42 10.7 0.4 1.7 1 0 0 1 1 1 0 WLM domain SPACA7 PF15307.6 CEP14613.1 - 0.16 12.3 0.5 0.8 10.0 0.0 2.5 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 COX6A PF02046.15 CEP14614.1 - 1.5e-30 105.9 1.5 1.8e-30 105.7 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PAP_PilO PF06864.12 CEP14614.1 - 0.012 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) zf-MYND PF01753.18 CEP14616.1 - 6.5e-06 26.1 9.8 6.5e-06 26.1 9.8 2.7 3 0 0 3 3 3 1 MYND finger TPR_1 PF00515.28 CEP14616.1 - 0.057 13.3 0.0 1.7 8.6 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 CEP14616.1 - 0.13 11.8 1.9 0.19 11.3 1.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pet127 PF08634.10 CEP14617.1 - 2.8e-107 358.2 3.8 2.8e-107 358.2 3.8 2.1 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Peptidase_M57 PF12388.8 CEP14617.1 - 0.0075 15.9 0.7 1.7 8.2 0.1 2.3 2 0 0 2 2 2 2 Dual-action HEIGH metallo-peptidase Tyr_Deacylase PF02580.16 CEP14617.1 - 0.17 12.4 0.1 0.38 11.3 0.1 1.5 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase Ribosomal_L31 PF01197.18 CEP14618.1 - 1.6e-06 28.2 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Phage_capsid PF05065.13 CEP14618.1 - 0.042 13.1 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Phage capsid family AMP-binding_C_2 PF14535.6 CEP14619.1 - 0.072 13.4 0.6 0.096 13.0 0.6 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF4144 PF13642.6 CEP14620.1 - 0.029 15.0 0.1 0.065 13.8 0.1 1.5 1 0 0 1 1 1 0 protein structure with unknown function RT_RNaseH_2 PF17919.1 CEP14621.1 - 2.3e-34 117.4 0.0 5.9e-34 116.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP14621.1 - 3.6e-33 114.0 0.0 1.5e-32 112.0 0.0 2.2 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP14621.1 - 3.3e-19 68.7 0.4 7.7e-19 67.6 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP14621.1 - 5.4e-17 62.1 0.0 1.3e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP14621.1 - 4.9e-16 58.9 0.0 1.2e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 CEP14621.1 - 2.1e-05 24.7 0.5 2.1e-05 24.7 0.5 2.4 3 0 0 3 3 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CEP14621.1 - 5.5e-05 23.7 0.0 0.00031 21.3 0.0 2.3 2 1 1 3 3 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP14621.1 - 0.00088 19.8 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Dimerisation PF08100.11 CEP14621.1 - 0.015 15.3 0.1 0.065 13.3 0.0 2.1 2 0 0 2 2 1 0 Dimerisation domain zf-H2C2 PF09337.10 CEP14621.1 - 0.038 14.2 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 CEP14621.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVP_2 PF08284.11 CEP14621.1 - 0.096 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 CEP14621.1 - 0.13 12.0 1.9 0.38 10.4 0.2 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type CLZ PF16526.5 CEP14621.1 - 0.9 9.9 2.6 3.7 8.0 2.6 2.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HTH_Tnp_Tc3_2 PF01498.18 CEP14622.1 - 1.4e-11 44.5 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Transposase Hamartin PF04388.12 CEP14624.1 - 8.6 4.9 6.1 12 4.4 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein NUP214 PF16755.5 CEP14626.1 - 1.8e-10 40.6 0.3 2.9e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 CEP14626.1 - 0.0012 19.1 0.1 0.03 14.6 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CEP14626.1 - 0.035 13.5 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF5471 PF17565.2 CEP14626.1 - 9.1 6.6 9.4 40 4.6 5.9 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5471) p53-inducible11 PF14936.6 CEP14627.1 - 0.11 12.5 0.4 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF3681 PF12442.8 CEP14627.1 - 1.4 9.4 6.0 3.5 8.2 1.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) Ribosomal_L26 PF16906.5 CEP14628.1 - 2e-36 124.3 4.4 2.5e-36 124.0 4.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CEP14628.1 - 2.3e-10 40.1 2.9 2.3e-10 40.1 2.9 1.7 2 0 0 2 2 2 1 KOW motif DUF1442 PF07279.11 CEP14628.1 - 0.0084 15.4 1.4 0.01 15.2 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) DUF5634 PF18681.1 CEP14628.1 - 0.14 12.6 0.0 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5634) zf-RING_2 PF13639.6 CEP14629.1 - 3e-12 46.6 7.0 4.9e-12 46.0 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP14629.1 - 8.7e-10 38.2 4.3 1.9e-09 37.1 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEP14629.1 - 1.3e-07 31.3 7.5 2.2e-07 30.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP14629.1 - 1.5e-07 31.6 3.2 3.2e-07 30.5 3.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CEP14629.1 - 1.3e-06 28.2 6.1 2.2e-06 27.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CEP14629.1 - 0.00033 20.6 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 CEP14629.1 - 0.0011 18.9 2.5 0.0011 18.9 2.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP14629.1 - 0.0076 16.1 8.2 0.014 15.2 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP14629.1 - 0.015 15.2 5.8 0.024 14.6 5.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP14629.1 - 0.023 14.8 1.7 0.052 13.6 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UL42 PF17638.2 CEP14629.1 - 0.075 13.0 0.2 0.075 13.0 0.2 2.1 2 0 0 2 2 2 0 HCMV UL42 DUF4381 PF14316.6 CEP14629.1 - 0.12 12.6 0.2 0.12 12.6 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) Prok-RING_4 PF14447.6 CEP14629.1 - 0.25 11.3 9.9 0.42 10.5 9.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Acatn PF13000.7 CEP14630.1 - 9.8e-174 578.9 25.2 1.3e-89 301.3 15.6 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 F-box-like PF12937.7 CEP14631.1 - 3.1e-05 23.8 0.0 7.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like PPR_2 PF13041.6 CEP14632.1 - 2.4e-11 43.7 0.9 2.8e-07 30.6 0.0 4.2 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 CEP14632.1 - 8.1e-07 28.9 0.0 4.7 7.7 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 CEP14632.1 - 0.00065 19.7 2.0 0.016 15.3 0.1 2.5 1 1 1 2 2 2 2 Pentatricopeptide repeat domain DUF1400 PF07176.11 CEP14632.1 - 0.0056 17.0 0.8 1.3 9.3 0.0 2.9 3 1 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF1400) TPR_19 PF14559.6 CEP14632.1 - 0.042 14.4 0.0 5.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.7 CEP14632.1 - 0.082 12.6 7.9 26 4.6 0.1 4.3 4 0 0 4 4 4 0 PPR repeat MKT1_C PF12246.8 CEP14633.1 - 8.9e-68 228.1 2.2 1.3e-67 227.6 2.2 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CEP14633.1 - 3.5e-34 117.0 0.2 1.2e-33 115.3 0.2 2.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CEP14633.1 - 1.8e-07 31.6 0.0 5.6e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain CBS PF00571.28 CEP14634.1 - 6.5e-08 32.9 0.4 0.035 14.6 0.1 4.2 4 0 0 4 4 4 2 CBS domain tRNA_SAD PF07973.14 CEP14634.1 - 4.9e-07 29.8 0.1 1.4e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CEP14634.1 - 0.00033 19.3 0.2 0.0007 18.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 CEP14634.1 - 0.00056 20.3 0.7 0.0013 19.1 0.7 1.8 1 0 0 1 1 1 1 DHHA1 domain ApoLp-III PF07464.11 CEP14634.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PocR PF10114.9 CEP14634.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR XRCC4 PF06632.12 CEP14635.1 - 2.9e-07 29.7 8.7 3.7e-07 29.3 8.7 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 BUD22 PF09073.10 CEP14635.1 - 0.0062 15.9 12.7 0.0082 15.5 12.7 1.1 1 0 0 1 1 1 1 BUD22 Adeno_PV PF03910.13 CEP14635.1 - 0.0068 15.2 4.4 0.012 14.4 4.4 1.3 1 0 0 1 1 1 1 Adenovirus minor core protein PV DUF3246 PF11596.8 CEP14635.1 - 0.011 15.1 6.2 0.017 14.6 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Dicty_REP PF05086.12 CEP14635.1 - 0.023 12.7 12.0 0.032 12.2 12.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FapA PF03961.13 CEP14635.1 - 0.082 11.5 7.6 0.12 10.9 7.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A 12TM_1 PF09847.9 CEP14635.1 - 0.2 10.7 0.2 0.27 10.3 0.2 1.1 1 0 0 1 1 1 0 Membrane protein of 12 TMs DDHD PF02862.17 CEP14635.1 - 0.86 9.7 5.3 1.2 9.3 5.3 1.2 1 0 0 1 1 1 0 DDHD domain Snapin_Pallidin PF14712.6 CEP14635.1 - 4.9 7.6 12.0 0.77 10.2 7.4 1.9 2 0 0 2 2 2 0 Snapin/Pallidin ALMT PF11744.8 CEP14635.1 - 5.6 5.7 10.3 7.4 5.3 10.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FlxA PF14282.6 CEP14635.1 - 5.8 7.0 17.7 1.8e+02 2.2 17.5 2.4 1 1 0 1 1 1 0 FlxA-like protein SOGA PF11365.8 CEP14635.1 - 6.5 8.0 13.0 3.8 8.7 6.8 2.4 2 0 0 2 2 2 0 Protein SOGA Nrap_D5 PF17406.2 CEP14637.1 - 1.3e-54 184.4 2.0 1.2e-52 177.9 1.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CEP14637.1 - 1.8e-50 171.3 0.2 3.5e-50 170.3 0.1 1.6 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CEP14637.1 - 3e-46 157.4 0.0 5.5e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CEP14637.1 - 1.3e-45 154.9 0.2 6.8e-43 146.0 0.2 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CEP14637.1 - 3.7e-44 150.4 0.0 1.1e-43 148.9 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 CEP14637.1 - 3.2e-27 95.4 0.0 1.7e-26 93.1 0.0 2.3 1 0 0 1 1 1 1 Nrap protein domain 6 Med5 PF08689.10 CEP14637.1 - 0.002 16.0 0.1 0.003 15.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Nop PF01798.18 CEP14638.1 - 2.4e-86 289.0 0.3 2.4e-86 289.0 0.3 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CEP14638.1 - 1.3e-21 76.7 1.1 1.3e-21 76.7 1.1 2.8 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RVT_1 PF00078.27 CEP14639.1 - 3.5e-15 56.1 0.0 5.8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Isochorismatase PF00857.20 CEP14642.1 - 0.00058 20.1 0.0 0.00085 19.5 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CEP14646.1 - 5.3e-08 33.2 0.0 8.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RSN1_7TM PF02714.15 CEP14647.1 - 2.1e-57 194.5 26.1 2.1e-57 194.5 26.1 2.3 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP14647.1 - 3.7e-31 108.7 0.1 5.5e-30 104.9 0.0 2.7 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEP14647.1 - 2.7e-29 101.9 1.8 1.2e-28 99.8 1.5 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4762 PF15959.5 CEP14647.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) PSI_8 PF00796.18 CEP14647.1 - 4.1 7.3 9.2 0.2 11.5 2.3 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Rho_GDI PF02115.17 CEP14650.1 - 0.0091 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Wbp11 PF09429.10 CEP14653.1 - 6e-22 77.8 13.7 6e-22 77.8 13.7 2.3 2 1 0 2 2 2 1 WW domain binding protein 11 SAPS PF04499.15 CEP14653.1 - 1.1 8.0 9.9 1.6 7.4 9.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRIQK PF15168.6 CEP14653.1 - 8.3 6.4 8.6 3.4 7.6 4.6 2.2 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family CBM_21 PF03370.13 CEP14654.1 - 8.7e-30 103.2 1.7 2e-29 102.0 1.7 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEP14654.1 - 1.2e-09 38.6 2.8 1.2e-09 38.6 2.8 1.9 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Homeobox_KN PF05920.11 CEP14656.1 - 2.6e-19 68.8 0.3 6.8e-19 67.5 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEP14656.1 - 1e-05 25.3 0.1 2.7e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain ANAPC1 PF12859.7 CEP14656.1 - 0.018 15.6 6.0 0.14 12.7 6.0 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF2285 PF10074.9 CEP14656.1 - 0.17 12.6 0.1 0.4 11.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) FAM176 PF14851.6 CEP14656.1 - 1 9.0 10.4 2.3 7.8 1.9 2.5 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 CEP14656.1 - 1.4 9.4 14.7 1.1 9.7 3.7 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CEP14656.1 - 5.7 7.4 11.2 2.3 8.6 4.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 CEP14656.1 - 5.9 4.8 12.9 0.68 7.9 6.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen zf-C5HC2 PF02928.16 CEP14658.1 - 0.00026 21.3 0.8 0.28 11.6 0.1 2.2 2 0 0 2 2 2 2 C5HC2 zinc finger TPR_10 PF13374.6 CEP14659.1 - 0.00036 20.3 2.3 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP14659.1 - 0.00057 20.1 4.1 0.32 11.3 5.4 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP14659.1 - 0.0069 16.2 4.9 1.7 8.6 1.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP14659.1 - 0.046 14.6 3.5 4.7 8.3 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat T3SS_needle_E PF08988.10 CEP14659.1 - 0.092 12.9 0.8 0.092 12.9 0.8 3.1 3 2 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle ATP13 PF12921.7 CEP14659.1 - 0.13 12.1 0.8 0.35 10.7 0.3 1.9 1 1 1 2 2 2 0 Mitochondrial ATPase expression TPR_2 PF07719.17 CEP14659.1 - 0.21 11.8 6.0 17 5.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 CEP14659.1 - 0.46 11.2 6.0 0.52 11.0 0.9 2.2 2 0 0 2 2 2 0 Cytochrome b562 TPR_17 PF13431.6 CEP14659.1 - 0.83 10.2 6.8 13 6.4 1.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEP14659.1 - 2.7 7.7 8.1 2.6 7.8 2.4 2.4 2 0 0 2 2 2 0 TPR repeat Sel1 PF08238.12 CEP14661.1 - 1.1e-13 51.4 17.2 3.1e-05 24.5 1.7 6.2 7 0 0 7 7 7 4 Sel1 repeat VWA_CoxE PF05762.14 CEP14661.1 - 0.055 12.8 0.2 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein TPR_2 PF07719.17 CEP14661.1 - 1.7 9.0 12.2 59 4.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF16 PF01519.16 CEP14661.1 - 2.9 8.4 11.6 6.5 7.3 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 Aldo_ket_red PF00248.21 CEP14663.1 - 2.7e-75 253.3 0.0 3e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3834 PF12916.7 CEP14663.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) SRPRB PF09439.10 CEP14664.1 - 2.3e-41 141.2 0.0 2.9e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CEP14664.1 - 2.1e-17 63.1 0.2 3.7e-17 62.3 0.1 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP14664.1 - 0.016 14.6 0.2 0.051 12.9 0.2 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 CEP14664.1 - 0.049 13.4 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Podoplanin PF05808.11 CEP14665.1 - 0.016 15.4 0.9 0.016 15.4 0.9 2.0 3 0 0 3 3 3 0 Podoplanin Mid2 PF04478.12 CEP14665.1 - 0.058 13.2 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Abhydrolase_1 PF00561.20 CEP14667.1 - 2.9e-15 56.6 0.0 7.2e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP14667.1 - 2e-06 27.3 0.0 3.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP14667.1 - 0.00038 21.1 0.0 0.00066 20.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CEP14669.1 - 7.7e-63 212.2 0.1 9.7e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CEP14669.1 - 3.1e-07 30.1 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 CEP14669.1 - 4.7e-07 29.0 0.1 2.2e-06 26.8 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 CEP14669.1 - 1e-05 24.6 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 CEP14669.1 - 0.055 12.1 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RVT_1 PF00078.27 CEP14670.1 - 8.5e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CEP14670.1 - 0.0033 16.9 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain zf-met PF12874.7 CEP14671.1 - 5.7e-09 36.1 77.3 0.0099 16.2 0.7 10.5 10 0 0 10 10 10 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP14671.1 - 0.00053 20.2 87.9 0.076 13.3 2.1 10.5 10 0 0 10 10 10 7 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEP14671.1 - 0.0015 18.8 63.1 0.0054 17.1 1.7 7.1 4 4 1 6 6 6 3 C2H2 type zinc-finger (2 copies) Syncollin PF15138.6 CEP14671.1 - 0.12 12.6 9.3 0.51 10.5 0.4 3.6 3 1 0 3 3 3 0 Syncollin FOXP-CC PF16159.5 CEP14671.1 - 0.14 12.8 37.3 5.1 7.8 1.1 8.1 8 0 0 8 8 8 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CEP14671.1 - 0.87 10.6 98.8 1.5 9.8 2.7 10.5 10 0 0 10 10 10 0 C2H2-type zinc finger Ras PF00071.22 CEP14673.1 - 3.9e-66 221.6 0.1 5.2e-66 221.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP14673.1 - 3.4e-35 120.9 0.0 5.3e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP14673.1 - 8.5e-15 54.6 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP14673.1 - 7.2e-06 25.7 0.2 1.8e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEP14673.1 - 1.8e-05 24.3 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEP14673.1 - 5.5e-05 22.6 0.1 6.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP14673.1 - 0.00012 22.1 0.1 0.00058 19.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP14673.1 - 0.00059 19.8 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CEP14673.1 - 0.024 14.5 0.0 0.06 13.1 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CEP14673.1 - 0.027 14.9 0.0 0.049 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CEP14673.1 - 0.045 13.5 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CEP14673.1 - 0.051 13.1 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 CEP14673.1 - 0.055 12.6 0.0 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_5 PF07728.14 CEP14673.1 - 0.094 12.7 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Bmt2 PF11968.8 CEP14676.1 - 0.046 13.6 0.2 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 F-box PF00646.33 CEP14679.1 - 0.0014 18.5 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP14679.1 - 0.0019 18.1 0.2 0.0034 17.2 0.2 1.4 1 0 0 1 1 1 1 F-box-like DUF2897 PF11446.8 CEP14679.1 - 0.64 9.9 1.7 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Tn7_Tnp_TnsA_C PF08721.11 CEP14679.1 - 2.4 8.9 5.5 2.7 8.7 0.0 2.7 3 0 0 3 3 3 0 TnsA endonuclease C terminal Coatomer_WDAD PF04053.14 CEP14680.1 - 3.2e-136 454.9 0.0 5.7e-136 454.1 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CEP14680.1 - 4.5e-136 453.8 0.4 5.8e-136 453.4 0.4 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CEP14680.1 - 1.6e-42 142.6 15.2 7.1e-08 33.0 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP14680.1 - 4.7e-11 42.8 0.5 0.0028 17.9 0.0 6.6 4 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP14680.1 - 0.00074 18.3 7.1 0.15 10.7 0.1 4.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 SGL PF08450.12 CEP14680.1 - 0.0077 15.8 0.0 0.4 10.2 0.0 3.1 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Clathrin PF00637.20 CEP14680.1 - 0.12 12.3 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS HSP70 PF00012.20 CEP14682.1 - 2.8e-263 874.6 8.7 3.2e-263 874.4 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP14682.1 - 2.2e-15 56.3 0.1 1.9e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEP14682.1 - 0.0071 16.1 0.0 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CEP14682.1 - 0.0081 15.5 0.1 0.023 14.0 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 CEP14682.1 - 0.02 14.4 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 CEP14682.1 - 0.047 12.9 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 StbA protein SAPIS-gp6 PF16722.5 CEP14682.1 - 0.068 13.6 3.5 0.09 13.2 1.1 2.4 3 0 0 3 3 3 0 Pathogenicity island protein gp6 in Staphylococcus Pro_isomerase PF00160.21 CEP14683.1 - 3.9e-39 134.4 0.1 4.6e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_H_20C_C PF18088.1 CEP14685.1 - 2.9e-48 164.3 0.3 6e-48 163.3 0.3 1.5 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 CEP14685.1 - 8.4e-11 41.9 0.0 3.2e-09 36.7 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ATG16 PF08614.11 CEP14687.1 - 0.0054 17.0 26.3 0.039 14.2 0.3 4.1 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) Raf1_N PF18578.1 CEP14687.1 - 0.11 12.9 3.4 9.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Rubisco accumulation factor 1 alpha helical domain dCache_1 PF02743.18 CEP14687.1 - 0.13 12.0 7.3 0.26 11.1 7.3 1.6 1 0 0 1 1 1 0 Cache domain Spc7 PF08317.11 CEP14687.1 - 0.47 9.3 29.9 0.076 11.9 14.6 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein Remorin_C PF03763.13 CEP14687.1 - 0.79 9.6 7.2 0.14 12.0 2.4 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region DASH_Dad3 PF08656.10 CEP14687.1 - 0.79 9.8 11.5 0.36 11.0 1.4 3.6 3 2 0 3 3 3 0 DASH complex subunit Dad3 GIT_CC PF16559.5 CEP14687.1 - 1.4 8.9 13.0 1 9.3 1.7 3.8 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 CEP14687.1 - 1.5 9.3 18.7 0.32 11.4 1.8 3.9 3 1 0 3 3 3 0 Snapin/Pallidin DUF948 PF06103.11 CEP14687.1 - 4.1 7.7 14.8 9.5 6.6 0.1 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 CEP14687.1 - 8.7 7.1 14.9 0.39 11.4 0.2 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) Mit_KHE1 PF10173.9 CEP14688.1 - 5.5e-43 147.3 5.1 8.9e-43 146.6 5.1 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pkinase PF00069.25 CEP14689.1 - 9.7e-74 248.1 0.0 2.1e-73 246.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14689.1 - 4.9e-44 150.5 0.0 1.1e-43 149.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP14689.1 - 4.9e-07 29.4 0.0 8.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP14689.1 - 3.9e-05 22.8 0.1 3.9e-05 22.8 0.1 3.1 4 0 0 4 4 4 1 Haspin like kinase domain APH PF01636.23 CEP14689.1 - 0.0007 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEP14689.1 - 0.012 14.9 0.4 0.024 14.0 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox14 PF15522.6 CEP14689.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Novel toxin 14 Choline_kinase PF01633.20 CEP14689.1 - 0.79 9.3 5.4 0.97 9.0 0.0 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF3759 PF12585.8 CEP14690.1 - 0.019 15.0 3.0 0.45 10.6 3.0 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) RNase_T PF00929.24 CEP14692.1 - 6.1e-09 36.6 0.1 3e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Exonuclease zf-C3HC4 PF00097.25 CEP14692.1 - 0.0003 20.6 13.3 0.0003 20.6 13.3 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP14692.1 - 0.00038 20.4 12.4 0.00038 20.4 12.4 3.2 3 1 0 3 3 3 1 RING-type zinc-finger DNA_pol_A_exo1 PF01612.20 CEP14692.1 - 0.0045 16.7 0.0 0.04 13.6 0.0 2.5 1 1 0 1 1 1 1 3'-5' exonuclease zf-C3HC4_4 PF15227.6 CEP14692.1 - 0.0057 16.8 13.4 0.0057 16.8 13.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING UPF0029 PF01205.19 CEP14692.1 - 0.096 13.0 0.0 0.37 11.1 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 zf-C3HC4_2 PF13923.6 CEP14692.1 - 1.1 9.2 25.6 0.06 13.2 15.7 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP14692.1 - 2.7 7.9 19.9 3.3 7.6 13.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP14692.1 - 9.1 6.7 27.1 2.3 8.6 16.3 3.3 3 0 0 3 3 3 0 Ring finger domain zf-RING_6 PF14835.6 CEP14692.1 - 9.5 6.2 13.5 0.39 10.6 7.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Pkinase PF00069.25 CEP14693.1 - 1.9e-64 217.6 0.0 1.2e-63 215.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14693.1 - 4.4e-29 101.5 0.1 1.5e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP14693.1 - 5.4e-07 28.9 2.0 5.7e-07 28.8 1.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP14693.1 - 4.5e-05 23.5 0.3 0.073 13.0 0.3 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP14693.1 - 0.00025 20.5 0.2 0.018 14.4 0.0 2.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP14693.1 - 0.00028 20.3 0.2 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 CEP14693.1 - 0.0066 17.1 0.4 0.019 15.7 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 CEP14693.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CEP14693.1 - 0.03 13.3 0.2 0.054 12.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIA PF03153.13 CEP14693.1 - 0.051 13.6 15.8 0.067 13.2 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 CEP14693.1 - 0.069 11.9 1.3 0.12 11.2 1.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CEP14693.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Presenilin PF01080.17 CEP14693.1 - 1.2 7.9 7.6 1.6 7.4 7.6 1.2 1 0 0 1 1 1 0 Presenilin HD PF01966.22 CEP14695.1 - 7.9e-09 35.8 0.3 1.3e-08 35.1 0.3 1.3 1 0 0 1 1 1 1 HD domain FHA PF00498.26 CEP14696.1 - 6.8e-16 58.4 0.2 1.7e-15 57.1 0.2 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CEP14696.1 - 3.5e-11 42.6 7.2 7.1e-11 41.6 7.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CEP14696.1 - 8.6e-09 35.6 7.7 2.2e-08 34.3 7.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEP14696.1 - 6.2e-05 23.2 4.8 0.00018 21.7 4.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP14696.1 - 6.5e-05 22.7 9.2 0.00015 21.5 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP14696.1 - 0.00014 21.7 7.4 0.00028 20.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP14696.1 - 0.0025 17.7 7.0 0.0053 16.7 7.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEP14696.1 - 0.0035 17.2 4.0 0.0065 16.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP14696.1 - 0.012 15.6 9.3 0.03 14.4 9.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 CEP14696.1 - 0.024 14.5 3.8 0.052 13.4 3.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-ANAPC11 PF12861.7 CEP14696.1 - 0.053 13.6 0.9 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec_GG PF07549.14 CEP14696.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 SecD/SecF GG Motif YpjP PF14005.6 CEP14698.1 - 0.38 10.8 11.0 2.2 8.3 2.2 3.3 1 1 2 3 3 3 0 YpjP-like protein DUF2624 PF11116.8 CEP14698.1 - 0.71 10.8 7.5 11 6.9 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2624) DUF3439 PF11921.8 CEP14700.1 - 0.11 12.5 6.5 0.072 13.1 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) FliD_N PF02465.18 CEP14700.1 - 1.9 9.3 7.3 6.2 7.6 1.8 2.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ASXH PF13919.6 CEP14701.1 - 1.2e-17 64.3 1.9 5.5e-17 62.1 1.9 2.3 1 0 0 1 1 1 1 Asx homology domain PsaN PF05479.11 CEP14702.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) CcmD PF04995.14 CEP14703.1 - 0.00093 19.2 0.2 0.0017 18.4 0.2 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 CEP14703.1 - 0.022 15.6 0.0 0.042 14.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 CEP14703.1 - 0.034 13.9 0.7 0.062 13.1 0.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3149 PF11346.8 CEP14703.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Herpes_gE PF02480.16 CEP14703.1 - 0.067 11.9 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 CEP14703.1 - 0.072 12.9 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2681 PF10883.8 CEP14703.1 - 0.078 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SIT PF15330.6 CEP14703.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Trp_oprn_chp PF09534.10 CEP14703.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CoatB PF10389.9 CEP14703.1 - 0.42 10.5 6.3 0.49 10.3 2.2 2.3 2 0 0 2 2 2 0 Bacteriophage coat protein B Kelch_6 PF13964.6 CEP14704.1 - 6.6e-06 26.2 0.2 7.4 7.0 0.0 5.3 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CEP14704.1 - 1.4e-05 25.0 0.2 2.1 8.4 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP14704.1 - 0.00026 20.5 1.2 2 8.1 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 CEP14704.1 - 0.0037 17.2 0.0 2.5 8.2 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 CEP14704.1 - 0.019 15.0 0.0 33 4.7 0.0 4.1 4 0 0 4 4 4 0 Kelch motif EphA2_TM PF14575.6 CEP14704.1 - 0.04 14.8 0.0 0.078 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 CEP14704.1 - 0.071 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Trp_oprn_chp PF09534.10 CEP14704.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4381 PF14316.6 CEP14704.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CoatB PF10389.9 CEP14704.1 - 0.15 11.9 3.3 0.28 11.1 3.3 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B TMEM51 PF15345.6 CEP14705.1 - 0.035 13.9 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3274 PF11678.8 CEP14705.1 - 0.04 13.2 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3274) MLANA PF14991.6 CEP14705.1 - 0.044 14.1 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A LapA_dom PF06305.11 CEP14705.1 - 0.11 12.3 1.0 0.21 11.5 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ImpA_N PF06812.12 CEP14705.1 - 0.19 11.8 0.3 0.34 11.0 0.3 1.3 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system VSP PF03302.13 CEP14705.1 - 0.31 9.8 0.5 0.47 9.2 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_4 PF13418.6 CEP14706.1 - 0.00019 21.4 4.1 0.12 12.5 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP14706.1 - 0.0006 20.0 3.7 2.6 8.5 0.1 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 CEP14706.1 - 0.0012 18.3 2.3 1.5 8.5 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CEP14706.1 - 0.014 15.3 2.8 3.4 7.8 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Protoglobin PF11563.8 CEP14708.1 - 5.3e-43 146.6 0.0 6.5e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin adh_short PF00106.25 CEP14709.1 - 5.6e-55 185.8 2.5 8.6e-55 185.2 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP14709.1 - 7.3e-51 173.0 0.4 1.1e-50 172.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP14709.1 - 7.5e-19 68.3 1.2 1.2e-18 67.7 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP14709.1 - 3.9e-08 33.0 0.4 8.6e-08 31.9 0.4 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CEP14709.1 - 4.1e-07 29.4 0.2 5.9e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PhoLip_ATPase_N PF16209.5 CEP14709.1 - 7.3e-07 28.8 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal 3HCDH_N PF02737.18 CEP14709.1 - 0.061 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KH_2 PF07650.17 CEP14709.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 KH domain Dimer_Tnp_hAT PF05699.14 CEP14710.1 - 0.029 14.2 0.0 0.19 11.5 0.0 2.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 CEP14710.1 - 0.11 13.0 0.3 0.42 11.2 0.3 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sulfatase PF00884.23 CEP14712.1 - 8.3e-61 206.0 2.0 1.5e-60 205.2 2.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CEP14712.1 - 2.6e-05 24.4 0.3 8.7e-05 22.7 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 CEP14712.1 - 0.0045 15.7 0.3 0.76 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF229) QSregVF_b PF12843.7 CEP14712.1 - 0.033 14.1 0.2 0.087 12.7 0.2 1.7 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Iso_dh PF00180.20 CEP14713.1 - 8.4e-78 261.9 0.0 1e-77 261.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sel1 PF08238.12 CEP14714.1 - 5.4e-93 303.3 86.5 1e-06 29.2 0.6 29.2 29 3 0 29 29 28 18 Sel1 repeat TPR_7 PF13176.6 CEP14714.1 - 5.6e-08 32.3 19.5 0.002 18.0 0.1 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP14714.1 - 3.1e-06 26.9 61.6 0.03 14.4 0.8 16.3 18 1 0 18 18 17 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP14714.1 - 7.7e-05 23.3 39.2 2.3 8.9 0.8 13.1 12 3 3 15 15 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP14714.1 - 0.00041 20.3 32.2 0.043 14.0 0.6 11.5 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP14714.1 - 0.00066 19.9 24.6 13 6.4 0.0 12.5 16 0 0 16 16 14 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP14714.1 - 0.0019 18.8 25.4 4.5 8.4 0.0 11.1 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP14714.1 - 0.0022 17.7 58.3 0.016 15.1 0.6 14.8 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_6 PF13174.6 CEP14714.1 - 0.0022 18.5 47.3 0.18 12.5 0.6 14.1 15 1 0 15 15 14 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP14714.1 - 0.088 13.3 20.6 13 6.3 0.5 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP14714.1 - 0.34 11.2 40.7 2.3 8.5 1.1 11.1 13 0 0 13 13 13 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CEP14714.1 - 4.3 8.2 7.7 1.6e+02 3.4 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP14714.1 - 4.6 7.6 39.6 3.8 7.9 0.2 11.0 11 1 0 11 11 10 0 Tetratricopeptide repeat WWE PF02825.20 CEP14715.1 - 0.0027 18.3 0.0 0.49 11.0 0.0 2.7 2 0 0 2 2 2 2 WWE domain DUF4644 PF15486.6 CEP14715.1 - 0.52 10.0 3.7 0.24 11.1 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Stathmin PF00836.19 CEP14717.1 - 0.06 13.3 10.4 0.43 10.5 6.8 2.2 2 0 0 2 2 2 0 Stathmin family NDC10_II PF16787.5 CEP14725.1 - 1.6e-05 24.1 0.0 0.00012 21.3 0.0 1.9 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CdiI_N PF18228.1 CEP14725.1 - 0.043 13.7 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 CdiI N-terminal domain G-patch PF01585.23 CEP14726.1 - 1.6e-08 34.3 1.5 3.4e-08 33.2 1.5 1.6 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.7 CEP14726.1 - 5.1e-06 26.7 1.5 1e-05 25.7 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP14726.1 - 8.9e-06 25.9 6.9 2e-05 24.8 6.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 CEP14726.1 - 0.0041 17.2 6.5 0.0074 16.4 6.5 1.5 1 0 0 1 1 1 1 DBF zinc finger G-patch_2 PF12656.7 CEP14726.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.1 2 0 0 2 2 2 0 G-patch domain zf-C2H2_2 PF12756.7 CEP14726.1 - 0.04 14.3 8.5 0.044 14.1 7.9 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) IMD PF08397.11 CEP14726.1 - 2.6 7.3 17.0 2.4 7.5 15.7 1.4 1 1 0 1 1 1 0 IRSp53/MIM homology domain O-antigen_lig PF13425.6 CEP14726.1 - 7 5.3 12.0 8.8 5.0 12.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PP-binding PF00550.25 CEP14727.1 - 1.8e-13 50.6 0.3 2.3e-13 50.3 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CEP14727.1 - 3.8e-05 23.8 0.4 4.7e-05 23.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-carrier hnRNP_Q_AcD PF18360.1 CEP14727.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Arf PF00025.21 CEP14728.1 - 2.8e-32 111.6 0.2 1.5e-27 96.2 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CEP14728.1 - 1.1e-12 48.2 0.1 5.9e-10 39.4 0.0 2.1 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP14728.1 - 3.2e-12 46.4 0.0 1.1e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEP14728.1 - 4.6e-09 36.0 0.0 4.7e-07 29.4 0.0 2.0 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CEP14728.1 - 8e-08 31.8 0.7 7.6e-05 22.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEP14728.1 - 9e-07 28.5 0.1 0.0017 17.9 0.0 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEP14728.1 - 3.7e-06 27.0 0.7 0.035 14.2 0.6 2.1 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP14728.1 - 0.0021 17.6 0.0 0.012 15.1 0.0 1.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 CEP14728.1 - 0.0066 16.1 0.4 1 8.9 0.0 2.0 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CEP14728.1 - 0.014 15.4 0.1 1.8 8.6 0.1 2.1 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 CEP14728.1 - 0.019 15.2 0.2 0.8 10.0 0.0 2.1 1 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CEP14728.1 - 0.032 13.8 1.8 0.07 12.7 0.5 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 CEP14728.1 - 0.073 13.6 0.0 0.094 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CEP14728.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ArsC PF03960.15 CEP14728.1 - 0.16 12.0 1.1 0.29 11.2 0.3 1.7 1 1 1 2 2 2 0 ArsC family NDC10_II PF16787.5 CEP14729.1 - 5.9e-35 120.8 0.0 2.2e-33 115.7 0.0 2.3 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP14729.1 - 2.4e-11 43.8 1.4 1.5e-10 41.2 0.1 2.9 3 0 0 3 3 3 1 Transcriptional activator of glycolytic enzymes SWC7 PF17330.2 CEP14729.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 zf-CCHC PF00098.23 CEP14730.1 - 0.01 15.8 19.6 0.094 12.8 7.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP14730.1 - 0.011 15.5 7.1 1.4 8.7 4.7 2.5 2 0 0 2 2 2 0 Zinc knuckle MGC-24 PF05283.11 CEP14730.1 - 2 8.9 6.2 5.9 7.3 6.2 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_2 PF12796.7 CEP14731.1 - 2.1e-14 53.9 1.7 4.6e-09 36.8 0.1 3.3 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP14731.1 - 1.3e-10 41.6 0.4 1.1e-09 38.6 0.1 2.7 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEP14731.1 - 7.6e-10 38.8 7.3 3.8e-06 27.1 0.3 4.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CEP14731.1 - 4.5e-09 35.8 3.6 0.0003 21.0 0.2 5.5 5 1 1 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 CEP14731.1 - 5.3e-06 26.6 1.8 0.078 13.3 0.3 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 CEP14731.1 - 0.0027 17.5 0.7 0.023 14.6 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain BST2 PF16716.5 CEP14731.1 - 0.0055 17.3 14.5 0.56 10.8 3.9 3.6 2 1 1 3 3 3 3 Bone marrow stromal antigen 2 Filament PF00038.21 CEP14731.1 - 0.031 13.8 19.6 0.21 11.1 6.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.12 CEP14731.1 - 0.062 13.8 2.2 17 5.9 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CBS PF00571.28 CEP14731.1 - 0.1 13.1 0.2 0.41 11.1 0.0 2.1 2 0 0 2 2 1 0 CBS domain ADIP PF11559.8 CEP14731.1 - 0.41 10.7 17.7 0.99 9.5 2.1 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TRAF_BIRC3_bd PF16673.5 CEP14731.1 - 0.59 10.0 4.9 8.4 6.3 0.2 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain SlyX PF04102.12 CEP14731.1 - 0.63 10.7 11.3 6.9 7.4 0.1 4.0 3 1 1 4 4 4 0 SlyX Exonuc_VII_L PF02601.15 CEP14731.1 - 0.84 9.2 7.3 1.9 8.0 7.3 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 CEP14731.1 - 0.91 9.0 17.5 6.2 6.3 4.9 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 CEP14731.1 - 1.1 9.9 14.7 1 10.0 2.6 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4094 PF13334.6 CEP14731.1 - 2 8.9 10.9 2.6 8.5 3.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Fez1 PF06818.15 CEP14731.1 - 2.6 8.5 20.2 0.41 11.1 15.6 1.9 2 0 0 2 2 2 0 Fez1 DAO PF01266.24 CEP14732.1 - 1.1e-53 183.1 0.0 1.4e-53 182.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CEP14732.1 - 2.4e-05 24.4 0.1 7.8e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CEP14732.1 - 0.00065 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 CEP14732.1 - 0.0088 15.4 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 CEP14732.1 - 0.012 14.9 0.9 0.075 12.3 1.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP14732.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mqo PF06039.15 CEP14732.1 - 0.084 11.4 0.0 0.66 8.5 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 CEP14732.1 - 0.2 10.7 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein EMP24_GP25L PF01105.24 CEP14733.1 - 8.7e-44 149.6 0.2 1.7e-43 148.7 0.2 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hydrolase_6 PF13344.6 CEP14733.1 - 2e-29 101.7 0.0 1.1e-28 99.3 0.0 2.3 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP14733.1 - 1.7e-18 66.4 0.0 4.4e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP14733.1 - 1e-15 58.6 0.1 2.3e-15 57.4 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP14733.1 - 1.7e-09 38.0 0.0 4.1e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 CEP14733.1 - 1.6e-08 34.9 0.2 1.8e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP14733.1 - 5.7e-05 22.4 0.2 0.00076 18.9 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEP14733.1 - 0.00022 20.9 0.5 0.0014 18.4 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CEP14733.1 - 0.001 18.9 0.3 0.0079 16.0 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_11 PF08976.11 CEP14733.1 - 0.12 13.3 0.0 0.43 11.5 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain RRM_1 PF00076.22 CEP14734.1 - 3e-23 81.4 0.0 8.7e-11 41.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CEP14734.1 - 1.1e-21 75.2 2.1 1.5e-05 24.4 0.0 7.2 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat DUF4523 PF15023.6 CEP14734.1 - 4.5e-07 29.8 1.2 0.0064 16.3 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) DUF2722 PF10846.8 CEP14734.1 - 1.5e-05 24.1 20.7 3.3e-05 23.0 20.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) PAT1 PF09770.9 CEP14734.1 - 2.4e-05 22.9 13.4 0.0077 14.6 12.7 2.3 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 CEP14734.1 - 0.0016 18.1 31.0 0.004 16.8 31.0 1.7 1 0 0 1 1 1 1 Spt20 family Presenilin PF01080.17 CEP14734.1 - 0.0018 17.1 6.8 0.0032 16.3 6.8 1.3 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 CEP14734.1 - 0.0021 18.3 2.7 0.0054 16.9 2.7 1.7 1 0 0 1 1 1 1 DDHD domain RRM_occluded PF16842.5 CEP14734.1 - 0.01 15.7 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif UPF0560 PF10577.9 CEP14734.1 - 0.012 14.2 9.5 0.017 13.6 9.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RRM_8 PF11835.8 CEP14734.1 - 0.034 14.3 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 1 0 RRM-like domain eIF-3_zeta PF05091.12 CEP14734.1 - 0.051 12.5 10.2 0.08 11.9 10.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nab6_mRNP_bdg PF10567.9 CEP14734.1 - 0.053 13.0 0.0 0.053 13.0 0.0 3.0 2 1 1 3 3 2 0 RNA-recognition motif MecA PF05389.12 CEP14734.1 - 0.055 13.1 6.0 0.14 11.8 6.0 1.6 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) MTBP_C PF14920.6 CEP14734.1 - 0.066 13.0 9.9 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 MDM2-binding Tim54 PF11711.8 CEP14734.1 - 0.094 11.5 5.8 0.37 9.5 4.0 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CEP14734.1 - 0.13 12.3 4.2 0.27 11.3 4.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.13 CEP14734.1 - 0.2 12.0 5.5 0.12 12.7 2.9 2.0 2 0 0 2 2 1 0 Brf1-like TBP-binding domain Ndc1_Nup PF09531.10 CEP14734.1 - 0.26 10.0 8.7 0.68 8.5 8.7 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF3_subunit PF08597.10 CEP14734.1 - 0.27 11.1 9.8 0.49 10.3 4.7 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit FAM176 PF14851.6 CEP14734.1 - 0.36 10.5 2.8 0.92 9.2 2.8 1.7 1 0 0 1 1 1 0 FAM176 family PEX11 PF05648.14 CEP14734.1 - 0.37 10.2 2.6 0.8 9.1 2.6 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Connexin PF00029.19 CEP14734.1 - 0.37 10.5 3.9 0.64 9.7 3.9 1.3 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 CEP14734.1 - 0.45 8.6 10.0 0.66 8.0 10.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EOS1 PF12326.8 CEP14734.1 - 0.45 10.4 1.9 0.95 9.4 1.9 1.5 1 0 0 1 1 1 0 N-glycosylation protein SpoIIP PF07454.11 CEP14734.1 - 0.56 9.6 10.9 1.1 8.7 10.9 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3464 PF11947.8 CEP14734.1 - 0.56 9.9 8.9 1.6 8.5 8.9 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RR_TM4-6 PF06459.12 CEP14734.1 - 0.6 9.9 11.0 1.2 8.8 11.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 REC114-like PF15165.6 CEP14734.1 - 0.64 9.7 13.8 1.7 8.4 13.8 1.7 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like DUF2367 PF10164.9 CEP14734.1 - 0.72 10.4 3.5 3.2 8.3 3.5 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) PCM1_C PF15717.5 CEP14734.1 - 0.77 8.4 16.9 0.12 11.1 12.7 1.7 3 0 0 3 3 3 0 Pericentriolar material 1 C terminus CPSF100_C PF13299.6 CEP14734.1 - 0.85 9.8 6.2 2.5 8.2 6.2 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4758 PF15950.5 CEP14734.1 - 0.97 9.8 5.7 16 5.8 2.6 3.4 3 0 0 3 3 3 0 Putative sperm flagellar membrane protein DUF2126 PF09899.9 CEP14734.1 - 0.99 7.4 5.8 1.5 6.8 5.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Orf78 PF06024.12 CEP14734.1 - 1.4 9.3 5.4 3.6 7.9 5.4 1.7 1 0 0 1 1 1 0 Orf78 (ac78) MCU PF04678.13 CEP14734.1 - 1.5 8.8 6.4 1.3 9.1 4.5 1.8 2 0 0 2 2 1 0 Mitochondrial calcium uniporter DUF4175 PF13779.6 CEP14734.1 - 1.6 6.5 25.4 2.8 5.8 25.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folate_carrier PF01770.18 CEP14734.1 - 1.7 7.3 4.6 2.9 6.5 4.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier V_ATPase_I PF01496.19 CEP14734.1 - 1.7 6.5 9.1 3 5.7 9.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Endostatin PF06482.11 CEP14734.1 - 1.8 7.9 12.2 4 6.8 12.2 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3408 PF11888.8 CEP14734.1 - 1.8 8.7 12.0 6.4 6.9 12.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) GET2 PF08690.10 CEP14734.1 - 2.2 7.9 17.2 4.1 7.0 14.4 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 EIIBC-GUT_N PF03612.14 CEP14734.1 - 2.5 7.8 8.9 6.5 6.5 8.9 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 CEP14734.1 - 3.1 8.8 13.9 15 6.6 13.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 CEP14734.1 - 3.4 6.9 10.4 8.6 5.6 10.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 CEP14734.1 - 6.6 6.0 18.5 15 4.9 18.5 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pinin_SDK_memA PF04696.13 CEP14735.1 - 3.3e-27 95.1 22.7 3.3e-27 95.1 22.7 2.2 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 CEP14735.1 - 0.0012 19.0 14.6 0.0012 19.0 14.6 2.7 1 1 1 2 2 2 1 RNSP1-SAP18 binding (RSB) motif DUF1090 PF06476.12 CEP14735.1 - 0.0052 16.9 13.0 0.0052 16.9 13.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1090) DUF2570 PF10828.8 CEP14735.1 - 2.7 7.9 16.6 0.064 13.1 8.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) Myosin_head PF00063.21 CEP14736.1 - 1e-267 889.9 7.2 1.8e-267 889.0 7.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEP14736.1 - 2.4e-17 61.0 26.3 1.4e-05 24.5 0.6 6.0 5 0 0 5 5 5 5 IQ calmodulin-binding motif Myosin_N PF02736.19 CEP14736.1 - 0.0086 15.9 0.3 0.036 13.9 0.1 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CEP14736.1 - 0.0098 16.2 1.2 0.038 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP14736.1 - 0.021 15.2 0.1 0.096 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CEP14736.1 - 0.077 13.4 1.1 1.4 9.3 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 CEP14736.1 - 0.078 12.7 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CEP14736.1 - 0.092 13.3 2.2 0.38 11.3 0.0 3.0 2 0 0 2 2 2 0 ABC transporter DUF2203 PF09969.9 CEP14736.1 - 6.2 7.6 13.5 2.6 8.8 5.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Baculo_LEF-11 PF06385.12 CEP14736.1 - 7.1 7.2 12.9 3.3 8.3 0.5 4.1 3 1 1 4 4 4 0 Baculovirus LEF-11 protein WW PF00397.26 CEP14737.1 - 1.8e-13 50.3 5.1 5.2e-13 48.8 5.1 1.9 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 CEP14737.1 - 0.31 11.0 12.1 0.4 10.6 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF737 PF05300.11 CEP14738.1 - 0.055 13.8 5.6 0.12 12.7 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Seryl_tRNA_N PF02403.22 CEP14738.1 - 1.9 8.7 7.9 1 9.6 3.8 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NAP PF00956.18 CEP14740.1 - 0.042 13.0 0.8 0.047 12.9 0.8 1.0 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF1378 PF07125.11 CEP14741.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Sel_put PF04328.13 CEP14742.1 - 0.00014 21.8 12.9 1.2 9.2 0.5 5.8 6 0 0 6 6 6 3 Selenoprotein, putative zf-met PF12874.7 CEP14742.1 - 0.00043 20.6 7.1 0.0011 19.2 0.9 18.0 18 0 0 18 18 18 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP14742.1 - 0.002 18.3 9.0 0.0067 16.7 1.1 19.0 20 0 0 20 20 20 7 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CEP14742.1 - 0.0048 17.3 3.1 0.0048 17.3 3.1 20.8 22 0 0 22 22 22 7 Zinc finger, C2H2 type zf-Di19 PF05605.12 CEP14742.1 - 0.019 15.2 0.6 0.019 15.2 0.6 15.3 16 4 3 20 20 20 0 Drought induced 19 protein (Di19), zinc-binding CENP-Q PF13094.6 CEP14742.1 - 0.066 13.4 0.3 0.32 11.2 0.3 2.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ta0938 PF11494.8 CEP14742.1 - 1.1 9.5 5.5 0.84 9.9 0.0 3.5 2 1 1 3 3 3 0 Ta0938 MFS_1 PF07690.16 CEP14743.1 - 7.8e-22 77.7 34.2 1.1e-20 73.9 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEP14743.1 - 1e-07 30.9 29.2 6.5e-07 28.3 7.1 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein TssN PF17555.2 CEP14743.1 - 0.0055 16.1 4.6 0.0055 16.1 4.6 3.7 2 2 1 3 3 3 2 Type VI secretion system, TssN B-block_TFIIIC PF04182.12 CEP14744.1 - 4.9e-10 39.4 0.0 3.1e-07 30.4 0.1 3.1 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC CotH PF08757.11 CEP14745.1 - 6e-38 131.2 2.9 9.1e-38 130.6 2.9 1.2 1 0 0 1 1 1 1 CotH kinase protein Med10 PF09748.9 CEP14746.1 - 1.5e-30 105.6 0.1 1.9e-30 105.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4061 PF13270.6 CEP14746.1 - 0.13 12.6 0.3 8.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) VCBS PF13517.6 CEP14747.1 - 1.4e-05 25.5 0.0 0.01 16.4 0.0 3.4 3 1 1 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 CEP14747.1 - 0.0011 18.9 0.1 1.7 8.7 0.0 3.7 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_C PF14782.6 CEP14747.1 - 0.0091 14.8 0.1 0.018 13.8 0.1 1.4 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal Itfg2 PF15907.5 CEP14747.1 - 0.027 13.5 0.1 5.6 5.9 0.0 2.8 2 1 1 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 CEP14747.1 - 0.13 12.4 0.4 0.93 9.7 0.0 2.4 3 0 0 3 3 3 0 FG-GAP repeat PI3_PI4_kinase PF00454.27 CEP14748.1 - 2.5e-48 165.1 0.0 8.2e-48 163.4 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase IMUP PF15761.5 CEP14748.1 - 2.4 8.9 15.6 0.29 11.8 5.4 3.7 3 0 0 3 3 3 0 Immortalisation up-regulated protein TrbC PF04956.13 CEP14749.1 - 0.18 12.1 0.9 0.27 11.5 0.9 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family MFS_2 PF13347.6 CEP14749.1 - 0.38 9.3 2.7 0.51 8.8 2.7 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein RCR PF12273.8 CEP14749.1 - 0.51 11.0 0.0 0.51 11.0 0.0 2.3 3 1 1 4 4 4 0 Chitin synthesis regulation, resistance to Congo red p450 PF00067.22 CEP14750.1 - 2e-67 227.9 0.0 2.7e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA PF00578.21 CEP14751.1 - 1.2e-38 131.8 0.0 3.9e-38 130.2 0.0 2.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP14751.1 - 2.1e-13 50.2 0.0 4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEP14751.1 - 3.2e-12 46.1 0.1 7.2e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LRR_4 PF12799.7 CEP14751.1 - 5.6e-05 23.4 24.8 0.00065 20.0 0.5 6.2 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP14751.1 - 0.00023 20.9 14.8 0.97 9.7 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat TPR_12 PF13424.6 CEP14751.1 - 0.0022 18.2 4.7 0.0032 17.7 0.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_1 PF00560.33 CEP14751.1 - 2 9.3 18.0 1.9 9.4 0.3 7.2 7 0 0 7 7 7 0 Leucine Rich Repeat Dynactin_p22 PF07426.11 CEP14752.1 - 3.2e-44 150.7 4.9 4e-44 150.4 4.9 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Retrotrans_gag PF03732.17 CEP14752.1 - 0.0029 17.8 0.5 2.5 8.4 0.2 2.4 2 0 0 2 2 2 2 Retrotransposon gag protein DASH_Dad2 PF08654.10 CEP14752.1 - 0.0042 17.5 1.5 0.29 11.6 0.2 2.6 2 1 1 3 3 3 1 DASH complex subunit Dad2 DUF1664 PF07889.12 CEP14752.1 - 0.008 16.2 6.7 0.059 13.4 0.7 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 CEP14752.1 - 0.02 14.6 1.6 4.1 7.3 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 FliD_C PF07195.12 CEP14752.1 - 0.026 14.0 7.0 0.49 9.8 0.2 2.9 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF2935 PF11155.8 CEP14752.1 - 0.032 14.5 0.0 0.079 13.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) GIT_CC PF16559.5 CEP14752.1 - 0.036 13.9 3.6 0.06 13.2 0.5 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Nsp1_C PF05064.13 CEP14752.1 - 0.096 12.5 4.3 1.8 8.4 0.3 2.9 2 1 1 3 3 3 0 Nsp1-like C-terminal region NPV_P10 PF05531.12 CEP14752.1 - 0.099 13.1 5.7 12 6.4 5.7 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MitMem_reg PF13012.6 CEP14752.1 - 0.12 12.8 2.3 0.71 10.3 2.3 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Tup_N PF08581.10 CEP14752.1 - 0.12 12.6 4.5 0.58 10.5 0.1 2.9 3 0 0 3 3 3 0 Tup N-terminal Sld3_N PF18523.1 CEP14752.1 - 0.24 11.5 3.5 0.49 10.5 0.2 2.4 2 1 0 2 2 2 0 Sld3 N-terminal domain DUF2205 PF10224.9 CEP14752.1 - 0.24 11.4 3.3 0.2 11.7 0.3 2.3 3 0 0 3 3 3 0 Short coiled-coil protein ANAPC4 PF12896.7 CEP14752.1 - 0.34 10.4 4.2 0.59 9.6 0.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 APG6_N PF17675.1 CEP14752.1 - 0.4 11.2 4.4 3.9 8.0 1.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Thioredoxin_8 PF13905.6 CEP14752.1 - 0.41 11.0 2.5 0.38 11.1 0.2 2.0 3 0 0 3 3 3 0 Thioredoxin-like bZIP_1 PF00170.21 CEP14752.1 - 1.5 8.9 4.7 2.1 8.5 0.6 2.8 3 0 0 3 3 3 0 bZIP transcription factor Fib_alpha PF08702.10 CEP14752.1 - 2.8 8.1 7.0 4.4 7.5 1.0 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PI3_PI4_kinase PF00454.27 CEP14753.1 - 7.8e-49 166.7 0.0 1.8e-48 165.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CEP14753.1 - 7.8e-10 38.5 9.4 7.8e-10 38.5 9.4 3.0 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 CEP14753.1 - 6.2e-08 32.3 0.4 2.2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 FATC domain TPR_8 PF13181.6 CEP14753.1 - 0.015 15.4 4.1 0.34 11.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP14753.1 - 0.066 13.4 1.8 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4777 PF16007.5 CEP14753.1 - 0.11 12.7 0.3 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) UME PF08064.13 CEP14753.1 - 1.8 8.5 6.9 2.5 8.1 0.1 4.5 5 0 0 5 5 5 0 UME (NUC010) domain RVT_1 PF00078.27 CEP14754.1 - 3.2e-19 69.3 0.0 8.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP14754.1 - 0.00024 21.6 0.7 0.0046 17.5 0.1 2.8 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP14754.1 - 0.00035 20.3 0.1 0.002 17.9 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP14754.1 - 0.00038 21.0 0.6 0.0036 17.9 0.1 2.6 2 1 1 3 3 3 1 Aspartyl protease zf-CCHC PF00098.23 CEP14754.1 - 0.00044 20.2 2.2 0.00044 20.2 2.2 2.3 2 0 0 2 2 2 1 Zinc knuckle DENN PF02141.21 CEP14755.1 - 2.4e-23 83.0 0.1 1.8e-13 50.8 0.0 2.6 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CEP14755.1 - 8.2e-15 55.3 3.2 2.9e-14 53.5 3.2 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 CEP14755.1 - 1.2e-14 54.0 3.3 3e-14 52.7 3.3 1.7 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.22 CEP14755.1 - 0.57 10.1 6.0 1.3 9.0 6.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Allantoicase PF03561.15 CEP14756.1 - 4.3e-55 185.6 0.0 7.1e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat F-box-like PF12937.7 CEP14757.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP14757.1 - 0.052 13.4 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 F-box domain zf-C2H2 PF00096.26 CEP14758.1 - 3.2e-06 27.3 8.4 0.0012 19.2 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP14758.1 - 0.00014 22.4 7.5 0.06 14.2 1.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP14758.1 - 0.0089 16.0 0.3 0.028 14.4 0.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEP14758.1 - 0.024 14.4 2.1 0.024 14.4 2.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CEP14758.1 - 0.035 14.5 2.6 0.035 14.5 2.6 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 CEP14758.1 - 0.047 13.6 0.6 0.13 12.2 0.6 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-met PF12874.7 CEP14758.1 - 0.27 11.7 0.1 0.27 11.7 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 CEP14758.1 - 1.4 9.1 3.3 2.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain DUF3128 PF11326.8 CEP14759.1 - 3.7e-25 88.1 4.0 3.7e-25 88.1 4.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) LSM PF01423.22 CEP14759.1 - 2.8e-17 62.1 2.1 4.4e-17 61.5 2.1 1.3 1 0 0 1 1 1 1 LSM domain UPF0203 PF05254.12 CEP14759.1 - 0.0051 17.0 5.8 0.01 16.0 5.8 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) SM-ATX PF14438.6 CEP14759.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain Tmemb_14 PF03647.13 CEP14760.1 - 9.8e-29 99.9 4.4 1.1e-28 99.8 4.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 CEP14760.1 - 0.0038 17.5 0.9 0.0098 16.2 0.9 1.8 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Transglut_core2 PF13369.6 CEP14760.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Gram_pos_anchor PF00746.21 CEP14760.1 - 5.8 7.0 0.0 5.8 7.0 0.0 3.6 4 0 0 4 4 4 0 LPXTG cell wall anchor motif CybS PF05328.12 CEP14761.1 - 1.7e-36 124.8 0.0 2.3e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DTW PF03942.15 CEP14762.1 - 5.1e-30 104.7 0.0 7.7e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 DTW domain Glyco_hydro_20 PF00728.22 CEP14763.1 - 6.1e-92 308.7 0.5 8.7e-92 308.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CEP14763.1 - 2.8e-23 83.1 0.1 9.1e-23 81.4 0.1 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CEP14763.1 - 2.3e-06 28.4 0.1 3.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 CEP14763.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 GST_N_3 PF13417.6 CEP14764.1 - 3.4e-11 43.4 0.0 6.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP14764.1 - 9.2e-10 38.6 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEP14764.1 - 9e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEP14764.1 - 2.7e-08 33.7 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP14764.1 - 1.6e-07 31.4 0.1 3.7e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CEP14764.1 - 1.5e-05 25.2 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GATA PF00320.27 CEP14765.1 - 1.9e-16 59.3 4.6 3.2e-16 58.6 4.6 1.4 1 0 0 1 1 1 1 GATA zinc finger CDC45 PF02724.14 CEP14765.1 - 0.0057 15.0 7.2 0.007 14.7 7.2 1.2 1 0 0 1 1 1 1 CDC45-like protein FAM163 PF15069.6 CEP14765.1 - 0.02 15.3 1.2 0.02 15.3 1.2 2.1 2 0 0 2 2 2 0 FAM163 family SDA1 PF05285.12 CEP14765.1 - 0.15 11.4 16.3 0.28 10.6 16.3 1.5 1 0 0 1 1 1 0 SDA1 zf-ribbon_3 PF13248.6 CEP14765.1 - 0.22 11.0 2.3 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3027 PF11228.8 CEP14765.1 - 0.31 11.1 5.5 1 9.4 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3027) YL1 PF05764.13 CEP14765.1 - 0.32 11.1 19.6 1.7 8.7 19.6 1.9 1 1 0 1 1 1 0 YL1 nuclear protein zinc_ribbon_2 PF13240.6 CEP14765.1 - 0.53 10.1 4.1 5.2 6.9 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NOA36 PF06524.12 CEP14765.1 - 1.8 7.8 19.0 3.1 7.0 19.0 1.4 1 0 0 1 1 1 0 NOA36 protein PH_12 PF16457.5 CEP14765.1 - 2.6 8.6 6.5 0.72 10.4 2.5 2.3 2 2 0 2 2 2 0 Pleckstrin homology domain Nop14 PF04147.12 CEP14765.1 - 2.8 6.1 23.8 4.1 5.5 23.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CEP14765.1 - 3.1 7.0 24.0 4.5 6.5 24.0 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CEP14765.1 - 3.3 5.7 20.9 3.3 5.7 19.5 1.6 2 0 0 2 2 2 0 DNA polymerase phi DUF4097 PF13349.6 CEP14766.1 - 3.5e-09 36.4 28.5 1.2e-05 24.8 12.4 3.8 2 1 0 2 2 2 2 Putative adhesin VWD PF00094.25 CEP14766.1 - 6.1 7.1 10.6 1.6 8.9 0.1 4.1 4 1 0 5 5 5 0 von Willebrand factor type D domain FYRN PF05964.14 CEP14767.1 - 8.2e-19 67.2 0.3 2.3e-18 65.8 0.3 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CEP14767.1 - 1.6e-17 63.4 0.0 3.9e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus O-FucT PF10250.9 CEP14768.1 - 4e-19 69.5 0.0 9.7e-06 25.5 0.0 3.6 3 2 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase LON_substr_bdg PF02190.16 CEP14769.1 - 2.5e-13 50.4 0.0 3.8e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 CEP14769.1 - 4.6e-10 39.2 10.1 9.6e-10 38.2 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP14769.1 - 3e-09 37.0 9.3 9e-09 35.5 9.3 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CEP14769.1 - 4.5e-09 36.0 6.9 9.3e-09 35.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP14769.1 - 1.1e-08 34.9 11.5 3e-08 33.5 11.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP14769.1 - 1.5e-08 34.3 10.0 3.3e-08 33.3 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP14769.1 - 2.8e-08 33.6 9.0 5.4e-08 32.7 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CEP14769.1 - 1.2e-07 31.8 9.5 2.3e-07 30.8 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEP14769.1 - 1.3e-06 28.2 7.6 2.7e-06 27.1 7.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CEP14769.1 - 0.0014 18.4 6.1 0.0037 17.0 6.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CEP14769.1 - 0.0024 18.0 5.6 0.0056 16.8 5.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CEP14769.1 - 0.0046 16.7 4.5 0.023 14.4 4.5 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CEP14769.1 - 0.008 16.4 4.9 0.023 14.9 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-NOSIP PF15906.5 CEP14769.1 - 0.065 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_4 PF14570.6 CEP14769.1 - 0.075 12.8 8.4 0.034 13.9 5.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CEP14769.1 - 0.12 12.2 3.7 0.24 11.3 3.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 CEP14769.1 - 0.17 12.0 3.1 0.66 10.1 3.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC5 PF06221.13 CEP14769.1 - 2.5 8.2 7.2 0.43 10.6 2.5 2.1 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type DUF410 PF04190.13 CEP14770.1 - 7e-74 248.9 0.1 8.6e-74 248.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_12 PF13424.6 CEP14770.1 - 0.04 14.2 1.0 0.077 13.3 0.5 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4363 PF14276.6 CEP14770.1 - 0.058 13.5 0.2 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Ank_4 PF13637.6 CEP14771.1 - 1.8e-21 76.2 2.6 2.1e-09 37.7 0.1 5.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP14771.1 - 4.4e-16 59.2 0.3 7.1e-07 29.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP14771.1 - 5.7e-15 53.9 4.4 3.8e-06 26.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CEP14771.1 - 3.9e-14 52.4 7.2 1.7e-06 28.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEP14771.1 - 2e-13 50.3 1.6 2.7e-06 27.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DNA_mis_repair PF01119.19 CEP14772.1 - 3.6e-16 58.9 1.0 8.8e-16 57.6 1.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CEP14772.1 - 4.5e-12 46.0 1.4 1e-11 44.8 0.8 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEP14772.1 - 1e-05 26.0 0.9 6.4e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RVT PF13966.6 CEP14773.1 - 0.00073 20.2 0.7 0.00073 20.2 0.7 1.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase p450 PF00067.22 CEP14774.1 - 9.2e-80 268.6 0.0 1.1e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Desmo_N PF06771.11 CEP14774.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Mito_carr PF00153.27 CEP14775.1 - 8.9e-80 262.7 0.1 3.2e-28 97.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP14775.1 - 0.00032 19.9 0.5 0.078 12.1 0.1 3.3 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Pex24p PF06398.11 CEP14776.1 - 3.8e-36 124.8 10.2 6.9e-36 124.0 10.2 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4112 PF13430.6 CEP14776.1 - 3.5e-26 91.5 2.5 5e-26 91.0 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) DUF2502 PF10697.9 CEP14776.1 - 0.0061 16.9 5.8 0.0061 16.9 5.8 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2502) SPARC_Ca_bdg PF10591.9 CEP14776.1 - 3.5 8.0 6.3 3.5 8.0 0.6 2.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3337 PF11816.8 CEP14777.1 - 0.052 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Aminotran_3 PF00202.21 CEP14778.1 - 7.3e-117 390.5 0.0 9.9e-117 390.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Serine_rich PF08824.10 CEP14778.1 - 0.0081 16.2 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Serine rich protein interaction domain Aminotran_1_2 PF00155.21 CEP14778.1 - 0.019 14.1 0.0 0.086 12.0 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II PPTA PF01239.22 CEP14779.1 - 2.5e-42 141.4 20.7 2.9e-09 36.3 0.2 6.6 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat CN_hydrolase PF00795.22 CEP14779.1 - 3.1e-36 125.1 0.0 5.2e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Torus PF16131.5 CEP14780.1 - 7e-22 78.2 1.6 7e-22 78.2 1.6 3.2 2 1 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CEP14780.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CEP14780.1 - 0.0013 18.7 1.1 0.0024 17.9 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain YjbH PF06082.11 CEP14780.1 - 0.015 14.2 3.4 0.02 13.7 3.4 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH AstE_AspA PF04952.14 CEP14780.1 - 0.024 13.7 0.5 7.9 5.5 0.0 2.6 2 1 1 3 3 3 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-CCCH_4 PF18044.1 CEP14780.1 - 0.57 10.1 1.9 0.92 9.4 1.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger RRP7 PF12923.7 CEP14780.1 - 4 7.6 14.6 1.6 8.9 11.8 1.9 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF4536 PF15055.6 CEP14781.1 - 4.1e-05 23.7 3.3 7e-05 23.0 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) Peptidase_A22B PF04258.13 CEP14782.1 - 5.8e-32 111.3 13.9 1.5e-19 70.6 0.7 2.1 1 1 1 2 2 2 2 Signal peptide peptidase Transformer PF06495.11 CEP14782.1 - 0.62 10.1 22.2 0.1 12.7 3.9 2.7 3 0 0 3 3 3 0 Fruit fly transformer protein TMEM51 PF15345.6 CEP14782.1 - 1.7 8.4 5.0 0.19 11.5 0.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Corona_nucleoca PF00937.18 CEP14782.1 - 8 5.4 13.7 6.1 5.8 3.1 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein RPA_C PF08784.11 CEP14783.1 - 0.0013 19.3 0.2 0.0031 18.1 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CEP14783.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TBPIP PF07106.13 CEP14783.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Carboxyl_trans PF01039.22 CEP14784.1 - 6.9e-188 625.3 0.0 8.1e-188 625.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CEP14784.1 - 0.00047 19.7 0.9 0.0034 16.9 0.0 2.4 2 1 1 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Questin_oxidase PF14027.6 CEP14785.1 - 2.6e-31 109.4 0.0 3.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Pkinase PF00069.25 CEP14786.1 - 8.2e-53 179.4 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14786.1 - 3.3e-37 128.2 0.0 4.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP14786.1 - 1e-05 24.5 0.2 3.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEP14786.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEP14786.1 - 0.062 12.9 0.0 0.33 10.5 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CEP14786.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Baculo_PEP_C PF04513.12 CEP14787.1 - 0.0053 16.8 3.6 0.0053 16.8 3.6 1.7 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.13 CEP14787.1 - 0.022 14.7 1.6 0.032 14.1 0.3 1.8 2 0 0 2 2 2 0 Transcriptional activator Nop PF01798.18 CEP14787.1 - 0.023 14.2 1.4 0.11 12.0 1.4 1.8 1 1 0 1 1 1 0 snoRNA binding domain, fibrillarin Vac_Fusion PF02346.16 CEP14787.1 - 0.034 13.8 1.3 2.4 7.9 0.1 2.9 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Nup54 PF13874.6 CEP14787.1 - 0.048 13.8 1.3 0.063 13.4 1.3 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ZYG-11_interact PF05884.12 CEP14787.1 - 0.057 12.8 1.9 0.069 12.6 1.9 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 MRPL52 PF18699.1 CEP14787.1 - 0.066 13.4 3.9 1.7 8.9 0.5 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Cep57_MT_bd PF06657.13 CEP14787.1 - 0.1 13.0 3.3 5.8 7.4 0.4 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4168 PF13767.6 CEP14787.1 - 0.11 13.7 5.0 0.19 12.9 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) Laminin_II PF06009.12 CEP14787.1 - 0.11 12.5 3.0 2.8 8.0 0.1 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 CEP14787.1 - 0.16 12.0 2.5 1.1 9.3 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 CEP14787.1 - 0.44 10.4 7.1 0.3 11.0 3.4 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 CEP14787.1 - 0.56 10.4 7.6 0.77 9.9 7.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Chordopox_A30L PF06015.12 CEP14787.1 - 1.7 8.6 9.6 0.58 10.0 0.9 2.4 2 1 0 2 2 2 0 Chordopoxvirus A30L protein NUDIX PF00293.28 CEP14788.1 - 0.0011 19.0 0.0 0.053 13.6 0.0 2.7 1 1 0 1 1 1 1 NUDIX domain Calici_MSP PF05752.11 CEP14789.1 - 0.12 12.2 0.6 0.27 11.0 0.6 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF4558 PF15104.6 CEP14789.1 - 2.1 8.5 15.0 0.43 10.7 4.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4558) zf-C2H2 PF00096.26 CEP14790.1 - 2.9e-09 36.8 8.5 3e-05 24.2 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP14790.1 - 1.4e-06 28.5 1.0 1.4e-06 28.5 1.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP14790.1 - 0.00067 20.3 6.8 0.095 13.6 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP14790.1 - 0.0032 17.7 0.5 0.01 16.1 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP14790.1 - 0.01 16.4 1.0 0.2 12.3 0.1 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain OrsD PF12013.8 CEP14790.1 - 0.84 10.1 4.6 17 5.9 0.1 2.9 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D C2-set PF05790.15 CEP14790.1 - 1.3 9.2 7.6 2.4 8.4 0.4 3.1 3 0 0 3 3 3 0 Immunoglobulin C2-set domain Cnd1 PF12717.7 CEP14791.1 - 5.1e-53 179.4 10.0 1.6e-51 174.5 1.4 4.0 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CEP14791.1 - 5.9e-42 143.3 0.1 2.8e-41 141.1 0.1 2.3 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 CEP14791.1 - 1.5e-09 38.1 0.2 9.9e-05 22.7 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CEP14791.1 - 6.2e-07 29.1 2.8 0.53 10.7 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 CEP14791.1 - 7.4e-06 26.1 3.7 0.11 12.7 0.0 4.9 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CEP14791.1 - 3.4e-05 22.6 13.6 0.00011 20.9 0.3 4.4 4 1 1 6 6 6 2 Adaptin N terminal region Cnd3 PF12719.7 CEP14791.1 - 0.00076 18.8 1.2 0.00076 18.8 1.2 4.1 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm_2 PF04826.13 CEP14791.1 - 0.013 15.0 2.8 0.014 14.8 0.3 2.3 2 0 0 2 2 2 0 Armadillo-like YtzH PF14165.6 CEP14791.1 - 0.017 15.5 1.1 0.11 12.9 0.0 3.0 3 0 0 3 3 3 0 YtzH-like protein HEAT_EZ PF13513.6 CEP14791.1 - 0.019 15.5 0.7 2.8 8.5 0.0 4.6 4 1 1 5 5 5 0 HEAT-like repeat zf-C2H2_2 PF12756.7 CEP14792.1 - 8.7e-33 112.7 13.0 6.2e-27 93.9 0.9 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEP14792.1 - 7.6e-10 38.8 20.8 1.3e-07 31.7 4.8 4.3 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP14792.1 - 2.5e-07 30.8 3.5 2.5e-07 30.8 3.5 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 CEP14792.1 - 0.0021 18.3 2.4 0.91 9.7 0.3 2.7 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 CEP14792.1 - 0.0028 18.3 16.8 0.09 13.7 0.4 4.5 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP14792.1 - 0.0095 16.3 17.4 0.49 11.0 1.0 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type C1_4 PF07975.12 CEP14792.1 - 1.7 9.0 6.8 8.8 6.6 0.2 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain Papo_T_antigen PF02380.15 CEP14792.1 - 1.8 8.7 6.7 1.9 8.7 0.2 3.2 4 0 0 4 4 4 0 T-antigen specific domain zf-C2H2_6 PF13912.6 CEP14792.1 - 8.6 6.5 10.6 0.9 9.6 1.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.25 CEP14794.1 - 1.8e-87 293.7 0.1 3.4e-87 292.8 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.27 CEP14794.1 - 3.4e-64 212.8 2.2 4.9e-22 77.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C58 PF03543.14 CEP14794.1 - 0.13 12.0 0.6 0.29 10.8 0.6 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen PFK PF00365.20 CEP14795.1 - 9e-195 645.4 5.9 1.5e-107 359.1 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 CEP14795.1 - 0.03 14.0 0.2 0.14 11.7 0.2 2.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pfk_N PF18468.1 CEP14795.1 - 0.03 14.7 0.1 0.058 13.8 0.1 1.4 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast PcrB PF01884.17 CEP14795.1 - 0.12 11.8 0.2 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PcrB family SLATT_5 PF18160.1 CEP14796.1 - 0.00032 20.1 0.6 0.00032 20.1 0.6 1.9 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 PHO4 PF01384.20 CEP14796.1 - 6.5 5.7 8.6 5.9 5.8 0.3 2.3 1 1 1 2 2 2 0 Phosphate transporter family DDE_3 PF13358.6 CEP14798.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease INT_SG_DDX_CT_C PF15300.6 CEP14798.1 - 0.039 13.7 0.2 0.09 12.6 0.2 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DDE_3 PF13358.6 CEP14799.1 - 4.5e-17 62.2 0.1 6.7e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 CEP14799.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP14799.1 - 0.043 12.8 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain ERCC3_RAD25_C PF16203.5 CEP14800.1 - 7.1e-63 212.1 0.1 1.9e-37 128.8 0.1 2.4 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CEP14800.1 - 7.9e-22 78.1 0.0 1.6e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CEP14800.1 - 2.1e-09 36.6 0.0 3.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP14800.1 - 5e-09 36.5 0.3 6.7e-08 32.9 0.1 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP14800.1 - 5.2e-06 26.3 0.0 9.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CEP14800.1 - 9.3e-05 22.2 0.0 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 CEP14800.1 - 0.0012 17.8 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF2461 PF09365.10 CEP14801.1 - 1.6e-61 207.9 0.2 1.6e-61 207.9 0.2 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Merozoite_SPAM PF07133.11 CEP14801.1 - 3.6 7.5 28.2 5.9 6.8 28.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pex14_N PF04695.13 CEP14801.1 - 3.9 8.1 11.6 7.3 7.2 11.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PI3K_1B_p101 PF10486.9 CEP14801.1 - 5.2 4.7 8.8 6.6 4.4 8.8 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Seipin PF06775.14 CEP14802.1 - 2e-53 181.4 4.6 3.3e-53 180.7 4.6 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FAD_binding_3 PF01494.19 CEP14802.1 - 5.3e-19 68.7 0.0 1.1e-09 38.0 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 CEP14802.1 - 0.00021 21.0 0.1 0.00076 19.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 CEP14802.1 - 0.00027 20.1 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 CEP14802.1 - 0.0005 19.4 0.0 0.0024 17.2 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEP14802.1 - 0.0036 16.4 0.0 0.06 12.4 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CEP14802.1 - 0.0049 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CEP14802.1 - 0.01 14.7 0.1 0.025 13.5 0.1 1.6 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 CEP14802.1 - 0.026 15.1 0.1 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEP14802.1 - 0.08 12.0 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CEP14802.1 - 0.18 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CEP14802.1 - 0.21 11.9 0.2 0.46 10.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEP14802.1 - 0.21 10.3 0.2 0.4 9.3 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein IMS PF00817.20 CEP14803.1 - 7.3e-47 159.1 0.2 1.9e-46 157.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CEP14803.1 - 2.9e-12 47.3 0.0 8.7e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CEP14803.1 - 3.3e-05 24.0 0.0 0.00013 22.1 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 CEP14803.1 - 0.0005 19.8 0.5 0.0011 18.6 0.5 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 MazG_C PF18722.1 CEP14803.1 - 0.022 14.3 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 MazG C-terminal domain Trm112p PF03966.16 CEP14803.1 - 0.15 12.6 0.2 0.44 11.1 0.2 1.8 1 0 0 1 1 1 0 Trm112p-like protein AAA_18 PF13238.6 CEP14804.1 - 3e-06 27.8 0.0 5.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 CEP14804.1 - 1e-05 25.7 0.0 2.9e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 CEP14804.1 - 0.0011 19.3 0.1 0.024 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP14804.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CEP14804.1 - 0.0097 15.8 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase NACHT PF05729.12 CEP14804.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CPT PF07931.12 CEP14804.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.29 CEP14804.1 - 0.029 14.8 0.1 0.047 14.1 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA_lig_kinase PF08303.11 CEP14804.1 - 0.05 13.7 0.1 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_16 PF13191.6 CEP14804.1 - 0.063 13.7 0.0 0.083 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 CEP14804.1 - 0.066 11.1 0.1 0.089 10.7 0.1 1.1 1 0 0 1 1 1 0 Helicase PRK PF00485.18 CEP14804.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 CEP14804.1 - 0.2 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 CEP14805.1 - 2.2e-26 92.2 0.0 5.1e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CEP14805.1 - 8.4e-07 29.5 0.1 0.0012 19.3 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain Y_phosphatase2 PF03162.13 CEP14805.1 - 0.00026 20.6 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP14805.1 - 0.003 17.2 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CEP14805.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Med23 PF11573.8 CEP14805.1 - 0.018 12.7 0.0 0.025 12.2 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Y_phosphatase3 PF13350.6 CEP14805.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.6 CEP14805.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half AIP3 PF03915.13 CEP14806.1 - 0.002 17.3 3.0 0.0021 17.2 3.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 TFIID-18kDa PF02269.16 CEP14806.1 - 0.0056 16.7 0.2 0.0089 16.0 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF641 PF04859.12 CEP14806.1 - 0.0081 16.5 2.4 0.0081 16.5 2.4 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF16 PF01519.16 CEP14806.1 - 0.031 14.8 3.2 0.031 14.8 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 CEP14806.1 - 0.062 13.4 6.3 0.53 10.4 0.5 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HNH_repeat PF18780.1 CEP14806.1 - 0.14 12.0 0.1 1.2 9.0 0.3 2.2 2 0 0 2 2 2 0 Homing endonuclease repeat Sec20 PF03908.13 CEP14806.1 - 0.16 11.9 3.6 0.21 11.5 1.5 2.0 1 1 1 2 2 2 0 Sec20 Retrotrans_gag PF03732.17 CEP14807.1 - 7.2e-07 29.4 1.0 1.1e-06 28.8 1.0 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein PIF1 PF05970.14 CEP14809.1 - 0.028 13.6 0.2 0.039 13.1 0.2 1.2 1 0 0 1 1 1 0 PIF1-like helicase UvrD_C_2 PF13538.6 CEP14809.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 CEP14810.1 - 3.2e-49 167.8 15.3 3.2e-49 167.8 15.3 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP14810.1 - 4e-14 52.3 2.0 4e-14 52.3 2.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CEP14810.1 - 1.6e-08 33.5 5.9 2.5e-08 32.8 5.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 CEP14810.1 - 8.1e-07 28.3 4.3 0.00042 19.3 0.4 2.8 3 0 0 3 3 3 2 Sugar-tranasporters, 12 TM OATP PF03137.20 CEP14810.1 - 0.0013 17.1 5.0 0.0013 17.1 5.0 3.0 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 CEP14810.1 - 0.0038 15.7 1.2 0.0065 14.9 1.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 CEP14810.1 - 0.009 14.9 0.2 0.009 14.9 0.2 3.0 2 2 1 3 3 3 2 MFS_1 like family HLH PF00010.26 CEP14811.1 - 9.8e-12 44.6 0.4 2.1e-11 43.6 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NOA36 PF06524.12 CEP14811.1 - 0.54 9.5 12.4 0.88 8.8 12.4 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CEP14811.1 - 3.1 8.2 15.1 6.7 7.2 15.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 CEP14811.1 - 6.2 7.1 10.6 15 5.9 10.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 CEP14811.1 - 8.9 6.0 20.2 2.3 7.9 16.2 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.26 CEP14812.1 - 1.6e-12 47.1 12.0 4.3e-06 26.9 4.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP14812.1 - 5.8e-07 29.8 16.6 0.0021 18.7 0.8 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP14812.1 - 5.3e-06 26.6 21.0 1e-05 25.7 2.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CEP14812.1 - 0.0052 17.0 3.8 0.011 15.9 3.8 1.5 1 1 0 1 1 1 1 Aberrant zinc-finger zf-LYAR PF08790.11 CEP14812.1 - 0.67 9.9 4.9 14 5.7 1.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-met PF12874.7 CEP14812.1 - 1.4 9.4 14.5 2.1 8.9 1.7 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CEP14812.1 - 3.6 7.4 14.0 12 5.7 3.6 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 CEP14812.1 - 4.2 8.1 8.1 1.2 9.8 0.6 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CEP14812.1 - 5.2 7.5 7.9 1 9.7 1.9 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) LMBR1 PF04791.16 CEP14813.1 - 1.4e-20 73.7 16.5 3.6e-19 69.1 3.3 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein Bap31 PF05529.12 CEP14813.1 - 1.6 8.6 5.5 0.38 10.6 1.6 2.0 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region DUF4131 PF13567.6 CEP14813.1 - 1.8 8.2 16.7 0.079 12.6 0.3 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Mit_ribos_Mrp51 PF11709.8 CEP14814.1 - 1.3e-12 48.0 11.8 2.1e-07 30.9 7.7 3.9 1 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit Paramyxo_C PF01692.18 CEP14814.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Paramyxovirus non-structural protein C DUF3759 PF12585.8 CEP14815.1 - 9.9e-16 57.5 10.3 2.2e-15 56.4 10.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.6 CEP14815.1 - 1.1e-05 26.1 0.0 0.0046 17.6 0.0 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like DUF3090 PF11290.8 CEP14815.1 - 0.21 11.4 1.8 0.43 10.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) MULE PF10551.9 CEP14817.1 - 0.00046 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain PAT1 PF09770.9 CEP14819.1 - 7.1 4.8 16.4 7.5 4.7 16.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.24 CEP14820.1 - 1.2e-52 179.3 21.0 1.5e-52 179.0 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP14820.1 - 2.1e-25 89.4 33.8 1.5e-23 83.3 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NTPase_I-T PF01931.18 CEP14820.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 Aldolase_II PF00596.21 CEP14821.1 - 3.9e-47 160.6 0.0 4.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Bromo_TP PF07524.13 CEP14822.1 - 1.3e-15 57.2 0.0 2.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 CEP14822.1 - 4.7e-09 36.0 1.5 9.4e-09 35.0 1.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP14822.1 - 0.00016 21.2 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 PHD-finger Bromo_TP_like PF17027.5 CEP14822.1 - 0.00045 20.4 0.5 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Histone-fold protein Thioredoxin PF00085.20 CEP14823.1 - 1.3e-30 105.4 0.6 2.9e-26 91.4 0.2 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CEP14823.1 - 1.1e-19 71.1 0.3 4.7e-16 59.2 0.3 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Calsequestrin PF01216.17 CEP14823.1 - 7.6e-08 31.8 0.1 2.7e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 CEP14823.1 - 1.5e-06 28.6 0.1 0.0028 18.1 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP14823.1 - 1.7e-06 28.3 0.5 0.045 14.1 0.0 4.3 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 CEP14823.1 - 8.7e-05 22.0 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CEP14823.1 - 0.00086 19.3 0.0 0.0039 17.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.6 CEP14823.1 - 0.051 13.8 0.5 0.34 11.1 0.1 2.5 3 0 0 3 3 3 0 Thioredoxin-like FancD2 PF14631.6 CEP14823.1 - 0.073 10.5 0.0 0.1 10.0 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Thioredoxin_9 PF14595.6 CEP14823.1 - 0.45 10.3 2.5 0.52 10.1 0.0 2.4 4 0 0 4 4 4 0 Thioredoxin 6PGD PF00393.19 CEP14824.1 - 1.6e-126 421.6 0.0 2.1e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEP14824.1 - 7.6e-53 178.9 0.0 1.1e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CEP14824.1 - 0.014 16.0 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 CEP14824.1 - 0.062 13.6 0.0 0.49 10.6 0.0 2.4 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NuiA PF07924.11 CEP14825.1 - 0.00011 22.6 1.6 0.00087 19.7 1.6 2.0 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein FMO-like PF00743.19 CEP14826.1 - 9.8e-18 63.9 2.0 1.5e-16 59.9 2.1 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CEP14826.1 - 4.9e-10 39.1 3.0 1.1e-08 34.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEP14826.1 - 2.6e-09 37.2 0.5 7.4e-09 35.7 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CEP14826.1 - 1.1e-07 31.5 0.0 7.3e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP14826.1 - 0.00011 21.6 1.8 0.0022 17.3 1.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP14826.1 - 0.0015 17.8 0.3 0.041 13.1 0.1 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CEP14826.1 - 0.0021 17.7 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP14826.1 - 0.0027 17.7 2.1 0.57 10.2 0.0 3.1 3 1 0 3 3 3 2 FAD-NAD(P)-binding DUF3403 PF11883.8 CEP14826.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) GIDA PF01134.22 CEP14826.1 - 0.14 11.2 1.8 3.7 6.5 0.2 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 CEP14826.1 - 0.29 11.7 3.6 3.4 8.3 0.5 3.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase CUE PF02845.16 CEP14827.1 - 7.5e-07 28.7 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 CEP14827.1 - 0.0011 18.9 6.7 0.0019 18.1 6.7 1.4 1 1 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 CEP14827.1 - 0.0012 18.9 4.9 0.0021 18.0 4.9 1.5 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.31 CEP14827.1 - 0.0029 17.5 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpb4 PF03874.16 CEP14828.1 - 6.4e-21 74.9 2.9 8.9e-21 74.5 2.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PAR1 PF06521.11 CEP14830.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 PAR1 protein Mak16 PF04874.14 CEP14832.1 - 1.6 9.3 12.4 8.3 7.1 3.0 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region FAM76 PF16046.5 CEP14832.1 - 5.5 6.3 7.6 5.2 6.3 1.9 2.3 2 0 0 2 2 2 0 FAM76 protein DUF4611 PF15387.6 CEP14832.1 - 8.3 6.7 10.9 0.68 10.2 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LIM PF00412.22 CEP14833.1 - 0.7 10.2 2.4 22 5.3 0.1 2.5 2 0 0 2 2 2 0 LIM domain zf-C2H2_4 PF13894.6 CEP14833.1 - 1.7 9.7 5.9 1.8 9.6 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Cwf_Cwc_15 PF04889.12 CEP14834.1 - 6.2e-80 268.5 28.2 7.1e-80 268.3 28.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.11 CEP14834.1 - 0.14 11.5 25.1 0.18 11.1 25.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 CEP14834.1 - 0.16 10.1 27.3 0.18 10.0 27.3 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CEP14834.1 - 4.9 5.8 12.5 6.5 5.4 12.5 1.4 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 CEP14834.1 - 9.6 5.1 9.2 12 4.7 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Aminotran_1_2 PF00155.21 CEP14835.1 - 1.1e-61 209.1 0.0 1.3e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP14835.1 - 0.0058 15.2 0.0 0.024 13.2 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEP14835.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Alliinase_C PF04864.13 CEP14835.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Allinase p450 PF00067.22 CEP14836.1 - 1.7e-72 244.7 0.0 2.1e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FliT PF05400.13 CEP14838.1 - 0.097 13.5 0.1 0.16 12.8 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliT RT_RNaseH_2 PF17919.1 CEP14839.1 - 1.9e-33 114.5 0.1 3.7e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP14839.1 - 1.5e-32 112.0 0.0 3.8e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP14839.1 - 3.4e-08 33.5 0.2 8.4e-08 32.2 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP14839.1 - 4.1e-08 33.4 0.0 9.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP14839.1 - 8.7e-05 22.7 0.1 0.00025 21.2 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger Peptidase_A17 PF05380.13 CEP14839.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Pao retrotransposon peptidase Integrase_Zn PF02022.19 CEP14839.1 - 0.032 14.2 1.0 0.53 10.3 0.1 2.5 2 0 0 2 2 2 0 Integrase Zinc binding domain DUF4065 PF13274.6 CEP14839.1 - 0.064 14.2 0.2 0.19 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) SMYLE_N PF18615.1 CEP14840.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hydant_A_N PF05378.13 CEP14841.1 - 0.005 16.6 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region zf-C2H2_jaz PF12171.8 CEP14844.1 - 0.066 13.5 2.5 0.11 12.8 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_65m PF03632.15 CEP14844.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain zf-C2H2_4 PF13894.6 CEP14844.1 - 1.8 9.6 5.3 0.42 11.6 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger CAP_GLY PF01302.25 CEP14847.1 - 4.4e-25 87.5 0.4 6.7e-25 86.9 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain CFTR_R PF14396.6 CEP14847.1 - 0.055 13.0 8.5 0.23 11.0 3.1 3.0 1 1 2 3 3 3 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain GREB1 PF15782.5 CEP14847.1 - 0.27 8.3 10.9 0.34 8.0 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 1-cysPrx_C PF10417.9 CEP14847.1 - 1.1 9.2 4.1 50 3.8 0.1 3.9 2 1 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Kinesin PF00225.23 CEP14848.1 - 1.8e-109 365.7 0.3 1.8e-109 365.7 0.3 2.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP14848.1 - 8.8e-29 100.4 2.4 1.4e-28 99.8 0.1 2.6 2 0 0 2 2 2 1 Microtubule binding HOOK PF05622.12 CEP14848.1 - 0.99 7.5 86.5 1.6 6.8 86.5 1.3 1 0 0 1 1 1 0 HOOK protein WD40 PF00400.32 CEP14849.1 - 2.4e-16 59.8 1.8 1.4e-05 25.8 0.3 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CEP14849.1 - 2.9e-09 36.4 12.4 2.9e-09 36.4 12.4 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 CEP14849.1 - 2.5e-05 24.5 0.2 0.11 12.8 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 CEP14849.1 - 0.0029 17.8 4.4 0.0029 17.8 4.4 2.7 1 1 1 2 2 2 1 Zinc-ribbon like family Rep_fac-A_C PF08646.10 CEP14849.1 - 0.076 12.8 3.9 0.24 11.2 3.9 1.8 1 0 0 1 1 1 0 Replication factor-A C terminal domain Paf1 PF03985.13 CEP14849.1 - 0.21 10.6 14.1 0.29 10.1 14.1 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 CEP14849.1 - 0.28 10.6 17.4 0.48 9.8 17.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CEP14849.1 - 0.39 8.9 18.1 0.55 8.4 18.1 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 CEP14849.1 - 0.46 10.3 8.1 0.9 9.4 8.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.12 CEP14849.1 - 0.75 8.7 12.9 1.2 8.1 12.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Cytomega_UL84 PF06284.11 CEP14849.1 - 7.6 4.9 6.2 12 4.2 6.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein HEAT_2 PF13646.6 CEP14850.1 - 3.8e-35 120.2 3.8 5.9e-14 52.2 0.1 4.4 3 2 2 5 5 4 4 HEAT repeats HEAT_PBS PF03130.16 CEP14850.1 - 1e-26 90.8 0.2 0.00018 21.9 0.0 7.0 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 CEP14850.1 - 5.1e-12 45.0 0.7 0.11 12.8 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat GIT_SHD PF08518.11 CEP14850.1 - 1.3e-08 34.3 1.2 2.7e-08 33.3 1.2 1.5 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT HEAT_EZ PF13513.6 CEP14850.1 - 0.0016 18.9 2.0 1.1 9.8 0.1 4.7 3 1 1 4 4 4 1 HEAT-like repeat GIT1_C PF12205.8 CEP14850.1 - 0.0044 17.1 0.5 0.0044 17.1 0.5 3.3 3 1 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term PAP_central PF04928.17 CEP14850.1 - 0.018 14.0 0.9 0.062 12.3 0.1 2.2 1 1 1 2 2 2 0 Poly(A) polymerase central domain APG6_N PF17675.1 CEP14850.1 - 0.025 15.1 25.2 0.088 13.3 25.2 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region Cohesin_HEAT PF12765.7 CEP14850.1 - 0.097 13.0 0.0 1.3 9.4 0.0 3.0 3 0 0 3 3 2 0 HEAT repeat associated with sister chromatid cohesion Spc7 PF08317.11 CEP14850.1 - 0.67 8.8 25.3 1.4 7.8 25.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CEP14850.1 - 0.9 9.0 12.6 2.9 7.4 12.6 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CEP14850.1 - 1.4 6.7 14.4 2.2 6.1 14.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF438 PF04282.13 CEP14850.1 - 3.8 7.5 13.5 33 4.5 0.0 5.2 5 0 0 5 5 5 0 Family of unknown function (DUF438) DUF724 PF05266.14 CEP14850.1 - 7.2 6.4 21.7 1.5 8.7 16.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YtxH PF12732.7 CEP14850.1 - 9.3 6.9 9.2 37 5.0 7.5 3.0 2 1 0 2 2 1 0 YtxH-like protein TraF PF13728.6 CEP14851.1 - 0.016 15.0 1.4 0.017 14.9 0.4 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein PROCN PF08083.11 CEP14852.1 - 5.3e-234 776.3 6.7 1.1e-233 775.3 6.7 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CEP14852.1 - 5.9e-129 428.5 0.2 1e-128 427.7 0.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 CEP14852.1 - 7.9e-88 292.1 3.8 2.4e-87 290.5 3.8 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 CEP14852.1 - 2.9e-85 284.1 2.9 2.9e-85 284.1 2.9 2.3 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 CEP14852.1 - 2.3e-73 244.6 0.0 4.5e-73 243.6 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CEP14852.1 - 2.5e-47 159.8 0.0 5.9e-47 158.6 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CEP14852.1 - 2.9e-45 152.5 0.4 7.8e-45 151.1 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CEP14852.1 - 1e-07 32.0 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Matrilin_ccoil PF10393.9 CEP14853.1 - 0.04 13.8 0.4 0.6 10.0 0.1 2.5 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin_1 PF12718.7 CEP14857.1 - 8.5e-29 100.5 48.4 4e-20 72.4 31.6 2.7 1 1 2 3 3 3 2 Tropomyosin like Tropomyosin PF00261.20 CEP14857.1 - 2.3e-07 30.4 41.9 0.0011 18.4 19.8 2.7 1 1 1 2 2 2 2 Tropomyosin bZIP_1 PF00170.21 CEP14857.1 - 5.9e-06 26.3 38.2 0.011 15.8 3.2 5.2 2 1 3 5 5 5 3 bZIP transcription factor GAS PF13851.6 CEP14857.1 - 7.5e-06 25.4 47.6 2.1e-05 23.9 34.1 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CEP14857.1 - 2.1e-05 24.9 46.5 0.0012 19.1 27.0 2.6 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CEP14857.1 - 0.00033 21.2 41.8 0.00051 20.6 12.7 2.6 1 1 1 2 2 2 2 Fez1 CENP-F_leu_zip PF10473.9 CEP14857.1 - 0.00045 20.2 48.2 0.022 14.8 26.3 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 CEP14857.1 - 0.0006 19.5 47.9 0.91 9.2 28.4 3.0 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.15 CEP14857.1 - 0.00095 19.2 43.8 0.87 9.7 8.9 5.5 2 1 3 5 5 5 3 Basic region leucine zipper SlyX PF04102.12 CEP14857.1 - 0.00099 19.7 46.6 0.016 15.8 4.1 4.9 2 1 3 5 5 5 2 SlyX Cnn_1N PF07989.11 CEP14857.1 - 0.0012 19.0 45.0 0.37 11.0 15.8 4.3 1 1 2 3 3 3 2 Centrosomin N-terminal motif 1 THOC7 PF05615.13 CEP14857.1 - 0.0044 17.3 12.2 0.0044 17.3 12.2 3.5 1 1 1 3 3 3 1 Tho complex subunit 7 TMF_DNA_bd PF12329.8 CEP14857.1 - 0.0049 16.8 51.8 0.077 13.0 12.1 4.2 1 1 3 4 4 4 2 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 CEP14857.1 - 0.0064 16.8 46.1 0.16 12.3 13.6 3.2 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 CEP14857.1 - 0.0099 16.4 53.6 3.2 8.3 27.5 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF724 PF05266.14 CEP14857.1 - 0.014 15.2 36.8 0.2 11.4 9.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 CEP14857.1 - 0.021 14.9 47.9 1.2 9.2 4.8 3.5 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5320 PF17253.2 CEP14857.1 - 0.033 15.3 31.8 0.13 13.4 2.8 4.2 2 1 3 5 5 5 0 Family of unknown function (DUF5320) DHR10 PF18595.1 CEP14857.1 - 0.038 14.0 52.7 0.41 10.7 15.2 3.5 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 CEP14857.1 - 0.057 12.3 48.2 0.18 10.6 11.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 CEP14857.1 - 0.067 13.0 52.9 0.63 9.8 4.9 5.2 2 1 3 5 5 5 0 Septum formation initiator RPW8 PF05659.11 CEP14857.1 - 0.083 12.6 19.2 1.2 8.8 10.8 3.7 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 ERM PF00769.19 CEP14857.1 - 0.1 12.4 47.2 0.46 10.3 27.9 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 CEP14857.1 - 0.13 12.6 37.1 0.2 12.1 3.2 5.9 1 1 5 6 6 6 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 CEP14857.1 - 0.21 12.5 44.3 0.063 14.2 17.8 3.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain SCO1-SenC PF02630.14 CEP14857.1 - 0.23 11.4 1.8 0.55 10.1 0.1 2.3 1 1 1 2 2 2 0 SCO1/SenC IFT57 PF10498.9 CEP14857.1 - 0.23 10.4 38.5 0.29 10.1 10.3 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3584 PF12128.8 CEP14857.1 - 0.24 8.9 43.0 0.27 8.7 43.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 CEP14857.1 - 0.29 11.6 59.4 0.47 10.9 3.2 4.8 1 1 3 4 4 4 0 Cell division protein ZapB Laminin_II PF06009.12 CEP14857.1 - 0.31 11.0 32.1 0.89 9.6 13.8 2.8 1 1 2 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.12 CEP14857.1 - 0.32 11.0 52.4 0.25 11.4 12.4 3.6 1 1 2 3 3 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 CEP14857.1 - 0.35 10.3 44.2 0.37 10.2 30.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Taxilin PF09728.9 CEP14857.1 - 0.37 9.9 43.0 1.2 8.2 11.7 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Filament PF00038.21 CEP14857.1 - 0.43 10.1 41.4 2.1 7.8 25.8 2.4 1 1 1 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 CEP14857.1 - 0.46 10.8 38.4 2.3 8.6 9.6 4.4 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Leu_zip PF15294.6 CEP14857.1 - 0.47 9.9 38.9 0.58 9.6 27.7 2.1 1 1 1 2 2 2 0 Leucine zipper Phage_GP20 PF06810.11 CEP14857.1 - 0.52 10.1 43.1 1.5 8.6 20.2 4.4 1 1 3 4 4 4 0 Phage minor structural protein GP20 KASH_CCD PF14662.6 CEP14857.1 - 0.56 10.0 49.8 0.27 11.1 27.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Atg14 PF10186.9 CEP14857.1 - 0.56 9.2 40.3 0.96 8.5 18.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 CEP14857.1 - 0.61 10.7 46.3 2.7 8.6 6.2 3.8 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 CEP14857.1 - 0.68 9.1 34.6 0.038 13.3 8.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF3450 PF11932.8 CEP14857.1 - 0.73 9.1 47.0 2.1 7.6 9.4 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HOOK PF05622.12 CEP14857.1 - 0.76 7.9 44.2 0.86 7.7 44.2 1.0 1 0 0 1 1 1 0 HOOK protein DUF2353 PF09789.9 CEP14857.1 - 0.84 8.9 38.9 8.3 5.7 38.9 2.2 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Jnk-SapK_ap_N PF09744.9 CEP14857.1 - 0.95 9.7 47.1 0.27 11.4 22.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 CEP14857.1 - 1.2 8.0 48.1 3.7 6.3 10.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF812) BRE1 PF08647.11 CEP14857.1 - 1.2 9.2 47.9 0.51 10.4 15.0 3.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase MbeD_MobD PF04899.12 CEP14857.1 - 1.8 8.7 27.3 0.63 10.2 7.6 3.5 2 1 0 3 3 3 0 MbeD/MobD like DUF4200 PF13863.6 CEP14857.1 - 1.8 9.0 50.3 2.8 8.4 19.9 3.1 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) Fmp27_SW PF10305.9 CEP14857.1 - 2.1 9.1 12.1 3.7 8.3 0.8 2.7 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain TMF_TATA_bd PF12325.8 CEP14857.1 - 2.3 8.5 41.0 1.2 9.4 11.8 3.3 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding DUF1657 PF07870.11 CEP14857.1 - 2.4 8.1 16.7 0.42 10.5 2.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) TolA_bind_tri PF16331.5 CEP14857.1 - 2.5 8.3 50.9 1.6 8.9 5.1 5.0 1 1 4 5 5 5 0 TolA binding protein trimerisation BST2 PF16716.5 CEP14857.1 - 2.5 8.7 47.7 0.78 10.4 11.1 3.8 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 CEP14857.1 - 2.7 8.0 30.9 3.3 7.7 3.3 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) SOGA PF11365.8 CEP14857.1 - 3.2 8.9 32.2 11 7.2 13.3 4.1 1 1 3 4 4 4 0 Protein SOGA Seryl_tRNA_N PF02403.22 CEP14857.1 - 3.3 8.0 42.0 13 6.0 5.8 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 CEP14857.1 - 3.3 7.9 38.0 0.99 9.6 19.2 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Cytokin-bind PF09265.10 CEP14857.1 - 3.3 7.0 12.4 0.45 9.9 3.4 2.1 1 1 1 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MAD PF05557.13 CEP14857.1 - 4 5.7 48.4 2.8 6.2 23.2 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Mt_ATP-synt_D PF05873.12 CEP14857.1 - 4.3 7.2 19.2 1.3 8.8 11.8 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) zf-C4H2 PF10146.9 CEP14857.1 - 5.4 7.3 37.0 14 5.9 9.3 2.8 1 1 1 2 2 2 0 Zinc finger-containing protein Med9 PF07544.13 CEP14857.1 - 5.9 7.0 39.7 0.93 9.6 3.1 3.7 1 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PI3K_P85_iSH2 PF16454.5 CEP14857.1 - 6 6.5 40.1 4.1 7.0 8.0 3.4 1 1 1 2 2 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CorA PF01544.18 CEP14857.1 - 6.3 6.0 26.6 1.4 8.2 14.6 2.4 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1640 PF07798.11 CEP14857.1 - 7.3 6.6 40.8 7.6 6.5 8.3 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) KLRAQ PF10205.9 CEP14857.1 - 7.6 6.8 40.7 14 6.0 8.9 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 CEP14857.1 - 8.4 5.6 35.9 2.9e+02 0.6 35.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_TACC PF12709.7 CEP14857.1 - 8.8 6.9 38.3 5.7 7.5 3.2 5.1 1 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1746 PF08508.10 CEP14858.1 - 0.027 14.8 0.4 0.09 13.1 0.4 1.8 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1746) ABC_membrane PF00664.23 CEP14859.1 - 2.1e-114 381.8 28.0 2e-59 201.5 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP14859.1 - 1.1e-67 226.8 0.3 2.4e-35 122.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP14859.1 - 2.6e-11 43.4 7.9 3.8e-05 23.2 0.0 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CEP14859.1 - 3.4e-10 40.6 0.9 0.00096 19.6 0.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CEP14859.1 - 1.6e-08 33.8 3.0 0.0014 17.5 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CEP14859.1 - 2.5e-08 34.3 3.1 0.0029 17.9 0.0 4.2 3 2 0 3 3 3 2 AAA domain G-alpha PF00503.20 CEP14859.1 - 1.5e-07 30.9 0.2 0.0022 17.2 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 CEP14859.1 - 3.9e-07 29.7 0.3 0.016 15.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 CEP14859.1 - 6e-06 26.7 3.9 0.11 12.9 1.2 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CEP14859.1 - 8.8e-06 25.7 0.1 0.039 13.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 CEP14859.1 - 1e-05 24.9 0.1 0.22 10.8 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 CEP14859.1 - 1.8e-05 24.6 0.6 0.078 12.7 0.1 3.6 2 2 0 2 2 2 2 AAA domain DUF815 PF05673.13 CEP14859.1 - 0.00014 21.1 0.1 0.1 11.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CEP14859.1 - 0.00015 21.7 0.1 1.6 8.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEP14859.1 - 0.00063 19.9 0.0 0.42 10.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 CEP14859.1 - 0.0016 18.0 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region APS_kinase PF01583.20 CEP14859.1 - 0.002 18.0 0.2 0.13 12.2 0.0 2.9 2 0 0 2 2 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.23 CEP14859.1 - 0.0031 17.6 0.3 1.9 8.6 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CEP14859.1 - 0.0046 17.5 0.0 1.3 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CEP14859.1 - 0.0056 16.8 1.5 2.1 8.4 0.1 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain SbcCD_C PF13558.6 CEP14859.1 - 0.0062 16.8 2.1 7.8 6.8 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CEP14859.1 - 0.0072 15.5 0.5 0.18 11.0 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain SRP54 PF00448.22 CEP14859.1 - 0.0083 15.8 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ECH_2 PF16113.5 CEP14859.1 - 0.009 15.5 0.1 0.69 9.3 0.0 2.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase AAA_15 PF13175.6 CEP14859.1 - 0.0092 15.7 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CEP14859.1 - 0.014 15.8 0.0 8.3 6.9 0.0 3.5 3 0 0 3 3 2 0 RNA helicase AAA_21 PF13304.6 CEP14859.1 - 0.015 15.1 0.9 0.68 9.7 0.0 3.1 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CEP14859.1 - 0.018 14.8 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEP14859.1 - 0.018 15.3 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEP14859.1 - 0.037 14.0 0.3 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CEP14859.1 - 0.04 13.5 0.1 10 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 CEP14859.1 - 0.046 13.0 0.4 3.9 6.7 0.0 2.7 2 1 0 2 2 2 0 Septin Rad17 PF03215.15 CEP14859.1 - 0.065 13.1 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CEP14859.1 - 0.069 12.5 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 CEP14859.1 - 0.086 12.6 0.1 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Synapsin_N PF10581.9 CEP14859.1 - 0.092 12.7 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Synapsin N-terminal DUF5450 PF17529.2 CEP14859.1 - 0.14 12.3 0.0 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5450) AAA_23 PF13476.6 CEP14859.1 - 0.15 12.5 0.7 4.8 7.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEP14859.1 - 0.3 10.8 3.3 43 3.8 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CEP14859.1 - 0.59 10.0 2.0 52 3.7 0.0 3.8 4 0 0 4 4 4 0 NTPase IKI3 PF04762.12 CEP14860.1 - 6.7e-276 918.0 0.0 1e-275 917.3 0.0 1.3 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CEP14860.1 - 0.0026 18.0 0.2 43 4.5 0.0 5.5 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP14860.1 - 0.0043 17.8 0.0 10 7.2 0.0 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Frtz PF11768.8 CEP14860.1 - 0.014 13.7 0.2 0.079 11.3 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PRKG1_interact PF15898.5 CEP14860.1 - 0.71 10.8 3.8 3.1 8.7 0.9 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Proteasome PF00227.26 CEP14861.1 - 3.8e-17 62.4 0.2 2.7e-08 33.5 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Epiglycanin_TR PF05647.11 CEP14862.1 - 0.11 12.4 8.4 0.15 12.0 8.4 1.1 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Aa_trans PF01490.18 CEP14863.1 - 3e-61 207.4 25.4 4e-61 206.9 25.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CEP14863.1 - 0.00046 19.3 21.2 0.0062 15.6 9.2 3.2 3 0 0 3 3 3 3 Tryptophan/tyrosine permease family MitMem_reg PF13012.6 CEP14864.1 - 1.9e-33 115.2 0.1 3.6e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEP14864.1 - 1.1e-14 54.4 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fungal_trans PF04082.18 CEP14865.1 - 2.3e-33 115.4 1.1 8e-33 113.6 0.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP14865.1 - 4e-08 33.3 12.5 7.2e-08 32.4 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM171 PF15471.6 CEP14866.1 - 0.0046 16.0 0.4 0.0046 16.0 0.4 1.6 1 1 0 2 2 2 1 Transmembrane protein family 171 Syndecan PF01034.20 CEP14866.1 - 0.22 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain AA_kinase PF00696.28 CEP14867.1 - 1.7e-40 139.1 0.1 2.5e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CEP14867.1 - 6.5e-12 45.0 0.7 6.9e-06 25.7 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 CEP14867.1 - 1.8e-10 40.4 3.2 2.4e-07 30.4 1.1 2.7 2 0 0 2 2 2 2 ACT domain DUF334 PF03904.13 CEP14867.1 - 0.011 15.2 0.3 0.018 14.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) FIST PF08495.10 CEP14868.1 - 7.1e-10 39.2 0.0 9.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 FIST N domain Endopep_inhib PF16800.5 CEP14868.1 - 0.094 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor ATP-gua_PtransN PF02807.15 CEP14868.1 - 0.16 12.4 0.1 0.46 10.9 0.1 1.8 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain FIST_C PF10442.9 CEP14868.1 - 0.17 11.8 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 FIST C domain DEAD PF00270.29 CEP14869.1 - 9.9e-44 149.2 0.0 2.1e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP14869.1 - 9.5e-22 77.4 0.1 4.8e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEP14869.1 - 1.4e-17 63.7 0.2 2.9e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEP14869.1 - 5.8e-07 29.7 0.0 5.8e-07 29.7 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 CEP14869.1 - 0.0022 17.8 4.2 0.0022 17.8 4.2 1.8 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein AAA_22 PF13401.6 CEP14869.1 - 0.0066 16.7 0.1 0.032 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain FWWh PF14922.6 CEP14869.1 - 0.036 14.0 0.2 0.082 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2358 PF10184.9 CEP14870.1 - 0.0015 18.8 0.0 0.027 14.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 CEP14870.1 - 0.04 13.1 0.9 0.15 11.2 0.9 1.8 1 1 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SnoaL PF07366.12 CEP14870.1 - 0.062 13.1 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF3472 PF11958.8 CEP14871.1 - 7.2e-28 98.2 5.6 1.2e-27 97.5 5.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 CEP14871.1 - 4.4e-11 43.0 0.1 9.8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) BNR PF02012.20 CEP14871.1 - 0.00089 18.9 0.4 0.0037 17.0 0.4 2.2 1 0 0 1 1 1 1 BNR/Asp-box repeat Pkinase PF00069.25 CEP14872.1 - 3.9e-69 232.9 0.0 4.8e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14872.1 - 2e-33 115.8 0.0 2.7e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP14872.1 - 4e-07 29.6 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CEP14872.1 - 1.4e-06 28.9 0.2 7.4e-06 26.6 0.5 2.1 2 1 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 CEP14872.1 - 8.7e-06 25.5 0.0 0.056 13.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CEP14872.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP14872.1 - 0.06 12.1 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_S14 PF00253.21 CEP14872.1 - 0.13 12.1 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Transketolase_N PF00456.21 CEP14873.1 - 1.5e-158 527.1 0.1 1.9e-158 526.8 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CEP14873.1 - 9.1e-45 152.5 0.0 1.5e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEP14873.1 - 1.6e-11 44.1 0.5 2.9e-10 40.1 0.1 2.6 2 1 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CEP14873.1 - 5.3e-05 22.6 0.0 0.00016 21.0 0.0 1.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CEP14873.1 - 0.0076 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Alba PF01918.21 CEP14873.1 - 0.067 13.0 1.8 0.14 12.0 0.2 2.4 2 0 0 2 2 2 0 Alba Terpene_synth PF01397.21 CEP14873.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Beta_elim_lyase PF01212.21 CEP14873.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase CBP_BcsR PF10945.8 CEP14873.1 - 0.2 11.2 0.2 0.37 10.3 0.2 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Peptidase_S48 PF03574.15 CEP14873.1 - 0.2 11.9 0.0 0.62 10.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S48 F5_F8_type_C PF00754.25 CEP14874.1 - 0.016 15.4 0.0 0.053 13.6 0.0 1.9 1 0 0 1 1 1 0 F5/8 type C domain Aa_trans PF01490.18 CEP14875.1 - 4.4e-54 183.8 36.3 3.2e-53 180.9 36.3 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GATA PF00320.27 CEP14876.1 - 1.1e-16 60.1 2.7 2.1e-16 59.2 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CEP14876.1 - 1.3e-13 50.5 0.4 2.7e-13 49.5 0.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF913 PF06025.12 CEP14877.1 - 0.013 14.6 0.4 0.04 12.9 0.4 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4611 PF15387.6 CEP14877.1 - 1.9 8.8 7.0 0.93 9.8 2.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Amidohydro_1 PF01979.20 CEP14878.1 - 4.3e-67 226.9 0.0 5.2e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP14878.1 - 1e-06 28.5 0.1 0.0078 15.7 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family SMG1 PF15785.5 CEP14878.1 - 0.021 13.2 0.0 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Conotoxin PF02950.17 CEP14879.1 - 0.27 12.3 0.0 0.27 12.3 0.0 3.0 3 0 0 3 3 3 0 Conotoxin PS_Dcarbxylase PF02666.15 CEP14881.1 - 6.9e-72 241.2 0.0 2.6e-70 236.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 CEP14881.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 MNLL subunit DNA_pol_E_B PF04042.16 CEP14882.1 - 1.7e-45 155.0 0.1 2.6e-45 154.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CEP14882.1 - 1.5e-36 125.4 0.0 2.7e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Phosphodiest PF01663.22 CEP14883.1 - 1.1e-85 288.4 1.4 1.3e-85 288.2 1.4 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CEP14883.1 - 4.1e-06 26.4 0.6 0.0012 18.3 0.1 2.6 1 1 0 2 2 2 2 Sulfatase PglZ PF08665.12 CEP14883.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 PglZ domain BTB PF00651.31 CEP14884.1 - 8.7e-18 64.6 0.2 1.5e-16 60.6 0.0 2.7 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 CEP14884.1 - 3.8e-09 36.6 0.0 0.00038 20.5 0.0 2.8 3 0 0 3 3 3 2 BTB And C-terminal Kelch PAC1 PF16094.5 CEP14884.1 - 0.11 11.7 3.2 0.95 8.6 1.9 2.3 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Myc_N PF01056.18 CEP14884.1 - 0.35 10.7 4.9 0.58 10.0 4.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.6 CEP14884.1 - 3 8.1 7.2 3.9 7.7 5.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Ribosomal_60s PF00428.19 CEP14884.1 - 7.4 7.2 13.4 33 5.1 7.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Na_Ca_ex PF01699.24 CEP14885.1 - 4.3e-39 133.9 39.7 1.8e-20 73.5 9.3 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MOZ_SAS PF01853.18 CEP14886.1 - 5.3e-81 270.6 0.3 9.1e-81 269.8 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEP14886.1 - 2.3e-20 72.0 2.9 2.3e-20 72.0 2.9 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CEP14886.1 - 0.00095 19.5 0.0 0.0027 18.1 0.0 1.8 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain DUF4685 PF15737.5 CEP14886.1 - 0.22 12.0 7.0 0.51 10.8 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) GREB1 PF15782.5 CEP14886.1 - 0.34 8.0 4.6 0.45 7.6 4.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CEP14886.1 - 0.6 8.6 5.7 0.87 8.1 5.7 1.2 1 0 0 1 1 1 0 Macoilin family CHZ PF09649.10 CEP14886.1 - 0.62 9.6 3.8 1.8 8.1 3.8 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF5364 PF17322.2 CEP14886.1 - 2.9 8.1 6.9 1.8 8.9 4.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5364) CCDC106 PF15794.5 CEP14886.1 - 3.2 7.4 16.4 3 7.5 7.7 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 IMUP PF15761.5 CEP14886.1 - 7.5 7.3 13.9 9.7 6.9 10.7 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4692 PF15763.5 CEP14886.1 - 7.6 7.0 9.6 31 5.0 9.9 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SesA PF17107.5 CEP14887.1 - 0.044 14.0 0.4 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF592 PF04574.13 CEP14887.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) SpecificRecomb PF10136.9 CEP14887.1 - 0.093 11.0 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 Site-specific recombinase HTH_23 PF13384.6 CEP14887.1 - 0.15 11.9 0.8 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Phosphoprotein PF00922.17 CEP14888.1 - 0.024 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Aldo_ket_red PF00248.21 CEP14889.1 - 5.4e-58 196.5 0.0 6.5e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nucleo_P87 PF07267.11 CEP14890.1 - 0.0084 15.0 1.5 0.011 14.6 1.5 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 HNOBA PF07701.14 CEP14890.1 - 0.041 13.3 0.1 0.052 13.0 0.1 1.1 1 0 0 1 1 1 0 Heme NO binding associated FAM176 PF14851.6 CEP14890.1 - 0.33 10.6 2.9 0.49 10.0 2.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF2076 PF09849.9 CEP14890.1 - 1.8 8.5 8.8 2.6 8.0 8.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 CEP14890.1 - 2.5 7.3 8.8 3.4 6.9 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein HMG_box PF00505.19 CEP14891.1 - 2.1e-19 69.7 2.5 4.7e-19 68.6 2.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP14891.1 - 2e-08 34.7 0.9 2e-08 34.7 0.9 2.4 2 0 0 2 2 2 1 HMG-box domain BCS1_N PF08740.11 CEP14891.1 - 0.018 15.0 1.6 0.026 14.5 1.6 1.3 1 0 0 1 1 1 0 BCS1 N terminal Pribosyltran PF00156.27 CEP14892.1 - 8.7e-22 77.3 0.0 1.1e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ERF PF04404.12 CEP14892.1 - 0.044 13.6 0.1 0.068 13.0 0.1 1.2 1 0 0 1 1 1 0 ERF superfamily PRTase_2 PF15609.6 CEP14892.1 - 0.054 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Lectin_C PF00059.21 CEP14893.1 - 0.026 15.3 0.1 0.24 12.1 0.1 2.2 1 1 1 2 2 2 0 Lectin C-type domain RhoGEF PF00621.20 CEP14894.1 - 3.3e-07 30.7 0.7 9.6e-07 29.2 0.7 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CEP14894.1 - 0.00011 22.6 2.1 0.011 16.2 0.0 3.0 3 0 0 3 3 3 2 PH domain Ran_BP1 PF00638.18 CEP14894.1 - 0.027 14.7 2.3 0.68 10.2 1.0 2.5 2 0 0 2 2 2 0 RanBP1 domain CENP-B_dimeris PF09026.10 CEP14894.1 - 0.99 9.8 5.8 2.5 8.6 5.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Chromo PF00385.24 CEP14895.1 - 9.9e-07 28.6 0.7 2.5e-06 27.3 0.2 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MLVIN_C PF18697.1 CEP14895.1 - 0.047 13.8 0.2 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain FMO-like PF00743.19 CEP14896.1 - 5.7e-24 84.4 0.1 1.8e-23 82.8 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CEP14896.1 - 2e-11 43.9 0.0 4.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEP14896.1 - 7.5e-07 28.6 0.1 9.4e-06 25.0 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEP14896.1 - 1.5e-05 24.4 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP14896.1 - 2.2e-05 24.2 0.0 0.00071 19.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP14896.1 - 0.0041 16.4 0.7 4.5 6.4 1.2 3.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP14896.1 - 0.01 15.8 0.0 0.76 9.7 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 CEP14896.1 - 0.045 13.0 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 CEP14896.1 - 0.12 11.5 0.2 9.4 5.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-H2C2_2 PF13465.6 CEP14897.1 - 9e-12 44.9 18.5 3.4e-06 27.2 5.0 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP14897.1 - 9e-11 41.6 9.8 5.4e-06 26.6 1.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP14897.1 - 8e-05 23.2 15.1 0.0043 17.8 1.0 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP14897.1 - 0.017 15.7 1.0 0.048 14.3 0.0 2.2 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEP14897.1 - 0.021 15.1 0.5 0.021 15.1 0.5 2.3 3 1 0 3 3 3 0 C2H2-type zinc ribbon DUF2225 PF09986.9 CEP14897.1 - 0.19 11.4 1.8 2.3 7.9 1.8 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.6 CEP14897.1 - 0.51 10.4 3.3 21 5.2 0.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger DUF1367 PF07105.11 CEP14898.1 - 0.0035 17.0 0.1 0.73 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1367) DUF397 PF04149.12 CEP14898.1 - 0.097 12.8 0.1 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF397) DUF4890 PF16231.5 CEP14898.1 - 0.099 13.1 0.0 1.3 9.5 0.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4890) TPK_catalytic PF04263.16 CEP14900.1 - 1.9e-36 124.7 0.1 5.9e-36 123.1 0.1 1.7 1 1 1 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CEP14900.1 - 1.6e-18 66.2 0.0 2.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain COG2 PF06148.11 CEP14900.1 - 0.12 12.4 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TINF2_N PF14973.6 CEP14900.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Cpn10 PF00166.21 CEP14901.1 - 1.5e-30 105.1 0.1 1.7e-30 104.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RhoGAP PF00620.27 CEP14902.1 - 7.6e-31 107.0 0.0 1.2e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.20 CEP14903.1 - 8.6e-29 101.1 0.2 1.9e-28 100.0 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP14903.1 - 2.7e-20 72.8 0.0 1e-19 70.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 CEP14903.1 - 1.2e-11 44.5 0.1 2.7e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LHH PF14411.6 CEP14903.1 - 0.058 13.6 1.1 11 6.2 0.2 2.7 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH EI24 PF07264.11 CEP14906.1 - 6.5e-20 72.1 10.8 9e-20 71.7 10.8 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SBF_like PF13593.6 CEP14906.1 - 0.003 16.9 0.9 0.003 16.9 0.9 1.7 2 0 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) DUF2079 PF09852.9 CEP14906.1 - 0.004 16.1 0.6 0.004 16.1 0.6 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2079) MFS_1 PF07690.16 CEP14906.1 - 0.014 14.4 7.7 0.024 13.6 7.7 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily MMPL PF03176.15 CEP14906.1 - 0.11 11.3 0.9 0.21 10.5 0.9 1.4 1 0 0 1 1 1 0 MMPL family Pkinase PF00069.25 CEP14907.1 - 4e-71 239.5 0.0 5.9e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14907.1 - 1e-34 120.0 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP14907.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP14907.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RGS PF00615.19 CEP14908.1 - 1.1e-08 35.3 0.0 5.1e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Metallophos PF00149.28 CEP14909.1 - 6.3e-09 36.6 2.1 6.3e-09 36.6 2.1 2.6 2 2 1 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP14909.1 - 1.9e-07 31.5 0.3 1.9e-06 28.2 0.1 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PC-Esterase PF13839.6 CEP14909.1 - 0.0001 22.2 0.0 0.0047 16.7 0.0 2.7 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 CEP14909.1 - 1.1 9.6 5.3 1.9 8.8 2.3 2.7 2 0 0 2 2 2 0 PMR5 N terminal Domain EF-hand_7 PF13499.6 CEP14910.1 - 2.5e-07 31.1 2.3 6.8e-07 29.6 2.3 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEP14910.1 - 3.1e-07 29.8 2.6 8.3e-07 28.5 0.5 2.7 2 2 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEP14910.1 - 0.00054 19.3 0.2 0.00054 19.3 0.2 3.5 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 CEP14910.1 - 0.009 15.5 4.4 0.036 13.6 0.0 3.3 3 1 1 4 4 4 1 EF hand Ribosomal_S3Ae PF01015.18 CEP14911.1 - 1.4e-84 282.7 6.0 1.6e-84 282.5 6.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF2187 PF09953.9 CEP14912.1 - 0.11 12.5 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) RyR PF02026.16 CEP14913.1 - 0.0079 16.4 4.8 0.052 13.8 0.9 3.0 3 1 0 3 3 3 1 RyR domain DUF1798 PF08807.10 CEP14913.1 - 0.39 10.9 4.1 1.5 9.0 0.8 2.6 2 1 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Androgen_recep PF02166.16 CEP14914.1 - 0.01 14.7 2.9 0.015 14.1 2.9 1.2 1 0 0 1 1 1 0 Androgen receptor GCV_H PF01597.19 CEP14914.1 - 0.044 13.7 0.2 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein ORC_WH_C PF18137.1 CEP14914.1 - 0.12 12.4 0.6 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF2967 PF11179.8 CEP14914.1 - 2 6.4 5.3 3.2 5.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) HMG_box PF00505.19 CEP14915.1 - 3e-16 59.6 0.1 3e-16 59.6 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP14915.1 - 1.5e-11 44.7 0.1 1.5e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 HMG-box domain BRE1 PF08647.11 CEP14915.1 - 1.6 8.9 7.7 0.07 13.2 1.8 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CTP_transf_like PF01467.26 CEP14916.1 - 2.7e-24 86.0 0.0 3.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Aminotran_1_2 PF00155.21 CEP14917.1 - 7.6e-59 199.7 0.0 9.1e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP14917.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 CEP14917.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 CEP14917.1 - 0.037 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEP14917.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CEP14917.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Methyltransf_32 PF13679.6 CEP14918.1 - 6.7e-30 104.2 0.0 1.1e-29 103.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP14918.1 - 0.00071 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP14918.1 - 0.0016 18.0 0.1 0.0036 16.9 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CEP14918.1 - 0.0024 17.7 0.1 0.0052 16.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP14918.1 - 0.0026 18.4 0.0 0.0076 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP14918.1 - 0.0038 17.9 0.0 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CEP14918.1 - 0.11 11.7 0.2 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ribosomal_L6 PF00347.23 CEP14919.1 - 5.9e-22 78.1 0.1 3.1e-09 37.4 0.0 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 Ank_2 PF12796.7 CEP14920.1 - 3.6e-63 210.1 20.7 1.2e-17 64.2 0.9 6.4 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP14920.1 - 7.4e-61 201.8 2.2 1.3e-15 57.5 0.1 7.0 4 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 CEP14920.1 - 2.4e-51 170.0 17.6 8.2e-08 32.4 0.1 9.7 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 CEP14920.1 - 5e-50 166.9 13.4 5.2e-11 42.6 0.0 7.8 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP14920.1 - 7e-46 148.9 1.0 1.7e-05 24.8 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat zf-C2H2_2 PF12756.7 CEP14921.1 - 5.7e-33 113.3 13.5 9e-23 80.5 3.5 3.3 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEP14921.1 - 5e-06 26.9 18.5 0.004 17.9 0.5 5.7 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.7 CEP14921.1 - 6.1e-06 26.5 12.7 0.00041 20.6 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP14921.1 - 1.8e-05 24.9 5.7 6e-05 23.2 1.4 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CEP14921.1 - 0.00064 20.0 1.4 0.00064 20.0 1.4 5.8 6 0 0 6 6 5 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CEP14921.1 - 0.0023 17.7 0.4 0.0023 17.7 0.4 3.5 4 1 0 4 4 4 1 zinc-finger C2H2-type PyrI_C PF02748.15 CEP14921.1 - 0.023 14.6 2.7 0.13 12.2 0.0 3.3 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CEP14921.1 - 0.025 14.6 0.3 0.025 14.6 0.3 4.2 5 0 0 5 5 5 0 BED zinc finger Clr5 PF14420.6 CEP14921.1 - 0.097 12.9 3.7 5.6 7.3 0.0 3.4 3 0 0 3 3 3 0 Clr5 domain FOXP-CC PF16159.5 CEP14921.1 - 0.23 12.1 10.4 6.6 7.4 0.0 5.4 5 0 0 5 5 5 0 FOXP coiled-coil domain Spc7_N PF15402.6 CEP14921.1 - 0.77 7.9 9.1 1.5 7.0 9.1 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-C2HE PF16278.5 CEP14921.1 - 1.7 9.1 11.0 3.5 8.2 0.3 3.3 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CEP14921.1 - 4.6 7.4 19.4 0.18 11.9 1.2 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Syntaxin_2 PF14523.6 CEP14922.1 - 1.1e-26 93.1 3.8 1.1e-26 93.1 3.8 2.7 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 CEP14922.1 - 1.1e-08 35.0 14.8 2.3e-08 33.9 14.7 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CEP14922.1 - 3.1e-07 30.3 2.0 1.2e-06 28.4 2.0 2.1 1 1 0 1 1 1 1 SNARE domain FUSC PF04632.12 CEP14922.1 - 0.0096 14.5 0.4 0.013 14.1 0.4 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family V-SNARE PF05008.15 CEP14922.1 - 0.048 14.1 1.5 0.048 14.1 1.5 3.2 3 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus CEP209_CC5 PF16574.5 CEP14922.1 - 0.056 13.6 9.1 0.17 12.1 9.1 1.9 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 LMBR1 PF04791.16 CEP14922.1 - 2 7.2 8.5 4.6 6.0 3.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Methyltransf_25 PF13649.6 CEP14923.1 - 5.4e-18 65.5 0.0 2e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP14923.1 - 5.9e-16 58.9 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP14923.1 - 3.8e-14 52.8 0.0 3.3e-13 49.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP14923.1 - 4.8e-14 52.5 0.0 6.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP14923.1 - 5.5e-08 33.5 0.0 1.6e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP14923.1 - 9.2e-08 31.7 0.0 3e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CEP14923.1 - 9.5e-06 25.2 0.0 0.00029 20.4 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 CEP14923.1 - 1.7e-05 24.3 0.1 5.9e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CEP14923.1 - 5.7e-05 22.5 0.0 7.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 CEP14923.1 - 6.6e-05 22.9 0.0 9.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 CEP14923.1 - 0.00052 20.2 0.0 0.0017 18.5 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase CheR PF01739.18 CEP14923.1 - 0.0097 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 CEP14923.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 CEP14923.1 - 0.042 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RabGAP-TBC PF00566.18 CEP14924.1 - 1.7e-15 57.3 2.6 9.2e-10 38.5 0.7 3.0 2 1 1 3 3 3 2 Rab-GTPase-TBC domain Pox_A30L_A26L PF06086.12 CEP14924.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Zn_clus PF00172.18 CEP14925.1 - 0.0012 18.9 18.5 0.0018 18.4 18.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 CEP14926.1 - 0.029 14.4 4.8 0.034 14.2 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 CEP14926.1 - 0.059 13.0 6.6 0.093 12.3 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2973 PF11189.8 CEP14927.1 - 0.11 12.6 0.8 9.1 6.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) DUF2371 PF10177.9 CEP14927.1 - 0.13 12.5 0.5 3.4 7.9 0.0 3.1 3 1 1 4 4 4 0 Uncharacterised conserved protein (DUF2371) Homeodomain PF00046.29 CEP14928.1 - 6.3e-17 61.2 1.5 1.4e-16 60.0 1.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP14928.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.4 2 0 0 2 2 2 0 Homeobox KN domain NAD_binding_1 PF00175.21 CEP14931.1 - 2.1e-33 115.2 0.0 3.7e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEP14931.1 - 3.5e-23 81.8 0.0 9e-23 80.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEP14931.1 - 5.2e-09 36.4 0.0 1.1e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEP14931.1 - 0.031 14.5 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Velvet PF11754.8 CEP14932.1 - 3.2e-48 164.8 12.3 2e-33 116.4 0.5 3.1 2 1 1 3 3 3 2 Velvet factor SRF-TF PF00319.18 CEP14933.1 - 3.3e-21 74.5 0.1 5.1e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.16 CEP14934.1 - 2.6e-23 82.5 43.7 4.4e-12 45.6 19.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP14934.1 - 1.3e-08 34.1 21.6 3.9e-08 32.6 6.9 2.9 1 1 0 2 2 2 2 Sugar (and other) transporter DUF2371 PF10177.9 CEP14934.1 - 0.18 11.9 0.6 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF4179 PF13786.6 CEP14934.1 - 2 9.0 4.8 4.9 7.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) OATP PF03137.20 CEP14934.1 - 3.1 6.0 19.5 0.15 10.3 2.2 4.2 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF3176 PF11374.8 CEP14934.1 - 3.6 7.8 10.8 0.28 11.4 3.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3176) DUF3712 PF12505.8 CEP14935.1 - 8.7e-72 239.3 27.1 3.9e-23 82.1 0.8 5.7 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CEP14935.1 - 7e-07 29.7 6.7 1.3 9.7 0.3 7.2 7 0 0 7 7 7 2 Late embryogenesis abundant protein Sigma_reg_N PF13800.6 CEP14935.1 - 0.0059 16.9 0.9 0.016 15.5 0.9 1.7 1 0 0 1 1 1 1 Sigma factor regulator N-terminal SP_C-Propep PF08999.10 CEP14935.1 - 0.021 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tmemb_9 PF05434.11 CEP14935.1 - 0.039 13.8 0.2 0.07 13.0 0.2 1.3 1 0 0 1 1 1 0 TMEM9 Chordopox_A13L PF05961.11 CEP14935.1 - 0.78 10.0 2.5 1.6 9.0 2.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Dynein_attach_N PF15867.5 CEP14936.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Dynein attachment factor N-terminus zf-RVT PF13966.6 CEP14937.1 - 1.7e-07 31.9 0.7 3.4e-07 30.9 0.7 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EI24 PF07264.11 CEP14938.1 - 6.5e-08 33.0 8.3 8e-06 26.2 1.6 2.2 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) CBM_14 PF01607.24 CEP14939.1 - 4.4e-07 30.0 0.2 5.6e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Pkinase PF00069.25 CEP14940.1 - 5.2e-46 157.1 0.0 2.3e-45 155.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14940.1 - 2.8e-23 82.5 0.0 4.1e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP14940.1 - 0.0024 17.2 0.0 0.0052 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP14940.1 - 0.018 14.9 0.1 1.4 8.8 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CEP14940.1 - 0.082 12.5 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEP14940.1 - 0.19 10.5 0.0 0.19 10.5 0.0 2.2 2 1 0 3 3 3 0 Fungal protein kinase ACBP PF00887.19 CEP14941.1 - 2.3e-25 88.6 0.1 1e-24 86.6 0.1 2.1 1 0 0 1 1 1 1 Acyl CoA binding protein DUF5117 PF17148.4 CEP14941.1 - 0.0014 18.5 0.3 0.0034 17.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5117) DUF4611 PF15387.6 CEP14941.1 - 0.011 15.9 3.2 0.011 15.9 3.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) AATF-Che1 PF13339.6 CEP14941.1 - 0.084 13.6 0.4 0.084 13.6 0.4 3.1 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor Cwf_Cwc_15 PF04889.12 CEP14941.1 - 1.5 8.5 17.9 0.57 9.9 2.5 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF974 PF06159.13 CEP14942.1 - 1.5e-77 260.7 0.1 2.7e-77 259.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF974) Trs65 PF12735.7 CEP14942.1 - 1.3e-09 38.0 0.4 1.8e-05 24.3 0.0 3.8 4 0 0 4 4 4 3 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 CEP14942.1 - 0.00037 20.6 0.1 0.026 14.6 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain DUF4449 PF14613.6 CEP14943.1 - 5.3e-12 46.1 0.7 5.3e-12 46.1 0.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 CEP14943.1 - 7.5e-05 22.4 0.1 0.00021 20.9 0.1 1.7 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain THP2 PF09432.10 CEP14943.1 - 0.078 13.0 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF2294 PF10057.9 CEP14943.1 - 0.24 11.6 2.1 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) CotH PF08757.11 CEP14944.1 - 2.5e-33 116.0 0.0 3.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 CotH kinase protein Iron_transport PF10634.9 CEP14944.1 - 0.05 13.8 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Fe2+ transport protein Pkinase PF00069.25 CEP14946.1 - 3.9e-60 203.5 0.0 6.3e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP14946.1 - 2.7e-45 154.7 0.0 5.6e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP14946.1 - 1.6e-05 23.9 0.0 1.6e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CEP14946.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PIEZO PF15917.5 CEP14946.1 - 2.1 7.7 5.0 6 6.3 5.0 1.7 1 0 0 1 1 1 0 Piezo YabA PF06156.13 CEP14946.1 - 2.6 8.7 5.4 8.3 7.1 5.4 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Peptidase_S8 PF00082.22 CEP14947.1 - 2.5e-47 161.6 2.5 3.6e-47 161.1 2.5 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CEP14947.1 - 1e-07 32.6 0.3 2.8e-07 31.2 0.3 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 CEP14947.1 - 7.6e-06 25.9 0.1 1.9e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 PA domain Motile_Sperm PF00635.26 CEP14947.1 - 0.0042 16.9 0.4 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 MSP (Major sperm protein) domain FixG_C PF11614.8 CEP14947.1 - 0.027 14.7 0.0 0.092 13.0 0.0 1.8 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Ribosomal_L24e PF01246.20 CEP14948.1 - 6e-26 90.5 0.1 6e-26 90.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e MMU163 PF17119.5 CEP14948.1 - 0.25 10.5 2.0 0.34 10.0 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Ribosomal_S4e PF00900.20 CEP14949.1 - 2.2e-38 130.0 1.0 3.4e-37 126.2 0.4 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CEP14949.1 - 6.3e-26 89.8 0.0 1.4e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CEP14949.1 - 4.2e-19 68.4 7.3 1.4e-18 66.7 7.8 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CEP14949.1 - 3.1e-07 30.0 0.0 8.8e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CEP14949.1 - 1.6e-05 24.7 8.1 6.1e-05 22.8 6.1 3.0 3 1 0 3 3 3 1 KOW motif HSF_DNA-bind PF00447.17 CEP14950.1 - 2.9e-32 111.1 2.3 2.9e-32 111.1 2.3 2.1 2 1 0 2 2 2 1 HSF-type DNA-binding zf-C4H2 PF10146.9 CEP14950.1 - 5.3 7.3 11.3 0.51 10.6 6.0 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein CAP_GLY PF01302.25 CEP14951.1 - 3.5e-19 68.6 0.1 5.5e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Dehydrin PF00257.19 CEP14951.1 - 0.013 16.1 2.3 0.013 16.1 2.3 2.4 2 0 0 2 2 2 0 Dehydrin Holin_BhlA PF10960.8 CEP14951.1 - 0.016 15.2 0.5 0.016 15.2 0.5 1.9 2 0 0 2 2 2 0 BhlA holin family Cse1 PF08506.10 CEP14952.1 - 5.5e-143 476.3 5.2 2e-142 474.4 4.1 2.0 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CEP14952.1 - 7.7e-124 413.6 0.2 1.5e-123 412.6 0.2 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus WD40 PF00400.32 CEP14952.1 - 1.3e-27 95.4 13.8 1.4e-05 25.8 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat IBN_N PF03810.19 CEP14952.1 - 2.1e-15 56.4 0.8 1e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain ANAPC4_WD40 PF12894.7 CEP14952.1 - 1.6e-14 54.0 0.0 6.2e-06 26.4 0.0 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP14952.1 - 1.9e-05 24.6 0.3 0.017 15.0 0.1 3.8 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP14952.1 - 0.00052 19.1 0.6 0.21 10.5 0.0 3.5 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CEP14952.1 - 0.0063 16.4 3.0 0.067 13.1 0.2 3.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 CEP14952.1 - 0.0066 16.3 0.7 0.016 15.0 0.7 1.7 1 0 0 1 1 1 1 HIRA B motif Xpo1 PF08389.12 CEP14952.1 - 0.034 14.2 2.6 1.2 9.2 0.1 3.9 2 2 2 4 4 4 0 Exportin 1-like protein F-box-like PF12937.7 CEP14953.1 - 3.7e-09 36.3 1.9 1.1e-08 34.9 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP14953.1 - 8.2e-05 22.4 1.7 9.2e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain Fungal_trans PF04082.18 CEP14954.1 - 2.1e-24 86.0 0.0 2.1e-24 86.0 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP14954.1 - 7.6e-11 42.0 12.4 2e-10 40.6 12.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.8 CEP14954.1 - 0.087 12.8 17.7 0.2 11.6 8.8 2.6 2 0 0 2 2 2 0 Velvet factor Presenilin PF01080.17 CEP14954.1 - 0.73 8.5 24.5 0.024 13.4 10.5 2.2 2 0 0 2 2 2 0 Presenilin HAUS6_N PF14661.6 CEP14954.1 - 0.92 9.0 19.1 0.027 14.1 12.3 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LMBR1 PF04791.16 CEP14954.1 - 1.2 7.9 6.5 2.2 7.1 6.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Pex14_N PF04695.13 CEP14954.1 - 2.7 8.6 40.6 1.9 9.1 6.8 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GREB1 PF15782.5 CEP14954.1 - 3.7 4.6 26.4 0.51 7.4 11.3 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Exonuc_VII_L PF02601.15 CEP14954.1 - 8.6 5.8 23.1 0.23 11.0 14.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Not1 PF04054.15 CEP14955.1 - 9.5e-142 472.3 6.5 9.5e-142 472.3 6.5 2.4 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CEP14955.1 - 2.8e-99 331.1 8.9 1.2e-97 325.8 4.9 2.8 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CEP14955.1 - 1.3e-68 229.9 0.2 5.7e-68 227.8 0.2 2.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CEP14955.1 - 2.1e-49 167.2 8.6 2.1e-49 167.2 8.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CEP14955.1 - 2.8e-22 79.4 2.7 8.9e-22 77.8 2.1 2.2 1 1 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DDE_3 PF13358.6 CEP14957.1 - 7.1e-28 97.2 0.0 1.4e-18 67.0 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 CEP14957.1 - 0.00038 20.7 0.1 0.00087 19.6 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP14957.1 - 0.0092 16.6 0.0 0.13 12.9 0.0 2.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 CEP14957.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 CEP14957.1 - 0.029 14.2 0.4 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DUF2203 PF09969.9 CEP14957.1 - 0.09 13.5 0.1 11 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SOXp PF12336.8 CEP14957.1 - 0.1 13.7 0.0 0.25 12.4 0.0 1.6 1 0 0 1 1 1 0 SOX transcription factor HTH_29 PF13551.6 CEP14957.1 - 0.17 11.9 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix ADH_N PF08240.12 CEP14959.1 - 1.7e-24 85.8 6.5 2.7e-24 85.1 6.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP14959.1 - 3.1e-17 62.8 0.0 5.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEP14959.1 - 5.5e-05 22.6 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CEP14959.1 - 9.5e-05 21.8 0.1 0.00019 20.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CEP14959.1 - 0.001 20.1 0.0 0.0017 19.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 CEP14959.1 - 0.0044 17.2 0.1 0.0067 16.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CEP14959.1 - 0.24 11.3 0.2 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FSH1 PF03959.13 CEP14960.1 - 5.2e-53 179.8 0.0 7.8e-52 176.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Vwaint PF14624.6 CEP14960.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 VWA / Hh protein intein-like DUF3319 PF11782.8 CEP14960.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) Abhydrolase_2 PF02230.16 CEP14960.1 - 0.23 11.2 1.4 4 7.2 1.4 2.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Zn_clus PF00172.18 CEP14961.1 - 9.6e-05 22.4 14.7 0.00016 21.7 14.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L16 PF00252.18 CEP14962.1 - 5e-46 156.0 0.8 6.3e-46 155.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cpn60_TCP1 PF00118.24 CEP14964.1 - 5.2e-155 516.8 6.6 5.9e-155 516.6 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 CEP14964.1 - 0.081 12.8 0.1 0.28 11.0 0.2 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein zf-C2H2 PF00096.26 CEP14965.1 - 1.1e-07 31.9 9.9 0.002 18.5 2.2 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP14965.1 - 1.6e-06 28.4 3.9 0.026 15.3 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP14965.1 - 0.0038 17.2 0.7 0.091 12.8 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP14965.1 - 0.011 16.1 2.6 0.011 16.1 2.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 CEP14965.1 - 0.059 13.3 0.2 0.059 13.3 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 CEP14965.1 - 0.082 13.0 1.2 1.8 8.8 0.1 2.7 2 1 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 CEP14965.1 - 0.48 10.2 7.6 0.11 12.3 0.6 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type PALP PF00291.25 CEP14966.1 - 4.9e-68 229.7 3.0 5.9e-68 229.4 3.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Toprim_3 PF13362.6 CEP14966.1 - 0.004 17.5 0.0 0.057 13.8 0.0 2.6 3 0 0 3 3 3 1 Toprim domain DUF3343 PF11823.8 CEP14966.1 - 0.14 11.7 0.0 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) KDZ PF18758.1 CEP14967.1 - 4e-23 82.2 0.5 7e-23 81.4 0.5 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-RING_11 PF17123.5 CEP14968.1 - 4.6e-05 23.1 0.9 0.00011 21.9 0.9 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEP14968.1 - 5.1e-05 23.2 0.4 0.00014 21.8 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEP14968.1 - 0.00038 20.7 2.4 0.00038 20.7 2.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP14968.1 - 0.00052 19.8 1.9 0.0016 18.2 1.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP14968.1 - 0.012 15.4 2.2 0.012 15.4 2.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FPP PF05911.11 CEP14968.1 - 0.019 13.2 43.3 0.029 12.6 43.3 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Prefoldin_2 PF01920.20 CEP14968.1 - 0.019 14.9 5.2 0.019 14.9 5.2 6.5 3 2 3 6 6 6 0 Prefoldin subunit UCR_hinge PF02320.16 CEP14968.1 - 0.19 12.0 8.7 0.24 11.6 0.8 3.4 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein ERM PF00769.19 CEP14968.1 - 0.22 11.3 40.3 0.096 12.5 22.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family zf-C3HC4_3 PF13920.6 CEP14968.1 - 0.27 11.1 5.5 0.057 13.3 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2353 PF09789.9 CEP14968.1 - 0.35 10.2 41.4 0.94 8.8 13.1 2.3 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) FokI_N PF02981.15 CEP14968.1 - 0.39 10.9 5.6 0.43 10.8 0.4 2.9 2 1 1 3 3 3 0 Restriction endonuclease FokI, recognition domain CLZ PF16526.5 CEP14968.1 - 0.65 10.4 25.2 0.29 11.5 4.5 4.9 4 3 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-RING_5 PF14634.6 CEP14968.1 - 0.94 9.5 7.8 0.15 12.0 1.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Zn_protease PF05618.11 CEP14968.1 - 1 9.2 7.2 0.29 11.0 1.3 2.5 2 1 1 3 3 3 0 Putative ATP-dependant zinc protease zf-rbx1 PF12678.7 CEP14968.1 - 1.6 9.1 4.4 0.61 10.4 1.1 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CEP14968.1 - 1.9 8.2 6.2 0.28 10.8 0.9 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF4248 PF14053.6 CEP14968.1 - 2 8.5 9.8 0.38 10.8 0.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) Lsr2 PF11774.8 CEP14968.1 - 4.6 7.4 9.0 7.3 6.8 2.9 3.4 2 2 1 3 3 3 0 Lsr2 AIP3 PF03915.13 CEP14969.1 - 1.3e-119 400.0 30.0 2.6e-119 399.0 30.0 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 HSBP1 PF06825.12 CEP14969.1 - 0.083 12.8 3.5 10 6.0 0.0 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 AKNA PF12443.8 CEP14969.1 - 0.33 11.6 8.1 0.23 12.1 3.9 3.2 3 0 0 3 3 3 0 AT-hook-containing transcription factor DUF1870 PF08965.10 CEP14969.1 - 1.3 9.1 6.6 8.1 6.5 1.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1870) F-box PF00646.33 CEP14970.1 - 0.017 15.0 0.2 0.075 12.9 0.0 2.3 2 0 0 2 2 2 0 F-box domain DUF1411 PF07199.11 CEP14970.1 - 0.03 14.0 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) COG5 PF10392.9 CEP14971.1 - 0.12 12.6 2.8 0.59 10.3 0.1 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 UBX PF00789.20 CEP14972.1 - 5.6e-17 61.7 0.5 9.9e-17 60.9 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 CEP14972.1 - 5.2e-05 23.1 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain VTC PF09359.10 CEP14972.1 - 0.035 13.5 7.3 0.047 13.1 7.3 1.2 1 0 0 1 1 1 0 VTC domain Borrelia_P83 PF05262.11 CEP14972.1 - 1.1 7.7 26.5 1.3 7.4 26.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hamartin PF04388.12 CEP14972.1 - 4.7 5.7 14.3 5.3 5.6 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.6 CEP14972.1 - 6 7.4 9.5 7.8 7.0 9.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SPRY PF00622.28 CEP14973.1 - 4e-22 78.6 0.2 6.1e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 SPRY domain RabGAP-TBC PF00566.18 CEP14975.1 - 7.9e-52 176.0 0.6 1.7e-51 174.9 0.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ala_racemase_N PF01168.20 CEP14975.1 - 3.6e-24 85.7 0.0 7.2e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA_SAD PF07973.14 CEP14977.1 - 0.4 10.8 2.4 15 5.8 0.2 3.0 2 1 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain AMP-binding PF00501.28 CEP14979.1 - 4.6e-61 206.7 0.1 1.4e-25 89.8 0.1 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 CEP14979.1 - 2.3e-08 34.8 9.9 1.3e-07 32.4 9.3 2.5 1 1 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 CEP14979.1 - 0.0065 16.5 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 Gas vesicle protein G Trimer_CC PF08954.11 CEP14979.1 - 0.81 9.3 2.7 2.3 7.9 2.7 1.7 1 0 0 1 1 1 0 Trimerisation motif Lin-8 PF03353.15 CEP14979.1 - 2.4 7.6 9.0 6 6.3 9.0 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Acetyltransf_1 PF00583.25 CEP14980.1 - 4.4e-11 43.1 0.0 7.3e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP14980.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP14980.1 - 1.3e-08 34.9 0.0 3.9e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEP14980.1 - 8.2e-05 22.7 0.0 0.00016 21.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CEP14980.1 - 0.00044 19.8 0.0 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 CEP14980.1 - 0.0055 16.6 0.0 0.042 13.8 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 CEP14980.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 CEP14980.1 - 0.036 14.2 0.0 0.088 13.0 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Cupin_8 PF13621.6 CEP14981.1 - 1.1e-72 244.9 0.1 1.3e-72 244.6 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain GPI PF06560.11 CEP14981.1 - 0.015 14.6 0.1 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.22 CEP14981.1 - 0.017 15.5 0.3 0.47 10.9 0.0 2.6 3 0 0 3 3 3 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 CEP14981.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Rgp1 PF08737.10 CEP14982.1 - 3e-98 329.8 2.2 3e-98 329.8 2.2 2.4 2 1 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 CEP14982.1 - 2.6e-05 24.7 0.1 0.13 12.7 0.0 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP14982.1 - 0.084 12.9 0.5 0.39 10.8 0.1 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain PEMT PF04191.13 CEP14983.1 - 4.5e-52 174.9 15.9 3e-32 111.2 0.4 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 CEP14983.1 - 4.1e-06 26.6 0.3 2.9e-05 23.8 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 CEP14983.1 - 4.9e-06 27.0 0.0 2.8e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 SKICH domain ApoLp-III PF07464.11 CEP14983.1 - 0.0046 17.1 2.9 0.0082 16.2 2.9 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) EspB PF05802.11 CEP14983.1 - 0.016 15.2 1.0 0.027 14.5 1.0 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein Sec10 PF07393.11 CEP14983.1 - 0.073 11.5 0.6 0.11 10.9 0.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Apolipoprotein PF01442.18 CEP14983.1 - 0.35 10.7 4.3 1.5 8.7 2.2 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEP14983.1 - 1.4 9.5 3.9 0.7 10.5 1.3 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribophorin_I PF04597.14 CEP14984.1 - 2.2e-117 393.0 8.3 6e-117 391.5 8.3 1.7 1 1 0 1 1 1 1 Ribophorin I VIT1 PF01988.19 CEP14984.1 - 1.5e-70 237.4 0.0 3.2e-70 236.3 0.0 1.6 1 0 0 1 1 1 1 VIT family DUF5370 PF17340.2 CEP14984.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Amino_oxidase PF01593.24 CEP14985.1 - 2.3e-24 86.5 0.0 3.9e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP14985.1 - 8.1e-10 38.8 0.1 2.2e-09 37.4 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP14985.1 - 1.6e-06 28.0 0.0 1.5e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CEP14985.1 - 1.1e-05 24.8 0.1 3.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CEP14985.1 - 0.00037 19.8 0.1 0.041 13.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP14985.1 - 0.00043 20.8 0.6 0.33 11.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP14985.1 - 0.0043 17.0 0.1 0.41 10.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 CEP14985.1 - 0.012 14.4 1.0 0.067 12.0 0.0 2.0 2 0 0 2 2 2 0 MCRA family HI0933_like PF03486.14 CEP14985.1 - 0.021 13.5 0.3 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NUC130_3NT PF08158.12 CEP14985.1 - 0.07 13.5 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 NUC130/3NT domain Trp_halogenase PF04820.14 CEP14985.1 - 0.082 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 CEP14985.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 CEP14985.1 - 0.12 11.7 0.1 0.86 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Arrestin_C PF02752.22 CEP14986.1 - 1.5e-17 64.3 0.4 5.7e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP14986.1 - 1.6e-13 51.0 0.0 3.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP14986.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like SPT6_acidic PF14632.6 CEP14986.1 - 0.05 14.2 0.1 0.094 13.3 0.1 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF3149 PF11346.8 CEP14987.1 - 0.28 10.8 3.4 0.52 10.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Ank_4 PF13637.6 CEP14988.1 - 1.2e-07 32.2 0.0 0.00062 20.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP14988.1 - 6.5e-06 26.3 0.1 0.12 12.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP14988.1 - 5.4e-05 23.5 0.0 0.00056 20.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CEP14988.1 - 0.00026 21.5 0.0 0.016 15.8 0.0 2.4 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP14988.1 - 0.0017 18.7 0.3 2.4 9.0 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeat YL1_C PF08265.11 CEP14989.1 - 2.1e-17 62.6 0.4 4.2e-17 61.6 0.4 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA PF00004.29 CEP14990.1 - 1.4e-41 142.0 0.0 2.7e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEP14990.1 - 2.7e-10 40.0 0.2 5.5e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CEP14990.1 - 3.9e-10 39.4 0.6 7.3e-10 38.5 0.6 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CEP14990.1 - 4.9e-06 26.8 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEP14990.1 - 2.1e-05 23.8 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEP14990.1 - 4.1e-05 23.9 0.2 0.03 14.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CEP14990.1 - 9.4e-05 22.4 0.3 0.0011 19.0 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP14990.1 - 0.00016 22.1 0.2 0.0071 16.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP14990.1 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CEP14990.1 - 0.0039 17.7 0.1 0.0099 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 CEP14990.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CEP14990.1 - 0.0073 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP14990.1 - 0.0079 16.2 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 CEP14990.1 - 0.018 14.4 0.6 0.28 10.5 0.1 2.6 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.6 CEP14990.1 - 0.021 15.1 0.3 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 CEP14990.1 - 0.022 14.4 0.0 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 CEP14990.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CEP14990.1 - 0.048 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NB-ARC PF00931.22 CEP14990.1 - 0.061 12.5 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF1128 PF06569.11 CEP14990.1 - 0.072 13.1 0.1 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DUF2075 PF09848.9 CEP14990.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CEP14990.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CEP14990.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CEP14990.1 - 0.15 12.0 0.1 0.8 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 CEP14990.1 - 0.15 11.7 0.7 0.37 10.5 0.3 1.9 2 1 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 CEP14990.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CEP14990.1 - 0.34 10.5 1.2 4.7 6.7 0.3 2.5 1 1 1 2 2 2 0 AAA domain TatD_DNase PF01026.21 CEP14991.1 - 1.5e-53 181.8 0.0 1.9e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Prefoldin PF02996.17 CEP14992.1 - 6.4e-20 71.3 0.9 7e-20 71.1 0.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CEP14992.1 - 0.019 14.9 1.6 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF2781 PF10914.8 CEP14993.1 - 1.9e-41 141.9 13.3 2.3e-41 141.6 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Polysacc_deac_1 PF01522.21 CEP14994.1 - 6.6e-10 39.0 0.5 1.7e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DEAD PF00270.29 CEP14995.1 - 2.4e-49 167.5 0.0 4.9e-49 166.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP14995.1 - 2.2e-30 105.3 0.0 7.4e-30 103.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP14995.1 - 2.3e-06 27.7 0.0 5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CEP14995.1 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GRP PF07172.11 CEP14995.1 - 2.2 9.0 15.0 5.7 7.7 15.0 1.7 1 0 0 1 1 1 0 Glycine rich protein family MARVEL PF01284.23 CEP14996.1 - 5.3e-13 49.2 11.1 7.7e-13 48.7 11.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 CEP14996.1 - 7.5e-05 22.5 6.6 0.0004 20.2 6.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF588) NSP2_assoc PF14758.6 CEP14996.1 - 0.097 13.0 0.1 0.22 11.8 0.1 1.4 1 1 1 2 2 2 0 Non-essential region of nsp2 of arterivirus polyprotein Ni_hydr_CYTB PF01292.20 CEP14996.1 - 0.8 9.3 7.7 0.13 11.8 0.7 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2408 PF10303.9 CEP14997.1 - 7.5e-06 26.6 0.1 9.6e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CZB PF13682.6 CEP14997.1 - 0.027 14.9 0.4 0.77 10.2 0.1 2.3 2 1 0 2 2 2 0 Chemoreceptor zinc-binding domain Rx_N PF18052.1 CEP14997.1 - 0.045 14.0 0.2 1.9 8.8 0.1 2.3 2 1 0 2 2 2 0 Rx N-terminal domain Apolipoprotein PF01442.18 CEP14997.1 - 0.057 13.3 0.5 0.12 12.3 0.5 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5089 PF17002.5 CEP14997.1 - 0.071 13.0 0.1 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) KxDL PF10241.9 CEP14997.1 - 0.18 12.1 1.9 21 5.4 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein PPR_2 PF13041.6 CEP14998.1 - 2.7e-44 149.1 13.7 2.2e-13 50.1 0.0 8.2 4 1 4 8 8 8 6 PPR repeat family PPR_3 PF13812.6 CEP14998.1 - 6e-39 132.0 1.0 6.2e-09 35.8 0.0 6.1 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP14998.1 - 5.6e-34 115.5 3.7 2e-06 27.4 0.0 7.6 8 1 0 8 8 8 5 PPR repeat PPR PF01535.20 CEP14998.1 - 6e-33 110.8 13.6 4.6e-06 26.5 0.1 9.9 9 1 0 9 9 9 5 PPR repeat PPR_long PF17177.4 CEP14998.1 - 3e-19 69.2 5.1 9.8e-09 34.9 0.1 3.9 2 2 3 5 5 5 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CEP14998.1 - 1.7e-06 27.9 7.2 0.62 9.9 0.1 5.5 2 1 5 7 7 7 3 Mitochondrial ATPase expression RhoGAP PF00620.27 CEP14998.1 - 0.28 11.0 2.7 4.2 7.2 0.7 2.9 3 0 0 3 3 3 0 RhoGAP domain DUF4709 PF15821.5 CEP14998.1 - 0.41 10.9 3.6 28 5.0 0.2 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) Ribosomal_L11 PF00298.19 CEP15000.1 - 5.9e-29 100.4 1.0 1.1e-28 99.5 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CEP15000.1 - 1.1e-24 86.0 0.4 1.7e-24 85.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF2785 PF10978.8 CEP15001.1 - 0.039 13.7 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Pkinase PF00069.25 CEP15002.1 - 3.9e-56 190.3 0.0 8.2e-56 189.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15002.1 - 5.2e-26 91.5 0.0 8.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15002.1 - 0.0061 15.9 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP15002.1 - 0.045 13.1 0.3 0.094 12.1 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM92 PF06730.11 CEP15003.1 - 0.01 15.3 5.0 0.017 14.6 4.1 1.6 1 1 1 2 2 2 0 FAM92 protein ISG65-75 PF11727.8 CEP15003.1 - 0.011 15.0 6.2 0.013 14.7 5.5 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein Helicase_RecD PF05127.14 CEP15003.1 - 0.019 14.8 1.3 0.035 14.0 0.1 2.1 2 1 0 2 2 2 0 Helicase Oxidored-like PF09791.9 CEP15003.1 - 0.14 11.8 0.3 0.36 10.5 0.3 1.7 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal CLP_protease PF00574.23 CEP15003.1 - 0.17 11.7 7.0 0.11 12.4 0.6 2.8 2 1 1 3 3 3 0 Clp protease ALMT PF11744.8 CEP15003.1 - 0.32 9.8 10.2 0.39 9.5 10.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3450 PF11932.8 CEP15003.1 - 7 5.9 15.7 0.53 9.6 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Iwr1 PF08574.10 CEP15004.1 - 2.9e-14 53.8 18.2 2.9e-14 53.8 18.2 3.7 3 2 1 4 4 4 1 Transcription factor Iwr1 Kelch_4 PF13418.6 CEP15005.1 - 6.1e-42 141.4 10.2 2.6e-08 33.8 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP15005.1 - 2.7e-41 138.9 10.1 4.5e-07 29.3 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 CEP15005.1 - 2.1e-39 132.9 12.0 3.9e-07 29.9 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CEP15005.1 - 2.9e-37 126.3 15.2 7.5e-09 35.7 0.1 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP15005.1 - 1.9e-34 116.8 16.9 1e-06 28.8 0.1 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 CEP15005.1 - 7.2e-32 108.2 7.5 1.9e-05 24.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif SelP_N PF04592.14 CEP15005.1 - 2.2 7.6 8.4 3.3 7.0 8.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MOR2-PAG1_N PF14222.6 CEP15009.1 - 0.036 13.0 0.1 0.04 12.9 0.1 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Sugar_tr PF00083.24 CEP15010.1 - 7.1e-90 302.0 15.5 3.5e-89 299.7 15.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP15010.1 - 6e-29 101.1 48.1 4.3e-27 95.0 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CEP15010.1 - 8.1e-06 25.4 5.3 8.1e-06 25.4 5.3 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 CEP15010.1 - 0.00087 17.7 3.9 0.031 12.6 2.8 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CDK2AP PF09806.9 CEP15011.1 - 0.34 10.9 14.8 0.027 14.6 7.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3720 PF12517.8 CEP15011.1 - 0.69 10.9 5.3 0.53 11.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) FAM76 PF16046.5 CEP15011.1 - 0.92 8.8 8.2 0.21 10.9 4.6 1.7 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 CEP15011.1 - 6.9 5.3 6.0 13 4.4 6.0 1.4 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 CEP15012.1 - 0.00021 21.0 0.1 0.00027 20.6 0.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BSP_II PF05432.11 CEP15012.1 - 0.00026 20.8 8.6 0.00033 20.4 8.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.13 CEP15012.1 - 0.00096 19.1 2.2 0.0015 18.5 2.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF913 PF06025.12 CEP15012.1 - 0.0051 15.8 0.2 0.0064 15.5 0.2 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) TLP-20 PF06088.11 CEP15012.1 - 0.029 14.3 1.6 0.036 14.0 1.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 CEP15012.1 - 0.031 14.5 0.3 0.043 14.0 0.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 CEP15012.1 - 0.037 13.2 0.3 0.04 13.1 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RXT2_N PF08595.11 CEP15012.1 - 0.13 12.3 5.3 0.19 11.7 5.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Presenilin PF01080.17 CEP15012.1 - 0.16 10.7 0.2 0.18 10.6 0.2 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CEP15012.1 - 0.17 10.1 6.9 0.2 9.9 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 CEP15012.1 - 0.4 11.1 3.5 0.61 10.5 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 CEP15012.1 - 0.46 8.6 11.6 0.58 8.3 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family IMUP PF15761.5 CEP15012.1 - 0.46 11.2 10.0 0.74 10.5 10.0 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein TRAP_alpha PF03896.16 CEP15012.1 - 0.54 9.4 3.6 0.77 8.9 3.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4050 PF13259.6 CEP15012.1 - 0.55 10.5 7.7 0.06 13.7 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Tim54 PF11711.8 CEP15012.1 - 0.81 8.4 3.8 1.1 7.9 3.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 CEP15012.1 - 0.83 8.1 4.0 1.1 7.7 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 CEP15012.1 - 0.99 8.9 11.0 1.3 8.6 11.0 1.1 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 CEP15012.1 - 1.3 8.4 13.8 1.7 8.0 13.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CEP15012.1 - 1.4 8.3 13.6 1.9 7.8 13.6 1.1 1 0 0 1 1 1 0 SDA1 GOLD_2 PF13897.6 CEP15012.1 - 2.3 8.7 6.2 4.8 7.7 6.2 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NPR3 PF03666.13 CEP15012.1 - 4.9 5.8 6.9 7.1 5.3 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIGA PF08288.12 CEP15013.1 - 5.2e-45 151.9 0.5 1.2e-44 150.8 0.5 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CEP15013.1 - 2e-29 102.8 1.1 3.3e-29 102.0 0.4 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CEP15013.1 - 9.4e-23 80.6 0.0 1.6e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP15013.1 - 1e-19 71.3 0.1 2e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEP15013.1 - 3.9e-11 43.6 0.0 6.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CEP15013.1 - 1.2e-06 28.6 0.2 2.4e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like CTP_transf_like PF01467.26 CEP15014.1 - 6.5e-30 104.2 0.0 1.1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 CEP15014.1 - 0.017 15.3 0.0 0.08 13.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 CEP15014.1 - 0.1 13.2 0.1 0.48 11.1 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5499) ASXH PF13919.6 CEP15016.1 - 2.1e-18 66.6 1.9 2.1e-18 66.6 1.9 2.5 2 0 0 2 2 2 1 Asx homology domain RhoGAP PF00620.27 CEP15017.1 - 1.1e-48 164.9 0.0 5e-48 162.8 0.0 2.3 1 0 0 1 1 1 1 RhoGAP domain Pribosyltran_N PF13793.6 CEP15017.1 - 2.3e-41 140.4 0.4 1.4e-40 137.9 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEP15017.1 - 1.7e-32 112.9 3.6 1.7e-32 112.9 3.6 3.8 3 1 0 3 3 3 1 Phosphoribosyl synthetase-associated domain RasGEF_N PF00618.20 CEP15017.1 - 4.1e-22 78.4 6.7 8e-13 48.5 2.6 4.8 4 1 0 4 4 4 2 RasGEF N-terminal motif RasGEF PF00617.19 CEP15017.1 - 1.9e-21 77.1 1.0 1e-13 51.9 0.1 4.3 4 0 0 4 4 4 2 RasGEF domain PH_9 PF15410.6 CEP15017.1 - 5.1e-19 68.8 4.2 3.3e-13 50.1 0.0 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.29 CEP15017.1 - 1.4e-12 48.1 0.4 1.7e-06 28.5 0.0 3.1 2 0 0 2 2 2 2 PH domain Pribosyltran PF00156.27 CEP15017.1 - 7.9e-07 28.7 0.1 1.2e-05 24.9 0.1 3.0 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Lge1 PF11488.8 CEP15017.1 - 0.082 13.1 0.9 0.76 10.0 0.6 3.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HSF_DNA-bind PF00447.17 CEP15018.1 - 3e-33 114.3 2.5 6.5e-33 113.2 2.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4472 PF14739.6 CEP15018.1 - 0.046 14.5 0.7 0.28 11.9 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Cdc6_C PF09079.11 CEP15018.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Rb_C PF08934.10 CEP15018.1 - 1.9 8.3 6.9 2.7 7.8 0.3 2.4 2 0 0 2 2 2 0 Rb C-terminal domain DDE_Tnp_1_7 PF13843.6 CEP15019.1 - 6.2e-11 42.2 0.0 1.4e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Transposase IS4 DUF3813 PF12758.7 CEP15019.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Alpha_E3_glycop PF01563.16 CEP15019.1 - 0.4 10.8 1.9 0.86 9.7 0.1 2.4 2 0 0 2 2 2 0 Alphavirus E3 glycoprotein Aldedh PF00171.22 CEP15020.1 - 4.6e-65 219.9 0.0 4.6e-41 140.8 0.0 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CEP15020.1 - 0.021 13.9 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Far-17a_AIG1 PF04750.14 CEP15021.1 - 1.8e-36 125.3 10.4 2.1e-36 125.2 10.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein 2Fe-2S_thioredx PF01257.19 CEP15022.1 - 1.1e-59 200.5 0.1 1.4e-59 200.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DAGK_cat PF00781.24 CEP15023.1 - 9.4e-20 70.5 0.1 2.8e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.27 CEP15025.1 - 9.8e-36 123.3 0.0 2.3e-35 122.1 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 CEP15025.1 - 4.2e-35 121.7 10.9 7.1e-32 111.1 4.0 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CEP15025.1 - 1.8e-07 30.8 1.0 1.3e-05 24.8 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP15025.1 - 0.00042 20.6 0.2 0.0062 16.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain ABC_membrane_2 PF06472.15 CEP15025.1 - 0.00047 19.7 0.2 0.00093 18.7 0.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 APS_kinase PF01583.20 CEP15025.1 - 0.00071 19.5 0.0 0.0024 17.8 0.0 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.6 CEP15025.1 - 0.0021 17.6 0.0 0.055 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP15025.1 - 0.0025 18.2 0.1 0.009 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CEP15025.1 - 0.0046 17.5 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CEP15025.1 - 0.005 17.3 1.1 0.16 12.4 1.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEP15025.1 - 0.005 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.17 CEP15025.1 - 0.0056 16.4 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 CEP15025.1 - 0.0082 15.9 0.5 0.035 13.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CEP15025.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEP15025.1 - 0.044 13.8 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CEP15025.1 - 0.045 13.9 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 CEP15025.1 - 0.054 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DEAD PF00270.29 CEP15025.1 - 0.066 13.0 0.2 1.4 8.7 0.2 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 CEP15025.1 - 0.082 13.1 0.5 1 9.7 0.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CEP15025.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NPHI_C PF08469.10 CEP15025.1 - 0.09 12.8 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal AAA_30 PF13604.6 CEP15025.1 - 0.094 12.4 0.3 3.1 7.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP15025.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 CEP15025.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DDE_3 PF13358.6 CEP15026.1 - 1.5e-16 60.5 0.1 1.3e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease MarR_2 PF12802.7 CEP15026.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 CEP15026.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TrmB PF01978.19 CEP15026.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_S30 PF01577.16 CEP15026.1 - 0.26 10.9 2.6 0.16 11.5 0.7 1.6 2 0 0 2 2 2 0 Potyvirus P1 protease WD40 PF00400.32 CEP15027.1 - 1e-10 42.0 2.7 5.7 8.0 0.0 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15027.1 - 0.0012 19.1 0.2 19 5.6 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PH PF00169.29 CEP15028.1 - 3e-07 30.9 0.4 1.3e-05 25.7 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CEP15028.1 - 0.00041 20.7 0.0 0.00041 20.7 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain Homeodomain PF00046.29 CEP15030.1 - 6.1e-18 64.4 4.8 1.2e-17 63.5 4.8 1.5 1 0 0 1 1 1 1 Homeodomain MFS_5 PF05631.14 CEP15030.1 - 0.087 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM PCI PF01399.27 CEP15031.1 - 7.4e-11 42.5 0.9 6.1e-10 39.5 0.1 2.8 2 0 0 2 2 2 1 PCI domain Syntaxin-6_N PF09177.11 CEP15032.1 - 1.2e-26 93.2 2.7 3.2e-26 91.8 2.7 1.7 1 0 0 1 1 1 1 Syntaxin 6, N-terminal CENP-Q PF13094.6 CEP15032.1 - 0.00076 19.7 7.6 0.0015 18.8 7.6 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit FliJ PF02050.16 CEP15032.1 - 0.0049 17.1 10.1 0.12 12.6 1.6 2.7 2 1 0 2 2 2 2 Flagellar FliJ protein Uso1_p115_C PF04871.13 CEP15032.1 - 0.015 15.7 7.9 0.096 13.1 0.3 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SNARE PF05739.19 CEP15032.1 - 0.033 14.2 0.4 0.72 9.9 0.0 2.5 2 0 0 2 2 2 0 SNARE domain DUF5446 PF17522.2 CEP15032.1 - 0.054 13.7 1.2 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Sec34 PF04136.15 CEP15032.1 - 0.065 13.1 1.8 0.21 11.5 0.7 2.2 1 1 1 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 CEP15032.1 - 0.074 13.5 3.6 0.18 12.3 0.5 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RasGAP_C PF03836.15 CEP15032.1 - 0.12 12.5 4.1 0.093 12.9 1.6 1.9 1 1 1 2 2 2 0 RasGAP C-terminus DASH_Duo1 PF08651.10 CEP15032.1 - 0.16 11.8 6.8 3.3 7.6 0.1 3.2 4 1 0 4 4 4 0 DASH complex subunit Duo1 DUF745 PF05335.13 CEP15032.1 - 0.36 10.5 10.0 4.1 7.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CRR7 PF12095.8 CEP15032.1 - 0.69 10.4 6.1 36 4.9 0.1 3.3 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 CorA PF01544.18 CEP15032.1 - 1.3 8.3 6.6 0.86 8.9 2.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.12 CEP15032.1 - 4 7.5 9.9 0.96 9.5 4.3 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 CEP15032.1 - 6.9 7.0 6.1 15 5.9 0.8 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PhoLip_ATPase_C PF16212.5 CEP15033.1 - 6.1e-84 281.7 26.3 6.1e-84 281.7 26.3 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Ribonuclease_T2 PF00445.18 CEP15033.1 - 1.3e-30 107.0 0.3 5.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease T2 family PhoLip_ATPase_N PF16209.5 CEP15033.1 - 1.8e-25 88.4 7.4 1.6e-24 85.3 7.3 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEP15033.1 - 1.9e-13 50.3 0.0 1.8e-12 47.2 0.0 2.7 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP15033.1 - 1.6e-11 44.9 0.0 4.7e-06 27.0 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP15033.1 - 6.2e-05 22.6 0.0 0.00021 20.9 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP15033.1 - 0.0054 16.5 2.7 0.014 15.1 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase TFIID-31kDa PF02291.15 CEP15034.1 - 7.5e-50 168.1 0.0 8.7e-50 167.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP15034.1 - 6.1e-07 29.4 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CEP15034.1 - 0.001 19.5 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP15034.1 - 0.003 17.9 0.0 0.004 17.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID_30kDa PF03540.13 CEP15034.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit CENP-T_C PF15511.6 CEP15034.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CTP_transf_like PF01467.26 CEP15035.1 - 1.1e-44 152.1 0.2 2.4e-27 95.9 0.0 2.5 2 1 1 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 CEP15035.1 - 0.00035 20.5 0.4 0.99 9.3 0.0 2.7 2 1 0 2 2 2 2 FAD synthetase ScdA_N PF04405.14 CEP15035.1 - 0.018 14.7 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) F-box-like PF12937.7 CEP15037.1 - 2.5e-09 36.9 0.0 2.1e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP15037.1 - 0.0005 19.9 0.0 0.002 18.0 0.0 2.1 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 CEP15038.1 - 2.1e-71 240.4 0.0 4.3e-71 239.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15038.1 - 5.5e-53 179.9 0.0 8.9e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15038.1 - 2.9e-06 26.8 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 CEP15038.1 - 0.00054 19.6 0.0 0.0022 17.6 0.0 2.0 1 1 0 1 1 1 1 RIO1 family C1_1 PF00130.22 CEP15038.1 - 0.0021 17.9 9.1 0.0021 17.9 9.1 2.0 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CEP15038.1 - 0.11 12.6 4.8 0.34 11.0 4.8 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CEP15038.1 - 0.26 11.2 6.6 0.58 10.1 6.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 CEP15038.1 - 0.42 10.3 7.9 0.93 9.2 7.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CEP15038.1 - 6.4 7.2 10.9 18 5.7 10.9 1.8 1 0 0 1 1 1 0 RING-like domain Ras PF00071.22 CEP15039.1 - 3.5e-51 173.0 0.0 4.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15039.1 - 3.1e-18 66.1 0.0 5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15039.1 - 3.2e-08 33.2 0.0 4.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEP15039.1 - 2.9e-06 27.3 0.1 0.052 13.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEP15039.1 - 2.8e-05 23.8 0.0 5.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP15039.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP15039.1 - 0.028 13.9 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 CEP15039.1 - 0.045 13.3 0.6 0.25 10.9 0.6 2.0 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 CEP15040.1 - 1.1e-37 127.3 17.4 4.9e-08 33.5 0.2 7.4 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15040.1 - 1.6e-05 25.1 1.3 1.5 9.2 0.1 5.3 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AP-5_subunit_s1 PF15001.6 CEP15040.1 - 0.012 15.6 0.9 0.023 14.7 0.9 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 WD40_like PF17005.5 CEP15040.1 - 0.042 13.2 0.0 0.2 10.9 0.0 2.2 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 CEP15040.1 - 0.053 12.2 2.9 9.1 4.8 0.2 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 CN_hydrolase PF00795.22 CEP15041.1 - 5.3e-12 45.6 0.1 3.2e-11 43.1 0.1 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SAP PF02037.27 CEP15042.1 - 5.9e-13 48.2 1.6 5.9e-13 48.2 1.6 1.7 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 CEP15042.1 - 8.2e-05 22.3 14.3 0.0023 17.7 0.4 4.5 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain Med3 PF11593.8 CEP15042.1 - 0.021 14.0 10.5 0.025 13.8 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HeH PF12949.7 CEP15042.1 - 0.021 14.5 1.5 0.064 13.0 1.5 1.9 1 0 0 1 1 1 0 HeH/LEM domain Mycoplasma_p37 PF06646.11 CEP15042.1 - 0.46 9.7 4.1 0.92 8.7 3.0 1.8 2 0 0 2 2 2 0 High affinity transport system protein p37 Kelch_4 PF13418.6 CEP15044.1 - 1.4e-17 63.4 13.9 0.00033 20.6 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP15044.1 - 7.7e-16 57.7 13.2 0.0046 16.9 0.1 6.8 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEP15044.1 - 4.6e-14 51.7 4.4 0.0033 17.3 0.0 6.7 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.6 CEP15044.1 - 6.3e-14 51.7 12.0 0.0018 18.5 0.1 6.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CEP15044.1 - 1.9e-09 36.9 5.2 0.0011 18.6 0.0 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 CEP15044.1 - 2.5e-08 34.0 21.5 0.072 13.4 0.4 6.8 6 1 1 7 7 7 3 Galactose oxidase, central domain ASC PF00858.24 CEP15044.1 - 0.00018 20.6 1.2 0.12 11.3 0.0 3.3 3 0 0 3 3 3 1 Amiloride-sensitive sodium channel YqhR PF11085.8 CEP15044.1 - 0.026 14.5 0.1 0.026 14.5 0.1 1.8 2 0 0 2 2 1 0 Conserved membrane protein YqhR Glyoxal_oxid_N PF07250.11 CEP15044.1 - 0.049 12.8 0.1 0.2 10.8 0.0 2.0 2 1 0 2 2 2 0 Glyoxal oxidase N-terminus DUF5074 PF16819.5 CEP15044.1 - 0.077 13.1 0.5 0.29 11.2 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) GLEYA PF10528.9 CEP15044.1 - 1.6 9.2 5.8 11 6.5 0.5 3.4 3 0 0 3 3 3 0 GLEYA domain CTP_transf_like PF01467.26 CEP15045.1 - 3.7e-06 27.2 0.0 6.5e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like Peptidase_C14 PF00656.22 CEP15046.1 - 3.7e-47 161.4 0.1 7.6e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 Caspase domain Proteasome PF00227.26 CEP15046.1 - 1e-36 126.2 0.1 2.2e-36 125.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit Snf7 PF03357.21 CEP15046.1 - 1.1e-24 87.0 6.9 1.1e-24 87.0 6.9 2.3 2 0 0 2 2 2 1 Snf7 Brix PF04427.18 CEP15047.1 - 8e-34 117.4 0.2 1.1e-33 117.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain DnaJ_C PF01556.18 CEP15048.1 - 3.1e-44 150.6 1.3 4e-44 150.3 1.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP15048.1 - 5.1e-26 90.6 3.7 9.1e-26 89.8 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP15048.1 - 2.4e-13 50.2 21.3 4.5e-13 49.3 21.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CEP15048.1 - 0.00047 20.1 2.7 0.00047 20.1 2.7 2.5 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CEP15048.1 - 0.0087 16.1 12.3 0.048 13.7 3.9 2.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Snurportin1 PF11538.8 CEP15049.1 - 0.00021 21.4 6.8 0.00043 20.4 6.8 1.5 1 0 0 1 1 1 1 Snurportin1 IBB PF01749.20 CEP15049.1 - 0.86 10.1 11.7 2.8 8.4 11.7 1.9 1 1 0 1 1 1 0 Importin beta binding domain adh_short PF00106.25 CEP15050.1 - 5.3e-36 123.9 0.0 6.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP15050.1 - 4e-27 95.3 0.0 5.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP15050.1 - 6.3e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CEP15050.1 - 0.0048 15.9 0.1 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_1 PF00515.28 CEP15051.1 - 1.2e-17 62.9 5.2 0.0009 19.0 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP15051.1 - 3.4e-15 55.4 4.0 0.0011 18.6 0.0 4.6 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.17 CEP15051.1 - 2.6e-14 52.1 8.7 0.00092 19.2 0.2 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP15051.1 - 1.3e-10 40.6 1.7 0.16 12.2 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP15051.1 - 2.2e-10 40.2 3.4 0.0065 16.8 0.1 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP15051.1 - 9e-10 38.9 6.1 4.3e-05 23.9 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP15051.1 - 8.5e-09 35.9 7.1 0.0003 21.4 0.0 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 CEP15051.1 - 2.2e-08 34.3 1.0 0.023 15.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CEP15051.1 - 4.2e-07 30.2 11.2 0.3 12.0 1.1 5.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEP15051.1 - 1.2e-05 25.5 11.0 0.027 14.7 0.7 4.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 CEP15051.1 - 6.1e-05 23.1 4.7 0.11 12.7 0.1 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP15051.1 - 0.00012 21.8 7.0 0.31 11.1 0.3 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP15051.1 - 0.011 16.3 0.1 0.044 14.4 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1641 PF07849.11 CEP15051.1 - 0.15 12.0 0.2 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TPR_6 PF13174.6 CEP15051.1 - 0.19 12.4 0.9 9.7 7.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP15051.1 - 0.2 11.9 5.5 0.17 12.1 0.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEP15051.1 - 7.7 6.5 10.8 0.58 10.1 1.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ERCC4 PF02732.15 CEP15052.1 - 1.5e-14 54.5 0.1 1.5e-14 54.5 0.1 2.3 1 1 1 2 2 2 1 ERCC4 domain CUE PF02845.16 CEP15052.1 - 0.033 13.9 0.0 0.093 12.5 0.0 1.8 1 0 0 1 1 1 0 CUE domain CAF-1_p150 PF11600.8 CEP15052.1 - 0.052 13.3 27.8 0.11 12.2 27.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.6 CEP15052.1 - 1.1 9.7 15.9 0.043 14.3 9.1 2.2 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.9 CEP15052.1 - 4.8 6.2 13.6 1.2 8.1 8.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_pol_Rpc4 PF05132.14 CEP15052.1 - 9.8 6.6 8.8 33 4.9 8.8 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 MIEAP PF16026.5 CEP15056.1 - 0.82 9.9 4.3 0.79 9.9 2.7 1.7 1 1 1 2 2 2 0 Mitochondria-eating protein DUF4460 PF14687.6 CEP15058.1 - 1.3e-08 34.9 0.1 2.5e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Pox_C7_F8A PF03287.14 CEP15058.1 - 0.15 12.0 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 Poxvirus C7/F8A protein NAD_binding_4 PF07993.12 CEP15059.1 - 0.0077 15.4 0.0 0.029 13.5 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Mito_carr PF00153.27 CEP15060.1 - 2.9e-42 142.5 9.4 4e-17 61.9 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP15060.1 - 3.9e-06 26.2 2.9 0.024 13.8 0.2 3.1 3 0 0 3 3 3 3 Gammaproteobacterial serine protease DUF5518 PF17647.1 CEP15060.1 - 0.037 14.2 6.9 0.88 9.7 2.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Glyco_hydro_18 PF00704.28 CEP15061.1 - 2.1e-74 251.0 3.0 2.8e-74 250.7 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CEP15061.1 - 0.00019 21.4 2.3 0.00019 21.4 2.3 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) Toxin_20 PF08089.11 CEP15061.1 - 0.044 13.9 0.7 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Huwentoxin-II family Zn_clus PF00172.18 CEP15062.1 - 4.3e-09 36.3 7.1 1e-08 35.1 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 CEP15062.1 - 0.076 13.1 13.0 0.1 12.7 1.4 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TLD PF07534.16 CEP15063.1 - 1.1e-24 87.2 0.8 2.1e-24 86.3 0.8 1.5 1 0 0 1 1 1 1 TLD WBS_methylT PF12589.8 CEP15063.1 - 0.4 11.5 0.1 0.4 11.5 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome ErmC PF06308.11 CEP15064.1 - 0.034 14.5 0.2 0.058 13.7 0.2 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) Amido_AtzD_TrzD PF09663.10 CEP15067.1 - 0.11 11.5 0.4 1.2 8.1 0.1 1.9 1 1 1 2 2 2 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) RT_RNaseH PF17917.1 CEP15068.1 - 5.7e-26 90.9 0.0 1.2e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP15068.1 - 1.6e-22 79.4 0.0 3.7e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP15068.1 - 2.4e-12 47.1 0.0 6.4e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP15068.1 - 4.5e-07 29.7 1.7 1.2e-06 28.3 1.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 CEP15071.1 - 9.2e-28 96.6 0.1 2.2e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP15071.1 - 6e-23 80.8 1.1 4.3e-16 58.8 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase ErmC PF06308.11 CEP15071.1 - 2.6e-06 27.7 1.5 0.082 13.3 0.1 2.7 2 0 0 2 2 2 2 23S rRNA methylastransferase leader peptide (ErmCL) UPF0561 PF10573.9 CEP15071.1 - 0.0037 17.4 0.0 3.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0561 Phage_integrase PF00589.22 CEP15071.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Phage integrase family TMEM70 PF06979.12 CEP15074.1 - 0.031 14.7 0.1 0.056 13.9 0.1 1.4 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex NADHdh-2_N PF12155.8 CEP15074.1 - 0.047 14.1 0.1 0.074 13.4 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal PH PF00169.29 CEP15075.1 - 1.9e-09 38.0 12.2 0.00054 20.4 0.0 4.8 4 1 0 4 4 4 3 PH domain PH_15 PF17339.2 CEP15075.1 - 0.02 14.8 0.8 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 PH domain PH_9 PF15410.6 CEP15075.1 - 0.91 9.9 13.1 23 5.4 0.1 4.9 5 0 0 5 5 5 0 Pleckstrin homology domain CSD PF00313.22 CEP15076.1 - 6.3e-10 38.8 0.0 0.00043 20.1 0.0 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain SMN PF06003.12 CEP15076.1 - 0.11 11.7 0.9 0.2 10.9 0.9 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SUIM_assoc PF16619.5 CEP15076.1 - 0.25 11.4 6.7 1.4 9.1 2.2 2.8 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DASH_Duo1 PF08651.10 CEP15077.1 - 1.3e-05 24.9 4.9 0.0011 18.7 0.5 2.4 2 1 0 2 2 2 2 DASH complex subunit Duo1 DUF948 PF06103.11 CEP15077.1 - 2.4e-05 24.5 6.4 0.00032 20.9 1.7 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) BORCS7 PF16088.5 CEP15077.1 - 0.00029 21.0 4.8 0.00049 20.3 4.8 1.4 1 1 0 1 1 1 1 BLOC-1-related complex sub-unit 7 SesA PF17107.5 CEP15077.1 - 0.0004 20.6 3.2 0.028 14.6 0.2 2.2 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases BLOC1_2 PF10046.9 CEP15077.1 - 0.00082 19.6 5.9 0.0018 18.5 5.8 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DHR10 PF18595.1 CEP15077.1 - 0.00097 19.2 2.0 0.0013 18.8 2.0 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain DUF3450 PF11932.8 CEP15077.1 - 0.0015 17.9 1.8 0.0018 17.6 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 CEP15077.1 - 0.0022 18.0 6.1 0.0025 17.8 4.0 1.8 1 1 1 2 2 2 2 Laminin Domain II MCPsignal PF00015.21 CEP15077.1 - 0.0023 17.8 3.4 0.0031 17.3 3.4 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.13 CEP15077.1 - 0.0025 17.6 2.1 0.013 15.3 0.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF745) V_ATPase_I PF01496.19 CEP15077.1 - 0.003 15.5 1.2 0.0034 15.4 1.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family EzrA PF06160.12 CEP15077.1 - 0.0061 14.8 2.5 0.0077 14.5 2.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Syntaxin_2 PF14523.6 CEP15077.1 - 0.0067 16.8 5.2 0.021 15.2 3.4 2.0 1 1 1 2 2 2 2 Syntaxin-like protein GAS PF13851.6 CEP15077.1 - 0.011 15.1 2.6 0.015 14.7 2.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TDA11 PF17084.5 CEP15077.1 - 0.012 14.6 0.9 0.014 14.4 0.9 1.2 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 DUF2800 PF10926.8 CEP15077.1 - 0.015 14.5 0.2 0.016 14.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF2730 PF10805.8 CEP15077.1 - 0.016 15.3 2.3 0.03 14.4 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 CEP15077.1 - 0.025 14.6 5.3 0.29 11.2 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 CEP15077.1 - 0.029 13.3 4.1 0.043 12.8 4.0 1.3 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Med30 PF11315.8 CEP15077.1 - 0.031 14.5 1.8 0.34 11.1 1.5 2.1 1 1 0 1 1 1 0 Mediator complex subunit 30 RPW8 PF05659.11 CEP15077.1 - 0.033 13.9 2.0 0.27 10.9 1.4 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlgN PF05130.12 CEP15077.1 - 0.034 14.7 2.3 0.055 14.0 2.3 1.3 1 0 0 1 1 1 0 FlgN protein Gp-FAR-1 PF05823.12 CEP15077.1 - 0.035 14.5 2.0 0.094 13.1 1.9 1.8 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4252 PF14060.6 CEP15077.1 - 0.038 13.9 3.1 0.05 13.5 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) Nsp1_C PF05064.13 CEP15077.1 - 0.045 13.6 2.2 0.057 13.2 1.2 1.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region Sec34 PF04136.15 CEP15077.1 - 0.051 13.5 5.2 0.2 11.5 0.9 2.0 1 1 1 2 2 2 0 Sec34-like family YkyA PF10368.9 CEP15077.1 - 0.058 13.1 5.7 0.11 12.2 5.7 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Fib_alpha PF08702.10 CEP15077.1 - 0.072 13.3 4.3 0.072 13.3 1.8 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CEP15077.1 - 0.1 12.9 4.5 0.12 12.6 1.7 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 CEP15077.1 - 0.1 11.8 1.3 0.12 11.6 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.11 CEP15077.1 - 0.15 12.6 4.1 0.5 10.9 3.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF5082 PF16888.5 CEP15077.1 - 0.19 12.0 5.5 4.2 7.7 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ZapB PF06005.12 CEP15077.1 - 0.23 11.9 4.1 2.4 8.6 2.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB MSA-2c PF12238.8 CEP15077.1 - 0.23 11.5 3.3 0.9 9.5 1.0 1.9 1 1 1 2 2 2 0 Merozoite surface antigen 2c RecG_N PF17190.4 CEP15077.1 - 0.26 12.0 2.2 1.5 9.6 2.3 2.0 1 1 0 1 1 1 0 RecG N-terminal helical domain Baculo_PEP_C PF04513.12 CEP15077.1 - 0.4 10.7 6.9 1.5 8.9 7.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 CEP15077.1 - 0.94 10.0 6.0 2.4 8.7 6.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 CEP15077.1 - 1.5 9.3 8.7 4.9 7.7 3.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-H2C2_2 PF13465.6 CEP15078.1 - 1.5e-07 31.5 15.3 0.00013 22.2 2.9 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP15078.1 - 9.3e-06 25.8 8.7 3.8e-05 23.9 0.8 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf_Hakai PF18408.1 CEP15078.1 - 8e-05 22.3 6.4 0.014 15.1 0.3 3.2 3 0 0 3 3 3 2 C2H2 Hakai zinc finger domain zf-C2H2_4 PF13894.6 CEP15078.1 - 0.002 18.8 26.4 0.0022 18.7 0.6 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP15078.1 - 0.09 13.4 0.0 0.09 13.4 0.0 6.4 4 3 3 7 7 7 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CEP15078.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger RCR PF12273.8 CEP15078.1 - 0.52 11.0 4.8 1.4 9.6 4.8 1.8 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf_CopZ PF18423.1 CEP15078.1 - 1.4 9.0 4.1 4.7 7.2 0.0 3.5 4 0 0 4 4 4 0 Zinc binding domain RRM_1 PF00076.22 CEP15079.1 - 7.5e-06 25.7 0.1 1.5e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 CEP15079.1 - 0.0043 17.1 0.8 0.014 15.4 0.8 1.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Med18 PF09637.10 CEP15079.1 - 0.017 15.0 0.5 0.026 14.4 0.5 1.3 1 0 0 1 1 1 0 Med18 protein Prp19 PF08606.11 CEP15079.1 - 0.044 13.8 0.3 0.17 11.9 0.3 2.0 1 0 0 1 1 1 0 Prp19/Pso4-like LZ_Tnp_IS66 PF13007.7 CEP15079.1 - 0.15 12.8 2.1 1.3 9.8 0.0 2.7 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain ATP-synt PF00231.19 CEP15080.1 - 1.7e-75 254.4 4.8 1.9e-75 254.2 4.8 1.0 1 0 0 1 1 1 1 ATP synthase AHD PF17793.1 CEP15080.1 - 0.53 10.1 2.5 1.2 9.0 1.1 2.2 2 0 0 2 2 2 0 ANC1 homology domain (AHD) DBR1 PF05011.13 CEP15081.1 - 3.7e-38 131.1 0.8 7.1e-38 130.2 0.8 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CEP15081.1 - 1.3e-08 35.6 2.2 2.2e-08 34.9 2.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP15081.1 - 0.00095 19.4 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LOH1CR12 PF10158.9 CEP15082.1 - 4.7e-05 23.4 0.4 9.3e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 Tumour suppressor protein CmlA_N PF18456.1 CEP15082.1 - 0.0013 18.1 0.8 0.84 8.9 0.0 2.2 2 0 0 2 2 2 2 Diiron non-heme beta-hydroxylase N-terminal domain Goodbye PF17109.5 CEP15082.1 - 0.0026 18.2 0.1 0.005 17.3 0.1 1.5 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain DUF5117 PF17148.4 CEP15082.1 - 0.045 13.6 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) Acetyltransf_1 PF00583.25 CEP15083.1 - 3.3e-17 62.8 0.1 4.3e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP15083.1 - 6.4e-09 36.1 0.0 9.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP15083.1 - 1.6e-06 28.1 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP15083.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CEP15083.1 - 0.004 17.8 0.0 0.0059 17.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP15083.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SURF6 PF04935.12 CEP15084.1 - 1.1e-32 113.5 46.9 1.1e-32 113.5 46.9 3.0 1 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CEP15084.1 - 4.7e-19 68.7 5.3 4.7e-19 68.7 5.3 5.9 5 1 0 5 5 5 2 60S ribosome biogenesis protein Rrp14 eIF3_subunit PF08597.10 CEP15084.1 - 0.0055 16.6 22.2 0.0055 16.6 22.2 4.2 2 2 2 4 4 4 1 Translation initiation factor eIF3 subunit UPF0524 PF15823.5 CEP15084.1 - 0.27 10.6 3.6 0.95 8.8 3.6 1.9 1 0 0 1 1 1 0 UPF0524 of C3orf70 DIL PF01843.19 CEP15085.1 - 1.4e-26 92.8 3.8 5.9e-26 90.8 3.8 2.2 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CEP15085.1 - 4.8e-20 71.9 0.0 8.9e-13 48.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP15085.1 - 5.5e-10 39.6 0.0 0.00074 20.0 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEP15085.1 - 4.8e-08 33.1 0.0 0.007 16.8 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP15085.1 - 3e-06 27.4 0.0 0.001 19.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP15085.1 - 1.5e-05 25.0 0.0 0.071 13.7 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Cas_NE0113 PF09623.10 CEP15085.1 - 0.079 12.6 1.0 0.17 11.6 1.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Ank_2 PF12796.7 CEP15086.1 - 3.1e-31 107.8 0.1 6.9e-16 58.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP15086.1 - 1e-29 102.5 0.3 2.1e-07 31.4 0.1 5.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP15086.1 - 6.5e-24 83.7 2.0 5.8e-07 29.7 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP15086.1 - 1.9e-21 73.8 2.5 0.00038 20.7 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CEP15086.1 - 2.7e-19 68.7 0.7 0.0008 19.7 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 CEP15086.1 - 1.3e-16 60.4 9.0 2.5e-16 59.6 9.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger EF-hand_7 PF13499.6 CEP15087.1 - 4e-07 30.4 2.6 7.5e-07 29.5 2.6 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CEP15087.1 - 1.3e-06 27.9 0.6 3.2e-06 26.6 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CEP15087.1 - 2.5e-05 23.5 2.1 5.7e-05 22.4 2.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CEP15087.1 - 7.6e-05 22.0 3.6 8.1e-05 21.9 1.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CEP15087.1 - 0.86 9.5 5.3 0.46 10.4 1.1 2.2 1 1 1 2 2 2 0 EF-hand domain pair RRM_1 PF00076.22 CEP15088.1 - 1.2e-27 95.5 0.0 2e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CEP15088.1 - 3.7e-23 79.9 1.2 3.3e-06 26.5 0.1 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 CEP15088.1 - 5.4e-06 26.2 0.0 0.022 14.6 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 CEP15088.1 - 0.001 18.6 0.0 0.023 14.2 0.0 2.8 3 0 0 3 3 3 1 RNA-recognition motif RRM_3 PF08777.11 CEP15088.1 - 0.0046 17.0 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif SET_assoc PF11767.8 CEP15088.1 - 0.085 12.5 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 CEP15088.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 RRM-like domain RNA_bind PF08675.11 CEP15088.1 - 0.15 12.1 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain Peroxin-13_N PF04088.13 CEP15089.1 - 1.7e-46 158.1 1.0 2.5e-46 157.5 1.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 CEP15089.1 - 2.9e-13 49.2 0.0 5.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP15089.1 - 3.6e-11 42.8 0.0 7.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP15089.1 - 8.8e-11 41.3 0.0 1.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PMG PF05287.12 CEP15089.1 - 0.043 13.8 1.7 0.065 13.3 1.7 1.3 1 0 0 1 1 1 0 PMG protein Pex2_Pex12 PF04757.14 CEP15089.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Mei5_like PF17021.5 CEP15090.1 - 2.4 8.3 6.0 5.4 7.1 1.0 2.8 2 1 0 2 2 2 0 Putative double-strand recombination repair-like NUDIX PF00293.28 CEP15091.1 - 3.1e-31 108.1 0.0 4.3e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.24 CEP15096.1 - 9.7e-33 114.1 24.5 9.7e-33 114.1 24.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CEP15096.1 - 1.2e-15 57.4 0.0 2.9e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC2_membrane PF01061.24 CEP15097.1 - 1.8e-81 272.5 69.7 1.6e-47 161.7 20.5 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEP15097.1 - 9.8e-36 123.3 2.3 2.7e-19 70.0 0.0 3.4 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 CEP15097.1 - 1.2e-30 105.2 0.6 4.6e-25 87.3 0.0 4.4 4 1 1 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP15097.1 - 1e-16 61.3 0.1 2.2e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CEP15097.1 - 1.2e-08 34.5 14.4 1.2e-08 34.5 14.4 3.3 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_18 PF13238.6 CEP15097.1 - 9.6e-05 22.9 0.0 0.0026 18.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CEP15097.1 - 0.00011 22.1 0.4 0.0022 17.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CEP15097.1 - 0.00016 21.6 0.1 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEP15097.1 - 0.00059 20.3 0.0 0.026 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CEP15097.1 - 0.0039 17.4 0.0 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CEP15097.1 - 0.0047 16.6 0.3 0.021 14.6 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CEP15097.1 - 0.0066 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CEP15097.1 - 0.047 13.4 0.2 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP15097.1 - 0.055 13.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEP15097.1 - 0.076 12.6 0.1 0.76 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CEP15097.1 - 0.097 12.9 0.2 2 8.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain DnaB_C PF03796.15 CEP15097.1 - 0.13 11.6 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PDR_assoc PF08370.11 CEP15097.1 - 0.3 10.9 6.7 5 6.9 1.0 3.1 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_23 PF13476.6 CEP15097.1 - 5.6 7.4 8.5 0.51 10.8 0.2 2.8 3 0 0 3 3 3 0 AAA domain RBD-FIP PF09457.10 CEP15098.1 - 0.027 14.4 5.3 1.5 8.8 1.2 3.8 4 0 0 4 4 4 0 FIP domain Sec34 PF04136.15 CEP15098.1 - 0.055 13.4 11.2 0.083 12.8 9.6 2.0 1 1 1 2 2 2 0 Sec34-like family Tup_N PF08581.10 CEP15098.1 - 0.36 11.1 13.6 2.5 8.4 2.9 2.5 1 1 1 2 2 2 0 Tup N-terminal GvpL_GvpF PF06386.11 CEP15098.1 - 0.41 10.5 5.4 0.51 10.2 4.3 1.8 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ATG16 PF08614.11 CEP15098.1 - 0.81 9.9 21.2 3 8.0 20.9 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF349 PF03993.12 CEP15098.1 - 3.6 7.9 13.4 9 6.7 7.0 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) CALM_bind PF16025.5 CEP15098.1 - 7.6 7.1 16.9 0.29 11.6 2.9 3.4 1 1 1 2 2 2 0 Calcium-dependent calmodulin binding DUF4239 PF14023.6 CEP15098.1 - 8.8 6.0 6.4 16 5.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Rieske PF00355.26 CEP15099.1 - 1.7e-07 31.1 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain IMUP PF15761.5 CEP15099.1 - 2.4e-05 25.0 5.7 2.4e-05 25.0 5.7 2.9 3 0 0 3 3 2 1 Immortalisation up-regulated protein SR-25 PF10500.9 CEP15099.1 - 2.6e-05 23.9 28.9 0.00052 19.7 7.2 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 CEP15099.1 - 0.00032 20.2 14.7 0.0004 19.8 14.7 1.1 1 0 0 1 1 1 1 BUD22 Peroxin-3 PF04882.12 CEP15099.1 - 0.032 13.2 10.6 0.056 12.4 10.6 1.3 1 0 0 1 1 1 0 Peroxin-3 DUF4834 PF16118.5 CEP15099.1 - 0.58 11.2 8.3 7.2 7.6 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rtf2 PF04641.12 CEP15099.1 - 0.82 9.0 16.9 0.029 13.7 5.8 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Peroxin-13_N PF04088.13 CEP15099.1 - 0.93 9.8 9.7 0.46 10.8 3.0 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region U3_snoRNA_assoc PF08297.11 CEP15099.1 - 1.3 9.7 14.8 1.4 9.6 9.3 2.6 2 0 0 2 2 2 0 U3 snoRNA associated Peptidase_S49_N PF08496.10 CEP15099.1 - 1.9 8.5 11.8 0.16 12.0 5.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4519 PF15012.6 CEP15099.1 - 1.9 8.7 12.4 4.4 7.5 12.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) EOS1 PF12326.8 CEP15099.1 - 2.2 8.2 5.4 4.9 7.0 0.6 2.2 2 0 0 2 2 2 0 N-glycosylation protein Connexin PF00029.19 CEP15099.1 - 2.5 7.8 6.2 2.6 7.8 1.7 2.2 2 0 0 2 2 2 0 Connexin PRC2_HTH_1 PF18118.1 CEP15099.1 - 6.9 7.5 11.6 2 9.3 1.8 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain EIIBC-GUT_N PF03612.14 CEP15099.1 - 7.3 6.3 8.1 4.6 6.9 2.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus IGR PF09597.10 CEP15100.1 - 1.1e-25 89.5 0.1 1.4e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 IGR protein motif MatE PF01554.18 CEP15101.1 - 6.9e-51 172.1 22.9 2.1e-27 95.7 7.8 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CEP15101.1 - 2.6e-06 27.5 17.1 2.6e-06 27.5 17.1 3.5 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain zf-LITAF-like PF10601.9 CEP15102.1 - 0.092 13.0 0.6 0.092 13.0 0.6 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain SNARE_assoc PF09335.11 CEP15103.1 - 2.3e-13 50.7 2.5 2.3e-13 50.7 2.5 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein Saf_2TM PF18303.1 CEP15103.1 - 0.17 11.4 4.2 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4212 PF13937.6 CEP15103.1 - 9.1 6.7 13.7 0.27 11.6 2.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Nucleoporin_N PF08801.11 CEP15104.1 - 4.1e-62 210.3 0.5 9.7e-62 209.1 0.5 1.6 1 0 0 1 1 1 1 Nup133 N terminal like HA2 PF04408.23 CEP15104.1 - 1.1e-19 70.6 0.0 2.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEP15104.1 - 1.9e-19 69.8 0.0 5.5e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Nucleoporin_C PF03177.14 CEP15104.1 - 7.9e-18 64.5 3.2 1.3e-15 57.2 0.6 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Helicase_C PF00271.31 CEP15104.1 - 1.3e-12 48.0 0.0 4.7e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP15104.1 - 2.9e-07 30.4 0.2 7.2e-07 29.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CEP15104.1 - 0.0014 19.0 0.1 0.0034 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP15104.1 - 0.0015 18.8 0.1 0.0067 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEP15104.1 - 0.0054 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CEP15104.1 - 0.068 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain BRCA-2_OB3 PF09104.10 CEP15104.1 - 0.082 12.6 0.0 0.39 10.4 0.0 2.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 WD40 PF00400.32 CEP15105.1 - 8.9e-46 153.0 18.0 3.2e-08 34.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15105.1 - 6.5e-18 64.8 6.4 0.0006 20.1 0.3 6.6 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP15105.1 - 3.4e-09 36.9 3.6 0.00061 19.7 0.3 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEP15105.1 - 0.00078 18.9 0.0 0.65 9.3 0.0 3.0 1 1 3 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CEP15105.1 - 0.021 13.8 0.6 2.7 6.9 0.1 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 CEP15105.1 - 0.051 12.6 0.0 6.6 5.7 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Glucosamine_iso PF01182.20 CEP15106.1 - 5.4e-18 65.7 0.0 8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PDEase_I PF00233.19 CEP15107.1 - 1.5e-74 250.8 0.3 2.7e-74 249.9 0.3 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 CEP15107.1 - 0.033 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 Response regulator receiver domain GPS2_interact PF15784.5 CEP15107.1 - 0.87 10.1 3.4 5.3 7.6 0.3 2.4 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain UDG PF03167.19 CEP15109.1 - 2.6e-16 60.0 0.0 3.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RNA_pol_Rpc82 PF05645.13 CEP15110.1 - 7.5e-23 81.6 0.8 1.6e-22 80.5 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CEP15110.1 - 1.7e-21 76.0 0.3 1.9e-16 59.9 0.1 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CEP15110.1 - 1.4e-06 28.1 2.1 0.0042 16.9 0.0 4.0 4 0 0 4 4 4 2 TFIIE alpha subunit TrmB PF01978.19 CEP15110.1 - 0.001 18.9 0.0 1.5 8.8 0.0 4.0 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB Coatomer_E PF04733.14 CEP15112.1 - 1.2e-81 274.3 7.3 1.4e-81 274.1 7.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 CEP15112.1 - 4.2e-08 33.3 4.6 0.0089 16.2 0.5 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CEP15112.1 - 1.4e-06 28.7 11.7 0.05 14.1 0.1 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP15112.1 - 6.2e-06 26.4 6.1 0.00065 19.9 0.6 3.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 CEP15112.1 - 5.5e-05 23.4 5.9 0.019 15.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP15112.1 - 0.00015 22.3 6.7 0.11 13.2 0.1 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat RPN7 PF10602.9 CEP15112.1 - 0.00041 20.1 0.5 0.0014 18.3 0.5 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 SRP_TPR_like PF17004.5 CEP15112.1 - 0.0024 17.9 2.1 0.25 11.3 0.1 2.6 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_14 PF13428.6 CEP15112.1 - 0.0025 18.5 5.5 0.81 10.7 0.3 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP15112.1 - 0.019 14.8 0.9 2.8 7.9 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP15112.1 - 0.025 14.0 8.1 0.092 12.1 7.0 2.2 1 1 0 2 2 2 0 MalT-like TPR region DUF5588 PF17826.1 CEP15112.1 - 0.028 13.3 1.0 0.36 9.7 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5588) TPR_5 PF12688.7 CEP15112.1 - 0.13 12.5 1.9 7.7 6.8 0.2 2.7 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_2 PF07719.17 CEP15112.1 - 0.14 12.3 10.2 0.21 11.8 0.1 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CEP15112.1 - 0.15 12.5 2.3 2.6 8.4 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CEP15112.1 - 0.35 10.6 7.6 0.082 12.6 2.5 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain HemY_N PF07219.13 CEP15112.1 - 0.61 10.3 3.5 5.1 7.4 0.1 2.9 3 1 0 3 3 3 0 HemY protein N-terminus TPR_10 PF13374.6 CEP15112.1 - 2.5 8.1 6.4 19 5.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Snf7 PF03357.21 CEP15114.1 - 2.4e-36 124.9 22.4 3.3e-36 124.5 22.4 1.1 1 0 0 1 1 1 1 Snf7 GlnE PF03710.15 CEP15114.1 - 0.3 10.5 4.4 0.075 12.4 0.4 1.8 1 1 1 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase MtrG PF04210.13 CEP15114.1 - 0.37 10.7 4.4 7.8 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PTR2 PF00854.21 CEP15115.1 - 7.5e-92 308.2 9.2 1.3e-91 307.4 9.2 1.4 1 0 0 1 1 1 1 POT family Translin PF01997.16 CEP15116.1 - 9.7e-45 153.1 0.2 1.1e-44 152.9 0.2 1.0 1 0 0 1 1 1 1 Translin family Glyco_hydro_53 PF07745.13 CEP15116.1 - 9.4e-05 21.5 0.4 0.00029 20.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 CLASP_N PF12348.8 CEP15116.1 - 0.043 13.4 0.0 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 CLASP N terminal M157 PF11624.8 CEP15116.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 Allantoicase PF03561.15 CEP15117.1 - 4.2e-76 253.8 0.0 7.6e-39 133.0 0.0 2.3 2 1 0 2 2 2 2 Allantoicase repeat DUF953 PF06110.11 CEP15118.1 - 5.6e-24 84.0 0.0 6.2e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 CEP15118.1 - 0.0027 17.6 0.1 0.0077 16.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CEP15118.1 - 0.009 16.2 0.0 0.028 14.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CEP15118.1 - 0.017 14.9 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin RVT_1 PF00078.27 CEP15119.1 - 7.7e-36 123.7 0.0 1.4e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP15119.1 - 1.9e-08 34.9 2.3 4.7e-08 33.6 0.6 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 CEP15119.1 - 6.9e-06 25.9 0.4 6.9e-06 25.9 0.4 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP15119.1 - 0.0025 17.8 17.2 0.0037 17.3 3.0 2.9 2 0 0 2 2 2 2 Zinc knuckle Cwf_Cwc_15 PF04889.12 CEP15119.1 - 0.85 9.3 8.2 1.6 8.4 8.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DnaJ_CXXCXGXG PF00684.19 CEP15119.1 - 5.4 7.5 7.0 22 5.5 6.5 2.2 2 0 0 2 2 2 0 DnaJ central domain Cofilin_ADF PF00241.20 CEP15120.1 - 3.1e-26 91.5 0.2 3.5e-26 91.4 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF815 PF05673.13 CEP15120.1 - 0.08 12.1 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UCH PF00443.29 CEP15121.1 - 6.2e-40 137.3 0.1 8.4e-40 136.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEP15121.1 - 2.9e-13 49.9 0.4 6.5e-13 48.8 0.4 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CEP15121.1 - 1.4e-10 41.3 0.6 2e-09 37.5 0.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Forkhead PF00250.18 CEP15122.1 - 2e-37 127.3 0.8 3.7e-37 126.4 0.2 1.8 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CEP15122.1 - 8.5e-13 48.5 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CEP15122.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 FHA domain adh_short PF00106.25 CEP15123.1 - 2.9e-26 92.1 0.1 3.6e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP15123.1 - 8.7e-15 54.9 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP15123.1 - 9e-05 22.5 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP15123.1 - 0.0021 17.5 0.1 0.0026 17.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Herpes_UL49_5 PF05702.11 CEP15123.1 - 0.55 10.3 2.2 1 9.5 1.3 1.8 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Cation_ATPase_C PF00689.21 CEP15125.1 - 6.5e-24 84.6 10.8 5.1e-23 81.7 4.2 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP15125.1 - 1.1e-17 63.9 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP15125.1 - 4.9e-17 62.9 0.1 6.6e-14 52.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP15125.1 - 1.2e-16 60.8 10.6 1.3e-16 60.7 0.9 3.3 2 1 1 3 3 3 2 E1-E2 ATPase HAD PF12710.7 CEP15125.1 - 0.015 15.7 0.0 0.047 14.1 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP15125.1 - 0.017 14.9 2.1 0.043 13.5 0.9 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 CEP15125.1 - 3.7 8.1 4.6 10 6.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) E1-E2_ATPase PF00122.20 CEP15126.1 - 2.2e-20 72.9 2.7 3.4e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CEP15126.1 - 1.3e-15 56.8 0.0 2.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Raffinose_syn PF05691.12 CEP15127.1 - 1.6e-51 175.1 10.9 3.6e-39 134.2 5.5 3.8 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 NEMP PF10225.9 CEP15128.1 - 0.019 14.7 1.0 0.032 13.9 1.0 1.4 1 0 0 1 1 1 0 NEMP family eIF-3_zeta PF05091.12 CEP15128.1 - 0.064 12.2 4.9 0.11 11.4 4.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 CEP15128.1 - 0.096 13.7 5.2 0.049 14.6 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 CEP15128.1 - 0.11 12.0 27.2 0.24 11.0 27.2 1.5 1 0 0 1 1 1 0 Spt20 family LRR_6 PF13516.6 CEP15128.1 - 0.12 12.5 2.1 6.5 7.1 0.0 3.9 5 0 0 5 5 5 0 Leucine Rich repeat EPL1 PF10513.9 CEP15128.1 - 0.4 11.1 8.4 0.07 13.5 4.2 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF702 PF05142.12 CEP15128.1 - 0.48 10.9 6.4 1.1 9.8 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Pex14_N PF04695.13 CEP15128.1 - 0.53 10.9 18.3 0.92 10.2 18.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CEP15128.1 - 0.6 8.8 6.5 0.97 8.1 6.5 1.3 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CEP15128.1 - 0.7 8.6 6.2 1.2 7.9 6.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 CEP15128.1 - 2.4 6.3 17.3 3.3 5.9 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 CEP15128.1 - 2.5 8.0 10.5 4.4 7.2 10.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 CEP15128.1 - 3.4 7.0 8.5 0.22 10.9 3.4 1.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4770 PF15994.5 CEP15128.1 - 3.5 7.8 12.7 6.3 7.0 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF1699 PF08004.11 CEP15128.1 - 5.3 6.7 9.5 3.3 7.4 0.2 3.3 4 1 0 4 4 3 0 Protein of unknown function (DUF1699) TFIIA PF03153.13 CEP15128.1 - 7.7 6.4 33.4 0.2 11.6 24.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit COX6B PF02297.17 CEP15129.1 - 3.2e-20 72.2 6.9 3.9e-20 71.9 6.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 CEP15129.1 - 0.0023 17.8 0.1 0.003 17.5 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like C-terminal domain DUF2015 PF09435.10 CEP15132.1 - 0.18 11.7 2.2 0.36 10.7 1.6 1.7 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2015) Metallophos PF00149.28 CEP15133.1 - 5.6e-37 128.2 0.1 9.8e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP15133.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Zds_C PF08632.10 CEP15134.1 - 3.6e-25 87.5 3.3 6e-25 86.8 1.2 2.4 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Cation_ATPase_C PF00689.21 CEP15135.1 - 7.3e-10 38.8 17.9 7.3e-10 38.8 17.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Ribosomal_L44 PF00935.19 CEP15135.1 - 0.65 10.5 6.3 0.06 13.8 0.8 2.0 2 0 0 2 2 2 0 Ribosomal protein L44 E1-E2_ATPase PF00122.20 CEP15135.1 - 3 7.4 11.8 0.99 8.9 0.1 3.4 4 0 0 4 4 4 0 E1-E2 ATPase Pro_isomerase PF00160.21 CEP15136.1 - 4.1e-47 160.4 0.0 4.5e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 CEP15136.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) Ligase_CoA PF00549.19 CEP15136.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 CoA-ligase RRM_1 PF00076.22 CEP15137.1 - 1.2e-31 108.4 0.1 4.5e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP15137.1 - 3.1e-07 30.3 0.4 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF5427 PF10310.9 CEP15137.1 - 0.0023 17.0 17.0 0.0023 17.0 17.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5427) RRM_Rrp7 PF17799.1 CEP15137.1 - 0.036 13.9 1.6 4.9 6.9 0.0 3.3 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain Lys-AminoMut_A PF09043.11 CEP15137.1 - 0.41 9.1 3.7 0.58 8.5 3.7 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit Vpu PF00558.19 CEP15137.1 - 0.49 10.2 2.3 1.4 8.7 2.3 1.8 1 0 0 1 1 1 0 Vpu protein zf-C2H2_jaz PF12171.8 CEP15138.1 - 0.00042 20.5 0.0 0.00087 19.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP15138.1 - 0.00062 20.1 0.3 0.0011 19.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SelR PF01641.18 CEP15138.1 - 0.042 13.9 0.3 0.098 12.7 0.3 1.6 1 0 0 1 1 1 0 SelR domain zf-C2H2_2 PF12756.7 CEP15138.1 - 0.082 13.3 1.5 0.22 11.9 1.5 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 CEP15138.1 - 0.32 11.5 5.6 0.069 13.6 1.1 2.2 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Methyltransf_4 PF02390.17 CEP15138.1 - 0.74 9.3 5.0 0.11 11.9 0.9 1.7 2 0 0 2 2 2 0 Putative methyltransferase CENP-O PF09496.10 CEP15138.1 - 2.9 7.8 11.5 0.86 9.5 2.9 2.3 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component B56 PF01603.20 CEP15139.1 - 4.3e-178 592.5 12.0 1.7e-118 396.2 2.3 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Myb_DNA-bind_7 PF15963.5 CEP15139.1 - 0.0031 17.4 0.6 0.0096 15.8 0.6 1.8 1 0 0 1 1 1 1 Myb DNA-binding like HTH_Tnp_1_2 PF13022.6 CEP15139.1 - 0.044 13.9 0.7 2.1 8.5 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase PfkB PF00294.24 CEP15140.1 - 9.8e-28 97.3 0.3 7.2e-27 94.5 0.3 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pup_ligase PF03136.15 CEP15140.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein DFP PF04127.15 CEP15140.1 - 0.035 14.0 0.3 0.09 12.6 0.3 1.7 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ldh_1_C PF02866.18 CEP15141.1 - 1.7e-47 161.5 0.2 4.2e-47 160.2 0.2 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CEP15141.1 - 1.7e-45 154.5 0.1 2.9e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CEP15141.1 - 1.6e-05 24.0 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CEP15141.1 - 0.0019 18.6 0.3 0.0057 17.1 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CEP15141.1 - 0.0026 17.9 0.0 0.0075 16.4 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.16 CEP15141.1 - 0.019 14.5 0.1 4 6.9 0.1 2.5 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.6 CEP15141.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Cyanate_lyase PF02560.14 CEP15142.1 - 6.1e-30 102.9 0.1 9.1e-30 102.3 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 CEP15142.1 - 0.00019 21.4 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CEP15142.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Homeodomain PF00046.29 CEP15142.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain Sugar_tr PF00083.24 CEP15143.1 - 6.9e-130 433.9 24.7 8e-130 433.7 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP15143.1 - 1.7e-23 83.2 41.4 1.6e-18 66.8 13.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2655 PF10848.8 CEP15143.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) FAT PF02259.23 CEP15144.1 - 1.6e-66 224.9 11.7 5.5e-66 223.1 11.7 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CEP15144.1 - 2.5e-30 106.1 1.4 4.4e-30 105.3 0.3 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEP15144.1 - 2.4e-05 24.1 0.9 6.4e-05 22.7 0.9 1.7 1 0 0 1 1 1 1 FATC domain GSDH PF07995.11 CEP15144.1 - 0.03 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase RasGEF_N_2 PF14663.6 CEP15144.1 - 0.048 14.1 0.9 2.1 8.8 0.1 3.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sec7_N PF12783.7 CEP15144.1 - 0.06 13.2 18.8 0.36 10.7 0.2 7.0 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RIX1 PF08167.12 CEP15144.1 - 0.26 11.0 5.3 3.9 7.2 0.0 5.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis RVT_1 PF00078.27 CEP15145.1 - 1.6e-08 34.4 0.1 5.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1180 PF06679.12 CEP15146.1 - 0.12 12.8 2.5 3.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DKCLD PF08068.12 CEP15148.1 - 2.9e-35 120.1 0.2 5.2e-33 112.9 0.2 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CEP15148.1 - 3e-23 81.7 0.4 5.8e-23 80.8 0.4 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 CEP15148.1 - 7.9e-23 81.5 0.2 4.5e-20 72.5 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CEP15148.1 - 2.5e-19 69.0 0.9 4.8e-19 68.1 0.9 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CEP15148.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain RNA_polI_A34 PF08208.11 CEP15148.1 - 0.83 9.7 21.0 1.2 9.1 21.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TrkH PF02386.16 CEP15149.1 - 1.1e-87 294.6 9.7 1.1e-87 294.6 9.7 2.0 2 0 0 2 2 2 2 Cation transport protein ZZ PF00569.17 CEP15150.1 - 6.1e-25 86.8 40.0 1.5e-09 37.5 6.6 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 CEP15150.1 - 3.9e-21 75.7 0.0 1.8e-20 73.6 0.0 2.2 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 CEP15150.1 - 1.2e-06 28.7 33.5 0.013 15.8 6.2 3.6 3 0 0 3 3 3 3 C1 domain PB1 PF00564.24 CEP15150.1 - 0.11 12.5 0.9 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 PB1 domain DUF2529 PF10740.9 CEP15150.1 - 0.4 10.3 2.3 1.5 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) RRP7 PF12923.7 CEP15150.1 - 1.1 9.4 7.9 0.78 9.9 0.1 2.9 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TT_ORF1 PF02956.14 CEP15150.1 - 8.6 4.9 8.1 2.6 6.6 3.4 2.2 2 0 0 2 2 2 0 TT viral orf 1 PIP5K PF01504.18 CEP15151.1 - 7.3e-97 323.9 1.8 1.4e-96 322.9 1.8 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2617 PF10936.8 CEP15151.1 - 0.25 11.4 2.5 0.4 10.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2617 Glyco_hydro_3 PF00933.21 CEP15152.1 - 4.3e-89 299.0 0.1 6.1e-89 298.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 CEP15152.1 - 3.9e-18 65.8 0.0 1.9e-10 41.0 0.0 3.3 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP15152.1 - 1.6e-16 60.4 0.1 4.3e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEP15152.1 - 9.5e-14 51.6 0.5 1.2e-05 25.4 0.0 4.0 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP15152.1 - 5.4e-13 49.0 0.0 1.8e-09 37.6 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP15152.1 - 9.4e-06 25.7 0.0 0.033 14.3 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.10 CEP15152.1 - 1.7e-05 24.7 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.7 CEP15152.1 - 3e-05 24.2 0.0 9.6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CEP15152.1 - 0.00052 20.2 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 CEP15152.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF1598 PF07643.11 CEP15152.1 - 0.055 13.7 0.0 23 5.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1598) OrfB_Zn_ribbon PF07282.11 CEP15153.1 - 0.015 15.2 0.1 0.21 11.5 0.0 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain HTH_5 PF01022.20 CEP15153.1 - 0.16 11.8 0.2 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 CEP15153.1 - 0.23 11.0 0.8 1.8 8.2 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Sec2p PF06428.11 CEP15154.1 - 2.2e-22 78.8 18.9 2.2e-22 78.8 18.9 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.11 CEP15154.1 - 0.015 14.2 23.2 0.021 13.7 23.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) hDGE_amylase PF14701.6 CEP15154.1 - 0.26 10.3 14.9 0.36 9.9 14.9 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain FAA_hydro_N_2 PF18288.1 CEP15154.1 - 4.3 7.8 5.8 2.4 8.7 0.1 3.2 1 1 3 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 DUF836 PF05768.14 CEP15154.1 - 5.1 7.6 8.4 17 5.9 8.4 2.0 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Velvet PF11754.8 CEP15155.1 - 6.7e-43 147.4 0.3 9.2e-23 81.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor DEAD PF00270.29 CEP15156.1 - 4.5e-41 140.5 0.3 7.9e-41 139.7 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S19 PF00203.21 CEP15156.1 - 1.8e-32 111.0 0.5 6.6e-32 109.2 0.5 2.1 1 0 0 1 1 1 1 Ribosomal protein S19 Helicase_C PF00271.31 CEP15156.1 - 7.2e-31 106.8 0.2 3.1e-29 101.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP15156.1 - 9.5e-08 32.2 0.2 2.9e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CEP15156.1 - 0.18 11.7 1.4 0.32 10.8 0.1 2.0 2 0 0 2 2 2 0 Helicase DnaI_N PF07319.11 CEP15156.1 - 0.23 12.2 2.4 14 6.4 0.3 3.5 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Usp PF00582.26 CEP15158.1 - 4.6e-08 33.7 0.0 6.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4165 PF13752.6 CEP15158.1 - 0.0067 16.4 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4165) DUF2015 PF09435.10 CEP15159.1 - 8e-32 109.4 0.0 9.7e-32 109.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF3301 PF11743.8 CEP15159.1 - 0.069 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) MLANA PF14991.6 CEP15159.1 - 0.17 12.2 0.8 0.26 11.6 0.8 1.7 1 1 0 1 1 1 0 Protein melan-A CTC1 PF15489.6 CEP15160.1 - 4.2e-17 61.0 0.2 2.8e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 Glyco_transf_15 PF01793.16 CEP15161.1 - 3.4e-98 328.9 11.8 5e-98 328.3 11.8 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3097 PF11296.8 CEP15161.1 - 0.027 13.7 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) PAP_central PF04928.17 CEP15162.1 - 7.2e-109 362.5 0.0 9.5e-109 362.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEP15162.1 - 3.3e-40 137.5 0.0 5.6e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEP15162.1 - 4e-10 39.9 0.0 8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CEP15162.1 - 0.028 14.2 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Ank_2 PF12796.7 CEP15163.1 - 0.02 15.5 0.0 0.059 14.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) SPT16 PF08644.11 CEP15163.1 - 1.2 9.4 0.0 1.2 9.4 0.0 4.0 3 1 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) TPR_1 PF00515.28 CEP15164.1 - 2.6e-46 153.6 9.8 8.7e-08 31.7 0.0 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP15164.1 - 8.8e-45 147.2 2.5 1e-06 28.4 0.0 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 CEP15164.1 - 2.1e-33 111.7 11.1 0.00059 19.8 0.0 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 CEP15164.1 - 7.6e-25 87.3 0.1 2e-06 28.3 0.0 6.5 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP15164.1 - 6.4e-22 77.0 6.3 2.4e-05 23.9 0.1 8.7 4 3 5 9 9 9 4 TPR repeat TPR_12 PF13424.6 CEP15164.1 - 7.2e-22 77.5 10.6 7.4e-06 26.2 0.1 8.0 4 4 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEP15164.1 - 5.4e-21 73.4 5.4 9.2e-05 22.6 0.0 9.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEP15164.1 - 2.1e-20 71.6 0.9 0.014 16.1 0.1 9.5 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 CEP15164.1 - 2.1e-19 69.8 5.6 4e-05 24.0 0.2 7.0 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 CEP15164.1 - 1.1e-18 65.8 2.3 0.051 13.6 0.0 9.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 CEP15164.1 - 1.2e-11 44.5 0.6 0.045 13.9 0.0 5.1 4 2 1 5 5 4 4 Tetratricopeptide repeat NARP1 PF12569.8 CEP15164.1 - 5.3e-10 38.8 0.3 0.0052 15.8 0.0 3.7 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CEP15164.1 - 2.7e-09 36.6 7.7 0.03 14.2 0.1 7.6 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEP15164.1 - 3.2e-09 36.4 0.3 0.025 13.8 0.1 5.2 2 2 3 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP15164.1 - 6.5e-09 35.9 9.6 0.011 16.0 0.1 4.8 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CEP15164.1 - 4.2e-08 33.3 5.5 9.9 7.0 0.0 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat BTAD PF03704.17 CEP15164.1 - 1.7e-05 25.3 0.6 1.3 9.4 0.1 3.9 3 2 1 4 4 4 2 Bacterial transcriptional activator domain MIT PF04212.18 CEP15164.1 - 7.5e-05 22.7 9.0 4.4 7.5 0.0 7.1 8 0 0 8 8 7 1 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 CEP15164.1 - 9.3e-05 22.0 0.8 0.87 8.9 0.1 5.2 3 1 1 5 5 5 1 MalT-like TPR region TPR_5 PF12688.7 CEP15164.1 - 0.00012 22.3 0.5 0.14 12.4 0.1 4.0 2 2 1 3 3 3 1 Tetratrico peptide repeat TPR_21 PF09976.9 CEP15164.1 - 0.0015 18.3 4.4 4.5 6.9 0.0 4.3 2 1 1 5 5 5 1 Tetratricopeptide repeat-like domain Clathrin PF00637.20 CEP15164.1 - 0.0085 16.0 0.2 0.51 10.2 0.0 3.4 2 1 1 3 3 3 1 Region in Clathrin and VPS ArsR PF09824.9 CEP15164.1 - 0.037 13.6 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 ArsR transcriptional regulator TPR_4 PF07721.14 CEP15164.1 - 0.064 13.9 0.0 2.2e+02 3.0 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat 14-3-3 PF00244.20 CEP15164.1 - 0.2 11.1 2.8 0.39 10.2 0.0 2.8 3 1 1 4 4 4 0 14-3-3 protein SNAP PF14938.6 CEP15164.1 - 4.5 6.6 13.0 3.8 6.8 1.2 4.3 2 2 2 4 4 4 0 Soluble NSF attachment protein, SNAP NAP PF00956.18 CEP15165.1 - 6.8e-17 61.5 5.6 6.7e-13 48.4 1.3 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) RNF220 PF15926.5 CEP15165.1 - 0.02 14.5 4.0 0.029 14.0 4.0 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 DTHCT PF08070.11 CEP15165.1 - 0.11 13.2 0.9 0.11 13.2 0.9 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Ribosomal_L18 PF17135.4 CEP15166.1 - 2.9e-88 294.2 5.1 3.4e-88 294.0 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CEP15166.1 - 0.0012 19.6 0.3 0.0027 18.4 0.3 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Spindle_Spc25 PF08234.12 CEP15167.1 - 1.5e-17 63.6 2.2 2.1e-17 63.1 0.2 2.4 2 1 1 3 3 3 1 Chromosome segregation protein Spc25 FapA PF03961.13 CEP15167.1 - 0.063 11.9 17.9 0.091 11.3 17.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 CEP15167.1 - 0.29 11.4 24.8 0.2 11.9 12.9 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 CEP15167.1 - 0.32 11.1 15.3 0.036 14.1 8.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 CEP15167.1 - 0.57 10.5 28.9 0.055 13.8 12.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CEP15167.1 - 2 7.7 14.5 2.9 7.2 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 CEP15167.1 - 2.2 7.8 15.7 2.8 7.4 15.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CEP15167.1 - 2.6 7.0 25.1 3.5 6.6 25.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CEP15167.1 - 2.8 5.8 13.4 3 5.7 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 CEP15167.1 - 2.8 6.7 16.7 3.6 6.3 16.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CorA PF01544.18 CEP15167.1 - 3.5 6.9 12.0 4.9 6.4 12.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mcp5_PH PF12814.7 CEP15168.1 - 5.1e-20 71.8 1.2 5.1e-20 71.8 1.2 2.4 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF641 PF04859.12 CEP15168.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.9 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Fungal_TACC PF12709.7 CEP15168.1 - 2.4 8.7 29.1 0.93 10.0 2.5 5.1 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-F_leu_zip PF10473.9 CEP15168.1 - 3.4 7.7 31.9 0.16 12.0 2.2 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 USP7_ICP0_bdg PF12436.8 CEP15169.1 - 2.8e-61 206.9 0.1 8.4e-61 205.3 0.1 1.9 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CEP15169.1 - 5.1e-51 173.3 3.6 1.8e-49 168.3 0.5 2.9 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 CEP15169.1 - 1.7e-47 162.1 0.2 3e-47 161.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP15169.1 - 1.1e-23 84.3 0.0 2.4e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CEP15169.1 - 1.5e-08 34.8 0.7 2.2e-07 31.0 0.0 3.0 2 1 1 3 3 3 1 MATH domain UQ_con PF00179.26 CEP15170.1 - 3.2e-22 78.7 0.0 7.1e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme EMP24_GP25L PF01105.24 CEP15171.1 - 1e-45 155.9 0.4 1.2e-45 155.6 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CEP15171.1 - 0.017 13.3 1.4 0.021 13.0 1.4 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ZapB PF06005.12 CEP15171.1 - 0.037 14.5 0.4 0.069 13.6 0.4 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Aminotran_5 PF00266.19 CEP15172.1 - 3.4e-23 82.2 0.1 4.4e-23 81.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEP15172.1 - 0.00026 20.3 0.0 0.00035 19.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zf-LSD1 PF06943.12 CEP15172.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 LSD1 zinc finger Ion_trans PF00520.31 CEP15173.1 - 1.1e-11 44.4 16.1 1.1e-11 44.4 16.1 1.8 1 1 0 1 1 1 1 Ion transport protein Big_3_3 PF13750.6 CEP15174.1 - 0.079 12.6 1.3 0.12 12.0 1.3 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Chromo PF00385.24 CEP15175.1 - 1.5e-10 40.9 0.2 3.2e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CEP15175.1 - 1.1e-09 38.5 0.1 4.9e-09 36.4 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.8 CEP15175.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain AAA_16 PF13191.6 CEP15176.1 - 4.5e-10 40.2 0.0 2.3e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP15176.1 - 0.00037 20.8 0.1 0.045 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 CEP15176.1 - 0.035 12.9 0.1 0.067 12.0 0.1 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 CEP15176.1 - 0.077 13.4 0.0 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Guanylate_cyc PF00211.20 CEP15176.1 - 0.088 12.4 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Sigma54_activat PF00158.26 CEP15176.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AA_permease PF00324.21 CEP15177.1 - 4.3e-128 427.9 41.3 5.4e-128 427.6 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP15177.1 - 2.4e-40 138.7 43.2 3.1e-40 138.3 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease Rad21_Rec8_N PF04825.13 CEP15178.1 - 2.7e-32 111.2 0.1 4.9e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CEP15178.1 - 6.7e-14 50.9 0.0 1.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CEP15178.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA G-alpha PF00503.20 CEP15179.1 - 4.5e-120 401.0 5.3 5.3e-120 400.8 5.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP15179.1 - 1.5e-15 57.1 1.3 2e-10 40.4 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP15179.1 - 0.0012 18.3 3.9 0.025 13.9 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP15179.1 - 0.053 13.7 2.2 1.4 9.2 0.1 2.8 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CEP15179.1 - 0.071 12.4 0.0 0.34 10.2 0.0 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CEP15179.1 - 0.073 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC4_2 PF13923.6 CEP15180.1 - 6.2e-12 45.2 8.8 6.2e-12 45.2 8.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP15180.1 - 5.1e-09 35.9 10.8 5.1e-09 35.9 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP15180.1 - 2.1e-08 34.1 3.7 2.1e-08 34.1 3.7 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP15180.1 - 3.5e-08 33.3 8.9 3.5e-08 33.3 8.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CEP15180.1 - 8e-08 32.1 2.9 8e-08 32.1 2.9 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CEP15180.1 - 3.7e-07 29.9 7.3 3.7e-07 29.9 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP15180.1 - 2.1e-06 27.9 18.9 2.2e-06 27.9 9.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CEP15180.1 - 8.5e-05 22.8 3.8 8.5e-05 22.8 3.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CEP15180.1 - 0.00011 22.0 14.4 0.0082 16.0 10.0 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP15180.1 - 0.0035 17.4 1.5 0.0035 17.4 1.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEP15180.1 - 0.0043 16.8 14.6 0.031 14.1 2.3 3.3 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CEP15180.1 - 0.018 15.2 7.7 0.018 15.2 7.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF5318 PF17249.2 CEP15180.1 - 0.03 14.1 0.0 3.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5318) U-box PF04564.15 CEP15180.1 - 0.061 13.5 3.4 0.58 10.4 0.0 3.3 4 1 1 5 5 3 0 U-box domain zf-Nse PF11789.8 CEP15180.1 - 0.45 10.4 10.8 0.31 10.9 5.1 2.7 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit Zn-C2H2_12 PF18112.1 CEP15180.1 - 0.49 10.9 11.0 0.91 10.1 0.1 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_5 PF17121.5 CEP15180.1 - 1.2 9.1 13.2 6.2 6.8 3.9 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CEP15180.1 - 1.2 9.3 10.2 0.058 13.5 3.8 2.1 3 0 0 3 3 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 CEP15180.1 - 4.2 7.4 11.6 1.8 8.6 4.2 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-C2H2_4 PF13894.6 CEP15180.1 - 5.3 8.1 11.8 6.6 7.9 1.0 4.0 4 0 0 4 4 3 0 C2H2-type zinc finger YacG PF03884.14 CEP15180.1 - 6.1 6.7 8.8 13 5.6 0.4 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-Di19 PF05605.12 CEP15180.1 - 9.8 6.6 13.7 22 5.5 1.0 3.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4203 PF13886.6 CEP15181.1 - 1.6e-31 109.6 32.1 1.6e-31 109.6 32.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Proton_antipo_N PF00662.20 CEP15181.1 - 4.7 7.4 9.0 1.9 8.6 0.6 3.3 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus HMA PF00403.26 CEP15182.1 - 6.7e-72 237.9 3.0 9.1e-12 45.3 0.0 7.6 7 0 0 7 7 7 7 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CEP15182.1 - 1.8e-48 164.5 2.7 1.8e-48 164.5 2.7 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CEP15182.1 - 7e-31 108.1 0.0 2.2e-30 106.5 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP15182.1 - 0.00026 20.8 0.2 0.0032 17.3 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP15182.1 - 0.00055 20.4 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2200 PF09966.9 CEP15182.1 - 9.2 6.5 6.6 36 4.5 0.0 4.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2200) F-box-like PF12937.7 CEP15183.1 - 2.4e-07 30.5 1.1 7.7e-07 28.9 1.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP15183.1 - 0.0023 17.8 0.0 0.0078 16.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain Kinesin PF00225.23 CEP15184.1 - 3.4e-110 368.1 6.4 1.3e-62 211.6 0.0 3.8 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CEP15184.1 - 1.5e-20 73.6 1.2 2.3e-19 69.8 1.0 5.4 5 0 0 5 5 5 2 Microtubule binding Tub PF01167.18 CEP15186.1 - 1.2e-78 264.1 0.0 1.6e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Tub family PRRSV_2b PF07069.11 CEP15187.1 - 0.92 10.1 5.6 26 5.4 1.9 2.5 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b TBCC PF07986.12 CEP15188.1 - 2.4e-24 85.4 2.9 4.3e-24 84.5 2.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CEP15188.1 - 9.8e-20 71.1 4.1 2.2e-19 70.0 4.1 1.6 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DapH_N PF08503.10 CEP15188.1 - 0.018 15.2 0.3 9.3 6.6 0.1 2.9 3 0 0 3 3 3 0 Tetrahydrodipicolinate succinyltransferase N-terminal Rogdi_lz PF10259.9 CEP15188.1 - 0.046 13.2 1.3 0.097 12.1 0.8 1.6 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein GPI-anchored PF10342.9 CEP15189.1 - 2.4e-08 34.6 0.7 3.6e-08 34.1 0.7 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med4 PF10018.9 CEP15190.1 - 2.8e-25 89.2 8.3 2.8e-25 89.2 8.3 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1640 PF07798.11 CEP15191.1 - 3.7e-51 173.6 11.6 4.5e-51 173.4 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 CEP15191.1 - 0.00026 21.1 12.4 0.00026 21.1 12.4 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 CEP15191.1 - 0.028 14.0 4.5 0.034 13.7 4.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 CEP15191.1 - 0.033 13.7 15.6 0.045 13.2 15.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 CEP15191.1 - 0.041 13.7 19.3 0.19 11.6 18.3 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2163 PF09931.9 CEP15191.1 - 0.048 13.9 0.5 0.083 13.1 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) FlaC_arch PF05377.11 CEP15191.1 - 0.056 13.8 12.6 0.45 10.9 3.8 3.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF2362 PF10154.9 CEP15191.1 - 0.06 12.3 7.0 0.077 11.9 7.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF724 PF05266.14 CEP15191.1 - 0.098 12.5 17.1 0.028 14.2 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 CEP15191.1 - 0.099 11.5 13.3 0.16 10.9 13.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CEP15191.1 - 0.11 10.4 5.7 0.14 10.1 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CEP15191.1 - 0.29 11.7 15.2 1.6 9.3 8.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 CEP15191.1 - 0.31 11.3 11.7 0.36 11.1 3.6 3.3 3 1 0 3 3 2 0 Homeobox associated leucine zipper DUF4558 PF15104.6 CEP15191.1 - 0.32 11.1 11.4 2 8.5 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) DivIC PF04977.15 CEP15191.1 - 0.38 10.6 19.3 0.03 14.1 7.1 3.1 2 1 1 3 3 3 0 Septum formation initiator VRP3 PF03536.15 CEP15191.1 - 0.5 9.8 4.6 5.5 6.4 0.4 2.4 1 1 1 2 2 2 0 Salmonella virulence-associated 28kDa protein DUF2130 PF09903.9 CEP15191.1 - 0.56 9.4 15.2 0.068 12.4 7.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) XkdW PF09636.10 CEP15191.1 - 0.57 10.3 5.4 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 XkdW protein bZIP_1 PF00170.21 CEP15191.1 - 0.6 10.2 13.2 1.2 9.3 6.2 2.9 2 1 1 3 3 3 0 bZIP transcription factor LPP PF04728.13 CEP15191.1 - 0.88 10.0 6.3 7 7.1 0.9 3.0 2 1 1 3 3 2 0 Lipoprotein leucine-zipper MbeB_N PF04837.12 CEP15191.1 - 0.96 9.8 14.1 0.66 10.3 2.5 3.7 3 1 1 4 4 4 0 MbeB-like, N-term conserved region YabA PF06156.13 CEP15191.1 - 1.1 10.0 13.0 1.1 9.9 6.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 CEP15191.1 - 1.3 9.1 10.5 1.4 9.0 3.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus eIF-4B PF06273.11 CEP15191.1 - 1.4 7.8 9.6 1.8 7.6 9.6 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Occludin_ELL PF07303.13 CEP15191.1 - 1.5 9.6 10.6 1.6 9.5 4.3 2.5 1 1 0 2 2 2 0 Occludin homology domain DUF1451 PF07295.11 CEP15191.1 - 1.5 8.8 9.2 1.4 9.0 7.3 1.8 1 1 1 2 2 2 0 Zinc-ribbon containing domain RPW8 PF05659.11 CEP15191.1 - 1.6 8.4 11.4 0.57 9.9 4.7 2.2 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fungal_TACC PF12709.7 CEP15191.1 - 1.8 9.1 14.7 15 6.1 6.6 3.0 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins COG5 PF10392.9 CEP15191.1 - 2.1 8.5 10.8 5.8 7.1 10.4 2.2 1 1 0 1 1 1 0 Golgi transport complex subunit 5 bZIP_2 PF07716.15 CEP15191.1 - 2.2 8.5 16.8 2.1 8.5 1.2 3.4 2 1 1 3 3 3 0 Basic region leucine zipper Bap31_Bap29_C PF18035.1 CEP15191.1 - 2.3 8.3 19.0 5.6 7.1 2.2 3.6 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mt_ATP-synt_D PF05873.12 CEP15191.1 - 2.8 7.8 11.0 4.2 7.2 5.7 2.4 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Bcr-Abl_Oligo PF09036.10 CEP15191.1 - 3.2 7.8 7.3 1.6 8.8 2.6 2.4 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Ax_dynein_light PF10211.9 CEP15191.1 - 5.9 6.8 19.8 6.4 6.7 10.2 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1843 PF08898.10 CEP15191.1 - 6.1 7.4 8.4 3.4 8.2 2.8 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) HIP1_clath_bdg PF16515.5 CEP15191.1 - 6.5 7.4 18.1 17 6.1 0.7 2.6 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tho2 PF11262.8 CEP15191.1 - 7 5.7 13.1 44 3.1 13.1 2.0 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Vps51 PF08700.11 CEP15191.1 - 7.4 6.7 13.1 9.2 6.4 3.1 3.8 2 1 1 3 3 3 0 Vps51/Vps67 MCU PF04678.13 CEP15191.1 - 8 6.5 12.3 14 5.7 6.2 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter ECH_1 PF00378.20 CEP15192.1 - 1.1e-81 273.9 0.9 1.3e-81 273.6 0.9 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP15192.1 - 3.6e-33 115.5 1.1 4.2e-31 108.7 0.6 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CEP15192.1 - 0.015 15.3 0.2 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 CorA PF01544.18 CEP15193.1 - 0.061 12.6 1.3 0.079 12.3 1.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_L31e PF01198.19 CEP15194.1 - 0.025 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31e UPF0175 PF03683.13 CEP15194.1 - 0.084 12.6 0.5 6.1 6.6 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) NOA36 PF06524.12 CEP15195.1 - 1.3 8.3 2.9 1.8 7.8 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein NBP1 PF08537.10 CEP15196.1 - 0.023 14.1 1.9 0.027 13.9 1.9 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF5349 PF17298.2 CEP15196.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) RT_RNaseH PF17917.1 CEP15198.1 - 1.8e-36 124.6 0.0 2.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP15198.1 - 4.9e-35 119.6 0.0 8.9e-35 118.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5541 PF17695.1 CEP15198.1 - 0.047 14.1 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5541) Voltage_CLC PF00654.20 CEP15199.1 - 1.1e-81 274.9 26.0 1.1e-81 274.9 26.0 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CEP15199.1 - 2.8e-05 24.5 0.0 0.00053 20.4 0.0 2.8 3 0 0 3 3 3 1 CBS domain Haspin_kinase PF12330.8 CEP15199.1 - 0.081 11.9 0.5 0.12 11.3 0.5 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PDZ_5 PF17817.1 CEP15200.1 - 7.8e-05 22.9 2.2 9.4e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 PDZ domain CotH PF08757.11 CEP15201.1 - 1.5e-48 166.0 0.7 2.2e-48 165.4 0.7 1.2 1 0 0 1 1 1 1 CotH kinase protein zf-ANAPC11 PF12861.7 CEP15202.1 - 3.1e-35 120.1 11.7 3.5e-35 119.9 11.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEP15202.1 - 3.6e-21 75.2 12.9 4.7e-21 74.8 12.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEP15202.1 - 2.1e-05 24.8 18.0 0.00058 20.1 18.0 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CEP15202.1 - 0.0044 17.0 10.9 0.037 14.0 11.2 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP15202.1 - 0.005 16.8 11.5 0.012 15.6 11.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CEP15202.1 - 0.09 12.5 13.0 1 9.2 13.0 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 CEP15202.1 - 0.11 12.4 15.5 0.76 9.7 15.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEP15202.1 - 1 9.0 19.9 1.3 8.7 15.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CEP15202.1 - 6.3 7.1 17.9 60 3.9 18.0 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 CEP15202.1 - 7.4 6.5 19.8 1.7e+02 2.2 19.8 2.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S8e PF01201.22 CEP15203.1 - 6.8e-53 178.5 0.8 6.8e-53 178.5 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S8e SPX PF03105.19 CEP15203.1 - 1.1e-33 117.7 14.3 3.4e-27 96.4 4.4 3.3 2 1 1 3 3 3 2 SPX domain Ribosomal_L5_C PF00673.21 CEP15203.1 - 3.9e-21 75.0 0.0 1.2e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEP15203.1 - 1.1e-19 70.5 0.0 2.6e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 DUF2627 PF11118.8 CEP15204.1 - 0.0035 17.9 0.0 0.0059 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) PTP_tm PF18861.1 CEP15204.1 - 0.0041 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 CEP15204.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 CEP15204.1 - 0.013 15.4 0.4 0.025 14.5 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain ACP PF06857.11 CEP15204.1 - 0.038 14.2 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Gram_pos_anchor PF00746.21 CEP15204.1 - 0.039 13.9 1.8 0.079 12.9 1.8 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Orf78 PF06024.12 CEP15204.1 - 0.053 13.8 3.7 1.2 9.5 0.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) DUF1206 PF06724.11 CEP15204.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) ABC2_membrane_2 PF12679.7 CEP15204.1 - 0.098 11.9 0.3 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Rsa3 PF14615.6 CEP15205.1 - 5.8e-17 61.0 0.0 1.8e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Ribosome-assembly protein 3 DUF2039 PF10217.9 CEP15206.1 - 5e-27 94.1 19.3 8.3e-27 93.4 19.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 CEP15206.1 - 0.29 11.1 12.3 0.63 10.1 12.3 1.6 1 0 0 1 1 1 0 zinc-ribbons Cript PF10235.9 CEP15206.1 - 7.4 7.2 23.6 37 5.0 23.1 2.3 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-RING_5 PF14634.6 CEP15206.1 - 8.1 6.5 13.9 0.24 11.4 2.3 2.4 2 0 0 2 2 2 0 zinc-RING finger domain OST3_OST6 PF04756.13 CEP15207.1 - 5.5e-103 344.3 0.2 6.8e-103 344.0 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CEP15207.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin MerC PF03203.14 CEP15207.1 - 2.3 8.7 6.2 1.8 9.0 0.2 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.6 CEP15207.1 - 4 7.1 9.1 1.9 8.1 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PHD PF00628.29 CEP15208.1 - 0.00032 20.5 8.3 0.00032 20.5 8.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CEP15208.1 - 0.011 15.4 3.2 0.011 15.4 3.2 1.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 CEP15208.1 - 0.016 15.1 4.4 0.016 15.1 4.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Polysacc_deac_1 PF01522.21 CEP15209.1 - 1.5e-19 70.1 0.0 2.9e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3800 PF12686.7 CEP15210.1 - 0.058 14.0 0.1 1.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) Trypan_glycop_C PF10659.9 CEP15211.1 - 0.056 13.8 0.2 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain SQS_PSY PF00494.19 CEP15212.1 - 1.3e-51 175.6 0.0 1.5e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SoDot-IcmSS PF16848.5 CEP15212.1 - 0.085 12.8 0.7 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative zf-C2H2_12 PF18658.1 CEP15213.1 - 0.072 12.7 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type PhyH PF05721.13 CEP15214.1 - 6.9e-10 39.5 0.1 1.4e-09 38.5 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_C14 PF00656.22 CEP15215.1 - 3.6e-58 197.4 0.2 4.6e-58 197.1 0.2 1.1 1 0 0 1 1 1 1 Caspase domain RNA_pol_L_2 PF13656.6 CEP15216.1 - 9.1e-32 108.7 0.1 1.3e-31 108.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEP15216.1 - 8.3e-11 41.2 0.0 1.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RPN2_C PF18004.1 CEP15216.1 - 0.71 9.8 5.9 1.2 9.0 5.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 CEP15216.1 - 4.4 5.3 9.8 5 5.1 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi TP_methylase PF00590.20 CEP15217.1 - 4.5e-24 85.6 0.1 7.9e-24 84.8 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Apolipoprotein PF01442.18 CEP15218.1 - 0.00013 22.0 4.1 0.00015 21.7 4.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 CEP15218.1 - 0.011 15.7 0.2 0.015 15.2 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein O Exonuc_VII_L PF02601.15 CEP15218.1 - 0.012 15.2 0.3 0.012 15.2 0.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 CEP15218.1 - 0.015 14.2 0.4 0.016 14.1 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 CEP15218.1 - 0.028 14.8 7.9 0.034 14.5 7.9 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 CEP15218.1 - 0.034 13.4 0.2 0.038 13.3 0.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein GrpE PF01025.19 CEP15218.1 - 0.04 13.6 6.4 0.12 12.1 6.4 1.7 1 1 0 1 1 1 0 GrpE GCN5L1 PF06320.13 CEP15218.1 - 0.051 13.7 3.8 0.06 13.5 3.8 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Fib_alpha PF08702.10 CEP15218.1 - 0.12 12.6 1.3 0.14 12.3 1.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 CEP15218.1 - 0.12 12.7 5.0 0.077 13.3 3.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CEP15218.1 - 0.14 11.5 5.7 0.17 11.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CEP15218.1 - 0.17 12.0 4.9 0.2 11.7 4.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.13 CEP15218.1 - 0.29 11.7 10.6 0.13 12.9 5.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CLZ PF16526.5 CEP15218.1 - 0.33 11.4 4.4 0.31 11.4 1.7 1.9 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4337 PF14235.6 CEP15218.1 - 0.33 11.1 2.5 0.41 10.7 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1664 PF07889.12 CEP15218.1 - 0.38 10.8 1.4 0.56 10.3 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 CEP15218.1 - 0.45 10.6 6.4 0.79 9.9 6.4 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Pinin_SDK_memA PF04696.13 CEP15218.1 - 0.46 10.5 4.9 0.57 10.3 4.9 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region KfrA_N PF11740.8 CEP15218.1 - 0.56 10.9 8.7 0.74 10.5 8.7 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DivIVA PF05103.13 CEP15218.1 - 0.75 9.9 7.6 1.1 9.4 7.6 1.3 1 0 0 1 1 1 0 DivIVA protein HisKA_3 PF07730.13 CEP15218.1 - 1.2 9.7 5.3 3 8.4 1.7 2.1 1 1 1 2 2 2 0 Histidine kinase DUF3987 PF13148.6 CEP15218.1 - 1.5 7.8 5.8 1.7 7.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP-synt_B PF00430.18 CEP15218.1 - 1.7 8.7 11.9 2.5 8.2 11.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MtrG PF04210.13 CEP15218.1 - 5.1 7.0 6.6 25 4.8 0.4 3.2 2 1 2 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Nup96 PF12110.8 CEP15219.1 - 2.4e-13 49.8 10.4 3.8e-12 45.9 0.4 3.1 3 1 0 4 4 4 2 Nuclear protein 96 MoaE PF02391.17 CEP15220.1 - 1.6e-37 128.2 0.1 1.9e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Pkinase PF00069.25 CEP15221.1 - 1.6e-69 234.2 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15221.1 - 3.7e-32 111.6 0.0 5.3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 CEP15221.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase_fungal PF17667.1 CEP15221.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_L10 PF00466.20 CEP15222.1 - 1.5e-21 76.4 0.2 2.2e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CEP15222.1 - 7.6e-21 73.9 0.0 1.1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Myb_DNA-binding PF00249.31 CEP15223.1 - 2.9e-10 40.1 2.8 0.00015 21.9 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP15223.1 - 4.3e-10 39.7 2.3 5.4e-07 29.8 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CEP15223.1 - 0.031 14.4 0.3 5.7 7.2 0.1 2.7 2 1 0 2 2 2 0 Rap1 Myb domain Tctex-1 PF03645.13 CEP15223.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Tctex-1 family Rap1_C PF11626.8 CEP15223.1 - 0.058 13.5 0.1 2.4 8.3 0.1 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SUZ PF12752.7 CEP15223.1 - 0.37 11.6 8.4 0.43 11.4 0.0 3.0 3 1 0 3 3 3 0 SUZ domain Chi-conotoxin PF16981.5 CEP15223.1 - 0.41 10.9 1.8 0.54 10.5 0.2 2.1 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily NUDE_C PF04880.13 CEP15223.1 - 4.1 7.9 9.0 7.8 6.9 9.0 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pkinase_Tyr PF07714.17 CEP15224.1 - 1.1e-29 103.5 0.0 2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.26 CEP15224.1 - 2e-29 102.3 0.1 4.4e-29 101.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 CEP15224.1 - 3e-27 95.6 0.0 5.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Response_reg PF00072.24 CEP15224.1 - 2.1e-21 76.2 0.0 8.6e-21 74.2 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain Peripla_BP_4 PF13407.6 CEP15224.1 - 8.6e-18 64.8 2.7 2.3e-09 37.2 1.1 3.4 2 1 1 3 3 3 2 Periplasmic binding protein domain HisKA PF00512.25 CEP15224.1 - 1.6e-17 63.3 0.0 6.2e-17 61.4 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ephrin_rec_like PF07699.13 CEP15224.1 - 1.1e-05 25.1 9.7 0.00015 21.5 2.7 2.7 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 CEP15224.1 - 0.014 15.3 9.4 0.012 15.6 2.4 2.6 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF5617 PF18493.1 CEP15224.1 - 0.046 13.8 0.1 0.25 11.5 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) UPF0261 PF06792.11 CEP15224.1 - 0.071 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Fmp27_WPPW PF10359.9 CEP15224.1 - 0.095 11.5 0.5 0.16 10.8 0.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TNFR_c6 PF00020.18 CEP15224.1 - 6.7 7.2 10.2 3.8 8.0 2.1 3.0 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region Retrotrans_gag PF03732.17 CEP15225.1 - 0.0057 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein ILVD_EDD PF00920.21 CEP15227.1 - 0.036 12.7 0.1 0.05 12.2 0.1 1.1 1 0 0 1 1 1 0 Dehydratase family DUF4064 PF13273.6 CEP15227.1 - 2.2 8.6 9.3 0.31 11.3 3.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) TIMELESS PF04821.14 CEP15228.1 - 2e-57 194.6 1.9 3.7e-57 193.7 0.5 2.2 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 CEP15228.1 - 3.1e-08 33.3 0.6 3.1e-08 33.3 0.6 2.2 2 0 0 2 2 2 2 Timeless protein C terminal region OAD_gamma PF04277.13 CEP15228.1 - 0.13 12.8 0.3 0.44 11.2 0.3 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CBS PF00571.28 CEP15229.1 - 2.1e-30 105.0 7.4 1.1e-08 35.4 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 CEP15229.1 - 3.8e-06 26.8 0.2 8.2e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 PB1 domain RNA_pol_Rpc82 PF05645.13 CEP15229.1 - 3.9 7.2 6.8 4 7.1 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 MFS_1 PF07690.16 CEP15230.1 - 1.6e-37 129.3 36.2 1.6e-37 129.3 36.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-CCCH_2 PF14608.6 CEP15231.1 - 5.8e-17 61.5 55.0 5.3e-05 23.5 9.5 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CEP15231.1 - 0.0085 16.3 0.7 0.0085 16.3 0.7 2.7 2 1 0 2 2 2 1 Zinc-finger containing family Ndc1_Nup PF09531.10 CEP15231.1 - 4.2 5.9 5.2 5.5 5.5 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glycogen_syn PF05693.13 CEP15232.1 - 0 1084.1 0.0 0 1083.1 0.0 1.4 1 1 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CEP15232.1 - 8.7e-06 25.4 0.0 0.00033 20.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP15232.1 - 2.8e-05 24.5 0.0 0.0057 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CEP15232.1 - 4.6e-05 23.2 0.5 0.00018 21.3 0.2 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 CEP15232.1 - 0.00036 20.6 0.4 0.00071 19.6 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 cobW PF02492.19 CEP15233.1 - 1.7e-41 141.8 0.2 2.5e-41 141.2 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEP15233.1 - 3.2e-05 23.8 0.0 5.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 CEP15233.1 - 0.0019 18.1 0.1 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF4315 PF14193.6 CEP15233.1 - 0.0024 17.8 0.6 0.011 15.7 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4315) tRNA_anti-codon PF01336.25 CEP15233.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RsgA_GTPase PF03193.16 CEP15233.1 - 0.008 16.1 0.2 2 8.3 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase Pox_A32 PF04665.12 CEP15233.1 - 0.044 13.2 0.1 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein Viral_helicase1 PF01443.18 CEP15233.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CEP15233.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rhomboid PF01694.22 CEP15234.1 - 2.1e-26 92.7 8.5 3.4e-26 92.1 8.5 1.2 1 0 0 1 1 1 1 Rhomboid family Pex14_N PF04695.13 CEP15234.1 - 2.6 8.7 6.1 5 7.8 6.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_transf_20 PF00982.21 CEP15235.1 - 8.7e-149 496.2 0.1 1.2e-148 495.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP15235.1 - 4.7e-74 248.4 0.0 6.3e-73 244.8 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEP15235.1 - 1.1e-05 25.4 0.0 0.004 16.9 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CEP15235.1 - 0.0075 15.8 0.0 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase PA PF02225.22 CEP15236.1 - 0.0002 21.3 0.0 0.00049 20.1 0.0 1.7 1 1 1 2 2 2 1 PA domain cobW PF02492.19 CEP15237.1 - 3e-49 167.0 0.5 4.4e-49 166.5 0.5 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CEP15237.1 - 8.6e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CEP15237.1 - 0.00032 20.6 1.0 0.91 9.4 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEP15237.1 - 0.0069 16.7 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CEP15237.1 - 0.0072 15.4 1.5 0.016 14.3 0.1 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 CEP15237.1 - 0.0073 16.2 0.1 0.0073 16.2 0.1 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CEP15237.1 - 0.026 14.6 0.2 0.097 12.8 0.1 2.1 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CEP15237.1 - 0.027 14.5 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CEP15237.1 - 0.035 13.9 0.5 0.078 12.7 0.5 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CEP15237.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CEP15237.1 - 0.052 14.1 0.7 0.18 12.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CEP15237.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CEP15237.1 - 0.073 13.6 7.0 3.9 7.9 1.2 3.0 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 CEP15237.1 - 0.073 13.6 0.6 0.24 11.9 0.1 2.1 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 CEP15237.1 - 0.081 12.5 6.2 2.3 7.7 2.7 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CEP15237.1 - 0.081 12.7 0.1 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Proteasom_Rpn13 PF04683.13 CEP15238.1 - 5.2e-18 65.4 0.4 5.3e-15 55.7 0.1 2.9 2 1 1 3 3 3 2 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CEP15238.1 - 3.9e-14 52.8 1.2 6.9e-13 48.8 1.3 2.2 1 1 1 2 2 2 1 UCH-binding domain RINGv PF12906.7 CEP15239.1 - 4.8e-07 29.8 10.1 8e-07 29.1 10.1 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 CEP15239.1 - 0.00044 20.4 6.4 0.00078 19.6 6.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 CEP15239.1 - 0.00051 19.8 6.1 0.00084 19.1 6.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CEP15239.1 - 0.0024 18.2 7.0 0.0039 17.5 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain AAA_assoc PF14363.6 CEP15239.1 - 0.048 14.0 0.3 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA Prok-RING_1 PF14446.6 CEP15239.1 - 0.086 12.8 0.3 0.086 12.8 0.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_5 PF13719.6 CEP15239.1 - 0.18 11.6 1.3 2 8.2 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PHD PF00628.29 CEP15239.1 - 0.87 9.5 8.0 1.7 8.6 7.2 1.8 1 1 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.25 CEP15239.1 - 2.5 8.1 6.0 4.1 7.3 6.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S1 PF00575.23 CEP15240.1 - 2.1e-14 53.6 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CEP15240.1 - 5.5e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S-AdoMet_synt_C PF02773.16 CEP15241.1 - 1.2e-68 229.3 0.4 2.9e-68 228.2 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CEP15241.1 - 1.3e-46 157.7 0.0 2.7e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CEP15241.1 - 1.2e-45 154.2 0.7 2.2e-45 153.4 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CEP15241.1 - 0.028 13.2 0.8 0.13 11.0 0.2 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SNF2_N PF00176.23 CEP15242.1 - 8.6e-65 218.7 0.5 1.8e-64 217.7 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 CEP15242.1 - 1.7e-50 170.8 19.5 1.7e-50 170.8 19.5 3.5 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 CEP15242.1 - 4.7e-17 62.3 0.3 1.4e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP15242.1 - 3e-06 27.3 2.0 4.3e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CEP15242.1 - 0.0039 16.4 0.0 0.0039 16.4 0.0 3.0 4 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 MyTH4 PF00784.17 CEP15242.1 - 0.85 10.1 8.8 5 7.7 0.3 3.9 3 1 1 4 4 4 0 MyTH4 domain Ras PF00071.22 CEP15243.1 - 1.3e-37 128.9 0.0 1.6e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15243.1 - 9.8e-14 51.6 0.0 1.7e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15243.1 - 0.00041 19.9 0.0 0.00055 19.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP15243.1 - 0.0034 16.9 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ICL PF00463.21 CEP15244.1 - 3.1e-263 874.0 0.7 3.5e-263 873.9 0.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CEP15244.1 - 1.5e-09 37.7 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1741 PF08427.10 CEP15245.1 - 7.4e-55 186.1 3.4 7.4e-55 186.1 3.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) LRR_4 PF12799.7 CEP15246.1 - 1.1e-05 25.7 10.6 0.24 11.9 0.2 5.6 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CEP15246.1 - 0.00026 20.8 0.7 0.0014 18.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP15246.1 - 0.00092 19.0 0.1 0.0042 16.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 CEP15246.1 - 0.0051 17.2 7.2 7 7.6 0.1 5.3 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 CEP15246.1 - 0.028 14.2 1.7 5.1 6.9 0.1 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 CEP15246.1 - 0.1 12.7 11.1 0.73 10.0 0.5 5.2 6 0 0 6 6 6 0 Leucine Rich repeat Adap_comp_sub PF00928.21 CEP15247.1 - 3.9e-94 314.9 0.2 5.9e-94 314.3 0.2 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEP15247.1 - 1.4e-10 41.3 0.4 2.4e-10 40.5 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 CEP15247.1 - 0.034 13.2 0.1 0.048 12.7 0.1 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Metallophos PF00149.28 CEP15248.1 - 2.2e-14 54.4 0.3 4.1e-14 53.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP15248.1 - 2.9e-05 24.3 1.5 8.9e-05 22.7 1.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pneumo_att_G PF05539.11 CEP15248.1 - 0.0028 17.3 1.8 0.0046 16.6 1.8 1.2 1 0 0 1 1 1 1 Pneumovirinae attachment membrane glycoprotein G dUTPase PF00692.19 CEP15249.1 - 2.9e-42 143.4 0.0 3.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase Lactamase_B_4 PF13691.6 CEP15250.1 - 1e-18 66.8 0.0 2e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CEP15250.1 - 7.7e-14 51.7 0.0 6.1e-10 38.9 0.0 2.7 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEP15250.1 - 9.6e-07 29.0 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Reticulon PF02453.17 CEP15252.1 - 3.9e-22 78.9 3.8 5.3e-22 78.5 3.8 1.2 1 0 0 1 1 1 1 Reticulon GAD-like PF08887.11 CEP15253.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain Peptidase_M22 PF00814.25 CEP15254.1 - 1.7e-87 293.6 0.0 2e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CEP15254.1 - 0.0042 16.8 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Cpn10 PF00166.21 CEP15255.1 - 2e-32 111.1 0.1 2.3e-32 110.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit CxC2 PF18803.1 CEP15256.1 - 5.5e-06 26.5 0.1 1.6e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 CEP15256.1 - 0.00075 19.2 0.6 0.029 14.0 0.1 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 CEP15257.1 - 1.3e-06 28.2 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CHORD PF04968.12 CEP15258.1 - 2.2e-51 172.4 25.0 7.3e-27 93.9 6.7 2.6 2 0 0 2 2 2 2 CHORD Brix PF04427.18 CEP15258.1 - 4.5e-45 154.1 0.4 1.5e-44 152.4 0.1 1.9 2 0 0 2 2 2 1 Brix domain CS PF04969.16 CEP15258.1 - 3.3e-13 50.4 1.4 7.3e-13 49.3 1.4 1.6 1 0 0 1 1 1 1 CS domain DUF4820 PF16091.5 CEP15258.1 - 1.1 8.6 7.8 2.2 7.6 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) G0-G1_switch_2 PF15103.6 CEP15258.1 - 1.5 9.3 5.4 1.2 9.6 2.7 2.3 1 1 1 2 2 2 0 G0/G1 switch protein 2 Spem1 PF15670.5 CEP15258.1 - 9.4 5.7 8.2 72 2.8 6.4 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 BTK PF00779.19 CEP15258.1 - 9.7 6.1 12.6 8.1 6.4 0.2 2.9 3 0 0 3 3 3 0 BTK motif DUF2019 PF09450.10 CEP15260.1 - 0.041 13.8 1.4 3.6 7.6 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF2019) Sel1 PF08238.12 CEP15261.1 - 3e-32 110.3 19.2 1e-06 29.2 0.2 7.4 7 0 0 7 7 7 6 Sel1 repeat Serinc PF03348.15 CEP15261.1 - 1 8.2 3.4 1.5 7.6 3.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CEP15261.1 - 3 6.5 5.5 4.3 6.0 5.5 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CEP15262.1 - 1.1e-67 228.2 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15262.1 - 2.6e-30 105.6 0.0 3.9e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP15262.1 - 1.6e-05 24.1 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP15262.1 - 6e-05 22.5 0.1 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP15262.1 - 0.00039 20.4 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEP15262.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CEP15262.1 - 0.036 13.4 0.0 0.29 10.4 0.0 2.0 1 1 0 2 2 2 0 Kinase-like RIO1 PF01163.22 CEP15262.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family UPF0113_N PF17833.1 CEP15263.1 - 8.9e-32 109.5 0.1 1.5e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CEP15263.1 - 1.5e-24 86.0 0.0 2.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain Senescence PF06911.12 CEP15264.1 - 0.0066 16.8 12.9 0.13 12.6 1.9 3.6 1 1 2 3 3 3 3 Senescence-associated protein Collagen_mid PF15984.5 CEP15264.1 - 8.9 6.0 57.0 0.13 12.0 7.0 3.7 1 1 2 4 4 4 0 Bacterial collagen, middle region D-ser_dehydrat PF14031.6 CEP15265.1 - 2.7e-21 76.0 0.0 6.4e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CEP15265.1 - 5.5e-19 68.7 0.0 7.4e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA-synt_1 PF00133.22 CEP15266.1 - 5.5e-179 596.3 0.0 1.4e-177 591.7 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEP15266.1 - 1.5e-23 83.5 0.1 1.5e-17 64.0 0.0 2.5 2 0 0 2 2 2 2 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEP15266.1 - 9e-18 64.2 4.6 3.1e-07 29.5 0.0 5.1 4 2 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEP15266.1 - 1e-08 34.9 0.0 1.5e-07 31.1 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CEP15266.1 - 9.1e-07 28.5 0.0 0.011 15.1 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 CEP15266.1 - 0.0069 16.7 1.4 0.019 15.3 1.4 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 CEP15266.1 - 0.031 13.6 0.1 0.43 9.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) SR-25 PF10500.9 CEP15266.1 - 0.12 11.9 3.9 0.41 10.2 3.2 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ABC_membrane PF00664.23 CEP15267.1 - 2.8e-116 388.0 19.7 2.3e-59 201.3 10.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP15267.1 - 2.9e-70 235.1 0.1 7.6e-35 120.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP15267.1 - 3.9e-13 49.3 6.6 1.9e-05 24.2 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEP15267.1 - 3.7e-09 35.9 0.5 5.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CEP15267.1 - 2.1e-08 34.5 0.5 0.0048 17.2 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CEP15267.1 - 1.3e-07 32.2 1.4 0.029 14.8 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CEP15267.1 - 6.2e-07 29.5 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CEP15267.1 - 7.6e-06 25.8 1.4 0.29 10.8 0.3 3.8 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CEP15267.1 - 1.2e-05 24.9 1.2 0.099 12.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CEP15267.1 - 4.9e-05 22.7 0.1 0.03 13.6 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.15 CEP15267.1 - 5.4e-05 23.2 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 CEP15267.1 - 0.00011 22.4 0.0 0.87 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 CEP15267.1 - 0.00012 21.4 0.0 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 CEP15267.1 - 0.00019 21.9 5.3 1.6 9.2 1.2 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CEP15267.1 - 0.00019 21.0 0.0 0.83 9.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 CEP15267.1 - 0.0009 19.4 5.4 0.87 9.9 0.3 4.3 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 CEP15267.1 - 0.0016 18.8 0.0 5.2 7.5 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 CEP15267.1 - 0.0024 18.4 0.0 3.1 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CEP15267.1 - 0.0029 17.9 0.1 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CEP15267.1 - 0.0035 17.0 0.2 1.1 8.8 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 CEP15267.1 - 0.0045 17.0 0.1 8.5 6.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEP15267.1 - 0.0062 16.3 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CEP15267.1 - 0.0082 15.9 0.2 0.41 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CEP15267.1 - 0.024 13.8 0.0 0.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CEP15267.1 - 0.026 14.2 1.9 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase AAA_21 PF13304.6 CEP15267.1 - 0.037 13.8 0.1 36 4.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 CEP15267.1 - 0.07 12.9 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 CEP15267.1 - 0.099 12.5 0.0 18 5.2 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 CEP15267.1 - 0.1 11.8 0.8 16 4.6 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain DUF2207 PF09972.9 CEP15267.1 - 0.12 11.2 0.0 0.12 11.2 0.0 4.2 4 1 0 4 4 3 0 Predicted membrane protein (DUF2207) MMR_HSR1 PF01926.23 CEP15267.1 - 0.13 12.3 0.6 27 4.9 0.0 3.2 4 0 0 4 4 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 CEP15267.1 - 0.26 10.9 1.9 14 5.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CEP15267.1 - 0.42 10.3 2.3 29 4.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein Proteasome PF00227.26 CEP15269.1 - 6.8e-28 97.4 0.0 8.3e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldo_ket_red PF00248.21 CEP15270.1 - 1.3e-39 136.2 0.0 1.5e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cyclase_polyket PF04673.12 CEP15270.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthesis cyclase Acyl-CoA_dh_1 PF00441.24 CEP15271.1 - 1.7e-35 122.4 1.2 2.7e-35 121.8 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEP15271.1 - 1.1e-21 76.8 0.1 2.2e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 CEP15271.1 - 3.1e-21 75.3 0.0 6.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CEP15271.1 - 7.3e-16 58.8 0.0 4.7e-15 56.2 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DSPc PF00782.20 CEP15272.1 - 2.3e-32 111.6 0.2 4e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP15272.1 - 0.0086 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CEP15272.1 - 0.043 13.5 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 CEP15272.1 - 0.091 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Yippee-Mis18 PF03226.14 CEP15272.1 - 1.8 8.8 4.7 0.92 9.8 0.1 2.6 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glycos_transf_1 PF00534.20 CEP15273.1 - 1.5e-14 53.9 0.0 2.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP15273.1 - 3.1e-10 40.6 0.0 7.1e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEP15273.1 - 6.5e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CEP15273.1 - 6.1e-06 26.8 0.0 1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CEP15273.1 - 8.9e-05 22.6 0.1 0.00015 21.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF4771 PF15995.5 CEP15273.1 - 0.084 13.1 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) Methyltransf_11 PF08241.12 CEP15274.1 - 1.3e-16 61.0 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP15274.1 - 3.3e-16 59.8 0.0 6.8e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP15274.1 - 3.5e-13 49.7 0.0 5.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP15274.1 - 5.6e-10 39.2 0.0 1.2e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP15274.1 - 2e-06 27.3 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP15274.1 - 9.5e-06 26.3 0.0 2.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP15274.1 - 3e-05 23.6 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 CEP15274.1 - 0.00079 19.3 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 CEP15274.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 CEP15274.1 - 0.0024 17.4 0.0 0.0077 15.7 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 CEP15274.1 - 0.0046 16.3 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 CEP15274.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEP15274.1 - 0.17 11.4 0.0 0.57 9.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain G_path_suppress PF15991.5 CEP15275.1 - 1e-05 25.8 13.6 1e-05 25.8 13.6 1.8 1 1 1 2 2 2 1 G-protein pathway suppressor PIEZO PF15917.5 CEP15275.1 - 0.011 15.3 5.3 0.016 14.7 5.3 1.3 1 0 0 1 1 1 0 Piezo Complex1_LYR PF05347.15 CEP15276.1 - 7e-19 67.6 0.2 9.9e-19 67.2 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEP15276.1 - 0.00016 22.4 0.0 0.00018 22.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CEP15276.1 - 0.0041 17.7 0.1 0.0049 17.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like CTNNBL PF08216.11 CEP15277.1 - 2.1e-39 133.9 1.6 2.1e-39 133.9 1.6 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear LemA PF04011.12 CEP15277.1 - 0.061 13.2 6.1 0.078 12.8 0.2 2.8 3 0 0 3 3 3 0 LemA family cwf21 PF08312.12 CEP15278.1 - 3.9e-16 58.9 5.5 3.9e-16 58.9 5.5 3.5 3 1 0 4 4 4 2 cwf21 domain NUDIX PF00293.28 CEP15279.1 - 4.1e-15 56.0 0.2 1e-14 54.7 0.2 1.7 1 0 0 1 1 1 1 NUDIX domain TFIIF_alpha PF05793.12 CEP15279.1 - 9.1e-07 27.8 30.2 1.3e-06 27.3 30.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hydin_ADK PF17213.3 CEP15279.1 - 0.021 15.1 6.5 0.053 13.8 6.5 1.7 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAP2 PF01569.21 CEP15280.1 - 2.2e-29 102.0 0.4 2.2e-29 102.0 0.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF5510 PF17629.2 CEP15280.1 - 0.048 13.6 2.2 0.093 12.7 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Sacchrp_dh_NADP PF03435.18 CEP15281.1 - 6.2e-16 58.8 0.0 9.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CEP15281.1 - 0.0046 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CEP15281.1 - 0.028 14.4 0.2 0.069 13.1 0.0 1.6 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 CEP15281.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Peptidase_M1 PF01433.20 CEP15282.1 - 3e-46 157.7 0.0 4.3e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CEP15282.1 - 4.3e-38 129.9 0.1 7.8e-38 129.0 0.1 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CEP15282.1 - 2.2e-23 83.4 0.1 3.3e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Elf1 PF05129.13 CEP15284.1 - 0.071 13.2 0.3 0.24 11.5 0.6 1.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like ORF6C PF10552.9 CEP15285.1 - 0.0054 16.8 0.9 0.007 16.4 0.8 1.5 1 1 0 1 1 1 1 ORF6C domain Prefoldin_2 PF01920.20 CEP15285.1 - 0.011 15.6 0.5 0.015 15.3 0.5 1.3 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 CEP15285.1 - 0.012 16.1 0.3 0.021 15.3 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Dynamitin PF04912.14 CEP15285.1 - 0.013 14.9 0.6 0.02 14.2 0.6 1.4 1 1 0 1 1 1 0 Dynamitin dCache_1 PF02743.18 CEP15285.1 - 0.015 15.1 0.3 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 Cache domain RPW8 PF05659.11 CEP15285.1 - 0.021 14.5 0.2 0.044 13.5 0.1 1.5 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Vps5 PF09325.10 CEP15285.1 - 0.031 13.8 0.6 0.038 13.5 0.5 1.3 1 1 0 1 1 1 0 Vps5 C terminal like TRPM_tetra PF16519.5 CEP15285.1 - 0.064 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM CDT1_C PF16679.5 CEP15285.1 - 0.081 13.4 0.1 0.13 12.7 0.1 1.5 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain V_ATPase_I PF01496.19 CEP15285.1 - 0.1 10.5 2.7 0.1 10.5 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CEP15285.1 - 0.1 12.6 0.6 0.15 12.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) gag-asp_proteas PF13975.6 CEP15286.1 - 5.5e-08 33.3 0.1 1.4e-06 28.8 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4939 PF16297.5 CEP15286.1 - 4.9e-06 26.4 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 CEP15286.1 - 0.0007 20.2 0.1 0.0028 18.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF4686 PF15742.5 CEP15286.1 - 0.00078 18.7 4.3 0.0012 18.0 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Allexi_40kDa PF05549.11 CEP15286.1 - 0.013 15.1 3.3 0.037 13.5 3.3 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein RVP_2 PF08284.11 CEP15286.1 - 0.12 12.1 0.0 0.44 10.3 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease RAC_head PF16717.5 CEP15286.1 - 0.24 12.4 1.3 2.9 8.9 1.8 2.3 2 0 0 2 2 2 0 Ribosome-associated complex head domain HMMR_N PF15905.5 CEP15286.1 - 0.38 10.2 7.6 0.77 9.2 7.6 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 CEP15286.1 - 0.48 9.0 2.1 0.86 8.1 2.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 CEP15286.1 - 1.6 8.7 8.3 0.85 9.7 5.6 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-AD PF07776.15 CEP15287.1 - 0.0085 16.3 0.4 0.022 15.0 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) zf-C2H2_3rep PF18868.1 CEP15287.1 - 0.1 13.3 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CEP15287.1 - 0.85 10.6 4.3 1.5 9.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP15287.1 - 3.9 8.1 5.4 13 6.4 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf_C2H2_10 PF18414.1 CEP15287.1 - 4.3 6.9 5.3 2.2 7.9 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger Retrotrans_gag PF03732.17 CEP15288.1 - 0.00023 21.4 1.3 0.0007 19.8 0.3 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP15288.1 - 0.0018 18.8 0.7 0.0068 16.9 0.1 2.5 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP15288.1 - 0.0049 17.5 0.2 0.033 14.8 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease RVP PF00077.20 CEP15288.1 - 0.035 14.4 0.2 0.29 11.4 0.0 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease RVP_2 PF08284.11 CEP15288.1 - 0.04 13.7 0.3 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 CEP15289.1 - 6.4e-25 87.1 0.0 2.9e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP15289.1 - 2.2e-15 56.8 0.1 2.5e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP15289.1 - 6.3e-12 45.4 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 CEP15289.1 - 5.1e-10 39.3 0.3 5.1e-10 39.3 0.3 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP15289.1 - 3.3e-07 30.5 0.0 1.2e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP15289.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain MLVIN_C PF18697.1 CEP15289.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Glycoprot_B_PH2 PF17417.2 CEP15289.1 - 0.052 13.9 0.4 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain DDE_3 PF13358.6 CEP15290.1 - 5.5e-24 84.6 0.0 2.7e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP15290.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.19 CEP15290.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.6 CEP15290.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix Aldo_ket_red PF00248.21 CEP15291.1 - 4.5e-55 186.9 0.1 4.5e-54 183.6 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family YjcQ PF09639.10 CEP15291.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 YjcQ protein Sacchrp_dh_NADP PF03435.18 CEP15291.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.5 2 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain RPN7 PF10602.9 CEP15292.1 - 2.2e-39 134.9 0.6 2.2e-39 134.9 0.6 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CEP15292.1 - 9.1e-18 64.7 2.3 1.6e-17 63.9 1.1 2.1 2 0 0 2 2 2 1 PCI domain MIT PF04212.18 CEP15292.1 - 0.06 13.4 0.6 5.3 7.2 0.2 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CEP15292.1 - 0.16 11.7 0.8 15 5.4 0.2 2.9 3 0 0 3 3 3 0 TPR repeat RBP_receptor PF14752.6 CEP15293.1 - 1e-08 34.3 12.9 5.8e-08 31.8 12.9 2.1 1 1 0 1 1 1 1 Retinol binding protein receptor LAT PF15234.6 CEP15293.1 - 0.38 10.4 2.7 0.64 9.7 2.7 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DDE_3 PF13358.6 CEP15294.1 - 1.7e-17 63.6 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Cyt-b5 PF00173.28 CEP15294.1 - 4.4e-11 42.8 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DDE_Tnp_ISAZ013 PF07592.11 CEP15294.1 - 0.19 10.7 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Cation_efflux PF01545.21 CEP15295.1 - 2e-41 141.9 7.7 3.5e-35 121.6 3.0 2.3 2 0 0 2 2 2 2 Cation efflux family ZT_dimer PF16916.5 CEP15295.1 - 5e-09 36.2 0.1 9.6e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Polbeta PF18765.1 CEP15295.1 - 0.18 11.9 0.2 24 5.1 0.0 2.9 2 1 1 3 3 3 0 Polymerase beta, Nucleotidyltransferase Steroid_dh PF02544.16 CEP15296.1 - 2.6e-39 134.6 1.9 4.3e-39 133.9 1.9 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CEP15296.1 - 7.3e-07 28.9 0.4 1.4e-06 28.0 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CEP15296.1 - 0.001 19.5 0.9 0.0041 17.5 0.9 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 CEP15296.1 - 0.057 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Myb_DNA-binding PF00249.31 CEP15297.1 - 1.4e-34 118.0 6.3 7.3e-08 32.5 0.0 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP15297.1 - 3.1e-28 97.8 1.6 1.4e-08 34.8 0.0 4.2 3 1 1 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEP15297.1 - 1.7e-08 34.3 1.0 0.16 11.9 0.0 4.9 2 2 3 6 6 6 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEP15297.1 - 0.00094 19.3 6.2 0.86 9.8 0.1 4.7 2 2 3 5 5 5 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 CEP15297.1 - 0.0011 19.0 0.1 2.2 8.3 0.0 3.0 2 1 1 3 3 3 2 SLIDE LSM PF01423.22 CEP15299.1 - 5e-20 71.0 0.0 6.4e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 CEP15299.1 - 3.2 8.4 13.7 6.4 7.4 13.7 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sugar_tr PF00083.24 CEP15300.1 - 1.6e-10 40.5 0.1 2e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Exo_endo_phos PF03372.23 CEP15301.1 - 0.0021 17.6 0.3 0.0063 16.0 0.3 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Protamine_P2 PF00841.19 CEP15303.1 - 0.025 15.1 2.4 0.025 15.1 2.4 2.2 2 0 0 2 2 2 0 Sperm histone P2 Pro-NT_NN PF07421.11 CEP15303.1 - 0.08 13.2 0.2 0.08 13.2 0.2 1.6 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor FAM176 PF14851.6 CEP15303.1 - 6.4 6.4 14.8 1.3 8.7 6.0 2.3 2 0 0 2 2 2 0 FAM176 family ERCC4 PF02732.15 CEP15304.1 - 4.9e-24 85.3 0.1 4.9e-24 85.3 0.1 2.4 2 0 0 2 2 2 1 ERCC4 domain SUIM_assoc PF16619.5 CEP15304.1 - 0.0088 16.1 7.4 0.0088 16.1 7.4 2.8 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 MutL PF13941.6 CEP15304.1 - 0.016 13.8 0.0 0.033 12.8 0.0 1.5 1 0 0 1 1 1 0 MutL protein Spherulin4 PF12138.8 CEP15304.1 - 0.037 13.7 0.2 0.037 13.7 0.2 1.9 2 0 0 2 2 2 0 Spherulation-specific family 4 HTH_45 PF14947.6 CEP15304.1 - 0.047 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DUF1495 PF07381.11 CEP15304.1 - 0.096 12.5 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) HHH_5 PF14520.6 CEP15304.1 - 0.16 12.6 0.1 1.9 9.2 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain WW PF00397.26 CEP15305.1 - 0.00014 21.8 8.9 0.00014 21.8 8.9 2.6 2 0 0 2 2 2 1 WW domain Sel1 PF08238.12 CEP15306.1 - 4.8e-16 58.9 5.5 2.8e-05 24.6 2.4 3.6 3 0 0 3 3 3 3 Sel1 repeat Methyltransf_25 PF13649.6 CEP15307.1 - 2.3e-15 57.0 0.0 9.7e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP15307.1 - 3.6e-14 52.9 0.0 5.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP15307.1 - 2e-12 47.6 0.0 6.1e-12 46.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP15307.1 - 4.1e-12 46.2 0.0 3.4e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP15307.1 - 1.5e-10 41.7 0.0 4.6e-10 40.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP15307.1 - 0.00015 21.3 0.0 0.00076 19.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 CEP15307.1 - 0.00022 20.0 0.0 0.0004 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 CEP15307.1 - 0.00043 19.7 0.0 0.00099 18.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CEP15307.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 CEP15307.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 CEP15307.1 - 0.03 13.8 0.1 0.19 11.2 0.0 2.2 3 0 0 3 3 3 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 CEP15307.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 CEP15307.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF2508 PF10704.9 CEP15307.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) IZUMO PF15005.6 CEP15308.1 - 0.0054 17.2 3.7 0.042 14.4 2.4 2.3 2 1 0 2 2 2 1 Izumo sperm-egg fusion, Ig domain-associated MIT PF04212.18 CEP15308.1 - 0.23 11.6 4.3 0.2 11.7 0.5 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF4972 PF16342.5 CEP15308.1 - 0.27 10.9 2.2 3.5 7.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Vir_act_alpha_C PF10400.9 CEP15308.1 - 0.39 11.4 4.1 6.1 7.6 0.2 2.7 2 0 0 2 2 2 0 Virulence activator alpha C-term Lipoprotein_6 PF01441.19 CEP15308.1 - 0.95 9.5 5.1 3.6 7.6 1.0 2.3 2 0 0 2 2 2 0 Lipoprotein Phage_GP20 PF06810.11 CEP15308.1 - 1.7 8.4 9.1 0.2 11.4 4.3 2.0 2 1 0 2 2 2 0 Phage minor structural protein GP20 BRCC36_C PF18110.1 CEP15308.1 - 3.1 8.0 6.4 9.1 6.5 0.0 3.2 3 0 0 3 3 3 0 BRCC36 C-terminal helical domain SseC PF04888.12 CEP15308.1 - 6.6 6.2 7.8 0.73 9.4 2.1 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family NDC10_II PF16787.5 CEP15309.1 - 5.8e-16 58.4 0.1 7.3e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Presenilin PF01080.17 CEP15311.1 - 3 6.5 3.8 3.5 6.3 3.8 1.1 1 0 0 1 1 1 0 Presenilin GCR1_C PF12550.8 CEP15312.1 - 5.2e-18 65.1 1.3 1e-17 64.2 0.3 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 CEP15312.1 - 1e-08 34.6 0.0 3.5e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HD_assoc PF13286.6 CEP15312.1 - 0.0061 17.1 0.1 8.1 7.1 0.0 2.8 3 0 0 3 3 3 2 Phosphohydrolase-associated domain Snf7 PF03357.21 CEP15313.1 - 4.7e-31 107.7 22.6 4.7e-31 107.7 22.6 1.7 1 1 1 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 CEP15313.1 - 0.085 13.5 3.0 0.095 13.3 0.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein HlyD_2 PF12700.7 CEP15313.1 - 0.23 10.2 12.5 0.39 9.4 12.5 1.5 1 1 0 1 1 1 0 HlyD family secretion protein Med26 PF08711.11 CEP15313.1 - 7.6 6.6 7.0 31 4.7 0.8 3.1 3 0 0 3 3 3 0 TFIIS helical bundle-like domain CEP19 PF14933.6 CEP15313.1 - 9.5 6.5 14.3 1.6 9.0 10.0 1.9 2 1 0 2 2 2 0 CEP19-like protein zf-C2H2_2 PF12756.7 CEP15314.1 - 5.7e-10 39.4 21.5 0.00028 21.2 4.7 4.6 3 2 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CEP15314.1 - 2.2e-05 24.7 42.6 0.039 14.3 3.5 6.0 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP15314.1 - 2.7e-05 24.3 51.7 0.0022 18.2 0.8 6.5 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP15314.1 - 0.0002 22.0 57.3 0.0073 17.1 1.8 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP15314.1 - 0.0087 16.5 2.8 0.0087 16.5 2.8 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-BED PF02892.15 CEP15314.1 - 0.014 15.4 6.4 6.7 6.8 0.1 4.7 4 0 0 4 4 4 0 BED zinc finger zf_C2H2_ZHX PF18387.1 CEP15314.1 - 0.027 14.1 26.6 0.054 13.1 1.2 5.7 6 0 0 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain 3-dmu-9_3-mt PF06983.13 CEP15314.1 - 0.13 12.8 0.0 0.56 10.8 0.0 2.1 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase CENP-B_dimeris PF09026.10 CEP15314.1 - 4.8 7.6 8.1 14 6.2 8.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SET PF00856.28 CEP15315.1 - 5.8e-07 30.1 0.1 0.016 15.6 0.0 2.9 1 1 1 2 2 2 2 SET domain TPR_6 PF13174.6 CEP15315.1 - 0.16 12.7 0.1 8.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 CEP15316.1 - 3.4e-11 42.8 0.0 9.3e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP15316.1 - 3.9e-08 33.0 0.0 2.3e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 CEP15316.1 - 0.0057 17.0 10.6 14 6.3 0.0 6.6 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) Aa_trans PF01490.18 CEP15317.1 - 7e-80 268.7 35.2 8.3e-80 268.5 35.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein VIT1 PF01988.19 CEP15317.1 - 0.0059 16.5 0.1 0.0059 16.5 0.1 2.9 2 1 0 2 2 2 1 VIT family Sec20 PF03908.13 CEP15317.1 - 0.16 11.9 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 Sec20 Mito_carr PF00153.27 CEP15318.1 - 2.3e-26 91.5 6.8 5.4e-12 45.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SUR7 PF06687.12 CEP15319.1 - 1e-16 61.2 17.9 1.4e-16 60.8 17.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Adeno_E3_CR2 PF02439.15 CEP15319.1 - 3.4 7.5 10.7 3.1 7.6 0.1 2.8 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Clc-like PF07062.12 CEP15319.1 - 4.4 6.7 9.6 8.3 5.8 9.6 1.5 1 1 0 1 1 1 0 Clc-like Ribonuc_red_lgC PF02867.15 CEP15320.1 - 1.4e-156 522.2 0.0 1.8e-156 521.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CEP15320.1 - 1.3e-16 60.3 0.1 3.5e-16 59.0 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CEP15320.1 - 1.8e-12 47.7 0.7 6.8e-12 45.8 0.0 2.5 3 0 0 3 3 3 1 ATP cone domain DDE_1 PF03184.19 CEP15320.1 - 0.07 12.8 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease F-box-like PF12937.7 CEP15321.1 - 1.1e-05 25.2 0.0 6.8e-05 22.7 0.0 2.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP15321.1 - 2.1e-05 24.2 0.8 5.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 CEP15322.1 - 1.8e-52 178.4 34.1 1.8e-52 178.4 34.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP15322.1 - 2e-13 50.0 8.4 2e-13 50.0 8.4 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 CEP15322.1 - 0.0058 15.1 0.1 0.0058 15.1 0.1 1.9 3 0 0 3 3 3 1 Transmembrane secretion effector TRM13 PF05206.14 CEP15323.1 - 4.1e-61 206.8 8.2 6.9e-61 206.1 8.2 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Ribosomal_S2 PF00318.20 CEP15324.1 - 1.1e-27 96.7 0.9 1.1e-13 50.9 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CEP15324.1 - 4.3e-07 31.2 11.5 7.5e-07 30.4 11.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PhoLip_ATPase_C PF16212.5 CEP15325.1 - 1.2e-66 225.0 36.1 1.2e-66 225.0 36.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP15325.1 - 2.7e-22 78.2 0.3 2.7e-22 78.2 0.3 3.2 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEP15325.1 - 4.8e-11 43.3 0.0 4.2e-05 23.9 0.0 3.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP15325.1 - 4.8e-11 42.6 0.0 4.3e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEP15325.1 - 4.1e-07 29.7 8.9 1.9e-06 27.5 0.0 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP15325.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.9 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase DUF1604 PF07713.13 CEP15325.1 - 0.23 11.3 1.4 1.2 9.0 1.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) F-box PF00646.33 CEP15326.1 - 0.00067 19.5 0.1 0.0017 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP15326.1 - 0.012 15.4 0.2 0.023 14.6 0.2 1.5 1 0 0 1 1 1 0 F-box-like DASH_Dad1 PF08649.10 CEP15327.1 - 8.7e-10 38.6 0.5 1.3e-09 38.1 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 GCN5L1 PF06320.13 CEP15327.1 - 0.034 14.3 0.4 0.034 14.3 0.4 1.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) V_ATPase_I PF01496.19 CEP15327.1 - 0.97 7.3 5.6 1.1 7.1 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIIE PF07228.12 CEP15328.1 - 1.9e-15 57.3 0.0 3.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CEP15328.1 - 2.1e-07 30.8 0.5 4.3e-07 29.8 0.0 1.7 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 CEP15328.1 - 0.00077 19.2 2.1 0.27 10.8 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C Ran-binding PF05508.11 CEP15328.1 - 0.19 10.7 0.8 0.29 10.1 0.8 1.2 1 0 0 1 1 1 0 RanGTP-binding protein MFS_1 PF07690.16 CEP15329.1 - 1.2e-31 109.9 29.4 1.2e-31 109.9 29.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 CEP15329.1 - 2.9 8.4 5.6 8.2 7.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MgtE PF01769.16 CEP15330.1 - 3.7e-41 140.4 23.5 2.9e-25 89.0 4.5 3.3 3 0 0 3 3 3 2 Divalent cation transporter Phage_holin_3_3 PF16083.5 CEP15330.1 - 0.0039 17.3 0.3 0.0039 17.3 0.3 2.7 3 0 0 3 3 3 1 LydA holin phage, holin superfamily III ECH_2 PF16113.5 CEP15331.1 - 1.4e-102 343.7 0.0 2e-102 343.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEP15331.1 - 4.8e-24 85.0 0.0 5.7e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Mt_ATP-synt_B PF05405.14 CEP15331.1 - 0.015 14.9 0.2 0.027 14.1 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RF-1 PF00472.20 CEP15332.1 - 1.3e-21 76.6 5.4 4.2e-21 75.0 0.9 2.2 2 0 0 2 2 2 2 RF-1 domain DnaJ PF00226.31 CEP15332.1 - 2.9e-17 62.5 0.5 5.7e-17 61.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CEP15332.1 - 5.9e-10 38.7 0.1 1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 CSL zinc finger HTH_28 PF13518.6 CEP15333.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PAD_porph PF04371.15 CEP15334.1 - 0.019 14.3 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase IL34 PF15036.6 CEP15334.1 - 0.024 14.7 0.2 0.05 13.6 0.2 1.5 1 0 0 1 1 1 0 Interleukin 34 SR-25 PF10500.9 CEP15334.1 - 0.56 9.8 6.5 0.85 9.2 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CTP_transf_like PF01467.26 CEP15337.1 - 8.7e-30 103.8 0.0 1.4e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 CEP15337.1 - 0.013 15.7 0.1 0.058 13.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5639) DUF5499 PF17603.2 CEP15337.1 - 0.075 13.6 0.1 0.23 12.1 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5499) CybS PF05328.12 CEP15338.1 - 2.4e-33 114.6 0.2 2.8e-33 114.4 0.2 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DASH_Dad1 PF08649.10 CEP15339.1 - 2.3e-14 53.3 0.4 3e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 CEP15339.1 - 0.00074 19.4 0.2 0.001 19.0 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Duo1 PF08651.10 CEP15339.1 - 0.0094 15.7 0.3 0.019 14.8 0.1 1.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 FlaG PF03646.15 CEP15339.1 - 0.019 15.1 0.3 0.026 14.7 0.3 1.3 1 1 0 1 1 1 0 FlaG protein EMP24_GP25L PF01105.24 CEP15339.1 - 0.029 14.3 0.3 0.033 14.1 0.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Peptidase_M26_C PF07580.14 CEP15339.1 - 0.034 12.7 0.3 0.038 12.5 0.3 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region KxDL PF10241.9 CEP15339.1 - 0.037 14.3 0.2 0.061 13.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein Rx_N PF18052.1 CEP15339.1 - 0.047 14.0 0.1 0.072 13.4 0.1 1.3 1 0 0 1 1 1 0 Rx N-terminal domain DUF3037 PF11236.8 CEP15339.1 - 0.058 13.8 0.1 0.064 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) SPA PF08616.10 CEP15340.1 - 3.9e-37 126.7 0.0 8.1e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CEP15340.1 - 1.7e-20 73.8 12.7 7e-20 71.9 0.1 2.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 CEP15340.1 - 2.1e-08 33.2 8.3 0.00023 20.0 0.0 4.2 2 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 CEP15340.1 - 2.4e-06 27.4 0.7 0.084 12.4 0.0 3.6 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) TFIIA PF03153.13 CEP15340.1 - 0.00012 22.3 16.8 0.0002 21.5 16.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 CEP15340.1 - 0.00062 20.1 5.3 0.0011 19.4 5.3 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PPL5 PF18168.1 CEP15340.1 - 0.0088 15.4 2.0 0.015 14.7 2.0 1.3 1 0 0 1 1 1 1 Prim-pol family 5 DUF2722 PF10846.8 CEP15340.1 - 0.0095 14.9 15.3 0.015 14.3 15.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 CEP15340.1 - 0.037 14.7 11.4 0.092 13.4 11.4 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CEP15340.1 - 0.044 13.4 27.7 0.087 12.4 27.7 1.4 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 CEP15340.1 - 0.045 13.9 5.1 0.098 12.8 5.1 1.6 1 0 0 1 1 1 0 DDHD domain DUF1645 PF07816.11 CEP15340.1 - 0.16 12.5 4.7 0.31 11.6 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Roughex PF06020.11 CEP15340.1 - 0.25 10.4 8.2 0.42 9.7 8.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein OmpH PF03938.14 CEP15340.1 - 0.27 11.6 19.5 0.66 10.3 19.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Adaptin_binding PF10199.9 CEP15340.1 - 0.6 10.7 9.3 0.11 13.2 4.8 2.0 3 0 0 3 3 1 0 Alpha and gamma adaptin binding protein p34 Suf PF05843.14 CEP15340.1 - 0.63 10.0 10.4 1.3 8.9 10.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SID-1_RNA_chan PF13965.6 CEP15340.1 - 0.97 7.8 3.8 1.4 7.3 3.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.13 CEP15340.1 - 1.1 9.0 6.6 2.1 8.1 6.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 CEP15340.1 - 1.2 7.8 10.5 2 7.1 10.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CEP15340.1 - 2 7.7 13.8 0.27 10.5 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CEP15340.1 - 2.7 8.0 4.4 5 7.1 4.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HEAT_EZ PF13513.6 CEP15340.1 - 3.6 8.2 0.0 3.6 8.2 0.0 3.2 4 0 0 4 4 2 0 HEAT-like repeat DUF4834 PF16118.5 CEP15340.1 - 4.5 8.3 10.9 14 6.8 10.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FlaG PF03646.15 CEP15340.1 - 5.1 7.3 16.4 8.2 6.7 14.3 2.4 2 0 0 2 2 2 0 FlaG protein Peptidase_S49_N PF08496.10 CEP15340.1 - 7 6.7 8.9 3.3 7.8 5.6 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Skp1_POZ PF03931.15 CEP15341.1 - 1.3e-27 95.8 1.2 4.2e-27 94.1 0.9 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 CEP15341.1 - 1e-26 92.8 0.5 1e-26 92.8 0.5 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain CofC PF01983.16 CEP15341.1 - 0.036 13.2 1.1 0.047 12.9 1.1 1.1 1 0 0 1 1 1 0 Guanylyl transferase CofC like Trnau1ap PF17654.1 CEP15341.1 - 0.13 13.2 0.8 0.22 12.4 0.6 1.5 1 1 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins ATP_bind_1 PF03029.17 CEP15342.1 - 1.9e-70 237.4 0.9 3.2e-70 236.7 0.9 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CEP15342.1 - 1.8e-06 27.6 0.4 8.3e-05 22.2 0.4 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CEP15342.1 - 2.7e-05 23.5 3.1 0.0022 17.2 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit AAA_16 PF13191.6 CEP15342.1 - 9.9e-05 22.8 0.0 0.00022 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CEP15342.1 - 0.00016 21.5 0.4 0.00049 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CEP15342.1 - 0.00016 20.8 0.0 0.31 10.0 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CEP15342.1 - 0.00022 20.8 0.0 0.0066 16.0 0.0 2.8 2 1 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.6 CEP15342.1 - 0.00024 21.3 0.0 0.00085 19.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 CEP15342.1 - 0.00034 20.3 0.0 1 8.9 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CEP15342.1 - 0.0007 18.9 0.3 0.003 16.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 CEP15342.1 - 0.00074 19.8 0.0 0.0025 18.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 CEP15342.1 - 0.0014 18.6 0.0 0.0076 16.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CEP15342.1 - 0.0015 18.5 0.0 0.0045 16.9 0.0 1.8 2 0 0 2 2 1 1 NACHT domain AAA_7 PF12775.7 CEP15342.1 - 0.0021 17.6 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Arf PF00025.21 CEP15342.1 - 0.0036 16.8 1.3 0.62 9.5 0.0 3.1 3 2 0 3 3 3 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CEP15342.1 - 0.0045 16.7 0.1 0.18 11.5 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 CEP15342.1 - 0.006 16.2 0.0 0.038 13.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CEP15342.1 - 0.0078 16.7 3.2 2.2 8.7 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CEP15342.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 CEP15342.1 - 0.013 16.0 0.7 0.27 11.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 CEP15342.1 - 0.014 15.7 0.0 0.047 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CEP15342.1 - 0.015 15.3 1.5 0.066 13.1 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PRK PF00485.18 CEP15342.1 - 0.024 14.4 0.0 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 CEP15342.1 - 0.05 13.3 0.6 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.20 CEP15342.1 - 0.055 13.4 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase IMS PF00817.20 CEP15342.1 - 0.097 12.7 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 impB/mucB/samB family CLP1_P PF16575.5 CEP15342.1 - 0.12 12.2 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 CEP15342.1 - 0.16 12.2 1.9 2.6 8.3 0.0 3.0 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CEP15342.1 - 0.21 10.9 1.4 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family PP2C_C PF07830.13 CEP15342.1 - 0.31 11.5 3.4 1 9.9 3.4 1.8 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Fumerase PF05681.14 CEP15342.1 - 0.33 10.3 1.8 1.8 7.9 1.1 2.0 2 0 0 2 2 2 0 Fumarate hydratase (Fumerase) SRPRB PF09439.10 CEP15342.1 - 0.42 10.0 3.8 2.3 7.6 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit CENP-B_dimeris PF09026.10 CEP15342.1 - 0.51 10.8 10.1 1.1 9.7 10.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.12 CEP15342.1 - 0.77 9.2 3.5 1.1 8.7 3.5 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF1168 PF06658.12 CEP15342.1 - 1.8 8.4 13.8 1.1 9.1 11.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) NOA36 PF06524.12 CEP15342.1 - 2.9 7.1 8.8 4.3 6.6 8.8 1.1 1 0 0 1 1 1 0 NOA36 protein Aldedh PF00171.22 CEP15343.1 - 7.4e-178 591.8 0.0 8.5e-178 591.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP15343.1 - 0.052 13.0 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PALP PF00291.25 CEP15344.1 - 4.7e-58 196.9 1.5 3.3e-57 194.1 1.5 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FancD2 PF14631.6 CEP15345.1 - 5.6e-174 580.8 43.3 1.3e-171 573.0 24.8 5.4 2 1 1 3 3 3 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 CEP15345.1 - 0.034 14.4 3.5 0.98 9.7 0.0 3.7 3 0 0 3 3 3 0 FANCI solenoid 2 P3A PF08727.11 CEP15345.1 - 0.11 11.9 0.1 0.43 10.0 0.1 2.1 1 0 0 1 1 1 0 Poliovirus 3A protein like BSP_II PF05432.11 CEP15345.1 - 2.7 7.6 28.4 0.0093 15.7 19.0 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.13 CEP15345.1 - 3.4 7.5 21.4 0.55 10.2 17.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HLH PF00010.26 CEP15346.1 - 7.7e-19 67.4 0.0 1.4e-17 63.4 0.0 3.1 4 1 0 4 4 4 1 Helix-loop-helix DNA-binding domain Integrase_H2C2 PF17921.1 CEP15347.1 - 9e-13 48.1 0.1 1.5e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP15347.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 CEP15350.1 - 1.8e-10 40.9 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CEP15350.1 - 0.00012 21.8 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Filament PF00038.21 CEP15351.1 - 0.0062 16.2 12.2 0.0062 16.2 12.2 3.7 2 1 1 3 3 3 2 Intermediate filament protein LegC3_N PF18654.1 CEP15351.1 - 7.9 5.6 48.9 0.33 10.1 9.5 3.5 1 1 2 3 3 3 0 LegC3 N-terminal coiled-coil domain Fungal_trans PF04082.18 CEP15352.1 - 6e-08 32.0 0.6 9.6e-08 31.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP15352.1 - 6.1e-08 32.7 7.8 1.2e-07 31.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CEP15353.1 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP15353.1 - 0.053 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 CEP15353.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ank_5 PF13857.6 CEP15353.1 - 0.15 12.4 0.2 3 8.3 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NUDIX PF00293.28 CEP15354.1 - 1.6e-17 63.8 0.1 2e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CEP15354.1 - 0.00024 21.0 0.1 0.00039 20.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain SRP68 PF16969.5 CEP15355.1 - 5.5e-116 388.8 18.0 9e-115 384.8 18.0 2.0 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 zf-RING_2 PF13639.6 CEP15355.1 - 6.7e-07 29.5 2.1 6.7e-07 29.5 2.1 2.1 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 CEP15355.1 - 1.9e-05 24.9 4.5 4.7e-05 23.6 4.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP15355.1 - 5.2e-05 23.0 1.7 5.2e-05 23.0 1.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP15355.1 - 8.2e-05 22.4 3.8 0.00023 20.9 3.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP15355.1 - 0.00015 21.6 3.6 0.00037 20.4 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP15355.1 - 0.00056 19.9 1.2 0.0015 18.5 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CEP15355.1 - 0.0055 16.4 1.7 0.0055 16.4 1.7 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-Nse PF11789.8 CEP15355.1 - 0.019 14.8 0.8 0.038 13.8 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CEP15355.1 - 0.059 13.2 0.9 0.17 11.7 0.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CEP15355.1 - 0.099 12.7 5.0 0.14 12.2 2.9 2.3 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 CEP15355.1 - 0.15 12.3 3.7 1.6 9.0 3.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CEP15355.1 - 0.17 11.9 4.0 0.56 10.3 4.0 1.9 1 1 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CEP15355.1 - 0.26 11.0 8.2 0.031 13.9 2.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CEP15355.1 - 1.2 9.1 4.9 0.24 11.3 1.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Arrestin_N PF00339.29 CEP15356.1 - 6e-08 32.9 0.2 2.2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP15356.1 - 0.039 14.4 0.2 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.25 CEP15357.1 - 9.7e-71 238.2 0.0 1.3e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15357.1 - 5.5e-35 120.9 0.0 8.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15357.1 - 4.5e-05 22.9 0.0 8.2e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like MAPEG PF01124.18 CEP15358.1 - 0.0068 16.3 5.8 0.0081 16.1 5.8 1.2 1 1 0 1 1 1 1 MAPEG family DUF3302 PF11742.8 CEP15358.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3302) DUF2207 PF09972.9 CEP15358.1 - 0.7 8.6 7.1 0.47 9.2 5.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM208_SND2 PF05620.11 CEP15358.1 - 1.4 8.6 5.9 2.7 7.7 4.7 1.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Glucan_synthase PF02364.15 CEP15359.1 - 0 1170.3 0.4 0 1169.3 0.4 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEP15359.1 - 1.2e-31 109.7 1.6 1.4e-29 103.0 1.6 2.7 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 GPI-anchored PF10342.9 CEP15360.1 - 4.5e-10 40.1 1.5 4.5e-10 40.1 1.5 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_S9 PF00380.19 CEP15361.1 - 1.2e-31 109.8 0.1 1.3e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L27A PF00828.19 CEP15362.1 - 7.6e-21 75.1 0.8 7.9e-21 75.1 0.3 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A eIF-6 PF01912.18 CEP15363.1 - 1.3e-83 279.2 0.4 1.3e-83 279.2 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family DnaJ PF00226.31 CEP15364.1 - 3.8e-12 46.1 6.4 6.9e-10 38.9 1.9 3.5 3 1 0 3 3 3 2 DnaJ domain RRM_1 PF00076.22 CEP15364.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serinc PF03348.15 CEP15364.1 - 0.21 10.5 1.3 0.32 9.9 1.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALMT PF11744.8 CEP15364.1 - 0.36 9.6 5.9 0.58 8.9 5.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CEP15364.1 - 0.46 9.5 1.4 0.8 8.7 1.4 1.3 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 CEP15364.1 - 1.2 8.8 2.8 2.4 7.9 2.8 1.5 1 0 0 1 1 1 0 Connexin HSP70 PF00012.20 CEP15365.1 - 3.2e-05 22.3 0.0 4.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP15365.1 - 0.073 11.9 0.0 0.4 9.4 0.0 2.1 3 0 0 3 3 3 0 MreB/Mbl protein HSP70 PF00012.20 CEP15366.1 - 0.001 17.4 0.0 0.036 12.2 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CEP15366.1 - 0.0047 15.8 0.0 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein GCR1_C PF12550.8 CEP15368.1 - 1.1e-09 38.4 0.3 1.7e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes CDPS PF16715.5 CEP15368.1 - 0.0003 20.5 0.1 0.00035 20.3 0.1 1.1 1 0 0 1 1 1 1 Cyclodipeptide synthase NDC10_II PF16787.5 CEP15369.1 - 0.0022 17.1 0.0 0.007 15.5 0.0 1.6 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Pyr_redox_2 PF07992.14 CEP15370.1 - 6e-50 170.1 0.0 7.6e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP15370.1 - 2.9e-11 43.8 0.0 4.7e-10 39.9 0.0 2.7 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP15370.1 - 7.2e-05 22.2 0.1 0.21 10.8 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP15370.1 - 0.025 13.3 0.4 0.27 9.9 0.0 2.2 1 1 1 2 2 2 0 HI0933-like protein TPPII_N PF12583.8 CEP15370.1 - 0.098 13.2 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal NAD_binding_9 PF13454.6 CEP15370.1 - 0.39 10.7 1.6 11 6.0 0.8 2.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding SKA2 PF16740.5 CEP15371.1 - 0.0025 17.6 6.2 0.048 13.4 1.3 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 CEP15371.1 - 0.0078 15.1 12.4 0.25 10.2 4.9 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein CALCOCO1 PF07888.11 CEP15371.1 - 0.028 13.3 10.3 0.034 13.0 10.3 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 CEP15371.1 - 0.042 14.1 13.6 0.043 14.0 3.7 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) KxDL PF10241.9 CEP15371.1 - 0.046 14.0 5.8 0.067 13.5 0.3 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein GAS PF13851.6 CEP15371.1 - 0.046 13.1 11.7 0.075 12.4 2.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CEP15371.1 - 0.07 13.2 10.0 0.037 14.0 1.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 CEP15371.1 - 0.094 11.9 13.2 0.46 9.6 13.2 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 CEP15371.1 - 0.26 11.3 8.1 0.11 12.5 3.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 CEP15371.1 - 0.27 11.0 3.2 3.9 7.3 0.2 2.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Rho_Binding PF08912.11 CEP15371.1 - 0.28 12.0 6.2 0.76 10.6 0.4 2.8 2 0 0 2 2 2 0 Rho Binding Nsp1_C PF05064.13 CEP15371.1 - 0.35 10.7 8.7 0.34 10.7 0.8 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3450 PF11932.8 CEP15371.1 - 0.4 10.0 11.8 0.059 12.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 CEP15371.1 - 0.56 10.9 8.1 98 3.7 8.1 2.7 1 1 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 CEP15371.1 - 0.67 9.1 7.0 2.9 7.1 0.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein Med21 PF11221.8 CEP15371.1 - 0.76 10.0 11.3 0.15 12.3 4.6 2.5 1 1 2 3 3 3 0 Subunit 21 of Mediator complex XhlA PF10779.9 CEP15371.1 - 0.84 9.9 5.4 9.7 6.5 1.6 3.0 2 1 0 2 2 2 0 Haemolysin XhlA BRE1 PF08647.11 CEP15371.1 - 1.1 9.4 9.7 0.29 11.2 1.7 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF2408 PF10303.9 CEP15371.1 - 1.9 9.1 7.3 7.7 7.1 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF724 PF05266.14 CEP15371.1 - 2.9 7.7 9.0 2.7 7.8 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RecG_N PF17190.4 CEP15371.1 - 3.1 8.6 5.9 14 6.5 0.6 2.8 1 1 2 3 3 3 0 RecG N-terminal helical domain DUF745 PF05335.13 CEP15371.1 - 6.9 6.3 7.3 7.6 6.2 2.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF745) S36_mt PF10937.8 CEP15372.1 - 2.1e-12 48.6 3.2 2.2e-07 32.5 0.2 2.2 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial Ribonuc_L-PSP PF01042.21 CEP15373.1 - 5e-29 100.8 0.1 6.3e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyt-b5 PF00173.28 CEP15374.1 - 3.2e-17 62.4 0.0 2.3e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 CEP15374.1 - 2.3e-15 57.1 23.0 3.6e-15 56.5 23.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF1451 PF07295.11 CEP15375.1 - 0.0013 18.7 7.4 2.2 8.3 0.1 4.5 2 1 1 4 4 4 3 Zinc-ribbon containing domain DUF241 PF03087.14 CEP15375.1 - 0.011 15.6 0.3 0.032 14.1 0.3 1.7 1 0 0 1 1 1 0 Arabidopsis protein of unknown function FliG_N PF14842.6 CEP15375.1 - 0.033 14.7 1.3 27 5.4 0.2 3.9 3 2 2 5 5 5 0 FliG N-terminal domain UBA_6 PF18039.1 CEP15375.1 - 0.039 13.9 0.2 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 UBA-like domain FKBP_N PF01346.18 CEP15375.1 - 0.79 10.7 9.3 3.4 8.7 1.0 4.3 2 2 3 5 5 5 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PEX11 PF05648.14 CEP15377.1 - 2.1e-56 190.9 0.8 2.3e-56 190.7 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ribosomal_L14e PF01929.17 CEP15378.1 - 1.8e-29 102.1 5.3 3.2e-29 101.2 5.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CEP15378.1 - 0.0017 18.2 0.2 0.0027 17.6 0.2 1.3 1 0 0 1 1 1 1 KOW motif UCH PF00443.29 CEP15379.1 - 2.3e-78 263.3 1.4 2.3e-44 151.8 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CEP15379.1 - 7e-17 61.8 2.0 2e-16 60.4 0.0 2.9 2 1 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CEP15379.1 - 6e-16 58.9 1.2 1.4e-08 34.8 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CEP15379.1 - 0.00029 20.6 1.8 0.00046 19.9 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal tRNA-Thr_ED PF08915.11 CEP15379.1 - 0.099 12.7 2.2 0.43 10.6 2.2 2.1 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase HECT PF00632.25 CEP15380.1 - 6.3e-73 245.9 0.2 1.4e-72 244.8 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Phostensin_N PF13916.6 CEP15380.1 - 0.078 13.3 0.6 0.26 11.7 0.6 1.9 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal MDM31_MDM32 PF08118.11 CEP15381.1 - 7.5e-96 321.9 0.6 3.4e-48 164.6 0.0 2.4 3 0 0 3 3 3 2 Yeast mitochondrial distribution and morphology (MDM) proteins Metallophos PF00149.28 CEP15381.1 - 1.7e-16 61.3 0.0 3.4e-07 31.0 0.1 3.0 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase RVT_1 PF00078.27 CEP15385.1 - 1.3e-30 106.6 0.0 2.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP15385.1 - 1.1e-05 26.1 1.8 1.9e-05 25.3 0.3 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Terminase_5 PF06056.12 CEP15386.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) NTR PF01759.21 CEP15386.1 - 0.031 14.1 0.7 2.6 7.9 0.0 2.4 2 1 0 2 2 2 0 UNC-6/NTR/C345C module HTH_23 PF13384.6 CEP15386.1 - 0.041 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 CEP15386.1 - 0.044 13.9 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4508 PF14969.6 CEP15386.1 - 0.22 11.8 1.9 0.37 11.1 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4508) Retrotrans_gag PF03732.17 CEP15387.1 - 0.015 15.6 0.1 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.27 CEP15388.1 - 2.2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP15388.1 - 7.6e-10 38.7 0.0 1.3e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP15388.1 - 0.018 15.3 0.1 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase SCAPER_N PF16501.5 CEP15388.1 - 0.053 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum PerC PF06069.11 CEP15390.1 - 0.056 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 PerC transcriptional activator DUF5565 PF17720.1 CEP15390.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Lipase_3 PF01764.25 CEP15391.1 - 1.2e-17 64.1 0.0 2.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 CEP15391.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CEP15391.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 CEP15391.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nuc_sug_transp PF04142.15 CEP15392.1 - 3.3e-107 358.3 28.8 3.9e-68 229.9 8.0 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 CEP15392.1 - 1.2e-05 25.4 7.1 1.2e-05 25.4 7.1 3.8 3 2 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 CEP15392.1 - 0.00024 20.4 0.7 0.00024 20.4 0.7 2.5 2 1 0 2 2 2 2 UAA transporter family Peptidase_S41 PF03572.18 CEP15393.1 - 2.3e-08 33.8 0.0 5.9e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 ELP6 PF09807.9 CEP15394.1 - 4.5e-50 170.4 0.1 5.2e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 CEP15394.1 - 6.3e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 CEP15394.1 - 2.4e-05 23.8 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KaiC DUF835 PF05763.12 CEP15394.1 - 0.032 14.0 1.4 0.23 11.2 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF835) AAA_25 PF13481.6 CEP15394.1 - 0.056 13.0 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Auxin_inducible PF02519.14 CEP15395.1 - 0.0049 17.0 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 Auxin responsive protein DUF2070 PF09843.9 CEP15395.1 - 0.11 10.8 0.2 0.17 10.1 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Histone PF00125.24 CEP15396.1 - 7.6e-52 175.1 2.8 8.4e-52 175.0 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP15396.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEP15396.1 - 7.4e-05 22.8 0.4 0.00013 22.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEP15396.1 - 0.00015 22.3 1.6 0.00019 22.0 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEP15396.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP15396.1 - 0.016 15.3 0.2 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP15396.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated AA_kinase PF00696.28 CEP15397.1 - 2.7e-32 112.3 1.0 1.1e-31 110.3 0.1 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 CEP15397.1 - 2.1e-14 53.1 1.6 4.7e-10 39.1 0.3 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 CEP15397.1 - 6.1e-12 45.1 0.7 0.00019 21.1 0.1 3.1 2 0 0 2 2 2 2 ACT domain PseudoU_synth_1 PF01416.20 CEP15398.1 - 5.5e-10 39.7 0.0 4e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sas10 PF09368.10 CEP15399.1 - 1.6e-28 99.0 7.2 1.6e-28 99.0 7.2 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CEP15399.1 - 3.2e-13 50.1 1.6 2.8e-12 47.1 0.0 3.0 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Pox_VLTF3 PF04947.14 CEP15399.1 - 0.0065 16.2 1.4 0.0065 16.2 1.4 2.2 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like Bud13 PF09736.9 CEP15400.1 - 1e-48 165.5 11.2 1e-48 165.5 11.2 3.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Homeodomain PF00046.29 CEP15401.1 - 6.2e-16 58.0 1.9 6.7e-16 57.9 0.9 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CEP15401.1 - 0.0017 18.2 0.1 0.0041 17.0 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CEP15401.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain RanGAP1_C PF07834.11 CEP15401.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 RanGAP1 C-terminal domain G_glu_transpept PF01019.21 CEP15402.1 - 7.6e-173 575.9 0.0 8.7e-173 575.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 CEP15402.1 - 0.00049 19.2 0.1 0.21 10.6 0.1 2.2 2 0 0 2 2 2 2 Asparaginase Ribosomal_L11_N PF03946.14 CEP15404.1 - 3.9e-24 84.3 0.1 7.5e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CEP15404.1 - 4.4e-17 62.4 0.1 7.9e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain LsmAD PF06741.13 CEP15405.1 - 1.8e-26 92.4 0.2 1.8e-26 92.4 0.2 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CEP15405.1 - 2.6e-21 75.6 0.0 6.3e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain BIR PF00653.21 CEP15406.1 - 1.1e-27 96.5 3.6 3.4e-13 50.0 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain EamA PF00892.20 CEP15406.1 - 9.5e-24 84.1 34.3 3.8e-14 53.0 16.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP15406.1 - 0.015 14.5 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter zf-C3HC PF07967.13 CEP15406.1 - 0.016 15.2 0.3 0.26 11.3 0.0 2.7 1 1 2 3 3 3 0 C3HC zinc finger-like TPT PF03151.16 CEP15406.1 - 9.1 5.5 8.8 0.21 10.9 1.2 1.9 2 0 0 2 2 2 0 Triose-phosphate Transporter family LysM PF01476.20 CEP15407.1 - 2.8e-10 40.1 0.1 4.6e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 LysM domain Dicty_REP PF05086.12 CEP15407.1 - 0.0013 16.8 17.7 0.0017 16.4 17.7 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DDHD PF02862.17 CEP15407.1 - 0.0098 16.1 3.1 0.012 15.7 3.1 1.1 1 0 0 1 1 1 1 DDHD domain Hydin_ADK PF17213.3 CEP15407.1 - 0.082 13.2 9.7 0.12 12.7 9.7 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain TT_ORF1 PF02956.14 CEP15407.1 - 0.094 11.4 10.8 0.12 11.1 10.8 1.2 1 0 0 1 1 1 0 TT viral orf 1 EloA-BP1 PF15870.5 CEP15407.1 - 0.16 12.2 9.6 0.24 11.7 9.6 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 Membralin PF09746.9 CEP15407.1 - 0.45 9.5 3.0 0.55 9.2 3.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF572 PF04502.13 CEP15407.1 - 0.95 9.0 17.3 1.2 8.7 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sec62 PF03839.16 CEP15407.1 - 1.1 8.7 6.2 1.6 8.2 6.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.8 CEP15407.1 - 3.2 6.5 8.5 4.5 5.9 8.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4054 PF13262.6 CEP15407.1 - 3.5 7.7 7.2 1.2 9.2 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) CPSF100_C PF13299.6 CEP15407.1 - 3.6 7.7 10.1 6.2 7.0 10.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DAG_kinase_N PF14513.6 CEP15407.1 - 3.9 7.7 8.6 6.4 7.0 8.6 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SWI-SNF_Ssr4 PF08549.10 CEP15407.1 - 4.4 5.8 8.6 5.2 5.6 8.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) T3SSipB PF16535.5 CEP15409.1 - 0.033 14.7 0.1 0.055 14.0 0.1 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 CEP15409.1 - 0.074 13.1 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Helo_like_N PF17111.5 CEP15409.1 - 0.078 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Taxilin PF09728.9 CEP15409.1 - 0.08 12.1 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GCR PF02155.15 CEP15410.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucocorticoid receptor RVT_1 PF00078.27 CEP15411.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ARA70 PF12489.8 CEP15411.1 - 0.03 14.5 0.7 0.35 11.1 0.0 2.5 3 0 0 3 3 3 0 Nuclear coactivator RVT_1 PF00078.27 CEP15412.1 - 1.6e-17 63.8 0.0 3.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP15412.1 - 1e-16 61.2 0.0 8.3e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP15412.1 - 0.00063 19.8 0.2 0.0014 18.7 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP15412.1 - 0.049 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain AAA PF00004.29 CEP15413.1 - 1.2e-41 142.2 0.0 2.9e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP15413.1 - 9.6e-09 34.9 0.1 2.5e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEP15413.1 - 1.7e-05 24.8 0.1 9e-05 22.5 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEP15413.1 - 8.3e-05 22.9 0.0 0.0053 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP15413.1 - 0.00015 22.2 0.1 0.0029 18.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CEP15413.1 - 0.00022 21.4 0.0 0.00082 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CEP15413.1 - 0.00035 19.8 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CEP15413.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CEP15413.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CEP15413.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP15413.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEP15413.1 - 0.023 14.6 0.2 6.1 6.7 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CEP15413.1 - 0.031 14.6 0.0 0.096 13.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 CEP15413.1 - 0.035 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CEP15413.1 - 0.038 13.7 0.1 0.12 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 CEP15413.1 - 0.042 13.1 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CEP15413.1 - 0.057 14.0 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CEP15413.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CEP15413.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 CEP15413.1 - 0.091 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CEP15413.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEP15413.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Integrase_H2C2 PF17921.1 CEP15415.1 - 4.1e-16 58.8 0.9 9.9e-16 57.6 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP15415.1 - 8.7e-13 48.5 0.0 2.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP15415.1 - 0.0009 19.0 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Spectrin_like PF18373.1 CEP15415.1 - 0.036 14.1 1.0 15 5.7 0.2 3.9 4 0 0 4 4 4 0 Spectrin like domain Helitron_like_N PF14214.6 CEP15416.1 - 3.1e-11 43.8 0.1 4.2e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LRR_RI_capping PF18779.1 CEP15416.1 - 0.15 11.8 1.1 5 6.9 0.1 2.6 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat OppC_N PF12911.7 CEP15417.1 - 0.16 12.0 0.2 9.8 6.2 0.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Spc29 PF17082.5 CEP15420.1 - 0.059 13.2 0.1 0.077 12.8 0.1 1.3 1 1 0 1 1 1 0 Spindle Pole Component 29 rve PF00665.26 CEP15421.1 - 2.3e-16 60.0 0.0 4.3e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP15421.1 - 1.4e-08 34.7 3.3 2.8e-08 33.7 3.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Cys_box PF17869.1 CEP15421.1 - 0.058 13.5 0.8 0.15 12.2 0.2 1.9 2 0 0 2 2 2 0 Anosmin cysteine rich domain RT_RNaseH PF17917.1 CEP15422.1 - 2.7e-25 88.7 0.0 5.1e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP15422.1 - 9e-24 83.4 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 CEP15422.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Pao retrotransposon peptidase WD40 PF00400.32 CEP15423.1 - 1.5e-41 139.6 18.4 4.2e-08 33.7 0.1 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15423.1 - 2.7e-24 85.3 0.9 0.00013 22.2 0.1 6.4 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CEP15423.1 - 4.3e-07 29.7 0.2 8.1e-07 28.8 0.2 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 CEP15423.1 - 4.4e-07 30.0 0.7 0.45 10.4 0.0 3.9 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEP15423.1 - 0.00033 20.1 0.0 0.049 13.0 0.0 3.2 3 1 0 3 3 3 1 WD40-like domain BSP_II PF05432.11 CEP15423.1 - 0.062 13.0 5.3 0.094 12.4 5.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Dsh_C PF12316.8 CEP15423.1 - 0.75 10.2 6.6 1.2 9.5 6.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2589 PF11655.8 CEP15423.1 - 0.77 10.1 5.7 0.077 13.3 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2589) Dmrt1 PF12374.8 CEP15423.1 - 7.5 7.1 11.3 11 6.5 3.1 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Atg14 PF10186.9 CEP15424.1 - 4.7e-17 62.1 25.5 1.2e-14 54.2 0.0 3.8 3 1 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 NQRA PF05896.11 CEP15424.1 - 0.028 13.8 0.1 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Roughex PF06020.11 CEP15424.1 - 0.61 9.1 5.0 1.8 7.6 4.2 2.0 2 0 0 2 2 2 0 Drosophila roughex protein Sel1 PF08238.12 CEP15425.1 - 2.2e-32 110.7 26.6 6.4e-08 33.0 1.1 5.7 6 0 0 6 6 6 5 Sel1 repeat DUF4142 PF13628.6 CEP15425.1 - 0.066 13.5 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) ATP-synt_G PF04718.15 CEP15425.1 - 0.13 13.1 0.2 0.62 10.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit MMtag PF10159.9 CEP15425.1 - 0.13 12.5 0.7 0.45 10.8 0.1 2.2 2 0 0 2 2 2 0 Multiple myeloma tumor-associated FYRN PF05964.14 CEP15426.1 - 2.1e-17 62.7 1.3 2.1e-17 62.7 1.3 2.0 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.14 CEP15426.1 - 3.8e-13 49.4 0.0 1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus Glycos_transf_1 PF00534.20 CEP15428.1 - 1.7e-29 102.6 0.0 4.2e-29 101.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP15428.1 - 4.5e-24 85.4 0.0 2e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEP15428.1 - 9.4e-22 77.8 0.1 1.5e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CEP15428.1 - 1.1e-08 35.7 0.0 1.9e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CEP15428.1 - 0.00018 21.9 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acetyltransf_9 PF13527.7 CEP15428.1 - 0.16 12.0 0.0 0.96 9.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Reprolysin_5 PF13688.6 CEP15429.1 - 3.2e-30 105.8 0.7 3.2e-30 105.8 0.7 3.6 4 0 0 4 4 4 2 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEP15429.1 - 5e-28 98.2 4.3 1e-26 93.8 4.3 2.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CEP15429.1 - 8.9e-28 97.5 15.9 5e-27 95.1 8.8 3.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CEP15429.1 - 1.5e-14 54.6 25.8 1.5e-14 54.6 25.8 4.7 5 1 0 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 CEP15429.1 - 2.6e-10 40.9 2.1 3.4e-10 40.5 0.0 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CEP15429.1 - 7.8e-07 29.4 0.0 7.8e-07 29.4 0.0 2.1 3 0 0 3 3 3 1 Reprolysin family propeptide SUIM_assoc PF16619.5 CEP15429.1 - 0.5 10.5 10.1 0.23 11.6 1.3 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Biopterin_H PF00351.21 CEP15430.1 - 1.8e-166 553.1 0.0 2.2e-166 552.9 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 CEP15430.1 - 0.0035 17.1 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain MFS_1 PF07690.16 CEP15431.1 - 5.5e-41 140.7 41.3 1.2e-40 139.5 41.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP15431.1 - 9.9e-15 54.3 16.4 9.9e-15 54.3 16.4 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CEP15431.1 - 3.5e-10 38.9 20.7 4.7e-10 38.5 20.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CBM_21 PF03370.13 CEP15432.1 - 1.4e-25 89.7 4.6 4.9e-25 87.9 1.3 2.3 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEP15432.1 - 8e-11 42.4 1.1 2.1e-10 41.0 1.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Homeobox_KN PF05920.11 CEP15433.1 - 6.4e-17 61.2 2.0 6.4e-17 61.2 2.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CEP15433.1 - 1.1e-05 25.2 2.6 1.5e-05 24.8 0.8 2.1 2 0 0 2 2 2 1 Homeodomain Myc_N PF01056.18 CEP15433.1 - 0.0019 18.2 5.9 0.0025 17.8 5.9 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Spore_coat_CotO PF14153.6 CEP15433.1 - 0.005 16.8 8.1 0.0079 16.1 8.1 1.4 1 0 0 1 1 1 1 Spore coat protein CotO Merozoite_SPAM PF07133.11 CEP15433.1 - 0.0071 16.4 14.7 0.012 15.7 14.7 1.3 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 CEP15433.1 - 0.012 13.9 8.9 0.015 13.6 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CEP15433.1 - 0.023 12.8 9.9 0.033 12.3 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi 30K_MP_C_Ter PF11330.8 CEP15433.1 - 0.071 12.4 1.5 0.11 11.9 1.5 1.2 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins GAGA_bind PF06217.12 CEP15433.1 - 0.1 12.9 3.6 0.15 12.3 3.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CEP15433.1 - 0.28 11.0 7.6 0.46 10.3 7.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTPRCAP PF15713.5 CEP15433.1 - 0.85 9.9 12.2 1.5 9.1 12.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Importin_rep_6 PF18829.1 CEP15433.1 - 1.2 9.3 4.9 0.45 10.7 1.7 2.0 3 0 0 3 3 3 0 Importin repeat 6 Presenilin PF01080.17 CEP15433.1 - 3.3 6.4 6.6 4.1 6.1 6.6 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 CEP15433.1 - 3.4 8.1 8.4 5.8 7.3 8.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM176 PF14851.6 CEP15433.1 - 3.9 7.1 11.4 6.9 6.3 11.4 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 CEP15433.1 - 9.2 5.4 9.1 14 4.8 9.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NT5C PF06941.12 CEP15434.1 - 1.5e-09 38.0 1.5 2.3e-09 37.4 0.6 1.7 1 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.7 CEP15434.1 - 0.00023 21.6 0.4 0.0017 18.8 0.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP15434.1 - 0.0013 18.9 0.2 0.0057 16.8 0.2 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP15434.1 - 0.0069 16.7 0.1 0.071 13.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NES_C_h PF18208.1 CEP15434.1 - 0.054 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain E2_bind PF08825.10 CEP15434.1 - 0.078 13.1 0.2 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 E2 binding domain Pkinase PF00069.25 CEP15435.1 - 1.6e-71 240.8 0.0 2.7e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15435.1 - 3e-38 131.6 0.0 5.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CEP15435.1 - 2.5e-13 49.6 0.1 4.9e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CEP15435.1 - 5.8e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP15435.1 - 0.0053 16.7 0.5 0.016 15.1 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP15435.1 - 0.012 14.5 0.1 0.027 13.4 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CEP15435.1 - 0.026 14.1 0.1 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CEP15435.1 - 0.048 13.0 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThiF PF00899.21 CEP15436.1 - 6.9e-34 117.3 0.2 1.2e-33 116.5 0.2 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CEP15436.1 - 9e-10 38.9 1.4 3.6e-09 37.0 1.4 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 CEP15436.1 - 0.0012 18.6 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 CEP15436.1 - 0.0022 17.6 0.1 0.0051 16.5 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CEP15436.1 - 0.0035 17.4 0.1 0.0073 16.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CEP15436.1 - 0.0051 16.1 0.6 0.014 14.7 0.6 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CEP15436.1 - 0.05 14.2 0.7 0.67 10.6 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 CEP15436.1 - 0.052 12.8 0.1 0.088 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 CEP15436.1 - 0.061 13.2 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PX PF00787.24 CEP15437.1 - 3.2e-23 81.9 0.3 7.8e-23 80.6 0.3 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CEP15437.1 - 6.6e-07 29.1 1.3 0.011 15.3 0.4 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 CEP15437.1 - 0.0072 16.7 2.6 0.009 16.3 0.3 2.0 1 1 1 2 2 2 1 Peptidase C10 family GCP_N_terminal PF17681.1 CEP15437.1 - 0.047 13.3 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal YjfB_motility PF14070.6 CEP15437.1 - 0.12 12.5 0.9 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Putative motility protein DUF848 PF05852.11 CEP15437.1 - 0.66 10.1 4.5 1.9 8.6 4.5 1.8 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) MFS_1 PF07690.16 CEP15438.1 - 4.3e-36 124.6 35.6 6.2e-36 124.0 34.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CEP15438.1 - 2.5e-07 30.3 5.2 5.5e-07 29.2 5.2 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PRMT5 PF05185.16 CEP15439.1 - 7.4e-70 234.3 0.0 1.2e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CEP15439.1 - 5.4e-57 192.9 0.8 7.2e-57 192.5 0.8 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CEP15439.1 - 5.2e-52 176.3 0.1 9.8e-52 175.4 0.1 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PhoLip_ATPase_C PF16212.5 CEP15440.1 - 1.7e-72 244.1 32.1 1.7e-72 244.1 32.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP15440.1 - 3.9e-23 80.9 0.2 1.1e-22 79.5 0.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEP15440.1 - 4.1e-14 52.4 0.1 1.1e-12 47.8 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP15440.1 - 5.2e-12 46.5 2.0 9.1e-07 29.4 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP15440.1 - 1.4e-05 24.7 0.0 1.4e-05 24.7 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP15440.1 - 0.00064 19.5 0.1 0.005 16.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 CEP15440.1 - 0.43 10.7 9.3 2 8.6 9.3 2.2 1 0 0 1 1 1 0 C-terminus of AA_permease DUF3712 PF12505.8 CEP15441.1 - 3e-27 95.4 0.1 4.4e-17 62.5 0.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) Acyltransf_C PF16076.5 CEP15441.1 - 0.2 11.8 0.0 1.1 9.4 0.0 2.3 3 0 0 3 3 3 0 Acyltransferase C-terminus DUF5305 PF17231.2 CEP15442.1 - 0.044 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF1771 PF08590.10 CEP15443.1 - 1e-21 77.1 8.2 2.5e-21 75.8 8.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEP15443.1 - 1.6e-10 41.2 0.0 4e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Smr domain Asn_synthase PF00733.21 CEP15444.1 - 2.8e-61 208.2 0.0 3.8e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CEP15444.1 - 7.4e-40 135.7 0.0 1.4e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEP15444.1 - 5.2e-32 110.9 0.0 1e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEP15444.1 - 0.031 13.7 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Aluminium induced protein 2-oxoacid_dh PF00198.23 CEP15445.1 - 2.7e-75 252.8 0.2 4.8e-75 252.0 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CEP15445.1 - 1.3e-17 63.9 0.4 2.5e-17 62.9 0.4 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 CEP15445.1 - 1e-16 60.5 0.0 2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme RPN13_C PF16550.5 CEP15446.1 - 1.5e-31 108.9 3.0 4.8e-31 107.2 3.0 1.9 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 CEP15446.1 - 8.9e-23 80.6 0.6 1.7e-22 79.7 0.6 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Mucin PF01456.17 CEP15446.1 - 0.00017 21.6 18.3 0.00027 20.9 18.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein FAP206 PF12018.8 CEP15446.1 - 0.084 12.4 0.9 0.28 10.6 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF1180 PF06679.12 CEP15446.1 - 0.32 11.4 8.9 0.81 10.1 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Menin PF05053.13 CEP15446.1 - 6.7 5.0 6.1 16 3.7 5.0 1.9 2 0 0 2 2 2 0 Menin Cu-oxidase_3 PF07732.15 CEP15447.1 - 3.7e-34 117.3 1.2 3.7e-34 117.3 1.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 CEP15447.1 - 4.2e-26 92.0 2.6 4.5e-26 91.9 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CEP15447.1 - 8.3e-26 90.4 12.1 3.8e-25 88.2 0.4 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CEP15447.1 - 0.16 12.1 0.1 48 4.1 0.0 3.6 4 1 0 4 4 4 0 Cupredoxin-like domain YmcE_antitoxin PF15939.5 CEP15447.1 - 0.2 11.8 0.0 0.47 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system GRP PF07172.11 CEP15447.1 - 1.4 9.6 38.1 12 6.7 39.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family Pkinase PF00069.25 CEP15448.1 - 9.4e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15448.1 - 1.2e-10 41.1 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP15448.1 - 3.9e-08 32.5 0.9 7.7e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase CDC50 PF03381.15 CEP15450.1 - 7.4e-86 288.1 0.2 1.1e-85 287.6 0.2 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.10 CEP15450.1 - 1.1e-38 133.6 4.7 2.4e-37 129.2 4.7 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 CEP15450.1 - 0.00016 20.9 0.0 0.00045 19.4 0.0 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate receptor SSURE PF11966.8 CEP15450.1 - 0.035 13.9 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Fibronectin-binding repeat DUF3185 PF11381.8 CEP15450.1 - 0.74 9.9 3.1 2.8 8.0 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) MIOX PF05153.15 CEP15451.1 - 2.7e-108 361.3 6.3 3.4e-108 361.0 6.3 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CEP15451.1 - 0.0032 17.7 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 HD domain p450 PF00067.22 CEP15452.1 - 1.8e-49 168.8 0.8 1.1e-48 166.2 0.8 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF424 PF04242.13 CEP15452.1 - 0.012 15.8 0.3 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF424) Hemerythrin PF01814.23 CEP15452.1 - 0.091 13.4 1.0 0.18 12.4 1.0 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Mito_carr PF00153.27 CEP15454.1 - 3.9e-44 148.5 0.2 1.2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Ysc84 PF04366.12 CEP15455.1 - 8.8e-43 145.1 0.4 2.1e-42 143.9 0.2 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_9 PF14604.6 CEP15455.1 - 5e-14 51.9 0.0 9.2e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP15455.1 - 6.8e-13 48.0 0.1 1.8e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CEP15455.1 - 1e-09 37.9 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 CEP15455.1 - 0.044 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DDE_3 PF13358.6 CEP15456.1 - 4.7e-17 62.1 0.5 8.5e-17 61.3 0.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP15456.1 - 1.3e-16 60.6 0.7 2.9e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP15456.1 - 1.8e-07 31.7 1.4 4e-07 30.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP15456.1 - 3.8e-06 26.8 0.1 6.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP15456.1 - 0.00024 20.9 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CEP15456.1 - 0.0012 18.6 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP15456.1 - 0.0014 18.7 1.2 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 CEP15456.1 - 0.0014 18.1 0.1 0.085 12.4 0.0 3.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CEP15456.1 - 0.0037 17.0 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP15456.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP15456.1 - 0.025 14.7 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 CEP15456.1 - 0.13 12.1 0.1 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase HTH_19 PF12844.7 CEP15456.1 - 0.14 12.2 2.1 16 5.6 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Tho1_MOS11_C PF18592.1 CEP15457.1 - 0.014 15.2 0.7 0.037 13.8 0.2 2.0 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain SUIM_assoc PF16619.5 CEP15458.1 - 0.061 13.4 17.3 0.25 11.4 0.6 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Axin_b-cat_bind PF08833.10 CEP15458.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.4 2 0 0 2 2 2 0 Axin beta-catenin binding domain Metallophos PF00149.28 CEP15459.1 - 2e-21 77.4 1.1 1.1e-10 42.4 0.0 2.8 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP15459.1 - 0.11 13.0 0.0 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain SSrecog PF03531.14 CEP15461.1 - 0.02 14.8 0.3 0.029 14.3 0.3 1.3 1 1 0 1 1 1 0 Structure-specific recognition protein (SSRP1) DUF2251 PF10008.9 CEP15464.1 - 0.0087 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2251) Asp PF00026.23 CEP15466.1 - 4.1e-53 180.9 0.2 5e-53 180.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP15466.1 - 1.2e-09 38.7 0.1 7.6e-08 32.8 0.1 3.3 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEP15466.1 - 0.011 16.4 0.0 3.2 8.5 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 CEP15466.1 - 0.13 12.0 0.0 0.91 9.3 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GATA PF00320.27 CEP15467.1 - 5.7e-16 57.8 2.9 5.7e-16 57.8 2.9 1.9 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP15467.1 - 0.18 11.3 2.6 0.38 10.3 2.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Peptidase_S10 PF00450.22 CEP15468.1 - 2.4e-117 392.9 4.5 2.4e-117 392.9 4.5 1.9 2 0 0 2 2 2 1 Serine carboxypeptidase HD PF01966.22 CEP15468.1 - 1.4e-13 51.1 0.1 3.2e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 CEP15468.1 - 0.008 15.9 0.1 0.035 13.8 0.1 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Pico_P2B PF01552.17 CEP15468.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Picornavirus 2B protein Pkinase PF00069.25 CEP15469.1 - 5.2e-66 222.7 0.0 1.3e-65 221.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15469.1 - 3.7e-41 141.1 0.0 6.9e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP15469.1 - 0.00024 20.5 0.5 0.00057 19.3 0.5 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP15469.1 - 0.0018 17.6 0.0 0.0057 16.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CEP15469.1 - 0.13 12.2 3.6 1.7 8.5 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PRIMA1 PF16101.5 CEP15469.1 - 0.14 12.2 1.3 0.47 10.5 1.3 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GrpE PF01025.19 CEP15469.1 - 0.76 9.4 0.0 0.76 9.4 0.0 3.2 5 0 0 5 5 5 0 GrpE DUF5532 PF17673.1 CEP15473.1 - 0.017 15.1 0.7 0.017 15.1 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Dicty_REP PF05086.12 CEP15473.1 - 0.027 12.5 4.3 0.047 11.7 4.3 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HALZ PF02183.18 CEP15473.1 - 0.39 11.0 1.5 1.1 9.5 0.2 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Hamartin PF04388.12 CEP15473.1 - 3.1 6.4 13.2 4.5 5.8 13.2 1.2 1 0 0 1 1 1 0 Hamartin protein ErmC PF06308.11 CEP15474.1 - 0.01 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 23S rRNA methylastransferase leader peptide (ErmCL) RHH_7 PF16777.5 CEP15475.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG UvrD_C_2 PF13538.6 CEP15476.1 - 0.00025 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP15476.1 - 0.0004 18.5 0.0 0.00049 18.2 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 CEP15476.1 - 0.0047 16.2 0.1 0.0063 15.7 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase P5-ATPase PF12409.8 CEP15477.1 - 0.067 13.3 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF4686 PF15742.5 CEP15477.1 - 0.15 11.2 4.2 0.13 11.3 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) DDE_Tnp_1_7 PF13843.6 CEP15479.1 - 1.6e-18 67.2 0.0 5e-17 62.2 0.0 2.0 1 1 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CEP15479.1 - 0.00074 19.2 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 CEP15479.1 - 0.0028 17.0 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_4 PF13701.6 CEP15479.1 - 0.1 10.8 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 MSP1_C PF07462.11 CEP15480.1 - 6.5 5.3 7.4 7.8 5.1 7.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AA_permease PF00324.21 CEP15481.1 - 3.9e-126 421.4 45.1 4.9e-126 421.1 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP15481.1 - 2.1e-46 158.6 46.5 2.5e-46 158.4 46.5 1.1 1 0 0 1 1 1 1 Amino acid permease Xpo1 PF08389.12 CEP15482.1 - 7.9e-29 100.6 0.4 1.4e-27 96.6 0.2 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 CEP15482.1 - 3.9e-09 36.3 1.0 4.7e-07 29.6 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain Importin_rep PF18773.1 CEP15482.1 - 0.017 14.8 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Importin 13 repeat Mito_carr PF00153.27 CEP15483.1 - 9.9e-61 201.7 1.1 1.9e-19 69.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 CEP15483.1 - 0.0094 16.0 0.5 5.6 7.1 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3764) UQ_con PF00179.26 CEP15484.1 - 6.5e-30 103.6 0.1 1.3e-29 102.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme ATP-synt_ab PF00006.25 CEP15485.1 - 3.5e-109 363.4 0.0 5.3e-109 362.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CEP15485.1 - 2.1e-43 147.0 0.0 3.7e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CEP15485.1 - 2e-13 50.7 1.9 2e-13 50.7 1.9 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Mac PF12464.8 CEP15485.1 - 0.2 11.9 0.2 0.47 10.7 0.2 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase Polyketide_cyc2 PF10604.9 CEP15486.1 - 0.0072 16.6 0.0 0.0094 16.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LEA_2 PF03168.13 CEP15487.1 - 0.18 12.4 0.2 0.29 11.7 0.2 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF2897 PF11446.8 CEP15487.1 - 0.74 9.7 3.8 1.3 9.0 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) ApbA PF02558.16 CEP15488.1 - 2e-26 92.4 0.0 3.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CEP15488.1 - 1e-23 83.9 0.4 1.6e-23 83.3 0.4 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 CEP15488.1 - 0.0042 17.6 0.0 0.064 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 CEP15488.1 - 0.0054 16.7 0.0 0.15 12.0 0.0 2.7 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 CEP15488.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Na_sulph_symp PF00939.19 CEP15489.1 - 2.2e-95 320.5 24.8 2.5e-95 320.3 24.8 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CEP15489.1 - 2.7e-19 69.5 25.7 2e-11 43.7 6.4 2.4 1 1 1 2 2 2 2 Citrate transporter Neurokinin_B PF03823.14 CEP15489.1 - 1.2 9.2 5.1 3.8 7.6 0.0 2.9 3 0 0 3 3 3 0 Neurokinin B Pkinase PF00069.25 CEP15490.1 - 2.5e-69 233.6 0.0 6e-69 232.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15490.1 - 5.6e-43 147.1 0.0 1.5e-42 145.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP15490.1 - 3.2e-06 27.3 0.0 0.0033 17.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP15490.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP15490.1 - 0.00032 20.1 0.1 0.00071 19.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP15490.1 - 0.0008 18.5 0.1 0.0008 18.5 0.1 3.1 2 1 2 4 4 4 1 Haspin like kinase domain RIO1 PF01163.22 CEP15490.1 - 0.0051 16.4 0.0 0.02 14.5 0.1 2.0 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.20 CEP15490.1 - 0.018 14.4 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 CEP15490.1 - 0.025 13.4 0.0 0.025 13.4 0.0 2.8 2 1 0 2 2 2 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CEP15490.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ketoacyl-synt_C PF02801.22 CEP15491.1 - 3e-37 127.2 0.2 4.3e-37 126.7 0.2 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CEP15491.1 - 8e-14 51.8 0.3 3.9e-13 49.6 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 CEP15491.1 - 0.00086 19.0 0.2 0.0075 15.9 0.1 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 CEP15491.1 - 0.067 13.7 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 CEP15492.1 - 2.1e-09 37.4 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.25 CEP15493.1 - 8.7e-42 143.3 4.4 9.6e-42 143.2 1.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15493.1 - 4.1e-22 78.7 4.4 3.6e-21 75.6 0.7 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEP15493.1 - 0.00067 19.1 0.2 0.0017 17.7 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2405 PF10293.9 CEP15493.1 - 0.015 15.2 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Bac_surface_Ag PF01103.23 CEP15494.1 - 9.5e-44 150.2 3.1 1.3e-43 149.7 3.1 1.2 1 0 0 1 1 1 1 Surface antigen DUF4364 PF14277.6 CEP15494.1 - 0.031 14.0 0.6 0.047 13.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) AAA_assoc PF14363.6 CEP15494.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA POTRA PF07244.15 CEP15494.1 - 0.16 12.6 0.4 0.32 11.6 0.4 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat HMGL-like PF00682.19 CEP15496.1 - 2.2e-79 266.8 0.4 3e-79 266.3 0.4 1.2 1 0 0 1 1 1 1 HMGL-like DUF4971 PF16341.5 CEP15496.1 - 0.014 15.2 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) CAP PF00188.26 CEP15497.1 - 7e-24 85.1 3.5 1.1e-23 84.5 3.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PXA PF02194.15 CEP15498.1 - 5.3e-21 75.4 1.3 5.3e-21 75.4 1.3 2.2 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CEP15498.1 - 1.6e-19 70.5 0.7 5.3e-19 68.9 0.7 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 CEP15498.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 PX domain Kei1 PF08552.11 CEP15499.1 - 8.5e-22 78.0 20.4 4e-17 62.7 12.2 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 CEP15499.1 - 2.2 7.9 8.0 4.2 7.0 8.0 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF308 PF03729.13 CEP15499.1 - 8.7 6.8 14.1 2.9 8.3 0.9 2.5 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) AMP-binding PF00501.28 CEP15500.1 - 1e-69 235.2 0.0 1.4e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CEP15500.1 - 1.1e-68 231.2 0.0 1.6e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 CEP15500.1 - 3.3e-13 49.8 0.1 1.1e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 CEP15500.1 - 2.4e-11 43.0 0.0 7.8e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 Condensation domain Epimerase PF01370.21 CEP15500.1 - 3.4e-10 39.8 0.0 7.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CEP15500.1 - 7.7e-07 28.4 0.0 1.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CEP15500.1 - 1.7e-05 25.7 0.0 6.3e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 CEP15500.1 - 0.00063 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CEP15500.1 - 0.0012 18.8 0.0 0.014 15.3 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Tap-RNA_bind PF09162.10 CEP15501.1 - 0.031 14.1 0.3 0.09 12.6 0.0 1.8 1 1 1 2 2 2 0 Tap, RNA-binding DUF21 PF01595.20 CEP15501.1 - 0.079 12.7 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF21 PF01595.20 CEP15502.1 - 0.072 12.8 0.1 0.095 12.4 0.1 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Ribosomal_S19 PF00203.21 CEP15503.1 - 3.8e-16 58.7 0.2 8.3e-16 57.6 0.2 1.5 1 1 1 2 2 2 1 Ribosomal protein S19 Steroid_dh PF02544.16 CEP15504.1 - 4e-19 69.1 1.9 6.6e-19 68.4 1.9 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2407_C PF13373.6 CEP15504.1 - 1e-13 51.6 0.1 2.2e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 CEP15504.1 - 6.2e-11 41.9 0.1 1.1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CEP15504.1 - 1.3e-07 31.6 0.0 6.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CEP15504.1 - 2e-07 31.5 0.1 4.7e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CEP15504.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CEP15504.1 - 0.0086 16.4 0.1 0.02 15.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain VHS PF00790.19 CEP15505.1 - 1.2e-36 125.7 1.9 8.7e-31 106.7 0.0 3.2 2 2 1 4 4 4 2 VHS domain Alpha_adaptinC2 PF02883.20 CEP15505.1 - 1.3e-20 73.7 0.3 3.1e-20 72.5 0.3 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 CEP15505.1 - 4.5e-12 46.1 0.8 4.5e-12 46.1 0.8 2.5 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 CEP15505.1 - 1.7e-06 27.5 0.1 4.6e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain Ald_deCOase PF11266.8 CEP15505.1 - 0.09 12.5 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase RPAP1_C PF08620.10 CEP15505.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 RPAP1-like, C-terminal Aldedh PF00171.22 CEP15506.1 - 1.4e-135 452.4 0.0 1.6e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LZ3wCH PF18517.1 CEP15506.1 - 0.015 15.4 0.3 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain LuxC PF05893.14 CEP15506.1 - 0.046 12.8 0.6 0.082 11.9 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Peptidase_M17_N PF02789.17 CEP15506.1 - 0.41 10.5 1.8 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Shisa PF13908.6 CEP15507.1 - 0.0087 16.3 0.5 0.019 15.2 0.3 1.8 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 CEP15507.1 - 0.02 15.5 0.5 0.044 14.4 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.16 CEP15507.1 - 0.053 12.3 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ribosomal_S4e PF00900.20 CEP15508.1 - 1.8e-38 130.3 1.1 2.4e-37 126.7 0.3 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CEP15508.1 - 5e-26 90.1 0.1 8.9e-26 89.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CEP15508.1 - 2.9e-15 56.1 2.1 8.4e-15 54.6 2.4 1.6 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CEP15508.1 - 6.7e-07 28.9 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CEP15508.1 - 7e-05 22.6 7.4 0.00021 21.1 5.0 3.0 3 1 0 3 3 3 1 KOW motif Ins134_P3_kin PF05770.11 CEP15509.1 - 9.6e-27 93.8 0.4 9.6e-27 93.8 0.4 1.5 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 CEP15509.1 - 2.7e-14 53.3 0.1 5.8e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATP-grasp PF02222.22 CEP15509.1 - 0.051 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.25 CEP15511.1 - 1.8e-73 247.2 0.0 2.5e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15511.1 - 4.7e-48 163.7 0.0 7.3e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP15511.1 - 1e-22 80.2 0.1 3.8e-22 78.4 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CEP15511.1 - 1e-07 31.6 0.1 2.5e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP15511.1 - 4.2e-05 22.5 0.0 8.5e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP15511.1 - 0.00035 19.6 0.9 0.0012 17.9 0.9 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP15511.1 - 0.018 14.4 0.4 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEP15511.1 - 0.028 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DSHCT PF08148.12 CEP15511.1 - 0.16 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 CEP15511.1 - 0.75 9.7 4.4 1.1 9.1 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 CEP15512.1 - 1.3e-31 110.2 0.0 1.8e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP15512.1 - 1.3e-25 90.1 0.0 3.3e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEP15512.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 CEP15512.1 - 0.06 12.2 0.0 8.5 5.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family SIS PF01380.22 CEP15513.1 - 4.1e-23 81.7 0.0 9.2e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 CEP15513.1 - 4e-07 30.1 0.0 0.0029 17.6 0.0 2.6 1 1 1 2 2 2 2 SIS domain CBS PF00571.28 CEP15513.1 - 6.2e-07 29.8 1.5 0.0046 17.4 0.0 4.3 4 0 0 4 4 4 2 CBS domain ORC4_C PF14629.6 CEP15514.1 - 1.9e-46 158.2 0.0 3.8e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CEP15514.1 - 1e-16 61.8 0.6 5e-16 59.6 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CEP15514.1 - 5.7e-10 39.7 0.0 1.3e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CEP15514.1 - 5.7e-08 32.2 0.0 9.1e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CEP15514.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEP15514.1 - 7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 CEP15514.1 - 0.00032 20.3 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CEP15514.1 - 0.0018 18.2 0.0 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CEP15514.1 - 0.0028 16.9 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 CEP15514.1 - 0.0032 17.5 0.0 0.014 15.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP15514.1 - 0.0043 17.2 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 CEP15514.1 - 0.0047 16.1 0.1 0.57 9.3 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CEP15514.1 - 0.0063 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CEP15514.1 - 0.0091 16.5 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Sigma54_activat PF00158.26 CEP15514.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 CEP15514.1 - 0.043 13.6 0.4 5.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 CEP15514.1 - 0.045 13.7 0.1 0.14 12.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CEP15514.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP15514.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP15514.1 - 0.092 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase TniB PF05621.11 CEP15514.1 - 0.098 12.1 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein T2SSE PF00437.20 CEP15514.1 - 0.15 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CEP15514.1 - 0.17 12.2 0.0 0.42 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2334 PF10096.9 CEP15515.1 - 0.11 12.1 4.7 0.12 12.0 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DNA_pol_delta_4 PF04081.13 CEP15516.1 - 1.7e-26 93.1 1.2 2.2e-26 92.8 1.2 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Lipase_GDSL PF00657.22 CEP15517.1 - 5e-07 29.9 0.1 6.2e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP15517.1 - 1.9e-06 28.4 0.1 3e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RicinB_lectin_2 PF14200.6 CEP15518.1 - 6.5e-23 81.3 3.1 1.2e-09 38.7 0.0 2.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP15518.1 - 6.4e-16 58.8 2.7 1.7e-09 38.0 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain SoxZ PF08770.11 CEP15518.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Sulphur oxidation protein SoxZ Pep3_Vps18 PF05131.14 CEP15519.1 - 1.2e-48 164.7 0.2 4.2e-48 162.9 0.1 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CEP15519.1 - 9e-13 48.3 14.1 2.9e-10 40.2 4.9 3.8 3 2 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CEP15519.1 - 0.0023 18.4 0.0 0.0069 16.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 CEP15519.1 - 0.093 13.1 3.7 0.29 11.5 3.7 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CEP15519.1 - 0.095 12.7 3.9 0.26 11.3 3.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP15519.1 - 0.14 12.0 7.6 0.069 13.0 5.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEP15519.1 - 0.16 11.6 2.5 0.39 10.4 2.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CEP15519.1 - 0.32 11.3 1.6 0.87 9.9 1.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEP15519.1 - 0.74 9.6 8.0 2.5 7.9 8.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger UPRTase PF14681.6 CEP15520.1 - 2.3e-79 265.6 0.0 2.8e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CEP15520.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Pkinase PF00069.25 CEP15524.1 - 7.1e-49 166.5 1.0 3.2e-48 164.4 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15524.1 - 3.4e-20 72.4 1.0 1.8e-19 70.1 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15524.1 - 1.6e-09 37.6 0.1 4.7e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PRKG1_interact PF15898.5 CEP15524.1 - 0.067 14.1 0.3 0.067 14.1 0.3 5.2 2 2 3 6 6 6 0 cGMP-dependent protein kinase interacting domain APH PF01636.23 CEP15524.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1192 PF06698.11 CEP15524.1 - 0.17 12.0 6.1 2.7 8.1 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF2553 PF10830.8 CEP15524.1 - 0.57 11.0 3.5 3.2 8.6 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) COMP PF11598.8 CEP15524.1 - 1.4 9.5 7.8 1.2 9.7 0.7 3.3 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Pox_A_type_inc PF04508.12 CEP15524.1 - 9.8 6.2 7.2 11 6.1 0.2 4.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 CEP15525.1 - 3.6e-77 259.3 0.0 4e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15525.1 - 1.8e-37 129.0 0.0 2.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15525.1 - 0.00023 20.6 0.1 0.0014 18.1 0.1 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CEP15525.1 - 0.00043 19.3 0.1 0.0051 15.8 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP15525.1 - 0.0011 18.3 0.2 0.002 17.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP15525.1 - 0.036 14.0 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family bZIP_2 PF07716.15 CEP15526.1 - 9.5e-09 35.2 18.5 1.4e-08 34.7 15.6 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 CEP15526.1 - 2e-08 34.2 15.7 5.6e-08 32.8 14.8 2.1 1 1 1 2 2 2 2 bZIP transcription factor KASH_CCD PF14662.6 CEP15526.1 - 0.0017 18.2 9.9 0.0017 18.2 9.9 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CEP15526.1 - 0.0045 17.1 15.6 0.0045 17.1 15.6 1.9 2 1 0 2 2 1 1 TPR/MLP1/MLP2-like protein bZIP_Maf PF03131.17 CEP15526.1 - 0.0053 17.2 12.9 0.016 15.8 12.7 2.0 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF4618 PF15397.6 CEP15526.1 - 0.0098 15.3 5.9 0.014 14.9 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DivIC PF04977.15 CEP15526.1 - 0.034 13.9 4.6 0.034 13.9 4.6 2.8 1 1 2 3 3 3 0 Septum formation initiator DUF4337 PF14235.6 CEP15526.1 - 0.075 13.1 6.4 0.13 12.4 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6_N PF17675.1 CEP15526.1 - 0.092 13.3 12.0 0.19 12.3 12.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region HMMR_N PF15905.5 CEP15526.1 - 0.12 11.8 18.6 0.24 10.8 18.6 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal V_ATPase_I PF01496.19 CEP15526.1 - 0.25 9.2 3.8 0.29 9.0 3.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 CEP15526.1 - 0.54 10.1 12.1 0.92 9.3 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF5320 PF17253.2 CEP15526.1 - 0.98 10.5 5.1 2.6 9.2 4.4 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ADIP PF11559.8 CEP15526.1 - 1.4 9.0 18.0 5.7 7.0 18.0 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Chibby PF14645.6 CEP15526.1 - 2.7 8.4 10.6 7.2 7.1 10.6 1.7 1 1 0 1 1 1 0 Chibby family DUF4407 PF14362.6 CEP15526.1 - 2.8 7.2 11.1 3.7 6.8 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CEP15526.1 - 3.5 6.9 14.2 2.1 7.6 12.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 CEP15526.1 - 9.9 6.7 13.4 6.8 7.2 6.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cyto_heme_lyase PF01265.17 CEP15528.1 - 1.6e-60 205.2 17.5 1.4e-59 202.1 17.5 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Methyltransf_16 PF10294.9 CEP15529.1 - 7.5e-28 97.4 0.0 1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CEP15529.1 - 0.00033 20.5 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP15529.1 - 0.00059 20.5 0.0 0.0018 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP15529.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CEP15529.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Linocin_M18 PF04454.12 CEP15529.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Cons_hypoth95 PF03602.15 CEP15529.1 - 0.16 11.6 0.0 0.51 10.0 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DUF1771 PF08590.10 CEP15530.1 - 4.4e-07 30.2 1.4 1.3e-06 28.7 1.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CEP15530.1 - 4.8e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 CEP15530.1 - 5.7e-07 29.1 0.3 0.0007 19.2 0.2 2.8 2 0 0 2 2 2 2 CUE domain UBA PF00627.31 CEP15530.1 - 0.0046 16.8 0.1 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain MEF2_binding PF09047.10 CEP15530.1 - 0.064 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 MEF2 binding HTH_Tnp_Tc3_2 PF01498.18 CEP15532.1 - 2.7e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Transposase RVT_1 PF00078.27 CEP15533.1 - 2e-16 60.2 0.1 3.6e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CKS PF01111.19 CEP15533.1 - 0.12 12.6 0.0 7.7 6.9 0.0 2.9 2 1 1 3 3 3 0 Cyclin-dependent kinase regulatory subunit DUF3829 PF12889.7 CEP15534.1 - 0.001 18.6 0.2 0.001 18.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3829) Myb_DNA-bind_4 PF13837.6 CEP15534.1 - 0.024 15.0 0.6 0.098 13.1 0.1 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 CEP15535.1 - 2.6e-10 40.2 0.0 6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CEP15535.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein MIP PF00230.20 CEP15536.1 - 2.2e-47 161.7 15.9 2.9e-47 161.3 15.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4574 PF15141.6 CEP15536.1 - 0.1 12.5 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF3493 PF11998.8 CEP15536.1 - 1.2 9.3 8.0 5.5 7.2 0.3 3.0 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 UQ_con PF00179.26 CEP15537.1 - 2.4e-46 156.9 0.0 4.9e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEP15537.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B Ras PF00071.22 CEP15538.1 - 6.7e-48 162.3 0.3 7.7e-48 162.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15538.1 - 1.8e-16 60.4 0.0 2.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15538.1 - 2.5e-10 40.1 0.0 2.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP15538.1 - 1.5e-07 31.1 0.2 4.4e-07 29.6 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CEP15538.1 - 2.7e-06 27.0 0.1 1.2e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEP15538.1 - 2.1e-05 24.5 0.1 0.0043 17.0 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP15538.1 - 4.9e-05 23.4 0.0 7.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEP15538.1 - 0.00064 19.2 0.1 0.00096 18.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 CEP15538.1 - 0.014 15.4 0.0 0.037 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain DUF3978 PF13123.6 CEP15538.1 - 0.039 13.7 0.1 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3978) MeaB PF03308.16 CEP15538.1 - 0.059 12.3 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 CEP15538.1 - 0.068 13.2 0.1 0.16 12.0 0.1 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CEP15538.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Glyco_hydro_cc PF11790.8 CEP15539.1 - 0.086 12.4 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase catalytic core Nop PF01798.18 CEP15539.1 - 0.12 11.8 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin Ribosomal_L7Ae PF01248.26 CEP15540.1 - 7.3e-23 80.1 1.7 1.5e-22 79.2 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 CEP15540.1 - 0.022 14.6 1.0 0.044 13.7 1.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GalP_UDP_tr_C PF02744.17 CEP15540.1 - 0.21 11.3 1.2 9.5 5.9 0.0 2.9 2 1 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain UL42 PF17638.2 CEP15541.1 - 0.2 11.6 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 HCMV UL42 Ribosomal_S10 PF00338.22 CEP15542.1 - 7.6e-29 99.8 0.5 9e-29 99.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2540 PF10802.8 CEP15542.1 - 0.049 13.7 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) SNARE_assoc PF09335.11 CEP15543.1 - 4.2e-17 62.7 6.5 4.2e-17 62.7 6.5 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein Mit_KHE1 PF10173.9 CEP15543.1 - 0.066 13.3 0.7 0.1 12.7 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4013 PF13197.6 CEP15543.1 - 0.076 12.8 0.0 0.076 12.8 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF4013) DUF5345 PF17280.2 CEP15543.1 - 1.6 8.7 6.8 2.4 8.2 0.7 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Amino_oxidase PF01593.24 CEP15544.1 - 3.1e-62 211.4 0.0 1.4e-60 205.9 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP15544.1 - 9.1e-08 32.2 0.1 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEP15544.1 - 2.1e-05 25.0 1.1 0.0034 17.9 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP15544.1 - 2.8e-05 23.9 1.0 0.00011 21.9 1.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP15544.1 - 2.9e-05 23.5 0.3 0.0053 16.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP15544.1 - 4.2e-05 23.1 0.1 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP15544.1 - 0.0053 16.1 0.2 0.19 10.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CEP15544.1 - 0.011 15.1 1.4 0.032 13.5 1.0 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CEP15544.1 - 0.029 13.6 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 CEP15544.1 - 0.03 13.4 1.4 0.06 12.4 1.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CEP15544.1 - 0.053 12.6 1.1 0.077 12.1 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CEP15544.1 - 0.063 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 CEP15544.1 - 0.11 12.4 0.4 1.5 8.8 0.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 CEP15544.1 - 3.5 6.2 4.4 2.6 6.7 0.9 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-MYND PF01753.18 CEP15545.1 - 2.8e-06 27.3 20.1 4.9e-06 26.5 19.1 2.0 1 1 0 1 1 1 1 MYND finger CCDC53 PF10152.9 CEP15545.1 - 0.0062 17.0 10.5 0.16 12.4 5.1 3.0 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex MMR1 PF08505.10 CEP15545.1 - 0.033 14.5 12.6 0.041 14.2 5.0 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Ctr PF04145.15 CEP15545.1 - 0.061 13.9 0.6 0.061 13.9 0.6 2.3 2 1 0 2 2 2 0 Ctr copper transporter family TFB6 PF17110.5 CEP15545.1 - 0.065 13.0 1.5 0.18 11.5 1.5 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH EMC3_TMCO1 PF01956.16 CEP15545.1 - 0.15 11.8 2.6 0.24 11.1 2.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Roughex PF06020.11 CEP15545.1 - 0.22 10.6 8.8 0.034 13.3 4.6 1.7 2 0 0 2 2 2 0 Drosophila roughex protein Ecl1 PF12855.7 CEP15545.1 - 0.33 12.1 20.2 0.48 11.6 8.8 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins CPSF100_C PF13299.6 CEP15545.1 - 0.34 11.1 6.9 0.055 13.7 1.9 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4770 PF15994.5 CEP15545.1 - 0.36 11.0 11.1 2.7 8.2 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) TFIIA PF03153.13 CEP15545.1 - 0.62 10.0 24.3 0.1 12.5 12.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5421 PF17458.2 CEP15545.1 - 0.66 9.3 8.1 1.2 8.5 8.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) TERB2 PF15101.6 CEP15545.1 - 1.6 8.8 10.9 0.54 10.3 7.5 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3299 PF11736.8 CEP15545.1 - 2.3 8.2 7.2 9.1 6.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) Spt20 PF12090.8 CEP15545.1 - 3.8 7.1 25.1 0.18 11.4 16.8 2.1 2 0 0 2 2 2 0 Spt20 family ANAPC4_WD40 PF12894.7 CEP15546.1 - 2.1e-06 27.9 0.1 0.22 11.8 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 CEP15546.1 - 0.012 15.2 5.5 0.4 10.2 0.2 2.7 1 1 1 3 3 3 0 CNH domain WD40 PF00400.32 CEP15546.1 - 0.023 15.6 0.1 3.2 8.8 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat BBS2_N PF14781.6 CEP15546.1 - 0.23 11.4 1.7 15 5.6 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal F-box-like PF12937.7 CEP15547.1 - 2.6e-05 24.0 0.9 7e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 CEP15547.1 - 6.5e-05 22.7 6.1 0.53 10.5 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 CEP15547.1 - 0.00013 22.3 0.0 0.26 11.7 0.0 3.9 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP15547.1 - 0.026 15.0 3.4 74 4.5 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Y_phosphatase3 PF13350.6 CEP15548.1 - 1.5e-52 178.9 0.0 2.2e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 CEP15548.1 - 4.5e-07 29.4 0.0 8.8e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP15548.1 - 2.3e-06 27.5 0.1 1.6e-05 24.7 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP15548.1 - 6.5e-06 26.9 0.0 1.1e-05 26.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase PF00102.27 CEP15548.1 - 0.0093 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_2 PF02230.16 CEP15548.1 - 0.064 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CEP15548.1 - 0.095 12.3 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Toprim PF01751.22 CEP15548.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Toprim domain Y_phosphatase2 PF03162.13 CEP15548.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 CEP15548.1 - 0.16 11.8 0.0 0.55 10.1 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain OrfB_Zn_ribbon PF07282.11 CEP15551.1 - 9.4e-08 31.9 0.4 2.3e-07 30.6 0.4 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RuBisCO_large PF00016.20 CEP15551.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain WD40 PF00400.32 CEP15552.1 - 5.4e-41 137.8 27.0 1.7e-06 28.6 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15552.1 - 4.4e-17 62.1 3.3 0.036 14.4 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP15552.1 - 9.4e-13 47.8 0.5 2.1e-12 46.7 0.5 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CEP15552.1 - 2.6e-10 39.6 7.5 0.085 11.5 0.0 5.6 3 1 3 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP15552.1 - 1.2e-08 34.6 0.3 0.00012 21.5 0.2 3.3 2 1 2 4 4 4 3 WD40-like domain F-box PF00646.33 CEP15552.1 - 1.2e-06 28.3 0.5 2.3e-06 27.3 0.5 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 CEP15552.1 - 0.00097 19.2 1.2 0.031 14.3 0.0 3.7 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 CEP15552.1 - 0.011 14.7 1.3 2.4 7.0 0.2 3.8 1 1 4 5 5 5 0 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 CEP15552.1 - 0.039 13.8 0.0 0.67 9.8 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A CDC4_D PF16856.5 CEP15552.1 - 0.07 13.0 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Ge1_WD40 PF16529.5 CEP15552.1 - 0.08 11.9 0.9 2.4 7.0 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NOA36 PF06524.12 CEP15553.1 - 2.1 7.6 6.4 3.2 7.0 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CEP15553.1 - 2.1 8.3 7.9 3.6 7.6 5.1 2.1 2 1 0 2 2 2 0 RXT2-like, N-terminal CpXC PF14353.6 CEP15555.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 CpXC protein GEP5 PF17053.5 CEP15557.1 - 0.057 13.3 1.4 12 5.7 0.0 2.5 2 1 0 2 2 2 0 Genetic interactor of prohibitin 5 TetR_C_23 PF17931.1 CEP15557.1 - 0.061 13.5 1.7 7.8 6.6 0.3 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1027 PF06265.11 CEP15557.1 - 0.079 13.0 2.2 0.16 12.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) Porphobil_deam PF01379.20 CEP15558.1 - 1.5e-11 44.2 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Pox_A14 PF05767.12 CEP15558.1 - 0.17 12.1 2.3 0.34 11.1 0.0 2.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 TAF PF02969.17 CEP15559.1 - 3.2e-31 107.3 1.4 5.7e-31 106.5 0.2 2.1 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 CEP15559.1 - 1.5e-30 105.4 0.0 4.2e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 CEP15559.1 - 3e-05 24.4 2.1 0.00028 21.2 0.1 2.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CEP15559.1 - 0.00059 19.9 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CEP15559.1 - 0.0088 16.3 0.9 0.045 14.0 0.1 2.7 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.6 CEP15559.1 - 0.017 15.6 0.1 1.4 9.5 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat TFIID_20kDa PF03847.13 CEP15559.1 - 0.052 14.0 0.4 0.6 10.7 0.1 2.7 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Telomere_reg-2 PF10193.9 CEP15559.1 - 0.5 10.8 4.7 8.3 6.9 0.1 3.4 3 1 0 4 4 4 0 Telomere length regulation protein TP6A_N PF04406.14 CEP15560.1 - 4.7e-20 71.3 0.8 1.4e-19 69.9 0.8 1.9 1 0 0 1 1 1 1 Type IIB DNA topoisomerase HTH_28 PF13518.6 CEP15561.1 - 0.0021 18.1 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP15561.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Cas_Cas4 PF01930.17 CEP15561.1 - 0.07 13.2 0.2 0.13 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF83 Ras PF00071.22 CEP15562.1 - 8.7e-48 162.0 0.0 1.1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15562.1 - 4.7e-21 75.2 0.0 1.1e-20 74.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15562.1 - 6.9e-10 38.6 0.0 9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP15562.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Thioredoxin_6 PF13848.6 CEP15562.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Gtr1_RagA PF04670.12 CEP15562.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MitMem_reg PF13012.6 CEP15563.1 - 1.1e-39 135.3 0.4 2.3e-39 134.3 0.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEP15563.1 - 5.5e-32 110.2 0.0 1e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fungal_trans PF04082.18 CEP15564.1 - 2.3e-18 66.2 0.0 4.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP15564.1 - 6.2e-10 39.0 10.5 1.2e-09 38.2 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.26 CEP15565.1 - 3.3e-52 175.9 0.0 3.7e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEP15565.1 - 0.0017 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CEP15565.1 - 0.013 15.8 0.0 0.02 15.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 CEP15565.1 - 0.072 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Thiolase_N PF00108.23 CEP15567.1 - 1.7e-82 276.7 0.0 2.2e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP15567.1 - 2.3e-45 153.2 2.0 3.3e-45 152.7 0.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEP15567.1 - 7e-06 25.8 1.1 1.5e-05 24.7 0.0 2.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain BTB_2 PF02214.22 CEP15568.1 - 0.055 13.8 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Ribosomal_S6e PF01092.19 CEP15569.1 - 5.5e-58 194.4 0.1 5.5e-58 194.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Y_phosphatase2 PF03162.13 CEP15570.1 - 3.3e-55 186.1 0.0 3.6e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEP15570.1 - 0.0003 20.8 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP15570.1 - 0.022 14.3 0.0 0.025 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hormone_4 PF00220.17 CEP15571.1 - 0.23 11.5 2.0 0.48 10.5 2.0 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain EMC3_TMCO1 PF01956.16 CEP15573.1 - 8e-53 178.7 0.2 1.4e-52 177.9 0.2 1.4 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Asp PF00026.23 CEP15574.1 - 7.5e-86 288.4 0.0 8.9e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP15574.1 - 7.8e-14 52.3 0.2 7.6e-08 32.8 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CEP15574.1 - 0.12 13.0 0.1 15 6.3 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease Ldh_1_N PF00056.23 CEP15575.1 - 6.2e-16 58.8 0.0 1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CEP15575.1 - 0.0024 17.8 0.2 0.0051 16.7 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CEP15575.1 - 0.0039 17.1 0.0 0.01 15.8 0.0 1.6 1 1 1 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.21 CEP15575.1 - 0.0065 15.8 0.1 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 ThiF family Pyr_redox PF00070.27 CEP15575.1 - 0.033 14.7 0.1 0.43 11.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CEP15575.1 - 0.044 13.4 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 CEP15575.1 - 0.05 13.9 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP15575.1 - 0.06 12.9 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase PDEase_I PF00233.19 CEP15577.1 - 4.4e-70 236.1 2.7 5.9e-70 235.7 2.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CEP15577.1 - 9.4e-07 29.1 1.0 4.2e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 HD domain HD_2 PF12917.7 CEP15577.1 - 0.081 12.7 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Malic_M PF03949.15 CEP15578.1 - 1.8e-81 273.2 0.1 2.5e-81 272.7 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEP15578.1 - 7.8e-59 198.5 0.0 2.3e-58 197.0 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF2408 PF10303.9 CEP15579.1 - 2.2e-36 125.4 0.1 3.6e-24 85.8 0.0 4.3 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Polysacc_deac_1 PF01522.21 CEP15580.1 - 7.2e-27 93.7 0.1 1.3e-26 92.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Anillin PF08174.11 CEP15581.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Cell division protein anillin ERCC3_RAD25_C PF16203.5 CEP15582.1 - 3.1e-125 416.3 0.6 5.6e-125 415.5 0.6 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CEP15582.1 - 5.6e-39 133.2 0.0 2e-38 131.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP15582.1 - 4.4e-16 59.3 0.0 9.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP15582.1 - 5e-11 42.9 0.1 2.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CEP15582.1 - 3.5e-09 35.9 0.0 4.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CEP15582.1 - 7.7e-05 22.5 0.3 0.00037 20.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase MOZ_SAS PF01853.18 CEP15584.1 - 4.3e-84 280.6 0.2 6.5e-84 280.0 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CEP15584.1 - 2.2e-22 78.4 3.7 5.8e-22 77.1 3.7 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CEP15584.1 - 2.4e-20 72.2 0.0 5.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CEP15584.1 - 0.0064 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP15584.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 CEP15584.1 - 0.05 13.6 0.5 0.12 12.4 0.5 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 CEP15584.1 - 0.073 13.0 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 HTH domain Phage_portal PF04860.12 CEP15584.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 1 0 1 1 1 0 Phage portal protein Iwr1 PF08574.10 CEP15584.1 - 0.12 13.4 4.5 0.31 12.1 3.5 2.2 2 0 0 2 2 2 0 Transcription factor Iwr1 Pox_Ag35 PF03286.14 CEP15584.1 - 3.5 7.4 8.3 0.83 9.4 4.9 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein WD40 PF00400.32 CEP15586.1 - 4.7e-49 163.3 14.9 2.1e-07 31.5 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15586.1 - 3e-15 56.3 2.6 0.0019 18.5 0.0 6.3 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP15586.1 - 3.4e-06 27.1 0.5 0.00051 20.0 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEP15586.1 - 0.00018 20.3 3.5 0.025 13.2 0.2 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 LisH_TPL PF17814.1 CEP15586.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40_like PF17005.5 CEP15586.1 - 0.0022 17.4 0.1 1.8 7.8 0.0 3.2 2 1 0 3 3 3 2 WD40-like domain HTH_6 PF01418.17 CEP15586.1 - 0.57 10.2 2.0 1.3 9.0 2.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family FlxA PF14282.6 CEP15587.1 - 0.018 15.0 6.3 0.046 13.7 6.3 1.6 1 0 0 1 1 1 0 FlxA-like protein F-box-like PF12937.7 CEP15589.1 - 4.9e-07 29.6 0.7 1e-06 28.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP15589.1 - 0.00055 19.7 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP15590.1 - 0.0014 18.5 3.5 0.034 14.0 2.0 3.1 2 1 0 2 2 2 1 F-box-like DNA_pol3_a_NI PF14480.6 CEP15590.1 - 0.13 12.3 0.3 0.53 10.3 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I RNA_polI_A34 PF08208.11 CEP15591.1 - 6.4e-24 85.2 12.6 8.9e-24 84.7 12.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 CEP15591.1 - 0.21 10.3 2.2 0.2 10.4 2.2 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 CEP15591.1 - 1.3 9.4 8.3 0.38 11.2 4.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 ubiquitin PF00240.23 CEP15592.1 - 1.9e-21 75.6 0.1 3.4e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP15592.1 - 1.3e-09 37.7 0.2 2.3e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CEP15592.1 - 2.8e-06 27.1 0.3 2.8e-06 27.1 0.3 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TBK1_ULD PF18396.1 CEP15592.1 - 0.00038 20.3 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CEP15592.1 - 0.00055 20.5 0.2 0.002 18.6 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CEP15592.1 - 0.0024 17.9 0.6 0.036 14.1 0.5 2.2 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CEP15592.1 - 0.0072 16.4 0.1 0.0072 16.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 CEP15592.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 CEP15592.1 - 0.1 12.6 15.0 1.4 9.0 4.5 3.9 3 1 1 4 4 4 0 STI1 domain Ubiquitin_5 PF18037.1 CEP15592.1 - 0.12 12.8 0.2 0.22 11.9 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 CEP15592.1 - 0.58 10.1 4.4 7.5 6.5 1.5 3.2 2 1 1 3 3 3 0 Spore germination GerD central core domain DUF2362 PF10154.9 CEP15593.1 - 2.5e-72 244.5 30.7 4.2e-34 118.3 0.0 4.3 1 1 1 3 3 3 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 CEP15593.1 - 3.8e-05 23.5 0.3 7.9e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Cyclin PF08613.11 CEP15595.1 - 2.6e-14 53.9 0.2 4.9e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP15595.1 - 2e-08 34.0 0.5 3.3e-08 33.3 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Biotin_lipoyl PF00364.22 CEP15596.1 - 8.9e-19 67.1 0.1 2.4e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CEP15596.1 - 1.6e-07 31.5 0.4 4.4e-07 30.1 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CEP15596.1 - 0.005 16.6 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like 2-oxoacid_dh PF00198.23 CEP15596.1 - 0.015 14.8 0.0 0.073 12.5 0.0 2.0 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Polysacc_deac_1 PF01522.21 CEP15597.1 - 2.4e-35 121.1 0.0 5.3e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP15597.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 zf-met2 PF12907.7 CEP15598.1 - 4.1e-16 58.8 4.8 5.9e-16 58.3 4.8 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CEP15598.1 - 0.37 11.7 7.2 6.2 7.8 2.0 2.2 2 0 0 2 2 2 0 4F5 protein family Erg28 PF03694.13 CEP15599.1 - 1.4e-40 138.1 2.9 2.1e-39 134.3 1.3 2.7 2 0 0 2 2 2 1 Erg28 like protein DUF3176 PF11374.8 CEP15599.1 - 8.9e-11 41.9 2.2 9.6e-11 41.8 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Pox_M2 PF04887.12 CEP15599.1 - 0.11 12.0 0.1 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Poxvirus M2 protein TRAPPC9-Trs120 PF08626.11 CEP15600.1 - 0 1033.1 0.0 0 1020.0 0.0 2.0 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CEP15600.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP15600.1 - 0.04 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP15600.1 - 0.058 13.5 0.1 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_rhamnosid_C PF17390.2 CEP15600.1 - 0.083 12.7 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain TPR_14 PF13428.6 CEP15600.1 - 0.093 13.6 0.3 5.4 8.1 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Per1 PF04080.13 CEP15601.1 - 1.9e-81 273.6 16.1 2.2e-81 273.4 16.1 1.0 1 0 0 1 1 1 1 Per1-like family Adipogenin PF15202.6 CEP15601.1 - 0.56 10.3 4.2 6.5 6.8 0.0 2.8 2 1 1 3 3 3 0 Adipogenin Ferritin PF00210.24 CEP15602.1 - 5e-38 130.2 2.6 1e-37 129.2 2.6 1.6 1 0 0 1 1 1 1 Ferritin-like domain Aminotran_1_2 PF00155.21 CEP15602.1 - 8.6e-38 130.4 0.0 1.5e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Rubrerythrin PF02915.17 CEP15602.1 - 3.7e-07 30.6 0.2 1.1e-06 29.1 0.2 1.8 1 0 0 1 1 1 1 Rubrerythrin LppA PF16708.5 CEP15602.1 - 0.017 15.0 0.3 0.036 14.0 0.3 1.5 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium RVT_1 PF00078.27 CEP15603.1 - 7.7e-36 123.7 0.0 1.4e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP15603.1 - 4.7e-08 33.6 0.6 4.7e-08 33.6 0.6 2.7 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 CEP15603.1 - 6.9e-06 25.9 0.4 6.9e-06 25.9 0.4 2.4 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP15603.1 - 0.00027 20.9 16.6 0.0037 17.3 3.0 2.9 2 0 0 2 2 2 2 Zinc knuckle Anti-TRAP PF15777.5 CEP15603.1 - 0.52 10.3 1.8 1.2 9.1 1.8 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cwf_Cwc_15 PF04889.12 CEP15603.1 - 0.86 9.3 8.2 1.6 8.4 8.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DnaJ_CXXCXGXG PF00684.19 CEP15603.1 - 4.2 7.8 6.2 17 5.9 5.7 2.3 2 0 0 2 2 2 0 DnaJ central domain Ribosomal_S25 PF03297.15 CEP15604.1 - 3.5e-37 126.7 1.8 4.2e-37 126.4 1.8 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 CEP15604.1 - 0.02 14.4 0.4 0.031 13.8 0.4 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CEP15604.1 - 0.024 14.5 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 MarR family LRR_4 PF12799.7 CEP15605.1 - 6.2e-13 48.7 12.6 0.0001 22.6 3.1 5.4 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP15605.1 - 8.6e-09 35.0 23.4 8.5e-08 31.8 7.5 4.4 4 1 1 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 CEP15605.1 - 2.1e-06 27.4 0.1 0.43 10.1 0.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CEP15605.1 - 0.003 17.9 7.0 17 6.4 0.1 6.4 6 1 0 6 6 6 1 Leucine Rich Repeat DUF2175 PF09943.9 CEP15605.1 - 4.2 7.7 4.8 4.8 7.5 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Amidohydro_1 PF01979.20 CEP15606.1 - 1.4e-69 235.1 1.0 2.2e-69 234.4 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 CEP15606.1 - 2.1e-53 179.8 1.2 4.1e-53 178.8 1.2 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 CEP15606.1 - 1.5e-41 140.7 0.1 5.4e-41 138.9 0.1 2.0 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 CEP15606.1 - 7.7e-39 131.7 0.0 1.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_3 PF07969.11 CEP15606.1 - 1.1e-05 25.1 0.1 8.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family cobW PF02492.19 CEP15607.1 - 3.1e-33 114.9 0.0 3.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CEP15607.1 - 0.0015 17.5 0.4 1.5 7.7 0.0 2.5 2 1 1 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CEP15607.1 - 0.0022 18.1 0.0 0.036 14.1 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 CEP15607.1 - 0.0083 16.1 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 CEP15607.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CEP15607.1 - 0.027 15.0 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEP15607.1 - 0.035 14.0 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CEP15607.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 CEP15607.1 - 0.063 13.7 0.0 0.083 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.13 CEP15607.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Pox_A32 PF04665.12 CEP15607.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 CEP15607.1 - 0.14 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Lactonase PF10282.9 CEP15608.1 - 1.8e-107 359.6 0.3 2.1e-107 359.4 0.3 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 CEP15608.1 - 0.13 11.4 0.2 0.29 10.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) SWIB PF02201.18 CEP15609.1 - 2.6e-25 88.1 0.5 8.9e-25 86.4 0.2 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain UDPGT PF00201.18 CEP15610.1 - 7.1e-29 101.0 0.0 1e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEP15610.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ACT_7 PF13840.6 CEP15611.1 - 1.5e-30 104.8 0.0 5.7e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 CEP15611.1 - 9.5e-05 22.1 0.6 0.0037 17.1 0.2 2.4 2 0 0 2 2 2 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Ank_2 PF12796.7 CEP15612.1 - 8.9e-10 39.0 0.0 3e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEP15612.1 - 9.1e-09 35.4 3.0 0.0044 17.4 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat zf-met PF12874.7 CEP15612.1 - 1.1e-08 35.2 8.9 0.0062 16.9 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Ank_4 PF13637.6 CEP15612.1 - 1.7e-07 31.7 0.0 1.4e-05 25.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP15612.1 - 4.2e-07 30.1 0.3 0.00033 20.9 0.2 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP15612.1 - 8.1e-07 28.9 0.5 0.33 11.6 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2_2 PF12756.7 CEP15612.1 - 9.2e-06 25.9 3.5 0.0034 17.7 0.6 3.2 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CEP15612.1 - 0.00035 20.8 15.9 0.019 15.2 1.8 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP15612.1 - 0.0023 18.6 27.2 0.055 14.3 3.9 4.3 4 0 0 4 4 3 2 C2H2-type zinc finger HAP1_N PF04849.13 CEP15612.1 - 0.0066 15.7 14.2 0.044 13.0 1.6 2.2 1 1 1 2 2 2 2 HAP1 N-terminal conserved region COG7 PF10191.9 CEP15612.1 - 0.025 12.8 6.8 0.027 12.7 2.2 2.1 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) CENP-F_leu_zip PF10473.9 CEP15612.1 - 0.076 13.0 9.8 1.4 9.0 4.4 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf_C2H2_ZHX PF18387.1 CEP15612.1 - 0.53 10.0 6.9 9 6.0 0.3 3.4 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Mucin PF01456.17 CEP15612.1 - 0.68 9.9 17.1 1.4 8.9 17.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Spc7 PF08317.11 CEP15612.1 - 0.74 8.6 12.9 0.02 13.8 3.3 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Latarcin PF10279.9 CEP15612.1 - 1.3 9.4 4.3 3.6 8.1 2.8 2.4 2 1 0 2 2 1 0 Latarcin precursor zf-C2H2 PF00096.26 CEP15612.1 - 2.7 8.6 23.9 1.4 9.6 4.3 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type TMPIT PF07851.13 CEP15612.1 - 3.2 6.9 11.8 2.2 7.5 6.4 2.4 1 1 1 2 2 2 0 TMPIT-like protein PLDc_N PF13396.6 CEP15613.1 - 1.3e-05 25.0 2.4 2.1e-05 24.4 2.4 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal RRM_1 PF00076.22 CEP15614.1 - 3.8e-32 109.9 0.0 5.5e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP15614.1 - 0.0013 18.7 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CEP15614.1 - 0.0025 17.9 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif SR-25 PF10500.9 CEP15614.1 - 3.4 7.2 64.3 0.16 11.6 32.9 2.7 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Raftlin PF15250.6 CEP15614.1 - 4.1 6.0 13.9 6.6 5.4 13.9 1.4 1 0 0 1 1 1 0 Raftlin Mito_carr PF00153.27 CEP15615.1 - 6e-71 234.4 0.9 1.8e-23 82.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CEP15616.1 - 5.3e-66 222.7 0.0 1.2e-65 221.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15616.1 - 6.5e-36 123.9 0.9 1.1e-35 123.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.16 CEP15616.1 - 4.8e-17 61.8 3.8 2.6e-11 43.5 0.3 3.5 4 0 0 4 4 4 2 Hr1 repeat C1_1 PF00130.22 CEP15616.1 - 5.8e-17 61.3 27.1 2e-10 40.4 11.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CEP15616.1 - 8.3e-10 39.2 3.1 1.8e-09 38.1 1.2 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CEP15616.1 - 0.0058 15.6 0.7 0.011 14.7 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain zf-tcix PF14952.6 CEP15616.1 - 0.0097 15.5 3.2 0.0097 15.5 3.2 2.3 3 0 0 3 3 3 1 Putative treble-clef, zinc-finger, Zn-binding C1_2 PF03107.16 CEP15616.1 - 0.28 11.5 20.9 0.76 10.1 9.7 2.7 2 0 0 2 2 2 0 C1 domain Pkinase_fungal PF17667.1 CEP15616.1 - 0.39 9.4 2.6 0.41 9.4 0.1 2.2 2 1 0 2 2 2 0 Fungal protein kinase FHA PF00498.26 CEP15618.1 - 8.2e-06 26.1 0.2 1.9e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 CEP15618.1 - 0.00031 20.9 0.0 0.00086 19.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain GcrA PF07750.11 CEP15618.1 - 0.083 13.3 1.2 0.24 11.8 0.0 2.4 2 1 1 3 3 3 0 GcrA cell cycle regulator CaM_binding PF07839.11 CEP15618.1 - 0.32 11.7 5.6 1.8 9.3 5.6 2.3 1 1 0 1 1 1 0 Plant calmodulin-binding domain AROS PF15684.5 CEP15618.1 - 1.8 9.2 9.2 5.8 7.5 0.3 2.8 3 0 0 3 3 3 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 LAG1-DNAbind PF09271.11 CEP15619.1 - 2.5e-23 83.4 2.1 2.5e-23 83.4 2.1 3.6 2 2 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 CEP15619.1 - 1e-20 74.5 0.0 5.9e-09 36.3 0.0 2.8 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain Exo_endo_phos PF03372.23 CEP15620.1 - 1.3e-06 28.1 0.0 4.4e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP15620.1 - 6.1e-05 22.9 2.1 0.00011 22.1 0.0 2.5 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase CC190 PF15768.5 CEP15620.1 - 0.6 10.1 10.7 0.98 9.4 10.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Pkinase PF00069.25 CEP15623.1 - 1.4e-47 162.3 0.0 2.4e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15623.1 - 3.9e-23 82.1 0.0 1.6e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15623.1 - 0.0017 17.8 0.0 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Herpes_UL36 PF03586.13 CEP15623.1 - 0.1 11.9 0.8 0.2 11.0 0.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DivIC PF04977.15 CEP15623.1 - 7.9 6.3 9.9 0.37 10.6 2.7 2.4 3 0 0 3 3 3 0 Septum formation initiator RabGAP-TBC PF00566.18 CEP15624.1 - 2.4e-54 184.3 0.1 2.4e-54 184.3 0.1 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain bZIP_1 PF00170.21 CEP15624.1 - 0.32 11.1 14.8 1.4 9.1 1.6 3.6 3 0 0 3 3 3 0 bZIP transcription factor APG17 PF04108.12 CEP15625.1 - 0.0086 15.2 2.3 0.011 14.9 2.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Rx_N PF18052.1 CEP15625.1 - 0.011 16.0 0.2 0.13 12.6 0.0 2.2 2 1 0 2 2 2 0 Rx N-terminal domain RPM2 PF08579.11 CEP15625.1 - 0.39 11.1 3.2 14 6.1 0.5 2.7 1 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Mucin PF01456.17 CEP15626.1 - 0.99 9.4 34.9 1.9 8.5 16.7 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein His_biosynth PF00977.21 CEP15627.1 - 1.7e-48 165.1 0.0 9.9e-48 162.6 0.0 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CEP15627.1 - 1.9e-22 80.0 0.0 3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CEP15627.1 - 4.3e-09 36.3 0.0 1.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CEP15627.1 - 5.7e-09 36.1 0.0 4e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 CEP15627.1 - 0.013 15.3 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 NMO PF03060.15 CEP15627.1 - 0.03 13.7 0.2 0.071 12.5 0.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase BPL_N PF09825.9 CEP15627.1 - 0.096 11.7 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Dus PF01207.17 CEP15627.1 - 0.24 10.5 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Mcp5_PH PF12814.7 CEP15628.1 - 3.7e-30 104.5 1.1 1.4e-29 102.7 0.0 2.6 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1363 PF07101.11 CEP15628.1 - 0.021 15.1 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) Pkinase PF00069.25 CEP15630.1 - 4.9e-61 206.4 0.0 4.9e-61 206.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15630.1 - 2e-40 138.7 0.6 5.9e-40 137.2 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Ras PF00071.22 CEP15631.1 - 4e-58 195.6 0.3 5.3e-58 195.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15631.1 - 4.5e-37 126.9 0.1 9.7e-37 125.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15631.1 - 2.4e-16 59.7 0.1 3e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEP15631.1 - 3.5e-07 29.8 0.2 5.1e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CEP15631.1 - 1.9e-06 27.6 0.1 1.1e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP15631.1 - 2.5e-05 24.3 0.1 6.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP15631.1 - 3.8e-05 23.7 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CEP15631.1 - 5.9e-05 22.5 0.4 7.8e-05 22.1 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CEP15631.1 - 0.00063 19.3 0.1 0.053 13.0 0.1 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CEP15631.1 - 0.0042 16.9 0.2 0.016 15.0 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CEP15631.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CEP15631.1 - 0.094 12.1 0.1 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein SurE PF01975.17 CEP15632.1 - 1.9e-49 168.1 0.0 2.3e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE bZIP_1 PF00170.21 CEP15633.1 - 1.5e-07 31.4 10.4 9.4e-07 28.8 10.4 2.3 1 1 0 1 1 1 1 bZIP transcription factor DUF150_C PF17384.2 CEP15633.1 - 0.039 14.1 1.9 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 RimP C-terminal SH3 domain bZIP_2 PF07716.15 CEP15633.1 - 1.8 8.7 17.8 0.047 13.8 5.5 3.1 3 0 0 3 3 3 0 Basic region leucine zipper UNC-93 PF05978.16 CEP15634.1 - 6.2e-12 45.5 10.1 1e-11 44.8 7.1 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CEP15634.1 - 3.7e-11 42.6 41.5 3.7e-11 42.6 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily XLF PF09302.11 CEP15635.1 - 2.3e-10 40.9 0.8 4.3e-10 40.1 0.5 1.6 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component QRPTase_C PF01729.19 CEP15636.1 - 1.7e-57 193.9 0.1 2e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CEP15636.1 - 1.1e-20 73.4 0.0 2.4e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain VEFS-Box PF09733.9 CEP15636.1 - 0.017 14.9 0.1 0.094 12.5 0.0 1.9 2 0 0 2 2 2 0 VEFS-Box of polycomb protein SBD_N PF07005.11 CEP15636.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Sugar-binding N-terminal domain RBD-FIP PF09457.10 CEP15637.1 - 0.0096 15.8 0.9 0.048 13.6 0.9 2.3 1 0 0 1 1 1 1 FIP domain CK2S PF15011.6 CEP15637.1 - 0.071 13.0 14.5 1.3 8.9 4.4 3.4 3 0 0 3 3 3 0 Casein Kinase 2 substrate APC_N_CC PF16689.5 CEP15637.1 - 1.2 9.2 11.3 1.5 8.9 3.5 2.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF641 PF04859.12 CEP15637.1 - 1.4 9.2 16.8 3 8.2 6.1 3.2 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) CCDC92 PF14916.6 CEP15637.1 - 2.2 8.1 14.2 1.2 9.0 0.2 3.5 3 0 0 3 3 3 0 Coiled-coil domain of unknown function YqzH PF14164.6 CEP15637.1 - 2.7 8.1 5.7 1.6 8.8 0.6 3.0 2 1 0 3 3 3 0 YqzH-like protein Lectin_C PF00059.21 CEP15638.1 - 0.012 16.3 2.8 0.022 15.5 1.8 2.0 2 0 0 2 2 2 0 Lectin C-type domain PEPCK_ATP PF01293.20 CEP15639.1 - 1e-224 746.5 0.0 1.2e-224 746.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 CEP15639.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Chitin_synth_1 PF01644.17 CEP15640.1 - 6.9e-74 247.3 0.1 1e-73 246.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEP15640.1 - 8e-32 109.0 0.1 2.1e-31 107.7 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CEP15640.1 - 5.7e-23 81.3 2.6 4.9e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP15640.1 - 0.00011 22.2 6.6 0.00011 22.2 6.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DDE_3 PF13358.6 CEP15641.1 - 4.9e-23 81.5 0.1 1.4e-20 73.5 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP15641.1 - 0.00097 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain rve PF00665.26 CEP15641.1 - 0.014 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF896 PF05979.12 CEP15641.1 - 0.023 14.6 0.1 0.057 13.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF3800 PF12686.7 CEP15641.1 - 0.059 14.0 0.0 0.081 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) OrfB_Zn_ribbon PF07282.11 CEP15642.1 - 3.7e-11 42.8 1.4 3.7e-11 42.8 1.4 2.2 2 0 0 2 2 2 1 Putative transposase DNA-binding domain RuvX PF03652.15 CEP15642.1 - 0.038 14.4 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction resolvase DUF384 PF04064.13 CEP15642.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) TAL_FSA PF00923.19 CEP15643.1 - 5.4e-100 334.4 0.1 6.2e-100 334.3 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase 4HBT_3 PF13622.6 CEP15644.1 - 4.6e-63 213.8 0.1 5.5e-63 213.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CEP15644.1 - 2e-35 121.5 0.0 4e-27 94.7 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Peptidase_M16_C PF05193.21 CEP15645.1 - 9.7e-37 126.7 0.1 2.2e-36 125.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CEP15645.1 - 7.9e-29 100.6 0.8 2.7e-28 98.8 0.4 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) UQ_con PF00179.26 CEP15646.1 - 1.9e-38 131.3 0.1 2.7e-38 130.8 0.1 1.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Velvet PF11754.8 CEP15647.1 - 4.3e-38 131.7 3.4 1.3e-26 94.0 0.7 3.4 2 2 1 3 3 3 2 Velvet factor BAG PF02179.16 CEP15648.1 - 3.5e-10 40.2 0.2 3.5e-10 40.2 0.2 3.3 3 2 0 3 3 3 1 BAG domain CPP1-like PF11833.8 CEP15648.1 - 0.75 9.4 10.8 1.7 8.3 10.8 1.6 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tubulin PF00091.25 CEP15650.1 - 1.1e-63 215.0 0.0 1.8e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP15650.1 - 4.3e-41 140.0 0.0 6.7e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEP15650.1 - 0.037 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 CEP15650.1 - 0.076 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like SR-25 PF10500.9 CEP15653.1 - 0.0027 17.4 11.0 0.0027 17.4 11.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CEP15653.1 - 0.0043 17.7 10.5 0.0054 17.4 10.5 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein TLP-20 PF06088.11 CEP15653.1 - 0.078 12.9 1.2 0.089 12.7 1.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF755 PF05501.11 CEP15653.1 - 0.25 11.6 13.4 0.29 11.4 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3654 PF12376.8 CEP15654.1 - 0.017 15.3 2.3 0.036 14.2 1.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3654) Lyase_1 PF00206.20 CEP15655.1 - 3.8e-22 79.1 0.0 5.7e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CEP15655.1 - 3.6e-16 59.4 0.0 1.2e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 CEP15655.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) ExoD PF06055.12 CEP15655.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Sugar_tr PF00083.24 CEP15656.1 - 7.8e-55 186.5 20.4 9.1e-55 186.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP15656.1 - 1.1e-24 87.0 39.1 1.4e-23 83.4 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2198 PF09964.9 CEP15656.1 - 0.7 10.0 0.1 0.7 10.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) ArAE_1 PF06081.11 CEP15656.1 - 6 7.0 10.9 0.53 10.4 3.0 2.8 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 FliC_SP PF12613.8 CEP15657.1 - 0.13 12.8 2.3 0.18 12.4 2.3 1.2 1 0 0 1 1 1 0 Flagellin structural protein zf-C2H2 PF00096.26 CEP15658.1 - 2.3e-08 34.0 9.6 8.9e-05 22.7 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP15658.1 - 4.4e-05 23.7 1.7 4.4e-05 23.7 1.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP15658.1 - 0.0045 17.7 7.4 0.74 10.8 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP15658.1 - 0.024 15.2 1.2 0.67 10.6 0.1 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CEP15658.1 - 0.12 12.5 1.4 1.2 9.2 0.1 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 CEP15658.1 - 0.18 12.2 6.4 0.17 12.2 3.6 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CEP15658.1 - 2 8.5 4.5 0.53 10.3 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger IBR PF01485.21 CEP15659.1 - 0.0088 16.3 1.4 0.063 13.5 0.1 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain DUSP PF06337.12 CEP15659.1 - 0.012 16.2 0.0 0.036 14.7 0.0 1.9 1 1 0 1 1 1 0 DUSP domain C1_2 PF03107.16 CEP15659.1 - 0.23 11.8 0.1 0.23 11.8 0.1 2.6 2 0 0 2 2 2 0 C1 domain GTP_EFTU PF00009.27 CEP15660.1 - 1.2e-57 194.6 0.0 2.3e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain COBRA1 PF06209.13 CEP15660.1 - 3.3e-44 151.5 6.6 6.8e-44 150.5 6.6 1.5 1 1 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) EFG_C PF00679.24 CEP15660.1 - 7e-15 54.8 0.0 2.3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CEP15660.1 - 4.2e-09 36.4 0.1 9.6e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CEP15660.1 - 2e-06 28.1 0.0 5.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CEP15660.1 - 0.014 15.2 0.0 0.047 13.5 0.0 2.0 1 0 0 1 1 1 0 Elongation factor G, domain IV Nodulin_late PF07127.11 CEP15661.1 - 0.0014 18.9 0.7 0.002 18.4 0.7 1.3 1 0 0 1 1 1 1 Late nodulin protein Dickkopf_N PF04706.12 CEP15661.1 - 0.0045 17.4 1.7 0.006 17.0 1.7 1.1 1 0 0 1 1 1 1 Dickkopf N-terminal cysteine-rich region CarbpepA_inh PF02977.15 CEP15661.1 - 0.011 15.5 1.9 0.02 14.7 1.9 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor PP2C PF00481.21 CEP15662.1 - 4.4e-13 49.5 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 CEP15662.1 - 4.4e-13 49.6 0.0 8e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CEP15662.1 - 6.7e-07 29.2 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L19e PF01280.20 CEP15663.1 - 3e-61 205.7 9.5 3e-61 205.7 9.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e Alpha_TIF PF02232.15 CEP15663.1 - 0.042 13.0 0.8 0.053 12.6 0.8 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) LRR_8 PF13855.6 CEP15664.1 - 5.7e-07 29.2 1.4 3e-06 26.9 1.9 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CEP15664.1 - 5.1e-06 26.7 11.8 0.00031 21.1 1.2 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) zf-FCS PF06467.14 CEP15664.1 - 0.095 12.7 3.0 0.37 10.8 3.0 2.0 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Lipase_GDSL PF00657.22 CEP15665.1 - 6.9e-10 39.2 0.4 9.6e-10 38.8 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP15665.1 - 4.9e-08 33.6 0.1 6.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MAPEG PF01124.18 CEP15667.1 - 3.7e-24 85.1 0.3 4.2e-24 84.9 0.3 1.0 1 0 0 1 1 1 1 MAPEG family Sulfate_transp PF00916.20 CEP15668.1 - 5.3e-95 318.4 16.8 7.6e-95 317.9 16.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP15668.1 - 5.9e-20 71.1 0.1 1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP15668.1 - 5.4e-05 23.6 5.0 5.4e-05 23.6 5.0 3.4 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily DUF2254 PF10011.9 CEP15668.1 - 0.00043 19.2 1.1 0.00043 19.2 1.1 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) SHMT PF00464.19 CEP15669.1 - 8.3e-173 574.6 0.0 1e-172 574.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CEP15669.1 - 1.4e-05 24.6 0.0 5.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CEP15669.1 - 5.1e-05 22.6 0.0 0.00014 21.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 CEP15669.1 - 0.033 14.4 0.1 0.077 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) WD40 PF00400.32 CEP15670.1 - 1.8e-17 63.3 13.5 0.014 16.3 0.5 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15670.1 - 5.7e-07 29.7 2.3 0.22 11.8 0.1 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP15670.1 - 0.00029 20.8 0.1 0.32 10.9 0.0 3.8 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Myb_DNA-binding PF00249.31 CEP15670.1 - 0.0091 16.2 0.0 0.032 14.4 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase_Tyr PF07714.17 CEP15671.1 - 1.4e-21 76.9 0.0 2.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CEP15671.1 - 3e-21 76.0 0.0 6.8e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 CEP15671.1 - 0.0017 18.0 0.4 0.0029 17.2 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CEP15671.1 - 0.0058 15.6 0.2 0.026 13.5 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APG5 PF04106.12 CEP15672.1 - 2.2e-55 187.7 0.3 4.3e-55 186.8 0.3 1.5 1 0 0 1 1 1 1 Autophagy protein Apg5 Homeobox_KN PF05920.11 CEP15673.1 - 6.5e-19 67.5 0.3 1.7e-18 66.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CEP15673.1 - 9.4e-09 35.0 0.3 2.1e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 Homeodomain RhoGAP PF00620.27 CEP15674.1 - 5.5e-08 32.8 0.1 2.1e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C34 PF05413.11 CEP15674.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Snapin_Pallidin PF14712.6 CEP15674.1 - 0.033 14.6 0.8 0.073 13.5 0.8 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DEAD PF00270.29 CEP15675.1 - 6.4e-34 117.2 0.2 4.2e-33 114.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP15675.1 - 7e-28 97.2 0.1 3.9e-27 94.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HAD_2 PF13419.6 CEP15675.1 - 1.2e-17 64.6 0.2 5.9e-17 62.3 0.2 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP15675.1 - 1.5e-14 54.8 0.0 3.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ResIII PF04851.15 CEP15675.1 - 6e-08 32.9 0.0 3.4e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Hydrolase_like PF13242.6 CEP15675.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CEP15675.1 - 0.0073 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_30 PF13604.6 CEP15675.1 - 0.056 13.2 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.20 CEP15677.1 - 6.8e-135 449.5 0.0 7.6e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEP15677.1 - 1.9e-10 40.5 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEP15677.1 - 4.3e-10 39.1 0.1 6.3e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEP15677.1 - 1.4e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 CEP15677.1 - 0.00037 19.1 0.0 0.00052 18.6 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 CEP15677.1 - 0.0059 15.9 0.0 0.022 14.0 0.0 1.8 1 1 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.16 CEP15677.1 - 0.02 13.7 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 CEP15677.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain M20_dimer PF07687.14 CEP15677.1 - 0.1 12.5 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase dimerisation domain SUIM_assoc PF16619.5 CEP15678.1 - 7.9 6.6 10.8 0.34 11.0 1.3 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 GATA PF00320.27 CEP15679.1 - 4.5e-16 58.2 8.1 9.2e-16 57.2 8.1 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 CEP15679.1 - 2.3e-13 50.2 0.3 1.2e-12 47.9 0.0 2.3 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 CEP15679.1 - 3.4e-10 39.9 1.0 2.4e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CEP15679.1 - 8.1e-07 29.2 0.0 3e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 PAS domain PAS_11 PF14598.6 CEP15679.1 - 8.2e-06 25.9 3.4 1.3e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 CEP15679.1 - 0.0019 18.3 0.2 0.0063 16.6 0.1 1.9 2 0 0 2 2 2 1 Zinc ribbon domain TFIIA PF03153.13 CEP15679.1 - 0.0051 16.9 18.5 0.0051 16.9 18.5 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PAS_4 PF08448.10 CEP15679.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold NAD_binding_6 PF08030.12 CEP15679.1 - 1.4 9.0 10.2 3.9 7.6 0.4 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Cyclin PF08613.11 CEP15680.1 - 8.2e-09 36.0 1.9 1.1e-08 35.6 0.1 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP15680.1 - 3.6e-08 33.2 0.1 5.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Csm1 PF12539.8 CEP15681.1 - 1.7e-17 63.8 0.0 4.9e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 CEP15681.1 - 3.9e-05 23.8 5.1 3.9e-05 23.8 5.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5094) FlaC_arch PF05377.11 CEP15681.1 - 0.004 17.5 1.1 0.012 16.0 0.4 2.2 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) FliD_N PF02465.18 CEP15681.1 - 0.038 14.7 3.3 0.038 14.7 3.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WBP-1 PF11669.8 CEP15681.1 - 4.2 8.1 5.8 56 4.4 3.0 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 Thymidylat_synt PF00303.19 CEP15682.1 - 5.4e-116 386.4 0.0 6.1e-116 386.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Glyco_hydro_125 PF06824.11 CEP15683.1 - 2.1e-157 524.3 0.1 2.5e-157 524.0 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) ACBP PF00887.19 CEP15684.1 - 9.3e-24 83.5 0.1 2.8e-23 81.9 0.1 1.9 1 0 0 1 1 1 1 Acyl CoA binding protein SlyX PF04102.12 CEP15684.1 - 0.041 14.5 0.5 0.041 14.5 0.5 2.9 4 0 0 4 4 4 0 SlyX BCNT PF07572.12 CEP15684.1 - 0.29 11.3 0.1 0.29 11.3 0.1 2.8 3 0 0 3 3 3 0 Bucentaur or craniofacial development SKG6 PF08693.10 CEP15684.1 - 0.57 9.6 2.9 1 8.8 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DEAD PF00270.29 CEP15685.1 - 5.5e-48 163.1 0.1 2.1e-47 161.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP15685.1 - 3.5e-24 85.3 0.0 3e-23 82.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CEP15685.1 - 5.7e-19 68.1 0.4 1e-18 67.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CEP15685.1 - 9.9e-05 22.4 0.0 0.00026 21.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Tho2 PF11262.8 CEP15686.1 - 0.014 14.6 0.5 0.014 14.6 0.5 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3027 PF11228.8 CEP15686.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) ParB PF08775.10 CEP15686.1 - 2.9 8.4 6.7 15 6.1 0.7 2.3 2 0 0 2 2 2 0 ParB family MCM_bind PF09739.9 CEP15687.1 - 5.1e-112 375.3 8.8 1.7e-89 300.8 2.4 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Nrap_D6 PF17407.2 CEP15687.1 - 0.027 14.7 0.3 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Nrap protein domain 6 MCM_lid PF17855.1 CEP15687.1 - 0.15 12.5 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain HSP90 PF00183.18 CEP15688.1 - 1.7e-105 353.9 2.9 1.6e-101 340.7 0.3 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CEP15688.1 - 4.6e-11 42.7 0.2 1.1e-10 41.4 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CEP15688.1 - 3.2e-07 30.8 0.1 1.8e-06 28.4 0.2 2.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5491 PF17595.2 CEP15688.1 - 0.019 15.3 0.1 0.06 13.7 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5491) Exo_endo_phos PF03372.23 CEP15689.1 - 3.9e-07 29.8 0.1 7.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4064 PF13273.6 CEP15690.1 - 2.1 8.7 15.9 0.088 13.1 1.7 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF4064) CxC2 PF18803.1 CEP15691.1 - 0.00081 19.5 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF5039 PF16442.5 CEP15692.1 - 0.027 14.0 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) CENP-H PF05837.12 CEP15692.1 - 0.12 12.8 0.2 0.15 12.5 0.2 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NatB_MDM20 PF09797.9 CEP15697.1 - 6.2e-108 361.1 10.9 6.2e-108 361.1 10.9 2.1 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit BTAD PF03704.17 CEP15697.1 - 0.0059 17.1 0.6 0.037 14.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_14 PF13428.6 CEP15697.1 - 0.027 15.3 3.7 59 4.9 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat GCR1_C PF12550.8 CEP15697.1 - 0.049 14.0 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes TPR_12 PF13424.6 CEP15697.1 - 0.2 11.9 5.3 17 5.8 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat MATH PF00917.26 CEP15697.1 - 0.42 10.8 2.7 21 5.3 0.0 4.0 4 0 0 4 4 4 0 MATH domain TPR_10 PF13374.6 CEP15697.1 - 0.62 10.0 2.2 90 3.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2689 PF10894.8 CEP15698.1 - 0.083 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Exonuc_VII_L PF02601.15 CEP15699.1 - 0.00089 18.9 25.1 0.00089 18.9 25.1 2.6 2 0 0 2 2 2 1 Exonuclease VII, large subunit IBN_N PF03810.19 CEP15700.1 - 1.4e-15 56.9 0.3 1.1e-14 54.1 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CEP15700.1 - 1.6e-10 40.4 0.2 1.4e-09 37.3 0.0 2.5 3 0 0 3 3 3 1 Cse1 Xpo1 PF08389.12 CEP15700.1 - 0.00022 21.3 4.6 0.00026 21.1 0.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein NUC173 PF08161.12 CEP15700.1 - 0.0072 16.0 0.2 0.039 13.6 0.1 2.2 2 0 0 2 2 2 1 NUC173 domain RIX1 PF08167.12 CEP15700.1 - 0.28 10.9 6.5 0.13 12.0 0.2 3.3 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Aa_trans PF01490.18 CEP15701.1 - 2.3e-57 194.6 23.3 2.9e-57 194.2 23.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Metallophos PF00149.28 CEP15702.1 - 2e-38 132.9 0.0 2.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP15702.1 - 2.1e-22 79.3 0.7 3.5e-22 78.6 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 CEP15703.1 - 2.4e-55 187.8 0.0 3.5e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15703.1 - 1.5e-32 112.9 0.0 2.3e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CEP15703.1 - 0.028 14.1 0.0 1.2 8.7 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Proteasom_PSMB PF10508.9 CEP15704.1 - 1.3e-29 103.1 1.0 1.6e-29 102.8 1.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_M PF14666.6 CEP15704.1 - 0.00081 19.1 0.1 0.61 9.9 0.0 3.2 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CEP15704.1 - 0.0054 16.9 0.3 11 6.4 0.0 3.5 2 1 2 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 PRIMA1 PF16101.5 CEP15707.1 - 0.11 12.6 0.2 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Acyltransf_C PF16076.5 CEP15708.1 - 1.5e-10 41.0 0.0 4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CEP15708.1 - 4.6e-10 39.2 0.0 6.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Xan_ur_permease PF00860.20 CEP15709.1 - 5.1e-23 81.4 32.3 2.7e-21 75.7 31.8 2.7 2 1 0 2 2 2 2 Permease family DUF3956 PF13104.6 CEP15709.1 - 0.096 12.9 3.3 1.9 8.8 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3956) Exo_endo_phos PF03372.23 CEP15711.1 - 0.00093 18.8 0.1 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CAMSAP_CC1 PF17095.5 CEP15712.1 - 0.062 13.1 0.1 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Lsr2 PF11774.8 CEP15712.1 - 0.11 12.7 0.3 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Lsr2 Ribosomal_S2 PF00318.20 CEP15713.1 - 1.6e-62 210.6 0.0 1.6e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 AMP-binding PF00501.28 CEP15714.1 - 2.6e-42 144.9 0.0 5.9e-42 143.7 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CEP15714.1 - 1.8e-08 34.1 1.8 3.4e-08 33.3 1.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CEP15714.1 - 0.0055 17.7 0.0 0.013 16.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NADH_dh_m_C1 PF15088.6 CEP15714.1 - 0.45 10.2 4.2 1.1 9.0 4.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial F-box-like PF12937.7 CEP15716.1 - 3e-06 27.0 0.0 9.7e-06 25.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like RB_B PF01857.20 CEP15718.1 - 0.1 12.7 1.4 0.25 11.4 1.4 1.7 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain ECH_1 PF00378.20 CEP15719.1 - 1.9e-44 151.8 0.2 2.3e-44 151.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP15719.1 - 2.8e-32 112.5 0.3 3.3e-32 112.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SAM_2 PF07647.17 CEP15720.1 - 1.3e-05 25.2 0.1 3.1e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP15720.1 - 0.0016 18.8 0.2 0.0046 17.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.10 CEP15720.1 - 0.15 12.2 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif SLC35F PF06027.12 CEP15722.1 - 1.7e-55 188.6 14.5 2.6e-55 188.1 14.5 1.2 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CEP15722.1 - 3.1e-08 33.9 19.0 0.00064 19.9 1.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CEP15722.1 - 1.5e-07 30.7 2.2 2.2e-07 30.1 2.2 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CEP15722.1 - 0.0034 16.6 11.0 0.0063 15.7 11.0 1.4 1 1 0 1 1 1 1 UAA transporter family YL1 PF05764.13 CEP15722.1 - 0.7 10.0 7.6 1.1 9.3 7.1 1.7 1 1 0 1 1 1 0 YL1 nuclear protein UCH PF00443.29 CEP15723.1 - 1.7e-49 168.7 1.3 2.5e-49 168.1 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP15723.1 - 1.5e-21 77.3 1.7 2.6e-21 76.6 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CEP15723.1 - 0.013 15.0 9.0 13 5.2 9.0 2.9 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3716 PF12511.8 CEP15723.1 - 0.28 11.3 4.5 0.85 9.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) Ribosomal_L22e PF01776.17 CEP15724.1 - 5.8e-49 165.0 1.7 6.8e-49 164.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HTH_Tnp_Tc3_2 PF01498.18 CEP15725.1 - 5.3e-06 26.6 0.0 1.7e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 CEP15725.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix RVT_1 PF00078.27 CEP15726.1 - 5.3e-19 68.6 0.1 9e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM154 PF15102.6 CEP15727.1 - 0.073 13.0 0.1 0.073 13.0 0.1 4.3 3 1 2 5 5 5 0 TMEM154 protein family UPF0160 PF03690.13 CEP15728.1 - 4.2e-133 443.9 0.0 4.7e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Integrase_H2C2 PF17921.1 CEP15729.1 - 5.4e-08 32.8 2.1 7.1e-08 32.4 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP15729.1 - 0.049 13.9 0.1 0.098 12.9 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger AAA PF00004.29 CEP15730.1 - 2.3e-17 63.7 0.0 6.9e-17 62.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEP15730.1 - 2.8e-15 56.8 0.1 6.5e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 CEP15730.1 - 0.00015 22.2 0.1 0.001 19.5 0.0 2.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CEP15730.1 - 0.00033 20.7 0.0 0.00079 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP15730.1 - 0.00047 19.9 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CEP15730.1 - 0.00053 19.5 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CEP15730.1 - 0.0015 19.1 0.0 0.0083 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEP15730.1 - 0.0016 18.2 3.2 0.0019 18.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CEP15730.1 - 0.0023 17.7 0.0 0.0065 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEP15730.1 - 0.006 17.0 0.0 0.023 15.1 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CEP15730.1 - 0.0064 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CEP15730.1 - 0.0077 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 CEP15730.1 - 0.0095 15.7 0.2 0.024 14.4 0.0 1.7 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein Sigma54_activ_2 PF14532.6 CEP15730.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CEP15730.1 - 0.012 15.4 0.0 0.055 13.2 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CEP15730.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_6 PF12774.7 CEP15730.1 - 0.018 14.0 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 CEP15730.1 - 0.027 14.7 0.3 0.18 12.1 0.0 2.5 3 1 0 3 3 3 0 AAA domain PPV_E1_C PF00519.17 CEP15730.1 - 0.055 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Papillomavirus helicase NACHT PF05729.12 CEP15730.1 - 0.056 13.3 0.0 0.38 10.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 CEP15730.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP15730.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain B56 PF01603.20 CEP15731.1 - 1.6e-171 570.9 7.0 2.2e-171 570.4 7.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CEP15731.1 - 0.029 14.3 2.6 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RraB PF06877.11 CEP15731.1 - 0.05 14.3 0.3 0.15 12.8 0.3 1.8 1 0 0 1 1 1 0 Regulator of ribonuclease activity B RHINO PF15319.6 CEP15731.1 - 0.88 9.6 10.3 0.083 12.9 5.5 1.8 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein UDPGT PF00201.18 CEP15732.1 - 7.7e-27 94.2 0.0 1.1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEP15732.1 - 8.9e-06 25.8 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DDE_3 PF13358.6 CEP15733.1 - 8.9e-22 77.4 0.0 3.3e-09 36.7 0.0 3.5 3 1 1 4 4 4 3 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP15733.1 - 4.8e-05 23.5 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 CEP15733.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix RelB PF04221.12 CEP15733.1 - 0.099 12.6 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 RelB antitoxin HTH_40 PF14493.6 CEP15733.1 - 0.17 12.4 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_28 PF02636.17 CEP15734.1 - 5.2e-76 255.7 0.0 6.3e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3232 PF11554.8 CEP15734.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Noc2 PF03715.13 CEP15735.1 - 1.4e-104 349.6 4.4 1.4e-104 349.6 4.4 1.7 2 0 0 2 2 2 1 Noc2p family Pecanex_C PF05041.15 CEP15735.1 - 0.00038 20.1 0.1 0.067 12.8 0.1 2.4 2 0 0 2 2 2 2 Pecanex protein (C-terminus) DEAD PF00270.29 CEP15736.1 - 4.3e-40 137.3 0.1 2.1e-39 135.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP15736.1 - 1.3e-20 73.7 0.2 8.7e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HIT PF04438.16 CEP15736.1 - 0.00056 19.7 0.2 0.00089 19.1 0.2 1.3 1 0 0 1 1 1 1 HIT zinc finger T4SS-DNA_transf PF02534.14 CEP15736.1 - 0.049 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer FMN_bind_2 PF04299.12 CEP15736.1 - 0.079 12.7 0.5 0.31 10.7 0.0 2.1 3 0 0 3 3 3 0 Putative FMN-binding domain Lactamase_B_2 PF12706.7 CEP15737.1 - 3.5e-32 111.5 0.0 6.6e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP15737.1 - 2.7e-14 53.4 0.0 5.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CEP15737.1 - 0.00067 19.7 0.1 0.36 10.8 0.1 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PhaP_Bmeg PF09602.10 CEP15737.1 - 0.15 11.9 0.2 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ABC_tran PF00005.27 CEP15738.1 - 7.7e-46 156.0 0.0 6.5e-23 81.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CEP15738.1 - 8.2e-15 55.4 0.4 1.6e-05 24.9 0.2 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP15738.1 - 4e-14 52.6 0.1 6.9e-05 22.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CEP15738.1 - 1.3e-07 31.7 0.0 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CEP15738.1 - 3e-07 30.8 0.8 0.074 13.3 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_28 PF13521.6 CEP15738.1 - 4e-07 30.4 0.0 0.021 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CEP15738.1 - 5.3e-07 30.1 0.1 0.1 13.0 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CEP15738.1 - 8.2e-07 28.7 0.0 0.028 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEP15738.1 - 8.3e-07 29.1 0.0 0.0068 16.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CEP15738.1 - 1.6e-06 28.6 0.1 0.036 14.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 CEP15738.1 - 2.8e-06 26.5 0.1 0.016 14.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CEP15738.1 - 1.5e-05 25.5 0.1 0.031 14.7 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 CEP15738.1 - 2.6e-05 24.0 0.0 0.67 9.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CEP15738.1 - 3.4e-05 24.2 0.0 0.43 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Chromo PF00385.24 CEP15738.1 - 5.8e-05 22.9 0.2 0.00018 21.3 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 CEP15738.1 - 6.9e-05 23.4 13.7 0.016 15.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 CEP15738.1 - 7.8e-05 22.9 0.0 0.31 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CEP15738.1 - 0.0001 21.5 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 CEP15738.1 - 0.00012 21.9 1.9 0.25 11.0 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.12 CEP15738.1 - 0.0002 21.3 0.0 0.38 10.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 CEP15738.1 - 0.0011 19.2 0.1 0.47 10.5 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_14 PF13173.6 CEP15738.1 - 0.0011 19.0 0.0 0.88 9.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 CEP15738.1 - 0.0012 18.8 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain HEAT_2 PF13646.6 CEP15738.1 - 0.0015 18.9 0.2 11 6.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats ATP-synt_ab PF00006.25 CEP15738.1 - 0.0045 16.7 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CEP15738.1 - 0.0045 16.7 0.0 3.4 7.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CEP15738.1 - 0.0085 15.9 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 CEP15738.1 - 0.0088 15.3 0.1 0.82 8.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 CEP15738.1 - 0.0092 16.1 0.0 0.74 9.8 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 CEP15738.1 - 0.011 15.5 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CEP15738.1 - 0.012 14.3 0.4 10 4.6 0.0 3.7 3 1 0 4 4 4 0 AAA domain AAA_27 PF13514.6 CEP15738.1 - 0.013 15.1 1.3 4.8 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 CEP15738.1 - 0.013 15.4 0.0 4.3 7.2 0.0 3.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CEP15738.1 - 0.014 14.7 0.2 9 5.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.14 CEP15738.1 - 0.014 15.4 0.1 6.4 6.8 0.0 3.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ParcG PF10274.9 CEP15738.1 - 0.015 15.5 0.4 2.5 8.2 0.0 2.9 2 1 1 3 3 3 0 Parkin co-regulated protein SbcCD_C PF13558.6 CEP15738.1 - 0.017 15.3 0.0 2.3 8.5 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 CEP15738.1 - 0.018 14.5 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CEP15738.1 - 0.023 14.6 0.1 2.4 8.0 0.1 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 CEP15738.1 - 0.03 13.9 0.2 5.6 6.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 CEP15738.1 - 0.04 13.6 0.0 0.85 9.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 CEP15738.1 - 0.044 13.5 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 CEP15738.1 - 0.063 12.8 0.0 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 CEP15738.1 - 0.08 12.9 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CEP15738.1 - 0.085 12.6 0.0 26 4.5 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein Septin PF00735.18 CEP15738.1 - 0.11 11.8 0.2 38 3.4 0.0 3.2 3 0 0 3 3 3 0 Septin HEAT PF02985.22 CEP15738.1 - 0.14 12.5 0.2 2.4 8.6 0.0 3.4 3 0 0 3 3 1 0 HEAT repeat Cytidylate_kin PF02224.18 CEP15738.1 - 0.18 11.5 0.9 3.3 7.4 0.0 2.9 2 1 0 3 3 3 0 Cytidylate kinase SAM_2 PF07647.17 CEP15739.1 - 1.6e-14 53.7 0.3 1.2e-13 51.0 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP15739.1 - 3.3e-11 43.5 1.9 1.8e-10 41.1 0.4 2.5 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) RA PF00788.23 CEP15739.1 - 5.8e-06 26.9 0.0 9.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CCDC53 PF10152.9 CEP15739.1 - 0.13 12.7 6.5 0.17 12.3 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2464 PF10240.9 CEP15739.1 - 2.1 7.9 6.5 0.56 9.7 2.2 1.9 2 0 0 2 2 2 0 Multivesicular body subunit 12 Acetyltransf_1 PF00583.25 CEP15742.1 - 1.6e-06 28.3 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP15742.1 - 0.0003 21.2 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP15742.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CEP15742.1 - 0.0068 16.3 0.0 0.0097 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP15742.1 - 0.055 13.6 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEP15742.1 - 0.12 13.0 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S27e PF01667.17 CEP15743.1 - 9.5e-29 98.9 3.6 9.5e-29 98.9 3.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S27 Acyltransferase PF01553.21 CEP15743.1 - 2.8e-12 46.4 0.0 7.5e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase TF_Zn_Ribbon PF08271.12 CEP15743.1 - 0.014 14.9 3.1 0.014 14.9 3.1 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding SPECT1 PF18680.1 CEP15743.1 - 0.065 12.9 0.3 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 IBR PF01485.21 CEP15743.1 - 0.47 10.7 2.0 1 9.6 0.9 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 CEP15743.1 - 0.77 9.8 5.9 0.24 11.4 1.2 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.6 CEP15743.1 - 1.6 8.8 5.7 0.73 9.8 2.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FYVE PF01363.21 CEP15743.1 - 1.6 8.9 5.2 24 5.2 2.9 2.3 2 0 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.16 CEP15744.1 - 2.8e-47 161.4 60.5 6.4e-37 127.3 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CEP15744.1 - 2.4e-13 49.3 4.5 8.3e-12 44.2 0.6 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family RVT_1 PF00078.27 CEP15745.1 - 4e-33 114.8 0.0 9e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP15745.1 - 2.8e-05 24.7 1.3 2.8e-05 24.7 1.3 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 CEP15745.1 - 0.00017 21.4 0.5 0.00061 19.6 0.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP15745.1 - 0.00082 19.0 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.6 CEP15745.1 - 5.6 6.8 10.5 16 5.4 4.7 2.9 3 0 0 3 3 3 0 Zinc knuckle DDE_3 PF13358.6 CEP15746.1 - 1.5e-27 96.2 0.0 4.9e-19 68.5 0.0 3.0 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_29 PF13551.6 CEP15746.1 - 0.0016 18.4 0.0 0.0039 17.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 CEP15746.1 - 0.0016 18.2 0.2 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 CEP15746.1 - 0.0027 17.5 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP15746.1 - 0.016 15.3 0.2 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP15746.1 - 0.15 12.3 0.5 0.41 11.0 0.1 1.9 2 0 0 2 2 2 0 Transposase zf-CRD PF17979.1 CEP15747.1 - 8.8e-16 58.4 3.2 1.1e-13 51.6 0.1 2.5 1 1 1 2 2 2 2 Cysteine rich domain with multizinc binding regions Prok-RING_4 PF14447.6 CEP15747.1 - 5.2e-06 26.2 3.5 5.2e-06 26.2 3.5 3.9 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CEP15747.1 - 1.5e-05 24.7 4.1 1.5e-05 24.7 4.1 3.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP15747.1 - 8.7e-05 22.5 2.9 8.7e-05 22.5 2.9 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEP15747.1 - 0.00021 21.6 4.1 0.00021 21.6 4.1 4.0 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_4 PF15227.6 CEP15747.1 - 0.0019 18.3 3.9 0.0019 18.3 3.9 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CEP15747.1 - 0.0026 17.7 4.3 0.0026 17.7 4.3 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP15747.1 - 0.015 15.2 5.1 0.015 15.2 5.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP15747.1 - 7.3 7.0 12.1 0.11 12.8 3.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain PAP_central PF04928.17 CEP15749.1 - 7.7e-114 378.8 0.0 1.2e-113 378.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEP15749.1 - 3.7e-45 153.6 0.3 9.6e-45 152.3 0.1 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEP15749.1 - 1.8e-10 40.9 0.0 4.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_1 PF00515.28 CEP15750.1 - 1.5e-24 84.8 0.0 3.8e-08 32.8 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP15750.1 - 2.3e-21 76.2 1.4 6.6e-07 29.9 0.1 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP15750.1 - 3.1e-21 73.7 0.1 6.1e-06 25.9 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP15750.1 - 5e-19 67.7 0.1 2.4e-06 27.1 0.0 4.6 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 CEP15750.1 - 4.9e-15 54.7 0.5 0.0012 19.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEP15750.1 - 5.3e-15 54.8 12.4 0.00088 19.9 0.1 5.9 6 2 2 8 8 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP15750.1 - 1e-14 53.4 0.0 0.00075 19.5 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP15750.1 - 1.4e-13 51.2 0.7 3.9e-06 27.3 0.4 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 CEP15750.1 - 4.2e-09 36.6 0.2 0.002 18.4 0.1 4.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP15750.1 - 1.2e-08 34.4 0.2 0.23 11.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP15750.1 - 1.2e-08 35.1 0.4 0.021 15.1 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP15750.1 - 6.2e-08 32.8 0.1 3 8.7 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP15750.1 - 3.1e-07 30.5 0.2 0.011 16.0 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CEP15750.1 - 3.6e-07 30.2 0.6 0.12 12.6 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEP15750.1 - 0.0069 15.6 1.1 1.2 8.3 0.6 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat DUF1641 PF07849.11 CEP15750.1 - 0.018 14.9 0.1 0.037 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4248 PF14053.6 CEP15750.1 - 0.025 14.6 0.2 0.11 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4248) MIT PF04212.18 CEP15750.1 - 0.033 14.3 0.0 3.6 7.7 0.0 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 CEP15750.1 - 0.037 14.0 0.0 18 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEP15750.1 - 0.054 13.4 2.1 1.9 8.4 0.5 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CEP15750.1 - 0.084 12.3 0.0 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 CEP15750.1 - 0.61 10.2 2.5 37 4.5 0.0 3.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat VTC PF09359.10 CEP15751.1 - 1.8e-101 339.2 0.1 1.8e-101 339.2 0.1 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CEP15751.1 - 2.3e-17 64.0 20.0 7.5e-08 32.7 0.1 4.3 3 1 1 4 4 4 4 SPX domain DUF202 PF02656.15 CEP15751.1 - 1.9e-16 60.3 3.6 1.9e-16 60.3 3.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Syntaxin-6_N PF09177.11 CEP15751.1 - 0.21 12.2 2.6 0.53 10.9 0.6 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF420 PF04238.12 CEP15751.1 - 0.75 10.1 3.4 0.67 10.2 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF420) NCBP3 PF10309.9 CEP15752.1 - 0.047 13.6 0.0 0.06 13.2 0.0 1.3 1 1 0 1 1 1 0 Nuclear cap-binding protein subunit 3 zf-RING_2 PF13639.6 CEP15753.1 - 1.8e-05 25.0 24.8 0.0027 18.0 17.0 3.3 2 1 1 3 3 3 1 Ring finger domain Mucin PF01456.17 CEP15753.1 - 4.2e-05 23.6 6.8 4.2e-05 23.6 6.8 2.6 3 0 0 3 3 3 1 Mucin-like glycoprotein zf-rbx1 PF12678.7 CEP15753.1 - 6e-05 23.2 19.1 0.0004 20.6 19.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP15753.1 - 0.015 15.2 14.4 0.015 15.2 14.4 3.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CEP15753.1 - 0.088 12.9 12.6 0.62 10.2 12.6 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt20 PF12090.8 CEP15753.1 - 0.094 12.3 8.0 0.5 9.9 0.1 2.3 2 0 0 2 2 2 0 Spt20 family Rad50_zn_hook PF04423.14 CEP15753.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 CEP15753.1 - 0.15 12.0 20.2 0.29 11.0 16.1 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 CEP15753.1 - 0.68 9.7 15.3 0.085 12.5 9.3 2.5 3 0 0 3 3 3 0 P-11 zinc finger zf-RING_4 PF14570.6 CEP15753.1 - 1.4 8.7 12.9 0.3 10.9 8.1 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CEP15753.1 - 2 8.6 12.5 0.17 12.0 6.6 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF4834 PF16118.5 CEP15753.1 - 2.7 9.0 8.7 2.4 9.2 2.4 3.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4834) zf-RING_UBOX PF13445.6 CEP15753.1 - 7.8 6.6 22.1 0.18 11.8 8.8 3.5 3 1 0 3 3 3 0 RING-type zinc-finger DUF2561 PF10812.8 CEP15753.1 - 9.8 6.1 7.6 8.4 6.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) Cornichon PF03311.14 CEP15754.1 - 7.2e-48 161.9 8.2 1.4e-47 161.0 8.2 1.5 1 0 0 1 1 1 1 Cornichon protein PAP_assoc PF03828.19 CEP15754.1 - 3.3e-16 59.2 0.1 8.5e-16 57.9 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEP15754.1 - 4e-05 23.8 0.0 8.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CEP15754.1 - 0.002 17.9 0.0 0.0066 16.2 0.0 1.9 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 CEP15754.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase tRNA-synt_2b PF00587.25 CEP15755.1 - 3.5e-38 131.3 0.0 5.7e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEP15755.1 - 5.5e-10 39.3 0.1 2e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Ysc84 PF04366.12 CEP15756.1 - 5e-42 142.7 1.4 5.5e-42 142.5 0.1 1.7 2 1 0 2 2 2 1 Las17-binding protein actin regulator Pkinase PF00069.25 CEP15757.1 - 1.2e-68 231.4 0.0 1.5e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15757.1 - 1.9e-36 125.7 0.0 2.4e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15757.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP15757.1 - 0.00019 20.9 1.4 0.00031 20.2 1.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP15757.1 - 0.0015 17.4 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEP15757.1 - 0.0029 17.6 1.0 0.0059 16.6 0.1 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP15757.1 - 0.0071 15.3 0.9 0.015 14.3 0.9 1.6 1 1 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CEP15757.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 CEP15757.1 - 0.1 11.6 0.3 0.15 11.0 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GSIII_N PF12437.8 CEP15758.1 - 3.2e-67 225.2 0.3 5.4e-67 224.4 0.3 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 CEP15758.1 - 1e-41 141.5 1.2 2.1e-41 140.4 1.2 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 CEP15758.1 - 1.2e-21 77.1 0.0 5.4e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain TAL_effector PF03377.13 CEP15758.1 - 0.13 12.6 0.4 7.5 7.0 0.0 3.2 3 0 0 3 3 3 0 TAL effector repeat 14-3-3 PF00244.20 CEP15759.1 - 3.7e-93 311.1 8.6 5.7e-93 310.5 8.6 1.2 1 0 0 1 1 1 1 14-3-3 protein FapA PF03961.13 CEP15759.1 - 0.023 13.3 0.2 0.031 12.9 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ima1_N PF09779.9 CEP15759.1 - 0.033 15.0 0.8 0.58 11.0 0.1 2.4 2 1 0 2 2 2 0 Ima1 N-terminal domain FliM PF02154.15 CEP15759.1 - 0.047 13.6 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF5588 PF17826.1 CEP15760.1 - 0.00051 19.0 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) PspB PF06667.12 CEP15760.1 - 0.096 12.8 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 Phage shock protein B IucA_IucC PF04183.12 CEP15762.1 - 6.1e-25 88.2 0.0 1.6e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 IucA / IucC family FhuF PF06276.12 CEP15762.1 - 1.5e-12 48.2 0.0 2.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter PPR_3 PF13812.6 CEP15763.1 - 3.7e-29 100.6 0.6 0.00011 22.2 0.0 6.3 5 1 2 7 7 6 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 CEP15763.1 - 7e-29 99.8 5.1 2.4e-06 27.6 0.0 7.8 4 2 4 8 8 8 6 PPR repeat family PPR_long PF17177.4 CEP15763.1 - 1.1e-22 80.4 2.2 5.4e-09 35.7 1.8 3.9 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEP15763.1 - 6.3e-20 70.0 5.6 0.0028 17.8 0.0 7.6 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.7 CEP15763.1 - 4.4e-10 39.1 0.3 0.12 12.1 0.0 5.8 5 0 0 5 5 5 4 PPR repeat RPN7 PF10602.9 CEP15763.1 - 0.00046 20.0 0.2 0.028 14.1 0.0 3.4 2 2 2 4 4 4 1 26S proteasome subunit RPN7 ATP13 PF12921.7 CEP15763.1 - 0.032 14.1 0.1 33 4.4 0.0 4.1 2 1 2 4 4 4 0 Mitochondrial ATPase expression DUF5354 PF17305.2 CEP15763.1 - 0.035 14.3 0.2 0.16 12.2 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5354) Clathrin PF00637.20 CEP15763.1 - 0.044 13.6 2.5 14 5.5 0.5 4.6 3 2 3 6 6 6 0 Region in Clathrin and VPS TPR_7 PF13176.6 CEP15763.1 - 0.13 12.3 2.1 52 4.2 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP15763.1 - 0.24 11.7 6.6 20 5.5 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Cofilin_ADF PF00241.20 CEP15766.1 - 3.8e-22 78.4 0.0 4.3e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 CEP15766.1 - 0.13 12.9 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Collagenase NinB PF05772.12 CEP15767.1 - 0.026 14.4 0.1 7 6.5 0.0 2.6 2 0 0 2 2 2 0 NinB protein Cuticle_3 PF11018.8 CEP15767.1 - 5 7.3 7.4 3.6 7.8 1.2 2.5 2 0 0 2 2 2 0 Pupal cuticle protein C1 SQS_PSY PF00494.19 CEP15770.1 - 5e-57 193.4 0.1 6.4e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase UBA_4 PF14555.6 CEP15770.1 - 0.24 11.2 1.0 0.74 9.7 0.0 2.4 3 0 0 3 3 3 0 UBA-like domain Amino_oxidase PF01593.24 CEP15771.1 - 9.6e-28 97.7 0.0 1.3e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP15771.1 - 7e-14 51.8 0.0 2e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP15771.1 - 1.9e-12 47.5 0.0 5.7e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP15771.1 - 4.5e-10 39.3 0.0 9.3e-08 31.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEP15771.1 - 3.2e-07 29.8 0.3 1.3e-05 24.5 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CEP15771.1 - 1.1e-05 25.0 0.1 4.4e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 CEP15771.1 - 0.00048 18.8 0.2 0.085 11.4 0.1 2.4 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_9 PF13454.6 CEP15771.1 - 0.00073 19.6 0.4 0.0094 15.9 0.1 2.8 2 2 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CEP15771.1 - 0.00099 17.9 0.1 0.0096 14.7 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 CEP15771.1 - 0.0017 17.5 1.9 0.0052 15.9 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CEP15771.1 - 0.0022 18.5 1.8 0.091 13.3 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CEP15771.1 - 0.0028 16.9 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CEP15771.1 - 0.0054 16.0 0.1 0.0081 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CEP15771.1 - 0.0099 15.2 0.0 0.06 12.6 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEP15771.1 - 0.013 14.3 1.0 0.4 9.5 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 CEP15771.1 - 0.027 14.9 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CEP15771.1 - 0.042 13.7 0.4 0.084 12.7 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEP15771.1 - 0.048 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CEP15771.1 - 0.056 13.1 0.5 0.14 11.8 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 CEP15771.1 - 0.057 12.9 0.5 0.095 12.1 0.5 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Lycopene_cycl PF05834.12 CEP15771.1 - 0.06 12.4 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CEP15771.1 - 0.072 12.4 0.5 0.13 11.5 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CEP15771.1 - 0.12 12.6 0.3 0.28 11.4 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 CEP15771.1 - 0.3 11.7 1.6 5.2 7.7 0.6 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent LRR_6 PF13516.6 CEP15772.1 - 4.2e-16 57.6 34.1 0.00031 20.5 2.3 10.6 10 1 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 CEP15772.1 - 7.7e-07 28.8 25.7 5.5 7.9 0.4 10.5 10 1 1 11 11 11 3 Leucine Rich Repeat DUF4957 PF16318.5 CEP15772.1 - 0.027 14.4 0.3 0.11 12.4 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4957) HK_sensor PF16750.5 CEP15772.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase Psu PF07455.11 CEP15772.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) TSCPD PF12637.7 CEP15772.1 - 0.15 12.4 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 TSCPD domain LRR_4 PF12799.7 CEP15772.1 - 0.25 11.8 48.6 0.89 10.1 5.3 8.2 5 2 6 11 11 11 0 Leucine Rich repeats (2 copies) FAM184 PF15665.5 CEP15774.1 - 0.028 14.2 0.4 0.047 13.5 0.4 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exo_endo_phos PF03372.23 CEP15776.1 - 3.4e-08 33.3 0.1 1e-07 31.8 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP15776.1 - 7.4e-05 22.6 0.1 0.00032 20.5 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 CEP15776.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FliT PF05400.13 CEP15776.1 - 0.037 14.8 2.3 0.11 13.4 2.3 1.8 1 0 0 1 1 1 0 Flagellar protein FliT SNAPc19 PF15497.6 CEP15776.1 - 0.061 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 RVT_1 PF00078.27 CEP15777.1 - 2.1e-27 96.1 0.0 6.1e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_bact_N PF12262.8 CEP15778.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal Thiol_cytolys_C PF17440.2 CEP15780.1 - 1.2 9.3 5.6 0.3 11.3 0.3 2.5 2 0 0 2 2 2 0 Thiol-activated cytolysin beta sandwich domain DDE_3 PF13358.6 CEP15781.1 - 3e-17 62.7 0.0 1.6e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP15781.1 - 0.045 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain MFS_1 PF07690.16 CEP15782.1 - 7.8e-15 54.6 5.9 9.1e-15 54.4 5.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Septin PF00735.18 CEP15783.1 - 4.8e-114 380.4 2.0 6.7e-114 379.9 2.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CEP15783.1 - 5.4e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP15783.1 - 1.3e-06 28.1 3.9 3.3e-05 23.5 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP15783.1 - 2.9e-06 27.3 0.6 6.8e-05 22.8 0.3 2.7 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 CEP15783.1 - 0.00029 21.0 0.3 0.00073 19.8 0.3 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 CEP15783.1 - 0.00039 20.0 1.5 0.0032 16.9 0.3 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.6 CEP15783.1 - 0.0015 18.8 2.0 0.0027 18.0 0.2 2.3 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 CEP15783.1 - 0.0042 16.4 0.2 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 AIG1 family KAP_NTPase PF07693.14 CEP15783.1 - 0.0057 15.9 0.2 0.023 13.9 0.2 2.1 1 1 0 1 1 1 1 KAP family P-loop domain Ras PF00071.22 CEP15783.1 - 0.0085 15.7 0.6 0.023 14.3 0.6 1.7 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.9 CEP15783.1 - 0.012 15.4 1.8 0.24 11.1 0.3 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 CEP15783.1 - 0.014 14.4 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 CEP15783.1 - 0.017 14.8 0.6 0.055 13.2 0.6 2.0 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CEP15783.1 - 0.027 13.8 0.8 0.071 12.5 0.0 2.1 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 CEP15783.1 - 0.03 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 CEP15783.1 - 0.032 13.7 0.3 0.062 12.8 0.3 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CEP15783.1 - 0.039 14.5 1.9 0.084 13.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CEP15783.1 - 0.04 14.3 0.1 0.14 12.6 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CEP15783.1 - 0.043 14.2 0.2 0.16 12.4 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 CEP15783.1 - 0.08 13.1 0.4 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEP15783.1 - 0.087 12.2 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CEP15783.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 CEP15783.1 - 1.1 9.2 10.6 5 7.2 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Lectin_N PF03954.14 CEP15783.1 - 5 6.9 7.0 0.59 9.9 1.9 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Kinesin PF00225.23 CEP15784.1 - 9e-97 324.0 0.0 1.3e-96 323.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEP15784.1 - 8.5e-18 64.7 0.0 2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DAHP_synth_1 PF00793.20 CEP15785.1 - 4.1e-103 344.0 0.0 4.8e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DSS1_SEM1 PF05160.13 CEP15786.1 - 8.5e-22 77.0 23.8 8.5e-22 77.0 23.8 1.8 1 1 1 2 2 2 1 DSS1/SEM1 family DUF2947 PF11163.8 CEP15786.1 - 0.039 13.8 11.8 0.049 13.5 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Cwf_Cwc_15 PF04889.12 CEP15786.1 - 0.56 9.9 17.1 0.63 9.7 17.1 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MMR_HSR1 PF01926.23 CEP15788.1 - 1.4e-18 67.0 1.4 3.2e-14 53.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP15788.1 - 1.2e-09 37.8 0.7 3e-06 26.9 0.1 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 CEP15788.1 - 1.5e-05 24.6 2.9 9.6e-05 22.0 0.0 3.1 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP15788.1 - 0.00017 21.6 7.8 0.011 15.6 0.1 2.8 2 1 0 3 3 3 2 RsgA GTPase cobW PF02492.19 CEP15788.1 - 0.034 13.8 0.3 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CEP15788.1 - 0.044 13.8 0.8 0.044 13.8 0.8 4.2 3 2 1 4 4 4 0 Dynamin family GN3L_Grn1 PF08701.11 CEP15788.1 - 0.086 13.0 14.1 0.084 13.0 7.8 2.5 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase UPF0767 PF15990.5 CEP15788.1 - 0.092 12.9 0.1 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 UPF0767 family Roc PF08477.13 CEP15788.1 - 0.41 10.9 4.0 12 6.1 0.1 3.5 2 1 2 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CEP15788.1 - 0.58 10.7 0.0 0.58 10.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ribosomal_S30 PF04758.14 CEP15791.1 - 0.00079 19.6 0.3 0.0021 18.2 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S30 NOG1 PF06858.14 CEP15791.1 - 0.1 12.4 0.1 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) HTH_29 PF13551.6 CEP15792.1 - 0.011 15.8 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.6 CEP15793.1 - 1.9e-12 47.2 0.0 6.6e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Kelch_6 PF13964.6 CEP15794.1 - 1.3e-16 60.2 2.4 2.5e-05 24.4 0.1 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CEP15794.1 - 2.4e-16 59.6 6.8 9.9e-10 38.5 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP15794.1 - 1.1e-15 57.2 0.2 5.3e-06 26.3 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CEP15794.1 - 8e-13 47.8 0.6 0.0023 17.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CEP15794.1 - 4e-12 45.5 0.7 0.0017 17.9 0.0 3.7 3 0 0 3 3 3 3 Kelch motif BTB PF00651.31 CEP15794.1 - 1.9e-09 37.7 0.1 3.7e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CEP15794.1 - 7.7e-09 35.4 3.8 0.005 16.8 0.0 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain SUIM_assoc PF16619.5 CEP15794.1 - 0.0015 18.5 0.0 0.015 15.4 0.0 2.7 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Rab3-GTPase_cat PF13890.6 CEP15795.1 - 0.016 14.9 0.1 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit WD40 PF00400.32 CEP15796.1 - 5.5e-12 46.0 4.6 0.0013 19.5 0.1 5.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15796.1 - 2.9e-05 24.3 0.0 2.3 8.6 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP15796.1 - 0.0025 17.7 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CEP15796.1 - 0.014 15.3 0.0 0.72 9.9 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Macoilin PF09726.9 CEP15796.1 - 1.6 7.2 11.7 2.6 6.5 11.7 1.2 1 0 0 1 1 1 0 Macoilin family Corona_NS2 PF04753.12 CEP15798.1 - 0.02 15.5 0.0 1.1 9.9 0.0 2.1 1 1 1 2 2 2 0 Coronavirus non-structural protein NS2 Response_reg PF00072.24 CEP15798.1 - 0.058 13.6 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain MciZ PF13072.6 CEP15798.1 - 0.085 12.7 0.1 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 Mother cell inhibitor of FtsZ Pirin_C PF05726.13 CEP15799.1 - 2.6e-32 111.3 0.0 1.3e-30 105.8 0.0 2.5 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Pirin PF02678.16 CEP15799.1 - 7e-32 109.6 0.1 1.2e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 CEP15799.1 - 0.013 15.1 1.2 0.036 13.8 0.3 2.2 2 0 0 2 2 2 0 Cupin domain Cupin_3 PF05899.12 CEP15799.1 - 0.065 12.9 0.5 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) XAP5 PF04921.14 CEP15800.1 - 6.3e-86 288.3 11.9 6.3e-86 288.3 11.9 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF5406 PF17400.2 CEP15800.1 - 7.9 6.9 7.3 17 5.8 3.1 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5406) Peptidase_C65 PF10275.9 CEP15801.1 - 0.029 13.8 0.7 0.055 12.9 0.3 1.6 1 1 0 1 1 1 0 Peptidase C65 Otubain JmjC PF02373.22 CEP15802.1 - 2.2e-09 37.7 0.3 4.1e-08 33.6 0.3 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CEP15802.1 - 4.3e-07 29.9 6.6 2.2e-06 27.6 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain JHD PF17811.1 CEP15802.1 - 2.9e-06 27.8 3.2 5.5e-06 26.9 0.2 2.5 1 1 1 2 2 2 1 Jumonji helical domain PHD PF00628.29 CEP15802.1 - 5e-06 26.3 11.9 9.6e-06 25.4 11.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-RRPl_C4 PF17026.5 CEP15802.1 - 0.037 14.1 4.0 0.099 12.8 4.0 1.7 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 CEP15802.1 - 0.091 12.7 8.5 0.024 14.5 5.7 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_phi PF04931.13 CEP15802.1 - 0.11 10.6 23.2 0.19 9.8 23.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cupin_1 PF00190.22 CEP15802.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Cupin zf-RING_2 PF13639.6 CEP15802.1 - 0.57 10.6 7.8 0.98 9.8 7.8 1.4 1 0 0 1 1 1 0 Ring finger domain HTH_Tnp_Tc5 PF03221.16 CEP15803.1 - 6.7e-13 48.5 0.1 1.9e-12 47.0 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 CEP15803.1 - 0.00012 21.6 0.4 0.00032 20.3 0.4 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 CEP15803.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix MRP-L20 PF12824.7 CEP15803.1 - 0.01 16.0 1.3 0.01 16.0 1.3 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 HTH_36 PF13730.6 CEP15803.1 - 0.01 15.8 0.7 0.033 14.1 0.7 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 CEP15803.1 - 0.064 13.1 0.0 0.36 10.7 0.1 2.2 3 0 0 3 3 3 0 Homeodomain-like domain Nup192 PF11894.8 CEP15804.1 - 2.3e-198 661.6 38.7 2.9e-198 661.3 38.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1681 PF07933.14 CEP15805.1 - 1.3e-58 196.9 0.0 1.7e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CotH PF08757.11 CEP15806.1 - 1.4e-31 110.3 5.8 2.1e-31 109.6 5.8 1.2 1 0 0 1 1 1 1 CotH kinase protein DNA_binding_2 PF13724.6 CEP15806.1 - 0.079 13.4 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 DNA-binding domain DUF1325 PF07039.11 CEP15807.1 - 3.4e-36 124.2 2.6 3.4e-36 124.2 2.6 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CEP15807.1 - 3.6e-06 26.7 0.1 1.1e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CEP15807.1 - 0.00017 21.6 1.7 0.2 11.7 0.7 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4537) Agenet PF05641.12 CEP15807.1 - 0.0016 18.8 1.6 3 8.4 0.0 3.0 3 0 0 3 3 3 2 Agenet domain DUF4819 PF16090.5 CEP15807.1 - 0.0028 17.7 0.2 0.33 11.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4819) LBR_tudor PF09465.10 CEP15807.1 - 0.0031 17.3 0.3 0.087 12.6 0.0 2.7 3 0 0 3 3 3 1 Lamin-B receptor of TUDOR domain Pep1_7 PF17232.2 CEP15807.1 - 0.043 14.3 1.8 9.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Elicitor peptide 1-7 Ploopntkinase3 PF18751.1 CEP15807.1 - 0.12 12.3 0.2 0.17 11.8 0.2 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Peroxin-13_N PF04088.13 CEP15807.1 - 0.59 10.4 2.9 2.7 8.2 2.9 1.9 1 1 0 1 1 1 0 Peroxin 13, N-terminal region WD40 PF00400.32 CEP15808.1 - 2.5e-40 135.7 19.8 3.1e-06 27.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP15808.1 - 2e-13 50.4 0.0 0.0085 16.4 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP15808.1 - 0.00042 20.2 0.0 0.51 10.2 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CEP15808.1 - 0.0028 17.1 0.0 4.3 6.6 0.0 3.4 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 CEP15808.1 - 0.067 11.8 0.1 6.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Atg14 PF10186.9 CEP15808.1 - 2.6 7.1 4.5 5 6.1 4.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 CEP15809.1 - 1.5e-10 41.0 5.8 1.5e-10 41.0 5.8 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP15809.1 - 5e-07 29.7 12.0 6.3e-07 29.4 7.9 2.1 1 1 1 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 CEP15809.1 - 0.0041 17.0 2.4 0.0059 16.5 2.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_Maf PF03131.17 CEP15809.1 - 0.0044 17.5 5.7 0.0069 16.9 5.7 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.15 CEP15809.1 - 0.0095 15.7 2.6 0.016 15.0 2.6 1.3 1 0 0 1 1 1 1 Septum formation initiator HAP1_N PF04849.13 CEP15809.1 - 0.02 14.1 2.5 0.028 13.6 2.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ZapB PF06005.12 CEP15809.1 - 0.14 12.6 6.0 0.2 12.1 5.4 1.5 1 1 0 1 1 1 0 Cell division protein ZapB BSP_II PF05432.11 CEP15810.1 - 0.61 9.7 18.3 2.1 8.0 18.3 1.9 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MBOAT PF03062.19 CEP15811.1 - 5.5e-49 167.4 30.0 6.6e-49 167.1 30.0 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1201 PF06716.11 CEP15811.1 - 0.19 11.8 4.4 0.34 11.0 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) MMR_HSR1 PF01926.23 CEP15812.1 - 1.2e-14 54.4 0.0 2.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP15812.1 - 0.053 13.0 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Complex1_49kDa PF00346.19 CEP15813.1 - 5e-121 402.9 0.0 7.9e-121 402.3 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CEP15813.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Nickel-dependent hydrogenase DDE_3 PF13358.6 CEP15814.1 - 1.8e-11 44.0 0.0 5.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease HIT PF01230.23 CEP15814.1 - 0.013 16.2 0.0 0.02 15.6 0.0 1.3 1 0 0 1 1 1 0 HIT domain Zn_Tnp_IS1595 PF12760.7 CEP15815.1 - 0.00037 20.4 1.2 0.00061 19.7 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain CxC3 PF18804.1 CEP15815.1 - 0.0092 15.8 0.2 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Anti-TRAP PF15777.5 CEP15815.1 - 0.011 15.6 0.3 0.34 10.9 0.1 2.1 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 CEP15815.1 - 0.033 14.6 0.1 0.05 14.0 0.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_10 PF10058.9 CEP15815.1 - 0.037 13.8 0.2 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2387 PF09526.10 CEP15815.1 - 0.05 13.8 0.9 1.3 9.3 0.9 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.13 CEP15815.1 - 0.24 11.5 2.7 0.68 10.0 2.7 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 CEP15815.1 - 0.27 11.5 3.1 3.7 7.9 0.4 2.2 1 1 0 2 2 2 0 TFIIH C1-like domain zf_UBZ PF18439.1 CEP15815.1 - 0.4 10.3 2.9 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Ribosomal_L37ae PF01780.19 CEP15815.1 - 0.57 10.3 3.8 9 6.5 0.4 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-ribbon_3 PF13248.6 CEP15815.1 - 1.1 8.8 5.5 8.1 6.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 CEP15815.1 - 1.2 9.0 6.3 16 5.3 0.5 2.9 3 0 0 3 3 3 0 InsA N-terminal domain tRNA-synt_1c PF00749.21 CEP15816.1 - 1.7e-110 368.8 0.3 2.3e-110 368.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CEP15816.1 - 7.5e-43 146.3 0.2 2.8e-42 144.5 0.2 1.9 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CEP15816.1 - 1.7e-35 122.5 0.0 5.3e-35 120.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CEP15816.1 - 1.5e-13 51.5 3.3 3.8e-13 50.2 3.3 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.22 CEP15817.1 - 2.8e-77 260.4 0.1 3.4e-77 260.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF5 PF04855.12 CEP15818.1 - 1.3e-66 224.8 0.6 1.3e-66 224.8 0.6 2.1 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 MFAP1 PF06991.11 CEP15819.1 - 5.1e-72 242.2 27.1 5.1e-72 242.2 27.1 2.4 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Ras PF00071.22 CEP15820.1 - 9.2e-58 194.4 0.3 1.1e-57 194.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP15820.1 - 2e-37 128.1 0.2 3e-37 127.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP15820.1 - 3.8e-19 68.8 0.1 5e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP15820.1 - 7.7e-09 35.2 0.0 9.7e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP15820.1 - 4e-07 30.1 0.0 6.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP15820.1 - 2.1e-05 24.1 0.1 3.4e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CEP15820.1 - 0.00016 22.1 0.1 0.00026 21.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEP15820.1 - 0.00087 19.2 0.9 0.22 11.4 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CEP15820.1 - 0.0085 15.3 0.5 0.078 12.1 0.1 1.7 1 1 1 2 2 2 1 G-protein alpha subunit TniB PF05621.11 CEP15820.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MCR_beta PF02241.18 CEP15820.1 - 0.06 13.0 0.1 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain AAA_22 PF13401.6 CEP15820.1 - 0.14 12.5 0.1 0.36 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain Ank_4 PF13637.6 CEP15821.1 - 1e-15 57.8 0.5 6.7e-10 39.3 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP15821.1 - 1.4e-13 51.2 0.3 6.7e-06 26.6 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP15821.1 - 1.2e-09 37.6 0.3 0.0035 17.7 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CEP15821.1 - 1e-07 32.1 1.4 0.0063 16.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP15821.1 - 4.2e-06 26.9 0.1 0.012 15.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 CEP15821.1 - 3e-05 23.8 0.2 0.00029 20.6 0.1 2.6 2 1 0 2 2 2 1 KilA-N domain gag-asp_proteas PF13975.6 CEP15822.1 - 0.0017 18.9 0.0 0.0059 17.1 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP15822.1 - 0.0059 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CEP15822.1 - 0.0066 16.7 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Raco_middle PF17651.1 CEP15822.1 - 0.077 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 RACo middle region GAT PF03127.14 CEP15822.1 - 0.22 11.9 1.7 0.39 11.1 0.6 2.0 1 1 1 2 2 2 0 GAT domain Sec61_beta PF03911.16 CEP15826.1 - 6.9e-18 64.4 0.7 8.3e-18 64.1 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family Glycogen_syn PF05693.13 CEP15827.1 - 0 1102.4 0.0 0 1102.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 CEP15827.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CEP15827.1 - 3.9e-07 29.8 0.0 3.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP15827.1 - 2.1e-06 28.2 0.0 0.0015 19.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEP15827.1 - 1.9e-05 24.8 0.1 3.4e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CEP15827.1 - 0.0026 18.2 0.0 0.0051 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Cullin_binding PF03556.15 CEP15828.1 - 2.4e-28 99.0 6.4 2.4e-28 99.0 6.4 1.9 1 1 1 2 2 2 1 Cullin binding NDK PF00334.19 CEP15829.1 - 5e-29 101.0 0.0 6.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PQ-loop PF04193.14 CEP15830.1 - 1.9e-33 114.0 5.0 1.5e-17 63.1 1.0 2.8 2 0 0 2 2 2 2 PQ loop repeat E1_dh PF00676.20 CEP15831.1 - 2.2e-120 401.1 0.1 2.7e-120 400.9 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CEP15831.1 - 0.0084 15.3 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 CEP15831.1 - 0.072 14.1 1.6 0.53 11.3 0.1 2.8 2 1 0 2 2 2 0 KRTAP type 7 family COMM_domain PF07258.14 CEP15831.1 - 0.097 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 COMM domain DUF155 PF02582.14 CEP15832.1 - 1.7e-56 191.1 0.8 2.9e-56 190.3 0.8 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FANCI_S4 PF14678.6 CEP15833.1 - 2.1e-63 213.8 10.3 2.1e-63 213.8 10.3 2.5 2 1 0 2 2 2 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 CEP15833.1 - 1.8e-34 119.1 1.5 1.8e-34 119.1 1.5 2.5 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S2 PF14676.6 CEP15833.1 - 1e-26 94.2 1.8 6.3e-19 68.9 0.1 4.2 2 1 1 3 3 3 2 FANCI solenoid 2 FANCI_S1 PF14675.6 CEP15833.1 - 8e-23 81.2 3.6 7.4e-20 71.5 3.7 3.6 1 1 0 1 1 1 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 CEP15833.1 - 9e-23 80.0 0.2 1.6e-21 76.0 0.1 3.3 2 0 0 2 2 2 1 FANCI helical domain 1 DUF4611 PF15387.6 CEP15833.1 - 0.17 12.2 2.7 0.53 10.5 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Maelstrom PF13017.6 CEP15833.1 - 0.21 11.2 7.0 0.022 14.5 1.3 2.3 2 0 0 2 2 2 0 piRNA pathway germ-plasm component W2 PF02020.18 CEP15834.1 - 6.4e-15 55.1 0.0 2.4e-14 53.2 0.0 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon PI3Ka PF00613.20 CEP15834.1 - 0.0022 17.4 0.6 0.005 16.3 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Rep_fac_C PF08542.11 CEP15835.1 - 3.9e-24 84.9 0.0 8.6e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 CEP15835.1 - 2.9e-12 47.1 0.0 5.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CEP15835.1 - 5.8e-12 45.7 0.0 4.8e-10 39.4 0.1 2.5 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CEP15835.1 - 5.1e-07 29.8 0.0 3.6e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP15835.1 - 2.6e-05 24.7 0.0 0.0011 19.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 CEP15835.1 - 0.00014 21.9 0.0 0.00035 20.5 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CEP15835.1 - 0.00018 21.8 0.1 0.86 9.9 0.1 2.6 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CEP15835.1 - 0.00099 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CEP15835.1 - 0.0019 17.6 0.0 0.013 14.9 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CEP15835.1 - 0.005 16.6 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CEP15835.1 - 0.0055 17.0 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_3 PF07726.11 CEP15835.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CEP15835.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CEP15835.1 - 0.029 14.3 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 CEP15835.1 - 0.04 13.5 0.0 0.22 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP15835.1 - 0.056 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 CEP15835.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TniB PF05621.11 CEP15835.1 - 0.099 12.0 0.0 9.2 5.6 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 CEP15835.1 - 0.11 12.8 0.1 0.41 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 CEP15836.1 - 7.7e-63 212.3 0.0 9.4e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15836.1 - 3.6e-21 75.6 0.0 2.3e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEP15836.1 - 1e-06 28.8 1.3 3e-06 27.3 0.3 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP15836.1 - 0.008 15.8 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CEP15836.1 - 0.009 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CEP15836.1 - 0.016 14.6 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHP PF02811.19 CEP15838.1 - 5e-06 26.9 0.0 6.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PHP domain Ribosomal_S5 PF00333.20 CEP15839.1 - 1e-28 99.1 0.8 2.1e-28 98.1 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CEP15839.1 - 2.3e-24 84.6 0.1 3.7e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 CEP15839.1 - 1.5 9.4 9.4 2.8 8.5 9.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FR47 PF08445.10 CEP15840.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CEP15840.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chorismate_bind PF00425.18 CEP15841.1 - 2.4e-97 325.6 0.0 4.9e-97 324.5 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CEP15841.1 - 1.4e-27 96.6 0.0 4.2e-26 91.9 0.0 3.0 3 2 0 3 3 3 1 Anthranilate synthase component I, N terminal region Hid1 PF12722.7 CEP15842.1 - 6.2e-234 778.8 5.1 7.4e-234 778.5 5.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CEP15842.1 - 2.5e-119 399.5 3.6 3.2e-119 399.2 3.6 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SUIM_assoc PF16619.5 CEP15842.1 - 0.0072 16.4 1.0 0.0072 16.4 1.0 3.4 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 RTTN_N PF14726.6 CEP15842.1 - 0.6 10.9 9.1 0.54 11.1 0.8 3.6 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning NDC10_II PF16787.5 CEP15843.1 - 1.6e-08 34.0 0.3 1.8e-08 33.8 0.3 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RSN1_7TM PF02714.15 CEP15844.1 - 6.3e-76 255.3 24.4 9.2e-76 254.7 24.4 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP15844.1 - 1.5e-34 119.8 0.6 3.2e-34 118.7 0.6 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEP15844.1 - 2.6e-34 118.3 0.9 2.6e-34 118.3 0.9 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CEP15844.1 - 5.5e-11 42.5 0.1 1.6e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 CEP15844.1 - 0.027 14.3 0.1 12 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3464 PF11947.8 CEP15844.1 - 0.13 12.0 0.4 1.9 8.2 0.0 2.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 UPF0242 PF06785.11 CEP15844.1 - 8.6 6.4 7.9 0.54 10.3 0.4 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus G-alpha PF00503.20 CEP15845.1 - 2.5e-103 346.0 4.3 7.3e-75 252.3 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 CEP15845.1 - 4.1e-15 55.7 0.7 2.5e-09 36.8 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP15845.1 - 0.00026 20.4 0.2 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP15845.1 - 0.0034 17.6 0.1 0.83 9.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CEP15845.1 - 0.065 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2985 PF11204.8 CEP15845.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) UCR_UQCRX_QCR9 PF05365.12 CEP15846.1 - 4.4e-28 97.0 4.0 4.9e-28 96.8 4.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ParA PF10609.9 CEP15847.1 - 1.3e-100 335.9 1.1 1.5e-100 335.7 1.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CEP15847.1 - 1.3e-12 47.9 0.0 2.8e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEP15847.1 - 6.1e-09 36.0 1.3 1.5e-06 28.2 0.2 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CEP15847.1 - 5.1e-07 29.2 0.0 7.7e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CEP15847.1 - 1.1e-05 25.0 0.2 0.00029 20.4 0.2 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 CEP15847.1 - 0.0012 18.1 1.9 0.006 15.8 0.8 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 CEP15847.1 - 0.028 14.0 2.4 0.067 12.8 2.4 1.6 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 CEP15847.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein PhnA_Zn_Ribbon PF08274.12 CEP15847.1 - 0.07 13.1 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon AAA_26 PF13500.6 CEP15847.1 - 0.23 11.2 1.2 0.9 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain CobA_CobO_BtuR PF02572.15 CEP15847.1 - 0.47 10.7 1.2 0.96 9.7 1.2 1.5 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP MULE PF10551.9 CEP15851.1 - 5.6e-06 26.7 0.7 5.6e-06 26.7 0.7 2.4 2 1 0 2 2 2 1 MULE transposase domain DDE_1 PF03184.19 CEP15851.1 - 0.0012 18.5 0.6 0.0026 17.4 0.6 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1892 PF08987.10 CEP15851.1 - 0.13 12.5 2.5 0.082 13.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1892) RVT_1 PF00078.27 CEP15852.1 - 1.1e-16 61.1 0.0 4e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP15852.1 - 1.2e-07 31.6 0.7 5.5e-07 29.4 0.7 2.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP15852.1 - 6.7e-06 25.8 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CEP15852.1 - 0.014 16.1 0.5 0.014 16.1 0.5 2.7 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase zf-CCHC_4 PF14392.6 CEP15852.1 - 0.45 10.3 6.5 0.27 11.0 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP15852.1 - 4.9 7.4 19.2 0.33 11.1 2.8 2.7 2 0 0 2 2 2 0 Zinc knuckle Herpes_TK PF00693.18 CEP15854.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DDE_3 PF13358.6 CEP15855.1 - 1.7e-27 96.0 0.0 3.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.18 CEP15855.1 - 3.9e-06 26.8 0.0 9.7e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 'Paired box' domain HTH_29 PF13551.6 CEP15855.1 - 1e-05 25.4 0.2 4.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CEP15855.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CEP15855.1 - 0.0008 20.0 0.0 0.011 16.3 0.0 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP15855.1 - 0.0045 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF1323 PF07037.11 CEP15855.1 - 0.016 15.6 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) DUF4322 PF14210.6 CEP15855.1 - 0.029 14.2 0.1 0.088 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) TrmB PF01978.19 CEP15855.1 - 0.06 13.2 0.2 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Thiolase_N PF00108.23 CEP15856.1 - 5.4e-75 252.1 5.9 9.8e-75 251.3 5.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP15856.1 - 1e-46 157.6 1.4 1.9e-46 156.7 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEP15856.1 - 0.071 12.7 4.1 0.22 11.1 2.4 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.21 CEP15857.1 - 3e-08 33.6 18.1 9.1e-07 28.9 10.0 2.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 CEP15857.1 - 7.1e-06 26.0 8.3 7.1e-06 26.0 8.3 3.2 2 1 1 3 3 3 2 Basic region leucine zipper SUIM_assoc PF16619.5 CEP15857.1 - 6e-05 23.0 1.5 6e-05 23.0 1.5 2.6 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Bile_Hydr_Trans PF04775.14 CEP15857.1 - 0.019 15.0 0.3 0.044 13.8 0.3 1.5 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Golgin_A5 PF09787.9 CEP15857.1 - 0.38 10.2 22.8 0.69 9.3 22.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Methyltransf_31 PF13847.6 CEP15858.1 - 1.9e-18 66.7 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP15858.1 - 5.7e-11 43.0 0.0 7.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP15858.1 - 1.4e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP15858.1 - 3.9e-08 33.9 0.0 6.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP15858.1 - 6.1e-08 32.4 0.0 7.5e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CEP15858.1 - 7.2e-08 33.0 0.0 1.1e-07 32.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CEP15858.1 - 4.4e-07 29.5 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 CEP15858.1 - 1.1e-05 25.0 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 CEP15858.1 - 2.9e-05 23.7 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CEP15858.1 - 0.00029 20.8 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CEP15858.1 - 0.00069 18.7 0.0 0.0014 17.7 0.0 1.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase AdoMet_MTase PF07757.13 CEP15858.1 - 0.0091 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 CEP15858.1 - 0.011 15.4 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 CEP15858.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 CEP15858.1 - 0.052 13.0 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 CEP15858.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EABR PF12180.8 CEP15858.1 - 0.13 11.9 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 Pox_MCEL PF03291.16 CEP15858.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PIF1 PF05970.14 CEP15859.1 - 2.7e-26 92.6 0.0 3.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Type_III_YscX PF09474.10 CEP15860.1 - 0.036 14.4 0.5 4.3 7.7 0.1 2.6 2 1 1 3 3 3 0 Type III secretion system YscX (type_III_YscX) Suc_Fer-like PF06999.12 CEP15862.1 - 6.5e-52 176.3 0.0 2.6e-48 164.5 0.0 2.1 1 1 0 1 1 1 1 Sucrase/ferredoxin-like ING PF12998.7 CEP15863.1 - 6.2e-10 39.6 0.7 6.2e-10 39.6 0.7 1.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEP15863.1 - 8.2e-06 25.6 7.7 1.5e-05 24.8 7.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP15863.1 - 0.00046 19.7 1.7 0.00091 18.7 1.7 1.5 1 0 0 1 1 1 1 PHD-finger CREPT PF16566.5 CEP15863.1 - 0.018 15.2 2.6 0.045 13.9 2.6 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MAS20 PF02064.15 CEP15863.1 - 0.021 14.9 0.3 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor zf-HC5HC2H PF13771.6 CEP15863.1 - 0.032 14.5 1.1 0.073 13.3 1.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain CCDC53 PF10152.9 CEP15863.1 - 0.06 13.8 0.6 0.089 13.2 0.6 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex EMC3_TMCO1 PF01956.16 CEP15863.1 - 0.61 9.8 2.2 2.6 7.7 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Cyclin_C_2 PF16899.5 CEP15864.1 - 6.4e-17 61.8 0.2 2.6e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CEP15864.1 - 3.4e-10 39.7 0.3 1.1e-09 38.1 0.8 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain CybS PF05328.12 CEP15864.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit TFIIB PF00382.19 CEP15864.1 - 0.089 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF3914 PF13053.6 CEP15866.1 - 0.091 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) F-box-like PF12937.7 CEP15867.1 - 8.3e-05 22.4 0.0 0.00023 21.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 CEP15868.1 - 1.9e-06 27.7 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L50 PF10501.9 CEP15868.1 - 0.069 13.3 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal subunit 39S RVT_1 PF00078.27 CEP15869.1 - 6e-05 22.7 0.1 9.9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 CEP15870.1 - 4.7e-41 140.3 0.0 1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CEP15870.1 - 4.4e-19 68.2 0.1 8.7e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CEP15870.1 - 2.3e-09 36.9 0.2 6.5e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CEP15870.1 - 1.4e-05 25.1 0.1 8.7e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP15870.1 - 2e-05 25.1 0.2 0.0061 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP15870.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CEP15870.1 - 0.00038 20.6 0.0 0.0029 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CEP15870.1 - 0.00047 20.4 0.3 0.0094 16.2 0.2 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CEP15870.1 - 0.0016 17.7 0.0 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 CEP15870.1 - 0.0017 17.9 0.1 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CEP15870.1 - 0.0042 16.5 0.1 0.017 14.5 0.1 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CEP15870.1 - 0.0049 16.7 0.1 0.38 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP15870.1 - 0.0055 16.9 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 CEP15870.1 - 0.018 14.4 0.4 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 CEP15870.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CEP15870.1 - 0.036 14.6 0.4 0.35 11.4 0.0 2.8 2 2 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CEP15870.1 - 0.049 13.7 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CEP15870.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CEP15870.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CEP15870.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1192 PF06698.11 CEP15870.1 - 0.16 12.1 1.1 0.51 10.4 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_24 PF13479.6 CEP15870.1 - 0.18 11.5 1.7 0.24 11.1 0.1 2.2 3 1 0 3 3 2 0 AAA domain FlxA PF14282.6 CEP15870.1 - 0.31 11.0 5.2 0.088 12.8 1.4 2.0 3 0 0 3 3 2 0 FlxA-like protein DLP_helical PF18709.1 CEP15870.1 - 0.46 9.6 4.7 0.21 10.8 1.7 1.7 2 0 0 2 2 2 0 Dynamin-like helical domain ArAE_2_N PF10337.9 CEP15871.1 - 5.9e-21 75.0 14.5 4.6e-14 52.3 0.0 3.9 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CEP15871.1 - 2.4e-15 56.8 31.2 2.5e-15 56.7 13.0 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CEP15871.1 - 4e-13 49.7 0.2 9.2e-13 48.6 0.1 1.6 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 CEP15871.1 - 9.3e-10 37.7 20.7 4.7e-09 35.4 9.0 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 CEP15871.1 - 0.0013 17.7 7.7 0.0013 17.7 7.7 3.4 3 1 0 3 3 3 1 Aluminium activated malate transporter C-C_Bond_Lyase PF15617.6 CEP15871.1 - 0.025 13.7 0.2 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold ox_reductase_C PF08635.10 CEP15871.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Blt1 PF12754.7 CEP15871.1 - 0.17 12.2 1.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Blt1 N-terminal domain DUF2205 PF10224.9 CEP15872.1 - 1.3e-08 34.7 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein MCC-bdg_PDZ PF10506.9 CEP15872.1 - 0.065 13.2 0.7 0.081 13.0 0.7 1.2 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Slu7 PF11708.8 CEP15872.1 - 0.068 12.9 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor FAR1 PF03101.15 CEP15873.1 - 0.0015 19.2 1.2 0.0015 19.2 1.2 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain SR-25 PF10500.9 CEP15873.1 - 0.21 11.2 16.2 0.56 9.8 16.2 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MitMem_reg PF13012.6 CEP15874.1 - 4.1e-27 94.8 2.4 6.5e-27 94.2 0.5 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CEP15874.1 - 1.4e-15 57.3 0.0 3.3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CEP15874.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) PUF PF00806.19 CEP15875.1 - 3.4e-45 149.2 9.2 2.3e-06 26.9 0.0 9.1 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat IFT20 PF14931.6 CEP15875.1 - 0.0052 16.9 5.4 0.0052 16.9 5.4 2.5 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 Ku_PK_bind PF08785.11 CEP15875.1 - 0.085 13.0 2.9 0.52 10.5 0.0 3.4 3 0 0 3 3 3 0 Ku C terminal domain like Pkinase PF00069.25 CEP15877.1 - 2.2e-09 37.1 0.0 3.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CEP15877.1 - 9.4e-09 34.8 0.0 0.035 14.4 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 CEP15877.1 - 9.6e-07 29.0 0.1 0.0006 19.9 0.0 2.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 CEP15877.1 - 0.00027 20.3 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 CEP15877.1 - 0.0025 18.3 0.0 2 9.0 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat YL1 PF05764.13 CEP15877.1 - 0.011 15.9 6.6 0.019 15.1 6.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Kinase-like PF14531.6 CEP15877.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.20 CEP15877.1 - 0.044 12.3 0.1 0.11 11.0 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region HEAT_2 PF13646.6 CEP15877.1 - 0.06 13.7 0.0 0.87 10.0 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats Nup_retrotrp_bd PF10599.9 CEP15877.1 - 2 9.1 6.4 1.3 9.8 4.0 2.1 2 0 0 2 2 2 0 Retro-transposon transporting motif DUF4203 PF13886.6 CEP15878.1 - 6.4e-31 107.6 37.6 4.4e-28 98.3 37.6 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) Sporozoite_P67 PF05642.11 CEP15878.1 - 0.013 13.6 1.6 0.018 13.1 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box-like PF12937.7 CEP15879.1 - 6.9e-08 32.3 0.1 1.6e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP15879.1 - 0.015 15.1 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 F-box domain DUF1091 PF06477.13 CEP15879.1 - 0.12 12.9 1.0 3.4 8.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1091) F-box_5 PF18511.1 CEP15879.1 - 0.17 11.5 0.4 11 5.7 1.5 2.6 2 0 0 2 2 2 0 F-box GDPD PF03009.17 CEP15880.1 - 5.4e-64 216.4 0.0 1.3e-63 215.2 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CEP15880.1 - 1.1e-28 99.6 0.0 3.9e-07 30.6 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP15880.1 - 3.6e-21 75.2 0.6 8.2e-07 29.5 0.0 5.7 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP15880.1 - 3.2e-20 70.1 3.4 0.012 16.0 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 CEP15880.1 - 1.1e-17 63.9 0.2 0.0041 17.4 0.0 6.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.19 CEP15880.1 - 1.4e-16 61.5 5.0 7.1e-11 42.7 0.1 4.4 3 2 2 5 5 5 2 SPX domain Ank PF00023.30 CEP15880.1 - 8.6e-12 44.9 7.4 0.00074 19.9 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Btz PF09405.10 CEP15881.1 - 1.1e-09 38.6 3.7 1.1e-09 38.6 3.7 5.5 4 2 1 5 5 5 1 CASC3/Barentsz eIF4AIII binding RabGAP-TBC PF00566.18 CEP15882.1 - 5.6e-26 91.5 0.0 5.6e-26 91.5 0.0 3.1 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Alpha_L_fucos PF01120.17 CEP15883.1 - 1.3e-83 281.4 4.0 1.8e-83 280.9 4.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Lipase_3 PF01764.25 CEP15884.1 - 8.9e-14 51.6 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 CEP15884.1 - 0.00023 21.4 0.0 0.00071 19.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain F_bP_aldolase PF01116.20 CEP15885.1 - 4.6e-92 308.5 0.0 5.1e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II S-methyl_trans PF02574.16 CEP15885.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Homocysteine S-methyltransferase UQ_con PF00179.26 CEP15887.1 - 4.8e-48 162.4 0.0 7.1e-48 161.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEP15887.1 - 0.00039 20.1 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CEP15887.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 CEP15887.1 - 0.048 14.0 0.0 0.091 13.1 0.0 1.5 1 1 0 1 1 1 0 RWD domain Macoilin PF09726.9 CEP15887.1 - 0.077 11.5 4.9 0.081 11.5 4.9 1.1 1 0 0 1 1 1 0 Macoilin family PCNP PF15473.6 CEP15887.1 - 0.43 11.3 10.7 0.7 10.6 10.7 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DUF3704 PF12488.8 CEP15887.1 - 4.4 7.0 6.8 23 4.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Roughex PF06020.11 CEP15889.1 - 0.87 8.6 8.0 1.5 7.9 8.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 CEP15889.1 - 1.2 9.1 21.1 0.39 10.7 17.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEP15889.1 - 1.5 8.4 22.6 0.61 9.7 18.4 2.0 2 0 0 2 2 2 0 Spt20 family 2-oxoacid_dh PF00198.23 CEP15890.1 - 1.9e-83 279.5 0.0 2.6e-83 279.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CEP15890.1 - 3.6e-18 65.2 0.5 7.2e-18 64.2 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CEP15890.1 - 2.1e-15 56.8 0.8 5.4e-15 55.4 0.8 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CEP15890.1 - 0.075 12.9 0.5 0.27 11.1 0.1 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like ATP19 PF11022.8 CEP15891.1 - 6.2e-22 77.7 0.4 7e-22 77.6 0.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DPBB_1 PF03330.18 CEP15892.1 - 1.3e-08 35.0 0.1 2.1e-08 34.3 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP15892.1 - 2e-05 24.4 1.4 2.9e-05 23.9 1.4 1.2 1 0 0 1 1 1 1 Barwin family DUF871 PF05913.11 CEP15892.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Barwin PF00967.17 CEP15893.1 - 3.2e-09 36.7 0.7 3.9e-09 36.4 0.7 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 CEP15893.1 - 2.3e-06 27.8 0.3 4.2e-06 26.9 0.3 1.5 1 1 0 1 1 1 1 Lytic transglycolase DUF5077 PF16871.5 CEP15893.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) MukB PF04310.12 CEP15893.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal Lsm_interact PF05391.11 CEP15893.1 - 1.2 8.7 5.0 18 5.0 0.1 2.3 2 0 0 2 2 2 0 Lsm interaction motif Barwin PF00967.17 CEP15894.1 - 1.2e-08 34.8 0.3 2.3e-08 33.9 0.3 1.4 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 CEP15894.1 - 1.1e-05 25.6 0.1 2.9e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Lytic transglycolase DPBB_1 PF03330.18 CEP15895.1 - 9.3e-10 38.7 1.2 1.1e-09 38.4 0.2 1.7 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEP15895.1 - 1.9e-06 27.7 0.5 2.3e-06 27.4 0.5 1.2 1 0 0 1 1 1 1 Barwin family DUF871 PF05913.11 CEP15895.1 - 0.028 13.6 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) MspA PF09203.11 CEP15896.1 - 0.0054 16.6 9.6 0.01 15.7 9.6 1.4 1 1 0 1 1 1 1 MspA DUF2715 PF10895.8 CEP15896.1 - 0.33 10.6 10.4 61 3.2 10.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) DUF1943 PF09172.11 CEP15896.1 - 0.33 10.1 5.2 5.6 6.1 5.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) Imm68 PF15583.6 CEP15896.1 - 3.5 7.8 5.6 5.7 7.1 1.2 2.3 1 1 1 2 2 2 0 Immunity protein 68 Pkinase PF00069.25 CEP15897.1 - 2.7e-62 210.5 0.0 2.4e-30 105.8 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15897.1 - 5.1e-27 94.8 0.0 3.1e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Glutaredoxin PF00462.24 CEP15899.1 - 5.5e-16 58.5 0.0 7.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CEP15899.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Filamin PF00630.19 CEP15899.1 - 0.035 14.9 0.1 0.04 14.7 0.1 1.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF4928 PF16280.5 CEP15899.1 - 0.13 11.5 0.2 0.16 11.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) DUF3808 PF10300.9 CEP15900.1 - 9e-61 206.1 0.5 8.8e-60 202.8 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) Pyr_redox_2 PF07992.14 CEP15901.1 - 7.9e-33 113.9 0.0 9.4e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP15901.1 - 5e-09 36.2 0.3 0.00038 20.1 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CEP15901.1 - 6.8e-09 36.2 0.0 0.0012 19.4 0.0 3.1 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP15901.1 - 1.9e-07 30.2 0.5 0.00027 19.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 CEP15901.1 - 1.4e-06 27.7 0.5 0.0062 15.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 CEP15901.1 - 2.1e-06 27.9 0.2 0.0013 19.0 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CEP15901.1 - 2.3e-06 27.7 0.2 0.041 13.9 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CEP15901.1 - 2.7e-06 26.9 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CEP15901.1 - 9.6e-06 24.7 0.2 0.0026 16.7 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 CEP15901.1 - 9.9e-06 25.0 0.0 0.086 12.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Sacchrp_dh_NADP PF03435.18 CEP15901.1 - 0.00061 20.1 0.4 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CEP15901.1 - 0.00098 19.4 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain ThiF PF00899.21 CEP15901.1 - 0.0013 18.2 0.1 1.5 8.2 0.0 2.7 3 0 0 3 3 3 2 ThiF family AlaDh_PNT_C PF01262.21 CEP15901.1 - 0.0053 16.1 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CEP15901.1 - 0.0055 16.3 0.2 0.28 10.7 0.1 2.6 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 CEP15901.1 - 0.0077 15.4 0.1 1.3 8.1 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CEP15901.1 - 0.0094 15.2 0.3 1.3 8.1 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.24 CEP15901.1 - 0.034 13.3 0.6 0.086 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 CEP15901.1 - 0.038 13.9 0.0 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CEP15901.1 - 0.051 12.6 0.1 6 5.8 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 CEP15901.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 CEP15901.1 - 0.12 12.4 0.6 2.2 8.4 0.0 2.5 3 0 0 3 3 2 0 lactate/malate dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 CEP15902.1 - 5.2e-17 62.1 0.0 7.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.23 CEP15903.1 - 7.6e-81 271.6 0.6 2e-50 171.6 0.0 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CEP15903.1 - 3.1e-16 59.6 0.1 9.7e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF5082 PF16888.5 CEP15903.1 - 0.35 11.2 3.8 15 5.9 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DDE_3 PF13358.6 CEP15904.1 - 4.1e-21 75.3 0.0 6.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 CEP15904.1 - 0.001 18.4 0.0 0.0026 17.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 CEP15904.1 - 0.004 16.9 0.4 0.0086 15.8 0.1 1.7 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 CEP15904.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Actin PF00022.19 CEP15905.1 - 2e-111 372.5 0.0 1.6e-110 369.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEP15905.1 - 0.14 11.0 0.0 1.4 7.7 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein AMP-binding_C PF13193.6 CEP15906.1 - 0.00021 22.2 0.0 0.00037 21.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_ab PF00006.25 CEP15907.1 - 1e-71 241.0 0.0 1.5e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CEP15907.1 - 2.6e-48 163.5 0.1 4.3e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CEP15907.1 - 4.5e-20 71.9 0.6 1.2e-19 70.6 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PX PF00787.24 CEP15908.1 - 2.3e-18 66.2 0.1 6.4e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 PX domain PCNA_N PF00705.18 CEP15909.1 - 5.1e-53 178.1 2.8 9.3e-53 177.3 1.2 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CEP15909.1 - 3.8e-52 175.8 0.2 5.8e-52 175.2 0.2 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CEP15909.1 - 5.2e-10 39.2 0.1 6.5e-10 38.9 0.1 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 CEP15909.1 - 2.1e-08 33.6 0.8 3.2e-07 29.7 0.8 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 CEP15909.1 - 0.00049 19.3 0.1 0.0032 16.6 0.0 1.9 2 0 0 2 2 2 1 Hus1-like protein Arrestin_C PF02752.22 CEP15910.1 - 1.2e-12 48.5 0.1 2.9e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP15910.1 - 1e-05 25.7 0.0 0.0009 19.3 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CEP15910.1 - 0.0041 16.4 0.3 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 Rgp1 Pkinase PF00069.25 CEP15911.1 - 4.4e-38 131.2 0.0 5.1e-13 49.0 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15911.1 - 1.9e-20 73.3 0.1 2.4e-07 30.3 0.0 4.1 4 1 0 4 4 4 3 Protein tyrosine kinase Snapin_Pallidin PF14712.6 CEP15911.1 - 0.73 10.3 5.8 1.4 9.4 2.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin GreA_GreB_N PF03449.15 CEP15911.1 - 1.8 8.8 5.7 0.41 10.8 0.3 2.6 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal SH3_9 PF14604.6 CEP15912.1 - 1.5e-09 37.5 0.0 2.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CEP15912.1 - 2.7e-06 26.9 0.0 5.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain CYYR1 PF10873.8 CEP15912.1 - 0.0016 18.9 4.8 0.0016 18.9 4.8 2.3 3 0 0 3 3 3 1 Cysteine and tyrosine-rich protein 1 SH3_2 PF07653.17 CEP15912.1 - 0.0036 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dscam_C PF12355.8 CEP15912.1 - 0.089 13.7 0.9 0.089 13.7 0.9 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Pkinase PF00069.25 CEP15913.1 - 1.4e-68 231.1 0.0 1.3e-66 224.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15913.1 - 6.3e-29 101.0 0.0 1.7e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP15913.1 - 7.5e-07 28.7 0.2 0.11 11.8 0.1 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.14 CEP15913.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP15913.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEP15913.1 - 0.18 11.7 0.0 3.6 7.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Methyltransf_5 PF01795.19 CEP15915.1 - 1.7e-75 254.4 0.1 2e-64 218.1 0.0 2.9 1 1 1 2 2 2 2 MraW methylase family Methyltransf_31 PF13847.6 CEP15915.1 - 0.013 15.3 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FragX_IP PF05994.11 CEP15915.1 - 0.053 11.6 0.0 0.16 10.0 0.0 1.7 2 0 0 2 2 2 0 Cytoplasmic Fragile-X interacting family PsbT PF01405.17 CEP15916.1 - 1 9.2 7.4 3.9 7.4 3.7 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre T protein CBFD_NFYB_HMF PF00808.23 CEP15917.1 - 3.9e-30 103.9 1.0 6.1e-30 103.3 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP15917.1 - 3.7e-06 27.3 0.2 3.7e-06 27.3 0.2 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CEP15917.1 - 0.00011 22.2 0.1 0.00016 21.8 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 CEP15917.1 - 0.001 19.1 0.4 0.0025 17.8 0.0 1.8 1 1 1 2 2 2 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CEP15917.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated LepB_N PF18640.1 CEP15917.1 - 0.035 13.7 0.9 0.072 12.7 0.3 1.7 1 1 1 2 2 2 0 LepB N-terminal domain CENP-X PF09415.10 CEP15917.1 - 0.1 13.0 0.2 0.1 13.0 0.2 1.8 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF4770 PF15994.5 CEP15917.1 - 0.18 12.0 3.4 0.81 9.9 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) Spt20 PF12090.8 CEP15917.1 - 5.2 6.6 13.5 7.1 6.2 13.5 1.4 1 1 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CEP15919.1 - 4.6e-80 270.6 9.7 3.6e-57 195.2 8.2 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 CEP15919.1 - 0.0078 16.5 6.1 0.018 15.3 6.1 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 CEP15919.1 - 0.051 13.9 3.1 0.13 12.6 0.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MobB PF03205.14 CEP15919.1 - 0.3 11.0 0.1 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArfGap PF01412.18 CEP15920.1 - 2.9e-06 27.3 0.1 8.1e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Acetyltransf_10 PF13673.7 CEP15921.1 - 8.3e-14 51.6 0.0 1.5e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP15921.1 - 3.8e-11 43.2 0.0 4.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP15921.1 - 1.5e-07 31.7 0.0 2.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 CEP15921.1 - 0.0004 21.0 0.0 0.0021 18.7 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP15921.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CEP15921.1 - 0.093 12.8 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3907 PF13047.6 CEP15922.1 - 0.0094 15.9 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3907) FeS_assembly_P PF01883.19 CEP15923.1 - 9e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein FolB PF02152.18 CEP15923.1 - 0.018 15.6 0.5 0.1 13.1 0.2 2.0 1 1 1 2 2 2 0 Dihydroneopterin aldolase Pkinase PF00069.25 CEP15924.1 - 6.3e-60 202.8 0.0 9e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15924.1 - 2e-41 142.0 0.0 3.5e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP15924.1 - 6.9e-19 68.0 0.4 6.4e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 CEP15924.1 - 0.00014 20.8 5.3 0.00071 18.5 5.3 2.1 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP15924.1 - 0.00034 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP15924.1 - 0.0075 15.6 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP15924.1 - 0.013 15.4 0.2 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RE_Eco29kI PF09517.10 CEP15924.1 - 0.16 11.5 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Eco29kI restriction endonuclease SCHIP-1 PF10148.9 CEP15924.1 - 0.19 11.4 3.4 0.37 10.4 3.4 1.4 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Pox_Ag35 PF03286.14 CEP15924.1 - 0.27 11.0 4.0 0.71 9.6 4.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3682 PF12446.8 CEP15924.1 - 0.31 11.5 9.2 0.77 10.2 9.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RRT14 PF17075.5 CEP15924.1 - 0.83 9.7 5.7 0.74 9.9 2.5 2.1 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 zf-RING_2 PF13639.6 CEP15925.1 - 1.7e-09 37.8 6.5 4.2e-09 36.6 6.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEP15925.1 - 1e-08 35.4 6.7 1.8e-08 34.6 6.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP15925.1 - 3.9e-07 29.8 3.4 3.9e-07 29.8 3.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP15925.1 - 4.1e-06 26.7 4.0 7.8e-06 25.7 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEP15925.1 - 1.7e-05 24.6 6.9 3.2e-05 23.7 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP15925.1 - 0.00046 20.0 1.4 0.00046 20.0 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP15925.1 - 0.00068 19.4 3.7 0.0015 18.4 3.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP15925.1 - 0.00096 19.2 2.3 0.0023 17.9 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CEP15925.1 - 0.0013 18.7 4.5 0.0031 17.5 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CEP15925.1 - 0.0027 17.4 0.5 0.0027 17.4 0.5 2.7 3 0 0 3 3 2 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 CEP15925.1 - 0.0052 16.4 6.0 0.048 13.3 6.0 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CEP15925.1 - 0.23 11.8 3.2 0.52 10.7 3.2 1.6 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CEP15925.1 - 0.67 10.2 5.8 2.1 8.6 5.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CEP15925.1 - 3.4 7.9 7.1 8 6.7 6.9 1.7 1 1 0 1 1 1 0 RING-variant domain BAR_2 PF10455.9 CEP15926.1 - 8.3e-51 172.8 2.7 2.5e-48 164.7 2.7 2.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CEP15926.1 - 6.9e-22 78.2 1.0 2.2e-21 76.6 1.0 1.7 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CEP15926.1 - 0.00025 20.8 0.4 0.0034 17.1 0.2 2.5 1 1 0 1 1 1 1 BAR domain of APPL family PAF PF15715.5 CEP15928.1 - 0.13 12.8 4.1 0.18 12.4 4.1 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain gag-asp_proteas PF13975.6 CEP15929.1 - 0.074 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP15929.1 - 0.17 12.6 0.0 0.44 11.2 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease FAR1 PF03101.15 CEP15931.1 - 0.0016 19.1 0.2 0.0033 18.1 0.2 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain SLATT_5 PF18160.1 CEP15932.1 - 0.013 14.8 1.7 0.013 14.8 1.7 3.6 5 0 0 5 5 5 0 SMODS and SLOG-associating 2TM effector domain family 5 ERGIC_N PF13850.6 CEP15932.1 - 2.8 8.4 7.8 2.4 8.5 0.1 3.9 3 1 1 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cnd2 PF05786.14 CEP15933.1 - 4.6e-135 452.2 34.9 1.9e-87 294.8 21.1 2.9 1 1 1 2 2 2 2 Condensin complex subunit 2 DUF2448 PF10476.9 CEP15933.1 - 1.2 9.0 2.7 3.4 7.5 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) RVT_1 PF00078.27 CEP15935.1 - 1e-29 103.7 0.0 2.4e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP15935.1 - 1.9e-07 31.7 3.7 5.2e-07 30.3 3.7 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Tho2 PF11262.8 CEP15936.1 - 0.053 12.7 2.6 0.13 11.4 1.4 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 bZIP_1 PF00170.21 CEP15937.1 - 7e-10 38.9 11.8 1.3e-09 38.0 11.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEP15937.1 - 2.2e-07 30.8 8.7 2.2e-07 30.8 8.7 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP15937.1 - 5.8e-05 23.5 6.3 5.8e-05 23.5 6.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor GIT_CC PF16559.5 CEP15937.1 - 0.0021 17.9 3.9 0.0025 17.6 2.2 2.1 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CEP15937.1 - 0.029 15.0 0.2 0.083 13.5 0.2 1.8 1 0 0 1 1 1 0 Initiation control protein YabA DUF641 PF04859.12 CEP15937.1 - 0.14 12.5 2.3 0.29 11.5 2.3 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 CEP15937.1 - 0.34 11.0 10.3 0.024 14.7 4.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 CEP15937.1 - 0.45 10.3 5.4 0.78 9.6 0.8 2.5 1 1 1 2 2 2 0 Septum formation initiator Sulfate_transp PF00916.20 CEP15938.1 - 2.6e-107 358.9 21.8 3.6e-107 358.4 21.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP15938.1 - 3.9e-10 39.4 0.0 7.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CEP15938.1 - 4.1e-05 23.8 0.1 7.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP15938.1 - 0.29 11.5 18.7 0.032 14.6 3.3 3.5 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily Autophagy_act_C PF03987.15 CEP15939.1 - 7.8e-21 74.4 2.6 1.4e-20 73.6 2.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Coleoptericin PF06286.11 CEP15939.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Coleoptericin RVT_1 PF00078.27 CEP15941.1 - 2.9e-25 89.1 0.1 4.8e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 CEP15942.1 - 3.6e-05 23.2 0.0 3.8e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 PIF1 PF05970.14 CEP15943.1 - 7e-44 150.5 0.0 7.8e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Sigma70_r4_2 PF08281.12 CEP15944.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 MerR_1 PF13411.6 CEP15944.1 - 0.011 15.8 0.1 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF4811 PF16069.5 CEP15944.1 - 0.02 14.8 1.2 0.026 14.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) HTH_32 PF13565.6 CEP15944.1 - 0.043 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEP15944.1 - 0.078 13.1 0.1 6.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.6 CEP15945.1 - 1.9e-18 66.6 0.0 2.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Amidinotransf PF02274.17 CEP15945.1 - 0.11 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase RT_RNaseH PF17917.1 CEP15947.1 - 8.5e-12 45.3 0.1 2.4e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP15947.1 - 5.9e-11 42.3 1.2 1.2e-10 41.3 1.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP15947.1 - 2.9e-09 36.7 5.4 1e-08 35.0 0.6 3.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CEP15947.1 - 2.6e-07 30.6 0.0 8.3e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEP15947.1 - 0.0003 20.9 1.9 0.00077 19.6 1.9 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Tudor-knot PF11717.8 CEP15947.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.7 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain ABC_membrane PF00664.23 CEP15949.1 - 3.5e-120 400.8 33.6 7e-66 222.7 20.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP15949.1 - 2.2e-67 225.8 1.4 2.2e-34 118.9 0.1 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CEP15949.1 - 2.7e-12 46.6 0.0 2.6e-05 23.8 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CEP15949.1 - 4.3e-08 32.4 0.2 0.0015 17.4 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CEP15949.1 - 3.2e-07 30.7 3.2 0.0015 18.8 0.3 3.7 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEP15949.1 - 7.1e-06 25.9 2.3 0.045 13.5 0.0 4.4 4 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 CEP15949.1 - 1.9e-05 24.6 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CEP15949.1 - 4.9e-05 23.8 7.6 0.033 14.6 0.5 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 CEP15949.1 - 6.9e-05 23.3 3.8 2.3 8.7 0.0 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEP15949.1 - 0.00026 20.3 0.1 0.48 9.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 CEP15949.1 - 0.00035 20.1 0.2 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 CEP15949.1 - 0.00043 19.5 0.2 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SRP54 PF00448.22 CEP15949.1 - 0.00046 19.9 0.1 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CEP15949.1 - 0.00057 20.1 6.6 0.39 11.0 0.9 4.3 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CEP15949.1 - 0.00059 19.5 4.2 0.47 10.2 0.5 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 CEP15949.1 - 0.0017 18.5 0.2 0.94 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CEP15949.1 - 0.0031 17.5 0.1 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 CEP15949.1 - 0.0085 16.1 0.3 3.2 7.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEP15949.1 - 0.011 16.3 0.0 3.9 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP15949.1 - 0.014 15.1 0.1 3.7 7.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CEP15949.1 - 0.034 13.3 0.1 0.84 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CEP15949.1 - 0.037 14.1 0.3 12 6.0 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 CEP15949.1 - 0.042 13.8 0.4 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 CEP15949.1 - 0.042 14.1 0.2 1.4 9.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CEP15949.1 - 0.063 13.7 0.4 5 7.6 0.0 3.3 4 0 0 4 4 2 0 RNA helicase ATP_bind_1 PF03029.17 CEP15949.1 - 0.093 12.5 0.3 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GMC_oxred_N PF00732.19 CEP15949.1 - 0.15 11.4 0.3 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase AAA_17 PF13207.6 CEP15949.1 - 0.17 12.3 0.3 22 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 CEP15949.1 - 1.6 9.2 7.9 10 6.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain Lyase_1 PF00206.20 CEP15950.1 - 1e-121 406.2 0.0 1.4e-121 405.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CEP15950.1 - 3.5e-27 94.6 0.0 8e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.17 CEP15950.1 - 0.044 13.4 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 B3/4 domain DUF4288 PF14119.6 CEP15950.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Zip PF02535.22 CEP15951.1 - 2.2e-60 204.6 9.4 2.6e-60 204.4 9.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.14 CEP15951.1 - 0.12 11.8 2.9 0.16 11.3 2.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Mntp PF02659.15 CEP15951.1 - 0.28 10.9 7.6 0.44 10.3 0.4 3.1 1 1 2 3 3 3 0 Putative manganese efflux pump DUF4448 PF14610.6 CEP15952.1 - 4.1e-05 23.5 0.5 9.8e-05 22.2 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Glycophorin_A PF01102.18 CEP15952.1 - 0.036 14.3 0.8 0.46 10.7 0.0 2.2 1 1 1 2 2 2 0 Glycophorin A DUF5305 PF17231.2 CEP15952.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SET PF00856.28 CEP15953.1 - 1.5e-05 25.5 0.1 2.4e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CEP15953.1 - 0.0019 18.2 14.2 0.0044 17.1 14.2 1.6 1 0 0 1 1 1 1 MYND finger DUF2164 PF09932.9 CEP15953.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) zf-C6H2 PF15801.5 CEP15953.1 - 0.26 11.6 11.1 0.57 10.5 11.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Aconitase PF00330.20 CEP15954.1 - 3.2e-138 461.6 0.0 4.1e-138 461.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP15954.1 - 1.3e-38 132.3 0.0 2.8e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 CEP15955.1 - 3e-164 547.4 0.0 3.8e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CEP15955.1 - 4.7e-40 136.9 0.0 1.1e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Pol_alpha_B_N PF08418.10 CEP15955.1 - 0.076 13.0 0.8 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L3 PF00297.22 CEP15956.1 - 9.3e-186 617.2 13.0 1.1e-185 617.0 13.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NIF PF03031.18 CEP15957.1 - 1.7e-49 167.6 0.6 1.7e-49 167.6 0.6 2.3 3 0 0 3 3 3 1 NLI interacting factor-like phosphatase Ubiq_cyt_C_chap PF03981.12 CEP15957.1 - 6.6e-34 117.0 0.1 1.1e-33 116.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF3439 PF11921.8 CEP15957.1 - 5 7.1 25.2 0.3 11.1 13.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CEP15957.1 - 6.1 4.9 29.5 0.16 10.1 17.6 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 NT-C2 PF10358.9 CEP15958.1 - 3.4e-11 43.1 0.3 8.1e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L37e PF01907.19 CEP15959.1 - 5.7e-27 93.6 12.7 1.1e-26 92.7 12.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CEP15959.1 - 0.01 15.8 1.8 0.016 15.2 1.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 CEP15959.1 - 0.017 15.1 0.9 0.025 14.6 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 CEP15959.1 - 0.24 11.3 4.2 0.46 10.4 4.2 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DNA_RNApol_7kD PF03604.13 CEP15959.1 - 0.28 10.9 4.6 1.1 9.0 0.9 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Cnd1 PF12717.7 CEP15960.1 - 0.0082 16.2 0.4 0.55 10.3 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP15960.1 - 0.12 12.7 0.0 11 6.6 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Xpo1 PF08389.12 CEP15960.1 - 0.25 11.4 3.8 2.3 8.2 0.0 3.6 3 1 1 4 4 4 0 Exportin 1-like protein Profilin PF00235.19 CEP15962.1 - 5.7e-41 139.7 0.3 7.3e-41 139.4 0.3 1.1 1 0 0 1 1 1 1 Profilin Endonuclease_7 PF02945.15 CEP15962.1 - 0.052 13.5 0.1 3.6 7.6 0.0 2.2 1 1 1 2 2 2 0 Recombination endonuclease VII DEAD PF00270.29 CEP15963.1 - 1.4e-49 168.2 0.0 1.3e-48 165.1 0.0 2.5 3 1 1 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP15963.1 - 2.6e-23 82.5 0.2 1.2e-22 80.3 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CEP15963.1 - 1.8e-20 73.0 3.5 1.8e-20 73.0 3.5 3.0 3 0 0 3 3 3 1 DBP10CT (NUC160) domain RabGAP-TBC PF00566.18 CEP15964.1 - 6.5e-57 192.6 0.1 6.5e-57 192.6 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GAS PF13851.6 CEP15964.1 - 0.00022 20.7 22.7 0.00052 19.4 22.7 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CEP15964.1 - 0.0015 18.5 15.9 0.0015 18.5 15.9 4.3 3 1 0 4 4 4 1 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 CEP15964.1 - 0.095 12.7 12.4 0.039 14.0 8.5 2.3 1 1 1 2 2 2 0 Laminin Domain II BLOC1_2 PF10046.9 CEP15964.1 - 0.12 12.7 15.4 0.031 14.6 10.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mce4_CUP1 PF11887.8 CEP15964.1 - 0.15 11.5 2.0 0.29 10.6 2.0 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Leu_zip PF15294.6 CEP15964.1 - 0.2 11.1 19.4 0.93 8.9 19.4 2.1 1 1 0 1 1 1 0 Leucine zipper DUF4472 PF14739.6 CEP15964.1 - 0.36 11.6 19.9 0.25 12.1 13.2 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) ZapB PF06005.12 CEP15964.1 - 0.89 10.0 26.8 0.29 11.6 15.5 3.1 2 1 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 CEP15964.1 - 1.2 9.7 27.6 0.095 13.2 17.0 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region CdvA PF18822.1 CEP15964.1 - 1.3 8.9 17.7 0.17 11.7 2.6 3.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 CEP15964.1 - 1.7 9.1 11.5 5.3 7.5 0.7 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 CEP15964.1 - 2 8.6 26.4 6 7.0 0.8 2.8 1 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 CEP15964.1 - 2 8.4 10.7 0.52 10.4 7.3 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CEP15964.1 - 2.2 6.1 8.0 3.8 5.3 8.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 CEP15964.1 - 2.9 8.2 6.7 5.4 7.3 6.0 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GIT_CC PF16559.5 CEP15964.1 - 2.9 7.8 19.8 0.12 12.2 5.7 4.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Exonuc_VII_L PF02601.15 CEP15964.1 - 3.4 7.1 8.2 7.7 6.0 8.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CEP15964.1 - 3.8 6.3 17.4 0.061 12.2 7.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 CEP15964.1 - 4 7.4 24.5 1 9.4 18.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 She9_MDM33 PF05546.11 CEP15964.1 - 6.1 6.6 10.2 1.6 8.5 4.8 2.2 1 1 1 2 2 2 0 She9 / Mdm33 family AA_kinase PF00696.28 CEP15965.1 - 5.1e-42 144.1 0.8 1.1e-41 143.1 0.9 1.5 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 CEP15965.1 - 1.5e-14 53.7 0.0 5.2e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 PUA domain PTAC PF06130.12 CEP15965.1 - 0.16 12.2 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 Phosphate propanoyltransferase AAA PF00004.29 CEP15966.1 - 6e-44 149.7 0.0 1.6e-43 148.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP15966.1 - 1.2e-12 47.4 0.1 3.4e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CEP15966.1 - 1.4e-08 34.5 0.7 3.5e-08 33.3 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CEP15966.1 - 3.1e-07 30.7 0.0 6.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CEP15966.1 - 1.2e-06 28.6 0.1 6.4e-06 26.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP15966.1 - 1.6e-06 28.6 0.1 5.9e-05 23.5 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CEP15966.1 - 1.5e-05 25.3 0.1 0.0082 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CEP15966.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CEP15966.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CEP15966.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEP15966.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CEP15966.1 - 0.0035 17.9 0.1 0.02 15.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 CEP15966.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CEP15966.1 - 0.0064 15.9 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CEP15966.1 - 0.0095 15.4 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 CEP15966.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEP15966.1 - 0.011 15.1 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 CEP15966.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CEP15966.1 - 0.021 14.6 0.0 0.1 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 CEP15966.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CEP15966.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CEP15966.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP15966.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CEP15966.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RILP PF11461.8 CEP15966.1 - 0.039 14.2 1.2 0.089 13.0 1.2 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_25 PF13481.6 CEP15966.1 - 0.05 13.2 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CEP15966.1 - 0.055 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CEP15966.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 CEP15966.1 - 0.09 12.5 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEP15966.1 - 0.12 12.7 0.0 0.44 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.19 CEP15967.1 - 2.2e-06 28.0 2.7 3.9e-06 27.2 1.4 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.12 CEP15967.1 - 0.91 9.2 6.8 0.42 10.3 2.3 2.0 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.9 CEP15967.1 - 1.1 9.5 8.3 2.8 8.1 1.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 CEP15967.1 - 1.9 8.5 7.3 0.79 9.6 1.0 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bystin PF05291.11 CEP15968.1 - 4.3e-140 466.0 0.2 4.3e-140 466.0 0.2 1.6 2 0 0 2 2 2 1 Bystin FAM150 PF15129.6 CEP15968.1 - 1.7 8.8 4.4 10 6.3 1.9 2.6 2 0 0 2 2 2 0 FAM150 family Pkinase PF00069.25 CEP15969.1 - 2.3e-53 181.3 0.1 4.3e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15969.1 - 2.5e-40 138.4 0.0 4.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CEP15969.1 - 4.4e-05 23.6 0.2 0.00011 22.4 0.2 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kinase-like PF14531.6 CEP15969.1 - 0.012 14.9 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Laminin_II PF06009.12 CEP15969.1 - 0.08 13.0 2.1 0.11 12.5 0.5 2.0 2 1 0 2 2 2 0 Laminin Domain II Phlebovirus_NSM PF07246.11 CEP15969.1 - 0.088 12.2 2.4 0.16 11.3 2.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Uds1 PF15456.6 CEP15969.1 - 2.2 8.4 9.4 6.5 6.9 5.0 2.5 1 1 1 2 2 2 0 Up-regulated During Septation Snf7 PF03357.21 CEP15970.1 - 2e-16 60.1 12.6 4.1e-16 59.1 12.6 1.6 1 0 0 1 1 1 1 Snf7 DUF4611 PF15387.6 CEP15970.1 - 0.12 12.6 0.9 0.45 10.8 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Haem_degrading PF03928.14 CEP15971.1 - 6.7e-33 113.3 0.0 8.5e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Solute_trans_a PF03619.16 CEP15972.1 - 3.2e-09 36.7 0.7 5.1e-09 36.0 0.7 1.4 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ABC_membrane PF00664.23 CEP15973.1 - 3.9e-50 171.0 27.8 1.6e-29 103.4 5.9 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP15973.1 - 2.5e-43 147.9 0.0 4.7e-27 95.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP15973.1 - 2.3e-08 33.7 0.3 0.01 15.3 2.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CEP15973.1 - 4.8e-05 22.6 0.0 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 CEP15973.1 - 0.0004 20.1 1.5 0.2 11.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP15973.1 - 0.0015 18.9 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CEP15973.1 - 0.0019 17.8 0.1 0.89 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CEP15973.1 - 0.0023 18.5 0.6 2.9 8.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CEP15973.1 - 0.0046 17.0 0.1 0.64 10.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CEP15973.1 - 0.0062 15.9 0.3 0.9 8.8 0.0 2.3 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 CEP15973.1 - 0.0075 15.5 0.0 0.19 10.9 0.0 3.2 4 1 0 4 4 4 1 NB-ARC domain TrwB_AAD_bind PF10412.9 CEP15973.1 - 0.0098 14.8 0.5 3.5 6.4 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 CEP15973.1 - 0.011 16.0 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CEP15973.1 - 0.015 15.0 1.9 0.063 13.0 0.2 2.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CEP15973.1 - 0.043 13.2 0.1 7.9 5.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 CEP15973.1 - 0.088 12.9 4.1 0.17 12.0 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 CEP15973.1 - 0.14 12.1 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 CEP15973.1 - 0.22 10.9 0.9 21 4.4 0.2 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_21 PF13304.6 CEP15973.1 - 0.27 11.0 2.3 18 5.0 0.8 2.9 2 1 1 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 CEP15973.1 - 0.71 9.0 3.1 2.7 7.1 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Fungal_trans PF04082.18 CEP15974.1 - 7.2e-42 143.2 0.1 1.2e-41 142.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Neurensin PF14927.6 CEP15975.1 - 0.026 14.2 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 Neurensin GRIM-19 PF06212.12 CEP15976.1 - 1.1e-29 103.1 0.1 1.2e-29 102.9 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein zf-RVT PF13966.6 CEP15977.1 - 3.5e-08 34.0 0.4 6.3e-08 33.2 0.4 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Polysacc_lyase PF14099.6 CEP15978.1 - 7.3e-05 22.7 0.1 0.00017 21.5 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide lyase bZIP_2 PF07716.15 CEP15979.1 - 1.2e-07 31.7 7.7 2.9e-07 30.5 7.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP15979.1 - 1.2e-06 28.6 7.4 2.4e-06 27.5 7.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor CDC27 PF09507.10 CEP15979.1 - 0.0014 18.1 4.4 0.0021 17.5 4.4 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 HALZ PF02183.18 CEP15979.1 - 0.031 14.5 0.8 0.45 10.8 0.4 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 CEP15979.1 - 0.094 13.2 2.9 0.2 12.1 2.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB FAM176 PF14851.6 CEP15979.1 - 0.18 11.5 3.5 0.34 10.6 3.5 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CEP15979.1 - 0.27 10.5 7.5 0.42 9.9 7.5 1.3 1 0 0 1 1 1 0 NOA36 protein Spc42p PF11544.8 CEP15979.1 - 1.1 9.3 6.9 0.18 11.8 2.9 1.9 2 0 0 2 2 2 0 Spindle pole body component Spc42p Tom22 PF04281.13 CEP15979.1 - 1.4 8.7 7.9 0.55 10.0 4.8 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 KIAA1430 PF13879.6 CEP15979.1 - 3.6 8.4 9.2 15 6.4 7.4 2.8 1 1 1 2 2 2 0 KIAA1430 homologue DUF4611 PF15387.6 CEP15979.1 - 4 7.7 10.0 0.19 12.0 4.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 CEP15979.1 - 5.2 7.5 13.8 0.82 10.1 9.1 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_hydro_45 PF02015.16 CEP15980.1 - 6.6e-81 271.2 19.8 6.6e-81 271.2 19.8 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 CEP15980.1 - 1.3e-18 66.6 33.1 9.6e-11 41.5 12.3 3.6 3 0 0 3 3 3 2 Fungal cellulose binding domain RIFIN PF02009.16 CEP15980.1 - 0.2 11.5 5.5 0.24 11.3 5.5 1.2 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 CEP15980.1 - 6.5 3.7 7.3 7.6 3.5 7.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Catalase PF00199.19 CEP15981.1 - 1.9e-163 544.1 0.0 2.8e-163 543.5 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 CEP15981.1 - 8.4e-32 109.9 0.0 1.4e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 CEP15981.1 - 4.5e-17 62.0 0.1 1e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Phage_TAC_1 PF06222.11 CEP15981.1 - 0.16 11.8 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Sec23_trunk PF04811.15 CEP15982.1 - 1.8e-61 207.8 0.1 3.1e-61 207.0 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEP15982.1 - 7.9e-22 77.0 0.0 1.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CEP15982.1 - 1.2e-15 58.0 0.1 3.7e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CEP15982.1 - 8e-15 54.6 6.7 1.5e-14 53.7 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEP15982.1 - 5.3e-10 39.1 0.0 2.2e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat DUF5399 PF17377.2 CEP15983.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5399) zf-C2H2_4 PF13894.6 CEP15983.1 - 0.23 12.4 0.1 0.23 12.4 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP15983.1 - 1 10.0 0.1 1 10.0 0.1 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CEP15983.1 - 4 7.8 7.6 1.5 9.2 1.3 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) YpjP PF14005.6 CEP15984.1 - 0.11 12.5 0.0 0.11 12.5 0.0 3.6 3 1 0 3 3 3 0 YpjP-like protein MazG PF03819.17 CEP15985.1 - 0.022 15.0 0.5 0.022 15.0 0.5 2.3 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain POTRA_TamA_1 PF17243.2 CEP15985.1 - 0.21 11.7 2.9 0.62 10.2 0.7 2.5 1 1 1 2 2 2 0 POTRA domain TamA domain 1 AAA_lid_1 PF17857.1 CEP15985.1 - 0.26 11.5 3.1 0.28 11.4 1.6 1.8 1 1 0 1 1 1 0 AAA+ lid domain KMP11 PF03037.16 CEP15985.1 - 0.31 11.8 12.2 2.3 9.1 6.7 2.4 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Exonuc_VII_L PF02601.15 CEP15985.1 - 0.63 9.6 6.6 0.81 9.2 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mit_ribos_Mrp51 PF11709.8 CEP15985.1 - 1.1 8.8 6.2 1.4 8.4 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF848 PF05852.11 CEP15985.1 - 1.5 8.9 11.8 0.73 9.9 8.7 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) GvpL_GvpF PF06386.11 CEP15985.1 - 2.6 7.9 12.2 0.45 10.4 6.9 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF2229 PF09989.9 CEP15985.1 - 3.5 7.2 6.7 4.9 6.8 6.5 1.4 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) LMBR1 PF04791.16 CEP15985.1 - 4 6.2 8.7 4.7 6.0 8.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CRR7 PF12095.8 CEP15985.1 - 6.6 7.3 15.4 7 7.2 1.6 2.9 1 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Peptidase_S8 PF00082.22 CEP15986.1 - 8.8e-52 176.2 0.4 1.6e-51 175.3 0.4 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 CEP15986.1 - 9.8e-13 48.0 0.0 3.3e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 CEP15986.1 - 3e-07 31.1 0.0 6.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Hexapep PF00132.24 CEP15987.1 - 7e-10 38.2 17.9 6.8e-07 28.8 3.1 4.6 3 2 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CEP15987.1 - 1.8e-05 23.9 0.5 3.7e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 L-fucokinase Hexapep_2 PF14602.6 CEP15987.1 - 0.00022 20.9 13.7 0.00028 20.6 1.3 3.5 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 CEP15988.1 - 3.2e-56 190.6 0.0 4.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15988.1 - 9.3e-28 97.2 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CEP15988.1 - 0.00018 21.2 0.1 0.0045 16.6 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP15988.1 - 0.00082 19.4 0.1 0.8 9.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CEP15988.1 - 0.0039 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CEP15988.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Macoilin PF09726.9 CEP15988.1 - 0.71 8.4 6.1 0.83 8.1 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 CEP15988.1 - 3.6 5.5 9.8 4.9 5.0 9.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_phi PF04931.13 CEP15988.1 - 9 4.3 8.5 12 3.8 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_7 PF13499.6 CEP15989.1 - 1.2e-05 25.6 0.0 3.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair F-box PF00646.33 CEP15989.1 - 1.6e-05 24.6 0.0 8.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain EF-hand_6 PF13405.6 CEP15989.1 - 7.4e-05 22.4 0.1 0.00036 20.2 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEP15989.1 - 0.00035 19.9 0.8 0.00093 18.6 0.8 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CEP15989.1 - 0.00059 19.2 1.8 0.0016 17.9 1.8 1.8 1 0 0 1 1 1 1 EF hand EF_assoc_1 PF08355.12 CEP15989.1 - 0.00096 18.7 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 EF hand associated ANAPC3 PF12895.7 CEP15989.1 - 0.0026 18.0 0.1 0.0074 16.5 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CEP15989.1 - 0.004 17.8 0.0 0.013 16.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.7 CEP15989.1 - 0.0082 16.0 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 CEP15989.1 - 0.013 15.6 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP15989.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PWI PF01480.17 CEP15990.1 - 2.6e-14 53.3 0.2 6.1e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 CEP15990.1 - 3.8e-08 33.0 0.0 1.1e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UL40 PF10682.9 CEP15990.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Pkinase PF00069.25 CEP15991.1 - 5.4e-61 206.3 0.0 6.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15991.1 - 8e-23 81.0 0.0 1.4e-22 80.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP15991.1 - 2.1e-07 30.6 0.0 1.1e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CEP15991.1 - 0.0027 17.7 0.0 0.04 13.8 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CEP15991.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nore1-SARAH PF16517.5 CEP15992.1 - 0.00099 19.0 2.3 0.008 16.1 2.3 2.7 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain NPV_P10 PF05531.12 CEP15992.1 - 1.3 9.6 16.2 8.2 7.0 0.1 5.5 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein SATase_N PF06426.14 CEP15992.1 - 2 8.8 4.9 15 6.0 0.0 3.8 4 0 0 4 4 4 0 Serine acetyltransferase, N-terminal F-box-like PF12937.7 CEP15993.1 - 6.8e-07 29.1 0.3 1.8e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like mTERF PF02536.14 CEP15993.1 - 0.0012 17.9 0.2 0.0021 17.1 0.2 1.3 1 0 0 1 1 1 1 mTERF F-box PF00646.33 CEP15993.1 - 0.036 14.0 0.1 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 F-box domain XRN_N PF03159.18 CEP15993.1 - 0.085 12.3 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus MukE PF04288.13 CEP15995.1 - 0.01 14.8 0.6 0.016 14.1 0.6 1.3 1 0 0 1 1 1 0 MukE-like family Pkinase PF00069.25 CEP15997.1 - 2.7e-53 181.1 0.0 4.3e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP15997.1 - 8.7e-20 71.1 0.1 1.7e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP15997.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 CEP15997.1 - 0.043 13.4 1.6 0.078 12.6 1.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Zn_clus PF00172.18 CEP15998.1 - 3.6e-16 59.0 28.9 4.9e-08 33.0 10.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CEP15999.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.18 CEP16000.1 - 1.6e-31 108.2 0.0 3.4e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain CotH PF08757.11 CEP16002.1 - 1.8e-36 126.3 1.1 2.6e-36 125.8 1.1 1.2 1 0 0 1 1 1 1 CotH kinase protein Isochorismatase PF00857.20 CEP16003.1 - 1e-19 71.4 0.0 2.4e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Tetraspanin PF00335.20 CEP16004.1 - 0.0045 16.7 19.8 0.017 14.8 19.8 1.8 1 1 0 1 1 1 1 Tetraspanin family WD40 PF00400.32 CEP16005.1 - 4.1e-25 87.6 20.2 0.00024 21.8 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16005.1 - 2.9e-06 27.5 0.4 0.027 14.7 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CEP16005.1 - 0.00037 20.9 2.8 22 5.7 0.0 5.2 6 1 0 6 6 6 2 PQQ-like domain Nup160 PF11715.8 CEP16005.1 - 0.011 14.4 8.6 1.5 7.4 0.1 4.5 1 1 3 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP16005.1 - 0.056 12.8 0.3 3.3 6.9 0.0 2.4 1 1 0 2 2 2 0 WD40-like domain Acetyltransf_10 PF13673.7 CEP16006.1 - 6.8e-09 35.7 0.0 9.7e-09 35.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP16006.1 - 3.6e-07 30.5 0.0 5.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP16006.1 - 6.3e-06 26.4 0.0 8.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CEP16006.1 - 0.019 15.1 0.0 0.061 13.4 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP16006.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CEP16006.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase EF-hand_4 PF12763.7 CEP16007.1 - 0.035 14.1 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand UL42 PF17638.2 CEP16007.1 - 3.4 7.6 7.4 0.77 9.7 2.8 2.2 2 0 0 2 2 2 0 HCMV UL42 Tim17 PF02466.19 CEP16008.1 - 7.7e-08 32.7 0.4 2.2e-07 31.2 0.2 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 CEP16008.1 - 2.3e-07 31.5 1.0 0.0013 19.4 0.1 3.4 2 2 1 3 3 3 2 N-terminal cysteine-rich region of Transmembrane protein 135 IBV_3C PF03620.13 CEP16008.1 - 0.077 13.5 0.9 23 5.6 0.2 2.6 2 0 0 2 2 2 0 IBV 3C protein DTHCT PF08070.11 CEP16009.1 - 0.0076 17.0 4.0 0.0076 17.0 4.0 3.7 2 1 1 3 3 3 1 DTHCT (NUC029) region Spt20 PF12090.8 CEP16009.1 - 4.2 6.9 27.0 0.14 11.7 14.7 2.3 2 0 0 2 2 2 0 Spt20 family Band_3_cyto PF07565.13 CEP16009.1 - 8.8 6.0 13.2 1.1 9.0 4.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain HEAT PF02985.22 CEP16010.1 - 0.00043 20.3 0.1 0.74 10.2 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat UVR PF02151.19 CEP16010.1 - 0.00053 19.6 0.7 0.00053 19.6 0.7 2.4 2 0 0 2 2 2 1 UvrB/uvrC motif TRAF6_Z2 PF18048.1 CEP16010.1 - 0.012 15.6 0.1 0.012 15.6 0.1 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 HEAT_2 PF13646.6 CEP16010.1 - 0.016 15.5 0.9 0.43 11.0 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 CEP16010.1 - 0.11 13.1 0.6 0.77 10.4 0.1 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region zf_UBZ PF18439.1 CEP16010.1 - 0.24 11.0 3.5 0.53 9.9 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PPR_2 PF13041.6 CEP16011.1 - 1.4e-58 194.9 21.0 5e-11 42.6 0.1 10.4 7 3 4 11 11 11 10 PPR repeat family PPR_3 PF13812.6 CEP16011.1 - 7.3e-34 115.7 11.9 6.7e-12 45.3 0.1 8.3 6 2 3 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 CEP16011.1 - 1.3e-32 109.7 31.4 1.6e-05 24.8 0.0 12.0 13 0 0 13 13 13 7 PPR repeat PPR_1 PF12854.7 CEP16011.1 - 1e-20 73.1 16.2 1e-07 31.5 0.0 9.9 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 CEP16011.1 - 1e-20 74.0 4.8 5.3e-13 48.8 0.2 4.1 3 1 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 CEP16011.1 - 0.0014 19.0 2.1 16 5.9 0.0 4.8 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 CEP16011.1 - 0.0044 17.7 0.8 80 4.5 0.1 4.8 6 1 1 7 7 4 0 Tetratricopeptide repeat BTAD PF03704.17 CEP16011.1 - 0.0068 16.8 1.4 11 6.5 0.1 4.2 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 CEP16011.1 - 0.01 15.0 0.1 0.59 9.3 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEP16011.1 - 0.012 16.1 0.3 17 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MNE1 PF13762.6 CEP16011.1 - 0.57 10.2 4.7 1.1e+02 2.7 0.1 4.3 3 2 2 5 5 5 0 Mitochondrial splicing apparatus component Brix PF04427.18 CEP16012.1 - 3e-44 151.4 0.2 4.7e-44 150.8 0.2 1.3 1 0 0 1 1 1 1 Brix domain IDH PF03971.14 CEP16013.1 - 0.092 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Fungal_trans PF04082.18 CEP16014.1 - 5.5e-20 71.5 3.6 9.7e-20 70.7 3.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP16014.1 - 0.45 10.7 10.7 0.94 9.7 10.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WRKY PF03106.15 CEP16015.1 - 7.2e-11 42.2 1.4 1.4e-10 41.2 1.4 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.16 CEP16015.1 - 0.029 14.5 0.3 0.062 13.4 0.3 1.6 1 0 0 1 1 1 0 FLYWCH zinc finger domain Ribosomal_L13e PF01294.18 CEP16016.1 - 5.9e-79 264.1 4.2 8.8e-79 263.5 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e G_glu_transpept PF01019.21 CEP16017.1 - 1.2e-133 446.6 0.0 1.3e-133 446.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase BET PF17035.5 CEP16018.1 - 0.00065 19.8 0.5 0.00065 19.8 0.5 2.5 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Gly_transf_sug PF04488.15 CEP16021.1 - 1.1e-09 38.8 0.0 4.4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Laminin_G_3 PF13385.6 CEP16021.1 - 4.7e-07 30.1 0.7 1e-06 29.0 0.7 1.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TcdA_TcdB PF12919.7 CEP16021.1 - 6.4e-05 22.4 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 CEP16021.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_hydro_125 PF06824.11 CEP16022.1 - 2.1e-151 504.5 0.0 2.4e-151 504.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MFS_1 PF07690.16 CEP16023.1 - 1.9e-32 112.6 21.6 5.3e-30 104.5 24.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CEP16023.1 - 3.5e-05 23.3 1.1 3.5e-05 23.3 1.1 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB p12I PF12233.8 CEP16023.1 - 3.5 8.2 9.5 0.58 10.7 0.3 3.4 3 1 1 4 4 4 0 Human adult T cell leukemia/lymphoma virus protein Porin_3 PF01459.22 CEP16024.1 - 1e-60 205.5 0.3 1.2e-60 205.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tubulin PF00091.25 CEP16025.1 - 1.2e-68 231.2 0.0 1.7e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP16025.1 - 4.2e-49 165.9 0.0 6.8e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CEP16025.1 - 0.00046 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Motile_Sperm PF00635.26 CEP16026.1 - 5.7e-26 90.5 0.7 1.2e-25 89.5 0.2 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain Atrophin-1 PF03154.15 CEP16026.1 - 0.0014 17.1 15.9 0.0016 16.9 15.9 1.1 1 0 0 1 1 1 1 Atrophin-1 family Ge1_WD40 PF16529.5 CEP16027.1 - 0.032 13.2 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cas_Csx8 PF09657.10 CEP16027.1 - 0.072 12.1 0.1 0.072 12.1 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) MBOAT PF03062.19 CEP16029.1 - 1.8e-45 155.8 9.2 3e-45 155.1 9.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1516 PF07457.11 CEP16029.1 - 0.77 10.0 4.9 0.38 11.0 0.9 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1516) PQQ_2 PF13360.6 CEP16030.1 - 1.7e-13 50.7 0.3 5.8e-06 26.1 0.1 2.8 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 CEP16030.1 - 1.9e-12 46.5 5.9 0.0011 18.8 0.0 4.4 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 CEP16030.1 - 1.8e-10 41.0 3.6 0.0085 16.6 0.0 5.4 5 0 0 5 5 5 2 PQQ-like domain SUKH_5 PF14567.6 CEP16030.1 - 0.063 13.0 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall SH3_1 PF00018.28 CEP16031.1 - 8.9e-12 44.4 0.1 8.9e-12 44.4 0.1 1.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CEP16031.1 - 2.3e-09 36.8 0.0 5.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP16031.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 CEP16031.1 - 0.098 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain DUF2070 PF09843.9 CEP16031.1 - 8.3 4.6 8.9 11 4.1 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mito_carr PF00153.27 CEP16032.1 - 4.1e-76 251.0 0.5 4.8e-25 87.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP16032.1 - 1.4e-05 24.4 0.2 0.3 10.2 0.0 4.0 3 1 2 5 5 5 2 Gammaproteobacterial serine protease EF-hand_6 PF13405.6 CEP16032.1 - 4.2e-05 23.1 1.1 0.00045 19.9 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CEP16032.1 - 7.2e-05 22.1 0.1 0.0014 18.1 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CEP16032.1 - 8.6e-05 22.9 0.3 0.00018 21.9 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CEP16032.1 - 0.0042 16.5 0.3 0.0084 15.6 0.3 1.5 1 0 0 1 1 1 1 EF hand WD40 PF00400.32 CEP16033.1 - 2.5e-15 56.6 9.6 2.2e-05 25.1 0.0 5.9 6 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16033.1 - 1.9e-07 31.3 0.0 0.063 13.6 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP16033.1 - 0.095 12.6 0.2 1.4 8.7 0.0 2.6 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A rve PF00665.26 CEP16034.1 - 3e-14 53.2 0.0 5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP16034.1 - 0.00044 20.0 0.0 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain UBN_AB PF14075.6 CEP16035.1 - 0.043 13.5 0.2 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PapB PF03333.13 CEP16035.1 - 0.057 13.5 0.4 0.32 11.0 0.0 2.3 3 0 0 3 3 3 0 Adhesin biosynthesis transcription regulatory protein DUF35_N PF12172.8 CEP16035.1 - 0.2 11.6 1.3 0.39 10.6 1.3 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RT_RNaseH_2 PF17919.1 CEP16036.1 - 4e-18 65.3 2.0 5.7e-16 58.4 0.2 3.4 3 1 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16036.1 - 3.1e-17 62.8 0.2 1.2e-16 60.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP16036.1 - 1.4e-06 28.3 0.0 3.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain SET PF00856.28 CEP16037.1 - 4.1e-12 46.8 0.3 3.6e-11 43.7 0.0 2.4 2 1 0 2 2 2 1 SET domain BBIP10 PF14777.6 CEP16037.1 - 0.36 10.4 6.2 2.2 7.9 0.2 2.5 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Pan3_PK PF18101.1 CEP16038.1 - 4.9e-66 220.9 0.1 4.9e-66 220.9 0.1 1.9 2 0 0 2 2 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CEP16038.1 - 0.0027 17.1 4.2 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain TERB2 PF15101.6 CEP16038.1 - 0.0049 16.9 10.6 0.01 15.9 10.6 1.5 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Spem1 PF15670.5 CEP16038.1 - 0.012 15.3 9.6 0.024 14.2 9.6 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 EPL1 PF10513.9 CEP16038.1 - 0.012 16.0 7.7 0.029 14.7 7.7 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like PAM2 PF07145.15 CEP16038.1 - 0.017 14.8 1.5 0.039 13.7 1.5 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TFIIA PF03153.13 CEP16038.1 - 0.025 14.6 37.2 0.05 13.6 37.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 CEP16038.1 - 0.031 13.7 7.4 0.052 13.0 7.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CEP16038.1 - 0.065 12.0 10.3 0.09 11.5 10.3 1.2 1 0 0 1 1 1 0 Presenilin Rsc14 PF08586.10 CEP16038.1 - 0.14 13.0 3.5 0.67 10.8 3.1 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Neur_chan_memb PF02932.16 CEP16038.1 - 0.16 12.0 5.5 0.26 11.3 5.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4770 PF15994.5 CEP16038.1 - 0.22 11.8 14.5 0.47 10.7 14.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Rrn6 PF10214.9 CEP16038.1 - 0.28 9.6 19.9 0.38 9.2 19.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tim54 PF11711.8 CEP16038.1 - 0.29 9.9 6.9 0.54 9.0 6.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5308 PF17233.2 CEP16038.1 - 0.47 10.7 10.3 0.48 10.6 7.9 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5308) Baculo_PP31 PF05311.11 CEP16038.1 - 0.48 9.9 10.3 0.85 9.1 10.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SLC12 PF03522.15 CEP16038.1 - 0.51 9.3 8.9 0.78 8.7 8.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CEP16038.1 - 0.65 9.8 9.6 1 9.1 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 CEP16038.1 - 1.1 8.3 6.6 1.7 7.6 6.6 1.2 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 CEP16038.1 - 2.1 8.1 7.0 4.1 7.1 7.0 1.4 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 CEP16038.1 - 2.4 7.0 17.7 3.9 6.4 17.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CEP16038.1 - 2.9 8.1 10.3 0.48 10.6 6.1 1.8 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 CEP16038.1 - 2.9 7.6 9.3 5.5 6.7 9.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.9 CEP16038.1 - 3.5 5.8 31.9 5.1 5.3 31.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.8 CEP16038.1 - 3.7 6.6 23.5 6.3 5.8 23.5 1.3 1 0 0 1 1 1 0 SprA-related family Lin-8 PF03353.15 CEP16038.1 - 4.2 6.8 18.2 0.77 9.3 14.1 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CEP16038.1 - 6 4.9 12.7 8.1 4.4 12.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PepSY_TM PF03929.16 CEP16038.1 - 6.5 6.3 5.8 12 5.4 5.8 1.4 1 0 0 1 1 1 0 PepSY-associated TM region PBP_sp32 PF07222.12 CEP16038.1 - 6.6 6.1 18.1 11 5.4 18.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec62 PF03839.16 CEP16038.1 - 9.5 5.7 8.0 16 4.9 8.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4175 PF13779.6 CEP16038.1 - 9.7 3.9 33.1 13 3.5 33.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RT_RNaseH_2 PF17919.1 CEP16041.1 - 8.8e-28 96.3 0.0 1.6e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16041.1 - 2e-21 76.2 0.0 4.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP16041.1 - 2.1e-07 30.9 0.1 4.7e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Pinin_SDK_N PF04697.13 CEP16041.1 - 0.073 13.7 0.7 0.16 12.6 0.4 1.7 2 0 0 2 2 2 0 pinin/SDK conserved region zf-H2C2 PF09337.10 CEP16041.1 - 0.21 11.9 0.3 0.58 10.4 0.3 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Transposase_21 PF02992.14 CEP16043.1 - 0.00074 18.8 0.1 0.0041 16.4 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 GAGA PF09237.11 CEP16044.1 - 0.046 13.5 2.3 0.067 13.0 2.3 1.3 1 0 0 1 1 1 0 GAGA factor Herpes_U59 PF04529.12 CEP16045.1 - 0.052 12.6 0.1 0.058 12.4 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus U59 protein CCM2_C PF16545.5 CEP16045.1 - 0.14 12.7 0.1 0.19 12.3 0.1 1.2 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology DUF603 PF04645.12 CEP16045.1 - 0.15 11.8 0.1 0.19 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF4218 PF13960.6 CEP16046.1 - 0.002 17.7 0.1 0.0024 17.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1258 PF06869.12 CEP16047.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) RVT_1 PF00078.27 CEP16048.1 - 1.6e-18 67.0 0.0 2.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP16048.1 - 9.9e-17 60.8 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16048.1 - 9.3e-05 22.7 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP16050.1 - 4.4e-07 29.6 0.0 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tropomyosin_1 PF12718.7 CEP16051.1 - 7e-31 107.3 39.5 7e-31 107.3 39.5 1.4 1 1 1 2 2 2 1 Tropomyosin like PspA_IM30 PF04012.12 CEP16051.1 - 6.5e-06 25.9 30.0 1e-05 25.3 28.6 1.8 1 1 1 2 2 2 1 PspA/IM30 family CENP-F_leu_zip PF10473.9 CEP16051.1 - 7.6e-06 26.0 39.0 0.00036 20.6 12.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 CEP16051.1 - 8.7e-06 25.3 37.6 1.8e-05 24.2 37.6 1.6 1 1 0 1 1 1 1 Tropomyosin Laminin_II PF06009.12 CEP16051.1 - 2.2e-05 24.5 26.6 0.00049 20.1 12.4 2.4 1 1 1 2 2 2 2 Laminin Domain II MscS_porin PF12795.7 CEP16051.1 - 3.9e-05 23.3 34.3 8.6e-05 22.2 27.0 2.0 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 CEP16051.1 - 5.8e-05 22.8 37.1 0.0001 22.1 37.1 1.4 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 CEP16051.1 - 0.00017 21.9 37.6 0.036 14.3 9.5 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DHR10 PF18595.1 CEP16051.1 - 0.0003 20.8 39.6 0.012 15.6 14.1 2.7 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain ADIP PF11559.8 CEP16051.1 - 0.00057 20.0 36.4 0.014 15.5 9.7 3.0 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 CEP16051.1 - 0.00077 19.5 37.0 0.026 14.6 14.0 2.1 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase Lectin_N PF03954.14 CEP16051.1 - 0.0012 18.6 8.4 0.0012 18.6 8.4 2.9 1 1 2 3 3 3 1 Hepatic lectin, N-terminal domain TolA_bind_tri PF16331.5 CEP16051.1 - 0.0017 18.4 9.5 0.0017 18.4 9.5 3.1 1 1 2 3 3 3 1 TolA binding protein trimerisation HrpB7 PF09486.10 CEP16051.1 - 0.0018 18.7 19.8 0.13 12.6 4.2 2.6 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 CEP16051.1 - 0.0019 17.2 38.2 0.1 11.5 10.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Rootletin PF15035.6 CEP16051.1 - 0.003 17.6 33.3 0.0085 16.1 16.4 2.9 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 CEP16051.1 - 0.0033 17.4 47.4 0.041 13.9 11.0 3.6 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding TRAF_BIRC3_bd PF16673.5 CEP16051.1 - 0.0043 16.8 3.1 0.0043 16.8 3.1 3.2 2 2 1 3 3 3 1 TNF receptor-associated factor BIRC3 binding domain EzrA PF06160.12 CEP16051.1 - 0.0047 15.2 32.8 0.059 11.6 9.3 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Cep57_CLD_2 PF14197.6 CEP16051.1 - 0.0061 16.6 36.1 0.15 12.1 5.8 3.2 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 Fez1 PF06818.15 CEP16051.1 - 0.0065 16.9 31.1 0.0093 16.4 30.5 1.6 1 1 0 1 1 1 1 Fez1 GAS PF13851.6 CEP16051.1 - 0.007 15.7 37.7 0.024 14.0 37.7 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 CEP16051.1 - 0.0078 14.9 30.6 0.01 14.6 30.6 1.1 1 0 0 1 1 1 1 AAA domain ZapB PF06005.12 CEP16051.1 - 0.0093 16.4 45.4 0.078 13.4 5.9 3.8 1 1 1 3 3 3 2 Cell division protein ZapB HR1 PF02185.16 CEP16051.1 - 0.01 16.0 30.9 0.25 11.5 1.0 5.0 1 1 4 5 5 5 2 Hr1 repeat CENP-H PF05837.12 CEP16051.1 - 0.011 16.2 29.3 0.083 13.3 7.3 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 CEP16051.1 - 0.012 15.7 37.9 0.18 11.9 13.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 CEP16051.1 - 0.016 15.3 38.7 0.076 13.1 33.4 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 CEP16051.1 - 0.016 15.0 30.4 0.098 12.5 10.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 CEP16051.1 - 0.016 14.5 31.2 0.099 11.9 10.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CEP16051.1 - 0.017 15.7 44.0 0.34 11.5 18.8 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 CEP16051.1 - 0.022 13.6 31.2 0.08 11.8 31.2 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 CEP16051.1 - 0.023 15.3 33.2 0.29 11.7 6.8 2.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 KLRAQ PF10205.9 CEP16051.1 - 0.024 14.9 30.1 0.52 10.6 10.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF812 PF05667.11 CEP16051.1 - 0.03 13.2 35.1 0.1 11.4 35.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 CEP16051.1 - 0.034 13.9 33.1 3 7.5 15.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 CEP16051.1 - 0.035 13.2 30.1 0.083 12.0 9.5 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CEP16051.1 - 0.038 14.0 21.6 0.4 10.7 4.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 CEP16051.1 - 0.047 13.5 38.5 0.89 9.3 13.3 3.9 1 1 3 4 4 4 0 Phage minor structural protein GP20 SlyX PF04102.12 CEP16051.1 - 0.054 14.1 26.6 0.45 11.2 8.0 3.3 1 1 2 3 3 3 0 SlyX MAD PF05557.13 CEP16051.1 - 0.06 11.7 34.8 0.2 10.0 34.4 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein HOOK PF05622.12 CEP16051.1 - 0.062 11.5 37.3 0.01 14.0 20.0 2.0 1 1 1 2 2 2 0 HOOK protein FlaC_arch PF05377.11 CEP16051.1 - 0.071 13.5 30.4 0.51 10.8 4.8 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 CEP16051.1 - 0.089 12.4 30.5 1.2 8.7 8.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein Uso1_p115_C PF04871.13 CEP16051.1 - 0.095 13.1 37.4 0.16 12.4 13.0 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WXG100 PF06013.12 CEP16051.1 - 0.098 12.9 15.6 2.3 8.5 3.8 4.2 2 2 1 3 3 3 0 Proteins of 100 residues with WXG HMMR_N PF15905.5 CEP16051.1 - 0.11 11.9 36.3 0.94 8.9 33.4 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal THOC7 PF05615.13 CEP16051.1 - 0.14 12.4 30.9 0.046 14.0 6.9 2.9 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 CEP16051.1 - 0.16 11.3 24.9 0.19 11.0 24.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 CEP16051.1 - 0.16 12.6 28.4 0.96 10.1 12.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Nup54 PF13874.6 CEP16051.1 - 0.17 12.0 24.5 1.8 8.7 15.9 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF3584 PF12128.8 CEP16051.1 - 0.18 9.3 33.5 0.46 7.9 33.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FPP PF05911.11 CEP16051.1 - 0.21 9.7 36.5 0.27 9.4 9.4 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil CLZ PF16526.5 CEP16051.1 - 0.27 11.6 31.3 5.8 7.3 9.8 4.6 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4164 PF13747.6 CEP16051.1 - 0.29 11.4 28.7 0.037 14.3 7.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HemX PF04375.14 CEP16051.1 - 0.44 9.8 26.8 0.42 9.8 12.6 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase PilJ PF13675.6 CEP16051.1 - 0.46 10.5 10.8 0.4 10.7 1.4 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CtIP_N PF10482.9 CEP16051.1 - 0.48 10.5 26.5 0.23 11.5 6.8 2.9 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain KxDL PF10241.9 CEP16051.1 - 0.48 10.7 27.3 0.86 9.9 7.1 3.4 1 1 3 4 4 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 CEP16051.1 - 0.55 10.8 23.6 0.31 11.6 4.6 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal OmpH PF03938.14 CEP16051.1 - 0.57 10.5 35.6 1.7 9.0 18.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BORCS7 PF16088.5 CEP16051.1 - 0.7 10.2 12.3 0.61 10.4 8.4 2.6 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 ABC_tran_CTD PF16326.5 CEP16051.1 - 0.9 9.8 39.0 0.46 10.8 12.7 3.3 1 1 3 4 4 4 0 ABC transporter C-terminal domain IFT57 PF10498.9 CEP16051.1 - 0.99 8.3 30.2 0.84 8.5 21.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF2524 PF10732.9 CEP16051.1 - 1.1 9.6 25.4 4.9 7.5 12.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) Golgin_A5 PF09787.9 CEP16051.1 - 1.1 8.6 34.4 1.3 8.4 34.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 YscO PF07321.12 CEP16051.1 - 1.2 9.1 32.3 0.47 10.4 7.7 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO baeRF_family2 PF18844.1 CEP16051.1 - 1.3 9.1 9.3 1.1 9.4 1.6 2.3 1 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 NPV_P10 PF05531.12 CEP16051.1 - 1.3 9.5 22.4 0.99 9.9 5.3 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Phage_HK97_TLTM PF06120.11 CEP16051.1 - 1.4 8.1 26.1 1.5 8.0 12.9 2.4 1 1 1 2 2 2 0 Tail length tape measure protein TMPIT PF07851.13 CEP16051.1 - 1.5 8.0 26.5 1.1 8.4 12.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein BLOC1_2 PF10046.9 CEP16051.1 - 1.7 9.0 27.1 0.53 10.6 5.2 3.7 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CEP16051.1 - 1.7 8.8 24.0 3.5 7.8 19.3 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RPW8 PF05659.11 CEP16051.1 - 2.2 8.0 16.2 0.27 10.9 5.0 2.9 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Nup88 PF10168.9 CEP16051.1 - 2.3 5.9 24.0 2.5 5.8 24.0 1.0 1 0 0 1 1 1 0 Nuclear pore component Phage_GPO PF05929.11 CEP16051.1 - 2.4 7.7 24.6 5.6 6.5 13.0 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF16 PF01519.16 CEP16051.1 - 2.5 8.6 29.2 15 6.1 12.9 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlxA PF14282.6 CEP16051.1 - 2.7 8.0 32.7 0.67 10.0 11.9 3.4 1 1 2 3 3 3 0 FlxA-like protein KASH_CCD PF14662.6 CEP16051.1 - 2.7 7.8 38.8 1.2 8.9 28.9 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 CEP16051.1 - 3.1 7.8 36.9 0.4 10.7 12.5 4.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4200 PF13863.6 CEP16051.1 - 3.2 8.2 39.4 1.4 9.3 21.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 CEP16051.1 - 3.2 5.5 25.5 0.53 8.1 11.4 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PEARLI-4 PF05278.12 CEP16051.1 - 3.3 7.2 26.6 6.7 6.2 3.4 2.4 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DivIC PF04977.15 CEP16051.1 - 3.7 7.4 38.2 2.7 7.8 9.7 4.0 1 1 2 3 3 3 0 Septum formation initiator DUF5344 PF17279.2 CEP16051.1 - 3.9 8.1 23.9 4.2 8.0 4.6 3.1 1 1 2 3 3 3 0 Family of unknown function (DUF5344) Sec34 PF04136.15 CEP16051.1 - 4.2 7.2 23.2 3.9 7.3 10.2 2.2 1 1 0 2 2 2 0 Sec34-like family DUF641 PF04859.12 CEP16051.1 - 4.4 7.7 24.0 11 6.3 4.0 2.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF2203 PF09969.9 CEP16051.1 - 5 7.9 22.6 7 7.4 6.9 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cep57_CLD PF14073.6 CEP16051.1 - 5.4 7.0 34.9 6.9 6.7 10.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Rx_N PF18052.1 CEP16051.1 - 6.4 7.1 20.3 0.15 12.3 1.7 3.4 1 1 1 2 2 1 0 Rx N-terminal domain COG2 PF06148.11 CEP16051.1 - 6.4 6.9 21.4 5.4 7.1 4.5 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5082 PF16888.5 CEP16051.1 - 6.7 7.0 29.6 2.4e+03 -1.2 29.6 2.5 1 1 0 1 1 0 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 CEP16051.1 - 7.4 6.8 36.7 0.48 10.6 3.9 4.5 2 2 2 4 4 4 0 bZIP transcription factor Occludin_ELL PF07303.13 CEP16051.1 - 7.7 7.3 19.9 24 5.8 6.1 2.8 1 1 1 2 2 2 0 Occludin homology domain DUF4795 PF16043.5 CEP16051.1 - 8 6.0 34.1 21 4.7 34.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Jnk-SapK_ap_N PF09744.9 CEP16051.1 - 8.1 6.7 37.3 49 4.1 27.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.19 CEP16051.1 - 8.4 6.1 38.2 37 4.0 38.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family LPP PF04728.13 CEP16051.1 - 9.7 6.7 19.2 1.4 9.4 1.6 4.6 1 1 3 4 4 4 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 CEP16051.1 - 9.7 6.2 41.0 28 4.7 3.8 4.2 1 1 1 2 2 1 0 Prefoldin subunit Ribosomal_L37ae PF01780.19 CEP16052.1 - 2.6e-41 139.6 13.0 2.9e-41 139.5 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CEP16052.1 - 0.00097 19.2 3.2 0.0014 18.7 3.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CEP16052.1 - 0.0015 18.5 1.8 0.0023 17.9 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 CEP16052.1 - 0.014 15.4 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 CEP16052.1 - 0.022 14.4 2.9 2.9 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-FCS PF06467.14 CEP16052.1 - 0.036 14.0 3.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 CEP16052.1 - 0.12 12.7 2.9 4.5 7.7 3.3 2.0 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 CEP16052.1 - 0.93 9.6 5.6 4 7.5 0.6 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CEP16052.1 - 4.2 8.0 7.3 2.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Kelch_5 PF13854.6 CEP16053.1 - 8.6e-25 86.3 5.4 2.8e-06 27.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CEP16053.1 - 2.4e-21 75.5 11.2 5.7e-09 35.9 0.4 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP16053.1 - 1.2e-20 73.0 9.9 1.2e-05 25.4 0.1 5.6 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CEP16053.1 - 1.7e-17 62.6 0.1 0.0023 17.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CEP16053.1 - 3.4e-14 52.7 3.7 0.016 15.5 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain BTB PF00651.31 CEP16053.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.25 CEP16053.1 - 2.2e-11 43.2 0.2 0.0037 16.8 0.1 4.6 4 0 0 4 4 4 3 Kelch motif BACK PF07707.15 CEP16053.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ribosomal_L29 PF00831.23 CEP16054.1 - 3.1e-15 55.9 2.9 3.1e-15 55.9 2.9 2.1 1 1 1 2 2 2 1 Ribosomal L29 protein HSP90 PF00183.18 CEP16055.1 - 6.1e-233 774.4 29.9 7.5e-233 774.1 29.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CEP16055.1 - 5e-15 56.0 0.0 1e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP16055.1 - 1.5e-10 41.0 1.9 1.8e-10 40.8 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 CEP16055.1 - 0.15 12.0 1.2 0.26 11.3 0.0 2.0 3 0 0 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN MFS_1_like PF12832.7 CEP16056.1 - 9.7e-42 143.2 13.6 1.4e-41 142.7 13.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CEP16056.1 - 8.4e-15 54.5 33.0 1.4e-14 53.8 5.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CEP16056.1 - 3.4e-10 39.5 15.5 7.1e-10 38.4 8.8 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter Methyltransf_11 PF08241.12 CEP16057.1 - 5e-14 52.7 0.0 9.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP16057.1 - 1e-13 51.8 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP16057.1 - 1.3e-11 44.6 0.0 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP16057.1 - 1e-08 35.2 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP16057.1 - 1.6e-07 32.0 0.0 2.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP16057.1 - 3.4e-06 26.6 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CEP16057.1 - 0.00019 21.0 0.0 0.00053 19.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 CEP16057.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 CEP16057.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 CEP16057.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 CEP16057.1 - 0.034 13.5 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 CEP16057.1 - 0.15 11.9 0.0 0.75 9.6 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF938 PF06080.12 CEP16057.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Mucin PF01456.17 CEP16057.1 - 0.46 10.5 14.5 0.15 12.1 7.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Acyl-CoA_dh_1 PF00441.24 CEP16058.1 - 4.7e-49 166.5 3.1 7.5e-49 165.8 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CEP16058.1 - 2.4e-28 98.1 0.4 6e-28 96.9 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CEP16058.1 - 2.9e-25 89.1 0.1 5.6e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CEP16058.1 - 4e-18 66.0 1.1 6.6e-18 65.3 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CEP16058.1 - 0.00012 21.9 0.3 0.00034 20.4 0.3 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Spc7 PF08317.11 CEP16059.1 - 0.0013 17.6 45.5 0.0027 16.7 20.6 2.9 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 CEP16059.1 - 0.0021 17.4 16.8 0.0021 17.4 16.8 3.5 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Mt_ATP-synt_D PF05873.12 CEP16059.1 - 2 8.2 12.5 1.5 8.7 3.8 3.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fez1 PF06818.15 CEP16059.1 - 2.5 8.5 49.8 0.74 10.2 14.3 3.4 2 1 1 3 3 3 0 Fez1 TSC22 PF01166.18 CEP16059.1 - 2.6 8.4 21.6 6.8 7.1 0.1 4.8 3 2 1 4 4 4 0 TSC-22/dip/bun family APG6_N PF17675.1 CEP16059.1 - 3.6 8.1 47.8 3.4 8.2 14.9 3.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 CEP16059.1 - 7.1 6.2 51.6 11 5.7 23.4 3.2 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 CEP16059.1 - 7.4 5.9 57.3 0.013 15.0 19.8 3.9 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal HOOK PF05622.12 CEP16059.1 - 8.4 4.4 47.1 10 4.2 31.3 3.0 1 1 2 3 3 3 0 HOOK protein TPR_MLP1_2 PF07926.12 CEP16059.1 - 9.8 6.3 58.4 0.47 10.5 16.2 5.2 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein HBS1_N PF08938.10 CEP16060.1 - 1.6e-17 63.6 5.6 1.9e-17 63.3 5.6 1.1 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.27 CEP16061.1 - 2.1e-46 158.0 0.0 4e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CEP16061.1 - 6.7e-23 81.1 0.2 3.3e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CEP16061.1 - 3.9e-06 26.9 0.0 0.00023 21.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CEP16061.1 - 0.00013 22.3 0.1 0.00031 21.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CEP16061.1 - 0.0018 18.2 0.6 0.0061 16.4 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Ras PF00071.22 CEP16061.1 - 0.015 14.9 2.1 0.36 10.4 0.0 2.6 3 0 0 3 3 3 0 Ras family Roc PF08477.13 CEP16061.1 - 0.02 15.1 0.0 7.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CEP16061.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CEP16061.1 - 0.072 12.5 0.9 0.5 9.8 0.0 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF1120 PF06551.12 CEP16061.1 - 0.17 12.1 2.0 0.83 9.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) Pkinase PF00069.25 CEP16062.1 - 4.3e-20 72.2 0.0 5.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16062.1 - 4.7e-09 35.9 0.0 6.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mem_trans PF03547.18 CEP16063.1 - 9.4e-47 159.2 12.0 1.2e-46 158.8 12.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Dynein_light PF01221.18 CEP16063.1 - 2.3e-29 101.6 0.7 4.4e-29 100.6 0.7 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 T2SSC PF11356.8 CEP16064.1 - 0.11 12.4 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Type II secretion system protein C FliS PF02561.14 CEP16065.1 - 0.039 14.2 0.5 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 Flagellar protein FliS DIOX_N PF14226.6 CEP16066.1 - 1.2e-27 96.9 0.6 2.5e-27 95.9 0.6 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CEP16066.1 - 2.2e-20 73.0 0.0 4.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mitoc_mL59 PF18126.1 CEP16067.1 - 1.2e-10 41.8 7.0 1.8e-09 38.0 7.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 CEP16067.1 - 0.0049 16.6 5.7 0.0079 15.9 5.7 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Spem1 PF15670.5 CEP16067.1 - 0.029 13.9 0.5 0.038 13.6 0.5 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF865 PF05906.11 CEP16067.1 - 0.24 11.2 0.8 0.42 10.5 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L19e PF01280.20 CEP16068.1 - 8.4e-61 204.3 9.5 8.4e-61 204.3 9.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e Alpha_TIF PF02232.15 CEP16068.1 - 0.051 12.7 0.9 0.075 12.1 0.9 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) E1_DerP2_DerF2 PF02221.15 CEP16069.1 - 7.1e-06 26.5 0.0 8.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 ML domain Yae1_N PF09811.9 CEP16070.1 - 7.5e-08 31.9 3.2 1e-07 31.5 3.2 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal HisKA_2 PF07568.12 CEP16070.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase Ribosomal_S7 PF00177.21 CEP16071.1 - 9.4e-35 119.4 0.9 1.2e-34 119.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HMGL-like PF00682.19 CEP16071.1 - 0.09 12.3 0.4 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 HMGL-like MFS_1 PF07690.16 CEP16072.1 - 4e-28 98.3 46.2 7.6e-17 61.3 20.8 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Kinesin PF00225.23 CEP16073.1 - 5.3e-45 153.8 0.2 1.3e-44 152.5 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEP16073.1 - 7.7e-05 22.7 0.0 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding ThrE PF06738.12 CEP16074.1 - 2.9e-52 177.4 18.8 4.1e-46 157.3 3.8 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CEP16074.1 - 3.3e-11 43.4 9.2 3.3e-11 43.4 9.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF4195 PF13836.6 CEP16074.1 - 0.14 12.3 6.4 0.042 14.0 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) Suc_Fer-like PF06999.12 CEP16075.1 - 2.2e-30 106.0 0.0 2.8e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF460 PF04312.13 CEP16075.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) PPR_2 PF13041.6 CEP16076.1 - 1.1e-61 204.8 20.8 2.1e-11 43.8 0.1 9.3 5 3 4 9 9 9 7 PPR repeat family PPR PF01535.20 CEP16076.1 - 8.3e-43 141.7 13.1 1.8e-06 27.8 0.0 11.9 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 CEP16076.1 - 8.2e-42 141.1 15.8 1.8e-12 47.2 0.1 8.1 3 2 6 9 9 9 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 CEP16076.1 - 2.2e-41 139.2 7.8 2.5e-05 23.9 0.0 10.3 10 0 0 10 10 10 8 PPR repeat PPR_long PF17177.4 CEP16076.1 - 1.8e-18 66.7 0.0 6e-07 29.0 0.0 4.5 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 CEP16076.1 - 9.1e-08 31.4 1.3 6.5e-05 22.0 0.1 3.6 2 1 3 5 5 5 1 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 CEP16076.1 - 2.9e-05 24.5 2.2 1.2 9.6 0.0 4.8 4 1 1 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 CEP16076.1 - 0.00015 21.6 3.6 1.3 8.9 0.1 5.2 3 1 3 6 6 6 1 Mitochondrial ATPase expression IlvC PF01450.19 CEP16076.1 - 0.031 14.5 0.3 5.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain ID PF18543.1 CEP16076.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Intracellular delivery domain Peptidase_M16 PF00675.20 CEP16076.1 - 0.17 11.9 1.1 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) SelP_N PF04592.14 CEP16078.1 - 1.3 8.3 28.6 2.2 7.6 2.4 2.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region WD40 PF00400.32 CEP16079.1 - 3.7e-45 151.0 30.8 1e-08 35.7 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16079.1 - 6.5e-16 58.4 7.7 0.0047 17.2 0.4 6.0 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEP16079.1 - 0.12 10.3 9.4 0.66 7.9 0.7 2.6 2 1 1 3 3 3 0 IKI3 family Coatomer_WDAD PF04053.14 CEP16079.1 - 0.19 10.7 3.6 0.6 9.1 1.3 2.6 2 1 0 2 2 2 0 Coatomer WD associated region Serine_protease PF18405.1 CEP16080.1 - 0.072 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Citrate_synt PF00285.21 CEP16081.1 - 2.7e-104 349.1 0.0 3.4e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain V-ATPase_H_N PF03224.14 CEP16084.1 - 7e-59 199.7 8.5 5.8e-38 130.9 1.2 2.8 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 CEP16084.1 - 2e-42 144.0 1.3 4.3e-42 142.9 0.2 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 CEP16084.1 - 0.0066 16.5 0.5 35 4.6 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP16084.1 - 0.0096 16.3 0.1 0.062 13.7 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats CelTOS PF18659.1 CEP16084.1 - 0.046 14.2 0.5 0.11 12.9 0.2 1.8 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites HEAT PF02985.22 CEP16084.1 - 0.078 13.3 0.1 0.8 10.1 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat RhoGAP PF00620.27 CEP16084.1 - 0.18 11.6 1.2 0.78 9.5 0.4 2.3 2 1 0 2 2 2 0 RhoGAP domain Terminase_2 PF03592.16 CEP16084.1 - 0.28 11.6 2.5 8.9 6.8 0.4 2.5 2 0 0 2 2 2 0 Terminase small subunit TPR_1 PF00515.28 CEP16085.1 - 3.3e-16 58.3 5.6 3.8e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP16085.1 - 5.8e-12 44.8 9.6 0.00073 19.5 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP16085.1 - 2.2e-09 36.8 2.6 7.4e-06 25.5 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CEP16085.1 - 1.7e-08 34.0 8.4 0.0013 18.8 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP16085.1 - 4.4e-08 33.5 0.5 2.9e-06 27.7 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat FKBP_C PF00254.28 CEP16085.1 - 1.4e-07 31.7 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_12 PF13424.6 CEP16085.1 - 6.7e-07 29.5 5.9 9e-06 25.9 0.3 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP16085.1 - 8.2e-07 28.6 1.6 0.01 15.8 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP16085.1 - 2.9e-06 27.8 0.0 0.0003 21.4 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP16085.1 - 5e-05 23.4 0.0 0.00017 21.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP16085.1 - 5.8e-05 23.6 1.0 0.035 14.9 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP16085.1 - 9e-05 22.9 0.9 0.12 13.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP16085.1 - 9.2e-05 22.6 1.8 0.00038 20.6 1.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CEP16085.1 - 0.00048 20.1 4.9 1 9.5 0.1 3.3 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 CEP16085.1 - 0.024 14.0 0.5 1.1 8.6 0.1 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit TPR_9 PF13371.6 CEP16085.1 - 0.043 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 CEP16085.1 - 0.099 12.3 4.8 2.9 7.5 1.8 3.0 1 1 2 3 3 3 0 26S proteasome subunit RPN7 MIT PF04212.18 CEP16085.1 - 0.28 11.3 6.3 2.1 8.4 0.9 3.6 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF4061 PF13270.6 CEP16086.1 - 0.00013 22.2 0.1 0.00013 22.2 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4061) PAP2 PF01569.21 CEP16087.1 - 6.2e-32 110.2 1.8 6.2e-32 110.2 1.8 2.2 2 2 0 2 2 2 1 PAP2 superfamily DUF805 PF05656.14 CEP16087.1 - 0.016 15.6 1.0 3.3 8.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) COX2_TM PF02790.15 CEP16087.1 - 0.1 12.8 1.3 0.2 11.8 1.3 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain PAP2_3 PF14378.6 CEP16087.1 - 0.82 9.3 8.1 1.4 8.6 2.7 3.0 2 1 1 3 3 3 0 PAP2 superfamily PAP2_C PF14360.6 CEP16087.1 - 3.2 8.4 9.0 0.25 11.9 1.4 2.7 2 1 1 3 3 3 0 PAP2 superfamily C-terminal PMT PF02366.18 CEP16088.1 - 5.1e-77 258.8 22.8 1.1e-76 257.7 22.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEP16088.1 - 7.2e-61 205.3 9.0 7.2e-61 205.3 9.0 3.3 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEP16088.1 - 2.4e-07 30.8 0.0 7.5e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 MIR domain Choline_kinase PF01633.20 CEP16089.1 - 1.1e-61 208.1 0.0 2.3e-61 207.1 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CEP16089.1 - 8e-16 58.7 0.0 1.3e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CEP16089.1 - 0.0021 17.4 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Melibiase_C PF17801.1 CEP16090.1 - 4.1e-12 46.0 0.1 8e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2 PF16499.5 CEP16090.1 - 2.9e-10 39.8 2.3 6.9e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Glyco_hydro_31 PF01055.26 CEP16090.1 - 2.4e-07 30.3 0.4 5.4e-07 29.2 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 CEP16090.1 - 7e-06 25.2 0.4 9.3e-05 21.5 0.1 2.2 2 0 0 2 2 2 1 Melibiase DDHD PF02862.17 CEP16091.1 - 2.7e-41 142.2 0.0 2.7e-41 142.2 0.0 3.9 3 1 0 3 3 3 1 DDHD domain WWE PF02825.20 CEP16091.1 - 2.1e-05 25.0 0.6 0.0037 17.8 0.0 2.8 1 1 1 2 2 2 2 WWE domain Secretin_N_2 PF07655.13 CEP16091.1 - 8.7 7.0 23.1 2.1 9.0 5.3 3.7 3 0 0 3 3 3 0 Secretin N-terminal domain Pro_isomerase PF00160.21 CEP16092.1 - 1.1e-51 175.2 0.6 3.5e-51 173.6 0.2 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PIF1 PF05970.14 CEP16092.1 - 4.3e-11 42.6 0.0 8.3e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase Rtf2 PF04641.12 CEP16092.1 - 4.1e-06 26.4 1.7 4.1e-06 26.4 1.7 2.6 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CEP16092.1 - 1.8e-05 24.8 0.2 0.0001 22.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 CEP16092.1 - 0.0013 18.8 0.1 0.046 13.9 0.0 2.8 1 1 1 2 2 2 1 U-box domain zf-C2H2 PF00096.26 CEP16093.1 - 2.1e-08 34.1 21.6 0.0015 18.8 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP16093.1 - 4e-07 30.2 17.4 0.00016 21.9 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP16093.1 - 3.7e-06 27.3 19.8 0.0024 18.5 0.5 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP16093.1 - 0.02 14.9 6.9 0.14 12.2 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Herpes_BLLF1 PF05109.13 CEP16093.1 - 0.037 12.0 3.6 0.055 11.4 3.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) FOXP-CC PF16159.5 CEP16093.1 - 0.13 12.9 11.5 0.22 12.2 0.1 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEP16093.1 - 0.15 12.4 5.2 0.089 13.1 2.6 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CEP16093.1 - 0.18 11.6 0.3 0.18 11.6 0.3 2.4 3 0 0 3 3 2 0 zinc-finger C2H2-type DUF4666 PF15697.5 CEP16093.1 - 0.2 12.4 8.5 0.34 11.6 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) zf-Di19 PF05605.12 CEP16093.1 - 0.2 12.0 14.8 0.38 11.1 0.1 3.1 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CEP16093.1 - 0.22 11.3 17.2 0.39 10.5 6.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GREB1 PF15782.5 CEP16093.1 - 0.64 7.1 9.4 0.79 6.8 9.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 CEP16093.1 - 0.89 7.8 6.2 1.4 7.2 6.2 1.3 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 CEP16093.1 - 1.1 8.1 8.9 1.3 7.8 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CEP16093.1 - 5.9 5.0 10.2 7.7 4.7 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NST1 PF13945.6 CEP16093.1 - 6.2 6.9 14.2 1.5 8.9 11.0 1.5 2 0 0 2 2 2 0 Salt tolerance down-regulator Presenilin PF01080.17 CEP16093.1 - 9.8 4.8 8.5 13 4.5 8.5 1.1 1 0 0 1 1 1 0 Presenilin SEP PF08059.13 CEP16094.1 - 6e-27 94.0 0.0 1.4e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CEP16094.1 - 1.3e-17 63.8 0.0 2.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CEP16094.1 - 4.6e-14 52.0 0.9 7.6e-14 51.3 0.9 1.3 1 0 0 1 1 1 1 UBA-like domain LEA_2 PF03168.13 CEP16095.1 - 1.9e-05 25.1 0.0 3.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2897 PF11446.8 CEP16095.1 - 0.029 14.2 2.1 0.055 13.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) FixS PF03597.15 CEP16095.1 - 4.4 7.1 5.1 8.4 6.2 5.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Coq4 PF05019.13 CEP16096.1 - 7.2e-95 316.5 0.0 8.2e-95 316.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 XylR_N PF06505.11 CEP16096.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Activator of aromatic catabolism RPAP2_Rtr1 PF04181.13 CEP16098.1 - 6.9e-21 74.4 2.3 6.9e-21 74.4 2.3 2.4 2 0 0 2 2 2 1 Rtr1/RPAP2 family FixG_C PF11614.8 CEP16098.1 - 0.074 13.3 5.9 0.24 11.6 0.4 2.5 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase CRA PF06589.11 CEP16098.1 - 0.23 11.6 5.4 0.16 12.1 1.4 2.5 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) CK_II_beta PF01214.18 CEP16099.1 - 9.4e-70 234.1 0.2 2.3e-69 232.9 0.2 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PTPRCAP PF15713.5 CEP16099.1 - 9.4 6.5 14.9 1.4 9.2 0.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated bZIP_2 PF07716.15 CEP16100.1 - 1.8e-09 37.5 6.5 1.8e-09 37.5 6.5 1.6 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 CEP16100.1 - 4.7e-09 36.2 7.8 8.4e-09 35.4 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor ADIP PF11559.8 CEP16100.1 - 0.0033 17.5 5.4 0.0045 17.1 5.4 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Mto2_bdg PF12808.7 CEP16100.1 - 0.01 16.1 2.3 0.01 16.1 2.3 1.8 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_Maf PF03131.17 CEP16100.1 - 0.011 16.2 7.2 0.017 15.7 7.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2400 PF09674.10 CEP16100.1 - 0.011 15.7 0.2 0.013 15.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) APG6_N PF17675.1 CEP16100.1 - 0.021 15.3 2.0 0.031 14.8 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region RNA_pol_Rpb1_6 PF04992.14 CEP16100.1 - 0.025 14.4 0.9 0.033 14.0 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Dicer_dimer PF03368.14 CEP16100.1 - 0.029 14.5 0.3 0.039 14.1 0.3 1.3 1 0 0 1 1 1 0 Dicer dimerisation domain EMP24_GP25L PF01105.24 CEP16100.1 - 0.04 13.8 1.2 0.051 13.5 1.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZapB PF06005.12 CEP16100.1 - 0.075 13.5 3.5 0.1 13.1 2.9 1.4 1 1 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CEP16100.1 - 0.24 12.1 4.0 0.45 11.2 3.9 1.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF2937 PF11157.8 CEP16100.1 - 0.46 10.2 2.1 0.65 9.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) HIT PF01230.23 CEP16102.1 - 1.3e-22 80.3 0.6 3.9e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CEP16102.1 - 1.9e-08 34.8 0.0 3.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CEP16102.1 - 3.4e-05 23.7 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AMP-binding PF00501.28 CEP16104.1 - 2.7e-87 293.1 0.0 3.9e-86 289.3 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP16104.1 - 2.5e-14 54.0 0.4 5.1e-14 53.0 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CEP16105.1 - 3.6e-51 174.2 47.0 7.3e-51 173.1 45.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP16105.1 - 5.9e-13 48.5 11.6 5.9e-13 48.5 11.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEP16105.1 - 1e-12 47.3 25.2 1e-12 47.3 25.2 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CEP16105.1 - 4.9e-05 22.3 7.9 4.9e-05 22.3 7.9 2.3 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 CEP16105.1 - 0.26 9.5 22.1 1.8 6.8 16.0 3.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YrhC PF14143.6 CEP16105.1 - 1.7 8.8 7.7 6.7 6.9 0.0 4.0 4 0 0 4 4 4 0 YrhC-like protein DUF3377 PF11857.8 CEP16105.1 - 1.8 8.5 6.5 0.69 9.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Ras PF00071.22 CEP16107.1 - 3.7e-56 189.2 0.0 4.2e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP16107.1 - 5.6e-21 75.0 0.0 7.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP16107.1 - 1.9e-08 34.0 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEP16107.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CEP16107.1 - 0.041 13.8 0.1 0.17 11.8 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 CEP16107.1 - 0.16 11.3 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Hormone_2 PF00123.20 CEP16110.1 - 0.047 13.6 0.5 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Peptide hormone Pkinase PF00069.25 CEP16111.1 - 1.6e-63 214.6 0.0 2.9e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16111.1 - 3.7e-34 118.2 0.0 6.8e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CEP16111.1 - 4.6e-19 68.0 24.7 7e-11 41.8 9.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CEP16111.1 - 2.7e-09 37.6 0.5 1.3e-08 35.4 0.5 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 CEP16111.1 - 2.1e-07 31.0 20.7 0.00012 22.1 5.9 3.4 3 0 0 3 3 3 2 Hr1 repeat C2 PF00168.30 CEP16111.1 - 1.1e-05 25.6 0.1 2.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 CEP16111.1 - 0.011 14.7 6.3 0.032 13.2 6.3 1.8 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEP16111.1 - 0.019 14.6 0.2 1.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PHD_2 PF13831.6 CEP16111.1 - 0.58 9.8 12.8 2.3 7.8 2.8 2.6 2 0 0 2 2 2 0 PHD-finger C1_2 PF03107.16 CEP16111.1 - 8.9 6.7 19.4 8.2 6.8 6.3 2.7 2 0 0 2 2 2 0 C1 domain RT_RNaseH PF17917.1 CEP16113.1 - 2.4e-11 43.9 0.0 3.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4729 PF15866.5 CEP16113.1 - 0.034 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Retrotrans_gag PF03732.17 CEP16115.1 - 0.039 14.2 2.6 0.074 13.3 0.1 2.5 2 1 1 3 3 3 0 Retrotransposon gag protein HHH_4 PF14490.6 CEP16119.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain FSAP_sig_propep PF03032.15 CEP16119.1 - 5.9 7.0 7.8 0.45 10.6 1.7 2.3 2 0 0 2 2 2 0 Frog skin active peptide family signal and propeptide SPA PF08616.10 CEP16120.1 - 4.6e-12 45.9 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CEP16120.1 - 2.3e-05 23.3 0.0 5.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 CEP16120.1 - 0.07 13.1 0.3 3.8 7.4 0.3 2.4 1 1 0 1 1 1 0 DENN (AEX-3) domain FAM72 PF14976.6 CEP16122.1 - 3.2e-50 170.1 5.8 4.8e-50 169.5 5.8 1.2 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 CEP16122.1 - 0.15 12.3 8.1 0.29 11.4 8.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DHHC PF01529.20 CEP16123.1 - 1.8e-06 28.1 3.4 3e-06 27.4 3.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase UPF0114 PF03350.16 CEP16123.1 - 0.013 15.6 0.5 0.023 14.9 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 COG5 PF10392.9 CEP16124.1 - 3.5e-27 95.2 5.7 3.5e-27 95.2 5.7 3.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 CEP16124.1 - 4.3e-06 26.7 1.2 4.3e-06 26.7 1.2 3.2 3 0 0 3 3 3 1 Vps51/Vps67 Vps54_N PF10475.9 CEP16124.1 - 0.0023 17.3 5.5 0.0023 17.3 5.5 2.7 1 1 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 CEP16124.1 - 0.18 11.9 2.5 1.2 9.2 2.5 2.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc42p PF11544.8 CEP16124.1 - 0.39 10.8 3.1 15 5.6 0.1 2.9 1 1 1 2 2 2 0 Spindle pole body component Spc42p RRM_1 PF00076.22 CEP16125.1 - 8.9e-72 236.9 0.2 3.1e-19 68.6 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP16125.1 - 1.5e-17 63.5 1.6 4.5e-17 62.0 1.6 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 CEP16125.1 - 1.5e-09 37.8 1.6 0.0078 16.3 0.0 3.7 3 0 0 3 3 3 3 Limkain b1 RRM_5 PF13893.6 CEP16125.1 - 2.5e-08 33.6 0.1 0.0021 17.6 0.0 3.5 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DSPc PF00782.20 CEP16125.1 - 9.5e-07 28.7 0.0 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RRM_occluded PF16842.5 CEP16125.1 - 0.00042 20.1 0.0 2.5 8.0 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CEP16125.1 - 0.00049 20.2 0.0 22 5.3 0.0 4.6 4 1 0 4 4 4 0 RNA recognition motif Y_phosphatase PF00102.27 CEP16125.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CEP16125.1 - 0.0042 16.8 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Nup35_RRM_2 PF14605.6 CEP16125.1 - 0.005 16.8 0.1 10 6.2 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 CEP16125.1 - 0.0071 16.8 0.5 6.7 7.3 0.1 2.5 2 0 0 2 2 2 2 Heat induced stress protein YflT RRM_3 PF08777.11 CEP16125.1 - 0.0075 16.3 0.5 0.25 11.4 0.1 3.3 4 0 0 4 4 4 1 RNA binding motif DUF442 PF04273.13 CEP16125.1 - 0.019 15.0 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Putative phosphatase (DUF442) TyeA PF09059.10 CEP16126.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 TyeA IML1 PF12257.8 CEP16127.1 - 8.8e-118 392.6 0.0 2.7e-116 387.7 0.1 2.9 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CEP16127.1 - 2.1e-20 72.6 0.1 2.2e-19 69.3 0.1 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DnaJ PF00226.31 CEP16127.1 - 2.2e-16 59.7 0.2 7.1e-16 58.1 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 CEP16127.1 - 0.32 10.9 58.8 0.07 13.1 12.1 3.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEP16127.1 - 4.6 6.8 59.2 0.023 14.3 16.4 3.6 3 0 0 3 3 3 0 Spt20 family HLH PF00010.26 CEP16128.1 - 1.7e-12 47.1 2.9 3.9e-12 45.9 2.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt20 PF12090.8 CEP16128.1 - 0.0016 18.1 19.5 0.0016 18.1 19.5 2.4 2 0 0 2 2 2 1 Spt20 family PhoU_div PF01865.16 CEP16128.1 - 0.0087 15.4 0.7 0.021 14.1 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF47 Nha1_C PF08619.10 CEP16128.1 - 4.6 6.3 24.8 0.027 13.7 16.0 1.7 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus FAM176 PF14851.6 CEP16128.1 - 9.1 5.9 8.8 22 4.7 8.8 1.6 1 0 0 1 1 1 0 FAM176 family Porin_3 PF01459.22 CEP16129.1 - 3.9e-69 233.1 1.8 4.7e-69 232.9 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic porin tRNA-synt_2 PF00152.20 CEP16130.1 - 1e-93 313.9 0.0 1.3e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEP16130.1 - 1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEP16130.1 - 0.048 13.1 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Uricase PF01014.18 CEP16131.1 - 2.4e-66 221.9 2.7 1e-32 113.1 0.1 2.1 2 0 0 2 2 2 2 Uricase GlcV_C_terminal PF17847.1 CEP16131.1 - 0.056 13.9 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Glucose ABC transporter C-terminal domain Ribosomal_L17 PF01196.19 CEP16131.1 - 0.082 13.8 0.0 0.21 12.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L17 TruD PF01142.18 CEP16132.1 - 3.7e-72 243.4 0.0 1.2e-69 235.2 0.0 2.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) rRNA_methylase PF06962.12 CEP16132.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Med20 PF08612.11 CEP16133.1 - 3.5e-30 105.1 0.1 3.9e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_hydro_63N PF16923.5 CEP16133.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain Prok-E2_D PF14460.6 CEP16133.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family D GPI-anchored PF10342.9 CEP16134.1 - 2.1e-12 47.6 3.1 2.1e-12 47.6 3.1 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5626 PF18540.1 CEP16134.1 - 0.074 13.6 7.6 0.18 12.3 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5626) Myb_DNA-bind_6 PF13921.6 CEP16135.1 - 0.00039 20.6 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP16135.1 - 0.0019 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain RraA-like PF03737.15 CEP16136.1 - 5.2e-36 124.1 0.0 6.5e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Fcf2 PF08698.11 CEP16138.1 - 3.7e-37 126.6 4.7 3.7e-37 126.6 4.7 3.1 3 1 0 3 3 3 1 Fcf2 pre-rRNA processing DUF1604 PF07713.13 CEP16138.1 - 0.03 14.1 0.5 0.03 14.1 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1604) Atrophin-1 PF03154.15 CEP16138.1 - 0.033 12.5 13.8 0.041 12.2 13.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family GREB1 PF15782.5 CEP16138.1 - 4.4 4.3 16.0 5.5 4.0 16.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ETF PF01012.21 CEP16139.1 - 1.6e-49 168.3 1.8 2e-49 167.9 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HTH_23 PF13384.6 CEP16140.1 - 3e-06 26.9 0.0 6.6e-06 25.8 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP16140.1 - 0.0025 17.8 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_IclR PF09339.10 CEP16140.1 - 0.004 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 CEP16140.1 - 0.0042 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 CEP16140.1 - 0.006 16.7 0.0 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP16140.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 CEP16140.1 - 0.049 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain LRR_6 PF13516.6 CEP16141.1 - 9.3e-10 37.8 35.1 0.23 11.6 0.0 10.2 11 0 0 11 11 11 5 Leucine Rich repeat UBX PF00789.20 CEP16141.1 - 3.7e-06 27.0 0.2 1.1e-05 25.6 0.2 1.8 1 0 0 1 1 1 1 UBX domain LRR_4 PF12799.7 CEP16141.1 - 5.5e-06 26.6 47.2 0.13 12.8 3.3 8.8 5 4 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP16141.1 - 2.2e-05 24.1 5.6 0.00032 20.4 2.3 6.5 3 2 4 7 7 7 4 Leucine rich repeat UBA PF00627.31 CEP16141.1 - 0.054 13.4 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 UBA/TS-N domain PEHE PF15275.6 CEP16141.1 - 7.4 7.2 10.3 21 5.8 9.9 2.1 1 1 0 1 1 1 0 PEHE domain Rhomboid PF01694.22 CEP16142.1 - 0.029 14.4 2.1 0.049 13.6 2.1 1.4 1 0 0 1 1 1 0 Rhomboid family MerR_1 PF13411.6 CEP16142.1 - 0.16 12.0 0.4 0.41 10.8 0.4 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein Acetyltransf_1 PF00583.25 CEP16143.1 - 6.8e-05 23.1 0.0 0.00016 21.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP16143.1 - 0.031 14.7 0.0 0.056 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FUSC_2 PF13515.6 CEP16144.1 - 9.2e-20 71.0 9.3 9.2e-20 71.0 9.3 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEP16144.1 - 9.9e-12 44.2 2.0 9.9e-12 44.2 2.0 3.1 3 1 0 3 3 3 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 CEP16144.1 - 3.5e-11 43.4 0.3 7e-11 42.4 0.3 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CEP16144.1 - 7.8e-09 34.9 0.8 7.8e-09 34.9 0.8 4.3 3 1 1 4 4 4 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 CEP16144.1 - 1.7e-08 34.0 0.1 1.7e-08 34.0 0.1 3.1 2 1 2 4 4 4 1 Putative ER transporter, 6TM, N-terminal Phage_holin_3_3 PF16083.5 CEP16144.1 - 0.0043 17.1 0.0 0.018 15.1 0.0 2.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Holin_BhlA PF10960.8 CEP16144.1 - 0.079 12.9 0.0 0.84 9.6 0.0 2.9 2 0 0 2 2 2 0 BhlA holin family CDC45 PF02724.14 CEP16144.1 - 0.52 8.6 14.6 0.011 14.0 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF2115 PF09888.9 CEP16144.1 - 2 8.9 5.7 6.9 7.2 5.7 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SLC12 PF03522.15 CEP16144.1 - 4 6.4 24.7 0.28 10.2 2.7 2.2 2 0 0 2 2 2 0 Solute carrier family 12 SHR3_chaperone PF08229.11 CEP16145.1 - 1.2e-35 122.3 1.1 1.3e-35 122.1 1.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DAGK_prokar PF01219.19 CEP16145.1 - 0.48 10.3 4.0 0.21 11.4 1.7 1.7 2 1 0 2 2 2 0 Prokaryotic diacylglycerol kinase Aminotran_5 PF00266.19 CEP16146.1 - 4e-23 82.0 0.0 4.9e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 CEP16146.1 - 0.023 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase SWIM PF04434.17 CEP16147.1 - 0.0071 16.0 0.3 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger Herpes_TK PF00693.18 CEP16147.1 - 0.022 14.0 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DUF179 PF02622.15 CEP16149.1 - 0.085 12.8 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 Oxysterol_BP PF01237.18 CEP16150.1 - 3.6e-89 299.2 1.1 3.9e-87 292.5 1.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein MIR PF02815.19 CEP16151.1 - 9e-18 64.8 0.3 1.4e-13 51.1 0.4 2.1 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 CEP16151.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Med26 PF08711.11 CEP16152.1 - 2e-13 50.1 0.0 4.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4404 PF14357.6 CEP16152.1 - 0.85 10.3 6.3 0.9 10.2 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Ribosomal_60s PF00428.19 CEP16153.1 - 9.6e-25 87.0 11.5 1.1e-24 86.8 11.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jag_N PF14804.6 CEP16153.1 - 0.056 13.8 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Jag N-terminus DPM2 PF07297.12 CEP16154.1 - 1e-25 89.8 2.5 1.1e-25 89.7 2.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RNA_pol_A_bac PF01000.26 CEP16155.1 - 3.9e-30 104.5 0.0 7.6e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CEP16155.1 - 1.5e-22 78.8 0.0 2.2e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Adeno_52K PF03052.15 CEP16155.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa DAHP_synth_1 PF00793.20 CEP16156.1 - 2.1e-69 233.4 0.0 2.6e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MTS PF05175.14 CEP16157.1 - 0.0054 16.3 0.1 1 8.9 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase small domain Methyltransf_16 PF10294.9 CEP16157.1 - 0.011 15.5 0.3 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase PCMT PF01135.19 CEP16157.1 - 0.013 15.2 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1770 PF08589.10 CEP16158.1 - 0.0045 17.9 0.6 0.0059 17.5 0.6 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PH_4 PF15404.6 CEP16159.1 - 6.8e-21 74.9 3.4 6.4e-18 65.2 3.4 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP16159.1 - 1.1e-08 35.5 3.3 4.7e-05 23.8 0.1 4.8 4 2 0 4 4 4 2 PH domain SOTI PF17079.5 CEP16159.1 - 0.08 13.3 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 Male-specific protein scotti DDE_3 PF13358.6 CEP16160.1 - 1.9e-06 27.7 0.1 8.9e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 CEP16160.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 CEP16160.1 - 4.7e-05 23.1 0.0 9.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 CEP16160.1 - 0.0013 19.3 0.0 0.0022 18.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP16160.1 - 0.0046 16.3 0.0 0.0099 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF2680 PF10925.8 CEP16160.1 - 0.044 13.8 2.0 0.091 12.8 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) HTH_28 PF13518.6 CEP16160.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.18 CEP16160.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain DUF3568 PF12092.8 CEP16160.1 - 0.56 10.3 3.5 1.2 9.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Glutaredoxin PF00462.24 CEP16161.1 - 8e-16 58.0 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin IGPS PF00218.21 CEP16162.1 - 7.1e-91 303.9 0.6 1.5e-90 302.9 0.1 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 CEP16162.1 - 2.6e-50 170.9 0.0 9.5e-43 146.2 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 CEP16162.1 - 4.2e-49 166.9 0.0 7.6e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEP16162.1 - 9e-10 38.7 0.4 4.2e-09 36.5 0.1 2.3 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 CEP16162.1 - 0.034 13.9 0.4 0.44 10.3 0.0 2.7 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Homeodomain PF00046.29 CEP16163.1 - 3.2e-16 58.9 3.2 3.2e-16 58.9 3.2 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CEP16163.1 - 0.0012 18.6 1.9 0.0018 18.2 0.3 2.0 2 0 0 2 2 2 1 Homeobox KN domain Ebola_NP PF05505.12 CEP16163.1 - 0.89 7.8 12.4 1.1 7.5 12.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2730 PF10805.8 CEP16167.1 - 0.088 12.9 1.4 0.17 12.0 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FAM76 PF16046.5 CEP16167.1 - 0.11 11.8 4.1 0.091 12.1 3.0 1.4 2 0 0 2 2 2 0 FAM76 protein Mit_KHE1 PF10173.9 CEP16167.1 - 0.25 11.4 3.2 2.2 8.4 3.2 2.1 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RVT_1 PF00078.27 CEP16168.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EzrA PF06160.12 CEP16169.1 - 0.029 12.5 0.1 0.039 12.1 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BLYB PF05289.11 CEP16169.1 - 0.06 13.6 1.5 2.4 8.4 0.1 2.5 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein Lipoprotein_11 PF03260.13 CEP16171.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein Not3 PF04065.15 CEP16172.1 - 0.0032 16.9 0.5 0.0057 16.1 0.5 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component DUF2572 PF10833.8 CEP16172.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) RVT_1 PF00078.27 CEP16173.1 - 4.8e-11 42.6 0.0 8.8e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP16173.1 - 4.1e-07 29.9 0.1 1.1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CEP16173.1 - 0.01 15.4 0.5 0.021 14.4 0.1 1.7 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family PIG-L PF02585.17 CEP16174.1 - 0.075 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase PYST-C1 PF09690.10 CEP16175.1 - 0.091 12.5 0.7 0.16 11.7 0.7 1.4 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) OrfB_Zn_ribbon PF07282.11 CEP16176.1 - 0.00044 20.1 0.2 0.00071 19.5 0.2 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.6 CEP16176.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO DUF2183 PF09949.9 CEP16177.1 - 3.6e-27 94.6 0.2 2e-26 92.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF535 PF04393.13 CEP16177.1 - 0.045 13.0 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Acetyltransf_1 PF00583.25 CEP16178.1 - 4.9e-17 62.2 0.0 6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP16178.1 - 6.5e-11 42.5 0.0 9.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP16178.1 - 8.4e-11 41.9 0.0 9.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP16178.1 - 1e-06 28.6 0.1 1.6e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP16178.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEP16178.1 - 0.017 15.8 0.0 0.02 15.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CEP16178.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP16178.1 - 0.024 14.8 0.1 0.028 14.6 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PKcGMP_CC PF16808.5 CEP16179.1 - 0.0066 16.3 1.7 0.0066 16.3 1.7 5.0 3 2 1 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SAE2 PF08573.10 CEP16179.1 - 0.71 11.0 25.7 0.19 12.8 12.6 4.7 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus SlyX PF04102.12 CEP16179.1 - 2.8 8.6 9.8 0.23 12.1 1.6 3.2 2 1 1 3 3 3 0 SlyX Fungal_TACC PF12709.7 CEP16179.1 - 3.7 8.1 14.0 0.28 11.6 4.1 3.1 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF883 PF05957.13 CEP16179.1 - 5.8 7.6 10.5 4.4 8.0 1.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) YlqD PF11068.8 CEP16179.1 - 7.7 6.9 21.1 1.5 9.2 6.3 2.8 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 CEP16179.1 - 7.8 5.8 11.7 2.1 7.7 8.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RhoGAP PF00620.27 CEP16180.1 - 2.2e-23 82.8 0.6 5.6e-23 81.4 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain MAP65_ASE1 PF03999.12 CEP16181.1 - 1.7e-57 195.5 44.1 5.5e-57 193.8 43.7 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF2336 PF10098.9 CEP16181.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) SPT6_acidic PF14632.6 CEP16181.1 - 1.7 9.3 13.8 0.089 13.4 6.9 2.5 3 0 0 3 3 3 0 Acidic N-terminal SPT6 DUF4208 PF13907.6 CEP16181.1 - 3.1 8.3 11.8 4 7.9 1.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) PBP1_TM PF14812.6 CEP16181.1 - 7.6 7.0 9.1 3.4 8.1 5.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyt-b5 PF00173.28 CEP16182.1 - 1.5e-22 79.5 0.2 1.8e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U62_UL91 PF17442.2 CEP16182.1 - 0.1 12.6 0.2 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins ELL PF10390.9 CEP16183.1 - 5.7e-10 39.2 3.2 5.7e-10 39.2 3.2 1.9 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL M-inducer_phosp PF06617.13 CEP16184.1 - 0.036 13.4 0.2 0.039 13.2 0.2 1.1 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF2222 PF09984.9 CEP16185.1 - 0.096 12.6 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) HLH PF00010.26 CEP16186.1 - 6.5e-13 48.4 3.1 8.2e-13 48.1 1.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sec66 PF09802.9 CEP16186.1 - 0.034 13.7 2.5 0.88 9.1 0.5 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 bZIP_1 PF00170.21 CEP16186.1 - 2 8.6 10.0 10 6.3 4.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor Vps39_2 PF10367.9 CEP16187.1 - 1.3e-35 122.2 0.8 6.6e-34 116.6 0.1 3.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CEP16187.1 - 1.4e-33 116.7 0.0 2.5e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 CEP16187.1 - 2.5e-14 53.5 14.7 4.4e-10 39.8 0.2 5.7 3 3 3 7 7 7 2 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CEP16187.1 - 2.2e-11 43.8 3.7 2.2e-11 43.8 3.7 3.3 4 0 0 4 4 4 1 Region in Clathrin and VPS HemX PF04375.14 CEP16187.1 - 0.00018 20.9 0.3 0.00045 19.6 0.3 1.6 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_14 PF13428.6 CEP16187.1 - 0.031 15.1 0.9 13 6.9 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEP16187.1 - 0.034 14.2 3.1 20 5.5 0.0 4.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP16187.1 - 0.066 13.1 3.8 2.6 8.0 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP16187.1 - 0.13 12.5 2.7 30 5.0 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP16187.1 - 0.59 10.4 6.3 6.3 7.2 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Dynein_light PF01221.18 CEP16188.1 - 0.032 14.5 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Dynein light chain type 1 DUF3918 PF13056.6 CEP16189.1 - 0.15 11.7 0.4 16 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Glyco_transf_20 PF00982.21 CEP16191.1 - 2.8e-156 520.9 0.0 3.9e-156 520.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP16191.1 - 1.1e-73 247.3 0.0 1.8e-73 246.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEP16191.1 - 3.5e-06 27.0 0.0 0.0076 16.0 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Ndr PF03096.14 CEP16194.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Ndr family CHASE9 PF17153.4 CEP16194.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Aminotran_3 PF00202.21 CEP16195.1 - 2.3e-115 385.5 0.0 2.8e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CEP16195.1 - 0.00017 20.9 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DNA_ligase_IV PF11411.8 CEP16195.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 DNA ligase IV PMT PF02366.18 CEP16196.1 - 9.7e-79 264.4 12.9 2e-78 263.4 12.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEP16196.1 - 3.5e-25 88.8 7.5 3.5e-25 88.8 7.5 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEP16196.1 - 1.1e-24 87.3 0.2 2.8e-24 86.0 0.2 1.6 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 CEP16197.1 - 1.6e-30 105.8 0.0 2.1e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP16197.1 - 2.2e-13 50.5 0.0 3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glyco_transf_22 PF03901.17 CEP16198.1 - 5.7e-82 276.2 22.3 7.2e-82 275.8 22.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4611 PF15387.6 CEP16199.1 - 0.013 15.7 1.9 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-RING_2 PF13639.6 CEP16200.1 - 3.7e-13 49.6 5.3 5.3e-13 49.1 5.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP16200.1 - 2.8e-10 39.7 2.6 2.8e-10 39.7 2.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CEP16200.1 - 1.1e-08 34.8 4.3 1.7e-08 34.2 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP16200.1 - 3.4e-08 33.2 5.3 5.2e-08 32.6 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP16200.1 - 1.7e-06 28.2 8.4 6.5e-06 26.3 8.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CEP16200.1 - 3.1e-06 26.9 2.3 4.6e-06 26.4 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP16200.1 - 1.4e-05 24.9 4.1 2.1e-05 24.4 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP16200.1 - 2.5e-05 24.2 2.6 0.0011 19.0 0.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CEP16200.1 - 3.8e-05 23.5 3.2 6.3e-05 22.7 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP16200.1 - 0.00011 22.2 4.5 0.0002 21.3 3.6 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEP16200.1 - 0.0012 18.6 3.8 0.0019 17.9 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4079 PF13301.6 CEP16200.1 - 0.0077 16.4 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) DUF2681 PF10883.8 CEP16200.1 - 0.012 16.0 0.1 0.019 15.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) zf-C3H2C3 PF17122.5 CEP16200.1 - 0.026 14.6 3.9 0.1 12.7 3.9 2.0 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 CEP16200.1 - 0.033 14.4 5.8 0.41 10.8 5.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CEP16200.1 - 0.066 12.8 5.7 0.044 13.4 4.0 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CEP16200.1 - 0.068 13.1 4.3 0.12 12.3 4.3 1.4 1 0 0 1 1 1 0 PHD-finger DDE_Tnp_ISAZ013 PF07592.11 CEP16200.1 - 0.093 11.7 0.0 3.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Endonuclease_7 PF02945.15 CEP16200.1 - 0.097 12.6 3.3 1.7 8.6 0.1 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII RINGv PF12906.7 CEP16200.1 - 0.15 12.2 3.9 0.41 10.8 3.8 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CEP16200.1 - 0.29 11.5 3.6 0.53 10.6 3.6 1.4 1 0 0 1 1 1 0 RING-like domain Vps39_2 PF10367.9 CEP16200.1 - 6.7 7.2 6.1 7.4 7.1 1.2 2.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Pkinase PF00069.25 CEP16201.1 - 2e-37 129.0 0.1 9.6e-35 120.2 0.1 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16201.1 - 3.9e-15 55.8 0.0 1.4e-10 40.9 0.0 4.0 1 1 0 1 1 1 1 Protein tyrosine kinase BTB PF00651.31 CEP16202.1 - 2.2e-16 60.1 2.1 2.7e-11 43.7 0.6 2.7 2 0 0 2 2 2 2 BTB/POZ domain CAP_GLY PF01302.25 CEP16202.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 CAP-Gly domain DUF4692 PF15763.5 CEP16203.1 - 0.12 12.8 1.9 0.12 12.8 1.9 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) UCH_1 PF13423.6 CEP16204.1 - 8.1e-98 327.9 2.3 1.1e-97 327.5 2.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CEP16204.1 - 1.8e-20 74.2 0.1 5.5e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 CEP16204.1 - 1e-11 44.9 0.1 1.7e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrome_C7 PF14522.6 CEP16204.1 - 0.16 12.0 0.5 0.41 10.7 0.5 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Acyltransferase PF01553.21 CEP16205.1 - 2.8e-05 23.8 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Y_phosphatase2 PF03162.13 CEP16206.1 - 1.7e-30 105.8 0.3 3.7e-30 104.7 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEP16206.1 - 0.036 14.1 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 CEP16206.1 - 0.044 13.3 2.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase CppA_C PF14507.6 CEP16206.1 - 0.095 13.4 0.2 0.2 12.4 0.2 1.5 1 0 0 1 1 1 0 CppA C-terminal Prothymosin PF03247.14 CEP16206.1 - 0.28 11.6 13.7 0.61 10.6 13.7 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family Macoilin PF09726.9 CEP16206.1 - 2.8 6.4 9.0 3.6 6.0 9.0 1.1 1 0 0 1 1 1 0 Macoilin family CDC73_C PF05179.14 CEP16207.1 - 3.5e-49 166.5 2.8 3.5e-49 166.5 2.8 2.0 3 0 0 3 3 3 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 CEP16207.1 - 2.4e-22 79.6 3.7 7.2e-18 64.9 0.7 2.5 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Helicase_IV_N PF12462.8 CEP16207.1 - 0.079 12.9 1.0 0.16 11.9 1.0 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DDE_3 PF13358.6 CEP16209.1 - 8.8e-26 90.4 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 CEP16209.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Integrase core domain MIT_LIKE_ACTX PF17556.2 CEP16210.1 - 0.093 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 MIT-like atracotoxin family NDC10_II PF16787.5 CEP16211.1 - 4.2e-07 29.3 1.9 0.0028 16.8 0.1 2.4 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ras PF00071.22 CEP16212.1 - 0.00091 18.9 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Ras family SUIM_assoc PF16619.5 CEP16214.1 - 0.19 11.8 18.7 0.28 11.3 0.2 4.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ECH_1 PF00378.20 CEP16215.1 - 2.3e-41 141.8 0.0 3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP16215.1 - 6.9e-13 48.8 0.0 8.2e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UQ_con PF00179.26 CEP16216.1 - 5.4e-45 152.5 0.0 1e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CEP16216.1 - 0.015 15.6 0.1 0.015 15.6 0.1 3.0 2 1 0 2 2 2 0 RWD domain Prok-E2_B PF14461.6 CEP16216.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B MFS_1 PF07690.16 CEP16217.1 - 6.9e-36 123.9 69.1 6.6e-27 94.4 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP16217.1 - 0.0012 17.8 12.2 0.0012 17.8 12.2 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 CEP16217.1 - 0.027 13.0 30.1 0.037 12.6 10.6 2.3 2 0 0 2 2 2 0 MFS/sugar transport protein Arm PF00514.23 CEP16218.1 - 6.5e-34 114.9 24.5 6.8e-07 29.1 0.4 11.3 11 0 0 11 11 11 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CEP16218.1 - 1.1e-19 68.9 20.2 0.032 14.5 0.2 9.7 11 0 0 11 11 10 6 HEAT repeat HEAT_2 PF13646.6 CEP16218.1 - 1.9e-16 60.2 9.1 0.0028 18.0 0.1 7.6 5 3 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 CEP16218.1 - 1.9e-10 41.0 20.6 0.16 12.5 0.1 8.9 9 0 0 9 9 9 4 HEAT-like repeat Cnd1 PF12717.7 CEP16218.1 - 1.7e-09 37.9 7.5 0.00014 22.0 0.2 4.4 2 2 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 CEP16218.1 - 7.6e-07 29.2 9.4 0.086 12.8 0.0 5.7 4 1 2 6 6 6 3 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 CEP16218.1 - 1.8e-06 28.5 2.5 0.5 11.0 0.1 4.7 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CEP16218.1 - 0.0041 17.3 5.4 0.72 10.1 0.0 5.4 5 2 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 CEP16218.1 - 0.012 15.6 4.0 3.9 7.6 0.0 5.0 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 CEP16218.1 - 0.1 13.0 5.4 40 4.7 0.1 5.2 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nipped-B_C PF12830.7 CEP16218.1 - 0.27 11.1 2.9 0.38 10.7 0.1 2.7 3 1 0 3 3 3 0 Sister chromatid cohesion C-terminus ATP-synt_C PF00137.21 CEP16219.1 - 2.2e-31 108.0 29.8 1.1e-18 67.3 12.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MBOAT PF03062.19 CEP16220.1 - 1.1e-37 130.2 17.8 5.3e-37 128.0 17.8 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAP PF00956.18 CEP16221.1 - 3.7e-97 324.7 6.6 3.7e-97 324.7 6.6 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 CEP16221.1 - 0.3 10.8 24.4 0.021 14.5 14.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 CEP16221.1 - 2.1 8.6 30.4 1.8 8.8 20.9 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Spc7 PF08317.11 CEP16224.1 - 0.023 13.6 31.6 0.18 10.7 14.1 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 CEP16224.1 - 0.031 14.4 37.5 0.25 11.4 15.5 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CEP16224.1 - 0.033 14.8 23.8 0.06 14.0 3.9 3.1 1 1 2 3 3 3 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 CEP16224.1 - 0.043 14.0 33.5 0.09 13.0 13.0 2.6 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Sulfatase PF00884.23 CEP16224.1 - 0.16 11.3 1.7 0.17 11.3 0.3 1.6 2 0 0 2 2 2 0 Sulfatase DUF3450 PF11932.8 CEP16224.1 - 0.51 9.6 32.6 0.62 9.3 11.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 CEP16224.1 - 1.5 9.2 12.7 8.1 6.9 1.3 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 CEP16224.1 - 1.8 8.4 32.2 45 3.8 32.3 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 CEP16224.1 - 2 8.6 20.0 2.5 8.3 0.2 4.0 3 1 1 4 4 4 0 bZIP transcription factor Cnn_1N PF07989.11 CEP16224.1 - 2.2 8.5 20.2 1.8 8.8 2.9 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 CEP16224.1 - 2.8 8.5 37.1 4.4 7.9 18.0 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region TSC22 PF01166.18 CEP16224.1 - 3.2 8.1 14.2 4.3 7.7 0.3 3.6 3 2 0 3 3 3 0 TSC-22/dip/bun family Fez1 PF06818.15 CEP16224.1 - 4.4 7.7 32.7 16 5.9 11.0 2.4 1 1 1 2 2 2 0 Fez1 HALZ PF02183.18 CEP16224.1 - 5.6 7.3 10.4 0.45 10.8 0.8 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF812 PF05667.11 CEP16224.1 - 6.7 5.5 30.1 18 4.1 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fzo_mitofusin PF04799.13 CEP16224.1 - 9.5 5.7 21.3 1 8.9 14.8 2.4 1 1 2 3 3 3 0 fzo-like conserved region rve PF00665.26 CEP16225.1 - 1.8e-19 70.1 0.0 4e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP16225.1 - 7.3e-13 48.4 1.1 1.5e-12 47.5 0.8 1.7 1 1 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP16225.1 - 0.0038 17.0 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CEP16225.1 - 0.01 16.0 0.2 0.042 14.1 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger DDE_3 PF13358.6 CEP16225.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 CEP16226.1 - 2.8e-24 85.0 0.0 4.4e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16226.1 - 1.2e-18 67.3 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pepsin-I3 PF06394.13 CEP16226.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain HTH_Tnp_Tc3_2 PF01498.18 CEP16228.1 - 8.2e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CEP16228.1 - 4.3e-07 29.8 1.5 6.7e-07 29.2 0.4 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease SpoIISB_antitox PF14185.6 CEP16229.1 - 0.022 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system CCP_MauG PF03150.14 CEP16230.1 - 0.065 13.9 0.0 0.073 13.7 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase YBD PF17725.1 CEP16231.1 - 0.011 15.6 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 YAP binding domain RVT_1 PF00078.27 CEP16232.1 - 1.3e-09 37.9 0.1 1.4e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP16232.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP16232.1 - 2.1e-06 28.2 0.0 5.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP16232.1 - 5.9e-06 26.1 0.2 1.2e-05 25.1 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CEP16232.1 - 0.016 15.0 0.1 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 CEP16232.1 - 0.031 14.3 1.1 0.074 13.2 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 CEP16232.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Tctex-1 PF03645.13 CEP16232.1 - 7.5 6.9 6.4 1 9.6 0.6 2.6 3 0 0 3 3 3 0 Tctex-1 family Retrotrans_gag PF03732.17 CEP16233.1 - 2.6e-06 27.6 0.0 1.8e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP16233.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apolipoprotein PF01442.18 CEP16233.1 - 0.03 14.2 1.5 0.047 13.6 1.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Spc19 PF08287.11 CEP16233.1 - 0.91 9.4 6.8 0.41 10.5 0.5 2.2 2 0 0 2 2 2 0 Spc19 RP-C_C PF11800.8 CEP16233.1 - 1.4 9.0 6.7 5.8 6.9 1.7 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region AAA_30 PF13604.6 CEP16234.1 - 1.9e-11 44.1 0.0 2.3e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 CEP16234.1 - 2.7e-10 40.0 0.0 3e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_22 PF13401.6 CEP16234.1 - 1.9e-05 25.0 0.1 0.00011 22.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP16234.1 - 2.2e-05 24.8 0.3 0.00013 22.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP16234.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CEP16234.1 - 0.0021 18.0 0.0 0.048 13.5 0.0 2.0 1 1 0 1 1 1 1 Helicase MeaB PF03308.16 CEP16234.1 - 0.0092 15.0 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 CEP16234.1 - 0.034 13.5 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TK PF00265.18 CEP16234.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase ABC_tran PF00005.27 CEP16234.1 - 0.067 13.7 0.2 0.12 12.8 0.1 1.5 2 0 0 2 2 2 0 ABC transporter DUF87 PF01935.17 CEP16234.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 CEP16234.1 - 0.078 13.4 0.0 0.2 12.0 0.0 1.5 1 1 1 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CEP16234.1 - 0.087 13.2 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CEP16234.1 - 0.097 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 CEP16234.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2791 PF10923.8 CEP16234.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) GBP PF02263.19 CEP16234.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA PF00004.29 CEP16234.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CEP16234.1 - 0.15 11.7 0.4 0.28 10.9 0.4 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CEP16234.1 - 0.21 10.8 0.1 0.39 9.9 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) FSA_C PF10479.9 CEP16235.1 - 0.026 12.7 0.4 0.026 12.7 0.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4609 PF15382.6 CEP16235.1 - 0.098 12.6 2.3 0.14 12.0 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4609) DUF4680 PF15730.5 CEP16236.1 - 0.033 14.5 0.6 0.037 14.4 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) LCE6A PF15858.5 CEP16236.1 - 0.072 13.8 0.8 0.082 13.7 0.8 1.1 1 0 0 1 1 1 0 Late cornified envelope protein 6A family TFIIF_alpha PF05793.12 CEP16236.1 - 0.44 9.1 10.6 0.5 8.9 10.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3439 PF11921.8 CEP16236.1 - 1.3 9.0 4.4 1.5 8.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Helitron_like_N PF14214.6 CEP16237.1 - 2.2e-27 96.5 0.1 7.9e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus UvrD_C_2 PF13538.6 CEP16237.1 - 4.2e-11 42.5 0.1 4.4e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP16237.1 - 4.5e-05 21.6 0.0 7e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CEP16237.1 - 0.00059 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 CEP16237.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase zf-CCHC_2 PF13696.6 CEP16238.1 - 0.11 12.3 1.1 0.2 11.5 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle HTH_Tnp_Tc5 PF03221.16 CEP16244.1 - 1.5e-09 37.7 0.0 4.4e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEP16244.1 - 1.3e-05 24.8 3.2 1.5e-05 24.6 1.8 1.8 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF2489 PF10675.9 CEP16245.1 - 0.15 11.9 3.3 0.92 9.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Phage_int_SAM_1 PF02899.17 CEP16246.1 - 0.013 15.7 1.6 0.031 14.6 0.5 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP16246.1 - 0.036 14.5 1.5 0.073 13.5 0.4 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RVT_1 PF00078.27 CEP16247.1 - 6e-15 55.4 0.4 1.5e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_1 PF02899.17 CEP16247.1 - 0.0018 18.6 0.5 0.0057 16.9 0.5 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain RNase_H PF00075.24 CEP16247.1 - 0.0049 17.1 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 RNase H Phage_integrase PF00589.22 CEP16247.1 - 0.013 15.3 0.0 0.047 13.5 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family RT_RNaseH_2 PF17919.1 CEP16247.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Phage_int_SAM_4 PF13495.6 CEP16247.1 - 0.12 12.8 0.1 0.4 11.2 0.1 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain TPT PF03151.16 CEP16248.1 - 3.9e-26 92.1 25.5 4.7e-26 91.8 25.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CEP16248.1 - 1.4e-09 38.2 38.9 8.3e-06 26.0 12.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP16248.1 - 0.0041 16.3 21.1 0.21 10.7 20.6 2.7 1 1 1 2 2 2 1 Nucleotide-sugar transporter Topoisom_bac PF01131.20 CEP16249.1 - 8.8e-106 354.4 0.0 1.1e-105 354.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CEP16249.1 - 5.4e-26 90.4 14.8 1.3e-13 50.8 1.0 2.8 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 CEP16249.1 - 7.3e-19 67.9 0.0 1.4e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Evr1_Alr PF04777.13 CEP16250.1 - 2.9e-21 75.8 0.1 4.1e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family zf-CCCH PF00642.24 CEP16251.1 - 4.9e-08 32.7 45.0 2.3e-05 24.2 1.0 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CEP16251.1 - 2.1e-07 31.1 21.0 0.00071 19.8 1.0 3.7 2 1 1 3 3 3 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 CEP16251.1 - 6.1e-07 29.3 47.4 0.00045 20.2 6.7 6.0 5 2 0 5 5 5 4 Zinc finger domain Torus PF16131.5 CEP16251.1 - 0.00018 22.2 36.2 0.00028 21.6 0.6 5.1 1 1 3 5 5 5 3 Torus domain zf-CCCH_4 PF18044.1 CEP16251.1 - 0.00033 20.4 4.0 0.00033 20.4 4.0 6.0 6 1 0 6 6 6 2 CCCH-type zinc finger TFIIA PF03153.13 CEP16251.1 - 1.6 8.6 32.5 3.1 7.7 32.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD_2 PF06733.15 CEP16251.1 - 3.6 7.2 9.7 0.068 12.8 1.8 2.0 2 1 0 2 2 2 0 DEAD_2 RVT_1 PF00078.27 CEP16252.1 - 3e-10 40.0 0.0 2e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) S10_plectin PF03501.15 CEP16253.1 - 3.5e-42 142.4 0.1 4.1e-42 142.2 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Kinase-like PF14531.6 CEP16253.1 - 0.0035 16.7 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF1495 PF07381.11 CEP16253.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) DUF4364 PF14277.6 CEP16253.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) TrmB PF01978.19 CEP16253.1 - 0.16 11.8 0.1 0.45 10.4 0.1 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 CEP16253.1 - 0.27 11.3 0.6 13 6.0 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) PIG-P PF08510.12 CEP16255.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 PIG-P Tma16 PF11176.8 CEP16255.1 - 0.16 11.9 3.9 0.26 11.2 3.9 1.3 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Ferritin PF00210.24 CEP16255.1 - 0.2 11.6 1.1 0.34 10.8 1.1 1.4 1 0 0 1 1 1 0 Ferritin-like domain Prefoldin PF02996.17 CEP16255.1 - 5.3 7.0 6.9 3.3 7.7 1.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit AMP-binding PF00501.28 CEP16256.1 - 1.5e-82 277.5 0.0 8.3e-54 182.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEP16256.1 - 1.1e-13 51.9 0.0 9e-13 49.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CEP16257.1 - 2e-53 181.6 50.6 2.3e-53 181.4 49.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CEP16257.1 - 9.6e-18 63.9 17.5 9.6e-18 63.9 17.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CEP16257.1 - 4e-14 52.3 7.8 4e-14 52.3 7.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 CEP16257.1 - 0.0011 18.0 8.3 0.0011 18.0 8.3 2.3 2 0 0 2 2 2 1 MFS_1 like family AAA_3 PF07726.11 CEP16257.1 - 0.043 13.7 0.1 0.62 9.9 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dirigent PF03018.14 CEP16257.1 - 1.3 8.8 4.2 23 4.7 0.3 3.0 2 1 1 3 3 3 0 Dirigent-like protein zf-C2H2 PF00096.26 CEP16258.1 - 3.5e-08 33.4 28.4 0.00025 21.3 5.3 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 CEP16258.1 - 6.5e-05 23.5 8.1 0.0015 19.1 0.3 3.5 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CEP16258.1 - 0.00075 19.8 10.2 0.0085 16.5 6.1 3.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP16258.1 - 0.014 16.2 3.6 0.014 16.2 3.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP16258.1 - 0.021 15.1 3.8 0.05 13.9 1.7 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP16258.1 - 0.05 14.0 4.2 2.1 8.8 1.7 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 CEP16258.1 - 0.52 10.5 0.0 0.52 10.5 0.0 3.0 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 CEP16258.1 - 6.3 6.9 10.8 0.11 12.5 2.6 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger Sld5 PF05916.11 CEP16259.1 - 0.07 13.6 2.3 0.099 13.1 0.3 2.3 2 0 0 2 2 2 0 GINS complex protein GAS PF13851.6 CEP16260.1 - 0.00058 19.3 0.8 0.00058 19.3 0.8 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding TBCC_N PF16752.5 CEP16260.1 - 0.001 19.5 2.3 0.001 19.5 2.3 2.0 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain TMF_DNA_bd PF12329.8 CEP16260.1 - 0.0034 17.3 2.0 0.0034 17.3 2.0 2.2 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Rogdi_lz PF10259.9 CEP16260.1 - 0.012 15.1 1.1 0.016 14.6 1.1 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein MtrB PF05440.12 CEP16260.1 - 0.013 15.9 0.1 0.033 14.6 0.1 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF948 PF06103.11 CEP16260.1 - 0.045 14.0 0.4 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 CEP16260.1 - 0.049 12.7 3.9 0.041 13.0 2.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 CEP16260.1 - 0.11 12.5 5.4 0.047 13.7 1.7 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 CEP16260.1 - 0.16 12.4 4.2 0.085 13.3 0.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Phage_HK97_TLTM PF06120.11 CEP16260.1 - 0.3 10.2 9.3 0.018 14.3 2.8 1.9 1 1 0 2 2 2 0 Tail length tape measure protein DivIC PF04977.15 CEP16260.1 - 0.33 10.7 4.2 1 9.2 3.7 2.1 1 1 0 1 1 1 0 Septum formation initiator THOC7 PF05615.13 CEP16260.1 - 0.41 10.9 8.7 0.37 11.1 3.3 2.7 2 1 0 2 2 2 0 Tho complex subunit 7 KinB_sensor PF16767.5 CEP16260.1 - 0.42 11.1 6.2 0.068 13.6 1.4 2.1 3 0 0 3 3 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Csm1_N PF18504.1 CEP16260.1 - 0.49 10.8 5.9 0.14 12.5 2.0 2.2 2 0 0 2 2 1 0 Csm1 N-terminal domain APG6_N PF17675.1 CEP16260.1 - 0.55 10.8 6.8 0.18 12.3 3.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 CEP16260.1 - 0.76 9.0 3.7 0.57 9.4 0.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein YabA PF06156.13 CEP16260.1 - 0.8 10.4 6.1 3.3 8.4 1.8 3.0 1 1 2 3 3 3 0 Initiation control protein YabA DivIVA PF05103.13 CEP16260.1 - 0.81 9.8 7.7 4.3 7.4 7.5 2.3 1 1 0 1 1 1 0 DivIVA protein Spc7 PF08317.11 CEP16260.1 - 0.87 8.4 8.6 1.1 8.1 6.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CEP16260.1 - 1 9.8 4.0 3.2 8.2 1.0 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 CEP16260.1 - 1.3 9.5 9.2 0.33 11.4 4.4 2.5 2 1 1 3 3 2 0 Cell division protein ZapB UPF0242 PF06785.11 CEP16260.1 - 2.2 8.4 9.2 0.42 10.7 2.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 CEP16260.1 - 3.1 8.0 20.2 0.15 12.2 9.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF3972 PF13118.6 CEP16260.1 - 5.4 7.5 9.9 0.21 12.0 2.0 2.5 3 1 0 3 3 2 0 Protein of unknown function (DUF3972) ubiquitin PF00240.23 CEP16261.1 - 0.0005 19.8 0.0 0.00093 18.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family DUF2457 PF10446.9 CEP16261.1 - 0.1 11.8 27.1 0.14 11.3 27.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GREB1 PF15782.5 CEP16261.1 - 0.14 9.3 6.1 0.15 9.2 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF936 PF06075.12 CEP16261.1 - 3.9 6.3 18.4 4.3 6.1 18.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Apt1 PF10351.9 CEP16261.1 - 4.7 6.0 19.2 6 5.6 19.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 CEP16263.1 - 5.6e-06 26.5 6.6 0.014 15.8 1.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP16263.1 - 0.0022 18.6 12.8 0.07 14.0 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP16263.1 - 0.0077 16.5 10.9 0.029 14.7 1.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CEP16263.1 - 0.018 15.3 4.4 0.043 14.1 4.4 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 CEP16263.1 - 0.045 13.8 0.1 0.045 13.8 0.1 3.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-met PF12874.7 CEP16263.1 - 0.062 13.7 2.2 0.33 11.4 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CEP16263.1 - 0.092 12.6 1.6 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 CEP16263.1 - 0.15 11.7 3.6 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CEP16263.1 - 0.28 11.5 5.2 0.43 10.9 0.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NUDIX PF00293.28 CEP16265.1 - 2.8e-15 56.5 0.5 3.6e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain NOG1_N PF17835.1 CEP16266.1 - 2e-56 190.4 2.4 5.1e-56 189.1 2.4 1.7 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CEP16266.1 - 1.2e-28 98.8 2.4 3.3e-28 97.4 2.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CEP16266.1 - 2.4e-28 97.6 2.0 3e-28 97.4 0.2 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CEP16266.1 - 7e-19 68.0 0.0 1.7e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP16266.1 - 5.3e-10 39.0 0.0 1.2e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEP16266.1 - 0.0002 21.3 0.1 0.29 11.0 0.0 3.1 2 2 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CEP16266.1 - 0.00075 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 CEP16266.1 - 0.0013 19.0 0.0 0.013 15.8 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CEP16266.1 - 0.0035 17.4 1.2 0.83 9.7 0.0 3.2 2 1 0 3 3 2 1 Dynamin family AAA_16 PF13191.6 CEP16266.1 - 0.0037 17.7 0.0 0.023 15.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 CEP16266.1 - 0.0071 15.9 0.3 0.35 10.4 0.2 3.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Beta-lactamase2 PF13354.6 CEP16266.1 - 0.048 13.3 3.2 0.18 11.4 0.7 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family TniB PF05621.11 CEP16266.1 - 0.06 12.8 0.1 0.5 9.8 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 CEP16266.1 - 0.22 10.7 4.1 0.7 9.0 0.2 2.9 2 1 0 3 3 3 0 G-protein alpha subunit Herpes_UL17 PF04559.12 CEP16266.1 - 3.5 6.3 5.5 5.4 5.7 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein RhoGAP PF00620.27 CEP16267.1 - 2.7e-30 105.2 0.0 1.9e-29 102.5 0.0 2.3 1 1 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CEP16267.1 - 6.1e-22 77.6 54.7 9.9e-10 38.5 7.0 5.0 5 0 0 5 5 5 4 LIM domain TFIIA PF03153.13 CEP16267.1 - 1.3 9.0 22.9 0.056 13.4 16.0 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP-synt_G PF04718.15 CEP16267.1 - 5.6 7.8 5.7 21 6.0 5.7 2.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit zf-RVT PF13966.6 CEP16268.1 - 3.3e-06 27.7 0.6 3.3e-06 27.7 0.6 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FAT PF02259.23 CEP16269.1 - 2.1e-124 415.2 0.4 5.7e-124 413.8 0.4 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CEP16269.1 - 6.8e-72 242.3 0.2 1.2e-71 241.5 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CEP16269.1 - 1.5e-65 220.0 7.1 1.5e-60 203.7 0.2 5.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CEP16269.1 - 1.1e-45 154.0 1.6 1.1e-45 154.0 1.6 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CEP16269.1 - 2.4e-16 59.3 1.1 7.9e-16 57.6 1.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CEP16269.1 - 3e-13 48.8 17.5 0.00065 19.7 0.0 10.7 12 0 0 12 12 8 2 HEAT repeat HEAT_2 PF13646.6 CEP16269.1 - 3.4e-12 46.6 9.1 0.018 15.4 0.0 9.5 6 3 3 10 10 9 3 HEAT repeats HEAT_EZ PF13513.6 CEP16269.1 - 2.8e-09 37.3 23.8 1.2e-05 25.6 0.2 9.3 10 1 1 11 11 8 3 HEAT-like repeat TPR_19 PF14559.6 CEP16269.1 - 1.9e-06 28.3 1.5 0.059 13.9 0.2 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Adaptin_N PF01602.20 CEP16269.1 - 1.3e-05 24.0 9.7 0.11 11.0 0.7 5.8 4 2 0 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.7 CEP16269.1 - 1.6e-05 25.0 3.0 0.015 15.3 0.1 5.3 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TPR_16 PF13432.6 CEP16269.1 - 2.1e-05 25.0 6.9 0.06 14.0 1.6 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 CEP16269.1 - 4.5e-05 24.0 7.2 22 5.7 0.0 7.7 7 2 1 8 8 7 0 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.14 CEP16269.1 - 0.00028 20.3 3.4 2 7.6 0.0 3.9 4 0 0 4 4 4 2 V-ATPase subunit H Tti2 PF10521.9 CEP16269.1 - 0.00056 19.5 7.0 0.27 10.8 0.1 5.2 3 1 2 5 5 5 1 Tti2 family MMS19_C PF12460.8 CEP16269.1 - 0.002 17.3 6.6 0.47 9.5 0.2 4.2 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Sec7_N PF12783.7 CEP16269.1 - 0.0026 17.7 0.3 0.45 10.4 0.0 4.7 4 1 0 4 4 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal IFRD PF05004.13 CEP16269.1 - 0.0074 15.4 0.6 1.8 7.6 0.0 4.3 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) ANAPC3 PF12895.7 CEP16269.1 - 0.014 15.6 1.0 2.6 8.3 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CEP16269.1 - 0.033 14.3 5.8 13 6.2 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP16269.1 - 0.053 13.8 3.1 8.3 6.8 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEP16269.1 - 0.18 11.8 1.6 0.8 9.7 0.3 2.7 3 0 0 3 3 2 0 Putative TPR-like repeat TPR_7 PF13176.6 CEP16269.1 - 0.22 11.6 2.9 6.7 7.0 0.2 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat KCH PF16944.5 CEP16270.1 - 1.9e-77 260.5 13.7 2.3e-77 260.2 13.7 1.1 1 0 0 1 1 1 1 Fungal potassium channel Ras PF00071.22 CEP16271.1 - 7.9e-42 142.6 0.1 1.2e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP16271.1 - 8.2e-20 71.2 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP16271.1 - 1.2e-08 34.6 0.3 1.7e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP16271.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ribosomal_S2 PF00318.20 CEP16272.1 - 4.3e-26 91.5 0.4 4.4e-13 49.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CEP16272.1 - 7.2e-05 24.1 19.6 0.00018 22.8 19.6 1.7 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_L27e PF01777.18 CEP16273.1 - 4e-37 126.4 7.1 4e-37 126.4 7.1 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 CEP16273.1 - 0.0027 17.6 6.5 0.0071 16.3 6.5 2.0 1 1 0 1 1 1 1 KOW motif PP1_bind PF15276.6 CEP16274.1 - 0.049 14.0 0.6 0.52 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein phosphatase 1 binding DDE_3 PF13358.6 CEP16277.1 - 1.8e-19 70.0 0.1 7.5e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP16277.1 - 9.9e-05 22.0 0.1 0.0002 21.1 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP16277.1 - 0.0028 17.8 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain rve PF00665.26 CEP16277.1 - 0.018 15.2 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain RBR PF17208.3 CEP16277.1 - 0.02 15.6 0.3 0.02 15.6 0.3 2.5 3 0 0 3 3 3 0 RNA binding Region HTH_29 PF13551.6 CEP16277.1 - 0.11 12.5 1.3 0.3 11.1 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix PDCD2_C PF04194.13 CEP16280.1 - 7.5e-42 143.4 10.7 5.7e-41 140.5 1.4 3.1 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain VHL PF01847.16 CEP16280.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 VHL beta domain YtxH PF12732.7 CEP16281.1 - 0.00023 21.6 28.1 3.5 8.2 13.2 3.8 1 1 1 2 2 2 1 YtxH-like protein Apolipoprotein PF01442.18 CEP16281.1 - 0.00044 20.2 16.2 0.002 18.0 16.2 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CEP16281.1 - 0.00045 20.8 19.0 0.023 15.3 2.7 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 CEP16281.1 - 0.0029 17.8 16.3 0.25 11.6 2.1 3.3 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF948) EFG_IV PF03764.18 CEP16281.1 - 0.047 13.5 3.7 3.8 7.3 0.4 3.4 1 1 2 3 3 3 0 Elongation factor G, domain IV PRKCSH-like PF12999.7 CEP16281.1 - 0.057 13.2 14.5 0.065 13.0 2.3 3.1 1 1 2 3 3 3 0 Glucosidase II beta subunit-like ApoLp-III PF07464.11 CEP16281.1 - 0.062 13.4 22.9 0.17 12.0 10.6 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CdvA PF18822.1 CEP16281.1 - 0.11 12.3 17.3 1.1 9.1 1.0 3.8 1 1 3 4 4 4 0 CdvA-like coiled-coil domain Seryl_tRNA_N PF02403.22 CEP16281.1 - 0.15 12.3 24.4 0.84 9.9 7.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 CEP16281.1 - 0.62 8.9 6.1 0.71 8.7 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Dynein_light PF01221.18 CEP16281.1 - 0.92 9.9 13.3 1.9 8.9 0.9 3.9 3 1 1 4 4 4 0 Dynein light chain type 1 Peptidase_M3_N PF08439.10 CEP16281.1 - 1 9.7 6.1 0.38 11.1 0.6 2.5 2 0 0 2 2 2 0 Oligopeptidase F DUF4047 PF13256.6 CEP16281.1 - 1.7 8.9 8.6 0.51 10.5 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) TMPIT PF07851.13 CEP16281.1 - 2.1 7.5 15.3 1.5 8.0 5.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 CEP16281.1 - 2.1 8.4 11.6 2.9 7.9 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ndc1_Nup PF09531.10 CEP16281.1 - 2.1 6.9 7.6 2.1 6.9 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LEA_4 PF02987.16 CEP16281.1 - 2.3 8.3 25.4 1.4 9.1 2.1 5.3 3 2 1 4 4 4 0 Late embryogenesis abundant protein TMP_2 PF06791.13 CEP16281.1 - 3.3 7.3 14.4 0.45 10.2 6.8 2.3 1 1 2 3 3 3 0 Prophage tail length tape measure protein ApoO PF09769.9 CEP16281.1 - 3.7 7.5 7.3 11 6.0 1.1 3.0 1 1 2 3 3 3 0 Apolipoprotein O Atg14 PF10186.9 CEP16281.1 - 4.6 6.2 11.0 6.5 5.7 11.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CBFD_NFYB_HMF PF00808.23 CEP16281.1 - 4.7 7.6 7.5 1.1 9.6 0.9 3.1 2 2 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fib_alpha PF08702.10 CEP16281.1 - 5.1 7.3 10.6 2.6 8.3 3.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GCN5L1 PF06320.13 CEP16281.1 - 6.3 7.0 17.4 1.3 9.1 6.2 2.9 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1674 PF07896.12 CEP16282.1 - 5.5e-19 68.4 2.9 9.1e-19 67.7 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MBOAT PF03062.19 CEP16283.1 - 1.1e-23 84.2 17.0 1.5e-23 83.8 17.0 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Adipogenin PF15202.6 CEP16283.1 - 0.68 10.0 0.0 0.68 10.0 0.0 2.7 3 0 0 3 3 3 0 Adipogenin ACOX PF01756.19 CEP16284.1 - 1.4e-36 125.8 0.0 3.8e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CEP16284.1 - 2.9e-20 73.1 0.2 6e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CEP16284.1 - 1.3e-09 38.1 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP16284.1 - 0.0011 19.2 0.2 0.059 13.6 0.0 3.7 4 1 0 4 4 4 1 Acyl-CoA dehydrogenase, C-terminal domain E3_UbLigase_EDD PF11547.8 CEP16284.1 - 0.12 12.1 0.2 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 E3 ubiquitin ligase EDD CBM_5_12 PF02839.14 CEP16284.1 - 0.19 12.4 0.6 0.66 10.7 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain Nuc_sug_transp PF04142.15 CEP16285.1 - 8.4e-06 25.2 0.7 2.7e-05 23.5 0.7 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CEP16285.1 - 0.04 14.1 23.5 0.26 11.4 6.3 3.2 3 0 0 3 3 3 0 EamA-like transporter family DUF3810 PF12725.7 CEP16285.1 - 0.058 12.7 1.9 0.22 10.8 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) PrgI PF12666.7 CEP16285.1 - 9.7 7.0 7.7 4.6 8.0 0.2 3.0 3 0 0 3 3 3 0 PrgI family protein Cyt-b5 PF00173.28 CEP16286.1 - 1.8e-23 82.4 0.1 2.6e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gln-synt_C PF00120.24 CEP16287.1 - 3.2e-79 266.5 0.0 3.8e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain UDPGP PF01704.18 CEP16288.1 - 4.8e-55 186.9 0.0 6.2e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CEP16288.1 - 0.021 15.2 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain RasGEF PF00617.19 CEP16289.1 - 5.8e-37 127.6 3.9 5.8e-37 127.6 3.9 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CEP16289.1 - 6.8e-16 58.4 0.2 6.8e-16 58.4 0.2 3.9 4 0 0 4 4 4 1 RasGEF N-terminal motif NRN1 PF15056.6 CEP16289.1 - 0.1 12.7 0.5 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Neuritin protein family Shugoshin_C PF07557.11 CEP16290.1 - 0.00066 19.4 1.4 0.00066 19.4 1.4 1.8 2 0 0 2 2 2 1 Shugoshin C terminus Nucleotid_trans PF03407.16 CEP16291.1 - 4.1e-10 40.0 0.1 6.3e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-C2H2_4 PF13894.6 CEP16293.1 - 0.019 15.7 0.4 0.071 14.0 0.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP16293.1 - 0.038 14.4 0.4 0.12 12.9 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 CEP16293.1 - 0.078 13.4 0.4 0.23 11.9 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP16293.1 - 0.26 11.6 0.2 0.26 11.6 0.2 2.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PBP1_TM PF14812.6 CEP16294.1 - 0.031 14.6 0.4 0.038 14.4 0.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_IS1595 PF12762.7 CEP16296.1 - 1.7e-16 60.6 0.2 3.3e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain CENP-B_dimeris PF09026.10 CEP16297.1 - 0.029 14.8 8.3 0.055 13.9 8.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CEP16297.1 - 3 7.5 7.6 4.5 6.9 7.6 1.2 1 0 0 1 1 1 0 FAM176 family zf-TFIIB PF13453.6 CEP16297.1 - 3.4 7.1 5.1 0.93 8.9 0.3 2.3 3 0 0 3 3 3 0 Transcription factor zinc-finger Enterotoxin_b PF01376.18 CEP16298.1 - 0.035 14.3 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain Transcrip_act PF04949.13 CEP16298.1 - 0.076 12.9 0.0 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Transcriptional activator DNA_pol_phi PF04931.13 CEP16300.1 - 0.32 9.1 22.9 0.29 9.2 22.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 CEP16300.1 - 0.56 9.6 14.1 0.63 9.4 14.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 CEP16300.1 - 0.56 10.2 10.6 0.67 10.0 10.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PTPRCAP PF15713.5 CEP16300.1 - 1.1 9.5 14.0 1.3 9.3 14.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Vfa1 PF08432.10 CEP16300.1 - 1.4 9.3 9.2 1.6 9.1 9.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 CEP16300.1 - 1.7 8.0 15.2 1.8 7.9 15.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Paf1 PF03985.13 CEP16300.1 - 2.2 7.2 14.6 2.6 6.9 14.6 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 CEP16300.1 - 2.5 6.3 15.1 2.5 6.3 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 CEP16300.1 - 2.6 7.8 14.7 2.6 7.7 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TFB6 PF17110.5 CEP16300.1 - 2.6 7.7 10.0 2.9 7.6 10.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 CEP16300.1 - 2.7 7.4 20.0 2.9 7.2 20.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CEP16300.1 - 4.7 5.3 20.2 4.6 5.3 20.2 1.0 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 CEP16300.1 - 4.9 7.0 10.2 5.5 6.9 10.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 CEP16300.1 - 5.4 6.3 15.9 5.6 6.2 15.9 1.0 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 CEP16300.1 - 6 5.9 25.3 6.4 5.8 25.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.11 CEP16300.1 - 7.5 6.1 17.4 7.4 6.1 17.4 1.1 1 0 0 1 1 1 0 PPP4R2 AAA PF00004.29 CEP16301.1 - 1.3e-82 274.8 0.0 2.7e-40 137.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP16301.1 - 3.5e-28 97.1 0.2 1.2e-13 50.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEP16301.1 - 5.2e-14 53.0 0.2 0.00044 20.7 0.0 3.7 2 2 0 3 3 3 3 AAA ATPase domain AAA_5 PF07728.14 CEP16301.1 - 3.2e-11 43.4 0.1 7e-06 26.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP16301.1 - 1.2e-10 41.3 0.0 0.00057 19.7 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Kdo PF06293.14 CEP16301.1 - 7.8e-09 35.2 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_2 PF07724.14 CEP16301.1 - 8.3e-09 35.8 0.0 0.00046 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Pkinase PF00069.25 CEP16301.1 - 1e-08 34.9 0.1 1.8e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA_14 PF13173.6 CEP16301.1 - 7e-08 32.6 0.0 0.00051 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CEP16301.1 - 7.2e-08 32.0 0.2 0.017 14.4 0.1 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CEP16301.1 - 2.9e-07 30.8 1.1 0.73 10.1 0.0 3.9 2 2 2 4 4 3 2 AAA domain NTPase_1 PF03266.15 CEP16301.1 - 1.4e-06 28.3 0.0 0.041 13.8 0.0 3.4 3 0 0 3 3 3 2 NTPase APH PF01636.23 CEP16301.1 - 2.1e-06 27.8 0.0 1.6e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RNA_helicase PF00910.22 CEP16301.1 - 2.5e-06 27.9 0.0 0.043 14.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 CEP16301.1 - 3.8e-06 27.0 0.1 0.0011 18.9 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain Pkinase_Tyr PF07714.17 CEP16301.1 - 7e-06 25.5 0.1 1.2e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_3 PF07726.11 CEP16301.1 - 9.2e-06 25.5 0.0 0.032 14.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RIO1 PF01163.22 CEP16301.1 - 9.4e-06 25.4 0.0 2.6e-05 23.9 0.0 1.7 2 0 0 2 2 1 1 RIO1 family AAA_25 PF13481.6 CEP16301.1 - 9.8e-06 25.3 0.6 0.042 13.4 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP16301.1 - 1.2e-05 25.5 0.0 0.007 16.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CEP16301.1 - 2.5e-05 23.9 0.0 0.025 14.1 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CEP16301.1 - 6e-05 23.1 0.7 0.64 9.9 0.1 3.5 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEP16301.1 - 6.5e-05 23.5 0.0 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CEP16301.1 - 0.00011 22.2 0.1 0.21 11.5 0.1 3.2 2 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 CEP16301.1 - 0.00012 22.0 0.0 0.37 10.8 0.0 3.0 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CEP16301.1 - 0.0002 21.8 0.0 0.69 10.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 CEP16301.1 - 0.00051 20.5 0.1 0.32 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEP16301.1 - 0.00077 19.2 0.1 0.048 13.4 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CEP16301.1 - 0.0015 18.3 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 CEP16301.1 - 0.0017 17.3 0.0 0.083 11.8 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase AAA_11 PF13086.6 CEP16301.1 - 0.0018 18.1 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEP16301.1 - 0.0025 17.0 0.0 0.74 9.0 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain Choline_kinase PF01633.20 CEP16301.1 - 0.0031 17.1 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Mg_chelatase PF01078.21 CEP16301.1 - 0.0043 16.5 0.2 2 7.8 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CEP16301.1 - 0.0043 16.2 0.0 0.82 8.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) EcKinase PF02958.20 CEP16301.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Bac_DnaA PF00308.18 CEP16301.1 - 0.0082 16.0 0.0 0.39 10.5 0.0 3.0 2 1 0 2 2 2 1 Bacterial dnaA protein KAP_NTPase PF07693.14 CEP16301.1 - 0.0089 15.3 0.0 4.8 6.3 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain RsgA_GTPase PF03193.16 CEP16301.1 - 0.014 15.3 0.0 0.96 9.3 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 CEP16301.1 - 0.017 14.8 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEP16301.1 - 0.027 14.7 0.1 6.4 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CEP16301.1 - 0.029 14.7 0.2 4.7 7.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain WaaY PF06176.11 CEP16301.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Viral_helicase1 PF01443.18 CEP16301.1 - 0.082 12.6 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MCM PF00493.23 CEP16301.1 - 0.1 11.7 0.0 11 5.0 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Zeta_toxin PF06414.12 CEP16301.1 - 0.16 11.2 0.0 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Med7 PF05983.11 CEP16302.1 - 4.3e-54 183.5 2.6 5e-54 183.3 2.6 1.1 1 0 0 1 1 1 1 MED7 protein Ribonuclease_3 PF00636.26 CEP16303.1 - 0.0022 18.6 0.5 0.0052 17.4 0.4 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CEP16303.1 - 0.02 15.1 0.9 0.17 12.1 0.9 2.2 1 1 0 1 1 1 0 Ribonuclease-III-like ACT_7 PF13840.6 CEP16307.1 - 2.1e-24 85.0 0.0 7.2e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 ACT domain RicinB_lectin_2 PF14200.6 CEP16308.1 - 2.3e-21 76.3 3.6 1.5e-09 38.5 0.1 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CEP16308.1 - 3.8e-16 59.5 0.0 1.4e-09 38.2 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain CFAP91 PF14738.6 CEP16308.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 Motile_Sperm PF00635.26 CEP16310.1 - 1.4e-16 60.3 0.3 1.7e-16 60.0 0.3 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Arrestin_C PF02752.22 CEP16311.1 - 9.5e-10 39.0 1.1 7.5e-08 32.9 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP16311.1 - 1.5e-06 28.3 0.0 3.6e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP16311.1 - 0.00034 20.4 0.1 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Pkinase PF00069.25 CEP16312.1 - 1.1e-47 162.6 0.0 1.7e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16312.1 - 3.2e-23 82.4 0.0 4.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP16312.1 - 0.00026 21.0 0.0 0.00067 19.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP16312.1 - 0.0059 16.0 0.0 0.017 14.4 0.1 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CEP16312.1 - 0.023 14.4 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SRI PF08236.11 CEP16312.1 - 0.031 14.4 0.0 20 5.4 0.0 3.1 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Rxt3 PF08642.10 CEP16313.1 - 3.2e-26 92.6 0.1 3.2e-26 92.6 0.1 3.6 4 1 0 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CEP16313.1 - 2.2e-05 24.5 0.0 0.0026 17.8 0.0 3.0 1 1 0 1 1 1 1 LCCL domain Ribosomal_L28e PF01778.17 CEP16314.1 - 1.2e-41 142.1 1.9 1.2e-41 142.1 1.9 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CEP16314.1 - 2.1e-29 102.0 21.2 2.1e-29 102.0 21.2 1.9 3 0 0 3 3 3 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 CEP16314.1 - 0.09 12.5 1.4 0.15 11.8 1.4 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain RVP_2 PF08284.11 CEP16316.1 - 8e-08 32.1 0.2 1.7e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP16316.1 - 5.1e-07 30.3 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP16316.1 - 6.5e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CEP16316.1 - 5.2e-05 22.9 0.1 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase DUF4939 PF16297.5 CEP16316.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_5 PF14787.6 CEP16316.1 - 0.049 13.3 0.3 0.049 13.3 0.3 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Velvet PF11754.8 CEP16317.1 - 8e-24 84.9 3.2 1.2e-13 51.6 0.3 5.1 2 2 2 4 4 4 3 Velvet factor RNA_pol_Rpc4 PF05132.14 CEP16317.1 - 0.024 15.1 1.1 0.055 13.9 1.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Acetyltransf_1 PF00583.25 CEP16318.1 - 1.7e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP16318.1 - 2.2e-06 28.0 0.0 4.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP16318.1 - 3.8e-05 23.6 0.0 9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBF PF03914.17 CEP16319.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 CBF/Mak21 family FSA_C PF10479.9 CEP16321.1 - 1.6 6.8 19.8 2.1 6.4 19.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NST1 PF13945.6 CEP16321.1 - 4 7.5 7.8 9.2 6.3 7.8 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIA PF03153.13 CEP16321.1 - 5.3 6.9 14.8 7.6 6.4 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 CEP16321.1 - 9.1 4.2 16.1 12 3.9 16.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDE_3 PF13358.6 CEP16322.1 - 7.1e-05 22.6 0.0 9.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2292 PF10055.9 CEP16322.1 - 0.39 10.4 2.9 0.33 10.6 1.1 1.8 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Mito_carr PF00153.27 CEP16323.1 - 3e-62 206.6 1.0 4.3e-22 77.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP16323.1 - 0.023 13.9 1.1 1.1 8.3 0.1 2.8 1 1 2 3 3 3 0 Gammaproteobacterial serine protease NAD_binding_2 PF03446.15 CEP16324.1 - 1.3e-43 148.9 0.4 1.9e-43 148.4 0.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CEP16324.1 - 4.8e-30 104.3 0.0 8e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CEP16324.1 - 4.8e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CEP16324.1 - 6.1e-05 23.0 1.1 0.0013 18.6 1.1 2.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CEP16324.1 - 0.00092 18.8 1.4 0.23 11.0 0.3 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 CEP16324.1 - 0.0012 19.3 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 CEP16324.1 - 0.0035 17.6 0.0 0.008 16.4 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 CEP16324.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 CEP16324.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Rossmann-like PF10727.9 CEP16324.1 - 0.015 15.2 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.12 CEP16324.1 - 0.027 14.0 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 CEP16324.1 - 0.098 12.0 0.2 0.18 11.2 0.1 1.7 1 1 0 1 1 1 0 ThiF family CoA_binding PF02629.19 CEP16324.1 - 0.16 12.7 0.5 0.48 11.1 0.1 2.0 2 0 0 2 2 2 0 CoA binding domain CAP-ZIP_m PF15255.6 CEP16324.1 - 0.2 11.9 0.2 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region SWIM PF04434.17 CEP16325.1 - 0.003 17.2 0.1 0.0054 16.4 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger WHIM1 PF15612.6 CEP16326.1 - 7.9e-05 22.1 0.1 0.00015 21.2 0.1 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 CEP16326.1 - 0.16 12.5 1.3 1.3 9.6 1.3 2.3 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PVL_ORF50 PF07768.11 CEP16326.1 - 2 8.7 5.3 1 9.7 2.2 1.9 1 1 1 2 2 2 0 PVL ORF-50-like family PBP1_TM PF14812.6 CEP16326.1 - 8.7 6.8 9.2 3.5 8.1 3.2 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EMP70 PF02990.16 CEP16327.1 - 2.6e-153 511.5 16.5 3.6e-153 511.0 16.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 EVC2_like PF12297.8 CEP16327.1 - 0.84 8.2 2.2 31 3.1 0.0 2.1 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Tmemb_18A PF09771.9 CEP16327.1 - 7.5 7.0 6.4 82 3.6 3.3 3.2 2 1 0 2 2 2 0 Transmembrane protein 188 OPT PF03169.15 CEP16328.1 - 4.1e-184 613.7 57.5 5e-184 613.4 57.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4441 PF14536.6 CEP16329.1 - 0.028 14.6 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Cytochrom_C_2 PF01322.20 CEP16329.1 - 0.15 13.0 0.1 0.28 12.1 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C' I-set PF07679.16 CEP16331.1 - 0.00039 20.4 0.0 32 4.7 0.0 5.1 5 0 0 5 5 5 3 Immunoglobulin I-set domain Na_Ca_ex PF01699.24 CEP16332.1 - 2.2e-36 125.1 48.2 1.4e-20 73.8 17.4 2.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Sdh_cyt PF01127.22 CEP16332.1 - 7.5 6.6 17.1 2.6 8.1 4.4 3.5 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF244 PF03112.14 CEP16333.1 - 0.075 12.9 0.8 0.22 11.4 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF KKLCAg1 PF15204.6 CEP16334.1 - 0.013 15.6 0.9 0.037 14.1 0.9 1.7 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 DUF244 PF03112.14 CEP16335.1 - 0.075 12.9 0.8 0.22 11.4 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DAO PF01266.24 CEP16337.1 - 4.7e-22 79.1 0.0 2.8e-10 40.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP16337.1 - 0.0075 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP16337.1 - 0.02 15.5 0.1 0.1 13.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP16337.1 - 0.036 14.3 0.2 0.1 12.8 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_2 PF02230.16 CEP16337.1 - 0.05 13.4 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FAD_binding_2 PF00890.24 CEP16337.1 - 0.08 12.0 0.7 0.11 11.6 0.1 1.4 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 CEP16337.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Aa_trans PF01490.18 CEP16339.1 - 4.2e-81 272.8 35.6 5.3e-81 272.4 35.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YbgT_YccB PF08173.11 CEP16340.1 - 0.015 15.4 1.1 0.015 15.4 1.1 2.8 3 0 0 3 3 3 0 Membrane bound YbgT-like protein DHQ_synthase PF01761.20 CEP16341.1 - 3.9e-93 311.4 0.0 5.9e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CEP16341.1 - 4e-44 151.6 0.0 1.6e-43 149.6 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase Fe-ADH_2 PF13685.6 CEP16341.1 - 1.9e-05 24.5 0.0 5.3e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase NmrA PF05368.13 CEP16341.1 - 0.035 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family DUF1688 PF07958.11 CEP16341.1 - 0.046 12.4 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) NdhM PF10664.9 CEP16341.1 - 0.14 12.5 0.0 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M RVT_1 PF00078.27 CEP16342.1 - 4.3e-17 62.4 0.4 5.4e-17 62.0 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.6 CEP16343.1 - 0.027 14.4 1.1 0.056 13.4 1.0 1.5 1 1 0 1 1 1 0 FlxA-like protein CCDC-167 PF15188.6 CEP16343.1 - 0.031 14.6 0.1 0.05 13.9 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_S7e PF01251.18 CEP16343.1 - 0.04 13.7 0.5 0.09 12.5 0.4 1.7 1 1 1 2 2 2 0 Ribosomal protein S7e DUF5610 PF18433.1 CEP16343.1 - 0.062 13.8 0.5 0.13 12.8 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5610) MbeB_N PF04837.12 CEP16343.1 - 0.12 12.7 2.2 1.6 9.1 0.8 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Caskin-tail PF16632.5 CEP16343.1 - 0.3 11.5 2.0 1 9.8 2.0 1.9 1 1 0 1 1 1 0 C-terminal region of Caskin Pkinase PF00069.25 CEP16344.1 - 3e-48 164.5 0.0 5.9e-41 140.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16344.1 - 5.6e-15 55.3 0.0 4.4e-13 49.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP16344.1 - 0.0028 17.0 0.0 0.0069 15.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP16344.1 - 0.0037 16.1 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEP16344.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 CEP16345.1 - 1.2e-11 44.3 1.9 3e-11 43.0 1.4 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 CEP16345.1 - 1.2e-09 38.7 9.6 0.00011 22.9 0.8 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 CEP16345.1 - 1.6e-05 24.7 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CEP16345.1 - 0.083 12.8 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box RAB3GAP2_N PF14655.6 CEP16345.1 - 0.099 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rieske_2 PF13806.6 CEP16345.1 - 0.11 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Rieske-like [2Fe-2S] domain Elongin_A PF06881.11 CEP16345.1 - 1.2 9.7 3.4 0.71 10.4 0.9 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PH PF00169.29 CEP16346.1 - 1.5e-20 73.7 1.1 3.6e-20 72.4 1.1 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 CEP16346.1 - 3.1e-15 56.0 0.0 7.8e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CEP16346.1 - 1.7e-13 50.2 0.1 5e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SAM_1 PF00536.30 CEP16346.1 - 4e-12 46.4 0.1 1.1e-11 45.0 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 CEP16346.1 - 2e-11 43.3 0.3 5e-11 42.0 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP16346.1 - 9.2e-09 34.9 0.2 1.7e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 CEP16346.1 - 9.4e-06 26.0 5.0 9.4e-06 26.0 5.0 4.1 4 1 0 4 4 3 1 Pleckstrin homology domain SAM_Ste50p PF09235.10 CEP16346.1 - 0.0019 18.4 0.1 0.0048 17.1 0.1 1.7 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_8 PF15409.6 CEP16346.1 - 0.0023 18.1 0.5 0.0094 16.2 0.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.16 CEP16346.1 - 0.0036 17.2 0.2 0.043 13.8 0.0 2.3 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CEP16346.1 - 0.0049 16.6 0.1 0.035 13.9 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_3 PF14593.6 CEP16346.1 - 0.017 15.2 0.4 0.04 14.0 0.4 1.6 1 0 0 1 1 1 0 PH domain PfkB PF00294.24 CEP16347.1 - 4.5e-59 200.2 0.2 5.3e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CEP16347.1 - 0.079 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase NB-ARC PF00931.22 CEP16347.1 - 0.19 10.9 0.1 0.44 9.7 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain HMA PF00403.26 CEP16348.1 - 5.5e-60 199.7 0.4 7.9e-15 55.1 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CEP16348.1 - 4.4e-41 140.4 4.4 4.4e-41 140.4 4.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEP16348.1 - 2e-35 123.0 1.7 3.5e-34 118.9 1.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP16348.1 - 0.0015 18.3 2.6 0.02 14.6 1.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 CEP16348.1 - 0.024 14.8 2.2 9.2 6.5 0.1 3.5 2 1 1 3 3 3 0 Papain fold toxin 2 Fer2_BFD PF04324.15 CEP16348.1 - 0.031 14.6 7.8 9.2 6.7 0.1 4.6 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain HAD PF12710.7 CEP16348.1 - 0.052 14.0 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase E6 PF00518.17 CEP16348.1 - 2.8 8.4 4.4 2.6 8.5 0.1 3.1 4 0 0 4 4 4 0 Early Protein (E6) Rad52_Rad22 PF04098.15 CEP16350.1 - 2.5e-48 163.9 1.1 7.9e-48 162.2 0.0 2.0 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 CEP16350.1 - 0.027 14.5 17.4 0.033 14.2 17.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phyto-Amp PF15438.6 CEP16350.1 - 0.059 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma F-protein PF00469.20 CEP16350.1 - 0.11 12.1 1.4 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef GTA_holin_3TM PF11351.8 CEP16350.1 - 0.83 10.2 6.4 1.6 9.3 6.4 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release WD40 PF00400.32 CEP16351.1 - 4e-10 40.1 23.1 0.0058 17.4 0.6 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CEP16351.1 - 7.2e-09 35.1 18.2 7.2e-09 35.1 18.2 2.6 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 CEP16351.1 - 0.0059 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 RWD domain zinc_ribbon_16 PF17034.5 CEP16351.1 - 0.025 14.8 18.8 0.25 11.5 19.0 2.4 1 1 1 2 2 2 0 Zinc-ribbon like family zinc_ribbon_2 PF13240.6 CEP16351.1 - 0.052 13.3 10.9 0.35 10.7 3.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain ANAPC4_WD40 PF12894.7 CEP16351.1 - 0.059 13.7 1.0 1.1 9.6 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DZR PF12773.7 CEP16351.1 - 0.42 10.7 14.5 0.9 9.6 14.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon IF4E PF01652.18 CEP16352.1 - 0.069 12.9 0.1 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E zf-C2H2 PF00096.26 CEP16352.1 - 0.15 12.6 1.5 0.25 11.9 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-CCHC PF00098.23 CEP16353.1 - 2.1e-05 24.4 2.8 3.2e-05 23.8 2.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CEP16353.1 - 0.0018 18.2 1.9 0.0053 16.7 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Exo_endo_phos_2 PF14529.6 CEP16356.1 - 0.0024 17.7 0.1 0.0086 15.9 0.0 2.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Fzo_mitofusin PF04799.13 CEP16356.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region RVT_1 PF00078.27 CEP16357.1 - 1.8e-29 102.8 0.0 2.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMEM215 PF15746.5 CEP16358.1 - 0.055 12.9 2.9 0.034 13.6 1.0 1.6 1 1 1 2 2 2 0 TMEM215 family ECM1 PF05782.11 CEP16358.1 - 0.62 8.9 4.5 0.73 8.7 4.5 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) FAM220 PF15487.6 CEP16358.1 - 3.8 7.1 7.4 5.9 6.4 7.4 1.4 1 1 0 1 1 1 0 FAM220 family Pneumo_att_G PF05539.11 CEP16358.1 - 6.1 6.3 12.7 6.9 6.2 12.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G OrfB_Zn_ribbon PF07282.11 CEP16359.1 - 1.9e-10 40.5 1.0 4.3e-10 39.4 1.0 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RuvX PF03652.15 CEP16359.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase FAR1 PF03101.15 CEP16361.1 - 1.1e-05 26.0 0.3 1.1e-05 26.0 0.3 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain F-box PF00646.33 CEP16362.1 - 0.00061 19.6 0.2 0.0023 17.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 CEP16362.1 - 0.0018 18.5 3.1 0.002 18.4 0.7 2.2 2 0 0 2 2 2 1 PRANC domain Homez PF11569.8 CEP16362.1 - 0.0021 17.5 0.6 0.084 12.4 0.8 2.4 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez PK_C PF02887.16 CEP16362.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain F-box_4 PF15966.5 CEP16362.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 CEP16362.1 - 0.035 14.0 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 F-box-like GBP_repeat PF02526.14 CEP16362.1 - 0.45 10.3 3.9 0.32 10.7 1.0 2.2 3 0 0 3 3 3 0 Glycophorin-binding protein Acetyltransf_3 PF13302.7 CEP16363.1 - 2.9e-16 60.4 0.0 3.2e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CEP16363.1 - 0.0068 16.1 0.1 0.49 10.1 0.1 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP16363.1 - 0.022 15.0 0.0 0.029 14.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_1 PF00076.22 CEP16364.1 - 3.9e-20 71.4 0.1 6.9e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP16364.1 - 0.00035 20.2 0.8 0.00098 18.7 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUP50 PF08911.11 CEP16364.1 - 0.24 12.1 4.6 0.64 10.7 4.6 1.6 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) RdRP PF05183.12 CEP16365.1 - 5.6e-107 358.8 0.0 4.2e-93 313.0 0.0 2.2 1 1 1 2 2 2 2 RNA dependent RNA polymerase DUF3795 PF12675.7 CEP16365.1 - 0.074 13.5 0.7 0.25 11.8 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) 2CSK_N PF08521.10 CEP16365.1 - 0.21 11.6 0.4 6.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal Nucleoporin_FG2 PF15967.5 CEP16365.1 - 0.65 8.5 4.7 1 7.8 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region KAR PF15222.6 CEP16365.1 - 1.5 9.2 6.7 0.89 9.9 2.6 2.7 3 0 0 3 3 3 0 Kidney androgen-regulated LIM PF00412.22 CEP16366.1 - 1.3e-24 86.1 58.6 2.9e-11 43.4 2.4 5.8 5 1 0 5 5 5 5 LIM domain Ribosomal_L6 PF00347.23 CEP16367.1 - 2.5e-33 114.6 7.8 3.9e-19 69.1 3.2 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.12 CEP16367.1 - 0.034 14.5 1.7 1.8 8.9 0.1 2.8 3 0 0 3 3 3 0 YbbR-like protein Pkinase PF00069.25 CEP16368.1 - 5.7e-53 180.0 0.0 8.7e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16368.1 - 8.3e-32 110.5 0.0 1.2e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP16368.1 - 1.9e-09 37.3 0.0 4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SWI-SNF_Ssr4 PF08549.10 CEP16368.1 - 0.031 13.0 5.5 0.039 12.6 5.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FTA2 PF13095.6 CEP16368.1 - 0.059 13.0 1.3 0.89 9.1 0.0 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP16368.1 - 0.069 13.1 0.0 8.1 6.3 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_binding_6 PF08030.12 CEP16368.1 - 0.15 12.2 3.7 0.55 10.4 0.1 2.6 3 0 0 3 3 3 0 Ferric reductase NAD binding domain ZZ PF00569.17 CEP16369.1 - 6.1e-09 35.6 3.4 1e-08 34.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CEP16369.1 - 1.8e-06 28.0 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP16369.1 - 0.0017 18.5 0.3 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Zn_ribbon_2 PF12674.7 CEP16369.1 - 0.04 14.6 0.9 0.13 12.9 0.9 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain C1_2 PF03107.16 CEP16369.1 - 0.058 13.7 2.3 0.13 12.6 2.3 1.5 1 0 0 1 1 1 0 C1 domain zf-UBR PF02207.20 CEP16369.1 - 0.32 11.2 6.1 1.1 9.5 6.0 1.9 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Adap_comp_sub PF00928.21 CEP16370.1 - 2.7e-67 226.9 0.0 3.3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEP16370.1 - 2.1e-08 34.2 0.3 7.7e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Pkinase PF00069.25 CEP16371.1 - 5.2e-16 58.8 0.0 1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16371.1 - 0.00094 18.5 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 CEP16371.1 - 0.01 15.8 5.5 0.061 13.3 0.0 3.6 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 RF3_C PF16658.5 CEP16371.1 - 0.042 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Insulin PF00049.18 CEP16371.1 - 0.055 14.5 0.4 0.2 12.7 0.2 2.0 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family SUIM_assoc PF16619.5 CEP16371.1 - 0.36 10.9 3.1 0.92 9.6 3.1 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SH3_9 PF14604.6 CEP16373.1 - 1.7e-10 40.6 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 CEP16373.1 - 5.5e-10 39.4 0.4 5.5e-10 39.4 0.4 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CEP16373.1 - 1.3e-08 34.3 0.1 2.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP16373.1 - 7.3e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PRKCSH PF07915.13 CEP16373.1 - 0.089 13.8 2.0 0.67 11.0 2.0 2.6 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein RskA PF10099.9 CEP16373.1 - 0.41 10.9 9.0 1.4 9.2 0.2 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DAO PF01266.24 CEP16374.1 - 1.3e-50 173.0 0.0 1.9e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CEP16374.1 - 1.6e-43 147.6 0.0 3.4e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CEP16374.1 - 5.5e-08 32.3 0.9 0.0037 16.4 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CEP16374.1 - 1.1e-05 24.9 2.5 0.0062 15.9 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CEP16374.1 - 2.1e-05 24.0 0.6 0.00019 20.8 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CEP16374.1 - 0.0086 15.3 0.7 0.049 12.9 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP16374.1 - 0.026 13.6 0.5 1.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CEP16374.1 - 0.03 14.6 0.3 0.17 12.2 0.4 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CEP16374.1 - 0.073 12.9 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CEP16374.1 - 0.082 12.1 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 CEP16375.1 - 4.9e-36 122.1 11.1 9.4e-08 32.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16375.1 - 4.2e-15 55.8 1.1 0.0014 18.9 0.1 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP16375.1 - 6.4e-06 26.2 0.5 0.12 12.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 CEP16375.1 - 0.024 14.2 0.0 0.068 12.8 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 CEP16375.1 - 0.028 13.1 0.2 0.073 11.7 0.0 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP16375.1 - 0.15 11.0 1.6 13 4.6 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Polysacc_deac_1 PF01522.21 CEP16376.1 - 3.1e-25 88.5 0.0 7e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP16376.1 - 0.01 15.0 0.0 0.025 13.8 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 tRNA_int_endo PF01974.17 CEP16377.1 - 2.2e-21 75.7 0.1 6e-21 74.3 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CEP16377.1 - 5.4e-06 26.0 0.0 5.8e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain GST_N_3 PF13417.6 CEP16378.1 - 4.1e-13 49.6 0.1 1.3e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP16378.1 - 8.9e-09 35.6 0.0 4.4e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP16378.1 - 5.7e-07 29.8 0.0 1.8e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Gly_transf_sug PF04488.15 CEP16378.1 - 2.9e-06 27.8 0.0 8.4e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CEP16378.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein CENP-K PF11802.8 CEP16379.1 - 5.9e-19 68.7 7.5 9.7e-19 68.0 7.1 1.6 1 1 0 1 1 1 1 Centromere-associated protein K tRNA_lig_CPD PF08302.11 CEP16379.1 - 0.15 11.5 7.9 0.03 13.8 3.7 1.8 1 1 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain DUF2383 PF09537.10 CEP16379.1 - 0.28 11.5 4.0 0.47 10.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) TAFII55_N PF04658.13 CEP16380.1 - 4.2e-51 172.9 0.3 4.2e-51 172.9 0.3 2.2 2 1 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 CEP16380.1 - 4.1e-07 29.7 15.5 4.1e-07 29.7 15.5 2.4 2 1 0 3 3 3 1 BUD22 SURF2 PF05477.11 CEP16380.1 - 0.0082 15.9 13.4 0.0082 15.9 13.4 1.7 2 0 0 2 2 2 1 Surfeit locus protein 2 (SURF2) DUF2428 PF10350.9 CEP16380.1 - 0.067 12.4 1.3 0.14 11.4 1.3 1.7 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Arc_PepC_II PF06847.11 CEP16380.1 - 0.099 13.2 0.3 0.099 13.2 0.3 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DUF5312 PF17239.2 CEP16380.1 - 0.48 8.7 6.8 0.037 12.4 2.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5312) RRN3 PF05327.11 CEP16380.1 - 2.6 6.5 22.5 5.6 5.4 22.5 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 CEP16380.1 - 8 4.5 34.9 0.2 9.8 28.8 1.4 2 0 0 2 2 2 0 Nop14-like family Fungal_trans PF04082.18 CEP16381.1 - 7.1e-44 149.8 0.2 7.1e-44 149.8 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP16381.1 - 1.2e-09 38.1 13.1 2.3e-09 37.2 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suf PF05843.14 CEP16381.1 - 1.6 8.6 7.0 1.1 9.2 1.8 2.5 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 CEP16381.1 - 3.5 7.2 21.3 3.6 7.1 11.8 2.8 3 0 0 3 3 3 0 Spt20 family RAI16-like PF10257.9 CEP16382.1 - 4.7e-74 249.4 1.8 7.4e-74 248.8 1.8 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein adh_short_C2 PF13561.6 CEP16383.1 - 3.2e-70 236.3 1.1 3.7e-70 236.1 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP16383.1 - 2.3e-53 180.6 2.0 2.8e-53 180.3 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP16383.1 - 9e-10 38.7 1.4 1.3e-09 38.2 1.4 1.2 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 CEP16383.1 - 0.00052 19.6 0.3 0.00082 19.0 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 CEP16383.1 - 0.0011 18.9 1.0 0.0019 18.1 1.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain D123 PF07065.14 CEP16384.1 - 2.6e-112 374.9 6.6 3.1e-112 374.7 6.6 1.1 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 CEP16384.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 H2O2_YaaD PF03883.14 CEP16384.1 - 0.027 14.0 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Peroxide stress protein YaaA Ras PF00071.22 CEP16385.1 - 8.7e-58 194.5 0.1 1e-57 194.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP16385.1 - 2.1e-32 111.9 0.0 3.2e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP16385.1 - 8e-13 48.2 0.0 9.9e-13 47.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP16385.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP16385.1 - 1.8e-05 24.2 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEP16385.1 - 5.5e-05 23.1 0.3 0.0039 17.1 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 CEP16385.1 - 0.0012 18.6 0.2 0.11 12.2 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CEP16385.1 - 0.0027 17.3 0.0 0.0073 15.9 0.0 1.6 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CEP16385.1 - 0.0032 17.8 0.0 0.0055 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP16385.1 - 0.0032 17.9 0.0 0.005 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 CEP16385.1 - 0.006 15.9 0.6 0.02 14.2 0.1 2.0 3 0 0 3 3 3 1 Septin AAA_5 PF07728.14 CEP16385.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CEP16385.1 - 0.013 15.0 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CEP16385.1 - 0.015 15.1 0.3 0.52 10.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CEP16385.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NTPase SRPRB PF09439.10 CEP16385.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CEP16385.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CEP16385.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 CEP16385.1 - 0.062 13.2 0.6 0.099 12.5 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 CEP16385.1 - 0.071 12.3 0.5 0.47 9.6 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 CEP16385.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 CEP16385.1 - 0.079 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF5102 PF17104.5 CEP16386.1 - 1.6e-29 103.9 9.3 1.6e-29 103.9 9.3 2.4 1 1 2 3 3 3 2 Domain of unknown function (DUF5102) DELLA PF12041.8 CEP16386.1 - 0.046 13.6 0.2 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal GPI-anchored PF10342.9 CEP16387.1 - 0.00099 19.8 1.0 0.00099 19.8 1.0 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4203 PF13886.6 CEP16388.1 - 1.7e-20 73.6 21.2 1.7e-20 73.6 21.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) PWWP PF00855.17 CEP16389.1 - 2.6e-18 66.2 1.3 5.4e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CEP16389.1 - 4.4e-07 29.8 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CDC45 PF02724.14 CEP16389.1 - 0.23 9.7 12.0 0.32 9.2 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein E7 PF00527.18 CEP16389.1 - 1.2 9.4 3.8 5.4 7.3 0.7 2.5 2 0 0 2 2 2 0 E7 protein, Early protein FAM176 PF14851.6 CEP16389.1 - 2 8.1 7.5 13 5.5 3.0 2.4 2 0 0 2 2 2 0 FAM176 family PQ-loop PF04193.14 CEP16390.1 - 3.5e-22 77.9 9.8 5.7e-13 48.4 1.4 3.5 3 1 0 3 3 3 2 PQ loop repeat 4HBT PF03061.22 CEP16391.1 - 4.3e-09 36.6 0.0 7.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RNase_PH PF01138.21 CEP16392.1 - 2e-24 86.6 0.0 3.3e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP16392.1 - 2.2e-10 40.4 0.1 5.6e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Glyco_trans_2_3 PF13632.6 CEP16393.1 - 2.3e-17 63.6 0.8 3.7e-17 62.9 0.8 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 RCC1 PF00415.18 CEP16394.1 - 2.7e-17 63.1 10.4 1.3e-05 25.7 0.2 6.9 6 2 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEP16394.1 - 9.1e-14 50.8 19.7 2.6e-05 23.9 0.7 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 CEP16394.1 - 2.8e-07 30.3 0.3 5.5e-07 29.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CEP16394.1 - 0.00026 20.9 0.0 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 CEP16394.1 - 0.00039 20.2 0.4 0.0008 19.2 0.4 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 CEP16394.1 - 0.021 15.4 0.2 0.045 14.3 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Spectrin_like PF18373.1 CEP16395.1 - 0.0053 16.8 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 Spectrin like domain MADF_DNA_bdg PF10545.9 CEP16395.1 - 0.065 13.6 0.1 0.82 10.0 0.0 2.4 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FYVE PF01363.21 CEP16396.1 - 2.2e-20 72.6 4.8 5.3e-20 71.3 4.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 CEP16396.1 - 2.2e-05 24.3 1.2 12 6.2 0.0 5.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat IBR PF01485.21 CEP16396.1 - 0.0037 17.4 4.0 0.01 16.1 4.0 1.7 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TetR_C_26 PF17934.1 CEP16396.1 - 0.044 14.1 0.2 0.15 12.4 0.2 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain C1_1 PF00130.22 CEP16396.1 - 0.09 12.7 4.5 0.21 11.5 4.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 CEP16396.1 - 0.11 12.7 2.8 0.37 11.0 2.8 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger CN_hydrolase PF00795.22 CEP16397.1 - 1.8e-63 214.3 0.0 2.1e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TruB_C PF09142.11 CEP16397.1 - 0.095 12.5 0.3 2.7 7.9 0.0 2.8 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal EF-hand_1 PF00036.32 CEP16398.1 - 8.7e-15 53.1 4.4 0.00012 21.4 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CEP16398.1 - 3.6e-13 48.3 3.0 2.3e-05 24.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CEP16398.1 - 2.3e-11 43.4 2.9 0.0078 16.0 0.1 4.0 2 1 1 3 3 3 3 EF-hand domain pair ZZ PF00569.17 CEP16398.1 - 5.7e-11 42.0 5.7 9.4e-11 41.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 CEP16398.1 - 1.5e-09 38.2 11.1 0.00027 21.3 0.5 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CEP16398.1 - 2e-08 33.4 3.0 0.00066 19.1 0.0 3.7 3 0 0 3 3 3 2 EF hand TackOD1 PF18551.1 CEP16398.1 - 0.0038 16.9 0.7 0.011 15.4 0.7 1.8 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 C1_2 PF03107.16 CEP16398.1 - 0.018 15.3 3.3 0.034 14.5 3.3 1.4 1 0 0 1 1 1 0 C1 domain Caleosin PF05042.13 CEP16398.1 - 0.13 12.2 3.0 4.4 7.2 0.1 3.3 2 1 1 3 3 3 0 Caleosin related protein EF-hand_14 PF17959.1 CEP16398.1 - 0.14 12.5 0.2 12 6.3 0.1 3.1 2 1 0 2 2 2 0 EF-hand domain DUF4611 PF15387.6 CEP16398.1 - 9 6.6 9.8 1.2 9.4 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3752 PF12572.8 CEP16399.1 - 8.9e-28 97.7 9.7 8.9e-28 97.7 9.7 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3752) RteC PF09357.10 CEP16399.1 - 0.028 14.1 0.3 0.058 13.1 0.3 1.4 1 0 0 1 1 1 0 RteC protein DUF5602 PF18197.1 CEP16399.1 - 0.057 13.9 0.2 6.2 7.4 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5602) RVT_1 PF00078.27 CEP16402.1 - 5.5e-12 45.7 0.2 1.1e-11 44.7 0.2 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3388 PF11868.8 CEP16402.1 - 0.0062 15.9 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) gag-asp_proteas PF13975.6 CEP16403.1 - 0.049 14.2 0.0 0.17 12.5 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP16403.1 - 0.079 13.6 0.1 0.84 10.3 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease RT_RNaseH_2 PF17919.1 CEP16404.1 - 2.4e-07 30.7 0.2 1.1e-05 25.4 0.0 2.4 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16404.1 - 6e-07 29.7 0.1 0.011 16.0 0.1 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Pepsin-I3 PF06394.13 CEP16404.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Chromo PF00385.24 CEP16405.1 - 2.6e-08 33.6 2.2 6.5e-08 32.4 2.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP16405.1 - 0.023 14.6 4.9 0.035 14.0 0.2 2.8 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain DUF4252 PF14060.6 CEP16406.1 - 0.0032 17.4 1.1 0.01 15.7 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4252) DUF1577 PF07614.11 CEP16406.1 - 0.037 13.1 1.8 0.071 12.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) TOH_N PF12549.8 CEP16406.1 - 0.95 9.4 2.1 40 4.2 0.0 3.3 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal HEAT PF02985.22 CEP16409.1 - 0.025 14.8 0.0 25 5.5 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CEP16409.1 - 0.038 14.6 0.0 0.18 12.4 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Asp PF00026.23 CEP16410.1 - 2.9e-58 197.7 0.6 4.5e-58 197.1 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP16410.1 - 4.4e-16 59.6 1.3 1.1e-13 51.8 1.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MULE PF10551.9 CEP16411.1 - 0.00025 21.4 0.2 0.001 19.5 0.2 2.2 1 0 0 1 1 1 1 MULE transposase domain LIAS_N PF16881.5 CEP16411.1 - 0.031 14.7 0.1 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Cupin_8 PF13621.6 CEP16411.1 - 0.23 11.2 2.3 1.9 8.1 0.4 2.5 2 0 0 2 2 2 0 Cupin-like domain SesA PF17107.5 CEP16412.1 - 0.067 13.4 0.0 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NCBP3 PF10309.9 CEP16412.1 - 0.13 12.2 0.3 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Nuclear cap-binding protein subunit 3 DDE_3 PF13358.6 CEP16413.1 - 6.8e-27 94.0 0.0 1.5e-17 63.8 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP16413.1 - 1.9e-07 30.7 0.1 8.8e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP16413.1 - 4.6e-05 23.9 0.0 0.0064 17.1 0.0 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.6 CEP16413.1 - 0.0026 17.8 0.1 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Stork_head PF10264.9 CEP16413.1 - 0.0096 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain HTH_Tnp_1 PF01527.20 CEP16413.1 - 0.017 15.4 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Transposase HTH_Tnp_ISL3 PF13542.6 CEP16413.1 - 0.042 13.3 0.1 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF1804 PF08822.11 CEP16413.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Bromodomain PF00439.25 CEP16414.1 - 4e-39 132.6 1.2 6.7e-21 74.2 0.1 2.6 2 0 0 2 2 2 2 Bromodomain ArfGap PF01412.18 CEP16416.1 - 4.2e-35 120.4 0.1 4.2e-35 120.4 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CEP16416.1 - 2.8e-16 60.0 8.4 5.1e-16 59.1 8.4 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CEP16416.1 - 7.3e-13 48.9 0.1 7.3e-13 48.9 0.1 2.5 3 0 0 3 3 3 1 PH domain KapB PF08810.10 CEP16416.1 - 6.2 7.0 7.3 4.1 7.6 1.5 2.9 3 0 0 3 3 3 0 Kinase associated protein B CENP-F_leu_zip PF10473.9 CEP16417.1 - 0.0037 17.3 4.9 0.0037 17.3 4.9 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rxt3 PF08642.10 CEP16417.1 - 0.22 12.3 5.0 0.18 12.6 2.3 2.2 2 1 1 3 3 3 0 Histone deacetylation protein Rxt3 Spc24 PF08286.11 CEP16417.1 - 1.1 9.6 7.3 0.95 9.7 2.3 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Sigma70_ner PF04546.13 CEP16417.1 - 3.8 7.3 15.1 3.7 7.4 4.7 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Pkinase PF00069.25 CEP16418.1 - 1.4e-41 142.6 1.0 1.1e-20 74.1 0.1 3.7 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16418.1 - 8.5e-11 41.6 0.0 4.6e-08 32.7 0.0 3.3 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 CEP16418.1 - 0.00064 19.7 0.0 0.034 14.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family TPR_2 PF07719.17 CEP16418.1 - 0.049 13.8 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP16418.1 - 0.054 13.3 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Kdo PF06293.14 CEP16418.1 - 0.1 11.9 0.2 0.34 10.2 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 CEP16418.1 - 0.13 13.2 0.1 0.68 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ESP PF16590.5 CEP16418.1 - 2.2 8.6 8.1 0.38 11.1 2.2 2.7 3 0 0 3 3 3 0 Exocrine gland-secreting peptide O-FucT PF10250.9 CEP16420.1 - 1.1e-05 25.3 0.2 5e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase COX16 PF14138.6 CEP16421.1 - 1.7e-29 102.1 0.0 2.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Glutaredoxin PF00462.24 CEP16422.1 - 1e-09 38.4 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin RNA_pol_Rpb2_3 PF04565.16 CEP16422.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 RasGAP PF00616.19 CEP16423.1 - 4.7e-49 166.9 1.5 1.2e-48 165.6 1.5 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEP16423.1 - 4.6e-36 124.0 4.8 1.3e-35 122.5 0.2 3.5 4 0 0 4 4 4 1 RasGAP C-terminus CH PF00307.31 CEP16423.1 - 3.9e-14 52.7 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 CEP16423.1 - 0.14 12.0 1.9 0.3 11.0 0.1 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif CBFD_NFYB_HMF PF00808.23 CEP16424.1 - 1.1e-18 67.2 0.7 1.8e-18 66.6 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CEP16424.1 - 0.017 15.5 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 CEP16424.1 - 0.059 13.6 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 CENP-W protein Suc_Fer-like PF06999.12 CEP16425.1 - 2.6e-25 89.4 2.1 5.8e-22 78.5 1.7 2.0 2 0 0 2 2 2 2 Sucrase/ferredoxin-like Sec2p PF06428.11 CEP16426.1 - 8.2e-23 80.2 13.2 8.2e-23 80.2 13.2 3.0 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p HOCHOB PF17943.1 CEP16426.1 - 0.096 13.4 1.4 0.15 12.8 0.2 1.9 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox Flagellin_C PF00700.21 CEP16426.1 - 0.099 13.0 4.4 3.8 8.0 0.7 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF1826 PF08856.11 CEP16426.1 - 0.45 10.4 5.8 0.25 11.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) V_ATPase_I PF01496.19 CEP16426.1 - 0.53 8.1 16.4 0.16 9.9 13.2 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 CEP16426.1 - 2.2 9.0 15.5 3.7 8.3 3.4 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 CEP16426.1 - 2.2 7.5 16.2 0.48 9.6 5.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein Nas2_N PF18265.1 CEP16426.1 - 2.8 7.9 16.2 4.4 7.3 5.3 4.4 3 1 0 3 3 3 0 Nas2 N_terminal domain DUF948 PF06103.11 CEP16426.1 - 2.9 8.2 5.1 1.7 8.9 0.7 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.8 CEP16426.1 - 3.7 6.7 19.3 0.49 9.6 6.6 2.5 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 MAD PF05557.13 CEP16426.1 - 5.4 5.3 31.8 0.39 9.0 9.9 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein LRR_6 PF13516.6 CEP16427.1 - 2.4e-11 42.7 16.2 0.011 15.7 0.1 9.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 CEP16427.1 - 0.0011 19.4 24.6 6.2 7.4 0.1 8.4 6 3 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP16427.1 - 0.54 11.0 11.2 94 4.2 0.0 6.9 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 CEP16427.1 - 8.4 6.2 20.2 11 5.8 1.2 6.7 4 3 2 7 7 7 0 Leucine rich repeat MFS_MOT1 PF16983.5 CEP16428.1 - 1.6e-57 192.7 30.6 7.3e-34 116.5 9.2 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily BenE PF03594.13 CEP16428.1 - 0.0094 14.8 2.5 0.0094 14.8 2.5 2.6 4 0 0 4 4 4 2 Benzoate membrane transport protein DUF3446 PF11928.8 CEP16428.1 - 1.4 9.2 12.4 1.7 9.0 8.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain COG6 PF06419.11 CEP16429.1 - 3.5e-179 597.0 5.3 3.9e-179 596.9 5.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 APC_N_CC PF16689.5 CEP16429.1 - 0.042 13.9 0.0 0.18 11.9 0.0 2.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain PspA_IM30 PF04012.12 CEP16429.1 - 0.062 12.9 4.5 0.56 9.8 1.6 3.2 2 1 1 3 3 3 0 PspA/IM30 family DnaG_DnaB_bind PF08278.11 CEP16429.1 - 0.12 13.0 2.3 0.66 10.6 0.0 3.0 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding GLTP PF08718.11 CEP16429.1 - 0.53 10.5 2.9 3.2 8.0 1.1 3.1 3 1 0 3 3 3 0 Glycolipid transfer protein (GLTP) Peptidase_C50 PF03568.17 CEP16430.1 - 2.6e-111 372.5 0.0 1.1e-110 370.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 CEP16430.1 - 1.8e-05 24.9 5.5 4.4 7.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP16430.1 - 0.00012 21.9 12.5 0.13 12.4 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat CHAT PF12770.7 CEP16430.1 - 0.00051 19.5 0.0 0.00051 19.5 0.0 2.4 3 0 0 3 3 3 1 CHAT domain RNase_H2-Ydr279 PF09468.10 CEP16430.1 - 0.016 15.4 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain TPR_1 PF00515.28 CEP16430.1 - 0.019 14.8 8.1 0.36 10.7 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 CEP16430.1 - 0.19 11.4 2.7 2.3 7.9 0.4 3.4 2 1 1 3 3 3 0 26S proteasome subunit RPN7 PB1 PF00564.24 CEP16431.1 - 2.3e-10 40.3 0.1 5.4e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 PB1 domain Pkinase PF00069.25 CEP16432.1 - 5.7e-67 225.9 0.0 8.5e-66 222.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16432.1 - 1.1e-27 97.0 0.0 9.8e-23 80.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP16432.1 - 4.2e-09 36.1 0.4 0.00084 18.7 0.1 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 CEP16432.1 - 0.00067 19.3 0.6 0.0017 18.0 0.6 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CEP16432.1 - 0.006 15.4 0.0 0.033 13.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Xpo1 PF08389.12 CEP16433.1 - 1.7e-40 138.5 1.3 3.9e-36 124.3 0.1 3.8 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 CEP16433.1 - 5.6e-07 29.4 1.0 5.1e-06 26.3 0.1 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF5388 PF17363.2 CEP16433.1 - 0.018 15.3 0.0 0.1 12.8 0.0 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5388) CsgA PF17334.2 CEP16433.1 - 0.052 14.3 0.6 20 6.0 0.0 4.0 4 0 0 4 4 4 0 Minor curli fiber component A Sec1 PF00995.23 CEP16434.1 - 1.9e-107 360.9 0.4 2.5e-107 360.5 0.4 1.1 1 0 0 1 1 1 1 Sec1 family Transket_pyr PF02779.24 CEP16434.1 - 2.1e-45 154.6 0.0 4.1e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CEP16434.1 - 1.2e-39 135.0 0.0 3.3e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Ammonium_transp PF00909.21 CEP16435.1 - 1.6e-96 323.4 33.7 2.5e-61 207.6 9.4 3.0 3 0 0 3 3 3 3 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CEP16435.1 - 0.85 9.7 7.6 0.053 13.5 1.1 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S PrmA PF06325.13 CEP16436.1 - 4.4e-06 26.3 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEP16436.1 - 8.8e-06 26.3 0.0 3.6e-05 24.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP16436.1 - 5.4e-05 23.8 0.0 0.00033 21.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CEP16436.1 - 0.0017 17.9 0.0 0.0071 15.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CEP16436.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEP16436.1 - 0.0038 16.9 0.2 0.42 10.2 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PRMT5_C PF17286.2 CEP16436.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain GidB PF02527.15 CEP16436.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G UBM PF14377.6 CEP16439.1 - 0.33 10.5 0.8 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin binding region DUF4451 PF14616.6 CEP16441.1 - 9.1e-16 58.2 7.4 2.6e-15 56.7 7.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zinc_ribbon_9 PF14369.6 CEP16441.1 - 0.19 12.0 1.3 0.63 10.3 1.3 1.8 1 0 0 1 1 1 0 zinc-ribbon WD40 PF00400.32 CEP16442.1 - 6.6e-40 134.4 24.0 1.7e-06 28.7 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16442.1 - 4.5e-09 36.5 1.9 3.1 8.2 0.0 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP16442.1 - 1.5e-08 34.3 0.7 2.2e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CEP16442.1 - 2.2e-07 29.9 7.3 0.46 9.1 0.0 5.7 2 2 1 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CEP16442.1 - 8e-05 22.6 0.4 2.3 8.3 0.0 4.8 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Arylsulfotran_2 PF14269.6 CEP16442.1 - 0.012 15.0 0.6 0.044 13.1 0.0 2.2 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) PQQ_3 PF13570.6 CEP16442.1 - 0.038 14.5 0.3 12 6.5 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain PQQ_2 PF13360.6 CEP16442.1 - 0.046 13.3 0.2 0.53 9.8 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain zf-H2C2_2 PF13465.6 CEP16444.1 - 2.4e-08 34.0 11.4 0.00011 22.4 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP16444.1 - 2.2e-06 27.8 14.4 0.0016 18.8 3.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP16444.1 - 1.8e-05 25.1 12.1 0.01 16.6 2.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP16444.1 - 0.003 17.8 6.5 0.73 10.2 5.3 3.2 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 CEP16444.1 - 0.015 15.7 2.9 0.016 15.6 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CEP16444.1 - 0.03 14.3 4.1 0.048 13.7 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP16444.1 - 0.59 10.5 2.8 0.74 10.2 0.3 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Clat_adaptor_s PF01217.20 CEP16445.1 - 2e-27 95.9 1.4 2.5e-27 95.5 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1235 PF06822.12 CEP16445.1 - 0.041 13.2 0.2 0.071 12.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1235) Ubiquitin_4 PF18036.1 CEP16446.1 - 6.7e-23 80.5 1.0 1.2e-22 79.7 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Par3_HAL_N_term PF12053.8 CEP16446.1 - 0.0019 18.4 0.3 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal of Par3 and HAL proteins Phage_sheath_1N PF17481.2 CEP16446.1 - 0.01 16.3 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Phage tail sheath protein beta-sandwich domain RNA_pol_Rpb5_C PF01191.19 CEP16446.1 - 0.034 14.0 0.7 0.11 12.4 0.0 2.2 3 1 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain ubiquitin PF00240.23 CEP16446.1 - 0.06 13.1 0.8 4 7.3 0.0 2.9 2 1 1 3 3 3 0 Ubiquitin family WD40 PF00400.32 CEP16447.1 - 1.8e-26 91.8 14.5 6.3e-07 30.0 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16447.1 - 3.6e-06 27.2 0.3 1.9 8.8 0.0 4.2 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP16447.1 - 0.0033 16.5 0.0 0.03 13.3 0.0 2.6 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP16447.1 - 0.0043 15.8 0.5 0.051 12.2 0.1 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 GluRS_N PF18466.1 CEP16447.1 - 0.13 12.6 1.3 0.35 11.3 1.3 1.7 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain PEPCK_ATP PF01293.20 CEP16449.1 - 1.4e-224 746.0 0.0 1.7e-224 745.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 CEP16449.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Gti1_Pac2 PF09729.9 CEP16450.1 - 1.5e-43 149.0 4.7 9.9e-38 130.0 0.8 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Nairo_nucleo PF02477.15 CEP16450.1 - 0.21 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein PP2C PF00481.21 CEP16451.1 - 4e-80 269.2 0.0 5.1e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Isochorismatase PF00857.20 CEP16452.1 - 2e-24 86.7 0.3 4.2e-24 85.7 0.3 1.5 1 1 0 1 1 1 1 Isochorismatase family Glyco_trans_4_2 PF13477.6 CEP16452.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like zf-ZPR1 PF03367.13 CEP16452.1 - 0.047 13.5 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain DUF4566 PF15130.6 CEP16452.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4566) DUF2315 PF10231.9 CEP16453.1 - 4e-29 101.2 5.0 1.2e-21 77.1 0.4 2.3 1 1 1 2 2 2 2 Apoptogenic protein 1 WD40 PF00400.32 CEP16454.1 - 6.6e-37 124.9 22.1 2.1e-07 31.5 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16454.1 - 1.1e-08 35.2 0.1 0.082 13.2 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP16454.1 - 2.8e-08 32.9 8.1 0.013 14.2 0.2 4.6 3 2 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CEP16454.1 - 0.019 14.3 0.0 0.089 12.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 CEP16454.1 - 0.029 13.3 0.1 11 4.8 0.1 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UPF0449 PF15136.6 CEP16454.1 - 0.042 14.3 0.5 0.11 13.0 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Sec34 PF04136.15 CEP16454.1 - 0.23 11.4 2.9 0.53 10.2 2.9 1.6 1 0 0 1 1 1 0 Sec34-like family Spc24 PF08286.11 CEP16454.1 - 1.5 9.1 6.7 0.22 11.8 2.2 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 CEP16454.1 - 2.1 9.0 4.8 0.4 11.3 0.8 1.9 2 0 0 2 2 2 0 Initiation control protein YabA LRR_4 PF12799.7 CEP16455.1 - 2e-10 40.8 15.2 0.022 15.2 0.0 7.7 3 2 6 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP16455.1 - 2.2e-09 36.6 16.0 1.6 9.0 0.0 10.5 12 0 0 12 12 12 3 Leucine Rich repeat F-box-like PF12937.7 CEP16455.1 - 4.7e-09 36.0 0.2 4.7e-09 36.0 0.2 3.3 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 CEP16455.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 3.8 5 0 0 5 5 5 1 F-box domain F-box_5 PF18511.1 CEP16455.1 - 0.0049 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box Snapin_Pallidin PF14712.6 CEP16457.1 - 7e-06 26.4 1.3 7e-06 26.4 1.3 2.0 2 0 0 2 2 2 1 Snapin/Pallidin RVT_1 PF00078.27 CEP16457.1 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF-5_eIF-2B PF01873.17 CEP16458.1 - 1.2e-40 138.0 0.1 2.3e-40 137.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CEP16458.1 - 0.0027 17.2 0.2 0.0057 16.1 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 CEP16458.1 - 0.0095 15.7 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Lar_restr_allev PF14354.6 CEP16458.1 - 0.095 13.1 1.0 0.53 10.7 1.0 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-HYPF PF07503.12 CEP16458.1 - 0.12 12.1 0.2 19 5.2 0.0 2.4 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 CEP16458.1 - 4.2 7.8 6.8 8.2 6.8 0.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain FAR1 PF03101.15 CEP16459.1 - 0.0016 19.1 0.5 0.0016 19.1 0.5 1.9 1 1 1 2 2 2 1 FAR1 DNA-binding domain TFIIA PF03153.13 CEP16459.1 - 0.005 16.9 16.6 0.0054 16.8 16.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pullulanase_Ins PF18494.1 CEP16459.1 - 0.52 10.8 3.5 6.5 7.3 0.7 2.6 2 1 0 2 2 2 0 Pullulanase Ins domain PepSY_TM_like_2 PF16357.5 CEP16459.1 - 0.65 9.9 6.9 1.1 9.2 6.9 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like PepSY_TM PF03929.16 CEP16459.1 - 0.79 9.3 2.6 1 9.0 2.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Presenilin PF01080.17 CEP16459.1 - 3 6.5 4.5 3.7 6.2 4.5 1.2 1 0 0 1 1 1 0 Presenilin AAA PF00004.29 CEP16460.1 - 2.6e-59 199.4 0.0 7.7e-42 142.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CEP16460.1 - 1.8e-29 102.0 0.4 4.3e-29 100.8 0.4 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CEP16460.1 - 7.8e-13 48.0 0.2 6.3e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CEP16460.1 - 2.4e-12 47.6 4.7 5.2e-05 23.7 0.6 4.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 CEP16460.1 - 2.3e-06 27.7 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEP16460.1 - 3.4e-06 27.6 0.1 0.12 12.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CEP16460.1 - 5e-05 22.9 0.0 0.012 15.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 CEP16460.1 - 7.6e-05 22.0 0.0 0.0062 15.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CEP16460.1 - 9.1e-05 22.6 0.0 0.04 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP16460.1 - 9.8e-05 22.6 2.6 0.87 9.9 0.1 4.0 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 CEP16460.1 - 0.00012 22.1 0.1 0.24 11.4 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CEP16460.1 - 0.00012 21.9 0.0 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CEP16460.1 - 0.00018 21.9 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 CEP16460.1 - 0.00041 20.4 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CEP16460.1 - 0.00042 20.1 0.0 0.56 9.9 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CEP16460.1 - 0.00096 18.3 0.1 0.0067 15.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein TIP49 PF06068.13 CEP16460.1 - 0.00098 18.4 0.0 0.1 11.8 0.0 2.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 CEP16460.1 - 0.0016 18.2 0.1 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CEP16460.1 - 0.0017 18.1 0.0 0.37 10.5 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CEP16460.1 - 0.0026 18.2 0.0 0.34 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CEP16460.1 - 0.0049 16.3 0.1 0.73 9.2 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CEP16460.1 - 0.005 16.8 0.0 0.62 9.9 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CEP16460.1 - 0.0054 16.7 3.1 3.9 7.4 0.5 3.6 3 1 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 CEP16460.1 - 0.0056 16.0 0.0 2.8 7.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.15 CEP16460.1 - 0.0083 16.1 0.1 0.45 10.4 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_29 PF13555.6 CEP16460.1 - 0.0094 15.7 0.0 0.27 11.0 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_2 PF07724.14 CEP16460.1 - 0.011 15.8 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 CEP16460.1 - 0.025 14.5 0.2 0.78 9.6 0.1 2.4 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 CEP16460.1 - 0.026 13.7 0.2 3.6 6.7 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_28 PF13521.6 CEP16460.1 - 0.029 14.6 0.0 8.3 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEP16460.1 - 0.031 14.8 0.0 12 6.4 0.0 3.0 2 0 0 2 2 2 0 ABC transporter RNA12 PF10443.9 CEP16460.1 - 0.034 12.9 0.0 0.073 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA12 protein cobW PF02492.19 CEP16460.1 - 0.045 13.4 0.8 0.86 9.2 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_3 PF07726.11 CEP16460.1 - 0.057 13.3 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_35 PF14516.6 CEP16460.1 - 0.065 12.1 0.0 0.2 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.6 CEP16460.1 - 0.065 13.6 0.0 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CEP16460.1 - 0.11 12.1 2.8 1.2 8.6 0.1 3.3 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CEP16460.1 - 0.13 11.4 0.1 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Peptidase_S9 PF00326.21 CEP16461.1 - 6.1e-55 186.0 0.5 6.1e-55 186.0 0.5 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family SRF-TF PF00319.18 CEP16461.1 - 1.2e-09 37.5 0.0 2.4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AXE1 PF05448.12 CEP16461.1 - 3.3e-06 26.0 0.0 0.00019 20.2 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PAT1 PF09770.9 CEP16461.1 - 0.014 13.7 32.9 0.025 12.9 32.9 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Homeodomain PF00046.29 CEP16462.1 - 2.5e-18 65.6 1.8 4.8e-18 64.8 1.8 1.5 1 0 0 1 1 1 1 Homeodomain DUF4611 PF15387.6 CEP16464.1 - 0.094 12.9 3.6 0.22 11.8 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Hrs_helical PF12210.8 CEP16464.1 - 0.17 12.4 2.6 13 6.4 0.0 2.5 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4724 PF15852.5 CEP16464.1 - 0.38 11.3 4.0 0.23 12.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) PolyA_pol PF01743.20 CEP16465.1 - 0.048 14.1 0.1 0.069 13.6 0.1 1.4 1 0 0 1 1 1 0 Poly A polymerase head domain RhoGAP PF00620.27 CEP16466.1 - 1.6e-37 128.7 0.0 4.1e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CEP16466.1 - 4.2e-07 30.1 13.7 1.5e-06 28.3 1.2 3.1 3 0 0 3 3 3 2 LIM domain DUF1708 PF08101.11 CEP16466.1 - 0.0096 15.1 0.0 0.0096 15.1 0.0 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1708) zf-ACC PF17848.1 CEP16466.1 - 1.7 8.8 4.4 12 6.1 0.1 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain GCIP PF13324.6 CEP16467.1 - 1.6e-37 129.6 2.1 1.9e-37 129.3 2.1 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Transferase PF02458.15 CEP16467.1 - 0.02 13.6 0.7 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 Transferase family NOA36 PF06524.12 CEP16467.1 - 0.15 11.4 0.1 0.15 11.4 0.1 2.3 1 1 1 2 2 2 0 NOA36 protein NDC10_II PF16787.5 CEP16469.1 - 2.3e-10 40.0 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Transket_pyr PF02779.24 CEP16470.1 - 6.8e-58 195.3 0.0 1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEP16470.1 - 1.1e-47 161.6 0.0 1.8e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 CEP16470.1 - 1.8e-45 155.2 0.0 4e-45 154.1 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component DnaJ-X PF14308.6 CEP16471.1 - 1.4e-50 171.7 8.9 1.4e-50 171.7 8.9 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CEP16471.1 - 3.8e-25 87.8 3.2 5.9e-25 87.2 1.7 2.2 2 0 0 2 2 2 1 DnaJ domain APG6 PF04111.12 CEP16471.1 - 0.075 13.0 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Apg6 BARA domain BofC_C PF08955.10 CEP16471.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 BofC C-terminal domain Mistic PF11458.8 CEP16471.1 - 0.23 11.5 4.1 0.2 11.6 0.5 2.8 3 1 0 3 3 3 0 Membrane-integrating protein Mistic WD40 PF00400.32 CEP16472.1 - 5.2e-21 74.6 11.2 0.00025 21.8 0.3 6.2 6 0 0 6 6 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16472.1 - 3.6e-06 27.2 1.5 0.45 10.8 0.1 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pex14_N PF04695.13 CEP16472.1 - 0.19 12.4 30.4 1.9 9.1 10.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region US2 PF02476.15 CEP16472.1 - 0.62 10.8 5.5 0.23 12.2 1.4 2.2 2 0 0 2 2 2 0 US2 family DUF2722 PF10846.8 CEP16472.1 - 0.76 8.7 33.7 0.059 12.3 11.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ECH_1 PF00378.20 CEP16472.1 - 0.8 9.0 5.1 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF775 PF05603.12 CEP16472.1 - 0.9 9.0 16.5 0.4 10.2 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Peptidase_U57 PF05582.12 CEP16472.1 - 1 8.5 4.9 4 6.6 0.2 2.2 2 0 0 2 2 2 0 YabG peptidase U57 Gti1_Pac2 PF09729.9 CEP16472.1 - 2.2 8.4 10.7 5.1 7.2 0.7 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family EPL1 PF10513.9 CEP16472.1 - 2.8 8.3 16.3 3.8 7.9 5.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Hydin_ADK PF17213.3 CEP16472.1 - 4.1 7.6 14.4 0.56 10.5 1.7 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Suf PF05843.14 CEP16472.1 - 4.3 7.2 22.3 3.6 7.5 5.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1387 PF07139.11 CEP16472.1 - 4.6 6.9 14.7 6.8 6.3 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Sporozoite_P67 PF05642.11 CEP16472.1 - 6.8 4.6 11.9 7.9 4.4 11.4 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF702 PF05142.12 CEP16472.1 - 9.2 6.7 14.0 3.3 8.2 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) AT_hook PF02178.19 CEP16473.1 - 3.7e-08 32.3 16.7 0.0074 16.0 2.7 3.9 3 0 0 3 3 3 3 AT hook motif Spore_coat_CotO PF14153.6 CEP16473.1 - 1.1 9.1 14.8 1.4 8.8 14.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CCSAP PF15748.5 CEP16473.1 - 2.8 8.1 19.6 3.4 7.8 19.6 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Tim17 PF02466.19 CEP16474.1 - 8.6e-10 39.0 0.1 1.9e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 CEP16474.1 - 4.9e-07 30.4 2.3 4.4e-06 27.3 0.1 2.8 3 0 0 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 FeoB_C PF07664.12 CEP16474.1 - 0.069 12.9 0.1 0.64 9.7 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF1449 PF07290.11 CEP16474.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1449) FA_hydroxylase PF04116.13 CEP16475.1 - 8.9e-24 84.3 22.1 8.9e-24 84.3 22.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HlyIII PF03006.20 CEP16476.1 - 6.7e-40 137.2 16.8 9e-40 136.8 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related PSP94 PF05825.11 CEP16476.1 - 0.025 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) XPG_N PF00752.17 CEP16477.1 - 6.5e-35 119.7 0.0 2.9e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CEP16477.1 - 2.6e-25 88.6 1.0 9.7e-25 86.8 0.0 2.6 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CEP16477.1 - 0.0081 16.7 0.0 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Colicin PF01024.19 CEP16477.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Colicin pore forming domain HHH_5 PF14520.6 CEP16477.1 - 0.17 12.5 0.0 1.4 9.6 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF4349 PF14257.6 CEP16477.1 - 0.52 9.7 3.3 0.27 10.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Rubis-subs-bind PF09273.11 CEP16477.1 - 1.4 9.6 5.0 1 10.1 0.1 2.9 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding DUF883 PF05957.13 CEP16477.1 - 1.9 9.2 4.3 1.5 9.4 1.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1104 PF06518.11 CEP16477.1 - 5.1 7.5 7.4 5.3 7.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) IZUMO PF15005.6 CEP16477.1 - 5.3 7.6 8.6 0.36 11.3 0.5 3.0 3 2 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Heme_oxygenase PF01126.20 CEP16478.1 - 7.8e-51 172.8 1.3 9.9e-51 172.4 1.3 1.1 1 0 0 1 1 1 1 Heme oxygenase HMA PF00403.26 CEP16479.1 - 4.3e-12 46.3 3.9 5.7e-12 45.9 3.9 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Peptidase_Prp PF04327.12 CEP16479.1 - 0.031 14.5 0.1 0.038 14.2 0.1 1.1 1 0 0 1 1 1 0 Cysteine protease Prp Beta_helix_2 PF18835.1 CEP16479.1 - 0.66 9.8 2.8 1.4 8.7 1.5 2.0 1 1 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Mito_carr PF00153.27 CEP16480.1 - 4.4e-41 138.7 5.7 1.2e-18 66.7 0.0 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein ThiS PF02597.20 CEP16480.1 - 2.5e-08 34.4 0.0 4.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ThiS family DAO_C PF16901.5 CEP16480.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Galactosyl_T PF01762.21 CEP16481.1 - 3.8e-17 62.8 0.0 5.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 CEP16481.1 - 9.1e-13 48.5 12.8 2e-12 47.4 12.8 1.7 1 1 0 1 1 1 1 N-glycosylation protein Glyco_transf_21 PF13506.6 CEP16481.1 - 0.0056 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 LRR_4 PF12799.7 CEP16482.1 - 0.001 19.4 7.5 9.1 6.9 0.0 6.0 4 1 3 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP16482.1 - 0.003 17.9 0.8 29 5.7 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich Repeat DUF4806 PF16064.5 CEP16482.1 - 0.042 14.1 0.5 17 5.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) FlhC PF05280.11 CEP16482.1 - 0.061 13.1 1.5 0.14 11.9 1.5 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Zn-ribbon_8 PF09723.10 CEP16482.1 - 0.45 10.7 4.2 0.21 11.7 0.7 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 CEP16482.1 - 0.52 10.6 2.8 13 6.2 0.6 2.7 1 1 1 2 2 2 0 zinc-ribbon PBP1_TM PF14812.6 CEP16482.1 - 0.58 10.6 6.7 0.4 11.1 3.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1631 PF07793.11 CEP16482.1 - 0.88 7.9 4.6 1.2 7.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) LRR_6 PF13516.6 CEP16482.1 - 1 9.6 17.1 8.4 6.7 0.0 7.9 10 0 0 10 10 10 0 Leucine Rich repeat Ribosomal_L7Ae PF01248.26 CEP16483.1 - 4.9e-28 96.7 2.1 6.1e-28 96.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PAC4 PF16093.5 CEP16484.1 - 4.6e-18 65.2 0.0 6.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 RRM_1 PF00076.22 CEP16485.1 - 5.9e-25 86.9 0.0 8.7e-13 47.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP16485.1 - 2.9e-06 27.0 0.0 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CEP16485.1 - 7.6e-05 22.3 0.0 0.36 10.4 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP16485.1 - 0.014 15.5 0.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Nab6_mRNP_bdg PF10567.9 CEP16485.1 - 0.071 12.6 0.0 6.9 6.0 0.0 2.4 3 0 0 3 3 3 0 RNA-recognition motif DDE_3 PF13358.6 CEP16486.1 - 2.1e-18 66.5 0.0 9.9e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease ATP-sulfurylase PF01747.17 CEP16488.1 - 5.3e-86 287.5 0.0 7.1e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CEP16488.1 - 1.4e-55 187.3 0.0 2.5e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 CEP16488.1 - 9.1e-53 178.4 0.0 1.7e-52 177.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 CEP16488.1 - 0.0043 17.6 0.0 0.014 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP16488.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CEP16488.1 - 0.033 13.6 0.0 0.069 12.6 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Fungal_trans PF04082.18 CEP16489.1 - 1.1e-18 67.3 0.7 1.1e-18 67.3 0.7 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Allantoicase PF03561.15 CEP16489.1 - 0.019 15.0 1.0 0.037 14.0 1.0 1.5 1 0 0 1 1 1 0 Allantoicase repeat DUF4699 PF15770.5 CEP16489.1 - 0.73 9.5 9.1 1.3 8.7 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4699) 2-Hacid_dh_C PF02826.19 CEP16490.1 - 1.1e-49 168.2 0.0 2.1e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CEP16490.1 - 1.4e-36 125.1 0.0 1.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CEP16490.1 - 0.0003 21.0 0.4 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 CEP16490.1 - 0.0044 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 CEP16490.1 - 0.08 13.0 0.2 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Arrestin_N PF00339.29 CEP16491.1 - 2.3e-05 24.5 0.1 6.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PrpF PF04303.13 CEP16491.1 - 0.18 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 PrpF protein Kelch_5 PF13854.6 CEP16492.1 - 3.8e-22 77.8 0.4 0.00024 21.0 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CEP16492.1 - 7.2e-12 45.1 14.5 4.6e-05 23.3 0.0 5.5 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP16492.1 - 1.4e-10 41.0 15.4 0.0043 17.3 0.4 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CEP16492.1 - 1.1e-07 31.9 7.0 0.0035 17.6 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP16492.1 - 0.023 14.7 9.2 14 5.8 0.1 4.9 5 0 0 5 5 5 0 Kelch motif Syndecan PF01034.20 CEP16492.1 - 0.4 10.6 1.6 0.87 9.5 1.6 1.5 1 0 0 1 1 1 0 Syndecan domain Kelch_1 PF01344.25 CEP16492.1 - 7.1 6.3 12.2 13 5.5 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Y_phosphatase2 PF03162.13 CEP16493.1 - 2.4e-55 186.6 0.0 3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEP16493.1 - 2.3e-06 27.8 0.0 5.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CEP16493.1 - 0.0021 17.8 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP16493.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DAGK_acc PF00609.19 CEP16494.1 - 5.7e-14 52.7 0.0 1e-13 51.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CEP16494.1 - 1e-12 47.8 0.0 6.1e-12 45.3 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain WD40 PF00400.32 CEP16495.1 - 1.3e-28 98.6 3.0 8.2e-08 32.8 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16495.1 - 3.2e-07 30.5 0.9 0.0082 16.4 0.3 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP16495.1 - 8.9e-05 21.9 0.1 0.00064 19.1 0.1 2.4 2 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CEP16495.1 - 0.00012 21.2 1.4 0.57 9.1 0.3 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEP16495.1 - 0.00059 19.8 2.2 0.064 13.1 0.1 3.4 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 CEP16495.1 - 0.00095 19.0 0.7 0.0031 17.3 0.2 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 CEP16495.1 - 0.0087 15.1 0.5 0.82 8.6 0.0 2.7 1 1 2 3 3 3 1 Coatomer WD associated region Bacteriocin_IIi PF11758.8 CEP16495.1 - 0.026 14.3 0.3 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Nup160 PF11715.8 CEP16495.1 - 0.083 11.5 1.5 0.2 10.2 0.3 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_S19 PF00203.21 CEP16496.1 - 2.1e-33 114.0 0.5 2.8e-33 113.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 CEP16496.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH NUDIX PF00293.28 CEP16497.1 - 5.4e-16 58.8 0.5 7.6e-16 58.3 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.22 CEP16498.1 - 2.9e-12 46.1 0.0 4.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF5390 PF17365.2 CEP16499.1 - 0.0021 18.3 0.1 0.0052 17.1 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5390) RT_RNaseH PF17917.1 CEP16499.1 - 0.0026 18.0 1.1 0.05 13.9 0.1 3.1 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP16499.1 - 0.012 15.6 0.0 0.39 10.8 0.0 2.8 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase HTH_32 PF13565.6 CEP16500.1 - 1.3e-06 28.9 0.0 0.0017 19.0 0.0 2.2 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 CEP16500.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP16500.1 - 0.0022 18.0 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP16500.1 - 0.0031 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 CEP16500.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain CENP-B_N PF04218.13 CEP16500.1 - 0.0078 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 CEP16500.1 - 0.0089 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 CEP16500.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain FeoC PF09012.10 CEP16500.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator 7TMR-DISMED2 PF07696.11 CEP16500.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 7TMR-DISM extracellular 2 SWIRM-assoc_2 PF16496.5 CEP16501.1 - 3.1e-59 200.9 10.4 3.1e-59 200.9 10.4 1.6 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 CEP16501.1 - 4.4e-15 55.8 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 CEP16501.1 - 3.1e-10 40.1 0.0 7.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CEP16501.1 - 1.7e-09 37.5 5.7 4.9e-09 36.0 5.7 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CEP16501.1 - 5.8e-07 29.7 0.1 2.5e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 CEP16501.1 - 0.00033 20.4 2.7 0.00056 19.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SecM PF06558.12 CEP16501.1 - 0.011 15.9 3.6 0.022 14.8 3.6 1.5 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) SlyX PF04102.12 CEP16501.1 - 0.025 15.2 4.3 0.13 12.9 0.0 3.0 2 0 0 2 2 2 0 SlyX PPTA PF01239.22 CEP16502.1 - 1.5e-12 46.8 16.6 1.2e-05 24.9 0.5 5.2 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat MFS_1 PF07690.16 CEP16503.1 - 2.2e-30 105.8 51.9 2.8e-30 105.4 44.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Kelch_4 PF13418.6 CEP16504.1 - 8.4e-15 54.5 12.2 9.7e-06 25.5 0.1 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CEP16504.1 - 2.2e-12 46.9 6.5 0.00079 19.6 0.2 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP16504.1 - 6e-09 35.9 10.0 0.14 12.5 0.3 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CEP16504.1 - 1.7e-07 30.9 2.6 0.1 12.6 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 CEP16504.1 - 3.2e-05 23.8 0.1 0.0092 16.0 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CEP16504.1 - 0.00043 19.8 10.2 2.3 7.9 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Adeno_E3_CR2 PF02439.15 CEP16504.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Rep_1 PF01446.17 CEP16504.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Replication protein tRNA-synt_1 PF00133.22 CEP16505.1 - 7.6e-37 126.8 0.4 1.2e-25 89.9 0.2 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CEP16505.1 - 2.6e-17 62.7 0.1 7.3e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CEP16505.1 - 5e-12 46.0 0.3 1e-11 45.0 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CEP16505.1 - 6.4e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1690 PF07956.11 CEP16506.1 - 6.2e-27 94.7 8.0 7.7e-27 94.4 8.0 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Abi_2 PF07751.11 CEP16506.1 - 0.0062 16.8 1.1 0.0077 16.5 1.1 1.2 1 0 0 1 1 1 1 Abi-like protein COMPASS-Shg1 PF05205.12 CEP16506.1 - 0.012 16.3 4.4 0.012 16.3 4.4 1.5 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 CHCH PF06747.13 CEP16506.1 - 0.053 13.7 0.3 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 CHCH domain HNH_2 PF13391.6 CEP16506.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 HNH endonuclease DUF883 PF05957.13 CEP16506.1 - 0.59 10.8 5.3 0.47 11.1 3.6 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Ribosomal_L31e PF01198.19 CEP16507.1 - 9.9e-37 125.1 2.8 1.3e-36 124.7 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e ERAP1_C PF11838.8 CEP16507.1 - 0.02 14.5 0.0 0.022 14.3 0.0 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain zf-C2H2 PF00096.26 CEP16508.1 - 1.1e-15 57.1 51.3 0.00024 21.4 5.1 6.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP16508.1 - 6.3e-08 32.7 39.9 9e-05 22.7 4.0 6.2 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP16508.1 - 0.0038 17.9 13.0 0.0095 16.7 2.1 6.8 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP16508.1 - 0.017 15.1 0.6 0.017 15.1 0.6 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP16508.1 - 0.019 15.6 2.7 0.019 15.6 2.7 6.4 8 0 0 8 8 8 0 FOXP coiled-coil domain CCAP PF11105.8 CEP16508.1 - 1.2 9.1 5.9 0.78 9.7 0.4 2.6 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-C2H2_9 PF16293.5 CEP16508.1 - 2.5 8.0 9.5 23 4.9 0.2 3.8 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CDP-OH_P_transf PF01066.21 CEP16509.1 - 8.1e-11 42.5 0.0 8.1e-11 42.5 0.0 3.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Vma12 PF11712.8 CEP16509.1 - 5.1 7.2 6.3 1.5 8.9 2.7 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CNH PF00780.22 CEP16510.1 - 3.2e-59 200.8 0.0 5.9e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP16510.1 - 8.4e-35 120.6 0.6 2e-34 119.4 0.6 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP16510.1 - 2.9e-31 108.4 0.2 8.3e-31 106.9 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 CEP16510.1 - 2.5e-11 43.5 0.0 5.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Protocadherin PF08374.11 CEP16510.1 - 0.03 14.3 1.2 0.057 13.4 0.2 2.0 2 0 0 2 2 2 0 Protocadherin PheRS_DBD2 PF18554.1 CEP16510.1 - 0.12 12.3 0.1 0.44 10.6 0.1 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 2 DUF4462 PF14692.6 CEP16510.1 - 3.2 7.3 4.4 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4462) TMEM71 PF15121.6 CEP16511.1 - 0.0035 17.0 0.4 0.0057 16.3 0.4 1.4 1 0 0 1 1 1 1 TMEM71 protein family YtzH PF14165.6 CEP16513.1 - 0.42 11.0 8.9 1.2 9.5 1.5 3.2 3 1 1 4 4 4 0 YtzH-like protein PPR_2 PF13041.6 CEP16514.1 - 4e-63 209.4 27.6 2.9e-09 37.0 0.1 15.6 9 4 8 17 17 17 10 PPR repeat family PPR PF01535.20 CEP16514.1 - 4.9e-40 133.0 45.7 0.0015 18.6 0.0 19.2 21 1 0 21 21 21 12 PPR repeat PPR_long PF17177.4 CEP16514.1 - 6e-37 127.1 0.5 5.9e-10 38.9 0.0 6.9 2 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEP16514.1 - 5.2e-30 102.8 12.8 0.0014 18.3 0.0 12.4 13 0 0 13 13 13 7 PPR repeat PPR_3 PF13812.6 CEP16514.1 - 3.3e-29 100.7 22.8 1.3e-05 25.2 0.0 10.6 8 3 2 11 11 11 5 Pentatricopeptide repeat domain MRP-S27 PF10037.9 CEP16514.1 - 4.5e-05 22.5 2.7 5.1 5.8 0.0 5.4 3 1 2 6 6 6 2 Mitochondrial 28S ribosomal protein S27 RPM2 PF08579.11 CEP16514.1 - 0.019 15.3 6.5 2.1 8.8 0.1 4.5 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Wzy_C_2 PF11846.8 CEP16514.1 - 0.036 14.0 0.0 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal COX5A PF02284.16 CEP16514.1 - 0.083 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Phage_holin_2_3 PF16080.5 CEP16514.1 - 0.14 11.9 0.7 13 5.7 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Cupin_4 PF08007.12 CEP16516.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.25 CEP16517.1 - 1.7e-60 204.7 0.0 2.4e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16517.1 - 5e-30 104.6 0.0 8.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP16517.1 - 1.7e-10 41.4 1.2 5e-09 36.7 0.4 2.9 2 0 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.24 CEP16517.1 - 3.4e-06 27.0 2.7 3.4e-06 27.0 2.7 2.0 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 CEP16517.1 - 0.00032 20.1 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEP16517.1 - 0.0016 18.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RGS PF00615.19 CEP16517.1 - 0.0047 17.2 1.1 0.38 11.1 0.6 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain Kdo PF06293.14 CEP16517.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP16517.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S8 PF00082.22 CEP16518.1 - 1e-40 139.9 1.5 1.8e-40 139.1 1.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEP16518.1 - 1.3e-15 57.8 0.3 2.3e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pox_P35 PF03213.14 CEP16518.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein DDE_3 PF13358.6 CEP16519.1 - 7.5e-25 87.4 0.0 2.1e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease rve PF00665.26 CEP16519.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain LicD PF04991.13 CEP16521.1 - 0.074 13.2 0.0 0.074 13.2 0.0 1.0 1 0 0 1 1 1 0 LicD family RRM_1 PF00076.22 CEP16523.1 - 3.5e-84 276.6 3.9 3.6e-20 71.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP16523.1 - 5.1e-29 100.3 1.5 2.6e-28 98.0 1.3 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CEP16523.1 - 7.9e-14 51.3 0.4 0.033 13.8 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP16523.1 - 9.8e-07 28.8 0.8 0.36 11.0 0.0 5.0 3 2 1 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CEP16523.1 - 4e-05 23.5 1.1 5.7 7.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 CEP16523.1 - 0.0002 20.9 2.3 1.9 8.2 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease B OB domain SET_assoc PF11767.8 CEP16523.1 - 0.043 13.5 0.0 9 6.0 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RE_Eco29kI PF09517.10 CEP16523.1 - 0.16 11.6 2.8 1.7 8.2 0.1 2.9 3 0 0 3 3 3 0 Eco29kI restriction endonuclease ECH_1 PF00378.20 CEP16524.1 - 8.9e-59 198.8 0.0 1e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP16524.1 - 4.4e-29 102.0 0.0 7.7e-27 94.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HpcH_HpaI PF03328.14 CEP16525.1 - 2.4e-52 177.3 1.5 3.4e-52 176.8 1.5 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CEP16525.1 - 1.4e-18 67.2 0.0 4.2e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 CEP16525.1 - 0.0024 16.8 0.7 0.0034 16.3 0.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain B12D PF06522.11 CEP16526.1 - 5.8e-21 74.1 0.0 7.1e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LtrA PF06772.11 CEP16527.1 - 5e-27 95.0 14.4 1.3e-26 93.7 14.4 1.7 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Hydrolase_6 PF13344.6 CEP16528.1 - 4e-18 65.4 0.0 6.9e-17 61.4 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP16528.1 - 3.2e-16 59.2 0.0 4.2e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP16528.1 - 3.4e-05 24.2 0.0 0.0025 18.1 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP16528.1 - 6.8e-05 23.0 0.0 0.0085 16.2 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HSA PF07529.13 CEP16529.1 - 2.6e-14 53.3 1.8 2.6e-14 53.3 1.8 5.9 6 2 1 7 7 7 1 HSA Myb_DNA-bind_6 PF13921.6 CEP16529.1 - 2e-07 31.1 0.4 2e-07 31.1 0.4 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP16529.1 - 0.005 17.0 0.3 0.013 15.7 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_PEP_C PF04513.12 CEP16530.1 - 0.11 12.5 1.1 0.2 11.7 0.2 1.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IF-2B PF01008.17 CEP16530.1 - 0.32 10.1 2.7 0.61 9.2 2.7 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1664 PF07889.12 CEP16530.1 - 4.5 7.3 12.1 0.77 9.8 1.5 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) Spore_III_AB PF09548.10 CEP16530.1 - 7.9 6.6 10.8 16 5.6 10.8 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-binding PF00249.31 CEP16531.1 - 5.9e-94 308.1 48.9 8.6e-15 54.7 1.0 10.2 10 0 0 10 10 10 10 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP16531.1 - 1.5e-77 255.7 33.2 3.1e-12 46.6 0.0 10.1 6 3 4 10 10 10 10 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEP16531.1 - 9.4e-12 44.7 18.8 0.00026 20.8 0.0 7.3 4 2 3 7 7 7 4 Myb DNA-binding like SLIDE PF09111.10 CEP16531.1 - 2.6e-10 40.3 6.2 0.00011 22.2 0.3 6.0 4 3 2 6 6 6 3 SLIDE Rap1_C PF11626.8 CEP16531.1 - 0.005 16.9 22.2 0.021 14.9 0.1 5.8 4 1 2 6 6 6 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Imm51 PF15595.6 CEP16531.1 - 0.026 14.4 0.3 57 3.7 0.0 4.5 5 0 0 5 5 5 0 Immunity protein 51 Poxvirus_B22R_N PF13169.6 CEP16531.1 - 0.055 14.0 3.5 1.8 9.1 0.7 3.7 4 0 0 4 4 4 0 Poxvirus B22R protein N-terminal Myb_DNA-bind_2 PF08914.11 CEP16531.1 - 0.14 12.4 9.1 1.9 8.8 0.2 5.3 5 2 2 7 7 7 0 Rap1 Myb domain 6PF2K PF01591.18 CEP16532.1 - 1.2e-70 237.3 0.0 1.8e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP16532.1 - 8.4e-24 84.3 0.0 1.8e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CEP16532.1 - 5.8e-05 23.3 0.2 0.00022 21.4 0.0 2.0 3 0 0 3 3 3 1 AAA domain TFIID_30kDa PF03540.13 CEP16533.1 - 1.4e-26 92.1 0.2 2.2e-26 91.6 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 CEP16533.1 - 0.1 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RasGAP PF00616.19 CEP16534.1 - 2.7e-24 86.0 0.2 6.5e-16 58.7 0.0 2.9 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CEP16534.1 - 3.3e-19 69.4 0.5 8.9e-19 68.0 0.5 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cnd1 PF12717.7 CEP16534.1 - 5.2e-05 23.3 0.2 0.0012 18.9 0.0 3.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CRAL_TRIO PF00650.20 CEP16534.1 - 0.00026 20.8 0.3 0.00078 19.2 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.6 CEP16534.1 - 0.0036 17.2 0.0 0.034 14.0 0.0 2.7 1 1 0 1 1 1 1 Cell morphogenesis C-terminal HEAT PF02985.22 CEP16534.1 - 0.0084 16.3 4.8 3 8.3 0.3 4.1 3 0 0 3 3 3 2 HEAT repeat EBP50_C PF09007.11 CEP16535.1 - 0.1 13.6 3.0 0.063 14.3 1.2 1.5 2 0 0 2 2 2 0 EBP50, C-terminal Peptidase_M13_N PF05649.13 CEP16536.1 - 2.1e-74 251.5 2.8 3.2e-74 250.9 2.8 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEP16536.1 - 3e-71 239.3 0.0 4.6e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 CEP16536.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13_N PF05649.13 CEP16537.1 - 2.2e-73 248.2 4.0 3.3e-73 247.6 4.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEP16537.1 - 8.1e-72 241.1 0.0 1.3e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 CEP16537.1 - 0.015 15.0 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M48 Peptidase_M13 PF01431.21 CEP16538.1 - 2.3e-69 233.1 0.0 4e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CEP16538.1 - 5.3e-64 217.3 5.7 1.3e-62 212.7 5.7 2.1 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 CEP16538.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M48 Peptidase_C97 PF05903.14 CEP16540.1 - 2.2e-35 121.7 0.0 4e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain HSF_DNA-bind PF00447.17 CEP16540.1 - 5.1e-27 94.3 1.8 1.6e-26 92.7 1.8 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding IL5 PF02025.15 CEP16540.1 - 0.043 14.1 0.1 0.085 13.2 0.1 1.4 1 0 0 1 1 1 0 Interleukin 5 Bap31 PF05529.12 CEP16541.1 - 2.4e-29 101.9 0.2 4.2e-29 101.1 0.2 1.4 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region Peptidase_M13_N PF05649.13 CEP16542.1 - 1.7e-59 202.5 4.6 3.8e-53 181.5 1.1 2.9 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 CEP16542.1 - 2.6e-58 197.0 0.4 6e-58 195.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 DUF1479 PF07350.12 CEP16543.1 - 0.048 12.4 0.0 0.05 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) pPIWI_RE_Z PF18155.1 CEP16543.1 - 0.05 13.5 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z DUF816 PF05674.12 CEP16543.1 - 0.073 13.0 0.7 2.1 8.3 0.1 2.0 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF816) DUF3479 PF11965.8 CEP16544.1 - 0.096 12.8 0.0 0.14 12.2 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) zf-CCHC PF00098.23 CEP16546.1 - 0.21 11.7 0.3 0.21 11.7 0.3 2.6 3 0 0 3 3 3 0 Zinc knuckle Pap_E4 PF02711.14 CEP16546.1 - 3.5 8.6 9.5 4.1 8.4 0.4 2.7 3 0 0 3 3 3 0 E4 protein DDE_3 PF13358.6 CEP16547.1 - 1.4e-32 112.5 0.0 1.3e-27 96.4 0.0 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.19 CEP16547.1 - 2.4e-24 85.9 4.0 3.3e-20 72.5 0.2 3.4 2 1 1 3 3 3 3 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 CEP16547.1 - 8.3e-05 22.2 1.9 0.00031 20.4 1.9 2.0 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_28 PF13518.6 CEP16547.1 - 0.0025 17.9 1.0 0.006 16.7 1.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 CEP16547.1 - 0.0027 17.7 0.0 0.0092 16.0 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.6 CEP16547.1 - 0.0096 15.3 0.1 0.023 14.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 CEP16547.1 - 0.027 14.5 1.3 0.046 13.7 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 CEP16547.1 - 0.032 14.0 0.5 0.15 11.9 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain adh_short PF00106.25 CEP16548.1 - 8.8e-21 74.2 0.3 2.3e-20 72.9 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP16548.1 - 1e-11 44.8 0.2 2.8e-11 43.4 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP16548.1 - 0.004 17.1 0.0 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 KR domain DSPc PF00782.20 CEP16549.1 - 0.00012 21.9 0.0 0.00045 20.0 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP16549.1 - 0.00063 19.4 0.0 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEP16549.1 - 0.026 14.7 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate SH3_1 PF00018.28 CEP16551.1 - 2.2e-11 43.1 0.1 4.4e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP16551.1 - 1.5e-08 34.4 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP16551.1 - 5e-08 32.5 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 CEP16551.1 - 6.7e-08 32.7 3.5 1.8e-07 31.4 0.5 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Alph_Pro_TM PF09608.10 CEP16551.1 - 0.14 11.9 0.2 0.34 10.7 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) AA_permease_2 PF13520.6 CEP16552.1 - 2.8e-65 220.8 48.3 2.8e-65 220.8 48.3 1.5 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CEP16552.1 - 7e-26 90.9 41.9 1.1e-25 90.2 41.9 1.2 1 0 0 1 1 1 1 Amino acid permease DASH_Duo1 PF08651.10 CEP16553.1 - 3.2e-22 78.1 0.4 4e-22 77.8 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Duo1 ABC_tran_Xtn PF12848.7 CEP16553.1 - 0.085 12.9 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 ABC transporter HATPase_c PF02518.26 CEP16554.1 - 1e-28 100.1 1.3 2.7e-28 98.7 1.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP16554.1 - 1.2e-20 73.8 0.3 6.9e-19 68.1 0.0 3.4 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 CEP16554.1 - 1.5e-18 66.6 0.5 6.8e-18 64.5 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 CEP16554.1 - 4.3e-15 56.5 0.5 6.8e-14 52.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 CEP16554.1 - 7.9e-09 35.9 0.0 1.7e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CEP16554.1 - 5.7e-08 33.5 0.0 1.8e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 CEP16554.1 - 7.2e-08 32.1 0.0 4.3e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain GAF_3 PF13492.6 CEP16554.1 - 1.8e-06 28.3 0.0 1.2e-05 25.6 0.0 2.5 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.6 CEP16554.1 - 0.0019 18.0 0.3 0.0093 15.8 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 CEP16554.1 - 0.0039 16.5 0.0 0.97 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase NACHT PF05729.12 CEP16554.1 - 0.0046 16.9 0.0 0.021 14.7 0.0 2.3 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 CEP16554.1 - 0.017 14.4 0.1 0.087 12.0 0.1 2.2 1 1 0 1 1 1 0 NB-ARC domain Sterile PF03015.19 CEP16554.1 - 0.058 13.6 0.6 0.19 12.0 0.6 1.9 1 0 0 1 1 1 0 Male sterility protein HARP PF07443.13 CEP16554.1 - 0.92 9.2 3.0 7.9 6.2 2.4 2.5 2 0 0 2 2 2 0 HepA-related protein (HARP) Kei1 PF08552.11 CEP16555.1 - 0.085 12.7 8.1 0.21 11.5 8.1 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RVT_1 PF00078.27 CEP16557.1 - 3e-07 30.2 0.0 3.3e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase_Tyr PF07714.17 CEP16557.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Euplotes_phero PF05842.11 CEP16558.1 - 0.11 13.1 2.0 0.11 13.0 0.3 1.9 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein PNPase PF03726.14 CEP16558.1 - 0.14 12.6 7.8 2 9.0 0.2 2.8 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NUDIX PF00293.28 CEP16561.1 - 6.7e-11 42.3 0.0 8.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain SRP-alpha_N PF04086.13 CEP16563.1 - 0.28 11.1 27.4 0.33 10.8 27.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.13 CEP16563.1 - 3.9 7.0 30.4 4.8 6.7 30.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Swi6_N PF18530.1 CEP16563.1 - 5.8 7.1 11.1 0.44 10.7 3.9 2.7 2 1 0 2 2 2 0 Swi6 N-terminal domain Methyltransf_8 PF05148.15 CEP16564.1 - 1.9e-79 266.6 3.6 8.8e-79 264.4 0.1 2.3 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CEP16564.1 - 1e-07 32.5 0.1 7.4e-07 29.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP16564.1 - 2.3e-06 28.2 0.1 0.00037 21.2 0.1 3.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP16564.1 - 0.0001 21.9 0.3 0.0046 16.5 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CEP16564.1 - 0.00012 21.5 0.1 0.00035 20.0 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CEP16564.1 - 0.00068 19.5 2.0 0.035 13.9 0.2 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEP16564.1 - 0.035 14.0 3.3 0.34 10.9 0.0 3.2 3 1 1 4 4 4 0 Methyltransferase domain Methyltransf_32 PF13679.6 CEP16564.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain DNA_ligase_A_M PF01068.21 CEP16565.1 - 2.5e-18 66.5 1.3 4.4e-18 65.7 1.3 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Methyltransf_11 PF08241.12 CEP16565.1 - 2.3e-14 53.8 0.0 8.8e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP16565.1 - 2.4e-12 46.9 0.1 8.7e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP16565.1 - 4.3e-12 46.6 0.0 2.2e-11 44.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP16565.1 - 8.3e-07 29.7 0.0 2.8e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain DNA_ligase_OB_2 PF14743.6 CEP16565.1 - 8.8e-07 28.9 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain RNA_ligase PF09414.10 CEP16565.1 - 1.6e-06 28.6 0.3 2.9e-06 27.7 0.3 1.5 1 0 0 1 1 1 1 RNA ligase NodS PF05401.11 CEP16565.1 - 0.00026 20.7 0.0 0.00061 19.5 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) mRNA_cap_enzyme PF01331.19 CEP16565.1 - 0.0024 17.7 1.3 0.012 15.4 1.2 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_N PF04675.14 CEP16565.1 - 0.0041 17.5 0.0 0.061 13.6 0.0 2.3 1 1 1 2 2 2 1 DNA ligase N terminus MTS PF05175.14 CEP16565.1 - 0.05 13.1 0.0 0.23 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain HSP70 PF00012.20 CEP16566.1 - 7.8e-105 351.3 4.8 7.8e-105 351.3 4.8 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEP16566.1 - 5.4e-14 51.8 1.3 9.5e-14 50.9 0.8 1.6 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 CEP16566.1 - 8.1e-05 21.8 0.3 0.085 11.9 0.1 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Raco_middle PF17651.1 CEP16566.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 RACo middle region Metallopep PF12044.8 CEP16567.1 - 4.8e-132 440.6 0.0 6e-132 440.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CEP16567.1 - 3.5e-07 30.2 0.1 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Jacalin-like lectin domain Peptidase_M66 PF10462.9 CEP16567.1 - 0.11 11.4 0.3 0.22 10.4 0.3 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 CEP16567.1 - 0.17 12.4 0.1 0.47 11.0 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CRAL_TRIO PF00650.20 CEP16569.1 - 2.4e-14 53.4 0.0 5.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF4601 PF15373.6 CEP16569.1 - 0.061 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) GATA PF00320.27 CEP16570.1 - 5.5e-14 51.5 4.7 1.1e-13 50.5 4.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF5339 PF17274.2 CEP16570.1 - 0.051 14.4 1.8 0.096 13.5 1.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5339) RNA_pol_Rpc4 PF05132.14 CEP16570.1 - 0.14 12.6 1.8 0.24 11.8 1.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-3CxxC PF13695.6 CEP16570.1 - 0.15 12.6 6.0 0.41 11.1 6.0 1.8 1 1 0 1 1 1 0 Zinc-binding domain TPR_14 PF13428.6 CEP16571.1 - 3.9e-16 58.4 21.3 0.0035 18.0 0.1 11.5 6 4 6 12 12 12 3 Tetratricopeptide repeat Suf PF05843.14 CEP16571.1 - 2e-14 54.3 12.5 0.019 14.9 0.1 7.2 3 2 4 8 8 8 5 Suppressor of forked protein (Suf) TPR_2 PF07719.17 CEP16571.1 - 2e-06 27.4 22.8 0.99 9.7 0.1 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CEP16571.1 - 2e-06 27.1 8.2 0.0063 15.7 0.2 5.6 2 2 0 5 5 5 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 CEP16571.1 - 3.5e-06 27.4 8.4 2 9.0 0.1 7.0 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 CEP16571.1 - 5.1e-06 26.3 17.7 0.0021 18.1 0.0 8.9 11 0 0 11 11 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEP16571.1 - 9.3e-05 22.4 12.3 1.1 9.3 0.0 6.5 7 1 1 8 8 8 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CEP16571.1 - 0.0003 21.0 14.1 0.021 15.1 0.0 6.6 6 2 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP16571.1 - 0.0019 18.5 10.2 29 5.4 0.0 8.5 9 1 0 9 9 9 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 CEP16571.1 - 0.01 15.9 0.2 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein ArdA PF07275.11 CEP16571.1 - 0.031 14.9 2.4 0.36 11.4 0.3 3.2 3 0 0 3 3 3 0 Antirestriction protein (ArdA) CKAP2_C PF15297.6 CEP16571.1 - 0.039 13.1 0.3 0.8 8.7 0.0 2.8 3 1 0 3 3 3 0 Cytoskeleton-associated protein 2 C-terminus TPR_16 PF13432.6 CEP16571.1 - 0.065 13.9 8.3 1.7 9.4 0.0 5.3 5 2 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 CEP16571.1 - 0.072 12.5 9.1 0.088 12.2 0.1 4.4 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CEP16571.1 - 0.3 11.8 22.4 22 6.0 0.0 8.4 9 1 1 10 10 9 0 Tetratricopeptide repeat DALR_1 PF05746.15 CEP16571.1 - 0.69 10.1 3.3 3.4 7.9 0.0 3.2 3 0 0 3 3 3 0 DALR anticodon binding domain MIT PF04212.18 CEP16571.1 - 0.83 9.8 4.0 2.7 8.1 0.0 4.0 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Exonuc_VII_S PF02609.16 CEP16571.1 - 0.86 9.7 4.4 4.3 7.5 0.1 4.3 5 0 0 5 5 5 0 Exonuclease VII small subunit TPR_1 PF00515.28 CEP16571.1 - 1.7 8.6 16.2 71 3.5 0.2 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat SH3_1 PF00018.28 CEP16572.1 - 8.5e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP16572.1 - 5.3e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 CEP16572.1 - 0.0018 18.8 0.0 0.67 10.6 0.0 3.2 2 1 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Med26_C PF15693.5 CEP16573.1 - 0.0047 17.1 2.6 0.0073 16.5 2.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 26 C-terminal DUF4715 PF15835.5 CEP16573.1 - 0.051 13.6 0.1 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) Na_H_Exchanger PF00999.21 CEP16575.1 - 1.2e-64 218.5 30.5 1.4e-64 218.2 30.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 CEP16575.1 - 1.3 8.6 3.4 18 4.9 0.7 2.9 2 0 0 2 2 2 0 PepSY-associated TM region DUF2062 PF09835.9 CEP16575.1 - 7.5 6.4 14.0 6.3 6.6 0.4 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF2838 PF10998.8 CEP16576.1 - 7.8e-42 142.0 8.8 7.8e-42 142.0 8.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) ApoC-I PF04691.12 CEP16576.1 - 0.031 14.2 3.2 0.082 12.9 3.2 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) COG5 PF10392.9 CEP16576.1 - 0.038 14.1 0.5 0.072 13.3 0.5 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Matrilin_ccoil PF10393.9 CEP16576.1 - 1.2 9.0 3.2 11 6.0 0.9 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Choline_kinase PF01633.20 CEP16577.1 - 6.7e-57 192.5 0.3 1.3e-56 191.6 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CEP16577.1 - 7.6e-07 29.3 0.0 9.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family LST1 PF05083.13 CEP16578.1 - 0.017 15.4 0.4 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 LST-1 protein LYTB PF02401.18 CEP16578.1 - 0.024 13.9 0.2 0.11 11.8 0.0 1.8 1 1 0 2 2 2 0 LytB protein LapA_dom PF06305.11 CEP16578.1 - 0.43 10.4 2.5 1.3 8.9 2.5 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RhoGAP PF00620.27 CEP16580.1 - 3.3e-48 163.4 0.0 8.7e-48 162.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CEP16580.1 - 2e-08 34.0 4.5 2e-08 34.0 4.5 3.6 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 CEP16580.1 - 2.8e-08 33.8 8.1 2.8e-08 33.8 8.1 3.3 3 0 0 3 3 3 2 LIM domain Cyclin_C PF02984.19 CEP16580.1 - 0.022 14.8 0.2 0.091 12.9 0.2 2.0 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF3682 PF12446.8 CEP16580.1 - 0.037 14.5 0.2 0.037 14.5 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3682) TolA_bind_tri PF16331.5 CEP16581.1 - 0.023 14.8 3.6 0.06 13.4 3.7 1.7 1 1 1 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 CEP16581.1 - 0.049 14.1 4.9 0.1 13.1 4.9 1.5 1 1 0 1 1 1 0 Cell division protein ZapB PCRF PF03462.18 CEP16581.1 - 0.13 12.1 2.2 0.14 12.0 2.2 1.0 1 0 0 1 1 1 0 PCRF domain Ribosomal_L15e PF00827.17 CEP16582.1 - 2e-86 288.6 8.7 3.3e-86 287.9 8.7 1.3 1 0 0 1 1 1 1 Ribosomal L15 F-box-like PF12937.7 CEP16582.1 - 5.2e-10 39.1 8.6 1.5e-09 37.6 3.6 3.8 4 0 0 4 4 4 1 F-box-like LRR_6 PF13516.6 CEP16582.1 - 6.2e-06 25.9 14.2 3.1 8.1 0.0 9.8 11 0 0 11 11 11 1 Leucine Rich repeat F-box PF00646.33 CEP16582.1 - 5.8e-05 22.9 4.1 0.00047 20.0 0.3 3.8 4 0 0 4 4 4 1 F-box domain LRR_4 PF12799.7 CEP16582.1 - 9.4e-05 22.7 15.1 12 6.5 0.0 7.6 6 2 2 9 9 9 2 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 CEP16582.1 - 0.031 13.9 1.0 2 8.1 0.0 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF1699) TruB_N PF01509.18 CEP16583.1 - 4.5e-44 150.4 0.0 1e-43 149.3 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CEP16583.1 - 3.2e-08 33.6 0.0 8.2e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF4381 PF14316.6 CEP16583.1 - 0.002 18.4 0.2 0.0037 17.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) OAD_gamma PF04277.13 CEP16583.1 - 0.0034 17.9 1.5 0.0068 17.0 1.5 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain OSTbeta PF15048.6 CEP16583.1 - 0.0099 16.0 1.2 0.017 15.3 0.7 1.5 1 1 0 1 1 1 1 Organic solute transporter subunit beta protein ASFV_J13L PF05568.11 CEP16583.1 - 0.013 15.3 0.3 0.022 14.5 0.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Phage_holin_3_6 PF07332.11 CEP16583.1 - 0.02 14.9 1.1 0.033 14.2 1.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM154 PF15102.6 CEP16583.1 - 0.02 14.8 1.1 0.049 13.5 1.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family ABC_membrane PF00664.23 CEP16583.1 - 0.02 14.5 0.2 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region V_ATPase_I PF01496.19 CEP16583.1 - 0.021 12.8 1.1 0.03 12.3 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EphA2_TM PF14575.6 CEP16583.1 - 0.025 15.4 1.8 0.057 14.3 1.9 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.8 CEP16583.1 - 0.036 14.1 0.9 0.069 13.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF2140 PF09911.9 CEP16583.1 - 0.043 13.4 0.5 0.094 12.2 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF5385 PF17359.2 CEP16583.1 - 0.043 13.4 0.3 0.091 12.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2681 PF10883.8 CEP16583.1 - 0.074 13.5 1.1 0.18 12.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SIT PF15330.6 CEP16583.1 - 0.093 13.2 1.9 0.27 11.7 0.8 2.2 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT OATP PF03137.20 CEP16583.1 - 0.096 11.0 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.6 CEP16583.1 - 0.097 11.4 0.4 0.14 10.9 0.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sugar_tr PF00083.24 CEP16583.1 - 0.1 11.4 0.3 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 CEP16583.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Phage_holin_6_1 PF09682.10 CEP16583.1 - 0.12 12.8 5.2 0.33 11.4 5.2 1.7 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Shisa PF13908.6 CEP16583.1 - 0.23 11.7 1.8 0.31 11.3 1.1 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 CEP16583.1 - 0.31 12.0 4.5 1.9 9.5 4.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Vpu PF00558.19 CEP16583.1 - 0.48 10.2 5.0 1.1 9.1 5.0 1.5 1 0 0 1 1 1 0 Vpu protein DUF4446 PF14584.6 CEP16583.1 - 2.6 8.0 4.6 1.2 9.1 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FeoB_associated PF12669.7 CEP16583.1 - 3.2 8.2 7.0 5.9 7.4 7.0 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ribosomal_L34e PF01199.18 CEP16585.1 - 1.4e-45 153.5 6.0 1.8e-45 153.2 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e NUC153 PF08159.12 CEP16586.1 - 2.6e-15 55.9 14.1 9.5e-14 50.9 0.7 4.0 3 0 0 3 3 3 3 NUC153 domain ATP-synt_J PF04911.12 CEP16586.1 - 0.74 9.4 2.8 5.3 6.7 0.0 3.2 3 0 0 3 3 3 0 ATP synthase j chain GCR1_C PF12550.8 CEP16587.1 - 0.00077 19.7 0.6 0.00077 19.7 0.6 2.0 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes ParB PF08775.10 CEP16587.1 - 0.086 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ParB family TRAF_BIRC3_bd PF16673.5 CEP16587.1 - 0.11 12.3 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain RRM_1 PF00076.22 CEP16588.1 - 2e-37 126.8 0.1 6.3e-21 74.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ER PF01133.17 CEP16588.1 - 2.3e-08 33.9 0.0 7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Enhancer of rudimentary DUF2722 PF10846.8 CEP16588.1 - 0.00057 19.0 8.3 0.00057 19.0 8.3 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 CEP16588.1 - 0.013 15.6 2.7 0.013 15.6 2.7 5.4 4 1 1 6 6 6 0 Unstructured region C-term to UIM in Ataxin3 PABP PF00658.18 CEP16588.1 - 0.017 15.3 6.7 0.075 13.2 0.0 3.2 3 0 0 3 3 3 0 Poly-adenylate binding protein, unique domain SR-25 PF10500.9 CEP16588.1 - 1.5 8.4 18.2 0.66 9.5 1.2 2.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Lipase_3 PF01764.25 CEP16589.1 - 3.1e-19 69.3 0.0 5.1e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CEP16589.1 - 0.0033 18.1 0.0 0.0055 17.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Utp21 PF04192.12 CEP16590.1 - 2.9e-71 239.7 1.0 5.6e-71 238.7 1.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CEP16590.1 - 9.3e-31 105.4 20.4 9.9e-08 32.5 0.5 10.4 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16590.1 - 2.7e-20 72.4 1.1 1.1e-05 25.7 0.0 8.0 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP16590.1 - 5.1e-08 32.0 11.8 0.0069 15.1 0.2 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CEP16590.1 - 4.8e-05 22.3 1.2 0.033 12.9 0.2 3.1 2 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 CEP16590.1 - 0.00018 21.0 0.3 0.49 9.7 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 CEP16590.1 - 0.012 15.2 0.0 2.8 7.4 0.0 3.5 2 1 1 3 3 3 0 PQQ-like domain Cytochrom_D1 PF02239.16 CEP16590.1 - 0.014 14.0 0.1 0.4 9.2 0.0 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CEP16590.1 - 0.031 13.2 4.9 1.6 7.6 0.0 4.1 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BRE1 PF08647.11 CEP16591.1 - 0.22 11.6 7.2 0.33 11.1 6.0 1.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase SR-25 PF10500.9 CEP16591.1 - 2.3 7.8 21.1 3.6 7.1 21.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PHD PF00628.29 CEP16592.1 - 4e-06 26.6 14.5 1.1e-05 25.3 14.5 1.8 1 0 0 1 1 1 1 PHD-finger GATA PF00320.27 CEP16592.1 - 7.3e-05 22.3 4.6 0.00017 21.1 4.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-HC5HC2H PF13771.6 CEP16592.1 - 0.13 12.5 10.1 0.08 13.2 6.1 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PAP_assoc PF03828.19 CEP16593.1 - 1.5e-08 34.7 0.0 5.7e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CEP16593.1 - 2.2e-07 31.1 0.0 5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CEP16593.1 - 0.00065 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 CEP16594.1 - 6.7e-51 173.2 0.1 1.4e-50 172.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16594.1 - 1.9e-23 83.1 0.0 3.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEP16594.1 - 0.002 17.2 0.1 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CEP16594.1 - 0.031 13.9 0.4 0.6 9.7 0.4 2.3 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CEP16594.1 - 0.88 8.3 15.5 7 5.3 15.5 2.2 1 1 0 1 1 1 0 Fungal protein kinase Acyltransf_C PF16076.5 CEP16595.1 - 7.7e-15 54.8 0.9 1.3e-14 54.0 0.9 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CEP16595.1 - 3.7e-08 33.1 0.0 5.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TP_methylase PF00590.20 CEP16596.1 - 6e-44 150.5 0.1 1e-43 149.8 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 CEP16596.1 - 3.3e-21 74.7 0.1 6.5e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 CEP16596.1 - 4e-12 46.5 0.0 1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CEP16596.1 - 1.9e-10 40.0 0.5 3.6e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CTP_synth_N PF06418.14 CEP16597.1 - 8.7e-124 412.1 0.1 1.1e-123 411.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CEP16597.1 - 6.6e-61 205.4 0.0 1e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEP16597.1 - 2.9e-05 23.9 0.0 7.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 AAA PF00004.29 CEP16598.1 - 1.3e-40 138.8 0.0 1.5e-23 83.7 0.0 3.5 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP16598.1 - 1.8e-14 53.3 0.1 8.8e-12 44.6 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CEP16598.1 - 6.5e-13 49.4 2.9 0.00057 20.3 0.0 4.5 3 2 1 5 5 4 2 AAA ATPase domain DUF815 PF05673.13 CEP16598.1 - 1.7e-09 37.2 0.0 0.00069 18.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 CEP16598.1 - 3.8e-09 36.7 0.0 0.00082 19.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CEP16598.1 - 7.2e-09 36.0 0.2 0.027 14.8 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_7 PF12775.7 CEP16598.1 - 4.1e-07 29.7 0.0 0.035 13.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 CEP16598.1 - 1.4e-06 27.8 0.3 0.0037 16.6 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.17 CEP16598.1 - 2.4e-06 27.4 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CEP16598.1 - 3.7e-06 27.1 0.0 0.018 15.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CEP16598.1 - 6.9e-06 25.8 0.7 0.18 11.3 0.0 3.3 3 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 CEP16598.1 - 7.2e-06 25.8 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 CEP16598.1 - 8.4e-06 25.6 0.2 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CEP16598.1 - 8.7e-06 26.3 0.1 0.18 12.3 0.0 2.8 2 2 0 2 2 2 2 ABC transporter NACHT PF05729.12 CEP16598.1 - 9.9e-06 25.6 0.2 0.51 10.3 0.0 3.4 3 0 0 3 3 3 2 NACHT domain RuvB_N PF05496.12 CEP16598.1 - 1.4e-05 24.9 0.0 0.00022 21.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CEP16598.1 - 1.5e-05 25.3 0.0 0.09 13.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CEP16598.1 - 2.9e-05 24.6 0.1 0.17 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CEP16598.1 - 3e-05 24.0 0.0 0.29 11.1 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CEP16598.1 - 3.4e-05 23.3 0.0 0.076 12.3 0.0 2.4 2 0 0 2 2 2 2 KaiC Mg_chelatase PF01078.21 CEP16598.1 - 4.2e-05 23.0 0.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CEP16598.1 - 5.3e-05 22.6 0.1 0.0043 16.3 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 CEP16598.1 - 7.3e-05 22.6 0.1 0.083 12.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CEP16598.1 - 0.00011 22.3 0.0 0.25 11.4 0.0 3.3 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 CEP16598.1 - 0.00015 21.9 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 CEP16598.1 - 0.00021 20.5 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_29 PF13555.6 CEP16598.1 - 0.00029 20.5 0.0 0.34 10.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 CEP16598.1 - 0.00075 19.8 0.7 1.6 9.1 0.1 2.7 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 CEP16598.1 - 0.00078 19.0 0.1 0.096 12.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 CEP16598.1 - 0.00095 19.4 0.2 0.43 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CEP16598.1 - 0.0012 18.9 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CEP16598.1 - 0.002 17.5 2.0 1 8.5 0.1 2.5 3 0 0 3 3 2 2 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 CEP16598.1 - 0.0033 16.8 0.0 0.5 9.7 0.0 2.7 3 0 0 3 3 2 1 Bacterial TniB protein Rad17 PF03215.15 CEP16598.1 - 0.0043 17.0 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_11 PF13086.6 CEP16598.1 - 0.007 16.2 0.1 1 9.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEP16598.1 - 0.01 15.8 0.1 0.36 10.7 0.0 2.6 3 0 0 3 3 2 0 RsgA GTPase NB-ARC PF00931.22 CEP16598.1 - 0.016 14.4 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Torsin PF06309.11 CEP16598.1 - 0.022 14.9 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Torsin AAA_3 PF07726.11 CEP16598.1 - 0.022 14.6 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 CEP16598.1 - 0.024 13.8 0.1 5 6.2 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.25 CEP16598.1 - 0.026 14.2 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 CEP16598.1 - 0.028 14.7 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CEP16598.1 - 0.039 14.5 0.3 8.5 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain Bac_DnaA PF00308.18 CEP16598.1 - 0.04 13.7 0.3 8.2 6.2 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein PIF1 PF05970.14 CEP16598.1 - 0.055 12.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.17 CEP16598.1 - 0.062 12.4 0.0 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.21 CEP16598.1 - 0.082 12.6 0.1 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase CPT PF07931.12 CEP16598.1 - 0.11 12.4 0.1 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_32 PF13654.6 CEP16599.1 - 0.01 14.7 0.9 1.9 7.2 0.5 2.6 3 0 0 3 3 3 0 AAA domain DUF148 PF02520.17 CEP16599.1 - 6.4 6.9 17.3 15 5.8 2.7 3.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 SUIM_assoc PF16619.5 CEP16599.1 - 8.7 6.5 12.7 0.17 11.9 4.4 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 F-box-like PF12937.7 CEP16600.1 - 5.1e-08 32.7 0.0 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like DDE_3 PF13358.6 CEP16601.1 - 7.9e-26 90.6 0.0 2.2e-24 85.9 0.0 2.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP16601.1 - 0.0029 17.7 0.2 0.0074 16.4 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP16601.1 - 0.01 15.6 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 CEP16601.1 - 0.057 13.4 0.2 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix FANC_SAP PF18081.1 CEP16601.1 - 0.069 13.3 0.0 0.83 9.9 0.0 2.6 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain Chitin_synth_1 PF01644.17 CEP16602.1 - 2.4e-67 226.0 0.3 1.6e-66 223.3 0.3 2.2 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CEP16602.1 - 2.6e-30 104.2 0.1 9.7e-30 102.3 0.1 2.1 2 0 0 2 2 2 1 Chitin synthase N-terminal SNAP PF14938.6 CEP16602.1 - 8.1e-30 104.2 12.1 1.3e-29 103.5 12.1 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Chitin_synth_2 PF03142.15 CEP16602.1 - 2.4e-25 89.2 0.2 2.5e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP16602.1 - 4e-05 23.6 3.3 4e-05 23.6 3.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 TPR_14 PF13428.6 CEP16602.1 - 0.059 14.2 0.6 31 5.7 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat NepR PF18557.1 CEP16604.1 - 0.0016 18.0 0.6 0.0028 17.3 0.0 1.7 2 0 0 2 2 2 1 Anti-sigma factor NepR ARD PF03079.14 CEP16605.1 - 2.5e-50 170.7 1.4 3e-50 170.5 1.4 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CEP16605.1 - 6.9e-09 35.3 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CEP16605.1 - 6.9e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CEP16605.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin EF-hand_1 PF00036.32 CEP16606.1 - 1.9e-41 136.6 10.5 1.8e-10 39.6 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP16606.1 - 1.2e-34 118.5 3.3 6.4e-19 68.2 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEP16606.1 - 5.2e-31 106.3 10.9 3.3e-14 52.4 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CEP16606.1 - 1.1e-30 102.9 5.1 2.7e-09 36.2 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEP16606.1 - 8.3e-25 85.1 8.0 2.4e-06 26.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEP16606.1 - 2.9e-14 53.1 0.1 4.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CEP16606.1 - 2.5e-10 40.7 0.5 0.00011 22.5 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP16606.1 - 1.5e-08 34.5 1.3 0.001 19.0 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 CEP16606.1 - 1.6e-05 24.9 2.9 2e-05 24.6 0.5 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 CEP16606.1 - 6e-05 23.9 0.0 0.0058 17.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CEP16606.1 - 0.00047 20.3 3.6 0.015 15.5 0.1 3.0 1 1 1 2 2 2 1 Dockerin type I domain TerB PF05099.13 CEP16606.1 - 0.00067 19.6 1.1 0.34 10.9 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.13 CEP16606.1 - 0.0008 19.4 0.6 1.2 9.0 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 CEP16606.1 - 0.0019 18.9 0.5 3.1 8.6 0.0 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 CEP16606.1 - 0.0042 17.4 2.5 0.59 10.5 0.2 2.9 3 1 0 3 3 3 1 RNA polymerase Rpb4 UPF0154 PF03672.13 CEP16606.1 - 0.005 16.8 0.9 0.18 11.9 0.0 2.9 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0154) PY_rept_46 PF09689.10 CEP16606.1 - 0.0053 17.3 1.1 2.5 8.7 0.0 3.0 2 1 1 3 3 3 1 Plasmodium yoelii repeat (PY_rept_46) DUF5580 PF17743.1 CEP16606.1 - 0.0098 14.5 0.0 0.0099 14.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Fe_hyd_lg_C PF02906.14 CEP16606.1 - 0.013 15.2 0.4 0.031 13.9 0.4 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SurA_N_2 PF13623.6 CEP16606.1 - 0.018 14.9 1.3 0.69 9.8 0.3 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF1811 PF08838.10 CEP16606.1 - 0.025 14.8 0.6 4.8 7.5 0.1 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1811) DUF2267 PF10025.9 CEP16606.1 - 0.029 14.6 0.0 0.086 13.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) PhageMin_Tail PF10145.9 CEP16606.1 - 0.041 13.7 0.7 0.077 12.9 0.1 1.7 2 0 0 2 2 2 0 Phage-related minor tail protein DUF853 PF05872.12 CEP16606.1 - 0.082 11.5 0.0 0.18 10.3 0.0 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 CEP16606.1 - 0.092 13.1 0.2 8.6 6.8 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Prok-E2_A PF14457.6 CEP16607.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A TRAM_LAG1_CLN8 PF03798.16 CEP16608.1 - 1e-39 136.4 27.6 1e-39 136.4 27.6 1.8 2 0 0 2 2 2 1 TLC domain DUF4719 PF15843.5 CEP16608.1 - 0.4 10.8 0.8 9.1 6.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) RVT_1 PF00078.27 CEP16609.1 - 8e-13 48.4 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 CEP16610.1 - 1.4e-08 34.7 39.8 0.00037 20.8 1.3 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP16610.1 - 1.1e-06 28.8 15.2 0.00014 22.1 3.4 5.9 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP16610.1 - 0.05 14.5 2.9 0.05 14.5 2.9 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP16610.1 - 0.45 11.2 0.1 0.45 11.2 0.1 6.6 6 1 1 7 7 7 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CEP16610.1 - 3.7 7.7 13.5 2.6 8.2 3.4 3.3 2 1 1 3 3 3 0 Aberrant zinc-finger GSH_synth_ATP PF03917.17 CEP16611.1 - 3.2e-137 457.3 0.0 3.8e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CEP16611.1 - 4.6e-36 123.4 0.0 9e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase LOH1CR12 PF10158.9 CEP16611.1 - 0.032 14.3 0.4 0.066 13.2 0.4 1.4 1 0 0 1 1 1 0 Tumour suppressor protein ThrE PF06738.12 CEP16612.1 - 4.1e-51 173.7 17.7 6.2e-48 163.3 2.0 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CEP16612.1 - 0.017 15.3 24.9 0.036 14.2 7.7 2.4 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE B-block_TFIIIC PF04182.12 CEP16613.1 - 3.8e-15 55.8 0.3 1.8e-14 53.7 0.3 2.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 CEP16613.1 - 0.00013 21.4 0.1 0.0025 17.3 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CEP16613.1 - 0.002 18.0 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 MarR family MarR PF01047.22 CEP16613.1 - 0.023 14.6 4.1 0.024 14.6 0.0 3.3 4 0 0 4 4 4 0 MarR family DUF2118 PF09891.9 CEP16613.1 - 0.03 14.3 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HTH_27 PF13463.6 CEP16613.1 - 0.049 14.1 0.1 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_5 PF01022.20 CEP16613.1 - 0.093 12.6 0.1 0.54 10.2 0.1 2.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RNA_pol_Rpb2_5 PF04567.17 CEP16613.1 - 0.15 12.6 0.0 0.73 10.4 0.0 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 polyprenyl_synt PF00348.17 CEP16614.1 - 1.1e-46 159.0 0.0 1.6e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.19 CEP16614.1 - 0.0062 16.1 0.1 0.039 13.4 0.1 2.0 1 1 0 1 1 1 1 Squalene/phytoene synthase HEPPP_synt_1 PF07307.11 CEP16614.1 - 0.023 14.3 0.2 0.047 13.3 0.1 1.6 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RPN1_C PF18051.1 CEP16614.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal DDE_Tnp_1_7 PF13843.6 CEP16615.1 - 1.7e-09 37.4 0.0 4.5e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 Inj_translocase PF16928.5 CEP16616.1 - 0.067 12.6 2.4 0.1 12.0 2.4 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome ERp29 PF07749.12 CEP16616.1 - 0.16 12.9 0.6 0.38 11.7 0.6 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain SUIM_assoc PF16619.5 CEP16616.1 - 0.4 10.8 8.2 2.1 8.5 8.2 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ysc84 PF04366.12 CEP16617.1 - 7.5e-32 109.8 0.8 1.2e-31 109.2 0.8 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CEP16617.1 - 8.1e-14 51.0 0.1 1.7e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP16617.1 - 1.4e-11 44.0 0.1 2.6e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP16617.1 - 1.1e-09 37.8 0.0 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Enkurin PF13864.6 CEP16618.1 - 0.0057 17.1 20.5 0.0057 17.1 20.5 5.2 1 1 2 3 3 3 1 Calmodulin-binding CENP-F_leu_zip PF10473.9 CEP16618.1 - 0.0094 16.0 9.2 0.0094 16.0 9.2 4.6 2 2 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Imm43 PF15570.6 CEP16618.1 - 0.015 15.3 1.3 0.054 13.5 1.3 2.0 1 0 0 1 1 1 0 Immunity protein 43 UPF0242 PF06785.11 CEP16618.1 - 0.57 10.2 63.1 1.5 8.9 15.4 3.6 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus TetR_C_24 PF17932.1 CEP16618.1 - 6.3 7.1 7.5 3.5 7.9 4.7 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L13 PF00572.18 CEP16619.1 - 3.6e-10 40.2 0.1 3.4e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 MFS_1 PF07690.16 CEP16621.1 - 6.5e-35 120.7 33.4 1.9e-34 119.2 34.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1566 PF07603.11 CEP16621.1 - 0.039 14.3 0.2 0.072 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) VirE1 PF12189.8 CEP16621.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Single-strand DNA-binding protein TcpE PF12648.7 CEP16621.1 - 3.7 8.1 9.2 3.9 8.1 0.8 3.1 2 1 1 3 3 3 0 TcpE family Vps35 PF03635.17 CEP16622.1 - 0 1050.5 7.3 0 1050.3 7.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 BUD22 PF09073.10 CEP16622.1 - 0.31 10.3 24.7 0.53 9.6 24.7 1.2 1 0 0 1 1 1 0 BUD22 DDHD PF02862.17 CEP16622.1 - 0.42 10.8 2.1 0.86 9.7 2.1 1.5 1 0 0 1 1 1 0 DDHD domain SURF2 PF05477.11 CEP16622.1 - 4.1 7.0 18.1 0.93 9.1 14.4 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) VWA_2 PF13519.6 CEP16623.1 - 4.1e-25 88.5 3.5 2.6e-24 85.9 0.1 3.3 2 2 2 4 4 4 1 von Willebrand factor type A domain Ssl1 PF04056.14 CEP16623.1 - 2.4e-08 34.0 0.9 7.4e-08 32.4 0.0 2.1 2 1 1 3 3 3 1 Ssl1-like UIM PF02809.20 CEP16623.1 - 2.6e-07 30.1 31.0 0.0004 20.1 2.4 5.3 5 0 0 5 5 5 3 Ubiquitin interaction motif Integrase_H2C2 PF17921.1 CEP16624.1 - 4.4e-07 29.9 0.1 9.1e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CEP16624.1 - 1.7e-05 24.8 0.3 5.5e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CEP16624.1 - 0.00015 21.9 0.6 0.00039 20.6 0.6 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 CEP16624.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase SgrT PF15894.5 CEP16627.1 - 0.21 11.6 0.4 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT PIF1 PF05970.14 CEP16628.1 - 5.9e-05 22.4 0.1 8.2e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP16628.1 - 7.4e-05 22.5 0.0 9.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEP16628.1 - 0.00056 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CEP16628.1 - 0.0024 18.3 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 CEP16628.1 - 0.005 16.3 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 CEP16628.1 - 0.0089 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP16628.1 - 0.029 13.6 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CEP16628.1 - 0.047 14.0 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP16628.1 - 0.099 12.5 1.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 CEP16628.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin pPIWI_RE_Z PF18155.1 CEP16629.1 - 0.11 12.4 0.6 0.13 12.1 0.6 1.1 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Secretin_N_2 PF07655.13 CEP16629.1 - 0.31 11.6 4.4 0.49 11.0 4.4 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Remorin_N PF03766.13 CEP16632.1 - 4.8 7.3 7.0 5.3 7.2 0.4 2.7 1 1 1 2 2 2 0 Remorin, N-terminal region EVE PF01878.18 CEP16633.1 - 0.055 13.5 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 EVE domain Lumazine_bd_2 PF12893.7 CEP16634.1 - 0.077 13.7 0.0 0.097 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative lumazine-binding Mitoc_L55 PF09776.9 CEP16636.1 - 0.059 13.1 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 SKIP_SNW PF02731.15 CEP16637.1 - 8.4e-73 243.3 2.4 8.4e-73 243.3 2.4 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM199X PF15814.5 CEP16637.1 - 0.81 8.7 11.1 1.3 8.0 11.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X DIE2_ALG10 PF04922.12 CEP16638.1 - 1.9e-64 218.4 12.1 2.2e-64 218.2 12.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family KH_1 PF00013.29 CEP16639.1 - 2.4e-75 248.3 20.9 1.1e-12 47.5 2.1 9.2 9 0 0 9 9 9 8 KH domain SLS PF14611.6 CEP16639.1 - 1.5e-06 28.2 9.9 0.18 11.6 0.2 5.3 1 1 2 5 5 5 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CEP16639.1 - 7.2e-05 22.5 15.6 0.2 11.5 2.1 5.9 7 1 1 8 8 8 3 KH domain PhoPQ_related PF10142.9 CEP16639.1 - 0.00012 20.9 0.2 0.0052 15.5 0.0 2.5 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein YbbR PF07949.12 CEP16639.1 - 0.00098 19.4 9.7 11 6.5 0.5 5.7 5 0 0 5 5 5 2 YbbR-like protein Neur_chan_memb PF02932.16 CEP16639.1 - 8.6 6.3 6.3 21 5.0 6.3 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Integrase_H2C2 PF17921.1 CEP16640.1 - 4.3e-08 33.1 0.9 8.1e-08 32.3 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP16640.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger PAPS_reduct PF01507.19 CEP16641.1 - 4.1e-29 101.8 0.0 9.8e-21 74.6 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Lipase_GDSL_2 PF13472.6 CEP16641.1 - 0.00032 21.1 0.0 0.001 19.5 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEP16641.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase zf-RING_2 PF13639.6 CEP16642.1 - 1.1e-11 44.9 7.2 2.2e-11 43.9 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP16642.1 - 1.1e-09 38.0 7.5 2.2e-09 37.0 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP16642.1 - 1.1e-08 34.8 5.8 2e-08 33.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP16642.1 - 1.5e-06 28.1 1.1 1.5e-06 28.1 1.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP16642.1 - 1.8e-06 27.8 4.9 3.2e-06 27.0 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CEP16642.1 - 2.5e-06 27.2 8.4 4.8e-06 26.3 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP16642.1 - 9.6e-06 25.8 4.0 2.8e-05 24.3 4.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEP16642.1 - 9.2e-05 22.1 2.9 9.2e-05 22.1 2.9 1.8 2 0 0 2 2 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 CEP16642.1 - 0.00089 19.1 7.6 0.0032 17.3 7.7 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CEP16642.1 - 0.0074 16.4 7.1 0.017 15.2 7.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CEP16642.1 - 0.045 13.8 4.9 0.1 12.7 4.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 CEP16642.1 - 0.067 13.3 2.3 0.21 11.7 2.3 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF2808 PF10989.8 CEP16642.1 - 0.083 12.9 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) zf-RING_10 PF16685.5 CEP16642.1 - 0.17 12.1 8.3 0.092 12.9 5.9 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CEP16642.1 - 1.2 8.9 12.0 3.1 7.7 12.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CEP16643.1 - 7.2e-12 45.5 7.6 1.2e-11 44.7 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP16643.1 - 1.8e-10 40.4 0.7 1.8e-10 40.4 0.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CEP16643.1 - 2e-08 33.9 7.1 3.2e-08 33.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 CEP16643.1 - 1.7e-07 31.2 0.1 3.3e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 CEP16643.1 - 2.1e-06 27.5 5.7 3.7e-06 26.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP16643.1 - 0.00012 22.3 7.9 0.00041 20.6 7.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEP16643.1 - 0.00014 21.8 1.4 0.00014 21.8 1.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP16643.1 - 0.0053 16.7 5.9 0.0087 16.0 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CEP16643.1 - 0.0059 16.6 2.6 0.011 15.8 2.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ly49 PF08391.10 CEP16643.1 - 0.025 15.0 0.2 0.059 13.7 0.2 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region zf-C3HC4_3 PF13920.6 CEP16643.1 - 0.037 13.9 6.7 0.061 13.2 6.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CEP16643.1 - 0.31 10.7 5.3 0.61 9.7 5.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CEP16643.1 - 0.34 10.8 8.6 0.64 9.9 8.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CEP16643.1 - 0.76 9.9 6.8 2.2 8.4 6.8 1.8 1 1 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CEP16643.1 - 0.9 9.5 6.8 2.4 8.2 6.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 CEP16643.1 - 2.8 8.2 6.2 30 4.9 6.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RecO_N_2 PF13114.6 CEP16645.1 - 0.00057 19.5 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 RecO N terminal TRIF-NTD PF17798.1 CEP16645.1 - 0.074 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 TRIF N-terminal domain FAP PF07174.11 CEP16645.1 - 0.37 10.2 14.2 0.42 10.0 14.2 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ADH_N PF08240.12 CEP16649.1 - 5.1e-24 84.2 4.1 1.1e-23 83.2 4.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP16649.1 - 4.3e-19 68.8 0.1 1e-18 67.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP16649.1 - 0.08 14.0 0.0 0.37 11.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEP16649.1 - 0.13 11.6 0.1 0.42 9.9 0.1 1.9 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thump_like PF18096.1 CEP16651.1 - 0.028 14.3 2.3 3.1 7.8 0.2 2.4 1 1 1 2 2 2 0 THUMP domain-like HrpB_C PF08482.10 CEP16651.1 - 0.042 14.3 0.6 0.056 13.8 0.6 1.1 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal DUF5408 PF17402.2 CEP16651.1 - 0.064 13.1 0.1 32 4.5 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5408) Scs3p PF10261.9 CEP16652.1 - 3.2e-52 177.5 19.0 8.8e-46 156.4 5.6 2.0 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3270 PF11674.8 CEP16652.1 - 0.047 13.9 0.6 0.047 13.9 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) UCH PF00443.29 CEP16653.1 - 6.3e-27 94.7 0.4 2.1e-26 93.0 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CEP16653.1 - 3.4e-26 91.4 18.2 1.5e-19 70.1 2.7 3.5 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CEP16653.1 - 1.6e-25 88.6 2.5 4.3e-23 80.9 0.3 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger UBA PF00627.31 CEP16653.1 - 1.1e-19 69.9 0.1 8.5e-10 38.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 CEP16653.1 - 3.7e-11 43.2 9.1 3.7e-11 43.2 9.1 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase 4HBT_3 PF13622.6 CEP16654.1 - 1.9e-57 195.4 0.1 3.6e-57 194.5 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CEP16654.1 - 6.7e-33 113.4 0.1 5.6e-27 94.2 0.0 3.4 2 1 0 2 2 2 2 Acyl-CoA thioesterase Tau95 PF09734.9 CEP16655.1 - 4.4e-34 118.3 0.8 1e-33 117.1 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CEP16655.1 - 1.6e-28 99.4 0.0 4.7e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Tau95 Triple barrel domain Laminin_II PF06009.12 CEP16655.1 - 0.00099 19.1 0.7 0.0029 17.6 0.7 1.7 1 0 0 1 1 1 1 Laminin Domain II GldM_N PF12081.8 CEP16655.1 - 0.049 13.7 4.9 0.14 12.2 4.9 1.7 1 0 0 1 1 1 0 GldM N-terminal domain SNARE_assoc PF09335.11 CEP16656.1 - 2.2e-20 73.3 4.6 4.8e-20 72.2 4.6 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein cwf18 PF08315.12 CEP16657.1 - 1.8e-20 73.9 17.1 1.8e-20 73.9 17.1 2.0 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor LapD_MoxY_N PF16448.5 CEP16657.1 - 0.081 12.8 0.4 0.4 10.6 0.1 2.0 1 1 1 2 2 2 0 LapD/MoxY periplasmic domain CAS_CSE1 PF03378.15 CEP16657.1 - 0.095 11.2 0.3 0.1 11.1 0.3 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus PAS PF00989.25 CEP16659.1 - 3e-15 56.2 0.3 5.1e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 CEP16659.1 - 9.1e-11 41.9 0.1 2.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 CEP16659.1 - 2.3e-10 40.6 0.1 1.4e-09 38.1 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 CEP16659.1 - 2.3e-09 37.5 0.0 0.0018 18.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CEP16659.1 - 1.1e-08 35.2 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_2 PF08446.11 CEP16659.1 - 0.0021 18.7 0.0 1.5 9.5 0.0 2.2 2 0 0 2 2 2 2 PAS fold Pyocin_S PF06958.12 CEP16660.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 S-type Pyocin NDC10_II PF16787.5 CEP16662.1 - 0.011 14.8 0.1 1.1 8.2 0.0 2.7 2 1 1 3 3 3 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF3301 PF11743.8 CEP16662.1 - 0.014 15.0 0.1 0.051 13.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3301) SURF4 PF02077.15 CEP16663.1 - 6.9e-94 314.4 8.8 7.9e-94 314.2 8.8 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 CEP16663.1 - 4.5 7.2 7.3 13 5.8 0.3 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DoxX PF07681.12 CEP16663.1 - 7.7 7.2 18.5 0.15 12.7 4.1 3.3 2 1 1 3 3 3 0 DoxX Aldose_epim PF01263.20 CEP16664.1 - 2.3e-44 151.9 0.4 2.5e-44 151.8 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4554 PF15091.6 CEP16664.1 - 0.065 12.1 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Zip PF02535.22 CEP16665.1 - 2.3 7.3 5.1 3.3 6.8 5.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LepA_C PF06421.12 CEP16666.1 - 1e-47 160.7 0.6 4.6e-47 158.6 0.9 2.0 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 CEP16666.1 - 1.5e-41 142.1 0.1 2.4e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CEP16666.1 - 7.3e-22 77.2 0.0 1.7e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEP16666.1 - 6e-07 29.8 0.1 1.5e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEP16666.1 - 9.5e-07 28.7 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CEP16666.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 CEP16666.1 - 0.041 13.9 0.3 0.24 11.4 0.0 2.3 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain AAA_2 PF07724.14 CEP16667.1 - 1.6e-53 181.3 4.0 2.9e-52 177.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CEP16667.1 - 7.3e-36 122.3 2.3 7.3e-36 122.3 2.3 2.8 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CEP16667.1 - 4.7e-24 84.2 1.6 8.3e-24 83.5 0.1 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CEP16667.1 - 3.7e-23 82.4 1.1 4.7e-12 46.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEP16667.1 - 4.1e-16 59.2 0.1 1.8e-10 40.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CEP16667.1 - 7.1e-10 38.8 0.3 3.6e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 CEP16667.1 - 1.6e-09 38.4 0.1 0.0064 16.9 0.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CEP16667.1 - 1.1e-07 32.2 5.0 0.038 14.3 0.0 4.6 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CEP16667.1 - 1.4e-06 28.1 0.0 0.021 14.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEP16667.1 - 1.8e-06 27.5 0.2 0.046 13.1 0.0 3.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CEP16667.1 - 1.9e-06 27.4 0.0 0.0056 16.1 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 CEP16667.1 - 4.7e-06 26.2 0.0 0.028 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 CEP16667.1 - 4.5e-05 23.5 1.0 0.44 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 CEP16667.1 - 7.4e-05 22.5 3.2 0.76 9.5 0.0 4.4 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CEP16667.1 - 0.00011 22.0 0.0 0.056 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP16667.1 - 0.00014 22.4 0.0 0.49 10.9 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CEP16667.1 - 0.00015 22.1 0.0 0.86 10.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase Roc PF08477.13 CEP16667.1 - 0.00034 20.8 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CEP16667.1 - 0.00061 19.7 0.2 0.2 11.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 CEP16667.1 - 0.00062 19.8 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 CEP16667.1 - 0.0024 17.7 0.1 4.1 7.2 0.0 3.8 4 0 0 4 4 4 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 CEP16667.1 - 0.0041 17.1 0.0 5.9 6.8 0.0 3.0 2 0 0 2 2 2 0 RsgA GTPase Bac_DnaA PF00308.18 CEP16667.1 - 0.0079 16.1 0.6 2.7 7.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein ABC_tran PF00005.27 CEP16667.1 - 0.016 15.7 5.3 0.21 12.1 0.0 3.6 3 1 0 3 3 2 0 ABC transporter T3SS_needle_E PF08988.10 CEP16667.1 - 0.028 14.6 2.0 5.6 7.2 0.0 3.2 3 0 0 3 3 2 0 Type III secretion system, cytoplasmic E component of needle SRP54 PF00448.22 CEP16667.1 - 0.032 13.9 0.3 3.9 7.0 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 CEP16667.1 - 0.054 13.3 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CEP16667.1 - 0.057 13.2 0.0 3.7 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CEP16667.1 - 0.065 13.4 0.0 22 5.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CEP16667.1 - 0.17 12.1 2.3 22 5.2 0.0 3.8 4 1 0 4 4 3 0 AAA domain Fez1 PF06818.15 CEP16667.1 - 0.21 12.0 13.2 0.51 10.8 13.2 1.6 1 0 0 1 1 1 0 Fez1 HAUS2 PF15003.6 CEP16667.1 - 0.29 10.8 5.4 0.32 10.7 3.8 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 AAA_30 PF13604.6 CEP16667.1 - 0.78 9.4 6.9 3.4 7.4 0.4 3.8 3 2 0 3 3 3 0 AAA domain DUF1640 PF07798.11 CEP16667.1 - 0.89 9.6 9.6 2.1 8.4 9.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prefoldin PF02996.17 CEP16667.1 - 1.6 8.6 8.8 0.6 10.0 0.5 3.5 3 1 1 4 4 4 0 Prefoldin subunit Atg14 PF10186.9 CEP16667.1 - 5.6 6.0 10.9 9.6 5.2 10.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UCH PF00443.29 CEP16668.1 - 5.8e-43 147.2 1.6 8.3e-43 146.7 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP16668.1 - 1.1e-23 84.4 4.3 1.6e-23 83.8 4.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CEP16668.1 - 0.055 12.9 11.6 0.022 14.3 5.1 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Med25 PF11232.8 CEP16668.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Folliculin PF11704.8 CEP16668.1 - 1.5 8.7 4.0 4.1 7.3 0.5 2.7 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport eIF3g PF12353.8 CEP16669.1 - 4.2e-38 130.6 1.4 8.1e-38 129.6 1.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CEP16669.1 - 8.9e-18 63.9 0.1 2.6e-17 62.4 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NSP11 PF06471.12 CEP16669.1 - 0.0067 15.0 0.0 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 NSP11 RRM_5 PF13893.6 CEP16669.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 CEP16669.1 - 0.027 14.8 0.1 0.055 13.8 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 CEP16669.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif SPOR PF05036.13 CEP16669.1 - 0.11 12.9 1.8 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Sporulation related domain TIG PF01833.24 CEP16670.1 - 1.1e-10 41.4 0.1 3.1e-09 36.8 0.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 CEP16670.1 - 4e-10 40.1 0.8 5.9e-09 36.4 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP16670.1 - 3.4e-09 37.0 0.1 4.5e-07 30.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CEP16670.1 - 4.5e-07 30.0 0.2 0.00053 20.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CEP16670.1 - 5.5e-06 26.6 0.1 0.0003 21.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP16670.1 - 0.00082 19.7 0.1 1.5 9.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat DcuA_DcuB PF03605.14 CEP16670.1 - 0.29 10.0 4.2 4 6.2 0.3 2.2 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Pkinase PF00069.25 CEP16671.1 - 1.5e-67 227.8 0.0 2.5e-67 227.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Asp_protease PF09668.10 CEP16671.1 - 1.2e-50 170.4 0.0 2.1e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Pkinase_Tyr PF07714.17 CEP16671.1 - 1.5e-49 168.6 0.0 3.2e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase gag-asp_proteas PF13975.6 CEP16671.1 - 9.2e-19 67.8 0.0 3.7e-18 65.9 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 CEP16671.1 - 8.9e-11 41.4 0.6 1.8e-10 40.4 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 CEP16671.1 - 3.4e-09 37.2 0.0 1.4e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Pkinase_fungal PF17667.1 CEP16671.1 - 2.6e-05 23.2 0.0 2.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase RVP PF00077.20 CEP16671.1 - 8.4e-05 22.8 0.0 0.00035 20.8 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease XPC-binding PF09280.11 CEP16671.1 - 0.0046 16.7 0.0 0.0046 16.7 0.0 2.6 3 0 0 3 3 3 1 XPC-binding domain Ubiquitin_5 PF18037.1 CEP16671.1 - 0.0066 16.8 0.8 0.031 14.6 0.1 2.4 3 0 0 3 3 2 1 Ubiquitin-like domain Abi_2 PF07751.11 CEP16671.1 - 0.014 15.7 0.9 0.58 10.4 0.0 3.0 3 0 0 3 3 2 0 Abi-like protein Kdo PF06293.14 CEP16671.1 - 0.016 14.6 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEP16671.1 - 0.081 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RVP_2 PF08284.11 CEP16671.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-C2H2 PF00096.26 CEP16672.1 - 4.3e-11 42.6 24.8 5e-05 23.5 0.2 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP16672.1 - 3.2e-06 27.3 20.5 0.00015 22.0 1.1 5.4 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP16672.1 - 7.7e-06 26.3 20.3 0.071 14.0 0.2 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP16672.1 - 2.5e-05 24.2 4.4 0.57 10.2 0.0 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP16672.1 - 0.0035 17.6 9.0 1.1 9.7 4.4 3.2 2 1 1 3 3 3 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP16672.1 - 0.0045 17.6 0.1 0.0045 17.6 0.1 4.9 2 1 3 5 5 5 1 FOXP coiled-coil domain zf_ZIC PF18366.1 CEP16672.1 - 0.0094 16.0 0.1 0.0094 16.0 0.1 3.7 4 0 0 4 4 4 1 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 CEP16672.1 - 4.1 7.5 10.3 1.7 8.7 1.9 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 TFIIA PF03153.13 CEP16672.1 - 4.5 7.2 31.5 15 5.5 31.5 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0524 PF15823.5 CEP16672.1 - 8.8 5.6 13.4 0.095 12.1 0.2 3.1 2 1 1 3 3 3 0 UPF0524 of C3orf70 Maf PF02545.14 CEP16673.1 - 6.7e-50 169.2 0.0 7.6e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MWFE PF15879.5 CEP16674.1 - 3.4e-24 84.8 0.1 4.3e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit zf-RVT PF13966.6 CEP16676.1 - 3.5e-07 30.9 0.2 8.3e-07 29.6 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phage_integrase PF00589.22 CEP16677.1 - 0.00064 19.6 1.1 0.00087 19.1 1.1 1.3 1 0 0 1 1 1 1 Phage integrase family GIT_SHD PF08518.11 CEP16678.1 - 0.047 13.3 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT PIF1 PF05970.14 CEP16679.1 - 9.8e-14 51.3 0.9 2.4e-07 30.2 0.1 2.4 1 1 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.14 CEP16679.1 - 0.0011 17.0 0.0 0.0041 15.1 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.6 CEP16679.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP16679.1 - 0.0035 17.1 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 CEP16679.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 CEP16679.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CEP16679.1 - 0.011 16.1 0.0 0.064 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CEP16679.1 - 0.013 16.0 0.1 0.027 15.0 0.1 1.7 1 1 0 1 1 1 0 ABC transporter UvrD_C_2 PF13538.6 CEP16679.1 - 0.013 15.3 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CEP16679.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEP16679.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RhoGEF PF00621.20 CEP16682.1 - 2.4e-38 132.2 4.5 5.9e-38 130.9 3.1 2.0 2 0 0 2 2 2 1 RhoGEF domain Rsd_AlgQ PF04353.13 CEP16682.1 - 0.036 14.0 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Arrestin_C PF02752.22 CEP16683.1 - 4.7e-13 49.8 1.2 2.2e-06 28.2 0.1 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 CEP16683.1 - 0.0024 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 SpoOM protein Arrestin_N PF00339.29 CEP16683.1 - 0.0027 17.8 0.0 2.5 8.2 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP16683.1 - 0.047 13.4 0.3 0.21 11.3 0.1 2.2 2 1 0 2 2 2 0 Arrestin_N terminal like TIG PF01833.24 CEP16684.1 - 1.1e-10 41.5 1.1 3.5e-10 39.8 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain MCU PF04678.13 CEP16684.1 - 1.6 8.8 5.7 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DDE_3 PF13358.6 CEP16685.1 - 0.031 14.0 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 0 DDE superfamily endonuclease p450 PF00067.22 CEP16686.1 - 8.4e-96 321.5 0.0 1.6e-95 320.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 CEP16686.1 - 1.2e-34 119.8 0.0 2.5e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP16686.1 - 8.8e-25 87.6 0.7 1.9e-24 86.5 0.7 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CEP16686.1 - 2.7e-18 66.6 0.0 8.4e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEP16686.1 - 0.016 15.3 0.0 8.5 6.5 0.0 2.6 1 1 0 2 2 2 0 Ferric reductase NAD binding domain DUF2508 PF10704.9 CEP16686.1 - 2.3 8.4 5.6 5.6 7.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) FlaC_arch PF05377.11 CEP16687.1 - 0.033 14.6 4.8 0.033 14.6 4.8 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4226 PF10774.9 CEP16687.1 - 0.039 14.2 5.3 0.061 13.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Flu_NS2 PF00601.19 CEP16687.1 - 0.081 13.2 3.7 0.089 13.1 2.3 1.7 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) CHDCT2 PF08074.11 CEP16687.1 - 0.2 11.8 7.5 0.23 11.6 7.5 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain LPP20 PF02169.16 CEP16687.1 - 0.72 10.2 4.5 0.36 11.2 2.0 1.8 1 1 1 2 2 2 0 LPP20 lipoprotein Fib_alpha PF08702.10 CEP16687.1 - 1.1 9.5 12.9 1.4 9.1 12.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 CEP16687.1 - 3.5 6.6 17.4 6.7 5.7 17.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Med9 PF07544.13 CEP16687.1 - 3.6 7.7 19.0 3.7 7.7 8.1 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Lge1 PF11488.8 CEP16687.1 - 6.9 6.9 19.6 11 6.2 18.2 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2203 PF09969.9 CEP16687.1 - 8.5 7.1 11.6 1.5e+02 3.1 11.6 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 CEP16687.1 - 8.9 6.1 16.1 0.29 10.9 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4404 PF14357.6 CEP16687.1 - 9.3 7.0 19.5 1.7 9.3 11.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) COPI_assoc PF08507.10 CEP16688.1 - 7e-20 71.4 10.3 9.1e-20 71.0 10.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4386 PF14329.6 CEP16688.1 - 0.026 14.4 2.7 0.026 14.4 2.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4386) DUF2678 PF10856.8 CEP16688.1 - 5.1 7.1 11.1 0.46 10.4 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) AtpR PF12966.7 CEP16688.1 - 5.3 7.6 12.1 2.5 8.6 2.0 2.7 1 1 2 3 3 3 0 N-ATPase, AtpR subunit PEX11 PF05648.14 CEP16689.1 - 1.2e-15 57.7 0.4 2.6e-14 53.2 0.2 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) EMP70 PF02990.16 CEP16690.1 - 7.4e-123 411.0 10.1 9.3e-123 410.6 10.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 MARVEL PF01284.23 CEP16691.1 - 2.3e-08 34.2 8.9 3.6e-08 33.5 8.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain Phage_Gp23 PF10669.9 CEP16691.1 - 0.0023 18.2 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) O-antigen_lig PF13425.6 CEP16691.1 - 0.035 12.9 1.6 1.2 7.9 0.0 2.4 2 1 0 2 2 2 0 O-antigen ligase like membrane protein 2TM PF13239.6 CEP16691.1 - 0.14 12.5 4.1 0.45 10.8 4.1 2.0 1 1 0 1 1 1 0 2TM domain Ran_BP1 PF00638.18 CEP16693.1 - 3.7e-48 162.8 1.6 6.2e-48 162.1 1.6 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CEP16693.1 - 1.7e-06 27.9 0.4 7.3e-06 25.9 0.4 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 CEP16693.1 - 0.0038 16.9 1.0 0.0051 16.5 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WD40 PF00400.32 CEP16695.1 - 2.6e-12 47.0 0.5 6.2e-06 26.9 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16695.1 - 9.1e-08 32.3 0.0 0.05 13.9 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CEP16695.1 - 0.0057 16.6 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat MBOAT_2 PF13813.6 CEP16697.1 - 1.1e-14 54.4 3.6 3e-14 53.0 3.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MSP1a PF11670.8 CEP16697.1 - 0.06 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) LEA_2 PF03168.13 CEP16698.1 - 0.0017 18.9 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DOMON PF03351.17 CEP16698.1 - 0.063 13.5 0.5 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 DOMON domain FtsX PF02687.21 CEP16698.1 - 0.56 10.7 7.2 1.1 9.8 7.2 1.4 1 0 0 1 1 1 0 FtsX-like permease family ETC_C1_NDUFA5 PF04716.14 CEP16699.1 - 2.1e-28 97.9 0.6 2.1e-28 97.9 0.6 1.6 2 0 0 2 2 2 1 ETC complex I subunit conserved region Topoisom_bac PF01131.20 CEP16700.1 - 2.7e-110 369.2 0.0 6.5e-110 368.0 0.0 1.6 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 CEP16700.1 - 4.6e-10 39.7 0.0 1.2e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Toprim domain EF-hand_6 PF13405.6 CEP16700.1 - 6.5e-07 28.8 3.4 6.1e-05 22.6 0.2 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CEP16700.1 - 7.1e-07 29.6 1.9 2.9e-06 27.6 1.9 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CEP16700.1 - 0.00019 20.7 3.7 0.053 13.1 0.2 3.2 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CEP16700.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CEP16700.1 - 0.36 10.4 1.1 11 5.7 0.1 2.6 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.16 CEP16701.1 - 2.7e-36 125.2 29.9 2.9e-36 125.1 28.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP16701.1 - 4.8e-12 45.5 23.8 2.4e-11 43.2 23.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1772 PF08592.11 CEP16701.1 - 0.63 10.3 13.2 7.8 6.8 0.2 3.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) MFS_1 PF07690.16 CEP16702.1 - 1.2e-34 119.8 31.5 1.2e-34 119.8 31.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 CEP16702.1 - 5.1 7.4 13.5 1.7 8.9 3.9 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) Methyltr_RsmB-F PF01189.17 CEP16704.1 - 7.7e-77 257.5 0.1 6.2e-76 254.5 0.0 2.3 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CEP16704.1 - 2.9e-08 34.1 2.2 3.9e-08 33.7 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_31 PF13847.6 CEP16704.1 - 0.0051 16.6 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CEP16704.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase BUD22 PF09073.10 CEP16704.1 - 3.6 6.8 49.8 0.035 13.5 36.1 2.3 2 0 0 2 2 2 0 BUD22 DHFR_1 PF00186.19 CEP16705.1 - 9.2e-39 132.7 0.0 3e-38 131.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase CoaE PF01121.20 CEP16706.1 - 1.9e-49 167.8 0.4 2.4e-49 167.4 0.4 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CEP16706.1 - 0.015 15.8 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ufd2P_core PF10408.9 CEP16707.1 - 1.8e-222 740.4 11.7 2.7e-222 739.8 11.7 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CEP16707.1 - 9.5e-23 80.2 0.2 4.1e-22 78.1 0.2 2.2 1 0 0 1 1 1 1 U-box domain DUF1079 PF06435.11 CEP16707.1 - 0.11 12.8 0.6 1.9 8.8 0.1 3.1 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) MRP-L27 PF09809.9 CEP16708.1 - 8.8e-20 70.6 0.2 9.3e-20 70.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cullin_binding PF03556.15 CEP16709.1 - 1.9e-31 109.0 0.7 3.8e-31 108.0 0.7 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CEP16709.1 - 2.1e-07 30.6 0.1 4.2e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain AIM24 PF01987.17 CEP16710.1 - 3.2e-40 138.1 0.0 4.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Nipped-B_C PF12830.7 CEP16711.1 - 2e-46 158.3 0.9 9.6e-44 149.6 0.2 3.0 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus IPK PF03770.16 CEP16711.1 - 5.9e-31 107.9 0.1 1.5e-30 106.5 0.1 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase Cohesin_HEAT PF12765.7 CEP16711.1 - 1e-05 25.7 4.0 2.4e-05 24.5 1.1 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CEP16711.1 - 4.9e-05 23.2 3.5 1.9 9.0 0.1 5.6 5 0 0 5 5 5 2 HEAT repeat Mucin PF01456.17 CEP16711.1 - 0.0023 17.9 12.2 0.038 14.0 12.5 2.4 2 0 0 2 2 2 1 Mucin-like glycoprotein Cnd1 PF12717.7 CEP16711.1 - 0.0074 16.3 2.8 0.041 13.9 0.8 3.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP16711.1 - 0.0093 16.3 1.5 0.066 13.6 0.5 2.8 2 0 0 2 2 2 1 HEAT repeats IMUP PF15761.5 CEP16711.1 - 0.073 13.8 4.0 0.22 12.2 4.0 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein CH PF00307.31 CEP16712.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2722 PF10846.8 CEP16712.1 - 0.0012 17.9 4.0 0.0017 17.4 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CEP16712.1 - 0.0034 18.2 7.2 0.0034 18.2 7.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CEP16712.1 - 0.17 11.5 12.9 0.35 10.5 12.9 1.4 1 0 0 1 1 1 0 Spt20 family DUF2967 PF11179.8 CEP16712.1 - 2.3 6.2 8.9 4.1 5.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Lipase_GDSL PF00657.22 CEP16713.1 - 6.7e-14 52.3 0.3 9.8e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP16713.1 - 1.9e-08 34.9 0.0 1.4e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_S8 PF00082.22 CEP16714.1 - 2.7e-28 99.1 11.8 6.9e-28 97.8 11.8 1.7 1 1 0 1 1 1 1 Subtilase family zf-CSL PF05207.13 CEP16714.1 - 2.4e-20 72.0 1.7 4.2e-20 71.2 1.7 1.4 1 0 0 1 1 1 1 CSL zinc finger XRCC4 PF06632.12 CEP16714.1 - 0.78 8.5 8.0 1.3 7.9 8.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spb1_C PF07780.12 CEP16715.1 - 1.5e-75 253.5 27.4 1.5e-75 253.5 27.4 4.3 2 1 2 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 CEP16715.1 - 8.8e-57 192.1 0.1 2.3e-56 190.7 0.1 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CEP16715.1 - 2.3e-45 154.3 16.8 2.3e-45 154.3 16.8 6.1 2 1 2 5 5 5 1 Domain of unknown function (DUF3381) Adap_comp_sub PF00928.21 CEP16718.1 - 4.4e-86 288.5 0.1 5.5e-86 288.2 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CEP16718.1 - 0.0051 16.7 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain fn3_6 PF17766.1 CEP16718.1 - 0.087 13.0 0.5 0.25 11.5 0.1 2.1 2 0 0 2 2 2 0 Fibronectin type-III domain PIG-S PF10510.9 CEP16719.1 - 4.9e-122 408.4 13.8 1.1e-116 390.8 5.4 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HhH-GPD PF00730.25 CEP16719.1 - 1.3e-23 83.5 0.0 3.4e-23 82.2 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CEP16719.1 - 7.6e-15 54.8 0.0 1.8e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 CEP16719.1 - 1.5e-06 27.8 0.0 4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CEP16719.1 - 0.022 15.1 5.6 0.039 14.3 5.6 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III zf-RVT PF13966.6 CEP16720.1 - 0.0004 21.0 1.0 0.00076 20.1 1.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP16721.1 - 2.4e-24 86.1 0.0 6.1e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 CEP16722.1 - 0.017 15.2 0.9 0.017 15.2 0.9 2.0 2 0 0 2 2 2 0 Zinc knuckle F-box-like PF12937.7 CEP16724.1 - 2.6e-05 24.0 0.3 5.9e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP16724.1 - 0.00019 21.2 0.1 0.00068 19.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain Regnase_1_C PF18561.1 CEP16724.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain PIP5K PF01504.18 CEP16725.1 - 9.5e-39 133.3 0.7 2.9e-34 118.5 1.5 2.7 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CEP16725.1 - 1.1e-26 93.6 0.1 1.8e-26 92.9 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CEP16725.1 - 9e-14 51.4 11.5 2.6e-13 49.9 11.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger PRIMA1 PF16101.5 CEP16725.1 - 4.4 7.4 10.5 15 5.7 10.5 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_34 PF11312.8 CEP16726.1 - 0.033 13.4 0.5 0.051 12.8 0.5 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase RVT_1 PF00078.27 CEP16727.1 - 1.6e-11 44.1 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4366 PF14283.6 CEP16728.1 - 0.029 14.4 0.8 0.041 13.9 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CEP16728.1 - 0.096 11.4 4.0 0.11 11.2 4.0 1.0 1 0 0 1 1 1 0 Presenilin zf-CCHC_2 PF13696.6 CEP16729.1 - 0.0021 17.8 16.8 0.016 15.0 1.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CEP16729.1 - 0.0026 17.7 12.5 0.025 14.6 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP16729.1 - 0.027 14.2 4.1 0.027 14.2 4.1 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CEP16732.1 - 0.0011 18.8 3.1 0.019 14.8 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP16732.1 - 0.17 11.6 6.0 1.2 8.9 0.4 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger DDE_3 PF13358.6 CEP16735.1 - 2.7e-13 49.9 0.1 3.8e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease VirB8 PF04335.13 CEP16736.1 - 0.076 12.8 0.4 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 VirB8 protein RVT_1 PF00078.27 CEP16737.1 - 2e-05 24.2 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavodoxin_NdrI PF07972.11 CEP16738.1 - 0.079 13.1 0.7 2.8 8.1 0.1 2.4 1 1 0 2 2 2 0 NrdI Flavodoxin like HTH_29 PF13551.6 CEP16741.1 - 0.0028 17.6 0.0 0.0036 17.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 CEP16742.1 - 3.8e-21 75.4 0.0 3.2e-19 69.1 0.0 2.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Tagatose_6_P_K PF08013.11 CEP16742.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Retrotran_gag_2 PF14223.6 CEP16743.1 - 0.029 14.0 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GATA PF00320.27 CEP16743.1 - 0.31 10.7 2.5 0.8 9.4 2.5 1.7 1 0 0 1 1 1 0 GATA zinc finger COesterase PF00135.28 CEP16744.1 - 4.2e-76 256.9 0.0 2.8e-50 171.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Iso_dh PF00180.20 CEP16745.1 - 2.5e-97 326.2 0.0 8.3e-97 324.4 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Isochorismatase PF00857.20 CEP16746.1 - 5.8e-36 124.3 0.0 6.3e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NYN PF01936.18 CEP16746.1 - 0.006 17.1 0.0 0.0092 16.5 0.0 1.2 1 0 0 1 1 1 1 NYN domain CIAPIN1 PF05093.13 CEP16747.1 - 1.8e-25 89.4 0.9 2.7e-25 88.8 0.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis G-gamma PF00631.22 CEP16748.1 - 1.7e-15 56.8 0.1 2.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 GGL domain ERCC4 PF02732.15 CEP16749.1 - 9.9e-24 84.3 0.1 3.4e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain tRNA_synthFbeta PF17759.1 CEP16749.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Arm PF00514.23 CEP16750.1 - 1.8e-83 272.3 14.8 7.3e-14 51.3 0.2 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CEP16750.1 - 2.9e-21 74.8 0.0 5.8e-20 70.6 0.1 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CEP16750.1 - 2.1e-20 72.8 2.9 0.00034 21.0 0.0 7.0 6 2 1 7 7 7 5 HEAT-like repeat HEAT PF02985.22 CEP16750.1 - 2.1e-18 64.8 3.2 0.0037 17.4 0.0 8.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 CEP16750.1 - 1.9e-16 60.2 0.2 2.1e-05 24.8 0.0 5.4 2 1 5 7 7 7 5 HEAT repeats Arm_2 PF04826.13 CEP16750.1 - 4.8e-07 29.5 0.0 0.18 11.3 0.0 4.2 2 1 2 4 4 4 1 Armadillo-like Adaptin_N PF01602.20 CEP16750.1 - 6.8e-06 24.9 0.0 0.00087 18.0 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 CEP16750.1 - 1.8e-05 24.8 0.0 0.86 9.7 0.0 4.5 3 3 3 6 6 6 2 V-ATPase subunit H RICTOR_V PF14668.6 CEP16750.1 - 0.0034 17.6 4.3 2.2 8.6 0.0 3.9 2 2 2 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 CEP16750.1 - 0.0041 17.2 0.0 0.42 10.6 0.0 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 CEP16750.1 - 0.042 13.9 0.5 0.67 10.0 0.0 2.9 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 CEP16750.1 - 0.088 13.5 0.2 11 7.0 0.0 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 CEP16750.1 - 0.1 11.1 0.0 0.22 10.0 0.0 1.6 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit PsbY PF06298.11 CEP16750.1 - 0.12 12.2 2.3 1.6 8.7 0.0 3.6 4 0 0 4 4 4 0 Photosystem II protein Y (PsbY) Complex1_LYR_2 PF13233.6 CEP16751.1 - 7.2e-07 29.9 0.8 2.6e-06 28.1 0.8 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CEP16751.1 - 9.6e-05 22.4 2.2 0.015 15.3 0.1 3.0 1 1 1 2 2 2 2 Complex 1 protein (LYR family) DUF5582 PF17819.1 CEP16751.1 - 0.0021 18.5 0.5 0.0027 18.2 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DDHD PF02862.17 CEP16752.1 - 2.7e-48 165.1 0.1 1.9e-46 159.1 0.0 2.6 2 0 0 2 2 2 1 DDHD domain WWE PF02825.20 CEP16752.1 - 4.1e-05 24.1 0.1 0.11 13.1 0.0 3.2 2 0 0 2 2 2 2 WWE domain CBFB_NFYA PF02045.15 CEP16753.1 - 4.9e-30 103.9 5.9 8.3e-30 103.2 5.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Nucleos_tra2_C PF07662.13 CEP16754.1 - 2e-69 233.6 7.3 2e-69 233.6 7.3 2.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CEP16754.1 - 2e-24 86.0 4.5 2e-24 86.0 4.5 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CEP16754.1 - 0.31 11.3 12.5 1.1 9.6 5.2 3.3 2 1 0 2 2 2 0 Nucleoside recognition Sec2p PF06428.11 CEP16755.1 - 6.8e-16 58.0 10.7 6.8e-16 58.0 10.7 3.3 3 0 0 3 3 3 2 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 CEP16755.1 - 0.73 10.3 4.4 2.9 8.4 0.5 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FliD_N PF02465.18 CEP16755.1 - 0.76 10.5 19.2 1.3 9.7 2.4 4.3 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 CEP16755.1 - 3.2 7.8 10.7 1.1 9.3 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NIF PF03031.18 CEP16756.1 - 6e-14 52.1 4.2 1.9e-13 50.5 0.5 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Pkinase PF00069.25 CEP16757.1 - 6.1e-62 209.4 0.0 7.2e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16757.1 - 6.9e-20 71.4 0.0 2.1e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP16757.1 - 7.7e-05 22.1 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CEP16757.1 - 0.00089 19.2 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP16757.1 - 0.042 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GDA1_CD39 PF01150.17 CEP16758.1 - 1.8e-105 353.1 0.0 2.4e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CEP16758.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RT_RNaseH_2 PF17919.1 CEP16760.1 - 3e-32 110.6 0.0 6.3e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP16760.1 - 1.9e-30 105.2 0.0 5e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP16760.1 - 3.2e-22 79.1 0.0 6.9e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CEP16760.1 - 4.2e-16 59.2 0.0 1.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP16760.1 - 3.5e-15 55.8 0.7 9.1e-15 54.5 0.7 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP16760.1 - 0.002 17.9 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_3 PF13456.6 CEP16760.1 - 0.051 13.4 0.1 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like DUF4449 PF14613.6 CEP16761.1 - 0.00099 19.2 2.0 0.00099 19.2 2.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4449) Retrotrans_gag PF03732.17 CEP16761.1 - 0.005 17.1 2.6 0.005 17.1 2.6 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein Cwf_Cwc_15 PF04889.12 CEP16761.1 - 0.89 9.2 16.5 2.4 7.8 16.4 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4449 PF14613.6 CEP16762.1 - 0.0004 20.5 4.4 0.0004 20.5 4.4 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) zf-CCHC PF00098.23 CEP16762.1 - 0.0095 16.0 1.7 0.0095 16.0 1.7 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF1658 PF07871.11 CEP16762.1 - 0.016 15.1 0.7 8.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) GlyL_C PF12524.8 CEP16762.1 - 2.3 8.4 6.8 24 5.2 2.9 2.8 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal zf-CCHC_3 PF13917.6 CEP16762.1 - 5.4 7.1 15.2 0.94 9.5 6.5 3.0 1 1 1 2 2 2 0 Zinc knuckle SDA1 PF05285.12 CEP16763.1 - 0.03 13.7 2.2 0.041 13.3 2.2 1.1 1 0 0 1 1 1 0 SDA1 RVT_1 PF00078.27 CEP16763.1 - 0.073 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP16764.1 - 0.00063 19.3 0.1 0.00086 18.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP16765.1 - 1.4e-17 63.5 0.0 3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP16765.1 - 4.4e-15 55.5 0.5 8.8e-15 54.6 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CEP16765.1 - 1.1e-13 51.4 0.0 1.3e-12 47.9 0.0 2.2 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-C2H2_10 PF16588.5 CEP16769.1 - 0.011 15.5 13.3 0.013 15.2 4.9 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CHC2 PF01807.20 CEP16769.1 - 0.013 15.2 0.7 0.027 14.3 0.7 1.6 1 1 0 1 1 1 0 CHC2 zinc finger zf-CCHC PF00098.23 CEP16769.1 - 0.05 13.7 13.9 0.51 10.5 3.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 CEP16769.1 - 5.3 7.0 18.7 1.1 9.1 6.0 2.5 2 0 0 2 2 2 0 Zinc knuckle TraG-D_C PF12696.7 CEP16770.1 - 0.28 11.2 1.5 0.39 10.7 1.5 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG rve PF00665.26 CEP16771.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain MULE PF10551.9 CEP16772.1 - 3.6e-10 40.1 0.4 1.3e-09 38.3 0.4 2.0 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CEP16772.1 - 1.4e-05 24.2 0.7 1.4e-05 24.2 0.7 1.9 2 0 0 2 2 2 1 Transposase, Mutator family SWIM PF04434.17 CEP16772.1 - 0.0001 21.9 0.2 0.00021 20.9 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.15 CEP16772.1 - 0.00044 20.9 0.4 0.0016 19.1 0.4 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain WRKY PF03106.15 CEP16772.1 - 0.0013 18.9 0.6 0.0041 17.3 0.0 2.1 2 0 0 2 2 2 1 WRKY DNA -binding domain REV PF00424.18 CEP16772.1 - 0.032 14.2 0.4 0.81 9.8 0.2 3.1 2 1 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DDE_Tnp_ISL3 PF01610.17 CEP16772.1 - 0.2 11.3 6.7 0.027 14.2 1.1 2.3 3 1 0 3 3 3 0 Transposase zf-CCHC PF00098.23 CEP16773.1 - 0.0014 18.7 15.5 0.0046 17.0 1.3 2.6 3 0 0 3 3 3 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP16773.1 - 0.012 15.4 4.1 0.012 15.4 4.1 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP16773.1 - 0.036 13.9 17.6 0.75 9.7 2.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP16773.1 - 0.67 9.7 5.1 2.5 7.9 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.6 CEP16776.1 - 0.00012 21.8 0.1 0.00024 20.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF896 PF05979.12 CEP16776.1 - 0.025 14.5 0.1 0.076 12.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) eRF1_2 PF03464.15 CEP16776.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 eRF1 domain 2 CENP-B_N PF04218.13 CEP16778.1 - 0.00024 20.7 0.1 0.003 17.1 0.1 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 CEP16778.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc5 PF03221.16 CEP16778.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CEP16778.1 - 0.12 12.1 0.6 0.98 9.2 0.0 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain zf-CCHC PF00098.23 CEP16779.1 - 5e-05 23.2 2.1 0.0001 22.2 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2057 PF09829.9 CEP16779.1 - 0.011 15.9 0.6 0.016 15.4 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3461 PF11944.8 CEP16779.1 - 0.11 12.6 0.3 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) FTA4 PF13093.6 CEP16780.1 - 0.0014 18.6 0.4 0.0025 17.7 0.4 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TolA_bind_tri PF16331.5 CEP16780.1 - 0.0046 17.0 5.5 0.013 15.5 5.5 1.8 1 0 0 1 1 1 1 TolA binding protein trimerisation Cluap1 PF10234.9 CEP16780.1 - 0.021 14.2 0.2 0.054 12.9 0.2 1.6 1 0 0 1 1 1 0 Clusterin-associated protein-1 FemAB PF02388.16 CEP16780.1 - 0.056 12.3 0.2 0.12 11.3 0.2 1.4 1 0 0 1 1 1 0 FemAB family RICH PF05062.12 CEP16780.1 - 0.26 11.7 2.8 0.38 11.1 0.2 2.4 2 0 0 2 2 2 0 RICH domain SKA1 PF07160.12 CEP16780.1 - 9.4 6.0 10.3 0.068 13.0 1.0 2.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 RVT_1 PF00078.27 CEP16781.1 - 4e-15 55.9 0.1 6.4e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CEP16781.1 - 7.1e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP16782.1 - 5.7e-12 45.9 0.0 8.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP16782.1 - 3.4e-07 30.1 0.5 6.3e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP16782.1 - 0.14 12.0 0.2 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain TSR PF18487.1 CEP16783.1 - 0.00014 22.0 7.0 0.00027 21.1 7.0 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 repeat zf-ISL3 PF14690.6 CEP16783.1 - 0.0078 16.9 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PIF1 PF05970.14 CEP16785.1 - 1.1e-29 103.8 0.1 9e-19 67.9 0.0 2.4 1 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CEP16785.1 - 5.7e-28 98.4 0.0 1.2e-27 97.4 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CEP16785.1 - 1.7e-17 63.7 0.0 2.9e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP16785.1 - 7.3e-08 32.9 0.0 1.8e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP16785.1 - 0.00017 21.4 0.0 0.11 12.2 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CEP16785.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CEP16785.1 - 0.011 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEP16785.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Asp_protease_2 PF13650.6 CEP16786.1 - 1.9e-06 28.4 0.0 4.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CEP16786.1 - 9.7e-05 22.3 10.4 0.00021 21.2 3.0 2.5 1 1 1 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.6 CEP16786.1 - 0.00011 22.7 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease YlbD_coat PF14071.6 CEP16786.1 - 0.01 16.1 1.7 0.034 14.4 1.7 1.8 1 0 0 1 1 1 0 Putative coat protein zf-CCHC_3 PF13917.6 CEP16786.1 - 4.7 7.3 12.7 0.96 9.5 1.7 2.5 1 1 1 2 2 2 0 Zinc knuckle rve PF00665.26 CEP16787.1 - 4.4e-14 52.7 0.0 6.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP16787.1 - 0.029 14.1 0.0 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 Integrase core domain BTG PF07742.12 CEP16787.1 - 0.1 12.5 0.5 0.46 10.3 0.1 2.1 2 1 1 3 3 3 0 BTG family rve PF00665.26 CEP16788.1 - 1.1e-24 86.9 0.0 6.4e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain RVT_1 PF00078.27 CEP16788.1 - 7.1e-23 81.3 0.1 7.1e-23 81.3 0.1 2.8 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP16788.1 - 3.7e-20 72.2 0.3 1.4e-19 70.3 0.1 2.1 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP16788.1 - 9.2e-11 41.7 0.4 7.2e-10 38.8 0.0 2.6 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CEP16788.1 - 3.3e-07 30.8 0.0 7.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP16788.1 - 4.1e-07 30.6 0.0 9.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 CEP16788.1 - 2e-05 24.6 0.1 6.6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CEP16788.1 - 3.5e-05 23.5 0.2 0.46 10.3 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain MLVIN_C PF18697.1 CEP16788.1 - 0.0001 22.4 0.1 0.00023 21.2 0.1 1.6 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP_2 PF08284.11 CEP16788.1 - 0.00081 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease 14-3-3 PF00244.20 CEP16788.1 - 0.0083 15.7 0.0 3.8 6.9 0.0 2.7 2 0 0 2 2 2 2 14-3-3 protein DDE_Tnp_IS240 PF13610.6 CEP16788.1 - 0.0084 16.3 0.4 1.9 8.7 0.1 2.6 2 0 0 2 2 2 1 DDE domain Asp_protease PF09668.10 CEP16788.1 - 0.014 15.2 0.0 0.052 13.3 0.0 2.0 3 0 0 3 3 3 0 Aspartyl protease CelTOS PF18659.1 CEP16788.1 - 0.076 13.5 0.0 28 5.2 0.0 3.0 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites BLACT_WH PF17778.1 CEP16788.1 - 0.12 12.4 4.9 34 4.5 0.1 3.5 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain DUF1829 PF08862.10 CEP16788.1 - 0.13 12.8 0.3 43 4.7 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF1829 DUF272 PF03312.15 CEP16788.1 - 0.16 12.3 0.5 33 4.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF272) Retrotrans_gag PF03732.17 CEP16789.1 - 3.8e-06 27.1 0.1 6.8e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PGM_PMM_II PF02879.16 CEP16791.1 - 0.19 12.4 0.0 0.77 10.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FRD2 PF03197.13 CEP16792.1 - 0.065 13.5 0.1 0.071 13.4 0.1 1.0 1 0 0 1 1 1 0 Bacteriophage FRD2 protein zf-C2H2_6 PF13912.6 CEP16793.1 - 0.073 13.1 0.3 0.073 13.1 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CEP16793.1 - 0.22 12.5 3.6 1.2 10.2 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger VASP_tetra PF08776.11 CEP16797.1 - 0.069 12.7 0.1 8.3 6.1 0.0 2.2 2 0 0 2 2 2 0 VASP tetramerisation domain CUE PF02845.16 CEP16797.1 - 0.072 12.8 1.3 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 CUE domain Chromo PF00385.24 CEP16798.1 - 2.8e-08 33.5 0.2 4.3e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Snf7 PF03357.21 CEP16799.1 - 7.8e-44 149.3 21.6 1.1e-43 148.9 21.6 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 CEP16799.1 - 0.26 11.2 8.5 0.4 10.6 8.5 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Allexi_40kDa PF05549.11 CEP16799.1 - 4.7 6.7 7.9 2.7 7.5 4.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2570 PF10828.8 CEP16799.1 - 5.8 6.8 8.7 0.27 11.0 2.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) RNA_pol_Rpb8 PF03870.15 CEP16800.1 - 6.1e-52 175.5 0.2 6.8e-52 175.4 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CEP16800.1 - 0.042 13.9 0.1 9.4 6.3 0.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G Ribosomal_L1 PF00687.21 CEP16801.1 - 3.2e-39 134.8 4.2 4e-39 134.5 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Homeobox_KN PF05920.11 CEP16801.1 - 0.064 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain BolA PF01722.18 CEP16802.1 - 4e-30 103.9 4.1 7e-30 103.1 4.1 1.4 1 0 0 1 1 1 1 BolA-like protein Sod_Fe_N PF00081.22 CEP16802.1 - 0.059 13.9 3.5 1.5 9.4 3.3 2.4 2 1 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ipi1_N PF12333.8 CEP16803.1 - 4.7e-22 78.5 2.4 1.3e-21 77.0 1.7 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DUF2281 PF10047.9 CEP16803.1 - 0.0013 19.4 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2281) Dopey_N PF04118.14 CEP16803.1 - 0.0032 16.6 0.2 0.0081 15.3 0.2 1.7 1 0 0 1 1 1 1 Dopey, N-terminal ABC_membrane PF00664.23 CEP16804.1 - 3.2e-59 200.8 24.5 5e-38 131.3 6.6 3.4 2 2 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP16804.1 - 2.5e-52 177.0 0.0 1e-31 110.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CEP16804.1 - 3.7e-10 39.6 6.2 0.0031 17.0 2.8 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CEP16804.1 - 2.1e-05 23.8 0.0 0.17 10.9 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 CEP16804.1 - 2.1e-05 25.0 0.2 0.064 13.6 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEP16804.1 - 4.5e-05 23.1 0.5 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CEP16804.1 - 8.2e-05 23.2 2.7 0.046 14.2 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 CEP16804.1 - 0.0001 22.0 0.0 0.19 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CEP16804.1 - 0.00021 21.1 0.1 0.57 9.9 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 CEP16804.1 - 0.00061 20.1 4.0 0.3 11.3 0.5 3.4 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CEP16804.1 - 0.0008 19.5 0.1 0.093 12.8 0.1 2.7 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 CEP16804.1 - 0.001 19.2 1.4 0.1 12.7 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 CEP16804.1 - 0.0012 18.7 0.6 4.3 7.1 0.0 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CEP16804.1 - 0.0023 17.7 0.1 0.55 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CEP16804.1 - 0.0028 17.6 0.2 0.4 10.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP16804.1 - 0.0044 17.1 0.5 0.83 9.8 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 CEP16804.1 - 0.0053 17.0 0.2 36 4.7 0.0 3.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CEP16804.1 - 0.0082 15.4 1.0 0.077 12.2 0.1 2.6 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 CEP16804.1 - 0.017 15.6 0.1 11 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CEP16804.1 - 0.023 14.9 0.2 6.2 7.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CEP16804.1 - 0.04 14.1 4.2 1.2 9.3 0.1 3.5 4 1 0 4 4 2 0 AAA domain Zeta_toxin PF06414.12 CEP16804.1 - 0.046 13.0 0.1 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CEP16804.1 - 0.06 12.7 0.3 11 5.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CEP16804.1 - 0.062 12.8 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CEP16804.1 - 0.063 12.9 1.9 0.7 9.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CEP16804.1 - 0.064 13.2 3.5 3.7 7.4 0.1 3.1 3 0 0 3 3 3 0 NACHT domain AAA PF00004.29 CEP16804.1 - 0.068 13.6 0.2 11 6.5 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) EMC3_TMCO1 PF01956.16 CEP16804.1 - 0.098 12.4 5.9 0.026 14.2 1.6 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AAA_15 PF13175.6 CEP16804.1 - 0.12 12.1 1.2 14 5.3 0.3 2.5 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 CEP16804.1 - 0.13 12.2 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 CEP16804.1 - 0.15 11.5 0.7 13 5.2 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 CEP16804.1 - 0.32 11.0 1.1 66 3.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 CEP16804.1 - 0.69 9.7 2.9 18 5.0 0.0 3.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.17 CEP16804.1 - 9.8 5.9 6.2 25 4.5 0.2 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Alginate_lyase PF05426.12 CEP16805.1 - 3.9e-47 161.1 0.1 8.6e-47 160.0 0.1 1.6 1 0 0 1 1 1 1 Alginate lyase HMG_box PF00505.19 CEP16807.1 - 6.6e-19 68.1 1.0 1.3e-18 67.1 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP16807.1 - 1.9e-08 34.8 0.4 4.5e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain AAA_12 PF13087.6 CEP16808.1 - 1.1e-38 132.9 0.0 2.1e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP16808.1 - 1.3e-25 90.7 2.3 7e-12 45.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CEP16808.1 - 2.2e-10 41.1 0.0 1.9e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CEP16808.1 - 6.2e-09 35.8 0.0 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CEP16808.1 - 0.0041 16.4 0.0 0.079 12.2 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CEP16808.1 - 0.0062 16.0 0.1 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 CEP16808.1 - 0.0072 16.3 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CEP16808.1 - 0.01 15.4 2.0 0.076 12.5 2.0 2.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CEP16808.1 - 0.032 14.5 1.4 5 7.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CEP16808.1 - 0.093 13.3 0.0 1.6 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CEP16808.1 - 0.11 12.2 0.1 1.2 8.9 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase Pyr_redox_2 PF07992.14 CEP16809.1 - 9.7e-66 222.0 0.6 1.4e-65 221.4 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEP16809.1 - 6.5e-31 106.9 0.5 1.3e-30 105.9 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEP16809.1 - 3.1e-18 66.1 5.9 1.1e-16 61.1 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP16809.1 - 1.8e-14 53.7 2.8 9.1e-14 51.4 2.8 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEP16809.1 - 1.4e-06 27.7 0.0 3.3e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CEP16809.1 - 3.9e-06 26.5 0.1 6.4e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP16809.1 - 1.3e-05 24.1 3.0 0.036 12.8 0.5 3.9 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CEP16809.1 - 2.7e-05 23.6 0.8 0.048 13.0 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CEP16809.1 - 0.00043 20.5 4.6 0.00043 20.5 4.6 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CEP16809.1 - 0.0013 17.9 7.4 0.12 11.4 4.0 3.4 3 1 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 CEP16809.1 - 0.0015 17.9 0.0 0.0015 17.9 0.0 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CEP16809.1 - 0.0022 17.2 9.2 0.0054 15.9 3.4 3.4 3 1 1 4 4 4 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CEP16809.1 - 0.0027 17.3 0.8 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 CEP16809.1 - 0.0043 16.9 1.0 0.0079 16.1 0.0 2.0 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 CEP16809.1 - 0.0045 16.3 0.3 0.012 14.9 0.3 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CEP16809.1 - 0.058 13.0 15.0 0.026 14.1 3.3 3.4 3 1 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CEP16809.1 - 0.11 13.0 0.1 4.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CEP16809.1 - 2.5 7.3 5.1 40 3.3 0.1 3.0 2 1 1 3 3 3 0 FAD binding domain zf-Tim10_DDP PF02953.15 CEP16810.1 - 9.2e-21 73.3 0.2 1.8e-20 72.4 0.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CEP16810.1 - 0.021 14.5 1.4 0.025 14.3 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Glyco_transf_20 PF00982.21 CEP16811.1 - 1e-196 654.2 0.0 1.4e-196 653.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP16811.1 - 9.9e-54 181.9 0.0 2.2e-53 180.8 0.0 1.6 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 CEP16811.1 - 3.6e-06 26.9 0.0 1.4e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_trans_1_4 PF13692.6 CEP16811.1 - 0.00069 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Aminotran_4 PF01063.19 CEP16813.1 - 2.3e-18 66.9 0.0 3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV potato_inhibit PF00280.18 CEP16813.1 - 0.0038 17.9 0.3 0.011 16.4 0.1 1.9 2 0 0 2 2 2 1 Potato inhibitor I family Ribosomal_L7Ae PF01248.26 CEP16814.1 - 8.2e-23 80.0 1.6 1.7e-22 79.0 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 CEP16814.1 - 0.034 14.0 0.9 0.062 13.2 0.9 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RasGAP PF00616.19 CEP16815.1 - 1.9e-56 191.1 1.5 4.7e-56 189.8 0.0 2.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEP16815.1 - 1.9e-35 122.0 1.2 1.9e-35 122.0 1.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus Ribosomal_L29 PF00831.23 CEP16815.1 - 0.022 14.7 0.6 2.4 8.2 0.0 3.1 2 0 0 2 2 2 0 Ribosomal L29 protein CTK3 PF12243.8 CEP16815.1 - 0.055 13.5 0.2 1 9.4 0.0 3.1 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 RasGEF_N_2 PF14663.6 CEP16815.1 - 0.076 13.4 1.2 0.38 11.2 1.2 2.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Abhydrolase_3 PF07859.13 CEP16816.1 - 1.5e-19 70.7 0.0 3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PPR_2 PF13041.6 CEP16816.1 - 2.3e-16 59.7 0.0 1.8e-09 37.6 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 CEP16816.1 - 4.2e-08 32.9 0.3 0.00021 21.3 0.0 4.0 3 1 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 CEP16816.1 - 7e-08 32.4 0.0 0.00011 22.2 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 CEP16816.1 - 4.3e-06 26.3 0.1 1.6e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEP16816.1 - 0.0014 18.3 0.0 3 7.6 0.0 3.5 3 0 0 3 3 3 1 PPR repeat Trehalase PF01204.18 CEP16818.1 - 2e-176 587.8 0.6 2.4e-176 587.5 0.6 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CEP16818.1 - 1.8e-13 49.9 0.1 5.9e-13 48.3 0.1 1.9 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cyclin PF08613.11 CEP16819.1 - 1.8e-41 142.2 0.1 3.2e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP16819.1 - 0.0015 18.3 0.1 0.0033 17.2 0.1 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain A_amylase_inhib PF01356.19 CEP16819.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Alpha amylase inhibitor Apis_Csd PF11671.8 CEP16820.1 - 2.1 8.3 8.5 1.5 8.8 7.3 1.3 1 1 0 1 1 1 0 Complementary sex determiner protein MAS20 PF02064.15 CEP16820.1 - 9.5 6.3 9.1 13 5.9 9.1 1.4 1 1 0 1 1 1 0 MAS20 protein import receptor TM2 PF05154.16 CEP16826.1 - 1.3e-15 57.4 7.5 2.6e-15 56.5 7.5 1.4 1 0 0 1 1 1 1 TM2 domain RRM_1 PF00076.22 CEP16827.1 - 1.3e-18 66.6 0.0 2.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 CEP16828.1 - 1.6e-15 57.1 0.7 2.1e-14 53.6 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP16828.1 - 2.1e-07 31.0 0.1 6.6e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CEP16828.1 - 7.4e-07 28.8 0.6 4e-05 23.2 0.3 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 CEP16828.1 - 1.1e-05 24.9 0.5 0.0002 20.8 0.2 2.2 2 0 0 2 2 2 1 AIG1 family IIGP PF05049.13 CEP16828.1 - 9.6e-05 21.6 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CEP16828.1 - 0.001 19.2 0.0 0.28 11.4 0.1 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CEP16828.1 - 0.018 15.5 0.0 0.097 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 CEP16828.1 - 0.025 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Septin Ras PF00071.22 CEP16828.1 - 0.053 13.1 0.2 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Ras family MMR_HSR1_Xtn PF16897.5 CEP16828.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PduV-EutP PF10662.9 CEP16828.1 - 0.13 12.0 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CEP16828.1 - 0.22 11.6 8.8 0.45 10.6 0.2 2.9 2 1 1 3 3 2 0 Dynamin family Telomerase_RBD PF12009.8 CEP16829.1 - 1.7e-36 125.3 11.8 1.5e-35 122.2 5.6 3.4 2 1 1 3 3 3 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CEP16829.1 - 1.5e-12 47.6 1.5 1.7e-07 31.0 0.1 3.3 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) CIA30 PF08547.12 CEP16831.1 - 3.7e-46 157.0 0.0 4.5e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 CEP16831.1 - 0.0056 16.6 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain RVT_1 PF00078.27 CEP16833.1 - 6.8e-16 58.4 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIR2 PF02146.17 CEP16835.1 - 6.3e-38 130.5 0.0 9.3e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CEP16835.1 - 0.0061 16.3 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zf-CCCH_2 PF14608.6 CEP16836.1 - 7.6e-07 29.4 20.3 0.00022 21.6 1.0 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PAM2 PF07145.15 CEP16836.1 - 0.035 13.8 0.3 0.07 12.9 0.3 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-CCCH PF00642.24 CEP16836.1 - 0.039 13.9 8.9 0.79 9.7 7.9 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Disintegrin PF00200.23 CEP16836.1 - 0.3 11.9 5.1 0.83 10.5 5.1 1.7 1 0 0 1 1 1 0 Disintegrin zf-CCCH_4 PF18044.1 CEP16836.1 - 0.48 10.3 10.6 2.5 8.0 9.6 2.3 1 1 1 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEP16836.1 - 0.71 10.0 9.0 0.16 12.1 1.6 2.6 2 0 0 2 2 2 0 Zinc finger domain PAS_3 PF08447.12 CEP16838.1 - 1.3e-13 51.0 1.1 2.4e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 CEP16838.1 - 1.3e-09 38.0 0.0 1.3e-09 38.0 0.0 2.9 3 0 0 3 3 2 1 PAS fold PAS_9 PF13426.7 CEP16838.1 - 5.1e-08 33.1 0.0 2e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 PAS domain CENP-M PF11111.8 CEP16838.1 - 3.2e-07 29.7 0.7 6.1e-07 28.8 0.7 1.4 1 0 0 1 1 1 1 Centromere protein M (CENP-M) GATA PF00320.27 CEP16838.1 - 8.6e-06 25.3 2.5 1.8e-05 24.2 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger TFIIA PF03153.13 CEP16838.1 - 5.1e-05 23.5 21.3 5.1e-05 23.5 21.3 3.6 3 1 1 4 4 2 2 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CEP16838.1 - 0.00014 21.9 6.7 0.00014 21.9 6.7 3.7 3 1 1 4 4 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term eIF-3_zeta PF05091.12 CEP16838.1 - 0.004 16.2 14.7 0.004 16.2 14.7 2.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAS_4 PF08448.10 CEP16838.1 - 0.019 15.2 2.8 0.028 14.7 0.0 2.5 2 0 0 2 2 1 0 PAS fold Cyclin_N PF00134.23 CEP16838.1 - 0.086 12.6 0.1 0.086 12.6 0.1 3.3 3 0 0 3 3 2 0 Cyclin, N-terminal domain Suf PF05843.14 CEP16838.1 - 0.31 11.0 26.1 0.019 14.9 8.8 3.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Cyclin PF08613.11 CEP16838.1 - 0.62 10.4 0.0 0.62 10.4 0.0 3.5 4 0 0 4 4 4 0 Cyclin DUF4770 PF15994.5 CEP16838.1 - 1.9 8.7 20.7 0.72 10.1 7.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) SNF2_N PF00176.23 CEP16839.1 - 2.7e-72 243.4 0.8 2.7e-72 243.4 0.8 3.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP16839.1 - 2.6e-18 66.4 0.0 2.6e-18 66.4 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 CEP16839.1 - 2.9e-18 65.9 8.8 2.9e-18 65.9 8.8 4.1 5 0 0 5 5 5 1 HSA SnAC PF14619.6 CEP16839.1 - 4.8e-14 52.7 6.1 4.8e-14 52.7 6.1 4.1 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 CEP16839.1 - 7.4e-10 39.1 2.5 1.2e-09 38.4 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CEP16839.1 - 0.049 13.7 1.6 0.24 11.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 CEP16840.1 - 0.0071 16.0 7.9 0.0071 16.0 7.9 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.9 CEP16840.1 - 0.052 13.6 0.6 0.052 13.6 0.6 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CCDC106 PF15794.5 CEP16840.1 - 4.2 7.0 6.8 0.48 10.1 2.5 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Drf_GBD PF06371.13 CEP16841.1 - 2.1e-15 56.8 0.1 4.8e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain KH_1 PF00013.29 CEP16842.1 - 2e-29 101.2 0.0 1.1e-07 31.6 0.0 7.6 8 0 0 8 8 8 5 KH domain DUF4974 PF16344.5 CEP16842.1 - 0.17 11.9 1.2 0.9 9.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) ArsA_ATPase PF02374.15 CEP16843.1 - 5.3e-114 380.5 1.7 6.1e-114 380.3 1.7 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CEP16843.1 - 9.3e-14 51.7 0.1 3.3e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CEP16843.1 - 1.2e-11 44.7 0.0 2.2e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 CEP16843.1 - 5.4e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CEP16843.1 - 5.5e-06 26.0 0.5 7.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CEP16843.1 - 3.2e-05 23.5 0.0 7.7e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 CEP16843.1 - 0.00017 21.3 1.7 0.00079 19.1 0.1 2.4 2 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CEP16843.1 - 0.0035 17.0 0.0 0.014 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP16843.1 - 0.0039 16.9 0.0 0.016 14.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CEP16843.1 - 0.027 13.7 0.1 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 CEP16843.1 - 0.057 12.9 0.0 0.21 11.0 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein Zeta_toxin PF06414.12 CEP16843.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF5131 PF07505.11 CEP16843.1 - 0.11 11.9 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) AAA_18 PF13238.6 CEP16843.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 CEP16844.1 - 1.2e-39 135.8 0.1 1.6e-39 135.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP16844.1 - 6.3e-27 93.5 2.4 9.5e-27 92.9 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP16844.1 - 1.4e-14 54.1 22.1 2.5e-14 53.4 22.1 1.4 1 0 0 1 1 1 1 DnaJ central domain PDZ_6 PF17820.1 CEP16844.1 - 0.14 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Anti-TRAP PF15777.5 CEP16844.1 - 0.95 9.5 17.7 0.081 12.9 2.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein AtuA PF07287.11 CEP16845.1 - 1.4e-113 379.2 0.0 1.9e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Apyrase PF06079.11 CEP16846.1 - 0.12 11.5 1.2 2.5 7.2 0.2 2.2 2 0 0 2 2 2 0 Apyrase Ribosomal_S16 PF00886.19 CEP16847.1 - 1.7e-27 95.2 0.1 2.2e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 SPX PF03105.19 CEP16848.1 - 1.2e-34 120.9 13.6 1.8e-16 61.1 0.6 3.1 1 1 2 3 3 3 3 SPX domain Na_sulph_symp PF00939.19 CEP16848.1 - 7.1e-32 111.1 33.6 1e-31 110.5 33.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CEP16848.1 - 3.1e-25 89.0 32.4 3.1e-25 89.0 32.4 2.3 2 1 1 3 3 3 1 Citrate transporter DUF4179 PF13786.6 CEP16848.1 - 1.9 9.0 6.2 28 5.3 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) Acid_PPase PF12689.7 CEP16849.1 - 9.4e-51 172.0 0.0 1.1e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 CEP16849.1 - 0.12 12.1 0.0 1.1 9.0 0.0 2.1 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase SNAP PF14938.6 CEP16850.1 - 3.1e-69 233.5 24.0 2.1e-57 194.7 17.1 2.3 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Arrestin_N PF00339.29 CEP16850.1 - 1.8e-09 37.8 0.0 4.3e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain TPR_12 PF13424.6 CEP16850.1 - 0.0046 17.2 9.3 0.19 12.1 2.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP16850.1 - 0.06 13.6 5.6 0.066 13.4 0.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.20 CEP16850.1 - 0.092 13.5 17.3 12 7.3 0.2 6.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 CEP16850.1 - 7.3 6.6 11.8 3.1 7.8 0.1 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 CEP16851.1 - 1.7e-64 217.7 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16851.1 - 3.1e-38 131.5 0.0 4.1e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP16851.1 - 0.00058 18.7 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP16851.1 - 0.015 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CEP16851.1 - 0.026 14.5 0.0 0.25 11.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CEP16851.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CEP16851.1 - 0.091 12.3 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DDE_3 PF13358.6 CEP16852.1 - 3.6e-05 23.6 0.1 4.5e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PH_9 PF15410.6 CEP16854.1 - 4.5e-12 46.4 0.0 1.1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain HTH_Tnp_Tc3_2 PF01498.18 CEP16855.1 - 5e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CEP16855.1 - 8e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.24 CEP16857.1 - 2e-74 251.1 9.9 5.4e-74 249.7 9.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP16857.1 - 1.5e-08 34.0 16.8 6.7e-05 22.0 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_N PF00134.23 CEP16858.1 - 7.5e-09 35.4 0.1 1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP16858.1 - 4.1e-06 27.3 0.1 5.2e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin DNA_pol_A_exo1 PF01612.20 CEP16859.1 - 9.8e-08 31.9 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Astro_capsid_p PF12226.8 CEP16859.1 - 0.76 8.9 6.6 1.1 8.4 6.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 CEP16859.1 - 9.4 4.2 7.5 12 3.8 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Metallophos_2 PF12850.7 CEP16862.1 - 6.5e-19 68.7 0.0 5.4e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Hydrolase_4 PF12146.8 CEP16862.1 - 1e-17 64.3 0.0 1.7e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CEP16862.1 - 1.2e-16 61.1 0.1 3e-15 56.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP16862.1 - 3.9e-08 34.2 0.0 5.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.28 CEP16862.1 - 0.00067 20.2 0.3 0.69 10.4 0.2 2.5 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_S9 PF00326.21 CEP16862.1 - 0.0021 17.6 0.0 0.85 9.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 CEP16862.1 - 0.0073 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase NitrOD5 PF11537.8 CEP16862.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 Abhydrolase_2 PF02230.16 CEP16862.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.3 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Syja_N PF02383.18 CEP16863.1 - 5.8e-90 301.9 3.2 1.3e-89 300.7 3.2 1.6 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CEP16863.1 - 6.9e-34 116.0 0.1 1.5e-33 114.9 0.1 1.6 1 0 0 1 1 1 1 Inositol phosphatase DDE_3 PF13358.6 CEP16864.1 - 2.2e-08 33.9 0.4 1.2e-07 31.6 0.2 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP16864.1 - 3e-06 27.4 0.2 9.3e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 CEP16864.1 - 0.0029 17.6 1.0 0.14 12.3 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 CEP16864.1 - 0.0043 17.6 0.4 0.0079 16.8 0.1 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP16864.1 - 0.014 15.4 0.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_DeoR PF08220.12 CEP16864.1 - 0.072 12.8 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TrmB PF01978.19 CEP16864.1 - 0.09 12.7 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Sel1 PF08238.12 CEP16865.1 - 5e-45 150.9 12.2 4.5e-09 36.7 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_1 PF00515.28 CEP16865.1 - 0.73 9.8 8.4 4.7 7.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP16865.1 - 2.7 8.3 10.9 16 5.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP16865.1 - 6.4 7.3 8.5 33 5.0 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Tmemb_14 PF03647.13 CEP16866.1 - 5.1e-20 72.0 11.1 2.1e-19 70.0 11.1 1.7 1 1 0 1 1 1 1 Transmembrane proteins 14C cNMP_binding PF00027.29 CEP16866.1 - 0.026 14.6 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF4131 PF13567.6 CEP16866.1 - 0.95 9.1 3.6 2.2 7.9 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1768 PF08719.11 CEP16867.1 - 6.3e-05 23.3 0.1 0.00025 21.3 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1768) START PF01852.19 CEP16869.1 - 2.5e-11 43.4 0.2 4e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 START domain DUF2152 PF10222.9 CEP16870.1 - 0.08 11.3 0.0 0.084 11.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) RabGAP-TBC PF00566.18 CEP16871.1 - 6e-26 91.4 0.8 6e-26 91.4 0.8 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6_N PF17675.1 CEP16871.1 - 0.0092 16.5 49.1 0.051 14.1 4.3 5.5 3 2 1 4 4 4 3 Apg6 coiled-coil region YabA PF06156.13 CEP16871.1 - 0.62 10.7 30.9 1.4 9.6 7.9 5.2 2 2 1 3 3 3 0 Initiation control protein YabA Velvet PF11754.8 CEP16872.1 - 5.9e-73 245.9 9.7 4.6e-45 154.5 0.1 2.5 2 1 1 3 3 3 2 Velvet factor Glyco_transf_49 PF13896.6 CEP16873.1 - 3.2e-27 95.8 1.6 2.4e-21 76.4 0.2 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Pyr_redox PF00070.27 CEP16876.1 - 7.8e-13 48.8 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEP16876.1 - 1.1e-12 47.9 0.1 1.8e-11 43.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP16876.1 - 1.3e-06 27.9 0.1 3.2e-06 26.6 0.1 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEP16876.1 - 0.027 13.6 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 CEP16876.1 - 0.058 13.8 0.0 0.075 13.5 0.0 1.3 1 1 0 1 1 1 0 Putative NAD(P)-binding Sel1 PF08238.12 CEP16877.1 - 2.9e-28 97.7 14.7 2.4e-07 31.2 0.0 6.9 7 0 0 7 7 7 6 Sel1 repeat TPR_12 PF13424.6 CEP16877.1 - 5.2 7.4 7.8 2.2 8.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 CEP16878.1 - 7.1e-09 35.6 12.5 1.5e-08 34.6 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FixH PF05751.11 CEP16878.1 - 0.16 11.9 4.0 0.32 11.0 4.0 1.4 1 0 0 1 1 1 0 FixH Methyltransf_33 PF10017.9 CEP16879.1 - 9.8e-87 291.0 1.1 1.4e-86 290.5 1.1 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 CEP16879.1 - 2e-31 109.5 3.1 4.8e-16 59.1 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CEP16879.1 - 2.3e-05 24.9 0.9 2.3e-05 24.9 0.9 2.0 2 1 0 2 2 2 1 DinB superfamily TrkH PF02386.16 CEP16882.1 - 8.7e-92 308.1 7.8 1.4e-88 297.5 2.9 2.1 2 0 0 2 2 2 2 Cation transport protein CHD5 PF04420.14 CEP16882.1 - 0.037 13.9 1.6 0.11 12.3 1.6 1.8 1 0 0 1 1 1 0 CHD5-like protein YqzM PF14141.6 CEP16882.1 - 7.5 6.7 8.0 25 5.0 8.0 1.9 1 0 0 1 1 1 0 YqzM-like protein PPR_2 PF13041.6 CEP16883.1 - 1.5e-11 44.3 0.1 0.00019 21.6 0.0 4.4 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 CEP16883.1 - 2.3e-06 27.6 0.3 0.74 9.9 0.0 4.6 3 2 2 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 CEP16883.1 - 0.00016 21.7 0.5 0.16 12.3 0.0 4.8 5 1 0 5 5 5 1 PPR repeat Globin PF00042.22 CEP16883.1 - 0.14 12.7 1.1 0.8 10.3 0.0 2.6 3 0 0 3 3 3 0 Globin WD40 PF00400.32 CEP16884.1 - 1.7e-12 47.6 2.1 0.19 12.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat G-patch PF01585.23 CEP16885.1 - 1e-09 38.1 0.6 3e-09 36.6 0.6 1.8 1 0 0 1 1 1 1 G-patch domain WD40 PF00400.32 CEP16887.1 - 1.6e-19 69.9 20.0 1.8e-06 28.6 0.0 6.8 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16887.1 - 7.2e-18 64.7 9.4 1e-06 28.9 0.2 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP16887.1 - 9.9e-05 22.3 3.9 0.011 15.6 2.8 3.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP16887.1 - 0.032 13.2 0.1 0.093 11.7 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2 PF00096.26 CEP16888.1 - 3.2e-16 58.8 14.4 0.00086 19.6 0.4 5.0 3 1 1 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP16888.1 - 3.7e-08 33.5 14.6 0.13 13.2 0.3 5.4 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP16888.1 - 9.8e-05 22.6 2.2 0.15 12.4 0.2 3.0 2 1 0 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 CEP16888.1 - 0.017 15.5 2.1 0.09 13.3 0.4 4.9 5 0 0 5 5 5 0 Zinc-finger double domain CHORD PF04968.12 CEP16888.1 - 0.22 12.3 0.2 0.22 12.3 0.2 5.4 3 3 3 6 6 6 0 CHORD zf-C2H2_aberr PF17017.5 CEP16888.1 - 0.29 11.3 8.5 40 4.3 0.1 4.0 2 1 2 4 4 4 0 Aberrant zinc-finger FOXP-CC PF16159.5 CEP16888.1 - 0.46 11.2 0.1 0.46 11.2 0.1 5.2 6 1 1 7 7 7 0 FOXP coiled-coil domain Ndc1_Nup PF09531.10 CEP16888.1 - 2.7 6.6 13.6 3 6.4 13.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CEP16888.1 - 5.4 5.7 10.1 6.9 5.3 10.1 1.2 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CEP16889.1 - 5.9e-63 212.7 0.1 4.8e-37 127.7 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16889.1 - 1.4e-40 139.2 0.1 2.7e-27 95.7 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP16889.1 - 0.0027 17.1 0.0 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pex14_N PF04695.13 CEP16889.1 - 2.5 8.8 9.8 1.3 9.7 4.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_fungal PF17667.1 CEP16889.1 - 5.6 5.6 10.2 27 3.4 10.2 2.0 1 1 0 1 1 1 0 Fungal protein kinase PALP PF00291.25 CEP16890.1 - 2.4e-67 227.4 0.1 3e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CEP16890.1 - 1.5e-14 54.2 0.0 4.1e-07 30.3 0.0 3.8 3 1 0 3 3 3 2 CBS domain adh_short PF00106.25 CEP16890.1 - 0.067 12.6 0.2 2 7.8 0.0 2.5 1 1 0 2 2 2 0 short chain dehydrogenase Glyco_tran_WecB PF03808.13 CEP16890.1 - 0.068 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF3016 PF11454.8 CEP16890.1 - 0.17 11.7 0.0 0.6 9.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) ChAPs PF09295.10 CEP16892.1 - 6.3e-130 433.7 3.2 5.7e-105 351.5 0.1 3.1 2 1 1 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CEP16892.1 - 2.9e-05 24.5 3.1 0.29 11.7 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat AAT PF03417.16 CEP16892.1 - 0.041 13.6 0.2 0.069 12.8 0.2 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TPR_14 PF13428.6 CEP16892.1 - 0.071 14.0 2.7 91 4.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP16892.1 - 0.3 11.4 13.1 1.6 9.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP16892.1 - 0.31 11.3 4.6 23 5.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP16892.1 - 7 6.7 5.8 73 3.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 CEP16893.1 - 4.6e-16 58.8 0.1 1.2e-15 57.5 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEP16893.1 - 9e-09 35.6 0.0 2.3e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CEP16893.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature TetR_C_5 PF08360.11 CEP16893.1 - 0.1 12.8 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 QacR-like protein, C-terminal region Ribosomal_S10 PF00338.22 CEP16894.1 - 6.5e-29 100.1 0.5 9e-29 99.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2540 PF10802.8 CEP16894.1 - 0.041 13.9 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) MFS_1 PF07690.16 CEP16895.1 - 5.8e-33 114.3 33.1 5.3e-25 88.1 5.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP16895.1 - 3.3e-31 108.6 15.6 3.2e-28 98.8 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1279 PF06916.13 CEP16896.1 - 1.4e-17 64.0 0.4 1.7e-17 63.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DAGK_cat PF00781.24 CEP16897.1 - 3.6e-29 100.9 0.0 6.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_M3 PF01432.20 CEP16898.1 - 1.4e-121 407.0 0.0 2e-121 406.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CEP16898.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like MMM1 PF10296.9 CEP16899.1 - 6.9e-14 51.6 2.6 5.1e-11 42.2 0.6 2.6 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Metallophos PF00149.28 CEP16900.1 - 2.6e-35 122.8 0.3 4.9e-35 121.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP16900.1 - 6.2e-12 45.8 1.7 1.2e-11 44.8 1.7 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zf-H2C2_2 PF13465.6 CEP16901.1 - 1.6e-10 40.9 8.1 8.4e-08 32.3 3.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP16901.1 - 0.0004 20.7 3.9 0.0004 20.7 3.9 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CEP16901.1 - 0.0011 19.2 2.1 0.044 14.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP16901.1 - 0.015 16.1 18.0 0.017 15.9 3.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CEP16901.1 - 0.035 14.4 5.8 0.65 10.4 0.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sprouty PF05210.13 CEP16901.1 - 0.049 14.0 2.9 0.076 13.4 2.9 1.3 1 0 0 1 1 1 0 Sprouty protein (Spry) DUF2256 PF10013.9 CEP16901.1 - 0.099 12.8 6.4 0.93 9.7 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) MRP-S25 PF13741.6 CEP16902.1 - 1e-44 152.8 0.9 1.2e-44 152.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CEP16902.1 - 1.6e-06 28.4 0.3 0.042 14.1 0.1 2.9 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 Arena_RNA_pol PF06317.11 CEP16904.1 - 0.074 10.2 0.0 0.084 10.0 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase U1snRNP70_N PF12220.8 CEP16905.1 - 7.9e-26 90.5 2.2 1.9e-25 89.3 2.2 1.7 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CEP16905.1 - 1.3e-17 63.3 0.0 2.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP16905.1 - 0.0067 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IPPT PF01715.17 CEP16905.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 IPP transferase PHM7_cyt PF14703.6 CEP16905.1 - 0.055 13.7 0.6 0.089 13.0 0.6 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PAP_central PF04928.17 CEP16906.1 - 2.4e-97 324.8 0.0 3.2e-97 324.4 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CEP16906.1 - 2.3e-43 147.8 0.0 3.8e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CEP16906.1 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain RVT_1 PF00078.27 CEP16907.1 - 3.9e-30 105.0 0.1 6.3e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 CEP16908.1 - 2e-57 194.5 0.0 1.5e-37 129.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16908.1 - 4.1e-27 95.1 0.0 5.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP16908.1 - 3.5e-08 33.1 0.1 1.1e-06 28.3 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP16908.1 - 1.7e-06 27.6 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CEP16908.1 - 0.0018 18.0 0.1 0.0057 16.3 0.0 1.8 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP16908.1 - 0.0047 16.9 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP16908.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CEP16908.1 - 0.061 12.3 1.3 0.17 10.8 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain HTH_46 PF15977.5 CEP16908.1 - 0.17 11.9 1.3 0.36 10.9 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding PIP49_C PF12260.8 CEP16908.1 - 0.47 10.1 3.5 1.3 8.6 0.5 2.6 2 1 1 3 3 3 0 Protein-kinase domain of FAM69 PAG PF15347.6 CEP16909.1 - 0.0097 15.0 15.2 0.013 14.5 15.2 1.2 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched HAGH_C PF16123.5 CEP16910.1 - 3.9e-25 88.2 0.1 5.7e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CEP16910.1 - 4.5e-10 39.9 6.4 3.3e-08 33.8 6.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CEP16910.1 - 0.0082 15.7 0.4 0.031 13.8 0.4 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lum_binding PF00677.17 CEP16912.1 - 4.6e-46 154.7 4.2 8.9e-23 80.1 0.6 2.1 2 0 0 2 2 2 2 Lumazine binding domain F-box PF00646.33 CEP16913.1 - 5e-08 32.6 0.3 2e-07 30.7 0.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP16913.1 - 9.2e-08 31.9 0.9 3.8e-07 29.9 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 CEP16913.1 - 0.0037 17.1 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 F-box RRM_1 PF00076.22 CEP16914.1 - 3.8e-19 68.3 0.8 4.5e-13 48.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_5 PF07994.12 CEP16915.1 - 3.9e-148 493.1 0.0 4.6e-148 492.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CEP16915.1 - 1.3e-44 150.9 0.2 2.5e-44 150.0 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Myb_DNA-bind_7 PF15963.5 CEP16917.1 - 1.5e-24 85.7 0.3 1.5e-24 85.7 0.3 3.6 4 0 0 4 4 4 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CEP16917.1 - 2.3e-05 24.5 2.1 8.4e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF2407 PF10302.9 CEP16918.1 - 1.8e-07 31.6 0.7 4.1e-07 30.5 0.0 1.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain VWD PF00094.25 CEP16918.1 - 0.062 13.6 2.5 0.69 10.2 2.3 2.0 1 1 1 2 2 2 0 von Willebrand factor type D domain DUF3439 PF11921.8 CEP16918.1 - 0.81 9.7 8.7 1.7 8.7 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MotA_ExbB PF01618.16 CEP16919.1 - 0.018 14.8 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Sds3 PF08598.11 CEP16921.1 - 5.7e-21 75.5 2.8 5.7e-21 75.5 2.8 3.4 3 1 0 3 3 3 1 Sds3-like Coat_X PF07552.11 CEP16921.1 - 3.5 7.5 5.8 1.8 8.4 1.3 2.4 2 0 0 2 2 2 0 Spore Coat Protein X and V domain Ribosomal_S28e PF01200.18 CEP16922.1 - 1.9e-33 114.2 1.1 2.2e-33 114.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 CEP16922.1 - 0.055 13.8 0.0 0.058 13.7 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal tRNA-synt_1b PF00579.25 CEP16923.1 - 8.7e-72 241.9 0.0 1.4e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SNF2_N PF00176.23 CEP16924.1 - 1.1e-46 159.2 0.6 1.1e-46 159.2 0.6 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP16924.1 - 1.2e-11 44.9 0.5 4.1e-11 43.2 0.5 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ASXH PF13919.6 CEP16925.1 - 2.4e-08 34.1 0.5 8.2e-08 32.4 0.5 1.9 1 1 0 1 1 1 1 Asx homology domain WD40 PF00400.32 CEP16926.1 - 1.9e-08 34.8 0.0 0.23 12.4 0.0 6.0 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP16926.1 - 2.3e-06 27.8 0.0 7.1 7.0 0.0 5.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.13 CEP16926.1 - 0.024 13.4 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region Gmad1 PF10647.9 CEP16926.1 - 0.086 12.6 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain MFS_1 PF07690.16 CEP16927.1 - 2.5e-44 151.6 31.2 3.5e-44 151.2 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP16927.1 - 2.5e-16 59.6 6.3 2.5e-16 59.6 6.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TAFH PF07531.14 CEP16927.1 - 0.075 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 NHR1 homology to TAF PTR2 PF00854.21 CEP16928.1 - 4.1e-88 295.9 11.0 4.1e-88 295.9 11.0 1.4 1 1 0 1 1 1 1 POT family FA_desaturase PF00487.24 CEP16928.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.9 3 1 0 3 3 3 0 Fatty acid desaturase RT_RNaseH PF17917.1 CEP16930.1 - 1.9e-35 121.3 0.0 1.7e-34 118.3 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP16930.1 - 2e-33 114.4 0.0 5.3e-33 113.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP16930.1 - 1.5e-21 77.0 0.0 2.7e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP16930.1 - 3.4e-16 59.1 0.1 8.2e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CEP16930.1 - 2.1e-06 28.3 0.0 6.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP16930.1 - 2.6e-05 24.7 0.0 0.0001 22.8 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 CEP16930.1 - 0.002 18.1 3.0 0.002 18.1 3.0 3.1 2 1 1 3 3 3 1 Zinc knuckle zf-H2C2 PF09337.10 CEP16930.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger SR-25 PF10500.9 CEP16930.1 - 0.46 10.1 19.3 1.1 8.8 13.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_4 PF12763.7 CEP16933.1 - 2.6e-30 104.4 0.1 2.9e-19 68.9 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CEP16933.1 - 9.2e-06 24.9 0.0 0.018 14.6 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CEP16933.1 - 2.6e-05 24.6 0.0 0.022 15.2 0.0 3.2 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.11 CEP16933.1 - 0.0021 18.4 21.1 0.0092 16.4 20.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) EF-hand_6 PF13405.6 CEP16933.1 - 0.0063 16.4 0.1 2.1 8.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain APG6_N PF17675.1 CEP16933.1 - 0.022 15.3 1.6 0.022 15.3 1.6 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region EF-hand_8 PF13833.6 CEP16933.1 - 0.023 14.5 0.1 1.1 9.1 0.0 3.0 4 0 0 4 4 4 0 EF-hand domain pair Cnn_1N PF07989.11 CEP16933.1 - 0.075 13.2 12.2 1 9.6 0.1 3.8 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 E3_binding PF02817.17 CEP16933.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain DUF4201 PF13870.6 CEP16933.1 - 0.62 9.8 13.3 0.06 13.1 1.4 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Peptidase_M3 PF01432.20 CEP16934.1 - 3.9e-125 418.7 0.0 5.7e-125 418.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 INTS5_N PF14837.6 CEP16934.1 - 0.11 12.1 0.6 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus PX PF00787.24 CEP16935.1 - 1.6e-23 82.8 1.8 4.5e-23 81.4 1.8 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CEP16935.1 - 0.0035 16.9 6.5 0.0066 16.0 6.5 1.4 1 0 0 1 1 1 1 Vps5 C terminal like HDA2-3 PF11496.8 CEP16935.1 - 0.024 13.8 6.4 0.24 10.5 0.1 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 ELFV_dehydrog PF00208.21 CEP16936.1 - 4.6e-58 196.8 0.1 7.6e-58 196.1 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEP16936.1 - 1.8e-24 85.5 0.5 9.6e-18 63.2 0.1 2.4 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase Ribosomal_60s PF00428.19 CEP16937.1 - 1.6e-16 60.6 14.1 1.9e-16 60.4 14.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein FlaC_arch PF05377.11 CEP16938.1 - 0.013 15.9 2.7 1.2 9.6 0.5 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TetR_C_13 PF16925.5 CEP16938.1 - 0.03 14.3 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Not3 PF04065.15 CEP16938.1 - 0.08 12.4 17.9 0.2 11.0 8.3 3.0 2 1 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component PhoQ_Sensor PF08918.10 CEP16938.1 - 0.11 12.4 2.7 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 PhoQ Sensor Bestrophin PF01062.21 CEP16938.1 - 0.11 11.8 0.2 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Spectrin PF00435.21 CEP16938.1 - 0.13 12.7 5.0 6.7 7.2 0.9 3.1 2 1 1 3 3 3 0 Spectrin repeat Lzipper-MIP1 PF14389.6 CEP16938.1 - 0.27 11.6 4.3 0.65 10.3 0.2 3.6 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 NleF_casp_inhib PF16809.5 CEP16938.1 - 0.33 10.8 6.2 2 8.3 4.8 2.5 1 1 1 2 2 2 0 NleF caspase inhibitor NPV_P10 PF05531.12 CEP16938.1 - 0.35 11.4 10.5 0.1 13.1 1.2 3.5 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 CEP16938.1 - 0.45 10.8 3.8 4.7 7.5 0.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 CEP16938.1 - 1.7 8.6 8.1 4.8 7.2 0.4 3.6 3 0 0 3 3 3 0 Sec20 Glyco_transf_15 PF01793.16 CEP16939.1 - 1.7e-118 395.6 15.2 2.1e-118 395.3 15.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CRAL_TRIO PF00650.20 CEP16940.1 - 3.4e-28 98.4 0.0 4.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CEP16940.1 - 7.9e-05 22.8 0.0 0.00024 21.2 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Ribonuc_red_sm PF00268.21 CEP16941.1 - 3.1e-116 387.7 2.1 3.6e-116 387.5 2.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.21 CEP16942.1 - 9.6e-114 379.6 1.9 1.1e-113 379.3 1.9 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Dmd PF17587.2 CEP16942.1 - 1.3 9.4 4.9 0.53 10.7 0.4 2.5 3 0 0 3 3 3 0 Discriminator of mRNA degradation Sugar_tr PF00083.24 CEP16943.1 - 8.3e-96 321.6 22.7 7.5e-49 166.8 13.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP16943.1 - 3.7e-24 85.3 20.6 8.7e-22 77.5 10.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.6 CEP16943.1 - 2.8 7.6 5.1 1.8 8.2 2.2 2.1 2 0 0 2 2 2 0 Kinocilin protein Pkinase PF00069.25 CEP16944.1 - 2.2e-66 224.0 0.0 3e-64 216.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP16944.1 - 1.2e-33 116.5 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP16944.1 - 4e-05 23.1 0.0 9.3e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP16944.1 - 0.027 13.8 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP16944.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_16 PF00722.21 CEP16945.1 - 1.4e-07 31.2 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Csc2 PF18320.1 CEP16945.1 - 0.022 13.7 0.2 0.023 13.7 0.2 1.0 1 0 0 1 1 1 0 Csc2 Crispr Glyco_hydro_16 PF00722.21 CEP16946.1 - 2.9e-32 111.6 1.1 4.2e-32 111.0 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Redoxin PF08534.10 CEP16947.1 - 2e-29 102.2 0.0 2.3e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CEP16947.1 - 3e-08 33.6 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family NAD_binding_10 PF13460.6 CEP16947.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 1 1 2 2 2 0 NAD(P)H-binding Methyltransf_28 PF02636.17 CEP16948.1 - 2.3e-25 89.7 0.0 3.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RasGAP PF00616.19 CEP16949.1 - 1.2e-57 195.0 5.4 1.8e-57 194.4 0.0 3.2 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase UPF0220 PF05255.11 CEP16949.1 - 1.7e-46 157.8 1.7 2.7e-46 157.1 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RasGAP_C PF03836.15 CEP16949.1 - 3.8e-37 127.5 1.6 3.8e-37 127.5 1.6 2.1 2 0 0 2 2 2 1 RasGAP C-terminus DUF4600 PF15372.6 CEP16949.1 - 0.016 15.6 2.4 0.22 12.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) GABP-alpha PF11620.8 CEP16949.1 - 0.051 13.8 0.5 16 5.8 0.1 3.1 2 0 0 2 2 2 0 GA-binding protein alpha chain MarR PF01047.22 CEP16949.1 - 0.072 13.0 0.2 18 5.4 0.0 2.9 2 0 0 2 2 2 0 MarR family Tsg PF04668.12 CEP16950.1 - 6 7.6 7.5 79 3.9 5.1 2.5 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Ank_2 PF12796.7 CEP16951.1 - 1.3e-10 41.7 4.2 7e-05 23.3 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP16951.1 - 9.2e-10 38.9 0.9 0.018 15.6 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP16951.1 - 1.3e-06 28.6 0.9 0.0012 19.2 0.2 3.5 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 CEP16951.1 - 0.00017 21.4 3.3 0.00099 18.9 0.3 3.3 2 2 0 2 2 2 1 KilA-N domain Ank_3 PF13606.6 CEP16951.1 - 0.00022 21.4 0.3 0.049 14.2 0.0 3.6 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.6 CEP16951.1 - 0.00055 20.2 2.7 0.68 10.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) CENP-F_leu_zip PF10473.9 CEP16951.1 - 0.12 12.4 11.7 0.45 10.5 3.6 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T3SS_needle_E PF08988.10 CEP16951.1 - 0.96 9.7 5.9 2.9 8.1 5.9 1.8 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle TMF_TATA_bd PF12325.8 CEP16951.1 - 1 9.6 11.3 0.96 9.7 5.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 CEP16951.1 - 1.8 8.8 12.6 6.9 6.9 4.7 3.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 CEP16951.1 - 1.9 9.2 6.9 19 6.0 2.1 3.0 2 0 0 2 2 2 0 Initiation control protein YabA EMP24_GP25L PF01105.24 CEP16951.1 - 3 7.8 5.9 1.5 8.8 1.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 CEP16951.1 - 4.1 7.9 11.1 1.1e+02 3.3 0.1 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 CEP16951.1 - 5.4 7.1 8.8 2.9 8.0 3.9 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.21 CEP16951.1 - 8.1 7.0 12.7 3.2 8.3 5.6 2.5 2 0 0 2 2 2 0 Spectrin repeat BHD_3 PF10405.9 CEP16952.1 - 4e-25 88.0 0.0 1.3e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CEP16952.1 - 4.2e-20 71.9 1.8 4.2e-20 71.9 1.8 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 CEP16952.1 - 5.8e-18 64.5 0.3 1.9e-17 62.8 0.1 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CEP16952.1 - 2.1e-13 51.0 0.2 2.1e-13 51.0 0.2 3.6 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CEP16952.1 - 5.4e-06 26.8 0.0 1.6e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily NPR3 PF03666.13 CEP16952.1 - 0.66 8.7 8.3 1.1 8.0 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FYDLN_acid PF09538.10 CEP16952.1 - 3.7 8.3 13.9 13 6.5 13.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Bmt2 PF11968.8 CEP16953.1 - 2.6e-39 135.4 0.0 3.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CEP16953.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Nt_Gln_amidase PF09764.9 CEP16954.1 - 1.7e-47 161.4 0.3 2e-47 161.2 0.3 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase RHD_dimer PF16179.5 CEP16954.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Rel homology dimerisation domain Cullin_Nedd8 PF10557.9 CEP16956.1 - 0.17 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Cullin protein neddylation domain Helitron_like_N PF14214.6 CEP16961.1 - 1.5e-18 67.7 0.7 4.7e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP16961.1 - 2.9e-17 62.9 0.0 7.5e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 CEP16961.1 - 2e-09 37.2 0.0 4.6e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CEP16961.1 - 8.2e-07 29.5 0.0 1.5e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEP16961.1 - 2.1e-06 27.6 0.0 9.3e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CEP16961.1 - 3.5e-05 22.0 0.0 0.14 10.1 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 CEP16961.1 - 0.00025 21.3 0.0 0.0012 19.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP16961.1 - 0.00028 20.7 0.2 0.067 12.9 0.2 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CEP16961.1 - 0.0061 17.0 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CEP16961.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 CEP16961.1 - 0.04 14.0 0.0 0.04 14.0 0.0 3.6 4 1 0 4 4 4 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 CEP16961.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Transposase_21 PF02992.14 CEP16963.1 - 1.8e-05 24.1 0.0 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 C9orf72-like PF15019.6 CEP16965.1 - 0.0011 18.6 1.9 0.0021 17.6 0.3 2.0 2 0 0 2 2 2 1 C9orf72-like protein family Kinesin PF00225.23 CEP16969.1 - 1.6e-100 336.3 0.1 1.6e-100 336.3 0.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP16969.1 - 2.8e-23 82.5 0.0 2.8e-23 82.5 0.0 3.4 3 0 0 3 3 3 1 Microtubule binding ATG16 PF08614.11 CEP16969.1 - 0.021 15.1 0.5 0.021 15.1 0.5 6.1 5 2 0 5 5 5 0 Autophagy protein 16 (ATG16) Ntox35 PF15534.6 CEP16969.1 - 0.031 14.7 1.6 3.3 8.2 0.1 2.8 2 0 0 2 2 2 0 Bacterial toxin 35 Ras PF00071.22 CEP16971.1 - 4.7e-11 42.6 0.1 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CEP16971.1 - 2.1e-08 34.4 0.4 3.1e-06 27.4 0.1 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP16971.1 - 0.086 12.3 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Na_H_Exchanger PF00999.21 CEP16972.1 - 6.9e-60 202.8 25.4 9.2e-60 202.4 25.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 CEP16972.1 - 0.45 9.4 18.1 0.0057 15.6 6.9 2.6 1 1 1 2 2 2 0 Carbon starvation protein CstA YrhC PF14143.6 CEP16972.1 - 0.88 9.7 3.6 0.72 10.0 0.3 2.6 2 0 0 2 2 2 0 YrhC-like protein Phage_holin_3_3 PF16083.5 CEP16972.1 - 1.5 9.0 10.1 1.9 8.6 0.2 3.4 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III Na_Pi_cotrans PF02690.15 CEP16972.1 - 6.3 6.9 7.9 1.9 8.6 2.1 2.8 2 1 0 2 2 2 0 Na+/Pi-cotransporter zf-MYND PF01753.18 CEP16973.1 - 6.8e-07 29.3 20.0 1.8e-06 27.9 20.0 1.8 1 1 0 1 1 1 1 MYND finger TFIIA PF03153.13 CEP16973.1 - 0.14 12.2 15.7 0.31 11.0 9.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RTX_C PF08339.10 CEP16973.1 - 3.7 7.6 5.4 15 5.6 1.1 2.2 2 0 0 2 2 2 0 RTX C-terminal domain Ecl1 PF12855.7 CEP16973.1 - 4.5 8.4 28.3 3.5 8.8 6.0 3.3 2 1 1 3 3 3 0 ECL1/2/3 zinc binding proteins DNA_pol_A_exo1 PF01612.20 CEP16976.1 - 0.0011 18.7 0.1 0.073 12.8 0.0 2.4 1 1 1 2 2 2 2 3'-5' exonuclease DUF4449 PF14613.6 CEP16977.1 - 0.034 14.3 2.0 0.038 14.1 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) ATP-synt_10 PF05176.14 CEP16978.1 - 0.057 12.7 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 ATP10 protein DUF572 PF04502.13 CEP16979.1 - 4.3e-38 131.8 5.3 5.9e-38 131.3 5.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1676 PF07898.13 CEP16979.1 - 0.089 12.8 2.0 0.11 12.5 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) CAS_C PF12026.8 CEP16979.1 - 0.26 11.4 6.3 0.51 10.4 6.3 1.4 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain WD40 PF00400.32 CEP16980.1 - 4.6e-29 100.0 9.8 1.6e-07 31.9 0.1 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Bromodomain PF00439.25 CEP16980.1 - 1.9e-11 43.9 0.2 4.7e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 CEP16980.1 - 1.2e-09 38.3 0.5 0.084 13.2 0.0 5.1 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP16980.1 - 0.00017 20.6 0.8 1.5 7.7 0.0 4.3 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Med31 PF05669.12 CEP16980.1 - 0.1 12.6 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 SOH1 Auxin_resp PF06507.13 CEP16980.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Auxin response factor Rib_5-P_isom_A PF06026.14 CEP16981.1 - 5.7e-61 205.1 0.1 6.9e-61 204.8 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CEP16981.1 - 0.0002 21.3 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 CEP16981.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DUF1522 PF07482.11 CEP16981.1 - 0.068 13.5 0.1 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) RibD_C PF01872.17 CEP16982.1 - 2e-31 109.4 0.0 2.3e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Linker_histone PF00538.19 CEP16983.1 - 2.8e-25 88.5 0.1 2.8e-25 88.5 0.1 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family MbeD_MobD PF04899.12 CEP16984.1 - 0.0011 19.1 8.6 0.59 10.3 0.1 4.6 4 1 1 5 5 5 2 MbeD/MobD like LPP PF04728.13 CEP16984.1 - 0.0015 18.9 16.5 1.5 9.3 0.2 6.5 6 0 0 6 6 6 2 Lipoprotein leucine-zipper rve PF00665.26 CEP16984.1 - 0.013 15.7 0.4 0.21 11.8 0.0 2.9 3 1 0 3 3 3 0 Integrase core domain MRFAP1 PF15155.6 CEP16984.1 - 0.14 12.7 1.9 2.2 8.8 0.6 2.8 2 1 0 2 2 2 0 MORF4 family-associated protein1 YtxH PF12732.7 CEP16984.1 - 1.5 9.4 12.2 15 6.2 1.0 5.4 3 1 0 3 3 3 0 YtxH-like protein Bap31_Bap29_C PF18035.1 CEP16984.1 - 1.6 8.8 0.0 1.6 8.8 0.0 5.1 6 2 0 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATG16 PF08614.11 CEP16984.1 - 2.1 8.5 42.4 0.38 10.9 5.6 5.2 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DASH_Dad3 PF08656.10 CEP16984.1 - 3 8.0 23.9 3.6 7.7 5.2 5.8 5 1 0 5 5 5 0 DASH complex subunit Dad3 DUF3450 PF11932.8 CEP16984.1 - 3.3 6.9 37.0 1.3 8.3 2.8 4.9 3 2 2 5 5 5 0 Protein of unknown function (DUF3450) SapB_1 PF05184.15 CEP16984.1 - 3.7 7.7 8.3 1.7 8.8 0.2 4.3 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF1664 PF07889.12 CEP16984.1 - 3.9 7.5 28.3 2.4 8.2 0.7 6.4 4 2 3 7 7 7 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 CEP16984.1 - 5.9 6.3 36.6 0.015 14.8 6.4 4.7 1 1 3 5 5 5 0 Golgin subfamily A member 5 BRICHOS PF04089.14 CEP16984.1 - 10 6.5 7.9 4.3 7.7 0.4 4.0 3 2 1 4 4 4 0 BRICHOS domain MFS_1 PF07690.16 CEP16985.1 - 6.9e-15 54.8 39.5 6.9e-15 54.8 39.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily zf_CCCH_4 PF18345.1 CEP16985.1 - 0.017 15.1 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Zinc finger domain BCHF PF07284.11 CEP16985.1 - 0.04 13.9 5.1 0.045 13.8 0.3 2.6 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) BRCT_2 PF16589.5 CEP16988.1 - 4.6e-12 46.2 0.0 9.4e-07 29.2 0.0 3.5 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CEP16988.1 - 5.3e-10 39.5 2.0 6.9e-06 26.4 0.0 3.6 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PilP PF04351.13 CEP16988.1 - 1 9.3 4.5 2.6 8.0 4.5 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP CPSase_L_D2 PF02786.17 CEP16989.1 - 2.2e-76 256.1 0.1 4.1e-76 255.2 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CEP16989.1 - 2.8e-45 153.4 1.3 5.5e-45 152.4 0.3 2.1 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP16989.1 - 9.2e-36 122.2 0.0 1.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CEP16989.1 - 2.5e-16 59.2 1.6 8.6e-16 57.5 1.2 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CEP16989.1 - 3e-10 40.0 0.1 6.7e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CEP16989.1 - 1.6e-06 27.8 0.2 0.00045 20.0 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CEP16989.1 - 4.6e-06 26.3 0.5 2.6e-05 23.9 0.2 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEP16989.1 - 3.5e-05 23.9 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CEP16989.1 - 8.3e-05 23.2 0.4 0.46 11.2 0.1 3.2 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.11 CEP16989.1 - 0.00074 19.2 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 CEP16989.1 - 0.0054 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 CEP16989.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp polyprenyl_synt PF00348.17 CEP16990.1 - 3.7e-65 219.5 0.1 4.6e-65 219.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase IBN_N PF03810.19 CEP16990.1 - 0.083 12.8 0.7 0.23 11.4 0.7 1.8 1 1 0 1 1 1 0 Importin-beta N-terminal domain SPC25 PF06703.11 CEP16991.1 - 0.029 14.2 0.6 0.067 13.0 0.6 1.7 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sel1 PF08238.12 CEP16992.1 - 7.6e-107 347.3 57.0 1.8e-10 41.2 0.0 15.7 15 0 0 15 15 15 14 Sel1 repeat NUC194 PF08163.12 CEP16992.1 - 3.1e-39 135.0 5.5 3.1e-39 135.0 5.5 1.9 2 0 0 2 2 2 1 NUC194 domain Feld-I_B PF09252.10 CEP16992.1 - 0.00043 20.2 0.3 3.7 7.6 0.0 4.0 3 0 0 3 3 3 2 Allergen Fel d I-B chain HEAT PF02985.22 CEP16992.1 - 0.038 14.2 0.1 4.8 7.7 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat TPR_6 PF13174.6 CEP16992.1 - 0.16 12.6 9.9 1.9 9.3 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 CEP16993.1 - 6.3e-56 190.0 0.0 1.4e-55 188.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CEP16993.1 - 1.5e-10 40.7 0.1 9.2e-10 38.2 0.0 2.3 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 CEP16993.1 - 9.1e-05 21.8 0.8 0.34 10.1 0.7 2.8 2 0 0 2 2 2 2 FAT domain 3-HAO PF06052.12 CEP16994.1 - 3.5e-38 130.6 0.2 4.1e-38 130.4 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CEP16994.1 - 0.0041 16.8 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 CEP16994.1 - 0.037 14.2 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family RFC1 PF08519.12 CEP16995.1 - 8.5e-51 172.2 0.0 2.3e-48 164.3 0.0 2.7 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CEP16995.1 - 2.4e-12 47.4 0.0 7e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CEP16995.1 - 9.3e-10 38.8 0.0 3.1e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CEP16995.1 - 6.8e-07 29.4 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CEP16995.1 - 0.00015 22.1 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CEP16995.1 - 0.00058 19.7 0.3 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 CEP16995.1 - 0.0014 19.2 0.0 0.0045 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEP16995.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CEP16995.1 - 0.011 15.6 0.0 0.042 13.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CEP16995.1 - 0.014 15.8 0.0 0.051 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CEP16995.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CEP16995.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 CEP16995.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CEP16995.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEP16995.1 - 0.061 13.4 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain NDK PF00334.19 CEP16996.1 - 6e-53 178.5 0.0 7.1e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DDE_3 PF13358.6 CEP16997.1 - 5.7e-25 87.8 0.3 4.1e-16 59.1 0.0 2.9 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP16997.1 - 1.3e-06 28.1 0.3 3.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP16997.1 - 2.7e-06 27.9 0.0 2.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP16997.1 - 7.5e-06 26.0 2.0 7.9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP16997.1 - 3.8e-05 23.6 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CEP16997.1 - 0.0025 18.1 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.15 CEP16997.1 - 0.0069 16.4 0.1 4.3 7.5 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 CEP16997.1 - 0.035 14.3 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 CEP16997.1 - 0.038 13.9 0.2 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Terminase_5 PF06056.12 CEP16997.1 - 0.052 13.4 0.0 0.052 13.4 0.0 2.8 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) DUF1804 PF08822.11 CEP16997.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Mito_carr PF00153.27 CEP16998.1 - 6.5e-54 179.8 7.8 9.5e-22 76.7 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SUIM_assoc PF16619.5 CEP16999.1 - 0.018 15.1 11.2 2.1 8.5 5.4 3.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Trp_repressor PF01371.19 CEP16999.1 - 0.12 12.5 0.1 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein EHN PF06441.12 CEP17000.1 - 3e-24 85.5 3.7 3e-24 85.5 3.7 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CEP17000.1 - 2.4e-17 63.4 0.2 4.2e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP17000.1 - 5.9e-07 30.3 0.1 1.2e-06 29.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Menin PF05053.13 CEP17001.1 - 0.0075 14.7 14.9 0.01 14.3 14.9 1.0 1 0 0 1 1 1 1 Menin BRF1 PF07741.13 CEP17001.1 - 0.0079 16.5 14.2 0.42 11.0 4.3 2.4 2 0 0 2 2 2 2 Brf1-like TBP-binding domain DUF3824 PF12868.7 CEP17001.1 - 0.023 15.4 6.6 0.035 14.8 1.3 2.4 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) AP3D1 PF06375.11 CEP17001.1 - 0.072 13.3 28.3 1.1 9.5 7.3 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 BUD22 PF09073.10 CEP17001.1 - 0.083 12.2 27.4 0.12 11.7 27.4 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_S49_N PF08496.10 CEP17001.1 - 0.1 12.7 16.7 0.26 11.3 2.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4604 PF15377.6 CEP17001.1 - 0.55 10.6 29.1 1.5 9.2 15.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) U3_snoRNA_assoc PF08297.11 CEP17001.1 - 1.2 9.9 17.0 2.8 8.7 4.2 2.6 2 0 0 2 2 2 0 U3 snoRNA associated PBP_sp32 PF07222.12 CEP17001.1 - 3.2 7.1 8.3 0.46 9.9 2.1 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DUF4770 PF15994.5 CEP17001.1 - 3.2 8.0 13.0 8.9 6.5 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) SGT1 PF07093.11 CEP17001.1 - 8.2 4.7 17.2 13 4.1 17.2 1.2 1 0 0 1 1 1 0 SGT1 protein Tyr-DNA_phospho PF06087.12 CEP17002.1 - 1.8e-94 317.1 1.3 1.7e-93 313.9 1.3 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Esterase PF00756.20 CEP17003.1 - 5.4e-60 203.1 0.0 6.3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CEP17003.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CEP17003.1 - 1.6e-05 23.9 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CEP17003.1 - 7.7e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CEP17003.1 - 0.001 18.6 0.0 0.0086 15.6 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase PF07224.11 CEP17003.1 - 0.0037 16.3 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase PAF-AH_p_II PF03403.13 CEP17003.1 - 0.007 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CEP17003.1 - 0.033 14.8 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CEP17003.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CEP17003.1 - 0.072 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CEP17003.1 - 0.085 12.4 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 CEP17003.1 - 0.089 11.4 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 CEP17003.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3245 PF11595.8 CEP17004.1 - 2.1e-10 41.3 2.6 7.8e-10 39.4 2.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) G-patch_2 PF12656.7 CEP17004.1 - 0.05 13.7 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 G-patch domain Rap_GAP PF02145.15 CEP17005.1 - 8.3e-58 195.0 0.0 2.5e-57 193.4 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Fox-1_C PF12414.8 CEP17006.1 - 0.048 14.0 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Lzipper-MIP1 PF14389.6 CEP17007.1 - 0.015 15.6 0.5 0.025 14.9 0.1 1.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.11 CEP17007.1 - 0.02 14.9 3.8 0.044 13.8 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CENP-O PF09496.10 CEP17007.1 - 0.023 14.7 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DUF4349 PF14257.6 CEP17007.1 - 0.031 13.7 0.8 0.038 13.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) eIF3_subunit PF08597.10 CEP17008.1 - 9.7e-49 166.5 31.2 9.7e-49 166.5 31.2 2.9 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit XhlA PF10779.9 CEP17008.1 - 0.042 14.0 0.5 0.19 12.0 0.5 2.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 CEP17008.1 - 0.045 13.8 9.1 0.17 11.9 9.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IL22 PF14565.6 CEP17008.1 - 0.059 13.6 3.1 0.24 11.6 2.2 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor CorA PF01544.18 CEP17008.1 - 1.2 8.4 8.4 3.2 7.0 8.4 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 CEP17008.1 - 1.8 8.8 6.9 0.37 11.1 2.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 CEP17008.1 - 7 5.1 5.4 13 4.2 5.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Dak1 PF02733.17 CEP17010.1 - 4.5e-110 367.4 2.5 5.9e-110 367.0 2.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CEP17010.1 - 2.4e-40 138.2 0.2 4.3e-40 137.4 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain Cyclin PF08613.11 CEP17011.1 - 5.9e-07 30.0 5.0 5.9e-07 30.0 5.0 3.0 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP17011.1 - 0.0019 17.9 1.2 0.0043 16.8 0.1 2.1 1 1 0 1 1 1 1 Cyclin, N-terminal domain SUIM_assoc PF16619.5 CEP17011.1 - 0.0022 18.0 3.8 0.0022 18.0 3.8 2.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 DUF853 PF05872.12 CEP17011.1 - 0.044 12.4 0.9 2.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) CDT1_C PF16679.5 CEP17011.1 - 0.17 12.3 2.3 6.6 7.2 0.7 2.6 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Tetraspanin PF00335.20 CEP17011.1 - 1.4 8.6 3.9 1.1 9.0 0.8 2.0 2 0 0 2 2 2 0 Tetraspanin family Aminotran_1_2 PF00155.21 CEP17012.1 - 1.1e-85 287.9 0.0 1.3e-85 287.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II hnRNP_Q_AcD PF18360.1 CEP17012.1 - 0.079 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain TIG PF01833.24 CEP17013.1 - 3.6e-11 43.0 0.2 3.6e-11 43.0 0.2 3.6 4 0 0 4 4 4 1 IPT/TIG domain Ank_5 PF13857.6 CEP17013.1 - 0.0005 20.3 0.2 0.003 17.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CEP17013.1 - 0.0011 19.5 0.1 0.003 18.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP17013.1 - 0.007 16.9 0.3 0.038 14.6 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF5501 PF17605.2 CEP17013.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5501) Ank_3 PF13606.6 CEP17013.1 - 0.091 13.4 0.5 15 6.6 0.1 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 CEP17013.1 - 0.19 12.3 0.5 11 6.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Sel1 PF08238.12 CEP17014.1 - 2.1e-40 136.2 24.7 1.7e-08 34.8 0.4 7.2 7 0 0 7 7 7 7 Sel1 repeat TPR_7 PF13176.6 CEP17014.1 - 5.7e-05 22.8 9.6 2.6 8.3 0.2 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat Nucleoporin_FG PF13634.6 CEP17014.1 - 4.3 8.2 14.1 1.4 9.8 10.9 1.8 2 0 0 2 2 2 0 Nucleoporin FG repeat region PH PF00169.29 CEP17015.1 - 0.0094 16.5 0.1 0.049 14.1 0.1 2.4 1 0 0 1 1 1 1 PH domain DDE_3 PF13358.6 CEP17016.1 - 0.023 14.4 0.0 0.03 14.1 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease Glyco_transf_64 PF09258.10 CEP17017.1 - 9.7e-50 169.1 0.1 1.6e-49 168.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain TPR_1 PF00515.28 CEP17018.1 - 7.5e-44 145.8 27.0 2e-05 24.2 0.1 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP17018.1 - 1.3e-42 140.5 20.6 7.8e-05 22.5 0.0 12.0 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_11 PF13414.6 CEP17018.1 - 4.5e-35 119.1 26.6 2.6e-07 30.2 0.4 9.3 8 1 2 10 10 9 7 TPR repeat TPR_8 PF13181.6 CEP17018.1 - 2.5e-28 95.9 30.6 0.014 15.6 0.0 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 CEP17018.1 - 1.4e-26 92.9 3.9 5.7e-05 23.7 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEP17018.1 - 1.6e-23 81.3 15.9 0.011 16.0 0.0 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17018.1 - 1.2e-21 75.6 6.8 0.009 16.8 0.0 9.7 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 CEP17018.1 - 2.7e-21 75.8 16.7 1.1e-06 29.0 0.2 7.7 7 2 1 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17018.1 - 2.4e-19 69.4 20.5 1.1e-05 25.6 0.7 7.9 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_9 PF13371.6 CEP17018.1 - 1.7e-14 53.7 0.1 0.00044 20.3 0.0 6.2 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP17018.1 - 1.2e-11 43.8 9.4 0.0052 16.7 0.2 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP17018.1 - 6.5e-11 42.2 2.0 0.0015 17.9 0.0 4.2 2 1 3 5 5 5 3 MalT-like TPR region ANAPC3 PF12895.7 CEP17018.1 - 2.5e-10 40.4 7.1 0.15 12.3 0.1 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CEP17018.1 - 1.6e-07 30.9 1.6 0.29 10.3 0.0 5.0 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP17018.1 - 2.5e-06 27.2 19.6 0.0053 16.6 0.5 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 CEP17018.1 - 4.5e-06 25.9 17.2 0.0019 17.2 0.0 5.0 2 2 3 5 5 4 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 CEP17018.1 - 0.00087 19.6 11.0 0.31 11.4 0.0 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 CEP17018.1 - 0.0014 18.7 9.7 4.9 7.2 0.1 5.2 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 CEP17018.1 - 0.0014 19.1 19.5 1.7 9.5 0.1 9.1 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 CEP17018.1 - 0.014 16.0 0.0 2.3 9.1 0.1 4.6 5 0 0 5 5 2 0 Tetratricopeptide repeat Sel1 PF08238.12 CEP17018.1 - 0.016 15.8 4.0 6.6 7.6 0.0 4.4 5 0 0 5 5 3 0 Sel1 repeat TAF1_subA PF14929.6 CEP17018.1 - 0.026 14.0 0.2 0.058 12.8 0.2 1.6 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Mucin PF01456.17 CEP17018.1 - 0.028 14.4 20.0 0.052 13.5 20.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ArsR PF09824.9 CEP17018.1 - 0.03 13.9 0.0 0.19 11.3 0.0 2.4 2 1 0 2 2 2 0 ArsR transcriptional regulator SPATA3 PF15662.5 CEP17018.1 - 0.045 14.4 6.0 0.081 13.6 6.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SPESP1 PF15754.5 CEP17018.1 - 0.046 12.9 2.4 0.074 12.2 2.4 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF4192 PF13830.6 CEP17018.1 - 0.065 13.3 2.3 0.34 10.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) Amidase02_C PF12123.8 CEP17018.1 - 0.087 12.5 0.3 0.22 11.2 0.3 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase SHNi-TPR PF10516.9 CEP17018.1 - 0.15 11.5 4.2 0.29 10.6 0.0 3.4 4 0 0 4 4 4 0 SHNi-TPR ANAPC5 PF12862.7 CEP17018.1 - 0.23 11.5 8.9 15 5.7 0.5 5.1 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 5 Podoplanin PF05808.11 CEP17018.1 - 0.7 10.0 8.6 1.2 9.2 8.6 1.3 1 0 0 1 1 1 0 Podoplanin BTAD PF03704.17 CEP17018.1 - 0.71 10.3 8.3 0.93 9.9 1.2 3.8 3 2 0 3 3 3 0 Bacterial transcriptional activator domain MIT PF04212.18 CEP17018.1 - 2.5 8.2 21.4 5.3 7.2 0.7 6.7 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain DUF3439 PF11921.8 CEP17018.1 - 3 7.8 8.8 6.3 6.8 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_3 PF07720.12 CEP17018.1 - 3.4 7.7 12.8 10 6.3 1.1 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Med3 PF11593.8 CEP17018.1 - 6.6 5.8 13.5 11 5.1 13.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DDE_3 PF13358.6 CEP17019.1 - 0.0012 18.7 0.5 0.05 13.3 0.2 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease CNOT11 PF10155.9 CEP17021.1 - 6.3e-31 107.1 1.3 1.1e-30 106.4 1.3 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 SNAPc_SNAP43 PF09808.9 CEP17021.1 - 0.032 14.1 1.2 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AMP-binding PF00501.28 CEP17022.1 - 1.3e-89 300.7 0.1 3.7e-74 249.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CEP17022.1 - 8.1e-26 90.8 0.1 4.1e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CEP17022.1 - 4.8e-05 23.6 0.2 0.00027 21.2 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ribosomal_L5_C PF00673.21 CEP17023.1 - 2.4e-22 78.9 0.0 6.7e-22 77.5 0.0 1.7 1 1 1 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEP17023.1 - 3.3e-19 69.0 0.0 9.8e-19 67.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 BAG PF02179.16 CEP17025.1 - 2.4e-16 59.9 1.9 2.6e-16 59.8 0.9 1.6 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.23 CEP17025.1 - 1e-05 25.2 0.4 0.00011 21.9 0.0 2.6 3 1 0 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.6 CEP17025.1 - 3.7e-05 24.1 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DASH_Ask1 PF08655.10 CEP17025.1 - 0.014 15.2 0.2 0.052 13.4 0.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Ask1 AA_permease_2 PF13520.6 CEP17026.1 - 1e-63 215.6 56.0 1.2e-63 215.4 56.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP17026.1 - 3.1e-32 111.8 44.9 4.3e-32 111.3 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.11 CEP17026.1 - 1.4 8.0 5.6 0.5 9.5 1.5 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 ZapB PF06005.12 CEP17027.1 - 0.0042 17.5 4.8 0.005 17.3 4.8 1.1 1 0 0 1 1 1 1 Cell division protein ZapB DUF4715 PF15835.5 CEP17027.1 - 0.054 13.6 0.3 0.097 12.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) E2F_CC-MB PF16421.5 CEP17027.1 - 0.084 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain LURAP PF14854.6 CEP17027.1 - 0.1 12.6 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Pkinase PF00069.25 CEP17028.1 - 1.1e-76 257.6 0.0 1.3e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17028.1 - 2.6e-36 125.2 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP17028.1 - 0.0011 18.0 0.0 0.014 14.4 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP17028.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cpn60_TCP1 PF00118.24 CEP17029.1 - 5.7e-167 556.2 2.2 6.5e-167 556.1 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ArenaCapSnatch PF17296.2 CEP17029.1 - 0.11 11.9 0.0 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 Arenavirus cap snatching domain Myb_DNA-bind_5 PF13873.6 CEP17030.1 - 0.00016 21.7 0.4 0.00035 20.6 0.4 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CEP17030.1 - 0.0004 20.7 1.2 0.00045 20.5 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Nup54 PF13874.6 CEP17030.1 - 0.044 13.9 0.6 0.35 11.0 0.7 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Myb_DNA-bind_3 PF12776.7 CEP17030.1 - 0.1 13.6 4.3 0.15 13.0 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AMP-binding PF00501.28 CEP17031.1 - 2.8e-69 233.8 0.1 4.1e-69 233.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP17031.1 - 1.4e-11 45.2 0.6 2.8e-11 44.2 0.6 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CaM_bdg_C0 PF10562.9 CEP17031.1 - 0.077 13.1 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Peptidase_M16_C PF05193.21 CEP17032.1 - 5.6e-06 26.5 0.0 0.00032 20.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CEP17033.1 - 3.2e-08 33.2 0.1 1.1e-06 28.2 0.1 2.0 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 PH_9 PF15410.6 CEP17034.1 - 8.4e-35 119.7 0.0 3.4e-34 117.8 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 CEP17034.1 - 1.2e-32 113.1 0.2 3.2e-32 111.7 0.2 1.6 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CEP17034.1 - 2.3e-05 24.8 0.0 0.0012 19.4 0.0 2.9 1 1 0 1 1 1 1 PH domain YCII PF03795.14 CEP17034.1 - 0.091 13.2 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 YCII-related domain CTP_synth_N PF06418.14 CEP17035.1 - 1.1e-124 415.0 0.1 1.4e-124 414.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CEP17035.1 - 2.1e-58 197.3 0.0 3.5e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CEP17035.1 - 1.3e-06 28.3 0.1 4.4e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 HMG_box PF00505.19 CEP17036.1 - 3.7e-17 62.5 1.6 7.4e-17 61.5 1.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP17036.1 - 1.8e-07 31.7 0.7 5.1e-07 30.2 0.7 1.7 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 CEP17036.1 - 0.035 14.1 1.6 0.048 13.7 0.3 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV NAM-associated PF14303.6 CEP17036.1 - 4.3 8.0 12.7 0.24 12.1 2.4 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain HEM4 PF02602.15 CEP17037.1 - 3e-36 124.9 0.0 3.4e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD p450 PF00067.22 CEP17038.1 - 1.2e-40 139.7 0.4 1.4e-40 139.5 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1_DerP2_DerF2 PF02221.15 CEP17040.1 - 3.7e-21 76.0 0.7 4.6e-21 75.7 0.7 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 CEP17040.1 - 0.034 14.5 0.0 0.056 13.8 0.0 1.5 1 1 0 1 1 1 0 ML-like domain Cadherin_pro PF08758.11 CEP17040.1 - 0.089 13.0 0.0 2.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Cadherin prodomain like TOBE_2 PF08402.10 CEP17040.1 - 0.097 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TOBE domain EF-hand_4 PF12763.7 CEP17041.1 - 6.1e-37 125.7 1.5 1e-12 47.9 0.0 4.4 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CEP17041.1 - 1.4e-16 58.7 1.8 0.0077 15.7 0.0 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CEP17041.1 - 6.8e-13 48.9 1.4 3.8e-05 24.0 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEP17041.1 - 6.6e-11 41.2 3.2 0.51 10.4 0.1 5.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CEP17041.1 - 2.8e-09 36.7 0.2 0.79 9.6 0.0 5.1 4 1 1 5 5 5 3 EF-hand domain pair ATG16 PF08614.11 CEP17041.1 - 1.2e-05 25.7 19.2 1.2e-05 25.7 19.2 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 CEP17041.1 - 0.016 14.3 6.0 0.031 13.4 6.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAT1 PF06391.13 CEP17041.1 - 0.084 12.7 15.2 0.23 11.3 15.2 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 EF-hand_5 PF13202.6 CEP17041.1 - 0.12 11.9 1.0 15 5.3 0.2 3.4 4 0 0 4 4 4 0 EF hand Nup88 PF10168.9 CEP17041.1 - 1.4 6.6 10.6 2.2 6.0 10.6 1.2 1 0 0 1 1 1 0 Nuclear pore component Fzo_mitofusin PF04799.13 CEP17041.1 - 1.4 8.4 9.6 3 7.4 9.6 1.5 1 0 0 1 1 1 0 fzo-like conserved region FAM76 PF16046.5 CEP17041.1 - 3.7 6.8 12.8 7 5.9 12.8 1.4 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 CEP17041.1 - 4.4 6.6 11.9 8.9 5.6 11.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CEP17041.1 - 9.8 6.7 22.8 31 5.1 22.4 2.2 2 0 0 2 2 1 0 Apg6 coiled-coil region RT_RNaseH_2 PF17919.1 CEP17042.1 - 3.1e-27 94.5 0.0 4.3e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17042.1 - 4.6e-16 59.0 0.0 7.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP17043.1 - 9.7e-08 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP17043.1 - 3.4e-05 23.5 0.0 6.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain XRN1_D2_D3 PF18334.1 CEP17043.1 - 0.066 13.4 0.5 4.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain RT_RNaseH_2 PF17919.1 CEP17044.1 - 5.7e-34 116.2 0.0 1.2e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17044.1 - 4.2e-28 97.7 0.0 1.3e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CEP17044.1 - 8.3e-06 26.0 0.1 0.011 16.0 0.0 3.1 2 1 0 2 2 2 2 Retrotransposon gag protein RVT_1 PF00078.27 CEP17044.1 - 1.1e-05 25.0 0.1 3.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP17044.1 - 0.00051 20.6 0.1 0.0017 18.9 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 CEP17044.1 - 0.00076 19.5 2.6 0.0011 19.0 0.0 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain RVP_2 PF08284.11 CEP17044.1 - 0.0017 18.1 0.2 0.004 16.9 0.2 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CEP17044.1 - 0.002 18.1 5.5 0.0055 16.7 5.5 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF4773 PF15998.5 CEP17044.1 - 0.11 13.0 0.2 6.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4773) PIF1 PF05970.14 CEP17045.1 - 1.4e-33 116.6 0.9 5.5e-27 94.9 0.0 2.5 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CEP17045.1 - 5.8e-25 88.6 0.2 1.6e-24 87.2 0.2 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CEP17045.1 - 2.3e-19 69.9 0.0 4.3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP17045.1 - 1.5e-10 41.5 0.0 4.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CEP17045.1 - 8.2e-08 32.0 0.2 2e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Exo_endo_phos_2 PF14529.6 CEP17045.1 - 3.2e-06 27.0 0.0 1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Viral_helicase1 PF01443.18 CEP17045.1 - 4.2e-05 23.4 1.5 0.0046 16.7 0.1 3.3 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 CEP17045.1 - 0.0002 19.5 0.1 0.072 11.0 0.0 2.5 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 CEP17045.1 - 0.00025 21.4 0.0 0.0018 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEP17045.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain MDMPI_N PF11716.8 CEP17046.1 - 0.11 13.2 0.0 0.33 11.6 0.0 1.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Exo_endo_phos_2 PF14529.6 CEP17048.1 - 1.8e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CENP-Q PF13094.6 CEP17049.1 - 0.011 15.9 10.4 0.035 14.3 10.4 1.9 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Zn_Tnp_IS1 PF03811.13 CEP17049.1 - 0.086 12.6 0.6 0.48 10.2 0.6 2.3 1 0 0 1 1 1 0 InsA N-terminal domain IBR PF01485.21 CEP17049.1 - 0.095 12.9 6.6 2.7 8.3 0.6 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain LMBR1 PF04791.16 CEP17049.1 - 0.17 10.7 4.5 0.26 10.1 4.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Zn_Tnp_IS1595 PF12760.7 CEP17049.1 - 0.9 9.6 6.8 1.5 8.9 1.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF4065 PF13274.6 CEP17049.1 - 1 10.2 6.7 3.9 8.4 6.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) PHD PF00628.29 CEP17049.1 - 2.5 8.0 7.1 18 5.3 0.5 2.7 2 0 0 2 2 2 0 PHD-finger RVT_1 PF00078.27 CEP17050.1 - 3.1e-24 85.7 0.8 5e-24 85.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP17050.1 - 1.9e-09 37.4 0.2 7.7e-09 35.4 0.2 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PMBR PF09373.10 CEP17050.1 - 0.44 10.8 1.6 4 7.8 0.3 2.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat gag-asp_proteas PF13975.6 CEP17051.1 - 1.4e-07 32.0 0.1 3.6e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP17051.1 - 4.1e-06 27.4 0.1 9.6e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CEP17051.1 - 2.8e-05 24.0 1.7 6.8e-05 22.8 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 CEP17051.1 - 0.001 18.9 0.2 0.002 17.9 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 CEP17052.1 - 8.6e-30 102.7 0.0 1.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17052.1 - 4.3e-28 97.7 0.1 8.3e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP17052.1 - 8.2e-20 71.3 0.0 2.6e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP17052.1 - 1.3e-17 63.7 0.5 2.7e-17 62.6 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP17052.1 - 1.2e-07 31.8 0.1 2.7e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 CEP17052.1 - 0.00063 19.9 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 CEP17053.1 - 4e-08 33.9 0.8 4e-08 33.9 0.8 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-RVT PF13966.6 CEP17054.1 - 4.6e-08 33.7 2.3 9.4e-08 32.7 2.3 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 CEP17054.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRG PF05712.13 CEP17054.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 MRG NOA36 PF06524.12 CEP17055.1 - 0.019 14.3 9.8 0.028 13.7 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CHC2 PF01807.20 CEP17055.1 - 0.059 13.2 0.8 0.14 12.0 0.8 1.6 1 1 0 1 1 1 0 CHC2 zinc finger YL1 PF05764.13 CEP17055.1 - 0.074 13.2 13.2 0.12 12.5 13.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein zf-CCHC PF00098.23 CEP17056.1 - 0.022 14.8 12.8 0.2 11.8 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP17056.1 - 0.025 14.3 4.1 0.025 14.3 4.1 2.1 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CEP17056.1 - 3.3 7.6 17.7 1.8 8.4 7.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP17056.1 - 8.6 6.2 7.1 6.1 6.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle FAD_binding_1 PF00667.20 CEP17059.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.7 1 1 1 2 2 2 0 FAD binding domain DUF4218 PF13960.6 CEP17061.1 - 1.9e-08 33.9 1.2 3.6e-08 33.0 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2990 PF11693.8 CEP17063.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) DUF3808 PF10300.9 CEP17065.1 - 1.3e-52 179.2 3.9 2.6e-52 178.1 3.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CEP17065.1 - 0.076 13.2 2.0 32 5.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 CEP17066.1 - 5.2e-19 68.2 5.0 2e-18 66.4 0.5 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CEP17066.1 - 2.9e-06 27.2 0.0 0.00095 19.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 CEP17066.1 - 0.00026 21.0 0.6 0.01 15.9 0.3 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF4995 PF16386.5 CEP17066.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function Myosin_head PF00063.21 CEP17067.1 - 4.7e-271 900.9 1.3 9.1e-271 899.9 1.3 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CEP17067.1 - 4.5e-24 84.7 1.2 4.5e-24 84.7 1.2 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CEP17067.1 - 2.3e-11 42.4 46.2 2.7e-05 23.6 1.5 7.0 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CEP17067.1 - 0.016 15.5 0.2 0.098 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 CEP17067.1 - 0.045 13.6 2.9 0.047 13.5 1.1 2.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CEP17067.1 - 0.56 10.6 0.0 0.56 10.6 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain TSC22 PF01166.18 CEP17067.1 - 0.84 10.0 10.7 0.15 12.4 1.0 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family Lzipper-MIP1 PF14389.6 CEP17067.1 - 0.84 10.0 16.4 0.03 14.6 2.1 3.6 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GIT_CC PF16559.5 CEP17067.1 - 2 8.3 8.8 25 4.8 0.2 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 CEP17067.1 - 3 7.9 24.2 0.36 10.8 9.4 3.2 1 1 1 2 2 2 0 FlxA-like protein Cep57_CLD_2 PF14197.6 CEP17067.1 - 3.4 7.8 11.6 14 5.9 0.3 3.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 GCN5L1 PF06320.13 CEP17067.1 - 7.2 6.8 17.9 0.12 12.6 7.1 3.3 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) Peptidase_S8 PF00082.22 CEP17068.1 - 4e-32 111.7 6.7 6.7e-32 110.9 6.7 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEP17068.1 - 0.0023 18.6 0.2 0.0044 17.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Hydrolase_3 PF08282.12 CEP17068.1 - 0.061 13.1 0.3 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase OrfB_Zn_ribbon PF07282.11 CEP17069.1 - 0.00039 20.3 0.0 0.0014 18.5 0.0 1.9 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Chordopox_A13L PF05961.11 CEP17069.1 - 0.84 9.9 4.0 2.5 8.4 0.4 3.2 3 0 0 3 3 3 0 Chordopoxvirus A13L protein ToxN_toxin PF13958.6 CEP17070.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system YbjQ_1 PF01906.17 CEP17070.1 - 0.049 14.3 0.1 0.14 12.8 0.0 1.7 1 1 1 2 2 2 0 Putative heavy-metal-binding DUF1206 PF06724.11 CEP17072.1 - 0.094 12.8 1.9 5.7 7.1 1.9 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) FH2 PF02181.23 CEP17073.1 - 1.4e-67 228.4 31.3 2.5e-48 165.1 3.1 4.2 3 1 1 4 4 4 3 Formin Homology 2 Domain Drf_FH3 PF06367.16 CEP17073.1 - 2.1e-21 76.5 0.0 2.1e-21 76.5 0.0 3.5 4 1 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CEP17073.1 - 6.8e-20 71.4 0.1 6.8e-20 71.4 0.1 2.7 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Sugarporin_N PF11471.8 CEP17073.1 - 0.0082 16.1 1.5 0.27 11.2 0.0 2.7 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension TRAF_BIRC3_bd PF16673.5 CEP17073.1 - 0.041 13.7 1.0 34 4.3 0.0 4.4 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain DUF4094 PF13334.6 CEP17073.1 - 0.82 10.1 4.3 0.98 9.9 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Rimk_N PF18030.1 CEP17074.1 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RimK PreATP-grasp domain DUF2318 PF10080.9 CEP17074.1 - 0.084 13.0 0.3 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) RT_RNaseH_2 PF17919.1 CEP17075.1 - 1.3e-22 79.7 0.3 8.6e-11 41.8 0.0 3.0 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17075.1 - 6e-22 77.9 2.5 1.8e-21 76.4 0.0 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP17075.1 - 1.3e-13 51.2 0.0 2.2e-12 47.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP17075.1 - 1.8e-10 40.8 0.0 5.1e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 CEP17075.1 - 2.3e-08 33.8 3.3 6e-08 32.5 3.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 CEP17075.1 - 0.0017 18.6 0.1 0.0077 16.5 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CEP17075.1 - 0.0067 17.0 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP17075.1 - 0.0094 16.6 0.0 0.027 15.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 CEP17075.1 - 0.016 15.5 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 CEP17075.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger SAC3 PF12209.8 CEP17075.1 - 0.59 10.4 5.2 0.34 11.1 0.2 3.1 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain Tcp11 PF05794.13 CEP17077.1 - 1.7e-86 291.1 13.4 1.7e-86 291.1 13.4 3.3 2 1 1 3 3 3 2 T-complex protein 11 PfkB PF00294.24 CEP17078.1 - 8.7e-22 77.8 0.0 3.5e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ADP_PFK_GK PF04587.15 CEP17078.1 - 0.019 13.6 0.1 1.8 7.0 0.0 2.5 3 0 0 3 3 3 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Dus PF01207.17 CEP17078.1 - 0.023 13.8 0.3 0.068 12.3 0.1 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) NinB PF05772.12 CEP17078.1 - 0.043 13.6 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 NinB protein GATA PF00320.27 CEP17080.1 - 1.6e-14 53.2 5.6 1.6e-14 53.2 5.6 2.0 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP17080.1 - 0.0025 17.3 1.9 0.0049 16.4 1.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Peptidase_S10 PF00450.22 CEP17081.1 - 1.4e-51 176.3 7.1 2.6e-30 106.2 0.4 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase STE PF02200.16 CEP17083.1 - 0.069 13.6 0.4 0.31 11.5 0.4 2.1 1 1 0 1 1 1 0 STE like transcription factor Tmemb_cc2 PF10267.9 CEP17084.1 - 0.00036 19.8 10.8 0.00036 19.8 10.8 2.7 3 0 0 3 3 3 1 Predicted transmembrane and coiled-coil 2 protein HSF_DNA-bind PF00447.17 CEP17084.1 - 0.0011 19.5 0.0 0.0011 19.5 0.0 3.6 2 2 1 3 3 3 1 HSF-type DNA-binding UPF0242 PF06785.11 CEP17084.1 - 0.85 9.7 19.0 2.1 8.4 19.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SRP54 PF00448.22 CEP17085.1 - 8.1e-77 257.3 1.7 1.9e-76 256.1 1.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CEP17085.1 - 2.7e-34 117.8 4.0 2.7e-34 117.8 4.0 5.0 3 1 3 6 6 5 1 Signal peptide binding domain SRP54_N PF02881.19 CEP17085.1 - 1.7e-19 69.8 2.6 1.7e-19 69.8 2.6 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CEP17085.1 - 1.8e-07 30.9 0.2 6.2e-07 29.2 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 CEP17085.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CEP17085.1 - 0.00047 19.9 0.0 0.0015 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP17085.1 - 0.001 19.3 0.1 0.0028 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CEP17085.1 - 0.0013 17.7 2.2 0.0099 14.9 0.7 2.8 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 CEP17085.1 - 0.0019 17.6 0.1 0.31 10.4 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 CEP17085.1 - 0.0031 16.8 0.0 0.0075 15.6 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 CEP17085.1 - 0.0047 16.7 0.4 0.11 12.3 0.1 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 CEP17085.1 - 0.0074 16.2 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 CEP17085.1 - 0.014 15.3 0.2 0.052 13.5 0.1 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 CEP17085.1 - 0.016 15.6 2.3 0.025 15.0 0.4 2.4 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CEP17085.1 - 0.016 15.6 0.0 0.056 13.8 0.0 2.0 2 1 0 2 2 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 CEP17085.1 - 0.019 14.7 0.0 0.18 11.5 0.1 2.5 2 0 0 2 2 2 0 Thymidylate kinase DUF4618 PF15397.6 CEP17085.1 - 0.023 14.1 2.1 0.061 12.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) ResIII PF04851.15 CEP17085.1 - 0.032 14.2 1.5 0.05 13.6 0.3 2.1 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP17085.1 - 0.032 14.5 0.4 0.17 12.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3418 PF11898.8 CEP17085.1 - 0.041 12.6 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) MMR_HSR1 PF01926.23 CEP17085.1 - 0.041 14.0 0.2 0.38 10.9 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CEP17085.1 - 0.042 13.7 0.7 0.2 11.5 0.7 2.2 1 1 0 1 1 1 0 NTPase APS_kinase PF01583.20 CEP17085.1 - 0.048 13.6 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Adenylylsulphate kinase MipZ PF09140.11 CEP17085.1 - 0.051 12.9 0.1 1.7 7.8 0.1 2.5 1 1 0 1 1 1 0 ATPase MipZ AAA_19 PF13245.6 CEP17085.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain bZIP_C PF12498.8 CEP17085.1 - 0.26 12.3 5.2 0.11 13.5 2.0 2.0 2 0 0 2 2 1 0 Basic leucine-zipper C terminal AAA PF00004.29 CEP17085.1 - 0.83 10.1 4.5 0.86 10.0 0.2 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) YlbD_coat PF14071.6 CEP17085.1 - 3.9 7.7 6.3 5.1 7.4 0.9 3.1 1 1 1 2 2 2 0 Putative coat protein Oxysterol_BP PF01237.18 CEP17086.1 - 3.7e-67 226.8 5.3 1.8e-58 198.1 0.6 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF4407 PF14362.6 CEP17087.1 - 3 7.1 20.0 5.7 6.2 20.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 CEP17088.1 - 2.6e-16 59.9 0.0 6.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17088.1 - 8.7e-16 58.3 0.0 8e-14 51.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CEP17088.1 - 4.1e-09 37.0 0.0 1.5e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CEP17088.1 - 1.1e-06 28.8 0.0 5.1e-06 26.6 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RQC PF09382.10 CEP17088.1 - 2.5e-05 24.1 0.0 6.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 RQC domain Osmo_CC PF08946.10 CEP17088.1 - 0.024 14.9 1.9 0.065 13.5 1.9 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil LepB_GAP_N PF18172.1 CEP17088.1 - 0.14 12.1 1.6 4 7.3 1.8 2.3 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain Homeodomain PF00046.29 CEP17089.1 - 6.2e-20 70.8 1.2 1.5e-19 69.6 1.2 1.7 1 0 0 1 1 1 1 Homeodomain Apt1 PF10351.9 CEP17090.1 - 4.1e-94 316.1 8.5 4.1e-94 316.1 8.5 3.1 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 CEP17090.1 - 1.6e-91 307.6 6.0 5.5e-91 305.8 6.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CEP17090.1 - 2.5e-36 124.9 7.1 3.6e-34 117.9 0.3 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 CEP17090.1 - 2.4e-35 122.0 0.0 6.8e-35 120.5 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 CEP17090.1 - 1.1e-14 55.0 0.0 1.1e-14 55.0 0.0 3.7 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain Med30 PF11315.8 CEP17090.1 - 0.049 13.8 0.2 0.049 13.8 0.2 3.3 3 0 0 3 3 3 0 Mediator complex subunit 30 DNA_pol_E_B PF04042.16 CEP17091.1 - 1.2e-47 162.0 0.1 2e-47 161.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Cyt-b5 PF00173.28 CEP17091.1 - 1.4e-20 73.2 0.8 3e-20 72.1 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CEP17091.1 - 9.9e-13 48.6 17.2 9.9e-13 48.6 17.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Dpoe2NT PF12213.8 CEP17091.1 - 0.0086 16.4 0.3 0.029 14.6 0.3 2.0 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal DNA_pol_D_N PF18018.1 CEP17091.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain CPBP PF02517.16 CEP17091.1 - 0.55 10.6 4.5 1.2 9.5 4.5 1.5 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease Anth_synt_I_N PF04715.13 CEP17091.1 - 0.6 10.3 2.6 2 8.6 0.9 2.7 3 1 0 3 3 3 0 Anthranilate synthase component I, N terminal region Lactamase_B_2 PF12706.7 CEP17092.1 - 2.9e-08 33.5 0.0 0.001 18.6 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CEP17092.1 - 3.8e-07 29.7 0.0 9.1e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 CEP17092.1 - 6e-07 29.7 0.1 1.2e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Thiolase_N PF00108.23 CEP17093.1 - 9.7e-96 320.1 1.6 1.3e-95 319.7 1.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP17093.1 - 7e-44 148.4 0.5 7e-44 148.4 0.5 2.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEP17093.1 - 6.4e-06 25.9 3.9 1.4e-05 24.8 1.5 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEP17093.1 - 0.24 11.3 3.3 5.5 6.9 0.3 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CENP-H PF05837.12 CEP17094.1 - 3 8.3 6.3 0.86 10.0 0.6 2.4 2 1 0 3 3 3 0 Centromere protein H (CENP-H) CTD_bind PF04818.13 CEP17095.1 - 9.9e-12 45.5 0.1 3.3e-11 43.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Chs7 PF12271.8 CEP17095.1 - 0.024 14.0 0.6 1 8.7 0.1 2.1 2 0 0 2 2 2 0 Chitin synthase export chaperone 4HBT PF03061.22 CEP17095.1 - 0.027 14.8 0.2 0.052 13.9 0.2 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Glyco_transf_15 PF01793.16 CEP17096.1 - 2.3e-113 378.8 15.0 5.3e-113 377.5 10.0 2.4 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Myb_DNA-binding PF00249.31 CEP17096.1 - 7.2e-43 144.5 18.1 1.4e-15 57.2 2.3 5.5 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP17096.1 - 3.1e-34 117.0 15.0 8.6e-14 51.5 1.2 4.8 2 1 2 4 4 4 4 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CEP17096.1 - 6.3e-08 32.7 6.6 0.028 14.6 1.1 4.4 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 CEP17096.1 - 8e-06 25.7 17.1 0.0022 17.9 3.6 4.5 3 2 1 4 4 4 2 Myb DNA-binding like SLIDE PF09111.10 CEP17096.1 - 0.00028 20.9 1.7 0.00028 20.9 1.7 3.0 3 1 1 4 4 4 1 SLIDE HTH_40 PF14493.6 CEP17096.1 - 0.82 10.2 2.5 2 9.0 0.2 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Atg29_N PF18388.1 CEP17096.1 - 1.6 8.6 8.7 3.3 7.6 0.1 3.3 4 0 0 4 4 4 0 Atg29 N-terminal domain U-box PF04564.15 CEP17099.1 - 8.4e-22 77.1 0.0 1.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 CEP17099.1 - 3.3e-13 48.8 8.5 2.8e-08 33.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP17099.1 - 5.7e-11 41.7 8.5 0.0016 18.4 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 CEP17099.1 - 8.3e-10 39.3 4.4 8.3e-10 39.3 4.4 2.2 3 0 0 3 3 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 CEP17099.1 - 5.1e-08 32.5 3.1 0.0058 16.3 0.1 4.2 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 CEP17099.1 - 6.4e-07 29.1 9.2 0.00068 19.7 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP17099.1 - 8.1e-06 25.9 0.1 0.08 13.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17099.1 - 3.2e-05 24.1 1.7 0.0013 19.0 0.4 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP17099.1 - 0.00024 21.3 6.5 0.00027 21.1 1.4 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CEP17099.1 - 0.0027 18.3 0.1 1 10.0 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 CEP17099.1 - 0.014 15.6 0.0 0.06 13.5 0.0 2.1 2 0 0 2 2 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF4838 PF16126.5 CEP17099.1 - 0.021 14.2 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) TPR_19 PF14559.6 CEP17099.1 - 0.034 14.7 0.7 7 7.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat POTRA PF07244.15 CEP17099.1 - 0.059 13.9 0.2 1.8 9.2 0.0 3.3 3 1 1 4 4 4 0 Surface antigen variable number repeat TPR_7 PF13176.6 CEP17099.1 - 0.061 13.4 2.1 0.82 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP17099.1 - 0.22 12.2 2.0 8.3 7.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17099.1 - 0.44 11.5 1.9 18 6.5 0.0 4.0 4 1 0 5 5 4 0 Tetratricopeptide repeat ENTH PF01417.20 CEP17100.1 - 3.5e-48 162.8 0.1 6.2e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CEP17100.1 - 5.5e-06 25.6 0.1 5.5e-06 25.6 0.1 2.6 2 1 0 2 2 2 1 ANTH domain UIM PF02809.20 CEP17100.1 - 0.15 12.0 10.0 0.13 12.2 3.1 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif CBM_21 PF03370.13 CEP17101.1 - 3.7e-23 81.9 0.3 1e-22 80.5 0.3 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CEP17101.1 - 9.7e-09 35.7 0.1 2.6e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CDC45 PF02724.14 CEP17101.1 - 0.15 10.3 0.8 0.21 9.9 0.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 CEP17101.1 - 1.1 9.6 5.4 2.3 8.7 5.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 CEP17101.1 - 2.2 7.5 9.3 3.7 6.8 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CEP17101.1 - 3.6 7.3 5.5 7 6.3 5.5 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 CEP17101.1 - 3.9 7.9 9.1 9.7 6.7 9.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VPS13_mid_rpt PF16910.5 CEP17102.1 - 8.7e-89 297.0 21.3 2.7e-85 285.5 1.2 7.3 7 2 0 7 7 7 2 Repeating coiled region of VPS13 VPS13 PF16908.5 CEP17102.1 - 1.1e-77 261.0 0.9 1.1e-74 251.2 0.1 4.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CEP17102.1 - 3.1e-69 233.4 7.8 5.3e-68 229.3 0.1 3.6 3 1 1 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CEP17102.1 - 9.6e-67 224.2 5.0 6.8e-63 211.7 0.1 3.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CEP17102.1 - 1.4e-38 131.5 1.7 4.6e-38 129.9 1.7 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CEP17102.1 - 1.5e-07 31.7 0.0 4.2e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF5001 PF16392.5 CEP17102.1 - 0.0012 18.6 0.0 4.4 7.3 0.0 4.1 4 0 0 4 4 4 2 Ig-like domain bPH_3 PF14470.6 CEP17102.1 - 0.034 14.5 1.3 9.4 6.7 0.1 3.3 2 0 0 2 2 2 0 Bacterial PH domain BAF250_C PF12031.8 CEP17103.1 - 2.8e-06 26.8 0.7 2.8e-06 26.8 0.7 3.9 4 1 0 4 4 4 1 SWI/SNF-like complex subunit BAF250/Osa DUF4446 PF14584.6 CEP17103.1 - 6.8 6.7 8.0 0.66 10.0 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Vps51 PF08700.11 CEP17104.1 - 2.5e-13 49.9 0.4 2.5e-13 49.9 0.4 3.2 4 0 0 4 4 4 1 Vps51/Vps67 NAD_binding_2 PF03446.15 CEP17104.1 - 2.6 8.2 3.7 2.6 8.2 0.4 2.4 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase OmpH PF03938.14 CEP17104.1 - 4.1 7.7 15.1 3.9 7.8 2.2 3.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Polysacc_deac_1 PF01522.21 CEP17105.1 - 1.3e-21 76.8 0.1 2.8e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Peptidase_C14 PF00656.22 CEP17105.1 - 0.028 14.4 0.2 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Caspase domain HMG_box PF00505.19 CEP17106.1 - 1e-17 64.3 2.8 2.1e-17 63.3 2.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP17106.1 - 7.6e-09 36.0 1.3 1.5e-08 35.1 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 CEP17106.1 - 0.01 15.9 0.2 0.021 14.8 0.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Polysacc_deac_1 PF01522.21 CEP17107.1 - 6.1e-24 84.3 0.0 1.2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fimbrial PF00419.20 CEP17107.1 - 0.032 14.5 6.3 0.59 10.4 0.4 2.6 2 0 0 2 2 2 0 Fimbrial protein Ppx-GppA PF02541.16 CEP17108.1 - 8.8e-44 150.0 0.0 2e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Beta_elim_lyase PF01212.21 CEP17109.1 - 2.7e-74 250.1 0.1 3.2e-74 249.9 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CEP17109.1 - 0.001 18.5 0.0 0.012 14.9 0.0 2.3 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CEP17109.1 - 0.0057 15.9 0.0 0.014 14.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP17109.1 - 0.064 11.8 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme UvrD_C PF13361.6 CEP17110.1 - 0.015 14.7 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ACOX PF01756.19 CEP17111.1 - 2.3e-34 118.6 0.0 4.7e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CEP17111.1 - 6.5e-14 51.9 0.2 1.5e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CEP17111.1 - 1.1e-13 51.8 0.0 2.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CEP17111.1 - 0.04 14.1 0.4 0.18 12.0 0.4 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lipase_GDSL PF00657.22 CEP17112.1 - 1.2e-07 31.9 0.0 2.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP17112.1 - 2.9e-05 24.5 0.6 0.00043 20.7 0.6 2.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ParBc PF02195.18 CEP17113.1 - 3e-11 43.4 0.0 4.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain Reticulon PF02453.17 CEP17114.1 - 3.1e-22 79.2 2.0 4.7e-22 78.6 2.0 1.3 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 CEP17114.1 - 0.28 10.6 1.6 8.7 5.7 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Mito_carr PF00153.27 CEP17116.1 - 1.6e-50 169.0 1.7 3.6e-22 78.1 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein G10 PF01125.17 CEP17117.1 - 1.4e-36 125.5 0.3 1.8e-36 125.1 0.3 1.1 1 0 0 1 1 1 1 G10 protein THOC2_N PF16134.5 CEP17118.1 - 0.051 12.2 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF4112 PF13430.6 CEP17119.1 - 3.7e-27 94.7 0.7 4.9e-27 94.3 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HSA PF07529.13 CEP17120.1 - 4.6e-13 49.3 3.3 4.6e-13 49.3 3.3 6.5 7 2 0 7 7 7 1 HSA Myb_DNA-bind_6 PF13921.6 CEP17120.1 - 2.2e-07 31.0 1.2 2.2e-07 31.0 1.2 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP17120.1 - 0.00042 20.5 0.3 0.0015 18.7 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain PAS PF00989.25 CEP17121.1 - 3.8e-05 23.7 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold Rrn6 PF10214.9 CEP17122.1 - 1.3e-08 33.9 9.0 5.2e-05 22.0 7.7 2.2 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor HTH_23 PF13384.6 CEP17123.1 - 0.0051 16.6 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.6 CEP17123.1 - 0.7 10.0 3.0 0.86 9.7 0.2 2.3 2 0 0 2 2 2 0 HTH domain UBA PF00627.31 CEP17124.1 - 1.8e-31 107.6 2.9 3.1e-16 58.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 CEP17124.1 - 4.3e-20 71.2 3.9 1.6e-19 69.4 3.9 2.0 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CEP17124.1 - 1.9e-05 24.3 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.10 CEP17124.1 - 0.0003 20.5 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.6 CEP17124.1 - 0.00065 20.2 0.2 0.0018 18.9 0.1 1.7 1 1 1 2 2 2 1 MCM N-terminal domain FeoA PF04023.14 CEP17124.1 - 0.00066 19.9 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 2 FeoA domain DUF1421 PF07223.11 CEP17124.1 - 0.032 14.1 0.0 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) CUE PF02845.16 CEP17124.1 - 0.035 13.8 0.1 4 7.2 0.0 3.2 2 1 0 2 2 2 0 CUE domain TFIIA PF03153.13 CEP17124.1 - 0.038 14.0 15.7 0.047 13.7 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3306 PF11748.8 CEP17124.1 - 5.9 7.8 10.1 2.6 8.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SUIM_assoc PF16619.5 CEP17124.1 - 7.2 6.8 15.4 1.7 8.8 6.1 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 NAP PF00956.18 CEP17125.1 - 4.8e-94 314.5 9.7 4.8e-94 314.5 9.7 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Dynamin_M PF01031.20 CEP17125.1 - 0.049 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region Cwf_Cwc_15 PF04889.12 CEP17125.1 - 0.36 10.5 20.0 0.048 13.4 12.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 CEP17125.1 - 3.4 7.6 13.4 5.7 6.8 13.4 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.28 CEP17127.1 - 1.5e-05 25.0 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 CEP17128.1 - 2e-46 158.0 0.0 3.1e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17128.1 - 1.3e-30 106.0 0.0 2.5e-27 95.4 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.12 CEP17128.1 - 2.7e-26 91.7 0.0 1.9e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.15 CEP17128.1 - 1.7e-07 31.4 0.5 3.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEP17128.1 - 1.7e-05 24.3 7.6 0.0008 18.8 0.0 2.3 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CEP17128.1 - 0.0019 18.5 0.0 0.01 16.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain DnaJ PF00226.31 CEP17129.1 - 7.1e-16 58.1 0.2 1.1e-15 57.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain PrgU PF09627.10 CEP17129.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 PrgU-like protein Ribosomal_L31e PF01198.19 CEP17130.1 - 2.4e-38 130.2 2.4 3.1e-38 129.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zf-C2H2 PF00096.26 CEP17131.1 - 6.4e-19 67.3 40.0 6.5e-05 23.2 5.0 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP17131.1 - 8.9e-09 35.4 12.8 8.8e-06 25.9 2.9 5.8 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP17131.1 - 1.6e-07 31.6 47.3 0.0031 18.2 1.2 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger FOXP-CC PF16159.5 CEP17131.1 - 0.0032 18.1 3.3 0.098 13.3 0.2 4.5 4 1 1 5 5 5 2 FOXP coiled-coil domain Zip PF02535.22 CEP17131.1 - 0.011 15.0 1.9 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Ogr_Delta PF04606.12 CEP17131.1 - 0.73 9.9 6.6 23 5.1 0.3 4.3 2 2 2 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_aberr PF17017.5 CEP17131.1 - 1.8 8.6 15.9 3.3 7.8 0.2 4.1 2 2 2 4 4 4 0 Aberrant zinc-finger Citrate_bind PF16114.5 CEP17132.1 - 1.4e-89 298.3 0.2 2.7e-89 297.4 0.2 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CEP17132.1 - 1.6e-16 60.4 0.0 4e-14 52.4 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 CEP17132.1 - 2e-15 56.9 0.1 4.1e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 CEP17132.1 - 6.9e-14 52.3 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CEP17132.1 - 2.6e-07 30.4 0.0 5.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 CEP17132.1 - 1.6e-06 27.9 0.3 2.4e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain DUF4908 PF16252.5 CEP17132.1 - 0.095 12.2 0.1 17 4.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) NdhM PF10664.9 CEP17134.1 - 0.02 15.1 2.1 0.042 14.1 1.3 1.8 1 1 1 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF5071 PF16804.5 CEP17134.1 - 0.029 14.6 2.0 0.042 14.1 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5071) Laminin_II PF06009.12 CEP17134.1 - 0.11 12.5 9.9 0.24 11.4 9.9 1.6 1 0 0 1 1 1 0 Laminin Domain II Cortex-I_coil PF09304.10 CEP17134.1 - 0.67 10.2 10.0 0.047 13.9 2.9 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil NBD_C PF17042.5 CEP17134.1 - 0.71 10.4 2.0 1.2 9.6 2.0 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain HSP70 PF00012.20 CEP17134.1 - 2.6 6.1 8.4 4 5.5 8.4 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF1664 PF07889.12 CEP17134.1 - 3 7.9 8.6 2.2 8.3 5.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Muskelin_N PF06588.11 CEP17136.1 - 4.7e-74 248.6 0.4 7.6e-74 247.9 0.4 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 CEP17136.1 - 1.3e-22 79.6 4.4 1.3e-06 28.5 0.0 6.8 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CEP17136.1 - 3.4e-19 68.6 3.6 0.00015 21.7 0.3 5.6 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP17136.1 - 8.1e-15 54.1 8.4 1e-07 31.4 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CEP17136.1 - 1.9e-13 50.0 4.8 0.024 14.7 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CEP17136.1 - 1.1e-12 47.7 4.4 1.6e-05 25.0 0.1 5.1 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CEP17136.1 - 7.3e-09 35.3 5.6 0.00086 19.2 0.3 4.5 5 0 0 5 5 5 2 Kelch motif F5_F8_type_C PF00754.25 CEP17136.1 - 1.3e-05 25.4 0.1 5.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 F5/8 type C domain Zn_clus PF00172.18 CEP17137.1 - 2.5e-11 43.5 11.4 4e-11 42.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NDC10_II PF16787.5 CEP17138.1 - 0.024 13.7 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 AA_permease_2 PF13520.6 CEP17139.1 - 3.9e-62 210.5 57.4 4.5e-62 210.3 57.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP17139.1 - 7.2e-31 107.3 45.3 1.1e-30 106.7 45.3 1.2 1 0 0 1 1 1 1 Amino acid permease PDR_assoc PF08370.11 CEP17139.1 - 0.028 14.2 3.7 2.3 8.0 0.0 3.4 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Peptidase_M56 PF05569.11 CEP17139.1 - 0.26 10.5 5.1 0.17 11.1 2.7 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 RRM_1 PF00076.22 CEP17140.1 - 3.6e-27 94.0 8.5 7.7e-17 60.9 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP17140.1 - 0.044 13.9 0.0 9.1 6.5 0.0 3.4 2 1 0 2 2 2 0 RNA recognition motif FAM76 PF16046.5 CEP17140.1 - 0.55 9.5 19.2 0.16 11.3 14.0 2.0 2 0 0 2 2 2 0 FAM76 protein HTH_Tnp_IS630 PF01710.16 CEP17141.1 - 0.022 14.8 0.6 0.022 14.8 0.6 2.1 2 0 0 2 2 2 0 Transposase Npa1 PF11707.8 CEP17141.1 - 0.022 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal TMEM214 PF10151.9 CEP17141.1 - 0.077 11.5 4.3 0.1 11.1 4.3 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Ribosomal_S2 PF00318.20 CEP17141.1 - 3.3 6.9 6.2 0.3 10.3 1.1 1.7 2 0 0 2 2 2 0 Ribosomal protein S2 Clathrin PF00637.20 CEP17142.1 - 9.4e-211 690.2 50.1 1.2e-37 128.9 1.3 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CEP17142.1 - 3.6e-28 96.5 0.3 1.9e-06 27.9 0.0 6.0 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 CEP17142.1 - 7.8e-27 93.0 0.2 6.9e-26 89.9 0.1 2.9 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 CEP17142.1 - 2.7e-10 39.9 2.5 1.8e-05 24.0 0.1 3.7 3 0 0 3 3 3 2 Coatomer WD associated region Clathrin-link PF09268.10 CEP17142.1 - 3.3e-09 35.9 0.3 8e-09 34.7 0.3 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 CEP17142.1 - 0.0026 17.8 8.8 6.2 7.2 0.0 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17142.1 - 0.0035 18.0 10.7 7.8 7.6 0.0 8.5 10 1 1 11 11 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP17142.1 - 0.0041 16.9 10.2 2 8.4 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CEP17142.1 - 0.0058 17.1 10.2 2.3 8.8 0.1 6.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17142.1 - 0.0066 16.6 5.3 27 5.3 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17142.1 - 0.02 15.2 2.2 81 3.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP17142.1 - 0.085 13.1 3.0 12 6.2 0.0 4.1 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CEP17142.1 - 0.25 11.5 15.9 15 5.9 0.0 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat PPR PF01535.20 CEP17142.1 - 0.72 10.2 4.2 35 5.0 0.0 5.1 6 0 0 6 6 5 0 PPR repeat Vps39_1 PF10366.9 CEP17142.1 - 1.2 9.4 21.0 5.6 7.3 0.1 7.7 7 2 1 8 8 8 0 Vacuolar sorting protein 39 domain 1 Acyl-CoA_dh_1 PF00441.24 CEP17143.1 - 6e-46 156.4 3.8 6e-46 156.4 3.8 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEP17143.1 - 5.3e-24 85.1 0.0 2.7e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEP17143.1 - 3.4e-23 81.7 0.1 1.6e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEP17143.1 - 2.5e-20 73.1 0.9 2.5e-20 73.1 0.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain NDC10_II PF16787.5 CEP17144.1 - 3e-08 33.1 0.0 4.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 BEN PF10523.9 CEP17144.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 BEN domain Phage_integrase PF00589.22 CEP17144.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family GATA PF00320.27 CEP17145.1 - 5.5e-22 77.1 18.7 1.3e-16 59.9 5.3 2.3 2 0 0 2 2 2 2 GATA zinc finger Cytochrom_c3_2 PF14537.6 CEP17145.1 - 0.0019 18.6 10.3 0.16 12.4 2.1 2.5 2 0 0 2 2 2 2 Cytochrome c3 Elf1 PF05129.13 CEP17145.1 - 0.0087 16.1 2.7 1.7 8.7 0.6 2.6 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 CEP17145.1 - 0.029 13.9 5.9 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding NMD3 PF04981.13 CEP17145.1 - 0.093 12.2 2.3 2.6 7.4 0.1 2.2 2 0 0 2 2 2 0 NMD3 family Cytochrome_C7 PF14522.6 CEP17145.1 - 1.2 9.2 12.4 2 8.5 3.5 2.7 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrome_C554 PF13435.6 CEP17145.1 - 2.2 9.2 10.5 2.7 9.0 1.6 2.7 2 1 1 3 3 3 0 Cytochrome c554 and c-prime eIF-5_eIF-2B PF01873.17 CEP17145.1 - 2.3 8.1 9.0 11 5.9 0.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.12 CEP17145.1 - 2.5 8.7 11.8 0.38 11.3 1.2 2.6 2 1 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.10 CEP17145.1 - 5.9 7.1 10.5 4.3 7.5 0.4 2.7 3 0 0 3 3 3 0 Zinc ribbon domain F-box-like PF12937.7 CEP17146.1 - 8.1e-09 35.2 0.1 2.2e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CEP17146.1 - 7.2e-06 25.9 0.1 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 F-box F-box PF00646.33 CEP17146.1 - 6.9e-05 22.6 0.7 0.00022 21.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain RRF_GI PF12614.8 CEP17146.1 - 0.026 14.7 1.9 0.043 14.0 0.2 2.0 2 0 0 2 2 2 0 Ribosome recycling factor zf-MYND PF01753.18 CEP17147.1 - 9.1e-09 35.3 15.2 1.7e-08 34.4 15.2 1.4 1 0 0 1 1 1 1 MYND finger Sel1 PF08238.12 CEP17147.1 - 6.5e-08 33.0 11.0 0.035 14.8 0.0 6.7 8 0 0 8 8 8 3 Sel1 repeat TPR_7 PF13176.6 CEP17147.1 - 2.2 8.5 5.3 12 6.2 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17147.1 - 5.6 7.4 9.7 23 5.5 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat zf-Tim10_DDP PF02953.15 CEP17149.1 - 8.4e-22 76.6 2.0 1.2e-21 76.1 2.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.12 CEP17149.1 - 0.0056 17.1 0.0 0.0062 17.0 0.0 1.1 1 0 0 1 1 1 1 Vps54-like protein Methyltransf_11 PF08241.12 CEP17150.1 - 1.5e-06 28.8 0.0 3.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP17150.1 - 3.9e-06 27.5 0.0 1.1e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP17150.1 - 0.00018 21.4 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP17150.1 - 0.0078 16.9 0.2 0.034 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP17150.1 - 0.15 11.5 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase HTH_32 PF13565.6 CEP17151.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain PRELI PF04707.14 CEP17152.1 - 4.3e-48 163.1 0.5 5.1e-48 162.9 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family zf-MIZ PF02891.20 CEP17153.1 - 4.2e-12 45.6 2.5 9.1e-12 44.5 2.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Exo84_C PF16528.5 CEP17153.1 - 0.06 13.2 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Exocyst component 84 C-terminal zf-Nse PF11789.8 CEP17153.1 - 0.13 12.1 0.3 0.36 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 CEP17153.1 - 0.31 11.0 2.0 0.64 9.9 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) M20_dimer PF07687.14 CEP17154.1 - 1.6e-10 40.9 0.0 3.3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PPR_2 PF13041.6 CEP17155.1 - 1.5e-10 41.1 2.9 0.51 10.6 0.0 5.9 6 0 0 6 6 6 4 PPR repeat family PPR_long PF17177.4 CEP17155.1 - 0.00015 21.2 4.3 0.11 11.8 0.0 4.4 5 0 0 5 5 5 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEP17155.1 - 0.00046 20.3 11.4 0.15 12.3 0.0 6.5 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.6 CEP17155.1 - 0.029 14.4 0.7 23 5.1 0.0 4.5 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Matrix PF00661.21 CEP17155.1 - 0.048 12.4 0.0 0.099 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral matrix protein Sec7 PF01369.20 CEP17156.1 - 9.9e-71 237.2 0.0 4.7e-70 235.0 0.0 2.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CEP17156.1 - 1.3e-41 142.2 1.1 1.3e-41 142.2 1.1 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CEP17156.1 - 8.6e-34 115.2 10.9 4e-31 106.7 0.1 6.3 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 CEP17156.1 - 8e-21 74.5 3.1 3.9e-20 72.2 3.1 2.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 CEP17156.1 - 0.00068 17.9 0.0 0.0012 17.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of Mon2 protein Cnd3 PF12719.7 CEP17156.1 - 0.13 11.5 5.5 1.4 8.0 0.1 4.2 3 2 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF1539 PF07560.11 CEP17156.1 - 0.61 10.2 4.3 29 4.8 0.0 4.6 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1539) FAM176 PF14851.6 CEP17156.1 - 5.5 6.7 8.8 18 5.0 4.8 2.6 2 0 0 2 2 2 0 FAM176 family Zn_clus PF00172.18 CEP17157.1 - 0.00046 20.3 11.1 0.0011 19.1 11.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.27 CEP17159.1 - 5.8e-18 65.2 0.2 2.7e-17 63.0 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CEP17159.1 - 1.4e-08 35.3 0.2 3.8e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP17159.1 - 1e-06 29.2 0.0 3.8e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 CEP17159.1 - 0.0014 18.9 1.8 0.0038 17.5 1.8 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.10 CEP17159.1 - 0.051 13.4 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Aspartyl protease ImmE5 PF11480.8 CEP17160.1 - 6.2 7.4 10.7 0.28 11.7 0.3 2.9 3 0 0 3 3 3 0 Colicin-E5 Imm protein Activator_LAG-3 PF11498.8 CEP17161.1 - 0.0047 16.0 18.1 0.0052 15.8 18.1 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Pepsin-I3 PF06394.13 CEP17161.1 - 0.16 12.2 8.2 0.32 11.2 8.2 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Borrelia_P83 PF05262.11 CEP17161.1 - 0.2 10.1 12.4 0.23 9.9 12.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein S-AdoMet_synt_M PF02772.16 CEP17161.1 - 0.24 11.7 5.5 0.14 12.5 3.9 1.4 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain UCH_1 PF13423.6 CEP17161.1 - 0.61 9.6 9.1 0.76 9.3 9.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Spt20 PF12090.8 CEP17161.1 - 1.5 8.4 21.8 1.9 8.0 21.8 1.1 1 0 0 1 1 1 0 Spt20 family ALMT PF11744.8 CEP17161.1 - 4.5 6.0 7.6 4.9 5.9 7.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DDE_3 PF13358.6 CEP17162.1 - 1.9e-11 43.9 0.0 4e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP17162.1 - 2e-09 37.5 0.0 6.1e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 CEP17162.1 - 0.00013 22.0 0.6 0.00031 20.7 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 CEP17162.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_40 PF14493.6 CEP17162.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Ada3 PF10198.9 CEP17163.1 - 8.1e-33 113.4 3.3 8.1e-33 113.4 3.3 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 IL1_propep PF02394.16 CEP17163.1 - 3.5 8.6 8.9 0.15 13.0 0.7 2.7 3 1 0 3 3 3 0 Interleukin-1 propeptide Nup214_FG PF18617.1 CEP17164.1 - 0.58 10.7 3.4 0.38 11.3 1.1 2.0 2 1 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain P21-Arc PF04062.14 CEP17165.1 - 1.4e-52 178.3 0.0 1.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit MNSV_P7B PF06692.11 CEP17165.1 - 0.013 15.5 0.1 0.14 12.2 0.0 2.3 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein SET PF00856.28 CEP17166.1 - 0.0012 19.2 0.1 0.0021 18.5 0.1 1.3 1 1 0 1 1 1 1 SET domain TRPM_tetra PF16519.5 CEP17167.1 - 0.063 13.4 0.6 0.063 13.4 0.6 3.3 4 1 0 4 4 4 0 Tetramerisation domain of TRPM ATG16 PF08614.11 CEP17167.1 - 0.31 11.2 50.2 0.062 13.5 10.2 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 CEP17167.1 - 0.46 10.3 48.4 1.5 8.6 18.9 3.8 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF4686 PF15742.5 CEP17167.1 - 4.2 6.4 54.4 1.2 8.2 49.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Rgp1 PF08737.10 CEP17168.1 - 6.4e-95 318.8 1.8 1.6e-92 310.9 1.8 2.4 1 1 0 1 1 1 1 Rgp1 Tom5 PF10642.9 CEP17168.1 - 3e-12 46.4 2.4 5.5e-12 45.5 2.4 1.5 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Arrestin_C PF02752.22 CEP17168.1 - 0.00077 19.9 1.9 0.2 12.1 0.0 3.6 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP17168.1 - 0.13 12.3 3.5 0.26 11.3 0.0 3.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Sec16 PF12932.7 CEP17169.1 - 0.036 14.6 0.6 0.036 14.6 0.6 4.5 5 1 0 5 5 5 0 Vesicle coat trafficking protein Sec16 mid-region RskA PF10099.9 CEP17169.1 - 5.3 7.3 11.8 0.32 11.3 4.3 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA PH_11 PF15413.6 CEP17169.1 - 8.6 6.8 11.6 1.2 9.6 0.7 4.1 4 1 0 4 4 4 0 Pleckstrin homology domain Pet100 PF09803.9 CEP17170.1 - 6.1e-25 87.5 0.2 7.5e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 Pet100 Snurportin1 PF11538.8 CEP17170.1 - 0.35 11.1 3.8 0.84 9.9 3.8 1.8 1 1 0 1 1 1 0 Snurportin1 PHD PF00628.29 CEP17171.1 - 9.3e-09 35.1 8.5 9.3e-09 35.1 8.5 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CEP17171.1 - 0.11 12.1 3.4 0.24 11.0 3.4 1.6 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 CEP17172.1 - 5.2e-25 87.2 6.7 2.2e-05 25.1 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CEP17172.1 - 8e-24 83.7 1.2 3.7e-23 81.5 0.6 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CEP17172.1 - 5.8e-08 32.9 0.5 0.0057 16.9 0.2 4.3 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ecl1 PF12855.7 CEP17172.1 - 1.1e-05 26.7 5.3 2.8e-05 25.4 5.3 1.7 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CEP17172.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 MYND finger DUF3751 PF12571.8 CEP17172.1 - 0.078 13.0 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Phage tail-collar fibre protein FMO-like PF00743.19 CEP17173.1 - 5.2e-39 134.1 0.0 9.5e-22 77.1 0.1 3.9 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CEP17173.1 - 2.4e-15 56.6 0.0 1.9e-10 40.5 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CEP17173.1 - 9.3e-12 44.8 0.0 1.4e-10 40.9 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CEP17173.1 - 1.7e-08 34.0 0.0 1.7e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CEP17173.1 - 1.5e-06 28.4 0.0 3.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP17173.1 - 7.5e-05 22.5 0.1 0.0071 16.0 0.4 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP17173.1 - 0.00015 21.8 0.1 0.0064 16.5 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CEP17173.1 - 0.00021 20.7 0.1 0.00096 18.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CEP17173.1 - 0.0006 20.2 0.0 0.17 12.3 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.14 CEP17173.1 - 0.0015 17.3 0.1 0.0023 16.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CEP17173.1 - 0.0017 17.6 0.1 0.0054 16.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CEP17173.1 - 0.0023 18.5 3.0 1.1 9.9 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CEP17173.1 - 0.0047 16.3 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.15 CEP17173.1 - 0.0057 16.8 0.1 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.11 CEP17173.1 - 0.0066 16.0 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 CEP17173.1 - 0.0088 16.1 0.0 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CEP17173.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CEP17173.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CEP17173.1 - 0.018 14.4 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CEP17173.1 - 0.025 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEP17173.1 - 0.027 13.9 0.0 0.065 12.6 0.0 1.6 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CEP17173.1 - 0.028 14.0 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glu_dehyd_C PF16912.5 CEP17173.1 - 0.059 12.9 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CEP17173.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 CEP17173.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Phosphorylase PF00343.20 CEP17175.1 - 0 1027.7 0.0 0 1027.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase ESCRT-II PF05871.12 CEP17176.1 - 2.1e-30 105.8 4.6 1.3e-23 83.8 1.6 2.2 1 1 1 2 2 2 2 ESCRT-II complex subunit Creatinase_N_2 PF16189.5 CEP17177.1 - 2.5e-49 167.5 0.0 4.5e-48 163.4 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CEP17177.1 - 6.3e-44 150.2 0.0 9.7e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CEP17177.1 - 5.6e-24 84.0 0.1 8.1e-23 80.3 0.0 2.8 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CEP17177.1 - 6.8e-22 78.5 0.0 2.7e-19 70.1 0.0 2.6 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Sin3a_C PF16879.5 CEP17178.1 - 1.5e-61 208.6 8.2 1.5e-61 208.6 8.2 4.0 6 0 0 6 6 6 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CEP17178.1 - 1.4e-40 137.3 0.2 6.5e-40 135.2 0.1 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 CEP17178.1 - 1.4e-40 137.1 12.0 5.5e-17 61.6 3.0 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat DDE_3 PF13358.6 CEP17179.1 - 4.3e-24 84.9 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_28 PF13518.6 CEP17181.1 - 0.00022 21.3 0.6 0.00035 20.6 0.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP17181.1 - 0.0003 20.5 0.1 0.0006 19.5 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP17181.1 - 0.0024 17.8 0.3 0.004 17.2 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 CEP17181.1 - 0.0029 18.2 0.1 0.0046 17.5 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP17181.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 CEP17181.1 - 0.04 13.9 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 CEP17182.1 - 2.9e-05 23.7 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP17182.1 - 0.0005 20.1 0.2 0.00084 19.4 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP17182.1 - 0.0024 17.8 0.1 0.0053 16.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP17182.1 - 0.005 16.2 0.1 0.0078 15.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 CEP17182.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP17182.1 - 0.034 14.5 0.1 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Transposase Mcp5_PH PF12814.7 CEP17183.1 - 3.3e-37 127.3 0.0 9.6e-37 125.8 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CEP17183.1 - 0.0003 21.3 0.0 0.00081 19.9 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF4179 PF13786.6 CEP17183.1 - 5.1 7.7 7.3 1.9 9.0 0.2 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) SAP PF02037.27 CEP17184.1 - 8e-11 41.4 2.3 8e-11 41.4 2.3 2.3 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 CEP17184.1 - 0.63 9.9 13.3 0.48 10.3 1.1 3.7 3 1 0 3 3 3 0 Tho1/MOS11 C-terminal domain MotY_N PF18393.1 CEP17184.1 - 1.4 9.1 4.2 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 MotY N-terminal domain Pkinase PF00069.25 CEP17185.1 - 4.2e-72 242.7 0.1 1.8e-71 240.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17185.1 - 1.5e-51 175.2 0.0 3.1e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 CEP17185.1 - 1.8e-16 60.2 0.5 5.6e-16 58.7 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain Kinase-like PF14531.6 CEP17185.1 - 3.5e-06 26.5 0.0 0.001 18.5 0.0 2.5 1 1 1 2 2 2 2 Kinase-like C1_1 PF00130.22 CEP17185.1 - 8.5e-05 22.4 10.2 0.00017 21.4 10.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.22 CEP17185.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family CDC24 PF06395.11 CEP17185.1 - 0.016 15.4 0.3 0.046 14.0 0.0 1.9 2 0 0 2 2 2 0 CDC24 Calponin CAMSAP_CH PF11971.8 CEP17185.1 - 0.039 13.8 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain Zn_ribbon_17 PF17120.5 CEP17185.1 - 0.31 10.7 8.0 0.59 9.8 8.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 CEP17185.1 - 0.67 10.1 7.2 2.2 8.5 7.1 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Acetyltransf_1 PF00583.25 CEP17186.1 - 2.2e-14 53.7 0.0 2.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP17186.1 - 3.5e-13 49.6 0.0 5.1e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP17186.1 - 5.4e-10 39.5 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP17186.1 - 6.9e-06 26.3 0.0 9.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP17186.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 CEP17186.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Homeodomain PF00046.29 CEP17187.1 - 7.7e-18 64.1 3.0 7.7e-18 64.1 3.0 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CEP17187.1 - 0.027 14.4 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain DEAD PF00270.29 CEP17188.1 - 3.9e-37 127.7 0.5 6.7e-37 126.9 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17188.1 - 2.8e-23 82.4 0.1 9.5e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP17188.1 - 3e-10 40.4 0.0 3e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CEP17188.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP17188.1 - 0.015 15.6 0.1 0.053 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CEP17188.1 - 0.015 14.6 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 CEP17188.1 - 0.02 15.3 0.1 0.041 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CEP17188.1 - 0.045 13.6 1.6 0.063 13.1 0.1 2.0 2 0 0 2 2 2 0 Helicase zf-C2H2_jaz PF12171.8 CEP17189.1 - 3.7e-07 30.3 4.3 5.6e-07 29.7 4.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SYF2 PF08231.12 CEP17189.1 - 0.026 14.9 3.3 0.049 14.0 3.3 1.5 1 1 0 1 1 1 0 SYF2 splicing factor zf-C2H2_2 PF12756.7 CEP17189.1 - 0.056 13.8 2.6 0.072 13.4 2.6 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Sec66 PF09802.9 CEP17190.1 - 0.015 14.9 0.3 0.015 14.9 0.3 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 AKNA PF12443.8 CEP17190.1 - 0.016 15.8 2.5 0.016 15.8 2.5 4.4 5 1 1 6 6 6 0 AT-hook-containing transcription factor RsbU_N PF08673.10 CEP17190.1 - 0.042 13.9 1.1 0.14 12.2 1.1 1.9 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF948 PF06103.11 CEP17190.1 - 0.66 10.3 16.8 1.7 9.0 0.3 5.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Cupin_4 PF08007.12 CEP17190.1 - 1.1 8.7 12.2 0.17 11.3 0.9 3.7 4 1 0 4 4 4 0 Cupin superfamily protein HSBP1 PF06825.12 CEP17190.1 - 3.2 7.7 6.3 10 6.1 0.2 4.3 5 0 0 5 5 5 0 Heat shock factor binding protein 1 PHM7_cyt PF14703.6 CEP17190.1 - 9.5 6.4 10.4 11 6.2 2.0 2.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RT_RNaseH_2 PF17919.1 CEP17192.1 - 1.9e-22 79.2 0.1 4.3e-22 78.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17192.1 - 6.2e-14 52.2 0.0 1.7e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP17192.1 - 6.8e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP17192.1 - 6.8e-08 32.5 0.4 1.1e-06 28.7 0.1 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CEP17192.1 - 7.1e-05 22.6 0.4 0.0002 21.2 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP17192.1 - 0.016 15.4 0.1 0.065 13.5 0.0 2.2 2 0 0 2 2 2 0 H2C2 zinc finger Peptidase_A17 PF05380.13 CEP17192.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Pao retrotransposon peptidase Retrotrans_gag PF03732.17 CEP17193.1 - 0.00056 20.1 0.2 0.0036 17.5 0.1 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein EF-hand_14 PF17959.1 CEP17193.1 - 0.034 14.5 0.1 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Ebp2 PF05890.12 CEP17197.1 - 3.7e-39 134.9 25.0 5.6e-38 131.0 25.0 2.1 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF3881 PF12997.7 CEP17197.1 - 0.049 12.9 2.1 0.099 11.9 1.5 1.8 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF3332 PF11810.8 CEP17197.1 - 0.18 11.5 0.2 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) MMR_HSR1_Xtn PF16897.5 CEP17198.1 - 1.9e-42 143.6 4.1 3.7e-42 142.6 4.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CEP17198.1 - 2.2e-21 75.7 0.1 3.9e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CEP17198.1 - 9.4e-20 70.8 0.0 2.2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP17198.1 - 6.5e-12 45.3 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEP17198.1 - 0.0012 18.9 0.4 0.28 11.2 0.0 2.5 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 CEP17198.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DinI PF06183.13 CEP17198.1 - 0.013 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 DinI-like family GTP_EFTU PF00009.27 CEP17198.1 - 0.015 14.8 1.5 19 4.7 0.0 3.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.21 CEP17198.1 - 0.016 14.7 0.0 0.045 13.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 CEP17198.1 - 0.016 14.2 0.1 0.032 13.2 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CEP17198.1 - 0.026 14.8 0.3 0.054 13.7 0.3 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CEP17198.1 - 0.045 13.7 0.8 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CEP17198.1 - 0.054 13.7 0.3 0.2 11.9 0.1 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CEP17198.1 - 0.055 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Claudin_2 PF13903.6 CEP17199.1 - 0.00089 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TMIE PF16038.5 CEP17201.1 - 0.069 13.0 1.3 0.17 11.7 1.3 1.6 1 0 0 1 1 1 0 TMIE protein TMEM238 PF15125.6 CEP17201.1 - 1.1 9.6 3.8 1.7 8.9 3.8 1.4 1 1 0 1 1 1 0 TMEM238 protein family NS3_envE PF02723.14 CEP17201.1 - 6.4 6.9 7.0 5.2 7.2 0.4 2.3 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF4192 PF13830.6 CEP17202.1 - 0.078 13.0 0.4 0.12 12.4 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) adh_short PF00106.25 CEP17203.1 - 1.4e-44 151.9 0.9 1.6e-44 151.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP17203.1 - 2.9e-34 118.7 0.1 3.5e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP17203.1 - 5.9e-11 42.6 0.2 7.7e-11 42.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEP17203.1 - 0.0002 20.6 0.1 0.00029 20.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CEP17203.1 - 0.025 14.4 1.3 0.039 13.9 1.3 1.5 1 1 0 1 1 1 0 NAD(P)H-binding ArfGap PF01412.18 CEP17204.1 - 2.1e-35 121.3 0.0 8.5e-35 119.4 0.0 2.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CEP17204.1 - 2e-20 73.5 7.8 5e-20 72.2 7.8 1.5 1 1 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CEP17204.1 - 8.8e-14 51.9 0.4 3e-13 50.2 0.4 1.9 1 0 0 1 1 1 1 PH domain BAR PF03114.18 CEP17204.1 - 0.0022 17.7 6.7 0.0065 16.1 6.7 1.8 1 1 0 1 1 1 1 BAR domain PH_9 PF15410.6 CEP17204.1 - 0.081 13.3 0.4 0.52 10.7 0.4 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain UBX PF00789.20 CEP17205.1 - 3.9e-11 43.0 0.0 1.1e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 UBX domain Pap_E4 PF02711.14 CEP17205.1 - 1.7 9.6 6.9 0.88 10.6 0.3 3.2 4 0 0 4 4 4 0 E4 protein Ribosomal_60s PF00428.19 CEP17206.1 - 5.1e-26 91.1 10.4 6e-26 90.9 10.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MAGE_N PF12440.8 CEP17206.1 - 0.36 11.5 8.8 0.49 11.1 8.8 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal zf-C2H2_4 PF13894.6 CEP17207.1 - 0.0029 18.3 15.1 0.48 11.4 0.7 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP17207.1 - 0.0089 16.4 17.0 0.18 12.3 1.0 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CEP17207.1 - 0.014 15.6 10.8 0.69 10.0 0.1 3.6 3 1 1 4 4 4 0 Aberrant zinc-finger DnaJ_C PF01556.18 CEP17209.1 - 2.5e-28 99.0 0.1 3.6e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP17209.1 - 9.7e-13 48.0 0.6 1.9e-12 47.1 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP17209.1 - 2.7e-05 24.4 9.2 2.7e-05 24.4 9.2 2.1 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CEP17209.1 - 1.4 8.9 12.0 1.9 8.5 0.8 2.9 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein C1_1 PF00130.22 CEP17209.1 - 8.3 6.4 9.3 3.9 7.4 1.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 CEP17209.1 - 8.4 6.9 7.8 2.5 8.5 4.1 2.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Cytochrome_C7 PF14522.6 CEP17209.1 - 8.9 6.4 8.4 0.83 9.7 1.5 2.4 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Ribosomal_S25 PF03297.15 CEP17210.1 - 1.8e-40 137.2 2.2 2.3e-40 136.9 2.2 1.1 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.6 CEP17210.1 - 0.0069 16.4 0.2 0.0081 16.1 0.2 1.2 1 0 0 1 1 1 1 Spermatogenesis family BioT2 MarR_2 PF12802.7 CEP17210.1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 CEP17210.1 - 0.019 14.5 0.4 0.029 13.9 0.4 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIPR PF10592.9 CEP17210.1 - 0.022 14.4 0.4 0.026 14.2 0.4 1.2 1 1 0 1 1 1 0 AIPR protein MoaC PF01967.21 CEP17211.1 - 9.1e-54 181.2 2.3 1e-53 181.1 2.3 1.0 1 0 0 1 1 1 1 MoaC family DUF5515 PF17635.2 CEP17211.1 - 0.1 13.3 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5515) Mob_synth_C PF06463.13 CEP17212.1 - 7.5e-22 77.6 0.1 8.5e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C DUF5069 PF16798.5 CEP17212.1 - 0.14 12.3 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) Radical_SAM PF04055.21 CEP17213.1 - 1.3e-31 110.2 0.0 1.8e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 CEP17213.1 - 3.1e-06 27.5 0.0 5.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Mob_synth_C PF06463.13 CEP17213.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C ThiG PF05690.14 CEP17213.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Fer4_14 PF13394.6 CEP17213.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain AA_permease_2 PF13520.6 CEP17214.1 - 5.4e-56 190.2 55.1 6.7e-56 189.9 55.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP17214.1 - 2.4e-15 56.1 45.3 3.5e-15 55.6 45.3 1.3 1 0 0 1 1 1 1 Amino acid permease DUF2370 PF10176.9 CEP17215.1 - 1.9e-70 237.1 4.8 2.5e-61 207.2 0.1 2.3 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) Mrx7 PF10906.8 CEP17216.1 - 0.00069 19.8 0.1 0.00094 19.4 0.1 1.3 1 0 0 1 1 1 1 MIOREX complex component 7 DUF4364 PF14277.6 CEP17216.1 - 0.052 13.3 0.0 0.052 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF5601 PF18151.1 CEP17216.1 - 0.093 13.1 0.1 16 5.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5601) DEAD PF00270.29 CEP17217.1 - 3.9e-45 153.8 0.1 6.4e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17217.1 - 1.8e-27 95.8 2.1 1e-26 93.5 0.3 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP17217.1 - 2.1e-05 24.6 0.7 6.3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CEP17217.1 - 0.019 14.3 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GTP_cyclohydro2 PF00925.20 CEP17218.1 - 1.6e-63 213.2 0.3 2.4e-63 212.6 0.3 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GN3L_Grn1 PF08701.11 CEP17219.1 - 2e-24 85.5 16.0 2e-24 85.5 16.0 2.5 1 1 2 3 3 3 1 GNL3L/Grn1 putative GTPase Hexokinase_2 PF03727.16 CEP17219.1 - 0.045 13.2 1.4 0.048 13.1 1.4 1.1 1 0 0 1 1 1 0 Hexokinase SF3a60_bindingd PF12108.8 CEP17219.1 - 0.13 12.1 1.2 0.42 10.5 1.2 1.9 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF3138 PF11336.8 CEP17219.1 - 0.68 8.5 8.8 0.84 8.2 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.9 CEP17219.1 - 2.4 8.4 9.2 0.65 10.3 5.5 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Gly-zipper_Omp PF13488.6 CEP17220.1 - 0.0044 17.0 1.3 0.0078 16.2 1.3 1.3 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 CEP17220.1 - 0.0062 16.4 0.5 0.01 15.6 0.5 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 CEP17220.1 - 0.029 14.1 0.4 0.053 13.3 0.4 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Adeno_E3_CR2 PF02439.15 CEP17220.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 WD40 PF00400.32 CEP17221.1 - 6.2e-42 140.8 25.3 1.6e-07 31.8 0.4 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 CEP17221.1 - 1.4e-12 47.1 11.3 0.0043 15.7 0.1 5.7 2 2 3 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 CEP17221.1 - 3e-12 46.2 0.2 6.6e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CEP17221.1 - 8.1e-12 45.3 4.7 0.17 12.2 0.1 6.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CEP17221.1 - 7.8e-09 35.2 0.1 2.2e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ge1_WD40 PF16529.5 CEP17221.1 - 5.8e-05 22.2 3.3 0.11 11.4 0.1 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CEP17221.1 - 0.00024 20.1 7.3 2 7.3 0.0 4.6 2 1 3 5 5 5 3 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 CEP17221.1 - 0.0011 18.3 1.8 0.61 9.3 0.1 3.1 2 1 1 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 CEP17221.1 - 0.0032 16.3 2.8 1.1 7.9 0.0 4.0 2 2 2 4 4 4 2 Nup133 N terminal like F-box_4 PF15966.5 CEP17221.1 - 0.013 15.4 0.1 0.47 10.4 0.0 3.2 3 0 0 3 3 3 0 F-box HARP PF07443.13 CEP17221.1 - 0.17 11.6 0.0 6.4 6.5 0.0 3.3 4 0 0 4 4 4 0 HepA-related protein (HARP) Rio2_N PF09202.11 CEP17222.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Rio2, N-terminal bZIP_1 PF00170.21 CEP17223.1 - 4.2e-11 42.8 4.7 9.9e-11 41.6 3.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP17223.1 - 0.0009 19.3 13.9 0.062 13.4 3.0 2.9 1 1 1 2 2 2 2 Basic region leucine zipper TMF_DNA_bd PF12329.8 CEP17223.1 - 0.046 13.7 3.4 0.18 11.9 3.4 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 CEP17223.1 - 0.21 12.0 0.8 0.6 10.5 0.8 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 CEP17223.1 - 0.96 9.6 12.4 0.031 14.5 3.1 2.8 3 0 0 3 3 3 0 Up-regulated During Septation GalKase_gal_bdg PF10509.9 CEP17224.1 - 8.2e-22 76.5 0.1 1.7e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CEP17224.1 - 3.3e-14 52.9 3.1 8.1e-14 51.6 3.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEP17224.1 - 8.2e-13 48.5 0.0 1.8e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4 PF04545.16 CEP17224.1 - 0.099 12.2 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Aldedh PF00171.22 CEP17225.1 - 2.3e-130 435.2 0.0 3e-130 434.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPEL PF02755.15 CEP17226.1 - 6.1e-16 57.5 12.8 1e-08 34.6 0.4 2.6 3 0 0 3 3 3 2 RPEL repeat Sigma70_r3 PF04539.16 CEP17226.1 - 0.0057 16.7 1.3 0.025 14.7 0.1 2.1 1 1 1 2 2 2 1 Sigma-70 region 3 TPT PF03151.16 CEP17227.1 - 4.7e-16 59.0 22.8 5.9e-16 58.7 22.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Kelch_6 PF13964.6 CEP17228.1 - 0.00041 20.5 0.8 1.5 9.3 0.0 4.2 3 1 1 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CEP17228.1 - 0.002 18.0 0.0 4.9 7.2 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CEP17228.1 - 0.016 14.8 3.6 0.91 9.2 0.0 4.3 4 0 0 4 4 4 0 Kelch motif DUF2207 PF09972.9 CEP17228.1 - 0.069 11.9 1.0 0.23 10.2 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Kelch_2 PF07646.15 CEP17228.1 - 0.15 12.1 0.2 42 4.3 0.0 4.5 6 0 0 6 6 6 0 Kelch motif ASC PF00858.24 CEP17228.1 - 0.18 10.7 0.1 0.18 10.7 0.1 2.7 2 1 0 3 3 3 0 Amiloride-sensitive sodium channel VSP PF03302.13 CEP17228.1 - 0.19 10.6 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein KcnmB2_inactiv PF09303.10 CEP17228.1 - 1.5 8.7 7.2 1 9.2 1.4 3.1 3 0 0 3 3 3 0 KCNMB2, ball and chain domain Phe_tRNA-synt_N PF02912.18 CEP17232.1 - 0.0038 17.1 0.3 24 5.0 0.2 3.1 3 0 0 3 3 3 3 Aminoacyl tRNA synthetase class II, N-terminal domain DUF5638 PF18688.1 CEP17232.1 - 0.0063 16.8 0.1 0.0083 16.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5638) Tnp_22_trimer PF17489.2 CEP17232.1 - 8.7 6.4 7.5 10 6.2 1.5 3.0 2 1 1 3 3 3 0 L1 transposable element trimerization domain CTP_transf_1 PF01148.20 CEP17233.1 - 0.0016 18.2 2.9 0.0026 17.6 2.9 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF5453 PF17534.2 CEP17233.1 - 0.39 10.6 3.3 0.74 9.8 3.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF5326 PF17260.2 CEP17233.1 - 4.7 7.4 7.0 1.1 9.5 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5326) RRM_1 PF00076.22 CEP17234.1 - 5e-18 64.7 0.1 7.1e-18 64.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP17234.1 - 0.00049 19.9 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CEP17234.1 - 0.26 10.9 0.0 0.38 10.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.13 CEP17234.1 - 1.6 7.9 10.4 2.6 7.2 10.4 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 CEP17234.1 - 5.8 5.6 4.1 7.2 5.3 4.1 1.2 1 0 0 1 1 1 0 Presenilin PX PF00787.24 CEP17235.1 - 4.7e-21 74.9 0.1 1.2e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 PX domain FAM92 PF06730.11 CEP17235.1 - 0.0048 16.3 2.4 0.0048 16.3 2.4 1.5 2 0 0 2 2 2 1 FAM92 protein Sec2p PF06428.11 CEP17236.1 - 2.5e-16 59.4 8.9 2.5e-16 59.4 8.9 2.0 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.11 CEP17236.1 - 0.0015 17.5 5.0 0.002 17.1 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF2408 PF10303.9 CEP17236.1 - 0.0036 17.9 1.4 0.0067 17.0 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Filament PF00038.21 CEP17236.1 - 0.0045 16.6 8.5 0.0064 16.1 8.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein Exonuc_VII_L PF02601.15 CEP17236.1 - 0.026 14.1 6.2 0.044 13.3 6.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 CEP17236.1 - 0.058 13.6 12.3 0.092 12.9 12.3 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF3584 PF12128.8 CEP17236.1 - 0.14 9.6 10.2 0.18 9.3 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 CEP17236.1 - 0.41 8.5 8.3 0.54 8.1 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 CEP17236.1 - 0.49 9.8 13.4 0.83 9.1 13.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Laminin_II PF06009.12 CEP17236.1 - 0.64 10.0 6.9 2.1 8.3 3.5 2.3 1 1 1 2 2 2 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 CEP17236.1 - 1.5 9.1 18.7 2.3 8.4 17.0 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Kinesin PF00225.23 CEP17237.1 - 6.6e-94 314.5 6.9 6.6e-94 314.5 6.9 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP17237.1 - 4.1e-17 62.5 9.9 6.7e-17 61.8 1.5 3.7 3 1 0 3 3 3 1 Microtubule binding Surfac_D-trimer PF09006.11 CEP17237.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation MFS_1 PF07690.16 CEP17238.1 - 2.9e-32 112.0 69.7 2e-18 66.4 32.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily RhoGEF PF00621.20 CEP17238.1 - 2.3e-24 86.6 0.1 5.1e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 CEP17238.1 - 9.8e-13 48.3 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 BAR domain MFS_2 PF13347.6 CEP17238.1 - 1.2e-07 30.6 30.7 1.3e-05 24.0 9.0 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein SH3_1 PF00018.28 CEP17238.1 - 3.3e-07 29.8 0.5 7.7e-07 28.6 0.5 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP17238.1 - 1.6e-06 27.9 0.3 3.1e-06 26.9 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP17238.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain zf-C2H2 PF00096.26 CEP17239.1 - 5.4e-06 26.6 9.7 0.0039 17.6 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CEP17239.1 - 9.4e-05 22.6 4.0 0.14 12.5 0.4 2.5 2 1 0 2 2 2 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP17239.1 - 0.0027 18.3 1.1 2.5 8.8 0.1 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CEP17239.1 - 0.0061 16.9 0.9 0.0061 16.9 0.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP17239.1 - 0.2 12.6 7.7 6.2 8.0 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP17239.1 - 0.35 10.9 0.2 0.35 10.9 0.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Transferase PF02458.15 CEP17242.1 - 2.9e-52 177.8 0.0 3.7e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family Lipase_GDSL_2 PF13472.6 CEP17243.1 - 6.1e-25 88.7 0.0 1.5e-24 87.4 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CEP17243.1 - 2.7e-20 73.2 0.1 7e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase SET PF00856.28 CEP17243.1 - 8.8e-19 68.5 1.0 8.8e-19 68.5 1.0 4.3 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 CEP17243.1 - 2.3e-11 44.1 3.1 2.3e-07 31.1 0.3 4.6 3 2 2 5 5 5 2 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.22 CEP17243.1 - 6.5e-08 32.3 0.0 2.6e-06 27.2 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CEP17243.1 - 0.00071 19.2 0.1 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated DUF4871 PF16167.5 CEP17243.1 - 1.5 8.9 3.6 3.7 7.6 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Prok-RING_1 PF14446.6 CEP17244.1 - 0.0084 16.0 1.6 0.0084 16.0 1.6 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 CEP17244.1 - 0.04 13.6 1.6 0.74 9.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CEP17244.1 - 0.075 13.0 7.2 0.1 12.6 4.4 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-CCHC PF00098.23 CEP17244.1 - 0.17 12.0 0.3 0.17 12.0 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-ribbon_3 PF13248.6 CEP17244.1 - 0.2 11.1 4.9 1.4 8.4 1.3 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DUF4611 PF15387.6 CEP17244.1 - 0.21 11.8 1.4 21 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PHD PF00628.29 CEP17244.1 - 0.31 11.0 8.9 4.3 7.3 1.4 3.4 3 1 0 3 3 3 0 PHD-finger DZR PF12773.7 CEP17244.1 - 0.64 10.1 8.0 0.66 10.1 5.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 CEP17244.1 - 1.1 9.0 5.6 2.8 7.8 2.0 2.5 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ribosomal_L32p PF01783.23 CEP17244.1 - 1.9 8.8 15.1 1.1 9.5 9.2 2.8 2 1 1 3 3 3 0 Ribosomal L32p protein family zf-RING-like PF08746.11 CEP17244.1 - 2.1 8.7 18.4 1.6 9.1 8.2 3.1 2 1 1 3 3 3 0 RING-like domain zf-nanos PF05741.13 CEP17244.1 - 5.2 7.4 12.5 8.4 6.7 0.5 3.3 3 0 0 3 3 3 0 Nanos RNA binding domain zf-Di19 PF05605.12 CEP17244.1 - 8.7 6.7 13.7 0.62 10.4 5.3 2.6 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 CEP17244.1 - 8.8 6.4 9.7 8.1 6.5 5.0 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA eIF-5a PF01287.20 CEP17246.1 - 1.5e-27 95.5 0.3 2.6e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RhoGAP PF00620.27 CEP17247.1 - 8.6e-36 123.0 2.3 8.6e-36 123.0 2.3 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CEP17247.1 - 0.31 11.4 3.0 0.73 10.2 0.4 3.0 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_membrane_2 PF06472.15 CEP17248.1 - 2.5e-90 302.5 0.8 3.4e-90 302.1 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CEP17248.1 - 2.2e-16 60.6 0.0 6.6e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CEP17248.1 - 0.00083 18.8 0.1 0.28 10.6 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CEP17248.1 - 0.0033 17.3 0.1 0.0097 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEP17248.1 - 0.0052 17.3 0.1 0.0052 17.3 0.1 2.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CEP17248.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CEP17248.1 - 0.086 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CEP17248.1 - 0.16 11.9 0.8 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain PCI PF01399.27 CEP17249.1 - 2e-09 37.9 1.5 7.5e-09 36.1 0.2 2.1 2 0 0 2 2 2 1 PCI domain Spc7 PF08317.11 CEP17249.1 - 0.007 15.3 0.9 0.012 14.6 0.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein CdvA PF18822.1 CEP17249.1 - 0.018 14.9 0.5 0.031 14.1 0.5 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain CSN7a_helixI PF18392.1 CEP17249.1 - 0.027 14.3 1.2 0.05 13.5 0.9 1.6 1 1 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Snapin_Pallidin PF14712.6 CEP17249.1 - 0.053 14.0 0.4 0.053 14.0 0.4 2.7 2 1 1 3 3 3 0 Snapin/Pallidin DHR10 PF18595.1 CEP17249.1 - 0.097 12.7 3.4 0.18 11.9 3.4 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DivIC PF04977.15 CEP17249.1 - 0.13 12.1 2.2 0.18 11.6 0.9 2.0 2 0 0 2 2 2 0 Septum formation initiator FAD-SLDH PF12318.8 CEP17249.1 - 0.16 12.0 1.5 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase FlaC_arch PF05377.11 CEP17249.1 - 0.62 10.5 3.6 1.5 9.3 0.7 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 CEP17252.1 - 1e-50 172.6 0.0 1.5e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17252.1 - 6.6e-34 117.3 0.0 1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP17252.1 - 0.00029 19.7 0.0 0.00047 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP17252.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1491 PF07372.12 CEP17252.1 - 0.032 14.6 0.0 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) DDE_2 PF02914.15 CEP17252.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase IMPDH PF00478.25 CEP17253.1 - 2.3e-135 451.1 5.2 2.7e-135 450.8 5.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CEP17253.1 - 2.1e-12 47.3 0.0 1.5e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CEP17253.1 - 2.2e-10 40.1 1.4 4.6e-10 39.1 0.8 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CEP17253.1 - 4.7e-06 26.2 9.6 0.017 14.5 7.6 3.0 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CEP17253.1 - 8.1e-05 22.2 2.2 0.0023 17.4 0.2 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CEP17253.1 - 0.00037 19.9 0.1 0.001 18.4 0.1 1.7 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 CEP17253.1 - 0.0072 15.5 1.4 1.7 7.7 0.0 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.19 CEP17253.1 - 0.01 15.3 0.1 0.01 15.3 0.1 1.9 3 0 0 3 3 3 0 KDPG and KHG aldolase G3P_antiterm PF04309.12 CEP17253.1 - 0.041 13.3 0.3 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Perilipin PF03036.16 CEP17254.1 - 4.7e-11 42.4 8.6 1.8e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 Perilipin family FlgN PF05130.12 CEP17254.1 - 0.068 13.7 5.1 0.088 13.3 4.2 1.6 1 1 0 1 1 1 0 FlgN protein Chorismate_synt PF01264.21 CEP17255.1 - 1.3e-138 461.2 0.1 1.5e-138 461.0 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase GatB_N PF02934.15 CEP17256.1 - 8e-105 350.1 0.0 1e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CEP17256.1 - 7.8e-38 129.7 0.1 1.3e-37 129.0 0.1 1.4 1 0 0 1 1 1 1 GatB domain RasGAP PF00616.19 CEP17257.1 - 7.2e-16 58.5 1.8 9.5e-12 45.1 0.0 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CEP17257.1 - 4.5e-13 49.6 1.7 3e-12 46.8 1.7 2.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CEP17257.1 - 0.012 15.3 0.8 0.048 13.4 0.8 2.0 1 0 0 1 1 1 0 CRAL/TRIO domain HEAT PF02985.22 CEP17257.1 - 0.95 9.9 5.5 10 6.7 0.1 5.1 6 0 0 6 6 6 0 HEAT repeat Cnd1_N PF12922.7 CEP17257.1 - 2.6 7.9 8.2 8.3 6.2 1.7 3.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term Macoilin PF09726.9 CEP17257.1 - 2.8 6.4 7.4 4.7 5.7 7.4 1.2 1 0 0 1 1 1 0 Macoilin family XPG_N PF00752.17 CEP17258.1 - 2.5e-15 56.8 0.0 6.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CEP17258.1 - 5.2e-13 49.2 0.0 1.3e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CEP17258.1 - 0.0015 19.1 0.0 0.0091 16.6 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4559 PF15112.6 CEP17258.1 - 0.051 13.3 1.6 0.081 12.6 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ALMT PF11744.8 CEP17259.1 - 4.3e-17 62.1 9.9 2e-13 50.0 4.9 3.0 4 0 0 4 4 4 2 Aluminium activated malate transporter FUSC_2 PF13515.6 CEP17259.1 - 1.8e-15 57.1 9.2 1.8e-15 57.1 9.2 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CEP17259.1 - 4.8e-12 46.2 5.6 2.7e-10 40.5 2.3 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC PF04632.12 CEP17259.1 - 1e-09 37.5 10.5 9.6e-05 21.1 8.1 2.3 2 0 0 2 2 2 2 Fusaric acid resistance protein family CcmD PF04995.14 CEP17259.1 - 1.1 9.4 3.6 0.83 9.8 1.1 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ArAE_1 PF06081.11 CEP17259.1 - 9.1 6.4 14.4 7.4 6.7 3.2 3.0 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 adh_short PF00106.25 CEP17260.1 - 9e-17 61.2 1.2 1.5e-15 57.2 1.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP17260.1 - 2.1e-09 37.3 0.0 7.9e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THOC7 PF05615.13 CEP17261.1 - 1e-18 67.9 9.1 1e-18 67.9 9.1 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 DUF3450 PF11932.8 CEP17261.1 - 0.0069 15.7 5.5 0.0069 15.7 5.5 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) DUF4061 PF13270.6 CEP17261.1 - 0.14 12.5 4.0 0.08 13.3 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) WDCP PF15390.6 CEP17261.1 - 0.16 10.3 5.2 0.19 10.1 5.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Calc_CGRP_IAPP PF00214.19 CEP17263.1 - 0.017 15.5 1.3 0.033 14.5 0.7 1.8 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family MULE PF10551.9 CEP17264.1 - 6.5e-08 32.9 0.1 1.8e-07 31.4 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain MULE PF10551.9 CEP17265.1 - 0.0051 17.2 0.0 0.018 15.5 0.0 2.0 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_4 PF13359.6 CEP17266.1 - 3.9e-17 62.4 0.2 4.4e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 CEP17266.1 - 0.00031 20.4 0.0 0.00067 19.3 0.0 1.6 1 0 0 1 1 1 1 Plant transposon protein HMG-CoA_red PF00368.18 CEP17267.1 - 2.6e-144 480.8 11.0 4.1e-144 480.1 11.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 CEP17267.1 - 4.5e-17 62.3 1.0 4.5e-17 62.3 1.0 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CEP17267.1 - 7.9e-10 37.5 5.8 1.4e-09 36.7 5.8 1.3 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 CEP17267.1 - 0.00038 20.3 0.9 0.0012 18.8 0.9 1.9 1 0 0 1 1 1 1 N-terminal domain with HPIH motif DUF3927 PF13064.6 CEP17267.1 - 1.6 8.7 4.4 0.59 10.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) zf-SNAP50_C PF12251.8 CEP17268.1 - 1.9e-46 158.3 9.4 3e-46 157.6 9.4 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal PPV_E1_N PF00524.18 CEP17268.1 - 0.034 14.6 2.7 2.5 8.5 0.1 2.8 2 0 0 2 2 2 0 E1 Protein, N terminal domain SET PF00856.28 CEP17269.1 - 1.8e-19 70.7 0.0 2.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 CEP17269.1 - 0.00031 21.4 0.1 0.00093 19.9 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding BRE1 PF08647.11 CEP17270.1 - 3.4e-09 36.7 14.2 3.4e-09 36.7 14.2 6.7 6 2 1 7 7 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CEP17270.1 - 1.5e-07 31.1 9.4 3e-07 30.2 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP17270.1 - 1.4e-06 28.0 11.4 2.8e-06 27.1 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP17270.1 - 1.6e-06 28.0 12.7 3.1e-06 27.0 12.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CEP17270.1 - 2.3e-06 27.4 12.0 6e-06 26.0 12.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEP17270.1 - 2.3e-05 24.2 2.2 5.7e-05 22.9 2.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 CEP17270.1 - 3.1e-05 23.9 7.7 7.3e-05 22.7 7.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CEP17270.1 - 0.00011 22.4 11.7 0.00021 21.5 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CEP17270.1 - 0.00011 22.0 7.5 0.00022 21.0 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP17270.1 - 0.0043 17.3 8.0 0.012 15.9 8.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain EzrA PF06160.12 CEP17270.1 - 0.0044 15.3 0.5 0.0044 15.3 0.5 5.1 5 0 0 5 5 5 3 Septation ring formation regulator, EzrA zf-C3HC4_4 PF15227.6 CEP17270.1 - 0.057 13.6 6.4 0.12 12.5 6.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LPD11 PF18824.1 CEP17270.1 - 0.25 11.5 5.7 1.7 8.8 0.7 3.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 zf-RING_4 PF14570.6 CEP17270.1 - 0.39 10.5 9.4 2.3 8.1 9.6 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CEP17270.1 - 1.7 8.6 5.6 4.3 7.3 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.11 CEP17270.1 - 3.7 7.9 16.1 9.1 6.6 0.2 4.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) zf-Nse PF11789.8 CEP17270.1 - 8.9 6.2 7.9 20 5.1 7.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LIDHydrolase PF10230.9 CEP17270.1 - 9 5.8 12.2 0.045 13.3 1.2 2.8 3 1 1 4 4 4 0 Lipid-droplet associated hydrolase Josephin PF02099.17 CEP17271.1 - 1.5e-38 132.4 0.3 3.6e-38 131.2 0.3 1.6 1 0 0 1 1 1 1 Josephin cNMP_binding PF00027.29 CEP17271.1 - 9.1e-35 118.6 0.8 4.9e-17 61.8 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CEP17271.1 - 1.3e-10 40.8 1.2 2.8e-10 39.7 1.2 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2145 PF09916.9 CEP17271.1 - 0.089 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2145) UIM PF02809.20 CEP17271.1 - 0.46 10.5 3.6 0.29 11.1 0.7 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1505 PF07403.11 CEP17272.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Fungus-induced PF10917.8 CEP17272.1 - 0.012 15.9 0.8 0.034 14.5 0.0 1.9 2 0 0 2 2 2 0 Fungus-induced protein Metal_resist PF13801.6 CEP17272.1 - 0.19 12.0 0.2 0.57 10.4 0.0 1.7 2 0 0 2 2 2 0 Heavy-metal resistance Acyltransferase PF01553.21 CEP17273.1 - 2.4e-24 85.5 0.0 3.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase US2 PF02476.15 CEP17273.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.6 2 0 0 2 2 2 0 US2 family DNA_alkylation PF08713.11 CEP17274.1 - 0.042 13.6 0.1 0.077 12.7 0.1 1.6 1 1 0 1 1 1 0 DNA alkylation repair enzyme RBD-FIP PF09457.10 CEP17274.1 - 0.1 12.5 0.6 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 FIP domain Lyase_8 PF02278.18 CEP17275.1 - 1.6e-49 168.7 4.4 2.7e-49 168.0 4.4 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 CEP17275.1 - 2.7e-26 92.2 0.7 4.2e-26 91.6 0.7 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 CEP17275.1 - 3.4e-09 37.1 0.0 8.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_catalyt PF09093.11 CEP17275.1 - 0.0035 16.5 0.2 0.02 14.1 0.1 2.3 3 0 0 3 3 3 1 Lyase, catalytic VIT1 PF01988.19 CEP17276.1 - 2e-69 233.8 0.0 2.4e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 VIT family CRC_subunit PF08624.10 CEP17277.1 - 1.3e-38 132.5 0.0 2.3e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 CEP17277.1 - 1.1e-20 73.3 48.8 4e-09 36.2 14.5 4.3 3 1 1 4 4 4 3 PHD-finger Cytochrom_C PF00034.21 CEP17277.1 - 0.066 14.4 4.2 14 6.9 0.0 3.6 2 0 0 2 2 2 0 Cytochrome c Zn-C2H2_12 PF18112.1 CEP17277.1 - 0.67 10.5 0.0 0.67 10.5 0.0 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain C1_1 PF00130.22 CEP17277.1 - 4.8 7.1 40.8 0.12 12.2 1.3 4.6 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Solute_trans_a PF03619.16 CEP17278.1 - 4.4e-27 95.3 7.6 6.7e-27 94.7 7.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2231 PF09990.9 CEP17278.1 - 0.0057 17.1 0.7 0.016 15.7 0.1 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) Abhydrolase_1 PF00561.20 CEP17279.1 - 1.1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP17279.1 - 1.5e-06 27.7 0.0 3.2e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP17279.1 - 0.00061 20.5 0.0 0.0011 19.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 CEP17279.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Palm_thioest PF02089.15 CEP17279.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase CENP-L PF13092.6 CEP17281.1 - 6.8e-11 42.7 0.1 1.5e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 DUF4269 PF14091.6 CEP17281.1 - 0.0083 16.4 0.5 0.15 12.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4269) GATA PF00320.27 CEP17283.1 - 6.9e-14 51.2 5.6 1.6e-13 50.0 5.6 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.6 CEP17283.1 - 0.22 11.4 2.0 0.44 10.5 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 CEP17283.1 - 0.71 10.0 6.9 0.68 10.0 3.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CEP17283.1 - 1.1 9.5 5.5 0.12 12.5 1.0 1.8 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CEP17283.1 - 1.8 8.6 6.0 2.2 8.3 2.7 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain CLTH PF10607.9 CEP17284.1 - 3.5e-38 130.8 0.4 4.8e-38 130.4 0.4 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CEP17284.1 - 3.5e-10 39.5 0.4 1.3e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 LisH His_biosynth PF00977.21 CEP17285.1 - 3.1e-35 121.7 0.0 3.7e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein HIT PF01230.23 CEP17286.1 - 1.3e-18 67.6 0.1 2.2e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CEP17286.1 - 5.5e-07 30.1 0.2 1.6e-06 28.5 0.1 1.8 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 CEP17286.1 - 0.036 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain MAGE PF01454.19 CEP17287.1 - 4.8e-36 124.5 4.5 6e-32 111.1 1.3 2.2 1 1 1 2 2 2 2 MAGE family Calpain_III PF01067.22 CEP17287.1 - 0.048 13.9 0.8 0.077 13.3 0.8 1.3 1 0 0 1 1 1 0 Calpain large subunit, domain III Inhibitor_I71 PF12628.7 CEP17287.1 - 0.29 11.0 5.9 0.12 12.2 1.0 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor NUDIX PF00293.28 CEP17289.1 - 7.2e-17 61.7 1.4 9.9e-17 61.2 1.4 1.2 1 0 0 1 1 1 1 NUDIX domain ETF_QO PF05187.13 CEP17290.1 - 2.5e-49 165.7 0.1 4.1e-49 165.0 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CEP17290.1 - 4.4e-08 33.1 0.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CEP17290.1 - 8.7e-08 31.7 0.3 0.00054 19.2 1.3 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CEP17290.1 - 4.3e-07 29.4 0.0 0.00037 19.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CEP17290.1 - 5.5e-07 29.7 0.0 2.8e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CEP17290.1 - 1.8e-06 28.4 0.2 0.061 13.9 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP17290.1 - 2.9e-05 23.6 0.0 6.5e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CEP17290.1 - 7.6e-05 21.6 0.3 0.00014 20.7 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 CEP17290.1 - 7.8e-05 22.0 0.1 0.0002 20.7 0.1 1.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP17290.1 - 0.00011 22.3 0.3 0.00027 21.0 0.3 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CEP17290.1 - 0.00029 19.8 0.1 0.0074 15.2 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 CEP17290.1 - 0.00031 20.1 0.2 0.00061 19.1 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 CEP17290.1 - 0.00034 21.1 1.1 0.00092 19.8 1.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 CEP17290.1 - 0.014 14.7 0.3 0.022 14.0 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CEP17290.1 - 0.037 13.1 0.3 0.052 12.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_10 PF13237.6 CEP17290.1 - 0.075 13.2 0.6 0.2 11.8 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 CEP17290.1 - 0.15 12.2 0.6 0.45 10.7 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 CEP17290.1 - 0.27 10.3 0.6 0.39 9.7 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-RING_2 PF13639.6 CEP17291.1 - 8.2e-11 42.1 7.2 1.3e-10 41.4 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP17291.1 - 5.2e-08 32.5 2.3 1.2e-07 31.4 2.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CEP17291.1 - 3e-07 30.4 1.3 3e-07 30.4 1.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CEP17291.1 - 8e-06 26.0 4.6 2.4e-05 24.5 4.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEP17291.1 - 2.3e-05 24.2 5.8 4e-05 23.5 5.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CEP17291.1 - 3.1e-05 23.7 7.6 5.6e-05 22.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP17291.1 - 6.1e-05 22.8 7.2 0.00011 22.0 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.7 CEP17291.1 - 8.9e-05 22.7 2.7 8.9e-05 22.7 2.7 2.8 1 1 1 2 2 1 1 Tropomyosin like zf-C3HC4_3 PF13920.6 CEP17291.1 - 0.00074 19.3 9.0 0.0012 18.6 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CEP17291.1 - 0.0012 18.7 7.7 0.0027 17.5 7.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Fib_alpha PF08702.10 CEP17291.1 - 0.0079 16.4 15.9 0.01 16.0 10.0 2.9 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family PV-1 PF06637.11 CEP17291.1 - 0.0092 14.9 10.7 0.017 14.0 10.7 1.4 1 0 0 1 1 1 1 PV-1 protein (PLVAP) zf-Nse PF11789.8 CEP17291.1 - 0.035 13.9 3.9 0.082 12.7 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CEP17291.1 - 0.047 13.6 10.5 0.08 12.8 10.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CEP17291.1 - 0.28 10.9 4.9 0.45 10.2 4.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SlyX PF04102.12 CEP17291.1 - 0.38 11.4 11.0 11 6.7 1.6 4.3 3 1 1 4 4 4 0 SlyX SAB PF04382.13 CEP17291.1 - 0.49 10.5 4.9 12 6.0 0.2 2.9 2 0 0 2 2 2 0 SAB domain zf-RING_4 PF14570.6 CEP17291.1 - 0.63 9.9 4.7 1.2 9.0 4.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CEP17291.1 - 0.85 9.7 3.8 1.7 8.7 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4474 PF14751.6 CEP17291.1 - 1.1 8.7 3.7 1.8 7.9 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4474) ERM PF00769.19 CEP17291.1 - 2 8.2 24.9 22 4.8 23.9 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Usp PF00582.26 CEP17291.1 - 2.3 8.7 4.6 1.3 9.5 1.8 2.0 2 1 0 2 2 2 0 Universal stress protein family PRKG1_interact PF15898.5 CEP17291.1 - 2.8 8.9 28.4 5.5 7.9 10.9 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain SKA2 PF16740.5 CEP17291.1 - 4.3 7.2 20.7 0.74 9.6 9.6 3.6 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 YtxH PF12732.7 CEP17291.1 - 8.3 7.0 8.7 27 5.4 3.2 3.1 2 2 1 3 3 3 0 YtxH-like protein HIP1_clath_bdg PF16515.5 CEP17291.1 - 8.3 7.1 26.1 3.5 8.3 10.8 3.9 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med10 PF09748.9 CEP17292.1 - 0.027 14.4 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF3294 PF07957.11 CEP17292.1 - 0.27 10.9 2.7 0.13 12.0 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) MCC-bdg_PDZ PF10506.9 CEP17293.1 - 0.042 13.9 0.4 0.042 13.9 0.4 4.9 5 1 1 6 6 6 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FlaC_arch PF05377.11 CEP17293.1 - 6.7 7.2 14.8 30 5.1 4.5 5.0 3 3 1 4 4 4 0 Flagella accessory protein C (FlaC) zf-RING_2 PF13639.6 CEP17294.1 - 1.4e-06 28.5 8.5 3.4e-06 27.3 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CEP17294.1 - 0.0004 20.6 4.8 0.0012 19.0 4.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CEP17294.1 - 0.001 18.9 7.2 0.0037 17.1 7.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP17294.1 - 0.0032 17.5 7.3 0.0032 17.5 7.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CEP17294.1 - 0.014 15.1 8.3 0.014 15.1 8.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 CEP17294.1 - 0.059 13.3 12.3 0.14 12.2 12.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain NPV_P10 PF05531.12 CEP17294.1 - 2 8.9 7.5 27 5.3 1.7 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_3 PF13920.6 CEP17294.1 - 4.8 7.1 10.7 11 6.0 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP17294.1 - 5.1 7.1 12.1 0.32 10.9 6.3 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LrgB PF04172.16 CEP17295.1 - 1.8e-37 128.9 9.7 1.8e-37 128.9 9.7 1.9 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.14 CEP17295.1 - 4.1e-09 36.3 5.7 4.1e-09 36.3 5.7 2.6 2 0 0 2 2 2 1 LrgA family DUF4521 PF15021.6 CEP17295.1 - 0.043 13.7 0.5 0.061 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) PSS PF03034.15 CEP17295.1 - 0.87 9.3 5.2 18 5.0 5.1 2.4 1 1 1 2 2 2 0 Phosphatidyl serine synthase CotH PF08757.11 CEP17296.1 - 3.8e-26 92.4 5.1 5.8e-26 91.8 5.1 1.3 1 0 0 1 1 1 1 CotH kinase protein DUF1325 PF07039.11 CEP17297.1 - 1.1e-38 132.3 0.7 1.6e-38 131.7 0.7 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CEP17297.1 - 0.0014 18.4 1.3 0.0032 17.3 0.3 2.0 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 CEP17297.1 - 0.011 15.5 0.2 0.16 11.8 0.0 2.6 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain PCB_OB PF17092.5 CEP17297.1 - 0.024 15.4 0.1 12 6.7 0.0 2.3 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain TUDOR PF00567.24 CEP17297.1 - 0.027 14.5 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Tudor domain FAM193_C PF15914.5 CEP17297.1 - 0.039 13.7 0.9 0.057 13.2 0.0 1.7 2 0 0 2 2 2 0 FAM193 family C-terminal TUDOR_5 PF18359.1 CEP17297.1 - 0.041 13.6 0.5 0.3 10.8 0.2 2.5 2 1 1 3 3 3 0 Histone methyltransferase Tudor domain 1 RabGAP-TBC PF00566.18 CEP17298.1 - 1.3e-42 145.9 1.1 2.5e-42 145.0 1.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3246 PF11596.8 CEP17298.1 - 0.076 12.4 2.6 0.12 11.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDO_I PF05995.12 CEP17299.1 - 1.3e-33 115.7 0.8 1.4e-23 83.1 0.3 2.9 2 1 0 2 2 2 2 Cysteine dioxygenase type I PCO_ADO PF07847.12 CEP17299.1 - 1.9e-05 24.2 0.3 4.6e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 PCO_ADO SH3_1 PF00018.28 CEP17300.1 - 6.7e-42 140.9 8.5 2e-14 52.9 0.4 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 CEP17300.1 - 1.8e-39 133.3 10.5 6.4e-14 51.5 0.5 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 CEP17300.1 - 1.9e-32 110.9 0.1 4.3e-32 109.7 0.1 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CEP17300.1 - 6e-32 109.1 0.3 4.7e-10 39.0 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain zf-RING_2 PF13639.6 CEP17300.1 - 8e-10 38.9 7.2 1.5e-09 38.0 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CEP17300.1 - 1.9e-07 30.7 0.8 4.5e-07 29.5 0.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CEP17300.1 - 3e-06 27.0 5.2 5.2e-06 26.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.11 CEP17300.1 - 3.5e-06 27.2 3.9 0.17 12.2 0.0 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain zf-C3HC4 PF00097.25 CEP17300.1 - 5.8e-06 26.1 7.0 1.1e-05 25.1 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP17300.1 - 9.6e-06 25.3 7.8 1.9e-05 24.4 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CEP17300.1 - 2.1e-05 24.4 6.1 3.8e-05 23.6 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP17300.1 - 2.2e-05 24.4 5.1 5.6e-05 23.1 5.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger SH3_10 PF17902.1 CEP17300.1 - 0.0012 18.9 0.3 2 8.6 0.1 3.9 4 0 0 4 4 4 1 SH3 domain Prok-RING_4 PF14447.6 CEP17300.1 - 0.0026 17.6 5.2 0.0058 16.5 5.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CEP17300.1 - 0.0047 17.2 5.7 0.0088 16.3 4.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Rtf2 PF04641.12 CEP17300.1 - 0.0063 15.9 2.1 0.0063 15.9 2.1 4.6 4 0 0 4 4 4 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 CEP17300.1 - 0.025 14.7 7.8 0.056 13.6 7.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CEP17300.1 - 0.068 13.0 2.4 0.16 11.8 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CEP17300.1 - 0.19 11.8 1.7 0.5 10.5 1.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger hSH3 PF14603.6 CEP17300.1 - 0.45 11.0 4.6 7.2 7.1 0.0 4.4 5 0 0 5 5 5 0 Helically-extended SH3 domain zf-RING_4 PF14570.6 CEP17300.1 - 4.1 7.3 5.2 8.8 6.2 5.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nkap_C PF06047.11 CEP17301.1 - 1.6e-45 153.4 3.3 1.6e-45 153.4 3.3 2.2 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain CENP-I PF07778.11 CEP17301.1 - 6 5.5 8.9 9.2 4.8 0.1 2.2 2 0 0 2 2 2 0 Mis6 Ribosomal_L37 PF08561.10 CEP17302.1 - 1.1e-21 77.5 6.6 3.8e-20 72.6 2.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 PPV_E1_N PF00524.18 CEP17302.1 - 0.03 14.8 0.3 0.044 14.2 0.2 1.3 1 1 0 1 1 1 0 E1 Protein, N terminal domain STAR_dimer PF16544.5 CEP17302.1 - 1.7 8.2 4.2 0.84 9.3 0.1 2.5 3 0 0 3 3 3 0 Homodimerisation region of STAR domain protein Ras PF00071.22 CEP17303.1 - 1.3e-49 167.9 0.0 2.6e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP17303.1 - 1.8e-22 79.8 1.9 6.9e-22 77.9 0.0 2.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Abhydrolase_3 PF07859.13 CEP17303.1 - 2.3e-13 50.5 0.0 6.1e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CEP17303.1 - 5.1e-08 32.5 0.4 2e-07 30.5 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 COesterase PF00135.28 CEP17303.1 - 6e-08 32.0 0.0 3.5e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CEP17303.1 - 6.8e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family RNase_P_pop3 PF08228.11 CEP17303.1 - 1.2e-07 31.9 0.1 2.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 Arf PF00025.21 CEP17303.1 - 5.7e-07 29.2 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Abhydrolase_6 PF12697.7 CEP17303.1 - 0.00028 21.6 0.0 0.00075 20.2 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family RsgA_GTPase PF03193.16 CEP17303.1 - 0.00047 20.1 0.4 0.37 10.7 0.0 3.5 4 0 0 4 4 4 1 RsgA GTPase MDM1 PF15501.6 CEP17303.1 - 0.0015 17.8 3.3 0.002 17.4 3.3 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 Chlorophyllase2 PF12740.7 CEP17303.1 - 0.0022 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 CEP17303.1 - 0.0037 16.9 0.0 0.0037 16.9 0.0 2.0 2 0 0 2 2 1 1 Lipid-droplet associated hydrolase ABC_tran PF00005.27 CEP17303.1 - 0.016 15.7 0.7 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Abhydrolase_1 PF00561.20 CEP17303.1 - 0.017 14.8 0.8 0.062 12.9 0.4 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CEP17303.1 - 0.036 13.9 0.0 0.036 13.9 0.0 3.1 3 1 1 4 4 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 CEP17303.1 - 0.041 13.6 0.1 0.041 13.6 0.1 1.8 2 0 0 2 2 1 0 PGAP1-like protein DUF2974 PF11187.8 CEP17303.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2974) DUF1749 PF08538.10 CEP17303.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Pannexin_like PF12534.8 CEP17303.1 - 0.071 12.2 4.9 0.12 11.4 4.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_23 PF13476.6 CEP17303.1 - 0.094 13.2 8.9 2.2 8.8 4.0 2.5 2 0 0 2 2 2 0 AAA domain Esterase PF00756.20 CEP17303.1 - 0.14 11.8 1.7 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Putative esterase Presenilin PF01080.17 CEP17303.1 - 0.15 10.8 1.6 0.21 10.3 1.6 1.2 1 0 0 1 1 1 0 Presenilin AAA_24 PF13479.6 CEP17303.1 - 0.27 11.0 4.0 0.54 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain GvpL_GvpF PF06386.11 CEP17303.1 - 1.1 9.1 4.5 2 8.3 3.1 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TERB2 PF15101.6 CEP17303.1 - 1.3 9.0 7.7 2.7 8.0 7.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ALMT PF11744.8 CEP17303.1 - 3.8 6.2 5.8 3.5 6.4 4.3 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Spt20 PF12090.8 CEP17303.1 - 5.2 6.6 21.7 10 5.7 21.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF2681 PF10883.8 CEP17303.1 - 5.4 7.5 16.3 13 6.3 16.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3453 PF11935.8 CEP17304.1 - 1.8e-30 106.3 13.0 2.7e-30 105.7 5.5 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3453) HEAT PF02985.22 CEP17304.1 - 0.00022 21.2 0.7 1.1 9.6 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CEP17304.1 - 0.0035 17.7 0.0 5 7.6 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats PEHE PF15275.6 CEP17304.1 - 0.0037 17.9 3.0 0.047 14.3 0.0 2.8 2 0 0 2 2 2 1 PEHE domain V-ATPase_H_C PF11698.8 CEP17304.1 - 0.0037 17.4 3.6 10 6.2 0.0 4.4 4 0 0 4 4 4 1 V-ATPase subunit H Arm PF00514.23 CEP17304.1 - 0.019 15.0 0.6 1.8 8.7 0.1 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF3388 PF11868.8 CEP17304.1 - 0.04 13.2 1.7 0.41 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3388) PIF1 PF05970.14 CEP17305.1 - 6.9e-08 32.0 0.1 1.4e-07 31.0 0.2 1.5 2 0 0 2 2 2 1 PIF1-like helicase DDE_3 PF13358.6 CEP17307.1 - 4.1e-26 91.5 0.0 7.2e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.6 CEP17307.1 - 1.9e-05 24.7 1.4 5e-05 23.3 1.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CEP17307.1 - 0.00052 20.6 0.4 0.0025 18.4 0.1 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP17307.1 - 0.00076 19.4 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 CEP17307.1 - 0.0034 16.8 0.0 0.0078 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 FeoC PF09012.10 CEP17307.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_23 PF13384.6 CEP17307.1 - 0.14 12.0 0.2 0.39 10.6 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain PH PF00169.29 CEP17308.1 - 2e-19 70.0 1.4 6.4e-19 68.4 1.4 1.9 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 CEP17308.1 - 5.1e-17 61.7 0.1 1.2e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CEP17308.1 - 2.6e-14 52.8 0.0 5.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CEP17308.1 - 3.2e-14 53.1 0.3 9.3e-14 51.6 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 CEP17308.1 - 2.2e-13 49.6 0.2 5.7e-13 48.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP17308.1 - 3.2e-09 36.3 0.0 7.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 CEP17308.1 - 2.6e-08 34.0 0.0 8.6e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_11 PF15413.6 CEP17308.1 - 2.1e-07 31.3 5.9 4.1e-05 24.0 5.9 3.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CEP17308.1 - 0.0023 18.2 0.1 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_4 PF18017.1 CEP17308.1 - 0.0032 17.4 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 CEP17308.1 - 0.12 12.6 0.4 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 Ste50p, sterile alpha motif ENTH PF01417.20 CEP17309.1 - 6.4e-44 149.0 0.8 1.5e-43 147.8 0.6 1.8 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 CEP17309.1 - 4.3e-05 22.6 0.1 6.7e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 ANTH domain Biopterin_H PF00351.21 CEP17309.1 - 0.095 11.7 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Mod_r PF07200.13 CEP17310.1 - 2.1e-32 112.3 7.4 2.1e-32 112.3 7.4 8.3 6 2 1 7 7 7 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 CEP17310.1 - 0.0068 16.3 0.3 0.024 14.5 0.3 2.0 1 0 0 1 1 1 1 UEV domain TspO_MBR PF03073.15 CEP17310.1 - 0.25 11.4 0.1 0.44 10.6 0.1 1.3 1 0 0 1 1 1 0 TspO/MBR family DDE_3 PF13358.6 CEP17312.1 - 1.9e-24 86.1 0.0 5.7e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 CEP17312.1 - 2.2e-06 28.2 0.0 7e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 CEP17312.1 - 0.0094 15.7 2.2 0.2 11.5 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CEP17312.1 - 0.024 14.8 5.5 0.1 12.7 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Receptor_2B4 PF11465.8 CEP17312.1 - 0.14 12.4 0.5 0.51 10.5 0.1 2.1 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Pkinase PF00069.25 CEP17314.1 - 1.5e-78 263.8 0.0 1.9e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17314.1 - 5.7e-36 124.1 0.0 7.6e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP17314.1 - 7.5e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP17314.1 - 0.00018 20.4 0.0 0.00062 18.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CEP17314.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CEP17314.1 - 0.011 15.6 0.0 0.059 13.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 CEP17314.1 - 0.039 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 CEP17314.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.6 CEP17315.1 - 1.8e-19 70.2 0.0 4.3e-19 69.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP17315.1 - 1.4e-18 67.3 0.0 2.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP17315.1 - 2.3e-13 50.6 0.0 4.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP17315.1 - 1.5e-11 44.9 0.0 2.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP17315.1 - 6.4e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP17315.1 - 6.2e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CEP17315.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 CEP17315.1 - 0.00079 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CEP17315.1 - 0.0025 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEP17315.1 - 0.013 15.1 0.1 0.034 13.7 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 CEP17315.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 CEP17315.1 - 0.037 14.0 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CEP17315.1 - 0.099 11.7 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase DDE_3 PF13358.6 CEP17317.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.24 CEP17318.1 - 6.8e-101 338.3 19.9 9.1e-101 337.9 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP17318.1 - 3.2e-28 98.7 26.4 1.5e-22 80.0 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CEP17318.1 - 0.037 12.3 13.6 0.077 11.3 0.8 3.4 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_9_N PF15420.6 CEP17318.1 - 0.49 10.4 4.3 0.86 9.6 4.0 1.6 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Cytochrom_B_C PF00032.17 CEP17318.1 - 1.6 9.1 7.0 1.4 9.2 0.1 3.2 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD VIT1 PF01988.19 CEP17318.1 - 4 7.3 11.6 2.4 8.0 0.4 3.2 3 0 0 3 3 3 0 VIT family FKBP_C PF00254.28 CEP17319.1 - 1.8e-33 114.7 0.0 5.5e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase AhpC-TSA PF00578.21 CEP17321.1 - 2.5e-31 108.1 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP17321.1 - 1.6e-13 50.6 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CEP17321.1 - 2.5e-10 40.0 0.0 4.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box PF00646.33 CEP17322.1 - 0.037 13.9 0.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 F-box domain zf-RVT PF13966.6 CEP17323.1 - 7.8e-08 32.9 0.7 1.4e-07 32.1 0.7 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PH_9 PF15410.6 CEP17324.1 - 1.3e-08 35.3 0.0 3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP17324.1 - 2e-05 25.0 0.0 5.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 PH domain Ribosomal_L36e PF01158.18 CEP17325.1 - 3.2e-38 129.9 3.3 3.5e-38 129.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.12 CEP17325.1 - 0.0046 16.8 0.1 0.0058 16.5 0.1 1.1 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.7 CEP17325.1 - 0.051 13.1 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction HAD PF12710.7 CEP17326.1 - 2.3e-08 34.7 0.0 5e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP17326.1 - 0.016 14.9 0.0 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CEP17326.1 - 0.026 14.1 0.0 0.062 12.8 0.0 1.7 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 CEP17326.1 - 0.096 12.1 0.1 19 4.6 0.0 3.1 2 1 0 2 2 2 0 Putative Phosphatase MIT PF04212.18 CEP17327.1 - 7e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FAM76 PF16046.5 CEP17327.1 - 0.0073 15.7 2.3 0.0092 15.4 2.3 1.1 1 0 0 1 1 1 1 FAM76 protein Spermine_synth PF01564.17 CEP17328.1 - 6.5e-67 224.6 0.0 1.2e-66 223.7 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CEP17328.1 - 9.9e-24 83.0 0.2 2e-23 82.0 0.2 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CEP17328.1 - 0.00052 20.7 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 CEP17328.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 CEP17328.1 - 0.067 13.9 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L28e PF01778.17 CEP17329.1 - 9.3e-34 116.6 5.7 1.2e-33 116.2 5.7 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2500 PF10694.9 CEP17329.1 - 0.4 11.2 2.8 0.5 10.9 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) RRM_1 PF00076.22 CEP17330.1 - 0.0013 18.5 0.0 3.1 7.7 0.0 3.5 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pan3_PK PF18101.1 CEP17331.1 - 5.1e-32 110.7 0.0 8.5e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CEP17331.1 - 2.4e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17331.1 - 0.057 12.7 0.0 0.26 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein tyrosine kinase Amidohydro_1 PF01979.20 CEP17332.1 - 1.1e-19 70.9 0.0 3.1e-15 56.3 0.0 3.5 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 CEP17332.1 - 1.5e-18 67.6 0.8 3.7e-13 49.8 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Spidroin_N PF16763.5 CEP17334.1 - 0.19 11.8 3.1 0.44 10.6 3.1 1.6 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term IF4E PF01652.18 CEP17335.1 - 4.9e-39 133.7 1.6 6.6e-39 133.2 1.6 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SRP54_N PF02881.19 CEP17335.1 - 0.083 13.1 0.2 13 6.1 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Oxysterol_BP PF01237.18 CEP17336.1 - 3.6e-82 276.2 2.7 3.2e-80 269.8 2.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein ADH_N PF08240.12 CEP17337.1 - 1e-17 63.9 2.3 1.8e-17 63.2 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP17337.1 - 6.5e-13 48.8 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP17337.1 - 0.0037 18.3 0.0 0.0058 17.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CEP17337.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 CEP17338.1 - 5.5e-37 125.4 0.0 1.2e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP17338.1 - 7.1e-07 28.9 0.1 0.15 11.7 0.0 3.2 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP17338.1 - 1.7e-05 24.6 0.9 0.00052 19.8 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CEP17338.1 - 6.8e-05 22.8 0.0 0.46 10.5 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CEP17338.1 - 6.8e-05 22.9 0.1 0.64 10.1 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 CEP17338.1 - 0.0033 17.4 0.1 0.81 9.8 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif NosL PF05573.12 CEP17338.1 - 0.12 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 NosL Zn_clus PF00172.18 CEP17339.1 - 0.0016 18.5 11.7 0.0037 17.4 11.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 CEP17339.1 - 0.066 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold Med13_C PF06333.12 CEP17339.1 - 0.36 10.0 8.5 0.85 8.8 8.5 1.6 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rib_5-P_isom_A PF06026.14 CEP17340.1 - 5.6e-62 208.4 0.0 6.9e-62 208.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CEP17340.1 - 0.0073 16.3 0.2 0.95 9.4 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 CEP17340.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Linker_histone PF00538.19 CEP17341.1 - 2.7e-26 91.7 0.4 2.7e-26 91.7 0.4 2.1 2 1 0 2 2 2 1 linker histone H1 and H5 family SLC12 PF03522.15 CEP17341.1 - 0.15 11.0 6.2 0.21 10.6 6.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Ribosomal_S5 PF00333.20 CEP17342.1 - 1.9e-28 98.2 0.8 3.8e-28 97.2 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CEP17342.1 - 3.1e-24 84.2 0.1 5.3e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF5320 PF17253.2 CEP17342.1 - 0.13 13.4 2.6 0.21 12.7 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 CEP17342.1 - 6.4 7.4 7.6 13 6.4 7.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Carn_acyltransf PF00755.20 CEP17343.1 - 2.1e-209 697.0 0.1 2.4e-209 696.8 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Phage_T4_Gp30_7 PF06919.11 CEP17343.1 - 0.056 13.6 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage Gp30.7 protein Mito_carr PF00153.27 CEP17344.1 - 5.2e-67 221.8 3.0 3.6e-22 78.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_TAC_12 PF12363.8 CEP17345.1 - 0.024 15.1 0.4 0.05 14.0 0.4 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Peptidase_C65 PF10275.9 CEP17347.1 - 0.00086 18.8 0.4 0.0017 17.9 0.4 1.5 1 0 0 1 1 1 1 Peptidase C65 Otubain HLH PF00010.26 CEP17349.1 - 2.4e-19 69.0 1.1 3.7e-19 68.4 0.1 1.8 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain AAA_13 PF13166.6 CEP17349.1 - 0.0055 15.4 2.1 0.0075 15.0 2.1 1.1 1 0 0 1 1 1 1 AAA domain DUF4085 PF13315.6 CEP17349.1 - 0.0055 16.4 0.8 0.0081 15.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) DUF1978 PF09321.10 CEP17349.1 - 0.22 10.8 6.1 0.29 10.4 4.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1978) Hairpins PF04877.12 CEP17349.1 - 0.29 10.7 1.7 3.6 7.1 0.3 2.0 2 0 0 2 2 2 0 HrpZ ZapB PF06005.12 CEP17349.1 - 0.84 10.1 11.6 1.7 9.1 0.2 2.3 2 0 0 2 2 2 0 Cell division protein ZapB zf-RVT PF13966.6 CEP17350.1 - 6.5e-06 26.8 1.1 1.9e-05 25.3 1.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Transposase_31 PF04754.12 CEP17351.1 - 0.08 12.5 0.1 0.35 10.5 0.1 1.9 1 1 0 1 1 1 0 Putative transposase, YhgA-like Gelsolin PF00626.22 CEP17352.1 - 1e-38 131.1 0.1 5e-14 52.0 0.1 3.4 3 0 0 3 3 3 3 Gelsolin repeat DUF1779 PF08680.10 CEP17352.1 - 0.012 15.8 0.3 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 TATA-box binding DUF1752 PF08550.10 CEP17353.1 - 1.8e-10 40.4 0.3 3.9e-10 39.4 0.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) YL1 PF05764.13 CEP17353.1 - 0.0037 17.4 11.5 0.0054 16.9 11.5 1.2 1 0 0 1 1 1 1 YL1 nuclear protein ABC_tran_Xtn PF12848.7 CEP17353.1 - 0.0053 16.8 0.4 0.012 15.6 0.4 1.6 1 0 0 1 1 1 1 ABC transporter FANCM-MHF_bd PF16783.5 CEP17353.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.8 4 0 0 4 4 4 0 FANCM to MHF binding domain SDA1 PF05285.12 CEP17353.1 - 0.16 11.4 11.9 0.23 10.8 11.9 1.2 1 0 0 1 1 1 0 SDA1 KDZ PF18758.1 CEP17353.1 - 0.9 9.1 5.5 1.9 8.0 5.5 1.5 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Macoilin PF09726.9 CEP17353.1 - 0.95 7.9 10.8 1.2 7.6 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Cyclin PF08613.11 CEP17354.1 - 3e-12 47.2 0.0 3e-12 47.2 0.0 4.6 5 2 0 5 5 5 1 Cyclin Cyclin_N PF00134.23 CEP17354.1 - 2.3e-05 24.1 0.1 2.3e-05 24.1 0.1 4.1 5 0 0 5 5 5 1 Cyclin, N-terminal domain Exonuc_VII_L PF02601.15 CEP17354.1 - 0.0017 18.0 7.0 0.0017 18.0 7.0 3.6 3 1 0 3 3 3 1 Exonuclease VII, large subunit eIF-3_zeta PF05091.12 CEP17354.1 - 8.6 5.2 55.4 1.7 7.5 12.4 3.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDP-OH_P_transf PF01066.21 CEP17355.1 - 4.8e-18 65.7 0.1 4.8e-18 65.7 0.1 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CorA PF01544.18 CEP17357.1 - 0.065 12.5 2.0 0.08 12.2 2.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DDE_3 PF13358.6 CEP17359.1 - 4.4e-19 68.7 0.0 1.1e-14 54.4 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Retrotrans_gag PF03732.17 CEP17360.1 - 0.0025 18.0 0.1 0.017 15.4 0.0 2.3 2 1 0 2 2 2 1 Retrotransposon gag protein Cytochrom_C550 PF14495.6 CEP17360.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain 2H-phosphodiest PF08975.10 CEP17361.1 - 0.15 12.0 0.1 9.4 6.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1868) Ribosomal_S6 PF01250.17 CEP17362.1 - 1.3e-24 86.2 0.0 1.5e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 HTH_Tnp_Tc3_2 PF01498.18 CEP17364.1 - 6.6e-08 32.7 0.1 1.1e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Transposase RabGAP-TBC PF00566.18 CEP17365.1 - 2.5e-29 102.5 9.7 2.4e-25 89.4 0.2 3.6 3 1 0 3 3 3 2 Rab-GTPase-TBC domain DUF2141 PF09912.9 CEP17366.1 - 0.0042 17.0 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) Wzt_C PF14524.6 CEP17366.1 - 0.086 12.9 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain TPR_2 PF07719.17 CEP17367.1 - 1.4e-08 34.2 0.0 0.008 16.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP17367.1 - 6e-08 32.2 0.0 0.00076 19.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP17367.1 - 1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CEP17367.1 - 4e-06 26.4 0.0 0.00011 21.8 0.0 2.3 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.6 CEP17367.1 - 4.8e-05 23.8 0.1 0.27 12.2 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17367.1 - 0.00022 21.2 0.0 0.016 15.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17367.1 - 0.025 14.8 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Retrotrans_gag PF03732.17 CEP17368.1 - 0.00077 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CEP17368.1 - 0.00087 19.3 0.8 0.00087 19.3 0.8 1.7 2 0 0 2 2 2 1 Zinc knuckle B PF02216.16 CEP17368.1 - 0.14 12.1 0.1 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 B domain Histone PF00125.24 CEP17369.1 - 2.5e-22 79.6 0.4 3.2e-22 79.3 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEP17369.1 - 6.2e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CEP17369.1 - 0.00019 21.8 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CEP17369.1 - 0.017 15.3 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CEP17370.1 - 1.1e-20 73.0 1.2 2e-20 72.2 1.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CEP17370.1 - 1e-16 61.5 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CEP17370.1 - 2e-05 24.8 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAM176 PF14851.6 CEP17371.1 - 1 9.0 5.2 1.5 8.5 5.2 1.3 1 0 0 1 1 1 0 FAM176 family CENP-T_C PF15511.6 CEP17372.1 - 9e-09 35.4 0.1 1.1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CEP17372.1 - 3.8e-05 23.8 0.1 5.4e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CEP17372.1 - 5.4e-05 23.6 0.1 6.3e-05 23.3 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP17372.1 - 8.9e-05 22.8 0.1 0.00012 22.4 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CEP17372.1 - 0.00022 21.5 0.1 0.00042 20.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP17372.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP17372.1 - 0.08 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CEP17372.1 - 0.15 12.6 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CEP17373.1 - 1.3e-52 177.6 2.7 1.4e-52 177.5 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CEP17373.1 - 2.3e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEP17373.1 - 2.7e-05 24.3 0.4 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CEP17373.1 - 6.1e-05 23.6 1.1 7.3e-05 23.4 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CEP17373.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CEP17373.1 - 0.057 13.5 0.1 0.094 12.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CEP17373.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2462 PF09495.10 CEP17374.1 - 3.9e-18 65.9 13.5 3.9e-18 65.9 13.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Fibrillarin PF01269.17 CEP17375.1 - 5.9e-108 359.2 0.0 7.4e-108 358.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CEP17375.1 - 4.7e-05 23.2 0.0 7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CEP17375.1 - 0.019 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CEP17375.1 - 0.023 14.3 0.0 0.068 12.8 0.0 1.6 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 CEP17375.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) INTS2 PF14750.6 CEP17377.1 - 9.8e-76 255.2 11.4 2.9e-75 253.6 11.4 1.6 1 1 0 1 1 1 1 Integrator complex subunit 2 DUF1977 PF09320.11 CEP17378.1 - 3e-24 85.3 0.3 3e-24 85.3 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CEP17378.1 - 4.8e-23 81.1 1.2 1.2e-22 79.8 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CEP17378.1 - 0.025 14.7 0.1 0.23 11.7 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC_CDC26 PF10471.9 CEP17378.1 - 0.11 13.3 0.5 0.11 13.3 0.5 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 PGM_PMM_I PF02878.16 CEP17379.1 - 1.4e-18 67.0 0.0 2.2e-08 33.9 0.0 3.4 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CEP17379.1 - 3.1e-13 49.7 0.4 9.5e-13 48.1 0.4 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CEP17379.1 - 8.9e-05 23.1 1.0 0.002 18.7 0.4 3.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CEP17379.1 - 0.031 14.4 0.5 0.12 12.6 0.5 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Elong_Iki1 PF10483.9 CEP17379.1 - 0.14 11.6 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Elongator subunit Iki1 Ribosomal_L7Ae PF01248.26 CEP17380.1 - 1.4e-26 92.0 0.2 2.5e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CEP17380.1 - 0.0007 19.7 0.0 0.00083 19.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 BAR PF03114.18 CEP17381.1 - 2.5e-38 132.1 4.7 4.4e-24 85.4 0.1 2.1 1 1 1 2 2 2 2 BAR domain BAR_3 PF16746.5 CEP17381.1 - 0.00024 20.9 1.2 0.0036 17.0 1.2 2.3 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 CEP17381.1 - 0.0004 20.0 1.8 0.0011 18.6 0.1 2.0 2 0 0 2 2 2 1 Arfaptin-like domain DUF4806 PF16064.5 CEP17381.1 - 0.0034 17.7 0.4 0.04 14.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) SKA2 PF16740.5 CEP17381.1 - 0.018 14.8 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF4107 PF13389.6 CEP17383.1 - 0.044 13.9 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) zf-CCHC PF00098.23 CEP17384.1 - 4.9e-08 32.7 5.0 1.5e-07 31.2 5.0 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEP17384.1 - 0.11 12.3 3.3 0.17 11.6 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle CAP_GLY PF01302.25 CEP17385.1 - 1.9e-18 66.2 0.2 4.4e-18 65.1 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain Sel1 PF08238.12 CEP17385.1 - 3.8e-18 65.5 9.9 0.032 14.9 0.0 5.6 5 0 0 5 5 5 5 Sel1 repeat CS PF04969.16 CEP17385.1 - 2e-10 41.6 0.1 8.2e-10 39.6 0.1 2.1 1 0 0 1 1 1 1 CS domain BTB PF00651.31 CEP17385.1 - 9.7e-10 38.7 0.1 2.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain CCDC158 PF15921.5 CEP17385.1 - 0.36 8.6 4.7 0.6 7.9 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 MIT PF04212.18 CEP17385.1 - 0.85 9.7 3.1 7.7 6.7 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Fungal_trans PF04082.18 CEP17386.1 - 2.6e-17 62.8 0.3 5.1e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.19 CEP17387.1 - 9.8e-16 57.9 0.3 3.1e-15 56.3 0.3 1.8 1 0 0 1 1 1 1 VHS domain U3_snoRNA_assoc PF08297.11 CEP17387.1 - 0.0022 18.6 6.1 0.0022 18.6 6.1 3.6 2 1 0 2 2 2 1 U3 snoRNA associated DUF4209 PF13910.6 CEP17387.1 - 0.025 14.8 2.4 0.13 12.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) Glyco_transf_10 PF00852.19 CEP17388.1 - 1.1e-40 139.2 0.2 1.6e-40 138.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CEP17388.1 - 7.2e-06 26.4 0.4 8.3e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 CEP17388.1 - 0.0094 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 CDC45 PF02724.14 CEP17389.1 - 1.3e-191 638.2 7.7 1.3e-191 638.2 7.7 3.6 3 1 0 3 3 3 1 CDC45-like protein GCFC PF07842.12 CEP17389.1 - 5.4e-71 239.4 24.1 1.1e-70 238.4 24.1 1.5 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 CEP17389.1 - 6e-13 48.5 1.7 6e-13 48.5 1.7 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CEP17389.1 - 6e-07 29.5 1.5 1.9e-06 27.8 1.5 1.9 1 0 0 1 1 1 1 G-patch domain MAF_flag10 PF01973.18 CEP17389.1 - 0.091 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 AAA_23 PF13476.6 CEP17389.1 - 0.73 10.3 9.9 2.1 8.8 9.9 1.8 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CEP17390.1 - 2.4e-20 72.5 3.3 0.00022 22.0 0.0 7.5 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17390.1 - 1.6e-06 28.3 0.0 0.62 10.4 0.0 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP17390.1 - 0.04 12.6 0.1 0.14 10.7 0.1 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ALG11_N PF15924.5 CEP17391.1 - 2.9e-90 301.9 2.4 4.3e-90 301.3 2.4 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CEP17391.1 - 1.3e-23 83.4 0.0 1.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP17391.1 - 3.5e-10 40.4 0.0 6.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CEP17391.1 - 0.0019 18.5 0.0 0.0058 17.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Crr6 PF08847.11 CEP17391.1 - 0.12 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 AHJR-like PF18743.1 CEP17391.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 REase_AHJR-like Fic_N PF13784.6 CEP17392.1 - 0.039 14.0 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Fic/DOC family N-terminal GIDA_assoc PF13932.6 CEP17392.1 - 0.58 10.3 4.7 0.22 11.7 1.9 1.6 2 0 0 2 2 2 0 GidA associated domain polyprenyl_synt PF00348.17 CEP17393.1 - 7.2e-64 215.3 0.0 8.5e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short_C2 PF13561.6 CEP17394.1 - 4.7e-09 36.2 0.0 4.7e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP17394.1 - 1.9e-07 30.7 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RanGAP1_C PF07834.11 CEP17395.1 - 0.068 12.8 0.6 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 RanGAP1 C-terminal domain DUF2046 PF09755.9 CEP17396.1 - 5.4e-31 108.0 32.3 8.2e-31 107.4 28.8 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) MCPVI PF02993.14 CEP17396.1 - 0.036 13.9 0.8 0.064 13.1 0.8 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DUF4349 PF14257.6 CEP17396.1 - 0.12 11.8 11.7 0.082 12.3 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3828 PF12883.7 CEP17396.1 - 1.4 9.3 12.7 20 5.6 6.2 3.5 1 1 2 4 4 4 0 Protein of unknown function (DUF3828) YbaB_DNA_bd PF02575.16 CEP17396.1 - 8 6.8 16.0 0.054 13.7 1.8 3.1 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family Peptidase_S8 PF00082.22 CEP17397.1 - 1.4e-78 264.2 0.2 3.7e-78 262.8 0.0 1.7 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.8 CEP17397.1 - 1.5e-50 171.3 0.4 2.4e-50 170.7 0.4 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II RNase_H2_suC PF08615.11 CEP17397.1 - 1.1 9.5 3.3 0.42 10.8 0.3 1.8 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2533 PF10752.9 CEP17398.1 - 2.1 8.8 5.2 2.7 8.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Sel1 PF08238.12 CEP17399.1 - 3.8e-128 415.0 57.0 6.1e-10 39.5 0.1 15.1 15 0 0 15 15 15 15 Sel1 repeat KID PF02524.14 CEP17399.1 - 1.4 9.3 3.0 12 6.5 0.1 3.3 3 0 0 3 3 3 0 KID repeat Fib_succ_major PF09603.10 CEP17399.1 - 2.5 8.7 7.9 14 6.3 0.1 4.0 1 1 3 4 4 4 0 Fibrobacter succinogenes major domain (Fib_succ_major) Ribosomal_S24e PF01282.19 CEP17401.1 - 6e-37 125.5 0.1 9.8e-37 124.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SpoU_methylase PF00588.19 CEP17402.1 - 6.2e-34 117.2 0.0 2.9e-33 115.0 0.0 2.1 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CEP17402.1 - 4e-14 52.6 0.0 7.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF190 PF02641.15 CEP17402.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 RAI16-like PF10257.9 CEP17403.1 - 2.3e-54 184.6 0.7 4.6e-54 183.7 0.7 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PCEMA1 PF07418.11 CEP17404.1 - 0.032 13.8 9.4 0.042 13.4 9.4 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Topoisom_I PF01028.20 CEP17406.1 - 5.5e-96 320.3 8.0 5.5e-96 320.3 8.0 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CEP17406.1 - 1.8e-95 318.5 3.0 1.8e-95 318.5 3.0 2.5 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CEP17406.1 - 1.3e-34 118.0 1.1 4.2e-34 116.3 1.1 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4718 PF15842.5 CEP17406.1 - 1.7 8.4 5.8 0.24 11.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Y_phosphatase2 PF03162.13 CEP17407.1 - 9e-59 197.7 0.2 1.7e-58 196.9 0.2 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CEP17407.1 - 2.7e-09 37.4 0.0 3.6e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CEP17407.1 - 2.9e-05 23.9 0.1 5.4e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP17407.1 - 0.00042 20.0 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GTP_EFTU PF00009.27 CEP17408.1 - 5.6e-56 189.2 0.1 1.1e-55 188.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CEP17408.1 - 3.2e-26 91.2 0.0 9e-26 89.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CEP17408.1 - 1.8e-18 66.4 0.0 1.3e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEP17408.1 - 9.5e-11 41.9 0.1 2.8e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEP17408.1 - 1e-07 31.9 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 CEP17408.1 - 9.3e-06 25.4 0.1 0.00019 21.2 0.1 3.0 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CEP17408.1 - 0.0023 18.0 0.1 0.0057 16.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CEP17408.1 - 0.12 11.6 0.0 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Septin PF00735.18 CEP17409.1 - 9.9e-106 353.1 0.1 9.9e-106 353.1 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEP17409.1 - 1.1e-07 31.9 0.0 2.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP17409.1 - 3.8e-07 29.8 2.3 1e-05 25.2 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP17409.1 - 1.3e-05 25.2 2.5 1.6e-05 24.9 0.2 2.3 3 0 0 3 3 2 1 RsgA GTPase Roc PF08477.13 CEP17409.1 - 0.00024 21.3 0.1 0.00059 20.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP17409.1 - 0.00028 20.5 0.1 0.00082 19.0 0.1 1.8 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 CEP17409.1 - 0.0025 18.1 0.7 0.0078 16.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain IIGP PF05049.13 CEP17409.1 - 0.0029 16.7 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.12 CEP17409.1 - 0.0063 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 CEP17409.1 - 0.012 15.4 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CEP17409.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 CEP17409.1 - 0.014 15.9 0.7 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Exonuc_VII_L PF02601.15 CEP17409.1 - 0.014 15.0 0.6 0.021 14.4 0.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_16 PF13191.6 CEP17409.1 - 0.016 15.6 0.2 0.049 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 CEP17409.1 - 0.017 14.9 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 CEP17409.1 - 0.017 14.6 0.1 0.04 13.4 0.1 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AIG1 PF04548.16 CEP17409.1 - 0.02 14.2 1.7 0.02 14.2 0.1 1.8 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.22 CEP17409.1 - 0.045 14.1 0.2 0.17 12.3 0.1 2.1 1 1 1 2 2 2 0 RNA helicase AAA_7 PF12775.7 CEP17409.1 - 0.064 12.8 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CEP17409.1 - 0.079 12.3 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CEP17409.1 - 0.086 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CEP17409.1 - 0.15 11.1 0.1 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CEP17409.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 CEP17409.1 - 0.17 11.9 4.6 6 6.9 0.1 3.2 2 1 1 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 CEP17409.1 - 0.17 11.6 2.6 2.8 7.7 0.5 3.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein PDEase_I PF00233.19 CEP17410.1 - 9.5e-68 228.5 7.0 1.4e-67 227.9 7.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CEP17410.1 - 1.3e-08 35.1 0.9 1.3e-08 35.1 0.9 2.1 2 1 0 2 2 2 1 HD domain RGS PF00615.19 CEP17411.1 - 2.6e-19 69.6 0.2 4.5e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2370 PF10176.9 CEP17412.1 - 2.5e-71 239.9 5.6 9.7e-70 234.7 0.7 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) PS_Dcarbxylase PF02666.15 CEP17413.1 - 9e-57 191.9 0.0 1.5e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CEP17413.1 - 5.1e-35 119.9 0.1 1e-19 70.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CEP17413.1 - 0.0057 16.2 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 CEP76 C2 domain PepSY_2 PF13670.6 CEP17413.1 - 0.049 13.6 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain UBZ_FAAP20 PF15750.5 CEP17413.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DUF5634 PF18681.1 CEP17414.1 - 0.068 13.5 0.2 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5634) LRR_4 PF12799.7 CEP17415.1 - 0.00016 22.0 13.9 1.1 9.8 0.1 6.4 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CEP17415.1 - 7.8 6.8 0.0 7.8 6.8 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat zf-piccolo PF05715.13 CEP17416.1 - 0.043 14.0 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Piccolo Zn-finger Aldo_ket_red PF00248.21 CEP17417.1 - 1.3e-49 169.0 0.1 9.4e-48 162.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CH PF00307.31 CEP17417.1 - 0.15 12.2 0.3 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF1394 PF07159.12 CEP17418.1 - 3.1e-97 325.5 1.4 3.5e-97 325.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ras PF00071.22 CEP17419.1 - 4.3e-49 166.2 0.4 6.5e-49 165.6 0.4 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CEP17419.1 - 2.2e-15 56.9 0.0 1.8e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEP17419.1 - 0.00012 21.6 0.1 0.00028 20.5 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CEP17419.1 - 0.00024 20.6 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEP17419.1 - 0.0041 17.0 0.0 0.41 10.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase zf-CCHC_6 PF15288.6 CEP17421.1 - 0.011 15.6 0.4 0.018 14.9 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 CEP17421.1 - 0.34 11.1 1.9 1.9 8.7 1.9 2.2 1 1 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP17421.1 - 0.9 9.3 3.4 1.5 8.7 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle Abhydrolase_1 PF00561.20 CEP17422.1 - 2.3e-24 86.4 0.0 1.2e-22 80.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP17422.1 - 2.7e-21 77.2 0.0 3.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP17422.1 - 9.8e-15 54.5 0.0 1.4e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CEP17422.1 - 2.7e-06 27.3 0.1 0.00012 21.9 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CEP17422.1 - 0.00022 21.4 0.0 0.0004 20.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 CEP17422.1 - 0.00037 19.3 0.0 0.096 11.4 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydro_lipase PF04083.16 CEP17422.1 - 0.0045 16.5 0.2 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Esterase PF00756.20 CEP17422.1 - 0.0045 16.7 0.0 0.0078 15.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 CEP17422.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PAF-AH_p_II PF03403.13 CEP17422.1 - 0.08 11.4 0.1 5.2 5.5 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S10 PF00450.22 CEP17422.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.5 1 1 0 1 1 1 0 Serine carboxypeptidase DUF2052 PF09747.9 CEP17423.1 - 1.8 8.7 20.6 4.1 7.5 20.6 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) UQ_con PF00179.26 CEP17424.1 - 1.9e-48 163.7 0.0 2.2e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CEP17424.1 - 0.00022 20.9 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CEP17424.1 - 0.049 13.9 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain BRE PF06113.12 CEP17424.1 - 0.077 11.8 0.1 0.098 11.5 0.1 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) PRP3 PF08572.10 CEP17425.1 - 7.4e-73 245.0 10.5 7.4e-73 245.0 10.5 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CEP17425.1 - 5.9e-45 152.9 0.4 1.4e-44 151.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) FliX PF10768.9 CEP17425.1 - 0.0047 17.4 1.4 0.018 15.6 1.4 2.0 1 0 0 1 1 1 1 Class II flagellar assembly regulator YfcL PF08891.11 CEP17425.1 - 0.46 10.9 3.5 0.24 11.8 0.7 2.0 2 0 0 2 2 2 0 YfcL protein Ribosomal_L44 PF00935.19 CEP17426.1 - 1.3e-37 128.1 10.1 2e-37 127.5 10.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 XPG_I PF00867.18 CEP17427.1 - 9e-21 74.0 0.1 3e-20 72.4 0.1 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CEP17427.1 - 7.8e-20 71.2 0.0 2.1e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CEP17427.1 - 0.00025 20.6 0.1 0.0005 19.6 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_1 PF00515.28 CEP17427.1 - 0.0007 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEP17427.1 - 0.0012 18.8 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat HemY_N PF07219.13 CEP17427.1 - 0.036 14.3 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TPR_16 PF13432.6 CEP17427.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1388 PF07142.12 CEP17427.1 - 1.6 8.8 11.1 3.9 7.5 11.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Myb_DNA-bind_4 PF13837.6 CEP17428.1 - 0.0021 18.4 0.3 0.0066 16.8 0.3 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TFIIA PF03153.13 CEP17428.1 - 0.037 14.0 12.8 0.049 13.6 12.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UBA_3 PF09288.10 CEP17428.1 - 0.16 11.8 1.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Glyco_hydro_9 PF00759.19 CEP17429.1 - 6.2e-94 315.7 21.2 6.2e-94 315.7 21.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 IBR PF01485.21 CEP17429.1 - 3.1e-07 30.5 7.8 3.1e-07 30.5 7.8 4.6 2 1 2 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CEP17429.1 - 0.0038 17.0 6.6 0.0038 17.0 6.6 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PE PF00934.20 CEP17429.1 - 0.036 14.4 2.1 0.09 13.1 2.1 1.7 1 0 0 1 1 1 0 PE family DUF4451 PF14616.6 CEP17429.1 - 0.16 12.2 14.6 0.11 12.7 7.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Presenilin PF01080.17 CEP17429.1 - 0.19 10.5 0.7 0.34 9.6 0.7 1.4 1 0 0 1 1 1 0 Presenilin DUF908 PF06012.12 CEP17429.1 - 0.38 10.1 13.7 0.64 9.4 13.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SPT6_acidic PF14632.6 CEP17429.1 - 3.2 8.4 14.9 0.38 11.4 3.3 3.1 3 0 0 3 3 3 0 Acidic N-terminal SPT6 zf-C3HC4 PF00097.25 CEP17430.1 - 1.7e-07 31.0 9.2 3.5e-07 30.0 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP17430.1 - 5.8e-07 29.3 5.9 9.9e-07 28.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP17430.1 - 7.2e-07 29.0 5.1 6.2e-05 22.7 7.1 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP17430.1 - 1.6e-06 28.3 8.7 4.4e-06 26.9 8.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP17430.1 - 2.3e-06 27.5 6.1 2.3e-06 27.5 6.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CEP17430.1 - 1.2e-05 25.2 6.5 2.6e-05 24.1 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEP17430.1 - 0.0014 18.5 5.2 0.0036 17.1 5.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 CEP17430.1 - 0.0032 17.2 9.7 0.012 15.4 9.7 2.0 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 CEP17430.1 - 0.0035 17.5 7.9 0.011 15.8 7.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CEP17430.1 - 0.029 14.4 1.8 0.06 13.4 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEP17430.1 - 0.037 14.3 5.5 0.094 13.0 5.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 CEP17430.1 - 0.04 13.8 3.8 0.1 12.4 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 CEP17430.1 - 0.079 13.1 1.0 0.21 11.8 1.0 1.7 1 0 0 1 1 1 0 FYVE zinc finger RecR PF02132.15 CEP17430.1 - 0.11 12.0 0.9 15 5.3 0.2 2.8 2 0 0 2 2 2 0 RecR protein zf-RING_11 PF17123.5 CEP17430.1 - 2 8.2 7.7 7.2 6.5 4.5 2.6 2 0 0 2 2 2 0 RING-like zinc finger Pet20 PF08692.10 CEP17430.1 - 4.5 8.0 6.3 1.5 9.5 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial protein Pet20 FYDLN_acid PF09538.10 CEP17430.1 - 6.9 7.4 8.6 0.35 11.6 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ysc84 PF04366.12 CEP17431.1 - 2.1e-44 150.4 0.5 3.4e-44 149.7 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CEP17431.1 - 9.6e-17 60.3 0.4 2.2e-16 59.2 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CEP17431.1 - 1.4e-16 60.0 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP17431.1 - 2.8e-11 42.9 0.0 5.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3605 PF12239.8 CEP17432.1 - 2.5e-27 96.1 0.6 8.6e-26 91.1 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) CM_2 PF01817.21 CEP17433.1 - 0.0003 21.1 0.6 0.16 12.3 0.0 2.5 2 1 0 2 2 2 2 Chorismate mutase type II CoA_transf_3 PF02515.17 CEP17434.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III Metallothio_Pro PF02069.16 CEP17434.1 - 0.094 13.0 0.5 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic metallothionein DNA_pol_phi PF04931.13 CEP17435.1 - 3.7 5.6 18.1 5.6 4.9 18.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-HC5HC2H_2 PF13832.6 CEP17436.1 - 1.3e-32 112.3 10.8 1.3e-32 112.3 10.8 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEP17436.1 - 1.8e-25 89.0 17.1 2.6e-25 88.5 9.0 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 CEP17436.1 - 5.2e-22 78.9 19.6 5.2e-22 78.9 19.6 5.3 4 3 0 4 4 4 2 Enhancer of polycomb-like Bromodomain PF00439.25 CEP17436.1 - 6.3e-18 64.6 0.6 1.6e-17 63.3 0.6 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 CEP17436.1 - 1.1e-14 53.6 3.5 1.1e-14 53.6 3.5 2.7 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 CEP17436.1 - 2e-11 43.6 23.5 1.5e-10 40.8 6.0 2.9 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 CEP17436.1 - 4.4e-05 23.8 0.9 0.00021 21.6 0.0 2.8 2 0 0 2 2 2 1 PWWP domain C1_1 PF00130.22 CEP17436.1 - 0.027 14.4 0.3 0.027 14.4 0.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CEP17436.1 - 0.081 12.9 18.9 0.11 12.5 5.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CEP17436.1 - 0.14 12.5 13.0 0.63 10.4 0.7 2.9 2 0 0 2 2 2 0 C1 domain CENP-F_leu_zip PF10473.9 CEP17437.1 - 0.0024 17.9 3.7 0.0039 17.2 3.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OrfB_Zn_ribbon PF07282.11 CEP17437.1 - 0.33 10.9 3.6 3.9 7.5 2.7 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF641 PF04859.12 CEP17437.1 - 0.66 10.3 5.7 0.77 10.1 1.2 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF3837 PF12939.7 CEP17438.1 - 0.075 13.4 0.0 0.87 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) CTD_bind PF04818.13 CEP17440.1 - 8.9e-08 32.9 0.0 2.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 CEP17440.1 - 1.2e-06 28.3 0.2 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CEP17440.1 - 4.4 7.2 20.5 9.2 6.1 20.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosom_S12_S23 PF00164.25 CEP17441.1 - 6.3e-38 128.9 0.8 9.7e-38 128.3 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 CEP17442.1 - 1.1e-57 191.9 0.8 6.7e-22 77.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP17442.1 - 0.00085 18.6 3.0 0.031 13.4 0.1 2.7 1 1 1 3 3 3 2 Gammaproteobacterial serine protease Brr6_like_C_C PF10104.9 CEP17443.1 - 1.3e-35 122.0 4.2 1.7e-35 121.7 4.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain UPF0181 PF03701.14 CEP17443.1 - 0.12 12.1 0.5 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Rab3-GTPase_cat PF13890.6 CEP17446.1 - 1.5e-56 190.6 0.5 3.4e-56 189.4 0.5 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit TANGO2 PF05742.12 CEP17446.1 - 0.074 13.1 0.0 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Transport and Golgi organisation 2 Glycos_transf_2 PF00535.26 CEP17448.1 - 1.6e-33 115.9 0.0 2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEP17448.1 - 1e-12 48.5 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CEP17448.1 - 5.8e-05 22.7 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEP17448.1 - 0.0079 15.7 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF2834 PF11196.8 CEP17449.1 - 3.9e-08 33.5 2.9 3.9e-08 33.5 2.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2834) PP2C PF00481.21 CEP17450.1 - 2.5e-11 43.7 0.0 1.3e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CEP17450.1 - 0.00055 19.6 0.0 0.0026 17.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C YmaF PF12788.7 CEP17450.1 - 0.033 14.7 0.1 0.072 13.6 0.1 1.5 1 0 0 1 1 1 0 YmaF family Na_trans_assoc PF06512.13 CEP17450.1 - 4.1 7.6 10.8 2.1 8.6 4.0 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated TFIIA PF03153.13 CEP17451.1 - 6.4 6.7 21.3 9 6.2 21.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 CEP17452.1 - 7.4e-07 29.4 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain SDH_sah PF01972.16 CEP17452.1 - 0.051 12.6 0.3 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Serine dehydrogenase proteinase RcnB PF11776.8 CEP17452.1 - 0.3 11.2 2.6 0.73 9.9 2.6 1.7 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator PTPRCAP PF15713.5 CEP17452.1 - 0.37 11.1 14.3 0.79 10.0 14.3 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EOS1 PF12326.8 CEP17452.1 - 0.96 9.4 3.9 7 6.5 3.9 2.2 1 1 0 1 1 1 0 N-glycosylation protein Bromodomain PF00439.25 CEP17453.1 - 1e-16 60.7 1.2 1e-16 60.7 1.2 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 CEP17453.1 - 6.1e-10 39.0 0.2 3.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated PFL-like PF02901.15 CEP17453.1 - 0.0026 16.5 0.4 0.0063 15.2 0.1 1.7 2 0 0 2 2 2 1 Pyruvate formate lyase-like Bromo_TP_like PF17027.5 CEP17453.1 - 0.0041 17.3 0.1 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Histone-fold protein PUF PF00806.19 CEP17454.1 - 6.2e-65 211.4 18.9 1.1e-08 34.3 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat tRNA_bind PF01588.20 CEP17455.1 - 4.5e-29 100.4 0.0 1.3e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 CEP17455.1 - 0.0028 17.8 0.1 0.0078 16.4 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP17455.1 - 0.0037 17.4 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CEP17455.1 - 0.0042 16.8 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP17455.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ras PF00071.22 CEP17456.1 - 6.1e-60 201.5 0.1 7.3e-60 201.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP17456.1 - 7.4e-21 74.6 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP17456.1 - 2e-07 30.6 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP17456.1 - 0.00057 19.5 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP17456.1 - 0.00061 19.7 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CEP17456.1 - 0.0066 16.5 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 CEP17456.1 - 0.076 12.2 0.0 9.2 5.3 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit InvH PF04741.12 CEP17457.1 - 0.048 13.6 0.6 0.048 13.6 0.6 2.0 2 0 0 2 2 2 0 InvH outer membrane lipoprotein Cofilin_ADF PF00241.20 CEP17458.1 - 1.5e-32 111.9 2.5 3.7e-18 65.5 1.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Cyclin PF08613.11 CEP17459.1 - 1.3e-40 139.5 1.1 1.8e-40 139.0 1.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP17459.1 - 0.00043 20.0 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ThrE PF06738.12 CEP17460.1 - 3.4e-44 151.0 26.3 6.2e-41 140.3 7.4 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CEP17460.1 - 4.2e-07 30.1 26.7 1.6e-06 28.3 10.5 2.7 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE DUF4225 PF13988.6 CEP17460.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) MHYT PF03707.16 CEP17460.1 - 8 6.7 12.1 1.2 9.4 0.1 4.2 5 0 0 5 5 5 0 Bacterial signalling protein N terminal repeat DEAD PF00270.29 CEP17461.1 - 2.3e-37 128.4 0.4 1.2e-34 119.6 0.1 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17461.1 - 2.2e-31 108.5 0.0 8.1e-31 106.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP17461.1 - 0.014 15.4 0.2 0.13 12.2 0.0 2.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit MtlR PF05068.12 CEP17461.1 - 0.18 11.8 1.4 0.3 11.1 1.4 1.3 1 0 0 1 1 1 0 Mannitol repressor DUF5093 PF17011.5 CEP17461.1 - 8.9 6.6 8.6 0.85 9.9 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5093) Sod_Cu PF00080.20 CEP17463.1 - 8.9e-43 145.9 2.6 1.1e-42 145.5 2.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Phytoreo_S7 PF07236.11 CEP17464.1 - 0.031 12.6 0.1 0.036 12.4 0.1 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF4993 PF16384.5 CEP17465.1 - 0.085 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Ank_2 PF12796.7 CEP17466.1 - 1.3e-27 96.2 8.1 2.9e-17 63.0 2.8 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP17466.1 - 4e-26 91.1 4.9 2.9e-11 43.7 0.7 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP17466.1 - 1.9e-22 79.0 5.0 1.7e-09 37.7 0.0 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP17466.1 - 3.4e-18 63.8 5.0 0.00047 20.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat FYVE PF01363.21 CEP17466.1 - 3.8e-17 62.2 7.6 3.8e-17 62.2 7.6 2.3 2 0 0 2 2 2 1 FYVE zinc finger Ank PF00023.30 CEP17466.1 - 8.2e-11 41.9 9.1 0.0013 19.1 0.2 5.0 4 1 1 5 5 5 3 Ankyrin repeat Trm112p PF03966.16 CEP17466.1 - 0.0092 16.5 0.2 0.041 14.5 0.0 2.2 2 0 0 2 2 2 1 Trm112p-like protein HypA PF01155.19 CEP17466.1 - 0.23 11.5 6.4 0.065 13.3 1.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 CEP17466.1 - 0.61 10.3 12.4 0.49 10.6 9.0 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger DUF2039 PF10217.9 CEP17466.1 - 0.65 10.4 9.5 0.29 11.5 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RNA_pol_Rpb1_1 PF04997.12 CEP17467.1 - 1.6e-115 385.8 0.0 2.9e-115 384.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CEP17467.1 - 1.9e-106 355.4 0.5 3.3e-106 354.6 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEP17467.1 - 4.5e-76 254.7 1.1 6.3e-76 254.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CEP17467.1 - 5.8e-67 225.2 0.6 5.8e-67 225.2 0.6 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CEP17467.1 - 3.1e-51 173.4 0.0 1.1e-50 171.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 CEP17467.1 - 1.1e-48 164.6 5.3 1.1e-48 164.6 5.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 CEP17467.1 - 4e-39 132.9 0.7 1.1e-38 131.5 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CEP17467.1 - 7.9e-14 51.2 360.4 0.11 12.9 12.8 17.5 4 2 18 25 25 25 23 RNA polymerase Rpb1 C-terminal repeat p450 PF00067.22 CEP17468.1 - 2.6e-36 125.4 0.0 9.8e-36 123.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 DUF4602 PF15375.6 CEP17469.1 - 0.00058 20.2 12.6 0.00058 20.2 12.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) FA_FANCE PF11510.8 CEP17470.1 - 8.5e-07 28.6 4.7 2.6e-06 27.0 1.0 2.4 1 1 1 2 2 2 2 Fanconi Anaemia group E protein FANCE MFS_1 PF07690.16 CEP17471.1 - 4.5e-26 91.6 31.1 6.4e-26 91.1 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Vps8 PF12816.7 CEP17473.1 - 3.5e-69 232.3 0.1 1.1e-66 224.1 0.0 2.9 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CEP17473.1 - 2e-07 30.9 3.6 0.0099 15.8 0.0 3.8 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.6 CEP17473.1 - 0.0015 18.8 2.0 0.0015 18.8 2.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CEP17473.1 - 0.0016 18.4 2.3 0.0037 17.2 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CEP17473.1 - 0.0019 18.5 0.9 0.0047 17.2 0.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain WD40 PF00400.32 CEP17473.1 - 0.017 16.0 0.3 0.079 13.9 0.3 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CEP17473.1 - 0.092 12.6 8.1 0.015 15.2 3.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP17473.1 - 0.36 10.7 2.6 0.34 10.8 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP17473.1 - 0.72 9.9 2.3 2.6 8.1 2.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP17473.1 - 1.3 9.0 6.3 0.2 11.6 2.2 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ACOX PF01756.19 CEP17474.1 - 9e-51 172.0 0.0 1.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CEP17474.1 - 1.8e-20 72.9 0.1 3.8e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CEP17474.1 - 2.8e-15 57.0 0.1 6.4e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CEP17474.1 - 1e-07 32.3 0.4 8.6e-07 29.3 0.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vps53_N PF04100.12 CEP17475.1 - 2.4e-99 332.9 9.7 2.4e-99 332.9 9.7 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal VPS53_C PF16854.5 CEP17475.1 - 2e-07 31.1 1.1 5.1e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF237 PF03072.14 CEP17475.1 - 0.049 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF237) V_ATPase_I PF01496.19 CEP17475.1 - 0.22 9.4 9.2 0.1 10.5 5.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 CEP17475.1 - 0.59 10.2 8.0 22 5.1 2.2 4.1 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 HeLo PF14479.6 CEP17475.1 - 1.2 8.9 6.0 29 4.4 0.0 2.6 2 0 0 2 2 2 0 Prion-inhibition and propagation Vps51 PF08700.11 CEP17475.1 - 3.1 7.9 7.7 10 6.3 0.1 3.3 2 1 0 2 2 2 0 Vps51/Vps67 NDC10_II PF16787.5 CEP17476.1 - 2.4e-22 79.4 0.0 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 PAS_2 PF08446.11 CEP17477.1 - 0.12 13.0 0.5 0.64 10.7 0.1 2.5 2 0 0 2 2 2 0 PAS fold WD40_3 PF15911.5 CEP17477.1 - 0.12 12.3 0.2 12 6.0 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat SDA1 PF05285.12 CEP17478.1 - 1e-86 291.5 30.2 1e-86 291.5 30.2 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 CEP17478.1 - 2.8e-24 85.2 0.3 2.8e-24 85.2 0.3 2.0 2 0 0 2 2 2 1 NUC130/3NT domain Mating_N PF12731.7 CEP17478.1 - 0.024 14.7 0.1 0.079 13.1 0.1 1.9 1 0 0 1 1 1 0 Mating-type protein beta 1 Porin_3 PF01459.22 CEP17479.1 - 2.7e-67 227.1 10.1 3.1e-67 226.9 10.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin TGT PF01702.18 CEP17480.1 - 3e-147 490.3 0.0 3.5e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Phage_holin_2_3 PF16080.5 CEP17481.1 - 0.028 14.2 0.1 6.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Pro_isomerase PF00160.21 CEP17482.1 - 6.6e-47 159.7 0.1 6.6e-47 159.7 0.1 2.1 2 1 0 2 2 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spem1 PF15670.5 CEP17482.1 - 0.051 13.2 11.8 0.073 12.6 11.8 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 SLC12 PF03522.15 CEP17482.1 - 0.2 10.6 17.1 0.28 10.2 17.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 CEP17482.1 - 0.48 9.1 13.2 0.66 8.6 13.2 1.1 1 0 0 1 1 1 0 Raftlin SAGA-Tad1 PF12767.7 CEP17482.1 - 0.87 9.3 14.5 1.3 8.8 14.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LAP1C PF05609.12 CEP17482.1 - 1 8.4 17.5 1.4 7.9 17.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 CEP17482.1 - 1.5 7.4 8.7 1.7 7.2 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TP53IP5 PF15331.6 CEP17482.1 - 3.4 7.8 17.0 5.1 7.2 17.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 ALMT PF11744.8 CEP17482.1 - 3.9 6.2 13.3 5.1 5.8 13.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Menin PF05053.13 CEP17482.1 - 4.4 5.5 9.8 5.8 5.1 9.8 1.1 1 0 0 1 1 1 0 Menin DUF4661 PF15576.6 CEP17482.1 - 5 7.0 15.1 7.4 6.4 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Neur_chan_memb PF02932.16 CEP17482.1 - 5.2 7.1 12.3 7.4 6.5 12.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPRTase PF14681.6 CEP17483.1 - 1.4e-65 220.7 0.0 2.1e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 CEP17483.1 - 1.4e-62 211.0 0.1 2.4e-62 210.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 CEP17483.1 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CEP17483.1 - 0.0019 18.8 0.0 0.0039 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CEP17483.1 - 0.0019 17.9 0.4 0.041 13.5 0.4 2.2 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 CEP17483.1 - 0.0021 18.2 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF981 PF06168.11 CEP17483.1 - 0.0036 17.3 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF981) AAA_17 PF13207.6 CEP17483.1 - 0.14 12.6 0.0 8.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CEP17483.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SKG6 PF08693.10 CEP17484.1 - 8.2 5.9 9.5 0.57 9.6 2.3 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain RRM_1 PF00076.22 CEP17485.1 - 8.1e-32 108.9 0.2 2e-15 56.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP17485.1 - 3.3e-06 27.1 0.6 0.011 15.7 0.0 2.3 1 1 1 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 CEP17485.1 - 0.00024 21.1 0.6 0.072 13.2 0.1 2.6 1 1 1 2 2 2 2 Limkain b1 RRM_5 PF13893.6 CEP17485.1 - 0.0003 20.4 0.0 0.42 10.2 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CEP17485.1 - 0.035 13.7 0.3 11 5.8 0.1 2.6 2 1 0 2 2 2 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 CEP17485.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MatE PF01554.18 CEP17486.1 - 3.6e-46 156.7 34.3 2.7e-29 101.9 11.8 2.4 2 0 0 2 2 2 2 MatE MOZ_SAS PF01853.18 CEP17487.1 - 2.6e-83 278.1 0.7 2.6e-83 278.1 0.7 1.8 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 CEP17487.1 - 1.1e-21 76.1 2.9 1.1e-21 76.1 2.9 2.7 3 0 0 3 3 3 1 MYST family zinc finger domain PHD PF00628.29 CEP17487.1 - 8.9e-13 47.9 29.9 4.4e-11 42.5 12.2 3.5 2 1 1 3 3 3 2 PHD-finger TFIIE_beta PF02186.15 CEP17487.1 - 0.065 13.5 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain AT_hook PF02178.19 CEP17487.1 - 0.44 10.6 4.7 1.2 9.3 4.7 1.8 1 0 0 1 1 1 0 AT hook motif Smg4_UPF3 PF03467.15 CEP17487.1 - 1.1 9.3 6.1 1.2 9.1 5.0 1.7 1 1 1 2 2 2 0 Smg-4/UPF3 family FAD_binding_6 PF00970.24 CEP17488.1 - 3.1e-31 107.7 0.0 4.8e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CEP17488.1 - 6.3e-28 97.6 0.0 9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CEP17488.1 - 1.3e-07 31.9 0.0 1.8e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sugar_tr PF00083.24 CEP17489.1 - 2.1e-45 155.4 21.9 1.8e-27 96.3 6.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP17489.1 - 8.2e-19 67.7 38.1 1.2e-09 37.5 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.28 CEP17490.1 - 3.4e-16 58.3 1.8 4.4e-05 23.1 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 CEP17490.1 - 1.1e-10 41.0 1.0 0.00025 20.6 0.0 4.3 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.17 CEP17490.1 - 1.1e-09 37.6 2.7 0.00021 21.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP17490.1 - 5.7e-07 30.1 2.1 0.11 13.2 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP17490.1 - 1.4e-06 28.7 5.8 0.0015 19.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17490.1 - 2.6e-06 27.2 1.0 0.011 15.8 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEP17490.1 - 3.5e-06 27.3 2.6 0.0042 17.4 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17490.1 - 5e-06 26.9 6.9 2.1 9.4 0.1 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP17490.1 - 1.6e-05 24.9 3.1 0.002 18.4 0.1 3.9 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP17490.1 - 2.8e-05 24.2 5.3 0.013 15.7 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17490.1 - 4.4e-05 23.7 8.3 0.028 14.7 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP17490.1 - 0.00031 20.5 0.2 0.57 10.3 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP17490.1 - 0.00036 20.3 0.6 0.0035 17.2 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP17490.1 - 0.0051 17.4 1.3 0.81 10.5 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat HD_3 PF13023.6 CEP17491.1 - 7.4e-45 152.8 0.4 9.1e-45 152.5 0.4 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CEP17491.1 - 2.8e-10 40.2 0.3 4.2e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CEP17491.1 - 1.6e-05 25.1 0.1 3.2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 HD domain SapC PF07277.11 CEP17491.1 - 0.01 15.5 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 1 SapC MMR_HSR1 PF01926.23 CEP17492.1 - 4.9e-16 58.8 0.0 8e-14 51.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP17492.1 - 1.4e-06 28.3 0.1 0.00025 21.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CEP17492.1 - 2.2e-05 24.0 0.1 0.00042 19.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AIG1 PF04548.16 CEP17492.1 - 0.005 16.2 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CEP17492.1 - 0.0057 16.7 1.5 0.022 14.8 0.1 2.5 2 2 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 CEP17492.1 - 0.012 15.2 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 CEP17492.1 - 0.013 15.7 0.5 0.069 13.4 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CEP17492.1 - 0.021 14.6 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CEP17492.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Septin ASCH PF04266.14 CEP17492.1 - 0.14 12.7 1.3 0.41 11.2 1.3 1.7 1 0 0 1 1 1 0 ASCH domain ABC_tran PF00005.27 CEP17492.1 - 0.17 12.4 0.0 1.9 9.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter GAT PF03127.14 CEP17493.1 - 6.5e-09 36.0 2.4 6.7e-09 35.9 0.7 2.0 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 CEP17493.1 - 2.4e-08 33.9 0.0 0.002 18.0 0.0 2.6 1 1 1 2 2 2 2 VHS domain RhoGAP PF00620.27 CEP17494.1 - 3.4e-38 130.8 0.0 5.8e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain QCR10 PF09796.9 CEP17494.1 - 3.7e-15 55.7 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_16 PF00722.21 CEP17495.1 - 3.1e-29 101.7 0.6 4.2e-29 101.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LpoB PF13036.6 CEP17496.1 - 0.39 10.6 4.5 0.072 13.0 0.6 1.8 2 0 0 2 2 2 0 Peptidoglycan-synthase activator LpoB ANAPC_CDC26 PF10471.9 CEP17496.1 - 5.7 7.8 8.7 4.6 8.1 2.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Ribonuc_P_40 PF08584.11 CEP17497.1 - 2.8e-58 197.4 0.4 4.8e-58 196.7 0.4 1.4 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Thioredoxin PF00085.20 CEP17497.1 - 4e-55 184.2 0.3 2.8e-27 94.7 0.1 4.3 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CEP17497.1 - 7.7e-30 104.2 1.1 2.2e-21 76.6 0.1 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CEP17497.1 - 3e-11 43.8 0.4 0.034 14.6 0.0 4.6 3 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP17497.1 - 4e-09 36.7 0.6 0.013 15.8 0.0 5.6 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CEP17497.1 - 4.2e-07 30.0 0.2 0.038 14.2 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CEP17497.1 - 8.4e-07 28.6 1.5 0.0039 16.6 0.1 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CEP17497.1 - 9.8e-06 25.5 0.4 0.27 11.2 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 CEP17497.1 - 0.0003 20.5 0.6 4.1 7.1 0.1 3.4 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 CEP17497.1 - 0.0022 18.1 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 1 ERp29, N-terminal domain BTG PF07742.12 CEP17498.1 - 6e-34 116.4 0.0 9.4e-34 115.7 0.0 1.3 1 0 0 1 1 1 1 BTG family Lebercilin PF15619.6 CEP17499.1 - 0.013 15.1 7.9 0.32 10.6 6.8 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Dus PF01207.17 CEP17499.1 - 0.028 13.5 1.9 0.22 10.6 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) APG6_N PF17675.1 CEP17499.1 - 0.069 13.7 8.3 0.15 12.6 8.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 CEP17499.1 - 0.077 12.6 6.2 0.19 11.3 6.2 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2890 PF11081.8 CEP17499.1 - 0.11 12.6 7.4 0.09 12.9 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) XhlA PF10779.9 CEP17499.1 - 0.34 11.1 5.6 0.11 12.8 1.1 2.4 3 0 0 3 3 3 0 Haemolysin XhlA BLOC1_2 PF10046.9 CEP17499.1 - 3.6 8.0 10.8 2.9 8.3 3.3 3.6 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MFS_2 PF13347.6 CEP17500.1 - 2.2e-05 23.2 21.6 2.2e-05 23.2 21.6 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein DUF962 PF06127.11 CEP17500.1 - 0.87 9.7 8.9 0.29 11.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF962) Methyltransf_25 PF13649.6 CEP17501.1 - 2.3e-15 57.1 0.0 5.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP17501.1 - 2e-13 50.8 0.0 9.1e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP17501.1 - 2.6e-12 46.9 0.0 4.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP17501.1 - 2.3e-10 41.1 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP17501.1 - 6.7e-10 39.0 0.0 2.4e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP17501.1 - 2.9e-08 33.4 0.0 5.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CEP17501.1 - 1.2e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CEP17501.1 - 0.00019 21.0 0.0 0.0013 18.2 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 CEP17501.1 - 0.00049 20.3 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 CEP17501.1 - 0.00092 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 CEP17501.1 - 0.0023 17.4 0.0 0.014 14.9 0.0 2.2 3 0 0 3 3 3 1 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.18 CEP17501.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 CEP17501.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 CEP17501.1 - 0.12 13.4 0.0 0.3 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SMN PF06003.12 CEP17502.1 - 1.5e-06 27.7 3.0 2e-06 27.3 3.0 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF1325 PF07039.11 CEP17502.1 - 2.3e-05 24.5 0.3 6.4e-05 23.1 0.3 1.9 1 1 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 CEP17502.1 - 7.4e-05 22.5 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 CEP17502.1 - 0.00018 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CEP17502.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 CEP17502.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 CEP17502.1 - 0.057 13.5 0.2 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Tudor domain DUF2730 PF10805.8 CEP17502.1 - 0.059 13.5 0.4 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) BBS2_C PF14782.6 CEP17502.1 - 0.07 11.9 0.2 0.097 11.4 0.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DMAP1 PF05499.12 CEP17502.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.2 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Sds3 PF08598.11 CEP17503.1 - 2.9e-15 56.8 14.3 5.3e-15 56.0 14.3 1.3 1 0 0 1 1 1 1 Sds3-like zf-C2H2_4 PF13894.6 CEP17504.1 - 5.7e-06 26.7 83.8 0.052 14.4 2.8 10.5 11 0 0 11 11 11 7 C2H2-type zinc finger zf-met PF12874.7 CEP17504.1 - 2.8e-05 24.4 62.2 0.012 16.0 1.7 9.4 10 0 0 10 10 10 5 Zinc-finger of C2H2 type zf_C2H2_13 PF18508.1 CEP17504.1 - 0.011 15.3 4.6 1.8 8.2 0.0 3.8 3 0 0 3 3 3 0 Zinc finger domain zf-C2H2_jaz PF12171.8 CEP17504.1 - 0.014 15.7 2.5 0.014 15.7 2.5 9.3 10 0 0 10 10 10 0 Zinc-finger double-stranded RNA-binding FAM35_C PF15793.5 CEP17504.1 - 0.47 9.8 3.6 3 7.2 0.3 3.2 3 0 0 3 3 3 0 Protein family FAM35, C-terminal GBP_repeat PF02526.14 CEP17504.1 - 1.2 8.9 6.7 5.6 6.8 0.1 4.0 4 0 0 4 4 4 0 Glycophorin-binding protein zf-C2H2_3rep PF18868.1 CEP17504.1 - 6.5 7.4 25.8 9.9 6.9 0.2 6.8 4 2 3 8 8 8 0 Zinc finger C2H2-type, 3 repeats Glyco_hydro_16 PF00722.21 CEP17505.1 - 2e-19 69.8 0.4 3e-19 69.2 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pro_isomerase PF00160.21 CEP17507.1 - 6.6e-50 169.5 0.0 7.5e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NYD-SP28_assoc PF14775.6 CEP17508.1 - 0.21 11.7 0.8 0.41 10.8 0.8 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Retrotrans_gag PF03732.17 CEP17509.1 - 2e-06 28.0 3.3 7.5e-06 26.1 0.1 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP17509.1 - 2.2e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Phage_int_SAM_4 PF13495.6 CEP17510.1 - 0.38 11.3 4.5 4.8 7.7 0.2 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain NDC10_II PF16787.5 CEP17511.1 - 0.13 11.3 0.2 0.26 10.3 0.1 1.6 1 1 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF4407 PF14362.6 CEP17513.1 - 0.00085 18.8 11.3 0.00097 18.6 11.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SpoVR PF04293.13 CEP17513.1 - 0.016 13.9 6.8 0.019 13.7 6.8 1.0 1 0 0 1 1 1 0 SpoVR like protein GAGA_bind PF06217.12 CEP17513.1 - 0.037 14.3 10.6 0.04 14.2 10.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SKA1 PF07160.12 CEP17513.1 - 0.065 13.1 17.0 0.082 12.7 17.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SSP160 PF06933.11 CEP17513.1 - 0.12 10.5 2.9 0.14 10.4 2.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DivIC PF04977.15 CEP17513.1 - 0.17 11.7 14.8 0.049 13.4 2.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Dicty_REP PF05086.12 CEP17513.1 - 0.51 8.3 14.4 0.6 8.0 14.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LMBR1 PF04791.16 CEP17513.1 - 0.59 9.0 9.3 0.68 8.8 9.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC106 PF15794.5 CEP17513.1 - 0.62 9.7 15.3 0.89 9.2 15.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Band_3_cyto PF07565.13 CEP17513.1 - 1.1 9.0 13.2 1.4 8.7 13.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RasGAP_C PF03836.15 CEP17513.1 - 1.1 9.4 17.0 2.8 8.1 17.0 1.6 1 1 0 1 1 1 0 RasGAP C-terminus ALMT PF11744.8 CEP17513.1 - 1.6 7.5 13.0 1.9 7.2 13.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 CEP17513.1 - 1.8 7.1 16.1 2.2 6.8 16.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMF_TATA_bd PF12325.8 CEP17513.1 - 2.1 8.6 15.6 2e+02 2.2 15.6 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CHD5 PF04420.14 CEP17513.1 - 2.4 8.0 12.1 10 5.9 0.3 2.2 2 0 0 2 2 2 0 CHD5-like protein Zip PF02535.22 CEP17513.1 - 2.9 7.0 5.5 3 7.0 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rabaptin PF03528.15 CEP17513.1 - 5.2 5.7 17.7 4.4 5.9 13.5 1.9 1 1 1 2 2 2 0 Rabaptin RR_TM4-6 PF06459.12 CEP17513.1 - 9 6.0 14.9 11 5.7 14.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3294 PF07957.11 CEP17514.1 - 0.0048 16.7 0.4 0.0052 16.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF4298 PF14131.6 CEP17514.1 - 0.038 13.9 0.6 0.21 11.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Cg6151-P PF10233.9 CEP17515.1 - 6e-12 45.9 13.4 7.7e-12 45.5 4.8 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein CG6151-P PRA1 PF03208.19 CEP17515.1 - 0.012 15.2 3.6 0.032 13.9 0.6 2.0 2 0 0 2 2 2 0 PRA1 family protein DUF4149 PF13664.6 CEP17515.1 - 0.079 13.3 3.9 0.23 11.8 3.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Atthog PF18800.1 CEP17515.1 - 0.14 12.1 5.8 0.074 12.9 4.1 1.5 1 1 0 1 1 1 0 Attenuator of Hedgehog DUF1430 PF07242.11 CEP17515.1 - 5 7.5 11.1 3.6 7.9 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) Myb_DNA-binding PF00249.31 CEP17516.1 - 1.8e-20 72.8 0.5 2.3e-07 30.9 0.2 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP17516.1 - 1.3e-09 38.2 10.4 1.4e-05 25.3 0.7 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEP17516.1 - 7.3e-06 25.8 16.6 0.0066 16.3 5.7 4.3 3 0 0 3 3 3 2 Myb DNA-binding like SUIM_assoc PF16619.5 CEP17516.1 - 8.5 6.5 42.6 0.14 12.3 7.6 5.0 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CEP17517.1 - 1.4e-72 244.2 0.0 1.9e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17517.1 - 6.7e-32 110.8 0.0 6.3e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CEP17517.1 - 2.5e-08 33.6 1.0 0.054 12.8 0.0 3.1 2 1 0 3 3 3 3 Kinase-like APH PF01636.23 CEP17517.1 - 0.0033 17.4 0.0 1.2 9.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP17517.1 - 0.018 13.9 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CEP17517.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tropomyosin_1 PF12718.7 CEP17518.1 - 6.4e-18 65.3 28.7 4.9e-10 39.7 13.6 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 CEP17518.1 - 6.9e-08 32.2 23.6 7.5e-08 32.0 23.6 1.1 1 0 0 1 1 1 1 Tropomyosin ATG16 PF08614.11 CEP17518.1 - 2.3e-05 24.7 19.1 3.1e-05 24.3 19.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 CEP17518.1 - 3.3e-05 23.8 28.5 0.013 15.5 8.5 2.2 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 CEP17518.1 - 0.00016 22.2 13.3 0.00016 22.2 13.3 1.8 1 1 1 2 2 2 1 Fez1 AAA_13 PF13166.6 CEP17518.1 - 0.00027 19.7 15.7 0.00031 19.5 15.7 1.0 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.12 CEP17518.1 - 0.00063 19.8 2.7 0.00079 19.5 2.3 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 CEP17518.1 - 0.0011 19.0 6.2 0.0011 19.0 6.2 2.2 1 1 1 2 2 2 1 Laminin Domain II Filament PF00038.21 CEP17518.1 - 0.0012 18.5 17.7 0.0016 18.1 17.2 1.4 1 1 0 1 1 1 1 Intermediate filament protein NPV_P10 PF05531.12 CEP17518.1 - 0.0015 19.0 2.6 0.0015 19.0 2.6 2.5 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein GAS PF13851.6 CEP17518.1 - 0.002 17.5 24.6 0.047 13.0 24.6 2.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 CEP17518.1 - 0.0025 17.5 20.8 0.11 12.2 4.8 2.0 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 CEP17518.1 - 0.0026 16.7 24.1 0.04 12.8 24.1 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 CEP17518.1 - 0.0028 17.3 6.6 0.0028 17.3 6.6 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EzrA PF06160.12 CEP17518.1 - 0.0039 15.4 21.0 0.011 14.0 21.0 1.6 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 CEP17518.1 - 0.0047 17.3 16.9 0.02 15.3 2.6 3.2 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) FH2 PF02181.23 CEP17518.1 - 0.005 16.0 7.9 0.005 16.0 7.9 1.8 1 1 1 2 2 2 1 Formin Homology 2 Domain ERM PF00769.19 CEP17518.1 - 0.0063 16.4 22.5 0.0079 16.0 11.2 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family HOOK PF05622.12 CEP17518.1 - 0.007 14.6 19.6 0.0082 14.4 19.6 1.0 1 0 0 1 1 1 1 HOOK protein Gp58 PF07902.11 CEP17518.1 - 0.0071 14.7 2.0 0.0076 14.6 2.0 1.0 1 0 0 1 1 1 1 gp58-like protein UPF0242 PF06785.11 CEP17518.1 - 0.0088 16.2 13.1 0.0088 16.2 13.1 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 CEP17518.1 - 0.011 15.8 7.5 0.011 15.8 7.5 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 XhlA PF10779.9 CEP17518.1 - 0.012 15.8 23.9 0.13 12.4 9.9 3.1 1 1 2 3 3 3 0 Haemolysin XhlA DUF4315 PF14193.6 CEP17518.1 - 0.015 15.3 9.7 0.015 15.3 9.7 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4315) CENP-F_leu_zip PF10473.9 CEP17518.1 - 0.015 15.3 15.2 0.015 15.3 15.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 CEP17518.1 - 0.015 14.6 16.2 0.14 11.4 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 CEP17518.1 - 0.017 15.4 5.8 0.13 12.6 5.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FPP PF05911.11 CEP17518.1 - 0.018 13.3 21.6 0.027 12.7 21.6 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF16 PF01519.16 CEP17518.1 - 0.018 15.5 17.0 2.3 8.8 17.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3584 PF12128.8 CEP17518.1 - 0.021 12.4 16.7 0.026 12.1 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 CEP17518.1 - 0.022 15.1 16.5 0.046 14.0 8.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 CEP17518.1 - 0.024 14.7 23.1 0.25 11.4 12.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein T3SSipB PF16535.5 CEP17518.1 - 0.024 15.1 2.9 0.024 15.1 2.9 2.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB MCPsignal PF00015.21 CEP17518.1 - 0.025 14.4 0.8 0.025 14.4 0.8 1.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF812 PF05667.11 CEP17518.1 - 0.026 13.4 20.9 0.072 12.0 20.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CALCOCO1 PF07888.11 CEP17518.1 - 0.027 13.4 19.1 0.03 13.2 19.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Peptidase_M27 PF01742.17 CEP17518.1 - 0.03 13.4 4.2 0.035 13.2 4.2 1.0 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF1664 PF07889.12 CEP17518.1 - 0.037 14.1 12.3 0.044 13.8 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 CEP17518.1 - 0.042 14.6 16.3 0.088 13.6 14.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF1943 PF09172.11 CEP17518.1 - 0.043 13.1 4.3 0.048 12.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Spc29 PF17082.5 CEP17518.1 - 0.043 13.7 10.5 0.21 11.4 10.5 1.9 1 1 0 1 1 1 0 Spindle Pole Component 29 Caskin-tail PF16632.5 CEP17518.1 - 0.043 14.2 0.8 0.043 14.2 0.8 2.6 1 1 2 3 3 2 0 C-terminal region of Caskin DUF745 PF05335.13 CEP17518.1 - 0.054 13.2 11.3 0.016 14.9 6.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) ADIP PF11559.8 CEP17518.1 - 0.055 13.6 21.3 0.03 14.4 11.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 CEP17518.1 - 0.056 13.7 22.1 0.077 13.2 22.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2009 PF09418.10 CEP17518.1 - 0.059 12.4 5.0 0.053 12.6 4.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) Fib_alpha PF08702.10 CEP17518.1 - 0.061 13.5 14.2 0.46 10.6 5.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sugarporin_N PF11471.8 CEP17518.1 - 0.07 13.1 7.0 0.71 9.9 0.1 2.4 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension NDT80_PhoG PF05224.12 CEP17518.1 - 0.075 13.2 3.2 0.085 13.1 3.2 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family FTO_CTD PF12934.7 CEP17518.1 - 0.076 12.8 4.4 0.045 13.5 2.4 1.6 1 1 0 1 1 1 0 FTO C-terminal domain DHR10 PF18595.1 CEP17518.1 - 0.1 12.6 24.8 0.97 9.5 11.1 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF2730 PF10805.8 CEP17518.1 - 0.1 12.7 12.9 0.067 13.3 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PI_PP_I PF18363.1 CEP17518.1 - 0.11 12.7 1.7 0.22 11.7 1.7 1.8 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain DUF489 PF04356.12 CEP17518.1 - 0.11 12.4 5.9 0.32 11.0 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) ApoO PF09769.9 CEP17518.1 - 0.12 12.4 2.2 0.18 11.7 0.6 2.0 1 1 1 2 2 2 0 Apolipoprotein O MAD PF05557.13 CEP17518.1 - 0.13 10.6 19.6 0.18 10.2 19.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4200 PF13863.6 CEP17518.1 - 0.13 12.7 25.8 0.18 12.2 19.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TolA_bind_tri PF16331.5 CEP17518.1 - 0.15 12.1 12.2 0.79 9.8 2.0 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation VGPC1_C PF16799.5 CEP17518.1 - 0.17 11.9 11.6 0.37 10.8 3.3 3.2 2 1 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Angiomotin_C PF12240.8 CEP17518.1 - 0.17 11.4 13.4 0.099 12.2 5.0 2.1 1 1 1 2 2 2 0 Angiomotin C terminal IFT57 PF10498.9 CEP17518.1 - 0.19 10.6 17.4 0.013 14.5 9.1 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 CEP17518.1 - 0.2 11.9 8.0 15 5.9 0.3 3.4 2 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF724 PF05266.14 CEP17518.1 - 0.2 11.5 20.4 0.061 13.2 10.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YscO-like PF16789.5 CEP17518.1 - 0.2 11.7 20.1 0.3 11.1 20.1 1.3 1 0 0 1 1 1 0 YscO-like protein BRE1 PF08647.11 CEP17518.1 - 0.2 11.7 21.9 0.16 12.1 11.7 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMCO5 PF14992.6 CEP17518.1 - 0.21 11.1 19.7 0.27 10.8 19.7 1.1 1 0 0 1 1 1 0 TMCO5 family DUF4407 PF14362.6 CEP17518.1 - 0.22 10.9 13.2 0.28 10.5 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 CEP17518.1 - 0.22 11.9 18.6 0.68 10.3 1.7 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF773 PF05600.12 CEP17518.1 - 0.22 10.2 13.9 0.027 13.2 8.9 1.7 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Lectin_N PF03954.14 CEP17518.1 - 0.24 11.1 12.3 0.22 11.2 3.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Exonuc_VII_L PF02601.15 CEP17518.1 - 0.26 10.8 10.6 0.3 10.6 10.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 CEP17518.1 - 0.29 11.4 24.3 0.65 10.3 10.1 3.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Uso1_p115_C PF04871.13 CEP17518.1 - 0.3 11.5 24.9 0.056 13.8 14.1 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region THOC7 PF05615.13 CEP17518.1 - 0.33 11.2 15.8 0.46 10.8 15.8 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4795 PF16043.5 CEP17518.1 - 0.36 10.4 23.6 0.1 12.2 13.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) COG2 PF06148.11 CEP17518.1 - 0.37 10.9 11.4 0.083 13.0 5.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vac_Fusion PF02346.16 CEP17518.1 - 0.38 10.4 8.9 7.2 6.3 0.4 3.2 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF2203 PF09969.9 CEP17518.1 - 0.38 11.5 13.8 0.48 11.2 4.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Bacillus_HBL PF05791.11 CEP17518.1 - 0.4 10.5 15.0 0.08 12.8 5.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Occludin_ELL PF07303.13 CEP17518.1 - 0.41 11.4 16.1 2.1 9.1 5.2 2.4 1 1 1 2 2 2 0 Occludin homology domain APG6_N PF17675.1 CEP17518.1 - 0.48 11.0 29.5 6 7.4 29.5 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region FliD_C PF07195.12 CEP17518.1 - 0.6 9.5 9.7 2 7.8 9.7 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TMPIT PF07851.13 CEP17518.1 - 0.66 9.2 16.5 0.14 11.4 9.1 1.8 1 1 1 2 2 2 0 TMPIT-like protein V-SNARE PF05008.15 CEP17518.1 - 0.79 10.1 19.6 0.18 12.2 11.7 2.6 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3552 PF12072.8 CEP17518.1 - 0.81 9.1 21.6 1.8 8.0 21.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4201 PF13870.6 CEP17518.1 - 0.83 9.4 22.7 0.16 11.7 11.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PspA_IM30 PF04012.12 CEP17518.1 - 1 8.9 19.4 0.56 9.7 9.1 2.8 1 1 1 2 2 2 0 PspA/IM30 family Prominin PF05478.11 CEP17518.1 - 1.2 7.0 9.6 1.3 6.9 9.6 1.0 1 0 0 1 1 1 0 Prominin Noelin-1 PF12308.8 CEP17518.1 - 1.2 9.1 6.7 1.1 9.3 2.9 2.2 1 1 2 3 3 2 0 Neurogenesis glycoprotein DUF4806 PF16064.5 CEP17518.1 - 1.4 9.3 5.5 1.2 9.5 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) Golgin_A5 PF09787.9 CEP17518.1 - 1.5 8.2 19.8 1.7 8.1 19.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 CEP17518.1 - 1.9 8.1 12.0 2.7 7.5 12.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TSNAXIP1_N PF15739.5 CEP17518.1 - 1.9 8.9 16.4 0.57 10.6 6.2 2.5 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Allexi_40kDa PF05549.11 CEP17518.1 - 1.9 8.0 13.2 0.77 9.2 3.0 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Phage_GP20 PF06810.11 CEP17518.1 - 1.9 8.3 24.7 4.9 6.9 13.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 OmpH PF03938.14 CEP17518.1 - 2 8.8 22.1 0.17 12.2 12.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HemX PF04375.14 CEP17518.1 - 2 7.6 14.4 12 5.1 14.4 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4349 PF14257.6 CEP17518.1 - 2 7.8 8.5 5.1 6.5 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Cep57_CLD PF14073.6 CEP17518.1 - 2.2 8.3 24.8 0.67 10.0 13.8 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 TMF_TATA_bd PF12325.8 CEP17518.1 - 2.2 8.5 22.7 6.6 7.0 21.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 CEP17518.1 - 2.4 7.5 25.3 5.7 6.3 25.3 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FliD_N PF02465.18 CEP17518.1 - 2.5 8.9 8.7 22 5.8 8.7 2.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus KELK PF15796.5 CEP17518.1 - 2.6 8.6 23.7 2.3 8.7 12.8 2.9 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF641 PF04859.12 CEP17518.1 - 2.8 8.3 17.1 2 8.8 3.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SOAR PF16533.5 CEP17518.1 - 3 7.9 11.8 2.5e+02 1.7 11.8 2.9 1 1 0 1 1 1 0 STIM1 Orai1-activating region Seryl_tRNA_N PF02403.22 CEP17518.1 - 3 8.1 21.5 3.4 7.9 8.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rootletin PF15035.6 CEP17518.1 - 3.1 7.8 18.3 0.92 9.5 8.6 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.20 CEP17518.1 - 3.2 7.8 28.7 6.5 6.8 2.4 3.3 1 1 2 3 3 3 0 Prefoldin subunit FapA PF03961.13 CEP17518.1 - 3.2 6.2 21.0 0.25 9.9 11.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A BST2 PF16716.5 CEP17518.1 - 3.8 8.2 20.9 3.8 8.1 8.7 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 CEP17518.1 - 4.6 5.0 15.6 19 3.0 15.6 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-ZPR1 PF03367.13 CEP17518.1 - 4.7 7.1 10.4 0.5 10.2 5.4 1.7 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Med4 PF10018.9 CEP17518.1 - 6.3 6.4 21.0 23 4.6 8.5 2.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4094 PF13334.6 CEP17518.1 - 6.4 7.3 13.2 8.9 6.8 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 CEP17518.1 - 6.4 7.5 14.1 4 8.1 3.4 2.9 1 1 3 4 4 3 0 SlyX HIP1_clath_bdg PF16515.5 CEP17518.1 - 7 7.3 20.0 7.5 7.2 5.6 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 CEP17518.1 - 7.1 7.3 14.0 3.7e+02 1.7 14.0 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Prefoldin PF02996.17 CEP17518.1 - 8.2 6.4 22.0 5.7 6.9 1.5 3.3 1 1 1 3 3 3 0 Prefoldin subunit CENP-Q PF13094.6 CEP17518.1 - 9.3 6.4 25.4 2.6 8.2 11.3 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HSP70 PF00012.20 CEP17518.1 - 9.9 4.2 16.7 11 4.1 16.7 1.0 1 0 0 1 1 1 0 Hsp70 protein RSN1_7TM PF02714.15 CEP17519.1 - 4.9e-56 190.1 28.1 4.9e-56 190.1 28.1 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CEP17519.1 - 8.8e-26 91.2 1.0 1.6e-25 90.3 1.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CEP17519.1 - 5.2e-18 65.3 2.6 5.2e-18 65.3 2.6 5.0 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport F-box-like PF12937.7 CEP17520.1 - 4.4e-05 23.3 2.3 7.2e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 CEP17520.1 - 0.079 12.7 6.0 3.3 7.5 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat Pyr_redox_2 PF07992.14 CEP17521.1 - 4.1e-33 114.9 0.1 7.5e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP17521.1 - 6.8e-17 61.8 0.0 3.2e-11 43.6 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 CEP17521.1 - 1.1e-10 41.7 0.2 2.3e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 CEP17521.1 - 2.8e-09 37.1 0.0 0.029 14.0 0.0 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP17521.1 - 1.3e-07 31.2 0.0 1.8e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP17521.1 - 2.6e-07 30.7 0.0 0.025 14.8 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CEP17521.1 - 7.6e-05 22.7 0.1 16 5.5 0.0 4.4 2 2 1 4 4 4 0 FAD-NAD(P)-binding RGS-like PF09128.11 CEP17521.1 - 0.00044 20.0 0.1 0.00078 19.2 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain TrkA_N PF02254.18 CEP17521.1 - 0.00077 19.7 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.19 CEP17521.1 - 0.00095 18.5 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CEP17521.1 - 0.0012 18.0 0.0 0.5 9.3 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 CEP17521.1 - 0.0083 16.4 0.1 5.4 7.3 0.0 2.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 CEP17521.1 - 0.011 14.9 0.4 1.4 8.0 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 CEP17521.1 - 0.015 14.8 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 CEP17521.1 - 0.016 14.1 0.1 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 CEP17521.1 - 0.021 14.1 0.0 7.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CEP17521.1 - 0.071 13.6 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 CEP17521.1 - 0.073 11.8 0.0 5.5 5.6 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.22 CEP17521.1 - 0.08 12.0 0.1 5.3 6.0 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Thi4 PF01946.17 CEP17521.1 - 0.12 11.6 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Tim44 PF04280.15 CEP17522.1 - 4.2e-36 124.2 0.1 4.2e-36 124.2 0.1 2.1 3 0 0 3 3 3 1 Tim44-like domain SUIM_assoc PF16619.5 CEP17522.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.2 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Arc_PepC PF06819.11 CEP17522.1 - 0.17 12.0 10.3 8.5 6.5 0.2 3.8 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain DUF4398 PF14346.6 CEP17522.1 - 0.23 12.1 6.6 9.5 6.9 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DUF4041 PF13250.6 CEP17522.1 - 0.48 10.4 3.2 1.8 8.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Neur_chan_memb PF02932.16 CEP17522.1 - 1.8 8.6 4.3 3.5 7.6 4.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CHAD PF05235.14 CEP17522.1 - 2.9 7.8 6.9 6.6 6.6 0.1 2.2 1 1 0 2 2 2 0 CHAD domain DUF327 PF03885.13 CEP17522.1 - 3.2 7.7 10.2 1.7 8.6 6.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF327) DUF2175 PF09943.9 CEP17522.1 - 4.2 7.7 9.1 0.45 10.8 1.7 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) UEV PF05743.13 CEP17523.1 - 9e-26 90.1 0.6 4.5e-25 87.9 0.6 2.1 1 1 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CEP17523.1 - 1.7e-14 53.5 0.4 1.2e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Vps23 core domain Ribosomal_S4e PF00900.20 CEP17523.1 - 0.085 12.8 0.3 0.67 9.9 0.0 2.5 3 0 0 3 3 3 0 Ribosomal family S4e PIN_12 PF16289.5 CEP17523.1 - 0.64 10.5 9.0 0.068 13.7 2.8 2.3 2 0 0 2 2 2 0 PIN domain Mucin-like PF16058.5 CEP17524.1 - 0.007 16.4 2.8 0.012 15.6 2.8 1.4 1 0 0 1 1 1 1 Mucin-like DCAF15_WD40 PF14939.6 CEP17524.1 - 3.3 7.3 8.0 96 2.5 8.0 2.6 1 1 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat MAP65_ASE1 PF03999.12 CEP17524.1 - 8.7 4.9 10.7 19 3.8 10.6 1.6 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ABC_tran PF00005.27 CEP17525.1 - 2.8e-45 154.2 0.5 8.8e-22 78.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CEP17525.1 - 7.6e-22 77.1 7.0 5.8e-21 74.3 2.6 3.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 CEP17525.1 - 1.3e-16 61.3 8.4 0.0021 18.0 0.5 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CEP17525.1 - 4.4e-09 36.1 1.4 0.019 14.4 0.3 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEP17525.1 - 2.2e-08 33.7 0.1 0.0063 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 CEP17525.1 - 2.4e-07 31.0 3.0 0.019 15.0 0.1 3.8 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 CEP17525.1 - 1.1e-06 29.0 0.1 0.0067 16.7 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CEP17525.1 - 2.8e-06 27.5 0.1 0.13 12.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 CEP17525.1 - 3e-06 27.2 3.5 0.036 13.8 0.0 3.6 3 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 CEP17525.1 - 3.6e-06 27.3 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CEP17525.1 - 6.6e-06 26.6 0.0 0.048 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CEP17525.1 - 9.2e-06 26.3 7.6 0.051 14.1 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 CEP17525.1 - 1.6e-05 25.4 0.2 0.033 14.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 CEP17525.1 - 2.3e-05 24.2 0.5 0.17 11.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CEP17525.1 - 3.2e-05 23.9 0.9 0.12 12.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CEP17525.1 - 7.6e-05 22.8 0.0 0.36 10.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 CEP17525.1 - 8.6e-05 22.6 0.0 1.6 8.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 CEP17525.1 - 0.00014 21.9 0.0 0.82 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_27 PF13514.6 CEP17525.1 - 0.00025 20.7 0.0 0.29 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CEP17525.1 - 0.0005 20.4 0.1 1.7 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_30 PF13604.6 CEP17525.1 - 0.00059 19.6 0.0 0.18 11.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 CEP17525.1 - 0.00084 19.8 0.2 0.34 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEP17525.1 - 0.0013 18.4 0.0 1.3 8.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain EIIA-man PF03610.16 CEP17525.1 - 0.0025 18.0 1.1 0.029 14.6 0.3 2.7 3 0 0 3 3 2 1 PTS system fructose IIA component DUF87 PF01935.17 CEP17525.1 - 0.0028 17.8 0.5 4.5 7.3 0.0 3.1 2 1 0 2 2 2 0 Helicase HerA, central domain VirE PF05272.11 CEP17525.1 - 0.0033 17.2 0.1 0.59 9.8 0.0 2.9 3 0 0 3 3 3 1 Virulence-associated protein E MeaB PF03308.16 CEP17525.1 - 0.004 16.2 0.0 0.77 8.7 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 CEP17525.1 - 0.0066 16.7 0.1 1.2 9.4 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 CEP17525.1 - 0.0066 16.9 0.4 0.67 10.4 0.1 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CEP17525.1 - 0.0083 15.3 0.0 1.3 8.1 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain TsaE PF02367.17 CEP17525.1 - 0.016 15.2 0.2 0.94 9.5 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CEP17525.1 - 0.017 14.7 1.1 6.3 6.4 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 CEP17525.1 - 0.02 14.9 0.0 4.7 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 CEP17525.1 - 0.02 14.4 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 CEP17525.1 - 0.021 14.6 0.2 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CEP17525.1 - 0.032 13.5 0.2 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CEP17525.1 - 0.035 14.3 0.0 3.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 CEP17525.1 - 0.04 13.8 0.0 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 CEP17525.1 - 0.04 13.1 1.1 7.3 5.6 0.0 2.8 2 2 1 3 3 3 0 G-protein alpha subunit MukB PF04310.12 CEP17525.1 - 0.044 13.6 0.0 9.5 5.9 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal FtsK_SpoIIIE PF01580.18 CEP17525.1 - 0.045 13.1 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 CEP17525.1 - 0.084 12.5 0.0 7.1 6.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CEP17525.1 - 0.088 12.3 0.0 2.8 7.4 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CEP17525.1 - 0.088 12.5 0.0 1.5 8.6 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein Septin PF00735.18 CEP17525.1 - 0.099 11.9 0.3 12 5.1 0.0 2.5 3 0 0 3 3 2 0 Septin PduV-EutP PF10662.9 CEP17525.1 - 0.1 12.4 0.1 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 CEP17525.1 - 0.1 12.5 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain MarR_2 PF12802.7 CEP17525.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 MarR family T2SSE PF00437.20 CEP17525.1 - 0.14 11.2 0.0 5.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Pkinase PF00069.25 CEP17527.1 - 6e-69 232.3 0.0 7.9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17527.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP17527.1 - 1.9e-05 23.8 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP17527.1 - 3.4e-05 23.3 0.1 0.0001 21.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP17527.1 - 0.00067 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEP17527.1 - 0.019 14.6 0.2 0.035 13.7 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CEP17527.1 - 0.038 13.3 0.0 0.2 10.9 0.0 1.9 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 CEP17527.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YqeY PF09424.10 CEP17528.1 - 7.6e-37 126.6 2.0 8.9e-37 126.3 2.0 1.0 1 0 0 1 1 1 1 Yqey-like protein Fanconi_A_N PF15865.5 CEP17528.1 - 0.017 14.5 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus RabGAP-TBC PF00566.18 CEP17529.1 - 1.4e-44 152.3 3.0 3.3e-44 151.1 3.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CEP17529.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 0 Rab-binding domain (RBD) MBOAT PF03062.19 CEP17530.1 - 2.4e-35 122.5 29.7 1.3e-34 120.2 29.6 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CEP17530.1 - 0.00013 22.1 2.2 0.00046 20.4 2.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family FAD_binding_7 PF03441.14 CEP17531.1 - 2.7e-63 213.1 0.2 5.5e-63 212.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase LMWPc PF01451.21 CEP17531.1 - 1.3e-44 152.0 0.0 2.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DNA_photolyase PF00875.18 CEP17531.1 - 3.7e-19 69.3 0.0 1.2e-18 67.7 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase COQ9 PF08511.11 CEP17532.1 - 0.0084 15.9 0.1 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 COQ9 DiSB-ORF2_chro PF16506.5 CEP17532.1 - 0.082 12.9 0.1 3.5 7.7 0.0 2.7 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses RED_C PF07807.11 CEP17532.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RED-like protein C-terminal region EF-hand_1 PF00036.32 CEP17533.1 - 9.8e-14 49.8 8.7 3.1e-05 23.2 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CEP17533.1 - 5.7e-12 44.6 8.0 0.00022 20.9 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CEP17533.1 - 7.5e-12 45.5 4.1 3.2e-06 27.5 0.5 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CEP17533.1 - 2e-09 36.5 2.0 0.0013 18.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CEP17533.1 - 1.1e-08 34.7 8.7 3.2e-06 26.9 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_11 PF08976.11 CEP17533.1 - 0.0044 17.9 0.1 0.017 16.0 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 CEP17533.1 - 0.09 13.1 0.1 17 5.8 0.0 2.8 2 2 0 2 2 2 0 EF-hand domain Cation_ATPase_C PF00689.21 CEP17534.1 - 2.1e-45 154.7 12.8 2.1e-45 154.7 12.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEP17534.1 - 1e-34 119.7 0.7 1e-34 119.7 0.7 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEP17534.1 - 2.3e-21 75.7 0.0 4.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP17534.1 - 3.7e-17 63.3 0.0 1.5e-16 61.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP17534.1 - 3.1e-09 36.4 0.1 1.1e-06 28.2 0.0 2.8 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP17534.1 - 7.1e-05 22.7 0.3 0.0015 18.4 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UPF0061 PF02696.14 CEP17535.1 - 6.9e-133 443.8 0.0 8.9e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF445 PF04286.12 CEP17535.1 - 0.28 10.9 1.4 0.41 10.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) gag-asp_proteas PF13975.6 CEP17537.1 - 0.0052 17.3 0.1 0.019 15.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP17537.1 - 0.048 14.3 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 CEP17538.1 - 2.2e-10 40.4 0.3 7.4e-10 38.7 0.3 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP17539.1 - 8.3e-17 61.0 0.2 1.4e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP17539.1 - 3.5e-06 27.2 0.0 6.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain LPD14 PF18827.1 CEP17541.1 - 0.093 13.0 0.2 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 14 NusA_N PF08529.11 CEP17543.1 - 0.011 16.1 0.1 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 NusA N-terminal domain PAS PF00989.25 CEP17545.1 - 8.6e-12 45.1 0.1 2.7e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 CEP17545.1 - 3.4e-10 40.1 0.0 8.7e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 CEP17545.1 - 2.2e-07 31.0 0.0 9.7e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 CEP17545.1 - 5.1e-07 29.9 0.0 0.00094 19.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CEP17545.1 - 8.6e-06 25.9 0.0 0.004 17.4 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 CEP17545.1 - 4.8e-05 24.0 0.0 0.056 14.1 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_12 PF18095.1 CEP17545.1 - 0.053 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain G6PD_C PF02781.16 CEP17546.1 - 3.3e-113 377.7 0.1 1.9e-112 375.2 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CEP17546.1 - 2.3e-58 197.7 0.4 7.9e-58 196.0 0.1 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Imm5 PF14423.6 CEP17546.1 - 0.12 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein Imm5 Mitofilin PF09731.9 CEP17547.1 - 9.5e-88 295.6 33.6 1.2e-78 265.5 30.5 2.3 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Nsp1_C PF05064.13 CEP17547.1 - 0.02 14.7 0.4 0.02 14.7 0.4 3.1 4 0 0 4 4 4 0 Nsp1-like C-terminal region RasGAP_C PF03836.15 CEP17547.1 - 0.86 9.8 9.9 7.9 6.6 5.9 3.4 2 1 0 2 2 2 0 RasGAP C-terminus MFS_1_like PF12832.7 CEP17548.1 - 1.6e-14 53.6 3.3 2.1e-14 53.2 3.3 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CEP17548.1 - 0.023 13.6 15.3 0.66 8.8 13.5 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 CEP17549.1 - 6.9e-66 222.1 0.0 8.3e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CEP17549.1 - 1.5e-05 24.1 0.2 0.00015 20.8 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 CEP17549.1 - 2.7e-05 23.2 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase AXE1 PF05448.12 CEP17549.1 - 0.00023 19.9 0.0 0.00041 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 CEP17549.1 - 0.024 13.6 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1899 PF08953.11 CEP17549.1 - 0.026 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Chlorophyllase PF07224.11 CEP17549.1 - 0.038 13.0 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase PAF-AH_p_II PF03403.13 CEP17549.1 - 0.095 11.2 0.1 0.23 9.9 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 CEP17549.1 - 0.18 11.4 0.2 4.7 6.8 0.2 2.2 1 1 0 1 1 1 0 Putative esterase LSM PF01423.22 CEP17550.1 - 1.1e-16 60.3 0.0 1.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain KTSC PF13619.6 CEP17550.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 KTSC domain SM-ATX PF14438.6 CEP17550.1 - 0.027 14.6 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FoP_duplication PF13865.6 CEP17550.1 - 5 7.7 18.5 7.1 7.3 18.5 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HSF_DNA-bind PF00447.17 CEP17551.1 - 6.3e-33 113.3 2.5 6.3e-33 113.3 2.5 3.0 3 2 0 3 3 3 1 HSF-type DNA-binding ATG16 PF08614.11 CEP17551.1 - 0.0047 17.2 1.1 0.0047 17.2 1.1 3.1 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) LMBR1 PF04791.16 CEP17551.1 - 0.054 12.4 7.6 0.074 12.0 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cob_adeno_trans PF01923.18 CEP17551.1 - 1.2 9.3 3.4 0.45 10.6 0.6 1.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase E1-E2_ATPase PF00122.20 CEP17552.1 - 2.1e-33 115.4 4.8 1.1e-23 83.7 0.0 4.1 4 1 1 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 CEP17552.1 - 3.9e-24 86.1 3.8 3.4e-20 73.3 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP17552.1 - 1.2e-19 70.2 0.1 2.3e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CEP17552.1 - 8.2e-12 45.2 0.1 8.2e-12 45.2 0.1 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CEP17552.1 - 4.6e-11 42.3 0.7 8e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP17552.1 - 1.3e-06 28.4 0.6 0.00014 21.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP17552.1 - 0.013 15.9 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase IL7 PF01415.16 CEP17553.1 - 0.089 12.8 1.9 0.93 9.5 0.1 2.6 2 0 0 2 2 2 0 Interleukin 7/9 family zf-C2H2 PF00096.26 CEP17554.1 - 1.4e-09 37.9 13.3 7.7e-05 22.9 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP17554.1 - 2.1e-06 28.0 10.6 0.0037 18.0 1.0 3.3 3 0 0 3 3 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP17554.1 - 1.5e-05 25.2 0.4 1.5e-05 25.2 0.4 4.0 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEP17554.1 - 0.00015 21.7 5.1 0.0023 17.9 0.8 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP17554.1 - 0.00069 19.8 1.0 0.023 15.0 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Gp-FAR-1 PF05823.12 CEP17554.1 - 0.028 14.8 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-BED PF02892.15 CEP17554.1 - 0.16 12.0 2.9 2.9 8.0 0.2 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.6 CEP17554.1 - 0.23 11.4 1.6 2.3 8.2 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 CEP17554.1 - 0.66 10.5 4.7 1.2 9.6 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 CEP17554.1 - 1.2 9.1 6.4 0.48 10.4 1.0 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 CEP17554.1 - 8.9 6.2 10.1 0.5 10.2 1.3 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain VTC PF09359.10 CEP17555.1 - 9.5e-103 343.4 0.2 1.3e-102 342.9 0.2 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CEP17555.1 - 5.2e-16 59.5 13.2 9e-06 25.8 0.0 4.0 3 2 2 5 5 5 3 SPX domain DUF202 PF02656.15 CEP17555.1 - 1e-14 54.7 0.1 2.1e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) ECH_1 PF00378.20 CEP17556.1 - 3.4e-23 82.3 0.0 4.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP17556.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CEP17556.1 - 0.012 15.6 0.0 0.88 9.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 bZIP_1 PF00170.21 CEP17557.1 - 5.1e-07 29.7 24.1 0.0003 20.8 10.9 2.7 1 1 1 2 2 2 2 bZIP transcription factor Atg14 PF10186.9 CEP17557.1 - 0.0033 16.6 3.9 0.0044 16.1 3.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_2 PF07716.15 CEP17557.1 - 0.034 14.2 24.2 0.13 12.4 10.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper YabA PF06156.13 CEP17557.1 - 0.13 12.9 7.2 0.12 13.0 4.8 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Chibby PF14645.6 CEP17557.1 - 0.57 10.6 7.6 1.4 9.3 7.6 1.7 1 1 0 1 1 1 0 Chibby family DDRGK PF09756.9 CEP17557.1 - 1.1 8.8 13.1 1.8 8.1 13.1 1.2 1 0 0 1 1 1 0 DDRGK domain ZapB PF06005.12 CEP17557.1 - 7.4 7.1 16.9 0.48 10.9 6.0 2.7 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CEP17557.1 - 8 6.3 13.8 6 6.7 10.8 2.2 1 1 1 2 2 2 0 Septum formation initiator Ytp1 PF10355.9 CEP17558.1 - 2e-16 60.0 4.4 2.6e-15 56.4 4.4 2.7 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.20 CEP17558.1 - 0.00079 19.1 11.1 0.0046 16.6 0.1 3.1 2 1 0 2 2 2 1 Prokaryotic cytochrome b561 Rieske PF00355.26 CEP17559.1 - 8.3e-12 44.9 0.0 1.8e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CEP17559.1 - 6.6e-11 42.5 0.6 1.9e-10 41.1 0.6 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region SUKH-4 PF14435.6 CEP17559.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein PIF1 PF05970.14 CEP17560.1 - 2.1e-22 79.8 0.0 3.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF3336 PF11815.8 CEP17561.1 - 4.8e-44 149.4 5.6 1e-43 148.3 5.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEP17561.1 - 5.6e-16 59.3 0.1 5.6e-15 56.1 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase OrfB_Zn_ribbon PF07282.11 CEP17562.1 - 0.0019 18.1 2.5 0.047 13.6 2.5 2.4 1 1 0 1 1 1 1 Putative transposase DNA-binding domain Nt_Gln_amidase PF09764.9 CEP17564.1 - 0.0047 16.6 0.1 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 N-terminal glutamine amidase Asp-B-Hydro_N PF05279.11 CEP17564.1 - 0.086 12.9 5.7 0.15 12.1 5.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4820 PF16091.5 CEP17564.1 - 0.21 10.9 4.4 0.42 10.0 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CdiI_2 PF18593.1 CEP17564.1 - 0.35 11.5 2.4 0.67 10.7 0.2 2.7 3 0 0 3 3 3 0 CdiI immunity protein DUF4065 PF13274.6 CEP17564.1 - 4.3 8.3 6.5 0.88 10.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DDE_3 PF13358.6 CEP17565.1 - 1.4e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.7 CEP17566.1 - 2.6e-21 76.0 0.6 1.4e-10 41.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP17566.1 - 2.1e-18 64.5 0.2 0.00098 19.4 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 CEP17566.1 - 1.1e-16 61.0 0.2 1.4e-08 35.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CEP17566.1 - 1.8e-13 50.3 0.7 0.00072 19.9 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CEP17566.1 - 9.7e-10 38.5 3.5 0.0016 18.7 0.0 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) GrpE PF01025.19 CEP17566.1 - 0.015 14.9 2.3 0.039 13.6 2.3 1.7 1 0 0 1 1 1 0 GrpE FRB_dom PF08771.11 CEP17566.1 - 0.044 14.2 1.9 0.1 13.0 1.9 1.6 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Mu-like_Com PF10122.9 CEP17568.1 - 0.066 12.7 0.3 0.14 11.6 0.3 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Holin_BhlA PF10960.8 CEP17568.1 - 0.21 11.6 3.0 4.6 7.3 0.4 3.1 3 0 0 3 3 3 0 BhlA holin family CEP63 PF17045.5 CEP17569.1 - 0.0059 16.5 18.6 0.0059 16.5 18.6 3.5 3 1 0 3 3 3 2 Centrosomal protein of 63 kDa DUF4881 PF16222.5 CEP17569.1 - 0.041 13.7 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) Vac_Fusion PF02346.16 CEP17569.1 - 4.8 6.9 7.7 1.5 8.5 0.1 3.8 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Endonuclease_NS PF01223.23 CEP17570.1 - 7.8e-66 222.1 0.3 9.3e-66 221.9 0.3 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-TRAF PF02176.18 CEP17571.1 - 8.4e-15 55.2 27.8 9.6e-10 39.0 5.1 3.8 1 1 3 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 CEP17571.1 - 1.6e-07 31.1 10.6 1.6e-07 31.1 10.6 3.4 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 CEP17571.1 - 2.7e-07 31.0 28.4 5.9e-05 23.5 0.7 4.1 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-RING_2 PF13639.6 CEP17571.1 - 1.1e-06 28.9 10.7 1.1e-06 28.9 10.7 3.8 2 1 1 3 3 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP17571.1 - 1.7e-06 27.9 12.9 7.4e-06 25.9 12.9 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CEP17571.1 - 2.7e-06 27.1 7.1 2.7e-06 27.1 7.1 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP17571.1 - 9.4e-06 25.4 11.7 9.4e-06 25.4 11.7 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP17571.1 - 0.00026 21.2 9.2 0.00026 21.2 9.2 4.0 3 2 0 3 3 2 1 RING-H2 zinc finger domain Sina PF03145.16 CEP17571.1 - 0.00028 20.9 24.9 0.013 15.4 4.2 3.8 2 1 2 4 4 3 2 Seven in absentia protein family zf-RING_5 PF14634.6 CEP17571.1 - 0.0003 20.7 10.4 0.0003 20.7 10.4 3.3 2 2 0 2 2 1 1 zinc-RING finger domain U-box PF04564.15 CEP17571.1 - 0.00068 19.8 0.6 0.03 14.5 0.0 3.0 2 1 1 3 3 3 1 U-box domain zf-ACC PF17848.1 CEP17571.1 - 0.00069 19.6 10.4 0.0084 16.2 0.6 4.0 3 0 0 3 3 3 1 Acetyl-coA carboxylase zinc finger domain zf-Nse PF11789.8 CEP17571.1 - 0.00092 19.0 14.0 0.0015 18.3 5.8 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CEP17571.1 - 0.0019 18.3 11.8 0.0019 18.3 11.8 2.8 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CEP17571.1 - 0.0023 17.7 8.6 0.0023 17.7 8.6 3.3 3 1 1 4 4 2 1 Prokaryotic RING finger family 4 HALZ PF02183.18 CEP17571.1 - 0.0097 16.1 11.9 0.035 14.3 0.6 3.7 3 1 0 3 3 3 1 Homeobox associated leucine zipper DASH_Dad3 PF08656.10 CEP17571.1 - 0.23 11.5 5.0 0.066 13.3 1.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 CENP-H PF05837.12 CEP17571.1 - 0.26 11.7 11.5 0.11 13.0 1.8 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Topoisom_I_N PF02919.15 CEP17571.1 - 0.3 10.6 1.7 0.26 10.8 0.3 1.6 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Uso1_p115_C PF04871.13 CEP17571.1 - 1.6 9.1 9.4 1.2 9.5 1.2 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 CEP17571.1 - 4.5 7.7 12.1 10 6.5 12.1 1.7 1 1 0 1 1 1 0 Fez1 zf-RING_6 PF14835.6 CEP17571.1 - 5.8 6.9 9.2 1 9.3 4.8 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein PAH PF02671.21 CEP17572.1 - 2.3e-48 162.1 2.2 4e-17 62.1 1.9 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CEP17572.1 - 1.9e-40 136.9 1.6 1.3e-39 134.2 0.0 3.0 3 0 0 3 3 3 1 Sin3 family co-repressor Sin3a_C PF16879.5 CEP17572.1 - 5.5e-11 42.7 0.1 5.5e-11 42.7 0.1 4.3 4 1 0 4 4 3 1 C-terminal domain of Sin3a protein YL1 PF05764.13 CEP17572.1 - 5.5e-05 23.4 20.8 5.5e-05 23.4 20.8 2.9 3 1 0 3 3 3 1 YL1 nuclear protein SDA1 PF05285.12 CEP17572.1 - 0.00082 18.9 23.1 0.00082 18.9 23.1 2.2 2 0 0 2 2 2 1 SDA1 BSP_II PF05432.11 CEP17572.1 - 0.0032 17.2 18.5 0.0032 17.2 18.5 2.2 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 CEP17572.1 - 0.041 12.0 27.3 0.099 10.7 27.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CEP17572.1 - 0.043 12.1 29.3 0.083 11.2 29.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CEP17572.1 - 0.22 9.7 41.4 0.012 13.8 30.1 3.0 3 0 0 3 3 3 0 Nop14-like family Hid1 PF12722.7 CEP17572.1 - 0.42 8.7 12.6 0.91 7.6 12.6 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 CEP17572.1 - 2.6 7.3 48.9 0.81 9.0 41.3 2.8 2 1 0 2 2 2 0 BUD22 GREB1 PF15782.5 CEP17572.1 - 6.8 3.7 13.6 12 2.9 13.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sin3a_C PF16879.5 CEP17573.1 - 1.1e-51 176.3 0.6 1.1e-51 176.3 0.6 1.5 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein EMG1 PF03587.14 CEP17574.1 - 4.9e-78 261.3 0.3 5.9e-78 261.0 0.3 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PP2C_C PF07830.13 CEP17574.1 - 0.12 12.8 0.2 0.33 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ank_2 PF12796.7 CEP17575.1 - 2e-06 28.3 0.0 2.4e-05 24.8 0.0 2.4 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEP17575.1 - 3.8e-05 23.9 0.0 0.009 16.3 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP17575.1 - 0.00037 21.0 0.6 0.055 14.1 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Luteo_Vpg PF01659.16 CEP17576.1 - 0.14 12.5 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Fasciclin PF02469.22 CEP17577.1 - 3e-17 63.0 3.3 1e-09 38.7 0.2 2.4 2 0 0 2 2 2 2 Fasciclin domain Tudor_FRX1 PF18336.1 CEP17578.1 - 0.16 11.9 0.5 1.9 8.5 0.6 2.4 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain PTH2 PF01981.16 CEP17580.1 - 5.6e-17 62.1 0.2 6.4e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BRCT PF00533.26 CEP17580.1 - 0.055 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain IL34 PF15036.6 CEP17580.1 - 0.084 12.9 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin 34 TRM PF02005.16 CEP17581.1 - 9e-133 443.1 0.1 1.1e-132 442.7 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CEP17581.1 - 0.00035 20.4 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein GlutR_dimer PF00745.20 CEP17581.1 - 0.016 15.6 0.3 0.035 14.6 0.3 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain MTS PF05175.14 CEP17581.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PX PF00787.24 CEP17582.1 - 1.4e-27 95.9 0.0 1.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 PX domain zf-CCCH_2 PF14608.6 CEP17583.1 - 0.00011 22.6 2.0 0.00011 22.6 2.0 2.5 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CEP17583.1 - 0.00021 21.2 3.2 0.00021 21.2 3.2 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CEP17583.1 - 0.0013 18.5 0.6 0.0013 18.5 0.6 2.3 3 0 0 3 3 3 1 CCCH-type zinc finger Methyltransf_32 PF13679.6 CEP17583.1 - 0.023 14.7 0.0 0.067 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CEP17583.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MoCF_biosynth PF00994.24 CEP17584.1 - 4.1e-20 71.9 0.0 1.3e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Probable molybdopterin binding domain Nucleotid_trans PF03407.16 CEP17585.1 - 2.7e-25 89.6 1.0 3.9e-25 89.1 1.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PH_9 PF15410.6 CEP17586.1 - 4.1e-34 117.5 1.3 1.5e-33 115.7 1.3 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 CEP17586.1 - 4.3e-30 104.8 0.1 1.1e-29 103.5 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CEP17586.1 - 1.2e-07 32.2 0.1 9e-06 26.2 0.1 2.5 1 1 0 1 1 1 1 PH domain DUF1079 PF06435.11 CEP17586.1 - 2.2 8.6 4.8 7.1 7.0 4.8 1.9 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) Peptidase_S8 PF00082.22 CEP17587.1 - 3.5e-41 141.4 7.6 3.5e-41 141.4 7.6 1.6 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 CEP17587.1 - 8.5e-13 49.0 0.4 2e-12 47.8 0.4 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 CEP17587.1 - 1.5e-07 31.4 0.1 3.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 PA domain UDPGP PF01704.18 CEP17588.1 - 2.5e-56 191.1 0.0 3.3e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CEP17588.1 - 0.15 12.4 0.2 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Arrestin_C PF02752.22 CEP17589.1 - 1.3e-08 35.4 0.1 3.4e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP17589.1 - 3.6e-08 33.6 0.0 5.5e-07 29.7 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP17589.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Toxin_16 PF07945.11 CEP17590.1 - 0.081 12.8 0.4 0.081 12.8 0.4 2.3 2 0 0 2 2 2 0 Janus-atracotoxin AMP-binding PF00501.28 CEP17591.1 - 7.7e-20 70.9 0.3 1.1e-15 57.2 0.2 3.0 2 1 0 2 2 2 2 AMP-binding enzyme Glyco_hydro_47 PF01532.20 CEP17592.1 - 6.1e-155 516.6 0.6 7.4e-155 516.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SAPS PF04499.15 CEP17594.1 - 5.2e-06 25.5 1.2 7.3e-06 25.0 1.2 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PRP1_N PF06424.12 CEP17594.1 - 0.37 11.2 27.2 1.5 9.3 17.7 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SID-1_RNA_chan PF13965.6 CEP17594.1 - 1.4 7.3 2.3 0.59 8.5 0.1 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 CEP17594.1 - 7.7 6.5 10.0 15 5.5 10.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_2 PF07716.15 CEP17595.1 - 4.2e-06 26.7 5.3 4.2e-06 26.7 5.3 3.2 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP17595.1 - 5.7e-05 23.1 5.5 5.7e-05 23.1 5.5 1.7 1 1 0 1 1 1 1 bZIP transcription factor RteC PF09357.10 CEP17595.1 - 0.00071 19.3 1.1 0.0011 18.7 1.1 1.4 1 0 0 1 1 1 1 RteC protein bZIP_Maf PF03131.17 CEP17595.1 - 0.0074 16.8 4.6 0.0074 16.8 4.6 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor Macoilin PF09726.9 CEP17595.1 - 0.019 13.6 18.1 0.025 13.2 18.1 1.2 1 0 0 1 1 1 0 Macoilin family Csm1_N PF18504.1 CEP17595.1 - 0.04 14.2 1.4 0.04 14.2 1.4 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF5101 PF17031.5 CEP17595.1 - 0.07 13.2 0.1 0.07 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) YabA PF06156.13 CEP17595.1 - 3.6 8.3 13.1 4.7 7.9 12.2 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TCO89 PF10452.9 CEP17596.1 - 1.1e-14 54.3 0.8 1.1e-14 54.3 0.8 2.1 1 1 1 2 2 2 1 TORC1 subunit TCO89 Bud13 PF09736.9 CEP17596.1 - 0.15 12.4 8.0 3.4 8.0 1.9 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex WD40 PF00400.32 CEP17597.1 - 5e-08 33.5 3.6 0.026 15.4 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17597.1 - 2.1e-07 31.1 0.1 0.0079 16.5 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP17597.1 - 4e-05 22.7 0.9 0.056 12.4 0.1 2.8 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PBECR2 PF18810.1 CEP17597.1 - 0.13 12.5 0.1 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Kinesin PF00225.23 CEP17598.1 - 3.1e-93 312.4 3.0 4.2e-93 311.9 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP17598.1 - 1.6e-16 60.6 0.8 7.5e-16 58.4 0.0 2.6 4 0 0 4 4 4 1 Microtubule binding SAM_2 PF07647.17 CEP17598.1 - 0.00086 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP17598.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L35Ae PF01247.18 CEP17599.1 - 1.6e-42 143.5 0.9 1.8e-42 143.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CEP17599.1 - 0.0014 18.8 0.1 0.28 11.4 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Bcr-Abl_Oligo PF09036.10 CEP17599.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HTH_39 PF14090.6 CEP17600.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain GSHPx PF00255.19 CEP17601.1 - 7e-42 141.4 0.2 1e-41 140.9 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CEP17601.1 - 4.6e-06 26.6 0.4 1.3e-05 25.1 0.4 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP17601.1 - 0.00044 20.0 0.3 0.0029 17.3 0.3 2.1 1 1 0 1 1 1 1 Redoxin Lipase_3 PF01764.25 CEP17602.1 - 7.7e-13 48.5 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 CEP17602.1 - 9.9e-08 32.2 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain zf-RVT PF13966.6 CEP17604.1 - 4.7e-06 27.2 2.0 1.1e-05 26.1 2.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase F-box PF00646.33 CEP17605.1 - 1.9e-07 30.7 0.0 6.6e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CEP17605.1 - 3.3e-05 23.7 0.0 8.3e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CEP17605.1 - 0.0064 16.9 6.3 5.6 7.5 0.0 5.9 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) Recep_L_domain PF01030.24 CEP17606.1 - 1.9e-08 34.4 5.8 0.015 15.4 0.3 5.0 1 1 3 4 4 4 3 Receptor L domain LRR_4 PF12799.7 CEP17606.1 - 0.044 14.2 14.4 0.06 13.8 0.0 5.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF3971 PF13116.6 CEP17606.1 - 0.053 13.1 6.6 0.68 9.4 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function F-box-like PF12937.7 CEP17607.1 - 0.0029 17.4 0.1 0.012 15.5 0.1 2.2 1 0 0 1 1 1 1 F-box-like Na_sulph_symp PF00939.19 CEP17608.1 - 1.6e-35 123.1 26.8 2.2e-35 122.6 26.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 CEP17608.1 - 1.4e-34 120.7 8.6 2.9e-22 80.1 6.1 2.6 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 CEP17608.1 - 7.6e-27 94.3 53.1 3.1e-23 82.4 31.1 2.2 1 1 1 2 2 2 2 Citrate transporter RicinB_lectin_2 PF14200.6 CEP17609.1 - 1.4e-05 25.7 0.6 0.13 13.0 0.0 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like MAPKK1_Int PF08923.10 CEP17610.1 - 2.4e-28 98.3 0.3 2.8e-28 98.1 0.3 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting OrfB_Zn_ribbon PF07282.11 CEP17611.1 - 4.6e-08 32.9 0.2 1.1e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Proteasome PF00227.26 CEP17612.1 - 1.3e-47 161.7 0.1 1.6e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Rad60-SLD PF11976.8 CEP17613.1 - 7.4e-24 83.4 0.0 9e-24 83.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CEP17613.1 - 4e-12 45.7 0.0 5.1e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SCO1-SenC PF02630.14 CEP17614.1 - 6e-45 152.4 0.0 9.2e-45 151.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CEP17614.1 - 0.00072 19.8 0.0 0.0023 18.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CEP17614.1 - 0.0089 15.9 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family RE_HaeII PF09554.10 CEP17614.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 HaeII restriction endonuclease TMF_DNA_bd PF12329.8 CEP17615.1 - 0.28 11.2 2.1 2.8 8.0 0.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FMN_red PF03358.15 CEP17616.1 - 0.00028 20.6 0.0 0.003 17.3 0.0 2.2 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Nup84_Nup100 PF04121.13 CEP17617.1 - 4.4e-53 180.5 20.2 6.3e-43 146.9 7.7 2.7 1 1 1 3 3 3 2 Nuclear pore protein 84 / 107 CorA PF01544.18 CEP17618.1 - 4.4e-46 157.5 11.1 1.1e-28 100.4 0.8 2.6 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Metallophos PF00149.28 CEP17620.1 - 1.1e-17 65.3 1.1 1.7e-17 64.6 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 CEP17620.1 - 1.4e-11 44.8 0.5 3.5e-11 43.5 0.5 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 CEP17620.1 - 0.0011 19.8 0.1 0.0051 17.6 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Adaptin_N PF01602.20 CEP17621.1 - 5.2e-119 398.2 8.5 8e-119 397.5 8.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEP17621.1 - 4.3e-18 65.9 5.5 2.3e-12 47.2 0.0 3.8 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP17621.1 - 1.3e-06 28.1 2.6 4.6 7.8 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 CEP17621.1 - 4e-05 23.9 0.2 0.37 11.2 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats AP4E_app_platf PF14807.6 CEP17621.1 - 0.0038 17.6 0.3 0.011 16.0 0.3 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform VPS9 PF02204.18 CEP17622.1 - 1.1e-32 112.4 0.5 2.9e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CEP17622.1 - 1.9e-09 37.7 0.6 1.9e-09 37.7 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) ACBP PF00887.19 CEP17623.1 - 9.7e-23 80.2 0.3 1.1e-22 80.0 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_M24 PF00557.24 CEP17624.1 - 2.8e-55 187.3 0.0 3.5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CEP17624.1 - 8.6e-14 51.3 0.0 4.5e-13 49.0 0.0 2.0 1 1 1 2 2 2 1 Aminopeptidase P, N-terminal domain Dus PF01207.17 CEP17625.1 - 3.2e-59 200.5 0.0 5.1e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CEP17625.1 - 0.022 14.6 1.5 0.022 14.6 1.5 3.2 4 0 0 4 4 4 0 CCCH-type zinc finger NAD_Gly3P_dh_C PF07479.14 CEP17626.1 - 2.1e-49 167.5 0.1 3.4e-49 166.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CEP17626.1 - 3.3e-49 166.9 0.0 6.2e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RET_CLD4 PF17813.1 CEP17627.1 - 0.1 12.9 2.5 0.59 10.4 0.2 2.5 2 0 0 2 2 2 0 RET Cadherin like domain 4 SH3_1 PF00018.28 CEP17628.1 - 2.8e-28 97.3 0.0 1.5e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CEP17628.1 - 3.5e-16 58.8 0.0 4e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CEP17628.1 - 4.5e-14 51.9 0.0 2.2e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 CEP17628.1 - 1.9e-08 34.2 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 CEP17628.1 - 0.00025 20.9 0.1 0.00059 19.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain SHMT PF00464.19 CEP17630.1 - 2.3e-199 662.0 0.7 2.3e-197 655.4 0.7 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 CEP17630.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L27A PF00828.19 CEP17631.1 - 4.2e-41 140.6 0.2 1.1e-40 139.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NNMT_PNMT_TEMT PF01234.17 CEP17631.1 - 0.05 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF21 PF01595.20 CEP17632.1 - 1.5e-33 116.0 0.6 4e-33 114.6 0.5 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CEP17632.1 - 1.9e-06 28.2 0.3 0.09 13.2 0.1 2.7 2 0 0 2 2 2 2 CBS domain UPF0270 PF06794.12 CEP17632.1 - 0.097 12.8 0.6 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) BTB PF00651.31 CEP17633.1 - 6e-06 26.5 0.0 6.1e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 BTB/POZ domain CsgA PF17334.2 CEP17633.1 - 0.023 15.4 0.1 0.21 12.4 0.0 2.4 2 0 0 2 2 2 0 Minor curli fiber component A RNA_helicase PF00910.22 CEP17634.1 - 0.0019 18.5 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 CEP17634.1 - 0.003 16.8 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 CEP17634.1 - 0.0034 17.3 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CEP17634.1 - 0.0051 16.9 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Smg8_Smg9 PF10220.9 CEP17634.1 - 0.008 14.5 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Smg8_Smg9 MeaB PF03308.16 CEP17634.1 - 0.01 14.8 0.0 0.044 12.8 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CEP17634.1 - 0.014 15.9 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pterin_4a PF01329.19 CEP17634.1 - 0.02 15.0 0.6 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Roc PF08477.13 CEP17634.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP17634.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.6 CEP17634.1 - 0.096 12.4 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CEP17634.1 - 0.17 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CEP17634.1 - 0.17 12.2 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sas10_Utp3 PF04000.15 CEP17635.1 - 3.9e-18 65.9 1.6 1.6e-17 63.9 1.6 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CHD5 PF04420.14 CEP17635.1 - 0.8 9.6 4.6 0.34 10.7 0.8 2.2 2 0 0 2 2 2 0 CHD5-like protein Kelch_5 PF13854.6 CEP17636.1 - 4.2e-28 96.8 3.0 3.7e-06 26.8 0.5 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CEP17636.1 - 1.9e-25 88.6 6.3 7.3e-06 25.9 0.0 6.9 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP17636.1 - 8.7e-24 83.0 3.3 0.00011 22.4 0.1 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 CEP17636.1 - 1.1e-23 82.5 0.7 1.8e-07 30.6 0.0 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CEP17636.1 - 5.7e-19 67.9 0.6 3.7e-05 23.9 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP17636.1 - 5.7e-13 48.3 1.6 0.00019 21.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif THUMP PF02926.17 CEP17639.1 - 7.4e-16 58.6 0.0 1.6e-15 57.5 0.0 1.6 1 1 1 2 2 2 1 THUMP domain Peptidase_M76 PF09768.9 CEP17640.1 - 1.4e-70 236.6 6.9 2.1e-70 235.9 6.9 1.3 1 0 0 1 1 1 1 Peptidase M76 family DEAD PF00270.29 CEP17640.1 - 8.9e-49 165.6 0.0 8.2e-48 162.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17640.1 - 9.6e-32 109.6 0.0 4.1e-31 107.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP17640.1 - 0.0012 18.9 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CEP17640.1 - 0.015 14.1 0.0 0.22 10.3 0.0 2.3 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 TB2_DP1_HVA22 PF03134.19 CEP17641.1 - 1.3e-29 102.0 5.8 1.3e-29 102.0 5.8 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family GUCT PF08152.12 CEP17642.1 - 0.075 13.3 0.0 0.34 11.2 0.0 2.2 1 0 0 1 1 1 0 GUCT (NUC152) domain Pkinase PF00069.25 CEP17643.1 - 2.8e-43 148.2 0.0 1.6e-41 142.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CEP17643.1 - 1.9e-42 144.4 0.0 4.9e-42 143.1 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CEP17643.1 - 1.4e-24 86.8 0.0 1.6e-21 76.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP17643.1 - 0.00027 19.8 0.3 0.0039 16.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 CEP17643.1 - 0.00065 19.4 0.0 0.09 12.3 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 CEP17643.1 - 0.013 15.4 0.5 0.16 12.0 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.6 CEP17643.1 - 2.3 8.8 3.7 48 4.6 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Transcrip_reg PF01709.20 CEP17644.1 - 5.3e-72 242.1 11.9 7.3e-64 215.5 3.5 2.0 1 1 1 2 2 2 2 Transcriptional regulator HTH_15 PF12324.8 CEP17644.1 - 0.075 13.0 0.4 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Pkinase PF00069.25 CEP17645.1 - 3.1e-74 249.6 0.0 5.5e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17645.1 - 1.2e-37 129.7 0.0 2.3e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.22 CEP17645.1 - 2.5e-21 76.3 3.7 2.5e-21 76.3 3.7 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter APH PF01636.23 CEP17645.1 - 3.1e-05 24.0 0.2 0.27 11.1 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEP17645.1 - 0.0012 18.2 0.3 0.0024 17.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CEP17645.1 - 0.037 13.6 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CEP17645.1 - 0.042 13.2 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like DUF4203 PF13886.6 CEP17645.1 - 0.052 13.2 13.1 0.02 14.5 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) FA_desaturase PF00487.24 CEP17645.1 - 0.79 9.5 9.6 0.014 15.2 1.4 2.4 4 0 0 4 4 4 0 Fatty acid desaturase WWE PF02825.20 CEP17647.1 - 0.0047 17.5 0.6 0.0054 17.3 0.6 1.1 1 0 0 1 1 1 1 WWE domain RTP1_C1 PF10363.9 CEP17650.1 - 4.1e-32 110.7 2.3 9.2e-32 109.6 0.0 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CEP17650.1 - 2.5e-11 43.0 0.9 8.1e-11 41.4 0.9 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 CEP17650.1 - 3.2e-05 24.2 1.2 0.38 11.2 0.0 4.1 4 1 0 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CEP17650.1 - 0.0045 17.6 0.4 6 7.5 0.0 3.5 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region UNC80 PF15778.5 CEP17650.1 - 0.009 15.6 0.0 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 Cation channel complex component UNC80 RIX1 PF08167.12 CEP17650.1 - 0.11 12.2 8.9 0.031 14.0 0.8 3.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis SF-assemblin PF06705.11 CEP17650.1 - 0.3 10.4 3.9 1.2 8.4 2.8 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin DNA_topoisoIV PF00521.20 CEP17651.1 - 1.6e-113 379.9 0.0 2.9e-113 379.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CEP17651.1 - 1.5e-46 157.8 1.1 7.4e-46 155.6 1.1 2.3 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CEP17651.1 - 2.1e-25 89.2 0.1 4.9e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CEP17651.1 - 1.3e-14 54.6 0.0 3.2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CEP17651.1 - 1e-07 32.1 0.0 4.2e-07 30.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain DUF4809 PF16067.5 CEP17651.1 - 2.4 8.3 4.5 11 6.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4809) Ndc1_Nup PF09531.10 CEP17651.1 - 9.3 4.8 10.9 15 4.1 10.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RVT_1 PF00078.27 CEP17652.1 - 1.7e-26 93.2 0.0 5.3e-26 91.5 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP17652.1 - 0.00093 19.9 0.1 0.0025 18.5 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase AMP-binding PF00501.28 CEP17653.1 - 1.5e-97 326.9 0.0 1.9e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP17653.1 - 9e-22 77.9 0.0 2.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CEP17653.1 - 5.1e-19 67.9 2.2 3.5e-18 65.2 0.4 2.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Pkinase PF00069.25 CEP17654.1 - 2.6e-70 236.8 0.0 3.5e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17654.1 - 8.4e-34 117.0 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CEP17654.1 - 2e-05 23.7 0.2 7.1e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP17654.1 - 0.014 15.3 0.9 0.034 14.0 0.7 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CEP17654.1 - 0.092 12.4 0.2 0.67 9.5 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CEP17654.1 - 0.11 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FAM60A PF15396.6 CEP17654.1 - 1.7 8.6 5.9 2.5 8.0 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Na_H_Exchanger PF00999.21 CEP17655.1 - 7.7e-59 199.4 45.6 1.1e-58 198.8 45.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DHHC PF01529.20 CEP17656.1 - 7.1e-38 129.7 11.3 7.1e-38 129.7 11.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.21 CEP17656.1 - 0.18 12.0 6.2 0.48 10.6 6.2 1.8 1 0 0 1 1 1 0 FYVE zinc finger Tim17 PF02466.19 CEP17657.1 - 6.8e-24 84.4 8.0 9.6e-24 83.9 8.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Spt20 PF12090.8 CEP17658.1 - 0.0032 17.1 8.1 0.0032 17.1 8.1 1.6 2 0 0 2 2 2 1 Spt20 family DUF3246 PF11596.8 CEP17658.1 - 0.073 12.5 0.7 0.11 11.9 0.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Prok-TraM PF09228.10 CEP17658.1 - 0.15 12.4 6.8 0.4 11.1 6.8 1.6 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM PRIMA1 PF16101.5 CEP17658.1 - 0.17 11.9 1.4 0.73 9.9 0.3 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FAM176 PF14851.6 CEP17658.1 - 0.3 10.7 7.5 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 FAM176 family TFIIA PF03153.13 CEP17658.1 - 0.5 10.3 21.6 0.05 13.6 6.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CEP17658.1 - 0.61 11.1 8.9 0.21 12.6 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3417 PF11897.8 CEP17658.1 - 0.81 10.2 5.4 1.5 9.3 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Presenilin PF01080.17 CEP17658.1 - 1.1 8.0 5.4 1.4 7.6 5.4 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CEP17658.1 - 1.2 9.3 6.4 0.64 10.2 2.1 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RXT2_N PF08595.11 CEP17658.1 - 1.6 8.8 12.9 1.7 8.6 2.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 CEP17658.1 - 1.8 9.3 12.2 5 7.8 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Afi1 PF07792.12 CEP17658.1 - 2.7 8.5 15.4 1.9 9.0 5.7 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PTPRCAP PF15713.5 CEP17658.1 - 4.1 7.7 12.0 4.5 7.6 0.5 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pex14_N PF04695.13 CEP17658.1 - 9.2 6.9 14.0 0.83 10.3 7.7 2.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CSD PF00313.22 CEP17659.1 - 1.2e-20 73.2 0.4 2e-20 72.4 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CEP17659.1 - 0.089 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain PH_4 PF15404.6 CEP17660.1 - 1.6e-12 47.6 13.1 1.7e-05 24.7 2.1 4.8 3 1 1 4 4 4 2 Pleckstrin homology domain PH PF00169.29 CEP17660.1 - 7.5e-10 39.3 13.9 0.022 15.2 0.0 5.5 3 2 1 4 4 4 3 PH domain PH_6 PF15406.6 CEP17660.1 - 0.12 12.6 0.3 3 8.2 0.0 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain Hydrolase_3 PF08282.12 CEP17660.1 - 0.35 10.6 1.8 0.91 9.2 1.6 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase KASH_CCD PF14662.6 CEP17661.1 - 0.0077 16.1 13.7 0.2 11.5 0.5 2.6 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF5314 PF17241.2 CEP17661.1 - 0.0085 15.8 2.7 0.0085 15.8 2.7 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5314) YabA PF06156.13 CEP17661.1 - 0.023 15.4 9.4 1.8 9.3 3.7 2.9 2 0 0 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 CEP17661.1 - 0.056 13.8 9.4 0.74 10.2 0.2 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family TPR_12 PF13424.6 CEP17661.1 - 0.1 12.9 0.4 0.1 12.9 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HMMR_N PF15905.5 CEP17661.1 - 0.3 10.5 20.3 0.045 13.2 14.9 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Phage_GP20 PF06810.11 CEP17661.1 - 0.42 10.4 14.3 0.21 11.4 6.7 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 Shugoshin_N PF07558.11 CEP17661.1 - 0.56 10.1 6.5 3 7.8 1.4 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.12 CEP17661.1 - 2.5 8.2 21.6 8.7 6.4 16.3 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.9 CEP17661.1 - 2.6 8.0 21.2 0.22 11.4 7.8 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain DUF737 PF05300.11 CEP17661.1 - 7.1 6.9 18.8 35 4.7 19.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF737) RabGAP-TBC PF00566.18 CEP17662.1 - 3.3e-33 115.1 0.3 3.3e-33 115.1 0.3 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TMEM154 PF15102.6 CEP17663.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.5 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 CEP17663.1 - 0.0046 17.8 0.0 0.013 16.3 0.0 1.8 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 CEP17663.1 - 0.005 17.0 0.7 0.005 17.0 0.7 1.8 2 0 0 2 2 2 1 Podoplanin YajC PF02699.15 CEP17663.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit CcmD PF04995.14 CEP17663.1 - 0.052 13.6 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Amnionless PF14828.6 CEP17663.1 - 0.057 12.2 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Herpes_gE PF02480.16 CEP17663.1 - 0.058 12.1 0.2 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E CbtA PF09490.10 CEP17663.1 - 0.078 12.7 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Yip1 PF04893.17 CEP17663.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.20 CEP17663.1 - 0.14 12.1 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2615 PF11027.8 CEP17663.1 - 0.17 12.0 0.5 4.5 7.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) DUF515 PF04415.12 CEP17663.1 - 1.2 7.5 4.8 1.8 6.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) HhH-GPD PF00730.25 CEP17664.1 - 2e-19 70.1 0.0 4.4e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEP17664.1 - 1.7e-06 27.6 0.0 4.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CEP17664.1 - 0.034 14.5 5.1 0.064 13.6 5.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Put_Phosphatase PF06888.12 CEP17665.1 - 2.2e-42 145.1 0.4 2.6e-42 144.8 0.4 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 CEP17665.1 - 6.4e-05 23.4 0.1 0.0011 19.4 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP17665.1 - 0.082 13.2 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CEP17665.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) HLH PF00010.26 CEP17666.1 - 2.4e-09 37.0 1.0 2.4e-09 37.0 1.0 2.3 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 CEP17666.1 - 0.0028 17.7 4.3 0.0028 17.7 4.3 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CEP17666.1 - 0.0071 16.0 9.5 0.012 15.2 9.5 1.3 1 0 0 1 1 1 1 Spt20 family Med25_VWA PF11265.8 CEP17666.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Androgen_recep PF02166.16 CEP17666.1 - 0.094 11.5 5.0 0.15 10.9 5.0 1.3 1 0 0 1 1 1 0 Androgen receptor CBP4 PF07960.11 CEP17666.1 - 4.8 7.0 10.2 1.8 8.4 0.8 2.7 2 1 1 3 3 3 0 CBP4 Glycos_transf_1 PF00534.20 CEP17667.1 - 2.2e-14 53.4 0.0 4.8e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CEP17667.1 - 3.7e-14 53.0 0.1 8.3e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 CEP17667.1 - 8.4e-13 48.9 0.0 6.3e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEP17667.1 - 0.0015 18.6 0.0 0.011 15.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CEP17667.1 - 0.0049 17.3 0.0 0.041 14.3 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Sld5 PF05916.11 CEP17668.1 - 1.9e-22 79.8 1.5 2.8e-22 79.2 1.5 1.3 1 0 0 1 1 1 1 GINS complex protein TPR_19 PF14559.6 CEP17669.1 - 2e-18 66.7 11.0 4.9e-06 27.0 0.1 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 CEP17669.1 - 1.8e-17 62.3 17.8 2.8e-06 26.9 0.0 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17669.1 - 8.7e-17 60.4 11.3 0.0027 18.4 0.2 8.7 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP17669.1 - 1.1e-15 56.4 20.1 1.7e-05 24.6 0.0 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17669.1 - 5.6e-15 54.2 18.4 1.2e-05 25.1 0.0 8.8 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CEP17669.1 - 1.5e-13 50.1 1.8 1.4 9.5 0.2 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEP17669.1 - 5.7e-11 42.9 6.7 0.00016 22.3 0.1 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP17669.1 - 1.9e-09 37.2 4.7 0.031 14.9 0.2 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP17669.1 - 5.2e-09 36.2 6.3 0.062 13.5 0.0 5.9 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEP17669.1 - 2.6e-08 33.4 12.5 0.0013 18.3 0.0 6.7 7 1 1 8 8 7 3 TPR repeat TPR_7 PF13176.6 CEP17669.1 - 5.4e-06 26.1 11.7 0.052 13.6 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEP17669.1 - 1.2e-05 25.3 7.6 1.3 9.3 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP17669.1 - 1.6e-05 25.2 16.9 3 8.7 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat ANAPC8 PF04049.13 CEP17669.1 - 0.00018 21.6 0.9 0.00067 19.7 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_12 PF13424.6 CEP17669.1 - 0.00025 21.3 19.7 0.00045 20.5 0.2 7.6 7 2 0 7 7 7 1 Tetratricopeptide repeat DUF3682 PF12446.8 CEP17669.1 - 0.00036 21.0 10.8 0.00074 20.0 10.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) TPR_20 PF14561.6 CEP17669.1 - 0.0012 19.1 3.6 0.71 10.2 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.8 CEP17669.1 - 0.0013 17.8 0.1 0.96 8.3 0.3 2.9 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 CEP17669.1 - 0.0019 17.6 1.5 0.0019 17.6 1.5 5.4 5 1 1 6 6 6 2 MalT-like TPR region TPR_21 PF09976.9 CEP17669.1 - 0.026 14.2 4.5 0.059 13.1 0.0 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 CEP17669.1 - 0.03 13.5 0.0 0.03 13.5 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CEP17669.1 - 2.4 8.6 5.6 7.5 7.0 0.1 3.5 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 CEP17669.1 - 5.5 7.0 13.0 11 6.1 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ARID PF01388.21 CEP17670.1 - 4.8e-20 72.0 0.0 1.3e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FOXP-CC PF16159.5 CEP17670.1 - 2.4e-06 28.1 6.4 0.0055 17.3 0.9 2.8 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 CEP17670.1 - 0.78 10.3 6.1 1.9 9.1 0.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.25 CEP17671.1 - 4.3e-53 180.4 0.4 2.2e-52 178.0 0.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17671.1 - 2.3e-22 79.6 0.0 4.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP17671.1 - 0.00054 19.9 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CEP17671.1 - 0.0035 17.0 1.7 0.04 13.5 1.7 2.3 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 CEP17671.1 - 0.12 11.7 2.4 0.41 10.0 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 CEP17671.1 - 0.73 9.8 42.7 0.29 11.1 9.7 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Choline_kinase PF01633.20 CEP17671.1 - 2.6 7.6 8.7 0.22 11.1 0.1 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase zf-C2H2 PF00096.26 CEP17672.1 - 2.5e-11 43.4 24.6 2e-05 24.8 0.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP17672.1 - 4.3e-05 23.7 1.2 4.3e-05 23.7 1.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain Zap1_zf2 PF18217.1 CEP17672.1 - 0.00013 21.8 3.7 0.00013 21.8 3.7 2.4 2 0 0 2 2 2 1 Zap1 zinc finger 2 zf-C2H2_4 PF13894.6 CEP17672.1 - 0.00018 22.0 21.3 0.0096 16.7 0.4 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger FOXP-CC PF16159.5 CEP17672.1 - 0.0012 19.4 0.1 0.0012 19.4 0.1 9.9 8 3 3 11 11 11 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CEP17672.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_ZIC PF18366.1 CEP17672.1 - 0.45 10.6 4.6 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 Zic proteins zinc finger domain C2 PF00168.30 CEP17674.1 - 1.3e-16 60.7 0.0 4.1e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 CEP17674.1 - 5.2e-16 59.2 7.4 2.3e-10 40.8 1.6 3.6 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 CEP17674.1 - 2.8e-08 32.8 1.8 1.3e-07 30.6 0.1 2.6 4 0 0 4 4 4 1 Plant family of unknown function (DUF810) TBCC_N PF16752.5 CEP17674.1 - 0.52 10.8 5.0 3.6 8.0 0.0 3.7 3 1 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Septin PF00735.18 CEP17675.1 - 4.1e-57 193.6 0.8 2.5e-39 135.2 0.1 2.4 2 1 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 CEP17675.1 - 0.0001 22.4 0.0 0.00022 21.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CEP17675.1 - 0.00039 20.9 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CEP17675.1 - 0.00059 19.4 0.1 0.04 13.4 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CEP17675.1 - 0.00089 19.4 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CEP17675.1 - 0.0013 18.7 0.1 0.0052 16.8 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CEP17675.1 - 0.0015 18.1 0.1 0.044 13.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 CEP17675.1 - 0.0016 18.5 1.1 0.13 12.3 0.0 2.8 3 0 0 3 3 3 1 Dynamin family NACHT PF05729.12 CEP17675.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CEP17675.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 CEP17675.1 - 0.031 13.5 0.2 0.083 12.0 0.2 1.6 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 CEP17675.1 - 0.036 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CEP17675.1 - 0.036 13.8 0.6 0.61 9.8 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CEP17675.1 - 0.083 12.7 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 CEP17675.1 - 0.09 12.5 0.3 4.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CEP17675.1 - 0.1 12.9 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_49 PF13896.6 CEP17676.1 - 5e-62 210.2 1.7 1.1e-51 176.2 1.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Mob1_phocein PF03637.17 CEP17677.1 - 2.2e-37 128.7 0.1 3e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family CRM1_C PF08767.11 CEP17678.1 - 2.6e-125 417.9 4.2 7.5e-125 416.4 0.0 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CEP17678.1 - 6.5e-34 117.2 10.4 2.6e-33 115.2 3.8 4.4 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 CEP17678.1 - 4.6e-30 103.5 2.5 1.1e-29 102.3 1.3 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CEP17678.1 - 3.4e-19 68.1 1.7 7.4e-19 67.0 1.7 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat CRM1_repeat_2 PF18784.1 CEP17678.1 - 1.3e-12 47.1 9.9 1.5e-12 47.0 1.3 3.7 2 1 1 3 3 3 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 CEP17678.1 - 4e-12 45.9 1.7 4e-12 45.9 1.7 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CEP17678.1 - 0.12 12.2 5.0 0.56 10.1 0.0 4.3 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 CEP17678.1 - 0.14 12.7 1.6 3.5 8.3 0.0 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Ral PF11058.8 CEP17678.1 - 0.23 11.1 3.6 0.21 11.2 0.8 2.3 2 0 0 2 2 2 0 Antirestriction protein Ral HLH PF00010.26 CEP17679.1 - 3e-11 43.1 0.1 7e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2486 PF10667.9 CEP17679.1 - 0.01 16.1 1.9 0.013 15.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) GIT_CC PF16559.5 CEP17679.1 - 0.039 13.8 2.0 0.43 10.5 0.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ndc1_Nup PF09531.10 CEP17680.1 - 2.1e-65 221.6 3.3 2.8e-65 221.2 3.3 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Glyco_transf_15 PF01793.16 CEP17680.1 - 3.2e-33 115.4 4.1 2.1e-26 93.0 2.3 2.3 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase TAN PF11640.8 CEP17680.1 - 0.026 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair RGS PF00615.19 CEP17681.1 - 1.7e-05 25.0 0.0 6.3e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain DHHC PF01529.20 CEP17681.1 - 0.025 14.7 2.1 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2892 PF11127.8 CEP17681.1 - 0.031 14.3 0.6 0.031 14.3 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) MRAP PF15183.6 CEP17681.1 - 0.043 13.8 1.2 0.089 12.7 1.2 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family RST PF12174.8 CEP17681.1 - 0.074 13.0 0.6 0.21 11.5 0.6 1.7 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Arm PF00514.23 CEP17682.1 - 9.6e-74 241.4 23.7 1.4e-12 47.2 0.1 10.6 11 0 0 11 11 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP17682.1 - 2.6e-18 66.2 12.9 0.00014 22.1 0.1 6.7 2 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 CEP17682.1 - 3e-18 65.9 22.4 0.00014 22.3 0.3 8.3 8 1 1 9 9 8 5 HEAT-like repeat Adaptin_N PF01602.20 CEP17682.1 - 8.9e-15 54.2 11.5 2.8e-11 42.7 1.2 2.3 1 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 CEP17682.1 - 9.8e-13 47.2 18.8 0.12 12.7 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat KAP PF05804.12 CEP17682.1 - 1.1e-11 43.6 3.2 2.6e-11 42.4 3.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 CEP17682.1 - 3.2e-11 43.2 8.8 2.8e-07 30.2 2.5 3.2 1 1 2 3 3 3 2 Armadillo-like V-ATPase_H_N PF03224.14 CEP17682.1 - 4.2e-07 29.6 5.2 0.0062 15.9 0.5 3.4 1 1 2 3 3 3 3 V-ATPase subunit H Cnd1 PF12717.7 CEP17682.1 - 8e-07 29.2 8.0 0.0088 16.1 1.2 4.8 2 2 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 CEP17682.1 - 4.5e-06 26.7 5.9 0.095 12.6 0.1 3.7 2 2 1 3 3 3 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 CEP17682.1 - 0.00013 22.1 9.1 1.4 9.0 0.2 5.7 3 2 4 7 7 7 3 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CEP17682.1 - 0.0013 19.3 0.8 15 6.2 0.0 4.5 3 2 2 5 5 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CEP17682.1 - 0.0086 16.2 1.8 2.9 8.1 0.0 3.7 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTTN_N PF14726.6 CEP17682.1 - 0.011 16.5 0.4 0.73 10.7 0.0 3.4 2 2 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning Atx10homo_assoc PF09759.9 CEP17682.1 - 0.058 13.4 6.3 0.8 9.8 0.2 4.4 3 2 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain YqfD PF06898.11 CEP17682.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD AcetDehyd-dimer PF09290.11 CEP17682.1 - 0.12 12.6 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation HEAT_PBS PF03130.16 CEP17682.1 - 0.17 12.6 13.0 1e+02 4.0 0.0 7.4 7 1 0 7 7 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 CEP17682.1 - 0.18 11.8 7.7 2.7 7.9 0.2 4.0 3 2 1 4 4 4 0 Myosin-binding striated muscle assembly central Sec62 PF03839.16 CEP17683.1 - 5.7e-49 166.6 0.2 7.2e-49 166.2 0.2 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 Tfb4 PF03850.14 CEP17684.1 - 7.4e-95 317.6 0.2 9.6e-95 317.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Phosducin PF02114.16 CEP17685.1 - 5.3e-21 74.7 0.5 6.4e-21 74.5 0.5 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CEP17685.1 - 8e-05 22.6 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin PI3_PI4_kinase PF00454.27 CEP17686.1 - 6.9e-53 180.0 0.0 1.5e-52 178.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 CEP17686.1 - 2.2e-35 122.2 0.2 2.2e-35 122.2 0.2 3.3 3 0 0 3 3 3 2 Serine/threonine-protein kinase smg-1 FATC PF02260.20 CEP17686.1 - 4.4e-13 48.8 0.5 1.6e-12 47.0 0.2 2.2 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 CEP17686.1 - 0.0039 17.3 0.2 0.75 10.2 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat FRB_dom PF08771.11 CEP17686.1 - 3.1 8.3 12.8 1.5 9.2 0.2 4.3 3 1 1 4 4 4 0 FKBP12-rapamycin binding domain CAP_GLY PF01302.25 CEP17691.1 - 1e-20 73.5 0.3 1.6e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CEP17691.1 - 1e-08 34.8 18.9 3e-05 23.8 6.1 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF3067 PF11267.8 CEP17691.1 - 0.067 13.8 1.8 0.19 12.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) Metallophos PF00149.28 CEP17692.1 - 1.4e-37 130.2 0.5 2.1e-37 129.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP17692.1 - 1.4e-14 54.3 0.1 3.6e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ATPgrasp_N PF18130.1 CEP17693.1 - 0.1 13.2 0.0 3.8 8.1 0.0 2.8 2 0 0 2 2 2 0 ATP-grasp N-terminal domain ATPase_2 PF01637.18 CEP17693.1 - 0.14 12.1 4.0 4.4 7.2 0.5 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_L18 PF17135.4 CEP17694.1 - 3e-88 294.1 5.3 3.4e-88 294.0 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CEP17694.1 - 0.00092 19.9 0.4 0.0024 18.5 0.4 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DDE_3 PF13358.6 CEP17695.1 - 0.00018 21.3 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_AsnC-type PF13404.6 CEP17695.1 - 0.0093 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Pox_A32 PF04665.12 CEP17696.1 - 0.033 13.6 0.6 0.09 12.2 0.3 1.7 1 1 1 2 2 2 0 Poxvirus A32 protein RhoGAP-FF1 PF16512.5 CEP17697.1 - 0.045 14.4 0.3 0.078 13.7 0.3 1.4 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain BioT2 PF15368.6 CEP17697.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 NDC10_II PF16787.5 CEP17701.1 - 2.5e-25 89.2 0.2 3e-19 69.2 0.1 2.1 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 NDC10_II PF16787.5 CEP17702.1 - 4e-37 127.9 3.2 1.4e-36 126.2 0.9 2.5 2 1 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP17702.1 - 4.1e-18 65.5 0.0 1.1e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HrcA PF01628.21 CEP17702.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF3391 PF11871.8 CEP17702.1 - 0.45 11.0 2.1 2.8 8.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DUF3446 PF11928.8 CEP17702.1 - 3.5 8.0 14.8 6.4 7.2 9.0 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain PIF1 PF05970.14 CEP17704.1 - 4.4e-13 49.1 0.2 5.4e-13 48.9 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase Retrotrans_gag PF03732.17 CEP17705.1 - 0.0048 17.1 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.26 CEP17706.1 - 1.3e-14 54.4 0.0 3.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP17706.1 - 1.8e-08 34.4 0.1 4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP17706.1 - 5.1e-06 26.6 0.3 1.1e-05 25.5 0.3 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 CEP17706.1 - 0.034 13.6 0.0 0.29 10.6 0.0 2.4 2 1 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CEP17707.1 - 3.8e-09 36.3 0.3 5.2e-09 35.9 0.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Med22 PF06179.12 CEP17711.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.9 2 1 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex GCR1_C PF12550.8 CEP17712.1 - 0.0025 18.1 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_32 PF13565.6 CEP17713.1 - 0.014 16.0 0.8 0.089 13.4 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain Asp_protease_2 PF13650.6 CEP17716.1 - 0.00021 21.9 0.0 0.00087 19.9 0.0 1.9 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP17716.1 - 0.0034 17.9 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP17716.1 - 0.018 14.8 0.4 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.10 CEP17716.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF2525 PF10733.9 CEP17719.1 - 0.025 14.8 0.9 43 4.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2525) FAM76 PF16046.5 CEP17719.1 - 0.85 8.9 4.8 1.2 8.4 4.8 1.2 1 0 0 1 1 1 0 FAM76 protein ANAPC4_WD40 PF12894.7 CEP17720.1 - 6.8e-13 48.7 0.1 9.3e-05 22.7 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP17720.1 - 4.3e-08 33.7 8.9 3.7e-05 24.4 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 CEP17720.1 - 2.7e-07 30.7 0.2 0.036 14.0 0.0 4.0 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A CC2-LZ PF16516.5 CEP17720.1 - 0.016 15.6 2.1 0.03 14.7 2.1 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF641 PF04859.12 CEP17720.1 - 0.053 13.8 0.4 0.13 12.6 0.4 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CEP17720.1 - 0.095 11.6 3.2 0.16 10.9 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 CEP17720.1 - 0.18 11.9 2.0 0.35 10.9 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3642 PF12182.8 CEP17720.1 - 0.21 11.9 1.7 0.5 10.7 0.0 2.4 4 0 0 4 4 4 0 Bacterial lipoprotein FAM76 PF16046.5 CEP17720.1 - 3.6 6.9 6.9 0.39 10.0 1.3 1.9 2 0 0 2 2 2 0 FAM76 protein RRM_1 PF00076.22 CEP17721.1 - 4.5e-56 186.6 0.4 9.7e-20 70.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP17721.1 - 1.1e-13 50.8 0.0 9.1e-06 25.3 0.1 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CEP17721.1 - 4.1e-10 39.4 0.0 0.0023 17.7 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CEP17721.1 - 1.3e-06 28.4 0.4 0.21 11.7 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 CEP17721.1 - 0.00048 20.3 2.5 0.26 11.5 0.0 3.0 2 1 1 3 3 3 2 RRM-like domain SET_assoc PF11767.8 CEP17721.1 - 0.0017 17.9 0.1 1.3 8.7 0.1 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 CEP17721.1 - 0.0051 16.8 0.5 7.5 6.6 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CEP17721.1 - 0.065 13.3 0.7 2.1 8.5 0.1 3.2 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 CEP17721.1 - 0.085 12.6 0.1 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 CEP17721.1 - 0.099 12.9 9.9 0.97 9.6 0.2 3.7 3 1 0 4 4 3 0 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 CEP17721.1 - 0.11 12.5 0.2 4.7 7.3 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain Ras PF00071.22 CEP17722.1 - 2.8e-54 183.1 0.0 3.1e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP17722.1 - 1.4e-23 83.3 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP17722.1 - 4.3e-10 39.3 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP17722.1 - 0.0006 19.2 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CEP17722.1 - 0.004 16.7 0.1 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP17722.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 CEP17722.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEP17722.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CEP17722.1 - 0.11 12.2 0.1 0.43 10.3 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Homoserine_dh PF00742.19 CEP17723.1 - 1e-50 172.0 0.0 1.6e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CEP17723.1 - 1.9e-21 76.9 0.0 4.2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CEP17723.1 - 0.0049 17.7 0.0 0.01 16.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 CEP17723.1 - 0.015 15.7 0.0 0.054 13.9 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CEP17723.1 - 0.017 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_9 PF13454.6 CEP17723.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding IGPS PF00218.21 CEP17723.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Sacchrp_dh_NADP PF03435.18 CEP17723.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 CEP17724.1 - 1.7e-26 93.2 0.0 3.1e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17724.1 - 4.9e-14 52.2 0.0 9.5e-14 51.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DDE_Tnp_1_6 PF13751.6 CEP17724.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF962 PF06127.11 CEP17725.1 - 2.7e-31 107.5 0.1 3.2e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Tecti-min-caps PF09300.10 CEP17725.1 - 0.027 14.5 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Tectiviridae, minor capsid UL42 PF17638.2 CEP17726.1 - 0.033 14.2 0.2 0.064 13.2 0.2 1.5 1 0 0 1 1 1 0 HCMV UL42 ThrE PF06738.12 CEP17727.1 - 1.4e-46 158.8 25.9 1.3e-44 152.4 4.7 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter PPI_Ypi1 PF07491.11 CEP17727.1 - 5.9e-23 80.5 8.2 1.5e-22 79.2 8.2 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor ThrE_2 PF12821.7 CEP17727.1 - 1.8e-10 41.0 33.5 1.6e-08 34.8 17.6 2.6 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE AF-4 PF05110.13 CEP17727.1 - 0.0048 15.1 4.4 0.006 14.7 4.4 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein CDC45 PF02724.14 CEP17727.1 - 0.019 13.3 1.2 0.027 12.8 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 CEP17727.1 - 0.05 13.2 6.6 0.086 12.4 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 CEP17727.1 - 0.56 9.9 3.8 0.94 9.1 3.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Trp_oprn_chp PF09534.10 CEP17727.1 - 1.1 9.1 7.0 0.1 12.4 1.4 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) IMUP PF15761.5 CEP17727.1 - 1.9 9.2 11.4 3.9 8.2 11.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DBP10CT PF08147.12 CEP17728.1 - 0.084 13.1 0.3 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Ints3 PF10189.9 CEP17729.1 - 2.6e-80 268.9 0.3 6.3e-80 267.7 0.3 1.7 1 0 0 1 1 1 1 Integrator complex subunit 3 RVT_1 PF00078.27 CEP17731.1 - 7.1e-41 140.1 0.0 1.5e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP17731.1 - 1.3e-07 31.4 0.1 3.8e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CEP17731.1 - 1.6e-07 31.9 0.3 5.3e-07 30.3 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.6 CEP17731.1 - 0.00033 20.5 0.1 0.00098 19.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase SNAPc19 PF15497.6 CEP17731.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 FliT PF05400.13 CEP17731.1 - 0.18 12.6 1.8 0.49 11.3 1.8 1.7 1 0 0 1 1 1 0 Flagellar protein FliT zf-CCHC_2 PF13696.6 CEP17732.1 - 1.6e-05 24.6 3.2 1.6e-05 24.6 3.2 3.3 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC PF00098.23 CEP17732.1 - 7.4e-05 22.6 1.6 7.4e-05 22.6 1.6 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 CEP17732.1 - 0.026 14.5 4.0 0.58 10.2 0.3 2.8 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 CEP17732.1 - 2 8.8 11.9 0.46 10.9 1.6 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G RhoGAP-FF1 PF16512.5 CEP17733.1 - 0.018 15.7 0.0 0.033 14.9 0.0 1.5 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain DUF1170 PF06663.13 CEP17733.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Integrase_H2C2 PF17921.1 CEP17736.1 - 6.7e-10 38.9 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP17736.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger Retrotrans_gag PF03732.17 CEP17737.1 - 4.5e-08 33.3 0.3 6.2e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CEP17737.1 - 1.9e-06 27.7 0.1 4.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CEP17737.1 - 0.032 14.3 2.2 0.057 13.5 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.22 CEP17737.1 - 2.9 7.0 5.4 4.3 6.5 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RT_RNaseH_2 PF17919.1 CEP17739.1 - 1.9e-25 88.8 0.0 2.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP17739.1 - 2.4e-15 56.7 0.0 3.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FYVE PF01363.21 CEP17740.1 - 3.4e-16 59.1 5.5 3.4e-16 59.1 5.5 3.2 3 1 0 3 3 3 1 FYVE zinc finger CSTF2_hinge PF14327.6 CEP17740.1 - 0.042 14.3 1.3 0.16 12.4 0.7 2.3 1 1 1 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 zf-AN1 PF01428.16 CEP17740.1 - 0.89 9.8 12.0 0.25 11.5 7.3 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger HEAT_EZ PF13513.6 CEP17741.1 - 6.8e-23 80.7 16.7 3.4e-11 43.4 0.0 9.7 9 2 1 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.6 CEP17741.1 - 1.8e-14 53.9 0.5 0.0028 18.0 0.0 6.7 5 2 3 8 8 8 5 HEAT repeats Vac14_Fab1_bd PF12755.7 CEP17741.1 - 2.9e-13 50.2 0.1 0.11 13.1 0.1 7.2 5 2 3 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CEP17741.1 - 8.4e-13 47.4 18.3 0.0041 17.3 0.1 8.9 10 0 0 10 10 10 5 HEAT repeat IBN_N PF03810.19 CEP17741.1 - 1.9e-11 43.7 0.0 7.4e-11 41.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 CEP17741.1 - 3.5e-08 33.7 0.1 0.056 13.5 0.1 4.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CEP17741.1 - 2.5e-05 23.6 2.9 0.025 13.7 0.0 4.0 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 CEP17741.1 - 0.0001 22.2 0.1 2.2 8.2 0.0 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3437) Tti2 PF10521.9 CEP17741.1 - 0.003 17.1 1.2 0.069 12.7 0.0 3.3 4 0 0 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 CEP17741.1 - 0.017 15.3 0.0 0.28 11.4 0.0 3.1 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 CEP17741.1 - 0.023 13.2 0.0 0.044 12.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 CEP17741.1 - 0.062 13.4 9.7 7.8 6.7 0.1 6.2 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 CEP17741.1 - 0.087 12.6 3.8 1.6 8.5 0.1 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis p450 PF00067.22 CEP17742.1 - 2.2e-61 208.0 0.1 2.5e-61 207.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 CEP17744.1 - 9.7e-139 463.3 11.1 1.2e-138 463.0 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEP17744.1 - 8.4e-65 217.7 6.5 1.2e-62 210.7 0.5 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP17744.1 - 1.8e-17 63.5 5.1 3.4e-07 30.6 0.2 5.1 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CEP17744.1 - 3.6e-11 42.3 2.5 0.007 16.5 0.0 6.1 7 0 0 7 7 6 2 HEAT repeat Arm PF00514.23 CEP17744.1 - 2e-08 34.0 0.6 0.017 15.2 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CEP17744.1 - 3.1e-05 24.4 0.6 0.99 10.0 0.0 5.2 5 1 1 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 CEP17744.1 - 0.0001 21.6 3.1 0.063 12.5 0.0 3.2 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CEP17744.1 - 0.00043 19.9 0.9 3.5 7.1 0.0 3.6 2 1 1 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 CEP17744.1 - 0.0029 17.8 5.2 8.8 6.5 0.4 4.3 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF4518 PF15008.6 CEP17744.1 - 0.019 14.1 3.7 0.04 13.1 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RasGEF_N_2 PF14663.6 CEP17744.1 - 0.031 14.7 3.6 0.58 10.6 0.0 4.1 3 3 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TFCD_C PF12612.8 CEP17744.1 - 0.039 13.8 0.6 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal ParcG PF10274.9 CEP17744.1 - 0.052 13.7 4.8 0.18 11.9 0.0 3.5 3 1 0 4 4 4 0 Parkin co-regulated protein HEAT_PBS PF03130.16 CEP17744.1 - 0.19 12.5 0.3 29 5.7 0.2 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat API5 PF05918.11 CEP17744.1 - 1.4 7.7 7.5 0.89 8.3 0.0 3.1 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Spt20 PF12090.8 CEP17744.1 - 6.4 6.3 18.4 13 5.4 18.4 1.4 1 0 0 1 1 1 0 Spt20 family TatD_DNase PF01026.21 CEP17745.1 - 2.3e-35 122.2 0.0 2.9e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RRM_1 PF00076.22 CEP17746.1 - 1.9e-17 62.8 0.0 2.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CEP17746.1 - 0.017 14.7 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 CEP17747.1 - 4.3e-18 65.0 0.1 1.7e-05 24.6 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein Prenylcys_lyase PF07156.14 CEP17748.1 - 2.5e-59 201.2 0.2 3.2e-59 200.9 0.2 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 CEP17748.1 - 2.6e-10 40.2 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CEP17748.1 - 2.8e-08 33.9 0.1 8.3e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CEP17748.1 - 4.7e-08 33.0 0.0 1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP17748.1 - 0.00028 20.9 0.9 0.6 10.1 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CEP17748.1 - 0.00068 18.9 0.1 0.019 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_2 PF02230.16 CEP17749.1 - 2.1e-20 73.4 0.0 2.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CEP17749.1 - 0.00076 19.2 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CEP17749.1 - 0.0084 16.7 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family C2 PF00168.30 CEP17750.1 - 4.7e-62 206.7 8.5 4.9e-16 58.9 0.0 6.3 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 CEP17750.1 - 7e-07 28.9 0.0 7.9e-06 25.5 0.0 2.3 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain SUZ PF12752.7 CEP17751.1 - 2e-05 25.2 1.0 4.5e-05 24.1 1.0 1.6 1 0 0 1 1 1 1 SUZ domain ABC_membrane_2 PF06472.15 CEP17752.1 - 6.8e-82 274.9 3.5 1.2e-81 274.1 3.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SCAMP PF04144.13 CEP17752.1 - 1.3e-42 146.1 15.4 2.9e-42 144.9 15.4 1.6 1 0 0 1 1 1 1 SCAMP family ABC_tran PF00005.27 CEP17752.1 - 2.6e-15 57.1 0.0 7.6e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CEP17752.1 - 0.00054 20.2 0.0 0.37 11.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP17752.1 - 0.00083 19.8 0.2 0.01 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CEP17752.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CEP17752.1 - 0.015 15.7 0.1 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CEP17752.1 - 0.044 13.2 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 CEP17752.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CEP17752.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CEP17752.1 - 0.14 12.7 0.0 0.79 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CEP17752.1 - 0.47 10.9 3.8 6.5 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain MBOAT PF03062.19 CEP17753.1 - 1.1e-40 140.1 18.2 1.5e-40 139.6 17.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DPM3 PF08285.11 CEP17754.1 - 3.5e-33 113.7 0.0 3.9e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4231 PF14015.6 CEP17754.1 - 0.0093 16.4 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF1624 PF07786.12 CEP17754.1 - 0.018 14.6 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Ribosomal_S17e PF00833.18 CEP17755.1 - 3.8e-63 210.9 0.3 5.2e-63 210.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal S17 CNH PF00780.22 CEP17756.1 - 3.5e-58 197.4 0.0 6.7e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP17756.1 - 4.7e-34 118.2 0.8 8.6e-34 117.4 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP17756.1 - 3.2e-22 79.1 0.0 8.9e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain LRR_4 PF12799.7 CEP17757.1 - 0.0076 16.6 15.5 0.95 10.0 0.1 6.4 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP17757.1 - 1.1 10.0 14.4 8.1 7.4 0.0 6.6 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 CEP17757.1 - 2.6 8.3 0.0 2.6 8.3 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat zf-C2H2_6 PF13912.6 CEP17759.1 - 0.00027 20.8 2.1 0.00082 19.3 2.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CEP17759.1 - 0.0063 17.2 13.7 0.007 17.1 3.1 4.0 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP17759.1 - 0.0064 16.8 1.5 0.039 14.2 0.9 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding GSH_synth_ATP PF03917.17 CEP17759.1 - 0.021 13.6 0.2 0.046 12.5 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic glutathione synthase, ATP binding domain TRAF6_Z2 PF18048.1 CEP17759.1 - 0.067 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 TFIID-18kDa PF02269.16 CEP17759.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf_ZIC PF18366.1 CEP17759.1 - 0.15 12.2 0.4 0.94 9.6 0.5 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 CEP17759.1 - 0.66 10.5 14.6 0.19 12.3 4.0 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type RVT_1 PF00078.27 CEP17760.1 - 5.2e-25 88.3 0.0 6.4e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AadA_C PF18280.1 CEP17761.1 - 0.13 12.4 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain WD40 PF00400.32 CEP17762.1 - 1.9e-09 38.0 9.0 0.00059 20.6 0.2 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat RRM_3 PF08777.11 CEP17763.1 - 0.0016 18.5 1.4 0.06 13.4 0.2 2.1 2 0 0 2 2 2 2 RNA binding motif Pribosyltran PF00156.27 CEP17764.1 - 1e-17 64.1 0.1 1.3e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEP17764.1 - 0.0046 16.4 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CEP17764.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Propeptide_C1 PF08127.13 CEP17764.1 - 0.056 13.3 0.4 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C1 propeptide TAP42 PF04177.12 CEP17765.1 - 1.8e-92 309.9 10.2 2e-92 309.7 10.2 1.0 1 0 0 1 1 1 1 TAP42-like family Spectrin_like PF18373.1 CEP17765.1 - 0.05 13.7 0.8 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Spectrin like domain Trans_reg_C PF00486.28 CEP17765.1 - 0.097 12.8 0.2 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Matrilin_ccoil PF10393.9 CEP17765.1 - 0.84 9.5 3.4 17 5.4 0.0 2.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin E1_dh PF00676.20 CEP17766.1 - 1.2e-63 214.9 0.0 1.6e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CEP17766.1 - 5.7e-62 208.5 0.0 8.5e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CEP17766.1 - 7e-56 188.1 0.1 1.1e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CEP17766.1 - 6.1e-19 67.3 0.5 6.1e-19 67.3 0.5 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus EF-hand_7 PF13499.6 CEP17767.1 - 9e-21 74.1 0.5 2.9e-14 53.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CEP17767.1 - 8.9e-20 68.7 6.9 2.9e-07 29.6 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CEP17767.1 - 6.2e-19 67.6 6.9 6.1e-08 32.4 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CEP17767.1 - 3e-15 54.8 2.3 0.0002 21.0 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CEP17767.1 - 1.1e-11 43.6 8.7 0.00019 20.8 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CEP17767.1 - 4.4e-08 33.0 1.9 0.049 13.6 0.1 3.0 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEP17767.1 - 9.2e-07 29.1 0.0 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain p25-alpha PF05517.12 CEP17767.1 - 1.7e-05 25.0 0.5 0.00064 19.9 0.8 2.1 1 1 1 2 2 2 1 p25-alpha SPARC_Ca_bdg PF10591.9 CEP17767.1 - 0.00034 20.9 0.2 0.066 13.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CEP17767.1 - 0.00053 20.1 1.0 0.01 16.0 1.0 2.5 1 1 1 2 2 2 2 Dockerin type I domain Ribosomal_60s PF00428.19 CEP17767.1 - 0.0056 17.2 0.4 0.11 13.1 0.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1456 PF07308.13 CEP17767.1 - 0.014 15.7 0.3 0.57 10.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Ribosomal_L18_c PF14204.6 CEP17767.1 - 0.099 13.6 0.2 0.27 12.2 0.1 1.7 1 1 0 2 2 2 0 Ribosomal L18 C-terminal region PIF1 PF05970.14 CEP17768.1 - 2.7e-09 36.7 0.1 3.1e-09 36.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PEPCK_ATP PF01293.20 CEP17769.1 - 5.5e-216 717.7 0.0 6.7e-216 717.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 CEP17769.1 - 0.088 13.2 0.0 0.2 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain KilA-N PF04383.13 CEP17770.1 - 0.00053 19.8 0.0 0.0022 17.8 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain SUIM_assoc PF16619.5 CEP17770.1 - 0.071 13.2 9.8 0.12 12.4 3.6 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 CEP17770.1 - 0.71 10.5 9.4 2.4 8.8 5.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Arrestin_C PF02752.22 CEP17771.1 - 1.5e-13 51.4 6.8 5.5e-12 46.3 2.8 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP17771.1 - 9.4e-12 45.2 1.1 3.3e-06 27.2 0.1 3.9 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CEP17771.1 - 0.00028 20.2 1.9 0.06 12.5 0.2 2.4 2 1 0 2 2 2 2 Rgp1 Alpha_adaptinC2 PF02883.20 CEP17771.1 - 0.028 14.7 0.4 0.092 13.1 0.3 2.0 2 0 0 2 2 2 0 Adaptin C-terminal domain Ribosomal_L17 PF01196.19 CEP17772.1 - 8.3e-37 126.0 1.0 1.9e-36 124.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 GCV_T PF01571.21 CEP17773.1 - 1.5e-10 40.9 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Ribo_biogen_C PF04034.13 CEP17774.1 - 8.8e-51 170.9 0.0 1.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CEP17774.1 - 2.7e-10 39.9 1.0 4.6e-10 39.2 1.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI TFIIA PF03153.13 CEP17774.1 - 2 8.3 12.1 3.2 7.7 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SCP2 PF02036.17 CEP17775.1 - 6e-24 84.5 1.5 7.5e-24 84.1 1.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CEP17775.1 - 0.00033 20.9 0.3 0.00043 20.5 0.3 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal COQ7 PF03232.13 CEP17776.1 - 6e-76 254.0 0.3 7.2e-76 253.8 0.3 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PNK3P PF08645.11 CEP17777.1 - 1.7e-58 196.9 0.6 2.9e-58 196.1 0.6 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CEP17777.1 - 7.8e-18 65.0 0.0 3.6e-09 36.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain HAD_2 PF13419.6 CEP17777.1 - 0.00076 19.6 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 CEP17777.1 - 0.0027 17.0 0.1 1.3 8.3 0.0 2.6 2 1 1 3 3 3 2 Zeta toxin KTI12 PF08433.10 CEP17777.1 - 0.0029 17.1 2.2 0.37 10.2 2.2 2.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 CEP17777.1 - 0.0081 16.2 0.0 0.039 14.1 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.18 CEP17777.1 - 0.063 12.6 0.3 0.87 8.8 0.0 2.5 2 1 1 3 3 3 0 6-phosphofructo-2-kinase HAD PF12710.7 CEP17777.1 - 0.082 13.3 0.0 2.6 8.4 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CEP17777.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase MOZART1 PF12554.8 CEP17778.1 - 1.6e-24 85.4 0.7 2.9e-24 84.6 0.7 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SNAPc_SNAP43 PF09808.9 CEP17778.1 - 0.005 16.8 7.3 0.012 15.6 6.3 2.2 1 1 1 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Xan_ur_permease PF00860.20 CEP17779.1 - 2.6e-33 115.3 24.5 1.3e-31 109.7 24.5 2.7 1 1 0 1 1 1 1 Permease family WD40 PF00400.32 CEP17781.1 - 1.3e-45 152.5 16.6 5.6e-09 36.5 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17781.1 - 2.2e-10 40.7 0.3 0.00052 20.2 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP17781.1 - 4.1e-06 25.7 7.4 0.099 11.3 0.1 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 CEP17781.1 - 0.0041 16.2 0.1 0.039 13.0 0.0 2.4 3 0 0 3 3 3 1 Coatomer WD associated region COPI_C PF06957.11 CEP17782.1 - 4.7e-147 490.0 0.8 6e-147 489.6 0.8 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CEP17782.1 - 1.4e-119 400.1 0.7 2e-119 399.6 0.7 1.2 1 0 0 1 1 1 1 Coatomer WD associated region His_Me_b4a2 PF18275.1 CEP17782.1 - 0.081 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Baculo_IE-1 PF05290.11 CEP17782.1 - 0.1 12.6 2.5 0.32 10.9 2.5 1.9 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TPR_2 PF07719.17 CEP17782.1 - 0.13 12.5 0.8 3.1 8.1 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 CEP17783.1 - 2.6e-06 27.7 6.3 2.6e-06 27.7 6.3 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 CEP17783.1 - 2.5e-05 23.9 1.0 4.4e-05 23.0 1.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger RINGv PF12906.7 CEP17783.1 - 0.00069 19.7 6.3 0.00069 19.7 6.3 1.8 2 0 0 2 2 1 1 RING-variant domain zf-RING_UBOX PF13445.6 CEP17783.1 - 0.0016 18.4 3.5 0.0016 18.4 3.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger C1_1 PF00130.22 CEP17783.1 - 0.011 15.6 2.2 0.011 15.6 2.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CEP17783.1 - 0.02 14.8 2.7 0.02 14.8 2.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CEP17783.1 - 0.024 14.2 4.6 0.045 13.3 4.6 1.5 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.19 CEP17783.1 - 0.063 13.2 6.4 0.34 10.9 6.4 2.4 1 0 0 1 1 1 0 AT hook motif PHD PF00628.29 CEP17783.1 - 0.11 12.4 7.7 0.25 11.2 7.7 1.7 1 0 0 1 1 1 0 PHD-finger FYVE PF01363.21 CEP17783.1 - 0.14 12.3 5.8 0.55 10.4 5.8 1.9 1 1 0 1 1 1 0 FYVE zinc finger Zf_RING PF16744.5 CEP17783.1 - 0.2 11.8 3.4 0.53 10.4 3.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 CEP17783.1 - 0.72 10.1 6.9 2.1 8.6 6.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 CEP17783.1 - 1.4 9.0 4.8 3.3 7.8 4.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 CEP17783.1 - 2.2 8.4 8.6 0.082 13.0 2.3 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CEP17783.1 - 6.5 6.6 14.8 0.15 11.9 7.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain p450 PF00067.22 CEP17784.1 - 3.5e-97 326.1 0.1 5.3e-97 325.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 CEP17784.1 - 2.1e-31 109.2 0.0 1.5e-30 106.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP17784.1 - 1e-24 87.3 0.2 2.1e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CEP17784.1 - 6.6e-16 58.9 0.0 1.6e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SBP_bac_5 PF00496.22 CEP17784.1 - 0.036 13.0 0.1 0.073 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle NAAA-beta PF15508.6 CEP17784.1 - 0.12 12.7 0.1 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HSF_DNA-bind PF00447.17 CEP17785.1 - 2.1e-31 108.4 0.7 2.1e-31 108.4 0.7 2.7 2 0 0 2 2 2 1 HSF-type DNA-binding Macoilin PF09726.9 CEP17785.1 - 0.00024 19.9 20.7 0.00024 19.9 20.7 2.9 3 0 0 3 3 3 1 Macoilin family FlaC_arch PF05377.11 CEP17785.1 - 0.045 14.1 2.7 3.6 8.0 0.1 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GATase_2 PF00310.21 CEP17786.1 - 2.2e-177 590.0 0.0 2.9e-177 589.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CEP17786.1 - 5.3e-155 516.1 0.3 1.1e-153 511.7 0.1 2.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CEP17786.1 - 2.2e-116 388.3 0.0 1.6e-115 385.4 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CEP17786.1 - 3.3e-84 281.2 2.5 5.4e-84 280.5 2.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CEP17786.1 - 1.5e-26 93.4 0.0 5.9e-26 91.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CEP17786.1 - 9.7e-24 83.3 0.1 2e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CEP17786.1 - 5.7e-09 36.1 0.0 1.8e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CEP17786.1 - 2.1e-07 30.5 0.4 0.066 12.5 0.0 3.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP17786.1 - 4.3e-07 30.4 0.3 0.00031 21.3 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CEP17786.1 - 2.4e-06 27.4 0.2 0.015 14.9 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CEP17786.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CEP17786.1 - 3.9e-05 22.5 1.3 5.4e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CEP17786.1 - 9.1e-05 22.0 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CEP17786.1 - 0.00052 20.4 0.0 0.72 10.3 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CEP17786.1 - 0.00062 19.0 0.2 0.0033 16.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 CEP17786.1 - 0.0014 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 CEP17786.1 - 0.004 16.5 0.1 0.067 12.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CEP17786.1 - 0.0057 15.9 0.4 0.096 11.9 0.1 2.8 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 CEP17786.1 - 0.011 14.8 0.1 0.075 12.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 CEP17786.1 - 0.047 13.0 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.18 CEP17786.1 - 0.085 11.9 0.5 0.19 10.7 0.5 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 CEP17786.1 - 0.086 12.8 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.6 CEP17786.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Shikimate_DH PF01488.20 CEP17786.1 - 0.12 12.4 0.1 37 4.4 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase LSM14 PF12701.7 CEP17787.1 - 8.5e-31 105.9 0.1 2e-30 104.7 0.1 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CEP17787.1 - 4.8e-07 30.6 10.4 1.5e-05 25.8 0.5 4.3 4 2 1 5 5 5 2 FDF domain SM-ATX PF14438.6 CEP17787.1 - 1.5e-06 28.3 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain AAA_12 PF13087.6 CEP17788.1 - 6e-13 48.9 0.1 1.4e-12 47.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP17788.1 - 2.6e-11 43.8 1.0 2.5e-09 37.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CEP17788.1 - 1.7e-06 27.9 0.1 1e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CEP17788.1 - 5.6e-06 26.7 0.0 5e-05 23.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP17788.1 - 0.00071 20.0 0.5 0.0021 18.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP17788.1 - 0.00079 19.7 0.0 0.0034 17.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CEP17788.1 - 0.0027 17.2 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 CEP17788.1 - 0.0028 17.6 0.0 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CEP17788.1 - 0.0032 17.8 0.0 0.035 14.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA PF00004.29 CEP17788.1 - 0.0035 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CEP17788.1 - 0.013 15.3 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CEP17788.1 - 0.015 14.7 0.1 0.036 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CEP17788.1 - 0.053 13.1 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP17788.1 - 0.06 13.6 0.6 0.23 11.7 0.0 2.3 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 CEP17788.1 - 0.061 13.2 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.6 CEP17788.1 - 0.17 12.4 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CEP17788.1 - 1.1 8.5 4.6 0.42 9.8 0.0 2.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) LRR_8 PF13855.6 CEP17789.1 - 1.9e-18 66.0 24.7 1.9e-11 43.5 4.1 3.1 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CEP17789.1 - 5.9e-14 52.0 16.8 1.4e-08 34.9 2.1 3.7 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP17789.1 - 1.1e-05 25.2 9.8 2.1 9.2 0.0 6.0 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 CEP17789.1 - 0.00032 20.2 6.7 0.0032 17.0 4.7 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CEP17789.1 - 0.079 13.1 12.0 20 5.6 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat MBR1 PF17058.5 CEP17789.1 - 3.6 7.9 16.1 0.44 10.8 11.2 1.9 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Ank_4 PF13637.6 CEP17790.1 - 5.7e-14 52.3 2.3 1.7e-07 31.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP17790.1 - 5.6e-11 42.4 3.5 2.2e-09 37.3 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CEP17790.1 - 1.5e-10 41.5 1.0 2.7e-10 40.7 0.6 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP17790.1 - 5.4e-09 35.6 0.4 1.9e-06 27.8 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CEP17790.1 - 9.2e-09 35.4 0.2 2e-08 34.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4791 PF16039.5 CEP17790.1 - 0.0031 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4791) RGS PF00615.19 CEP17791.1 - 1.8e-22 79.8 0.6 1.9e-21 76.5 0.6 2.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 CEP17791.1 - 5.8e-10 39.1 0.1 1e-07 31.9 0.0 3.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YL1 PF05764.13 CEP17791.1 - 0.4 10.8 8.3 0.74 9.9 8.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PrmA PF06325.13 CEP17794.1 - 7.4e-13 48.5 0.3 7.4e-13 48.5 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CEP17794.1 - 1.1e-11 44.6 0.1 2e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 CEP17794.1 - 8.7e-07 28.8 0.0 1.9e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 CEP17794.1 - 3.4e-06 27.7 0.0 8.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP17794.1 - 1.9e-05 24.5 0.2 2.7e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEP17794.1 - 2.7e-05 23.9 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DUF43 PF01861.16 CEP17794.1 - 0.0024 17.1 0.7 0.0057 15.9 0.2 1.5 1 1 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_11 PF08241.12 CEP17794.1 - 0.0025 18.4 0.0 0.038 14.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP17794.1 - 0.012 16.4 1.2 0.022 15.5 0.1 2.1 2 2 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 CEP17794.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 CEP17794.1 - 0.031 14.1 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CEP17794.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 CEP17794.1 - 0.087 12.8 0.4 0.36 10.8 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain HSP70 PF00012.20 CEP17795.1 - 5.2e-261 867.1 9.5 5.9e-261 866.9 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP17795.1 - 1.7e-16 60.0 0.1 4.9e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CEP17795.1 - 0.0049 16.6 0.0 0.0097 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CEP17795.1 - 0.037 13.3 0.3 0.098 11.9 0.2 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF3849 PF12960.7 CEP17795.1 - 0.085 12.9 1.0 0.21 11.6 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) SAPIS-gp6 PF16722.5 CEP17795.1 - 0.42 11.1 5.3 0.21 12.0 2.2 2.1 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus ISG65-75 PF11727.8 CEP17795.1 - 1.2 8.3 11.3 0.78 8.9 7.3 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein SSPI PF14098.6 CEP17795.1 - 1.9 8.7 4.6 7.7 6.8 0.2 3.2 3 0 0 3 3 3 0 Small, acid-soluble spore protein I CK_II_beta PF01214.18 CEP17796.1 - 1.6e-72 243.2 0.0 6.1e-72 241.3 0.0 1.8 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Vpu PF00558.19 CEP17797.1 - 0.7 9.7 4.7 12 5.8 0.7 2.5 2 0 0 2 2 2 0 Vpu protein Not1 PF04054.15 CEP17798.1 - 1.9e-145 484.5 2.6 1.9e-145 484.5 2.6 2.5 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CEP17798.1 - 2.1e-93 311.8 5.0 4.6e-93 310.7 5.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CEP17798.1 - 2.4e-67 225.8 0.1 2.4e-67 225.8 0.1 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CEP17798.1 - 2.7e-54 183.1 6.1 2.7e-54 183.1 6.1 2.9 3 0 0 3 3 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CEP17798.1 - 3e-37 128.0 0.4 3e-37 128.0 0.4 3.3 3 1 0 3 3 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Suf PF05843.14 CEP17798.1 - 0.0027 17.7 9.5 0.007 16.4 9.5 1.7 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) ORC_WH_C PF18137.1 CEP17798.1 - 0.01 15.9 2.3 0.025 14.6 2.3 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal TBCC_N PF16752.5 CEP17798.1 - 0.019 15.4 7.5 0.1 13.1 7.5 2.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain DUF4407 PF14362.6 CEP17798.1 - 0.029 13.7 2.1 0.054 12.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpb4 PF03874.16 CEP17798.1 - 0.049 14.0 0.8 0.77 10.1 0.5 3.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 TFIIA PF03153.13 CEP17798.1 - 0.23 11.4 28.0 0.0076 16.3 20.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RGS PF00615.19 CEP17799.1 - 5.7e-06 26.6 0.4 3.5e-05 24.0 0.4 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain Chromo PF00385.24 CEP17801.1 - 1.5e-10 40.8 0.4 3.5e-10 39.6 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CEP17801.1 - 3.1e-05 24.0 0.8 0.0034 17.4 0.1 2.6 2 0 0 2 2 2 1 Chromo shadow domain SR-25 PF10500.9 CEP17801.1 - 0.21 11.2 21.0 1 8.9 4.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3807 PF12720.7 CEP17801.1 - 2 8.7 16.1 4.2 7.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Pex14_N PF04695.13 CEP17801.1 - 2.1 9.0 14.6 1.6 9.3 5.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SKA1 PF07160.12 CEP17801.1 - 6.7 6.5 13.5 2.9 7.7 3.3 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF92 PF01940.16 CEP17802.1 - 1e-74 250.9 4.0 1.2e-74 250.7 4.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF1430 PF07242.11 CEP17802.1 - 0.039 14.2 0.8 6.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Proteasome PF00227.26 CEP17803.1 - 8.6e-62 208.0 0.1 1.1e-61 207.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP17803.1 - 6.3e-14 51.3 0.1 1.3e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 CEP17806.1 - 4.6e-13 49.4 11.7 0.0014 19.4 0.5 8.1 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17806.1 - 1.7e-08 34.6 5.1 0.22 11.8 0.0 6.2 5 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain KH_6 PF15985.5 CEP17807.1 - 9.9e-19 67.4 0.1 1.9e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CEP17807.1 - 4.6e-11 42.5 0.0 9.7e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain ECR1_N PF14382.6 CEP17807.1 - 0.015 15.0 0.8 0.027 14.3 0.0 1.8 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Cys_Met_Meta_PP PF01053.20 CEP17808.1 - 1.5e-35 122.4 0.0 2.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEP17808.1 - 0.0049 16.1 0.0 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Sugar_tr PF00083.24 CEP17809.1 - 4.2e-96 322.6 26.1 1.1e-93 314.6 26.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP17809.1 - 6.5e-33 114.1 28.8 9.8e-32 110.2 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_I_TF PF04090.12 CEP17810.1 - 0.0015 18.1 0.9 0.0085 15.6 0.0 2.5 3 1 0 3 3 3 1 RNA polymerase I specific initiation factor RNA_pol_Rpb1_3 PF04983.18 CEP17810.1 - 0.029 14.3 2.0 0.071 13.1 2.0 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Par3_HAL_N_term PF12053.8 CEP17810.1 - 0.044 14.0 0.3 0.044 14.0 0.3 2.0 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins PPR_2 PF13041.6 CEP17810.1 - 0.12 12.6 0.0 5.9 7.2 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family ADK PF00406.22 CEP17811.1 - 6.1e-60 201.7 0.0 8.2e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEP17811.1 - 1.1e-20 74.4 0.1 2.3e-20 73.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CEP17811.1 - 3.1e-18 65.4 0.0 6.1e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CEP17811.1 - 0.00019 22.0 0.0 0.00045 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP17811.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CEP17811.1 - 0.086 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Hydin_ADK PF17213.3 CEP17811.1 - 0.11 12.7 0.5 1 9.6 0.1 2.2 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain KxDL PF10241.9 CEP17811.1 - 0.2 12.0 0.6 0.46 10.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein SNF2_N PF00176.23 CEP17812.1 - 5.1e-66 222.8 0.0 1.1e-65 221.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP17812.1 - 2e-20 73.2 0.0 1.5e-19 70.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CEP17812.1 - 4.8e-06 26.0 0.7 9e-05 21.8 0.0 3.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.6 CEP17812.1 - 0.56 9.9 0.0 0.56 9.9 0.0 4.1 3 1 0 3 3 3 0 AAA domain Arm PF00514.23 CEP17813.1 - 1.1e-15 57.1 4.7 6.6e-08 32.3 0.1 7.3 6 1 1 7 7 7 4 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 CEP17813.1 - 0.0023 18.1 0.2 0.45 10.8 0.0 4.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 CEP17813.1 - 0.049 14.2 0.5 1.3 9.6 0.1 3.1 3 1 1 4 4 4 0 HEAT-like repeat PMT_4TMC PF16192.5 CEP17813.1 - 1 8.9 5.3 0.11 12.1 0.9 1.6 2 0 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Phage_int_SAM_1 PF02899.17 CEP17814.1 - 2.1e-05 24.7 0.2 6.3e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP17814.1 - 0.00065 20.1 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF4170 PF13773.6 CEP17814.1 - 0.18 12.0 0.3 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4170) DUF1604 PF07713.13 CEP17815.1 - 0.5 10.2 3.7 0.5 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) MRPL52 PF18699.1 CEP17816.1 - 1.5 9.1 8.5 1.4 9.1 2.1 2.8 2 1 0 2 2 2 0 Mitoribosomal protein mL52 IF-2B PF01008.17 CEP17817.1 - 2.8e-63 213.8 1.6 7.2e-63 212.4 1.6 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family TPP_enzyme_N PF02776.18 CEP17818.1 - 2.4e-30 105.4 0.0 4.2e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CEP17818.1 - 3.7e-17 62.5 0.1 2.3e-15 56.7 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEP17818.1 - 7.3e-17 61.4 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF362 PF04015.12 CEP17818.1 - 0.00041 20.7 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF362) PseudoU_synth_2 PF00849.22 CEP17819.1 - 3e-28 98.9 0.0 4.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CEP17819.1 - 0.0024 17.5 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain RRM_1 PF00076.22 CEP17820.1 - 3.1e-22 78.2 0.0 9.7e-11 41.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_5 PF13857.6 CEP17821.1 - 3.5e-11 43.1 0.2 1.2e-07 31.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP17821.1 - 9.6e-11 41.6 0.0 5.6e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CEP17821.1 - 1.1e-10 42.0 0.0 2.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 CEP17821.1 - 1.4e-09 37.9 1.5 2.1e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 CEP17821.1 - 8.6e-07 29.4 0.1 3.5e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP17821.1 - 1.5e-06 28.1 0.0 0.088 13.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DUF2722 PF10846.8 CEP17821.1 - 0.0053 15.8 21.4 0.0053 15.8 21.4 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF2722) AAA_23 PF13476.6 CEP17821.1 - 0.22 12.0 19.5 0.1 13.1 5.5 2.8 2 0 0 2 2 2 0 AAA domain eIF-3_zeta PF05091.12 CEP17821.1 - 5.5 5.8 37.1 0.18 10.7 13.6 3.4 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SRP40_C PF05022.12 CEP17822.1 - 9.3e-28 96.9 2.9 9.3e-28 96.9 2.9 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.11 CEP17822.1 - 0.034 14.1 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 LisH zf-CCCH_4 PF18044.1 CEP17823.1 - 1.7e-14 53.2 7.8 6.1e-07 29.1 1.0 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CEP17823.1 - 7.3e-11 41.8 18.5 2.1e-06 27.6 4.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CEP17823.1 - 1.3e-10 40.9 7.9 8.3e-06 25.6 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CEP17823.1 - 3.7e-06 27.6 18.4 0.0013 19.4 1.1 3.4 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 CEP17823.1 - 9.4e-05 22.6 2.7 9.4e-05 22.6 2.7 2.2 2 0 0 2 2 2 1 Zinc-finger containing family BSP_II PF05432.11 CEP17823.1 - 0.0048 16.6 3.2 0.0048 16.6 3.2 1.6 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) zf-CCCH_2 PF14608.6 CEP17823.1 - 0.029 14.8 15.1 0.035 14.6 2.7 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF3488 PF11992.8 CEP17823.1 - 0.18 10.7 2.0 0.31 9.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Disintegrin PF00200.23 CEP17823.1 - 0.51 11.2 4.8 1 10.2 4.8 1.5 1 0 0 1 1 1 0 Disintegrin BTB_2 PF02214.22 CEP17824.1 - 3.2e-12 46.6 0.2 4.9e-06 26.8 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 CEP17824.1 - 0.0037 17.5 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain fn3_2 PF16893.5 CEP17826.1 - 9.4e-34 115.4 0.1 1.6e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CEP17826.1 - 2.5e-28 97.8 0.2 4.9e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 CEP17826.1 - 2.3e-10 40.3 0.0 5.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CEP17826.1 - 3e-10 40.4 0.0 1.1e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 CEP17826.1 - 0.0011 19.3 0.0 0.0051 17.1 0.0 2.1 2 1 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.8 CEP17826.1 - 0.0022 18.2 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 CEP17826.1 - 0.0026 18.1 0.0 0.007 16.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain N_BRCA1_IG PF16158.5 CEP17826.1 - 0.059 14.1 0.0 0.46 11.3 0.0 2.2 2 0 0 2 2 2 0 Ig-like domain from next to BRCA1 gene BRCT_3 PF18428.1 CEP17826.1 - 0.066 13.3 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ANAPC4_WD40 PF12894.7 CEP17827.1 - 1.9e-14 53.7 0.1 2.2e-07 31.1 0.2 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP17827.1 - 2.8e-08 34.3 3.7 0.59 11.1 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Alginate_lyase PF05426.12 CEP17828.1 - 2e-16 60.4 0.1 2.6e-15 56.7 0.1 2.3 1 1 0 1 1 1 1 Alginate lyase Suppressor_APC PF11414.8 CEP17828.1 - 0.44 10.6 12.5 0.1 12.7 8.2 2.0 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Creatinase_N_2 PF16189.5 CEP17829.1 - 1.5e-47 161.7 0.0 3.7e-46 157.2 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CEP17829.1 - 7.1e-46 156.5 0.0 1.2e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CEP17829.1 - 2e-16 60.8 0.0 5.1e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DUF4162 PF13732.6 CEP17829.1 - 0.011 16.5 0.0 0.082 13.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) PP-binding PF00550.25 CEP17830.1 - 4.4e-14 52.6 0.2 5.7e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CEP17830.1 - 1.6e-06 28.2 1.3 2.7e-06 27.5 1.3 1.4 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 CEP17830.1 - 0.092 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Peptidase_C54 PF03416.19 CEP17831.1 - 6.1e-83 278.4 0.0 1.3e-58 198.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase family C54 tRNA_U5-meth_tr PF05958.11 CEP17832.1 - 7e-13 48.3 3.7 2.5e-12 46.5 0.3 3.2 2 2 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CEP17832.1 - 2.1e-09 37.4 0.0 6.5e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEP17832.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CEP17832.1 - 1.4e-07 31.2 0.1 4.2e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEP17832.1 - 2.5e-07 31.3 0.2 1.7e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 CEP17832.1 - 2.1e-06 27.4 0.9 5.1e-06 26.1 0.1 2.0 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 CEP17832.1 - 0.0018 18.0 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CEP17832.1 - 0.0091 16.0 3.9 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP17832.1 - 0.019 14.3 0.1 0.056 12.8 0.1 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 CEP17832.1 - 0.029 14.0 0.2 0.071 12.7 0.2 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 CEP17832.1 - 0.039 14.6 0.1 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TPMT PF05724.11 CEP17832.1 - 0.039 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 CEP17832.1 - 0.044 13.2 0.3 0.044 13.2 0.3 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_23 PF13489.6 CEP17832.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CEP17832.1 - 0.1 11.6 0.2 0.71 8.9 0.0 2.3 2 1 1 3 3 3 0 DREV methyltransferase AviRa PF11599.8 CEP17832.1 - 0.89 9.0 4.8 0.34 10.3 0.1 2.5 3 1 0 3 3 3 0 RRNA methyltransferase AviRa Herpes_US9 PF06072.11 CEP17833.1 - 0.28 11.1 1.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MafB19-deam PF14437.6 CEP17834.1 - 1.5e-10 40.9 0.0 1.8e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 CEP17834.1 - 6.9e-10 38.7 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.6 CEP17834.1 - 0.0024 18.0 0.1 0.0051 16.9 0.1 1.6 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 CEP17834.1 - 0.0081 16.3 1.2 0.013 15.6 1.2 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CEP17834.1 - 0.012 15.7 1.1 0.018 15.2 1.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 CEP17834.1 - 0.037 14.1 0.4 0.054 13.6 0.4 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 CEP17834.1 - 0.042 13.8 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain G-alpha PF00503.20 CEP17835.1 - 1.8e-117 392.5 5.8 2.2e-117 392.2 5.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP17835.1 - 8.8e-14 51.3 2.0 8.6e-10 38.3 0.1 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP17835.1 - 0.00046 19.6 4.2 0.0077 15.6 0.2 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP17835.1 - 0.0029 17.7 0.3 0.55 10.3 0.3 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CEP17835.1 - 0.0065 16.7 0.3 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEP17835.1 - 0.013 15.0 0.7 0.1 12.1 0.2 2.5 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CEP17835.1 - 0.065 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CEP17835.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CEP17835.1 - 0.066 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_pol_Rpb2_6 PF00562.28 CEP17836.1 - 9.7e-123 410.1 0.9 1.2e-122 409.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CEP17836.1 - 1.9e-59 200.6 0.4 2.9e-59 200.0 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CEP17836.1 - 4.4e-35 120.0 0.6 2.1e-34 117.8 0.6 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CEP17836.1 - 1.2e-33 116.4 3.2 3.2e-33 115.0 2.9 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CEP17836.1 - 5.2e-23 81.1 3.1 1.2e-22 79.9 2.5 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CEP17836.1 - 8.7e-22 77.1 0.1 9.6e-21 73.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CEP17836.1 - 6.3e-10 39.5 1.5 2.1e-09 37.8 1.5 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 XisI PF08869.11 CEP17836.1 - 0.074 13.4 0.3 0.22 11.9 0.3 1.8 1 0 0 1 1 1 0 XisI protein D5_N PF08706.11 CEP17837.1 - 0.092 13.0 1.2 0.16 12.3 1.2 1.3 1 0 0 1 1 1 0 D5 N terminal like Inhibitor_I9 PF05922.16 CEP17840.1 - 4.5e-06 27.2 0.1 5.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cob_adeno_trans PF01923.18 CEP17841.1 - 6.1e-38 130.5 0.0 2.7e-37 128.4 0.0 2.1 2 0 0 2 2 2 1 Cobalamin adenosyltransferase Na_sulph_symp PF00939.19 CEP17841.1 - 5.4e-30 104.8 36.3 7.7e-30 104.3 36.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CEP17841.1 - 8.3e-29 100.7 43.1 6.8e-19 68.2 17.3 2.1 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 CEP17841.1 - 1.8e-17 64.4 14.1 3.6e-14 53.5 0.1 3.6 3 1 1 4 4 4 3 SPX domain PHM7_ext PF12621.8 CEP17841.1 - 0.2 11.8 0.1 0.48 10.6 0.1 1.6 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Saf_2TM PF18303.1 CEP17841.1 - 7.5 6.1 11.9 0.65 9.6 0.2 3.4 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain 60KD_IMP PF02096.20 CEP17842.1 - 5.2e-15 55.7 4.5 3.6e-14 53.0 4.5 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Mac PF12464.8 CEP17842.1 - 9.8e-11 41.7 0.1 3.1e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep PF00132.24 CEP17842.1 - 1.7e-10 40.2 14.6 5.9e-09 35.3 7.5 3.5 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CEP17842.1 - 0.00037 20.2 15.9 0.0011 18.6 10.0 2.9 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase FtsX PF02687.21 CEP17842.1 - 1.7 9.2 5.7 0.69 10.4 0.7 2.4 2 0 0 2 2 2 0 FtsX-like permease family FMO-like PF00743.19 CEP17843.1 - 1.1e-15 57.0 0.3 3.4e-15 55.5 0.2 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CEP17843.1 - 1.1e-10 41.6 0.1 3.7e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEP17843.1 - 1.4e-10 40.8 0.4 2.5e-09 36.7 0.1 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CEP17843.1 - 0.00012 21.4 0.0 0.00095 18.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CEP17843.1 - 0.00022 21.2 0.3 0.0059 16.6 0.0 2.6 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 CEP17843.1 - 0.00083 19.0 0.0 0.0016 18.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase EABR PF12180.8 CEP17843.1 - 0.073 12.7 1.0 1.3 8.7 0.3 2.3 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 EF-hand_1 PF00036.32 CEP17844.1 - 2.8e-28 95.3 9.2 1.7e-09 36.6 1.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CEP17844.1 - 1.2e-23 81.4 8.2 5.4e-08 32.0 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CEP17844.1 - 9.9e-21 71.9 7.0 9.4e-06 25.2 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CEP17844.1 - 2e-20 73.0 3.0 1.2e-11 44.9 1.9 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CEP17844.1 - 8.5e-15 54.3 7.3 6e-08 32.4 1.9 3.4 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEP17844.1 - 8.5e-08 32.5 0.4 3.1e-05 24.2 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CEP17844.1 - 2.2e-07 31.1 0.1 0.0072 16.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 CEP17844.1 - 1.6e-05 24.9 0.6 0.005 16.8 0.6 3.1 1 1 0 1 1 1 1 Caleosin related protein EF-hand_4 PF12763.7 CEP17844.1 - 0.00028 20.8 1.0 0.029 14.3 0.4 2.5 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CEP17844.1 - 0.00037 20.6 2.5 3.6 7.9 0.8 3.5 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_14 PF17959.1 CEP17844.1 - 0.0054 17.0 0.3 0.14 12.5 0.0 2.4 1 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CEP17845.1 - 2.9e-33 110.9 17.0 1.3e-08 33.8 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP17845.1 - 2.2e-31 108.1 8.3 1.9e-15 57.1 0.9 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP17845.1 - 1.9e-26 89.7 9.3 3.3e-08 32.8 0.0 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CEP17845.1 - 7.9e-22 76.9 13.1 2.7e-11 43.1 0.8 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CEP17845.1 - 1.5e-19 68.5 13.9 1.3e-05 24.5 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CEP17845.1 - 3.7e-12 46.4 1.1 5.7e-08 33.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CEP17845.1 - 4.4e-05 23.4 4.8 0.017 15.1 0.3 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CEP17845.1 - 4.5e-05 23.7 2.2 0.12 12.7 0.1 2.5 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CEP17845.1 - 0.00022 22.1 0.3 0.082 13.8 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 CEP17845.1 - 0.0004 20.4 0.2 0.0011 19.0 0.2 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DNA_pol_A_exo1 PF01612.20 CEP17845.1 - 0.00054 19.7 0.0 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease UCH PF00443.29 CEP17847.1 - 4.8e-41 140.9 0.0 8.7e-41 140.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP17847.1 - 9.4e-09 35.3 4.9 1.9e-07 31.0 4.9 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L38e PF01781.18 CEP17848.1 - 2.1e-33 114.2 4.0 2.3e-33 114.1 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_NTD2 PF04494.15 CEP17848.1 - 0.01 16.1 0.3 0.012 15.9 0.3 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain CLTH PF10607.9 CEP17849.1 - 8.1e-15 55.0 0.7 1.6e-14 54.0 0.7 1.5 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Clathrin_H_link PF13838.6 CEP17849.1 - 0.013 15.4 0.2 0.11 12.5 0.0 2.2 1 1 1 2 2 2 0 Clathrin-H-link MFS_1 PF07690.16 CEP17850.1 - 2.5e-30 105.6 83.1 1e-27 97.0 53.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CEP17851.1 - 1.8e-72 243.9 0.0 2.2e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17851.1 - 3e-33 115.2 0.0 4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP17851.1 - 2.4e-05 23.8 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP17851.1 - 0.2 10.6 0.0 0.2 10.6 0.0 2.2 3 0 0 3 3 3 0 Haspin like kinase domain eRF1_2 PF03464.15 CEP17852.1 - 4.5e-44 150.0 0.0 7e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CEP17852.1 - 1.1e-36 125.7 0.0 2.3e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CEP17852.1 - 3.1e-18 66.0 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CEP17852.1 - 5.4e-09 36.4 0.0 1.2e-08 35.3 0.0 1.6 2 0 0 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CEP17852.1 - 7.9e-09 35.9 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 MDM10 PF12519.8 CEP17853.1 - 5.3e-95 319.0 7.7 2.8e-86 290.2 5.0 2.3 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 CEP17853.1 - 6.4e-07 29.1 0.0 0.00021 20.9 0.0 2.5 3 0 0 3 3 3 2 Eukaryotic porin Cpn60_TCP1 PF00118.24 CEP17854.1 - 6.7e-155 516.4 19.1 7.6e-155 516.3 19.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CEP17854.1 - 0.00036 20.1 0.4 0.0026 17.3 0.1 2.2 2 0 0 2 2 2 1 Telomere recombination SCAB_CC PF16712.5 CEP17854.1 - 0.009 15.9 1.6 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Coiled-coil regions of plant-specific actin-binding protein DUF2536 PF10750.9 CEP17854.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) UQ_con PF00179.26 CEP17855.1 - 6.4e-21 74.5 0.1 9.7e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Importin_rep PF18773.1 CEP17855.1 - 0.0089 15.7 0.0 0.03 14.0 0.0 1.9 1 0 0 1 1 1 1 Importin 13 repeat RWD PF05773.22 CEP17855.1 - 0.015 15.6 0.2 0.025 14.8 0.2 1.5 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 CEP17855.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HSP70 PF00012.20 CEP17856.1 - 5.8e-07 28.1 0.0 2.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.20 CEP17856.1 - 0.11 12.0 0.1 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ribosomal_L6 PF00347.23 CEP17857.1 - 1.2e-33 115.6 7.9 1e-19 71.0 2.9 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 UPF0176_N PF17773.1 CEP17858.1 - 1.2e-16 60.8 0.0 2.4e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CEP17858.1 - 1.2e-15 57.6 12.7 3.1e-15 56.3 12.7 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 CEP17858.1 - 9.8e-08 32.5 0.0 2.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain zf_ZIC PF18366.1 CEP17858.1 - 0.36 11.0 2.7 0.41 10.8 0.2 2.5 3 0 0 3 3 3 0 Zic proteins zinc finger domain BALF1 PF06861.11 CEP17859.1 - 0.16 11.6 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 BALF1 protein Ribosomal_L16 PF00252.18 CEP17860.1 - 1.7e-44 151.0 0.1 2e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Velvet PF11754.8 CEP17861.1 - 7.1e-56 189.9 0.7 5.2e-33 115.0 0.1 2.3 1 1 1 2 2 2 2 Velvet factor DUF2076 PF09849.9 CEP17862.1 - 7e-05 23.0 9.9 8e-05 22.8 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 CEP17862.1 - 0.16 12.6 11.9 0.18 12.5 11.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2415 PF10313.9 CEP17863.1 - 4.7e-15 55.2 0.5 6.6e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 CEP17863.1 - 1e-07 32.2 0.0 0.71 10.2 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CEP17863.1 - 1.5e-06 28.8 10.5 0.018 15.9 0.6 4.7 6 1 0 6 6 6 3 WD domain, G-beta repeat Lgl_C PF08596.10 CEP17863.1 - 0.071 11.8 0.0 0.19 10.4 0.0 1.7 1 1 1 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal BBS2_Mid PF14783.6 CEP17863.1 - 0.12 12.4 0.0 27 4.9 0.0 2.6 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region SARS_X4 PF08779.10 CEP17863.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 SARS coronavirus X4 like WD40 PF00400.32 CEP17864.1 - 6.9e-26 90.0 18.9 1.6e-05 25.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17864.1 - 1.1e-11 44.8 1.2 0.0031 17.8 0.1 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CEP17864.1 - 0.009 14.1 0.8 0.016 13.2 0.8 1.3 1 0 0 1 1 1 1 IKI3 family MFS_1 PF07690.16 CEP17865.1 - 2.3e-15 56.4 21.5 1.2e-14 54.0 21.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2953 PF11167.8 CEP17865.1 - 3.3 7.9 6.0 1.2 9.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Asp_protease_2 PF13650.6 CEP17866.1 - 0.00017 22.1 0.0 0.00041 20.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP17866.1 - 0.0024 18.4 0.1 0.0054 17.3 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 CEP17866.1 - 0.014 15.6 3.6 0.31 11.3 1.9 2.8 2 1 0 2 2 2 0 Retrotransposon gag protein Haem_bd PF14376.6 CEP17867.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain FAM219A PF15260.6 CEP17867.1 - 9.4 6.6 7.5 11 6.4 5.1 2.0 1 1 1 2 2 2 0 Protein family FAM219A RT_RNaseH PF17917.1 CEP17868.1 - 3e-19 69.3 0.0 6.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP17868.1 - 1.1e-17 63.9 0.0 4.9e-13 49.0 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP17868.1 - 1.6e-15 57.3 0.0 3.7e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CEP17868.1 - 2.5e-08 33.9 5.5 0.00026 21.0 0.5 2.6 2 0 0 2 2 2 2 Integrase zinc binding domain rve_3 PF13683.6 CEP17868.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.27 CEP17869.1 - 5.7e-18 65.2 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP17869.1 - 6.5e-15 55.0 0.2 1.9e-14 53.5 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP17869.1 - 3.9e-14 52.8 0.0 1e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CEP17869.1 - 0.024 14.4 0.3 0.089 12.6 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 CEP17869.1 - 0.18 12.1 0.1 0.52 10.6 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger Methyltransf_25 PF13649.6 CEP17870.1 - 1.7e-10 41.5 0.0 4.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP17870.1 - 3.9e-10 40.3 0.0 1.5e-09 38.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP17870.1 - 1.6e-06 28.0 0.0 2.4e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP17870.1 - 2.5e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CEP17870.1 - 1.7e-05 24.8 0.0 3.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 CEP17870.1 - 5.6e-05 22.6 0.0 0.00055 19.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP17870.1 - 0.0004 21.1 0.0 0.044 14.5 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Lipase3_N PF03893.16 CEP17870.1 - 0.039 14.0 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipase 3 N-terminal region Methyltransf_4 PF02390.17 CEP17870.1 - 0.089 12.2 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase NST1 PF13945.6 CEP17870.1 - 0.53 10.4 4.9 0.77 9.8 4.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DNA_pol_A_exo1 PF01612.20 CEP17871.1 - 1.4e-11 44.4 0.1 6.9e-10 38.9 0.1 2.5 2 0 0 2 2 2 1 3'-5' exonuclease SLC12 PF03522.15 CEP17871.1 - 1.1 8.2 12.5 3.1 6.7 12.5 1.7 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CEP17871.1 - 1.4 7.8 19.9 0.15 11.0 14.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 CEP17871.1 - 1.6 7.5 10.8 3.1 6.5 10.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter CAF1 PF04857.20 CEP17871.1 - 2.3 7.3 11.2 0.66 9.1 0.0 2.5 2 0 0 2 2 2 0 CAF1 family ribonuclease TFIIA PF03153.13 CEP17871.1 - 3.9 7.4 59.2 0.13 12.2 24.4 3.3 2 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CEP17872.1 - 1.7e-15 56.6 18.2 9.2e-08 32.2 0.6 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP17872.1 - 6.6e-14 51.5 22.5 2.2e-05 24.7 3.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP17872.1 - 1.4e-09 37.9 21.0 0.00078 20.1 3.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP17872.1 - 9.2e-08 31.9 18.2 0.0051 16.8 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 CEP17872.1 - 0.0004 20.8 15.5 0.0012 19.2 1.2 3.8 1 1 2 3 3 3 1 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 CEP17872.1 - 0.0004 20.3 4.7 0.0021 18.0 0.9 2.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid TSC22 PF01166.18 CEP17872.1 - 0.0024 18.2 3.6 0.14 12.5 1.1 2.5 1 1 1 2 2 2 1 TSC-22/dip/bun family zf-C2H2_jaz PF12171.8 CEP17872.1 - 0.024 14.9 12.1 1.3 9.4 1.8 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding APC_N_CC PF16689.5 CEP17872.1 - 0.032 14.3 5.6 0.072 13.2 5.6 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain zf_C2H2_ZHX PF18387.1 CEP17872.1 - 0.034 13.8 13.2 0.51 10.0 0.1 3.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain ZapB PF06005.12 CEP17872.1 - 0.042 14.3 2.1 0.042 14.3 2.1 1.8 2 0 0 2 2 1 0 Cell division protein ZapB GAGA PF09237.11 CEP17872.1 - 0.044 13.6 5.1 2.2 8.2 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zf_UBZ PF18439.1 CEP17872.1 - 0.067 12.8 7.0 0.48 10.1 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CEP17872.1 - 0.12 12.5 8.5 2.1 8.5 2.3 3.0 1 1 2 3 3 3 0 Zinc ribbon domain bZIP_1 PF00170.21 CEP17872.1 - 0.2 11.8 2.7 0.47 10.6 2.0 1.9 1 1 1 2 2 2 0 bZIP transcription factor zf_ZIC PF18366.1 CEP17872.1 - 0.21 11.7 5.5 2.4 8.4 0.2 3.4 1 1 2 3 3 3 0 Zic proteins zinc finger domain zf-C2HC_2 PF13913.6 CEP17872.1 - 0.22 11.5 0.0 0.22 11.5 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-MYST PF17772.1 CEP17872.1 - 0.27 10.9 3.7 54 3.5 0.0 3.2 2 1 1 3 3 3 0 MYST family zinc finger domain zf-BED PF02892.15 CEP17872.1 - 0.3 11.1 5.9 0.092 12.8 1.1 2.7 1 1 1 2 2 2 0 BED zinc finger Herpes_BLRF2 PF05812.12 CEP17872.1 - 0.58 10.3 5.8 11 6.1 0.3 2.8 2 1 1 3 3 2 0 Herpesvirus BLRF2 protein PHD PF00628.29 CEP17872.1 - 0.65 9.9 8.9 6.5 6.7 3.6 2.8 2 1 0 2 2 2 0 PHD-finger zinc_ribbon_15 PF17032.5 CEP17872.1 - 0.89 10.4 6.5 15 6.4 6.5 2.3 1 1 0 1 1 1 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 CEP17872.1 - 1.1 9.3 7.0 31 4.7 7.0 2.6 1 1 0 1 1 1 0 zinc-ribbons HypA PF01155.19 CEP17872.1 - 1.1 9.2 4.1 7 6.7 3.9 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 CEP17872.1 - 1.2 9.4 17.7 0.46 10.7 1.0 3.4 1 1 2 3 3 3 0 AN1-like Zinc finger bZIP_2 PF07716.15 CEP17872.1 - 2 8.5 4.5 0.8 9.8 1.4 1.9 2 0 0 2 2 2 0 Basic region leucine zipper zf-trcl PF13451.6 CEP17872.1 - 4.9 7.1 7.4 64 3.6 4.1 3.1 2 1 0 2 2 2 0 Probable zinc-ribbon domain C1_4 PF07975.12 CEP17872.1 - 8.7 6.7 12.4 62 3.9 0.7 2.7 1 1 3 4 4 4 0 TFIIH C1-like domain DZR PF12773.7 CEP17872.1 - 9.1 6.4 10.4 15 5.7 8.0 2.4 2 1 0 2 2 1 0 Double zinc ribbon E1-E2_ATPase PF00122.20 CEP17873.1 - 6.9e-50 169.1 0.8 6.9e-50 169.1 0.8 3.6 3 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP17873.1 - 1.3e-47 161.8 8.1 1.3e-47 161.8 8.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEP17873.1 - 2.4e-22 80.3 0.8 2.4e-22 80.3 0.8 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP17873.1 - 2.5e-18 66.0 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEP17873.1 - 2.5e-17 62.3 0.1 5.3e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP17873.1 - 1.2e-07 31.7 1.8 9.9e-07 28.7 1.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP17873.1 - 6e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA_lig_CPD PF08302.11 CEP17873.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Thymidylate_kin PF02223.17 CEP17874.1 - 9.1e-50 168.9 0.0 1.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 CEP17874.1 - 0.011 16.3 0.1 0.028 15.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 CEP17874.1 - 0.019 15.2 0.1 0.037 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEP17874.1 - 0.04 14.3 0.2 0.3 11.5 0.1 2.5 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 CEP17874.1 - 0.053 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 CEP17874.1 - 0.064 12.7 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DLIC PF05783.11 CEP17875.1 - 3.7e-63 214.0 23.0 7.9e-53 179.9 5.7 4.9 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CEP17875.1 - 0.00065 20.1 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CEP17875.1 - 0.002 18.7 0.0 0.0047 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP17875.1 - 0.0034 17.7 0.0 0.068 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEP17875.1 - 0.012 16.2 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CEP17875.1 - 0.013 15.2 0.0 0.063 13.0 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP17875.1 - 0.032 14.1 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 CEP17875.1 - 0.039 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CEP17875.1 - 0.067 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.23 CEP17875.1 - 0.099 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 CEP17875.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CEP17875.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 NTPase FSA_C PF10479.9 CEP17875.1 - 9.7 4.2 8.7 6.3 4.8 2.1 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus DUF2459 PF09601.10 CEP17876.1 - 0.047 13.5 0.5 0.084 12.7 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2459) KilA-N PF04383.13 CEP17877.1 - 0.00057 19.7 0.3 0.0032 17.3 0.0 2.4 2 1 0 2 2 2 1 KilA-N domain Sacchrp_dh_C PF16653.5 CEP17880.1 - 1.9e-84 283.9 0.0 9.2e-84 281.7 0.0 2.1 3 0 0 3 3 3 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 CEP17880.1 - 6e-31 107.5 0.1 3.5e-30 105.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 CEP17880.1 - 1.3e-21 77.3 0.3 2.8e-21 76.1 0.3 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Trypsin PF00089.26 CEP17880.1 - 6.3e-11 42.5 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin AlaDh_PNT_C PF01262.21 CEP17880.1 - 3.8e-06 26.4 0.1 0.00023 20.5 0.0 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CEP17880.1 - 9.8e-06 25.7 0.3 2.3e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 CEP17880.1 - 0.0023 18.3 0.1 0.009 16.4 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CEP17880.1 - 0.0049 16.8 0.3 0.011 15.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 CEP17880.1 - 0.0053 16.9 0.3 0.011 15.9 0.3 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 CEP17880.1 - 0.0076 16.7 0.3 0.02 15.3 0.3 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_3 PF03447.16 CEP17880.1 - 0.08 13.6 0.7 0.27 11.9 0.7 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DUF5121 PF17165.4 CEP17881.1 - 0.11 12.9 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) DNA_pol_phi PF04931.13 CEP17882.1 - 0.2 9.7 5.8 0.32 9.1 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi MT-A70 PF05063.14 CEP17883.1 - 9.1e-26 90.8 1.7 1.5e-25 90.1 1.7 1.3 1 0 0 1 1 1 1 MT-A70 Glucosamine_iso PF01182.20 CEP17884.1 - 5.6e-22 78.7 0.0 8.1e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DEAD PF00270.29 CEP17884.1 - 0.087 12.6 0.1 0.21 11.4 0.2 1.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DAHP_synth_1 PF00793.20 CEP17885.1 - 5.1e-100 333.9 0.1 5.9e-100 333.7 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DMT_YdcZ PF04657.13 CEP17886.1 - 9e-17 61.7 5.6 1.3e-16 61.1 5.6 1.3 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ NDC10_II PF16787.5 CEP17888.1 - 9.7e-56 189.1 0.2 1.7e-55 188.3 0.2 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP17888.1 - 6.7e-15 55.2 0.4 2.6e-14 53.3 0.4 2.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SWC7 PF17330.2 CEP17888.1 - 0.077 13.1 2.4 0.14 12.2 0.1 2.6 2 1 1 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Knl1_RWD_C PF18210.1 CEP17888.1 - 0.14 12.6 0.9 0.49 10.9 0.2 2.3 2 0 0 2 2 2 0 Knl1 RWD C-terminal domain Vps39_2 PF10367.9 CEP17889.1 - 1.3e-16 60.9 0.3 5.8e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CEP17889.1 - 2.7e-16 59.8 2.2 4.3e-14 52.7 0.9 3.0 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 CEP17889.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CEP17889.1 - 0.0011 18.8 16.5 0.22 11.4 1.9 4.3 5 0 0 5 5 5 3 Region in Clathrin and VPS Cep57_CLD_2 PF14197.6 CEP17889.1 - 5.4 7.2 8.4 22 5.3 2.5 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Oxidored_q6 PF01058.22 CEP17890.1 - 2.3e-22 79.2 0.1 3.5e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Gram_pos_anchor PF00746.21 CEP17891.1 - 0.025 14.5 1.7 0.066 13.2 1.7 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TrbC PF04956.13 CEP17891.1 - 0.18 12.0 3.3 0.52 10.6 3.1 1.9 1 1 0 1 1 1 0 TrbC/VIRB2 family Gly-zipper_Omp PF13488.6 CEP17891.1 - 0.86 9.6 12.4 1.4 9.0 12.4 1.2 1 0 0 1 1 1 0 Glycine zipper Baculo_11_kDa PF06143.11 CEP17892.1 - 0.0034 16.9 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Baculovirus 11 kDa family DctQ PF04290.12 CEP17892.1 - 0.0078 16.1 0.1 0.0086 16.0 0.1 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component LysE PF01810.18 CEP17892.1 - 0.048 13.1 0.0 0.055 12.9 0.0 1.0 1 0 0 1 1 1 0 LysE type translocator Ribosomal_S3_C PF00189.20 CEP17893.1 - 1.8e-22 79.7 1.2 6.1e-22 77.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CEP17893.1 - 1.3e-12 47.3 0.1 2.4e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CEP17893.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Metallophos PF00149.28 CEP17894.1 - 1.3e-33 117.3 0.3 1.7e-33 116.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP17894.1 - 0.032 14.7 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain VPS28 PF03997.12 CEP17895.1 - 0.084 12.5 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 VPS28 protein Asp_protease_2 PF13650.6 CEP17896.1 - 0.1 13.2 0.0 1.7 9.3 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease RVT_1 PF00078.27 CEP17897.1 - 1.1e-11 44.7 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pil1 PF13805.6 CEP17899.1 - 1.5e-39 136.1 1.8 1.5e-39 136.1 1.8 2.0 2 0 0 2 2 2 1 Eisosome component PIL1 BLOC1_2 PF10046.9 CEP17899.1 - 0.0048 17.2 2.8 0.016 15.5 2.5 2.1 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 CEP17899.1 - 0.011 16.2 7.1 0.43 11.0 0.2 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Phage_GP20 PF06810.11 CEP17899.1 - 0.033 14.0 2.4 0.091 12.6 0.7 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 PCRF PF03462.18 CEP17899.1 - 0.058 13.3 0.3 0.17 11.7 0.3 1.9 1 0 0 1 1 1 0 PCRF domain Baculo_PEP_C PF04513.12 CEP17899.1 - 0.089 12.8 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 CEP17899.1 - 0.13 11.6 0.8 0.27 10.5 0.8 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_23 PF13476.6 CEP17899.1 - 1 9.8 10.8 3.8 7.9 1.8 2.3 2 0 0 2 2 2 0 AAA domain RAI16-like PF10257.9 CEP17900.1 - 1.4e-71 241.3 0.2 2.9e-71 240.2 0.2 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein IATP PF04568.12 CEP17900.1 - 4 7.9 4.6 10 6.6 4.6 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF966 PF06136.13 CEP17901.1 - 0.0026 17.6 0.1 0.0032 17.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF966) p450 PF00067.22 CEP17903.1 - 1.3e-54 185.7 0.0 1.7e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_54 PF04666.13 CEP17904.1 - 0.13 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MFS_1 PF07690.16 CEP17907.1 - 2e-13 50.0 0.2 2.2e-13 49.9 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CEP17907.1 - 0.003 16.5 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 MFS_1 like family OATP PF03137.20 CEP17907.1 - 0.011 14.1 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4199 PF13858.6 CEP17907.1 - 0.013 15.9 0.1 0.036 14.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1772 PF08592.11 CEP17907.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3382 PF11862.8 CEP17907.1 - 0.046 14.0 0.6 0.078 13.3 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3382) Forkhead PF00250.18 CEP17908.1 - 8.4e-34 115.7 0.1 2.4e-33 114.3 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain SUIM_assoc PF16619.5 CEP17908.1 - 0.52 10.4 15.4 1.1 9.4 9.1 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NIF PF03031.18 CEP17909.1 - 1e-46 158.6 0.0 1.7e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Adaptin_binding PF10199.9 CEP17909.1 - 0.08 13.5 3.2 0.063 13.9 0.7 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4199 PF13858.6 CEP17909.1 - 5.7 7.3 5.9 14 6.0 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Glucan_synthase PF02364.15 CEP17910.1 - 0 1299.3 0.0 0 1297.8 0.0 1.7 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEP17910.1 - 8.4e-32 110.2 1.3 8.4e-32 110.2 1.3 2.9 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2448 PF10476.9 CEP17910.1 - 0.04 13.8 0.1 0.19 11.6 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) SPC22 PF04573.12 CEP17910.1 - 0.89 9.0 3.9 0.56 9.7 0.1 2.5 2 1 0 2 2 2 0 Signal peptidase subunit DUF629 PF04780.12 CEP17911.1 - 0.00078 18.1 4.3 0.35 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zinc_ribbon_15 PF17032.5 CEP17911.1 - 0.0082 16.9 3.2 0.92 10.3 0.1 2.5 3 0 0 3 3 3 2 zinc-ribbon family zf-C2H2 PF00096.26 CEP17911.1 - 0.019 15.4 0.6 0.019 15.4 0.6 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 CEP17911.1 - 0.047 14.1 0.8 0.047 14.1 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 CEP17911.1 - 0.11 11.7 1.3 0.27 10.4 1.3 1.6 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 CEP17911.1 - 0.14 12.6 6.3 0.99 9.8 5.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CEP17911.1 - 0.22 12.5 0.5 0.22 12.5 0.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP17911.1 - 0.51 10.7 0.2 0.51 10.7 0.2 3.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF155 PF02582.14 CEP17912.1 - 4.8e-55 186.4 0.2 4.8e-55 186.4 0.2 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 PRIMA1 PF16101.5 CEP17912.1 - 2.8 8.0 4.6 7.9 6.6 4.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Arf PF00025.21 CEP17913.1 - 1.8e-71 239.2 0.4 2e-71 239.0 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP17913.1 - 7.9e-13 48.7 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEP17913.1 - 8.5e-13 48.2 1.0 1.1e-06 28.1 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CEP17913.1 - 1.7e-11 43.9 0.0 2.1e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEP17913.1 - 8.2e-11 41.7 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEP17913.1 - 1.5e-09 37.6 0.0 2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP17913.1 - 1.1e-07 31.9 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP17913.1 - 0.00028 20.5 0.0 0.0031 17.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 CEP17913.1 - 0.025 14.5 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 CEP17913.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CEP17913.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Aa_trans PF01490.18 CEP17914.1 - 2.1e-77 260.5 36.8 2.6e-77 260.3 36.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HCMV_UL139 PF12507.8 CEP17915.1 - 0.014 15.8 5.7 0.014 15.8 5.7 3.1 1 1 2 3 3 3 0 Human Cytomegalovirus UL139 protein HMMR_N PF15905.5 CEP17915.1 - 0.032 13.7 46.1 0.44 10.0 36.0 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HalX PF08663.10 CEP17915.1 - 0.19 12.0 0.3 0.19 12.0 0.3 4.1 4 0 0 4 4 4 0 HalX domain Macoilin PF09726.9 CEP17915.1 - 0.24 9.9 30.9 0.3 9.6 30.9 1.0 1 0 0 1 1 1 0 Macoilin family Mce4_CUP1 PF11887.8 CEP17915.1 - 0.36 10.2 5.8 0.13 11.7 0.8 2.4 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Fib_alpha PF08702.10 CEP17915.1 - 0.88 9.8 34.8 0.61 10.3 7.5 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CEP17915.1 - 1.7 9.0 38.5 3 8.2 29.2 2.8 1 1 2 3 3 3 0 Fez1 HIP1_clath_bdg PF16515.5 CEP17915.1 - 2.3 8.9 46.5 2.9 8.5 9.9 3.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 CEP17915.1 - 3.1 7.3 40.6 26 4.3 13.4 2.7 1 1 0 2 2 2 0 Intermediate filament protein DUF4889 PF16230.5 CEP17915.1 - 3.5 7.9 6.5 0.77 10.0 0.4 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4889) Flagellar_rod PF05149.12 CEP17915.1 - 8.4 5.8 36.0 0.18 11.2 2.8 3.2 1 1 2 3 3 3 0 Paraflagellar rod protein YtxH PF12732.7 CEP17915.1 - 9.9 6.8 20.7 6.3e+02 1.0 0.1 4.3 1 1 1 2 2 1 0 YtxH-like protein G-patch PF01585.23 CEP17916.1 - 4.7e-15 55.2 1.3 1.4e-14 53.7 1.3 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CEP17916.1 - 7.8e-07 29.1 1.5 7.8e-07 29.1 1.5 3.6 2 1 0 2 2 1 1 G-patch domain RR_TM4-6 PF06459.12 CEP17916.1 - 0.01 15.7 20.7 0.014 15.2 20.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.19 CEP17916.1 - 0.04 12.9 16.5 0.049 12.6 16.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 CEP17916.1 - 0.066 11.5 22.8 0.079 11.2 22.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 CEP17916.1 - 0.11 12.5 10.9 0.15 12.1 10.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region SOBP PF15279.6 CEP17916.1 - 0.13 12.9 10.9 0.16 12.6 10.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2052 PF09747.9 CEP17916.1 - 0.13 12.4 17.1 0.19 11.8 17.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.12 CEP17916.1 - 0.18 10.8 10.9 0.23 10.4 10.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PCM1_C PF15717.5 CEP17916.1 - 0.21 10.2 19.1 0.3 9.7 19.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Zip PF02535.22 CEP17916.1 - 0.33 10.1 10.8 0.48 9.6 10.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GET2 PF08690.10 CEP17916.1 - 0.52 9.9 20.5 5.2 6.6 16.9 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 SAPS PF04499.15 CEP17916.1 - 0.58 8.9 12.6 0.78 8.5 12.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rtf2 PF04641.12 CEP17916.1 - 0.7 9.2 29.3 1.2 8.5 29.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.16 CEP17916.1 - 0.95 9.5 8.4 1.2 9.1 8.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 CEP17916.1 - 0.96 7.5 15.7 1.2 7.2 15.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CEP17916.1 - 1 8.1 17.6 1.2 7.8 17.6 1.1 1 0 0 1 1 1 0 Presenilin O-antigen_lig PF13425.6 CEP17916.1 - 1.7 7.4 12.6 2.2 7.0 12.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NPR3 PF03666.13 CEP17916.1 - 1.7 7.4 20.7 2.1 7.0 20.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.8 CEP17916.1 - 1.7 9.0 9.6 2.3 8.6 9.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SLC12 PF03522.15 CEP17916.1 - 2.9 6.8 20.5 3.9 6.4 20.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CEP17916.1 - 3.4 4.7 12.8 3.6 4.6 12.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2151 PF10221.9 CEP17916.1 - 3.6 6.1 19.5 4.5 5.8 19.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator MCM_bind PF09739.9 CEP17916.1 - 3.9 5.8 19.3 4.8 5.5 19.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4551 PF15087.6 CEP17916.1 - 4.4 6.0 12.4 5.2 5.8 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sec62 PF03839.16 CEP17916.1 - 4.5 6.7 25.0 8.7 5.8 25.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 CEP17916.1 - 4.8 5.9 14.9 5.7 5.7 14.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAP1 PF08601.10 CEP17917.1 - 4.2e-10 39.9 11.9 1.4e-09 38.1 0.4 2.1 1 1 1 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 CEP17917.1 - 1.6e-08 34.5 18.0 6.1e-07 29.5 18.0 2.6 1 1 0 1 1 1 1 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 CEP17917.1 - 0.014 15.6 5.5 0.026 14.8 5.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.15 CEP17917.1 - 0.077 13.1 22.2 0.23 11.6 13.7 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Ribosomal_L10 PF00466.20 CEP17917.1 - 0.13 12.4 1.4 0.26 11.5 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein L10 DUF5320 PF17253.2 CEP17917.1 - 0.32 12.1 1.8 0.72 11.0 1.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) NYD-SP28_assoc PF14775.6 CEP17917.1 - 0.34 11.0 2.3 0.53 10.4 1.2 1.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain PV-1 PF06637.11 CEP17917.1 - 1.3 7.8 11.4 0.58 8.9 8.7 1.6 1 1 1 2 2 2 0 PV-1 protein (PLVAP) Globin PF00042.22 CEP17918.1 - 1.5e-06 28.7 0.2 0.005 17.4 0.0 2.7 3 0 0 3 3 3 2 Globin DER1 PF04511.15 CEP17919.1 - 2.9e-28 99.1 1.1 3.4e-28 98.9 1.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF2207 PF09972.9 CEP17919.1 - 0.53 9.0 2.8 0.82 8.4 2.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SIR2 PF02146.17 CEP17921.1 - 2.1e-60 203.6 0.0 3.7e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family IFT46_B_C PF12317.8 CEP17921.1 - 9 6.0 10.2 30 4.3 0.2 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal UPF0121 PF03661.13 CEP17922.1 - 2.1e-41 141.9 7.7 2.5e-41 141.7 7.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Peptidase_M1 PF01433.20 CEP17923.1 - 2.5e-84 282.2 1.1 4.2e-84 281.5 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CEP17923.1 - 1.7e-81 274.2 1.5 3.5e-81 273.2 0.2 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CEP17923.1 - 6.7e-53 179.6 5.9 1.8e-51 175.0 0.7 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain DUF2808 PF10989.8 CEP17923.1 - 0.053 13.5 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Pro_isomerase PF00160.21 CEP17924.1 - 9.3e-50 169.0 0.3 2.1e-49 167.8 0.1 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CEP17924.1 - 4.6e-08 33.6 1.1 0.014 16.2 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP17924.1 - 0.0013 19.0 0.0 0.39 11.0 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS1 PF14779.6 CEP17924.1 - 0.044 13.2 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 BAG6 PF12057.8 CEP17925.1 - 0.15 11.7 5.2 0.19 11.4 0.1 3.0 2 1 1 3 3 3 0 BCL2-associated athanogene 6 GEN1_C PF18380.1 CEP17925.1 - 0.32 11.9 0.2 0.32 11.9 0.2 2.6 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pkinase PF00069.25 CEP17926.1 - 6e-77 258.6 0.0 9.1e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP17926.1 - 1e-44 152.8 0.0 1.5e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP17926.1 - 3e-09 36.6 0.0 4.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP17926.1 - 2.2e-06 26.9 0.1 4e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CEP17926.1 - 0.0054 16.7 1.7 0.0067 16.4 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEP17926.1 - 0.0069 15.8 0.7 0.012 15.0 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ntox14 PF15522.6 CEP17926.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 14 DnaJ PF00226.31 CEP17927.1 - 8e-07 29.1 0.1 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CEP17927.1 - 0.0056 16.7 0.0 0.0056 16.7 0.0 1.2 1 1 0 1 1 1 1 Pam16 DUF5353 PF17304.2 CEP17927.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Peptidase_M24 PF00557.24 CEP17928.1 - 2.2e-22 79.8 0.2 2.8e-22 79.5 0.2 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Atg29_N PF18388.1 CEP17929.1 - 1.2e-13 50.6 1.4 4e-13 49.0 1.4 1.9 1 1 0 1 1 1 1 Atg29 N-terminal domain Myb_DNA-bind_6 PF13921.6 CEP17929.1 - 0.0035 17.6 0.4 0.01 16.0 0.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2111 PF09884.9 CEP17929.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) HLH PF00010.26 CEP17930.1 - 1.6e-12 47.2 0.3 5.3e-12 45.5 0.3 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UspA1_rep PF18792.1 CEP17931.1 - 0.15 12.6 0.3 0.46 11.1 0.3 1.9 1 0 0 1 1 1 0 Ubiquitous surface protein adhesin repeat Radical_SAM PF04055.21 CEP17932.1 - 9.5e-19 68.4 0.0 2.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 CEP17932.1 - 0.00064 19.7 0.8 0.0026 17.8 0.1 2.5 4 0 0 4 4 4 1 HemN C-terminal domain ERO1 PF04137.15 CEP17933.1 - 5.5e-134 446.8 0.4 6.6e-134 446.6 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ResIII PF04851.15 CEP17934.1 - 6.8e-24 84.8 0.4 1.2e-22 80.7 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CEP17934.1 - 1.2e-18 67.4 0.1 4.2e-18 65.7 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP17934.1 - 4.8e-15 55.8 0.0 2.1e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Actin PF00022.19 CEP17935.1 - 3.6e-152 506.7 0.0 1.4e-151 504.8 0.0 1.7 1 1 0 1 1 1 1 Actin TAF PF02969.17 CEP17936.1 - 0.0066 16.6 0.8 0.011 15.9 0.8 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) GshA PF08886.11 CEP17936.1 - 0.045 12.3 0.2 0.055 12.0 0.2 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase HAND PF09110.11 CEP17936.1 - 4 8.2 11.3 1.6 9.5 2.2 2.1 1 1 1 2 2 2 0 HAND PHD PF00628.29 CEP17937.1 - 2.3e-07 30.6 9.1 4.8e-07 29.6 9.1 1.6 1 0 0 1 1 1 1 PHD-finger SPRY PF00622.28 CEP17937.1 - 2.7e-06 27.5 0.0 6.7e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 SPRY domain tRNA-synt_2 PF00152.20 CEP17938.1 - 1.8e-79 267.1 0.3 2.3e-79 266.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEP17938.1 - 1.3e-12 47.6 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CEP17938.1 - 2.9e-08 33.5 0.1 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TFIIE-A_C PF11521.8 CEP17938.1 - 0.096 13.0 0.4 1.6 9.1 0.0 2.9 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha Ribosomal_60s PF00428.19 CEP17938.1 - 0.57 10.8 9.0 1.4 9.5 9.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein PPR_2 PF13041.6 CEP17939.1 - 1e-12 48.0 0.5 0.022 14.9 0.0 6.0 5 2 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 CEP17939.1 - 1.2e-11 44.5 1.0 0.00013 22.0 0.1 4.5 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 CEP17939.1 - 4e-08 33.0 0.4 0.015 15.5 0.1 6.5 8 0 0 8 8 8 1 PPR repeat PPR_long PF17177.4 CEP17939.1 - 2.9e-07 30.0 2.4 0.011 15.1 0.0 3.2 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 CEP17939.1 - 0.00021 21.7 0.2 0.066 13.6 0.1 2.6 2 0 0 2 2 2 1 Bacterial transcriptional activator domain MNE1 PF13762.6 CEP17939.1 - 0.00043 20.3 0.1 0.048 13.6 0.0 2.9 3 1 1 4 4 4 1 Mitochondrial splicing apparatus component TPR_19 PF14559.6 CEP17939.1 - 0.0006 20.3 1.3 0.13 12.8 0.7 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17939.1 - 0.0014 19.3 0.1 1.1 10.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.7 CEP17939.1 - 0.024 14.3 0.1 15 5.4 0.0 4.1 4 0 0 4 4 4 0 PPR repeat TPR_8 PF13181.6 CEP17939.1 - 0.096 12.9 2.2 1.6 9.1 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Septin PF00735.18 CEP17940.1 - 5.9e-107 357.1 0.0 5.9e-107 357.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEP17940.1 - 7.4e-06 26.0 0.0 4.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP17940.1 - 0.0043 16.6 0.1 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain tRNA_synthFbeta PF17759.1 CEP17940.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain RF-1 PF00472.20 CEP17940.1 - 0.018 15.0 1.1 0.092 12.7 0.9 2.2 2 0 0 2 2 2 0 RF-1 domain Dynamin_N PF00350.23 CEP17940.1 - 0.32 11.0 2.9 1.1 9.3 0.1 2.6 2 1 1 3 3 3 0 Dynamin family DUF4140 PF13600.6 CEP17940.1 - 3.5 8.1 7.0 77 3.8 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ras PF00071.22 CEP17941.1 - 1.7e-56 190.3 0.3 2.2e-56 189.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP17941.1 - 8.3e-38 129.3 0.1 1.5e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP17941.1 - 2.9e-17 62.7 0.2 3.7e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP17941.1 - 1.6e-07 31.1 0.1 7.9e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEP17941.1 - 1.5e-06 27.8 0.1 2.2e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEP17941.1 - 1.6e-05 24.9 0.1 2.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP17941.1 - 1.7e-05 24.3 0.2 2.3e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEP17941.1 - 7.5e-05 22.7 0.0 0.08 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CEP17941.1 - 0.0095 15.7 0.1 0.036 13.8 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 CEP17941.1 - 0.037 14.6 0.1 0.073 13.7 0.1 1.5 1 1 0 1 1 1 0 TIR domain AAA_7 PF12775.7 CEP17941.1 - 0.052 13.1 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 CEP17941.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Carn_acyltransf PF00755.20 CEP17942.1 - 8.2e-216 718.2 0.2 9.4e-216 718.0 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF563 PF04577.14 CEP17943.1 - 2.5e-08 34.3 0.0 4.4e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pox_F15 PF04596.12 CEP17943.1 - 0.0034 17.1 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Poxvirus protein F15 Ketoacyl-synt_2 PF13723.6 CEP17943.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain MGC-24 PF05283.11 CEP17944.1 - 0.78 10.2 10.1 0.93 9.9 10.1 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4820 PF16091.5 CEP17944.1 - 0.97 8.8 5.6 1.1 8.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2318 PF10080.9 CEP17945.1 - 0.05 13.7 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Lsr2 PF11774.8 CEP17946.1 - 0.035 14.2 0.5 0.09 12.9 0.1 1.8 1 1 1 2 2 2 0 Lsr2 S_tail_recep_bd PF14928.6 CEP17946.1 - 0.093 13.4 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain Cupin_8 PF13621.6 CEP17947.1 - 0.037 13.7 0.4 0.041 13.6 0.4 1.0 1 0 0 1 1 1 0 Cupin-like domain AIG1 PF04548.16 CEP17947.1 - 0.06 12.7 0.2 0.07 12.4 0.2 1.1 1 0 0 1 1 1 0 AIG1 family BCDHK_Adom3 PF10436.9 CEP17948.1 - 7.2e-67 224.3 0.1 1.1e-66 223.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CEP17948.1 - 7.4e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CEP17948.1 - 0.0007 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.17 CEP17948.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Gpi16 PF04113.14 CEP17949.1 - 1.2e-146 489.4 0.1 2.2e-145 485.3 0.1 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component NUDIX PF00293.28 CEP17950.1 - 0.00077 19.5 0.0 0.011 15.8 0.0 1.9 1 1 1 2 2 2 2 NUDIX domain MutS_IV PF05190.18 CEP17950.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 MutS family domain IV F-box-like PF12937.7 CEP17951.1 - 4.2e-09 36.2 0.0 1.4e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP17951.1 - 0.00013 21.7 0.0 0.00048 19.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain Terminase_3C PF17288.2 CEP17951.1 - 0.17 12.2 1.4 11 6.4 0.2 2.4 2 0 0 2 2 2 0 Terminase RNAseH like domain ING PF12998.7 CEP17952.1 - 2.7e-16 60.0 0.4 3.7e-16 59.5 0.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CEP17952.1 - 2.9e-05 23.9 7.9 4.8e-05 23.2 7.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CEP17952.1 - 0.02 15.1 0.5 0.038 14.2 0.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 CEP17952.1 - 0.054 13.1 2.5 0.11 12.1 2.5 1.5 1 0 0 1 1 1 0 PHD-finger DnaJ_C PF01556.18 CEP17953.1 - 2.2e-36 125.1 0.0 3.9e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP17953.1 - 2.4e-26 91.6 3.9 2.4e-26 91.6 3.9 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP17953.1 - 6.2e-08 32.9 22.5 1.3e-07 31.8 22.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 CEP17953.1 - 6.5e-05 22.9 0.5 6.5e-05 22.9 0.5 2.8 3 0 0 3 3 3 1 Cytochrome c7 and related cytochrome c Multi-haem_cyto PF13447.6 CEP17953.1 - 0.11 11.8 1.4 0.17 11.1 1.4 1.2 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH Cytochrom_CIII PF02085.16 CEP17953.1 - 2.6 8.4 10.7 0.4 11.0 4.5 2.4 2 0 0 2 2 2 0 Class III cytochrome C family Peptidase_S8 PF00082.22 CEP17954.1 - 3.6e-41 141.4 0.8 6.5e-41 140.5 0.8 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CEP17954.1 - 2.7e-24 85.0 0.8 5.9e-24 83.9 0.8 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CEP17954.1 - 0.0003 21.5 0.3 0.00088 20.0 0.3 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 CEP17954.1 - 0.051 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 N-terminal of Subtilase family E7 PF00527.18 CEP17955.1 - 2.6 8.3 10.4 17 5.7 10.4 2.2 1 1 0 1 1 1 0 E7 protein, Early protein LMBR1 PF04791.16 CEP17955.1 - 3.9 6.3 6.0 5.3 5.8 6.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_pol_A_exo1 PF01612.20 CEP17956.1 - 0.00024 20.9 0.0 0.0026 17.5 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease DUF2207 PF09972.9 CEP17957.1 - 0.07 11.9 0.1 0.074 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LapA_dom PF06305.11 CEP17957.1 - 0.74 9.7 7.5 1.5 8.6 7.5 1.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TPR_1 PF00515.28 CEP17958.1 - 1.8e-60 198.4 19.6 3.2e-08 33.0 0.0 10.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CEP17958.1 - 8.6e-53 172.3 19.3 1.2e-05 25.1 0.0 9.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 CEP17958.1 - 2.7e-42 139.4 16.3 8.1e-06 25.6 0.0 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 CEP17958.1 - 8.2e-31 104.1 10.4 0.00024 21.7 0.0 9.2 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 CEP17958.1 - 9.1e-30 100.9 15.7 0.00036 20.7 0.0 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 CEP17958.1 - 3e-29 101.4 6.2 4.4e-08 33.6 0.2 6.5 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 CEP17958.1 - 2.9e-27 94.7 22.7 6.1e-06 26.4 3.8 8.4 3 2 4 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 CEP17958.1 - 9.1e-26 90.2 16.5 2.4e-05 24.8 0.3 6.8 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 CEP17958.1 - 5.1e-25 85.6 11.1 0.00018 21.3 0.0 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 CEP17958.1 - 6.2e-24 83.0 14.1 0.023 15.3 1.5 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 CEP17958.1 - 4.7e-23 80.6 29.5 1.3e-05 24.8 0.5 8.8 4 2 4 8 8 8 7 TPR repeat TPR_9 PF13371.6 CEP17958.1 - 8.6e-17 61.1 11.8 0.0047 17.0 0.2 6.8 3 2 3 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.6 CEP17958.1 - 6.6e-15 55.1 11.0 0.013 14.7 0.0 5.7 2 1 4 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP17958.1 - 1.7e-08 34.5 17.0 9.3e-05 22.6 2.6 3.4 3 2 1 4 4 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CEP17958.1 - 2.4e-08 33.6 18.6 0.057 13.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 CEP17958.1 - 2.7e-06 27.2 8.0 0.0041 16.8 0.1 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 CEP17958.1 - 0.00032 20.2 6.5 0.18 11.1 0.0 3.8 1 1 1 3 3 3 2 MalT-like TPR region DUF2225 PF09986.9 CEP17958.1 - 0.00035 20.4 5.8 0.24 11.1 0.2 3.5 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 CEP17958.1 - 0.00038 20.0 15.6 0.45 9.9 1.6 4.7 1 1 3 4 4 4 3 Soluble NSF attachment protein, SNAP DUF627 PF04781.12 CEP17958.1 - 0.0046 16.9 3.9 0.64 10.1 0.3 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF627) MIT PF04212.18 CEP17958.1 - 0.0052 16.8 22.7 1.9 8.6 0.4 7.1 8 0 0 8 8 7 1 MIT (microtubule interacting and transport) domain Tcf25 PF04910.14 CEP17958.1 - 0.021 13.9 3.0 0.67 9.0 0.1 3.0 2 1 1 3 3 3 0 Transcriptional repressor TCF25 TPR_3 PF07720.12 CEP17958.1 - 0.03 14.3 18.6 5.5 7.1 0.6 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 CEP17958.1 - 0.056 12.4 1.4 17 4.3 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TipAS PF07739.13 CEP17958.1 - 0.067 13.7 5.2 3 8.4 0.6 3.8 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain Rapsyn_N PF10579.9 CEP17958.1 - 0.11 12.6 0.6 4.2 7.5 0.0 3.4 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TOM20_plant PF06552.12 CEP17958.1 - 0.38 10.5 7.6 12 5.6 0.1 4.4 4 2 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Cohesin_load PF10345.9 CEP17958.1 - 0.51 8.7 4.8 3.7 5.9 0.5 2.8 2 1 1 3 3 3 0 Cohesin loading factor TPR_20 PF14561.6 CEP17958.1 - 0.51 10.7 9.7 13 6.2 0.0 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF5344 PF17279.2 CEP17958.1 - 0.79 10.3 8.3 3.5 8.3 0.1 4.7 4 1 0 4 4 4 0 Family of unknown function (DUF5344) BTAD PF03704.17 CEP17958.1 - 1.9 8.9 11.5 7.9 6.9 0.2 3.8 3 2 1 5 5 4 0 Bacterial transcriptional activator domain Ribosomal_L13 PF00572.18 CEP17959.1 - 1.5e-53 180.3 0.1 1.8e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 OHCU_decarbox PF09349.10 CEP17960.1 - 2.1e-43 148.5 0.0 2.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase YuzL PF14115.6 CEP17960.1 - 0.098 13.2 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 YuzL-like protein Rft-1 PF04506.13 CEP17962.1 - 0.0058 15.4 0.1 0.006 15.4 0.1 1.2 1 0 0 1 1 1 1 Rft protein ERGIC_N PF13850.6 CEP17962.1 - 0.026 14.9 1.0 0.12 12.7 0.0 2.3 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MrpF_PhaF PF04066.13 CEP17962.1 - 2.2 8.8 8.0 2.6 8.5 1.4 2.6 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) MFS_1 PF07690.16 CEP17963.1 - 2.1e-11 43.4 2.1 2.1e-11 43.4 2.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP17963.1 - 0.0053 15.7 1.8 0.0055 15.6 1.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CEP17963.1 - 0.022 14.1 0.9 0.022 14.1 0.9 1.0 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Ras PF00071.22 CEP17964.1 - 1.9e-57 193.4 0.3 2.4e-57 193.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP17964.1 - 3.3e-37 127.3 0.1 5.3e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP17964.1 - 3.6e-16 59.1 0.1 4.6e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP17964.1 - 4e-06 26.5 0.1 2.2e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CEP17964.1 - 2.1e-05 24.0 0.1 2.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CEP17964.1 - 3.1e-05 24.0 0.0 5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP17964.1 - 7e-05 22.3 0.1 8.5e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEP17964.1 - 0.00019 21.4 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CEP17964.1 - 0.0022 17.8 0.0 0.0066 16.3 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CEP17964.1 - 0.035 13.6 0.1 0.69 9.4 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 CEP17964.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MULE PF10551.9 CEP17965.1 - 7.1e-17 61.6 0.5 1.7e-16 60.4 0.5 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CEP17965.1 - 0.0029 16.5 0.1 0.0046 15.9 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Rib_hydrolayse PF02267.17 CEP17966.1 - 3.5e-08 33.2 0.0 2.6e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosyl cyclase HLH PF00010.26 CEP17967.1 - 2.5e-08 33.7 1.6 2.5e-08 33.7 1.6 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2852 PF11014.8 CEP17967.1 - 1.5 9.0 6.1 0.34 11.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DDE_3 PF13358.6 CEP17968.1 - 1.5e-13 50.8 0.1 1e-09 38.3 0.0 2.1 1 1 0 2 2 2 2 DDE superfamily endonuclease PGM_PMM_I PF02878.16 CEP17968.1 - 0.047 13.4 0.1 0.66 9.7 0.0 2.3 1 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YjeF_N PF03853.15 CEP17970.1 - 3e-32 111.9 0.0 5.3e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CEP17970.1 - 6.6e-06 26.9 4.5 6.6e-06 26.9 4.5 2.2 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.7 CEP17970.1 - 0.00079 19.5 0.0 0.0026 17.8 0.0 1.9 1 1 0 1 1 1 1 Scd6-like Sm domain UPF0014 PF03649.13 CEP17971.1 - 2.4e-62 210.4 19.9 3.6e-62 209.9 19.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) DUF2457 PF10446.9 CEP17971.1 - 0.0046 16.2 13.1 0.0075 15.5 13.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) YL1 PF05764.13 CEP17971.1 - 0.0084 16.3 7.4 0.013 15.7 7.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 CEP17971.1 - 0.055 11.7 12.2 0.077 11.2 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CEP17971.1 - 0.088 12.2 13.2 0.13 11.7 13.2 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 CEP17971.1 - 0.75 8.3 8.0 1.1 7.7 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GREB1 PF15782.5 CEP17971.1 - 0.87 6.6 8.0 1.2 6.2 8.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CEP17971.1 - 0.97 7.6 9.1 1.3 7.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein APG6_N PF17675.1 CEP17972.1 - 0.049 14.2 32.5 0.033 14.7 20.2 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 CEP17972.1 - 0.057 12.3 36.4 0.013 14.4 9.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3141 PF11339.8 CEP17972.1 - 0.13 10.7 4.2 0.052 12.0 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3141) Pkinase PF00069.25 CEP17973.1 - 6.7e-23 81.4 0.0 1.5e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CEP17973.1 - 1.1e-06 27.7 0.0 2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEP17973.1 - 2.9e-05 23.5 0.0 0.00011 21.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PPR_3 PF13812.6 CEP17974.1 - 1e-37 128.0 12.5 4.6e-11 42.6 0.3 5.9 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 CEP17974.1 - 1.4e-33 114.9 8.7 5.7e-07 29.6 0.1 7.2 5 3 3 8 8 8 8 PPR repeat family PPR_long PF17177.4 CEP17974.1 - 6.1e-24 84.6 6.0 1.5e-08 34.2 0.0 4.2 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CEP17974.1 - 1.2e-13 50.2 11.5 0.003 17.7 0.4 8.7 9 0 0 9 9 9 3 PPR repeat PPR_1 PF12854.7 CEP17974.1 - 4.7e-07 29.4 10.6 0.09 12.5 0.0 6.5 7 0 0 7 7 7 3 PPR repeat RPM2 PF08579.11 CEP17974.1 - 0.00021 21.6 3.9 5.2 7.5 0.1 4.0 3 1 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 CEP17974.1 - 0.045 12.9 0.5 21 4.1 0.0 4.3 3 2 1 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway Hfq PF17209.3 CEP17974.1 - 0.053 13.2 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Hfq protein STE PF02200.16 CEP17975.1 - 3.3e-55 185.2 0.1 5.9e-55 184.4 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 CEP17975.1 - 1.9e-10 40.6 10.4 4.6e-05 23.6 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP17975.1 - 4.3e-08 33.3 9.1 0.00065 20.3 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP17975.1 - 7.6e-07 29.3 2.5 7.6e-07 29.3 2.5 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEP17975.1 - 0.00012 22.0 1.3 0.00012 22.0 1.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger SUIM_assoc PF16619.5 CEP17975.1 - 0.00024 21.1 26.5 0.0032 17.5 1.4 5.1 5 0 0 5 5 5 3 Unstructured region C-term to UIM in Ataxin3 Pox_Ag35 PF03286.14 CEP17975.1 - 0.0038 17.0 6.6 0.0038 17.0 6.6 2.5 3 0 0 3 3 3 1 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 CEP17975.1 - 0.0062 17.2 11.7 0.0062 17.2 11.7 3.1 3 0 0 3 3 3 1 Protein of unknown function (FYDLN_acid) DUF4834 PF16118.5 CEP17975.1 - 0.009 16.9 4.7 0.009 16.9 4.7 4.4 4 1 0 4 4 3 1 Domain of unknown function (DUF4834) RNA_pol_3_Rpc31 PF11705.8 CEP17975.1 - 0.013 15.8 5.9 0.013 15.8 5.9 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2_jaz PF12171.8 CEP17975.1 - 0.016 15.5 0.5 0.016 15.5 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP17975.1 - 0.027 14.9 5.6 0.11 12.9 0.9 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PBP1_TM PF14812.6 CEP17975.1 - 1.4 9.3 17.4 2.3 8.7 12.1 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fasciclin PF02469.22 CEP17976.1 - 6e-16 58.8 0.4 7.6e-16 58.5 0.4 1.1 1 0 0 1 1 1 1 Fasciclin domain SWIB PF02201.18 CEP17977.1 - 2.4e-28 97.8 0.2 2.4e-28 97.8 0.2 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain Vps51 PF08700.11 CEP17978.1 - 0.043 13.9 0.6 0.083 13.0 0.6 1.4 1 0 0 1 1 1 0 Vps51/Vps67 p450 PF00067.22 CEP17979.1 - 2.1e-76 257.5 0.0 2.7e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.29 CEP17979.1 - 8.9e-22 77.8 0.1 1.8e-21 76.8 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP17979.1 - 1.7e-09 37.8 0.1 2.7e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Chitin_synth_2 PF03142.15 CEP17980.1 - 4.6e-238 791.1 2.2 7.4e-238 790.4 2.2 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP17980.1 - 6.2e-148 494.0 4.2 1.1e-147 493.2 4.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 CEP17980.1 - 1.9e-18 66.4 0.2 7.2e-14 51.7 0.0 3.9 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 CEP17980.1 - 3.4e-14 53.3 0.0 6.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP17980.1 - 3.6e-13 49.9 3.1 3.6e-13 49.9 3.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP17980.1 - 4.9e-05 23.2 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP17980.1 - 0.00058 19.4 0.0 0.0056 16.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 CEP17980.1 - 0.0074 16.6 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP17980.1 - 0.011 16.2 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain WBS_methylT PF12589.8 CEP17981.1 - 4e-22 78.8 7.5 6.1e-22 78.2 7.5 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CEP17981.1 - 2.4e-11 44.1 0.0 3.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP17981.1 - 1.4e-09 38.5 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP17981.1 - 5.2e-06 27.1 0.0 1.1e-05 26.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP17981.1 - 9.2e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP17981.1 - 0.00041 20.2 0.0 0.00063 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 CEP17981.1 - 0.0063 16.8 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.19 CEP17981.1 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CEP17981.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CEP17981.1 - 0.047 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S13 PF00416.22 CEP17982.1 - 1.6e-19 70.6 0.5 1.1e-17 64.6 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEP17982.1 - 0.023 13.5 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DEAD PF00270.29 CEP17983.1 - 3.2e-45 154.1 0.7 1.1e-44 152.3 0.7 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP17983.1 - 5.4e-33 113.6 1.0 2.9e-31 108.1 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP17983.1 - 5.6e-08 33.0 0.1 5.6e-08 33.0 0.1 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP17983.1 - 0.0042 17.4 0.1 0.016 15.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain Chitin_synth_2 PF03142.15 CEP17984.1 - 7.9e-80 269.0 4.2 5.4e-61 206.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP17984.1 - 1.3e-05 25.3 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEP17984.1 - 0.00031 20.6 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 DEK_C PF08766.11 CEP17984.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain Glyco_transf_21 PF13506.6 CEP17984.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF4014 PF13198.6 CEP17984.1 - 0.12 12.8 1.6 0.47 10.9 1.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) CENP-B_dimeris PF09026.10 CEP17984.1 - 5.1 7.6 11.2 19 5.7 11.2 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cyclin PF08613.11 CEP17985.1 - 1.5e-10 41.7 0.2 3.5e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP17985.1 - 0.003 17.3 0.5 0.037 13.8 0.5 2.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain LUC7 PF03194.15 CEP17986.1 - 6.4e-72 242.2 16.8 6.4e-72 242.2 16.8 1.4 1 1 0 1 1 1 1 LUC7 N_terminus Ran-binding PF05508.11 CEP17986.1 - 0.23 10.4 4.1 0.38 9.7 0.5 2.2 2 0 0 2 2 2 0 RanGTP-binding protein CSN5_C PF18323.1 CEP17986.1 - 0.81 10.6 9.0 1.5 9.8 3.3 3.2 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain V_ATPase_I PF01496.19 CEP17986.1 - 2.2 6.1 11.5 6.5 4.5 10.4 2.1 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family GPI-anchored PF10342.9 CEP17987.1 - 5.5e-09 36.7 0.7 1.1e-08 35.7 0.7 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Phage_TAC_12 PF12363.8 CEP17987.1 - 0.23 11.9 0.0 0.45 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Glyco_hydro_35 PF01301.19 CEP17988.1 - 1.8e-62 211.8 4.5 2.5e-60 204.7 4.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CEP17988.1 - 3.5e-12 46.9 0.3 1.3e-05 25.7 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 CEP17988.1 - 2.1e-06 27.4 0.1 4.4e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 CEP17988.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RasGEF PF00617.19 CEP17989.1 - 5.6e-41 140.7 0.4 1.1e-40 139.7 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain Zn_clus PF00172.18 CEP17991.1 - 1.8e-10 40.7 24.6 9.4e-06 25.7 8.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP-utilisers_N PF05524.13 CEP17991.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TACC_C PF05010.14 CEP17991.1 - 0.16 11.7 0.4 0.39 10.5 0.4 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal F-box-like PF12937.7 CEP17992.1 - 2.4e-06 27.4 1.4 4.9e-06 26.3 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP17992.1 - 2.2e-05 24.2 0.3 5.2e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CEP17992.1 - 0.0065 16.3 2.3 0.0099 15.8 0.0 2.4 3 0 0 3 3 3 1 F-box AdoMet_MTase PF07757.13 CEP17992.1 - 0.1 13.0 0.1 0.32 11.3 0.2 1.7 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Ank_2 PF12796.7 CEP17993.1 - 8.5e-61 202.5 13.4 9.5e-19 67.8 1.4 6.6 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP17993.1 - 1.9e-54 181.4 6.5 4.2e-12 46.3 0.1 6.9 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP17993.1 - 7.1e-53 170.4 7.0 6.7e-07 29.1 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 CEP17993.1 - 3.8e-48 159.9 18.0 1.6e-06 28.3 0.1 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 CEP17993.1 - 1.7e-42 142.9 11.5 3e-07 30.6 0.3 8.5 3 3 6 9 9 9 9 Ankyrin repeats (many copies) ARTD15_N PF18084.1 CEP17993.1 - 0.13 12.6 0.1 0.52 10.6 0.1 2.1 1 0 0 1 1 1 0 ARTD15 N-terminal domain NAD_binding_1 PF00175.21 CEP17994.1 - 1.7e-29 102.6 0.0 3.8e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CEP17994.1 - 9.7e-26 90.0 0.0 1.4e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CEP17994.1 - 2.7e-08 34.1 0.0 2.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CEP17994.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Velvet PF11754.8 CEP17995.1 - 1.1e-47 163.1 2.9 2e-31 109.8 0.3 4.0 1 1 2 3 3 3 2 Velvet factor SBP_bac_5 PF00496.22 CEP17995.1 - 0.075 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle PBP1_TM PF14812.6 CEP17995.1 - 0.1 13.0 3.6 0.24 11.8 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 CEP17995.1 - 6.9 4.8 6.8 9.6 4.4 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SRF-TF PF00319.18 CEP17996.1 - 2.7e-21 74.8 0.1 4.6e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIA PF03153.13 CEP17996.1 - 5.7 6.8 37.3 8.8 6.2 37.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH3_9 PF14604.6 CEP17997.1 - 1.1e-35 121.3 1.1 9.8e-15 54.2 0.1 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CEP17997.1 - 2e-35 120.1 3.7 1.2e-12 47.2 0.1 3.7 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 CEP17997.1 - 1e-31 108.3 0.3 5.8e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Nup54_57_C PF18570.1 CEP17997.1 - 0.24 11.0 3.7 17 5.1 0.2 3.4 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain tRNA-synt_2b PF00587.25 CEP17998.1 - 1.1e-42 146.1 0.0 1.8e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CEP17998.1 - 6.9e-17 61.4 0.1 1.4e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain RseA_C PF03873.13 CEP17998.1 - 0.2 11.9 1.2 0.55 10.5 1.2 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Ank_2 PF12796.7 CEP17999.1 - 1e-90 298.4 46.7 2e-12 47.5 0.0 18.8 10 5 9 19 19 19 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP17999.1 - 3e-78 257.2 49.1 1.6e-10 41.3 0.1 23.2 19 5 7 26 26 26 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP17999.1 - 9e-56 185.2 32.6 1.1e-05 25.6 0.0 19.4 12 4 8 20 20 20 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP17999.1 - 3.6e-52 168.2 48.8 0.00055 20.2 0.1 27.3 30 0 0 30 30 30 10 Ankyrin repeat Ank PF00023.30 CEP17999.1 - 2.3e-47 157.4 40.9 0.028 14.9 0.0 23.5 24 1 0 24 24 24 12 Ankyrin repeat PARP PF00644.20 CEP17999.1 - 1.7e-41 142.0 0.0 4.3e-41 140.7 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 CEP17999.1 - 1.5e-15 57.0 1.0 3.4e-15 55.8 0.1 2.1 2 0 0 2 2 2 1 WGR domain PARP_reg PF02877.14 CEP17999.1 - 2.7e-14 53.4 1.8 2.6e-13 50.3 0.1 2.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain zf-CRD PF17979.1 CEP17999.1 - 0.00069 19.8 0.3 0.00069 19.8 0.3 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-CCHH PF10283.9 CEP17999.1 - 0.00071 19.5 0.8 0.002 18.1 0.8 1.8 1 0 0 1 1 1 1 PBZ domain Bax1-I PF01027.20 CEP18000.1 - 1.6e-18 67.3 15.1 1.6e-18 67.3 15.1 1.9 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Ribosomal_S7 PF00177.21 CEP18001.1 - 3.2e-37 127.5 0.8 3.9e-37 127.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e His_Phos_2 PF00328.22 CEP18002.1 - 2.8e-90 303.5 0.4 3.5e-90 303.1 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CEP18002.1 - 2.7e-38 130.0 0.0 6.2e-38 128.8 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CEP18002.1 - 2.9e-07 30.3 0.0 5.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain SET PF00856.28 CEP18003.1 - 7.1e-10 39.5 2.8 5.5e-09 36.6 0.0 3.3 2 2 0 2 2 2 1 SET domain PHD PF00628.29 CEP18003.1 - 1.2e-08 34.7 10.3 2.5e-08 33.7 10.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CEP18003.1 - 0.35 10.5 6.4 0.63 9.7 6.4 1.4 1 0 0 1 1 1 0 PHD-finger DUF3006 PF11213.8 CEP18003.1 - 1.4 9.2 4.6 20 5.5 2.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3006) CheX PF13690.6 CEP18003.1 - 2 8.6 3.6 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX Acyl-CoA_dh_1 PF00441.24 CEP18004.1 - 3.7e-29 101.9 0.6 5.8e-29 101.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CEP18004.1 - 1.4e-26 93.4 0.0 3.1e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CEP18004.1 - 2.9e-20 72.3 0.0 4.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CEP18004.1 - 2.2e-08 34.5 0.5 5e-08 33.3 0.5 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 CEP18005.1 - 1.3e-20 73.8 0.0 4.5e-20 72.1 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CEP18005.1 - 0.00028 19.8 0.0 0.00028 19.8 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CEP18005.1 - 0.00079 18.8 0.0 0.0077 15.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rit1_C PF17184.4 CEP18006.1 - 8.3e-97 323.9 0.0 1.1e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CEP18006.1 - 2.3e-12 47.2 0.0 4.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 CEP18006.1 - 8.8e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Med31 PF05669.12 CEP18008.1 - 3.2e-36 123.2 13.2 3.8e-36 123.0 13.2 1.1 1 0 0 1 1 1 1 SOH1 HAD_2 PF13419.6 CEP18008.1 - 0.028 14.5 0.1 0.032 14.3 0.1 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ULD PF16534.5 CEP18008.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like oligomerisation domain of SATB DUF2347 PF09804.9 CEP18010.1 - 1.7e-69 234.6 0.4 2.8e-69 233.8 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 CEP18010.1 - 1.1e-09 38.6 1.1 3.6e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.10 CEP18010.1 - 2.3e-09 37.2 0.2 5.6e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CEP18010.1 - 1.8e-07 30.2 2.0 3.3e-05 22.8 1.2 3.0 1 1 1 2 2 2 1 Transport protein Avl9 Afi1 PF07792.12 CEP18010.1 - 0.0063 17.0 0.6 0.043 14.3 0.0 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2373 PF10180.9 CEP18010.1 - 0.0089 15.9 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Sas10_Utp3 PF04000.15 CEP18010.1 - 0.021 15.4 0.1 0.051 14.2 0.1 1.6 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Hist_deacetyl PF00850.19 CEP18011.1 - 8.2e-23 81.3 0.0 1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NAD_kinase PF01513.21 CEP18012.1 - 2.1e-62 211.0 0.0 4.5e-61 206.6 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase CDC27 PF09507.10 CEP18012.1 - 6.6e-35 121.3 47.9 2.5e-34 119.4 42.4 2.8 2 1 0 2 2 2 1 DNA polymerase subunit Cdc27 HTH_15 PF12324.8 CEP18012.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Fmp27 PF10344.9 CEP18013.1 - 0.17 10.0 1.9 0.15 10.1 1.9 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Mucin PF01456.17 CEP18013.1 - 0.31 11.0 21.3 0.42 10.6 21.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.25 CEP18014.1 - 7.7e-39 133.2 0.0 4.2e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Fapy_DNA_glyco PF01149.24 CEP18014.1 - 3.9e-24 85.5 0.0 1.1e-23 84.0 0.0 1.9 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain adh_short_C2 PF13561.6 CEP18014.1 - 7.8e-23 81.3 0.0 8.6e-20 71.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase H2TH PF06831.14 CEP18014.1 - 9.5e-20 70.4 0.0 3.1e-19 68.8 0.0 2.0 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain HLH PF00010.26 CEP18014.1 - 2.4e-14 53.0 2.9 4.1e-14 52.3 1.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KR PF08659.10 CEP18014.1 - 3.6e-08 33.5 0.1 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 KR domain Pyr_redox_2 PF07992.14 CEP18014.1 - 0.00033 20.0 0.1 0.00067 19.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_34 PF11312.8 CEP18015.1 - 4.5e-46 157.5 1.0 1.2e-45 156.1 1.0 1.6 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase CheR PF01739.18 CEP18015.1 - 0.00016 21.2 2.2 0.57 9.6 0.7 3.1 2 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain RE_LlaMI PF09562.10 CEP18015.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 LlaMI restriction endonuclease Med2 PF11214.8 CEP18015.1 - 0.14 12.4 1.3 2.6 8.3 0.5 2.3 1 1 1 2 2 2 0 Mediator complex subunit 2 Mpv17_PMP22 PF04117.12 CEP18016.1 - 4.7e-08 33.1 1.6 9.2e-08 32.2 1.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family EB PF01683.18 CEP18017.1 - 0.0031 17.8 4.9 0.0083 16.4 4.9 1.6 1 1 0 1 1 1 1 EB module Dickkopf_N PF04706.12 CEP18017.1 - 0.031 14.8 7.9 0.05 14.1 7.9 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Lipase_3 PF01764.25 CEP18018.1 - 1e-16 61.1 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) RNA_pol_3_Rpc31 PF11705.8 CEP18018.1 - 0.00027 21.3 7.9 0.00062 20.1 7.9 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Abhydrolase_6 PF12697.7 CEP18018.1 - 0.00095 19.8 0.4 0.0026 18.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CEP18018.1 - 0.0039 16.9 0.1 0.0091 15.7 0.1 1.6 1 0 0 1 1 1 1 PGAP1-like protein SDA1 PF05285.12 CEP18018.1 - 0.0043 16.5 8.6 0.0063 16.0 8.6 1.3 1 0 0 1 1 1 1 SDA1 CDC27 PF09507.10 CEP18018.1 - 0.013 14.9 8.2 0.02 14.3 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 CEP18018.1 - 0.018 14.4 8.1 0.026 13.9 8.1 1.2 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 CEP18018.1 - 0.027 13.5 11.5 0.042 12.9 11.5 1.3 1 0 0 1 1 1 0 Paf1 Hydrolase_4 PF12146.8 CEP18018.1 - 0.16 11.2 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pox_Ag35 PF03286.14 CEP18018.1 - 0.25 11.1 7.6 0.46 10.2 7.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 CEP18018.1 - 0.4 10.2 15.7 0.75 9.3 15.7 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 CEP18018.1 - 0.64 9.7 13.7 1.1 8.9 13.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 CEP18018.1 - 0.67 9.1 10.5 1.3 8.1 10.5 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RPN2_C PF18004.1 CEP18018.1 - 0.91 9.4 7.0 0.77 9.7 5.4 1.7 2 0 0 2 2 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TFB6 PF17110.5 CEP18018.1 - 1.2 8.9 5.3 2.2 8.0 5.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Roughex PF06020.11 CEP18018.1 - 6.6 5.7 10.2 12 4.9 10.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 CEP18018.1 - 7.5 6.2 12.5 18 5.0 12.5 1.6 1 0 0 1 1 1 0 FAM176 family GLTP PF08718.11 CEP18019.1 - 4.1e-46 157.0 1.7 4.9e-46 156.7 0.1 2.0 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Myb_DNA-binding PF00249.31 CEP18021.1 - 0.0042 17.2 0.0 0.0097 16.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP18021.1 - 0.0059 16.8 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain FMN_dh PF01070.18 CEP18022.1 - 1.6e-114 382.6 0.1 2.6e-103 345.7 0.0 2.5 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Forkhead PF00250.18 CEP18022.1 - 8.8e-38 128.4 0.1 2.6e-37 127.0 0.1 1.9 1 0 0 1 1 1 1 Forkhead domain Cyt-b5 PF00173.28 CEP18022.1 - 7.2e-25 86.9 0.0 1.5e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.26 CEP18022.1 - 4.7e-12 46.1 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Glu_synthase PF01645.17 CEP18022.1 - 4.2e-09 36.0 0.0 9.2e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CEP18022.1 - 0.00064 18.8 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CEP18022.1 - 0.0067 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase FHA_2 PF17913.1 CEP18022.1 - 0.024 14.8 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 FHA domain Linker_histone PF00538.19 CEP18022.1 - 0.091 13.1 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 linker histone H1 and H5 family NIF PF03031.18 CEP18023.1 - 2.5e-35 121.6 0.5 5.7e-35 120.4 0.5 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 CEP18023.1 - 0.1 11.3 6.2 0.14 10.8 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 CEP18023.1 - 2.7 6.0 10.7 3.5 5.6 10.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EPL1 PF10513.9 CEP18023.1 - 4.2 7.7 16.4 1.9 8.9 1.3 2.7 2 1 0 2 2 2 0 Enhancer of polycomb-like PHD PF00628.29 CEP18024.1 - 3.9e-07 29.9 2.7 1e-06 28.5 2.7 1.7 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 CEP18024.1 - 0.0082 16.6 0.3 0.0082 16.6 0.3 3.3 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_Oberon PF07227.11 CEP18024.1 - 0.018 15.0 0.5 0.036 13.9 0.5 1.4 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 CEP18024.1 - 0.081 12.9 0.3 0.081 12.9 0.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CEP18024.1 - 0.14 11.7 1.6 0.35 10.5 1.6 1.7 1 0 0 1 1 1 0 PHD-finger WHIM1 PF15612.6 CEP18024.1 - 0.15 11.7 0.2 0.35 10.5 0.2 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 zinc_ribbon_10 PF10058.9 CEP18024.1 - 0.39 10.5 2.1 0.42 10.4 0.2 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Abhydrolase_3 PF07859.13 CEP18025.1 - 3.7e-25 89.0 0.0 5.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP18025.1 - 3.9e-17 62.2 0.1 6.1e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEP18025.1 - 6.2e-05 22.6 0.1 0.0064 16.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Kinase-PPPase PF03618.14 CEP18025.1 - 0.051 13.4 0.2 2 8.1 0.0 2.4 2 1 0 2 2 2 0 Kinase/pyrophosphorylase FAR1 PF03101.15 CEP18026.1 - 1.9e-05 25.3 1.3 2.8e-05 24.7 1.3 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Methyltransf_10 PF05971.12 CEP18027.1 - 2.1e-79 267.0 0.0 3.4e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 CEP18027.1 - 1.7e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Dishevelled PF02377.15 CEP18027.1 - 0.057 13.9 2.7 0.098 13.1 2.7 1.3 1 0 0 1 1 1 0 Dishevelled specific domain Methyltransf_4 PF02390.17 CEP18027.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase TPR_19 PF14559.6 CEP18028.1 - 2.4e-11 44.0 0.3 5.8e-06 26.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP18028.1 - 1.3e-08 35.0 4.5 0.0033 17.7 0.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CEP18028.1 - 3.2e-08 33.7 1.5 0.24 12.1 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18028.1 - 7.4e-08 31.9 0.0 0.89 9.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP18028.1 - 4.2e-07 30.1 0.7 0.005 17.0 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CEP18028.1 - 3.7e-06 27.3 0.3 0.27 12.2 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP18028.1 - 3.9e-05 23.9 0.1 0.38 11.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP18028.1 - 4.1e-05 23.2 0.3 0.71 9.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CEP18028.1 - 0.00016 21.4 1.6 0.55 10.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP18028.1 - 0.0003 20.8 0.8 0.089 13.1 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP18028.1 - 0.0012 18.3 0.8 0.0021 17.5 0.8 1.6 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 CEP18028.1 - 0.0013 18.6 1.3 0.42 10.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 CEP18028.1 - 0.0021 17.8 1.7 0.0069 16.1 1.7 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 CEP18028.1 - 0.0038 17.4 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP18028.1 - 0.013 15.8 4.7 1.1 9.8 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 CEP18028.1 - 0.014 15.6 0.8 0.79 10.1 0.1 3.5 4 0 0 4 4 3 0 PPR repeat Type_III_YscG PF09477.10 CEP18028.1 - 0.093 12.8 0.3 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) FMN_red PF03358.15 CEP18029.1 - 1.8e-12 47.2 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEP18029.1 - 2.9e-05 23.9 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CEP18029.1 - 0.08 13.1 0.1 0.42 10.8 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin FMN_red PF03358.15 CEP18030.1 - 7.9e-13 48.4 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CEP18030.1 - 1.9e-06 27.7 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CEP18030.1 - 0.0039 17.4 0.1 0.46 10.7 0.0 2.8 1 1 1 2 2 2 1 Flavodoxin bZIP_2 PF07716.15 CEP18031.1 - 6e-11 42.2 13.1 6e-11 42.2 13.1 2.3 2 1 1 3 3 3 2 Basic region leucine zipper Phlebovirus_NSM PF07246.11 CEP18031.1 - 0.097 12.0 7.3 0.075 12.4 5.8 1.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M SMYLE_N PF18615.1 CEP18031.1 - 0.33 10.5 9.5 0.4 10.2 9.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain bZIP_1 PF00170.21 CEP18031.1 - 0.95 9.6 14.6 0.1 12.7 9.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor LMBR1 PF04791.16 CEP18031.1 - 6.1 5.6 6.8 7.3 5.4 6.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Vfa1 PF08432.10 CEP18031.1 - 6.2 7.1 13.5 6.8 7.0 0.4 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Phi_1 PF04674.12 CEP18032.1 - 0.46 9.8 2.2 0.82 8.9 2.2 1.5 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region peroxidase PF00141.23 CEP18033.1 - 1.4e-39 136.2 0.0 3.3e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 Peroxidase DUF3808 PF10300.9 CEP18036.1 - 5.3e-95 318.9 12.3 8.1e-48 163.3 3.7 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CEP18036.1 - 1.8e-07 30.7 4.5 0.57 10.4 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP18036.1 - 0.078 12.8 10.3 4.7 7.2 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP18036.1 - 0.19 11.1 5.7 9.7 5.4 0.7 3.4 3 2 0 3 3 3 0 MalT-like TPR region TPR_11 PF13414.6 CEP18036.1 - 0.38 10.5 6.8 0.8 9.4 0.3 3.9 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 CEP18036.1 - 1.1 9.6 8.8 1.5 9.2 0.9 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat PGK PF00162.19 CEP18037.1 - 2.5e-154 513.8 2.1 2.8e-154 513.6 2.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 CEP18037.1 - 0.041 13.9 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 PA domain PrpR_N PF06506.11 CEP18037.1 - 0.12 12.0 0.3 0.83 9.2 0.0 2.4 2 1 0 2 2 2 0 Propionate catabolism activator MMR_HSR1_Xtn PF16897.5 CEP18038.1 - 6.9e-42 141.8 2.5 3.1e-41 139.7 1.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CEP18038.1 - 7.7e-24 83.5 0.1 1.4e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CEP18038.1 - 2.2e-21 76.1 0.0 4.6e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP18038.1 - 2.8e-11 43.2 0.1 1.2e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CEP18038.1 - 0.0039 16.2 2.0 0.0083 15.1 0.4 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CEP18038.1 - 0.0082 16.2 0.4 2 8.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 CEP18038.1 - 0.011 15.3 0.2 13 5.2 0.0 3.4 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP18038.1 - 0.27 11.1 1.7 8.3 6.3 0.1 2.9 2 1 1 3 3 3 0 RsgA GTPase SQHop_cyclase_C PF13243.6 CEP18039.1 - 2.2e-49 168.3 0.1 6.5e-45 153.6 0.1 2.6 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CEP18039.1 - 9.4e-44 149.7 0.6 1.8e-38 132.3 0.0 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CEP18039.1 - 2.3e-25 88.0 4.9 8.4e-07 28.6 0.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CEP18039.1 - 2.4e-05 23.5 0.2 8.1e-05 21.8 0.2 1.9 1 1 0 1 1 1 1 A-macroglobulin TED domain Pec_lyase PF09492.10 CEP18039.1 - 0.0016 17.8 5.4 1.6 8.0 0.0 4.2 3 1 2 5 5 5 2 Pectic acid lyase ALS_ss_C PF10369.9 CEP18040.1 - 5.2e-19 68.2 0.4 3.5e-17 62.4 0.0 2.6 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 CEP18040.1 - 1.8e-12 46.8 0.1 3.1e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CEP18040.1 - 4.5e-07 29.6 0.0 9.5e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF3337 PF11816.8 CEP18040.1 - 0.061 13.2 0.3 0.48 10.3 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3337) Macro PF01661.21 CEP18041.1 - 6.5e-34 116.5 0.1 9.9e-34 115.9 0.1 1.3 1 0 0 1 1 1 1 Macro domain AMP-binding PF00501.28 CEP18042.1 - 2.2e-45 155.0 0.1 9.5e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CEP18042.1 - 4.2e-35 121.2 0.0 4.4e-34 117.8 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 CEP18042.1 - 7.2e-08 32.7 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CEP18042.1 - 0.00042 19.9 0.0 0.0031 17.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phos_pyr_kin PF08543.12 CEP18043.1 - 1.6e-14 53.9 0.2 3.9e-14 52.6 0.2 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CEP18043.1 - 1.2e-08 34.7 0.1 1.5e-07 31.1 0.0 2.3 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Glutaredoxin PF00462.24 CEP18044.1 - 5e-14 52.2 0.0 1.4e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Arrestin_C PF02752.22 CEP18044.1 - 5.4e-12 46.3 0.9 1.1e-07 32.4 0.2 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP18044.1 - 3.6e-08 33.6 0.0 8.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF836 PF05768.14 CEP18044.1 - 0.016 15.6 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 CEP18044.1 - 0.021 15.2 0.0 0.064 13.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WD-3 PF09765.9 CEP18045.1 - 1.1e-35 123.3 1.9 9.2e-27 94.1 0.3 2.0 1 1 1 2 2 2 2 WD-repeat region Auxin_resp PF06507.13 CEP18045.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Auxin response factor Ras PF00071.22 CEP18046.1 - 2.5e-46 157.2 0.0 4.6e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18046.1 - 8.6e-17 61.5 0.0 2.2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Myb_DNA-binding PF00249.31 CEP18046.1 - 2.4e-05 24.4 0.0 7.5e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP18046.1 - 0.0084 16.3 1.7 0.035 14.4 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Alpha-2-MRAP_C PF06401.11 CEP18046.1 - 0.98 9.3 8.9 3.9 7.4 4.9 3.2 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain LapA_dom PF06305.11 CEP18046.1 - 1.4 8.8 3.3 2.8 7.8 0.4 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HSP9_HSP12 PF04119.12 CEP18047.1 - 0.0045 17.3 0.2 0.0075 16.6 0.2 1.4 1 1 0 1 1 1 1 Heat shock protein 9/12 RasGEF PF00617.19 CEP18049.1 - 3e-31 109.0 1.7 3e-30 105.7 1.7 2.5 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP18049.1 - 2.2e-13 50.3 1.2 2.2e-13 50.3 1.2 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif Syntaxin-18_N PF10496.9 CEP18049.1 - 0.18 12.1 4.0 0.33 11.2 0.4 3.0 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus zf-HC5HC2H_2 PF13832.6 CEP18050.1 - 1e-14 54.6 6.8 1e-14 54.6 6.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 CEP18050.1 - 3e-12 45.9 1.6 3e-12 45.9 1.6 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 CEP18050.1 - 2.3e-10 40.6 5.9 2.3e-10 40.6 5.9 3.2 1 1 2 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.29 CEP18050.1 - 1.7e-08 34.2 17.6 1.7e-08 34.2 6.7 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.11 CEP18050.1 - 0.017 15.4 8.7 0.017 15.4 8.7 3.3 3 1 1 4 4 4 0 RING-like domain DNA_pol_phi PF04931.13 CEP18050.1 - 7.3 4.6 40.9 15 3.6 40.9 1.5 1 0 0 1 1 1 0 DNA polymerase phi PDZ_5 PF17817.1 CEP18051.1 - 0.028 14.7 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Vma12 PF11712.8 CEP18052.1 - 2e-19 70.0 0.4 2.8e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase FISNA PF14484.6 CEP18053.1 - 0.034 14.4 0.1 4.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Fish-specific NACHT associated domain DegT_DnrJ_EryC1 PF01041.17 CEP18054.1 - 0.023 14.0 3.4 0.026 13.8 0.1 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4588 PF15251.6 CEP18054.1 - 0.13 12.0 13.7 1.9 8.2 13.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Arginase PF00491.21 CEP18055.1 - 1e-87 294.2 0.0 1.2e-87 294.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CEP18055.1 - 0.0024 18.1 0.1 0.0044 17.3 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Tox-REase-9 PF15650.6 CEP18055.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 Sel1 PF08238.12 CEP18056.1 - 3.9e-34 116.3 24.2 2.6e-08 34.3 0.0 11.6 11 0 0 11 11 11 8 Sel1 repeat TPR_6 PF13174.6 CEP18056.1 - 0.0015 19.0 7.3 17 6.3 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP18056.1 - 0.0019 18.1 3.4 1.2 9.3 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Herpes_TK PF00693.18 CEP18056.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus TPR_14 PF13428.6 CEP18056.1 - 0.31 12.0 9.5 39 5.4 0.6 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat IreB PF06135.12 CEP18056.1 - 0.31 11.3 1.8 10 6.4 0.1 3.2 3 0 0 3 3 3 0 IreB regulatory phosphoprotein ATP-synt_ab PF00006.25 CEP18057.1 - 1.1e-63 214.7 0.0 2.2e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEP18057.1 - 5.8e-17 62.0 6.4 1.1e-16 61.0 3.4 3.0 3 1 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 CEP18057.1 - 0.0094 15.2 0.7 0.016 14.4 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 CEP18057.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CEP18057.1 - 0.016 15.6 0.1 0.059 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CEP18057.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CEP18057.1 - 0.034 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T3SS_ATPase_C PF18269.1 CEP18057.1 - 0.038 13.9 0.8 0.23 11.3 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 CEP18057.1 - 0.039 13.3 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA PF00004.29 CEP18057.1 - 0.053 13.9 0.0 0.6 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CEP18057.1 - 0.066 13.5 0.8 0.31 11.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP18057.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AMPK1_CBM PF16561.5 CEP18060.1 - 7.2e-14 51.8 0.3 1.5e-13 50.7 0.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 CEP18060.1 - 0.002 18.5 0.1 0.0041 17.5 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF4431 PF14485.6 CEP18060.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Rhodanese PF00581.20 CEP18062.1 - 6e-11 42.8 0.0 9.4e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain DUF4881 PF16222.5 CEP18062.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) FH2 PF02181.23 CEP18063.1 - 9.9e-85 284.9 4.7 9.9e-85 284.9 4.7 2.7 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CEP18063.1 - 1e-25 90.4 14.3 1.3e-20 73.8 0.2 4.7 4 0 0 4 4 4 3 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEP18063.1 - 5.8e-06 26.1 1.0 5.8e-06 26.1 1.0 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Ras PF00071.22 CEP18064.1 - 1.2e-32 112.8 1.8 2.2e-19 69.6 0.2 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CEP18064.1 - 1.4e-19 70.4 1.6 1.5e-17 63.9 0.2 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CEP18064.1 - 7e-06 26.1 0.1 9.5e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP18064.1 - 8e-06 25.4 0.9 8e-05 22.1 0.1 2.0 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CEP18064.1 - 8.2e-06 25.4 0.9 0.00076 19.0 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CEP18064.1 - 0.0018 17.7 0.7 0.036 13.5 0.1 2.1 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEP18064.1 - 0.0025 18.2 0.0 0.0039 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CEP18064.1 - 0.0089 15.9 2.4 0.54 10.2 0.5 2.9 1 1 2 3 3 3 1 RsgA GTPase Septin PF00735.18 CEP18064.1 - 0.035 13.4 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CEP18064.1 - 0.05 13.1 0.1 0.093 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CEP18064.1 - 0.092 12.5 0.2 0.19 11.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP18064.1 - 0.11 13.1 0.3 0.18 12.3 0.3 1.5 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CEP18064.1 - 0.16 12.3 0.1 0.9 9.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain Fasciclin PF02469.22 CEP18066.1 - 1.4e-16 60.9 9.9 1.9e-11 44.3 1.1 2.7 2 1 0 2 2 2 2 Fasciclin domain Glyoxal_oxid_N PF07250.11 CEP18067.1 - 2.6e-59 200.3 0.0 6.2e-58 195.8 0.0 2.5 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CEP18067.1 - 1.4e-22 79.8 0.0 2.5e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 CEP18067.1 - 0.0022 18.2 0.0 4.1 7.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CEP18067.1 - 0.0065 16.5 0.3 8.1 6.5 0.0 3.3 4 0 0 4 4 4 2 Galactose oxidase, central domain MULE PF10551.9 CEP18068.1 - 0.0015 18.9 0.1 0.0098 16.3 0.0 2.3 2 0 0 2 2 2 1 MULE transposase domain RVT_1 PF00078.27 CEP18069.1 - 4.8e-24 85.1 0.0 7.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.27 CEP18072.1 - 2e-35 122.1 0.0 9.9e-35 119.8 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEP18072.1 - 8.6e-18 64.4 0.0 3.1e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CEP18072.1 - 9e-14 51.6 6.4 1.6e-09 38.0 0.0 4.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CEP18072.1 - 1.4e-10 40.9 0.1 4.7e-10 39.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CEP18072.1 - 1.7e-06 28.1 0.1 1.4e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CEP18072.1 - 0.00027 21.1 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CEP18072.1 - 0.0065 16.3 0.0 0.043 13.6 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CEP18072.1 - 0.076 13.3 0.2 3.3 8.0 0.2 3.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CEP18073.1 - 4.1e-25 88.7 2.8 7.9e-25 87.8 0.1 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CEP18073.1 - 2.5e-14 53.5 1.1 3.4e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 CEP18073.1 - 4.9e-14 52.6 2.7 1.6e-13 50.9 0.2 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CEP18073.1 - 2.2e-13 50.4 1.3 3.8e-13 49.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CEP18073.1 - 5.2e-06 25.9 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CEP18073.1 - 0.0002 21.6 0.1 0.0016 18.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain HCNGP PF07818.13 CEP18073.1 - 0.0056 17.3 0.2 0.014 16.0 0.2 1.7 1 0 0 1 1 1 1 HCNGP-like protein SNF2_N PF00176.23 CEP18073.1 - 0.0084 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain T2SSE PF00437.20 CEP18073.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CEP18073.1 - 0.041 13.7 1.3 0.65 9.7 0.7 2.4 1 1 1 2 2 2 0 AAA domain DDE_3 PF13358.6 CEP18074.1 - 1.6e-24 86.3 0.0 3.8e-16 59.2 0.0 2.8 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_29 PF13551.6 CEP18074.1 - 0.00092 19.2 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 CEP18074.1 - 0.0015 18.4 0.1 0.0039 17.1 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 CEP18074.1 - 0.0024 17.6 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP18074.1 - 0.012 16.2 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CEP18074.1 - 0.012 15.7 0.1 0.072 13.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 CEP18074.1 - 0.061 13.5 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP18074.1 - 0.085 13.2 0.3 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Transposase AAA_14 PF13173.6 CEP18074.1 - 0.13 12.2 0.3 0.61 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF1455 PF07306.11 CEP18076.1 - 0.071 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DRMBL PF07522.14 CEP18078.1 - 1.2e-30 106.0 0.0 2.3e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CEP18078.1 - 1.8e-05 24.3 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2054 PF10218.9 CEP18078.1 - 0.044 13.9 0.4 0.13 12.3 0.4 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) DUF3696 PF12476.8 CEP18078.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) HLH PF00010.26 CEP18079.1 - 2.2e-19 69.2 1.6 6.8e-18 64.4 0.0 3.0 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Spore_YhcN_YlaJ PF09580.10 CEP18079.1 - 0.038 14.1 9.0 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Med15 PF09606.10 CEP18079.1 - 0.042 12.5 22.8 0.058 12.1 22.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.6 CEP18079.1 - 0.074 12.4 12.2 0.11 11.9 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alpha-2-MRAP_C PF06401.11 CEP18079.1 - 0.17 11.9 15.8 0.032 14.2 9.7 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF2448 PF10476.9 CEP18079.1 - 0.44 10.4 4.1 9.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DUF5327 PF17261.2 CEP18079.1 - 0.57 11.0 14.5 0.32 11.8 11.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Dishevelled PF02377.15 CEP18079.1 - 0.79 10.2 10.7 1.6 9.2 1.7 2.2 2 0 0 2 2 2 0 Dishevelled specific domain REC114-like PF15165.6 CEP18079.1 - 0.94 9.2 13.8 0.3 10.9 10.9 1.5 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like Spt20 PF12090.8 CEP18079.1 - 1.3 8.6 26.0 0.25 10.9 22.4 1.6 2 0 0 2 2 2 0 Spt20 family CCDC53 PF10152.9 CEP18079.1 - 1.4 9.3 12.9 1.9 8.9 12.2 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex GvpL_GvpF PF06386.11 CEP18079.1 - 1.9 8.4 9.2 8.8 6.2 0.3 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF GAS PF13851.6 CEP18079.1 - 2.2 7.6 23.1 0.026 13.9 15.1 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FAST_2 PF08368.12 CEP18079.1 - 2.3 9.1 9.3 1.7 9.5 6.6 2.0 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Perilipin PF03036.16 CEP18079.1 - 3 6.8 17.3 0.34 9.9 13.0 1.4 2 0 0 2 2 2 0 Perilipin family MAS20 PF02064.15 CEP18079.1 - 3.5 7.7 13.4 0.58 10.3 6.1 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Pex14_N PF04695.13 CEP18079.1 - 4.1 8.1 13.9 0.27 11.9 7.3 2.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 CEP18079.1 - 4.8 5.0 14.1 6.4 4.6 14.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pet20 PF08692.10 CEP18079.1 - 6.7 7.4 10.9 5.7 7.7 7.1 2.2 1 1 0 2 2 2 0 Mitochondrial protein Pet20 DUF4834 PF16118.5 CEP18079.1 - 8.1 7.5 13.4 2.8 8.9 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WD40 PF00400.32 CEP18080.1 - 2.2e-39 132.7 15.8 8.5e-09 35.9 0.1 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat PRP4 PF08799.11 CEP18080.1 - 9e-13 47.5 3.4 9e-13 47.5 3.4 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CEP18080.1 - 2.2e-12 47.1 0.3 2.4e-05 24.5 0.0 4.7 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP18080.1 - 3.7e-05 22.6 0.2 0.0026 16.5 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CEP18080.1 - 0.00098 18.2 0.0 2.1 7.2 0.0 3.5 3 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CEP18080.1 - 0.0011 18.4 0.1 0.46 9.8 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal RNA_pol_Rpb1_5 PF04998.17 CEP18081.1 - 3.4e-93 312.0 0.3 6e-67 225.9 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CEP18081.1 - 6.8e-65 218.3 0.1 1.6e-64 217.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CEP18081.1 - 2.5e-33 115.2 0.0 6.9e-33 113.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CEP18081.1 - 4.9e-27 95.1 1.3 1.1e-25 90.6 0.7 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CEP18081.1 - 2.3e-23 82.2 0.0 1.1e-22 80.0 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 CEP18081.1 - 4.9 6.4 19.1 9.6 5.4 19.1 1.4 1 0 0 1 1 1 0 BUD22 Rotamase PF00639.21 CEP18081.1 - 7.2 7.7 6.1 3.2 8.8 0.0 3.2 2 1 1 3 3 3 0 PPIC-type PPIASE domain Mito_carr PF00153.27 CEP18082.1 - 4.7e-48 161.1 3.2 5.2e-17 61.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MULE PF10551.9 CEP18083.1 - 1.4e-19 70.3 0.1 1.5e-18 67.0 0.1 2.2 2 0 0 2 2 2 1 MULE transposase domain DUF5564 PF17719.1 CEP18083.1 - 0.12 12.5 0.0 0.62 10.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5564) zf-RVT PF13966.6 CEP18084.1 - 1.7e-08 35.1 0.5 4.9e-08 33.6 0.5 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase LSM PF01423.22 CEP18086.1 - 1.1e-15 57.1 0.1 1.4e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF5440 PF17509.2 CEP18086.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5440) RTC PF01137.21 CEP18087.1 - 1.5e-62 210.7 0.0 1.7e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CEP18087.1 - 7e-39 132.5 0.0 1.1e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RNA_pol_L_2 PF13656.6 CEP18088.1 - 3.7e-28 97.1 0.0 1.2e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CEP18088.1 - 1.4e-08 34.0 0.0 2.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3730 PF12530.8 CEP18089.1 - 3.2e-07 30.1 2.3 4.3e-07 29.7 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) F-box-like PF12937.7 CEP18091.1 - 1.4e-08 34.5 0.0 5.4e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP18091.1 - 1.9e-05 24.4 0.9 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 F-box domain DEAD PF00270.29 CEP18092.1 - 8.7e-22 77.7 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP18092.1 - 2.9e-11 43.7 0.0 7.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CEP18092.1 - 0.00049 19.5 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CEP18092.1 - 0.00052 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit bZIP_2 PF07716.15 CEP18093.1 - 4.9e-10 39.3 3.1 4.9e-10 39.3 3.1 2.5 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP18093.1 - 1.4e-08 34.7 7.9 1.4e-08 34.7 7.9 2.2 2 1 1 3 3 3 2 bZIP transcription factor bZIP_Maf PF03131.17 CEP18093.1 - 0.00049 20.6 3.1 0.00085 19.8 3.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 CEP18093.1 - 0.0068 15.7 1.8 0.014 14.7 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) MPS2 PF17060.5 CEP18093.1 - 0.04 13.2 0.9 0.057 12.7 0.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Cas9_REC PF16592.5 CEP18093.1 - 0.064 12.0 0.4 0.086 11.6 0.4 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 HAUS-augmin3 PF14932.6 CEP18093.1 - 0.072 12.7 3.8 0.11 12.0 3.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mvb12 PF09452.10 CEP18093.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 ATG16 PF08614.11 CEP18093.1 - 0.35 11.1 9.3 0.53 10.5 9.3 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 CEP18093.1 - 0.41 10.9 3.4 6.1 7.2 0.5 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain ZapB PF06005.12 CEP18093.1 - 0.49 10.9 4.1 0.64 10.5 3.0 1.6 1 1 1 2 2 2 0 Cell division protein ZapB Nup54 PF13874.6 CEP18093.1 - 0.53 10.4 5.3 0.78 9.8 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.12 CEP18093.1 - 1.3 9.1 8.5 6 7.0 1.3 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Ceramidase PF05875.12 CEP18094.1 - 9.5e-46 156.3 8.8 1.1e-45 156.1 8.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 CEP18094.1 - 0.025 14.5 0.7 0.099 12.6 0.7 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide HSF_DNA-bind PF00447.17 CEP18095.1 - 1.3e-31 109.1 3.0 1.3e-31 109.1 3.0 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding ImcF-related_N PF14331.6 CEP18095.1 - 0.0014 18.1 0.6 1 8.7 0.0 2.2 2 0 0 2 2 2 2 ImcF-related N-terminal domain ALMT PF11744.8 CEP18095.1 - 0.074 11.9 2.2 0.1 11.4 2.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Utp12 PF04003.12 CEP18095.1 - 0.41 11.0 2.3 0.89 9.9 1.6 1.9 1 1 1 2 2 2 0 Dip2/Utp12 Family Arch_fla_DE PF04659.13 CEP18096.1 - 0.064 13.1 0.1 0.072 13.0 0.1 1.1 1 0 0 1 1 1 0 Archaeal flagella protein AAA_22 PF13401.6 CEP18097.1 - 0.00049 20.4 0.0 0.00092 19.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CEP18097.1 - 0.0039 17.2 0.2 0.017 15.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP18097.1 - 0.012 15.4 0.2 0.017 14.8 0.2 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CEP18097.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CEP18097.1 - 0.016 15.6 0.0 0.04 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ThiF PF00899.21 CEP18097.1 - 0.033 13.6 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 ThiF family ResIII PF04851.15 CEP18097.1 - 0.059 13.4 0.1 0.27 11.2 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CEP18097.1 - 0.068 13.3 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain TK PF00265.18 CEP18097.1 - 0.07 13.0 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_30 PF13604.6 CEP18097.1 - 0.23 11.1 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF325 PF03804.13 CEP18098.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral proteins of unknown function DUF3222 PF11519.8 CEP18099.1 - 0.055 13.7 0.1 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Plant_tran PF04827.14 CEP18099.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein DAGAT PF03982.13 CEP18101.1 - 1.3e-97 326.3 0.0 1.6e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Homeodomain PF00046.29 CEP18102.1 - 1.6e-16 59.9 1.9 3.3e-16 58.9 1.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP18102.1 - 0.015 15.2 0.2 0.043 13.7 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 CEP18102.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF5606 PF18347.1 CEP18102.1 - 0.093 12.9 0.0 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5606) RRM_2 PF04059.12 CEP18103.1 - 3.1e-26 91.4 3.9 4.7e-26 90.8 2.7 2.0 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 CEP18103.1 - 0.064 13.1 0.3 1.1 9.1 0.1 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2341 PF10102.9 CEP18103.1 - 0.072 13.7 1.6 2.3 8.8 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2341) DUF4840 PF16128.5 CEP18103.1 - 0.15 12.1 2.0 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4840) Fungal_trans PF04082.18 CEP18104.1 - 3e-24 85.5 0.4 5.4e-24 84.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP18104.1 - 6.3e-10 39.0 9.6 1.4e-09 37.9 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3_PI4_kinase PF00454.27 CEP18105.1 - 4e-30 105.4 1.4 1e-27 97.5 0.0 3.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAM199X PF15814.5 CEP18105.1 - 0.00048 19.3 20.0 0.0035 16.5 4.3 2.3 2 0 0 2 2 2 2 Protein family FAM199X RLL PF10036.9 CEP18105.1 - 0.006 16.5 2.4 0.006 16.5 2.4 2.0 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein DUF4135 PF13575.6 CEP18105.1 - 0.032 13.6 1.2 0.056 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Connexin PF00029.19 CEP18105.1 - 0.47 10.2 4.2 0.22 11.3 1.3 2.0 2 0 0 2 2 2 0 Connexin AAA_23 PF13476.6 CEP18105.1 - 0.58 10.6 8.9 0.26 11.8 3.9 2.2 2 0 0 2 2 2 0 AAA domain CCSAP PF15748.5 CEP18105.1 - 1.1 9.3 19.5 0.51 10.5 4.9 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated EIIBC-GUT_N PF03612.14 CEP18105.1 - 1.2 8.9 5.9 3.1 7.5 5.9 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Rrp15p PF07890.12 CEP18105.1 - 2.8 8.3 14.7 1.4 9.2 4.6 2.5 2 0 0 2 2 2 0 Rrp15p DDE_3 PF13358.6 CEP18106.1 - 2.9e-10 40.1 0.2 4.8e-10 39.4 0.2 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease SLT PF01464.20 CEP18107.1 - 0.077 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain HTH_23 PF13384.6 CEP18108.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Nic96 PF04097.14 CEP18109.1 - 3.9e-139 465.0 15.3 5.3e-139 464.5 15.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Noc2 PF03715.13 CEP18110.1 - 2.1e-94 316.2 0.1 3.7e-94 315.3 0.1 1.4 1 0 0 1 1 1 1 Noc2p family IPK PF03770.16 CEP18110.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Inositol polyphosphate kinase Bim_N PF06773.11 CEP18110.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Bim protein N-terminus Methyltransf_24 PF13578.6 CEP18110.1 - 0.17 12.9 0.1 0.44 11.6 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain DHHC PF01529.20 CEP18111.1 - 1.7e-38 131.7 7.7 1.7e-38 131.7 7.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase QueC PF06508.13 CEP18111.1 - 0.056 12.9 2.3 0.097 12.1 2.3 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF4064 PF13273.6 CEP18111.1 - 0.33 11.2 5.5 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) RVT_1 PF00078.27 CEP18112.1 - 2.1e-30 105.9 0.0 4.4e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CEP18112.1 - 4.6e-06 26.5 0.5 1.3e-05 25.0 0.5 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CEP18112.1 - 1.2e-05 26.0 1.2 3.8e-05 24.3 1.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP18112.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.23 CEP18113.1 - 1.3e-06 28.2 19.3 3.8e-05 23.6 5.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 CEP18113.1 - 0.85 9.4 21.5 2.8 7.7 6.5 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger IMUP PF15761.5 CEP18113.1 - 0.88 10.3 14.7 3.2 8.5 7.0 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein SNF2_N PF00176.23 CEP18114.1 - 1.4e-57 195.0 0.1 2.4e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP18114.1 - 1.5e-16 60.8 0.0 9.1e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP18114.1 - 4.3e-09 36.6 0.0 4.3e-09 36.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 CEP18114.1 - 8.7e-07 29.3 0.1 8.7e-07 29.3 0.1 4.7 1 1 2 3 3 3 1 Rad54 N terminal HDA2-3 PF11496.8 CEP18114.1 - 2.5e-05 23.6 0.0 2.5e-05 23.6 0.0 2.7 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 gag_pre-integrs PF13976.6 CEP18114.1 - 0.4 10.6 2.5 0.32 10.9 0.2 2.1 2 0 0 2 2 2 0 GAG-pre-integrase domain DUF1838 PF08894.11 CEP18115.1 - 5.1e-83 278.4 0.3 7.7e-83 277.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) CUE PF02845.16 CEP18115.1 - 1.2e-11 44.0 0.0 3.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 CUE domain PhoLip_ATPase_C PF16212.5 CEP18116.1 - 5.7e-69 232.6 18.3 5.7e-69 232.6 18.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP18116.1 - 3e-22 78.1 5.8 8e-22 76.7 5.8 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEP18116.1 - 9.2e-12 44.9 0.0 7.9e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP18116.1 - 1.2e-11 45.3 0.1 5.8e-07 30.0 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP18116.1 - 4.7e-06 26.3 0.0 1.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP18116.1 - 0.00051 19.9 0.2 0.0023 17.7 0.2 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Terminase_3C PF17288.2 CEP18116.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.9 1 1 0 1 1 1 0 Terminase RNAseH like domain Glucosamine_iso PF01182.20 CEP18117.1 - 3.1e-21 76.3 0.0 4.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 CEP18118.1 - 1.1e-58 198.5 0.0 1.5e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP18118.1 - 2.3e-58 197.4 0.0 3.7e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase SAD_SRA PF02182.17 CEP18119.1 - 1.3e-37 128.9 1.8 1.5e-37 128.7 0.0 2.1 3 0 0 3 3 3 1 SAD/SRA domain Exo_endo_phos PF03372.23 CEP18119.1 - 1.9e-20 73.4 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_3 PF13920.6 CEP18119.1 - 0.00026 20.8 13.5 0.00026 20.8 13.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.23 CEP18119.1 - 0.00049 19.8 0.4 0.022 14.5 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family zf-C3HC4_4 PF15227.6 CEP18119.1 - 0.00065 19.8 8.3 0.00065 19.8 8.3 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CEP18119.1 - 0.0031 17.4 13.3 0.0031 17.4 13.3 3.0 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEP18119.1 - 0.0032 17.3 13.2 0.0032 17.3 13.2 2.9 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 Sugar_tr PF00083.24 CEP18120.1 - 3.1e-98 329.6 32.2 6.9e-52 176.8 5.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP18120.1 - 1.8e-24 86.3 31.7 1.8e-24 86.3 31.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 CEP18121.1 - 2.7e-10 40.1 23.0 2.7e-05 24.3 0.4 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP18121.1 - 1.2e-07 31.8 18.5 1.9e-05 24.8 2.2 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf_ZIC PF18366.1 CEP18121.1 - 3e-05 24.0 5.7 0.0012 18.9 0.1 4.4 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 CEP18121.1 - 8.9e-05 23.0 20.9 0.014 16.2 0.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.18 CEP18121.1 - 0.0038 17.9 3.0 0.0056 17.4 1.9 1.9 1 1 1 2 2 2 1 TRAF-type zinc finger zf-C2H2_8 PF15909.5 CEP18121.1 - 0.015 15.6 6.9 3.4 8.0 4.6 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP18121.1 - 0.058 14.0 0.7 0.058 14.0 0.7 5.9 3 2 1 4 4 4 0 FOXP coiled-coil domain DDE_3 PF13358.6 CEP18122.1 - 3.2e-15 56.1 0.3 5.9e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP18122.1 - 6.7e-14 51.9 0.3 1.3e-13 50.9 0.3 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP18122.1 - 1.4e-05 25.6 0.7 2.5e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain LacI PF00356.21 CEP18122.1 - 0.1 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PigN PF04987.14 CEP18123.1 - 7.7e-138 460.2 45.7 1.1e-137 459.7 45.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CEP18123.1 - 5.1e-10 39.5 0.4 2.4e-09 37.3 0.4 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SLATT_fungal PF18142.1 CEP18123.1 - 0.015 15.3 0.2 0.039 13.9 0.2 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Nop14 PF04147.12 CEP18124.1 - 4.6 5.3 9.0 8.6 4.4 9.0 1.3 1 0 0 1 1 1 0 Nop14-like family Cys_Met_Meta_PP PF01053.20 CEP18125.1 - 2.2e-140 467.5 0.0 3.9e-90 302.1 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CEP18125.1 - 1.7e-10 40.7 0.0 2.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CEP18125.1 - 6.8e-08 31.9 0.1 1e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEP18125.1 - 3.3e-07 29.9 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CEP18125.1 - 1.4e-05 24.6 0.0 4.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase SelA PF03841.13 CEP18125.1 - 0.0021 17.1 0.1 0.028 13.4 0.0 2.4 2 1 0 2 2 2 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.11 CEP18125.1 - 0.0029 16.2 0.0 0.0046 15.5 0.0 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 CEP18125.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein ADH_zinc_N PF00107.26 CEP18125.1 - 0.14 12.1 0.0 0.95 9.4 0.0 2.3 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Radical_SAM PF04055.21 CEP18125.1 - 0.19 12.1 0.1 6 7.2 0.0 2.6 2 1 0 3 3 3 0 Radical SAM superfamily Rep_fac-A_C PF08646.10 CEP18126.1 - 1.5e-49 167.5 12.6 5.3e-48 162.5 6.5 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CEP18126.1 - 2.9e-32 110.5 1.2 1.1e-31 108.6 0.2 2.5 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 CEP18126.1 - 1.7e-20 72.9 0.8 5.7e-20 71.2 0.8 2.0 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CEP18126.1 - 3.4e-13 49.4 0.3 2e-09 37.3 0.0 3.5 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CEP18126.1 - 8.2e-08 32.2 0.6 0.00062 19.5 0.1 2.9 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 CEP18126.1 - 0.00097 19.4 0.3 0.00097 19.4 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function DUF223 DUF4539 PF15072.6 CEP18126.1 - 0.0033 17.4 0.6 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) zinc-ribbons_6 PF07191.12 CEP18126.1 - 0.012 15.6 2.6 0.016 15.2 1.3 1.9 2 0 0 2 2 2 0 zinc-ribbons DUF2141 PF09912.9 CEP18126.1 - 0.071 13.0 0.3 0.9 9.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) Ribosomal_L37ae PF01780.19 CEP18126.1 - 0.59 10.2 3.3 0.5 10.5 0.9 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family ATG22 PF11700.8 CEP18127.1 - 4.7e-103 345.4 26.9 5.4e-103 345.2 26.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CEP18127.1 - 7.1e-16 58.1 34.0 2.2e-06 26.9 6.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF485 PF04341.12 CEP18128.1 - 0.11 12.4 2.9 0.2 11.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Asp PF00026.23 CEP18130.1 - 5.9e-52 177.0 2.2 1.5e-51 175.8 2.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CEP18130.1 - 1.5e-09 38.4 4.5 7.8e-08 32.8 4.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CEP18130.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal IFRD PF05004.13 CEP18131.1 - 1.4e-54 185.3 7.0 1.4e-54 185.3 7.0 1.5 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) DHR-2 PF06920.13 CEP18131.1 - 0.085 11.5 0.5 0.12 10.9 0.5 1.3 1 0 0 1 1 1 0 Dock homology region 2 ZapB PF06005.12 CEP18131.1 - 0.2 12.1 3.4 0.47 10.9 3.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Xan_ur_permease PF00860.20 CEP18132.1 - 5.5e-58 196.5 27.5 8.3e-57 192.6 27.5 2.0 1 1 0 1 1 1 1 Permease family MPC PF03650.13 CEP18132.1 - 0.013 15.6 0.6 0.047 13.8 0.1 2.1 2 1 1 3 3 3 0 Mitochondrial pyruvate carriers Glyco_hydro_18 PF00704.28 CEP18133.1 - 2.7e-81 273.7 0.7 3.1e-81 273.5 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ATP_sub_h PF10775.9 CEP18134.1 - 5.6e-23 80.7 2.2 7e-23 80.4 2.2 1.1 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 CEP18134.1 - 0.033 14.6 0.0 0.04 14.3 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Oxidored_FMN PF00724.20 CEP18135.1 - 8.9e-73 245.5 0.0 1.1e-72 245.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 CEP18135.1 - 0.003 16.7 0.2 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) ArfGap PF01412.18 CEP18136.1 - 5e-37 126.6 3.3 5e-37 126.6 3.3 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Peptidase_M24_C PF16188.5 CEP18138.1 - 0.14 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 WAC_Acf1_DNA_bd PF10537.9 CEP18139.1 - 2e-24 86.1 1.3 2e-24 86.1 1.3 2.8 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CEP18139.1 - 5.1e-24 84.6 0.3 5.1e-24 84.6 0.3 4.0 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif TBCA PF02970.16 CEP18139.1 - 7.7e-18 64.6 6.5 7.7e-18 64.6 6.5 5.1 5 0 0 5 5 5 1 Tubulin binding cofactor A DDT PF02791.17 CEP18139.1 - 9.9e-11 41.8 0.2 2.4e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 CEP18139.1 - 1.7e-06 27.4 0.0 3.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WLM PF08325.10 CEP18140.1 - 7e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 CEP18140.1 - 3e-14 52.5 1.9 7.8e-14 51.2 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 CEP18140.1 - 0.0072 16.8 0.1 0.019 15.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF45 PF01863.17 CEP18140.1 - 0.65 10.0 5.0 0.16 12.0 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF5456 PF17539.2 CEP18141.1 - 0.0022 17.9 0.2 0.0027 17.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5456) CP2 PF04516.15 CEP18141.1 - 0.021 14.1 0.4 0.026 13.8 0.4 1.1 1 0 0 1 1 1 0 CP2 transcription factor Glyco_hydro_85 PF03644.13 CEP18142.1 - 1.1e-96 323.8 2.8 1.8e-96 323.1 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 POT1PC PF16686.5 CEP18143.1 - 2.2e-09 37.4 0.2 1.3e-08 34.8 0.2 2.1 1 1 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CEP18143.1 - 5.4e-09 36.0 0.1 8.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 DUF5454 PF17535.2 CEP18143.1 - 0.073 12.5 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5454) efThoc1 PF11957.8 CEP18144.1 - 8.6e-84 281.9 1.8 1.7e-83 281.0 0.2 1.9 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor ResIII PF04851.15 CEP18144.1 - 0.1 12.6 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Hen1_Lam_C PF18441.1 CEP18144.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain Thaumatin PF00314.17 CEP18145.1 - 2.9e-49 167.6 11.7 1.8e-48 165.0 11.7 1.8 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CEP18145.1 - 0.036 13.3 3.5 4.9 6.3 1.4 2.9 2 1 0 2 2 2 0 Beta-1,3-glucanase Pkinase PF00069.25 CEP18146.1 - 4e-75 252.6 0.0 5.9e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18146.1 - 3.4e-41 141.3 0.0 4.7e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP18146.1 - 0.00023 20.0 0.0 0.00095 18.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEP18146.1 - 0.00026 20.4 0.0 0.00061 19.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CEP18146.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CEP18146.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CEP18146.1 - 0.1 12.2 0.1 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 L27_2 PF09045.10 CEP18146.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 L27_2 RNA_pol_Rpb4 PF03874.16 CEP18147.1 - 1.2e-25 90.3 7.0 1.5e-25 89.9 7.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HBD PF18534.1 CEP18147.1 - 0.0031 17.6 0.8 0.0064 16.6 0.8 1.7 1 1 0 1 1 1 1 Helical bundle domain T3SS_needle_F PF09392.10 CEP18147.1 - 0.042 14.0 0.3 0.1 12.8 0.3 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF RVT_N PF13655.6 CEP18148.1 - 2.7 8.3 7.4 1.6 9.0 3.7 2.7 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DUF3924 PF13062.6 CEP18148.1 - 3.4 7.7 7.1 0.36 10.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3924) Amidase PF01425.21 CEP18148.1 - 6.8 5.5 6.7 14 4.4 6.7 1.6 1 0 0 1 1 1 0 Amidase FAM184 PF15665.5 CEP18148.1 - 7.7 6.2 70.1 3.9 7.2 28.9 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B DHHC PF01529.20 CEP18149.1 - 8.1e-12 45.4 12.2 1.1e-11 45.0 12.2 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase PAP1 PF08601.10 CEP18151.1 - 1.3e-14 54.7 0.4 1.3e-14 54.7 0.4 3.0 1 1 2 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 CEP18151.1 - 7.6e-09 35.5 16.2 2.5e-08 33.9 16.2 1.9 1 1 0 1 1 1 1 bZIP transcription factor SUI1 PF01253.22 CEP18151.1 - 0.025 15.1 0.2 0.065 13.8 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor SUI1 bZIP_2 PF07716.15 CEP18151.1 - 0.49 10.5 19.1 6.1 7.0 19.1 2.4 1 1 0 1 1 1 0 Basic region leucine zipper DUF5327 PF17261.2 CEP18151.1 - 3.1 8.6 16.3 2.3 9.0 0.0 3.6 2 1 1 3 3 3 0 Family of unknown function (DUF5327) TPR_MLP1_2 PF07926.12 CEP18152.1 - 0.0039 17.3 3.0 0.0039 17.3 3.0 4.2 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 CEP18152.1 - 0.011 15.2 2.7 0.011 15.2 2.7 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 5 Thiolase_N PF00108.23 CEP18153.1 - 1.6e-87 293.1 3.9 5.5e-87 291.4 3.9 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CEP18153.1 - 4.4e-41 139.4 0.4 4.4e-41 139.4 0.4 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CEP18153.1 - 1.8e-05 24.5 2.9 2e-05 24.3 1.3 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CEP18153.1 - 0.12 12.3 5.1 0.35 10.7 0.2 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_1 PF00583.25 CEP18155.1 - 5.7e-06 26.6 0.0 1.8e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP18155.1 - 0.02 14.8 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP18155.1 - 0.047 14.1 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dimer_Tnp_Tn5 PF02281.16 CEP18155.1 - 0.06 13.1 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain WHIM1 PF15612.6 CEP18155.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 MFS_1 PF07690.16 CEP18156.1 - 7.9e-52 176.3 41.8 1e-35 123.3 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CEP18156.1 - 9.3e-06 24.5 30.4 0.00038 19.2 12.9 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 CEP18156.1 - 3.2e-05 22.4 19.9 9.4e-05 20.9 0.7 3.7 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 CEP18156.1 - 4.3e-05 22.1 27.2 0.0022 16.5 8.5 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector MFS_4 PF06779.14 CEP18156.1 - 0.0035 16.7 25.1 0.029 13.7 8.5 2.9 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FAD-oxidase_C PF02913.19 CEP18157.1 - 3e-56 190.8 0.2 3.8e-56 190.5 0.2 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEP18157.1 - 2e-36 124.8 0.2 4.4e-36 123.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.27 CEP18158.1 - 8.2e-67 221.2 4.6 3.2e-23 81.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP18158.1 - 0.15 11.1 1.1 0.93 8.6 0.1 2.6 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Ribosomal_L23 PF00276.20 CEP18159.1 - 1.9e-18 66.6 1.6 2.7e-18 66.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 TrbH PF07283.11 CEP18159.1 - 0.047 13.9 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein TrbH zf-C2H2 PF00096.26 CEP18160.1 - 1.2e-10 41.2 22.1 0.00014 22.1 1.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP18160.1 - 2.7e-08 33.9 20.1 0.018 15.9 0.9 3.9 3 1 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP18160.1 - 7.2e-06 26.2 30.3 2.1e-05 24.7 3.6 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CEP18160.1 - 0.00079 19.1 22.0 0.45 10.3 0.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc-finger domain FOXP-CC PF16159.5 CEP18160.1 - 0.0095 16.5 5.4 0.18 12.5 0.3 2.7 3 0 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CEP18160.1 - 0.065 13.5 6.4 7.1 7.1 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP18160.1 - 0.14 12.6 3.2 4.7 7.8 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 CEP18160.1 - 4.2 7.6 7.0 32 4.7 0.6 3.6 4 0 0 4 4 4 0 Zic proteins zinc finger domain Peptidase_S8 PF00082.22 CEP18161.1 - 1.7e-28 99.7 9.7 7.6e-27 94.3 0.4 2.2 1 1 1 2 2 2 2 Subtilase family Ribosomal_S11 PF00411.19 CEP18162.1 - 4.3e-23 81.8 0.1 4.3e-23 81.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S11 SF3A2 PF16835.5 CEP18163.1 - 8.7e-40 135.0 0.2 1.4e-39 134.4 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CEP18163.1 - 1.1e-07 31.9 1.7 1.1e-07 31.9 1.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CEP18163.1 - 2.6e-05 24.1 0.5 4.3e-05 23.4 0.5 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 CEP18163.1 - 0.016 14.7 0.9 0.03 13.9 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CENP-P PF13096.6 CEP18164.1 - 0.011 15.5 0.2 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P TFIIA PF03153.13 CEP18164.1 - 0.048 13.7 28.1 0.061 13.3 26.9 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 CEP18164.1 - 1.4 8.2 26.5 2.1 7.6 26.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CEP18164.1 - 2 6.5 30.6 2.7 6.1 30.6 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 CEP18164.1 - 4.4 6.4 7.1 6.4 5.9 7.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-RVT PF13966.6 CEP18166.1 - 2.2e-08 34.7 0.3 3.6e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Mito_carr PF00153.27 CEP18167.1 - 3.8e-71 235.1 6.1 4.4e-27 93.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP18167.1 - 0.0021 17.2 4.9 1.3 8.1 0.0 3.9 1 1 4 5 5 5 2 Gammaproteobacterial serine protease PrcB_C PF14343.6 CEP18167.1 - 0.012 15.7 1.3 30 4.9 0.1 3.5 3 0 0 3 3 3 0 PrcB C-terminal TT_ORF1 PF02956.14 CEP18167.1 - 0.06 12.0 0.3 0.086 11.5 0.3 1.2 1 0 0 1 1 1 0 TT viral orf 1 PTR2 PF00854.21 CEP18168.1 - 3.7e-90 302.6 14.7 5.3e-90 302.1 14.7 1.3 1 0 0 1 1 1 1 POT family DUF4231 PF14015.6 CEP18168.1 - 0.015 15.8 0.5 0.015 15.8 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3087 PF11286.8 CEP18168.1 - 0.042 13.3 0.3 0.085 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DOT1 PF08123.13 CEP18169.1 - 4.5e-68 228.8 0.1 8.7e-68 227.9 0.1 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 SWIRM-assoc_2 PF16496.5 CEP18169.1 - 6.8e-36 124.0 0.0 6.8e-36 124.0 0.0 3.4 3 0 0 3 3 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 CEP18169.1 - 8.1e-28 96.6 0.1 8.1e-28 96.6 0.1 2.7 3 0 0 3 3 2 1 SWIRM domain Myb_DNA-binding PF00249.31 CEP18169.1 - 3.8e-09 36.6 0.1 3.8e-09 36.6 0.1 2.0 2 0 0 2 2 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP18169.1 - 2.7e-06 27.6 0.2 1.1e-05 25.6 0.2 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CEP18169.1 - 5.2e-06 26.3 8.8 5.2e-06 26.3 8.8 3.6 3 0 0 3 3 2 1 SWIRM-associated region 1 Methyltransf_25 PF13649.6 CEP18169.1 - 8.2e-05 23.2 0.0 0.00029 21.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18169.1 - 0.00024 20.9 0.0 0.00024 20.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP18169.1 - 0.001 19.7 0.0 0.0034 18.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain BRCT_2 PF16589.5 CEP18169.1 - 0.0087 16.5 0.2 0.23 11.9 0.2 3.4 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Methyltransf_12 PF08242.12 CEP18169.1 - 0.01 16.5 1.7 0.023 15.4 0.0 2.6 2 0 0 2 2 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CEP18169.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ABC_export PF16962.5 CEP18170.1 - 0.0056 15.2 2.7 0.0069 14.9 2.7 1.1 1 0 0 1 1 1 1 Putative ABC exporter MARVEL PF01284.23 CEP18170.1 - 0.0099 15.9 9.3 0.016 15.3 9.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain RDD PF06271.12 CEP18170.1 - 0.061 13.5 3.7 0.26 11.5 0.5 2.1 2 0 0 2 2 2 0 RDD family TssN PF17555.2 CEP18170.1 - 0.95 8.8 8.3 1.4 8.2 8.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF5563 PF17718.1 CEP18171.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5563) RRM_1 PF00076.22 CEP18172.1 - 4.1e-14 52.2 0.0 7.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeodomain PF00046.29 CEP18173.1 - 8e-14 51.2 5.0 1.7e-13 50.2 5.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP18173.1 - 0.0068 16.3 1.0 0.018 15.0 1.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF2730 PF10805.8 CEP18173.1 - 0.65 10.1 2.9 0.57 10.3 0.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) TLP-20 PF06088.11 CEP18173.1 - 2.1 8.2 8.0 0.9 9.4 5.4 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TraC PF07820.12 CEP18173.1 - 4.2 7.8 8.0 5.3 7.5 0.6 2.9 1 1 2 3 3 3 0 TraC-like protein LIM PF00412.22 CEP18175.1 - 2.5e-20 72.5 27.9 1.6e-07 31.4 5.1 4.1 3 1 0 3 3 3 3 LIM domain MerR_2 PF13591.6 CEP18176.1 - 0.096 12.6 1.5 0.33 10.8 1.5 1.9 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF3385 PF11865.8 CEP18176.1 - 3 7.7 8.7 2.6 7.9 2.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) SAC3_GANP PF03399.16 CEP18177.1 - 9.4e-20 71.2 7.1 5.1e-18 65.5 7.1 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CEP18177.1 - 0.0021 18.0 1.5 0.0028 17.6 0.2 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family HlyD_3 PF13437.6 CEP18177.1 - 0.096 13.4 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein zf-CCHC_6 PF15288.6 CEP18179.1 - 0.15 11.9 0.3 0.15 11.9 0.3 1.6 2 0 0 2 2 2 0 Zinc knuckle AAA PF00004.29 CEP18180.1 - 6.8e-38 130.1 0.0 1.5e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CEP18180.1 - 8.1e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CEP18180.1 - 1.2e-06 28.9 0.6 0.0052 17.1 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 CEP18180.1 - 1.8e-06 28.4 0.2 5.7e-05 23.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CEP18180.1 - 3.6e-06 27.0 0.0 1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEP18180.1 - 4.9e-06 26.4 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEP18180.1 - 1.1e-05 25.5 0.1 9.4e-05 22.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CEP18180.1 - 3.9e-05 23.8 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 CEP18180.1 - 0.0001 21.8 0.2 0.45 9.9 0.0 3.1 3 1 1 4 4 4 2 Bacterial TniB protein AAA_18 PF13238.6 CEP18180.1 - 0.00012 22.6 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP18180.1 - 0.00018 21.7 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CEP18180.1 - 0.00057 19.3 0.2 0.0015 17.9 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CEP18180.1 - 0.00089 19.2 0.1 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 CEP18180.1 - 0.00092 19.6 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 CEP18180.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 CEP18180.1 - 0.0019 18.1 0.1 0.011 15.7 0.0 2.2 1 1 1 2 2 2 1 NACHT domain ABC_tran PF00005.27 CEP18180.1 - 0.0027 18.2 0.0 0.0077 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CEP18180.1 - 0.0035 17.1 0.0 0.0059 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 CEP18180.1 - 0.0036 17.0 0.0 0.07 12.8 0.0 2.7 2 1 2 4 4 4 1 Guanylate kinase TIP49 PF06068.13 CEP18180.1 - 0.0039 16.4 0.0 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 CEP18180.1 - 0.0043 17.3 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CEP18180.1 - 0.0069 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain ATPase PF06745.13 CEP18180.1 - 0.0085 15.5 0.0 0.15 11.4 0.0 2.3 1 1 1 2 2 2 1 KaiC TsaE PF02367.17 CEP18180.1 - 0.0086 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CEP18180.1 - 0.011 15.3 0.3 0.055 13.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CEP18180.1 - 0.011 15.6 0.1 0.8 9.5 0.1 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Bac_DnaA PF00308.18 CEP18180.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.6 CEP18180.1 - 0.016 15.6 0.1 0.042 14.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CEP18180.1 - 0.016 15.1 0.0 0.062 13.2 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 CEP18180.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CEP18180.1 - 0.027 14.0 0.1 0.061 12.8 0.0 1.7 2 1 0 2 2 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CEP18180.1 - 0.034 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CEP18180.1 - 0.038 13.7 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CEP18180.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEP18180.1 - 0.05 12.9 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 CEP18180.1 - 0.052 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA_lig_kinase PF08303.11 CEP18180.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Hydin_ADK PF17213.3 CEP18180.1 - 0.088 13.1 0.3 0.83 9.9 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CPT PF07931.12 CEP18180.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.6 CEP18180.1 - 0.15 12.1 0.2 0.66 10.1 0.0 2.2 2 1 0 2 2 1 0 Cytidylate kinase-like family SWIM PF04434.17 CEP18181.1 - 0.009 15.7 0.6 0.014 15.0 0.6 1.3 1 0 0 1 1 1 1 SWIM zinc finger Menin PF05053.13 CEP18181.1 - 1.5 7.1 7.7 3 6.1 7.7 1.4 1 0 0 1 1 1 0 Menin Phage_ABA_S PF18066.1 CEP18182.1 - 0.054 14.2 0.1 0.093 13.4 0.1 1.5 1 0 0 1 1 1 0 Phage ABA sandwich domain KduI PF04962.12 CEP18182.1 - 0.09 12.1 2.5 0.15 11.4 2.5 1.2 1 0 0 1 1 1 0 KduI/IolB family MatE PF01554.18 CEP18183.1 - 4.5e-61 205.2 25.4 2.5e-33 115.0 9.7 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CEP18183.1 - 4e-06 27.0 21.0 7.9e-06 26.0 8.5 4.0 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF2269 PF10027.9 CEP18183.1 - 0.0017 18.4 0.3 0.0017 18.4 0.3 2.8 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) UPF0242 PF06785.11 CEP18183.1 - 0.0056 16.8 0.2 0.0056 16.8 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus ING PF12998.7 CEP18184.1 - 0.0026 18.3 0.3 0.0026 18.3 0.3 2.1 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Oxidored_nitro PF00148.19 CEP18184.1 - 0.21 10.3 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TUSC2 PF15000.6 CEP18185.1 - 0.016 15.5 1.1 0.088 13.1 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor candidate 2 DUF104 PF01954.16 CEP18185.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 G-patch PF01585.23 CEP18186.1 - 9.8e-12 44.6 5.1 1.3e-11 44.1 3.5 2.1 2 1 1 3 3 3 1 G-patch domain G-patch_2 PF12656.7 CEP18186.1 - 0.036 14.1 2.7 0.059 13.5 1.2 2.1 1 1 1 2 2 2 0 G-patch domain zf-CCCH PF00642.24 CEP18186.1 - 0.31 11.0 2.5 0.56 10.2 2.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidohydro_1 PF01979.20 CEP18187.1 - 2.3e-20 73.2 0.1 2.2e-19 70.0 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CEP18187.1 - 7.6e-12 45.4 0.3 3.9e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family ALG3 PF05208.13 CEP18188.1 - 3.5e-138 460.9 22.5 4.3e-138 460.6 22.5 1.0 1 0 0 1 1 1 1 ALG3 protein AAA PF00004.29 CEP18191.1 - 6.4e-14 52.5 0.1 2.2e-13 50.7 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CEP18191.1 - 3.5e-12 46.8 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP18191.1 - 3.2e-11 43.9 0.1 5e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 CEP18191.1 - 1.2e-10 41.2 0.6 3.2e-10 39.8 0.6 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 CEP18191.1 - 1.4e-05 25.2 0.2 1.4e-05 25.2 0.2 2.5 3 0 0 3 3 2 1 AAA lid domain NACHT PF05729.12 CEP18191.1 - 4e-05 23.6 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 CEP18191.1 - 8.9e-05 21.9 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CEP18191.1 - 9.5e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP18191.1 - 0.00024 21.5 0.1 0.0006 20.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CEP18191.1 - 0.00073 18.8 0.3 0.0014 17.9 0.3 1.4 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 CEP18191.1 - 0.0028 17.6 0.1 0.0064 16.4 0.1 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEP18191.1 - 0.0031 18.1 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CEP18191.1 - 0.022 14.4 0.4 0.068 12.8 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CEP18191.1 - 0.037 13.9 0.2 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 CEP18191.1 - 0.051 13.7 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CEP18191.1 - 0.058 13.8 0.2 0.3 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain dbPDZ_assoc PF16610.5 CEP18191.1 - 0.15 12.3 5.5 0.44 10.8 5.5 1.8 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 CLP1_P PF16575.5 CEP18191.1 - 0.37 10.6 3.6 0.9 9.3 0.3 2.7 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Pkinase PF00069.25 CEP18192.1 - 5.7e-51 173.4 0.0 1.4e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18192.1 - 2.5e-19 69.6 0.0 4.7e-19 68.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEP18192.1 - 0.0004 19.8 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP18192.1 - 0.0051 16.2 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF4476 PF14771.6 CEP18192.1 - 0.019 15.3 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Choline_kinase PF01633.20 CEP18192.1 - 0.027 14.1 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CEP18192.1 - 0.044 13.4 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CEP18192.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family RCDG1 PF15725.5 CEP18192.1 - 6.2 7.3 20.1 5.7 7.4 8.3 2.5 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein ABC_tran PF00005.27 CEP18193.1 - 1e-25 90.8 0.0 1.5e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CEP18193.1 - 6.6e-09 36.0 0.0 0.00012 22.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CEP18193.1 - 0.00059 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP18193.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 CEP18193.1 - 0.0014 18.2 0.0 0.0062 16.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEP18193.1 - 0.0015 18.2 0.0 0.0044 16.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP18193.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase Mg_chelatase PF01078.21 CEP18193.1 - 0.0018 17.7 0.0 0.0098 15.3 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CEP18193.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CEP18193.1 - 0.0024 17.8 0.2 0.04 13.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 CEP18193.1 - 0.0029 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CEP18193.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 CEP18193.1 - 0.0034 17.5 0.1 0.0044 17.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CEP18193.1 - 0.004 17.7 0.0 0.0065 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CEP18193.1 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CEP18193.1 - 0.026 14.5 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CEP18193.1 - 0.036 14.6 0.0 0.053 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain CBM39 PF15886.5 CEP18193.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) cobW PF02492.19 CEP18193.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CEP18193.1 - 0.11 13.0 0.2 0.29 11.6 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CEP18193.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain ABC_ATPase PF09818.9 CEP18193.1 - 0.14 10.9 0.1 13 4.4 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 CEP18193.1 - 0.14 12.4 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CEP18193.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase_2 PF01637.18 CEP18193.1 - 0.23 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CEP18193.1 - 0.23 10.5 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-H2C2_2 PF13465.6 CEP18194.1 - 1.1e-10 41.4 10.8 7.3e-09 35.7 1.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP18194.1 - 2e-09 37.4 11.0 7.4e-06 26.1 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP18194.1 - 1.4e-08 34.9 9.1 0.00093 19.8 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP18194.1 - 2.1e-05 24.7 0.9 0.075 13.3 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP18194.1 - 3.7e-05 24.0 4.3 0.12 12.8 0.2 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CEP18194.1 - 0.022 15.0 4.3 0.09 13.1 4.5 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 CEP18194.1 - 0.037 14.5 2.5 6.2 7.4 0.7 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TRAF6_Z2 PF18048.1 CEP18194.1 - 0.076 13.1 0.9 2.6 8.2 0.1 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DUF2225 PF09986.9 CEP18194.1 - 0.087 12.5 5.9 1 9.0 1.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 CEP18194.1 - 0.11 12.4 1.5 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 CEP18194.1 - 0.12 12.4 3.8 2.1 8.5 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CEP18194.1 - 0.15 12.4 11.6 0.19 12.1 2.7 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 CEP18194.1 - 0.17 11.8 9.1 0.1 12.5 2.8 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 CEP18194.1 - 0.17 11.7 6.9 2 8.3 0.8 2.3 1 1 1 2 2 2 0 GAGA factor zf_ZIC PF18366.1 CEP18194.1 - 0.2 11.8 1.0 3.4 7.8 0.1 2.5 1 1 1 2 2 2 0 Zic proteins zinc finger domain Prok-RING_1 PF14446.6 CEP18194.1 - 0.21 11.6 3.8 16 5.5 0.3 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_11 PF16622.5 CEP18194.1 - 0.68 9.8 7.0 6.1 6.7 0.7 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 CEP18194.1 - 1.7 8.6 8.4 5.9 6.9 8.4 1.9 1 1 0 1 1 1 0 SprT-like zinc ribbon domain PAS_3 PF08447.12 CEP18195.1 - 1.1e-07 32.0 0.1 0.0058 16.9 0.1 2.3 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 CEP18195.1 - 0.1 12.8 0.0 8.2 6.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain Metallophos PF00149.28 CEP18196.1 - 1.2e-38 133.7 0.2 1.7e-38 133.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CEP18196.1 - 5.1e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Zds_C PF08632.10 CEP18197.1 - 1.2e-10 41.0 1.0 7.3e-10 38.5 0.4 2.2 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term RNA_pol PF00940.19 CEP18198.1 - 4.8e-184 612.0 0.0 6.7e-184 611.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CEP18198.1 - 1.6e-101 340.1 0.0 3.6e-101 338.9 0.0 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 CEP18198.1 - 2.6e-06 27.5 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family ParA PF10609.9 CEP18199.1 - 1.3e-99 332.6 0.0 1.7e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CEP18199.1 - 4.4e-09 36.5 0.0 1.2e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CEP18199.1 - 2.5e-05 24.3 0.0 9.9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CEP18199.1 - 9.3e-05 21.7 0.1 0.00057 19.2 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 CEP18199.1 - 0.0023 17.8 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEP18199.1 - 0.0079 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CEP18199.1 - 0.013 15.4 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 CEP18199.1 - 0.019 14.4 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TF_Zn_Ribbon PF08271.12 CEP18199.1 - 0.031 13.8 0.5 0.079 12.5 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding CBP_BcsQ PF06564.12 CEP18199.1 - 0.037 13.5 0.1 0.18 11.3 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MipZ PF09140.11 CEP18199.1 - 0.042 13.1 0.1 0.088 12.1 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 CEP18199.1 - 0.059 13.8 0.1 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SNARE PF05739.19 CEP18200.1 - 3.2e-07 30.2 0.7 3.2e-07 30.2 0.7 2.6 3 0 0 3 3 3 1 SNARE domain FemAB PF02388.16 CEP18200.1 - 0.26 10.1 6.3 0.37 9.6 2.4 2.0 2 0 0 2 2 2 0 FemAB family MutS_IV PF05190.18 CEP18200.1 - 0.52 10.7 5.0 0.33 11.3 0.9 2.5 2 1 0 2 2 2 0 MutS family domain IV FUSC-like PF12805.7 CEP18200.1 - 0.85 8.6 3.7 0.2 10.7 0.4 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS TBCA PF02970.16 CEP18200.1 - 1.7 9.0 12.2 0.084 13.2 2.1 2.9 2 2 0 2 2 2 0 Tubulin binding cofactor A Pkinase PF00069.25 CEP18201.1 - 2.4e-66 223.8 0.0 3.7e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18201.1 - 1.1e-31 110.0 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP18201.1 - 3.6e-11 43.6 5.8 3.6e-11 43.6 5.8 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CEP18201.1 - 1.4e-07 30.8 0.0 2.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 CEP18201.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF3127 PF11325.8 CEP18201.1 - 0.027 14.7 0.2 0.073 13.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) CAF1A PF12253.8 CEP18201.1 - 0.27 11.4 3.2 0.96 9.7 3.2 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A PDEase_I PF00233.19 CEP18202.1 - 1.5e-75 254.0 0.4 1.5e-75 254.0 0.4 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase LAG1-DNAbind PF09271.11 CEP18203.1 - 1.7e-41 142.4 8.0 1.2e-22 81.1 0.0 3.8 3 1 1 4 4 4 2 LAG1, DNA binding BTD PF09270.10 CEP18203.1 - 1.6e-23 83.6 0.1 4.5e-21 75.7 0.0 3.8 2 1 0 2 2 2 1 Beta-trefoil DNA-binding domain Polysacc_deac_1 PF01522.21 CEP18204.1 - 1.1e-26 93.1 0.0 1.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 CEP18204.1 - 0.00056 19.6 0.1 0.006 16.3 0.0 1.9 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Hexokinase_2 PF03727.16 CEP18205.1 - 8e-59 199.0 0.2 1e-58 198.6 0.2 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CEP18205.1 - 3.7e-50 170.6 0.0 5.4e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Nsp1_C PF05064.13 CEP18205.1 - 0.034 14.0 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Adaptin_N PF01602.20 CEP18206.1 - 9.7e-145 483.1 11.6 1.2e-144 482.8 11.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CEP18206.1 - 9.3e-58 194.8 6.9 8.2e-56 188.5 1.3 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CEP18206.1 - 3.4e-18 65.8 0.9 7.3e-08 32.7 0.0 6.2 1 1 6 7 7 7 5 HEAT repeats HEAT PF02985.22 CEP18206.1 - 9.8e-10 37.9 5.7 0.0045 17.1 0.0 6.2 8 0 0 8 8 7 2 HEAT repeat Cnd3 PF12719.7 CEP18206.1 - 7.8e-07 28.6 1.2 5e-05 22.6 0.3 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CEP18206.1 - 0.00012 21.7 0.4 0.023 14.3 0.1 3.5 3 1 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 CEP18206.1 - 0.00013 22.4 0.1 0.59 10.7 0.0 4.9 4 1 1 5 5 4 1 HEAT-like repeat RTP1_C1 PF10363.9 CEP18206.1 - 0.00035 20.7 3.2 3.1 8.0 0.1 5.0 1 1 3 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 CEP18206.1 - 0.00082 19.4 0.9 1.4 8.9 0.0 3.3 2 1 1 3 3 3 2 Myosin-binding striated muscle assembly central Arm PF00514.23 CEP18206.1 - 0.0019 18.2 2.8 2.8 8.1 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CEP18206.1 - 0.011 15.7 1.2 4.5 7.4 0.0 3.5 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain GlutR_dimer PF00745.20 CEP18206.1 - 0.012 16.0 0.2 9.4 6.8 0.0 3.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phage_TAC_12 PF12363.8 CEP18206.1 - 0.12 12.8 1.6 29 5.1 0.0 3.6 4 0 0 4 4 4 0 Phage tail assembly chaperone protein, TAC Sec7_N PF12783.7 CEP18206.1 - 0.19 11.7 3.4 0.18 11.7 0.2 2.7 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Myelin_MBP PF01669.17 CEP18207.1 - 0.05 14.2 0.1 0.085 13.5 0.1 1.3 1 0 0 1 1 1 0 Myelin basic protein SNase PF00565.17 CEP18208.1 - 2.2e-66 221.1 0.3 3.4e-20 72.5 0.0 5.2 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CEP18208.1 - 1.7e-28 99.1 0.0 3.9e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Tudor domain VasI PF11319.8 CEP18208.1 - 0.074 12.7 0.1 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF4154 PF13689.6 CEP18208.1 - 0.13 12.5 0.1 0.42 10.8 0.1 1.8 1 0 0 1 1 1 0 YfiR/HmsC-like Glyco_transf_20 PF00982.21 CEP18209.1 - 9.2e-162 539.0 0.0 1.3e-161 538.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP18209.1 - 1.4e-74 250.2 0.1 2.3e-74 249.4 0.1 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 CEP18209.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain GPI-anchored PF10342.9 CEP18211.1 - 9.9e-11 42.3 0.2 9.9e-11 42.3 0.2 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.17 CEP18211.1 - 7.4 6.6 18.7 17 5.4 17.7 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein AA_permease PF00324.21 CEP18212.1 - 6.3e-134 447.1 45.5 7.2e-134 447.0 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CEP18212.1 - 7.2e-45 153.6 51.2 9.5e-45 153.2 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L12 PF00542.19 CEP18213.1 - 1.6e-21 76.4 11.7 3.5e-21 75.3 9.7 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CEP18213.1 - 1.1e-16 60.2 0.7 1.1e-16 60.2 0.7 3.5 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF2267 PF10025.9 CEP18213.1 - 0.0087 16.3 0.5 0.022 15.0 0.4 1.7 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) DUF1207 PF06727.11 CEP18213.1 - 0.17 10.8 0.2 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) S1 PF00575.23 CEP18214.1 - 6.2e-47 157.8 24.5 4.2e-08 33.4 0.2 10.0 9 1 0 9 9 9 8 S1 RNA binding domain Suf PF05843.14 CEP18214.1 - 1.1e-10 42.0 1.2 1.1e-10 42.0 1.2 5.2 3 1 3 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CEP18214.1 - 5.3e-05 23.7 0.0 0.46 11.4 0.0 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CEP18214.1 - 0.00034 21.1 0.0 0.82 10.2 0.0 3.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18214.1 - 0.0034 17.4 0.2 0.043 13.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEP18214.1 - 0.016 14.5 0.1 0.19 10.9 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP18214.1 - 0.026 15.2 0.0 0.11 13.1 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP18214.1 - 0.037 14.3 0.2 0.23 11.8 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP18214.1 - 0.12 13.0 0.1 33 5.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RRN3 PF05327.11 CEP18214.1 - 1.9 6.9 12.8 5.3 5.5 12.8 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Metallophos PF00149.28 CEP18215.1 - 2.9e-12 47.5 1.4 2.9e-12 47.5 1.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WRKY PF03106.15 CEP18216.1 - 7.8e-11 42.0 3.6 2e-10 40.8 3.6 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.16 CEP18216.1 - 0.047 13.8 0.9 0.1 12.7 0.9 1.6 1 0 0 1 1 1 0 FLYWCH zinc finger domain CDC24_OB1 PF17246.2 CEP18216.1 - 0.15 12.2 3.0 3.8 7.7 0.1 2.9 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 1 DUF4097 PF13349.6 CEP18219.1 - 2e-08 33.9 4.9 3.4e-06 26.6 0.8 2.7 2 1 0 3 3 3 2 Putative adhesin 2-ph_phosp PF04029.14 CEP18219.1 - 1.9 7.6 6.5 0.32 10.2 0.5 2.1 1 1 1 2 2 2 0 2-phosphosulpholactate phosphatase bZIP_2 PF07716.15 CEP18220.1 - 2.5e-10 40.2 9.9 2.5e-10 40.2 9.9 1.9 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.9 CEP18220.1 - 0.0014 18.8 1.3 0.0033 17.6 1.3 1.6 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.21 CEP18220.1 - 0.0018 18.3 7.7 0.0045 17.1 7.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor WD40 PF00400.32 CEP18221.1 - 2.5e-54 180.0 27.3 6.7e-08 33.1 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 CEP18221.1 - 3.3e-13 49.3 0.4 6.7e-13 48.3 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CEP18221.1 - 4e-12 45.6 10.0 0.018 13.7 0.2 6.3 3 2 3 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CEP18221.1 - 5.5e-10 39.4 3.6 0.0089 16.3 0.1 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CEP18221.1 - 2.4e-09 36.9 0.2 5.7e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CEP18221.1 - 0.0031 16.9 0.1 0.52 9.6 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain F-box_4 PF15966.5 CEP18221.1 - 0.0078 16.1 0.8 0.067 13.1 0.0 2.7 3 0 0 3 3 3 1 F-box Nucleoporin_N PF08801.11 CEP18221.1 - 0.0089 14.8 0.6 3.7 6.2 0.0 3.5 3 1 1 4 4 4 1 Nup133 N terminal like BBS2_Mid PF14783.6 CEP18221.1 - 0.011 15.8 0.0 3.6 7.7 0.0 4.0 3 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 CEP18221.1 - 0.013 14.4 9.5 2 7.2 0.2 4.4 2 2 3 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CEP18221.1 - 0.4 9.6 6.2 2.1 7.2 0.1 3.7 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RVT_1 PF00078.27 CEP18222.1 - 2.4e-20 73.0 0.0 5.1e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CEP18222.1 - 0.0052 17.0 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 RNase H Macoilin PF09726.9 CEP18222.1 - 0.057 12.0 4.9 0.083 11.4 4.9 1.2 1 0 0 1 1 1 0 Macoilin family FUSC_2 PF13515.6 CEP18223.1 - 1.1e-17 64.3 12.5 1.1e-17 64.3 12.5 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 CEP18223.1 - 7.8e-14 51.2 5.4 7.8e-14 51.2 5.4 2.7 3 0 0 3 3 3 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 CEP18223.1 - 1.9e-13 50.8 1.0 1.9e-13 50.8 1.0 2.2 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CEP18223.1 - 5.6e-11 42.0 1.7 5.6e-11 42.0 1.7 3.8 2 1 0 2 2 2 1 Aluminium activated malate transporter Pkinase PF00069.25 CEP18224.1 - 5.2e-40 137.5 0.0 5.6e-26 91.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18224.1 - 8.7e-20 71.1 0.0 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_EZ PF13513.6 CEP18224.1 - 4.7e-18 65.3 2.8 7.9e-12 45.4 0.0 6.7 5 1 1 6 6 6 1 HEAT-like repeat HEAT PF02985.22 CEP18224.1 - 1.3e-15 56.1 13.5 0.00014 21.8 0.0 10.3 10 0 0 10 10 9 3 HEAT repeat IBN_N PF03810.19 CEP18224.1 - 2e-09 37.2 2.3 3.1e-09 36.6 0.7 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CEP18224.1 - 5.8e-09 36.2 2.8 0.0049 17.2 0.0 6.3 4 3 4 8 8 8 3 HEAT repeats Arm PF00514.23 CEP18224.1 - 2.7e-06 27.2 2.2 0.0067 16.4 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 CEP18224.1 - 5.5e-06 25.7 0.7 0.89 8.6 0.0 3.8 3 1 0 3 3 3 3 RNAPII transcription regulator C-terminal APH PF01636.23 CEP18224.1 - 5.6e-05 23.2 0.0 0.0013 18.7 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF3385 PF11865.8 CEP18224.1 - 0.00041 20.3 3.5 7.2 6.5 0.1 5.4 5 1 2 7 7 7 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 CEP18224.1 - 0.00059 19.5 2.0 1.8 8.1 0.3 4.2 4 0 0 4 4 4 2 CLASP N terminal Proteasom_PSMB PF10508.9 CEP18224.1 - 0.00092 17.8 2.1 0.65 8.4 0.1 3.1 2 2 1 3 3 3 2 Proteasome non-ATPase 26S subunit TIP120 PF08623.10 CEP18224.1 - 0.0012 18.7 4.3 0.1 12.4 0.0 4.1 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) Telomere_reg-2 PF10193.9 CEP18224.1 - 0.0052 17.2 5.6 0.97 9.9 0.1 4.8 3 1 2 5 5 5 1 Telomere length regulation protein Vac14_Fab1_bd PF12755.7 CEP18224.1 - 0.013 16.1 5.0 7.2 7.3 0.0 5.6 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 CEP18224.1 - 0.11 12.1 3.3 3.3 7.2 0.0 3.8 2 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II KAR9 PF08580.10 CEP18225.1 - 1.8e-19 69.8 21.3 4.9e-15 55.2 12.9 3.1 1 1 1 2 2 2 2 Yeast cortical protein KAR9 GAS2 PF02187.17 CEP18225.1 - 1.4e-05 25.0 0.2 7.3e-05 22.8 0.2 2.3 1 1 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain ALIX_LYPXL_bnd PF13949.6 CEP18225.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.7 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF1285 PF06938.11 CEP18225.1 - 0.11 12.5 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) CPSase_L_D2 PF02786.17 CEP18226.1 - 2.2e-80 269.1 0.3 3.9e-80 268.3 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CEP18226.1 - 1.5e-72 243.5 0.0 2.4e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CEP18226.1 - 2.2e-36 124.8 0.1 5e-36 123.6 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CEP18226.1 - 5.4e-31 106.9 0.0 3e-30 104.5 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CEP18226.1 - 1.2e-28 100.4 0.1 2.4e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CEP18226.1 - 1.6e-18 66.3 3.7 8.4e-18 64.0 1.5 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CEP18226.1 - 5.8e-14 51.7 0.7 2.8e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CEP18226.1 - 5.7e-11 42.3 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 CEP18226.1 - 2.6e-08 34.5 2.6 0.0062 17.2 0.3 3.4 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.22 CEP18226.1 - 6.8e-08 32.3 0.1 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CEP18226.1 - 1.9e-05 24.8 0.0 5.3e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CEP18226.1 - 0.00012 21.8 0.2 0.00044 19.9 0.2 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 CEP18226.1 - 0.00016 21.0 0.3 0.035 13.3 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 CEP18226.1 - 0.0002 21.0 0.1 0.0016 18.0 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CEP18226.1 - 0.0006 19.6 0.0 0.0032 17.3 0.0 2.3 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 CEP18226.1 - 0.0026 17.7 0.2 0.0092 15.9 0.2 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.19 CEP18226.1 - 0.0044 16.9 0.0 0.028 14.3 0.2 2.2 2 0 0 2 2 2 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 CEP18226.1 - 0.0057 15.9 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp NQRA PF05896.11 CEP18226.1 - 0.015 14.8 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF3182 PF11379.8 CEP18226.1 - 0.038 13.0 0.0 0.093 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) PNPase PF03726.14 CEP18226.1 - 0.13 12.8 0.3 0.49 10.9 0.3 2.0 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Peptidase_M23 PF01551.22 CEP18226.1 - 0.15 12.3 0.3 0.77 10.0 0.1 2.5 2 0 0 2 2 1 0 Peptidase family M23 DDE_3 PF13358.6 CEP18228.1 - 9.4e-18 64.4 1.6 6.6e-12 45.4 0.0 3.3 3 1 1 4 4 4 2 DDE superfamily endonuclease MSV199 PF10553.9 CEP18228.1 - 0.024 14.9 3.2 0.34 11.1 0.1 2.5 3 0 0 3 3 3 0 MSV199 domain IF-2B PF01008.17 CEP18229.1 - 1.1e-64 218.4 0.1 2.4e-64 217.3 0.1 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 CEP18229.1 - 0.074 13.0 0.7 1.5 8.8 0.0 2.9 3 1 1 4 4 4 0 DeoR C terminal sensor domain Imm49 PF15575.6 CEP18229.1 - 0.077 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 49 DUF4112 PF13430.6 CEP18230.1 - 1.8e-32 111.7 0.6 3.4e-32 110.9 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) TFIID_30kDa PF03540.13 CEP18230.1 - 3.6e-23 81.2 0.2 6.9e-23 80.3 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 CEP18230.1 - 0.028 14.4 0.6 2.1 8.4 0.1 3.0 2 1 0 2 2 2 0 Bromodomain associated SLX9 PF15341.6 CEP18230.1 - 0.075 13.4 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 WD40 PF00400.32 CEP18231.1 - 1e-13 51.5 6.4 0.019 15.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18231.1 - 1.3e-06 28.6 0.1 0.062 13.6 0.0 3.8 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CEP18231.1 - 0.0024 17.5 0.0 0.02 14.5 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain Pro_CA PF00484.19 CEP18232.1 - 6.6e-50 169.4 0.5 9.8e-50 168.9 0.5 1.3 1 0 0 1 1 1 1 Carbonic anhydrase zf-C2H2 PF00096.26 CEP18233.1 - 2.9e-22 77.8 22.8 5.5e-07 29.7 0.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP18233.1 - 9e-22 76.5 19.1 3e-06 27.4 1.8 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP18233.1 - 1.3e-11 44.2 20.8 0.0069 17.1 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 CEP18233.1 - 0.0011 19.5 5.4 0.24 12.1 0.1 3.7 3 1 1 4 4 4 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CEP18233.1 - 0.012 15.9 11.9 5.8 7.3 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CEP18233.1 - 0.027 14.2 0.4 0.027 14.2 0.4 3.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-met PF12874.7 CEP18233.1 - 0.03 14.7 7.6 36 4.9 0.2 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 CEP18233.1 - 0.033 14.9 15.0 0.046 14.4 2.8 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 CEP18233.1 - 0.21 11.9 12.3 0.29 11.5 1.3 3.3 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 CEP18233.1 - 0.76 9.9 9.3 4.2 7.5 0.2 3.8 2 2 1 3 3 3 0 Aberrant zinc-finger Aha1_N PF09229.11 CEP18235.1 - 1.1e-38 132.6 1.7 1.6e-38 132.0 1.7 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CEP18235.1 - 9.8e-20 71.0 0.5 1.7e-19 70.3 0.5 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LTXXQ PF07813.12 CEP18235.1 - 0.045 14.5 0.1 0.086 13.6 0.1 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein Folliculin PF11704.8 CEP18236.1 - 1.9e-38 132.2 1.3 2.5e-38 131.8 0.0 1.8 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pyrid_oxidase_2 PF13883.6 CEP18236.1 - 2.2e-31 109.1 0.0 4.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RITA PF17066.5 CEP18236.1 - 0.067 12.8 5.1 0.17 11.4 5.1 1.7 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein FSA_C PF10479.9 CEP18236.1 - 0.24 9.5 9.6 0.35 8.9 9.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ribosomal_S26e PF01283.19 CEP18237.1 - 8.6e-54 180.6 9.2 9.4e-54 180.4 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CEP18237.1 - 0.16 12.6 3.3 1.1 10.0 2.2 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_hydro_38N PF01074.22 CEP18238.1 - 3.6e-86 289.1 0.3 8.4e-86 287.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CEP18238.1 - 1e-59 202.2 0.2 1.7e-59 201.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CEP18238.1 - 3.3e-13 49.6 0.0 1.1e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain zf-C2H2 PF00096.26 CEP18238.1 - 4e-13 49.0 5.7 1.2e-05 25.4 1.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro38C2 PF17677.1 CEP18238.1 - 2e-10 40.6 0.1 4.4e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain zf-H2C2_2 PF13465.6 CEP18238.1 - 2e-08 34.3 13.4 3.7e-05 24.0 0.6 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP18238.1 - 5.4e-08 33.0 5.4 0.0016 19.1 1.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CEP18238.1 - 0.00063 20.0 0.4 0.0014 18.9 0.4 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CEP18238.1 - 0.0011 18.6 2.6 0.054 13.3 0.2 2.7 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CEP18238.1 - 0.011 16.0 0.6 0.099 13.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CEP18238.1 - 0.021 14.8 4.5 0.36 10.9 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 CEP18238.1 - 0.11 12.4 2.5 0.67 9.9 0.7 2.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 CEP18238.1 - 0.31 11.5 2.6 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GTP_EFTU PF00009.27 CEP18239.1 - 1.4e-21 77.0 0.0 2.9e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CEP18239.1 - 2.2e-08 34.4 0.7 6e-08 33.0 0.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CEP18239.1 - 0.00099 19.4 2.5 0.0013 19.0 0.7 2.2 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CEP18239.1 - 0.0079 16.3 0.2 0.031 14.4 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CEP18239.1 - 0.033 13.7 0.2 2.4 7.6 0.0 2.8 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_M17 PF00883.21 CEP18240.1 - 9e-62 209.1 0.0 1.1e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Abhydrolase_1 PF00561.20 CEP18241.1 - 5.2e-07 29.6 0.2 4.8e-06 26.4 0.2 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CEP18241.1 - 4.5e-05 23.3 0.1 7.9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CEP18241.1 - 0.00022 21.2 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CEP18241.1 - 0.0032 17.0 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 CEP18241.1 - 0.0072 15.7 0.0 0.083 12.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 CEP18241.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CEP18241.1 - 0.035 14.7 0.2 0.07 13.7 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family SET PF00856.28 CEP18242.1 - 8.4e-06 26.3 0.0 2.6e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 SET domain Rhodanese_C PF12368.8 CEP18242.1 - 0.57 10.6 12.7 0.42 11.0 6.0 2.6 2 0 0 2 2 2 0 Rhodanase C-terminal zf-MYND PF01753.18 CEP18242.1 - 0.79 9.9 26.2 0.2 11.8 16.6 2.5 2 0 0 2 2 2 0 MYND finger Sharpin_PH PF16764.5 CEP18243.1 - 0.029 14.1 0.1 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Sharpin PH domain F-box-like PF12937.7 CEP18243.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.9 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 CEP18243.1 - 0.53 10.5 10.5 2.3 8.5 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich repeat DUF2436 PF10365.9 CEP18243.1 - 2.2 8.0 5.7 0.24 11.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2436) HTH_23 PF13384.6 CEP18247.1 - 0.00031 20.5 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP18247.1 - 0.00073 19.5 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 CEP18247.1 - 0.0039 17.3 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 CEP18247.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.16 CEP18247.1 - 0.0073 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_1 PF00126.27 CEP18247.1 - 0.023 14.7 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family UPF0175 PF03683.13 CEP18247.1 - 0.032 14.0 0.3 0.8 9.5 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) CENP-B_N PF04218.13 CEP18247.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_40 PF14493.6 CEP18247.1 - 0.054 13.9 0.1 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 CEP18247.1 - 0.065 13.0 0.2 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 CEP18247.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_17 PF12728.7 CEP18247.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.19 CEP18247.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MarR PF01047.22 CEP18247.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 MarR family SpoIIID PF12116.8 CEP18247.1 - 0.17 12.0 0.6 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_24 PF13412.6 CEP18247.1 - 0.18 11.4 0.4 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MerR_1 PF13411.6 CEP18247.1 - 0.43 10.7 2.2 0.89 9.7 0.0 2.7 3 0 0 3 3 3 0 MerR HTH family regulatory protein Aldo_ket_red PF00248.21 CEP18248.1 - 1.8e-43 148.8 0.1 2.3e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Arf PF00025.21 CEP18249.1 - 2.2e-76 255.2 0.1 3.2e-76 254.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP18249.1 - 4e-15 56.1 0.0 7.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP18249.1 - 2e-13 50.3 0.0 3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CEP18249.1 - 1.3e-12 47.6 0.3 3.8e-08 32.9 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEP18249.1 - 3.8e-11 42.7 0.0 6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEP18249.1 - 9.5e-10 38.2 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP18249.1 - 7.6e-06 26.0 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP18249.1 - 5.4e-05 22.8 0.1 0.00036 20.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CEP18249.1 - 0.019 15.5 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CEP18249.1 - 0.039 14.5 0.6 0.23 12.0 0.6 2.0 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 CEP18249.1 - 0.059 12.4 0.2 1.4 7.9 0.1 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CEP18249.1 - 0.063 12.9 0.4 8 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 CEP18250.1 - 1.3e-32 111.3 12.9 5.1e-07 30.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18250.1 - 5.6e-08 33.0 0.6 0.018 15.3 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 CEP18250.1 - 0.0018 18.4 0.0 0.52 10.6 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1921) Methyltransf_25 PF13649.6 CEP18251.1 - 2e-12 47.6 0.0 7.1e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP18251.1 - 3.1e-11 43.8 0.0 7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP18251.1 - 7.1e-08 32.5 0.0 1.6e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18251.1 - 7.9e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP18251.1 - 0.00089 20.0 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP18251.1 - 0.025 14.0 0.0 0.069 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 CEP18251.1 - 0.04 13.2 0.0 0.15 11.4 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family BLOC1_2 PF10046.9 CEP18252.1 - 0.019 15.2 0.9 0.043 14.1 0.4 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPE65 PF03055.15 CEP18253.1 - 5e-96 322.7 0.0 5.9e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AIP3 PF03915.13 CEP18254.1 - 1.8e-86 290.8 38.0 1.8e-86 290.8 38.0 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Scaffolding_pro PF11418.8 CEP18254.1 - 0.12 12.9 15.5 2.2 8.9 0.7 5.3 4 2 2 6 6 6 0 Phi29 scaffolding protein RPW8 PF05659.11 CEP18254.1 - 5 6.8 17.6 0.016 14.9 4.5 3.0 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AKNA PF12443.8 CEP18254.1 - 5.4 7.7 10.4 1.5 9.5 2.9 4.0 2 1 2 4 4 4 0 AT-hook-containing transcription factor MG2 PF01835.19 CEP18255.1 - 0.014 15.8 0.0 0.02 15.4 0.0 1.2 1 0 0 1 1 1 0 MG2 domain DUF4945 PF16303.5 CEP18255.1 - 0.028 14.3 0.0 2.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4945) Glyco_hydro_61 PF03443.14 CEP18255.1 - 0.058 13.3 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 APG9 PF04109.16 CEP18256.1 - 5.3e-184 612.7 13.5 8.9e-177 588.9 7.5 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 DUF1770 PF08589.10 CEP18256.1 - 3.6 8.6 6.7 1.5 9.8 2.9 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Aldedh PF00171.22 CEP18257.1 - 1.2e-97 327.4 0.0 1.4e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CEP18257.1 - 0.079 12.9 0.2 0.23 11.4 0.2 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Inv-AAD PF18785.1 CEP18258.1 - 4.4e-26 91.2 1.3 2.3e-25 89.0 1.3 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 CEP18258.1 - 3.2e-21 75.1 0.2 3.9e-21 74.8 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CEP18258.1 - 2.6e-10 40.2 0.0 3.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 CEP18258.1 - 7.8e-05 22.6 0.0 0.00063 19.7 0.0 2.0 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Indigoidine_A PF04227.12 CEP18258.1 - 0.054 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein APOBEC3 PF18771.1 CEP18258.1 - 0.076 13.1 0.0 0.19 11.9 0.0 1.7 1 1 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 CEP18258.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Cyclin PF08613.11 CEP18259.1 - 9.6e-12 45.6 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP18259.1 - 1.1e-06 28.4 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4536 PF15055.6 CEP18259.1 - 0.011 15.9 0.3 0.88 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Cue1_U7BR PF18499.1 CEP18259.1 - 0.072 13.1 2.4 7.7 6.6 0.1 3.0 3 0 0 3 3 3 0 Ubc7p-binding region of Cue1 RNAse_A_bac PF18431.1 CEP18259.1 - 0.16 13.0 0.0 0.32 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain SWI-SNF_Ssr4 PF08549.10 CEP18260.1 - 3e-11 42.7 5.0 3e-11 42.7 5.0 2.3 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1750) LMBR1 PF04791.16 CEP18260.1 - 0.0072 15.3 9.6 0.012 14.6 9.6 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Med15 PF09606.10 CEP18260.1 - 0.99 8.0 46.9 0.72 8.5 26.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Velvet PF11754.8 CEP18260.1 - 2 8.3 23.3 1.1 9.1 12.8 2.3 2 0 0 2 2 2 0 Velvet factor PepSY_TM PF03929.16 CEP18260.1 - 5 6.7 8.7 12 5.4 4.6 2.2 2 0 0 2 2 2 0 PepSY-associated TM region Proteasome PF00227.26 CEP18261.1 - 2.6e-47 160.8 0.0 3.3e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP18261.1 - 2.1e-13 49.6 0.1 3.6e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HATPase_c PF02518.26 CEP18262.1 - 6e-28 97.6 0.0 6e-27 94.4 0.0 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CEP18262.1 - 2.2e-25 89.0 0.5 1.6e-22 79.8 0.5 2.7 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CEP18262.1 - 9.6e-17 60.8 1.7 2.7e-16 59.4 1.7 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 CEP18262.1 - 0.046 13.6 1.1 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NDK PF00334.19 CEP18263.1 - 2e-32 112.1 0.0 4.9e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Nucleoside diphosphate kinase AMP-binding PF00501.28 CEP18264.1 - 3.5e-101 338.9 0.0 4.5e-101 338.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAR1 PF03101.15 CEP18266.1 - 0.00035 21.2 2.0 0.00035 21.2 2.0 2.8 2 1 0 2 2 2 1 FAR1 DNA-binding domain MBOAT_2 PF13813.6 CEP18267.1 - 1.8e-07 31.3 1.4 1.8e-07 31.3 1.4 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WASH-7_C PF14746.6 CEP18267.1 - 0.023 14.4 0.3 0.039 13.6 0.3 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MFS_1 PF07690.16 CEP18268.1 - 8.1e-36 123.7 35.2 9.9e-36 123.4 34.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP18268.1 - 1.1e-35 123.4 30.0 2e-33 116.0 28.5 3.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 CEP18268.1 - 0.00056 18.9 12.1 0.014 14.3 12.1 2.3 1 1 0 1 1 1 1 MFS_1 like family Ta0938 PF11494.8 CEP18268.1 - 0.061 13.6 0.5 0.17 12.2 0.5 1.7 1 0 0 1 1 1 0 Ta0938 UPF0122 PF04297.14 CEP18268.1 - 0.082 13.2 0.0 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like ATG22 PF11700.8 CEP18268.1 - 0.32 9.6 19.7 0.19 10.3 11.6 2.2 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like RNA_pol_Rpb6 PF01192.22 CEP18269.1 - 2.3e-16 59.5 0.2 3.2e-16 59.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 CEP18269.1 - 0.013 15.3 0.1 0.014 15.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Ceramidase_alk PF04734.13 CEP18270.1 - 4.4e-201 668.9 0.3 5.3e-201 668.7 0.3 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CEP18270.1 - 2e-40 138.4 0.4 3e-40 137.8 0.4 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal MR_MLE_C PF13378.6 CEP18271.1 - 2.9e-55 187.2 0.0 4.4e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CEP18271.1 - 0.00026 21.2 0.0 0.00057 20.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Hus1 PF04005.12 CEP18272.1 - 1.8e-48 165.1 0.0 2.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein DUF3336 PF11815.8 CEP18273.1 - 4.5e-32 110.6 0.8 8.4e-32 109.8 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CEP18273.1 - 9.6e-20 71.6 0.0 2.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Glyco_transf_49 PF13896.6 CEP18274.1 - 2.5e-57 194.7 2.4 4e-47 161.2 1.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 CEP18274.1 - 0.00084 19.8 0.5 0.0022 18.5 0.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Pkinase PF00069.25 CEP18275.1 - 3.8e-69 233.0 0.0 5e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18275.1 - 6.7e-33 114.1 0.0 1.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP18275.1 - 0.00083 18.8 1.4 0.0016 17.9 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP18275.1 - 0.00099 18.1 2.8 0.001 18.1 0.1 2.2 2 1 1 3 3 3 1 Haspin like kinase domain APH PF01636.23 CEP18275.1 - 0.022 14.7 0.2 0.11 12.4 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MTP18 PF10558.9 CEP18276.1 - 9.2e-63 211.3 5.0 3.4e-31 108.5 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) PTPA PF03095.15 CEP18277.1 - 1e-120 402.8 0.3 1.2e-120 402.6 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Urb2 PF10441.9 CEP18278.1 - 5.8e-43 147.2 2.6 5.8e-43 147.2 2.6 3.8 5 0 0 5 5 5 1 Urb2/Npa2 family SapB_1 PF05184.15 CEP18278.1 - 0.039 14.0 1.2 2.2 8.4 0.4 3.4 2 0 0 2 2 2 0 Saposin-like type B, region 1 NAD_binding_5 PF07994.12 CEP18278.1 - 0.11 11.9 11.5 0.67 9.3 3.7 3.2 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase Dynein_AAA_lid PF17852.1 CEP18278.1 - 0.5 10.4 10.2 5.7 7.0 0.0 6.2 6 0 0 6 6 6 0 Dynein heavy chain AAA lid domain C2 PF00168.30 CEP18279.1 - 1e-87 289.1 9.2 5.8e-20 71.5 0.0 6.4 6 0 0 6 6 6 6 C2 domain Anillin_N PF16018.5 CEP18280.1 - 0.0099 16.5 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 1 Anillin N-terminus Ras PF00071.22 CEP18281.1 - 1.3e-62 210.2 0.2 1.7e-62 209.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18281.1 - 1.4e-35 122.1 0.8 2.5e-35 121.3 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP18281.1 - 2.9e-13 49.7 0.1 4.6e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP18281.1 - 2.3e-07 30.9 0.1 4.4e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP18281.1 - 0.00018 21.5 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CEP18281.1 - 0.00096 18.7 0.3 0.0047 16.5 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CEP18281.1 - 0.0012 19.1 0.1 0.012 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 CEP18281.1 - 0.0017 17.8 0.1 0.0024 17.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CEP18281.1 - 0.002 17.6 0.0 0.0045 16.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DLIC PF05783.11 CEP18281.1 - 0.0046 15.8 0.1 0.019 13.8 0.1 1.8 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CEP18281.1 - 0.0058 17.0 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CEP18281.1 - 0.0079 15.9 0.1 0.016 14.9 0.0 1.6 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CEP18281.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CEP18281.1 - 0.029 13.8 0.0 0.085 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 CEP18281.1 - 0.029 13.9 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 CEP18281.1 - 0.041 13.9 0.1 0.13 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CEP18281.1 - 0.045 13.5 0.9 0.16 11.8 0.7 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CEP18281.1 - 0.048 14.2 0.2 0.066 13.7 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CEP18281.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 CEP18281.1 - 0.069 13.1 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF3533 PF12051.8 CEP18281.1 - 0.12 11.2 0.7 0.14 11.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_5 PF07728.14 CEP18281.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_L3 PF00297.22 CEP18283.1 - 2.5e-184 612.5 11.2 2.8e-184 612.3 11.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Polysacc_lyase PF14099.6 CEP18284.1 - 0.0087 15.9 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase DUF1800 PF08811.11 CEP18285.1 - 0.062 12.3 0.2 0.13 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Myb_DNA-binding PF00249.31 CEP18286.1 - 1.6e-51 172.2 17.5 1.1e-13 51.1 0.4 6.1 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP18286.1 - 1.4e-38 130.9 18.6 7.4e-16 58.2 0.9 6.4 3 2 3 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.10 CEP18286.1 - 1.5e-07 31.4 12.4 0.051 13.6 0.0 6.1 2 1 4 6 6 6 3 SLIDE Myb_DNA-bind_7 PF15963.5 CEP18286.1 - 1e-05 25.4 17.2 0.0002 21.2 2.5 5.0 4 1 1 5 5 5 3 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CEP18286.1 - 0.002 18.3 9.2 0.25 11.5 0.0 4.5 3 1 2 5 5 5 2 SANT/Myb-like domain of DAMP1 BUD22 PF09073.10 CEP18287.1 - 1.9e-31 109.9 58.9 1.4e-18 67.5 18.7 2.3 1 1 1 2 2 2 2 BUD22 CTP_transf_like PF01467.26 CEP18288.1 - 7.8e-47 159.1 0.0 9.1e-28 97.2 0.0 2.4 2 1 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CEP18288.1 - 0.00058 19.8 3.1 0.83 9.5 0.3 3.2 3 1 0 3 3 3 2 FAD synthetase Pantoate_ligase PF02569.15 CEP18288.1 - 0.036 13.3 0.1 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase ScdA_N PF04405.14 CEP18288.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) GPI-anchored PF10342.9 CEP18290.1 - 1.9e-09 38.2 0.3 1.9e-09 38.2 0.3 3.2 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Thioredoxin PF00085.20 CEP18291.1 - 2.4e-65 217.0 1.4 4.1e-35 119.9 0.1 4.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CEP18291.1 - 5.1e-42 143.9 3.8 2e-29 102.9 1.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CEP18291.1 - 9e-08 32.4 0.4 0.027 14.8 0.0 5.0 4 2 2 6 6 6 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CEP18291.1 - 2.4e-07 30.9 0.1 0.019 15.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CEP18291.1 - 2.7e-07 30.2 0.0 0.0055 16.1 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CEP18291.1 - 3.4e-07 30.7 2.4 0.012 16.1 0.2 4.1 3 3 0 3 3 3 2 Thioredoxin-like domain ERp29_N PF07912.13 CEP18291.1 - 1.1e-06 28.8 0.3 0.27 11.4 0.0 4.0 4 0 0 4 4 4 2 ERp29, N-terminal domain Calsequestrin PF01216.17 CEP18291.1 - 0.00018 20.7 5.5 0.0007 18.7 1.6 2.6 3 0 0 3 3 3 1 Calsequestrin Thioredoxin_9 PF14595.6 CEP18291.1 - 0.0032 17.2 0.2 0.71 9.7 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 CEP18291.1 - 0.0077 16.3 0.2 0.83 9.7 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin domain DUF836 PF05768.14 CEP18291.1 - 0.09 13.2 0.1 0.37 11.2 0.1 2.1 2 0 0 2 2 1 0 Glutaredoxin-like domain (DUF836) NIBRIN_BRCT_II PF16508.5 CEP18291.1 - 0.1 12.9 0.2 1.3 9.4 0.0 2.5 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein DSBA PF01323.20 CEP18291.1 - 0.11 12.3 1.0 11 5.7 0.0 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain CorA PF01544.18 CEP18292.1 - 4.2e-46 157.6 4.7 8.3e-46 156.6 4.7 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein BBP1_N PF15271.6 CEP18292.1 - 0.15 12.8 0.0 0.15 12.8 0.0 3.0 1 1 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein GFO_IDH_MocA PF01408.22 CEP18293.1 - 4.1e-26 92.2 0.3 7.1e-26 91.4 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 CEP18293.1 - 5.7e-09 36.4 0.1 1.1e-08 35.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CEP18293.1 - 5.1e-06 26.6 0.0 8.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 CEP18293.1 - 6.8e-06 26.7 0.0 1.3e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CEP18293.1 - 0.00036 21.0 0.1 0.00062 20.2 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEP18293.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CEP18293.1 - 0.03 13.9 0.2 0.072 12.7 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF613 PF04764.12 CEP18293.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF613) BTG PF07742.12 CEP18294.1 - 1.3e-35 121.7 0.0 1.7e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 BTG family ECH_1 PF00378.20 CEP18295.1 - 1.1e-51 175.6 0.0 1.5e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CEP18295.1 - 2.1e-31 109.6 0.1 3.3e-31 109.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 CEP18295.1 - 0.01 16.1 0.9 0.02 15.2 0.9 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Peptidase_S49 PF01343.18 CEP18295.1 - 0.14 12.1 0.4 5.3 7.0 0.1 2.4 1 1 1 2 2 2 0 Peptidase family S49 Peptidase_M3 PF01432.20 CEP18296.1 - 1.5e-140 469.5 1.9 2.3e-140 468.9 1.9 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF3201 PF11447.8 CEP18296.1 - 0.027 14.0 2.8 6.4 6.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3201) TMEM52 PF14979.6 CEP18296.1 - 0.15 12.0 0.5 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane 52 Peptidase_C1_2 PF03051.15 CEP18297.1 - 6.9e-165 549.1 0.3 8.3e-165 548.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CEP18297.1 - 5.5e-05 23.3 0.1 0.095 12.8 0.2 2.6 2 0 0 2 2 2 2 Papain family cysteine protease THEG4 PF15834.5 CEP18297.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Testis highly expressed protein 4 GFO_IDH_MocA PF01408.22 CEP18298.1 - 2.1e-25 89.9 0.0 3.6e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CEP18298.1 - 4.7e-15 55.6 0.0 8.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CEP18298.1 - 0.00016 22.3 0.0 0.00032 21.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 CEP18298.1 - 0.0023 18.6 0.0 0.0054 17.4 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Semialdhyde_dh PF01118.24 CEP18298.1 - 0.003 18.0 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.32 CEP18299.1 - 2.9e-19 69.0 10.7 7.3e-06 26.6 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18299.1 - 1.1e-09 38.5 0.0 4.3e-05 23.7 0.0 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP18299.1 - 0.00017 21.1 0.0 0.00062 19.2 0.0 1.8 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 CEP18299.1 - 0.0057 16.6 0.1 0.087 12.7 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP18299.1 - 0.056 12.4 0.7 15 4.4 0.0 3.1 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HIG_1_N PF04588.13 CEP18300.1 - 2.4e-18 66.1 1.9 2.4e-18 66.1 1.9 1.9 3 0 0 3 3 3 1 Hypoxia induced protein conserved region DUF5423 PF17461.2 CEP18300.1 - 0.046 12.6 0.1 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Mntp PF02659.15 CEP18300.1 - 0.073 12.8 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative manganese efflux pump MaoC_dehydratas PF01575.19 CEP18301.1 - 8.5e-29 99.6 0.0 1.4e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CEP18301.1 - 6.8e-07 29.5 0.0 3.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF4743 PF15916.5 CEP18302.1 - 2e-18 66.5 0.0 2.9e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CEP18302.1 - 1.7e-07 31.3 0.0 3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Arrestin_N PF00339.29 CEP18303.1 - 2.9e-10 40.4 0.0 5.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TMEM171 PF15471.6 CEP18303.1 - 5.1 6.0 6.2 8.6 5.2 6.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Homeodomain PF00046.29 CEP18304.1 - 1.5e-21 75.9 1.0 3.5e-21 74.8 1.0 1.7 1 0 0 1 1 1 1 Homeodomain HERV-K_REC PF15695.5 CEP18304.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Homeobox_KN PF05920.11 CEP18304.1 - 0.027 14.3 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF2597 PF10772.9 CEP18304.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) MFS_1_like PF12832.7 CEP18305.1 - 2.2e-61 207.9 18.1 2.7e-61 207.6 18.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CEP18305.1 - 4.3e-20 71.9 41.9 1.3e-11 44.1 22.3 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CEP18305.1 - 1.3e-07 31.0 9.3 1.3e-07 31.0 9.3 2.2 2 0 0 2 2 2 1 Nucleoside H+ symporter LacY_symp PF01306.19 CEP18305.1 - 5.6e-05 22.1 11.0 5.6e-05 22.1 11.0 2.9 2 1 0 2 2 2 1 LacY proton/sugar symporter PNTB_4TM PF12769.7 CEP18305.1 - 0.013 15.9 2.2 0.013 15.9 2.2 3.2 4 0 0 4 4 4 0 4TM region of pyridine nucleotide transhydrogenase, mitoch TPR_19 PF14559.6 CEP18307.1 - 1.2e-17 64.1 43.0 0.00063 20.2 1.8 8.7 5 2 3 9 9 9 7 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEP18307.1 - 2.7e-16 59.6 3.0 2.7e-16 59.6 3.0 3.6 3 1 1 4 4 4 1 Putative TPR-like repeat SRP72 PF08492.12 CEP18307.1 - 2e-14 53.7 4.4 2e-14 53.7 4.4 3.1 3 0 0 3 3 1 1 SRP72 RNA-binding domain TPR_14 PF13428.6 CEP18307.1 - 4.8e-13 48.7 25.5 0.11 13.3 0.1 10.9 8 3 4 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18307.1 - 2.2e-12 46.1 23.5 0.011 15.8 0.1 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 CEP18307.1 - 7.6e-12 45.7 26.9 0.00067 20.3 1.1 8.2 5 3 2 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CEP18307.1 - 1.4e-11 44.2 28.7 0.048 14.3 0.3 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP18307.1 - 2.9e-11 43.4 34.4 0.00051 20.2 0.4 7.6 2 2 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CEP18307.1 - 3.7e-11 42.3 18.2 0.11 12.8 0.0 7.4 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CEP18307.1 - 1.4e-08 34.9 22.1 0.00044 20.5 2.4 7.3 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP18307.1 - 1.3e-06 28.5 0.1 5.1 8.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CEP18307.1 - 1.8e-06 27.5 14.4 0.63 10.2 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP18307.1 - 1.7e-05 24.9 12.2 9.7 6.8 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEP18307.1 - 2.6e-05 24.3 11.2 4.1 7.6 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP18307.1 - 3.7e-05 23.2 20.3 0.0041 16.5 0.5 3.9 2 1 1 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 CEP18307.1 - 7.2e-05 22.4 20.6 0.79 9.6 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP18307.1 - 0.00087 18.9 19.4 0.075 12.7 1.0 6.6 7 0 0 7 7 7 2 TPR repeat BTAD PF03704.17 CEP18307.1 - 0.0065 16.9 12.8 0.012 16.1 0.1 5.3 4 2 0 5 5 5 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 CEP18307.1 - 0.011 15.6 13.8 0.66 9.9 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 CEP18307.1 - 0.017 15.3 0.0 80 3.8 0.0 4.6 5 0 0 5 5 4 0 PPR repeat ThiD2 PF17792.1 CEP18307.1 - 0.045 14.2 1.5 0.1 13.1 0.7 2.0 1 1 0 1 1 1 0 ThiD2 family TPR_3 PF07720.12 CEP18307.1 - 0.083 12.9 9.5 3 7.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Formyl_trans_N PF00551.19 CEP18308.1 - 2e-51 174.3 0.1 2.6e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1640 PF07798.11 CEP18311.1 - 3.5e-42 144.4 10.1 4.7e-42 144.0 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) APG5 PF04106.12 CEP18311.1 - 0.026 14.1 0.3 0.026 14.1 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg5 MIP-T3_C PF17749.1 CEP18311.1 - 0.066 13.2 13.2 0.21 11.6 13.1 2.1 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF740 PF05340.12 CEP18311.1 - 0.21 10.3 8.5 0.13 11.0 6.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF740) Chordopox_G3 PF06129.12 CEP18311.1 - 0.58 10.9 4.8 0.29 11.8 2.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus G3 protein 5_nucleotid PF05761.14 CEP18311.1 - 1.1 8.1 8.9 0.73 8.7 7.5 1.4 1 1 0 1 1 1 0 5' nucleotidase family Gtr1_RagA PF04670.12 CEP18312.1 - 2.3e-103 344.5 0.3 2.9e-103 344.2 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CEP18312.1 - 3e-09 36.6 0.1 5.7e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP18312.1 - 3.5e-09 36.9 0.1 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP18312.1 - 3.2e-08 33.3 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CEP18312.1 - 4.1e-07 30.1 0.0 7.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP18312.1 - 0.00037 20.1 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP18312.1 - 0.0014 18.5 0.3 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 CEP18312.1 - 0.004 17.7 0.3 0.0071 16.9 0.3 1.7 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.10 CEP18312.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF815 PF05673.13 CEP18312.1 - 0.03 13.5 0.4 0.099 11.8 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CEP18312.1 - 0.042 13.6 0.3 0.24 11.1 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CEP18312.1 - 0.16 11.7 0.4 0.37 10.6 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CEP18312.1 - 0.39 9.8 5.2 7 5.7 0.9 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Ribosomal_S18 PF01084.20 CEP18313.1 - 1.3e-22 79.7 0.1 2.5e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 GDI PF00996.18 CEP18314.1 - 2.1e-202 672.4 0.5 2.4e-202 672.2 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 CEP18314.1 - 5.8e-05 22.6 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF4351 PF14261.6 CEP18314.1 - 0.0089 16.1 0.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4351) IMS PF00817.20 CEP18316.1 - 7.4e-39 133.1 0.1 1.8e-38 131.9 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 CEP18316.1 - 1.3e-15 57.5 0.2 4.1e-15 55.9 0.1 2.0 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 CEP18316.1 - 1.7e-15 57.8 0.0 6.7e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 CEP18316.1 - 4.7e-08 33.3 0.1 1.6e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 CEP18316.1 - 1.6e-05 24.9 0.0 8.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 CEP18316.1 - 0.0017 18.6 0.0 0.0073 16.6 0.0 2.1 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Cdd1 PF11731.8 CEP18316.1 - 0.0049 17.1 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus BRCT PF00533.26 CEP18316.1 - 0.012 15.9 0.1 0.037 14.4 0.1 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1374 PF07118.11 CEP18316.1 - 0.076 13.5 1.0 0.24 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) Pox_A11 PF05061.13 CEP18316.1 - 0.1 11.8 0.1 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF1805 PF08827.11 CEP18316.1 - 0.18 12.2 0.0 1.2 9.5 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF1805) STIMATE PF12400.8 CEP18317.1 - 2.7e-41 141.0 10.5 4.8e-41 140.2 10.5 1.4 1 0 0 1 1 1 1 STIMATE family HECT_2 PF09814.9 CEP18318.1 - 0.11 11.4 1.8 0.16 10.8 1.8 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RNA_pol_Rpc34 PF05158.12 CEP18320.1 - 4.2e-86 289.4 0.0 5.5e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CEP18320.1 - 0.0067 16.6 0.3 0.059 13.5 0.1 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RPA_C PF08784.11 CEP18320.1 - 0.061 14.0 0.5 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 Replication protein A C terminal IgG_binding_B PF01378.17 CEP18320.1 - 0.32 11.1 2.3 0.51 10.4 0.1 2.5 3 1 0 3 3 3 0 B domain dCache_3 PF14827.6 CEP18322.1 - 0.026 14.2 0.4 0.026 14.2 0.4 1.8 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase Mcl1_mid PF12341.8 CEP18323.1 - 5.6e-90 301.7 0.0 3.4e-88 295.8 0.0 2.8 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CEP18323.1 - 1.9e-24 85.4 5.7 2.7e-05 24.8 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18323.1 - 1.2e-13 51.1 0.1 0.0008 19.7 0.0 5.8 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CEP18323.1 - 0.0023 17.3 1.3 0.004 16.5 0.2 1.9 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CEP18323.1 - 0.013 14.4 0.2 5.2 5.9 0.0 3.6 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CEP18323.1 - 0.071 13.2 0.1 0.32 11.1 0.1 2.1 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40_3 PF15911.5 CEP18323.1 - 0.097 12.7 1.5 4.8 7.3 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat DDE_3 PF13358.6 CEP18324.1 - 2.4e-13 50.1 0.0 1.2e-05 25.1 0.0 2.7 3 0 0 3 3 3 2 DDE superfamily endonuclease DUF1804 PF08822.11 CEP18324.1 - 0.049 13.6 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_23 PF13384.6 CEP18324.1 - 0.097 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 CEP18324.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix SWIM PF04434.17 CEP18328.1 - 0.013 15.2 2.1 0.027 14.1 2.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger PNP_UDP_1 PF01048.20 CEP18329.1 - 1.5e-42 145.5 2.4 2.6e-42 144.7 2.4 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily p450 PF00067.22 CEP18330.1 - 6.1e-81 272.5 0.0 7.6e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHO_dh PF01180.21 CEP18331.1 - 4.6e-63 213.2 0.0 5.3e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Beach PF02138.18 CEP18332.1 - 2.4e-38 132.1 0.0 4.9e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CEP18332.1 - 2.6e-09 37.5 11.5 0.002 18.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18332.1 - 2.9e-07 30.7 0.1 0.0045 17.3 0.0 5.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CEP18332.1 - 1.5e-06 27.7 0.0 5.7e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CEP18332.1 - 0.00037 19.9 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1722 PF08349.11 CEP18332.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Pkinase_Tyr PF07714.17 CEP18332.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Methyltransf_12 PF08242.12 CEP18336.1 - 3.3e-30 104.7 0.0 4.9e-15 56.1 0.0 3.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEP18336.1 - 8.2e-27 94.0 0.0 1.2e-15 57.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CEP18336.1 - 2.8e-23 82.4 0.0 9.5e-13 48.7 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CEP18336.1 - 5.2e-20 71.9 0.0 1.6e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18336.1 - 4.7e-14 52.4 0.0 3.9e-08 33.2 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CEP18336.1 - 8.7e-08 31.7 0.0 0.44 9.7 0.1 3.3 2 1 1 3 3 3 3 NNMT/PNMT/TEMT family MTS PF05175.14 CEP18336.1 - 1.1e-06 28.4 0.0 0.0009 18.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain DUF3419 PF11899.8 CEP18336.1 - 1.8e-06 27.4 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3419) CMAS PF02353.20 CEP18336.1 - 3.1e-05 23.4 0.0 0.019 14.3 0.0 2.4 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase CheR PF01739.18 CEP18336.1 - 6.3e-05 22.5 0.0 3.7 7.0 0.0 3.6 3 0 0 3 3 3 2 CheR methyltransferase, SAM binding domain NodS PF05401.11 CEP18336.1 - 6.5e-05 22.6 0.0 0.14 11.7 0.0 2.5 2 1 0 2 2 2 2 Nodulation protein S (NodS) PrmA PF06325.13 CEP18336.1 - 8.8e-05 22.0 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) DUF3298 PF11738.8 CEP18336.1 - 0.00024 22.1 10.5 0.21 12.6 0.0 4.0 3 1 1 4 4 4 2 Protein of unknown function (DUF3298) Methyltransf_24 PF13578.6 CEP18336.1 - 0.00036 21.5 0.0 0.34 11.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 CEP18336.1 - 0.00043 19.8 0.2 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 Tellurite resistance protein TehB POR PF01558.18 CEP18336.1 - 0.00081 19.5 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TylF PF05711.11 CEP18336.1 - 0.0063 15.8 0.1 3.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) Rsm22 PF09243.10 CEP18336.1 - 0.03 13.6 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_4 PF02390.17 CEP18336.1 - 0.035 13.6 0.0 0.41 10.1 0.0 2.9 2 1 1 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 CEP18336.1 - 0.14 11.5 0.0 17 4.6 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase domain PMT_4TMC PF16192.5 CEP18337.1 - 8.9e-59 198.4 15.9 1.2e-58 198.1 15.9 1.1 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEP18337.1 - 9.8e-27 94.0 0.3 1.5e-26 93.4 0.3 1.3 1 0 0 1 1 1 1 MIR domain Mucin_bdg PF03272.13 CEP18337.1 - 0.037 14.0 0.3 0.073 13.1 0.2 1.5 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module DUF4455 PF14643.6 CEP18339.1 - 0.034 12.8 0.3 0.05 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) CKS PF01111.19 CEP18340.1 - 1.6e-29 102.0 1.5 1.6e-29 102.0 1.5 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Roughex PF06020.11 CEP18340.1 - 3 6.8 6.1 7.1 5.6 6.1 1.6 1 0 0 1 1 1 0 Drosophila roughex protein DUF1664 PF07889.12 CEP18341.1 - 0.0059 16.6 0.9 0.02 14.9 0.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) V-SNARE PF05008.15 CEP18341.1 - 0.012 16.0 0.6 0.06 13.7 0.1 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Virulence_fact PF13769.6 CEP18341.1 - 0.015 15.6 0.1 0.024 14.8 0.1 1.4 1 1 0 1 1 1 0 Virulence factor DUF3919 PF13057.6 CEP18341.1 - 0.092 12.3 2.1 0.097 12.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Fzo_mitofusin PF04799.13 CEP18341.1 - 0.13 11.9 0.9 0.3 10.6 0.4 1.7 1 1 1 2 2 2 0 fzo-like conserved region SurA_N_3 PF13624.6 CEP18342.1 - 0.039 13.7 0.2 0.085 12.6 0.2 1.5 1 0 0 1 1 1 0 SurA N-terminal domain DUF2207 PF09972.9 CEP18342.1 - 0.062 12.1 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_3 PF13358.6 CEP18343.1 - 0.0094 15.7 0.0 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease MIR PF02815.19 CEP18344.1 - 2.6e-21 76.3 1.8 5.2e-21 75.3 1.6 1.6 1 1 0 1 1 1 1 MIR domain PIF1 PF05970.14 CEP18344.1 - 1.7e-12 47.2 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Fumble PF03630.14 CEP18344.1 - 0.098 11.8 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Fumble Response_reg PF00072.24 CEP18345.1 - 1.3e-26 92.9 0.6 5e-26 91.1 0.5 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 CEP18345.1 - 4.1e-16 59.4 2.9 4.1e-16 59.4 2.9 2.8 2 0 0 2 2 2 1 HSF-type DNA-binding Spt20 PF12090.8 CEP18345.1 - 2.2e-05 24.2 21.8 2.2e-05 24.2 21.8 3.9 3 1 0 3 3 3 1 Spt20 family Actin PF00022.19 CEP18346.1 - 1.6e-143 478.2 0.0 1.9e-143 477.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CEP18346.1 - 6.5e-05 21.9 0.0 0.31 9.8 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein CPSF100_C PF13299.6 CEP18346.1 - 0.025 14.8 3.4 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BLOC1S3 PF15753.5 CEP18346.1 - 0.76 9.9 12.3 1.9 8.6 2.1 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 HMGL-like PF00682.19 CEP18347.1 - 1.4e-96 323.1 0.3 2.8e-96 322.1 0.1 1.7 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 CEP18347.1 - 6.3e-21 74.7 3.2 1.1e-20 73.9 3.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF533 PF04391.12 CEP18347.1 - 0.0082 15.7 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Suv3_N PF18114.1 CEP18347.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Kinetochor_Ybp2 PF08568.10 CEP18348.1 - 2e-20 72.9 9.7 7.5e-19 67.7 9.7 2.7 1 1 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin zf-TFIIB PF13453.6 CEP18348.1 - 0.023 14.0 1.1 0.053 12.9 1.1 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger IBN_N PF03810.19 CEP18348.1 - 0.048 13.6 0.1 2.4 8.1 0.0 3.2 2 1 1 3 3 3 0 Importin-beta N-terminal domain Ham1p_like PF01725.16 CEP18349.1 - 1.7e-56 191.1 0.0 2e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family APH PF01636.23 CEP18350.1 - 6.5e-42 144.1 0.0 8.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CEP18350.1 - 8.6e-05 22.0 0.0 0.00026 20.4 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 CEP18350.1 - 0.0021 17.3 0.0 0.043 13.0 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 CEP18350.1 - 0.0029 17.2 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 CEP18350.1 - 0.053 13.1 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ni_hydr_CYTB PF01292.20 CEP18351.1 - 0.061 12.9 0.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Arm PF00514.23 CEP18352.1 - 1.5e-73 240.8 22.7 8.1e-12 44.8 0.1 10.3 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP18352.1 - 2.8e-20 72.5 9.1 1.6e-05 25.2 0.1 6.8 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 CEP18352.1 - 1.2e-17 64.0 18.5 0.00015 22.2 0.2 9.1 9 1 1 10 10 9 5 HEAT-like repeat Adaptin_N PF01602.20 CEP18352.1 - 4.2e-13 48.7 13.6 1.7e-10 40.1 1.9 2.3 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 CEP18352.1 - 4e-12 45.3 17.1 0.28 11.6 0.0 8.9 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 CEP18352.1 - 1.2e-09 38.1 7.7 3.2e-05 23.5 4.4 3.0 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 CEP18352.1 - 4.2e-09 35.2 3.0 6e-09 34.6 3.0 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 CEP18352.1 - 3.6e-07 29.8 8.3 0.0024 17.3 2.3 3.3 1 1 1 2 2 2 2 V-ATPase subunit H DUF3361 PF11841.8 CEP18352.1 - 9.1e-06 25.7 9.3 0.016 15.2 0.1 3.7 1 1 1 3 3 3 3 Domain of unknown function (DUF3361) Cnd1 PF12717.7 CEP18352.1 - 3.9e-05 23.7 8.9 0.32 11.0 0.1 4.2 2 2 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CEP18352.1 - 0.00028 21.0 9.1 1.9 8.6 0.1 5.0 3 1 3 6 6 6 3 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CEP18352.1 - 0.00074 20.1 1.2 1.4 9.5 0.3 3.9 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 CEP18352.1 - 0.016 15.8 12.1 40 5.3 0.0 7.9 8 1 0 8 8 7 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 CEP18352.1 - 0.017 15.1 8.5 3.4 7.6 0.3 4.5 3 1 2 5 5 5 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 CEP18352.1 - 0.054 13.7 3.2 7.1 6.9 0.1 3.8 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 CEP18352.1 - 0.054 13.5 7.9 0.16 12.0 0.3 4.4 2 2 5 7 7 7 0 Spinocerebellar ataxia type 10 protein domain RTTN_N PF14726.6 CEP18352.1 - 0.083 13.7 0.6 5.9 7.8 0.0 3.5 2 1 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning NopRA1 PF16201.5 CEP18352.1 - 0.69 9.5 8.8 10 5.6 0.4 3.9 4 0 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 DUF2052 PF09747.9 CEP18353.1 - 0.00033 20.9 3.2 0.00035 20.8 3.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Connexin PF00029.19 CEP18353.1 - 0.00085 19.1 1.9 0.0012 18.7 1.9 1.2 1 0 0 1 1 1 1 Connexin FAM176 PF14851.6 CEP18353.1 - 0.0016 18.1 4.3 0.0023 17.6 4.3 1.2 1 0 0 1 1 1 1 FAM176 family Radial_spoke PF04712.12 CEP18353.1 - 0.0017 17.4 0.9 0.002 17.2 0.9 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein DUF4193 PF13834.6 CEP18353.1 - 0.0024 18.3 0.8 0.0037 17.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) RNA_pol_Rpc4 PF05132.14 CEP18353.1 - 0.0045 17.4 1.0 0.0064 16.9 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Ribosomal_60s PF00428.19 CEP18353.1 - 0.0079 16.8 3.3 0.013 16.1 3.3 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein AP3D1 PF06375.11 CEP18353.1 - 0.009 16.3 13.7 0.014 15.7 13.7 1.3 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF2956 PF11169.8 CEP18353.1 - 0.01 16.0 7.0 0.01 16.0 7.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2956) DUF3464 PF11947.8 CEP18353.1 - 0.01 15.6 2.5 0.013 15.3 2.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PBP1_TM PF14812.6 CEP18353.1 - 0.02 15.2 4.6 0.036 14.4 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.10 CEP18353.1 - 0.021 14.2 11.7 0.032 13.6 11.7 1.2 1 0 0 1 1 1 0 BUD22 DNApol_Exo PF18136.1 CEP18353.1 - 0.025 13.7 1.5 0.032 13.4 1.5 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Pox_Ag35 PF03286.14 CEP18353.1 - 0.026 14.3 9.6 0.042 13.7 9.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 CEP18353.1 - 0.026 13.3 0.7 0.026 13.3 0.7 1.1 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 CEP18353.1 - 0.034 14.5 1.6 0.051 13.9 1.6 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Eapp_C PF10238.9 CEP18353.1 - 0.034 14.2 5.4 0.05 13.7 5.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF1682 PF07946.14 CEP18353.1 - 0.074 12.2 9.0 0.079 12.2 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DDHD PF02862.17 CEP18353.1 - 0.094 12.9 1.0 0.096 12.8 1.0 1.1 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.11 CEP18353.1 - 0.1 12.7 16.1 0.15 12.2 16.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4820 PF16091.5 CEP18353.1 - 0.1 11.9 3.6 0.11 11.8 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FancD2 PF14631.6 CEP18353.1 - 0.11 9.9 3.3 0.12 9.8 3.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NARP1 PF12569.8 CEP18353.1 - 0.11 11.4 8.9 0.12 11.2 8.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MAS20 PF02064.15 CEP18353.1 - 0.17 12.0 9.3 0.31 11.1 9.3 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF913 PF06025.12 CEP18353.1 - 0.18 10.7 2.7 0.24 10.4 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) OAD_gamma PF04277.13 CEP18353.1 - 0.19 12.4 4.6 0.35 11.5 4.6 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ureide_permease PF07168.11 CEP18353.1 - 0.21 10.3 1.7 0.26 10.0 1.7 1.1 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 CEP18353.1 - 0.21 11.1 6.2 0.34 10.4 6.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 S-antigen PF05756.11 CEP18353.1 - 0.25 11.7 11.3 0.12 12.7 8.8 1.7 1 1 1 2 2 2 0 S-antigen protein Afi1 PF07792.12 CEP18353.1 - 0.29 11.6 6.4 0.36 11.3 6.4 1.3 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SR-25 PF10500.9 CEP18353.1 - 0.37 10.4 15.5 0.62 9.6 15.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3824 PF12868.7 CEP18353.1 - 0.39 11.4 5.1 0.59 10.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RPN2_C PF18004.1 CEP18353.1 - 0.45 10.4 13.4 0.76 9.7 13.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Coilin_N PF15862.5 CEP18353.1 - 0.63 9.8 13.1 1.4 8.7 13.1 1.6 1 0 0 1 1 1 0 Coilin N-terminus MscS_TM PF12794.7 CEP18353.1 - 0.65 8.8 1.5 0.73 8.6 1.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Peroxin-13_N PF04088.13 CEP18353.1 - 0.67 10.2 2.2 0.92 9.8 2.2 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MAP17 PF15807.5 CEP18353.1 - 1.5 9.1 9.5 2.6 8.3 9.5 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Cytomega_UL84 PF06284.11 CEP18353.1 - 1.6 7.1 5.7 2.3 6.6 5.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Peptidase_S49_N PF08496.10 CEP18353.1 - 4.9 7.2 14.9 4.2 7.4 14.1 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Mito_carr PF00153.27 CEP18354.1 - 3.9e-62 206.2 3.2 6.2e-20 70.9 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 CEP18354.1 - 0.075 13.1 0.3 35 4.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) CENP-B_dimeris PF09026.10 CEP18355.1 - 1.8 9.0 11.5 6.9 7.1 11.5 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CEP18355.1 - 5.7 6.2 8.7 17 4.6 8.7 1.7 1 0 0 1 1 1 0 NOA36 protein HMG_box PF00505.19 CEP18356.1 - 1.1e-17 64.2 4.0 1.1e-17 64.2 4.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP18356.1 - 1.2e-09 38.7 2.9 1.2e-09 38.7 2.9 1.9 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 CEP18356.1 - 0.0002 21.2 0.0 0.00045 20.1 0.0 1.6 1 1 0 1 1 1 1 CHDNT (NUC034) domain BUD22 PF09073.10 CEP18356.1 - 0.23 10.8 22.2 0.26 10.6 22.2 1.1 1 0 0 1 1 1 0 BUD22 DUF515 PF04415.12 CEP18356.1 - 1.5 7.1 12.1 2.1 6.6 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cwf_Cwc_15 PF04889.12 CEP18356.1 - 6.4 6.4 21.1 6.4 6.4 20.5 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF908 PF06012.12 CEP18356.1 - 7.3 5.9 12.8 9 5.6 12.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Macoilin PF09726.9 CEP18356.1 - 7.9 4.9 16.0 8.5 4.8 16.0 1.2 1 0 0 1 1 1 0 Macoilin family HTH_29 PF13551.6 CEP18357.1 - 2.1e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 CEP18357.1 - 2.8e-05 24.6 0.0 4.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CEP18357.1 - 0.00024 20.8 0.0 0.023 14.5 0.2 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CEP18357.1 - 0.0015 18.6 0.2 0.0025 17.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 CEP18357.1 - 0.0078 16.5 0.0 0.47 10.8 0.1 2.2 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.27 CEP18359.1 - 4.6e-29 101.5 0.0 1e-28 100.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EamA PF00892.20 CEP18362.1 - 7.3e-11 42.4 20.9 8e-07 29.3 1.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CEP18362.1 - 1.8e-08 33.9 2.9 2.5e-08 33.4 2.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CEP18362.1 - 2e-07 30.7 6.8 0.00015 21.2 0.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 CEP18362.1 - 8.9e-06 25.1 11.8 1.3e-05 24.5 11.8 1.2 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CEP18362.1 - 2.2e-05 23.6 6.3 4.1e-05 22.7 0.2 2.9 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like Bax1-I PF01027.20 CEP18362.1 - 0.0012 18.7 5.0 0.0012 18.7 5.0 2.9 1 1 1 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 HEPN_SAV_6107 PF18726.1 CEP18362.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 SAV_6107-like HEPN PUNUT PF16913.5 CEP18362.1 - 0.11 11.7 11.8 0.092 12.0 8.7 2.4 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport PRAP PF15314.6 CEP18363.1 - 0.045 14.2 0.2 0.14 12.7 0.2 1.9 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine Pkinase PF00069.25 CEP18364.1 - 4.5e-72 242.6 0.0 4.5e-72 242.6 0.0 2.3 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18364.1 - 1.1e-48 165.8 0.0 3.1e-48 164.3 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CEP18364.1 - 2.1e-22 79.3 0.1 1.5e-21 76.5 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 CEP18364.1 - 8.3e-06 25.3 0.0 2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 CEP18365.1 - 2.5e-91 300.7 3.6 2.3e-20 72.8 0.1 6.4 6 0 0 6 6 6 6 C2 domain HLH PF00010.26 CEP18369.1 - 2.7e-10 40.0 0.0 9.3e-10 38.3 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Blo-t-5 PF11642.8 CEP18369.1 - 0.01 15.8 5.6 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Mite allergen Blo t 5 BPL_N PF09825.9 CEP18369.1 - 0.078 12.0 1.4 0.18 10.8 1.4 1.6 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PIF1 PF05970.14 CEP18372.1 - 9.9e-19 67.7 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP18372.1 - 0.00036 20.3 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP18372.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CEP18372.1 - 0.024 15.0 0.0 0.029 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CEP18372.1 - 0.026 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 CEP18372.1 - 0.034 13.4 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 CEP18372.1 - 0.045 13.3 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CEP18372.1 - 0.052 12.6 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 CEP18372.1 - 0.061 12.2 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 CEP18373.1 - 2.3e-32 112.6 0.0 2.4e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase CoA_transf_3 PF02515.17 CEP18374.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III Vps16_N PF04841.13 CEP18375.1 - 2e-106 356.2 0.0 2.8e-106 355.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CEP18375.1 - 4.8e-96 321.6 3.6 6.9e-96 321.0 3.6 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 CEP18375.1 - 2.1e-05 24.7 0.5 0.091 13.1 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain lci PF12197.8 CEP18375.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Nucleoporin_N PF08801.11 CEP18376.1 - 1.9e-52 178.5 5.7 2.8e-52 177.9 5.7 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CEP18376.1 - 9.4e-11 41.2 2.1 4.1e-10 39.0 2.1 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TPR_7 PF13176.6 CEP18376.1 - 0.003 17.5 0.5 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18376.1 - 0.06 13.5 0.5 0.19 11.9 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEP18376.1 - 0.069 13.0 0.1 0.26 11.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP18376.1 - 0.17 12.6 0.2 0.45 11.2 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S13 PF00416.22 CEP18377.1 - 5.3e-53 178.8 2.3 6.2e-53 178.6 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEP18377.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 CEP18377.1 - 0.048 12.7 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF2746 PF10874.8 CEP18377.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DPPIV_N PF00930.21 CEP18378.1 - 1.9e-100 336.1 7.7 2.9e-100 335.5 7.7 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CEP18378.1 - 1.7e-43 148.6 1.5 2.9e-43 147.8 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CEP18378.1 - 0.0012 18.5 0.5 0.0024 17.5 0.5 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CEP18378.1 - 0.017 15.7 0.2 0.033 14.8 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PKD_channel PF08016.12 CEP18379.1 - 0.00011 21.1 2.4 0.00015 20.6 2.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CEP18379.1 - 0.0022 17.3 5.3 0.0032 16.7 5.3 1.3 1 0 0 1 1 1 1 Ion transport protein DnaJ PF00226.31 CEP18380.1 - 4.9e-18 65.0 1.2 1.4e-17 63.6 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 CEP18380.1 - 5.9e-13 49.6 6.5 5.9e-13 49.6 6.5 3.8 4 0 0 4 4 4 1 Ribosome-associated complex head domain IPPT PF01715.17 CEP18380.1 - 3.3 7.5 8.9 2.8 7.7 7.0 1.7 1 1 1 2 2 2 0 IPP transferase Pkinase PF00069.25 CEP18381.1 - 0.0055 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cas_Cas4 PF01930.17 CEP18382.1 - 0.019 15.0 0.2 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF83 SNF2_N PF00176.23 CEP18383.1 - 5.7e-53 179.9 0.2 1.2e-43 149.2 0.2 2.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CEP18383.1 - 4.2e-13 49.6 0.0 1.2e-11 44.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP18383.1 - 2e-09 37.7 0.3 5e-09 36.4 0.3 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CEP18383.1 - 2.5e-06 27.4 0.1 5.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 CEP18383.1 - 0.00069 19.4 13.4 0.00069 19.4 13.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP18383.1 - 0.00072 19.4 11.2 0.00072 19.4 11.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CEP18383.1 - 0.034 14.2 9.1 0.13 12.3 9.1 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_14 PF17978.1 CEP18383.1 - 0.049 14.0 3.9 0.13 12.7 3.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SR-25 PF10500.9 CEP18383.1 - 0.26 10.9 6.4 5.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FlhC PF05280.11 CEP18383.1 - 4.3 7.0 9.0 5.9 6.6 0.7 2.6 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) FUSC PF04632.12 CEP18388.1 - 1.6 7.1 6.9 2.8 6.4 6.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 CEP18388.1 - 1.9 8.5 5.0 6.3 6.9 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V-ATPase_G PF03179.15 CEP18389.1 - 2.5e-29 101.9 16.7 2.9e-29 101.7 16.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CEP18389.1 - 0.023 14.8 8.6 0.023 14.8 8.6 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 CEP18389.1 - 0.027 14.9 16.6 0.055 13.9 16.6 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit M20_dimer PF07687.14 CEP18389.1 - 0.062 13.2 0.9 0.18 11.7 0.1 2.0 1 1 1 2 2 2 0 Peptidase dimerisation domain DUF2115 PF09888.9 CEP18389.1 - 0.18 12.3 6.7 0.24 11.9 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) CdiI_2 PF18593.1 CEP18389.1 - 0.18 12.5 2.2 0.52 11.0 0.4 2.0 1 1 1 2 2 2 0 CdiI immunity protein AcylCoA_dehyd_C PF12186.8 CEP18389.1 - 0.4 10.8 6.2 0.17 12.0 1.4 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF883 PF05957.13 CEP18389.1 - 0.71 10.5 12.5 0.78 10.4 4.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CemA PF03040.14 CEP18389.1 - 0.93 9.4 5.5 1.2 9.0 5.5 1.1 1 0 0 1 1 1 0 CemA family Seryl_tRNA_N PF02403.22 CEP18389.1 - 1.2 9.4 13.7 2.8 8.2 13.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PEP-utilisers_N PF05524.13 CEP18389.1 - 2.2 8.4 9.8 9.9 6.4 9.8 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4407 PF14362.6 CEP18389.1 - 2.8 7.2 11.3 3.4 7.0 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 CEP18389.1 - 8.6 5.7 6.4 37 3.6 6.4 1.8 1 1 0 1 1 1 0 Interactor of ZYG-11 Ribosomal_L3 PF00297.22 CEP18390.1 - 9.3e-186 617.2 13.0 1.1e-185 617.0 13.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PSP1 PF04468.12 CEP18391.1 - 2.1e-31 108.1 5.0 2.1e-31 108.1 5.0 2.4 3 0 0 3 3 3 1 PSP1 C-terminal conserved region Gpi1 PF05024.15 CEP18392.1 - 3.7e-72 242.4 12.6 9.6e-72 241.0 12.6 1.8 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) T5orf172 PF10544.9 CEP18393.1 - 6.9e-15 55.5 0.0 1.9e-14 54.0 0.0 1.7 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CEP18393.1 - 3.3e-11 43.7 0.0 6.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Pro_dh PF01619.18 CEP18394.1 - 7.5e-73 245.6 6.8 3.3e-72 243.5 6.8 1.9 1 1 0 1 1 1 1 Proline dehydrogenase OrfB_Zn_ribbon PF07282.11 CEP18395.1 - 0.028 14.3 1.0 0.065 13.2 1.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CDC37_N PF03234.14 CEP18395.1 - 0.21 12.5 0.1 0.21 12.5 0.1 2.8 4 0 0 4 4 4 0 Cdc37 N terminal kinase binding MFS_1 PF07690.16 CEP18396.1 - 6.6e-19 68.0 41.9 6.6e-19 68.0 41.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 CEP18397.1 - 6.8e-37 127.2 28.6 5.9e-34 117.5 10.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP18397.1 - 2.9e-08 33.0 5.6 2.9e-08 33.0 5.6 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 CEP18397.1 - 0.00018 21.0 7.2 0.001 18.4 4.8 3.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SieB PF14163.6 CEP18397.1 - 0.096 12.2 1.6 0.31 10.5 1.6 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B TPR_1 PF00515.28 CEP18398.1 - 1.3e-22 78.6 28.8 8.3e-05 22.2 0.1 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18398.1 - 2.6e-21 74.0 25.4 0.00047 20.1 0.2 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP18398.1 - 1.1e-16 59.5 16.8 0.0016 18.5 0.1 8.3 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP18398.1 - 5.6e-13 49.3 7.1 2.7e-05 24.7 0.4 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP18398.1 - 1e-11 44.9 17.6 0.003 17.8 0.3 7.2 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CEP18398.1 - 6.4e-09 35.9 5.2 0.3 12.0 0.0 6.7 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP18398.1 - 6.7e-09 35.3 7.1 0.005 16.5 0.1 6.3 5 2 2 7 7 7 3 TPR repeat TPR_19 PF14559.6 CEP18398.1 - 2.3e-07 31.2 6.8 0.00052 20.5 0.5 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP18398.1 - 2.3e-07 30.3 4.9 0.032 14.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEP18398.1 - 1.5e-06 28.2 1.0 0.0035 17.4 0.2 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP18398.1 - 7.9e-06 25.9 7.0 0.0029 17.9 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CEP18398.1 - 8.5e-05 21.9 1.7 3.8 6.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEP18398.1 - 0.001 19.4 2.8 0.29 11.5 0.3 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP18398.1 - 0.0035 16.8 2.4 0.27 10.6 0.1 3.8 3 1 1 5 5 5 1 MalT-like TPR region TPR_6 PF13174.6 CEP18398.1 - 0.0039 17.7 7.7 13 6.7 0.1 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CEP18398.1 - 0.0079 16.0 12.5 0.011 15.6 0.1 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 CEP18398.1 - 0.61 10.2 6.7 6.5 6.9 0.0 4.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 CEP18398.1 - 0.73 10.0 10.1 1.1 9.4 0.0 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 CEP18398.1 - 8 7.3 15.2 15 6.5 0.0 6.5 8 1 1 9 9 8 0 Sel1 repeat Carn_acyltransf PF00755.20 CEP18399.1 - 2.4e-208 693.5 0.0 2.7e-208 693.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Arg_decarbox_C PF17944.1 CEP18399.1 - 0.12 13.0 0.0 0.85 10.2 0.0 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension zf-C2H2 PF00096.26 CEP18400.1 - 2.3e-08 34.0 7.5 8e-05 22.9 0.3 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP18400.1 - 6.5e-06 26.3 18.2 0.00064 20.0 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 CEP18400.1 - 0.00053 20.3 5.9 0.00086 19.6 0.4 3.3 3 0 0 3 3 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CEP18400.1 - 0.00092 19.9 7.2 0.014 16.2 1.5 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP18400.1 - 0.004 17.4 0.6 0.004 17.4 0.6 3.7 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CEP18400.1 - 0.0076 16.5 0.5 0.024 14.9 0.5 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 CEP18400.1 - 0.024 14.5 3.1 0.6 10.1 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 CEP18400.1 - 0.085 12.9 10.2 0.2 11.7 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Trm112p PF03966.16 CEP18400.1 - 0.089 13.4 0.1 0.28 11.8 0.1 1.8 1 1 0 1 1 1 0 Trm112p-like protein zf-BED PF02892.15 CEP18400.1 - 0.11 12.5 1.3 14 5.8 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger TFIIA PF03153.13 CEP18400.1 - 0.11 12.4 11.6 0.17 11.9 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_ribbon_SprT PF17283.2 CEP18400.1 - 2.7 8.0 11.1 0.24 11.3 1.8 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-U1 PF06220.12 CEP18400.1 - 8.9 6.2 6.8 0.63 9.9 0.7 2.3 2 0 0 2 2 2 0 U1 zinc finger zf-CCHC_4 PF14392.6 CEP18401.1 - 0.16 11.7 0.6 0.29 10.9 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S10 PF00450.22 CEP18402.1 - 5.9e-114 381.7 0.2 7.3e-114 381.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RhoGEF PF00621.20 CEP18404.1 - 7.1e-32 111.1 0.7 1.2e-31 110.4 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain GrpE PF01025.19 CEP18405.1 - 1.2e-43 148.6 2.8 1.9e-43 148.0 2.8 1.3 1 1 0 1 1 1 1 GrpE PhetRS_B1 PF18262.1 CEP18405.1 - 0.011 15.9 0.6 0.11 12.7 0.0 2.5 2 1 1 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain DUF1664 PF07889.12 CEP18405.1 - 0.42 10.6 3.9 1.5 8.9 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) dCache_2 PF08269.11 CEP18405.1 - 4.6 6.3 7.4 5.3 6.1 4.9 2.0 2 0 0 2 2 2 0 Cache domain YlbD_coat PF14071.6 CEP18405.1 - 6.5 7.0 9.1 34 4.7 0.1 2.2 1 1 0 2 2 2 0 Putative coat protein Methyltransf_32 PF13679.6 CEP18406.1 - 4.5e-29 101.5 0.5 6.7e-29 100.9 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CEP18406.1 - 0.0046 16.1 0.2 0.93 8.5 0.0 2.3 1 1 1 2 2 2 2 DREV methyltransferase MTS PF05175.14 CEP18406.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CEP18406.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CEP18406.1 - 0.028 15.1 0.0 0.07 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 CEP18406.1 - 0.069 12.8 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 CEP18406.1 - 0.1 13.4 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18406.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.20 CEP18408.1 - 1.2e-100 337.2 0.0 1.3e-100 337.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Isochorismatase PF00857.20 CEP18409.1 - 6.9e-35 120.8 0.0 7.6e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Silic_transp PF03842.13 CEP18409.1 - 0.036 12.4 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter CIAPIN1 PF05093.13 CEP18410.1 - 9.8e-28 96.6 5.3 1.4e-27 96.1 4.4 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FBA_2 PF07735.17 CEP18410.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box associated PhoLip_ATPase_C PF16212.5 CEP18412.1 - 1.8e-75 254.0 29.9 3.3e-75 253.1 29.9 1.5 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP18412.1 - 1.9e-24 85.1 0.6 6.1e-24 83.5 0.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CEP18412.1 - 2.3e-13 50.0 0.0 8.3e-12 45.0 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP18412.1 - 9e-12 45.7 1.3 6.8e-07 29.8 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CEP18412.1 - 4.6e-06 26.3 0.0 4.6e-06 26.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP18412.1 - 0.0011 18.7 0.2 0.011 15.5 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ECH_2 PF16113.5 CEP18413.1 - 1.2e-95 320.9 0.1 1.6e-90 304.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEP18413.1 - 1.1e-24 87.2 0.0 1.7e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_42C PF08533.10 CEP18413.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain BRAP2 PF07576.12 CEP18415.1 - 2.9e-25 88.4 2.3 3.6e-25 88.1 0.5 2.0 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CEP18415.1 - 8.2e-18 64.5 8.5 8.2e-18 64.5 8.5 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CEP18415.1 - 3.9e-08 33.5 9.8 3.9e-08 33.5 9.8 2.4 2 1 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CEP18415.1 - 7.8e-07 29.1 1.7 7.8e-07 29.1 1.7 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CEP18415.1 - 2.6e-06 27.6 6.7 2.6e-06 27.6 6.7 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CEP18415.1 - 0.00011 22.1 7.9 0.00045 20.2 7.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CEP18415.1 - 0.00012 21.8 10.4 0.00012 21.8 10.4 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP18415.1 - 0.00039 20.2 8.6 0.00039 20.2 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CEP18415.1 - 0.0015 18.3 7.0 0.0015 18.3 7.0 2.2 3 0 0 3 3 1 1 RING-like zinc finger Golgin_A5 PF09787.9 CEP18415.1 - 0.024 14.1 12.0 0.04 13.4 12.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 NRBF2 PF08961.10 CEP18415.1 - 0.049 13.2 5.7 0.028 14.0 3.4 1.7 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator zf-C3HC4_3 PF13920.6 CEP18415.1 - 0.053 13.4 16.1 0.032 14.1 5.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YabA PF06156.13 CEP18415.1 - 0.28 11.8 8.7 0.16 12.6 4.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 CEP18415.1 - 0.33 11.4 7.9 0.81 10.1 7.9 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) zf-RING_4 PF14570.6 CEP18415.1 - 1.1 9.1 11.6 0.096 12.5 6.1 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TMF_TATA_bd PF12325.8 CEP18415.1 - 1.2 9.3 17.7 12 6.1 17.7 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 CEP18415.1 - 1.3 9.7 4.9 4.3 8.0 0.7 2.8 2 1 0 2 2 2 0 SlyX DUF3450 PF11932.8 CEP18415.1 - 1.5 8.1 15.0 1.2 8.4 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CEP18415.1 - 2.4 8.7 19.3 6.9 7.2 19.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 CEP18415.1 - 6.7 6.8 17.5 13 5.8 17.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2046 PF09755.9 CEP18416.1 - 2.1e-27 96.2 22.7 1.7e-26 93.2 20.6 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) YbaB_DNA_bd PF02575.16 CEP18416.1 - 0.0075 16.5 0.5 0.0075 16.5 0.5 2.1 2 1 0 2 2 2 1 YbaB/EbfC DNA-binding family LIM PF00412.22 CEP18417.1 - 5.2e-09 36.2 6.7 5.9e-09 36.0 6.7 1.1 1 0 0 1 1 1 1 LIM domain DUF4468 PF14730.6 CEP18417.1 - 0.0094 16.2 0.2 0.011 16.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4468) with TBP-like fold Nramp PF01566.18 CEP18418.1 - 3.8e-102 341.9 19.3 4.6e-102 341.6 19.3 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein YabA PF06156.13 CEP18419.1 - 4.2 8.1 5.8 0.89 10.2 0.2 2.7 3 1 0 3 3 3 0 Initiation control protein YabA Ribosomal_L24e PF01246.20 CEP18420.1 - 2.3e-13 50.2 0.1 2.3e-13 50.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e adh_short_C2 PF13561.6 CEP18421.1 - 1.7e-54 184.9 2.6 9.5e-54 182.4 2.6 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP18421.1 - 3.3e-48 163.7 4.2 1.3e-47 161.8 4.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP18421.1 - 2.6e-08 34.0 1.5 5.3e-08 33.0 1.5 1.5 1 1 0 1 1 1 1 KR domain Exotox-A_cataly PF09009.10 CEP18421.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Exotoxin A catalytic DUF1776 PF08643.10 CEP18421.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) bZIP_2 PF07716.15 CEP18422.1 - 1.3e-10 41.2 10.5 1.3e-10 41.2 10.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.9 CEP18422.1 - 0.028 14.6 2.8 0.069 13.4 2.8 1.6 1 0 0 1 1 1 0 Haemolysin XhlA EMP24_GP25L PF01105.24 CEP18422.1 - 0.04 13.9 0.0 6.7 6.6 0.6 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD bZIP_1 PF00170.21 CEP18422.1 - 1.7 8.8 15.2 0.11 12.6 9.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor Methyltransf_16 PF10294.9 CEP18424.1 - 1e-29 103.5 1.2 2.2e-29 102.4 1.2 1.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEP18424.1 - 0.00027 20.5 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CEP18424.1 - 0.00044 19.8 0.2 0.0008 18.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CEP18424.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEP18424.1 - 0.033 14.0 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Baculo_E56 PF04639.12 CEP18424.1 - 0.048 12.9 0.5 0.067 12.5 0.5 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope DHR-2 PF06920.13 CEP18425.1 - 1.8e-107 360.2 6.1 6.3e-107 358.4 6.1 2.0 1 0 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 CEP18425.1 - 1e-98 330.8 0.0 4.8e-98 328.5 0.0 2.3 2 0 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 CEP18425.1 - 1.4e-37 129.4 0.8 1.4e-37 129.4 0.8 4.9 5 1 0 5 5 5 1 C2 domain in Dock180 and Zizimin proteins HTH_23 PF13384.6 CEP18425.1 - 0.0092 15.8 0.0 0.037 13.8 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 CEP18425.1 - 0.029 14.5 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AIM24 PF01987.17 CEP18426.1 - 5.5e-13 49.2 0.0 6.6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 GSIII_N PF12437.8 CEP18428.1 - 1.8e-64 216.2 0.1 3.6e-64 215.3 0.1 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 CEP18428.1 - 5.4e-40 135.9 0.1 1.3e-39 134.7 0.1 1.7 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 CEP18428.1 - 8.5e-20 71.0 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Thi4 PF01946.17 CEP18429.1 - 1.3e-108 361.7 0.6 1.6e-108 361.4 0.6 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CEP18429.1 - 1.5e-09 37.9 0.4 1.6e-06 28.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CEP18429.1 - 1.7e-07 30.8 0.2 2.1e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CEP18429.1 - 2.4e-07 30.2 1.4 0.0002 20.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CEP18429.1 - 2.8e-06 27.5 0.2 9.4e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CEP18429.1 - 7.7e-05 22.7 0.2 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CEP18429.1 - 9.9e-05 21.6 0.7 0.00017 20.8 0.7 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 CEP18429.1 - 0.00015 21.2 0.8 0.00022 20.7 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CEP18429.1 - 0.00021 20.5 0.4 0.19 10.8 0.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 CEP18429.1 - 0.0052 15.5 0.1 0.0052 15.5 0.1 1.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CEP18429.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CEP18429.1 - 0.033 13.6 0.1 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Acetyltransf_1 PF00583.25 CEP18430.1 - 3e-11 43.6 0.1 4.4e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP18430.1 - 1.7e-08 34.8 0.1 2.8e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP18430.1 - 3.1e-08 33.6 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP18430.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CEP18430.1 - 0.002 18.2 0.0 0.0058 16.7 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 CEP18430.1 - 0.007 16.5 0.0 0.0089 16.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CEP18430.1 - 0.0074 16.4 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CEP18430.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CEP18430.1 - 0.14 12.8 0.1 0.2 12.3 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP18431.1 - 2.1e-09 37.4 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP18431.1 - 3.9e-09 36.8 0.0 5.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP18431.1 - 6e-08 33.0 0.0 9.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP18431.1 - 0.0021 18.0 0.0 0.0058 16.6 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CEP18431.1 - 0.0021 18.1 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 CEP18431.1 - 0.0079 15.7 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase PFK PF00365.20 CEP18432.1 - 4.7e-195 646.3 3.6 1.5e-108 362.5 0.9 2.2 2 0 0 2 2 2 2 Phosphofructokinase Mito_carr PF00153.27 CEP18432.1 - 1.4e-61 204.4 2.1 9.9e-22 76.7 0.0 4.4 4 0 0 4 4 4 3 Mitochondrial carrier protein Pfk_N PF18468.1 CEP18432.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CEP18432.1 - 0.15 11.7 0.1 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain E2F_TDP PF02319.20 CEP18433.1 - 2.2e-22 78.9 0.3 2.2e-22 78.9 0.3 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 CEP18433.1 - 9.3e-09 35.3 3.7 9.3e-09 35.3 3.7 2.2 2 0 0 2 2 2 1 Transcription factor DP IL15 PF02372.15 CEP18433.1 - 0.038 14.0 2.6 0.11 12.6 2.6 1.8 1 0 0 1 1 1 0 Interleukin 15 Activator_LAG-3 PF11498.8 CEP18433.1 - 0.15 11.0 30.2 0.23 10.4 30.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CEP18433.1 - 0.17 11.8 19.5 0.27 11.2 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 CEP18433.1 - 0.29 9.6 1.1 0.42 9.1 1.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 CEP18433.1 - 0.75 8.6 8.3 0.93 8.3 8.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CBS PF00571.28 CEP18434.1 - 9.7e-34 115.6 5.3 9.4e-09 35.6 0.0 5.6 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 CEP18434.1 - 8.2e-09 35.3 3.6 1.5e-07 31.3 3.6 2.6 1 1 0 1 1 1 1 PB1 domain NYN PF01936.18 CEP18434.1 - 0.036 14.5 1.0 0.073 13.5 0.3 1.8 2 0 0 2 2 2 0 NYN domain ATPase PF06745.13 CEP18434.1 - 1.4 8.2 4.1 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 KaiC zf-RVT PF13966.6 CEP18436.1 - 0.013 16.2 2.5 0.015 16.0 0.4 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Mu-like_Com PF10122.9 CEP18438.1 - 0.059 12.8 1.0 0.13 11.7 1.0 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com TCP PF03634.13 CEP18438.1 - 1.2 9.7 7.2 0.16 12.6 1.4 2.1 2 0 0 2 2 2 0 TCP family transcription factor Anti-TRAP PF15777.5 CEP18438.1 - 1.7 8.7 4.7 0.51 10.3 0.9 2.1 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein OrfB_Zn_ribbon PF07282.11 CEP18438.1 - 8.8 6.3 7.4 3.5 7.6 0.2 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Kelch_5 PF13854.6 CEP18439.1 - 4.6e-14 52.0 0.5 0.0023 17.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CEP18439.1 - 7.6e-14 51.4 6.1 0.085 13.2 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 CEP18439.1 - 6.5e-12 44.8 4.1 0.071 12.7 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CEP18439.1 - 2.3e-10 40.3 9.1 0.0085 16.1 0.1 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CEP18439.1 - 6.9e-07 29.4 6.4 2.5 8.5 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CEP18439.1 - 9.9e-07 28.5 0.6 1.9 8.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Gram_pos_anchor PF00746.21 CEP18439.1 - 0.091 12.7 1.0 0.22 11.5 0.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RVT_1 PF00078.27 CEP18441.1 - 4.5e-21 75.4 0.0 2.5e-09 37.0 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP18441.1 - 0.14 11.7 0.5 0.25 10.8 0.5 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family HNH PF01844.23 CEP18442.1 - 0.025 14.8 0.1 0.084 13.1 0.1 1.9 1 0 0 1 1 1 0 HNH endonuclease DEAD_assoc PF08494.11 CEP18442.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/H associated Mucin PF01456.17 CEP18442.1 - 0.72 9.8 6.9 1.7 8.6 6.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein HNH PF01844.23 CEP18443.1 - 0.0081 16.3 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease RRM_1 PF00076.22 CEP18443.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 CEP18444.1 - 8.1e-34 116.6 0.0 8.6e-34 116.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18444.1 - 3.5e-17 62.7 0.0 3.8e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP18444.1 - 3e-07 30.1 0.0 3.2e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CEP18444.1 - 0.011 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CEP18444.1 - 0.033 13.5 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP18444.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CEP18444.1 - 0.1 12.3 0.3 0.3 10.8 0.3 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation F-box-like PF12937.7 CEP18445.1 - 3.2e-07 30.1 0.1 1.2e-06 28.3 0.1 2.1 1 0 0 1 1 1 1 F-box-like PIH1_CS PF18201.1 CEP18445.1 - 0.033 14.6 0.2 4 7.9 0.0 3.2 3 0 0 3 3 3 0 PIH1 CS-like domain Zn_clus PF00172.18 CEP18447.1 - 8.4e-11 41.8 12.2 1.6e-10 40.9 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprA-related PF12118.8 CEP18447.1 - 0.015 14.5 35.7 0.042 13.0 15.0 2.4 2 0 0 2 2 2 0 SprA-related family eIF-3_zeta PF05091.12 CEP18447.1 - 0.45 9.4 28.0 0.077 12.0 11.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CEP18447.1 - 0.99 9.2 19.1 0.28 11.0 6.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4011 PF13195.6 CEP18447.1 - 1.2 9.1 7.8 8.5 6.3 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) EOS1 PF12326.8 CEP18447.1 - 2.6 7.9 9.6 0.56 10.1 1.3 2.5 2 0 0 2 2 2 0 N-glycosylation protein DUF4820 PF16091.5 CEP18447.1 - 2.7 7.3 16.2 0.56 9.5 5.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FYDLN_acid PF09538.10 CEP18447.1 - 7.1 7.4 10.3 16 6.2 3.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_L3 PF00297.22 CEP18448.1 - 1.7e-18 66.7 2.6 1.8e-15 56.8 0.5 2.5 1 1 2 3 3 3 2 Ribosomal protein L3 Utp14 PF04615.13 CEP18450.1 - 1.5 7.3 10.2 1.9 7.0 10.2 1.1 1 0 0 1 1 1 0 Utp14 protein Hamartin PF04388.12 CEP18450.1 - 5.1 5.6 25.4 7.4 5.1 25.4 1.2 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 CEP18452.1 - 1.8e-34 119.3 0.7 2.3e-26 92.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18452.1 - 4.5e-17 62.2 0.1 3.4e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP18452.1 - 0.00016 20.6 0.1 0.00038 19.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEP18452.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP18452.1 - 0.035 13.0 0.1 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Aldo_ket_red PF00248.21 CEP18453.1 - 1.3e-50 172.2 0.1 7.1e-49 166.6 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ArAE_2_N PF10337.9 CEP18454.1 - 1.9e-13 50.3 15.1 2e-10 40.4 3.3 3.1 1 1 2 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CEP18454.1 - 2.5e-12 47.1 0.1 5.3e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 CEP18454.1 - 1.4e-07 31.7 14.9 1.4e-07 31.7 14.9 3.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 CEP18454.1 - 4.4e-05 22.5 0.1 4.4e-05 22.5 0.1 2.3 3 1 1 4 4 4 1 Aluminium activated malate transporter FUSC PF04632.12 CEP18454.1 - 0.099 11.2 10.9 0.59 8.6 2.3 2.8 2 1 0 2 2 2 0 Fusaric acid resistance protein family Pkinase PF00069.25 CEP18455.1 - 2.8e-46 158.0 0.0 1.3e-45 155.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18455.1 - 4.2e-23 81.9 0.0 6.5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP18455.1 - 1.3e-05 24.7 0.2 0.00045 19.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CEP18455.1 - 0.0011 18.7 0.0 0.0053 16.4 0.0 2.1 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEP18455.1 - 0.021 13.6 0.2 0.03 13.1 0.2 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CEP18455.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family N-Term_TEN PF11474.8 CEP18456.1 - 0.0051 16.4 0.4 0.0068 16.0 0.4 1.1 1 0 0 1 1 1 1 Telomerase reverse transcriptase TEN domain UQ_con PF00179.26 CEP18457.1 - 7.6e-17 61.3 1.1 9.7e-17 60.9 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme PRESAN PF09687.10 CEP18457.1 - 0.21 12.2 0.1 0.21 12.2 0.1 3.1 3 1 0 3 3 3 0 Plasmodium RESA N-terminal CLASP_N PF12348.8 CEP18458.1 - 2.8e-37 128.5 2.1 2.8e-37 128.5 2.1 1.6 2 0 0 2 2 2 1 CLASP N terminal TAF6_C PF07571.13 CEP18458.1 - 0.00095 19.4 0.1 0.0029 17.9 0.1 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CEP18458.1 - 0.0081 16.3 0.0 7.4 7.1 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat Nrap_D2 PF17403.2 CEP18458.1 - 0.019 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Cohesin_HEAT PF12765.7 CEP18458.1 - 0.029 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion BC10 PF06726.12 CEP18458.1 - 0.063 13.5 0.7 0.21 11.8 0.2 2.2 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 RT_RNaseH PF17917.1 CEP18460.1 - 1.2e-27 96.2 0.0 2.7e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP18460.1 - 2e-24 85.5 0.0 4.9e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP18460.1 - 2.2e-23 82.9 0.1 4.3e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CEP18460.1 - 3.9e-05 24.1 0.5 9.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP18460.1 - 0.0018 18.9 0.0 0.0043 17.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CEP18460.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CEP18461.1 - 2.9e-08 33.9 4.3 4.6e-06 26.8 0.2 2.4 2 0 0 2 2 2 2 Retrotransposon gag protein zf-CCHC PF00098.23 CEP18461.1 - 5.2e-08 32.6 3.4 7.8e-08 32.0 3.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1473 PF07341.11 CEP18461.1 - 0.0088 15.8 1.4 0.49 10.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1473) NOG1 PF06858.14 CEP18461.1 - 0.043 13.6 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Coagulin PF02035.15 CEP18461.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Coagulin zf-CCHC_4 PF14392.6 CEP18461.1 - 0.08 12.7 0.5 0.19 11.5 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEP18461.1 - 0.11 12.4 0.5 0.24 11.2 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.9 CEP18462.1 - 5.8 6.4 5.7 7.6 6.1 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myb_DNA-bind_5 PF13873.6 CEP18463.1 - 0.0023 17.9 0.2 0.12 12.5 0.1 2.1 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain COX6A PF02046.15 CEP18464.1 - 3.4e-29 101.6 1.5 4.1e-29 101.3 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa S-layer PF07752.11 CEP18464.1 - 0.05 12.7 0.1 0.13 11.3 0.1 1.6 1 1 1 2 2 2 0 S-layer protein Tetraspanin PF00335.20 CEP18465.1 - 0.08 12.6 2.2 0.16 11.6 2.2 1.5 1 1 0 1 1 1 0 Tetraspanin family WD40 PF00400.32 CEP18466.1 - 5.2e-57 188.5 14.8 2.1e-08 34.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CEP18466.1 - 3.5e-27 94.5 8.4 5.7e-27 93.8 8.4 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CEP18466.1 - 6.6e-21 74.4 0.0 0.0011 19.2 0.0 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP18466.1 - 1.1e-10 41.0 0.1 0.024 13.6 0.0 5.1 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEP18466.1 - 4.9e-08 32.6 0.0 0.045 13.1 0.0 4.1 5 0 0 5 5 5 2 WD40-like domain PD40 PF07676.12 CEP18466.1 - 2.5e-05 24.1 0.3 7.2 6.7 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CEP18466.1 - 0.00013 20.7 0.1 0.0013 17.3 0.1 2.4 1 1 2 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.11 CEP18466.1 - 0.00018 21.4 0.0 2.7 7.8 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CEP18466.1 - 0.00052 19.4 0.1 3.4 6.9 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CEP18466.1 - 0.0018 17.0 0.9 2.2 6.8 0.0 4.5 2 1 3 5 5 5 1 Nucleoporin Nup120/160 Golgin_A5 PF09787.9 CEP18466.1 - 0.0054 16.2 4.6 0.0094 15.4 4.6 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 CEP18466.1 - 0.0098 14.8 5.0 0.015 14.2 5.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF724 PF05266.14 CEP18466.1 - 0.02 14.7 2.3 0.033 14.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 CEP18466.1 - 0.047 13.9 5.2 0.086 13.1 5.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF5122 PF17164.4 CEP18466.1 - 0.057 13.7 0.4 50 4.3 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller RasGAP_C PF03836.15 CEP18466.1 - 0.058 13.5 4.6 0.1 12.7 4.6 1.3 1 0 0 1 1 1 0 RasGAP C-terminus VID27 PF08553.10 CEP18466.1 - 0.11 11.5 0.0 13 4.7 0.0 2.8 2 1 0 3 3 3 0 VID27 C-terminal WD40-like domain Dna2 PF08696.11 CEP18466.1 - 0.11 12.3 0.7 0.2 11.4 0.7 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF3450 PF11932.8 CEP18466.1 - 1.6 7.9 7.3 3.4 6.9 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1640 PF07798.11 CEP18466.1 - 2.6 8.0 5.3 4.9 7.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Proteasome_A_N PF10584.9 CEP18466.1 - 5.6 6.8 6.5 9.1 6.1 0.0 4.0 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CP2 PF04516.15 CEP18467.1 - 8.2e-54 182.3 0.0 1.3e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor ATP-synt_ab PF00006.25 CEP18468.1 - 9.9e-64 214.9 0.0 2.1e-63 213.9 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEP18468.1 - 1.7e-23 82.9 2.5 3.2e-23 82.0 1.7 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 CEP18468.1 - 0.0089 15.2 0.7 0.016 14.4 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 CEP18468.1 - 0.01 15.7 0.1 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CEP18468.1 - 0.015 15.7 0.1 0.057 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CEP18468.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CEP18468.1 - 0.034 14.1 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T3SS_ATPase_C PF18269.1 CEP18468.1 - 0.034 14.0 0.8 0.22 11.4 0.8 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 CEP18468.1 - 0.036 13.4 0.1 0.07 12.5 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA PF00004.29 CEP18468.1 - 0.05 14.0 0.1 0.58 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CEP18468.1 - 0.056 13.8 0.8 0.29 11.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP18468.1 - 0.15 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_DE_N PF02823.16 CEP18469.1 - 2.7e-17 62.4 0.2 4e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1542 PF07564.11 CEP18469.1 - 0.086 13.0 2.0 12 6.1 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DHFR_1 PF00186.19 CEP18470.1 - 3.7e-19 69.0 0.0 5.4e-10 39.2 0.0 2.3 2 1 0 2 2 2 2 Dihydrofolate reductase Adaptin_N PF01602.20 CEP18471.1 - 6.9e-107 358.2 10.0 1e-106 357.6 10.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CEP18471.1 - 6.2e-62 207.3 0.1 2e-61 205.6 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CEP18471.1 - 5.3e-57 191.6 1.0 5.3e-57 191.6 1.0 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 CEP18471.1 - 9e-10 38.8 7.9 0.00043 20.6 0.0 5.1 2 1 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 CEP18471.1 - 9.5e-09 35.5 7.6 1.9e-05 24.7 0.0 3.8 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP18471.1 - 8.9e-06 25.5 1.1 0.019 15.2 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 CEP18471.1 - 7.2e-05 22.9 0.0 0.0004 20.5 0.0 2.4 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 CEP18471.1 - 0.00028 21.3 0.9 0.3 11.6 0.0 4.0 4 0 0 4 4 4 1 HEAT-like repeat DUF5578 PF17741.1 CEP18471.1 - 0.00078 18.9 3.4 0.047 13.1 1.6 2.9 2 1 1 3 3 3 1 Family of unknown function (DUF5578) DUF5071 PF16804.5 CEP18471.1 - 0.0016 18.7 0.9 0.13 12.6 0.0 3.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5071) BDV_G PF06208.11 CEP18471.1 - 0.0025 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Borna disease virus G protein FAD-oxidase_C PF02913.19 CEP18472.1 - 4e-63 213.4 0.0 5.4e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEP18472.1 - 1.3e-36 125.4 0.0 2.9e-36 124.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain CAP_GLY PF01302.25 CEP18473.1 - 3e-18 65.6 0.0 4.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.31 CEP18473.1 - 5.1e-17 62.1 0.9 1.6e-12 47.6 0.3 2.8 2 0 0 2 2 2 2 BTB/POZ domain COG4 PF08318.12 CEP18474.1 - 1.3e-88 297.3 2.8 1.3e-88 297.3 2.8 1.7 2 0 0 2 2 2 1 COG4 transport protein DNTTIP1_dimer PF18192.1 CEP18474.1 - 0.0066 16.8 0.2 0.037 14.4 0.2 2.4 1 0 0 1 1 1 1 DNTTIP1 dimerisation domain DUF4164 PF13747.6 CEP18474.1 - 0.066 13.5 7.7 0.032 14.5 2.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Fez1 PF06818.15 CEP18474.1 - 0.12 12.8 5.3 0.52 10.7 5.3 2.1 1 0 0 1 1 1 0 Fez1 zf-C4H2 PF10146.9 CEP18474.1 - 0.16 12.2 1.4 0.53 10.6 0.3 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein FapA PF03961.13 CEP18474.1 - 1 7.9 3.5 1.9 7.0 3.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A WD40 PF00400.32 CEP18475.1 - 1.3e-15 57.5 13.9 0.012 16.5 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18475.1 - 9.8e-07 29.0 0.0 0.014 15.7 0.0 5.0 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP18475.1 - 0.018 14.0 0.0 16 4.3 0.0 3.4 1 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Isy1 PF06246.12 CEP18475.1 - 0.02 14.5 10.2 0.047 13.2 10.2 1.5 1 0 0 1 1 1 0 Isy1-like splicing family DUF3659 PF12396.8 CEP18475.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) PP_M1 PF03012.14 CEP18475.1 - 1.6 8.2 7.7 2.8 7.4 7.7 1.3 1 0 0 1 1 1 0 Phosphoprotein RVT_1 PF00078.27 CEP18476.1 - 0.00023 20.8 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP18478.1 - 0.025 15.3 1.5 0.026 15.2 0.2 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Histone_H2A_C PF16211.5 CEP18478.1 - 0.18 11.5 0.3 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 C-terminus of histone H2A PPR_2 PF13041.6 CEP18479.1 - 2.1e-27 95.0 4.3 8e-07 29.2 0.0 6.5 5 2 2 7 7 7 6 PPR repeat family PPR_1 PF12854.7 CEP18479.1 - 8.1e-13 47.8 4.0 0.0043 16.7 0.0 6.4 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.6 CEP18479.1 - 6.9e-10 38.9 5.7 0.4 10.8 0.0 5.9 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 CEP18479.1 - 7.4e-07 29.0 6.6 0.0063 16.7 0.0 7.0 7 1 0 7 7 7 1 PPR repeat PPR_long PF17177.4 CEP18479.1 - 0.00013 21.4 0.5 0.036 13.4 0.0 3.5 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP ANAPC3 PF12895.7 CEP18479.1 - 0.017 15.3 0.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RST PF12174.8 CEP18479.1 - 0.033 14.1 0.1 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Fis1_TPR_C PF14853.6 CEP18479.1 - 0.054 13.6 1.2 0.21 11.7 0.5 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CEP18479.1 - 0.096 13.2 1.6 15 6.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP18479.1 - 0.15 12.8 4.2 1 10.2 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18479.1 - 0.15 12.2 0.5 0.61 10.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.6 CEP18480.1 - 6.1e-22 78.1 0.0 1.2e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CEP18480.1 - 1.1e-12 47.9 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CEP18480.1 - 6.2e-08 33.0 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Toprim_2 PF13155.6 CEP18480.1 - 1.9e-05 25.0 0.0 5.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 CEP18480.1 - 9.3e-05 22.8 0.0 0.047 14.2 0.0 2.6 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 CEP18480.1 - 0.00027 20.3 0.0 0.00082 18.8 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 CEP18480.1 - 0.00032 21.1 0.0 0.0008 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CEP18480.1 - 0.00049 20.6 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 CEP18480.1 - 0.004 17.7 0.3 0.004 17.7 0.3 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CEP18480.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.6 CEP18480.1 - 0.0062 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP18480.1 - 0.011 15.6 0.0 0.07 13.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 CEP18480.1 - 0.037 14.3 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CEP18480.1 - 0.05 13.3 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CEP18480.1 - 0.07 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CEP18480.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 CEP18480.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CEP18480.1 - 0.13 12.1 1.1 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 NTPase Arf PF00025.21 CEP18480.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Zn_Tnp_IS1595 PF12760.7 CEP18480.1 - 0.15 12.0 0.9 0.34 10.9 0.9 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNA_pol_Rpc82 PF05645.13 CEP18481.1 - 1.2e-09 38.3 1.9 4.4e-08 33.2 1.9 2.4 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CEP18481.1 - 2.5e-05 24.3 0.3 0.0026 17.8 0.1 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_9 PF08221.11 CEP18482.1 - 5.1e-20 71.3 0.0 2.9e-15 56.1 0.1 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RVT_1 PF00078.27 CEP18483.1 - 2.8e-16 59.7 0.0 3.7e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gal4_dimer PF03902.13 CEP18483.1 - 0.042 14.0 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Plasmod_dom_1 PF09715.10 CEP18483.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) MAP7 PF05672.11 CEP18486.1 - 0.28 10.8 24.4 0.023 14.4 18.1 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family NOA36 PF06524.12 CEP18487.1 - 0.18 11.1 7.5 0.24 10.7 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein JmjC PF02373.22 CEP18488.1 - 1.4e-17 64.1 0.0 4.1e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CEP18488.1 - 0.00044 20.1 0.0 0.0062 16.3 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain C1_2 PF03107.16 CEP18488.1 - 0.015 15.6 5.4 0.015 15.6 5.4 3.2 4 0 0 4 4 4 0 C1 domain ZZ PF00569.17 CEP18488.1 - 0.016 15.0 12.8 0.016 15.0 12.8 3.3 3 0 0 3 3 3 0 Zinc finger, ZZ type Cupin_2 PF07883.11 CEP18488.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Desulfoferrod_N PF06397.12 CEP18488.1 - 6.5 6.5 8.2 1.8 8.3 0.1 3.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain RabGAP-TBC PF00566.18 CEP18489.1 - 6.5e-50 169.8 1.1 6.5e-50 169.8 1.1 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SPAM PF02090.15 CEP18489.1 - 0.0053 16.6 7.3 0.0053 16.6 7.3 2.4 1 1 1 2 2 2 1 Salmonella surface presentation of antigen gene type M protein DUF724 PF05266.14 CEP18489.1 - 0.0078 16.1 8.7 0.0078 16.1 8.7 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF724) DUF4201 PF13870.6 CEP18489.1 - 0.074 12.8 20.8 0.11 12.2 11.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 CEP18489.1 - 0.098 12.7 22.9 0.53 10.3 19.8 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gp-FAR-1 PF05823.12 CEP18489.1 - 0.1 12.9 12.5 0.11 12.8 0.8 4.0 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BRE1 PF08647.11 CEP18489.1 - 0.11 12.6 21.8 0.57 10.3 2.7 3.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 CEP18489.1 - 0.12 12.4 9.0 0.046 13.8 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 CEP18489.1 - 0.16 12.2 20.0 0.34 11.1 9.0 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.15 CEP18489.1 - 1 9.5 9.6 4.1 7.5 1.3 2.8 1 1 1 2 2 2 0 RasGAP C-terminus Bap31_Bap29_C PF18035.1 CEP18489.1 - 2.5 8.2 10.3 4.6 7.3 1.5 3.9 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cep57_CLD_2 PF14197.6 CEP18489.1 - 3.9 7.6 22.3 0.19 11.8 10.1 4.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 CEP18489.1 - 4.4 7.4 22.6 0.47 10.5 16.5 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 CEP18489.1 - 5.4 5.4 5.6 9 4.7 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CtIP_N PF10482.9 CEP18489.1 - 6 6.9 13.8 5.1 7.2 0.3 3.7 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 CEP18489.1 - 7.1 7.1 31.6 4.3 7.9 1.3 5.4 4 1 2 6 6 6 0 Cell division protein ZapB DUF2205 PF10224.9 CEP18489.1 - 7.9 6.6 12.0 0.36 10.8 1.6 3.4 3 1 1 4 4 4 0 Short coiled-coil protein MYEOV2 PF15004.6 CEP18490.1 - 3e-07 30.8 2.3 3e-07 30.8 2.3 2.3 2 1 1 3 3 3 1 Myeloma-overexpressed-like HGTP_anticodon PF03129.20 CEP18491.1 - 2.2e-22 79.0 0.0 4.1e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CEP18491.1 - 2.7e-07 30.7 0.1 6.4e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Smg8_Smg9 PF10220.9 CEP18493.1 - 2.6e-89 300.7 6.7 2.1e-39 135.6 4.8 5.0 5 0 0 5 5 5 5 Smg8_Smg9 FOLN PF09289.10 CEP18493.1 - 2.8 8.2 4.9 4.9 7.4 1.6 2.5 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain PQ-loop PF04193.14 CEP18494.1 - 9.8e-20 70.1 13.9 2.4e-12 46.4 1.9 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF2530 PF10745.9 CEP18494.1 - 0.49 10.7 7.7 0.23 11.7 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) WCOR413 PF05562.11 CEP18494.1 - 1.4 8.8 8.1 0.36 10.7 3.1 2.4 1 1 2 3 3 3 0 Cold acclimation protein WCOR413 MtN3_slv PF03083.16 CEP18494.1 - 2.5 8.2 13.3 7 6.8 2.8 2.9 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange E1-E2_ATPase PF00122.20 CEP18495.1 - 1.5e-26 93.0 0.7 3.8e-26 91.7 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CEP18495.1 - 4.3e-12 46.8 0.0 1.3e-06 28.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP18495.1 - 0.00017 21.2 0.4 0.00049 19.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP18495.1 - 0.0099 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF4707 PF15806.5 CEP18495.1 - 0.01 14.8 0.2 0.017 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) VbhA PF18495.1 CEP18495.1 - 0.036 13.9 0.1 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 Antitoxin VbhA Hydrolase_3 PF08282.12 CEP18495.1 - 0.065 13.0 2.4 0.47 10.2 0.0 3.1 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Mannosyl_trans2 PF04188.13 CEP18496.1 - 4.7e-57 194.3 24.9 6.1e-57 193.9 24.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF4315 PF14193.6 CEP18497.1 - 0.022 14.8 2.2 0.041 13.9 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Ank_2 PF12796.7 CEP18498.1 - 4.2e-31 107.4 0.9 1.4e-14 54.4 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP18498.1 - 1.2e-27 95.9 1.0 1e-11 45.1 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP18498.1 - 2.9e-22 78.4 2.3 1.2e-06 28.6 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP18498.1 - 4e-21 72.9 2.3 6.2e-05 23.1 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CEP18498.1 - 1.9e-19 69.2 1.8 9.7e-05 22.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 CEP18498.1 - 1.3e-17 63.7 6.3 2.4e-17 62.8 6.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CEP18498.1 - 1.1e-05 25.6 1.2 1.1e-05 25.6 1.2 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger Pex24p PF06398.11 CEP18498.1 - 0.014 14.4 6.4 0.022 13.8 6.4 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MIT PF04212.18 CEP18498.1 - 0.033 14.2 0.1 0.088 12.9 0.1 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain C1_2 PF03107.16 CEP18498.1 - 0.058 13.7 5.0 0.2 12.0 5.0 1.9 1 0 0 1 1 1 0 C1 domain AAA_12 PF13087.6 CEP18498.1 - 0.067 12.8 2.0 0.12 12.0 2.0 1.3 1 0 0 1 1 1 0 AAA domain MscS_TM PF12794.7 CEP18498.1 - 0.41 9.5 1.9 0.67 8.8 1.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sel1 PF08238.12 CEP18499.1 - 1.9e-17 63.3 25.1 2.6e-06 27.9 0.3 8.2 8 0 0 8 8 8 4 Sel1 repeat TPR_2 PF07719.17 CEP18499.1 - 0.00021 21.2 3.0 0.0023 17.9 0.5 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CEP18499.1 - 0.00025 20.8 0.7 0.0018 18.2 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP18499.1 - 0.0019 17.9 0.3 0.0019 17.9 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP18499.1 - 0.0027 18.4 1.0 0.045 14.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP18499.1 - 0.33 11.7 6.1 4.3 8.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 CEP18499.1 - 0.33 10.6 2.0 1.9 8.1 0.1 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 DIL PF01843.19 CEP18500.1 - 9.7e-29 99.7 2.3 4.1e-28 97.7 2.3 2.2 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CEP18500.1 - 5.3e-14 52.6 0.1 1.2e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CEP18500.1 - 8.1e-11 41.9 0.2 6.7e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CEP18500.1 - 9.8e-10 38.8 0.7 9.9e-06 26.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP18500.1 - 1.8e-08 34.5 0.1 0.00018 21.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP18500.1 - 1.2e-06 28.4 0.1 0.016 15.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat SOCS_box PF07525.16 CEP18500.1 - 0.098 13.0 0.3 0.34 11.3 0.3 2.0 1 0 0 1 1 1 0 SOCS box DUF2729 PF10870.8 CEP18500.1 - 0.15 11.9 0.8 0.59 10.0 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DUF1168 PF06658.12 CEP18501.1 - 2.9e-40 137.2 17.1 2.9e-40 137.2 17.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Pecanex_C PF05041.15 CEP18501.1 - 0.026 14.1 0.1 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Pecanex protein (C-terminus) Serglycin PF04360.12 CEP18501.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.3 1 1 0 1 1 1 0 Serglycin DHDPS PF00701.22 CEP18504.1 - 2.7e-47 160.9 0.0 3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_19 PF14559.6 CEP18504.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 CEP18505.1 - 1.4e-25 89.5 0.4 2.7e-25 88.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Opi1 PF08618.10 CEP18506.1 - 8.2e-59 199.9 12.2 7.3e-49 167.1 8.6 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 Pex14_N PF04695.13 CEP18506.1 - 0.5 11.0 4.4 0.18 12.5 1.4 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fes1 PF08609.10 CEP18506.1 - 1.1 10.1 3.3 2.7 8.9 0.0 2.7 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 IPK PF03770.16 CEP18507.1 - 8.9e-46 156.2 0.1 8.9e-46 156.2 0.1 2.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase PAT1 PF09770.9 CEP18507.1 - 0.0014 17.1 7.6 0.0014 17.1 7.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 CEP18507.1 - 0.0022 17.5 5.6 0.0027 17.2 5.6 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CEP18507.1 - 0.0024 16.7 4.8 0.0028 16.5 4.8 1.2 1 0 0 1 1 1 1 Presenilin TERB2 PF15101.6 CEP18507.1 - 0.0051 16.9 8.9 0.0051 16.9 8.9 1.6 2 0 0 2 2 1 1 Telomere-associated protein TERB2 DUF2722 PF10846.8 CEP18507.1 - 0.0098 14.9 24.6 0.014 14.3 24.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4471 PF14740.6 CEP18507.1 - 0.026 13.7 2.5 0.036 13.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) MDM10 PF12519.8 CEP18507.1 - 0.098 11.5 3.5 0.12 11.2 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CCDC53 PF10152.9 CEP18507.1 - 0.2 12.1 11.9 0.091 13.2 8.8 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 CEP18507.1 - 0.24 11.4 28.1 0.38 10.7 28.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CEP18507.1 - 0.25 10.0 3.4 0.28 9.8 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prothymosin PF03247.14 CEP18507.1 - 0.25 11.8 14.6 0.51 10.8 14.6 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF913 PF06025.12 CEP18507.1 - 0.26 10.2 5.8 0.49 9.3 5.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 CEP18507.1 - 0.36 10.1 8.6 0.54 9.5 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM150 PF15129.6 CEP18507.1 - 0.44 10.7 8.9 1.1 9.5 8.9 1.6 1 0 0 1 1 1 0 FAM150 family Eapp_C PF10238.9 CEP18507.1 - 0.66 10.0 12.4 0.43 10.6 10.0 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein OATP PF03137.20 CEP18507.1 - 0.88 7.8 3.3 1.2 7.3 3.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CMS1 PF14617.6 CEP18507.1 - 1.4 8.2 4.9 2.5 7.4 4.9 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Zip PF02535.22 CEP18507.1 - 1.7 7.8 3.3 2.1 7.5 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.6 CEP18507.1 - 2.6 7.7 9.9 0.9 9.2 7.0 1.6 2 0 0 2 2 2 0 FAM176 family CTU2 PF10288.9 CEP18507.1 - 2.8 8.2 13.8 4.5 7.5 9.2 2.8 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 V_ATPase_I PF01496.19 CEP18507.1 - 3.6 5.4 12.5 5.2 4.8 12.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Endostatin PF06482.11 CEP18507.1 - 4.9 6.5 11.6 1.8 8.0 9.3 1.4 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Ureide_permease PF07168.11 CEP18507.1 - 8.3 5.0 6.4 15 4.2 6.4 1.3 1 0 0 1 1 1 0 Ureide permease GNAT_acetyltr_2 PF13718.6 CEP18507.1 - 9 5.6 9.9 17 4.7 9.9 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SET PF00856.28 CEP18508.1 - 8.1e-14 52.4 0.2 1.6e-13 51.4 0.2 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CEP18508.1 - 0.00089 19.3 13.6 0.00089 19.3 13.6 2.0 2 0 0 2 2 2 1 MYND finger HTH_21 PF13276.6 CEP18508.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain Lipocalin_5 PF13924.6 CEP18508.1 - 0.09 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Lipocalin-like domain FYVE_2 PF02318.16 CEP18508.1 - 3.2 8.0 9.4 3.9 7.7 6.1 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Myb_DNA-binding PF00249.31 CEP18509.1 - 2.9e-38 129.8 5.4 2.9e-15 56.2 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP18509.1 - 7.4e-34 115.8 0.4 4.8e-16 58.7 0.0 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain MCM_bind PF09739.9 CEP18509.1 - 0.0042 15.6 15.1 0.0059 15.1 15.1 1.2 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor PAT1 PF09770.9 CEP18509.1 - 0.022 13.1 21.3 0.027 12.8 21.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 CEP18509.1 - 0.044 14.0 7.4 0.093 12.9 7.4 1.6 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 CEP18509.1 - 0.058 12.2 10.3 0.08 11.7 10.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Merozoite_SPAM PF07133.11 CEP18509.1 - 0.061 13.3 20.1 0.1 12.6 20.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Suf PF05843.14 CEP18509.1 - 0.15 12.0 17.3 0.25 11.3 17.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PTPRCAP PF15713.5 CEP18509.1 - 0.76 10.1 19.8 1.6 9.0 19.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 CEP18509.1 - 0.99 8.8 14.7 2 7.8 14.7 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 CEP18509.1 - 1 10.0 27.8 0.28 11.8 24.6 1.7 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1644 PF07800.12 CEP18509.1 - 1.1 9.3 10.1 0.7 9.9 7.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) RR_TM4-6 PF06459.12 CEP18509.1 - 1.2 8.8 21.2 2 8.2 21.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 CEP18509.1 - 1.9 8.5 13.5 3.6 7.5 13.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 CEP18509.1 - 1.9 7.4 17.7 2.8 6.8 17.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 CEP18509.1 - 2.3 8.4 13.2 4.6 7.4 13.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.13 CEP18509.1 - 2.6 7.8 14.2 4.6 7.0 14.2 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CEP18509.1 - 2.8 6.8 24.1 4.3 6.2 24.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 CEP18509.1 - 2.9 6.1 23.1 4.8 5.3 23.1 1.2 1 0 0 1 1 1 0 CDC45-like protein EMC3_TMCO1 PF01956.16 CEP18509.1 - 4 7.1 9.8 6.3 6.5 9.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4569 PF15133.6 CEP18509.1 - 5.3 6.7 20.7 9.2 5.9 20.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) PA26 PF04636.13 CEP18509.1 - 5.5 5.8 15.0 8.1 5.3 15.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PepSY_TM PF03929.16 CEP18509.1 - 8 6.0 7.7 13 5.4 7.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM region CLN3 PF02487.17 CEP18509.1 - 9.5 5.1 9.9 14 4.6 9.9 1.2 1 0 0 1 1 1 0 CLN3 protein GUB_WAK_bind PF13947.6 CEP18510.1 - 0.055 14.2 0.5 0.23 12.2 0.1 2.2 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding eIF_4EBP PF05456.11 CEP18511.1 - 5.4e-08 32.8 0.1 6.2e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Abhydrolase_3 PF07859.13 CEP18512.1 - 1.6e-57 194.8 0.0 2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CEP18512.1 - 7.1e-08 31.8 0.1 0.00088 18.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Say1_Mug180 PF10340.9 CEP18512.1 - 9.6e-08 31.3 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 CEP18512.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAAT_C PF08840.11 CEP18512.1 - 0.071 13.0 0.3 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 CEP18512.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 CEP18512.1 - 0.21 11.2 0.0 22 4.6 0.0 2.4 2 0 0 2 2 2 0 Putative esterase MFS_1 PF07690.16 CEP18513.1 - 1.1e-13 50.8 58.1 1.9e-13 50.1 56.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CEP18513.1 - 0.002 16.6 32.5 0.003 16.0 32.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CEP18514.1 - 1.2e-10 40.8 8.3 1.7e-10 40.3 8.3 1.2 1 0 0 1 1 1 1 MFS_1 like family Presenilin PF01080.17 CEP18514.1 - 0.044 12.5 9.0 0.079 11.7 9.0 1.4 1 0 0 1 1 1 0 Presenilin AA_permease_2 PF13520.6 CEP18516.1 - 7.7e-54 183.1 42.3 9.7e-54 182.8 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CEP18516.1 - 7.6e-20 70.9 35.0 1.2e-19 70.3 35.0 1.2 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.20 CEP18517.1 - 9.4e-13 47.9 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF383 PF04063.14 CEP18518.1 - 9.3e-58 195.0 0.5 2.6e-57 193.6 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CEP18518.1 - 9.8e-18 63.8 0.3 3.7e-17 61.9 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF384) STI1 PF17830.1 CEP18518.1 - 0.0035 17.3 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 STI1 domain RICTOR_M PF14666.6 CEP18518.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain PAC1 PF16094.5 CEP18519.1 - 4.8e-15 55.5 0.2 7.7e-15 54.8 0.2 1.4 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Dna2 PF08696.11 CEP18521.1 - 5.8e-59 199.3 0.7 1.1e-58 198.5 0.7 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CEP18521.1 - 7.4e-53 179.1 0.5 6.1e-52 176.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CEP18521.1 - 1.8e-31 109.9 0.0 3.5e-17 63.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain NTF2 PF02136.20 CEP18521.1 - 9.6e-23 81.0 0.2 4.1e-22 79.0 0.1 2.2 2 0 0 2 2 1 1 Nuclear transport factor 2 (NTF2) domain AAA_30 PF13604.6 CEP18521.1 - 1.5e-13 50.9 0.0 3.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP18521.1 - 2.2e-10 41.1 0.1 6.6e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 CEP18521.1 - 7e-07 29.5 0.5 8.6e-06 25.9 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF83 Mtr2 PF10429.9 CEP18521.1 - 1.2e-06 28.5 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Helicase_RecD PF05127.14 CEP18521.1 - 9.7e-06 25.5 0.0 0.00011 22.2 0.0 2.5 2 0 0 2 2 2 1 Helicase PDDEXK_1 PF12705.7 CEP18521.1 - 5.7e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 CEP18521.1 - 6.5e-05 22.8 0.1 0.67 9.6 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CEP18521.1 - 0.0004 20.1 0.0 0.00096 18.8 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 CEP18521.1 - 0.00089 19.3 0.8 0.0086 16.1 0.1 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 CEP18521.1 - 0.0041 16.3 0.0 0.094 11.9 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 CEP18521.1 - 0.0043 16.6 1.1 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 CEP18521.1 - 0.016 15.2 0.1 0.075 13.0 0.0 2.2 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CEP18521.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 CEP18521.1 - 0.02 14.7 0.0 0.063 13.1 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF87 PF01935.17 CEP18521.1 - 0.02 15.0 1.1 0.15 12.1 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_16 PF13191.6 CEP18521.1 - 0.031 14.7 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain PEPCK_ATP PF01293.20 CEP18521.1 - 0.031 12.9 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 CEP18521.1 - 0.038 13.6 0.1 0.18 11.4 0.0 2.1 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 CEP18521.1 - 0.039 13.3 0.0 0.13 11.5 0.0 1.9 1 0 0 1 1 1 0 KaiC AAA PF00004.29 CEP18521.1 - 0.046 14.1 0.1 0.24 11.8 0.1 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CEP18521.1 - 0.049 13.7 0.7 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C PF13361.6 CEP18521.1 - 0.058 12.8 0.0 12 5.1 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Csa1 PF06023.12 CEP18521.1 - 0.082 12.3 0.2 0.28 10.5 0.2 1.9 2 0 0 2 2 2 0 CRISPR-associated exonuclease Csa1 Rap_GAP PF02145.15 CEP18522.1 - 4.5e-38 130.7 0.0 4.5e-27 94.8 0.0 2.7 1 1 1 2 2 2 2 Rap/ran-GAP G-alpha PF00503.20 CEP18523.1 - 8.8e-118 393.5 4.1 1.1e-117 393.2 4.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP18523.1 - 5.3e-16 58.6 0.3 4.8e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP18523.1 - 4.6e-05 22.9 2.7 0.0038 16.6 0.0 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP18523.1 - 0.003 17.8 0.1 1.8 8.8 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 CEP18523.1 - 0.011 15.5 0.1 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 CHC2 zinc finger MCM PF00493.23 CEP18523.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 CEP18523.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CEP18523.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ank_2 PF12796.7 CEP18524.1 - 4.6e-26 91.2 11.4 2e-07 31.5 0.2 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) VPS9 PF02204.18 CEP18524.1 - 4.3e-17 62.2 0.0 1.4e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.6 CEP18524.1 - 2.5e-14 53.4 11.6 0.0013 19.3 0.0 6.6 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 CEP18524.1 - 2.4e-13 49.9 17.8 0.009 16.4 1.5 7.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 CEP18524.1 - 4.1e-13 48.2 11.4 0.62 10.8 0.0 8.6 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 CEP18524.1 - 6.5e-09 35.9 14.1 0.035 14.4 0.1 6.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) PX PF00787.24 CEP18524.1 - 0.063 13.3 0.9 0.42 10.6 0.9 2.3 1 1 0 1 1 1 0 PX domain Pkinase PF00069.25 CEP18525.1 - 9.2e-54 182.6 0.0 1.2e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18525.1 - 9.1e-29 100.5 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP18525.1 - 4.2e-05 23.0 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP18525.1 - 0.0041 17.1 0.4 0.0064 16.5 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CEP18525.1 - 0.0052 16.2 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP18525.1 - 0.012 14.6 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP18525.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CEP18525.1 - 0.098 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FtsJ PF01728.19 CEP18526.1 - 1.3e-55 188.2 0.0 2.2e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase NTP_transf_2 PF01909.23 CEP18526.1 - 1.5e-12 47.6 0.0 5.5e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CEP18526.1 - 2.3e-09 37.3 1.4 4.4e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase Methyltransf_31 PF13847.6 CEP18526.1 - 0.00022 21.0 0.0 0.0034 17.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Polbeta PF18765.1 CEP18526.1 - 0.00091 19.3 0.0 0.0071 16.4 0.0 2.5 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DUF3467 PF11950.8 CEP18526.1 - 0.042 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) Methyltr_RsmB-F PF01189.17 CEP18526.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CEP18526.1 - 0.13 13.0 0.2 0.46 11.2 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 CEP18526.1 - 3.6 5.8 14.2 5.2 5.2 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RVT PF13966.6 CEP18527.1 - 2.1e-07 31.5 0.7 4.3e-07 30.5 0.7 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Troponin-I_N PF11636.8 CEP18528.1 - 0.078 12.9 0.5 0.12 12.3 0.5 1.3 1 0 0 1 1 1 0 Troponin I residues 1-32 RPN2_C PF18004.1 CEP18529.1 - 0.0056 16.6 2.7 0.008 16.1 2.7 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HTH_29 PF13551.6 CEP18529.1 - 0.0086 16.1 0.0 0.026 14.5 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CEP18529.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Ten1_2 PF15490.6 CEP18529.1 - 0.083 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DAO PF01266.24 CEP18531.1 - 3.1e-06 27.0 0.0 3.5e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CEP18531.1 - 0.0033 16.5 0.0 0.0043 16.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CEP18531.1 - 0.029 13.6 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LysM PF01476.20 CEP18532.1 - 0.0003 20.8 0.0 0.0009 19.3 0.0 1.8 1 0 0 1 1 1 1 LysM domain PGI PF00342.19 CEP18533.1 - 2.5e-255 847.6 0.9 3.7e-255 847.0 0.9 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.18 CEP18533.1 - 0.049 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF115 PI3_PI4_kinase PF00454.27 CEP18534.1 - 4e-33 115.3 0.0 8.7e-32 110.9 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CEP18534.1 - 1.3e-10 41.1 0.0 3.7e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CEP18534.1 - 0.00011 21.7 0.1 0.00025 20.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ISPD_C PF18706.1 CEP18534.1 - 0.0043 16.7 0.1 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF4135 PF13575.6 CEP18534.1 - 0.064 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Paramyxo_PNT PF14320.6 CEP18534.1 - 0.081 12.1 0.3 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 Phosphoprotein P region PNT disordered Auxin_repressed PF05564.12 CEP18534.1 - 3.9 8.2 7.7 1.2 9.8 2.9 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein RT_RNaseH_2 PF17919.1 CEP18535.1 - 2.6e-10 40.2 0.0 4.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP18535.1 - 4.4e-07 29.6 0.7 1.1e-06 28.4 0.7 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CEP18535.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DDE_3 PF13358.6 CEP18536.1 - 9.7e-22 77.3 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 CEP18536.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix RT_RNaseH PF17917.1 CEP18536.1 - 0.068 13.5 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CEP18537.1 - 2.2e-09 37.3 0.0 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP18537.1 - 0.0046 17.2 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP18537.1 - 0.046 13.6 0.3 0.099 12.6 0.3 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP18537.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Complex1_LYR PF05347.15 CEP18537.1 - 0.11 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) CLASP_N PF12348.8 CEP18537.1 - 0.17 11.4 0.3 0.41 10.2 0.2 1.6 1 1 1 2 2 2 0 CLASP N terminal Aldo_ket_red PF00248.21 CEP18540.1 - 0.00013 21.3 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4218 PF13960.6 CEP18541.1 - 0.018 14.7 1.4 0.028 14.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) RT_RNaseH PF17917.1 CEP18542.1 - 0.0071 16.6 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 CEP18547.1 - 0.11 12.5 0.5 0.11 12.5 0.5 2.1 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Zn_Tnp_IS1595 PF12760.7 CEP18548.1 - 0.51 10.4 8.8 0.87 9.6 0.9 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-LITAF-like PF10601.9 CEP18548.1 - 0.81 10.0 5.9 11 6.3 0.1 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Codanin-1_C PF15296.6 CEP18550.1 - 0.14 12.3 0.5 0.29 11.2 0.5 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus RT_RNaseH_2 PF17919.1 CEP18551.1 - 2.2e-29 101.4 0.1 6.5e-29 99.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP18551.1 - 3.3e-20 72.3 0.0 9.2e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CEP18551.1 - 2.7e-05 24.7 0.0 5.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Pepsin-I3 PF06394.13 CEP18551.1 - 0.0002 21.5 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain gag-asp_proteas PF13975.6 CEP18551.1 - 0.00044 20.7 0.0 0.00082 19.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP18551.1 - 0.02 14.7 0.2 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 CEP18551.1 - 0.044 13.6 0.2 0.076 12.8 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 CEP18551.1 - 0.062 13.1 0.5 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 Putative peptidase (DUF1758) AbiEi_1 PF09407.10 CEP18551.1 - 0.093 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain WYL_2 PF10902.8 CEP18552.1 - 0.031 14.6 0.3 0.046 14.1 0.3 1.3 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold DUF4301 PF14134.6 CEP18552.1 - 0.047 12.5 0.2 0.067 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Integrase_H2C2 PF17921.1 CEP18552.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain Bin3 PF06859.12 CEP18552.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) zf-Dof PF02701.15 CEP18553.1 - 0.015 15.5 1.6 0.029 14.5 0.3 2.2 2 0 0 2 2 2 0 Dof domain, zinc finger zinc_ribbon_12 PF11331.8 CEP18553.1 - 0.043 13.6 2.6 0.29 11.0 2.4 2.3 1 1 1 2 2 2 0 Probable zinc-ribbon domain LMBR1 PF04791.16 CEP18553.1 - 0.15 10.9 5.2 0.27 10.1 5.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein LIME1 PF15332.6 CEP18553.1 - 0.35 10.4 7.0 0.026 14.1 1.4 1.9 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 DUF3450 PF11932.8 CEP18553.1 - 0.54 9.5 9.7 1 8.6 9.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Thioredoxin_4 PF13462.6 CEP18553.1 - 1.4 9.1 7.6 1.2 9.3 4.7 2.2 2 0 0 2 2 2 0 Thioredoxin YabA PF06156.13 CEP18553.1 - 6.7 7.4 12.3 20 5.9 12.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA RVT_1 PF00078.27 CEP18554.1 - 9.3e-14 51.5 0.1 3.8e-13 49.5 0.0 2.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP18556.1 - 0.01 16.5 0.2 0.025 15.3 0.2 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RNB PF00773.19 CEP18558.1 - 9.8e-81 271.6 0.8 2.7e-80 270.2 0.3 2.0 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CEP18558.1 - 1.4e-20 73.1 0.0 3.2e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEP18558.1 - 1.5e-14 54.1 0.1 5.9e-14 52.2 0.1 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 CEP18558.1 - 0.0065 16.1 0.1 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain Amidase_3 PF01520.18 CEP18558.1 - 0.016 15.3 0.7 0.2 11.7 0.1 2.8 3 0 0 3 3 3 0 N-acetylmuramoyl-L-alanine amidase ASD2 PF08687.11 CEP18558.1 - 7.9 5.9 10.5 0.37 10.3 4.1 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Pathogen_betaC1 PF09593.10 CEP18559.1 - 0.043 13.7 0.1 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Beta-satellite pathogenicity beta C1 protein RWD PF05773.22 CEP18559.1 - 0.071 13.4 0.1 0.082 13.2 0.1 1.2 1 0 0 1 1 1 0 RWD domain Ribosomal_S3_C PF00189.20 CEP18560.1 - 3.3e-06 27.5 0.0 5.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain VAR1 PF05316.12 CEP18560.1 - 7.4e-06 25.2 2.8 0.0029 16.7 0.2 3.3 2 2 1 3 3 3 1 Mitochondrial ribosomal protein (VAR1) zf-CCHC_4 PF14392.6 CEP18562.1 - 0.0048 16.6 6.9 0.036 13.8 2.6 2.3 2 0 0 2 2 2 2 Zinc knuckle RskA PF10099.9 CEP18563.1 - 3.4e-06 27.5 6.7 0.00023 21.5 0.0 2.5 1 1 1 2 2 2 1 Anti-sigma-K factor rskA FOXP-CC PF16159.5 CEP18563.1 - 0.012 16.2 4.8 0.012 16.2 4.8 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain Nucleo_P87 PF07267.11 CEP18563.1 - 0.16 10.8 7.2 0.39 9.5 7.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-C2H2 PF00096.26 CEP18563.1 - 1.1 9.9 3.1 0.83 10.2 1.1 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Borrelia_P83 PF05262.11 CEP18563.1 - 1.2 7.5 7.3 2.2 6.7 7.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Adeno_PIX PF03955.14 CEP18563.1 - 1.7 8.8 13.4 0.12 12.6 2.4 2.6 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TFIIA PF03153.13 CEP18563.1 - 3.3 7.6 34.6 8.6 6.2 34.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CEP18563.1 - 4.6 5.9 8.5 8.9 5.0 8.5 1.5 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 CEP18563.1 - 5.1 7.1 8.1 18 5.3 2.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SCIMP PF15050.6 CEP18563.1 - 8.1 6.9 11.6 7.5 7.0 0.1 3.3 3 0 0 3 3 3 0 SCIMP protein zf-C3HC4_2 PF13923.6 CEP18564.1 - 0.0014 18.4 5.2 0.0014 18.4 5.2 4.0 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP18564.1 - 0.0022 18.3 5.6 0.0022 18.3 5.6 4.2 4 1 0 4 4 4 1 Ring finger domain IBR PF01485.21 CEP18564.1 - 0.0076 16.5 1.6 0.0076 16.5 1.6 4.7 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 CEP18564.1 - 0.016 15.1 4.8 0.016 15.1 4.8 4.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.11 CEP18565.1 - 0.057 11.5 3.7 0.063 11.4 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dickkopf_N PF04706.12 CEP18566.1 - 0.013 16.0 8.1 0.025 15.1 8.1 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MgrB PF13998.6 CEP18566.1 - 0.027 14.3 0.2 0.063 13.2 0.2 1.6 1 0 0 1 1 1 0 MgrB protein DUF4381 PF14316.6 CEP18566.1 - 0.028 14.7 0.2 0.042 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EB PF01683.18 CEP18566.1 - 0.033 14.5 8.0 0.062 13.6 8.0 1.4 1 0 0 1 1 1 0 EB module LMBR1 PF04791.16 CEP18566.1 - 0.093 11.6 0.9 0.13 11.1 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PspB PF06667.12 CEP18566.1 - 0.17 12.0 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Phage shock protein B MAP17 PF15807.5 CEP18566.1 - 0.17 12.1 0.8 0.37 11.0 0.8 1.7 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 XhlA PF10779.9 CEP18566.1 - 0.4 10.9 2.0 0.7 10.1 2.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA EGF PF00008.27 CEP18566.1 - 0.5 10.7 5.7 0.22 11.9 1.4 2.2 2 0 0 2 2 2 0 EGF-like domain GHMP_kinases_N PF00288.26 CEP18567.1 - 1.8e-11 44.1 0.1 4.3e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CEP18567.1 - 0.00015 22.1 0.0 0.00042 20.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal zf-RVT PF13966.6 CEP18569.1 - 1.3e-05 25.8 0.5 2.5e-05 24.9 0.5 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase KDZ PF18758.1 CEP18570.1 - 7.1e-10 38.9 0.1 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP18570.1 - 2.4e-06 27.6 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CRISPR_Cas2 PF09827.9 CEP18570.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 CRISPR associated protein Cas2 CxC1 PF18802.1 CEP18570.1 - 0.07 13.3 0.1 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases tRNA-synt_1 PF00133.22 CEP18571.1 - 2.1e-226 752.9 2.0 2.1e-226 752.9 2.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEP18571.1 - 6.3e-26 91.2 1.8 2e-25 89.5 0.0 2.6 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEP18571.1 - 8.2e-16 57.7 1.5 1.4e-07 30.6 0.1 4.5 3 2 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CEP18571.1 - 0.00019 20.9 0.1 0.0053 16.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain WD40 PF00400.32 CEP18572.1 - 1.5e-15 57.3 1.3 8.7e-05 23.2 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18572.1 - 7.4e-07 29.4 0.9 0.014 15.7 0.1 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Utp11 PF03998.13 CEP18573.1 - 7.1e-69 232.5 29.1 8.1e-69 232.3 29.1 1.0 1 0 0 1 1 1 1 Utp11 protein DUF4164 PF13747.6 CEP18573.1 - 0.0095 16.2 2.4 0.0095 16.2 2.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) PAS_10 PF13596.6 CEP18573.1 - 0.63 10.7 3.9 1.8 9.2 0.4 3.0 3 1 0 3 3 3 0 PAS domain RRN3 PF05327.11 CEP18573.1 - 0.76 8.2 6.5 0.97 7.9 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3808 PF10300.9 CEP18575.1 - 7.6e-68 229.4 5.8 1.5e-67 228.4 5.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 CEP18575.1 - 0.0044 17.0 0.5 1.4 9.2 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CEP18575.1 - 0.076 13.7 0.0 1.4 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 CEP18575.1 - 0.21 10.5 2.4 0.19 10.7 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 SR-25 PF10500.9 CEP18576.1 - 0.82 9.2 14.1 0.12 11.9 2.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tma16 PF11176.8 CEP18577.1 - 6.7e-43 146.1 5.2 8e-43 145.8 5.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Acyltransf_C PF16076.5 CEP18578.1 - 7.6e-18 64.4 1.0 2.4e-17 62.8 0.2 2.2 3 0 0 3 3 3 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CEP18578.1 - 7.4e-14 51.5 0.1 2.6e-12 46.5 0.1 2.4 1 1 0 1 1 1 1 Acyltransferase Rtt106 PF08512.12 CEP18579.1 - 9.8e-26 90.0 0.4 4e-25 88.0 0.0 2.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_18 PF18469.1 CEP18579.1 - 0.0053 16.7 0.5 0.018 15.0 0.5 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain NAD_binding_7 PF13241.6 CEP18580.1 - 3.2e-17 62.9 0.2 5e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CEP18580.1 - 7.3e-12 44.8 0.0 1.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CEP18580.1 - 8.1e-05 22.0 0.2 0.00016 21.0 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pdase_C33_assoc PF14756.6 CEP18580.1 - 0.021 14.8 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain NifU_N PF01592.16 CEP18580.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain START PF01852.19 CEP18581.1 - 2.1e-08 33.8 0.1 0.00073 19.0 0.1 2.9 2 0 0 2 2 2 2 START domain AhpC-TSA PF00578.21 CEP18582.1 - 1.2e-31 109.2 0.0 1.6e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CEP18582.1 - 3.7e-15 55.5 0.1 8.6e-15 54.3 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CEP18582.1 - 1.9e-12 47.2 0.0 2.5e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 CEP18582.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC CBS PF00571.28 CEP18583.1 - 1.3e-05 25.5 0.1 0.11 13.0 0.0 3.0 3 1 0 3 3 3 2 CBS domain BRE1 PF08647.11 CEP18584.1 - 1.4e-15 57.1 12.5 1.4e-15 57.1 12.5 7.6 6 2 2 9 9 9 1 BRE1 E3 ubiquitin ligase Sigma70_r4 PF04545.16 CEP18584.1 - 0.048 13.2 1.6 0.34 10.5 0.1 3.1 2 0 0 2 2 2 0 Sigma-70, region 4 Baculo_PEP_C PF04513.12 CEP18584.1 - 0.21 11.6 15.6 0.82 9.7 0.1 4.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_IE-1 PF05290.11 CEP18584.1 - 1.7 8.5 5.3 5.8 6.9 0.4 3.0 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) GvpG PF05120.12 CEP18584.1 - 3.7 7.6 8.8 0.42 10.7 0.5 3.7 3 0 0 3 3 3 0 Gas vesicle protein G UCR_14kD PF02271.16 CEP18585.1 - 5.4e-38 129.0 0.4 6.2e-38 128.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 CEP18585.1 - 0.0082 16.0 0.0 0.0086 15.9 0.0 1.0 1 0 0 1 1 1 1 She9 / Mdm33 family Dpoe2NT PF12213.8 CEP18586.1 - 0.058 13.7 0.0 0.087 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Helitron_like_N PF14214.6 CEP18587.1 - 5e-31 108.4 0.0 5.7e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LRR_6 PF13516.6 CEP18590.1 - 0.11 12.6 0.9 17 5.8 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 CEP18590.1 - 4.5 7.8 7.6 41 4.8 0.1 4.7 3 3 3 6 6 5 0 Leucine Rich repeats (2 copies) LIN37 PF15306.6 CEP18591.1 - 0.16 12.2 6.5 0.09 13.0 3.6 1.9 2 0 0 2 2 2 0 LIN37 RasGEF PF00617.19 CEP18592.1 - 5.1e-51 173.4 0.2 8.4e-51 172.7 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP18592.1 - 4e-12 46.3 2.7 5e-12 46.0 0.7 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 CEP18592.1 - 2e-06 27.5 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Response_reg PF00072.24 CEP18593.1 - 3.9e-21 75.3 0.3 1.9e-14 53.8 0.1 3.0 2 1 1 3 3 3 2 Response regulator receiver domain GET2 PF08690.10 CEP18594.1 - 0.03 14.0 2.1 0.045 13.4 2.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 PIF1 PF05970.14 CEP18596.1 - 5.2e-68 229.9 0.0 1.5e-45 156.0 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.14 CEP18596.1 - 0.0037 15.3 0.1 0.0054 14.7 0.1 1.1 1 0 0 1 1 1 1 Helicase XPC-binding PF09280.11 CEP18596.1 - 0.088 12.6 1.0 0.19 11.5 1.0 1.5 1 0 0 1 1 1 0 XPC-binding domain Fim-adh_lectin PF09222.10 CEP18597.1 - 2.1 7.8 5.8 0.52 9.8 2.7 1.6 1 1 1 2 2 2 0 Fimbrial adhesin F17-AG, lectin domain IF-2B PF01008.17 CEP18603.1 - 1.4e-64 218.0 3.0 4.5e-64 216.4 3.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family APG6 PF04111.12 CEP18604.1 - 1.8e-77 259.3 0.9 6.5e-77 257.5 0.0 2.1 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 CEP18604.1 - 1.1e-32 113.3 24.2 2.7e-32 112.1 24.2 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region BH3 PF15285.6 CEP18604.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting GOLGA2L5 PF15070.6 CEP18604.1 - 0.034 12.8 16.2 0.05 12.3 16.2 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 AAA_23 PF13476.6 CEP18604.1 - 3.6 8.0 10.7 8.3 6.9 10.7 1.6 1 0 0 1 1 1 0 AAA domain HD_3 PF13023.6 CEP18604.1 - 4.5 7.2 9.8 2.6 7.9 7.8 1.7 2 0 0 2 2 2 0 HD domain Seryl_tRNA_N PF02403.22 CEP18604.1 - 5.8 7.2 15.3 0.88 9.8 11.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EAP30 PF04157.16 CEP18605.1 - 6.5e-71 238.4 0.1 7.3e-71 238.2 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 CEP18605.1 - 0.018 14.9 1.1 0.037 13.9 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF2383 PF09537.10 CEP18605.1 - 0.078 13.3 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Exonuc_VII_L PF02601.15 CEP18605.1 - 0.092 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Endotoxin_N PF03945.14 CEP18605.1 - 0.1 12.3 0.1 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain ZapD PF07072.11 CEP18605.1 - 0.45 10.2 3.9 5 6.8 0.2 2.5 2 1 1 3 3 3 0 Cell division protein Mem_trans PF03547.18 CEP18606.1 - 1.8e-45 155.0 6.9 3.3e-45 154.1 6.9 1.4 1 1 0 1 1 1 1 Membrane transport protein G-alpha PF00503.20 CEP18607.1 - 3.5e-111 371.8 4.7 4e-111 371.6 4.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP18607.1 - 1.6e-12 47.3 3.0 1e-07 31.6 0.0 2.5 3 0 0 3 3 3 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 CEP18607.1 - 0.0007 19.0 0.2 0.0023 17.4 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 CEP18607.1 - 0.005 16.2 5.4 0.022 14.1 0.2 2.6 3 1 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP18607.1 - 0.045 14.0 0.5 3.8 7.7 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 CEP18607.1 - 0.072 12.2 0.4 0.15 11.2 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CEP18607.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PMT PF02366.18 CEP18608.1 - 1.9e-86 289.7 20.8 1.9e-86 289.7 20.8 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CEP18608.1 - 1.1e-61 207.9 16.7 1.1e-61 207.9 16.7 2.9 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CEP18608.1 - 1.1e-31 110.2 0.5 2.2e-31 109.2 0.5 1.4 1 0 0 1 1 1 1 MIR domain RVT_1 PF00078.27 CEP18609.1 - 4.2e-22 78.8 0.1 7.3e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP18609.1 - 1.6e-07 31.9 0.8 4.3e-07 30.6 0.8 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cation_efflux PF01545.21 CEP18610.1 - 9.5e-56 188.7 11.3 1.2e-55 188.4 11.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 CEP18610.1 - 0.0003 20.7 0.1 0.29 11.0 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5134) TMEM141 PF15110.6 CEP18610.1 - 0.012 16.2 1.3 0.18 12.4 0.1 2.8 3 0 0 3 3 3 0 TMEM141 protein family ETRAMP PF09716.10 CEP18610.1 - 0.8 9.8 6.1 0.57 10.3 0.4 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) FGGY_N PF00370.21 CEP18611.1 - 3.2e-69 233.2 0.0 4.7e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEP18611.1 - 2.2e-66 223.4 1.0 4.7e-66 222.3 0.6 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CEP18611.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family SBDS PF01172.18 CEP18612.1 - 2.2e-16 59.7 0.3 2.6e-16 59.5 0.3 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Transthyretin PF00576.21 CEP18613.1 - 7.5e-37 126.4 0.0 8.9e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Complex1_LYR PF05347.15 CEP18614.1 - 4.2e-13 49.1 1.0 6.3e-13 48.6 1.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CEP18614.1 - 0.00087 20.0 0.8 0.0012 19.5 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ANAPC15 PF15243.6 CEP18615.1 - 0.12 12.8 4.1 0.34 11.4 4.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Chromo PF00385.24 CEP18616.1 - 1.5e-12 47.2 4.4 1.5e-12 47.2 4.4 2.3 2 2 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CEP18616.1 - 1.3e-05 25.2 1.1 0.00069 19.7 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain CK_II_beta PF01214.18 CEP18617.1 - 3.7e-81 271.3 0.0 5.9e-81 270.6 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NTP_transferase PF00483.23 CEP18617.1 - 2.1e-28 99.6 0.0 3.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CEP18617.1 - 1.1e-09 37.7 10.3 3.1e-06 26.7 0.3 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CEP18617.1 - 6e-07 30.0 0.0 9.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CEP18617.1 - 0.02 14.6 1.5 0.32 10.8 1.0 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CEP18617.1 - 0.077 11.1 0.2 0.13 10.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CEP18617.1 - 0.11 11.4 0.2 0.27 10.1 0.1 1.7 2 0 0 2 2 2 0 L-fucokinase CxC5 PF18718.1 CEP18617.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases LIM PF00412.22 CEP18618.1 - 6.9e-32 109.5 52.7 2.7e-11 43.5 7.3 5.2 5 0 0 5 5 5 4 LIM domain Fer4_21 PF14697.6 CEP18618.1 - 0.035 14.2 0.8 0.035 14.2 0.8 4.4 5 1 1 6 6 6 0 4Fe-4S dicluster domain zf_UBZ PF18439.1 CEP18618.1 - 0.1 12.2 0.0 0.1 12.2 0.0 6.2 8 0 0 8 8 8 0 Ubiquitin-Binding Zinc Finger WRC PF08879.10 CEP18618.1 - 2.5 7.9 12.0 5.1 6.9 2.0 3.1 2 1 1 3 3 3 0 WRC Syntaxin PF00804.25 CEP18619.1 - 1.2e-32 113.2 14.5 1.2e-32 113.2 14.5 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CEP18619.1 - 4e-07 29.9 0.1 1.3e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CEP18619.1 - 1.2e-06 28.8 6.7 1.2e-06 28.8 6.7 2.8 2 1 1 3 3 3 1 Syntaxin-like protein Vac_Fusion PF02346.16 CEP18619.1 - 0.0042 16.7 1.0 0.0042 16.7 1.0 3.1 3 1 1 4 4 4 1 Chordopoxvirus multifunctional envelope protein A27 MCPsignal PF00015.21 CEP18619.1 - 0.01 15.7 3.0 0.01 15.7 3.0 3.1 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 CEP18619.1 - 0.014 15.2 3.6 0.014 15.2 3.6 2.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF4094 PF13334.6 CEP18619.1 - 0.051 14.0 0.4 0.051 14.0 0.4 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) YfdX PF10938.8 CEP18619.1 - 0.18 11.7 4.3 0.085 12.8 0.7 2.0 2 0 0 2 2 2 0 YfdX protein DUF724 PF05266.14 CEP18619.1 - 3.7 7.3 14.0 0.53 10.1 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) MAS20 PF02064.15 CEP18619.1 - 3.8 7.6 7.4 0.37 10.9 1.9 2.1 1 1 1 2 2 2 0 MAS20 protein import receptor DUF745 PF05335.13 CEP18619.1 - 3.8 7.2 8.7 0.14 11.8 0.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) PspA_IM30 PF04012.12 CEP18619.1 - 4.3 6.8 15.0 8.8 5.8 8.2 2.5 1 1 1 2 2 2 0 PspA/IM30 family SUI1 PF01253.22 CEP18620.1 - 1.3e-22 80.1 1.2 1.8e-22 79.6 0.4 1.7 1 1 1 2 2 2 1 Translation initiation factor SUI1 Acylphosphatase PF00708.18 CEP18620.1 - 0.054 13.9 0.4 0.054 13.9 0.4 2.1 1 1 1 2 2 2 0 Acylphosphatase DDE_3 PF13358.6 CEP18623.1 - 3.6e-17 62.5 0.0 4.2e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SOR_SNZ PF01680.17 CEP18624.1 - 5.9e-113 375.7 5.5 5.9e-113 375.7 5.5 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 CEP18624.1 - 2.5e-10 40.1 6.0 1.8e-07 30.8 0.3 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 CEP18624.1 - 6.5e-05 22.2 0.3 0.25 10.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 CEP18624.1 - 0.00056 19.2 0.2 0.13 11.5 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 CEP18624.1 - 0.013 15.5 0.0 0.046 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 CEP18624.1 - 0.018 14.5 0.4 0.44 10.0 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein NMO PF03060.15 CEP18624.1 - 0.036 13.4 3.7 0.36 10.2 0.1 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.21 CEP18624.1 - 0.041 13.1 0.1 0.61 9.2 0.0 2.6 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 CEP18624.1 - 0.063 12.9 0.1 0.92 9.1 0.0 2.2 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 CEP18624.1 - 0.069 12.5 0.6 1.9 7.8 0.1 2.7 2 1 0 2 2 2 0 Thiamine monophosphate synthase Y_phosphatase PF00102.27 CEP18626.1 - 3.8e-66 223.0 3.6 8.8e-66 221.8 3.6 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CEP18626.1 - 2.2e-12 47.4 0.0 6.4e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 CEP18626.1 - 0.028 14.2 0.1 0.091 12.6 0.1 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain NAD_binding_10 PF13460.6 CEP18629.1 - 2.5e-06 27.5 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP18629.1 - 1.3e-05 24.9 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Pro_sub2 PF18513.1 CEP18629.1 - 0.0073 16.5 0.5 0.027 14.6 0.1 2.2 2 0 0 2 2 2 1 Prodomain subtilisin 2 Ribosomal_S8 PF00410.19 CEP18630.1 - 1.1e-20 73.8 0.1 6.6e-20 71.4 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 MmcB-like PF06319.12 CEP18630.1 - 0.047 13.4 0.0 0.085 12.5 0.0 1.4 1 1 0 1 1 1 0 DNA repair protein MmcB-like LSM PF01423.22 CEP18631.1 - 2.8e-12 46.2 0.0 3.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Glucan_synthase PF02364.15 CEP18632.1 - 0 1161.0 9.8 5e-195 650.1 5.9 2.4 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CEP18632.1 - 8e-39 132.9 0.3 2.3e-38 131.4 0.3 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PrmA PF06325.13 CEP18633.1 - 1.7e-11 44.1 1.8 4.5e-11 42.7 0.1 2.3 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CEP18633.1 - 6.3e-11 42.8 0.1 4e-10 40.3 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18633.1 - 2.7e-10 40.2 2.7 3.7e-09 36.5 0.0 2.5 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP18633.1 - 8.4e-10 39.2 0.1 5.2e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CEP18633.1 - 1e-06 28.4 0.1 2.1e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2_2 PF12756.7 CEP18633.1 - 2.9e-06 27.6 2.3 9.5e-06 25.9 1.2 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Methyltransf_23 PF13489.6 CEP18633.1 - 2.1e-05 24.4 0.0 5.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP18633.1 - 4.5e-05 24.1 0.3 0.00044 21.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEP18633.1 - 5.3e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CEP18633.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 CEP18633.1 - 0.0026 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 CEP18633.1 - 0.0061 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_9 PF08003.11 CEP18633.1 - 0.014 14.4 0.3 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) UPF0020 PF01170.18 CEP18633.1 - 0.018 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 CEP18633.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5_C PF17286.2 CEP18633.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_24 PF13578.6 CEP18633.1 - 0.13 13.3 0.0 0.34 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol_E_B PF04042.16 CEP18634.1 - 9.8e-39 132.9 1.5 1.9e-38 132.0 1.5 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 CEP18634.1 - 1.3e-07 31.9 2.5 2.2e-07 31.1 2.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal LAMTOR PF15454.6 CEP18635.1 - 0.0067 17.0 2.2 0.0067 17.0 2.2 2.2 1 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PurL_C PF16904.5 CEP18635.1 - 0.064 13.6 0.3 0.16 12.3 0.1 1.7 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus NIF PF03031.18 CEP18637.1 - 6.8e-38 129.9 0.0 1e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase YjeF_N PF03853.15 CEP18638.1 - 1.8e-32 112.6 1.7 8.8e-32 110.3 0.0 2.4 2 0 0 2 2 2 1 YjeF-related protein N-terminus LSM PF01423.22 CEP18638.1 - 7.3e-05 22.4 0.5 0.00013 21.6 0.5 1.4 1 0 0 1 1 1 1 LSM domain ACR_tran PF00873.19 CEP18638.1 - 0.04 11.6 3.5 0.086 10.5 3.5 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Pep3_Vps18 PF05131.14 CEP18639.1 - 1e-47 161.7 0.5 2.1e-47 160.7 0.3 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CEP18639.1 - 1e-05 25.4 7.2 3.7e-05 23.6 1.2 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CEP18639.1 - 0.00033 21.1 2.5 0.0004 20.8 0.3 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CEP18639.1 - 0.003 17.1 1.6 0.003 17.1 1.6 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 CEP18639.1 - 0.0054 17.0 0.9 0.018 15.3 0.5 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 CEP18639.1 - 0.012 15.9 2.9 0.012 15.9 2.9 2.2 3 0 0 3 3 2 0 Ring finger domain TPR_8 PF13181.6 CEP18639.1 - 0.012 15.7 2.4 3.8 8.0 1.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 CEP18639.1 - 0.033 14.5 0.7 0.11 12.8 0.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CEP18639.1 - 0.073 12.8 6.9 0.34 10.7 6.9 2.3 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CEP18639.1 - 0.24 11.4 4.1 1.5 8.8 4.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain TPR_7 PF13176.6 CEP18639.1 - 0.24 11.5 2.7 26 5.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 CEP18639.1 - 0.25 11.4 1.4 0.72 9.9 1.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TPR_1 PF00515.28 CEP18639.1 - 0.3 11.0 9.0 2.3 8.2 2.9 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Zf_RING PF16744.5 CEP18639.1 - 0.35 11.0 4.8 0.15 12.2 1.4 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 CEP18639.1 - 0.65 9.9 9.8 0.062 13.2 4.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP18639.1 - 3.7 7.5 6.9 0.56 10.1 2.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RasGAP PF00616.19 CEP18640.1 - 3.8e-59 199.9 0.0 1.3e-58 198.1 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CEP18640.1 - 4.3e-38 130.6 0.1 4.3e-38 130.6 0.1 2.3 3 0 0 3 3 3 1 RasGAP C-terminus RNase_PH PF01138.21 CEP18640.1 - 5.5e-25 88.4 0.1 1.6e-24 86.9 0.1 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP18640.1 - 5.2e-06 26.4 0.0 1.6e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF4047 PF13256.6 CEP18640.1 - 0.014 15.6 0.3 0.061 13.5 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Herpes_UL14 PF03580.14 CEP18640.1 - 0.12 12.6 1.1 0.38 11.0 1.1 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Cob_adeno_trans PF01923.18 CEP18640.1 - 0.18 11.9 0.8 0.78 9.9 0.1 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF3800 PF12686.7 CEP18640.1 - 0.64 10.7 4.1 13 6.5 4.1 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) YabA PF06156.13 CEP18640.1 - 1.3 9.7 7.6 7.1 7.3 0.2 3.4 3 0 0 3 3 3 0 Initiation control protein YabA Big_7 PF17957.1 CEP18642.1 - 0.0033 18.2 1.0 0.014 16.1 1.0 1.9 1 1 0 1 1 1 1 Bacterial Ig domain NAR2 PF16974.5 CEP18642.1 - 0.016 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory UPF0172 PF03665.13 CEP18643.1 - 5.4e-50 170.1 0.0 6.4e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 CEP18643.1 - 0.00099 19.1 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEP18643.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Lectin_leg-like PF03388.13 CEP18644.1 - 8.5e-60 202.0 0.1 1.2e-59 201.5 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF1993 PF09351.10 CEP18644.1 - 0.0046 17.1 0.6 0.011 15.9 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) HAUS4 PF14735.6 CEP18644.1 - 0.014 15.1 1.9 0.014 15.1 1.9 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 SKA2 PF16740.5 CEP18644.1 - 0.05 13.4 9.4 0.026 14.3 3.7 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF16 PF01519.16 CEP18644.1 - 1 9.9 6.5 0.62 10.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 CEP18644.1 - 1.1 10.0 16.4 2.3 8.9 5.5 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mt_ATP-synt_D PF05873.12 CEP18644.1 - 1.2 9.0 5.9 7.3 6.4 0.3 2.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF948 PF06103.11 CEP18644.1 - 1.7 9.0 6.7 9.1 6.6 2.6 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CEP18644.1 - 1.9 8.8 8.3 0.2 12.0 2.6 2.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ARGLU PF15346.6 CEP18644.1 - 7.8 6.4 17.9 2.1 8.2 5.6 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 zf-C3HC4_3 PF13920.6 CEP18645.1 - 0.00057 19.7 8.5 0.00096 19.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CEP18645.1 - 1.3 9.3 8.3 1.1 9.5 5.2 2.3 2 1 0 2 2 2 0 B-box zinc finger Zn_ribbon_SprT PF17283.2 CEP18646.1 - 0.035 14.0 3.0 0.58 10.1 0.5 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF3818 PF12825.7 CEP18647.1 - 4e-85 285.8 10.4 9.7e-85 284.6 10.4 1.7 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CEP18647.1 - 9.2e-14 51.6 1.8 1.6e-12 47.5 1.8 2.7 1 1 0 1 1 1 1 PX-associated PX PF00787.24 CEP18647.1 - 5.6e-08 32.8 1.4 3.2e-07 30.3 1.4 2.4 1 1 0 1 1 1 1 PX domain CCDC24 PF15669.5 CEP18647.1 - 0.0026 17.7 4.1 1.1 9.0 0.0 3.3 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 24 family MAP7 PF05672.11 CEP18647.1 - 0.012 15.3 0.9 0.012 15.3 0.9 2.2 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family DUF4874 PF16173.5 CEP18647.1 - 0.061 13.0 1.1 4.6 6.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4874) bZIP_1 PF00170.21 CEP18647.1 - 0.23 11.6 10.5 0.022 14.8 4.0 2.6 2 0 0 2 2 2 0 bZIP transcription factor HTH_23 PF13384.6 CEP18648.1 - 2.6e-07 30.2 0.0 7.4e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CEP18648.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Myb_DNA-bind_6 PF13921.6 CEP18648.1 - 0.0093 16.2 0.3 0.024 14.9 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 CEP18648.1 - 0.022 14.8 1.3 0.041 14.0 1.3 1.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_Crp_2 PF13545.6 CEP18648.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain WD40 PF00400.32 CEP18649.1 - 0.00026 21.7 16.6 0.0011 19.8 0.0 5.4 3 2 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.15 CEP18649.1 - 0.0033 16.8 0.1 0.22 10.8 0.0 2.2 1 1 1 2 2 2 2 CPSF A subunit region Tetraspanin PF00335.20 CEP18650.1 - 3e-08 33.7 5.7 4.3e-08 33.2 5.7 1.2 1 0 0 1 1 1 1 Tetraspanin family Kei1 PF08552.11 CEP18650.1 - 0.031 14.2 3.6 0.041 13.8 0.1 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Pdase_C33_assoc PF14756.6 CEP18650.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase_C33-associated domain La PF05383.17 CEP18651.1 - 1.6e-21 76.1 0.0 4.5e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 La domain Cation_ATPase_C PF00689.21 CEP18652.1 - 1.2e-48 165.3 6.2 1.2e-48 165.3 6.2 1.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEP18652.1 - 2.2e-48 164.2 0.0 2.2e-48 164.2 0.0 3.6 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 CEP18652.1 - 7.9e-23 81.9 1.7 1.5e-21 77.7 1.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP18652.1 - 2.3e-15 56.0 0.0 4.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CEP18652.1 - 2.4e-14 53.2 0.0 5.1e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CEP18652.1 - 1.3e-05 25.1 3.6 0.0056 16.4 1.7 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP18652.1 - 0.0006 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 CEP18652.1 - 0.086 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Hydrolase_6 PF13344.6 CEP18652.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase adh_short PF00106.25 CEP18653.1 - 1.3e-32 112.8 0.2 3.3e-31 108.3 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP18653.1 - 4.2e-20 72.3 0.0 1.3e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP18653.1 - 1.8e-06 28.0 0.1 2.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_47 PF01532.20 CEP18654.1 - 1e-136 456.5 1.5 1.2e-136 456.3 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 CEP18654.1 - 0.013 14.0 0.0 2.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 DUF1713 PF08213.11 CEP18655.1 - 2.6e-14 52.8 20.5 3.9e-14 52.3 20.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ribosomal_S13 PF00416.22 CEP18656.1 - 1.7e-44 151.3 0.4 2e-44 151.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CEP18656.1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 CEP18656.1 - 0.021 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) adh_short PF00106.25 CEP18657.1 - 9.9e-21 74.1 0.0 2.3e-20 72.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP18657.1 - 2.9e-11 43.4 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CEP18657.1 - 3.6e-05 23.4 0.0 7.3e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CEP18657.1 - 7.8e-05 22.7 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEP18657.1 - 0.066 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CEP18657.1 - 0.12 11.7 0.3 0.19 11.1 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UDPGT PF00201.18 CEP18658.1 - 6.1e-25 88.0 0.0 1.9e-24 86.4 0.0 1.8 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEP18658.1 - 3.3e-10 40.2 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain GPCR_chapero_1 PF11904.8 CEP18658.1 - 0.037 13.5 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 GPCR-chaperone CLAMP PF14769.6 CEP18658.1 - 0.086 13.3 0.8 0.6 10.6 0.3 2.3 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 AdoHcyase PF05221.17 CEP18660.1 - 3.6e-132 440.0 0.0 2.5e-71 240.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CEP18660.1 - 2.2e-86 287.9 2.3 3.3e-86 287.3 2.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CEP18660.1 - 9.9e-10 38.1 0.1 2.2e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CEP18660.1 - 3.4e-05 23.5 0.1 5.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CEP18660.1 - 0.003 17.8 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.6 CEP18660.1 - 0.1 13.1 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein FG-GAP PF01839.23 CEP18661.1 - 5.8e-12 45.5 3.6 2.3e-05 24.4 0.4 4.6 5 0 0 5 5 5 2 FG-GAP repeat Zn_dep_PLPC PF00882.18 CEP18661.1 - 4.2e-11 43.2 1.6 1.1e-10 41.8 1.6 1.7 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 CEP18661.1 - 8.5e-06 26.3 0.8 0.00015 22.2 0.6 3.2 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 CEP18661.1 - 8.6e-06 25.9 0.0 0.00062 20.0 0.0 3.4 3 0 0 3 3 3 1 FG-GAP repeat zf-C2H2 PF00096.26 CEP18662.1 - 2.5e-08 33.9 11.4 8.2e-05 22.8 1.5 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP18662.1 - 4.4e-06 26.9 1.5 4.4e-06 26.9 1.5 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 CEP18662.1 - 0.025 14.9 2.3 0.025 14.9 2.3 3.6 3 1 1 4 4 4 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 CEP18662.1 - 0.4 11.3 8.7 0.23 12.1 0.6 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CEP18662.1 - 1 10.4 13.9 0.98 10.4 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.7 CEP18663.1 - 2e-33 114.8 26.2 9.8e-12 45.3 0.9 4.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP18663.1 - 3.5e-15 54.6 15.7 0.00066 19.9 0.0 9.1 8 2 2 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 CEP18663.1 - 5.7e-14 52.3 9.3 0.002 18.7 0.5 6.5 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 CEP18663.1 - 1.2e-09 38.2 15.9 0.046 14.2 0.4 8.7 6 2 2 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 CEP18663.1 - 3.7e-06 27.1 11.8 0.0034 17.7 0.2 6.3 5 3 3 8 8 8 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 CEP18663.1 - 7.7e-05 22.6 2.0 0.053 13.5 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) F-box-like_2 PF13013.6 CEP18663.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Phage_T7_Capsid PF05396.11 CEP18663.1 - 0.097 13.0 0.1 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Kei1 PF08552.11 CEP18664.1 - 3.8e-07 30.2 10.9 0.00053 19.9 0.1 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 SUR7 PF06687.12 CEP18664.1 - 0.00016 21.4 0.1 0.00018 21.2 0.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DHHC PF01529.20 CEP18664.1 - 0.026 14.6 3.4 0.035 14.2 3.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase OATP PF03137.20 CEP18664.1 - 0.079 11.2 0.6 0.12 10.6 0.1 1.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DNA_pol3_delta2 PF13177.6 CEP18665.1 - 1.9e-11 44.0 0.7 6.7e-11 42.2 0.7 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CEP18665.1 - 2.8e-07 30.6 0.2 5.1e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CEP18665.1 - 6.2e-07 29.9 0.1 1.4e-06 28.8 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CEP18665.1 - 0.00028 21.2 0.8 0.00065 20.1 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CEP18665.1 - 0.001 19.3 0.3 0.0039 17.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP18665.1 - 0.0024 18.3 1.7 0.029 14.7 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 CEP18665.1 - 0.0029 17.4 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CEP18665.1 - 0.011 15.5 0.7 0.026 14.3 0.2 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 CEP18665.1 - 0.046 13.1 0.0 0.35 10.2 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CEP18665.1 - 0.076 13.2 0.2 0.23 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CEP18665.1 - 0.13 12.1 2.7 0.95 9.3 0.9 2.4 1 1 1 2 2 2 0 Bacterial dnaA protein Phage_min_cap2 PF06152.11 CEP18665.1 - 0.46 9.3 3.2 1.3 7.9 3.0 1.8 1 1 0 1 1 1 0 Phage minor capsid protein 2 Peptidase_S8 PF00082.22 CEP18666.1 - 1e-44 153.0 1.1 1.6e-44 152.4 1.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CEP18666.1 - 8.1e-30 102.7 0.4 2e-29 101.4 0.4 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CEP18666.1 - 0.00025 21.8 0.0 0.0005 20.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Mito_carr PF00153.27 CEP18667.1 - 1.9e-26 91.8 2.4 1.7e-17 63.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PSP PF04046.16 CEP18668.1 - 3.1e-11 42.9 0.2 1e-10 41.3 0.2 1.9 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 CEP18668.1 - 0.0033 17.4 5.0 0.0033 17.4 5.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CEP18668.1 - 0.029 14.1 2.6 0.072 12.8 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle TFR_dimer PF04253.15 CEP18669.1 - 1.6e-29 102.4 0.1 3.5e-29 101.4 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CEP18669.1 - 2.9e-21 76.1 0.0 5.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CEP18669.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CEP18669.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CEP18669.1 - 0.18 11.2 0.1 0.81 9.1 0.0 2.0 3 0 0 3 3 3 0 Nicastrin Sugar_tr PF00083.24 CEP18672.1 - 7.2e-107 358.0 27.9 1.2e-104 350.8 27.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP18672.1 - 1.4e-25 90.0 27.5 1.4e-25 90.0 27.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Glug PF07581.12 CEP18672.1 - 0.34 11.4 2.3 1.6 9.3 2.3 2.2 1 0 0 1 1 1 0 The GLUG motif Sugar_tr PF00083.24 CEP18674.1 - 7e-107 358.1 27.9 1.1e-104 350.8 27.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CEP18674.1 - 8.8e-26 90.7 26.9 8.8e-26 90.7 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glug PF07581.12 CEP18674.1 - 0.33 11.5 2.3 1.6 9.3 2.3 2.2 1 0 0 1 1 1 0 The GLUG motif DEAD PF00270.29 CEP18675.1 - 2.2e-41 141.6 0.1 5.1e-41 140.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DNA_methylase PF00145.17 CEP18675.1 - 1.7e-36 126.3 0.1 4.4e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 CEP18675.1 - 1.3e-32 112.4 0.0 6.3e-32 110.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ima1_N PF09779.9 CEP18675.1 - 5.5e-15 56.4 0.3 5.5e-15 56.4 0.3 2.1 2 0 0 2 2 2 1 Ima1 N-terminal domain NYD-SP28_assoc PF14775.6 CEP18675.1 - 0.0034 17.5 0.1 0.0088 16.1 0.1 1.7 1 0 0 1 1 1 1 Sperm tail C-terminal domain AAA_19 PF13245.6 CEP18675.1 - 0.027 14.8 0.1 0.39 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CEP18675.1 - 0.11 12.8 0.1 0.41 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain Spt5_N PF11942.8 CEP18675.1 - 1.6 9.7 10.1 0.18 12.8 4.7 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal LRR_4 PF12799.7 CEP18676.1 - 6.5 7.3 15.3 4.2 7.9 0.1 3.7 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) EamA PF00892.20 CEP18677.1 - 2.1e-05 24.7 31.1 2.7e-05 24.4 7.6 2.5 2 1 1 3 3 3 2 EamA-like transporter family UPF0370 PF13980.6 CEP18677.1 - 0.072 13.1 0.6 4.4 7.4 0.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0370) SNO PF01174.19 CEP18678.1 - 6e-54 182.8 0.1 6.9e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CEP18678.1 - 4e-11 42.9 0.1 9e-11 41.7 0.1 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CEP18678.1 - 2.3e-05 24.2 0.2 5.2e-05 23.1 0.2 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 CEP18678.1 - 0.00051 19.7 0.0 0.00076 19.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 CEP18678.1 - 0.0024 17.7 0.1 0.0079 16.0 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 CEP18678.1 - 0.0081 15.9 1.8 6.8 6.4 0.1 3.0 2 1 0 2 2 2 2 Peptidase C26 UPF0052 PF01933.18 CEP18679.1 - 4.3e-44 150.9 0.0 9.9e-44 149.7 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0052 PI31_Prot_N PF11566.8 CEP18679.1 - 1.3e-43 148.7 0.0 2.3e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 CEP18679.1 - 1.1e-11 45.8 13.7 5.8e-11 43.4 13.7 2.3 1 0 0 1 1 1 1 PI31 proteasome regulator Piwi PF02171.17 CEP18682.1 - 1e-105 353.3 0.0 1.6e-105 352.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain E1-E2_ATPase PF00122.20 CEP18682.1 - 1.5e-32 112.6 0.0 1.5e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP18682.1 - 1.4e-30 106.3 18.3 1.2e-28 100.1 3.6 3.2 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus ArgoN PF16486.5 CEP18682.1 - 1.2e-27 97.2 0.0 2.7e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CEP18682.1 - 9.7e-20 70.0 0.0 2.5e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain Cation_ATPase PF13246.6 CEP18682.1 - 8.5e-18 64.2 0.0 1.9e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PAZ PF02170.22 CEP18682.1 - 1.2e-17 64.0 0.2 2.4e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 PAZ domain Hydrolase PF00702.26 CEP18682.1 - 4.2e-17 63.1 0.0 1.8e-16 61.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ArgoL2 PF16488.5 CEP18682.1 - 1.3e-10 41.4 0.4 3.6e-10 40.0 0.4 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CEP18682.1 - 4.3e-09 36.5 0.0 1.7e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute Cation_ATPase_N PF00690.26 CEP18682.1 - 4.5e-09 35.9 0.4 9.3e-08 31.7 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP18682.1 - 0.0013 18.5 0.4 0.0043 16.8 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Band_7_C PF16200.5 CEP18683.1 - 8.7e-27 93.0 3.2 2.4e-26 91.6 3.2 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7 PF01145.25 CEP18683.1 - 7.1e-20 71.8 2.9 1.3e-13 51.3 0.7 3.1 2 1 1 3 3 3 2 SPFH domain / Band 7 family Pox_A11 PF05061.13 CEP18683.1 - 0.072 12.4 1.6 0.74 9.0 1.6 2.1 1 1 0 1 1 1 0 Poxvirus A11 Protein DUF484 PF04340.12 CEP18683.1 - 1.2 8.8 7.0 3.3 7.3 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function, DUF484 Oxidored_FMN PF00724.20 CEP18684.1 - 4.9e-100 335.1 0.0 5.8e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Catalase PF00199.19 CEP18685.1 - 3.2e-201 668.4 0.3 3.9e-201 668.1 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CEP18685.1 - 9e-24 83.5 0.1 2.7e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Met_10 PF02475.16 CEP18686.1 - 4.2e-70 235.6 0.5 5.9e-70 235.1 0.5 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 CEP18686.1 - 0.00014 21.4 0.1 0.00077 18.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CEP18686.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 CEP18686.1 - 0.0026 17.0 0.2 0.003 16.8 0.2 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase AF0941-like PF14591.6 CEP18686.1 - 0.26 11.9 3.8 0.6 10.7 0.6 2.4 2 0 0 2 2 2 0 AF0941-like Zn_clus PF00172.18 CEP18687.1 - 2.7e-08 33.8 12.6 4.4e-08 33.1 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1336 PF07059.12 CEP18687.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) PIF PF05092.12 CEP18687.1 - 0.11 11.2 1.6 0.17 10.6 1.6 1.1 1 0 0 1 1 1 0 Per os infectivity Presenilin PF01080.17 CEP18688.1 - 6e-122 407.2 8.4 7.2e-122 407.0 8.4 1.1 1 0 0 1 1 1 1 Presenilin E1-E2_ATPase PF00122.20 CEP18689.1 - 1.1e-48 165.1 6.7 1.1e-48 165.1 6.7 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP18689.1 - 3.3e-32 111.7 5.2 3.3e-32 111.7 5.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CEP18689.1 - 1.4e-19 69.9 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP18689.1 - 9.4e-18 65.3 0.1 4e-16 59.9 0.0 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP18689.1 - 1e-16 60.3 0.5 2.4e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP18689.1 - 6.1e-05 22.9 0.5 0.0049 16.6 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ost5 PF05251.12 CEP18689.1 - 1.6 9.1 10.8 4.4 7.6 0.1 3.3 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 UPF0147 PF03685.13 CEP18690.1 - 0.28 11.3 2.1 0.57 10.3 0.1 2.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0147) PAP_assoc PF03828.19 CEP18692.1 - 9.6e-11 41.7 0.1 2.7e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF5416 PF17437.2 CEP18692.1 - 0.075 12.8 0.6 0.21 11.4 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5416) UAA PF08449.11 CEP18693.1 - 5e-97 324.8 14.6 6.4e-97 324.4 14.6 1.0 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CEP18693.1 - 7.7e-06 25.1 7.7 3.3e-05 23.0 1.4 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CEP18693.1 - 0.0012 19.0 27.5 0.33 11.1 7.2 3.4 2 2 0 2 2 2 2 EamA-like transporter family 2OG-FeII_Oxy_2 PF13532.6 CEP18694.1 - 1.2e-05 25.6 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrolase_6 PF13344.6 CEP18697.1 - 1.7e-11 44.1 0.0 4.6e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP18697.1 - 7.3e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CEP18697.1 - 0.00042 20.4 0.1 0.082 13.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP18697.1 - 0.0028 18.0 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CEP18697.1 - 0.079 12.6 0.1 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase zf-Tim10_DDP PF02953.15 CEP18698.1 - 1e-17 63.5 0.4 1.3e-17 63.2 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CEP18698.1 - 0.029 14.1 0.9 0.12 12.1 0.9 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Xan_ur_permease PF00860.20 CEP18699.1 - 3.1e-25 88.7 31.0 6.2e-24 84.4 29.1 2.7 2 1 0 2 2 2 1 Permease family Herpes_Helicase PF02689.14 CEP18699.1 - 0.032 12.2 0.1 0.049 11.6 0.1 1.2 1 0 0 1 1 1 0 Helicase GxDLY PF14607.6 CEP18700.1 - 0.024 14.5 1.7 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type FHA PF00498.26 CEP18701.1 - 7.2e-14 51.9 0.0 1.6e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain G-patch PF01585.23 CEP18701.1 - 9.9e-13 47.8 1.7 3e-11 43.0 2.3 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CEP18701.1 - 1.9e-08 34.3 0.0 5.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 CEP18701.1 - 1.4e-06 28.5 0.0 3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain OCRE PF17780.1 CEP18701.1 - 0.00019 21.4 4.8 0.0043 17.1 3.7 3.0 3 0 0 3 3 3 1 OCRE domain PQ-loop PF04193.14 CEP18702.1 - 6.9e-17 61.0 10.2 1.9e-12 46.7 3.8 2.9 2 1 1 3 3 3 2 PQ loop repeat Peptidase_U4 PF03419.13 CEP18702.1 - 0.0045 16.3 7.7 0.0088 15.4 7.7 1.5 1 1 0 1 1 1 1 Sporulation factor SpoIIGA Ribosomal_S8e PF01201.22 CEP18703.1 - 1.3e-55 187.3 0.6 1.5e-55 187.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Abhydrolase_1 PF00561.20 CEP18704.1 - 8.9e-19 68.1 0.1 1.2e-16 61.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CEP18704.1 - 6.1e-18 64.2 0.5 1.6e-17 62.8 0.5 1.8 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CEP18704.1 - 9.2e-06 25.1 0.0 0.011 15.0 0.0 2.6 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Methyltrn_RNA_4 PF09936.9 CEP18704.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase FSH1 PF03959.13 CEP18704.1 - 0.17 11.5 0.4 18 4.9 0.0 2.6 3 1 0 3 3 3 0 Serine hydrolase (FSH1) Bap31 PF05529.12 CEP18705.1 - 7.6e-39 132.7 0.9 1.3e-38 131.9 0.9 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CEP18705.1 - 3.7e-11 42.9 8.3 3.7e-11 42.9 8.3 2.2 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain PHR PF08005.12 CEP18705.1 - 0.042 14.5 0.1 0.062 14.0 0.1 1.3 1 0 0 1 1 1 0 PHR domain AhpC-TSA PF00578.21 CEP18705.1 - 0.079 12.9 0.5 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF2987 PF11205.8 CEP18705.1 - 0.082 12.8 3.9 0.13 12.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) FAM76 PF16046.5 CEP18705.1 - 0.86 8.9 10.2 0.5 9.7 7.8 1.7 1 1 1 2 2 2 0 FAM76 protein Jnk-SapK_ap_N PF09744.9 CEP18705.1 - 1.7 8.8 17.5 0.55 10.4 14.9 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Nucleoporin_FG2 PF15967.5 CEP18705.1 - 3.4 6.1 4.2 4.1 5.8 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region HOIP-UBA PF16678.5 CEP18706.1 - 0.019 14.9 0.4 0.021 14.8 0.4 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair DLEU7 PF15760.5 CEP18706.1 - 0.03 13.8 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Leukemia-associated protein 7 Dcc1 PF09724.9 CEP18706.1 - 0.033 13.5 0.8 0.035 13.4 0.8 1.0 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 DUF1068 PF06364.12 CEP18706.1 - 0.12 12.3 2.0 0.17 11.8 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) Longin PF13774.6 CEP18707.1 - 2.6e-29 101.1 0.1 3.9e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CEP18707.1 - 5.8e-14 51.7 0.0 8.2e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Matrilin_ccoil PF10393.9 CEP18707.1 - 0.047 13.6 0.3 0.13 12.1 0.3 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MCD PF05292.11 CEP18708.1 - 5.6e-81 271.9 0.0 1.6e-80 270.4 0.0 1.7 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 CEP18708.1 - 1.1e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain HTH_30 PF13556.6 CEP18709.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RabGAP-TBC PF00566.18 CEP18710.1 - 1.1e-38 133.0 0.3 2.9e-38 131.7 0.3 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MBF1 PF08523.10 CEP18711.1 - 1e-23 83.5 3.2 1.9e-23 82.7 3.2 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CEP18711.1 - 1e-09 38.3 0.4 2.1e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix PLA2_B PF01735.18 CEP18713.1 - 5.7e-29 100.9 2.0 1.3e-18 66.7 0.5 3.5 3 1 0 3 3 3 2 Lysophospholipase catalytic domain Mst1_SARAH PF11629.8 CEP18713.1 - 0.013 15.6 0.2 0.057 13.5 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1454 PF07305.12 CEP18713.1 - 0.063 12.7 0.3 0.31 10.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1454) Colicin_V PF02674.16 CEP18713.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Colicin V production protein Rod-binding PF10135.9 CEP18714.1 - 0.18 12.4 0.0 0.27 11.9 0.0 1.2 1 0 0 1 1 1 0 Rod binding protein Beach PF02138.18 CEP18715.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Beige/BEACH domain Cwf_Cwc_15 PF04889.12 CEP18715.1 - 6.1 6.5 6.5 11 5.7 6.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Coa1 PF08695.10 CEP18717.1 - 2.1e-25 88.7 0.2 2.7e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MacB_PCD PF12704.7 CEP18717.1 - 0.11 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain Abhydrolase_2 PF02230.16 CEP18719.1 - 3.1e-55 187.3 0.0 3.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 CEP18719.1 - 1e-06 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CEP18719.1 - 3.6e-06 26.4 0.4 0.0063 15.8 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CEP18719.1 - 4.3e-06 26.6 0.0 7.4e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CEP18719.1 - 0.00011 21.7 0.0 0.00029 20.4 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CEP18719.1 - 0.0052 16.7 0.1 1.5 8.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.8 CEP18719.1 - 0.0073 15.5 0.0 0.041 13.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 CEP18719.1 - 0.0075 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 CEP18719.1 - 0.0092 16.6 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 CEP18720.1 - 1.8e-33 115.9 39.2 1.8e-33 115.9 39.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP18720.1 - 3.3e-05 22.9 33.1 0.00037 19.5 8.6 2.4 1 1 0 2 2 2 2 Sugar (and other) transporter Elong_Iki1 PF10483.9 CEP18721.1 - 1.4e-52 179.1 0.1 1.7e-52 178.8 0.1 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 GSHPx PF00255.19 CEP18722.1 - 1.3e-10 40.8 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase DUF962 PF06127.11 CEP18723.1 - 7.9e-22 77.2 3.5 2e-21 75.9 3.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Peptidase_S9 PF00326.21 CEP18723.1 - 1.4e-07 31.2 0.1 8.2e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2048 PF09752.9 CEP18723.1 - 0.0057 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 FSH1 PF03959.13 CEP18723.1 - 0.0059 16.3 0.0 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CEP18723.1 - 0.014 15.0 0.0 0.046 13.3 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family RICTOR_N PF14664.6 CEP18724.1 - 1.1e-85 287.9 1.2 4.2e-85 286.0 0.6 2.2 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 CEP18724.1 - 7.7e-39 132.4 0.2 8.7e-37 125.8 0.1 3.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 CEP18724.1 - 2.2e-38 130.2 0.8 1.9e-33 114.3 0.1 5.3 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CEP18724.1 - 4.6e-27 94.1 7.1 3e-16 59.4 0.0 6.4 6 2 1 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 CEP18724.1 - 5.1e-07 29.7 4.8 2.1e-06 27.7 4.8 2.1 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.23 CEP18724.1 - 0.00095 19.1 10.0 2.8 8.1 0.0 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP18724.1 - 0.0011 19.3 3.6 2.3 8.7 0.1 5.0 5 1 0 5 5 4 1 HEAT repeats Adaptin_N PF01602.20 CEP18724.1 - 0.0017 17.0 3.0 0.64 8.5 0.0 3.6 3 1 0 3 3 3 1 Adaptin N terminal region RasGAP_C PF03836.15 CEP18724.1 - 0.048 13.8 1.2 0.12 12.5 1.2 1.6 1 0 0 1 1 1 0 RasGAP C-terminus CREPT PF16566.5 CEP18724.1 - 0.057 13.6 2.0 0.17 12.1 2.0 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CAMSAP_CC1 PF17095.5 CEP18724.1 - 0.11 12.4 2.7 0.28 11.1 2.7 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF5344 PF17279.2 CEP18724.1 - 0.22 12.1 5.2 0.54 10.9 1.7 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5344) HEAT PF02985.22 CEP18724.1 - 0.23 11.8 0.8 69 4.1 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat AAA_23 PF13476.6 CEP18724.1 - 3.2 8.2 6.6 6.9 7.1 6.6 1.5 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.20 CEP18725.1 - 6.7e-135 449.5 0.0 7.6e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEP18725.1 - 3.5e-06 26.2 0.0 5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CEP18725.1 - 3.5e-05 23.2 0.0 5.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 CEP18725.1 - 0.00056 18.6 0.0 0.0037 15.9 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.13 CEP18725.1 - 0.015 14.3 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 CEP18725.1 - 0.037 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Galactosyl_T PF01762.21 CEP18726.1 - 2.9e-21 76.2 0.0 4.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.8 CEP18726.1 - 3e-10 40.3 12.1 4.4e-10 39.8 11.6 1.5 1 1 0 1 1 1 1 N-glycosylation protein Gly_transf_sug PF04488.15 CEP18726.1 - 1.7e-08 35.0 0.2 4.7e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 CEP18726.1 - 3.9e-05 23.9 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.12 CEP18726.1 - 0.0018 17.7 0.4 0.0035 16.8 0.4 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 CEP18726.1 - 0.089 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_21 PF13506.6 CEP18726.1 - 0.097 12.1 0.1 0.21 11.0 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF4173 PF13777.6 CEP18726.1 - 0.26 10.7 9.3 0.11 11.9 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) GDI PF00996.18 CEP18727.1 - 2.8e-161 536.9 0.4 1.9e-144 481.4 0.1 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor Usp PF00582.26 CEP18728.1 - 1.5e-21 77.4 0.0 5.1e-21 75.7 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family Metallophos PF00149.28 CEP18730.1 - 1.3e-13 51.9 0.4 1.7e-13 51.6 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 CEP18730.1 - 0.00072 18.0 0.0 0.004 15.5 0.0 2.0 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Not1 PF04054.15 CEP18731.1 - 3.4e-117 391.4 0.1 1.6e-116 389.3 0.0 2.2 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CEP18731.1 - 2e-89 298.9 0.5 2e-89 298.9 0.5 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CEP18731.1 - 2.4e-56 189.9 0.1 2.4e-56 189.9 0.1 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CEP18731.1 - 8.1e-39 132.9 1.7 2.4e-38 131.4 1.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CEP18731.1 - 8.9e-36 123.2 0.3 8.9e-36 123.2 0.3 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TFIIA PF03153.13 CEP18731.1 - 0.86 9.5 6.9 1.8 8.5 6.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FKBP_C PF00254.28 CEP18732.1 - 3.3e-33 113.9 0.0 3.7e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AA_permease_2 PF13520.6 CEP18733.1 - 2.5e-44 151.8 42.3 3.1e-44 151.5 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cyclin_N PF00134.23 CEP18734.1 - 2.4e-11 43.4 0.1 4.2e-09 36.2 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CEP18734.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain DUF4448 PF14610.6 CEP18735.1 - 0.0021 17.9 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) Trp_oprn_chp PF09534.10 CEP18735.1 - 0.023 14.5 0.6 0.055 13.3 0.0 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5305 PF17231.2 CEP18735.1 - 0.043 13.2 0.0 0.043 13.2 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 CEP18735.1 - 0.046 13.7 0.3 0.046 13.7 0.3 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Insulin_TMD PF17870.1 CEP18735.1 - 0.18 11.9 0.2 0.34 11.0 0.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 CEP18735.1 - 1 9.7 5.0 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Orf78 (ac78) Goodbye PF17109.5 CEP18735.1 - 1 9.8 5.0 2.6 8.5 0.1 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Podoplanin PF05808.11 CEP18735.1 - 1.3 9.1 11.3 1.9 8.6 0.0 3.3 3 0 0 3 3 3 0 Podoplanin bZIP_2 PF07716.15 CEP18736.1 - 5.4e-12 45.6 16.0 5.4e-12 45.6 16.0 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP18736.1 - 1.8e-11 44.0 14.7 1.8e-11 44.0 14.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 CEP18736.1 - 5.9e-07 29.9 8.6 5.9e-07 29.9 8.6 2.6 2 0 0 2 2 2 1 bZIP Maf transcription factor ATF7IP_BD PF16788.5 CEP18736.1 - 0.00018 21.7 15.5 0.00018 21.7 15.5 3.3 2 2 1 3 3 3 1 ATF-interacting protein binding domain HOOK PF05622.12 CEP18736.1 - 0.00037 18.8 5.2 0.00037 18.8 5.2 1.6 2 0 0 2 2 2 1 HOOK protein TMCO5 PF14992.6 CEP18736.1 - 0.00063 19.4 5.0 0.00063 19.4 5.0 1.7 2 0 0 2 2 2 1 TMCO5 family CCD48 PF15799.5 CEP18736.1 - 0.0032 15.9 2.3 0.0032 15.9 2.3 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 48 YabA PF06156.13 CEP18736.1 - 0.009 16.6 0.7 0.009 16.6 0.7 2.3 2 0 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 CEP18736.1 - 0.0094 15.7 4.8 0.0094 15.7 4.8 2.7 2 0 0 2 2 2 1 Septum formation initiator HALZ PF02183.18 CEP18736.1 - 0.012 15.8 6.8 0.26 11.5 3.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CEP18736.1 - 0.018 15.2 1.7 0.018 15.2 1.7 2.3 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1192 PF06698.11 CEP18736.1 - 0.086 12.9 3.1 1.3 9.1 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Spc24 PF08286.11 CEP18736.1 - 0.28 11.4 6.4 0.1 12.9 0.8 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TSC22 PF01166.18 CEP18736.1 - 0.29 11.5 6.2 0.066 13.5 2.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Nnf1 PF03980.14 CEP18736.1 - 0.36 11.2 15.3 0.27 11.6 7.1 3.0 2 0 0 2 2 2 0 Nnf1 ABC_tran_CTD PF16326.5 CEP18736.1 - 3.1 8.1 12.4 2.7 8.3 7.7 2.8 2 1 0 2 2 1 0 ABC transporter C-terminal domain TMA7 PF09072.10 CEP18736.1 - 5.2 8.0 8.4 0.34 11.8 2.1 2.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 O-FucT PF10250.9 CEP18737.1 - 7.6e-12 45.6 2.2 1.5e-11 44.6 2.2 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HLH PF00010.26 CEP18738.1 - 1.4e-11 44.1 0.4 2.4e-11 43.4 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SURF2 PF05477.11 CEP18738.1 - 0.023 14.4 3.0 0.032 13.9 3.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) F-box-like PF12937.7 CEP18741.1 - 2.1e-12 46.7 1.5 6e-12 45.3 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP18741.1 - 1.9e-06 27.6 2.7 5.5e-06 26.1 2.7 1.9 1 0 0 1 1 1 1 F-box domain Methyltransf_25 PF13649.6 CEP18741.1 - 0.0014 19.3 0.0 0.0038 17.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEP18741.1 - 0.0048 16.7 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CEP18741.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CEP18741.1 - 0.043 13.3 0.1 0.16 11.5 0.0 1.9 3 0 0 3 3 3 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 CEP18741.1 - 0.14 13.0 0.0 0.41 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HMA PF00403.26 CEP18742.1 - 1.6e-56 188.6 7.3 1.4e-15 57.5 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CEP18742.1 - 7.9e-44 149.3 1.4 7.9e-44 149.3 1.4 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CEP18742.1 - 1.2e-37 130.2 0.1 2.4e-37 129.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 CEP18742.1 - 0.00021 21.3 0.0 0.54 10.3 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif Hydrolase_3 PF08282.12 CEP18742.1 - 0.0016 18.2 1.2 0.0087 15.8 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 CEP18742.1 - 0.14 12.5 10.0 43 4.6 0.1 5.2 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain DUF2013 PF09431.10 CEP18744.1 - 1e-26 93.8 4.7 1.9e-19 70.2 0.9 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2013) FTA4 PF13093.6 CEP18744.1 - 0.015 15.2 0.2 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NBD94 PF16830.5 CEP18744.1 - 0.043 14.2 0.3 1.5 9.3 0.1 2.7 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Cyt-b5 PF00173.28 CEP18745.1 - 5.1e-09 36.1 0.6 8.4e-09 35.5 0.6 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATG27 PF09451.10 CEP18745.1 - 0.056 13.3 0.3 0.078 12.8 0.3 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF5065 PF16723.5 CEP18746.1 - 0.16 12.0 1.0 0.42 10.7 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) Rx_N PF18052.1 CEP18746.1 - 0.34 11.2 2.3 13 6.2 2.4 2.7 2 0 0 2 2 2 0 Rx N-terminal domain MAP65_ASE1 PF03999.12 CEP18746.1 - 3.2 6.3 24.0 0.043 12.5 11.2 2.1 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.25 CEP18747.1 - 5.1e-50 170.3 0.0 8.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18747.1 - 2.8e-38 131.7 0.0 4.1e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP18747.1 - 0.00012 21.0 0.0 0.00012 21.0 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEP18747.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like UQ_con PF00179.26 CEP18748.1 - 2.7e-40 137.3 0.0 3.8e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_46 PF01374.18 CEP18749.1 - 2.8e-32 112.1 0.0 4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Opy2 PF09463.10 CEP18749.1 - 0.0051 17.1 6.1 0.0051 17.1 6.1 8.5 7 3 0 7 7 7 2 Opy2 protein Inhibitor_I36 PF03995.13 CEP18750.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor family I36 Retrotrans_gag PF03732.17 CEP18750.1 - 0.018 15.3 1.5 0.032 14.5 0.7 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein F-actin_cap_A PF01267.17 CEP18751.1 - 1e-98 330.0 1.2 1.2e-98 329.8 1.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Vps51 PF08700.11 CEP18751.1 - 0.072 13.2 1.4 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 Vps51/Vps67 CCP_MauG PF03150.14 CEP18751.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.5 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase Arrestin_C PF02752.22 CEP18752.1 - 7.1e-06 26.5 2.1 9.4e-06 26.1 0.8 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 CEP18752.1 - 0.036 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Methyltransf_15 PF09445.10 CEP18753.1 - 1.9e-43 147.9 0.0 3.6e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CEP18753.1 - 4.1e-07 29.9 0.0 3.5e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 CEP18753.1 - 8.9e-07 29.5 0.2 3.2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CEP18753.1 - 1.5e-05 24.9 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CEP18753.1 - 0.0001 22.0 0.2 0.00041 20.1 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 CEP18753.1 - 0.0012 18.3 4.5 0.0035 16.8 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CEP18753.1 - 0.0026 18.4 0.0 0.0074 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEP18753.1 - 0.0083 16.1 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Sec3_C_2 PF15278.6 CEP18753.1 - 1.9 8.9 8.6 0.1 12.9 1.3 2.9 3 0 0 3 3 3 0 Sec3 exocyst complex subunit ThrE PF06738.12 CEP18754.1 - 8.8e-47 159.5 17.1 6e-43 146.9 0.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CEP18754.1 - 2.3e-05 24.6 10.8 2.3e-05 24.6 10.8 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE CheC PF04509.12 CEP18754.1 - 0.62 10.0 5.4 0.082 12.8 0.8 1.9 2 0 0 2 2 2 0 CheC-like family Carboxyl_trans PF01039.22 CEP18755.1 - 2e-114 383.0 0.0 2.5e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Methyltransf_25 PF13649.6 CEP18757.1 - 6.2e-12 46.1 0.0 5.9e-11 42.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP18757.1 - 3.3e-10 40.0 0.0 8.8e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP18757.1 - 3.8e-10 40.3 0.0 1.3e-09 38.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP18757.1 - 3.4e-08 33.4 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEP18757.1 - 0.0012 19.5 0.0 0.0056 17.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP18757.1 - 0.023 14.0 0.0 0.13 11.6 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CEP18757.1 - 0.024 14.1 0.0 0.061 12.8 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase DUF1765 PF08578.10 CEP18758.1 - 0.045 14.2 7.7 0.25 11.8 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1765) MetOD1 PF18546.1 CEP18758.1 - 0.088 12.8 0.2 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Metanogen output domain 1 UNC45-central PF11701.8 CEP18758.1 - 1.8 8.5 6.5 1.6 8.7 0.1 4.0 4 1 2 6 6 6 0 Myosin-binding striated muscle assembly central ubiquitin PF00240.23 CEP18759.1 - 0.0035 17.0 0.1 0.0048 16.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP18759.1 - 0.013 15.3 0.1 0.013 15.3 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like EIIA-man PF03610.16 CEP18759.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 PTS system fructose IIA component DUF2407 PF10302.9 CEP18759.1 - 0.065 13.8 0.0 0.075 13.6 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RVP_2 PF08284.11 CEP18761.1 - 0.0021 17.8 0.1 0.0044 16.8 0.1 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease T7SS_ESX_EspC PF10824.8 CEP18762.1 - 0.057 13.9 0.1 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm CTU2 PF10288.9 CEP18762.1 - 1.1 9.5 8.8 2.2 8.6 0.9 3.2 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 PRKCSH-like PF12999.7 CEP18764.1 - 6.3e-56 188.9 12.9 1.2e-55 188.0 7.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CEP18764.1 - 8.5e-32 110.0 2.0 9.9e-32 109.8 0.9 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CEP18764.1 - 2.7e-06 28.3 1.0 2.7e-06 28.3 1.0 2.9 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein TPR_MLP1_2 PF07926.12 CEP18764.1 - 0.015 15.3 11.1 0.24 11.5 4.5 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.13 CEP18764.1 - 0.027 14.2 4.6 0.098 12.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Ldl_recept_a PF00057.18 CEP18764.1 - 0.04 14.1 2.1 0.04 14.1 2.1 3.6 2 1 1 3 3 2 0 Low-density lipoprotein receptor domain class A Spc7 PF08317.11 CEP18764.1 - 0.043 12.7 11.2 1.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.12 CEP18764.1 - 0.52 10.6 8.7 2 8.7 6.0 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) RRN3 PF05327.11 CEP18764.1 - 0.7 8.4 9.5 1 7.8 9.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FlaC_arch PF05377.11 CEP18764.1 - 0.72 10.3 3.0 9.6 6.7 0.2 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 CEP18764.1 - 2.8 8.3 8.8 0.6 10.4 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF349 PF03993.12 CEP18764.1 - 5.1 7.5 10.1 3.9 7.8 3.7 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) KDZ PF18758.1 CEP18765.1 - 4.2e-33 114.8 2.1 4.2e-33 114.8 2.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CEP18765.1 - 0.075 13.2 0.2 0.27 11.4 0.2 2.0 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Hypoth_Ymh PF09509.10 CEP18765.1 - 0.1 12.5 0.5 0.28 11.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Mei5_like PF17021.5 CEP18765.1 - 0.29 11.2 5.7 0.76 9.8 1.3 2.8 2 0 0 2 2 2 0 Putative double-strand recombination repair-like RRM_1 PF00076.22 CEP18767.1 - 2.3e-15 56.2 0.0 3.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CEP18767.1 - 5.7e-06 26.8 2.4 5.7e-06 26.8 2.4 2.8 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.6 CEP18767.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CEP18767.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain VacA2 PF03077.14 CEP18767.1 - 0.054 13.4 0.8 3.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Putative vacuolating cytotoxin SH3_1 PF00018.28 CEP18768.1 - 2.1e-09 36.8 0.0 4.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP18768.1 - 7.4e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP18768.1 - 7.8e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex26 PF07163.12 CEP18769.1 - 0.019 14.3 0.1 0.019 14.3 0.1 1.6 2 0 0 2 2 2 0 Pex26 protein LAP1C PF05609.12 CEP18769.1 - 0.068 12.3 8.8 0.087 11.9 8.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EMC3_TMCO1 PF01956.16 CEP18769.1 - 0.13 12.0 0.1 3.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like GREB1 PF15782.5 CEP18769.1 - 0.47 7.5 8.9 0.55 7.3 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer U1snRNP70_N PF12220.8 CEP18769.1 - 0.65 10.7 5.2 1.7 9.4 0.5 2.7 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pex14_N PF04695.13 CEP18769.1 - 2.2 8.9 15.2 0.037 14.7 2.2 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Orf78 PF06024.12 CEP18769.1 - 2.7 8.4 10.5 2.1 8.7 3.5 3.0 2 1 0 2 2 2 0 Orf78 (ac78) EAF PF09816.9 CEP18770.1 - 5e-06 26.8 3.7 2.9e-05 24.4 3.7 2.2 1 1 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF4767 PF15983.5 CEP18770.1 - 0.077 13.3 0.8 0.18 12.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) DUF5114 PF17141.4 CEP18770.1 - 0.11 13.0 0.9 0.32 11.6 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5114) Zip PF02535.22 CEP18771.1 - 1.6e-57 195.2 14.4 2.5e-56 191.3 14.4 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter UPF0113 PF03657.13 CEP18771.1 - 0.054 13.8 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 UPF0113 PUA domain SSPI PF14098.6 CEP18771.1 - 0.91 9.7 2.9 36 4.6 0.1 2.9 2 1 0 2 2 2 0 Small, acid-soluble spore protein I SWIB PF02201.18 CEP18772.1 - 8.8e-18 64.0 0.1 1.8e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Cyclase PF04199.13 CEP18772.1 - 3e-15 56.7 0.0 1e-14 54.9 0.0 1.8 2 0 0 2 2 2 1 Putative cyclase DEK_C PF08766.11 CEP18772.1 - 3.5e-12 46.1 0.4 7.3e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain TSP9 PF11493.8 CEP18772.1 - 0.22 12.2 1.1 0.43 11.3 1.1 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 DNA_pol_B PF00136.21 CEP18773.1 - 1.2e-99 334.1 0.0 2.1e-99 333.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CEP18773.1 - 2.4e-20 72.9 3.2 2.2e-09 36.9 0.2 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CEP18773.1 - 4.5e-15 55.9 9.3 1.1e-14 54.6 9.3 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RecR PF02132.15 CEP18773.1 - 1 9.0 5.5 1.1 8.9 2.9 2.3 2 0 0 2 2 2 0 RecR protein zf-CCHC PF00098.23 CEP18774.1 - 9.2e-51 167.8 55.5 1.1e-08 34.8 3.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CEP18774.1 - 6.5e-12 45.0 35.6 0.12 12.2 0.5 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CEP18774.1 - 5.7e-05 23.0 41.8 0.082 12.9 0.5 6.4 1 1 6 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 CEP18774.1 - 0.00038 20.1 37.3 0.2 11.4 0.2 6.9 5 2 2 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CEP18774.1 - 0.56 10.1 38.5 0.44 10.4 1.8 6.4 6 1 1 7 7 7 0 Zinc knuckle Anti-TRAP PF15777.5 CEP18774.1 - 0.76 9.8 33.2 0.2 11.6 3.9 4.9 1 1 4 5 5 5 0 Tryptophan RNA-binding attenuator protein inhibitory protein UPF0020 PF01170.18 CEP18775.1 - 3.4e-16 59.5 0.0 3.5e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 CEP18775.1 - 1.4e-09 38.5 0.0 3.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CEP18775.1 - 1.9e-07 30.7 0.1 0.00013 21.5 0.0 2.8 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_11 PF08241.12 CEP18775.1 - 1.9e-07 31.6 0.0 4.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP18775.1 - 2.6e-07 30.2 0.0 4.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CEP18775.1 - 1.7e-06 27.9 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP18775.1 - 0.00021 21.2 0.1 0.086 12.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CEP18775.1 - 0.00093 18.8 0.0 0.0031 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CEP18775.1 - 0.0022 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CEP18775.1 - 0.017 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 CEP18775.1 - 0.038 13.6 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 N6_Mtase PF02384.16 CEP18775.1 - 0.049 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CEP18775.1 - 0.17 11.5 2.2 9.8 5.8 0.0 2.9 2 1 0 2 2 2 0 DNA methylase Vps26 PF03643.15 CEP18776.1 - 3.1e-100 334.7 5.4 3.6e-100 334.5 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 PIG-H PF10181.9 CEP18776.1 - 0.093 12.6 0.6 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component DUF433 PF04255.14 CEP18776.1 - 0.099 12.5 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Pkinase PF00069.25 CEP18777.1 - 2.9e-56 190.7 0.0 3.8e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18777.1 - 3.7e-33 114.9 0.0 5.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP18777.1 - 8.9e-05 21.9 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEP18777.1 - 0.00047 19.8 0.0 0.51 9.9 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CEP18777.1 - 0.0031 16.4 0.1 0.0048 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Trs65 PF12735.7 CEP18778.1 - 1.3e-44 152.9 6.2 2.9e-33 115.6 0.0 3.2 1 1 2 3 3 3 2 TRAPP trafficking subunit Trs65 DUF382 PF04037.13 CEP18779.1 - 9.7e-56 187.4 0.7 9.7e-56 187.4 0.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CEP18779.1 - 1.4e-20 72.9 4.6 3.3e-20 71.7 4.6 1.7 1 0 0 1 1 1 1 PSP Mito_carr PF00153.27 CEP18780.1 - 5.2e-34 116.0 0.3 1.4e-24 85.9 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein TMEM208_SND2 PF05620.11 CEP18780.1 - 0.053 13.3 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Peptidase_M20 PF01546.28 CEP18781.1 - 2.8e-27 95.8 0.0 4.2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CEP18781.1 - 1.4e-21 76.3 15.5 0.00062 20.5 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat M20_dimer PF07687.14 CEP18781.1 - 3.4e-10 39.8 0.0 8.6e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain WD40_like PF17005.5 CEP18781.1 - 4.4e-06 26.2 0.8 0.07 12.4 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 CEP18781.1 - 7.1e-05 23.0 0.1 0.45 10.8 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_2 PF00152.20 CEP18782.1 - 8.4e-75 251.7 0.0 1.1e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CEP18782.1 - 6.6e-08 32.3 0.0 0.00068 19.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CEP18782.1 - 2.7e-07 30.5 0.0 5.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Slp PF03843.13 CEP18782.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family FGase PF05013.12 CEP18783.1 - 1.3e-10 41.9 0.0 0.00035 20.9 0.0 2.4 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase DDE_3 PF13358.6 CEP18784.1 - 0.0009 19.0 0.0 0.0045 16.7 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease DsrD PF08679.11 CEP18784.1 - 0.064 13.5 0.4 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF4642 PF15484.6 CEP18786.1 - 0.14 12.4 3.6 0.15 12.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Dicty_REP PF05086.12 CEP18786.1 - 0.21 9.5 4.8 0.24 9.3 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RP-C_C PF11800.8 CEP18786.1 - 0.28 11.2 4.1 0.31 11.1 4.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region F-protein PF00469.20 CEP18786.1 - 0.62 9.6 3.1 0.74 9.4 3.1 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef RVT_1 PF00078.27 CEP18787.1 - 3.3e-22 79.1 0.0 8.6e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP18787.1 - 7.5e-08 33.0 0.8 2e-07 31.6 0.8 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ADH_zinc_N PF00107.26 CEP18789.1 - 1.9e-19 69.9 0.0 4.1e-19 68.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP18789.1 - 4.7e-19 68.3 4.4 7.3e-19 67.7 4.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CEP18789.1 - 2.1e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CEP18789.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CEP18789.1 - 0.0052 17.8 0.0 0.0093 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 CEP18789.1 - 0.027 13.9 0.2 0.056 12.8 0.2 1.5 1 0 0 1 1 1 0 ThiF family Glyco_hydro_15 PF00723.21 CEP18790.1 - 1.3e-128 429.6 0.0 1.8e-128 429.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 CEP18790.1 - 7.8e-24 84.0 0.0 2.6e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 Interleukin-like EMT inducer SHNi-TPR PF10516.9 CEP18790.1 - 0.071 12.6 0.1 0.21 11.1 0.1 1.8 1 0 0 1 1 1 0 SHNi-TPR Methyltr_RsmB-F PF01189.17 CEP18791.1 - 2.7e-30 105.5 0.0 4.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F SLX9 PF15341.6 CEP18791.1 - 8.7e-05 22.9 0.2 0.00021 21.7 0.2 1.8 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 FtsJ PF01728.19 CEP18791.1 - 0.0085 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF5039 PF16442.5 CEP18791.1 - 0.56 9.7 4.5 1.4 8.5 4.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5039) GATA PF00320.27 CEP18792.1 - 1.2e-30 104.8 19.7 1.2e-15 56.8 5.5 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CEP18792.1 - 1.1e-07 31.3 6.9 0.00025 20.5 0.5 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CEP18792.1 - 0.00042 20.4 7.9 0.095 12.9 0.5 2.8 2 1 1 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 CEP18792.1 - 0.05 13.7 11.6 0.71 10.0 0.1 3.6 4 0 0 4 4 3 0 Zinc ribbon domain zf-RRN7 PF11781.8 CEP18792.1 - 0.19 11.5 9.9 0.19 11.4 0.5 3.0 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CDC45 PF02724.14 CEP18792.1 - 0.23 9.7 3.2 0.41 8.9 3.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DZR PF12773.7 CEP18792.1 - 0.61 10.2 16.8 1.5 8.9 1.1 3.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 CEP18792.1 - 0.72 9.6 10.9 0.42 10.4 1.7 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 CEP18792.1 - 1.3 8.5 13.6 2.1 7.8 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CEP18792.1 - 1.5 8.8 12.7 0.42 10.6 1.0 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 CEP18792.1 - 2.4 8.0 10.2 5.3 6.9 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 CEP18792.1 - 4.1 7.3 13.1 3.1 7.7 0.6 3.5 3 0 0 3 3 3 0 Domain found in IF2B/IF5 IMUP PF15761.5 CEP18792.1 - 4.5 8.0 14.0 0.2 12.3 2.9 3.0 3 0 0 3 3 2 0 Immortalisation up-regulated protein Prim_Zn_Ribbon PF08273.12 CEP18792.1 - 9 6.7 13.3 13 6.2 3.3 3.5 2 2 1 3 3 3 0 Zinc-binding domain of primase-helicase Arm PF00514.23 CEP18793.1 - 1.4e-85 279.0 16.9 2e-13 49.9 0.0 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CEP18793.1 - 1.4e-23 83.2 8.1 5.1e-23 81.3 7.2 2.4 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 CEP18793.1 - 1.1e-19 69.7 9.4 1.9e-19 69.0 1.5 3.0 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_EZ PF13513.6 CEP18793.1 - 1.9e-17 63.4 1.7 4e-06 27.2 0.0 6.3 3 2 4 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 CEP18793.1 - 4.1e-15 55.9 0.0 2.1e-06 28.0 0.0 5.4 2 1 3 6 6 6 5 HEAT repeats HEAT PF02985.22 CEP18793.1 - 2.3e-13 49.1 1.2 0.012 15.8 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 CEP18793.1 - 3.8e-05 22.4 0.0 0.001 17.7 0.0 2.4 1 1 2 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.13 CEP18793.1 - 0.00014 21.4 0.1 0.029 13.8 0.0 3.3 1 1 2 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 CEP18793.1 - 0.0058 16.7 0.3 2.9 8.0 0.0 4.1 2 1 4 6 6 6 2 V-ATPase subunit H RICTOR_V PF14668.6 CEP18793.1 - 0.017 15.3 1.1 2.7 8.3 0.0 3.9 2 2 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 CEP18793.1 - 0.019 15.6 0.2 10 7.1 0.0 4.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Fe_dep_repr_C PF02742.15 CEP18793.1 - 0.14 12.3 1.0 15 5.7 0.1 3.7 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain ATP-synt_C PF00137.21 CEP18794.1 - 1.6e-26 92.4 27.7 9.2e-15 54.7 9.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 CEP18794.1 - 0.0016 18.0 0.2 0.0016 18.0 0.2 2.7 3 1 0 3 3 3 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L G0-G1_switch_2 PF15103.6 CEP18794.1 - 1.2 9.6 2.7 1.4 9.4 0.5 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 Memo PF01875.17 CEP18795.1 - 3.7e-83 278.8 0.2 4.2e-83 278.6 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.32 CEP18796.1 - 2.8e-36 122.9 8.7 1.4e-06 28.9 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18796.1 - 2.3e-10 40.6 1.5 0.029 14.7 0.2 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CEP18796.1 - 4.3e-08 32.5 0.9 1.6 7.6 0.0 5.8 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CEP18796.1 - 8e-07 28.1 6.0 0.16 10.6 0.1 5.0 3 1 2 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CEP18796.1 - 3.8e-05 23.7 0.2 0.018 14.9 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CEP18796.1 - 0.00025 19.9 0.1 0.85 8.3 0.0 4.1 1 1 3 4 4 4 1 Nup133 N terminal like MMS1_N PF10433.9 CEP18796.1 - 0.0004 19.2 0.0 0.0017 17.0 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PALB2_WD40 PF16756.5 CEP18796.1 - 0.0057 15.6 2.0 0.019 13.9 0.1 2.6 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DAZAP2 PF11029.8 CEP18796.1 - 0.022 15.7 5.7 0.05 14.5 5.7 1.5 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Hira PF07569.11 CEP18796.1 - 0.072 12.8 8.5 0.23 11.2 0.0 3.9 3 2 1 4 4 4 0 TUP1-like enhancer of split RRM_1 PF00076.22 CEP18797.1 - 2.5e-07 30.4 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc1_Nup PF09531.10 CEP18797.1 - 0.63 8.7 4.1 0.64 8.6 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CEP18797.1 - 1.1 8.0 2.4 1.3 7.8 2.4 1.1 1 0 0 1 1 1 0 Presenilin Pneumo_att_G PF05539.11 CEP18797.1 - 2 8.0 10.0 3.1 7.3 10.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CNH PF00780.22 CEP18798.1 - 3.1e-41 141.8 0.0 4.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP18798.1 - 5.7e-39 134.2 1.0 1.4e-38 133.0 1.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 CEP18798.1 - 4.4e-11 42.7 0.1 1e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 CEP18798.1 - 4.8e-10 39.7 0.2 1.7e-09 37.9 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.32 CEP18800.1 - 4.1e-32 109.7 14.0 0.00016 22.4 0.0 11.3 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18800.1 - 2.6e-11 43.7 0.0 0.051 13.9 0.0 6.6 4 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP18800.1 - 8.5e-05 22.5 0.0 0.0011 18.9 0.0 2.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEP18800.1 - 0.0059 15.3 0.1 0.26 9.9 0.0 3.4 3 1 0 4 4 4 1 Nucleoporin Nup120/160 DLIC PF05783.11 CEP18800.1 - 0.047 12.5 3.6 0.1 11.4 3.6 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Goodbye PF17109.5 CEP18800.1 - 0.23 11.9 3.3 0.26 11.8 0.2 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain SDA1 PF05285.12 CEP18800.1 - 1 8.7 18.0 2.1 7.7 18.0 1.5 1 0 0 1 1 1 0 SDA1 ArlS_N PF18719.1 CEP18800.1 - 7.2 6.8 8.1 8.2 6.7 2.3 3.2 3 0 0 3 3 3 0 ArlS sensor domain Phage_int_SAM_1 PF02899.17 CEP18802.1 - 0.032 14.5 0.3 0.079 13.3 0.3 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 CEP18802.1 - 0.095 13.2 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Chromo PF00385.24 CEP18805.1 - 1e-09 38.2 0.6 1.7e-09 37.4 0.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CEP18805.1 - 0.0017 18.2 1.7 0.009 15.9 0.4 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF4218 PF13960.6 CEP18808.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) PH_TFIIH PF08567.11 CEP18809.1 - 6.6e-20 71.2 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 CEP18809.1 - 2.9e-17 62.4 0.3 2.9e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 BSD domain WH1 PF00568.23 CEP18810.1 - 9.5e-26 89.9 0.2 1.4e-25 89.3 0.2 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CEP18810.1 - 7.4e-10 39.0 0.3 1.5e-09 38.1 0.3 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 CEP18810.1 - 0.022 14.6 0.4 0.048 13.5 0.4 1.6 1 0 0 1 1 1 0 WH2 motif DUF1539 PF07560.11 CEP18810.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DDE_3 PF13358.6 CEP18811.1 - 4.7e-17 62.1 0.5 8.5e-17 61.3 0.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CEP18811.1 - 1.3e-16 60.6 0.7 2.9e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 CEP18811.1 - 1.8e-07 31.7 1.4 4e-07 30.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP18811.1 - 3.8e-06 26.8 0.1 6.7e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix TrmB PF01978.19 CEP18811.1 - 0.00024 20.9 0.2 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.6 CEP18811.1 - 0.0012 18.6 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 CEP18811.1 - 0.0014 18.7 1.2 0.062 13.4 0.0 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 CEP18811.1 - 0.0014 18.1 0.1 0.085 12.4 0.0 3.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 CEP18811.1 - 0.0037 17.0 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP18811.1 - 0.016 15.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP18811.1 - 0.025 14.7 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_1 PF11427.8 CEP18811.1 - 0.13 12.1 0.1 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Tc3 transposase HTH_19 PF12844.7 CEP18811.1 - 0.14 12.2 2.1 16 5.6 0.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain Sel1 PF08238.12 CEP18812.1 - 9.7e-51 169.1 14.9 4e-08 33.7 0.7 7.4 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 CEP18812.1 - 0.43 10.8 2.9 1.8 8.8 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CEP18812.1 - 2.5 7.8 11.9 10 5.9 0.0 5.3 5 0 0 5 5 5 0 TPR repeat Hist_deacetyl PF00850.19 CEP18813.1 - 2.8e-84 283.2 0.0 3.5e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NAD_binding_4 PF07993.12 CEP18814.1 - 1.1e-07 31.4 0.1 1.9e-07 30.5 0.0 1.4 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 CEP18814.1 - 0.0081 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsX PF02687.21 CEP18814.1 - 0.14 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family Sacchrp_dh_NADP PF03435.18 CEP18814.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CEP18815.1 - 8.4e-33 113.6 0.0 1.5e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 CEP18815.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 CEP18815.1 - 0.0013 18.9 0.0 0.0056 16.9 0.0 2.2 1 0 0 1 1 1 1 Male sterility protein Zwint PF15556.6 CEP18815.1 - 0.014 14.9 0.4 0.038 13.5 0.4 1.6 1 0 0 1 1 1 0 ZW10 interactor 3Beta_HSD PF01073.19 CEP18815.1 - 0.035 13.1 0.0 0.088 11.8 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Telomere_reg-2 PF10193.9 CEP18816.1 - 1.2e-23 83.6 0.0 4.8e-23 81.7 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein DUF1878 PF08963.10 CEP18817.1 - 0.18 12.3 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) DUF5327 PF17261.2 CEP18817.1 - 0.18 12.5 2.5 3.2 8.6 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5327) Aldedh PF00171.22 CEP18818.1 - 7.5e-114 380.8 0.0 9.2e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3425 PF11905.8 CEP18819.1 - 4.7e-09 36.3 0.4 1.9e-08 34.3 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 CEP18819.1 - 0.0026 17.8 9.6 0.0056 16.7 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP18819.1 - 0.13 12.8 10.6 0.29 11.7 10.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Methyltransf_14 PF08484.11 CEP18819.1 - 0.13 12.0 2.8 0.23 11.3 2.8 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Zn_clus PF00172.18 CEP18821.1 - 2.3e-09 37.2 14.8 4.9e-09 36.2 14.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 CEP18822.1 - 9.5e-46 155.9 0.2 1.1e-45 155.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_9 PF14604.6 CEP18823.1 - 2.7e-33 113.6 4.1 1.3e-12 47.4 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 CEP18823.1 - 2.9e-32 110.3 0.0 5.7e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 CEP18823.1 - 2.5e-30 103.8 1.5 7.3e-12 44.7 0.0 3.6 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CEP18823.1 - 2.7e-20 71.8 0.0 1.4e-06 27.9 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_10 PF17902.1 CEP18823.1 - 0.0036 17.3 0.9 6 7.0 0.0 3.9 4 0 0 4 4 4 1 SH3 domain SAM_1 PF00536.30 CEP18823.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FERM_C PF09380.10 CEP18823.1 - 0.036 14.5 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 FERM C-terminal PH-like domain SAM_4 PF18017.1 CEP18823.1 - 0.04 13.9 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_6 PF15406.6 CEP18823.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.2 2 0 0 2 2 1 0 Pleckstrin homology domain MAJIN PF15077.6 CEP18823.1 - 1.3 8.7 6.6 3.3 7.4 6.6 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein eIF3_subunit PF08597.10 CEP18823.1 - 8.5 6.2 27.1 16 5.3 27.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ras PF00071.22 CEP18824.1 - 3.3e-56 189.4 0.1 3.8e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18824.1 - 1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP18824.1 - 1.8e-08 34.0 0.1 2e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP18824.1 - 2.8e-07 30.3 0.1 7.9e-07 28.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP18824.1 - 2.5e-05 24.3 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP18824.1 - 0.00015 21.7 1.6 0.1 12.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CEP18824.1 - 0.0031 16.7 0.2 1.1 8.4 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit YiaAB PF05360.14 CEP18825.1 - 1.3 9.3 6.8 9.5 6.5 0.5 3.3 2 0 0 2 2 2 0 yiaA/B two helix domain F-box-like PF12937.7 CEP18826.1 - 7.6e-05 22.5 2.4 0.00011 22.1 0.2 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 CEP18826.1 - 0.031 14.1 0.7 0.099 12.5 0.0 2.3 2 0 0 2 2 2 0 F-box domain YqcI_YcgG PF08892.11 CEP18826.1 - 0.1 12.4 0.2 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 YqcI/YcgG family PEMT PF04191.13 CEP18828.1 - 1.2e-54 183.1 10.1 2.6e-31 108.2 0.7 3.5 3 0 0 3 3 3 3 Phospholipid methyltransferase DUF853 PF05872.12 CEP18828.1 - 0.013 14.1 0.7 2.3 6.7 1.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) SKICH PF17751.1 CEP18828.1 - 0.031 14.8 0.0 0.14 12.7 0.0 2.1 1 1 0 1 1 1 0 SKICH domain HECW_N PF16562.5 CEP18828.1 - 0.032 14.0 0.1 0.032 14.0 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Arrestin_C PF02752.22 CEP18829.1 - 9.9e-17 61.7 0.0 1.4e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CEP18829.1 - 1.5e-11 44.6 0.0 4.6e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CEP18829.1 - 8.3e-05 22.4 0.0 0.00019 21.2 0.0 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like DnaJ PF00226.31 CEP18830.1 - 4.9e-19 68.2 1.1 2.7e-18 65.8 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain EF1_GNE PF00736.19 CEP18831.1 - 2e-32 111.2 1.6 3.8e-32 110.3 1.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CEP18831.1 - 6.3e-12 45.7 6.4 6.3e-12 45.7 6.4 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 CEP18831.1 - 0.0084 16.3 0.2 0.028 14.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain E1-E2_ATPase PF00122.20 CEP18832.1 - 7.2e-43 146.2 3.7 2.2e-42 144.6 3.7 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CEP18832.1 - 9.3e-41 139.5 9.2 9.3e-41 139.5 9.2 3.4 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CEP18832.1 - 1.8e-25 90.4 0.0 2.3e-12 47.6 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP18832.1 - 1.6e-18 66.5 0.0 3.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CEP18832.1 - 3.1e-12 46.0 0.0 6.9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP18832.1 - 7.1e-05 22.7 0.4 7.1e-05 22.7 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2280 PF10045.9 CEP18832.1 - 0.12 12.7 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Ost4 PF10215.9 CEP18832.1 - 0.85 9.5 6.2 0.87 9.5 3.7 2.4 2 0 0 2 2 2 0 Oligosaccaryltransferase DUF1082 PF06449.11 CEP18833.1 - 0.0092 15.8 0.5 0.015 15.1 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1082) HLH PF00010.26 CEP18834.1 - 7.1e-13 48.3 2.0 1.7e-12 47.1 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L37 PF08561.10 CEP18834.1 - 0.0058 17.1 4.0 0.01 16.3 4.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 PhoU_div PF01865.16 CEP18834.1 - 0.011 15.1 0.2 0.047 13.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF47 Peptidase_S64 PF08192.11 CEP18834.1 - 0.013 14.0 8.2 0.017 13.7 8.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 FIST_C PF10442.9 CEP18834.1 - 0.033 14.1 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 FIST C domain SprA-related PF12118.8 CEP18834.1 - 0.22 10.6 10.6 0.089 11.9 8.4 1.4 1 1 0 1 1 1 0 SprA-related family U79_P34 PF03064.16 CEP18834.1 - 6.2 6.1 15.4 1.3 8.4 11.9 1.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Syntaxin PF00804.25 CEP18835.1 - 3.2e-18 66.1 11.8 6.8e-18 65.1 11.8 1.6 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CEP18835.1 - 4.2e-13 49.1 0.5 4.2e-13 49.1 0.5 2.5 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 CEP18835.1 - 5.2e-06 26.7 6.8 5.2e-06 26.7 6.8 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 CEP18835.1 - 0.0035 17.9 11.3 0.26 11.9 1.8 2.8 2 1 0 2 2 2 2 Syntaxin 6, N-terminal COG6 PF06419.11 CEP18835.1 - 0.0096 14.2 10.9 0.16 10.1 1.7 2.3 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 Snapin_Pallidin PF14712.6 CEP18835.1 - 0.012 16.0 9.6 0.33 11.4 0.9 2.7 2 0 0 2 2 2 0 Snapin/Pallidin MCPsignal PF00015.21 CEP18835.1 - 0.015 15.1 1.1 0.015 15.1 1.1 3.3 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2207 PF09972.9 CEP18835.1 - 0.021 13.6 1.7 0.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NPV_P10 PF05531.12 CEP18835.1 - 0.021 15.3 11.5 0.3 11.6 0.8 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3040 PF11239.8 CEP18835.1 - 0.025 14.9 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Laminin_II PF06009.12 CEP18835.1 - 0.026 14.5 12.4 1.3 9.0 3.1 3.2 2 1 0 2 2 2 0 Laminin Domain II ACTL7A_N PF16840.5 CEP18835.1 - 0.065 13.3 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus Picorna_P3A PF06363.11 CEP18835.1 - 0.068 13.0 0.7 0.19 11.6 0.2 2.1 2 0 0 2 2 1 0 Picornaviridae P3A protein SKA2 PF16740.5 CEP18835.1 - 0.088 12.6 12.7 0.71 9.7 3.0 3.1 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF4709 PF15821.5 CEP18835.1 - 0.099 12.9 8.0 2.9 8.2 1.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) DUF5345 PF17280.2 CEP18835.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.5 3 1 0 3 3 1 0 Family of unknown function (DUF5345) LMBR1 PF04791.16 CEP18835.1 - 0.2 10.5 7.5 0.38 9.6 7.6 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein BLOC1_2 PF10046.9 CEP18835.1 - 0.25 11.7 8.8 6.9 7.0 1.6 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DotU PF09850.9 CEP18835.1 - 0.33 10.6 3.2 1.9 8.1 1.3 2.8 2 1 0 2 2 2 0 Type VI secretion system protein DotU Spectrin PF00435.21 CEP18835.1 - 0.43 11.1 11.9 0.62 10.6 0.6 3.2 2 2 1 3 3 3 0 Spectrin repeat T2SSF PF00482.23 CEP18835.1 - 0.44 10.5 4.7 1.6 8.7 1.7 2.9 1 1 3 4 4 4 0 Type II secretion system (T2SS), protein F TMPIT PF07851.13 CEP18835.1 - 0.47 9.7 9.3 2.6 7.2 2.7 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 CEP18835.1 - 0.68 10.7 11.2 2.3 9.0 2.7 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) RIFIN PF02009.16 CEP18835.1 - 0.78 9.6 13.7 0.041 13.8 2.1 2.1 1 1 0 2 2 2 0 Rifin Latarcin PF10279.9 CEP18835.1 - 1.4 9.4 4.9 1.3 9.4 0.6 2.6 2 2 0 2 2 2 0 Latarcin precursor MCU PF04678.13 CEP18835.1 - 1.4 9.0 8.8 0.17 12.0 1.3 2.3 1 1 0 2 2 2 0 Mitochondrial calcium uniporter DUF745 PF05335.13 CEP18835.1 - 2.2 7.9 19.7 3 7.5 10.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) UPF0184 PF03670.13 CEP18835.1 - 2.8 8.4 8.2 5.9 7.4 0.2 4.0 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) zf-ZPR1 PF03367.13 CEP18835.1 - 3.3 7.5 9.1 0.6 9.9 0.6 2.8 1 1 3 4 4 4 0 ZPR1 zinc-finger domain DASH_Dam1 PF08653.10 CEP18835.1 - 3.6 7.4 6.3 10 6.0 0.2 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 FlaC_arch PF05377.11 CEP18835.1 - 4.7 7.7 9.1 2.8 8.4 0.3 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Sec20 PF03908.13 CEP18835.1 - 4.9 7.1 9.4 0.97 9.4 0.4 3.1 2 2 1 3 3 3 0 Sec20 Synaptobrevin PF00957.21 CEP18835.1 - 5.1 7.0 15.6 1.1 9.1 6.3 3.4 2 2 1 3 3 3 0 Synaptobrevin ISG65-75 PF11727.8 CEP18835.1 - 5.2 6.2 15.0 0.58 9.3 0.6 2.7 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF1664 PF07889.12 CEP18835.1 - 7 6.7 12.7 18 5.4 3.0 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CEP18835.1 - 7.6 6.7 16.3 5.5 7.2 3.2 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CEP18835.1 - 7.6 6.9 24.9 0.63 10.3 0.8 4.5 3 2 1 4 4 3 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 CEP18835.1 - 7.8 7.0 9.3 5.5 7.5 1.1 3.6 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PALP PF00291.25 CEP18836.1 - 2e-79 267.0 0.1 2.5e-79 266.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CEP18836.1 - 2e-40 136.4 0.0 3.3e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase zf-PARP PF00645.18 CEP18837.1 - 0.016 16.0 0.1 0.044 14.7 0.1 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DASH_Dad2 PF08654.10 CEP18839.1 - 2.8e-07 30.9 0.5 4.8e-07 30.1 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 MazG_C PF18722.1 CEP18839.1 - 0.026 14.1 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 MazG C-terminal domain RRM_1 PF00076.22 CEP18840.1 - 1.3e-52 175.5 0.0 5.5e-18 64.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP18840.1 - 0.00014 21.8 0.0 0.16 12.0 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 CEP18840.1 - 0.048 13.7 0.1 0.39 10.8 0.0 2.5 3 1 0 3 3 3 0 Limkain b1 RRM_occluded PF16842.5 CEP18840.1 - 0.13 12.1 0.0 77 3.2 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RNase_H2_suC PF08615.11 CEP18841.1 - 5.2e-18 65.6 0.2 6.5e-18 65.3 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DPBB_1 PF03330.18 CEP18843.1 - 3e-11 43.4 0.6 1.3e-10 41.4 0.6 2.1 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP18843.1 - 0.0018 18.1 0.2 0.0018 18.1 0.2 1.7 2 0 0 2 2 2 1 Barwin family TSP9 PF11493.8 CEP18843.1 - 8.2 7.2 8.3 3.2 8.5 5.0 2.0 2 1 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Chitin_synth_2 PF03142.15 CEP18844.1 - 1.3e-242 806.1 0.1 1.8e-242 805.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP18844.1 - 6.3e-119 398.1 3.1 9.1e-119 397.6 3.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 CEP18844.1 - 4e-16 58.9 0.0 1.1e-11 44.7 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 CEP18844.1 - 1.4e-14 53.7 0.0 6.8e-14 51.5 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 CEP18844.1 - 3.1e-14 53.4 0.0 1.8e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP18844.1 - 5.5e-12 46.0 2.6 5.5e-12 46.0 2.6 1.9 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP18844.1 - 0.00014 21.8 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP18844.1 - 0.0099 15.4 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Methyltr_RsmF_N PF17125.5 CEP18844.1 - 0.041 14.4 0.3 0.12 12.8 0.3 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF4215 PF13948.6 CEP18844.1 - 0.091 13.2 1.4 0.43 11.0 1.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) CDC45 PF02724.14 CEP18844.1 - 2.5 6.3 12.2 3.9 5.7 12.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PNISR PF15996.5 CEP18844.1 - 4.9 7.4 10.4 0.44 10.8 4.8 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Fungal_trans PF04082.18 CEP18845.1 - 8.5e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CARM1 PF11531.8 CEP18845.1 - 0.11 12.7 0.7 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal Zn_clus PF00172.18 CEP18845.1 - 0.7 10.1 11.5 1.4 9.1 11.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 CEP18846.1 - 1.7e-19 69.5 0.4 5.1e-09 35.9 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein BRE PF06113.12 CEP18849.1 - 4e-07 29.2 0.4 6.5e-07 28.5 0.4 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Peptidase_S28 PF05577.12 CEP18850.1 - 1.9e-61 208.2 8.4 4.9e-61 206.8 8.4 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 adh_short PF00106.25 CEP18851.1 - 1.2e-41 142.3 0.2 1.7e-41 141.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP18851.1 - 1.2e-22 80.6 0.0 1.7e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP18851.1 - 1.4e-07 31.6 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEP18851.1 - 0.00068 18.9 0.1 0.00094 18.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CEP18851.1 - 0.003 17.0 0.1 0.0044 16.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CEP18851.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CEP18851.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 CEP18852.1 - 5.6e-57 193.1 0.0 9e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18852.1 - 2.9e-30 105.4 0.0 6.1e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP18852.1 - 1.7e-07 31.8 4.2 7.2e-07 29.8 4.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 CEP18852.1 - 0.00023 20.9 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CEP18852.1 - 0.0027 17.1 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP18852.1 - 0.085 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 CEP18853.1 - 7.2e-10 38.6 0.2 1.5e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP18853.1 - 0.00022 21.0 0.1 0.00049 19.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain AAA_2 PF07724.14 CEP18854.1 - 4.6e-41 140.8 0.1 1.1e-40 139.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.7 CEP18854.1 - 2.4e-14 53.7 0.1 7.4e-08 32.9 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CEP18854.1 - 2.5e-13 48.9 0.1 1.3e-05 25.2 0.0 3.4 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.6 CEP18854.1 - 4e-13 49.6 0.0 1.1e-05 25.9 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CEP18854.1 - 2.4e-12 46.8 0.1 4.2e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP18854.1 - 1.2e-11 44.5 0.0 0.0003 21.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat AAA_5 PF07728.14 CEP18854.1 - 4.4e-10 39.7 0.0 3.5e-09 36.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 CEP18854.1 - 6.7e-10 38.9 0.0 4.4e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CEP18854.1 - 2.6e-08 34.4 0.0 6.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CEP18854.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CEP18854.1 - 8.8e-06 25.1 0.1 6.7e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.6 CEP18854.1 - 5e-05 23.6 0.2 0.00037 20.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CEP18854.1 - 0.00046 20.7 0.7 0.017 15.7 0.0 3.0 2 1 1 3 3 3 1 AAA domain Torsin PF06309.11 CEP18854.1 - 0.00047 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_3 PF07726.11 CEP18854.1 - 0.00063 19.6 0.0 0.0045 16.8 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CEP18854.1 - 0.00083 19.8 0.1 0.033 14.6 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 CEP18854.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CEP18854.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 CEP18854.1 - 0.0099 16.4 0.0 0.048 14.2 0.0 2.2 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 CEP18854.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CEP18854.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MobB PF03205.14 CEP18854.1 - 0.072 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.13 CEP18854.1 - 0.081 12.1 0.3 2.2 7.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CEP18854.1 - 0.083 12.6 0.0 0.42 10.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 CEP18854.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DAP_epimerase PF01678.19 CEP18854.1 - 0.15 12.3 0.2 25 5.1 0.0 2.8 2 0 0 2 2 2 0 Diaminopimelate epimerase Phage_P2_GpE PF06528.12 CEP18854.1 - 0.16 11.5 0.3 0.35 10.5 0.3 1.5 1 0 0 1 1 1 0 Phage P2 GpE Rad51 PF08423.11 CEP18855.1 - 1.1e-126 421.3 0.1 1.3e-126 421.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CEP18855.1 - 1.6e-12 47.5 0.2 2.5e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CEP18855.1 - 1.9e-08 34.8 1.1 5.4e-08 33.3 1.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CEP18855.1 - 3.3e-08 33.3 0.1 4.8e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CEP18855.1 - 0.00011 21.7 1.8 0.0007 19.0 1.8 2.2 1 1 0 1 1 1 1 KaiC HhH-GPD PF00730.25 CEP18855.1 - 0.003 18.0 0.1 0.009 16.5 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DnaB_C PF03796.15 CEP18855.1 - 0.0088 15.4 0.3 0.15 11.3 0.3 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 CEP18855.1 - 0.024 15.0 0.1 0.13 12.7 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAXNEB PF05625.11 CEP18855.1 - 0.061 12.5 2.8 0.12 11.5 1.0 2.0 1 1 1 2 2 2 0 PAXNEB protein AAA_22 PF13401.6 CEP18855.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 CEP18855.1 - 0.082 12.9 0.6 0.19 11.8 0.6 1.6 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain HTH_23 PF13384.6 CEP18856.1 - 4.8e-06 26.2 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP18856.1 - 7e-06 26.1 0.1 1.8e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP18856.1 - 7.8e-06 25.8 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_psq PF05225.16 CEP18856.1 - 0.00044 19.9 0.2 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_1 PF00126.27 CEP18856.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 CEP18856.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR PF01047.22 CEP18856.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 CEP18856.1 - 0.0055 16.2 0.2 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 CEP18856.1 - 0.0086 15.8 0.2 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_3 PF13358.6 CEP18856.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease MarR_2 PF12802.7 CEP18856.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_8 PF02954.19 CEP18856.1 - 0.014 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_3 PF01381.22 CEP18856.1 - 0.017 15.1 0.0 0.052 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix HTH_5 PF01022.20 CEP18856.1 - 0.022 14.6 0.1 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_17 PF12728.7 CEP18856.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 CEP18856.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MerR_1 PF13411.6 CEP18856.1 - 0.037 14.1 0.6 0.15 12.2 0.6 2.1 1 1 0 1 1 1 0 MerR HTH family regulatory protein UPF0175 PF03683.13 CEP18856.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_Mga PF08280.11 CEP18856.1 - 0.095 12.7 0.4 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_AraC PF00165.23 CEP18856.1 - 0.23 11.6 0.5 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Pkinase PF00069.25 CEP18857.1 - 1.3e-54 185.3 0.0 2.9e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18857.1 - 2.1e-22 79.7 0.0 7e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CEP18857.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CEP18857.1 - 0.039 13.5 0.2 0.1 12.1 0.2 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 CEP18858.1 - 3.1e-65 220.2 0.0 4e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18858.1 - 1.4e-32 113.0 0.0 2.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CEP18858.1 - 3.7e-06 27.2 0.0 8.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 CEP18858.1 - 3.8e-05 23.2 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP18858.1 - 0.0001 21.3 0.7 0.0002 20.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CEP18858.1 - 0.001 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CEP18858.1 - 0.075 12.0 0.7 0.16 10.9 0.7 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DUF3512 PF12024.8 CEP18859.1 - 0.0018 17.8 0.0 0.0059 16.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) DUF1075 PF06388.11 CEP18859.1 - 8.6 6.4 6.8 0.49 10.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1075) SRR1 PF07985.12 CEP18860.1 - 2.1e-17 62.9 0.0 3.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 SRR1 Proteasome PF00227.26 CEP18861.1 - 4.8e-52 176.2 0.1 6.7e-52 175.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CEP18861.1 - 1.2e-13 50.2 0.1 1.2e-13 50.2 0.1 2.0 2 0 0 2 2 2 1 Proteasome beta subunits C terminal RNase_H PF00075.24 CEP18862.1 - 6e-38 130.3 0.1 9.1e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 CEP18862.1 - 2.6e-20 72.5 1.9 2.6e-20 72.5 1.9 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin OGG_N PF07934.12 CEP18863.1 - 1.5e-26 92.9 0.7 6.3e-26 90.8 0.2 2.3 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CEP18863.1 - 1.9e-15 57.2 0.0 3.4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CEP18863.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Septin PF00735.18 CEP18865.1 - 2.1e-120 401.3 0.5 2.1e-120 401.3 0.5 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CEP18865.1 - 1.9e-09 37.6 0.3 4.6e-09 36.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP18865.1 - 7.6e-09 35.7 0.9 2.1e-06 27.7 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CEP18865.1 - 3.8e-06 26.6 0.6 0.00025 20.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CEP18865.1 - 0.00013 21.3 0.0 0.00032 20.1 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 CEP18865.1 - 0.00073 19.2 0.0 0.0023 17.5 0.0 1.9 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18865.1 - 0.0025 18.0 0.0 0.0062 16.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CEP18865.1 - 0.0029 18.0 0.0 0.009 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CEP18865.1 - 0.0049 17.2 1.1 0.013 15.8 0.1 2.2 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CEP18865.1 - 0.0058 17.1 3.7 0.02 15.4 0.1 2.6 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 CEP18865.1 - 0.006 16.6 4.6 0.59 10.2 0.1 3.2 2 2 1 3 3 3 2 Dynamin family AAA_29 PF13555.6 CEP18865.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CEP18865.1 - 0.022 14.8 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CEP18865.1 - 0.078 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CEP18865.1 - 0.092 12.5 0.4 4.9 6.9 0.1 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CEP18865.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CEP18865.1 - 0.12 12.1 1.3 0.19 11.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 CEP18865.1 - 0.21 11.1 4.8 0.44 10.1 4.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4776 PF16003.5 CEP18865.1 - 0.31 10.0 8.4 0.47 9.4 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Strep_SA_rep PF06696.11 CEP18865.1 - 0.67 10.0 4.1 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 CEP18865.1 - 1.2 9.2 5.4 4.5 7.3 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 CEP18865.1 - 2.2 7.3 6.2 3.9 6.5 6.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 CEP18865.1 - 3.9 6.4 9.3 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) IFP_35_N PF07334.13 CEP18865.1 - 5.5 7.1 7.5 2.3 8.4 0.0 3.0 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_12 PF13087.6 CEP18867.1 - 1.3e-33 116.4 0.1 4.5e-20 72.1 0.4 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 CEP18867.1 - 3.9e-28 99.0 1.0 1.3e-17 64.5 0.0 3.6 3 1 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 CEP18867.1 - 1e-11 45.1 0.2 0.00012 21.9 0.0 3.9 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CEP18867.1 - 7.3e-05 23.1 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CEP18867.1 - 0.00019 21.2 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CEP18867.1 - 0.014 15.1 0.0 0.3 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2439 PF10382.9 CEP18867.1 - 0.024 14.9 0.1 0.59 10.5 0.1 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2439) DUF262 PF03235.14 CEP18868.1 - 2.8e-16 60.4 3.1 1.3e-15 58.2 3.1 2.1 1 1 0 1 1 1 1 Protein of unknown function DUF262 DHR10 PF18595.1 CEP18869.1 - 0.037 14.1 3.9 0.082 13.0 3.9 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain ATF7IP_BD PF16788.5 CEP18869.1 - 0.038 14.1 2.8 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain SlyX PF04102.12 CEP18869.1 - 0.047 14.3 0.3 5 7.8 0.1 2.4 2 0 0 2 2 2 0 SlyX Val_tRNA-synt_C PF10458.9 CEP18869.1 - 0.067 13.5 0.6 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF4439 PF14530.6 CEP18869.1 - 0.094 13.4 2.8 0.71 10.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4439) DUF5082 PF16888.5 CEP18869.1 - 0.1 12.9 1.4 10 6.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) GPS2_interact PF15784.5 CEP18869.1 - 0.16 12.5 1.5 0.44 11.0 0.7 2.0 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain ABC_tran_CTD PF16326.5 CEP18869.1 - 0.16 12.2 8.3 0.21 11.8 0.2 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Syntaxin-6_N PF09177.11 CEP18869.1 - 0.17 12.4 2.2 0.4 11.3 0.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 CEP18869.1 - 0.26 9.9 0.9 0.34 9.5 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CC2-LZ PF16516.5 CEP18869.1 - 0.42 11.0 2.7 2.1 8.8 0.7 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 CEP18869.1 - 0.43 10.6 1.5 1.6 8.8 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CEP18869.1 - 0.52 10.1 2.8 0.86 9.4 1.0 2.0 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.11 CEP18869.1 - 0.79 10.3 3.3 1.4 9.5 2.0 2.0 1 1 0 1 1 1 0 MerR, DNA binding Prefoldin PF02996.17 CEP18869.1 - 0.95 9.4 3.8 11 5.9 0.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit DivIVA PF05103.13 CEP18869.1 - 0.97 9.5 8.7 0.48 10.5 0.8 2.3 2 0 0 2 2 2 0 DivIVA protein Mito_carr PF00153.27 CEP18870.1 - 5.5e-31 106.4 2.7 1.5e-16 60.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein OrfB_Zn_ribbon PF07282.11 CEP18871.1 - 1e-08 34.9 3.0 1e-08 34.9 3.0 2.2 3 0 0 3 3 3 1 Putative transposase DNA-binding domain TNF PF00229.18 CEP18871.1 - 0.056 13.4 1.1 0.12 12.4 0.4 1.9 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family YfhO PF09586.10 CEP18871.1 - 0.58 8.3 4.4 0.82 7.8 4.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DDE_3 PF13358.6 CEP18874.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_sulph_symp PF00939.19 CEP18875.1 - 1.6e-68 231.9 27.6 1.8e-46 159.2 4.2 3.0 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CEP18875.1 - 5.8e-13 48.7 17.7 5.8e-13 48.7 17.7 2.7 1 1 1 2 2 2 2 Citrate transporter Kelch_4 PF13418.6 CEP18876.1 - 4.4e-21 74.6 5.8 1.6e-05 24.8 0.1 4.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP18876.1 - 6.7e-12 45.2 8.0 6e-05 23.2 0.0 5.6 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CEP18876.1 - 2.3e-08 34.1 2.1 0.00046 20.4 0.2 4.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP18876.1 - 1.1e-07 31.7 0.8 0.69 10.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CEP18876.1 - 8.4e-06 25.6 1.1 0.00061 19.7 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CEP18876.1 - 8.4e-06 25.3 0.3 0.031 13.9 0.1 4.2 4 0 0 4 4 4 1 Kelch motif DUF5534 PF17686.1 CEP18876.1 - 0.18 12.1 0.2 0.48 10.7 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Sortilin-Vps10 PF15902.5 CEP18877.1 - 0 1334.9 11.4 2.9e-137 458.1 0.3 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CEP18877.1 - 3e-128 424.7 32.7 1.1e-44 152.8 3.7 4.3 4 0 0 4 4 4 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CEP18877.1 - 7.8e-06 25.1 68.5 2.2 8.6 0.2 16.2 15 0 0 15 15 15 7 BNR/Asp-box repeat BNR_6 PF15899.5 CEP18877.1 - 0.00091 19.1 10.8 15 6.0 0.1 7.0 5 0 0 5 5 5 3 BNR-Asp box repeat PSII_BNR PF14870.6 CEP18877.1 - 0.22 10.8 6.7 0.61 9.3 0.1 4.5 5 1 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 DUF1682 PF07946.14 CEP18878.1 - 0.099 11.8 18.4 0.12 11.6 18.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SLC12 PF03522.15 CEP18878.1 - 1.3 8.0 15.4 1.4 7.9 15.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 CEP18878.1 - 1.8 8.3 22.7 2.2 8.0 22.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 CEP18878.1 - 4.6 5.5 8.6 5.4 5.3 8.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_polI_A34 PF08208.11 CEP18878.1 - 4.9 7.2 39.1 7.5 6.6 39.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Serinc PF03348.15 CEP18878.1 - 7.9 5.3 12.0 11 4.8 12.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.19 CEP18878.1 - 8.9 5.1 14.5 9.9 4.9 14.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein UBX PF00789.20 CEP18879.1 - 3.4e-17 62.4 0.0 7e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Asp-B-Hydro_N PF05279.11 CEP18879.1 - 0.12 12.5 12.9 0.17 11.9 12.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3752 PF12572.8 CEP18879.1 - 2.7 8.5 22.5 0.22 12.1 16.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF4407 PF14362.6 CEP18879.1 - 4.9 6.4 10.7 7 5.9 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PX PF00787.24 CEP18880.1 - 0.00032 20.6 3.5 0.0007 19.6 3.5 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 CEP18880.1 - 0.0042 17.0 1.0 0.017 15.0 0.1 2.5 3 0 0 3 3 3 1 PB1 domain NolB PF17398.2 CEP18881.1 - 0.12 12.8 0.2 0.27 11.6 0.2 1.5 1 0 0 1 1 1 0 Nodulation protein NolB Glyoxalase PF00903.25 CEP18882.1 - 1.3e-24 86.8 0.1 1.7e-24 86.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CEP18882.1 - 4.4e-08 33.4 0.0 1.2e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CEP18882.1 - 0.00012 21.9 0.3 0.082 12.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 CEP18882.1 - 0.00023 21.9 0.0 0.00052 20.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CEP18882.1 - 0.0012 18.9 0.0 0.014 15.5 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain RNase_T PF00929.24 CEP18883.1 - 5.2e-05 23.9 0.9 0.00073 20.1 0.1 2.4 2 0 0 2 2 2 1 Exonuclease An_peroxidase PF03098.15 CEP18884.1 - 3.3e-34 118.4 1.0 1.2e-23 83.6 1.2 4.1 1 1 1 2 2 2 2 Animal haem peroxidase zf-RVT PF13966.6 CEP18885.1 - 1.7e-06 28.7 0.8 3.9e-06 27.5 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.25 CEP18886.1 - 3.3e-70 236.5 0.0 5.5e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18886.1 - 4.5e-49 167.1 0.0 8.5e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CEP18886.1 - 1.5e-08 34.8 0.1 7.2e-08 32.7 0.0 2.2 3 0 0 3 3 3 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 CEP18886.1 - 2.1e-06 27.3 0.0 0.00034 20.0 0.0 2.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CEP18886.1 - 8.7e-06 24.8 0.8 1.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase SAM_2 PF07647.17 CEP18886.1 - 0.00027 21.0 0.3 0.00064 19.8 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 CEP18886.1 - 0.02 15.5 0.0 0.055 14.1 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PhoD PF09423.10 CEP18886.1 - 0.032 13.3 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase SAM_1 PF00536.30 CEP18886.1 - 0.086 13.3 0.3 0.19 12.2 0.3 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) APH PF01636.23 CEP18886.1 - 0.44 10.4 4.5 0.41 10.5 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family DivIC PF04977.15 CEP18886.1 - 9.5 6.1 8.4 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator FA_hydroxylase PF04116.13 CEP18887.1 - 1.6e-25 90.0 19.4 1.6e-25 90.0 19.4 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily RNase_HII PF01351.18 CEP18888.1 - 5.8e-59 199.3 0.0 1.1e-58 198.3 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease HII DUF5321 PF17254.2 CEP18889.1 - 9.7e-11 41.4 0.0 9.7e-11 41.4 0.0 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5321) Pyr_redox_2 PF07992.14 CEP18890.1 - 1.1e-47 162.7 0.0 1.5e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP18890.1 - 4.9e-09 36.6 0.0 2.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CEP18890.1 - 0.023 14.0 0.1 22 4.2 0.0 3.2 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_3_Rpc31 PF11705.8 CEP18891.1 - 1.8e-32 113.4 8.5 1.8e-32 113.4 8.5 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 CEP18891.1 - 2.3 8.1 14.5 2.5 8.0 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 CEP18891.1 - 6.1 6.1 17.0 7.2 5.8 17.0 1.1 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 CEP18892.1 - 2e-05 25.2 12.9 0.05 14.5 0.3 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16 PF12932.7 CEP18892.1 - 0.048 14.3 0.2 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region bZIP_2 PF07716.15 CEP18894.1 - 6.2e-11 42.2 9.8 6.2e-11 42.2 9.8 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP18894.1 - 6.3e-08 32.6 11.6 6.3e-08 32.6 11.6 2.0 1 1 1 2 2 2 1 bZIP transcription factor HAP1_N PF04849.13 CEP18894.1 - 0.0024 17.1 10.3 0.0039 16.4 10.3 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF3038 PF11237.8 CEP18894.1 - 0.06 13.4 5.9 0.12 12.4 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Pox_A_type_inc PF04508.12 CEP18894.1 - 0.17 11.8 4.7 0.19 11.6 0.5 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Shugoshin_N PF07558.11 CEP18894.1 - 0.71 9.8 8.6 0.096 12.6 2.4 2.5 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Macoilin PF09726.9 CEP18894.1 - 2 6.8 16.3 2.6 6.5 16.3 1.1 1 0 0 1 1 1 0 Macoilin family DPBB_1 PF03330.18 CEP18895.1 - 7e-14 51.9 0.6 2.4e-13 50.2 0.1 2.2 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEP18895.1 - 8e-05 22.5 2.7 9.7e-05 22.2 1.2 1.9 1 1 0 1 1 1 1 Barwin family AP3D1 PF06375.11 CEP18895.1 - 0.26 11.5 12.7 0.55 10.5 12.7 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Presenilin PF01080.17 CEP18895.1 - 0.55 8.9 6.1 0.66 8.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin PIN_4 PF13638.6 CEP18895.1 - 0.84 9.9 6.6 0.72 10.1 4.8 1.6 1 1 1 2 2 2 0 PIN domain Kei1 PF08552.11 CEP18895.1 - 1.7 8.5 3.4 3.3 7.5 3.4 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Atrophin-1 PF03154.15 CEP18895.1 - 2.2 6.5 8.2 2.5 6.3 8.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family BORG_CEP PF14957.6 CEP18895.1 - 3.8 8.7 9.2 8.4 7.6 9.2 1.7 1 1 0 1 1 1 0 Cdc42 effector TraG-D_C PF12696.7 CEP18895.1 - 9.4 6.2 10.1 24 4.9 10.1 1.7 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG RVT_1 PF00078.27 CEP18897.1 - 4.5e-38 131.0 0.0 7.7e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP18897.1 - 2.4e-05 24.0 0.0 7.5e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP18897.1 - 0.0044 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Vitelline_membr PF10542.9 CEP18897.1 - 0.026 14.4 0.4 0.53 10.2 0.1 3.1 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region zf-CCHC PF00098.23 CEP18898.1 - 0.0022 18.0 14.4 0.018 15.1 0.4 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 CEP18898.1 - 0.028 14.2 0.5 0.028 14.2 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEP18898.1 - 1.4 8.8 13.8 1.3 8.9 1.1 2.9 3 0 0 3 3 3 0 Zinc knuckle HLH PF00010.26 CEP18899.1 - 1.7e-17 63.1 2.1 1.7e-17 63.1 2.1 2.7 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain DUF5355 PF17306.2 CEP18899.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5355) Fib_alpha PF08702.10 CEP18899.1 - 0.12 12.6 3.5 0.26 11.5 3.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NMD3 PF04981.13 CEP18901.1 - 2.6e-86 289.0 1.5 3.8e-86 288.5 1.5 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 CEP18901.1 - 0.02 14.9 9.1 0.24 11.4 6.0 2.9 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L24e PF01246.20 CEP18902.1 - 4.7e-31 106.8 7.5 4.7e-31 106.8 7.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e GRIM-19 PF06212.12 CEP18903.1 - 0.73 9.8 6.9 0.22 11.5 1.6 2.3 2 0 0 2 2 2 0 GRIM-19 protein DUF1664 PF07889.12 CEP18903.1 - 2.1 8.4 11.9 0.73 9.9 3.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 CEP18903.1 - 2.8 8.5 13.0 0.47 11.0 4.9 2.5 2 0 0 2 2 2 0 Spectrin repeat YccV-like PF08755.11 CEP18903.1 - 4.1 8.0 7.3 0.47 11.0 1.7 2.2 1 1 1 2 2 2 0 Hemimethylated DNA-binding protein YccV like MRP-L46 PF11788.8 CEP18904.1 - 1.1e-19 71.4 4.6 2e-19 70.5 4.4 1.6 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 CEP18904.1 - 6.7e-06 26.2 0.3 1.3e-05 25.2 0.1 1.6 2 0 0 2 2 2 1 NUDIX domain Rrp15p PF07890.12 CEP18904.1 - 0.079 13.3 3.3 0.16 12.3 3.3 1.5 1 0 0 1 1 1 0 Rrp15p SAND PF01342.21 CEP18904.1 - 0.12 12.1 0.3 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 SAND domain Tcp11 PF05794.13 CEP18904.1 - 0.74 8.8 5.4 2.7 7.0 5.3 1.8 1 1 0 1 1 1 0 T-complex protein 11 Glyco_hydro_18 PF00704.28 CEP18905.1 - 4.8e-68 230.2 0.6 5.8e-68 229.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-HC5HC2H PF13771.6 CEP18906.1 - 2.2e-16 59.9 10.6 2.2e-16 59.9 10.6 2.3 1 1 1 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 CEP18906.1 - 1.2e-13 50.8 1.4 2.3e-13 49.8 1.4 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 CEP18906.1 - 2.2e-13 50.3 14.9 6.4e-13 48.8 14.5 2.0 1 1 1 2 2 2 1 PHD-zinc-finger like domain JmjC PF02373.22 CEP18906.1 - 1.1e-11 45.1 6.9 1.4e-09 38.4 0.2 3.3 3 1 1 4 4 4 2 JmjC domain, hydroxylase YIF1 PF03878.15 CEP18907.1 - 1.2e-83 280.3 1.5 1.9e-83 279.7 1.5 1.3 1 0 0 1 1 1 1 YIF1 Spt20 PF12090.8 CEP18907.1 - 0.022 14.4 7.8 0.029 14.0 7.8 1.2 1 0 0 1 1 1 0 Spt20 family Yip1 PF04893.17 CEP18907.1 - 0.2 11.3 6.8 0.37 10.5 6.8 1.5 1 1 0 1 1 1 0 Yip1 domain TFIIA PF03153.13 CEP18907.1 - 0.25 11.3 17.1 0.32 11.0 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GDI PF00996.18 CEP18908.1 - 1.5e-50 172.1 1.6 4.3e-39 134.3 0.3 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor UPF0060 PF02694.15 CEP18908.1 - 0.12 12.6 0.1 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Acyl-CoA_dh_M PF02770.19 CEP18910.1 - 3.5e-21 75.2 0.1 6.3e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CEP18910.1 - 1.5e-19 70.7 0.3 4.5e-12 46.4 0.1 2.4 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CEP18910.1 - 3.6e-18 65.5 0.1 6.9e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CEP18910.1 - 5.1e-18 65.8 0.0 1.3e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain WD40 PF00400.32 CEP18911.1 - 5.6e-37 125.1 16.5 1.2e-05 26.0 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 CEP18911.1 - 3.4e-07 30.0 0.5 7.9e-07 28.8 0.5 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CEP18911.1 - 1.2e-06 28.7 0.6 0.3 11.4 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP18911.1 - 7.6e-06 25.7 0.2 1.7e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.6 CEP18911.1 - 0.034 14.7 0.7 21 5.8 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain MS_channel PF00924.18 CEP18911.1 - 0.18 11.3 2.0 0.35 10.4 2.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel PALB2_WD40 PF16756.5 CEP18911.1 - 0.2 10.5 2.1 2.9 6.7 0.1 3.3 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain EIF_2_alpha PF07541.12 CEP18912.1 - 3.7e-37 127.0 0.1 1e-36 125.6 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CEP18912.1 - 5.5e-14 52.3 2.4 1.3e-13 51.1 2.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Bap31 PF05529.12 CEP18913.1 - 1.1e-37 128.9 0.2 1.9e-37 128.1 0.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CEP18913.1 - 2.9e-08 33.6 5.5 2.9e-08 33.6 5.5 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain TENA_THI-4 PF03070.16 CEP18913.1 - 0.031 14.1 3.5 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 TENA/THI-4/PQQC family Sec34 PF04136.15 CEP18913.1 - 0.031 14.1 6.0 0.05 13.5 6.0 1.4 1 0 0 1 1 1 0 Sec34-like family DUF2065 PF09838.9 CEP18913.1 - 0.043 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) FAM76 PF16046.5 CEP18913.1 - 0.17 11.2 4.5 0.25 10.6 4.5 1.2 1 0 0 1 1 1 0 FAM76 protein Jnk-SapK_ap_N PF09744.9 CEP18913.1 - 0.33 11.2 13.5 0.15 12.3 11.3 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-CSL PF05207.13 CEP18914.1 - 1.7e-23 82.1 1.2 1.7e-23 82.1 1.2 1.6 2 0 0 2 2 2 1 CSL zinc finger zf-RING_7 PF02591.15 CEP18914.1 - 0.0055 16.9 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 CEP18914.1 - 0.06 13.3 0.9 0.094 12.7 0.3 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CEP18914.1 - 0.06 13.3 0.5 6.9 6.7 0.1 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain RCC1 PF00415.18 CEP18915.1 - 4.8e-78 257.6 2.5 2.5e-11 44.0 0.0 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CEP18915.1 - 4e-40 134.8 31.8 1.6e-07 31.0 0.1 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 CEP18915.1 - 0.025 15.1 1.1 31 5.0 0.0 4.3 5 0 0 5 5 5 0 SUKH-3 immunity protein Hira PF07569.11 CEP18915.1 - 0.025 14.3 0.7 9.7 5.8 0.2 4.1 5 0 0 5 5 5 0 TUP1-like enhancer of split Kelch_2 PF07646.15 CEP18915.1 - 0.077 13.0 1.2 13 6.0 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Gtr1_RagA PF04670.12 CEP18916.1 - 1.3e-72 244.0 0.6 1.8e-72 243.5 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CEP18916.1 - 1.6e-06 27.7 0.7 2.2e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CEP18916.1 - 4.2e-05 23.2 0.1 0.00015 21.4 0.1 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CEP18916.1 - 6.8e-05 22.9 0.0 0.00073 19.6 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CEP18916.1 - 0.00017 21.1 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CEP18916.1 - 0.00032 20.9 0.0 0.0007 19.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CEP18916.1 - 0.0017 17.9 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain WD40 PF00400.32 CEP18917.1 - 0.00062 20.5 0.6 0.84 10.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Clathrin_propel PF01394.20 CEP18917.1 - 0.0043 17.3 0.1 1.8 9.1 0.0 3.4 3 0 0 3 3 3 1 Clathrin propeller repeat ANAPC4_WD40 PF12894.7 CEP18917.1 - 0.0067 16.7 0.0 14 6.1 0.0 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 CEP18917.1 - 0.049 13.6 0.0 2.4 8.2 0.0 2.6 1 1 0 2 2 2 0 WD domain, G-beta repeat Stig1 PF04885.13 CEP18917.1 - 0.11 13.0 0.3 0.11 13.0 0.3 1.6 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 CPSF_A PF03178.15 CEP18917.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 CPSF A subunit region Ofd1_CTDD PF10637.9 CEP18918.1 - 1.2e-75 254.2 0.0 2.2e-72 243.5 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CEP18918.1 - 6e-29 100.6 0.0 1.5e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CEP18918.1 - 3.5e-13 50.3 0.0 7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_repr_REX1B PF14966.6 CEP18919.1 - 1.5e-23 83.2 4.3 7.7e-23 81.0 1.2 2.1 1 1 1 2 2 2 1 DNA repair REX1-B CdvA PF18822.1 CEP18919.1 - 0.0011 18.8 1.2 0.0011 18.8 1.2 2.2 1 1 1 2 2 2 1 CdvA-like coiled-coil domain DUF2634 PF10934.8 CEP18919.1 - 0.0025 17.9 0.4 0.0025 17.9 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2634) Med4 PF10018.9 CEP18919.1 - 0.016 14.9 2.3 0.016 14.9 2.3 2.2 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 APG6_N PF17675.1 CEP18919.1 - 0.072 13.6 6.0 0.06 13.9 4.4 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region LRAT PF04970.13 CEP18919.1 - 0.099 13.0 2.1 0.12 12.6 1.5 1.5 1 1 1 2 2 2 0 Lecithin retinol acyltransferase COG2 PF06148.11 CEP18919.1 - 0.78 9.8 8.2 0.68 10.0 1.0 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 CEP18919.1 - 1.5 8.9 11.6 9.3 6.3 11.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TetR_C_5 PF08360.11 CEP18919.1 - 1.5 9.0 7.3 2.6 8.2 0.4 2.5 2 1 1 3 3 3 0 QacR-like protein, C-terminal region Intein_splicing PF14890.6 CEP18919.1 - 2 8.4 4.4 2.8 7.9 4.4 1.5 1 1 0 1 1 1 0 Intein splicing domain ZYG-11_interact PF05884.12 CEP18919.1 - 2 7.8 3.0 4.1 6.7 2.9 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 FlaC_arch PF05377.11 CEP18919.1 - 6.9 7.2 11.5 1.4 9.4 2.1 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) zf-Tim10_DDP PF02953.15 CEP18920.1 - 3e-25 87.6 2.6 3.5e-25 87.4 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Erf4 PF10256.9 CEP18920.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family CNH PF00780.22 CEP18921.1 - 1.1e-54 185.9 0.0 1.9e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP18921.1 - 5.1e-32 111.6 1.3 1.2e-31 110.4 1.3 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP18921.1 - 3.6e-19 69.2 0.1 1.3e-18 67.4 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Metallophos PF00149.28 CEP18923.1 - 4.2e-18 66.6 0.1 9.9e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CEP18923.1 - 5e-08 33.3 0.0 7.3e-05 23.0 0.0 3.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FAD_binding_3 PF01494.19 CEP18924.1 - 4.5e-21 75.5 0.1 1.8e-20 73.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 CEP18924.1 - 0.00091 18.4 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 CEP18924.1 - 0.0019 17.9 0.1 0.2 11.2 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CEP18924.1 - 0.0022 17.2 0.1 0.0075 15.4 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CEP18924.1 - 0.0022 18.2 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CEP18924.1 - 0.0041 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 CEP18924.1 - 0.0046 15.9 2.5 0.14 10.9 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 CEP18924.1 - 0.0053 16.0 0.1 0.55 9.4 0.0 2.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP18924.1 - 0.05 14.2 0.1 0.35 11.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEP18924.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HTH_Tnp_Tc3_2 PF01498.18 CEP18926.1 - 1.4e-16 60.5 1.4 6.1e-16 58.4 0.6 2.2 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CEP18926.1 - 7.6e-08 32.9 0.9 1.6e-07 31.8 0.9 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP18926.1 - 9.2e-07 28.8 0.4 3e-05 24.0 0.1 2.5 3 0 0 3 3 3 1 Winged helix-turn helix TrmB PF01978.19 CEP18926.1 - 6.1e-05 22.8 0.1 0.00065 19.5 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 CEP18926.1 - 8e-05 22.3 0.1 0.2 11.5 0.0 3.0 3 0 0 3 3 3 2 Homeodomain-like domain HTH_7 PF02796.15 CEP18926.1 - 0.00016 21.7 1.0 0.028 14.5 0.0 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 CEP18926.1 - 0.00032 20.4 0.2 0.013 15.3 0.0 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 CEP18926.1 - 0.0022 17.5 0.2 0.04 13.5 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 CEP18926.1 - 0.0027 17.5 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_28 PF13518.6 CEP18926.1 - 0.0065 16.6 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 CEP18926.1 - 0.013 15.0 0.9 9 5.9 0.1 3.2 3 1 0 3 3 3 0 Sigma-70, region 4 LacI PF00356.21 CEP18926.1 - 0.014 15.1 0.2 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Mor PF08765.11 CEP18926.1 - 0.021 14.8 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Mor transcription activator family DUF2774 PF11242.8 CEP18926.1 - 0.075 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.12 CEP18926.1 - 0.099 12.3 0.1 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_10 PF04967.12 CEP18926.1 - 0.14 12.0 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain DUF1287 PF06940.11 CEP18927.1 - 0.099 12.3 1.2 0.13 11.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Integrase_H2C2 PF17921.1 CEP18928.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP18928.1 - 0.0037 17.5 0.0 0.0076 16.4 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Cellulase PF00150.18 CEP18929.1 - 2.7e-14 53.3 0.3 4.9e-14 52.4 0.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 CEP18930.1 - 2.1e-48 165.0 0.0 6.8e-48 163.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18930.1 - 2.2e-21 76.3 0.3 7.3e-17 61.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 CEP18930.1 - 1.7e-06 27.9 0.3 0.073 12.7 0.0 3.1 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CEP18930.1 - 0.00024 21.1 0.0 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CEP18930.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CEP18930.1 - 0.065 12.2 0.1 0.065 12.2 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain WGR PF05406.15 CEP18930.1 - 0.1 12.7 1.7 0.27 11.3 1.7 1.7 1 0 0 1 1 1 0 WGR domain SR-25 PF10500.9 CEP18930.1 - 0.54 9.8 7.9 1.2 8.6 7.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CEP18930.1 - 1.2 9.8 6.6 2.7 8.7 6.6 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Syntaphilin PF15290.6 CEP18930.1 - 9.5 5.8 9.5 19 4.7 9.5 1.4 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp tRNA_Me_trans PF03054.16 CEP18931.1 - 1.1e-116 389.5 0.0 1.3e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 CEP18931.1 - 3.6e-05 23.0 0.0 0.00026 20.2 0.0 2.0 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 CEP18931.1 - 6.3e-05 22.6 0.0 0.00033 20.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 CEP18931.1 - 0.0098 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 CEP18931.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 CEP18931.1 - 0.064 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase D-ser_dehydrat PF14031.6 CEP18931.1 - 0.14 12.8 0.1 1.6 9.4 0.0 2.6 3 1 0 3 3 3 0 Putative serine dehydratase domain Sec1 PF00995.23 CEP18932.1 - 2.8e-122 409.9 0.1 3.8e-122 409.4 0.1 1.2 1 0 0 1 1 1 1 Sec1 family 60KD_IMP PF02096.20 CEP18932.1 - 0.024 14.5 0.8 0.045 13.7 0.8 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Cas_Csn2 PF09711.10 CEP18933.1 - 0.02 14.6 1.3 0.089 12.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csn2) SR-25 PF10500.9 CEP18933.1 - 0.13 11.8 2.5 0.25 10.9 2.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nup54 PF13874.6 CEP18934.1 - 9.7e-37 126.2 19.1 4.2e-36 124.1 8.6 2.4 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CEP18934.1 - 0.00094 20.0 97.3 0.0013 19.5 41.8 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region NPV_P10 PF05531.12 CEP18934.1 - 0.67 10.5 11.2 16 6.0 0.4 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Coiled-coil_56 PF09813.9 CEP18935.1 - 0.00025 21.0 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF423 PF04241.15 CEP18935.1 - 0.027 14.7 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF4910 PF16254.5 CEP18937.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Uteroglobin PF01099.17 CEP18937.1 - 0.23 11.8 0.8 0.59 10.5 0.8 1.6 1 0 0 1 1 1 0 Uteroglobin family DDE_3 PF13358.6 CEP18938.1 - 2.4e-22 79.3 0.6 6.5e-12 45.4 0.0 3.5 2 2 2 4 4 4 3 DDE superfamily endonuclease CRIM PF16978.5 CEP18939.1 - 4.4e-42 143.6 0.0 3.8e-41 140.5 0.0 2.4 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CEP18939.1 - 3.8e-28 98.0 0.8 8.1e-28 96.9 0.8 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 CEP18939.1 - 0.13 12.4 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain NUP214 PF16755.5 CEP18940.1 - 5.9e-13 48.8 4.2 8.8e-13 48.2 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 CEP18940.1 - 0.00028 21.1 0.0 1.1 9.6 0.0 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain FPL PF09758.9 CEP18940.1 - 0.031 14.3 0.5 0.06 13.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein Flu_B_M2 PF04772.12 CEP18940.1 - 0.088 13.1 0.5 0.19 12.0 0.5 1.5 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) NopRA1 PF16201.5 CEP18940.1 - 0.09 12.4 0.5 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 WHEP-TRS PF00458.20 CEP18940.1 - 0.17 12.1 1.0 0.38 11.0 1.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain ASF1_hist_chap PF04729.13 CEP18941.1 - 5.2e-71 237.6 0.7 6.2e-71 237.3 0.7 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0172 PF03665.13 CEP18941.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Cys_Met_Meta_PP PF01053.20 CEP18942.1 - 6.7e-158 525.2 0.0 7.5e-158 525.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CEP18942.1 - 9.8e-06 24.8 0.2 9.8e-05 21.5 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CEP18942.1 - 7.6e-05 22.2 0.7 0.00041 19.8 0.7 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CEP18942.1 - 9.1e-05 21.8 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP18942.1 - 0.011 15.0 0.3 0.04 13.2 0.3 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase Alliinase_C PF04864.13 CEP18942.1 - 0.041 12.8 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Allinase AhpC-TSA PF00578.21 CEP18943.1 - 2.3e-34 118.0 0.1 2.8e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CEP18943.1 - 5e-15 55.5 0.0 6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CEP18943.1 - 0.00016 21.8 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Rcd1 PF04078.13 CEP18944.1 - 7e-126 418.8 2.9 7e-126 418.8 2.9 1.5 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 CEP18945.1 - 1.8e-55 188.2 0.2 1.8e-55 188.2 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP18945.1 - 2.4e-41 141.8 0.2 3.9e-41 141.1 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CEP18945.1 - 0.00013 22.1 0.1 0.0003 21.0 0.1 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 CEP18945.1 - 0.018 13.8 0.4 0.036 12.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Raco_middle PF17651.1 CEP18945.1 - 0.022 14.4 0.3 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 RACo middle region Tropomyosin_1 PF12718.7 CEP18945.1 - 0.071 13.3 5.8 0.18 12.0 5.8 1.7 1 0 0 1 1 1 0 Tropomyosin like Ras PF00071.22 CEP18946.1 - 3.3e-57 192.6 0.7 3.9e-57 192.4 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP18946.1 - 8.2e-23 80.9 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP18946.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEP18946.1 - 0.00019 21.4 0.2 0.44 10.4 0.0 2.5 1 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CEP18946.1 - 0.00085 18.9 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP18946.1 - 0.0053 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 CEP18946.1 - 0.0071 15.6 0.2 1.7 7.8 0.1 2.1 1 1 1 2 2 2 2 NB-ARC domain MMR_HSR1_Xtn PF16897.5 CEP18946.1 - 0.029 14.4 0.3 1.3 9.1 0.0 2.4 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA PF00004.29 CEP18946.1 - 0.084 13.3 0.1 2 8.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BING4CT PF08149.11 CEP18947.1 - 3.6e-39 132.4 0.0 2.5e-37 126.5 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CEP18947.1 - 1.2e-10 41.8 0.6 4.9e-05 24.0 0.0 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP18947.1 - 3.1e-08 33.8 0.0 3 8.2 0.1 5.3 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CEP18947.1 - 1.5e-05 24.3 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.6 CEP18947.1 - 0.0089 15.6 0.0 0.051 13.1 0.0 2.0 1 1 1 2 2 2 1 PQQ-like domain MqsA_antitoxin PF15731.5 CEP18948.1 - 0.15 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA CotH PF08757.11 CEP18949.1 - 3.6e-46 158.2 3.4 3.6e-46 158.2 3.4 1.8 2 0 0 2 2 2 1 CotH kinase protein Pam16 PF03656.13 CEP18949.1 - 3.8e-16 59.2 10.0 1.2e-15 57.7 7.8 2.6 2 1 0 2 2 2 1 Pam16 Synaptobrevin PF00957.21 CEP18950.1 - 1.2e-33 114.7 1.1 1.8e-33 114.2 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CEP18950.1 - 4.4e-29 100.4 0.0 7.1e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MCU PF04678.13 CEP18950.1 - 0.079 13.1 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Glyco_hydro_17 PF00332.18 CEP18951.1 - 2.6e-12 47.0 0.5 2.4e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 MRP-S28 PF10213.9 CEP18952.1 - 3.7e-40 137.3 1.5 4.8e-40 136.9 0.5 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF1641 PF07849.11 CEP18953.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) ComZ PF10815.8 CEP18953.1 - 0.097 12.7 1.4 9.8 6.3 1.4 2.3 1 1 1 2 2 2 0 ComZ DUF3484 PF11983.8 CEP18953.1 - 0.23 12.6 5.1 0.68 11.1 5.1 2.1 1 1 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Pneumo_att_G PF05539.11 CEP18954.1 - 0.42 10.2 8.6 0.59 9.7 8.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RPE65 PF03055.15 CEP18955.1 - 1.7e-85 288.0 0.0 2.2e-85 287.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Acetyltransf_1 PF00583.25 CEP18956.1 - 5.7e-14 52.4 0.0 7.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CEP18956.1 - 1.6e-11 44.2 0.0 2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CEP18956.1 - 3.4e-10 40.2 0.0 5.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP18956.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CEP18956.1 - 3e-05 24.7 0.0 3.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CEP18956.1 - 0.0002 21.1 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 CEP18956.1 - 0.0009 19.3 0.1 0.0033 17.5 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP18956.1 - 0.0028 17.7 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CEP18956.1 - 0.012 15.7 0.0 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP18957.1 - 1.1e-10 41.5 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP18957.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP18957.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CEP18957.1 - 3.6e-05 23.5 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 CEP18957.1 - 0.00052 19.9 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP18957.1 - 0.0015 18.6 0.0 0.025 14.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CEP18957.1 - 0.026 14.7 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 CEP18957.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 CEP18957.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase F1F0-ATPsyn_F PF10791.9 CEP18958.1 - 1.1e-32 112.4 0.1 1.4e-32 112.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 CEP18958.1 - 0.0088 16.4 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f RTC4 PF14474.6 CEP18959.1 - 2.7e-27 95.3 0.0 4.8e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain SR-25 PF10500.9 CEP18959.1 - 8.5 5.9 9.1 2.4 7.7 4.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NGP1NT PF08153.12 CEP18961.1 - 8.8e-55 184.4 0.3 2.8e-54 182.8 0.3 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CEP18961.1 - 5.5e-17 61.9 0.1 1.1e-12 48.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 CEP18961.1 - 3.5e-05 23.3 0.1 0.053 13.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 CEP18961.1 - 0.00011 21.8 0.0 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CEP18961.1 - 0.0019 18.2 0.0 0.006 16.5 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CEP18961.1 - 0.0049 16.4 0.0 0.54 9.8 0.0 3.5 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Glyco_transf_5 PF08323.11 CEP18961.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Dynamin_N PF00350.23 CEP18961.1 - 1.4 9.0 13.6 2.5 8.1 0.0 4.4 4 1 1 5 5 5 0 Dynamin family L51_S25_CI-B8 PF05047.16 CEP18962.1 - 1.2e-11 44.3 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Vac7 PF12751.7 CEP18963.1 - 6.3e-15 55.5 13.1 6.3e-15 55.5 13.1 3.2 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 adh_short_C2 PF13561.6 CEP18963.1 - 2.8e-09 36.9 0.1 6.1e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP18963.1 - 3.1e-06 26.8 0.1 6.5e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Glycos_transf_2 PF00535.26 CEP18964.1 - 9.7e-06 25.5 0.0 2.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEP18964.1 - 0.00027 20.9 0.2 0.0065 16.4 0.1 2.7 2 1 1 3 3 3 1 Glycosyltransferase like family 2 DC_STAMP PF07782.13 CEP18964.1 - 0.077 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 DC-STAMP-like protein Bromodomain PF00439.25 CEP18965.1 - 1.8e-126 412.5 9.8 3.6e-21 75.0 0.0 6.9 6 0 0 6 6 6 6 Bromodomain Peptidase_M1 PF01433.20 CEP18965.1 - 1.5e-05 24.7 1.1 0.00023 20.8 0.0 2.7 3 0 0 3 3 3 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CEP18965.1 - 0.00016 21.9 0.8 0.26 11.5 0.2 2.9 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain zf-CHCC PF10276.9 CEP18966.1 - 4.3e-17 61.9 2.7 6e-17 61.4 2.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 CEP18966.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Zinc Finger domain TPR_1 PF00515.28 CEP18967.1 - 1.1e-08 34.5 7.2 0.01 15.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP18967.1 - 1.1e-05 25.1 8.0 0.13 12.4 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 CEP18967.1 - 0.0006 19.9 0.3 0.002 18.2 0.3 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 CEP18967.1 - 0.0022 18.2 0.7 3.6 7.9 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 CEP18967.1 - 0.014 15.3 0.2 0.014 15.3 0.2 2.9 3 0 0 3 3 3 0 UBA/TS-N domain TPR_8 PF13181.6 CEP18967.1 - 0.24 11.7 7.5 23 5.5 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 CEP18968.1 - 1.3e-51 174.4 0.4 2.2e-51 173.6 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Tnp_22_trimer PF17489.2 CEP18968.1 - 0.2 11.6 2.7 0.28 11.2 0.2 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain Mito_carr PF00153.27 CEP18969.1 - 4.9e-51 170.6 5.0 8e-19 67.4 2.4 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP18969.1 - 0.00013 21.2 0.1 0.089 11.9 0.0 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease DUF2268 PF10026.9 CEP18969.1 - 0.057 13.0 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Abhydrolase_3 PF07859.13 CEP18970.1 - 7.8e-23 81.4 0.0 1.2e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP18970.1 - 1.3e-09 37.4 0.0 4.3e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CEP18970.1 - 0.029 13.9 0.0 0.084 12.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family STIMATE PF12400.8 CEP18971.1 - 3.4e-40 137.5 10.6 5e-40 136.9 10.6 1.2 1 0 0 1 1 1 1 STIMATE family Zip PF02535.22 CEP18971.1 - 0.19 10.9 0.7 0.26 10.5 0.7 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter DEAD PF00270.29 CEP18972.1 - 6.9e-41 139.9 0.0 1.5e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP18972.1 - 5.4e-22 78.2 0.6 1.7e-21 76.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ATP_bind_3 PF01171.20 CEP18972.1 - 5e-17 62.3 0.0 9.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CEP18972.1 - 1e-16 60.1 4.8 1e-16 60.1 4.8 2.9 3 0 0 3 3 3 1 Zinc-ribbon ResIII PF04851.15 CEP18972.1 - 7.4e-09 35.8 0.0 7.4e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CEP18972.1 - 0.011 16.0 0.3 1 9.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 CEP18972.1 - 1.9 7.6 3.4 2.9 7.0 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 CEP18972.1 - 5.7 5.6 11.6 13 4.4 11.6 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Beta-lactamase PF00144.24 CEP18976.1 - 2.9e-06 26.8 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CEP18976.1 - 0.0066 16.1 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family GDPD PF03009.17 CEP18976.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Beta-lactamase2 PF13354.6 CEP18977.1 - 1.7e-26 93.1 0.0 2.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 CEP18977.1 - 9.5e-18 64.5 0.0 2.2e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 CEP18977.1 - 3.4e-06 26.7 0.0 4.8e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Gpr1_Fun34_YaaH PF01184.19 CEP18980.1 - 3.7e-28 98.6 19.1 5e-28 98.1 19.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF485 PF04341.12 CEP18980.1 - 0.66 10.0 8.8 1.1 9.2 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 ABC2_membrane PF01061.24 CEP18981.1 - 1.6e-85 285.8 68.9 6.8e-48 162.9 17.4 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEP18981.1 - 1.7e-37 129.0 0.0 4.5e-21 75.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEP18981.1 - 1.8e-32 111.1 8.0 1.1e-25 89.3 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP18981.1 - 1.4e-14 54.4 0.2 3.9e-14 53.0 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CEP18981.1 - 1.2e-13 50.9 40.5 1.5e-07 30.9 19.4 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CEP18981.1 - 1.4e-05 25.1 0.6 0.00032 20.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEP18981.1 - 1.6e-05 25.4 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CEP18981.1 - 2.2e-05 24.1 0.5 0.017 14.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CEP18981.1 - 3.7e-05 23.7 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CEP18981.1 - 0.00071 20.1 0.1 0.28 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CEP18981.1 - 0.00096 19.3 0.2 0.6 10.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP18981.1 - 0.0013 19.0 0.1 0.71 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CEP18981.1 - 0.0069 16.1 0.3 2.1 8.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CEP18981.1 - 0.007 16.0 0.0 0.035 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.7 CEP18981.1 - 0.038 13.3 13.1 0.16 11.2 6.0 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Zeta_toxin PF06414.12 CEP18981.1 - 0.041 13.1 0.0 0.67 9.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 CEP18981.1 - 0.058 13.5 1.9 11 6.1 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase Rad17 PF03215.15 CEP18981.1 - 0.075 12.9 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 CEP18981.1 - 0.086 12.4 0.9 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CEP18981.1 - 0.11 12.8 1.0 0.98 9.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CEP18981.1 - 0.12 12.3 0.3 5.4 6.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 CEP18981.1 - 0.64 10.5 0.0 0.64 10.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain E1_DerP2_DerF2 PF02221.15 CEP18984.1 - 1.7e-16 60.8 0.0 2e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 ML domain zf-H2C2_2 PF13465.6 CEP18985.1 - 3e-23 81.2 24.3 8.2e-08 32.3 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CEP18985.1 - 1.7e-18 65.9 31.1 2.9e-05 24.3 3.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP18985.1 - 1.4e-09 37.9 28.6 0.004 17.9 2.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CEP18985.1 - 0.00016 21.3 9.2 0.066 13.0 0.2 4.6 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CEP18985.1 - 0.00016 21.8 1.3 1.3 9.4 0.1 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CEP18985.1 - 0.00049 20.4 4.0 9.1 6.8 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Ogr_Delta PF04606.12 CEP18985.1 - 0.13 12.2 4.9 2.2 8.3 0.2 2.8 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger NAM-associated PF14303.6 CEP18985.1 - 0.27 11.9 4.1 0.46 11.2 4.1 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-TRAF PF02176.18 CEP18985.1 - 0.33 11.7 10.6 4.8 7.9 2.4 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger FOXP-CC PF16159.5 CEP18985.1 - 1 10.0 8.2 1.9 9.2 0.2 3.7 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-LYAR PF08790.11 CEP18985.1 - 2.4 8.1 7.8 11 6.0 0.6 4.1 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 CEP18985.1 - 3.5 7.7 17.8 7.6 6.7 2.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CEP18985.1 - 6.1 6.7 21.9 1.6 8.6 2.2 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF3924 PF13062.6 CEP18986.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) FCP1_C PF09309.10 CEP18986.1 - 0.51 10.2 2.5 0.39 10.5 0.3 1.8 2 0 0 2 2 2 0 FCP1, C-terminal Mononeg_mRNAcap PF14318.6 CEP18986.1 - 3.6 6.8 10.0 0.79 8.9 0.2 2.8 2 1 1 3 3 3 0 Mononegavirales mRNA-capping region V PET117 PF15786.5 CEP18987.1 - 1.5e-23 82.8 2.8 1.7e-23 82.7 2.8 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial SieB PF14163.6 CEP18987.1 - 0.0087 15.6 0.2 0.0098 15.4 0.2 1.1 1 0 0 1 1 1 1 Super-infection exclusion protein B Comm PF15957.5 CEP18987.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Commissureless Ribosomal_S27 PF01599.19 CEP18988.1 - 3e-27 94.5 2.5 5.3e-27 93.7 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CEP18988.1 - 5.8e-14 51.6 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CEP18988.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CEP18988.1 - 0.012 15.8 0.3 0.02 15.1 0.3 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain CRC_subunit PF08624.10 CEP18989.1 - 1.3e-25 90.4 3.6 5.7e-22 78.6 0.6 2.7 2 1 1 3 3 3 2 Chromatin remodelling complex Rsc7/Swp82 subunit UQ_con PF00179.26 CEP18990.1 - 1.6e-50 170.4 0.0 1.8e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hydrolase_3 PF08282.12 CEP18991.1 - 6.8e-56 189.8 0.0 7.8e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CEP18991.1 - 3.7e-13 49.6 0.0 3.2e-06 26.9 0.0 2.6 2 1 1 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CEP18991.1 - 1.4e-09 38.5 0.1 0.013 15.8 0.0 3.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CEP18991.1 - 0.00067 20.1 0.1 8.8 6.7 0.0 3.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 CEP18991.1 - 0.00094 18.4 0.0 1 8.5 0.0 2.3 2 1 0 2 2 2 2 Trehalose-phosphatase Hydrolase_6 PF13344.6 CEP18991.1 - 0.0066 16.5 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP18991.1 - 0.012 15.7 0.0 3.7 7.6 0.0 3.0 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 CEP18992.1 - 1.1e-58 198.7 2.8 5.4e-56 189.9 0.0 3.4 2 1 1 3 3 3 2 Protein kinase domain Ribosomal_L4 PF00573.22 CEP18992.1 - 4.2e-40 137.5 0.9 4.2e-40 137.5 0.9 2.3 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CEP18992.1 - 3.5e-30 103.9 1.0 3.5e-30 103.9 1.0 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pkinase_Tyr PF07714.17 CEP18992.1 - 1.8e-29 102.8 0.0 9.5e-28 97.2 0.0 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 CEP18992.1 - 5.2e-11 42.2 0.1 1.2e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CEP18992.1 - 7.7e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP18992.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CEP18992.1 - 0.032 13.8 0.1 0.089 12.4 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CEP18992.1 - 0.033 13.5 0.1 0.078 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_72 PF03198.14 CEP18993.1 - 1.7e-133 444.7 1.6 2.2e-133 444.4 1.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CEP18993.1 - 3.6e-12 46.8 0.7 1.2e-11 45.1 0.7 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 CEP18993.1 - 0.00099 18.6 0.3 0.014 14.8 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 CEP18993.1 - 0.0076 15.8 0.1 0.061 12.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core ATP-synt_ab PF00006.25 CEP18994.1 - 9.9e-64 214.9 0.0 2.1e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CEP18994.1 - 1.7e-23 82.9 2.5 3.2e-23 82.0 1.7 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 CEP18994.1 - 0.0088 15.2 0.7 0.016 14.4 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 CEP18994.1 - 0.01 15.8 0.1 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CEP18994.1 - 0.014 15.8 0.1 0.057 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CEP18994.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CEP18994.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 CEP18994.1 - 0.034 13.5 0.1 0.07 12.5 0.1 1.5 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 CEP18994.1 - 0.034 14.0 0.8 0.22 11.4 0.8 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA PF00004.29 CEP18994.1 - 0.048 14.1 0.1 0.58 10.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CEP18994.1 - 0.061 13.7 0.8 0.29 11.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CEP18994.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SNARE_assoc PF09335.11 CEP18995.1 - 1.2e-10 41.9 4.7 1.2e-10 41.9 4.7 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Med14 PF08638.11 CEP18996.1 - 6.6e-53 179.0 1.7 5.1e-33 114.1 0.3 2.8 2 1 1 3 3 3 2 Mediator complex subunit MED14 DHHC PF01529.20 CEP18996.1 - 4.2e-36 124.0 10.0 1.1e-35 122.6 10.0 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.7 CEP18996.1 - 0.42 10.7 4.8 0.93 9.6 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CEP18996.1 - 0.86 9.1 4.6 2.1 7.9 4.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Tim17 PF02466.19 CEP18997.1 - 1.1e-25 90.2 8.5 1.7e-25 89.5 8.5 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family C2 PF00168.30 CEP18998.1 - 9.1e-81 266.8 3.2 3.4e-19 69.0 0.0 5.4 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 CEP18998.1 - 2.6e-06 27.0 0.0 6.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Thioredoxin PF00085.20 CEP18999.1 - 4.6e-09 36.2 0.0 4.3e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Oxidored_FMN PF00724.20 CEP19000.1 - 5.3e-102 341.6 0.0 6e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 CEP19000.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme TPP_enzyme_N PF02776.18 CEP19001.1 - 4.9e-31 107.6 0.0 8.8e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CEP19001.1 - 3.4e-20 72.2 0.0 1.1e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CEP19001.1 - 4.8e-18 65.4 0.0 2.3e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1_like PF12832.7 CEP19001.1 - 0.094 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 MFS_1 like family DUF362 PF04015.12 CEP19001.1 - 0.11 12.8 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Proteasome PF00227.26 CEP19002.1 - 2.3e-52 177.3 0.0 2.9e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP19002.1 - 1.9e-12 46.6 0.0 4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pox_A14 PF05767.12 CEP19003.1 - 0.0076 16.4 0.0 0.0091 16.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 NB PF04159.13 CEP19003.1 - 0.017 15.2 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 NB glycoprotein TMEM154 PF15102.6 CEP19003.1 - 0.021 14.7 0.2 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF2970 PF11174.8 CEP19003.1 - 0.025 14.4 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) EssA PF10661.9 CEP19003.1 - 0.056 13.3 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Gypsy PF07253.11 CEP19003.1 - 0.058 11.9 0.0 0.064 11.8 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein Orf78 PF06024.12 CEP19003.1 - 0.088 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 CEP19003.1 - 0.099 13.5 0.1 0.24 12.3 0.0 1.7 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Asp4 PF16996.5 CEP19003.1 - 0.56 10.0 4.1 0.47 10.3 2.2 1.8 1 1 1 2 2 2 0 Accessory secretory protein Sec Asp4 PfkB PF00294.24 CEP19004.1 - 2.6e-41 141.9 0.3 3.8e-41 141.3 0.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CEP19004.1 - 0.0042 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF5305 PF17231.2 CEP19004.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) CcmD PF04995.14 CEP19004.1 - 0.098 12.8 0.3 0.19 11.8 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Ceramidase PF05875.12 CEP19004.1 - 0.12 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Ceramidase DUF4271 PF14093.6 CEP19004.1 - 0.82 9.5 5.6 6.6 6.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) FeoB_associated PF12669.7 CEP19004.1 - 1.4 9.4 4.1 3.7 8.0 4.1 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein NPCBM_assoc PF10633.9 CEP19005.1 - 0.001 19.3 0.0 2.4 8.5 0.0 2.6 2 1 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase E1_DerP2_DerF2 PF02221.15 CEP19005.1 - 0.092 13.2 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 ML domain ADH_zinc_N PF00107.26 CEP19006.1 - 6.9e-24 84.3 0.0 1.3e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP19006.1 - 5.6e-18 66.3 0.0 1.2e-17 65.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP19006.1 - 2e-11 43.7 0.0 6.2e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CEP19006.1 - 0.0047 16.8 0.1 0.0084 16.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 CEP19006.1 - 0.029 14.6 0.1 0.059 13.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain PA PF02225.22 CEP19006.1 - 0.093 12.8 0.1 0.3 11.2 0.1 2.0 1 1 0 1 1 1 0 PA domain rve PF00665.26 CEP19007.1 - 2e-12 47.3 0.0 3.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP19007.1 - 4.7e-10 39.2 1.2 1e-09 38.1 1.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CEP19008.1 - 1.9e-09 37.4 0.0 3.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CEP19008.1 - 0.00037 20.6 0.2 0.00096 19.3 0.0 1.8 2 0 0 2 2 2 1 H2C2 zinc finger DUF35_N PF12172.8 CEP19010.1 - 0.13 12.2 1.6 0.22 11.4 1.6 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1775 PF07987.11 CEP19011.1 - 6.1e-27 94.7 0.1 1e-26 94.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) EF-hand_1 PF00036.32 CEP19014.1 - 3.7e-25 85.5 17.3 4.3e-08 32.2 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CEP19014.1 - 2.3e-21 76.0 7.6 1.1e-12 48.2 1.5 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP19014.1 - 4e-19 66.9 10.9 5.2e-05 22.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CEP19014.1 - 1.8e-16 58.8 18.4 1.4e-06 27.5 0.4 4.6 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 CEP19014.1 - 1.7e-12 47.0 14.0 1e-05 25.3 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEP19014.1 - 1.2e-06 28.8 0.1 0.012 16.0 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CEP19014.1 - 3e-05 23.9 9.4 0.0034 17.3 0.8 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CEP19014.1 - 0.0098 16.2 0.2 1.2 9.5 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain DUF4815 PF16075.5 CEP19014.1 - 0.054 11.8 0.1 0.076 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) Dockerin_1 PF00404.18 CEP19014.1 - 0.14 12.4 2.6 0.89 9.8 0.6 2.7 1 1 1 2 2 2 0 Dockerin type I domain Nse4-Nse3_bdg PF15412.6 CEP19014.1 - 0.6 10.3 5.3 6.1 7.0 0.6 3.5 3 1 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE AICARFT_IMPCHas PF01808.18 CEP19015.1 - 2e-93 313.1 0.1 3.8e-93 312.2 0.1 1.5 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CEP19015.1 - 7.4e-26 90.2 0.0 2.2e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain SET PF00856.28 CEP19018.1 - 2.2e-22 80.2 0.3 9e-22 78.2 0.3 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CEP19018.1 - 8.7e-15 55.3 4.2 8.7e-15 55.3 4.2 2.6 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.24 CEP19018.1 - 6.7e-08 32.3 0.1 1.5e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AWS PF17907.1 CEP19018.1 - 0.0079 16.2 3.6 0.027 14.5 3.6 1.9 1 0 0 1 1 1 1 AWS domain mRNA_cap_enzyme PF01331.19 CEP19019.1 - 3.4e-37 128.2 0.1 1.4e-20 74.0 0.0 2.5 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CEP19019.1 - 2.1e-18 66.9 0.0 2.1e-18 66.9 0.0 2.8 3 1 0 3 3 3 1 mRNA capping enzyme, C-terminal domain SMN PF06003.12 CEP19020.1 - 0.027 13.7 0.9 0.041 13.1 0.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) NNMT_PNMT_TEMT PF01234.17 CEP19020.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Caskin-Pro-rich PF16907.5 CEP19020.1 - 0.16 12.5 4.1 0.36 11.4 3.4 2.0 1 1 0 1 1 1 0 Proline rich region of Caskin proteins MULE PF10551.9 CEP19022.1 - 2.7e-06 27.7 1.3 6.9e-06 26.4 1.3 1.7 1 1 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 CEP19022.1 - 0.0058 17.3 0.7 0.015 16.0 0.7 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF753 PF05444.12 CEP19022.1 - 0.083 12.9 1.3 0.11 12.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF753) GTP_EFTU PF00009.27 CEP19024.1 - 5.6e-35 120.6 10.6 2.6e-34 118.5 4.2 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CEP19024.1 - 8.1e-30 103.1 2.0 2.1e-29 101.7 2.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CEP19024.1 - 1.8e-10 40.9 0.5 6.5e-10 39.1 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CEP19024.1 - 4.6e-08 33.3 3.4 3.7e-05 24.0 0.0 3.9 3 0 0 3 3 3 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 CEP19024.1 - 9.9e-05 21.9 0.9 0.00031 20.3 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CEP19024.1 - 0.00019 21.0 1.6 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CEP19024.1 - 0.0026 17.7 5.6 0.024 14.6 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 CEP19024.1 - 0.0035 17.5 0.1 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CEP19024.1 - 0.0082 15.6 0.0 0.0082 15.6 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CEP19024.1 - 0.2 11.7 8.3 5.8 7.0 0.0 4.2 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.6 CEP19024.1 - 0.21 12.1 16.3 8.2 6.9 5.2 3.7 4 0 0 4 4 4 0 AAA domain GTP_EFTU_D4 PF14578.6 CEP19024.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.4 4 0 0 4 4 3 0 Elongation factor Tu domain 4 APG6_N PF17675.1 CEP19024.1 - 0.53 10.8 18.7 5.1 7.6 11.2 3.0 2 0 0 2 2 2 0 Apg6 coiled-coil region FAM60A PF15396.6 CEP19024.1 - 3.8 7.4 9.9 5.4 7.0 5.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A OmpH PF03938.14 CEP19024.1 - 4.6 7.6 25.2 0.44 10.9 10.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RPN2_C PF18004.1 CEP19024.1 - 8.1 6.3 17.8 0.39 10.6 10.1 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNase_P_p30 PF01876.16 CEP19025.1 - 1.3e-46 158.8 0.2 1.8e-46 158.3 0.2 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Tom37 PF10568.9 CEP19026.1 - 2.7e-24 85.9 0.4 2.7e-24 85.9 0.4 1.8 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 CEP19026.1 - 1.3e-20 74.0 0.2 1.5e-19 70.6 0.1 2.5 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 CEP19026.1 - 1e-11 44.5 0.0 3.4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP19026.1 - 0.00037 20.5 0.1 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_L27A PF00828.19 CEP19027.1 - 9e-20 71.7 0.2 1.5e-19 70.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ubiquitin PF00240.23 CEP19028.1 - 9.2e-37 124.6 3.7 7.2e-33 112.2 0.6 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 CEP19028.1 - 8.5e-17 60.8 2.6 5.9e-15 54.9 0.7 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CEP19028.1 - 5.1e-05 23.6 0.2 0.00023 21.5 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CEP19028.1 - 0.0047 16.8 0.0 0.0081 16.1 0.0 1.5 1 1 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CEP19028.1 - 0.011 16.1 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain UDP-g_GGTase PF06427.11 CEP19028.1 - 0.03 14.5 0.2 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF2407 PF10302.9 CEP19028.1 - 0.061 13.9 0.1 0.073 13.6 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CEP19028.1 - 0.087 12.9 2.8 7.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CEP19028.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 1 1 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Tash_PEST PF07708.11 CEP19028.1 - 0.7 10.1 11.9 2 8.7 1.5 3.0 3 0 0 3 3 3 0 Tash protein PEST motif Ebp2 PF05890.12 CEP19029.1 - 1.4e-81 274.0 29.5 1.4e-81 274.0 29.5 1.3 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 CCDC-167 PF15188.6 CEP19030.1 - 0.75 10.2 4.7 2.3 8.6 1.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 tRNA_m1G_MT PF01746.21 CEP19031.1 - 2.1e-23 83.0 0.2 4.6e-23 81.9 0.2 1.6 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4051 PF13260.6 CEP19032.1 - 0.00039 20.1 0.7 0.0005 19.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) Cyt_c_ox_IV PF12270.8 CEP19032.1 - 0.00044 20.4 0.0 0.00058 20.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV WBP-1 PF11669.8 CEP19032.1 - 0.039 14.6 2.0 0.15 12.7 1.9 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 TMEM51 PF15345.6 CEP19032.1 - 0.092 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 zf-H2C2_2 PF13465.6 CEP19033.1 - 5.3e-08 32.9 9.3 3.6e-07 30.3 0.3 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 CEP19033.1 - 0.00022 21.5 15.4 0.0033 17.8 1.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF4611 PF15387.6 CEP19033.1 - 0.0079 16.4 2.9 0.016 15.4 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Adeno_PIX PF03955.14 CEP19033.1 - 0.011 15.8 2.9 0.019 15.1 2.9 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) zf-C2H2_8 PF15909.5 CEP19033.1 - 0.012 15.9 1.0 2.5 8.4 0.1 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 CEP19033.1 - 0.049 14.5 1.0 0.049 14.5 1.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf_ZIC PF18366.1 CEP19033.1 - 6.5 6.9 10.7 14 5.8 0.6 3.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain Phostensin PF13914.6 CEP19033.1 - 7.4 7.2 7.9 5.3 7.7 5.6 2.0 2 1 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region NUC173 PF08161.12 CEP19034.1 - 2.4e-67 226.6 4.0 4.6e-64 215.8 0.1 4.3 5 0 0 5 5 5 2 NUC173 domain Abhydrolase_9_N PF15420.6 CEP19034.1 - 0.0052 16.8 0.1 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus NinG PF05766.12 CEP19034.1 - 0.059 13.3 2.6 0.41 10.6 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Jnk-SapK_ap_N PF09744.9 CEP19034.1 - 0.72 10.1 5.1 3.2 8.0 0.0 3.7 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 HMG_box_5 PF14887.6 CEP19034.1 - 1.4 8.9 4.1 0.54 10.3 0.4 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 ANAPC5 PF12862.7 CEP19035.1 - 2.9e-18 65.7 9.1 2.2e-14 53.3 1.1 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 CEP19035.1 - 1.3e-08 34.7 0.1 2.9e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 CEP19035.1 - 7.5e-05 22.9 0.1 0.35 11.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_C11 PF03415.14 CEP19035.1 - 1.7 7.9 7.0 1.4 8.2 0.1 2.6 3 0 0 3 3 3 0 Clostripain family FRG PF08867.11 CEP19036.1 - 0.095 13.7 0.9 0.27 12.2 0.1 2.0 2 0 0 2 2 2 0 FRG domain RT_RNaseH_2 PF17919.1 CEP19037.1 - 2e-36 124.0 0.0 7.6e-36 122.2 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP19037.1 - 5.7e-36 123.0 0.0 1.7e-35 121.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP19037.1 - 1.7e-28 99.6 0.2 3.4e-28 98.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP19037.1 - 6e-20 71.1 0.4 4.1e-19 68.4 0.1 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CEP19037.1 - 8.5e-20 71.1 0.0 7.4e-19 68.1 0.0 2.7 3 0 0 3 3 2 1 Integrase core domain gag-asp_proteas PF13975.6 CEP19037.1 - 7.2e-08 32.9 0.0 2.5e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP19037.1 - 1.5e-07 31.3 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CEP19037.1 - 4.3e-06 27.3 0.0 2.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 CEP19037.1 - 2.5e-05 24.1 3.0 5.5e-05 23.1 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.6 CEP19037.1 - 0.0004 20.1 0.1 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Peptidase_A2B PF12384.8 CEP19037.1 - 0.027 14.0 0.2 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Ty3 transposon peptidase DNA_pol_viral_C PF00336.18 CEP19037.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain zf-CCHC_5 PF14787.6 CEP19037.1 - 2.3 8.0 8.2 5.2 6.9 8.2 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger AIF-MLS PF14962.6 CEP19038.1 - 8.7 6.3 8.8 11 5.9 8.8 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Lipase_GDSL PF00657.22 CEP19039.1 - 5.8e-06 26.4 0.3 7.7e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP19039.1 - 0.00027 21.4 1.3 0.00054 20.4 1.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cas9_PI2 PF18070.1 CEP19039.1 - 0.19 12.5 1.9 0.35 11.6 1.4 1.8 1 1 0 1 1 1 0 CRISPR-Cas9 PI domain Fungal_trans PF04082.18 CEP19040.1 - 3.6e-39 134.4 0.2 8.1e-39 133.3 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP19040.1 - 9.4e-10 38.5 10.8 2.2e-09 37.3 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIL PF01843.19 CEP19041.1 - 1.3e-16 60.7 1.0 1.3e-16 60.7 1.0 1.5 2 0 0 2 2 2 1 DIL domain FPL PF09758.9 CEP19041.1 - 0.07 13.1 0.4 0.85 9.6 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein RAB3GAP2_N PF14655.6 CEP19041.1 - 0.078 12.2 0.0 0.082 12.2 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Myosin_head PF00063.21 CEP19042.1 - 9.9e-268 889.9 2.2 1.4e-267 889.3 2.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CEP19042.1 - 1e-14 52.9 37.2 2.2e-05 23.8 0.3 7.5 7 0 0 7 7 7 5 IQ calmodulin-binding motif DIL PF01843.19 CEP19042.1 - 2.5e-05 24.5 0.6 0.00015 22.0 0.0 2.7 2 0 0 2 2 2 1 DIL domain AAA_22 PF13401.6 CEP19042.1 - 0.021 15.1 0.5 0.094 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MPS2 PF17060.5 CEP19042.1 - 0.045 13.0 10.9 0.096 11.9 10.9 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 Fez1 PF06818.15 CEP19042.1 - 0.056 13.9 20.4 0.17 12.3 20.4 1.9 1 0 0 1 1 1 0 Fez1 TsaE PF02367.17 CEP19042.1 - 0.12 12.3 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_pol_3_Rpc31 PF11705.8 CEP19042.1 - 0.21 11.8 12.3 0.5 10.6 12.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_16 PF13191.6 CEP19042.1 - 0.35 11.2 0.0 0.35 11.2 0.0 2.6 2 1 0 2 2 1 0 AAA ATPase domain Tropomyosin_1 PF12718.7 CEP19042.1 - 1.2 9.3 22.7 3 8.0 22.7 1.7 1 0 0 1 1 1 0 Tropomyosin like Baculo_PEP_C PF04513.12 CEP19042.1 - 2.4 8.2 5.8 1.5 8.8 1.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 CEP19042.1 - 2.7 8.4 10.5 1.6 9.1 1.2 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CEP19042.1 - 4.2 7.9 34.4 0.066 13.7 22.8 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region CCDC-167 PF15188.6 CEP19042.1 - 9.3 6.7 17.8 2.8 8.3 7.7 3.6 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 FapA PF03961.13 CEP19042.1 - 9.4 4.7 8.6 18 3.8 8.6 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A WBP-1 PF11669.8 CEP19044.1 - 0.0053 17.4 1.4 0.067 13.8 0.0 2.8 2 0 0 2 2 2 1 WW domain-binding protein 1 DUF4834 PF16118.5 CEP19044.1 - 0.026 15.5 0.1 0.026 15.5 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SCIMP PF15050.6 CEP19044.1 - 0.033 14.7 0.6 0.18 12.3 0.4 2.5 1 1 0 1 1 1 0 SCIMP protein EphA2_TM PF14575.6 CEP19044.1 - 0.089 13.7 0.1 0.34 11.8 0.1 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YwiC PF14256.6 CEP19044.1 - 0.23 11.8 0.3 0.4 11.0 0.3 1.3 1 0 0 1 1 1 0 YwiC-like protein RCR PF12273.8 CEP19044.1 - 1.3 9.7 9.4 0.14 12.8 3.0 2.8 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MAP17 PF15807.5 CEP19044.1 - 4.7 7.5 5.3 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MLANA PF14991.6 CEP19044.1 - 7.4 6.9 5.9 5.2 7.4 0.2 3.3 2 1 0 2 2 2 0 Protein melan-A RRM_1 PF00076.22 CEP19046.1 - 1.5e-58 194.5 0.4 2.5e-17 62.5 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP19046.1 - 1.5e-06 28.2 0.1 0.65 10.1 0.0 4.2 4 1 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 CEP19046.1 - 0.00034 20.4 0.1 1.4 8.7 0.0 3.5 4 1 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 CEP19046.1 - 0.00099 18.7 0.0 0.23 11.0 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP19046.1 - 0.0011 19.0 7.0 2.6 8.1 0.1 4.2 3 1 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 CEP19046.1 - 0.0011 18.9 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Sec31 PF11549.8 CEP19046.1 - 0.1 12.5 0.5 0.29 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein transport protein SEC31 DbpA PF03880.15 CEP19046.1 - 0.11 12.5 0.3 1 9.4 0.2 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain RNA_bind PF08675.11 CEP19046.1 - 0.14 12.2 0.0 16 5.6 0.0 3.0 2 2 0 2 2 2 0 RNA binding domain Smg8_Smg9 PF10220.9 CEP19046.1 - 1.5 7.0 10.3 3.3 5.9 10.3 1.5 1 0 0 1 1 1 0 Smg8_Smg9 Zip PF02535.22 CEP19046.1 - 6.1 6.0 4.9 14 4.8 4.9 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF866 PF05907.13 CEP19047.1 - 8.8e-56 188.1 5.6 9.9e-56 188.0 5.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.6 CEP19047.1 - 2.3 8.3 6.4 5.1 7.2 6.4 1.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Methyltransf_31 PF13847.6 CEP19048.1 - 7.8e-11 42.0 0.0 9.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP19048.1 - 6.8e-06 26.7 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP19048.1 - 0.00016 22.2 0.0 0.00025 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19048.1 - 0.0017 18.2 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP19048.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CEP19048.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 CEP19048.1 - 0.0073 15.7 0.0 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CEP19048.1 - 0.012 16.4 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 CEP19048.1 - 0.037 13.2 0.1 2 7.5 0.2 2.2 1 1 1 2 2 2 0 N2227-like protein HA2 PF04408.23 CEP19049.1 - 1.2e-25 89.9 0.1 1.2e-25 89.9 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CEP19049.1 - 4.5e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CEP19049.1 - 8.9e-13 48.6 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CEP19049.1 - 5e-09 36.4 0.3 1.2e-08 35.1 0.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CEP19049.1 - 6.8e-07 29.2 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CEP19049.1 - 3.3e-05 23.7 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP19049.1 - 8.4e-05 22.9 0.0 0.00026 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEP19049.1 - 0.00035 19.7 0.1 0.00076 18.6 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CEP19049.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CEP19049.1 - 0.0058 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Microtub_bd PF16796.5 CEP19049.1 - 0.0096 15.9 0.2 0.57 10.1 0.0 2.7 3 0 0 3 3 3 1 Microtubule binding Flavi_DEAD PF07652.14 CEP19049.1 - 0.028 14.4 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 CEP19049.1 - 0.054 14.0 0.9 1.2 9.6 0.1 3.1 2 1 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 CEP19049.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CEP19049.1 - 0.095 12.7 0.2 1.9 8.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 CEP19049.1 - 0.16 11.6 0.3 0.5 10.0 0.3 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RRM_1 PF00076.22 CEP19050.1 - 1.1e-10 41.2 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CEP19050.1 - 0.076 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HGTP_anticodon2 PF12745.7 CEP19050.1 - 5.7 6.4 12.2 2.9 7.3 0.1 3.1 3 0 0 3 3 3 0 Anticodon binding domain of tRNAs Sod_Cu PF00080.20 CEP19051.1 - 6.2e-50 169.1 4.0 7.5e-50 168.8 4.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) NAD_binding_10 PF13460.6 CEP19052.1 - 9.9e-09 35.3 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CEP19052.1 - 1.3e-07 31.3 0.1 6.4e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CEP19052.1 - 2.5e-06 27.2 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CEP19052.1 - 1.5e-05 24.2 0.0 0.0001 21.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CEP19052.1 - 0.00024 20.4 0.0 0.018 14.3 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein TrkA_N PF02254.18 CEP19052.1 - 0.084 13.1 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 CEP19053.1 - 1.9e-52 178.2 0.0 4.7e-38 131.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19053.1 - 1.4e-18 67.1 0.0 2.6e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP19053.1 - 4.9e-07 29.3 0.1 7.4e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP19053.1 - 3.5e-06 26.5 0.0 6.8e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CEP19053.1 - 0.00035 20.6 0.0 0.00049 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP19053.1 - 0.0012 17.9 0.1 0.038 12.9 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 CEP19053.1 - 0.0076 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CEP19053.1 - 0.14 10.9 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Y_phosphatase PF00102.27 CEP19054.1 - 8e-68 228.5 0.3 8e-68 228.5 0.3 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CEP19054.1 - 6e-06 26.1 0.2 4.1e-05 23.4 0.0 2.4 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CEP19054.1 - 8.2e-05 22.7 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CEP19054.1 - 9.7e-05 22.5 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Myotub-related PF06602.14 CEP19054.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Mito_carr PF00153.27 CEP19055.1 - 4.9e-57 189.8 10.9 2.2e-22 78.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP19055.1 - 5e-05 22.6 3.7 0.01 15.0 3.7 3.0 1 1 0 1 1 1 1 Gammaproteobacterial serine protease SpoVAD PF07451.11 CEP19055.1 - 0.012 14.3 0.2 0.02 13.6 0.2 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) RSN1_7TM PF02714.15 CEP19055.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.7 1 1 1 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Ribosomal_L30_N PF08079.12 CEP19056.1 - 9.4e-22 77.1 9.3 1.6e-21 76.3 9.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CEP19056.1 - 5.9e-18 64.5 1.0 5.9e-18 64.5 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF3157 PF11355.8 CEP19056.1 - 0.027 14.1 0.6 0.047 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Amidinotransf PF02274.17 CEP19056.1 - 0.092 11.8 0.3 0.16 11.1 0.3 1.3 1 0 0 1 1 1 0 Amidinotransferase CarD_CdnL_TRCF PF02559.16 CEP19056.1 - 0.17 12.6 4.2 0.41 11.4 1.6 2.4 2 1 0 2 2 2 0 CarD-like/TRCF domain Arf PF00025.21 CEP19057.1 - 7.8e-80 266.4 0.1 8.9e-80 266.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP19057.1 - 5.4e-14 52.4 0.0 7.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEP19057.1 - 4.1e-13 49.2 1.3 3.8e-09 36.2 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CEP19057.1 - 6.3e-13 48.6 0.0 7.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEP19057.1 - 9.3e-13 48.1 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEP19057.1 - 2.2e-10 40.3 0.0 2.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP19057.1 - 7.5e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEP19057.1 - 0.0052 16.1 0.3 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TPR_2 PF07719.17 CEP19058.1 - 8.4e-10 38.0 19.4 0.1 12.8 0.1 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19058.1 - 2.4e-09 36.6 7.3 0.37 10.7 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP19058.1 - 2.7e-08 33.4 1.6 0.19 11.4 0.2 5.4 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 CEP19058.1 - 2.7e-07 31.0 8.1 0.0047 17.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CEP19058.1 - 5.5e-06 26.6 0.4 0.0031 17.8 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CEP19058.1 - 2e-05 24.7 1.2 0.28 11.7 0.0 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19058.1 - 0.00017 21.6 15.9 2.6 8.5 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 CEP19058.1 - 0.00031 21.1 3.5 7.9 7.4 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEP19058.1 - 0.0027 18.0 4.9 1.8 8.9 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP19058.1 - 0.011 15.9 11.2 1.2 9.4 0.0 5.6 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CEP19058.1 - 0.041 13.9 7.4 1.1 9.4 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19058.1 - 0.11 13.3 28.0 0.74 10.8 0.0 7.3 6 2 3 9 9 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CEP19058.1 - 0.18 11.9 2.0 40 4.2 0.0 4.0 4 0 0 4 4 4 0 Putative TPR-like repeat TPR_10 PF13374.6 CEP19058.1 - 0.39 10.7 14.8 1.5 8.8 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP19058.1 - 3.4 8.4 24.0 16 6.3 0.0 7.0 5 3 4 9 9 9 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 CEP19059.1 - 8.7e-37 125.1 7.5 3.5e-13 49.5 0.7 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP19059.1 - 6.5e-28 96.8 6.4 1.2e-11 44.6 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CEP19059.1 - 6e-05 23.4 4.5 0.15 12.5 0.1 3.9 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEP19059.1 - 0.00084 19.2 0.0 0.15 12.0 0.0 2.5 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 CEP19059.1 - 0.0058 16.6 0.0 0.45 10.6 0.0 2.7 2 1 1 3 3 3 1 SLIDE Rap1_C PF11626.8 CEP19059.1 - 0.024 14.7 0.0 7.5 6.7 0.0 2.9 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribosomal_L5e PF17144.4 CEP19061.1 - 1.7e-82 275.3 0.1 2.9e-82 274.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CEP19061.1 - 7.4e-28 97.3 3.1 7.4e-28 97.3 3.1 2.1 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region PhoD PF09423.10 CEP19061.1 - 6e-06 25.5 0.0 0.00029 20.0 0.0 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase UCH PF00443.29 CEP19062.1 - 4.2e-32 111.6 0.4 6.4e-32 111.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Casc1 PF12366.8 CEP19062.1 - 0.044 13.3 0.1 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Ras PF00071.22 CEP19063.1 - 4.4e-47 159.7 0.5 7e-47 159.0 0.5 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CEP19063.1 - 6.2e-15 55.5 0.1 7e-14 52.1 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP19063.1 - 0.00018 21.0 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP19063.1 - 0.00032 20.3 1.0 0.00066 19.3 0.3 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CEP19063.1 - 0.0015 18.5 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase DUF2951 PF11166.8 CEP19063.1 - 0.17 12.1 3.6 0.071 13.3 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4604 PF15377.6 CEP19063.1 - 0.18 12.2 6.6 0.57 10.6 6.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Sulfotransfer_4 PF17784.1 CEP19064.1 - 5.9e-56 189.7 0.0 7.3e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CEP19064.1 - 4.6e-06 27.2 0.4 0.00058 20.3 0.1 2.4 1 1 1 2 2 2 2 Sulfotransferase family GSCFA PF08885.11 CEP19064.1 - 0.0048 16.6 0.0 0.65 9.6 0.0 2.3 1 1 1 2 2 2 2 GSCFA family EntA_Immun PF08951.10 CEP19064.1 - 0.13 12.6 0.6 0.54 10.7 0.0 2.3 3 0 0 3 3 3 0 Enterocin A Immunity Mcp5_PH PF12814.7 CEP19065.1 - 4.4e-28 97.8 0.8 4.4e-28 97.8 0.8 2.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CEP19065.1 - 8.9e-06 26.2 2.8 1.7e-05 25.3 1.3 2.4 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 CEP19065.1 - 0.013 15.8 3.2 0.022 15.1 0.0 2.9 2 1 0 2 2 2 0 Plant pleckstrin homology-like region FixH PF05751.11 CEP19065.1 - 0.073 13.1 1.6 0.21 11.6 1.3 2.0 1 1 0 1 1 1 0 FixH PH_11 PF15413.6 CEP19065.1 - 3.8 8.0 9.2 0.7 10.3 0.1 4.0 2 1 0 2 2 2 0 Pleckstrin homology domain Ecl1 PF12855.7 CEP19066.1 - 7.3e-10 40.3 2.7 7.8e-10 40.2 2.7 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CEP19066.1 - 0.058 13.5 0.9 0.058 13.5 0.9 1.6 2 0 0 2 2 2 0 MYND finger HA2 PF04408.23 CEP19067.1 - 2.6e-17 63.0 0.0 7.5e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CEP19067.1 - 1.8e-15 57.3 0.1 5.6e-15 55.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CEP19067.1 - 1.9e-14 53.8 0.0 4.1e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 CEP19067.1 - 2.2e-14 53.7 1.2 5.8e-14 52.4 1.2 1.8 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 CEP19067.1 - 7.1e-08 32.4 0.6 1.9e-07 31.0 0.6 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 CEP19067.1 - 0.0013 18.9 0.0 0.0069 16.6 0.0 2.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 CEP19067.1 - 0.0094 16.2 1.2 0.025 14.8 0.4 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CEP19067.1 - 0.021 15.1 0.2 0.046 14.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CEP19067.1 - 0.042 13.2 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 KaiC UBA PF00627.31 CEP19067.1 - 0.042 13.8 0.0 0.16 11.9 0.0 2.1 1 0 0 1 1 1 0 UBA/TS-N domain T2SSE PF00437.20 CEP19067.1 - 0.043 12.9 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PG_binding_2 PF08823.11 CEP19067.1 - 0.056 13.8 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DsbG_N PF18257.1 CEP19067.1 - 0.33 11.1 0.0 0.33 11.1 0.0 2.4 3 0 0 3 3 2 0 Disulfide isomerase DsbG N-terminal HLH PF00010.26 CEP19068.1 - 2.4e-16 59.4 4.5 2.4e-16 59.4 4.5 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KAP_NTPase PF07693.14 CEP19068.1 - 0.058 12.6 1.0 0.091 12.0 1.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain HlyD_2 PF12700.7 CEP19068.1 - 0.35 9.6 5.1 0.45 9.2 5.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Mito_carr PF00153.27 CEP19069.1 - 4e-67 222.2 2.5 5.6e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SQS_PSY PF00494.19 CEP19071.1 - 9.9e-35 120.3 0.0 1.2e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RIX1 PF08167.12 CEP19072.1 - 1e-45 155.8 4.5 1e-45 155.8 4.5 3.0 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis TP_methylase PF00590.20 CEP19073.1 - 1.7e-41 142.5 0.0 2.6e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CEP19073.1 - 3.5e-29 101.3 0.1 1.4e-28 99.4 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CEP19073.1 - 3.3e-14 52.2 4.0 4.1e-14 52.0 2.9 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CEP19073.1 - 5.5e-12 44.9 0.1 1.3e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central AlaDh_PNT_C PF01262.21 CEP19073.1 - 0.02 14.2 0.6 0.06 12.6 0.7 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain OTCace PF00185.24 CEP19073.1 - 0.081 13.0 0.0 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Pyr_redox_3 PF13738.6 CEP19073.1 - 0.085 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CEP19073.1 - 0.1 12.0 0.2 0.24 10.7 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 CEP19073.1 - 0.17 11.2 0.1 0.35 10.2 0.0 1.9 1 1 1 2 2 2 0 ThiF family GTP_EFTU PF00009.27 CEP19074.1 - 6.8e-61 205.2 0.1 1e-60 204.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CEP19074.1 - 1.5e-39 134.5 0.0 4.4e-39 133.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CEP19074.1 - 5.5e-30 103.3 0.0 1.4e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CEP19074.1 - 1.6e-26 92.1 0.1 3.9e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CEP19074.1 - 2.4e-11 43.8 0.1 6.4e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CEP19074.1 - 4.4e-06 26.6 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CEP19074.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CEP19074.1 - 0.045 13.1 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AbfS_sensor PF18225.1 CEP19074.1 - 0.061 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain LRR_4 PF12799.7 CEP19075.1 - 0.00087 19.6 6.6 0.59 10.6 0.3 5.2 5 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CEP19075.1 - 0.39 10.5 3.3 1.2 9.0 0.8 3.1 3 1 0 3 3 3 0 Leucine rich repeat Phi_1 PF04674.12 CEP19076.1 - 4.3e-30 105.0 0.1 7e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region MASE3 PF17159.4 CEP19077.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated sensor domain CrgA PF06781.12 CEP19077.1 - 1.2 9.2 3.2 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Cell division protein CrgA DUF4407 PF14362.6 CEP19077.1 - 6.6 6.0 6.8 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Arf PF00025.21 CEP19078.1 - 1.7e-54 183.9 2.2 1.8e-54 183.9 0.9 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family CotH PF08757.11 CEP19078.1 - 2.3e-34 119.4 8.0 3.1e-28 99.3 2.0 2.4 1 1 1 2 2 2 2 CotH kinase protein Roc PF08477.13 CEP19078.1 - 1.3e-14 54.4 1.7 2.7e-14 53.4 0.6 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP19078.1 - 7.1e-12 45.2 0.5 1.5e-11 44.2 0.5 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEP19078.1 - 4.1e-11 42.7 0.5 7.9e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEP19078.1 - 2.2e-09 36.9 1.8 4.4e-07 29.4 0.2 2.8 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CEP19078.1 - 9.8e-08 32.1 0.2 2.1e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CEP19078.1 - 4e-06 26.4 0.5 4e-06 26.4 0.5 2.1 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CEP19078.1 - 0.0087 15.6 1.9 0.025 14.1 1.9 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 CEP19078.1 - 0.014 15.4 0.7 0.075 13.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CEP19078.1 - 0.053 13.1 0.6 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_S24e PF01282.19 CEP19079.1 - 1.6e-36 124.1 0.1 2.8e-36 123.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e DIM1 PF02966.16 CEP19079.1 - 0.0089 15.8 0.3 0.024 14.4 0.2 1.8 1 1 0 1 1 1 1 Mitosis protein DIM1 Zip PF02535.22 CEP19080.1 - 1.3e-66 225.2 8.1 2e-66 224.5 8.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2160 PF09928.9 CEP19080.1 - 0.14 12.5 0.8 0.43 10.9 0.1 2.2 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2160) Tir_receptor_C PF07489.11 CEP19081.1 - 0.045 13.7 2.6 0.052 13.5 2.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Methyltransf_4 PF02390.17 CEP19082.1 - 3.7e-60 202.3 0.0 4.6e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CEP19082.1 - 0.00084 20.0 0.0 0.0017 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP19082.1 - 0.0032 17.1 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CEP19082.1 - 0.037 13.8 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CEP19082.1 - 0.088 13.6 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CEP19082.1 - 0.2 12.3 0.0 0.5 11.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Rieske PF00355.26 CEP19083.1 - 5.5e-06 26.2 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Acetyltransf_10 PF13673.7 CEP19084.1 - 4.2e-08 33.2 0.1 1.3e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CEP19084.1 - 1.9e-07 31.3 0.0 3.2e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP19084.1 - 9.9e-07 29.1 0.0 2.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP19084.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CEP19084.1 - 3.9e-05 23.7 0.0 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CEP19084.1 - 0.1 12.8 0.0 0.55 10.4 0.0 2.1 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CEP19084.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SAM_Ste50p PF09235.10 CEP19084.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif CNH PF00780.22 CEP19085.1 - 4.4e-55 187.2 0.0 7.2e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP19085.1 - 1.3e-32 113.5 2.2 4.3e-32 111.8 2.2 2.0 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP19085.1 - 1.5e-16 60.7 3.4 6.8e-16 58.6 0.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CEP19085.1 - 0.0057 17.2 0.0 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 CEP19085.1 - 0.023 14.5 0.0 0.023 14.5 0.0 2.7 3 1 0 3 3 3 0 Pleckstrin homology domain PAS_9 PF13426.7 CEP19086.1 - 7.9e-24 83.9 0.0 2.8e-16 59.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 CEP19086.1 - 2.7e-20 72.5 0.0 2.8e-12 46.7 0.0 4.0 4 0 0 4 4 4 3 PAS fold GATA PF00320.27 CEP19086.1 - 2.2e-15 56.0 3.0 4.7e-15 54.9 3.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 CEP19086.1 - 1.3e-12 47.9 0.0 1.6e-05 25.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 CEP19086.1 - 5.3e-09 36.1 0.0 0.0044 17.0 0.0 3.9 3 1 0 3 3 3 2 PAS fold PAS_11 PF14598.6 CEP19086.1 - 2e-07 31.1 0.0 8.5e-05 22.6 0.0 3.4 4 0 0 4 4 4 1 PAS domain DUF4763 PF15960.5 CEP19086.1 - 0.0064 15.8 0.7 0.013 14.8 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Pkinase PF00069.25 CEP19087.1 - 4.8e-64 216.3 0.0 5.6e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19087.1 - 3.5e-27 95.3 0.0 4.9e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CEP19087.1 - 0.00097 18.5 0.4 0.0022 17.4 0.4 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP19087.1 - 0.0025 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP19087.1 - 0.0049 15.9 0.5 0.0095 14.9 0.5 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CEP19087.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RelB PF04221.12 CEP19087.1 - 0.17 11.8 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 RelB antitoxin Fes1 PF08609.10 CEP19088.1 - 2e-21 76.7 1.5 2e-21 76.7 1.5 2.2 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 CEP19088.1 - 8.3e-08 31.9 0.0 0.0043 17.2 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 CEP19088.1 - 4.7e-06 26.4 0.0 0.0087 16.1 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CEP19088.1 - 2e-05 24.9 0.0 0.002 18.4 0.0 3.3 2 1 3 5 5 5 3 HEAT repeats Adaptin_N PF01602.20 CEP19088.1 - 0.0001 21.1 1.1 0.03 12.9 0.2 2.8 1 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 CEP19088.1 - 0.00014 21.9 0.0 0.00056 20.0 0.0 2.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Clathrin PF00637.20 CEP19088.1 - 0.0015 18.4 1.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS HEAT_EZ PF13513.6 CEP19088.1 - 0.0053 17.2 0.0 0.1 13.1 0.0 2.8 1 1 1 2 2 2 1 HEAT-like repeat V-ATPase_H_C PF11698.8 CEP19088.1 - 0.0076 16.3 1.1 2.7 8.1 0.0 3.1 1 1 1 3 3 3 1 V-ATPase subunit H Nop52 PF05997.12 CEP19088.1 - 0.25 11.1 1.6 1.7 8.4 0.0 2.4 2 1 1 3 3 3 0 Nucleolar protein,Nop52 MRP-S26 PF14943.6 CEP19091.1 - 0.0031 17.5 17.1 0.0031 17.5 17.1 1.7 1 1 0 1 1 1 1 Mitochondrial ribosome subunit S26 SID-1_RNA_chan PF13965.6 CEP19091.1 - 0.55 8.6 1.5 0.54 8.6 1.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Homeobox_KN PF05920.11 CEP19092.1 - 1e-18 66.9 2.0 1e-18 66.9 2.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 CEP19092.1 - 6.4e-08 32.3 0.4 1.5e-07 31.1 0.4 1.7 1 0 0 1 1 1 1 Homeodomain BTB_2 PF02214.22 CEP19093.1 - 1.2e-14 54.3 1.9 1.5e-14 54.1 0.5 1.8 2 0 0 2 2 2 1 BTB/POZ domain RFC1 PF08519.12 CEP19093.1 - 0.0064 16.7 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain CNH PF00780.22 CEP19094.1 - 1.3e-61 208.6 0.0 5.1e-61 206.7 0.0 2.1 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP19094.1 - 1.1e-37 130.1 1.4 5.5e-37 127.8 0.9 2.5 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 CEP19094.1 - 7.2e-30 103.8 0.9 5e-29 101.1 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 CEP19094.1 - 4e-14 52.4 0.1 9e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SR-25 PF10500.9 CEP19094.1 - 9.3e-14 51.6 12.0 9.3e-14 51.6 12.0 5.1 4 2 0 5 5 5 1 Nuclear RNA-splicing-associated protein DSPc PF00782.20 CEP19095.1 - 6e-39 132.9 0.1 1.4e-25 89.6 0.1 2.8 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP19095.1 - 3e-05 23.7 0.0 0.011 15.3 0.2 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CEP19095.1 - 6.6e-05 23.2 0.1 1.3 9.3 0.0 3.3 3 0 0 3 3 3 2 Rit1 DUSP-like domain BCL9 PF11502.8 CEP19095.1 - 0.0075 16.0 0.6 0.037 13.8 0.1 2.2 2 0 0 2 2 2 1 B-cell lymphoma 9 protein PTPlike_phytase PF14566.6 CEP19095.1 - 0.067 13.3 0.1 0.33 11.1 0.1 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 CEP19095.1 - 0.092 12.4 1.6 15 5.2 0.0 2.9 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HSP70 PF00012.20 CEP19096.1 - 4.7e-09 35.0 0.0 1.4e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP19096.1 - 0.11 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Piwi PF02171.17 CEP19097.1 - 1.1e-96 323.7 0.0 1.4e-96 323.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CEP19097.1 - 5.9e-25 88.5 0.0 1.1e-24 87.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CEP19097.1 - 4.4e-17 61.5 0.0 1.1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 CEP19097.1 - 3.3e-15 56.1 0.0 6.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CEP19097.1 - 2.6e-13 50.1 0.0 8e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CEP19097.1 - 1.7e-08 34.6 0.0 5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Band_7 PF01145.25 CEP19098.1 - 1.5e-23 83.7 4.9 2.3e-23 83.1 4.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 CEP19098.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Forkhead PF00250.18 CEP19099.1 - 1.6e-34 118.1 0.1 4e-34 116.7 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain Kelch_4 PF13418.6 CEP19100.1 - 7.2e-12 45.1 1.9 0.022 14.7 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CEP19100.1 - 2.3e-09 37.0 4.3 0.1 12.6 0.0 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CEP19100.1 - 7e-06 26.2 6.3 0.00073 19.8 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP19100.1 - 0.00014 22.0 3.0 2.5 8.5 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CEP19100.1 - 0.00081 19.3 3.3 0.29 11.2 0.0 4.4 4 1 0 4 4 4 1 Kelch motif OAD_gamma PF04277.13 CEP19100.1 - 0.025 15.2 0.0 0.053 14.1 0.0 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEM154 PF15102.6 CEP19100.1 - 0.031 14.2 0.2 0.073 13.0 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family ASFV_J13L PF05568.11 CEP19100.1 - 0.083 12.6 0.5 0.19 11.5 0.5 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4604 PF15377.6 CEP19102.1 - 4.5e-08 33.7 26.9 1.2e-07 32.3 26.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2944 PF11161.8 CEP19102.1 - 0.09 12.7 0.8 0.64 9.9 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2946) CDC45 PF02724.14 CEP19102.1 - 7.5 4.7 15.5 8.7 4.5 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein TPR_2 PF07719.17 CEP19103.1 - 7.2e-24 81.9 11.1 0.021 14.9 0.0 11.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19103.1 - 1.5e-23 81.6 6.0 0.013 15.3 0.0 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 CEP19103.1 - 1.8e-22 79.6 10.4 2.1e-07 31.3 0.4 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEP19103.1 - 3.8e-19 67.6 4.6 0.0086 16.4 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19103.1 - 4.6e-19 67.0 11.8 0.027 14.7 0.0 11.1 9 1 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 CEP19103.1 - 9.6e-18 64.6 1.2 0.013 16.1 0.0 6.2 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 CEP19103.1 - 3.1e-15 55.7 12.4 0.0047 17.5 0.1 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 CEP19103.1 - 6.7e-15 55.1 13.1 5e-05 23.5 0.2 8.1 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CEP19103.1 - 4.1e-14 52.0 3.5 0.0012 18.5 0.0 6.3 6 0 0 6 6 6 3 TPR repeat TPR_7 PF13176.6 CEP19103.1 - 1.7e-13 49.6 12.3 0.00025 20.9 0.1 8.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19103.1 - 8.8e-11 41.7 11.0 0.048 14.5 0.1 9.0 5 2 5 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CEP19103.1 - 1e-08 35.2 0.0 0.05 13.8 0.0 5.0 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP19103.1 - 8.8e-08 31.8 4.4 0.0013 18.6 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 CEP19103.1 - 1.9e-06 28.1 3.4 0.1 13.0 0.7 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP19103.1 - 1.9e-05 24.8 7.8 0.21 11.8 0.2 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CEP19103.1 - 9.8e-05 21.9 1.2 0.041 13.3 0.3 3.0 2 0 0 2 2 2 2 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 CEP19103.1 - 0.00013 22.4 6.0 0.95 9.9 0.2 5.0 3 2 2 5 5 5 2 Alkyl sulfatase dimerisation Vps39_1 PF10366.9 CEP19103.1 - 0.00033 20.9 3.7 2.5 8.4 0.0 4.8 4 0 0 4 4 3 2 Vacuolar sorting protein 39 domain 1 Flagellin_N PF00669.20 CEP19103.1 - 0.0088 16.2 1.5 0.0088 16.2 1.5 3.7 4 1 1 5 5 3 1 Bacterial flagellin N-terminal helical region Wzy_C_2 PF11846.8 CEP19103.1 - 0.11 12.4 2.2 0.72 9.8 0.0 2.9 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Peptidase_M28 PF04389.17 CEP19104.1 - 4.4e-45 153.8 0.0 9.8e-45 152.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CEP19104.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CEP19104.1 - 0.00098 18.2 0.0 0.0041 16.2 0.0 2.0 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase CobS PF02654.15 CEP19104.1 - 0.01 16.0 2.9 0.01 16.0 2.9 2.6 3 0 0 3 3 3 0 Cobalamin-5-phosphate synthase Aa_trans PF01490.18 CEP19105.1 - 1.7e-93 313.5 37.2 2.1e-93 313.3 37.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0176_N PF17773.1 CEP19106.1 - 9.6e-19 67.5 0.0 2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 CEP19106.1 - 7.7e-15 55.0 11.6 7.7e-15 55.0 11.6 1.8 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 CEP19106.1 - 3.4e-06 27.5 0.0 7.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.6 CEP19106.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ta0938 PF11494.8 CEP19106.1 - 0.32 11.3 2.5 0.67 10.3 2.5 1.5 1 0 0 1 1 1 0 Ta0938 Myb_DNA-binding PF00249.31 CEP19107.1 - 2.2e-40 136.6 8.0 1.4e-15 57.2 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP19107.1 - 2.6e-32 110.8 9.0 2.5e-16 59.6 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CEP19107.1 - 0.00018 21.3 0.5 0.21 11.5 0.0 3.2 4 0 0 4 4 4 2 Myb DNA-binding like Rap1_C PF11626.8 CEP19107.1 - 0.00082 19.4 0.0 2.6 8.2 0.0 3.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 CEP19107.1 - 0.0035 17.3 0.1 0.97 9.5 0.0 3.7 2 1 2 4 4 4 1 SLIDE Myb_DNA-bind_4 PF13837.6 CEP19107.1 - 0.0079 16.6 10.8 3.6 8.0 2.0 4.2 2 2 1 3 3 3 2 Myb/SANT-like DNA-binding domain MFS_1 PF07690.16 CEP19108.1 - 1.4e-60 205.1 40.0 3.8e-53 180.7 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP19108.1 - 3.6e-15 55.8 20.3 9.5e-11 41.2 6.3 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 CEP19108.1 - 0.00011 20.6 12.0 0.0059 15.0 7.3 2.9 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1218 PF06749.12 CEP19108.1 - 0.67 10.5 4.9 0.47 11.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Peptidase_S8 PF00082.22 CEP19109.1 - 2.6e-39 135.3 8.3 4.2e-39 134.6 8.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CEP19109.1 - 0.0039 17.8 0.2 0.0076 16.9 0.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyridoxal_deC PF00282.19 CEP19110.1 - 1.4e-74 251.1 0.0 1.9e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IMPDH PF00478.25 CEP19111.1 - 5e-133 443.4 5.0 5.9e-133 443.1 5.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CEP19111.1 - 2e-16 60.1 0.2 8.8e-09 35.7 0.1 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CEP19111.1 - 3.9e-11 42.6 1.5 3.5e-10 39.4 0.9 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CEP19111.1 - 9.2e-06 25.3 3.3 0.0019 17.7 0.2 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 CEP19111.1 - 6e-05 22.6 6.5 0.0018 17.7 5.0 2.5 2 1 1 3 3 3 1 Nitronate monooxygenase ThiG PF05690.14 CEP19111.1 - 0.00016 21.1 1.4 0.00087 18.7 0.2 2.3 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 CEP19111.1 - 0.002 17.3 0.2 0.0043 16.3 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 CEP19111.1 - 0.0034 16.3 0.0 0.0076 15.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Dus PF01207.17 CEP19111.1 - 0.01 14.9 1.8 2.3 7.3 0.0 2.4 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 CEP19111.1 - 0.011 15.1 0.5 5.2 6.4 0.1 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Aldolase PF01081.19 CEP19111.1 - 0.053 12.9 1.1 0.089 12.2 0.1 1.8 2 0 0 2 2 2 0 KDPG and KHG aldolase RRM_1 PF00076.22 CEP19112.1 - 1.3e-22 79.4 9.9 7.1e-16 57.8 0.1 4.6 4 1 1 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CEP19112.1 - 7.1e-08 32.5 0.0 8.6e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CEP19112.1 - 1e-06 28.6 0.1 0.26 11.1 0.0 3.6 2 1 2 4 4 4 3 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CEP19112.1 - 0.018 15.0 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mgm101p PF06420.12 CEP19113.1 - 3.3e-87 290.3 0.0 5.1e-87 289.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Cullin_binding PF03556.15 CEP19113.1 - 0.017 15.6 0.3 0.027 14.9 0.3 1.3 1 0 0 1 1 1 0 Cullin binding KIP1 PF07765.12 CEP19113.1 - 0.093 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 KIP1-like protein Autophagy_C PF10381.9 CEP19113.1 - 0.78 9.3 2.7 1.3 8.6 2.7 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Peptidase_M24 PF00557.24 CEP19114.1 - 2.9e-54 183.9 0.1 3.5e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CEP19114.1 - 2.5e-16 59.7 6.5 5.8e-16 58.5 6.5 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CEP19114.1 - 0.0027 17.8 2.8 0.0067 16.5 2.8 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 CEP19114.1 - 1.8 8.5 5.1 5 7.1 5.1 1.8 1 0 0 1 1 1 0 HIT zinc finger DUF3419 PF11899.8 CEP19116.1 - 1.1e-135 452.7 0.2 1.8e-135 452.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 CEP19116.1 - 5e-10 39.9 0.0 2.9e-08 34.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19116.1 - 7.9e-09 35.6 0.0 3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP19116.1 - 1.6e-08 35.1 0.0 8.9e-06 26.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP19116.1 - 1.5e-07 31.3 0.0 1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP19116.1 - 8.5e-07 29.6 0.0 5.9e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP19116.1 - 1.7e-06 27.6 0.0 4.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CEP19116.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 CEP19116.1 - 0.0024 17.4 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 CEP19116.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF962 PF06127.11 CEP19116.1 - 0.066 13.3 3.9 0.07 13.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF962) Homeodomain PF00046.29 CEP19117.1 - 2.3e-06 27.4 1.1 5.5e-06 26.1 1.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP19117.1 - 0.046 13.6 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Homeobox KN domain CDC45 PF02724.14 CEP19117.1 - 0.088 11.1 9.3 0.13 10.6 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2946 PF11162.8 CEP19117.1 - 0.45 11.2 9.9 5.5 7.7 3.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) DNA_pol_phi PF04931.13 CEP19117.1 - 8.9 4.3 11.5 14 3.6 11.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Lipase_GDSL PF00657.22 CEP19118.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF1949 PF09186.11 CEP19118.1 - 0.096 12.6 0.3 0.31 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) MFS_1 PF07690.16 CEP19119.1 - 1.2e-34 119.8 29.6 6.4e-21 74.7 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP19119.1 - 4.5e-05 22.5 1.7 4.5e-05 22.5 1.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter UPF0242 PF06785.11 CEP19119.1 - 0.038 14.1 2.3 0.11 12.6 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1464 PF07318.12 CEP19119.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) GST_C_3 PF14497.6 CEP19121.1 - 1.8e-17 63.4 0.1 3.1e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP19121.1 - 7.7e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEP19121.1 - 0.00033 21.0 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP19121.1 - 0.00097 19.4 0.0 0.0027 18.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEP19121.1 - 0.0027 17.7 0.0 0.0094 16.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CEP19121.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_N_2 PF13409.6 CEP19121.1 - 0.15 12.4 0.0 1.2 9.5 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Las1 PF04031.13 CEP19122.1 - 1.3e-50 171.5 0.9 2.2e-50 170.7 0.9 1.4 1 0 0 1 1 1 1 Las1-like PI3K_P85_iSH2 PF16454.5 CEP19123.1 - 0.0005 19.7 6.2 0.0011 18.6 1.5 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_11 PF13414.6 CEP19123.1 - 0.0039 16.8 1.1 0.39 10.4 0.1 3.2 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 CEP19123.1 - 0.0043 17.3 0.4 13 6.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19123.1 - 0.02 14.7 6.4 2.3 8.2 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19123.1 - 0.022 15.5 2.5 20 6.3 0.2 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat Spectrin PF00435.21 CEP19123.1 - 0.031 14.8 5.1 0.19 12.3 1.4 2.8 2 0 0 2 2 2 0 Spectrin repeat TPR_2 PF07719.17 CEP19123.1 - 0.037 14.1 4.9 6.5 7.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CEP19123.1 - 0.52 10.9 4.9 31 5.2 0.0 4.2 5 2 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 CEP19123.1 - 0.7 10.0 13.8 1.7 8.8 0.2 4.5 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain Spore_III_AB PF09548.10 CEP19123.1 - 2.4 8.2 9.2 4.2 7.5 2.3 3.2 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SASA PF03629.18 CEP19124.1 - 6e-55 186.3 0.1 3.1e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate esterase, sialic acid-specific acetylesterase G-alpha PF00503.20 CEP19125.1 - 7.5e-52 176.6 0.0 1.7e-51 175.5 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP19125.1 - 3.7e-07 29.8 0.1 5.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Radical_SAM PF04055.21 CEP19126.1 - 4.6e-33 115.0 0.1 1.7e-32 113.1 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 CEP19126.1 - 1e-22 80.0 0.6 2e-21 75.9 0.0 2.5 1 1 1 2 2 2 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 CEP19126.1 - 7e-05 22.7 0.2 7e-05 22.7 0.2 1.8 2 0 0 2 2 2 1 TRAM domain TRAM_2 PF18693.1 CEP19126.1 - 0.035 14.3 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 TRAM domain Complex1_LYR PF05347.15 CEP19127.1 - 9.4e-05 22.4 0.2 0.00025 21.0 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) bZIP_1 PF00170.21 CEP19128.1 - 3e-09 36.9 15.5 8.4e-09 35.4 15.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 CEP19128.1 - 8.8e-07 29.0 0.2 8.8e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_2 PF07716.15 CEP19128.1 - 0.00071 19.6 10.2 0.00071 19.6 10.2 2.4 1 1 0 2 2 2 2 Basic region leucine zipper CCDC85 PF10226.9 CEP19128.1 - 0.0056 16.4 0.9 0.0056 16.4 0.9 1.7 2 0 0 2 2 2 1 CCDC85 family PRKG1_interact PF15898.5 CEP19128.1 - 0.3 12.0 9.6 0.2 12.6 6.2 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TAF8_C PF10406.9 CEP19129.1 - 2.1e-16 60.2 1.9 2.1e-16 60.2 1.9 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CEP19129.1 - 5.3e-13 48.8 0.0 8.6e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 CEP19129.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Histone-fold protein SAGA-Tad1 PF12767.7 CEP19129.1 - 0.013 15.2 3.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.9 CEP19129.1 - 0.039 13.6 7.3 0.058 13.0 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LUC7 PF03194.15 CEP19129.1 - 0.097 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 LUC7 N_terminus NPR1_interact PF15699.5 CEP19129.1 - 0.81 10.3 4.6 0.29 11.8 0.7 2.1 1 1 1 2 2 2 0 NPR1 interacting DDE_Tnp_4 PF13359.6 CEP19130.1 - 0.0049 16.6 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 CEP19132.1 - 2.2e-21 76.2 0.0 3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 CEP19132.1 - 0.00056 19.6 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Myb_DNA-bind_5 PF13873.6 CEP19133.1 - 1.5e-05 25.0 0.7 0.00048 20.1 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP19133.1 - 0.00033 20.8 0.1 0.00058 20.0 0.1 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CEP19133.1 - 0.028 14.7 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CEP19133.1 - 0.037 14.4 0.0 0.057 13.8 0.0 1.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.6 CEP19134.1 - 0.62 10.5 4.3 0.34 11.3 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GOLD_2 PF13897.6 CEP19134.1 - 6.2 7.3 7.6 0.5 10.9 0.8 2.2 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking CDK2AP PF09806.9 CEP19135.1 - 0.026 14.6 0.6 0.03 14.4 0.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1192 PF06698.11 CEP19135.1 - 0.035 14.2 0.4 0.072 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PROL5-SMR PF15621.6 CEP19135.1 - 0.042 14.4 1.7 0.25 11.9 0.3 2.2 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family TMF_DNA_bd PF12329.8 CEP19135.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CEP19135.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Myb_DNA-bind_5 PF13873.6 CEP19136.1 - 5.6e-06 26.3 0.6 0.00046 20.2 0.3 2.1 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CEP19136.1 - 0.001 19.2 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain muHD PF10291.9 CEP19138.1 - 3e-26 92.4 0.7 5e-26 91.7 0.7 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CEP19138.1 - 9.7e-12 45.0 0.0 9.7e-12 45.0 0.0 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1735 PF08522.10 CEP19138.1 - 0.057 14.0 0.0 0.19 12.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Occludin_ELL PF07303.13 CEP19138.1 - 1.4 9.7 9.0 0.31 11.8 4.8 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF148 PF02520.17 CEP19138.1 - 3.1 7.9 11.3 3.2 7.9 3.3 2.9 1 1 0 2 2 2 0 Domain of unknown function DUF148 CBM_19 PF03427.13 CEP19140.1 - 8e-21 73.8 55.5 2.3e-06 27.5 7.5 4.6 4 0 0 4 4 4 4 Carbohydrate binding domain (family 19) I-EGF_1 PF18372.1 CEP19140.1 - 1.6 8.9 15.6 11 6.2 0.3 4.9 4 0 0 4 4 4 0 Integrin beta epidermal growth factor like domain 1 EPL1 PF10513.9 CEP19141.1 - 1.3e-20 74.3 3.1 1.3e-20 74.3 3.1 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like DUF778 PF05608.12 CEP19141.1 - 1.6 9.0 5.7 12 6.2 2.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF778) Rtt106 PF08512.12 CEP19142.1 - 8.6e-30 103.0 0.1 3.2e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 CEP19142.1 - 1.7e-26 92.5 0.1 8.4e-23 80.6 0.0 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 CEP19142.1 - 2.3e-23 81.9 0.0 7.1e-23 80.3 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) MRF_C1 PF13887.6 CEP19142.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 RhoGEF PF00621.20 CEP19143.1 - 1.8e-26 93.5 0.2 3.1e-26 92.7 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CEP19143.1 - 1.6e-05 25.4 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PH domain CCDC158 PF15921.5 CEP19143.1 - 3.1 5.5 5.0 4 5.1 5.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 ADK PF00406.22 CEP19145.1 - 2.1e-49 167.5 0.1 2.6e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CEP19145.1 - 9.2e-39 133.0 0.2 1.3e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CEP19145.1 - 3.6e-11 43.7 0.1 5.2e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CEP19145.1 - 2.1e-08 34.1 2.1 0.00035 20.3 0.5 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CEP19145.1 - 0.0001 22.5 0.1 0.0011 19.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CEP19145.1 - 0.00014 21.2 0.1 0.00025 20.4 0.1 1.5 1 1 0 1 1 1 1 Zeta toxin UvrD_C PF13361.6 CEP19145.1 - 0.011 15.1 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain dNK PF01712.19 CEP19145.1 - 0.053 13.4 2.0 0.1 12.5 0.7 2.0 1 1 1 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 CEP19145.1 - 0.077 13.5 0.3 0.34 11.4 0.3 2.0 1 1 0 1 1 1 0 ABC transporter Acyl_transf_2 PF02273.15 CEP19145.1 - 0.12 11.5 0.1 4.7 6.4 0.0 2.0 1 1 0 2 2 2 0 Acyl transferase Lip_prot_lig_C PF10437.9 CEP19147.1 - 3.7e-07 30.0 0.8 7.1e-06 25.9 0.0 3.0 4 0 0 4 4 4 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 CEP19147.1 - 4.3e-06 26.7 0.0 2.4e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family CbiC PF02570.15 CEP19147.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF1754 PF08555.10 CEP19148.1 - 1.4e-05 25.8 28.9 0.00012 22.8 23.8 2.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) RabGAP-TBC PF00566.18 CEP19148.1 - 0.014 15.0 3.8 0.016 14.8 3.8 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF4618 PF15397.6 CEP19148.1 - 0.018 14.5 12.4 0.021 14.3 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2524 PF10732.9 CEP19148.1 - 0.063 13.6 8.3 0.098 13.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) SopE_GEF PF07487.13 CEP19148.1 - 0.14 12.2 6.5 0.43 10.7 6.5 1.8 1 1 0 1 1 1 0 SopE GEF domain DUF4191 PF13829.6 CEP19148.1 - 0.17 11.2 3.3 0.23 10.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) OmpH PF03938.14 CEP19148.1 - 0.27 11.6 14.8 0.36 11.2 14.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atrophin-1 PF03154.15 CEP19148.1 - 0.27 9.5 12.5 0.28 9.4 12.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family Exonuc_VII_L PF02601.15 CEP19148.1 - 0.45 10.0 7.6 0.49 9.9 7.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S46 PF10459.9 CEP19148.1 - 0.48 9.0 7.2 0.52 8.9 7.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Allexi_40kDa PF05549.11 CEP19148.1 - 0.55 9.7 3.2 0.62 9.5 3.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ribosomal_L37 PF08561.10 CEP19148.1 - 1.3 9.6 12.1 1.5 9.3 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 V_ATPase_I PF01496.19 CEP19148.1 - 1.4 6.7 9.7 1.6 6.5 9.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ZYG-11_interact PF05884.12 CEP19148.1 - 1.4 8.2 3.0 1.7 8.0 3.0 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 LicD PF04991.13 CEP19148.1 - 2.1 8.4 8.5 2.3 8.3 8.5 1.0 1 0 0 1 1 1 0 LicD family YlqD PF11068.8 CEP19148.1 - 2.1 8.7 14.6 2.6 8.4 14.6 1.1 1 0 0 1 1 1 0 YlqD protein 5_nucleotid PF05761.14 CEP19148.1 - 6.1 5.6 10.1 7.5 5.3 10.1 1.0 1 0 0 1 1 1 0 5' nucleotidase family LMBR1 PF04791.16 CEP19148.1 - 6.2 5.6 6.6 6.6 5.5 6.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 CEP19148.1 - 6.8 5.6 7.0 7.3 5.5 7.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein TMPIT PF07851.13 CEP19148.1 - 9.2 5.4 9.9 12 5.0 9.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein CAF1A PF12253.8 CEP19149.1 - 1.4e-25 89.3 2.2 1.4e-25 89.3 2.2 3.3 2 1 1 3 3 1 1 Chromatin assembly factor 1 subunit A eIF3_subunit PF08597.10 CEP19149.1 - 0.0059 16.6 26.3 0.0059 16.6 26.3 2.6 3 0 0 3 3 2 1 Translation initiation factor eIF3 subunit Borrelia_P83 PF05262.11 CEP19149.1 - 0.09 11.2 24.5 0.15 10.5 24.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.8 CEP19149.1 - 0.13 11.9 47.9 0.26 11.0 47.9 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.11 CEP19149.1 - 0.25 11.4 26.1 0.59 10.1 26.1 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GAGA_bind PF06217.12 CEP19149.1 - 0.41 10.9 17.9 0.8 9.9 17.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.8 CEP19149.1 - 1.8 7.4 30.7 3.1 6.6 30.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.10 CEP19149.1 - 3 8.1 31.7 10 6.4 29.9 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 CEP19149.1 - 3.8 7.9 13.6 12 6.3 13.6 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CEP19149.1 - 4 7.2 27.2 10 5.9 27.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.18 CEP19149.1 - 4 5.7 4.2 6 5.2 4.2 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3402 PF11882.8 CEP19150.1 - 1.5e-86 291.3 22.2 8.3e-52 176.8 0.5 3.9 2 1 2 4 4 4 3 Domain of unknown function (DUF3402) N1221 PF07923.13 CEP19150.1 - 5.8e-35 120.9 1.7 5.8e-35 120.9 1.7 2.3 2 1 0 2 2 2 1 N1221-like protein Terpene_synth_C PF03936.16 CEP19150.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain AAA_23 PF13476.6 CEP19150.1 - 1.5 9.2 10.0 5.7 7.4 0.5 2.6 2 0 0 2 2 2 0 AAA domain Tub_N PF16322.5 CEP19150.1 - 2.1 8.7 5.0 0.63 10.4 1.9 1.7 2 0 0 2 2 2 0 Tubby N-terminal RXT2_N PF08595.11 CEP19150.1 - 3 7.9 13.8 0.31 11.0 4.0 3.6 4 0 0 4 4 4 0 RXT2-like, N-terminal BUD22 PF09073.10 CEP19150.1 - 5.2 6.3 7.5 8.2 5.6 7.5 1.2 1 0 0 1 1 1 0 BUD22 Abhydrolase_1 PF00561.20 CEP19151.1 - 1e-20 74.5 0.1 1.7e-20 73.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CEP19151.1 - 6.1e-17 60.9 0.2 2.1e-16 59.2 0.2 1.9 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CEP19151.1 - 1e-05 24.9 0.0 0.00094 18.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CEP19151.1 - 0.00062 20.4 0.2 0.00082 20.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.32 CEP19152.1 - 2.2e-40 135.9 19.7 5e-06 27.1 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19152.1 - 4.1e-20 71.9 3.6 0.005 17.1 0.0 6.0 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP19152.1 - 1.8e-07 31.2 0.7 0.0071 16.2 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CEP19152.1 - 3.3e-07 29.6 2.6 0.076 12.0 0.3 4.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CEP19152.1 - 5.4e-06 26.0 0.1 0.001 18.5 0.3 2.8 1 1 2 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 CEP19152.1 - 1.8e-05 23.5 0.1 0.091 11.3 0.0 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain BBS2_Mid PF14783.6 CEP19152.1 - 0.00031 20.8 0.1 1.5 8.9 0.0 4.3 2 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.14 CEP19152.1 - 0.0085 15.2 0.1 4.7 6.2 0.0 2.9 1 1 2 3 3 3 1 Coatomer WD associated region PQQ_3 PF13570.6 CEP19152.1 - 0.0091 16.5 0.9 1.9 9.1 0.1 3.2 2 1 1 3 3 3 1 PQQ-like domain PQQ PF01011.21 CEP19152.1 - 0.015 15.2 0.9 13 5.9 0.1 4.6 5 0 0 5 5 5 0 PQQ enzyme repeat VID27 PF08553.10 CEP19152.1 - 0.016 14.3 0.0 0.038 13.1 0.0 1.6 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain VCBS PF13517.6 CEP19152.1 - 0.55 10.9 4.0 4.1 8.1 1.2 2.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Aminotran_1_2 PF00155.21 CEP19153.1 - 5.7e-43 147.5 0.0 8.6e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_zinc_N PF00107.26 CEP19153.1 - 5.8e-05 23.1 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP19153.1 - 0.00059 19.7 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cys_Met_Meta_PP PF01053.20 CEP19153.1 - 0.0038 15.8 0.0 0.006 15.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NodS PF05401.11 CEP19153.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Beta_elim_lyase PF01212.21 CEP19153.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase ADH_N PF08240.12 CEP19154.1 - 6.7e-26 90.3 8.1 1.3e-25 89.4 8.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CEP19154.1 - 2e-15 56.9 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CEP19154.1 - 7.9e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CEP19154.1 - 0.00039 19.8 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CEP19154.1 - 0.0021 19.1 0.0 0.0033 18.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 CEP19154.1 - 0.0057 16.8 0.0 0.0098 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_31 PF13847.6 CEP19154.1 - 0.0099 15.7 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 CEP19154.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 CEP19154.1 - 0.92 9.6 5.5 2.7 8.1 5.5 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sin3a_C PF16879.5 CEP19155.1 - 1.2e-58 199.1 9.4 1.2e-58 199.1 9.4 3.5 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 CEP19155.1 - 1.2e-41 140.6 13.8 9e-18 64.2 0.0 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CEP19155.1 - 2.4e-41 139.7 2.9 4.2e-41 139.0 0.7 2.5 2 0 0 2 2 2 1 Sin3 family co-repressor RSB_motif PF16294.5 CEP19155.1 - 0.068 13.4 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif Pyridox_oxase_2 PF12766.7 CEP19156.1 - 0.00048 20.7 0.0 0.00078 20.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Methyltransf_25 PF13649.6 CEP19157.1 - 7.2e-09 36.2 0.0 1.4e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP19157.1 - 4e-08 32.9 0.1 5.2e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CEP19157.1 - 7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP19157.1 - 7.6e-05 22.5 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CEP19157.1 - 0.00043 21.3 0.0 0.00065 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP19157.1 - 0.018 15.8 0.2 0.037 14.7 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 CEP19157.1 - 0.17 11.4 0.1 0.48 9.9 0.0 1.7 2 1 0 2 2 2 0 Putative methyltransferase cwf21 PF08312.12 CEP19157.1 - 0.94 9.7 2.9 1.7 8.8 2.9 1.4 1 0 0 1 1 1 0 cwf21 domain SH2_2 PF14633.6 CEP19158.1 - 1.3e-69 233.9 0.0 1.3e-69 233.9 0.0 2.1 2 0 0 2 2 1 1 SH2 domain YqgF PF14639.6 CEP19158.1 - 4.2e-32 111.0 0.1 1.2e-31 109.5 0.1 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 CEP19158.1 - 2.1e-30 105.5 0.4 6.4e-30 103.9 0.4 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 CEP19158.1 - 4.1e-27 94.6 0.0 9.2e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 CEP19158.1 - 2.2e-18 66.6 22.0 2.2e-18 66.6 22.0 6.4 3 1 3 6 6 3 1 Acidic N-terminal SPT6 S1 PF00575.23 CEP19158.1 - 2.1e-07 31.2 0.1 6.1e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 CEP19158.1 - 2.7e-06 27.4 0.0 8.8e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 CEP19158.1 - 1.3e-05 25.7 0.1 2.7e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 CEP19158.1 - 0.00011 22.3 0.0 0.00033 20.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 CEP19158.1 - 0.0003 21.6 0.8 0.0022 18.8 0.3 3.0 2 1 0 2 2 2 1 HHH domain PT-HINT PF07591.11 CEP19158.1 - 0.0012 19.1 0.1 0.058 13.6 0.0 2.9 3 0 0 3 3 3 1 Pretoxin HINT domain Tex_N PF09371.10 CEP19158.1 - 0.026 14.2 1.2 0.27 10.9 0.0 3.2 4 0 0 4 4 4 0 Tex-like protein N-terminal domain Malate_synthase PF01274.22 CEP19163.1 - 1.1e-224 746.5 0.0 1.3e-224 746.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CEP19163.1 - 0.0079 15.3 0.0 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peptidase_M48_N PF16491.5 CEP19164.1 - 8.4e-66 221.3 9.8 8.4e-66 221.3 9.8 2.3 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CEP19164.1 - 2e-48 164.8 0.3 4.8e-48 163.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 CEP19164.1 - 3.8e-05 23.0 0.6 0.00041 19.6 0.8 2.3 3 0 0 3 3 3 1 BlaR1 peptidase M56 SprT-like PF10263.9 CEP19164.1 - 0.0055 16.5 0.2 0.0099 15.7 0.2 1.4 1 0 0 1 1 1 1 SprT-like family WD40 PF00400.32 CEP19165.1 - 3.8e-10 40.2 9.7 0.0012 19.6 0.2 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Ins_P5_2-kin PF06090.12 CEP19166.1 - 2.7e-70 237.4 0.7 3.1e-70 237.3 0.7 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Rota_NS53 PF00981.17 CEP19166.1 - 0.02 13.8 0.2 0.036 13.0 0.2 1.4 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Zn_ribbon_SprT PF17283.2 CEP19166.1 - 0.054 13.4 0.2 0.097 12.6 0.2 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Syntaxin-6_N PF09177.11 CEP19166.1 - 0.075 13.6 0.8 14 6.3 0.0 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal MIP-T3_C PF17749.1 CEP19166.1 - 0.13 12.2 0.2 0.24 11.4 0.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Ecl1 PF12855.7 CEP19167.1 - 4.8e-10 40.9 9.1 7.2e-10 40.3 9.1 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-C2H2_jaz PF12171.8 CEP19167.1 - 3.8 7.9 7.0 1 9.8 3.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NAC PF01849.18 CEP19168.1 - 7.2e-24 83.5 0.1 2.9e-23 81.6 0.0 2.1 2 0 0 2 2 2 1 NAC domain Peptidase_C48 PF02902.19 CEP19168.1 - 5.2e-11 42.8 1.7 3.1e-10 40.3 0.1 2.6 1 1 1 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SR-25 PF10500.9 CEP19168.1 - 0.0056 16.3 7.0 0.011 15.4 7.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pyrophosphatase PF00719.19 CEP19170.1 - 4.8e-59 198.7 0.4 6.5e-59 198.3 0.4 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase G-alpha PF00503.20 CEP19171.1 - 2.5e-109 365.7 3.3 3.1e-109 365.4 3.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CEP19171.1 - 6.6e-15 55.0 1.0 5e-10 39.1 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CEP19171.1 - 0.00014 21.3 0.3 0.41 10.0 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CEP19171.1 - 0.00038 20.7 0.4 0.37 11.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CEP19171.1 - 0.0064 16.2 0.6 0.0095 15.7 0.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEP19171.1 - 0.049 13.4 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CEP19171.1 - 0.083 12.4 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MASE4 PF17158.4 CEP19172.1 - 0.0063 15.8 0.7 0.0083 15.4 0.7 1.0 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain DUF448 PF04296.13 CEP19172.1 - 0.14 12.0 0.1 9.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF448) Pro_isomerase PF00160.21 CEP19173.1 - 1.1e-48 165.6 0.4 1.3e-48 165.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ThiF PF00899.21 CEP19174.1 - 2e-109 364.6 0.0 6.3e-73 245.1 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CEP19174.1 - 1.6e-92 310.0 0.1 3.1e-92 309.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CEP19174.1 - 1.1e-36 125.4 0.2 2.5e-36 124.2 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CEP19174.1 - 2.1e-33 114.3 0.2 5.2e-33 113.1 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CEP19174.1 - 6.7e-27 93.5 0.8 1.8e-26 92.1 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Strep_SA_rep PF06696.11 CEP19174.1 - 0.05 13.6 0.3 0.16 12.0 0.3 1.9 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Sacchrp_dh_NADP PF03435.18 CEP19174.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain E2_bind PF08825.10 CEP19174.1 - 0.16 12.2 0.0 0.51 10.5 0.0 1.9 1 0 0 1 1 1 0 E2 binding domain SMP PF04927.12 CEP19175.1 - 0.011 16.2 1.5 0.013 16.0 0.7 1.6 1 1 0 1 1 1 0 Seed maturation protein Ifi-6-16 PF06140.13 CEP19175.1 - 0.037 14.0 0.3 0.043 13.7 0.3 1.1 1 0 0 1 1 1 0 Interferon-induced 6-16 family TrpP PF17099.5 CEP19176.1 - 0.058 13.2 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan transporter TrpP Pkinase PF00069.25 CEP19177.1 - 1e-66 225.0 0.0 1.9e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19177.1 - 2.6e-53 181.0 0.0 4e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19177.1 - 3.4e-05 23.3 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like zf-RING_2 PF13639.6 CEP19177.1 - 0.00061 20.1 10.0 0.0048 17.2 10.1 2.3 2 0 0 2 2 2 1 Ring finger domain RIO1 PF01163.22 CEP19177.1 - 0.00067 19.3 0.5 0.002 17.7 0.5 1.9 1 0 0 1 1 1 1 RIO1 family zf-C3HC4_2 PF13923.6 CEP19177.1 - 0.042 13.7 13.6 0.38 10.6 11.4 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YrbL-PhoP_reg PF10707.9 CEP19177.1 - 0.67 9.4 3.4 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PHD PF00628.29 CEP19177.1 - 1.7 8.6 10.1 4.3 7.3 10.1 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CEP19177.1 - 2 8.8 11.1 6 7.3 11.1 1.9 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.6 CEP19177.1 - 9.3 6.3 11.3 30 4.7 11.3 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Hemerythrin PF01814.23 CEP19179.1 - 1.3e-11 45.2 1.3 1.9e-11 44.7 1.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4841 PF16129.5 CEP19179.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) DNA_ligase_A_M PF01068.21 CEP19180.1 - 5.7e-42 143.7 0.7 1.4e-41 142.4 0.7 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CEP19180.1 - 3.5e-36 125.1 0.9 3.5e-36 125.1 0.9 1.8 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 CEP19180.1 - 9.8e-15 54.7 0.0 6.1e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 CEP19180.1 - 4.6e-14 53.0 0.2 1.2e-13 51.7 0.2 1.7 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 CEP19180.1 - 5.4e-08 33.4 0.0 2.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 CEP19180.1 - 5.7e-06 26.3 1.0 0.094 12.5 0.1 2.9 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain BRCT PF00533.26 CEP19180.1 - 9.3e-05 22.7 0.0 0.066 13.6 0.0 3.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PP1 PF07430.11 CEP19180.1 - 0.063 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain QCR10 PF09796.9 CEP19180.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MMS19_N PF14500.6 CEP19180.1 - 0.3 10.6 2.9 69 2.9 0.0 4.1 4 1 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DSPc PF00782.20 CEP19181.1 - 9.1e-27 93.5 2.0 4.5e-19 68.6 0.7 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP19181.1 - 7e-06 25.8 0.1 1.3e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CEP19181.1 - 0.016 15.5 0.6 0.058 13.7 0.1 2.2 1 1 0 2 2 2 0 Rit1 DUSP-like domain Y_phosphatase2 PF03162.13 CEP19181.1 - 0.028 14.0 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3644 PF12358.8 CEP19181.1 - 0.062 13.8 0.1 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) HABP4_PAI-RBP1 PF04774.15 CEP19182.1 - 9.4e-05 23.2 6.6 9.4e-05 23.2 6.6 3.6 2 2 0 2 2 2 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 CEP19182.1 - 0.17 12.8 0.0 0.17 12.8 0.0 3.7 4 1 0 4 4 4 0 Stm1 Methyltransf_31 PF13847.6 CEP19183.1 - 1.2e-13 51.1 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CEP19183.1 - 1.6e-10 40.8 0.1 3.1e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CEP19183.1 - 4.2e-09 37.0 0.0 9.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CEP19183.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 CEP19183.1 - 2e-06 28.4 0.0 5.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PseudoU_synth_2 PF00849.22 CEP19183.1 - 3.1e-06 27.4 0.0 6.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase PrmA PF06325.13 CEP19183.1 - 3.6e-06 26.6 0.4 1e-05 25.1 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 CEP19183.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_11 PF08241.12 CEP19183.1 - 0.0047 17.6 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CEP19183.1 - 0.0055 16.6 0.1 0.018 15.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CEP19183.1 - 0.0064 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19183.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CEP19183.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 E1_FCCH PF16190.5 CEP19183.1 - 0.083 13.1 0.0 24 5.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain Whi5 PF08528.11 CEP19184.1 - 0.0004 19.9 0.1 0.0008 19.0 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Ilar_coat PF01787.16 CEP19185.1 - 0.098 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein LapA_dom PF06305.11 CEP19185.1 - 5.3 6.9 6.3 9.3 6.1 0.1 3.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 CEP19185.1 - 8.4 6.9 9.3 27 5.3 0.2 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF202) NTF2 PF02136.20 CEP19186.1 - 3.6e-28 98.5 0.1 4.7e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Thioredoxin PF00085.20 CEP19187.1 - 6.1e-62 206.0 0.0 1.1e-30 105.7 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin ERp29 PF07749.12 CEP19187.1 - 2.8e-22 79.4 0.6 6.6e-22 78.2 0.6 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CEP19187.1 - 3.4e-15 56.2 0.0 2e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CEP19187.1 - 2.1e-11 44.2 0.0 0.00014 22.2 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CEP19187.1 - 2.9e-09 37.0 0.0 0.00012 22.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CEP19187.1 - 1.8e-07 31.1 0.1 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CEP19187.1 - 1.1e-05 25.7 0.0 0.34 11.3 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like HyaE PF07449.11 CEP19187.1 - 0.00082 19.3 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CEP19187.1 - 0.017 15.0 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF2452 PF10504.9 CEP19187.1 - 0.084 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Pyridoxal_deC PF00282.19 CEP19188.1 - 4.9e-84 282.2 0.0 8.3e-84 281.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RasGEF PF00617.19 CEP19188.1 - 7.7e-59 198.8 0.4 1.9e-58 197.6 0.4 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CEP19188.1 - 1.4e-29 102.4 1.1 8.4e-29 99.9 0.4 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 CEP19188.1 - 5.7e-14 51.5 0.4 1.5e-13 50.1 0.4 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CEP19188.1 - 8.9e-11 41.3 0.0 2.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CEP19188.1 - 2.8e-10 39.9 0.1 6.1e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CEP19188.1 - 3.5e-07 30.2 2.4 0.0027 17.8 0.1 3.4 3 0 0 3 3 3 2 WW domain Aminotran_5 PF00266.19 CEP19188.1 - 1.7e-05 24.0 0.0 8.5e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEP19188.1 - 0.00016 21.0 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GIT1_C PF12205.8 CEP19188.1 - 0.077 13.1 1.8 0.71 10.0 0.2 3.1 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term HAD_2 PF13419.6 CEP19189.1 - 1.4e-08 35.0 0.0 2.1e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP19189.1 - 2.7e-07 31.1 0.0 6.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP19189.1 - 0.1 12.7 0.1 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 HAD-hyrolase-like zf-H2C2_2 PF13465.6 CEP19191.1 - 2.8e-08 33.8 8.3 1.1e-06 28.8 3.0 3.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CEP19191.1 - 4.2e-05 23.8 1.1 4.2e-05 23.8 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF629 PF04780.12 CEP19191.1 - 0.028 12.9 0.0 0.028 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 CEP19191.1 - 0.03 15.2 0.6 0.03 15.2 0.6 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP19191.1 - 0.15 12.7 0.2 0.15 12.7 0.2 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain CLP1_P PF16575.5 CEP19192.1 - 1.7e-39 135.5 0.0 4.1e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop KH_dom-like PF14714.6 CEP19192.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal MAP7 PF05672.11 CEP19192.1 - 1.8 8.2 7.9 3.1 7.5 7.9 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DDE_3 PF13358.6 CEP19195.1 - 0.038 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease LMBR1 PF04791.16 CEP19197.1 - 2.4e-114 383.1 27.8 2.4e-114 383.1 27.8 1.3 2 0 0 2 2 2 1 LMBR1-like membrane protein ADH_zinc_N_2 PF13602.6 CEP19198.1 - 4.7e-14 53.6 0.0 1.1e-13 52.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CEP19198.1 - 2e-13 50.5 0.0 4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP19198.1 - 5.6e-11 42.3 1.3 4.4e-10 39.4 0.1 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 CEP19198.1 - 0.002 17.9 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.24 CEP19198.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CEP19198.1 - 0.081 12.4 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 CEP19198.1 - 0.086 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2781 PF10914.8 CEP19199.1 - 6.1e-43 146.8 13.5 7e-43 146.6 13.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) His_Phos_1 PF00300.22 CEP19200.1 - 3.7e-38 131.2 0.0 4.6e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GCV_T PF01571.21 CEP19201.1 - 2.9e-88 295.6 0.1 4.3e-88 295.0 0.1 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain RabGAP-TBC PF00566.18 CEP19201.1 - 3.1e-56 190.4 0.3 3.1e-56 190.4 0.3 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain GCV_T_C PF08669.11 CEP19201.1 - 1.5e-20 72.8 0.1 3.6e-20 71.7 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CEP19201.1 - 0.00065 19.9 0.1 0.62 10.2 0.0 2.5 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family Cep57_CLD_2 PF14197.6 CEP19201.1 - 0.0035 17.4 10.2 0.0035 17.4 10.2 2.4 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 GAS PF13851.6 CEP19201.1 - 3.8 6.8 24.3 15 4.9 24.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 CEP19202.1 - 7.6e-41 140.2 28.9 7.6e-41 140.2 28.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP19202.1 - 8.7e-05 21.6 3.1 8.7e-05 21.6 3.1 3.5 2 1 0 3 3 3 2 Sugar (and other) transporter DUF5058 PF16481.5 CEP19202.1 - 0.016 14.9 0.2 0.016 14.9 0.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5058) MFS_3 PF05977.13 CEP19202.1 - 0.8 8.0 10.4 0.015 13.7 3.0 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector HsbA PF12296.8 CEP19203.1 - 9.3e-18 64.8 1.5 9.3e-18 64.8 1.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A SesA PF17107.5 CEP19203.1 - 0.011 15.9 0.6 0.023 14.9 0.1 1.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sdh5 PF03937.16 CEP19204.1 - 8.8e-29 99.3 0.4 1.2e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF5137 PF17220.3 CEP19204.1 - 0.12 13.3 2.0 0.24 12.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF5137) PRA-CH PF01502.18 CEP19204.1 - 0.17 11.7 0.2 2.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase Pkinase PF00069.25 CEP19205.1 - 1.5e-50 172.0 0.0 1.9e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19205.1 - 5.7e-23 81.5 0.0 7.3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19205.1 - 0.00084 18.7 0.2 0.2 11.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Arf PF00025.21 CEP19206.1 - 8.8e-77 256.5 0.1 1e-76 256.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP19206.1 - 9.5e-16 58.1 0.1 1.3e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CEP19206.1 - 4.4e-14 52.4 0.0 5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CEP19206.1 - 2.6e-12 46.5 0.0 3.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CEP19206.1 - 2.6e-11 43.3 2.3 4.7e-07 29.3 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CEP19206.1 - 9.5e-11 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP19206.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEP19206.1 - 0.0039 16.5 0.1 0.0059 15.9 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 CEP19206.1 - 0.16 12.5 0.2 0.38 11.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain P5CR_dimer PF14748.6 CEP19207.1 - 2.2e-35 121.0 2.0 2.2e-35 121.0 2.0 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CEP19207.1 - 3.6e-16 59.5 0.4 8.6e-16 58.3 0.1 1.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CEP19207.1 - 0.00055 19.9 1.0 0.0014 18.6 0.5 2.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.15 CEP19207.1 - 0.0044 16.0 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_2 PF03446.15 CEP19207.1 - 0.0046 17.1 0.0 0.0094 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 CEP19207.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.16 CEP19207.1 - 0.077 12.6 1.2 0.46 10.1 1.2 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 CEP19208.1 - 0.0019 18.3 16.0 0.0032 17.5 16.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TP1 PF02079.16 CEP19208.1 - 8.3 6.4 11.8 1.2 9.0 3.4 2.3 2 0 0 2 2 2 0 Nuclear transition protein 1 DUF3543 PF12063.8 CEP19209.1 - 4.9e-49 167.0 8.3 2.1e-46 158.3 5.8 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF3543) Pkinase PF00069.25 CEP19209.1 - 7.5e-44 150.1 0.0 1.3e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19209.1 - 4.4e-24 85.2 0.0 6.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP19209.1 - 0.0018 17.1 0.2 0.067 12.0 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CEP19209.1 - 0.0088 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Saw1 PF11561.8 CEP19209.1 - 0.058 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 RRM_1 PF00076.22 CEP19210.1 - 6.7e-20 70.7 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CEP19210.1 - 2.4e-07 30.8 0.1 3.4e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CEP19210.1 - 0.00054 19.5 0.1 0.0015 18.1 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mannosyl_trans3 PF11051.8 CEP19211.1 - 2.6e-37 128.7 0.1 2.4e-26 92.7 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Mating_N PF12731.7 CEP19211.1 - 0.19 11.8 0.1 0.42 10.7 0.1 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Cmc1 PF08583.10 CEP19212.1 - 4.7e-16 58.6 4.7 5.7e-16 58.3 4.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CEP19212.1 - 0.13 12.5 3.2 0.22 11.8 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.13 CEP19212.1 - 0.14 12.5 3.2 6.1 7.3 0.3 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zf-RVT PF13966.6 CEP19213.1 - 0.00016 22.3 2.4 0.0002 22.0 2.4 1.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RecR PF02132.15 CEP19213.1 - 0.089 12.4 0.6 0.14 11.8 0.6 1.3 1 0 0 1 1 1 0 RecR protein DUF5633 PF18656.1 CEP19214.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5633) CytochromB561_N PF09786.9 CEP19215.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome B561, N terminal Tim54 PF11711.8 CEP19215.1 - 0.045 12.5 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LtrA PF06772.11 CEP19216.1 - 1.2e-34 120.1 19.1 1.2e-34 120.1 19.1 2.5 2 1 1 3 3 3 1 Bacterial low temperature requirement A protein (LtrA) NT-C2 PF10358.9 CEP19216.1 - 0.12 12.1 0.3 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 CEP19217.1 - 6.8e-69 227.9 2.7 1.1e-24 86.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 CEP19217.1 - 0.027 14.4 1.2 0.052 13.5 1.2 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Fuseless PF15993.5 CEP19217.1 - 0.11 11.7 0.1 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Fuseless Fe-S_biosyn PF01521.20 CEP19218.1 - 2e-17 63.4 0.1 2.8e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Enolase_N PF03952.16 CEP19218.1 - 0.046 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Enolase, N-terminal domain zf-CCHC PF00098.23 CEP19219.1 - 8.8e-05 22.4 1.3 0.00014 21.8 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CEP19219.1 - 0.12 12.3 1.3 0.2 11.5 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEP19219.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.5 2 0 0 2 2 2 0 Zinc knuckle Shadoo PF14999.6 CEP19219.1 - 0.95 9.6 10.0 1.7 8.7 10.0 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective adh_short PF00106.25 CEP19220.1 - 9.4e-82 273.2 12.1 4.8e-41 140.4 1.5 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CEP19220.1 - 1.7e-65 220.9 11.3 7.3e-33 114.1 0.9 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CEP19220.1 - 1.5e-33 115.0 0.0 3.6e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CEP19220.1 - 3e-30 105.5 9.9 2.9e-17 63.2 2.3 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 CEP19220.1 - 2e-05 24.8 0.0 0.00022 21.3 0.0 2.7 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 CEP19220.1 - 5.4e-05 22.6 2.3 0.22 10.8 0.4 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CEP19220.1 - 1.1 9.1 7.5 7.6 6.4 0.9 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 CEP19220.1 - 1.8 8.4 6.5 14 5.5 0.4 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase HAD_2 PF13419.6 CEP19221.1 - 2.1e-21 76.8 0.0 2.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP19221.1 - 2.4e-16 60.6 1.5 7.2e-14 52.6 0.5 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP19221.1 - 5.4e-08 32.8 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CEP19221.1 - 0.076 13.4 0.1 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DNA_meth_N PF18284.1 CEP19221.1 - 0.16 11.9 0.3 25 4.8 0.1 2.5 2 0 0 2 2 2 0 DNA methylase N-terminal domain Spc42p PF11544.8 CEP19222.1 - 0.02 14.9 0.3 0.043 13.8 0.2 1.6 1 1 0 1 1 1 0 Spindle pole body component Spc42p zf-C2H2 PF00096.26 CEP19223.1 - 6.6e-15 54.6 20.2 6.9e-07 29.4 3.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP19223.1 - 1.4e-10 41.1 16.6 0.0019 18.9 1.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP19223.1 - 4.6e-10 39.5 15.2 3e-06 27.4 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CEP19223.1 - 6.5e-07 29.2 9.3 0.011 15.7 0.1 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP19223.1 - 2.5e-05 24.5 2.4 0.81 10.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CEP19223.1 - 0.00077 19.9 3.5 0.16 12.4 0.7 2.7 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 CEP19223.1 - 0.046 13.9 1.4 0.046 13.9 1.4 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 CEP19223.1 - 0.057 13.2 10.8 0.98 9.2 0.3 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type DZR PF12773.7 CEP19223.1 - 0.086 12.9 3.6 0.35 10.9 3.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-met PF12874.7 CEP19223.1 - 0.13 12.7 4.9 13 6.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 CEP19223.1 - 0.16 12.0 5.4 5.7 7.0 0.4 2.9 2 1 0 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 CEP19223.1 - 0.62 10.2 7.3 0.48 10.6 2.6 2.9 1 1 1 3 3 3 0 Zinc ribbon domain PknG_rubred PF16919.5 CEP19223.1 - 0.73 10.0 4.6 11 6.2 0.8 2.4 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain Zn_ribbon_SprT PF17283.2 CEP19223.1 - 1.2 9.1 7.1 1.8 8.5 4.5 2.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf_ZIC PF18366.1 CEP19223.1 - 2 8.6 5.2 27 5.0 0.2 3.2 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 CEP19223.1 - 4.5 7.7 11.0 69 3.9 9.9 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 CEP19223.1 - 9.8 6.2 8.9 30 4.6 0.0 3.7 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger QWRF PF04484.12 CEP19224.1 - 0.019 14.7 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 QWRF family FTZ PF03867.14 CEP19224.1 - 0.07 12.7 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Couple_hipA PF13657.6 CEP19224.1 - 0.16 12.6 0.1 0.49 11.1 0.0 1.9 2 1 0 2 2 2 0 HipA N-terminal domain SET PF00856.28 CEP19225.1 - 2.3e-08 34.6 0.0 4.5e-07 30.4 0.0 2.0 1 1 1 2 2 2 1 SET domain SH3_1 PF00018.28 CEP19226.1 - 1.5e-15 56.5 0.1 2.3e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP19226.1 - 2.6e-14 52.8 0.0 4.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CEP19226.1 - 3.5e-14 52.2 0.0 7.1e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Isochorismatase PF00857.20 CEP19228.1 - 1.2e-20 74.4 0.0 2.5e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family HMG_box PF00505.19 CEP19233.1 - 1.8e-15 57.1 1.7 1.8e-15 57.1 1.7 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 CEP19233.1 - 1.5e-12 47.8 0.6 2.7e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 CEP19233.1 - 4.3e-11 43.2 1.8 4.3e-11 43.2 1.8 2.4 1 1 1 2 2 2 1 HMG-box domain SAM_2 PF07647.17 CEP19233.1 - 3e-08 33.7 0.1 3e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 CEP19233.1 - 0.03 14.3 0.0 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) WYL_3 PF18488.1 CEP19233.1 - 0.087 13.2 0.7 0.23 11.9 0.7 1.6 1 0 0 1 1 1 0 WYL domain CLU PF13236.6 CEP19234.1 - 7.3e-83 277.8 0.1 2.3e-82 276.1 0.0 1.9 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 CEP19234.1 - 2.1e-48 164.7 1.6 3.2e-48 164.1 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CEP19234.1 - 1.1e-21 76.9 3.3 8.2e-09 35.6 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CEP19234.1 - 4.1e-21 74.2 1.0 3.5e-06 26.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat CLU_N PF15044.6 CEP19234.1 - 4e-18 65.5 0.1 2.4e-17 63.0 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 CEP19234.1 - 7e-09 35.7 0.0 2.3e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 CEP19234.1 - 0.12 12.6 6.6 22 5.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19234.1 - 0.19 12.0 1.6 5 7.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CEP19234.1 - 0.19 11.8 1.6 16 5.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CREPT PF16566.5 CEP19234.1 - 7.9 6.6 12.3 0.062 13.5 2.3 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour GST_C_3 PF14497.6 CEP19235.1 - 1.3e-18 67.0 0.1 1.2e-17 63.9 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP19235.1 - 8e-07 29.2 0.0 2e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP19235.1 - 0.00089 19.2 0.0 0.0027 17.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CEP19235.1 - 0.0058 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 CEP19235.1 - 0.02 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CEP19235.1 - 0.022 15.2 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Shikimate_dh_N PF08501.11 CEP19235.1 - 0.13 12.6 0.0 9.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain bZIP_2 PF07716.15 CEP19237.1 - 7.9e-06 25.9 15.9 4.5e-05 23.4 15.9 2.2 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CEP19237.1 - 3.8e-05 23.7 11.5 7.4e-05 22.8 11.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Spc42p PF11544.8 CEP19237.1 - 0.0052 16.8 0.9 0.0052 16.8 0.9 2.9 2 1 0 3 3 3 1 Spindle pole body component Spc42p bZIP_Maf PF03131.17 CEP19237.1 - 0.012 16.1 11.5 0.012 16.1 11.5 2.8 2 1 1 3 3 3 0 bZIP Maf transcription factor ZapB PF06005.12 CEP19237.1 - 0.11 13.0 17.7 0.31 11.5 7.2 3.5 3 1 1 4 4 4 0 Cell division protein ZapB YabA PF06156.13 CEP19237.1 - 1.1 10.0 8.6 0.14 12.8 3.7 2.0 2 1 1 3 3 3 0 Initiation control protein YabA V_ATPase_I PF01496.19 CEP19237.1 - 4.9 4.9 11.4 1.4 6.7 8.8 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Mon2_C PF16206.5 CEP19238.1 - 8.7e-90 302.0 1.7 1.6e-56 191.9 0.9 2.5 1 1 1 2 2 2 2 C-terminal region of Mon2 protein Sec7_N PF12783.7 CEP19238.1 - 3.7e-46 156.9 4.4 3.7e-46 156.9 4.4 4.7 6 1 1 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CEP19238.1 - 5.6e-39 133.6 14.6 6e-25 87.9 1.5 3.4 3 1 1 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CEP19238.1 - 0.00093 19.0 1.0 0.028 14.2 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF4519 PF15012.6 CEP19238.1 - 0.18 12.0 0.2 0.55 10.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DHODB_Fe-S_bind PF10418.9 CEP19239.1 - 0.0023 17.7 0.4 0.0051 16.6 0.4 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B OST-HTH PF12872.7 CEP19239.1 - 0.022 14.6 0.3 0.051 13.4 0.3 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Gti1_Pac2 PF09729.9 CEP19240.1 - 1.9e-50 171.5 0.3 1.9e-50 171.5 0.3 3.7 2 2 0 2 2 2 1 Gti1/Pac2 family WD40 PF00400.32 CEP19241.1 - 9.4e-38 127.6 24.8 8.1e-06 26.5 0.3 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19241.1 - 2.7e-18 66.0 3.3 0.013 15.8 0.0 6.6 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CEP19241.1 - 1.2e-08 34.6 0.4 2.4e-08 33.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 CEP19241.1 - 3.5e-07 29.9 0.2 0.00039 19.9 0.0 2.7 1 1 2 3 3 3 3 WD40-like domain Nup160 PF11715.8 CEP19241.1 - 2.4e-05 23.2 5.9 0.26 9.9 0.1 5.4 1 1 3 5 5 5 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CEP19241.1 - 0.00018 21.9 0.3 1.1e+02 3.4 0.0 6.1 6 1 1 7 7 7 0 PQQ-like domain PQQ_2 PF13360.6 CEP19241.1 - 0.00018 21.2 2.1 0.18 11.4 0.2 3.0 1 1 2 3 3 3 2 PQQ-like domain F-box PF00646.33 CEP19241.1 - 0.011 15.6 0.2 0.025 14.5 0.2 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_64 PF16483.5 CEP19241.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Beta-1,3-glucanase Sel_put PF04328.13 CEP19241.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 Selenoprotein, putative DUF4934 PF16288.5 CEP19241.1 - 0.085 12.8 0.2 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) Sulfate_transp PF00916.20 CEP19242.1 - 2.9e-97 325.8 19.4 4.1e-97 325.3 19.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CEP19242.1 - 9.4e-22 76.9 0.0 1.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CEP19242.1 - 0.0003 21.1 4.9 0.0003 21.1 4.9 3.1 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CEP19242.1 - 0.0016 18.7 0.1 0.059 13.7 0.0 2.4 2 0 0 2 2 2 1 STAS domain DUF2254 PF10011.9 CEP19242.1 - 0.0022 16.9 0.3 0.0052 15.6 0.3 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) TMEM174 PF15029.6 CEP19242.1 - 0.034 13.9 0.8 0.061 13.0 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 174 Methyltransf_16 PF10294.9 CEP19243.1 - 2.9e-36 124.8 0.1 3.7e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CEP19243.1 - 4.6e-05 23.0 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CEP19243.1 - 0.00071 19.1 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CEP19243.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEP19243.1 - 0.0031 17.3 0.0 0.0041 16.9 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CEP19243.1 - 0.0081 16.8 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19243.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 CEP19243.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G OrfB_Zn_ribbon PF07282.11 CEP19244.1 - 0.00018 21.4 0.0 0.0005 19.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain SUKH_6 PF14568.6 CEP19244.1 - 0.022 15.2 0.0 4.1 7.8 0.0 2.5 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall ATP-synt_F PF01990.17 CEP19245.1 - 1.8e-33 114.7 0.3 2.1e-33 114.5 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 CEP19245.1 - 0.071 12.3 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Eapp_C PF10238.9 CEP19246.1 - 1.1e-27 96.9 3.9 1.1e-27 96.9 3.9 1.9 1 1 1 2 2 2 1 E2F-associated phosphoprotein zinc_ribbon_10 PF10058.9 CEP19246.1 - 8.4 6.2 8.2 0.67 9.7 0.2 2.7 1 1 2 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Sec23_trunk PF04811.15 CEP19247.1 - 1.4e-59 201.6 0.0 2.3e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CEP19247.1 - 2.8e-20 72.9 0.0 7.1e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CEP19247.1 - 9.3e-17 60.7 0.8 1.9e-16 59.7 0.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEP19247.1 - 1e-12 47.9 4.7 1e-12 47.9 4.7 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CEP19247.1 - 0.00036 20.4 1.8 0.00082 19.2 0.0 2.6 3 0 0 3 3 3 1 Gelsolin repeat zf-C3HC4_3 PF13920.6 CEP19248.1 - 2.6e-06 27.2 7.6 2.6e-06 27.2 7.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CEP19248.1 - 0.045 14.2 0.4 0.045 14.2 0.4 5.7 6 1 0 6 6 6 0 Zinc finger, C2H2 type Not1 PF04054.15 CEP19249.1 - 7.7e-74 248.8 14.4 1e-73 248.4 14.4 1.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 FANCI_S2 PF14676.6 CEP19249.1 - 0.027 14.8 4.8 1.9 8.8 0.5 3.9 2 2 1 4 4 4 0 FANCI solenoid 2 Ras PF00071.22 CEP19250.1 - 1.4e-60 203.6 0.6 1.7e-60 203.3 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP19250.1 - 3.6e-35 120.8 0.1 5.1e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP19250.1 - 4.6e-14 52.2 0.1 6.2e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CEP19250.1 - 1.8e-05 24.8 0.1 2.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP19250.1 - 0.00013 21.6 0.1 0.00041 20.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP19250.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CEP19250.1 - 0.00034 20.5 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 CEP19250.1 - 0.0022 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 CEP19250.1 - 0.01 16.1 0.1 0.057 13.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 CEP19250.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CEP19250.1 - 0.032 14.7 0.5 0.068 13.7 0.5 1.8 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CEP19250.1 - 0.069 12.9 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CEP19250.1 - 0.073 13.0 0.3 0.16 11.8 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 CEP19250.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CEP19250.1 - 0.11 12.9 0.1 0.16 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CEP19250.1 - 0.13 12.2 0.1 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 CEP19251.1 - 1.3e-50 172.2 0.0 2.3e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19251.1 - 6.6e-35 120.6 0.0 9.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19251.1 - 1.6e-05 24.4 0.0 2.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CEP19251.1 - 0.00026 19.9 0.2 0.00062 18.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF1491 PF07372.12 CEP19251.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) FAD_binding_3 PF01494.19 CEP19252.1 - 4.9e-62 210.2 0.5 3.6e-61 207.4 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CEP19252.1 - 0.0039 17.7 0.1 0.95 10.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CEP19252.1 - 0.0054 15.5 0.1 0.058 12.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 CEP19252.1 - 0.017 14.2 0.0 0.048 12.7 0.0 1.7 2 1 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 CEP19252.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 CEP19252.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 CEP19252.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LRR_4 PF12799.7 CEP19253.1 - 6.6e-13 48.6 15.7 0.0013 19.1 0.0 5.7 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CEP19253.1 - 3.7e-09 36.3 0.0 1.3e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 CEP19253.1 - 2.8e-06 26.9 24.5 0.076 13.1 0.1 8.1 8 1 0 8 8 8 3 Leucine Rich repeat F-box PF00646.33 CEP19253.1 - 0.00092 19.0 0.0 0.00092 19.0 0.0 3.9 5 0 0 5 5 5 1 F-box domain LRR_8 PF13855.6 CEP19253.1 - 0.0016 18.1 14.5 5.4 6.9 0.0 5.2 5 2 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 CEP19253.1 - 0.012 16.1 22.1 3.5 8.5 2.4 7.7 7 2 0 7 7 7 0 Leucine Rich Repeat MFS_1 PF07690.16 CEP19254.1 - 5.2e-30 104.6 25.3 7.9e-30 104.0 25.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 CEP19254.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Methyltransf_11 PF08241.12 CEP19255.1 - 4.2e-06 27.3 0.0 0.0099 16.5 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19255.1 - 5.9e-06 26.2 0.0 3.1e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP19255.1 - 0.00013 22.6 0.1 0.52 11.1 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain DUF4227 PF14004.6 CEP19255.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Methyltransf_12 PF08242.12 CEP19255.1 - 0.16 12.7 0.0 1.2 9.9 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain PIP5K PF01504.18 CEP19256.1 - 0.06 12.6 0.1 0.075 12.2 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SWIRM-assoc_2 PF16496.5 CEP19256.1 - 0.062 12.2 1.4 0.07 12.0 1.4 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DDE_3 PF13358.6 CEP19257.1 - 1.8e-17 63.5 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP19257.1 - 0.03 13.3 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain UCH PF00443.29 CEP19258.1 - 1.9e-47 161.9 0.0 2.7e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CEP19258.1 - 1.7e-11 44.3 0.0 3.5e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Draxin PF15550.6 CEP19258.1 - 0.3 10.9 2.9 0.5 10.2 2.9 1.3 1 0 0 1 1 1 0 Draxin Ndc1_Nup PF09531.10 CEP19258.1 - 4.3 5.9 7.3 5.6 5.5 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SBDS_C PF09377.10 CEP19259.1 - 1.8e-37 127.9 1.0 1.8e-37 127.9 1.0 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 CEP19259.1 - 2.4e-34 117.3 1.0 4.5e-34 116.4 1.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.19 CEP19259.1 - 0.046 13.1 0.3 0.45 9.9 0.0 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_22 PF13309.6 CEP19259.1 - 0.059 13.5 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 HTH domain Csa1 PF06023.12 CEP19259.1 - 0.069 12.5 0.2 0.098 12.0 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 PapC_N PF13954.6 CEP19259.1 - 1.1 9.2 4.1 9 6.3 1.0 2.6 1 1 2 3 3 3 0 PapC N-terminal domain Mon1 PF03164.14 CEP19260.1 - 1.9e-103 346.7 7.4 8.7e-97 324.7 2.9 2.0 1 1 1 2 2 2 2 Trafficking protein Mon1 NMT1 PF09084.11 CEP19261.1 - 3.2e-09 37.0 0.0 5.6e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CEP19261.1 - 1.7e-06 27.9 0.0 1.5e-05 24.8 0.0 2.3 2 1 1 3 3 3 1 NMT1-like family Phosphonate-bd PF12974.7 CEP19261.1 - 9.4e-06 25.4 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 CEP19261.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DDHD PF02862.17 CEP19262.1 - 1.2e-27 97.5 11.3 1.2e-27 97.5 11.3 3.0 1 1 1 2 2 2 1 DDHD domain HMG_box PF00505.19 CEP19263.1 - 7.2e-20 71.2 9.0 5.1e-11 42.8 1.0 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP19263.1 - 1.1e-18 67.5 9.1 7.3e-12 45.7 1.0 2.9 2 1 0 2 2 2 2 HMG-box domain DUF1289 PF06945.13 CEP19263.1 - 0.25 11.2 5.6 4 7.3 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) Pkinase PF00069.25 CEP19264.1 - 1.5e-30 106.5 0.0 3.3e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kelch_5 PF13854.6 CEP19264.1 - 6.2e-15 54.8 11.3 1.2e-05 25.2 0.1 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CEP19264.1 - 2e-14 53.4 31.5 1.5e-06 28.3 0.7 7.5 8 0 0 8 8 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP19264.1 - 2.7e-14 52.9 16.9 9.3e-05 22.6 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CEP19264.1 - 2.9e-13 49.6 11.0 2.3e-05 24.3 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CEP19264.1 - 1.8e-11 43.4 15.2 0.015 14.9 0.3 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CEP19264.1 - 4.8e-10 39.0 13.8 0.0003 20.6 0.2 6.8 6 0 0 6 6 6 2 Kelch motif Pkinase_Tyr PF07714.17 CEP19264.1 - 1.3e-06 27.9 0.0 6.4e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19264.1 - 2e-06 27.4 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Herpes_gE PF02480.16 CEP19264.1 - 6.9e-06 25.1 0.0 1.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SUIM_assoc PF16619.5 CEP19264.1 - 0.013 15.5 37.3 0.11 12.6 0.1 4.2 4 0 0 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 EphA2_TM PF14575.6 CEP19264.1 - 0.1 13.5 4.2 0.5 11.3 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Sporozoite_P67 PF05642.11 CEP19264.1 - 1.2 7.1 13.4 0.03 12.4 3.5 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2681 PF10883.8 CEP19264.1 - 7.4 7.1 18.8 0.2 12.1 1.7 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) YajC PF02699.15 CEP19264.1 - 8.3 6.4 0.0 8.3 6.4 0.0 4.1 4 0 0 4 4 2 0 Preprotein translocase subunit CS PF04969.16 CEP19265.1 - 9.2e-20 71.4 0.1 1.6e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 CS domain DUF432 PF04254.13 CEP19265.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF432) adh_short_C2 PF13561.6 CEP19266.1 - 4.2e-64 216.3 0.6 5.3e-64 216.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP19266.1 - 3e-51 173.6 3.6 5.2e-51 172.9 3.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP19266.1 - 9.4e-15 55.0 0.4 1.5e-14 54.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP19266.1 - 0.0018 17.8 0.3 0.0028 17.2 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_1 PF00232.18 CEP19266.1 - 0.0073 14.8 0.0 0.0098 14.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SCO1-SenC PF02630.14 CEP19266.1 - 0.018 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC F420_oxidored PF03807.17 CEP19266.1 - 0.032 14.8 0.2 0.39 11.3 0.1 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent PX PF00787.24 CEP19268.1 - 1.5e-23 83.0 0.7 5.1e-23 81.2 0.2 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CEP19268.1 - 6e-19 68.5 12.3 3e-12 46.6 3.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 CEP19268.1 - 4.8e-07 29.7 10.8 5.6e-05 23.0 0.1 2.3 2 0 0 2 2 2 2 BAR domain of APPL family Sec34 PF04136.15 CEP19268.1 - 0.0004 20.3 6.9 0.0004 20.3 6.9 2.2 2 1 0 2 2 2 1 Sec34-like family Spidroin_N PF16763.5 CEP19268.1 - 0.0027 17.7 1.5 0.0027 17.7 1.5 2.1 2 1 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term Baculo_PEP_C PF04513.12 CEP19268.1 - 0.11 12.6 4.5 0.089 12.8 2.3 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rogdi_lz PF10259.9 CEP19268.1 - 0.12 11.8 2.0 0.2 11.1 0.9 1.8 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein Occludin_ELL PF07303.13 CEP19268.1 - 0.15 12.8 8.5 0.63 10.8 0.1 3.4 2 1 1 3 3 3 0 Occludin homology domain WD40_alt PF14077.6 CEP19268.1 - 0.19 11.6 1.2 8.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF724 PF05266.14 CEP19268.1 - 0.2 11.5 9.9 0.026 14.3 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PTRF_SDPR PF15237.6 CEP19268.1 - 0.23 11.0 4.4 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 PTRF/SDPR family GrpE PF01025.19 CEP19268.1 - 0.27 10.9 14.1 0.04 13.6 0.8 3.0 2 1 0 2 2 2 0 GrpE AdoHcyase PF05221.17 CEP19268.1 - 0.28 10.3 2.5 1.6 7.8 2.5 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase BAR_3_WASP_bdg PF10456.9 CEP19268.1 - 0.32 10.4 6.0 2.4 7.6 0.1 2.6 3 0 0 3 3 3 0 WASP-binding domain of Sorting nexin protein XhlA PF10779.9 CEP19268.1 - 0.86 9.9 5.5 15 5.9 0.9 2.7 2 0 0 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 CEP19268.1 - 1.6 7.6 9.7 0.19 10.6 4.7 1.7 1 1 0 2 2 2 0 LMBR1-like membrane protein NPV_P10 PF05531.12 CEP19268.1 - 1.6 9.3 3.8 14 6.2 0.6 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CEP19268.1 - 1.9 8.9 12.6 0.28 11.5 0.7 3.7 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dam1 PF08653.10 CEP19268.1 - 2.2 8.2 5.6 1.4 8.8 0.3 3.2 2 1 0 3 3 3 0 DASH complex subunit Dam1 FapA PF03961.13 CEP19268.1 - 4.4 5.8 7.6 0.74 8.3 2.4 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 CEP19268.1 - 4.5 7.5 8.4 0.52 10.6 1.4 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HTH_23 PF13384.6 CEP19269.1 - 0.00028 20.6 0.0 0.00081 19.1 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 CEP19269.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_psq PF05225.16 CEP19269.1 - 0.031 14.0 0.0 0.33 10.7 0.0 2.4 3 0 0 3 3 3 0 helix-turn-helix, Psq domain HTH_29 PF13551.6 CEP19269.1 - 0.084 12.9 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 CEP19269.1 - 0.095 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 CEP19269.1 - 0.12 12.6 0.0 0.74 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_37 PF13744.6 CEP19269.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain NDUFA12 PF05071.16 CEP19270.1 - 5.2e-28 97.7 2.5 6.2e-28 97.5 2.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 WD40 PF00400.32 CEP19271.1 - 7.5e-37 124.7 0.5 5.6e-05 23.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat FA_desaturase PF00487.24 CEP19271.1 - 8e-24 84.8 12.0 1.3e-23 84.1 12.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase ANAPC4_WD40 PF12894.7 CEP19271.1 - 7.9e-19 67.7 0.0 0.00049 20.3 0.0 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Lipid_DES PF08557.10 CEP19271.1 - 2.3e-09 36.6 0.3 4.6e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ge1_WD40 PF16529.5 CEP19271.1 - 1.5e-08 34.0 0.2 0.072 12.0 0.0 3.3 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CEP19271.1 - 1.7e-07 31.3 0.1 0.00034 20.5 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 CEP19271.1 - 3.1e-05 23.6 0.1 7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 CEP19271.1 - 0.00011 20.8 0.1 0.11 11.0 0.0 3.0 2 1 1 3 3 3 1 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 CEP19271.1 - 0.00046 19.2 0.1 0.35 9.8 0.0 3.1 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 CEP19271.1 - 0.0029 16.3 0.7 0.65 8.6 0.2 3.0 1 1 2 3 3 3 1 Nucleoporin Nup120/160 FH2 PF02181.23 CEP19272.1 - 1.1e-77 261.7 9.1 1.1e-77 261.7 9.1 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.13 CEP19272.1 - 1.9e-32 112.4 11.4 3.7e-28 98.4 0.0 4.4 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CEP19272.1 - 8e-22 77.8 0.1 8e-22 77.8 0.1 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain NanE PF04131.14 CEP19272.1 - 0.0024 17.1 0.1 0.0068 15.6 0.0 1.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase HALZ PF02183.18 CEP19272.1 - 0.042 14.1 0.5 0.042 14.1 0.5 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1843 PF08898.10 CEP19272.1 - 0.071 13.6 2.7 0.29 11.7 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) JIP_LZII PF16471.5 CEP19272.1 - 0.99 9.6 7.7 1.7 8.8 0.9 3.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF4145 PF13643.6 CEP19272.1 - 3.1 8.0 6.5 0.6 10.3 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) FUSC PF04632.12 CEP19272.1 - 9.3 4.6 8.0 1.1 7.7 0.0 2.5 3 0 0 3 3 3 0 Fusaric acid resistance protein family Lon_C PF05362.13 CEP19273.1 - 9.8e-74 247.3 0.6 2e-73 246.3 0.1 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CEP19273.1 - 1.6e-30 106.6 0.5 1.6e-30 106.6 0.5 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CEP19273.1 - 1.5e-23 83.7 0.0 9.2e-23 81.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 CEP19273.1 - 9.8e-06 25.4 0.0 2.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CEP19273.1 - 9.6e-05 22.4 0.0 0.00028 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CEP19273.1 - 0.00014 20.9 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 CEP19273.1 - 0.00043 20.6 0.0 0.039 14.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CEP19273.1 - 0.00078 19.2 0.1 0.003 17.3 0.0 2.0 3 0 0 3 3 1 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 CEP19273.1 - 0.0009 19.2 0.0 0.009 15.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CEP19273.1 - 0.0022 18.4 0.2 0.02 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CEP19273.1 - 0.0028 17.5 0.0 0.0091 15.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEP19273.1 - 0.0052 17.3 0.5 0.016 15.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CEP19273.1 - 0.012 15.8 0.0 0.091 12.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CEP19273.1 - 0.015 15.6 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CEP19273.1 - 0.025 14.7 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CEP19273.1 - 0.028 13.6 0.0 0.063 12.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 CEP19273.1 - 0.041 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2922 PF11148.8 CEP19273.1 - 0.074 12.8 0.1 0.27 11.0 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2922) NACHT PF05729.12 CEP19273.1 - 0.084 12.8 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ClpB_D2-small PF10431.9 CEP19273.1 - 0.09 12.9 0.0 0.41 10.7 0.0 2.1 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SKI PF01202.22 CEP19273.1 - 0.22 11.7 1.4 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Occludin_ELL PF07303.13 CEP19273.1 - 0.28 11.9 9.1 3 8.6 0.9 3.3 2 1 0 2 2 2 0 Occludin homology domain ABC_tran_Xtn PF12848.7 CEP19273.1 - 0.33 11.0 2.6 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CEP19273.1 - 1 9.8 0.0 1 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CEP19273.1 - 3.9 7.7 5.1 2.5 8.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain Polysacc_deac_1 PF01522.21 CEP19274.1 - 2.7e-35 121.0 0.0 4.9e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP19274.1 - 0.00044 19.6 0.1 0.0011 18.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 LytR_C PF13399.6 CEP19274.1 - 0.069 14.1 0.1 1.4 10.0 0.1 2.6 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator Pkinase PF00069.25 CEP19275.1 - 1.6e-39 135.9 0.1 3.2e-39 134.9 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19275.1 - 1.7e-14 53.7 0.1 5.1e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEP19275.1 - 5e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP19275.1 - 0.00015 20.7 0.0 0.00031 19.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CEP19275.1 - 0.00025 20.7 0.0 0.00055 19.6 0.0 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 CEP19275.1 - 0.00042 20.3 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP19275.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 CEP19275.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL TRAM_LAG1_CLN8 PF03798.16 CEP19276.1 - 3.9e-35 121.4 25.3 3.9e-35 121.4 25.3 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CEP19276.1 - 8.2e-17 60.6 0.8 2.6e-16 59.0 0.8 2.0 1 0 0 1 1 1 1 TRAM1-like protein DUF4834 PF16118.5 CEP19276.1 - 0.073 14.0 0.6 0.42 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 CEP19277.1 - 3.5e-63 213.5 0.0 4.7e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19277.1 - 2.4e-35 122.1 0.0 3.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CEP19277.1 - 2.3e-06 27.8 0.0 4.4e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CEP19277.1 - 0.00062 19.2 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Usp PF00582.26 CEP19278.1 - 1.3e-19 71.1 2.0 2.7e-19 70.1 0.0 2.4 2 1 0 2 2 2 1 Universal stress protein family Cupin_8 PF13621.6 CEP19279.1 - 2.5e-09 37.2 0.9 3.2e-09 36.9 0.9 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEP19279.1 - 0.00053 20.4 0.3 0.002 18.6 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase WD40 PF00400.32 CEP19282.1 - 3.6e-15 56.1 8.1 9.2e-05 23.1 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.25 CEP19283.1 - 1e-48 166.0 0.0 1.3e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19283.1 - 1.9e-15 56.8 0.2 6e-15 55.2 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19283.1 - 1.8e-05 24.2 0.0 4.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP19283.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP19283.1 - 0.018 15.0 0.0 0.046 13.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Usp PF00582.26 CEP19284.1 - 1.3e-17 64.6 0.0 1.6e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family YchF-GTPase_C PF06071.13 CEP19285.1 - 1.7e-26 92.2 0.0 6.2e-26 90.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CEP19285.1 - 6.6e-24 84.2 0.0 1.3e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP19285.1 - 3.5e-08 33.1 0.0 6.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEP19285.1 - 0.0013 18.8 0.1 0.86 9.6 0.0 3.1 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 CEP19285.1 - 0.014 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 CEP19285.1 - 0.12 12.1 0.0 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RRM_1 PF00076.22 CEP19286.1 - 8e-26 89.7 0.0 2.2e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CEP19286.1 - 3.1e-20 70.6 0.0 1.7e-05 24.2 0.0 6.4 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 CEP19286.1 - 0.00025 20.9 0.0 1.4 8.8 0.0 2.9 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 CEP19286.1 - 0.053 13.6 0.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif bZIP_2 PF07716.15 CEP19287.1 - 0.00034 20.6 13.0 0.00034 20.6 13.0 4.1 3 1 0 4 4 4 1 Basic region leucine zipper YabA PF06156.13 CEP19287.1 - 0.35 11.5 8.2 0.18 12.4 1.0 3.1 3 0 0 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 CEP19287.1 - 7.1 6.8 26.9 0.16 12.1 7.8 3.0 3 0 0 3 3 3 0 bZIP transcription factor DUF3605 PF12239.8 CEP19289.1 - 3.9e-27 95.5 3.1 3e-25 89.4 3.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DPBB_1 PF03330.18 CEP19290.1 - 8.7e-06 25.9 0.4 2.9e-05 24.3 0.2 2.1 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CEP19290.1 - 1.1e-05 25.3 0.3 1.7e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 Barwin family DUF871 PF05913.11 CEP19290.1 - 0.0013 18.1 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF871) ANTH PF07651.16 CEP19291.1 - 1.1e-49 168.9 4.7 1.5e-49 168.4 4.7 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CEP19291.1 - 2.4e-08 34.0 0.1 5e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 ENTH domain HTH_29 PF13551.6 CEP19292.1 - 1.2e-05 25.2 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 CEP19292.1 - 7.5e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 CEP19292.1 - 0.0016 18.2 0.0 0.0058 16.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CEP19292.1 - 0.0045 16.6 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 DUF3486 PF11985.8 CEP19292.1 - 0.052 14.0 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) HTH_17 PF12728.7 CEP19292.1 - 0.11 12.7 0.4 1.5 9.1 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain PDDEXK_2 PF12784.7 CEP19293.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase DUF2887 PF11103.8 CEP19293.1 - 0.18 11.8 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) GCP_N_terminal PF17681.1 CEP19294.1 - 6e-43 147.6 0.6 1e-42 146.9 0.1 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CEP19294.1 - 2.2e-30 106.2 9.3 4.1e-30 105.3 9.3 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF5427 PF10310.9 CEP19295.1 - 4.5e-49 167.7 25.5 1.8e-45 155.8 19.4 2.6 2 1 0 2 2 2 2 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 CEP19295.1 - 0.57 8.8 9.6 0.66 8.6 9.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short PF00106.25 CEP19296.1 - 4.1e-48 163.4 1.5 5.9e-48 162.9 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP19296.1 - 3.5e-41 141.3 0.4 5.2e-41 140.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP19296.1 - 1.4e-05 25.1 1.4 2.5e-05 24.3 1.4 1.3 1 0 0 1 1 1 1 KR domain YlzJ PF14035.6 CEP19297.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 YlzJ-like protein zf-RVT PF13966.6 CEP19298.1 - 4.1e-07 30.6 1.1 7.9e-07 29.7 1.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PGAP1 PF07819.13 CEP19299.1 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CEP19299.1 - 2.6e-05 24.2 0.1 7.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CEP19299.1 - 2.7e-05 23.8 0.2 0.00044 19.8 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 CEP19299.1 - 0.00019 21.2 0.3 0.0011 18.7 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CEP19299.1 - 0.00075 20.2 0.0 0.001 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CEP19299.1 - 0.0042 16.3 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase ABC1 PF03109.16 CEP19300.1 - 3.9e-31 107.7 0.1 7.4e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CEP19300.1 - 2.4e-05 24.0 0.1 6.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 CEP19300.1 - 0.0058 16.0 0.1 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain AAR2 PF05282.11 CEP19300.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 AAR2 protein APH PF01636.23 CEP19300.1 - 0.018 15.0 0.1 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Yip1 PF04893.17 CEP19301.1 - 1.3e-15 57.6 16.8 1.2e-14 54.4 16.8 2.0 1 1 0 1 1 1 1 Yip1 domain Reovirus_L2 PF06016.11 CEP19301.1 - 0.021 12.0 0.0 0.025 11.8 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) DUF5600 PF18150.1 CEP19302.1 - 1.8e-40 137.8 1.0 3.9e-40 136.7 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 CEP19302.1 - 2.9e-20 72.1 0.0 2.1e-19 69.4 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 CEP19302.1 - 6.6e-14 52.3 0.0 9.5e-13 48.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 CEP19302.1 - 7.3e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 CEP19302.1 - 2.5e-08 34.0 0.0 6.8e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CEP19302.1 - 9.5e-06 24.8 0.2 4.1e-05 22.8 0.2 2.2 1 0 0 1 1 1 1 EF hand GTP_EFTU PF00009.27 CEP19302.1 - 1.2e-05 25.0 0.0 2.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CEP19302.1 - 2.2e-05 23.9 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_7 PF13499.6 CEP19302.1 - 8.3e-05 23.0 2.5 0.011 16.2 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP19302.1 - 0.00031 20.5 0.0 0.0023 17.7 0.1 2.5 3 0 0 3 3 3 1 EF-hand domain Roc PF08477.13 CEP19302.1 - 0.00042 20.5 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 CEP19302.1 - 0.00063 19.5 0.4 0.017 15.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair FeoB_N PF02421.18 CEP19302.1 - 0.0015 18.1 0.0 0.053 13.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 CEP19302.1 - 0.043 13.3 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CEP19302.1 - 0.077 13.4 0.1 0.4 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain VCBS PF13517.6 CEP19302.1 - 0.099 13.3 0.3 0.24 12.0 0.3 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AAA_28 PF13521.6 CEP19302.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CEP19302.1 - 0.14 12.2 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AIG1 PF04548.16 CEP19302.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Ras PF00071.22 CEP19302.1 - 0.15 11.7 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Ras family Actin PF00022.19 CEP19303.1 - 4.1e-151 503.2 0.0 1.6e-150 501.3 0.0 1.7 1 1 0 1 1 1 1 Actin Ecl1 PF12855.7 CEP19305.1 - 4.3e-11 44.3 10.1 4.7e-11 44.2 10.1 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CEP19305.1 - 0.09 12.9 6.8 0.18 11.9 6.8 1.5 1 1 0 1 1 1 0 MYND finger DUF2116 PF09889.9 CEP19305.1 - 1.4 9.0 6.0 2.2 8.3 6.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Malic_M PF03949.15 CEP19306.1 - 6.5e-84 281.2 0.1 8.7e-84 280.8 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CEP19306.1 - 1e-55 188.4 0.0 1.7e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RGS PF00615.19 CEP19307.1 - 1.9e-10 41.0 0.6 1.6e-09 38.0 0.6 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain G_glu_transpept PF01019.21 CEP19308.1 - 2.2e-30 105.9 0.0 2.6e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GLTSCR1 PF15249.6 CEP19311.1 - 6.1e-25 87.6 0.4 6.1e-25 87.6 0.4 3.6 3 1 0 3 3 3 1 Conserved region of unknown function on GLTSCR protein Couple_hipA PF13657.6 CEP19311.1 - 0.39 11.4 2.9 2.3 8.9 0.7 2.9 2 0 0 2 2 2 0 HipA N-terminal domain SNase PF00565.17 CEP19312.1 - 6.7e-17 61.9 0.1 3.9e-15 56.2 0.1 2.3 1 1 0 1 1 1 1 Staphylococcal nuclease homologue DUF2456 PF10445.9 CEP19312.1 - 0.086 12.9 0.3 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DnaJ PF00226.31 CEP19313.1 - 1.4e-20 73.2 3.1 3.7e-20 71.8 3.1 1.8 1 0 0 1 1 1 1 DnaJ domain Vac_ImportDeg PF09783.9 CEP19314.1 - 2.4e-57 193.3 1.9 2.4e-57 193.3 1.9 1.4 2 0 0 2 2 2 1 Vacuolar import and degradation protein CENP-S PF15630.6 CEP19315.1 - 4.7e-19 68.5 0.7 9e-19 67.6 0.7 1.6 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CEP19315.1 - 1.4e-06 28.4 0.4 1.9e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CEP19315.1 - 0.057 13.4 0.5 0.13 12.3 0.4 1.6 1 1 0 1 1 1 0 Bromodomain associated Use1 PF09753.9 CEP19316.1 - 0.026 14.3 3.0 0.032 14.0 3.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Polysacc_deac_1 PF01522.21 CEP19317.1 - 3e-33 114.3 0.0 4.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP19317.1 - 3.4e-06 26.5 0.0 4.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Cyclin PF08613.11 CEP19318.1 - 3.6e-13 50.2 0.3 3.6e-13 50.2 0.3 1.8 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CEP19318.1 - 5.5e-05 22.9 1.0 0.0001 22.1 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mlf1IP PF10248.9 CEP19318.1 - 0.046 13.7 0.6 0.068 13.1 0.6 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein A_deamin PF02137.18 CEP19319.1 - 1.3e-60 205.6 0.1 1.1e-58 199.2 0.1 2.1 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain RNB PF00773.19 CEP19320.1 - 1.1e-70 238.6 0.0 2.6e-70 237.4 0.0 1.7 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEP19320.1 - 2.5e-21 75.5 0.0 5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CEP19320.1 - 2.1e-12 47.2 2.7 3.2e-12 46.6 0.0 2.7 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 CEP19320.1 - 0.02 14.6 0.0 0.02 14.6 0.0 2.5 3 0 0 3 3 3 0 Rrp44-like cold shock domain SUIM_assoc PF16619.5 CEP19320.1 - 0.11 12.6 35.1 0.52 10.4 7.1 4.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ArfGap PF01412.18 CEP19321.1 - 5.3e-36 123.2 0.0 2e-35 121.4 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CotH PF08757.11 CEP19322.1 - 1.9e-32 113.1 0.8 1.9e-32 113.1 0.8 1.4 2 0 0 2 2 2 1 CotH kinase protein rve PF00665.26 CEP19323.1 - 2.7e-06 27.5 0.0 7.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF5600 PF18150.1 CEP19323.1 - 0.0061 17.1 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Exo_endo_phos_2 PF14529.6 CEP19324.1 - 6.3e-09 35.7 0.1 7.7e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Helitron_like_N PF14214.6 CEP19325.1 - 8.6e-15 55.4 0.3 1.6e-14 54.6 0.1 1.5 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 CEP19328.1 - 2.9e-26 92.9 0.0 3.9e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP19329.1 - 1.4e-39 136.3 0.2 6.1e-21 75.0 0.1 3.6 1 1 2 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CEP19329.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.6 CEP19331.1 - 0.003 17.5 8.8 0.0038 17.1 8.8 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 DUF5327 PF17261.2 CEP19331.1 - 0.01 16.5 18.2 0.018 15.7 18.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5327) TFIIA PF03153.13 CEP19331.1 - 0.013 15.5 32.9 0.013 15.5 32.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CEP19331.1 - 0.025 14.2 37.8 0.034 13.7 37.8 1.3 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 CEP19331.1 - 0.029 15.0 18.1 0.036 14.7 18.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dicty_REP PF05086.12 CEP19331.1 - 0.043 11.8 9.9 0.043 11.8 9.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Baculo_PP31 PF05311.11 CEP19331.1 - 0.059 12.8 10.6 0.069 12.6 10.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.12 CEP19331.1 - 0.064 12.2 16.1 0.064 12.2 16.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 CEP19331.1 - 0.067 13.4 7.4 0.071 13.3 7.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ORC_WH_C PF18137.1 CEP19331.1 - 0.081 13.0 12.0 0.11 12.6 12.0 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal PPL5 PF18168.1 CEP19331.1 - 0.084 12.2 9.5 0.1 11.9 9.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 TERB2 PF15101.6 CEP19331.1 - 0.089 12.8 16.7 0.099 12.7 16.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CDC45 PF02724.14 CEP19331.1 - 0.12 10.6 11.9 0.13 10.6 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 CEP19331.1 - 0.14 12.3 9.9 0.15 12.2 9.9 1.1 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 CEP19331.1 - 0.15 11.1 8.2 0.16 11.0 8.2 1.1 1 0 0 1 1 1 0 CLN3 protein Pannexin_like PF12534.8 CEP19331.1 - 0.27 10.3 9.0 0.31 10.1 9.0 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 RR_TM4-6 PF06459.12 CEP19331.1 - 0.35 10.7 11.0 0.36 10.6 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CEP19331.1 - 0.36 10.2 13.8 0.4 10.1 13.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1980 PF09323.10 CEP19331.1 - 0.44 10.4 6.5 0.49 10.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AIF_C PF14721.6 CEP19331.1 - 0.46 10.8 7.3 0.58 10.5 7.3 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Neur_chan_memb PF02932.16 CEP19331.1 - 0.54 10.3 10.5 0.59 10.1 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 CEP19331.1 - 0.54 9.6 19.3 0.62 9.4 19.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 CEP19331.1 - 0.56 8.9 15.6 0.62 8.8 15.6 1.0 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 CEP19331.1 - 0.63 8.9 5.4 0.64 8.9 5.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIIBC-GUT_N PF03612.14 CEP19331.1 - 0.64 9.7 8.6 0.73 9.6 8.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.9 CEP19331.1 - 0.74 8.0 23.6 0.76 8.0 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.6 CEP19331.1 - 0.76 8.1 6.7 0.82 8.0 6.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2828 PF11443.8 CEP19331.1 - 0.96 7.5 12.5 1.1 7.3 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FliP PF00813.20 CEP19331.1 - 1.1 9.2 3.8 1.1 9.1 3.8 1.2 1 0 0 1 1 1 0 FliP family DNApol_Exo PF18136.1 CEP19331.1 - 1.1 8.3 12.5 1.3 8.1 12.5 1.0 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Ureide_permease PF07168.11 CEP19331.1 - 1.1 7.9 3.7 1.3 7.7 3.7 1.1 1 0 0 1 1 1 0 Ureide permease Band_3_cyto PF07565.13 CEP19331.1 - 1.2 8.9 12.0 1.4 8.6 12.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM176 PF14851.6 CEP19331.1 - 1.5 8.5 7.7 2 8.1 7.7 1.3 1 0 0 1 1 1 0 FAM176 family Paramyxo_ncap PF00973.19 CEP19331.1 - 1.6 7.6 9.6 1.6 7.5 9.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4175 PF13779.6 CEP19331.1 - 1.6 6.5 35.6 1.6 6.5 35.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OATP PF03137.20 CEP19331.1 - 1.8 6.8 6.1 1.9 6.7 6.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ndc1_Nup PF09531.10 CEP19331.1 - 1.8 7.2 10.7 1.9 7.1 10.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Connexin PF00029.19 CEP19331.1 - 1.9 8.2 9.6 2.2 8.0 9.6 1.1 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 CEP19331.1 - 2.1 7.3 16.3 2.3 7.1 16.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Folate_carrier PF01770.18 CEP19331.1 - 2.2 6.9 4.2 2.3 6.9 4.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier PepSY_TM PF03929.16 CEP19331.1 - 2.4 7.7 5.8 2.6 7.6 5.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Bud13 PF09736.9 CEP19331.1 - 2.5 8.5 20.1 3.3 8.1 20.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex UPF0560 PF10577.9 CEP19331.1 - 2.9 6.3 18.6 2.9 6.3 18.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ALMT PF11744.8 CEP19331.1 - 3.2 6.5 12.3 3.5 6.4 12.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 CEP19331.1 - 3.3 7.8 12.0 3.8 7.6 12.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Ctr PF04145.15 CEP19331.1 - 3.4 8.3 6.8 3.9 8.1 6.8 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Membralin PF09746.9 CEP19331.1 - 3.6 6.5 9.5 3.6 6.5 9.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein V_ATPase_I PF01496.19 CEP19331.1 - 4.2 5.2 18.6 3.1 5.6 17.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family O-antigen_lig PF13425.6 CEP19331.1 - 5.9 5.6 5.9 6.1 5.5 5.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HCO3_cotransp PF00955.21 CEP19331.1 - 5.9 5.6 4.9 6.4 5.5 4.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family EOS1 PF12326.8 CEP19331.1 - 6.6 6.6 6.9 8 6.4 6.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Mem_trans PF03547.18 CEP19331.1 - 6.9 5.0 5.2 7.2 4.9 5.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Herpes_UL32 PF06070.11 CEP19331.1 - 6.9 4.3 14.3 7.9 4.1 14.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Exonuc_VII_L PF02601.15 CEP19331.1 - 7.1 6.1 19.6 7.4 6.0 19.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cellulose_synt PF03552.14 CEP19331.1 - 7.2 5.0 6.2 7.7 4.9 6.2 1.1 1 0 0 1 1 1 0 Cellulose synthase DDE_Tnp_1_7 PF13843.6 CEP19333.1 - 1.8e-26 93.3 0.0 3.2e-26 92.5 0.0 1.4 1 1 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CEP19333.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_5 PF13546.6 CEP19333.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease PIF1 PF05970.14 CEP19335.1 - 4.8e-20 72.0 0.0 1.3e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase MLVIN_C PF18697.1 CEP19335.1 - 2.3e-05 24.4 0.1 5e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Herpes_Helicase PF02689.14 CEP19335.1 - 0.00038 18.5 0.0 0.00053 18.1 0.0 1.1 1 0 0 1 1 1 1 Helicase BAH PF01426.18 CEP19335.1 - 0.077 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.14 CEP19336.1 - 2.3e-69 234.3 0.0 3.6e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP19336.1 - 5.9e-07 29.4 0.0 9.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CEP19336.1 - 9.1e-05 22.5 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EF-hand_11 PF08976.11 CEP19336.1 - 0.0034 18.2 0.0 4.6 8.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain AAA_16 PF13191.6 CEP19336.1 - 0.0036 17.7 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CEP19336.1 - 0.004 17.2 0.0 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CEP19336.1 - 0.0046 17.3 0.0 0.013 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CEP19336.1 - 0.013 15.3 0.1 0.013 15.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CEP19336.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CEP19336.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 CEP19336.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bac_GH3_C PF18034.1 CEP19336.1 - 0.05 13.4 0.1 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain RNA_helicase PF00910.22 CEP19336.1 - 0.053 13.9 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CEP19336.1 - 0.075 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) mCpol PF18182.1 CEP19336.1 - 0.082 13.2 0.3 39 4.6 0.0 3.5 4 0 0 4 4 4 0 minimal CRISPR polymerase domain DUF2075 PF09848.9 CEP19336.1 - 0.091 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CEP19336.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CEP19336.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 CEP19336.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TrwB_AAD_bind PF10412.9 CEP19336.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 CEP19336.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_2 PF03668.15 CEP19336.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop ATPase protein family DDE_3 PF13358.6 CEP19339.1 - 2.2e-10 40.5 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ACT_3 PF10000.9 CEP19339.1 - 0.08 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 ACT domain HTH_Tnp_Tc5 PF03221.16 CEP19340.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DNA_pol_A_exo1 PF01612.20 CEP19341.1 - 0.014 15.2 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 3'-5' exonuclease PmrD PF11183.8 CEP19341.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD OrfB_Zn_ribbon PF07282.11 CEP19343.1 - 0.00064 19.6 1.4 0.0011 18.8 1.4 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Bmp PF02608.14 CEP19343.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like Rib_5-P_isom_A PF06026.14 CEP19344.1 - 1e-59 201.0 0.0 1.3e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF1279 PF06916.13 CEP19345.1 - 4.6e-15 55.9 0.1 1e-14 54.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Molydop_binding PF01568.21 CEP19345.1 - 0.067 13.2 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF4620 PF15399.6 CEP19345.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DUF2273 PF10031.9 CEP19345.1 - 0.096 12.7 0.4 0.096 12.7 0.4 2.0 2 1 0 2 2 2 0 Small integral membrane protein (DUF2273) WD40 PF00400.32 CEP19346.1 - 3.2e-38 129.0 30.9 2.9e-06 27.9 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 CEP19346.1 - 1.1e-10 40.8 9.9 0.032 12.9 0.1 5.4 5 1 1 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 CEP19346.1 - 3.2e-07 30.1 1.0 6.9e-07 29.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CEP19346.1 - 4e-07 30.3 1.9 0.22 11.8 0.0 5.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CEP19346.1 - 3.7e-06 26.7 0.8 8e-06 25.6 0.8 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CEP19346.1 - 6e-05 22.5 0.0 0.00032 20.1 0.0 2.4 1 1 0 1 1 1 1 WD40-like domain F-box_4 PF15966.5 CEP19346.1 - 0.0002 21.2 0.5 0.00052 19.9 0.5 1.7 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 CEP19346.1 - 0.0044 16.6 0.2 0.014 15.0 0.2 1.8 1 1 0 1 1 1 1 PQQ-like domain HSP70 PF00012.20 CEP19347.1 - 1e-168 562.3 6.6 1e-168 562.3 6.6 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CEP19347.1 - 6.4e-12 44.9 1.2 3.3e-11 42.6 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Thi4 PF01946.17 CEP19347.1 - 0.11 11.7 0.1 0.73 9.0 0.0 2.1 1 1 1 2 2 2 0 Thi4 family Ketoacyl-synt_C PF02801.22 CEP19347.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain DNA_pol_D_N PF18018.1 CEP19348.1 - 4.1e-05 23.7 0.6 0.0028 17.8 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase delta subunit OB-fold domain GATase_7 PF13537.6 CEP19349.1 - 4.1e-14 52.5 0.0 7.6e-14 51.7 0.0 1.4 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CEP19349.1 - 4.3e-14 52.8 0.0 7.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 CEP19350.1 - 2e-95 320.5 0.2 4.8e-58 197.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CEP19350.1 - 3.3e-15 56.1 0.0 6.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CEP19350.1 - 7.1e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 CEP19350.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 CEP19350.1 - 0.023 13.8 0.0 0.056 12.6 0.0 1.6 2 0 0 2 2 2 0 NAD synthase QueC PF06508.13 CEP19350.1 - 0.097 12.2 0.1 0.24 10.8 0.1 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC GATA PF00320.27 CEP19351.1 - 4.5e-15 55.0 4.2 4.5e-15 55.0 4.2 2.4 2 0 0 2 2 2 1 GATA zinc finger zf-RRN7 PF11781.8 CEP19351.1 - 0.00057 19.5 7.8 0.0046 16.6 0.2 3.0 2 1 1 3 3 3 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LAMTOR PF15454.6 CEP19351.1 - 0.02 15.5 1.2 0.02 15.5 1.2 3.3 4 0 0 4 4 4 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Zn-ribbon_8 PF09723.10 CEP19351.1 - 0.023 14.8 3.1 1.8 8.7 0.1 3.1 2 0 0 2 2 2 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CEP19351.1 - 0.036 13.6 0.2 0.036 13.6 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding HALZ PF02183.18 CEP19351.1 - 0.045 14.0 0.5 0.045 14.0 0.5 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Apocytochr_F_N PF16639.5 CEP19351.1 - 0.059 13.7 1.1 0.22 11.8 0.2 2.1 1 1 1 2 2 2 0 Apocytochrome F, N-terminal eIF-5_eIF-2B PF01873.17 CEP19351.1 - 0.072 13.0 1.9 0.26 11.2 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TGF_beta_GS PF08515.12 CEP19351.1 - 0.24 10.9 3.4 0.69 9.5 3.4 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Hydin_ADK PF17213.3 CEP19351.1 - 2.2 8.5 8.2 10 6.3 3.5 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF2607 PF10795.9 CEP19351.1 - 2.9 8.1 12.2 0.22 11.7 6.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2607) DDE_3 PF13358.6 CEP19352.1 - 1.4e-12 47.6 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Lactamase_B_6 PF16661.5 CEP19353.1 - 3e-08 33.4 0.0 3e-08 33.4 0.0 3.0 5 0 0 5 5 5 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CEP19353.1 - 2.9e-05 24.3 0.0 0.00021 21.6 0.0 2.5 1 0 0 1 1 1 1 Beta-Casp domain COE1_HLH PF16423.5 CEP19353.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Carboxyl_trans PF01039.22 CEP19353.1 - 0.45 9.1 0.0 0.45 9.1 0.0 2.0 2 0 0 2 2 2 0 Carboxyl transferase domain Thg1 PF04446.12 CEP19354.1 - 6.7e-52 174.8 0.3 1.1e-51 174.1 0.3 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CEP19354.1 - 1.7e-42 144.4 0.1 2.7e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Peptidase_S10 PF00450.22 CEP19355.1 - 2.6e-88 297.2 1.1 2.9e-88 297.1 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_Tnp_IS91 PF14319.6 CEP19355.1 - 0.027 14.5 0.2 0.051 13.6 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DNase-RNase PF02577.14 CEP19356.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease DUF2561 PF10812.8 CEP19356.1 - 0.11 12.6 0.8 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF2721 PF11026.8 CEP19356.1 - 0.15 12.0 1.1 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF202 PF02656.15 CEP19356.1 - 2.7 8.5 12.8 8.1 7.0 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) TRAPP PF04051.16 CEP19357.1 - 1.8e-38 131.5 0.0 2.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 CEP19357.1 - 0.069 13.4 0.0 11 6.4 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Carboxyl_trans PF01039.22 CEP19358.1 - 3.7e-141 471.2 0.0 4.9e-141 470.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_2 PF16113.5 CEP19359.1 - 1.3e-72 245.1 0.0 1.6e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEP19359.1 - 6.5e-23 81.3 0.0 5.7e-21 75.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Hydrolase_3 PF08282.12 CEP19359.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ECH_2 PF16113.5 CEP19360.1 - 1.9e-45 155.8 0.0 2.6e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CEP19360.1 - 1.2e-08 34.5 0.0 2e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SET PF00856.28 CEP19361.1 - 0.0005 20.5 0.0 0.00081 19.8 0.0 1.4 1 1 0 1 1 1 1 SET domain RRM_1 PF00076.22 CEP19362.1 - 7.2e-30 102.6 0.2 1.4e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP19362.1 - 3.8e-06 26.9 0.2 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.8 CEP19362.1 - 0.0002 21.3 1.7 0.1 12.7 0.1 2.3 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.15 CEP19362.1 - 0.002 18.1 0.4 0.86 9.6 0.1 2.4 2 1 0 2 2 2 2 DbpA RNA binding domain RRM_5 PF13893.6 CEP19362.1 - 0.018 14.7 0.0 2.6 7.6 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CEP19362.1 - 0.19 11.4 0.1 0.6 9.8 0.1 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated NGF PF00243.18 CEP19363.1 - 0.044 14.0 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Nerve growth factor family YtxC PF08812.11 CEP19364.1 - 0.0093 15.6 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 YtxC-like family DUF2490 PF10677.9 CEP19364.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) Ras PF00071.22 CEP19365.1 - 2.7e-53 179.9 0.0 3.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP19365.1 - 1.8e-19 70.1 0.0 2.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP19365.1 - 1.4e-07 31.1 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP19365.1 - 0.05 13.1 0.1 0.3 10.6 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AATase PF07247.12 CEP19366.1 - 3.4e-21 75.4 0.0 4.3e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.20 CEP19366.1 - 3.1e-13 49.2 3.0 1.2e-10 40.7 1.3 2.6 3 0 0 3 3 3 2 Condensation domain Transferase PF02458.15 CEP19366.1 - 0.025 13.2 0.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Transferase family Mito_carr PF00153.27 CEP19367.1 - 2.5e-61 203.6 0.1 4.6e-22 77.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CEP19367.1 - 0.079 12.1 0.1 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease MBOAT_2 PF13813.6 CEP19368.1 - 1.8e-18 66.6 0.2 4.7e-18 65.2 0.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Insulin_TMD PF17870.1 CEP19368.1 - 0.015 15.4 0.1 0.56 10.3 0.0 2.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FGGY_N PF00370.21 CEP19369.1 - 8.4e-24 84.5 0.0 1.6e-21 77.0 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CEP19369.1 - 2.9e-19 69.6 0.0 6.5e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain WD40 PF00400.32 CEP19370.1 - 4.9e-39 131.6 31.3 8.3e-06 26.5 1.0 13.4 13 1 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19370.1 - 0.00017 21.8 11.1 7.7 6.9 0.2 7.0 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CEP19370.1 - 0.049 12.4 0.8 0.78 8.4 0.1 2.9 3 0 0 3 3 3 0 Nup133 N terminal like CK2S PF15011.6 CEP19371.1 - 8.7e-26 90.7 3.3 8.7e-26 90.7 3.3 1.5 2 0 0 2 2 2 1 Casein Kinase 2 substrate OHCU_decarbox PF09349.10 CEP19371.1 - 0.00095 19.7 1.9 0.0043 17.5 1.7 2.1 1 1 1 2 2 2 1 OHCU decarboxylase RcsF PF16358.5 CEP19371.1 - 0.11 12.6 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 RcsF lipoprotein Ribosomal_L2_C PF03947.18 CEP19372.1 - 5.9e-46 155.8 3.7 5.9e-46 155.8 3.7 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CEP19372.1 - 1.6e-15 56.8 0.1 4.1e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ThiF PF00899.21 CEP19373.1 - 7.7e-40 136.8 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CEP19373.1 - 0.0001 22.6 1.0 0.00092 19.5 1.0 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 CEP19373.1 - 0.0056 16.0 0.1 0.0089 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 CEP19373.1 - 0.02 14.9 0.3 0.052 13.6 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CEP19373.1 - 0.032 13.5 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CEP19373.1 - 0.039 13.5 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 CEP19373.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 CEP19373.1 - 0.1 13.0 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 CEP19373.1 - 0.11 12.1 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase CagA PF03507.13 CEP19373.1 - 0.16 11.9 0.6 0.36 10.8 0.1 1.9 2 1 0 2 2 2 0 CagA exotoxin Adaptin_N PF01602.20 CEP19374.1 - 6.6e-115 384.6 1.6 8.8e-115 384.2 1.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CEP19374.1 - 1.2e-57 194.3 0.6 2.7e-57 193.2 0.6 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CEP19374.1 - 3.1e-31 107.9 0.0 7.1e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CEP19374.1 - 3.4e-20 72.2 0.0 2.1e-09 37.6 0.0 5.7 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 CEP19374.1 - 6.5e-10 39.3 4.6 0.0068 16.5 0.0 5.2 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP19374.1 - 0.004 17.3 4.5 28 5.3 0.2 6.2 7 0 0 7 7 7 0 HEAT repeat Rad60-SLD_2 PF13881.6 CEP19374.1 - 0.014 15.5 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HEAT_PBS PF03130.16 CEP19374.1 - 0.12 13.2 8.9 1.4 9.8 0.0 5.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 CEP19374.1 - 0.13 12.4 0.6 15 5.8 0.0 3.7 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Pex2_Pex12 PF04757.14 CEP19375.1 - 4.4e-49 167.1 6.3 5.4e-49 166.8 6.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CEP19375.1 - 1e-06 28.5 0.5 1.5e-06 27.9 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP19375.1 - 0.00011 22.4 1.3 0.00019 21.7 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CEP19375.1 - 0.00058 19.6 1.2 0.001 18.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CEP19375.1 - 0.0033 17.3 1.0 0.0055 16.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CEP19375.1 - 0.012 15.8 5.3 0.022 14.9 5.3 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CEP19375.1 - 0.023 14.7 3.7 0.047 13.7 3.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RRPl_C4 PF17026.5 CEP19375.1 - 0.06 13.5 0.4 0.1 12.7 0.4 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 CEP19375.1 - 0.093 12.8 1.1 0.16 12.0 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Tubulin PF00091.25 CEP19376.1 - 5.9e-71 238.8 0.0 1e-70 238.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CEP19376.1 - 1.2e-40 138.6 0.1 1.8e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CEP19376.1 - 9.5e-06 25.9 0.0 2.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CEP19376.1 - 0.036 13.3 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 CEP19376.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain SLX9 PF15341.6 CEP19377.1 - 1.6e-20 73.9 19.8 1.6e-20 73.9 19.8 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Folliculin PF11704.8 CEP19377.1 - 3.4 7.5 8.1 5.6 6.8 8.1 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Neur_chan_memb PF02932.16 CEP19377.1 - 5.4 7.0 6.9 6.3 6.8 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aminotran_1_2 PF00155.21 CEP19378.1 - 2.6e-75 253.9 0.0 3.1e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CEP19378.1 - 1.1e-06 27.5 0.0 1.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Preseq_ALAS PF09029.10 CEP19378.1 - 0.00015 22.2 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Aminotran_5 PF00266.19 CEP19378.1 - 0.00049 19.2 0.0 0.0011 17.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CEP19378.1 - 0.0019 17.6 0.1 0.0046 16.3 0.1 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase HAMP_N3 PF18575.1 CEP19379.1 - 0.11 12.1 0.4 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 HAMP N-terminal domain 3 PAS_3 PF08447.12 CEP19380.1 - 4e-23 81.5 0.0 7.9e-12 45.3 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_9 PF13426.7 CEP19380.1 - 6.3e-22 77.8 0.0 4.2e-17 62.3 0.0 3.3 2 1 1 3 3 3 2 PAS domain PAS PF00989.25 CEP19380.1 - 3.5e-11 43.1 0.0 3.4e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 CEP19380.1 - 1.2e-08 35.1 0.0 0.00041 20.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 CEP19380.1 - 1.2e-07 31.9 0.0 5.9e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 CEP19380.1 - 0.019 15.0 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 PAS domain F-box-like PF12937.7 CEP19381.1 - 7e-10 38.7 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2722 PF10846.8 CEP19381.1 - 0.00016 20.8 17.2 0.00016 20.8 17.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) FHIPEP PF00771.20 CEP19381.1 - 0.0036 15.9 1.1 0.0055 15.2 1.1 1.2 1 0 0 1 1 1 1 FHIPEP family Suf PF05843.14 CEP19381.1 - 0.0043 17.1 3.3 0.0043 17.1 3.3 2.1 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TFIIA PF03153.13 CEP19381.1 - 0.0047 17.0 18.4 0.0047 17.0 18.4 2.5 3 0 0 3 3 2 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CEP19381.1 - 0.0049 17.5 5.7 0.0049 17.5 5.7 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CEP19381.1 - 0.0071 15.2 1.0 0.0071 15.2 1.0 1.5 2 0 0 2 2 1 1 Presenilin DDHD PF02862.17 CEP19381.1 - 0.0091 16.2 0.7 0.0091 16.2 0.7 1.8 2 0 0 2 2 2 1 DDHD domain DUF4834 PF16118.5 CEP19381.1 - 0.011 16.7 7.0 0.011 16.7 7.0 2.5 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 CEP19381.1 - 0.013 15.3 0.6 0.027 14.2 0.6 1.5 1 0 0 1 1 1 0 Connexin DUF775 PF05603.12 CEP19381.1 - 0.013 15.0 4.7 0.03 13.8 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ctr PF04145.15 CEP19381.1 - 0.03 14.9 0.9 0.069 13.8 0.1 2.0 2 0 0 2 2 1 0 Ctr copper transporter family F-box PF00646.33 CEP19381.1 - 0.046 13.6 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 0 F-box domain Peptidase_S15 PF02129.18 CEP19381.1 - 0.09 12.3 6.9 0.068 12.8 3.1 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) ABC2_membrane_2 PF12679.7 CEP19381.1 - 0.093 12.0 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MecA PF05389.12 CEP19381.1 - 0.12 12.0 5.6 0.03 14.0 2.1 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Ureide_permease PF07168.11 CEP19381.1 - 0.23 10.2 0.7 0.37 9.5 0.7 1.2 1 0 0 1 1 1 0 Ureide permease DUF3408 PF11888.8 CEP19381.1 - 0.23 11.6 11.0 1.5 9.0 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) SID-1_RNA_chan PF13965.6 CEP19381.1 - 0.25 9.7 0.9 0.38 9.1 0.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DivIC PF04977.15 CEP19381.1 - 0.27 11.0 18.4 0.59 9.9 18.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Neur_chan_memb PF02932.16 CEP19381.1 - 0.3 11.1 2.2 0.63 10.1 0.8 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 CEP19381.1 - 0.31 10.8 6.2 0.13 12.1 1.6 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain ANAPC8 PF04049.13 CEP19381.1 - 0.47 10.5 6.4 0.089 12.8 2.1 1.9 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 EOS1 PF12326.8 CEP19381.1 - 0.56 10.1 2.3 0.51 10.2 0.7 1.8 2 0 0 2 2 1 0 N-glycosylation protein EIIBC-GUT_N PF03612.14 CEP19381.1 - 0.64 9.7 6.0 1.6 8.5 6.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RskA PF10099.9 CEP19381.1 - 0.67 10.2 6.0 1.4 9.2 6.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Androgen_recep PF02166.16 CEP19381.1 - 0.68 8.7 24.3 1.1 8.0 24.3 1.3 1 0 0 1 1 1 0 Androgen receptor CPSF100_C PF13299.6 CEP19381.1 - 0.69 10.1 6.3 0.14 12.3 2.1 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 CEP19381.1 - 1.4 8.7 7.8 4 7.2 7.8 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4175 PF13779.6 CEP19381.1 - 1.6 6.5 22.7 3 5.6 22.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLN3 PF02487.17 CEP19381.1 - 1.6 7.7 4.1 3 6.8 4.1 1.3 1 0 0 1 1 1 0 CLN3 protein AIF_C PF14721.6 CEP19381.1 - 2.3 8.6 6.6 1 9.7 3.8 1.8 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MctB PF11382.8 CEP19381.1 - 2.8 7.6 10.1 4.6 6.9 10.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB RBM39linker PF15519.6 CEP19381.1 - 3.1 8.9 12.4 5.2 8.2 5.7 2.5 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein SUIM_assoc PF16619.5 CEP19381.1 - 4.2 7.5 35.4 8.2e+03 -3.0 0.5 3.4 2 1 0 2 2 0 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CEP19381.1 - 4.5 6.8 42.0 0.048 13.3 32.4 2.3 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.10 CEP19381.1 - 5.3 5.6 26.9 10 4.7 26.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM51 PF15345.6 CEP19381.1 - 5.4 6.8 11.4 12 5.6 11.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4407 PF14362.6 CEP19381.1 - 5.5 6.3 16.9 10 5.4 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ORC_WH_C PF18137.1 CEP19381.1 - 5.8 7.0 10.0 15 5.7 10.0 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal ATP-synt_E PF05680.12 CEP19381.1 - 6.2 7.2 8.8 0.23 11.8 2.4 2.0 2 0 0 2 2 1 0 ATP synthase E chain Ketoacyl-synt_2 PF13723.6 CEP19381.1 - 6.6 6.3 11.9 4.1 7.0 7.1 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DUF4048 PF13257.6 CEP19381.1 - 8.8 6.1 16.0 1.4 8.7 11.9 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4048) TERB2 PF15101.6 CEP19381.1 - 8.8 6.3 21.6 3.2 7.8 13.6 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 HABP4_PAI-RBP1 PF04774.15 CEP19382.1 - 0.0099 16.7 9.2 0.0099 16.7 9.2 3.8 4 1 0 4 4 4 1 Hyaluronan / mRNA binding family SKG6 PF08693.10 CEP19384.1 - 0.0064 15.9 3.4 0.014 14.8 3.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Romo1 PF10247.9 CEP19384.1 - 0.12 12.8 0.4 0.27 11.6 0.4 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 BTB_2 PF02214.22 CEP19385.1 - 9.6e-19 67.5 0.0 2.5e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain CNH PF00780.22 CEP19386.1 - 2.8e-39 135.4 0.0 8.7e-33 114.1 0.0 2.4 2 0 0 2 2 2 2 CNH domain RhoGEF PF00621.20 CEP19386.1 - 2.5e-35 122.4 3.6 3.8e-35 121.8 2.8 1.8 1 1 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP19386.1 - 7.7e-18 64.9 0.0 2.3e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 CEP19386.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 PH domain DEP PF00610.21 CEP19386.1 - 0.026 14.6 0.0 0.092 12.8 0.0 2.0 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 CEP19386.1 - 0.044 13.6 0.5 0.32 10.8 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain DUF4203 PF13886.6 CEP19387.1 - 2.9e-22 79.3 26.2 4.5e-22 78.7 26.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) PsbH PF00737.20 CEP19387.1 - 0.0036 17.0 0.1 0.0036 17.0 0.1 2.9 5 0 0 5 5 5 1 Photosystem II 10 kDa phosphoprotein DUF872 PF05915.12 CEP19387.1 - 1 9.6 0.0 1 9.6 0.0 3.4 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) KCNQ2_u3 PF16642.5 CEP19388.1 - 0.00071 20.5 2.0 0.0012 19.8 2.0 1.3 1 0 0 1 1 1 1 Unstructured region on Potassium channel subunit alpha KvLQT2 Pkinase PF00069.25 CEP19389.1 - 5.4e-66 222.7 0.0 1.1e-65 221.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19389.1 - 1.1e-44 152.7 0.0 2.5e-44 151.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CEP19389.1 - 2.3e-05 23.9 0.1 4.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CEP19389.1 - 0.00013 21.4 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CEP19389.1 - 0.023 14.6 0.3 7.6 6.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP19389.1 - 0.11 11.5 0.0 0.11 11.5 0.0 2.5 2 0 0 2 2 2 0 Haspin like kinase domain Ank_2 PF12796.7 CEP19390.1 - 9.1e-29 99.9 0.0 2.2e-11 44.2 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP19390.1 - 2.1e-19 69.6 2.7 4.6e-07 30.3 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP19390.1 - 3.8e-18 63.7 0.0 1.4e-05 25.1 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CEP19390.1 - 1.6e-14 53.6 0.1 0.0043 17.4 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CEP19390.1 - 4.5e-10 39.6 0.1 0.00071 19.8 0.0 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DBINO PF13892.6 CEP19390.1 - 0.33 11.3 7.7 0.098 13.0 3.7 2.2 2 1 1 3 3 3 0 DNA-binding domain POX PF07526.11 CEP19390.1 - 2.6 8.6 6.9 0.27 11.8 1.4 2.2 2 0 0 2 2 2 0 Associated with HOX Zn_clus PF00172.18 CEP19391.1 - 0.00071 19.6 9.0 0.0013 18.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3770 PF12603.8 CEP19391.1 - 0.034 13.7 3.0 0.084 12.4 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) STE PF02200.16 CEP19392.1 - 4.3e-55 184.8 0.1 8.9e-55 183.8 0.1 1.6 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 CEP19392.1 - 9.5e-11 41.5 10.2 1.1e-05 25.6 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP19392.1 - 2.4e-07 30.9 2.9 2.4e-07 30.9 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP19392.1 - 2.6e-07 30.9 8.1 0.0021 18.8 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CEP19392.1 - 0.00099 19.0 1.5 0.00099 19.0 1.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP19392.1 - 0.0041 17.4 3.4 0.31 11.4 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Chal_sti_synt_C PF02797.15 CEP19392.1 - 0.046 13.7 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain zf-C2HE PF16278.5 CEP19392.1 - 2.2 8.8 7.8 0.93 10.0 3.7 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CEP19392.1 - 2.6 8.6 4.8 3.7 8.1 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Sterol_MT_C PF08498.10 CEP19393.1 - 9.3e-29 99.5 1.6 1.6e-28 98.8 1.6 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CEP19393.1 - 1.5e-21 76.8 0.0 4.9e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP19393.1 - 3e-19 69.5 0.0 7.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP19393.1 - 3.5e-18 65.9 0.0 5.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP19393.1 - 1e-11 44.7 0.1 1.5e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CEP19393.1 - 1.6e-11 44.0 0.0 2.6e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CEP19393.1 - 3.1e-11 43.4 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CEP19393.1 - 4.5e-11 43.4 0.0 1.3e-10 41.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CEP19393.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 CEP19393.1 - 0.045 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 CEP19393.1 - 0.057 13.2 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CEP19393.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 CEP19393.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PITH PF06201.13 CEP19394.1 - 1.5e-44 151.9 0.2 1.9e-44 151.6 0.2 1.1 1 0 0 1 1 1 1 PITH domain Nuc_sug_transp PF04142.15 CEP19395.1 - 6.4e-114 380.4 16.2 7.2e-114 380.2 16.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CEP19395.1 - 3.4e-07 30.5 25.2 7.5e-05 22.9 3.3 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CEP19395.1 - 0.047 12.9 19.8 0.066 12.4 4.0 2.7 1 1 1 2 2 2 0 UAA transporter family Rpr2 PF04032.16 CEP19397.1 - 8.4e-17 61.3 2.9 8.4e-17 61.3 2.9 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4461 PF14688.6 CEP19397.1 - 0.015 15.1 0.3 0.023 14.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) CENP-B_N PF04218.13 CEP19397.1 - 0.019 14.6 0.9 0.066 12.9 0.9 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Topoisom_I_N PF02919.15 CEP19397.1 - 0.66 9.4 6.9 0.23 10.9 2.0 2.0 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment HMG_box PF00505.19 CEP19398.1 - 3.5e-16 59.4 0.9 1.4e-15 57.4 0.9 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CEP19398.1 - 1.3e-10 41.7 0.5 1.3e-10 41.7 0.5 3.4 3 1 1 4 4 4 1 HMG-box domain SAM_2 PF07647.17 CEP19398.1 - 0.00028 20.9 1.0 0.00044 20.3 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CEP19398.1 - 0.00041 20.7 0.8 0.0027 18.1 0.2 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 CEP19398.1 - 0.0093 16.0 0.2 0.023 14.7 0.2 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) WYL_3 PF18488.1 CEP19398.1 - 0.14 12.6 1.0 0.3 11.5 1.0 1.5 1 0 0 1 1 1 0 WYL domain OATP PF03137.20 CEP19398.1 - 3.7 5.7 4.8 6.9 4.8 4.8 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM163 PF15069.6 CEP19398.1 - 5.6 7.4 8.4 22 5.5 0.2 2.9 2 0 0 2 2 2 0 FAM163 family zf-C2H2 PF00096.26 CEP19399.1 - 7.1e-07 29.3 2.3 7.1e-07 29.3 2.3 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP19399.1 - 0.0018 18.9 1.9 0.0046 17.7 1.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger Ogr_Delta PF04606.12 CEP19399.1 - 0.06 13.3 2.0 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.6 CEP19399.1 - 0.087 13.3 7.6 2.6 8.6 2.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DUF1358 PF07096.11 CEP19400.1 - 5.7e-08 32.7 0.1 1.2e-07 31.6 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1358) Gram_pos_anchor PF00746.21 CEP19400.1 - 0.46 10.5 4.1 4 7.5 0.2 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Hydrolase_6 PF13344.6 CEP19401.1 - 3.9e-26 91.1 0.0 6.3e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP19401.1 - 5.4e-16 58.4 0.0 1.5e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP19401.1 - 4.7e-05 23.8 0.1 0.0016 18.8 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CEP19401.1 - 0.00019 21.6 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 CEP19401.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF4476 PF14771.6 CEP19402.1 - 0.018 15.3 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) DUF2618 PF10940.8 CEP19403.1 - 0.02 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) HD_3 PF13023.6 CEP19405.1 - 0.0025 17.7 1.1 0.11 12.4 0.0 2.4 1 1 0 2 2 2 2 HD domain DUF4482 PF14818.6 CEP19405.1 - 0.045 14.6 2.1 0.17 12.8 2.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) VTC PF09359.10 CEP19406.1 - 4.5e-84 282.1 0.0 1e-83 280.9 0.0 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CEP19406.1 - 1.1e-13 51.4 3.0 2.3e-13 50.3 3.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP19406.1 - 3.9e-12 46.8 13.9 4.6e-06 26.8 0.9 4.2 2 1 2 4 4 4 3 SPX domain Arm PF00514.23 CEP19406.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat VTC PF09359.10 CEP19407.1 - 2e-49 168.5 0.1 7.7e-49 166.5 0.1 2.1 1 1 0 1 1 1 1 VTC domain DUF202 PF02656.15 CEP19407.1 - 1.3e-13 51.1 1.9 3e-13 50.0 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP19407.1 - 5.4e-11 43.0 16.9 1.4e-06 28.5 0.7 3.3 2 1 2 4 4 4 2 SPX domain VTC PF09359.10 CEP19408.1 - 1.4e-83 280.5 0.5 1.4e-83 280.5 0.5 2.2 3 0 0 3 3 3 1 VTC domain DUF202 PF02656.15 CEP19408.1 - 7.1e-12 45.6 4.7 7.5e-12 45.5 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CEP19408.1 - 1.3e-07 31.9 18.9 3.8e-06 27.1 6.0 3.4 2 1 1 3 3 3 2 SPX domain MscS_TM PF12794.7 CEP19408.1 - 0.014 14.3 2.3 0.021 13.7 2.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4064 PF13273.6 CEP19408.1 - 0.12 12.6 0.2 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3037 PF11236.8 CEP19409.1 - 0.013 15.9 0.5 0.079 13.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Dermcidin PF15291.6 CEP19409.1 - 0.096 13.2 3.5 0.47 11.0 0.3 3.3 3 0 0 3 3 3 0 Dermcidin, antibiotic peptide 6PF2K PF01591.18 CEP19410.1 - 5.8e-69 231.8 1.1 8.8e-69 231.2 1.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CEP19410.1 - 3.9e-34 118.1 0.0 6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_fiber_2 PF03406.13 CEP19410.1 - 0.18 11.4 0.1 0.45 10.1 0.1 1.7 1 0 0 1 1 1 0 Phage tail fibre repeat Fungal_trans PF04082.18 CEP19411.1 - 3.3e-21 75.5 2.6 5.9e-21 74.7 2.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CEP19411.1 - 2.2e-08 34.1 7.4 5.8e-08 32.7 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pneumo_M2 PF07380.11 CEP19411.1 - 0.04 14.2 0.5 0.15 12.3 0.5 2.1 1 0 0 1 1 1 0 Pneumovirus M2 protein E2F_TDP PF02319.20 CEP19412.1 - 8.3e-24 83.4 0.2 1.4e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain GrpE PF01025.19 CEP19412.1 - 0.066 12.9 0.3 0.094 12.4 0.3 1.2 1 0 0 1 1 1 0 GrpE PPR_2 PF13041.6 CEP19413.1 - 9.6e-63 208.2 24.1 3.4e-11 43.1 0.0 16.9 14 3 3 17 17 17 12 PPR repeat family PPR PF01535.20 CEP19413.1 - 1.7e-49 162.7 16.9 0.00062 19.8 0.0 19.8 21 1 1 22 22 20 11 PPR repeat PPR_3 PF13812.6 CEP19413.1 - 1.9e-41 140.0 19.0 1.7e-10 40.8 0.2 12.5 10 4 3 14 14 14 9 Pentatricopeptide repeat domain PPR_long PF17177.4 CEP19413.1 - 2.5e-32 112.0 18.8 9e-10 38.3 0.2 8.2 3 2 4 8 8 8 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEP19413.1 - 3.9e-19 68.1 16.1 0.34 10.6 0.0 14.6 19 0 0 19 19 18 4 PPR repeat TPR_19 PF14559.6 CEP19413.1 - 2e-09 37.8 6.3 0.67 10.5 0.0 7.8 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19413.1 - 1.2e-08 35.0 0.0 15 6.7 0.0 10.3 11 1 1 12 12 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 CEP19413.1 - 4.8e-05 23.2 9.3 16 5.9 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat ATP13 PF12921.7 CEP19413.1 - 9e-05 22.3 8.1 1 9.2 0.0 8.2 6 2 3 11 11 10 1 Mitochondrial ATPase expression TPR_6 PF13174.6 CEP19413.1 - 0.00029 21.3 6.5 6.9 7.5 0.0 7.8 8 0 0 8 8 6 1 Tetratricopeptide repeat RPM2 PF08579.11 CEP19413.1 - 0.0003 21.2 5.9 0.31 11.5 0.0 5.7 5 2 1 6 6 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 CEP19413.1 - 0.00057 19.7 2.7 8 6.7 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 CEP19413.1 - 0.0041 17.7 1.0 25 5.6 0.1 5.9 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19413.1 - 0.012 15.8 18.5 6.7 7.2 0.1 7.9 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 CEP19413.1 - 0.012 15.8 9.5 5.4 7.4 0.1 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat Rep_fac_C PF08542.11 CEP19413.1 - 0.055 13.9 0.3 20 5.7 0.0 4.9 5 0 0 5 5 5 0 Replication factor C C-terminal domain Vps39_1 PF10366.9 CEP19413.1 - 0.11 12.8 0.4 7 7.0 0.0 3.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 BTAD PF03704.17 CEP19413.1 - 0.13 12.7 0.9 1e+02 3.3 0.0 4.9 4 1 1 5 5 4 0 Bacterial transcriptional activator domain Mic1 PF07035.12 CEP19413.1 - 0.19 11.5 2.6 3.6 7.3 0.0 3.8 4 0 0 4 4 4 0 Colon cancer-associated protein Mic1-like TPR_15 PF13429.6 CEP19413.1 - 0.24 10.6 7.0 0.13 11.4 0.5 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19413.1 - 0.34 10.8 10.8 23 5.0 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF5344 PF17279.2 CEP19413.1 - 0.68 10.6 3.4 13 6.4 0.1 4.1 4 0 0 4 4 3 0 Family of unknown function (DUF5344) Mad3_BUB1_I PF08311.12 CEP19413.1 - 1.9 8.5 8.7 9.7 6.2 0.1 3.8 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 HOOK PF05622.12 CEP19414.1 - 2.3e-54 184.8 86.0 1.2e-49 169.1 58.3 2.5 1 1 1 2 2 2 2 HOOK protein GCK PF07802.11 CEP19414.1 - 0.0047 17.3 2.0 0.02 15.3 2.0 2.2 1 0 0 1 1 1 1 GCK domain CNH PF00780.22 CEP19415.1 - 3.4e-55 187.6 0.3 2.6e-54 184.7 0.3 2.2 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CEP19415.1 - 3.1e-36 125.3 2.1 8.2e-36 123.9 2.1 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CEP19415.1 - 2.2e-33 115.2 4.4 3.1e-33 114.7 0.0 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain DEP PF00610.21 CEP19415.1 - 5.2e-16 58.5 0.1 2.5e-15 56.3 0.1 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 CEP19415.1 - 0.03 14.1 0.2 4.1 7.2 0.2 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain FAM86 PF14904.6 CEP19415.1 - 0.043 13.9 0.0 3.4 7.8 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function HSP70 PF00012.20 CEP19416.1 - 0.0014 16.9 0.0 0.01 14.1 0.0 2.0 2 0 0 2 2 2 1 Hsp70 protein LTV PF04180.14 CEP19416.1 - 0.25 11.0 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein Proteasome PF00227.26 CEP19417.1 - 1.2e-63 214.0 0.3 1.7e-63 213.6 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CEP19417.1 - 5.8e-13 48.3 0.1 1e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_S13 PF00416.22 CEP19417.1 - 0.22 11.9 1.1 0.42 11.0 1.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DUF5069 PF16798.5 CEP19417.1 - 0.37 11.0 2.3 1.7 8.9 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5069) Pex2_Pex12 PF04757.14 CEP19419.1 - 1.2e-34 119.9 2.1 1.5e-34 119.5 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CEP19419.1 - 8.4e-09 35.2 11.6 1.4e-08 34.5 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CEP19419.1 - 1.1e-08 35.2 14.1 2e-08 34.5 14.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CEP19419.1 - 5.3e-08 32.6 13.6 9e-08 31.9 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CEP19419.1 - 1.6e-07 31.1 12.3 2.6e-07 30.4 12.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CEP19419.1 - 3.2e-07 30.1 13.9 5.4e-07 29.3 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CEP19419.1 - 5.6e-05 23.3 10.2 0.00011 22.4 10.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CEP19419.1 - 0.00044 20.1 11.0 0.00078 19.4 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CEP19419.1 - 0.00047 20.1 12.8 0.0011 18.9 12.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CEP19419.1 - 0.016 15.4 12.7 0.035 14.3 12.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PAXIP1_C PF15364.6 CEP19419.1 - 0.039 14.3 0.2 0.073 13.4 0.2 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein zf-RING_6 PF14835.6 CEP19419.1 - 0.059 13.3 4.2 0.11 12.4 4.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CEP19419.1 - 0.18 11.6 2.7 0.52 10.1 2.7 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 CEP19419.1 - 0.39 10.9 8.5 0.78 9.9 8.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CEP19419.1 - 2.4 8.3 8.6 1.9 8.6 6.6 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ytp1 PF10355.9 CEP19420.1 - 2.6e-103 345.0 11.9 6.3e-103 343.8 11.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CEP19420.1 - 1.1e-24 86.2 6.6 1.1e-24 86.2 6.6 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 CEP19420.1 - 0.015 15.4 12.9 0.015 15.4 12.9 4.8 3 2 2 5 5 5 0 Eukaryotic cytochrome b561 Tetraspanin PF00335.20 CEP19420.1 - 6.7 6.3 10.3 0.37 10.5 0.4 3.0 3 1 0 3 3 3 0 Tetraspanin family PhoLip_ATPase_C PF16212.5 CEP19421.1 - 2.2e-84 283.1 22.6 2.2e-84 283.1 22.6 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CEP19421.1 - 3.8e-24 84.2 5.6 1.3e-23 82.5 5.6 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CEP19421.1 - 5.3e-13 49.7 0.1 2.2e-08 34.6 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP19421.1 - 6.9e-11 42.1 0.0 2.8e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CEP19421.1 - 1.1e-09 38.1 0.0 3.2e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CEP19421.1 - 0.0007 19.4 0.0 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ILVD_EDD PF00920.21 CEP19422.1 - 2.7e-210 699.4 0.2 3.2e-210 699.2 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family DDE_3 PF13358.6 CEP19424.1 - 7.3e-21 74.5 0.0 5e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 CEP19424.1 - 0.0004 19.5 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain CT_C_D PF02682.16 CEP19425.1 - 0.087 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D MIR PF02815.19 CEP19426.1 - 2.3e-17 63.5 1.8 1.6e-13 50.9 0.4 3.0 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 CEP19426.1 - 6.2e-08 32.1 0.4 3.8e-05 23.0 0.0 2.0 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.6 CEP19426.1 - 0.0098 16.6 0.1 1.1 10.0 0.1 2.5 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.13 CEP19426.1 - 0.056 13.7 0.3 14 6.0 0.1 2.4 2 1 0 2 2 2 0 Fascin domain RAP1 PF07218.11 CEP19427.1 - 0.009 14.4 0.2 0.01 14.2 0.2 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) ATPase PF06745.13 CEP19427.1 - 0.017 14.4 0.5 0.018 14.4 0.5 1.1 1 0 0 1 1 1 0 KaiC RNA_pol PF00940.19 CEP19427.1 - 0.02 13.8 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase mTERF PF02536.14 CEP19427.1 - 0.026 13.5 0.4 0.028 13.3 0.4 1.1 1 0 0 1 1 1 0 mTERF DUF3450 PF11932.8 CEP19427.1 - 0.09 12.1 2.3 0.11 11.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FAR1 PF03101.15 CEP19428.1 - 1.1e-05 26.1 0.2 1.7e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain HLH PF00010.26 CEP19430.1 - 7.9e-18 64.2 0.3 7.9e-18 64.2 0.3 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cluap1 PF10234.9 CEP19430.1 - 0.027 13.9 5.9 0.05 13.0 5.9 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Gp_dh_C PF02800.20 CEP19432.1 - 0.13 11.8 1.9 0.25 10.9 1.9 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain bZIP_1 PF00170.21 CEP19433.1 - 3.5e-12 46.2 10.8 3.5e-12 46.2 10.8 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CEP19433.1 - 5e-12 45.7 7.7 5e-12 45.7 7.7 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CEP19433.1 - 0.00032 21.2 9.1 0.00057 20.3 8.5 1.8 1 1 0 1 1 1 1 bZIP Maf transcription factor DUF2353 PF09789.9 CEP19433.1 - 0.0066 15.9 6.4 0.0079 15.6 6.4 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TMCO5 PF14992.6 CEP19433.1 - 0.085 12.4 6.5 0.12 12.0 6.1 1.4 1 1 0 1 1 1 0 TMCO5 family HALZ PF02183.18 CEP19433.1 - 0.09 13.0 7.8 1.7 8.9 0.3 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.18 CEP19433.1 - 0.1 12.9 0.5 0.1 12.9 0.5 2.1 3 0 0 3 3 3 0 TSC-22/dip/bun family Fungal_TACC PF12709.7 CEP19433.1 - 0.12 12.9 4.8 0.12 12.8 1.7 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4094 PF13334.6 CEP19433.1 - 0.22 12.0 1.9 0.35 11.3 1.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) YabA PF06156.13 CEP19433.1 - 1.8 9.3 6.7 0.88 10.2 3.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA O-FucT PF10250.9 CEP19434.1 - 3.3e-14 53.3 0.6 3.9e-12 46.5 0.6 2.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.32 CEP19435.1 - 3.1e-13 50.0 1.0 0.032 15.1 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19435.1 - 0.00013 22.2 0.1 3.9 7.8 0.0 4.7 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 CEP19436.1 - 1e-44 152.4 3.1 4.7e-24 85.5 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CEP19436.1 - 2.8e-12 47.1 14.4 0.00037 20.4 2.1 5.0 3 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CEP19436.1 - 1.2e-10 41.5 0.3 0.00042 20.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CEP19436.1 - 3.2e-10 39.8 8.2 0.0022 17.5 0.2 4.0 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CEP19436.1 - 6.5e-07 29.7 0.0 0.003 17.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain ABC_tran_Xtn PF12848.7 CEP19436.1 - 1.5e-06 28.1 9.7 1.5e-06 28.1 9.7 2.3 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.6 CEP19436.1 - 6.3e-06 25.8 0.0 0.023 14.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CEP19436.1 - 7.6e-06 26.0 0.8 0.011 15.8 0.0 3.5 4 0 0 4 4 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CEP19436.1 - 8e-06 26.2 0.0 0.32 11.4 0.0 3.2 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.12 CEP19436.1 - 1.1e-05 25.4 0.0 0.054 13.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 CEP19436.1 - 2.3e-05 24.8 0.0 0.2 12.1 0.0 3.5 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CEP19436.1 - 7.9e-05 22.5 18.6 0.00086 19.1 0.0 4.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 CEP19436.1 - 0.0001 22.5 5.0 0.61 10.2 0.9 4.2 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.6 CEP19436.1 - 0.00013 22.4 0.1 0.51 10.7 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CEP19436.1 - 0.00015 21.8 0.1 5.6 7.0 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 CEP19436.1 - 0.00061 20.1 0.0 0.0093 16.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CEP19436.1 - 0.00098 18.9 0.0 2.2 8.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CEP19436.1 - 0.0011 19.6 0.1 0.082 13.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.9 CEP19436.1 - 0.0012 18.1 8.7 0.0048 16.1 0.1 3.6 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 CEP19436.1 - 0.0041 16.7 0.0 2.5 7.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Rad17 PF03215.15 CEP19436.1 - 0.0045 16.9 0.0 0.45 10.4 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain FeoB_N PF02421.18 CEP19436.1 - 0.0046 16.5 2.7 0.078 12.5 0.1 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_5 PF07728.14 CEP19436.1 - 0.007 16.4 0.1 4 7.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CEP19436.1 - 0.0075 15.5 1.1 1.4 8.0 0.0 3.0 4 0 0 4 4 3 1 NB-ARC domain Roc PF08477.13 CEP19436.1 - 0.0084 16.3 0.1 5.5 7.2 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CEP19436.1 - 0.017 15.6 0.0 0.017 15.6 0.0 4.3 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.6 CEP19436.1 - 0.018 14.6 0.0 5 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CEP19436.1 - 0.061 13.1 0.1 20 4.9 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 CEP19436.1 - 0.095 12.6 0.0 19 5.1 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 CEP19436.1 - 0.11 12.2 0.2 1.4 8.7 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CEP19436.1 - 0.12 12.5 0.0 0.12 12.5 0.0 3.4 3 1 1 4 4 4 0 Dynamin family KapB PF08810.10 CEP19436.1 - 0.29 11.3 2.2 0.85 9.8 0.1 2.8 3 0 0 3 3 3 0 Kinase associated protein B ABC2_membrane PF01061.24 CEP19437.1 - 6e-84 280.7 53.1 3.9e-46 157.1 17.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CEP19437.1 - 2.1e-37 128.7 0.0 8.1e-20 71.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CEP19437.1 - 3e-33 113.6 1.8 4e-25 87.5 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CEP19437.1 - 1.5e-15 57.6 0.1 3.9e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CEP19437.1 - 3.8e-07 29.5 44.7 0.00095 18.4 12.7 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 CEP19437.1 - 0.0001 22.8 0.0 0.079 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CEP19437.1 - 0.00013 21.8 0.1 0.35 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CEP19437.1 - 0.00014 21.6 1.1 0.023 14.4 0.2 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CEP19437.1 - 0.00014 21.8 0.2 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CEP19437.1 - 0.0012 19.3 0.1 0.054 14.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CEP19437.1 - 0.0028 17.7 0.2 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 CEP19437.1 - 0.017 14.7 0.1 0.048 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEP19437.1 - 0.024 14.9 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CEP19437.1 - 0.061 13.0 0.3 3.5 7.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain Pax2_C PF12403.8 CEP19437.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Paired-box protein 2 C terminal AAA_23 PF13476.6 CEP19437.1 - 0.72 10.3 0.0 0.72 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain FUSC_2 PF13515.6 CEP19438.1 - 1.5e-14 54.2 13.6 1.5e-14 54.2 13.6 3.8 3 1 1 4 4 4 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CEP19438.1 - 1.5e-13 51.2 0.0 2.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC PF04632.12 CEP19438.1 - 1.4e-07 30.5 5.2 1.4e-07 30.5 5.2 2.4 2 1 1 3 3 3 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 CEP19438.1 - 2.2e-06 27.0 15.7 3.5e-06 26.3 1.8 2.5 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 CEP19438.1 - 5.2e-05 22.3 4.7 5.2e-05 22.3 4.7 2.5 3 0 0 3 3 3 2 Aluminium activated malate transporter AMP-binding PF00501.28 CEP19439.1 - 1.2e-98 330.5 0.0 1.9e-98 329.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP19439.1 - 1e-14 55.2 0.1 2.3e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CEP19440.1 - 8.8e-91 304.6 0.0 1.1e-90 304.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CEP19440.1 - 1.2e-11 45.4 0.0 2.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.20 CEP19441.1 - 5.8e-50 169.3 3.8 2.5e-49 167.3 0.0 3.4 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CEP19441.1 - 4.2e-15 56.6 0.4 1.9e-14 54.4 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP19441.1 - 1.7e-12 46.8 0.0 4.8e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP19441.1 - 6.7e-05 22.7 0.2 6.7e-05 22.7 0.2 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CEP19441.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) SWIRM PF04433.17 CEP19442.1 - 1e-21 77.0 0.1 1.5e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 CEP19442.1 - 6.6e-14 51.8 0.5 6.6e-14 51.8 0.5 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain JAB PF01398.21 CEP19442.1 - 2.3e-10 40.5 0.0 5.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CEP19442.1 - 6.2e-09 35.7 0.1 1.3e-07 31.4 0.0 2.3 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 CEP19442.1 - 8.9e-08 32.3 2.0 2.4e-07 30.9 0.3 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 CEP19442.1 - 0.00013 22.0 0.5 0.00048 20.1 0.0 2.2 2 0 0 2 2 2 1 SLIDE UPF0172 PF03665.13 CEP19442.1 - 0.079 13.0 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) NDT80_PhoG PF05224.12 CEP19443.1 - 4.3e-37 128.1 4.8 7.4e-37 127.4 0.0 2.8 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF5509 PF17625.2 CEP19443.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5509) DAHP_synth_2 PF01474.16 CEP19444.1 - 1.4e-207 689.5 0.0 1.5e-207 689.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Lipase_GDSL PF00657.22 CEP19445.1 - 3e-06 27.3 0.3 7.1e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CEP19445.1 - 3.6e-06 27.5 0.1 1.4e-05 25.6 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_16 PF10294.9 CEP19446.1 - 2.6e-31 108.7 0.0 3.7e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CEP19446.1 - 0.00016 21.6 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CEP19446.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 CEP19446.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CEP19446.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SAICAR_synt PF01259.18 CEP19448.1 - 6.6e-105 350.3 0.1 8e-105 350.0 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase zf-C2H2 PF00096.26 CEP19449.1 - 5.7e-14 51.7 14.8 6.4e-06 26.3 3.1 4.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP19449.1 - 2.8e-08 33.9 14.7 0.0072 17.1 2.1 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CEP19449.1 - 1.2e-07 31.8 10.2 0.0037 17.6 0.4 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-LYAR PF08790.11 CEP19449.1 - 0.043 13.7 7.5 5.1 7.1 0.4 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 CEP19449.1 - 0.14 12.2 6.0 0.14 12.1 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4710 PF15828.5 CEP19449.1 - 0.53 10.4 4.1 1.3 9.2 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) zf-met PF12874.7 CEP19449.1 - 1.7 9.1 7.3 4.8 7.7 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type POPLD PF08170.12 CEP19449.1 - 2 8.8 6.2 0.99 9.8 3.0 2.2 2 0 0 2 2 2 0 POPLD (NUC188) domain RRN3 PF05327.11 CEP19450.1 - 6.7e-172 572.9 10.0 6.7e-172 572.9 10.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CBF PF03914.17 CEP19450.1 - 0.17 11.9 1.0 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 CBF/Mak21 family SapB_2 PF03489.17 CEP19450.1 - 2.1 8.6 6.1 9.2 6.5 0.4 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 2 Pkinase PF00069.25 CEP19451.1 - 5e-50 170.3 0.0 8.9e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19451.1 - 4.8e-21 75.2 0.0 7.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19451.1 - 5.8e-05 22.6 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.7 CEP19451.1 - 0.00025 21.2 0.0 0.098 12.9 0.0 3.3 3 0 0 3 3 3 1 PAS domain Pkinase_fungal PF17667.1 CEP19451.1 - 0.00043 19.2 0.0 0.00069 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CEP19451.1 - 0.001 19.1 0.4 0.024 14.6 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CEP19451.1 - 0.0079 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 CEP19452.1 - 4.2e-08 33.4 0.8 0.44 11.5 0.1 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP19452.1 - 1.8e-07 30.7 11.1 0.055 13.6 0.6 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CEP19452.1 - 2.9e-05 24.5 5.9 0.17 12.4 0.3 4.1 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CEP19452.1 - 3.6e-05 23.4 1.3 0.0097 15.6 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 CEP19452.1 - 0.0003 21.4 0.4 4.2 8.1 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19452.1 - 0.0018 18.0 9.4 0.57 10.1 1.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Urocanase_N PF17391.2 CEP19452.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Urocanase N-terminal domain TPR_12 PF13424.6 CEP19452.1 - 0.034 14.4 4.3 2.9 8.2 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CEP19452.1 - 0.33 11.1 2.9 1.1 9.4 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CEP19452.1 - 0.73 10.6 3.6 6 7.7 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat AA_kinase PF00696.28 CEP19453.1 - 3.1e-33 115.4 0.0 3.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family Sel1 PF08238.12 CEP19455.1 - 2.3e-24 85.3 20.0 3.7e-06 27.4 0.0 8.6 8 1 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 CEP19455.1 - 0.86 10.1 6.7 60 4.3 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP19455.1 - 9.1 6.6 13.4 83 3.5 6.5 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NUDIX PF00293.28 CEP19456.1 - 5.4e-11 42.6 0.0 8.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ADH_N_2 PF16884.5 CEP19457.1 - 3.8e-19 68.6 0.0 7.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CEP19457.1 - 2e-13 50.5 0.0 7.5e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP19457.1 - 0.0016 19.5 0.0 0.0077 17.3 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase La PF05383.17 CEP19458.1 - 4.7e-21 74.6 0.5 4.7e-21 74.6 0.5 1.9 2 0 0 2 2 2 1 La domain SRF-TF PF00319.18 CEP19459.1 - 1.1e-20 72.8 0.1 1.7e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FRG1 PF06229.12 CEP19460.1 - 1.3e-23 83.7 1.8 3.8e-23 82.2 0.1 2.2 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 CEP19460.1 - 0.00034 20.8 0.0 0.00073 19.7 0.0 1.6 1 0 0 1 1 1 1 Fascin domain TFIIA_gamma_C PF02751.14 CEP19460.1 - 0.035 14.3 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit TetR_C_23 PF17931.1 CEP19460.1 - 0.1 12.7 0.2 0.1 12.7 0.2 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Sec62 PF03839.16 CEP19460.1 - 6.8 6.1 7.1 1.9 7.9 0.5 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Questin_oxidase PF14027.6 CEP19461.1 - 6.2e-23 81.9 0.0 1.1e-22 81.0 0.0 1.4 1 1 0 1 1 1 1 Questin oxidase-like SWIRM PF04433.17 CEP19462.1 - 6.2e-12 45.7 0.2 6.2e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 CEP19462.1 - 2.7e-10 40.3 0.0 7.7e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 CEP19462.1 - 1.2e-08 34.7 7.9 2.2e-08 33.8 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 CEP19462.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HEAT_2 PF13646.6 CEP19463.1 - 2e-06 28.1 1.8 0.019 15.4 0.0 5.4 5 1 0 6 6 6 1 HEAT repeats Cnd1 PF12717.7 CEP19463.1 - 0.00012 22.1 8.0 0.022 14.8 0.1 5.1 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CEP19463.1 - 0.00018 21.5 0.0 0.24 11.7 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat FANCI_S2 PF14676.6 CEP19463.1 - 0.00057 20.2 4.5 0.11 12.8 0.6 3.8 3 0 0 3 3 3 1 FANCI solenoid 2 HEAT_EZ PF13513.6 CEP19463.1 - 0.001 19.5 0.0 0.079 13.5 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CEP19463.1 - 0.13 12.9 0.8 45 4.7 0.0 4.6 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Anticodon_1 PF08264.13 CEP19463.1 - 0.9 9.5 5.0 0.67 9.9 0.0 3.4 5 0 0 5 5 5 0 Anticodon-binding domain of tRNA DUF4404 PF14357.6 CEP19463.1 - 3.8 8.2 6.9 41 4.9 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_12 PF13424.6 CEP19464.1 - 1.7e-13 50.6 13.3 4.5e-05 23.7 1.0 4.3 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CEP19464.1 - 8.6e-11 41.1 6.0 0.00049 19.9 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CEP19464.1 - 3.1e-09 36.2 13.2 0.0018 18.2 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CEP19464.1 - 5.3e-09 35.9 4.2 4e-06 26.4 0.6 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 CEP19464.1 - 1.3e-08 34.3 12.1 4.7e-05 23.0 0.1 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19464.1 - 1.6e-06 28.5 10.7 0.066 14.1 0.3 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19464.1 - 1.2e-05 25.1 8.4 0.092 13.0 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP19464.1 - 6.5e-05 23.5 8.6 0.006 17.2 1.2 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 CEP19464.1 - 0.00076 19.2 4.7 0.0077 16.0 1.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 CEP19464.1 - 0.0013 19.2 5.7 0.48 11.0 0.4 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CEP19464.1 - 0.0035 17.2 11.7 0.22 11.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 CEP19464.1 - 0.0067 16.5 3.5 0.069 13.2 0.6 3.2 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CEP19464.1 - 0.014 15.0 0.0 0.014 15.0 0.0 3.3 5 0 0 5 5 5 0 TPR repeat RPN7 PF10602.9 CEP19464.1 - 0.026 14.2 0.5 0.53 10.0 0.1 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 CEP19464.1 - 9.3 7.1 6.4 76 4.3 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.21 CEP19465.1 - 9.4e-58 195.8 0.0 1.7e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CEP19465.1 - 4.9e-25 87.3 0.0 4.9e-18 64.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Peptidase_S41_N PF11918.8 CEP19465.1 - 0.37 11.0 1.7 28 4.9 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP polyprenyl_synt PF00348.17 CEP19466.1 - 5.9e-97 323.7 0.2 7.5e-97 323.4 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DIT1_PvcA PF05141.12 CEP19466.1 - 0.0087 15.6 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein CLP_protease PF00574.23 CEP19466.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Clp protease NurA PF09376.10 CEP19467.1 - 0.018 14.8 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 NurA domain NYN_YacP PF05991.11 CEP19467.1 - 0.023 14.6 0.1 0.062 13.2 0.1 1.7 2 0 0 2 2 2 0 YacP-like NYN domain TrkA_N PF02254.18 CEP19467.1 - 0.077 13.3 0.6 0.25 11.6 0.4 1.9 1 1 1 2 2 2 0 TrkA-N domain Prok-RING_1 PF14446.6 CEP19468.1 - 0.028 14.4 1.3 0.028 14.4 1.3 4.3 4 2 0 4 4 4 0 Prokaryotic RING finger family 1 zf-C4_Topoisom PF01396.19 CEP19468.1 - 0.084 12.7 6.0 1.7 8.5 0.4 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf_UBZ PF18439.1 CEP19468.1 - 0.13 11.9 5.1 3.2 7.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CEP19468.1 - 0.16 11.9 5.1 2.8 7.9 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF4611 PF15387.6 CEP19468.1 - 0.19 12.0 1.2 23 5.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-ribbon_3 PF13248.6 CEP19468.1 - 0.24 10.8 8.0 1.2 8.6 0.3 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCHC PF00098.23 CEP19468.1 - 0.31 11.2 0.3 0.31 11.2 0.3 4.8 6 0 0 6 6 6 0 Zinc knuckle zf-C2H2_10 PF16588.5 CEP19468.1 - 0.33 10.7 7.5 0.83 9.4 0.0 3.5 3 0 0 3 3 3 0 C2H2 zinc-finger zinc_ribbon_2 PF13240.6 CEP19468.1 - 0.35 10.6 9.2 1.9 8.3 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 CEP19468.1 - 0.48 10.7 5.9 0.63 10.3 0.5 3.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain PHD PF00628.29 CEP19468.1 - 0.55 10.2 11.9 7.1 6.6 0.0 4.3 4 1 0 4 4 4 0 PHD-finger zinc-ribbons_6 PF07191.12 CEP19468.1 - 1.6 8.7 14.5 2.1 8.4 3.0 3.4 2 2 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CEP19468.1 - 1.8 8.6 14.6 8.7 6.5 4.7 3.4 2 2 0 2 2 2 0 Double zinc ribbon OSCP PF00213.18 CEP19469.1 - 1.6e-43 148.8 4.7 2e-43 148.5 4.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF4510 PF14971.6 CEP19469.1 - 0.054 13.8 0.1 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Spore_YpjB PF09577.10 CEP19469.1 - 0.13 12.1 1.2 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) BRO1 PF03097.18 CEP19471.1 - 2.8e-27 95.5 1.2 3.6e-27 95.2 1.2 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 CEP19471.1 - 7.7e-05 21.9 7.7 0.0045 16.1 3.2 3.4 2 1 1 3 3 3 2 Family of unknown function (DUF5355) ENTH PF01417.20 CEP19471.1 - 0.062 13.3 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 ENTH domain RrnaAD PF00398.20 CEP19472.1 - 8.9e-47 159.4 0.0 1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CEP19472.1 - 0.00098 19.8 0.0 0.002 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP19472.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CEP19472.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 CEP19472.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CEP19472.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase TauD PF02668.16 CEP19473.1 - 1e-57 196.0 0.3 1.3e-57 195.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Porphobil_deam PF01379.20 CEP19474.1 - 2.7e-70 236.0 0.1 2.2e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CEP19474.1 - 5.6e-18 65.1 0.8 1.3e-17 63.9 0.4 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain MmoB_DmpM PF02406.17 CEP19474.1 - 0.12 12.6 0.0 22 5.3 0.0 2.9 3 0 0 3 3 3 0 MmoB/DmpM family Dynamin_M PF01031.20 CEP19475.1 - 3.7e-108 361.1 0.1 2.9e-107 358.1 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 CEP19475.1 - 1e-56 191.6 0.1 2.3e-56 190.4 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CEP19475.1 - 3e-32 110.6 3.2 3e-32 110.6 3.2 2.3 1 1 1 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEP19475.1 - 0.00016 21.7 0.1 0.0011 19.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SWI2_SNF2 PF18766.1 CEP19475.1 - 0.052 13.2 0.3 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_16 PF13191.6 CEP19475.1 - 0.099 13.0 0.0 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain F-box-like PF12937.7 CEP19476.1 - 9.8e-05 22.2 0.1 0.00031 20.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 CEP19476.1 - 0.0023 17.5 0.4 0.0075 15.8 0.4 1.8 1 0 0 1 1 1 1 F-box F-box PF00646.33 CEP19476.1 - 0.0038 17.1 0.4 0.017 15.0 0.4 2.2 1 0 0 1 1 1 1 F-box domain Clat_adaptor_s PF01217.20 CEP19476.1 - 0.097 12.6 1.0 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 Clathrin adaptor complex small chain TOM6p PF15184.6 CEP19476.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Sugar_tr PF00083.24 CEP19477.1 - 1.6e-99 333.8 29.9 8.9e-51 173.1 4.7 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP19477.1 - 1.4e-25 90.0 40.8 4.3e-18 65.4 8.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RabGAP-TBC PF00566.18 CEP19478.1 - 3.6e-56 190.2 0.2 3.6e-56 190.2 0.2 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain ComZ PF10815.8 CEP19478.1 - 0.033 14.2 0.1 0.079 13.0 0.1 1.6 1 0 0 1 1 1 0 ComZ HALZ PF02183.18 CEP19478.1 - 0.2 11.9 16.9 5.3 7.4 0.1 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 CEP19478.1 - 0.34 10.3 21.9 0.15 11.5 17.7 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 bVLRF1 PF18826.1 CEP19478.1 - 0.44 10.4 3.5 0.97 9.3 3.5 1.5 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor zf_C2H2_ZHX PF18387.1 CEP19478.1 - 1.1 9.0 3.9 5.1 6.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain CENP-F_leu_zip PF10473.9 CEP19478.1 - 2.4 8.2 28.4 0.92 9.5 21.9 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 CEP19478.1 - 7.8 6.7 22.9 0.11 12.7 7.9 3.5 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Lipase_3 PF01764.25 CEP19479.1 - 3.6e-09 36.6 0.0 6.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CEP19479.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 CEP19479.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 CEP19479.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 CEP19479.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 CEP19480.1 - 1.2e-06 28.5 10.4 1.2e-06 28.5 10.4 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 CEP19480.1 - 9.1 6.1 16.5 13 5.7 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLP_protease PF00574.23 CEP19481.1 - 8.2e-83 276.8 0.1 1e-82 276.5 0.1 1.1 1 0 0 1 1 1 1 Clp protease SpoOE-like PF09388.10 CEP19481.1 - 0.16 11.9 1.1 0.33 10.9 1.1 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein PNRC PF15365.6 CEP19481.1 - 0.2 11.5 0.2 0.38 10.6 0.2 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Iso_dh PF00180.20 CEP19482.1 - 1.7e-77 260.9 0.0 2.2e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IBN_N PF03810.19 CEP19483.1 - 1.6e-14 53.5 0.0 4.7e-13 48.9 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CEP19483.1 - 0.00023 21.2 1.3 0.00074 19.6 0.3 2.5 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 CEP19483.1 - 0.0061 16.9 1.1 0.067 13.6 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats DUF3385 PF11865.8 CEP19483.1 - 3 7.7 6.9 4 7.3 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Nse4_C PF08743.10 CEP19484.1 - 1.4e-23 83.0 2.5 1.8e-23 82.6 0.4 2.3 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CEP19484.1 - 0.00035 20.6 0.0 0.00065 19.7 0.0 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ABC1 PF03109.16 CEP19485.1 - 8.7e-34 116.2 0.0 1.5e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family SART-1 PF03343.13 CEP19486.1 - 1.6e-135 453.2 83.0 1.5e-134 449.9 83.0 1.9 1 1 0 1 1 1 1 SART-1 family Chitin_synth_2 PF03142.15 CEP19487.1 - 2.2e-240 798.7 0.1 3.3e-240 798.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CEP19487.1 - 1e-117 394.2 0.1 1.4e-117 393.6 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 CEP19487.1 - 2.2e-19 69.1 1.4 1e-18 67.0 0.1 3.0 3 0 0 3 3 3 1 DEK C terminal domain Cyt-b5 PF00173.28 CEP19487.1 - 1.7e-18 66.5 0.4 2.4e-13 50.0 0.0 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CEP19487.1 - 1.8e-11 44.3 0.9 5.6e-11 42.7 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP19487.1 - 1.8e-10 41.1 0.0 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CEP19487.1 - 0.00014 21.7 0.3 0.013 15.3 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 2 AAA_16 PF13191.6 CEP19487.1 - 0.0025 18.2 0.3 0.0062 16.9 0.3 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CEP19487.1 - 0.026 14.3 0.0 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_transf_21 PF13506.6 CEP19487.1 - 0.11 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Cadherin_tail PF15974.5 CEP19487.1 - 0.17 12.2 0.0 0.49 10.7 0.0 1.8 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Flu_B_M2 PF04772.12 CEP19488.1 - 0.034 14.4 0.7 0.046 14.0 0.7 1.2 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) KAR9 PF08580.10 CEP19489.1 - 3.6e-09 35.8 42.2 0.00014 20.6 10.4 3.6 1 1 1 2 2 2 2 Yeast cortical protein KAR9 GAS2 PF02187.17 CEP19489.1 - 7.4e-06 26.0 0.1 0.00011 22.2 0.1 2.6 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain Perilipin PF03036.16 CEP19489.1 - 0.012 14.6 7.8 0.43 9.6 1.3 2.4 2 0 0 2 2 2 0 Perilipin family HALZ PF02183.18 CEP19489.1 - 0.033 14.4 0.2 0.13 12.5 0.2 2.1 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spectrin PF00435.21 CEP19489.1 - 0.051 14.1 9.1 2.6 8.6 1.6 3.4 3 0 0 3 3 3 0 Spectrin repeat DUF4164 PF13747.6 CEP19489.1 - 0.11 12.8 2.3 24 5.3 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) KfrA_N PF11740.8 CEP19489.1 - 0.13 13.0 0.3 0.37 11.5 0.3 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term SMP PF04927.12 CEP19490.1 - 0.083 13.4 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Seed maturation protein SIR2 PF02146.17 CEP19491.1 - 1.6e-62 210.6 0.0 2.6e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CEP19491.1 - 0.0031 17.3 0.2 0.0072 16.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) p450 PF00067.22 CEP19492.1 - 6.3e-79 265.9 0.0 7.3e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHD5 PF04420.14 CEP19493.1 - 7.6e-57 191.6 3.6 9e-57 191.4 3.6 1.0 1 0 0 1 1 1 1 CHD5-like protein ColG_sub PF18496.1 CEP19493.1 - 0.11 12.7 0.3 0.16 12.1 0.3 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Exonuc_VII_L PF02601.15 CEP19494.1 - 0.12 11.9 6.4 0.17 11.4 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1796 PF08795.10 CEP19494.1 - 0.98 9.4 9.0 41 4.1 9.0 2.7 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) UPF0242 PF06785.11 CEP19494.1 - 1.5 8.9 19.2 0.44 10.6 15.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAD-oxidase_C PF02913.19 CEP19495.1 - 1.7e-59 201.5 0.0 2.4e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CEP19495.1 - 4.6e-37 126.9 0.5 8.5e-37 126.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_20 PF00982.21 CEP19496.1 - 1.5e-162 541.6 0.0 2e-162 541.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CEP19496.1 - 3.2e-74 249.0 0.0 2.2e-72 242.9 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase S6PP PF05116.13 CEP19496.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Chitin_synth_2 PF03142.15 CEP19497.1 - 6.7e-276 916.0 2.4 9.4e-276 915.5 2.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CEP19497.1 - 3.8e-12 46.6 0.0 4.6e-11 43.0 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CEP19497.1 - 5.2e-12 46.1 3.7 2.3e-11 44.0 3.7 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CEP19497.1 - 0.00097 19.0 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CEP19497.1 - 0.0014 18.1 0.1 0.24 10.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 CEP19497.1 - 0.0052 16.9 0.0 3.1 8.0 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain HAD PF12710.7 CEP19498.1 - 1e-16 61.9 0.0 2.5e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CEP19498.1 - 2.6e-14 54.0 0.3 4.9e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CEP19498.1 - 1.2e-09 38.3 1.7 7e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 CEP19498.1 - 2.6e-08 33.7 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 ACT domain SPX PF03105.19 CEP19498.1 - 7.1e-06 26.2 3.7 0.0024 17.9 0.0 3.1 1 1 1 2 2 2 2 SPX domain Put_Phosphatase PF06888.12 CEP19498.1 - 0.0011 18.4 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.12 CEP19498.1 - 0.053 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF705) HAD_2 PF13419.6 CEP19498.1 - 0.075 13.1 0.3 8.8 6.4 0.1 3.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4806 PF16064.5 CEP19498.1 - 0.12 12.7 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DUF2710 PF10921.8 CEP19498.1 - 0.16 12.4 0.2 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2710) SelR PF01641.18 CEP19499.1 - 3e-52 175.8 0.5 3.4e-52 175.6 0.5 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CEP19499.1 - 0.0054 16.4 0.5 0.1 12.3 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 CEP19499.1 - 0.021 15.0 1.5 0.058 13.6 1.5 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CEP19499.1 - 0.022 15.0 0.2 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I ASH PF15780.5 CEP19501.1 - 4.8e-12 45.9 10.6 0.0038 17.4 0.1 8.1 9 0 0 9 9 9 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CEP19501.1 - 9e-09 35.5 7.6 1.1 9.6 0.0 7.1 5 1 2 7 7 7 3 Transmembrane protein 131-like PapD-like PF14874.6 CEP19501.1 - 5.4e-08 32.9 0.0 0.16 12.2 0.0 4.5 5 0 0 5 5 5 3 Flagellar-associated PapD-like DUF1573 PF07610.11 CEP19501.1 - 4.6e-05 23.4 4.6 2.1 8.4 0.0 5.9 6 0 0 6 6 6 3 Protein of unknown function (DUF1573) SUKH_6 PF14568.6 CEP19501.1 - 0.091 13.2 0.2 0.35 11.3 0.2 2.1 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall UBN_AB PF14075.6 CEP19501.1 - 0.21 11.3 7.3 0.56 9.9 7.3 1.7 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Polysacc_deac_1 PF01522.21 CEP19502.1 - 2.1e-21 76.1 0.0 4.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fox-1_C PF12414.8 CEP19503.1 - 0.026 14.9 0.0 0.028 14.8 0.0 1.1 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal p450 PF00067.22 CEP19504.1 - 1.9e-78 264.3 0.0 2.8e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 CEP19505.1 - 9.6e-11 41.0 0.1 1.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-GRF PF06839.12 CEP19505.1 - 1.3e-05 25.1 7.9 2.6e-05 24.2 7.9 1.5 1 0 0 1 1 1 1 GRF zinc finger ResIII PF04851.15 CEP19505.1 - 0.052 13.5 2.3 0.053 13.5 0.1 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PBECR2 PF18810.1 CEP19505.1 - 0.098 13.0 0.0 0.35 11.2 0.0 2.0 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 Nop PF01798.18 CEP19505.1 - 0.26 10.7 5.4 0.58 9.6 5.4 1.6 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin RdRP PF05183.12 CEP19506.1 - 5.9e-118 395.1 0.0 7.6e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 CEP19506.1 - 0.076 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Sporozoite_P67 PF05642.11 CEP19506.1 - 0.74 7.8 4.0 1.1 7.2 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 CEP19506.1 - 1.3 8.8 4.9 2.3 7.9 4.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spt5_N PF11942.8 CEP19506.1 - 3.2 8.8 12.1 7.8 7.5 12.1 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Tropomyosin_1 PF12718.7 CEP19507.1 - 0.0011 19.1 25.4 0.065 13.4 1.1 3.3 2 1 1 3 3 3 2 Tropomyosin like Snapin_Pallidin PF14712.6 CEP19507.1 - 0.0084 16.5 18.9 0.72 10.3 0.5 3.4 3 0 0 3 3 3 2 Snapin/Pallidin LOH1CR12 PF10158.9 CEP19507.1 - 0.011 15.8 2.5 0.011 15.8 2.5 2.8 2 1 1 3 3 3 0 Tumour suppressor protein NPV_P10 PF05531.12 CEP19507.1 - 0.052 14.0 8.2 1.1 9.8 0.2 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fer4_24 PF18109.1 CEP19507.1 - 0.13 12.5 3.3 15 5.9 0.1 3.5 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain DUF1664 PF07889.12 CEP19507.1 - 0.18 11.8 20.4 0.075 13.1 5.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CEP19507.1 - 0.2 12.3 12.4 0.26 11.9 0.2 4.0 3 1 0 3 3 3 0 SlyX Tropomyosin PF00261.20 CEP19507.1 - 0.21 10.9 25.9 0.89 8.9 0.4 3.5 1 1 1 3 3 3 0 Tropomyosin HPPK PF01288.20 CEP19507.1 - 0.25 11.8 0.2 0.25 11.8 0.2 2.8 3 1 0 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF1465 PF07323.12 CEP19507.1 - 0.32 10.8 12.8 0.45 10.3 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) Seryl_tRNA_N PF02403.22 CEP19507.1 - 0.35 11.1 24.1 2.5 8.4 3.7 3.6 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Uso1_p115_C PF04871.13 CEP19507.1 - 0.4 11.0 20.4 2.5 8.5 3.7 3.3 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region MerR-DNA-bind PF09278.11 CEP19507.1 - 0.63 10.6 2.9 11 6.6 0.0 3.4 2 2 1 3 3 3 0 MerR, DNA binding Fib_alpha PF08702.10 CEP19507.1 - 0.9 9.7 28.4 25 5.1 6.9 3.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 CEP19507.1 - 1.2 9.4 25.4 1.7 8.9 2.6 4.6 3 1 2 5 5 5 0 Haemolysin XhlA Spc110_C PF18520.1 CEP19507.1 - 1.2 8.8 4.2 0.52 10.0 0.2 2.5 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain TMF_DNA_bd PF12329.8 CEP19507.1 - 1.4 9.0 25.2 1 9.4 4.0 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 CEP19507.1 - 1.5 9.5 21.1 1.7 9.3 3.7 3.8 2 1 1 3 3 3 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 CEP19507.1 - 2.4 8.4 17.6 0.61 10.4 1.1 4.2 3 1 0 4 4 4 0 ABC transporter C-terminal domain CLZ PF16526.5 CEP19507.1 - 2.9 8.3 17.9 3.6 8.0 2.4 4.1 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOAR PF16533.5 CEP19507.1 - 3 7.9 11.3 0.31 11.0 0.2 3.5 1 1 2 4 4 4 0 STIM1 Orai1-activating region PSI_PsaF PF02507.15 CEP19507.1 - 3.4 7.5 6.5 3.2 7.6 0.2 2.8 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III Jnk-SapK_ap_N PF09744.9 CEP19507.1 - 3.7 7.8 28.6 6.1 7.0 4.7 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 CEP19507.1 - 4 7.6 12.7 3.1 7.9 0.5 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation TMPIT PF07851.13 CEP19507.1 - 4.5 6.4 24.7 0.37 10.0 5.6 3.2 2 1 1 3 3 3 0 TMPIT-like protein TMF_TATA_bd PF12325.8 CEP19507.1 - 4.8 7.4 27.0 2.2 8.5 2.9 4.0 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding DASH_Dad2 PF08654.10 CEP19507.1 - 6.3 7.3 14.2 0.17 12.3 4.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad2 Vac_Fusion PF02346.16 CEP19507.1 - 8.6 6.1 14.3 0.93 9.2 0.4 4.2 4 1 0 4 4 3 0 Chordopoxvirus multifunctional envelope protein A27 PTR2 PF00854.21 CEP19508.1 - 8.5e-93 311.3 5.0 1.8e-92 310.2 5.0 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 CEP19508.1 - 1.1e-11 44.3 20.9 4.5e-08 32.4 10.2 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 CEP19508.1 - 0.016 13.6 3.3 0.011 14.0 1.1 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CCB1 PF12046.8 CEP19508.1 - 0.1 12.0 0.2 0.3 10.4 0.2 1.8 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2207 PF09972.9 CEP19508.1 - 0.21 10.3 7.2 1.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) PTR2 PF00854.21 CEP19509.1 - 1.9e-89 300.3 8.4 2.9e-89 299.7 8.4 1.2 1 0 0 1 1 1 1 POT family CCB1 PF12046.8 CEP19509.1 - 0.15 11.4 0.2 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B DUF2104 PF09877.9 CEP19509.1 - 2 8.7 6.1 0.54 10.6 0.2 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) PIF1 PF05970.14 CEP19510.1 - 1.1e-53 182.8 1.3 2.2e-43 148.8 0.1 3.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CEP19510.1 - 3.1e-22 79.2 0.0 5.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP19510.1 - 2.5e-10 40.9 0.0 5.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP19510.1 - 8.3e-06 26.1 0.0 2.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CEP19510.1 - 0.00025 20.2 0.0 0.00048 19.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.14 CEP19510.1 - 0.00027 19.0 0.1 0.16 9.9 0.0 2.1 2 0 0 2 2 2 2 Helicase DUF2075 PF09848.9 CEP19510.1 - 0.0017 17.7 0.0 0.0039 16.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CEP19510.1 - 0.0018 17.8 0.1 0.0049 16.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CEP19510.1 - 0.0034 16.8 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Helicase_RecD PF05127.14 CEP19510.1 - 0.007 16.2 0.3 0.04 13.8 0.3 2.2 1 1 0 1 1 1 1 Helicase IstB_IS21 PF01695.17 CEP19510.1 - 0.0074 16.0 1.1 0.87 9.3 0.0 3.0 2 1 1 3 3 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CEP19510.1 - 0.0075 16.6 0.3 0.028 14.8 0.0 2.2 2 1 0 2 2 1 1 RNA helicase AAA_16 PF13191.6 CEP19510.1 - 0.0091 16.4 0.2 0.031 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CEP19510.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD_C_2 PF13538.6 CEP19510.1 - 0.012 15.4 0.3 0.053 13.3 0.3 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 CEP19510.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CEP19510.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CEP19510.1 - 0.04 13.7 3.9 0.79 9.4 0.1 3.5 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CEP19510.1 - 0.051 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CEP19510.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CEP19510.1 - 0.063 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CEP19510.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CEP19510.1 - 0.083 12.8 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CEP19510.1 - 0.095 13.2 0.1 0.095 13.2 0.1 2.8 2 1 1 3 3 2 0 ABC transporter NB-ARC PF00931.22 CEP19510.1 - 0.14 11.3 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 CEP19510.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DDHD PF02862.17 CEP19510.1 - 4.2 7.5 12.6 11 6.2 12.8 1.5 1 1 0 1 1 1 0 DDHD domain DUF5425 PF17472.2 CEP19511.1 - 0.057 14.2 0.6 0.082 13.7 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5425) DUF2805 PF10985.8 CEP19511.1 - 0.058 13.8 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Pyr_redox_2 PF07992.14 CEP19513.1 - 1.5e-69 234.5 5.9 1.5e-69 234.5 5.9 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CEP19513.1 - 1.7e-41 140.9 0.2 5.6e-41 139.2 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CEP19513.1 - 6.1e-21 74.8 6.5 8.1e-18 64.8 1.1 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CEP19513.1 - 1.8e-13 50.6 3.4 1.7e-11 44.1 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CEP19513.1 - 1.2e-11 44.4 6.1 1.4e-08 34.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CEP19513.1 - 5.7e-11 42.1 4.8 1.6e-09 37.4 1.2 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CEP19513.1 - 3e-09 36.5 13.5 6.4e-08 32.1 1.6 4.0 3 1 1 4 4 4 2 FAD binding domain Thi4 PF01946.17 CEP19513.1 - 1.3e-08 34.3 0.8 3.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CEP19513.1 - 2.1e-08 34.2 3.5 4.4e-05 23.6 0.3 3.0 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CEP19513.1 - 1.7e-06 27.0 12.4 1.7e-05 23.7 0.7 3.9 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 CEP19513.1 - 2.9e-06 26.8 9.1 0.0064 15.8 0.5 3.3 3 1 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.21 CEP19513.1 - 6.7e-06 25.6 5.3 0.0045 16.3 1.1 3.2 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 CEP19513.1 - 0.00025 20.3 0.4 0.51 9.4 0.1 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 CEP19513.1 - 0.0061 16.5 5.0 0.036 14.0 0.4 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CEP19513.1 - 0.01 15.5 14.5 0.026 14.1 0.2 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 CEP19513.1 - 0.013 15.0 3.3 0.14 11.7 0.3 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CEP19513.1 - 0.082 13.4 0.1 5.6 7.5 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 CEP19513.1 - 0.12 12.8 2.2 6.4 7.3 0.2 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CEP19513.1 - 0.8 8.7 8.6 0.12 11.4 0.4 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HAD_2 PF13419.6 CEP19514.1 - 1.4e-08 35.1 0.0 3.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CEP19514.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CEP19514.1 - 1.3e-05 25.6 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 CEP19515.1 - 3.7e-90 302.7 0.0 4.1e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PIF1 PF05970.14 CEP19516.1 - 6.2e-76 255.9 0.2 4.3e-41 141.3 0.9 2.9 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CEP19516.1 - 5e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP19516.1 - 0.00068 20.0 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP19516.1 - 0.0036 17.7 0.0 0.0085 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CEP19516.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CEP19516.1 - 0.021 13.8 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 CEP19516.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CEP19516.1 - 0.037 13.3 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CEP19516.1 - 0.041 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 CEP19516.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Bac_DnaA PF00308.18 CEP19516.1 - 0.19 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein DUF2791 PF10923.8 CEP19516.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Arginase PF00491.21 CEP19518.1 - 6.8e-76 255.4 0.0 7.9e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family HTH_32 PF13565.6 CEP19520.1 - 0.093 13.4 0.0 0.1 13.2 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 CEP19520.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 CEP19521.1 - 2.3e-09 37.2 0.0 3.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-C3HC4_2 PF13923.6 CEP19522.1 - 0.008 16.0 0.8 0.018 14.9 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 CEP19522.1 - 0.21 12.5 1.8 0.5 11.3 1.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger LSM PF01423.22 CEP19524.1 - 2.3e-18 65.6 1.3 3e-18 65.3 1.3 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CEP19524.1 - 0.03 14.4 0.2 0.046 13.9 0.2 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain UBX PF00789.20 CEP19525.1 - 2.1e-13 50.2 0.0 4.8e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CEP19525.1 - 6.4e-07 29.1 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CEP19525.1 - 0.00012 22.2 0.0 0.00053 20.1 0.0 2.2 1 0 0 1 1 1 1 Thioredoxin-like XisH PF08814.10 CEP19525.1 - 0.06 13.5 2.0 0.089 13.0 0.1 2.2 2 0 0 2 2 2 0 XisH protein V_ATPase_I PF01496.19 CEP19525.1 - 0.3 9.0 13.2 0.5 8.2 8.8 2.1 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2175 PF09943.9 CEP19525.1 - 0.37 11.1 11.2 0.077 13.3 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3391 PF11871.8 CEP19525.1 - 0.51 10.9 8.2 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Erythro_esteras PF05139.14 CEP19525.1 - 0.61 9.8 7.1 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Erythromycin esterase GvpL_GvpF PF06386.11 CEP19525.1 - 1.1 9.1 10.4 2.4 8.0 10.4 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MAS20 PF02064.15 CEP19525.1 - 1.5 9.0 10.2 0.28 11.3 5.2 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor NPAT_C PF15712.5 CEP19525.1 - 3.9 6.0 8.5 0.086 11.5 2.1 1.3 2 0 0 2 2 2 0 NPAT C terminus AAA_23 PF13476.6 CEP19525.1 - 4.9 7.6 19.7 0.033 14.7 4.9 2.4 2 0 0 2 2 2 0 AAA domain DUF2797 PF10977.8 CEP19525.1 - 8 6.3 9.9 0.33 10.8 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) DHHA2 PF02833.14 CEP19526.1 - 2.3e-24 86.2 0.3 4e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CEP19526.1 - 2.3e-08 34.2 0.2 4.9e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 DHH family F-box-like PF12937.7 CEP19526.1 - 1.5e-06 28.0 0.1 3.9e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP19526.1 - 0.00026 20.8 0.0 0.001 18.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CEP19526.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box Ribosomal_S15 PF00312.22 CEP19527.1 - 1.9e-30 104.9 2.0 1.9e-30 104.9 2.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 DnaI_N PF07319.11 CEP19527.1 - 0.23 12.1 5.6 0.44 11.2 0.1 2.7 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus RMI1_N PF08585.12 CEP19528.1 - 4.4e-37 128.0 0.0 8.6e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 RecQ mediated genome instability protein Cyt-b5 PF00173.28 CEP19529.1 - 8.5e-23 80.3 0.2 1.5e-22 79.5 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TENA_THI-4 PF03070.16 CEP19529.1 - 1.5e-09 38.0 1.2 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Polysacc_deac_1 PF01522.21 CEP19530.1 - 4e-26 91.3 0.0 7.5e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP19530.1 - 0.078 12.2 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 zf-RVT PF13966.6 CEP19531.1 - 1.5e-05 25.6 2.1 3.8e-05 24.3 2.1 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Lactate_perm PF02652.14 CEP19532.1 - 1.4e-107 360.7 26.4 6.7e-62 209.9 11.5 2.1 2 0 0 2 2 2 2 L-lactate permease OrfB_Zn_ribbon PF07282.11 CEP19532.1 - 0.019 14.9 0.2 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Acetyltransf_2 PF00797.17 CEP19532.1 - 0.036 13.9 0.2 0.069 12.9 0.2 1.4 1 0 0 1 1 1 0 N-acetyltransferase PIF1 PF05970.14 CEP19533.1 - 8.5e-10 38.3 0.1 1e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase zf-C2H2_10 PF16588.5 CEP19534.1 - 0.0005 19.7 0.4 0.001 18.7 0.4 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger DUF4451 PF14616.6 CEP19534.1 - 0.017 15.3 0.6 0.022 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) zf-H2C2_2 PF13465.6 CEP19535.1 - 8.7e-05 22.8 7.2 8.7e-05 22.8 7.2 3.9 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 CEP19535.1 - 0.00073 19.9 21.2 0.0022 18.4 5.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP19535.1 - 0.0063 17.3 3.9 0.0063 17.3 3.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger tRNA-synt_2 PF00152.20 CEP19536.1 - 5.9e-91 304.8 0.9 6e-91 304.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CEP19536.1 - 2.6e-10 40.1 0.0 5.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_L22 PF00237.19 CEP19536.1 - 0.0029 17.8 5.3 0.045 14.0 5.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Transformer PF06495.11 CEP19537.1 - 0.11 12.6 2.5 0.23 11.6 2.4 1.5 1 1 0 1 1 1 0 Fruit fly transformer protein AAA_30 PF13604.6 CEP19538.1 - 5.1e-10 39.4 0.0 6.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 CEP19538.1 - 2.5e-09 36.8 0.1 6.4e-09 35.4 0.0 1.6 1 1 1 2 2 2 1 PIF1-like helicase AAA_19 PF13245.6 CEP19538.1 - 1.6e-05 25.3 0.4 4.8e-05 23.7 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CEP19538.1 - 0.0039 17.5 0.2 0.011 16.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP19538.1 - 0.011 16.1 0.1 0.025 15.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 CEP19538.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3482 PF11981.8 CEP19538.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) dNK PF01712.19 CEP19538.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase Pox_D3 PF04580.13 CEP19538.1 - 0.067 12.8 0.1 0.079 12.6 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein RE_MamI PF09567.10 CEP19538.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 MamI restriction endonuclease AAA PF00004.29 CEP19538.1 - 0.14 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CEP19538.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Herpes_Helicase PF02689.14 CEP19539.1 - 0.00052 18.1 0.0 0.00062 17.8 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 CEP19539.1 - 0.013 14.7 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase UvrD_C_2 PF13538.6 CEP19539.1 - 0.032 14.1 0.1 0.076 12.9 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ATP-grasp_2 PF08442.10 CEP19540.1 - 6.7e-75 251.1 0.0 1.6e-74 249.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CEP19540.1 - 9.5e-24 83.9 0.6 1.6e-23 83.2 0.6 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CEP19540.1 - 1.8e-08 34.2 0.1 4.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain NDC10_II PF16787.5 CEP19540.1 - 1.5e-05 24.2 0.0 3.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GARS_A PF01071.19 CEP19540.1 - 0.003 17.3 0.0 0.19 11.5 0.0 2.5 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TOBE_2 PF08402.10 CEP19540.1 - 0.014 15.6 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 TOBE domain Flexi_CP PF00286.20 CEP19541.1 - 0.084 12.8 0.3 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Viral coat protein Josephin PF02099.17 CEP19541.1 - 0.11 12.6 1.0 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 Josephin zf-primase PF09329.11 CEP19542.1 - 1.1e-09 37.9 1.9 2e-09 37.1 1.9 1.4 1 0 0 1 1 1 1 Primase zinc finger Cyclin_N PF00134.23 CEP19543.1 - 0.00088 19.0 0.8 0.0025 17.6 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain CLTH PF10607.9 CEP19544.1 - 3e-30 105.1 0.3 3e-30 105.1 0.3 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CEP19544.1 - 0.00066 19.6 1.2 0.00095 19.1 0.2 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Poxvirus_B22R_N PF13169.6 CEP19544.1 - 0.45 11.0 0.0 0.45 11.0 0.0 2.8 3 1 0 3 3 3 0 Poxvirus B22R protein N-terminal OmpH PF03938.14 CEP19544.1 - 0.74 10.2 14.1 2.8 8.3 9.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4404 PF14357.6 CEP19544.1 - 8.8 7.0 8.9 28 5.5 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) UCH PF00443.29 CEP19545.1 - 2e-46 158.6 0.0 2.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CEP19545.1 - 9.3e-13 47.7 0.1 3.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.6 CEP19545.1 - 1.5e-09 37.9 7.9 1.5e-07 31.4 7.9 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TBK1_ULD PF18396.1 CEP19545.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF1394 PF07159.12 CEP19545.1 - 0.046 13.0 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Nop PF01798.18 CEP19546.1 - 2.8e-74 249.5 0.0 2.8e-74 249.5 0.0 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CEP19546.1 - 7.8e-39 133.3 6.5 1e-38 132.9 1.6 2.4 2 0 0 2 2 2 1 Prp31 C terminal domain Glycos_transf_N PF04413.16 CEP19546.1 - 0.11 12.2 0.6 13 5.4 0.0 2.4 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Thioredoxin_4 PF13462.6 CEP19546.1 - 0.23 11.6 2.9 0.35 11.0 1.4 2.1 1 1 0 1 1 1 0 Thioredoxin Pyr_redox_2 PF07992.14 CEP19547.1 - 2.1e-35 122.4 0.0 5.8e-32 111.1 0.0 1.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP19547.1 - 9.5e-16 58.1 0.0 7.1e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 CEP19547.1 - 3.5e-09 37.0 1.2 6.9e-09 36.0 1.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.24 CEP19547.1 - 1.2e-07 31.6 0.0 0.26 10.8 0.0 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CEP19547.1 - 3e-05 24.0 0.5 4.1 7.4 0.0 4.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CEP19547.1 - 3.2e-05 23.3 0.1 0.00037 19.8 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CEP19547.1 - 0.00012 22.3 0.0 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CEP19547.1 - 0.00072 18.8 0.0 0.096 11.8 0.0 2.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 CEP19547.1 - 0.0027 16.8 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 CEP19547.1 - 0.015 14.1 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF1188 PF06690.11 CEP19547.1 - 0.018 14.6 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) RGS-like PF09128.11 CEP19547.1 - 0.026 14.3 0.1 0.053 13.2 0.1 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Sacchrp_dh_NADP PF03435.18 CEP19547.1 - 0.072 13.3 0.1 18 5.6 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CEP19547.1 - 0.11 12.7 0.1 6.2 7.1 0.0 2.6 2 1 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 CEP19547.1 - 0.12 11.6 0.0 13 5.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RhoGEF PF00621.20 CEP19548.1 - 1.5e-27 97.0 3.2 1.5e-27 97.0 3.2 2.0 2 0 0 2 2 2 1 RhoGEF domain Gcn1_N PF12074.8 CEP19550.1 - 8.7e-94 314.7 11.4 5.4e-92 308.8 4.4 4.8 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CEP19550.1 - 1.8e-37 124.1 31.7 0.00011 22.2 0.0 21.9 24 1 1 25 25 23 6 HEAT repeat HEAT_EZ PF13513.6 CEP19550.1 - 4e-26 91.1 50.4 0.013 16.0 0.0 21.9 17 5 5 23 23 23 8 HEAT-like repeat HEAT_2 PF13646.6 CEP19550.1 - 1.9e-25 89.1 39.1 0.0042 17.4 0.2 17.0 11 2 8 20 20 20 8 HEAT repeats Cnd1 PF12717.7 CEP19550.1 - 1.3e-17 64.3 4.1 0.012 15.6 0.1 10.2 8 4 2 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CEP19550.1 - 6e-10 39.6 0.0 1.9 9.1 0.0 7.7 6 1 1 7 7 7 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CEP19550.1 - 1.7e-09 37.6 0.2 0.011 15.3 0.0 6.6 5 2 0 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 CEP19550.1 - 1.1e-08 34.1 16.3 0.013 14.1 0.2 8.5 5 2 2 8 8 8 5 Adaptin N terminal region ParcG PF10274.9 CEP19550.1 - 3.1e-07 30.7 3.7 0.25 11.4 0.0 5.9 4 2 1 6 6 6 2 Parkin co-regulated protein MMS19_C PF12460.8 CEP19550.1 - 2.4e-06 26.9 5.9 0.83 8.7 0.0 6.2 6 2 1 7 7 7 3 RNAPII transcription regulator C-terminal Arm PF00514.23 CEP19550.1 - 0.00033 20.6 0.1 22 5.3 0.1 7.4 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 CEP19550.1 - 0.006 17.0 0.1 1.9 8.9 0.0 4.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3385 PF11865.8 CEP19550.1 - 0.0091 15.9 1.1 1.4e+02 2.3 0.0 6.9 7 1 0 7 7 7 0 Domain of unknown function (DUF3385) DRIM PF07539.12 CEP19550.1 - 0.034 12.5 2.6 1.6 6.9 0.1 4.6 5 1 0 5 5 5 0 Down-regulated in metastasis EI24 PF07264.11 CEP19550.1 - 0.051 13.8 0.0 6.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) ADSL_C PF10397.9 CEP19550.1 - 0.56 10.8 4.9 19 5.9 0.0 4.8 5 0 0 5 5 5 0 Adenylosuccinate lyase C-terminus RTP1_C1 PF10363.9 CEP19550.1 - 9.2 6.5 6.2 1.9e+02 2.3 0.1 5.4 6 1 0 6 6 5 0 Required for nuclear transport of RNA pol II C-terminus 1 MIT PF04212.18 CEP19551.1 - 1.8e-05 24.7 0.1 4.9e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1079 PF06435.11 CEP19551.1 - 0.4 10.9 3.0 0.5 10.6 0.1 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Mob1_phocein PF03637.17 CEP19552.1 - 7.7e-60 201.8 0.8 3e-59 199.8 0.8 1.8 1 1 0 1 1 1 1 Mob1/phocein family DUF1075 PF06388.11 CEP19552.1 - 0.024 14.7 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DPBB_1 PF03330.18 CEP19553.1 - 2.3e-14 53.4 0.0 3.2e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP19553.1 - 0.0057 16.5 0.7 0.022 14.6 0.1 1.9 1 1 1 2 2 2 1 Barwin family MHYT PF03707.16 CEP19555.1 - 2.6e-20 72.4 12.9 1.2e-09 38.2 0.8 4.1 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat DUF1344 PF07076.11 CEP19555.1 - 0.13 12.2 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) p450 PF00067.22 CEP19556.1 - 5.7e-77 259.4 0.0 7.7e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PSDC PF12588.8 CEP19556.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Alg6_Alg8 PF03155.15 CEP19557.1 - 6.1e-141 470.7 27.4 8.2e-141 470.3 27.4 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF5435 PF17503.2 CEP19557.1 - 0.18 11.5 0.1 0.58 9.9 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5435) DUF423 PF04241.15 CEP19557.1 - 0.65 10.2 0.1 0.65 10.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF423) FAD_binding_1 PF00667.20 CEP19558.1 - 3.2e-43 147.9 0.0 4.9e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CEP19558.1 - 9e-28 97.3 0.3 2.9e-27 95.6 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CEP19558.1 - 4.9e-15 56.1 0.0 2.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 CEP19558.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain EamA PF00892.20 CEP19559.1 - 2.1e-13 50.6 33.2 1.4e-06 28.5 16.9 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 CEP19559.1 - 0.00099 18.7 13.0 0.0017 17.9 13.0 1.4 1 1 0 1 1 1 1 Solute carrier family 35 Pho86 PF11124.8 CEP19559.1 - 1.5 8.3 4.1 0.47 9.9 0.9 1.7 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Nuc_sug_transp PF04142.15 CEP19559.1 - 5.9 6.0 12.0 29 3.7 12.0 2.0 1 1 0 1 1 1 0 Nucleotide-sugar transporter DUF155 PF02582.14 CEP19560.1 - 4.2e-19 69.3 0.0 5.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UbiA PF01040.18 CEP19561.1 - 1.6e-54 184.9 16.5 2e-54 184.5 16.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ricin_B_lectin PF00652.22 CEP19562.1 - 6.4e-11 42.6 0.9 3.1e-06 27.4 0.4 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEP19562.1 - 1.9e-10 41.3 0.0 0.00022 21.9 0.0 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like LRR_8 PF13855.6 CEP19566.1 - 3.9e-28 97.0 38.3 2e-10 40.3 2.9 4.8 2 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEP19566.1 - 1.1e-18 67.0 53.5 0.00021 21.6 2.9 7.1 3 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP19566.1 - 2.3e-10 39.6 39.2 2.1 9.2 0.1 11.6 11 1 0 11 11 11 6 Leucine Rich Repeat Mucin PF01456.17 CEP19566.1 - 0.017 15.1 13.5 0.03 14.3 13.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LRR_9 PF14580.6 CEP19566.1 - 2.2 7.7 10.7 0.95 8.9 2.3 2.9 1 1 3 4 4 4 0 Leucine-rich repeat C2 PF00168.30 CEP19567.1 - 1.6e-22 79.7 0.1 2.3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 C2 domain TPR_17 PF13431.6 CEP19567.1 - 0.092 13.2 0.4 0.27 11.7 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 CEP19568.1 - 7e-60 203.1 0.0 8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CEP19568.1 - 8.9e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CEP19568.1 - 0.0005 18.7 0.0 0.00079 18.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CEP19568.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CEP19568.1 - 0.022 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_deac_1 PF01522.21 CEP19569.1 - 6.4e-09 35.8 0.0 1.5e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase Gcd10p PF04189.13 CEP19570.1 - 4.6e-71 239.4 0.5 6.8e-71 238.8 0.5 1.2 1 0 0 1 1 1 1 Gcd10p family Cpn60_TCP1 PF00118.24 CEP19571.1 - 2.9e-159 530.8 5.5 3.3e-159 530.6 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CEP19571.1 - 0.039 13.2 0.7 3.5 6.8 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Beta_helix_2 PF18835.1 CEP19571.1 - 0.16 11.8 0.0 1.7 8.5 0.1 2.6 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase RhoGAP PF00620.27 CEP19572.1 - 3.2e-36 124.5 0.1 9.1e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CEP19572.1 - 3e-31 107.4 45.0 3e-12 46.6 6.8 5.1 5 0 0 5 5 5 4 LIM domain WRKY PF03106.15 CEP19573.1 - 0.053 13.8 1.9 0.053 13.8 1.9 1.8 2 0 0 2 2 2 0 WRKY DNA -binding domain Nucleo_P87 PF07267.11 CEP19573.1 - 0.17 10.8 0.6 0.18 10.6 0.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Amidohydro_3 PF07969.11 CEP19575.1 - 5.8e-15 55.7 0.0 2.1e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 CEP19575.1 - 4.5e-14 52.5 0.0 1.4e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_S26 PF10502.9 CEP19576.1 - 1.2e-07 31.6 0.0 0.00047 19.9 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CEP19576.1 - 1.1e-06 28.4 0.1 2.1e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like GST_N_3 PF13417.6 CEP19577.1 - 2.4e-14 53.5 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CEP19577.1 - 7.1e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP19577.1 - 0.0061 16.9 0.0 0.036 14.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Aldolase_II PF00596.21 CEP19577.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain FAR1 PF03101.15 CEP19578.1 - 0.054 14.2 0.1 0.097 13.4 0.1 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain AAA PF00004.29 CEP19579.1 - 2.9e-20 73.0 0.0 5.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 CEP19579.1 - 5.4e-20 72.2 0.0 1.3e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA_5 PF07728.14 CEP19579.1 - 1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CEP19579.1 - 6.9e-05 23.3 0.0 0.00019 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CEP19579.1 - 8e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CEP19579.1 - 0.0017 18.7 0.0 0.025 15.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CEP19579.1 - 0.0032 17.0 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CEP19579.1 - 0.0037 17.2 0.0 0.2 11.6 0.0 2.6 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 CEP19579.1 - 0.0056 17.2 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CEP19579.1 - 0.011 15.4 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CEP19579.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 CEP19579.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CEP19579.1 - 0.021 14.6 0.9 0.051 13.4 0.9 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CEP19579.1 - 0.027 14.8 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEP19579.1 - 0.033 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 CEP19579.1 - 0.058 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ATP-synt_ab PF00006.25 CEP19579.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 CEP19579.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thioredoxin PF00085.20 CEP19580.1 - 2.5e-06 27.4 0.1 5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin MFS_1 PF07690.16 CEP19581.1 - 1.7e-17 63.4 37.1 1.7e-17 63.4 37.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DDOST_48kD PF03345.14 CEP19582.1 - 1.7e-128 429.0 2.6 2.1e-128 428.7 2.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta TTD PF12148.8 CEP19582.1 - 0.013 15.4 1.3 0.026 14.4 1.3 1.4 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 AstA PF04958.12 CEP19582.1 - 0.037 12.6 0.0 0.062 11.8 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit YqfQ PF14181.6 CEP19585.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF5039 PF16442.5 CEP19586.1 - 0.034 13.7 0.2 0.066 12.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5039) Orexin_rec2 PF03827.13 CEP19586.1 - 0.095 12.7 0.0 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Orexin receptor type 2 Helitron_like_N PF14214.6 CEP19589.1 - 3.9e-27 95.7 0.1 7.3e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Cactin_mid PF10312.9 CEP19589.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin SKA2 PF16740.5 CEP19590.1 - 0.09 12.6 0.6 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DDE_3 PF13358.6 CEP19591.1 - 7.9e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.13 CEP19591.1 - 0.00014 21.4 0.0 0.00032 20.3 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.16 CEP19591.1 - 0.00019 21.1 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 CEP19591.1 - 0.0047 17.0 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain SelB-wing_2 PF09106.11 CEP19591.1 - 0.023 14.9 0.0 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix HTH_23 PF13384.6 CEP19591.1 - 0.062 13.1 0.2 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 CEP19591.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_1_7 PF13843.6 CEP19593.1 - 0.00073 18.9 0.0 0.00073 18.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Glycoamylase PF10091.9 CEP19593.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 Putative glucoamylase PDH PF02153.17 CEP19597.1 - 7.9e-16 57.8 0.0 1.1e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CEP19597.1 - 3e-05 24.5 0.0 6.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CEP19597.1 - 0.001 18.7 0.0 0.003 17.2 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 CEP19597.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PglD_N PF17836.1 CEP19597.1 - 0.0097 16.5 0.0 0.032 14.9 0.0 1.9 1 0 0 1 1 1 1 PglD N-terminal domain Shikimate_DH PF01488.20 CEP19597.1 - 0.041 13.9 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CEP19597.1 - 0.056 13.3 0.0 0.097 12.5 0.0 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TB2_DP1_HVA22 PF03134.19 CEP19598.1 - 4.1 7.4 7.4 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Glycos_transf_1 PF00534.20 CEP19599.1 - 1.7e-30 105.8 0.0 2.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CEP19599.1 - 1.4e-25 90.3 0.0 2.7e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CEP19599.1 - 1.1e-24 87.3 0.1 1.8e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CEP19599.1 - 1.7e-13 51.3 0.0 3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CEP19599.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Reprolysin_5 PF13688.6 CEP19600.1 - 6.8e-43 147.1 8.9 6.8e-43 147.1 8.9 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CEP19600.1 - 1.1e-42 146.0 4.9 2e-42 145.1 4.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CEP19600.1 - 1.5e-42 145.7 4.7 2.8e-42 144.8 4.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CEP19600.1 - 4.1e-15 56.4 0.1 1.4e-14 54.7 0.1 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CEP19600.1 - 7.5e-15 55.5 24.4 7.5e-15 55.5 24.4 4.3 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 CEP19600.1 - 2.9e-05 24.3 0.1 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 Reprolysin family propeptide Reprolysin PF01421.19 CEP19600.1 - 0.00042 20.3 10.6 0.007 16.3 10.6 2.6 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease RDD PF06271.12 CEP19601.1 - 8 6.7 11.6 0.55 10.4 1.1 2.3 2 0 0 2 2 2 0 RDD family MMR_HSR1 PF01926.23 CEP19602.1 - 2.5e-13 50.1 0.8 4.1e-06 26.9 0.0 2.6 1 1 1 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP19602.1 - 2.9e-10 40.0 0.2 7.9e-07 28.8 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain KH_2 PF07650.17 CEP19602.1 - 2.4e-09 36.9 0.5 5.4e-09 35.7 0.5 1.7 1 0 0 1 1 1 1 KH domain RsgA_GTPase PF03193.16 CEP19602.1 - 3.1e-07 30.5 0.7 0.003 17.5 0.0 2.6 1 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CEP19602.1 - 3e-06 27.4 0.5 0.00018 21.6 0.1 2.8 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 CEP19602.1 - 3.8e-05 23.6 0.1 0.00044 20.1 0.1 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CEP19602.1 - 4.9e-05 22.9 1.0 0.0033 16.9 0.1 2.5 1 1 1 2 2 2 2 Ferrous iron transport protein B cobW PF02492.19 CEP19602.1 - 0.00069 19.2 0.7 0.018 14.6 0.0 2.6 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CEP19602.1 - 0.00097 18.9 0.0 0.014 15.1 0.0 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CEP19602.1 - 0.0027 18.2 0.0 0.0075 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.20 CEP19602.1 - 0.004 16.4 0.0 0.41 9.8 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 CEP19602.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CEP19602.1 - 0.016 14.7 0.3 0.44 10.0 0.3 2.3 1 1 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.22 CEP19602.1 - 0.017 15.5 0.0 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase GBP PF02263.19 CEP19602.1 - 0.047 13.0 0.0 0.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Roc PF08477.13 CEP19602.1 - 0.074 13.3 0.1 0.69 10.1 0.0 2.4 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NFACT-C PF11923.8 CEP19602.1 - 0.077 12.9 0.9 0.19 11.7 0.9 1.6 1 0 0 1 1 1 0 NFACT protein C-terminal domain Flavoprotein PF02441.19 CEP19603.1 - 3.7e-38 130.7 0.1 2.7e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 Flavoprotein SH3_1 PF00018.28 CEP19603.1 - 2.9e-10 39.6 0.1 5.4e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP19603.1 - 6.9e-09 35.4 0.7 1.2e-08 34.6 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CEP19603.1 - 5.1e-07 29.3 0.0 8.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_4 PF12763.7 CEP19603.1 - 0.0002 21.2 2.2 0.00039 20.3 0.2 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CEP19603.1 - 0.036 13.6 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF4218 PF13960.6 CEP19605.1 - 0.0086 15.7 0.2 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) OrfB_Zn_ribbon PF07282.11 CEP19606.1 - 0.0057 16.5 2.8 0.061 13.2 2.8 2.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain CDC27 PF09507.10 CEP19606.1 - 0.018 14.5 2.5 0.022 14.2 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOG2 PF10428.9 CEP19606.1 - 0.021 14.0 8.2 0.03 13.5 8.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2457 PF10446.9 CEP19606.1 - 0.023 13.9 5.5 0.032 13.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pex14_N PF04695.13 CEP19606.1 - 0.15 12.7 13.4 0.27 11.9 13.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UvrD_C_2 PF13538.6 CEP19607.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Lar_restr_allev PF14354.6 CEP19607.1 - 0.0036 17.6 0.4 0.0071 16.7 0.4 1.5 1 1 0 1 1 1 1 Restriction alleviation protein Lar Herpes_Helicase PF02689.14 CEP19607.1 - 0.011 13.7 0.0 0.015 13.2 0.0 1.1 1 0 0 1 1 1 0 Helicase zf-LITAF-like PF10601.9 CEP19607.1 - 0.039 14.2 1.2 1.8 8.9 0.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Viral_helicase1 PF01443.18 CEP19607.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ogr_Delta PF04606.12 CEP19607.1 - 1.2 9.1 9.1 6.4 6.8 0.5 3.7 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger zf-CCHC PF00098.23 CEP19608.1 - 0.00032 20.7 2.4 0.00056 19.9 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CEP19608.1 - 0.0063 16.2 2.7 0.013 15.2 2.7 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.17 CEP19608.1 - 0.02 15.2 0.0 0.065 13.5 0.0 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein TolA_bind_tri PF16331.5 CEP19610.1 - 0.0067 16.5 0.2 0.011 15.8 0.2 1.4 1 1 0 1 1 1 1 TolA binding protein trimerisation TBCC_N PF16752.5 CEP19610.1 - 0.011 16.2 0.3 0.015 15.8 0.3 1.2 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 CEP19610.1 - 0.014 15.4 0.1 0.017 15.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SpoIIID PF12116.8 CEP19610.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein D Phage_T7_Capsid PF05396.11 CEP19610.1 - 0.081 13.3 0.7 0.13 12.6 0.6 1.3 1 1 0 1 1 1 0 Phage T7 capsid assembly protein DUF3829 PF12889.7 CEP19611.1 - 0.0095 15.4 0.5 0.016 14.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) Myb_DNA-bind_4 PF13837.6 CEP19611.1 - 0.016 15.6 1.1 0.074 13.4 0.2 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3997 PF13162.6 CEP19611.1 - 0.042 14.1 0.3 0.089 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3997) DDE_3 PF13358.6 CEP19613.1 - 5.4e-05 23.0 0.0 0.5 10.1 0.0 2.7 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.6 CEP19613.1 - 0.089 13.4 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.6 CEP19613.1 - 0.11 12.3 0.0 7.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Osw5 PF17062.5 CEP19615.1 - 0.043 13.9 0.6 0.068 13.3 0.6 1.2 1 0 0 1 1 1 0 Outer spore wall 5 Fibroin_P25 PF07294.11 CEP19615.1 - 0.083 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Fibroin P25 LBP_BPI_CETP PF01273.25 CEP19616.1 - 0.081 12.5 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain zf-RING_7 PF02591.15 CEP19616.1 - 0.09 13.0 4.0 5.4 7.3 1.4 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain Helitron_like_N PF14214.6 CEP19617.1 - 2.5e-21 76.8 0.6 3.2e-20 73.2 0.0 2.8 3 1 1 4 4 4 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 CEP19617.1 - 3.3e-15 56.1 0.0 5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP19617.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP19617.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Gar1 PF04410.14 CEP19617.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DUF2075 PF09848.9 CEP19617.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CEP19618.1 - 4.6e-79 266.2 0.0 5.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 CEP19618.1 - 5.1e-06 24.7 0.1 0.00027 19.0 0.1 2.0 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.6 CEP19618.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 CEP19619.1 - 3.6e-71 240.3 0.1 1.1e-70 238.7 0.2 1.7 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.6 CEP19619.1 - 1.2e-66 224.5 0.0 2.9e-33 115.7 0.0 2.5 2 0 0 2 2 2 2 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.14 CEP19619.1 - 5.7e-07 27.9 0.0 8.7e-07 27.3 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 CEP19619.1 - 0.00012 21.9 0.0 0.008 16.0 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain FRG PF08867.11 CEP19619.1 - 0.11 13.5 0.0 21 6.1 0.0 3.0 2 0 0 2 2 2 0 FRG domain DZR PF12773.7 CEP19619.1 - 5.5 7.1 5.5 7.1 6.7 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L32e PF01655.18 CEP19620.1 - 0.02 15.3 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L32 Methyltransf_11 PF08241.12 CEP19624.1 - 3.3e-16 59.7 0.0 7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP19624.1 - 3.7e-14 53.2 0.0 1.4e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP19624.1 - 4.7e-10 39.5 0.0 6.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CEP19624.1 - 5.6e-06 25.9 0.0 1.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CEP19624.1 - 5.9e-06 26.9 0.0 1.4e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CEP19624.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 CEP19624.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 CEP19624.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 CEP19624.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Iron_permease PF04120.12 CEP19625.1 - 3.1e-41 140.1 5.0 1.5e-15 57.1 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease Trep_Strep PF09605.10 CEP19625.1 - 0.23 11.4 4.9 5.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) STIMATE PF12400.8 CEP19626.1 - 6.5e-35 120.4 7.4 6.5e-35 120.4 7.4 1.7 2 0 0 2 2 2 1 STIMATE family MgtC PF02308.16 CEP19626.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 MgtC family Abhydrolase_3 PF07859.13 CEP19627.1 - 1.8e-31 109.6 0.0 4.7e-31 108.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CEP19627.1 - 5.7e-16 58.3 0.8 1.2e-10 40.8 0.2 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 CEP19627.1 - 5.5e-05 22.2 0.6 0.044 12.7 0.0 2.8 3 0 0 3 3 3 2 Carboxylesterase family Peptidase_S9 PF00326.21 CEP19627.1 - 0.0058 16.1 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CEP19627.1 - 0.034 14.8 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SIKE PF05769.11 CEP19628.1 - 7.7e-07 29.2 18.3 1.6e-06 28.2 18.3 1.6 1 1 0 1 1 1 1 SIKE family Cnn_1N PF07989.11 CEP19628.1 - 0.089 13.0 18.2 2.9 8.1 0.2 4.3 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 DpnI_C PF17726.1 CEP19628.1 - 0.09 12.9 2.3 2.1 8.5 0.2 2.7 2 1 0 2 2 2 0 Dam-replacing HTH domain AvrM_N PF18247.1 CEP19628.1 - 0.17 11.9 0.7 0.42 10.6 0.2 2.0 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain CCDC-167 PF15188.6 CEP19628.1 - 0.65 10.4 15.6 0.088 13.2 3.5 3.2 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF745 PF05335.13 CEP19628.1 - 1.4 8.6 11.9 0.31 10.7 5.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) MscS_porin PF12795.7 CEP19628.1 - 3.3 7.2 31.7 0.12 11.9 19.6 2.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF802 PF05650.11 CEP19628.1 - 4.6 7.8 11.5 4 8.0 3.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF802) SpecificRecomb PF10136.9 CEP19628.1 - 4.7 5.4 6.7 0.91 7.8 2.5 1.6 1 1 0 2 2 2 0 Site-specific recombinase DivIC PF04977.15 CEP19628.1 - 7.5 6.4 19.9 5.2 6.9 2.1 3.9 2 1 2 4 4 4 0 Septum formation initiator Caleosin PF05042.13 CEP19630.1 - 9.8e-05 22.3 0.2 0.00048 20.1 0.2 2.0 1 1 0 1 1 1 1 Caleosin related protein Transglycosylas PF06737.14 CEP19630.1 - 0.083 13.6 0.5 0.2 12.3 0.5 1.6 1 0 0 1 1 1 0 Transglycosylase-like domain Sugar_tr PF00083.24 CEP19631.1 - 1.9e-104 350.0 30.7 1e-52 179.5 16.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP19631.1 - 4.8e-29 101.4 28.4 2.1e-28 99.2 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaJ_C PF01556.18 CEP19632.1 - 2.3e-36 125.1 0.0 3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CEP19632.1 - 1.8e-23 82.4 3.4 3.1e-23 81.7 3.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CEP19632.1 - 0.00016 22.0 10.4 0.0003 21.1 10.4 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-C2H2 PF00096.26 CEP19633.1 - 1.8e-05 24.9 0.6 0.0017 18.7 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP19633.1 - 0.00068 20.3 6.6 0.00091 19.9 0.1 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CEP19633.1 - 0.00074 19.8 0.6 0.00074 19.8 0.6 1.9 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CEP19633.1 - 0.0094 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CEP19633.1 - 0.013 15.3 1.3 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) RNA_POL_M_15KD PF02150.16 CEP19633.1 - 0.034 14.0 1.7 0.41 10.6 0.2 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rad50_zn_hook PF04423.14 CEP19633.1 - 0.059 13.2 4.0 0.46 10.4 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif FYDLN_acid PF09538.10 CEP19633.1 - 0.082 13.6 2.7 0.38 11.5 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_12 PF18658.1 CEP19633.1 - 0.093 12.3 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 CEP19633.1 - 0.1 12.8 0.5 0.44 10.7 0.2 1.9 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 CEP19633.1 - 0.18 12.4 3.2 1.2 9.8 0.1 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain CpXC PF14353.6 CEP19633.1 - 0.26 11.3 2.1 0.85 9.7 2.1 2.1 1 1 0 1 1 1 0 CpXC protein zf-BED PF02892.15 CEP19633.1 - 0.51 10.4 4.3 6.5 6.9 0.5 2.3 2 0 0 2 2 2 0 BED zinc finger Gp_dh_C PF02800.20 CEP19634.1 - 3.5e-71 237.9 0.1 5.4e-71 237.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CEP19634.1 - 5.9e-40 135.7 0.1 1.2e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CEP19634.1 - 0.003 17.7 0.2 0.011 15.9 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Peptidase_S26 PF10502.9 CEP19634.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 MOZ_SAS PF01853.18 CEP19635.1 - 0.029 14.0 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family SWIB PF02201.18 CEP19636.1 - 5.7e-16 58.2 0.2 4.5e-15 55.3 0.0 2.6 3 0 0 3 3 3 1 SWIB/MDM2 domain Yip1 PF04893.17 CEP19636.1 - 5.5e-11 42.5 7.8 9.1e-11 41.8 7.8 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2374 PF09574.10 CEP19636.1 - 0.011 15.6 0.1 0.03 14.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) DUF2955 PF11168.8 CEP19636.1 - 0.012 15.4 3.0 0.012 15.4 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) AAA_2 PF07724.14 CEP19637.1 - 1.1e-44 152.5 0.3 9.2e-44 149.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CEP19637.1 - 3.4e-16 59.9 0.1 5.4e-15 56.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CEP19637.1 - 4.7e-12 45.8 0.1 4.7e-12 45.8 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CEP19637.1 - 8e-07 29.1 0.0 2.5e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CEP19637.1 - 3.8e-06 26.4 0.3 0.0012 18.3 0.1 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CEP19637.1 - 2.2e-05 24.2 0.0 0.0092 15.7 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CEP19637.1 - 2.7e-05 24.5 4.6 0.0027 18.0 0.2 3.4 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CEP19637.1 - 4.6e-05 23.5 0.0 0.0024 18.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain ResIII PF04851.15 CEP19637.1 - 5e-05 23.4 1.3 0.43 10.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CEP19637.1 - 0.00015 21.6 0.1 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 CEP19637.1 - 0.00021 21.1 0.8 0.0047 16.7 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 CEP19637.1 - 0.00095 18.3 0.1 0.0084 15.2 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain ABC_tran PF00005.27 CEP19637.1 - 0.0029 18.1 0.3 0.023 15.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 CEP19637.1 - 0.0036 17.1 0.6 0.006 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CEP19637.1 - 0.0038 16.8 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CEP19637.1 - 0.0047 16.8 0.3 0.066 13.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 CEP19637.1 - 0.0062 16.6 0.3 0.031 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CEP19637.1 - 0.0065 16.9 2.5 0.0098 16.3 0.1 2.3 2 1 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 CEP19637.1 - 0.0068 16.6 0.4 0.041 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CEP19637.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CEP19637.1 - 0.013 14.6 1.2 0.015 14.4 0.0 1.6 2 0 0 2 2 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CEP19637.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CEP19637.1 - 0.046 14.3 1.3 0.22 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CEP19637.1 - 0.057 12.6 0.2 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_21 PF13304.6 CEP19637.1 - 0.058 13.2 0.1 0.19 11.5 0.0 1.8 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CEP19637.1 - 0.075 13.5 5.4 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 CEP19637.1 - 0.081 12.2 1.0 0.62 9.3 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region D4 RNA_helicase PF00910.22 CEP19637.1 - 0.15 12.5 0.0 0.5 10.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CEP19637.1 - 0.17 11.8 0.6 0.29 11.0 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 CEP19637.1 - 0.19 11.9 1.2 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_28 PF13521.6 CEP19637.1 - 0.29 11.4 1.7 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.13 CEP19637.1 - 0.33 10.9 10.9 0.51 10.3 10.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 CEP19637.1 - 0.41 10.4 0.0 0.41 10.4 0.0 2.1 3 0 0 3 3 2 0 DEAD/DEAH box helicase Spt20 PF12090.8 CEP19637.1 - 0.45 10.1 10.2 0.72 9.4 10.2 1.3 1 0 0 1 1 1 0 Spt20 family FA_desaturase PF00487.24 CEP19637.1 - 1.5 8.6 5.7 2.4 7.9 5.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Androgen_recep PF02166.16 CEP19637.1 - 8.9 5.0 15.6 17 4.1 15.6 1.4 1 0 0 1 1 1 0 Androgen receptor Gar1 PF04410.14 CEP19639.1 - 5.7e-33 113.9 0.0 7.2e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ARS2 PF04959.13 CEP19640.1 - 1.3e-20 74.6 0.2 1.3e-20 74.6 0.2 1.9 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 CEP19640.1 - 1.5e-19 70.2 6.3 1.5e-19 70.2 6.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 CEP19640.1 - 4.7e-09 35.9 4.4 1.2e-08 34.5 4.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 CEP19640.1 - 0.00027 20.7 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBECR3 PF18812.1 CEP19640.1 - 0.0068 16.3 3.1 0.056 13.4 1.1 2.8 2 0 0 2 2 2 1 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf-C2H2 PF00096.26 CEP19640.1 - 0.13 12.8 0.3 0.13 12.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Med12 PF09497.10 CEP19640.1 - 0.15 12.4 0.1 41 4.6 0.0 2.9 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 Polysacc_deac_1 PF01522.21 CEP19641.1 - 4.5e-24 84.7 0.0 8.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CEP19641.1 - 0.027 13.7 0.0 0.055 12.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Stc1 PF12898.7 CEP19643.1 - 2.7e-19 69.5 7.0 3.7e-19 69.1 7.0 1.1 1 0 0 1 1 1 1 Stc1 domain zf-CRD PF17979.1 CEP19643.1 - 0.1 12.7 8.0 0.29 11.2 8.3 1.6 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zinc_ribbon_12 PF11331.8 CEP19643.1 - 1.5 8.7 6.4 1.5 8.7 2.7 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Pyr_redox_2 PF07992.14 CEP19644.1 - 6.4e-45 153.6 0.0 1e-44 153.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CEP19644.1 - 3.1e-14 53.3 0.1 1.7e-10 41.3 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 CEP19644.1 - 9.9e-11 41.9 1.7 0.00013 22.3 0.1 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CEP19644.1 - 1.4e-10 40.2 2.2 4.1e-05 23.2 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CEP19644.1 - 2.5e-10 39.2 2.4 0.00053 19.3 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CEP19644.1 - 8.3e-07 28.2 0.9 0.052 13.1 0.4 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.6 CEP19644.1 - 3.4e-06 26.5 1.4 0.26 10.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 CEP19644.1 - 0.0095 15.8 1.8 1.9 8.4 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CEP19644.1 - 0.032 14.6 2.7 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region GAS PF13851.6 CEP19644.1 - 0.077 12.3 1.3 0.11 11.8 0.3 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4598 PF15370.6 CEP19646.1 - 1.1e-20 74.1 3.1 1.6e-20 73.6 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DUF2972 PF11186.8 CEP19646.1 - 0.013 15.4 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) DPBB_1 PF03330.18 CEP19647.1 - 6.9e-07 29.5 0.6 2.3e-06 27.8 0.4 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CEP19647.1 - 0.0022 17.8 0.9 0.0031 17.4 0.9 1.2 1 0 0 1 1 1 1 Barwin family Med15_fungi PF05397.12 CEP19648.1 - 3.1e-34 117.6 0.2 3.1e-34 117.6 0.2 11.6 8 4 2 11 11 11 1 Mediator complex subunit 15 Asparaginase PF00710.20 CEP19649.1 - 1.1e-59 201.2 0.0 1.9e-59 200.5 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CEP19649.1 - 2e-31 108.6 0.0 4.9e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CEP19649.1 - 4.9e-17 62.3 0.0 1e-12 48.4 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CEP19649.1 - 1.6e-14 53.8 0.7 2.9e-09 37.0 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CEP19649.1 - 1.7e-13 50.8 0.3 9.4e-06 26.1 0.1 4.3 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CEP19649.1 - 2.5e-09 37.1 0.1 5.3e-06 26.6 0.1 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CEP19649.1 - 1.4e-07 31.2 1.2 0.0009 19.5 0.1 4.4 5 0 0 5 5 5 2 Ankyrin repeat zf-DNL PF05180.12 CEP19649.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 DNL zinc finger Pkinase PF00069.25 CEP19651.1 - 4.6e-53 180.3 1.9 9.1e-51 172.7 1.9 2.1 1 1 0 1 1 1 1 Protein kinase domain PhosphMutase PF10143.9 CEP19651.1 - 1.2e-45 155.4 0.0 2.1e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 CEP19651.1 - 2.7e-24 85.9 0.0 8e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily Pkinase_Tyr PF07714.17 CEP19651.1 - 9.2e-13 48.1 0.7 1.2e-09 37.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CEP19651.1 - 3.6e-05 23.8 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Phosphodiest PF01663.22 CEP19651.1 - 0.00032 20.4 0.1 0.00068 19.3 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase_fungal PF17667.1 CEP19651.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CEP19651.1 - 0.024 14.2 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CEP19651.1 - 0.065 12.6 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tox-REase-9 PF15650.6 CEP19651.1 - 0.19 12.0 0.7 0.53 10.6 0.2 2.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 ABC_membrane PF00664.23 CEP19653.1 - 6.8e-35 121.0 9.8 9.4e-35 120.6 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEP19653.1 - 1.3e-16 61.4 0.0 2.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CEP19654.1 - 3.8e-15 56.3 14.0 5.9e-14 52.4 1.1 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 CEP19654.1 - 1.3e-07 32.2 0.0 4.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter Voldacs PF03517.13 CEP19654.1 - 0.0093 16.1 1.0 0.18 12.0 0.8 2.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Sigma70_ner PF04546.13 CEP19654.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA_25 PF13481.6 CEP19654.1 - 0.021 14.4 1.8 0.3 10.6 0.5 2.9 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CEP19654.1 - 0.034 14.5 0.1 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CEP19654.1 - 0.037 14.5 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NESP55 PF06390.12 CEP19654.1 - 0.049 13.2 2.2 0.088 12.4 2.2 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) AAA_33 PF13671.6 CEP19654.1 - 0.22 11.7 1.1 5.2 7.2 1.1 2.5 1 1 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.14 CEP19654.1 - 6.2 6.6 8.2 4.2 7.1 4.0 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 CEP19654.1 - 6.8 5.9 9.0 13 5.0 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 CEP19654.1 - 8.1 5.5 10.0 13 4.8 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Clathrin_lg_ch PF01086.17 CEP19656.1 - 4.9e-51 174.0 11.3 5.7e-51 173.8 11.3 1.0 1 0 0 1 1 1 1 Clathrin light chain PSII_Pbs27 PF13326.6 CEP19656.1 - 0.0021 18.4 0.5 0.0035 17.7 0.5 1.4 1 0 0 1 1 1 1 Photosystem II Pbs27 CdiI_2 PF18593.1 CEP19656.1 - 0.44 11.2 4.1 17 6.1 0.0 2.9 3 0 0 3 3 3 0 CdiI immunity protein DUF4047 PF13256.6 CEP19656.1 - 4.9 7.4 9.5 14 5.9 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) RNase_PH PF01138.21 CEP19657.1 - 6e-21 75.3 0.0 9.4e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CEP19657.1 - 8.2e-14 51.4 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Enolase_C PF00113.22 CEP19658.1 - 1.2e-154 513.8 0.2 1.6e-154 513.5 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CEP19658.1 - 1.8e-56 189.9 0.0 3.1e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CEP19658.1 - 6.4e-06 25.9 0.1 2.3e-05 24.1 0.0 1.6 1 1 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CEP19658.1 - 0.0032 16.7 0.4 0.019 14.1 0.1 2.1 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DNA_ligase_aden PF01653.18 CEP19658.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aldo_ket_red PF00248.21 CEP19659.1 - 1.3e-22 80.4 0.1 7.1e-21 74.7 0.1 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Syntaxin_2 PF14523.6 CEP19659.1 - 0.025 14.9 0.6 0.31 11.4 0.0 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Rer1 PF03248.13 CEP19660.1 - 1e-58 197.9 2.2 1.5e-58 197.4 2.2 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 CEP19660.1 - 0.065 12.8 1.0 0.11 12.1 1.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Frataxin_Cyay PF01491.16 CEP19661.1 - 7.9e-42 141.7 0.2 9.9e-42 141.4 0.2 1.1 1 0 0 1 1 1 1 Frataxin-like domain NUDIX PF00293.28 CEP19662.1 - 2.8e-07 30.6 0.1 4.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain PAP2_3 PF14378.6 CEP19663.1 - 1.9e-23 83.2 11.2 1.9e-23 83.2 11.2 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 CEP19663.1 - 5.3e-10 39.2 4.4 5.3e-10 39.2 4.4 2.3 2 0 0 2 2 2 1 PAP2 superfamily Oleosin PF01277.17 CEP19663.1 - 3.4 7.4 6.0 7.5 6.3 6.0 1.5 1 0 0 1 1 1 0 Oleosin AAA_lid_2 PF17863.1 CEP19665.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 CEP19665.1 - 0.031 14.3 0.6 0.099 12.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Lipocalin PF00061.23 CEP19665.1 - 0.051 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PAXNEB PF05625.11 CEP19666.1 - 1e-79 268.4 0.0 9.6e-52 176.3 0.0 2.0 1 1 1 2 2 2 2 PAXNEB protein ATPase PF06745.13 CEP19666.1 - 8.8e-05 22.0 0.0 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 KaiC RabGAP-TBC PF00566.18 CEP19667.1 - 2.3e-35 122.2 2.9 2.9e-35 121.9 2.9 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Synaptobrevin PF00957.21 CEP19668.1 - 2.8e-33 113.6 0.7 3.5e-33 113.2 0.7 1.1 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 CEP19668.1 - 0.022 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Ferlin_C PF16165.5 CEP19668.1 - 0.032 14.2 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Ferlin C-terminus UL42 PF17638.2 CEP19668.1 - 0.042 13.8 0.2 0.063 13.2 0.2 1.2 1 0 0 1 1 1 0 HCMV UL42 Glyoxalase_3 PF13468.6 CEP19668.1 - 0.066 13.3 0.3 0.087 12.9 0.3 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain DUF5345 PF17280.2 CEP19668.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) TauE PF01925.19 CEP19668.1 - 0.079 12.6 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Prominin PF05478.11 CEP19668.1 - 0.12 10.3 0.1 0.15 10.0 0.1 1.0 1 0 0 1 1 1 0 Prominin MIG-14_Wnt-bd PF06664.12 CEP19668.1 - 0.18 11.0 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion 4HB_MCP_1 PF12729.7 CEP19668.1 - 0.32 10.5 3.0 0.56 9.7 1.0 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction P33MONOX PF15302.6 CEP19668.1 - 0.62 9.7 4.6 0.97 9.1 4.6 1.3 1 0 0 1 1 1 0 P33 mono-oxygenase Fzo_mitofusin PF04799.13 CEP19668.1 - 1.6 8.3 5.4 0.41 10.2 0.1 2.0 1 1 1 2 2 2 0 fzo-like conserved region F-box-like PF12937.7 CEP19669.1 - 1.6e-06 27.9 0.5 5.1e-06 26.3 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP19669.1 - 0.00014 21.7 0.2 0.00056 19.7 0.2 2.1 1 0 0 1 1 1 1 F-box domain CW_binding_1 PF01473.20 CEP19669.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.5 3 0 0 3 3 3 0 Putative cell wall binding repeat FANCI_S2 PF14676.6 CEP19670.1 - 0.6 10.4 2.0 3.5 7.9 0.3 2.3 2 0 0 2 2 2 0 FANCI solenoid 2 Acetyltransf_1 PF00583.25 CEP19671.1 - 5.9e-14 52.3 0.0 7.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CEP19671.1 - 7.6e-09 35.9 0.1 1e-08 35.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CEP19671.1 - 2e-08 34.2 0.1 2.5e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CEP19671.1 - 8.8e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CEP19671.1 - 4.7e-05 23.6 0.4 6.3e-05 23.1 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MerT PF02411.15 CEP19671.1 - 0.2 11.7 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 MerT mercuric transport protein GCR1_C PF12550.8 CEP19672.1 - 8.1e-08 32.5 0.1 2.1e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 CEP19672.1 - 0.0024 17.0 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Baculo_PEP_C PF04513.12 CEP19672.1 - 0.04 14.0 0.7 0.072 13.1 0.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP PF00616.19 CEP19674.1 - 1.4e-19 70.6 0.0 4.7e-12 46.1 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CEP19674.1 - 1.1e-14 54.8 1.0 1.1e-14 54.8 1.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CEP19674.1 - 0.00014 21.7 0.2 0.00036 20.3 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.6 CEP19674.1 - 0.0069 16.3 0.1 0.0069 16.3 0.1 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal AATF-Che1 PF13339.6 CEP19674.1 - 0.11 13.1 0.0 0.79 10.4 0.0 2.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMEM61 PF15105.6 CEP19675.1 - 0.0067 16.3 0.1 0.042 13.7 0.1 2.1 2 0 0 2 2 2 1 TMEM61 protein family GoLoco PF02188.17 CEP19675.1 - 0.072 12.6 7.9 0.19 11.2 0.4 4.1 4 0 0 4 4 4 0 GoLoco motif Baculo_PEP_C PF04513.12 CEP19676.1 - 0.028 14.5 10.4 0.035 14.1 5.4 2.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 CEP19676.1 - 0.26 11.1 17.6 0.11 12.3 11.7 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Scs3p PF10261.9 CEP19676.1 - 1 8.8 7.5 0.092 12.2 2.1 1.8 1 1 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Laminin_II PF06009.12 CEP19676.1 - 1.4 8.9 10.0 0.18 11.9 3.2 2.3 1 1 1 2 2 2 0 Laminin Domain II Smg4_UPF3 PF03467.15 CEP19677.1 - 1.1e-58 198.1 1.5 1.1e-58 198.1 1.5 3.7 2 2 1 3 3 3 1 Smg-4/UPF3 family SR-25 PF10500.9 CEP19677.1 - 0.0017 18.1 9.9 0.0017 18.1 9.9 3.6 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DASH_Dam1 PF08653.10 CEP19678.1 - 1.3e-14 53.7 0.3 2.2e-14 53.0 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 Mito_carr PF00153.27 CEP19679.1 - 1.1e-66 220.8 1.7 2.3e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.12 CEP19680.1 - 2.2e-37 126.7 14.6 5.7e-06 26.8 0.0 7.3 7 0 0 7 7 7 7 Sel1 repeat DUF4239 PF14023.6 CEP19681.1 - 1.5 8.5 12.1 12 5.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF4407 PF14362.6 CEP19681.1 - 2.9 7.1 26.8 1.8 7.8 17.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CEP19681.1 - 5.4 6.3 38.3 1.1 8.5 9.9 2.1 1 1 1 2 2 2 0 FAM76 protein ATG16 PF08614.11 CEP19681.1 - 5.4 7.2 33.9 4.8 7.4 22.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 CEP19681.1 - 8.4 6.9 12.4 3.7 8.1 5.1 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein MMM1 PF10296.9 CEP19682.1 - 0.0055 15.8 0.0 0.017 14.2 0.0 1.9 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Pre-PUA PF17832.1 CEP19683.1 - 3.1e-26 91.9 0.0 4.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CEP19683.1 - 4.2e-14 52.3 0.1 6.7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CEP19683.1 - 0.014 15.7 0.1 0.032 14.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) HsbA PF12296.8 CEP19683.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A ADH_zinc_N PF00107.26 CEP19686.1 - 4.2e-21 75.3 0.5 6.3e-21 74.7 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CEP19686.1 - 3.2e-08 34.7 0.0 5.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CEP19686.1 - 7.7e-06 25.8 0.4 3.1e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CEP19686.1 - 0.028 13.7 0.7 0.059 12.7 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MgsA_C PF12002.8 CEP19688.1 - 2.6e-59 199.9 0.1 4.1e-59 199.3 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CEP19688.1 - 4.8e-25 87.7 0.2 1.2e-24 86.4 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CEP19688.1 - 1.8e-17 64.0 0.0 4.6e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CEP19688.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CEP19688.1 - 1.4e-07 31.6 0.0 7.3e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CEP19688.1 - 7.2e-06 26.1 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CEP19688.1 - 8.3e-06 26.3 0.4 0.013 15.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 CEP19688.1 - 1.5e-05 24.8 0.0 0.00039 20.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 CEP19688.1 - 0.00022 20.5 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CEP19688.1 - 0.00048 20.3 0.0 0.00088 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CEP19688.1 - 0.00053 19.4 0.1 0.079 12.3 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CEP19688.1 - 0.00054 19.9 0.1 0.92 9.4 0.0 2.4 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CEP19688.1 - 0.00089 19.8 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CEP19688.1 - 0.0011 18.9 0.0 0.004 17.1 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain zf-WRNIP1_ubi PF18279.1 CEP19688.1 - 0.0012 19.3 0.5 0.0045 17.5 0.5 2.1 1 0 0 1 1 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain AAA_22 PF13401.6 CEP19688.1 - 0.0019 18.4 0.2 0.026 14.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CEP19688.1 - 0.0033 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 CEP19688.1 - 0.0042 16.5 0.0 0.04 13.3 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 CEP19688.1 - 0.0047 16.7 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CEP19688.1 - 0.0049 17.4 0.0 0.013 16.0 0.0 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 CEP19688.1 - 0.0063 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 CEP19688.1 - 0.0078 16.6 0.0 0.03 14.7 0.0 2.1 3 0 0 3 3 1 1 RNA helicase Sigma54_activ_2 PF14532.6 CEP19688.1 - 0.0085 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.6 CEP19688.1 - 0.012 16.0 0.3 0.69 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 CEP19688.1 - 0.025 14.6 0.1 6 6.8 0.1 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 CEP19688.1 - 0.031 14.4 0.1 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 CEP19688.1 - 0.072 12.8 0.0 0.31 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP19688.1 - 0.088 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CEP19688.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 CEP19688.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CEP19688.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 CEP19688.1 - 0.17 11.4 0.0 0.59 9.6 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Med11 PF10280.9 CEP19689.1 - 4.5e-08 33.6 1.2 6.4e-08 33.1 1.2 1.3 1 0 0 1 1 1 1 Mediator complex protein Sec7 PF01369.20 CEP19690.1 - 1.4e-35 122.6 0.1 3.1e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CEP19690.1 - 1.6e-14 54.3 0.1 1.6e-12 47.9 0.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CEP19690.1 - 5.2e-08 33.3 0.0 1.1e-05 25.9 0.0 2.8 2 0 0 2 2 2 1 PH domain MPM1 PF17234.2 CEP19690.1 - 0.016 15.5 1.9 0.016 15.5 1.9 2.8 3 1 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 HipN PF18253.1 CEP19690.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain DFRP_C PF16543.5 CEP19690.1 - 0.18 12.3 3.1 6.2 7.4 0.7 2.8 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Spt20 PF12090.8 CEP19690.1 - 0.19 11.3 23.4 0.51 9.9 3.1 3.0 2 0 0 2 2 2 0 Spt20 family MecA PF05389.12 CEP19690.1 - 3.8 7.1 9.5 0.066 12.8 0.5 2.4 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) LNP1 PF15419.6 CEP19690.1 - 8.4 6.6 14.8 0.076 13.2 0.8 2.9 3 0 0 3 3 3 0 Leukemia NUP98 fusion partner 1 Retrotrans_gag PF03732.17 CEP19691.1 - 1.8e-05 25.0 0.3 4.3e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Cytochrom_B558a PF05038.13 CEP19691.1 - 0.13 11.8 0.3 0.26 10.9 0.3 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit HORMA PF02301.18 CEP19692.1 - 0.039 13.5 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 HORMA domain Phage_T7_tail PF03906.14 CEP19692.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage T7 tail fibre protein MDM31_MDM32 PF08118.11 CEP19693.1 - 1.6e-170 568.3 0.0 4.9e-170 566.7 0.0 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF5052 PF16475.5 CEP19694.1 - 0.0065 16.1 0.1 0.0097 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5052) CK_II_beta PF01214.18 CEP19696.1 - 9.7e-83 276.4 0.1 1.2e-82 276.2 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 CEP19696.1 - 0.016 15.3 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Glyco_hydro_100 PF12899.7 CEP19696.1 - 0.021 13.5 0.1 0.031 13.0 0.1 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase SH3_14 PF18343.1 CEP19696.1 - 0.064 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Dda helicase SH3 domain DUF5052 PF16475.5 CEP19697.1 - 0.0034 17.0 0.2 0.0045 16.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5052) Kelch_5 PF13854.6 CEP19700.1 - 4.5e-11 42.5 4.4 0.0011 18.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CEP19700.1 - 7.2e-09 35.5 7.5 0.37 10.8 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CEP19700.1 - 3.6e-08 33.4 10.5 0.022 15.1 0.5 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CEP19700.1 - 3e-07 29.9 4.2 0.072 12.7 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CEP19700.1 - 0.00013 21.8 1.5 10 6.3 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CEP19700.1 - 0.001 19.3 14.4 1.9 8.9 0.5 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Gram_pos_anchor PF00746.21 CEP19700.1 - 0.1 12.5 1.7 0.22 11.5 1.7 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PPR_2 PF13041.6 CEP19701.1 - 2.8e-29 101.0 8.3 6.8e-12 45.4 0.0 6.0 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 CEP19701.1 - 4.1e-23 81.2 3.6 4.4e-05 23.5 0.0 6.0 4 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 CEP19701.1 - 2.1e-14 52.7 15.7 8.8e-06 25.6 0.1 7.3 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 CEP19701.1 - 2.1e-12 46.9 0.2 4.3e-08 32.8 0.0 3.3 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CEP19701.1 - 2.2e-11 43.3 12.8 0.00014 21.4 0.0 6.3 7 0 0 7 7 7 3 PPR repeat RPM2 PF08579.11 CEP19701.1 - 0.0038 17.6 7.5 0.12 12.8 0.8 4.1 3 2 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 CEP19701.1 - 0.12 12.3 2.5 0.93 9.4 0.1 3.4 3 1 1 4 4 4 0 Mitochondrial ATPase expression TPR_14 PF13428.6 CEP19701.1 - 0.15 12.9 0.0 87 4.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_18 PF13238.6 CEP19702.1 - 0.00031 21.3 0.1 0.0012 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 CEP19702.1 - 0.00046 20.0 0.1 0.0018 18.1 0.1 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CEP19702.1 - 0.0075 16.4 0.0 0.026 14.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CEP19702.1 - 0.016 15.0 0.3 0.063 13.0 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 CEP19702.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NAD_Gly3P_dh_N PF01210.23 CEP19703.1 - 2.9e-51 173.6 0.1 1.1e-50 171.6 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CEP19703.1 - 6.3e-49 165.9 0.1 1.6e-48 164.6 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CEP19703.1 - 0.0015 19.1 0.0 2.1 9.0 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CEP19703.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRAPPC-Trs85 PF12739.7 CEP19704.1 - 5.9e-111 371.3 2.1 1.6e-110 369.9 2.1 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_2 PF07719.17 CEP19704.1 - 0.043 13.9 0.3 0.73 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 CEP19704.1 - 0.13 11.7 1.0 0.72 9.2 0.3 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Cnd3 PF12719.7 CEP19705.1 - 1.3e-58 198.6 13.8 1.7e-40 139.1 0.9 4.6 3 2 1 4 4 4 2 Nuclear condensing complex subunits, C-term domain RabGAP-TBC PF00566.18 CEP19705.1 - 4.6e-16 59.1 4.8 4.6e-16 59.1 4.8 4.0 3 1 0 3 3 3 1 Rab-GTPase-TBC domain HEAT_2 PF13646.6 CEP19705.1 - 1.3e-05 25.5 1.1 0.48 10.9 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CEP19705.1 - 0.001 19.2 4.5 5.4 7.6 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat BUD22 PF09073.10 CEP19705.1 - 0.0095 15.3 43.7 0.014 14.7 6.9 2.6 3 0 0 3 3 3 2 BUD22 Cnd1 PF12717.7 CEP19705.1 - 0.069 13.2 11.8 0.17 11.9 0.0 4.4 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Apis_Csd PF11671.8 CEP19705.1 - 0.53 10.3 2.7 1.3 9.1 2.7 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein Neur_chan_memb PF02932.16 CEP19705.1 - 0.7 9.9 9.2 1.4 8.9 0.6 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EF1G PF00647.19 CEP19706.1 - 2.9e-46 155.9 0.8 5.6e-46 155.0 0.8 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CEP19706.1 - 4.7e-12 46.0 0.1 1.6e-11 44.3 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CEP19706.1 - 2e-11 44.1 0.6 8e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CEP19706.1 - 4.9e-07 29.9 0.2 1.5e-06 28.3 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CEP19706.1 - 1.3e-05 25.1 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CEP19706.1 - 0.00029 21.2 0.2 0.00087 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CEP19706.1 - 0.0026 17.5 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 CEP19706.1 - 1.2 9.8 6.1 3.7 8.2 6.1 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PAS_9 PF13426.7 CEP19707.1 - 8.3e-30 103.1 0.0 1.3e-14 54.3 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 CEP19707.1 - 3.5e-21 75.3 0.0 4.2e-15 55.8 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 CEP19707.1 - 5.5e-18 65.0 0.0 9.3e-08 32.1 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 CEP19707.1 - 9.7e-13 48.2 0.0 5.5e-09 36.1 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 CEP19707.1 - 1.2e-11 44.8 0.0 0.00011 22.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_2 PF08446.11 CEP19707.1 - 7.3e-05 23.4 0.0 1.4 9.6 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 CEP19707.1 - 0.002 18.1 0.0 0.83 9.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain DPPIV_N PF00930.21 CEP19708.1 - 3.9e-53 180.5 5.8 3.9e-53 180.5 5.8 2.0 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CEP19708.1 - 1.5e-30 106.3 0.0 7.3e-30 104.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CEP19708.1 - 1.8e-05 24.5 0.1 8.1e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CEP19708.1 - 9.4e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 CEP19708.1 - 0.00016 21.4 0.0 0.00045 19.9 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CEP19708.1 - 0.0099 16.5 0.0 0.022 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CEP19708.1 - 0.033 13.5 0.0 0.093 12.0 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 CEP19708.1 - 0.13 10.9 0.0 0.3 9.7 0.0 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mucin PF01456.17 CEP19708.1 - 1.9 8.5 28.4 0.069 13.1 21.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 CEP19708.1 - 8.4 4.5 15.6 17 3.4 15.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RVT_1 PF00078.27 CEP19709.1 - 9.1e-35 120.2 0.0 1.6e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP19709.1 - 4.1e-07 30.6 0.8 1.3e-06 29.1 0.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP19709.1 - 0.0055 16.3 0.1 0.018 14.6 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP19709.1 - 0.011 15.5 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 CEP19709.1 - 0.016 15.3 1.2 0.016 15.3 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF4317 PF14199.6 CEP19710.1 - 0.054 12.6 0.1 0.11 11.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) HTH_28 PF13518.6 CEP19711.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MULE PF10551.9 CEP19712.1 - 2.3e-27 95.2 0.3 6.2e-27 93.9 0.3 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CEP19712.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Condensation PF00668.20 CEP19712.1 - 0.038 12.6 1.6 0.093 11.4 1.6 1.6 1 0 0 1 1 1 0 Condensation domain CRAL_TRIO_2 PF13716.6 CEP19713.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain M64_N PF16217.5 CEP19713.1 - 0.12 11.9 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase M64 N-terminus MS_channel PF00924.18 CEP19714.1 - 7.5e-16 58.3 0.3 1.4e-15 57.4 0.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CEP19714.1 - 0.00013 21.2 0.3 0.00013 21.2 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CEP19714.1 - 0.00028 20.6 0.2 0.00028 20.6 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CEP19714.1 - 0.002 17.6 0.4 0.007 15.8 0.4 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CEP19714.1 - 0.0055 17.1 2.1 0.15 12.5 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CEP19714.1 - 0.027 14.3 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Chitin_synth_2 PF03142.15 CEP19715.1 - 1.5e-245 815.8 1.1 2.2e-245 815.3 1.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CEP19715.1 - 1.1e-09 38.6 7.5 5.2e-09 36.3 7.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CEP19715.1 - 1.8e-09 37.8 0.0 5e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DNA_pol_A_exo1 PF01612.20 CEP19718.1 - 0.00073 19.3 0.0 0.0015 18.3 0.0 1.5 2 0 0 2 2 2 1 3'-5' exonuclease Poxvirus_B22R_C PF13168.6 CEP19719.1 - 0.026 14.0 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Sugar_tr PF00083.24 CEP19720.1 - 4.1e-91 306.1 22.5 5.6e-66 223.3 10.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CEP19720.1 - 2.1e-17 63.1 11.1 2.1e-17 63.1 11.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily PSI PF01437.25 CEP19720.1 - 0.00016 22.1 3.8 0.00026 21.5 3.8 1.3 1 0 0 1 1 1 1 Plexin repeat FA_desaturase PF00487.24 CEP19720.1 - 0.14 11.9 2.5 0.72 9.6 0.8 2.3 2 0 0 2 2 2 0 Fatty acid desaturase GST_N_3 PF13417.6 CEP19721.1 - 3.4e-13 49.8 0.0 5.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CEP19721.1 - 2.1e-08 34.0 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CEP19721.1 - 1e-07 32.1 0.2 1.8e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CEP19721.1 - 8.1e-05 22.9 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CEP19721.1 - 0.00024 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CEP19721.1 - 0.00032 20.8 0.0 0.0006 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AstE_AspA PF04952.14 CEP19722.1 - 8.5e-32 110.4 0.0 5e-31 107.9 0.0 2.2 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 CEP19722.1 - 9.7e-24 84.3 0.0 2.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 HutD DUF2817 PF10994.8 CEP19722.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Spt20 PF12090.8 CEP19722.1 - 0.18 11.4 8.6 0.3 10.7 8.6 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 CEP19722.1 - 0.56 10.2 8.7 0.85 9.5 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 CEP19722.1 - 0.61 8.9 5.9 0.98 8.2 5.9 1.3 1 0 0 1 1 1 0 Androgen receptor DUF2967 PF11179.8 CEP19722.1 - 4.2 5.3 6.5 6 4.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Lactamase_B_2 PF12706.7 CEP19723.1 - 1.4e-28 99.8 0.1 5.1e-27 94.7 0.1 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CEP19723.1 - 8.2e-10 38.8 0.0 1.2e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Na_Ca_ex PF01699.24 CEP19724.1 - 7.2e-21 74.7 18.1 7.2e-21 74.7 18.1 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein MLANA PF14991.6 CEP19724.1 - 0.21 11.9 0.5 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein melan-A Zn_clus PF00172.18 CEP19725.1 - 8.4e-10 38.6 14.8 1.6e-09 37.7 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.9 CEP19725.1 - 7.4 4.7 21.7 8.9 4.4 21.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPMT PF05724.11 CEP19726.1 - 1.2e-34 119.9 0.0 2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 CEP19726.1 - 2.5e-07 31.3 0.0 1.1e-06 29.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CEP19726.1 - 0.00027 21.5 0.0 0.002 18.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CEP19726.1 - 0.00088 19.1 0.0 0.0046 16.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain SAS-6_N PF16531.5 CEP19726.1 - 0.0065 17.0 0.1 0.014 16.0 0.1 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Methyltransf_12 PF08242.12 CEP19726.1 - 0.023 15.4 0.0 0.098 13.4 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19726.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 CEP19727.1 - 1.8e-73 246.5 0.1 2.5e-73 246.1 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 CEP19727.1 - 0.00033 20.4 0.1 0.00082 19.1 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 CEP19727.1 - 0.0031 16.8 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 CEP19727.1 - 0.023 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MMS22L_C PF14911.6 CEP19728.1 - 0.016 14.3 0.7 0.018 14.2 0.7 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Calc_CGRP_IAPP PF00214.19 CEP19728.1 - 0.2 12.0 0.3 9.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family VAR1 PF05316.12 CEP19729.1 - 0.0055 15.8 0.7 0.0055 15.8 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) RNB PF00773.19 CEP19730.1 - 2.5e-58 198.0 0.1 5.9e-58 196.7 0.1 1.6 1 1 0 1 1 1 1 RNB domain DNA_pol3_delt_C PF14840.6 CEP19730.1 - 0.14 12.5 0.2 0.3 11.4 0.2 1.5 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term 3HCDH_N PF02737.18 CEP19731.1 - 9.9e-60 201.5 3.5 1.4e-59 201.0 3.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CEP19731.1 - 1.7e-32 111.9 0.1 6e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CEP19731.1 - 1.2e-05 25.5 3.7 0.00036 20.7 3.7 2.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 CEP19731.1 - 0.00013 21.3 0.1 0.00017 20.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CEP19731.1 - 0.00016 21.0 3.5 0.00038 19.8 2.4 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 CEP19731.1 - 0.0032 17.4 0.8 0.007 16.4 0.8 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 CEP19731.1 - 0.0056 16.2 0.1 0.0073 15.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CEP19731.1 - 0.013 15.8 0.9 0.035 14.4 0.9 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CEP19731.1 - 0.025 15.0 0.5 0.046 14.2 0.5 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 CEP19731.1 - 0.027 15.0 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 CEP19731.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CEP19731.1 - 0.065 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 CEP19731.1 - 0.079 13.7 0.3 0.3 11.8 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.6 CEP19731.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PglD_N PF17836.1 CEP19731.1 - 0.22 12.2 1.4 0.74 10.5 0.2 2.2 1 1 1 2 2 2 0 PglD N-terminal domain F420_oxidored PF03807.17 CEP19731.1 - 0.29 11.7 3.3 2.2 8.9 3.3 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CEP19731.1 - 0.75 9.9 4.8 4 7.5 0.6 2.8 1 1 2 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF89 PF01937.19 CEP19732.1 - 3.3e-112 374.9 2.7 3.8e-112 374.7 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Desulfoferrod_N PF06397.12 CEP19733.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Phage_holin_2_4 PF16082.5 CEP19733.1 - 2.2 8.1 7.0 11 5.9 6.2 2.3 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ferric_reduct PF01794.19 CEP19734.1 - 1e-19 70.8 8.8 3.3e-19 69.2 8.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CEP19734.1 - 1.3e-15 57.8 0.2 3.1e-13 50.1 0.0 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CEP19734.1 - 1.2e-05 25.3 0.1 3.4e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 FAD-binding domain LPD7 PF18821.1 CEP19734.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 Calreticulin PF00262.18 CEP19736.1 - 4e-77 259.6 20.9 2.2e-59 201.2 4.1 2.7 2 1 1 3 3 3 2 Calreticulin family HTH_23 PF13384.6 CEP19738.1 - 0.00011 21.9 0.1 0.0075 16.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CEP19738.1 - 0.0041 17.7 0.0 0.0098 16.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 CEP19738.1 - 0.0048 17.0 0.2 0.036 14.2 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Stork_head PF10264.9 CEP19738.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Fimbrial_PilY2 PF14481.6 CEP19739.1 - 0.048 13.3 0.1 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 NDUF_B4 PF07225.12 CEP19739.1 - 0.15 11.9 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) OrfB_Zn_ribbon PF07282.11 CEP19739.1 - 0.31 11.0 6.6 0.32 11.0 3.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF4611 PF15387.6 CEP19740.1 - 0.00021 21.5 9.7 11 6.3 0.0 8.3 9 0 0 9 9 9 2 Domain of unknown function (DUF4611) MDM31_MDM32 PF08118.11 CEP19740.1 - 0.051 12.3 0.1 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins ApoC-I PF04691.12 CEP19740.1 - 0.1 12.5 0.3 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Presenilin PF01080.17 CEP19741.1 - 6.5e-98 328.1 2.0 9.3e-98 327.6 2.0 1.2 1 0 0 1 1 1 1 Presenilin Sarcoglycan_1 PF04790.13 CEP19741.1 - 0.4 10.0 0.0 0.4 10.0 0.0 2.0 3 0 0 3 3 3 0 Sarcoglycan complex subunit protein PEMT PF04191.13 CEP19742.1 - 4.6e-35 120.2 3.9 9.5e-35 119.2 3.9 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase RNA_capsid PF03035.14 CEP19743.1 - 0.029 14.4 0.9 0.041 13.9 0.9 1.2 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein SR-25 PF10500.9 CEP19743.1 - 0.11 12.0 6.0 0.18 11.4 6.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PT PF04886.12 CEP19744.1 - 5.9 6.5 7.0 5.3 6.7 1.2 2.8 2 0 0 2 2 2 0 PT repeat DUF3439 PF11921.8 CEP19745.1 - 0.25 11.3 5.9 0.46 10.5 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CEP19745.1 - 5.8 5.0 9.5 8.1 4.5 9.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ank_2 PF12796.7 CEP19746.1 - 1.5e-18 67.1 2.2 5.6e-08 33.3 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP19746.1 - 7.2e-16 58.3 0.6 8.9e-07 29.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CEP19746.1 - 4.6e-14 51.1 8.1 4.4e-06 26.6 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CEP19746.1 - 9.1e-13 48.2 1.8 1e-06 28.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CEP19746.1 - 1.1e-11 44.6 7.3 1.4e-05 25.3 0.2 4.1 5 0 0 5 5 5 2 Ankyrin repeat SUIM_assoc PF16619.5 CEP19746.1 - 0.043 13.9 6.4 0.11 12.6 6.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3665 PF12427.8 CEP19747.1 - 0.17 11.6 0.4 0.39 10.5 0.4 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase YqzL PF14006.6 CEP19749.1 - 0.048 14.0 0.2 0.12 12.8 0.2 1.7 1 1 0 1 1 1 0 YqzL-like protein WD40 PF00400.32 CEP19750.1 - 6.9e-27 93.2 4.9 8.2e-09 36.0 0.7 3.1 2 1 1 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19750.1 - 4.7e-08 33.2 0.3 0.001 19.4 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP19750.1 - 4.8e-05 23.3 0.1 0.00029 20.8 0.1 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CEP19750.1 - 0.0036 16.0 0.3 0.15 10.7 0.3 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.12 CEP19750.1 - 0.088 12.8 1.8 0.6 10.1 0.1 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Spore_coat_CotO PF14153.6 CEP19750.1 - 0.74 9.7 5.6 1 9.3 5.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO WD40 PF00400.32 CEP19751.1 - 4.7e-10 39.9 0.3 4.4e-09 36.8 0.3 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19751.1 - 0.0034 17.7 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CEP19751.1 - 0.041 12.5 0.6 0.084 11.5 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF5336 PF17270.2 CEP19751.1 - 0.14 11.8 0.4 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) AAA_23 PF13476.6 CEP19752.1 - 0.013 16.0 0.3 0.013 16.0 0.3 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 CEP19752.1 - 0.015 15.4 6.1 0.021 14.9 6.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.13 CEP19752.1 - 0.022 15.2 3.2 0.038 14.5 3.2 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 sCache_2 PF17200.4 CEP19752.1 - 0.19 11.6 2.2 0.61 9.9 2.0 1.8 1 1 1 2 2 2 0 Single Cache domain 2 ZapB PF06005.12 CEP19752.1 - 0.26 11.8 12.2 0.41 11.1 12.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 CEP19752.1 - 0.65 10.3 7.0 0.9 9.9 5.6 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Med30 PF11315.8 CEP19754.1 - 0.015 15.5 0.1 0.019 15.1 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF2023 PF09633.10 CEP19754.1 - 0.096 12.8 0.1 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2023) zf-C2H2_4 PF13894.6 CEP19755.1 - 0.12 13.3 1.5 0.51 11.3 1.5 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger HTH_23 PF13384.6 CEP19756.1 - 2.5e-07 30.3 0.0 0.00032 20.4 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_17 PF12728.7 CEP19756.1 - 7.7e-06 26.0 0.0 0.054 13.7 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.6 CEP19756.1 - 1.4e-05 25.1 0.1 0.00039 20.5 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 CEP19756.1 - 0.00035 20.5 0.3 0.025 14.6 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CEP19756.1 - 0.0055 17.0 0.1 0.015 15.6 0.0 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.18 CEP19756.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 0 Transposase HTH_32 PF13565.6 CEP19756.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 CEP19756.1 - 0.041 13.3 0.1 0.091 12.2 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 LZ_Tnp_IS481 PF13011.6 CEP19756.1 - 0.062 13.8 0.1 0.17 12.4 0.0 1.7 2 1 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_23 PF13384.6 CEP19757.1 - 0.0005 19.8 0.1 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain RPN1_RPN2_N PF17781.1 CEP19757.1 - 0.031 13.7 0.2 0.04 13.3 0.2 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain HTH_Tnp_ISL3 PF13542.6 CEP19757.1 - 0.048 13.1 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 CEP19757.1 - 0.096 12.8 0.2 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_41 PF13844.6 CEP19757.1 - 0.14 10.6 0.8 0.49 8.8 0.1 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 41 Aldedh PF00171.22 CEP19758.1 - 2.5e-167 557.1 1.2 2.8e-167 556.9 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CEP19758.1 - 0.1 12.0 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Melibiase PF02065.18 CEP19759.1 - 4.5e-18 65.3 0.2 9.7e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 CEP19759.1 - 4e-07 29.6 0.1 6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 CEP19759.1 - 1.8e-05 24.0 0.1 0.0019 17.4 0.1 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Glyco_hydro_18 PF00704.28 CEP19760.1 - 5.4e-16 59.2 0.0 6.4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BRAP2 PF07576.12 CEP19761.1 - 4.6e-25 87.7 0.0 1.2e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CEP19761.1 - 6.1e-19 68.1 4.7 2.4e-18 66.2 4.7 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Cortex-I_coil PF09304.10 CEP19761.1 - 0.0017 18.6 12.8 0.0039 17.4 12.8 1.7 1 0 0 1 1 1 1 Cortexillin I, coiled coil UPF0242 PF06785.11 CEP19761.1 - 0.0084 16.2 13.2 0.021 14.9 13.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus RRM_1 PF00076.22 CEP19761.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Csm1_N PF18504.1 CEP19761.1 - 0.024 14.9 7.2 0.024 14.9 7.2 3.9 4 1 0 4 4 4 0 Csm1 N-terminal domain Rootletin PF15035.6 CEP19761.1 - 1.3 9.0 20.5 0.44 10.6 9.5 2.8 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion zf-C3HC4_3 PF13920.6 CEP19761.1 - 6.5 6.7 26.3 6 6.8 12.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 CEP19762.1 - 1.1e-07 31.6 0.9 8e-07 28.9 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CEP19762.1 - 0.0011 18.8 0.2 0.0035 17.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain Imm41 PF15592.6 CEP19762.1 - 0.0033 17.8 0.4 0.012 15.9 0.4 2.0 1 0 0 1 1 1 1 Immunity protein 41 NADH-u_ox-rdase PF10785.9 CEP19763.1 - 9.5e-31 106.3 0.2 1.3e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 CEP19763.1 - 6.2e-19 67.8 0.1 8.2e-19 67.4 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Peptidase_C13 PF01650.18 CEP19764.1 - 4.8e-45 154.1 0.6 5.8e-45 153.8 0.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 CEP19764.1 - 0.0072 16.6 0.0 0.031 14.5 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute PDEase_I PF00233.19 CEP19765.1 - 2.6e-75 253.2 0.2 1.4e-74 250.8 0.0 2.3 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 CEP19765.1 - 1.7e-06 28.2 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PriC PF07445.12 CEP19765.1 - 0.01 15.8 0.1 0.01 15.8 0.1 2.6 3 0 0 3 3 3 0 Primosomal replication protein priC Mt_ATP-synt_B PF05405.14 CEP19765.1 - 0.017 14.7 1.4 0.39 10.3 0.5 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cnn_1N PF07989.11 CEP19766.1 - 1.2e-09 38.2 9.3 1.9e-09 37.5 9.3 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Cep57_CLD_2 PF14197.6 CEP19766.1 - 0.059 13.5 4.3 0.059 13.5 4.3 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 CEP19766.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 CEP19766.1 - 2.1 8.5 5.8 4 7.6 0.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor Pkinase PF00069.25 CEP19767.1 - 1.9e-71 240.5 0.0 2.5e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19767.1 - 2e-32 112.5 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CEP19767.1 - 2.1e-11 44.3 2.7 2.2e-10 41.0 3.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CEP19767.1 - 3.2e-05 23.1 0.0 5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CEP19767.1 - 0.0034 16.7 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 CEP19767.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 C2 domain Urm1 PF09138.11 CEP19768.1 - 4.9e-36 123.0 0.7 5.5e-36 122.8 0.7 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CEP19768.1 - 5.8e-05 23.7 0.0 6.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family Per1 PF04080.13 CEP19768.1 - 0.024 14.4 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Per1-like family Stap_Strp_tox_C PF02876.17 CEP19768.1 - 0.03 14.6 0.2 0.039 14.3 0.2 1.1 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain NAD_binding_10 PF13460.6 CEP19769.1 - 9.5e-17 61.5 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CEP19769.1 - 2e-05 24.3 0.2 2.9e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 CEP19769.1 - 0.0003 21.3 0.3 0.00056 20.4 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 CEP19769.1 - 0.00062 19.9 0.1 0.0011 19.1 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 CEP19769.1 - 0.0011 18.4 0.1 0.0016 18.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CEP19769.1 - 0.0069 15.9 0.2 0.0097 15.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CEP19769.1 - 0.0087 15.2 0.2 0.019 14.0 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain DFP PF04127.15 CEP19769.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.24 CEP19769.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CEP19769.1 - 0.054 13.4 0.2 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 CEP19769.1 - 0.062 14.0 0.2 0.17 12.5 0.2 1.7 1 0 0 1 1 1 0 PglD N-terminal domain CoA_binding_2 PF13380.6 CEP19769.1 - 0.16 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Cyclin_N PF00134.23 CEP19770.1 - 6.7e-16 58.2 0.0 8.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CEP19770.1 - 1.9e-07 31.6 0.0 2.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin EXS PF03124.14 CEP19771.1 - 2e-90 303.5 27.7 2.6e-90 303.1 27.7 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CEP19771.1 - 1e-46 160.6 18.1 1.4e-24 87.8 11.1 2.9 1 1 1 2 2 2 2 SPX domain LidA_Long_CC PF18641.1 CEP19771.1 - 0.29 11.2 2.3 12 5.9 0.2 2.2 2 0 0 2 2 2 0 LidA long coiled-coil domain Xan_ur_permease PF00860.20 CEP19772.1 - 1.9e-83 280.3 39.4 2.4e-83 280.0 39.4 1.0 1 0 0 1 1 1 1 Permease family Got1 PF04178.12 CEP19773.1 - 7.2e-22 78.0 17.4 9.5e-22 77.6 17.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF202 PF02656.15 CEP19773.1 - 5.1 7.6 9.5 1.4 9.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4167 PF13763.6 CEP19775.1 - 0.0093 16.1 0.0 2.5 8.3 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4167) DDE_Tnp_1_7 PF13843.6 CEP19776.1 - 6.5e-43 147.4 0.0 7.6e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 CEP19776.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain FapA PF03961.13 CEP19778.1 - 0.065 11.8 0.9 0.075 11.6 0.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Nucleoporin_FG2 PF15967.5 CEP19778.1 - 0.17 10.4 0.3 0.21 10.1 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Transposase_21 PF02992.14 CEP19781.1 - 0.0014 17.9 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 TLP-20 PF06088.11 CEP19781.1 - 0.034 14.0 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HTH_11 PF08279.12 CEP19781.1 - 0.19 11.7 0.1 20 5.2 0.0 2.5 2 0 0 2 2 2 0 HTH domain Pkinase PF00069.25 CEP19782.1 - 2.3e-53 181.3 0.0 2.5e-32 112.3 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19782.1 - 2.4e-27 95.9 0.0 1.2e-18 67.4 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Response_reg PF00072.24 CEP19782.1 - 3.7e-14 52.8 0.6 1e-13 51.4 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain DUF465 PF04325.13 CEP19782.1 - 0.058 13.4 1.3 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) C2 PF00168.30 CEP19783.1 - 1.4e-13 51.0 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain TrbE PF11100.8 CEP19784.1 - 0.031 14.5 4.3 0.45 10.8 0.0 2.4 1 1 1 2 2 2 0 Conjugal transfer protein TrbE RVT_1 PF00078.27 CEP19785.1 - 1.3e-06 28.1 0.0 3e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CEP19786.1 - 1.5e-27 96.6 0.1 2e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lambda_Kil PF06301.11 CEP19786.1 - 0.0085 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage lambda Kil protein DUF3858 PF12970.7 CEP19787.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) KORA PF16509.5 CEP19787.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HSP20 PF00011.21 CEP19789.1 - 1.7e-17 63.4 0.1 3e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Taeniidae_ag PF05596.11 CEP19789.1 - 8.1e-11 41.7 0.1 0.25 11.4 0.0 6.9 6 1 1 7 7 7 3 Taeniidae antigen CBM_19 PF03427.13 CEP19789.1 - 6.8e-08 32.4 12.6 2.1 8.4 0.0 6.9 7 1 0 7 7 7 4 Carbohydrate binding domain (family 19) ArsA_HSP20 PF17886.1 CEP19789.1 - 3.8e-06 26.3 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GN3L_Grn1 PF08701.11 CEP19789.1 - 3.9e-06 26.9 0.2 19 5.5 0.0 5.4 5 0 0 5 5 5 1 GNL3L/Grn1 putative GTPase CS PF04969.16 CEP19789.1 - 0.0038 18.2 0.1 0.0062 17.5 0.1 1.3 1 0 0 1 1 1 1 CS domain BON PF04972.17 CEP19789.1 - 0.077 13.3 0.1 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 BON domain DNA_pol3_delta2 PF13177.6 CEP19789.1 - 0.35 10.6 7.7 12 5.6 0.1 3.9 1 1 3 4 4 4 0 DNA polymerase III, delta subunit adh_short_C2 PF13561.6 CEP19790.1 - 4.3e-53 180.3 2.0 5.8e-53 179.8 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP19790.1 - 1.3e-43 148.8 0.6 1.7e-43 148.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP19790.1 - 3.8e-15 56.3 0.5 5.1e-15 55.8 0.5 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CEP19790.1 - 0.006 16.8 0.1 0.013 15.7 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Ysc84 PF04366.12 CEP19790.1 - 0.014 15.1 0.5 0.071 12.9 0.1 2.1 2 1 0 2 2 2 0 Las17-binding protein actin regulator His_biosynth PF00977.21 CEP19790.1 - 0.095 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Sec23_trunk PF04811.15 CEP19791.1 - 1.2e-59 201.9 0.0 2.1e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CEP19791.1 - 5.6e-14 51.8 0.1 1.2e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CEP19791.1 - 1.3e-13 50.7 3.0 3.3e-13 49.4 3.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CEP19791.1 - 2.9e-13 50.4 0.0 7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CEP19791.1 - 2.2e-10 40.3 0.0 5.6e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Fer2_3 PF13085.6 CEP19792.1 - 7.8e-33 112.8 0.1 1.3e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CEP19792.1 - 3.2e-09 37.2 7.9 3.2e-09 37.2 7.9 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CEP19792.1 - 2.7e-07 30.9 12.1 5.1e-07 30.1 9.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CEP19792.1 - 1e-06 28.7 4.1 1e-06 28.7 4.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CEP19792.1 - 0.0018 18.8 5.9 0.0018 18.8 5.9 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CEP19792.1 - 0.0063 16.5 0.4 0.0063 16.5 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 CEP19792.1 - 0.28 11.4 4.5 0.78 10.0 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CEP19792.1 - 0.49 10.6 14.0 0.35 11.1 9.5 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain HATPase_c PF02518.26 CEP19793.1 - 5.2e-25 88.1 0.2 1.4e-24 86.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 CEP19793.1 - 3.6e-22 78.4 0.1 2e-14 53.6 0.1 2.6 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 CEP19793.1 - 1e-18 67.1 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 CEP19793.1 - 2.6e-17 63.0 0.0 1.5e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 CEP19793.1 - 3.9e-16 59.3 0.0 3.5e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 CEP19793.1 - 5.6e-11 42.4 0.0 1e-07 31.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CEP19793.1 - 8.2e-11 42.1 0.0 6.2e-08 32.8 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 CEP19793.1 - 0.004 17.1 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain Aminotran_3 PF00202.21 CEP19794.1 - 2.5e-103 345.9 0.0 1.3e-101 340.2 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CEP19794.1 - 0.073 12.2 0.0 0.42 9.7 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Aldo_ket_red PF00248.21 CEP19795.1 - 2.4e-80 269.9 0.0 2.9e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 CEP19795.1 - 0.011 15.9 0.0 3 8.1 0.1 2.7 2 0 0 2 2 2 0 NAF domain Syd PF07348.12 CEP19797.1 - 0.014 15.0 3.6 0.034 13.8 3.6 1.6 1 0 0 1 1 1 0 Syd protein (SUKH-2) CBF PF03914.17 CEP19798.1 - 2.1e-30 106.0 2.5 2.1e-30 106.0 2.5 2.1 2 1 0 2 2 2 1 CBF/Mak21 family DUF3510 PF12022.8 CEP19798.1 - 0.89 10.0 5.7 0.25 11.8 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Velvet PF11754.8 CEP19799.1 - 5.9e-45 154.2 7.3 3.6e-33 115.6 1.2 4.8 2 2 1 3 3 3 2 Velvet factor MMR_HSR1 PF01926.23 CEP19800.1 - 2.9e-21 75.7 0.2 1e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP19800.1 - 1.4e-08 34.8 0.5 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CEP19800.1 - 1.2e-06 28.1 0.3 2e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 CEP19800.1 - 1.9e-05 24.3 0.4 3.1e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CEP19800.1 - 2.3e-05 24.0 1.6 0.00024 20.7 1.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CEP19800.1 - 4.6e-05 23.6 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CEP19800.1 - 0.00015 21.9 0.7 0.016 15.3 0.3 2.7 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 CEP19800.1 - 0.00059 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CEP19800.1 - 0.0013 18.1 2.7 0.38 10.0 2.7 2.7 1 1 0 1 1 1 1 Septin AIG1 PF04548.16 CEP19800.1 - 0.0064 15.9 1.3 0.011 15.1 0.0 1.8 2 1 0 2 2 2 1 AIG1 family LemA PF04011.12 CEP19800.1 - 0.0083 16.0 1.4 0.015 15.1 0.2 2.0 2 0 0 2 2 2 1 LemA family SRPRB PF09439.10 CEP19800.1 - 0.0084 15.6 0.0 0.024 14.1 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TrmE_N PF10396.9 CEP19801.1 - 7.3e-39 132.7 0.0 2.5e-38 131.0 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 CEP19801.1 - 3.5e-36 125.3 0.2 5.1e-36 124.8 0.2 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 CEP19801.1 - 2e-21 76.2 0.0 4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CEP19801.1 - 1.6e-09 37.5 0.2 1.7e-08 34.1 0.1 2.5 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CEP19801.1 - 6.6e-06 26.3 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 CEP19801.1 - 1.6e-05 24.9 0.2 0.0027 17.6 0.0 2.5 1 1 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 CEP19801.1 - 9e-05 21.6 1.1 0.16 10.9 0.2 3.2 2 1 1 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CEP19801.1 - 0.00063 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CEP19801.1 - 0.0022 18.2 0.0 0.1 12.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CEP19801.1 - 0.0025 18.3 0.0 0.0063 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CEP19801.1 - 0.0034 17.2 0.0 6.6 6.4 0.0 3.2 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CEP19801.1 - 0.0036 16.9 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 CEP19801.1 - 0.0049 16.5 0.1 1.1 8.9 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CEP19801.1 - 0.0053 17.3 0.1 0.011 16.3 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CEP19801.1 - 0.0093 16.2 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 CEP19801.1 - 0.019 14.4 0.1 0.067 12.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 CEP19801.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.6 CEP19801.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CEP19801.1 - 0.052 13.3 0.1 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CEP19801.1 - 0.09 12.2 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 CEP19801.1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_35 PF14516.6 CEP19801.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain 4HB_MCP_1 PF12729.7 CEP19802.1 - 0.058 12.9 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction WIF PF02019.18 CEP19803.1 - 0.066 12.9 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 WIF domain Aldo_ket_red PF00248.21 CEP19805.1 - 6e-32 111.0 0.8 6.3e-31 107.6 0.8 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family V-SNARE_C PF12352.8 CEP19806.1 - 0.0013 18.9 4.5 0.064 13.5 0.1 3.0 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.12 CEP19806.1 - 0.0078 16.7 0.8 0.0078 16.7 0.8 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 CEP19806.1 - 3.4 7.7 6.4 5.6 7.0 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Vip3A_N PF12495.8 CEP19806.1 - 5.8 6.8 7.8 6.2 6.7 3.7 2.6 2 1 0 2 2 2 0 Vegetative insecticide protein 3A N terminal RPN1_RPN2_N PF17781.1 CEP19807.1 - 3.3e-121 404.4 1.3 6e-121 403.6 1.3 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CEP19807.1 - 3.8e-32 110.1 0.1 7.1e-32 109.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CEP19807.1 - 6.5e-32 108.4 23.8 1.1e-06 28.8 0.1 8.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CEP19807.1 - 5.1e-05 23.6 0.0 0.25 11.8 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats Perilipin PF03036.16 CEP19807.1 - 0.43 9.6 5.2 0.73 8.8 5.2 1.3 1 0 0 1 1 1 0 Perilipin family CDC45 PF02724.14 CEP19807.1 - 0.75 8.0 6.2 1.1 7.5 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Drf_GBD PF06371.13 CEP19807.1 - 2.2 7.8 7.7 4.5 6.8 7.7 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Pinin_SDK_memA PF04696.13 CEP19807.1 - 2.3 8.3 17.9 5.9 7.0 17.9 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4175 PF13779.6 CEP19807.1 - 2.4 6.0 8.2 3.5 5.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CCDC-167 PF15188.6 CEP19807.1 - 4.2 7.8 11.0 14 6.1 11.0 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Glyco_transf_15 PF01793.16 CEP19808.1 - 2.3e-203 674.5 21.1 4.4e-113 377.8 4.4 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 CEP19808.1 - 0.23 11.7 5.7 1.2 9.5 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) VID27 PF08553.10 CEP19809.1 - 4.3e-61 207.0 0.3 3.2e-60 204.1 0.3 2.0 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 CEP19809.1 - 3.9e-16 59.3 1.4 5.5e-16 58.8 0.1 2.0 2 0 0 2 2 2 1 VID27 PH-like domain VID27_N PF17748.1 CEP19809.1 - 1.1e-09 38.3 2.4 5.7e-08 32.8 0.2 2.5 2 0 0 2 2 2 2 VID27 N-terminal region CaM-KIIN PF15170.6 CEP19809.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor Evr1_Alr PF04777.13 CEP19810.1 - 3.4e-21 75.6 0.3 8.3e-21 74.3 0.3 1.7 1 0 0 1 1 1 1 Erv1 / Alr family DUF973 PF06157.11 CEP19810.1 - 0.0015 17.6 0.3 0.0022 17.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) PspB PF06667.12 CEP19810.1 - 0.041 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B Ank_2 PF12796.7 CEP19811.1 - 1.7e-24 86.2 1.3 5.9e-13 49.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CEP19811.1 - 1.3e-18 67.1 5.0 2.9e-06 27.7 0.8 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CEP19811.1 - 3.1e-13 49.5 3.4 0.038 14.5 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CEP19811.1 - 2.1e-12 46.1 0.9 0.21 12.2 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CEP19811.1 - 7.7e-08 32.5 8.3 0.0049 17.1 0.0 5.5 1 1 4 5 5 5 3 Ankyrin repeats (many copies) TFCD_C PF12612.8 CEP19812.1 - 7.2e-51 172.7 0.8 3.1e-49 167.4 0.0 3.5 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal DUF2431 PF10354.9 CEP19812.1 - 9.4e-50 169.2 0.0 5.1e-49 166.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) HEAT PF02985.22 CEP19812.1 - 1.3e-05 25.0 4.6 0.009 16.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 CEP19812.1 - 0.00032 21.1 1.6 1.3 9.6 0.0 5.4 5 1 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 CEP19812.1 - 0.00045 20.5 0.6 1.4 9.4 0.0 4.6 4 1 1 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CEP19812.1 - 0.00079 20.0 0.1 4.2 8.1 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Kinesin PF00225.23 CEP19813.1 - 8.7e-92 307.6 0.2 8.7e-92 307.6 0.2 2.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CEP19813.1 - 9.1e-12 45.2 0.0 9.1e-12 45.2 0.0 3.5 2 2 0 2 2 2 1 Microtubule binding DUF4710 PF15828.5 CEP19813.1 - 0.0026 17.8 1.5 0.0026 17.8 1.5 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4710) Aa_trans PF01490.18 CEP19815.1 - 1.4e-55 188.7 27.2 1.6e-54 185.2 27.2 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CEP19815.1 - 6.6e-08 31.8 29.4 2.7e-07 29.8 29.4 1.8 1 1 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 CEP19815.1 - 0.0026 16.1 6.5 0.0026 16.1 6.5 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2070) DUF5305 PF17231.2 CEP19815.1 - 1.7 8.0 3.8 12 5.2 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5305) CcmD PF04995.14 CEP19815.1 - 2.1 8.5 8.4 33 4.6 0.2 3.6 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RT_RNaseH PF17917.1 CEP19816.1 - 2.6e-33 114.5 0.0 6.2e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP19816.1 - 2e-31 108.0 0.2 5.1e-31 106.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CEP19816.1 - 1.3e-27 96.8 0.1 2.9e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP19816.1 - 3.1e-20 72.0 0.1 1.1e-19 70.3 0.1 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CEP19816.1 - 1.2e-15 57.7 0.0 5.5e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 CEP19816.1 - 9.9e-13 47.8 0.8 2.5e-12 46.5 0.8 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP19816.1 - 2.8e-05 24.2 0.0 6.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PAPA-1 PF04795.12 CEP19818.1 - 0.11 13.3 4.2 0.17 12.7 4.3 1.3 1 1 0 1 1 1 0 PAPA-1-like conserved region HTH_28 PF13518.6 CEP19819.1 - 2.9e-05 24.1 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CEP19819.1 - 0.0004 20.1 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP19819.1 - 0.0021 18.0 0.1 0.0031 17.5 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.20 CEP19819.1 - 0.0047 17.2 0.0 0.0054 17.0 0.0 1.2 1 0 0 1 1 1 1 Transposase BrkDBD PF09607.10 CEP19819.1 - 0.0086 15.8 0.7 0.016 15.0 0.4 1.6 1 1 0 1 1 1 1 Brinker DNA-binding domain HTH_17 PF12728.7 CEP19819.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 CEP19819.1 - 0.017 15.7 0.1 0.022 15.3 0.1 1.2 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Sigma70_r4_2 PF08281.12 CEP19819.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CEP19819.1 - 0.026 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 CEP19819.1 - 0.029 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain YdaS_antitoxin PF15943.5 CEP19819.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_1 PF00126.27 CEP19819.1 - 0.093 12.7 0.1 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family YjfB_motility PF14070.6 CEP19820.1 - 0.011 15.9 0.4 0.019 15.1 0.4 1.4 1 0 0 1 1 1 0 Putative motility protein Malate_DH PF12434.8 CEP19820.1 - 0.13 12.3 1.0 0.13 12.3 1.0 1.7 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Presenilin PF01080.17 CEP19820.1 - 5.9 5.5 6.2 6.1 5.5 6.2 1.0 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 CEP19821.1 - 0.011 14.0 39.1 0.014 13.7 39.1 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 CEP19821.1 - 0.37 10.4 31.5 0.49 10.1 31.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 CEP19821.1 - 0.98 8.8 40.7 1.4 8.3 40.7 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 CEP19821.1 - 2.2 6.9 19.5 2.6 6.7 19.5 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 CEP19821.1 - 2.3 7.4 47.8 2.9 7.2 47.8 1.0 1 0 0 1 1 1 0 BUD22 ORC6 PF05460.13 CEP19821.1 - 2.4 7.3 21.3 3.3 6.9 21.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SAGA-Tad1 PF12767.7 CEP19821.1 - 4.3 7.0 13.9 5.9 6.6 13.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CNDH2_C PF16858.5 CEP19821.1 - 4.6 7.0 20.8 6 6.6 20.8 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Hamartin PF04388.12 CEP19821.1 - 5.6 5.5 16.2 6.3 5.3 16.2 1.0 1 0 0 1 1 1 0 Hamartin protein IDO PF01231.18 CEP19822.1 - 2.7 6.7 5.7 0.53 9.0 0.1 1.9 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase DDHD PF02862.17 CEP19823.1 - 3.2 7.9 8.5 3.4 7.8 8.5 1.0 1 0 0 1 1 1 0 DDHD domain DUF3043 PF11241.8 CEP19823.1 - 7.1 6.6 8.7 8.7 6.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TERB2 PF15101.6 CEP19823.1 - 7.8 6.5 9.8 8.3 6.4 9.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 AAA_32 PF13654.6 CEP19824.1 - 0.0061 15.4 4.1 0.0074 15.1 4.1 1.2 1 0 0 1 1 1 1 AAA domain DUF1631 PF07793.11 CEP19824.1 - 0.15 10.4 5.9 0.18 10.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) BORCS6 PF10157.9 CEP19824.1 - 0.83 9.9 5.8 0.88 9.8 4.2 1.7 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 MAJIN PF15077.6 CEP19824.1 - 6.1 6.6 9.6 1.2 8.9 2.2 2.3 2 1 0 2 2 2 0 Membrane-anchored junction protein DUF3659 PF12396.8 CEP19825.1 - 4.4e-93 305.2 47.8 3.4e-18 65.3 4.5 7.5 7 0 0 7 7 7 7 Protein of unknown function (DUF3659) DUF883 PF05957.13 CEP19825.1 - 0.01 16.4 10.0 0.01 16.4 10.0 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) RNB PF00773.19 CEP19826.1 - 1.1e-101 340.5 0.1 1.5e-101 340.0 0.1 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CEP19826.1 - 4.7e-20 71.4 0.0 1.6e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CEP19826.1 - 4.2e-13 49.3 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CEP19826.1 - 1.6e-11 44.0 0.1 4.4e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 S1 domain PIN_4 PF13638.6 CEP19826.1 - 3e-11 43.7 0.2 6.7e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CEP19826.1 - 2.4e-10 40.4 0.4 1.2e-06 28.6 0.0 4.3 2 1 1 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 CEP19826.1 - 0.017 15.4 0.1 0.053 13.8 0.1 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Homeodomain PF00046.29 CEP19827.1 - 1.4e-18 66.5 2.7 3e-18 65.4 2.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CEP19827.1 - 0.022 14.7 0.3 0.069 13.1 0.3 1.9 1 0 0 1 1 1 0 Homeobox KN domain Diphthamide_syn PF01866.17 CEP19828.1 - 6.6e-103 344.3 1.8 2e-58 198.3 0.1 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein RuBisCO_large PF00016.20 CEP19828.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain DDE_3 PF13358.6 CEP19829.1 - 9.1e-31 106.6 0.2 2.8e-28 98.5 0.1 3.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 CEP19829.1 - 0.0039 17.0 0.1 0.0096 15.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 CEP19829.1 - 0.046 13.7 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_17 PF12728.7 CEP19829.1 - 0.13 12.4 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-RVT PF13966.6 CEP19830.1 - 0.00074 20.2 0.5 0.002 18.8 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF445 PF04286.12 CEP19831.1 - 4.5 7.0 26.2 0.56 10.0 10.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DDE_3 PF13358.6 CEP19832.1 - 5.8e-07 29.4 0.0 8.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FHA PF00498.26 CEP19833.1 - 1.6e-13 50.8 0.0 3.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CEP19833.1 - 0.0073 16.6 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain C2 PF00168.30 CEP19834.1 - 1e-11 45.1 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain Carn_acyltransf PF00755.20 CEP19835.1 - 8.2e-180 599.3 0.0 9.9e-180 599.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ricin_B_lectin PF00652.22 CEP19838.1 - 1.4e-53 180.5 6.6 2.5e-07 31.0 0.0 11.9 9 3 3 12 12 12 12 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CEP19838.1 - 1.3e-35 122.0 35.7 1.6e-06 28.8 0.1 13.5 11 4 3 15 15 15 12 Ricin-type beta-trefoil lectin domain-like PurL_C PF16904.5 CEP19838.1 - 0.11 12.8 0.3 0.63 10.4 0.3 2.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus DUF1317 PF07026.11 CEP19838.1 - 0.18 11.7 1.8 2.2 8.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) OPA3 PF07047.12 CEP19839.1 - 7.2e-46 155.0 0.3 7.2e-46 155.0 0.3 1.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) FlxA PF14282.6 CEP19839.1 - 0.053 13.5 2.1 0.08 12.9 2.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Fibin PF15819.5 CEP19839.1 - 0.063 13.0 1.4 0.099 12.4 1.4 1.2 1 0 0 1 1 1 0 Fin bud initiation factor homologue NicO PF03824.16 CEP19839.1 - 0.099 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein KIAA1430 PF13879.6 CEP19839.1 - 0.24 12.2 6.6 0.54 11.0 6.1 1.8 1 1 1 2 2 2 0 KIAA1430 homologue bZIP_2 PF07716.15 CEP19839.1 - 0.71 10.0 9.7 3.2 7.9 0.6 2.4 1 1 1 2 2 2 0 Basic region leucine zipper HisKA PF00512.25 CEP19839.1 - 1 9.4 4.4 4.6 7.4 4.4 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain NYD-SP28_assoc PF14775.6 CEP19839.1 - 1.9 8.7 9.6 9.7 6.4 3.3 2.4 1 1 0 2 2 2 0 Sperm tail C-terminal domain GATase_6 PF13522.6 CEP19840.1 - 7.1e-17 61.9 0.0 1.6e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CEP19840.1 - 9.3e-13 48.2 0.0 2.4e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CEP19840.1 - 5.6e-07 28.7 0.0 9.9e-07 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 CEP19840.1 - 8.4e-07 28.6 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HEPN_AbiU2 PF18734.1 CEP19840.1 - 0.099 12.1 2.0 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 AbiU2 zf-C2H2_6 PF13912.6 CEP19841.1 - 0.055 13.5 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DivIC PF04977.15 CEP19842.1 - 0.23 11.3 1.4 0.54 10.1 1.4 1.6 1 1 0 1 1 1 0 Septum formation initiator Borrelia_orfA PF02414.15 CEP19843.1 - 0.31 10.6 2.9 0.42 10.2 2.9 1.3 1 0 0 1 1 1 0 Borrelia ORF-A KCH PF16944.5 CEP19849.1 - 3.2e-80 269.5 10.0 4.1e-80 269.2 10.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF5526 PF17664.1 CEP19849.1 - 3.5 7.2 6.0 0.29 10.7 1.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5526) zf-rbx1 PF12678.7 CEP19850.1 - 2e-11 44.0 6.4 2e-11 44.0 6.4 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CEP19850.1 - 3.1e-10 40.2 8.5 5e-10 39.6 3.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CEP19850.1 - 3.9e-08 33.2 0.8 1.8e-07 31.1 0.8 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CEP19850.1 - 5.1e-08 32.7 2.9 1.8e-07 30.9 2.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CEP19850.1 - 4.5e-06 26.4 5.1 0.00018 21.3 1.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CEP19850.1 - 7.8e-06 25.6 5.3 7.8e-06 25.6 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Suf PF05843.14 CEP19850.1 - 5.8e-05 23.2 8.1 5.8e-05 23.2 8.1 2.1 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) zf-RING_5 PF14634.6 CEP19850.1 - 7.2e-05 22.7 4.9 0.00053 19.9 5.3 2.2 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CEP19850.1 - 0.00013 21.8 4.2 0.00028 20.7 1.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CEP19850.1 - 0.00013 21.9 5.4 0.00091 19.2 5.4 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CEP19850.1 - 0.00053 20.1 1.6 0.002 18.3 1.6 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CEP19850.1 - 0.00058 19.4 1.9 0.0014 18.2 1.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CEP19850.1 - 0.00083 19.1 1.1 0.00083 19.1 1.1 2.9 2 0 0 2 2 2 1 RING-like zinc finger Rtf2 PF04641.12 CEP19850.1 - 0.0036 16.7 4.3 0.0036 16.7 4.3 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger Plasmodium_Vir PF05795.11 CEP19850.1 - 0.042 13.3 4.9 0.091 12.2 4.9 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-RING-like PF08746.11 CEP19850.1 - 0.21 11.9 3.9 0.54 10.6 3.9 1.7 1 0 0 1 1 1 0 RING-like domain EOS1 PF12326.8 CEP19850.1 - 0.66 9.9 4.8 0.34 10.8 0.5 2.3 2 0 0 2 2 2 0 N-glycosylation protein zf-RING_4 PF14570.6 CEP19850.1 - 0.8 9.6 4.8 0.77 9.6 1.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CEP19850.1 - 2.4 8.4 8.0 0.84 9.9 4.2 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain RR_TM4-6 PF06459.12 CEP19850.1 - 4.8 6.9 16.7 0.5 10.2 8.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 CEP19850.1 - 4.9 6.0 38.3 0.14 11.1 27.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 CEP19850.1 - 6.3 7.0 15.2 0.29 11.3 5.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Endostatin PF06482.11 CEP19850.1 - 7.4 5.9 21.4 0.087 12.3 11.5 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin 3HCDH_N PF02737.18 CEP19851.1 - 8.2e-60 201.8 4.5 1.1e-59 201.4 4.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CEP19851.1 - 1.1e-33 115.6 0.0 3.3e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 CEP19851.1 - 0.037 14.0 0.8 0.072 13.1 0.6 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 CEP19851.1 - 0.052 13.8 0.3 0.11 12.8 0.3 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CEP19851.1 - 0.056 12.8 0.3 0.098 12.0 0.3 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S64 PF08192.11 CEP19851.1 - 0.066 11.7 0.3 0.09 11.3 0.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_4 PF02056.16 CEP19851.1 - 0.082 12.4 1.3 0.38 10.3 1.2 2.2 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase NAD_binding_2 PF03446.15 CEP19851.1 - 0.15 12.2 3.7 0.72 10.0 3.7 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_1 PF00076.22 CEP19852.1 - 4.4e-22 77.7 0.0 1.3e-09 37.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CEP19852.1 - 1.5e-17 62.2 0.3 3.2e-05 23.3 0.0 6.0 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 CEP19852.1 - 1.8e-06 27.7 0.0 0.039 13.8 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 CEP19852.1 - 3.7e-06 26.9 0.1 0.044 13.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_5 PF13893.6 CEP19852.1 - 0.011 15.3 0.0 0.064 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CEP19852.1 - 0.012 15.6 0.0 2.2 8.4 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Pkinase PF00069.25 CEP19853.1 - 2.3e-70 237.0 0.0 3.5e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19853.1 - 2e-47 161.6 0.3 1e-46 159.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP19853.1 - 4.7e-09 35.5 0.0 1.3e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CEP19853.1 - 9e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 CEP19853.1 - 0.00089 19.6 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Haspin_kinase PF12330.8 CEP19853.1 - 0.0012 17.9 0.3 0.0034 16.4 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CEP19853.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP19853.1 - 0.0068 16.4 0.0 0.15 12.0 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CEP19853.1 - 0.4 10.3 2.8 0.29 10.7 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short PF00106.25 CEP19854.1 - 5.7e-17 61.8 0.0 3.1e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CEP19854.1 - 7.5e-08 32.2 0.0 0.0073 15.9 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CEP19854.1 - 4.2e-05 23.5 0.0 9.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CEP19854.1 - 0.021 14.3 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CEP19854.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_4 PF07993.12 CEP19854.1 - 0.18 10.9 0.0 4.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein CPSF73-100_C PF11718.8 CEP19855.1 - 0.064 12.8 2.2 0.1 12.1 1.5 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MIF4G PF02854.19 CEP19856.1 - 1.9e-28 99.6 3.2 1.9e-28 99.6 3.2 2.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CEP19856.1 - 1.7e-12 47.3 0.3 3.1e-11 43.3 0.1 3.1 2 1 0 2 2 2 1 MA3 domain C_Hendra PF16821.5 CEP19856.1 - 0.32 10.9 10.6 0.041 13.8 5.1 2.5 2 0 0 2 2 2 0 C protein from hendra and measles viruses Glyco_hydro_18 PF00704.28 CEP19857.1 - 2e-20 73.8 3.3 2e-20 73.8 3.3 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 Mucin PF01456.17 CEP19857.1 - 1.7 8.6 20.6 3.4 7.6 20.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Trehalose_PPase PF02358.16 CEP19858.1 - 3e-58 196.7 0.0 3.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.16 CEP19859.1 - 4.5e-49 167.2 41.3 4.5e-49 167.2 41.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP19859.1 - 5e-16 58.6 11.2 5e-16 58.6 11.2 2.8 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CEP19859.1 - 6.3e-12 44.7 20.9 2.3e-11 42.9 20.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2951 PF11166.8 CEP19859.1 - 0.19 11.9 1.0 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Wzz PF02706.15 CEP19859.1 - 5.6 7.3 12.5 7.7 6.9 0.6 4.0 4 0 0 4 4 4 0 Chain length determinant protein GCN5L1 PF06320.13 CEP19860.1 - 1.2e-38 131.8 9.7 1.3e-38 131.6 9.7 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Pox_polyA_pol_C PF12629.7 CEP19860.1 - 0.0037 17.1 1.2 0.0044 16.9 1.2 1.2 1 0 0 1 1 1 1 Poxvirus poly(A) polymerase C-terminal domain Atg14 PF10186.9 CEP19860.1 - 0.027 13.6 4.1 0.029 13.4 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phycobilisome PF00502.19 CEP19860.1 - 0.03 14.3 0.6 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 Phycobilisome protein Apolipoprotein PF01442.18 CEP19860.1 - 0.038 13.9 4.2 0.055 13.3 4.1 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoO PF09769.9 CEP19860.1 - 0.12 12.3 0.8 0.45 10.5 0.1 1.9 1 1 1 2 2 2 0 Apolipoprotein O AF0941-like PF14591.6 CEP19860.1 - 0.15 12.6 2.7 2.3 8.8 0.1 2.2 1 1 1 2 2 2 0 AF0941-like NusB PF01029.18 CEP19860.1 - 0.16 12.2 2.8 0.23 11.7 2.8 1.2 1 0 0 1 1 1 0 NusB family Tweety PF04906.13 CEP19860.1 - 0.17 10.5 3.8 0.18 10.4 3.8 1.1 1 0 0 1 1 1 0 Tweety Spectrin PF00435.21 CEP19860.1 - 0.29 11.6 10.8 0.29 11.6 7.5 2.0 1 1 1 2 2 2 0 Spectrin repeat Synaptobrevin PF00957.21 CEP19860.1 - 0.75 9.6 5.6 0.25 11.1 1.9 2.1 1 1 1 2 2 2 0 Synaptobrevin DUF3450 PF11932.8 CEP19860.1 - 0.98 8.7 8.9 0.2 10.9 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 CEP19860.1 - 2 7.2 5.9 2 7.2 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Nas2_N PF18265.1 CEP19860.1 - 3.4 7.7 6.9 2 8.4 0.5 2.8 2 1 0 2 2 2 0 Nas2 N_terminal domain AI-2E_transport PF01594.16 CEP19860.1 - 9.2 5.3 5.6 17 4.4 0.6 2.0 1 1 1 2 2 2 0 AI-2E family transporter LAG1-DNAbind PF09271.11 CEP19861.1 - 2.9e-42 144.9 7.1 2.9e-42 144.9 7.1 4.3 4 2 0 4 4 4 1 LAG1, DNA binding BTD PF09270.10 CEP19861.1 - 3.8e-22 79.2 0.1 1.7e-16 60.8 0.0 3.8 3 1 0 3 3 3 2 Beta-trefoil DNA-binding domain TIG PF01833.24 CEP19861.1 - 0.00037 20.5 0.0 0.0015 18.5 0.0 2.1 1 0 0 1 1 1 1 IPT/TIG domain HlyU PF10115.9 CEP19862.1 - 0.079 13.0 1.7 0.26 11.4 0.1 2.5 3 0 0 3 3 3 0 Transcriptional activator HlyU HSP70 PF00012.20 CEP19863.1 - 9.8e-265 879.4 12.0 1.1e-264 879.2 12.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CEP19863.1 - 4.9e-15 55.2 2.7 2.9e-12 46.1 0.5 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CEP19863.1 - 0.00041 20.1 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CEP19863.1 - 0.029 14.8 10.7 1.6 9.2 0.1 4.3 3 2 0 3 3 3 0 Cell division protein FtsA SAM_DrpA PF18255.1 CEP19863.1 - 0.12 12.6 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain DUF5486 PF17588.2 CEP19863.1 - 0.32 10.9 2.6 7 6.6 1.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Phlebovirus_NSM PF07246.11 CEP19863.1 - 0.8 9.0 6.9 1.5 8.1 6.9 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ribosomal_L12 PF00542.19 CEP19863.1 - 1.1 9.6 6.5 0.21 11.9 1.9 2.2 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain YkyA PF10368.9 CEP19863.1 - 1.4 8.6 14.2 0.43 10.2 11.1 1.6 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein rve PF00665.26 CEP19866.1 - 1.6e-05 25.1 0.0 0.00019 21.6 0.0 2.2 1 1 1 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 CEP19866.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.6 CEP19869.1 - 1.3e-10 41.2 0.1 1.6e-05 24.7 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 CEP19873.1 - 6.9e-07 29.2 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP19873.1 - 0.0062 16.8 0.2 0.026 14.8 0.2 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pepsin-I3 PF06394.13 CEP19873.1 - 0.021 15.0 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Peptidase_M13_N PF05649.13 CEP19874.1 - 1.2e-104 351.1 0.0 1.6e-104 350.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CEP19874.1 - 2.9e-70 236.0 0.1 4.2e-70 235.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M13 HLH PF00010.26 CEP19875.1 - 3.1e-11 43.1 0.9 8.1e-11 41.7 0.9 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aspzincin_M35 PF14521.6 CEP19876.1 - 0.11 13.1 6.1 1.1 9.7 0.1 3.2 3 0 0 3 3 3 0 Lysine-specific metallo-endopeptidase Ribosomal_L50 PF10501.9 CEP19877.1 - 2.2e-11 43.9 1.0 3.3e-11 43.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S WD40 PF00400.32 CEP19878.1 - 9.2e-41 137.1 14.1 2.3e-05 25.1 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19878.1 - 4.7e-12 46.1 1.4 0.012 15.9 0.0 5.4 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PH PF00169.29 CEP19878.1 - 0.00051 20.5 1.8 0.0016 19.0 1.8 1.8 1 0 0 1 1 1 1 PH domain Ge1_WD40 PF16529.5 CEP19878.1 - 0.00059 18.9 0.6 0.099 11.6 0.0 3.5 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CEP19878.1 - 0.00088 18.7 0.6 0.0017 17.8 0.1 1.8 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CEP19878.1 - 0.0025 16.4 0.2 0.0081 14.7 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 CEP19878.1 - 0.019 13.6 9.1 0.11 11.1 0.1 4.5 3 1 2 6 6 6 0 Nucleoporin Nup120/160 Pkinase PF00069.25 CEP19879.1 - 2.4e-46 158.2 0.0 4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19879.1 - 7.2e-25 87.7 0.0 1.5e-24 86.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19879.1 - 0.0014 18.1 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 CEP19879.1 - 0.019 14.0 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 CEP19879.1 - 0.05 12.5 0.1 0.088 11.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CEP19879.1 - 0.055 13.1 0.1 13 5.4 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Porin_4 PF13609.6 CEP19879.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin MUG113 PF13455.6 CEP19879.1 - 0.5 11.1 0.0 0.5 11.1 0.0 2.2 3 0 0 3 3 3 0 Meiotically up-regulated gene 113 Hist_deacetyl PF00850.19 CEP19880.1 - 9.7e-82 274.9 0.0 2.2e-81 273.7 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Far-17a_AIG1 PF04750.14 CEP19880.1 - 1.7e-15 56.9 7.6 2.6e-15 56.3 7.6 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SOG2 PF10428.9 CEP19880.1 - 9.2 5.3 19.3 13 4.8 19.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Aldedh PF00171.22 CEP19881.1 - 4.8e-88 295.7 0.0 5.7e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gluconate_2-dh3 PF13618.6 CEP19881.1 - 0.011 15.9 0.1 0.14 12.4 0.0 2.5 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 HAT PF02184.16 CEP19882.1 - 1e-21 76.6 66.4 4.4e-15 55.3 3.3 13.7 15 1 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CEP19882.1 - 4.7e-19 67.5 13.8 0.008 16.9 0.1 9.6 9 2 3 12 12 10 4 Tetratricopeptide repeat Suf PF05843.14 CEP19882.1 - 2.4e-17 63.9 27.7 1.8e-05 24.9 0.5 7.0 3 1 4 7 7 7 6 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CEP19882.1 - 5.1e-17 62.1 0.0 0.024 15.1 0.0 6.8 3 2 4 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 CEP19882.1 - 2.8e-10 39.8 1.4 0.0011 19.2 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CEP19882.1 - 2.8e-06 26.7 10.6 0.1 11.8 0.3 4.5 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CEP19882.1 - 0.00021 21.2 7.6 20 5.6 0.0 8.1 10 0 0 10 10 10 0 Tetratricopeptide repeat BSD PF03909.17 CEP19882.1 - 0.00029 20.8 0.7 0.04 13.9 0.2 3.2 2 0 0 2 2 2 1 BSD domain TPR_16 PF13432.6 CEP19882.1 - 0.0013 19.3 1.0 15 6.4 0.1 4.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19882.1 - 0.0068 16.5 1.2 26 5.4 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CEP19882.1 - 0.008 16.2 25.5 0.27 11.2 3.5 6.7 5 1 0 5 5 5 3 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 CEP19882.1 - 0.0084 16.7 11.2 0.94 10.3 0.0 7.5 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CEP19882.1 - 0.071 13.3 2.2 18 5.5 0.0 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.21 CEP19883.1 - 2.1e-24 85.0 1.3 1.3e-23 82.4 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e peroxidase PF00141.23 CEP19885.1 - 2.5e-42 145.1 0.0 3.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ATP_transf PF09830.9 CEP19887.1 - 1.9e-23 82.4 0.0 3.5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CEP19887.1 - 5.5e-06 25.9 0.1 1.8e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 CEP19887.1 - 6.1e-05 23.7 0.1 0.0002 22.0 0.0 1.9 2 0 0 2 2 2 1 HIT domain DUF4922 PF16269.5 CEP19887.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) HHH_4 PF14490.6 CEP19887.1 - 0.12 12.4 0.1 0.58 10.2 0.0 2.1 3 0 0 3 3 3 0 Helix-hairpin-helix containing domain HTH_Tnp_Tc3_2 PF01498.18 CEP19889.1 - 1.1e-08 35.1 0.0 4.2e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Transposase ACT_3 PF10000.9 CEP19889.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 ACT domain ABC_tran_CTD PF16326.5 CEP19890.1 - 0.2 11.9 0.4 0.82 10.0 0.4 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain KH_1 PF00013.29 CEP19891.1 - 1.1e-20 73.3 6.1 1.3e-05 25.0 0.0 7.8 8 0 0 8 8 8 3 KH domain UPF0302 PF08864.10 CEP19891.1 - 0.027 14.5 1.2 0.26 11.4 1.1 2.5 2 0 0 2 2 2 0 UPF0302 domain SLS PF14611.6 CEP19891.1 - 0.039 13.8 0.2 0.039 13.8 0.2 4.1 3 1 2 5 5 5 0 Mitochondrial inner-membrane-bound regulator DUF2183 PF09949.9 CEP19894.1 - 4.4e-32 110.4 1.0 1e-31 109.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF4201 PF13870.6 CEP19894.1 - 3.9e-05 23.5 14.9 3.9e-05 23.5 14.9 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4201) Lectin_N PF03954.14 CEP19894.1 - 4.1 7.2 12.2 2 8.2 6.1 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain M PF02370.16 CEP19894.1 - 4.2 8.2 10.3 1.6e+02 3.4 0.1 5.4 2 1 2 4 4 4 0 M protein repeat Pkinase PF00069.25 CEP19895.1 - 9.3e-75 251.4 0.0 1.6e-74 250.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19895.1 - 1.7e-40 138.9 0.0 3.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CEP19895.1 - 5.8e-05 23.1 0.0 0.001 19.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CEP19895.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CEP19895.1 - 0.019 13.9 0.0 0.019 13.9 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CEP19895.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CEP19895.1 - 0.061 12.9 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CEP19895.1 - 0.099 12.2 0.0 0.099 12.2 0.0 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase Lamprin PF06403.11 CEP19897.1 - 0.027 14.4 0.5 0.06 13.3 0.2 1.7 2 0 0 2 2 2 0 Lamprin Kinesin PF00225.23 CEP19898.1 - 3e-107 358.4 0.5 3e-107 358.4 0.5 2.3 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CEP19898.1 - 2.9e-20 72.7 0.0 2.9e-20 72.7 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding DUF465 PF04325.13 CEP19898.1 - 0.00011 22.2 6.2 0.00011 22.2 6.2 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF465) TFA2_Winged_2 PF18121.1 CEP19898.1 - 8 6.2 9.5 1.3 8.8 1.4 4.0 5 1 0 5 5 5 0 TFA2 Winged helix domain 2 Dymeclin PF09742.9 CEP19899.1 - 4.4e-96 322.7 27.7 3.1e-92 310.0 19.9 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CEP19899.1 - 1.1e-10 40.4 17.1 1.1e-10 40.4 17.1 2.1 2 1 1 3 3 3 1 High-temperature-induced dauer-formation protein Aminotran_1_2 PF00155.21 CEP19900.1 - 4.1e-83 279.6 0.0 4.7e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NIF PF03031.18 CEP19902.1 - 1e-29 103.3 0.2 5.5e-29 101.0 0.1 2.1 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 CEP19902.1 - 1.3e-09 37.8 0.2 3.6e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 CEP19902.1 - 0.00036 20.8 0.1 0.0013 19.1 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CEP19902.1 - 0.003 17.9 0.0 0.0083 16.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cation_ATPase_C PF00689.21 CEP19903.1 - 1.1e-43 149.1 10.2 1.1e-43 149.1 10.2 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CEP19903.1 - 4.3e-41 140.4 1.4 4.3e-41 140.4 1.4 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CEP19903.1 - 9.4e-23 80.1 0.1 2.1e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CEP19903.1 - 2.8e-17 63.7 0.6 1.1e-16 61.7 0.6 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CEP19903.1 - 1.3e-11 44.0 0.0 3.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CEP19903.1 - 0.0021 17.9 0.3 0.0021 17.9 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 CEP19903.1 - 8.1 6.7 7.0 4.7 7.5 0.0 3.2 3 1 0 3 3 3 0 Anti-sigma-K factor rskA B12D PF06522.11 CEP19904.1 - 3e-21 75.0 0.0 3.9e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NPBW PF15180.6 CEP19904.1 - 0.018 14.9 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W Voltage_CLC PF00654.20 CEP19904.1 - 0.18 11.0 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel MFS_1 PF07690.16 CEP19906.1 - 2.5e-25 89.1 14.1 9.1e-21 74.2 0.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP19906.1 - 5.8e-14 51.8 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CEP19906.1 - 0.00092 17.8 0.1 0.0016 17.0 0.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CEP19906.1 - 0.032 13.1 1.9 0.072 11.9 0.1 2.1 2 0 0 2 2 2 0 MFS_1 like family Recep_L_domain PF01030.24 CEP19907.1 - 3.3e-10 40.1 6.0 0.00034 20.7 0.0 4.3 2 2 1 3 3 3 3 Receptor L domain FluMu_N PF17891.1 CEP19907.1 - 0.079 12.7 0.5 0.64 9.8 0.1 2.8 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain LRR_8 PF13855.6 CEP19907.1 - 9.6 6.1 7.1 3.4 7.5 0.1 3.3 4 0 0 4 4 4 0 Leucine rich repeat DDE_3 PF13358.6 CEP19910.1 - 1.6e-24 86.3 0.1 8.9e-18 64.4 0.1 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 CEP19910.1 - 0.00038 20.2 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DUF1804 PF08822.11 CEP19910.1 - 0.01 15.8 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) HTH_32 PF13565.6 CEP19910.1 - 0.023 15.3 0.0 0.058 14.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 CEP19910.1 - 0.097 12.8 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_1 PF00126.27 CEP19910.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family rve PF00665.26 CEP19913.1 - 9.8e-08 32.2 0.0 1.7e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CEP19913.1 - 0.00053 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1918 PF08940.11 CEP19913.1 - 0.06 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Kinesin PF00225.23 CEP19914.1 - 1.1e-75 254.6 0.7 1.5e-75 254.2 0.7 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CEP19914.1 - 5.6e-18 65.3 0.1 1.2e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding F-box-like PF12937.7 CEP19915.1 - 2.3e-06 27.4 0.3 2.3e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 F-box-like SLAIN PF15301.6 CEP19915.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 SLAIN motif-containing family LRR_4 PF12799.7 CEP19915.1 - 0.29 11.6 10.8 0.9 10.1 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) ribosomal_L24 PF17136.4 CEP19916.1 - 1.2e-09 38.4 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 CEP19917.1 - 1.4e-06 28.0 0.7 2.3e-06 27.3 0.7 1.4 1 0 0 1 1 1 1 KOW motif eIF3m_C_helix PF18005.1 CEP19917.1 - 0.078 12.7 0.1 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix DUF150_C PF17384.2 CEP19917.1 - 0.081 13.1 0.3 0.097 12.8 0.3 1.1 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LRR_8 PF13855.6 CEP19918.1 - 3.5e-26 90.7 18.9 8.6e-10 38.2 0.5 4.4 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CEP19918.1 - 1.2e-21 76.5 21.9 4.3e-05 23.8 3.9 4.7 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CEP19918.1 - 6.9e-07 29.0 26.5 1.2 9.9 0.5 9.2 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 CEP19918.1 - 0.00084 18.9 12.0 0.0078 15.7 1.0 2.7 1 1 2 3 3 3 3 Leucine-rich repeat CSTF_C PF14304.6 CEP19918.1 - 0.069 12.7 2.1 3.8 7.2 0.2 3.1 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 CEP19918.1 - 0.29 11.3 26.6 5.8 7.2 1.9 7.1 7 0 0 7 7 7 0 Leucine Rich repeat DDE_3 PF13358.6 CEP19919.1 - 4.2e-24 85.0 0.0 6.7e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 CEP19920.1 - 4e-14 52.6 0.0 6.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP19920.1 - 0.0035 17.9 0.0 0.0081 16.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain ADH_N_assoc PF13823.6 CEP19920.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated LRR_12 PF18837.1 CEP19921.1 - 0.0037 16.9 0.4 1 9.1 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat TPP_enzyme_C PF02775.21 CEP19922.1 - 1.5e-10 41.0 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF775 PF05603.12 CEP19923.1 - 0.062 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Hist_deacetyl PF00850.19 CEP19924.1 - 3.9e-48 164.5 0.0 3.3e-45 154.9 0.0 2.4 1 1 1 2 2 2 2 Histone deacetylase domain Tudor-knot PF11717.8 CEP19924.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ABC2_membrane PF01061.24 CEP19925.1 - 1.3e-38 132.5 24.3 1.3e-38 132.5 24.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CEP19925.1 - 3.2e-29 102.2 0.8 4.7e-29 101.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 CEP19925.1 - 5.3e-07 29.7 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 CEP19925.1 - 0.00072 19.5 0.0 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 CEP19925.1 - 0.00083 18.9 0.0 0.064 12.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CEP19925.1 - 0.0011 18.7 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CEP19925.1 - 0.0017 17.5 26.9 0.005 16.0 26.0 2.1 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CEP19925.1 - 0.0026 17.7 0.1 0.0083 16.0 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CEP19925.1 - 0.0028 18.1 0.2 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CEP19925.1 - 0.004 17.6 0.1 0.12 12.8 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CEP19925.1 - 0.0047 17.5 0.3 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CEP19925.1 - 0.0077 16.5 0.5 0.023 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 CEP19925.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CEP19925.1 - 0.024 15.1 0.1 0.057 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CEP19925.1 - 0.026 14.8 0.3 0.079 13.2 0.3 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CEP19925.1 - 0.037 13.9 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_35 PF14516.6 CEP19925.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 CEP19925.1 - 0.079 12.7 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CEP19925.1 - 0.12 12.6 0.7 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CEP19925.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 CEP19925.1 - 0.12 12.0 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CEP19925.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CEP19925.1 - 0.18 11.4 0.1 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CEP19925.1 - 0.92 8.7 16.5 0.094 12.0 11.1 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein zf-met PF12874.7 CEP19926.1 - 7.4e-11 42.1 99.6 0.019 15.3 0.4 12.3 12 0 0 12 12 12 8 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP19926.1 - 1.3e-08 34.9 96.9 0.0034 17.6 2.2 11.7 11 0 0 11 11 11 7 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CEP19926.1 - 1.7e-05 25.3 135.3 0.0055 17.4 3.1 13.4 13 0 0 13 13 13 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CEP19926.1 - 0.00069 19.9 10.9 0.0028 18.0 2.7 12.8 13 0 0 13 13 13 4 Zinc finger, C2H2 type DUF4251 PF14059.6 CEP19926.1 - 1.5 8.8 5.0 1.2 9.1 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Rad50_zn_hook PF04423.14 CEP19926.1 - 1.5 8.7 8.7 3.2 7.7 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif EthD PF07110.11 CEP19926.1 - 2.3 9.4 8.1 49 5.2 3.4 4.0 4 2 0 4 4 4 0 EthD domain Ribosomal_L18 PF17135.4 CEP19927.1 - 1.6e-88 295.0 5.1 1.7e-88 294.9 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CEP19927.1 - 0.00086 20.0 0.3 0.0023 18.6 0.3 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A IATP PF04568.12 CEP19928.1 - 0.00023 21.5 3.2 0.00028 21.2 3.2 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YABBY PF04690.13 CEP19928.1 - 0.033 14.7 1.2 0.038 14.6 1.2 1.1 1 0 0 1 1 1 0 YABBY protein PRELI PF04707.14 CEP19929.1 - 0.035 13.9 1.3 0.05 13.4 0.2 1.8 2 0 0 2 2 2 0 PRELI-like family RVT_1 PF00078.27 CEP19930.1 - 2.1e-43 148.4 0.1 4.6e-43 147.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP19930.1 - 6e-09 36.5 0.9 6e-09 36.5 0.9 2.8 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CEP19930.1 - 0.01 15.4 0.1 0.031 13.8 0.1 1.8 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Wza_C PF18412.1 CEP19930.1 - 0.27 11.0 1.1 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain HNH PF01844.23 CEP19930.1 - 2.4 8.4 6.8 4.3 7.6 0.1 3.5 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_10 PF16588.5 CEP19930.1 - 2.7 7.8 12.2 1.2 8.9 2.0 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 CEP19930.1 - 3.6 7.6 15.4 0.035 14.1 3.2 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 CEP19930.1 - 5.8 7.2 15.0 0.035 14.2 2.8 2.7 2 0 0 2 2 2 0 Zinc knuckle JAB PF01398.21 CEP19931.1 - 4.9e-15 55.5 0.0 1.6e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-C2H2 PF00096.26 CEP19932.1 - 2.7e-15 55.9 25.4 0.0001 22.5 1.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP19932.1 - 2.5e-12 46.6 29.1 2.2e-06 27.8 0.5 5.5 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP19932.1 - 1.5e-06 28.5 28.2 0.0013 19.4 1.6 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 CEP19932.1 - 0.00018 22.0 14.1 0.013 16.1 0.1 3.5 3 1 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CEP19932.1 - 0.0033 17.7 6.2 0.45 10.9 0.1 3.5 1 1 3 4 4 4 2 C2H2-type zinc ribbon zf-met PF12874.7 CEP19932.1 - 0.02 15.3 4.0 8.1 7.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CEP19932.1 - 0.038 14.3 4.1 17 5.8 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FCP1_C PF09309.10 CEP19932.1 - 0.052 13.4 4.9 0.085 12.7 4.9 1.3 1 0 0 1 1 1 0 FCP1, C-terminal DUF4692 PF15763.5 CEP19932.1 - 2.4 8.6 7.6 0.23 11.9 3.3 1.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF3591 PF12157.8 CEP19933.1 - 2.6e-176 586.6 0.0 2.6e-176 586.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CEP19933.1 - 3.4e-06 26.8 0.7 8.7e-06 25.5 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CEP19933.1 - 0.3 11.2 2.9 0.58 10.3 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Bin3 PF06859.12 CEP19934.1 - 8.3e-34 116.5 0.1 2.5e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 CEP19934.1 - 6.6e-12 45.5 0.2 5.8e-07 29.4 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CEP19934.1 - 2.1e-11 43.9 0.0 3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP19934.1 - 4.8e-10 40.0 0.0 4.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CEP19934.1 - 1.7e-09 38.3 0.0 0.0006 20.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CEP19934.1 - 2.5e-06 27.2 0.0 6.1e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CEP19934.1 - 3.7e-06 27.5 0.0 0.15 12.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 CEP19934.1 - 1.9e-05 24.2 0.6 3.8e-05 23.2 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CEP19934.1 - 1.9e-05 24.7 0.3 3.2e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CEP19934.1 - 0.0014 17.9 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 CEP19934.1 - 0.0083 15.6 0.0 0.023 14.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.12 CEP19934.1 - 0.0099 15.4 0.0 0.048 13.2 0.0 1.9 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MetW PF07021.12 CEP19934.1 - 0.028 14.0 0.0 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CEP19934.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CEP19934.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 CEP19934.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF3138 PF11336.8 CEP19934.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) rRNA_proc-arch PF13234.6 CEP19936.1 - 1.5e-80 271.0 0.2 3.5e-80 269.8 0.2 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CEP19936.1 - 1.2e-55 187.6 1.5 1.2e-55 187.6 1.5 2.1 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 CEP19936.1 - 5.4e-19 68.6 0.0 3e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CEP19936.1 - 1.4e-08 35.1 0.0 1.1e-07 32.1 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CEP19936.1 - 1.1e-05 25.5 0.0 6.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3450 PF11932.8 CEP19936.1 - 0.017 14.5 0.9 1.7 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) T2SSE PF00437.20 CEP19936.1 - 0.018 14.1 0.1 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 CEP19936.1 - 0.071 13.0 2.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MutS_V PF00488.21 CEP19937.1 - 1.2e-28 100.4 0.1 1.4e-28 100.2 0.1 1.0 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CEP19938.1 - 1.4e-21 77.6 3.2 2.1e-21 77.0 3.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CEP19938.1 - 4.1e-08 33.5 1.7 1.2e-07 32.0 1.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MSP1b PF03429.13 CEP19938.1 - 0.21 9.6 0.6 0.29 9.2 0.6 1.1 1 0 0 1 1 1 0 Major surface protein 1B WD40 PF00400.32 CEP19939.1 - 1.7e-29 101.4 0.2 5.1e-10 39.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CEP19939.1 - 1.8e-10 41.0 0.1 8.2e-05 22.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CEP19939.1 - 0.00024 21.1 0.0 0.3 10.9 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A bZIP_1 PF00170.21 CEP19939.1 - 0.00052 20.1 0.9 0.00097 19.2 0.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 CEP19939.1 - 0.022 14.5 0.7 0.042 13.6 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Nup160 PF11715.8 CEP19939.1 - 0.025 13.2 0.1 0.7 8.5 0.0 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 betaPIX_CC PF16523.5 CEP19939.1 - 0.038 13.8 1.4 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 betaPIX coiled coil Csm1_N PF18504.1 CEP19939.1 - 0.071 13.5 0.8 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain WD40_like PF17005.5 CEP19939.1 - 0.1 11.9 0.1 3 7.1 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 CEP19939.1 - 0.16 10.9 0.0 2.2 7.1 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Trehalase PF01204.18 CEP19940.1 - 3.8e-178 593.5 2.4 4.7e-178 593.2 2.4 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CEP19940.1 - 2.1e-14 52.9 0.2 4.6e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain CDC45 PF02724.14 CEP19941.1 - 9.3 4.4 10.1 15 3.7 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 CEP19942.1 - 1.6e-31 109.5 21.7 6.7e-31 107.5 20.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Rad51 PF08423.11 CEP19943.1 - 1.2e-40 139.4 0.1 1.5e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 CEP19943.1 - 2.1e-05 24.0 0.4 3.6e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CEP19943.1 - 2.9e-05 23.7 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF1118 PF06549.12 CEP19943.1 - 0.05 13.9 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Utp12 PF04003.12 CEP19944.1 - 6.5e-15 55.4 1.8 9.6e-15 54.8 1.8 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family CEP19 PF14933.6 CEP19944.1 - 0.32 11.3 13.4 1.1 9.5 13.4 2.0 1 1 0 1 1 1 0 CEP19-like protein Mg_trans_NIPA PF05653.14 CEP19945.1 - 6.9e-32 110.7 7.2 8.2e-32 110.5 7.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA YibE_F PF07907.11 CEP19945.1 - 0.019 14.5 2.3 0.026 14.0 2.3 1.2 1 0 0 1 1 1 0 YibE/F-like protein Glyco_transf_11 PF01531.16 CEP19945.1 - 0.051 12.8 0.1 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 MotA_ExbB PF01618.16 CEP19945.1 - 0.095 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF983 PF06170.12 CEP19945.1 - 0.53 10.7 3.1 0.39 11.1 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Hyr1 PF15789.5 CEP19946.1 - 0.62 9.7 6.2 0.19 11.3 2.2 2.4 2 1 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 RT_RNaseH_2 PF17919.1 CEP19947.1 - 1.8e-30 104.9 0.0 4.6e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP19947.1 - 7.8e-23 80.8 0.1 2.2e-22 79.3 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP19947.1 - 6e-16 58.7 0.0 2.2e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP19947.1 - 2.8e-15 56.4 0.1 6e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CEP19947.1 - 6.9e-10 38.9 0.3 6.9e-10 38.9 0.3 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CEP19947.1 - 4.6e-09 36.1 3.2 7.1e-08 32.2 2.7 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CEP19947.1 - 3.2e-06 27.3 0.0 1.4e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 H2C2 zinc finger Herpes_UL37_2 PF07413.11 CEP19947.1 - 0.0061 15.8 0.4 0.36 10.0 0.4 2.4 1 1 0 1 1 1 1 Betaherpesvirus immediate-early glycoprotein UL37 TraG_N PF07916.11 CEP19947.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region HSDR_N_2 PF13588.6 CEP19947.1 - 0.077 13.0 1.7 0.29 11.1 1.7 2.0 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Asp_protease_2 PF13650.6 CEP19947.1 - 0.098 13.3 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease PIF1 PF05970.14 CEP19950.1 - 5.9e-16 58.6 0.0 1.1e-14 54.4 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 CEP19950.1 - 1.9e-10 40.4 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CEP19950.1 - 1.5e-05 23.2 0.0 2.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CEP19950.1 - 3.1e-05 23.8 0.1 0.0001 22.1 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CEP19950.1 - 0.021 14.5 0.0 0.069 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Imm40 PF15569.6 CEP19952.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 40 NABP PF07990.12 CEP19953.1 - 0.22 11.0 5.7 0.28 10.7 5.7 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP PhoU PF01895.19 CEP19953.1 - 0.51 10.8 3.0 11 6.6 0.0 3.3 3 1 0 3 3 3 0 PhoU domain CCP_MauG PF03150.14 CEP19954.1 - 0.052 14.2 0.0 0.056 14.1 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase HlyD_D23 PF16576.5 CEP19955.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2151 PF10221.9 CEP19956.1 - 1.6e-08 33.6 1.0 1.4e-07 30.5 1.0 1.9 1 1 0 1 1 1 1 Cell cycle and development regulator FGE-sulfatase PF03781.16 CEP19957.1 - 1.3e-37 129.8 3.4 2.1e-37 129.1 3.4 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Kinesin PF00225.23 CEP19958.1 - 6.9e-113 376.9 1.1 6.9e-113 376.9 1.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 CEP19958.1 - 5.9e-48 163.4 2.3 5.9e-48 163.4 2.3 4.3 5 0 0 5 5 5 1 Kinesin-associated DUF3694 PF12473.8 CEP19958.1 - 2.3e-39 135.5 0.0 9.3e-39 133.5 0.0 2.2 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CEP19958.1 - 5e-29 101.2 0.1 2e-28 99.2 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CEP19958.1 - 2.1e-15 57.1 0.3 7.2e-15 55.4 0.3 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 CEP19958.1 - 1.4e-05 25.4 0.2 5.2e-05 23.6 0.2 2.0 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 CEP19958.1 - 0.27 11.6 2.4 0.7 10.3 0.2 2.9 3 0 0 3 3 3 0 FHA domain SUIM_assoc PF16619.5 CEP19958.1 - 0.71 10.0 28.9 5.8 7.1 19.2 4.3 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PH_9 PF15410.6 CEP19958.1 - 1.4 9.3 7.0 0.077 13.4 0.3 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Sec34 PF04136.15 CEP19958.1 - 4.4 7.2 11.2 4 7.3 0.9 2.9 2 0 0 2 2 2 0 Sec34-like family Sel1 PF08238.12 CEP19960.1 - 1.5e-34 117.6 19.3 2.1e-06 28.2 0.3 7.6 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 CEP19960.1 - 0.66 10.3 8.5 0.97 9.7 0.5 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA12 PF10443.9 CEP19961.1 - 2.2e-110 369.5 3.1 1.6e-69 234.7 0.7 2.1 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 CEP19961.1 - 9.6e-09 35.5 0.2 0.0018 18.2 0.0 2.9 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea RRM_1 PF00076.22 CEP19961.1 - 9.4e-06 25.4 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 CEP19961.1 - 0.00056 20.3 0.1 0.0018 18.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CEP19961.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2487 PF10673.9 CEP19961.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) DUF815 PF05673.13 CEP19961.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CEP19961.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mito_carr PF00153.27 CEP19962.1 - 1.2e-65 217.4 2.1 6.6e-22 77.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chitin_synth_2 PF03142.15 CEP19963.1 - 7.1e-95 318.6 12.4 1.4e-72 245.1 0.0 2.4 3 0 0 3 3 3 2 Chitin synthase Glycos_transf_2 PF00535.26 CEP19963.1 - 3.8e-05 23.5 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CEP19963.1 - 0.002 18.1 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CEP19963.1 - 0.0089 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 CCDC66 PF15236.6 CEP19963.1 - 1.8 8.4 5.2 3.9 7.3 5.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Cyclin PF08613.11 CEP19964.1 - 1e-08 35.7 3.1 4.5e-08 33.6 3.1 2.1 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CEP19964.1 - 0.023 14.5 0.7 0.023 14.5 0.7 2.7 2 1 0 2 2 2 0 Cyclin, N-terminal domain zf-RanBP PF00641.18 CEP19965.1 - 1.4e-09 37.1 2.1 2e-09 36.6 2.1 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CEP19965.1 - 1.1e-08 34.8 0.0 2.7e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) INTS5_N PF14837.6 CEP19966.1 - 0.018 14.6 0.3 0.52 9.9 0.0 2.8 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus CRM1_C PF08767.11 CEP19967.1 - 6.3e-05 22.3 3.9 0.0003 20.1 0.4 3.2 3 0 0 3 3 3 1 CRM1 C terminal Reprolysin_5 PF13688.6 CEP19968.1 - 1.1e-40 139.9 1.3 1.1e-40 139.9 1.3 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CEP19968.1 - 3.4e-39 134.8 1.6 5.5e-39 134.1 0.2 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CEP19968.1 - 1.4e-36 126.1 0.1 4e-36 124.6 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CEP19968.1 - 7.2e-13 49.2 0.0 3.5e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CEP19968.1 - 4.6e-06 27.3 12.2 4.6e-06 27.3 12.2 4.4 3 2 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.19 CEP19968.1 - 2.5e-05 24.5 1.0 3.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 CEP19968.1 - 0.00034 21.1 10.0 0.00034 21.1 10.0 3.5 2 1 1 3 3 3 1 ADAM cysteine-rich domain SAC3_GANP PF03399.16 CEP19968.1 - 0.04 13.3 0.8 0.067 12.6 0.8 1.2 1 0 0 1 1 1 0 SAC3/GANP family Muted PF14942.6 CEP19968.1 - 0.26 11.6 7.0 0.54 10.6 7.0 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein UDPGT PF00201.18 CEP19969.1 - 1.9e-28 99.5 0.1 4.5e-28 98.3 0.1 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CEP19969.1 - 4.5e-08 33.3 0.0 7.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TnpW PF14202.6 CEP19969.1 - 0.026 14.3 0.3 0.054 13.3 0.3 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpW zf-HC5HC2H_2 PF13832.6 CEP19970.1 - 1.5e-31 108.8 9.4 1.5e-31 108.8 9.4 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CEP19970.1 - 3.2e-25 88.2 7.5 3.2e-25 88.2 7.5 2.8 3 0 0 3 3 2 1 PHD-like zinc-binding domain Bromodomain PF00439.25 CEP19970.1 - 1.1e-20 73.4 0.7 5.3e-20 71.3 0.7 2.3 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.9 CEP19970.1 - 3.3e-20 73.1 10.3 3.3e-20 73.1 10.3 4.6 2 2 1 3 3 2 1 Enhancer of polycomb-like PHD_2 PF13831.6 CEP19970.1 - 1.5e-14 53.2 2.7 1.5e-14 53.2 2.7 2.9 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 CEP19970.1 - 4.7e-13 49.3 1.5 1.3e-12 47.9 0.2 2.5 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 CEP19970.1 - 1.8e-09 37.4 9.4 1.8e-09 37.4 9.4 2.9 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 CEP19970.1 - 0.011 15.3 2.3 0.011 15.3 2.3 2.4 2 0 0 2 2 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 CEP19970.1 - 0.016 15.1 1.6 0.016 15.1 1.6 2.5 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 CEP19970.1 - 0.072 13.0 1.1 0.45 10.5 1.1 2.5 1 0 0 1 1 1 0 AT hook motif Arm-DNA-bind_5 PF17293.2 CEP19970.1 - 1.6 9.3 10.4 17 6.0 0.6 4.2 4 0 0 4 4 4 0 Arm DNA-binding domain C1_2 PF03107.16 CEP19970.1 - 2.6 8.4 17.7 7.6 6.9 5.1 2.8 2 0 0 2 2 2 0 C1 domain DDE_3 PF13358.6 CEP19973.1 - 0.00045 20.0 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Polysacc_deac_2 PF04748.13 CEP19975.1 - 0.039 13.1 0.5 0.057 12.6 0.5 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Phage_connect_1 PF05135.13 CEP19975.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Transformer PF06495.11 CEP19977.1 - 0.013 15.6 5.3 0.023 14.8 5.3 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein PAP1 PF08601.10 CEP19977.1 - 0.33 10.6 3.9 0.38 10.4 3.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SH3_1 PF00018.28 CEP19979.1 - 1.4e-12 47.0 0.1 2.7e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CEP19979.1 - 3.6e-12 45.9 0.8 6.2e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CEP19979.1 - 8e-09 35.0 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CEP19979.1 - 0.031 14.3 0.3 0.086 12.9 0.3 1.7 1 0 0 1 1 1 0 WW domain Exonuc_VII_L PF02601.15 CEP19979.1 - 2.9 7.4 13.1 3.7 7.0 13.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 CEP19979.1 - 7.1 7.1 12.8 10 6.5 12.8 1.4 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 CEP19980.1 - 1.7e-50 171.8 0.0 2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CEP19980.1 - 8e-43 146.2 0.1 9.9e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CEP19980.1 - 1.3e-09 38.2 0.1 1.7e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CEP19980.1 - 0.0017 17.5 0.1 0.002 17.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PH PF00169.29 CEP19981.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 PH domain Sad1_UNC PF07738.13 CEP19982.1 - 2e-27 95.8 0.0 6e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1640 PF07798.11 CEP19982.1 - 0.019 15.0 1.1 0.042 13.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AgrB PF04647.15 CEP19982.1 - 0.99 8.7 5.1 1.7 7.9 5.1 1.3 1 0 0 1 1 1 0 Accessory gene regulator B PAP2_3 PF14378.6 CEP19982.1 - 1.3 8.7 7.4 22 4.7 8.2 2.0 1 1 1 2 2 2 0 PAP2 superfamily FliJ PF02050.16 CEP19982.1 - 1.7 8.9 8.2 11 6.3 5.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein CDP-OH_P_transf PF01066.21 CEP19983.1 - 9.6e-14 51.9 0.5 9.6e-14 51.9 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SAM_1 PF00536.30 CEP19985.1 - 0.0018 18.7 0.2 0.0039 17.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) COG5 PF10392.9 CEP19985.1 - 0.023 14.9 5.4 3.2 7.9 0.4 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 SAM_2 PF07647.17 CEP19985.1 - 0.023 14.8 0.1 0.093 12.9 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) NmrA PF05368.13 CEP19985.1 - 0.029 13.9 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family DUF4508 PF14969.6 CEP19985.1 - 0.13 12.6 0.0 0.57 10.5 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) CHCH PF06747.13 CEP19986.1 - 7.9e-08 32.2 3.4 1.5e-07 31.3 3.4 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CEP19986.1 - 0.0052 17.2 2.4 0.011 16.1 2.4 1.6 1 0 0 1 1 1 1 GCK domain ECSIT_C PF14784.6 CEP19986.1 - 0.019 15.3 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DHHW PF14286.6 CEP19986.1 - 0.3 10.3 6.9 0.19 11.0 1.6 2.0 2 0 0 2 2 2 0 DHHW protein Voldacs PF03517.13 CEP19986.1 - 3.5 7.8 9.2 3 8.0 6.4 2.3 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling PDZ_5 PF17817.1 CEP19987.1 - 0.001 19.3 0.2 0.0016 18.6 0.1 1.5 2 0 0 2 2 2 1 PDZ domain Med31 PF05669.12 CEP19987.1 - 0.027 14.5 0.2 0.051 13.6 0.2 1.5 1 1 1 2 2 2 0 SOH1 Bap31_Bap29_C PF18035.1 CEP19987.1 - 0.047 13.7 1.4 0.78 9.8 0.2 2.3 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2399 PF09664.10 CEP19987.1 - 0.066 13.1 0.9 0.074 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Cullin_binding PF03556.15 CEP19988.1 - 0.01 16.2 0.1 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 Cullin binding Pkinase PF00069.25 CEP19989.1 - 5.1e-57 193.2 0.0 1.9e-41 142.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CEP19989.1 - 2.2e-23 82.9 0.0 1.5e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP19989.1 - 2.5e-08 33.6 0.0 9.9e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CEP19989.1 - 1.6e-06 27.6 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CEP19989.1 - 5.5e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CEP19989.1 - 0.0031 16.3 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CEP19989.1 - 0.0069 16.0 0.1 0.0098 15.5 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CEP19989.1 - 0.021 13.8 0.1 0.042 12.8 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_L30 PF00327.20 CEP19990.1 - 4.2e-09 36.1 1.7 5.5e-09 35.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CEP19990.1 - 7.1e-07 29.4 12.2 7.1e-07 29.4 12.2 1.8 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Imm3 PF14425.6 CEP19990.1 - 0.11 12.5 2.0 1.7 8.7 0.0 2.7 3 0 0 3 3 3 0 Immunity protein Imm3 Coiled-coil_56 PF09813.9 CEP19990.1 - 0.12 12.4 5.7 0.27 11.3 5.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Phage_integrase PF00589.22 CEP19991.1 - 4.2e-05 23.4 0.3 0.00011 22.0 0.3 1.6 1 0 0 1 1 1 1 Phage integrase family Arf PF00025.21 CEP19992.1 - 5e-78 260.5 0.0 5.4e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CEP19992.1 - 6e-14 52.3 0.0 8.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CEP19992.1 - 1.3e-13 50.9 0.7 2e-09 37.1 0.2 2.4 2 1 1 3 3 3 2 G-protein alpha subunit SRPRB PF09439.10 CEP19992.1 - 4.7e-13 49.0 0.0 5.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CEP19992.1 - 9.6e-13 48.0 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CEP19992.1 - 1.2e-10 41.2 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CEP19992.1 - 3.5e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CEP19992.1 - 0.0054 16.1 0.8 0.018 14.4 0.8 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Peptidase_C48 PF02902.19 CEP19993.1 - 2.6e-22 79.7 0.2 5.1e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TPR_19 PF14559.6 CEP19993.1 - 2.2e-09 37.7 0.7 0.024 15.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CEP19993.1 - 1e-06 28.4 8.2 0.48 10.8 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CEP19993.1 - 6.7e-06 25.7 5.4 0.018 14.8 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CEP19993.1 - 2.7e-05 24.6 9.2 9.9 7.3 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CEP19993.1 - 4.2e-05 23.3 16.1 0.62 10.3 0.3 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CEP19993.1 - 5.1e-05 23.8 4.4 0.01 16.5 0.5 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CEP19993.1 - 0.0028 17.9 1.3 0.27 11.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CEP19993.1 - 0.0037 17.8 10.5 5.4 7.9 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CEP19993.1 - 0.02 15.2 0.3 0.02 15.2 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CEP19993.1 - 0.029 14.1 1.9 7.9 6.3 0.0 3.9 3 0 0 3 3 3 0 TPR repeat TPR_21 PF09976.9 CEP19993.1 - 0.065 12.9 5.0 0.082 12.6 0.3 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 CEP19993.1 - 0.084 12.9 3.9 29 5.0 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CEP19993.1 - 0.29 11.4 7.2 0.45 10.8 0.1 3.9 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NKAP PF15692.5 CEP19993.1 - 1.5 9.6 0.0 1.5 9.6 0.0 4.1 4 0 0 4 4 3 0 NF-kappa-B-activating protein RT_RNaseH_2 PF17919.1 CEP19995.1 - 2.8e-28 97.9 0.1 5.9e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP19995.1 - 3.8e-21 75.3 0.0 1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CEP19995.1 - 5.6e-07 30.1 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CEP19995.1 - 6e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CEP19995.1 - 1.2e-05 25.1 0.3 2.9e-05 23.9 0.3 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 CEP19995.1 - 0.024 14.3 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVP PF00077.20 CEP19995.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Pepsin-I3 PF06394.13 CEP19995.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain COMMD1_N PF17221.3 CEP19997.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 COMMD1 N-terminal domain Peptidase_M54 PF07998.11 CEP19999.1 - 0.064 13.2 0.1 0.077 13.0 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M54 RT_RNaseH PF17917.1 CEP20001.1 - 7.5e-16 58.3 0.0 8.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CEP20001.1 - 2.5e-07 30.6 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIF1 PF05970.14 CEP20003.1 - 1.5e-103 346.8 0.0 2e-103 346.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CEP20003.1 - 6.8e-11 42.2 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CEP20003.1 - 8.7e-05 22.9 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CEP20003.1 - 0.0004 18.5 0.0 0.0012 16.9 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 CEP20003.1 - 0.03 14.7 0.0 1 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain UvrD_C_2 PF13538.6 CEP20003.1 - 0.037 13.8 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CEP20003.1 - 0.043 13.5 0.0 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CEP20003.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 CEP20003.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CEP20003.1 - 0.16 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain zf-ribbon_3 PF13248.6 CEP20004.1 - 2e-06 27.0 16.3 0.51 9.8 0.3 5.4 5 0 0 5 5 5 4 zinc-ribbon domain zf-RING_7 PF02591.15 CEP20004.1 - 7e-06 26.1 14.2 0.88 9.8 0.1 5.0 5 0 0 5 5 5 3 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 CEP20004.1 - 7e-06 26.2 17.8 0.2 12.0 0.1 5.3 5 0 0 5 5 5 3 zinc-ribbon Lar_restr_allev PF14354.6 CEP20004.1 - 8.2e-05 22.9 21.7 0.013 15.9 0.7 4.4 2 2 1 3 3 3 2 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CEP20004.1 - 0.00048 20.1 27.4 0.41 10.7 1.5 5.1 4 1 1 5 5 5 3 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.19 CEP20004.1 - 0.0062 16.9 8.4 0.0062 16.9 8.4 4.1 2 1 3 5 5 5 2 DnaJ central domain zf-C4_Topoisom PF01396.19 CEP20004.1 - 0.015 15.0 14.6 8.3 6.3 0.4 5.1 5 0 0 5 5 5 0 Topoisomerase DNA binding C4 zinc finger PhnA_Zn_Ribbon PF08274.12 CEP20004.1 - 0.037 14.0 16.7 1.1 9.3 0.2 5.1 5 0 0 5 5 5 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.6 CEP20004.1 - 0.043 13.5 19.3 4.1 7.3 0.2 5.1 5 0 0 5 5 5 0 zinc-ribbon domain UPF0547 PF10571.9 CEP20004.1 - 0.093 12.8 20.2 1.9 8.6 0.2 5.0 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 CEP20004.1 - 0.1 12.8 24.8 0.69 10.1 0.4 5.2 4 2 2 6 6 6 0 Zinc ribbon domain zf-Di19 PF05605.12 CEP20004.1 - 0.15 12.3 17.6 4.6 7.6 0.3 4.7 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 CEP20004.1 - 0.23 11.4 33.5 0.6 10.1 1.9 5.6 3 2 2 5 5 5 0 Prokaryotic RING finger family 1 zf-TFIIB PF13453.6 CEP20004.1 - 0.31 10.4 13.4 0.6 9.5 2.6 4.1 4 1 0 4 4 4 0 Transcription factor zinc-finger DUF1356 PF07092.12 CEP20004.1 - 0.38 10.0 10.0 5.1 6.3 0.8 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF1356) zf-LITAF-like PF10601.9 CEP20004.1 - 0.45 10.8 20.5 0.9 9.9 0.3 5.0 5 0 0 5 5 5 0 LITAF-like zinc ribbon domain HypA PF01155.19 CEP20004.1 - 0.48 10.5 15.2 1 9.4 1.5 3.7 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 CEP20004.1 - 0.99 9.2 11.0 73 3.3 0.1 5.2 5 0 0 5 5 5 0 HypF finger zf_CopZ PF18423.1 CEP20004.1 - 1.2 9.2 13.3 35 4.5 0.3 4.4 4 0 0 4 4 4 0 Zinc binding domain zinc-ribbons_6 PF07191.12 CEP20004.1 - 2.6 8.1 21.4 0.54 10.3 2.3 4.2 2 2 1 3 3 3 0 zinc-ribbons Terminase_GpA PF05876.12 CEP20004.1 - 3.8 6.0 7.7 1.9 7.0 1.9 2.1 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.6 CEP20004.1 - 3.8 7.5 15.0 3.3 7.7 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain Ogr_Delta PF04606.12 CEP20004.1 - 4.7 7.3 32.9 3 7.9 0.7 5.8 5 1 1 6 6 6 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.6 CEP20004.1 - 4.8 7.2 19.5 10 6.1 0.2 4.7 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_Rg PF17915.1 CEP20004.1 - 5.6 6.5 11.5 10 5.6 0.3 3.8 4 0 0 4 4 4 0 Reverse gyrase zinc finger MqsA_antitoxin PF15731.5 CEP20004.1 - 5.8 7.0 8.1 0.28 11.3 0.2 2.7 3 1 1 4 4 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FYDLN_acid PF09538.10 CEP20004.1 - 7.2 7.3 11.4 2.4 8.9 0.1 4.1 2 2 3 5 5 5 0 Protein of unknown function (FYDLN_acid) Cys_rich_KTR PF14205.6 CEP20004.1 - 8.5 6.3 11.7 50 3.8 0.1 4.6 5 0 0 5 5 5 0 Cysteine-rich KTR NDC10_II PF16787.5 CEP20005.1 - 9e-10 38.1 0.4 1.4e-09 37.5 0.4 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 SWC7 PF17330.2 CEP20005.1 - 0.11 12.5 0.6 0.22 11.6 0.2 1.7 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 rve PF00665.26 CEP20006.1 - 4e-11 43.1 0.0 6.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Fib_alpha PF08702.10 CEP20007.1 - 0.036 14.3 0.5 0.062 13.5 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HlyD_2 PF12700.7 CEP20007.1 - 0.091 11.5 1.5 0.12 11.1 1.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein zf-C2HC PF01530.18 CEP20007.1 - 0.11 12.7 0.1 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2HC type MFS_1 PF07690.16 CEP20008.1 - 3.8e-53 180.7 29.9 3.8e-53 180.7 29.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CEP20008.1 - 3.3e-14 52.6 6.1 3.3e-14 52.6 6.1 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CEP20008.1 - 4.5e-06 25.4 3.5 4.5e-06 25.4 3.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LRR19-TM PF15176.6 CEP20008.1 - 0.44 10.6 2.1 5.2 7.1 0.2 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF2373 PF10180.9 CEP20009.1 - 8.2e-18 64.0 1.5 1.7e-17 63.0 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Polysacc_deac_1 PF01522.21 CEP20009.1 - 4.4e-12 46.0 0.1 1.5e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1943 PF09172.11 CEP20009.1 - 0.0042 16.4 6.8 0.01 15.1 6.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Spt5_N PF11942.8 CEP20010.1 - 1 10.4 11.3 15 6.6 6.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Prok-RING_1 PF14446.6 CEP20011.1 - 0.017 15.0 0.5 0.017 15.0 0.5 4.2 4 1 1 5 5 5 0 Prokaryotic RING finger family 1 zf-CCHC PF00098.23 CEP20011.1 - 0.024 14.7 4.4 0.22 11.7 0.4 4.4 5 0 0 5 5 4 0 Zinc knuckle zinc_ribbon_2 PF13240.6 CEP20011.1 - 0.084 12.6 11.0 1.7 8.5 0.3 4.6 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 CEP20011.1 - 0.087 12.9 16.7 1 9.4 1.7 3.4 2 2 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CEP20011.1 - 0.088 12.8 16.5 0.34 10.9 2.6 3.2 2 1 1 3 3 3 0 zinc-ribbons Nudix_N_2 PF14803.6 CEP20011.1 - 0.1 12.5 9.6 0.59 10.1 0.1 3.8 4 0 0 4 4 4 0 Nudix N-terminal DUF4611 PF15387.6 CEP20011.1 - 0.12 12.6 1.3 4.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Myc_target_1 PF15179.6 CEP20011.1 - 0.19 11.6 4.8 0.65 9.9 0.1 2.1 1 1 1 2 2 2 0 Myc target protein 1 zf-RING_7 PF02591.15 CEP20011.1 - 0.33 11.2 8.8 0.42 10.8 0.1 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-H2C2_2 PF13465.6 CEP20011.1 - 0.5 10.9 11.3 8.7 7.0 0.1 4.5 4 1 1 5 5 4 0 Zinc-finger double domain Ribosomal_L32p PF01783.23 CEP20011.1 - 0.62 10.4 14.9 3.3 8.0 5.9 3.8 3 1 1 4 4 4 0 Ribosomal L32p protein family YhfH PF14149.6 CEP20011.1 - 0.76 9.8 8.1 18 5.4 0.0 3.4 3 0 0 3 3 3 0 YhfH-like protein DZR PF12773.7 CEP20011.1 - 0.8 9.8 17.6 1.4 9.0 3.2 3.7 2 2 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 CEP20011.1 - 0.96 9.5 4.8 9.9 6.2 0.1 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 CEP20011.1 - 1.3 8.5 14.1 1.1 8.8 0.3 4.5 5 0 0 5 5 5 0 zinc-ribbon domain DUF3268 PF11672.8 CEP20011.1 - 1.7 9.0 6.3 2 8.8 0.1 2.7 3 0 0 3 3 3 0 zinc-finger-containing domain zf_UBZ PF18439.1 CEP20011.1 - 3.4 7.3 13.9 4.4 7.0 0.1 4.5 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 CEP20011.1 - 3.5 7.6 17.2 29 4.7 0.7 4.1 2 2 1 3 3 3 0 PHD-finger OrfB_Zn_ribbon PF07282.11 CEP20011.1 - 4.1 7.4 15.6 5.3 7.0 1.7 3.6 3 1 0 3 3 3 0 Putative transposase DNA-binding domain DUF35_N PF12172.8 CEP20011.1 - 8.2 6.4 9.9 33 4.5 0.8 3.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Peptidase_C1_2 PF03051.15 CEP20012.1 - 1.2e-167 558.1 0.2 1.5e-167 557.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CEP20012.1 - 0.0048 17.0 3.0 0.55 10.3 0.3 2.7 3 0 0 3 3 3 2 Papain family cysteine protease Pcc1 PF09341.10 CEP20013.1 - 1.4e-21 76.4 0.2 1.6e-21 76.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Rol_Rep_N PF18106.1 CEP20013.1 - 0.051 13.9 0.1 0.093 13.1 0.0 1.4 1 1 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain Ras PF00071.22 CEP20014.1 - 2.4e-55 186.5 0.2 2.8e-55 186.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CEP20014.1 - 2.1e-21 76.4 0.0 3.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CEP20014.1 - 6.4e-08 32.2 0.2 8.8e-08 31.8 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CEP20014.1 - 1.5e-05 24.7 0.2 3.7e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CEP20014.1 - 7.7e-05 22.7 0.1 0.00012 22.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CEP20014.1 - 0.0015 18.5 0.6 1.8 8.4 0.6 2.4 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CEP20014.1 - 0.016 14.4 0.2 2 7.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 CEP20014.1 - 0.075 13.1 0.1 0.16 12.0 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain LRR_4 PF12799.7 CEP20015.1 - 8.8e-05 22.8 16.5 0.037 14.5 0.9 5.2 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) NRho PF16733.5 CEP20015.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Rhomboid N-terminal domain LRR_8 PF13855.6 CEP20015.1 - 0.042 13.6 12.6 0.33 10.8 0.5 4.2 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 CEP20015.1 - 7.1 7.0 13.4 13 6.1 1.6 4.8 5 0 0 5 5 5 0 Leucine Rich repeat ORC_WH_C PF18137.1 CEP20016.1 - 0.071 13.2 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Androgen_recep PF02166.16 CEP20016.1 - 5.1 5.8 9.3 7.5 5.3 9.3 1.2 1 0 0 1 1 1 0 Androgen receptor Rad60-SLD PF11976.8 CEP20017.1 - 0.11 12.4 0.2 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like CoiA PF06054.11 CEP20018.1 - 0.19 10.8 0.4 0.32 10.1 0.4 1.3 1 0 0 1 1 1 0 Competence protein CoiA-like family RVT_1 PF00078.27 CEP20019.1 - 2.2e-09 37.1 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP20019.1 - 0.00043 19.9 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-bind_4 PF13837.6 CEP20022.1 - 0.0016 18.8 0.2 0.0025 18.1 0.2 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Plant_tran PF04827.14 CEP20023.1 - 1.3e-35 122.9 0.1 2.3e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein ComR_TPR PF18710.1 CEP20023.1 - 0.0021 17.6 0.2 0.0028 17.2 0.2 1.3 1 0 0 1 1 1 1 ComR tetratricopeptide HTH_Tnp_1 PF01527.20 CEP20025.1 - 0.038 14.3 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 Transposase Dynamitin PF04912.14 CEP20028.1 - 0.034 13.5 8.7 0.046 13.0 8.7 1.1 1 0 0 1 1 1 0 Dynamitin TrbM PF07424.11 CEP20028.1 - 0.046 13.7 1.4 1.3 9.0 0.5 2.2 2 0 0 2 2 2 0 TrbM DDE_3 PF13358.6 CEP20029.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 CEP20029.1 - 0.0056 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain F-box-like PF12937.7 CEP20030.1 - 0.00025 20.9 0.3 0.00076 19.3 0.1 1.9 2 0 0 2 2 2 1 F-box-like LOB PF03195.14 CEP20030.1 - 0.094 13.3 0.0 0.58 10.8 0.0 2.4 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain Mpp10 PF04006.12 CEP20032.1 - 2.4e-162 541.6 90.9 2.7e-162 541.4 90.9 1.0 1 0 0 1 1 1 1 Mpp10 protein PLDc PF00614.22 CEP20033.1 - 1.5e-15 56.6 0.5 1.8e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CEP20033.1 - 1e-13 51.3 0.1 9.4e-08 32.0 0.0 3.8 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 CEP20033.1 - 4.3e-08 33.1 1.9 4.3e-08 33.1 1.9 3.5 4 0 0 4 4 4 1 PX domain Dynamin_N PF00350.23 CEP20034.1 - 8.4e-20 71.5 0.8 8.4e-20 71.5 0.8 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CEP20034.1 - 2.5e-12 46.9 0.2 2.5e-12 46.9 0.2 2.9 4 1 0 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CEP20034.1 - 8.7e-06 25.4 9.1 8.3e-05 22.2 8.8 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 CEP20034.1 - 5.4e-05 23.2 0.8 0.13 12.3 0.0 2.9 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CEP20034.1 - 0.00058 20.1 0.2 0.028 14.6 0.0 2.8 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CEP20034.1 - 0.0013 18.4 7.9 0.0064 16.1 0.4 3.7 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CEP20034.1 - 0.0019 18.1 7.0 0.4 10.6 0.7 3.7 3 1 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CEP20034.1 - 0.0034 17.8 0.1 0.021 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 CEP20034.1 - 0.011 15.2 0.9 2.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CEP20034.1 - 0.012 15.4 1.1 6.2 6.6 0.0 3.2 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CEP20034.1 - 0.02 14.4 0.2 0.17 11.4 0.2 2.5 1 1 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_D PF01813.17 CEP20034.1 - 0.02 14.7 2.6 0.075 12.8 1.1 2.4 2 0 0 2 2 2 0 ATP synthase subunit D IIGP PF05049.13 CEP20034.1 - 0.034 13.2 8.3 0.063 12.3 0.1 3.0 3 1 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 CEP20034.1 - 0.035 13.8 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIID-31kDa PF02291.15 CEP20034.1 - 0.036 14.2 0.1 1.9 8.6 0.0 3.4 3 1 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit DUF4715 PF15835.5 CEP20034.1 - 0.1 12.7 2.2 4.9 7.2 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4715) INCENP_ARK-bind PF03941.15 CEP20035.1 - 1.5e-10 40.8 0.2 4.2e-10 39.4 0.2 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region She9_MDM33 PF05546.11 CEP20036.1 - 7e-70 234.9 13.1 7e-70 234.9 13.1 1.9 2 0 0 2 2 2 1 She9 / Mdm33 family CH_2 PF06294.11 CEP20036.1 - 0.028 14.6 0.9 0.051 13.7 0.2 1.8 2 0 0 2 2 2 0 CH-like domain in sperm protein DUF1028 PF06267.12 CEP20036.1 - 0.63 9.8 3.6 2.8 7.7 0.4 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF1028) Snapin_Pallidin PF14712.6 CEP20036.1 - 4.4 7.8 14.0 1.3 9.4 6.5 3.2 2 1 0 2 2 2 0 Snapin/Pallidin PhoU PF01895.19 CEP20036.1 - 5.1 7.6 6.7 1.3 9.5 0.1 3.0 3 0 0 3 3 3 0 PhoU domain UBN_AB PF14075.6 CEP20037.1 - 1.4e-33 116.5 1.9 1.4e-33 116.5 1.9 3.5 3 1 1 4 4 4 1 Ubinuclein conserved middle domain HUN PF08729.10 CEP20037.1 - 5.7e-09 35.8 7.8 5.7e-09 35.8 7.8 2.0 1 1 1 2 2 2 1 HPC2 and ubinuclein domain zf-Tim10_DDP PF02953.15 CEP20038.1 - 1.6e-19 69.3 1.9 2.2e-19 68.8 1.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.12 CEP20038.1 - 0.027 14.9 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 Vps54-like protein DUF1980 PF09323.10 CEP20039.1 - 0.02 14.8 1.8 1.5 8.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) PapB PF03333.13 CEP20040.1 - 0.038 14.0 0.2 0.099 12.7 0.1 1.7 1 1 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein RGS PF00615.19 CEP20041.1 - 0.00084 19.6 0.0 0.0017 18.6 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF3671 PF12420.8 CEP20041.1 - 0.051 13.7 10.6 0.16 12.1 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF1980 PF09323.10 CEP20041.1 - 0.51 10.2 4.7 0.7 9.8 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) SAYSvFN PF10260.9 CEP20041.1 - 0.97 9.4 4.9 6.6 6.7 0.5 2.9 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Tmpp129 PF10272.9 CEP20041.1 - 1.1 8.5 5.8 0.13 11.5 1.3 1.7 2 0 0 2 2 2 0 Putative transmembrane protein precursor 7tm_1 PF00001.21 CEP20041.1 - 1.3 8.3 11.7 0.21 10.9 3.7 2.6 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) HHV-5_US34A PF17087.5 CEP20041.1 - 3.2 8.0 4.3 7.7 6.7 0.9 2.6 1 1 1 2 2 2 0 Herpesvirus US34A protein family DUF2721 PF11026.8 CEP20041.1 - 9.1 6.2 7.1 2.8 7.8 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF4407 PF14362.6 CEP20042.1 - 0.02 14.3 0.3 0.02 14.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Endonuc_Holl PF10107.9 CEP20042.1 - 0.028 14.3 2.0 0.034 14.0 2.0 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3106 PF11304.8 CEP20042.1 - 0.03 14.8 6.7 0.13 12.8 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) OmpH PF03938.14 CEP20042.1 - 0.041 14.2 9.0 0.067 13.5 9.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MYO10_CC PF16735.5 CEP20042.1 - 3.6 7.7 11.1 1.4 9.1 5.5 2.4 2 1 0 2 2 2 0 Unconventional myosin-X coiled coil domain Rgp1 PF08737.10 CEP20045.1 - 1.1 8.3 7.6 1.5 7.9 7.6 1.1 1 0 0 1 1 1 0 Rgp1 MID_MedPIWI PF18296.1 CEP20045.1 - 1.2 8.9 9.4 1.7 8.3 9.4 1.3 1 0 0 1 1 1 0 MID domain of medPIWI GREB1 PF15782.5 CEP20045.1 - 4 4.4 13.3 4.7 4.2 13.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Phage_integrase PF00589.22 CEP20046.1 - 0.00025 20.9 0.1 0.00038 20.3 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 CEP20047.1 - 0.031 14.8 2.0 0.047 14.2 2.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RT_RNaseH PF17917.1 CEP20048.1 - 0.0018 18.6 2.8 0.096 13.0 0.3 3.1 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DNA_pol_viral_C PF00336.18 CEP20048.1 - 0.061 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Sif PF06767.11 CEP20049.1 - 0.084 11.8 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Sif protein Aldo_ket_red PF00248.21 CEP20050.1 - 7.5e-24 84.4 0.1 5e-16 58.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family zf-C2H2_6 PF13912.6 CEP20051.1 - 0.00022 21.1 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CEP20051.1 - 0.035 14.9 0.1 0.054 14.4 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger p450 PF00067.22 CEP20052.1 - 8e-80 268.8 0.3 1e-79 268.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Alpha-E PF04168.12 CEP20052.1 - 0.059 13.1 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. HSP20 PF00011.21 CEP20053.1 - 1.1e-21 76.9 0.6 1e-13 51.3 0.2 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CEP20053.1 - 4.3e-09 35.8 0.0 1.1e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Ribosomal_L36 PF00444.18 CEP20054.1 - 5.1e-18 65.0 11.8 6.7e-18 64.6 11.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 WD40 PF00400.32 CEP20055.1 - 1.2e-21 76.6 17.4 7.5e-05 23.4 1.2 10.9 11 0 0 11 11 11 6 WD domain, G-beta repeat tRNA-synt_1 PF00133.22 CEP20056.1 - 1.2e-212 707.4 0.0 1.2e-211 704.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CEP20056.1 - 3e-36 124.7 0.1 6.2e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CEP20056.1 - 1.4e-12 47.1 2.4 3e-06 26.2 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CEP20056.1 - 9e-10 38.4 0.3 1.9e-07 30.7 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 NAD_binding_10 PF13460.6 CEP20056.1 - 9.2e-07 28.9 0.0 5.5e-05 23.1 0.0 2.8 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CEP20056.1 - 0.00095 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family tRNA-synt_1e PF01406.19 CEP20056.1 - 0.042 13.2 0.0 0.6 9.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain adh_short PF00106.25 CEP20056.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 CEP20056.1 - 0.13 11.3 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Spaetzle PF16077.5 CEP20057.1 - 0.0027 18.2 0.5 0.007 16.9 0.1 1.8 1 1 1 2 2 2 1 Spaetzle MAP70 PF07058.11 CEP20057.1 - 5.7 5.5 6.9 2.5 6.7 3.2 1.8 1 1 1 2 2 2 0 Microtubule-associated protein 70 Luciferase_N PF05295.11 CEP20058.1 - 0.077 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain RasGEF PF00617.19 CEP20059.1 - 1.8e-42 145.6 0.1 3.9e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain Usp PF00582.26 CEP20061.1 - 3.9e-06 27.4 0.2 1.2e-05 25.9 0.0 1.9 2 1 0 2 2 2 1 Universal stress protein family Receptor_2B4 PF11465.8 CEP20061.1 - 0.032 14.4 0.3 1.3 9.2 0.3 2.6 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 DpaA_N PF16924.5 CEP20061.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain zf-C2H2 PF00096.26 CEP20062.1 - 1.6e-05 25.0 19.3 0.0018 18.6 0.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP20062.1 - 0.00014 22.4 17.9 0.18 12.7 0.9 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEP20062.1 - 0.00049 20.3 12.7 0.039 14.1 1.3 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger DUF4867 PF16161.5 CEP20062.1 - 0.085 12.3 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4867) zf-H2C2_2 PF13465.6 CEP20062.1 - 0.21 12.1 15.0 0.19 12.2 0.9 3.6 3 1 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 CEP20062.1 - 6.6 5.1 9.9 0.22 10.0 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Gti1_Pac2 PF09729.9 CEP20063.1 - 2.7e-58 197.0 1.1 2.7e-58 197.0 1.1 3.6 2 2 0 2 2 2 1 Gti1/Pac2 family Tubulin_2 PF13809.6 CEP20063.1 - 0.039 13.1 1.1 0.071 12.3 1.1 1.4 1 0 0 1 1 1 0 Tubulin like Pkinase PF00069.25 CEP20064.1 - 6.3e-49 166.7 0.0 8.7e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP20064.1 - 6.8e-28 97.6 0.0 8.8e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CEP20064.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CEP20064.1 - 0.0022 18.0 0.1 0.0059 16.6 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CEP20064.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain His_Phos_1 PF00300.22 CEP20066.1 - 8.8e-12 45.1 0.0 8e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CEP20066.1 - 0.0031 16.9 0.1 0.0053 16.2 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) rve PF00665.26 CEP20067.1 - 5.8e-08 32.9 0.0 8.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain NDC10_II PF16787.5 CEP20070.1 - 4e-35 121.4 0.0 1.2e-32 113.2 0.0 2.1 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Caskin-tail PF16632.5 CEP20070.1 - 0.22 12.0 2.7 0.83 10.1 0.4 2.3 2 0 0 2 2 2 0 C-terminal region of Caskin DDE_3 PF13358.6 CEP20071.1 - 8.2e-23 80.8 0.0 1.1e-20 73.8 0.0 2.7 1 1 0 1 1 1 1 DDE superfamily endonuclease F-box-like PF12937.7 CEP20071.1 - 2.3e-05 24.2 0.1 5.9e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CEP20071.1 - 4.3e-05 23.3 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUSP PF06337.12 CEP20071.1 - 5.7e-05 23.7 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 DUSP domain C1_1 PF00130.22 CEP20071.1 - 8.2 6.4 12.8 1.4 8.8 4.5 3.4 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MULE PF10551.9 CEP20073.1 - 5e-09 36.4 1.3 2.7e-07 30.9 0.2 3.2 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 CEP20073.1 - 3.4e-05 22.9 0.7 5.3e-05 22.3 0.7 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 CEP20073.1 - 0.009 15.8 0.6 0.024 14.4 0.4 1.8 2 0 0 2 2 2 1 Transposase AAT PF03417.16 CEP20073.1 - 0.027 14.1 0.5 0.069 12.8 0.5 1.7 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase REV PF00424.18 CEP20073.1 - 0.13 12.3 1.1 0.71 9.9 0.4 2.5 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) YrzK PF17449.2 CEP20074.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized YrzK-like ODC_AZ PF02100.17 CEP20077.1 - 1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme RVT_1 PF00078.27 CEP20079.1 - 3.8e-35 121.4 0.0 8.4e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CEP20079.1 - 4.3e-05 24.1 0.1 4.3e-05 24.1 0.1 3.1 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase YL1 PF05764.13 CEP20079.1 - 0.015 15.5 7.4 0.036 14.2 7.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein DDE_3 PF13358.6 CEP20079.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3716 PF12511.8 CEP20079.1 - 0.86 9.7 3.2 2.4 8.3 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PBP1_TM PF14812.6 CEP20079.1 - 3.3 8.1 10.0 14 6.1 4.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mpv17_PMP22 PF04117.12 CEP20081.1 - 8.7e-25 86.7 1.2 2.1e-24 85.5 0.3 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family zf-C2H2 PF00096.26 CEP20082.1 - 2e-07 31.1 7.9 0.00015 22.0 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CEP20082.1 - 4.5e-06 26.9 1.8 4.5e-06 26.9 1.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CEP20082.1 - 0.0071 17.1 6.1 0.95 10.5 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CEP20082.1 - 0.031 14.5 1.1 0.14 12.5 1.1 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CEP20082.1 - 0.07 13.2 0.1 0.07 13.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CEP20082.1 - 0.4 11.3 4.7 1.3 9.7 0.1 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain ANTH PF07651.16 CEP20084.1 - 6.2e-35 120.5 5.8 2e-33 115.6 2.3 2.3 1 1 1 2 2 2 2 ANTH domain Ribosomal_L5_C PF00673.21 CEP20086.1 - 2.4e-22 78.9 0.0 6.7e-22 77.5 0.0 1.7 1 1 1 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CEP20086.1 - 3.3e-19 69.0 0.0 9.8e-19 67.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HLH PF00010.26 CEP20087.1 - 4.8e-12 45.6 0.2 4.8e-12 45.6 0.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain His_Phos_2 PF00328.22 CEP20088.1 - 1e-23 84.3 0.0 4.1e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAM176 PF14851.6 CEP20090.1 - 0.0064 16.2 1.2 0.0065 16.1 0.1 1.6 2 0 0 2 2 2 1 FAM176 family stn_TNFRSF12A PF12191.8 CEP20090.1 - 0.0067 16.7 0.2 0.15 12.3 0.0 2.5 2 1 1 3 3 3 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PepSY_TM PF03929.16 CEP20090.1 - 0.069 12.8 0.1 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 PepSY-associated TM region Phage_holin_2_4 PF16082.5 CEP20090.1 - 0.072 12.8 0.7 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Trp_oprn_chp PF09534.10 CEP20090.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PBP1_TM PF14812.6 CEP20090.1 - 0.23 11.9 6.3 0.45 10.9 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Alpha_GJ PF03229.13 CEP20090.1 - 0.34 11.5 9.1 8.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Alphavirus glycoprotein J SPX PF03105.19 CEP20090.1 - 0.47 10.3 6.3 0.6 10.0 6.1 1.3 1 1 0 1 1 1 0 SPX domain DSPc PF00782.20 CEP20091.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CEP20091.1 - 0.00023 20.8 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NDC10_II PF16787.5 CEP20093.1 - 0.00037 19.6 0.4 0.00079 18.6 0.1 1.6 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF5521 PF17659.1 CEP20093.1 - 0.038 11.8 0.1 0.057 11.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Glyco_hydro_47 PF01532.20 CEP20095.1 - 1.7e-165 551.3 0.0 2e-165 551.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 CEP20095.1 - 0.0043 16.6 1.3 1.8 8.0 0.0 2.7 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 CEP20095.1 - 0.015 14.5 0.5 2.3 7.4 0.0 3.2 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Mito_carr PF00153.27 CEP20096.1 - 7.4e-55 182.9 1.7 6.6e-20 70.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_deac_1 PF01522.21 CEP20096.1 - 0.0048 16.8 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Serine_protease PF18405.1 CEP20096.1 - 0.12 11.5 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease PIF1 PF05970.14 CEP20097.1 - 0.0049 16.1 0.0 0.0065 15.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DDE_1 PF03184.19 CEP20099.1 - 3.2e-19 69.3 0.1 4.9e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 CEP20099.1 - 0.0037 17.0 0.0 0.0095 15.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Aha1_N PF09229.11 CEP20100.1 - 3.5e-34 118.0 0.1 5.9e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF727 PF05303.12 CEP20101.1 - 6.5e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Arrestin_N PF00339.29 CEP20102.1 - 2.4e-06 27.7 0.6 6.6e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CEP20102.1 - 5.2e-05 23.7 0.0 0.0051 17.3 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RHD3 PF05879.12 CEP20102.1 - 0.021 13.0 2.6 1.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) LDB19 PF13002.7 CEP20102.1 - 0.072 12.8 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like bHLH-MYC_N PF14215.6 CEP20102.1 - 0.15 12.4 0.4 0.71 10.1 0.1 2.1 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal SSP160 PF06933.11 CEP20102.1 - 6.5 4.8 13.4 12 4.0 13.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UreD PF01774.17 CEP20103.1 - 5.2e-59 199.7 0.0 6.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein CoA_binding PF02629.19 CEP20104.1 - 1.4e-26 93.0 0.8 1.4e-26 93.0 0.8 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CEP20104.1 - 2.9e-22 79.2 0.2 4.9e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CEP20104.1 - 5.3e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CEP20104.1 - 0.002 18.6 0.0 0.0092 16.5 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Herpes_capsid PF06112.11 CEP20105.1 - 0.23 11.5 9.1 0.47 10.5 9.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein OrfB_Zn_ribbon PF07282.11 CEP20106.1 - 0.00081 19.3 0.1 0.00081 19.3 0.1 2.4 3 0 0 3 3 3 1 Putative transposase DNA-binding domain DUF739 PF05339.11 CEP20106.1 - 0.012 15.8 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF739) zf-CCHC PF00098.23 CEP20106.1 - 0.045 13.8 1.7 0.045 13.8 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RVT PF13966.6 CEP20107.1 - 1.5e-07 32.0 0.5 1.5e-07 32.0 0.5 2.4 3 1 0 3 3 3 1 zinc-binding in reverse transcriptase Wza_C PF18412.1 CEP20107.1 - 0.023 14.4 0.0 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain Endonuclease_7 PF02945.15 CEP20107.1 - 0.12 12.4 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII RVT_1 PF00078.27 CEP20108.1 - 3.9e-25 88.7 0.1 4.8e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L13e PF01294.18 CEP20112.1 - 2.2e-78 262.2 4.1 3.1e-78 261.7 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e bZIP_1 PF00170.21 CEP20113.1 - 1.7e-10 40.8 12.8 3.4e-10 39.9 12.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CEP20113.1 - 1.2e-05 25.3 13.2 2.8e-05 24.1 13.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper CCDC154 PF15450.6 CEP20113.1 - 0.0047 15.5 3.5 0.0062 15.1 3.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 HALZ PF02183.18 CEP20113.1 - 0.011 16.0 2.7 0.021 15.0 2.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 CEP20113.1 - 0.016 15.7 6.9 0.04 14.4 6.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor zf-CCCH_2 PF14608.6 CEP20115.1 - 0.00063 20.1 43.7 0.014 15.8 5.0 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Mito_carr PF00153.27 CEP20116.1 - 5.9e-66 218.5 3.0 2.3e-24 85.1 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Glucosamine_iso PF01182.20 CEP20116.1 - 1.4e-18 67.6 0.0 2.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ACAS_N PF16177.5 CEP20116.1 - 0.45 10.5 2.4 1.4 8.9 2.4 1.8 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus RINGv PF12906.7 CEP20117.1 - 2.2e-07 30.9 9.9 3.6e-07 30.2 9.9 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 CEP20117.1 - 0.001 19.2 5.8 0.002 18.2 5.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 CEP20117.1 - 0.0016 18.7 7.7 0.0028 17.9 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zinc_ribbon_4 PF13717.6 CEP20117.1 - 0.077 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 CEP20117.1 - 0.15 11.9 5.1 0.31 10.9 5.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CEP20117.1 - 0.17 11.6 4.5 0.36 10.5 4.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CEP20117.1 - 2.4 8.1 7.0 4.1 7.4 7.0 1.4 1 0 0 1 1 1 0 PHD-finger Fip1 PF05182.13 CEP20118.1 - 3.3e-25 87.3 0.7 6.3e-25 86.4 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif Spore_coat_CotO PF14153.6 CEP20118.1 - 1.7 8.6 16.3 3 7.7 16.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Macoilin PF09726.9 CEP20118.1 - 2.9 6.3 7.1 5 5.6 7.1 1.3 1 0 0 1 1 1 0 Macoilin family Sporozoite_P67 PF05642.11 CEP20118.1 - 7.1 4.6 13.3 14 3.6 13.3 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CRM1_C PF08767.11 CEP20119.1 - 9.1e-63 212.3 10.8 9.1e-63 212.3 10.8 3.7 3 2 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CEP20119.1 - 5.7e-31 107.6 6.0 5.7e-31 107.6 6.0 4.7 2 2 2 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CEP20119.1 - 3.9e-24 84.1 0.7 3.3e-23 81.1 0.0 3.0 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CEP20119.1 - 4e-14 52.5 0.4 1.8e-13 50.3 0.4 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 CEP20119.1 - 2.3e-11 43.4 2.2 9.9e-11 41.4 0.9 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CEP20119.1 - 1.5 9.5 6.4 40 4.9 0.0 4.6 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region SAP PF02037.27 CEP20121.1 - 1.6e-11 43.7 0.1 3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 CEP20121.1 - 0.042 13.2 0.2 0.071 12.4 0.2 1.4 1 0 0 1 1 1 0 LETM1-like protein DUF4287 PF14117.6 CEP20121.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Spc7 PF08317.11 CEP20123.1 - 0.00049 19.1 14.9 0.00049 19.1 14.9 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF4201 PF13870.6 CEP20123.1 - 0.01 15.6 4.5 0.01 15.6 4.5 4.0 2 1 1 4 4 4 0 Domain of unknown function (DUF4201) RPW8 PF05659.11 CEP20123.1 - 0.032 13.9 2.7 0.081 12.6 1.4 2.3 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Synaptonemal_3 PF15191.6 CEP20123.1 - 0.093 12.5 5.0 0.093 12.5 1.3 2.5 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 HAP1_N PF04849.13 CEP20123.1 - 0.095 11.9 37.9 0.69 9.1 13.4 3.7 1 1 3 4 4 4 0 HAP1 N-terminal conserved region Snapin_Pallidin PF14712.6 CEP20123.1 - 0.19 12.2 22.7 0.11 12.9 3.8 4.1 5 1 0 5 5 5 0 Snapin/Pallidin DUF4349 PF14257.6 CEP20123.1 - 0.43 10.0 13.3 1.9 7.9 7.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF1664 PF07889.12 CEP20123.1 - 0.47 10.5 18.0 0.048 13.7 6.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 CEP20123.1 - 0.53 10.3 30.0 0.91 9.5 4.9 3.1 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.12 CEP20123.1 - 1 7.8 6.6 1.8 7.0 6.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ABC_tran_CTD PF16326.5 CEP20123.1 - 3 8.2 24.6 0.2 11.9 5.7 3.7 4 0 0 4 4 3 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 CEP20123.1 - 8 7.0 10.3 17 5.9 1.1 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) NDC10_II PF16787.5 CEP20124.1 - 4e-43 147.7 0.5 7.6e-41 140.2 0.0 2.6 2 1 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP20124.1 - 1.3e-37 128.0 0.6 3e-23 81.9 0.3 3.2 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DNA_pol_A_exo1 PF01612.20 CEP20124.1 - 7.9e-16 58.3 0.1 7.9e-16 58.3 0.1 2.3 2 0 0 2 2 2 1 3'-5' exonuclease Sif PF06767.11 CEP20124.1 - 0.16 11.0 5.2 0.095 11.7 0.5 2.5 3 0 0 3 3 3 0 Sif protein Histone_HNS PF00816.21 CEP20124.1 - 1.9 9.3 4.2 16 6.4 0.3 3.4 3 0 0 3 3 3 0 H-NS histone family TMEM141 PF15110.6 CEP20126.1 - 0.017 15.7 0.2 0.028 15.0 0.2 1.3 1 0 0 1 1 1 0 TMEM141 protein family SUIM_assoc PF16619.5 CEP20127.1 - 0.012 15.7 4.9 0.012 15.7 4.9 3.9 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Dehydrin PF00257.19 CEP20127.1 - 4.7 7.7 6.5 3.6 8.1 2.8 2.3 2 0 0 2 2 2 0 Dehydrin Sec66 PF09802.9 CEP20128.1 - 3.9e-45 153.6 2.3 3.9e-45 153.6 2.3 1.6 1 1 1 2 2 2 1 Preprotein translocase subunit Sec66 Sporozoite_P67 PF05642.11 CEP20128.1 - 0.72 7.9 5.6 0.85 7.6 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GAGA_bind PF06217.12 CEP20128.1 - 1.5 9.0 11.4 1.7 8.9 11.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CEP20128.1 - 4.9 6.9 16.1 5.8 6.7 16.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CEP20128.1 - 5.2 7.1 6.3 6.3 6.8 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CcmF_C PF16327.5 CEP20129.1 - 0.0016 17.8 2.3 0.0016 17.8 2.3 1.8 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Apq12 PF12716.7 CEP20130.1 - 0.00018 21.3 12.4 0.00031 20.6 12.4 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis MgtE PF01769.16 CEP20130.1 - 0.021 15.2 5.6 0.025 14.9 5.6 1.2 1 0 0 1 1 1 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 CEP20130.1 - 0.15 12.1 0.8 0.24 11.4 0.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 CEP20130.1 - 5.9 7.1 5.1 4.9 7.4 3.6 1.6 1 1 1 2 2 2 0 HemY protein N-terminus p450 PF00067.22 CEP20131.1 - 1.6e-73 248.1 0.0 2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDC10_II PF16787.5 CEP20132.1 - 7.7e-42 143.5 0.3 1.5e-38 132.7 0.3 2.4 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CEP20132.1 - 5.5e-19 68.3 3.4 2e-18 66.5 3.4 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_5 PF08360.11 CEP20132.1 - 0.0096 16.1 2.4 0.018 15.2 0.9 2.3 2 0 0 2 2 2 1 QacR-like protein, C-terminal region Phage_integrase PF00589.22 CEP20132.1 - 0.03 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Phage integrase family Flavi_capsid PF01003.19 CEP20132.1 - 0.27 11.0 1.3 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 Flavivirus capsid protein C Pkinase PF00069.25 CEP20133.1 - 6.3e-73 245.4 0.0 9.1e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP20133.1 - 2e-35 122.3 0.0 2.9e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP20133.1 - 1.3e-05 24.6 0.0 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CEP20133.1 - 0.025 14.2 0.4 1.7 8.2 0.0 2.6 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pribosyltran_N PF13793.6 CEP20134.1 - 5.9e-46 155.2 1.5 2.9e-45 152.9 0.2 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CEP20134.1 - 9e-43 146.4 8.5 1.9e-36 125.8 2.8 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CEP20134.1 - 3.7e-15 55.8 1.7 1.2e-14 54.1 0.9 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CEP20134.1 - 0.013 15.0 2.0 0.042 13.3 0.3 2.2 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase UPF0181 PF03701.14 CEP20134.1 - 0.022 14.4 1.2 0.43 10.2 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) RGS PF00615.19 CEP20136.1 - 0.00013 22.2 0.0 0.00032 21.0 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain PDEase_I PF00233.19 CEP20137.1 - 9e-69 231.8 0.6 9e-69 231.8 0.6 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase ChaC PF04752.12 CEP20137.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 ChaC-like protein HD PF01966.22 CEP20137.1 - 0.036 14.3 0.1 0.078 13.2 0.1 1.6 1 0 0 1 1 1 0 HD domain Tristanin_u2 PF16638.5 CEP20137.1 - 0.69 10.7 5.0 2.7 8.8 5.0 2.0 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers LysM PF01476.20 CEP20138.1 - 3.1e-11 43.1 0.1 0.00017 21.6 0.0 2.7 2 0 0 2 2 2 2 LysM domain Cadherin_3 PF16184.5 CEP20138.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like CD99L2 PF12301.8 CEP20139.1 - 0.031 14.6 0.3 0.035 14.4 0.3 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 Ycf34 PF10718.9 CEP20140.1 - 0.039 14.7 0.1 0.091 13.5 0.1 1.6 1 1 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 DUF2779 PF11074.8 CEP20140.1 - 0.06 13.8 3.5 0.21 12.0 3.4 1.9 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) Nup54 PF13874.6 CEP20140.1 - 0.24 11.5 2.5 2.3 8.3 0.3 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 XhlA PF10779.9 CEP20140.1 - 0.25 11.6 3.4 0.43 10.8 0.7 2.4 2 0 0 2 2 2 0 Haemolysin XhlA TolA_bind_tri PF16331.5 CEP20140.1 - 0.58 10.3 3.9 0.31 11.1 1.6 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation LMBR1 PF04791.16 CEP20140.1 - 1.2 8.0 5.2 1.5 7.7 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DDE_Tnp_1_7 PF13843.6 CEP20141.1 - 1.9e-22 80.1 0.0 2.3e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 tRNA-synt_1g PF09334.11 CEP20143.1 - 3.5e-151 503.4 0.1 4.5e-151 503.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CEP20143.1 - 1.5e-08 33.4 0.0 1.8e-05 23.2 0.0 2.7 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_C_3 PF14497.6 CEP20143.1 - 0.015 15.5 0.1 0.044 14.0 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zinc-ribbons_6 PF07191.12 CEP20143.1 - 0.021 14.8 3.0 0.053 13.5 3.0 1.6 1 0 0 1 1 1 0 zinc-ribbons MetRS-N PF09635.10 CEP20143.1 - 0.029 14.9 0.3 0.068 13.7 0.3 1.6 1 0 0 1 1 1 0 MetRS-N binding domain HypA PF01155.19 CEP20143.1 - 0.24 11.4 2.3 0.68 10.0 1.9 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 CEP20144.1 - 3.4e-24 84.1 21.3 1.9e-07 31.2 0.5 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CEP20144.1 - 1.1e-21 76.0 30.9 9.2e-06 25.8 2.0 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CEP20144.1 - 3e-10 40.0 27.7 0.0026 18.4 1.4 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CEP20144.1 - 0.0025 18.1 4.9 2.7 8.4 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CEP20144.1 - 0.023 15.3 9.7 6.6 7.4 0.1 3.9 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-met PF12874.7 CEP20144.1 - 0.029 14.8 7.9 25 5.4 0.1 4.8 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CEP20144.1 - 0.034 13.9 13.2 0.98 9.2 0.6 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-TRAF PF02176.18 CEP20144.1 - 0.54 11.0 12.8 0.2 12.4 2.1 3.2 2 1 1 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.12 CEP20144.1 - 0.84 9.7 9.6 0.11 12.5 0.7 3.6 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 CEP20144.1 - 1.1 9.3 16.0 2.9 8.0 0.8 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CEP20144.1 - 3.3 7.8 7.9 11 6.2 0.5 3.0 1 1 2 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 CEP20144.1 - 5.1 7.1 11.1 13 5.8 0.6 4.2 4 1 0 4 4 4 0 LYAR-type C2HC zinc finger ABC_membrane PF00664.23 CEP20145.1 - 9.4e-29 100.9 10.2 1.3e-28 100.5 10.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CEP20145.1 - 1.1e-21 77.7 1.3 2.5e-21 76.6 0.0 2.2 3 0 0 3 3 3 1 ABC transporter Spp-24 PF07448.11 CEP20145.1 - 0.087 13.0 0.7 0.22 11.7 0.7 1.6 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain PIN_2 PF10130.9 CEP20145.1 - 0.23 11.7 2.8 0.22 11.8 0.5 2.2 2 1 1 3 3 3 0 PIN domain Pkinase PF00069.25 CEP20146.1 - 2.9e-61 207.1 0.0 6.1e-60 202.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP20146.1 - 1.4e-38 132.7 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CEP20146.1 - 2.3e-06 26.6 0.1 1.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CEP20146.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CEP20146.1 - 0.031 13.3 0.1 0.062 12.3 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CEP20146.1 - 0.045 12.7 0.0 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 CEP20146.1 - 0.064 13.2 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L37e PF01907.19 CEP20147.1 - 4.7e-27 93.9 12.7 9.1e-27 93.0 12.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CEP20147.1 - 0.0063 16.5 1.3 0.01 15.9 1.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 CEP20147.1 - 0.01 15.9 0.7 0.014 15.4 0.7 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SelR PF01641.18 CEP20147.1 - 0.027 14.5 1.6 0.041 14.0 1.6 1.5 1 1 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 CEP20147.1 - 0.2 11.6 6.6 0.13 12.3 4.4 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 CEP20147.1 - 0.55 9.7 4.8 3.3 7.3 3.5 2.5 2 1 1 3 3 3 0 zinc-ribbon domain DUF2845 PF11006.8 CEP20147.1 - 0.59 10.3 4.0 3.1 8.0 2.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2845) zinc_ribbon_2 PF13240.6 CEP20147.1 - 1 9.2 5.1 21 5.0 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 CEP20147.1 - 2.6 8.0 6.5 4.6 7.2 6.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.16 CEP20147.1 - 2.7 7.9 6.5 1.1e+02 2.8 6.5 2.8 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Formyl_trans_N PF00551.19 CEP20149.1 - 1.4e-28 99.9 0.0 2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CEP20149.1 - 7.7e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Tau95_N PF17682.1 CEP20151.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 Tau95 Triple barrel domain NLRC4_HD2 PF17776.1 CEP20153.1 - 1 9.9 4.2 4.3 7.9 0.2 2.7 1 1 2 3 3 3 0 NLRC4 helical domain HD2 DDE_Tnp_1_7 PF13843.6 CEP20154.1 - 8.3e-07 28.6 0.0 8.3e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_3 PF13358.6 CEP20155.1 - 1.9e-06 27.7 0.0 9e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease RT_RNaseH_2 PF17919.1 CEP20157.1 - 1.7e-32 111.4 0.1 3.7e-32 110.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CEP20157.1 - 8.6e-29 99.9 0.4 1.8e-28 98.9 0.4 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CEP20157.1 - 1e-16 61.2 0.0 3.2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CEP20157.1 - 3.1e-15 56.3 0.8 7.2e-15 55.1 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 CEP20157.1 - 7.1e-10 38.6 1.2 1.9e-09 37.3 1.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 CEP20157.1 - 2.3e-08 34.0 0.0 6.8e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CEP20157.1 - 0.00026 21.5 0.0 0.00067 20.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CEP20157.1 - 0.00042 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CEP20157.1 - 0.0071 16.5 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 CEP20157.1 - 0.02 14.7 0.1 0.06 13.1 0.1 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A17 PF05380.13 CEP20157.1 - 0.079 13.0 0.3 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Pao retrotransposon peptidase 4HBT PF03061.22 CEP20159.1 - 5.6e-10 39.4 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CEP20159.1 - 1.3e-06 27.9 0.0 5.1e-05 22.7 0.5 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 CEP20159.1 - 1.2e-05 25.8 0.0 1.5e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF5390 PF17365.2 CEP20159.1 - 0.0029 17.9 0.3 0.0039 17.5 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5390) VIT PF08487.10 CEP20159.1 - 0.13 12.5 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain TRAM_LAG1_CLN8 PF03798.16 CEP20160.1 - 4.9e-42 143.9 19.0 4.9e-42 143.9 19.0 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CEP20160.1 - 1.2e-14 53.7 2.0 1.2e-14 53.7 2.0 2.2 3 0 0 3 3 3 1 TRAM1-like protein DUF4834 PF16118.5 CEP20160.1 - 7.7 7.5 7.6 11 7.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Pox_A_type_inc PF04508.12 CEP20161.1 - 0.0014 18.4 1.9 0.0014 18.4 1.9 7.0 7 0 0 7 7 7 1 Viral A-type inclusion protein repeat DUF2258 PF10015.9 CEP20161.1 - 2.6 8.2 7.0 14 5.9 0.1 4.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2258) DASH_Dam1 PF08653.10 CEP20161.1 - 4.4 7.2 21.8 1.4 8.8 0.2 7.1 6 1 0 6 6 6 0 DASH complex subunit Dam1 Methyltransf_11 PF08241.12 CEP20162.1 - 1.4e-05 25.6 0.0 3.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CEP20162.1 - 0.0001 22.9 0.0 0.00028 21.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CEP20162.1 - 0.00015 21.6 0.1 0.00023 21.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.13 CEP20162.1 - 0.00017 21.2 0.2 0.0017 17.9 0.2 2.2 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 CEP20162.1 - 0.0025 17.8 0.2 0.0052 16.7 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CEP20162.1 - 0.0066 15.5 0.1 0.0099 15.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.18 CEP20162.1 - 0.0085 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 CEP20162.1 - 0.013 16.3 0.3 0.08 13.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 CEP20162.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 AATF-Che1 PF13339.6 CEP20162.1 - 0.25 12.0 3.6 0.8 10.4 0.0 2.6 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Aa_trans PF01490.18 CEP20163.1 - 4.5e-49 167.3 32.5 5.5e-49 167.0 32.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4731 PF15875.5 CEP20163.1 - 0.8 9.9 0.0 0.8 9.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4731) KaiA PF07688.12 CEP20164.1 - 0.085 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiA C-terminal domain DUF2700 PF10912.8 CEP20164.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) WD40 PF00400.32 CEP20165.1 - 1.7e-07 31.8 13.7 0.18 12.8 0.7 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Dynein_IC2 PF11540.8 CEP20165.1 - 6e-05 22.9 0.3 0.00014 21.7 0.3 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 CEP20165.1 - 0.015 15.5 0.0 0.085 13.2 0.0 2.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4407 PF14362.6 CEP20165.1 - 1.5 8.1 14.1 2.3 7.5 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CEP20165.1 - 2.6 8.1 18.1 2.8 8.0 11.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus NIBRIN_BRCT_II PF16508.5 CEP20166.1 - 1.3e-13 51.3 0.0 5.2e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT_2 PF16589.5 CEP20166.1 - 0.026 14.9 0.1 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Cupin_8 PF13621.6 CEP20167.1 - 7.9e-22 78.2 0.2 1.8e-21 77.0 0.2 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CEP20167.1 - 1.8e-16 60.6 0.3 6e-16 58.9 0.0 2.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase DUF4667 PF15700.5 CEP20167.1 - 1.9 8.5 10.8 0.033 14.3 3.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SR-25 PF10500.9 CEP20167.1 - 7.8 6.0 25.6 0.17 11.4 13.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CEP20168.1 - 2.6e-68 230.3 0.0 3.9e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CEP20168.1 - 1.6e-35 122.6 0.0 2.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CEP20168.1 - 5.1e-09 35.9 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CEP20168.1 - 0.0014 18.1 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CEP20168.1 - 0.0025 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CEP20168.1 - 0.044 12.7 0.2 0.077 11.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CEP20168.1 - 0.052 12.5 0.1 0.087 11.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CEP20168.1 - 0.08 12.8 0.6 0.15 12.0 0.6 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WDCP PF15390.6 CEP20168.1 - 0.25 9.7 0.3 0.43 8.9 0.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Myosin_head PF00063.21 CEP20169.1 - 2.9e-248 825.6 5.5 2.9e-248 825.6 5.5 2.0 3 0 0 3 3 3 1 Myosin head (motor domain) IQ PF00612.27 CEP20169.1 - 0.052 13.4 0.2 0.052 13.4 0.2 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif RNA_helicase PF00910.22 CEP20169.1 - 0.084 13.3 0.5 11 6.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 CEP20169.1 - 0.44 10.8 0.0 0.44 10.8 0.0 4.2 2 1 3 5 5 5 0 AAA domain AAA_16 PF13191.6 CEP20169.1 - 0.58 10.5 0.0 0.58 10.5 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain Pex14_N PF04695.13 CEP20170.1 - 0.0013 19.4 10.6 0.0013 19.4 10.6 3.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 CEP20170.1 - 0.03 13.3 22.1 0.12 11.3 10.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 CEP20170.1 - 0.063 12.0 1.0 0.12 11.1 1.0 1.3 1 1 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CEP20170.1 - 0.18 11.5 4.6 3.2 7.5 0.7 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Fes1 PF08609.10 CEP20170.1 - 1.2 10.1 10.2 5.3 8.0 3.4 2.7 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 DUF1178 PF06676.11 CEP20170.1 - 1.2 9.5 8.3 6.2 7.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) 7TM_transglut PF14402.6 CEP20170.1 - 10 5.5 6.9 22 4.4 6.9 1.5 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Dynamin_M PF01031.20 CEP20171.1 - 9.1e-104 346.7 0.1 9.1e-104 346.7 0.1 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CEP20171.1 - 8.6e-56 188.6 0.4 2.2e-55 187.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CEP20171.1 - 2.2e-30 104.6 6.4 2.2e-30 104.6 6.4 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CEP20171.1 - 0.00029 20.9 2.4 0.00039 20.5 0.4 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase NPH3 PF03000.14 CEP20171.1 - 0.052 13.2 0.3 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 NPH3 family FeoB_N PF02421.18 CEP20171.1 - 0.082 12.4 0.2 13 5.3 0.1 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 CEP20171.1 - 0.19 12.1 0.4 0.87 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 CEP20171.1 - 0.53 9.9 7.9 5.5 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Sec7_N PF12783.7 CEP20171.1 - 0.54 10.2 4.8 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Strep_SA_rep PF06696.11 CEP20171.1 - 0.59 10.2 2.8 1.5 8.9 2.8 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF755 PF05501.11 CEP20171.1 - 7 6.9 8.4 1.1 9.6 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Strep_SA_rep PF06696.11 CEP20172.1 - 0.079 13.0 1.2 0.48 10.5 1.2 2.4 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Tli4_N PF18443.1 CEP20172.1 - 0.088 13.2 0.6 0.25 11.7 0.6 1.8 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain NFRKB_winged PF14465.6 CEP20172.1 - 0.091 13.0 1.6 2.9 8.1 0.2 2.6 2 0 0 2 2 2 0 NFRKB Winged Helix-like Noelin-1 PF12308.8 CEP20172.1 - 1.6 8.8 5.7 5.7 7.0 0.3 3.3 3 0 0 3 3 3 0 Neurogenesis glycoprotein APG6_N PF17675.1 CEP20172.1 - 1.7 9.1 28.2 1.4 9.4 7.5 4.2 4 0 0 4 4 4 0 Apg6 coiled-coil region YabA PF06156.13 CEP20172.1 - 3.5 8.3 13.2 9.2 7.0 0.8 3.6 3 1 0 3 3 3 0 Initiation control protein YabA HALZ PF02183.18 CEP20172.1 - 4.2 7.7 12.6 0.078 13.2 2.1 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper zf-CCHC PF00098.23 CEP20173.1 - 0.00052 20.0 9.5 0.19 11.9 0.4 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CEP20173.1 - 1.4 9.0 5.8 6 6.9 5.8 2.1 1 1 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CEP20173.1 - 4.9 7.1 6.1 3 7.8 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CEP20173.1 - 6.4 6.6 6.6 2.8 7.7 1.0 2.5 1 1 1 2 2 2 0 Zinc knuckle bZIP_1 PF00170.21 CEP20174.1 - 0.00014 21.8 16.4 0.00082 19.4 16.4 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CEP20174.1 - 0.00022 21.7 8.1 0.00022 21.7 8.1 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor FSA_C PF10479.9 CEP20174.1 - 0.052 11.7 8.3 0.072 11.2 8.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus KASH_CCD PF14662.6 CEP20174.1 - 0.12 12.2 8.8 0.027 14.3 5.2 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3439 PF11921.8 CEP20174.1 - 0.13 12.2 10.2 0.27 11.2 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CEP20174.1 - 0.19 9.6 10.9 0.031 12.3 7.2 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein bZIP_2 PF07716.15 CEP20174.1 - 0.23 11.6 27.1 0.062 13.4 20.2 2.7 2 1 0 2 2 2 0 Basic region leucine zipper SSP160 PF06933.11 CEP20174.1 - 0.29 9.3 12.7 0.38 8.9 12.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 APG6_N PF17675.1 CEP20174.1 - 0.42 11.2 7.7 0.18 12.4 4.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Nif11 PF07862.11 CEP20174.1 - 0.43 10.9 2.5 3.3 8.1 0.1 2.7 2 1 0 2 2 2 0 Nif11 domain GAS PF13851.6 CEP20174.1 - 0.49 9.7 12.2 0.054 12.9 8.0 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MGC-24 PF05283.11 CEP20174.1 - 1.3 9.5 8.6 2.6 8.5 8.6 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin UPF0242 PF06785.11 CEP20174.1 - 1.4 9.0 8.1 0.38 10.8 4.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 CEP20174.1 - 8.9 5.6 9.2 5.7 6.2 5.9 1.9 2 0 0 2 2 2 0 FAM76 protein AAA_33 PF13671.6 CEP20175.1 - 1.1e-11 45.0 0.1 1.9e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CEP20175.1 - 0.0017 17.8 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RVT_1 PF00078.27 CEP20176.1 - 5.9e-36 124.0 1.0 1.2e-25 90.3 0.1 3.8 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) EPL1 PF10513.9 CEP20176.1 - 1.7 9.0 12.5 0.84 10.0 9.1 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like CPSF100_C PF13299.6 CEP20176.1 - 6.6 6.9 8.4 15 5.8 8.4 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Exo_endo_phos_2 PF14529.6 CEP20177.1 - 1.4e-16 60.4 6.7 5.2e-13 48.9 0.2 3.9 4 0 0 4 4 4 2 Endonuclease-reverse transcriptase MsyB PF13984.6 CEP20177.1 - 0.0053 17.1 2.2 3.4 8.0 0.0 3.0 3 0 0 3 3 3 2 MsyB protein HHH_2 PF12826.7 CEP20177.1 - 0.013 15.6 0.3 9.3 6.4 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif Swi5 PF07061.11 CEP20177.1 - 0.18 11.9 3.3 0.54 10.4 0.0 2.8 3 0 0 3 3 3 0 Swi5 DUF4907 PF16250.5 CEP20177.1 - 0.28 11.1 3.2 6.6 6.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4907) ApoC-I PF04691.12 CEP20177.1 - 0.43 10.5 4.5 13 5.8 0.3 2.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) TFIIA PF03153.13 CEP20178.1 - 1.5 8.7 24.7 2.2 8.2 24.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRCC4 PF06632.12 CEP20178.1 - 4.1 6.2 6.4 4.7 6.0 6.4 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Roughex PF06020.11 CEP20178.1 - 6.2 5.8 8.7 8.7 5.3 8.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein RVT_1 PF00078.27 CEP20179.1 - 4.5e-21 75.4 0.0 9.9e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5611 PF18446.1 CEP20181.1 - 0.015 16.2 0.1 0.018 15.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) DUF4417 PF14386.6 CEP20181.1 - 0.026 14.1 0.1 0.031 13.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4417) HlyD_2 PF12700.7 CEP20182.1 - 0.73 8.5 3.1 0.99 8.1 3.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF3808 PF10300.9 CEP20184.1 - 3.9e-86 289.7 11.8 2.5e-59 201.3 2.7 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF3808) Phage_Mu_F PF04233.14 CEP20184.1 - 0.082 13.7 3.5 4.5 8.0 2.9 2.7 2 0 0 2 2 2 0 Phage Mu protein F like protein TPR_8 PF13181.6 CEP20184.1 - 3.7 8.0 6.7 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CEP20185.1 - 8.9e-06 26.2 2.1 0.0024 18.5 0.1 3.5 3 1 0 3 3 3 1 Sel1 repeat FSA_C PF10479.9 CEP20185.1 - 2 6.5 9.0 2.8 5.9 9.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SF3A3 PF16837.5 CEP20186.1 - 0.086 13.4 1.3 0.27 11.8 1.3 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Eapp_C PF10238.9 CEP20186.1 - 0.95 9.5 4.9 1.6 8.8 4.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein MS_channel PF00924.18 CEP20188.1 - 7.4e-21 74.6 0.5 1.2e-20 74.0 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 CEP20188.1 - 7.3e-05 22.4 0.1 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CEP20188.1 - 0.00011 21.5 0.1 0.00011 21.5 0.1 2.1 2 0 0 2 2 2 1 EF hand DUF2207 PF09972.9 CEP20188.1 - 0.00077 18.3 0.1 0.32 9.7 0.0 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) EF-hand_5 PF13202.6 CEP20188.1 - 0.0017 17.7 0.2 0.0054 16.2 0.2 1.8 1 0 0 1 1 1 1 EF hand Ferlin_C PF16165.5 CEP20188.1 - 0.0023 17.9 0.0 0.0023 17.9 0.0 2.2 3 0 0 3 3 3 1 Ferlin C-terminus EF-hand_7 PF13499.6 CEP20188.1 - 0.0033 17.8 0.5 0.028 14.9 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair Claudin_2 PF13903.6 CEP20188.1 - 0.21 11.3 13.8 0.092 12.5 0.8 3.4 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Colicin_im PF03857.13 CEP20188.1 - 0.37 10.7 3.3 0.12 12.4 0.2 1.7 2 0 0 2 2 2 0 Colicin immunity protein ATP_synt_H PF05493.13 CEP20188.1 - 1 9.9 13.1 0.038 14.5 5.7 2.5 2 1 0 2 2 2 0 ATP synthase subunit H Homeodomain PF00046.29 CEP20189.1 - 3.7e-18 65.1 2.1 3.7e-18 65.1 2.1 2.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CEP20189.1 - 0.069 13.1 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 CEP20189.1 - 0.073 12.9 0.2 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF719 PF05334.13 CEP20189.1 - 0.75 10.0 4.2 2.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF719) DUF2417 PF10329.9 CEP20190.1 - 0.042 13.3 0.2 0.67 9.3 0.1 2.0 2 0 0 2 2 2 0 Region of unknown function (DUF2417) CH PF00307.31 CEP20191.1 - 6.9e-48 161.4 1.4 8.3e-23 80.7 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 CEP20191.1 - 2.6e-10 40.2 0.3 7.5e-10 38.8 0.3 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CEP20191.1 - 2.5e-09 36.8 0.1 6.2e-05 22.7 0.0 3.2 2 1 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CEP20191.1 - 0.00038 20.5 0.8 0.15 12.1 0.2 3.0 3 0 0 3 3 3 1 CH-like domain in sperm protein Spectrin PF00435.21 CEP20191.1 - 0.0022 18.4 5.6 0.0043 17.5 0.6 2.9 2 1 0 2 2 2 1 Spectrin repeat SatD PF16264.5 CEP20191.1 - 0.0038 16.9 1.8 0.012 15.3 0.2 2.3 2 0 0 2 2 2 1 SatD family (SatD) DASH_Duo1 PF08651.10 CEP20191.1 - 0.023 14.5 1.9 0.38 10.6 0.8 2.9 1 1 1 2 2 2 0 DASH complex subunit Duo1 Apolipoprotein PF01442.18 CEP20191.1 - 0.042 13.7 1.4 0.088 12.7 1.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CEP20191.1 - 0.053 13.6 1.5 8.2 6.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IMD PF08397.11 CEP20191.1 - 0.075 12.4 2.6 0.42 10.0 0.1 2.6 2 1 0 2 2 2 0 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.22 CEP20191.1 - 0.094 13.0 3.8 0.12 12.6 1.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SesA PF17107.5 CEP20191.1 - 0.11 12.7 2.9 38 4.5 0.0 3.5 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 CEP20191.1 - 0.37 10.8 5.7 0.087 12.9 1.7 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 CEP20191.1 - 0.87 10.2 3.6 1 9.9 0.8 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal OrfB_Zn_ribbon PF07282.11 CEP20192.1 - 5.6e-09 35.8 0.3 5.6e-09 35.8 0.3 3.6 3 0 0 3 3 3 2 Putative transposase DNA-binding domain zf-CCHC_3 PF13917.6 CEP20192.1 - 0.8 9.7 10.0 1.3 9.1 0.3 3.3 3 0 0 3 3 3 0 Zinc knuckle DZR PF12773.7 CEP20192.1 - 3.7 7.7 8.7 5.8 7.0 0.4 3.5 3 0 0 3 3 3 0 Double zinc ribbon zf-CCHC PF00098.23 CEP20192.1 - 4.8 7.4 11.5 5.3 7.3 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle OrfB_Zn_ribbon PF07282.11 CEP20193.1 - 1.2e-09 38.0 0.1 1.2e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Crystall PF00030.19 CEP20193.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Beta/Gamma crystallin Latexin PF06907.12 CEP20193.1 - 0.088 12.3 0.4 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 Latexin zf-DNL PF05180.12 CEP20193.1 - 0.58 10.1 2.9 0.56 10.2 0.8 2.0 2 0 0 2 2 2 0 DNL zinc finger Homeodomain PF00046.29 CEP20194.1 - 0.059 13.2 0.1 9.1 6.2 0.0 2.8 2 0 0 2 2 2 0 Homeodomain RVT_1 PF00078.27 CEP20197.1 - 3.4e-23 82.3 0.0 6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.21 CEP20198.1 - 2.2e-17 63.1 0.1 7.5e-11 42.1 0.0 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CEP20198.1 - 1.1e-06 28.1 0.0 6e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DSPc PF00782.20 CEP20199.1 - 6.3e-11 42.2 11.8 6.7e-11 42.1 0.0 4.3 4 1 1 5 5 5 1 Dual specificity phosphatase, catalytic domain Abhydrolase_6 PF12697.7 CEP20199.1 - 5.3e-09 37.0 0.0 1.2e-08 35.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CEP20199.1 - 1.4e-08 34.7 0.1 7.1e-08 32.4 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CEP20199.1 - 4.4e-05 23.4 0.0 4.4e-05 23.4 0.0 2.7 2 0 0 2 2 2 1 Serine hydrolase Y_phosphatase PF00102.27 CEP20199.1 - 0.0024 17.5 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CEP20199.1 - 0.05 13.7 0.1 0.05 13.7 0.1 4.8 2 1 2 4 4 4 0 Inositol hexakisphosphate Lipase_3 PF01764.25 CEP20199.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.6 3 0 0 3 3 3 0 Lipase (class 3) Glyco_hydro_9 PF00759.19 CEP20199.1 - 7.4 5.9 12.3 87 2.4 11.1 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 9 TBPIP PF07106.13 CEP20200.1 - 4.2e-19 68.2 2.5 5.3e-19 67.9 0.5 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 CEP20200.1 - 1.5e-10 41.0 0.1 1.5e-10 41.0 0.1 2.2 2 0 0 2 2 1 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 CEP20200.1 - 0.00018 21.9 0.2 0.0037 17.6 0.4 2.4 2 1 0 2 2 2 1 Penicillinase repressor YabA PF06156.13 CEP20200.1 - 0.0019 18.8 6.2 0.052 14.2 6.9 2.4 1 1 1 2 2 2 1 Initiation control protein YabA RraB PF06877.11 CEP20200.1 - 0.0037 18.0 0.2 0.0085 16.8 0.2 1.7 1 0 0 1 1 1 1 Regulator of ribonuclease activity B UPF0242 PF06785.11 CEP20200.1 - 0.0077 16.4 5.2 0.012 15.8 5.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 CEP20200.1 - 0.0096 15.9 5.7 0.018 15.0 5.7 1.6 1 0 0 1 1 1 1 Axonemal dynein light chain Occludin_ELL PF07303.13 CEP20200.1 - 0.013 16.3 3.4 0.013 16.3 3.4 2.5 3 0 0 3 3 3 0 Occludin homology domain DUF812 PF05667.11 CEP20200.1 - 0.013 14.4 8.1 0.016 14.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 CEP20200.1 - 0.015 15.7 14.5 1.8 9.1 14.5 2.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF2730 PF10805.8 CEP20200.1 - 0.016 15.3 7.1 0.44 10.7 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF4140 PF13600.6 CEP20200.1 - 0.037 14.5 1.3 0.037 14.5 1.3 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NLRC4_HD PF17889.1 CEP20200.1 - 0.041 14.2 1.9 0.056 13.8 1.3 1.6 1 1 0 1 1 1 0 NLRC4 helical domain Syntaxin PF00804.25 CEP20200.1 - 0.045 13.4 7.4 0.043 13.5 6.6 1.4 1 1 0 1 1 1 0 Syntaxin DivIC PF04977.15 CEP20200.1 - 0.052 13.3 11.1 0.33 10.8 2.7 2.5 1 1 1 2 2 2 0 Septum formation initiator FlgN PF05130.12 CEP20200.1 - 0.054 14.0 7.1 0.056 14.0 5.8 1.7 2 0 0 2 2 1 0 FlgN protein DUF2205 PF10224.9 CEP20200.1 - 0.058 13.4 1.1 0.058 13.4 1.1 2.1 2 0 0 2 2 2 0 Short coiled-coil protein SOGA PF11365.8 CEP20200.1 - 0.09 13.9 6.8 0.3 12.2 6.8 1.9 1 0 0 1 1 1 0 Protein SOGA FapA PF03961.13 CEP20200.1 - 0.1 11.2 8.6 0.14 10.7 8.6 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CEP20200.1 - 0.12 11.6 3.9 0.22 10.8 3.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF3349 PF11829.8 CEP20200.1 - 0.12 13.1 0.6 0.3 11.9 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) DUF3106 PF11304.8 CEP20200.1 - 0.13 12.7 3.7 0.26 11.8 0.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) V_ATPase_I PF01496.19 CEP20200.1 - 0.14 10.1 4.7 0.14 10.0 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Halogen_Hydrol PF10112.9 CEP20200.1 - 0.14 12.2 2.3 0.24 11.4 1.0 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF5314 PF17241.2 CEP20200.1 - 0.14 11.8 4.2 0.26 10.9 3.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5314) bZIP_1 PF00170.21 CEP20200.1 - 0.17 12.0 11.0 0.19 11.8 3.3 2.8 1 1 1 2 2 2 0 bZIP transcription factor TipAS PF07739.13 CEP20200.1 - 0.22 12.1 2.7 12 6.5 0.2 2.4 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF4407 PF14362.6 CEP20200.1 - 0.24 10.7 3.4 0.27 10.5 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 CEP20200.1 - 0.36 11.0 10.0 2.8 8.1 1.2 3.0 2 0 0 2 2 2 0 Basic region leucine zipper YABBY PF04690.13 CEP20200.1 - 0.36 11.4 2.8 0.54 10.8 2.3 1.6 1 1 0 1 1 1 0 YABBY protein PCRF PF03462.18 CEP20200.1 - 0.45 10.3 8.0 0.59 10.0 7.4 1.5 1 1 0 1 1 1 0 PCRF domain DUF2252 PF10009.9 CEP20200.1 - 0.46 9.5 2.9 0.61 9.1 2.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) RPW8 PF05659.11 CEP20200.1 - 0.47 10.1 6.1 5.5 6.7 0.5 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BMFP PF04380.13 CEP20200.1 - 0.61 10.6 7.5 24 5.5 3.4 3.2 3 0 0 3 3 3 0 Membrane fusogenic activity FlaC_arch PF05377.11 CEP20200.1 - 0.79 10.2 7.0 2 8.9 2.7 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 CEP20200.1 - 0.99 9.7 3.6 12 6.3 3.6 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2433 PF10360.9 CEP20200.1 - 0.99 9.5 4.8 3.2 7.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) TSC22 PF01166.18 CEP20200.1 - 1 9.7 8.5 0.58 10.5 3.7 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Atg14 PF10186.9 CEP20200.1 - 1.1 8.3 9.2 1.9 7.5 8.9 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 CEP20200.1 - 1.1 9.8 20.4 5.7 7.5 19.0 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 CEP20200.1 - 1.1 9.9 4.9 4.4 8.0 1.1 2.5 1 1 1 2 2 2 0 SlyX HALZ PF02183.18 CEP20200.1 - 2.2 8.6 12.8 0.81 10.0 4.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Prominin PF05478.11 CEP20200.1 - 3 5.7 7.0 3.9 5.3 7.0 1.1 1 0 0 1 1 1 0 Prominin DUF2203 PF09969.9 CEP20200.1 - 4.4 8.1 6.8 6.3 7.5 5.6 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Nnf1 PF03980.14 CEP20200.1 - 4.5 7.7 13.8 2.2e+03 -1.0 13.8 2.8 1 1 0 1 1 1 0 Nnf1 Mto2_bdg PF12808.7 CEP20200.1 - 5.2 7.4 9.4 12 6.3 3.3 2.8 2 1 1 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CENP-H PF05837.12 CEP20200.1 - 5.2 7.5 11.1 11 6.4 10.7 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ofd1_CTDD PF10637.9 CEP20202.1 - 6.3e-75 251.8 0.0 3e-69 233.2 0.0 2.6 3 0 0 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CEP20202.1 - 9.5e-32 109.5 0.0 2.6e-31 108.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CEP20202.1 - 6.6e-17 62.2 0.0 2.2e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RVT_1 PF00078.27 CEP20204.1 - 3.1e-27 95.5 0.0 6.9e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CEP20204.1 - 2.7e-05 23.8 0.0 7.8e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CEP20204.1 - 4.5e-05 23.3 0.1 9.5e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_3 PF13358.6 CEP20206.1 - 8.6e-25 87.2 0.1 3e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease PilA4 PF18682.1 CEP20207.1 - 0.098 13.0 0.0 0.46 10.9 0.0 1.8 2 0 0 2 2 2 0 Pilin A4 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Parasitella_parasitica-PP.v1/GCA_000938895.1_PP.v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Parasitella_parasitica-PP.v1/GCA_000938895.1_PP.v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Parasitella_parasitica-PP.v1/GCA_000938895.1_PP.v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Parasitella_parasitica-PP.v1/GCA_000938895.1_PP.v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 03:15:32 2019 # [ok]